78 FR 28152 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2013-05-14

...-0416; Directorate Identifier 2012-NM-144-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... A318-111 and -112 airplanes, Model A319 series airplanes, Model A320 series airplanes, and Model A321 series airplanes. The existing AD currently requires repetitive inspections of the 80VU rack lower...

77 FR 57003 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2012-09-17

... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, and A320 series airplanes. This AD was prompted by a report of a torn out.... The FAA amends Sec. 39.13 by adding the following new AD: 2012-18-12 Airbus: Amendment 39-17189...

77 FR 39186 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2012-07-02

...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A318, A319, A320, and... identified in this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte... 200, Suite 400, College Park, Georgia 30337; telephone 678-228-8153; fax 404-599-0041; email techpubs...

Resonance – Journal of Science Education | News

Indian Academy of Sciences (India)

Issue front cover thumbnail Issue back cover thumbnail. Volume 17, Issue 4. April 2012, pages 317-428. pp 317-318 Editorial. Editorial · G K Ananthasuresh · More Details Fulltext PDF. pp 319-320 Article-in-a-Box. Rudolf Diesel - The Rational Inventor of a Heat Engine · Tilottama Shrinivasa · More Details Fulltext PDF.

20 CFR 30.319 - May a claimant request reconsideration of a final decision of the FAB?

Science.gov (United States)

2010-04-01

... final decision of the FAB? 30.319 Section 30.319 Employees' Benefits OFFICE OF WORKERS' COMPENSATION... reconsideration of a final decision of the FAB? (a) A claimant may request reconsideration of a final decision of the FAB by filing a written request with the FAB within 30 days from the date of issuance of such...

The New Sun-Sky-Lunar Cimel CE318-T Multiband Photometer - A Comprehensive Performance Evaluation

Science.gov (United States)

Barreto, Africa; Cuevas, Emilio; Granados-Munoz, Maria-Jose; Alados-Arboledas, Lucas; Romero, Pedro M.; Grobner, Julian; Kouremeti, Natalia; Almansa, Antonio F.; Stone, Tom; Toledano, Carlos;

36 CFR 3.19 - May I operate a submersible within park waters?

Science.gov (United States)

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false May I operate a submersible within park waters? 3.19 Section 3.19 Parks, Forests, and Public Property NATIONAL PARK SERVICE... waters? The use of manned or unmanned submersibles may only occur in accordance with a permit issued by...

MiR-320a as a Potential Novel Circulating Biomarker of Arrhythmogenic CardioMyopathy.

Science.gov (United States)

Sommariva, Elena; D'Alessandra, Yuri; Farina, Floriana Maria; Casella, Michela; Cattaneo, Fabio; Catto, Valentina; Chiesa, Mattia; Stadiotti, Ilaria; Brambilla, Silvia; Dello Russo, Antonio; Carbucicchio, Corrado; Vettor, Giulia; Riggio, Daniela; Sandri, Maria Teresa; Barbuti, Andrea; Vernillo, Gianluca; Muratori, Manuela; Dal Ferro, Matteo; Sinagra, Gianfranco; Moimas, Silvia; Giacca, Mauro; Colombo, Gualtiero Ivanoe; Pompilio, Giulio; Tondo, Claudio

2017-07-06

Diagnosis of Arrhythmogenic CardioMyopathy (ACM) is challenging and often late after disease onset. No circulating biomarkers are available to date. Given their involvement in several cardiovascular diseases, plasma microRNAs warranted investigation as potential non-invasive diagnostic tools in ACM. We sought to identify circulating microRNAs differentially expressed in ACM with respect to Healthy Controls (HC) and Idiopathic Ventricular Tachycardia patients (IVT), often in differential diagnosis. ACM and HC subjects were screened for plasmatic expression of 377 microRNAs and validation was performed in 36 ACM, 53 HC, 21 IVT. Variable importance in data partition was estimated through Random Forest analysis and accuracy by Receiver Operating Curves. Plasmatic miR-320a showed 0.53 ± 0.04 fold expression difference in ACM vs. HC (p ACM (n = 13) and HC (n = 17) with athletic lifestyle, a ACM precipitating factor. Importantly, ACM patients miR-320a showed 0.78 ± 0.05 fold expression change vs. IVT (p = 0.03). When compared to non-invasive ACM diagnostic parameters, miR-320a ranked highly in discriminating ACM vs. IVT and it increased their accuracy. Finally, miR-320a expression did not correlate with ACM severity. Our data suggest that miR-320a may be considered a novel potential biomarker of ACM, specifically useful in ACM vs. IVT differentiation.

Microstructure and mechanical properties of thixoformed A319 aluminium alloy

International Nuclear Information System (INIS)

Salleh, M.S.; Omar, M.Z.; Syarif, J.; Alhawari, K.S.; Mohammed, M.N.

2014-01-01

Highlights: • A319 was successfully thixoformed at 50% liquid, i.e. at 571 °C. • T6 heat treatment has increased the strength and hardness of the thixoformed alloy. • The elongation after T6 heat treatment is even significantly improved. • The iron-rich intermetallic phase reduces the strength of the thixoformed alloy. - Abstract: Thixoforming is a viable technology for forming alloys in a semisolid state into near net-shaped products. In the present study, the effect of a thixoforming process on the microstructure and mechanical properties of A319 aluminium alloy was investigated. The ingots obtained from the cooling slope were thixoformed in a press after they remained at 571 °C for 5 min, yielding a microstructure predominantly composed of α-Al globules and inter-globular Si particles. Some of the thixoformed samples were treated with an ageing process (T6) and then, hardness and tensile samples were prepared from the as-cast, as-thixoformed and thixoformed T6. All the thixoformed samples were characterised using optical microscopy, scanning electron microscopy (SEM), energy dispersive X-ray (EDX) and X-ray diffraction (XRD) as well as hardness measurements and tensile tests. The results indicate that the mechanical properties of the thixoformed A319 alloy increased after the T6 heat treatment (hardness of 124.2 ± 3.2 HV, tensile strength of 298 ± 3.0 MPa, yield strength of 201 ± 2.6 MPa and elongation to fracture of 4.5 ± 0.3%). The fracture samples from the tensile test were analysed, revealing that the iron-rich intermetallic observed in the samples reduced the tensile strength and ductility of the thixoformed A319 alloys

In cellulo phosphorylation of XRCC4 Ser320 by DNA-PK induced by DNA damage

International Nuclear Information System (INIS)

Sharma, Mukesh Kumar; Imamichi, Shoji; Fukuchi, Mikoto; Samarth, Ravindra Mahadeo; Tomita, Masanori; Matsumoto, Yoshihisa

2016-01-01

XRCC4 is a protein associated with DNA Ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end joining. In response to treatment with ionizing radiation or DNA damaging agents, XRCC4 undergoes DNA-PK-dependent phosphorylation. Furthermore, Ser260 and Ser320 (or Ser318 in alternatively spliced form) of XRCC4 were identified as the major phosphorylation sites by purified DNA-PK in vitro through mass spectrometry. However, it has not been clear whether these sites are phosphorylated in vivo in response to DNA damage. In the present study, we generated an antibody that reacts with XRCC4 phosphorylated at Ser320 and examined in cellulo phosphorylation status of XRCC4 Ser320. The phosphorylation of XRCC4 Ser320 was induced by γ-ray irradiation and treatment with Zeocin. The phosphorylation of XRCC4 Ser320 was detected even after 1 Gy irradiation and increased in a manner dependent on radiation dose. The phosphorylation was observed immediately after irradiation and remained mostly unchanged for up to 4 h. The phosphorylation was inhibited by DNA-PK inhibitor NU7441 and was undetectable in DNA-PKcs-deficient cells, indicating that the phosphorylation was mainly mediated by DNA-PK. These results suggested potential usefulness of the phosphorylation status of XRCC4 Ser320 as an indicator of DNA-PK functionality in living cells

MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting β-catenin

International Nuclear Information System (INIS)

Sun, Jian-Yong; Huang, Yi; Li, Ji-Peng; Zhang, Xiang; Wang, Lei; Meng, Yan-Ling; Yan, Bo; Bian, Yong-Qian; Zhao, Jing; Wang, Wei-Zhong

2012-01-01

Highlights: ► miR-320a is downregulated in human colorectal carcinoma. ► Overexpression of miR-320a inhibits colon cancer cell proliferation. ► β-Catenin is a direct target of miR-320a in colon cancer cells. ► miR-320a expression inversely correlates with mRNA expression of β-catenin’s target genes in human colon carcinoma. -- Abstract: Recent profile studies of microRNA (miRNA) expression have documented a deregulation of miRNA (miR-320a) in human colorectal carcinoma. However, its expression pattern and underlying mechanisms in the development and progression of colorectal carcinoma has not been elucidated clearly. Here, we performed real-time PCR to examine the expression levels of miR-320a in colon cancer cell lines and tumor tissues. And then, we investigated its biological functions in colon cancer cells by a gain of functional strategy. Further more, by the combinational approaches of bioinformatics and experimental validation, we confirmed target associations of miR-320a in colorectal carcinoma. Our results showed that miR-320a was frequently downregulated in cancer cell lines and colon cancer tissues. And we demonstrated that miR-320a restoration inhibited colon cancer cell proliferation and β-catenin, a functionally oncogenic molecule was a direct target gene of miR-320a. Finally, the data of real-time PCR showed the reciprocal relationship between miR-320a and β-catenin’s downstream genes in colon cancer tissues. These findings indicate that miR-320a suppresses the growth of colon cancer cells by directly targeting β-catenin, suggesting its application in prognosis prediction and cancer treatment.

MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting {beta}-catenin

Energy Technology Data Exchange (ETDEWEB)

Sun, Jian-Yong [State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 710032 Xi' an (China); Huang, Yi [Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, 710032 Xi' an (China); Li, Ji-Peng [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 710032 Xi' an (China); Zhang, Xiang; Wang, Lei [State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); Meng, Yan-Ling [Department of Immunology, Fourth Military Medical University, 710032 Xi' an (China); Yan, Bo [State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); Bian, Yong-Qian [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 710032 Xi' an (China); Zhao, Jing [State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, 710032 Xi' an (China); Wang, Wei-Zhong, E-mail: weichang@fmmu.edu.cn [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 710032 Xi' an (China); and others

2012-04-20

Highlights: Black-Right-Pointing-Pointer miR-320a is downregulated in human colorectal carcinoma. Black-Right-Pointing-Pointer Overexpression of miR-320a inhibits colon cancer cell proliferation. Black-Right-Pointing-Pointer {beta}-Catenin is a direct target of miR-320a in colon cancer cells. Black-Right-Pointing-Pointer miR-320a expression inversely correlates with mRNA expression of {beta}-catenin's target genes in human colon carcinoma. -- Abstract: Recent profile studies of microRNA (miRNA) expression have documented a deregulation of miRNA (miR-320a) in human colorectal carcinoma. However, its expression pattern and underlying mechanisms in the development and progression of colorectal carcinoma has not been elucidated clearly. Here, we performed real-time PCR to examine the expression levels of miR-320a in colon cancer cell lines and tumor tissues. And then, we investigated its biological functions in colon cancer cells by a gain of functional strategy. Further more, by the combinational approaches of bioinformatics and experimental validation, we confirmed target associations of miR-320a in colorectal carcinoma. Our results showed that miR-320a was frequently downregulated in cancer cell lines and colon cancer tissues. And we demonstrated that miR-320a restoration inhibited colon cancer cell proliferation and {beta}-catenin, a functionally oncogenic molecule was a direct target gene of miR-320a. Finally, the data of real-time PCR showed the reciprocal relationship between miR-320a and {beta}-catenin's downstream genes in colon cancer tissues. These findings indicate that miR-320a suppresses the growth of colon cancer cells by directly targeting {beta}-catenin, suggesting its application in prognosis prediction and cancer treatment.

Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

DEFF Research Database (Denmark)

Liu, Dekang; Frederiksen, Jane H.; Liberti, Sascha Emilie

2017-01-01

DNA mismatch repair (MMR) is a highly-conserved DNA repair mechanism, whose primary role is to remove DNA replication errors preventing them from manifesting as mutations, thereby increasing the overall genome stability. Defects in MMR are associated with increased cancer risk in humans and other...... organisms. Here, we characterize the interaction between MMR and a proofreading-deficient allele of the human replicative DNA polymerase delta, PolδD316A;E318A, which has a higher capacity for strand displacement DNA synthesis than wild type Polδ. Human cell lines overexpressing PolδD316A;E318A display...

GEA CRDA Range Data Analysis

Science.gov (United States)

1999-07-28

E1, July-August 1998 18 3.3. Example 3: SatMex, Solidaridad 2, May-June 1998 27 3.4. Example 4: PanAmSat, Galaxy IV, May-June 1998 33 3.5...17 Millstone measurements residuals for Telstar 401 on Days 181-263. 26 3-18 Millstone measurement residuals for Solidaridad 1 on Days 141-153...with 29 SatMex range data. 3-19 Hermosillo B-- Solidaridad 1 range residuals through Days 135-144 with bias 30 removed. 3-20 Iztapalapa D

9 CFR 3.18 - Terminal facilities.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Terminal facilities. 3.18 Section 3.18... Cats 1 Transportation Standards § 3.18 Terminal facilities. (a) Placement. Any person subject to the... inanimate cargo in animal holding areas of terminal facilities. (b) Cleaning, sanitization, and pest control...

49 CFR 178.318-2 - Container.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Container. 178.318-2 Section 178.318-2... Specifications for Containers for Motor Vehicle Transportation § 178.318-2 Container. (a) Every container for... individual cell in the body of the container, into which each such cap shall snugly fit. There shall be...

Suicide with One Cranial Gunshot by a .320 Caliber Pocket Revolver

Directory of Open Access Journals (Sweden)

Lucia Tattoli

2015-05-01

Full Text Available Suicide using a firearm is the most commonly used method of committing suicide for men and women. In this paper, we present and discuss a suicide case in which an 86-year-old man shot himself using a .320 caliber pocket revolver. Proper crime scene investigation, recovery of the weapon used, and precise interpretation of autopsy findings play a fundamental role in determining the exact cause and manner of death. Accurate analysis of the injuries and a thorough knowledge of weapons and ballistics are essential for an adequate investigation in these unusual cases. To the best of our knowledge, this is the first report of a cranial gunshot inflicted by a .320 caliber pocket revolver.

A soluble form of the transcobalamin receptor CD320 can be detected in human serum

DEFF Research Database (Denmark)

Arendt, Johan Frederik Berg; Quadros, Edward V.; Christensen, Anna Lisa

2010-01-01

Background: Recently, the cell-surface receptor involved in the internalisation of the cobalamin(vitamin B12, Cbl) transporting protein, transcobalamin(TC), was described, and was found to be CD320(1). So far, it remains unsolved whether CD320 is present in a soluble form (sCD320) in serum. Our aim...

Influence of scandium on the microstructure and mechanical properties of A319 alloy

International Nuclear Information System (INIS)

Emadi, Daryoush; Rao, A.K. Prasada; Mahfoud, Musbah

2010-01-01

Recycling of aluminum scrap alloys by melting is gaining its importance in foundry sector. During recycling, some of the alloying elements present in scrap alloys eventually become trace/tramp impurities in the recycled alloy. These elements could potentially affect the alloy's microstructure and hence its mechanical properties. In the present work, an attempt has been made to investigate the effect of one of such trace elements on the microstructure and mechanical properties of A319 alloy. The element chosen for the present investigation is scandium (Sc). This paper discusses the effects of the additions of trace amount of Sc on the microstructure and mechanical properties of A319 alloy in as-cast, T6 and T7 heat treated conditions.

75 FR 35 - Special Conditions: Airbus Model A318-112 Airplane (S/N 3886); Certification of a Cooktop

Science.gov (United States)

2010-01-04

... Recommended Practice 85, Rev. E, article titled, ``Air Conditioning Systems for Subsonic Airplanes,'' August 1...; Special Conditions No. 25-398-SC] Special Conditions: Airbus Model A318-112 Airplane (S/N 3886... airplane, as modified by Bizjet, a Lufthansa Technik Company, will have a novel or unusual design feature...

9 CFR 318.302 - Thermal processing.

Science.gov (United States)

2010-01-01

... 318.302 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Canning and Canned Products § 318.302 Thermal processing. (a) Process schedules. Prior to the processing...

7 CFR 318.13-22 - Bananas from Hawaii.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Bananas from Hawaii. 318.13-22 Section 318.13-22... SERVICE, DEPARTMENT OF AGRICULTURE STATE OF HAWAII AND TERRITORIES QUARANTINE NOTICES Regulated Articles From Hawaii and the Territories § 318.13-22 Bananas from Hawaii. (a) Green bananas (Musa spp.) of the...

49 CFR 238.319 - Running brake test.

Science.gov (United States)

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Running brake test. 238.319 Section 238.319... Requirements for Tier I Passenger Equipment § 238.319 Running brake test. (a) As soon as conditions safely permit, a running brake test shall be performed on each passenger train after the train has received, or...

31 CFR 537.318 - United States.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States. 537.318 Section 537.318 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF....318 United States. The term United States means the United States, its territories and possessions...

7 CFR 1205.319 - Cotton-producing region.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Cotton-producing region. 1205.319 Section 1205.319... Cotton Research and Promotion Order Definitions § 1205.319 Cotton-producing region. Cotton-producing region means each of the following groups of cotton-producing States: (a) Southeast Region: Alabama...

7 CFR 318.13-5 - Pest-free areas.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Pest-free areas. 318.13-5 Section 318.13-5 Agriculture... and the Territories § 318.13-5 Pest-free areas. Certain fruits or vegetables may be moved interstate provided that the fruits or vegetables originate from an area that is free of a specific pest or pests. In...

Constitutive Expression of a miR319 Gene Alters Plant Development and Enhances Salt and Drought Tolerance in Transgenic Creeping Bentgrass1[W][OA

Science.gov (United States)

Zhou, Man; Li, Dayong; Li, Zhigang; Hu, Qian; Yang, Chunhua; Zhu, Lihuang; Luo, Hong

2013-01-01

MicroRNA319 (miR319) is one of the first characterized and conserved microRNA families in plants and has been demonstrated to target TCP (for TEOSINTE BRANCHED/CYCLOIDEA/PROLIFERATING CELL FACTORS [PCF]) genes encoding plant-specific transcription factors. MiR319 expression is regulated by environmental stimuli, suggesting its involvement in plant stress response, although experimental evidence is lacking and the underlying mechanism remains elusive. This study investigates the role that miR319 plays in the plant response to abiotic stress using transgenic creeping bentgrass (Agrostis stolonifera) overexpressing a rice (Oryza sativa) miR319 gene, Osa-miR319a. We found that transgenic plants overexpressing Osa-miR319a displayed morphological changes and exhibited enhanced drought and salt tolerance associated with increased leaf wax content and water retention but reduced sodium uptake. Gene expression analysis indicated that at least four putative miR319 target genes, AsPCF5, AsPCF6, AsPCF8, and AsTCP14, and a homolog of the rice NAC domain gene AsNAC60 were down-regulated in transgenic plants. Our results demonstrate that miR319 controls plant responses to drought and salinity stress. The enhanced abiotic stress tolerance in transgenic plants is related to significant down-regulation of miR319 target genes, implying their potential for use in the development of novel molecular strategies to genetically engineer crop species for enhanced resistance to environmental stress. PMID:23292790

40 CFR 90.318 - Oxides of nitrogen analyzer calibration.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Oxides of nitrogen analyzer calibration. 90.318 Section 90.318 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Emission Test Equipment Provisions § 90.318 Oxides of nitrogen analyzer calibration. (a) Calibrate the...

40 CFR 91.318 - Oxides of nitrogen analyzer calibration.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Oxides of nitrogen analyzer calibration. 91.318 Section 91.318 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Provisions § 91.318 Oxides of nitrogen analyzer calibration. (a) Calibrate the chemiluminescent oxides of...

78 FR 71996 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2013-12-02

... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318-112, A319-111, A319-112, A319-115, A319-132, and A319-133 airplanes. This AD was... developing this AD. We have considered the comments received. Request To Refer to Revised EASA AD Airbus...

9 CFR 318.309 - Finished product inspection.

Science.gov (United States)

2010-01-01

... Section 318.309 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Canning and Canned Products § 318.309 Finished product inspection. (a) Finished product inspections must...

Project W-320, operational test procedure OTP-320-003 test report

International Nuclear Information System (INIS)

Bevins, R.R.

1998-01-01

This report documents and summarizes the results of OTP-320-003 Project W-320 Operational Testing of the WRSS Supernate Transfer System. Project W-320 Operational Test OTP-320-003 was performed to verify components of the Waste Retrieval Sluicing System (WRSS) supernate transfer system functioned as designed following construction completion and turnover to operations. All equipment operation was performed by Tank Farms Operations personnel following the operational test procedure and referenced operating procedures. Supernate Transfer line Flushing System Testing was completed over the course of approximately 4 weeks as tank farm conditions and configuration, equipment availability, and operations resources allowed. All testing was performed with the 702-AZ ventilation system and the 296-P-16 ventilation systems in operation. Test procedure OTP-320-003 required two revisions during testing to incorporate Procedure Changes Authorizations (PCAs) necessary to facilitate testing. Various sections of testing are documented on each procedure revision. The completed test procedure is included as Attachment A. Exception Reports generated during the course of testing are included as Attachment B

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3

Energy Technology Data Exchange (ETDEWEB)

Lu, Yinghao [Jiangsu Institute of Hematology, First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis Under Ministry of Health, Collaborative Innovation Center of Hematology, Suzhou, 215006 (China); Department of Hematology, Affiliated Hospital of Guizhou Medical University, The Hematopoietic Stem Cell Transplant Center of Guizhou Province, Blood Diseases Diagnosis and Treatment Center of Guizhou Province, Guiyang, 550004, Guizhou Province (China); Wu, Depei, E-mail: wudepei@medmail.com.cn [Jiangsu Institute of Hematology, First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis Under Ministry of Health, Collaborative Innovation Center of Hematology, Suzhou, 215006 (China); Wang, Jishi, E-mail: lgylhlyh@aliyun.com [Department of Hematology, Affiliated Hospital of Guizhou Medical University, The Hematopoietic Stem Cell Transplant Center of Guizhou Province, Blood Diseases Diagnosis and Treatment Center of Guizhou Province, Guiyang, 550004, Guizhou Province (China); Li, Yan; Chai, Xiao; Kang, Qian [Department of Hematology, Affiliated Hospital of Guizhou Medical University, The Hematopoietic Stem Cell Transplant Center of Guizhou Province, Blood Diseases Diagnosis and Treatment Center of Guizhou Province, Guiyang, 550004, Guizhou Province (China)

2016-05-13

Aberrant expression of microRNAs (miRNAs) is implicated in cancer development and progression. While miR-320a is reported to be deregulated in many malignancy types, its biological role in multiple myeloma (MM) remains unclear. Here, we observed reduced expression of miR-320a in MM samples and cell lines. Ectopic expression of miR-320a dramatically suppressed cell viability and clonogenicity and induced apoptosis in vitro. Mechanistic investigation led to the identification of Pre-B-cellleukemia transcription factor 3 (PBX3) as a novel and direct downstream target of miR-320a. Interestingly, reintroduction of PBX3 abrogated miR-320a-induced MM cell growth inhibition and apoptosis. In a mouse xenograft model, miR-320a overexpression inhibited tumorigenicity and promoted apoptosis. Our findings collectively indicate that miR-320a inhibits cell proliferation and induces apoptosis in MM cells by directly targeting PBX3, supporting its utility as a novel and potential therapeutic agent for miRNA-based MM therapy. -- Highlights: •Expression of miR-320a in MM cell induces apoptosis in vitro. •miR-320a represses PBX3 via targeting specific sequences in the 3′UTR region. •Exogenous expression of PBX3 reverses the effects of miR-320a in inhibiting MM cell growth and promoting apoptosis. •Overexpression of miR-320a inhibits tumor growth and increases apoptosis in vivo.

24 CFR 14.320 - Settlement.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Settlement. 14.320 Section 14.320... Applications § 14.320 Settlement. The applicant and agency counsel may agree on a proposed settlement of the award before final action on the application, either in connection with a settlement of the underlying...

7 CFR 318.13-25 - Sweet potatoes from Hawaii.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Sweet potatoes from Hawaii. 318.13-25 Section 318.13... INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE STATE OF HAWAII AND TERRITORIES QUARANTINE NOTICES Regulated Articles From Hawaii and the Territories § 318.13-25 Sweet potatoes from Hawaii. (a) Sweet potatoes may be...

29 CFR 99.320 - Report submission.

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Report submission. 99.320 Section 99.320 Labor Office of the Secretary of Labor AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 99.320... package pursuant to § 99.320(d)(2). (vii) A yes or no statement as to whether the auditee qualified as a...

Effects of Asn318 and Asp87Asn318 mutations on signal transduction by the gonadotropin-releasing hormone receptor and receptor regulation.

Science.gov (United States)

Awara, W M; Guo, C H; Conn, P M

1996-02-01

GnRH receptor (GnRH-R) contains Asn87 and Asp318 instead of the more frequently observed Asp87 and Asn318 found in other G protein-coupled receptors. In the present study, site-directed mutagenesis was used to introduce Asn318 and Asp87Asn318 into GnRH-R. The effect on coupling and regulation of GnRH-R was studied by stable expression of wild and mutant mouse GnRH-R in the lactotropic GH3 cells; these normally release PRL in response to TRH stimulation. The responses to Buserelin (a metabolically stable GnRH analog) in three different cell lines, M1, N8, and ND1 (expressing wild-type, Asn318 mutant, and Asp87Asn318 mutant mouse GnRH-R, respectively) were compared with that observed in the previously characterized GGH3-1' cells, which stably express rat GnRH-R. The Asn318 and Asp87Asn318 mutations had no measurable effect on ligand binding, but abolished the initial down-regulation of receptor that was observed in M1 and GGH3-1' cells, suggesting that the normal location of Asn87 and Asp318 in GnRH-R is involved in the regulation of GnRH-R. In N8 and ND1 cells, Buserelin-stimulated inositol phosphate (IP) production was attenuated, but the release of both cAMP and PRL was stimulated in a dose- and time-dependent manner. These mutations apparently impaired the coupling between GnRH-R and G proteins involved in IP production, but not those involved in cAMP release. In M1 cells, Buserelin stimulation produced a significant increase in IP production, but neither cAMP nor PRL release was significantly stimulated. These findings are consistent with the previous suggestion that GnRH-stimulated PRL release is mediated by a cAMP second messenger system in transfected GGH3 cells.

9 CFR 318.301 - Containers and closures.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Containers and closures. 318.301... Canning and Canned Products § 318.301 Containers and closures. (a) Examination and cleaning of empty containers. (1) Empty containers, closures, and flexible pouch roll stock shall be evaluated by the...

42 CFR 486.318 - Condition: Outcome measures.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Outcome measures. 486.318 Section 486... Organizations Organ Procurement Organization Outcome Requirements § 486.318 Condition: Outcome measures. (a..., territories, or possessions, an OPO must meet all 3 of the following outcome measures: (1) The OPO's donation...

26 CFR 1.318-3 - Estates, trusts, and options.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Estates, trusts, and options. 1.318-3 Section 1... (CONTINUED) INCOME TAXES Definitions; Constructive Ownership of Stock § 1.318-3 Estates, trusts, and options... illustrating the use of these factors and methods. (c) The application of section 318(a) relating to options...

7 CFR 318.13-23 - Cut flowers from Hawaii.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Cut flowers from Hawaii. 318.13-23 Section 318.13-23... SERVICE, DEPARTMENT OF AGRICULTURE STATE OF HAWAII AND TERRITORIES QUARANTINE NOTICES Regulated Articles From Hawaii and the Territories § 318.13-23 Cut flowers from Hawaii. (a) Except for cut blooms and leis...

7 CFR 318.13-17 - Regulated articles from Guam.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Regulated articles from Guam. 318.13-17 Section 318.13... Articles From Hawaii and the Territories § 318.13-17 Regulated articles from Guam. (a)(1) Regulated articles, other than soil, may be moved from Guam into or through any other State only if they meet the...

75 FR 11439 - Airworthiness Directives; Airbus Model A319, A320, and A321 Series Airplanes

Science.gov (United States)

2010-03-11

... the needle colour and thickness and an increase in width of the TCAS green band. For the reasons... the erasable programmable read only memory (EPROM) (for certain configurations) in addition to... the case of TCAS Resolution Advisory. This modification consists of a change in the needle colour and...

7 CFR 319.40-6 - Universal importation options.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Universal importation options. 319.40-6 Section 319.40-6 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH... Unmanufactured Wood Articles § 319.40-6 Universal importation options. (a) Logs. Logs may be imported if prior to...

7 CFR 319.37-10 - Marking and identity.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Marking and identity. 319.37-10 Section 319.37-10 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION..., and Other Plant Products 1,2 § 319.37-10 Marking and identity. (a) Any restricted article for...

21 CFR 320.27 - Guidelines on the design of a multiple-dose in vivo bioavailability study.

Science.gov (United States)

2010-04-01

... vivo bioavailability study. 320.27 Section 320.27 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE BIOAVAILABILITY AND BIOEQUIVALENCE REQUIREMENTS Procedures for Determining the Bioavailability or Bioequivalence of Drug Products § 320.27...

9 CFR 318.304 - Operations in the thermal processing area.

Science.gov (United States)

2010-01-01

... area. 318.304 Section 318.304 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION... PREPARATION OF PRODUCTS Canning and Canned Products § 318.304 Operations in the thermal processing area. (a...

7 CFR 319.73-4 - Costs.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Costs. 319.73-4 Section 319.73-4 Agriculture..., DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Coffee § 319.73-4 Costs. All costs of inspection... duty will be furnished without cost to the importer. ...

A Laboratory Study of the Effect of Stress State on the Elastic Moduli of Sand

Science.gov (United States)

1990-01-01

frequency. Drnevich (1967) investigated the effect of strain history on the dynamic properties of a dry Ottawa sand. One finding of his work was that the...2.2) in which jo = effective octahedral normal stress, e = void ratio, H = ambient stress and vibration history , S - de9,ee of saturation, To...zt) = ik[Cei(kz-wt) - De-i(kz+Wt) (3.20) dz I Substituting Eqs. 3.19 and 3.20 into the second boundary condition at z - L yields ikEA [Cei(kL-cot

24 CFR 320.15 - Default.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Default. 320.15 Section 320.15... SECURITIES Pass-Through Type Securities § 320.15 Default. (a) Issuer default. Any failure or inability of the... default of the issuer. (b) Action upon default. Upon any default by the issuer, the Association may: (1...

10 CFR 2.320 - Default.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Default. 2.320 Section 2.320 Energy NUCLEAR REGULATORY COMMISSION RULES OF PRACTICE FOR DOMESTIC LICENSING PROCEEDINGS AND ISSUANCE OF ORDERS Rules of General... § 2.320 Default. If a party fails to file an answer or pleading within the time prescribed in this...

31 CFR 575.319 - United States.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States. 575.319 Section 575.319 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF....319 United States. The term United States means the United States, its territories and possessions...

7 CFR 319.56-5 - Pest-free areas.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Pest-free areas. 319.56-5 Section 319.56-5 Agriculture..., DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Fruits and Vegetables § 319.56-5 Pest-free areas. As... provided that the fruits or vegetables originate from an area that is free of a specific pest or pests. In...

7 CFR 319.8-23 - Treatment.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Treatment. 319.8-23 Section 319.8-23 Agriculture....8-23 Treatment. (a)(1) Vacuum fumigation as required in this subpart shall consist of fumigation, in... the substitution of processing, utilization, or other form of treatment for vacuum fumigation when in...

9 CFR 318.307 - Record review and maintenance.

Science.gov (United States)

2010-01-01

... Section 318.307 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Canning and Canned Products § 318.307 Record review and maintenance. (a) Process records. Charts from...

7 CFR 319.24a - Administrative instructions relating to entry of corn into Guam.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Administrative instructions relating to entry of corn...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Corn Diseases Quarantine § 319.24a Administrative instructions relating to entry of corn into Guam. Corn may be...

46 CFR 182.320 - Water heaters.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Water heaters. 182.320 Section 182.320 Shipping COAST...) MACHINERY INSTALLATION Auxiliary Machinery § 182.320 Water heaters. (a) A water heater must meet the...), except that an electric water heater is also acceptable if it: (1) Has a capacity of not more than 454...

9 CFR 319.80 - Barbecued meats.

Science.gov (United States)

2010-01-01

... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Cooked Meats § 319.80 Barbecued meats. Barbecued meats, such as product labeled “Beef Barbecue” or “Barbecued Pork,” shall be cooked by the direct... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Barbecued meats. 319.80 Section 319.80...

A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol

Science.gov (United States)

2009-01-01

Background L-arabitol dehydrogenase (LAD) and xylitol dehydrogenase (XDH) are involved in the degradation of L-arabinose and D-xylose, which are among the most abundant monosaccharides on earth. Previous data demonstrated that LAD and XDH not only differ in the activity on their biological substrate, but also that only XDH has significant activity on D-sorbitol and may therefore be more closely related to D-sorbitol dehydrogenases (SDH). In this study we aimed to identify residues involved in the difference in substrate specificity. Results Phylogenetic analysis demonstrated that LAD, XDH and SDH form 3 distinct groups of the family of dehydrogenases containing an Alcohol dehydrogenase GroES-like domain (pfam08240) and likely have evolved from a common ancestor. Modelling of LadA and XdhA of the saprobic fungus Aspergillus niger on human SDH identified two residues in LadA (M70 and Y318), that may explain the absence of activity on D-sorbitol. While introduction of the mutation M70F in LadA of A. niger resulted in a nearly complete enzyme inactivation, the Y318F resulted in increased activity for L-arabitol and xylitol. Moreover, the affinity for D-sorbitol was increased in this mutant. Conclusion These data demonstrates that Y318 of LadA contributes significantly to the substrate specificity difference between LAD and XDH/SDH. PMID:19674460

46 CFR 119.320 - Water heaters.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Water heaters. 119.320 Section 119.320 Shipping COAST... Machinery § 119.320 Water heaters. (a) A water heater must meet the requirements of Parts 53 and 63 in... electric water heater is also acceptable if it: (1) Has a capacity of not more than 454 liters (120 gallons...

9 CFR 319.701 - Mixed fat shortening.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Mixed fat shortening. 319.701 Section... § 319.701 Mixed fat shortening. Shortening prepared with a mixture of meat fats and vegetable oils may... descending order of predominance. ...

42 CFR 403.318 - Approval of State systems.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Approval of State systems. 403.318 Section 403.318 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS Recognition of State Reimbursement Control Systems § 403.318...

20 CFR 30.320 - Can a claim be reopened after the FAB has issued a final decision?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Can a claim be reopened after the FAB has... AMENDED Adjudicatory Process Reopening Claims § 30.320 Can a claim be reopened after the FAB has issued a final decision? (a) At any time after the FAB has issued a final decision pursuant to § 30.316, and...

7 CFR 1205.320 - Marketing year.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Marketing year. 1205.320 Section 1205.320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.320 Marketing year. Marketing year means a consecutive 12...

25 CFR 11.318 - Extradition.

Science.gov (United States)

2010-04-01

... Criminal Procedure § 11.318 Extradition. Any Court of Indian Offenses may order delivery to the proper..., the accused shall be accorded a right to contest the propriety of the court's order in a hearing...

31 CFR 586.318 - United States.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States. 586.318 Section 586...) KOSOVO SANCTIONS REGULATIONS General Definitions § 586.318 United States. The term United States means the United States, its territories and possessions, and all areas under the jurisdiction or authority...

31 CFR 597.318 - United States.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States. 597.318 Section 597... General Definitions § 597.318 United States. The term United States means the United States, its territories, states, commonwealths, districts, and possessions, and all areas under the jurisdiction or...

7 CFR 319.75-6 - Arrival notification.

Science.gov (United States)

2010-01-01

... Plant Protection and Quarantine of the arrival by such means as a manifest, Customs entry document... 7 Agriculture 5 2010-01-01 2010-01-01 false Arrival notification. 319.75-6 Section 319.75-6 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

Relationships Between Solidification Parameters in A319 Aluminum Alloy

Science.gov (United States)

Vandersluis, E.; Ravindran, C.

2018-03-01

The design of high-performance materials depends on a comprehensive understanding of the alloy-specific relationships between solidification and properties. However, the inconsistent use of a particular solidification parameter for presenting materials characterization in the literature impedes inter-study comparability and the interpretation of findings. Therefore, there is a need for accurate expressions relating the solidification parameters for each alloy. In this study, A319 aluminum alloy castings were produced in a permanent mold with various preheating temperatures in order to control metal cooling. Analysis of the cooling curve for each casting enabled the identification of its liquidus, Al-Si eutectic, and solidus temperatures and times. These values led to the calculation of the primary solidification rate, total solidification rate, primary solidification time, and local solidification time for each casting, which were related to each other as well as to the average casting SDAS and material hardness. Expressions for each of their correlations have been presented with high coefficients of determination, which will aid in microstructural prediction and casting design.

