"Don Quijote de la Mancha," Miguel de Cervantes Saavedra. Performance Guides to Spanish Texts.

Science.gov (United States)

Gies, David Thatcher, Comp.

This performance guide is the result of work conducted at the University of Virginia's National Endowment for the Humanities Summer Institute, in 1989, on "Spanish Literature in Performance," in which 25 secondary school Spanish teachers studied Spanish texts from the perspective of classroom performance to deepen knowledge of the texts…

Expression of wheat high molecular weight glutenin subunit 1Bx is affected by large insertions and deletions located in the upstream flanking sequences.

Directory of Open Access Journals (Sweden)

Yuke Geng

Full Text Available To better understand the transcriptional regulation of high molecular weight glutenin subunit (HMW-GS expression, we isolated four Glu-1Bx promoters from six wheat cultivars exhibiting diverse protein expression levels. The activities of the diverse Glu-1Bx promoters were tested and compared with β-glucuronidase (GUS reporter fusions. Although all the full-length Glu-1Bx promoters showed endosperm-specific activities, the strongest GUS activity was observed with the 1Bx7OE promoter in both transient expression assays and stable transgenic rice lines. A 43 bp insertion in the 1Bx7OE promoter, which is absent in the 1Bx7 promoter, led to enhanced expression. Analysis of promoter deletion constructs confirmed that a 185 bp MITE (miniature inverted-repeat transposable element in the 1Bx14 promoter had a weak positive effect on Glu-1Bx expression, and a 54 bp deletion in the 1Bx13 promoter reduced endosperm-specific activity. To investigate the effect of the 43 bp insertion in the 1Bx7OE promoter, a functional marker was developed to screen 505 Chinese varieties and 160 European varieties, and only 1Bx7-type varieties harboring the 43 bp insertion in their promoters showed similar overexpression patterns. Hence, the 1Bx7OE promoter should be important tool in crop genetic engineering as well as in molecular assisted breeding.

Automatic Definition Extraction and Crossword Generation From Spanish News Text

Directory of Open Access Journals (Sweden)

Jennifer Esteche

2017-08-01

Full Text Available This paper describes the design and implementation of a system that takes Spanish texts and generates crosswords (board and definitions in a fully automatic way using definitions extracted from those texts. Our solution divides the problem in two parts: a definition extraction module that applies pattern matching implemented in Python, and a crossword generation module that uses a greedy strategy implemented in Prolog. The system achieves 73% precision and builds crosswords similar to those built by humans.

Biosynthesis and chemical transformation of benzoxazinoids in rye during seed germination and the identification of a rye Bx6-like gene

DEFF Research Database (Denmark)

Tanwir, Fariha; Dionisio, Giuseppe; B. Adhikari, Khem

2017-01-01

Benzoxazinoids are secondary metabolites with plant defense properties and possible health-promoting effects in humans. In this study, the transcriptional activity of ScBx genes (ScBx1-ScBx5; ScBx6-like), involved in benzoxazinoid biosynthesis, was analyzed during germination and early seedling...... development in rye. Our results showed that ScBx genes had highest levels of expression at 24–30 h after germination, followed by a decrease at later stages. For ScBx1-ScBx5 genes expression was higher in shoots compared with root tissues and vice versa for ScBx6-like gene transcripts. Moreover, methylated...

Vapor space characterization of waste tank 241-BX-104: Results from samples collected on 12/30/94

International Nuclear Information System (INIS)

Pool, K.H.; Ligotke, M.W.; McVeety, B.D.

1995-10-01

This report describes inorganic and organic analyses results from samples obtained from the headspace of the Hanford waste storage Tank 241-BX-104 (referred to as Tank BX-104). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained. for the inorganic compounds ammonia (NH 3 ), nitrogen dioxide (NO 2 ), nitric oxide (NO), and water (H 2 O). Sampling for hydrogen cyanide (HCN) and sulfur oxides (SOx) was not requested. In addition, quantitative results were obtained for the 39 TO-14 compounds plus an additional 14 analytes. Of these, 13 were observed above the 5-ppbv reporting cutoff. Sixty-six organic tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv and are reported with concentrations that are semiquantitative estimates based on internal-standard response factors. The 10 organic analytes, with the highest estimated concentrations are listed in Table 1 and account for approximately 70% of the total organic components in Tank BX-104. Two permanent gases, carbon dioxide (CO 2 ) and nitrous oxide (N 2 O), were also detected

Tank characterization report for Single-Shell Tank 241-BX-107

International Nuclear Information System (INIS)

Raphael, G.F.

1994-09-01

This study examined and assessed the status, safety issues, composition, and distribution of the wastes contained in the tank 241-BX-107. Historical and most recent information, ranging from engineering structural assessment experiments, process history, monitoring and remediation activities, to analytical core sample data, were compiled and interpreted in an effort to develop a realistic, contemporary profile for the tank BX-107 contents. The results of this is study revealed that tank BX-107, a 2,006,050 L (530,000 gal) cylindrical single-shell, dished-bottom carbon-steel tank in the 200 East Area of the Hanford Site, was classified as sound. It has been interim stabilized and thus contains less than 189,250 L (50,000 gal) of interstitial liquid, and less than 18,925 L (5,000 gal) of supernatant. It has also been partially interim isolated, whereby all inlets to the tank are sealed to prevent inadvertent addition of liquid. At a residual waste level of ∼3.07 m (120.7 ± 2 in. from sidewall bottom or ∼132.9 in. from center bottom), it is estimated that the tank BX-107 contents are equivalent to 1,305,825 L (345,000 gal). The vapor space pressure is at atmospheric. The latest temperature readings, which were taken in July 1994, show a moderate temperature value of 19 degrees C (66 degrees F). Two supernatant samples were collected in 1974 and 1990, prior to interim stabilization. Sludge core samples were obtained in 1979 and 1992

76 FR 53503 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2011-08-26

... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65175; File No. SR-BX-2011-057] Self-Regulatory... Establish and Adopt Fees for the New BX Pre-Trade Risk Management Service August 19, 2011. Pursuant to... 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule...

El idioma espanol en el mundo (The Spanish Language in the World)

Science.gov (United States)

Baron Castro, Rodolfo

1975-01-01

This report to the Office of Ibero-American Education concerns the status of Spanish in five areas: 1) A program on Spanish in the Philippines; 2) Spanish in the United States; 3) Cooperation with the Commission on Spanish of UNESCO; 4) A professorship in Bogota, and 5) Spanish scientific terminology. (Text is in Spanish.) (CHK)

Atmospheric dayglow diagnostics involving the O2(b-X) Atmospheric band emission: Global Oxygen and Temperature (GOAT) mapping

Science.gov (United States)

Slanger, T. G.; Pejaković, D. A.; Kostko, O.; Matsiev, D.; Kalogerakis, K. S.

2017-03-01

The terrestrial dayglow displays prominent emission features from the 0-0 and 1-1 bands of the O2 Atmospheric band system in the 760-780 nm region. We present an analysis of observations in this wavelength region recorded by the Space Shuttle during the Arizona Airglow Experiment. A major conclusion is that the dominant product of O(1D) + O2 energy transfer is O2(b, v = 1), a result that corroborates our previous laboratory studies. Moreover, critical to the interpretation of dayglow is the possible interference by N2 and N2+ bands in the 760-780 nm region, where the single-most important component is the N2 1PG 3-1 band that overlaps with the O2(b-X) 0-0 band. When present, this background must be accounted for to reveal the O2(b-X) 0-0 and 1-1 bands for altitudes at which the O2 and N2/N2+ emissions coincide. Finally, we exploit the very different collisional behavior of the two lowest O2(b) vibrational levels to outline a remote sensing technique that provides information on Atmospheric composition and temperature from space-based observations of the 0-0 and 1-1 O2 atmospheric bands.

Bilingual Text4Walking Food Service Employee Intervention Pilot Study.

Science.gov (United States)

Buchholz, Susan Weber; Ingram, Diana; Wilbur, JoEllen; Fogg, Louis; Sandi, Giselle; Moss, Angela; Ocampo, Edith V

2016-06-01

Half of all adults in the United States do not meet the level of recommended aerobic physical activity. Physical activity interventions are now being conducted in the workplace. Accessible technology, in the form of widespread usage of cell phones and text messaging, is available for promoting physical activity. The purposes of this study, which was conducted in the workplace, were to determine (1) the feasibility of implementing a bilingual 12-week Text4Walking intervention and (2) the effect of the Text4Walking intervention on change in physical activity and health status in a food service employee population. Before conducting the study reported here, the Text4Walking research team developed a database of motivational physical activity text messages in English. Because Hispanic or Latino adults compose one-quarter of all adults employed in the food service industry, the Text4Walking team translated the physical activity text messages into Spanish. This pilot study was guided by the Physical Activity Health Promotion Framework and used a 1-group 12-week pre- and posttest design with food service employees who self-reported as being sedentary. The aim of the study was to increase the number of daily steps over the baseline by 3000 steps. Three physical activity text messages were delivered weekly. In addition, participants received 3 motivational calls during the study. SPSS version 19.0 and R 3.0 were used to perform the data analysis. There were 33 employees who participated in the study (57.6% female), with a mean age of 43.7 years (SD 8.4). The study included 11 Hispanic or Latino participants, 8 of whom requested that the study be delivered in Spanish. There was a 100% retention rate in the study. At baseline, the participants walked 102 (SD 138) minutes/day (per self-report). This rate increased significantly (P=.008) to 182 (SD 219) minutes/day over the course of the study. The participants had a baseline mean of 10,416 (SD 5097) steps, which also increased

Tank characterization report for single-shell tank 241-BX-107

International Nuclear Information System (INIS)

Raphael, G.F.

1996-01-01

This study examined and assessed the status, safety issues, composition, and distribution of the wastes contained in the tank 241-BX-107. Historical and most recent information, ranging from engineering structural assessment experiments, process history, monitoring and remediation activities, to analytical core sample data, were compiled and interpreted in an effort to develop a realistic, contemporary profile for the tank BX-107 contents

78 FR 50126 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of a Proposed Rule Change To...

Science.gov (United States)

2013-08-16

.... However, as the Commission has made clear with respect to BX's affiliate, the NASDAQ Stock Exchange LLC...: Manipulation patterns that monitor solely BX activity, including patterns that monitor activity that might... the opposite side of the BX market at an improved price (often referred to as ``odd lot manipulation...

Hanford Tanks 241-AY-102 and 241-BX-101: Sludge Composition and Contaminant Release Data

International Nuclear Information System (INIS)

Krupka, Kenneth M.; Deutsch, William J.; Lindberg, Michael J.; Cantrell, Kirk J.; Hess, Nancy J.; Schaef, Herbert T.; Arey, Bruce W.

2004-01-01

This report describes the results of testing sludge samples from Hanford tanks 241-AY-102 (AY-102) and 241-BX-101 (BX-101). These tests were conducted to characterize the sludge and assess the water leachability of contaminants from the solids. This work is being conducted to support the tank closure risk assessments being performed by CH2M HILL Hanford Group, Inc. for the U.S. Department of Energy. This is the first report of testing of BX-101 sludge and the second report of testing of AY-102. Lindberg and Deutsch (2003) described the first phase of testing on AY-102 material

Heme oxygenase-1 regulates the progression of K/BxN serum transfer arthritis.

Directory of Open Access Journals (Sweden)

Rita Brines

Full Text Available Heme oxygenase-1 (HO-1 is induced in many cell types as a defense mechanism against stress. We have investigated the possible role of endogenous HO-1 in the effector phase of arthritis using the K/BxN serum transfer model of arthritis in HO-1 heterozygous and homozygous knock-out mice.Arthritis was induced in C57/Black-6 xFVB (HO-1(+/+, HO-1(+/- and HO-1(-/- mice by intraperitoneal injection of 150 µl serum from arthritic K/BxN mice at days 0 and 2. Blood was collected and animals were sacrificed at day 10. Histological analysis was performed in ankle sections. The levels of inflammatory mediators were measured in serum and paw homogenates by enzyme-linked immunosorbent assay or Multiplex technology. The incidence of arthritis was higher in HO-1(+/- and HO-1(-/- groups compared with HO-1(+/+. The inflammatory response was aggravated in HO-1(+/- mice as shown by arthritic score and the migration of inflammatory cells that could be related to the enhancement of CXCL-1 production. In addition, the HO-1(+/- group showed proteoglycan depletion significantly higher than HO-1(+/+ mice. Serum levels of matrix metalloproteinase-3, monocyte chemotactic protein-1, plasminogen activator inhibitor-1, E-selectin and intercellular adhesion molecule-1 were increased in arthritic HO-1(-/- mice, whereas vascular endothelial growth factor and some cytokines such as interferon-γ showed a reduction compared to HO-1(+/+ or HO-1(+/- mice. In addition, down-regulated gene expression of ferritin, glutathione S-reductase A1 and superoxide dismutase-2 was observed in the livers of arthritic HO-1(+/- animals.Endogenous HO-1 regulates the production of systemic and local inflammatory mediators and plays a protective role in K/BxN serum transfer arthritis.

The Sightline to Q2343-BX415: Clues to Galaxy Formation in a Quasar Environment

Science.gov (United States)

Rix, Samantha A.; Pettini, Max; Steidel, Charles C.; Reddy, Naveen A.; Adelberger, Kurt L.; Erb, Dawn K.; Shapley, Alice E.

2007-11-01

We have discovered a strong DLA coincident in redshift with the faint QSO Q2343-BX415 (R=20.2, zem=2.57393). Follow-up observations at intermediate spectral resolution reveal that the metal lines associated with this proximate DLA (PDLA) consist of two sets of absorption components. One set is moving toward the quasar with velocities of ~150-600 km s-1 this gas is highly ionized and does not fully cover the continuum source, suggesting that it is physically close to the active nucleus. The other, which accounts for most of the neutral gas, is blueshifted relative to the QSO, with the strongest component at ~-160 km s-1. We consider the possibility that the PDLA arises in the outflowing interstellar medium of the host galaxy of Q2343-BX415, an interpretation supported by strong C IV and N V absorption at nearby velocities, and by the intense radiation field longward of the Lyman limit implied by the high C II*/H I ratio. If Q2343-BX415 is the main source of these UV photons, then the PDLA is located at either ~8 or ~37 kpc from the active nucleus. Alternatively, the absorber may be a foreground star-forming galaxy unrelated to the quasar and coincidentally at the same redshift, but our deep imaging and follow-up spectroscopy of the field of Q2343-BX415 has not yet produced a likely candidate. We measure the abundances of 14 elements in the PDLA, finding an overall metallicity of ~1/5 solar and a normal pattern of relative element abundances for this metallicity. Thus, in this PDLA there is no evidence for the supersolar metallicities that have been claimed for some proximate, high-ionization, systems. Based on data obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and NASA, and was made possible by the generous financial support of the W. M. Keck Foundation.

Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells.

Science.gov (United States)

Chen, Ru-Yi; Xu, Bin; Chen, Su-Feng; Chen, Si-Si; Zhang, Ting; Ren, Jun; Xu, Jian

2014-10-28

To investigate the effect of oridonin on nuclear transcription factors and to study the relationship between biological behavior and inflammatory factors in human pancreatic cancer (BxPC-3) cells. BxPC-3 cells were treated with various concentrations of oridonin, and viability curves were generated to test for inhibitory effects of the drug on cells. The expression of cytokines such as interleukin-1β (IL-1β), IL-6, or IL-33 was detected in BxPC-3 cell supernatants using an enzyme-linked immunosorbent assay (ELISA), and the protein expression of nuclear transcription factors including nuclear factor κB, activating protein-1, signal transducer and activator of transcription 3, bone morphogenetic protein 2, transforming growth factor β1 and sma and mad homologues in BxPC-3 cells was detected using Western blot. Carcinoma hallmark-related proteins such as survivin, vascular endothelial growth factor, and matrix metallopeptidase 2 were also detected using immunoblotting, and intra-nuclear IL-33 expression was detected using immunofluorescent staining. Treatment with oridonin reduced the viability of BxPC-3 cells in a dose dependent manner. The cells exhibited reduced growth following treatment with 8 μg/mL oridonin (13.05% ± 3.21%, P hallmarks and regulated the expression of various nuclear transcription factors. The results obtained suggest that oridonin alters the hallmarks of pancreatic cancer cells through the regulation of nuclear transcription factors.

Final report for tank 241-BX-104 push mode core 126 and 127

International Nuclear Information System (INIS)

Hu, T.A.

1996-01-01

This is the final sample analysis report for tank 241-BX-104 (BX-104), cores 126 and 127. Two segments from each core yielded a total of 11 samples which were analyzed. The data quality objectives (DQOs) applicable to this sampling event were the Safety Screening DQO (Dukelow et al. 1995) and the Organic Safety DQO (Turner et al. 1995). The samples were received, extruded and analyzed at PNNL 325 Analytical Chemistry Laboratory (ACL). The analyses were performed in accordance with the Sample Analysis Plan (Gretsinger 1996) and indicated that the tank is safe with respect to the criteria in the Safety Screening and Organic DQO. Detailed analytical results were described in the analytical laboratory 45-day Report (Attachment 1, WHC-SD-WM-DP-171, REV. 0) and final report (Attachment 2, PNL-BX-104 REV.1) prepared by PNNL, 325 Laboratory. Corrections and/or exceptions to the PNNL final report are provided

Mechanical properties of hybrid organic-inorganic CH3NH3BX3 (B = Sn, Pb; X = Br, I perovskites for solar cell absorbers

Directory of Open Access Journals (Sweden)

Jing Feng

2014-08-01

Full Text Available The crystal structures, elastic and anisotropic properties of CH3NH3BX3 (B = Sn, Pb; X = Br, I compounds as solar cell absorber layers are investigated by the first-principles calculations. The type and strength of chemical bond B-X are found to determine the elastic properties. B-X bonds and the organic cations are therefore crucial to the functionalities of such absorbers. The bulk, shear, Young's modulus ranges from 12 to 30 GPa, 3 to 12 GPa, and 15 to 37 GPa, respectively. Moreover, the interaction among organic and inorganic ions would have negligible effect for elastic properties. The B/G and Poisson's ratio show it would have a good ductile ability for extensive deformation as a flexible/stretchable layer on the polymer substrate. The main reason is attributed to the low shear modulus of such perovskites. The anisotropic indices AU, AB AG, A1, A2, and A3 show ABX3 perovskite have very strong anisotropy derived from the elastic constants, chemical bonds, and symmetry.

Final report for tank 241-BX-109, push mode cores 84 and 85

International Nuclear Information System (INIS)

Schreiber, R.D.

1996-01-01

This document summarizes the sampling activities for tank 241-BX-109. This report contains tables of the analytical results on total organic compounds and total inorganic compounds in the radioactive wastes. Tank 241-BX-109 has not been on a Watch List

Enzymatic degradation of aliphatic nitriles by Rhodococcus rhodochrous BX2, a versatile nitrile-degrading bacterium.

Science.gov (United States)

Fang, Shumei; An, Xuejiao; Liu, Hongyuan; Cheng, Yi; Hou, Ning; Feng, Lu; Huang, Xinning; Li, Chunyan

2015-06-01

Nitriles are common environmental pollutants, and their removal has attracted increasing attention. Microbial degradation is considered to be the most acceptable method for removal. In this work, we investigated the biodegradation of three aliphatic nitriles (acetonitrile, acrylonitrile and crotononitrile) by Rhodococcus rhodochrous BX2 and the expression of their corresponding metabolic enzymes. This organism can utilize all three aliphatic nitriles as sole carbon and nitrogen sources, resulting in the complete degradation of these compounds. The degradation kinetics were described using a first-order model. The degradation efficiency was ranked according to t1/2 as follows: acetonitrile>trans-crotononitrile>acrylonitrile>cis-crotononitrile. Only ammonia accumulated following the three nitriles degradation, while amides and carboxylic acids were transient and disappeared by the end of the assay. mRNA expression and enzyme activity indicated that the tested aliphatic nitriles were degraded via both the inducible NHase/amidase and the constitutive nitrilase pathways, with the former most likely preferred. Copyright © 2015 Elsevier Ltd. All rights reserved.

Understanding iconic texts from Spanish - literature course in pre - university

Directory of Open Access Journals (Sweden)

Marialina Ana García Escobio

2014-09-01

Full Text Available It is presented in this article the development of the skills to understand better, which is one of the essential objectives of the teaching of the mother tongue, that is why to understand the image as iconic sign requires taking its value as a system of meaning, but also to sustain their particular difference in front of the purely denotative structures, especially against the model of all semiotic: the linguistic sign in this process of understandin g is necessary to teach students to decode texts of different codes and place them in more complex communicative situations, that is why the present proposal is new; a way to understand iconic texts, from the teaching of Spanish and Literature in preuniver sity, so that the iconic communication is common for all subjects. It is also assumed the historical and cultural approach from Vigotsky and followers, and the developing didactics presented by Castellanos and others.

Limitations of the influence of English phonetics and phonology on L2 Spanish rhotics

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Michael Kevin Olsen

2016-12-01

Full Text Available This study investigates L2 Spanish rhotic production in intermediate learners of Spanish, specifically addressing the duration of the influence of L1 English rhotic articulations and a phonetic environment involving English taps on the acquisition of Spanish taps and trills that Olsen (2012 found. Results from multiple linear regressions involving thirty-five students in Spanish foreign language classes show that the effect of English rhotic articulations evident in beginners has disappeared after four semesters of Spanish study. However, results from paired samples t-tests show that these more advanced learners produced accurate taps significantly more in words containing phonetic environments that produce taps in English. This effect is taken as evidence that L1 phonetic influences have a shorter duration on L2 production than do L1 phonological influences. These results provide insights into L2 rhotic acquisition which Spanish educators and students can use to formulate reasonable pronunciation expectations.

Using web 2.0 tools in a community service program with spanish heritage speakers in the United States

Directory of Open Access Journals (Sweden)

Jennifer LEEMAN

2011-12-01

Full Text Available Normal 0 21 false false false ES X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri","sans-serif"; mso-bidi-font-family:"Times New Roman";} This article analyzes the use of the Web 2.0 in a critical community service program in which students of Spanish from a large public institution in the United States were in charge of organizing, planning and delivering a Spanish course to young heritage speakers of Spanish. After a short description of the program and its context, the article analyzes how a class blog and a wiki were implemented as communication and collaboration tools, as well as their strengths and weaknesses in helping achieve the program’s goals. Through these technologies, it was possible to enhance participant interaction and to provide opportunities for self-reflection. In addition, the blog and the wiki helped students develop their Spanish written skills and played a role in the development of other literacies. Suggestions for future service learning programs are included at the end of the article.

Analysis of historical gross gamma logging data from BX tank farm

International Nuclear Information System (INIS)

MYERS, D.A.

1999-01-01

Gross gamma ray logs, recorded from January 1975 through mid-year 1994 as part of the Single-Shell Tank Farm Dry Well Surveillance Program, have been reanalyzed for the BX tank farm to locate the presence of mobile radionuclides in the subsurface. This report presents the BX tank farm gross gamma ray data in such a way as to assist others in their study of vadose zone mechanism

Pilot evaluation of the text4baby mobile health program

Directory of Open Access Journals (Sweden)

Evans William Douglas

2012-11-01

Full Text Available Abstract Background Mobile phone technologies for health promotion and disease prevention have evolved rapidly, but few studies have tested the efficacy of mobile health in full-fledged programs. Text4baby is an example of mobile health based on behavioral theory, and it delivers text messages to traditionally underserved pregnant women and new mothers to change their health, health care beliefs, practices, and behaviors in order to improve clinical outcomes. The purpose of this pilot evaluation study is to assess the efficacy of this text messaging campaign. Methods We conducted a randomized pilot evaluation study. All participants were pregnant women first presenting for care at the Fairfax County, Virginia Health Department. We randomized participants to enroll in text4baby and receive usual health care (intervention, or continue simply to receive usual care (control. We then conducted a 24-item survey by telephone of attitudes and behaviors related to text4baby. We surveyed participants at baseline, before text4baby was delivered to the intervention group, and at follow-up at approximately 28 weeks of baby’s gestational age. Results We completed 123 baseline interviews in English and in Spanish. Overall, the sample was predominantly of Hispanic origin (79.7% with an average age of 27.6 years. We completed 90 follow-up interviews, and achieved a 73% retention rate. We used a logistic generalized estimating equation model to evaluate intervention effects on measured outcomes. We found a significant effect of text4baby intervention exposure on increased agreement with the attitude statement “I am prepared to be a new mother” (OR = 2.73, CI = 1.04, 7.18, p = 0.042 between baseline and follow-up. For those who had attained a high school education or greater, we observed a significantly higher overall agreement to attitudes against alcohol consumption during pregnancy (OR = 2.80, CI = 1.13, 6.90, p = 0.026. We also observed a

78 FR 9961 - Self-Regulatory Organizations; NASDAQ OMS BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2013-02-12

... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-68840; File No. SR-BX-2013-008] Self-Regulatory Organizations; NASDAQ OMS BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Add Routing Functionality to the NASDAQ OMX BX Equities Market February 6, 2013. Pursuant to Section 19(b)(1...

Characterization of Vadose Zone Sediment: Borehole 299-E33-45 Near BX-102 in the B-BX-BY Waste Management Area

International Nuclear Information System (INIS)

Serne, R JEFFREY.; Last, George V.; Gee, Glendon W.; Schaef, Herbert T.; Lanigan, David C.; Lindenmeier, Clark W.; Lindberg, Michael J.; Clayton, Ray E.; Legore, Virginia L.; Orr, Robert D.; Kutnyakov, Igor V.; Baum, Steven R.; Geiszler, Keith N.; Brown, Christopher F.; Valenta, Michelle M.; Vickerman, Tanya S.

2002-01-01

The goal of the Tank Farm Vadose Zone Project is to define risks from past and future single-shell tank farm activities. This report contains all the geologic, geochemical, and selected physical characterization data collected on vadose zone sediment recovered from a borehole installed northeast of tank BX-102 (borehole 299-E33-45). This report also presents data on the sediment lithologies, the vertical extent of contamination, their migration potential, and the source of the contamination in the vadose zone and perched water east of the BX Tank Farm. The near horizontally bedded, northeasterly dipping sediment likely caused horizontal flow of the migrating contaminants. At borehole 299-E33-45, there are several fine-grained lens within the H2 unit that cause horizontally spreading of percolating fluids. The 21-ft thick Plio-pleistocene fine grained silt/clay unit is also an important horizontal flow conduit as evidenced by the perched water between 227-232 ft bgs. Based on comparing the depth of penetration of contaminants and comparing the percentages that are water leachable, uranium migrates slower than technetium-99 and nitrate. The technetium-99 desorption data are consistently near zero, meaning that the technetium-99 is not interacting with the sediment. In summary, the moisture content, pH, electrical conductivity, sodium, tritium, and uranium profiles do not suggest that plume has penetrated below 170 ft bgs. In general, the majority of the ratios of constituents found in the porewater in the Hanford formation sediments are closer to being from the 1951 metals waste solution that escaped tank BX-102 during a cascading accident. There may be a source of water, containing nitrate but not technetium, that is feeding the perched water zone. The deep vadose, perched and groundwater data do not present a clear picture on what might be occurring in the Pliopleistocene units

A Multi-wavelength Study of the Close M-dwarf Eclipsing Binary System BX Tri

Science.gov (United States)

Perdelwitz, V.; Czesla, S.; Robrade, J.; Schmitt, J. H. M. M.

2015-01-01

We present the first detailed X-ray study of the close dMe binary system BX Tri, whose optical variation has been continously monitored in the frame of the DWARF project (Pribulla et al.(2012)). We observed BX Tri with XMM-Newton for two full orbital periods and confirm that the system is an ultra-active M-dwarf binary showing frequent flares and an X-ray luminosity close to the saturation limit. The strong magnetic activity could have influenced the angular momentum evolution of the system via magnetic braking.

Monocarboxylate transporters MCT1 and MCT4 regulate migration and invasion of pancreatic ductal adenocarcinoma cells

DEFF Research Database (Denmark)

Kong, Su Chii; Nøhr-Nielsen, Asbjørn; Zeeberg, Katrine

2016-01-01

, localization, activity, and function were explored in human PDAC cells (MIAPaCa-2, Panc-1, BxPC-3, AsPC-1) and normal human pancreatic ductal epithelial (HPDE) cells, by quantitative polymerase chain reaction, immunoblotting, immunocytochemistry, lactate flux, migration, and invasion assays. RESULTS: MCT1......, or knockdown of MCT1 or MCT4. PDAC cell migration was largely unaffected by MCT1/MCT2 inhibition or MCT1 knockdown but was reduced by 4-CIN and by MCT4 knockdown (BxPC-3). Invasion measured in Boyden chamber (BxPC-3, Panc-1) and spheroid outgrowth (BxPC-3) assays was attenuated by 4-CIN and AR-C155858...

7 CFR 51.2732 - U.S. No. 2 Spanish.

Science.gov (United States)

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2 Spanish. 51.2732 Section 51.2732... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2732 U.S. No. 2 Spanish. “U.S. No. 2 Spanish” consists of shelled Spanish type peanut kernels which may be split or broken...

High temperature dielectric properties of (BxNyOz thin films deposited using ion source assisted physical vapor deposition

Directory of Open Access Journals (Sweden)

N. Badi

2015-12-01

Full Text Available The dielectric integrity has been one of the major obstacle in bringing out capacitor devices with suitable performance characteristics at high temperatures. In this paper, BxNyOz dielectric films for high temperature capacitors solutions are investigated. The films were grown on silicon substrate by using ion source assisted physical vapor deposition technique. The as-grown films were characterized by SEM, XRD, and XPS. The capacitor structures were fabricated using BxNyOz as a dielectric and titanium as metal electrodes. The elaborated devices were subjected to electrical and thermal characterization. They exhibited low electrical loss and very good stability when subjected to high temperature for a prolonged period of time.

Teaching L2 Spanish Sociopragmatics through Concepts: A Classroom-Based Study

Science.gov (United States)

van Compernolle, Rémi A.; Gomez-Laich, Maria Pia; Weber, Ashley

2016-01-01

This study explores the teaching of second language (L2) Spanish sociopragmatics through concept-based pragmatics instruction (van Compernolle, 2014). The concepts of self-presentation, social distance, and power were the focus of a pedagogical enrichment program in 2 sections of a beginning-level Spanish class at a northeastern U.S. university.…

Tank 241-BX-104 tank characterization plan

International Nuclear Information System (INIS)

Carpenter, B.C.

1994-01-01

This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-BX-104

Isolation and Molecular Characterization of High Molecular Weight Glutenin Subunit Genes 1Bx13 and 1By16 from Hexaploid Wheat

Institute of Scientific and Technical Information of China (English)

Bin-Shuang Pang; Xue-Yong Zhang

2008-01-01

The high molecular weight glutenin subunit (HMW-GS) pair 1Bx13+1Byt6 are recognized to positively correlate with bread-making quality; however, their molecular data remain unknown. In order to reveal the mechanism by which 1By16 and 1Bx13 creates high quality, their open reading frames (ORFs) were amplified from common wheat Atlas66 and Jimai 20 using primers that were designed based on published sequences of HMW glutenin genes. The ORF of 1By16 was 2220bp, deduced into 738 amino acid residues with seven cysteines including 59 hexapeptides and 22 nanopeptides motifs. The ORF of 1Bx13 was 2385bp, deduced into 795 amino acid residues with four cysteines including 68 hexapeptides, 25 nanopeptides and six tripeptides motifs. We found that 1By16 was the largest y-type HMW glutenin gene described to date in common wheat. The 1By16 had 36 amino acid residues inserted in the central repetitive domain compared with 1By15. Expression in bacteria and western-blot tests confirmed that the sequence cloned was the ORF of HMW-GS 1By16, and that 1Bx13 was one of the largest 1Bx genes that have been described so far in common wheat, exhibiting a hexapeptide (PGQGQQ) insertion in the end of central repetitive domain compared with 1Bx7. A phylogenetic tree based on the deduced full-length amino acid sequence alignment of the published HMW-GS genes showed that the 1By16 was clustered with Glu-IB-2, and that the 1Bx13 was clustered with Glu-1B-1 alleles.

Airy function approach and Numerov method to study the anharmonic oscillator potentials V(x) = Ax{sup 2α} + Bx{sup 2}

Energy Technology Data Exchange (ETDEWEB)

Al Sdran, N. [King Khalid University, Faculty of Science, Physics Department P.O. Box 9004 Abha (Saudi Arabia); Najran University, Faculty of Sciences and Arts, Najran (Saudi Arabia); Maiz, F., E-mail: fethimaiz@gmail.com [King Khalid University, Faculty of Science, Physics Department P.O. Box 9004 Abha (Saudi Arabia); Thermal Process Laboratory Research and Technologies Centre of Energy, BP 95, 2050 Hammam-lif (Tunisia)

2016-06-15

The numerical solutions of the time independent Schrödinger equation of different one-dimensional potentials forms are sometime achieved by the asymptotic iteration method. Its importance appears, for example, on its efficiency to describe vibrational system in quantum mechanics. In this paper, the Airy function approach and the Numerov method have been used and presented to study the oscillator anharmonic potential V(x) = Ax{sup 2α} + Bx{sup 2}, (A>0, B<0), with (α = 2) for quadratic, (α =3) for sextic and (α =4) for octic anharmonic oscillators. The Airy function approach is based on the replacement of the real potential V(x) by a piecewise-linear potential v(x), while, the Numerov method is based on the discretization of the wave function on the x-axis. The first energies levels have been calculated and the wave functions for the sextic system have been evaluated. These specific values are unlimited by the magnitude of A, B and α. It’s found that the obtained results are in good agreement with the previous results obtained by the asymptotic iteration method for α =3.

Shared Features of L2 Writing: Intergroup Homogeneity and Text Classification

Science.gov (United States)

Crossley, Scott A.; McNamara, Danielle S.

