WorldWideScience

Sample records for www.scielo.org.ar

  1. Propuesta de un buscador para artículos indizados a SciELO

    Directory of Open Access Journals (Sweden)

    C Hugo Arroyo-Hernández

    2010-08-01

    Full Text Available La biblioteca electrónica SciELO “Scientific Electronic Library Online” (www.scielo.org permite el acceso gratuito a textos completos de revistas científicas y opera como una red de bibliotecas constituida por diferentes sitios web, en la cual participan 14 países (Argentina, Brasil, Bolivia, Chile, Costa Rica, Colombia, Cuba, España, México, Paraguay, Perú, Portugal, Sudáfrica y Venezuela (...

  2. http://www.vbgsn.org

    International Development Research Centre (IDRC) Digital Library (Canada)

    http://www.vbgsn.org. LES TIC POUR PREVENIR ET. LUTTER CONTRE LES VBG. GROUPE D'ETUDES ET DE RECHERCHES GENRE ET SOCIETES. Une base technique utilisant des solutions open source. Il s'agit d'une plateforme web et mobile qui permet aux parties prenantes de pouvoir remonter et partager les ...

  3. www.elearnSCI.org

    DEFF Research Database (Denmark)

    Chhabra, H S; Harvey, Lee; Muldoon, S

    2013-01-01

    OBJECTIVE: To develop a web-based educational resource for health professionals responsible for the management of spinal cord injury (SCI). The resource:www.elearnSCI.org is comprised of seven learning modules, each subdivided into various submodules. Six of the seven modules address the educatio......OBJECTIVE: To develop a web-based educational resource for health professionals responsible for the management of spinal cord injury (SCI). The resource:www.elearnSCI.org is comprised of seven learning modules, each subdivided into various submodules. Six of the seven modules address...... the educational needs of all disciplines involved in comprehensive SCI management. The seventh module addresses prevention of SCI. Each submodule includes an overview, activities, self-assessment questions and references. DEVELOPMENT OF THE RESOURCE: Three hundred and thirty-two experts from The International...... Spinal Cord Society (ISCoS) and various affiliated societies from 36 countries were involved in developing the resource through 28 subcommittees. The content of each submodule was reviewed and approved by the Education and Scientific Committees of ISCoS and finally by an Editorial Committee of 23 experts...

  4. Regional information portal - www.peipsi.org / Piret Uus

    Index Scriptorium Estoniae

    Uus, Piret

    2004-01-01

    Piirkondlik infoportaal - www.peipsi.org - pakub mitmekülgset teavet Peipsi Koostöö Keskuse tegevuse, projektide, teadusuuringute tulemuste, aruannete kohta, samuti on kättesaadav info Peipsi järve keskkonnaseisundist, ajaloost, kultuurist, geograafiast jne

  5. Effect of and satisfaction with www.elearnSCI.org for training of nurse students

    DEFF Research Database (Denmark)

    Liu, N; Li, X W; Zhou, M W

    2014-01-01

    STUDY DESIGN: Interventional training session. OBJECTIVE: To investigate the effect and satisfaction with didactic training using printed text of a submodule of www.elearnSCI.org for nurse students and to assess the answers of each question. SETTING: A Peking University teaching hospital. METHODS......: Twenty-eight nurse students in two groups (14 in each) were involved. Only group A received a translated print-out of the slides from the 'Nursing management' submodule in www.elearnSCI.org for 1-h self-study before the class. At the beginning of class, both groups were tested using the self assessment...... presentation are effective methods for training the content of www.elearnSCI.org to nurse students. The training satisfaction of this submodule within the www.elearnSCI.org is favorable....

  6. RSS (http://www.iaees.org/publications/journals/arthropods/rss.xml

    Directory of Open Access Journals (Sweden)

    Arthropods (ISSN 2224-4255

    Full Text Available Arthropods ISSN 2224-4255 URL: http://www.iaees.org/publications/journals/arthropods/online-version.asp RSS: http://www.iaees.org/publications/journals/arthropods/rss.xml E-mail: arthropods@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope ARTHROPODS (ISSN 2224-4255 is an international journal devoted to the publication of articles on various aspects of arthropods, e.g., ecology, biogeography, systematics, biodiversity (species diversity, genetic diversity, et al., conservation, control, etc. The journal provides a forum for examining the importance of arthropods in biosphere (both terrestrial and marine ecosystems and human life in such fields as agriculture, forestry, fishery, environmental management and human health. The scope of Arthropods is wide and embraces all arthropods-insects, arachnids, crustaceans, centipedes, millipedes, and other arthropods. Articles/short communications on new taxa (species, genus, families, orders, etc. and new records of arthropods are particularly welcome. Authors can submit their works to the email box of this journal, arthropods@iaees.org. All manuscripts submitted to this journal must be previously unpublished and may not be considered for publication elsewhere at any time during review period of this journal. Authors are asked to read Author Guidelines before submitting manuscripts. In addition to free submissions from authors around the world, special issues are also accepted. The organizer of a special issue can collect submissions (yielded from a research project, a research group, etc. on a specific research topic, or submissions of a scientific conference for publication of special issue.

  7. Arthropods (http://www.iaees.org/publications/journals/arthropods/online-version.asp

    Directory of Open Access Journals (Sweden)

    arthropods@iaees.org

    Full Text Available Arthropods ISSN 2224-4255 URL: http://www.iaees.org/publications/journals/arthropods/online-version.asp RSS: http://www.iaees.org/publications/journals/arthropods/rss.xml E-mail: arthropods@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope ARTHROPODS (ISSN 2224-4255 is an international journal devoted to the publication of articles on various aspects of arthropods, e.g., ecology, biogeography, systematics, biodiversity (species diversity, genetic diversity, et al., conservation, control, etc. The journal provides a forum for examining the importance of arthropods in biosphere (both terrestrial and marine ecosystems and human life in such fields as agriculture, forestry, fishery, environmental management and human health. The scope of Arthropods is wide and embraces all arthropods-insects, arachnids, crustaceans, centipedes, millipedes, and other arthropods. Articles/short communications on new taxa (species, genus, families, orders, etc. and new records of arthropods are particularly welcome. Authors can submit their works to the email box of this journal, arthropods@iaees.org. All manuscripts submitted to this journal must be previously unpublished and may not be considered for publication elsewhere at any time during review period of this journal. Authors are asked to read Author Guidelines before submitting manuscripts. In addition to free submissions from authors around the world, special issues are also accepted. The organizer of a special issue can collect submissions (yielded from a research project, a research group, etc. on a specific research topic, or submissions of a scientific conference for publication of special issue.

  8. All rights reserved and www.bioline.org.br/ja Estimation of exit ...

    African Journals Online (AJOL)

    ADOWIE PERE

    and www.bioline.org.br/ja. Estimation of exit temperatures in the isentropic compression of real gases. 1 ..... other thermodynamic properties can be calculated within the framework of ... of negative compressibility) has no physical significance.

  9. RSS (http://www.iaees.org/publications/journals/environsc/rss.xml

    Directory of Open Access Journals (Sweden)

    Environmental Skeptics and Critics (ISSN 2224-4263

    Full Text Available Environmental Skeptics and Critics ISSN 2224-4263 URL: http://www.iaees.org/publications/journals/environsc/online-version.asp RSS: http://www.iaees.org/publications/journals/environsc/rss.xml E-mail: environsc@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope The more truth is debated, the clearer it becomes. Science will not proceed without debate and controversy. Wide and in-depth debate and controversy on human's knowledge, attitudes, policies and practices on the environment determines the future of our planet. There are numerous controversial and potentially controversial issues on environmental sciences and practices. ENVIRONMENTAL SKEPTICS and CRITICS (ISSN 2224-4263 is an international journal devoted to the publication of skeptical and critical articles/short communications/letters on theories, viewpoints, methodologies, practices, policies, etc., in ecological and environmental areas. The journal provides a forum for questioning, disputing, arguing, challenging, criticizing and judging known theories, methdologies, practices, and policies, etc., or presenting different ideas. The scope of Environmental Skeptics and Critics is wide and embraces all controversial, non-conclusive or unexplained issues in ecological and environmental areas. Authors can submit their works to the email box of this journal, environsc@iaees.org. All manuscripts submitted to this journal must be previously unpublished and may not be considered for publication elsewhere at any time during review period of this journal. Authors are asked to read Author Guidelines before submitting manuscripts. In addition to free submissions from authors around the world, special issues are also accepted. The organizer of a special issue can collect submissions (yielded from a research project, a research group, etc. on a specific research topic, or submissions of a scientific conference for publication of special issue.

  10. The influence of question design on the response to self-assessment in www.elearnSCI.org

    DEFF Research Database (Denmark)

    Liu, N; Li, X-W; Zhou, M-W

    2015-01-01

    STUDY DESIGN: This is an interventional training session. OBJECTIVE: The objective of this study was to investigate the difference in response to self-assessment questions in the original and an adjusted version for a submodule of www.elearnSCI.org for student nurses. SETTING: The study was condu......STUDY DESIGN: This is an interventional training session. OBJECTIVE: The objective of this study was to investigate the difference in response to self-assessment questions in the original and an adjusted version for a submodule of www.elearnSCI.org for student nurses. SETTING: The study...... was conducted in a teaching hospital affiliated to Peking University, China. METHODS: In all, 28 student nurses divided into two groups (groups A and B; 14 in each) received a print-out of a Chinese translation of the slides from the 'Maintaining skin integrity following spinal cord injury' submodule in www.elearnSCI...... be avoided because it would increase the number of correct answers arrived at by guessing. When using multiple-answer MCQs, it is recommended that the questions asked should be in accordance with the content within the www.elearnSCI.org....

  11. RSS (http://www.iaees.org/publications/journals/nb/rss.xml

    Directory of Open Access Journals (Sweden)

    Network Biology (ISSN 2220-8879

    Full Text Available Network Biology ISSN 2220-8879 URL: http://www.iaees.org/publications/journals/nb/online-version.asp RSS: http://www.iaees.org/publications/journals/nb/rss.xml E-mail: networkbiology@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope NETWORK BIOLOGY (ISSN 2220-8879; CODEN NBEICS is an open access, peer-reviewed international journal that considers scientific articles in all different areas of network biology. It is the transactions of the International Society of Network Biology. It dedicates to the latest advances in network biology. The goal of this journal is to keep a record of the state-of-the-art research and promote the research work in these fast moving areas. The topics to be covered by Network Biology include, but are not limited to: •Theories, algorithms and programs of network analysis •Innovations and applications of biological networks •Ecological networks, food webs and natural equilibrium •Co-evolution, co-extinction, biodiversity conservation •Metabolic networks, protein-protein interaction networks, biochemical reaction networks, gene networks, transcriptional regulatory networks, cell cycle networks, phylogenetic networks, network motifs •Physiological networks •Network regulation of metabolic processes, human diseases and ecological systems •Social networks, epidemiological networks •System complexity, self-organized systems, emergence of biological systems, agent-based modeling, individual-based modeling, neural network modeling, and other network-based modeling, etc. We are also interested in short communications that clearly address a specific issue or completely present a new ecological network, food web, or metabolic or gene network, etc. Authors can submit their works to the email box of this journal, networkbiology@iaees.org. All manuscripts submitted to this journal must be previously unpublished and may not be considered for publication elsewhere at any time during review period of this journal

  12. SciELO: un proyecto cooperativo para la difusión de la ciencia SciELO: A cooperative project for the dissemination of science

    Directory of Open Access Journals (Sweden)

    C. Bojo Canales

    2009-10-01

    Full Text Available Se describe el modelo SciELO (Scientific Electronic Library Online para la publicación y difusión electrónica de revistas científicas, su origen y evolución, su metodología, componentes, servicios y potencialidades, así como su implantación en España. Con 13 países participantes que suponen 8 portales certificados y 5 portales en desarrollo, más dos portales temáticos, en febrero de 2009 SciELO.org recogía 611 revistas y 195.789 artículos, de los cuales el 46% eran de Ciencias de la Salud, lo que lo convierte en una de las iniciativas de acceso abierto más importantes de cuantas existen. España se une al proyecto en 1999 y lanzó su portal "SciELO España" en 2001, con 4 revistas. En la actualidad incluye 39 títulos del área de Ciencias de la Salud, entre ellos la Revista Española de Sanidad Penitenciaria que se ha incorporado a la colección en 2007 y tiene accesibles 6 números correspondientes a los años 2007 y 2008. Se concluye afirmando que el modelo SciELO contribuye al desarrollo de la investigación y la ciencia, ofreciendo una solución eficiente y eficaz para impulsar y aumentar la difusión de las publicaciones científicas del área iberoamericana.The article describes the SciELO (Scientific Electronic Library Online model for the electronic publication and dissemination of scientific journals, its origin and evolution, methodology, components, services and potential, and its implantation in Spain. It consists of thirteen participant countries with eight certified web portals, with another 5 under development and another two thematic ones. In February 2009 Scielo.org had 611 magazines and 195,789 articles of which 46% were about health sciences. Spain became a project member in 1999 and launched the SciELO web portal in 2001, as well as 4 magazines. It currently has 39 titles in the field of Health Sciences; one of which is the Revista Española de Sanidad Penitenciaria, which joined the project in 2007 and which

  13. RSS (http://www.iaees.org/publications/journals/ces/rss.xml

    Directory of Open Access Journals (Sweden)

    Computational Ecology and Software (ISSN 2220-721X

    Full Text Available Computational Ecology and Software ISSN 2220-721X URL: http://www.iaees.org/publications/journals/ces/online-version.asp RSS: http://www.iaees.org/publications/journals/ces/rss.xml E-mail: ces@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope COMPUTATIONAL ECOLOGY AND SOFTWARE (ISSN 2220-721X is an open access, peer-reviewed online journal that considers scientific articles in all different areas of computational ecology. It is the transactions of the International Society of Computational Ecology. The journal is concerned with the ecological researches, constructions and applications of theories and methods of computational sciences including computational mathematics, computational statistics and computer science. It features the simulation, approximation, prediction, recognition, and classification of ecological issues. Intensive computation is one of the major stresses of the journal. The journal welcomes research articles, short communications, review articles, perspectives, and book reviews. The journal also supports the activities of the International Society of Computational Ecology. The topics to be covered by CES include, but are not limited to: •Computation intensive methods, numerical and optimization methods, differential and difference equation modeling and simulation, prediction, recognition, classification, statistical computation (Bayesian computing, randomization, bootstrapping, Monte Carlo techniques, stochastic process, etc., agent-based modeling, individual-based modeling, artificial neural networks, knowledge based systems, machine learning, genetic algorithms, data exploration, network analysis and computation, databases, ecological modeling and computation using Geographical Information Systems, satellite imagery, and other computation intensive theories and methods. •Artificial ecosystems, artificial life, complexity of ecosystems and virtual reality. •The development, evaluation and validation of software and

  14. [SciELO: A cooperative project for the dissemination of science].