14 CFR 152.319 - Monitoring and reporting of program performance.

Science.gov (United States)

2010-01-01

... performance. 152.319 Section 152.319 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Accounting and Reporting Requirements § 152.319 Monitoring and reporting of program performance. (a) The sponsor or planning agency shall monitor performance...

A 320 mV, 6 kb subthreshold 10T SRAM employing voltage lowering techniques

International Nuclear Information System (INIS)

Cai Jiangzheng; Zhang Sumin; Yuan Jia; Shang Xinchao; Chen Liming; Hei Yong

2015-01-01

This paper presents a 6 kb SRAM that uses a novel 10T cell to achieve a minimum operating voltage of 320 mV in a 130 nm CMOS process. A number of low power circuit techniques are included to enable the proposed SRAM to operate in the subthreshold region. The reverse short channel effect and the reverse narrow channel effect are utilized to improve the performance of the SRAM. A novel subthreshold pulse generation circuit produces an ideal pulse to make read operation stable. A floating write bit-line effectively reduces the standby leakage consumption. Finally, a short read bit-line makes the read operation fast and energy-saving. Measurements indicate that these techniques are effective, the SRAM can operate at 800 kHz and consume 1.94 μW at its lowest voltage (320 mV). (paper)

7 CFR 319.37-11 - Arrival notification.

Science.gov (United States)

2010-01-01

... article at a port of entry, the importer shall notify the Plant Protection and Quarantine Programs of the... 7 Agriculture 5 2010-01-01 2010-01-01 false Arrival notification. 319.37-11 Section 319.37-11 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

32 CFR 318.2 - Applicability.

Science.gov (United States)

2010-07-01

... locations. (b) This part shall be made applicable to DoD contractors who are operating a system of records... DEFENSE THREAT REDUCTION AGENCY PRIVACY PROGRAM § 318.2 Applicability. (a) This part applies to all..., associated with maintaining a system of records. ...

Albumin Redhill (-1 Arg, 320 Ala → Thr): A glycoprotein variant of human serum albumin whose precursor has an aberrant signal peptidase cleavage site

International Nuclear Information System (INIS)

Brennan, S.O.; Myles, T.; Peach, R.J.; George, P.M.; Donaldson, D.

1990-01-01

Albumin Redhill is an electrophoretically slow genetic variant of human serum albumin that does not bind 63 Ni 2+ and has a molecular mass 2.5 kDa higher than normal albumin. Its inability to bind Ni 2+ was explained by the finding of an additional residue of Arg at position -1. This did not explain the molecular basis of the genetic variation or the increase in apparent molecular mass. Fractionation of tryptic digests on concanavalin A-Sepharose followed by peptide mapping of the bound and unbound fractions and sequence analysis of the glycopeptides identified a mutation of 320 Ala → Thr. This introduces as Asn-Tyr-Thr oligosaccharide attachment sequence centered on Asn-318 and explains the increase in molecular mass. This, however, did not satisfactorily explain the presence of the additional Arg residue at position -1. DNA sequencing of polymerase chain reaction-amplified genomic DNA encoding the prepro sequence of albumin indicated an additional mutation of -2 Arg → Cys. The authors propose that the new Phe-Cys-Arg sequence in the propeptide is an aberrant signal peptidase cleavage site and that the signal peptidase cleaves the propeptide of albumin Redhill in the lumen of the endoplasmic reticulum before it reaches the Golgi vesicles, the site of the diarginyl-specific proalbumin convertase

New possibilities of using A-319CJ aircraft at the Czech Air Force

Directory of Open Access Journals (Sweden)

Miroslav JANOŠEK

2011-01-01

Full Text Available The article analyses remarkable changes in activities of the transport airbase in terms of substitution of obsolete aircraft by modern transport airplanes. Further, differences between transport airbase’s aircraft and Czech Airlines’ airplanes are introduced, as well as fundamental tactical and operating specifications, time and space factors regarding personnel transport, supplies transport and possibilities of Airbus A319CJ’s freight hold adjustment in dependence on the nature of transport.

32 CFR 644.319 - Protection of wetlands.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Protection of wetlands. 644.319 Section 644.319... ESTATE HANDBOOK Disposal § 644.319 Protection of wetlands. The requirements of Executive Order 11990, Protection of Wetlands, 42 FR 26961, (24 May 1977) are applicable to the disposal of Federal lands and...

320-row CT coronary angiography predicts freedom from revascularisation and acts as a gatekeeper to defer invasive angiography in stable coronary artery disease: a fractional flow reserve-correlated study

International Nuclear Information System (INIS)

Ko, Brian S.; Wong, Dennis T.L.; Cameron, James D.; Leung, Michael; Meredith, Ian T.; Nerlekar, Nitesh; Antonis, Paul; Harper, Richard; Malaiapan, Yuvaraj; Seneviratne, Sujith K.; Leong, Darryl P.; Crossett, Marcus; Troupis, John

2014-01-01

To determine the accuracy of 320-row multidetector coronary computed tomography angiography (M320-CCTA) to detect functional stenoses using fractional flow reserve (FFR) as the reference standard and to predict revascularisation in stable coronary artery disease. One hundred and fifteen patients (230 vessels) underwent M320-CCTA and FFR assessment and were followed for 18 months. Diameter stenosis on invasive angiography (ICA) and M320-CCTA were assessed by consensus by two observers and significant stenosis was defined as ≥50 %. FFR ≤0.8 indicated functionally significant stenoses. M320-CCTA had 94 % sensitivity and 94 % negative predictive value (NPV) for FFR ≤0.8. Overall accuracy was 70 %, specificity 54 % and positive predictive value 65 %. On receiver operating characteristic (ROC) curve analysis, the area under the curve (AUC) for CCTA to predict FFR ≤0.8 was 0.74 which was comparable with ICA. The absence of a significant stenosis on M320-CCTA was associated with a 6 % revascularisation rate. M320-CCTA predicted revascularisation with an AUC of 0.71 which was comparable with ICA. M320-CCTA has excellent sensitivity and NPV for functional stenoses and therefore may act as an effective gatekeeper to defer ICA and revascularisation. Like ICA, M320-CCTA lacks specificity for functional stenoses and only has moderate accuracy to predict the need for revascularisation. (orig.)

76 FR 67625 - Airworthiness Directives; Airbus Model A319 and A320 Series Airplanes

Science.gov (United States)

2011-11-02

... exits being unserviceable which, during an emergency, would impair the safe evacuation of occupants... comments. Fax: (202) 493-2251. Mail: U.S. Department of Transportation, Docket Operations, M-30, West.... Department of Transportation, Docket Operations, M-30, West Building Ground Floor, Room W12-140, 1200 New...

Airbus A320 NEO Base Maintenance Concept SAS Operations

OpenAIRE

Dafgård, Oscar

2017-01-01

Detta arbete har utförts tillsammans med SAS, för att undersöka om ett base maintenance koncept med ett intervall på 36 månader skulle vara mer kostnadseffektivt än 24 månader för deras nya Airbus A320 NEO flotta. SAS, precis som alla andra flygbolag utnyttjar sina flygplan på sina egna och specifika vis. Eftersom inga flygbolag opererar på samma sätt kan inte heller underhållet skötas på samma sätt för en specifik flygplanstyp. Underhållsprogrammet behövde därför ses över för att optimeras g...

Proposal to endorse the award of a contract for the supply of a juniper T320 network router

CERN Document Server

2003-01-01

This document concerns the award of a contract for the supply of a JUNIPER T320 Network Router. The Finance Committee is invited to endorse the CERN Management's decision to negotiate a contract with QWEST COMMUNICATION (USA) for the supply of a JUNIPER T320 Network Router for a total amount not exceeding 265 000 US dollars (350 000 Swiss francs). The Finance Committee is also requested to approve the negotiation of a maintenance contract for a value not exceeding 50 000 US dollars (66 000 Swiss francs) for three years and the option to purchase additional network interfaces for a value not exceeding 100 000 US dollars (132 000 Swiss francs) bringing the total amount to 415 000 US dollars (548 000 Swiss francs), not subject to revision. CERN's contribution will not exceed 90 000 Swiss francs. The amounts in Swiss francs have been calculated using the present rate of exchange. The firm has indicated the following distribution by country of the contract value covered by this adjudication proposal: CA - 100%.

9 CFR 319.308 - Tripe with milk.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Tripe with milk. 319.308 Section 319... Products § 319.308 Tripe with milk. “Tripe with Milk” shall be prepared so that the finished canned article, exclusive of the cooked-out juices and milk, will contain at least 65 percent tripe. The product shall be...

46 CFR 183.320 - Generators and motors.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Generators and motors. 183.320 Section 183.320 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.320 Generators and motors. (a) Each generator and motor must be: (1) In a location that is accessible, adequately ventilated, and as dry as...

9 CFR 318.310 - Personnel and training.

Science.gov (United States)

2010-01-01

... Section 318.310 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Canning and Canned Products § 318.310 Personnel and training. All operators of thermal processing systems...

7 CFR 319.55-7 - Importations by mail.

Science.gov (United States)

2010-01-01

... foreign mailing point by a special mailing tag directing the package to a Plant Protection and Quarantine... 7 Agriculture 5 2010-01-01 2010-01-01 false Importations by mail. 319.55-7 Section 319.55-7 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

7 CFR 319.56-1 - Notice of quarantine.

Science.gov (United States)

2010-01-01

... quarantine. (a) Under section 412(a) of the Plant Protection Act, the Secretary of Agriculture may prohibit... 7 Agriculture 5 2010-01-01 2010-01-01 false Notice of quarantine. 319.56-1 Section 319.56-1 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

7 CFR 319.8-4 - Notice of arrival.

Science.gov (United States)

2010-01-01

... for the Plant Protection and Quarantine Programs, a notice of such arrival, on a form provided for... 7 Agriculture 5 2010-01-01 2010-01-01 false Notice of arrival. 319.8-4 Section 319.8-4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

7 CFR 319.56-41 - Citrus from Peru.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Citrus from Peru. 319.56-41 Section 319.56-41... from Peru. Grapefruit (Citrus paradisi), limes (C. aurantiifolia), mandarins or tangerines (C... States from Peru under the following conditions: (a) The fruit must be accompanied by a permit issued in...

Determination of a novel integron-located variant (blaOXA -320 ) of Class D β-lactamase in Proteus mirabilis.

Science.gov (United States)

Cicek, Aysegul Copur; Duzgun, Azer Ozad; Saral, Aysegul; Sandalli, Cemal

2014-10-01

Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. The isolate was identified using the API 32GN system and 16S rRNA gene sequencing and it was found resistant to ampicillin/sulbactam, piperacillin, tetracycline, and trimethoprim/sulfamethoxazole. This isolate was harboring a Class 1 integron gene cassette and its DNA sequence analysis revealed a novel blaOXA variant exhibiting one amino acid substitution (Asn266Ile) from blaOXA-1 . This new variant of OXA was located on Class 1 integron together with aadA1 gene encoding aminoglycoside-modifying enzymes. According to sequence records, the new variant was named as blaOXA-320 . Cassette array and size of integron were found as blaOXA-320 -aadA1 and 2086 bp, respectively. The blaOXA-320 gene is not transferable according to conjugation experiment. In this study, we report the first identification of blaOXA-320 -aadA1 gene cassette, a novel variant of Class D β-lactamase, in P. mirabilis from Turkey. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

46 CFR 132.320 - Helicopter-landing decks.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Helicopter-landing decks. 132.320 Section 132.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS FIRE-PROTECTION EQUIPMENT Miscellaneous § 132.320 Helicopter-landing decks. Each vessel with a helicopter-landing deck must...

7 CFR 319.8-9 - Hull fiber and gin trash.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Hull fiber and gin trash. 319.8-9 Section 319.8-9 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION... Importation and Entry of Cotton and Covers § 319.8-9 Hull fiber and gin trash. (a) Entry of hull fiber will be...

7 CFR 319.41-6 - Importations by mail.

Science.gov (United States)

2010-01-01

... the package to a Plant Protection and Quarantine Programs inspection station for inspection in... 7 Agriculture 5 2010-01-01 2010-01-01 false Importations by mail. 319.41-6 Section 319.41-6 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

Spinning-Up: the Case of the Symbiotic X-Ray Binary 3A 1954+319

Science.gov (United States)

Fuerst, F.; Marcu, D. M.; Pottschmidt, K.; Grinberg, V.; Wilms, J.; CadolleBel, M.

2011-01-01

We present a timing and spectral analysis of the variable X-ray source 3A 1954+319. Our analysis is mainly based on an outburst serendipitously observed during INTEGRAL Key Program observations of the Cygnus region in 2008 fall and on the Swift/BAT longterm light curve. Previous observations, though sparse, have identified the source to be one of only nine known symbiotic X-ray binaries, i.e., systems composed of an accreting neutron star orbiting in a highly inhomogeneous medium around an M-giant companion. The spectrum of3A 1954+319 above > 20 keV can be best described by a broken power law model. The extremely long pulse period of approx.5.3 hours is clearly visible in the INTEGRAL/ISGRI light curve and confirmed through an epoch folding period search. Furthermore, the light curve allows us to determine a very strong spin up of -2 x 10(exp -4) h/h during the outburst. This spin up is confirmed by the pulse period evolution calculated from Swift/BAT data. The Swift/BAT data also show a long spin-down trend prior to the 2008 outburst, which is confirmed in archival INTEGRAL/ISGRI data. We discuss possible accretion models and geometries allowing for the transfer of such large amounts of angular momentum and investigate the harder spectrum of this outburst compared to previously published results.

24 CFR 5.318 - Discretionary pet rules.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discretionary pet rules. 5.318 Section 5.318 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Pet Ownership for the Elderly or Persons With...

Optimization of Coolant Technique Conditions for Machining A319 Aluminium Alloy Using Response Surface Method (RSM)

Science.gov (United States)

Zainal Ariffin, S.; Razlan, A.; Ali, M. Mohd; Efendee, A. M.; Rahman, M. M.

2018-03-01

Background/Objectives: The paper discusses about the optimum cutting parameters with coolant techniques condition (1.0 mm nozzle orifice, wet and dry) to optimize surface roughness, temperature and tool wear in the machining process based on the selected setting parameters. The selected cutting parameters for this study were the cutting speed, feed rate, depth of cut and coolant techniques condition. Methods/Statistical Analysis Experiments were conducted and investigated based on Design of Experiment (DOE) with Response Surface Method. The research of the aggressive machining process on aluminum alloy (A319) for automotive applications is an effort to understand the machining concept, which widely used in a variety of manufacturing industries especially in the automotive industry. Findings: The results show that the dominant failure mode is the surface roughness, temperature and tool wear when using 1.0 mm nozzle orifice, increases during machining and also can be alternative minimize built up edge of the A319. The exploration for surface roughness, productivity and the optimization of cutting speed in the technical and commercial aspects of the manufacturing processes of A319 are discussed in automotive components industries for further work Applications/Improvements: The research result also beneficial in minimizing the costs incurred and improving productivity of manufacturing firms. According to the mathematical model and equations, generated by CCD based RSM, experiments were performed and cutting coolant condition technique using size nozzle can reduces tool wear, surface roughness and temperature was obtained. Results have been analyzed and optimization has been carried out for selecting cutting parameters, shows that the effectiveness and efficiency of the system can be identified and helps to solve potential problems.

Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1

NARCIS (Netherlands)

Nielsen, Peter A; Beahm, Derek L; Giepmans, Ben N G; Baruch, Amos; Hall, James E; Kumar, Nalin M

2002-01-01

A novel human connexin gene (GJA11) was cloned from a genomic library. The open reading frame encoded a hypothetical protein of 294 amino acid residues with a predicted molecular mass of 31,933, hence referred to as connexin-31.9 (Cx31.9) or alpha 11 connexin. A clone in GenBank containing the

7 CFR 1493.320 - Recovery of losses.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Recovery of losses. 1493.320 Section 1493.320... Facility Guarantee Program (FGP) Operations § 1493.320 Recovery of losses. (a) Notification. Upon payment of loss to the exporter or the exporter's assignee, CCC will notify the foreign bank of CCC's rights...

7 CFR 319.8-11 - From approved areas of Mexico.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false From approved areas of Mexico. 319.8-11 Section 319.8... Conditions for the Entry of Cotton and Covers from Mexico § 319.8-11 From approved areas of Mexico. (a) Entry... in, and which were produced and handled only in approved areas of Mexico 5 may be authorized through...

7 CFR 319.75-5 - Marking and identity.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Marking and identity. 319.75-5 Section 319.75-5 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION... identity. (a) Any restricted article at the time of importation shall plainly and correctly bear on the...

7 CFR 319.69-2 - Freedom from pests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Freedom from pests. 319.69-2 Section 319.69-2 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION... § 319.69-2 Freedom from pests. All packing materials allowed entry under restriction shall be free from...

7 CFR 319.75-2 - Restricted articles. 1

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Restricted articles. 1 319.75-2 Section 319.75-2... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Khapra Beetle § 319.75-2 Restricted articles. 1 1 The importation of restricted articles may be subject to prohibitions or restrictions under...

24 CFR 320.31 - Default.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Default. 320.31 Section 320.31 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT... SECURITIES Bond-Type Securities § 320.31 Default. Upon default of the issuer, the Association has the right...

46 CFR 120.320 - Generators and motors.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Generators and motors. 120.320 Section 120.320 Shipping... and Distribution Systems § 120.320 Generators and motors. (a) Each generator and motor must be: (1) In... generator and motor must be designed for an ambient temperature of 50 °C (122 °F) except that: (1) If the...

9 CFR 319.261 - Meat loaf.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Meat loaf. 319.261 Section 319.261... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Luncheon Meat, Loaves and Jellied Products...

9 CFR 319.500 - Meat pies.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Meat pies. 319.500 Section 319.500... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Food Entree Products, Pies, and...

9 CFR 319.304 - Meat stews.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Meat stews. 319.304 Section 319.304... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Canned, Frozen, or Dehydrated Meat Food...

9 CFR 319.260 - Luncheon meat.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Luncheon meat. 319.260 Section 319.260... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Luncheon Meat, Loaves and Jellied Products...

7 CFR 319.56-31 - Peppers from Spain.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Peppers from Spain. 319.56-31 Section 319.56-31... from Spain. Peppers (fruit) (Capsicum spp.) may be imported into the United States from Spain only... subpart: (a) The peppers must be grown in the Alicante or Almeria Province of Spain in pest-proof...

7 CFR 319.8-13 - From Northwest Mexico.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false From Northwest Mexico. 319.8-13 Section 319.8-13... for the Entry of Cotton and Covers from Mexico § 319.8-13 From Northwest Mexico. Contingent upon continued freedom of Northwest Mexico and of the West Coast of Mexico from infestations of the pink bollworm...

Energy efficiency improvements in air traffic: The case of Airbus A320 in Spain

International Nuclear Information System (INIS)

Cansino, José M.; Román, Rocío

2017-01-01

Structural improvements in aircraft design, seeking to improve energy efficiency, can significantly reduce greenhouse gas emissions (GHG) by reducing reduced fuel consumption. This research reviews improvements with the introduction of a structural component known as 'winglet;' these are positioned at the top of the aircraft wing, and increased Airbus Group A320 sales. Data used are taken from air traffic in Spain for the 2010–2014 period with projections being made for 2020. The results show that winglets reduce CO_2 equivalent emissions associated with Spain's air transport for the 2015–2020 period between 66.29 and 59.56 Gg. depending on the scenario considered in 2020. - Highlights: • Spanish air traffic is considered a key-GHG emission sector. • The aviation industry has drastically reduced its emissions. • To what extent could improved model to reduce fuel consumption and polluting emissions? • A320 Neo, A330 Neo and A380 Neo models are in the process of industrialisation. • Objectives fixed by Air Transport Action Group for 2020 are relevant.

27 CFR 24.320 - Chemical record.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Chemical record. 24.320... OF THE TREASURY LIQUORS WINE Records and Reports § 24.320 Chemical record. A proprietor who uses chemicals, preservatives, or other such materials shall maintain a record of the purchase, receipt and...

9 CFR 318.306 - Processing and production records.

Science.gov (United States)

2010-01-01

....306 Section 318.306 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Canning and Canned Products § 318.306 Processing and production records. At least the following processing...

7 CFR 318.13-24 - Sweet potatoes from Puerto Rico.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Sweet potatoes from Puerto Rico. 318.13-24 Section 318... Articles From Hawaii and the Territories § 318.13-24 Sweet potatoes from Puerto Rico. Sweet potatoes from Puerto Rico may be moved interstate to Atlantic Coast ports north of and including Baltimore, MD, under...

7 CFR 318.13-21 - Avocados from Hawaii to Alaska.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Avocados from Hawaii to Alaska. 318.13-21 Section 318... Articles From Hawaii and the Territories § 318.13-21 Avocados from Hawaii to Alaska. Avocados may be moved... marking requirements. The avocados may be moved interstate for distribution in Alaska only, the boxes of...

17 CFR 31.8 - Cover of leverage contracts.

Science.gov (United States)

2010-04-01

... receipt for two business days: Provided, however, That the amount of physical commodities subject to such... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Cover of leverage contracts. 31.8 Section 31.8 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION LEVERAGE...

Discovery and introduction of a (3,18)-connected net as an ideal blueprint for the design of metal-organic frameworks

KAUST Repository

Guillerm, Vincent; Weselinski, Lukasz Jan; Belmabkhout, Youssef; Cairns, Amy; D'Elia, Valerio; Wojtas, Łukasz; Adil, Karim; Eddaoudi, Mohamed

2014-01-01

-organic polyhedra act as supermolecular building blocks when they form gea-MOF-2. The discovery of a (3,18)-connected MOF followed by deliberate transposition of its topology to a predesigned second MOF with a different chemical system validates the prospective

31 CFR 515.320 - Domestic bank.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Domestic bank. 515.320 Section 515... § 515.320 Domestic bank. The term domestic bank shall mean any branch or office within the United States of any of the following which is not a national of a designated foreign country; any bank or trust...

24 CFR 583.320 - Site control.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Site control. 583.320 Section 583... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Program Requirements § 583.320 Site control. (a) Site control. (1) Where grant funds will be used for acquisition, rehabilitation, or new construction...

31 CFR 538.319 - U.S. registered money transmitter.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. registered money transmitter. 538.319 Section 538.319 Money and Finance: Treasury Regulations Relating to Money and Finance... General Definitions § 538.319 U.S. registered money transmitter. The term U.S. registered money...

31 CFR 585.318 - U.S. financial institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. financial institution. 585.318... General Definitions § 585.318 U.S. financial institution. The term U.S. financial institution means any U... foregoing. This term includes those branches, offices and agencies of foreign financial institutions which...

38 CFR 3.318 - Presumptive service connection for amyotrophic lateral sclerosis.

Science.gov (United States)

2010-07-01

... connection for amyotrophic lateral sclerosis. 3.318 Section 3.318 Pensions, Bonuses, and Veterans' Relief... sclerosis. (a) Except as provided in paragraph (b) of this section, the development of amyotrophic lateral... under this section: (1) If there is affirmative evidence that amyotrophic lateral sclerosis was not...

7 CFR 319.56-39 - Fragrant pears from China.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Fragrant pears from China. 319.56-39 Section 319.56-39... pears from China. Fragrant pears may be imported into the United States from China only under the... China. (2) All propagative material introduced into a registered production site must be certified free...

9 CFR 318.305 - Equipment and procedures for heat processing systems.

Science.gov (United States)

2010-01-01

... processing systems. 318.305 Section 318.305 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION... PREPARATION OF PRODUCTS Canning and Canned Products § 318.305 Equipment and procedures for heat processing...

Cyclo-octafluorobutane (PFC-318) in the global atmosphere

Science.gov (United States)

Muhle, J.; Vollmer, M. K.; Fraser, P. J.; Rhee, T. S.; Ivy, D. J.; Arnold, T.; Harth, C. M.; Salameh, P.; O'Doherty, S.; Young, D.; Steele, P.; Krummel, P. B.; Leist, M.; Schmidbauer, N.; Lunder, C.; Kim, J.; Kim, K.; Reimann, S.; Simmonds, P.; Prinn, R. G.; Weiss, R. F.

2010-12-01

PFC-318 (c-C4F8, cyclo-octafluorobutane) is a long-lived (3200 years) perfluorocarbon (PFC) greenhouse gas with a high 100-year Global Warming Potential (GWP100 = 10,300) and a wide range of industrial uses. We extend previous atmospheric measurements of PFC-318 in the Cape Grim Air Archive (Oram, 1999) with our new in situ measurements from remote and urban AGAGE (Advanced Global Atmospheric Gases Experiment) and affiliated stations. Our longest in situ record is from the Jungfraujoch observatory in the Swiss Alps, and our data set is augmented by measurements of flasks from the King Sejong and Troll coastal Antarctic stations and several locations in the Northern Hemisphere. In mid-2009 we find ˜1.25 ppt (parts-per-trillion, dry mol fraction) in the Northern Hemisphere and ˜1.20 ppt in the Southern Hemisphere, with rise rates of ˜0.03 ppt/yr and an interhemispheric ratio of ˜1.04. We obtain PFC-318 emissions for 2008-2010 of ˜1 Gg/yr using a simple box model, and preliminary measurements of older archived air at SIO indicate similar emissions since at the least the late 1990s. In contrast, the EDGAR v4 emissions database estimates much lower PFC-318 emissions of 0.02 Gg/yr for 2005. Using GWP100 we calculate ˜10 million tons of CO2-equivalent PFC-318 emissions/yr for 2008-2010, about double the CO2-equivalent PFC-218 annual emissions, or 0.4 times the CO2-equivalent PFC-116 annual emissions, reported for 2008-2009 by Mühle et al. (2010). Thus PFC-318 is the third most important PFC in terms of CO2-equivalent emissions. We find mostly baseline conditions at remote AGAGE stations and urban sites in the USA, Europe, and Australia, in contrast to frequent above baseline conditions at Gosan station, Jeju Island, South Korea, indicating significant emission sources in East Asia as found by Saito et al. (2010). Oram, D.E., Trends of long-lived anthropogenic halocarbons in the Southern Hemisphere and model calculation of global emissions, Ph.D. thesis, University

9 CFR 319.301 - Chili con carne with beans.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Chili con carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili con carne with beans. Chili con carne with beans shall contain...

46 CFR 127.320 - Storm rails.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Storm rails. 127.320 Section 127.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS CONSTRUCTION AND ARRANGEMENTS Rails and Guards § 127.320 Storm rails. Suitable storm rails must be installed in each passageway and at...

32 CFR 644.320 - Floodplain management.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Floodplain management. 644.320 Section 644.320... ESTATE HANDBOOK Disposal § 644.320 Floodplain management. The requirements of Executive Order 11988, Floodplain Management, 42 FR 26951, (24 May 1977) and its implementation will be outlined in subpart H (to be...

31 CFR 535.320 - Domestic bank.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Domestic bank. 535.320 Section 535... § 535.320 Domestic bank. (a) The term domestic bank shall mean any branch or office within the United States of any of the following which is not Iran or an Iranian entity: any bank or trust company...

31 CFR 500.320 - Domestic bank.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Domestic bank. 500.320 Section 500... § 500.320 Domestic bank. The term domestic bank shall mean any branch or office within the United States of any of the following which is not a national of any designated foreign country: Any bank or trust...

9 CFR 318.20 - Use of animal drugs.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Use of animal drugs. 318.20 Section... General § 318.20 Use of animal drugs. Animal drug residues are permitted in meat and meat food products if such residues are from drugs which have been approved by the Food and Drug Administration and any such...

TMS320C31 master

International Nuclear Information System (INIS)

Yun, Deok Yong

1999-06-01

The contents of this book are explanation of basic conception for DSP, perfect a complete master of TMS320C31, I/O interface design and memory, practice with PC print port, basic programing skill, assembly and C programing technique, timer and interrupt application skill, serial communication programing technique, application of digital conditioning and application of digital servo control. This book is divided into two parts, which is about TMS320C31 master of theory and application.

7 CFR 1980.320 - Interest rate.

Science.gov (United States)

2010-01-01

... 7 Agriculture 14 2010-01-01 2009-01-01 true Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not... interest rate over the life of the loan. The rate shall be agreed upon by the borrower and the Lender and...

7 CFR 319.77-2 - Regulated articles.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Regulated articles. 319.77-2 Section 319.77-2....77-2 Regulated articles. In order to prevent the spread of gypsy moth from Canada into noninfested... section are designated as regulated articles. Regulated articles may be imported into the United States...

7 CFR 319.40-5 - Importation and entry requirements for specified articles.

Science.gov (United States)

2010-01-01

... requirements in § 319.40-2(a) and the inspection and other requirements in § 319.40-9. Articles being moved..., such as traffic lights or stop signs). If these articles are being moved through the regulated area... accordance with § 319.40-8. (B) The logs must be moved from the port of first arrival to the facility that...

Polarization-insensitive all-optical wavelength conversion of 320 Gb/s RZ-DQPSK signals using a Ti:PPLN waveguide

DEFF Research Database (Denmark)

Hu, Hao; Nouroozi, R.; Ludwig, R.

2010-01-01

Polarization-insensitive wavelength conversion of a single channel 320 Gb/s RZ-DQPSK data signal using a Ti:PPLN waveguide in a bi-directional loop configuration with less than 0.5 dB polarization sensitivity is reported. The conversion efficiency with polarization scrambling of the signal was -2...... little broadening and chirping, indicating the potential for wavelength conversion of even much higher data rates.......Polarization-insensitive wavelength conversion of a single channel 320 Gb/s RZ-DQPSK data signal using a Ti:PPLN waveguide in a bi-directional loop configuration with less than 0.5 dB polarization sensitivity is reported. The conversion efficiency with polarization scrambling of the signal was -21...

33 CFR 96.320 - What is involved to complete a safety management audit and when is it required to be completed?

Science.gov (United States)

2010-07-01

... Safety Management (ISM) Code by Administrations. (3) Make sure the audit is carried out by a team of... safety management audit and when is it required to be completed? 96.320 Section 96.320 Navigation and... SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS How Will Safety Management Systems Be...

9 CFR 319.145 - Italian sausage products.

Science.gov (United States)

2010-01-01

... Section 319.145 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... accordance with § 319.6. When pork muscle tissue is combined with beef or veal, or both, in the preparation... unsmoked product. The product before cooking or smoking shall contain no more than 3 percent water as...

7 CFR 319.56-22 - Apples and pears from certain countries in Europe.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Apples and pears from certain countries in Europe. 319.56-22 Section 319.56-22 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL... Vegetables § 319.56-22 Apples and pears from certain countries in Europe. (a) Importations allowed. The...

7 CFR 319.55-5 - Notice of arrival by permittee.

Science.gov (United States)

2010-01-01

... arrival, the permittee or his agent shall submit a notice, in duplicate, to the Plant Protection and... 7 Agriculture 5 2010-01-01 2010-01-01 false Notice of arrival by permittee. 319.55-5 Section 319.55-5 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH...

7 CFR 319.40-11 - Plant pest risk assessment standards.

Science.gov (United States)

2010-01-01

... analysis to determine the plant pest risks associated with each requested importation in order to determine... 7 Agriculture 5 2010-01-01 2010-01-01 false Plant pest risk assessment standards. 319.40-11... Unmanufactured Wood Articles § 319.40-11 Plant pest risk assessment standards. When evaluating a request to...

320-to-40-Gb/s optical demultiplexing using four-wave mixing in a quantum-dot soa

NARCIS (Netherlands)

Matsuura, M.; Gomez-Agis, F.; Calabretta, N.; Raz, O.; Dorren, H.J.S.

2012-01-01

We report, for the first time, the optical demultiplexing of a 320-Gb/s intensity-modulated signal using four-wave mixing in a quantum-dot semiconductor optical amplifier. Error-free operations were successfully achieved for all the 40-Gb/s channels extracted by the optical demultiplexer.

Discovery and introduction of a (3,18)-connected net as an ideal blueprint for the design of metal-organic frameworks

KAUST Repository

Guillerm, Vincent

2014-06-29

Metal-organic frameworks (MOFs) are a promising class of porous materials because it is possible to mutually control their porous structure, composition and functionality. However, it is still a challenge to predict the network topology of such framework materials prior to their synthesis. Here we use a new rare earth (RE) nonanuclear carboxylate-based cluster as an 18-connected molecular building block to form a gea-MOF (gea-MOF-1) based on a (3,18)-connected net. We then utilized this gea net as a blueprint to design and assemble another MOF (gea-MOF-2). In gea-MOF-2, the 18-connected RE clusters are replaced by metal-organic polyhedra, peripherally functionalized so as to have the same connectivity as the RE clusters. These metal-organic polyhedra act as supermolecular building blocks when they form gea-MOF-2. The discovery of a (3,18)-connected MOF followed by deliberate transposition of its topology to a predesigned second MOF with a different chemical system validates the prospective rational design of MOFs. © 2014 Macmillan Publishers Limited. All rights reserved.

9 CFR 93.319 - Import permit and declaration for horses.

Science.gov (United States)

2010-01-01

... horses. 93.319 Section 93.319 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses Central America and the West Indies 17 § 93.319 Import permit and declaration for horses. For all horses offered for importation from regions of...

7 CFR 319.56-30 - Hass avocados from Michoacan, Mexico.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Hass avocados from Michoacan, Mexico. 319.56-30... § 319.56-30 Hass avocados from Michoacan, Mexico. Fresh Hass variety avocados (Persea americana) may be imported from Michoacan, Mexico, into the United States in accordance with the requirements of § 319.56-3...

42 CFR 412.320 - Disproportionate share adjustment factor.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Disproportionate share adjustment factor. 412.320... Capital-Related Costs § 412.320 Disproportionate share adjustment factor. (a) Criteria for classification... adjustment factor. (1) If a hospital meets the criteria in paragraph (a)(1) of this section for a...

7 CFR 319.8-22 - Ports of entry or export.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Ports of entry or export. 319.8-22 Section 319.8-22... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Foreign Cotton and Covers Miscellaneous Provisions § 319.8-22 Ports of entry or export. When ports of entry or export are not specifically designated...

7 CFR 319.56-24 - Lettuce and peppers from Israel.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Lettuce and peppers from Israel. 319.56-24 Section 319... Lettuce and peppers from Israel. (a) Lettuce may be imported into the United States from Israel without... protected with sticky traps and prophylactic sprays approved for the crop by Israel; (v) The lettuce must be...

47 CFR 68.320 - Supplier's Declaration of Conformity.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Supplier's Declaration of Conformity. 68.320... Approval § 68.320 Supplier's Declaration of Conformity. (a) Supplier's Declaration of Conformity is a... Supplier's Declaration of Conformity attaches to all items subsequently marketed by the responsible party...

Upregulation of microRNA-320 decreases the risk of developing steroid-induced avascular necrosis of femoral head by inhibiting CYP1A2 both in vivo and in vitro.

Science.gov (United States)

Wei, Ji-Hua; Luo, Qun-Qiang; Tang, Yu-Jin; Chen, Ji-Xia; Huang, Chun-Lan; Lu, Ding-Gui; Tang, Qian-Li

2018-06-20

Steroid-induced avascular necrosis of femoral head (SANFH) occurs frequently in patients receiving high-dose steroid treatment for these underlying diseases. The target of this study is to investigate the effect of microRNA-320 (miR-320) on SANFH by targeting CYP1A2. CYP1A2 expression was detected using immunohistochemistry. Specimens were collected from patients with SANFH and femoral neck fracture. Seventy rats were assigned into seven groups. The targeting relationship between miR-320 and CYP1A2 was verified by bioinformatics website and dual luciferase reporter gene assay. RT-qPCR and Western blot analysis were used to detect miR-320 and CYP1A2 expressions. The enzymatic activity of CYP1A2 was detected by fluorescence spectrophotometry. Hemorheology and microcirculation were measured in rats. MiR-320 expression decreased and CYP1A2 expression and enzymatic activity increased in SANFH patients compared to those with femoral neck fracture. CYP1A2 was the target gene of miR-320. Hemorheology and microcirculation results showed that up-regulated expression of CYP1A2 promoted the development of SANFH while increased expression of miR-320 inhibited the development of SANFH. Compared with the SANFH group, the SANFH + miR-320 mimic group showed increased miRNA-320 expression, and decreased CYP1A2 expression and enzymatic activity. Opposite results were found in the SANFH + miR-320 inhibitor group. The SANFH + miR-320 inhibitor + pCR-CYP1A2_KO group showed decreased miRNA-320 expression and the SANFH + pCR-CYP1A2_KO group showed decreased CYP1A2 expression and enzymatic activity. Our findings provide evidences that miR-320 might inhibit the development of SANFH by targeting CYP1A2. Copyright © 2018 Elsevier B.V. All rights reserved.

7 CFR 319.59-1 - Definitions.

Science.gov (United States)

2010-01-01

..., DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Wheat Diseases § 319.59-1 Definitions. Administrator... disease caused by the fungus Tilletia indica (Mitra) Mundkur. Plant. Any plant (including any plant part) for or capable of propagation, including a tree, a tissue culture, a plantlet culture, pollen, a shrub...