2011-01-01

This study investigates intergroup homogeneity within high intermediate and advanced L2 writers of English from Czech, Finnish, German, and Spanish first language backgrounds. A variety of linguistic features related to lexical sophistication, syntactic complexity, and cohesion were used to compare texts written by L1 speakers of English to L2…

Validation of the VERITAS-Pro treatment adherence scale in a Spanish sample population with hemophilia

Directory of Open Access Journals (Sweden)

Cuesta-Barriuso R

2017-03-01

Full Text Available Rubén Cuesta-Barriuso,1–3 Ana Torres-Ortuño,4 Pilar Galindo-Piñana,4 Joaquín Nieto-Munuera,4 Natalie Duncan,5 José Antonio López-Pina6 1Department of Physiotherapy, School of Biomedical and Health Sciences, European University of Madrid, 2Fishemo, Centro Especial de Empleo, Spanish Federation of Hemophilia, 3Royal Foundation Victoria Eugenia, Madrid, 4Department of Psychiatry and Social Psychology, Faculty of Medicine, University of Murcia, Murcia, Spain; 5Indiana Hemophilia & Thrombosis Center, Indianapolis, IN, USA; 6Department of Basic Psychology and Methodology, Faculty of Psychology, University of Murcia, Murcia, Spain Purpose: We aimed to conduct a validation in Spanish of the Validated Hemophilia Regimen Treatment Adherence Scale – Prophylaxis (VERITAS-Pro questionnaire for use in patients with hemophilia under prophylactic treatment.Patients and methods: The VERITAS-Pro scale was adapted through a process of back translation from English to Spanish. A bilingual native Spanish translator translated the scale from English to Spanish. Subsequently, a bilingual native English translator translated the scale from Spanish to English. The disagreements were resolved by agreement between the research team and translators. Seventy-three patients with hemophilia, aged 13–62 years, were enrolled in the study. The scale was applied twice (2 months apart to evaluate the test–retest reliability.Results: Internal consistency reliability was lower on the Spanish VERITAS-Pro than on the English version. Test–retest reliability was high, ranging from 0.83 to 0.92. No significant differences (P>0.05 were found between test and retest scores in subscales of VERITAS-Pro. In general, Spanish patients showed higher rates of nonadherence than American patients in all subscales.Conclusion: The Spanish version of the VERITAS-Pro has high levels of consistency and empirical validity. This scale can be administered to assess the degree of

77 FR 61458 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2012-10-09

... exchange to provide fair procedures for the disciplining of members and persons associated with members. Specifically, BX believes that the proposal will promote the settlement of disciplinary cases by allowing... protracted disciplinary proceeding. BX further believes that affording members with the opportunity to pay a...

Sources of SO{sub 2}, SO{sub 4}{sup 2-}, NO{sub x} and NO{sub 3}{sup -} in the air of four Spanish remote stations

Energy Technology Data Exchange (ETDEWEB)

Rua, A.; Hernandez, E.; Parras, J. de las; Martin, I.; Gimeno, L. [Complutense University, Madrid (Spain). Dept. of Statistic and Operative Investigation II

1998-09-01

In this study we have analyzed the sources of SO{sub 2}, SO{sub 4}{sup 2-}, NO{sub x}, and NO{sub 3}{sup -} in the air of four remote Spanish stations belonging to the European Monitoring and Evaluation Programme (EMEP) network. Information about trajectories has been used together with the conditional probability functions (CPFs). The most remarkable result is that the Mediterranean area is the main source of these pollutants in the air of the Spanish EMEP stations. Northern Africa and Central Europe are also important sources while the Atlantic Ocean and British Islands are, in general terms, low sources of these pollutants. The role of the Iberian Peninsula as a source of these pollutants in one of the stations, Logrono, is analyzed with more details using smaller regions to define CPFs. 26 refs., 12 figs., 2 tabs.

Glycosylphosphatidylinositol Anchor Modification Machinery Deficiency Is Responsible for the Formation of Pro-Prion Protein (PrP) in BxPC-3 Protein and Increases Cancer Cell Motility*

Science.gov (United States)

Yang, Liheng; Gao, Zhenxing; Hu, Lipeng; Wu, Guiru; Yang, Xiaowen; Zhang, Lihua; Zhu, Ying; Wong, Boon-Seng; Xin, Wei; Sy, Man-Sun; Li, Chaoyang

2016-01-01

The normal cellular prion protein (PrP) is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein. However, in pancreatic ductal adenocarcinoma cell lines, such as BxPC-3, PrP exists as a pro-PrP retaining its glycosylphosphatidylinositol (GPI) peptide signaling sequence. Here, we report the identification of another pancreatic ductal adenocarcinoma cell line, AsPC-1, which expresses a mature GPI-anchored PrP. Comparison of the 24 genes involved in the GPI anchor modification pathway between AsPC-1 and BxPC-3 revealed 15 of the 24 genes, including PGAP1 and PIG-F, were down-regulated in the latter cells. We also identified six missense mutations in DPM2, PIG-C, PIG-N, and PIG-P alongside eight silent mutations. When BxPC-3 cells were fused with Chinese hamster ovary (CHO) cells, which lack endogenous PrP, pro-PrP was successfully converted into mature GPI-anchored PrP. Expression of the individual gene, such as PGAP1, PIG-F, or PIG-C, into BxPC-3 cells does not result in phosphoinositide-specific phospholipase C sensitivity of PrP. However, when PIG-F but not PIG-P is expressed in PGAP1-expressing BxPC-3 cells, PrP on the surface of the cells becomes phosphoinositide-specific phospholipase C-sensitive. Thus, low expression of PIG-F and PGAP1 is the major factor contributing to the accumulation of pro-PrP. More importantly, BxPC-3 cells expressing GPI-anchored PrP migrate much slower than BxPC-3 cells bearing pro-PrP. In addition, GPI-anchored PrP-bearing AsPC-1 cells also migrate slower than pro-PrP bearing BxPC-3 cells, although both cells express filamin A. “Knocking out” PRNP in BxPC-3 cell drastically reduces its migration. Collectively, these results show that multiple gene irregularity in BxPC-3 cells is responsible for the formation of pro-PrP, and binding of pro-PrP to filamin A contributes to enhanced tumor cell motility. PMID:26683373

Investigation on the neutral and anionic BxAlyH2 (x + y = 7, 8, 9) clusters using density functional theory combined with photoelectron spectroscopy.

Science.gov (United States)

Ding, Li-Ping; Shao, Peng; Lu, Cheng; Zhang, Fang-Hui; Ding, Lei; Yuan, Tao Li

2016-08-17

The structure and bonding nature of neutral and negatively charged BxAlyH2 (x + y = 7, 8, 9) clusters are investigated with the aid of previously published experimental photoelectron spectra combined with the present density functional theory calculations. The comparison between the experimental photoelectron spectra and theoretical simulated spectra helps to identify the ground state structures. The accuracy of the obtained ground state structures is further verified by calculating their adiabatic electron affinities and vertical detachment energies and comparing them against available experimental data. The results show that the structures of BxAlyH2 transform from three-dimensional to planar structures as the number of boron atoms increases. Moreover, boron atoms tend to bind together forming Bn units. The hydrogen atoms prefer to bind with boron atoms rather than aluminum atoms. The analyses of the molecular orbital on the ground state structures further support the abovementioned results.

75 FR 77036 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Instituting Proceedings To Determine...

Science.gov (United States)

2010-12-10

... the agreement of such companies to comply with the Exchange's corporate governance standards along... Exchange notes, the agreement of BX- listed companies to comply with the Exchange's corporate governance... or too short? Why or why not? Are the proposed corporate governance standards for the BX listing...

78 FR 34683 - Self-Regulatory Organizations; NASDAQ OMX BX Inc.; Order Instituting Proceedings To Determine...

Science.gov (United States)

2013-06-10

... VI, Section 1(e)(1) to Chapter VI to define a Directed Order as ``an order to buy or sell which has... Directed Order to buy is received on BX and BX is not quoting at the NBO, the order would be posted on the... a decade about the tendency of passive price matching behavior to degrade price competition in...

Selected ABCB1, ABCB4 and ABCC2 Polymorphisms Do Not Enhance the Risk of Drug-Induced Hepatotoxicity in a Spanish Cohort

OpenAIRE

Ulzurrun, Eugenia; Stephens, Camilla; Ruiz-Cabello, Francisco; Robles-Diaz, Mercedes; Saenz-López, Pablo; Hallal, Hacibe; Soriano, German; Roman, Eva; Fernandez, M. Carmen; Lucena, M. Isabel; Andrade, Raúl J.

2014-01-01

[Background and Aims] Flawed ABC transporter functions may contribute to increased risk of drug-induced liver injury (DILI). We aimed to analyse the influence of genetic variations in ABC transporters on the risk of DILI development and clinical presentations in a large Spanish DILI cohort. [Methods] A total of ten polymorphisms in ABCB1 (1236T>C, 2677G>T,A, 3435T>C), ABCB4 (1954A>G) and ABCC2 (???1774G>del, ???1549A>G, ???24C>T, 1249G>A, 3972C>T and 4544G>A) were genotyped using T...

78 FR 38747 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2013-06-27

... 4120(a)(8)); A halt in a Derivative Securities Product (as defined in Rule 4120(b)(4)(A)) for which a..., 2012), 77 FR 33498 (June 6, 2012). A trading halt in a Derivative Security Product traded pursuant to... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69818; File No. SR-BX-2013-041] Self-Regulatory...

Glycosylphosphatidylinositol Anchor Modification Machinery Deficiency Is Responsible for the Formation of Pro-Prion Protein (PrP) in BxPC-3 Protein and Increases Cancer Cell Motility.

Science.gov (United States)

Yang, Liheng; Gao, Zhenxing; Hu, Lipeng; Wu, Guiru; Yang, Xiaowen; Zhang, Lihua; Zhu, Ying; Wong, Boon-Seng; Xin, Wei; Sy, Man-Sun; Li, Chaoyang

2016-02-19

The normal cellular prion protein (PrP) is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein. However, in pancreatic ductal adenocarcinoma cell lines, such as BxPC-3, PrP exists as a pro-PrP retaining its glycosylphosphatidylinositol (GPI) peptide signaling sequence. Here, we report the identification of another pancreatic ductal adenocarcinoma cell line, AsPC-1, which expresses a mature GPI-anchored PrP. Comparison of the 24 genes involved in the GPI anchor modification pathway between AsPC-1 and BxPC-3 revealed 15 of the 24 genes, including PGAP1 and PIG-F, were down-regulated in the latter cells. We also identified six missense mutations in DPM2, PIG-C, PIG-N, and PIG-P alongside eight silent mutations. When BxPC-3 cells were fused with Chinese hamster ovary (CHO) cells, which lack endogenous PrP, pro-PrP was successfully converted into mature GPI-anchored PrP. Expression of the individual gene, such as PGAP1, PIG-F, or PIG-C, into BxPC-3 cells does not result in phosphoinositide-specific phospholipase C sensitivity of PrP. However, when PIG-F but not PIG-P is expressed in PGAP1-expressing BxPC-3 cells, PrP on the surface of the cells becomes phosphoinositide-specific phospholipase C-sensitive. Thus, low expression of PIG-F and PGAP1 is the major factor contributing to the accumulation of pro-PrP. More importantly, BxPC-3 cells expressing GPI-anchored PrP migrate much slower than BxPC-3 cells bearing pro-PrP. In addition, GPI-anchored PrP-bearing AsPC-1 cells also migrate slower than pro-PrP bearing BxPC-3 cells, although both cells express filamin A. "Knocking out" PRNP in BxPC-3 cell drastically reduces its migration. Collectively, these results show that multiple gene irregularity in BxPC-3 cells is responsible for the formation of pro-PrP, and binding of pro-PrP to filamin A contributes to enhanced tumor cell motility. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

78 FR 9752 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2013-02-11

... Relating [sic] to Delay the Operative Date of a Rule Change to Exchange Rule 4121 February 1, 2013... of Substance of the Proposed Rule Change BX is filing with the Commission a proposal to delay the... delay period contained in Rule 19b-4(f)(6)(iii) of the Act \\3\\ to the extent needed for timely industry...

Sequence and properties of HMW subunit 1Bx20 from pasta wheat (Triticum durum) which is associated with poor end use properties.

Science.gov (United States)

Shewry, P R; Gilbert, S M; Savage, A W J; Tatham, A S; Wan, Y-F; Belton, P S; Wellner, N; D'Ovidio, R; Békés, F; Halford, N G

2003-02-01

The gene encoding high-molecular-weight (HMW) subunit 1Bx20 was isolated from durum wheat cv. Lira. It encodes a mature protein of 774 amino acid residues with an M(r) of 83,913. Comparison with the sequence of subunit 1Bx7 showed over 96% identity, the main difference being the substitution of two cysteine residues in the N-terminal domain of subunit 1Bx7 with tyrosine residues in 1Bx20. Comparison of the structures and stabilities of the two subunits purified from wheat using Fourier-transform infra-red and circular dichroism spectroscopy showed no significant differences. However, incorporation of subunit 1Bx7 into a base flour gave increased dough strength and stability measured by Mixograph analysis, while incorporation of subunit 1Bx20 resulted in small positive or negative effects on the parameters measured. It is concluded that the different effects of the two subunits could relate to the differences in their cysteine contents, thereby affecting the cross-linking and hence properties of the glutenin polymers.

76 FR 28838 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2011-05-18

... addresses BX Rule 3011 pertaining to anti-money laundering compliance programs. In SR-FINRA-2009-039,\\3... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To... received. III. Date of Effectiveness of the Proposed Rule Change and Timing for Commission Action Because...

78 FR 34136 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2013-06-06

... these fee and rebate changes will help to attract order flow from BX Options Market Makers and Customers..., and all written communications relating to the proposed rule change between the Commission and any... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To...

Proceedings of the International Laser Science Conference (4th) Held in Atlanta, Georgia on 2-7 October 1988 (Advances in Laser Science-4)

Science.gov (United States)

1988-10-07

under near single collision conditions and therefore not at equilibria. Relative vibrational populations input for Ma2 B-X, v’ z 0-6 werL the ratio I...Facility. REFERENCES V U. J. Tomlinson, J. P. Gordon, P. W. Smith and A. E. Kaplan , Appl. Opt. 21, 2041 (1982). 2 P. W. Smith and U. J. Tomlinson...IEEE QE-20, 30 (1984). $ A. E. Kaplan , JETP Lett. 2A, 114 (1976). A. S. Kaplan , Sov. Phys. JETP 4, 896 (1977). 4 P. W. Smith, W. J. Tomlinson, P

76 FR 55445 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2011-09-07

... Change the Name of the BX Ouch BBO Feed to the BX MatchView Feed and To Modify Its Contents August 30... Feed (the ``Feed'') and to modify the contents of the Feed in two ways. The Feed provides a view of how... the dissemination of the most accurate quotations data and by clarifying its contents. \\11\\ 15 U.S.C...

Formulation of calcium dialuminate (CaO·2Al2O3 refractory cement from local bauxite

Directory of Open Access Journals (Sweden)

A.B. Tchamba

2015-06-01

Full Text Available Three types of bauxites containing aluminum hydroxide of 58.1% gibbsite and 19.3% boehmite for BX3, 95.5% of gibbsite for BX55 and 84.5% of gibbsite for BX8 were used with lime at 95% of CaO through solid state sintering in one stage to prepare a refractory clinker at 1550 °C. The powder obtained after grinding the clinker showed in the XRD curves the presence of CaO·2Al2O3 and CaO·TiO2 phases in the cement samples. The density of cement powder varied between 2.95 and 3.17 g/cm3 and the specific area of powder obtained after grinding was between 0.72 and 0.85 m2/g. The properties of hydrated cement, W/C = 0.33, after stabilization of cement components for 48 h at 105 °C were showed by XRD, DTA, DTG and SEM (C3AH6, AH3, CA2 and CaO·TiO2. The Young's modulus of the cement made varied between 35.5 and 39.4 GPa, and these Young's moduli were compared to conventional CA14M cement.

78 FR 15385 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To...

Science.gov (United States)

2013-03-11

....] Directed Order Processing. (i) When BX's disseminated price is the NBBO and the Directed Market Maker is... received in options where BX Options is not offering Directed Order processing will not be rejected... Trading Systems * * * * * [[Page 15386

77 FR 832 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2012-01-06

... Equities Market, as well as ports to receive data from the NASDAQ OMX BX Equities Market: $400 per month for each port pair, other than Multicast ITCH[supreg] data feed pairs, for which the fee is $1000 per... Waive BX Port Pair Fees for Certain Newly-Added Routable Port Pairs December 30, 2011. Pursuant to...

Characterization of Vadose Zone Sediment: Borehole 299-E33-46 Near B 110 in the B BX-BY Waste Management Area

Energy Technology Data Exchange (ETDEWEB)

Serne, R. Jeffrey; Bjornstad, Bruce N.; Gee, Glendon W.; Schaef, Herbert T.; Lanigan, David C.; mccain, r. G.; Lindenmeier, Clark W.; Orr, Robert D.; Legore, Virginia L.; Clayton, Ray E.; Lindberg, Michael J.; Kutynakov, I. V.; Baum, Steven R.; Geiszler, Keith N.; Valenta, Michelle M.; Vickerman, Tanya S.; Royack, Lisa J.

2008-09-11

This report was revised in September 2008 to remove acid-ectractable sodium data from Table 4.17. The sodium data was removed due to potential contamination introduced during the acid extraction process. The rest of the text remains unchanged from the original report issued in December 2002. The overall goal of the of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., is to define risks from past and future single-shell tank farm activities. To meet this goal, CH2M HILL Hanford Group, Inc., asked scientists from Pacific Northwest National Laboratory to perform detailed analyses on vadose zone sediment from within the B-BX-BY Waste Management Area. This report is the third in a series of three reports to present the results of these analyses. Specifically, this report contains all the geologic, geochemical, and selected physical characterization data collected on vadose zone sediment recovered from a borehole installed approximately 4.5 m (15 ft) northeast of tank B- 110 (borehole 299-E33-46).

Chatting in L2 Spanish: Interactivity, Self-Efficacy and Interpersonal Relations

Science.gov (United States)

Sanchez-Castro, Olga; Mrowa-Hopkins, Colette

2012-01-01

This study seeks to examine variations in patterns of interactivity as they are displayed in the ongoing discourse construction of high and low self-efficacy learners of Spanish in the context of computer-mediated-communication. The paper specifically focuses on the analysis of synchronous text chats of six university students of Spanish at…

75 FR 6746 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To...

Science.gov (United States)

2010-02-10

... cabinet cooling equipment, or the re-selling of cabinet space. \\4\\ NASDAQ OMX BX is implementing a Cabinet... direct access to the Exchange quoting and trading facilities. Nor does the Exchange offer any separate or... has organized its systems to minimize, to the greatest extent possible, any advantage for one customer...

Development and preliminary evaluation of a pediatric Spanish-English speech perception task.

Science.gov (United States)

Calandruccio, Lauren; Gomez, Bianca; Buss, Emily; Leibold, Lori J

2014-06-01

The purpose of this study was to develop a task to evaluate children's English and Spanish speech perception abilities in either noise or competing speech maskers. Eight bilingual Spanish-English and 8 age-matched monolingual English children (ages 4.9-16.4 years) were tested. A forced-choice, picture-pointing paradigm was selected for adaptively estimating masked speech reception thresholds. Speech stimuli were spoken by simultaneous bilingual Spanish-English talkers. The target stimuli were 30 disyllabic English and Spanish words, familiar to 5-year-olds and easily illustrated. Competing stimuli included either 2-talker English or 2-talker Spanish speech (corresponding to target language) and spectrally matched noise. For both groups of children, regardless of test language, performance was significantly worse for the 2-talker than for the noise masker condition. No difference in performance was found between bilingual and monolingual children. Bilingual children performed significantly better in English than in Spanish in competing speech. For all listening conditions, performance improved with increasing age. Results indicated that the stimuli and task were appropriate for speech recognition testing in both languages, providing a more conventional measure of speech-in-noise perception as well as a measure of complex listening. Further research is needed to determine performance for Spanish-dominant listeners and to evaluate the feasibility of implementation into routine clinical use.

Generalized Stabilities of Euler-Lagrange-Jensen (a,b-Sextic Functional Equations in Quasi-β-Normed Spaces

Directory of Open Access Journals (Sweden)

John Michael Rassias

2017-07-01

Full Text Available The aim of this paper is to investigate generalized Ulam-Hyers stabilities of the following Euler-Lagrange-Jensen-$(a,b$-sextic functional equation $$ f(ax+by+f(bx+ay+(a-b^6\\left[f\\left(\\frac{ax-by}{a-b}\\right+f\\left(\\frac{bx-ay}{b-a}\\right\\right]\\\\ = 64(ab^2\\left(a^2+b^2\\right\\left[f\\left(\\frac{x+y}{2}\\right+f\\left(\\frac{x-y}{2}\\right\\right]\\\\ +2\\left(a^2-b^2\\right\\left(a^4-b^4\\right[f(x+f(y] $$ where $a\

Dissemination of the highly expressed Bx7 glutenin subunit (Glu-B1al allele) in wheat as revealed by novel PCR markers and RP-HPLC.

Science.gov (United States)

Butow, B J; Gale, K R; Ikea, J; Juhász, A; Bedö, Z; Tamás, L; Gianibelli, M C

2004-11-01

Increased expression of the high molecular weight glutenin subunit (HMW-GS) Bx7 is associated with improved dough strength of wheat (Triticum aestivum L.) flour. Several cultivars and landraces of widely different genetic backgrounds from around the world have now been found to contain this so-called 'over-expressing' allelic form of the Bx7 subunit encoded by Glu-B1al. Using three methods of identification, SDS-PAGE, RP-HPLC and PCR marker analysis, as well as pedigree information, we have traced the distribution and source of this allele from a Uruguayan landrace, Americano 44D, in the mid-nineteenth century. Results are supported by knowledge of the movement of wheat lines with migrants. All cultivars possessing the Glu-B1al allele can be identified by the following attributes: (1) the elution of the By sub-unit peak before the Dx sub-unit peak by RP-HPLC, (2) high expression levels of Bx7 (>39% Mol% Bx), (3) a 43 bp insertion in the matrix-attachment region (MAR) upstream of the gene promoter relative to Bx7 and an 18 bp nucleotide duplication in the coding region of the gene. Evidence is presented indicating that these 18 and 43 bp sequence insertions are not causal for the high expression levels of Bx7 as they were also found to be present in a small number of hexaploid species, including Chinese Spring, and species expressing Glu-B1ak and Glu-B1a alleles. In addition, these sequence inserts were found in different isolates of the tetraploid wheat, T. turgidum, indicating that these insertion/deletion events occurred prior to hexaploidization.

Tank characterization report for single-shell tank 241-BX-111

International Nuclear Information System (INIS)

Anantatmula, R.P.

1998-01-01

This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste, stored in Tank 241-BX-111. This report supports the requirements of the Tri-Party Agreement Milestone M-44-ISB

Digital Stories: Bringing Multimodal Texts to the Spanish Writing Classroom

Science.gov (United States)

Oskoz, Ana; Elola, Idoia

2016-01-01

Despite the availability and growing use of digital story software for authoring and instructional purposes, little is known about learners' perceptions on its integration in the foreign language writing class. Following both a social semiotics approach and activity theory, this study focuses on six advanced Spanish learners' perceptions about the…

Modulation in Tl.sub.2./sub.SeO.sub.4./sub. in the temperature range 298-90 K

Czech Academy of Sciences Publication Activity Database

Fábry, Jan; Kopecký, Miloš; Kub, Jiří

2010-01-01

Roč. 83, 10-11 (2010), s. 980-984 ISSN 0141-1594 R&D Projects: GA AV ČR IAA100100915 Grant - others:FP7/2007-2013 EC(XE) 226716 Institutional research plan: CEZ:AV0Z10100520; CEZ:AV0Z10100523 Keywords : phase transitions * A2BX4 compounds * beta-K 2 SO 4 * diffraction * synchrotrone radiation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.006, year: 2010

Vapor and gas sampling of single-shell tank 241-BX-110 using the in situ vapor sampling system

International Nuclear Information System (INIS)

Lockrem, L.L.

1997-01-01

The Vapor Issue Resolution Program tasked the Vapor Team (the team) to collect representative headspace samples from Hanford Site single-shell tank (SST) 241-BX-110. This document presents sampling data resulting from the April 30, 1996 sampling of SST 241-BX-110. Analytical results will be presented in a separate report issued by Pacific Northwest National Laboratory (PNNL), which supplied and analyzed the sampling media

78 FR 62884 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving a Proposed Rule Change To...

Science.gov (United States)

2013-10-22

... review functions focused on: (1) Manipulation patterns that monitor solely BX activity, including patterns that monitor the opening and closing crosses on The NASDAQ Stock Market LLC (``NASDAQ'') and...

Determining Factors for Stress Perception Assessed with the Perceived Stress Scale (PSS-4 in Spanish and Other European Samples

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Miguel A. Vallejo

2018-01-01

Full Text Available Objective: Stress perception depends on cultural and social aspects that vary from one country to another. One of the most widely disseminated methods of assessing psychological stress is the Perceived Stress Scale (PSS-4. Therefore, in order to identify these factors and their impact on mental health, the present study compares the PSS-4 results among three European countries (Great Britain, France and Spain. This study focuses on PSS-4 results within a Spanish sample to determine: (1 normative data, reliability and validity of PSS-4 in a Spanish sample and (2 how stress perception changes depending on cultural and social factors.Methods: The data were obtained from a website representing a service of a smoking cessation program, the study represented a service that was open to all individuals. The number of participants were 37,451. They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R.Results: The PSS-4 scores could differentiate between relevant sociodemographic variables (such as sex, age, nationality, marital status, education, parental status, employment status, and income class. The PSS-4 scores showed a positive correlation with the SCL 90-R anxiety and depression scales. The normed values for interpreting the PSS-4 scores are presented. The PSS-4 showed adequate internal consistency and reliability.Conclusions: The PSS-4 is a useful instrument for assessing stress perception levels in the general population in different countries. Its internal consistency is sufficient for a 4-item scale.

Espanol avanzado para estudiantes de literatura (Advanced Spanish for Literature Students)

Science.gov (United States)

Steel, Brian

1974-01-01

Spanish foreign language teaching should aim at the following: 1) adequate reading-comprehension ability; 2) fluency in spoken and written Spanish; and 3) ability to recognize linguistic characteristics in literature, which would serve as a basis for further graduate stylistic research. (Text is in Spanish.) (Author/DS)

Validation of a Spanish language version of the pain self-perception scale in patients with fibromyalgia

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Alda M

2010-11-01

Full Text Available Abstract Background The Pain Self-Perception Scale (PSPS is a 24-item questionnaire used to assess mental defeat in chronic pain patients. The aim of this study was to develop a Spanish language version of the PSPS (PSPS-Spanish, to assess the instrument's psychometric properties in a sample of patients with fibromyalgia and to confirm a possible overlapping between mental defeat and pain catastrophizing. Methods The PSPS was translated into Spanish by three bilingual content and linguistic experts, and then back-translated into English to assess for equivalence. The final Spanish version was administered, along with the Hospital Anxiety Depression Scale (HADS, Pain Visual Analogue Scale (PVAS, Pain Catastrophizing Scale (PCS and Fibromyalgia Impact Questionnaire (FIQ, to 250 Spanish patients with fibromyalgia. Results PSPS-Spanish was found to have high internal consistency (Cronbach's α = 0.90 and the item-total r correlation coefficients ranged between 0.68 and 0.86. Principal components analysis revealed a one-factor structure which explained 61.4% of the variance. The test-retest correlation assessed with the intraclass correlation coefficient, over a 1-2 weeks interval, was 0.78. The total PSPS score was significantly correlated with all the questionnaires assessed (HADS, PVAS, PCS, and FIQ. Conclusions The Spanish version of the PSPS appears to be a valid tool in assessing mental defeat in patients with fibromyalgia. In patients with fibromyalgia and Post-Traumatic Stress Disorder (PTSD, PSPS-Spanish correlates more intensely with FIQ than in patients without PTSD. Mental defeat seems to be a psychological construct different to pain catastrophizing.

Attenuation in the translation of bilingual journalistic texts

Directory of Open Access Journals (Sweden)

Armando González Salinas

2015-12-01

Full Text Available First approach to the identification of mitigation/intensification markers in translating journalistic articles from bilingual publication in English and its translation into Spanish. There are three articles from Newsweek Magazine, a useful tool to use with translation students. The objective is the Annotated Translation of finished articles and book chapters that, after a pre-screening analysis, foster the translation of the Spanish version from written English texts. The first journalistic article with a historical theme is: The Return of Ruthless Richard – El Regreso del despiadado Ricardo (Ricardo III, used to detect the mitigation/intensification markers in both versions. Steps: 1. Sentence by sentence analysis in English, to find mitigation characteristics. 2. Review selected sentences in English with the Spanish counterpart. 3. Comparison and contrast of both versions. 4. Discuss similarities/differences to notice if the transfer of markers signals mitigation/intensification in both versions. 5. Discuss findings and write comments of translation aspects whose changes are discussed: annotated translation. Although most mitigation studies are based on oral discourse (not excluding the written text, this research considers written texts as a means and an end, in the observation and description, since original versions are unchangeable; this opens the option to edit and modify, which is promoted, before the final version elaborated between students and researchers is reached. Some comments are included as the result of what is described above.

Eventive and Stative Passives in Spanish L2 Acquisition: A Matter of Aspect

Science.gov (United States)

De Garavito, Joyce Bruhn; Valenzuela, Elena

2008-01-01

This paper reports on an empirical study that examined knowledge of eventive and stative passives in the L2 Spanish grammar of L1 speakers of English. Although the two types of passive exist in English, the difference between them is not signaled in any specific way. In Spanish, in contrast, the distinction is marked by the choice of copula: "ser"…

An insight into Twitter: a corpus based contrastive study in English and Spanish.

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Irina Argüelles Álvarez

2012-07-01

Full Text Available The aim of this paper is to study the use of Spanish and English in the micro-blogging social network Twitter from a contrastive point of view. A quantitative research methodology is applied in order firstly, to identify specific common characteristics of language, organization and content in the medium and secondly, to find eventual differences in the use of a particular language. To carry out the experiment, two corpora were constructed using language data from Twitter, one in Spanish with a total number of 4,027,746 words and another with similar characteristics in English with a total number of 4,655,992 words. From the results obtained, the conclusion is that there are a number of very general discourse and organizational features common to the two corpora under study. It is also concluded that there are some particular characteristics which differentiate the use of English and Spanish in the medium.

Mutational screening of the USH2A gene in Spanish USH patients reveals 23 novel pathogenic mutations

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Diaz-Llopis Manuel

2011-10-01

Full Text Available Abstract Background Usher Syndrome type II (USH2 is an autosomal recessive disorder, characterized by moderate to severe hearing impairment and retinitis pigmentosa (RP. Among the three genes implicated, mutations in the USH2A gene account for 74-90% of the USH2 cases. Methods To identify the genetic cause of the disease and determine the frequency of USH2A mutations in a cohort of 88 unrelated USH Spanish patients, we carried out a mutation screening of the 72 coding exons of this gene by direct sequencing. Moreover, we performed functional minigene studies for those changes that were predicted to affect splicing. Results As a result, a total of 144 DNA sequence variants were identified. Based upon previous studies, allele frequencies, segregation analysis, bioinformatics' predictions and in vitro experiments, 37 variants (23 of them novel were classified as pathogenic mutations. Conclusions This report provide a wide spectrum of USH2A mutations and clinical features, including atypical Usher syndrome phenotypes resembling Usher syndrome type I. Considering only the patients clearly diagnosed with Usher syndrome type II, and results obtained in this and previous studies, we can state that mutations in USH2A are responsible for 76.1% of USH2 disease in patients of Spanish origin.

Cultural Understanding: Spanish Level 1.

Science.gov (United States)

Scott, Reid

The teacher's attention is focused on selected elements of Spanish culture which may be taught integrally with instructional materials found in the first-year Spanish texts "Entender y Hablar", "La Familia Fernandez", and "A-LM Spanish, Level One". Items are cross-referenced for 42 cultural concepts ranging from nicknames to streets, roads, and…

Security protocol specification and verification with AnBx

DEFF Research Database (Denmark)

Bugliesi, Michele; Calzavara, Stefano; Mödersheim, Sebastian Alexander

2016-01-01

Designing distributed protocols is complex and requires actions at very different levels: from the design of an interaction flow supporting the desired application-specific guarantees to the selection of the most appropriate network-level protection mechanisms. To tame this complexity, we propose...... with a novel notion of forwarding channels, enforcing specific security guarantees from the message originator to the final recipient along a number of intermediate forwarding agents. We give a formal semantics of AnBx in terms of a state transition system expressed in the AVISPA Intermediate Format. We devise...

Dicty_cDB: AHA685 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available 4e-82 BX640615_1( BX640615 |pid:none) Homo sapiens mRNA; cDNA DKFZp686F1... 308 4e-82 AY648777_1( AY648777 |...pid:none) Danio rerio clatherin heavy chain ... 306 1e-81 protein update 2009. 4.27 PSORT psg: 0.88 gvh: 0.2

77 FR 56883 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2012-09-14

... entered. This is not to say that Customer order flow is not important, to the contrary, the Exchange... markets and pursue Customer Order which can be freely removed at no expense. Also, it is important to note... Chapter XV, Section 2(1) to amend rebates and fees for Customers, BX Options Market Makers \\3\\ and Non...

A Spanish language and culture initiative for a doctor of pharmacy curriculum.

Science.gov (United States)

VanTyle, W Kent; Kennedy, Gala; Vance, Michael A; Hancock, Bruce

2011-02-10

To implement a Spanish language and culture initiative in a doctor of pharmacy (PharmD) curriculum that would improve students' Spanish language skills and cultural competence so that graduates could provide competent pharmaceutical care to Spanish-speaking patients. Five elective courses were created and introduced to the curriculum including 2 medical Spanish courses; a medical Spanish service-learning course; a 2-week Spanish language and cultural immersion trip to Mexico; and an advanced practice pharmacy experience (APPE) at a medical care clinic serving a high percentage of Spanish-speaking patients. Advisors placed increased emphasis on encouraging pharmacy students to complete a major or minor in Spanish. Enrollment in the Spanish language courses and the cultural immersion trip has been strong. Twenty-three students have completed the APPE at a Spanish-speaking clinic. Eleven percent of 2010 Butler University pharmacy graduates completed a major or minor in Spanish compared to approximately 1% in 2004 when the initiative began. A Spanish language and culture initiative started in 2004 has resulted in increased Spanish language and cultural competence among pharmacy students and recent graduates.