    Science.gov (United States)

    Bojo Canales, C; Fraga Medín, C; Hernández Villegas, S; Primo Peña, E

    2009-10-01

    The article describes the SciELO (Scientific Electronic Library Online) model for the electronic publication and dissemination of scientific journals, its origin and evolution, methodology, components, services and potential, and its implantation in Spain. It consists of thirteen participant countries with eight certified web portals, with another 5 under development and another two thematic ones. In February 2009 Scielo.org had 611 magazines and 195,789 articles of which 46% were about health sciences. Spain became a project member in 1999 and launched the SciELO web portal in 2001, as well as 4 magazines. It currently has 39 titles in the field of Health Sciences; one of which is the Revista Española de Sanidad Penitenciaria, which joined the project in 2007 and which currently has 6 issues from 2007 and 2008 available. This makes it one of the most important open access initiatives existing. The report concludes by stating that the SciELO model contributes to the development of research and science by offering an effective and efficient method of promoting and increasing the dissemination of scientific publications in Latin America.

  15. www.elearnSCI.org: a global educational initiative of ISCoS.

    Science.gov (United States)

    Chhabra, H S; Harvey, L A; Muldoon, S; Chaudhary, S; Arora, M; Brown, D J; Biering-Sorensen, F; Wyndaele, J J; Charlifue, S; Horsewell, J; Ducharme, S; Green, D; Simpson, D; Glinsky, J; Weerts, E; Upadhyay, N; Aito, S; Wing, P; Katoh, S; Kovindha, A; Krassioukov, A; Weeks, C; Srikumar, V; Reeves, R; Siriwardane, C; Hasnan, N; Kalke, Y B; Lanig, I

    2013-03-01

    To develop a web-based educational resource for health professionals responsible for the management of spinal cord injury (SCI). The resource:www.elearnSCI.org is comprised of seven learning modules, each subdivided into various submodules. Six of the seven modules address the educational needs of all disciplines involved in comprehensive SCI management. The seventh module addresses prevention of SCI. Each submodule includes an overview, activities, self-assessment questions and references. Three hundred and thirty-two experts from The International Spinal Cord Society (ISCoS) and various affiliated societies from 36 countries were involved in developing the resource through 28 subcommittees. The content of each submodule was reviewed and approved by the Education and Scientific Committees of ISCoS and finally by an Editorial Committee of 23 experts. The content of the learning modules is relevant to students and to new as well as experienced SCI healthcare professionals. The content is applicable globally, has received consumer input and is available at no cost. The material is presented on a website underpinned by a sophisticated content-management system, which allows easy maintenance and ready update of all the content. The resource conforms to key principles of e-learning, including appropriateness of curriculum, engagement of learners, innovative approaches, effective learning, ease of use, inclusion, assessment, coherence, consistency, transparency, cost effectiveness and feedback. www.elearnSCI.org provides a cost effective way of training healthcare professionals that goes beyond the textbook and traditional face-to-face teaching.

  16. Lessons from Afar: A Review of www.daisakuikeda.org, Official Website of Daisaku Ikeda

    Science.gov (United States)

    Arauz, Luis

    2012-01-01

    Daisaku Ikeda (1928- ) is a Buddhist leader, peace builder, school founder, and poet. His own biography and lifework provide a model for how one can transform adversity into alternative opportunities for some of the most disenfranchised students. Scrutinizing Ikeda's official website (www.daisakuikeda.org) reveals an extensive collection of his…

  17. Effect of and satisfaction with www.elearnSCI.org for training of nurse students: a submodule pilot study.

    Science.gov (United States)

    Liu, N; Li, X W; Zhou, M W; Krassioukov, A V; Biering-Sørensen, F

    2014-10-01

    Interventional training session. To investigate the effect and satisfaction with didactic training using printed text of a submodule of www.elearnSCI.org for nurse students and to assess the answers of each question. A Peking University teaching hospital. Twenty-eight nurse students in two groups (14 in each) were involved. Only group A received a translated print-out of the slides from the 'Nursing management' submodule in www.elearnSCI.org for 1-h self-study before the class. At the beginning of class, both groups were tested using the self assessment questions. Then, a lecture according to the content of this submodule was carried out and afterwards both groups answered the self assessment questions again. Finally, both groups filled in a training course satisfaction questionnaire. At the beginning of the class, the mean score (max 9) of the self assessment in group A was 7.1 ± 1.1, which was significantly higher than that in group B (4.9 ± 1.7, P = 0.001). After the lecture, the mean score of the self assessment in group A had insignificantly increased to 7.4 ± 1.3, whereas in group B it increased significantly to 6.9 ± 0.8 (P org to nurse students. The training satisfaction of this submodule within the www.elearnSCI.org is favorable.

  18. Network Biology (http://www.iaees.org/publications/journals/nb/online-version.asp

    Directory of Open Access Journals (Sweden)

    networkbiology@iaees.org

    Full Text Available Network Biology ISSN 2220-8879 URL: http://www.iaees.org/publications/journals/nb/online-version.asp RSS: http://www.iaees.org/publications/journals/nb/rss.xml E-mail: networkbiology@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope NETWORK BIOLOGY (ISSN 2220-8879; CODEN NBEICS is an open access, peer-reviewed international journal that considers scientific articles in all different areas of network biology. It is the transactions of the International Society of Network Biology. It dedicates to the latest advances in network biology. The goal of this journal is to keep a record of the state-of-the-art research and promote the research work in these fast moving areas. The topics to be covered by Network Biology include, but are not limited to: •Theories, algorithms and programs of network analysis •Innovations and applications of biological networks •Ecological networks, food webs and natural equilibrium •Co-evolution, co-extinction, biodiversity conservation •Metabolic networks, protein-protein interaction networks, biochemical reaction networks, gene networks, transcriptional regulatory networks, cell cycle networks, phylogenetic networks, network motifs •Physiological networks •Network regulation of metabolic processes, human diseases and ecological systems •Social networks, epidemiological networks •System complexity, self-organized systems, emergence of biological systems, agent-based modeling, individual-based modeling, neural network modeling, and other network-based modeling, etc. We are also interested in short communications that clearly address a specific issue or completely present a new ecological network, food web, or metabolic or gene network, etc. Authors can submit their works to the email box of this journal, networkbiology@iaees.org. All manuscripts submitted to this journal must be previously unpublished and may not be considered for publication elsewhere at any time during review period of this journal

  19. Environmental Skeptics and Critics (http://www.iaees.org/publications/journals/environsc/online-version.asp

    Directory of Open Access Journals (Sweden)

    environsc@iaees.org

    Full Text Available Environmental Skeptics and Critics ISSN 2224-4263 URL: http://www.iaees.org/publications/journals/environsc/online-version.asp RSS: http://www.iaees.org/publications/journals/environsc/rss.xml E-mail: environsc@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope The more truth is debated, the clearer it becomes. Science will not proceed without debate and controversy. Wide and in-depth debate and controversy on human's knowledge, attitudes, policies and practices on the environment determines the future of our planet. There are numerous controversial and potentially controversial issues on environmental sciences and practices. ENVIRONMENTAL SKEPTICS and CRITICS (ISSN 2224-4263 is an international journal devoted to the publication of skeptical and critical articles/short communications/letters on theories, viewpoints, methodologies, practices, policies, etc., in ecological and environmental areas. The journal provides a forum for questioning, disputing, arguing, challenging, criticizing and judging known theories, methdologies, practices, and policies, etc., or presenting different ideas. The scope of Environmental Skeptics and Critics is wide and embraces all controversial, non-conclusive or unexplained issues in ecological and environmental areas. Authors can submit their works to the email box of this journal, environsc@iaees.org. All manuscripts submitted to this journal must be previously unpublished and may not be considered for publication elsewhere at any time during review period of this journal. Authors are asked to read Author Guidelines before submitting manuscripts. In addition to free submissions from authors around the world, special issues are also accepted. The organizer of a special issue can collect submissions (yielded from a research project, a research group, etc. on a specific research topic, or submissions of a scientific conference for publication of special issue.

  20. Computational Ecology and Software (http://www.iaees.org/publications/journals/ces/online-version.asp

    Directory of Open Access Journals (Sweden)

    ces@iaees.org

    Full Text Available Computational Ecology and Software ISSN 2220-721X URL: http://www.iaees.org/publications/journals/ces/online-version.asp RSS: http://www.iaees.org/publications/journals/ces/rss.xml E-mail: ces@iaees.org Editor-in-Chief: WenJun Zhang Aims and Scope COMPUTATIONAL ECOLOGY AND SOFTWARE (ISSN 2220-721X is an open access, peer-reviewed online journal that considers scientific articles in all different areas of computational ecology. It is the transactions of the International Society of Computational Ecology. The journal is concerned with the ecological researches, constructions and applications of theories and methods of computational sciences including computational mathematics, computational statistics and computer science. It features the simulation, approximation, prediction, recognition, and classification of ecological issues. Intensive computation is one of the major stresses of the journal. The journal welcomes research articles, short communications, review articles, perspectives, and book reviews. The journal also supports the activities of the International Society of Computational Ecology. The topics to be covered by CES include, but are not limited to: •Computation intensive methods, numerical and optimization methods, differential and difference equation modeling and simulation, prediction, recognition, classification, statistical computation (Bayesian computing, randomization, bootstrapping, Monte Carlo techniques, stochastic process, etc., agent-based modeling, individual-based modeling, artificial neural networks, knowledge based systems, machine learning, genetic algorithms, data exploration, network analysis and computation, databases, ecological modeling and computation using Geographical Information Systems, satellite imagery, and other computation intensive theories and methods. •Artificial ecosystems, artificial life, complexity of ecosystems and virtual reality. •The development, evaluation and validation of software and

  1. [SciELO: method for electronic publishing].

    Science.gov (United States)

    Laerte Packer, A; Rocha Biojone, M; Antonio, I; Mayumi Takemaka, R; Pedroso García, A; Costa da Silva, A; Toshiyuki Murasaki, R; Mylek, C; Carvalho Reisl, O; Rocha F Delbucio, H C

    2001-01-01

    It describes the SciELO Methodology Scientific Electronic Library Online for electronic publishing of scientific periodicals, examining issues such as the transition from traditional printed publication to electronic publishing, the scientific communication process, the principles which founded the methodology development, its application in the building of the SciELO site, its modules and components, the tools use for its construction etc. The article also discusses the potentialities and trends for the area in Brazil and Latin America, pointing out questions and proposals which should be investigated and solved by the methodology. It concludes that the SciELO Methodology is an efficient, flexible and wide solution for the scientific electronic publishing.

  2. The influence of question design on the response to self-assessment in www.elearnSCI.org: a submodule pilot study.

    Science.gov (United States)

    Liu, N; Li, X-W; Zhou, M-W; Biering-Sørensen, F

    2015-08-01

    This is an interventional training session. The objective of this study was to investigate the difference in response to self-assessment questions in the original and an adjusted version for a submodule of www.elearnSCI.org for student nurses. The study was conducted in a teaching hospital affiliated to Peking University, China. In all, 28 student nurses divided into two groups (groups A and B; 14 in each) received a print-out of a Chinese translation of the slides from the 'Maintaining skin integrity following spinal cord injury' submodule in www.elearnSCI.org for self-study. Both groups were then tested using the 10 self-assessment multiple-choice questions (MCQs) related to the same submodule. Group A used the original questions, whereas group B received an adjusted questionnaire. The responses to four conventional single-answer MCQs were nearly all correct in both groups. However, in three questions, group A, with the option 'All of the above', had a higher number of correct answers than group B, with multiple-answer MCQs. In addition, in another three questions, group A, using the original multiple-answer MCQs, had fewer correct answers than group B, where it was only necessary to tick a single incorrect answer. Variations in design influence the response to questions. The use of conventional single-answer MCQs should be reconsidered, as they only examine the recall of isolated knowledge facts. The 'All of the above' option should be avoided because it would increase the number of correct answers arrived at by guessing. When using multiple-answer MCQs, it is recommended that the questions asked should be in accordance with the content within the www.elearnSCI.org.