7 CFR 319.75-7 - Costs and charges.

Science.gov (United States)

2010-01-01

..., and shall be performed under the supervision of an inspector. Plant Protection and Quarantine will not... 7 Agriculture 5 2010-01-01 2010-01-01 false Costs and charges. 319.75-7 Section 319.75-7 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

9 CFR 319.307 - Spaghetti sauce with meat.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Spaghetti sauce with meat. 319.307... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... Dehydrated Meat Food Products § 319.307 Spaghetti sauce with meat. “Spaghetti Sauce with Meat” shall contain...

31 CFR 597.319 - U.S. financial institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. financial institution. 597.319 Section 597.319 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... financial institution's foreign branches; (b) Any financial institution operating or doing business in the...

31 CFR 560.319 - United States depository institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States depository institution. 560.319 Section 560.319 Money and Finance: Treasury Regulations Relating to Money and Finance... entity, that is engaged primarily in the business of banking (for example, banks, savings banks, savings...

31 CFR 537.319 - U.S. depository institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. depository institution. 537.319 Section 537.319 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE..., that is engaged primarily in the business of banking (for example, banks, savings banks, savings...

9 CFR 318.23 - Heat-processing and stabilization requirements for uncured meat patties.

Science.gov (United States)

2010-01-01

... requirements for uncured meat patties. 318.23 Section 318.23 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY... uncured meat patties. (a) Definitions. For purposes of this section, the following definitions shall apply...

7 CFR 319.8-26 - Material refused entry.

Science.gov (United States)

2010-01-01

... Plant Protection Act (7 U.S.C. 7714 and 7731). Neither the Department of Agriculture nor the inspector... 7 Agriculture 5 2010-01-01 2010-01-01 false Material refused entry. 319.8-26 Section 319.8-26 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

7 CFR 319.55-2 - Application for permit.

Science.gov (United States)

2010-01-01

... rice hulls from any country, may be made to the Plant Protection and Quarantine Programs, indicating in... 7 Agriculture 5 2010-01-01 2010-01-01 false Application for permit. 319.55-2 Section 319.55-2 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

7 CFR 319.56-49 - Eggplant from Israel.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Eggplant from Israel. 319.56-49 Section 319.56-49... from Israel. Eggplant (Solanum melongena L.) may be imported into the continental United States from Israel only under the conditions described in this section. These conditions are designed to prevent the...

31 CFR 540.319 - U.S. financial institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. financial institution. 540.319... CONTROL REGULATIONS General Definitions § 540.319 U.S. financial institution. The term U.S. financial... financial institutions that are located in the United States, but not such institutions' foreign branches...

49 CFR 178.318 - Specification MC 201; container for detonators and percussion caps.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Specification MC 201; container for detonators and percussion caps. 178.318 Section 178.318 Transportation Other Regulations Relating to Transportation PIPELINE....318 Specification MC 201; container for detonators and percussion caps. ...

7 CFR 319.56-34 - Clementines from Spain.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Clementines from Spain. 319.56-34 Section 319.56-34... Clementines from Spain. Clementines (Citrus reticulata) from Spain may only be imported into the United States... agreement. Clementines from Spain may be imported only if the Government of Spain or its designated...

31 CFR 598.319 - U.S. financial institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. financial institution. 598.319... General Definitions § 598.319 U.S. financial institution. The term U.S. financial institution means any U..., offices, and agencies of foreign financial institutions which are located in the United States, but not...

W-320 Department of Health documentation

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

The purpose of this document is to gather information required to show that Project W-320 is in compliance with Washington State Department of Health requirements as specified in Radioactive Air Emissions Notice of Construction Project W-320, Tank 241-C-106 Sluicing, DOE/RL-95-45. Specifically, that W-320 is in compliance with ASME N509-1989 (Nuclear Power Plant Air-Cleaning Units and Components) and ASME N5 10-1989 (Testing of Nuclear Air Treatment Systems) for the 296-C-006 exhaust system

W-320 Department of Health documentation

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-08-07

The purpose of this document is to gather information required to show that Project W-320 is in compliance with Washington State Department of Health requirements as specified in Radioactive Air Emissions Notice of Construction Project W-320, Tank 241-C-106 Sluicing, DOE/RL-95-45. Specifically, that W-320 is in compliance with ASME N509-1989 (Nuclear Power Plant Air-Cleaning Units and Components) and ASME N5 10-1989 (Testing of Nuclear Air Treatment Systems) for the 296-C-006 exhaust system.

The 5 Hour Pulse Period and Broadband Spectrum of the Symbiotic X-Ray Binary 3A 1954+319

Science.gov (United States)

Marcu, Diana M.; Fuerst, Felix; Pottschmidt, Katja; Grinberg, Victoria; Miller, Sebstian; Wilms, Joern; Postnov, Konstantin A.; Corbet, Robin H. D.; Markwardt, Craig B.; Cadolle Bel, Marion

2011-01-01

We present an analysis of the highly variable accreting X-ray pulsar 3A 1954+319 using 2005-2009 monitoring data obtained with INTEGRAL and Swift. This considerably extends the pulse period history and covers flaring episodes in 2005 and 2008. In 2006 the source was identified as one of only a few known symbiotic X-ray binaries, Le" systems composed of a neutron star accreting from the inhomogeneous medium around an M-giant star. The extremely long pulse period of approximately 5.3 h is directly visible in the 2008 INTEGRAL-ISGRI outburst light curve. The pulse profile is double peaked and not significantly energy dependent. During the outburst a strong spin-up of -1.8 x 10(exp -4) h h(exp -1) occurred. Between 2005 and 2008 a long term spin-down trend of 2.1 x 10(exp -5) h h(exp -1) was observed for the first time for this source. The 3-80 keV pulse peak spectrum of 3A 1954+319 during the 2008 flare could be well described by a thermal Comptonization model. We interpret the results within the framework of a recently developed quasi-spherical accretion model for symbiotic X-ray binaries.

32 CFR 320.2 - Definitions.

Science.gov (United States)

2010-07-01

... NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.2 Definitions. As used in this part: (a... as a finger or voice print or a photograph. (g) Routine use. The disclosure of a record outside the...

Polymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder.

Science.gov (United States)

Archer, Simon N; Carpen, Jayshan D; Gibson, Mark; Lim, Gim Hui; Johnston, Jonathan D; Skene, Debra J; von Schantz, Malcolm

2010-05-01

To screen the PER3 promoter for polymorphisms and investigate the phenotypic associations of these polymorphisms with diurnal preference, delayed sleep phase disorder/syndrome (DSPD/DSPS), and their effects on reporter gene expression. Interspecific comparison was used to define the approximate extent of the PER3 promoter as the region between the transcriptional start site and nucleotide position -874. This region was screened in DNA pools using PCR and direct sequencing, which was also used to screen DNA from individual participants. The different promoter alleles were cloned into a luciferase expression vector and a deletion library created. Promoter activation was measured by chemiluminescence. N/A. DNA samples were obtained from volunteers with defined diurnal preference (3 x 80, selected from a pool of 1,590), and DSPD patients (n=23). N/A. We verified three single nucleotide polymorphisms (G -320T, C -319A, G -294A), and found a novel variable number tandem repeat (VNTR) polymorphism (-318 1/2 VNTR). The -320T and -319A alleles occurred more frequently in DSPD compared to morning (P = 0.042 for each) or evening types (P = 0.006 and 0.033). The allele combination TA2G was more prevalent in DSPD compared to morning (P 0.033) or evening types (P = 0.002). Luciferase expression driven by the TA2G combination was greater than for the more common GC2A (P < 0.05) and the rarer TA1G (P < 0.001) combinations. Deletion reporter constructs identified two enhancer regions (-703 to -605, and -283 to -80). Polymorphisms in the PER3 promoter could affect its expression, leading to potential differences in the observed functions of PER3.

9 CFR 318.303 - Critical factors and the application of the process schedule.

Science.gov (United States)

2010-01-01

... of the process schedule. 318.303 Section 318.303 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY...; REINSPECTION AND PREPARATION OF PRODUCTS Canning and Canned Products § 318.303 Critical factors and the...

32 CFR 318.15 - Rules of conduct

Science.gov (United States)

2010-07-01

... DEFENSE THREAT REDUCTION AGENCY PRIVACY PROGRAM § 318.15 Rules of conduct (a) DTRA personnel shall: (1... of records, to which they have access or are using incident to the conduct of official business, shall be protected so that the security and confidentiality of the information shall be preserved. (2...

9 CFR 319.313 - Beef with gravy and gravy with beef.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Beef with gravy and gravy with beef. 319.313 Section 319.313 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... Dehydrated Meat Food Products § 319.313 Beef with gravy and gravy with beef. “Beef with Gravy” and “Gravy...

7 CFR 319.8-12 - From the West Coast of Mexico.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false From the West Coast of Mexico. 319.8-12 Section 319.8... Conditions for the Entry of Cotton and Covers from Mexico § 319.8-12 From the West Coast of Mexico. Contingent upon continued freedom of the West Coast of Mexico and of Northwest Mexico from infestations of...

78 FR 41280 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2013-07-10

... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A319-112, -113, and -132 airplanes; Model A320-211, -212, -214, -231, and -232 airplanes... A319 aeroplane on which Airbus modification (mod.) 22058 had been embodied in production. Airbus mod...

36 CFR 3.18 - May I snorkel or underwater dive in park waters?

Science.gov (United States)

2010-07-01

... dive in park waters? 3.18 Section 3.18 Parks, Forests, and Public Property NATIONAL PARK SERVICE... waters? (a) Snorkeling and underwater diving is allowed in park waters, subject to closures or restrictions designated by the superintendent in accordance with §§ 1.5 and 1.7 of this chapter. (b) In waters...

TMS320C31

International Nuclear Information System (INIS)

Park, Gwi Tae; Lee, Sang Rak

1998-01-01

This book is divided into four parts, which introduces TMS320C31 with C language. The first part deals with digital signal processor on what is DPS?, types of DPS and structure of TMS320C31. The second part introduces program development by C language, cstartup cord and C compiler. The third part describes OS30, Emile 30 and BIOS. The last part is for application board design of T31 and test examples of T31 board : external flag test, ram test, external read port test and communication test.

7 CFR 319.8-8 - Lint, linters, and waste.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Lint, linters, and waste. 319.8-8 Section 319.8-8 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION... Britain and Northern Ireland (United Kingdom), Iceland, Liechtenstein, Luxembourg, Netherlands, Norway...

Signal-on electrochemiluminescence biosensor for microRNA-319a detection based on two-stage isothermal strand-displacement polymerase reaction.

Science.gov (United States)

Wang, Minghui; Zhou, Yunlei; Yin, Huanshun; Jiang, Wenjing; Wang, Haiyan; Ai, Shiyun

2018-06-01

MicroRNAs play crucial role in regulating gene expression in organism, thus it is very necessary to exploit an efficient method for the sensitive and specific detection of microRNA. Herein, a signal-on electrochemiluminescence biosensor was fabricated for microRNA-319a detection based on two-stage isothermal strand-displacement polymerase reaction (ISDPR). In the presence of target microRNA, amounts of trigger DNA could be generated by the first ISDPR. Then, the trigger DNA and the primer hybridized simultaneously with the hairpin probe to open the stem of the probe, and then the ECL signal will be emitted. In the presence of phi29 DNA polymerase and dNTPs, the trigger DNA could be displaced to initiate a new cycle which was the second ISDPR. Due to the two-stage amplification, this method presented excellent detection sensitivity with a low detection limit of 0.14 fM. Moreover, the applicability of the developed method was demonstrated by detecting the change of microRNA-319a content in the leaves of rice seedlings after the rice seeds were incubated with chemical mutagen of ethyl methanesulfonate. Copyright © 2018 Elsevier B.V. All rights reserved.

13 CFR 108.320 - Contents of comprehensive business plan.

Science.gov (United States)

2010-01-01

... plan. 108.320 Section 108.320 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS... Contents of comprehensive business plan. (a) Executive summary. The executive summary must include a... or entity, or any other firm or entity essential to the success of the Applicant's business plan. [66...

7 CFR 3052.320 - Report submission.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Report submission. 3052.320 Section 3052.320 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 3052...

21 CFR 176.320 - Sodium nitrate-urea complex.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Sodium nitrate-urea complex. 176.320 Section 176... Substances for Use Only as Components of Paper and Paperboard § 176.320 Sodium nitrate-urea complex. Sodium nitrate-urea complex may be safely used as a component of articles intended for use in producing...

24 CFR 235.320 - Limitation of sales price.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Limitation of sales price. 235.320 Section 235.320 Housing and Urban Development Regulations Relating to Housing and Urban Development... Payments-Homes for Lower Income Families § 235.320 Limitation of sales price. To qualify for assistance...

24 CFR 91.320 - Action plan.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Action plan. 91.320 Section 91.320 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development...), evaluate and reduce lead-based paint hazards, reduce the number of poverty level families, develop...

24 CFR 320.10 - Financial reporting.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Financial reporting. 320.10 Section...-BACKED SECURITIES Pass-Through Type Securities § 320.10 Financial reporting. Issuers shall submit to the Association audited annual financial statements within 90 days of their fiscal year end. All financial...

7 CFR 319.56-10 - Importation of fruits and vegetables from Canada.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Importation of fruits and vegetables from Canada. 319... Vegetables § 319.56-10 Importation of fruits and vegetables from Canada. (a) General permit for fruits and vegetables grown in Canada. Fruits and vegetables grown in Canada and offered for entry into the United...

39 CFR 320.7 - Suspension for advertisements accompanying parcels or periodicals.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Suspension for advertisements accompanying parcels or periodicals. 320.7 Section 320.7 Postal Service UNITED STATES POSTAL SERVICE RESTRICTIONS ON PRIVATE CARRIAGE OF LETTERS SUSPENSION OF THE PRIVATE EXPRESS STATUTES § 320.7 Suspension for advertisements accompanying parcels or periodicals. (a) Th...

7 CFR 318.47-4 - Shipments by the Department of Agriculture.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Shipments by the Department of Agriculture. 318.47-4 Section 318.47-4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE STATE OF HAWAII AND TERRITORIES QUARANTINE NOTICES...

9 CFR 319.29 - Miscellaneous pork products.

Science.gov (United States)

2010-01-01

... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Raw Meat Products § 319.29... fatty tissue, exclusive of skin. Such product shall have a pinkish color and a fresh odor and appearance. ...

42 CFR 403.320 - CMS review and monitoring of State systems.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false CMS review and monitoring of State systems. 403.320 Section 403.320 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Systems § 403.320 CMS review and monitoring of State systems. (a) General rule. The State must submit an...

320 Gb/s Nyquist OTDM received by polarization-insensitive time-domain OFT

DEFF Research Database (Denmark)

Hu, Hao; Kong, Deming; Palushani, Evarist

2014-01-01

We have demonstrated the generation of a 320 Gb/s Nyquist-OTDM signal by rectangular filtering on an RZ-OTDM signal with the filter bandwidth (320 GHz) equal to the baud rate (320 Gbaud) and the reception of such a Nyquist-OTDM signal using polarization-insensitive time-domain optical Fourier tra...

42 CFR 433.320 - Procedures for refunds to CMS.

Science.gov (United States)

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Procedures for refunds to CMS. 433.320 Section 433... Overpayments to Providers § 433.320 Procedures for refunds to CMS. (a) Basic requirements. (1) The agency must refund the Federal share of overpayments that are subject to recovery to CMS through a credit on its...

49 CFR 350.319 - What are permissible uses of High Priority Activity Funds?

Science.gov (United States)

2010-10-01

... Activity Funds? 350.319 Section 350.319 Transportation Other Regulations Relating to Transportation... permissible uses of High Priority Activity Funds? (a) The FMCSA may generally use these funds to support, enrich, or evaluate State CMV safety programs and to accomplish the five objectives listed below: (1...

7 CFR 1207.320 - Establishment and membership.

Science.gov (United States)

2010-01-01

....320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan National Potato Promotion Board § 1207.320...

Inductive sensor for lightning current measurement, fitted in aircraft windows, part II: Measurements on an A320 aircraft

NARCIS (Netherlands)

Deursen, van A.P.J.

2011-01-01

A novel sensor for the detection of the lightning current through the fuselage of an aircraft has been tested on an A320 aircraft. An accurate method-of-moment model of the window edge provided reliable calibration of the sensor for external fields. The data have been analyzed and the good

36 CFR 13.320 - Preference to Cook Inlet Region, Incorporated.

Science.gov (United States)

2010-07-01

... Region, Incorporated. 13.320 Section 13.320 Parks, Forests, and Public Property NATIONAL PARK SERVICE... to Cook Inlet Region, Incorporated. (a) The Cook Inlet Region, Incorporated (CIRI), in cooperation with village corporations within the Cook Inlet region when appropriate, will have a right of first...

28 CFR 32.0 - Scope of part.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Scope of part. 32.0 Section 32.0 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE...) Educational assistance benefits. [73 FR 76528, Dec. 17, 2008] ...

Microstructural evolution and thixoformability of semi-solid aluminum 319s alloy during re-melting

International Nuclear Information System (INIS)

Hu, X.G.; Zhu, Q.; Lu, H.X.; Zhang, F.; Li, D.Q.; Midson, S.P.

2015-01-01

The aim of this paper is to characterize both microstructural evolution and thixoformability during partial melting of semi-solid 319s alloy. The thixoformability criteria of 319s was initially investigated by thermodynamic analysis. In-situ observation of partial re-melting was performed by a Confocal Laser Scanning Microscope to determine the effect of heating rate on melting characteristics. Meanwhile, the microstructural evolution of 319s alloy at extremely low heating rate was also investigated in order to understand the mechanism of re-melting process. The studies demonstrated that 319s alloy is suitable for thixocasting because of the controllable liquid fraction in the operating window of 15 °C. The process window was effected by both temperature and heating time. The primary particles evolution in 319s alloy can be divided into four stages, and the coarsening rate during isothermal test is 227 μm 3 /s. The effective method to obtain desirable microstructure is to manage the time in the semi-solid state by controlling heating rate and soaking time. - Highlights: • The thixoformability of 319s is discussed by using SPSC and thermodynamic analysis. • The re-melting processes at different heating rate are in-situ observed. • We identified the four stages of microstructural evolution during re-melting. • The coarsening rate K for 319s during isothermal test is identified. • The variation tendency of Si particle size with increasing time is reported

Software pi/4 DQPSK Modem: A Student Project Using the TMS320-C6201 EVM Board

OpenAIRE

Weiss, S; Braithwaite, SJ; Stewart, RD

2000-01-01

This paper reports on a student project performed at the University of Southampton jointly by 4th year MEng students within the course "Advanced Radio Communications". The aim was to design a software modem capable of transmitting 16kb/s of data, whereby random number generation, advanced modulation, pulse shaping, synchronisation, and error counting techniques had to be applied. The ultimate aim was the implementation on a Texas Instruments TMS320-C6201 EVM board, which dictated some of the ...

Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography and (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: results of a prospective clinical trial.

Science.gov (United States)

Schuster, David M; Nieh, Peter T; Jani, Ashesh B; Amzat, Rianot; Bowman, F Dubois; Halkar, Raghuveer K; Master, Viraj A; Nye, Jonathon A; Odewole, Oluwaseun A; Osunkoya, Adeboye O; Savir-Baruch, Bital; Alaei-Taleghani, Pooneh; Goodman, Mark M

2014-05-01

We prospectively evaluated the amino acid analogue positron emission tomography radiotracer anti-3-[(18)F]FACBC compared to ProstaScint® ((111)In-capromab pendetide) single photon emission computerized tomography-computerized tomography to detect recurrent prostate carcinoma. A total of 93 patients met study inclusion criteria who underwent anti-3-[(18)F]FACBC positron emission tomography-computerized tomography plus (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for suspected recurrent prostate carcinoma within 90 days. Reference standards were applied by a multidisciplinary board. We calculated diagnostic performance for detecting disease. In the 91 of 93 patients with sufficient data for a consensus on the presence or absence of prostate/bed disease anti-3-[(18)F]FACBC had 90.2% sensitivity, 40.0% specificity, 73.6% accuracy, 75.3% positive predictive value and 66.7% negative predictive value compared to (111)In-capromab pendetide with 67.2%, 56.7%, 63.7%, 75.9% and 45.9%, respectively. In the 70 of 93 patients with a consensus on the presence or absence of extraprostatic disease anti-3-[(18)F]FACBC had 55.0% sensitivity, 96.7% specificity, 72.9% accuracy, 95.7% positive predictive value and 61.7% negative predictive value compared to (111)In-capromab pendetide with 10.0%, 86.7%, 42.9%, 50.0% and 41.9%, respectively. Of 77 index lesions used to prove positivity histological proof was obtained in 74 (96.1%). Anti-3-[(18)F]FACBC identified 14 more positive prostate bed recurrences (55 vs 41) and 18 more patients with extraprostatic involvement (22 vs 4). Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography correctly up-staged 18 of 70 cases (25.7%) in which there was a consensus on the presence or absence of extraprostatic involvement. Better diagnostic performance was noted for anti-3-[(18)F]FACBC positron emission tomography-computerized tomography than for (111)In-capromab pendetide single

27 CFR 24.319 - Carbon dioxide record.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Carbon dioxide record. 24..., DEPARTMENT OF THE TREASURY LIQUORS WINE Records and Reports § 24.319 Carbon dioxide record. A proprietor who uses carbon dioxide in still wine shall maintain a record of the laboratory tests conducted to...

7 CFR 319.37-3 - Permits.

Science.gov (United States)

2010-01-01

...; (2) Articles subject to the postentry quarantine conditions of § 319.37-7; (3) Bulbs of Allium sativum (garlic), Crocosmia spp. (montebretia), Gladiolus spp. (gladiolus), and Watsonia spp. (bugle lily...

7 CFR 319.56-45 - Shelled garden peas from Kenya.

Science.gov (United States)

2010-01-01

... phytosanitary certificate of inspection issued by the national plant protection organization of Kenya bearing... 7 Agriculture 5 2010-01-01 2010-01-01 false Shelled garden peas from Kenya. 319.56-45 Section 319.56-45 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH...

9 CFR 318.10 - Prescribed treatment of pork and products containing pork to destroy trichinae.

Science.gov (United States)

2010-01-01

... products containing pork to destroy trichinae. 318.10 Section 318.10 Animals and Animal Products FOOD... ESTABLISHMENTS; REINSPECTION AND PREPARATION OF PRODUCTS General § 318.10 Prescribed treatment of pork and... thorough cooking because of the appearance of the finished product or otherwise. Cured boneless pork loins...

9 CFR 319.312 - Pork with barbecue sauce and beef with barbecue sauce.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Pork with barbecue sauce and beef with barbecue sauce. 319.312 Section 319.312 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE..., Frozen, or Dehydrated Meat Food Products § 319.312 Pork with barbecue sauce and beef with barbecue sauce...

9 CFR 318.15 - Tagging chemicals, preservatives, cereals, spices, etc., “U.S. retained.”

Science.gov (United States)

2010-01-01

..., cereals, spices, etc., âU.S. retained.â 318.15 Section 318.15 Animals and Animal Products FOOD SAFETY AND...; REINSPECTION AND PREPARATION OF PRODUCTS General § 318.15 Tagging chemicals, preservatives, cereals, spices, etc., “U.S. retained.” When any chemical, preservative, cereal, spice, or other substance is intended...

7 CFR 319.41-4 - Notice of arrival by permittee.

Science.gov (United States)

2010-01-01

... Plant Protection and Quarantine Programs, through the U.S. Collector of Customs, or, in the case of Guam... 7 Agriculture 5 2010-01-01 2010-01-01 false Notice of arrival by permittee. 319.41-4 Section 319.41-4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH...

21 CFR 333.320 - Permitted combinations of active ingredients.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Permitted combinations of active ingredients. 333.320 Section 333.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Note: At 75 FR 9776, Mar. 4, 2010, § 333.320 was revised, effective Mar. 4, 2011. For the convenience...

26 CFR 1.318-1 - Constructive ownership of stock; introduction.

Science.gov (United States)

2010-04-01

... individual under a decree of divorce or separate maintenance), and by or for his children, grandchildren, and... corporation shall not be considered to own its own stock by reason of section 318(a)(3)(C); (2) In any case in...

48 CFR 319.501 - General.

Science.gov (United States)

2010-10-01

... BUSINESS PROGRAMS Set-Asides for Small Business 319.501 General. (e) Subsequent to the Contracting Officer's recommendation on Form HHS 653, HHS Small Business Review Form, the SBS shall review each proposed acquisition strategy and either concur or not concur with the Contracting Officer's recommendation. The PCR...

9 CFR 319.107 - Bacon.

Science.gov (United States)

2010-01-01

... AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Cured Meats, Unsmoked and Smoked § 319.107 Bacon. The weight of cured pork bellies ready for slicing and labeling as “Bacon” shall not exceed the...

3D CT cerebral angiography technique using a 320-detector machine with a time–density curve and low contrast medium volume: Comparison with fixed time delay technique

International Nuclear Information System (INIS)

Das, K.; Biswas, S.; Roughley, S.; Bhojak, M.; Niven, S.

2014-01-01

Aim: To describe a cerebral computed tomography angiography (CTA) technique using a 320-detector CT machine and a small contrast medium volume (35 ml, 15 ml for test bolus). Also, to compare the quality of these images with that of the images acquired using a larger contrast medium volume (90 or 120 ml) and a fixed time delay (FTD) of 18 s using a 16-detector CT machine. Materials and methods: Cerebral CTA images were acquired using a 320-detector machine by synchronizing the scanning time with the time of peak enhancement as determined from the time–density curve (TDC) using a test bolus dose. The quality of CTA images acquired using this technique was compared with that obtained using a FTD of 18 s (by 16-detector CT), retrospectively. Average densities in four different intracranial arteries, overall opacification of arteries, and the degree of venous contamination were graded and compared. Results: Thirty-eight patients were scanned using the TDC technique and 40 patients using the FTD technique. The arterial densities achieved by the TDC technique were higher (significant for supraclinoid and basilar arteries, p < 0.05). The proportion of images deemed as having “good” arterial opacification was 95% for TDC and 90% for FTD. The degree of venous contamination was significantly higher in images produced by the FTD technique (p < 0.001%). Conclusion: Good diagnostic quality CTA images with significant reduction of venous contamination can be achieved with a low contrast medium dose using a 320-detector machine by coupling the time of data acquisition with the time of peak enhancement

THE EXTREMELY RED, YOUNG L DWARF PSO J318.5338–22.8603: A FREE-FLOATING PLANETARY-MASS ANALOG TO DIRECTLY IMAGED YOUNG GAS-GIANT PLANETS

Energy Technology Data Exchange (ETDEWEB)

Liu, Michael C.; Magnier, Eugene A.; Kotson, Michael C.; Aller, Kimberly M.; Burgett, W. S.; Chambers, K. C.; Hodapp, K. W.; Jedicke, R.; Kaiser, N.; Kudritzki, R.-P.; Morgan, J. S.; Tonry, J. L.; Wainscoat, R. J. [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Deacon, Niall R. [Max Planck Institute for Astronomy, Konigstuhl 17, D-69117 Heidelberg (Germany); Allers, Katelyn N. [Department of Physics and Astronomy, Bucknell University, Lewisburg, PA 17837 (United States); Dupuy, Trent J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Draper, P. W.; Price, P. A. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Metcalfe, N. [Department of Physics, Durham University, South Road, Durham DH1 3LE (United Kingdom)

2013-11-10

We have discovered using Pan-STARRS1 an extremely red late-L dwarf, which has (J – K){sub MKO} = 2.78 and (J – K){sub 2MASS} = 2.84, making it the reddest known field dwarf and second only to 2MASS J1207–39b among substellar companions. Near-IR spectroscopy shows a spectral type of L7 ± 1 and reveals a triangular H-band continuum and weak alkali (K I and Na I) lines, hallmarks of low surface gravity. Near-IR astrometry from the Hawaii Infrared Parallax Program gives a distance of 24.6 ± 1.4 pc and indicates a much fainter J-band absolute magnitude than field L dwarfs. The position and kinematics of PSO J318.5–22 point to membership in the β Pic moving group. Evolutionary models give a temperature of 1160{sup +30}{sub -40} K and a mass of 6.5{sup +1.3}{sub -1.0} M {sub Jup}, making PSO J318.5–22 one of the lowest mass free-floating objects in the solar neighborhood. This object adds to the growing list of low-gravity field L dwarfs and is the first to be strongly deficient in methane relative to its estimated temperature. Comparing their spectra suggests that young L dwarfs with similar ages and temperatures can have different spectral signatures of youth. For the two objects with well constrained ages (PSO J318.5–22 and 2MASS J0355+11), we find their temperatures are ≈400 K cooler than field objects of similar spectral type but their luminosities are similar, i.e., these young L dwarfs are very red and unusually cool but not 'underluminous'. Altogether, PSO J318.5–22 is the first free-floating object with the colors, magnitudes, spectrum, luminosity, and mass that overlap the young dusty planets around HR 8799 and 2MASS J1207–39.

Physics properties of non-helical scan using 320-row multi detector computed tomography

International Nuclear Information System (INIS)

Urikura, Atsushi; Nakaya, Yoshihiro; Kawatani, Keisuke; Kawashima, Ippei; Goto, Hironori; Ichikawa, Katsuhiro

2012-01-01

Recently, clinical applications utilizing 320-row multi detector computed tomography (320MDCT) have increased, and the physical image properties of 320MDCT have been more concerned. We evaluated the spatial resolution in scan plane and z-direction, image noise and low-contrast sensitivity of non-helical mode (320NH), 640 slices mode by a double slice reconstruction technology (640DS), and 64-row helical mode (64HE) by using a 320MDCT. The spatial resolution in z-direction was evaluated by the section sensitivity profile (SSP) measurement with the micro coin phantom and the contrast transfer ratio (CTR) with the 0.5-mm comb phantom. The in-plane spatial resolution of 320NH was uniform over all the slice positions. The spatial resolution in z-direction decreased from the cathode side toward the anode side. The image noise of the anode side was higher than that of the cathode side. The contrast to noise ratio as index of the low contrast sensitivity was uniform over all the slice position. The CTR of 320NH fluctuated in the z-position, and the fluctuation was improved by 640DS except for the center of rotation. (author)

7 CFR 319.8-20 - Importations by the Department of Agriculture.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Importations by the Department of Agriculture. 319.8-20 Section 319.8-20 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Foreign Cotton and...

Lithium doping on covalent organic framework-320 for enhancing hydrogen storage at ambient temperature

Energy Technology Data Exchange (ETDEWEB)

Xia, Liangzhi, E-mail: 15004110853@163.com; Liu, Qing

2016-12-15

Density Functional Theory (DFT) combines with grand canonical Monte Carlo (GCMC) simulations are performed to explore the effect of Li doping on the hydrogen storage capability of COF-320. The results show that the interaction energy between the H{sub 2} and the Li-doped COF-320 is about three times higher than that of pristine COF-320. GCMC simulations are employed to study the hydrogen uptake of Li-doped COF-320 at ambient temperature, further confirm that the lithium doping can improve the hydrogen uptake at ambient temperature. Our results demonstrate that Li-doped COFs have good potential in the field of hydrogen storage. - Graphical abstract: Fig. 1. The optimized cluster model used here to represent the COF-320 and possible adsorption sites (A, B, C) for adsorption of metals in the COF-320. The dangling bonds are terminated by H atoms. C, H, and N atoms are shown as gray, white, and blue colors, respectively. Fig. 2. The adsorption isotherm of H{sub 2} in the pristine and Li-doped COF-320 at 298 K. - Highlights: • The binding sites of single and two lithium atoms in COF-320 were studied. • The interaction energy between the H{sub 2} and the Li-doped COF-320 is about three times higher than that of pristine COF-320. • H{sub 2} uptakes on the Li-doped COFs obtain significant improvement at ambient temperature. • Lithium-doping is a successful strategy for improving hydrogen uptake.

Lithium doping on covalent organic framework-320 for enhancing hydrogen storage at ambient temperature

International Nuclear Information System (INIS)

Xia, Liangzhi; Liu, Qing

2016-01-01

Density Functional Theory (DFT) combines with grand canonical Monte Carlo (GCMC) simulations are performed to explore the effect of Li doping on the hydrogen storage capability of COF-320. The results show that the interaction energy between the H 2 and the Li-doped COF-320 is about three times higher than that of pristine COF-320. GCMC simulations are employed to study the hydrogen uptake of Li-doped COF-320 at ambient temperature, further confirm that the lithium doping can improve the hydrogen uptake at ambient temperature. Our results demonstrate that Li-doped COFs have good potential in the field of hydrogen storage. - Graphical abstract: Fig. 1. The optimized cluster model used here to represent the COF-320 and possible adsorption sites (A, B, C) for adsorption of metals in the COF-320. The dangling bonds are terminated by H atoms. C, H, and N atoms are shown as gray, white, and blue colors, respectively. Fig. 2. The adsorption isotherm of H 2 in the pristine and Li-doped COF-320 at 298 K. - Highlights: • The binding sites of single and two lithium atoms in COF-320 were studied. • The interaction energy between the H 2 and the Li-doped COF-320 is about three times higher than that of pristine COF-320. • H 2 uptakes on the Li-doped COFs obtain significant improvement at ambient temperature. • Lithium-doping is a successful strategy for improving hydrogen uptake.

Evaluation of a Non-Nuclear Soil Density Gauge on Fine-Grained Soils

Science.gov (United States)

2013-05-01

U.S. STANDARD SIEVE NUMBERS HYDROMETER fY, in o/. in. 318 in #140 6 in. 3 in. 2 in. 1 in. ’A in #4 ’" #20 #30 #40 ឬ #100 #200 100 J I ’ I I I I I...1 3-20 31 C L-2 U.S. SIEVE OPENING IN INCHES U.S. STANDARD SIEVE NUMBERS HYDROMETER 1Y,in. ’/.in Un~/8 in #140 6 in 3 in. 2 in. 1in. " #4...Particle Size Distribution Reoort Fine PL 14 HYDROMETER %Fines Silt -------,---- PI Project Non-Nuclear Gau_ge Proiect 27 Area Boring No. 3 Date

20 CFR 30.318 - Can the FAB consider objections to HHS's reconstruction of a radiation dose or to the guidelines...

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Can the FAB consider objections to HHS's... OF 2000, AS AMENDED Adjudicatory Process Hearings and Final Decisions on Claims § 30.318 Can the FAB... to HHS's reconstruction of the radiation dose to which the employee was exposed, the FAB will...

7 CFR 319.56-37 - Grapes from the Republic of Korea.

Science.gov (United States)

2010-01-01

... season by the Republic of Korea's national plant protection organization (NPPO). The NPPO will inspect... 7 Agriculture 5 2010-01-01 2010-01-01 false Grapes from the Republic of Korea. 319.56-37 Section 319.56-37 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH...

42 CFR 495.320 - FFP for payments to Medicaid providers.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false FFP for payments to Medicaid providers. 495.320 Section 495.320 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.320 FFP for payments to Medicaid...

21 CFR 320.38 - Retention of bioavailability samples.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Retention of bioavailability samples. 320.38... (CONTINUED) DRUGS FOR HUMAN USE BIOAVAILABILITY AND BIOEQUIVALENCE REQUIREMENTS Procedures for Determining the Bioavailability or Bioequivalence of Drug Products § 320.38 Retention of bioavailability samples...

8 CFR 320.1 - What definitions are used in this part?

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false What definitions are used in this part? 320.1 Section 320.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS CHILD... the existence of a final adoption decree. In the case of a child of divorced or legally separated...

7 CFR 318.13-12 - Movement by the U.S. Department of Agriculture.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Movement by the U.S. Department of Agriculture. 318.13-12 Section 318.13-12 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE STATE OF HAWAII AND TERRITORIES QUARANTINE...

RX J1759.4+6638: An x-ray selected quasars at a redshift of 4.320

Science.gov (United States)

Henry, J. P.; Gioia, I. M.; Boehringer, H.; Bower, R. G.; Briel, U. G.; Hasinger, G. H.; Aragon-Salamanca, A.; Castander, F. J.; Ellis, R. S.; Huchra, J. P.

1994-01-01

We report the discovery of an x-ray selected Quasi-Stellar Objects (QSO) at a redshift of 4.320 +/- 0.005. This is the most distant x-ray selected object known, and it is the eighth most distant QSO known. The properties of this QSO are very similar to other QSOs at redshifts greater than 4. The x-ray discovery of this object, and that of high redshift clusters of galaxies, shows that present x-ray surveys are reaching depths competitive with other methods.

7 CFR 51.319 - Seriously deformed.

Science.gov (United States)

2010-01-01

... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Definitions § 51.319 Seriously deformed. “Seriously deformed” means that the...

7 CFR 319.73-1 - Definitions.

Science.gov (United States)

2010-01-01

..., DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Coffee § 319.73-1 Definitions. Administrator. The.... Any individual authorized by the Administrator to enforce this subpart. Sample. Unroasted coffee not for commercial resale. Intended use includes, but is not limited to, evaluation, testing, or market...