The effectiveness of visual input enhancement on the noticing and L2 development of the Spanish past tense

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Shawn Loewen

2016-03-01

Full Text Available Textual manipulation is a common pedagogic tool used to emphasize specific features of a second language (L2 text, thereby facilitating noticing and, ideally, second language development. Visual input enhancement has been used to investigate the effects of highlighting specific grammatical structures in a text. The current study uses a quasi-experimental design to determine the extent to which textual manipulation increase (a learners’ perception of targeted forms and (b their knowledge of the forms. Input enhancement was used to highlight the Spanish preterit and imperfect verb forms and an eye tracker measured the frequency and duration of participants’ fixation on the targeted items. In addition, pretests and posttests of the Spanish past tense provided information about participants’ knowledge of the targeted forms. Results indicate that learners were aware of the highlighted grammatical forms in the text; however, there was no difference in the amount of attention between the enhanced and unenhanced groups. In addition, both groups improved in their knowledge of the L2 forms; however, again, there was no differential improvement between the two groups.

Spanish? What Spanish? The Search for a 'Caribbean Standard.'

Science.gov (United States)

Hollingsworth, C.

1978-01-01

Variations in lexicon, phonology, morphology, and syntax of Spanish as spoken in Venezuela, Cuba, Mexico, and Castile have led to a diversity in the types of Spanish taught in Caribbean schools. The Programa Interamericano de Linguistica y Ensenanza de Idiomas is conducting a survey which will provide authoritative standards for Spanish teachers.…

On the L2 acquisition of Spanish-subject verb inversion

NARCIS (Netherlands)

Guerra Rivera, Alexia; Coopmans, Peter; Baauw, Sergio

2015-01-01

This study explores the acquisition of Spanish subject-verb inversion in wh-questions by Dutch L2 learners. The optional or obligatory application of this rule in Spanish wh-questions depends on the argument versus adjunct status of the wh-element. In Dutch,subject-verb inversionis obligatory in

Internet-based developmental screening: a digital divide between English- and Spanish-speaking parents.

Science.gov (United States)

Hambidge, Simon J; Phibbs, Stephanie; Beck, Arne; Bergman, David Aaron

2011-10-01

Internet-based developmental screening is being implemented in pediatric practices across the United States. Little is known about the application of this technology in poor urban populations. We describe here the results of focus groups, surveys, and in-depth interviews during home visits with families served by an urban safety-net organization to address the question of whether it is possible to use Internet or e-mail communication for medical previsit engagement in a population that is majority Hispanic, of low socioeconomic status, and has many non-English-speaking families. This study included families in 4 clinics within a safety-net health care system. The study design included the use of (1) parental surveys (n = 200) of a convenience sample of parents whose children received primary care in the clinics, (2) focus groups (n = 7 groups) with parents, and (3) in-depth interviews during home visits with 4 families. We used χ(2) and multivariate analyses to compare Internet access in English- and Spanish-speaking families. Standard qualitative methods were used to code focus-group texts and identify convergent themes. In multivariate analysis, independent factors associated with computer use were English versus Spanish language (odds ratio: 3.2 [95% confidence interval: 1.4-6.9]) and education through at least high school (odds ratio: 4.7 [95% confidence interval: 2.3-9.7]). In focus groups, the concept of parental previsit work, such as developmental screening tests, was viewed favorably by all groups. However, many parents expressed reservations about doing this work by using the Internet or e-mail and stated a preference for either paper or telephone options. Many Spanish-speaking families discussed lack of access to computers and printers. In this economically disadvantaged population, language and maternal education were associated with access to the Internet. Given the potential power of previsit work to tailor well-child visits to the needs of

El Espanol como Idioma Universal (Spanish as a Universal Language)

Science.gov (United States)

Mijares, Jose

1977-01-01

A proposal to transform Spanish into a universal language because it possesses the prerequisites: it is a living language, spoken in several countries; it is a natural language; and it uses the ordinary alphabet. Details on simplification and standardization are given. (Text is in Spanish.) (AMH)

Semantic Categorization of Placement Verbs in L1 and L2 Danish and Spanish

Science.gov (United States)

Cadierno, Teresa; Ibarretxe-Antuñano, Iraide; Hijazo-Gascón, Alberto

2016-01-01

This study investigates semantic categorization of the meaning of placement verbs by Danish and Spanish native speakers and two groups of intermediate second language (L2) learners (Danish learners of L2 Spanish and Spanish learners of L2 Danish). Participants described 31 video clips picturing different types of placement events. Cluster analyses…

THE SPANISH SCIENTIFIC JOURNALS: A DESCRIPTIVE APPROACH

Directory of Open Access Journals (Sweden)

Melba G. Claudio-González

2017-02-01

Full Text Available The main objective of this article is to present a broad description of Spanish scientific journals. The results were obtained from a survey distributed to 1,280 editors of Spanish scientific journals included in Dulcinea database (2012 edition. The response rate was 43,8%. As specific objectives, the study aimed to characterize scientific journals and to analyze the particularities of a set of parameters that make up the economic, strategic and operational dimensions of the journals in the period studied. The results show that the funding model of the Spanish scientific journals depends mainly on institutional support, that many journals lack a stable organizational structure and rely heavily on volunteer work, and that the debate on the limitations and difficulties affecting the development of open access remains open.

Analysis of Dietary Pattern Impact on Weight Status for Personalised Nutrition through On-Line Advice: The Food4Me Spanish Cohort

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Rodrigo San-Cristobal

2015-11-01

Full Text Available Obesity prevalence is increasing. The management of this condition requires a detailed analysis of the global risk factors in order to develop personalised advice. This study is aimed to identify current dietary patterns and habits in Spanish population interested in personalised nutrition and investigate associations with weight status. Self-reported dietary and anthropometrical data from the Spanish participants in the Food4Me study, were used in a multidimensional exploratory analysis to define specific dietary profiles. Two opposing factors were obtained according to food groups’ intake: Factor 1 characterised by a more frequent consumption of traditionally considered unhealthy foods; and Factor 2, where the consumption of “Mediterranean diet” foods was prevalent. Factor 1 showed a direct relationship with BMI (β = 0.226; r2 = 0.259; p < 0.001, while the association with Factor 2 was inverse (β = −0.037; r2 = 0.230; p = 0.348. A total of four categories were defined (Prudent, Healthy, Western, and Compensatory through classification of the sample in higher or lower adherence to each factor and combining the possibilities. Western and Compensatory dietary patterns, which were characterized by high-density foods consumption, showed positive associations with overweight prevalence. Further analysis showed that prevention of overweight must focus on limiting the intake of known deleterious foods rather than exclusively enhance healthy products.

Response gene to complement-32 enhances metastatic phenotype by mediating transforming growth factor beta-induced epithelial-mesenchymal transition in human pancreatic cancer cell line BxPC-3

Directory of Open Access Journals (Sweden)

Zhu Liang

2012-03-01

Full Text Available Abstract Background Response gene to complement-32 (RGC-32 is comprehensively expressed in many kinds of tissues and has been reported to be expressed abnormally in different kinds of human tumors. However, the role of RGC-32 in cancer remains controversial and no reports have described the effect of RGC-32 in pancreatic cancer. The present study investigated the expression of RGC-32 in pancreatic cancer tissues and explored the role of RGC-32 in transforming growth factor-beta (TGF-β-induced epithelial-mesenchymal transition (EMT in human pancreatic cancer cell line BxPC-3. Methods Immunohistochemical staining of RGC-32 and E-cadherin was performed on specimens from 42 patients with pancreatic cancer, 12 with chronic pancreatitis and 8 with normal pancreas. To evaluate the role of RGC-32 in TGF-β-induced EMT in pancreatic cancer cells, BxPC-3 cells were treated with TGF-β1, and RGC-32 siRNA silencing and gene overexpression were performed as well. The mRNA expression and protein expression of RGC-32 and EMT markers such E-cadherin and vimentin were determined by quantitative reverse transcription-PCR (qRT-PCR and western blot respectively. Finally, migration ability of BxPC-3 cells treated with TGF-β and RGC-32 siRNA transfection was examined by transwell cell migration assay. Results We found stronger expression of RGC-32 and higher abnormal expression rate of E-cadherin in pancreatic cancer tissues than those in chronic pancreatitis tissues and normal pancreatic tissues. Immunohistochemical analysis revealed that both RGC-32 positive expression and E-cadherin abnormal expression in pancreatic cancer were correlated with lymph node metastasis and TNM staging. In addition, a significant and positive correlation was found between positive expression of RGC-32 and abnormal expression of E-cadherin. Furthermore, in vitro, we found sustained TGF-β stimuli induced EMT and up-regulated RGC-32 expression in BxPC-3 cells. By means of si

Spanish scientific output on Helicobacter pylori. A study through Medline.

Science.gov (United States)

Trapero-Marugán, M; Gisbert, J P; Pajares, J M

2006-04-01

to analyze scientific output from Spanish hospitals in relation to Helicobacter pylori infection. papers collected from the Medline database between January 1988 and December 2003 were selected. Our search strategy was: "Helicobacter pylori" [MeSH] AND ((Spain [AD] OR Espana [AD] OR Spanien [AD] OR Espagne [AD] OR Espanha [AD]) OR (Spanish [LA]) OR Spain). The following was analyzed: geographic area, Spanish or foreign publication, topic, and year of publication. Output and impact bibliometric markers were evaluated. in all, 691 papers were identified, of which 241 were excluded. Number of papers went from 2 in 1988 to 47 in 2002 and 13 in 2003. There were more reports in Spanish versus foreign journals (58 vs. 42%). In the first 5 years the areas with greater output were associated with diagnosis and microbiology (33 and 20%), whereas therapy was the predominating subject during the last 5 years (27%). Original papers were most common among publications (69%). Hospitals with highest output included La Princesa (24%) and Ramón y Cajal (17.6%) in Madrid, and Parc Taulí in Barcelona (6.4%). Mean impact factor progressively increased from 1.826 in 1988 to 2.142 in 2002 and 2.493 in 2003. the production and impact of documents published by Spanish scientists regarding H. pylori infection considerably increased during the past two decades.

Characterization of Vadose Zone Sediment: RCRA Borehole 299-E33-338 Located Near the B-BX-BY Waste Management Area

Energy Technology Data Exchange (ETDEWEB)

Lindenmeier, Clark W.; Serne, R. Jeffrey; Bjornstad, Bruce N.; Gee, Glendon W.; Schaef, Herbert T.; Lanigan, David C.; Lindberg, Michael J.; Clayton, Ray E.; Legore, Virginia L.; Kutnyakov, Igor V.; Baum, Steven R.; Geiszler, Keith N.; Brown, Christopher F.; Valenta, Michelle M.; Vickerman, Tanya S.; Royack, Lisa J.

2008-09-11

This report was revised in September 2008 to remove acid-extractable sodium data from Table 4.8. The sodium data was removed due to potential contamination introduced during the acid extraction process. The rest of the text remains unchanged from the original report issued in June 2003. The overall goals of the of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., are: 1) to define risks from past and future single-shell tank farm activities, 2) to identify and evaluate the efficacy of interim measures, and 3) to aid via collection of geotechnical information and data, future decisions that must be made by the U.S. Department of Energy (DOE) regarding the near-term operations, future waste retrieval, and final closure activities for the single-shell tank waste management areas. For a more complete discussion of the goals of the Tank Farm Vadose Zone Project, see the overall work plan, Phase 1 RCRA Facility Investigation/Corrective Measures Study Work Plan for the Single-Shell Tank Waste Management Areas (DOE 1999). Specific details on the rationale for activities performed at the B-BX-BY tank farm waste management area are found in CH2M HILL (2000).

Monosyllabic Place Holders in Child Acquisition of Spanish as a Second Language

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Estrella Nicolás

2018-03-01

Full Text Available Monosyllabic place holders (MPHs have been studied extensively in first-language (L1 acquisition of Spanish and other Romance languages. However, the study of MPHs in second-language (L2 acquisition, both by children and adults, has received much less attention. This study provides evidence for the presence of MPHs in the L2 Spanish of two L1 Moroccan Arabic children living in Spain. The age difference between the children (10;9 for Rachida and 6;10 for Khalid allows us to address the issue of whether the younger child would use MPHs, as is the case in L1 acquisition. However, what the data show is that both children used MPHs, although Khalid’s MPH rate was slightly higher than Rachida’s. Therefore, based on these findings we argue that MPHs can constitute a strategy available for all child learners of Spanish.

Factor structure and psychometric properties of a Spanish translation of the Body Appreciation Scale-2 (BAS-2).

Science.gov (United States)

Swami, Viren; García, Antonio Alías; Barron, David

2017-09-01

We examined the psychometric properties of a Spanish translation of the Body Appreciation Scale-2 (BAS-2) in a community sample of 411 women and 389 men in Almería, Spain. Participants completed the 10-item BAS-2 along with measures of appearance evaluation, body areas satisfaction, self-esteem, life satisfaction, and self-reported body mass index (BMI). Exploratory factor analyses with one split-half subsample revealed that BAS-2 scores had a one-dimensional factor structure in women and men. Confirmatory factor analysis with a second split-half subsample showed the one-dimensional factor structure had acceptable fit and was invariant across sex. There were no significant sex differences in BAS-2 scores. BAS-2 scores were significantly and positively correlated with appearance evaluation, body areas satisfaction, self-esteem, and life satisfaction. Body appreciation was significantly and negatively correlated with BMI in men, but associations in women were only significant in the second subsample. Results suggest that the Spanish BAS-2 has adequate psychometric properties. Copyright © 2017 Elsevier Ltd. All rights reserved.

Lexical Anglicisms in Spanish and Slovak: a Contrastive Study

Directory of Open Access Journals (Sweden)

Bohdan Ulašin

2015-12-01

Full Text Available This article compares two languages, Castillian Spanish and Slovak and contrasts the status and use of English loanwords in each language. It is a small part of a larger project comparing the lexical and semantic levels of both languages. The article classifies and gives examples of differences in the treatment of anglicisms between the two, starting with phonetic differences (introducing the most notable ones, orthographic, semantic and structural differences, then looking at synonyms and calques and ending with a discussion of the presence or absence of anglicisms in the cases of denotative mismatches. We also emphasize the importance of taking into account the cultural equivalent of the English loanwords in the extralinguistic reality of Spain and Slovakia. The phenomenon of so called pseudo-anglicisms in Spanish is mentioned, as well as the extremely numerous presence of false friends in Spanish (in comparison with Slovak. The article summarises the most typical differences between European Spanish and American Spanish varieties with regard to English loanwords. The article also discusses the case of acronyms, contrasting the use of English international acronyms in Slovak with the tendency to translate them in Spanish.

SMAD4 loss enables EGF, TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells.

Science.gov (United States)

Moz, Stefania; Basso, Daniela; Bozzato, Dania; Galozzi, Paola; Navaglia, Filippo; Negm, Ola H; Arrigoni, Giorgio; Zambon, Carlo-Federico; Padoan, Andrea; Tighe, Paddy; Todd, Ian; Franchin, Cinzia; Pedrazzoli, Sergio; Punzi, Leonardo; Plebani, Mario

2016-10-25

Epidermal Growth Factor (EGF) receptor overexpression, KRAS, TP53, CDKN2A and SMAD4 mutations characterize pancreatic ductal adenocarcinoma. This mutational landscape might influence cancer cells response to EGF, Transforming Growth Factor β1 (TGFβ1) and stromal inflammatory calcium binding proteins S100A8/A9. We investigated whether chronic exposure to EGF modifies in a SMAD4-dependent manner pancreatic cancer cell signalling, proliferation and invasion in response to EGF, TGFβ1 and S100A8/A9. BxPC3, homozigously deleted (HD) for SMAD4, and BxPC3-SMAD4+ cells were or not stimulated with EGF (100 ng/mL) for three days. EGF pre-treated and non pretreated cells were stimulated with a single dose of EGF (100 ng/mL), TGFβ1 (0,02 ng/mL), S100A8/A9 (10 nM). Signalling pathways (Reverse Phase Protein Array and western blot), cell migration (Matrigel) and cell proliferation (XTT) were evaluated. SMAD4 HD constitutively activated ERK and Wnt/β-catenin, while inhibiting PI3K/AKT pathways. These effects were antagonized by chronic EGF, which increased p-BAD (anti-apoptotic) in response to combined TGFβ1 and S100A8/A9 stimulation. SMAD4 HD underlied the inhibition of NF-κB and PI3K/AKT in response to TGFβ1 and S100A8/A9, which also induced cell migration. Chronic EGF exposure enhanced cell migration of both BxPC3 and BxPC3-SMAD4+, rendering the cells less sensitive to the other inflammatory stimuli. In conclusion, SMAD4 HD is associated with the constitutive activation of the ERK and Wnt/β-catenin signalling pathways, and favors the EGF-induced activation of multiple signalling pathways critical to cancer proliferation and invasion. TGFβ1 and S100A8/A9 mainly inhibit NF-κB and PI3K/AKT pathways and, when combined, sinergize with EGF in enhancing anti-apoptotic p-BAD in a SMAD4-dependent manner.

76 FR 49805 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Science.gov (United States)

2011-08-11

... examination that would be applicable to proprietary traders. The Series 56 examination program is shared by BX... training, experience and competence for members and their associated persons, in particular, by offering a...

BX in-situ oil-shale project. Quarterly technical progress report, June 1, 1981-August 31, 1981

Energy Technology Data Exchange (ETDEWEB)

Dougan, P.M.

1981-09-20

June 1, 1981-August 31, 1981 was the third consecutive quarter of superheated steam injection at the BX In Situ Oil Shale Project. Injection was continuous except for the period of July 14th to August 1st when the injection was suspended during the drilling of core hole BX-37. During the quarter, 99,760 barrels of water as superheated steam were injected into Project injection wells at an average well head temperature of 752/sup 0/F and an average wellhead pressure of 1312 PSIG. During the same period, 135,469 barrels of fluid were produced from the Project production wells for a produced to injected fluid ratio of 1.36 to 1.0. Net oil production during the quarter was 38 barrels.

Supporting document for the historical tank content estimate for BX-tank farm

International Nuclear Information System (INIS)

Brevick, C.H.

1996-01-01

This Supporting Document provides historical in-depth characterization information on BX-Tank Farm, such as historical waste transfer and level data, tank physical information,temperature plots, liquid observation well plots, chemical analyte and radionuclide inventories for the Historical Tank Content Estimate Report for the northeast quadrant of the Hanford 200 East Area

Borehole Data Package for Wells 299-E33-334 and 299-E33-335 at Single-Shell Tank Waste Management Area B-BX-BY

International Nuclear Information System (INIS)

Horton, Duane G.

2000-01-01

Two new Resource Conservation and Recovery Act (RCRA) groundwater monitoring wells were installed at the single-shell tank farm Waste Management Area (WMA) B-BX-BY during December 1999 through February 2000 in fulfillment of Tri-Party Agreement (Ecology 1996) Milestone M-24-45. The wells are 299-E33-334 and 299-E33-335. These wells were installed in support of the WMA B-BX-BY assessment to track the movement of contaminant plumes that appear to be entering the WMA from the northeast. Well 299-E33-334 is located outside the southwest corner of the 241-BX tank farm and well 299-E33-335 is located south of the 241-BX tank farm. The locations of all wells in the extended monitoring network for WMA B-BX-BY are shown on Figure 1. The new wells were constructed to the specifications and requirements described in Washington Administrative Code (WAC) 173-160 and WAC 173-303, in the assessment groundwater monitoring plan (Narbutovskih 2000), and in the description of work for well drilling and installation. This document compiles information on the drilling, construction, well development, pump installation, and sampling activities applicable to wells 299-E33-334 and 299-E33-335. Appendix A contains copies of the Well Summary Sheets (as-built diagrams), the Well Construction Summary Reports, and the geologist's logs. Appendix B contains results of laboratory analyses of moisture content on samples from 299-E33-334 (moisture data were not collected from well 299-E33-335). Appendix C contains borehole geophysical logs and Appendix D contains analytical results from groundwater samples obtained during well construction. Additional documentation concerning well construction is on file with Bechtel Hanford, Inc. English units are used in this report because that is the system of units used by drillers to measure and report depths and well construction details. Conversion to metric is made by multiplying feet by 0.3048 to obtain meters or multiplying inches by 2.54 to obtain

Interface strategies in monolingual and end-state L2 Spanish grammars are not that different

Directory of Open Access Journals (Sweden)

Maria Carmen eParafita Couto

2015-01-01

Full Text Available This study explores syntactic, pragmatic, and lexical influences on adherence to SV and VS orders in native and fluent L2 speakers of Spanish. A judgment task examined 20 native monolingual and 20 longstanding L2 bilingual Spanish speakers’ acceptance of SV and VS structures. Seventy-six distinct verbs were tested under a combination of syntactic and pragmatic constraints. Our findings challenge the hypothesis that internal interfaces are acquired more easily than external interfaces (Sorace, 2005, 2011; Sorace & Filiaci, 2006; White 2006. Additional findings are that (a bilinguals' judgments are less firm overall than monolinguals' (i.e., monolinguals are more likely to give extreme yes or no judgments and (b individual verbs do not necessarily behave as predicted under standard definitions of unaccusatives and unergatives. Correlations of the patterns found in the data with verb frequencies suggest that usage-based accounts of grammatical knowledge could help provide insight into speakers' knowledge of these constructs.

STAT4 gene influences genetic predisposition to ulcerative colitis but not Crohn's disease in the Spanish population: a replication study.

Science.gov (United States)

Diaz-Gallo, Lina Marcela; Palomino-Morales, Rogelio J; Gómez-García, María; Cardeña, Carlos; Rodrigo, Luis; Nieto, Antonio; Alcain, Guillermo; Cueto, Ignacio; López-Nevot, Miguel A; Martin, Javier

2010-05-01

Recently, the signal transducer and activator of transcription 4 (STAT4) gene has been associated with multiple autoimmune diseases. Interestingly, a recent work showed that the T allele of the rs7574865 STAT4 SNP was associated with inflammatory bowel disease (IBD) in a Spanish population. The aim of the present study was to reevaluate the role of the STAT4 rs7574865 polymorphism on IBD. The present case-control study included 498 Crohn's disease (CD) patients, 402 ulcerative colitis (UC) patients, and 1296 healthy matched controls. Genotyping was performed using a PCR system with a pre-developed TaqMan allelic discrimination assay for the rs7574865 STAT4 SNP. Moreover, a meta-analysis was performed with the previous work in a Spanish population and the current study, including a final sample size of 1574 IBD patients (820 with CD and 754 with UC) and 2012 healthy controls. No evidence of association was found for the current case-control study (CD: p = 0.23, OR = 0.9, 95% CI = 0.75-1.1; UC: p = 0.17, OR = 1.14, 95% CI = 0.95-1.38). However, the meta-analysis showed that the STAT4 rs7574865 T allele was significantly associated with susceptibility to UC (p = 0.012 pooled; OR = 1.20, 95% CI = 1.04-1.39) but not CD (p = 0.71 pooled; OR = 0.93, 95% CI = 0.65-1.34). Our data suggest that the rs7574865 STAT4 SNP is a genetic susceptibility variant for UC but not CD in the Spanish population. Copyright 2010 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

[Analysis of literature citations in original articles published in Spanish and international nursing journals and journals in 2 closely related disciplines].

Science.gov (United States)

Muñoz-Soler, Verónica; Flores-López, María José; Cabañero-Martínez, María José; Richart-Martínez, Miguel

2007-01-01

To compare Spanish nursing journals with 2 English-language standard journals, as well as Spanish journals in closely related disciplines, to identify possible quantitative and qualitative shortcomings in scientific documentation. We performed a descriptive, cross-sectional study of the references contained in 796 articles from 6 Spanish journals from 3 health disciplines (2000-2002) and 2 English-language nursing journals (2000-2001). The number of references, type of publication cited, and language of the document cited were compared in individual journals, and in journals grouped by discipline and according to language. Spanish-language nursing journals had the lowest mean number of references per article (X- = 16.20) when compared with psychology journals (X- = 31.24), medical journals (X- = 31.39) and international nursing journals (X- = 37.11). Among Spanish journals, citation of English-language publications was most frequent in medical journals (X- = 26.28) and least frequent in nursing journals (X- = 6.04). In contrast, citation of Spanish documents was most frequent in nursing journals (X- = 9.79) and least frequent in medical journals (X- = 4.43). Although scientific publication of Spanish nursing has improved, it is not comparable to publication of closely related disciplines and international nursing. The low citation of English documents clearly reveals the risk of scientific insularity.

Spectrum of ABCA4 (ABCR) gene mutations in Spanish patients with autosomal recessive macular dystrophies.

Science.gov (United States)

Paloma, E; Martínez-Mir, A; Vilageliu, L; Gonzàlez-Duarte, R; Balcells, S

2001-06-01

The ABCA4 gene has been involved in several forms of inherited macular dystrophy. In order to further characterize the complex genotype-phenotype relationships involving this gene, we have performed a mutation analysis of ABCA4 in 14 Spanish patients comprising eight STGD (Stargardt), four FFM (fundus flavimaculatus), and two CRD (Cone-rod dystrophy) patients. SSCP (single-strand conformation polymorphism) analysis and DNA sequencing of the coding and 5' upstream regions of this gene allowed the identification of 16 putatively pathogenic alterations, nine of which are novel. Most of these were missense changes, and no patient was found to carry two null alleles. Overall, the new data agree with a working model relating the different pathogenic phenotypes to the severity of the mutations. When considering the information presented here together with that of previous reports, a picture of the geographic distribution of three particular mutations emerges. The R212C change has been found in French, Italian, Dutch, German, and Spanish but not in British patients. In the Spanish collection, R212C was found in a CRD patient, indicating that it may be a rather severe change. In contrast, c.2588G>C, a very common mild allele in the Dutch population, is rarely found in Southern Europe. Interestingly, the c.2588G>C mutation has been found in a double mutant allele together with the missense R1055W. Finally, the newly described L1940P was found in two unrelated Spanish patients, and may be a moderate to severe allele. Copyright 2001 Wiley-Liss, Inc.

Tank 241-BX-104 vapor sampling and analysis tank characterization report

International Nuclear Information System (INIS)

Huckaby, J.L.

1995-01-01

This report presents the details of the Hanford waste tank characterization study for tank 241-BX-104. The drivers and objectives of the headspace vapor sampling and analysis were in accordance with procedure that were presented in other reports. The vapor and headspace gas samples were collected and analyzed to determine the potential risks to tank farm workers due to fugitive emissions from the tank

FTA Corpus: a parallel corpus of English and Spanish Free Trade Agreements for the study of specialized collocations

Directory of Open Access Journals (Sweden)

Pedro Patiño García

2013-04-01

Full Text Available This paper describes the Corpus of Free Trade Agreements (henceforth FTA, a specialized parallel corpus in English and Spanish from Europe and America and a smaller subcorpus in English-Norwegian and Spanish-Norwegian that was prepared and then aligned with Translation Corpus Aligner 2 (Hofland & Johansson, 1998. The data was taken from Free Trade Agreements. These agreements are specialized texts officially signed and ratified by several countries and blocks of countries in the last twenty years. Thus, FTAs are a rich repository for terminology and phraseology that is used in different fields of business activity throughout the world. The corpus contains around 1.37 million words in the English section and 1.48 million words in its Spanish counterpart, plus 60,000 words each in the Spanish-Norwegian and English-Norwegian subcorpus. The corpus is being used primarily to study the terms and specialized collocations that include these terms in this kind of specialized texts.Keywords: specialized collocation, specialized parallel corpus, corpus linguistics, Free Trade Agreement

Notable Books in Spanish for Children and Young Adults from Spanish-Speaking Countries.

Science.gov (United States)

Schon, Isabel

1985-01-01

Presents a bibliography of books recently published in Mexico, Spain, Argentina, and Peru for Spanish-speaking children and young adults. The books are grouped by the following levels: (1) preschool and primary grades; (2) grades 3 to 6; (3) junior high and up; and (4) young adult. (SED)

Spanish ATLAS Tier-2: facing up to LHC Run 2

CERN Document Server

Gonzalez de la Hoz, Santiago; Fassi, Farida; Fernandez Casani, Alvaro; Kaci, Mohammed; Lacort Pellicer, Victor Ruben; Montiel Gonzalez, Almudena Del Rocio; Oliver Garcia, Elena; Pacheco Pages, Andres; Sánchez, Javier; Sanchez Martinez, Victoria; Salt, José; Villaplana Perez, Miguel

2015-01-01

The goal of this work is to describe the way of addressing the main challenges of Run-2 by the Spanish ATLAS Tier-2. The considerable increase of energy and luminosity for the upcoming Run-2 with respect to Run-1 has led to a revision of the ATLAS computing model as well as some of the main ATLAS computing tools. The adaptation on these changes will be shown, with the peculiarities that it is a distributed Tier-2 composed of three sites and its members are involved on ATLAS computing tasks with a hub of research, innovation and education.

Cancer Health Literacy Test-30-Spanish (CHLT-30-DKspa), a New Spanish-Language Version of the Cancer Health Literacy Test (CHLT-30) for Spanish-Speaking Latinos.

Science.gov (United States)

Echeverri, Margarita; Anderson, David; Nápoles, Anna María

2016-01-01

This article describes the adaptation and initial validation of the Cancer Health Literacy Test (CHLT) for Spanish speakers. A cross-sectional field test of the Spanish version of the CHLT (CHLT-30-DKspa) was conducted among healthy Latinos in Louisiana. Diagonally weighted least squares was used to confirm the factor structure. Item response analysis using 2-parameter logistic estimates was used to identify questions that may require modification to avoid bias. Cronbach's alpha coefficients estimated scale internal consistency reliability. Analysis of variance was used to test for significant differences in CHLT-30-DKspa scores by gender, origin, age and education. The mean CHLT-30-DKspa score (N = 400) was 17.13 (range = 0-30, SD = 6.65). Results confirmed a unidimensional structure, χ(2)(405) = 461.55, p = .027, comparative fit index = .993, Tucker-Lewis index = .992, root mean square error of approximation = .0180. Cronbach's alpha was .88. Items Q1-High Calorie and Q15-Tumor Spread had the lowest item-scale correlations (.148 and .288, respectively) and standardized factor loadings (.152 and .302, respectively). Items Q19-Smoking Risk, Q8-Palliative Care, and Q1-High Calorie had the highest item difficulty parameters (difficulty = 1.12, 1.21, and 2.40, respectively). Results generally support the applicability of the CHLT-30-DKspa for healthy Spanish-speaking populations, with the exception of 4 items that need to be deleted or revised and further studied: Q1, Q8, Q15, and Q19.

Experiencing the body during pregnancy: A qualitative research study among Spanish sportswomen.

Science.gov (United States)

Martinez-Pascual, Beatriz; Abuín-Porras, Vanesa; Pérez-de-Heredia-Torres, Marta; Martínez-Piedrola, Rosa María; Fernández-de-las-Peñas, César; Palacios-Ceña, Domingo

2016-01-01

The aim of the current qualitative phenomenological study was to describe the body experiences during pregnancy among Spanish elite sportswomen. Twenty Spanish sportswomen with the following criteria were included: (1) aged between 18 and 65 years; (2) had been pregnant during their professional sporting career; and (3) after the end of their pregnancy, had returned to their professional sports career for at least 1 year. A qualitative thematic analysis was conducted. Data were collected from May 2010 to April 2012 using in-depth personal interviews, investigator's field notes, and extracts from the participants' personal letters. Identified themes included: (1) a new body; (2) body control; (3) to feel their bodies and communicate with them; and (4) body's beauty ideal. Understanding the meaning of the body experience for elite Spanish sportswomen might provide us with deeper insight into their expectations and might help in the development of training systems focused on them.

Tipster Text Phase 2 Architecture Design

Science.gov (United States)

1996-06-19

TIPSTER Text Phase II Architecture Design Version 2.1p 19 June 1996 Ralph Grishman New York University grishman @cs.nyu.edu and the TIPSTER...1996 2. REPORT TYPE 3. DATES COVERED 00-00-1996 to 00-00-1996 4. TITLE AND SUBTITLE TIPSTER Text Phase II Architecture Design 5a. CONTRACT

[Adaptation and validation of the SMP-T2D questionnaire in Spanish for evaluating self-management of high blood pressure and type 2 diabetes: PAG-DT2+HTA].

Science.gov (United States)

Galván Flores, G M; Gallegos Carrillo, K; Palomo Piñon, S; Sánchez García, S; Cuadros Moreno, J; Martínez Olivares, M V; Cuevas Cancino, J J; Grijalva, I; Sánchez Arenas, R

High blood pressure is one of the most common chronic conditions worldwide. It affects one in every 3 adults over 40, while one in 10 suffers from diabetes. For both diseases, adherence to pharmacological treatment is over 30%, and self-management, which takes into account diet and physical activity, is still unknown, as there is no tool available to measure self-management. Therefore, the object of this study was to adapt and validate the Spanish version of the self-management profile for type 2 diabetes (SMP-T2D) questionnaire in patients with type 2 diabetes and high blood pressure among users of first level care in the social security institution of Mexico. The SMP-T2D was adapted to Spanish by translation into Spanish, and being used only in patients with high blood pressure and type 2 diabetes-hypertension. A convergent and discriminatory validation was performed. Patients over 50 years old with high blood pressure were include. Those that did not complete the questionnaire or give informed consent were rejected. The Spanish version of the SMP-T2D was called PAG-DT2+HTA, and was applied to 145 people with hypertension: 54.4% with hypertension only, and 43.6% with hypertension and type 2 diabetes. Mean age was 66.14 years (SD=10.78), with 34.7% women and 65.3% men. Internal consistency by α-Cronbach for the questionnaire was 0.561 (P=.000). The correlation between the PAG-DT2+HTA and Morisky-Green was significant. The ability to discriminate between people with and without education and with and without economic means was obtained. The Spanish version of SMP-T2D (PAG-DT2+HTA) that measures self-management in type 2 diabetes, can be used to measure self-management in people with type 2 diabetes-hypertension. Copyright © 2017 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

Prevalence of high blood pressure and association with obesity in Spanish schoolchildren aged 4-6 years old.

Science.gov (United States)

Martín-Espinosa, Noelia; Díez-Fernández, Ana; Sánchez-López, Mairena; Rivero-Merino, Irene; Lucas-De La Cruz, Lidia; Solera-Martínez, Montserrat; Martínez-Vizcaíno, Vicente

2017-01-01

The prevalence of high blood pressure in children is increasing worldwide, largely, but not entirely, driven by the concurrent childhood obesity epidemic. The aims of this study were to examine the prevalence of prehypertension and hypertension in 4-to-6-year-old Spanish schoolchildren, and to evaluate the association between different blood pressure (BP) components with different adiposity indicators. Cross-sectional study including a sample of 1.604 schoolchildren aged 4-to-6-years belonging to 21 schools from the provinces of Ciudad Real and Cuenca, Spain. We measured height, weight, body mass index (BMI), fat mass percentage (%FM), triceps skinfold thickness (TST), waist circumference (WC), systolic and diastolic BP, mean arterial pressure and pulse pressure. The estimates of prevalence of prehypertension and hypertension were 12.3% and 18.2%, respectively. In both sexes, adiposity indicators were positively and significantly associated with all BP components (phigh blood pressure in Spanish children. Moreover, high levels of adiposity are associated with high blood pressure in early childhood, which support that it could be related to cardiovascular risk later in life.