  3. DOI in scientific journals of SciELO portal

    Directory of Open Access Journals (Sweden)

    Sandra Gisela Martín

    2013-10-01

    Full Text Available The research provides a description of the SciELO journals portal and the DOI identifier through its range, year of creation, history, management, policy, structure, ISBN-A and reference sources. It provides information on the implementation of the DOI in citations styles APA and Vancouver, and standards ISO 690-2010 and ABNT6023-2002. The work aimed to explore the degree of implementation of the DOI in scientific journals in SciELO, identify where DOI display, knowing the amount of publishers as DOI prefix, determine the number of journals titles including the ISSN suffix code and identify the degree of implementation of the DOI in the styles and standards of citations available in SciELO. Descriptive methodology was applied where data were collected through direct observation of the websites of the 898 current journals available between the months of December 2012 and January 2013 in SciELO portal. It concludes that less than 50% of the countries in SciELO are currently using the DOI in its publications, primarily displayed code in HTML files, only 30 of the 929 publishers implemented it and most include the ISSN identifier within the suffix. While using the DOI in all citations of the articles, not does so strict as the provisions of the rules and styles.

  4. Alzheimer's Prevention Education: If We Build It, Will They Come? www.AlzU.org.

    Science.gov (United States)

    Isaacson, R S; Haynes, N; Seifan, A; Larsen, D; Christiansen, S; Berger, J C; Safdieh, J E; Lunde, A M; Luo, A; Kramps, M; McInnis, M; Ochner, C N

    2014-01-01

    Internet-based educational interventions may be useful for impacting knowledge and behavioral change. However, in AD prevention, little data exists about which educational tools work best in terms of learning and interest in participating in clinical trials. Primary: Assess effectiveness of interactive webinars vs. written blog-posts on AD prevention learning. Secondary: Evaluate the effect of AD prevention education on interest in participating in clinical trials; Assess usability of, and user perceptions about, an online AD education research platform; Classify target populations (demographics, learning needs, interests). Observational. Online. Men/Women, aged 25+, recruited via facebook.com. Alzheimer's Universe (www.AlzU.org) education research platform. Pre/post-test performance, self-reported Likert-scale ratings, completion rates. Over two-weeks, 4268 visits were generated. 503 signed-up for a user account (11.8% join rate), 196 participated in the lessons (39.0%) and 100 completed all beta-testing steps (19.9%). Users randomized to webinar instruction about AD prevention and the stages of AD demonstrated significant increases (p=0.01) in pre vs. post-testing scores compared to blog-post intervention. Upon joining, 42% were interested in participating in a clinical trial in AD prevention. After completing all beta-test activities, interest increased to 86%. Users were primarily women and the largest category was children of AD patients. 66.3% joined to learn more about AD prevention, 65.3% to learn more about AD treatment. Webinar-based education led to significant improvements in learning about AD prevention and the stages of AD. AlzU.org participation more than doubled interest in AD prevention clinical trial participation. Subjects were quickly and cost-effectively recruited, and highly satisfied with the AD education research platform. Based on these data, we will further refine AlzU.org prior to public launch and aim to study the effectiveness of 25

  5. Aporte estudiantil en la publicación de artículos científicos en revistas médicas indizadas en Scielo-Perú, 1997 - 2005

    Directory of Open Access Journals (Sweden)

    Charles Huamaní

    2008-03-01

    Full Text Available Objetivo: Cuantificar la participación estudiantil en la publicación de artículos originales en revistas médicas peruanas indizadas a SciELO Perú. Diseño: Estudio observacional retrospectivo. Lugar: Hemeroteca de la Facultad de Medicina UNMSM y en www.scielo.org.pe. Población: Artículos originales, comunicaciones cortas (incluye casos clínicos y cartas al editor publicadas en volúmenes correspondientes a 1997 hasta 2005, en revistas de periodicidad trimestral actualizadas. Intervenciones: Revisión de la filiación de los autores (estudiante o profesional; sexo, universidad y carrera de procedencia, tipo de artículo y área de investigación (clínica, biomédica y salud pública. Principales resultados: Frecuencia y porcentaje de artículos con participación estudiantil. Resultados: Se incluyó 865 contribuciones originales de cuatro revistas; en 4,5% (39 de ellas hubo participación estudiantil en la autoría, 74% (29/39 fueron artículos originales, 10 comunicaciones cortas y ninguna carta al editor. Anales de la Facultad de Medicina fue la revista que publicó más artículos estudiantiles (6,6%. La mediana fue de cinco artículos estudiantiles por año. Diez artículos fueron realizados solo por estudiantes, 87% procedía de tres universidades (Universidad Nacional Mayor de San Marcos, Universidad Peruana Cayetano Heredia y Universidad Privada Antenor Orrego y 58%, del área clínica. La mayoría (72% de los autores fue varón. Conclusiones: La participación estudiantil en la publicación de artículos en revistas médicas peruanas indizadas en SciELO Perú es baja. Se recomienda capacitar a los estudiantes en la publicación de sus investigaciones, incluyendo cursos o tópicos en la formación médica universitaria.

  6. DLSanalysis.org

    DEFF Research Database (Denmark)

    Hansen, Steen

    2017-01-01

    A web interface ( www.DLSanalysis.org ) for indirect Laplace transformation of dynamic light scattering data is presented. When experimental data are uploaded to the server they are processed in a few seconds, and the result is displayed on the screen in the form of a size distribution together...

  7. CORSiCA Atmospheric Observatory: Intense activities in 2012 in the frame of HyMeX and ChArMEx

    Science.gov (United States)

    Lambert, Dominique

    2013-04-01

    In the western Mediterranean basin, Corsica Island is at a strategic location for atmospheric studies in the framework of the Mediterranean projects HyMeX (Hydrological Mediterranean Experiment; http://www.hymex.org/) and ChArMEx (the Chemistry-Aerososl MEditerranean Experiment; http://charmex.lsce.ipsl.fr/) developped under the umbrella of the programme MISTRALS (Mediterranean Integrated Studies at Regional and Local Scales; http://www.mistrals-home.org). The development of a multi-sites instrumented platform located on this island is the core of the project CORSiCA (Corsican Observatory for Research and Studies on Climate and Atmosphere-ocean environment). CORSiCA is operated in the framework of the HyMEx and ChArMEx Long Observation Period (LOP), Enhanced Observation Period (EOP) and Special Observation Periods (SOP). In the present communication we will focus on the scientific objectives and describe the diversity of observations that have been performed by many institutes in Corsica in the frame of 2012 campaigns including HyMeX Special Observation Period 1 in autumn, ChArMEx pre-campaign and VESSAER in summer. Results from these campaigns will be illustrated and projects for future campaign activities and long-term monitoring in the framework of the CORSiCA Atmospheric Observatory will be presented (more details can be found in other more specific presentations). Acknowledgements are addressed to campaigns main sponsors: HyMeX: Météo-France, INSU, KIT; pre-ChArMEx: INSU, ADEME, CEA; VESSAER: FP7/Infrastructures/EUFAR, COST, Météo-France. The development of the CORSiCA platform is supported by Collectivité Territoriale de Corse (CPER) and EU FEDER funds.

  8. Sustainability of Latin American initiatives that publish open access journals using the XML-JATS standard: the case SciELO

    Directory of Open Access Journals (Sweden)

    Eliana Guzmán-Useche

    2016-11-01

    Full Text Available Objectives: It is performed a sustainability analysis of the Latin American initiative scielo.org based on two main aspects, the economic and the need for its existence. Method: To achieve that, the required man-hours to publish a scientific paper were measured, using its new publication methodology called XML SPS. 40 articles published in scientific journals of different areas of knowledge are processed; journals from Brazil, Chile, Colombia, Mexico and Venezuela, using that methodology. Results showed that the preparation of the document takes on average 35% of the total time (σ = 9.72%, while the tagging process takes on average 50% of the time (σ = 8.50%, finally the sections corresponding to references, acknowledgments and appendices (back takes the majority of the time. Conclusions: This analysis indicates that the SciELO publishing model is sustainable from the point of view of the need for its existence, but in the economic terms seems not to be fully sustainable for all countries in the region, because it is a technically complex process that not all publishers are able to perform, making outsourcing of that procedure to be necessary, which requires a greater budget for the journal that can jeopardize the sustainability and the control of this publishing model.

  9. New international ways in radiology continuing education: www.eurorad.org - an EAR project for online publication of radiological data

    International Nuclear Information System (INIS)

    Vorwerk, D.

    2002-01-01

    Eurorad (www.eurorad.org) is a joint project of EAR and has support of 27 national and 8 subspeciality radiology societies. Eurorad is the first noncommercial radiologicial publication that is exclusively based on the internet as a communication line with all steps of submission, reviewing and publication being performed online. Eurorad wants to build up a huge and exhaustive case file of diagnostic and interventional radiology. Like all scientific publications, Eurorad bases on an editor in chief and 13 section editors who are responsible for organizing each section of Eurorad. Each section has a number of peer reviewer with an overall total of more than 100. For submission and publication, all cases are structured in the same manner with case report, method and discussion. For the time being, Eurorad hosts 779 cases, of whom 346 are free available on the net. The actual rejection rate is 4.5%, other cases are under review. (orig.) [de

  10. A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO).

    Science.gov (United States)

    de Souza, Raphael Freitas; Chaves, Carolina de Andrade Lima; Nasser, Mona; Fedorowicz, Zbys

    2010-01-01

    Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which provide open access to full-text articles.This library includes a number of dental journals some of which may include reports of clinical trials in English, Portuguese and/or Spanish. Thus, SciELO could play an important role as a source of evidence for dental healthcare interventions especially if it yields a sizeable number of high quality reports. The aim of this study was to identify reports of clinical trials by handsearching of dental journals that are accessible through SciELO, and to assess the overall quality of these reports. Electronic versions of six Brazilian dental Journals indexed in SciELO were handsearched at www.scielo.br in September 2008. Reports of clinical trials were identified and classified as controlled clinical trials (CCTs - prospective, experimental studies comparing 2 or more healthcare interventions in human beings) or randomized controlled trials (RCTs - a random allocation method is clearly reported), according to Cochrane eligibility criteria. CRITERIA TO ASSESS METHODOLOGICAL QUALITY INCLUDED: method of randomization, concealment of treatment allocation, blinded outcome assessment, handling of withdrawals and losses and whether an intention-to-treat analysis had been carried out. The search retrieved 33 CCTs and 43 RCTs. A majority of the reports provided no description of either the method of randomization (75.3%) or concealment of the allocation sequence (84.2%). Participants and outcome assessors were reported as blinded in only 31.2% of the reports. Withdrawals and losses were only clearly described in 6.5% of the reports and none mentioned an intention-to-treat analysis or any similar procedure. The results of this study indicate that a substantial number of reports of trials and systematic

  11. AR copy number and AR signaling-directed therapies in castration-resistant prostate cancer.

    Science.gov (United States)

    Salvi, Samanta; Conteduca, Vincenza; Lolli, Cristian; Testoni, Sara; Casadio, Valentina; Zaccheroni, Andrea; Rossi, Lorena; Burgio, Salvatore Luca; Menna, Cecilia; Schepisi, Giuseppe; De Giorgi, Ugo

    2017-11-22

    Adaptive upregulation of androgen receptor (AR) is the most common event involved in the progression from hormone sensitive to castration-resistant prostate cancer (CRPC). AR signaling remains the main target of new AR signalling-directed therapies such as abiraterone and enzalutamide in CRPC patients. In this review, we discuss general mechanisms of resistance to AR-targeted therapies, with a focus on the role of AR copy number (CN). We reported methods and clinical applications of AR CN evaluation in tissue and liquid biopsy, thus to have a complete information regarding its role as predictive and prognostic biomarker. Outcomes of CRPC patients are reported to be highly variable as consequence of tumor heterogeneity. AR CN could contribute to patient selection and tumor monitoring in CRPC treated with new anti-cancer treatment as abiraterone and enzalutamide. Further studies to investigate AR CN effect to these agents and its potential combination with other prognostic or predictive clinical factors are necessary in the context of harmonized clinical trial design. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  12. A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO

    Directory of Open Access Journals (Sweden)

    Raphael Freitas de Souza

    2010-04-01

    Full Text Available INTRODUCTION: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which provide open access to full-text articles.This library includes a number of dental journals some of which may include reports of clinical trials in English, Portuguese and/or Spanish. Thus, SciELO could play an important role as a source of evidence for dental healthcare interventions especially if it yields a sizeable number of high quality reports. OBJECTIVE: The aim of this study was to identify reports of clinical trials by handsearching of dental journals that are accessible through SciELO, and to assess the overall quality of these reports. MATERIAL AND METHODS: Electronic versions of six Brazilian dental Journals indexed in SciELO were handsearched at www.scielo.br in September 2008. Reports of clinical trials were identified and classified as controlled clinical trials (CCTs - prospective, experimental studies comparing 2 or more healthcare interventions in human beings or randomized controlled trials (RCTs - a random allocation method is clearly reported, according to Cochrane eligibility criteria. CRITERIA TO ASSESS METHODOLOGICAL QUALITY INCLUDED: method of randomization, concealment of treatment allocation, blinded outcome assessment, handling of withdrawals and losses and whether an intention-to-treat analysis had been carried out. RESULTS: The search retrieved 33 CCTs and 43 RCTs. A majority of the reports provided no description of either the method of randomization (75.3% or concealment of the allocation sequence (84.2%. Participants and outcome assessors were reported as blinded in only 31.2% of the reports. Withdrawals and losses were only clearly described in 6.5% of the reports and none mentioned an intention-to-treat analysis or any similar procedure. CONCLUSIONS: The results of

  13. Impact of SciELO and MEDLINE indexing on submissions to Jornal de Pediatria.

    Science.gov (United States)

    Blank, Danilo; Buchweitz, Claudia; Procianoy, Renato S

    2005-01-01

    To evaluate the impact of SciELO and MEDLINE indexing on the number of articles submitted to Jornal de Pediatria. Analysis of total article submission, submission of articles from foreign countries and acceptance figures in the following periods: stage I - pre-website (Jan 2000-Mar 2001); stage II - website (Apr 2001-Jul 2002); stage III - SciELO (Aug 2002-Aug 2003); stage IV - MEDLINE (Sep 2003-Dec 2004). There was a significant trend toward linear increase in the number of submissions along the study period (p = 0.009). The number of manuscripts submitted in stages I through IV was 184, 240, 297, and 482, respectively. The number of submissions was similar in stages I and II (p = 0.148), but statistically higher in Stage III (p SciELO indexing was associated with an increase in Brazilian manuscript submissions to Jornal de Pediatria, whereas MEDLINE indexing led to an increase in both Brazilian and foreign submissions.