Project W-320, waste retrieval sluicing system: BIO/SER implementation matrices

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This document provides verification that the safety related commitments specified in HNF-SD-WM-810-001, Addendum 1 for the Waste Retrieval Sluicing System, Project W-320 and Project W-320 Safety Evaluation Report (SER), have been implemented in the project hardware, procedures and administrative controls. Four appendices include matrices which show where the 810 commitments are implemented for limiting conditions of operation and surveillance requirements controls, administrative controls, defense-in-depth controls and controls discussed in 810 Addendum 1. A fifth appendix includes the implementation of Project W-320 SER issues and provisions

7 CFR 1940.320 - Preparing EISs.

Science.gov (United States)

2010-01-01

... REGULATIONS (CONTINUED) GENERAL Environmental Program § 1940.320 Preparing EISs. (a) Responsibility. Whenever... implementation of the State's environmental impact analysis requirement, if one has been enacted or promulgated... of the natural and social sciences and the environmental design arts. The disciplines of the...

7 CFR 319.8-16 - Importation into United States of cotton and covers exported therefrom.

Science.gov (United States)

2010-01-01

... covers exported therefrom. (a) Cotton and covers grown, produced, or handled in the United States and... 7 Agriculture 5 2010-01-01 2010-01-01 false Importation into United States of cotton and covers exported therefrom. 319.8-16 Section 319.8-16 Agriculture Regulations of the Department of Agriculture...

5 CFR 319.302 - Individual qualifications.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Individual qualifications. 319.302... Individual qualifications. Agency heads are delegated authority to approve the qualifications of individuals appointed to SL and ST positions. The agency head must determine that the individual meets the...

7 CFR 319.74-1 - Definitions.

Science.gov (United States)

2010-01-01

... Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Cut Flowers § 319.74-1 Definitions. Administrator. The Administrator of the Animal and Plant Health Inspection Service, United States Department of Agriculture, or any...

9 CFR 319.100 - Corned beef.

Science.gov (United States)

2010-01-01

... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Cured Meats, Unsmoked and Smoked § 319.100... finished product, excluding cure, salt, and flavoring material, shall not exceed 70 percent of the fresh...

5 CFR 319.301 - Qualifications standards.

Science.gov (United States)

2010-01-01

... 319.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EMPLOYMENT... specialized experience in, or closely related to, the field in which the candidate will work. At least 1 year of this experience must have been in planning and executing difficult programs of national...

7 CFR 319.56-25 - Papayas from Central America and Brazil.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Papayas from Central America and Brazil. 319.56-25... § 319.56-25 Papayas from Central America and Brazil. The Solo type of papaya may be imported into the... shipment to the United States in one of the following locations: (1) Brazil: State of Espirito Santo; all...

32 CFR 700.320 - The Civilian Executive Assistants.

Science.gov (United States)

2010-07-01

... the Navy. (b) Each Civilian Executive Assistants, within his or her assigned area of responsibility... 32 National Defense 5 2010-07-01 2010-07-01 false The Civilian Executive Assistants. 700.320... of the Navy The Office of the Secretary of the Navy/the Civilian Executive Assistants § 700.320 The...

31 CFR 575.320 - U.S. financial institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. financial institution. 575.320... § 575.320 U.S. financial institution. The term U.S. financial institution means any U.S. person.... This term includes those branches, offices and agencies of foreign financial institutions which are...

7 CFR 319.41-2 - Application for permits.

Science.gov (United States)

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION... importation of any of the articles specified in § 319.41-1(b), shall first make application to the Plant Protection and Quarantine Programs for a permit, stating in the application the name and address of the...

31 CFR 537.320 - U.S. financial institution.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false U.S. financial institution. 537.320... Definitions § 537.320 U.S. financial institution. The term U.S. financial institution means any U.S. entity.... This term includes those branches, offices and agencies of foreign financial institutions that are...

46 CFR 185.320 - Steering gear, controls, and communication system tests.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Steering gear, controls, and communication system tests. 185.320 Section 185.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.320 Steering...

Characterizing the Resolved M6 Dwarf Twin LP 318-218AB

Science.gov (United States)

Moreno Hilario, Elizabeth; Burgasser, Adam J.; Bardalez Gagliuffi, Daniella; Tamiya, Tomoki

2017-01-01

The lowest-mass stars and brown dwarfs are among the most common objects in the Milky Way Galaxy, but theories of their formation and evolution remain poorly constrained. Binary systems are important for understanding the formation of these objects and for making direct orbit and mass measurements to validate evolutionary theories. We report the discovery of LP 318-218, a high proper motion late M dwarf, as a near equal-brightness binary system with a separation of 0.72 arcseconds. Resolved near-infrared spectroscopy confirms the components as nearly identical M6 twins. We using our resolved photometry and spectroscopy to estimate the distance, projected separation and tangential velocity of the system, and confirm common proper motion. We also perform atmosphere model fits to the resolved spectra to assess their physical properties. We place LP 318-218 in context with other widely-separated late M dwarf binaries.

7 CFR 319.24-1 - Applications for permits for importation of corn.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Applications for permits for importation of corn. 319... PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Corn Diseases Regulations Governing Entry of Indian Corn Or Maize § 319.24-1 Applications for permits for importation of...

7 CFR 319.8-18 - Samples.

Science.gov (United States)

2010-01-01

..., DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Foreign Cotton and Covers Miscellaneous Provisions § 319... requirements of this subpart, and which were exported from the United States, may be entered into the United... of cottonseed or seed cotton may be entered subject to the conditions and requirements provided in...

320-detector row CT coronary angiography in patients with arrhythmia

International Nuclear Information System (INIS)

Lu Li; Zhang Zhaoqi; Xu Lei; Yang Lin

2011-01-01

Objective: To evaluate the feasibility of CT coronary angiography (CTCA) in patients with arrhythmia using 320-detector row CT. Methods: Thirty-one patients with persistent atrial fibrillation and 8 patients with premature ventricular contraction were enrolled in this study. All patients underwent 320- detector row CTCA. CT image quality was evaluated with 4-point grading scale by two radiologists. Inter- observer agreement was evaluated by Kappa statistics. The radiation dose was calculated. Results: In total 510 coronary segments, 496 (97.2%) segments met diagnostic standard. The mean effective dose was (12.7±4.8) mSv in this study. There was a good agreement in image quality scoring between the two reviewers (Kappa = 0.72). Conclusion: 320-detector row CTCA is feasible in patients with atrial fibrillation and premature ventricular contraction. Arrhythmia may not be considered as a contraindication to CTCA. (authors)

320-row detector computed tomography angiography findings of a case with multiple

International Nuclear Information System (INIS)

Akay, S.; Bozlar, U.; Demirkol, S.; Tasar, M.

2012-01-01

Full text: Introduction: Computed tomography angiography (CTA) with three-dimensional imaging capability is a very reliable imaging modality for the evaluation of the coronary arteries. Objectives and tasks: To discuss the 320-row detector CTA findings of a case with multiple coronary artery course anomaly. Materials and methods: A 46-year-old man with palpitation, admitted to Cardiology department of our hospital. On electrocardiography, polymorphic ventricular early beats were observed. The patient was referred to Radiology department for CTA examination in terms of probable coronary artery anomaly. Results: On CTA, left main coronary artery was short. The bridging causes nearly 75% luminal stenosis was observed in the middle part of left descending artery. Circumflex artery was continuing as the first obtuse margin and this branch was separating to four branches in the middle part. They were coursing subepicardially in the middle and distal part. Right main coronary artery has also subepicardial course in its middle and distal part. Conclusion: Myocardial bridging is not a rare situation in routine clinical practice. But bridging in all of the three coronary arteries is very uncommon. Multidetector CTA is an effective and non-invasive imaging modality for understanding the normal anatomy and detecting the congenital anomalies of the coronary arteries

Operational test report - Project W-320 cathodic protection systems

International Nuclear Information System (INIS)

Bowman, T.J.

1998-01-01

Washington Administrative Code (WAC) 173-303-640 specifies that corrosion protection must be designed into tank systems that treat or store dangerous wastes. Project W-320, Waste Retrieval Sluicing System (WRSS), utilizes underground encased waste transfer piping between tanks 241-C-106 and 241-AY-102. Corrosion protection is afforded to the encasements of the WRSS waste transfer piping through the application of earthen ionic currents onto the surface of the piping encasements. Cathodic protection is used in conjunction with the protective coatings that are applied upon the WRSS encasement piping. WRSS installed two new two rectifier systems (46 and 47) and modified one rectifier system (31). WAC 173-303-640 specifies that the proper operation of cathodic protection systems must be confirmed within six months after initial installation. The WRSS cathodic protection systems were energized to begin continuous operation on 5/5/98. Sixteen days after the initial steady-state start-up of the WRSS rectifier systems, the operational testing was accomplished with procedure OTP-320-006 Rev/Mod A-0. This operational test report documents the OTP-320-006 results and documents the results of configuration testing of integrated piping and rectifier systems associated with the W-320 cathodic protection systems

45 CFR 149.320 - Universe of claims that must be submitted.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

48 CFR 319.202-2 - Locating small business sources.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 319.202-2 Locating small business sources. (a) OPDIVs shall foster, to the extent practicable, maximum participation by small businesses in HHS acquisitions...

Comparison in myelography between iodixanol 270 and 320 mgI/ml and iotrolan 300 mgI/ml: a multicentre, randomised, parallel-group, double-blind, phase III trial

International Nuclear Information System (INIS)

Palmers, Yvan; Kuhn, Fritz-Peter; Petersen, Dirk; De Greef, Danielle

2002-01-01

The objective of the trial was to compare the safety and efficacy of the non-ionic, dimeric, isotonic contrast medium iodixanol (Visipaque 270 and 320 mgI/ml) with those of iotrolan (Isovist 300 mgI/ml) in myelography. After lumbar or cervical puncture, 315 patients were examined in a multicentre, double-blind, randomised, comparative myelography study. Image quality, changes in vital signs, immediate and delayed adverse events were registered. There was a tendency for better images with iodixanol 320 than with iodixanol 270 and iotrolan 300, but the overall quality was good or excellent with all products. The frequency of patients reporting adverse events and headache varied much across centres, but there was no statistically significant difference between the contrast media. The incidence of events was higher after lumbar puncture than after cervical puncture, in women rather than in men, and after puncture with a 22-gauge (G) bevel-tipped needle compared with a 24 G Sprotte needle. The frequency of headache did not correlate with the absence of pathology. The higher iodine concentration in iodixanol 320 could be an advantage for film quality. When compared with iotrolan 300, iodixanol 320 and 270 give similar incidences of adverse events, including headache. (orig.)

Project W-320 ALARA Plan

International Nuclear Information System (INIS)

Harty, W.M.

1995-01-01

This supporting document establishes the As Low As Reasonable Achievable (ALARA) Plan to be followed during Sluicing Project W-320 design and construction activities to minimize personnel exposure to radiation and hazardous materials

Project W-320 ALARA Plan

Energy Technology Data Exchange (ETDEWEB)

Harty, W.M.

1995-06-06

This supporting document establishes the As Low As Reasonable Achievable (ALARA) Plan to be followed during Sluicing Project W-320 design and construction activities to minimize personnel exposure to radiation and hazardous materials.

7 CFR 319.24-4 - Notice of arrival of corn by permittee.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Notice of arrival of corn by permittee. 319.24-4... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Corn Diseases Regulations Governing Entry of Indian Corn Or Maize § 319.24-4 Notice of arrival of corn by permittee. Immediately upon...

7 CFR 319.40-3 - General permits; articles that may be imported without a specific permit; articles that may be...

Science.gov (United States)

2010-01-01

... treatments that achieve this specification through the use of steam, hot water, or dry heat; or, (ii... the port of first arrival may order the immediate reexport of regulated wood packaging material that... of any port of first arrival procedures required by § 319.40-9 of this part. (4) Exception for...

Team play with a powerful and independent agent: operational experiences and automation surprises on the Airbus A-320

Science.gov (United States)

Sarter, N. B.; Woods, D. D.

1997-01-01

Research and operational experience have shown that one of the major problems with pilot-automation interaction is a lack of mode awareness (i.e., the current and future status and behavior of the automation). As a result, pilots sometimes experience so-called automation surprises when the automation takes an unexpected action or fails to behave as anticipated. A lack of mode awareness and automation surprises can he viewed as symptoms of a mismatch between human and machine properties and capabilities. Changes in automation design can therefore he expected to affect the likelihood and nature of problems encountered by pilots. Previous studies have focused exclusively on early generation "glass cockpit" aircraft that were designed based on a similar automation philosophy. To find out whether similar difficulties with maintaining mode awareness are encountered on more advanced aircraft, a corpus of automation surprises was gathered from pilots of the Airbus A-320, an aircraft characterized by high levels of autonomy, authority, and complexity. To understand the underlying reasons for reported breakdowns in human-automation coordination, we also asked pilots about their monitoring strategies and their experiences with and attitude toward the unique design of flight controls on this aircraft.

7 CFR 319.73-3 - Conditions for transit movement of certain products through Puerto Rico or Hawaii.

Science.gov (United States)

2010-01-01

... through Puerto Rico or Hawaii. 319.73-3 Section 319.73-3 Agriculture Regulations of the Department of... or Hawaii. (a) Mail. Samples of unroasted coffee that are transiting Hawaii or Puerto Rico en route.... These samples must be returned to origin or forwarded to a destination outside Hawaii or Puerto Rico in...

MicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6.

Science.gov (United States)

Tadano, Toshihiro; Kakuta, Yoichi; Hamada, Shin; Shimodaira, Yosuke; Kuroha, Masatake; Kawakami, Yoko; Kimura, Tomoya; Shiga, Hisashi; Endo, Katsuya; Masamune, Atsushi; Takahashi, Seiichi; Kinouchi, Yoshitaka; Shimosegawa, Tooru

2016-07-15

To investigate the microRNA (miRNA) expression during histological progression from colorectal normal mucosa through adenoma to carcinoma within a lesion. Using microarray, the sequential changes in miRNA expression profiles were compared in colonic lesions from matched samples; histologically, non-neoplastic mucosa, adenoma, and submucosal invasive carcinoma were microdissected from a tissue sample. Cell proliferation assay was performed to observe the effect of miRNA, and its target genes were predicted using bioinformatics approaches and the expression profile of SW480 transfected with the miRNA mimics. mRNA and protein levels of the target gene in colon cancer cell lines with a mimic control or miRNA mimics were measured using qRT-PCR and Western blotting. The expression levels of miRNA and target gene in colorectal tissue samples were also measured. Microarray analysis identified that the miR-320 family, including miR-320a, miR-320b, miR-320c, miR-320d and miR-320e, were differentially expressed in adenoma and submucosal invasive carcinoma. The miR-320 family, which inhibits cell proliferation, is frequently downregulated in colorectal adenoma and submucosal invasive carcinoma tissues. Seven genes including CDK6 were identified to be common in the results of gene expression array and bioinformatics analyses performed to find the target gene of the miR-320 family. We confirmed that mRNA and protein levels of CDK6 were significantly suppressed in colon cancer cell lines with miR-320 family mimics. CDK6 expression was found to increase from non-neoplastic mucosa through adenoma to submucosal invasive carcinoma tissues and showed an inverse correlation with miR-320 family expression. MiR-320 family affects colorectal tumor proliferation by targeting CDK6, plays important role in its growth, and is considered to be a biomarker for its early detection.

27 CFR 19.318 - Addition of caramel to rum or brandy and addition of oak chips to spirits.

Science.gov (United States)

2010-04-01

... or brandy and addition of oak chips to spirits. 19.318 Section 19.318 Alcohol, Tobacco Products and... PLANTS Production § 19.318 Addition of caramel to rum or brandy and addition of oak chips to spirits. Caramel possessing no material sweetening properties may be added to rum or brandy on bonded premises...

9 CFR 319.761 - Potted meat food product and deviled meat food product.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Potted meat food product and deviled meat food product. 319.761 Section 319.761 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY...

MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

DEFF Research Database (Denmark)

Vishnubalaji, Radhakrishnan; Hamam, Rimi; Shijun, Yue

2016-01-01

Colorectal cancer (CRC) is the third most common cancer causing high mortality rates world-wide. Delineating the molecular mechanisms leading to CRC development and progression, including the role of microRNAs (miRNAs), are currently being unravelled at a rapid rate. Here, we report frequent down...... for the miR-320/SOX4/FOXM1/FOXQ1 axes in promoting CRC development and progression and suggest targeting those networks as potential therapeutic strategy for CRC....... mice. Global gene expression analysis in CRC cells over-expressing miR-320c, combined with in silico prediction identified 84 clinically-relevant potential gene targets for miR-320 in CRC. Using a series of biochemical assays and functional validation, SOX4, FOXM1, and FOXQ1 were validated as novel...... gene targets for the miR-320 family. Inverse correlation between the expression of miR-320 members with SOX4, FOXM1, and FOXQ1 was observed in primary CRC patients' specimens, suggesting that these genes are likely bona fide targets for the miR-320 family. Interestingly, interrogation of the expression...

New alternatives for laser vaporization of the prostate: experimental evaluation of a 980-, 1,318- and 1,470-nm diode laser device.

Science.gov (United States)

Wezel, Felix; Wendt-Nordahl, Gunnar; Huck, Nina; Bach, Thorsten; Weiss, Christel; Michel, Maurice Stephan; Häcker, Axel

2010-04-01

Several diode laser systems were introduced in recent years for the minimal-invasive surgical therapy of benign prostate enlargement. We investigated the ablation capacities, hemostatic properties and extend of tissue necrosis of different diode lasers at wavelengths of 980, 1,318 and 1,470 nm and compared the results to the 120 W GreenLight HPS laser. The laser devices were evaluated in an ex vivo model using isolated porcine kidneys. The weight difference of the porcine kidneys after 10 min of laser vaporization defined the amount of ablated tissue. Blood loss was measured in blood-perfused kidneys following laser vaporization. Histological examination was performed to assess the tissue effects. The side-firing 980 and 1,470 nm diode lasers displayed similar ablative capacities compared to the GreenLight HPS laser (n.s.). The 1,318-nm laser, equipped with a bare-ended fiber, reached a higher ablation rate compared to the other laser devices (each P laser with a bare-ended fiber reached the highest rate compared to the side-firing devices (each P diode lasers showed superior hemostatic properties compared to the GreenLight HPS laser (each P laser), respectively. The diode lasers offered similar ablative capacities and improved hemostatic properties compared to the 120 W GreenLight HPS laser in this experimental ex vivo setting. The higher tissue penetration of the diode lasers compared to the GreenLight HPS laser may explain improved hemostasis.

9 CFR 319.141 - Fresh pork sausage.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Fresh pork sausage. 319.141 Section... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Sausage Generally: Fresh...

9 CFR 319.160 - Smoked pork sausage.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Smoked pork sausage. 319.160 Section... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Uncooked, Smoked Sausage...

50 CFR 648.320 - Skate FMP review and monitoring.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Skate FMP review and monitoring. 648.320 Section 648.320 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES OF THE NORTHEASTERN UNITED STATES Management Measures for the NE Skate Complex Fisheries §...

Project W-320, 241-C-106 sluicing: Construction specification W-320-C2

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits

Project W-320, 241-C-106 sluicing: Construction specification W-320-C2

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-20

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits.

Project W-320, 241-C-106 sluicing: Construction specification W-320-C6

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits

Project W-320, 241-C-106 sluicing: Construction specification W-320-C5

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits

Project W-320, 241-C-106 sluicing: Construction specification W-320-C7

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits

Project W-320, 241-C-106 sluicing: Construction specification W-320-C5

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-20

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits.

Project W-320, 241-C-106 sluicing: Construction specification W-320-C7

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-20

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits.

Project W-320, 241-C-106 sluicing: Construction specification W-320-C6

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-20

This supporting document has been prepared to make the construction specifications for Project W-320 readily available. Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits.

Calculation of dose in anthropomorphic dummies ICRP 110 simulation of protocols overall for a team of 320 sections TC

International Nuclear Information System (INIS)

Cros Torrents, M.; Geleijns, J.; Salvador Artells, M.

2013-01-01

The objective of this study is to carry out, using a program of simulation Monte Carlo, an estimate of the dose received in anthropomorphic mannequins voxelized in tests of four protocols established for the Aquilion ONE General acquiring in conical beam of 320 X 0, 5 mm. Finally, will be obtained factors of conversion between values of product dose (DLP) length and effective doses for each protocol. (Author)

77 FR 42952 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2012-07-23

... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318-112 and -121 airplanes; Model A319-111, -112, -115, - 132, and -133 airplanes; Model... MCAI states: During structural part assembly in Airbus production line, some nuts Part Number (P/N...

7 CFR 51.320 - Diameter.

Science.gov (United States)

2010-01-01

... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Definitions § 51.320 Diameter. When measuring for minimum size, “diameter...

LCX: Proposal for a low-cost commercial transport

Science.gov (United States)

Hartman, Troy; Hayatdavoudi, Maziar; Hettinga, Joel; Hooper, Matt; Nguyen, Phong

1994-01-01

The LCX has been developed in response to a request for proposal for an aircraft with 153 passenger capacity and a range of 3000 nautical miles. The goals of the LCX are to provide an aircraft which will achieve the stated mission requirements at the lowest cost possible, both for the manufacturer and the operator. Low cost in this request is defined as short and long term profitability. To achieve this objective, modern technologies attributing to low-cost operation without greatly increasing the cost of manufacturing were employed. These technologies include hybrid laminar flow control and the use of developing new manufacturing processes and philosophies. The LCX will provide a competitive alternative to the use of the Airbus A319/320/321 and the Boeing 737 series of aircraft. The LCX has a maximum weight of 150,000 lb. carried by a wing of 1140 ft(exp 2) and an aspect ratio of 10. The selling price of the LCX is 31 million in 1994 US dollars.

78 FR 14029 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2013-03-04

...-0096; Directorate Identifier 2012-NM-143-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A318-112, A319-111... Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte, 31707 Blagnac Cedex, France; telephone...

Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography

Energy Technology Data Exchange (ETDEWEB)

Bhardwaj, Anshul [Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107 (United States); Casjens, Sherwood R. [University of Utah School of Medicine, Salt Lake City, UT 84112 (United States); Cingolani, Gino, E-mail: gino.cingolani@jefferson.edu [Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107 (United States)

2014-02-01

This study presents the crystal structure of a ∼320 Å long protein fiber generated by in-frame extension of its repeated helical coiled-coil core. Protein fibers are widespread in nature, but only a limited number of high-resolution structures have been determined experimentally. Unlike globular proteins, fibers are usually recalcitrant to form three-dimensional crystals, preventing single-crystal X-ray diffraction analysis. In the absence of three-dimensional crystals, X-ray fiber diffraction is a powerful tool to determine the internal symmetry of a fiber, but it rarely yields atomic resolution structural information on complex protein fibers. An 85-residue-long minimal coiled-coil repeat unit (MiCRU) was previously identified in the trimeric helical core of tail needle gp26, a fibrous protein emanating from the tail apparatus of the bacteriophage P22 virion. Here, evidence is provided that an MiCRU can be inserted in frame inside the gp26 helical core to generate a rationally extended fiber (gp26-2M) which, like gp26, retains a trimeric quaternary structure in solution. The 2.7 Å resolution crystal structure of this engineered fiber, which measures ∼320 Å in length and is only 20–35 Å wide, was determined. This structure, the longest for a trimeric protein fiber to be determined to such a high resolution, reveals the architecture of 22 consecutive trimerization heptads and provides a framework to decipher the structural determinants for protein fiber assembly, stability and flexibility.

Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography

International Nuclear Information System (INIS)

Bhardwaj, Anshul; Casjens, Sherwood R.; Cingolani, Gino

2014-01-01

This study presents the crystal structure of a ∼320 Å long protein fiber generated by in-frame extension of its repeated helical coiled-coil core. Protein fibers are widespread in nature, but only a limited number of high-resolution structures have been determined experimentally. Unlike globular proteins, fibers are usually recalcitrant to form three-dimensional crystals, preventing single-crystal X-ray diffraction analysis. In the absence of three-dimensional crystals, X-ray fiber diffraction is a powerful tool to determine the internal symmetry of a fiber, but it rarely yields atomic resolution structural information on complex protein fibers. An 85-residue-long minimal coiled-coil repeat unit (MiCRU) was previously identified in the trimeric helical core of tail needle gp26, a fibrous protein emanating from the tail apparatus of the bacteriophage P22 virion. Here, evidence is provided that an MiCRU can be inserted in frame inside the gp26 helical core to generate a rationally extended fiber (gp26-2M) which, like gp26, retains a trimeric quaternary structure in solution. The 2.7 Å resolution crystal structure of this engineered fiber, which measures ∼320 Å in length and is only 20–35 Å wide, was determined. This structure, the longest for a trimeric protein fiber to be determined to such a high resolution, reveals the architecture of 22 consecutive trimerization heptads and provides a framework to decipher the structural determinants for protein fiber assembly, stability and flexibility

Simulating deforestation and carbon loss in Amazonia: impacts in Brazil's Roraima state from reconstructing Highway BR-319 (Manaus-Porto Velho).

Science.gov (United States)

Barni, Paulo Eduardo; Fearnside, Philip Martin; Graça, Paulo Maurício Lima de Alencastro

2015-02-01

Reconstruction of Highway BR-319 (Manaus-Porto Velho) would allow for access from the "arc of deforestation" in the southern part of Brazil's Amazon region to vast blocks of forests in central and northern Amazonia. Building roads is known to be a major driver of deforestation, allowing entry of squatters, and other actors. Rather than deforestation along the highway route, here we consider the road's potential for stimulating deforestation in a separate location, approximately 550 km north of BR-319's endpoint in Manaus. Reconstructing BR-319 has great potential impact to start a new wave of migration to this remote region. The southern portion of the state of Roraima, the focus of our study, is already connected to Manaus by Highway BR-174. We modeled deforestation in southern Roraima and simulated carbon emissions between 2007 and 2030 under four scenarios. Simulations used the AGROECO model in DINAMICA-EGO © software. Two scenarios were considered with reconstruction of BR-319 and two without this road connection. For each of the two possibilities regarding BR-319, simulations were developed for (1) a "conservation" (CONSERV) scenario that assumes the creation of a series of protected areas, and (2) a "business-as-usual" (BAU) scenario that assumes no additional protected areas. Results show that by 2030, with BR-319 rebuilt, deforestation carbon emissions would increase between 19% (CONSERV) and 42% (BAU) over and above those corresponding to no-road scenarios.

48 CFR 319.705-5 - Awards involving subcontracting plans.

Science.gov (United States)

2010-10-01

... SERVICES SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Subcontracting With Small Business, Small Disadvantaged Business, and Women-Owned Small Business Concerns 319.705-5 Awards involving subcontracting plans...

7 CFR 319.37-12 - Prohibited articles accompanying restricted articles.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Prohibited articles accompanying restricted articles... Stock, Plants, Roots, Bulbs, Seeds, and Other Plant Products 1,2 § 319.37-12 Prohibited articles accompanying restricted articles. A restricted article for importation into the United States shall not be...

33 CFR 209.320 - Policy on release of commercial statistics.

Science.gov (United States)

2010-07-01

... statistics. 209.320 Section 209.320 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE... statistics. The collection of commercial statistics pertaining to rivers, harbors, and waterways, and annual... waterway statistics. In case Federal or State agencies or local interests request other than general...

Modeling of the influence of coarsening on viscoplastic behavior of a 319 foundry aluminum alloy

International Nuclear Information System (INIS)

Martinez, R.; Russier, V.; Couzinié, J.P.; Guillot, I.; Cailletaud, G.

2013-01-01

Both metallurgical and mechanical behaviors of a 319 foundry aluminum alloy have been modeled by means of a multiscale approach. The nano-scale, represented by the coarsening of Al 2 Cu precipitates, has been modeled according to the Lifshitz–Slyozov–Wagner (LSW) law in a range of temperature going from 23 °C to 300 °C up to 1000 h aging time. Results were then compared to transmission electron microscope (TEM) observations and are in good agreement with the experimental measurements. The model allows us to know the critical radius, the volume fraction and the number of particles per μm 3 in a α-phase representative volume element (RVE). The increase in yield stress generated by the interaction of dislocations with precipitates, lattice and solid solution, is modeled on the microscale. The yield stress becomes thus a function of the precipitation state, and is time/temperature dependent. These two models were then combined into a mechanical macroscale model in order to represent the Low Cycle Fatigue (LCF) behavior of the material. An elasto-viscoplastic law has been used and all the material parameters were experimentally determined with LCF stress/strain loops for the first cycle and for the mechanical steady state. The simulation results are in good agreement with the experiments.

Animal model for evaluation of topical photoprotection against ultraviolet A (320-380 nm) radiation

International Nuclear Information System (INIS)

Chew, S.; DeLeo, V.A.; Harber, L.C.

1987-01-01

Recent studies reporting UVA (ultraviolet A radiation 320-380 nm) as an integral part of the cumulative sun-induced damage in human skin have prompted an interest in developing effective UVA photoprotective agents. The development of such compounds has been impeded by the absence of a clinically relevant animal model for evaluating their efficacy. This report describes the development and use of such a laboratory animal system. Selected concentrations of oxybenzone (2-hydroxy-4-methoxybenzophenone) in vehicle (0.1% to 6%) or vehicle alone were applied to the depilated dorsal skin of 30 Hartley strain female albino guinea pigs. The skin was irradiated with solar simulated UVA from a xenon light source. Acute radiation-induced damage was assayed by erythema grading and inhibition of [ 3 H]thymidine incorporation into epidermal DNA. Data from erythema grading studies indicated that a significant degree of photoprotection was achieved with 6%, 3%, and 1% solutions of benzophenone compared with the control vehicle; the 6% solution was significantly more photoprotective than the 3% and 1% solutions. A 6% solution afforded significant photoprotection when assayed by [ 3 H]thymidine incorporation

miR-320 enhances the sensitivity of human colon cancer cells to chemoradiotherapy in vitro by targeting FOXM1

Energy Technology Data Exchange (ETDEWEB)

Wan, Lu-Ying; Deng, Jun; Xiang, Xiao-Jun; Zhang, Ling; Yu, Feng; Chen, Jun; Sun, Zhe; Feng, Miao; Xiong, Jian-Ping, E-mail: jpxiong@medmail.com.cn

2015-02-06

Highlights: • miR-320 plays a significant role in chemoresistance. • This role might be attribute to targeting FOXM1. • The Wnt/β-catenin pathway also involves in this chemotherapy sensitivity. - Abstract: miR-320 expression level is found to be down-regulated in human colon cancer. To date, however, its underlying mechanisms in the chemo-resistance remain largely unknown. In this study, we demonstrated that ectopic expression of miR-320 led to inhibit HCT-116 cell proliferation, invasion and hypersensitivity to 5-Fu and Oxaliplatin. Also, knockdown of miR-320 reversed these effects in HT-29 cells. Furthermore, we identified an oncogene, FOXM1, as a direct target of miR-320. In addition, miR-320 could inactive the activity of Wnt/β-catenin pathway. Finally, we found that miR-320 and FOXM1 protein had a negative correlation in colon cancer tissues and adjacent normal tissues. These findings implied that miR-320–FOXM1 axis may overcome chemo-resistance of colon cancer cells and provide a new therapeutic target for the treatment of colon cancer.

7 CFR 319.74-3 - Importations by the Department.

Science.gov (United States)

2010-01-01

... INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Cut Flowers § 319.74-3 Importations by the Department. The U.S. Department of Agriculture may import cut flowers for experimental or...

Three family members with elevated plasma cobalamin, transcobalamin and soluble transcobalamin receptor (sCD320)

DEFF Research Database (Denmark)

Hoffmann-Lücke, Elke; Arendt, Johan F B; Nissen, Peter H

2013-01-01

deficiency were found. DNA sequencing of the TCN2 gene revealed several known polymorphisms not associated with highly elevated transcobalamin levels. Upon gel filtration, sCD320 eluted as a larger molecule than previously reported. By incubation with anti-transcobalamin antibodies, we precipitated both...... transcobalamin and part of sCD320. CONCLUSIONS: The high cobalamin levels were mainly explained by high levels of holoTC, possibly caused by complex formation with its soluble receptor, sCD320. The family occurrence points to a genetic explanation....

Regulation of Pattern Formation and Gene Amplification During Drosophila Oogenesis by the miR-318 microRNA

DEFF Research Database (Denmark)

Ge, Wanzhong; Deng, Qiannan; Guo, Ting

2015-01-01

Pattern formation during epithelial development requires the coordination of multiple signaling pathways. Here, we investigate the functions of an ovary-enriched miRNA, miR-318, in epithelial development during Drosophila oogenesis. miR-318 maternal loss-of-function mutants were female sterile...... and laid eggs with abnormal morphology. Removal of miR-318 disrupted the dorsal-anterior follicle cell patterning, resulting in abnormal dorsal appendages. miR-318 mutant females also produced thin and fragile eggshells, due to impaired chorion gene amplification. We provide evidence that the ecdysone......RNAs in maintaining cell fate and promoting the developmental transition in the female follicular epithelium....

Proposal to negotiate, without competitive tendering, a contract for the manufacture, testing and delivery of 320 cryogenic helium mass flowmeters for the LHC

CERN Document Server

2001-01-01

This document concerns the manufacture, testing and delivery of 320 cryogenic helium mass flowmeters for the LHC. Following a market survey (MS-2602/LHC/LHC) carried out amoung 37 firms in twelve Member States and six firms in two non-Member States, a price enquiry for qualifying prototypes was sent on 20 November 1998 to nine selected firms and the received prototypes were evaluated. As a result of this process a request for quotation was sent to one firm The Finance Committee is invited to agree to the negotiation of a contract with the firm EMERSON PROCESS MANAGEMENT/FISHER-ROSEMOUNT (CH), without competitive tendering, for the manufacture, testing and delivery of 320 cryogenic helium mass flowmeters for an amount of 1 804 840 Swiss francs, not subject to revision, with options for up to 10 additional cryogenic helium mass flowmeters and an extension of the guarantee period to five years for all units for an amount of 219 090 Swiss francs, not subject to revision, bringing the total amount to 2 023 930 Swi...

78 FR 54482 - Eastern States: Filing of Plats of Survey

Science.gov (United States)

2013-09-04

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLES956000-L14200000-BK0000] Eastern States... the Federal Register, Volume 78, Number 2, on pages 318-319 a notice entitled ``Eastern States: Filing... resurvey of a portion of the Qualla Indian Boundary, land held in trust for the Eastern Band of Cherokee...

The certification of hydrogen in titanium. CRM No. 318

International Nuclear Information System (INIS)

Vandendriessche, S.; Marchandise, H.; Vandecasteele, C.

1987-01-01

This report describes the work done to certify the hydrogen content in a batch of 28 kg of commercial unalloyed titanium. The homogeneity of the three original sheets of metals was demonstrated. Samples were analysed by 10 laboratories using hydrogen extraction and thermal conductivity measurement and by 2 laboratories using a nuclear resonance reaction technique, but the accuracy of the latter was insufficient for a certification. On the basis of the measurements in 8 laboratories using extraction techniques, the hydrogen mass fraction in the titanium (CRM 318) is certified to be (12.2 +/- 0.8) ug/g

9 CFR 319.721 - Fluid extract of meat.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Fluid extract of meat. 319.721 Section... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Soups, Soup Mixes...

The soluble transcobalamin receptor (sCD320) in relation to Alzheimer's disease and cognitive scores

DEFF Research Database (Denmark)

Abuyaman, Omar; Combrinck, Marc; Smith, A David

2017-01-01

The soluble transcobalamin receptor (sCD320) is present in cerebrospinal fluid and correlates with the dementia-related biomarkers phospho-tau and total-tau. Here we present data on the relation of sCD320 to Alzheimer's disease and scores of cognitive tests. Lumbar cerebrospinal fluid samples from...... 42 pathologically-confirmed cases of Alzheimer's disease and 25 non-demented controls were analyzed for sCD320 employing an in-house ELISA. The participants' cognitive functions were tested using the Cambridge Cognition Examination (CAMCOG) and the Mini-Mental State Examination (MMSE...... be employed as a biomarker for differentiating Alzheimer dementia patients from controls. Further studies are warranted to explore the non-linear correlations between sCD320 and scores of cognitive function....

7 CFR 4290.320 - Contents of comprehensive business plan.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Contents of comprehensive business plan. 4290.320... comprehensive business plan. (a) Plan for Developmental Venture Capital investing. The Applicant must describe... of the Applicant's business plan. ...

7 CFR 319.56-43 - Baby corn and baby carrots from Zambia.

Science.gov (United States)

2010-01-01

... § 319.56-43 Baby corn and baby carrots from Zambia. (a) Immature, dehusked “baby” sweet corn (Zea mays L... consignments only. (b) Immature “baby” carrots (Daucus carota L. ssp. sativus) for consumption measuring 10 to...

9 CFR 319.311 - Chow mein vegetables with meat, and chop suey vegetables with meat.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Chow mein vegetables with meat, and chop suey vegetables with meat. 319.311 Section 319.311 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY...

7 CFR 319.74-4 - Costs and charges.

Science.gov (United States)

2010-01-01

... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Cut Flowers § 319.74-4 Costs and charges. The Animal and Plant Health Inspection Service, U.S. Department of Agriculture, will be responsible only for the costs of providing the services of an inspector during regularly assigned hours of duty...

Effect of Sb-Modification on the Microstructure and Mechanical Properties of Secondary Alloy 319

Directory of Open Access Journals (Sweden)

Medlen D.