Genetic Regulation of Hypothalamic Cocaine and Amphetamine-Regulated Transcript (CART) in BxD Inbred Mice

Science.gov (United States)

Hawks, Brian W.; Li, Wei; Garlow, Steven J.

2009-01-01

Cocaine-Amphetamine Regulated Transcript (CART) peptides are implicated in a wide range of behaviors including in the reinforcing properties of psychostimulants, feeding and energy balance and stress and anxiety responses. We conducted a complex trait analysis to examine natural variation in the regulation of CART transcript abundance (CARTta) in the hypothalamus. CART transcript abundance was measured in total hypothalamic RNA from 26 BxD recombinant inbred (RI) mouse strains and in the C57BL/6 (B6) and DBA/2J (D2) progenitor strains. The strain distribution pattern for CARTta was continuous across the RI panel, which is consistent with this being a quantitative trait. Marker regression and interval mapping revealed significant quantitative trait loci (QTL) on mouse chromosome 4 (around 58.2cM) and chromosome 11 (between 20–36cM) that influence CARTta and account for 31% of the between strain variance in this phenotype. There are numerous candidate genes and QTL in these chromosomal regions that may indicate shared genetic regulation between CART expression and other neurobiological processes referable to known actions of this neuropeptide. PMID:18199428

Subsurface Conditions Description of the B and BX and BY Waste Management Area

Energy Technology Data Exchange (ETDEWEB)

WOOD, M.I.

2000-03-13

This document provides a discussion of the subsurface conditions relevant to the occurrence and migration of contaminants in the vadose zone and groundwater underlying the 241-B, -BX, and -BY tank farms. This document provides a concise summary of existing information in support of characterization planning. This document includes a description of the available environmental contamination data and a limited, qualitative interpretation of these data.

Subsurface Conditions Description of the B and BX and BY Waste Management Area

International Nuclear Information System (INIS)

WOOD, M.I.

2000-01-01

This document provides a discussion of the subsurface conditions relevant to the occurrence and migration of contaminants in the vadose zone and groundwater underlying the 241-B, -BX, and -BY tank farms. This document provides a concise summary of existing information in support of characterization planning. This document includes a description of the available environmental contamination data and a limited, qualitative interpretation of these data

Journalistic Text Production

DEFF Research Database (Denmark)

Haugaard, Rikke Hartmann

, a multiple case study investigated three professional text producers’ practices as they unfolded in their natural setting at the Spanish newspaper, El Mundo. • Results indicate that journalists’ revisions are related to form markedly more often than to content. • Results suggest two writing phases serving...... at the Spanish newspaper, El Mundo, in Madrid. The study applied a combination of quantitative and qualitative methods, i.e. keystroke logging, participant observation and retrospective interview. Results indicate that journalists’ revisions are related to form markedly more often than to content (approx. three...

Initial Remedial Action Plan for Expanded Bioventing System BX Service Station, Patrick Air Force Base, Florida

National Research Council Canada - National Science Library

1995-01-01

This initial remedial action plan presents the scope for an expanded bioventing system for in situ treatment of fuel-contaminated soils at the BX Service Station at Patrick Air Force Base (AFB), Florida...

Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population

International Nuclear Information System (INIS)

Peña-Chilet, Maria; Ribas, Gloria; Blanquer-Maceiras, Maite; Ibarrola-Villava, Maider; Martinez-Cadenas, Conrado; Martin-Gonzalez, Manuel; Gomez-Fernandez, Cristina; Mayor, Matias; Aviles, Juan Antonio; Lluch, Ana

2013-01-01

Few high penetrance genes are known in Malignant Melanoma (MM), however, the involvement of low-penetrance genes such as MC1R, OCA2, ASIP, SLC45A2 and TYR has been observed. Lately, genome-wide association studies (GWAS) have been the ideal strategy to identify new common, low-penetrance susceptibility loci. In this case–control study, we try to validate in our population nine melanoma associated markers selected from published GWAS in melanoma predisposition. We genotyped the 9 markers corresponding to 8 genes (PARP1, MX2, ATM, CCND1, NADSYN1, CASP8, IRF4 and CYP2R1) in 566 cases and 347 controls from a Spanish population using KASPar probes. Genotypes were analyzed by logistic regression and adjusted by phenotypic characteristics. We confirm the protective role in MM of the rs3219090 located on the PARP1 gene (p-value 0.027). Additionally, this SNP was also associated with eye color (p-value 0.002). A second polymorphism, rs12203592, located on the IRF4 gene was associated with protection to develop MM for the dominant model (p-value 0.037). We have also observed an association of this SNP with both lentigines (p-value 0.014) and light eye color (p-value 3.76 × 10 -4 ). Furthermore, we detected a novel association with rs1485993, located on the CCND1 gene, and dark eye color (p-value 4.96 × 10 -4 ). Finally, rs1801516, located on the ATM gene, showed a trend towards a protective role in MM similar to the one firstly described in a GWAS study. To our knowledge, this is the first time that these SNPs have been associated with MM in a Spanish population. We confirmed the proposed role of rs3219090, located on the PARP1 gene, and rs12203592, located on the IRF4 gene, as protective to MM along the same lines as have previous genome-wide associated works. Finally, we have seen associations between IRF4, PARP1, and CCND1 and phenotypic characteristics, confirming previous results for the IRF4 gene and presenting novel data for the last two, suggesting that

Labor transitions of Spanish workers: a flexicurity approach

Directory of Open Access Journals (Sweden)

Ángel Alonso Domínguez

2013-04-01

Full Text Available This paper uses data from the Continuous Sample of Working Lives (MCVL to assess whether flexicurity can contribute to solving endemic problems in the Spanish labor market. Two different periods are considered: 2005–2007, in which the unprecedented expansion of the Spanish economy came to an end, and 2008–2010, which clearly shows how the economic crisis has affected the employment rate. The results obtained bear out the preliminary hypotheses. More specifically, a labor market transitions have come to a halt, and b contractual arrangements which may act as gateways to more stable employment are being misused.

A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis.

Directory of Open Access Journals (Sweden)

Luis M Real

Full Text Available BACKGROUND: Non-hereditary colorectal cancer (CRC is a complex disorder resulting from the combination of genetic and non-genetic factors. Genome-wide association studies (GWAS are useful for identifying such genetic susceptibility factors. However, the single loci so far associated with CRC only represent a fraction of the genetic risk for CRC development in the general population. Therefore, many other genetic risk variants alone and in combination must still remain to be discovered. The aim of this work was to search for genetic risk factors for CRC, by performing single-locus and two-locus GWAS in the Spanish population. RESULTS: A total of 801 controls and 500 CRC cases were included in the discovery GWAS dataset. 77 single nucleotide polymorphisms (SNPs from single-locus and 243 SNPs from two-locus association analyses were selected for replication in 423 additional CRC cases and 1382 controls. In the meta-analysis, one SNP, rs3987 at 4q26, reached GWAS significant p-value (p = 4.02×10(-8, and one SNP pair, rs1100508 CG and rs8111948 AA, showed a trend for two-locus association (p = 4.35×10(-11. Additionally, our GWAS confirmed the previously reported association with CRC of five SNPs located at 3q36.2 (rs10936599, 8q24 (rs10505477, 8q24.21(rs6983267, 11q13.4 (rs3824999 and 14q22.2 (rs4444235. CONCLUSIONS: Our GWAS for CRC patients from Spain confirmed some previously reported associations for CRC and yielded a novel candidate risk SNP, located at 4q26. Epistasis analyses also yielded several novel candidate susceptibility pairs that need to be validated in independent analyses.

Spanish translation Questionnaire of the Developmental Coordination Disorder

Directory of Open Access Journals (Sweden)

Salamanca LM

2012-05-01

Full Text Available The developmental coordination disorder can be recognized by motor difficulties that affect the performance in daily and school activities; therefore, it is necessary to get its early diagnosis in order to initiate early intervention. A tool for diagnosis is the Developmental coordination disorder questionnaire’07, DCDQ’07. Objective: the translation and cultural adaptation of the DCDQ’07 into Spanish. Materials and methods: three independent translators translated the questionnaire into Spanish. Its items were classified according to their equivalent or non-equivalent problems in some words, and also according to their experiential, semantic, conceptual or idioms equivalence. Results: 8 items out of 15 questionnaire items were classified as equivalent 8, 6 of them presented problems in a few words and only one was classified as non-equivalent, 10 items correspond to experiential equivalence translation, 4 items were classified as semantic equivalent and only one got two equivalents. The author agreed the Spanish version. Also, the parent´s opinions about the questionnaire were positive. Conclusions: most of the items of the questionnaire did not have translation difficulties. It allowed its translation and cultural adaptation into Spanish as well as its validation continuity and reliability process

Drafting. A Bilingual Text = Dibujo Mecanico. Un Texto Bilingue.

Science.gov (United States)

Los Angeles Unified School District, CA. Div. of Career and Continuing Education.

This bilingual instructional text, one in a series of six texts covering various vocational and technical topics, provides secondary level English and Spanish instruction in drafting. Addressed in the individual units are the following topics: safety, drafting tools and techniques, sketching, geometric construction, working drawings, sectioning,…

In vitro and in vivo anticancer efficacy of silibinin against human pancreatic cancer BxPC-3 and PANC-1 cells.

Science.gov (United States)

Nambiar, Dhanya; Prajapati, Vandana; Agarwal, Rajesh; Singh, Rana P

2013-06-28

Silibinin suppresses the growth of many cancers; however, its efficacy against pancreatic cancer has not been evaluated in established preclinical models. Here, we investigated in vitro and in vivo effects of silibinin against lower and advanced stages of human pancreatic carcinoma cells. Silibinin (25-100μM) treatment for 24-72h caused a dose- and time-dependent cell growth inhibition of 27-77% (PPANC-1 cells. Silibinin showed a strong dose-dependent G1 arrest in BxPC-3 cells (upto 72% versus 45% in control; PPANC-1 cells. Cell death observed in cell growth assay, was accompanied by up to 3-fold increase (PPANC-1 cells. Dietary feeding of silibinin (0.5%, w/w in AIN-93M diet for 7weeks) inhibited BxPC-3 and PANC-1 tumor xenografts growth in nude mice without any apparent change in body weight gain and diet consumption. Tumor volume and weight were decreased by 47% and 34% (P⩽0.001) in BxPC-3 xenograft, respectively. PANC-1 xenograft showed slower growth kinetics and silibinin decreased tumor volume by 34% (PPANC-1 xenograft showed 28% and 33% decrease in tumor volume and weight, respectively. Silibinin-fed group of BxPC-3 tumors showed decreased cell proliferation and angiogenesis and an increased apoptosis, however, considerable inhibitory effect was observed only for angiogenesis in PANC-1 tumors. Overall, these findings show both in vitro as well as in vivo anticancer efficacy of silibinin against pancreatic cancer that could involve inhibition of cell proliferation, cell cycle arrest, apoptosis induction and/or decrease in tumor angiogenesis. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Ethnicity as a determinant of ovarian reserve: differences in ovarian aging between Spanish and Indian women.

Science.gov (United States)

Iglesias, Carlos; Banker, Manish; Mahajan, Nalini; Herrero, Leyre; Meseguer, Marcos; Garcia-Velasco, Juan A

2014-07-01

To investigate differences in ovarian reserve markers (antimüllerian hormone [AMH] and antral follicle count [AFC]) in Indian and Spanish women. Cross-sectional study. In vitro fertilization (IVF) clinics. Infertile Spanish (n=229) and Indian (n=236) women who underwent controlled ovarian stimulation for IVF from January to October 2012. None. Data on ovarian reserve markers and results after ovarian stimulation were collected. The mean age of women undergoing their first or second IVF cycle was significantly higher in Spanish than in Indian women (37.5±3.3 years vs. 31.5±3.8 years). Despite this 6-year age gap, AFCs were similar (9.5±4.7 vs. 9.9±4.6), as were day 3 FSH levels (7.5±4.5 IU/L vs. 6.9±2.3 IU/L). AMH levels were slightly lower in Spanish women (1.6±1.7 ng/mL vs. 2.5±1.6 ng/mL). Multivariate regression analysis showed that being Indian decreased AFC by 2.3, such that AFC in Indian women was similar to that in Spanish women 6.3 years older (95% confidence interval 3.39-1.10). Similar ovarian reserve markers and ovarian response were observed in women with a 6-year age difference in favor of the Spanish, suggesting ethnic differences in ovarian aging. Further research is needed to understand whether these differences are genetically induced or are caused by other variables, such as nutrition. Our results may help clinicians to counsel infertile women when discussing assisted reproductive technology outcomes according to age and ethnic background. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

75 FR 34490 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving Proposed Rule Change To...

Science.gov (United States)

2010-06-17

..., there are a variety of alternative sources of information that impose significant competitive pressures..., imposed significant competitive pressure on BX to act equitably, fairly, and reasonably in setting the.... As in the Commission's NYSE Arca Order analysis, at least two broad types of significant competitive...

Las uniones conjuntivas en espanol (Conjunctive Correspondences in Spanish)

Science.gov (United States)

Perez Botero, Luis

1977-01-01

This study of the medieval Spanish concept of order examines uses made of the word "y" ("and") in Spanish medieval writing to join words and phrases connoting social, natural and human order. (Text is in Spanish.) (CHK)

Borehole data package for wells 299-E33-334 and 299-E33-335 at single-shell tank waste management Area B-BX-BY

Energy Technology Data Exchange (ETDEWEB)

DG Horton

2000-06-01

Two new Resource Conservation and Recovery Act (RCRA) groundwater monitoring wells were installed at the single-shell tank farm Waste Management Area (WMA) B-BX-BY during December 1999 through February 2000 in fulfillment of Tri-Party Agreement (Ecology 1996) Milestone M-24-45. The wells are 299-E33-334 and 299-E33-335. These wells were installed in support of the WMA B-BX-BY assessment to track the movement of contaminant plumes that appear to be entering the WMA from the northeast. Well 299-E33-334 is located outside the southwest comer of the 241-BX tank farm and well 299-E33-335 is located south of the 241-BX tank farm. The locations of all wells in the extended monitoring network for WMA B-BX-BY are shown in a figure. The new wells were constructed to the specifications and requirements described in Washington Administrative Code (WAC) 173-160 and WAC 173-303, in the assessment groundwater monitoring plan (Narbutovskih 2000), and in the description of work for well drilling and installation. This document compiles information on the drilling, construction, well development, pump installation, and sampling activities applicable to wells 299-E33-334 and 299-E33-335. Appendix A contains copies of the Well Summary Sheets (as-built diagrams), the Well Construction Summary Reports, and the geologist's logs. Appendix B contains results of laboratory analyses of moisture content on samples from 299-E33-334 (moisture data were not collected from well 299-E33-335). Appendix C contains borehole geophysical logs and Appendix D contains analytical results from groundwater samples obtained during well construction. Additional documentation concerning well construction is on file with Bechtel Hanford, Inc.

Regional Spanish Tourism Competitiveness. A DEA-MONITUR approach

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Juan Carlos Martín

2017-11-01

Full Text Available The aim of this paper is to analyse the regional tourist competitiveness performance in Spain. We use the seven pillars of tourism from a very detailed and complete database compiled by the Spanish Government –MoniTUR 2010 as primary data. Thus, we calculate a DEA-MONITUR regional tourist competitiveness index in order to compare and rank the total 17 Spanish Autonomous Communities using data envelopment analysis (DEA. Our results show how this performance is very different among regions, and the position of each of the laggard Autonomous Communities should be analysed by their respective destination management organizations (DMOs in order to envisage adequate corrective measures.

Social networks, politics and Commitment 2.0: Spanish MPs on Facebook

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José Sixto, B.A.

2011-01-01

Full Text Available In a technologically and sociologically advanced society, the organizations that do not use the new media and the cyber communication techniques are probably doomed to failure. In this virtual sphere the social networks constitute a suitable resource and channel for the implementation of political marketing 2.0, as it provides a scenario where the interaction with users is possible. From this perspective, we verified their presence of the 350 members of the Spanish Congress on Facebook, the country’s most popular social network, in order to establish the predominant typologies, updating frequency, contents, resources, and the types of information posted in this spaces.This article also examines the interactivity of MPs in what we have termed Commitment 2.0: political communication in personal contexts such as social networks requires going from the participatory attitude to the participatory action; that is, to accept the interaction 2.0 as the correct behaviour on the network.

Medical and neuropsychiatric phenomena depicted in two Spanish medieval texts of Marian miracles.

Science.gov (United States)

de Assis Aquino Gondim, Francisco; Bastante, Pamela; Gondim, Wilcar Cavalcante; Filha, Joana Gurgel Holanda; Thomas, Florian P

2018-03-01

In the history of Christianity, veneration of the Virgin Mary reached its greatest intensity in the XIII century. Her perceived impact on daily life was tremendous and not surprisingly this extended to the spheres of disease and healing. The purpose of this study is to compare the medical and neuropsychiatric findings in two XIII century Spanish texts of Marian miracles, both examples of the popular Catholicism (vs. official catholic doctrine). We analyzed the medical and neuropsychiatric events in the Cantigas de Santa Maria (Canticles of St. Mary, CSM), composed at the court of Alfonso X and the Milagros de Nuestra Señora (The Miracles of Our Lady, MNS), written by Gonzalo de Berceo. Among the 25 miracles reported in the MNS, medically relevant facts were addressed in 19 miracles with a total of 23 recorded events (including resurrection or escape from death in five) and demonic possession in three (one with witchcraft/deicide). The most common medical subjects were ergotism, obstetric-gynecological, sudden death, intellectual disability/illiteracy, encephalopathy/alcohol intoxication, suicide (with self-mutilation/castration), infanticide, infections, and absence of body decomposition after death. The 427 canticles in the CSM contain 270 medically relevant facts. Neuropsychiatric conditions were alluded to in 98 songs. Blindness and dystonia/weakness/deformities were the most common phenomena. Illuminations detailed many of the medical facts in the CSM, but not in the MNS. Medically relevant facts were described in both texts, but with more details in the CSM. Neurological conditions were more often described in the CSM, psychiatric conditions in the MNS.

Espanol para Hoteleria y Turismo = Spanish for Travel and Tourism.

Science.gov (United States)

Montes, Yara G.

This beginning through advanced Spanish text includes grammar explanations, readings, and exercises with the emphasis on situations involving travel and tourism. The introductory lesson covers the Spanish language, the importance of Spanish in the United States, the Spanish alphabet, pronunciation, capitalization, punctuation, syllabication,…

Preliminary tank characterization report for single-shell tank 241-BX-102: best-basis inventory

International Nuclear Information System (INIS)

Kupfer, M.J.

1997-01-01

An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-BX-102 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task

Preliminary tank characterization report for single-shell tank 241-BX-111: best-basis inventory

International Nuclear Information System (INIS)

Kupfer, M.J.

1997-01-01

An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-BX-111 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task

The Challenges of Spanish Language Teaching in Multilingual India: A Case Study of Delhi

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Dhiraj Kumar Rai

2017-12-01

Full Text Available The multilingual surrounding of Spanish Language Teaching (SLT in India has presented a unique linguistic principle. This principle relies upon the application of English language instructions (as FL1 to combine several methods for teaching-learning Spanish language (as FL2. However, the effectiveness and appropriateness of this linguistic principle, whereby English language instructions are used for SLT, remain undiagnosed. In fact, the technique of SLT in India needs to take into account the local linguistic or dialectical make-up of the actual or potential learners. As such, the process of Spanish Language acquisition in India as inspired by an exposure to local languages/dialects needs to be creatively explored. Furthermore, the recently increasing entries of specific Spanish words/terms in the Indian ‘popular language usage’, and their implications for SLT in India require to be sufficiently investigated. This article aims at filling in the above-mentioned lacunae by conducting a case study of the status of Spanish Language Teaching in Delhi. It draws the conclusion that the maximum flexibility in the process of eclectically mixing various pedagogical methods of SLT could go a long way in motivating and benefitting both the teachers as well as the students, thereby enhancing the overall efficiency of SLT in multilingual India.

77 FR 30566 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

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2012-05-23

... those in the Grandfathered Rules. These BX disciplinary procedures provide fair procedures for the... now govern the disciplinary process for any legacy disciplinary matter. Under Chapter XXX, an... Constitution Provisions where appropriate, and to reflect that the disciplinary and arbitration procedures will...

Hepatitis Bx Antigen Stimulates Expression of a Novel Cellular Gene, URG4, that Promotes Hepatocellular Growth and Survival

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N. Lale Satiroglu Tufan

2002-01-01

Full Text Available Hepatitis B virus encoded X antigen (HBxAg may contribute to the development of hepatocellular carcinoma (HCC by up-or downregulating the expression of cellular genes that promote cell growth and survival. To test this hypothesis, HBxAg-positive and-negative HepG2 cells were constructed, and the patterns of cellular gene expression compared by polymerase chain reaction select cDNA subtraction. The full-length clone of one of these upregulated genes (URG, URG4, encoded a protein of about 104 kDa. URG4 was strongly expressed in hepatitis 13-infected liver and in HCC cells, where it costained with HBxAg, and was weakly expressed in uninfected liver, suggesting URG4 was an effector of HBxAg in vivo. Overexpression of URG4 in HepG2 cells promoted hepatocellular growth and survival in tissue culture and in soft agar, and accelerated tumor development in nude mice. Hence, URG4 may be a natural effector of HBxAg that contributes importantly to multistep hepatocarcinogenesis.

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2012-08-07

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2010-11-12

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To the Spanish Young People: Don Quixote Dreyfussard

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Virginia Ramírez Martín

2013-12-01

Full Text Available In 1898, Spanish press take up part of its pages with a relevant international issue: the Dreyfus affair. The case was widely covered by Spanish newspapers, in special by Don Quijote, a Madrilenian satiric press, whose Director promoted a campaign in favour of Zola collecting signatures in order to the French litterateur was aware that Spain was close to him. This initiative is completed with a call to Spanish young people who is illustrated with a quixotic caricature. Cervantine character personifies the idea of justice getting to transmit during the Spanish crisis at the end of the nineteenth century the image of the nobleman forged by Spanish stereotypical, like a crusader fighting for a noble cause, thus turning Don Quixote into another dreyfussard.

Spanish Verbs Visualization: A study and scalable experimentation

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Ana García Serrano

2016-12-01

Full Text Available In this paper it is presented a study on verbs in Spanish and it’s potential to display images from the Wikipedia (Wikimedia. It is designed and developed an Information Retrieval model based on linguistic structures of verbs and an environment that allows all subsequent scaling Spanish verbs. Adesse and EuroWordNet are the linguistic resources selected to bring the theoretical basis of the work. In the absence of an adequate corpus with relevant judgments to the problem, it has been recorded by the second author a subset of visual verbs sufficiently representative and enable to further work on this issue. Finally conclusions about visual verbs as well as the obtained results are provided

Geometry of BxB-orbit closures in equivariant embeddings

DEFF Research Database (Denmark)

He, X.; Thomsen, Jesper Funch

2005-01-01

Let X denote an equivariant embedding of a connected reductive group G over an algebraically closed field k. Let B denote a Borel subgroup of G and let Z denote a BxB-orbit closure in X. When the characteristic of k is positive and X is projective we prove that Z is globally F-regular. As a conse......-regular. As a consequence, Z is normal and Cohen-Macaulay for arbitrary X and arbitrary characteristics. Moreover, in characteristic zero it follows that Z has rational singularities. This extends earlier results by the second author and M. Brion....

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2012-05-23

... discovery, and in fact may create investor confusion about the extent of trading interest in a stock. In... multiple orders at different price levels to move the price of a stock. While BX has an active program to... manipulation. The fee will be imposed on market participant identifiers (``MPID'') that have characteristics...

4,4’-Bis(4-octylphenoxy-2,2’-bipyridine

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Zhen-Ting Du

2009-12-01

Full Text Available 4,4’-Bis(4-octylphenoxy-2,2’-bipyridine which can be used in complexes of ruthenium was synthesized. This ligand bears a long chain for the purpose of increasing the solubility of the final complex. The synthesis was achieved through a nucleophilic aromatic substitution reaction of 4,4’-bromo-2,2’-bipyridine and 4-octylphenol.

Determining Factors for Stress Perception Assessed with the Perceived Stress Scale (PSS-4) in Spanish and Other European Samples.

Science.gov (United States)

Vallejo, Miguel A; Vallejo-Slocker, Laura; Fernández-Abascal, Enrique G; Mañanes, Guillermo

2018-01-01

Objective: Stress perception depends on cultural and social aspects that vary from one country to another. One of the most widely disseminated methods of assessing psychological stress is the Perceived Stress Scale (PSS-4). Therefore, in order to identify these factors and their impact on mental health, the present study compares the PSS-4 results among three European countries (Great Britain, France and Spain). This study focuses on PSS-4 results within a Spanish sample to determine: (1) normative data, reliability and validity of PSS-4 in a Spanish sample and (2) how stress perception changes depending on cultural and social factors. Methods: The data were obtained from a website representing a service of a smoking cessation program, the study represented a service that was open to all individuals. The number of participants were 37,451. They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R). Results: The PSS-4 scores could differentiate between relevant sociodemographic variables (such as sex, age, nationality, marital status, education, parental status, employment status, and income class). The PSS-4 scores showed a positive correlation with the SCL 90-R anxiety and depression scales. The normed values for interpreting the PSS-4 scores are presented. The PSS-4 showed adequate internal consistency and reliability. Conclusions: The PSS-4 is a useful instrument for assessing stress perception levels in the general population in different countries. Its internal consistency is sufficient for a 4-item scale.

Dynamic Chemical Model for $\\text {H} _2 $/$\\text {O} _2 $ Combustion Developed Through a Community Workflow

KAUST Repository

Oreluk, James; Needham, Craig D.; Baskaran, Sathya; Sarathy, Mani; Burke, Michael P.; West, Richard H.; Frenklach, Michael; Westmoreland, Phillip R.

2018-01-01

Elementary-reaction models for $\\text{H}_2$/$\\text{O}_2$ combustion were evaluated and optimized through a collaborative workflow, establishing accuracy and characterizing uncertainties. Quantitative findings were the optimized model, the importance of $\\text{H}_2 + \\text{O}_2(1\\Delta) = \\text{H} + \\text{HO}_2$ in high-pressure flames, and the inconsistency of certain low-temperature shock-tube data. The workflow described here is proposed to be even more important because the approach and publicly available cyberinfrastructure allows future community development of evolving improvements. The workflow steps applied here were to develop an initial reaction set using Burke et al. [2012], Burke et al. [2013], Sellevag et al. [2009], and Konnov [2015]; test it for thermodynamic and kinetics consistency and plausibility against other sets in the literature; assign estimated uncertainties where not stated in the sources; select key data targets (

Dynamic Chemical Model for $\\text {H} _2 $/$\\text {O} _2 $ Combustion Developed Through a Community Workflow

KAUST Repository

Oreluk, James

2018-01-30

Elementary-reaction models for $\\\\text{H}_2$/$\\\\text{O}_2$ combustion were evaluated and optimized through a collaborative workflow, establishing accuracy and characterizing uncertainties. Quantitative findings were the optimized model, the importance of $\\\\text{H}_2 + \\\\text{O}_2(1\\\\Delta) = \\\\text{H} + \\\\text{HO}_2$ in high-pressure flames, and the inconsistency of certain low-temperature shock-tube data. The workflow described here is proposed to be even more important because the approach and publicly available cyberinfrastructure allows future community development of evolving improvements. The workflow steps applied here were to develop an initial reaction set using Burke et al. [2012], Burke et al. [2013], Sellevag et al. [2009], and Konnov [2015]; test it for thermodynamic and kinetics consistency and plausibility against other sets in the literature; assign estimated uncertainties where not stated in the sources; select key data targets (

Evolution of diagnostic reference levels in Spanish intraoral radiology

International Nuclear Information System (INIS)

Alcaraz, M.; Velasco, F.; Martinez-Beneyto, Y.; Alcaraz-Saura, M.; Velasco, E.; Achel, G. D.; Canteras, M.

2008-01-01

A total of 16 175 official reports of quality assurance on dental radiodiagnostic surgeries from 16 Spanish autonomous regions compiled during 2002-09 were studied to determine the evolution of diagnostic reference levels (DRLs) for obtaining a diagnostic image in the normal conditions of clinical practice in Spanish dental clinics. A DRL of 3.1 mGy was set in 2009, which represents a 35.4 % decrease compared with the dose determined in 2002 (4.8 mGy). During the same period, the mean dose fell by only 17.2 %. The DRL recommended by the European Union in 2004 for intraoral radiology is 4 mGy, and this study shows that 83.4 % of the installations used a dose below this. Of the installations using indirect or direct digital systems 1.1 and 1.2 %, respectively, used doses higher than those recommended, while 14.2 % of those using radiographic film exceeded this limit. (authors)

OSCAR4: a flexible architecture for chemical text-mining

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Jessop David M

2011-10-01

Full Text Available Abstract The Open-Source Chemistry Analysis Routines (OSCAR software, a toolkit for the recognition of named entities and data in chemistry publications, has been developed since 2002. Recent work has resulted in the separation of the core OSCAR functionality and its release as the OSCAR4 library. This library features a modular API (based on reduction of surface coupling that permits client programmers to easily incorporate it into external applications. OSCAR4 offers a domain-independent architecture upon which chemistry specific text-mining tools can be built, and its development and usage are discussed.

75 FR 54665 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To...

Science.gov (United States)

2010-09-08

... with the Exchange's corporate governance standards and the application of the Exchange's public... BX corporate governance requirements are generally comparable to those of the other exchanges. The... corporate governance requirements and any quantitative deficiency which does not contain a compliance period...

Reaching Spanish-speaking smokers online: a 10-year worldwide research program

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Ricardo Felipe Muñoz

2014-06-01

Full Text Available OBJECTIVE: To describe a 10-year proof-of-concept smoking cessation research program evaluating the reach of online health interventions throughout the Americas. METHODS: Recruitment occurred from 2002 - 2011, primarily using Google.com AdWords. Over 6 million smokers from the Americas entered keywords related to smoking cessation; 57 882 smokers (15 912 English speakers and 41 970 Spanish speakers were recruited into online self-help automated intervention studies. To examine disparities in utilization of methods to quit smoking, cessation aids used by English speakers and Spanish speakers were compared. To determine whether online interventions reduce disparities, abstinence rates were also compared. Finally, the reach of the intervention was illustrated for three large Spanish-speaking countries of the Americas-Argentina, Mexico, and Peru-and the United States of America. RESULTS: Few participants had utilized other methods to stop smoking before coming to the Internet site; most reported using no previous smoking cessation aids: 69.2% of Spanish speakers versus 51.8% of English speakers (P < 0.01. The most used method was nicotine gum, 13.9%. Nicotine dependence levels were similar to those reported for in-person smoking cessation trials. Overall observed quit rate for English speakers was 38.1% and for Spanish speakers, 37.0%; quit rates in which participants with missing data were considered to be smoking were 11.1% and 10.6%, respectively. Neither comparison was significantly different. CONCLUSIONS: The systematic use of evidence-based Internet interventions for health problems could have a broad impact throughout the Americas, at little or no cost to individuals or to ministries of health.

75 FR 21083 - Self-Regulatory Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of...

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2010-04-22

... rule consolidation process, FINRA recently made several changes to its financial responsibility rules... 9559 to conform BX's rules to recent changes to the rules of the Financial Industry Regulatory...' financial responsibilities and the rules concerning expedited hearings in light of changes made to the...

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2010-02-19

... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To... Influence Market Prices, Other than Paid Advertising); and 9810 (Initiation of Proceeding) to reflect recent... (Payment Designed to Influence Market Prices, Other than Paid Advertising); and 9810 (Initiation of...

Synchronous Computer-Mediated Dynamic Assessment: A Case Study of L2 Spanish Past Narration

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Darhower, Mark Anthony

2014-01-01

In this study, dynamic assessment is employed to help understand the developmental processes of two university Spanish learners as they produce a series of past narrations in a synchronous computer mediated environment. The assessments were conducted in six weekly one-hour chat sessions about various scenes of a Spanish language film. The analysis…

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2012-05-25

... than Nasdaq. (a)-(e) (f) The term ``Order Type'' shall mean the unique processing prescribed for... cross the quotation of an external market, the order will be priced to the current low offer (for bids... Statutory Basis for, the Proposed Rule Change 1. Purpose BX is proposing to clarify the effect that the...

Differences of statin activity in 2D and 3D pancreatic cancer cell cultures

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Paškevičiūtė M

2017-11-01

Full Text Available Miglė Paškevičiūtė,1 Vilma Petrikaitė1,21Department of Drug Chemistry, Faculty of Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania; 2Department of Biothermodynamics and Drug Design, Vilnius University Institute of Biotechnology, Vilnius, LithuaniaPurpose: To evaluate the anticancer activity of lovastatin (LOVA, mevastatin (MEVA, pitavastatin (PITA, and simvastatin (SIMVA in 2D and 3D models of three human pancreatic cancer cell lines (BxPC-3, MIA PaCa-2, and PANC-1.Methods: The effect of statins on cell viability was estimated by 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide test. The activity of statins in 3D pancreatic cancer cell cultures was examined by measuring the size change of spheroids. The type of cell death was identified by cell staining with Hoechst 33342 and propidium iodide. The activity of statins on the clonogenicity of cancer cells was tested by evaluating the effect on the colony-forming ability of cells.Results: The rank order of the activity of tested statins on cell viability was as follows: PITA > SIMVA > LOVA > MEVA. Among the tested statins, PITA had the greatest effect on cell viability (half maximal effective concentration values after 72 h on BxPC-3, MIA PaCa-2, and PANC-1 cells were 1.4±0.4 µM, 1.0±0.2 µM, and 1.0±0.5 µM, respectively. PITA also showed the strongest effect on tumor spheroid growth. Statins suppressed the colony formation of cancer cells. PITA demonstrated the greatest reduction in colony size and number. Apoptosis and necrosis assay results showed that at lower concentrations statins mostly induced cell death through apoptosis, whereas higher concentrations of compounds activated also necrotic processes.Conclusion: Statins, especially PITA, demonstrate an anticancer activity against pancreatic cancer cell lines BxPC-3, MIA PaCa-2, and PANC-1 in both 2D and 3D models.Keywords: HMG-CoA reductase, cell viability, spheroid, apoptosis

The Índice Flesch-Szigriszt and Spanish Lexile Analyzer to evaluate Spanish patient education materials in otolaryngology.