  14. Ranking Business and Economics Journals in South America Using the Scientific Electronic Library Online (SciELO)

    Science.gov (United States)

    Alexander, Jennifer K.; Pradenas, Lorena; Parada, Victor; Scherer, Robert F.

    2012-01-01

    Access to published research for knowledge creation and education in the administrative science disciplines in South America has been enhanced since the introduction of the Scientific Electronic Library Online (SciELO). Although SciELO has been available as an online journal indexing and publication service since 1998, there have been no…

  15. Thanks to 70 years of Inter American Statistical cooperation, the world's largest integrated census microdata dissemination site www.ipums.org/international.

    Science.gov (United States)

    McCAA, Robert

    2013-06-01

    Seventy years of Inter American Statistical cooperation, symbolized by the 70 th anniversary of Estadística , made possible the construction of IPUMS-International, the world's largest integrated census microdata dissemination site, www.ipums.org/international. Currently, the site offers access to 238 samples totaling over 540 million person records representing 74 countries. The Americas, which account for only about one-seventh of the world's population, amount to over one-third (36%) of the person records in the IPUMS-International database. Likewise, 35% of the citations in the IPUMS-International bibliography are for studies focused on Latin America, with about half of these analyzing a single Latin American country. This article discusses salient features of the IPUMS integration methods and system. National Statistical Institutes that have not yet entrusted 2010 census microdata to the initiative are invited to do so. Researchers and teachers are invited to use the data freely in analysis and teaching. Setenta años de cooperación estadística inter-Americana, simbolizada por el 70 aniversario de la revista Estadística , han hecho posible la construcción de IPUMS-internacional, la base en línea de microdatos censales harmonizados más grande del mundo, www.ipums.org/international. Actualmente, IPUMS proporciona acceso a 238 muestras con más de 540 millones de registros individuales de 74 países. Las Américas, que albergan una séptima parte de la población mundial, representan más de un tercio (36%) de todos los registros individuales en la base de datos IPUMS-internacional. Asimismo, el 35% de todas las referencias en la bibliografía de IPUMS son de estudios realizados sobre América Latina, la mitad de éstas basadas en un sólo país de la región. Este artículo presenta las principales características del sistema de integración y difusión de datos de IPUMS. Los Institutos Nacionales de Estadísticas que todavía no ha entregado la muestra

  16. Mis on looming.org? : elektrooniline heli / Andres Lõo

    Index Scriptorium Estoniae

    Lõo, Andres

    2004-01-01

    Võrguajakirjast www.looming.org, kuhu kogutakse infot põhiliselt kahe jaotuse põhjal: muusika ja helieksperimentalism ning kaasaegne kunst, kunsti ja meediaga seonduv. Idee autorid: Hanno Soans ja Andres Lõo. Ilmunud on looming.orgi esimene muusikakogumik "Lilled algebrale"

  17. IPM strategies and their dilemmas including an introduction to www.Eurowheat.org

    DEFF Research Database (Denmark)

    Jørgensen, Lise Nistrup; Hovmøller, Mogens Støvring; Hansen, Jens Grønbech

    2014-01-01

    Information about disease management in winter wheat (Triticum aestiva) in eight European countries was collated and analysed by scientists and extension workers within a European Network for Durable Exploitation (ENDURE). This included information about specific disease thresholds, decision...... information platformwww.EuroWheat.org was used for dissemination of information and results including information on control thresholds, cultural practices which can influence disease attack, fungicide efficacy, fungicide resistance and pathogen virulence, which are all elements supporting IPM for disease...... control in wheat. The platform is open to all users. The target groups of EuroWheat information are researchers, advisors, breeders and similar partners dealing with disease management in wheat....

  18. Thanks to 70 years of Inter American Statistical cooperation, the world’s largest integrated census microdata dissemination site www.ipums.org/international

    Science.gov (United States)

    McCAA, ROBERT

    2014-01-01

    Seventy years of Inter American Statistical cooperation, symbolized by the 70th anniversary of Estadística, made possible the construction of IPUMS-International, the world’s largest integrated census microdata dissemination site, www.ipums.org/international. Currently, the site offers access to 238 samples totaling over 540 million person records representing 74 countries. The Americas, which account for only about one-seventh of the world’s population, amount to over one-third (36%) of the person records in the IPUMS-International database. Likewise, 35% of the citations in the IPUMS-International bibliography are for studies focused on Latin America, with about half of these analyzing a single Latin American country. This article discusses salient features of the IPUMS integration methods and system. National Statistical Institutes that have not yet entrusted 2010 census microdata to the initiative are invited to do so. Researchers and teachers are invited to use the data freely in analysis and teaching. Setenta años de cooperación estadística inter-Americana, simbolizada por el 70 aniversario de la revista Estadística, han hecho posible la construcción de IPUMS-internacional, la base en línea de microdatos censales harmonizados más grande del mundo, www.ipums.org/international. Actualmente, IPUMS proporciona acceso a 238 muestras con más de 540 millones de registros individuales de 74 países. Las Américas, que albergan una séptima parte de la población mundial, representan más de un tercio (36%) de todos los registros individuales en la base de datos IPUMS-internacional. Asimismo, el 35% de todas las referencias en la bibliografía de IPUMS son de estudios realizados sobre América Latina, la mitad de éstas basadas en un sólo país de la región. Este artículo presenta las principales características del sistema de integración y difusión de datos de IPUMS. Los Institutos Nacionales de Estadísticas que todavía no ha entregado la muestra

  19. WWW.CDI-CLEX.ORG

    DEFF Research Database (Denmark)

    Jørgensen, Rune Nørgaard; Dale, Philip; Bleses, Dorthe

    2011-01-01

    Parent report has proven a valid and cost-effective means of evaluating early child language. Large scale datasets has proven to be useful both when it comes to basic research as well as in relation to assessment and intervention. And since norming studies based on parent reports contains great...

  20. The SciELO Open Access: A Gold Way from the South

    Science.gov (United States)

    Packer, Abel L.

    2009-01-01

    Open access has long emphasized access to scholarly materials. However, open access can also mean access to the means of producing visible and recognized journals. This issue is particularly important in developing and emergent countries. The SciELO (Scientific Electronic Library On-line) project, first started in Brazil and, shortly afterward, in…

  1. The about consumer behavior in SciELO

    Directory of Open Access Journals (Sweden)

    Dhione Oliveira Santana

    2016-05-01

    Full Text Available Studies of consumer behavior have called the attention of researchers from different countries and different areas of expertise with the objectives as varied as possible. This article is an interdisciplinary bibliometric study on consumer behavior in the international context (Ibero - American countries and South Africa SciELO (ScientificElectronic Library Online platform. This study examined 153 scientific articles, as a conclusion it was observed that the main research come from the applied social sciences and humanities, with a predominance of the administration area, an area that also holds the most scientific publications, noted also that there is a predominance of texts from a university or even a group of research and empirical studies that dominate the landscape of publications.

  2. Seeing the doctor without fear: www.doctortea.org for the desensitization for medical visits in Autism Spectrum Disorders.

    Science.gov (United States)

    Boada, Leticia; Parellada, Mara

    Doctor Tea is an online website designed to facilitate medical visits for those with autism spectrum disorder and other disabilities. People diagnosed with autism not only have greater medical needs than the general population, but also have particular characteristics that are often not accommodated by medical services. This lack of medical accommodation often creates a very complicated, and sometimes traumatic experience, when visiting medical facilities. Individuals with autism have great difficulty understanding social situations and contexts, such as medical tests or consultations, as well as difficulty in tolerating new situations and atypical sensory thresholds. Doctor Tea aims to reduce anxiety before medical consultations and procedures from a safe and well-known environment (school, home, etc.). The website, www.doctortea.org, provides information and materials (videos, cartoon, 3D animations, pictogram sequences, etc.) about the most frequent medical procedures and practices for patients with autism. The website also offers information to the doctors and families of patients with autism about the most common medical problems associated with autism. A total of 17,199 different users visited the website during 2015, with a total of 23,348 online visitors from more than 70 different countries since the website's release in November 2014. The familiarisation with the medical procedures and its environment appears to decrease the anxiety in patients with disabilities during medical visits, as well as optimising the effectiveness of their medical visits and tests. Copyright © 2016 SEP y SEPB. Publicado por Elsevier España, S.L.U. All rights reserved.

  3. DOI in scientific journals of SciELO portal

    OpenAIRE

    Martín, Sandra Gisela

    2013-01-01

    Se presenta una descripción del portal de revistas científicas SciELO y del identificador DOI a través de su alcance, año de creación, historia, administración, normativa, estructura, ISBN-A y fuentes de consulta. Se brinda información acerca de la aplicación del DOI en las citas bibliográficas: en los estilos APA y Vancouver y en las normas ISO 690 (ISO, 2010) y ABNT 6023 (ABNT, 2002). El trabajo se propuso explorar el grado de implementación del DOI en las revistas científicas disponibles e...

  4. Siete sitios webs nuevos en el Directorio de Webs Amigas de Veterinaria.org

    OpenAIRE

    Veterinaria.org

    2009-01-01

    ResumenOcho sitios webs – AVAFES Zaragoza, Dermoveterinaria, International Veterinary StudentsAssociation, Oceonágrafos Sin Fronteras, Oftalmología Veterinaria, Pujol Torguet, Sea Wolves y Veterinaria Igfranvet - se han incorporado durante el pasado mes de febrero 2009 al Directorio de Web Amigas de Veterinaria.org tal como se puede comprobar visitando http://www.veterinaria.org/wamigas/l_amigas.html

  5. Condicionamento de ar em salas de operação e controle de infecção - uma revisão

    Directory of Open Access Journals (Sweden)

    May Socorro Martinez Afonso

    2006-04-01

    Full Text Available Revisão bibliográfica, realizada junto aos bancos de dados MED LINE, LILACS, SCIELO, Ministério da Saúde e outros buscadores, com o objetivo de identificar os fatores que torna o ar condicionado fonte de contaminação ambiental. O ar é contaminado por partículas que transportam microrganismos. As fontes de partículas incluem pacientes e equipe cirúrgica. O controle da temperatura, umidade relativa, pressão, número de trocas de ar realizadas por hora, paramentação, tráfego, número de pessoas nas salas e manutenção e limpeza do sistema de ar condicionado dos centros cirúrgicos, são fatores importantes na redução do número de microrganismos no ambiente de sala de operação.

  6. Immune epitope database analysis resource (IEDB-AR)

    DEFF Research Database (Denmark)

    Zhang, Qing; Wang, Peng; Kim, Yohan

    2008-01-01

    We present a new release of the immune epitope database analysis resource (IEDB-AR, http://tools.immuneepitope.org), a repository of web-based tools for the prediction and analysis of immune epitopes. New functionalities have been added to most of the previously implemented tools, and a total...