2016-06-01

Full Text Available 319 alloy has been selected for the study in the present work due to its wide use in many applications. 319 alloy is used in automotive and aerospace industry for the complicated castings which must comply high strength requirements. In practice, the most common elements with the modifying effect are strontium, sodium and antimony. The addition of these elements leads to a change in the shape of eutectic silicon, resulting in an increase of the mechanical characteristics and the microstructure. An experimental program has been undertaken to explore the effect of antimony on chosen mechanical properties and the microstructure of investigated alloy. An analysis of the results of these experimental works is made in order to determine an optimum Sb (Al-10% Sb addition to produce material exhibiting desirable properties. Experimental works have showed that the addition of the Al-10% Sb results in similar or even higher mechanical properties than the conventional 319 alloy. Based on the carried out experiments the best combination of mechanical properties has been achieved by the addition of 2 000 ppm Al-10% Sb.

50 CFR 660.319 - Open access fishery gear identification and marking.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Open access fishery gear identification... COAST STATES West Coast Groundfish-Open Access Fisheries § 660.319 Open access fishery gear identification and marking. (a) Gear identification. (1) Open access fixed gear (longline, trap or pot, set net...

78 FR 51058 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2013-08-20

... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... certain Airbus Model A319 and A320 series airplanes. AD 2004-13-06 required repetitive detailed... and to allow extension of the interval between two consecutive inspections, Airbus validated an Eddy...

Cancerogenesis Risks between 64 and 320 Row Detector CT for Coronary CTA Screening

Directory of Open Access Journals (Sweden)

Atif N Khan

2014-01-01

Full Text Available Objectives: This study compares cancerogenesis risks posed by the 64 row detector and the 320 row detector computed tomography scanners used during coronary computed tomography angiography (CCTA following decennial screening guidelines. Material and Methods: Data of the radiation absorbed after CCTA by lung, thyroid, and female breast in patients between 50 and 70 years of age obtained from prior published literature for the 64 row CT scanner were compared with data from our study using 320 row detector CT scanner. Data from the 64 row and the 320 row detector CT scanners was used to determine lifetime attributable risks (LAR of cancer based on the biological effects of ionizing radiation (BEIR VII report. Results: The relative reduction of LAR (% for 50-, 60-, and 70-year-old patients undergoing scanning with the 320 row detector CT scanner was 30% lower for lung, and more than 50% lower for female breast when compared with results from 64 row detector CT scanner. The use of 320 row detector CT would result in a combined cumulative cancer incidence of less than 1/500 for breast in women and less than 1/1000 for lung in men; By comparison, this is much lower than other more common risk factors: 16-fold for lung cancer in persistent smokers, 2-fold for breast cancer with a first degree family member history of breast cancer, and 10-fold for thyroid cancer with a family member with thyroid cancer. Decennial screening would benefit at least 355,000 patients from sudden cardiac death each year, 94% of whom have significant coronary artery disease, with at least one stenosis >75%. LAR for thyroid cancer was negligible for both scanners. Conclusion: Lung and female breast LAR reductions with 320 row detector compared with 64 row detector CT are substantial, and the benefits would outweigh increased cancer risks with decennial screening in the age group of 50-70 years.

Parameters controlling the performance of AA319-type alloys Part II. Impact properties and fractography

International Nuclear Information System (INIS)

Li, Z.; Samuel, A.M.; Samuel, F.H.; Ravindran, C.; Doty, H.W.; Valtierra, S.

2004-01-01

The Charpy impact energy of Al-Si-Cu AA319-type alloys was measured in terms of the total absorbed energy. The Charpy specimens were machined from end-chilled castings to incorporate the effect of cooling rate on the impact properties. Unnotched specimens were used to increase the accuracy of the measurements, and to emphasize the effect of microstructure. The influence of the microconstituents on the impact strength was investigated by adding various alloying elements (i.e. Sr, Fe, and P) to the AA319 base alloy, and applying two different heat treatments (T5, and T6). The results show that strontium-modification enhances the impact properties, so that the Sr-modified AA319 alloy exhibits the highest impact properties compared to the base, and other alloys at any given dendrite arm spacing (DAS). The impact energy increases with increase in cooling rate, while iron, and phosphorus additions have a detrimental influence due, respectively, to the formation of β-Al 5 FeSi, and phosphorus oxide particles during solidification. T6 treatment assists in the even distribution, and dissolution of the microconstituents (including the block-like CuAl 2 particles) into the aluminum matrix. With more Cu available for strengthening during aging, the impact toughness is greatly enhanced. In the unmodified AA319 base alloy, crack initiation, and propagation occur mainly through Si-particle fracture, and the mechanism of void coalescence. In the Sr-modified, 1.2% Fe-containing 319 alloys, however, crack initiation takes place through fragmentation of β-Al 5 FeSi, Si, and CuAl 2 or Cu 2 FeAl 7 particles. Crack propagation occurs through cleavage of the β-Fe platelets, and fracture of the Cu-intermetallics, and brittle Si particles. Such samples exhibit very low impact energies

Project W-320, 241-C-106 sluicing: Civil/structural calculations. Volume 6

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-24

This supporting document has been prepared to make the FDNW calculations for Project W-320 readily retrievable. The purpose of this calculation is to conservatively estimate the weight of equipment and structures being added over Tank 241-C-106 as a result of Project W-320 and combine these weights with the estimated weights of existing structures and equipment as calculated in Attachment 1. The combined weights will be compared to the allowable live load limit to provide a preliminary assessment of loading conditions above Tank 241-C-106.

21 CFR 172.320 - Amino acids.

Science.gov (United States)

2010-04-01

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Special Dietary and Nutritional Additives § 172.320 Amino acids. The food additive amino acids may be safely used...

78 FR 9729 - Eastern States: Filing of Plat of Survey, North Carolina

Science.gov (United States)

2013-02-11

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLES956000-L14200000-BJ0000] Eastern States..., on pages 318 through 319 a notice entitled ``Eastern States: Filing of Plats of Survey''. In said... Boundary, lands held in trust for the Eastern Band of Cherokee Indians, Swain County, in the State of North...

HAT-TR-318-007: A Double-lined M Dwarf Binary with Total Secondary Eclipses Discovered by HATNet and Observed by K2

Science.gov (United States)

Hartman, J. D.; Quinn, S. N.; Bakos, G. Á.; Torres, G.; Kovács, G.; Latham, D. W.; Noyes, R. W.; Shporer, A.; Fulton, B. J.; Esquerdo, G. A.; Everett, M. E.; Penev, K.; Bhatti, W.; Csubry, Z.

2018-03-01

We report the discovery by the HATNet survey of HAT-TR-318-007, a P=3.34395390+/- 0.00000020 day period detached double-lined M dwarf binary with total secondary eclipses. We combine radial velocity (RV) measurements from TRES/FLWO 1.5 m and time-series photometry from HATNet, FLWO 1.2 m, BOS 0.8 m, and NASA K2 Campaign 5, to determine the masses and radii of the component stars: MA=0.448+/-0.011 M⊙N, MB=0.2721-0.0042+0.0041 M⊙N, RA=0.4548-0.0036+0.0035 R⊙N, and RB=0.2913-0.0024+0.0023 R⊙N. We obtained a FIRE/Magellan near-infrared spectrum of the primary star during a total secondary eclipse, and we use this to obtain disentangled spectra of both components. We determine spectral types of STA=M 3.71+/- 0.69 and STB=M 5.01+/- 0.73 and effective temperatures of Teff, A= 3190+/-110 K and Teff, B=3100+/- 110 K for the primary and secondary star, respectively. We also measure a metallicity of [Fe/H] = +0.298+/- 0.080 for the system. We find that the system has a small, but significant, nonzero eccentricity of 0.0136+/- 0.0026. The K2 light curve shows a coherent variation at a period of 3.41315-0.00032+0.00030 days, which is slightly longer than the orbital period, and which we demonstrate comes from the primary star. We interpret this as the rotation period of the primary. We perform a quantitative comparison between the Dartmouth stellar evolution models and the seven systems, including HAT-TR-318-007, that contain M dwarfs with 0.2 M⊙N< M< 0.5 M⊙N, have metallicity measurements, and have masses and radii determined to better than 5% precision. Discrepancies between the predicted and observed masses and radii are found for three of the systems.

29 CFR 778.318 - Productive and nonproductive hours of work.

Science.gov (United States)

2010-07-01

... Special Problems Effect of Failure to Count Or Pay for Certain Working Hours § 778.318 Productive and... Act; such nonproductive working hours must be counted and paid for. (b) Compensation payable for... which such nonproductive hours are properly counted as working time but no special hourly rate is...

Error-free 320 Gb/s simultaneous add-drop multiplexing

DEFF Research Database (Denmark)

Mulvad, Hans Christian Hansen; Oxenløwe, Leif Katsuo; Clausen, Anders

2007-01-01

We report on the first demonstration of error-free time-division add-drop multiplexing at 320 Gb/s. The add- and drop-operations are performed simultaneously in a non-linear optical loop mirror with only 100 m of highly non-linear fibre....

Detection of 320 Gb/s Nyquist OTDM by polarization-insensitive time-domain optical Fourier transformation

DEFF Research Database (Denmark)

Hu, Hao; Kong, Deming; Palushani, Evarist

2013-01-01

320 Gb/s Nyquist-OTDM is generated by rectangular filtering with a bandwidth of 320 GHz and received by polarization-insensitive time-domain optical Fourier transformation (TD-OFT) followed by passive filtering. After the time-to-frequency mapping in the TD-OFT, the Nyquist-OTDM is converted into...

Rudolf Diesel

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 4. Rudolf Diesel - The Rational Inventor of a Heat Engine. Tilottama Shrinivasa. Article-in-a-Box Volume 17 Issue 4 April 2012 pp 319-320. Fulltext. Click here to view fulltext PDF. Permanent link:

7 CFR 1210.320 - Establishment and membership.

Science.gov (United States)

2010-01-01

....320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan National Watermelon Promotion Board...

21 CFR 173.320 - Chemicals for controlling microorganisms in cane-sugar and beet-sugar mills.

Science.gov (United States)

2010-04-01

...-sugar and beet-sugar mills. 173.320 Section 173.320 Food and Drugs FOOD AND DRUG ADMINISTRATION... controlling microorganisms in cane-sugar and beet-sugar mills. Agents for controlling microorganisms in cane-sugar and beet-sugar mills may be safely used in accordance with the following conditions: (a) They are...

MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

DEFF Research Database (Denmark)

Vishnubalaji, Radhakrishnan; Hamam, Rimi; Yue, Shijun

2016-01-01

gene targets for the miR-320 family. Inverse correlation between the expression of miR-320 members with SOX4, FOXM1, and FOXQ1 was observed in primary CRC patients' specimens, suggesting that these genes are likely bona fide targets for the miR-320 family. Interestingly, interrogation of the expression...... for the miR-320/SOX4/FOXM1/FOXQ1 axes in promoting CRC development and progression and suggest targeting those networks as potential therapeutic strategy for CRC....

Degenerative joint disease on MRI and physical activity: a clinical study of the knee joint in 320 patients

International Nuclear Information System (INIS)

Bachmann, G.F.; Rauber, K.; Damian, M.S.; Rau, W.S.; Basad, E.

1999-01-01

We examined 320 patients with MRI and arthroscopy after an acute trauma to evaluate MRI in diagnosis of degenerative joint disease of the knee in relation to sports activity and clinical data. Lesions of cartilage and menisci on MRI were registered by two radiologists in consensus without knowledge of arthroscopy. Arthroscopy demonstrated grade-1 to grade-4 lesions of cartilage on 729 of 1920 joint surfaces of 320 knees, and MRI diagnosed 14 % of grade-1, 32 % of grade-2, 94 % of grade-3, and 100 % of grade-4 lesions. Arthroscopy explored 1280 meniscal areas and showed degenerations in 10 %, tears in 11.4 %, and complex lesions in 9.2 %. Magnetic resonance imaging was in agreement with arthroscopy in 81 % showing more degenerations but less tears of menisci than arthroscopy. Using a global system for grading the total damage of the knee joint into none, mild, moderate, or severe changes, agreement between arthroscopy and MRI was found in 82 %. Magnetic resonance imaging and arthroscopy showed coherently that degree of degenerative joint changes was significantly correlated to patient age or previous knee trauma. Patients over 40 years had moderate to severe changes on MRI in 45 % and patients under 30 years in only 22 %. Knee joints with a history of trauma without complete structural or functional reconstitution showed marked changes on MRI in 57 %, whereas stable joints without such alterations had degenerative changes in only 26 %. There was no correlation of degenerative disease to gender, weight, type, frequency, and intensity of sports activity. Therefore, MRI is an effective non-invasive imaging method for exact localization and quantification of chronic joint changes of cartilage and menisci that recommends MRI for monitoring in sports medicine. (orig.) (orig.)

76 FR 72350 - Airworthiness Directives; Airbus Airplanes

Science.gov (United States)

2011-11-23

...-1253; Directorate Identifier 2011-NM-079-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A319, A320, and A321... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...

29 CFR 778.319 - Paying for but not counting hours worked.

Science.gov (United States)

2010-07-01

... working time under the Act, coupled with a provision that these hours will not be counted as working time... more hours have been worked, the employee must be paid overtime compensation at not less than one and... 29 Labor 3 2010-07-01 2010-07-01 false Paying for but not counting hours worked. 778.319 Section...

Preliminary Engineering Report contaminated groundwater seeps 317/319/ENE area

International Nuclear Information System (INIS)

1996-01-01

When the Resource Conservation and Recovery Act Facility Investigation (RFI) in the 317/319/ENE Area of Argonne National Laboratory-East (ANL-E) was being completed, groundwater was discovered moving to the surface through a series of seeps. The seeps are located approximately 600 ft south of the ANL fence line in Waterfall Glen Forest Preserve. Samples of this water were collected and analyzed for selected parameters. Two of five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14-25 μg/L), carbon tetrachloride (56-340 μg/L), and tetrachloroethylene (3-6 μg/L). The other seeps did not contain detectable levels of volatile organic compounds (VOCs). The water issuing from these two contaminated seeps flows into a narrow ravine, where it is visible as a trickle of water flowing through sand and gravel deposits on the floor of the ravine. Approximately 100-ft downstream of the seep area, the contaminated water is no longer visible, having drained back into the soil in the bed of the ravine. Figure 1 shows the location of the 317/319/ENE Area in relation to the ANL-E site and the Waterfall Glen Forest Preserve

The soluble receptor for vitamin B12 uptake (sCD320) increases during pregnancy and occurs in higher concentration in urine than in serum

DEFF Research Database (Denmark)

Abuyaman, Omar; Andreasen, Birgitte H; Kronborg, Camilla

2013-01-01

BACKGROUND: Cellular uptake of vitamin B12 (B12) demands binding of the vitamin to transcobalamin (TC) and recognition of TC-B12 (holoTC) by the receptor CD320, a receptor expressed in high quantities on human placenta. We have identified a soluble form of CD320 (sCD320) in serum and here we...... gestational weeks 17-41. sCD320, holoTC, total TC and complex formation between holoTC and sCD320 were measured by in-house ELISA methods, while creatinine was measured on the automatic platform Cobas 6000. Size exclusion chromatography was performed on a Superdex 200 column. RESULTS: Median (range) of serum...... was around two fold higher than in serum. Urinary sCD320/creatinine ratio correlated with serum sCD320 and reached a peak median level of 53 (30-101) pmol/mmol creatinine (week 35). sCD320 present in serum and urine showed the same elution pattern upon size exclusion chromatography. CONCLUSION: We report...

47 CFR 80.319 - Radiotelegraph distress call and message transmission procedure.

Science.gov (United States)

2010-10-01

...) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Distress, Alarm, Urgency and Safety Procedures § 80.319 Radiotelegraph distress call and message...

Dose assessment of head CT examination by volume scanning with 320-area-detector

International Nuclear Information System (INIS)

Suzuki, Shoichi; Kobayashi, Masanao

2009-01-01

CT with the 320-area-detector (320-ADCT), first presented in 2007, still requires further basic studies, particularly in the field of dose assessment, as the CT has been widely spread in clinic due to its many advantages compared with the usual spiral CT. In this paper, the assessment in the title was thereby done in human phantom and a patient with suspicious acute cerebral infarction under different scanning modes (non-spiral, spiral and volume) for their comparison. Machines for 320-ADCT, and non-spiral and spiral CT were Toshiba Aquilion ONE, and Aquilion 64-MD, respectively. Scanning of the phantom and patient was individually conducted under similar conditions of tube voltage/ current, rotation time and length with the same field of view with defined nominal slice thicknesses. Alderson human body phantom in which 240 thermoluminescent dosimeters were indwelled, was used; doses were read by the thermoluminescence dosimeter (TLD) reader model 3000 (Kyokko Co.) after scanning; and effective doses were calculated with reference to ICRP publ. 102/103 equations for patient's head to be 4.2 (64-MDCT) and 6.6 (320-ADCT) mSv, which were respectively 6.4 and 5.4 mSv when estimated using the conversion coefficient and DLP (dose length product) in the texts. It was suggested that the exposure dose at the volume scanning by 320-ADCT can be reduced in the routine examination, and in the exact diagnosis, possibly increases. These doses can be reduced further by optimization of scanning conditions by additional basic investigations. (K.T.)

49 CFR 385.319 - What happens after completion of the safety audit?

Science.gov (United States)

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false What happens after completion of the safety audit... REGULATIONS SAFETY FITNESS PROCEDURES New Entrant Safety Assurance Program § 385.319 What happens after completion of the safety audit? (a) Upon completion of the safety audit, the auditor will review the findings...

Nonpoint Source Pollution Control Projects Grants (Section 319) - 2008 active projects

Data.gov (United States)

U.S. Environmental Protection Agency — The California Nonpoint Source (NPS) Program allocates about $4.5 million of CWA Section 319 funding from the U.S. Environmental Protection Agency annually to...

7 CFR 319.56-7 - Territorial applicability and exceptions.

Science.gov (United States)

2010-01-01

... chempedak), citrus, curacao apple, guava, Malay or mountain apple (Syzygium spp.), mango, and papaya, and... other containers made of coconut fronds are not approved for use as containers for fruits and vegetables... exempt from the permit requirements of § 319.56-3(b); and (ii) Mangoes grown in the British Virgin...

Influence of Fluidized Bed Quenching on the Mechanical Properties and Quality Index of T6 Tempered B319.2-Type Aluminum Alloys

Science.gov (United States)

Ragab, Kh. A.; Samuel, A. M.; Al-Ahmari, A. M. A.; Samuel, F. H.; Doty, H. W.

2013-11-01

The current study aimed to investigate the effect of fluidized sand bed (FB) quenching on the mechanical performance of B319.2 aluminum cast alloys. Traditional water and conventional hot air (CF) quenching media were used to establish a relevant comparison with FB quenching. Quality charts were generated using two models of quality indices to support the selection of material conditions on the basis of the proposed quality indices. The use of an FB for the direct quenching-aging treatment of B319.2 casting alloys yields greater UTS and YS values compared to conventional furnace quenched alloys. The strength values of T6 tempered B319 alloys are greater when quenched in water compared with those quenched in an FB or CF. For the same aging conditions (170°C/4h), the fluidized bed quenched-aged 319 alloys show nearly the same or better strength values than those quenched in water and then aged in a CF or an FB. Based on the quality charts developed for alloys subjected to different quenching media, higher quality index values are obtained by conventional furnace quenched-aged T6-tempered B319 alloys. The modification factor has the most significant effect on the quality results of the alloys investigated, for all heat treatment cycles, as compared to other metallurgical parameters. The results of alloys subjected to multi-temperature aging cycles reveal that the optimum strength properties of B319.2 alloys, however, is obtained by applying multi-temperature aging cycles such as, for example, 240 °C/2 h followed by 170 °C/8 h, rather than T6 aging treatments. The regression models indicate that the mean quality values of B319 alloys are highly quench sensitive due to the formation of a larger percent of clusters in Al-Si-Cu-Mg alloys. These clusters act as heterogeneous nucleation sites for precipitation and enhance the aging process.

50 CFR 660.320 - Open access fishery-crossover provisions.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Open access fishery-crossover provisions... West Coast Groundfish-Open Access Fisheries § 660.320 Open access fishery—crossover provisions. (a) Operating in both limited entry and open access fisheries. See provisions at § 660.60, subpart C. (b...

Tilottama Shrinivasa

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. Tilottama Shrinivasa. Articles written in Resonance – Journal of Science Education. Volume 17 Issue 4 April 2012 pp 319-320 Article-in-a-Box. Rudolf Diesel - The Rational Inventor of a Heat Engine · Tilottama Shrinivasa · More Details Fulltext PDF ...

32 CFR 644.318 - Compliance with State Coastal Zone Management Programs.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Compliance with State Coastal Zone Management... (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal § 644.318 Compliance with State Coastal Zone Management Programs. Subpart H will outline the provisions of the Coastal Zone Management Act of 1972, as...

9 CFR 320.3 - Record retention period.

Science.gov (United States)

2010-01-01

... 320.3 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND... the person required to keep such records under this part. (b) Records of canning as required in...

Laser shock wave consolidation of nanodiamond powders on aluminum 319

Energy Technology Data Exchange (ETDEWEB)

Molian, Pal [Laboratory for Lasers, MEMS, and Nanotechnology, Department of Mechanical Engineering, Iowa State University, Ames, IA 50011-2161 (United States)], E-mail: molian@iastate.edu; Molian, Raathai; Nair, Rajeev [Laboratory for Lasers, MEMS, and Nanotechnology, Department of Mechanical Engineering, Iowa State University, Ames, IA 50011-2161 (United States)

2009-01-01

A novel coating approach, based on laser shock wave generation, was employed to induce compressive pressures up to 5 GPa and compact nanodiamond (ND) powders (4-8 nm) on aluminum 319 substrate. Raman scattering indicated that the coating consisted of amorphous carbon and nanocrystalline graphite with peaks at 1360 cm{sup -1} and 1600 cm{sup -1} respectively. Scanning electron microscopy revealed a wavy, non-uniform coating with an average thickness of 40 {mu}m and absence of thermal effect on the surrounding material. The phase transition from nanodiamond to other phases of carbon is responsible for the increased coating thickness. Vicker's microhardness test showed hardness in excess of 1000 kg{sub f}/mm{sup 2} (10 GPa) while nanoindentation test indicated much lower hardness in the range of 20 MPa to 2 GPa. Optical surface profilometry traces displayed slightly uneven surfaces compared to the bare aluminum with an average surface roughness (R{sub a}) in the range of 1.5-4 {mu}m depending on the shock wave pressure and type of confining medium. Ball-on-disc tribometer tests showed that the coefficient of friction and wear rate were substantially lower than the smoother, bare aluminum sample. Laser shock wave process has thus aided in the generation of a strong, wear resistant, durable carbon composite coating on aluminum 319 substrate.

W-320 Project thermal modeling

Energy Technology Data Exchange (ETDEWEB)

Sathyanarayana, K., Fluor Daniel Hanford

1997-03-18

This report summarizes the results of thermal analysis performed to provide a technical basis in support of Project W-320 to retrieve by sluicing the sludge in Tank 241-C-106 and to transfer into Tank 241-AY-102. Prior theraml evaluations in support of Project W-320 safety analysis assumed the availability of 2000 to 3000 CFM, as provided by Tank Farm Operations, for tank floor cooling channels from the secondary ventilation system. As this flow availability has no technical basis, a detailed Tank 241-AY-102 secondary ventilation and floor coating channel flow model was developed and analysis was performed. The results of the analysis show that only about 150 cfm flow is in floor cooLing channels. Tank 241-AY-102 thermal evaluation was performed to determine the necessary cooling flow for floor cooling channels using W-030 primary ventilation system for different quantities of Tank 241-C-106 sludge transfer into Tank 241-AY-102. These sludge transfers meet different options for the project along with minimum required modification of the ventilation system. Also the results of analysis for the amount of sludge transfer using the current system is presented. The effect of sludge fluffing factor, heat generation rate and its distribution between supernatant and sludge in Tank 241-AY-102 on the amount of sludge transfer from Tank 241-C-106 were evaluated and the results are discussed. Also transient thermal analysis was performed to estimate the time to reach the steady state. For a 2 feet sludge transfer, about 3 months time will be requirad to reach steady state. Therefore, for the purpose of process control, a detailed transient thermal analysis using GOTH Computer Code will be required to determine transient response of the sludge in Tank 241-AY-102. Process control considerations are also discussed to eliminate the potential for a steam bump during retrieval and storage in Tanks 241-C-106 and 241-AY-102 respectively.

Microstructural features associated with the effect of temperature on the dimensional stability of an automotive Al-A319 alloy

Directory of Open Access Journals (Sweden)

Hugo F. Lopez

2016-05-01

Full Text Available In this work an automotive Al-A319 was given a solid solution heat treatment (T4 at 753 K (480 °C for 4.5 hours and an ageing treatment (T7 at 513 K (240 °C for various times up to 3.0 h. The alloy in the T4 condition was dilatometrically tested at various temperatures in order to measure its relative dimensional changes. It was found that the dimensional changes are due to both, alloy thermal expansion and nucleation and growth of second phases. In addition, in the T7 condition the alloy strength and ductility were determined as a function of ageing times. Ageing promoted alloy strength but at the expenses of a rather poor alloy ductility (down to 1%. Apparently, Cu rich intermetallic phases and regions provided a brittle path for fracturing. In particular, microstructural characterization using high resolution transmission electron microscopy indicated that not all the Cu in the matrix was dissolved during the T4 treatment. Hence, after ageing (T7 these Cu-rich regions seemed to coarsen into spherical particles.

Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320 row detector computed tomography

DEFF Research Database (Denmark)

Vavere, Andrea L; Simon, Gregory G; George, Richard T

2013-01-01

Multidetector coronary computed tomography angiography (CTA) is a promising modality for widespread clinical application because of its noninvasive nature and high diagnostic accuracy as found in previous studies using 64 to 320 simultaneous detector rows. It is, however, limited in its ability...... to detect myocardial ischemia. In this article, we describe the design of the CORE320 study ("Combined coronary atherosclerosis and myocardial perfusion evaluation using 320 detector row computed tomography"). This prospective, multicenter, multinational study is unique in that it is designed to assess...... the diagnostic performance of combined 320-row CTA and myocardial CT perfusion imaging (CTP) in comparison with the combination of invasive coronary angiography and single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI). The trial is being performed at 16 medical centers located in 8...

7 CFR 58.318 - Butter, frozen or plastic cream melting machines.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Butter, frozen or plastic cream melting machines. 58... Service 1 Equipment and Utensils § 58.318 Butter, frozen or plastic cream melting machines. Shavers, shredders or melting machines used for rapid melting of butter, frozen or plastic cream shall be of...

Project W-320, 241-C-106 sluicing: Piping calculations. Volume 4

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the FDNW calculations for Project W-320 readily retrievable. The objective of this calculation is to perform the structural analysis of the Pipe Supports designed for Slurry and Supernate transfer pipe lines in order to meet the requirements of applicable ASME codes. The pipe support design loads are obtained from the piping stress calculations W320-27-I-4 and W320-27-I-5. These loads are the total summation of the gravity, pressure, thermal and seismic loads. Since standard typical designs are used for each type of pipe support such as Y-Stop, Guide and Anchors, each type of support is evaluated for the maximum loads to which this type of supports are subjected. These loads are obtained from the AutoPipe analysis and used to check the structural adequacy of these supports

Project W-320, 241-C-106 sluicing: Piping calculations. Volume 4

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-24

This supporting document has been prepared to make the FDNW calculations for Project W-320 readily retrievable. The objective of this calculation is to perform the structural analysis of the Pipe Supports designed for Slurry and Supernate transfer pipe lines in order to meet the requirements of applicable ASME codes. The pipe support design loads are obtained from the piping stress calculations W320-27-I-4 and W320-27-I-5. These loads are the total summation of the gravity, pressure, thermal and seismic loads. Since standard typical designs are used for each type of pipe support such as Y-Stop, Guide and Anchors, each type of support is evaluated for the maximum loads to which this type of supports are subjected. These loads are obtained from the AutoPipe analysis and used to check the structural adequacy of these supports.

30 CFR 75.320 - Air quality detectors and measurement devices.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Air quality detectors and measurement devices... COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.320 Air quality detectors and measurement devices. (a) Tests for methane shall be made by a qualified person with...

Project W-320, 241-C-106 sluicing: Piping calculations. Volume 8

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the FDNW calculations for Project W-320 readily retrievable. The objective of this calculation is to perform the hydraulic analysis on the slurry line and the supernate line for W-320. This calculation will use the As-Built conditions of the slurry line and the supernate line. Booster Pump Curves vs System Curves shall be generated for the supernate system and the slurry system

A 320 Year Ice-Core Record of Atmospheric Hg Pollution in the Altai, Central Asia.

Science.gov (United States)

Eyrikh, Stella; Eichler, Anja; Tobler, Leonhard; Malygina, Natalia; Papina, Tatyana; Schwikowski, Margit

2017-10-17

Anthropogenic emissions of the toxic heavy metal mercury (Hg) have substantially increased atmospheric Hg levels during the 20th century compared to preindustrial times. However, on a regional scale, atmospheric Hg concentration or deposition trends vary to such an extent during the industrial period that the consequences of recent Asian emissions on atmospheric Hg levels are still unclear. Here we present a 320 year Hg deposition history for Central Asia, based on a continuous high-resolution ice-core Hg record from the Belukha glacier in the Siberian Altai, covering the time period 1680-2001. Hg concentrations and deposition fluxes start rising above background levels at the beginning of the 19th century due to emissions from gold/silver mining and Hg production. A steep increase occurs after the 1940s culminating during the 1970s, at the same time as the maximum Hg use in consumer products in Europe and North America. After a distinct decrease in the 1980s, Hg levels in the 1990s and beginning of the 2000s return to their maximum values, which we attribute to increased Hg emissions from Asia. Thus, rising Hg emissions from coal combustion and artisanal and small-scale gold mining (ASGM) in Asian countries determine recent atmospheric Hg levels in Central Asia, counteracting emission reductions due to control measures in Europe and North America.

32 CFR 320.4 - Procedures for requesting information.

Science.gov (United States)

2010-07-01

... (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.4 Procedures for... Directive 7650.1 1 “GAO Access to Records”. 1 Copies may be obtained via Internet at http://www.dtic.mil/whs...

Experimental Demonstration of 32 Gbaud 4-PAM for Data Center Interconnections of up to 320 km

DEFF Research Database (Denmark)

Madsen, Peter; Suhr, Lau Frejstrup; Clausen, Anders

2017-01-01

This paper presents experimental results demonstrating a 64 Gbps 4-PAM transmission over a 320 km SSMF span employing standard 80 km fiber spans for metro links. The receiver consists of a LPF and a DFE utilizing the DD-LMS algorithm.......This paper presents experimental results demonstrating a 64 Gbps 4-PAM transmission over a 320 km SSMF span employing standard 80 km fiber spans for metro links. The receiver consists of a LPF and a DFE utilizing the DD-LMS algorithm....

Deployment of phytoremediation at the 317/319 area at Argonne National Laboratory - East

International Nuclear Information System (INIS)

Negri, M. C.; Hinchman, R. R.; Quinn, J.; Wozniak, J.

2000-01-01

The 317 and 319 Areas are located on the extreme southern end of the ANL-E site, immediately adjacent to the DuPage County Waterfall Glen Forest Preserve. The 317 Area is an active hazardous and radioactive waste processing and storage area. In the late 1950s, liquid waste was placed in the unit known as the French Drain. Since that time, this waste has migrated into underlying soil and groundwater. The principal environmental concern in the 317 Area is the presence of several VOCs in the soil and groundwater and low levels of tritium in the groundwater beneath and down gradient of the site. The 319 Area Landfill and French Drain are located immediately adjacent to the 317 Area. The principal environmental concern in the 319 Area is the presence of radioactive materials in the waste mound, in the leachate in the mound, and in the shallow groundwater immediately down gradient of the landfill. Several interim actions have already been implemented in this area, to reduce the VOC and tritium releases from these areas, as the result of the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) conducted from December 1994 through September 1996

23 CFR 450.320 - Congestion management process in transportation management areas.

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Congestion management process in transportation... Programming § 450.320 Congestion management process in transportation management areas. (a) The transportation planning process in a TMA shall address congestion management through a process that provides for safe and...

9 CFR 318.12 - Manufacture of dog food or similar uninspected article at official establishments.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Manufacture of dog food or similar... ESTABLISHMENTS; REINSPECTION AND PREPARATION OF PRODUCTS General § 318.12 Manufacture of dog food or similar uninspected article at official establishments. (a) When dog food, or similar uninspected article is...

41 CFR 102-75.320 - Does appraisal information need to be kept confidential?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Does appraisal information need to be kept confidential? 102-75.320 Section 102-75.320 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 75-REAL PROPERTY DISPOSAL Surplus Real...

The hyperluminous infrared quasar 3C 318 and its implications for interpreting sub-mm detections of high-redshift radio galaxies

OpenAIRE

Willott, Chris J.; Rawlings, Steve; Jarvis, Matt J.

1999-01-01

We present near-infrared spectroscopy and imaging of the compact steep- spectrum radio source 3C 318 which shows it to be a quasar at redshift z=1.574 (the z=0.752 value previously reported is incorrect). 3C 318 is an IRAS, ISO and SCUBA source so its new redshift makes it the most intrinsically luminous far-infrared (FIR) source in the 3C catalogue (there is no evidence of strong gravitational lensing effects). Its bolometric luminosity greatly exceeds the 10^13 solar luminosity level above ...

7 CFR 319.41-1 - Plant products permitted entry. 1

Science.gov (United States)

2010-01-01

... risk is involved in their entry. (3) Corn silk. (b) Upon compliance with the regulations in this... INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Indian Corn or Maize, Broomcorn, and... countries. (§ 319.15.) (b) Except as provided for in paragraph (c) for corn seed from New Zealand, seed and...

20 CFR 670.320 - What are the requirements for award of contracts and payments to Federal agencies?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What are the requirements for award of contracts and payments to Federal agencies? 670.320 Section 670.320 Employees' Benefits EMPLOYMENT AND... Funding and Selection of Service Providers § 670.320 What are the requirements for award of contracts and...

Diagnostic performance of 320-detector CT coronary angiography in patients with atrial fibrillation: preliminary results

Energy Technology Data Exchange (ETDEWEB)

Xu, Lei; Yang, Lin; Fan, Zhanming; Yu, Wei; Lv, Biao; Zhang, Zhaoqi [Capital Medical University, Department of Radiology, Beijing Anzhen Hospital, Beijing (China)

2011-05-15

To evaluate the feasibility, diagnostic accuracy, and radiation dose of CT coronary angiography (CTCA) in patients with atrial fibrillation (AF) using 320-detector CT. Thirty-seven patients with persistent AF and suspected coronary artery disease (CAD) were enrolled. All patients underwent both 320-detector CTCA and conventional coronary angiography (CCA). CT image quality and the presence of significant ({>=}50%) stenosis were evaluated by two radiologists blinded to the results of CCA. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated using CCA as the reference standard. Differences in detection of coronary artery stenosis between 320-detector CTCA and CCA were evaluated with McNemar's test. Patient radiation dose was calculated by multiplying dose length product by conversion coefficient of 0.017. In total 474 evaluated coronary segments, 459 (96.8%) segments were diagnostically evaluable. On per-segment analysis, sensitivity, specificity, PPV and NPV were 90.0% (18 of 20), 99.3% (436 of 439), 85.7% (18 of 21) and 99.5% (436 of 438). No significant difference was found between 320-detector CTCA and CCA on the detection of significant stenosis (P = 1.000). Effective doses of 320-detector CTCA was 13.0 {+-} 4.7 mSv. 320-detector CTCA is feasible and accurate in excluding CAD in patients with AF. (orig.)

7 CFR 319.56-26 - Melon and watermelon from certain countries in South America.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Melon and watermelon from certain countries in South... and Vegetables § 319.56-26 Melon and watermelon from certain countries in South America. (a) Cantaloupe and watermelon from Ecuador. Cantaloupe (Cucumis melo) and watermelon (fruit) (Citrullus lanatus...

39 CFR 320.9 - Revocation or amendment of suspensions.

Science.gov (United States)

2010-07-01

... SUSPENSION OF THE PRIVATE EXPRESS STATUTES § 320.9 Revocation or amendment of suspensions. These suspensions... of operations (in dollar or volume terms, whichever is larger) lower than that antedating the...

78 FR 69318 - Airworthiness Directives; Rockwell Collins, Inc. Transponders

Science.gov (United States)

2013-11-19

... We invite you to send any written relevant data, views, or arguments about this proposal. Send your... with the transponders that could lead to increased pilot and air traffic controller workload as well as..., certificated in any category: (i) Airbus Models A319, A320, A330, A340; and (ii) Boeing Models B777, B747, MD...

Optical band gap of ZnO thin films deposited by electron beam evaporation

International Nuclear Information System (INIS)

Nadeem, M. Y.; Ali, S. L.; Wasiq, M. F.; Rana, A. M.