Science.gov (United States)

Nassif, Samih J; Wong, Kevin; Levi, Jessica R

2018-01-01

Evaluate the reading difficulty of Spanish patient education materials using the validated Índice Flesch-Szigriszt (INFLESZ) and Spanish Lexile Analyzer, and to identify relationships between English and Spanish readability formulas. Cross-sectional analysis. All otolaryngology-related patient education articles written in Spanish from the health libraries of the top 10 US News & World Report-ranked hospitals, top 10 Doximity-ranked otolaryngology residencies, the American Academy of Otolaryngology-Head and Neck Surgery website, and the US National Library of Medicine online section on ears, nose and throat were collected. Reading difficulty was assessed using the INFLESZ and Spanish Lexile Analyzer. Additional readability assessments included the traditional English tools: Flesch-Kincaid Grade Level, Flesch Reading Ease Score, and the Simple Measure of Gobbledygook score. A total of 497 articles were reviewed. The average INFLESZ score for all articles was 57.75, which is considered normal and requires the reading ability of a student who finished Escuela Secundaria Obligatoria or 10th grade equivalent in the United States. The average Spanish Lexile measure for all articles was 1062L, equivalent to a reading level between the 6th and 12th grade. English readability tools calculated a more difficult reading level compared to Spanish tools when performed on the same text. Current Spanish patient education materials in otolaryngology may be too difficult for the average Spanish-speaking reader to understand. Future improvements may be warranted to improve the readability of educational materials and increase health literacy. NA. Laryngoscope, 128:E21-E26, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Validity and reliability of the Spanish version of the Organizational Readiness for Knowledge Translation (OR4KT questionnaire

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Gonzalo Grandes

2017-11-01

Full Text Available Abstract Background Organizational readiness to change healthcare practice is a major determinant of successful implementation of evidence-based interventions. However, we lack of comprehensive, valid, and reliable instruments to measure it. We assessed the validity and reliability of the Spanish version of the Organizational Readiness for Knowledge Translation (OR4KT questionnaire in the context of the implementation of the Prescribe Vida Saludable III project, which seeks to strengthen health promotion and chronic disease prevention in primary healthcare organizations of the Osakidetza (Basque Health Service, Spain. Methods A cross-sectional study was conducted including 127 professionals from 20 primary care centers within Osakidetza. They filled in the OR4KT questionnaire twice in a 15- to 30-day period to test repeatability. In addition, we used the Survey of Organizational Attributes for Primary Care (SOAPC and we documented the number of healthcare professionals who formally engaged in the Prescribe Vida Saludable III project within each participating center to assess concurrent validity. Results Cronbach’s alpha for the overall OR4KT was .95, and the overall repeatability coefficient was 6.95%, both excellent results. Confirmatory factor analysis supported the underlying theoretical structure of 6 dimensions and 23 sub-dimensions. There were positive moderate-to-high internal correlations between these six dimensions, and there was evidence of good concurrent validity (correlation coefficient of .76 with SOAPC, and .80 with the proportion of professionals engaged by center. A score higher than 64 (out of 100 would be indicative of an organization with high level of readiness to implement the intervention (sensitivity = .75, specificity = 1. Conclusions The Spanish version of the OR4KT exhibits very strong reliability and good validity, although it needs to be validated in a larger sample and in different implementation contexts.

Molecular epidemiology, genotype-phenotype correlation and BH4 responsiveness in Spanish patients with phenylketonuria.

Science.gov (United States)

Aldámiz-Echevarría, Luis; Llarena, Marta; Bueno, María A; Dalmau, Jaime; Vitoria, Isidro; Fernández-Marmiesse, Ana; Andrade, Fernando; Blasco, Javier; Alcalde, Carlos; Gil, David; García, María C; González-Lamuño, Domingo; Ruiz, Mónica; Ruiz, María A; Peña-Quintana, Luis; González, David; Sánchez-Valverde, Felix; Desviat, Lourdes R; Pérez, Belen; Couce, María L

2016-08-01

Phenylketonuria (PKU), the most common inborn error of amino acid metabolism, is caused by mutations in the phenylalanine-4-hydroxylase (PAH) gene. This study aimed to assess the genotype-phenotype correlation in the PKU Spanish population and the usefulness in establishing genotype-based predictions of BH4 responsiveness in our population. It involved the molecular characterization of 411 Spanish PKU patients: mild hyperphenylalaninemia non-treated (mild HPA-NT) (34%), mild HPA (8.8%), mild-moderate (20.7%) and classic (36.5%) PKU. BH4 responsiveness was evaluated using a 6R-BH4 loading test. We assessed genotype-phenotype associations and genotype-BH4 responsiveness in our population according to literature and classification of the mutations. The mutational spectrum analysis showed 116 distinct mutations, most missense (70.7%) and located in the catalytic domain (62.9%). The most prevalent mutations were c.1066-11G>A (9.7%), p.Val388Met (6.6%) and p.Arg261Gln (6.3%). Three novel mutations (c.61-13del9, p.Ile283Val and p.Gly148Val) were reported. Although good genotype-phenotype correlation was observed, there was no exact correlation for some genotypes. Among the patients monitored for the 6R-BH4 loading test: 102 were responders (87, carried either one or two BH4-responsive alleles) and 194 non-responders (50, had two non-responsive mutations). More discrepancies were observed in non-responders. Our data reveal a great genetic heterogeneity in our population. Genotype is quite a good predictor of phenotype and BH4 responsiveness, which is relevant for patient management, treatment and follow-up.

Spanish ATLAS Tier-2 facing up to Run-2 period of LHC

CERN Document Server

Gonzalez de la Hoz, Santiago; The ATLAS collaboration; Fassi, Farida; Fernandez Casani, Alvaro; Kaci, Mohammed; Lacort Pellicer, Victor Ruben; Montiel Gonzalez, Almudena Del Rocio; Oliver Garcia, Elena; Pacheco Pages, Andres; Salt, José; Villaplana Perez, Miguel; Sanchez Martinez, Victoria; Sánchez, Javier

2015-01-01

The goal of this work is to describe the way of addressing the main challenges of Run-2 by the Spanish ATLAS Tier-2. The considerable increase of energy and luminosity for the upcoming Run-2 w.r.t. Run-1 has led to a revision of the ATLAS computing model as well as some of the main ATLAS computing tools. The adaptation to these changes will be shown, with the peculiarities that it is a distributed Tier-2 composed of three sites and its members are involved on ATLAS computing tasks with a hub of research, innovation and education.

Validating a Spanish Developmental Spelling Test.

Science.gov (United States)

Ferroli, Lou; Krajenta, Marilyn

The creation and validation of a Spanish version of an English developmental spelling test (DST) is described. An introductory section reviews related literature on the rationale for and construction of DSTs, spelling development in the early grades, and Spanish-English bilingual education. Differences between the English and Spanish test versions…

75 FR 4431 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

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2010-01-27

... regulatory operations in the Concept Release Concerning Self-Regulation \\22\\ and the release on the Fair Administration and Governance of Self- Regulatory Organizations.\\23\\ In the Concept Release, the Commission... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61388; File No. SR-BX-2010-001] Self-Regulatory...

75 FR 56618 - Self-Regulatory Organizations; BATS Exchange, Inc.; NASDAQ OMX BX, Inc.; Chicago Board Options...

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2010-09-16

... security and its maximum remaining life). \\62\\ See Android Alpha Fund Letter. \\63\\ See Deutsche Bank Letter... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-62884; File Nos. SR-BATS-2010-018; SR-BX-2010... Stock Exchange, Inc.; EDGA Exchange, Inc.; EDGX Exchange, Inc.; International Securities Exchange LLC...

78 FR 61418 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

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2013-10-03

... using any facility or system which BX operates or controls, and is not designed to permit unfair... and not unfairly discriminatory because the model seeks to reward liquidity providers by assessing... not present an undue burden on competition because the pricing seeks to reward liquidity providers...

Life values structure in a Spanish sample of adolescents

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María Tejerina-Arreal

2014-05-01

Full Text Available We examined the structure of personal life values as a representation of underlying motivation, in a Spanish sample of children and adolescents 12 - 16 years old. In general, results showed that youth put higher priority on intrinsic life goals (meaningful relationships, being physically healthy, self-acceptance than extrinsic life goals (image, money, power. Gender differences were found in specific life goals. When comparing our results with another longitudinal American study using the same instrument and methodology, we found similar results, although Spanish youth value priorities goals related to support rather than striving as in American adolescents. Cultural and age trend in life priorities are discussed.

Generation of human iPSC line GRX-MCiPS4F-A2 from adult peripheral blood mononuclear cells (PBMCs with Spanish genetic background

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Sonia Cabrera

2015-09-01

Full Text Available We have generated iPSCs from peripheral blood mononuclear cells (PBMCs of a healthy man using heat sensitive and non-integrative Sendai virus containing Sox2, Oct3/4, c-Myc and Klf4. Human GRX-MCiPS4F-A2 cell line was established and characterized through this study.

Measuring Disparities: Bias in the SF-36v2 among Spanish-speaking Medical Patients

Science.gov (United States)

Sudano, Joseph J.; Perzynski, Adam; Love, Thomas E.; Lewis, Steven A.; Murray, Patrick M.; Huber, Gail; Ruo, Bernice; Baker, David W.

2011-01-01

Background Many national surveys have found substantial differences in self-reported overall health (SROH) between Spanish-speaking Hispanics and other racial/ethnic groups. However, because cultural and language differences may create measurement bias, it is unclear whether observed differences in SROH reflect true differences in health. Objectives This study uses a cross-sectional survey to investigate psychometric properties of the SF-36v2 for subjects across four racial/ethnic and language groups. Multi-group latent variable modeling was used to test increasingly stringent criteria for measurement equivalence. Subjects Our sample (N = 1281) included 383 non-Hispanic whites, 368 non-Hispanic blacks, 206 Hispanics interviewed in English and 324 Hispanics interviewed in Spanish recruited from outpatient medical clinics in two large urban areas. Results We found weak factorial invariance across the four groups. However, there was no strong factorial invariance. The overall fit of the model was substantially worse (change in CFI > .02, RMSEA change > .003) after requiring equal intercepts across all groups. Further comparisons established that the equality constraints on the intercepts for Spanish-speaking Hispanics were responsible for the decrement to model fit. Conclusions Observed differences between SF-36v2 scores for Spanish speaking Hispanics are systematically biased relative to the other three groups. The lack of strong invariance suggests the need for caution when comparing SF-36v2 mean scores of Spanish-speaking Hispanics with those of other groups. However, measurement equivalence testing for this study supports correlational or multivariate latent variable analyses of SF-36v2 responses across all four subgroups, since these analyses require only weak factorial invariance. PMID:21430580

Graphic Arts. A Bilingual Text = Artes Graficas. Un Texto Bilingue.

Science.gov (United States)

Los Angeles Unified School District, CA. Div. of Career and Continuing Education.

This bilingual instructional text, one in a series of six texts covering various vocational and technical topics, provides secondary level English and Spanish instruction in graphic arts. Addressed in the individual sections are basic graphic arts (composition, stone and press work, offset printing, silk screen, and photography) and allied graphic…

Test plan for headspace gas concentration measurement and headspace ventilation rate measurement for DCRTs 241-A-244, 241-BX-244, 241-S-244, 241-TX-244

International Nuclear Information System (INIS)

Bauer, R.E.

1998-01-01

This test plan provides the directions to characterize the headspace gas concentrations and the headspace ventilation rate for double contained receiver tanks 241-A-244, 241-BX-244, 241-S-244, and 241-TX-244

Dicty_cDB: SSK653 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available sequence. 40 0.26 2 AB048748 |AB048748.1 Bactrocera cucurbitae mitochondrial genes for 16S rRNA, tRNA-Val, 1...urbitae mitochondrial genes for 16S rRNA, tRNA-Val, 12S rRNA, partial and complete ... BX120013 |BX120013.4 Zebrafish DNA sequence *** SEQUENCING IN PROGRESS *** from clone. 34 0.23 5 AB048754 |AB048754.1 Bactrocera cuc

Celebrations III and IV Centenary of Don Quixote in Spanish America through the Spanish press from 1905 to 2005

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María Ángeles Chaparro Domínguez

2012-12-01

Full Text Available This article analyzes the coverage that the Spanish press provided to Spanish American celebrations for the Third and Fourth Centenary of the publication of the first part of Don Quixote, events that took place in 1905 and 2005, respectively. By the study of a total of twenty-one newspapers, which include El Imparcial, El Liberal and La Correspondencia de España, of the first period, and El País, El Mundo and La Vanguardia of the second, we will find out how they lived both centenaries in Spanish America, how important were these tributes in the press and, furthermore, we will know the concrete symbolic meaning that the popular Spanish nobleman acquired in either period.

Ship’s biographies as a source of the Spanish-Russian naval cooperation

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Nicholas W. Mitiukov

2016-03-01

Full Text Available On the basis of previously published author’s works about biographies of individual ships, considered Russian-Spanish ship’s exchange as an aspect of naval cooperation between Russia and Spain. There is offer a periodization of this process. The first period (1810-1820-s. associated with the sale for the Spanish fleet the Russian Baltic Fleet at the end of the Napoleonic wars, that reasons were on the needing to regain the Spanish colonies in Latin America. On two parties there were purchased five battleships and six frigates. The second period (1904-1917 associated with negotiations for the purchasing for Russian a Spanish warships during the Russian-Japanese war, and the acquisition of five Spanish trawlers in 1915 for the needs of the Arctic Ocean Flotilla. The third period (1936-1939 – mutual capture of merchant vessels and the Soviet aid for Republican Spain, when it was handed over to four torpedo boats G-5-class, two of which at the end of the Civil War were served in the Nationalists Navy.

78 FR 48748 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

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2013-08-09

... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To...-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule Change The Exchange... managing their orders in the event of symbol changes and changes in listing venue, by cancelling open...

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2011-08-02

... Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Increase... the Rules of the Boston Options Exchange Group, LLC (``BOX'') to increase the position limit for... proposed change would have the effect of increasing the exercise limits for options on SPDRs[reg]. Chapter...

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2013-03-12

... the last ten years, however, Distributors have improved the technical delivery and monitoring of data... Recipients by contractually restricting the data flow and monitoring the delivery. Thus, offering MDS on BX... witnessed competitors creating new products and innovative pricing in this space over the course of the past...

78 FR 19763 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

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2013-04-02

... assess the same Routing Fees to all non-Customer market participants. Under its flat fee structure... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change... Organization's Statement of the Terms of Substance of the Proposed Rule Change The Exchange proposes to amend...

Politicians through the press: a Spanish case study during 2008-2012

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María Navarro Sorolla

2017-07-01

Full Text Available The press cover the politicians’ message and grant them a degree of media visibility, insinuating more or less support for any given party and giving the general public a particular vision of the political class through the media influence on politics. This paper is the result of a study of national coverage of politics (2008-2012, as published in two leading Spanish media sources (El País and El Mundo, with a particular emphasis on the Popular Party (PP and the Spanish Social Workers’ Party (PSOE. The research considers whether the media give a political use to political information through media negativity. The conclusion was that both daily newspapers use the information in a biased and negative way when dealing with Spanish political information

Do cultural differences influence batterer intervention program outcomes? A studywith Spanish and Latin American offenders

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Viviana Vargas

2015-04-01

Full Text Available This study analyzed, first, if there were any differences in attitudes towards partner violence (i.e., perceivedseverity, victim blaming, and acceptability, responsibility attributions, sexism, and risk of recidivismbetween Latin American immigrants and Spanish offenders convicted of intimate-partner violence at thebeginning of a batterer intervention program. Second, differences in the batterer intervention programoutcomes between Spanish and Latin American offenders were explored. The sample consisted of 278batterers (211 Spanish and 67 Latin American who participated in a community-based battererintervention program. Results showed significant differences between Spanish and Latin Americanoffenders in perceived severity, victim blaming, violence against women acceptability, and benevolentsexism. Regarding batterer intervention program outcomes, results showed that despite initial differencesbetween Spanish and Latin American offenders, both groups benefit equally from the intervention.

Negative differential resistance and switch behavior of T-BxNy (x, y = 5, 6, 11) molecular junctions

Science.gov (United States)

Wang, Shi-Liang; Yang, Chuan-Lu; Wang, Mei-Shan; Ma, Xiao-Guang; Xin, Jian-Guo

2017-05-01

The electronic transport properties of T-BxNy (x, y = 5, 6, 11) molecular junction are investigated based on first-principle density functional theory and non-equilibrium Green's function method. Strong negative differential resistance (NDR) behavior is observed for T-B5N6 molecule under negative and positive bias voltages, with an obvious switch effect for T-B6N5. However, only small NDR is shown for the complex of the two molecules. The projected device density of states, the spatial distribution of molecular orbitals, and the effect of transmission spectra under various bias voltages on the electronic transport properties are analyzed. The obvious effect of bias voltage on the changes in the electronic distribution of frontier molecular orbitals is responsible for the NDR or switch behavior. Therefore, different functional molecular devices can be obtained with different structures of T-BxNy.

Educational climate perception by preclinical and clinical medical students in five Spanish medical schools.

Science.gov (United States)

Palés, Jorge; Gual, Arcadi; Escanero, Jesús; Tomás, Inmaculada; Rodríguez-de Castro, Felipe; Elorduy, Marta; Virumbrales, Montserrat; Rodríguez, Gerardo; Arce, Víctor

2015-06-08

The purpose of this study was to investigate student's perceptions of Educational Climate (EC) in Spanish medical schools, comparing various aspects of EC between the 2nd (preclinical) and the 4th (clinical) years to detect strengths and weaknesses in the on-going curricular reform. This study utilized a cross-sectional design and employed the Spanish version of the "Dundee Ready Education Environment Measure" (DREEM). The survey involved 894 2nd year students and 619 4th year students from five Spanish medical schools. The global average score of 2nd year students from the five medical schools was found to be significantly higher (116.2±24.9, 58.2% of maximum score) than that observed in 4th year students (104.8±29.5, 52.4% of maximum score). When the results in each medical school were analysed separately, the scores obtained in the 2nd year were almost always significantly higher than in the 4th year for all medical schools, in both the global scales and the different subscales. The perception of the EC by 2nd and 4th year students from five Spanish medical schools is more positive than negative although it is significantly lower in the 4th year. In both years, although more evident in the 4th year, students point out the existence of several important "problematic educational areas" associated with the persistence of traditional curricula and teaching methodologies. Our findings of this study should lead medical schools to make a serious reflection and drive the implementation of the necessary changes required to improve teaching, especially during the clinical period.

Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0 and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants

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Roser Granero

2018-05-01

Full Text Available Aims: Due to the increasing evidence of shared vulnerabilities between addictive behaviors and excessive food intake, the concept of food addiction in specific clinical populations has become a topic of scientific interest. The aim of this study was to validate the Yale Food Addiction Scale (YFAS 2.0 in a Spanish sample. We also sought to explore food addiction and its clinical correlates in eating disorder (ED and gambling disorder (GD patients.Methods: The sample included 301 clinical cases (135 ED and 166 GD, diagnosed according to DSM-5 criteria, and 152 healthy controls (HC recruited from the general population.Results: Food addiction was more prevalent in patients with ED, than in patients with GD and HC (77.8, 7.8, and 3.3%, respectively. Food addiction severity was associated with higher BMI, psychopathology and specific personality traits, such as higher harm avoidance, and lower self-directedness. The psychometrical properties of the Spanish version of the YFAS 2.0 were excellent with good convergent validity. Moreover, it obtained good accuracy in discriminating between diagnostic subtypes.Conclusions: Our results provide empirical support for the use of the Spanish YFAS 2.0 as a reliable and valid tool to assess food addiction among several clinical populations (namely ED and GD. The prevalence of food addiction is heterogeneous between disorders. Common risk factors such as high levels of psychopathology and low self-directedness appear to be present in individuals with food addiction.

Rethinking Spanish: Understanding Spanish Speakers Motivations and Reasons to Opt for Either an English Only or a Dual English-Spanish Educational Program

Science.gov (United States)

Wright, Adrienne C.

2017-01-01

Spanish-speaking parents choose to enroll their children in either an English only or English-Spanish dual immersion program when presented with both choices. This ethnographic study explored parent's perceptions of the purpose, advantages, and disadvantages of learning in school in English only or in a dual English-Spanish. Through focus group…

16 CFR 455.5 - Spanish language sales.

Science.gov (United States)

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Spanish language sales. 455.5 Section 455.5... § 455.5 Spanish language sales. If you conduct a sale in Spanish, the window form required by § 455.2... vehicle both an English language window form and a Spanish language translation of that form. Use the...

Etiologies and Outcomes of Acute Liver Failure in a Spanish Community

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Emilio Fábrega

2013-01-01

Full Text Available Previous retrospective study (1992 to 2000 performed in Spain showed that drug toxicity, viral hepatitis, and indeterminate etiology were the most prevalent causes of acute liver failure (ALF. In the last decade, there is no information about ALF in our country. For these reasons we analyze retrospectively, in a ten-year period (2000 to 2010, the presumed causes, clinical characteristics, course, and outcome of ALF in a Spanish community. Causes of ALF were indeterminate in 4 patients (24%, acute hepatitis B infection in 4 patients (24%, drug or toxic reactions in 4 patients (24%, including one case of acetaminophen overdose, followed by miscellaneous causes. The overall short-term survival (6 weeks after admission was 65%. Liver transplantation was performed in 11 patients with a survival of 82%. Despite fulfilling criteria, 2 patients were not transplanted because of contraindications; they both died. In summary, acute hepatitis B and indeterminate cause are still being the most frequent causes of ALF in our region, and patients with ALF have an excellent chance of survival after emergency liver transplantation. Acetaminophen overdose still represents a very rare cause of ALF in our community.

Adult Second Language Learning of Spanish Vowels

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Cobb, Katherine; Simonet, Miquel

2015-01-01

The present study reports on the findings of a cross-sectional acoustic study of the production of Spanish vowels by three different groups of speakers: 1) native Spanish speakers; 2) native English intermediate learners of Spanish; and 3) native English advanced learners of Spanish. In particular, we examined the production of the five Spanish…

78 FR 29795 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc ; Notice of Filing of Proposed Rule Change for...

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2013-05-21

...\\ Accordingly, the affiliate relationship between BX and NOS, its member, raises the issue of an exchange's... unfair competitive advantage and potential conflicts of interest between an exchange's self-regulatory... potential for conflicts of interest in instances where a member firm is affiliated with an exchange of which...

76 FR 16844 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

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2011-03-25

... trading in each UTP Derivative Security contain applicable trading hours for the UTP Derivative Security... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-64105; File No. SR-BX-2011-016] Self-Regulatory... Starting Time March 22, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934 (``Act...

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2012-03-22

... and benefit from BOX routing services for Public Customer Orders at no charge. While the changes to... communications relating to the proposed rule change between the Commission and any person, other than those that... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To...

Partition of Ni between olivine and sulfide: the effect of temperature, f_{{text{O}}_{text{2}} } and f_{{text{S}}_{text{2}} }

Science.gov (United States)

Fleet, M. E.; Macrae, N. D.

1987-03-01

The experimental distribution coefficient for Ni/ Fe exchange between olivine and monosulfide (KD3) is 35.6±1.1 at 1385° C, f_{{text{O}}_{text{2}} } = 10^{ - 8.87} ,f_{{text{S}}_{text{2}} } = 10^{ - 1.02} , and olivine of composition Fo96 to Fo92. These are the physicochemical conditions appropriate to hypothesized sulfur-saturated komatiite magma. The present experiments equilibrated natural olivine grains with sulfide-oxide liquid in the presence of a (Mg, Fe)-alumino-silicate melt. By a variety of different experimental procedures, K D3 is shown to be essentially constant at about 30 to 35 in the temperature range 900 to 1400° C, for olivine of composition Fo97 to FoO, monosulfide composition with up to 70 mol. % NiS, and a wide range of f_{{text{O}}_{text{2}} } and f_{{text{S}}_{text{2}} }.

48 CFR 252.222-7004 - Compliance with Spanish social security laws and regulations.

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2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Compliance with Spanish... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.222-7004 Compliance with Spanish social... Spanish Social Security Laws and Regulations (JUN 1997) (a) The Contractor shall comply with all Spanish...

R and D program of the Spanish National Company for Radioactive Wastes management

International Nuclear Information System (INIS)

Astudillo, J.

1993-01-01

The second R+D program of the Spanish National Company for Radioactive Wastes Management (ENRESA) has a whole budget of 56 million $ for the period 1991-1995. This program is included within the Spanish Energy Plan (PEN-91) and encompasses four main areas: 1) Low and medium level radioactive wastes 2) High level radioactive wastes 3) Decommissioning and dismantling of nuclear installations 4) Radiological protection The Spanish program is coordinated with policies of international organizations: CEC,OECD and IAEA

Initial validation of the Argentinean Spanish version of the PedsQL™ 4.0 Generic Core Scales in children and adolescents with chronic diseases: acceptability and comprehensibility in low-income settings

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Bauer Gabriela

2008-08-01

Full Text Available Abstract Background To validate the Argentinean Spanish version of the PedsQL™ 4.0 Generic Core Scales in Argentinean children and adolescents with chronic conditions and to assess the impact of socio-demographic characteristics on the instrument's comprehensibility and acceptability. Reliability, and known-groups, and convergent validity were tested. Methods Consecutive sample of 287 children with chronic conditions and 105 healthy children, ages 2–18, and their parents. Chronically ill children were: (1 attending outpatient clinics and (2 had one of the following diagnoses: stem cell transplant, chronic obstructive pulmonary disease, HIV/AIDS, cancer, end stage renal disease, complex congenital cardiopathy. Patients and adult proxies completed the PedsQL™ 4.0 and an overall health status assessment. Physicians were asked to rate degree of health status impairment. Results The PedsQL™ 4.0 was feasible (only 9 children, all 5 to 7 year-olds, could not complete the instrument, easy to administer, completed without, or with minimal, help by most children and parents, and required a brief administration time (average 5–6 minutes. People living below the poverty line and/or low literacy needed more help to complete the instrument. Cronbach Alpha's internal consistency values for the total and subscale scores exceeded 0.70 for self-reports of children over 8 years-old and parent-reports of children over 5 years of age. Reliability of proxy-reports of 2–4 year-olds was low but improved when school items were excluded. Internal consistency for 5–7 year-olds was low (α range = 0.28–0.76. Construct validity was good. Child self-report and parent proxy-report PedsQL™ 4.0 scores were moderately but significantly correlated (ρ = 0.39, p Conclusion Results suggest that the Argentinean Spanish PedsQL™ 4.0 is suitable for research purposes in the public health setting for children over 8 years old and parents of children over 5 years old

Headspace vapor characterization of Hanford waste Tank 241-BX-110: Results from samples collected on 04/30/96

International Nuclear Information System (INIS)

Evans, J.C.; Pool, K.H.; Thomas, B.L.; Olsen, K.B.; Fruchter, J.S.; Silvers, K.L.

1997-01-01

This report describes the analytical results of vapor samples taken from the headspace of the waste storage tank 241-BX-110 (Tank BX-110) at the Hanford Site in Washington State. The results described in this report were obtained to characterize the vapors present in the tank headspace and to support safety evaluations and tank farm operations. The results include air concentrations of selected inorganic and organic analytes and grouped compounds from samples obtained by Westinghouse Hanford Company (WHC) and provided for analysis to Pacific Northwest National Laboratory (PNNL). Analyses were performed by the Vapor Analytical Laboratory (VAL) at PNNL. Analyte concentrations were based on analytical results and, where appropriate, sample volumes provided by WHC. A summary of the inorganic analytes, permanent gases, and total non-methane organic compounds is listed in a table. The three highest concentration analytes detected in SUMMA trademark canister and triple sorbent trap samples are also listed in the table. Detailed descriptions of the analytical results appear in the appendices

Genomic resources for a unique, low-virulence Babesia taxon from China

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Guiquan Guan

2016-10-01

Full Text Available Abstract Background Babesiosis is a socioeconomically important tick-borne disease of animals (including humans caused by haemoprotozoan parasites. The severity of babesiosis relates to host and parasite factors, particularly virulence/pathogenicity. Although Babesia bovis is a particularly pathogenic species of cattle, there are species of Babesia of ruminants that have limited pathogenicity. For instance, the operational taxonomic unit Babesia sp. Xinjiang (abbreviated here as Bx of sheep from China is substantially less virulent/pathogenic than B. bovis is in cattle. Although the reason for this distinctiveness is presently unknown, it is possible that Bx has a reduced ability to adhere to cells or evade/suppress immune responses, which might relate to particular proteins, such as the variant erythrocyte surface antigens (VESAs. Results We sequenced and annotated the 8.4 Mb nuclear draft genome of Bx and compared it with those of B. bovis and B. bigemina by synteny analysis; we also investigated the genetic relationship of Bx with selected Babesia species and related apicomplexans for which genomic datasets are available, and explored the VESA complement in Bx. Conclusions The availability of the Bx genome now provides unique opportunities to elucidate aspects of the molecular biology, biochemistry and physiology of Bx, and to explore the reason(s for its limited virulence and/or apparent ability to evade immune attack by the host animal. Moreover, the present genomic resource and an in vitro culture system for Bx raises the prospect of establishing a functional genomic platform to explore essential genes as new intervention targets against babesiosis.

Description of a Riboflavin Biosynthetic Gene Variant Prevalent in the Phylum Proteobacteria

Science.gov (United States)

Brutinel, Evan D.; Dean, Antony M.

2013-01-01

Riboflavin (vitamin B2) is the precursor of flavin mononucleotide and flavin adenine dinucleotide, which are cofactors essential for a host of intracellular redox reactions. Microorganisms synthesize flavins de novo to fulfill nutritional requirements, but it is becoming increasingly clear that flavins play a wider role in cellular physiology than was previously appreciated. Flavins mediate diverse processes beyond the cytoplasmic membrane, including iron acquisition, extracellular respiration, and interspecies interactions. While investigating the regulation of flavin electron shuttle biosynthesis in the Gram-negative gammaproteobacterium Shewanella oneidensis, we discovered that a riboflavin biosynthetic gene (ribBA) annotated as encoding a bifunctional 3,4-dihydroxy-2-butanone 4-phosphate (DHBP) synthase/GTP cyclohydrolase II does not possess both functions. The novel gene, renamed ribBX here, encodes an amino-terminal DHBP synthase domain. The carboxy-terminal end of RibBX not only lacks GTP cyclohydrolase II activity but also has evolved a different function altogether in S. oneidensis, regulating the activity of the DHBP synthase domain. Phylogenetic analysis revealed that the misannotation of ribBX as ribBA is rampant throughout the phylum Proteobacteria (40% of 2,173 annotated ribBA genes) and that ribBX emerged early in the evolution of this group of microorganisms. We examined the functionality of representative ribBX genes from Beta-, Gamma-, and Epsilonproteobacteria and found that, consistent with sequence-based predictions, the encoded GTP cyclohydrolase II domains lack catalytic activity. The persistence of ribBX in the genomes of so many phylogenetically divergent bacterial species lends weight to the argument that ribBX has evolved a function which lends a selective advantage to the host. PMID:24097946

48 CFR 252.228-7006 - Compliance with Spanish laws and insurance.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Compliance with Spanish... CLAUSES Text of Provisions And Clauses 252.228-7006 Compliance with Spanish laws and insurance. As prescribed at 228.370(e), use the following clause: Compliance with Spanish Laws and Insurance (DEC 1998) (a...

State of Level 2 analyses and severe accident management in Spanish nuclear power plants

International Nuclear Information System (INIS)

Otero, R.

1998-01-01

The state of the PSA/IPE studies in the Spanish NPPs is presented in this report, as well as the plans to implement the severe accident management strategy both in the Spanish BWRs and PWRs. First, the Spanish LWRs are introduced, and the scope of the IPE analyses required by the Spanish Regulatory Commission (CSN) is given. The general overview is completed with the current degree of development for the IPE studies in each plant. In the second part the methods and tools are shown which are used by the Spanish plants to develop their Level 2 analysis. The different strategies for severe accident management adopted by the BWPs and PWRs in Spain are also outlined. The sources and implementation of the Severe Accident Guidelines (SAG) are described. More detail is given in the following chapters to the containment analysis of Trillo (PWR, KWU design) and Cofrentes (BWR/6, GE design) NPPs, whose development is being carried out by IBERDROLA. The analysis which has been performed up to date for Trillo is limited to the Plant Damage State (PDS) definition. However, the main phenomena challenging its containment performance have been identified, and they are summarized here. The Level 2 analysis for Cofrentes is comparatively more developed. The main phenomena and the key equipment affecting its containment behaviour are presented. Finally the conclusions of this report are elaborated. (author)

Screening for bipolar disorders in Spanish-speaking populations: sensitivity and specificity of the Bipolar Spectrum Diagnostic Scale-Spanish Version.

Science.gov (United States)

Vázquez, Gustavo Héctor; Romero, Ester; Fabregues, Fernando; Pies, Ronald; Ghaemi, Nassir; Mota-Castillo, Manuel

2010-01-01

Bipolar disorder is commonly misdiagnosed, perhaps more so in Latin American and Spanish-speaking populations than in the United States. The Bipolar Spectrum Diagnostic Scale (BSDS) is a 19-item screening instrument designed to assist in screening for all types of bipolar disorder. The authors investigated the sensitivity of a Spanish-language version of the BSDS in a cohort of 65 outpatients with a diagnosis of bipolar disorder, based on a semi-structured interview and Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision criteria. To determine specificity, we assessed a control group of 36 outpatients with diagnosis of unipolar major depressive disorder. The overall sensitivity of the BSDS Spanish version with bipolar disorders types I, II, and NOS was 0.70, which was slightly lower than the sensitivity in the study using the English version of the BSDS (0.76). The specificity was 0.89. When the threshold was decreased from 13 to 12, the sensitivity of the Spanish BSDS increased to 0.76 and specificity dropped to 0.81. The Spanish version of the BSDS is promising as a screening instrument in Spanish-speaking populations. Copyright 2010 Elsevier Inc. All rights reserved.

