Chemoinformatics Profiling of the Chromone Nucleus as a MAO-B/A2AAR Dual Binding Scaffold.

Science.gov (United States)

Cruz-Monteagudo, Maykel; Borges, Fernanda; Cordeiro, M Natalia D S; Helguera, Aliuska Morales; Tejera, Eduardo; Paz-Y-Mino, Cesar; Sanchez-Rodriguez, Aminael; Perera-Sardina, Yunier; Perez-Castillo, Yunierkis

2017-11-14

In the context of the current drug discovery efforts to find disease modifying therapies for Parkinson's disease (PD) the current single target strategy has proved inefficient. Consequently, the search for multi-potent agents is attracting more and more attention due to the multiple pathogenetic factors implicated in PD. Multiple evidences points to the dual inhibition of the monoamine oxidase B (MAO-B), as well as adenosine A2A receptor (A2AAR) blockade, as a promising approach to prevent the neurodegeneration involved in PD. Currently, only two chemical scaffolds has been proposed as potential dual MAO-B inhibitors/A2AAR antagonists (caffeine derivatives and benzothiazinones). In this study, we conduct a series of chemoinformatics analysis in order to evaluate and advance the potential of the chromone nucleus as a MAO-B/A2AAR dual binding scaffold. The information provided by SAR data mining analysis based on network similarity graphs and molecular docking studies support the suitability of the chromone nucleus as a potential MAOB/ A2AAR dual binding scaffold. Additionally, a virtual screening tool based on a group fusion similarity search approach was developed for the prioritization of potential MAO-B/A2AAR dual binder candidates. Among several data fusion schemes evaluated, the MEAN-SIM and MIN-RANK GFSS approaches demonstrated to be efficient virtual screening tools. Then, a combinatorial library potentially enriched with MAO-B/A2AAR dual binding chromone derivatives was assembled and sorted by using the MIN-RANK and then the MEAN-SIM GFSS VS approaches. The information and tools provided in this work represent valuable decision making elements in the search of novel chromone derivatives with a favorable dual binding profile as MAOB inhibitors and A2AAR antagonists with the potential to act as a disease-modifying therapeutic for Parkinson's disease. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Analysis of PROTEUS phase II experiments performed using the AARE modular system and JEF-based libraries

International Nuclear Information System (INIS)

Pelloni, S.; Stepanek, J.; Vontobel, P.

1989-01-01

The capability of the advanced analysis of reactor engineering (AARE) modular code system and JEF-1-based nuclear data libraries to analyze light water high converter reactor (LWHCR) lattices is investigated by calculating the wet and dry cells of the PROTEUS-LWHCR phase II experiment. The results are compared to those obtained using several cell codes. Main features of the AARE code system, such as the self-shielding of resonance cross sections in the whole energy range, the generation of adequate fission source spectra, and the efficiency of the elastic removal correction,are investigated. In particular, it is shown that AARE results for the k ∞ void coefficient agree very well with the experiment, whereas other codes give larger deviations

Teletorn muutub magnetiks / Oliver Õunmaa ; kommenteerinud Aare Siimon, Raili Paling

Index Scriptorium Estoniae

Õunmaa, Oliver

2010-01-01

Aprillis algab aasta aega kestev Tallinna teletorni remont, mille käigus tehtavate muudatuste kohta jagavad selgitusi torni haldava ettevõtte Levira finantsdirektor Aare Siimon ja Arhitektuuribüroo Koko arhitekt Raili Paling

Aare Tool. Piiratud transponeeritavusega heliread ja vorm Eduard Oja muusikas / Mart Jaanson

Index Scriptorium Estoniae

Jaanson, Mart, 1966-

2017-01-01

Arvustus: Aare Tool. Piiratud transponeeritavusega heliread ja vorm Eduard Oja muusikas. Doktoritöö, Eesti Muusika- ja Teatriakadeemia Väitekirjad 7, Tallinn: Eesti Muusika- ja Teatriakadeemia, 2016, 125 lk.

Genome analysis of Excretory/Secretory proteins in Taenia solium reveals their Abundance of Antigenic Regions (AAR).

Science.gov (United States)

Gomez, Sandra; Adalid-Peralta, Laura; Palafox-Fonseca, Hector; Cantu-Robles, Vito Adrian; Soberón, Xavier; Sciutto, Edda; Fragoso, Gladis; Bobes, Raúl J; Laclette, Juan P; Yauner, Luis del Pozo; Ochoa-Leyva, Adrián

2015-05-19

Excretory/Secretory (ES) proteins play an important role in the host-parasite interactions. Experimental identification of ES proteins is time-consuming and expensive. Alternative bioinformatics approaches are cost-effective and can be used to prioritize the experimental analysis of therapeutic targets for parasitic diseases. Here we predicted and functionally annotated the ES proteins in T. solium genome using an integration of bioinformatics tools. Additionally, we developed a novel measurement to evaluate the potential antigenicity of T. solium secretome using sequence length and number of antigenic regions of ES proteins. This measurement was formalized as the Abundance of Antigenic Regions (AAR) value. AAR value for secretome showed a similar value to that obtained for a set of experimentally determined antigenic proteins and was different to the calculated value for the non-ES proteins of T. solium genome. Furthermore, we calculated the AAR values for known helminth secretomes and they were similar to that obtained for T. solium. The results reveal the utility of AAR value as a novel genomic measurement to evaluate the potential antigenicity of secretomes. This comprehensive analysis of T. solium secretome provides functional information for future experimental studies, including the identification of novel ES proteins of therapeutic, diagnosis and immunological interest.

Aare Sosaar nõuab sisse ERA Panga halbu laene / Tiit Elner

Index Scriptorium Estoniae

Elner, Tiit

2000-01-01

Ekspankur Aare Sosaare juhitav teadmata omanikega ERA Liising ostis pankrotis ERA Pangalt probleemseid laene, suurem nõuete ostja oli ka Krediidipank. Kokku on müüdud laenude lepingujärgne väärtus kuni 100 mln. kr.

Estonia : a European tax paradise? / Aare Kurist, Madis Müller

Index Scriptorium Estoniae

Kurist, Aare, 1974-

2003-01-01

PricewaterhouseCoopersi maksuosakonna juhataja Aare Kurist ja peaministri majandusnõunik Madis Müller analüüsivad 2000. aastal toimunud maksureformi eesmärke ja nende täitmist, prognoosivad EL-i liitumisläbirääkimiste võimalikku mõju Eesti maksupoliitikale ja võimalikku vajadust tulevikus Eesti maksukorralduse muutmiseks

A subaquatic moraine complex in overdeepened Lake Thun (Switzerland) unravelling the deglaciation history of the Aare Glacier

Science.gov (United States)

Fabbri, S. C.; Buechi, M. W.; Horstmeyer, H.; Hilbe, M.; Hübscher, C.; Schmelzbach, C.; Weiss, B.; Anselmetti, F. S.

2018-05-01

To investigate the history of the Aare Glacier and its overdeepened valley, a high-resolution multibeam bathymetric dataset and a 2D multi-channel reflection seismic dataset were acquired on perialpine Lake Thun (Switzerland). The overdeepened basin was formed by a combination of tectonically predefined weak zones and glacial erosion during several glacial cycles. In the deepest region of the basin, top of bedrock lies at ∼200 m below sea level, implying more than 750 m of overdeepening with respect to the current fluvial base level (i.e. lake level). Seismic stratigraphic analysis reveals the evolution of the basin and indicates a subaquatic moraine complex marked by high-amplitude reflections below the outermost edge of a morphologically distinct platform in the southeastern part of the lake. This stack of seven subaquatic terminal moraine crests was created by a fluctuating, "quasi-stagnant" grounded Aare Glacier during its overall recessional phase. Single packages of overridden moraine crests are seismically distuinguishable, which show a transition downstream into prograding clinoforms with foresets at the ice-distal slope. The succession of subaquatic glacial sequences (foresets and adjacent bottomsets) represent one fifth of the entire sedimentary thickness. Exact time constraints concerning the deglacial history of the Aare Glacier are very sparse. However, existing 10Be exposure ages from the accumulation area of the Aare Glacier and radiocarbon ages from a Late-Glacial lake close to the outlet of Lake Thun indicate that the formation of the subaquatic moraine complex and the associated sedimentary infill must have occurred in less than 1000 years, implying high sedimentation rates and rapid disintegration of the glacier. These new data improve our comprehension of the landforms associated with the ice-contact zone in water, the facies architecture of the sub- to proglacial units, the related depositional processes, and thus the retreat mechanisms of

AAR at Hydro-Quebec : a review of field cases and intervention strategies

Energy Technology Data Exchange (ETDEWEB)

Durand, B. [Hydro-Quebec, Varennes, PQ (Canada). IREQ

2006-07-01

Hydro-Quebec owns and operates more than 560 dams, including 200 dams that are classified as large dams. By 2010, approximately 150 of the concrete dams will be at least 50 years old, and nearly 100 of the dams will be 70 years old. The current condition of these structures reflects the influence of several factors that have promoted aging, such as initial shrinkage causing latent microcracking; expansion and contraction related to temperature cycles; larger infiltration entailing increased uplift; leaching and deposition of calcium salts that clog joints and drains; hydric swelling; freezing and thawing cycles; erosion; sulfation; and, alkali-aggregate reactions (AAR). This paper focused on the swelling due to AAR, since more than 20 dams have been affected by this condition. Hydro-Quebec's approach to prevent AAR was described. In response to Canadian Standards Association (CSA) concrete expansion tests, Hydro-Quebec no longer allows admixtures for its concrete structures. Rather, non-reactive aggregates are used in the concrete. This paper also discussed the evaluation of residual expansion time caused by the alkali-silica reaction (ASR), which has affected the dam at La Tuque in the Mauricie Region. Results of laboratory expansion tests have been compared with the average expansion rate measured at the La Tuque dam. It was estimated that the concrete should continue to swell for at least 20 years at the same rate as measured since 1979. After that, expansion may possibly slow down due to self-confinement in the concrete. However, if confinement increases in 2 directions, it is probable that the expansion accelerates in the third direction. 26 refs., 3 tabs., 8 figs.

Research on Standard and Automatic Judgment of Press-fit Curve of Locomotive Wheel-set Based on AAR Standard

Science.gov (United States)

Lu, Jun; Xiao, Jun; Gao, Dong Jun; Zong, Shu Yu; Li, Zhu

2018-03-01

In the production of the Association of American Railroads (AAR) locomotive wheel-set, the press-fit curve is the most important basis for the reliability of wheel-set assembly. In the past, Most of production enterprises mainly use artificial detection methods to determine the quality of assembly. There are cases of miscarriage of justice appear. For this reason, the research on the standard is carried out. And the automatic judgment of press-fit curve is analysed and designed, so as to provide guidance for the locomotive wheel-set production based on AAR standard.

The small hydropower plant in the old river Aare in Niedergoesgen, Switzerland; Kleinwasserkraftwerk Ballyschwelle, alte Aare, Niedergoesgen. Vorprojekt

Energy Technology Data Exchange (ETDEWEB)

Eichenberger, P.

2007-07-15

This preliminary project for the Swiss Federal Office of Energy (SFOE) presents a project which proposes the construction of a new small hydro plant in Niedergoesgen/Gretzenbach, Switzerland, that is to make use of the waters of the old river Aare. The project proposes the construction of a new, 350 kW plant at the site of an existing sill across the old river that originally formed part of a water-power installation given up in 1917. The existing parts of the old installation are described and the legal situation concerning water rights and land ownership are examined. Three variants for a new installation are described. Technical figures and energy-production estimates for a new installation are discussed. Ecological aspects are examined, as are the recreational aspects of the river at this location. Cost estimates and economic viability are discussed.

Piimatööstused kukkusid kahjumisse / Aare Annus ; interv. Silja Lättemäe

Index Scriptorium Estoniae

Annus, Aare

2005-01-01

Tallinna Piimatööstuse AS-i nõukogu esimees Aare Annus Eesti piimatööstuste raskest olukorrast seoses toorpiima kõrge kokkuostuhinnaga. Vt. ka: Kas saite piimahinnast kõva kasumit? Küsimusele vastavad Järvamaa talunik Arvo Kuutok ja Põlva Agro OÜ nõukogu esimees Jaak Hinrikus

Adult Attachment Ratings (AAR): an item response theory analysis.

Science.gov (United States)

Pilkonis, Paul A; Kim, Yookyung; Yu, Lan; Morse, Jennifer Q

2014-01-01

The Adult Attachment Ratings (AAR) include 3 scales for anxious, ambivalent attachment (excessive dependency, interpersonal ambivalence, and compulsive care-giving), 3 for avoidant attachment (rigid self-control, defensive separation, and emotional detachment), and 1 for secure attachment. The scales include items (ranging from 6-16 in their original form) scored by raters using a 3-point format (0 = absent, 1 = present, and 2 = strongly present) and summed to produce a total score. Item response theory (IRT) analyses were conducted with data from 414 participants recruited from psychiatric outpatient, medical, and community settings to identify the most informative items from each scale. The IRT results allowed us to shorten the scales to 5-item versions that are more precise and easier to rate because of their brevity. In general, the effective range of measurement for the scales was 0 to +2 SDs for each of the attachment constructs; that is, from average to high levels of attachment problems. Evidence for convergent and discriminant validity of the scales was investigated by comparing them with the Experiences of Close Relationships-Revised (ECR-R) scale and the Kobak Attachment Q-sort. The best consensus among self-reports on the ECR-R, informant ratings on the ECR-R, and expert judgments on the Q-sort and the AAR emerged for anxious, ambivalent attachment. Given the good psychometric characteristics of the scale for secure attachment, however, this measure alone might provide a simple alternative to more elaborate procedures for some measurement purposes. Conversion tables are provided for the 7 scales to facilitate transformation from raw scores to IRT-calibrated (theta) scores.

The timing of the maximum extent of the Rhone Glacier at Wangen a.d. Aare

Energy Technology Data Exchange (ETDEWEB)

Ivy-Ochs, S.; Schluechter, C. [Bern Univ. (Switzerland); Kubik, P.W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Beer, J. [EAWAG, Duebendorf (Switzerland)

1997-09-01

Erratic blocks found in the region of Wangen a.d. Aare delineate the maximum position of the Solothurn lobe of the Rhone Glacier. {sup 10}Be and {sup 26}Al exposure ages of three of these blocks show that the glacier withdraw from its maximum position at or slightly before 20,000{+-}1800 years ago. (author) 1 fig., 5 refs.

Genotype/phenotype correlations in AARS-related neuropathy in a cohort of patients from the United Kingdom and Ireland.

Science.gov (United States)

Bansagi, Boglarka; Antoniadi, Thalia; Burton-Jones, Sarah; Murphy, Sinead M; McHugh, John; Alexander, Michael; Wells, Richard; Davies, Joanna; Hilton-Jones, David; Lochmüller, Hanns; Chinnery, Patrick; Horvath, Rita

2015-08-01

Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy with heterogeneous clinical presentation and genetic background. The axonal form (CMT2) is characterised by decreased action potentials indicating primary axonal damage. The underlying pathology involves axonal degeneration which is supposed to be related to axonal protein dysfunction caused by various gene mutations. The overlapping clinical manifestation of CMT2 with distal hereditary motor neuropathy (dHMN) and intermediate CMT causes further diagnostic difficulties. Aminoacyl-tRNA synthetases have been implicated in the pathomechanism of CMT2. They have an essential role in protein translation by attaching amino acids to their cognate tRNAs. To date six families have been reported worldwide with dominant missense alanyl-tRNA synthetase (AARS) mutations leading to clinically heterogeneous axonal neuropathies. The pathomechanism of some variants could be explained by impaired amino acylation activity while other variants implicating an editing defect need to be further investigated. Here, we report a cohort of six additional families originating from the United Kingdom and Ireland with dominant AARS-related neuropathies. The phenotypic manifestation was distal lower limb predominant sensorimotor neuropathy but upper limb impairment with split hand deformity occasionally associated. Nerve conduction studies revealed significant demyelination accompanying the axonal lesion in motor and sensory nerves. Five families have the c.986G>A, p.(Arg329His) variant, further supporting that this is a recurrent loss of function variant. The sixth family, of Irish origin, had a novel missense variant, c.2063A>G, p.(Glu688Gly). We discuss our findings and the associated phenotypic heterogeneity in these families, which expands the clinical spectrum of AARS-related neuropathies.

Avaliku võimu ja kodanikualgatuse partnerlus : koostööd mõjutavad tegurid / Krista Hinno, Tanel Vallimäe

Index Scriptorium Estoniae

Hinno, Krista

2007-01-01

Artiklis esitatakse kokkuvõte Tallinna Ülikooli Eesti Humanitaarinstituudi Kodanikeühiskonna Uurimis- ja Arenduskeskuse uurimuse "Avaliku võimu ja kodanikualgatuse komplementaarsed suhted" peamistest tulemustest. Raporti autorite hulka kuulusid Erle Rikmann, Krista Hinno, Aigi Bremse, Kersti Kollom, Mari Sepp ja Tanel Vallimäe. Toetudes uuringutele väidavad autorid, et Eesti ametnikkond on soodsalt meelestatud koostööle kodanikuühendustega, takistuseks võivad saada kodanikeühenduste erinev tööstiil, vajalike ressursside puudus, sh ka ajanappus, ametnike kaadrivoolavus ja teatavate vanusegruppide vähene avatus. Diagrammid: Koostöö jaotumine asutuseliikide vahel; Ametnike hinnang ühistegevuse sisukusele seoses koostöö algatamisega; Ametnike hinnang omaduse vajalikkusele oma töös (vastajate osakaal, kes peavad antud omadust oma töös väga vajalikuks)

Quantification and dating of floodplain sedimentation in a medium-sized catchment of the German uplands: a case study from the Aar Valley in the southern Rhenish Massif, Germany

Directory of Open Access Journals (Sweden)

Stolz, Christian

2013-09-01

Full Text Available The distribution, thickness and composition of the floodplain sediments in the valleys of the Aar and its tributaries (Taunus Mountains were investigated by way of extensive fieldwork at 25 locations. In the entire catchment area, 48.8 million tons of loamy f loodplain fines could be assessed. Most of these were deposited since late medieval times due to extensive historical land use and forest clearing, especially in the mining region along the middle course of the Aar. In its lower course, the enhanced sedimentation of loamy f loodplain sediments started during the Bronze Age.

Internal structure of the Aar Massif: What can we learn in terms of exploration for deep geothermal energy?

Science.gov (United States)

Herwegh, Marco; Baumberger, Roland; Wehrens, Philip; Schubert, Raphael; Berger, Alfons; Maeder, Urs; Spillmann, Thomas

2014-05-01

The successful use of deep geothermal energy requires 3D flow paths, which allow an efficient heat exchange between the surrounding host rocks and the circulating fluids. Recent attempts to exploit this energy resource clearly demonstrate that the new technology is facing sever problems. Some major problems are related to the prediction of permeability, the 3D structure of the flow paths and the mechanical responses during elevated fluid pressures at depths of several kilometers. Although seemingly new in a technical perspective, nature is facing and solving similar problems since the beginning of the Alpine orogeny. Based on detailed studies in the Hasli Valley (Aar Massif) we can demonstrate that deformation and fluid flow are strongly localized along mechanical anisotropies (e.g. lithological variations, brittle and ductile faults). Some of them already evolved during Variscan and post-Variscan times. Interestingly, these inherited structures are reactivated over and over again during the Alpine orogeny. Their reactivation occurred at depths of ~13-15 km with elevated temperatures (400-475°C) and involved both ductile and brittle deformation processes. Brittle deformation in form of hydrofracking was always present due to the circulating fluids. It is this process, which was and still is responsible for seismic activity. With progressive uplift and exhumation of the Aar Massif, ductile deformation structures became replaced by brittle cataclasites and fault gouges during fault activity at shallower crustal levels. Existing hydrotest data from the Grimsel Test Site (Nagra's underground research laboratory) indicate that these brittle successors of the ductile shear zones are domains of enhanced recent fluid percolation. Note that although being exposed today, the continuation of these fault structures are still active at depth in both brittle and ductile deformation modes, a fact that can be inferred from recent uplift rates and the active seismicity. On the

Automation of hydro power on the upper Rhine and modernization of a power station at the confluence of the Rhine and Aare rivers; Automatisierung der Wasserwirtschaft am Hochrhein und Modernisierung eines Kraftwerkes am Zusammenfluss von Aare und Rhein

Energy Technology Data Exchange (ETDEWEB)

Beltzig, C.; Schlageter, G.

1996-12-31

For the first barrage weir after the confluence of the Rhine and Aare rivers, a maximum storage level is determined and set that constitutes an operating optimum and takes the different inflow and outfall volumes as well as existing retention capacities into account. Moreover, the process control system ensures automatic operation of the three engine units of the power station including process control of the barrage weir and the external systems belonging to the Albbruck-Doggern hydroelectric power station on the Rhine (RADAG). (orig./RHM)

The small hydropower plant in the old river Aare in Niedergoesgen, Switzerland

International Nuclear Information System (INIS)

Eichenberger, P.

2007-07-01

This preliminary project for the Swiss Federal Office of Energy (SFOE) presents a project which proposes the construction of a new small hydro plant in Niedergoesgen/Gretzenbach, Switzerland, that is to make use of the waters of the old river Aare. The project proposes the construction of a new, 350 kW plant at the site of an existing sill across the old river that originally formed part of a water-power installation given up in 1917. The existing parts of the old installation are described and the legal situation concerning water rights and land ownership are examined. Three variants for a new installation are described. Technical figures and energy-production estimates for a new installation are discussed. Ecological aspects are examined, as are the recreational aspects of the river at this location. Cost estimates and economic viability are discussed.

Using the accelerated Brazilian concrete prism test (ABCPT to evaluate alkali aggregate reaction (AAR

Directory of Open Access Journals (Sweden)

L. Sanchez

Full Text Available There are many test methods used in the laboratory to detect potential alkali-aggregate reactions (AAR. However, up to now, there is no consensus if they are reliable and efficient. This work presents the development of a new and accelerated concrete prism test called ABCPT (accelerate Brazilian concrete prism test as an attempt to create a reliable and fast test that can analyze and classify the potential reactivity of aggregates in the laboratory. For this research, six aggregates from different lithotypes were used. The methods CPT, ACPT and ABCPT were carried out with all the aggregates and a comparative analysis among all tests was performed. ABCPT seems to have a great potential to analyze and classify aggregates in the laboratory, although it needs further testing with other lithotypes to be confirmed as feasible.

Structural modeling of tissue-specific mitochondrial alanyl-tRNA synthetase (AARS2 defects predicts differential effects on aminoacylation

Directory of Open Access Journals (Sweden)

Liliya eEuro

2015-02-01

Full Text Available The accuracy of mitochondrial protein synthesis is dependent on the coordinated action of nuclear-encoded mitochondrial aminoacyl-tRNA synthetases (mtARSs and the mitochondrial DNA-encoded tRNAs. The recent advances in whole-exome sequencing have revealed the importance of the mtARS proteins for mitochondrial pathophysiology since nearly every nuclear gene for mtARS (out of 19 is now recognized as a disease gene for mitochondrial disease. Typically, defects in each mtARS have been identified in one tissue-specific disease, most commonly affecting the brain, or in one syndrome. However, mutations in the AARS2 gene for mitochondrial alanyl-tRNA synthetase (mtAlaRS have been reported both in patients with infantile-onset cardiomyopathy and in patients with childhood to adulthood-onset leukoencephalopathy. We present here an investigation of the effects of the described mutations on the structure of the synthetase, in an effort to understand the tissue-specific outcomes of the different mutations.The mtAlaRS differs from the other mtARSs because in addition to the aminoacylation domain, it has a conserved editing domain for deacylating tRNAs that have been mischarged with incorrect amino acids. We show that the cardiomyopathy phenotype results from a single allele, causing an amino acid change p.R592W in the editing domain of AARS2, whereas the leukodystrophy mutations are located in other domains of the synthetase. Nevertheless, our structural analysis predicts that all mutations reduce the aminoacylation activity of the synthetase, because all mtAlaRS domains contribute to tRNA binding for aminoacylation. According to our model, the cardiomyopathy mutations severely compromise aminoacylation whereas partial activity is retained by the mutation combinations found in the leukodystrophy patients. These predictions provide a hypothesis for the molecular basis of the distinct tissue-specific phenotypic outcomes.

"Loomakari" kui uue ühiskonnakorralduse näide / Ernest Truely ; tõlkinud Ulla Juske

Index Scriptorium Estoniae

Truely, Ernest

2009-01-01

Sandra Jõgeva kuraatoriprojektist "Loomakari" Tallinna Kunstihoones, avatud 12. aprillini. Kujundaja Tanel Saar. Sandra Jõgeva, Tanel Saare, Anthony Faroux' (Inglismaa), Jenni Juulia Wallinheimo (Soome) ja Kjetil Kauslandi (Norra) töödest

Sügisene moevaatemäng / Britt Rosen

Index Scriptorium Estoniae

Rosen, Britt, 1968-

2008-01-01

FIBITi moepäevad Viru keskuses, korraldaja Anu Kikas. Arne Niidu, Anu Samarüütel-Longi, Tanel Veenre kollektsioonidest. Kalle Aasamäe, Lilli Jahilo, Aet Alevi, Anu Samarüütel-Longi ja Tanel Veenre kommentaarid

Laanmäes leidub ainest Värniku mantlipärijaks / Deivil Tserp

Index Scriptorium Estoniae

Tserp, Deivil, 1968-

2007-01-01

Tanel Laanmäe ei jäänud oma esinemisega alla 20-aastaste EMil Hengelos rahule, kuid kodustel jõuproovidel virutab tulevikulootus oda kaugele. Vt. samas: Treener Toomas Merilat rõõmustab Tanel Laanmäe töökus

Diagnostic Accuracy of APRI, AAR, FIB-4, FI, and King Scores for Diagnosis of Esophageal Varices in Liver Cirrhosis: A Retrospective Study.

Science.gov (United States)

Deng, Han; Qi, Xingshun; Peng, Ying; Li, Jing; Li, Hongyu; Zhang, Yongguo; Liu, Xu; Sun, Xiaolin; Guo, Xiaozhong

2015-12-20

BACKGROUND Aspartate aminotransferase-to-platelet ratio index (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), FIB-4, fibrosis index (FI), and King scores might be alternatives to the use of upper gastrointestinal endoscopy for the diagnosis of esophageal varices (EVs) in liver cirrhosis. This study aimed to evaluate their diagnostic accuracy in predicting the presence and severity of EVs in liver cirrhosis. MATERIAL AND METHODS All patients who were consecutively admitted to our hospital and underwent upper gastrointestinal endoscopy between January 2012 and June 2014 were eligible for this retrospective study. Areas under curve (AUCs) were calculated. Subgroup analyses were performed according to the history of upper gastrointestinal bleeding (UGIB) and splenectomy. RESULTS A total of 650 patients with liver cirrhosis were included, and 81.4% of them had moderate-severe EVs. In the overall analysis, the AUCs of these non-invasive scores for predicting moderate-severe EVs and presence of any EVs were 0.506-0.6 and 0.539-0.612, respectively. In the subgroup analysis of patients without UGIB, their AUCs for predicting moderate-severe varices and presence of any EVs were 0.601-0.664 and 0.596-0.662, respectively. In the subgroup analysis of patients without UGIB or splenectomy, their AUCs for predicting moderate-severe varices and presence of any EVs were 0.627-0.69 and 0.607-0.692, respectively. CONCLUSIONS APRI, AAR, FIB-4, FI, and King scores had modest diagnostic accuracy of EVs in liver cirrhosis. They might not be able to replace the utility of upper gastrointestinal endoscopy for the diagnosis of EVs in liver cirrhosis.

Doktoritöödes näeb eestiainelisust / Lembitu Reio

Index Scriptorium Estoniae

Reio, Lembitu, 1924-

2004-01-01

Uppsala Ülikoolis ja Karolinska Instituudis kaitsesid oma doktoritöid: Ann Grubbström, Sigrid Hedin, Salme Timmusk, Anton Terasmaa, Tanel Punga, Mari Kadi. Tanel Käämbrele määras Rootsi Kuninglik Teadusselts 2003. aasta füüsikaauhinna

Õhuloss ehk tuletorni juurde / Tiina Käesel ; kommenteerinud Tamara Luuk

Index Scriptorium Estoniae

Käesel, Tiina, 1943-

2011-01-01

Ehtekunstinäitus "Õhuloss" Tallinna Põhjatuletornis 25. septembrini 2011. Näitusega kaasneb raamat "Castle in the Air - Jewellery from Estonia - Õhuloss", koostajad Kadri Mälk ja Tanel Veenre. Rühmitusse "õhuLoss" kuuluvad Kadri Mälk, Piret Hirv, Eve Margus-Villems, Kristiina Laurits, Villu Plink, Tanel Veenre, Katrin Sipelgas

Tolko poetom hotel bõt : Rastrogannost; Dozhdlivõi den; Jaanov ogon; Setumaa I-II; Tolko poetom. Haralskije zhizneopissanija : Aire Valgus; Aare Valgus; Peeter Petrov; Vaike Metsleht; Valdur Laiapea; Hillar Aruda, ekonomist; Pärja Lumendi; Valjo Z

Index Scriptorium Estoniae

Traat, Mats, 1936-

1996-01-01

Orig.: Heldimus; Sajupäev; Jaanituli; Setumaa I-II; Ainult poeet. Harala elulood: Aire Valgus; Aare Valgus; Peeter Petrov; Vaike Metsleht; Valdur Laiapea; Hillar Aruda, ökonomist; Pärja Lumendi; Valjo Zeiger; Pavlo Moskalenko; Johannes Iva; Viljar Laanemägi; Olga Kaljusaar; Aimi Vaimets; Einard Kalm (1923-1984); Sonetid vaikimisest I; Kui

Nahaga kaetud ihu / Kristi Paap

Index Scriptorium Estoniae

Paap, Kristi

2008-01-01

Rahvusvaheline näitus "2nd skin. Korgipuust ehted" Eesti Tarbekunsti- ja disainimuuseumis kuni 24. IV. Eestist osalevad näitusel Kadri Mälk, Tanel Veenre ja Tõnis Malkov. Carla Castiajo, Eija Mustoneni, Ramon Puig Cuyas'i, Jose Carlos Marquesi, Leonor Hipolito, Tanel Veenre, Gisela Ribeiro ja Kadri Mälgu töödest

SU-E-T-644: QuAArC: A 3D VMAT QA System Based On Radiochromic Film and Monte Carlo Simulation of Log Files

Energy Technology Data Exchange (ETDEWEB)

Barbeiro, A.R.; Ureba, A.; Baeza, J.A.; Jimenez-Ortega, E.; Plaza, A. Leal [Universidad de Sevilla, Departamento de Fisiologia Medica y Biofisica, Seville (Spain); Linares, R. [Hospital Infanta Luisa, Servicio de Radiofisica, Seville (Spain); Mateos, J.C.; Velazquez, S. [Hospital Universitario Virgen del Rocio, Servicio de Radiofisica, Seville (Spain)

2015-06-15

Purpose: VMAT involves two main sources of uncertainty: one related to the dose calculation accuracy, and the other linked to the continuous delivery of a discrete calculation. The purpose of this work is to present QuAArC, an alternative VMAT QA system to control and potentially reduce these uncertainties. Methods: An automated MC simulation of log files, recorded during VMAT treatment plans delivery, was implemented in order to simulate the actual treatment parameters. The linac head models and the phase-space data of each Control Point (CP) were simulated using the EGSnrc/BEAMnrc MC code, and the corresponding dose calculation was carried out by means of BEAMDOSE, a DOSXYZnrc code modification. A cylindrical phantom was specifically designed to host films rolled up at different radial distances from the isocenter, for a 3D and continuous dosimetric verification. It also allows axial and/or coronal films and point measurements with several types of ion chambers at different locations. Specific software was developed in MATLAB in order to process and evaluate the dosimetric measurements, which incorporates the analysis of dose distributions, profiles, dose difference maps, and 2D/3D gamma index. It is also possible to obtain the experimental DVH reconstructed on the patient CT, by an optimization method to find the individual contribution corresponding to each CP on the film, taking into account the total measured dose, and the corresponding CP dose calculated by MC. Results: The QuAArC system showed high reproducibility of measurements, and consistency with the results obtained with the commercial system implemented in the verification of the evaluated treatment plans. Conclusion: A VMAT QA system based on MC simulation and high resolution dosimetry with film has been developed for treatment verification. It shows to be useful for the study of the real VMAT capabilities, and also for linac commissioning and evaluation of other verification devices.

Pärnu on Eesti funktsionalismi lipulaev / Anu Villmann

Index Scriptorium Estoniae

Villmann, Anu

2006-01-01

Pärnu uusehitistest - Seedri tänava elamud (arhitekt Kalle Vellevoog), kortermaja Tammsaare ja Lehe tänava nurgal (arhitekt Tanel Tuhal arhitektuuribüroost Luhse ja Tuhal) ja kesklinna koolide võimla (arhitektid Katrin Koov, Siiri Vallner, Kaire Nõmm ja Heidi Urb arhitektuuribüroost KAVA KAVA). Pärnu arhitektuurist võtavad sõna Pärnu Linnavalitsuse arhitekt Karri Tiigisoon, Helle-Ann Urgard, Tanel Tuhal, Hardi Lehemaa ja Toomas Unt

"Avamaa" ehk Kuidas kasutada ära meie maaelu võimalusi? / Evelyn Müürsepp

Index Scriptorium Estoniae

Müürsepp, Evelyn

2008-01-01

Kunstisümpoosion "Avamaa" Mooste Kunsti- ja Sotsiaalpraktika Keskuses 18.-23. VIII. Tero Nauha, Siim Angerpiku, rühmituse Lahe Atmosfäär, Patrick McGinley ja John Grzinichi kureeritud töötubadest. 23. VIII eksperimentaalse folkmuusika kontserdil "Mesi kõrvadele" esinesid Launau, Lauhkeat Lampaat ja Kuupuu Soomest, Michele Spanghero Itaaliast, Riho Kall, Vaikuse Koosolek (Anna Hints, Helen Kõmmus, Maria Rõhu, Marja-Liisa Plats, Tanel Kaupan), Mari Kalkun ja Tanel Kadalipp Eestist ning Bernu Rits Lätist

Quantitative assessment of alkali-reactive aggregate mineral content through XRD using polished sections as a supplementary tool to RILEM AAR-1 (petrographic method)

International Nuclear Information System (INIS)

Castro, Nélia; Sorensen, Bjørn E.; Broekmans, Maarten A.T.M.

2012-01-01

The mineral content of 5 aggregate samples from 4 different countries, including reactive and non-reactive aggregate types, was assessed quantitatively by X-ray diffraction (XRD) using polished sections. Additionally, electron probe microanalyzer (EPMA) mapping and cathodoluminescence (CL) were used to characterize the opal-CT identified in one of the aggregate samples. Critical review of results from polished sections against traditionally powdered specimen has demonstrated that for fine-grained rocks without preferred orientation the assessment of mineral content by XRD using polished sections may represent an advantage over traditional powder specimens. Comparison of data on mineral content and silica speciation with expansion data from PARTNER project confirmed that the presence of opal-CT plays an important role in the reactivity of one of the studied aggregates. Used as a complementary tool to RILEM AAR-1, the methodology suggested in this paper has the potential to improve the strength of the petrographic method.

The Incidence, Classification, and Management of Acute Adverse Reactions to the Low-Osmolar Iodinated Contrast Media Isovue and Ultravist in Contrast-Enhanced Computed Tomography Scanning.

Science.gov (United States)

Zhang, Bin; Dong, Yuhao; Liang, Long; Lian, Zhouyang; Liu, Jing; Luo, Xiaoning; Chen, Wenbo; Li, Xinyu; Liang, Changhong; Zhang, Shuixing

2016-03-01

Some epidemiologic surveillance studies have recorded adverse drug reactions to radiocontrast agents. We aimed to investigate the incidence and management of acute adverse reactions (AARs) to Ultravist-370 and Isovue-370 in patients who underwent contrast-enhanced computed tomography (CT) scanning.Data from 137,473 patients were analyzed. They had undergone enhanced CT scanning with intravenous injection of Ultravist-370 or Isovue-370 during the period of January 1, 2006 to December 31, 2012 in our hospital. We investigated and classified AARs according to the American College of Radiology and the Chinese Society of Radiology (CSR) guidelines for iodinated contrast media. We analyzed risk factors for AARs and compared the AARs induced by Ultravist-370 and Isovue-370.Four hundred and twenty-eight (0.31%) patients experienced AARs, which included 330 (0.24%) patients with mild AARs, 82 (0.06%) patients with moderate AARs, and 16 (0.01%) patients with severe AARs (including 3 cases of cardiac arrest and one case of death). The incidence of AARs was higher with Ultravist-370 than with Isovue-370 (0.38% vs 0.24%, P management, the symptoms and signs of 96.5% of the AARs resolved within 24 hours without sequelae.Ultravist-370 and Isovue-370 are safe for patients undergoing enhanced CT scanning. The incidence of AARs is higher with Ultravist-370 than with Isovue-370, but this difference is limited only to the mild AARs. The incidence of AARs could be affected by multiple factors.

DVD. Aare Ermel tutvustab / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Eluloofilm "Lermontov" : režissöör Nikolai Burljajev : NSV Liit 1986 ja teleseriaal "Petshorin: meie aja kangelane" ("Petshorin: geroi nashego vremeni") : režissöör Aleksandr Kott : nimiosas Igor Petrenko : Venemaa 2006

GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats.

Directory of Open Access Journals (Sweden)

Lei Ding

Full Text Available Chemical stimulation of white adipose tissue (WAT induces adipose afferent reflex (AAR, and thereby causes a general sympathetic activation. Paraventricular nucleus (PVN is important in control of sympathetic outflow. This study was designed to investigate the role of γ-aminobutyric acid (GABA in PVN in regulating the AAR.Experiments were carried out in anesthetized rats. Renal sympathetic nerve activity (RSNA and mean arterial pressure (MAP were continuously recorded. AAR was evaluated by the RSNA and MAP responses to electrical stimulation of the right epididymal WAT (eWAT afferent nerve. Electrical stimulation of eWAT afferent nerve increase RSNA. Bilateral microinjection of the GABAA receptor agonist isoguvacine or the GABAB receptor agonist baclofen attenuated the AAR. The effect of isoguvacine on the AAR was greater than that of baclofen. The GABAA receptor antagonist gabazine enhanced the AAR, while the GABAB receptor antagonist CGP-35348 had no significant effect on the AAR. Bilateral PVN microinjection of vigabatrin, a selective GABA-transaminase inhibitor, to increase endogenous GABA levels in the PVN abolished the AAR. The inhibitory effect of vigabatrin on the AAR was attenuated by the pretreatment with gabazine or CGP-35348. Pretreatment with combined gabazine and CGP-35348 abolished the effects of vigabatrin.Activation of GABAA or GABAB receptors in the PVN inhibits the AAR. Blockade of GABAA receptors in the PVN enhances the AAR. Endogenous GABA in the PVN plays an important role in regulating the AAR.

The adenosine A2A receptor — Myocardial protectant and coronary target in endotoxemia

Science.gov (United States)

Reichelt, Melissa E.; Ashton, Kevin J.; Tan, Xing Lin; Mustafa, S. Jamal; Ledent, Catherine; Delbridge, Lea M.D.; Hofmann, Polly A.; Headrick, John P.; Morrison, R. Ray

2013-01-01

Background Cardiac injury and dysfunction are contributors to disease progression and mortality in sepsis. This study evaluated the cardiovascular role of intrinsic A2A adenosine receptor (A2AAR) activity during lipopolysaccharide (LPS)-induced inflammation. Methods We assessed the impact of 24 h of LPS challenge (20 mg/kg, IP) on cardiac injury, coronary function and inflammatory mediator levels in Wild-Type (WT) mice and mice lacking functional A2AARs (A2AAR KO). Results Cardiac injury was evident in LPS-treated WTs, with ∼7-fold elevation in serum cardiac troponin I (cTnI), and significant ventricular and coronary dysfunction. Absence of A2AARs increased LPS-provoked cTnI release at 24 h by 3-fold without additional demise of contraction function. Importantly, A2AAR deletion per se emulated detrimental effects of LPS on coronary function, and LPS was without effect in coronary vessels lacking A2AARs. Effects of A2AAR KO were independent of major shifts in circulating C-reactive protein (CRP) and haptoglobin. Cytokine responses were largely insensitive to A2AAR deletion; substantial LPS-induced elevations (up to 100-fold) in IFN-γ and IL-10 were unaltered in A2AAR KO mice, as were levels of IL-4 and TNF-α. However, late elevations in IL-2 and IL-5 were differentially modulated by A2AAR KO (IL-2 reduced, IL-5 increased). Data demonstrate that in the context of LPS-triggered cardiac and coronary injury, A2AAR activity protects myocardial viability without modifying contractile dysfunction, and selectively modulates cytokine (IL-2, IL-5) release. A2AARs also appear to be targeted by LPS in the coronary vasculature. Conclusions These experimental data suggest that preservation of A2AAR functionality might provide therapeutic benefit in human sepsis. PMID:22192288

Aspartic acid racemisation in purified elastin from arteries as basis for age estimation.