2006-01-01

Optical band gap of ZnO thin films deposited by electron beam evaporation at evaporation rates ranging 5 As/sup -1/ to 15 As /sup -1/ and thickness ranging 1000A to 3000A is presented. Deposited films were annealed at 573K for one and half hour. The variations in the optical band gap were observed and showed decreasing behavior from 3.15 eV, 3.05 eV, from 3.18 eV to 3.10 eV and from 3.19 eV to 3.18 eV for films with respective thickness 1000A, 2000 A, 3000 A on increasing the evaporation rate from 5 As/sup-1/ to As/sup -1/ by keeping thickness constant. (author)

A percepção dos profissionais de Contabilidade no âmbito da Prefeitura do Município De São Paulo, de Necessidades de mudanças na Lei 4.320/64: sintomas da necessidade de mudança

Directory of Open Access Journals (Sweden)

Marília Cássia Teixeira

2013-07-01

Full Text Available Neste trabalho de título a percepção dos profissionais de contabilidade no âmbito da Prefeitura do Município de São Paulo, das mudanças da Lei 4.320/64 e o impacto da Lei 101/00 , buscou-se alcançar o objetivo de captar a percepção dos profissionais de contabilidade no âmbito da Prefeitura do Município de São Paulo, das mudanças da Lei 4.320/64 e o impacto da Lei 101/00 e considerado o atual estado de harmonização das práticas contábeis do setor público. Neste contexto investigou-se a seguinte questão de pesquisa:  Existe a necessidade de mudança na Lei 4320/64, na percepção dos técnicos, gestores e auditores do Tribunal de Contas do Município de São Paulo?  A pesquisa foi realizada através da aplicação de um questionário a vinte e um profissionais de Contabilidade, do município com funções de gestão, de operação e auditores do tribunal de contas. Pelas respostas obtidas verificou-se que, na percepção destes indivíduos, a Lei 4.320/64 carece de atualização. Outros aspectos como a complexidade da lei em relação ao tamanho de muitos municípios foram levantados, bem como a necessidade de uma interpretação uniforme da Lei. Os conflitos entre a Lei 4.320/64 e a Lei Complementar 101/00 são resolvidos, seguindo o que estabelece a LC 101/00, por ser mais recente. Foi colocado ainda que, na visão destes profissionais, a harmonização das práticas contábeis é inevitável também no setor público, posto o atual grau de globalização que vivemos.

21 CFR 111.320 - What requirements apply to laboratory methods for testing and examination?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to laboratory methods for testing and examination? 111.320 Section 111.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING...

Left atrial passive emptying function is preserved in patients with permanent atrial fibrillation--a 320-slice multidetector computed tomography study

DEFF Research Database (Denmark)

Agner, Bue Fridolin Ross; Kühl, Jørgen Tobias; Kofoed, Klaus Fuglsang

2014-01-01

OBJECTIVE: Left atrial (LA) mechanical function is thought to be virtually inexistent in patients with permanent atrial fibrillation (AF). Due to recent advances in multidetector computed tomography (MDCT) technology, it is now possible to acquire images of the entire heart in a single heartbeat....... The objective of this study was to compare individual components of LA function assessed by MDCT in patients with permanent AF and patients in sinus rhythm (SR). METHODS: 320-slice MDCT was performed in 30 patients with permanent AF. Measurements of LA volumes during the cardiac cycle were compared to 30......; 71 vs. 30 ml/m(2), p permanent AF have significantly increased LA volumes throughout the cardiac...

40 CFR 1045.320 - What happens if one of my production-line engines fails to meet emission standards?

Science.gov (United States)

2010-07-01

...-line engines fails to meet emission standards? 1045.320 Section 1045.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Testing Production-line Engines § 1045.320 What happens if one of my...

40 CFR 1048.320 - What happens if one of my production-line engines fails to meet emission standards?

Science.gov (United States)

2010-07-01

...-line engines fails to meet emission standards? 1048.320 Section 1048.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing Production-line Engines § 1048.320 What happens if one of my production...

Chronic exposure of Sk-1 hairless mice to narrow-band ultraviolet A (320-355 nm)

International Nuclear Information System (INIS)

Menter, J.M.; Sayre, R.M.; Etemadi, A.A.; Agin, P.P.; Wills, I.

1996-01-01

Several recent investigations collectively suggest that the role of ultraviolet A (UVA) in chronic actinic skin damage may be greater than originally thought. In the present work, the output of a xenon-arc solar-simulator passed through a Bausch and Lomb monochromator in conjunction with a 2-mm Schott WG-320 filter produced narrow-band UVA centered at 338 nm, half-band width 24 nm, I 0 =3.4±0.3 mW/cm 2 . We chronically irradiated 10 SK-1 albino hairless mice 5 times per week for 18 weeks, starting with 1.25 J/cm 2 , for 33 irradiation days, sequentially followed by 1.50 J/cm 2 (34 days), 1.8 J/cm 2 (10 days), 2.0 J/cm 2 (22 days) to afford a total UVA dose of 154.3 J/cm 2 over 99 irradiation days. Erythema was noted clinically by day 6, which persisted throughout the irradiation. During the irradiation period, some scaling, consistent with mild epidermal hyperplasia was noted during irradiation days 37-56. This response later regressed despite continued chronic irradiation. Hematoxylin and eosin examination immediately after the final irradiation revealed a mild inflammatory response, with some dermal restructuring. At the end of the experiment, no significant signs of epidermal hyperplasia or (pre)malignant lesions were seen, although some stratum corneum thickening was noted. Marked dermal collagen damage and moderate elastosis was also evident. We believe that the observed differences in results reported in previous studies are in large part due to differences in light sources and irradiation protocols. (au)

7 CFR 319.56-42 - Peppers from the Republic of Korea.

Science.gov (United States)

2010-01-01

... INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Fruits and Vegetables § 319.56-42... tarpaulin while in transit from the production site to the packinghouse and while awaiting packing. The... tarpaulin, for transit to the continental United States. These safeguards must remain intact until the...

7 CFR 319.59-3 - Articles prohibited importation pending risk evaluation.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Articles prohibited importation pending risk... Diseases § 319.59-3 Articles prohibited importation pending risk evaluation. The articles listed in...(b), pending the completion of an evaluation by APHIS of the potential pest risks associated with the...

Bacteria classification using Cyranose 320 electronic nose

Directory of Open Access Journals (Sweden)

Gardner Julian W

2002-10-01

Full Text Available Abstract Background An electronic nose (e-nose, the Cyrano Sciences' Cyranose 320, comprising an array of thirty-two polymer carbon black composite sensors has been used to identify six species of bacteria responsible for eye infections when present at a range of concentrations in saline solutions. Readings were taken from the headspace of the samples by manually introducing the portable e-nose system into a sterile glass containing a fixed volume of bacteria in suspension. Gathered data were a very complex mixture of different chemical compounds. Method Linear Principal Component Analysis (PCA method was able to classify four classes of bacteria out of six classes though in reality other two classes were not better evident from PCA analysis and we got 74% classification accuracy from PCA. An innovative data clustering approach was investigated for these bacteria data by combining the 3-dimensional scatter plot, Fuzzy C Means (FCM and Self Organizing Map (SOM network. Using these three data clustering algorithms simultaneously better 'classification' of six eye bacteria classes were represented. Then three supervised classifiers, namely Multi Layer Perceptron (MLP, Probabilistic Neural network (PNN and Radial basis function network (RBF, were used to classify the six bacteria classes. Results A [6 × 1] SOM network gave 96% accuracy for bacteria classification which was best accuracy. A comparative evaluation of the classifiers was conducted for this application. The best results suggest that we are able to predict six classes of bacteria with up to 98% accuracy with the application of the RBF network. Conclusion This type of bacteria data analysis and feature extraction is very difficult. But we can conclude that this combined use of three nonlinear methods can solve the feature extraction problem with very complex data and enhance the performance of Cyranose 320.

Simulation of the concomitant process of nucleation-growth-coarsening of Al2Cu particles in a 319 foundry aluminum alloy

International Nuclear Information System (INIS)

Martinez, R; Larouche, D; Cailletaud, G; Guillot, I; Massinon, D

2015-01-01

The precipitation of Al 2 Cu particles in a 319 T7 aluminum alloy has been modeled. A theoretical approach enables the concomitant computation of nucleation, growth and coarsening. The framework is based on an implicit scheme using the finite differences. The equation of continuity is discretized in time and space in order to obtain a matricial form. The inversion of a tridiagonal matrix gives way to determining the evolution of the size distribution of Al 2 Cu particles at t  +Δt. The fluxes of in-between the boundaries are computed in order to respect the conservation of the mass of the system, as well as the fluxes at the boundaries. The essential results of the model are compared to TEM measurements. Simulations provide quantitative features on the impact of the cooling rate on the size distribution of particles. They also provide results in agreement with the TEM measurements. This kind of multiscale approach allows new perspectives to be examined in the process of designing highly loaded components such as cylinder heads. It enables a more precise prediction of the microstructure and its evolution as a function of continuous cooling rates. (paper)

The Hyperluminous Infrared Quasar 3C 318 and Its Implications for Interpreting Sub-MM Detections of High-Redshift Radio Galaxies

Science.gov (United States)

Willott, Chris J.; Rawlings, Steve; Jarvis, Matt J.

1999-01-01

We present near-infrared spectroscopy and imaging of the compact steep-spectrum radio source 3C 318 which shows it to be a quasar at redshift z = 1.574 (the z = 0.752 value previously reported is incorrect). 3C 318 is an IRAS, ISO and SCUBA source so its new redshift makes it the most intrinsically luminous far-infrared (FIR) source in the 3C catalogue (there is no evidence of strong gravitational lensing effects). Its bolometric luminosity greatly exceeds the 10(exp 13) solar luminosity level above which an object is said to be hyperluminous. Its spectral energy distribution (SED) requires that the quasar heats the dust responsible for the FIR flux, as is believed to be the case in other hyperluminous galaxies, and contributes (at the greater than 10% level) to the heating of the CIA dust responsible for the sub-mm emission. We cannot determine whether a starburst makes an important contribution to the heating of the coolest dust, so evidence for a high star-formation rate is circumstantial being based on the high dust, and hence gas, C-1 mass required by its sub-mm detection. We show that the current sub-mm and FIR data available for the highest-redshift radio galaxies are consistent with SEDs similar to that of 3C 318. This indicates that at least some of this population may be detected in the sub-mm because of dust heated by the quasar nucleus, and that interpreting sub-mm detection as evidence for very high (approx. less than 1000 solar mass/yr) star-formation rates may not always be valid. We show that the 3C318 quasar is slightly reddened (A(sub v) approx. = 0.5), the most likely cause of which is SMC-type dust in the host galaxy. If very distant radio galaxies are reddened in a similar way then we show that only slightly greater amounts of dust could obscure the quasars in these sources. We speculate that the low fraction of quasars amongst the very high redshift (z approx. greater than 3) objects in low-frequency radio-selected samples is the result of

The soluble transcobalamin receptor (sCD320) is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta

DEFF Research Database (Denmark)

Abuyaman, Omar; Nexo, Ebba

2015-01-01

BACKGROUND: Cellular uptake of vitamin B12 (B12) demands binding of the vitamin to transcobalamin (TC) and recognition of TC-B12 (holoTC) by the receptor CD320. Recently, we identified a soluble form of CD320 (sCD320) in human plasma. Here we present data on the occurrence of this soluble receptor...... phospho-tau (181P) (p-tau), total tau (t-tau) and amyloid-beta 1-42 (Aβ) (n = 177) employing commercial ELISA kits (Innogenetics Company). Size exclusion chromatography was performed on a Superdex 200 column. RESULTS: The median sCD320 concentration in CSF (14 pmol/L) is around five times lower than...

A statistical study of sporadic sodium layer observed by Sodium lidar at Hefei (31.8° N, 117.3° E

Directory of Open Access Journals (Sweden)

X.-K. Dou

2009-06-01

Full Text Available Sodium lidar observations of sporadic sodium layers (SSLs during the past 3 years at a mid-latitude location (Hefei, China, 31.8° N, 117.3° E are reported in this paper. From 64 SSL events detected in about 900 h of observation, an SSL occurrence rate of 1 event every 14 h at our location was obtained. This result, combined with previous studies, reveals that the SSL occurrence can be relatively frequent at some mid-latitude locations. Statistical analysis of main parameters for the 64 SSL events was performed. By examining the corresponding data from an ionosonde, a considerable correlation was found with a Pearson coefficient of 0.66 between seasonal variations of SSL and those of sporadic E (Es during nighttime, which was in line with the research by Nagasawa and Abo (1995. From comparison between observations from the University of Science and Technology of China (USTC lidar and from Wuhan Institute of Physics and Mathematics (WIPM lidar (Wuhan, China, 31° N, 114° E, the minimum horizontal range for some events was estimated to be over 500 km.

Comparative study WWER-440/230 reactors and the Juragua-based WWER-440/318 project

International Nuclear Information System (INIS)

1994-01-01

The work consists in a comparative analysis between WWER-440/230 and WWER-440/318 type reactors on the basis of the major findings and recommendations given in the extra budgetary Programme of the International Atomic Energy Agency on the safety of these reactors and summarized in the document 'The safety of WWER-440 model 230 nuclear power plant'. The fundamental emphasis was done in the design concept of these reactors

48 CFR 319.705 - Responsibilities of the Contracting Officer under the subcontracting assistance program.

Science.gov (United States)

2010-10-01

... Regulations System HEALTH AND HUMAN SERVICES SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Subcontracting With Small Business, Small Disadvantaged Business, and Women-Owned Small Business Concerns 319.705...

1,2,4-Triazole-based N-heterocyclic carbene complexes of gold(I): synthesis, characterization and biological activity

Czech Academy of Sciences Publication Activity Database

Turek, J.; Růžičková, Z.; Tloušťová, Eva; Mertlíková-Kaiserová, Helena; Günterová, Jana; Rulíšek, Lubomír; Růžička, A.

2016-01-01

Roč. 30, č. 5 (2016), s. 318-322 ISSN 0268-2605 R&D Projects: GA ČR(CZ) GA14-31419S; GA MŠk LO1302 Institutional support: RVO:61388963 Keywords : gold(I) complexes * N-heterocyclic carbenes * cytotoxicity * apoptosis Subject RIV: CC - Organic Chemistry Impact factor: 2.319, year: 2016

21 CFR 320.28 - Correlation of bioavailability with an acute pharmacological effect or clinical evidence.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Correlation of bioavailability with an acute pharmacological effect or clinical evidence. 320.28 Section 320.28 Food and Drugs FOOD AND DRUG ADMINISTRATION... Correlation of bioavailability with an acute pharmacological effect or clinical evidence. Correlation of in...

Bicyclo[3.2.0]heptane as a Core Structure for Conformational Locking of 1,3-Bis-Pharmacophores, Exemplified by GABA

DEFF Research Database (Denmark)

Vorberg, Raffael; Trapp, Nils; Carreira, Erick M

2017-01-01

The synthesis and X-ray crystal structures of syn and anti 4-N-Boc-aminobicyclo[3.2.0]heptane-1-carboxylic acids are described. The placement of the N-Boc-amino groups in the two stereoisomers in either pseudo-equatorial or pseudo-axial positions renders the molecules conformationally locked......, with N-Boc-protected γ-aminobutyric acid (GABA) embedded within the bicyclic core. Despite the different conformations of the urethane and distinct crystal packing, the bicyclic core units of the two stereoisomers adopt virtually identical structures. They correspond to in silico models of the parent...

24 CFR 888.320 - One-time Contract Rent determination.

Science.gov (United States)

2010-04-01

... PROGRAM, SECTION 202 SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES PROGRAM) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM-FAIR MARKET RENTS AND... Elderly or Handicapped, and Special Allocations Projects § 888.320 One-time Contract Rent determination...

Determination of correction and conversion factor of exposure rate generated Gamma spectrometer GR-320 to Victoreen data

International Nuclear Information System (INIS)

Supardjo-AS; Mappa, Djody-Rachim; Nasrun-Syamsul; Syamsul-Hadi

2000-01-01

Exposure rate data of Muria Peninsula were generated from Victoreen-491 measurement and calculation of radioelement content in soil which were measured by Exploranium GR-320, using IAEA formula. However those data are not be comparable so the exposure rate calculated from Gamma Spectrometer data necessarily to be corrected. The correction factor was determinate by measuring the exposure rate of at the NMDC's back yard selected location using Victoreen-491 and Gamma Spectrometer Exploranium GR-320 . Correction factor was created by comparing mean exposure rate data that calculated from 30 data measured by Gamma Spectrometer instrument and to those Victoreen's exposure rate. Conversion factor was gained from comparing of total count data of Gamma Spectrometer Exploranium GR-320 to Victoreen's exposure rate data. The correction factor of Exploranium GR-320's exposure rate is 0.34 μR/hours, and the conversion factor of total count is 0.0092 μR/hours per c/m. Deviation Victoreen 491 = 4.7 % and Gamma Spectrometer Exploranium GR-320 8.6 %

9 CFR 318.17 - Requirements for the production of cooked beef, roast beef, and cooked corned beef products.

Science.gov (United States)

2010-01-01

... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY... OFFICIAL ESTABLISHMENTS; REINSPECTION AND PREPARATION OF PRODUCTS General § 318.17 Requirements for the... must include a cooking step. Controlled intermediate step(s) applied to raw product may form part of...

25 CFR 20.318 - What case management responsibilities does the social services worker have?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What case management responsibilities does the social... HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Direct Assistance Employment Requirements § 20.318 What case management responsibilities does the social services worker have? In working...

40 CFR 1051.320 - What happens if one of my production-line vehicles or engines fails to meet emission standards?

Science.gov (United States)

2010-07-01

...-line vehicles or engines fails to meet emission standards? 1051.320 Section 1051.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing Production-Line Vehicles and Engines § 1051.320 What happens if one...

Effect of grain refinement on the microstructure and tensile properties of thin 319 Al castings

International Nuclear Information System (INIS)

Shabani, M.J.; Emamy, M.; Nemati, N.

2011-01-01

The structural examinations and tensile properties of thin-section Al castings (319 Al alloy) have been investigated by applying a pattern with different cross sections (2-12 mm). Al-5Ti-1B and Al-5Zr grain refiners were added to the molten Al alloy to produce different levels of Ti (0.01%, 0.05%, 0.1% and 0.15%) and Zr (0.05%, 0.1%, 0.2%, 0.3%, 0.4% and 0.5%) in the castings. From macrostructural studies, it was found that Al-5Zr is less effective in grain refining of 319 alloy in comparison with Al-5Ti-1B master alloy. The optimum levels of grain refiners were selected for determination of tensile properties. T6 heat treatment was applied for selected specimens before tensile testing. Further structural results also showed that thinner sections are less affected by grain refiners. This observation was found to be in a good agreement with tensile test results, where tensile properties of the base and grain refined alloys did not show considerable differences in thinner sections (<6 mm).

Isolation of a novel UVB-tolerant rice mutant obtained by exposure to carbon-ion beams.

Science.gov (United States)

Takano, Nao; Takahashi, Yuko; Yamamoto, Mitsuru; Teranishi, Mika; Yamaguchi, Hiroko; Sakamoto, Ayako N; Hase, Yoshihiro; Fujisawa, Hiroko; Wu, Jianzhong; Matsumoto, Takashi; Toki, Seiichi; Hidema, Jun

2013-07-01

UVB radiation suppresses photosynthesis and protein biosynthesis in plants, which in turn decreases growth and productivity. Here, an ultraviolet-B (UVB)-tolerant rice mutant, utr319 (UV Tolerant Rice 319), was isolated from a mutagenized population derived from 2500 M1 seeds (of the UVB-resistant cultivar 'Sasanishiki') that were exposed to carbon ions. The utr319 mutant was more tolerant to UVB than the wild type. Neither the levels of UVB-induced cyclobutane pyrimidine dimers (CPDs) or (6-4) pyrimidine-pyrimidone photodimers [(6-4) photoproducts], nor the repair of CPDs or (6-4) photoproducts, was altered in the utr319 mutant. Thus, the utr319 mutant may be impaired in the production of a previously unidentified factor that confers UVB tolerance. To identify the mutated region in the utr319 mutant, microarray-based comparative genomic hybridization analysis was performed. Two adjacent genes on chromosome 7, Os07g0264900 and Os07g0265100, were predicted to represent the mutant allele. Sequence analysis of the chromosome region in utr319 revealed a deletion of 45 419 bp. RNAi analysis indicated that Os07g0265100 is most likely the mutated gene. Database analysis indicated that the Os07g0265100 gene, UTR319, encodes a putative protein with unknown characteristics or function. In addition, the homologs of UTR319 are conserved only among land plants. Therefore, utr319 is a novel UVB-tolerant rice mutant and UTR319 may be crucial for the determination of UVB sensitivity in rice, although the function of UTR319 has not yet been determined.

Isolation of a novel UVB-tolerant rice mutant obtained by exposure to carbon-ion beams

International Nuclear Information System (INIS)

Takano, Nao; Takahashi, Yuko; Yamamoto, Mitsuru; Teranishi, Mika; Yamaguchi, Hiroko; Sakamoto, Ayako N.; Hase, Yoshihiro; Fujisawa, Hiroko; Wu, Jianzhong; Matsumoto, Takashi; Toki, Seiichi; Hidema, Jun

2013-01-01

UVB radiation suppresses photosynthesis and protein biosynthesis in plants, which in turn decreases growth and productivity. Here, an ultraviolet-B (UVB)-tolerant rice mutant, utr319 (UVTolerantRice319), was isolated from a mutagenized population derived from 2500 M 1 seeds (of the UVB-resistant cultivar ‘Sasanishiki’) that were exposed to carbon ions. The utr319 mutant was more tolerant to UVB than the wild type. Neither the levels of UVB-induced cyclobutane pyrimidine dimers (CPDs) or (6-4) pyrimidine-pyrimidone photodimers [(6-4) photoproducts], nor the repair of CPDs or (6-4) photoproducts, was altered in the utr319 mutant. Thus, the utr319 mutant may be impaired in the production of a previously unidentified factor that confers UVB tolerance. To identify the mutated region in the utr319 mutant, microarray-based comparative genomic hybridization analysis was performed. Two adjacent genes on chromosome 7, Os07g0264900 and Os07g0265100, were predicted to represent the mutant allele. Sequence analysis of the chromosome region in utr319 revealed a deletion of 45 419 bp. RNAi analysis indicated that Os07g0265100 is most likely the mutated gene. Database analysis indicated that the Os07g0265100 gene, UTR319, encodes a putative protein with unknown characteristics or function. In addition, the homologs of UTR319 are conserved only among land plants. Therefore, utr319 is a novel UVB-tolerant rice mutant and UTR319 may be crucial for the determination of UVB sensitivity in rice, although the function of UTR319 has not yet been determined

7 CFR 319.56-11 - Importation of dried, cured, or processed fruits, vegetables, nuts, and legumes.

Science.gov (United States)

2010-01-01

... QUARANTINE NOTICES Fruits and Vegetables § 319.56-11 Importation of dried, cured, or processed fruits, vegetables, nuts, and legumes. (a) Dried, cured, or processed fruits and vegetables (except frozen fruits and... 7 Agriculture 5 2010-01-01 2010-01-01 false Importation of dried, cured, or processed fruits...

Coronary computed tomography angiography with 320-row detector and using the AIDR-3D: initial experience; Angiotomografia computadorizada de coronarias com tomografo com 320 fileiras de detectores e utilizando o AIDR-3D: experiencia inicial

Energy Technology Data Exchange (ETDEWEB)

Sasdelli Neto, Roberto; Nomura, Cesar Higa; Macedo, Ana Carolina Sandoval; Bianco, Danilo Perussi; Kay, Fernando Uliana; Szarf, Gilberto; Teles, Gustavo Borges da Silva; Shoji, Hamilton; Santana Netto, Pedro Vieira; Passos, Rodrigo Bastos Duarte; Chate, Rodrigo Caruso; Ishikawa, Walther Yoshiharu; Lima, Joao Paulo Bacellar Costa; Rocha, Marcelo Assis; Marcos, Vinicius Neves; Funari, Marcelo Buarque de Gusmao, E-mail: roberto.neto@einstein.br [Hospital Israelita Albert Einstein, Sao Paulo, SP (Brazil); Failla, Bruna Bonaventura [Universidade Metodista de Sao Paulo, Sao Bernardo do Campo, SP (Brazil)

2013-07-01

Coronary computed tomography angiography (coronary CTA) is a powerful non-invasive imaging method to evaluate coronary artery disease. Nowadays, coronary CTA estimated effective radiation dose can be dramatically reduced using state-of-the-art scanners, such as 320-row detector CT (320-CT), without changing coronary CTA diagnostic accuracy. To optimize and further reduce the radiation dose, new iterative reconstruction algorithms were released recently by several CT manufacturers, and now they are used routinely in coronary CTA. This paper presents our first experience using coronary CTA with 320-CT and the Adaptive Iterative Dose Reduction 3D (AIDR-3D). In addition, we describe the current indications for coronary CTA in our practice as well as the acquisition standard protocols and protocols related to CT application for radiation dose reduction. In conclusion, coronary CTA radiation dose can be dramatically reduced following the 'as low as reasonable achievable' principle by combination of exam indication and well-documented technics for radiation dose reduction, such as beta blockers, low-kV, and also the newest iterative dose reduction software as AIDR-3D. (author)

320 Gb/s Single polarization OTDM Transmission over 80 km Standard Transmission Fiber

DEFF Research Database (Denmark)

Siahlo, Andrei; Seoane, Jorge; Clausen, Anders

2005-01-01

Optical time-division multiplexing (OTDM) is an attractive technique for increasing the capacity of optical transmission systems. 320 Gbit/s single-channel and single-polarization error-free transmission over continuous spans of either 80 km SMF or 77 km NZDSF are realized.......Optical time-division multiplexing (OTDM) is an attractive technique for increasing the capacity of optical transmission systems. 320 Gbit/s single-channel and single-polarization error-free transmission over continuous spans of either 80 km SMF or 77 km NZDSF are realized....

Preparation, Delivery, and Evaluation of Picomole Vapor Standards

Science.gov (United States)

2013-07-10

trace vapor standards is consistent production and a reliable means to transport and deliver the vapor to the analytical system being evaluated...8 32.6 8.92 Ethylbenzene 100-41-4 9.21 8.31x10-9 32.8 8.41 1,7-Octadiene 3710-30-3 22.5 4.74x10-9 31.8 10.7 Styrene 100-42-5 6.21 2.77x10-9 31.9

Análise produtiva e econômica do pepino japonês submetido a diferentes lâminas de irrigação Productive and economic analysis of japanese cucumber under different irrigation depths

Directory of Open Access Journals (Sweden)

Eduardo C. Oliveira

2011-07-01

Full Text Available Objetivou-se, com o presente trabalho, uma avaliação técnica e econômica da produtividade do pepino japonês (Cucumis sativus L. em função de diferentes lâminas de irrigação. O experimento foi instalado em casa de vegetação, utilizando-se de um delineamento inteiramente casualizado (DIC, com cinco tratamentos de reposição de água no solo (50, 75, 100, 125 e 150% e seis repetições. Os resultados permitiram concluir que, de maneira geral, o número e o peso dos frutos da cultura foram afetados pelo déficit e excesso hídrico, aplicados pelos tratamentos. A máxima produtividade obtida foi igual a 45.944 kg ha-1 com aplicação de 320 mm e a lâmina ótima econômica foi estimada em 319,5 mm, concluindose que, para o pepino japonês, maiores retornos econômicos são obtidos mantendo-se a cultura com umidade do solo próxima da capacidade de campo, repondo integralmente a quantidade de água consumida.This study had the aim to verify the economic feasibility of japanese cucumber (Cucumis sativus L. yield under different irrigation depths, cultivated in greenhouse. A completely randomized design (CRD, with five levels of replacement of irrigation water (50, 75, 100, 125 and 150% and six replications was used. The results showed that the number and fruit weight of crop were affected by treatments of water deficit and excess used for treatments. The maximum productivity obtained was equal to 45,944 kg ha-1 for a depth of 320 mm and the economic optimum irrigation depth was estimated at 319.5 mm, concluding that for the japanese cucumber higher economic returns are obtained by keeping the crop with soil water content near field capacity, restoring the full amount of water consumed.

New apparatus with high radiation energy between 320-460 nm: physical description and dermatological applications

International Nuclear Information System (INIS)

Mutzhas, M.F.; Holzle, E.; Hofmann, C.; Plewig, G.

1981-01-01

A new apparatus (UVASUN 5000) is presented with high-radiation energy between 320 to 460 nm. The measureable energy below 320 nm was shown to be many orders of magnitude too low to produce erythema. The radiator is a specially developed source for high uv-A intensity, housing a quartz bulb with a mixture of argon, mercury and metal-halides. At a skin-target distance of 0.2 m the size of the irradiated area is 0.35 x 0.35 m, and the measured mean uv-A intensity is about 1400 W. m-2 (140 mW . cm-2). The uv-A energy in the range of 320 to 400 nm is about 84% of the total radiation energy. Effects of very high doses of uv-A on human skin were studied. Following single uv-a applications the minimal tanning dose uv-A (MTD) and the immediate pigment darkening (IPD) dose of uv-A were established. The calculated IPD threshold time was 1.8 min at 0.2 m. Repeated exposure to this uv-A delivering system yields long lasting dark brown skin pigmentation without any clinical or histological signs of sunburn (uv-B) damage, epidermal hyperplasia or thickening of the stratum corneum. The instrument was also successfully used for photo-patch testing and reproduction of skin lesions of polymorphous light eruption. Minimal therapeutic results were seen in the phototherapy of vitiligo and inflammatory acne

Carotenoids quench evolution of excited species in epidermis exposed to UV-B (290-320 nm) light

International Nuclear Information System (INIS)

Mathews-Roth, M.M.

1986-01-01

Reactions involving singlet oxygen and other free radicals have been identified in epidermis containing either exogenous or endogenous photosensitizers, soaked in a singlet oxygen/free radical trap, and then exposed to visible or UV-A (320-400 nm) light. Such reactions can be quenched by the presence of the carotenoid pigments β-carotene and canthaxanthin which accumulate in epidermis after oral administration. It is reported that the carotenoid pigments β-carotene, canthaxanthin and phytoene accumulating in epidermis can also quench to some degree those photochemical reactions involving singlet oxygen and free radicals that occur when epidermis is exposed to the sunburn spectrum of light (UV-B, 290-320 nm). (author)

A history of the 2014 Minute 319 environmental pulse flow asdocumented by field measurements and satellite imagery

Science.gov (United States)

Nelson, Steven M.; Ramirez-Hernandez, Jorge; Rodriguez-Burgeueno, J. Eliana; Milliken, Jeff; Kennedy, Jeffrey R.; Zamora-Arroyo, Francisco; Schlatter, Karen; Santiago-Serrano, Edith; Carrera-Villa, Edgar

2017-01-01

As provided in Minute 319 of the U.S.-Mexico Water Treaty of 1944, a pulse flow of approximately 132 million cubic meters (mcm) was released to the riparian corridor of the Colorado River Delta over an eight-week period that began March 23, 2014 and ended May 18, 2014. Peak flows were released in the early part of the pulse to simulate a spring flood, with approximately 101.7 mcm released at Morelos Dam on the U.S.-Mexico border. The remainder of the pulse flow water was released to the riparian corridor via Mexicali Valley irrigation spillway canals, with 20.9 mcm released at Km 27 Spillway (41 km below Morelos Dam) and 9.3 mcm released at Km 18 Spillway (78 km below Morelos Dam). We used sequential satellite images, overflights, ground observations, water discharge measurements, and automated temperature, river stage and water quality loggers to document and describe the progression of pulse flow water through the study area. The rate of advance of the wetted front was slowed by infiltration and high channel roughness as the pulse flow crossed more than 40 km of dry channel which was disconnected from underlying groundwater and partially overgrown with salt cedar. High lag time and significant attenuation of flow resulted in a changing hydrograph as the pulse flow progressed to the downstream delivery points; two peak flows occurred in some lower reaches. The pulse flow advanced more than 120 km downstream from Morelos Dam to reach the Colorado River estuary at the northern end of the Gulf of California.

27 CFR 28.320 - Loss of beer and beer concentrate in transit.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Loss of beer and beer... AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Losses Beer and Beer Concentrate § 28.320 Loss of beer and beer concentrate in transit. (a) Losses not requiring inspection. When...

Project W-320 thermal hydraulic model benchmarking and baselining

International Nuclear Information System (INIS)

Sathyanarayana, K.

1998-01-01

Project W-320 will be retrieving waste from Tank 241-C-106 and transferring the waste to Tank 241-AY-102. Waste in both tanks must be maintained below applicable thermal limits during and following the waste transfer. Thermal hydraulic process control models will be used for process control of the thermal limits. This report documents the process control models and presents a benchmarking of the models with data from Tanks 241-C-106 and 241-AY-102. Revision 1 of this report will provide a baselining of the models in preparation for the initiation of sluicing

Interaction of 1.319 μm laser with skin: an optical-thermal-damage model and experimental validation

Science.gov (United States)

Jiao, Luguang; Yang, Zaifu; Wang, Jiarui

2014-09-01

With the widespread use of high-power laser systems operating within the wavelength region of approximately 1.3 to 1.4 μm, it becomes very necessary to refine the laser safety guidelines setting the exposure limits for the eye and skin. In this paper, an optical-thermal-damage model was developed to simulate laser propagation, energy deposition, heat transfer and thermal damage in the skin for 1.319 μm laser irradiation. Meanwhile, an experiment was also conducted in vitro to measure the tempreture history of a porcine skin specimen irradiated by a 1.319 μm laser. Predictions from the model included light distribution in the skin, temperature response and thermal damge level of the tissue. It was shown that the light distribution region was much larger than that of the incident laser at the wavelength of 1.319 μm, and the maximum value of the fluence rate located on the interior region of the skin, not on the surface. By comparing the calculated temperature curve with the experimentally recorded temperautre data, good agreement was shown betweeen them, which validated the numerical model. The model also indicated that the damage integral changed little when the temperature of skin tissue was lower than about 55 °C, after that, the integral increased rapidly and denatunation of the tissue would occur. Based on this model, we can further explore the damage mechanisms and trends for the skin and eye within the wavelength region of 1.3 μm to 1.4 μm, incorporating with in vivo experimental investigations.

Vitamin B12 deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse

Directory of Open Access Journals (Sweden)

Fernàndez-Roig Sílvia

2012-05-01

Full Text Available Abstract Background DNA methylation is an epigenetic phenomenon that can modulate gene function by up or downregulation of gene expression. Vitamin B12 and folate pathways are involved in the production of S-Adenosylmethionine, the universal methyl donor. Findings Brain vitamin B12 concentration and global DNA methylation was determined in transcobalamin receptor (TCblR/CD320 knock out (KO (n = 4 and control mice (n = 4 at 20–24 weeks of age. Median [IQR] brain vitamin B12 concentrations (pg/mg in TCblR/CD320 KO mice compared with control mice was 8.59 [0.52] vs 112.42 [33.12]; p CD320 KO compared with control mice (Median [IQR]: 0.31[0.16] % vs 0.55[0.15] %; p  Conclusions In TCblR/CD320 KO mice, brain vitamin B12 drops precipitously by as much as 90% during a 20 week period. This decrease is associated with a 40% decrease in global DNA methylation in the brain. Future research will reveal whether the disruption in gene expression profiles due to changes in DNA hypomethylation contribute to central nervous system pathologies that are frequently seen in vitamin B12 deficiency.

Coronary computed tomography angiography with 320-row detector and using the AIDR-3D: initial experience

International Nuclear Information System (INIS)

Sasdelli Neto, Roberto; Nomura, Cesar Higa; Macedo, Ana Carolina Sandoval; Bianco, Danilo Perussi; Kay, Fernando Uliana; Szarf, Gilberto; Teles, Gustavo Borges da Silva; Shoji, Hamilton; Santana Netto, Pedro Vieira; Passos, Rodrigo Bastos Duarte; Chate, Rodrigo Caruso; Ishikawa, Walther Yoshiharu; Lima, Joao Paulo Bacellar Costa; Rocha, Marcelo Assis; Marcos, Vinicius Neves; Funari, Marcelo Buarque de Gusmao; Failla, Bruna Bonaventura

2013-01-01

Coronary computed tomography angiography (coronary CTA) is a powerful non-invasive imaging method to evaluate coronary artery disease. Nowadays, coronary CTA estimated effective radiation dose can be dramatically reduced using state-of-the-art scanners, such as 320-row detector CT (320-CT), without changing coronary CTA diagnostic accuracy. To optimize and further reduce the radiation dose, new iterative reconstruction algorithms were released recently by several CT manufacturers, and now they are used routinely in coronary CTA. This paper presents our first experience using coronary CTA with 320-CT and the Adaptive Iterative Dose Reduction 3D (AIDR-3D). In addition, we describe the current indications for coronary CTA in our practice as well as the acquisition standard protocols and protocols related to CT application for radiation dose reduction. In conclusion, coronary CTA radiation dose can be dramatically reduced following the 'as low as reasonable achievable' principle by combination of exam indication and well-documented technics for radiation dose reduction, such as beta blockers, low-kV, and also the newest iterative dose reduction software as AIDR-3D. (author)

318-MHz variability of complete samples of extragalactic radio sources. II

International Nuclear Information System (INIS)

Dennison, B.; Broderick, J.J.; Ledden, J.E.; O'Dell, S.L.; Condon, J.J.