V Congress of Spanish Geochemistry

International Nuclear Information System (INIS)

1993-01-01

This proceedings book present the lectures of V Spanish geochemistry Congress. The sessions were: 1.- Materials geochemistry and geologic process. 2.- Geochemistry prospection 3.- Environmental geochemistry 4.- Isotopic geochemistry 5.- Organic geochemistry 6.- Natural materials geochemistry for industry 7.- Hydrogeochemistry 8.- Mathematical models in geochemistry 9.- Analysis methods in geochemistry 10.-Training of geochemistry 11.-Cosmochemistry

A Tale of Two Empires? The Earl's Court Spanish Exhibition (1889

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Kirsty Hooper

2014-10-01

Full Text Available This paper proposes that the forgotten Earl's Court Spanish Exhibition of 1889 provides a valuable window onto the complex relationship between the British and Spanish Empires at the moment of one's expansion and the other's fragmentation. Part I assesses the limited archival evidence together with media reports from both Spain and Britain to uncover the Exhibition’s origins in London’s Spanish expatriate business community and its takeover by British businessmen with interests in Latin America. Part II reconstructs the Exhibition’s layout and contents in order to explore how the contrasting geocultural logics of Spain’s renewed self-projection as a modern Empire and the longstanding British obsession with Spain’s Islamic past play out in the exhibitionary space and its contents. Part III analyses the rhetorical and imaginative strategies employed in British press coverage of the Exhibition, to argue that their coded representations of Spain and Spanish culture open the door to understanding the Exhibition in the context of Spain’s partial absorption into Britain’s nineteenth-century ‘informal empire.’

Development and Validation of the Marijuana Motives Measure Short Form.

Science.gov (United States)

Mezquita, Laura; Ruiz-Valero, Lucía; Martínez-Gómez, Naiara; Ibáñez, Manuel I; Ortet, Generós

2018-01-15

Marijuana motives are a proximal variable to marijuana use. This research aimed to adapt and validate the short form of the Marijuana Motives Measure (MMM; Simons, Correia, Carey, y Borsari, 1998), the MMM SF, in Spanish.  The sample comprised 232 participants (mean age = 25.11 (7.58), 50.43% males) who had tried marijuana at least once in their lifetime. Item and Rasch analyses were performed to choose the final pool of 15 items. Confirmatory Factor Analysis (CFA) showed an adequate 5-factor structure (S-BX2(80) = 121.30, p = .002; NNFI = .944; CFI = .958; IFI = .959; MFI = .915; RMSEA = .047(0.029, 0.063); AIC = -38.70), and the multi-group CFA between males and females showed acceptable fit indices (S-BX2(160) = 230.01, p = .000; NNFI = .900; CFI = .924; IFI = .927; MFI = .860; RMSEA = .062(.043, .078); AIC = -89.99). The questionnaire indicated metric (S-BX2diff (15) = 13.61, p = .556)), scalar (S-BX2diff (15) = 23.15, p = .081)) and error measurement invariance (S-BX2diff (15) = 8.65, p = .895)) between gender groups. The internal consistencies and ordinal omega of the scales were between .79 and .90. In the regression analysis, enhancement, coping and low conformity motives predicted frequency and quantity of marijuana smoked. The best predictor of frequency and quantity consumed during the heaviest smoking period was enhancement, while coping and, to a lesser extent, low conformity, were the only predictors of cannabis-related problems when marijuana frequency and quantity were controlled for.  The MMM SF shows adequate psychometric properties and is a suitable instrument to assess marijuana motives, especially during time-limited sessions.

Spanish ATLAS Tier-1 &Tier-2 perspective on computing over the next years

CERN Document Server

Gonzalez de la Hoz, Santiago; The ATLAS collaboration

2018-01-01

Since the beginning of the WLCG Project the Spanish ATLAS computer centres have contributed with reliable and stable resources as well as personnel for the ATLAS Collaboration. Our contribution to the ATLAS Tier2s and Tier1s computing resources (disk and CPUs) in the last 10 years has been around 5%, even though the Spanish contribution to the ATLAS detector construction as well as the number of authors are both close to 3%. In 2015 an international advisory committee recommended to revise our contribution according to the participation in the ATLAS experiment. With this scenario, we are optimising the federation of three sites located in Barcelona, Madrid and Valencia, taking into account that the ATLAS collaboration has developed workflows and tools to flexibly use all the resources available to the collaboration, where the Tiered structure is somehow vanishing. In this contribution, we would like to show the evolution and technical updates in the ATLAS Spanish Federated Tier2 and Tier1. Some developments w...

L1 French learning of L2 Spanish past tenses: L1 transfer versus aspect and interface issues

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José Amenós Pons

2017-09-01

Full Text Available This paper examines the process of acquiring L2s that are closely related to the L1 through data on how adult French speakers learning L2 Spanish in a formal setting develop knowledge and use of past tenses in this L2. We consider the role of transfer and simplification in acquiring mental representations of the L2 grammar, specifically in the area of tense and aspect, and how learners deal with integrating grammatically encoded, lexical and discursive information, including mismatching feature combinations leading to particular inferential effects on interpretation. Data is presented on the Spanish past tenses (simple and compound past, pluperfect, imperfect and progressive forms from two tasks, an oral production filmretell and a multiple-choice interpretation task, completed by learners at A2, B1, B2 and C1 CEFR levels (N = 20-24 per level. L1 influence is progressively attenuated as proficiency increases. Difficulties were not always due to negative L1 transfer, but related also to grammar-discourse interface issues when integrating linguistic and pragmatic information in the interpretation process. This has clear implications for the teaching of closely related languages: instruction should not only focus on crosslinguistic contrasts, but also prioritize uses requiring complex interface integration, which are harder to process.

Bifunctional Derivative of p,p'-Dichlorochalcone. Part II. Synthesis of a Novel Compound 2-[2-Carboxymethylthio-2-(4-chlorophenylethyl]-2-(4-chlorophenyl-4-thiazolidinone

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Roger Dommisse

1999-07-01

Full Text Available The synthesis of 2-[2-carboxymethylthio-2-(4-chlorophenyl ethyl]-2-(4-chlorophenyl - 4-thiazolidinone (1 from p, p'- dichlorochalcone using thioglycollic acid in the presence of ammonium carbonate is described. Structural assignment and stereochemistry are discussed.

Becoming "Spanish Learners": Identity and Interaction among Multilingual Children in a Spanish-English Dual Language Classroom

Science.gov (United States)

Martínez, Ramón Antonio; Durán, Leah; Hikida, Michiko

2017-01-01

This article explores the interactional co-construction of identities among two first-grade students learning Spanish as a third language in a Spanish-English dual language classroom. Drawing on ethnographic and interactional data, the article focuses on a single interaction between these two "Spanish learners" and two of their…

An Investigation of Anglicized Spanish as a Communication Strategy in the Beginning Spanish Classroom

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Kobeck, Ashley Brianne

2013-01-01

Considering the recent increase in Spanish use in the United States, particularly as reflected in the media, beginning Spanish students are entering their classrooms with knowledge of phrases such as "hasta la vista" and "numero uno," regardless of their amount of previous formal Spanish study. The present research focuses on…

75 FR 82098 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Amendment No. 1 to...

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2010-12-29

... exclusive means of allocating and using trading symbols. Pursuant to that Plan, securities listed on the BX... Commission finds that allowing the automatic portability of a symbol in the event that an issuer transfers... 5210(a) and 5210(e). (b) The company must have a fully independent Audit Committee comprised of at...

Vowel reduction patterns of early Spanish- English bilinguals receiving continuous L1 and L2 input

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Byers Emily

2017-06-01

Full Text Available This study investigates the production of three morphophonetic variations of schwa in American English: the plural allomorph {-s} as in watches, the possessive allomorph {-s} as in Sasha’s, and word-finally as in Russia. The production of these three allomorphs were examined in Miami’s English monolingual and early Spanish-English bilingual populations. Our purpose was to determine how native-like early Spanish-English bilinguals′ spectral qualities and reduced vowel durations were compared to Miami English monolinguals during a reading task. Results indicate that early bilinguals′ reduced vowels followed the same overall pattern as monolinguals, but had different acoustic properties.

77 FR 29730 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change, as...

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2012-05-18

... requirements. (6) The books, records, premises, officers, agents, directors and employees of NOS as a facility of BX shall be deemed to be the books, records, premises, officers, agents, directors and employees... of orders are deemed to be violative of applicable pre-trade requirements under Rule 15c3-5, the...

Cultural notions in Spanish Dictionaries for Foreigners

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Luis Pablo-Núñez

2017-11-01

Full Text Available Although later than in English, Linguistics applied to the teaching of Spanish language has produced several didactic dictionaries for foreigners in the last two decades. This dictionaries include grammatical information in order to facilitate pronunciation, and morphological or syntactical comprehension; cultural notions, however, are more difficult to include because they go beyond the scope of the lexicon. Through the analysis of some terms related to folk music and gastronomy, we analyse the inclusion of Spanish and Latin American cultural notions in the three main dictionaries of Spanish for foreigners: the dictionary for the teaching of the Spanish language published by Vox-Alcalá University (Diccionario para la enseñanza de la lengua española, the Salamanca Dictionary (Diccionario Salamanca de la lengua española and the Spanish dictionary for foreigners of SM publishing house (Diccionario de español para extranjeros.

Development and initial validation of a computer-administered health literacy assessment in Spanish and English: FLIGHT/VIDAS

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Ownby RL

2013-08-01

Full Text Available Raymond L Ownby,1 Amarilis Acevedo,2 Drenna Waldrop-Valverde,3 Robin J Jacobs,1 Joshua Caballero,4 Rosemary Davenport,1 Ana-Maria Homs,1 Sara J Czaja,5 David Loewenstein51Department of Psychiatry and Behavioral Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA; 2Center for Psychological Studies, Nova Southeastern University, Fort Lauderdale, FL, USA; 3Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA; 4College of Pharmacy, Department of Pharmacy Practice, Nova Southeastern University, Fort Lauderdale, FL, USA; 5University of Miami Miller School of Medicine, Miami, FL, USAAbstract: Current measures of health literacy have been criticized on a number of grounds, including use of a limited range of content, development on small and atypical patient groups, and poor psychometric characteristics. In this paper, we report the development and preliminary validation of a new computer-administered and -scored health literacy measure addressing these limitations. Items in the measure reflect a wide range of content related to health promotion and maintenance as well as care for diseases. The development process has focused on creating a measure that will be useful in both Spanish and English, while not requiring substantial time for clinician training and individual administration and scoring. The items incorporate several formats, including questions based on brief videos, which allow for the assessment of listening comprehension and the skills related to obtaining information on the Internet. In this paper, we report the interim analyses detailing the initial development and pilot testing of the items (phase 1 of the project in groups of Spanish and English speakers. We then describe phase 2, which included a second round of testing of the items, in new groups of Spanish and English speakers, and evaluation of the new measure's reliability and validity in relation to other measures. Data are presented that show

Economic anglicisms: adaptation to the Spanish linguistic system

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Paloma López Zurita

2005-10-01

Full Text Available The enormous number of anglicisms used everyday in Spanish language generates lexical interference between both languages. This paper provides a semantic analysis of the changes in lexis this language contact brings about, through the different linguistic mechanisms of inter-language adaptation involved. When these anglicisms come from the current trend to include English words in Spanish discourse, we also add appropriate equivalents which could avoid the excess of redundant neologisms. A glossary of the most habitual terms derived from interference in English and Spanish in the economic field is included as a result of this study.

Responsiveness of the Spanish Version of the “Skin Cancer Index”

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M. de Troya-Martín

2016-01-01

Full Text Available Background. Skin Cancer Index (SCI is a specific questionnaire measuring health related quality of life (HRQL in patients with cervicofacial non-melanoma skin cancer (CFNMSC. The original scale has recently been adapted and validated into Spanish. Objectives. Evaluate the responsiveness of the Spanish version of SCI. Methods. Patients with CFNMSC candidate for surgical treatment were administered the questionnaire at time of diagnostic (t0, 7 days after surgery (t1, and 5 months after surgery (t2. The scale and subscales scores (C1: social/appearance, C2: emotional were then evaluated. Differences between t0-t1, t1-t2, and t0-t2 were determined and a gender-and-age segmented analysis was performed. Results. 88 patients, 54.8% male, mean age 62.5 years, completed the study. Differences between t0-t1 and t1-t2 scores were statistically significant (p<0.05. The lowest values were found at time of diagnosis and postsurgery. Women and patients under 65 years showed the lowest values at the three times. Limitations. Concrete geographic and cultural area. Clinical and histological variables are not analysed. Conclusions. Our results confirm responsiveness of the Spanish version of the SCI. Further development of the instrument in Spanish-speaking countries and populations will make it possible to extend worldwide research and knowledge horizons on skin cancer.

Teaching English-Spanish Cognates Using the Texas 2x2 Picture Book Reading Lists

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Montelongo, José A.; Hernández, Anita C.; Herter, Roberta J.

2015-01-01

English-Spanish cognates are words that possess identical or nearly identical spellings and meanings in both English and Spanish as a result of being derived mainly from Latin and Greek. Of major importance is the fact that many of the more than 20,000 cognates in English are academic vocabulary words, terms essential for comprehending school…

78 FR 62841 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To...

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2013-10-22

... million, shares of liquidity during the month, which is a higher rate than the base rate of $0.0007 per... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-70655; File No. SR-BX-2013-054] Self-Regulatory... Exchange Rule 7018(a) With Respect to Transactions in Securities Priced at $1 per Share or Greater October...

Does Spanish instruction for emergency medicine resident physicians improve patient satisfaction in the emergency department and adherence to medical recommendations?

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Stoneking LR

2016-08-01

Full Text Available LR Stoneking,1 AL Waterbrook,1 J Garst Orozco,2 D Johnston,1 A Bellafiore,1 C Davies,3 T Nuño,1 J Fatás-Cabeza,4 O Beita,5 V Ng,1 KH Grall,6 W Adamas-Rappaport7 1Department of Emergency Medicine, University of Arizona, Tucson, AZ, 2Department of Emergency Medicine, Sinai Health System, Chicago, IL, 3Department of Emergency Medicine, Maricopa Medical Center, Phoenix, AZ, 4Department of Spanish and Portuguese, University of Arizona, Tucson, AZ, 5Department of Family and Community Medicine, University of Arizona, Tucson, AZ, 6Department of Emergency Medicine, Regions Hospital, St Paul, MN, 7Department of Surgery, University of Arizona, Tucson, AZ, USA Background: After emergency department (ED discharge, Spanish-speaking patients with limited English proficiency are less likely than English-proficient patients to be adherent to medical recommendations and are more likely to be dissatisfied with their visit.Objectives: To determine if integrating a longitudinal medical Spanish and cultural competency curriculum into emergency medicine residency didactics improves patient satisfaction and adherence to medical recommendations in Spanish-speaking patients with limited English proficiency.Methods: Our ED has two Emergency Medicine Residency Programs, University Campus (UC and South Campus (SC. SC program incorporates a medical Spanish and cultural competency curriculum into their didactics. Real-time Spanish surveys were collected at SC ED on patients who self-identified as primarily Spanish-speaking during registration and who were treated by resident physicians from both residency programs. Surveys assessed whether the treating resident physician communicated in the patient’s native Spanish language. Follow-up phone calls assessed patient satisfaction and adherence to discharge instructions.Results: Sixty-three patients self-identified as primarily Spanish-speaking from August 2014 to July 2015 and were initially included in this pilot study

Spanish report to the framework convention of United Nations on the Climatic Change. Informe de Espana a la Convencion Marco de las Naciones UNidas sobre el cambio climatico

Energy Technology Data Exchange (ETDEWEB)

1994-01-01

This report has the following chapters: 1.- Synthesis of national report: main aspect of Spanish report. 2.- Reference frame: Spanish situation, the factors of risk, Spanish contribution to the CO[sub 2] emissions. 3.- Estimations of future climate. 4.- International engagements assumed by Spain. 5.- Evaluation and control of greenhouse gases

Globalisation, Tradition And Cultural Identity In Spanish Football

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Jim O'Brien

2016-12-01

Full Text Available This article offers some reflections and observations on the complex relationship between the forces of Globalisation and Spanish football, posing the key question as to whether the impact of Globalisation has been a quintessentially corrosive dynamic, eroding the quasi - sacrosanct traditions of the Spanish game to fashion a distinctive post- modern pastiche of elitism and inequality based on an orgy of consumption and commodity.

7 CFR 51.2731 - U.S. Spanish Splits.

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2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Spanish Splits. 51.2731 Section 51.2731... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2731 U.S. Spanish Splits. “U.S. Spanish Splits” consists of shelled Spanish type peanut kernels which are split or broken...

The Noticias de los arquitectos: towards a ‘National’ definition of Spanish architecture

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Miriam Cera

2016-06-01

Full Text Available The book Noticias de los arquitectos y arquitectura de España desde su Restauración is the first ever history of Spanish architecture published in Spain. The book´s writing was undertaken by scholar and politician Eugenio Llaguno, around 1769, with the aim of defending Spanish arts against harsh contemporary criticisms. However, it was not published until 1829, and was finished by a completely different scholar, Juan Agustín Ceán Bermúdez. Thus, it is chiefly important because it reflects the evolution of Spanish thought over this 60 year period, including the impact of the French invasion in 1808, which led to a search of a National identity in the architectural past.

Development of early numerical abilities of Spanish-speaking Mexican preschoolers: A new assessment tool.

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Beltrán-Navarro, Beatriz; Abreu-Mendoza, Roberto A; Matute, Esmeralda; Rosselli, Monica

2018-01-01

This article presents a tool for assessing the early numerical abilities of Spanish-speaking Mexican preschoolers. The Numerical Abilities Test, from the Evaluación Neuropsicológica Infantil-Preescolar (ENI-P), evaluates four core abilities of number development: magnitude comparison, counting, subitizing, and basic calculation. We evaluated 307 Spanish-speaking Mexican children aged 2 years 6 months to 4 years 11 months. Appropriate internal consistency and test-retest reliability were demonstrated. We also investigated the effect of age, children's school attendance, maternal education, and sex on children's numerical scores. The results showed that the four subtests captured development across ages. Critically, maternal education had an impact on children's performance in three out of the four subtests, but there was no effect associated with children's school attendance or sex. These results suggest that the Numerical Abilities Test is a reliable instrument for Spanish-speaking preschoolers. We discuss the implications of our outcomes for numerical development.

The reach of Spanish-language YouTube videos on physical examinations made by undergraduate medical students

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José M. Ramos-Rincón

2017-12-01

Full Text Available This study was conducted to evaluate the performance and reach of YouTube videos on physical examinations made by Spanish university students. We analyzed performance metrics for 4 videos on physical examinations in Spanish that were created by medical students at Miguel Hernández University (Elche, Spain and are available on YouTube, on the following topics: the head and neck (7:30, the cardiovascular system (7:38, the respiratory system (13:54, and the abdomen (11:10. We used the Analytics application offered by the YouTube platform to analyze the reach of the videos from the upload date (February 17, 2015 to July 28, 2017 (2 years, 5 months, and 11 days. The total number of views, length of watch-time, and the mean view duration for the 4 videos were, respectively: 164,403 views (mean, 41,101 views; range, 12,389 to 94,573 views, 425,888 minutes (mean, 106,472 minutes; range, 37,889 to 172,840 minutes, and 2:56 minutes (range, 1:49 to 4:03 minutes. Mexico was the most frequent playback location, followed by Spain, Colombia, and Venezuela. Uruguay, Ecuador, Mexico, and Puerto Rico had the most views per 100,000 population. Spanish-language tutorials are an alternative tool for teaching physical examination skills to students whose first language is not English. The videos were especially popular in Uruguay, Ecuador, and Mexico.

Satisfaction With Communication in Primary Care for Spanish-Speaking and English-Speaking Parents.

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Flower, Kori B; Skinner, Asheley C; Yin, H Shonna; Rothman, Russell L; Sanders, Lee M; Delamater, Alan; Perrin, Eliana M

Effective communication with primary care physicians is important yet incompletely understood for Spanish-speaking parents. We predicted lower satisfaction among Spanish-speaking compared to English-speaking Latino and non-Latino parents. Cross-sectional analysis at 2-month well visits within the Greenlight study at 4 pediatric resident clinics. Parents reported satisfaction with 14 physician communication items using the validated Communication Assessment Tool (CAT). High satisfaction was defined as "excellent" on each CAT item. Mean estimations compared satisfaction for communication items among Spanish- and English-speaking Latinos and non-Latinos. We used generalized linear regression modeling, adjusted for parent age, education, income, and clinic site. Among Spanish-speaking parents, we compared visits conducted in Spanish with and without an interpreter, and in English. Compared to English-speaking Latino (n = 127) and non-Latino parents (n = 432), fewer Spanish-speaking parents (n = 303) reported satisfaction with 14 communication items. No significant differences were found between English-speaking Latinos and non-Latinos. Greatest differences were found in the use of a greeting that made the parent comfortable (59.4% of Spanish-speaking Latinos endorsing "excellent" vs 77.5% English-speaking Latinos, P English-speaking Latinos, P < .01). After adjusting for parent age, education, income, and study site, Spanish-speaking Latinos were still less likely to report high satisfaction with these communication items. Satisfaction was not different among Spanish-speaking parents when the physician spoke Spanish versus used an interpreter. Satisfaction with physician communication was associated with language but not ethnicity. Spanish-speaking parents less frequently report satisfaction with communication, and innovative solutions to enhance communication quality are needed. Copyright © 2017 Academic Pediatric Association. Published by Elsevier Inc. All

Posthumous Tales of One, Great, Free Nation: Spanishness in post-Franco Spanish Film

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Martínez-Expósito, Alfredo

2008-11-01

Full Text Available An important form of transmission of knowledge about the Spanish nation is based on the continuous telling of stories in which the nation features as a suprahistorical, perennial entity. Myths of national origin, golden-age legends, and epics of national heroes are some of these stories. This mode of access to knowledge assumes a suspension of disbelief for the audience, and precludes other attempts to comprehend the nation through scientific research. Subjective national identities constructed upon such suspension of disbelief have a tendency to reify, personify or even deify the nation. In the struggle between mythic and objective knowledge, the question of authenticity becomes a hotly contested arena. This paper attempts to address questions of mythical national representation in Spanish films of 1975-2000.

The effectiveness of a mixed methodology implemented in a Beginner’s Spanish Course to develop the four language skills: a quasi-experimental study

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Kerwin Anthony Livingstone

2011-11-01

Full Text Available Normal 0 21 false false false ES X-NONE X-NONE MicrosoftInternetExplorer4 This present article seeks to provide a mixed methodological model for the development and implementation of a Teaching Module for Spanish as a Foreign Language in the face-to-face environment. The primary objective is to portray how methodological principles from different language teaching approaches (such as task based language teaching and cooperative learning can be combined effectively in designing activities for face-to-face contexts. In this regard, empirical evidence is analysed in order to determine the effectiveness of the mixed methodology in the teaching-learning of Spanish as a Foreign Language in the said settings, in a study based on a longitudinal experimental design with pre-test and post-test, but without control group. The results show an increase in the acquisition of specific knowledge in Spanish as a Foreign Language. It is therefore proposed that mixed methodological models be integrated and implemented when designing Teaching Modules for Language Learning, since they are the most suited for Second and Foreign Language Acquisition.

Recruiting pregnant smokers from Text4baby for a randomized controlled trial of Quit4baby.

Science.gov (United States)

Leavitt, Leah; Abroms, Lorien; Johnson, Pamela; Schindler-Ruwisch, Jennifer; Bushar, Jessica; Singh, Indira; Cleary, Sean D; McInvale, Whitney; Turner, Monique

2017-06-01

Recruiting pregnant smokers into clinical trials is challenging since this population tends to be disadvantaged, the behavior is stigmatized, and the intervention window is limited. The purpose of this study is to test the feasibility and effectiveness of recruiting pregnant smokers into a smoking cessation trial by sending recruitment text messages to an existing subscriber list. Recruitment messages were sent to subscribers flagged as pregnant in Text4baby, a national text messaging program for pregnant women and mothers. Four recruitment messages were rotated to test the effectiveness of different emotional frames and a financial incentive. Study staff called subscribers who expressed interest to screen for eligibility and enroll eligible women. Between October 6, 2015 and February 2, 2016, 10,194 recruitment messages were sent to Text4baby subscribers flagged as pregnant, and 10.18% (1038) responded indicating interest. No significant increase in cancellation was observed compared to subscribers who received other ad hoc messages. Of respondents, 54.05% (561) were reached by phone for follow-up, and 21.97% (228) were found to be eligible. Among the eligible, 87% (199) pregnant smokers enrolled. The recruitment message with a pride emotional appeal had a significantly higher response (p = 0.02) compared to the recruitment message with no emotional appeal, but enrollment did not significantly differ between recruitment messages with different emotional appeals. The recruitment messages with a reference to financial incentive yielded higher response (p < 0.01) and enrollment (p = 0.03) compared to a recruitment message without. This study demonstrates success recruiting pregnant smokers using text message. Future studies should consider building on this approach for recruiting high-risk populations.

A Case-based Reasoning Approach to Validate Grammatical Gender and Number Agreement in Spanish language

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Jorge Bacca

2013-03-01

Full Text Available Across Latin America 420 indigenous languages are spoken. Spanish is considered a second language in indigenous communities and is progressively introduced in education. However, most of the tools to support teaching processes of a second language have been developed for the most common languages such as English, French, German, Italian, etc. As a result, only a small amount of learning objects and authoring tools have been developed for indigenous people considering the specific needs of their population. This paper introduces Multilingual–Tiny as a web authoring tool to support the virtual experience of indigenous students and teachers when they are creating learning objects in indigenous languages or in Spanish language, in particular, when they have to deal with the grammatical structures of Spanish. Multilingual–Tiny has a module based on the Case-based Reasoning technique to provide recommendations in real time when teachers and students write texts in Spanish. An experiment was performed in order to compare some local similarity functions to retrieve cases from the case library taking into account the grammatical structures. As a result we found the similarity function with the best performance

Spanish I

CERN Document Server

Rodriguez, Jill

2001-01-01

CliffsQuickReview course guides cover the essentials of your toughest classes. Get a firm grip on core concepts and key material, and test your newfound knowledge with review questions. CliffsQuickReview Spanish I is meant to provide all the foundations of basic Spanish pronunciation, spelling, and sentence construction. Spanish grammar is systematically explained in its most simplistic way, so there's no need for any prerequisite before beginning this ""review"" of the equivalent of two years of high school Spanish. As you work your way through this review, you'll be ready to tackle such conc

A budget impact analysis of Spiromax® compared with Turbuhaler® for the treatment of moderate to severe asthma: a potential improvement in the inhalation technique to strengthen medication adherence could represent savings for the Spanish Healthcare System and five Spanish regions

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Darbà J

2016-09-01

Full Text Available Josep Darbà,1 Gabriela Ramírez,2 Juan L García-Rivero,3 Sagrario Mayoralas-Alises,4 José Francisco Pascual,5 Albert Roger,6 Diego Vargas,7 Adi Bijedic8 1Department of Economics, Universitat de Barcelona, 2BCN Health Economics & Outcomes Research SL, 3Hospital Laredo, Cantabria, 4Hospital Ramón y Cajal, Madrid, 5Hospital General Universitario de Alicante, Alicante, 6Hospital Universitario Germans Trias i Pujol, Barcelona, 7Hospital de Alta Resolución el Toyo, Andalusia, 8Market Access and HEOR Department, TEVA Pharmaceutical, Madrid, Spain Objective: To assess the economic impact of the introduction of DuoResp® Spiromax® by focusing on a potential improvement in the inhalation technique to strengthen medication adherence for the treatment of moderate to severe asthmatics in Spain and five Spanish regions including Andalusia, Catalonia, Galicia, Madrid, and Valencia.Methods: A 4-year budget impact model was developed for the period 2015–2018 from the Spanish Healthcare System perspective. Budesonide–formoterol fixed-dose combination delivered by Turbuhaler® was considered to be the most appropriate comparator for assessing the budget impact with the introduction of DuoResp® Spiromax®. National and regional data on asthma prevalence were obtained from the literature. Input parameters on health care resources were obtained by consulting experts from different Spanish hospitals. Resources used included medical visits, emergency room visits, and hospitalizations. The average numbers of primary care and specialist visits per year were also gathered. Based on health care resource use per patient, the total treatment cost per patient was estimated.Results: The population with moderate to severe asthma treated with budesonide–formoterol fixed-dose combinations delivered by Turbuhaler® in 2015 was estimated to be 166,985 in Spain. Region-specific prevalence data resulted in 25,081, 12,392, 16,097, 17,829, and 15,148 patients in Andalusia

Analysis of Dietary Pattern Impact on Weight Status for Personalised Nutrition through On-Line Advice: The Food4Me Spanish Cohort.

Science.gov (United States)

San-Cristobal, Rodrigo; Navas-Carretero, Santiago; Celis-Morales, Carlos; Brennan, Lorraine; Walsh, Marianne; Lovegrove, Julie A; Daniel, Hannelore; Saris, Wim H M; Traczyk, Iwonna; Manios, Yannis; Gibney, Eileen R; Gibney, Michael J; Mathers, John C; Martinez, J Alfredo

2015-11-17

Obesity prevalence is increasing. The management of this condition requires a detailed analysis of the global risk factors in order to develop personalised advice. This study is aimed to identify current dietary patterns and habits in Spanish population interested in personalised nutrition and investigate associations with weight status. Self-reported dietary and anthropometrical data from the Spanish participants in the Food4Me study, were used in a multidimensional exploratory analysis to define specific dietary profiles. Two opposing factors were obtained according to food groups' intake: Factor 1 characterised by a more frequent consumption of traditionally considered unhealthy foods; and Factor 2, where the consumption of "Mediterranean diet" foods was prevalent. Factor 1 showed a direct relationship with BMI (β = 0.226; r² = 0.259; p dietary patterns, which were characterized by high-density foods consumption, showed positive associations with overweight prevalence. Further analysis showed that prevention of overweight must focus on limiting the intake of known deleterious foods rather than exclusively enhance healthy products.

Knowledge in palliative care of nursing professionals at a Spanish hospital

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Elena Chover-Sierra

2017-10-01

Full Text Available Resume Objective: to determine the level of knowledge in palliative care of nursing staff at a Spanish tertiary care hospital. Method: descriptive, cross-sectional study. Data were collected about the results of the Spanish version of the Palliative Care Quiz for Nurses (PCQN, sociodemographic aspects, education level and experience in the field of palliative care. Univariate and bivariate descriptive analysis was applied. Statistical significance was set at p < 0.05 in all cases. Results: 159 professionals participated (mean age 39.51 years ± 10.25, with 13.96 years ± 10.79 of professional experience 54.7% possessed experience in palliative care and 64.2% educational background (mainly basic education. The mean percentage of hits on the quiz was 54%, with statistically significant differences in function of the participants’ education and experience in palliative care. Conclusions: although the participants show sufficient knowledge on palliative care, they would benefit from a specific training program, in function of the mistaken concepts identified through the quiz, which showed to be a useful tool to diagnose professionals’ educational needs in palliative care.

The Impact of a Systematic and Explicit Vocabulary Intervention in Spanish with Spanish-Speaking English Learners in First Grade

Science.gov (United States)

Cena, Johanna; Baker, Doris Luft; Kame'enui, Edward J.; Baker, Scott K.; Park, Yonghan; Smolkowski, Keith

2013-01-01

This study examined the impact of a 15-min daily explicit vocabulary intervention in Spanish on expressive and receptive vocabulary knowledge and oral reading fluency in Spanish, and on language proficiency in English. Fifty Spanish-speaking English learners who received 90 min of Spanish reading instruction in an early transition model were…

En torno a las adaptaciones del texto literario en el aula de ELE /About adaptations of literary texts in the Spanish as a foreign language classroom

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Francisco Jiménez Calderón

2013-09-01

Full Text Available Resumen: El objetivo de este artículo es unificar algunos criterios acerca de la utilización de textos literarios en el aula de español como lengua extranjera (ELE, sobre todo en relación con la adaptación de los textos. Para ello, se elabora una propuesta didáctica que consiste en una adaptación de El burlador de Sevilla, que ha sido trabajada en el aula de manera efectiva mediante actividades específicas. La conclusión es que el trabajo con textos literarios puede ser más rentable si se elabora una unidad didáctica basada en el texto aplicando el enfoque por tareas que normalmente se emplea en el método comunicativo. Además, el sentido del texto debe considerarse como el primer objetivo de aprendizaje.Abstract: The aim of this paper is to unify some criteria on the use of literary texts in the classroom of Spanish as a foreign language, especially in relation to the adaptation of the texts. For that, we develop a teaching proposal that is an adaptation of El burlador de Sevilla, which has been tested in the classroom effectively through specific activities. The conclusion is that working with literary texts can be more productive if we develop a teaching unit based on the text using the task-based approach normally used in the communicative approach. Besides, the sense of the text should be established as the most important learning objective.

78 FR 17255 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change to...

Science.gov (United States)

2013-03-20

.... First, SEC Rule 15c3-5 requires that, ``financial risk management controls and supervisory procedures... Subparagraph (d)(iv) Regarding Obvious Error or Catastrophic Error Review March 15, 2013. Pursuant to Section... provide for how BX proposes to treat options errors in response to the Regulation NMS Plan to Address...

Synthesis of (E-2,4-Dinitro-N-((2E,4E-4-phenyl-5-(pyrrolidin-1-ylpenta-2,4-dienylideneaniline

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Mostafa Fesanghari

2009-07-01

Full Text Available (E-2,4-Dinitro-N-((2E,4E-4-phenyl-5-(pyrrolidin-1-ylpenta-2,4-dienylidene aniline dye was prepared in one pot by reaction of premade N-2,4-dinitrophenyl-3-phenylpyridinium chloride (DNPPC and pyrrolidine in absolute MeOH.

Age of acquisition and allophony in Spanish-English bilinguals

Science.gov (United States)

Barlow, Jessica A.