  7. SciELO, Scientific Electronic Library Online, a Database of Open Access Journals

    Science.gov (United States)

    Meneghini, Rogerio

    2013-01-01

    This essay discusses SciELO, a scientific journal database operating in 14 countries. It covers over 1000 journals providing open access to full text and table sets of scientometrics data. In Brazil it is responsible for a collection of nearly 300 journals, selected along 15 years as the best Brazilian periodicals in natural and social sciences.…

  8. Usage of the www.2aida.org AIDA diabetes software Website: a pilot study.

    Science.gov (United States)

    Lehmann, Eldon D

    2003-01-01

    AIDA is a diabetes-computing program freely available from www.2aida.org on the Web. The software is intended to serve as an educational support tool, and can be used by anyone who has an interest in diabetes, whether they be patients, relatives, health-care professionals, or students. In previous "Diabetes Information Technology & WebWatch" columns various indicators of usage of the AIDA program have been reviewed, and various comments from users of the software have been documented. One aspect of AIDA, though, that has been of considerable interest has been to investigate its Web-based distribution as a wider paradigm for more general medically related usage of the Internet. In this respect we have been keen to understand in general terms: (1) why people are turning to the Web for health-care/diabetes information; (2) more specifically, what sort of people are making use of the AIDA software; and (3) what benefits they feel might accrue from using the program. To answer these types of questions we have been conducting a series of audits/surveys via the AIDA Website, and via the software program itself, to learn as much as possible about who the AIDA end users really are. The rationale for this work is that, in this way, it should be possible to improve the program as well as tailor future versions of the software to the interests and needs of its users. However, a recurring observation is that data collection is easiest if it is as unobtrusive and innocuous as possible. One aspect of learning as much as possible about diabetes Website visitors and users may be to apply techniques that do not necessitate any visitor or user interaction. There are various programs that can monitor what pages visitors are viewing at a site. As these programs do not require visitors to do anything special, over time some interesting insights into Website usage may be obtained. For the current study we have reviewed anonymous logstats data, which are automatically collected at many

  9. www.common-metrics.org: a web application to estimate scores from different patient-reported outcome measures on a common scale.

    Science.gov (United States)

    Fischer, H Felix; Rose, Matthias

    2016-10-19

    Recently, a growing number of Item-Response Theory (IRT) models has been published, which allow estimation of a common latent variable from data derived by different Patient Reported Outcomes (PROs). When using data from different PROs, direct estimation of the latent variable has some advantages over the use of sum score conversion tables. It requires substantial proficiency in the field of psychometrics to fit such models using contemporary IRT software. We developed a web application ( http://www.common-metrics.org ), which allows estimation of latent variable scores more easily using IRT models calibrating different measures on instrument independent scales. Currently, the application allows estimation using six different IRT models for Depression, Anxiety, and Physical Function. Based on published item parameters, users of the application can directly estimate latent trait estimates using expected a posteriori (EAP) for sum scores as well as for specific response patterns, Bayes modal (MAP), Weighted likelihood estimation (WLE) and Maximum likelihood (ML) methods and under three different prior distributions. The obtained estimates can be downloaded and analyzed using standard statistical software. This application enhances the usability of IRT modeling for researchers by allowing comparison of the latent trait estimates over different PROs, such as the Patient Health Questionnaire Depression (PHQ-9) and Anxiety (GAD-7) scales, the Center of Epidemiologic Studies Depression Scale (CES-D), the Beck Depression Inventory (BDI), PROMIS Anxiety and Depression Short Forms and others. Advantages of this approach include comparability of data derived with different measures and tolerance against missing values. The validity of the underlying models needs to be investigated in the future.

  10. (www.publiclibraryofscience.org) to foster

    African Journals Online (AJOL)

    denise

    electronic or otherwise) without the express permission of the publishers. tradition, as he explores the topic in relation to research and psychotherapeutic interventions. In his synthetic review, he reminds the reader of such fundamentals as psychology representing the “speech of the soul” and the aspirations of the discipline ...

  11. "MTA"-an Hydraulic Silicate Cement: review update and setting reaction.

    Science.gov (United States)

    Darvell, B W; Wu, R C T

    2011-05-01

    To review the current status and understanding of Portland cement-like endodontic materials commonly referred to by the trade designation "MTA" (alias "Mineral Trioxide Aggregate"), and to present an outline setting reaction scheme, hitherto unattempted. The literature was searched using on-line tools, overlapping an earlier substantial review to pick up any omissions, including that in respect of ordinary Portland cement (OPC), with which MTA shares much. The search was conducted for the period January 2005 to December 2009 using 'MTA', 'GMTA', 'WMTA', and 'mineral AND trioxide AND aggregate' as keywords, with various on-line search engines including ScienceDirect (http://www.sciencedirect.com), SAGE Journals Online (http://online.sagepub.com), Wiley Online Library (http://onlinelibrary.wiley.com), SciELO Scientific electronic library online (http://www.scielo.br/scielo.php), JSTOR (http://www.jstor.org), and Scopus (http://www.scopus.com). References of articles found were cross-checked where appropriate for missed publications. Manufacturers' and related websites were searched with Google Search (http://www.google.com.hk). A generic name for this class of materials, Hydraulic Silicate Cement (HSC), is proposed, and an outline reaction scheme has been deduced. HSC has distinct advantages apparent, including sealing, sterilizing, mineralizing, dentinogenic and osteogenic capacities, which research continues to demonstrate. However, ad hoc modifications have little supporting justification. While HSC has a definite place in dentistry, with few of the drawbacks associated with other materials, some improvements in handling and other properties are highly desirable, as are studies of the mechanisms of the several beneficial physiological effects. Reference to the extensive, but complex, literature on OPC may provide the necessary insight. Copyright © 2011 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  12. Sustentabilidad de la caficultura orgánica en La Convención Cusco

    OpenAIRE

    Marquez Romero, Fanny Rosario

    2015-01-01

    Universidad Nacional Agraria La Molina. Escuela de Posgrado. Doctorado en Agricultura Sustentable Con la finalidad de determinar la sustentabilidad de la caficultura orgánica en La Convención-Cusco se evaluó de forma comparativa la sostenibilidad de la producción de café arábico a nivel social, ambiental y económico del sistema orgánico y convencional, mediante indicadores estratégicos. La zona de estudio se encuentra en la ceja de selva del sur oeste del Perú. Se ha utilizado el método p...

  13. CitSci.org: A New Model for Managing, Documenting, and Sharing Citizen Science Data.

    Directory of Open Access Journals (Sweden)

    Yiwei Wang

    2015-10-01

    Full Text Available Citizen science projects have the potential to advance science by increasing the volume and variety of data, as well as innovation. Yet this potential has not been fully realized, in part because citizen science data are typically not widely shared and reused. To address this and related challenges, we built CitSci.org (see www.citsci.org, a customizable platform that allows users to collect and generate diverse datasets. We hope that CitSci.org will ultimately increase discoverability and confidence in citizen science observations, encouraging scientists to use such data in their own scientific research.

  14. CitSci.org: A New Model for Managing, Documenting, and Sharing Citizen Science Data.

    Science.gov (United States)

    Wang, Yiwei; Kaplan, Nicole; Newman, Greg; Scarpino, Russell

    2015-10-01

    Citizen science projects have the potential to advance science by increasing the volume and variety of data, as well as innovation. Yet this potential has not been fully realized, in part because citizen science data are typically not widely shared and reused. To address this and related challenges, we built CitSci.org (see www.citsci.org), a customizable platform that allows users to collect and generate diverse datasets. We hope that CitSci.org will ultimately increase discoverability and confidence in citizen science observations, encouraging scientists to use such data in their own scientific research.

  15. Impacto da indexação no SciELO e MEDLINE sobre as submissões ao Jornal de Pediatria Impact of SciELO and MEDLINE indexing on submissions to Jornal de Pediatria

    Directory of Open Access Journals (Sweden)

    Danilo Blank

    2005-12-01

    Full Text Available OBJETIVO: Avaliar o impacto da indexação no SciELO e MEDLINE sobre o número de artigos submetidos ao Jornal de Pediatria. MÉTODOS: Análise do total de artigos submetidos, artigos estrangeiros submetidos e índices de aceitação, nos seguintes períodos: estágio I - pré-site (janeiro/2000-março/2001; estágio II - site (abril/2001-julho/2002; estágio III - SciELO (agosto/2002-agosto/2003; estágio IV - MEDLINE (setembro/2003-dezembro/2004. RESULTADOS: Houve uma tendência significativa de aumento linear no número de submissões, durante o período do estudo (p = 0,009. O número de originais submetidos nos estágios I a IV foi, respectivamente: 184, 240, 297 e 482. O número de submissões foi similar nos estágios I e II (p = 0,148, mas foi significativamente maior no estágio III (p OBJECTIVE: To evaluate the impact of SciELO and MEDLINE indexing on the number of articles submitted to Jornal de Pediatria. METHODS: Analysis of total article submission, submission of articles from foreign countries and acceptance figures in the following periods: stage I - pre-website (Jan 2000-Mar 2001; stage II - website (Apr 2001-Jul 2002; stage III - SciELO (Aug 2002-Aug 2003; stage IV - MEDLINE (Sep 2003-Dec 2004. RESULTS: There was a significant trend toward linear increase in the number of submissions along the study period (p = 0.009. The number of manuscripts submitted in stages I through IV was 184, 240, 297, and 482, respectively. The number of submissions was similar in stages I and II (p = 0.148, but statistically higher in Stage III (p < 0.001 vs. Stage I and p = 0.006 vs. Stage II and Stage IV (p < 0.001 vs. stages I and II, and p < 0.05 vs. stage III. The rate of article acceptance decreased during the study period. The number of original articles published has been stable since the 2001 March/April issue (n = 10, when the journal reached a printed page limit, leading to stricter judgment criteria and a relative decrease in acceptance

  16. The new Mediterranean background monitoring station of Ersa, Cape Corsica: A long term Observatory component of the Chemistry-Aerosol Mediterranean Experiment (ChArMEx)

    Science.gov (United States)

    Dulac, Francois

    2013-04-01

    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, http://charmex.lsce.ipsl.fr/) is a French initiative supported by the MISTRALS program (Mediterranean Integrated Studies at Regional And Locals Scales, http://www.mistrals-home.org). It aims at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The major stake is an understanding of the future of the Mediterranean region in a context of strong regional anthropogenic and climatic pressures. The target of ChArMEx is short-lived particulate and gaseous tropospheric trace species which are the cause of poor air quality events, have two-way interactions with climate, or impact the marine biogeochemistry. In order to fulfill these objectives, important efforts have been put in 2012 in order to implement the infrastructure and instrumentation for a fully equipped background monitoring station at Ersa, Cape Corsica, a key location at the crossroads of dusty southerly air masses and polluted outflows from the European continent. The observations at this station began in June 2012 (in the context of the EMEP / ACTRIS / PEGASOS / ChArMEx campaigns). A broad spectrum of aerosol properties is also measured at the station, from the chemical composition (off-line daily filter sampling in PM2.5/PM10, on-line Aerosol Chemical Speciation Monitor), ground optical properties (extinction/absorption/light scattering coeff. with 1-? CAPS PMex monitor, 7-? Aethalometer, 3-? Nephelometer), integrated and vertically resolved optical properties (4-? Cimel sunphotometer and LIDAR, respective), size distribution properties (N-AIS, SMPS, APS, and OPS instruments), mass (PM1/PM10 by TEOM/TEOM-FDMS), hygroscopicity (CCN), as well as total insoluble deposition. So far, real-time measurement of reactive gases (O3, CO, NO, NO2), and off-line VOC measurements (cylinders, cartridges) are also

  17. Anthropometric indicators of abdominal obesity: review of the papers indexed on SciELO electronic library

    Directory of Open Access Journals (Sweden)

    Claudio Barnabé dos Santos Cavalcanti

    2009-01-01

    Full Text Available http://dx.doi.org/10.5007/1980-0037.2009v11n2p217   A systematic review of original articles published between 1993 and 2007 and indexed in SciELO (Scientific Electronic Library Online was carried out to identify the anthropometric indicators used to assess abdominal obesity in different target subgroups, and to provide an overview of available evidence regarding the relationship between these anthropometric indicators and obesity-associated comorbidities. The articles were analyzed and the following data were collected:year of publication, sample size and age, anthropometric measure used to detect abdominal obesity, and main results of the study. The review comprised 47 articles which met all inclusion criteria, most of them published over the last 5 years. Waist-hip ratio and waist circumference were used as indicators of abdominal obesity in 34 and 11 of the articles reviewed, respectively. With respect to age range, the samples were heterogeneous in most of the studies (n=27 and ten included adolescents. Four studies were conducted on elderly subjects and three included children, but none exclusively involved adolescents as the target population. The sample size was larger than 500 in 26 studies. Despite disagreement in terms of the degree of correlation, the studies generally showed that the anthropometric indicators of abdominal obesity were correlated with hypertension, diabetes, dyslipidemias, and coronary heart risk. The results of this review suggest that abdominal obesity is associated with metabolic diseases. However, there is a lack of studies involving the adolescent population, suggesting the need for further research in this area.

  18. A base de dados Scielo como fonte para pesquisas sobre o tema vacinação

    Directory of Open Access Journals (Sweden)

    Viviane Moreira Alves

    2006-01-01

    Full Text Available O objetivo desse estudo foi realizar um levantamento dos artigos publicados e disponíveis para a pesquisa na base de dados SCIELO sobre o tema vacinação. O estudo foi de caráter descritivo, baseado na consulta à base de dados SCIELO, onde buscamos os artigos que tinham associação com o tema escolhido. Foram encontrados 217 artigos e destes, após lidos, 87 foram selecionados. As categorias criadas foram: estudos experimentais, estudos bibliográficos e outros. As categorias “Estudos experimentais” e “Estudos bibliográficos” foram divididas em três subcategorias nomeadas de forma homônima em eficácia de vacinas, biotecnologia e prevenção. Concluímos que a pesquisa apontou temas de caráter bastante diversificado, com muitos trabalhos referentes a estudos experimentais.