Science.gov (United States)

Dobberstein, R C; Tung, S-M; Ritz-Timme, S

2010-07-01

Aspartic acid racemisation (AAR) results in an age-dependent accumulation of D: -aspartic acid in durable human proteins and can be used as a basis for age estimation. Routinely, age estimation based on AAR is performed by analysis of dentine. However, in forensic practise, teeth are not always available. Non-dental tissues for age estimation may be suitable for age estimation based on AAR if they contain durable proteins that can be purified and analysed. Elastin is such a durable protein. To clarify if purified elastin from arteries is a suitable sample for biochemical age estimation, AAR was determined in purified elastin from arteries from individuals of known age (n = 68 individuals, including n = 15 putrefied corpses), considering the influence of different stages of atherosclerosis and putrefaction on the AAR values. AAR was found to increase with age. The relationship between AAR and age was good enough to serve as basis for age estimation, but worse than known from dentinal proteins. Intravital and post-mortem degradation of elastin may have a moderate effect on the AAR values. Age estimation based on AAR in purified elastin from arteries may be a valuable additional tool in the identification of unidentified cadavers, especially in cases where other methods cannot be applied (e.g., no available teeth and body parts).

Assessment of nasal obstruction with rhinomanometry and subjective scales and outcomes of surgical and medical treatment.

Science.gov (United States)

Lara-Sánchez, Hugo; Álvarez Nuño, Candelas; Gil-Carcedo Sañudo, Elisa; Mayo Iscar, Agustín; Vallejo Valdezate, Luis Ángel

Prospective study of patients with nasal obstruction (NO) in order to measure therapeutic success by anterior active rhinomanometry (AAR), Nasal Obstruction Symptom Evaluation (NOSE) scale and Visual Analogue Scale (VAS) and to establish the correlation between these tests. Patients with NO, on whom we performed an AAR, NOSE and VAS scales at baseline and after medical treatment (topical nasal steroid) or surgery (septoplasty, turbinoplasty or septoplasty and turbinoplasty). The nasal flow obtained by the AAR and the score of both subjective scales (NOSE and VAS) were compared and analyzed. A total of 102 patients were included in the study. Surgical treatment resulted in statistically significant differences with the AAR and the subjective scales. While in patients with medical treatment there was an increase in the AAR nasal flow but without statistical significance (P=.1363). The correlation between the AAR, the NOSE and VAS scales was measured finding a strong correlation between the NOSE and VAS scales only (r=.83327). The patients with NO treated surgically have better results when these are evaluated by AAR or with subjective scales. There is no significant correlation between AAR, NOSE and VAS scales, this is considered to be because the AAR and subjective scales are complementary and measure different aspects of NO. The AAR and subjective scales are useful tools to be used together for the follow up of patients with NO. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.

Eestlaste loodud tehisintellekt lahendas ameeriklaste tasemetöö

Index Scriptorium Estoniae

2016-01-01

Tartu ülikooli meeskond koosseisus informaatikadoktorant Tambet Matiisen ja arvutiteduse instituudi töötaja Tanel Pärnamaa, saavutas tehisintellekti võistlusel Allen AI Science Challenge neljanda koha

Calibration of amino acid racemization (AAR) kinetics in United States mid-Atlantic Coastal Plain Quaternary mollusks using 87Sr/ 86Sr analyses: Evaluation of kinetic models and estimation of regional Late Pleistocene temperature history

Science.gov (United States)

Wehmiller, J.F.; Harris, W.B.; Boutin, B.S.; Farrell, K.M.

2012-01-01

The use of amino acid racemization (AAR) for estimating ages of Quaternary fossils usually requires a combination of kinetic and effective temperature modeling or independent age calibration of analyzed samples. Because of limited availability of calibration samples, age estimates are often based on model extrapolations from single calibration points over wide ranges of D/L values. Here we present paired AAR and 87Sr/ 86Sr results for Pleistocene mollusks from the North Carolina Coastal Plain, USA. 87Sr/ 86Sr age estimates, derived from the lookup table of McArthur et al. [McArthur, J.M., Howarth, R.J., Bailey, T.R., 2001. Strontium isotopic stratigraphy: LOWESS version 3: best fit to the marine Sr-isotopic curve for 0-509 Ma and accompanying Look-up table for deriving numerical age. Journal of Geology 109, 155-169], provide independent age calibration over the full range of amino acid D/L values, thereby allowing comparisons of alternative kinetic models for seven amino acids. The often-used parabolic kinetic model is found to be insufficient to explain the pattern of racemization, although the kinetic pathways for valine racemization and isoleucine epimerization can be closely approximated with this function. Logarithmic and power law regressions more accurately represent the racemization pathways for all amino acids. The reliability of a non-linear model for leucine racemization, developed and refined over the past 20 years, is confirmed by the 87Sr/ 86Sr age results. This age model indicates that the subsurface record (up to 80m thick) of the North Carolina Coastal Plain spans the entire Quaternary, back to ???2.5Ma. The calibrated kinetics derived from this age model yield an estimate of the effective temperature for the study region of 11??2??C., from which we estimate full glacial (Last Glacial Maximum - LGM) temperatures for the region on the order of 7-10??C cooler than present. These temperatures compare favorably with independent paleoclimate information

Kahtlased sõprussuhted = Dubious friendships / Ulrike Gerhardt

Index Scriptorium Estoniae

Gerhardt, Ulrike, 1984-

2014-01-01

Kohaspetsiifiline Läti, Leedu, Eesti, Saksamaa ja Rootsi ühisnäitus "(Re)construction of frendship" Riia Nurgamajas (endine riikliku julgeolekukomitee peakorter). Installatsiooniga "No borders" esines Tanel Rander Eestist

Hula Black - Eesti haute couture / Maria Ulfsak

Index Scriptorium Estoniae

Ulfsak, Maria, 1981-

2003-01-01

Esitleti uut Hula noortekomplekti Black, mille autorid on Anu Lensmant, Marit Ahven, Reet Ulfsak, Eve Hanson, Ruta Tepp, Ketlin Bachmann ja ehtekunstnikud Andrus Rumm, Julia-Maria Pihlak, Tanel Veenre

Interdependence, Reflexivity, Fidelity, Impedance Matching, and the Evolution of Genetic Coding

Science.gov (United States)

Carter, Charles W; Wills, Peter R

2018-01-01

Abstract Genetic coding is generally thought to have required ribozymes whose functions were taken over by polypeptide aminoacyl-tRNA synthetases (aaRS). Two discoveries about aaRS and their interactions with tRNA substrates now furnish a unifying rationale for the opposite conclusion: that the key processes of the Central Dogma of molecular biology emerged simultaneously and naturally from simple origins in a peptide•RNA partnership, eliminating the epistemological utility of a prior RNA world. First, the two aaRS classes likely arose from opposite strands of the same ancestral gene, implying a simple genetic alphabet. The resulting inversion symmetries in aaRS structural biology would have stabilized the initial and subsequent differentiation of coding specificities, rapidly promoting diversity in the proteome. Second, amino acid physical chemistry maps onto tRNA identity elements, establishing reflexive, nanoenvironmental sensing in protein aaRS. Bootstrapping of increasingly detailed coding is thus intrinsic to polypeptide aaRS, but impossible in an RNA world. These notions underline the following concepts that contradict gradual replacement of ribozymal aaRS by polypeptide aaRS: 1) aaRS enzymes must be interdependent; 2) reflexivity intrinsic to polypeptide aaRS production dynamics promotes bootstrapping; 3) takeover of RNA-catalyzed aminoacylation by enzymes will necessarily degrade specificity; and 4) the Central Dogma’s emergence is most probable when replication and translation error rates remain comparable. These characteristics are necessary and sufficient for the essentially de novo emergence of a coupled gene–replicase–translatase system of genetic coding that would have continuously preserved the functional meaning of genetically encoded protein genes whose phylogenetic relationships match those observed today. PMID:29077934

ISEA2004 fashion show

Index Scriptorium Estoniae

2004-01-01

Karolin Kuusiku, Vassilissa, Jaana Päeva ja Jaanika Pajuste moelooming Rahvusvahelise elektroonilise kunsti sümpoosioni ISEA2004 moeetendusel klubis Bon Bon (Tallinn). ISEA2004 moeetenduse koordinaatoriks oli Tanel Veenre

Läbipaistva saunaga Austraalias / Sandra Jõgeva

Index Scriptorium Estoniae

Jõgeva, Sandra, 1976-

2010-01-01

Kunstnike grupp Art Container osales Brisbane'i teatrifestivalil (4.-25. sept. 2010) interaktiivse etenduse ja saunainstallatsiooniga "Kümblejad" (autorid Tanel Saar, Erik Alalooga, Sandra Jõgeva, Janno Bergmann, Hans-Gunter Lock)

Animaalne antimagnetism / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2009-01-01

Rahvusvaheline grupinäitus "Loomakari" Tallinna Kunstihoones kuni 12. aprillini. Kuraator Sandra Jõgeva, kujundaja Tanel Saar. Lühidalt Jenni Juulia Wallinheimo, Kjetil Kauslandi ja Loore Emilie Raavi töödest

"Tõeline ukrainlane räägib ukraina keelt." = "A true ukrainian speaks ukrainian" / Šelda Puķīte

Index Scriptorium Estoniae

Puķīte, Šelda

2016-01-01

Rahvusvaheline rühmanäitus "Identiteet. Ebamäärasuse eesriide taga" Ukraina Rahvuslikus Kunstimuuseumis Kiievis. Kuraator Solvita Krese (Läti). Eestist osalesid Tanel Rander, Kristina Norman ja Flo Kasearu

Geophysical Investigation of Upper Mantle Anomalies of the Australian-Antarctic Ridge

Science.gov (United States)

Park, S. H.; Choi, H.; Kim, S. S.; Lin, J.

2017-12-01

Australian-Antarctic Ridge (AAR) is situated between the Pacific-Antarctic Ridge (PAR) and Southeast Indian Ridge (SEIR), extending eastward from the Australian-Antarctic Discordance (AAD). Much of the AAR has been remained uncharted until 2011 because of its remoteness and harsh weather conditions. Since 2011, four multidisciplinary expeditions initiated by the Korea Polar Research Institute (KOPRI) have surveyed the little-explored eastern ends of the AAR and investigated the tectonics, geochemistry, and hydrothermal activity of this intermediate spreading system. Recent isotope studies using the new basalt samples from the AAR have led to the new hypothesis of the Southern Ocean mantle domain (SOM), which may have originated from the super-plume activity associated with the Gondwana break-up. In this study, we characterize the geophysics of the Southern Ocean mantle using the newly acquired shipboard bathymetry and available geophysical datasets. First, we computed residual mantle Bouguer gravity anomalies (RMBA), gravity-derived crustal thickness, and residual topography along the AAR in order to obtain a geological proxy for regional variations in magma supply. The results of these analyses revealed that the southern flank of the AAR is associated with shallower seafloor, more negative RMBA, thicker crust, and/or less dense mantle in comparison to the conjugate northern flank. Furthermore, this north-south asymmetry becomes more prominent toward the central ridge segments of the AAR. Interestingly, the along-axis depths of the entire AAR are significantly shallower than the neighboring ridge systems and the global ridges of intermediate spreading rates. Such shallow depths are also correlated with regional negative geoid anomalies. Furthermore, recent mantle tomography models consistently showed that the upper mantle (< 250 km) below the AAR has low S-wave velocities, suggesting that it may be hotter than the nearby ridges. Such regional-scale anomalies of the

Kaos ja kord abstraktses kunstis / Vappu Thurlow

Index Scriptorium Estoniae

Thurlow, Vappu, 1960-

2005-01-01

Inglise füüsik Richard Taylor Jackson Pollocki maalidest. Kaose poolt mahajäetud mustritest ehk fraktaalidest. Siim Tanel Annuse reljeefmaalid, Andrus Rõugu abstraktsed vormid. Näitus "Pidulikud kontseptsioonid" Estonia Kontserdisaalis

BBC filmib Eestimaa eurolauluhullustust / Aarne Mäe

Index Scriptorium Estoniae

Mäe, Aarne, 1967-

2002-01-01

BBC salvestas dokumentaalfilmi tarvis Rakvere Teatri kohvikus Eurovisiooni lauluvõistluse võitnud Tanel Padarit ja tema ansamblit Speed Free. Filmi režissöör on Marina Zeldovich, produtsent Celia Quartiermain

Eesti saab kaasaegse veiste kogumise keskuse / Lii Sammler ; kommenteerinud Aldo Vaan

Index Scriptorium Estoniae

Sammler, Lii, 1963-

2016-01-01

Oktoobris avab Eesti Tõuloomakasvatajate Ühistu Harjumaal Kaunissaares loomade kogumiskeskuse. See annab võimaluse loomad enne eksporti kokku koondada ja vajalikud uuringud teha. Vestlusest Eesti Tõuloomakasvatajate Ühistu juhatuse esimehe Tanel Bulitkoga

Raju rokk ja rütmikas pop / Signe Sillasoo

Index Scriptorium Estoniae

Sillasoo, Signe

2009-01-01

Festivalist "Rabarock" 12.-13. juunil Järvakandis, erinevates Eesti linnades toimuvast kontserdituurist "Noored on hukas", kus esinemas Tanel Padar & The Sun ja Singer Vinger, kontserdil Viljandis 17. juunil esinevad Dingo, Smilers ja Traffic

Venezia filmifestivali kimbutab staaripõud / Triin Tael

Index Scriptorium Estoniae

Tael, Triin

2008-01-01

Algas Veneetsia 65. filmifestival. Tanel Toomi lühimängufilm "Teine tulemine" on võetud Veneetsia filmifestivali lühifilmide programmi. Sellest sõnum "Eesti linateos võistleb lühifilmide programmis"

BBC filmib Eesti elu pärast võitu Eurovisioonil / Aarne Mäe

Index Scriptorium Estoniae

Mäe, Aarne, 1967-

2002-01-01

BBC teeb dokumentaalfilmi ning salvestas Rakvere Teatri kohvikus Eurovisiooni lauluvõistluse võitnud Tanel Padarit ja tema ansamblit Speed Free. Filmi režissöör on Marina Zenovich, produtsent Celia Quartiermain

Muutused transiidis panid uusi lahendusi otsima / Roger Allas

Index Scriptorium Estoniae

Allas, Roger

2008-01-01

Transiidikonverentsil Transestonia tehti kokkuvõte 2007. aasta transiidimahtudest ja otsiti lahendusi tulevikuks. Vt. samas: Tanel Raig. Juhtparteid vaatavad transiidi arendamisel eri suundades; Isamaa ja Res Publica Liidu kommentaar transiidi ja konteinerterminali rajamise kohta

Plaadid / Kaur Garshnek, Ave Randviir, Priit Pruul...[jt.

Index Scriptorium Estoniae

2007-01-01

Uutest heliplaatidest Jaak Sooäär, Raul Vaigla, Tanel Ruben "No99 Jazzklubis", Black Strobe "Burn Your Own Church", The Quantic Soul Orchestra "Tropidelico", Uni "Kosmikud II", Bugge Wesseltoft "IM", Gabrielle "Always"

Temporal and spatial characteristics of the area at risk investigated using computed tomography and T1-weighted magnetic resonance imaging

DEFF Research Database (Denmark)

van der Pals, Jesper; Hammer-Hansen, Sophia; Nielles-Vallespin, Sonia

2015-01-01

AIMS: Cardiovascular magnetic resonance (CMR) imaging can measure the myocardial area at risk (AAR), but the technique has received criticism for inadequate validation. CMR commonly depicts an AAR that is wider than the infarct, which in turn would require a lateral perfusion gradient within...... and fluorescent microparticle pathology were used to investigate the AAR in a canine model (n = 10) of ischaemia and reperfusion. AAR size by CMR correlated well with CT (R(2) = 0.80), microsphere blood flow (R(2) = 0.80), and pathology (R(2) = 0.74) with good limits of agreement [-0.79 ± 4.02% of the left.......05 ± 0.02 mL/g/min, lateral vs. core, P = 0.001). The transmural extent of MI was lower in the lateral portion of the AAR than the core (28.2 ± 10.2 vs. 17.4 ± 8.4% of the wall, P = 0.001). CONCLUSION: T1-weighted CMR accurately quantifies size of the AAR with excellent agreement compared with three...

Muusikamaailm / Priit Kuusk

Index Scriptorium Estoniae

Kuusk, Priit, 1938-

2011-01-01

Lühisõnumeid muusikamaailmast: Gramophone auhind aastal 2011. Daniel Barenboim La Scala muusikadirektoriks. Lera Auerbachi loomingu esmaettekandeid sügisel. Valmis Ameerika sümfooniate uus diskograafia. Tanel Joamets tutvustab "Põhjamaa piltides" Tubina muusikat

Pop / Mart Juur

Index Scriptorium Estoniae

Juur, Mart, 1964-

2003-01-01

Heliplaatidest: Dave Gahan "Paper Monsters", Paddy McAloon "I Trawl the Megahertz", Jukka Gustavson Organ Fusion Band "Between Fire And Ice", Tanel Ruben & Victoria "A Sentimental Call", Opiate "Sometimes", The Mooney Suzuki "Electric Sweat"

Free-flying dynamics and control of an astronaut assistant robot based on fuzzy sliding mode algorithm

Science.gov (United States)

Gao, Qing; Liu, Jinguo; Tian, Tongtong; Li, Yangmin

2017-09-01

Space robots can perform some tasks in harsh environment as assistants of astronauts or substitutions of astronauts. Taking the limited working time and the arduous task of the astronauts in the space station into account, an astronaut assistant robot (AAR-2) applied in the space station is proposed and designed in this paper. The AAR-2 is achieved with some improvements on the basis of AAR-1 which was designed before. It can exploit its position and attitude sensors and control system to free flight or hover in the space cabin. And it also has a definite environmental awareness and artificial intelligence to complete some specified tasks under the control of astronauts or autonomously. In this paper, it mainly analyzes and controls the 6-DOF motion of the AAR-2. Firstly, the system configuration of AAR-2 is specifically described, and the movement principles are analyzed. Secondly, according to the physical model of the AAR-2, the Newton - Euler equation is applied in the preparation of space dynamics model of 6-DOF motion. Then, according to the mathematical model's characteristics which are nonlinear and strong coupling, a dual closed loop position and attitude controller based on fuzzy sliding mode control is proposed and designed. Finally, simulation experiments are appropriate to provide for AAR-2 control system by using Matlab/Simulink. From the simulation results it can be observed that the designed fuzzy sliding mode controller can control the 6-DOF motion of AAR-2 quickly and precisely.

19. II esitas HULA Kanuti gildi vaatemängulist kostüümidraamat

Index Scriptorium Estoniae

2003-01-01

Rõivakollektsiooni autorid on HULA loojad Reet Ulfsak, Marit Ahven, Anu Lensment, Eve Hanson ning külalistena Ruta Tepp, Ketlin Bachmann. HB kollektsiooni jaoks disainitud ehete autorid on Tanel Veenre, Andrus Rumm, Julia-Maria Pihlak

Moda opjat vernulas v Tallinn - Fashion Is Back In Tallinn

Index Scriptorium Estoniae

2008-01-01

Moeüritus Fashion is Back in Tallinn (FIBIT) Viru Keskuses Tallinnas. Gala-etendusel "Sinine, Must ja Valge" esitletud Anu Samarüütel-Longi, Tanel Veenre ja Arne Niidu moekollektsioonidest. Lisaks värvilised fotod

RILEM recommendations for the prevention of damage by alkali-aggregate reactions in new concrete structures state-of-the-art report of the RILEM technical committee 219-ACS

CERN Document Server

Sims, Ian

2016-01-01

This book contains the full set of RILEM Recommendations which have been produced to enable engineers, specifiers and testing houses to design and produce concrete which will not suffer damage arising from alkali reactions in the concrete. There are five recommended test methods for aggregates (designated AAR-1 to AAR-5), and an overall recommendation which describes how these should be used to enable a comprehensive aggregate assessment (AAR-0). Additionally, there are two Recommended International Specifications for concrete (AAR-7.1 & 7.2) and a Preliminary International Specification for dams and other hydro structures (AAR-7.3), which describe how the aggregate assessment can be combined with other measures in the design of the concrete to produce a concrete with a minimised risk of developing damage from alkali-aggregate reactions.

Absurd ja lootus Albert Camus' lühiproosas / Aivar Kull

Index Scriptorium Estoniae

Kull, Aivar, 1955-

2004-01-01

Arvustus: Camus, Albert. Pagendus ja kuningriik : kogutud lühiproosa / prantsuse keelest tõlkinud Triinu Tamm, Krista Vogelberg, Tanel Lepsoo, Henno Rajandi. Tallinn : Varrak, 2004. Vaata ka: Kull, Aivar. Kulli pilk. - Tartu : Ilmamaa, 2005, lk. 78-79

"Matrix" sobitub iga filosoofiaga / Rando Tooming

Index Scriptorium Estoniae

Tooming, Rando

2003-01-01

Andy ja Larry Wachowski ulmefilmide triloogia "Matrix" fenomeni analüüsist ajakirja "Vikerkaar" 2003. aasta 9. numbris, kus sellele on pühendatud nelja filosoofi artiklid ( Slavoj Zhizhek, Jüri Eintalu, Bruno Mölder, Tanel Tammet)

Plaadid / Veiko Pesur, Tiiu Laks, Mart Normet

Index Scriptorium Estoniae

Pesur, Veiko

2008-01-01

Uutest heliplaatidest Shower, Nice Try ja Jim Arrow & The Anachrones "Eesti Rock Antoloogia", Eskimo "Psst! pole sõnu sõnumiks tarvis", Tanel Padar & The Sun "Veidi valjem kui vaikus II", Liisi Koikson "Väikeste asjade võlu"

München 2006 : Ehe / Kadri Mälk

Index Scriptorium Estoniae

Mälk, Kadri, 1958-

2006-01-01

Münchenis igal kevadel toimuvast ehtesündmusest "Schmuckszene" ehk "Ehtelava". 2006. aastal said preemiad Annamaria Zanella Itaaliast, Annelies Planteijdt Hollandist ja Bernhard Schobinger Šveitsist. Eestit esindasid Piret Hirve ja Tanel Veenre tööd

Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455

Directory of Open Access Journals (Sweden)

Stefania Gessi

2017-12-01

Full Text Available Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A1, A2A, A2B, and A3 receptor (AR subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell proliferation depending on the engagement of different receptor subtypes in various tumors. The involvement of A2AARs in human A375 melanoma, as well as in human A549 lung and rat MRMT1 breast carcinoma proliferation has been evaluated in view of the availability of a novel A2AAR antagonist, with high affinity and selectivity, named as 2-(2-furanyl-N5-(2-methoxybenzyl[1,3]thiazolo[5,4-d]pyrimidine-5,7-diammine (TP455. Specifically, the signaling pathways triggered in the cancer cells of different origin and the antagonist effect of TP455 were investigated. The A2AAR protein expression was evaluated through receptor binding assays. Furthermore, the effect of A2AAR activation on cell proliferation at 24, 48 and 72 hours was studied. The selective A2AAR agonist 2-p-(2-carboxyethylphenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride (CGS21680, concentration-dependently induced cell proliferation in A375, A549, and MRMT1 cancer cells and the effect was potently antagonized by the A2AAR antagonist TP455, as well as by the reference A2AAR blocker 4-(2-[7-amino-2-(2-furyl[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethylphenol (ZM241385. As for the signaling pathway recruited in this response we demonstrated that, by using the specific inhibitors of signal transduction pathways, the effect of A2AAR stimulation was induced through phospholipase C (PLC and protein kinase C-delta (PKC-δ. In addition, we evaluated, through the AlphaScreen SureFire phospho(p protein assay, the kinases enrolled by A2AAR to stimulate cell proliferation and we found the involvement of protein kinase B (AKT, extracellular regulated kinases (ERK1/2, and c-Jun N-terminal kinases (JNKs. Indeed, we demonstrated that the CGS21680 stimulatory effect on kinases was

Viljandi laululava = Viljandi festival arena

Index Scriptorium Estoniae

2015-01-01

Viljandi laululava Talli tänav 2, valminud 2013. Arhitektid Ott Kadarik, Mihkel Tüür, Tanel Trepp (Kadarik Tüür Arhitektid OÜ), insenerid Tõnu Peipman, Viljar Sepp (IB Printsiip OÜ). Eesti Kultuurkapitali Arhitektuuri sihtkapitali aastapreemia 2014

25-Hydroxyvitamin D, IL-31, and IL-33 in Children with Allergic Disease of the Airways

Directory of Open Access Journals (Sweden)

Anna Bonanno

2014-01-01

Full Text Available Low vitamin D is involved in allergic asthma and rhinitis. IL-31 and IL-33 correlate with Th2-associated cytokines in allergic disease. We investigated whether low vitamin D is linked with circulating IL-31 and IL-33 in children with allergic disease of the airways. 25-Hydroxyvitamin D [25(OH Vit D], IL-31, and IL-33 plasma levels were measured in 28 controls (HC, 11 allergic rhinitis (AR patients, and 35 allergic asthma with rhinitis (AAR patients. We found significant lower levels of 25(OH Vit D in AR and in AAR than in HC. IL-31 and IL-33 plasma levels significantly increased in AAR than HC. IL-31 and IL-33 positively correlated in AR and AAR. 25(OH Vit D deficient AAR had higher levels of blood eosinophils, exacerbations, disease duration, and total IgE than patients with insufficient or sufficient 25(OH Vit D. In AAR 25(OH Vit D levels inversely correlated with total allergen sIgE score and total atopy index. IL-31 and IL-33 did not correlate with 25(OH Vit D in AR and AAR. In conclusion, low levels of 25(OH Vit D might represent a risk factor for the development of concomitant asthma and rhinitis in children with allergic disease of the airways independently of IL-31/IL-33 Th2 activity.

Plaadid / Mart Normet

Index Scriptorium Estoniae

Normet, Mart, 1979-

2006-01-01

Uutest heliplaatidest Tõnis Mägi "Vestlus Hermanniga", Tanel Padar & The Sun "Veidi valjem kui vaikus", Solveig Slettahjell & Slow Motion Quartet "Pixiedust", "Brokeback Mountain", "Lindström & Prins Thomas", Pia Fraus "Nature Heart Software", Richard Ashcroft "Keys To The World"

Fantacy't erinevale maitsele / Sash Uusjärv

Index Scriptorium Estoniae

Uusjärv, Sash

2011-01-01

Arvustus: Westerfeld, Scott. Inetud / inglise keelest tõlkinud Maali Käbin. Tallinn : Varrak, 2011; Flinn, Alex. Koletu / inglise keelest tõlkinud Kret Kaasik. Tallinn : Varrak, 2010 ; Banner, Catherine. Kuninga silmad / inglise keelest tõlkinud Tanel Rõigas. Tallinn : Varrak, 2011

Valmib valus lavalugu perest : Athenas jõuab vaatajate ette Mart Kivastiku suhtedraama / Raimu Hanson

Index Scriptorium Estoniae

Hanson, Raimu, 1957-

2008-01-01

SA Eesti Teatri Festival esietendab 4. mail Athena keskuses Margus Kasterpalu lavastuses Mart Kivastiku näidendit "Meie isa, kes sa oled ..." Mängivad Vanemuise näitlejad Marika Aidla, Hannes Kaljujärv, Tanel Jonas ning Leino Rei

Eesti foto Berliinis

Index Scriptorium Estoniae

2003-01-01

Berliinis Giedre Bartelti galeriis kaheksa eesti kunstniku fotonäitus "(Un)Dressed Body in the Baltic Photo Art vol. 2 : Estonia" - Ene-Liis Semper, Peeter Laurits, Mark Raidpere, Liina Siib, Ly Lestberg, Mare Tralla, Margot Kask ja Tanel Veenre

Vanadusest infantiilsuseni / Teet Veispak

Index Scriptorium Estoniae

Veispak, Teet, 1955-

2005-01-01

Aprillikuu näitustest Tallinnas. Pikemalt Reet Varblase kureeritud näitusest "Homo grandis natu" Tallinna Kunstihoones, Jaan Paavle ja Tanel Saare näitustest Draakoni galeriis, Külli K. Kaatsi ja Daniele Mosca väljapanekust "Salajased aiad" Kunstihoone galeriis

Absurd on igihaljas / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2006-01-01

Tutvustus: Camus, Albert. Õnnelik surm / tõlkinud Tanel Lepsoo. Tallinn : Varrak, 2005 ; Metsanurk, Mait. Kreeps / koost. Maire Liivamets. Tallinn : Eesti Raamat, 2005. (Eesti novellivara). Järg: 23. veebr., lk. 27, sisaldab Aivar Kulli kriitikakogu "Kulli pilk" (Ilmamaa, 2005) tutvustust

FIBIT : k patriotizmu tsherez kubizm i gotiku / Olesja Truvorova

Index Scriptorium Estoniae

Truvorova, Olesja

2008-01-01

Moeshõul "Sinine, Must ja Valge" esitletud Anu Samarüütel-Longi, Tanel Veenre ja Arne Niidu moekollektsioonidest. Etendus toimus moeüritusel Fashion is Back in Tallinn (FIBIT) Viru Keskuses Tallinnas. Lisaks värvilised fotod Stanislav Rõshkevitshilt

11. IV avati Draakoni galeriis...

Index Scriptorium Estoniae

2005-01-01

Tanel Saare (sünd. 1979) näitus "Gott und huhn episode IV: seed shower". Eksponeeritakse väljavõtteid aktsioonidest aastatel 2000-2004 Turus, Nürnbergis, Berliinis, Lohusalus ja Soulis. Osa aktsioone toimus koos rühmitusega Non Grata

1 küsimus noorele juhile : Mis teha, kui kopp on ees - kuidas sa stressist jagu saad? / Riho Jürvetson, Merit Miller, Krister Rekkaro ... [jt.

Index Scriptorium Estoniae

2009-01-01

Küsimusele vastavad EMT erakliendi osakonna juhataja Riho Jürvetson, KPMG Baltics müügijuht Merit Miller, ArtPrint juht Krister Rekkaro, Dateli juhatuse liige Triin Sepp, Media House projektijuht Tanel Tarkmees, Ober-Haus Kinnisvara tegevjuht Katrin Klein-Näppi

Münchenis esitletakse Eesti juveelikunsti

Index Scriptorium Estoniae

2009-01-01

Münchenis toimuval üritusel Schmuckzene esitletakse raamatut "Just Must", mis ilmus 2008. aastal Tallinnas samanimelise ehtekunstinäituse raames. Koostaja Kadri Mälk, kujundaja Aadam Kaarma, fotod Tanel Veenre. Kirjastus Arnoldsche Art Publishers arvas raamatu aasta viie parema ehtekunstiraamatu hulka

Popmuusika / Margus Haav

Index Scriptorium Estoniae

Haav, Margus, 1969-

2006-01-01

Uutest heliplaatidest Nelly Furtado "Loose", Nouvelle Vague "Bande A Part", Fatboy Slim "The Greatet Hits", Plan B "Who Needs Actions When You Got Words", Linus Loves "Stage Invader", Tanel Padar & The sun "100% Rock'nRoll2, George Benson "The Essential"

Raamat / Tanel Verk

Index Scriptorium Estoniae

Verk, Tanel

2007-01-01

Dirigent Neeme Järvi elulooalbumi "Neeme Järvi. Kunstniku elu / The Maestro's Touch" esitlusest Tallinnas Viru Keskuse raamatupoes Rahva Raamat, pidulikust albumi esitlusest 15. aug. Eesti Teatri- ja Muusikamuuseumis

Kõlaritootja hoiab omaette / Andris Feldmanis

Index Scriptorium Estoniae

Feldmanis, Andris, 1982-

2005-01-01

Ilmunud ka: Delovõje Vedomosti 16. veebr. lk. 12. Kvaliteetkõlarite tootja Audes LLC OÜ börsileminekule ei mõtle. Diagramm: Audese käive nelja aastaga kahekordistunud. Kommenteerib Tõnis Oja. Vt. samas: Tanel Kompus. Audese kvaliteet on aastaga tõusnud

Ellujäämiskursus / interv. Sandra Jõgeva

Index Scriptorium Estoniae

2008-01-01

Non Grata Kunstikonteineris kuni 17. XI näitus "Dekonstruktsioon/Rekonstruktsioon", Orion Maxtedi ja Tanel Saare workshop'i jäädvustus. Workship'is osalesid performance'i-kunstnikud Beth Greenhalgh, Samuel Hasler, Yoko Ishiguro, maalikunstnik Josephine Wood, helikunstnik Simon Whetham ja Sandra Jõgeva

Ehe linnulennult. Kõikjal. Eikusagil / Kristiina Laurits

Index Scriptorium Estoniae

Laurits, Kristiina, 1975-

2005-01-01

Ehtekunstinäitus "Ars Ornata Europeana 2005" Lissaboni antiikkunsti muuseumis (Museu Nacional de Arte Antiga) 7. VII-11. IX ja Belemi kultuurikeskuses 5. VII-4. IX. Esinema oli kutsutud ehtekunstnikke üle maailma, Eestist olid näitusele valitud Tanel Veenre linnupea-kaelaehted

7. I kell 18 avatakse Pärnu Muuseumi Aidas...

Index Scriptorium Estoniae

2006-01-01

Urmas Viigi juhendatud EKA graafikaüliõpilaste tööde näitus, toimuvad ka Pink Pungi, Ernest Truely, Lexxxa, Ville-Karel Viirelaiu, Egle Veske, Remo Randveri, Toomas Kuusingu, Meeland Sepa, Sorge, Sirami (Mari Kartau), Billeneeve, Tanel Saare performance'id

Kirjad Paduasse / Marijke Vallanzasca ; tõlkinud Mart Rummo

Index Scriptorium Estoniae

Vallanzasca, Marijke

2010-01-01

Eesti ehtekunstinäitus Marijke Studios Paduas 23. 04.-30. 06. 2010. 17 osalejat loetletud. Eksponeeritud oli 69 ehteobjekti, ilmus kataloog. Kadri Mälgu, Piret Hirve, Tanel Veenre, Villu Plingi, Eve Margus-Villemsi, Kristiina Kibe ja Kertu Tubergi töödest

Kontsert

Index Scriptorium Estoniae

2005-01-01

Elleri Tartu Muusikakooli trompetistide kontserdist 31. märtsil ja Tanel Joametsa klaverikontserdist 3. apr.TÜ aulas. Osiris Piano Trio kontserdist 1. apr. TÜ Ajaloo Muuseumis. Kontserdist 26. märtsil Vanemuise kontserdimajas. Camerata Scotland kontserdist Christopher Adey juhatusel 6. apr. Vanemuise kontserdimajas

Ehtekunstnikud Genfis

Index Scriptorium Estoniae

2002-01-01

Eesti Kunstiakadeemia ehteväljapanek kõrgkoolide ehetekunstiüliõpilaste suursündmusel "L'ornament est-il toujours un crime?". Eksponeeritud Tanel Veenre, Bruno Lillemetsa, Julia Maria Pihlaku, Kertu Tubergi, Villu Plingi, Piret Hirve ja Eve Margus-Villemsi tööd

Korgipuu uued viljad / Tõnis Malkov

Index Scriptorium Estoniae

Malkov, Tõnis

2008-01-01

Rahvusvaheline ehtekunsti rändnäitus "2nd SKIN. Korgipuust ehted" Eesti Tarbekunsti- ja Disainimuuseumis. Eestist osalevad Kadri Mälk, Tanel Veenre. Kunstnike Carla Castiajo, Leonor Hipolito, Ramon Puig Cuyase, Eija Mustoneni, Theo Smeetsi, Manuel Vilhena, Pedro Segueira töödest

Hõivatute edetabelisse jõudis kolm meest Ugalast / Tea Raidsalu

Index Scriptorium Estoniae

Raidsalu, Tea

2009-01-01

Postimehe nädalalõpulisa "Arter" kõige hõivatumate näitlejate loendis on Ugalast Tanel Ingi, Arvo Raimo ja Arvi Mägi. Andmeid nimekirja koostamiseks andsid teatrite trupijuhid. Ugala näitlejate kaalukamate rollide väljaselgitamist kommenteerib kirjandustoimetaja Helle Leppik

Brno graafilise disaini biennaal

Index Scriptorium Estoniae

2008-01-01

17. VI-19. X 2008 avatud 23. Brno rahvusvahelisest graafilise disauini biennaalist "What's next in graphic design?". Tanel Kärp toob positiivsete näidetena Brno näitusele jõudnud Mart Andersoni Humala ja Kristjan Jagomäe Enigma kirjatüübid

Pop / Mart Kuldkepp

Index Scriptorium Estoniae

Kuldkepp, Mart

2008-01-01

Heliplaatidest: James "Hey Ma", Kelder "Vikerkaar ja latimeeria", David Torn "Lars and the Real Girl. Music from the motion picture", Tanel Ruben "Kogutud rikkus", Neon Neon "Stainless Style", 3 Doors Down "3 Doors Down", Winston Tong "In a Manner Of Speaking (Best Of)", Witch "Paralyzed"

Genetics Home Reference: Wolff-Parkinson-White syndrome

Science.gov (United States)

... Davis AM, Drago F, Janousek J, Klein GJ, Law IH, Morady FJ, Paul T, Perry JC, Sanatani S, Tanel RE. PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in ...

Elu mütoloogilises psühhoruumis / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2009-01-01

Tutvustus: Lukjanenko, Sergei. Öine Vahtkond / tlk. Tanel Rõigas. Tallinn : Varrak, 2008 ; Rubina, Dina. Päikeselisel tänavapoolel / tlk. Veronika Einberg. Tallinn : Tänapäev, 2008 ; Suhhotšev, Aleksandr. Goa sündroom / tlk. Veronika Einberg. Tallinn : Tänapäev, 2008

Eesti ehe Hollandis

Index Scriptorium Estoniae

1999-01-01

12. dets.-ni Hollandis, Nijmegeni linnas Galeerie Marzees noorte eesti ehtekunstnike näitus 'Õhu lossid', mida on spondeerinud ka Charon Kransen New Yorgist. Esinevad Tanel Veenre, Katrin Sipelgas, Villu Plink, Kristiina Laurits, Piret Hirv, Eve Margus ning õppejõud Kadri Mälk

Kunst viib saunakultuuri maakera kuklapoolele

Index Scriptorium Estoniae

2010-01-01

Kultuuritehases Polymer tegutsev Art Container tutvustab Austraalias Brisbane'i festivalil eesti saunakultuuri. Eksponeeritakse arhitektuurilist installatsiooni (kasutatud akendest ehitatud läbipaistev saun) ja esitatakse interaktiivset performance'it "Kümblejad". Töö autorid on Erik Alalooga, Tanel Saar, Sandra Jõgeva, Janno Bergmann, Hans-Gunter Lock

Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation

International Nuclear Information System (INIS)

Eriksson, Olof; Carlsson, Fredrik; Blom, Elisabeth; Sundin, Anders; Långström, Bengt; Korsgren, Olle; Velikyan, Irina

2012-01-01

Introduction: Islet transplantation is a promising treatment for type 1 diabetes mellitus, but the fate of the cells after intraportal infusion is unclear. It is therefore imperative to develop novel techniques for noninvasive imaging and quantification of events following islet transplantation. Methods: Small islet-like microbeads, avidin-covered agarose resins (AARs), were used as a model system for islet transplantation. Capability for specific [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin uptake and retention for either AARs or human islets conjugated with avidin by means of a heparin scaffold was studied in vitro. Biodistribution of the novel positron emission tomography (PET) tracer [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin was evaluated in mice treated by intraportal transplantation of AARs by μPET/computed tomography and ex vivo organ distribution and compared with control mice. Results: AARs had high capability to bind [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin, close to 50% of administrated tracer/μl in vitro (>0.25 MBq/μl). Avidin-tagged human islets could bind on average 2.2% of administered tracer/μl. Specificity (>90%) and retention (>90% after 1 h) were high for both AARs and avidin-tagged islets. Hepatic tracer uptake and retention were increased in mice transplanted with AARs [standardized uptake value (SUV)=2.6] compared to the untreated group (SUV=1.4). In vivo uptake of tracer to AARs was blocked by preadministration of unlabeled biotin. Conclusions: Avidin-tagged islet-like objects can be tracked in hepatic volume after intraportal transplantation by using [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin and PET.

Eesti ehted Firenzes

Index Scriptorium Estoniae

2005-01-01

Galeriis Le Arti Orafe on avatud kuue nimeka Euroopa ehtekoolkonna näitus "Chroma". Eestist on töödega esindatud Andrus Rumm, Eve Margus-Villems, Julia-Maria Pihlak, Kertu Tuberg, Kristiina Laurits, Kärt Maran, Maarja Niinemägi, Merle Kasonen, Piret Hirv, Tanel Veenre

Arhitektuuripoliitiliselt Jõhvi kontserdimajast = Jõhvi concert house from the point of architecture policy / Ingrid Ruudi

Index Scriptorium Estoniae

Ruudi, Ingrid, 1978-

2006-01-01

Projekteerija: AB Luhse & Tuhal OÜ. Arhitektid Ra Luhse, Tanel Tuhal. Sisekujundus: Aivar Oja, Mareliis Raid. Konstruktor: IB Pike OÜ. Insener-akustik Linda Madalik. Ehitusfirma: AS YIT Ehitus. Projekt 2003, valmis 2005. Ill.: I ja II korruse plaan, lõige, välisvaade, 2 sisevaadet, värv

Vähem formaalsust, rohkem julgust ja enesekriitikat! / Marko Mäetamm, Anneli Porri, Tiit Pääsuke ... [jt.] ; intervjueerinud Reet Varblane

Index Scriptorium Estoniae

2009-01-01

Kunstiõpetamise võimalikkuse ja vajalikkuse üle vestlesid Eesti Kunstiakadeemia vabade kunstide teaduskonna dekaan Marko Mäetamm, fotokunsti osakonna õppejõud Anneli Porri, emeriitprofessor Tiit Pääsuke, prorektor Liina Siib, graafilise disaini osakonna õppejõud Indrek Sirkel ja ehtekunsti osakonna õppejõud Tanel Veenre

Chapter K: Progress in the Evaluation of Alkali-Aggregate Reaction in Concrete Construction in the Pacific Northwest, United States and Canada

Science.gov (United States)

Shrimer, Fred H.