2014-01-01

This study examines age of acquisition (AoA) in Spanish-English bilinguals’ phonetic and phonological knowledge of /l/ in English and Spanish. In English, the lateral approximant /l/ varies in darkness by context [based on the second formant (F2) and the difference between F2 and the first formant (F1)], but the Spanish /l/ does not. Further, English /l/ is overall darker than Spanish /l/. Thirty-eight college-aged adults participated: 11 Early Spanish-English bilinguals who learned English before the age of 5 years, 14 Late Spanish-English bilinguals who learned English after the age of 6 years, and 13 English monolinguals. Participants’ /l/ productions were acoustically analyzed by language and context. The results revealed a Spanish-to-English phonetic influence on /l/ productions for both Early and Late bilinguals, as well as an English-to-Spanish phonological influence on the patterning of /l/ for the Late Bilinguals. These findings are discussed in terms of the Speech Learning Model and the effect of AoA on the interaction between a bilingual speaker’s two languages. PMID:24795664

Genetic diversity in Spanish donkey breeds using microsatellite DNA markers

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Jordana Jordi

2001-07-01

Full Text Available Abstract Genetic diversity at 13 equine microsatellite loci was compared in five endangered Spanish donkey breeds: Andaluza, Catalana, Mallorquina, Encartaciones and Zamorano-Leonesa. All of the equine microsatellites used in this study were amplified and were polymorphic in the domestic donkey breeds with the exception of HMS1, which was monomorphic, and ASB2, which failed to amplify. Allele number, frequency distributions and mean heterozygosities were very similar among the Spanish donkey breeds. The unbiased expected heterozygosity (HE over all the populations varied between 0.637 and 0.684 in this study. The low GST value showed that only 3.6% of the diversity was between breeds (P A distance matrix showed little differentiation between Spanish breeds, but great differentiation between them and the Moroccan ass and also with the horse, used as an outgroup. These results confirm the potential use of equine microsatellite loci as a tool for genetic studies in domestic donkey populations, which could also be useful for conservation plans.

Differences between Spanish monolingual and Spanish-English bilingual children in their calculation of entailment-based scalar implicatures

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Kristen Syrett

2017-04-01

Full Text Available In this paper, we extend investigations of the possible effects of cross-linguistic influence at the pragmatics-syntax interface (Hulk & Müller 2000; Müller & Hulk 2001; Serratrice, Sorace & Paoli 2004, by presenting two experiments designed to probe how Spanish monolingual and Spanish-English bilingual preschool-age children approach the ‘some, but not all’ 'scalar implicature '(SI associated with 'algunos '(‘some’. We compare 'algunos 'and 'unos '(also a ‘some’ indefinite, but one that is not context-linked and does not induce an SI, and 'algunos 'and 'todos '(the universal quantifier ‘every/all’. The performance of the children is compared to fluent adult Spanish heritage speakers. Experiment 1 is a variation of Noveck’s (2001 statement evaluation task, also replicated by Guasti et al'. '(2005. Experiment 2 is a forced-choice picture selection task. Results demonstrate that adults were the only group to consistently calculate the SI associated with 'algunos '– a finding that was expected to some extent, given that our tasks were stripped of the contextual support that could benefit children’s pragmatic reasoning. While bilingual and monolingual children displayed comparable performance across tasks, bilinguals in Experiment 2 appeared to experience difficulty with judgments related to 'todos '– a pattern we attribute (in light of independent findings to the cognitive overload in the task, not the lexical entry of this quantifier. We conclude that young monolingual and bilingual children confront the same challenges when called upon to deploy pragmatic skills in a discourse context. This article is part of the special collection:Acquisition of Quantification

ENTREVIS - a Spanish machine-readable text corpus

DEFF Research Database (Denmark)

Jensen, Kjær

1991-01-01

Præsentation af første halvdel et spansk tekskorpus bestående af samtlige interviews med spaniere i de to ugeskrifter Cambio16 og Tiempo i 1990. Dette korpus er siden suppleret med samtlige interviews i de samme tidsskrifter i 1995. Korpus samlede størrelse: over 1.2 million ord...

Extremely Energetic 4B/X17.2 Flare and Associated Phenomena ...

Indian Academy of Sciences (India)

Aryabhatta Research Institute of Observational Sciences (ARIES), Manora Peak,. Nainital 263 129 ... In this paper, we present the preliminary analysis of X17.2 flare, observed on. 28 October 2003. ... The Hα movie shows large scale .... we calculate the thermal energy (Eth) content of the flare applying the following formula:.

Spanish Is Foreign: Heritage Speakers' Interpretations of the Introductory Spanish Language Curriculum

Science.gov (United States)

DeFeo, Dayna Jean

2015-01-01

This article presents a case study of the perceptions of Spanish heritage speakers enrolled in introductory-level Spanish foreign language courses. Despite their own identities that were linked to the United States and Spanish of the Borderlands, the participants felt that the curriculum acknowledged the Spanish of Spain and foreign countries but…

Medical Spanish in U.S. Colleges and Schools of Pharmacy

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Geoffrey A Mospan

2016-09-01

Full Text Available Objective: To determine characteristics of Medical Spanish education provided to pharmacy students in schools and colleges of pharmacy in the United States. Methods: A survey of U.S. pharmacy schools and colleges was performed to determine availability of Medical Spanish in pharmacy curriculum, course(s containing Medical Spanish education, and characteristics of Medical Spanish courses. Additional follow-up questions were asked if a school did not offer Medical Spanish. Results: 61 out of 138 institutions completed the survey (response rate = 44%. 36% (22/61 of respondents reported Medical Spanish education was offered in their curriculum. The most common barrier to offering a Medical Spanish course included a lack of personnel to teach the course (n=21, 54% or no room in the curriculum (n=15, 38%. Conclusion: While there is a limited number of institutions that provide Medical Spanish education to their pharmacy students, results of this survey provide a basic description of Medical Spanish education in schools and colleges of pharmacy in the United States. Data obtained from this survey can be used to refine or initiate Medical Spanish courses, including the teaching and assessment methods used. Conflict of Interest We declare no conflicts of interest or financial interests that the authors or members of their immediate families have in any product or service discussed in the manuscript, including grants (pending or received, employment, gifts, stock holdings or options, honoraria, consultancies, expert testimony, patents and royalties   Type: Original Research

1-(4a,8-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl-3-(4-methylphenylprop-2-en-1-one

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Mohamed Tebbaa

2011-06-01

Full Text Available The title compound, C22H28O, was isolated from the aerial part of Inula viscosa (L Aiton [or Dittrichia viscosa (L Greuter]. The cyclohexene ring has a half-chair conformation, whereas the cyclohexane ring displays a chair conformation being substituted at position 2 by a 3-(4-methylphenylprop-2-enoyl group. In the crystal, weak intermolecular C—H...O hydrogen bonds link molecules into chains in the [010] direction.

Crucial times for Spanish physical oceanography

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Josep L. Pelegrí

2012-08-01

Full Text Available The field of physical oceanography has undergone exponential growth in Spain during the last few decades. From a handful of self-taught researchers in the late 1960s there are now several hundred physical oceanographers distributed in some 20 Spanish institutions, and many more working overseas. The First Spanish Physical Oceanography Meeting (EOF1, held in Barcelona in October 2010, was a good example of the high quality and large variety of this research. The facilities and human resources are excellent but the alarming decrease in public investment in science due to the economic crisis must lead the Spanish physical oceanography community to define its current priorities. In this introductory paper to EOF1 we revise our history and where we are now, and suggest that progress in the near future will rely on our intelligence to sustain and enhance human capital, partnership and society-oriented research.

Prevention of Adolescent Depression in the Spanish-Speaking World

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Andrea B. Horn

2014-05-01

Full Text Available This paper aims at presenting programs targeted at the prevention of adolescent depression applied with Spanish-speaking populations that have been developed in Spanish-speaking countries and are mostly published in Spanish. These programs have been developed under different cultural contexts in Spain and Latin-America. The main goal of this paper is to make the studies and movements of the Spanish-speaking literature in this field accessible to the non-Spanish-speaking part of the research community. Therefore, after an introduction referring to possible cultural differences regarding depression in general and epidemiological basics, several programs are introduced. In total 11 programs will be shortly presented and discussed. After revising the programs it can be concluded that in the Spanish-speaking world many programs have been developed and conducted following current state of the art-approaches for adolescent depression prevention. Further research is needed especially targeting possible cultural and contextual aspects of prevention measures and their efficacy and efficiency.

Cultural adaptation into Spanish of the generalized anxiety disorder-7 (GAD-7 scale as a screening tool

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Pérez-Páramo María

2010-01-01

Full Text Available Abstract Background Generalized anxiety disorder (GAD is a prevalent mental health condition which is underestimated worldwide. This study carried out the cultural adaptation into Spanish of the 7-item self-administered GAD-7 scale, which is used to identify probable patients with GAD. Methods The adaptation was performed by an expert panel using a conceptual equivalence process, including forward and backward translations in duplicate. Content validity was assessed by interrater agreement. Criteria validity was explored using ROC curve analysis, and sensitivity, specificity, predictive positive value and negative value for different cut-off values were determined. Concurrent validity was also explored using the HAM-A, HADS, and WHO-DAS-II scales. Results The study sample consisted of 212 subjects (106 patients with GAD with a mean age of 50.38 years (SD = 16.76. Average completion time was 2'30''. No items of the scale were left blank. Floor and ceiling effects were negligible. No patients with GAD had to be assisted to fill in the questionnaire. The scale was shown to be one-dimensional through factor analysis (explained variance = 72%. A cut-off point of 10 showed adequate values of sensitivity (86.8% and specificity (93.4%, with AUC being statistically significant [AUC = 0.957-0.985; p 0.001. Limitations Elderly people, particularly those very old, may need some help to complete the scale. Conclusion After the cultural adaptation process, a Spanish version of the GAD-7 scale was obtained. The validity of its content and the relevance and adequacy of items in the Spanish cultural context were confirmed.

‘Spanish Atlanteans’: Crisis of Empire and reconstruction of Spanish Monarchy (1672-1740

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Fernández Albaladejo, Pablo

2015-12-01

Full Text Available As a result of a internal crisis, the Spanish Monarchy underwent a process of redefinition between the end of the seventeenth century and the decade of the 1740s. By synthesizing traditional Spanish historiography with the insights of an incipient brand of European modernity, Spanish authors crafted a peculiar account of the “unknown past” of their body politic. The Spanish atlántidas rose to become creators of a great empire and protagonists in the founding of European culture. A new national imaginary emerged that legitimized the task of redefinition. With variations, this concern with origins dominated Spain’s introspection in the eighteenth century.Afectada por una profunda crisis interna, la Monarquía de España experimentó un proceso de redefinición identitaria entre el último tercio del siglo XVII y los años cuarenta del siglo XVIII. En una particular síntesis entre la tradición historiográfica propia y las propuestas que llegaban desde la incipiente modernidad europea, los autores de ese proceso configuraron un primer relato del “tiempo desconocido” de ese cuerpo político. Los atlántidas españoles irrumpieron como protagonistas de un renovado imaginario nacional, como un pueblo instituyente de la cultura europea y creador a la vez de un imperio grandioso que legitimaba la propia tarea de reconstrucción. Con variantes, esa preocupación por los orígenes dominaría la reflexión del siglo XVIII.

Text 2 Mind Map

OpenAIRE

Iona, John

2017-01-01

This is a review of the web resource 'Text 2 Mind Map' www.Text2MindMap.com. It covers what the resource is, and how it might be used in Library and education context, in particular for School Librarians.

Text Message Support for Weight Loss in Patients With Prediabetes: A Randomized Clinical Trial.

Science.gov (United States)

Fischer, Henry H; Fischer, Ilana P; Pereira, Rocio I; Furniss, Anna L; Rozwadowski, Jeanne M; Moore, Susan L; Durfee, Michael J; Raghunath, Silvia G; Tsai, Adam G; Havranek, Edward P

2016-08-01

Although the benefits of in-person Diabetes Prevention Program (DPP) classes for diabetes prevention have been demonstrated in trials, effectiveness in clinical practice is limited by low participation rates. This study explores whether text message support enhances weight loss in patients offered DPP classes. English- and Spanish-speaking patients with prediabetes (n = 163) were randomized to the control group, which only received an invitation to DPP classes as defined by the Centers for Disease Control and Prevention, or to the text message-augmented intervention group, which also received text messages adapted from the DPP curriculum for 12 months. Mean weight decreased 0.6 pounds (95% CI -2.7 to 1.6) in the control group and 2.6 pounds (95% CI -5.5 to 0.2) in the intervention group (P value 0.05). Three percent weight loss was achieved by 21.5% of participants in the control group (95% CI 12.5-30.6), compared with 38.5% in the intervention group (95% CI 27.7-49.3) (absolute difference 17.0%; P value 0.02). Mean glycated hemoglobin (HbA1c) increased by 0.19% or 2.1 mmol/mol (95% CI -0.1 to 0.5%) and decreased by 0.09% or 1.0 mmol/mol (95% CI -0.2 to 0.0%) in the control group and intervention participants, respectively (absolute difference 0.28%; P value 0.07). Stratification by language demonstrated a significant treatment effect in Spanish speakers but not in English speakers. Text message support can lead to clinically significant weight loss in patients with prediabetes. Further study assessing effect by primary language and in an operational setting is warranted. © 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Religious orientation and psychological well-being among Spanish undergraduates

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Joaquín García-Alandete

2013-06-01

Full Text Available This paper analyzes the relationship between intrinsic/extrinsic/quest religious orientation and psychological well-being in a sample of 180 Spanish undergraduates, 138 women (76.7% and 42 men (23.3%, aged 18-55, M = 22.91, sD = 6.71. Spanish adaptations of the Batson and Ventis´ Religious Orientation Scaleand the Ryff´s psychological Well-Being Scales were used to this aim. The results of a multiple regression analysis showed (1 a positive relationship between the intrinsic orientation and the psychological well-being measures except for Autonomy, (2 a negative relationship between the extrinsic orientation and Autonomy, and (3 a negative relationship between the quest orientation, Self-acceptance and Purpose in life. The results are discussed in the light of previous researches.

Perception of the Varieties of Spanish by Students of Spanish Language and Literature at the University of Zagreb

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Maša Musulin

2016-12-01

Full Text Available In 2016 a survey was carried out among students of Spanish Language and Literature at the University of Zagreb. The survey consisted of two parts and in this work we present the data obtained by the questionnaire, in which the students’ sociolinguistic knowledge of the Spanish language and its varieties was ascertained. The questionnaire was completed anonymously and voluntarily by 154 participants. The results showed that the Zagreb students recognize, among all the varieties of Spanish, the one from Madrid as the representative and the most identifiable, which can be explained by the fact that Spain is a European country and, therefore, much more accessible for Croatian students but also because of the influence of the RAE and its lexicographical works that predominate in the teaching of Spanish. A certain percentage of the questioned students believe that there is a less correct variety of Peninsular Spanish – Andalusian. The results also show the influence not only of the linguistic knowledge obtained during studies but furthermore the attitudes towards certain varieties. It is noted that Croatian students acquire not only the language but also sometimes the attitudes and stereotypes that generally exist among Spaniards. That means that the attitudes towards certain varieties are not necessary the result of their own evaluation but the stereotypes reflected by the greater contact with Spain and Spaniards.

Child custody assessment: a field survey of spanish forensic psychologists’ practices

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Joan Guàrdia

2011-07-01

Full Text Available The participation of forensic psychologists has become common practice in proceedings involving families in dispute over child custody, and also to assess the suitability of joint custody. In order to know the practice, methodology, and decision-making criteria of Spanish forensic psychologists experienced in family cases, 66 Spanish forensic psychologists (error margin ±.06 responded to a Spanish adaptation of the questionnaire for the assessment of child custody evaluation practices by Keilin and Bloom (1986 and Ackerman and Ackerman (1997. The results showed that it was indifferent for the respondents to be retained by the court or one of the parties, and that the evaluation included a document review, each parent’s individual interview, each child’s individual interview, psychological tests run to parents and children, observation of parent-child interaction, and reports by other professionals. As regards the custody type, most of them chose sole custody. As for decision-making criteria for sole custody, the results showed that Spanish forensic psychologists follow a hierarchical decision-making model that begins, firstly, with the application of criteria concerning the child’s protection (e.g. cruelty, abuse, negligence, then moving on to parental abilities. The decision over joint custody also follows a hierarchical decision-making model, where suitability is assessed initially and, if applicable, a decision is made based on its possible success or failure.

Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation

International Nuclear Information System (INIS)

Fujita, Mayumi; Imadome, Kaori; Shoji, Yoshimi; Isozaki, Tetsurou; Endo, Satoshi; Yamada, Shigeru; Imai, Takashi

2015-01-01

Purpose: To investigate the mechanisms underlying the inhibition of cancer cell migration and invasion by carbon (C)-ion irradiation. Methods and Materials: Human pancreatic cancer cells MIAPaCa-2, AsPC-1, and BxPC-3 were treated by x-ray (4 Gy) or C-ion (0.5, 1, 2, or 4 Gy) irradiation, and their migration and invasion were assessed 2 days later. The levels of guanosine triphosphate (GTP)-bound Rac1 and RhoA were determined by the active GTPase pull-down assay with or without a proteasome inhibitor, and the binding of E3 ubiquitin ligase to GTP-bound Rac1 was examined by immunoprecipitation. Results: Carbon-ion irradiation reduced the levels of GTP-bound Rac1 and RhoA, 2 major regulators of cell motility, in MIAPaCa-2 cells and GTP-bound Rac1 in AsPC-1 and BxPC-3 cells. Proteasome inhibition reversed the effect, indicating that C-ion irradiation induced Rac1 and RhoA degradation via the ubiquitin (Ub)-proteasome pathway. E3 Ub ligase X-linked inhibitor of apoptosis protein (XIAP), which directly targets Rac1, was selectively induced in C-ion–irradiated MIAPaCa-2 cells and coprecipitated with GTP-bound Rac1 in C-ion–irradiated cells, which was associated with Rac1 ubiquitination. Cell migration and invasion reduced by C-ion radiation were restored by short interfering RNA–mediated XIAP knockdown, indicating that XIAP is involved in C-ion–induced inhibition of cell motility. Conclusion: In contrast to x-ray irradiation, C-ion treatment inhibited the activity of Rac1 and RhoA in MIAPaCa-2 cells and Rac1 in AsPC-1 and BxPC-3 cells via Ub-mediated proteasomal degradation, thereby blocking the motility of these pancreatic cancer cells

Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation

Energy Technology Data Exchange (ETDEWEB)

Fujita, Mayumi; Imadome, Kaori; Shoji, Yoshimi [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan); Isozaki, Tetsurou; Endo, Satoshi; Yamada, Shigeru [Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan); Imai, Takashi, E-mail: imait@nirs.go.jp [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan)

2015-09-01

Purpose: To investigate the mechanisms underlying the inhibition of cancer cell migration and invasion by carbon (C)-ion irradiation. Methods and Materials: Human pancreatic cancer cells MIAPaCa-2, AsPC-1, and BxPC-3 were treated by x-ray (4 Gy) or C-ion (0.5, 1, 2, or 4 Gy) irradiation, and their migration and invasion were assessed 2 days later. The levels of guanosine triphosphate (GTP)-bound Rac1 and RhoA were determined by the active GTPase pull-down assay with or without a proteasome inhibitor, and the binding of E3 ubiquitin ligase to GTP-bound Rac1 was examined by immunoprecipitation. Results: Carbon-ion irradiation reduced the levels of GTP-bound Rac1 and RhoA, 2 major regulators of cell motility, in MIAPaCa-2 cells and GTP-bound Rac1 in AsPC-1 and BxPC-3 cells. Proteasome inhibition reversed the effect, indicating that C-ion irradiation induced Rac1 and RhoA degradation via the ubiquitin (Ub)-proteasome pathway. E3 Ub ligase X-linked inhibitor of apoptosis protein (XIAP), which directly targets Rac1, was selectively induced in C-ion–irradiated MIAPaCa-2 cells and coprecipitated with GTP-bound Rac1 in C-ion–irradiated cells, which was associated with Rac1 ubiquitination. Cell migration and invasion reduced by C-ion radiation were restored by short interfering RNA–mediated XIAP knockdown, indicating that XIAP is involved in C-ion–induced inhibition of cell motility. Conclusion: In contrast to x-ray irradiation, C-ion treatment inhibited the activity of Rac1 and RhoA in MIAPaCa-2 cells and Rac1 in AsPC-1 and BxPC-3 cells via Ub-mediated proteasomal degradation, thereby blocking the motility of these pancreatic cancer cells.

Data of evolutionary structure change: 2OZ2A-4PADA [Confc[Archive

Lifescience Database Archive (English)

Full Text Available 2OZ2A-4PADA 2OZ2 4PAD A A APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWF.../entryChain> 4PAD A 4PADA...n> 4PAD A 4PADA VVLQ...4PAD A 4PADA RIKRGTGNSYGVCG A 4PADA LVAQY---GIHYR

Language Growth in English Monolingual and Spanish-English Bilingual Children from 2.5 to 5 Years.

Science.gov (United States)

Hoff, Erika; Ribot, Krystal M

2017-11-01

To describe the trajectories of English and Spanish language growth in typically developing children from bilingual homes and compare those with the trajectories of English growth in children from monolingual homes, to assess effects of dual language exposure on language growth in typically developing children. Expressive vocabularies were assessed at 6-month intervals from age 30 to 60 months, in English for monolinguals and English and Spanish for bilinguals. Use of English and Spanish in the home was assessed via parental report. Multilevel modeling, including parent education as a covariate, revealed that children from bilingual homes lagged 6 months to 1 year behind monolingual children in English vocabulary growth. The size of the lag was related to the relative amount of English use in the home, but the relation was not linear. Increments in English use conferred the greatest benefit most among homes with already high levels of English use. These homes also were likely to have 1 parent who was a native English speaker. Bilingual children showed stronger growth in English than in Spanish. Bilingual children can lag 6 months to 1 year behind monolingual children in normal English language development. Such lags may not necessarily signify clinically relevant delay if parents report that children also have skills in the home language. Shorter lags are associated with 2 correlated factors: more English exposure and more exposure from native English speakers. Early exposure to Spanish in the home does not guarantee acquisition of Spanish. Copyright © 2017 Elsevier Inc. All rights reserved.

The Presence of Spanish and Hispanic American Literature in Slovenian secondary Schools since 1945

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Marjana Šifrar Kalan

2017-12-01

Full Text Available Traditionally Slovene secondary schools teach national and international literature as part of the study of Slovene. The article examines the presence and the selection of Spanish and Hispanic American literature in Slovene secondary schools between 1945 and 2017, taking into account sociopolitical, cultural and didactic factors. The analysis is based on all syllabuses for Slovene during this period and all text books for literature used and edited since the end of the second world war in Slovenia. Therefore the role of literature written in Spanish is analysed for two different sociopolitical contexts: Yugoslavia and the independent Republic of Slovenia. The aim of the article is to find out whether the presence and the role of Spanish language literature in Spanish has increased or decreased during this period and which are the authors and literary works which 19-year-old Slovenes who complete grammar school and continue their studies at the university are/were acquainted with. The article enumerates all writers and texts in Spanish from the analysed documents and textbooks, identifies drawbacks in the selection of the literature and concludes that experts from different fields, teachers of Slovene, Spanish, experts in literature and didactics should work on a well-balanced selection of Spanish and Hispanic American literature within the teaching of world literature.

Outcome of ABCA4 disease-associated alleles in autosomal recessive retinal dystrophies: retrospective analysis in 420 Spanish families.

Science.gov (United States)

Riveiro-Alvarez, Rosa; Lopez-Martinez, Miguel-Angel; Zernant, Jana; Aguirre-Lamban, Jana; Cantalapiedra, Diego; Avila-Fernandez, Almudena; Gimenez, Ascension; Lopez-Molina, Maria-Isabel; Garcia-Sandoval, Blanca; Blanco-Kelly, Fiona; Corton, Marta; Tatu, Sorina; Fernandez-San Jose, Patricia; Trujillo-Tiebas, Maria-Jose; Ramos, Carmen; Allikmets, Rando; Ayuso, Carmen

2013-11-01

To provide a comprehensive overview of all detected mutations in the ABCA4 gene in Spanish families with autosomal recessive retinal disorders, including Stargardt's disease (arSTGD), cone-rod dystrophy (arCRD), and retinitis pigmentosa (arRP), and to assess genotype-phenotype correlation and disease progression in 10 years by considering the type of variants and age at onset. Case series. A total of 420 unrelated Spanish families: 259 arSTGD, 86 arCRD, and 75 arRP. Spanish families were analyzed through a combination of ABCR400 genotyping microarray, denaturing high-performance liquid chromatography, and high-resolution melting scanning. Direct sequencing was used as a confirmation technique for the identified variants. Screening by multiple ligation probe analysis was used to detect possible large deletions or insertions in the ABCA4 gene. Selected families were analyzed further by next generation sequencing. DNA sequence variants, mutation detection rates, haplotypes, age at onset, central or peripheral vision loss, and night blindness. Overall, we detected 70.5% and 36.6% of all expected ABCA4 mutations in arSTGD and arCRD patient cohorts, respectively. In the fraction of the cohort where the ABCA4 gene was sequenced completely, the detection rates reached 73.6% for arSTGD and 66.7% for arCRD. However, the frequency of possibly pathogenic ABCA4 alleles in arRP families was only slightly higher than that in the general population. Moreover, in some families, mutations in other known arRP genes segregated with the disease phenotype. An increasing understanding of causal ABCA4 alleles in arSTGD and arCRD facilitates disease diagnosis and prognosis and also is paramount in selecting patients for emerging clinical trials of therapeutic interventions. Because ABCA4-associated diseases are evolving retinal dystrophies, assessment of age at onset, accurate clinical diagnosis, and genetic testing are crucial. We suggest that ABCA4 mutations may be associated with a

Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.

Science.gov (United States)

Tavera-Tapia, A; Pérez-Cabornero, L; Macías, J A; Ceballos, M I; Roncador, G; de la Hoya, M; Barroso, A; Felipe-Ponce, V; Serrano-Blanch, R; Hinojo, C; Miramar-Gallart, M D; Urioste, M; Caldés, T; Santillan-Garzón, S; Benitez, J; Osorio, A

2017-02-01

There is still a considerable percentage of hereditary breast and ovarian cancer (HBOC) cases not explained by BRCA1 and BRCA2 genes. In this report, next-generation sequencing (NGS) techniques were applied to identify novel variants and/or genes involved in HBOC susceptibility. Using whole exome sequencing, we identified a novel germline mutation in the moderate-risk gene ATM (c.5441delT; p.Leu1814Trpfs*14) in a family negative for mutations in BRCA1/2 (BRCAX). A case-control association study was performed to establish its prevalence in Spanish population, in a series of 1477 BRCAX families and 589 controls further screened, and NGS panels were used for ATM mutational screening in a cohort of 392 HBOC Spanish BRCAX families and 350 patients affected with diseases not related to breast cancer. Although the interrogated mutation was not prevalent in case-control association study, a comprehensive mutational analysis of the ATM gene revealed 1.78% prevalence of mutations in the ATM gene in HBOC and 1.94% in breast cancer-only BRCAX families in Spanish population, where data about ATM mutations were very limited. ATM mutation prevalence in Spanish population highlights the importance of considering ATM pathogenic variants linked to breast cancer susceptibility.

Differential exudation of two benzoxazinoids--one of the determining factors for seedling allelopathy of Triticeae species.

Science.gov (United States)

Belz, Regina G; Hurle, Karl

2005-01-26

Benzoxazinoids (Bx) are natural phytotoxins that function as chemical defense compounds in several species. The release of Bx by intact plant roots associated these compounds with root allelopathy in Triticeae species; however, the significance of exudate concentrations of Bx for plant-plant interactions is still a controversial question. A biological screening of 146 cultivars of four Triticeae species (Triticum aestivum L., Triticum durum Desf., Triticum spelta L., and Secale cereale L.) demonstrated a high cultivar dependence to suppress the root growth of Sinapis alba L. by root allelopathy in a dose-response bioassay. Only a few cultivars possessed a marked high or low allelopathic activity, whereby high-performance liquid chromatography-diode array detection analysis of root exudates revealed that these cultivars differed considerably in their ability to exude the two Bx aglucones, DIBOA [2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one] and DIMBOA [2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one]. The total amount of DIBOA and DIMBOA exuded showed a significant correlation to the growth inhibition in bioassay with a statistically estimated contribution to the overall allelopathic effect of 48-72%. In a bioassay with pure phytotoxins, Bx concentrations consistent with the amounts quantified in the screening bioassay caused detrimental effects on S. alba and almost reproduced the statistically estimated contribution. The observed causal association between the allelopathic activity under laboratory conditions and the exudate concentrations of Bx suggests that this association might have implications for the interference of Triticeae species in natural plant communities.

"Causality and Subjectivity in Spanish Connectives : Exploring the use of automatic subjectivity analyses in various text types"

NARCIS (Netherlands)

Santana Covarrubias, A.C.; Nieuwenhuijsen, D.; Spooren, W.P.M.S. (Wilbert); Sanders, T.J.M.

2017-01-01

Causality and subjectivity are relevant cognitive principles in the categorization of coherence relations and connectives. Studies in various languages have shown how both notions can explain the meaning and use of different connectives. However, the Spanish language has been understudied from this

Informe sobre el proyecto contrastivo hispano-hungaro (Report on the Spanish-Hungarian Contrastive Project)

Science.gov (United States)

Fulei-Szanto, Andres

1974-01-01

A description of a contrastive linguistics project in Hungary aiming to augment linguistic theories in the Spanish language and propound theories for scientific and artistic translation. (Text is in Spanish.) (CK)

Semantic and Pragmatic Functions of the Spanish Diminutive in Spanish in Contact with Quechua.

Science.gov (United States)

Escobar, Anna Maria

2001-01-01

Presents data from the Spanish of Quechua-Spanish bilinguals that exemplify a contact situation that gives rise to a process called structural interference. Concentrates on the use of the diminutive in the Spanish of speakers of Spanish in the Andes. (Author/VWL)

Perched-Water Evaluation for the Deep Vadose Zone Beneath the B, BX, and BY Tank Farms Area of the Hanford Site

Energy Technology Data Exchange (ETDEWEB)

Truex, Michael J.; Oostrom, Martinus; Carroll, KC; Chronister, Glen B.

2013-06-28

Perched-water conditions have been observed in the vadose zone above a fine-grained zone that is located a few meters above the water table within the B, BX, and BY Tank Farms area. The perched water contains elevated concentrations of uranium and technetium-99. This perched-water zone is important to consider in evaluating the future flux of contaminated water into the groundwater. The study described in this report was conducted to examine the perched-water conditions and quantitatively evaluate 1) factors that control perching behavior, 2) contaminant flux toward groundwater, and 3) associated groundwater impact.

Spanish nuclear industry

International Nuclear Information System (INIS)

1994-01-01

In this book published to commemorate the twentieth anniversary of the Spanish Nuclear Society, it is included a report on the Spanish Nuclear Industry. The Spanish Companies and Organizations in nuclear world are: CIEMAT, Empresarios Agrupados, ENRESA, ENUSA, ENDESA, Grupo Iberdrola, LAINSA, INITEC AND TECNATOM. Activities, history and research programs of each of them are included

Randomized comparison of deliverability and in-hospital complications in implantation of BxSonic(R), Express(R), and Flexmaster(R) coronary stents

DEFF Research Database (Denmark)

Thuesen, Leif; Galløe, Anders; Thayssen, Per

2005-01-01

in a native coronary artery were included in the study. There were 494 (664) patients (treated lesions) in the BxSonic(R), 499 (657) in the Express(R) and 500 (658) in the Flexmaster(R) groups. The groups were well matched with regard to age, sex, diabetes, smoking, hypercholesterolemia, hypertension...

21 CFR 290.6 - Spanish-language version of required warning.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Spanish-language version of required warning. 290... (CONTINUED) DRUGS: GENERAL CONTROLLED DRUGS General Provisions § 290.6 Spanish-language version of required... of this drug to any person other than the patient for whom it was prescribed.” The Spanish version of...

(E-2-((4R,5R-5-((Benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol

Directory of Open Access Journals (Sweden)

Carlos R. Carreras

2010-04-01

Full Text Available The synthesis of (E-2-((4R,5R-5-((benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol by a one-step reduction of the appropriate 2-substituted butenolide is reported. Product characterization was carried out by IR, 1H NMR, 13C NMR, MS, elemental analysis and optical rotation.

Fostering Entrepreneurship at the University: A Spanish Empirical Study

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José Luis VÁZQUEZ

2011-02-01

Full Text Available This study aims to suggest best practices for improving the effectiveness of entrepreneurship education programs in the European area, based on their impact on expected attitudes of undergraduate students towards business startup as a career choice. Particularly, the paper presents some results from a study carried out in two Spanish universities aimed at validating a structure of entrepreneurship education based on a double component of curricular teaching and extracurricular support, and to analyze their effect upon undergraduates’ entrepreneurial selfefficacy and outcome expectations as immediate antecedents of entrepreneurial intentions and behaviors. Sample was comprised of 800 university students, and statistical treatment of data was based on factorial and regression analyses. Findings underline the very limited involvement of Spanish universities in entrepreneurship education as perceived by students, together with the existence of different effects of curricular and extracurricular elements when fostering entrepreneurial careers among future graduates. Implications of these results and limitations of the study are discussed.

A risk score to predict type 2 diabetes mellitus in an elderly Spanish Mediterranean population at high cardiovascular risk.

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Marta Guasch-Ferré

Full Text Available INTRODUCTION: To develop and test a diabetes risk score to predict incident diabetes in an elderly Spanish Mediterranean population at high cardiovascular risk. MATERIALS AND METHODS: A diabetes risk score was derived from a subset of 1381 nondiabetic individuals from three centres of the PREDIMED study (derivation sample. Multivariate Cox regression model ß-coefficients were used to weigh each risk factor. PREDIMED-personal Score included body-mass-index, smoking status, family history of type 2 diabetes, alcohol consumption and hypertension as categorical variables; PREDIMED-clinical Score included also high blood glucose. We tested the predictive capability of these scores in the DE-PLAN-CAT cohort (validation sample. The discrimination of Finnish Diabetes Risk Score (FINDRISC, German Diabetes Risk Score (GDRS and our scores was assessed with the area under curve (AUC. RESULTS: The PREDIMED-clinical Score varied from 0 to 14 points. In the subset of the PREDIMED study, 155 individuals developed diabetes during the 4.75-years follow-up. The PREDIMED-clinical score at a cutoff of ≥6 had sensitivity of 72.2%, and specificity of 72.5%, whereas AUC was 0.78. The AUC of the PREDIMED-clinical Score was 0.66 in the validation sample (sensitivity = 85.4%; specificity = 26.6%, and was significantly higher than the FINDRISC and the GDRS in both the derivation and validation samples. DISCUSSION: We identified classical risk factors for diabetes and developed the PREDIMED-clinical Score to determine those individuals at high risk of developing diabetes in elderly individuals at high cardiovascular risk. The predictive capability of the PREDIMED-clinical Score was significantly higher than the FINDRISC and GDRS, and also used fewer items in the questionnaire.