  19. Ar-Ar_Redux: rigorous error propagation of 40Ar/39Ar data, including covariances

    Science.gov (United States)

    Vermeesch, P.

    2015-12-01

    Rigorous data reduction and error propagation algorithms are needed to realise Earthtime's objective to improve the interlaboratory accuracy of 40Ar/39Ar dating to better than 1% and thereby facilitate the comparison and combination of the K-Ar and U-Pb chronometers. Ar-Ar_Redux is a new data reduction protocol and software program for 40Ar/39Ar geochronology which takes into account two previously underappreciated aspects of the method: 1. 40Ar/39Ar measurements are compositional dataIn its simplest form, the 40Ar/39Ar age equation can be written as: t = log(1+J [40Ar/39Ar-298.5636Ar/39Ar])/λ = log(1 + JR)/λ Where λ is the 40K decay constant and J is the irradiation parameter. The age t does not depend on the absolute abundances of the three argon isotopes but only on their relative ratios. Thus, the 36Ar, 39Ar and 40Ar abundances can be normalised to unity and plotted on a ternary diagram or 'simplex'. Argon isotopic data are therefore subject to the peculiar mathematics of 'compositional data', sensu Aitchison (1986, The Statistical Analysis of Compositional Data, Chapman & Hall). 2. Correlated errors are pervasive throughout the 40Ar/39Ar methodCurrent data reduction protocols for 40Ar/39Ar geochronology propagate the age uncertainty as follows: σ2(t) = [J2 σ2(R) + R2 σ2(J)] / [λ2 (1 + R J)], which implies zero covariance between R and J. In reality, however, significant error correlations are found in every step of the 40Ar/39Ar data acquisition and processing, in both single and multi collector instruments, during blank, interference and decay corrections, age calculation etc. Ar-Ar_Redux revisits every aspect of the 40Ar/39Ar method by casting the raw mass spectrometer data into a contingency table of logratios, which automatically keeps track of all covariances in a compositional context. Application of the method to real data reveals strong correlations (r2 of up to 0.9) between age measurements within a single irradiation batch. Propertly taking

  20. genenames.org: the HGNC resources in 2011

    Science.gov (United States)

    Seal, Ruth L.; Gordon, Susan M.; Lush, Michael J.; Wright, Mathew W.; Bruford, Elspeth A.

    2011-01-01

    The HUGO Gene Nomenclature Committee (HGNC) aims to assign a unique gene symbol and name to every human gene. The HGNC database currently contains almost 30 000 approved gene symbols, over 19 000 of which represent protein-coding genes. The public website, www.genenames.org, displays all approved nomenclature within Symbol Reports that contain data curated by HGNC editors and links to related genomic, phenotypic and proteomic information. Here we describe improvements to our resources, including a new Quick Gene Search, a new List Search, an integrated HGNC BioMart and a new Statistics and Downloads facility. PMID:20929869

  1. Scientific journals in the SciELO database, indicators of impact and the relative position of Ambiente & Água

    Directory of Open Access Journals (Sweden)

    Nelson Wellausen Dias

    2010-12-01

    Full Text Available This editorial describes the process of periodic evaluation by CAPES, based on commercial indices proposed by companies such as the ISI FI by Thomson Reuters and SCImago by Scopus and public indices as proposed by SciELO and other freely calculated indices based on Google Scholar and investigates the impact position of the journal Ambiente & Agua compared with journals from the SciELO base. Results show that Ambiente & Agua is in the right path in the search for quality. Its editorial board strongly recommends that Brazilian public scientific agencies consider tools that are cost free and have large coverage for impact evaluation to allow the impact assessment of a range of emerging journals in a common and wide basis for all scientific journals.

  2. An overview of the Chemistry-Aerosol Mediterranean Experiment (ChArMEx)

    Science.gov (United States)

    Dulac, François

    2014-05-01

    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, http://charmex.lsce.ipsl.fr) is a French initiative of the MISTRALS meta-programme (Mediterranean Integrated Studies at Regional And Locals Scales, http://www.mistrals-home.org). It federates a great number of national and international cooperative research actions aiming at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The target is short-lived particulate and gaseous tropospheric trace species which are the cause of poor air quality events, have two-way interactions with climate, or impact the marine biogeochemistry, in a context of strong regional anthropogenic and climatic pressures. The six ChArMEx work packages include Emissions, Chemical processes and ageing, Transport processes and air quality, Aerosol-radiation-climate interactions, Deposition, and Present and future variability and trends. For several years, efforts have been deployed in several countries to develop (i) a network of relevant stations for atmospheric chemistry at background sites on islands and continental coasts around the basin and (ii) several intensive field campaigns including the operation of surface supersites and various instrumented mobile platforms (large and ultra-light aircraft, sounding and drifting balloons, ZeroCO2 sailboat). This presentation is an attempt to provide an overview of the various experimental, remote sensing and modelling efforts produced and to highlight major findings, by referencing more detailed ChArMEx presentations given in this conference and recently published or submitted papers. During the first phase of the project experimental efforts have been mainly concentrated on the western basin. Plans for the 2nd phase of ChArMEx, more dedicated towards the eastern basin, will also be given. In particular we plan to develop monitoring activities at

  3. Medicina y Seguridad del Trabajo, evaluación desde su ingreso en la Red SciELO (Scientific Electronic Library Online Medicina y Seguridad del Trabajo, evaluation since joining SciELO (Scientific Electronic Library Online

    Directory of Open Access Journals (Sweden)

    Ascensión Bernal Zamora

    2012-03-01

    Full Text Available Se realiza una revisión de los principales cambios editoriales y de contenido sufridos por la revista de Medicina y Seguridad del Trabajo durante los últimos 5 años, coincidiendo con el periodo desde que ingresó en SciELO (ScientificElectronic Library Online (2007-2011. En el periodo estudiado se han realizado un número de consultas a sus artículos superior a los 190 mil, ha tenido un Factor de Impacto (FI SciELO del 1.22, se ha incrementado el número de artículos recibidos de diferentes países de América y Europa y se la revista ha sido indizada en diferentes Bases de Datos bibliográficas internacionales (SciELO, Directory of Open Access Journals (DOAJ, Google Schoolar, Eprints in Library and InformationScience (E-LIS y LATINDEX y nacionales (IBECS, IME, Base de Datos del Consejo Superior de Investigaciones Científicas (CSIC, DIALNET y CUIDEN. La calidad editorial y de contenidos también se han visto mejoradas con diferentes modificaciones y cambios introducidos. Se cuenta con la participación editorial de la Organización Panamericana de la Salud, Oficina regional para las Américas de la Organización M undial del Salud (OPS/OMS, se ha producido un incremento superior al 40% de los artículos publicados en el último quinquenio respecto al periodo anterior, pasando de 118 a 202 artículos. El número de Editoriales y casos Clínicos también se incrementan en un porcentaje del 40 %. Los Artículos Originales se incrementan en algo más del 50% (53 versus 109, encontrando el mayor incremento en los Artículos de revisión que pasan de 3 en el primer anterior a 25 en el periodo de estudio. Por último, en 2011, Medicina y Seguridad en el Trabajo ha publicado por primera vez un número monográfico especial sobre Factores Psicosociales, Salud laboral y Salud Mental que incluye 15 artículos de revisión sobre temas de actualidad realizados por especialistas en la materia. Los resultados estimulan el afán por del Equipo Editorial

  4. Validation of satellite derived LHF using coare_3.0 scheme and time series data over north-east Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Muraleedharan, P.M.; Pankajakshan, T.; Sathe, P.V.

    to the scientific community as it call for near perfect observational platforms and sensors to Page 1 of 10Gayana (Concepción) - VALIDATION OF SATELLITE DERIVED LHF USING C... 8/11/2006http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717...>VALIDATION OF SATELLITE DERIVED LHF USING C... 8/11/2006http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-65382004000300019&lng=... Day and night passes of SSMI (wind speed and columnar water vapor) and TMI (sea surface temperature) data for the period July...

  5. Exploring the circumstellar disk-like structure of the B[e] supergiant LHA 120-S 73

    Czech Academy of Sciences Publication Activity Database

    Torres, A.F.; Cidale, L.S.; Kraus, Michaela; Arias, M.L.; Maravelias, Grigorios; Borges Fernandes, M.; Vallverdú, R.

    2016-01-01

    Roč. 58, č. 1 (2016), s. 120-122 E-ISSN 1669-9521 R&D Projects: GA MŠk(CZ) 7AMB14AR017; GA MŠk LG14013 Institutional support: RVO:67985815 Keywords : stars * early-type * circumstellar matter Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www.astronomiaargentina.org.ar/b58/2016baaa...58...120T.pdf

  6. A mini atlas of K-band spectra of southern symbiotic stars

    Czech Academy of Sciences Publication Activity Database

    Marchiano, P.E.; Cidale, L.S.; Arias, M.L.; Borges Fernandes, M.; Kraus, Michaela

    2015-01-01

    Roč. 57, č. 1 (2015), s. 87-89 E-ISSN 1669-9521 R&D Projects: GA ČR(CZ) GA14-21373S; GA MŠk(CZ) 7AMB14AR017 Institutional support: RVO:67985815 Keywords : binaries * symbiotic * stars Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b57/2015BAAA...57...87M.pdf

  7. www.meanders.org na internet com ecoturismo: uma interação comunicacional sustentável?

    OpenAIRE

    Laudo Kiyohiro Natsui

    2002-01-01

    A Teia de Alcance Mundial, como é conhecida a www da população que já tem acesso à internet, tem se tornado no Brasil rapidamente expressiva em tempos de mercados globais e, dentro deste contexto, a atividade do ecoturismo é analisada enquanto oferta e mensagem online. Realiza-se um estudo qualitativo exploratório no intuito de discutir a presente oferta ecoturística online e a mensagem propagada via rede. O termo ecoturismo é questionado, assim como as iniciativas que se apropriam da palavra...

  8. Newsbriefs www.iaea.org. January 2002

    International Nuclear Information System (INIS)

    2002-01-01

    In this newsbrief the topics covered include: categories of risk, nuclear materials, nuclear facilities, and radioactive sources; a special session of IAEA experts meeting on the subject; financing the prevention of terrorism; nuclear security discussed by the IAEA Board of Governors; technical cooperation for security; use of electron beam scanning for mail safety; sustainable development; radioactive waste management; health programs in Latin America; landmine cleanup; clean water programmes

  9. The treatable intellectual disability APP www.treatable-id.org: A digital tool to enhance diagnosis & care for rare diseases

    Directory of Open Access Journals (Sweden)

    van Karnebeek Clara D M

    2012-07-01

    Full Text Available Abstract Background Intellectual disability (ID is a devastating and frequent condition, affecting 2-3% of the population worldwide. Early recognition of treatable underlying conditions drastically improves health outcomes and decreases burdens to patients, families and society. Our systematic literature review identified 81 such inborn errors of metabolism, which present with ID as a prominent feature and are amenable to causal therapy. The WebAPP translates this knowledge of rare diseases into a diagnostic tool and information portal. Methods & results Freely available as a WebAPP via http://www.treatable-id.org and end 2012 via the APP store, this diagnostic tool is designed for all specialists evaluating children with global delay / ID and laboratory scientists. Information on the 81 diseases is presented in different ways with search functions: 15 biochemical categories, neurologic and non-neurologic signs & symptoms, diagnostic investigations (metabolic screening tests in blood and urine identify 65% of all IEM, therapies & effects on primary (IQ/developmental quotient and secondary outcomes, and available evidence For each rare condition a ‘disease page’ serves as an information portal with online access to specific genetics, biochemistry, phenotype, diagnostic tests and therapeutic options. As new knowledge and evidence is gained from expert input and PubMed searches this tool will be continually updated. The WebAPP is an integral part of a protocol prioritizing treatability in the work-up of every child with global delay / ID. A 3-year funded study will enable an evaluation of its effectiveness. Conclusions For rare diseases, a field for which financial and scientific resources are particularly scarce, knowledge translation challenges are abundant. With this WebAPP technology is capitalized to raise awareness for rare treatable diseases and their common presenting clinical feature of ID, with the potential to improve health outcomes

  10. The treatable intellectual disability APP www.treatable-id.org: A digital tool to enhance diagnosis & care for rare diseases

    Science.gov (United States)

    2012-01-01

    Background Intellectual disability (ID) is a devastating and frequent condition, affecting 2-3% of the population worldwide. Early recognition of treatable underlying conditions drastically improves health outcomes and decreases burdens to patients, families and society. Our systematic literature review identified 81 such inborn errors of metabolism, which present with ID as a prominent feature and are amenable to causal therapy. The WebAPP translates this knowledge of rare diseases into a diagnostic tool and information portal. Methods & results Freely available as a WebAPP via http://www.treatable-id.org and end 2012 via the APP store, this diagnostic tool is designed for all specialists evaluating children with global delay / ID and laboratory scientists. Information on the 81 diseases is presented in different ways with search functions: 15 biochemical categories, neurologic and non-neurologic signs & symptoms, diagnostic investigations (metabolic screening tests in blood and urine identify 65% of all IEM), therapies & effects on primary (IQ/developmental quotient) and secondary outcomes, and available evidence For each rare condition a ‘disease page’ serves as an information portal with online access to specific genetics, biochemistry, phenotype, diagnostic tests and therapeutic options. As new knowledge and evidence is gained from expert input and PubMed searches this tool will be continually updated. The WebAPP is an integral part of a protocol prioritizing treatability in the work-up of every child with global delay / ID. A 3-year funded study will enable an evaluation of its effectiveness. Conclusions For rare diseases, a field for which financial and scientific resources are particularly scarce, knowledge translation challenges are abundant. With this WebAPP technology is capitalized to raise awareness for rare treatable diseases and their common presenting clinical feature of ID, with the potential to improve health outcomes. This innovative digital

  11. SciELO, Scientific Electronic Library Online, a Database of Open Access Journals

    Directory of Open Access Journals (Sweden)

    Rogerio Meneghini

    2013-09-01

    Full Text Available   This essay discusses SciELO, a scientific journal database operating in 14 countries. It covers over 1000 journals providing open access to full text and table sets of scientometrics data. In Brazil it is responsible for a collection of nearly 300 journals, selected along 15 years as the best Brazilian periodicals in natural and social sciences. Nonetheless, they still are national journal in the sense that over 80% of the articles are published by Brazilian scientists. Important initiatives focused on professionalization and internationalization are considered to bring these journals to a higher level of quality and visibility. DOI: 10.18870/hlrc.v3i3.153

  12. www.ajol.info www.bioline.org.br/ja The Abundance and ...