2005-01-01

The supply of aggregates suitable for use in construction and maintenance of infrastructure in western North America is a continuing concern to the engineering and resources-management community. Steady population growth throughout the region has fueled demand for high-quality aggregates, in the face of rapid depletion of existing aggregate resources and slow and difficult permitting of new sources of traditional aggregate types. In addition to these challenges, the requirement for aggregates to meet various engineering standards continues to increase. In addition to their physical-mechanical properties, other performance characteristics of construction aggregates specifically depend on their mineralogy and texture. These properties can result in deleterious chemical reactions when aggregate is used in concrete mixes. When this chemical reaction-termed 'alkali-aggregate reaction' (AAR)-occurs, it can pose a major problem for concrete structures, reducing their service life and requiring expensive repair or even replacement of the concrete. AAR is thus to be avoided in order to promote the longevity of concrete structures and to ensure that public moneys invested in infrastructure are well spent. Because the AAR phenomenon is directly related to the mineral composition, texture, and petrogenesis of the rock particles that make up aggregates, an understanding of the relation between the geology and the performance of aggregates in concrete is important. In the Pacific Northwest, some aggregates have a moderate to high AAR potential, but many others have no or only a low AAR potential. Overall, AAR is not as widespread or serious a problem in the Pacific Northwest as in other regions of North America. The identification of reactive aggregates in the Pacific Northwest and the accurate prediction of their behavior in concrete continue to present challenges for the assessment and management of geologic resources to the owners and operators of pits and quarries and to the

Rein Taaramäe virutas protestiks liidrisärgi porri ja katkestas / Jaan Martinson

Index Scriptorium Estoniae

Martinson, Jaan, 1960-

2007-01-01

Velotuuri Tour de Le Pays Roannaisþ finishis jäi Rein Taaramäe koos klubikaaslaste Tanel Kangerti ja Kalle Kriidiga enne joont seisma, võttis seljast liidrisärgi ja viskas selle protestiks porri. Eestlased olid viimasel etapil suunatud valele teele, kuid kohtunik sõitu ei peatanud

Kunstimuuseumi viimane näitus Rotermanni soolalaos

Index Scriptorium Estoniae

2005-01-01

13. maist Marko Mäetamme ja Kaido Ole "Suur projekt". 18. V muusikaline live-keskkond "Museum of Sleep / Uinuv muuseum", hüvastijätt soolalaoga Ki wa, Joel Tammiku, Tanel Paliale, Masina, Porti, El Roboticos Digitablosi ja Fabrique'i ning Villu Jõgeva ja Kaarel Kurismaa objektide osavõtul

Vennad Coenid jäid seekord sootuks ilma / Kaarel Kressa

Index Scriptorium Estoniae

Kressa, Kaarel, 1983-

2011-01-01

Filmidest, mis kandideerisid mitmes kategoorias Oscarile, kuid ei saanud ühtki auhinda või said oodatust vähem auhindu. Eesti režissööri Tanel Toomi lühifilm "Pihtimus" kandideeris Oscarile parima lühifilmi kategoorias, võitis Luke Matheny "God of Love" (USA, 2010)

Kaheksakümnendad tulevad! / Margus Kiis

Index Scriptorium Estoniae

Kiis, Margus

2003-01-01

Rühmituse Fashist Lendas Üle (FLY) näitus Tartu lastekunstikooli galeriis kuni 30. VIII. Kuraator Andres Keil. Academia Grata üliõpilastest koosneva rühmituse programmist, näituse ava-performance-ist, Teet Raudsepa, Ville Kareli, Tanel Pälli, Taavo Raudsepa ja soomlase Veera Varteva maalidest

Punane moon või kaine mõistus / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2001-01-01

Nukuteatri uue hoone sisekujunduse võistluse I ja II koha töödest. I koha töö autorid Raivo Kotov ja Andrus Kõresaar, II koha töö autorid Ülar Mark, Liina Link, stilist Ain Nurmela ja arvutigraafik Tanel Viks büroost Mark & Tamm Arhitektid

Tulekul...

Index Scriptorium Estoniae

2008-01-01

Märtsis toimuvatest muusikaüritustest: Tudengijazz 2008, "Matteuse Passioon" kontsertidest, muusikafestivalist Maa ja Ilm, muusikafestivalist Soul Spectrum, harfimängijast Florence Sitruk. Tanel Padari ja ansambli The Sun kontserttuurist. Jazzkaare piletitemüügist. 14. märtsil toimuvast rootsi ansambli Koop kontserdist, rootsi muusikute Mats & Morgan kontsertidest

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2010-01-01

Lühisõnumeid filmimaailmast: Režissöör Terry Gilliami unistus ekraniseerida klassikateos "Don Quijote" nurjus. Ansambel Queenist hakatakse filmi tegema. "Kadunud paradiis" on tulekul. Lähiminevikus lahkunuid: Alain Corneau (7. aug. 1943 - 29. aug. 2010) ja Claude Chabrol (24. juuni 1930 - 12. sept. 2010)

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2010-01-01

Oliver Stone töödest. Charlie Chaplin virtuaalmaailmas. Lähiminevikus lahkunud: inglise-kanada filmiajaloolane ja -kriitik Robin Wood (23. II 1931 - 18. XII 2009), vene filmihelilooja Isaak Švarts (13. V 1923 - 27. XII 2009), prantsuse filmi- ja teatrilavastaja Eric Rohmer (4. IV 1920 - 11. I 2010)

Joonisfilmid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2005-01-01

Eesti Joonisfilm ja Nukufilm üllitasid firma V&K Holding kaudu kaks videokassetti "Armastuskolmnurgad" ja "Rebasenaine läheb taevasse" eesti noorte animaatorite Kaspar Jancise, Ülo Pikkovi ja Priit Tenderi loominguga

Eros / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Kolmest iseseisvast armastusloost koosnev episoodfilm "Eros" : režissöörid Wong Kar-Wai ("Käsi"), Steven Soderbergh ("Tasakaal" / "Equilibrium"), Michelangelo Antonioni ("Asjade ohtlik käik") : Hongkong - Hiina - USA - Prantsuse - Itaalia 2004

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2011-01-01

Lühisõnumeid filmimaailmast: Scorsesel valmib dokumentaalfilm George Harrisonist. Meirellesel uus mängufilm "360". Lähiminevikus lahkunuid: Gualtiero Jacopetti (4.09.1919 - 17. 08.2011), Raoul Ruiz (25.07.1941 - 19.08.2011), Ia Savvina (2.03.1938-27.08.2011)

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2009-01-01

Lühisõnumeid filmimaailmast: 21.- 30. augustini peetavast 20. rahvusvahelisest filmifestivalist "Espoo Cine"; Martin Scorsese hakkab tegema eluloofilmi Frank Sinatrast; Lahkus itaalia filmikriitik, dramaturg ja stsenarist Tullio Kezich (17. IX 1928 - 17. VIII 2009)

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2008-01-01

Lühisõnumid: Prantsuse kinodesse on jõudnud retrofilmid - "Couche, ühe inimese lugu" (koomik Michel Coluche'ist, rezh. Antoine de Gaunes; ), "Tapainstinkt" ja "Ühiskonna vaenlane nr 1" (mõlemad gangster Jacques Mesrine'ist, rezh. Jean-Francois Richet). Jean-Jacques Annaud' "Kashmir". Roomas triumfeeris "Resolution 819" (rezh. Giacomo Battiato). Humberto Solas (4. XII 1941 - 17. IX 2008)

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2009-01-01

Ameeriklase Rob Marshalli Fellini klassikafilmi "8 1/2" kaasajastatud versioon "Üheksa" ("Nine"). Nimekiri filmidest, millest võiks uusversioone luua. Lahkus vene filminäitleja Vjatšeslav Tihhonov

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2009-01-01

Woody Alleni uusimatest filmiprojektidest. Ingmar Bergmanni kodusaare Fårö tulevikust kunstiinimeste puhke- ja loomekoduna. Lahkunud on Mikheil Kalatozišvili (19. 05. 1959 - 12. 10. 2009) ja Rosanna Schiaffino (25. 11. 1939 - 17. 10. 2009)

Filmimaailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2010-01-01

Lühisõnumid filmimaailmast: Prantsusmaal käivitub keskkooliõpilastele mõeldud üleriigiline filmiõpe. James Nguyeni õudusfilm "Linnuepideemia: šokk ja terror" osutus keskpäraseks soperdiseks. Clint Eastwood ja mitmed tuntud filmiinimesed tähisatvad tänavu 80ndat sünnipäeva. Lahkus operaator William Lubtchansky

Psychophysiological Assessment in Pilots Performing Challenging Simulated and Real Flight Maneuvers.

Science.gov (United States)

Johannes, Bernd; Rothe, Stefanie; Gens, André; Westphal, Soeren; Birkenfeld, Katja; Mulder, Edwin; Rittweger, Jörn; Ledderhos, Carla

2017-09-01

The objective assessment of psychophysiological arousal during challenging flight maneuvers is of great interest to aerospace medicine, but remains a challenging task. In the study presented here, a vector-methodological approach was used which integrates different psychophysiological variables, yielding an integral arousal index called the Psychophysiological Arousal Value (PAV). The arousal levels of 15 male pilots were assessed during predetermined, well-defined flight maneuvers performed under simulated and real flight conditions. The physiological data, as expected, revealed inter- and intra-individual differences for the various measurement conditions. As indicated by the PAV, air-to-air refueling (AAR) turned out to be the most challenging task. In general, arousal levels were comparable between simulator and real flight conditions. However, a distinct difference was observed when the pilots were divided by instructors into two groups based on their proficiency in AAR with AWACS (AAR-Novices vs. AAR-Professionals). AAR-Novices had on average more than 2000 flight hours on other aircrafts. They showed higher arousal reactions to AAR in real flight (contact: PAV score 8.4 ± 0.37) than under simulator conditions (7.1 ± 0.30), whereas AAR-Professionals did not (8.5 ± 0.46 vs. 8.8 ± 0.80). The psychophysiological arousal value assessment was tested in field measurements, yielding quantifiable arousal differences between proficiency groups of pilots during simulated and real flight conditions. The method used in this study allows an evaluation of the psychophysiological cost during a certain flying performance and thus is possibly a valuable tool for objectively evaluating the actual skill status of pilots.Johannes B, Rothe S, Gens A, Westphal S, Birkenfeld K, Mulder E, Rittweger J, Ledderhos C. Psychophysiological assessment in pilots performing challenging simulated and real flight maneuvers. Aerosp Med Hum Perform. 2017; 88(9):834-840.

Cluster in the Auroral Acceleration Region

Science.gov (United States)

Pickett, Jolene S.; Fazakerley, Andrew N.; Marklund, Gorun; Dandouras, Iannis; Christopher, Ivar W.; Kistler, Lynn; Lucek, Elizabeth; Masson, Arnaud; Taylor, Matthew G.; Mutel, Robert L.;

Estconil jagati taas Stalkereid / Jüri Kallas

Index Scriptorium Estoniae

Kallas, Jüri

2006-01-01

Ulmeauhind Stalker 2006 - tõlkeromaan: Lukjanenko, Sergei. Peegelduste labürint / tõlkinud Tanel Rõigas; antoloogia või tõlkekogu: Arvi Nikkarevi koostatud antoloogia "Aphra"; tõlkejutt: Vance, Jack. Puukoi; algupärane raamat: Hargla, Indrek. French ja Koulu; algupärane jutt: Belials, Veiko. Wereke, wereke, ega sa wesi...

ÕhuLoss - ehtides maailma / Pekka Erelt

Index Scriptorium Estoniae

Erelt, Pekka, 1965-

2011-01-01

Ehtekunstnike rühmitusest õhuLoss (Kadri Mälk, Piret Hirv, Eve Margus-Villems, Tanel Veenre, Kristiina Laurits, Villu Plink, Katrin Sipelgas). Esimest korda astus rühmitus üles 10 aastat tagasi Hollandis Marzee galeriis toimunud näitusel. 2011. aasta augustis-septembris toimus näitus Tallinna Põhjatuletornis

Venemaa ei tahtnud G8-le läinud Eesti ajakirjanikke üle piiri lasta / Krister Paris

Index Scriptorium Estoniae

Paris, Krister, 1977-

2006-01-01

Vene piirivalve hoidis Ivangorodis mitu tundi kinni G-8 tippkohtumisele akrediteeringu saanud kolme Eesti ajakirjanikku. Vt. samas: Venemaa WTO-sse veel ei saa, trump on tuumaenergial; Tanel Mazur. Globaliseerumisvastased saadeti pärast vangistust tagasi Eestisse. Lisad: Meelt jõuti avaldada vaid kaks minutit; Lukashenko vastased kiirelt türmi

Variations in the Spatial Distribution of Gall Bladder Cancer: A Call ...

African Journals Online (AJOL)

adjusted incidence rates (AAR) of certain cancers in specific geographical regions within ... which is second to the highest (Chile) in the world and AAR of carcinoma gall bladder .... Conflict of Interest: None declared. 4. Asmarian NS, Ruzitalab ...

Extracellular Synthesis and Characterization of Gold Nanoparticles Using Mycobacterium sp. BRS2A-AR2 Isolated from the Aerial Roots of the Ghanaian Mangrove Plant, Rhizophora racemosa.

Science.gov (United States)

Camas, Mustafa; Sazak Camas, Anil; Kyeremeh, Kwaku

2018-06-01

Through the use of genomes that have undergone millions of years of evolution, marine Actinobacteria are known to have adapted to rapidly changing environmental pressures. The result is a huge chemical and biological diversity among marine Actinobacteria . It is gradually becoming a known fact that, marine Actinobacteria have the capability to produce nanoparticles which have reasonable sizes and structures with possible applications in biotechnology and pharmacology. Mycobacterium sp. BRS2A-AR2 was isolated from the aerial roots of the mangrove plant Rhizophora racemosa . The Mycobacterium was demonstrated for the first time ever to produce AuNPs with sizes that range between 5 and 55 nm. The highest level absorbance of the biosynthesized AuNPs was typical for actinobacterial strains (2.881 at 545 nm). The polydispersity index was measured as 0.207 in DLS and the zeta potential was negatively charged (- 28.3 mV). Significant vibration stretches were seen at 3314, 2358, 1635 and 667 cm -1 in FT-IR spectra. This demonstrated the possible use of small aliphatic compounds containing -COOH, -OH, -Cl and -NH 2 functional groups in the stabilization of the AuNPs. The effect of the biosynthesized AuNPs on HUVEC and HeLA cell lines was measured at 48 h. IC 50 values were determined at 3500 µg/ml concentration for HUVEC and HeLA cell lines at 45.25 and 53.41% respectively.

Evaluation of the effects of an arm artifact reduction filter in computed tomography

International Nuclear Information System (INIS)

Nozaki, Fumie; Ohno, Hajime; Hirako, Tetsuya

2002-01-01

While performing CT during arterial portography (CTAP) or CT arteriography (CTA), we have instructed patients to in order to reduce streak artifacts. However the repetitive raising and lowering their arms has made it difficult to keep a clean zone and as well as to maintain the position of a target organ. An arm artifact reduction (AAR) filter developed by GE Yokokawa Medical System has been reported to be useful for reducing streak artifacts in CTAP and CTA. The purpose of this study was to estimate the effectiveness of the AAR filter in terms of artifact reduction ratio, CT value, standard deviation and spatial resolution. The use of an AAR filter reduced streak artifacts on images by 15-22% compared with those on images obtained by without the use of the filter and limited deterioration of spatial resolution to within 1%. Moreover, CT value in examination using AAR filter showed no significant change compared with that in non-filter's examination. It is concluded that the use of an AAR filter reduces the burden for the patient and increase the accuracy and flexibility of CT examination while minimizing the reduction in the image quality in CTAP and CTA. (author)

Amino acid repeats avert mRNA folding through conservative substitutions and synonymous codons, regardless of codon bias

Directory of Open Access Journals (Sweden)

Sailen Barik

2017-12-01

Full Text Available A significant number of proteins in all living species contains amino acid repeats (AARs of various lengths and compositions, many of which play important roles in protein structure and function. Here, I have surveyed select homopolymeric single [(An] and double [(ABn] AARs in the human proteome. A close examination of their codon pattern and analysis of RNA structure propensity led to the following set of empirical rules: (1 One class of amino acid repeats (Class I uses a mixture of synonymous codons, some of which approximate the codon bias ratio in the overall human proteome; (2 The second class (Class II disregards the codon bias ratio, and appears to have originated by simple repetition of the same codon (or just a few codons; and finally, (3 In all AARs (including Class I, Class II, and the in-betweens, the codons are chosen in a manner that precludes the formation of RNA secondary structure. It appears that the AAR genes have evolved by orchestrating a balance between codon usage and mRNA secondary structure. The insights gained here should provide a better understanding of AAR evolution and may assist in designing synthetic genes.

Amino acid repeats avert mRNA folding through conservative substitutions and synonymous codons, regardless of codon bias.

Science.gov (United States)

Barik, Sailen

2017-12-01

A significant number of proteins in all living species contains amino acid repeats (AARs) of various lengths and compositions, many of which play important roles in protein structure and function. Here, I have surveyed select homopolymeric single [(A)n] and double [(AB)n] AARs in the human proteome. A close examination of their codon pattern and analysis of RNA structure propensity led to the following set of empirical rules: (1) One class of amino acid repeats (Class I) uses a mixture of synonymous codons, some of which approximate the codon bias ratio in the overall human proteome; (2) The second class (Class II) disregards the codon bias ratio, and appears to have originated by simple repetition of the same codon (or just a few codons); and finally, (3) In all AARs (including Class I, Class II, and the in-betweens), the codons are chosen in a manner that precludes the formation of RNA secondary structure. It appears that the AAR genes have evolved by orchestrating a balance between codon usage and mRNA secondary structure. The insights gained here should provide a better understanding of AAR evolution and may assist in designing synthetic genes.

Structure-Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands

Science.gov (United States)

Hou, Xiyan; Majik, Mahesh S.; Kim, Kyunglim; Pyee, Yuna; Lee, Yoonji; Alexander, Varughese; Chung, Hwa-Jin; Lee, Hyuk Woo; Chandra, Girish; Lee, Jin Hee; Park, Seul-gi; Choi, Won Jun; Kim, Hea Ok; Phan, Khai; Gao, Zhan-Guo; Jacobson, Kenneth A.; Choi, Sun; Lee, Sang Kook; Jeong, Lak Shin

2011-01-01

Truncated N6-substituted-4′-oxo- and 4′-thioadenosine derivatives with C2 or C8 substitution were studied as dual acting A2A and A3 adenosine receptor (AR) ligands. The lithiation-mediated stannyl transfer and palladium-catalyzed cross coupling reactions were utilized for functionalization of the C2 position of 6-chloropurine nucleosides. An unsubstituted 6-amino group and a hydrophobic C2 substituent were required for high affinity at the hA2AAR, but hydrophobic C8 substitution abolished binding at the hA2AAR. However, most of synthesized compounds displayed medium to high binding affinity at the hA3AR, regardless of C2 or C8 substitution, and low efficacy in a functional cAMP assay. Several compounds tended to be full hA2AAR agonists. C2 substitution probed geometrically through hA2AAR-docking, was important for binding in order of hexynyl > hexenyl > hexanyl. Compound 4g was the most potent ligand acting dually as hA2AAR agonist and hA3AR antagonist, which might be useful for treatment of asthma or other inflammatory diseases. PMID:22142423

Myocardial area at risk after ST-elevation myocardial infarction measured with the late gadolinium enhancement after scar remodeling and T2-weighted cardiac magnetic resonance imaging

DEFF Research Database (Denmark)

Lønborg, Jacob; Engstrøm, Thomas; Mathiasen, Anders B

2011-01-01

To evaluate the myocardial area at risk (AAR) measured by the endocardial surface area (ESA) method on late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) when applied after scar remodeling (3 months after index infarction) compared to T2-weighted CMR imaging. One hundred...... and sixty nine patients with ST-elevation myocardial infarction, treated with primary percutaneous coronary intervention, underwent one CMR within 1 week after index treatment to determine the AAR with T2-weighted imaging and a second scan 3 months after to measure AAR with the ESA method...

Myocardial area at risk after ST-elevation myocardial infarction measured with the late gadolinium enhancement after scar remodeling and T2-weighted cardiac magnetic resonance imaging

DEFF Research Database (Denmark)

Lønborg, Jacob; Engstrøm, Thomas; Mathiasen, Anders B

2012-01-01

To evaluate the myocardial area at risk (AAR) measured by the endocardial surface area (ESA) method on late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) when applied after scar remodeling (3 months after index infarction) compared to T2-weighted CMR imaging. One hundred...... and sixty nine patients with ST-elevation myocardial infarction, treated with primary percutaneous coronary intervention, underwent one CMR within 1 week after index treatment to determine the AAR with T2-weighted imaging and a second scan 3 months after to measure AAR with the ESA method...

DVD. Aare Ermel tutvustab : "Rome : The Complete First Season" / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

6 DVD-na on saadaval 12-osaline ajalooline kostüümidraama - seriaal Rooma impeeriumi ajast "Rooma" ("Rome"), mille tootsid aastail 2005-2006 Ameerika tootja Home Box Office (HBO) ja inglaste BBC. Levitab Home Box Office, Inc

78 FR 75573 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Science.gov (United States)

2013-12-12

..., facsimile number (202) 646-3347, or email address [email protected] (HSEEP) After Action Report (AAR) Improvement Plan (IP). Type of Information Collection: Revision of a... Exercise and Evaluation Program (HSEEP) After Action Report (AAR) Improvement Plan (IP). Abstract: The...

GPCR Interaction: 30 [GRIPDB[Archive

Lifescience Database Archive (English)

Full Text Available ernalize upon exposure to the agonist. Oxymetazoline (alpha1aAR selective agonist) induces the cointernali...zation of the alpha1aAR and alpha1bAR, whereas the alpha1bAR does not cointernalize

FIBIT - Fashion is back in Tallinn / Marina Poltavtseva

Index Scriptorium Estoniae

Poltavtseva, Marina

2004-01-01

Moepäevad FIBIT Viru keskuses. Üks idee algatajaid on moekunstnik Katrin Kuldma. 1. oktoobril näidatakse soome moekunstniku Ritva-Liisa Pohjalaineni kollektsiooni Allergia - From Dreams to the Unique. Teisi moedemonstratsioone, millede stilistideks on Riina Põldroos, Aldo Järvsoo, Tanel Veenre ja Katrin Kuldma. Rõivad on valitud Viru keskuse kauplustest

Romantiline mässaja või irooniline intellektuaal? / Kärt Hellerma

Index Scriptorium Estoniae

Hellerma, Kärt, 1956-

2005-01-01

Arvustus: Camus, Albert. Pagendus ja kuningriik : kogutud lühiproosa / prantsuse keelest tõlkinud Triinu Tamm, Krista Vogelberg, Tanel Lepsoo, Henno Rajandi. Tallinn : Varrak, 2004. Ilmunud ka kogumikus: Hellerma, Kärt. Kohanenud kirjandus : valik kirjanduskriitikat 1987-2006. Eesti Keele Sihtasutus : Tallinn, 2006. Lk. 200-202, pealk. Must päike ja igaviku helk

Süütust näpates

Index Scriptorium Estoniae

2007-01-01

Tanel Veenre fotoseeria teatrikostüümidest Draamateatri laval. Stilist: Hanna Tiidus. Naine: Merle Palmiste. Poiss: Joonas (MJ-Models). Jumestus: Margit Soosaar. Juuksed: Jelena Radtsenkova. Kostüümid etendustest "Rohuvoodi" (Aime Unt), "Rehepapp", "Tõeline inspektor koer" (Ene-Liis Semper), "Liilia" (Lilja Blumenfeld), "Mort" (Kersti Varrak), "Potilaadale" (Reet Aus), "Amadeus" (Krista Tool)

Neli uut lühimängufilmi noortelt

Index Scriptorium Estoniae

2004-01-01

Eesti Kino Suvepäevade raames esilinastuvad 3. juunil TPÜ filmi ja video õppetooli mängufilmi režissööride II kursuse kursusetööd-lühimängufilmid : "2.68" (Tanel Toom), "Teispool vihma" (Margus Paju), "Sünnipäev" (Kaupo Kruusiauk) ja "Liivakellade parandaja" (Anu Aun)

Uljas ja uudishimulik 20-aastane / Madli Pesti

Index Scriptorium Estoniae

Pesti, Madli, 1980-

2007-01-01

VAT Teatri lavastustest - Amélie Nothombi romaani järgi "Vaenlase kosmeetika" (lav. Peeter Raudsepp), Kristof Magnussoni "Meeste varjupaik" (lav. Christian Römer), Hans Christian Anderseni järgi "Merineitsi" (lav. Aare Toikka) ja Urmas Vadi "Elvis oli kapis" (lav. Aare Toikka)

Acute antibody-mediated rejection of skin grafts without involvement of granulocytes or complement

International Nuclear Information System (INIS)

Bogman, M.J.; Cornelissen, I.M.; Koene, R.A.

1984-01-01

In immunosuppressed mice that carry rat skin xeno-grafts, acute antibody-mediated graft rejection (AAR) can be induced by intravenous administration of mouse anti-rat globulin. Dependent on the amount of antibody injected and on the complement status of the recipient, an Arthus-like or a Shwartzman-like pattern of vasculitis occurs. The role of polymorphonuclear granulocytes (PMNs) in either type of vasculitis was tested by inducing AAR in recipients depleted of PMNs by total body irradiation. Despite the absence of PMNs in the graft vessels, AAR occurred both in the Arthus-like and in the Shwartzman-like type. Moreover, AAR could be elicited in PMN-depleted recipients that were complement-depleted by cobra venom factor treatment or were congenitally C5-deficient. We conclude that neither the PMN nor complement is an essential mediator the PMN nor complement is an essential mediator in this form of antibody-mediated vasculitis

Turunduskunsti tippteos / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2008-01-01

Kokkupandavast nüüdiskunsti galeriist Mobile Art, mis alates 2008.a. veebruarist on rännanud Hongkongist Tokyosse ja oktoobris jõuab New Yorki. Idee autor Coco Chaneli moemaja juht ja disainer Karl Lagerfeld, arhitekt Zaha Hadid. Näitusel eksponeeritud tööde teemaks on Chaneli käekott

Olemise arheoloog / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Pariisis elavast ja töötavast eesti kunstnikust Kaia Kiigest, kes jõudis filosoofiaõpingute kaudu maalimise juurde, tema maalinäitusest "Strata" Tallinnas galeriis Vaal 2.-21. aprillini. Kaia Kiik loomisprotsessist, sõnumist, keskkonnast, mälust, Eestist ja Pariisist

GPCR Interaction: 35 [GRIPDB[Archive

Lifescience Database Archive (English)

Full Text Available and alpha2aAR form robust hetero dimer in HEK-293 cells. An interaction between beta1AR and alpha2aAR is reg...ulated by glycosylation. The interaction may play a key role in cross-talk and mu

Euro on teel / Ivar Jung

Index Scriptorium Estoniae

Jung, Ivar

2005-01-01

Reet Varblase kureeritud näitus "Oma raha" Tallinna Kunstihoone galeriis 12. XI-4. XII. Gints Gabransi videotest, Jaan Jaanisoo masin-installatsioonist, Siim-Tanel Annuse tööst. 2. XII galeriis toimunud kunstnike, kultuurihuviliste ja rahamaailma esindajate (Eesti Panga asepresident Rein Minka, endine president Vahur Kraft, rahandusministri nõuniku kt Veiko Valkiainen) kohtumisest

Innovaatiliste äriideede konkursi võitjad / Varje Sootak

Index Scriptorium Estoniae

Sootak, Varje, 1946-

2006-01-01

Ettevõtjatele, teadlastele ja üliõpilastele korraldatud NETS (New Entrepreneurs in Technology and Science) ettevõtlusprogrammi innovaatiliste äriideede konkursil selgusid 15 parimat, kellest mitmed on Tartu Ülikooli üliõpilased ja töötajad: Anton Litvinenko, Fred Valk, Madis Kauts, Mario Plaas, Marko Daljajev, Meelis Kaldalu, Reigo Ginter, Tanel Tarkmees

Suur müüdikonverents Tartus / Evelin Banhard

Index Scriptorium Estoniae

Banhard, Evelin

2008-01-01

Tartus toimunud rahvusvahelisest konverentsist "Suurte kultuuriliste ja kirjanduslike müütide saatus tänapäeval". Pikemalt Liisa Saariluoma, Jüri Talveti, Angelika Stefanova, Tanel Lepsoo, Caroline De Wagteri, Sonia Bravo Utrera, Ana Martinoska, Marin Laagi, Rutt Hinrikuse, Jeanne Elisabeth Gleseneri, Sabine Coelsch-Foisneri, Harvey L. Hixi ja Hannu K. Riikoneni ettekannetest

Eesti kunst Berliinis

Index Scriptorium Estoniae

2003-01-01

29. novembrist Berliini Giedre Bartelti galeriis fotonäitus "(un)dressed Body in the Baltic Photo. Art vol 2: Estonia". Näituse teema: keha ja selle kujutamisviisid, seksuaalsus ja aseksuaalsus. Eksponeeritud Margot Kase, Peeter Lauritsa, Ly Lestbergi, Mark Raidpere, Ene-Liis Semperi, Liina Siibi, Mare Tralla ja Tanel Veenre video- ja fotolooming. Kuraator Sirje Helme

Plaadid / Priit Hõbemägi

Index Scriptorium Estoniae

Hõbemägi, Priit, 1957-

2006-01-01

Uutest heliplaatidest "Wolfmother", Futureheads "News and Tributes", Sonic Youth "Rather Ripped", tanel Padar & The Sun "100% rock'n'roll", The Raconteurs "Broken toy Soldiers", neil Young "Living With War", Moloko "Catalogue", Nelly Furtado "Loose", Busta Rhymes "Big Bang", "R2 Live. Vol 1", Tiesto "In Search Of Sunrise", "Moon Taxi", Zero 7 "The Garden"

Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group

Directory of Open Access Journals (Sweden)

Lisa Pleyer

2017-02-01

Full Text Available We recently published a clinically-meaningful improvement in median overall survival (OS for patients with acute myeloid leukaemia (AML, >30% bone marrow (BM blasts and white blood cell (WBC count ≤15 G/L, treated with front-line azacitidine versus conventional care regimens within a phase 3 clinical trial (AZA-AML-001; NCT01074047; registered: February 2010. As results obtained in clinical trials are facing increased pressure to be confirmed by real-world data, we aimed to test whether data obtained in the AZA-AML-001 trial accurately represent observations made in routine clinical practice by analysing additional AML patients treated with azacitidine front-line within the Austrian Azacitidine Registry (AAR; NCT01595295; registered: May 2012 and directly comparing patient-level data of both cohorts. We assessed the efficacy of front-line azacitidine in a total of 407 patients with newly-diagnosed AML. Firstly, we compared data from AML patients with WBC ≤ 15 G/L and >30% BM blasts included within the AZA-AML-001 trial treated with azacitidine (“AML-001” cohort; n = 214 with AAR patients meeting the same inclusion criteria (“AAR (001-like” cohort; n = 95. The current analysis thus represents a new sub-analysis of the AML-001 trial, which is directly compared with a new sub-analysis of the AAR. Baseline characteristics, azacitidine application, response rates and OS were comparable between all patient cohorts within the trial or registry setting. Median OS was 9.9 versus 10.8 months (p = 0.616 for “AML-001” versus “AAR (001-like” cohorts, respectively. Secondly, we pooled data from both cohorts (n = 309 and assessed the outcome. Median OS of the pooled cohorts was 10.3 (95% confidence interval: 8.7, 12.6 months, and the one-year survival rate was 45.8%. Thirdly, we compared data from AAR patients meeting AZA-AML-001 trial inclusion criteria (n = 95 versus all AAR patients with World Health Organization (WHO-defined AML (“AAR

49 CFR 1135.1 - Quarterly adjustment.

Science.gov (United States)

2010-10-01

... subsequent amendments thereto. In addition, the AAR shall calculate the productivity-adjusted RCAF as..., the Association of American Railroads (AAR) shall calculate and file with the Board by the fifth day... all-inclusive index of railroad costs and calculate and file the RCAF unadjusted for changes in...

Using Rapid Improvement Events for Disaster After-Action Reviews: Experience in a Hospital Information Technology Outage and Response.

Science.gov (United States)

Little, Charles M; McStay, Christopher; Oeth, Justin; Koehler, April; Bookman, Kelly

2018-02-01

The use of after-action reviews (AARs) following major emergency events, such as a disaster, is common and mandated for hospitals and similar organizations. There is a recurrent challenge of identified problems not being resolved and repeated in subsequent events. A process improvement technique called a rapid improvement event (RIE) was used to conduct an AAR following a complete information technology (IT) outage at a large urban hospital. Using RIE methodology to conduct the AAR allowed for the rapid development and implementation of major process improvements to prepare for future IT downtime events. Thus, process improvement methodology, particularly the RIE, is suited for conducting AARs following disasters and holds promise for improving outcomes in emergency management. Little CM , McStay C , Oeth J , Koehler A , Bookman K . Using rapid improvement events for disaster after-action reviews: experience in a hospital information technology outage and response. Prehosp Disaster Med. 2018;33(1):98-100.

Aneurisma da Artéria Renal: cirurgia renal ex-vivo - a propósito de um caso clínico Renal Artery Aneurysm: ex-vivo repair - a case report

Directory of Open Access Journals (Sweden)

Clara Nogueira

2012-09-01

Full Text Available Os aneurismas da artéria renal (AAR são raros, frequentemente assintomáticos, de etiologia variada, frequentemente secundários a aterosclerose e anomalias congénitas. Os AAR com diâmetro superior a 2 cm têm indicação cirúrgica. A escolha da técnica cirúrgica depende da localização anatómica e complexidade do AAR, bem como do tempo previsível de isquemia renal. Os autores descrevem um caso de auto-transplante renal, para tratamento de dois AAR complexos.Renal artery aneurysms (RAA are rare, frequently asymptomatic, with variable etiology, frequently due to atherosclerosis and congenital anomalies. Surgical treatment is indicated for RAA with a diameter greater to 2 cm. Surgical technique will depend on RAA anatomic localization and complexity, as well as, predicted renal isquemic time. The authors report an auto-transplant for treatment of two complex RAA.

Clinical value of spleen acoustic radiation force impulse, aspartate aminotransferase-to-platelet ratio index, and aspartate aminotransferase/alanine aminotransferase ratio in predicting esophageal varices in patients with liver cirrhosis

Directory of Open Access Journals (Sweden)

ZHANG Dakun

2018-03-01

Full Text Available ObjectiveTo investigate the spleen stiffness of patients with chronic hepatitis and liver cirrhosis by spleen acoustic radiation force impulse (ARFI, aspartate aminotransferase-to-platelet ratio index (APRI, and aspartate aminotransferase/alanine aminotransferase ratio (AAR, as well as the clinical value of these three noninvasive techniques in predicting esophageal varices (EV in patients with liver cirrhosis. MethodsA total of 247 patients with chronic hepatitis and liver cirrhosis were enrolled, and ARFI was used to measure real-time spleen stiffness. APRI and AAR were calculated. Gastroscopy was performed within one week before and after measurement to clarify the degree of EV. With the results of gastroscopy as the gold standard, the receiver operating characteristic (ROC curve was used to compare the clinical value of spleen ARFI value, APRI, and AAR in the diagnosis of EV in patients with liver cirrhosis. The t-test was used for comparison of continuous data between two groups. ResultsThere were significant differences between the EV group (n=169 and the non-EV group (n=78 in spleen ARFI stiffness (3.64±0.53 m/s vs 2.97±0.65 m/s, t=-7.93, P＜0.001, APRI (0.87±091 vs 0.52±0.80, t=-2.90, P=0.004, and AAR (1.54±0.67 vs 1.29±0.55, t=-2.93, P=0.004. Spleen ARFI, APRI, and AAR had an area under the ROC curve of 0.80, 0.72, and 0.63, respectively, in predicting EV in patients with liver cirrhosis, there was a significant difference between spleen ARFI stiffness and AAR (P=0.005, while there was no significant difference between spleen ARFI stiffness and APRI (P=0.10. ConclusionARFI is a real-time ultrasound elastography technique, and compared with APRI and AAR, spleen stiffness measured by ARFI can predict EV in patients with chronic hepatitis and liver cirrhosis more accurately and noninvasively and thus holds promise for clinical application.

Eestlane ja sakslane Kunstihoones

Index Scriptorium Estoniae

1998-01-01

Siim-Tanel Annuse ja Abraham David Christiani ühisnäitus 18. dets.-st Tallinna Kunstihoones. Kuraator Dorothee Bauerle-Willert. A. D. Christianilt on näitusel skulptuurid, Mississippi joonistuste seeria, S.-T. Annuselt maalid. Näituse avamisele järgnenud Krista Kodrese juhendatud diskussioonil "Siin ئ piirideta, läbisegi ja piirideta või hoopis maailmakunst provintsist" osalejad

Pop & rock. Retro. Klassika / Margus Kiis

Index Scriptorium Estoniae

Kiis, Margus

2001-01-01

Orbital "The Altogether", Vonda Shepard "Ally McBeal (For Once In My Life)", Jääboiler "Niiongi", Tanel Padar ja Speed Free "Woman Knows", Arvo Pärt "Johannes-Passion", Nikka Costa "Everybody Got Their Something", Stevie Nicks "Trouble In Shangri-La", Richard Thompson "Action Packed The Best of the Capitol Years", "Eurovision Song Contest 2001" heliplaatide tutvustused

Танель Тоом прошел по красной дорожке / интервьюировал Тийт Туумалу

Index Scriptorium Estoniae

Тоом, Танел, 1982-

2011-01-01

Eesti režissööri Tanel Toomi lühifilm "Pihtimus" ("The Confession") kandideeris parima lühifilmi kategoorias Oscarile. (Võitis Luke Matheny "God of Love", USA 2010). Noor režissöör räägib oma muljeid Oscarite jagamise tseremooniast. Ära on toodud ka lühike võitjate nimekiri

Muusika / DJ Pickney Tiger

Index Scriptorium Estoniae

DJ Pickney Tiger, pseud., 1970-

2008-01-01

Kontsertidest: rootsi rockansamblid Backyard Babies ja Bullet 10. dets. Tallinnas klubis Tapper, Tanel Padari ja The Sun heliplaadi "Here Comes The Sun" esitluskontsedid, Alina Rostovskaya & Jazzmobile 4. dets. Tallinnas Lindakivi kultuurikeskuses ja 5. dets. NO99 Jazziklubis, Dessert Time ja Gine Anderssen 8. dets. Viljandi Pärimusmuusika Aidas, inglise punkansambel Sham 69 4. dets. Pärnus Mai keskuse Rockiklubis

Bedwetters jõudis auhinnagalale

Index Scriptorium Estoniae

2007-01-01

MTV Euroopa uute helide auhinna kategoorias pääses edasi Noortebänd 2007 võitja Bedwetters, parima Balti artisti kategoorias Tanel Padar & The Sun, Double Faced Eels ja Tribes of the City Lätist ning Jurga ja Skamp Leedust. Galakontset toimub 1. nov. Münchenis, oma lemmikute poolt saab hääletada veebilehel www.mtvema.com

München ei ole ainult Oktoberfest / Albert Trapeezh

Index Scriptorium Estoniae

Trapeež, Albert, pseud., 1947-

2005-01-01

Eesti nüüdiskunsti näitusest Müncheni kunstikeskuses Aktionsforum. Osalesid Siim-Tanel Annus, Jaan Elken, Jüri Kass, Ülle Marks, Eve Kask, Lennart Mänd, Tiiu Kirsipuu, Leonhard Lapin, Raul Meel, Liina Siib, Andres Tolts ja Urmas Viik. Näituse kataloogi eestipoolsed tekstid kirjutas Harry Liivrand. Müncheni moodsaimast kunstikeskusest Pinakothek der Moderne'ist

Kaunase kunstnike külaskäik Tartusse / Kübarsepp, Triin [?Riin

Index Scriptorium Estoniae

Kübarsepp, Triin [?Riin

2006-01-01

Tartus saab näha 21 eri põlvkondadesse kuuluva ja erinevaid stiile viljeleva Kaunase kunstniku loomingut. Näituse kuraatorid kunstiteadlased Kristina Budryte ja Armidas Zhalyps. Leitud ühisjooni eesti ja leedu kunstnike loomingus. Antanas Obcarkas - Siim-Tanel Annus, Alfonsas Vilpishauskas - Vano Allsalu, Agne Jonkute - Tõnis Saadoja. Näitusi aitas korraldada kunstikollektsionäär Matti Milius

Kui sind ei ole siin, siis...