The Spanish participation in the SKA

Science.gov (United States)

Verdes-Montenegro, L.; Garrido, J.; González-García, M.

2017-03-01

The Square Kilometre Array (SKA) will be a radio interferometer aiming to answer fundamental questions in Astrophysics, Fundamental Physics, and Astrobiology. It will be composed of thousands of antennas distributed over distances of more than 3000 kilometres on both Africa and Australia. The SKA has been recently identified as a Landmark Project in the European Strategy Forum on Research Infrastructures (ESFRI) roadmap. Spain has been participating in SKA-related activities since the 1990s, coordinated since 2011 by the Instituto de Astrofísica de Andalucía (IAA-CSIC). Up to now, 21 researchers participate in 7 out of the 11 main SKA Science Working Groups, and a total of 119 researchers from 40 Spanish centres have participated in the Spanish SKA White Book, published in 2015. From a technological point of view, more than 20 research centres and companies are contributing to the design of the SKA as part of 7 international consortia. The Spanish contribution was estimated in 2M euro (2014), officially recognized by the SKA Organisation Director General in a letter to the Spanish Ministry of Economy and Competitiveness. In addition, the Spanish Astronomy Infrastructures Network (RIA from its Spanish initials) issued a recommendation on the interest of the scientific community and industry that Spain explores the possibility to join the SKA project as Full Member before the construction phase starts. In December 2015, the Spanish Secretary of State of Research, Development and Innovation sent a letter to the SKA Organisation Director General proposing to establish a dialogue in order to explore scenarios for Spain to join the SKA, what constitutes a further motivation for the Spanish community to continue its efforts.

Romanian and Spanish Cultural Crossings

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Anisoara Popa

2010-06-01

Full Text Available Much more appreciated and known in his time than by posterity, V.A.Urechia was ahistorian, politician and learned man, formed together with great personalities of the generation of the40's, A.I.Cuza's collaborator (the first ruler of the United Principalities, and also our first hispanist.After finishing his studies in Paris, he married Francoise Josephine Dominique Plano, the daughter ofQueen Isabela's of Spain personal doctor, Urechia showed a constant interest and maintained strongconnections with the Spanish cultural space that he discovered to be the origin of the foundingemperor of Dacia Traiana. The subject-matter of the present paper is Urechia's "capital of Spanisheducation" (enhanced in time, the contacts with the great personalities of the Spanish culture of histime , that can be reconstituted due to his work, his memoires, his letters a intercultural dialogue andarticles published in the Spanish and Romanian press, as well as the influence of those contacts on thepersonality, method, and purpose of his cultural approaches. Moreover, we are to point out thecontribution that the personalities had in the intercultural dialogue in Europe, at the end of the 19thcentury.

Experience with a Spanish-language laparoscopy website.

Science.gov (United States)

Moreno-Sanz, Carlos; Seoane-González, Jose B

2006-02-01

Although there are no clearly defined electronic tools for continuing medical education (CME), new information technologies offer a basic platform for presenting training content on the internet. Due to the shortage of websites about minimally invasive surgery in the Spanish language, we set up a topical website in Spanish. This study considers the experience with the website between April 2001 and January 2005. To study the activity of the website, the registry information was analyzed descriptively using the log files of the server. To study the characteristics of the users, we searched the database of registered users. We found a total of 107,941 visits to our website and a total of 624,895 page downloads. Most visits to the site were made from Spanish-speaking countries. The most frequent professional profile of the registered users was that of general surgeon. The development, implementation, and evaluation of Spanish-language CME initiatives over the internet is promising but presents challenges.

Validation of a Spanish version of the Revised Fibromyalgia Impact Questionnaire (FIQR)

Science.gov (United States)

2013-01-01

Background The Revised version of the Fibromyalgia Impact Questionnaire (FIQR) was published in 2009. The aim of this study was to prepare a Spanish version, and to assess its psychometric properties in a sample of patients with fibromyalgia. Methods The FIQR was translated into Spanish and administered, along with the FIQ, the Hospital Anxiety Depression Scale (HADS), the 36-Item Short-Form Health Survey (SF-36), and the Brief Pain Inventory (BPI), to 113 Spanish fibromyalgia patients. The administration of the Spanish FIQR was repeated a week later. Results The Spanish FIQR had high internal consistency (Cronbach’s α was 0.91 and 0.95 at visits 1 and 2 respectively). The test-retest reliability was good for the FIQR total score and its function and symptoms domains (intraclass correlation coefficient (ICC > 0.70), but modest for the overall impact domain (ICC = 0.51). Statistically significant correlations (p FIQ scores, as well as between the FIQR scores and the remaining scales’ scores. Conclusions The Spanish version of the FIQR has a good internal consistency and our findings support its validity for assessing fibromyalgia patients. It might be a valid instrument to apply in clinical and investigational grounds. PMID:23915386

Higher education needs for the ICT Spanish market Higher education needs for the ICT Spanish market Higher education needs for the ICT Spanish market

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Antoni Ras

2011-11-01

Full Text Available Purpose: The main objective of the paper is to clarify the expectations held in the realm of business and by employers, in relation to the main educational parameters that respond to the employment needs of the Information and Communication Technology (ICT market in Spain, considering both technical and managerial knowledge. It also assesses whether the Spanish Technical University is providing its graduates with the knowledge currently demanded by the sector.Design/methodology/approach: The report is based on a survey completed by 43 companies, which constitutes more than 60% of the sector and is representative of the entire range of subsectors that constitute the vast ICT industry in Spain. According to the sample construction, post-stratification has been used for analyzing global results. Responses have been weighted according to the proportion that represents the employees’ population of the Spanish ICT sector.Findings: As a first conclusion of the current research it should be noted that in terms of technological knowledge, the gap between what the industry requires and the skills graduates can offer is, in general, much smaller than the gap relating to business management skills, where differences exceeding 25% have been demonstrated. This would suggest that the Spanish ICT sector needs to improve learning in the subjects related to business management.Originality/value: Finally, as an innovate factor since there are no previous bibliographic references on this topic, a surprising conclusion is that a significant segment of the Spanish ICT sector, specifically 51,2 % of the companies surveyed, did not distinguish between professional profiles, expressed indifference, and were equally likely to employ graduates as postgraduates. Although when the market was asked about the preferred profile for managerial positions, the results are quite different: 83.7% of respondents preferred a superior engineer qualification; 16.3%Purpose: The

[Nursing in the movies: its image during the Spanish Civil War].

Science.gov (United States)

Siles González, J; García Hernández, E; Cibanal Juan, L; Gallardo Frías, Y; Lillo Crespo, M

1998-12-01

The cinema had carried out a determining role in the development of stereotypes and in a wide gamut of models related to real life situations. The objective of this analysis is to determine the influence cinema had on the image of nurses during the Spanish Civil War from 1936-1939. These are the initial hypotheses: the role of Spanish nurses during the civil war was reflected by both sides in their respective movie productions; and the image of nurses shown in these films, on both sides, presents a conflicting role concept for women in society. Following strategies developed by specialists in film analysis (Bondwell 1995, Uneso 1995, Carmona 1991) a total of 453 movie productions, 360 on the republican side and 93 on the national side, were reviewed. These films were listed in the Spanish National Films Library records. After analyzing the Spanish cinema productions during the Spanish Civil War, data relating to 453 films were identified. The genre included documents, news programs and fiction movies. 77 were produced in 1936, 235 in 1937, 102 in 1938 and 39 in 1939. A tremendous difference exists between the republican productions, 79% of the total, and the national productions. By genres, the types produced on the republican side were: in 1936, 53 documentals, 4 news programs and 9 fiction films; in 1937, 186 documentals, 5 news programs and 19 fiction films; in 1938, 72 documentals, 1 news programs and 2 fiction films; in 1939, 2 documentals and 2 fiction films. On the national side, their productions were: in 1936, 10 documentals and 1 fiction film; in 1937, 22 documentals, 2 news programs and 1 fiction film; in 1938, 19 documentals and 3 news programs; in 1939, 29 documentals and 6 fiction films. During the Spanish Civil War, movies produced by both sides made an effort to reflect their ideal woman as a stereotypical ideal nurse. This ideal nurse showed the values, ideas, aesthetics and prejudices each side held in the war.

English-Speaking and Spanish-Speaking Domestic Violence Perpetrators: An MMPI-2 Assessment

Science.gov (United States)

Scott, Ronald L.; Flowers, John V.; Bulnes, Alejandro; Olmsted, Eileen; Carbajal-Madrid, Pedro

2009-01-01

The use of assessments to characterize domestic violence perpetrators continues to develop with an emphasis on increasing the effectiveness of domestic violence interventions. The present study examines and compares Minnesota Multiphasic Personality Inventory (MMPI)-2 responses from 41 English-speaking and 48 Spanish-speaking men who were in…

Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer

International Nuclear Information System (INIS)

Ramani, Vishnu C; Hennings, Leah; Haun, Randy S

2008-01-01

In a previous report we have demonstrated that the chymotryptic-like serine protease kallikrein 7 (KLK7/hK7) is overexpressed in pancreatic cancer. In normal skin, hK7 is thought to participate in skin desquamation by contributing in the degradation of desmosomal components, such as desmogleins. Thus, the ability of hK7 to degrade desmogleins was assessed and the effect of hK7 expression on desmoglein 2 was examined in cultured pancreatic cancer cells. The expression of Dsg1, Dsg2, and Dsg3 in pancreatic tissues was examined by immunohistochemistry and their expression in two pancreatic cancer cell lines, BxPC-3 and Panc-1, was determined by western blot analysis. The ability of hK7 to degrade Dsg1 and Dsg2 was investigated using in vitro degradation assays. BxPC-3 cells stably transfected to overexpress hK7 were used to examine the effect of hK7 on cell-surface resident Dsg2. The levels of immunoreactive Dsg1 and Dsg2 were reduced in pancreatic adenocarcinomas compared with both normal pancreatic and chronic pancreatitis tissues. Among the desmosomal proteins examined, Dsg2 exhibited robust expression on the surface of BxPC-3 cells. When hK7 was overexpressed in this cell line, there was a significant increase in the amount of soluble Dsg2 released into the culture medium compared with vector-transfected control cells. A reduction in the amount of the cell adhesion components Dsg1 and Dsg2 in pancreatic tumors suggests that loss of these desmosomal proteins may play a role in pancreatic cancer invasion. Using in vitro degradation assays, both Dsg1 and Dsg2 could be readily proteolyzed by hK7, which is overexpressed in pancreatic adenocarcinomas. The enforced expression of hK7 in BxPC-3 cells that express significant amounts of Dsg2 resulted in a marked increase in the shedding of soluble Dsg2, which is consistent with the notion that aberrant expression of hK7 in pancreatic tumors may result in diminished cell-cell adhesion and facilitate tumor cell invasion

Marginalia. The Literary Independence of Spanish America

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Juan Guillermo Gómez García

2010-12-01

Full Text Available This article discusses some of the characteristic problems and issues of the so-called “literary independence” of Spanish America in the light of its political emancipation from Spain. This topic goes beyond the temporal framework or the periodization of the wars of independence; instead, it covers the entire nineteenth century and part of the twentieth, and appears discontinuously and non-simultaneously in the different nations. The path followed by Spanish American literature was filled with vicissitudes,manifestations, and regressions of diverse types. The paper specifically analyzes La biblioteca americana and El repertorio americano by the Venezuelan, Andrés Bello, and Juan García del Río, a native of Cartagena, as well as the role of the young Argentinean Domingo F. Sarmiento, author of Facundo, in the genesis and first outlines of an independent Spanish American “literary expression”.

An Online Spanish Learners’ Dictionary: The DAELE Project

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Blanca Arias-Badia

2014-12-01

Full Text Available Current online dictionaries for learners of Spanish as a second language largely just reproduce their printed counterparts. This report summarizes the advances made in the DAELE, a prototype dictionary for learners of Spanish as a second language that has been designed solely for online publication. The purpose and main features of the macro- and microstructure of the dictionary are briefly described, as well as the methodology whereby the data are collected and the first steps taken to include the most significant collocations by applying a method based on collocational networks.

Migration of Spanish nurses 2009-2014. Underemployment and surplus production of Spanish nurses and mobility among Spanish registered nurses: A case study.

Science.gov (United States)

Galbany-Estragués, Paola; Nelson, Sioban

2016-11-01

After the financial crisis of 2008, increasing numbers of nurses from Spain are going abroad to work. To examine the health and workforce policy trends in Spain between 2009 and 2014 and to analyze their correlation with the migration of nurses. Single embedded case study. We examined data published by: Health Statistics, Organization for Economic Cooperation and Development (1996 to 2013); Ministry of Education, Culture and Sports (2006 to 2013); Ministry of Employment and Social Security (2009 to 2014); Ministry of Health, Social Services and Equality (1997 to 2014); and National Institute of Statistics (1976 to 2014). In addition to reviewing the scholarly literature on the topic in Spanish and English, we also examined Spanish mobility laws and European directives. We used the Organization for Economic Cooperation and Development definition of "professionally active nurses" which defines practising nurses and other nurses as those for whom their education is a prerequisite for employment as a nurse. Moreover, we used the term "nursing graduate" as defined by Spanish Ministry of Education to describe those who have obtained a recognized qualification in nursing in a given year, the term "registered nurses" is defined by Spanish law as nurses registered in the Nurses Associations and "unemployed nurses" are those without work and registered as seeking employment. A transformation of the Spanish health system has reduced the number of employed nurses per capita since 2010. Moreover, reductions in public spending, labour market reforms and widespread unemployment have affected nurses in two ways: first by increasing the number of applicants per vacancy between 2009 and 2013, and second, by an increase in casual positions. However, despite the poor job market and decreasing job security, the number of registered nurses and nursing graduates in Spain per year has continued to grow, increasing the pressure on the labour market. Spain is transforming from a stable

7 CFR 51.2730 - U.S. No. 1 Spanish.

Science.gov (United States)

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Spanish. 51.2730 Section 51.2730... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2730 U.S. No. 1 Spanish. “U.S. No. 1 Spanish” consists of shelled Spanish type peanut kernels which are whole and free...

Adaptation and validation of the Spanish version of the ORTO-15 questionnaire for the diagnosis of orthorexia nervosa.

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María Laura Parra-Fernandez

Full Text Available The aim of this study was the validation and analysis of the psychometric properties of a Spanish translation of the ORTO-15 questionnaire; an instrument designed to assess orthorexia nervosa behavior. Four hundred and fifty-four Spanish university students (65% women aged between 18 and 51 years (M = 21.48 ± 0.31 completed the Spanish version of ORTO-15 and the Eating Disorders Inventory-2 (EDI-2. The Principal Component Analysis suggested a three-factor structure for the abbreviated 11-item version of the instrument. The internal consistency of the measurement was adequate (Cronbach's alpha = 0.80. The proposed test demonstrated a good predictive capacity at a threshold value of <25 (efficiency 84%, sensitivity 75% and specificity 84%. Our results support the psychometric properties of the proposed Spanish shortened-version of the ORTO-15 as being a reliable tool for assessing orthorexia nervosa. Its use is expected to greatly contribute to a better understanding of the impact of this disorder in Spain.

Cytotoxic Cytochalasins and Other Metabolites from Xylariaceae sp. FL0390, a Fungal Endophyte of Spanish Moss.

Science.gov (United States)

Xu, Ya-Ming; Bashyal, Bharat P; Liu, Mangping X; Espinosa-Artiles, Patricia; U'Ren, Jana M; Arnold, A Elizabeth; Gunatilaka, A A Leslie

2015-10-01

Two new metabolites, 6-oxo-12-norcytochalasin D (1) and 4,5-di-isobutyl-2(1H)-pyrimidinone (2), together with seven known metabolites, cytochalasins D (3), Q (4), and N (5), 12-hydroxyzygosporin G (6), heptelidic acid chlorohydrin (7), (+)-heptelidic acid (8), and trichoderonic acid A (9), were isolated from Xylariaceae sp. FL0390, a fungal endophyte inhabiting Spanish moss, Tillandsia usneoides. Metabolite 1 is the first example of a 12-norcytochalasin. All metabolites, except 2 and 9, showed cytotoxic activity in a panel of five human tumor cell lines with IC50S of 0.2-5.0 μM.

Gender sensitive language policies and deconstruction of gender stereotypes in textbooks of Spanish as a foreign language

Directory of Open Access Journals (Sweden)

Ana Kuzmanović Jovanović

2015-12-01

Full Text Available This paper examines the impact of gender representations in Spanish/L2 textbooks on perpetuation or deconstruction of gender stereotypes in the classroom. Although the results of numerous studies of gender representation in such books performed in the past two decades suggest that teaching materials have been an important instrument in perpetuating gender stereotypes, recent researches have revealed certain changes in this area. The present analysis supports these findings. The research corpus consists of eleven textbooks of Spanish/L2 (level A1 and A2 by different Spanish publishers, all of them published in the last four years. The gender roles in which women and men appear are critically analyzed. The results of the analysis suggest that there has been a conscious effort by both authors and editors in order to change the stereotypical gender representation in these didactic materials. We offer an explanation for these changes suggesting that they can be accounted for by the action of a different model of gender sensitive language policies, the bottom-up model, where the crucial factors of change are not the activities of the official institutions but rather are to be found in different communities of practice, i.e., all people involved in creating, publishing and distributing teaching materials, as well as linguists who investigate the relationship between language and gender.

Prevalence of 2314delG mutation in Spanish patients with Usher syndrome type II (USH2).

Science.gov (United States)

Beneyto, M M; Cuevas, J M; Millán, J M; Espinós, C; Mateu, E; González-Cabo, P; Baiget, M; Doménech, M; Bernal, S; Ayuso, C; García-Sandoval, B; Trujillo, M J; Borrego, S; Antiñolo, G; Carballo, M; Nájera, C

2000-06-01

The Usher syndrome (USH) is a group of autosomal recessive diseases characterized by congenital sensorineural hearing loss and retinitis pigmentosa. Three clinically distinct forms of Usher syndrome have so far been recognized and can be distinguished from one another by assessing auditory and vestibular function. Usher syndrome type II (USH2) patients have congenital moderate-to-severe nonprogressive hearing loss, retinitis pigmentosa, and normal vestibular function. Genetic linkage studies have revealed genetic heterogeneity among the three types of USH, with the majority of USH2 families showing linkage to the USH2A locus in 1q41. The USH2A gene (MIM 276901) has been identified: three mutations, 2314delG, 2913delG, and 4353-54delC, were initially reported in USH2A patients, the most frequent of which is the 2314delG mutation. It has been reported that this mutation can give rise to typical and atypical USH2 phenotypes. USH2 cases represent 62% of all USH cases in the Spanish population, and 95% of these cases have provided evidence of linkage to the USH2A locus. In the present study, the three reported mutations were analyzed in 59 Spanish families with a diagnosis of USH type II. The 2314delG was the only mutation identified in our population: it was detected in 25% of families and 16% of USH2 chromosomes analyzed. This study attempts to estimate the prevalence of this common mutation in a homogeneous Spanish population.

Mutations in myosin VIIA (MYO7A) and usherin (USH2A) in Spanish patients with Usher syndrome types I and II, respectively.

Science.gov (United States)

Nájera, Carmen; Beneyto, Magdalena; Blanca, José; Aller, Elena; Fontcuberta, Ana; Millán, José María; Ayuso, Carmen

2002-07-01

Usher syndrome is an autosomal recessive disorder characterized by congenital hearing impairment and retinitis pigmentosa. Three clinical types are known (USH1, USH2 and USH3), and there is an extensive genetic heterogeneity, with at least ten genes implicated. The most frequently mutated genes are MYO7A, which causes USH1B, and usherin, which causes USH2A. We carried out a mutation analysis of these two genes in the Spanish population. Analysis of the MYO7A gene in patients from 30 USH1 families and sporadic cases identified 32% of disease alleles, with mutation Q821X being the most frequent. Most of the remaining variants are private mutations. With regard to USH2, mutation 2299delG was detected in 25% of the Spanish patients. Altogether the mutations detected in USH2A families account for 23% of the disease alleles. Copyright 2002 Wiley-Liss, Inc.

Additional psychometric data for the Spanish Modified Dental Anxiety Scale, and psychometric data for a Spanish version of the Revised Dental Beliefs Survey.

Science.gov (United States)

Coolidge, Trilby; Hillstead, M Blake; Farjo, Nadia; Weinstein, Philip; Coldwell, Susan E

2010-05-13

Hispanics comprise the largest ethnic minority group in the United States. Previous work with the Spanish Modified Dental Anxiety Scale (MDAS) yielded good validity, but lower test-retest reliability. We report the performance of the Spanish MDAS in a new sample, as well as the performance of the Spanish Revised Dental Beliefs Survey (R-DBS). One hundred sixty two Spanish-speaking adults attending Spanish-language church services or an Hispanic cultural festival completed questionnaires containing the Spanish MDAS, Spanish R-DBS, and dental attendance questions, and underwent a brief oral examination. Church attendees completed the questionnaire a second time, for test-retest purposes. The Spanish MDAS and R-DBS were completed by 156 and 136 adults, respectively. The test-retest reliability of the Spanish MDAS was 0.83 (95% CI = 0.60-0.92). The internal reliability of the Spanish R-DBS was 0.96 (95% CI = 0.94-0.97), and the test-retest reliability was 0.86 (95% CI = 0.64-0.94). The two measures were significantly correlated (Spearman's rho = 0.38, p Spanish MDAS was higher. The significant relationships between dental attendance and questionnaire scores, as well as the difference in caries severity seen in those with high fear, add to the evidence of this scale's construct validity in Hispanic samples. Our results also provide evidence for the internal and test-retest reliabilities, as well as the construct validity, of the Spanish R-DBS.

A Responsive, Integrative Spanish Curriculum at UNC Charlotte

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Doyle, Michael S.

2010-01-01

The Spanish program at UNC Charlotte is timely and responsive because it is designed to meet documented societal (job market) needs in today's and tomorrow's global village and economy by providing graduates with strong specialties in English-Spanish translating and in business Spanish. It is integrative in that it does so while maintaining its…

The Effects of Input Enhancement and Text Length on Adult L2 Readers' Comprehension and Intake in Second Language Acquisition.

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Leow, Ronald P.

1997-01-01

Investigated the effects of written input enhancement and text length on college students' second-language comprehension and intake. First-year Spanish students were exposed to one of four conditions with enhanced and non-enhanced short and long text. Exposing students to short authentic reading materials facilitated reading comprehension but not…

Empirical validation of the CRAFFT Abuse Screening Test in a Spanish sample.

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Rial, Antonio; Kim-Harris, Sion; Knight, John R; Araujo, Manuel; Gómez, Patricia; Braña, Teresa; Varela, Jesús; Golpe, Sandra

2018-01-15

The CRAFFT Substance Abuse Screening Instrument, developed by the Center for Adolescents Substance Abuse Research (CeASAR) (Knight et al., 1999), is a screening tool for high-risk alcohol and drug risk consumption designed for use with adolescents. Since its publication it has been the subject of translations and validations in different countries, populations and contexts that have demonstrated its enormous potential. However, there is still no empirical validation study that would ensure its good psychometric performance in Spain. The aim of this paper is to develop an adapted version of the CRAFFT in Spanish and to analyze its psychometric properties in a sample of Spanish adolescents. For this purpose an individual interview was conducted on 312 adolescents aged between 12 and 18 years of age (M = 15.01; SD = 1.83) from the Galician community. The interview included a part of the Adolescent Diagnostic Interview (ADI) and the Problem Oriented Screening Instrument for Teenagers (POSIT). The results obtained, similar to those found in other countries, allow us to report that the Spanish version of the CRAFFT has a good psychometric behaviorproperties. It was found to have a satisfactory internal consistency with a Cronbach’s alpha value of .74. In terms of sensitivity and specificity, values of 74.4% and 96.4% respectively, were obtained and the area under the ROC curve was .946. The Spanish version of the CRAFFT is made available to researchers and professionals in the field of addictive behaviors, so that it can be used with the necessary psychometric guarantees.

Mutual Word Borrowings between the English and the Spanish Languages

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Aliya Rinatovna Ismagilova

2017-09-01

Full Text Available The contemporary world witnesses growing popularity of foreign languages learning and their role in the modern society. The article is devoted to the problem of mutual borrowings from English and Spanish languages. The aim of the article is to investigate new tendencies in the English words borrowings, their establishment in the Spanish language and the other way round. The Spanish language is one of the most widespread languages in the world and it is a native language for different nationalities. On the other hand, English has borrowed quite a lot of Spanish words as well. The mutual enrichment of the languages makes the process of language teaching specific and it is important in the modern process of globalization where languages are the main resource of international cooperation. The article contains both theoretical and practical materials dedicated to the investigation of this problem. This article may be useful for a wide range of readers, students, scientists, linguists in the study of modern Spanish and English languages.

Materiality Analysis for CSR Reporting in Spanish SMEs

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Elena Escrig-Olmedo

2012-01-01

Full Text Available Most corporate social responsibility (CSR standards have not been designedto be implemented in small and medium sized enterprises (SMEs. Giventhat 99% of Spanish companies are SMEs, this study aims to propose aselection of basic CSR material issues that, because of their usefulness andsignificance, should be adapted to Spanish SMEs and their stakeholders.This study provides a CSR model for SMEs that includes the most importantsocial, environmental, and corporate governance issues. This model, whichis based on expert knowledge, is useful for integrating sustainability in themanagement of SMEs and enhancing the management of stakeholders.

Effects of level and length of supplementation on leather characteristics of yearling Boer and Spanish wethers

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Thirty 7/8 Boer × 1/8 Spanish (B) and 29 Spanish (S) wethers were used in a trial with 110 (P1) and 108 d (P2) periods. Six B and 5 S were harvested at the beginning of the trial. The remaining animals were assigned to 4 groups, each having 6 B and 6 S, raised on pasture with unlimited access to ha...

Financial performance after the Spanish banking reforms: A comparative study of 19 commercial banks

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Pison F. Irene

2014-06-01

Full Text Available A diagnostic review of the Spanish financial system during the 2008 financial crisis reveals the emergency need for banking reform in the sector. In an attempt to evaluate the impact of the Spanish reform, the present study examines the bank´s performance before/after the reform was adopted, using data of 19 Spanish commercial banks extracted from the Global Vantage research database (Standard and Poor’s over the period 2006 to 2013. This study uses multivariable regression method to investigate the impact of the CAMELS rating system: capital adequacy, asset quality, management quality, liquidity and sensitivity to market risks on the bank´s performance such as earnings efficiency. The time-line of the study is essential because it helps us to determine the financial performance of Spanish commercial banks before the banking reforms during the financial crisis and an important set in terms of mergers and acquisition in the banking industry. The empirical results have found strong and positive evidence that Capital Adequacy, Management Capacity, Liquidity and Sensitivity to Market Risk are useful predictors of banks performance (earnings efficiency, thus, any reform pilot toward this banking indicators will eventually have a positive impact on banking performance. Base on the present study, the Spanish reform was so vital for better banking performance. Therefore, this study serves not only to academics but also to policy makers

Identifying randomized clinical trials in Spanish-language dermatology journals.

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Sanclemente, G; Pardo, H; Sánchez, S; Bonfill, X

2015-06-01

The necessary foundation for good clinical practice lies in knowledge derived from clinical research. Evidence from randomized clinical trials (RCTs) is the pillar on which decisions about therapy are based. To search exhaustively and rigorously to identify RCTs in dermatology journals published in Spanish. We located dermatology journals through the following search engines and indexes: PubMed, LILACS, SciELO, Periódica, Latindex, Índice Médico Español, C-17, IBECS, EMBASE, and IMBIOMED. We also sought information through dermatology associations and dermatologists in countries where Spanish was the usual language of publication, and we searched the Internet (Google). Afterwards we searched the journals electronically and manually to identify RCTs in all available volumes and issues, checking from the year publication started through 2012. Of 28 journals identified, we included 21 in the search. We found a total of 144 RCTs published since 1969; 78 (54%) were in Latin American journals and 66 (46%) were in Spanish journals. The most frequent disease contexts for RCTs in Spanish journals were psoriasis, mycoses, and acne vulgaris. In Latin American journals, the most frequent disease contexts were common warts, mycoses, acne vulgaris, and skin ulcers on the lower limbs. Manual searches identified more RCTs than electronic searches. Manual searches found a larger number of RCTs. Relatively fewer RCTs are published in Spanish and Latin American journals than in English-language journals. Internet facilitated access to full texts published by many journals; however, free open access to these texts is still unavailable and a large number of journal issues are still not posted online. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.

Bibliometric analysis of the Spanish MR radiological production (2001-2007)

International Nuclear Information System (INIS)

Miguel-Dasit, Alberto; Marti-Bonmati, Luis; Sanfeliu, Pilar

2008-01-01

Objective: To evaluate the number and characteristics of papers on MR imaging written by radiologists in Spain and published in 2001-2007 Medline-indexed journals, including a comparison with the MR research output from German radiological departments. Materials and methods: Specific search profiles were devised to retrieve items from the Medline database. Relationship with the topic and major thematic areas of the articles, publication year, journal, language of publication, and mean impact factors were analyzed. Spanish and the German institutions with the highest MR productivity were identified. Also, the number of articles from Spain and Germany published in their respective official journals (Radiologia and ROFO) was recorded. Results: There were 332 Spanish articles published in 101 different journals. The higher number of papers was published in Spanish radiology and non-radiology journals (n = 105, 32%, mean IF: 0.191). The journal with the higher number of articles was Radiologia (n = 51, 15%). 'Neuroradiology' was the most frequent topic (n = 139, 42%). The Spanish productivity on MR imaging was yearly stable (p = 0.67), with the higher percentage of papers (17%) published in 2006. The topic with the higher IF was 'neuroradiology' (IF: 2.317). There were no yearly variations for the three major thematic areas ('Neuro imaging': p = 0.64; 'Body imaging': p = 0.91; and 'Non-clinical miscellanea': p = 0.46). The highest number of MR publications was found in two Spanish institutions (Dr. Peset University Hospital and Vall d'Hebron Hospital) (both, n = 28, 8%). In comparison, there were 1681 articles on MR imaging from Germany, having the two most productive institutions more than 150 papers in this period (University Hospital Essen and Eberhard-Karls University of Tuebingen). The adjusted number of articles per million populations was 20.4 for Germany and 8.1 for Spain. A total of 395 (23%) articles originating from Germany were published in the official

Trajectories and Expectations in China. A Decentered Approach to Spanish International Mobility

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Amelia Sáiz López

2017-12-01

Full Text Available The decade of 2010 has awakened the research interest in emerging flows of qualified young people towards Europe and Latin America. Spanish international migration is not exhausted in these destinations. A decentralized approach allows studying the Spanish residents in Shanghai, elaborating a typology from the perspective of mobilities where processes analyzed separately in previous migration studies converge. The complexity of mobility is not only explained by the geographical or labor dimensions. Based on in-depth interviews, the proposed qualitative analysis shows the need to cross-link all dimensions involved in individual and collective decision-making and the different strategies, within a given gender system, and according to objectives, social and family positions, resources and capital, in the context of globalization.

On the worldsheet theory of the type IIA {text{Ad}}{{text{S}}_4} × mathbb{C}{mathbb{P}_3} superstring

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Sundin, Per

2010-04-01

We perform a detailed study of the type IIA superstring in {text{Ad}}{{text{S}}_4} × mathbb{C}{mathbb{P}_3} . After introducing suitable bosonic light-cone and fermionic kappa worldsheet gauges we derive the pure boson and fermion SU(2|2)×U(1) covariant light-cone Hamiltonian up to quartic order in fields. As a first application of our derivation we calculate energy shifts for string configurations in a closed fermionic subsector and successfully match these with a set of light-cone Bethe equations. We then turn to investigate the mismatch between the degrees of freedom of scattering states and oscillatory string modes. Since only light string modes appear as fundamental Bethe roots in the scattering theory, the physical role of the remaining 4 F + 4 B massive oscillators is rather unclear. By continuing a line of research initiated by Zarembo, we shed light on this question by calculating quantum corrections for the propagators of the bosonic massive fields. We show that, once loop corrections are incorporated, the massive coordinates dissolve in a continuum state of two light particles.

Spanish Occupation of Roussillon in 1815

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Matías Ramisa Verdaguer

2015-12-01

Full Text Available The subject of this article is the invasion of the French Pyrénées- Orientales department by Spanish troops under the orders of General Castaños in late August 1815, shortly after the Waterloo defeat and the occupation of France by the Seventh Coalition allies. The article also presents the situation before the Waterloo battle in the province of Catalonia, the preparation of the previously mentioned invasion and its consequences, all framed in the foreign policy of the Ferdinand VII government. The sources used in this work are the case files of the National Historical Archive (Madrid that relate to this episode, and specialized literature. The objective of this study was to relate a lesser-known event, occurred shortly after the end of the War of Independence, to highlight the scarce and indecisive Spanish foreign policy during the Congress of Vienna period. The Napoleonic invasion accentuated the Spanish internal crisis and the international decline of the country. This is reflected in the occupation of the Roussillon and rapid withdrawal ordered by General Castaños.

Temas y problemas del idioma espanol en la prensa (Spanish Language Topics and Problems in the Press).

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El Brocense; And Others

1980-01-01

This section consists of reprints on the following topics: (1) the misuse of "en"; (2) anglicisms; (3) widespread use of vulgar language; (4) an interview with Emilio Criado on Spanish language variation; (5) use of the feminine in professional titles; and (6) Spanish, the national language of Latin American countries. (AMH)

Spanish as a Second Language when L1 Is Quechua: Endangered Languages and the SLA Researcher

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Kalt, Susan E.

2012-01-01

Spanish is one of the most widely spoken languages in the world. Quechua is the largest indigenous language family to constitute the first language (L1) of second language (L2) Spanish speakers. Despite sheer number of speakers and typologically interesting contrasts, Quechua-Spanish second language acquisition is a nearly untapped research area,…

THE PHONOLOGICAL SYSTEM OF SPANISH

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Claudia S. Salcedo

2010-10-01

Full Text Available Spanish articulatory phonetics, the classification of sounds and the physiological mechanism used in the production of phonemes are discussed in this article. The process of learning a language consists of classifying sounds within the target language. Since the learner may be hearing the utterance in a different way than the native speaker some objective criteria are needed to classify sounds. If these distinctions are not mastered, he may be perceived as sounding awkward. Other phonological processes are applied in informal situations due to socio-linguistic factors such as age, social class, and education. Sound deletion in particular phonological environments are not done randomly by the speaker, but by necessity to retain semantic comprehension. Allophonic choices within phonemes make up the dialect for a particular area.