    African Journals Online (AJOL)

    ADOWIE PERE

    indication that the area is an important ecological zone for benthos macroinvertebrates conservation. ... Heck and Coen, (1995), the estuarine and mangroves ..... ecological services. Callinectes amnicola was the most abundant and are economically important species locally; hence the need to integrate a sustainable ...

  13. Primar orgânica: inovação em tempos de crise

    Directory of Open Access Journals (Sweden)

    Mariana Baldi

    Full Text Available Este artigo resulta de um estudo de caso na Primar Orgânica, empresa de aqüicultura do Rio Grande do Norte, tendo como foco o processo de transformação de carcinicultura convencional para a orgânica, pelo qual passou a empresa. Única na produção de camarão orgânico naquele estado, a Primar Orgânica é a primeira empresa do mundo na criação de ostras orgânicas. Como arcabouço teórico utilizou-se a resource-based view (RBV (BARNEY, 1991, 2001; KATILA; SHANE, 2005; WERNERFELT, 1984, a teoria institucional (TI e as redes sociais. A TI amplia o conceito de ambiente utilizado pela RBV, ao agregar o conceito de ambiente institucional, enquanto a teoria de redes centra no inter-relacionamento entre os atores e na estrutura da rede como inibidores ou potencializadores da capacidade de inovar (LIU, MADHAVAN, SUDHARSHAN, 2005. O pressuposto central é de que inovação seja um processo imerso no contexto social (LUNDVALL, 1993. A análise dos dados, obtidos através de entrevistas em profundidade e de documentos, denota como a escassez de recursos e a imersão do empreendedor em contextos diferentes possibilitou uma inovação tecnológica e gerencial, levando a organização a alcançar vantagem competitiva baseada numa estratégia centrada em recursos diferenciados.

  14. Next-to-leading order electroweak corrections to off-shell WWW production at the LHC arXiv

    CERN Document Server

    Schönherr, Marek

    Triboson processes allow for a measurement of the triple and quartic couplings of the Standard Model gauge bosons, which can be used to constrain anomalous gauge couplings. In this paper we calculate the next-to-leading order electroweak corrections to fully off-shell $W^-W^+W^+$ production, namely the production of a $\\ell_1^-\\ell_2^+\\ell_3^+\\bar{\

  15. Unraveling the nature of B[e] star candidates

    Czech Academy of Sciences Publication Activity Database

    Arias, M.L.; Torres, A.F.; Cidale, L.S.; Kraus, Michaela

    2013-01-01

    Roč. 56, č. 1 (2013), s. 171-174 E-ISSN 1669-9521 Institutional support: RVO:67985815 Keywords : Be star * massive star * spectroscopic observations Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b56/2013baaa...56...171A.pdf

  16. Macrófitas aquáticas em tratamento de águas contaminadas por arsênio

    OpenAIRE

    Santos, Edilayne Cristina

    2008-01-01

    A poluição das águas por arsênio, e compostos: orgânicos, fosfatados e nitrogenados é um dos maiores problemas do mundo moderno. A fitorremediação tem sido utilizada, na busca de espécies vegetais com potencial para a remoção desses compostos. Nesse intuito, espécies de macrófitas foram colocadas em presença de arsênio em meio aquoso nutritivo, a fim de estudar a absorção do arsênio pelas mesmas e a sua cinética. A análise do crescimento e da produção de biomassa, em curto intervalo de tempo,...

  17. sORFs.org: a repository of small ORFs identified by ribosome profiling.

    Science.gov (United States)

    Olexiouk, Volodimir; Crappé, Jeroen; Verbruggen, Steven; Verhegen, Kenneth; Martens, Lennart; Menschaert, Gerben

    2016-01-04

    With the advent of ribosome profiling, a next generation sequencing technique providing a "snap-shot'' of translated mRNA in a cell, many short open reading frames (sORFs) with ribosomal activity were identified. Follow-up studies revealed the existence of functional peptides, so-called micropeptides, translated from these 'sORFs', indicating a new class of bio-active peptides. Over the last few years, several micropeptides exhibiting important cellular functions were discovered. However, ribosome occupancy does not necessarily imply an actual function of the translated peptide, leading to the development of various tools assessing the coding potential of sORFs. Here, we introduce sORFs.org (http://www.sorfs.org), a novel database for sORFs identified using ribosome profiling. Starting from ribosome profiling, sORFs.org identifies sORFs, incorporates state-of-the-art tools and metrics and stores results in a public database. Two query interfaces are provided, a default one enabling quick lookup of sORFs and a BioMart interface providing advanced query and export possibilities. At present, sORFs.org harbors 263 354 sORFs that demonstrate ribosome occupancy, originating from three different cell lines: HCT116 (human), E14_mESC (mouse) and S2 (fruit fly). sORFs.org aims to provide an extensive sORFs database accessible to researchers with limited bioinformatics knowledge, thus enabling easy integration into personal projects. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  18. The syntheses of radiolabelled Org 5222 and its main metabolite Org 30526

    International Nuclear Information System (INIS)

    Vader, Jan; Kaspersen, Frans; Sperling, Eric; Schlachter, Irene; Terpstra, Annie; Hilberink, Peter; Wagenaars, Gerard

    1994-01-01

    The syntheses of trans-5-chloro-2,3,3a-12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7] oxepino[4 ,5-c]pyrrole (Org 5222), a potential antipsychotic compound, labelled with 3 H, 14 C and 36 Cl and trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]-oxepino[4, 5-c] pyrrole (Org 30526) labelled with 3 H are described. 3 H-labelled Org 5222 of low specific activity was prepared by a base catalyzed exchange with tritiated water of an amide precursor, 3 H-labelled Org 5222 with a high specific activity by a catalytic reductive dehalogenation. 3 H-labelled Org 30526 was prepared both by demethylation of 3 H-Org 5222 and by catalytic reductive iodination of 11-iodo-Org 30526. 14 C-labelled Org 5222 was synthesized in 6 steps using 14 C-sarcosine as starting material. 36 Cl-labelled Org 5222 was prepared by diazotation reaction in the presence of H 36 Cl. (author)

  19. Small angle Ar2+ + Ar collisions

    International Nuclear Information System (INIS)

    Stevens, J.J.

    1983-01-01

    Electron capture in Ar 2+ + Ar is studied at low keV energies. Using Ar 2+ + He collisions as a calibration, it is shown that the dominant single electron capture process is endothermic and of the type Ar 2+ ( 3 P) + ArAr + ( 2 P) + Ar + (3s 2 3p 4 nI), with nI primarily being 3d and 4p. Weaker exothermic processes are also found and are due mainly to the existence of long-lived highly-excited states in the incident Ar 2+ beam. The direct scattering and double electron capture processes are also studied. Direct scattering occurs with no target excitation. Differential cross sections are presented for the collision processes. The single electron capture results are interpreted using a simple model in which a strongly attractive intermediate state couples with incident and outgoing channels

  20. The AR Sandbox: Augmented Reality in Geoscience Education

    Science.gov (United States)

    Kreylos, O.; Kellogg, L. H.; Reed, S.; Hsi, S.; Yikilmaz, M. B.; Schladow, G.; Segale, H.; Chan, L.

    2016-12-01

    The AR Sandbox is a combination of a physical box full of sand, a 3D (depth) camera such as a Microsoft Kinect, a data projector, and a computer running open-source software, creating a responsive and interactive system to teach geoscience concepts in formal or informal contexts. As one or more users shape the sand surface to create planes, hills, or valleys, the 3D camera scans the surface in real-time, the software creates a dynamic topographic map including elevation color maps and contour lines, and the projector projects that map back onto the sand surface such that real and projected features match exactly. In addition, users can add virtual water to the sandbox, which realistically flows over the real surface driven by a real-time fluid flow simulation. The AR Sandbox can teach basic geographic and hydrologic skills and concepts such as reading topographic maps, interpreting contour lines, formation of watersheds, flooding, or surface wave propagation in a hands-on and explorative manner. AR Sandbox installations in more than 150 institutions have shown high audience engagement and long dwell times of often 20 minutes and more. In a more formal context, the AR Sandbox can be used in field trip preparation, and can teach advanced geoscience skills such as extrapolating 3D sub-surface shapes from surface expression, via advanced software features such as the ability to load digital models of real landscapes and guiding users towards recreating them in the sandbox. Blueprints, installation instructions, and the open-source AR Sandbox software package are available at http://arsandbox.org .

  1. Identification of excess 40Ar by the 40Ar/39Ar age spectrum technique

    International Nuclear Information System (INIS)

    Lanphere, M.A.; Dalrymple, G.B.

    1976-01-01

    40 Ar/ 39 Ar incremental heating experiments on igneous plagioclase, biotite, and pyroxene that contain known amounts of excess 40 Ar indicate that saddle-shaped age spectra are diagnostic of excess 40 Ar in igneous minerals as well as in igneous rocks. The minima in the age spectra approach but do not reach the crystallization age. Neither the age spectrum diagram nor the 40 Ar/ 36 Ar versus 39 Ar/ 36 Ar isochron diagram reliably reveal the crystallization age in such samples. (Auth.)

  2. The ChArMEx database

    Science.gov (United States)

    Ferré, Hélène; Belmahfoud, Nizar; Boichard, Jean-Luc; Brissebrat, Guillaume; Cloché, Sophie; Descloitres, Jacques; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Mière, Arnaud; Ramage, Karim; Vermeulen, Anne; Boulanger, Damien

    2015-04-01

    have been inserted in a relational database, in order to enable more accurate selection and download of different datasets in a shared format. Many dedicated satellite products (SEVIRI, TRIMM, PARASOL...) are processed and will soon be accessible through the database website. In order to meet the operational needs of the airborne and ground based observational teams during the ChArMEx campaigns, a day-to-day chart display website has been developed and operated: http://choc.sedoo.org. It offers a convenient way to browse weather conditions and chemical composition during the campaign periods. Every scientist is invited to visit the ChArMEx websites, to register and to request data. Feel free to contact charmex-database@sedoo.fr for any question.

  3. Aprovechamiento de residuos sólidos en un sistema hidro-orgánico de agricultura urbana

    Directory of Open Access Journals (Sweden)

    Ortiz Tovar Diego Fernando

    2008-12-01

    Full Text Available AR-SA";;">La investigación tuvo por objeto diseñar un sistema hidroorgánico de producción de hortalizas en áreas pequeñas, con el fin de contribuir a la seguridad alimentaria de la población urbana y al aprovechamiento de los residuos sólidos de la ciudad de Popayán. Se diseñó un sistema a partir de material reciclado y se evaluó utilizando tres tratamientos como fuente nutricional (Lixiviado orgánico, Lixiviado orgánico suplementado, solución nutritiva común y como indicador biológico cilantro (Coriandrum sativum l.. La respuesta de las plantas fue evaluada por crecimiento y desarrollo. El sistema para producción urbana de hortalizas permitió obtener producciones hasta de 627 g m-2, superando la producción en agricultura tradicional (227 g. La mejor fuente nutricional fue la solución nutritiva comercial.

  4. Spectroanalytical investigations on inductively coupled N2/Ar and Ar/Ar high frequency plasmas

    International Nuclear Information System (INIS)

    Malinowski, P.; Mazurkiewicz, M.; Nickel, H.