Index Scriptorium Estoniae

Käesel, Tiina, 1943-

2010-01-01

Münchenis 62. rahvusvahelise käsitöömessi raames toimunud rahvusvahelisest konkurssnäitusest "Ehe" (Schmuck"), kuhu Eestist oli valitud Tanel Veenre tööga "Flora talv", konkurssnäitusest "Talendid" ("Talente"), Eesti ehtekunstnike rühmituse ÕhuLoss näitusest Müncheni Vana põhjakalmistu surnuaiavahi majas jt. ehtenäitustest

Noor filmipõlvkond tulekul

Index Scriptorium Estoniae

2004-01-01

Eesti Kino Suvepäevade raames esilinastusid 3. juunil TPÜ filmi ja video õppetooli mängufilmi režissööride II kursuse kursusetööd-lühimängufilmid : "2.68" (Tanel Toom), "Teispool vihma" (Margus Paju), "Sünnipäev" (Kaupo Kruusiauk) ja "Liivakellade parandaja" (Anu Aun). Kursuse juhendaja on Jüri Sillart

Noored režissöörid esitlevad uusi filme / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Eesti Kino Suvepäevade raames esilinastuvad 3. juunil TPÜ filmi ja video õppetooli mängufilmi režissööride II kursuse kursusetööd-lühimängufilmid : "2.68" (Tanel Toom), "Teispool vihma" (Margus Paju), "Sünnipäev" (Kaupo Kruusiauk) ja "Liivakellade parandaja" (Anu Aun). Kursuse juhendaja on Jüri Sillart

DVD. Aare Ermel soovitab "Meie isade lipud", "Kirjad Iwo Jimalt" / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Clint Eastwoodi kaks filmi on Teises Maailmasõjas USA-Jaapani Iwo Jima saarel peetud lahingu teemal. USA poolt vaadatuna - "Meie isade lipud" ("Flags of Our Fathers"), Jaapani poolt - "Kirjad Iwo Jimalt" ("Letters From Iwo Jima") : Ameerika Ühendriigid 2006

An analysis of root cause identification and continuous quality improvement in public health H1N1 after-action reports.

Science.gov (United States)

Singleton, Christa-Marie; Debastiani, Summer; Rose, Dale; Kahn, Emily B

2014-01-01

To identify the extent to which the Homeland Security Exercise and Evaluation Program's (HSEEP) After Action Report/Improvement Plan (AAR/IP) template was followed by public health entities and facilitated the identification of detailed corrective actions and continuous improvement. Data were drawn from the US H1N1 Public Health Emergency Response (PHER) federal grant awardees (n = 62). After action report/improvement plan text was examined to identify the presence of AAR/IP HSEEP elements and characterized as "minimally complete," "partially complete," or "complete." Corrective actions (CA) and recommendations within the IP focusing on performance deficits were coded as specific, measurable, and time-bound, and whether they were associated with a problem that met root cause criteria and whether the CA/recommendation was intended to address or fix the root cause. A total of 2619 CA/recommendations were identified. More than half (n = 1480, 57%) addressed root causes. Corrective actions/recommendations associated with complete AARs more frequently addressed root cause (58% vs 51%, χ = 9.1, P < 0.003) and were more specific (34% vs 23%, χ = 32.3, P < 0.0001), measurable (30% vs 18%, χ = 37.9, P < 0.0001), and time-bound (38% vs 15%, χ = 115.5, P < 0.0001) than partially complete AARs. The same pattern was not observed with completeness of IPs. Corrective actions and recommendations were similarly specific and measurable. Recommendations significantly addressed root cause more than CAs. Our analysis indicates a possible lack of awardee distinction between CA and recommendations in AARs. As HSEEP adapts to align with the 2011 National Preparedness Goal and National Preparedness System, future HSEEP documents should emphasize the importance of root cause analysis as a required element within AAR documents and templates in the exercise and real incident environment, as well as the need for specific and measurable CAs.

Parimaid õpetajaid näeb taas terve Eesti / Sirje Pärismaa

Index Scriptorium Estoniae

Pärismaa, Sirje, 1958-

2014-01-01

Üleriigilise üldhariduse tunnustussüsteemi „Eestimaa õpib ja tänab“ tänuüritusest, kus pälvisid auhinna aasta klassijuhataja Aare Veedla, Luua Metsanduskooli õpetaja Aino Mölder, Hugo Treffneri Gümnaasiumi õpetaja Aare Ristikivi, aasta lasteaiaõpetaja Julia Faizullova ning aasta teo tiitli pälvis Konguta kool

Ammende pakub suvemuusikat / Silja Joon

Index Scriptorium Estoniae

Joon, Silja, 1966-

2007-01-01

Kontsertidest Pärnus Ammende villas: 5. juulil "Mõeldes Sinule" (Laura Põldvere, Jorma Toots, Marti Tärn, Ahto Abner), 12. juulil Kadri Voorand, Jürmo Eespere, Mihkel Mälgand ja Tanel Ruben, 19. juulil Tõnu Naissoo, Raul Vaigla ja Marko Naissoo kontserdiga "Tõnu Naissoo Eclectic Electric Trio", 26. juulil Holger Marjamaa kvartett (Holger Marjamaa, Mairo Marjamaa, Peedu Kass ja Dmitri Nikolajevski)

Sillarti "lapsed" said käe valgeks / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

2004-01-01

Eesti Kino Suvepäevade raames esilinastusid 3. juunil TPÜ filmi ja video õppetooli mängufilmi režissööride II kursuse (juhendaja Jüri Sillart) kursusetööd-lühimängufilmid : "2.68" (Tanel Toom), "Teispool vihma" (Margus Paju), "Sünnipäev" (Kaupo Kruusiauk) ja telerežii lõpetanud Anu Auna "Liivakellade parandaja"

Linaristsed täiskuu aegu / Grete Nootre

Index Scriptorium Estoniae

Nootre, Grete

2004-01-01

Eesti Kino Suvepäevade raames esilinastuvad 3. juunil TPÜ filmi ja video õppetooli mängufilmi režissööride II kursuse (juhendaja Jüri Sillart) kursusetööd-lühimängufilmid : "2.68" (Tanel Toom), "Teispool vihma" (Margus Paju), "Sünnipäev" (Kaupo Kruusiauk) ja telerežii lõpetanud Anu Auna "Liivakellade parandaja"

Kolm meest paadis (naisest rääkimata) / Karol Ansip

Index Scriptorium Estoniae

Ansip, Karol

2004-01-01

Eesti Kino Suvepäevade raames esilinastusid 3. juunil TPÜ filmi ja video õppetooli mängufilmi režissööride II kursuse (juhendaja Jüri Sillart) kursusetööd-lühimängufilmid : "2.68" (Tanel Toom), "Teispool vihma" (Margus Paju), "Sünnipäev" (Kaupo Kruusiauk) ja telerežii lõpetanud Anu Auna "Liivakellade parandaja"

Muusika / Priit Kuusk

Index Scriptorium Estoniae

Kuusk, Priit, 1938-

2004-01-01

Mihkel Pollpälvis XVIII Rina Sala Gallo rahvusvahelisel pianistide konkursil esikoha. Igal reedel hakkavad toimuma Vanalinnastuudio väikeses saalis jazziklubi-kontserdid. Vanemuise teatri menumuusikalis "Viiuldaja katusel" astusid esmakordselt vaatajate ette uued osatäitjad. Ardo-Ran Varres ja Tanel Jonas. Pärdil uus teos "Da pacem domine". 28.- 31. X toimuvad Nõmme muusikakoolis üleriigilised klaveriõpetajate päevad

Uso de la distribución normal para cuantificar la calidad del riego en sistemas de aspersión estacionario

Directory of Open Access Journals (Sweden)

José Nicolás Ortiz Romero

2017-12-01

Full Text Available En el campo experimental de riego del Decanato de Agronomía de la UCLA se llevó a cabo un estudio cuyo objetivo fue cuantificar el reparto del agua y los parámetros de calidad del riego en un sistema de aspersión estacionario durante dos ciclos del cultivo de caraota usando la distribución normal. Se determinó el área adecuadamente regada (AAR en 13 eventos de riego, y esta se relacionó con los parámetros eficiencia de aplicación (Efa, pérdidas por percolación, eficiencia de almacenamiento (Efal y el déficit. Los resultados mostraron que la Efal y la percolación aumentaron con el incremento del AAR; mientras, la Efa y el déficit disminuyeron con el aumento del AAR. Los parámetros de calidad del riego en función del AAR se ajustaron apropiadamente a una regresión lineal, donde los coeficientes y el modelo resultaron significativos (p

Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode Classification

Directory of Open Access Journals (Sweden)

Pengfei Fang

2015-12-01

Full Text Available Aminoacyl-tRNA synthetases (aaRSs are enzymes that catalyze the transfer of amino acids to their cognate tRNAs as building blocks for translation. Each of the aaRS families plays a pivotal role in protein biosynthesis and is indispensable for cell growth and survival. In addition, aaRSs in higher species have evolved important non-translational functions. These translational and non-translational functions of aaRS are attractive for developing antibacterial, antifungal, and antiparasitic agents and for treating other human diseases. The interplay between amino acids, tRNA, ATP, EF-Tu and non-canonical binding partners, had shaped each family with distinct pattern of key sites for regulation, with characters varying among species across the path of evolution. These sporadic variations in the aaRSs offer great opportunity to target these essential enzymes for therapy. Up to this day, growing numbers of aaRS inhibitors have been discovered and developed. Here, we summarize the latest developments and structural studies of aaRS inhibitors, and classify them with distinct binding modes into five categories.

Aminoacyl-tRNA synthetases database Y2K.

Science.gov (United States)

Szymanski, M; Barciszewski, J

2000-01-01

The aminoacyl-tRNA synthetases (AARS) are a diverse group of enzymes that ensure the fidelity of transfer of genetic information from DNA into protein. They catalyse the attachment of amino acids to transfer RNAs and thereby establish the rules of the genetic code by virtue of matching the nucleotide triplet of the anticodon with its cognate amino acid. Currently, 818 AARS primary structures have been reported from archaebacteria, eubacteria, mitochondria, chloro-plasts and eukaryotic cells. The database is a compilation of the amino acid sequences of all AARSs, known to date, which are available as separate entries or alignments of related proteins via the WWW at http://rose.man.poznan.pl/aars/index.html

75 FR 59108 - Positive Train Control Systems

Science.gov (United States)

2010-09-27

..., place the two agencies in conflict. According to AAR, ``[i]f under the PHMSA analysis of two routes one... requirement conflicts with RSIA08. AAR states that: [i]f FRA decides that TIH should be routed on a line... an inevitable impact on some routing decisions. One of the 27 factors called out for analysis under...

76 FR 52918 - Positive Train Control Systems

Science.gov (United States)

2011-08-24

... Railroads (AAR) filed suit in the U.S. Court of Appeals for the District of Columbia Circuit challenging the..., 2010, the AAR filed a petition for review of the rule with the U.S. Court of Appeals for the District... rational bases. IV. Regulatory Impact and Notices A. Executive Orders 12866 and 13563 and DOT Regulatory...

Interesting coin finds of 2006 / Mauri Kiudsoo

Index Scriptorium Estoniae

Kiudsoo, Mauri, 1973-

2007-01-01

2006. aasta huvitavamatest mündileidudest. Lisaks arheoloogilistelt kaevamistelt saadud vermingutele omandati 2006. aastal kolm mündiaaret : Alansi aare Harjumaalt, ligi poolsada araabia hõbemünti sisaldav aare Tartust ning tänu politsei kaasabile jõudsid Eestisse tagasi Ubina hõbeaadre kaevamistelt varastatud hõbemündid. Eestist leitud rooma müntidest

Madame Bovary / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

Austraalias oma filmikarjääri alustanud näitlejanna Frances O'Connor (1969), kes mängib nimiosa Inglismaa-USA seriaalis Gustave Flaubert'i romaani "Madame Bovary" ainetel. Ka : Nädal nr. 52, lk. 17

Tavaline roomlane / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Iiri päritolu näitleja Ray Richardson, kes kehastab ajaloolises teleseriaalis "Rooma" (tootjad Ameerika HBO, inglaste BBC ja itaallaste RAI) Gaius Julius Caesari sõdurit Titus Pullot. Sama : Teleleht nr. 1, lk. 14 : ill

Fosforiidisõda / Juhan Aare

Index Scriptorium Estoniae

Aare, Juhan, 1948-

1999-01-01

Järg Jan/5;6;7;8;9;11;12;13;14;15;16;18;19;20;21;22;23;25;26;27;28;29;30/Feb/1;2;3;4;5;6;8;9;10;11;12;13;15;16;17;18;19;20;22;23;25;26;27/Mar/1;2;3;4;5;6;8;9;10;11;12;13;15;16;17;18;20;22;23;24;25;26;27;29;30;31/Apr/1;2;35;6;7;8;9;10;12;13;14;15;16;17;19;20;21;22;23;24;26;27;28;29;30/May/3;4;5;6;7;8;10;11;12;13;14;15;17;18;19;20;21;22;24;25;26;27;28;29;31

Current Practice and Theoretical Foundations of the After Action Review

Science.gov (United States)

2011-06-01

Stephen L. Goldberg , Chief U.S. Army Research Institute for the Behavioral and Social Sciences 2511 Jefferson Davis Highway, Arlington, Virginia...were many occasions where 37 the facilitators’ knowledge of the battle tempo , dynamics, and resources added to the SA of team members. Such...attending AARs. There appear to be frequent variations in organizational status among participants in traditional industry AARs. In military

Puhu ristist maailma teedele / Helmut Piirimäe

Index Scriptorium Estoniae

Piirimäe, Helmut, 1930-

2009-01-01

Tutvustus: Varje dag...-sextio år av lycka. Till minnet av Aare R. Mörner (1926-2008). Utgivare: Magnus och Henrik Mörner. Printed in Hungary, 2008. /Tõlge/: Iga päev...- kuuskümmend aastat õnne. Aare-R. Mörneri (1926-2008) mälestuseks. Väljaandjad: Magnus ja Henrik Mörner. Trükitud Ungaris, 2008. 199 lk.

The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment.

Science.gov (United States)

Saint-Léger, Adélaïde; Sinadinos, Christopher; Ribas de Pouplana, Lluís

2016-04-02

Malaria remains a major global health problem. Parasite resistance to existing drugs makes development of new antimalarials an urgency. The protein synthesis machinery is an excellent target for the development of new anti-infectives, and aminoacyl-tRNA synthetases (aaRS) have been validated as antimalarial drug targets. However, avoiding the emergence of drug resistance and improving selectivity to target aaRS in apicomplexan parasites, such as Plasmodium falciparum, remain crucial challenges. Here we discuss such issues using examples of known inhibitors of P. falciparum aaRS, namely halofuginone, cladosporin and borrelidin (inhibitors of ProRS, LysRS and ThrRS, respectively). Encouraging recent results provide useful guidelines to facilitate the development of novel drug candidates which are more potent and selective against these essential enzymes.

The Sun murrab Baltimaadesse ja Soome

Index Scriptorium Estoniae

2008-01-01

Aprillis andis ansambel Tanel Padar & The Sun Soomes, Lätis, Leedus ja Eestis üksteist kontserti. Heliplaadi "Here Gomes The Sun" lugu "Hopelessness You" on Soome raadiote tipp 300s neljakümnendal kohal, lugu "Learn the game" on Leedu FM99 raadios 33 enim mängitava loo seas, laul "One of those days" saavutas Läti raadio SWH rokkmuusika edetabelis teise koha.

Kunstinäituselt Jumala ja kanade juurde ning sealt põrgusse / Riin Kübarsepp

Index Scriptorium Estoniae

Kübarsepp, Riin, 1978-

2005-01-01

Mirja-Mari Smidti ja Allan Tõnissoo näitus "Kunstinäitus" Hobusepea galeriis 31. III-18. IV. Tanel Saare "Gott und Huhn episode IV: seed shower" kuni 23. IV Draakoni galeriis. Kuni 24. IV Tallinna Linnagaleriis Pirjetta Branderi näitus "Põrgu ja teised jutud", millega oli kaasas Mikko Tuhkaneni kunstniku loomingu analüüsi sisaldav kirjutis "A Woman's work is never done"

Kui sõnadest enam ei piisa, siis - muusika / Kadri Mälk

Index Scriptorium Estoniae

Mälk, Kadri, 1958-

2008-01-01

Rahvusvahelisest ehtekunstisündmusest "Schmuckszene" (peakorraldaja Wolfgang Lösche) Münchenis, peanäitusest (kuraator Ralph Turner) Müncheni messikeskuses, satelliitnäitustest. Eestist pääses peanäitusele Maarja Niinemägi, peapreemia sai Jantje Fleischhut. Kaasaegse ehtekunsti toetajate ühenduse (Die Fördergesellschaft Neuer Schmuck) aastapreemia sai Peter Chang. Võrdluseks Tanel Veenre näitusest "Kui sõnadest ei piisa" Hop-galeriis

The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.

Science.gov (United States)

Schramm, N L; McDonald, M P; Limbird, L E

2001-07-01

The noradrenergic system is involved in the regulation of many physiological and psychological processes, including the modulation of mood. The alpha(2)-adrenergic receptors (alpha(2)-ARs) modulate norepinephrine release, as well as the release of serotonin and other neurotransmitters, and are therefore potential targets for antidepressant and anxiolytic drug development. The current studies were undertaken to examine the role of the alpha(2A) subtype of alpha(2)-AR in mouse behavioral models of depression and anxiety. We have observed that the genetic knock-out of the alpha(2A)-AR makes mice less active in a modified version of Porsolt's forced swim test and insensitive to the antidepressant effects of the tricyclic drug imipramine in this paradigm. Furthermore, alpha(2A)-AR knock-out mice appear more anxious than wild-type C57 Bl/6 mice in the rearing and light-dark models of anxiety after injection stress. These findings suggest that the alpha(2A)-AR may play a protective role in some forms of depression and anxiety and that the antidepressant effects of imipramine may be mediated by the alpha(2A)-AR.

Totaalne disainiring Tallinnas / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Rotermanni kvartali elevaatoris näitus "Disaini elevaator", Prooviveskis võistluse "Eesti disain ja elukeskkond 2009" nominentide tööde väljapanek ja rahvusvaheline näitus "BIO esitleb: BIO disainiparemik" (töid Sloveenia tööstusdisaini biennaalilt), jahulao aatriumis näitus "Polish Design. The Essence" 11. okt.-ni. A-Galeriis Maria Valdma näitus "Tolm" 12. okt.-ni. Galeriis Hop tekstiilikunstnik Lylian Meistri ja Katarina Meistri näitus "Erailu" 6. okt.-ni. Galeriis Galerii Kaks tekstiilikunstnik Liivi Leppiku ruumiliste tekstiilipannoode näitus 14. okt.-ni. Eesti Kunstiakadeemia galeriis Eesti Kunstiakadeemia tekstiilikunsti eriala üliõpilaste näitus "Glamuurselt kodutu" 6. okt.-ni

Disain parandab maailma / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Taani disainiauhinna INDEX: Award 2011eelžüriile laekus ligi tuhat võistlustööd, millest valiti finaali 61 tööd. Tooted on jaotatud viide kategooriasse - keha, kodu, töö, mäng ja kogukond. Ettevõtmise moto - "Design to Improve Life" ("Disain elu edendamiseks")

Disain parandab maailma / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Rändnäitus "INDEX : Award Exhibition 2007: winners of tour" Tallinnas Harju tänava haljasalal 19. juulini. Võistlusel INDEX : Award osalevatelt toodetelt oodatakse peale hea väljanägemise, et nad muudaksid elu paremaks

Tagasi puu otsa! / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Puu otsa ehitatud ja puudel rippuvatest majadest. Üle 60 San Francisco kunstniku koostöös sündinud Steampunk Tree House, Takashi Kobayashi loodud puumaja, Toronto arhitektuuri- ja disainiülikooli tudengi Lukasz Kosi disainitud 4TreeHouse, Tom Chudleighi disainitus "Vaba hinge sfäärid", 02 Sustainability Tree House, Romero Studiosi ja Baumraumi puumajad

Noored ja oreoolid / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Köler Prize'i nominentide näitus Eesti Kaasaegse Kunsti Muuseumis 12. juunini 2011. Köler Prize'i sai skulptor ja installatsioonikunstnik Jevgeni Zolotko, publikupreemia maalikunstnik Tõnis Saadoja. Eesti Kunstiakadeemia noore kunstniku preemia pälvis vabade kunstide teaduskonna bakalaureusetaseme lõpetajatest skulptor Ulla Juske, magistritaseme lõpetajatest maalikunstnik Kristi Kongi ja vabakunstnik Eva Labotkin. Premeeritute loomingust

Taastuvenergia kasutamine Rõuges / Tanel Lukason

Index Scriptorium Estoniae

Lukason, Tanel

2005-01-01

Rõuge piirkond on hea näide, kuidas oskusliku tegutsemisega on võimalik saavutada märkimisväärset positiivset efekti biomassi, veejõu, maasse akumuleeritud soojuse ja otsese päikesekiirguse kasutamisel elektri ning soojuse tootmiseks. Kaart. Fotod. Skeem

Kolm maailma metallis / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Näitused Tallinnas: Maria Valdma "Võõrastemaja" Iida galeriis 31. jaan.-ni 2012, Kaie Partsi retrospektiivnäitus "Metall ja kivi" Vabaduse galeriis 6. dets.-ni 2011, Ülle Kõutsi "Vesi" A-Galeriis 5. dets.-ni 2011

Kõige moodsam janu / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Koostööst moekunstnike ja joogitootjate vahel. Prantsuse moekunstniku Jean-Paul Gaultier loomingust sündinud reklaamide seeriast Absolut Legends, Nathalie Rykieli disainitud Diet Coke'i pudelitest ning Jean-Paul Gaultier' ja Christian Lacroix' disainitud Eviani pudelitest

A randomized controlled trial with a Canadian electronic pill dispenser used to measure and improve medication adherence in patients with schizophrenia.

Science.gov (United States)

Stip, Emmanuel; Vincent, Philippe D; Sablier, Juliette; Guevremont, Catherine; Zhornitsky, Simon; Tranulis, Constantin

2013-01-01

Medication adherence is extremely important in preventing relapse and lowering symptoms in schizophrenic patients. However, estimates show that nearly half of these patients have poor adherence. The Brief Adherence Rating Scale (BARS) seems to be the most reliable tool assessing adherence in schizophrenia and shows that the antipsychotic adherence ratio (AAR) is about 49.5% in schizophrenia. The aim of the study was to test if an electronic pill dispenser named DoPill(®) improved AAR of schizophrenic patients. Furthermore, we compared AAR obtained by the DoPill(®) and the BARS, in order to verify whether the DoPill(®) provides reliable assessment of medication adherence. The DoPill(®) is a smart pill dispenser that beeps and flashes at the appropriate time of the day. Each of its 28 compartments is covered by a plastic lamina that, when taken off, sends a signal to the pharmacist. Patients were randomized to the DoPill(®) or treatment as usual groups for 6 weeks. The BARS was used as a reference measure. Forty-six percent of patients were deemed to be non-adherent with antipsychotic medication. The mean AAR was 67% after 6 weeks. DoPill(®) recorded better AAR than some of those found in the literature and were lower than the BARS estimate we found. These results suggest that DoPill(®) is a valid tool that provides more reliable and objective data for the clinician about their patient's adherence, than existing assessment tools like the BARS. Furthermore, the device may help patients successfully manage their medication regimen.

New erection program of the hydroelectric power plant Beznau. Das Neubauprojekt des hydraulischen Kraftwerkes Beznau

Energy Technology Data Exchange (ETDEWEB)

Bretscher, B; Hauenstein, W [NOK Nordostschweizerische Kraftwerke AG, Baden (Switzerland)

1992-02-21

The projected hydroelectric power plant at Beznau on the Aare river will produce about 43% more electric power than the present hydroelectric power plant. The water level and the buildings in the Aare will remain unchanged, so that the enviromental impact will be relativley slight. The project is in accordance with the building permit so that no adaptations on modifications will be required. (orig.).

Analysis of Feedback in after Action Reviews

Science.gov (United States)

1987-06-01

CONNTSM Page INTRODUCTIUN . . . . . . . . . . . . . . . . . . . A Perspective on Feedback. . ....... • • ..... • 1 Overviev of %,•urrent Research...part of their training program . The AAR is in marked contrast to the critique method of feedback which is often used in military training. The AAR...feedback is task-inherent feedback. Task-inherent feedback refers to human-machine interacting systems, e.g., computers , where in a visual tracking task

Electric potential structures of auroral acceleration region border from multi-spacecraft Cluster data

Science.gov (United States)

Sadeghi, S.; Emami, M. R.

2018-04-01

This paper studies an auroral event using data from three spacecraft of the Cluster mission, one inside and two at the poleward edge of the bottom of the Auroral Acceleration Region (AAR). The study reveals the three-dimensional profile of the region's poleward boundary, showing spatial segmentation of the electric potential structures and their decay in time. It also depicts localized magnetic field variations and field-aligned currents that appear to have remained stable for at least 80 s. Such observations became possible due to the fortuitous motion of the three spacecraft nearly parallel to each other and tangential to the AAR edge, so that the differences and variations can be seen when the spacecraft enter and exit the segmentations, hence revealing their position with respect to the AAR.

Ekspedeerimisfirmade TOP

Index Scriptorium Estoniae

2008-01-01

Ekspedeerimisfirmade TOP 57. Vt. samas: Tanel Raig. Majandus kukutab ekspedeerimisturgu. Diagramm: Väliskaubanduse statistika; Katrin Raie. Ekspedeerijad hakkavad rohkem koostööle rõhuma. Kommenteerib Jaan Lepp; Müügitulu TOP 10; Müügitulu kasvu TOP 10; Kasumi TOP 10; Kasumi kasvu TOP 10; Rentaabluse TOP 10; Omakapitali tootlikkuse TOP 10; Eestis registreeritud Vene hiiglane; Ekspedeerimisturu kasumiliider kaotas 20 miljonit; Küsimustele vastab OÜ Contimer juht Dmitri Redkin

Põhjamaade esteetika tumedam pool Londonis / Reet Rast

Index Scriptorium Estoniae

Rast, Reet, 1964-

2010-01-01

Londoni disainifestivali väljapanek "Was it a Dream?" ("Kas see oli unenägu?") Londonis (94 Berwick Street, Soho) 14.-24. septembrini 2010. Kuraator Merilyn Kesküla, kujundajad Merilyn Kesküla ja Paul Drummond. Eestlastest esinesid näitusel Kriss Soonik, Piret Kartus, Tanel Veenre, Tarmo Luisk, Jaanus Orgusaar, Kärt Ojavee ja Vinteco. Eesti kuraatori kureeritud näitus koondas Põhjamaade ja Eesti disainerite ja kunstnike loomingu

A randomized-controlled trial with a Canadian electronic pill dispenser used to measure and improve medication adherence in patients with schizophrenia

Directory of Open Access Journals (Sweden)

Emmanuel eStip

2013-08-01

Full Text Available Objective: Medication adherence is extremely important in preventing relapse and lowering symptoms in schizophrenic patients. However, estimates show that nearly half of these patients have poor adherence. The Brief Adherence Rating Scale (BARS seems to be the most reliable tool assessing adherence in schizophrenia and shows that the antipsychotic adherence ratio (AAR is about 49.5 % in schizophrenia. The aim of the study was to test if an electronic pill dispenser named DoPill® improved AAR of schizophrenic patients. Furthermore, we compared AAR obtained by the DoPill® and the BARS, in order to verify whether the DoPill® provides reliable assessment of medication adherence. Methods: The DoPill® is a smart pill dispenser that beeps and flashes at the appropriate time of the day. Each of its 28 compartments is covered by a plastic lamina that, when taken off, sends a signal to the pharmacist. Patients were randomized to the DoPill® or Treatment As Usual group (TAU for six weeks. The BARS was used as a reference measure. Results: Forty-six percent of patients were deemed to be non-adherent with antipsychotic medication. The mean AAR was 67 % after six weeks. DoPill® recorded better AAR than some of those found in the literature and were lower than the BARS estimate we found. Conclusion: These results suggest that DoPill® is a valid tool that provides more reliable and objective data for the clinician about their patient’s adherence, than existing assessment tools like the BARS. Furthermore, the device may help patients successfully manage their medication regimen.

Area at risk can be assessed by iodine-123-meta-iodobenzylguanidine single-photon emission computed tomography after myocardial infarction: a prospective study.

Science.gov (United States)

Hedon, Christophe; Huet, Fabien; Ben Bouallegue, Fayçal; Vernhet, Hélène; Macia, Jean-Christophe; Cung, Thien-Tri; Leclercq, Florence; Cade, Stéphane; Cransac, Frédéric; Lattuca, Benoit; Vandenberghe, D'Arcy; Bourdon, Aurélie; Benkiran, Meriem; Vauchot, Fabien; Gervasoni, Richard; D'estanque, Emmanuel; Mariano-Goulart, Denis; Roubille, François

2018-02-01

Myocardial salvage is an important surrogate endpoint to estimate the impact of treatments in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the correlation between cardiac sympathetic denervation area assessed by single-photon emission computed tomography (SPECT) using iodine-123-meta-iodobenzylguanidine (I-MIBG) and myocardial area at risk (AAR) assessed by cardiac magnetic resonance (CMR) (gold standard). A total of 35 postprimary reperfusion STEMI patients were enrolled prospectively to undergo SPECT using I-MIBG (evaluates cardiac sympathetic denervation) and thallium-201 (evaluates myocardial necrosis), and to undergo CMR imaging using T2-weighted spin-echo turbo inversion recovery for AAR and postgadolinium T1-weighted phase sensitive inversion recovery for scar assessment. I-MIBG imaging showed a wider denervated area (51.1±16.0% of left ventricular area) in comparison with the necrosis area on thallium-201 imaging (16.1±14.4% of left ventricular area, Parea (P=0.23) and was adequately correlated (R=0.56, P=0.0002). Myocardial salvage evaluated by SPECT imaging (mismatch denervated but viable myocardium) was significantly higher than by CMR (P=0.02). In patients with STEMI, I-MIBG SPECT, assessing cardiac sympathetic denervation may precisely evaluate the AAR, providing an alternative to CMR for AAR assessment.

The effect of alkali-aggregate reaction on concrete bridge structures

Directory of Open Access Journals (Sweden)

Grković Slobodan

2016-01-01

Full Text Available This paper shows contemporary issues related to unfavorable effects of concrete alkali-aggregate reaction (AAR on concrete bridge structures (CBS. Although AAR unfavorable effects on CBS were identified in 1930s, it was much later that AAR was acknowledged as one of the most pronounced deterioration processes in concrete that results in damages to concrete structures. There are two basic forms of AAR: alkali-silica reaction (ASR and alkali-carbonate reaction (ACR. Compared to ACR, ASR is more prominent, especially in certain geographic parts of the world. Damages to concrete caused by the ASR have negative effect primarily on usability and durability of CBS, what is followed by the decrease in load bearing capacity of structural components and reliability of the whole structure, shortening of service life (SL and costly repairs. For CBS, simultaneous occurrence of ASR and other degradation processes in concrete, such as those caused by the presence of moisture, water, temperature variations and use of deicing salt during winter, are especially damaging. Based on review of the most relevant literature, this paper is focused on mechanisms and mechanisms factors of the ASR, related contemporary research and reliability design guidelines for CBS that are based on prevention of the initiation and development of ASR.

Quantification of myocardial area at risk in the absence of collateral flow: the validation of angiographic scores by myocardial perfusion single-photon emission computed tomography.

Science.gov (United States)

Rodríguez-Palomares, José F; Alonso, Albert; Martí, Gerard; Aguadé-Bruix, Santiago; González-Alujas, M T; Romero-Farina, Guillermo; Candell-Riera, Jaume; García del Blanco, Bruno; Evangelista, Artur; García-Dorado, David

2013-02-01

Our study aimed to compare the area at risk (AAR) determined by single-photon emission computed tomography (SPECT) with the Bypass Angioplasty Revascularization Investigation (BARI) and modified Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) angiographic scores in the setting of patients undergoing coronary angioplasty for either unstable angina or an STEMI. Radionuclide myocardial perfusion imaging prior to reperfusion has classically been the most widely practised technique for assessing the AAR and has been successfully used to compare the efficacy of various reperfusion strategies in patients with an ST-segment elevation myocardial infarction (STEMI). The BARI and modified APPROACH scores are angiographic methods widely used to provide a rapid estimation of the AAR; however, they have not been directly validated with myocardial perfusion single-photon emission computed tomography (SPECT). Fifty-five patients with no previous myocardial infarction who underwent coronary angioplasty for single-vessel disease (unstable angina: n = 25 or an STEMI: n = 30) with no evidence of collaterals (Rentrop Collateral Score collateral flow, BARI and APPROACH scores constitute valid methods for AAR estimation in current clinical practice, with more accurate results when used for the LAD territory; both are useful not only in STEMI patients but also in patients with unstable angina.

Urban Combat Advanced Training Technology (Technologie avancee d’entrainement au combat urbain)

Science.gov (United States)

2015-07-01

For example, skills and drills (techniques) in an urban environment can be best trained or evaluated in a live environment, because other simulations...evidence as an AAR, and have the required skills to conduct an effective AAR. Some key 0 /C tasks are listed below. The precise tasks will be dependent...improvised “ Helpers ”, breaching material. Demo-Buildings and Showcases Detail of cut-away buildings, set-piece demonstrations and prepared rooms. STO

Loengud seaduseelnõude koostajaile / Margit Kikas

Index Scriptorium Estoniae

Kikas, Margit

2004-01-01

Eesti Juristide Liidu poolt koostöös Riigikantselei ja Justiitsministeeriumiga korraldatud loengusarjast: Õigusloome ja normitehnika: areng ja probleemid. Sõnavõtjad loengutel: Raul Narits, Katre Kont-Kontson, Lauri Mälksoo, Raigo Sõlg, Jüri Heinla, Anno Aedmaa, Aare Kasemets, Juhani Lemmik, Ülo Siivelt, Külli Koit, Aare Reenumägi, Mall Gramberg, Toomas Sepp, Julia Laffranque, Kristel Aguraiuja, Aime Vettik, Hille Saluäär, Hiie Tamm, Kristina Nõgols, Eve Randvere

The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment

OpenAIRE

Saint-L?ger, Ad?la?de; Sinadinos, Christopher; Ribas de Pouplana, Llu?s

2016-01-01

Malaria remains a major global health problem. Parasite resistance to existing drugs makes development of new antimalarials an urgency. The protein synthesis machinery is an excellent target for the development of new anti-infectives, and aminoacyl-tRNA synthetases (aaRS) have been validated as antimalarial drug targets. However, avoiding the emergence of drug resistance and improving selectivity to target aaRS in apicomplexan parasites, such as Plasmodium falciparum, remain crucial challenge...

Uued filmid: õiglus, õilsus ja maagiline kiiker / Kaarel Kressa

Index Scriptorium Estoniae

Kressa, Kaarel, 1983-

2011-01-01

Viru keskuse Katusekinos esilinastub 30. juunil Jaak Kilmi ja Kiur Aarma "Mattise martüürium". Lõppesid Eesti-Soome koostööptojekti "Rat King" võtted. Lõpevad Eesti-Läti-Valgevene ühistöö, "Peeter Simmi "Üksiku saare" võtted. Sellel aastal peaksid algama Ain Mäeotsa filmi "Deemonid", Kadri Kõusaare filmi "Euroopa psühho", Hardi Volmeri filmi "Remont" ja Kanadas Tanel Toomi filmi "Black Ice" võtted

3.-11. XI oli Edinburghi ECA Sculpture Court Balcony'l...

Index Scriptorium Estoniae

2005-01-01

Eesti päevade raames Kristi Paabi ja Maria Valdma kureeritud näitus "Rare Leid". Osalesid Kristiina Laurits, Villu Plink, Kaire Rannik, Mari Relo-Shaulys, Adolfas Shaulys, Anneli Tammik, Ketli Tiitsar ja Tanel Veenre. 3. XI ehtekunsti sümpoosionil Edinburghi kunstikolledzhis College of Artis esinesid loengutega Birgit Laken (Holland), K. Tiitsar ja T. Veenre. K. Paap ja M. Valdma juhendasid töötuba "Triibud või ruudud" ehtekunsti üliõpilastele

Attenuation of alpha2A-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood.

Science.gov (United States)

Shishkina, G T; Kalinina, T S; Dygalo, N N

2004-01-01

Brain alpha2-adrenergic receptors (alpha2-ARs) have been implicated in the regulation of anxiety, which is associated with stress. Environmental treatments during neonatal development could modulate the level of brain alpha2-AR expression and alter anxiety in adults, suggesting possible involvement of these receptors in early-life programming of anxiety state. The present study was undertaken to determine whether the reduction of the expression of A subtype of these receptors most abundant in the neonatal brain affects anxiety-related behavior in adulthood. We attenuated the expression of alpha2A-ARs during neonatal life by two different sequence specific approaches, antisense technology and RNA interference. Treatment of rats with the antisense oligodeoxynucleotide or short interfering RNA (siRNA) against alpha2A-ARs on the days 2-4 of their life, produced a marked acute decrease in the levels of both alpha2A-AR mRNA and [3H]RX821002 binding sites in the brainstem into which drugs were injected. The decrease of alpha2A-AR expression in the neonatal brainstem influenced the development of this receptor system in the brain regions as evidenced by the increased number of [3H]RX821002 binding sites in the hypothalamus of adult animals with both neonatal alpha2A-AR knockdown treatments; also in the frontal cortex of antisense-treated, and in the hippocampus of siRNA-treated adult rats. These adult animals also demonstrated a decreased anxiety in the elevated plus-maze as evidenced by an increased number of the open arm entries, greater proportion of time spent in the open arms, and more than a two-fold increase in the number of exploratory head dips. The results provide the first evidence that the reduction in the brain expression of a gene encoding for alpha2A-AR during neonatal life led to the long-term neurochemical and behavioral alterations. The data suggests that alterations in the expression of the receptor-specific gene during critical periods of brain

A randomized controlled trial with a Canadian electronic pill dispenser used to measure and improve medication adherence in patients with schizophrenia

OpenAIRE

Stip, Emmanuel; Vincent, Philippe D.; Sablier, Juliette; Guevremont, Catherine; Zhornitsky, Simon; Tranulis, Constantin

2013-01-01

Objective: Medication adherence is extremely important in preventing relapse and lowering symptoms in schizophrenic patients. However, estimates show that nearly half of these patients have poor adherence. The Brief Adherence Rating Scale (BARS) seems to be the most reliable tool assessing adherence in schizophrenia and shows that the antipsychotic adherence ratio (AAR) is about 49.5% in schizophrenia. The aim of the study was to test if an electronic pill dispenser named DoPill® improved AAR...

α(2A)-adrenergic receptors filter parabrachial inputs to the bed nucleus of the stria terminalis.

Science.gov (United States)

Flavin, Stephanie A; Matthews, Robert T; Wang, Qin; Muly, E Chris; Winder, Danny G

2014-07-09

α2-adrenergic receptors (AR) within the bed nucleus of the stria terminalis (BNST) reduce stress-reward interactions in rodent models. In addition to their roles as autoreceptors, BNST α(2A)-ARs suppress glutamatergic transmission. One prominent glutamatergic input to the BNST originates from the parabrachial nucleus (PBN) and consists of asymmetric axosomatic synapses containing calcitonin gene-related peptide (CGRP) and vGluT2. Here we provide immunoelectron microscopic data showing that many asymmetric axosomatic synapses in the BNST contain α(2A)-ARs. Further, we examined optically evoked glutamate release ex vivo in BNST from mice with virally delivered channelrhodopsin2 (ChR2) expression in PBN. In BNST from these animals, ChR2 partially colocalized with CGRP, and activation generated EPSCs in dorsal anterolateral BNST neurons that elicited two cell-type-specific outcomes: (1) feedforward inhibition or (2) an EPSP that elicited firing. We found that the α(2A)-AR agonist guanfacine selectively inhibited this PBN input to the BNST, preferentially reducing the excitatory response in ex vivo mouse brain slices. To begin to assess the overall impact of α(2A)-AR control of this PBN input on BNST excitatory transmission, we used a Thy1-COP4 mouse line with little postsynaptic ChR2 expression nor colocalization of ChR2 with CGRP in the BNST. In slices from these mice, we found that guanfacine enhanced, rather than suppressed, optogenetically initiated excitatory drive in BNST. Thus, our study reveals distinct actions of PBN afferents within the BNST and suggests that α(2A)-AR agonists may filter excitatory transmission in the BNST by inhibiting a component of the PBN input while enhancing the actions of other inputs. Copyright © 2014 the authors 0270-6474/14/349319-13$15.00/0.

Automatic localization of IASLC-defined mediastinal lymph node stations on CT images using fuzzy models

Science.gov (United States)

Matsumoto, Monica M. S.; Beig, Niha G.; Udupa, Jayaram K.; Archer, Steven; Torigian, Drew A.