1981-01-01

We report the remainder of two- and three-epoch 318-MHz observations of extragalactic sources in samples complete to 3 Jy at 1400 MHz and 1 Jy at 5000 MHz. From analysis of this low-frequency variability survey, we find that steep-spectrum (α> or =0.5) sources do not appear to vary, but about 40% of all flat-spectrum (α<0.5) sources exhibit low-frequency variability exceeding 8% over approx.5 yr. Among the flat-spectrum sources, those with inverted spectra show the largest fractional variations. We also find that the incidence of low-frequency variability is strongly correlated with the determination that a source is an optically violent variable. These statistical properties are consistent with models invoking relativistic beaming of radio and optical emission

9 CFR 319.310 - Lima beans with ham in sauce, beans with ham in sauce, beans with bacon in sauce, and similar...

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Lima beans with ham in sauce, beans with ham in sauce, beans with bacon in sauce, and similar products. 319.310 Section 319.310 Animals and....310 Lima beans with ham in sauce, beans with ham in sauce, beans with bacon in sauce, and similar...

Using 80 kVp on a 320-row scanner for hepatic multiphasic CT reduces the contrast dose by 50 % in patients at risk for contrast-induced nephropathy

Energy Technology Data Exchange (ETDEWEB)

Taguchi, Narumi; Oda, Seitaro; Utsunomiya, Daisuke; Nakaura, Takeshi; Imuta, Masanori; Yamamura, Sadahiro; Yuki, Hideaki; Kidoh, Masafumi; Hirata, Kenichiro; Namimoto, Tomohiro; Yamashita, Yasuyuki [Kumamoto University, Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto (Japan); Funama, Yoshinori [Kumamoto University, Department of Medical Physics, Faculty of Life Sciences, Kumamoto (Japan); Hatemura, Masahiro; Kai, Noriyuki [Kumamoto University Hospital, Department of Central Radiology, Kumamoto (Japan)

2017-02-15

We evaluated the effects of a low contrast material (CM) dose protocol using 80-kVp on the image quality of hepatic multiphasic CT scans acquired on a 320-row CT scanner. We scanned 30 patients with renal insufficiency (eGFR < 45 mL/min/1.73 m{sup 2}) using 80-kVp and a CM dose of 300mgI/kg. Another 30 patients without renal insufficiency (eGFR > 60 mL/min/1.73 m{sup 2}) were scanned with the conventional 120-kVp protocol and the standard CM dose of 600mgI/kg. Quantitative image quality parameters, i.e. CT attenuation, image noise, and the contrast-to-noise ratio (CNR) were compared and the visual image quality was scored on a four-point scale. The volume CT dose index (CTDI{sub vol}) and the size-specific dose estimate (SSDE) recorded with the 80- and the 120-kVp protocols were also compared. Image noise and contrast enhancement were equivalent for the two protocols. There was no significant difference in the CNR of all anatomic sites and in the visual scores for overall image quality. The CTDI{sub vol} and SSDE were approximately 25-30 % lower under the 80-kVp protocol. Hepatic multiphase CT using 80-kVp on a 320-row CT scanner allowed for a decrease in the CM dose and a reduction in the radiation dose without image quality degradation in patients with renal insufficiency. (orig.)

20 CFR 405.320 - Administrative law judge hearing procedures-general.

Science.gov (United States)

2010-04-01

...) Conduct of the hearing. The administrative law judge will decide the order in which the evidence will be... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Administrative law judge hearing procedures... PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Administrative Law Judge Hearing § 405.320...

9 CFR 319.10 - Requirements for substitute standardized meat food products named by use of an expressed nutrient...

Science.gov (United States)

2010-01-01

... INSPECTION AND CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION General § 319.10... identity, but that do not comply with the established standard because of a compositional deviation that... for roller grilling”). Deviations from the ingredient provisions of the standard must be the minimum...

Project W-320, 241-C-106 sluicing: Construction specification W-320-C1

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits

Effect of a magnetic field on the permittivity of 80%La0.7Sr0.3MnO3/20%GeO2 composite

Science.gov (United States)

Kabirov, Yu. V.; Gavrilyachenko, V. G.; Bogatin, A. S.; Sitalo, E. I.; Yatsenko, V. K.

2018-01-01

The dielectric properties of a magnetoresistive conducting two-phase 80%La0.7Sr0.3MnO3/20%GeO2 (wt %) composite have been studied near the percolation threshold in magnetic fields from 0 to 15 kOe at frequencies of the measurement field from 5 kHz to 1 MHz. The samples have inductive impedances; i.e., their permittivities can be considered negative due to a high conductivity in this frequency range. The permittivity increases in magnitude in magnetic field, and the values of the magnetodielectric coefficient reach 23% at room temperature. The reasons for the effect of magnetic field on the dielectric permittivity of samples are discussed.

Assessing regional cerebral blood flow in depression using 320-slice computed tomography.

Directory of Open Access Journals (Sweden)

Yiming Wang

Full Text Available While there is evidence that the development and course of major depressive disorder (MDD symptomatology is associated with vascular disease, and that there are changes in energy utilization in the disorder, the extent to which cerebral blood flow is changed in this condition is not clear. This study utilized a novel imaging technique previously used in coronary and stroke patients, 320-slice Computed-Tomography (CT, to assess regional cerebral blood flow (rCBF in those with MDD and examine the pattern of regional cerebral perfusion. Thirty nine participants with depressive symptoms (Hamilton Depression Rating Scale 24 (HAMD24 score > 20, and Self-Rating Depression Scale (SDS score > 53 and 41 healthy volunteers were studied. For all subjects, 3 ml of venous blood was collected to assess hematological parameters. Transcranial Doppler (TCD ultrasound was utilized to measure parameters of cerebral artery rCBFV and analyse the Pulsatility Index (PI. 16 subjects (8 =  MDD; 8 =  healthy also had rCBF measured in different cerebral artery regions using 320-slice CT. Differences among groups were analyzed using ANOVA and Pearson's tests were employed in our statistical analyses. Compared with the control group, whole blood viscosity (including high\\middle\\low shear rateand hematocrit (HCT were significantly increased in the MDD group. PI values in different cerebral artery regions and parameters of rCBFV in the cerebral arteries were decreased in depressive participants, and there was a positive relationship between rCBFV and the corresponding vascular rCBF in both gray and white matter. rCBF of the left gray matter was lower than that of the right in MDD. Major depression is characterized by a wide range of CBF impairments and prominent changes in gray matter blood flow. 320-slice CT appears to be a valid and promising tool for measuring rCBF, and could thus be employed in psychiatric settings for biomarker and treatment response purposes.

Project W-320, 241-C-106 sluicing supporting documentation bibliography

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

This supporting document has been prepared to make the listing of documentation used to develop, or in support of Project W-320, readily retrievable. All documents are sorted by document number and list the document type. Tank 241-C-106 has been included on the High Heat Load Watch List

Processing and Characterization of Functionally Graded Aluminum (A319)—SiCp Metallic Composites by Centrifugal Casting Technique

Science.gov (United States)

Jayakumar, E.; Jacob, Jibin C.; Rajan, T. P. D.; Joseph, M. A.; Pai, B. C.

2016-08-01

Functionally graded materials (FGM) are successfully adopted for the design and fabrication of engineering components with location-specific properties. The present study describes the processing and characterization of A319 Aluminum functionally graded metal matrix composites (FGMMC) with 10 and 15 wt pct SiCp reinforcements. The liquid stir casting method is used for composite melt preparation followed by FGMMC formation by vertical centrifugal casting method. The process parameters used are the mold preheating temperature of 523 K (250 °C), melt pouring temperature of 1013 K (740 °C), and mold rotation speed of 1300 rpm. The study analyzes the distribution and concentration of reinforcement particles in the radial direction of the FGMMC disk along with the effects of gradation on density, hardness, mechanical strength, the variation in coefficient of thermal expansion and the wear resistance properties at different zones. Microstructures of FGMMC reveal an outward radial gradient distribution of reinforcements forming different zones. Namely, matrix-rich inner, transition, particles-rich outer, and chill zone of a few millimeters thick at the outer most periphery of the casting are formed. From 10-FGM, a radial shift in the position of SiCp maxima is observed in 15-FGM casting. The mechanical characterization depicts enhanced properties for the particle-rich zone. The hardness shows a graded nature in correlation with particle concentration and a maximum of 94.4 HRB has been obtained at the particle-rich region of 15-FGM. In the particle-rich zone, the lowest CTE value of 20.1 µm/mK is also observed with a compressive strength of 650 MPa and an ultimate tensile strength of 279 MPa. The wear resistance is higher at the particle-rich zone of the FGMMC.

A Methodology to Measure the Cost of a Single Outpatient Visit in the Family Practice Clinic

Science.gov (United States)

1986-07-01

17,598 EDEA Other Base Support 116 " i 25,480 453 EDCA Maint Real Prop 116 Is 25,480 4,652 EDDA Minor Const 116 " H 25,480 460 EDFA Leases/Rentals 116...Engineer Liaison 116 22,319 177 EDBA Utilities 116 " " 22,319 15,414 EDEA Other Base Support 116 " " 22,319 398 EDCA Maint Real Prop 116 22,319 4,075 EDDA ...Liaison 116 4,301 34 EDBA Utilities 116 " " 4,301 2,970 EDEA Other Base Support 116 " " 4,301 76 EDCA Maint Real Prop 116 " " 4,301 785 EDDA Minor Const 116

New apparatus with high radiation energy between 320 to 460 nm: physical description and dermatological applications

International Nuclear Information System (INIS)

Mutzhas, M.F.; Holzle, E.; Hofmann, C.; Plewig, G.

1981-01-01

A new apparatus (UVASUN 5000) is presented with high radiation energy between 320 to 460 nm. The radiator is a specially developed source for high uv-A intensity, housing a quartz bulb with a mixture of argon, mercury and metal-halides. The uv-A energy in the range of 320 to 400 nm is about 84% of the total radiation energy. Effects of very high doses of uv-A on human skin were studied. Following single uv-A applications the minimal tanning dose uv-A (MTD) and the immediate pigment darkening (IPD) dose of uv-A were established. Repeated exposure to this uv-A delivering system yields long lasting dark brown skin pigmentation without any clinical or histological signs of sunburn (uv-B) damage, epidermal hyperplasia or thickening of the stratum corneum. Minimal therapeutic results were seen in the phototherapy of vitiligo and inflammatory acne

Film Cooling in Fuel Rich Environments

Science.gov (United States)

2013-03-27

Heat Release Analysis . . . . . . . 89 4.26 Enhanced Blue Value Photographs for Flame Length Quantification, M=2.0, φ = 1.175, Single Row, Triple Row...Photographs for Flame Length . . . . . . . . . . . . . . 105 B.1 Charts Used to Calculate Trip Height . . . . . . . . . . . . . . . . . . . . . . . 107 B...coolant and quantification of flame length . The side window is shown in Figure 3.20 with a ruler used to calibrate the images. 51 Figure 3.18: Spanwise

Evaluation of novel oral vaccine candidates and validation of a caprine model of Johne's disease

Science.gov (United States)

Hines, Murray E.; Turnquist, Sue E.; Ilha, Marcia R. S.; Rajeev, Sreekumari; Jones, Arthur L.; Whittington, Lisa; Bannantine, John P.; Barletta, Raúl G.; Gröhn, Yrjö T.; Katani, Robab; Talaat, Adel M.; Li, Lingling; Kapur, Vivek

2014-01-01

Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a major threat to the dairy industry and possibly some cases of Crohn's disease in humans. A MAP vaccine that reduced of clinical disease and/or reduced fecal shedding would aid in the control of JD. The objectives of this study were (1) to evaluate the efficacy of 5 attenuated strains of MAP as vaccine candidates compared to a commercial control vaccine using the protocol proposed by the Johne's Disease Integrated Program (JDIP) Animal Model Standardization Committee (AMSC), and (2) to validate the AMSC Johne's disease goat challenge model. Eighty goat kids were vaccinated orally twice at 8 and 10 weeks of age with an experimental vaccine or once subcutaneously at 8 weeks with Silirum® (Zoetis), or a sham control oral vaccine at 8 and 10 weeks. Kids were challenged orally with a total of approximately 1.44 × 109 CFU divided in two consecutive daily doses using MAP ATCC-700535 (K10-like bovine isolate). All kids were necropsied at 13 months post-challenge. Results indicated that the AMSC goat challenge model is a highly efficient and valid model for JD challenge studies. None of the experimental or control vaccines evaluated prevented MAP infection or eliminated fecal shedding, although the 329 vaccine lowered the incidence of infection, fecal shedding, tissue colonization and reduced lesion scores, but less than the control vaccine. Based on our results the relative performance ranking of the experimental live-attenuated vaccines evaluated, the 329 vaccine was the best performer, followed by the 318 vaccine, then 316 vaccine, 315 vaccine and finally the 319 vaccine was the worst performer. The subcutaneously injected control vaccine outperformed the orally-delivered mutant vaccine candidates. Two vaccines (329 and 318) do reduce presence of JD gross and microscopic lesions, slow progression of disease, and one vaccine (329) reduced fecal shedding and tissue colonization. PMID

Evaluation of Novel Oral Vaccine Candidates and Validation of a Caprine Model of Johne's Disease

Directory of Open Access Journals (Sweden)

Murray E. Hines

2014-03-01

Full Text Available Johne’s disease (JD caused by Mycobacterium avium subspecies paratuberculosis (MAP is a major threat to the dairy industry and possibly some cases of Crohn’s disease in humans. A MAP vaccine that reduced of clinical disease and/or reduced fecal shedding would aid in the control of JD. The objectives of this study were 1 to evaluate the efficacy of 5 attenuated strains of MAP as vaccine candidates compared to a commercial control vaccine using the protocol proposed by the Johne’s Disease Integrated Program (JDIP Animal Model Standardization Committee (AMSC, and 2 to validate the AMSC Johne’s disease goat challenge model. Eighty goat kids were vaccinated orally twice at 8 and 10 weeks of age with an experimental vaccine or once subcutaneously at 8 weeks with Silirum® (Zoetis, or a sham control oral vaccine at 8 and 10 weeks. Kids were challenged orally with a total of approximately 1.44 X 10^9 CFU divided in 2 consecutive daily doses using MAP ATCC-700535 (K10-like bovine isolate. All kids were necropsied at 13 months post challenge. Results indicated that the AMSC goat challenge model is a highly efficient and valid model for JD challenge studies. None of the experimental or control vaccines evaluated prevented MAP infection or eliminated fecal shedding, although the 329 vaccine lowered the incidence of infection, fecal shedding, tissue colonization and reduced lesion scores, but less than the control vaccine. Based on our results the relative performance ranking of the experimental live-attenuated vaccines evaluated, the 329 vaccine was the best performer, followed by the 318 vaccine, then 316 vaccine, 315 vaccine and finally the 319 vaccine was the worst performer. The subcutaneously injected control vaccine outperformed the orally-delivered mutant vaccine candidates. Two vaccines (329 and 318 do reduce presence of JD gross and microscopic lesions, slow progression of disease, and one vaccine (329 reduced fecal shedding and tissue

Project W-320, 241-C-106 sluicing piping calculations, Volume 7

International Nuclear Information System (INIS)

Bailey, J.W.

1998-01-01

The object of this report is to calculate the hydraulic forces imposed at the sluicer nozzle. This is required by Project W-320 waste retrieval for tank 241-C-106. The method of analysis used is Bernoulli's momentum equation for stead flow

Method of forming a nanocluster comprising dielectric layer and device comprising such a layer

NARCIS (Netherlands)

2009-01-01

A method of forming a dielectric layer (330) on a further layer (114, 320) of a semiconductor device (300) is disclosed. The method comprises depositing a dielectric precursor compound and a further precursor compound over the further layer (114, 320), the dielectric precursor compound comprising a

Hydrogeological characteristics and hydraulic discharge forecast of Uranium Deposit No.320

International Nuclear Information System (INIS)

Hao Fulin.

1987-01-01

The water and heat sources of Uranium Deposit No.320 have been discussed according to the water-controlling specific features of the regional strata and geological structures(including water transmitting and bearing structures), which provide evidence for the forecasting of hydraulic discharge. On the basis of the hydrogeological study of the deposit, the author draws up a plan for combining the mine drainage with the urban water supply and making comprehensively use of the thermal water resource

Methodology for the evaluation of tolerability of defects in WWER-1000/V-320 reactor pressure vessels

International Nuclear Information System (INIS)

Brumovsky, M.; Horacek, L.; Ruscak, M.

1996-05-01

The methodology provides guidelines for the assessment of tolerability of defects found during in-service inspection of the base material and overlay of WWER-1000/V-320 type reactor pressure vessels. With regard to the method of calculating the tolerability of defects and rules for the preparation and implementation of repairs, this methodology can also find use in the assessment of tolerability of defects in selected facilities of WWER-1000/V-320 type nuclear power plants provided that adequate input data concerning the materials, manufacturing technology, and operating load regime are available and that the facilities are made of ferrite/bainite type steels. This methodology should serve as a binding document underlying the development of a technical approach to provisions for a further operation of facilities in which intolerable defects have been found by nondestructive testing. (author)

Project W320 52-inch diameter equipment container load test: Test report

International Nuclear Information System (INIS)

Bellomy, J.R.

1995-01-01

This test report summarizes testing activities and documents the results of the load tests performed on-site and off-site to structural qualify the 52-inch equipment containers designed and fabricated under Project W-320

Intraventricular Neurocysticercosis: Experience and Long-Term Outcome from a Tertiary Referral Center in the United States.

Science.gov (United States)

Nash, Theodore E; Ware, JeanAnne M; Mahanty, Siddhartha

2018-04-23

Ventricular involvement in neurocysticercosis (NCC), a common serious manifestation of NCC, has distinct clinical presentations, complications, and treatments primarily because of partial or complete obstruction of the cerebrospinal fluid (CSF) flow by Taenia solium cysts. We review the clinical course, treatments, and long-term outcomes in 23 of 121 (19.0%) total NCC patients with ventricular cysts referred to the National Institutes of Health from 1985 to the October 2017. Patients had a median age of 31.8 (range: 22.4-52.6 years), were 60.9% male, diagnosed a median of 6.5 years (range: 0.17-16 years) after immigration, and were followed for a median of 3.6 years (range: 0.1-30.5 years). Other forms and manifestations of NCC were present in 73.9% (17/23). The fourth ventricle was involved in a majority (15/23, 65.2%) resulting in hydrocephalus (73.9%), ventriculitis, and periventricular edema (7/23, 30.4%). Cystectomy was accomplished in 60.9%, usually by removal of a fourth ventricular cyst through a suboccipital craniotomy. Nonresectable cysts were treated medically. Ventriculoperitoneal shunts were inserted in 43.5% (10/23) and failed in four, three from infection. Other complications included surgically induced injuries (4/23, 17.4%) and entrapment of a lateral ventricle (2/23, 8.7%). Despite a common severe early course, 90.9% (20/22) stabilized without recurrence, 15% (3/20) complained of mild-to-moderate neurological complaints, and 15% (3/20) were significantly disabled. Four patients who underwent removal of ventricular cysts without significant other NCC and who received with no cysticidal treatment became CSF cestode antigen negative without recurrence indicating that after successful extraction of cysts, additional cysticidal treatment may not be needed.

miR319, miR390, and miR393 Are Involved in Aluminum Response in Flax (Linum usitatissimum L.).

Science.gov (United States)

Dmitriev, Alexey A; Kudryavtseva, Anna V; Bolsheva, Nadezhda L; Zyablitsin, Alexander V; Rozhmina, Tatiana A; Kishlyan, Natalya V; Krasnov, George S; Speranskaya, Anna S; Krinitsina, Anastasia A; Sadritdinova, Asiya F; Snezhkina, Anastasiya V; Fedorova, Maria S; Yurkevich, Olga Yu; Muravenko, Olga V; Belenikin, Maxim S; Melnikova, Nataliya V

2017-01-01

Acid soils limit agricultural production worldwide. Major reason of crop losses in acid soils is the toxicity of aluminum (Al). In the present work, we investigated expression alterations of microRNAs in flax ( Linum usitatissimum L.) plants under Al stress. Flax seedlings of resistant (TMP1919 and G1071/4_k) and sensitive (Lira and G1071/4_o) to Al cultivars and lines were exposed to AlCl 3 solution for 4 and 24 hours. Twelve small RNA libraries were constructed and sequenced using Illumina platform. In total, 97 microRNAs from 18 conserved families were identified. miR319, miR390, and miR393 revealed expression alterations associated with Al treatment of flax plants. Moreover, for miR390 and miR393, the alterations were distinct in sensitive and resistant to Al genotypes. Expression level changes of miR319 and miR390 were confirmed using qPCR analysis. In flax, potential targets of miR319 are TCPs, miR390-TAS3 and GRF5, and miR393-AFB2-coding transcripts. TCPs, TAS3, GRF5, and AFB2 participate in regulation of plant growth and development. The involvement of miR319, miR390, and miR393 in response to Al stress in flax was shown here for the first time. We speculate that these microRNAs play an important role in Al response via regulation of growth processes in flax plants.

Solubility of gallic acid in liquid mixtures of (ethanol + water) from (293.15 to 318.15) K

International Nuclear Information System (INIS)

Noubigh, Adel; Jeribi, Chokri; Mgaidi, Arbi; Abderrabba, Manef

2012-01-01

Graphical abstract: Solubility of gallic acid vs the mole fraction of ethanol (0.0 to 1) on a solute-free basis in ethanol + water at different temperatures/K. □, 293.15; Δ, 298.15; ◊, 303.15; line calculated by equation. Highlights: ► Solubilities of gallic acid in binary mixtures were determined over the temperatures range (293.15 to 318.15) K. ► The gallic acid solubility in mixed solvents presents a maximum-solubility effect. ► Two empirical equations were proposed to correlate the solubility Data. ► The thermodynamic properties were determined. - Abstract: The solubility of gallic acid in (water + ethanol) binary solvents was determined from (293.15 to 318.15) K at atmospheric pressure using a thermostatted reactor and UV/vis spectrophotometer analysis. The effects of binary solvents composition and temperature on the solubility were discussed. It was found that gallic acid solubility in (water + ethanol) mixed solvents presents a maximum-solubility effect. Two empirical equations were proposed to correlate the solubility data. The calculated solubilities show good agreement with the experimental data within the studied temperature range. Using the experimentally measured solubilities, the thermodynamic properties of dissolution of the gallic acid such as Gibbs energy (Δ sol G°), molar enthalpy of dissolution (Δ sol H°), and molar entropy of dissolution (Δ sol S°) were calculated.

Don’t be fooled by a name: a reply to Thompson and Davis

Czech Academy of Sciences Publication Activity Database

Hulme, P. E.; Pyšek, Petr; Duncan, R. P.

2011-01-01

Roč. 26, č. 7 (2011), s. 318-318 ISSN 0169-5347 Institutional research plan: CEZ:AV0Z60050516 Keywords : biological invasions * species traits * New Zealand Subject RIV: EF - Botanics Impact factor: 15.748, year: 2011

47 CFR 80.320 - Radiotelephone distress call and message transmission procedure.

Science.gov (United States)

2010-10-01

... by its call sign or name, to permit direction-finding stations to determine its position. This... 47 Telecommunication 5 2010-10-01 2010-10-01 false Radiotelephone distress call and message... Procedures Distress, Alarm, Urgency and Safety Procedures § 80.320 Radiotelephone distress call and message...

microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells

DEFF Research Database (Denmark)

Hamam, D; Ali, D; Vishnubalaji, R

2014-01-01

The molecular mechanisms promoting lineage-specific commitment of human mesenchymal (skeletal or stromal) stem cells (hMSCs) into adipocytes (ADs) are not fully understood. Thus, we performed global microRNA (miRNA) and gene expression profiling during adipocytic differentiation of h...... differentiation and accelerated formation of mature ADs in ex vivo cultures. Integrated analysis of bioinformatics and global gene expression profiling in miR-320c overexpressing cells and during adipocytic differentiation of hMSC identified several biologically relevant gene targets for miR-320c including RUNX2...

Effect of Fe content, cooling rate and porosity on the tensile properties of cast 319 and 356 aluminum alloys

International Nuclear Information System (INIS)

Ma, Z.; Samuel, A.M.; Samuel, F.H.; Doty, H.W.; Valtierra, S.

2002-01-01

The present study was carried out to investigate the effects of Fe content, cooling rate and porosity on the tensile properties of cast 319 and 356 alloys. Both experimental and industrial 319 alloys (containing 0.1 and 0.4 wt% Mg) and industrial 356 alloys were used, with 200-300 ppm strontium additions to study the modification effect. The Fe content was varied from 0.2 to 0.8 wt% in the 319 alloys, and from 0.1 to 0.6 wt% in the 356 alloy in keeping with Fe levels observed in industry. An end-chilled mold was employed to obtain directionally solidified castings, where the cooling rate varied with the height of the casting. Tensile and microstructural samples were sectioned at heights corresponding to dendrite arm spacings of ∼23 to ∼83 μm. The microstructures were examined using optical- and scanning electron microscopy. The effect of Fe content and cooling rate was investigated through measurements of the β-Al 5 FeSi platelets, using image analysis. Porosity measurements were also made. Phase identification was done using EPMA, EDX and XRD. The results show that the β-Al 5 FeSi platelet size has a significant effect on ductility and tensile strength up to sizes of ∼100 μm in the 319 alloys and ∼70 μm in the 356 alloy, but has no significant effect on the yield strength. While tensile properties are interpreted by means of UTS vs. log Elongation plots (after the Quality index concept of Drouzy et al. (5)), in the present study, the properties for all sample conditions were best interpreted by means of log UTS vs. log Elongation plots, where the properties increased linearly within low cooling rate-high Fe and high cooling rate-low Fe condition extremities. The results are explained in terms of the β-Al 5 FeSi platelet size and porosity values obtained. (author)

A comparison of entropy balance and probability weighting methods to generalize observational cohorts to a population: a simulation and empirical example.

Science.gov (United States)

Harvey, Raymond A; Hayden, Jennifer D; Kamble, Pravin S; Bouchard, Jonathan R; Huang, Joanna C

2017-04-01

We compared methods to control bias and confounding in observational studies including inverse probability weighting (IPW) and stabilized IPW (sIPW). These methods often require iteration and post-calibration to achieve covariate balance. In comparison, entropy balance (EB) optimizes covariate balance a priori by calibrating weights using the target's moments as constraints. We measured covariate balance empirically and by simulation by using absolute standardized mean difference (ASMD), absolute bias (AB), and root mean square error (RMSE), investigating two scenarios: the size of the observed (exposed) cohort exceeds the target (unexposed) cohort and vice versa. The empirical application weighted a commercial health plan cohort to a nationally representative National Health and Nutrition Examination Survey target on the same covariates and compared average total health care cost estimates across methods. Entropy balance alone achieved balance (ASMD ≤ 0.10) on all covariates in simulation and empirically. In simulation scenario I, EB achieved the lowest AB and RMSE (13.64, 31.19) compared with IPW (263.05, 263.99) and sIPW (319.91, 320.71). In scenario II, EB outperformed IPW and sIPW with smaller AB and RMSE. In scenarios I and II, EB achieved the lowest mean estimate difference from the simulated population outcome ($490.05, $487.62) compared with IPW and sIPW, respectively. Empirically, only EB differed from the unweighted mean cost indicating IPW, and sIPW weighting was ineffective. Entropy balance demonstrated the bias-variance tradeoff achieving higher estimate accuracy, yet lower estimate precision, compared with IPW methods. EB weighting required no post-processing and effectively mitigated observed bias and confounding. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Microstructure and Mechanical Properties of Heat-Treated B319 Alloy Diesel Cylinder Heads

Science.gov (United States)

Chaudhury, S. K.; Apelian, D.; Meyer, P.; Massinon, D.; Morichon, J.

2015-07-01

coarsening rate of precipitates near to the periphery of the dendrite is greater than in the center. This is because the Al matrix region close to the eutectic Si particles is subjected to in situ thermal stresses, which is generated due to the thermal mismatch between Al and Si particles. Thermal stress is highest at the Si/Al interface and decreases significantly away from the Al/Si interface. The precipitation and growth rate of the alloy aged in fluidized bed is greater than in conventional furnace. This is because heating rates of casting in fluidized bed (FB) are greater than conventional furnace, which result in greater precipitation rate. This study establishes a correlation between structure, thermal processing, and property of B319 alloy treated to various heat treatments. Reasonably good mechanical properties were obtained in less time using fluidized bed furnace. This work clearly demonstrates the significant potential of FB to save time and energy.

7 CFR 319.56-44 - Untreated grapefruit, sweet oranges, and tangerines from Mexico for processing.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Untreated grapefruit, sweet oranges, and tangerines... QUARANTINE NOTICES Fruits and Vegetables § 319.56-44 Untreated grapefruit, sweet oranges, and tangerines from Mexico for processing. Untreated grapefruit (Citrus paradisi), sweet oranges (Citrus sinensis), and...

Project management plan for Project W-320, Tank 241-C-106 sluicing. Revision 2

Energy Technology Data Exchange (ETDEWEB)

Phillips, D.R.

1994-07-01

A major mission of the US Department of Energy (DOE) is the permanent disposal of Hanford Site defense wastes by utilizing safe, environmentally acceptable, and cost-effective disposal methods that meet applicable regulations. The Tank Waste Remediation System (TWRS) Program was established at the Hanford Site to manage and control activities specific to the remediation of safety watch list tanks, including high-heat-producing tanks, and for the ultimate characterization, retrieval, pretreatment, and disposal of the low- and high-level fractions of the tank waste. Project W-320, Tank 241-C-106 Sluicing, provides the methodology, equipment, utilities, and facilities necessary for retrieving the high-heat waste from single-shell tank (SST) 24-C-106. Project W-320 is a fiscal year (FY) 1993 expense-funded major project, and has a design life of 2 years. Retrieval of the waste in tank 241-C-106 will be accomplished through mobilization of the sludge into a pumpable slurry using past-practice sluicing. The waste is then transferred directly to a double-shell tank for interim storage, subsequent pretreatment, and eventual disposal. A detailed description of the management organization and responsibilities of all participants is presented in this document.

Project management plan for Project W-320, Tank 241-C-106 sluicing. Revision 2

International Nuclear Information System (INIS)

Phillips, D.R.

1994-07-01

A major mission of the US Department of Energy (DOE) is the permanent disposal of Hanford Site defense wastes by utilizing safe, environmentally acceptable, and cost-effective disposal methods that meet applicable regulations. The Tank Waste Remediation System (TWRS) Program was established at the Hanford Site to manage and control activities specific to the remediation of safety watch list tanks, including high-heat-producing tanks, and for the ultimate characterization, retrieval, pretreatment, and disposal of the low- and high-level fractions of the tank waste. Project W-320, Tank 241-C-106 Sluicing, provides the methodology, equipment, utilities, and facilities necessary for retrieving the high-heat waste from single-shell tank (SST) 24-C-106. Project W-320 is a fiscal year (FY) 1993 expense-funded major project, and has a design life of 2 years. Retrieval of the waste in tank 241-C-106 will be accomplished through mobilization of the sludge into a pumpable slurry using past-practice sluicing. The waste is then transferred directly to a double-shell tank for interim storage, subsequent pretreatment, and eventual disposal. A detailed description of the management organization and responsibilities of all participants is presented in this document

29 CFR 1952.320 - Description of the plan as initially approved.

Science.gov (United States)

2010-07-01

... of Labor. (2) The plan defines the covered occupational safety and health issues as defined by the... Section 1952.320 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH... existing enabling legislation and the Indiana Occupational Safety and Health Act (IC 1971, 22-8-1.1 et seq...

Project W-320, tank 241-C-106 sluicing acceptance for beneficial use

International Nuclear Information System (INIS)

BAILEY, J.W.

1999-01-01

The purpose of this document is to identify the Project W-320 Chiller Documentation required to be turned over from the Projects Organization to Tank Farm Operations as part of the acceptance of the new equipment for beneficial use

Thermochemical study of aqueous solutions of lithium diclofenac at 293.15-318.15 K

Science.gov (United States)

Manin, N. G.; Perlovich, G. L.; Fini, A.

2013-04-01

The enthalpies of solution and dilution of aqueous solutions of lithium diclofenac (LiDC) are measured in the concentration range of 0.002-0.047 m at 293.15, 298.15, 308.15, and 318.5 K using an isoperibolic calorimeter. The heat capacity of solid LiDC in the temperature range of 273.15-373.15 K is determined using a DSC 204 F1 Phoenix differential scanning calorimeter (NETZSCH, Germany). The virial coefficients of the enthalpy characteristics of a water-LiDC solution are derived in terms of the Pitzer model to calculate a wide range of thermodynamic properties of both the solution and its components. Changes in these characteristics as a function of concentration and temperature are discussed.

Unique in vitro and in vivo thrombopoietic activities of ingenol 3,20 dibenzoate, a Ca(++-independent protein kinase C isoform agonist.

Directory of Open Access Journals (Sweden)

Frederick K Racke

Full Text Available Thrombopoiesis following severe bone marrow injury frequently is delayed, thereby resulting in life-threatening thrombocytopenia for which there are limited treatment options. The reasons for these delays in recovery are not well understood. Protein kinase C (PKC agonists promote megakaryocyte differentiation in leukemia cell lines and primary cells. However, little is known about the megakaryopoietic effects of PKC agonists on primary CD34+ cells grown in culture or in vivo. Here we present evidence that the novel PKC isoform-selective agonist 3,20 ingenol dibenzoate (IDB potently stimulates early megakaryopoiesis of human CD34+ cells. In contrast, broad spectrum PKC agonists failed to do so. In vivo, a single intraperitoneal injection of IDB selectively increased platelets in mice without affecting hemoglobin or white counts. Finally, IDB strongly mitigated radiation-induced thrombocytopenia, even when administered 24 hours after irradiation. Our data demonstrate that novel PKC isoform agonists such as IDB may represent a unique therapeutic strategy for accelerating the recovery of platelet counts following severe marrow injury.

7 CFR 319.56-27 - Fuji variety apples from Japan and the Republic of Korea.

Science.gov (United States)

2010-01-01

... Republic of Korea, by an APHIS inspector and an inspector from the national plant protection agency of... in § 319.56-3. (c) Trust fund agreements. The national plant protection agency of the exporting...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Fruits...

SimDoseCT: dose reporting software based on Monte Carlo simulation for a 320 detector-row cone-beam CT scanner and ICRP computational adult phantoms

Science.gov (United States)

Cros, Maria; Joemai, Raoul M. S.; Geleijns, Jacob; Molina, Diego; Salvadó, Marçal

2017-08-01

This study aims to develop and test software for assessing and reporting doses for standard patients undergoing computed tomography (CT) examinations in a 320 detector-row cone-beam scanner. The software, called SimDoseCT, is based on the Monte Carlo (MC) simulation code, which was developed to calculate organ doses and effective doses in ICRP anthropomorphic adult reference computational phantoms for acquisitions with the Aquilion ONE CT scanner (Toshiba). MC simulation was validated by comparing CTDI measurements within standard CT dose phantoms with results from simulation under the same conditions. SimDoseCT consists of a graphical user interface connected to a MySQL database, which contains the look-up-tables that were generated with MC simulations for volumetric acquisitions at different scan positions along the phantom using any tube voltage, bow tie filter, focal spot and nine different beam widths. Two different methods were developed to estimate organ doses and effective doses from acquisitions using other available beam widths in the scanner. A correction factor was used to estimate doses in helical acquisitions. Hence, the user can select any available protocol in the Aquilion ONE scanner for a standard adult male or female and obtain the dose results through the software interface. Agreement within 9% between CTDI measurements and simulations allowed the validation of the MC program. Additionally, the algorithm for dose reporting in SimDoseCT was validated by comparing dose results from this tool with those obtained from MC simulations for three volumetric acquisitions (head, thorax and abdomen). The comparison was repeated using eight different collimations and also for another collimation in a helical abdomen examination. The results showed differences of 0.1 mSv or less for absolute dose in most organs and also in the effective dose calculation. The software provides a suitable tool for dose assessment in standard adult patients undergoing CT

Curcumin inhibits growth potential by G1 cell cycle arrest and induces apoptosis in p53-mutated COLO 320DM human colon adenocarcinoma cells.