2014-03-01

Lung cancer is associated with the highest cancer mortality rates among men and women in the United States. The accurate and precise identification of the lymph node stations on computed tomography (CT) images is important for staging disease and potentially for prognosticating outcome in patients with lung cancer, as well as for pretreatment planning and response assessment purposes. To facilitate a standard means of referring to lymph nodes, the International Association for the Study of Lung Cancer (IASLC) has recently proposed a definition of the different lymph node stations and zones in the thorax. However, nodal station identification is typically performed manually by visual assessment in clinical radiology. This approach leaves room for error due to the subjective and potentially ambiguous nature of visual interpretation, and is labor intensive. We present a method of automatically recognizing the mediastinal IASLC-defined lymph node stations by modifying a hierarchical fuzzy modeling approach previously developed for body-wide automatic anatomy recognition (AAR) in medical imagery. Our AAR-lymph node (AAR-LN) system follows the AAR methodology and consists of two steps. In the first step, the various lymph node stations are manually delineated on a set of CT images following the IASLC definitions. These delineations are then used to build a fuzzy hierarchical model of the nodal stations which are considered as 3D objects. In the second step, the stations are automatically located on any given CT image of the thorax by using the hierarchical fuzzy model and object recognition algorithms. Based on 23 data sets used for model building, 22 independent data sets for testing, and 10 lymph node stations, a mean localization accuracy of within 1-6 voxels has been achieved by the AAR-LN system.

Pariisis jagati Cesare / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Sel aastal sai prantsuse rahvuslike filmiauhindade Cesaride jagamisel kõige enam (8) auhindu J. Audiard'i mängufilm "Mu süda jättis vahele löögi" ("De battre mon coeur s'est arrete"). Näitlejapreemiad said Michel Bouquet, Nathalie Baye

Werner Herzog Tallinnas / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2002-01-01

Detsembris toimuvat Pimedate Ööde Filmifestivali laiendatakse ka suvele, et sobivates paikades näidata väärtfilme. Alates 6. juunist näidatakse Katariina kirikus kuuel õhtul algusega kell 22 Werner Herzogi (1942) filme. Režissöörist ja näidatavatest filmidest

Retrofilm kultusõudukast / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2004-01-01

Mängufilm "Vampiiri vari" ("The Shadow of the Vampire") : režissöör E. Elias Merhige : Ameerika Ühendriigid - Suurbritannia 2000. Inspireerituna samast F.W. Murnau õudusfilmist "Nosferatu, õuduste sümfoonia" (1922), oli ka Werner Herzog loonud 1978.a. filmi "Nosferatu - öö fantoom"

Pattulangemine ja lunastus / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2005-01-01

PÖFFi filme - "Taevane lahing" ("Batalla en el cielo" : režissöör Carlos Reygadas : Mehhiko - Prantsusmaa - Saksamaa - Belgia 2005, "Valede kammitsas" ("Separate Lies") : Nigel Balchini rom. "A Way Through the Wood" järgi režissöör Julian Fellowes : Suurbritannia 2005

Tõeline Crocodile Dundee / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

4. sept. hukkus veealuse dokfilmi võtetel Austraalia loodusuurija, loomakaitsja, telekanali Animal Planet sarja "Krokodillikütt" ("Crocodile Hunter") populaarne autor ja esineja Steve Irwin (1962-2006)

Almodovari esimesed katsetused / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Pedro Almodovarile tehti ettepanek restaureerida oma esimesi eksperimentaalseid katsetusi "Kaks hoora / Armastuslugu, mis lõpeb pulmadega" (1974), "Seks tuleb, seks läheb" (1977), Soodoma lõpp (1979)

Vabaduse tuuled Ungarist / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Sõpruse kinos algab homme filmiprogramm "Vabaduse tuuled" Ungari 1956.a. ülestõusule pühendatud mängufilmide programm (6 ungari filmi aastaist 1965-2004) : Ungari Instituudi, kino "Sõprus" ja PÖFFi koostööprojekt

Veebruarikuus 2000 lahkunuid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2000-01-01

Surid : Autant-Lara, Claude prantsuse režissöör (5.08.1903-5.02.2000), Vadim, Roger ukraina päritolu prantsuse režissöör (26.01.1928-11.02.2000), Kedrova, Lila vene päritolu prantsuse näitlejanna (1918-16.02.2000), Martelli, Otello itaalia filmioperaator (19.05.1903-20.02.2000)

Feodaalne verepulm teleekraanil / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2011-01-01

Alates 8. septembrist Fox Life'i eestikeelsel kanalil jooksma hakkavast George R. R. Martini raamatul põhinevast USA telekanali HBO telesarjast "Troonide mäng" (sarja loojad David Benioff ja Dan Weiss)

Automatic anatomy recognition on CT images with pathology

Science.gov (United States)

Huang, Lidong; Udupa, Jayaram K.; Tong, Yubing; Odhner, Dewey; Torigian, Drew A.

2016-03-01

Body-wide anatomy recognition on CT images with pathology becomes crucial for quantifying body-wide disease burden. This, however, is a challenging problem because various diseases result in various abnormalities of objects such as shape and intensity patterns. We previously developed an automatic anatomy recognition (AAR) system [1] whose applicability was demonstrated on near normal diagnostic CT images in different body regions on 35 organs. The aim of this paper is to investigate strategies for adapting the previous AAR system to diagnostic CT images of patients with various pathologies as a first step toward automated body-wide disease quantification. The AAR approach consists of three main steps - model building, object recognition, and object delineation. In this paper, within the broader AAR framework, we describe a new strategy for object recognition to handle abnormal images. In the model building stage an optimal threshold interval is learned from near-normal training images for each object. This threshold is optimally tuned to the pathological manifestation of the object in the test image. Recognition is performed following a hierarchical representation of the objects. Experimental results for the abdominal body region based on 50 near-normal images used for model building and 20 abnormal images used for object recognition show that object localization accuracy within 2 voxels for liver and spleen and 3 voxels for kidney can be achieved with the new strategy.

Effects of Silodosin and Tamsulosin on the Seminal Vesicle Contractile Response.

Science.gov (United States)

Hayashi, Tokumasa; Takeya, Mitsue; Nakamura, Kei-ichiro; Matsuoka, Kei

2016-01-01

To understand the mechanisms underlying ejaculation dysfunction caused by α1A-adrenocetor (AR) antagonists, the effects of α1A-AR antagonists on the contractile responses of the seminal vesicle were investigated. Isolated seminal vesicles from guinea pigs were cannulated and pressurized, and the changes in the intraluminal pressure were recorded. Periodic applications of electrical stimulation (ES) caused biphasic increase in the intraluminal pressure, that is, initial and subsequent contractions. The effects of silodosin and tamsulosin, α1A-AR antagonists, on the contractile responses were examined. The ES-induced biphasic contractions were blocked by tetrodotoxin (TTX). Silodosin and tamsulosin suppressed the initial contractions in a dose-dependent manner, while also exerting various inhibitory effects on the subsequent contractions. Increases in the intraluminal pressure facilitated spontaneous phasic contractions. The spontaneous contractions were not affected by TTX or α1A-AR antagonists, but were abolished by nifedipine. The initial contractions triggered by neuronal excitations were suppressed by silodosin and tamsulosin, suggesting that the ejaculation dysfunction may be attributed to the α1A-AR antagonist-mediated suppression of nerve-evoked contractions in the seminal vesicle. The subsequent contractions may be induced by mechanical stimulation associated with the initial, nerve-evoked contractions. Alternatively, other transmitters may be involved to various degrees in the neuromuscular transmission of the seminal vesicle. © 2014 Wiley Publishing Asia Pty Ltd.

Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases

Science.gov (United States)

Haupt, V. Joachim; Schroeder, Michael; Labudde, Dirk

2018-01-01

The origin of the machinery that realizes protein biosynthesis in all organisms is still unclear. One key component of this machinery are aminoacyl tRNA synthetases (aaRS), which ligate tRNAs to amino acids while consuming ATP. Sequence analyses revealed that these enzymes can be divided into two complementary classes. Both classes differ significantly on a sequence and structural level, feature different reaction mechanisms, and occur in diverse oligomerization states. The one unifying aspect of both classes is their function of binding ATP. We identified Backbone Brackets and Arginine Tweezers as most compact ATP binding motifs characteristic for each Class. Geometric analysis shows a structural rearrangement of the Backbone Brackets upon ATP binding, indicating a general mechanism of all Class I structures. Regarding the origin of aaRS, the Rodin-Ohno hypothesis states that the peculiar nature of the two aaRS classes is the result of their primordial forms, called Protozymes, being encoded on opposite strands of the same gene. Backbone Brackets and Arginine Tweezers were traced back to the proposed Protozymes and their more efficient successors, the Urzymes. Both structural motifs can be observed as pairs of residues in contemporary structures and it seems that the time of their addition, indicated by their placement in the ancient aaRS, coincides with the evolutionary trace of Proto- and Urzymes. PMID:29659563

Lõigutud aeg / Vappu Thurlow

Index Scriptorium Estoniae

Thurlow, Vappu, 1960-

2007-01-01

Adamson-Ericu muuseumis kuni 25. XI avatud näitusest "Lõigutud aeg". Henri Bergsoni ajakäsitlusest. Töödest: Anu Juuraku "Suplejad", Ilkka Väätti "Kinaalda" ja "Ton", Aili Vahtrapuu "Vaagen vabale vaimule", Marje Üksise "Nii ma lähen", Annemie Bogaerts'i "Lõpp on vaikus", Siim-Tanel Annuse "24 tundi", Lynne Allen'i "Saak", Eve Kiileri "Ilu etalonide arhiivid", Ingrid Ledent'i "Mälu kestev olemine, mis muudab mineviku olevikuks", Raoul Kurvitza "Aeg ja lugu"

Validation of Contrast Enhanced Cine Steady-State Free Precession and T2-Weigthed CMR for Assessment of Ischemic Myocardial Area- At-Risk

DEFF Research Database (Denmark)

Søvsø Szocska Hansen, Esben; Pedersen, Steen Fjord; Pedersen, Steen Bønløkke

2017-01-01

-CINE) has recently been used to quantify AAR and validated against myocardial perfusion SPECT. In this study we sought to determine how well T2-STIR and CE-CINE depicts AAR in an experimental porcine model of myocardial ischemia-reperfusion injury using histopathology as the reference for infarct size......Measuring myocardial salvage is important to evaluate the possible cardioprotective effects of adjunctive cardioprotective intervention in patients with myocardial infarction undergoing primary percutaneous intervention. Contrast-enhanced steady-state free precession magnetic resonance imaging (CE...

Kus on disaini Youtube? / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Tallinna 5. rakenduskunsti triennaali peanäitus "Know how" Eesti Tarbekunsti- ja Disainimuuseumis kuni 21. 02. 2010. Kuraator Kärt Maran, kujundajad Ott Kadarik ja Tuuli Aule. Kolm võrdset preemiat suurusega á 20000 Eesti krooni pälvisid Marta Boan (Hispaania) ehete seeria "Cube" eest, autorite kollektiiv Jaan Evart (Eesti), Julian Hagen (Austria) ja Daniel Maarleveld (Holland) töö "Penjet" eest, Kieren Jones (Suurbritannia) tööde seeria "IDEA-Flat Pack Re-arranged: Gopan, Strum, Gunn, Trophi" eest

Ideede paraad Zürichis / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2000-01-01

Üleeuroopaline noorte moeloojate etendus Barclay-Catwalk Zürichis ja Rotterdamis. Uued nimed: Wei Gao, Natasha ja Tamara Surguladze, Jacqueline Burtsche, Tom Notte, Jessy Heuvelink, Daniel Controversio jt.

Kaunilt kujundatud aken tulevikku / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

IDEA (International Design Excellence Awards) 2009. aasta disainivõistlusest. Võidutsesid tooted, mis on mõeldud elujärje parandamiseks vaesemates piirkondades ja taaskasutus. Edukamad osalejad firmad olid Samsung (8 auhinda) ja Apple (7 auhinda)

Virtuaalmuuseum Egiptuses / Ra Luhse, Tanel Tuhal

Index Scriptorium Estoniae

Luhse, Ra, 1964-

2003-01-01

Suure Egiptuse Muuseumi rahvusvaheline arhitektuurivõistlus Kairos autorite osalusel. Eestlaste töö jõudis 200 hulka ja avaldati kataloogis. Võidu- ja äramärgitud tööde iseloomustus. Võitis Iiri arhitektibüroo Henegan-Peng Architects

Hea uus Eesti ilm / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2008-01-01

Eesti kultuurist, uuest rahvuslikust tõusust muusikas (folgifestivalid, folk-metal muusika, öölaulupeod), moes (rahvariiete buum, Aldo Järvsoo kollektsioon Folkcouture, noorte moekunstnike tööd Supernooval), filmis ja teatris (Taarka, Anton Hansen Tammsaare suvelavastused, Pärimusteater Loomine), arhitektuuris, kirjanduses ja kokakunstis

Kas Haapsalu asub Marsil? / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Prantsuse kunstnike Nicolas Schneideri ja Antoine Lejolivet' näitus "Ükskord me kõnnime Marsil" ehk "On ira marcher sur Mars" Haapsalus Evald Okase muuseumis 31. augustini 2011. Näitusele eelnes kunstnike kahenädalane residentuur muuseumis. Projekti eestvedaja Mara Koppel-Ljutjuk

Appi, kas Narvat kiusatakse? / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Ilmunud ka: Narva Postiljon 19. juuli lk. 2, Molodjozh Estonii 22. juuli lk. 2. Autor viitab Narva linnavolikogu esimehe Mihhail Stalnuhhini reageeringule seoses õiguskaitseorganite esitatud korruptsioonikahtlusega Narvas ning arvab, et tuntud poliitik on rahvusküsimuse ja korruptsiooni ühte patta pannud

Ksenofoobia kui rahvuslik uhkus / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Eestlaste võõrastekartusest. Autori hinnangul oleme olukorras, kus vaid sadakond aastat tagasi ise koloonia staatusest vabanenuna peame hakkama käituma samaväärselt postkoloniaalsete suurriikidega

Kargelt kosmilised vineerivõnked / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Näitus ""Veneer MG" - Maile Grünbergi poolt kujundatud mööbel painutatud kasevineerist" Tallinnas Arhitektuuri- ja Didainigaleriis. Kaubamärk "Veneer MG" sündis ettevõtte Aja Nägu OÜ ja didainer Maile Grünbergi koostöös

Gilbert Arenas ekstravertne introvert / Tanel Kapp

Index Scriptorium Estoniae

Kapp, Tanel

2006-01-01

NBA ühest ekstsentrilisemast mängijast, kes on meedia tähelepanu keskmes olnud juba esimesest hooajast peale, ent seda eelkõige oma pöörase käitumise ja koomiliste kommentaaride tõttu. Lisa: Statistika

Moodne Magnum kasutab tipptaset / Tanel Raig

Index Scriptorium Estoniae

Raig, Tanel, 1975-

2008-01-01

Logistikateo konkursil esikoha saanud Magnum Logisticsi uus ladu on omataolistest Ida-Euroopas moodsaim. Vt. samas: Aasta logistikateo finaali jõudnud tööd olid suunatud efektiivsusele. Kommenteerivad Erki Lehiste ja Indrek Reismann

Disainilugu metallis ja tekstiilis / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Tekstiilikunstniku Hilja Kullese juubelinäitus "Õhtu" Eesti Tarbekunsti- ja Disanimuuseumis. Näitus "Roman Tavasti juveelifirma koolimärgid 1923-2010" Tallinna Arhitektuuri- ja Disainigaleriis. Keraamik Leo Rohlini näitus "Nokturn" Hop-galeriis

Opportunities Missed: A Cross-Sectional Survey of the Provision of Smoking Cessation Care to Pregnant Women by Australian General Practitioners and Obstetricians.

Science.gov (United States)

Zeev, Yael Bar; Bonevski, Billie; Twyman, Laura; Watt, Kerrianne; Atkins, Lou; Palazzi, Kerrin; Oldmeadow, Christopher; Gould, Gillian S

2017-05-01

Similar to other high-income countries, smoking rates in pregnancy can be high in specific vulnerable groups in Australia. Several clinical guidelines exist, including the 5A's (Ask, Advice, Assess, Assist, and Arrange), ABCD (Ask, Brief advice, Cessation, and Discuss), and AAR (Ask, Advice, and Refer). There is lack of data on provision of smoking cessation care (SCC) of Australian General Practitioners (GPs) and Obstetricians. A cross-sectional survey explored the provision of SCC, barriers and enablers using the Theoretical Domains Framework, and the associations between them. Two samples were invited: (1) GPs and Obstetricians from a college database (n = 5571); (2) GPs from a special interest group for Indigenous health (n = 500). Dimension reduction for the Theoretical Domains Framework was achieved with factor analysis. Logistic regression was carried out for performing all the 5A's and the AAR. Performing all of the 5A's, ABCD, and AAR "often and always" was reported by 19.9%, 15.6%, and 49.2% respectively. "Internal influences" (such as confidence in counselling) were associated with higher performance of the 5A's (Adjusted OR 2.69 (95% CI 1.5, 4.8), p workplace routine) were associated with higher performance of AAR (Adjusted OR 1.7 (95% CI 1, 2.8), p = .035). Performance in providing SCC to pregnant women is low among Australian GPs and Obstetricians. Training clinicians should focus on improving internal influences such as confidence and optimism. The AAR may be easier to implement, and interventions at the service level should focus on ensuring easy, effective, and acceptable referral mechanisms are in place. Improving provision of the 5A's approach should focus on the individual level, including better training for GPs and Obstetricians, designed to improve specific "internal" barriers such as confidence in counselling and optimism. The AAR may be easier to implement in view of the higher overall performance of this approach. Interventions on a more

"Matsi leivamärss" : elamukvartal Papli tänaval Pärnus = Papli St. Residential Area in Pärnu / Karri Tiigisoon

Index Scriptorium Estoniae

Tiigisoon, Karri

2004-01-01

Ka hotell-veekeskusest "Tervise Paradiis", parklast, AB Luhse & Tuhal poolt koostatud ja 2000. a. kehtestatud Side t., A. H. Tammsaare pst., Mai t. elamurajooni ja merekalda vahelise ala detailplaneeringust. 2003.-2004. aastatel valminud Papli t. kahekorruselised korterelamud projekteerisid arhitektid Raivo Puusepp (Papli t. 32, AB Raivo Puusepp), Kalle Vellevoog (Papli t. 34, AB JVR), Tanel Tuhal ja Ra Luhse (Papli t. 20, 22, 24, 26, 28, 30, AB Luhse & Tuhal). Ill.: 4 plaani, 8 värv. välisvaadet

Insulin-increased L-arginine transport requires A(2A adenosine receptors activation in human umbilical vein endothelium.

Directory of Open Access Journals (Sweden)

Enrique Guzmán-Gutiérrez

Full Text Available Adenosine causes vasodilation of human placenta vasculature by increasing the transport of arginine via cationic amino acid transporters 1 (hCAT-1. This process involves the activation of A(2A adenosine receptors (A(2AAR in human umbilical vein endothelial cells (HUVECs. Insulin increases hCAT-1 activity and expression in HUVECs, and A(2AAR stimulation increases insulin sensitivity in subjects with insulin resistance. However, whether A(2AAR plays a role in insulin-mediated increase in L-arginine transport in HUVECs is unknown. To determine this, we first assayed the kinetics of saturable L-arginine transport (1 minute, 37°C in the absence or presence of nitrobenzylthioinosine (NBTI, 10 µmol/L, adenosine transport inhibitor and/or adenosine receptors agonist/antagonists. We also determined hCAT-1 protein and mRNA expression levels (Western blots and quantitative PCR, and SLC7A1 (for hCAT-1 reporter promoter activity. Insulin and NBTI increased the extracellular adenosine concentration, the maximal velocity for L-arginine transport without altering the apparent K(m for L-arginine transport, hCAT-1 protein and mRNA expression levels, and SLC7A1 transcriptional activity. An A2AAR antagonist ZM-241385 blocked these effects. ZM241385 inhibited SLC7A1 reporter transcriptional activity to the same extent in cells transfected with pGL3-hCAT-1(-1606 or pGL3-hCAT-1(-650 constructs in the presence of NBTI + insulin. However, SLC7A1 reporter activity was increased by NBTI only in cells transfected with pGL3-hCAT-1(-1606, and the ZM-241385 sensitive fraction of the NBTI response was similar in the absence or in the presence of insulin. Thus, insulin modulation of hCAT-1 expression and activity requires functional A(2AAR in HUVECs, a mechanism that may be applicable to diseases associated with fetal insulin resistance, such as gestational diabetes.

Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression

Directory of Open Access Journals (Sweden)

Hong-ping Huang

2017-05-01

Full Text Available Chronic stressors can often lead to the development of psychological disorders, such as depression and anxiety. The locus coeruleus (LC is a stress sensitive brain region located in the pons, with noradrenergic neurons that project to the hypothalamus, especially the paraventricular nucleus (PVN of the hypothalamus. The purpose of this paper is to better understand how alpha 2A-adrenoceptors (α2A-ARs and LC-hypothalamus noradrenergic system participate in the pathophysiological mechanism of depression. In vivo norepinephrine (NE release in the PVN triggered by electrical stimulation in the LC was detected with carbon fiber electrodes in depression model of rats induced by chronic unpredictable mild stress (CUMS. Also, the extracellular level of NE in the PVN was measured by microdialysis in vivo without any stimulation in the LC. The alpha 2-adrenoceptor (α2-AR antagonist yohimbine and α2A-ARs antagonist BRL-44408 maleate were systemically administered to rats to determine the effects of α2A-ARs on NE release in the PVN. The peak value of elicited NE release signals in the PVN induced by electrical stimulation in the LC in the CUMS rats were lower than that in the control rats. The extracellular levels of NE in the PVN of the CUMS rats were significantly less than that of the control rats. Intraperitoneal injection of yohimbine or BRL-44408 maleate significantly potentiated NE release in the PVN of the CUMS rats. The CUMS significantly increased protein expression levels of α2A-AR in the hypothalamus, and BRL-44408 maleate significantly reversed the increase of α2A-AR protein expression levels in the CUMS rats. Our results suggest that the CUMS could significantly facilitate the effect of α2-adrenoceptor-mediated presynaptic inhibition and decrease the release of NE in the PVN from LC. Blockade of the inhibitory action of excessive α2A-adrenergic receptors in the CUMS rats could increase the level of NE in the PVN, which is effective in

Aare Anderson : Elva-taoline väikelinn on parimaid kohti elamiseks / Aare Anderson ; interv. Mare Nõmmik

Index Scriptorium Estoniae

Anderson, Aare, 1966-

2006-01-01

Elva endine linnapea ja aselinnapea, rahandusministeeriumi töötaja vastab küsimustele, mis on seotud tema ametikohaga, Elvaga, võimalusega siduda end tulevikus poliitikaga. Isamaa ja Res Publica Liidu loosungist "Õnn ei ole rahas"

Automated Aerial Refueling Hitches a Ride on AFF

Science.gov (United States)

Hansen, Jennifer L.; Murray, James E.; Bever, Glenn; Campos, Norma V.; Schkolnik, Gerard

2007-01-01

The recent introduction of uninhabited aerial vehicles [UAVs (basically, remotely piloted or autonomous aircraft)] has spawned new developments in autonomous operation and posed new challenges. Automated aerial refueling (AAR) is a capability that will enable UAVs to travel greater distances and loiter longer over targets. NASA Dryden Flight Research Center, in cooperation with the Defense Advanced Research Projects Agency (DARPA), the Naval Air Systems Command (NAVAIR), the Naval Air Force Pacific Fleet, and the Air Force Research Laboratory, rapidly conceived and accomplished an AAR flight research project focused on collecting a unique, high-quality database on the dynamics of the hose and drogue of an aerial refueling system. This flight-derived database would be used to validate mathematical models of the dynamics in support of design and analysis of AAR systems for future UAVs. The project involved the use of two Dryden F/A-18 airplanes and an S-3 hose-drogue refueling store on loan from the Navy. In this year-long project, which was started on October 1, 2002, 583 research maneuvers were completed during 23 flights.

Kunstnike Liit

Index Scriptorium Estoniae

2004-01-01

EKLi volikogu töökoosolek 5. IV. SA ERF alllfondina loodud Olev Soansi mälestusfondi toetamisest, EKLi 2005. a. aastanäituse korraldamisest Tallinna Kunstihoones, vajalikest täiendustest ja muudatustest põhikirjas, mis puudutavad tehinguid Tallinna Kunstihoone ja selle galeriiga. Võeti vastu tööjuhised SA Tallinna Kunstihoone Fondi nõukogule. EKLi uued liikmed: Kaarel Eelma, Piret Hirv, Sandra Jõgeva, Irene Jürna, Kristin Kalamees, Kristiina Laurits, Eve Margus-Villems, Villu Plink, Lembe Ruben, Katrin Sipelgas, Margus Tamm, Tanel Veenre

Anomalous rostral lumbosacral root emergence from the thecal sac

International Nuclear Information System (INIS)

Peyster, R.G.; Parghi, A.; Siegal, T.; Hershey, B.L.; Yablon, J.; Jaffe, S.

1989-01-01

Anomalous rostral lumbosacral root emergence (AARE) has important clinical implications and has received little attention. The authors have studied the occurrence of this anomaly and presentation of cases in which it was paramount in causing radiculopathy. AARE was noted with the following occurrence rates in 500 cases: L3, 0%; L4, 1%; L5, 9%, and S1, 16%. In ARRE, the roots lie laterally between the superior facet and the annulus and are subject to compression by minimal disk bulging or facet hypertrophy. One must track the individual nerve roots on lumbar CT and MR imaging to detect this subtle condition

Script Identification from Printed Indian Document Images and Performance Evaluation Using Different Classifiers

Directory of Open Access Journals (Sweden)

Sk Md Obaidullah

2014-01-01

multiscript country like India. In this paper the real life problem of printed script identification from official Indian document images is considered and performances of different well-known classifiers are evaluated. Two important evaluating parameters, namely, AAR (average accuracy rate and MBT (model building time, are computed for this performance analysis. Experiment was carried out on 459 printed document images with 5-fold cross-validation. Simple Logistic model shows highest AAR of 98.9% among all. BayesNet and Random Forest model have average accuracy rate of 96.7% and 98.2% correspondingly with lowest MBT of 0.09 s.

Accelerator assisted repositories, technical issue identification and economic assessment

Energy Technology Data Exchange (ETDEWEB)

Myers, T.; Favale, A.; Berwald, D. [Northrop Grumman Corp., Bethpage, NY (United States)

1995-12-31

An investigation (technical and economic) is presented to quantify the impact of accelerator assisted repository (AAR) system on the US national nuclear repository strategy. An overview of US spent fuel policy is presented which provides a means to comparatively assess competing spent fuel disposition technologies under investigation. The advantages of an AAR system are highlighted and discussed. A companion economic analysis is presented. The results indicate that although a US geologic waste repository will continue to be required, waste partitioning and accelerator transmutation of selected actinides, and long-lived fission products, can result in substantial benefits. (author) 18 refs.

Kontsert

Index Scriptorium Estoniae

2005-01-01

Vanemuise kontserdimajas 11. nov. isadepäeva kontserdil "Isad ja pojad" esinemas Olav Ehala ja Tanel Ehala klaveril ja Pärnu Linnaorkester, kaastegev Kiigelaulukuuik (dirigent Erki Pehk). 12. nov. kammerlaval festivalil "Fiesta de la guitarra '05" kitarriduo Katona Twins, 17. nov. Aleksander Rudini ja Tallinna Kammerorkestri kontsert. TÜ aulas 11. nov. kitarrikontsert: Rody van Gemert & Mikko Ikäheimo, 13. nov. "Fiesta de la guitarra '05" pidulik gala. TÜ ajaloo muuseumis 14. nov. Elleri Muusikakooli kontsert "Sügisbarokk". Jaani kirikus 13. nov. festivalil "Fiesta de la guitarra '05" Miguel Rivera ja Luis Carro Barquero

Saaremaa Fond turgutab õppureid / Aare Laine

Index Scriptorium Estoniae

Laine, Aare, 1951-

2012-01-01

Saaremaa Fond andis kõrgkoolides häid õpitulemusi näidanud ja pere kõrvalt õppivatele tudengitele üle aastastipendiumid. Õppiva pere stipendium: Viljandi kultuuriakadeemias rahvuslikku käsitööd õppiv Alliki Oidekivi, Tallinna ülikoolis 2. kursusel kutsepedagoogikat õppiv Ahti Paju ning Tallinna ülikoolis magistriõppes haridustehnoloogiat õppiv Irena Sink. Peeter Palu nimeline stipendium: Eesti mereakadeemia tüürimehe eriala 2. kursuse tudengile Ott Kuusele. Tallinna Sadama nimelise stipendium: mereakadeemias tüürimehe eriala õppiv Dmitri Mišin

Poeetilisest mõõtmest / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2016-01-01

Luule tõlkimisest, selgitades mõistet "poeetiline mõõde". Artikli teises pooles käsitletakse ka sama keeleruumi klassikaliste luuletuste tõlkimist tänapäeva keelde, kasutades Aleksandr Puškini luuletuse "A. P. Kernile" näidet

Digitaalallkirja seadus saab sisu / Aare Reivart

Index Scriptorium Estoniae

Reivart, Aare, 1968-

2000-01-01

Sideoperaatorid ja pangad hakkavad välja töötama ühtset avalikku võtme infrastruktuuri (PKI), mis võimaldab telefoni ja interneti vahendusel kasutada mitmesuguseid teenuseid kiiresti ja turvaliselt

Poola teadlane uurib kraatrit / Aare Laine

Index Scriptorium Estoniae

Laine, Aare, 1951-

2004-01-01

Poznani ülikooli geoloogiainstituudi direktor Wojciech Stankowaki koos tudengitega võtab pinnaseproove edasiseks uurimiseks. Kahe riigi koostöö toimub mõlema riigi teaduste akadeemia ühisprogrammi "Eesti ja Poola meteoriidikraatrite võrdlev uurimine" alusel

Kõik algas tinapanekuga saunas / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Eldar Rjazanov ja tema aastavahetuse menufilmid. "Saatuse iroonia ehk Hüva leili!" (1975) järjefilm "Saatuse iroonia: lugu läheb edasi" ("Ironija sudbõ. Prodolzhenije") : režissöör Timur Bekmambetov : Venemaa 2007

Avariide kiuste Monte Carlosse / Aare Arula

Index Scriptorium Estoniae

Arula, Aare

2007-01-01

Vt. ka Tehnika dlja Vsehh nr. 3, lk. 26-27. 26. jaanuaril 1937 Tallinnast Monte Carlo tähesõidule startinud Karl Siitanit ja tema meeskonda ootasid ees seiklused, mis oleksid neile peaaegu elu maksnud

Silmatagusest teatrist / Sirle Põdersoo, Aare Pilv

Index Scriptorium Estoniae

Põdersoo, Sirle

2003-01-01

J. Tombergi ja Andreas W "Aurora temporalis" H. Toompere jun lavastuses Tartu Sadamateatris, Lendava Hollandlase ja Tartu Teatrilabori projekt ning "Maja Jaama uulitsas" M. Heinsaare juttude põhjal Tartu Teatrilaboris, projektijuht J. Jaanus, lavastus ja tants T. Mölder, H. Reitsnik, K. Essenson, E. Ülevain, M. Plakso, A. Vamper

Lugu, milles puuduvad kangelased / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

W.M. Thackeray (1811-1863) romaani "Edevuse laat" ekraniseeringutest. Lähemalt Suurbritannias 1998. aastal valminud 6-osalisest teleseriaalist ja selle kesksetest osatäitjatest. Ka : Teleleht nr. 6, lk. 36-38

Ise kaklevad, ise lepivad / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

Mängufilm "Kes kardab Virginia Woolfi?" ("Who's Afraid Of Virginia Woolf?") : stsenarist Ernest Lehman Edward Albee näidendi järgi : režissöör Mike Nichols : Ameerika Ühendriigid 1966. Ka : Teleleht nr. 11, lk.4

Huvitavaid kohtulahendeid kindlustusasjades / Aare-Matti Inglist

Index Scriptorium Estoniae

Inglist, Aare-Matti

2007-01-01

Kindlustushüvitise määramisest tules hävinud elumaja ja koduse vara näitel (Riigikohtu lahendid 3-2-1-155-05 ja 3-21-1-155-06) ning lepinguvälise kahju hüvitamisest liiklusõnnetusjuhtumi näitel (Riigikohtu lahend 3-2-1-81-04)

Adaptive Aggregation Routing to Reduce Delay for Multi-Layer Wireless Sensor Networks.

Science.gov (United States)

Li, Xujing; Liu, Anfeng; Xie, Mande; Xiong, Neal N; Zeng, Zhiwen; Cai, Zhiping

2018-04-16

The quality of service (QoS) regarding delay, lifetime and reliability is the key to the application of wireless sensor networks (WSNs). Data aggregation is a method to effectively reduce the data transmission volume and improve the lifetime of a network. In the previous study, a common strategy required that data wait in the queue. When the length of the queue is greater than or equal to the predetermined aggregation threshold ( N t ) or the waiting time is equal to the aggregation timer ( T t ), data are forwarded at the expense of an increase in the delay. The primary contributions of the proposed Adaptive Aggregation Routing (AAR) scheme are the following: (a) the senders select the forwarding node dynamically according to the length of the data queue, which effectively reduces the delay. In the AAR scheme, the senders send data to the nodes with a long data queue. The advantages are that first, the nodes with a long data queue need a small amount of data to perform aggregation; therefore, the transmitted data can be fully utilized to make these nodes aggregate. Second, this scheme balances the aggregating and data sending load; thus, the lifetime increases. (b) An improved AAR scheme is proposed to improve the QoS. The aggregation deadline ( T t ) and the aggregation threshold ( N t ) are dynamically changed in the network. In WSNs, nodes far from the sink have residual energy because these nodes transmit less data than the other nodes. In the improved AAR scheme, the nodes far from the sink have a small value of T t and N t to reduce delay, and the nodes near the sink are set to a large value of T t and N t to reduce energy consumption. Thus, the end to end delay is reduced, a longer lifetime is achieved, and the residual energy is fully used. Simulation results demonstrate that compared with the previous scheme, the performance of the AAR scheme is improved. This scheme reduces the delay by 14.91%, improves the lifetime by 30.91%, and increases energy

Adaptive Aggregation Routing to Reduce Delay for Multi-Layer Wireless Sensor Networks

Directory of Open Access Journals (Sweden)

Xujing Li

2018-04-01

Full Text Available The quality of service (QoS regarding delay, lifetime and reliability is the key to the application of wireless sensor networks (WSNs. Data aggregation is a method to effectively reduce the data transmission volume and improve the lifetime of a network. In the previous study, a common strategy required that data wait in the queue. When the length of the queue is greater than or equal to the predetermined aggregation threshold ( N t or the waiting time is equal to the aggregation timer ( T t , data are forwarded at the expense of an increase in the delay. The primary contributions of the proposed Adaptive Aggregation Routing (AAR scheme are the following: (a the senders select the forwarding node dynamically according to the length of the data queue, which effectively reduces the delay. In the AAR scheme, the senders send data to the nodes with a long data queue. The advantages are that first, the nodes with a long data queue need a small amount of data to perform aggregation; therefore, the transmitted data can be fully utilized to make these nodes aggregate. Second, this scheme balances the aggregating and data sending load; thus, the lifetime increases. (b An improved AAR scheme is proposed to improve the QoS. The aggregation deadline ( T t and the aggregation threshold ( N t are dynamically changed in the network. In WSNs, nodes far from the sink have residual energy because these nodes transmit less data than the other nodes. In the improved AAR scheme, the nodes far from the sink have a small value of T t and N t to reduce delay, and the nodes near the sink are set to a large value of T t and N t to reduce energy consumption. Thus, the end to end delay is reduced, a longer lifetime is achieved, and the residual energy is fully used. Simulation results demonstrate that compared with the previous scheme, the performance of the AAR scheme is improved. This scheme reduces the delay by 14.91%, improves the lifetime by 30.91%, and increases

GPS navigation algorithms for Autonomous Airborne Refueling of Unmanned Air Vehicles

Science.gov (United States)

Khanafseh, Samer Mahmoud

Unmanned Air Vehicles (UAVs) have recently generated great interest because of their potential to perform hazardous missions without risking loss of life. If autonomous airborne refueling is possible for UAVs, mission range and endurance will be greatly enhanced. However, concerns about UAV-tanker proximity, dynamic mobility and safety demand that the relative navigation system meets stringent requirements on accuracy, integrity, and continuity. In response, this research focuses on developing high-performance GPS-based navigation architectures for Autonomous Airborne Refueling (AAR) of UAVs. The AAR mission is unique because of the potentially severe sky blockage introduced by the tanker. To address this issue, a high-fidelity dynamic sky blockage model was developed and experimentally validated. In addition, robust carrier phase differential GPS navigation algorithms were derived, including a new method for high-integrity reacquisition of carrier cycle ambiguities for recently-blocked satellites. In order to evaluate navigation performance, world-wide global availability and sensitivity covariance analyses were conducted. The new navigation algorithms were shown to be sufficient for turn-free scenarios, but improvement in performance was necessary to meet the difficult requirements for a general refueling mission with banked turns. Therefore, several innovative methods were pursued to enhance navigation performance. First, a new theoretical approach was developed to quantify the position-domain integrity risk in cycle ambiguity resolution problems. A mechanism to implement this method with partially-fixed cycle ambiguity vectors was derived, and it was used to define tight upper bounds on AAR navigation integrity risk. A second method, where a new algorithm for optimal fusion of measurements from multiple antennas was developed, was used to improve satellite coverage in poor visibility environments such as in AAR. Finally, methods for using data-link extracted

Salivary alpha amylase in on-call from home fire and emergency service personnel

Directory of Open Access Journals (Sweden)

Sarah J Hall

2017-10-01

Full Text Available The effect of working on-call from home on the sympatho-adrenal medullary system activity is currently unknown. This study had two aims, Aim 1: examine salivary alpha amylase awakening response (AAR and diurnal salivary alpha amylase (sAA profile in fire and emergency service workers who operate on-call from home following a night on-call with a call (NIGHT-CALL, a night on-call without a call (NO-CALL and an off-call night (OFF-CALL, and Aim 2: explore whether there was an anticipatory effect of working on-call from home (ON compared to when there was an off-call (OFF on the diurnal sAA profile. Participants wore activity monitors, completed sleep and work diaries and collected seven saliva samples a day for one week. AAR area under the curve with respect to ground (AUCG, AAR area under the curve with respect to increase (AUCI, AAR reactivity, diurnal sAA slope, diurnal sAA AUCG and mean 12-h sAA concentrations were calculated. Separate generalised estimating equation models were constructed for each variable of interest for each aim. For Aim 1, there were no differences between NIGHT-CALL or NO-CALL and OFF-CALL for any response variable. For Aim 2, there was no difference between any response variable of interest when ON the following night compared to when OFF the following night (n = 14. These findings suggest that there is no effect of working on-call from home on sAA, but should be interpreted with caution, as overnight data were not collected. Future research, using overnight heart rate monitoring, could help confirm these findings.

Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway.

Directory of Open Access Journals (Sweden)

Irina Gradinaru

Full Text Available α1a Adrenergic receptors (α1aARs are the predominant AR subtype in human vascular smooth muscle cells (SMCs. α1aARs in resistance vessels are crucial in the control of blood pressure, yet the impact of naturally occurring human α1aAR genetic variants in cardiovascular disorders remains poorly understood. To this end, we present novel findings demonstrating that 3D cultures of vascular SMCs expressing human α1aAR-247R (247R genetic variant demonstrate significantly increased SMC contractility compared with cells expressing the α1aAR-WT (WT receptor. Stable expression of 247R genetic variant also triggers MMP/EGFR-transactivation dependent serum- and agonist-independent (constitutive hyperproliferation and agonist-dependent hypertrophy of SMCs. Agonist stimulation reduces contractility Using pathway-specific inhibitors we determined that the observed hyperproliferation of 247R-expressing cells is triggered via β-arrestin1/Src/MMP-2/EGFR/ERK-dependent mechanism. MMP-2-specific siRNA inhibited 247R-triggered hyperproliferation indicating MMP-2 involvement in 247R-triggered hyperproliferation in SMCs. β-arrestin1-specific shRNA also inhibited 247R-triggered hyperproliferation but did not affect hypertrophy in 247R-expressing SMCs, indicating that agonist-dependent hypertrophy is independent of β-arrestin1. Our data reveal that in different cardiovascular cells the same human receptor genetic variant can activate alternative modulators of the same signaling pathway. Thus, our findings in SMCs demonstrate that depending on the type of cells expressing the same receptor (or receptor variant, different target-specific inhibitors could be used to modulate aberrant hyperproliferative or hypertrophic pathways in order to restore normal phenotype.

Alanyl-tRNA synthetase mutation in a family with dominant distal hereditary motor neuropathy

Science.gov (United States)

Zhao, Z.; Hashiguchi, A.; Sakiyama, Y.; Okamoto, Y.; Tokunaga, S.; Zhu, L.; Shen, H.; Takashima, H.

2012-01-01

Objective: To identify a new genetic cause of distal hereditary motor neuropathy (dHMN), which is also known as a variant of Charcot-Marie-Tooth disease (CMT), in a Chinese family. Methods: We investigated a Chinese family with dHMN clinically, electrophysiologically, and genetically. We screened for the mutations of 28 CMT or related pathogenic genes using an originally designed microarray resequencing DNA chip. Results: Investigation of the family history revealed an autosomal dominant transmission pattern. The clinical features of the family included mild weakness and wasting of the distal muscles of the lower limb and foot deformity, without clinical sensory involvement. Electrophysiologic studies revealed motor neuropathy. MRI of the lower limbs showed accentuated fatty infiltration of the gastrocnemius and vastus lateralis muscles. All 4 affected family members had a heterozygous missense mutation c.2677G>A (p.D893N) of alanyl-tRNA synthetase (AARS), which was not found in the 4 unaffected members and control subjects. Conclusion: An AARS mutation caused dHMN in a Chinese family. AARS mutations result in not only a CMT phenotype but also a dHMN phenotype. PMID:22573628

Kodanikud, võltsingud ja zombid / Tanel Tammet

Index Scriptorium Estoniae

Tammet, Tanel

2005-01-01

Autor avaldab arvamust, et e-valimiste vastu olevad erakonnad ja poliitikud pole mures mitte niivõrd nende valimiste turvalisuse pärast, vaid pigem seepärast, et e-valimised võivad suurendada noorema valijaskonna aktiivsust. E-valimiste õnnestumine võib viia mõttele Šveitsi otsedemokraatia mõne põhimõtte rakendamise kohta Eestis. Autor kirjeldab turvariske, mis võivad kaasneda e-valimistel

Mood, marss välja! / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Eesti moemärkide esindajad lähiajal välisturgude hõivamise soovist ja võimalusest. Andmeid kaubamärkide - Monton, Ivo Nikkolo, Bastion, Beself, Mithio, BonBon Lingerie, Xenia Joost, Tallinn Dolls - ning nende turgude ja disainerite kohta

Ilus elu kõige kiuste / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Disainist majanduslanguse ajal. Kodusest taaskasutusest. Rõivaste siluetist, materjalidest, aksessuaaridest. Vabrikupoodide võidukäigust. Moenädalate kammerlikuks muutumisest. Reet Ausi kaubamärki ReUse saab näha Londoni moenädala raames avataval näitusel

EXPO : hoiupõrsad ja triibud / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Shanghais toimuva EXPO 2010 Eesti paviljoni konkursi võitis töö "Savecity.org", mille autorid on Ionel Lehari, Kristian Paljasma (agentuur Identity), Illimar Truverk, Priit Hamer (Agabus, Endjärv & Truverk Arhitektid), Janno Roos, Andres Labi (Ruumilabor)

Võimsate isiksuste paraad New Yorgis / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2010-01-01

Marina Abramobići (Serbia) näitus "The Artist is Present" ja William Kentridge'i (Lõuna-Aafrika) söejoonistuste ja animatsioonide näitus "Five themes" MoMa-s (Museum of Modern Art). Tim Burtoni (USA) fotolavastuste, joonistuste ja installatsioonide näitus ning Agnolo Bronzino (1503-1572, Itaalia) joonistuste väljapanek Metropolitan Museumis

Terasniidist sündinud pesu / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2010-01-01

7. detsembril 70. sünnipäeva tähistavast pesuvabrikust "Linette". Ettevõte loodi 1940. aastal tootmisartelli "Võit" nime all. 37 aastat on ettevõtet juhtinud Mai Parras. Viimastel kümnenditel valmistatud naiste aluspesust, praegusest pesumoest

Vöökirjatud veetorn Võrumaal / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Lasva renoveeritud veetornist (renoveerimisprojekt: arhitekt Veronika Valk), kus asub Veetorni galerii, mille dominant on mitmel häälel helisev klavertrepp (teostus: skulptor Kalle Pruuden, Kalle Tikas). Seintel on fotograaf Peeter Lauritsa ja ajaloolase Uuno Ojala koostatud piirkonda tutvustav püsiväljapanek

Oksana Tandit ei tunnista kompromissi / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Ukraina juurtega moekunstnikust Oksana Tanditist, tema moeloomingust, kollektsioonist, mis on pühendatud väliseesti kunstniku Ruth Tulvingu maalitud liblikatele. 2007. a. detsembrist on Oksana Tandit ajakirja "Avenüü" peatoimetaja ja loovjuht

Keera korter päikesesse / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Itaalia arhitekti David Fisheri pöörleva pilvelõhkuja projektist. 80-korruseline moodulitest ökoelamu peaks valmina Dubais 2010. a. Iga korrus liigub teistest sõltumatult ja teeb 360-kraadise tiiru ühe tunniga

Mastaabi ja miniatuuri kahekõne / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2010-01-01

Metallikunstnik Urve Küttneri ja keraamik Annika Tederi näitus Viinistu Kunstimuuseumi tünnigaleriis 28. augustini 2010. Per Suntumi (Taani) ja Jaapani juurtega Kaori Juzu näitus Tallinnas A-Galeriis 16. augustini 2010

Viis värvikat visiooni / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Eesti Kunstiakadeema lõputööde näitus "Tase'09" Rüütelkonna hoones Toompeal 21. juunini. Arhitekt Martin Voltri Tartu linnujaama projektist. Madis Nurmsi lavakujundusest ja -kostüümidest Jules Massenet' ooperile "Thais", mis esietendus 22. mail Pärnu Endlas. Klaasikunstnik Merle Bukoveci sisepurskkaevude seeriast "Voolujooned". Tootedisainer Pent Talveti magistritööst. Uku-Kristjan Küttise tehtud kirjatüübist

Integrated Battlefield Effects Research for the National Training Center. Appendix E. Requirements Design Specification and Demonstration Report for the Exercise Coordination and Control (ECC) Demonstration System

Science.gov (United States)

1984-12-31

mode 3. Edit AAR mode 4. Run AR mode Each of the modes shall be mutually eclusive. In the real-time mode, the station tactical display shall reflect...periods of the exercise segment. The edit AAR mode shall provide the operator with the capability of creating/ editing a command file for use during an...II .,II IH 0 - hUi I -24 .6d, -I" @ 0 M% A A a a dJ a) 6 I I - -- a’ 1.* % 46- 8 ’ 0 "S 8 -- -- "- - I .-36 aISa "S-a:z:-a I I b 0 Il -- I -- I1 -I

An inexpensive underwater mine countermeasures simulator with real-time 3D after action review

Directory of Open Access Journals (Sweden)

Robert Stone

2016-10-01

Full Text Available This paper presents the results of a concept capability demonstration pilot study, the aim of which was to investigate how inexpensive gaming software and hardware technologies could be exploited in the development and evaluation of a simulator prototype for training Royal Navy mine clearance divers, specifically focusing on the detection and accurate reporting of the location and condition of underwater ordnance. The simulator was constructed using the Blender open source 3D modelling toolkit and game engine, and featured not only an interactive 3D editor for underwater scenario generation by instructors, but also a real-time, 3D After Action Review (AAR system for formative assessment and feedback. The simulated scenarios and AAR architecture were based on early human factors observations and briefings conducted at the UK's Defence Diving School (DDS, an organisation that provides basic military diving training for all Royal Navy and Army (Royal Engineers divers. An experimental pilot study was undertaken to determine whether or not basic navigational and mine detection components of diver performance could be improved as a result of exposing participants to the AAR system, delivered between simulated diving scenarios. The results suggest that the provision of AAR was accompanied by significant performance improvements in the positive identification of simulated underwater ordnance (in contrast to non-ordnance objects and on participants' description of their location, their immediate in-water or seabed context and their structural condition. Only marginal improvements were found with participants' navigational performance in terms of their deviation accuracies from a pre-programmed expert search path. Overall, this project contributes to the growing corpus of evidence supporting the development of simulators that demonstrate the value of exploiting open source gaming software and the significance of adopting established games design

Alkane biosynthesis genes in cyanobacteria and their transcriptional organization

Directory of Open Access Journals (Sweden)

Stephan eKlähn

2014-07-01

Full Text Available In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl-acyl carrier protein reductase (AAR and aldehyde deformylating oxygenase (ADO. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado and sll0209 (aar, that give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313 and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in

An approach regarding aging management program for concrete containment structure at the Gentilly-2 Nuclear Power Plant

Energy Technology Data Exchange (ETDEWEB)

Chenier, J-O.; Komljenovic, D., E-mail: Chenier.jean-olivier@hydro.qc.ca [Nuclear Power Plant Gentilly-2, Becancour, Quebec (Canada); Gocevski, V. [Hydro-Quebec Equipment, Structural Dept., Quebec (Canada); Picard, S.; Chretien, G. [Nuclear Power Plant Gentilly-2, Becancour, Quebec (Canada)

2012-07-01

The current paper presents the approach used by the Gentilly-2 Nuclear Power Plant, Hydro-Quebec, in elaborating a specific Aging Management Program (AMP) for its concrete containment structure. It is developed as a part of preparation activities for the plant refurbishment project. The specificity of the AMP consists in addressing Alkali-Aggregate Reaction (AAR) degradation mechanism which is not well known in the nuclear power industry. HQ developed a numerical model based on finite elements for assessing the concrete containment structure behaviour under the impact of AAR and other relevant degradation mechanisms. Such predictions enable a better targeting of corrective and mitigating actions during the second cycle of the G-2 operation while required. (author)

Noormees paneb Kanepi kooli tantsima / Milvi Hirvlaane

Index Scriptorium Estoniae

Hirvlaane, Milvi

2006-01-01

Tantsupedagoog Aare Laine tegevusest Kanepi gümnaasiumis, kus ta on lapsed esimesest kuni viimase klassini tantsima pannud. Tema viimaseid tantsuhitte "Chicken Power" teenis Koolitantsu finaalis eripreemia

Plasma Levels of Dimethylarginines in Preterm Very Low Birth Weight Neonates: Its Relation with Perinatal Factors and Short-Term Outcome

Directory of Open Access Journals (Sweden)

Rob M. Moonen

2014-12-01

Full Text Available Endogenously produced inhibitors of nitric oxide (NO synthase, in particular asymmetric dimethylarginine (ADMA, are currently considered of importance in various disease states characterized by reduced NO availability. We investigated the association between plasma levels of ADMA, symmetric dimethylarginine (SDMA, l-arginine, and citrulline and perinatal factors and outcome in 130 preterm (gestational age ≤30 weeks very low birth weight (VLBW, <1500 g infants. Plasma samples were collected 6–12 h after birth. We did not find significant correlations between ADMA, SDMA, l-arginine, and citrulline levels and gestational age or birth weight. However, the arginine:ADMA ratio (AAR, a better indicator of NO availability than either arginine or ADMA separately was positively correlated with gestational age. ADMA and arginine levels were not significantly different between males and females but males showed a negative correlation between ADMA levels and gestational age. Perinatal factors such as preeclampsia, chrorioamnionitis, prolonged rupture of membranes, or form of delivery did not significantly alter dimethylarginine levels or AAR. In contrast, the AAR was significantly reduced in the infants with respiratory distress, mechanical ventilation, and systemic hypotension Therefore, our data suggest that altered NO availability may play a role in the respiratory and cardiovascular adaptation in preterm VLBW infants.

Age estimation based on aspartic acid racemization in human sclera.

Science.gov (United States)

Klumb, Karolin; Matzenauer, Christian; Reckert, Alexandra; Lehmann, Klaus; Ritz-Timme, Stefanie

2016-01-01

Age estimation based on racemization of aspartic acid residues (AAR) in permanent proteins has been established in forensic medicine for years. While dentine is the tissue of choice for this molecular method of age estimation, teeth are not always available which leads to the need to identify other suitable tissues. We examined the suitability of total tissue samples of human sclera for the estimation of age at death. Sixty-five samples of scleral tissue were analyzed. The samples were hydrolyzed and after derivatization, the extent of aspartic acid racemization was determined by gas chromatography. The degree of AAR increased with age. In samples from younger individuals, the correlation of age and D-aspartic acid content was closer than in samples from older individuals. The age-dependent racemization in total tissue samples proves that permanent or at least long-living proteins are present in scleral tissue. The correlation of AAR in human sclera and age at death is close enough to serve as basis for age estimation. However, the precision of age estimation by this method is lower than that of age estimation based on the analysis of dentine which is due to molecular inhomogeneities of total tissue samples of sclera. Nevertheless, the approach may serve as a valuable alternative or addition in exceptional cases.

49 CFR 179.7 - Quality assurance program.

Science.gov (United States)

2010-10-01

... means to detect any nonconformity in the manufacturing, repair, inspection, testing, and qualification... nonconformities. (8) Provisions indicating that the requirements of the AAR Specifications for Tank Cars (IBR, see...

Saaremaa politseijuht pensionile / Andres Sepp

Index Scriptorium Estoniae

Sepp, Andres, 1976-

2005-01-01

Kuressaare politseijaoskonna ülemkomissar Ants Ley esitas politseiametile lahkumisavalduse. Väidetavalt on nimetatud ühe võimaliku politseijuhikandidaadina Lääne prefektuuri teenistusosakonna komissari Aare Alliku nime. Lisa: Ants Ley

Routine blood tests to predict liver fibrosis in chronic hepatitis C.

Science.gov (United States)

Hsieh, Yung-Yu; Tung, Shui-Yi; Lee, Kamfai; Wu, Cheng-Shyong; Wei, Kuo-Liang; Shen, Chien-Heng; Chang, Te-Sheng; Lin, Yi-Hsiung

2012-02-28

To verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C, compared with other noninvasive tests. This retrospective cohort study included 237 consecutive patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment. FibroQ, aspartate aminotransferase (AST)/alanine aminotransferase ratio (AAR), AST to platelet ratio index, cirrhosis discriminant score, age-platelet index (API), Pohl score, FIB-4 index, and Lok's model were calculated and compared. FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced (analysis of variance test: P fibrosis score in chronic hepatitis C compared with other noninvasive tests. FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C.

A 9,000-year-old caribou hunting structure beneath Lake Huron.

Science.gov (United States)

O'Shea, John M; Lemke, Ashley K; Sonnenburg, Elizabeth P; Reynolds, Robert G; Abbott, Brian D

2014-05-13

Some of the most pivotal questions in human history necessitate the investigation of archaeological sites that are now under water. Nine thousand years ago, the Alpena-Amberley Ridge (AAR) beneath modern Lake Huron was a dry land corridor that connected northeast Michigan to southern Ontario. The newly discovered Drop 45 Drive Lane is the most complex hunting structure found to date beneath the Great Lakes. The site and its associated artifacts provide unprecedented insight into the social and seasonal organization of prehistoric caribou hunting. When combined with environmental and simulation studies, it is suggested that distinctly different seasonal strategies were used by early hunters on the AAR, with autumn hunting being carried out by small groups, and spring hunts being conducted by larger groups of cooperating hunters.

Oral cancer statistics in India on the basis of first report of 29 population-based cancer registries

Science.gov (United States)

Sharma, Swati; Satyanarayana, L; Asthana, Smitha; Shivalingesh, KK; Goutham, Bala Subramanya; Ramachandra, Sujatha

2018-01-01

Objectives: To summarize and provide an overview of age-specific oral cancer incidence reported in 29 population-based cancer registry in India. Materials and Methods: Secondary data on age-adjusted rates (AARs) of incidence of oral cancer and other associated sites for all ages (0–75 years) were collected from the report of the National Cancer Registry Programme 2012–2014 in 29 population-based control registries. Results: Among both males and females, mouth cancer had maximum Age adjusted incidence rates (64.8) in the central zone, while oropharynx cancer had minimum AAR (0) in all regions. Conclusion: Oral cancer incidence increases with age with typical pattern of cancer of associated sites of oral cavity seen in the northeast region. PMID:29731552

Armastusest kahel ajajärgul / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2000-01-01

Mängufilm "Prantsuse leitnandi naine" ("The French Lieutenant's Woman") : stsenarist Harold Pinter John Fowles'i romaani järgi : režissöör Karel Reisz : Suurbritannia 1981. Ka : Nädal nr. 35, lk. 14

Pictures of fear and horror / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2009-01-01

Autor lapsena unes hirmu põhjustanud piltidest. Ants Laikmaa pastellmaalist "Marie Underi portree (1904), selle sarnasusest Edvard Munchi kujutatud naistega ("Angstgefühl", 1896). Jüri Arraku illustratsioonist "Vanapagan" lasteraamatule "Suur Tõll" (1982). Otsa vaatavatest portreedest (Leonardo da Vinci "Mona Lisa")

Avastamata aare - Soomaa / Merle Adams, Rait Parts

Index Scriptorium Estoniae

Adams, Merle

2009-01-01

Euroopa Komisjoni algatatud rahvusvahelisest projektist EDEN "European Tourist Destinations of Exellence" ning selle raames toimunud Euroopa kontekstis loodusturismi sihtkohtade konkursi "European Destinations of Exellence" Eesti 2009. aasta sihtkoha tiitli võitnud Soomaa rahvuspargist

Sõjas nagu sõjas ikka / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001. Lühidalt ka teistest ilmasõda kajastavatest seriaalidest

Karl Kello - elukutse olla saarlane / Aare Laine

Index Scriptorium Estoniae

Laine, Aare, 1951-

2004-01-01

Kuressaare Kuursaalis näidati kadripäeval nelja Ruta Celma ja Karl Kello kultuuriloolist dokumentaalfilmi : "Narr Jumala kojas" (2000), "Phaetonit otsides" (1999), "Eestlased Lätis" (2004) ja Kalevipoja temaatikat arendav "Küll siis Kalev..." (2004). Filmide operaator on Arvo Vilu. Artikli autor kõneleb Karl Kellost, tema Karja kiriku ja Kaali järve problemaatika arendustest peale filmide ka kirjasõnas

Veemajandus saab jõudsalt areneda / Aare Lepaste

Index Scriptorium Estoniae

Lepaste, Aare, 1970-

2004-01-01

8. detsembril kirjutasid seitsme vee-ettevõtte esindajad, KIK-i juhataja ja keskkonnaminister alla Eesti suurimale keskkonnaprojektile. Projekti eesmärk on viia omavalitsuste veemajanduse infrastruktuur vastavusse EL-i direktiividega.

Kivisildnik versus Under : lausuvad subjektid / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2016-01-01

Sven Kivisildniku tekstidest, eriti "Märg Viktor" ja seal leiduvast intertekstuaalsusest. Artikli aluseks on 18.-19. apr. 1997 Otepääl TÜ ja TPÜ kirjandustudengite ja -magistrantide konverentsil 'Vaade sillalt' peetud ettekanne

Halvad, halvemad ja äravalitud / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2003-01-01

Ameerika Filmiinstituudi küsitluse järgi on maailma kõigi aegade kõige meeldejäävamaks kurjuse kehastuseks kinolinal Hannibal Lecter mängufilmides "Voonakeste vaikimine", "Hannibal" ja "Punane draakon" Anthony Hopkinsi kehastuses. Kõige sümpaatsemaks positiivseks tegelaseks valiti Atticus Finch draamas "Tappa laulurästast" Gregory Pecki kehastuses

Perekonnaportree interjööris / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2005-01-01

Lühiseriaal Mannide kirjanikedünastia saatusest 1930-1940-ndail aastail "Mannide perekond" ("Die Manns") : stsenaristid Heinrich Breloer ja Horst Königstein : režissöör Heinrich Breloer : Saksamaa 2001

India rentslimiljonär tegi ilma ka Oscarite peol / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2009-01-01

2008.a. filmiloomingu kaheksa Oscarit sai Danny Boyle'i mängufilm "Rentslimiljonär" ("Slumdog Millionaire"), produtsent Christian Colson. Lisatud Aare Tilga ja Timo Dieneri kommentaarid ning peamiste Oscarite nimekiri

"Миллионер из трущоб" покорил США / Тийт Туумалу

Index Scriptorium Estoniae

Туумалу, Тийт

2009-01-01

2008.a. filmiloomingu kaheksa Oscarit sai Danny Boyle'i mängufilm "Rentslimiljonär" ("Slumdog Millionaire"), produtsent Christian Colson. Lisatud Aare Tilga ja Timo Dieneri kommentaarid ning peamiste Oscarite nimekiri

Kohtumine küünlasäras. Dave Benton annab 12 jõulukontserti

Index Scriptorium Estoniae

2005-01-01

Tõnu Raadiku ja Aare Jaama kontserdist "Lumevarjude vahel" 11. dets. Pärnu Raekoja saalis. Uue albumi "Generations" üllitanud Dave Bentoni ja gospelkooride kontsertidest Eesti kirikutes (9. dets. Pärnu Eliisabeti kirikus)

Kehanarratiivid / Gregory Slick ; tõlk. Mari Laaniste

Index Scriptorium Estoniae

Slick, Gregory

2003-01-01

Reio Aare, Toomas Kalve, Margot Kase, Herkki-Erich Merila fotonäitus "The Fragments of Silence: Meditative moments in contemporary Estonian photography" 10.-26. IV New Yorgi galeriis Annex. Kuraator Rael Artel

Eestlased vigu parandamas ehk väikevormidest suurvormini, disainist reekviemini / Märt Kubo

Index Scriptorium Estoniae

Kubo, Märt, 1944-

2007-01-01

Eesti Kultuurfilmis valminud Juhan Aare (produtsent, autor) dokumentaalfilm NSVL rahvasaadikute kongressil 1989-1991 tegutsenud Eesti saadikute tegevusest ja iseseisvuse eest võitlemisest "Eestlased Kremlis" (režissöör Toomas Lepp)

Baltic cooperation vs Visegrad cooperation (essay) / Tanel Sepp

Index Scriptorium Estoniae

Sepp, Tanel

2004-01-01

Baltimaade ning Visegrad grupi riikide (Poola, Ungari, Tšehhi, Slovakkia) arengust NSV Liidu mõjusfääris olevatest piirkondadest iseseisvateks riikideks, koostööst Euroopa Liidu ja NATO kontekstis

Narva-Jõesuu semmib Hispaania veekeskuste ehitajaga / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2006-01-01

Narva-Jõesuu linnavalitsus plaanib ühel linna omanduses olevatest kruntidest alustada aktiivset veekeskuse arendust, partneriks ligi 40-aastase kogemusega Hispaania firma "Action Park Multiforma Grupo S.L."

Eesti transpordi infrastruktuuri ootavad suured toetused / Tanel Tang

Index Scriptorium Estoniae

Tang, Tanel

2003-01-01

EL-iga liitumisel avanevad Eestile Euroopa Regionaalarengu fond (ERDF) ja Ühtekuuluvusfond, mis tähendab transpordisektorile miljardite kroonide suurust abi maanteede, raudteede, lennujaamade ning sadamate ehitamiseks ja rekonstrueerimiseks. Vt. samas: Eestile tulnud abi PHARE ja ISPA fondist ; Ühtekuuluvusfond ja Euroopa regionaalarengu fond (ERDF) toetavad Eestit miljonite kroonidega. Diagramm: EL-i abi Eesti transpordisektorile

Narva osales turismimesil Leningradi oblasti boksis / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Ilmunud ka: Narva Postiljon 26. jaan. lk. 1. Narva linnavalitsuse turismispetsialist Katrin Liblik põhjendab, miks osales Narva Helsingis toimunud turismimessil "Matka 2008" Leningradi oblasti boksis

Pinocchio, Capone ja teised klaasist kangelased / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Näitus "Kaasaegne Slovakkia klaasikunst" Eesti Tarbekunsti- ja Disainimuuseumis" 10. aprillini 2011, kuraator Zora Petrášová. Václav Cigleri mõjust slovaki klaasikunsti arengusse, Patrik Illo, Miloš Balgavy, Ján Zoričaki ja Palo Macho töödest

Matrix, skynet ja sõda teispoolsusega / Tanel Tammet

Index Scriptorium Estoniae

Tammet, Tanel

2003-01-01

Oletusest, et kiirenev tehnoloogia areng viib kvalitatiivse murranguni, mis pöörab senise elukorralduse pea peale. Kuid siiski, miks peaksid masintsivilisatsioonid tahtma inimesi orjastada või hävitada?

"Schmuck": klassika mäss ehtes / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Ehtekunsti suurüritusest "Schmuckszene" Münchenis. Hollandi kunstiajaloolase Marjan Ungeri koostatud peanäitusest, millel osales tekstiilikunstnik Marta Kisand Eestist. Satelliitnäitustest: itaalia ehtekunstnike väljapanekust, Karl Fritschi, Gerd Rothmanni (Saksamaa) ja Robert Bainesi (Austraalia) näitusest, väljapanekust "Auf Vorrat", retrospektiivist Dorothea Prühli (Poola) loomingust

Meelis Virkebau : Kreenholm peaks meediaga suhtlema / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2007-01-01

Ilmunud ka: Narva Postiljon, 5. apr. 2007, lk. 1,2; Narvskaja Gazeta, 5. apr. 2007, lk. 1,2. Kreenholmi endine juht Meelis Virkebau ei mõista Narva linnapea Tarmo Tammiste seisukohta, et 3000 töötut ei ole linnale probleem, samuti peab ta mõtlematuks peaminister Andrus Ansipi väidet, et Kreenholmi probleem pole nii hull kui paistab. M. Virkebau selgitab oma lahkumist ettevõtte juhi kohalt 2003. aastal

Matti Haarajoki : ma ei ole likvidaator / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2007-01-01

Ilmunud ka: Narva Postiljon, 5. apr. 2007, lk. 1,2; Narvskaja Gazeta, 5. apr. 2007, lk. 1,2. Kreenholmi tegevjuht lükkab ümber väite, nagu kavatsetaks Kreenholm sulgeda. Järgmiseks aastaks vähendatakse töötajate arvu ettevõttes umbes 800 inimese võrra. Sotsiaalminister Jaak Aab ja rahvastikuminister Paul-Eerik Rummo vastavad küsimusele, kas Kreenholmi kriis võib ajendada Ida-Virumaal sotsiaalse plahvatuse. Lisa: Ajalugu

Lennart Meri lennujaamas tunned end koduselt / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Tallinna lennujaama reisiterminali laiendusest. Eskiislahendused on loonud Jean-Marie Bonnard Prantsuse firmast Sofreavia SA. Põhiosa arhitektuursest lahendusest koostas Inge Põder arhitektuuri- ja projekteerimisbüroost EA Reng AS

Thoracic lymph node station recognition on CT images based on automatic anatomy recognition with an optimal parent strategy

Science.gov (United States)

Xu, Guoping; Udupa, Jayaram K.; Tong, Yubing; Cao, Hanqiang; Odhner, Dewey; Torigian, Drew A.; Wu, Xingyu

2018-03-01

Currently, there are many papers that have been published on the detection and segmentation of lymph nodes from medical images. However, it is still a challenging problem owing to low contrast with surrounding soft tissues and the variations of lymph node size and shape on computed tomography (CT) images. This is particularly very difficult on low-dose CT of PET/CT acquisitions. In this study, we utilize our previous automatic anatomy recognition (AAR) framework to recognize the thoracic-lymph node stations defined by the International Association for the Study of Lung Cancer (IASLC) lymph node map. The lymph node stations themselves are viewed as anatomic objects and are localized by using a one-shot method in the AAR framework. Two strategies have been taken in this paper for integration into AAR framework. The first is to combine some lymph node stations into composite lymph node stations according to their geometrical nearness. The other is to find the optimal parent (organ or union of organs) as an anchor for each lymph node station based on the recognition error and thereby find an overall optimal hierarchy to arrange anchor organs and lymph node stations. Based on 28 contrast-enhanced thoracic CT image data sets for model building, 12 independent data sets for testing, our results show that thoracic lymph node stations can be localized within 2-3 voxels compared to the ground truth.

2007. aasta raamatute tipp-10 / Kadri Kõusaar

Index Scriptorium Estoniae

Kõusaar, Kadri, 1980-

2007-01-01

Ilukirjandusest: Dovlatov, Sergei. Leivatöö. Võõramaa naine; Pilv, Aare. Näoline; Tsvetajeva, Marina. Elu tules : pihtimused; Kaplinski, Jaan. Seesama jõgi; García Márquez, Gabriel. Elada, et sellest jutustada

Interesting coin finds of 2005 / Mauri Kiudsoo

Index Scriptorium Estoniae

Kiudsoo, Mauri, 1973-

2006-01-01

2005. aasta arheoloogilistel kaevamistel avastatud müntidest väärivad eraldi märkimist nn. traatkopikad. Kõige rohkem traatkopikaid leiti Vastseliina piiskopilinnuselt. Üks traatkopikatest koosnenud aare leiti Koruste külast

Lugedes Pilve ja Pazi / Mathura

Index Scriptorium Estoniae

Mathura, pseud., 1973-

2007-01-01

Võrdlevalt Aare Pilve luulekogust "Näoline" (kirj. Tuum, 2007) ja Octavio Pazi luulekogust "Alati on olevik" (hispaania k. tlk. Ain Kaalep, Jaan Kaplinski, Asta Põldmäe ja Jüri Talvet, kirj. Perioodika, 1984)

Influence of mesostasis in volcanic rocks on the alkali-aggregate reaction

KAUST Repository

Tiecher, Francieli

2012-11-01

Mesostasis material present in the interstices of volcanic rocks is the main cause of the alkali-aggregate reaction (AAR) in concretes made with these rock aggregates. Mesostasis often is referred to as volcanic glass, because it has amorphous features when analyzed by optical microscopy. However, this study demonstrates that mesostasis in the interstitials of volcanic rocks most often consists of micro to cryptocrystalline mineral phases of quartz, feldspars, and clays. Mesostasis has been identified as having different characteristics, and, thus, this new characterization calls for a re-evaluation of their influence on the reactivity of the volcanic rocks. The main purpose of this study is to correlate the characteristics of mesostasis with the AAR in mortar bars containing basalts and rhyolites. © 2012 Elsevier Ltd. All rights reserved.

Influence of mesostasis in volcanic rocks on the alkali-aggregate reaction

KAUST Repository

Tiecher, Francieli; Dal Molin, Denise Carpena Coitinho; Gomes, Má rcia Elisa Boscato; Hasparyk, Nicole Pagan; Monteiro, Paulo José Meleragno

2012-01-01

Mesostasis material present in the interstices of volcanic rocks is the main cause of the alkali-aggregate reaction (AAR) in concretes made with these rock aggregates. Mesostasis often is referred to as volcanic glass, because it has amorphous features when analyzed by optical microscopy. However, this study demonstrates that mesostasis in the interstitials of volcanic rocks most often consists of micro to cryptocrystalline mineral phases of quartz, feldspars, and clays. Mesostasis has been identified as having different characteristics, and, thus, this new characterization calls for a re-evaluation of their influence on the reactivity of the volcanic rocks. The main purpose of this study is to correlate the characteristics of mesostasis with the AAR in mortar bars containing basalts and rhyolites. © 2012 Elsevier Ltd. All rights reserved.

Hidden State Conditional Random Field for Abnormal Activity Recognition in Smart Homes

Directory of Open Access Journals (Sweden)

Yu Tong

2015-03-01

Full Text Available As the number of elderly people has increased worldwide, there has been a surge of research into assistive technologies to provide them with better care by recognizing their normal and abnormal activities. However, existing abnormal activity recognition (AAR algorithms rarely consider sub-activity relations when recognizing abnormal activities. This paper presents an application of the Hidden State Conditional Random Field (HCRF method to detect and assess abnormal activities that often occur in elderly persons’ homes. Based on HCRF, this paper designs two AAR algorithms, and validates them by comparing them with a feature vector distance based algorithm in two experiments. The results demonstrate that the proposed algorithms favorably outperform the competitor, especially when abnormal activities have same sensor type and sensor number as normal activities.

Kalvi mõisas algas Seitsme Linna muusikafestival / Ago Gashkov

Index Scriptorium Estoniae

Gashkov, Ago

2004-01-01

Festivalist Seitsme Linna Muusika 18.-25. juulini (kunstiline juht Aare Tammesalu) Kalvi mõisas, Narva Aleksandri kirikus, Lüganuse kirikus, Kohtla-Järve Linnagaleriis, Sillamäel, Narva-Jõesuu Valges pargis ja Jõhvi Mihkli kirikus

Muusikalised maiuspalad raekojas

Index Scriptorium Estoniae

2009-01-01

26. juulil Pärnu raekojas toimuvast kontserdist "Grande Serenade", esitusel Johann Hummeli serenaadid (Grande Serenade), esinevad Arvo Leibur (viiul), Heiki Mätlik (kitarr), Madis Kari (klarnet), Aare Tammesalu (tšello) ja Tarmo Eespere (klaver)

Kriisikoldeid kustutab (teatri)mäng / Rait Avestik

Index Scriptorium Estoniae

Avestik, Rait, 1974-

2010-01-01

Itaallaste Nino d’Introna ja Giacomo Ravicchio teksti põhjal valminud seiklusloost „Robinson & Crusoe”, tõlkinud Kirke Org, lavastanud Aare Toikka. Esietendus 27. nov. 2009 VAT-teatris. Mängivad Meelis Põdersoo ja Ago Soots

EAS vahendas mullu Harjumaale 47 miljonit krooni toetusi / Allar Korjas

Index Scriptorium Estoniae

Korjas, Allar

2005-01-01

Möödunud aastal jõudis EAS- i vahendusel alustavate ja tegutsevate ettevõtete ning regionaalse arengu toetamiseks Harjumaale 47,1 miljonit krooni. Tabel. Vt. samas: Aare Ets. Regionaalne koostöö Harjumaal on oluline

Kruuda, Vichmann ja Kilp kavandavad Rocca al Maresse tervisemetropoli / Raigo Neudorf

Index Scriptorium Estoniae

Neudorf, Raigo

2007-01-01

Rocca al Mare Suurhalli uued omanikud Aare Kilp, Marcel Vichmann ja Oliver Kruuda plaanivad suurhalli lähedusse rajada suure ja uuelaadse vabaaja- ja spordikeskuse. Vt. samas: Kasumisse jõudmist takistab laenukoorem; Külastajate arv kasvab

"Rudi" polutshil glavnõi priz

Index Scriptorium Estoniae

2006-01-01

Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

Grand prix / J. U.

Index Scriptorium Estoniae

J. U.

2006-01-01

Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

"Ruudi" võitis Tokyos

Index Scriptorium Estoniae

2006-01-01

Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

ORF Alignment: NC_002939 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available NC_002939 gi|39996821 >1v7zA 3 252 1 232 3e-42 ... ref|NP_952772.1| creatinine amidoh...ydrolase [Geobacter sulfurreducens PCA] ... gb|AAR35099.1| creatinine amidohydrolase [Geobacter ...

"Ruudi" - helge muinasjutt lastele, iroonia vanematele / Teelemari Loonet

Index Scriptorium Estoniae

Loonet, Teelemari, 1987-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : operaator Rein Kotov : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006

Adding an Intelligent Tutoring System to an Existing Training Simulation

National Research Council Canada - National Science Library

Stottler, Richard H; Jensen, Randy; Pike, Bill; Bingham, Rick

2006-01-01

...). It was determined that the addition of an Intelligent Tutoring System (ITS) to BC2010 would off-load the instructor from these duties and allow the students to execute scenarios without requiring an instructor for the AAR...

Reval Hotel Lietuva Vilniuses : Konstitucijos pr. 20 / Piret Lindpere

Index Scriptorium Estoniae

Lindpere, Piret, 1963-

2004-01-01

Vilniuse hotelli "Lietuva" renoveerimine. Arhitektuurse projekti koostaja Rootsi arhitektuuribüroo AB SWECO (arhitektid Aare Saks, Nils Palm. Sisekujundus: Vaikla Disain AS (Katrin ja Argo Vaikla, Liis Lindvere, Peeter Loo). Kommenteerivad Argo ja Katrin Vaikla. 3 ill

Perception of Community Health Extension Services among Women ...

African Journals Online (AJOL)

UNIBEN

communities were: Sentu, Ile-Apa, Budo-. Aare, Alalubosa ... community for at least six months in order to be used to the ... edition (SPSS-18). Data were ..... Manual for Governments and Other ... gazette. Legal Notice on Publication of.

NCBI nr-aa BLAST: CBRC-MDOM-02-0463 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MDOM-02-0463 ref|NP_954911.1| large tegument protein [Bovine herpesvirus 5] gb...|AAR86125.1| UL36 very large tegument protein [Bovine herpesvirus 5] NP_954911.1 8e-11 34% ...

Self-Assessment Based Mini-After Action Review (SAMAAR) Methodology: Developmental Application to Division Artillery Staff Training

National Research Council Canada - National Science Library

Mirabella, Angelo

1998-01-01

.... In the SAMAAR approach, trainees, at the end of an exercise day or shift fill out rating forms to assess the units training progress and then convene with their completed forms to participate in a mini-AAR...

Durability and acoustics of concrete with slag of cupola furnace as fine aggregate replacement

Directory of Open Access Journals (Sweden)

Ricardo Alfredo Cruz Hernández

2015-01-01

Full Text Available In this paper, it was evaluated the performance of concrete with crushed slag of cupola furnace (SCF as sand replacement in percentages of 0 %, 10 %, 15 % and 20 %, subjected to accelerated chemical attacks of carbonation, sulfation and alkali-aggregate reaction (AAR. The sound absorption characteristics of the material were determined through the sound absorption coefficient (α, and the noise reduction coefficient (NRC. Carbonation was evaluated through a closed camera with the 70 % concentration of carbon dioxide and conditions of relative humidity between 50 % and 70 %. The results indicated that the penetration depth of CO2 is lower when greater the percentage of substitution is. To accelerate the attack by sulfates, specimens were immersed in aqueous solution of sodium sulfate anhydrous (Na2SO4 1N with cycles of wetting and drying. It determined that the impairment presented in concrete paste is directly proportional to the percentage of sand replacement. The acceleration of the AAR in the concrete was carried out by immersing specimens in an aqueous solution of sodium hydroxide (NaOH for 16 days. The test concluded that the inclusion of SCF is not favorable for AAR. The measurement of sound absorption coefficient was taken by the method of impedance tube, relating minimum and maximum values of stationary wave amplitude. The results showed that SCF with higher sand replacement are favorable for the noise absorption in buildings.

Kivirähk korraga kahel laval / Tiiu Laks

Index Scriptorium Estoniae

Laks, Tiiu, 1984-

2009-01-01

31. jaan. Ugalas esietenduvast Andrus Kivirähki esimesest näidendist "Vanamehed seitsmendalt" Peeter Tammearu lavastuses ja VAT Teatris lavale jõudvast Kivirähki uusimast tükist "Ingel, ingel, vii mind taeva" Aare Toikka lavastuses

Homo soveticusest eesti inimeseni / Mart Niklus

Index Scriptorium Estoniae

Niklus, Mart-Olav, 1934-

2004-01-01

Autori mõtisklused Eesti lipust, antikommunistlikust vastupanuliikumisest nõukogude ajal, Nõukogude okupatsiooni käsitlevatest muuseumidest. Sisaldab artiklit "Rahvuslipp "Vanemuise" katusel ja Aare Printsi kohtuasi", allikas : Lisandusi mõtete ja uudiste vabale levikule Eestis. I kogu. Stockholm, 1984

ORF Alignment: NC_002128 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available ing protein SopA [Large-insert cloning vector ... pSMART VC] gb|AAR05665.1| stabilization of plasmid ... ... protein A [Salmonella typhimurium] gb|AAO61293.1| ParA ... [BAC cloning vector pEBAC190G

Süütust näpates : Tanel Veenre fotoseeria teatrikostüümidest Draamateatri laval / Tanel Veenre, Hanna Tiidus, Margit Soosaar...[jt.

Index Scriptorium Estoniae

2007-01-01

Stilist: Hanna Tiidus. Naine: Merle Palmiste. Poiss: Joonas (MJ-Models). Kostüümid etendustest "Rohuvoodi" (Aime Unt), "Rehepapp", "Tõeline inspektor koer" (Ene-Liis Semper), "Liilia" (Lilja Blumenfeld), "Mort" (Kersti Varrak), "Potilaadale" (Reet Aus), "Amadeus" (Krista Tool)

ORF Alignment: NC_003075 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available NC_003075 gi|30692533 >3ullA 5 115 1 104 8e-18 ... ref|YP_063478.1| ssb1 [Campylobact...er jejuni] gb|AAR29567.1| ssb1 [Campylobacter ... jejuni] ... Length = 104 ... Query: 31 ... GQDSDVS

Composite Monopack for 120mm Mortar, With Plastic Pallet Adapters on a 42" x 53" Wooden Pallet, MIL-STD-1660 Tests, "Design Criteria for Ammunition Unit Loads", and Extreme Temperature Tests

National Research Council Canada - National Science Library

Dugan, Jeffery L

2005-01-01

... (AMSRD-AAR-AIL-P) to conduct MIL-STD-1660 Tests to determine if the composite monopack for the 120MM mortar, with plastic pallet adapters on a 42" x 53" wooden pallet, designed by US Army ARDEC and manufactured...