Science.gov (United States)

Dasiram, Jade Dhananjay; Ganesan, Ramamoorthi; Kannan, Janani; Kotteeswaran, Venkatesan; Sivalingam, Nageswaran

2017-02-01

Curcumin, a natural polyphenolic compound and it is isolated from the rhizome of Curcuma longa, have been reported to possess anticancer effect against stage I and II colon cancer. However, the effect of curcumin on colon cancer at Dukes' type C metastatic stage III remains still unclear. In the present study, we have investigated the anticancer effects of curcumin on p53 mutated COLO 320DM human colon adenocarcinoma cells derived from Dukes' type C metastatic stage. The cellular viability and proliferation were assessed by trypan blue exclusion assay and MTT assay, respectively. The cytotoxicity effect was examined by lactate dehydrogenase (LDH) cytotoxicity assay. Apoptosis was analyzed by DNA fragmentation analysis, Hoechst and propidium iodide double fluorescent staining and confocal microscopy analysis. Cell cycle distribution was performed by flow cytometry analysis. Here we have observed that curcumin treatment significantly inhibited the cellular viability and proliferation potential of p53 mutated COLO 320DM cells in a dose- and time-dependent manner. In addition, curcumin treatment showed no cytotoxic effects to the COLO 320DM cells. DNA fragmentation analysis, Hoechst and propidium iodide double fluorescent staining and confocal microscopy analysis revealed that curcumin treatment induced apoptosis in COLO 320DM cells. Furthermore, curcumin caused cell cycle arrest at the G1 phase, decreased the cell population in the S phase and induced apoptosis in COLO 320DM colon adenocarcinoma cells. Together, these data suggest that curcumin exerts anticancer effects and induces apoptosis in p53 mutated COLO 320DM human colon adenocarcinoma cells derived from Dukes' type C metastatic stage. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Rapid nickel diffusion in cold-worked carbon steel at 320-450 °C

Science.gov (United States)

Arioka, Koji; Iijima, Yoshiaki; Miyamoto, Tomoki

2015-11-01

The diffusion coefficient of nickel in cold-worked carbon steel was determined with the diffusion couple method in the temperature range between 320 and 450 °C. Diffusion couple was prepared by electro-less nickel plating on the surface of a 20% cold-worked carbon steel. The growth in width of the interdiffusion zone was proportional to the square root of diffusion time to 12,000 h. The diffusion coefficient (DNi) of nickel in cold-worked carbon steel was determined by extrapolating the concentration-dependent interdiffusion coefficient to 0% of nickel. The temperature dependence of DNi is expressed by DNi = (4.5 + 5.7/-2.5) × 10-11 exp (-146 ± 4 kJ mol-1/RT) m2s-1. The value of DNi at 320 °C is four orders of magnitude higher than the lattice diffusion coefficient of nickel in iron. The activation energy 146 kJ mol-1 is 54% of the activation energy 270.4 kJ mol-1 for lattice diffusion of nickel in the ferromagnetic state iron.

Void fraction correlations analysis and their influence on heat transfer of helical double-pipe vertical evaporator

International Nuclear Information System (INIS)

Parrales, Arianna; Colorado, Dario; Huicochea, Armando; Díaz, Juan; Alfredo Hernández, J.

2014-01-01

Highlights: • 50 void fraction correlations were evaluated on heat transfer in vertical evaporators. • Two-phase flow model based on control volume formulation was used. • The drift flux parameter is common in all correlations with satisfactory results. - Abstract: An analysis of 50 void fraction correlations available in the literature was performed to describe two-phase flow mechanism inside two helical double-pipe vertical evaporators. The evaporators considered water as working fluid connected in countercurrent so the change of phase was carried out into the internal tube. The discretized equations of continuity, momentum and energy in each flow were coupled using an implicit step by step method. The selection of the void fraction correlations for the mathematical model was based on inclusion of some theoretical limits. The results of this analysis were compared with the experimental data in steady state for two different evaporators, obtaining good agreement in the evaporation process for only 7 void fraction correlations. The Armand and Massena correlation had a mean percentage error (MPE) of 3.08%, followed by Rouhanni and Axelsson I adquired MPE=3.16%, Chisholm and Armand obtained MPE=3.18%, Steiner as well as Rouhanni and Axelsson II with MPE=3.19%, Bestion reached MPE=3.20% and Flanigan presented MPE=3.21%. Furthermore, the experimental and simulated heat flux were acceptable (R 2 =0.939). Finally, the results showed that the drift flux parameter was important to evaluate the void fraction

Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography.

Science.gov (United States)

Bhardwaj, Anshul; Casjens, Sherwood R; Cingolani, Gino

2014-02-01

Protein fibers are widespread in nature, but only a limited number of high-resolution structures have been determined experimentally. Unlike globular proteins, fibers are usually recalcitrant to form three-dimensional crystals, preventing single-crystal X-ray diffraction analysis. In the absence of three-dimensional crystals, X-ray fiber diffraction is a powerful tool to determine the internal symmetry of a fiber, but it rarely yields atomic resolution structural information on complex protein fibers. An 85-residue-long minimal coiled-coil repeat unit (MiCRU) was previously identified in the trimeric helical core of tail needle gp26, a fibrous protein emanating from the tail apparatus of the bacteriophage P22 virion. Here, evidence is provided that an MiCRU can be inserted in frame inside the gp26 helical core to generate a rationally extended fiber (gp26-2M) which, like gp26, retains a trimeric quaternary structure in solution. The 2.7 Å resolution crystal structure of this engineered fiber, which measures ∼320 Å in length and is only 20-35 Å wide, was determined. This structure, the longest for a trimeric protein fiber to be determined to such a high resolution, reveals the architecture of 22 consecutive trimerization heptads and provides a framework to decipher the structural determinants for protein fiber assembly, stability and flexibility.

“Deceiving with the Truth”, Arte Nuevo, L. 319

Directory of Open Access Journals (Sweden)

Víctor de Lama

2011-06-01

Full Text Available The rhetorical device called “deceiving with the truth” (l. 319 et seq. described by Lope de Vega in the Arte Nuevo de hacer comedias has been misinterpreted ever since Morel Fatio confused it with another device mentioned by Lope a little earlier in the text (vv. 300-301, i. e. that of the need for a surprise ending. Later commentators such as H. Rennert and A. Castro, J. de José Prades, J. M. Rozas, F. Pedraza and J. Roso Díaz failed to interpret Lope’s verses correctly, despite the fact that G. T. Northrup (1929-1930 had already offered the keys to an appropriate interpretation. In the meantime, the procedure of “deceiving with the truth” has been unconvincingly identified in works such as La Celestina and dramatic texts of the sixteenth century. In order to confirm its long tradition, the article documents the device’s origin in Terence’s comedies and its use in the Middle Ages and in works such as Don Quixote.

RELIABILITAS DAN FEASIBILITAS PENGGUNAAN KARTU MENUJU SEHAT PERKEMBANGAN (KMS-P MOTOR MILESTONE ANAK UMUR 3-18 BULAN DI PUSKESMAS DAN POSYANDU

Directory of Open Access Journals (Sweden)

Yayah K. Husaini

2012-11-01

Full Text Available RELIABILITAS DAN FEASIBILITAS PENGGUNAAN KARTU MENUJU SEHAT PERKEMBANGAN (KMS-P MOTOR MILESTONE ANAK UMUR 3-18 BULAN DI PUSKESMAS DAN POSYANDU.Background: To monitor growth and development of a child could use the Road to the Health Card of Under Five (KMS-Balita for growth and Road to the Health Card of Motor Development (KMS-Perkembangan for development. The KMS-Perkembangan (KMS-P has been developed based on a scientific research design following the WHO-procedure for the development of a reference. In order the KMS-P could be used at Posyandu and/or at Puskesmas, it needs to be examined the reability and the feasibility in the field condition.Objectives: To examine the reliability and the feasibility of using KMS-P for children aged 3-18 months underfield condition.Methods: The study was carried out in Bogor City and Sukabumi District A total of 10 Puskesmas and 74 Pusyandu located in 19 villages were included as the study sites. The crossectional study designed was implemented, and 872 mothers and their children aged 3-18 months, 75 village cadres and 37 health providers were included as the sample studied. Data on general characteristics and motor milestones, reability and feasibility of using the KMS-P included plotting, its interpretation, and evaluating the child motor development were collected.Results: The study reveals that under field condition, 100% of health providers, 74.7% of village cadres and 77.56% mothers of the children studied could use the KMS-P property. The KMS-P has been developed simple, practicable, and action oriented.Conclusions: The reliability and feasilility of using KMS-P under field condition is highly acceptable. The prospect of KMS-P is very encouraging.Keywords: reliability, feasibility, motor milestone, motor development.

Project W-320, backup: 1000 CFM portable exhausters acceptance for beneficial use

International Nuclear Information System (INIS)

Nelson, O.D.

1998-01-01

This document is to identify the Project W-320 1000 CFM portable exhauster documentation required to be turned over from the Projects Organization to the Tank Farm Operations as part of the acceptance of the 1000 CFM portable exhausters for beneficial use

9 CFR 592.320 - Products that may bear the inspection mark.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Products that may bear the inspection... Marking Products § 592.320 Products that may bear the inspection mark. Products that are permitted to bear... products eligible to bear the inspection mark and may contain other edible ingredients. The official mark...

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: HVLP COATING EQUIPMENT, ITW AUTOMOTIVE REFINISHING, DEVILBISS FLG-631-318 HVLP SPRAY GUN

Science.gov (United States)

This report presents the results of the verification test of the DeVilbiss FLG-631-318 high-volume, low-pressure gravity-feed spray gun, hereafter referred to as the DeVilbiss FLG, which is designed for use in automotive refinishing. The test coating chosen by ITW Automotive Refi...

Leak behaviors of steam generator tube-to-tubesheet joints from room temperature to 320 °C

International Nuclear Information System (INIS)

Bahn, Chi Bum; Majumdar, Saurin; Kasza, Ken E.; Shack, William J.

2013-01-01

To address concerns about excessive leakage from throughwall cracks in nuclear reactor tube-to-tubesheet joints under accident conditions, leak rates were measured experimentally by using tube-to-collar joint specimens and nitrogen gas. Rates were dependent on differential pressure between the tube internal surface and the crevice (i.e., the tube-to-collar interface region) and on temperature. As specimen temperature was raised to 320 °C, leak rates decreased gradually due to changes in gas properties and to differential thermal expansion between the Alloy 600 tubes and the SA508 collars. The leak rates did not change even after repeated temperature excursions to 320 °C, suggesting that thermally induced creep and subsequent contact pressure relaxation is negligible below that temperature. When considering factors that could increase flow resistance, such as oxidation, or debris on top of the tubesheet, the measured leak rates in this work are considered to be conservative. The test results were further used to validate the contact pressure calculation and a leak rate model. Highlights: ► Leak rates were measured by using tube-to-collar joint specimens. ► Leak rates were dependent on differential pressure between tube internal and joint interface. ► Leak rates decreased gradually as specimen temperature was raided to 320 °C. ► Differential thermal expansion between Alloy 600 tube and SA508 collar plays a major role on the leak behavior.

7 CFR 319.56-20 - Apples and pears from Australia (including Tasmania) and New Zealand.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Apples and pears from Australia (including Tasmania... Fruits and Vegetables § 319.56-20 Apples and pears from Australia (including Tasmania) and New Zealand. Apples and pears from Australia (including Tasmania) and New Zealand may be imported only in accordance...

Project W-320, 241-C-106 sluicing HVAC calculations, Volume 4

Energy Technology Data Exchange (ETDEWEB)

Bailey, J.W.

1998-07-30

This supporting document has been prepared to make the FDNW calculations for Project W-320, readily retrievable. The report contains the following design calculations: Cooling load in pump pit 241-AY-102; Pressure relief seal loop design; Process building piping stress analysis; Exhaust skid maximum allowable leakage criteria; and Recirculation heat, N509 duct requirements.

Fractal Communication System Using Digital Signal Processing Starter Kit (DSK TMS320c6713

Directory of Open Access Journals (Sweden)

Arsyad Ramadhan Darlis

2015-12-01

Full Text Available In 1992, Wornell and Oppenheim did research on a modulation which is formed by using wavelet theory. In some other studies, proved that this modulation can survive on a few channels and has reliability in some applications. Because of this modulation using the concept of fractal, then it is called as fractalmodulation. Fractal modulation is formed by inserting information signal into fractal signals that are selffractal similary. This modulation technique has the potential to replace the OFDM (Orthogonal Frequency Division Multiplexing, which is currently used on some of the latest telecommunication technologies. The purpose of this research is to implement the fractal communication system using Digital Signal Processing Starter Kit (DSK TMS320C6713 without using AWGN and Rayleigh channel in order to obtain the ideal performance of the system. From the simulation results using MATLAB7.4. it appears that this communication system has good performance on some channels than any other communication systems. While in terms of implementation by using (DSK via TMS320C6713 Code Composer Studio (CCS, it can be concluded that thefractal communication system has a better execution time on some tests.

Streptomyces euryhalinus sp. nov., a new actinomycete isolated from a mangrove forest.

Science.gov (United States)

Biswas, Kaushik; Choudhury, Jayanta D; Mahansaria, Riddhi; Saha, Malay; Mukherjee, Joydeep

2017-06-01

A Gram-positive, aerobic, non-motile actinomycete (strain MS 3/20 T ) was isolated from the sediment of the Sundarbans mangrove forest in India. On International Streptomyces Project (ISP) medium 2, the isolate produced yellowish brown to red aerial hyphae that carried spiny-surfaced spores in a retinaculum-apertum arrangement. Whole-cell hydrolysate of the strain contained LL-diaminopimelic acid and galactose. Predominant menaquinones were MK-9(H 8 ) and MK-9(H 6 ). Diagnostic polar lipids were glycolipid, phosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine, unidentified phospholipid and unidentified amino lipid. The major fatty acids were anteiso-C 15:0 (17.53%), iso-C 16:0 (23.89%) and anteiso-C 17:0 (10.29%). The strain showed 100% 16S ribosomal RNA (rRNA) gene sequence similarity with Streptomyces variabilis NBRC 12825 T , Streptomyces erythrogriseus LMG 19406 T , Streptomyces griseoincarnatus LMG 19316 T and Streptomyces labedae NBRC 15864 T . However, strain MS 3/20 T could be distinguished from these and seven other closely related species based on low levels of DNA-DNA relatedness (27.2-53.8%), supported by the unique banding pattern obtained from random amplified polymorphic DNA-PCR amplification and the distinctive matrix-assisted laser desorption/ionization-time-of-flight/mass spectrometry (MALDI-TOF/MS) profile of whole-cell proteins acquired for strain MS 3/20 T in comparison with its phylogenetic relatives. Disparate morphological, physiological and chemotaxonomic features, principally growth in NaCl, further corroborated the distinction of strain MS 3/20 T from other phylogenetic relatives. Strain MS 3/20 T is therefore suggested to be a novel species of the genus Streptomyces, for which the name Streptomyces euryhalinus sp. nov. is proposed. The type strain is MS 3/20 T (=CICC 11032 T =DSM 103378 T ).

7 CFR 319.56-36 - Watermelon, squash, cucumber, and oriental melon from the Republic of Korea.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Watermelon, squash, cucumber, and oriental melon from... QUARANTINE NOTICES Fruits and Vegetables § 319.56-36 Watermelon, squash, cucumber, and oriental melon from the Republic of Korea. Watermelon (Citrullus lanatus), squash (Cucurbita maxima), cucumber (Cucumis...

Kinerja Modulasi BPSK Modem Software Defined Radio Pada DSK TMS320C6713

OpenAIRE

Sari, Sapriesty Nainy

2016-01-01

— Software Defined Radio (SDR) is a signal processing technology that optimizes the use of PC as a device supporting. With the application of SDR in wireless communication system so it will provide possibility and flexibility on manipulating DSP without the need of hardware changes. SDR modems are designed to take advantage of Digital Signal Processor Starter Kit (DSK) TMS320C6713 for baseband signal processing. In the implementation phase, the DSK is programmed directly using Matlab Simulink...

Tribological Behavior of Plasma-Sprayed Al2O3-20 wt.%TiO2 Coating

Science.gov (United States)

Cui, Shiyu; Miao, Qiang; Liang, Wenping; Zhang, Zhigang; Xu, Yi; Ren, Beilei

2017-05-01

Al2O3-20 wt.% TiO2 ceramic coatings were deposited on the surface of Grade D steel by plasma spraying of commercially available powders. The phases and the microstructures of the coatings were investigated by x-ray diffraction and scanning electron microscopy, respectively. The Al2O3-20 wt.% TiO2 composite coating exhibited a typical inter-lamellar structure consisting of the γ-Al2O3 and the Al2TiO5 phases. The dry sliding wear behavior of the coating was examined at 20 °C using a ball-on-disk wear tester. The plasma-sprayed coating showed a low wear rate ( 4.5 × 10-6 mm3 N-1 m-1), which was matrix ( 283.3 × 10-6 mm3 N-1 m-1), under a load of 15 N. In addition, the tribological behavior of the plasma-sprayed coating was analyzed by examining the microstructure after the wear tests. It was found that delamination of the Al2TiO5 phase was the main cause of the wear during the sliding wear tests. A suitable model was used to simulate the wear mechanism of the coating.

High Enthalpy Effects on Two Boundary Layer Disturbances in Supersonic and Hypersonic Flow

Science.gov (United States)

2012-05-01

of damping rate per wavelength require a degeneracy of seven ( red ). . . . . . . . . . 78 5.3 Chemical damping processes examples...diameter, over the boundary layer displacement thickness versus the Reynolds number based on element diameter, ReD = UDν . Figure 2.5: This plot shows...3.22) Substituting these relationships into Equations 3.18 and 3.19, we have (ıωIji + Aji ) fi = Aji ( ρ0ω 2g ∂q∗i ∂p ∣∣∣∣ p0 − ρ0 ∂2g ∂x2 ∂q∗i ∂ρ

Characterization and Trypanocidal Activity of a Novel Pyranaphthoquinone

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Elen Diana Dantas

2017-09-01

Full Text Available Chagas disease is an endemic parasitic infection that occurs in 21 Latin American countries. New therapies for this disease are urgently needed, as the only two drugs available (nifurtimox and benznidazol have high toxicity and variable efficacy in the disease’s chronic phase. Recently, a new chemical entity (NCE named Pyranaphthoquinone (IVS320 was synthesized from lawsone. We report herein, a detailed study of the physicochemical properties and in vitro trypanocidal activity of IVS320. A series of assays were performed for characterization, where thermal, diffractometric, and morphological analysis were performed. In addition, the solubility, permeability, and hygroscopicity of IVS320 were determined. The results show that its poor solubility and low permeability may be due to its high degree of crystallinity (99.19%, which might require the use of proper techniques to increase the IVS320’s aqueous solubility and permeability. The trypanocidal activity study demonstrated that IVS320 is more potent than the reference drug benznidazole, with IC50/24 h of 1.49 ± 0.1 μM, which indicates that IVS320 has potential as a new drug candidate for the treatment of Chagas disease.

Low Temperature (320 deg C and 340 deg C) Creep Crack Growth in Low Alloy Reactor Pressure Vessel Steel

International Nuclear Information System (INIS)

Rui Wu; Sandstroem, Rolf; Seitisleam, Facredin

2004-02-01

Uni-axial creep and creep crack growth (CCG) tests at 320 deg C and 340 deg C as well as post test metallography have been carried out in a low alloy reactor pressure vessel steel (ASTM A508 class 2) having simulated coarse grained heat affected zone microstructure. The CCG behaviour is studied in terms of steady crack growth rate, creep fracture parameter C*, stress intensity factor and reference stress at given testing conditions. It has been found that CCG does occur at both tested temperatures. The lifetimes for the CCG tests are considerably shorter than those for the uni-axial creep tests. This is more pronounced at longer lifetimes or lower stresses. Increasing temperature from 320 deg C to 340 deg C causes a reduction of lifetime by approximately a factor of five and a corresponding increase of steady crack growth rate. For the CCG tests, there are three regions when the crack length is plotted against time. After incubation, the crack grows steadily until it accelerates when rupture is approached. Notable crack growth takes place at later stage of the tests. No creep cavitation is observed and transgranular fracture is dominant for the uni-axial creep specimens. In the CT specimens the cracks propagate intergranularly, independent of temperature and time. Some relations between time to failure, reference stress and steady crack growth rate are found for the CCG tests. A linear extrapolation based on the stress-time results indicates that the reference stress causing failure due to CCG at a given lifetime of 350,000 hours at 320 deg C is clearly lower than both yield and tensile strengths, on which the design stress may have based. Therefore, caution must be taken to prevent premature failure due to low temperature CCG. Both uni-axial and CCG tests on real welded joint at 320 deg C, study of creep damage zone at crack tip as well as numerical simulation are recommended for future work

Irradiation Microstructure of Austenitic Steels and Cast Steels Irradiated in the BOR-60 Reactor at 320°C

Science.gov (United States)

Yang, Yong; Chen, Yiren; Huang, Yina; Allen, Todd; Rao, Appajosula

Reactor internal components are subjected to neutron irradiation in light water reactors, and with the aging of nuclear power plants around the world, irradiation-induced material degradations are of concern for reactor internals. Irradiation-induced defects resulting from displacement damage are critical for understanding degradation in structural materials. In the present work, microstructural changes due to irradiation in austenitic stainless steels and cast steels were characterized using transmission electron microscopy. The specimens were irradiated in the BOR-60 reactor, a fast breeder reactor, up to 40 dpa at 320°C. The dose rate was approximately 9.4x10-7 dpa/s. Void swelling and irradiation defects were analyzed for these specimens. A high density of faulted loops dominated the irradiated-altered microstructures. Along with previous TEM results, a dose dependence of the defect structure was established at 320°C.

A Sarkar

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. A Sarkar. Articles written in Bulletin of Materials Science. Volume 23 Issue 4 August 2000 pp 319-324 Polymers. An experimental investigation of electrical conductivities in biopolymers · H Mallick A Sarkar · More Details Abstract Fulltext PDF. Gum arabica obtained from acacia ...

One Dimensional Backstripping Results from IODP Expedition 318, Site U1356: Tectonic Implications for the Wilkes Land Margin of Antarctica

Science.gov (United States)

Hayden, T. G.; Kominz, M. A.; González, J. J.; Escutia, C.; Brinkhuis, H.; Scientific Party of IODP Expedition 318

2011-12-01

The Wilkes Land margin of Antarctica is the conjugate margin of the Great Australian Bight, which underwent extension, thinning and rifting from ~160 Ma until breakup at ~83 Ma. Both Wilkes Land and the Great Australian Bight are considered passive margins, and were thought to be tectonically inactive since breakup at 83 Ma. We have backstripped the U1356 Core recovered from the continental rise off Wilkes Land, Antarctica by IODP Expedition 318. Backstripping input included lithological and sedimentary analysis, paleo-environmental indicators, combined paleomagnetic and biostratigraphic chronologies, and physical properties measurements. Tectonic subsidence shows a major event between 50 and 33.6 Ma, a time represented by a hiatus in the U1356 core. The magnitude of subsidence requires it to be tectonic in origin, and the timing matches with a reorganization of plate motions that represents the transition from slow spreading to fast spreading between Antarctica and Australia, which occurred at approximately 43 Ma. Coupled with a regional seismic framework, and using other Expedition 318 site analyses, the Wilkes Land margin is shown to be far more complex then the simple passive margin currently assumed. We explore several possible mechanisms for the subsidence and erosion observed; including thermal uplift due to continental insulation of the asthenosphere and it's interaction with a recently rifted margin, asthenospheric convection, transtensional or transpressional basin development and loading, and edge-driven asthenospheric convection.

Allele frequencies of hemojuvelin gene (HJV I222N and G320V missense mutations in white and African American subjects from the general Alabama population

Directory of Open Access Journals (Sweden)

Bohannon Sean B

2004-12-01

Full Text Available Abstract Background Homozygosity or compound heterozygosity for coding region mutations of the hemojuvelin gene (HJV in whites is a cause of early age-of-onset iron overload (juvenile hemochromatosis, and of hemochromatosis phenotypes in some young or middle-aged adults. HJV coding region mutations have also been identified recently in African American primary iron overload and control subjects. Primary iron overload unexplained by typical hemochromatosis-associated HFE genotypes is common in white and black adults in Alabama, and HJV I222N and G320V were detected in a white Alabama juvenile hemochromatosis index patient. Thus, we estimated the frequency of the HJV missense mutations I222N and G320V in adult whites and African Americans from Alabama general population convenience samples. Methods We evaluated the genomic DNA of 241 Alabama white and 124 African American adults who reported no history of hemochromatosis or iron overload to detect HJV missense mutations I222N and G320V using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP technique. Analysis for HJV I222N was performed in 240 whites and 124 African Americans. Analysis for HJV G320V was performed in 241 whites and 118 African Americans. Results One of 240 white control subjects was heterozygous for HJV I222N; she was also heterozygous for HFE C282Y, but had normal serum iron measures and bone marrow iron stores. HJV I222N was not detected in 124 African American subjects. HJV G320V was not detected in 241 white or 118 African American subjects. Conclusions HJV I222N and G320V are probably uncommon causes or modifiers of primary iron overload in adult whites and African Americans in Alabama. Double heterozygosity for HJV I222N and HFE C282Y may not promote increased iron absorption.

SPECIFICATIONS FOR HIGH TEMPERATURE LATTICE TEST REACTOR BUILDING 318 PROJECT CAH-100

Energy Technology Data Exchange (ETDEWEB)

Vitro Engineering Company

1964-07-15

This is the specifications for the High Temperature Lattice Test Reactor Building 318 and it is divided into the following 21 divisions or chapters: (1) Excavating, Backfill & Grading; (2) Reinforced Concrete; (3) Masonry; (4) Structural Steel & Miscellaneous Metal Items, Contents - Division V; (5) Plumbing, Process & Service Piping; (6) Welding; (7) Insulated Metal Siding; (8) Roof Decks & Roofing; (9) Plaster Partitions & Ceiling; (10) Standard Doors, Windows & Hardware; (11) Shielding Doors; (12) Sprinkler System & Fire Extinguishers, Contents - Division XIII; (13) Heating, Ventilating & Air Conditioning; (14) Painting, Protective Coating & Floor Covering, Contents - Division XV; (15) Electrical; (16) Communications & Alarm Systems; (17) Special Equipment & Furnishings; (18) Overhead Bridge Crane; (19) Prefabricated Steel Building; (20) Paved Drive; and (21) Landscaping & Irrigation Sprinklers.

Model of nuclear reactor type VVER-1000/V-320 built by computer code ATHLET-CD

International Nuclear Information System (INIS)

Georgiev, Yoto; Filipov, Kalin; Velev, Vladimir

2014-01-01

A model of nuclear reactor type VVER-1000 V-320 developed for computer code ATHLET-CD2.1A is presented. Validation of the has been made, in the analysis of the station blackout scenario with LOCA on fourth cold leg is shown. As the calculation has been completed, the results are checked through comparison with the results from the computer codes ATHLET-2.1A, ASTEC-2.1 and RELAP5mod3.2

Identification of four novel XPC mutations in two xeroderma pigmentosum complementation group C patients and functional study of XPC Q320X mutant.

Science.gov (United States)

Gu, Yajuan; Chang, Xiaodan; Dai, Shan; Song, Qinghua; Zhao, Hongshan; Lei, Pengcheng

2017-09-10

Xeroderma pigmentosum (XP) is a rare, recessive hereditary disease characterized by sunlight hypersensitivity and high incidence of skin cancer with clinical and genetic heterogeneity. We collected two unrelated Chinese patients showing typical symptoms of XPC without neurologic symptoms. Direct sequencing of XPC gene revealed that patient 1 carried IVS1+1G>A and c.958 C>T mutations, and patient 2 carried c.545_546delTA and c.2257_2258insC mutations. All these four mutations introduced premature terminal codons (PTCs) in XPC gene. The nonsense mutation c.958 C>T yielded truncated mutant Q320X, and we studied its function for global genome repair kinetics. Overexpressed Q320X mutant can localize to site of DNA damage, but it is defective in CPD and 6-4PP repair. Readthrough of PTCs is a new approach to treatment of genetic diseases. We found that aminoglycosides could significantly increase the full length protein expression of Q320X mutant, but NER defects were not rescued in vitro. Copyright © 2017 Elsevier B.V. All rights reserved.

An L319F mutation in transmembrane region 3 (TM3) selectively reduces sensitivity to okaramine B of the Bombyx mori l-glutamate-gated chloride channel.

Science.gov (United States)

Furutani, Shogo; Okuhara, Daiki; Hashimoto, Anju; Ihara, Makoto; Kai, Kenji; Hayashi, Hideo; Sattelle, David B; Matsuda, Kazuhiko

2017-10-01

Okaramines produced by Penicillium simplicissimum AK-40 activate l-glutamate-gated chloride channels (GluCls) and thus paralyze insects. However, the okaramine binding site on insect GluCls is poorly understood. Sequence alignment shows that the equivalent of residue Leucine319 of the okaramine B sensitive Bombyx mori (B. mori) GluCl is a phenylalanine in the okaramine B insensitive B. mori γ-aminobutyric acid-gated chloride channel of the same species. This residue is located in the third transmembrane (TM3) region, a location which in a nematode GluCl is close to the ivermectin binding site. The B. mori GluCl containing the L319F mutation retained its sensitivity to l-glutamate, but responses to ivermectin were reduced and those to okaramine B were completely blocked.

Whole-brain 320-detector row dynamic volume CT perfusion detected crossed cerebellar diaschisis after spontaneous intracerebral hemorrhage

Energy Technology Data Exchange (ETDEWEB)

Fu, Jun; Chen, Wei-jian; Wang, Mei-hao; Li, Jian-ce; Zhang, Qian; Xia, Neng-zhi; Yang, Yun-jun [Wenzhou Medical University, Department of Radiology, First Affiliated Hospital, Wenzhou (China); Wu, Gui-yun [Cleveland Clinics Foundation, Department of Nuclear Medicine, Imaging Institute, Cleveland, OH (United States); Cheng, Jing-liang; Zhang, Yong [Zhengzhou University, Department of Radiology, First Affiliated Hospital, Zhengzhou (China); Zhuge, Qichuan [Wenzhou Medical University, Department of Neurosurgery, First Affiliated Hospital, Wenzhou (China)

2014-11-09

The purpose of this study was to evaluate the value of 320-detector row CT used to detect crossed cerebellar diaschisis (CCD) in patients with unilateral supratentorial spontaneous intracerebral hemorrhage (SICH). We investigated 62 of 156 patients with unilateral supratentorial SICH using 320-detector row CT scanning. Regional cerebral blood flow (rCBF), cerebral blood volume (rCBV), mean transit time (rMTT), and time to peak (rTTP) levels were measured in different regions of interest (ROIs) that were manually outlined on computed tomography perfusion (CTP) for the cerebrum, including normal-appearing brain tissue that surrounded the perilesional low-density area (NA) and the perihematomal low-density area (PA) in all patients and the cerebellum (ipsilateral and contralateral) in CCD-positive patients. Of 62 cases, a total of 14 met the criteria for CCD due to cerebellar perfusion asymmetry on CTP maps. In the quantitative analysis, significant differences were found in the perfusion parameters between the contralateral and ipsilateral cerebellum in CCD-positive cases. No significant differences were found between the CCD-positive group and the CCD-negative group according to the hematoma volume, NIHSS scores, and cerebral perfusion abnormality (each P > 0.05). The correlation analysis of the degree of NA, PA perfusion abnormality, and the degree of CCD severity showed negative and significant linear correlations (R, -0.66∝-0.56; P < 0.05). 320-detector row CT is a robust and practicable method for the comprehensive primary imaging work-up of CCD in unilateral supratentorial SICH patients. (orig.)

Whole-brain 320-detector row dynamic volume CT perfusion detected crossed cerebellar diaschisis after spontaneous intracerebral hemorrhage

International Nuclear Information System (INIS)

Fu, Jun; Chen, Wei-jian; Wang, Mei-hao; Li, Jian-ce; Zhang, Qian; Xia, Neng-zhi; Yang, Yun-jun; Wu, Gui-yun; Cheng, Jing-liang; Zhang, Yong; Zhuge, Qichuan

2015-01-01

The purpose of this study was to evaluate the value of 320-detector row CT used to detect crossed cerebellar diaschisis (CCD) in patients with unilateral supratentorial spontaneous intracerebral hemorrhage (SICH). We investigated 62 of 156 patients with unilateral supratentorial SICH using 320-detector row CT scanning. Regional cerebral blood flow (rCBF), cerebral blood volume (rCBV), mean transit time (rMTT), and time to peak (rTTP) levels were measured in different regions of interest (ROIs) that were manually outlined on computed tomography perfusion (CTP) for the cerebrum, including normal-appearing brain tissue that surrounded the perilesional low-density area (NA) and the perihematomal low-density area (PA) in all patients and the cerebellum (ipsilateral and contralateral) in CCD-positive patients. Of 62 cases, a total of 14 met the criteria for CCD due to cerebellar perfusion asymmetry on CTP maps. In the quantitative analysis, significant differences were found in the perfusion parameters between the contralateral and ipsilateral cerebellum in CCD-positive cases. No significant differences were found between the CCD-positive group and the CCD-negative group according to the hematoma volume, NIHSS scores, and cerebral perfusion abnormality (each P > 0.05). The correlation analysis of the degree of NA, PA perfusion abnormality, and the degree of CCD severity showed negative and significant linear correlations (R, -0.66∝-0.56; P < 0.05). 320-detector row CT is a robust and practicable method for the comprehensive primary imaging work-up of CCD in unilateral supratentorial SICH patients. (orig.)

Perfusion CT of the Brain and Liver and of Lung Tumors: Use of Monte Carlo Simulation for Patient Dose Estimation for Examinations With a Cone-Beam 320-MDCT Scanner.

Science.gov (United States)

Cros, Maria; Geleijns, Jacob; Joemai, Raoul M S; Salvadó, Marçal

2016-01-01

The purpose of this study was to estimate the patient dose from perfusion CT examinations of the brain, lung tumors, and the liver on a cone-beam 320-MDCT scanner using a Monte Carlo simulation and the recommendations of the International Commission on Radiological Protection (ICRP). A Monte Carlo simulation based on the Electron Gamma Shower Version 4 package code was used to calculate organ doses and the effective dose in the reference computational phantoms for an adult man and adult woman as published by the ICRP. Three perfusion CT acquisition protocols--brain, lung tumor, and liver perfusion--were evaluated. Additionally, dose assessments were performed for the skin and for the eye lens. Conversion factors were obtained to estimate effective doses and organ doses from the volume CT dose index and dose-length product. The sex-averaged effective doses were approximately 4 mSv for perfusion CT of the brain and were between 23 and 26 mSv for the perfusion CT body protocols. The eye lens dose from the brain perfusion CT examination was approximately 153 mGy. The sex-averaged peak entrance skin dose (ESD) was 255 mGy for the brain perfusion CT studies, 157 mGy for the lung tumor perfusion CT studies, and 172 mGy for the liver perfusion CT studies. The perfusion CT protocols for imaging the brain, lung tumors, and the liver performed on a 320-MDCT scanner yielded patient doses that are safely below the threshold doses for deterministic effects. The eye lens dose, peak ESD, and effective doses can be estimated for other clinical perfusion CT examinations from the conversion factors that were derived in this study.

Juvenil hæmokromatose forårsaget af homozygot Gly320Val-mutation på hæmojuvelingenet

DEFF Research Database (Denmark)

Berg, Line Brunemark; Milman, Nils Thorm; Friis-Hansen, Lennart

2013-01-01

Juvenile haemochromatosis caused by a homozygous Gly320Val mutation in the haemojuvelin (HJV) gene was diagnosed in a 12-year-old Danish girl and her 10-year-old sister. Both appeared healthy without clinical or biochemical signs of organ damage. They had iron overload (plasma transferrin saturat...

Clean Water Act Section 319 Nonpoint Source Pollution Control Projects Grants, US EPA Region 9, 2008, California Nonpoint Source Program

Data.gov (United States)

U.S. Environmental Protection Agency — The California Nonpoint Source (NPS) Program allocates about $4.5 million of CWA Section 319 funding from the U.S. Environmental Protection Agency annually to...

A Prospective Longitudinal Assessment of Medical Records for Diagnostic Substitution among Subjects Diagnosed with a Pervasive Developmental Disorder in the United States

Directory of Open Access Journals (Sweden)

David eGeier

2015-10-01

Full Text Available Background: Previously, investigators suggested that diagnostic substitution from other diagnoses, e.g., mental retardation (MR and/or cerebral palsy (CP to pervasive developmental disorder (PDD is a driving factor behind increases in PDD. This study evaluated potential diagnostic substitution among subjects diagnosed with PDD vs MR or CP by examining birth characteristic overlap.Methods: SAS® and StatsDirect software examined medical records for subjects within the Vaccine Safety Datalink (VSD database who were Health Maintenance Organization (HMO-enrolled from birth until diagnosed with an International Classification of Disease, 9th revision (ICD-9 outcome of PDD (299.xx, n=84, CP (343.xx, n=300, or MR (317.xx, 318.xx, or 319.xx, n=51.Results: Subjects with PDD had significantly (p<0.01 increased: male/female ratio (PDD=5.5 vs CP=1.5 or MR=1.3, mean age of initial diagnosis in years (PDD=3.13 vs CP=1.09 or MR=1.62, mean gestational age in weeks at birth (PDD=38.73 vs CP=36.20 or MR=34.84, mean birth weight in grams (PDD=3,368 vs CP=2,767 or MR=2,406, and mean Appearance-Pulse-Grimace-Activity-Respiration (APGAR scores at 1 minute (PDD=7.82 vs CP=6.37 or MR=6.76 and 5 minutes (PDD=8.77 vs CP=7.92 or MR=8.04, as compared to subjects diagnosed with CP or MR.Conclusion: This study suggests diagnostic substitution cannot fully explain increased PDD prevalence during the 1990s within the United States.