Lilleküla jalgpallistaadion = Lilleküla Football Stadium / Haldo Oravas

Index Scriptorium Estoniae

Oravas, Haldo, 1960-

2001-01-01

Arhitekt, projekti ja detailplaneeringu (AS Eesti Projekt, 1999) autor Haldo Oravas. Projekteerijad: ETP Grupp, projektijuht Aare Uusalu, arhitekt Peep Urb. Sisekujundaja Sirje Pohl. Projekt 2000-2001. 8 ill.: V korruse ja asendiplaan, tribüüni lõige, vaated

Kuidas lugeda "Meeste domineerimist"? / Patrick Champagne ; tlk. Marek Tamm

Index Scriptorium Estoniae

Champagne, Patrick

2005-01-01

Rets. rmt.: Bourdieu, Pierre. Meeste domineerimine. Tallinn, 2005. Kommenteerivad (lk. 12-14) Liina Lukas, Rein Ruutsoo (TLÜ õppejõud), Marina Grišakova, Aare Pilv, Airi-Alina Allaste, Raivo Vetik (TLÜ Õppejõud), Andres Härm, Voldemar Tomusk

Riigikokku pääseb läbi kolme sõela / Marko Suurmägi

Index Scriptorium Estoniae

Suurmägi, Marko, 1975-

2007-01-01

Kui iga erakonna üleriigilise nimekirja järjestus jääb samaks ka pärast valimisi, siis piirkondlik reastatakse pärast tulemuste selgumist saadud häälte arvu järgi ümber. Nii kerkib iga partei kõige rohkem hääli saanud liige esimeseks ja vähim toetust leidnud kandidaat viimaseks. Lisa: Võimalused. Isamaa ja Res Publica Liidu kandidaadi Helir-Valdor Seedri ja Rahvaliidu kandidaadi Jaak Alliku arvamus. Vt. samas lühiinter. valimistel osalevate erakondade esindajate Priit Toobali (Keskerakond), Meelis Atoneni (Reformierakond), Jaak Alliku (Rahvaliit), Helir-Valdor Seedri (Isamaa ja Res Publica Liit), Heiki Järveveeri (Sotsiaaldemokraatlik Erakond), Tanel Tammeti (Erakond Eestimaa Rohelised) ja Valentine Alvrega (Eesti Kristlikud Demokraadid)

Narva linnuse arhitektuurivõistlus ja selle ülesanne / Toomas Paaver

Index Scriptorium Estoniae

Paaver, Toomas, 1976-

2015-01-01

SA Narva Muuseum korraldas arhitektuurivõistluse, et leida terviklik ruumiline lahendus Narva linnuse hoonete ja territooriumi ümberehituseks. Esimese koha sai töö märgusõnaga "Kaks sõpra" (Kalle Vellevoog, Tiiu Truus, Lidia Zarudnaja ja Martin Prommik arhitektuuribüroost JVR). Teise koha sai töö märgusõnaga "Ulm" (Jaan Kuusemets, Üllar Ambos, Pille Noole, Kaisa Lasner ja Ionnais Lykouras arhitektuuribüroost DAGOpen ja LÜNK Arhitektid"). Kolmanda koha sai töö märgusõnaga "Aedificium" (Ott Kadarik, Mihkel Tüür, Kristi Tuurmann, Kadri Tamme, Marleen Stokkeby, Viktoria Andrejeva, Constantin Rybkin ja Tanel Trepp arhitektuuribüroost KTA - Kadarik Tüür Arhitektid)

Pal-tänava poisid" võitis Peterburis kõrge auhinna

Index Scriptorium Estoniae

2006-01-01

VAT Teater osales 4.-10. maini Peterburis VII rahvusvahelisel noorsooteatrite festivalil "Vikerkaar" lavastusega "Pál-tänava poisid" (autor Ferenc Molnár, lavastaja Aare Toikka) ja pälvis ühe peapreemiatest : auhinna parimale näitlejate ansamblile

Dosje festivalei : "Raduga". 4-10 maja 2006 g. Tjuz im. A. Brjantseva / Jelena Gorfunkel

Index Scriptorium Estoniae

Gorfunkel, Jelena

2006-01-01

4.-10. maini Peterburis toimunud VII rahvusvahelisest noorsooteatrite festivalist "Vikerkaar". Arvustatakse ka VAT Teatri lavastust "Pál-tänava poisid" (autor Ferenc Molnár, lavastaja Aare Toikka). Pälvis ühe peapreemiatest : auhinna parimale näitlejate ansamblile

Adept at adapting : contributions of sociology to agricultural research for small farmers in developing countries : in case of rice in the Dominican Republic

NARCIS (Netherlands)

Doorman, F.

1991-01-01

This book discusses possible contributions of sociology and anthropology to agricultural research. It is based on investigations carried out from 1981 to 1985 in the Dominican Republic in the Adaptive Agricultural Research (AAR) project, a cooperative effort between the Agricultural

LACK OF EFFECT OF AGE AND ANTIOXIDANT DEPLETION ON RESPIRATORY RESPONSES TO CONCENTRATED AMBIENT PARTICULATES (CAPS) IN RATS

Science.gov (United States)

2003 AAR PM MeetingParticulate Matter: Atmospheric Sciences,Exposure and the Fourth Colloquium on PM and Human HealthLACK OF EFFECT OF AGE AND ANTIOXIDANT DEPLETION ON RESPIRATORY RESPONSES TO CONCENTRATED AMBIENT PARTICULATES (CAPs) IN RATS. JA Dye, LC Walsh, C...

Glavnõi Oskar - "Stolknoveniju" / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2006-01-01

Kuidas ja miks juhtus, et 78. Ameerika Filmiakadeemia Oscari-tseremoonial kuulutati parimaks filmiks Paul Haggise "Kokkupõrge" ("Crash") seni üldiselt favoriidiks peetud Ang Lee "Brokebacki mäe" ("Brokeback Mountain") asemel. Lisatud arvamused, mille autoriteks Aare Tilk ja Ilmar Raag

Vene telesarjad sõnaga Sirbis (VII) / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Kümnejaolisest telepõnevikust "Kooljate teater" ("Teatr obretshjonnõh"), stsenaristid T. Artseulova ja A. Suvorova, Mihhail Marti romaani motiividel, režissöör A. Parhomenko (MakDos/Iljuzionfilmz 2006). Võrdlus Rainer Sarneti "Libahundi needusega"

Tantsijast poksipoiss, aristokraadid ja hulluõde / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2000-01-01

IV Pimedate Ööde Filmifestivalil linastunud mängufilmidest : Suurbritannia "Billy Elliot" : režissöör Stephen Daldry, Ungari-Austria-Kanada "Päikesepaiste" ("Sunshine") : režissöör István Szab̤ ja Saksamaa "Keisrinna ja sõjamees" ("Der Krieger und die Keiserin") : režissöör Tom Tykwer

Irooniline pilguheit Iirima lähiajaloole / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

Mängufilm "Väike lihunik" ("The Butcher Boy") : Stsenaristid Neil Jordan ja Patrick McCabe viimase samanimelise romaani järgi : režissöör Neil Jordan : Ameerika Ühendriigid 1997. Ka : Teleleht nr. 1, lk. 4

San Sebastiani festivali varjutasid hiljutised terroriaktid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

San Sebastiani rahvusvahelisel filmifestivalil sai Suure Kuldse merikarbi tšiillase Orlando Lubberti film "Takso kolmele". Parima režissööri auhinna pälvis Jean-Pierre Ameris realistliku draamaga "C'est la vie". Ka teistest auhinnatutest

Meri on mereriigi majanduskasvu eeldus / Aare-Maldus Uustalu

Index Scriptorium Estoniae

Uustalu, Aare-Maldus, 1935-

2005-01-01

Eesti majanduskasvu edukus merenduse ja siseveetranspordi arendamise valdkonnas sõltub mitte üksnes teadlaste panusest, vaid suurel määral riigiametnike töö kvaliteedist, nende suutlikkusest ja vastutustundest, leiab autor. Tabelid. Kaart

Molecular evidence of fungal signatures in the marine protist Corallochytrium limacisporum and its implications in the evolution of animals and fungi

Digital Repository Service at National Institute of Oceanography (India)

Manohar, C; Raghukumar, S.; Kasbekar, D.P.; Raghukumar, C

and ergosterol, in one of the isolates. These features, as well as the sterol C-14 reductase gene involved in the sterol pathway of animals and fungi were detected in the organism. Phylogenetic trees based on the α-AAR gene suggested that Corallochytrium...

ORF Alignment: NC_003070 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available NC_003070 gi|18397761 >1wocC 2 96 2 97 5e-15 ... ref|YP_063428.1| ssb1 [Campylobacter... ... gb|EAL55921.1| single-strand binding protein, putative ... [Campylobacter coli RM2228] gb|AAR29517.1| ssb1

Ruudi läheb Tokyosse / Olev Remsu

Index Scriptorium Estoniae

Remsu, Olev, 1947-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : operaator Rein Kotov : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006. Lähemalt analüüsitakse stsenaariumi

Sellest, mis teiste eest varjatud / Rainer Sarnet

Index Scriptorium Estoniae

Sarnet, Rainer, 1969-

2000-01-01

USA mängufilmid "Tabamatu ilu" (American Beauty") : režissöör Sam Mendes : 1999 ja "Õnn" ("Happiness") : režissöör Todd Solondz : 1998. Lisa : Aare Ermeli koostatud režissööride lühielulood

Oscarite peost sai Marty triumf / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2007-01-01

Oscarite võitjad põhikategooriates. Suurim võitja oli Martin Scorsese oma filmiga "Kahe tule vahel" ("The Departed") - parim film, parim režissöör, parim stsenaarium, parim montaazh. Kommenteerivad Aare Tilk ja Timo Diener. Lisatud nimekiri "Oscari võitjad"

Cardiovascular magnetic resonance imaging of myocardial oedema following acute myocardial infarction

DEFF Research Database (Denmark)

Hamshere, Stephen; Jones, A Daniel; Pellaton, Cyril

2016-01-01

patients after successful primary percutaneous coronary intervention. 82 patients underwent a novel 3-slice SAX protocol and 85 patients underwent standard 10-slice SAX protocol. AAR was obtained by manual endocardial and epicardial contour mapping followed by a semi- automated selection of normal...

Külaline kunstiilma tipust / Mark Jones ; intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Jones, Mark

2010-01-01

Kumu Kunstimuuseumis on 23. jaanuarini 2011 avatud näitus "John Constable. Victoria & Alberti muuseumi kogudest". Tallinnas viibinud muuseumi direktori söör Mark Jonesiga John Costable'i loomingust, Tallinna näitusest, Constable'i kollektsioonist Victoria & Alberti muuseumis, Victoria & Alberti muuseumist ja selle näitustest

Ehe : patt või püha? / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2003-01-01

Muljeid ehtekunstinäituselt "Palve. Puudutus. Patt" Tallinna Kunstihoone galeriis. Rein Metsa, Arseni Mölderi, Kristi Saare, Bruno Lillemetsa, Kärt Marani, Lilian Linnaksi, Kaie Partsi ja Adolfas Shaulyse töödest

21. sajandi mammut / Martin Rästa ; intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Rästa, Martin, 1980-

2010-01-01

Kujundusgraafik Martin Rästaga (Mammut) tema tööst, loomingust, trendidest, graafilise disaini näituse eesmärkidest jm. Martin Rästa plakatite näitus "MMMT10" Tartu Y-galeriis 29. märtsist 10. aprillini 2010

Investor goda narushajet stroitelnõje zakonõ / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2004-01-01

Narva hotell-restorani "King" ebaseaduslikust ümberehitamisest. Projekti koostajad on OÜ Narva ehitusprojekti projekteerijad Tatjana Zhuravljova ja Olga Medvedjeva. Linnaarhitekti kohusetäitja Anne Halliku kommentaare

Ai Weiwei - 21. sajandi märter? / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Hiina kunstniku, inimõiguslase ja teisitimõtleja Ai Weiwei elust, õpingutest, loomingust ja tegevusest. Hiinas kunstniku tagakiusamisest, arreteerimisest, maksupettuses süüdistamisest jm. Kunstniku toetajatest. Inglise kunstileht Art Review valis Ai Weiwei 2011. a. kõige mõjuvõimsamaks kunstitegelaseks

Kapo vahistas pistise pakkumise kahtlusega Narva linnavoliniku / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Ilmunud ka: Narva Postiljon 30. aug. lk. 1. Kaitsepolitsei pidas 28.augustil altkäemaksu andmises kahtlustatavana kinni Narva linnavolikogu liikme, keskerakondlase Aleksandr Moissejevi. Vahistamise asjaolusid kaitsepolitsei ei kommenteeri. Lisa: Äripartner hämmastunud

Poola ja Venemaa leppimine elavdab Narva seatransiiti / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Elussigade vedu Narva kaudu Venemaale võib tänu Poola ja Venemaa vahel saavutatud kokkuleppele suureneda. Maksu- ja tolliameti Narva büroo juhi Jevgeni Budalovi väitel moodustavad elussead marginaalselt väikese osa Narvas piiri ületava kauba väärtusest

Pilet mustvalgesse paradiisi ehk sügismood / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

2009. a. juuli alguses toimunud kõrgmoe nädalast Pariisis. Giorgio Armani, Karl Lagerfeldi (Chanel), Christian Lacroix', John Galliano (Dior), Riccardo Tisci (Givenchy) ja Jean Paul Gaultier' kollektsioonidest

Värviline disain punase mõtte kiuste / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2012-01-01

Näitused: "Me metamorfne tulevik. Disain, tehniline esteetika ja eksperimentaalne arhitektuur Nõukogude Liidus 1960-1980" ja "Moderniseerimine. Balti kunst, arhitektuur ja disain 1960.-1970. aastatel"

Maarit Murka: oluline on olla igav / intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Murka, Maarit, 1981-

2011-01-01

Maalikunstnik Maarit Murka endast, oma loomingust, endise NSV Liidu vabariikides 2010. a. toimunud isikunäitustest, pikemalt näituse avamisest Minskis, rännakutest maailma pühapaikadesse jm. 2009. aastast õpib M. Murka Balti Filmi- ja Meediakooli stsenaristika magistrantuuris

Ürgjõuga köidetud Tormised / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2010-01-01

Rahvusvaheline köitekunsti näitus-konkurss "Scripta manent IV" Eesti Tarbekunsti- ja Disainimuuseumis 9. jaanuarini 2011. Väljas on 171 köidet 22 riigist. Kunstnikud köitsid Veljo Tormise "Lauldud sõna"

Päästa enda sisemine hunt valla! / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Ameerika 2008.a. mängufilmist "Mässajate tänav" ("Revolutionary Road"), stsenarist Richard Yates'i samanimelise raamatu järgi Justin Haythe, režissöör Sam Mendes, peaosades Kate Winslet, Leonardo DiCaprio

President vabastas Jüri Sakkarti kohtuniku ametist / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2010-01-01

President Toomas Hendrik Ilves kirjutas 9. veebruaril 2010 alla otsusele vabastada Jüri Sakkart Viru Maakohtu kohtuniku ametist tema enda soovil. Kaitsepolitsei on J. Sakkarti kuriteokahtlustusega kinni pidanud

Konksu otsas graafiline disainer Jan Tomson / intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Tomson, Jan

2009-01-01

Jan Tomson endast, oma loomingust, rulasõidust, muusikategemisest, ajakirjast "Sahtel", igapäevadisainist jm. Jan Tomson on teinud plakateid, plaadikujundusi, logosid, grafitit, disaininud Kumu täpilise bussi ja optilise mustriga trammi ning muud

Tsenõ na morskije perevozki poleteli vniz / Tanel Raig

Index Scriptorium Estoniae

Raig, Tanel, 1975-

2008-01-01

Puistekaupade meretranspordi hinnaindeks Baltic Dry Index (BDI) on mai lõpust langenud 13 korda ja jõudnud 2002. aasta alguse tasemele. Vt. samas: Stoimost morskihh perevozok v blizhaisheje vremja rasti ne budet

Prostate cell membrane chromatography-liquid chromatography-mass spectrometry for screening of active constituents from Uncaria rhynchophylla.

Science.gov (United States)

He, Jianyu; Han, Shengli; Yang, Fangfang; Zhou, Nan; Wang, Sicen

2013-01-01

Uncaria rhynchophylla is a traditional Chinese medicinal herb used to treat hypertension and convulsive disorders such as epilepsy. Rat prostate cell membrane chromatography combined with liquid chromatography-mass spectrometry (LC-MS) was used to identify active constituents from U. rhynchophylla extracts. Four compounds (corynoxeine, isorhynchophylline, isocorynoxeine and rhynchophylline) were discovered. Competitive binding assay results indicated that the four compounds were in direct competition at a single common binding site and interacted with α1A adrenergic receptors (α1A-AR) in a manner similar to tamsulosin. Affinity constant values of the four compounds binding with α1A-AR were also measured using rat prostate cell membrane chromatography (CMC). Finally, their pharmacodynamic effects were tested on rat caudal arteries. This CMC combined LC-MS system offers a means of drug discovery by screening natural medicinal herbs for new pharmacologically active molecules targeting specific receptors.

An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity

Directory of Open Access Journals (Sweden)

Ju Youn Beak, PhD

2017-02-01

Full Text Available Summary: Alpha-1 adrenergic receptors (α1-ARs play adaptive and protective roles in the heart. Dabuzalgron is an oral selective α1A-AR agonist that was well tolerated in multiple clinical trials of treatment for urinary incontinence, but has never been used to treat heart disease in humans or animal models. In this study, the authors administered dabuzalgron to mice treated with doxorubicin (DOX, a widely used chemotherapeutic agent with dose-limiting cardiotoxicity that can lead to heart failure (HF. Dabuzalgron protected against DOX-induced cardiotoxicity, likely by preserving mitochondrial function. These results suggest that activating cardiac α1A-ARs with dabuzalgron, a well-tolerated oral agent, might represent a novel approach to treating HF. Key Words: alpha adrenergic receptors, anthracyclines, cardioprotection, catecholamines, heart failure

Kuidas kommenteerite hoolekogu rolli enda koolis? / Mihkel Rebane, Margus Leek, Hannes Astok ... [jt.

Index Scriptorium Estoniae

2011-01-01

Küsimusele vastavad Kiili gümnaasiumi direktor Mihkel Rebane, Mart Reiniku gümnaasiumi hoolekogu vilistlaste esindaja Margus Leek, riigikogulane, HTG hoolekogu liige Hannes Astok, Puurmani gümnaasium õpilasesinduse president Kertu Vahtra ja Saku gümnaasiumi hoolekogu esimees Aare Järvelaid

Eesti sumokamp ja esijudoka videolindil / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

1999-01-01

Dokumentaalfilmid maadlejatest : "Legend päikesest" : stsenarist, režissöör, toimetaja ja produtsent Aare Tilk : Eesti Telefilm 1999 ja "Tempo di valse" : käsikiri Hans Roosipuu ja Peeter Simm : režissöör Peeter Simm : Faama Film 1999

Personal Epistemology of Urban Elementary School Teachers

Science.gov (United States)

Pearrow, Melissa; Sanchez, William

2008-01-01

Personal epistemology, originating from social construction theory, provides a framework for researchers to understand how individuals view their world. The Attitudes About Reality (AAR) scale is one survey method that qualitatively assesses personal epistemology along the logical positivist and social constructionist continuum; however, the…

Kolm tähelepanuväärset bibliograafiat / Tiina Ritson

Index Scriptorium Estoniae

Ritson, Tiina, 1955-

2011-01-01

Arvustus: Uku Masing 100 : bibliograafia 1923-2009 / koost. Anneli Sepp. Tartu : Ilmamaa, 2010. Voldemar Panso bibliograafia / koost. Katre Riisalu, Eha Garšnek, Mari Sibul. Tallinn : Eesti Draamateater, 2010. Pilv, Aare. Juhan Viidingu ja Jüri Üdi bibliograafia // Juhan Viiding, eesti luuletaja. Tartu, 2010.

78 FR 54952 - Petition for Waiver of Compliance

Science.gov (United States)

2013-09-06

... improve safety and eliminate unnecessary costs to the industry. Through a limited pilot effort AAR intends... safe braking performance. The focus of this pilot will be the normal revenue service coal trains... through Friday, except Federal Holidays. Interested parties are invited to participate in these...

Armastust otsivad inimesed / Kristiina Davidjants

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2001-01-01

Paul Thomas Andersonist ja tema mängufilmidest "Kibe käsi" ("Hard Eight"), "Magnoolia" ("Magnolia") ja "Boogie Nights" : Ameerika Ühendriigid vastavalt 1996, 1999 ja 1997. Lisa : Aare Ermeli esitatud lühiandmed P. T. Andersoni kohta. Kokkuvõte inglise keeles lk. 96

Eesti lastefilm räägib üksikutest lastest ja üksikutest vanematest / Jürgen Rooste, Marko Martinson

Index Scriptorium Estoniae

Rooste, Jürgen, 1979-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : produtsent Piret Tibbo-Hudgins : operaator Rein Kotov : kunstnik Toomas Hõrak : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006

77 FR 76169 - Quarterly Rail Cost Adjustment Factor

Science.gov (United States)

2012-12-26

....stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public Assistance...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the AAR's proposed rebasing calculations and...

The South African Defence Force and Horse Mounted Infantry ...

African Journals Online (AJOL)

Jacques

2003-03-26

Mar 26, 2003 ... ranger and tracker in the Etosha National park after being offered the ... had a personal interest in the SADF horse stud farm at De Aar, and was a .... prudent to know the location of 'shonas'48, local wells and watering holes ...

Teater

Index Scriptorium Estoniae

2006-01-01

Vanemuise teatri draamanäitlejad tunnistasid möödunud aasta parimaks lavastuseks augustis Setumaal Obinitsas etendunud "Taarka", mille lavastas Ain Mäeots. Parimaks naispeaosatäitjaks valiti Merle Jääger, parimaks meespeaosatäitjaks Indrek Taalmaa, parimaks naiskõrvalosatäitjaks Karin Tammaru, parimaks meeskõrvalosatäitjaks Tanel Jonas. Eesti Draamateatri 2005. aasta Antsud ehk kolleegipreemiate laureaadid : Ingomar Vihmar (parim lavastaja), Ervin Õunapuu (parim kunstnik), Ülle Kaljuste (parim naisnäitleja), Ain Lutsepp (parim meesnäitleja), Väikesed Antsud pälvisid Elina Reinold ja Taavi Teplenkov, Abi-Antsuks kuulutati teatri kirjandusala juhataja Ene Paaver. Endla 2005. aasta kolleegipreemiad said Lii Tedre (parim naisnäitleja), Tambet Seling (parim meesnäitleja), Tiit Palu (parim lavastaja) ja Silver Vahtre (parim kunstnik)

76 FR 18073 - Track Safety Standards; Concrete Crossties

Science.gov (United States)

2011-04-01

... decomposition. FRA continues to believe that breaks, cracking, mechanical abrasion, or chemical reaction in... engineering performance, but was uneconomical. \\1\\ J.W. Weber, ``Concrete crossties in the United States... investigation,'' AAR, Engineering research division, Report No. ER-20 November 1961; and G.M. Magee and E. J...

75 FR 75963 - Export Trade Certificate of Review

Science.gov (United States)

2010-12-07

... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-9A001] Export Trade... Industries Association of America (``AIA'') (Application 92-9A001). SUMMARY: The U.S. Department of Commerce...: Accenture is now located in Chicago, IL, with controlling entity Accenture plc, Dublin, Ireland; AAR...

78 FR 5767 - Positive Train Control Systems (RRR)

Science.gov (United States)

2013-01-28

..., modify the default procedures for handling the en route failure of PTC systems, and allow automatic... seeks information sufficient to make a reasoned determination that benefits justify costs and therefore... practicability of the waiver process as an acceptable method of handling such operations. In the Petition, AAR...

77 FR 21311 - Locomotive Safety Standards

Science.gov (United States)

2012-04-09

... preparedness, alcohol and drug testing, locomotive engineer certification, and workplace safety. In 1980, FRA... Association (ATDA) Amtrak AAR Association of Railway Museums (ARM) Association of State Rail Safety Managers... Administration 49 CFR Parts 229 and 238 Locomotive Safety Standards; Final Rule #0;#0;Federal Register / Vol. 77...

49 CFR 171.7 - Reference material.

Science.gov (United States)

2010-10-01

.../publications.com; AAR Manual of Standards and Recommended Practices, Section C—Part III, Specifications for... Edition, March 1996 172.102. American Pyrotechnics Association (APA), P.O. Box 30438, Bethesda, MD 20824, (301) 907-8181, www.americanpyro.com: APA Standard 87-1, Standard for Construction and Approval for...

Journal of Child and Adolescent Mental Health - Vol 24, No 1 (2012)

African Journals Online (AJOL)

The theory of planned behaviour as a framework for predicting sexual risk behaviour in sub-Saharan African youth: A critical review · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Cleo Protogerou, Alan J Flisher, Leif Edvard Aarø, Catherine Mathews.

VAT teatril kaks uut noortelavastust / Tiiu Talvist

Index Scriptorium Estoniae

Talvist, Tiiu

2010-01-01

VAT teater panustab sel hooajal uutesse laste- ja noortelavastustesse: lisaks itaallaste Nino d’Introna ja Giacomo Ravicchio teksti põhjal valminud seiklusloole „Robinson & Crusoe” (lavastaja Aare Toikka), esietendub aprillis Mare Sabolotny noorte probleemidest kõnelev lavalugu „Kirjaklambritest vöö”. Lavastaja Rein Agur

Deklaratsioon = Declaration / Jaan Sõrra

Index Scriptorium Estoniae

Sõrra, Jaan, 1954-

2006-01-01

Konverentsi "580 päeva Euroopa Liidus " osalejate pöördumine. Vt ka vastused deklaratsioonile lk. 103-107 riigisekretär Heiki Loot, põllumajandusminister Ester Tuiksoo, haridus- ja teadusminister Mailis Reps, keskkonnaminister Villu Reiljan, Riigikogu kultuurikomisjon Olav Aarna, rahandusminister Aivar Sõerd ja Aare Järvan

Ärimehed tõid kuu ja päikese Narva-Jõesuusse

Index Scriptorium Estoniae

2009-01-01

2008. a. avatud Meresuu spaa-hotellist, mis ehitati nõukogudeaegse lõpetamata rajatise peale. Arhitektuurse lahenduse autor Andres Põime ja sisekujunduse autor Reet Põime arhitektuuribüroost Studio 3. Wellness-korruse sisekujundaja Liisi Murula. Purskkaevud-lillepeenrad kavandas Kersti Lootus. Omanikud: Aare Kööp, Rene Kuulmann

Application of a novel method for age estimation of a baleen whale and a porpoise

DEFF Research Database (Denmark)

Nielsen, Nynne H.; Garde, Eva; Heide-Jørgensen, Mads Peter

2013-01-01

Eyeballs from 121 fin whales (Balaenoptera physalus) and 83 harbor porpoises (Phocoena phocoena) were used for age estimation using the aspartic acid racemization (AAR) technique. The racemization rate (kAsp) for fin whales was established from 15 fetuses (age 0) and 15 adult whales where age...

Distinction of salvaged and infarcted myocardium within the ischaemic area-at-risk with T2 mapping

DEFF Research Database (Denmark)

Hammer-Hansen, Sophia; Ugander, Martin; Hsu, Li-Yueh

2014-01-01

values from T2 maps and signal intensities on T2-weighted images were measured in the corresponding areas. RESULTS: At both imaging time points, the T2 of the salvaged myocardium was longer than of remote (66.0 ± 6.9 vs. 51.4 ± 3.5 ms, P ...AIM: Area-at-risk (AAR) measurements often rely on T2-weighted images, but subtle differences in T2 may be overlooked with this method. To determine the differences in oedema between salvaged and infarcted myocardium, we performed quantitative T2 mapping of the AAR. We also aimed to determine...... (14.7 ± 5.6 vs. 8.7 ± 5.1 ms, P = 0.02). CONCLUSIONS: T2 relaxation parameters are different in the infarcted and salvaged myocardium, and both are significantly longer than remote. Furthermore, the magnitude of increase in T2 was less in the salvaged myocardium after longer reperfusion, indicating...

Direct dating of human fossils.

Science.gov (United States)

Grün, Rainer

2006-01-01

The methods that can be used for the direct dating of human remains comprise of radiocarbon, U-series, electron spin resonance (ESR), and amino acid racemization (AAR). This review gives an introduction to these methods in the context of dating human bones and teeth. Recent advances in ultrafiltration techniques have expanded the dating range of radiocarbon. It now seems feasible to reliably date bones up to 55,000 years. New developments in laser ablation mass spectrometry permit the in situ analysis of U-series isotopes, thus providing a rapid and virtually non-destructive dating method back to about 300,000 years. This is of particular importance when used in conjunction with non-destructive ESR analysis. New approaches in AAR analysis may lead to a renaissance of this method. The potential and present limitations of these direct dating techniques are discussed for sites relevant to the reconstruction of modern human evolution, including Florisbad, Border Cave, Tabun, Skhul, Qafzeh, Vindija, Banyoles, and Lake Mungo. (c) 2006 Wiley-Liss, Inc.

Indicação da anuscopia de alta resolução e citologia anal na prevenção de HPV e câncer colorretal em pacientes portadores de HIV Indication of high resolution anoscopy and anal cytology for prevention of HPV and colorectal cancer in HIV patients

Directory of Open Access Journals (Sweden)

Hugo Leonardo Madeiro Arcanjo Silva

2010-12-01

Full Text Available OBJETIVO: Rastreamento do papilomavírus humano (HPV assim como sua correlação com a neoplasia anorretal nos pacientes portadores do vírus da imunodeficiência humana (HIV por meio da anuscopia de alta resolução (AAR e da citologia anal. MÉTODOS: Desenvolvemos um estudo observacional, transversal e duplo-cego em que participaram 31 pacientes portadores do HIV independente de queixas proctológicas. Os pacientes foram submetidos à AAR e citologia anal cujas lâminas foram enviadas ao setor de anatomia patológica para coloração e posterior análise. RESULTADOS: Verificamos 22 pacientes do sexo masculino e 9 do sexo feminino entre 20 e 67 anos. Dos 31 analisados, quatro encontravam-se em estágio de imunodepressão, 23 utilizavam terapia antirretroviral, 16 com passado de sexo anal receptivo e 12 com passado de condiloma acuminado. À AAR 11 pacientes tinham alterações e 7 foram confirmados pela citologia. Verificamos ainda oito pacientes com alterações à citologia os quais possuíam ausência de alterações à AAR. À citologia apresentaram três células escamosas atípicas de significância (Ascus, do inglês atypical squamous cells of undetermined significance, cinco com paraceratose e/ou hiperceratose, seis lesões intraepiteliais de baixo grau e uma lesão intraepitelial de alto grau. CONCLUSÃO: Sugerimos a utilização da AAR aliada à citologia anal para rastreamento nos pacientes portadores do HIV, visto que esses exames complementam-se para a detecção de lesões que estejam relacionadas ao câncer anorretal.OBJECTIVE: Screening for HPV as well as its correlation with anorectal cancer in patients carrying the human immuno deficiency virus (HIV through high-resolution anoscopy (HRA and anal cytology. METHODS: We developed an observational study, double-blind attended by 31 patients with HIV independent proctologic complaints. Patients underwent HRA and anal cytology slides were sent to which sector pathology staining and

Novel Synergistic Therapy for Metastatic Breast Cancer: Magnetic Nanoparticle Hyperthermia of the Neovasculature Enhanced by a Vascular Disruption Agent

Science.gov (United States)

2013-04-01

bovine serum and antibiotics (VEC Technologies) on gelatin coated surface. SK- 0V-3 ovarian adenocarcinoma cell line was cultured at 37° C under a...are formed from mouse cells. Unlike xenograft models, which require an immunocompromised mouse to avoid rejection of the tumor, the PyMT mouse

Toward a Unified Military Response: Hurricane Sandy and the Dual Status Commander

Science.gov (United States)

2015-04-01

18th tropical depression of the season formed over the southwestern Caribbean Sea and quickly strength- ened into Tropical Storm Sandy late that... Centennial , a combined Title 10 and 32 operation, during the Sep- tember 2013 response to the Colorado Floods. 117 APPENDIX I ACRONYMS AAR After Action

Raadioteatri looming juubelieelsel aastal / Madis Kolk

Index Scriptorium Estoniae

Kolk, Madis, 1974-

2008-01-01

Raadioteatris 2007. aastal välja tulnud kuuest uuest kuuldemängust: Roland Schimmelpfennigi "Araabia öö", Aleksander Alleni "Elu sees", Aare Toikka viieosaline järjelugu "Kroonu", Mart Kivastiku "Nokia", Eva Östergreni "Tüdrukud", Üllar ja Rünno Saaremäe viieosaline lastelugu "Käpipuu vennaskond"

78 FR 7857 - Proposed Agency Information Collection Activities; Comment Request

Science.gov (United States)

2013-02-04

... below have been forwarded to the Office of Management and Budget (OMB) for review and comment. The ICRs... brand identification of the material. (3) Each individual unit of a glazing material that has...) the manufacturer of the material; (iii) the type or brand identification of the material. AAR believes...

Unit 1A: General Approach to the Teaching of Architecture

DEFF Research Database (Denmark)

Gammelgaard Nielsen, Anders

2011-01-01

An ideal course Ever since the founding of the Aar- hus School of Architecture in 1965 there has been a tradition for lively discussion surrounding the content of the architecture program. The discussion has often been con- ducted from ideological or norma- tive positions, with the tendency to st...

Proteomic-coupled-network analysis of T877A-androgen receptor interactomes can predict clinical prostate cancer outcomes between White (non-Hispanic and African-American groups.

Directory of Open Access Journals (Sweden)

Naif Zaman

Full Text Available The androgen receptor (AR remains an important contributor to the neoplastic evolution of prostate cancer (CaP. CaP progression is linked to several somatic AR mutational changes that endow upon the AR dramatic gain-of-function properties. One of the most common somatic mutations identified is Thr877-to-Ala (T877A, located in the ligand-binding domain, that results in a receptor capable of promiscuous binding and activation by a variety of steroid hormones and ligands including estrogens, progestins, glucocorticoids, and several anti-androgens. In an attempt to further define somatic mutated AR gain-of-function properties, as a consequence of its promiscuous ligand binding, we undertook a proteomic/network analysis approach to characterize the protein interactome of the mutant T877A-AR in LNCaP cells under eight different ligand-specific treatments (dihydrotestosterone, mibolerone, R1881, testosterone, estradiol, progesterone, dexamethasone, and cyproterone acetate. In extending the analysis of our multi-ligand complexes of the mutant T877A-AR we observed significant enrichment of specific complexes between normal and primary prostatic tumors, which were furthermore correlated with known clinical outcomes. Further analysis of certain mutant T877A-AR complexes showed specific population preferences distinguishing primary prostatic disease between white (non-Hispanic vs. African-American males. Moreover, these cancer-related AR-protein complexes demonstrated predictive survival outcomes specific to CaP, and not for breast, lung, lymphoma or medulloblastoma cancers. Our study, by coupling data generated by our proteomics to network analysis of clinical samples, has helped to define real and novel biological pathways in complicated gain-of-function AR complex systems.

Study of the density of ganglion cells in the terminal bowel of rats with anorectal malformations Estudo da densidade das células ganglionares no intestino terminal de ratos portadores de anomalia anorretal

Directory of Open Access Journals (Sweden)

Maurício Macedo

2007-12-01

Full Text Available PURPOSE: To study the ganglion cells (GC in the terminal bowel of rats with ethylenethiourea (ETU induced anorectal malformations (ARM. METHODS: The animals were divided into three groups: Group A - normal fetuses from pregnant rats that were not administered ETU; Group B - fetuses without ARM born from pregnant rats that were administered ETU and Group C - fetuses with ARM born from pregnant rats that received ETU. ETU was administered on the 11th day of pregnancy at the dose of 125 mg/kg body weight by gastric gavage. The rats had cesarean section on the 21st day of gestation. The fetuses’ terminal bowel tissue was analyzed by immunohistochemistry to demonstrate ganglion cells. RESULTS: Statistically significant differences were found between groups A, B and C regarding ganglion cell densities. Group A had the highest cell density, followed by Group B and the lowest density was found in Group C. CONCLUSION: Ganglion cell densities are decreased in the terminal bowel of rats with ARM.OBJETIVO: Estudar as células ganglionares (CG no intestino terminal de ratos portadores de anomalia anorretal (AAR induzida pela etilenotiouréia (ETU. MÉTODOS: Os animais foram distribuídos em três grupos: Grupo A - fetos normais, obtidos de ratas grávidas às quais não foi administrada ETU; Grupo B - fetos não portadores de AAR obtidos de ratas grávidas às quais foi administrada ETU e Grupo C - fetos portadores de AAR obtidos de ratas grávidas às quais foi administrada ETU. A ETU foi administrada no décimo primeiro dia de gestação na dose de 125 mg/Kg, por gavagem. As ratas foram submetidas à laparotomia e histerotomia para retirada dos fetos no vigésimo primeiro dia de gestação. O intestino terminal dos fetos foi retirado e analisado por imunohistoquímica para pesquisa de CG. RESULTADOS: Foram encontradas diferenças estatisticamente significantes entre os grupos A, B e C quanto à densidade de CG. O grupo A apresentou a maior densidade

Quantification of both the area-at-risk and acute myocardial infarct size in ST-segment elevation myocardial infarction using T1-mapping.

Science.gov (United States)

Bulluck, Heerajnarain; Hammond-Haley, Matthew; Fontana, Marianna; Knight, Daniel S; Sirker, Alex; Herrey, Anna S; Manisty, Charlotte; Kellman, Peter; Moon, James C; Hausenloy, Derek J

2017-08-01

A comprehensive cardiovascular magnetic resonance (CMR) in reperfused ST-segment myocardial infarction (STEMI) patients can be challenging to perform and can be time-consuming. We aimed to investigate whether native T1-mapping can accurately delineate the edema-based area-at-risk (AAR) and post-contrast T1-mapping and synthetic late gadolinium (LGE) images can quantify MI size at 1.5 T. Conventional LGE imaging and T2-mapping could then be omitted, thereby shortening the scan duration. Twenty-eight STEMI patients underwent a CMR scan at 1.5 T, 3 ± 1 days following primary percutaneous coronary intervention. The AAR was quantified using both native T1 and T2-mapping. MI size was quantified using conventional LGE, post-contrast T1-mapping and synthetic magnitude-reconstructed inversion recovery (MagIR) LGE and synthetic phase-sensitive inversion recovery (PSIR) LGE, derived from the post-contrast T1 maps. Native T1-mapping performed as well as T2-mapping in delineating the AAR (41.6 ± 11.9% of the left ventricle [% LV] versus 41.7 ± 12.2% LV, P = 0.72; R 2 0.97; ICC 0.986 (0.969-0.993); bias -0.1 ± 4.2% LV). There were excellent correlation and inter-method agreement with no bias, between MI size by conventional LGE, synthetic MagIR LGE (bias 0.2 ± 2.2%LV, P = 0.35), synthetic PSIR LGE (bias 0.4 ± 2.2% LV, P = 0.060) and post-contrast T1-mapping (bias 0.3 ± 1.8% LV, P = 0.10). The mean scan duration was 58 ± 4 min. Not performing T2 mapping (6 ± 1 min) and conventional LGE (10 ± 1 min) would shorten the CMR study by 15-20 min. T1-mapping can accurately quantify both the edema-based AAR (using native T1 maps) and acute MI size (using post-contrast T1 maps) in STEMI patients without major cardiovascular risk factors. This approach would shorten the duration of a comprehensive CMR study without significantly compromising on data acquisition and would obviate the need to perform T2 maps and LGE imaging.

49 CFR 232.603 - Design, interoperability, and configuration management requirements.

Science.gov (United States)

2010-10-01

... Specification,” Version 2.0 (Adopted: 1999; Revised: 2002); (4) AAR S-4230, “Intratrain Communication (ITC) Specification for Cable-Based Freight Train Control System,” Version 3.0 (Adopted: 1999; Revised: 2002, 2004..., “Performance Requirements for ITC Controlled Cable-Based Distributed Power Systems,” Version 2.0 (Adopted: 2003...

78 FR 48765 - Petition for Waiver of Compliance

Science.gov (United States)

2013-08-09

... Canada who participate as non-voting members. The Task Force drafted a base safety appliance standard for... that the AAR standard provides an equal or greater level of safety in each instance. In addition, the... parties are invited to participate in these proceedings by submitting written views, data, or comments...

49 CFR 179.4 - Changes in specifications for tank cars.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Changes in specifications for tank cars. 179.4... TANK CARS Introduction, Approvals and Reports § 179.4 Changes in specifications for tank cars. (a...—Tank Car Safety, AAR, for consideration by its Tank Car Committee. An application for construction of...

Pink läks pikemaks... / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

20. sept. VAT Teatris esietendunud Eesti Muusika ja Teatriakadeemia Lavakunstikooli lavastajate õppesuuna tudengite koolitööst "Pink", mis koosneb kahest iseseisvast loost - Jon Fosse "Talv", lavastaja Robert Annus ja Edward Albee "Loomaaialugu", lavastaja Uku Uusberg. Lisaks küsimus "Aare Toikka, kuidas noored lavastajatudengid VAT Teatri tiiva alla sattusid?"

76 FR 43662 - 36(b)(1) Arms Sales Notification

Science.gov (United States)

2011-07-21

... DEPARTMENT OF DEFENSE Office of the Secretary [Transmittal Nos. 11-15] 36(b)(1) Arms Sales... Department of Defense is publishing the unclassified text of a section 36(b)(1) arms sales notification. This...) Military Department: Navy (AAR) (v) Prior Related Cases, if any: None (vi) Sales Commission, Fee, etc...

Eesti võimalused Soome lahe kasvukolmnurgas / Aare-Maldus Uustalu

Index Scriptorium Estoniae

Uustalu, Aare-Maldus, 1935-

2005-01-01

Euroopa Komisjoni ekspert logistika, transpordi ja regionaalökonoomika alal, TTÜ Tallinna Kolledzhi dotsent 2002. aasta alguses käivitatud Soome lahe kasvukolmnurga projektist, Eesti majanduse arenguperspektiivist projekti raames ning Eesti riigiametnike ükskõiksusest projekti suhtes. Via Baltica lisakoridoride projekti Via Islands ideest

Masendav pilguheit Ida-Saksamaa lähiajaloole / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

10. PÖFFi filme: Sakslase Florian Henkel von Donnersmarcki debüütlavastus, äsja parimaks Euroopa filmiks tunnistatud "Teiste elu" ("Das Leben der Anderen"), mehhiklase Guillermo Del Toro "Paani labürint" ("El laberinto del fauno", Mehhiko - Hispaania 2006), itaallase Nanni Moretti "Kaiman" ("The Caiman")

The energy situation in year 2050; Energilaeget aar 2050

Energy Technology Data Exchange (ETDEWEB)

Azar, C.; Lindgren, K.; Hijino, E. [Chalmers Univ. of Technology, Goeteborg (Sweden). Dept. of Physical Resource Theory

1998-07-01

This study outlines the Swedish energy system for the case where international agreements have been reached to stabilize the atmospheric CO2 levels at 400-500 ppm. Energy scenarios for Sweden in 2050 examine the possibility to reduce emissions of CO2, phase-out nuclear power and still maintain high growth for the standard of living. In a `post-materialistic` scenario, a CO2 reduction of 75% is used, while the two `materialistic` scenarios use a reduction of 75% or 50%. In the materialistic scenarios, activities grow by 50%-100% in most sectors (markedly higher for some sectors, e.g. transportation). The post-materialistic scenarios has a lower growth. According to the authors, there exists no insurmountable technical or economic problems to realize these scenarios. Higher energy efficiency, increased use of renewable energy sources (in particular biofuels) and a modest use of natural gas will be sufficient for the energy supplies needed - about 5-20 % lower than 1995 100 refs, 24 figs, 11 tabs

Industrial trigeneration using ammonia-water absorption refrigeration systems (AAR)

International Nuclear Information System (INIS)

Colonna, Piero; Gabrielli, Sandro

2003-01-01

In many industrial processes there is a simultaneous need for electric power and refrigeration at low temperatures. Examples are in the food and chemical industries. Nowadays the increase in fuel prices and the ecological implications are giving an impulse to energy technologies that better exploit the primary energy source and integrated production of utilities should be considered when designing a new production plant. The number of so-called trigeneration systems installations (electric generator and absorption refrigeration plant) is increasing. If low temperature refrigeration is needed (from 0 to -40 deg. C), ammonia-water absorption refrigeration plants can be coupled to internal combustion engines or turbogenerators. A thermodynamic system study of trigeneration configurations using a commercial software integrated with specifically designed modules is presented. The study analyzes and compares heat recovery from the primary mover at different temperature levels. In the last section a simplified economic assessment that takes into account disparate prices in European countries compares conventional electric energy supply from the grid and optimized trigeneration plants in one test case (10 MW electric power, 7000 h/year)

Luupaljas hüljesnaine ja mineviku vangid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2010-01-01

PÖFFi filmidest: Neil Jordani "Undiin" (Iirimaa - USA, 2009), Debra Graniku "Luupaljas" (USA, 2010), Urszula Antoniaki "Ei midagi isiklikku" (Iirimaa - Holland, 2009) ja Juan Jose Campanella "Saladus nende silmades" (Hispaania - Argentiina, 2009)

Kefir

OpenAIRE

Koçak, Celalettin; Gürsel, Asuman

1981-01-01

Kefir çok eski bir fermente süt mamülü olup, hammaddesi keçi, koyun ve inek sütüdür. %0.6-0.8 alkol içermesi nedeniyle fermente süt içkisi olarak tanınır. Günümüzde kefirin birçok hastalıklar üzerindeki iyileştirici etkisinden dolayı önemi artmıştır. Kefir üretiminde fermantasyonu sağlamak üzere kefir tanelerinden yararlanılır. Kefir taneleri sarımtırak renkte olup takriben bezelye büyüklüğündedir. Bu taneler kazein ve birbirleri ile ortaklaşa yaşayan mikroorganizmaların meydana getirdiği j...

Kefir

OpenAIRE

Celalettin Koçak; Asuman Gürsel

2015-01-01

Kefir çok eski bir fermente süt mamülü olup, hammaddesi keçi, koyun ve inek sütüdür. %0.6-0.8 alkol içermesi nedeniyle fermente süt içkisi olarak tanınır. Günümüzde kefirin birçok hastalıklar üzerindeki iyileştirici etkisinden dolayı önemi artmıştır. Kefir üretiminde fermantasyonu sağlamak üzere kefir tanelerinden yararlanılır. Kefir taneleri sarımtırak renkte olup takriben bezelye büyüklüğündedir. Bu taneler kazein ve birbirleri ile ortaklaşa yaşayan mikroorganizmaların meydana getirdiği j...

Kefir

OpenAIRE

Koçak, Celalettin; Gürsel, Asuman

2014-01-01

Kefir çok eski bir fermente süt mamülü olup, hammaddesi keçi, koyun ve inek sütüdür. %0.6-0.8 alkol içermesi nedeniyle fermente süt içkisi olarak tanınır. Günümüzde kefirin birçok hastalıklar üzerindeki iyileştirici etkisinden dolayı önemi artmıştır. Kefir üretiminde fermantasyonu sağlamak üzere kefir tanelerinden yararlanılır. Kefir taneleri sarımtırak renkte olup takriben bezelye büyüklüğündedir. Bu taneler kazein ve birbirleri ile ortaklaşa yaşayan mikroorganizmaların meydana getirdiği j...

78 FR 78508 - Quarterly Rail Cost Adjustment Factor

Science.gov (United States)

2013-12-26

... (ICC) outlined the procedures for calculating the all-inclusive index of railroad input prices [[Page... Association of American Railroads (AAR) is required to calculate the index on a quarterly basis and submit it... Procedures--Productivity Adjustment, 5 I.C.C.2d 434 (1989), aff'd sub nom. Edison Electric Institute v. ICC...

Gallup : kirjandus, kirjanik, kriitika ja kriitik : [küsitlus

Index Scriptorium Estoniae

2005-01-01

Küsimustele vastavad: Jan Kaus, Arne Merilai, Aarne Ruben, Peeter Sauter, Asta Põldmäe, Aare Pilv, Arvo Valton, Lauri Sommer, Mari Laaniste, Toomas Raudam, Ivar Sild, Olev Remsu, Kalle Kurg, Fagira D Morti, Eeva Park, Neeme Lopp, Valle-Sten Maiste, Sirli Ojaste, Ene-Reet Soovik, Märt Väljataga, Indrek Mesikepp

Igavene eksport : [luuletused] / Kauksi Ülle

Index Scriptorium Estoniae

Kauksi Ülle, pseud., 1962-

2005-01-01

Sisu: Igavene eksport / võru keelest eesti keelde tõlkinud Aare Pilv ; "Sinno uika ma..." ; "Piaq vasta..." / võru keelest udmurdi keelde tõlkinud Irina Orehhova, Svetlana Ljubimova ; Paat ; Jummalhoitku / võru keelest udmurdi keelde tõlkinud Irina Orehhova, Pjotr Zahharov ; Säitsme vele sõsar / udmurdi keelde tõlkinud Pjotr Zahharov

Kas läheb ka Ruudi tapmiseks? / Kati Murutar

Index Scriptorium Estoniae

Murutar, Kati, 1967-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006. Võetud kõne alla ka Peeter Simmi "Kõrini!" ja Peeter Urbla "Stiilipeo" arvustaja meelest teenimatult mahategevad retsensioonid

Raamat / Matis Rodin

Index Scriptorium Estoniae

Rodin, Matis

2012-01-01

Tutvustus: Kalm, Mart. Rannalinn, seenrõdu ja viinakapp : Pärnu linnaarhitekt Olev Siinmaa. Eesti Arhitektuurimuuseum : Eesti Kunstiakadeemia, 2012; Olander, Aare. Kadunud vaated : Tallinna muutumine enam kui 400 fotol. Tänapäev, 2012; Mälestiste restaureerimine : enne ja pärast 2005-2011 / koostanud Britta Lainevool ja Ülo Puustak. Muinsuskaitseamet, 2011

NCBI nr-aa BLAST: CBRC-CFAM-23-0010 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-CFAM-23-0010 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 91% ...

NCBI nr-aa BLAST: CBRC-BTAU-01-3057 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-BTAU-01-3057 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 90% ...

Looduses sündinud looming / Margit Mald ; intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Mald, Margit

2009-01-01

2003. a. Haeskasse kolinud, Taanis Borholmi Klaasi- ja Keraamikakoolis end täiendanud keraamik Margit Mald endast, oma loomingust, esteetilistest tõekspidamistest, töökoja ja puupõletusahju ehitamisest Haeskasse. Margit Maldi näitus "Vorm läbi tule" Tallinnas galeriis Hop 22. juunini ja augustis Tartu Kunstimajas, kus lisaks on väljas seeria "50 rohelise tee tassi"

Andrus Kõresaar - porganditest pilvelõhkujani / Andrus Kõresaar ; intervjueerinud Tanel Veenre

Index Scriptorium Estoniae

Kõresaar, Andrus, 1975-

2009-01-01

Büroo KOKO Arhitektid ühest omanikust arhitekt Andrus Kõresaarest, tema loomingust, missioonist, koos KOKO Arhitektidega projekteeritud sünagoogist, ärihoonest Metro Plaza ja laudsepatöökoja rekonstrueerimisest Rotermanni kvartalis Tallinnas

Pikaajaline investor huvitub eelkõige äripinna renditulust / Tanel Veisson

Index Scriptorium Estoniae

Veisson, Tanel

2006-01-01

Ilmunud ka: Delovõje Vedomosti : Nedvizhimost 13. sept. lk. 15. Äripindade investeeringult teenitav tulu jaguneb kaheks: tegevustulu ja kapitalitulu. Pikaajalisi investoreid huvitab esimene, spekulante seevastu viimane

Kolm näitust, neli kunstnikku, sada õit / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2011-01-01

Imbi Ploompuu keraamika ja graafika näitus Eesti Tarbekunsti- ja Disainimuuseumis 4. sept.-ni. Kätrin Beljajevi ja Pilleriin Jürisoo ehtenäitus "Herbaarium" Tallinnas Iida galeriis 31. aug.-ni. Maiu Moosese ehtenäitus "Tänu" Tallinnas Hop-galeriis 19. juulini 2011. Linnainstallatsioonide festivali tööst "Audiotuur", autor arhitekt Kadri Klementi

Liberalistlik sissejuhatus poliitilisse filosoofiasse / Tanel Vallimäe, Peeter Selg

Index Scriptorium Estoniae

Vallimäe, Tanel, 1975-

2008-01-01

Vastukaja arvustusele: Reiland, Indrek. Normatiivse poliitikafilosoofia peateemad (Rets. rmt.: Wolff, Jonathan. Sissejuhatus poliitikafilosoofiasse / tlk. Tiiu Hallap. Tartu, 2005). Akadeemia, 2008, nr. 4, lk. 880-883

Piirivalve orkestri 11 unustamatut päeva Austraalias / Tanel Saarmann

Index Scriptorium Estoniae

Saarmann, Tanel

2008-01-01

Oma reisist Piirivalve Orkestriga Austraaliasse räägivad Arvi Miido, Raul Mäe ja Jüri Kalve. Lisa: Väljavõtted artiklist Adelaide'i kohalikus väliseesti ajalehes Virgats, 5. mai 2008 ; Mis on tattoo?

Küberrünnakute moos aprillirahutuste kibedal pudrul / Tanel Tammet

Index Scriptorium Estoniae

Tammet, Tanel

2008-01-01

Küberrünnakute põhimeetodist, eesmärkidest ning vastumeetmetest. 2007. aasta aprillikuistest küberrünnakutest Eesti vastu. Autor nendib, et suuremas plaanis oli küberrünnak Eesti vastu väike täpe maailmas pidevalt toimuvas sõjas võrgukanalite ümber, kuid selle eriliseks nüansiks oli puhtpoliitiline motiveeritus

Riik võib sundida ühe raudteefirma lahkuma / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Vt. ka: Narva Postiljon 12. juuli lk. 2. Valitsuse plaan osta lähiaastail 36 uut reisirongi ning anda nendega opereerimine ühele firmale sunniks turult lahkuma kas Edelaraudtee või Elektriraudtee. Lisa: Riik otsib Edelaraudteega üksmeelt

Narva ametnikku kahtlustatakse pistise nõudmises / Tanel Mazur, Aleksei Gorpintshenko

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2008-01-01

Autorite väitel võib Narva linnavalitsuse linnavara- ja majandusameti direktori kohusetäitja Arkadi Nikolajevi vahistamine olla seotud laiema korruptsiooniskeemiga. Skeem: Politsei uurib Arkadi Nikolajevi tegemisi

5 põhjust sukelduda Disainiöösse / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Kultuurifestivali Arts & Lights Disainiöö üritustest Tallinnas Rotermanni kvartalis 25.-27. sept. 2009. Näeb Reet Ausi kureeritud moevaatemängu "Kas oled kunagi mõelnud, miks elu on nagu on?", väljapanekut "Disaini Elevaator" Rotermanni elevaatoris, peetakse disainioksjon jm.

Viis sepapoissi näitavad raua tulist ilu / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2010-01-01

Eesti Kunstiakadeemia sepakunsti eriala tudengite Nils Hindi, Hans-Otto Ojaste, Urmas Lüüsi, Fred Truusi ja Jan Västeri näitus "Ferri canes" Dominiiklaste kloostri Mauritiuse Instituudis (Tallinn, Müürivahe 33) 30. juunini 2010

Juhan Parts lubab investeerida teedesse / Juhan Parts ; interv. Tanel Raig

Index Scriptorium Estoniae

Parts, Juhan, 1966-

2007-01-01

Ilmunud ka: Delovõje Vedomosti 17. okt. lk. 13. Majandusminister Juhan Parts arutleb lahendamist vajavate küsimuste ja prioriteetsete investeeringute üle transpordisektoris. Lisa: Juhan Partsi kuus kuud ministrina

Kunstiakadeemia lõpetajad 2005 / Karin Paulus, Tanel Veenre, Tõnu Kaalep

Index Scriptorium Estoniae

Paulus, Karin, 1975-

2005-01-01

Valik Eesti Kunstiakadeemia bakalaureusetöid: Elize Hiiobi "Nimeta ehe", Anton Kooviti uued kirjatüübid, Raili Ilmsalu kipsskulptuur "Eva", Aleksei Aljoshini "Futuristlik spordirõivas", Merle Kasoneni töö "Võimalused", Leena Lüteri draakon "Isiklik kaitsja", Ave Maseri miniatuurid "Teised", Kärt Põldmani "Punased kingad", Riho Tiiveli vetelpäästesüsteem, Ester Kannelmäe rõivakollektsioon "Ahistab", töö "Eesti rahvalaulud", Helena Vaidla mosaiik "Veesilm", Merike Estna kineetiline maal "Punamütsike: I am the Prettiest Girl in the World", Eilve Mangluse käeobjektid, Annike Oldre maal "Üksi", Eliisa Ehini töö "Närviimpulsside liikumine ajus", Veiko Vaine terrassitool "Miinimum"

Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model

Directory of Open Access Journals (Sweden)

Arheden Håkan

2010-09-01

Full Text Available Abstract Background Polymorphonuclear neutrophils, stimulated by the activated complement factor C5a, have been implicated in cardiac ischemia/reperfusion injury. ADC-1004 is a competitive C5a receptor antagonist that has been shown to inhibit complement related neutrophil activation. ADC-1004 shields the neutrophils from C5a activation before they enter the reperfused area, which could be a mechanistic advantage compared to previous C5a directed reperfusion therapies. We investigated if treatment with ADC-1004, according to a clinically applicable protocol, would reduce infarct size and microvascular obstruction in a large animal myocardial infarct model. Methods In anesthetized pigs (42-53 kg, a percutaneous coronary intervention balloon was inflated in the left anterior descending artery for 40 minutes, followed by 4 hours of reperfusion. Twenty minutes after balloon inflation the pigs were randomized to an intravenous bolus administration of ADC-1004 (175 mg, n = 8 or saline (9 mg/ml, n = 8. Area at risk (AAR was evaluated by ex vivo SPECT. Infarct size and microvascular obstruction were evaluated by ex vivo MRI. The observers were blinded to the treatment at randomization and analysis. Results ADC-1004 treatment reduced infarct size by 21% (ADC-1004: 58.3 ± 3.4 vs control: 74.1 ± 2.9%AAR, p = 0.007. Microvascular obstruction was similar between the groups (ADC-1004: 2.2 ± 1.2 vs control: 5.3 ± 2.5%AAR, p = 0.23. The mean plasma concentration of ADC-1004 was 83 ± 8 nM at sacrifice. There were no significant differences between the groups with respect to heart rate, mean arterial pressure, cardiac output and blood-gas data. Conclusions ADC-1004 treatment reduces myocardial ischemia-reperfusion injury and represents a novel treatment strategy of myocardial infarct with potential clinical applicability.

Buyid Silk and the Tale of Bibi Shahrbanu: Identification of Biomarkers of Artificial Aging (Forgery) of Silk.

Science.gov (United States)

Moini, Mehdi; Rollman, Christopher M

2017-10-03

Buyid silk forgery is one of the most famous silk forgeries in the world. In 1924-1925, excavation of the Bibi Shahrbanu site in Iran unearthed several silk textiles. The silks were thought to be of the Buyid period (934-1062 BCE) of the Persian Empire and have since been known as the "Buyid silks". In the 1930s, more silk appeared and was reported as being from the Buyid period as well. Controversy over the authenticity of these silks escalated after the purchase of the silks by museums throughout the world. Extensive investigations of several of these silks have been conducted over the years with respect to iconography, weaving patterns, dyes/mordant, style, and even radiocarbon dating. It was found that most of the silks are not from Buyid period. To test the authenticity of these silk fabrics, the recently developed silk dating technique using amino acid racemization (AAR) in conjunction with capillary electrophoresis mass spectrometry was applied to 13 Buyid silk specimens from the Textile Museum collections. Among these silk specimens, the AAR ratios of only one specimen were consistent with authentic silk fabrics collected from various museums. In addition, the aspartic acid racemization ratio of this specimen was also consistent with its 14 C dating. The other "Buyid silks" showed excessive levels of amino acid racemization not only for aspartic acid, but also for phenylalanine and tyrosine, inconsistent with racemization rates of these amino acids in authentic historical silk fabrics. Treatment of modern silk with a base at different pH and temperature reproduced the AAR pattern of the Buyid silks, implying that chemical treatment with a base at relatively high temperatures was perhaps the method used to artificially age these fabrics. The results imply that the racemization ratios of aspartic acid, phenylalanine, and tyrosine can be used as biomarkers for identification of naturally versus artificially aged silk.

Alkane Biosynthesis Genes in Cyanobacteria and Their Transcriptional Organization

International Nuclear Information System (INIS)

Klähn, Stephan; Baumgartner, Desirée; Pfreundt, Ulrike; Voigt, Karsten; Schön, Verena; Steglich, Claudia; Hess, Wolfgang R.

2014-01-01

In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl–acyl carrier protein reductase and aldehyde deformylating oxygenase. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short-chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado) and sll0209 (aar), which give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313, and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in cyanobacteria.

Reversible Unfolding of Rhomboid Intramembrane Proteases.

Science.gov (United States)

Panigrahi, Rashmi; Arutyunova, Elena; Panwar, Pankaj; Gimpl, Katharina; Keller, Sandro; Lemieux, M Joanne

2016-03-29

Denaturant-induced unfolding of helical membrane proteins provides insights into their mechanism of folding and domain organization, which take place in the chemically heterogeneous, anisotropic environment of a lipid membrane. Rhomboid proteases are intramembrane proteases that play key roles in various diseases. Crystal structures have revealed a compact helical bundle with a buried active site, which requires conformational changes for the cleavage of transmembrane substrates. A dimeric form of the rhomboid protease has been shown to be important for activity. In this study, we examine the mechanism of refolding for two distinct rhomboids to gain insight into their secondary structure-activity relationships. Although helicity is largely abolished in the unfolded states of both proteins, unfolding is completely reversible for HiGlpG but only partially reversible for PsAarA. Refolding of both proteins results in reassociation of the dimer, with a 90% regain of catalytic activity for HiGlpG but only a 70% regain for PsAarA. For both proteins, a broad, gradual transition from the native, folded state to the denatured, partly unfolded state was revealed with the aid of circular dichroism spectroscopy as a function of denaturant concentration, thus arguing against a classical two-state model as found for many globular soluble proteins. Thermal denaturation has irreversible destabilizing effects on both proteins, yet reveals important functional details regarding substrate accessibility to the buried active site. This concerted biophysical and functional analysis demonstrates that HiGlpG, with a simple six-transmembrane-segment organization, is more robust than PsAarA, which has seven predicted transmembrane segments, thus rendering HiGlpG amenable to in vitro studies of membrane-protein folding. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

[Comparison of various noninvasive serum markers of liver fibrosis in chronic viral liver disease].

Science.gov (United States)

Kim, Sun Min; Sohn, Joo Hyun; Kim, Tae Yeob; Roh, Young Wook; Eun, Chang Soo; Jeon, Yong Cheol; Han, Dong Soo; Oh, Young Ha

2009-12-01

The aim of this study was to determine the clinical performances of noninvasive serum markers for the prediction of liver fibrosis in chronic viral liver diseases. We analyzed a total of 225 patients with chronic viral liver diseases (180 with hepatitis B virus, 43 with hepatitis C virus, and 2 with hepatitis B+C virus) who underwent a liver biopsy procedure at the Hanyang University Guri Hospital between March 2002 and February 2007. Serum was also obtained at the time of liver biopsy. Liver fibrosis was staged according to the scoring system proposed by the Korean Study Group for the Pathology of Digestive Diseases. Various noninvasive serum markers were evaluated, including the aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio (AAR), age-platelet (AP) index, AST/platelet ratio index (APRI), cirrhosis discriminant score (CDS), platelet count, hyaluronic acid (HA), and type IV collagen. There were 17, 40, 61, 74, and 33 patients at stages F0, F1, F2, F3, and F4, respectively. The overall diagnostic accuracies of each marker, as determined by the area under receiver operating characteristics curves, were APRI=0.822, CDS=0.776, platelet count=0.773, AP index=0.756, HA=0.749, type IV collagen=0.718, and AAR=0.642 for predicting significant fibrosis (> or =F2); and CDS=0.835, platelet count=0.795, AP index=0.794, HA=0.766, AAR=0.711, type IV collagen=0.697, and APRI=0.691 for predicting extensive fibrosis (> or =F3). All noninvasive serum markers evaluated in this study were useful for predicting significant or extensive liver fibrosis in chronic viral liver diseases. In particular, APRI was most useful for the prediction of significant fibrosis, and CDS was most useful for the prediction of extensive fibrosis.

Alkane Biosynthesis Genes in Cyanobacteria and Their Transcriptional Organization

Energy Technology Data Exchange (ETDEWEB)

Klähn, Stephan; Baumgartner, Desirée; Pfreundt, Ulrike; Voigt, Karsten; Schön, Verena; Steglich, Claudia; Hess, Wolfgang R., E-mail: wolfgang.hess@biologie.uni-freiburg.de [Genetics and Experimental Bioinformatics, Institute of Biology 3, Faculty of Biology, University of Freiburg, Freiburg (Germany)

2014-07-14

In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl–acyl carrier protein reductase and aldehyde deformylating oxygenase. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short-chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado) and sll0209 (aar), which give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313, and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in cyanobacteria.

Prediction of esophageal varices and variceal hemorrhage in patients with acute upper gastrointestinal bleeding.

Science.gov (United States)

Rockey, Don C; Elliott, Alan; Lyles, Thomas

2016-03-01

In patients with upper gastrointestinal bleeding (UGIB), identifying those with esophageal variceal hemorrhage prior to endoscopy would be clinically useful. This retrospective study of a large cohort of patients with UGIB used logistic regression analyses to evaluate the platelet count, aspartate aminotransferase (AST) to platelet ratio index (APRI), AST to alanine aminotransferase (ALT) ratio (AAR) and Lok index (all non-invasive blood markers) as predictors of variceal bleeding in (1) all patients with UGIB and (2) patients with cirrhosis and UGIB. 2233 patients admitted for UGIB were identified; 1034 patients had cirrhosis (46%) and of these, 555 patients (54%) had acute UGIB due to esophageal varices. In all patients with UGIB, the platelet count (cut-off 122,000/mm(3)), APRI (cut-off 5.1), AAR (cut-off 2.8) and Lok index (cut-off 0.9) had area under the curve (AUC)s of 0.80 0.82, 0.64, and 0.80, respectively, for predicting the presence of varices prior to endoscopy. To predict varices as the culprit of bleeding, the platelet count (cut-off 69,000), APRI (cut-off 2.6), AAR (cut-off 2.5) and Lok Index (0.90) had AUCs of 0.76, 0.77, 0.57 and 0.73, respectively. Finally, in patients with cirrhosis and UGIB, logistic regression was unable to identify optimal cut-off values useful for predicting varices as the culprit bleeding lesion for any of the non-invasive markers studied. For all patients with UGIB, non-invasive markers appear to differentiate patients with varices from those without varices and to identify those with a variceal culprit lesion. However, these markers could not distinguish between a variceal culprit and other lesions in patients with cirrhosis. Copyright © 2016 American Federation for Medical Research.

Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine.

Science.gov (United States)

Kurnik, Daniel; Muszkat, Mordechai; Li, Chun; Sofowora, Gbenga G; Friedman, Eitan A; Scheinin, Mika; Wood, Alastair J J; Stein, C Michael

2011-04-01

α(2A)-Adrenoceptors (α(2A)-ARs) have important roles in sympathetic cardiovascular regulation. Variants of ADRA2A affect gene transcription and expression and are associated with insulin release and risk for type 2 diabetes. We examined whether ADRA2A variants are also associated with cardiovascular responses to the selective α(2)-AR-agonist dexmedetomidine. Seventy-three healthy subjects participated in a placebo-controlled, single-blind study. After 3 infusions of placebo, subjects received 3 incremental infusions of dexmedetomidine (cumulative dose, 0.4 μg/kg). Primary outcomes were changes in systolic blood pressure (SBP) and plasma norepinephrine concentrations, measured as difference of the area-under-the-curve during placebo and dexmedetomidine infusions (ΔAUC). We used multiple linear regression analysis to examine the associations between 9 ADRA2A tagging variants and 5 inferred haplotypes and ΔAUC after adjustment for covariates. Homozygous carriers of rs553668 and the corresponding haplotype 4, previously associated with increased α(2A)-AR expression, had a 2.2-fold greater decrease in AUC(SBP) after dexmedetomidine (adjusted P=0.006); similarly, the maximum decrease in SBP was 24.7±8.1 mm Hg compared with 13.6±5.9 mm Hg in carriers of the wild-type allele (P=0.007). Carriers of haplotype 3, previously associated with reduced α(2A)-AR expression, had a 44% smaller decrease in AUC(SBP) (P=0.013). Haplotype information significantly improved the model predicting the decrease in SBP (Pblood pressure and heart rate. Genotypes were not significantly associated with norepinephrine responses. Common ADRA2A variants are associated with the hypotensive response to dexmedetomidine. Effects of specific variants/haplotypes in vivo are compatible with their known effects on gene expression in vitro.

Ostetud lõputööga saaks ülikoolidiplomi kätte küll / Kristi Leppik

Index Scriptorium Estoniae

Leppik, Kristi

2008-01-01

Plagiaadist, autoriõigusest ja lõputööde ostmisest ajakirjandusliku eksperimendina korraldatud õigusteaduse bakalaureuse lõputöö hankimise näitel Kommenteerivad Tallinna Tehnikaülikooli ehitusteaduskonna dekaan Roode Liias, Akadeemia Nord õigusteaduste dekaan Aare Kruuser, Tartu Ülikooli majandusteaduskonna arenduspordekaan Jüri Sepp, Tallinna Ülikooli riigireaduste instituudi direktor Leif Kalev

Short outlines of books by Estonian authors / Janika Kronberg and Rutt Hinrikus

Index Scriptorium Estoniae

Kronberg, Janika, 1963-

2010-01-01

Arvustus: Käsper, Kalle. Buridanid. I-V. Tallinn : Eesti Keele Sihtasutus, 2005-2010 ; Kivastik, Mart. Eesti asjad. Tartu : Kaks Musketäri, 2010 ; Kangro, Maarja. Ahvid ja solidaarsus. Tallinn : Eesti keele Sihtasutus, 2010 ; Põder, Rein. Unustatud. Tallinn : Eesti Raamat, 2010 ; Kesküla, Kalev. Elu sumedusest. Tallinn : Tuum, 2009 ; Pilv, Aare. Ramadaan. Tallinn : Tuum, 2010

Tallinna Merepäevade turismikonverents

Index Scriptorium Estoniae

2012-01-01

13. juulil Lennusadama angaarides toimunud turismikonverentsist "Lennukad ideed Lennusadamas", kus esinesid Tallinna abilinnapea Taavi Aas, Tallinna Sadama ärisuunajuht Ahto Ader, müügijuht Aare Maurer, EHTE arenduse ja uuringute osakonna juhataja Ain Hinsberg, kes rääkis projektist "Cultural Tourism 2011", Tallinna Lennujaama juhatuse esimees Rein Loik, Lennusadama tegevjuht Ott Sarapuu

Miks halvustada konkurenti? / Timo Riismaa

Index Scriptorium Estoniae

Riismaa, Timo

2006-01-01

Konkureeriva ettevõtte toodete halvustamisest. ThermiSol OÜ ja Saint Gobain Isover Eesti AS-i vahelisest kohtuasjast. Vt. ka: Kas Eesti tootjad halvustavad üksteise tooteid? Küsimusele vastavad Reiden Plaat AS-i müügijuht Aldo Unga, OÜ V-Temps juhataja Aare Võsu ja Saint-Gobain Isover Eesti AS-i marketingijuht Hellart Kala

David Lynchi lamella / Slavoj Žižek ; tõlkinud Hasso Krull

Index Scriptorium Estoniae

Žižek, Slavoj, 1949-

1996-01-01

Režissöör ja tema filmide psühhoanalüütiline analüüs, tõlge kogumikust "Reading Seminar XI. Lacan's Four Fundamental Concepts of Psychoanalysis", 1995. Lisad : tõlkija seletab sõna "lamella" tähenduse, Aare Ermeli koostatud režissööri filmograafia (mittetäielik)

Peamise Oscari näppas "Kokkupõrge" / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2006-01-01

Kuidas ja miks juhtus, et 78. Ameerika Filmiakadeemia Oscari-tseremoonial kuulutati parimaks filmiks Paul Haggise "Kokkupõrge" ("Crash") seni üldiselt favoriidiks peetud Ang Lee "Brokebacki mäe" ("Brokeback Mountain") asemel. Lisatud arvamused, mille autoriteks Aare Tilk ja Ilmar Raag ning Timo Dieneri vastus küsimusele "Kas "Kokkupõrge" jõuab ka Eestisse?"

NCBI nr-aa BLAST: CBRC-GACU-23-0054 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-GACU-23-0054 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 4e-55 36% ...

NCBI nr-aa BLAST: CBRC-XTRO-01-3489 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-XTRO-01-3489 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 1e-151 78% ...

NCBI nr-aa BLAST: CBRC-PMAR-01-0530 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-PMAR-01-0530 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 6e-69 42% ...

NCBI nr-aa BLAST: CBRC-OLAT-26-0036 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-OLAT-26-0036 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 1e-55 36% ...

NCBI nr-aa BLAST: CBRC-DRER-07-0075 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-DRER-07-0075 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 9e-57 36% ...

A guidance law for UAV autonomous aerial refueling based on the iterative computation method

Directory of Open Access Journals (Sweden)

Luo Delin

2014-08-01

Full Text Available The rendezvous and formation problem is a significant part for the unmanned aerial vehicle (UAV autonomous aerial refueling (AAR technique. It can be divided into two major phases: the long-range guidance phase and the formation phase. In this paper, an iterative computation guidance law (ICGL is proposed to compute a series of state variables to get the solution of a control variable for a UAV conducting rendezvous with a tanker in AAR. The proposed method can make the control variable converge to zero when the tanker and the UAV receiver come to a formation flight eventually. For the long-range guidance phase, the ICGL divides it into two sub-phases: the correction sub-phase and the guidance sub-phase. The two sub-phases share the same iterative process. As for the formation phase, a velocity coordinate system is created by which control accelerations are designed to make the speed of the UAV consistent with that of the tanker. The simulation results demonstrate that the proposed ICGL is effective and robust against wind disturbance.

Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins

International Nuclear Information System (INIS)

Sung, Uhna; Jennings, Jennifer L.; Link, Andrew J.; Blakely, Randy D.

2005-01-01

The norepinephrine transporter (NET) terminates noradrenergic signals by clearing released NE at synapses. NET regulation by receptors and intracellular signaling pathways is supported by a growing list of associated proteins including syntaxin1A, protein phosphatase 2A (PP2A) catalytic subunit (PP2A-C), PICK1, and Hic-5. In the present study, we sought evidence for additional partnerships by mass spectrometry-based analysis of proteins co-immunoprecipitated with human NET (hNET) stably expressed in a mouse noradrenergic neuroblastoma cell line. Our initial proteomic analyses reveal multiple peptides derived from hNET, peptides arising from the mouse PP2A anchoring subunit (PP2A-Ar) and peptides derived from 14-3-3 proteins. We verified physical association of NET with PP2A-Ar via co-immunoprecipitation studies using mouse vas deferens extracts and with 14-3-3 via a fusion pull-down approach, implicating specifically the hNET NH 2 -terminus for interactions. The transporter complexes described likely support mechanisms regulating transporter activity, localization, and trafficking

Cardiorespiratory responses and reduced apneic time to cold-water face immersion after high intensity exercise.

Science.gov (United States)

Konstantinidou, Sylvia; Soultanakis, Helen

2016-01-01

Apnea after exercise may evoke a neurally mediated conflict that may affect apneic time and create a cardiovascular strain. The physiological responses, induced by apnea with face immersion in cold water (10 °C), after a 3-min exercise bout, at 85% of VO2max,were examined in 10 swimmers. A pre-selected 40-s apnea, completed after rest (AAR), could not be met after exercise (AAE), and was terminated with an agonal gasp reflex, and a reduction of apneic time, by 75%. Bradycardia was evident with immersion after both, 40-s of AAR and after AAE (P<0.05). The dramatic elevation of, systolic pressure and pulse pressure, after AAE, were indicative of cardiovascular stress. Blood pressure after exercise without apnea was not equally elevated. The activation of neurally opposing functions as those elicited by the diving reflex after high intensity exercise may create an autonomic conflict possibly related to oxygen-conserving reflexes stimulated by the trigeminal nerve, and those elicited by exercise. Copyright © 2015. Published by Elsevier B.V.

Exact docking flight controller for autonomous aerial refueling with back-stepping based high order sliding mode

Science.gov (United States)

Su, Zikang; Wang, Honglun; Li, Na; Yu, Yue; Wu, Jianfa

2018-02-01

Autonomous aerial refueling (AAR) exact docking control has always been an intractable problem due to the strong nonlinearity, the tight coupling of the 6 DOF aircraft model and the complex disturbances of the multiple environment flows. In this paper, the strongly coupled nonlinear 6 DOF model of the receiver aircraft which considers the multiple flow disturbances is established in the affine nonlinear form to facilitate the nonlinear controller design. The items reflecting the influence of the unknown flow disturbances in the receiver dynamics are taken as the components of the "lumped disturbances" together with the items which have no linear correlation with the virtual control variables. These unmeasurable lumped disturbances are estimated and compensated by a specially designed high order sliding mode observer (HOSMO) with excellent estimation property. With the compensation of the estimated lumped disturbances, a back-stepping high order sliding mode based exact docking flight controller is proposed for AAR in the presence of multiple flow disturbances. Extensive simulation results demonstrate the feasibility and superiority of the proposed docking controller.

Early Gadolinium Enhancement for Determination of Area at Risk

DEFF Research Database (Denmark)

Hammer-Hansen, Sophia; Leung, Steve W; Hsu, Li-Yueh

2017-01-01

OBJECTIVES: The aim of this study was to determine whether early gadolinium enhancement (EGE) by cardiac magnetic resonance (CMR) in a canine model of reperfused myocardial infarction depicts the area at risk (AAR) as determined by microsphere blood flow analysis. BACKGROUND: It remains controver......OBJECTIVES: The aim of this study was to determine whether early gadolinium enhancement (EGE) by cardiac magnetic resonance (CMR) in a canine model of reperfused myocardial infarction depicts the area at risk (AAR) as determined by microsphere blood flow analysis. BACKGROUND: It remains...... requires pathological validation. METHODS: Eleven dogs underwent 2 h of coronary artery occlusion and 48 h of reperfusion before imaging at 1.5-T. EGE imaging was performed 3 min after contrast administration with coverage of the entire left ventricle. Late gadolinium enhancement imaging was performed...... on native T1 and T2 maps. The size of EGE was significantly greater than the infarct by triphenyltetrazolium chloride (44.1 ± 15.8% vs. 20.7 ± 14.4%; p gadolinium enhancement (44.1 ± 15.8% vs. 23.5 ± 12.7%; p

Problem-Based Learning: Instructor Characteristics, Competencies, and Professional Development

Science.gov (United States)

2011-01-01

instructional segment addresses multiple competencies in a situated, naturalistic context via a sequence of classroom observation , after action review, follow...Exercise 1. Classroom observation 2. AAR 3. Direct instruction 4. Deliberate Practice 5. Field Experience 29 Table 1. Notional lesson plan for PBL...Direct Instruction, Knowledge Games 2 Reading Students - Monitor & Intervene - Facilitate Collaboration Classroom Observation #1, After Action

78 FR 59093 - Quarterly Rail Cost Adjustment Factor

Science.gov (United States)

2013-09-25

... (ICC) outlined the procedures for calculating the all-inclusive index of railroad input prices and the... American Railroads (AAR) is required to calculate the index on a quarterly basis and submit it to the...--Productivity Adjustment, 5 I.C.C. 2d 434 (1989), aff'd sub nom. Edison Electric Institute v. ICC, 969 F.2d 1221...

Paraadile annavad sära sõjaväeorkestrid. Kultuuri ja uunikumi / Andris Tammela

Index Scriptorium Estoniae

Tammela, Andris

2005-01-01

Võidupüha üritustest Paides 23. juunil. Suure-Jaani muusikapäevadest: Mati Palmi ja Aare-Paul Lattiku kontsert 22. juun. Suure-Jaani jahimajas, Sven Grünbergi, Lilian Langsepa ja Vambola Kriguli kontsert 22. juun. Suure-Jaani kirikus, Urmas Sisaski autoriõhtu 23. juun. Suure-Jaani kirikus, Jassi Zahharovi kontsert 23. juun. Soomaal Hüpassaares

Scenario Selection and Student Assessment Modules for CyberCIEGE

National Research Council Canada - National Science Library

Leng, Tiat

2003-01-01

.... In addition by tapping the CyberCIEGE event log files generated at the end of each game, we can reconstruct the game progress to support After Action Reviews (AAR) to assist the instructor and student to analyze game decisions and the student's progress. This provides a constructive follow-up to review and reinforce the concepts being taught.

Ettevõtjatel puudub logistikast terviknägemus : parim ladu on veoauto kast / Reigo Kuivjõgi

Index Scriptorium Estoniae

Kuivjõgi, Reigo

2000-01-01

Kuna ettevõtetel puudub sageli logistika terviklik koordineerimine ja kulude analüüs, on liigsed logistikakulud firma majandustulemustele suureks koormaks. Logistikateemalisest ümarlauakohtumisest võtsid osa Tallinna Tehnikakõrgkooli prorektor Enno Lend, Tallinna Tehnikaülikooli professor Aare Uustalu, Schenker-BTL-i logistikadirektor Ain Tulvi, Schenker-BTL-i tegevdirektor Meelis Arumeel ja Eesti Kaubaliinide juhataja Tõnis Hintsov

English for lawyers / Liina Soobik ; [preface: Peep Pruks

Index Scriptorium Estoniae

Soobik, Liina, 1955-

2001-01-01

Kasutatud tekstide autorid: Peep Pruks, Merit-Ene Ilja, Ilona Nurmela, Kristi Raba, Andreas Kangur, Raul Narits, Peeter Roosma, Kalle Merusk, Maret Altnurme, Jaan Ginter, Aare Tark, Norman Aas, Lasse Lehis, Hannes Veinla, Jaan Sootak, Eerik Kergandberg, Paul Varul, Jaanus Ots, Urve Liin, Irene Kull, Merle Muda, Gaabriel Tavits, Andres Vutt, Kadri Siibak, Ellen Ridaste, Heiki Pisuke, Andrus Siibak

D IE ROOM SE LUTHER SE EN HERVORMDEB ESK OU IN ...

African Journals Online (AJOL)

Test

Oor die leerstuk van die heilige Avondmaal neem Luther 'n tussen- standpunt in tussen die Roomse Kerk en die Hervormde Kerk. W aar. Rome leer dat die brood en die wyn by die bediening van die Avond maal waarlik in die vlees en bloed van Christus verander word, sodat die Avondmaalganger waarlik die liggaam van ...

NCBI nr-aa BLAST: CBRC-MDOM-07-0106 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MDOM-07-0106 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 88% ...

NCBI nr-aa BLAST: CBRC-TTRU-01-1190 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-TTRU-01-1190 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 91% ...

NCBI nr-aa BLAST: CBRC-MLUC-01-0485 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MLUC-01-0485 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 91% ...