    1981-03-01

    In order to improve the detection limits of trace elements in corrosion products of metallic materials, the inductively coupled plasma excitation source (ICP) was applied for spectroscopic analysis. Besides optimizing the working conditions for the mentioned materials, the fundamental research clearing the excitation processes in ICP was carried out. Basicly, two plasma systems were investigated: the nitrogen cooled N 2 /Ar- and pure Ar/Ar-plasma. The computed detection limits for 8 chosen elements are between 0.1 and 50 μg ml -1 in both plasmas. The advantage of ion lines was clearly present; in N 2 /Ar-plasma it was larger than in Ar/Ar-plasma. The excitation temperatures measured with help of ArI, FeI and ZnI lines rise with increasing power and decreasing distance from the induction coil. The distribution of Zn excitation temperature in N 2 /Ar-plasma as well as the measured N + 2 rotational and CN vibrational temperatures indicate, that the toroidal structure of Ar/Ar-plasma is not analogue to the N 2 /Ar-plasma. The values of the various excitation temperatures (Ar, Fe, Zn) and the differences between the excitation, vibration, rotation and ionization temperatures (Tsub(i) > Tsub(n) = Tsub(vib) > Tsub(rot)) indicate an absence of thermal equilibrium in the concerned system. (orig.)

  5. Genenames.org: the HGNC and VGNC resources in 2017.

    Science.gov (United States)

    Yates, Bethan; Braschi, Bryony; Gray, Kristian A; Seal, Ruth L; Tweedie, Susan; Bruford, Elspeth A

    2017-01-04

    The HUGO Gene Nomenclature Committee (HGNC) based at the European Bioinformatics Institute (EMBL-EBI) assigns unique symbols and names to human genes. Currently the HGNC database contains almost 40 000 approved gene symbols, over 19 000 of which represent protein-coding genes. In addition to naming genomic loci we manually curate genes into family sets based on shared characteristics such as homology, function or phenotype. We have recently updated our gene family resources and introduced new improved visualizations which can be seen alongside our gene symbol reports on our primary website http://www.genenames.org In 2016 we expanded our remit and formed the Vertebrate Gene Nomenclature Committee (VGNC) which is responsible for assigning names to vertebrate species lacking a dedicated nomenclature group. Using the chimpanzee genome as a pilot project we have approved symbols and names for over 14 500 protein-coding genes in chimpanzee, and have developed a new website http://vertebrate.genenames.org to distribute these data. Here, we review our online data and resources, focusing particularly on the improvements and new developments made during the last two years. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  6. Kinetics of Ar isotopes during neutron irradiation: 39Ar loss from minerals as a source of error in 40Ar/39Ar dating

    International Nuclear Information System (INIS)

    Hess, J.C.; Lippolt, H.J.

    1986-01-01

    The loss of 39 Ar from minerals in the course of neutron activation for 40 Ar/ 39 Ar dating is studied by directly measuring the loss rates in vacuum-sealed ampoules. Biotite shows 39 Ar losses between 0.1% and 16%. These losses are predominantly due to diffusion processes from K-poor alteration-phase intergrowths in the biotites at the elevated temperatures during the irradiation. Estimates for the irradiation temperatures range from 150 0 to 180 0 C. Direct 39 Ar recoil loss from biotite seems to be minor compared to difussion loss of recoil-implanted 39 Ar. Precise 40 Ar/ 39 Ar dating of biotites therefore requires the measurement of the 39 Ar losses during irradiation. Glauconite loses not only neutron-induced Ar isotopes ( 39 Ar: 20-22%, 37 Ar: 17-19%) but also radiogenic 40 Ar(∼9%). Slight 39 Ar losses are also observed for light micas (0.2% and 0.35%), hornblendes (0.1%) and sanidines (200 and 700 ppm). 25 refs.; 4 figs.; 6 tabs

  7. DLSanalysis.org: a web interface for analysis of dynamic light scattering data.

    Science.gov (United States)

    Hansen, Steen

    2018-03-01

    A web interface ( www.DLSanalysis.org ) for indirect Laplace transformation of dynamic light scattering data is presented. When experimental data are uploaded to the server they are processed in a few seconds, and the result is displayed on the screen in the form of a size distribution together with the experimental data and the fit to the data. No other user input than the experimental data is necessary, but various options for the analysis may be selected. No local installation of software or registration is necessary. The result of the analysis can be downloaded.

  8. Prostate Cell Specific Regulation of Androgen Receptor Phosphorylation in Vivo

    Science.gov (United States)

    2009-11-01

    average counts per minute ( CPM ). Columns, mean (*, P = 0.006); error bars, SE. ART-27 Inhibits AR Target Genes www.aacrjournals.org 3145 Cancer Res 2009; 69...publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked advertisement in accordance with

  9. Influences of atom Ar on Ar at C60 + Ar at C60 collisions

    International Nuclear Information System (INIS)

    Zhao Qiang; Zhou Hongyu; Zhang Fengshou

    2007-01-01

    A semi-emperical molecular dynamics model was developed. The central collisions of C 60 + C 60 and Ar at C 60 + Ar at C 60 at the same incident energy were investigated within this model. The fullerene dimers could be formed by a self-assembly of C 60 fullerene, and the new fullerene structure like 'peanut' could be formed by a self-assembly of Ar at C 60 . It was found that atom Ar had a great effect on the collision of Ar at C 60 + Ar at C 60 . (authors)

  10. Estado evolutivo de estrellas con fen ́omeno B[e

    Czech Academy of Sciences Publication Activity Database

    Aidelman, Y.J.; Cidale, L.S.; Borges Fernandes, M.; Kraus, Michaela

    2012-01-01

    Roč. 55, č. 1 (2012), s. 39-42 E-ISSN 1669-9521. [Asociación Argentina de Astronomía : Reunion Anual. Mar del Plata, 17.09.2012-21.09.2012] R&D Projects: GA ČR(CZ) GAP209/11/1198; GA MŠk 7AMB12AR021 Institutional support: RVO:67985815 Keywords : emission-line stars * early-type stars * fundamental parameters Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b55/boletin_55.pdf

  11. Spectroscopic study of the B[e] supergiant LHA 120-S 35

    Czech Academy of Sciences Publication Activity Database

    Torres, A.F.; Oksala, Mary E.; Cidale, L.S.; Kraus, Michaela; Borges Fernandes, M.; Barba, R.

    2012-01-01

    Roč. 55, č. 1 (2012), s. 155-158 E-ISSN 1669-9521. [Asociación Argentina de Astronomía : Reunion Anual. Mar del Plata, 17.09.2012-21.09.2012] R&D Projects: GA ČR(CZ) GAP209/11/1198; GA MŠk 7AMB12AR021 Institutional support: RVO:67985815 Keywords : LHA 120-S 35 * spectroscopic description Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b55/boletin_55.pdf

  12. Near-infrared spectroscopic survey of galactic B[e] stars

    Czech Academy of Sciences Publication Activity Database

    Muratore, M.F.; Kraus, Michaela; de Wit, W.J.

    2012-01-01

    Roč. 55, č. 1 (2012), s. 123-126 E-ISSN 1669-9521. [Asociación Argentina de Astronomía : Reunion Anual. Mar del Plata, 17.09.2012-21.09.2012] R&D Projects: GA ČR(CZ) GAP209/11/1198; GA MŠk 7AMB12AR021 Institutional support: RVO:67985815 Keywords : circumstellar * CO emission * spectrograph VLT/CRIRES Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b55/boletin_55.pdf

  13. PRELIMINARY INVESTIGATIONS OF THE CLINICAL-PHARMACOLOGY OF 3 SHORT-ACTING NONDEPOLARIZING NEUROMUSCULAR BLOCKING-AGENTS, ORG 9453, ORG 9489 AND ORG 9487

    NARCIS (Netherlands)

    WIERDA, JMKH; BEAUFORT, AM; KLEEF, UW; SMEULERS, NJ; AGOSTON, S

    Three muscle relaxants, Org 9453, Org 9489 and Org 9487, short-acting in animals, were investigated to establish their profiles in humans. Potency, time course of action, and pharmacokinetic behaviour were studied in 90 healthy patients during fentanyl/halothane/N2O anaesthesia. Neuromuscular

  14. Spent fuel composition database system on WWW. SFCOMPO on WWW Ver.2

    International Nuclear Information System (INIS)

    Mochizuki, Hiroki; Suyama, Kenya; Nomura, Yasushi; Okuno, Hiroshi

    2001-08-01

    'SFCOMPO on WWW Ver.2' is an advanced version of 'SFCOMPO on WWW (Spent Fuel Composition Database System on WWW' released in 1997. This new version has a function of database management by an introduced relational database software 'PostgreSQL' and has various searching methods. All of the data required for the calculation of isotopic composition is available from the web site of this system. This report describes the outline of this system and the searching method using Internet. In addition, the isotopic composition data and the reactor data of the 14 LWRs (7 PWR and 7 BWR) registered in this system are described. (author)

  15. Acumulación de arsénico en el cultivo de habas (Vicia Faba

    Directory of Open Access Journals (Sweden)

    Francisco Prieto García

    2007-01-01

    Full Text Available La presencia de arsénico en aguas y suelos de Zimapán, en el estado de Hidalgo, México, causa que los cultivos de haba presenten concentraciones apreciables de dicho elemento. Los suelos evaluados presentaron texturas, conductividad, contenidos de N y de arsénico diferentes, pero resultados similares en pH, potencial redox, y contenido de materia orgánica. La elevada bioacumulación de arsénico en estos suelos fue directamente proporcional al tiempo de exposición. Las concentraciones de arsénico acumuladas más altas se obtuvieron en la raíz, el tallo, y las hojas, respectivamente. Concentraciones de 4 mg l-1, fueron letales para el cultivo; el fenómeno se apreció a partir de la etapa III de desarrollo, con la aparición de daños en las raíces y un fuerte efecto en la floración, que inhibió la formación de vainas.

  16. Fault Tolerant Paradigms

    Science.gov (United States)

    2016-02-26

    ln d ) -time in that case.14 We prove Theorem 7 by following the generic compressive phase retrieval recipe presented in [24]. Let C ∈ Cm×d be any...retrieval, available online: arXiv:1312.0158. [20] S. Cook , The P versus NP problem, available online: http://www.claymath.org/millennium/PvsNP

  17. What do we know about mass ejection in B Supergiant Stars?

    Czech Academy of Sciences Publication Activity Database

    Haucke, M.; Tomić, S.; Cidale, L.S.; Kraus, Michaela; Aret, A.

    2016-01-01

    Roč. 58, č. 1 (2016), s. 171-173 E-ISSN 1669-9521 R&D Projects: GA ČR(CZ) GA14-21373S Institutional support: RVO:67985815 Keywords : stars * early-type * supergian Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b58/2016baaa...58...171H.pdf

  18. Probing the structure and dynamics of B[e] supergiant stars' disks

    Czech Academy of Sciences Publication Activity Database

    Kraus, Michaela

    2016-01-01

    Roč. 58, č. 1 (2016), s. 70-76 E-ISSN 1669-9521 R&D Projects: GA ČR(CZ) GA14-21373S Institutional support: RVO:67985815 Keywords : circumstellar matter * infrared * stars Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b58/2016baaa...58...70K.pdf

  19. The ChArMEx database

    Science.gov (United States)

    Ferré, Hélène; Descloitres, Jacques; Fleury, Laurence; Boichard, Jean-Luc; Brissebrat, Guillaume; Focsa, Loredana; Henriot, Nicolas; Mastrorillo, Laurence; Mière, Arnaud; Vermeulen, Anne

    2013-04-01

    (SEVIRI, TRIMM, PARASOL...) stored in the ICARE data archive using OpeNDAP protocole The website will soon propose new facilities. In particular, many in situ datasets will be homogenized and inserted in a relational database, in order to enable more accurate data selection and download of different datasets in a shared format. In order to meet the operational needs of the airborne and ground based observational teams during the ChArMEx 2012 pre-campaign and the 2013 experiment, a day-to-day quick look and report display website has been developed too: http://choc.sedoo.org. It offers a convenient way to browse weather conditions and chemical composition during the campaign periods.

  20. Spent fuel composition database system on WWW. SFCOMPO on WWW Ver.2

    Energy Technology Data Exchange (ETDEWEB)

    Mochizuki, Hiroki [Japan Research Institute, Ltd., Tokyo (Japan); Suyama, Kenya; Nomura, Yasushi; Okuno, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-08-01

    'SFCOMPO on WWW Ver.2' is an advanced version of 'SFCOMPO on WWW' ('Spent Fuel Composition Database System on WWW') released in 1997. This new version has a function of database management by an introduced relational database software 'PostgreSQL' and has various searching methods. All of the data required for the calculation of isotopic composition is available from the web site of this system. This report describes the outline of this system and the searching method using Internet. In addition, the isotopic composition data and the reactor data of the 14 LWRs (7 PWR and 7 BWR) registered in this system are described. (author)

  1. QUANTIFICAÇÃO DO USO DA CRIOTERAPIA NO DESEMPENHO FÍSICO E TRATAMENTO DE LESÕES NA BASE DE DADOS SCIELO.ORG

    Directory of Open Access Journals (Sweden)

    Thiago Siqueira dos Santos

    2014-02-01

    Full Text Available Introduction: Defined as a therapeutic procedure for application of local cold. The cryotherapy is used both for the treatment of lesions causing local analgesia, reducing edema, reducing inflammation; and for improving physical performance as a method to enhance recovery post workouts. Objective: The objective of this literature review was to determine how many articles have studied the use of cryotherapy for improved physical performance and and how to treatment of injuries, as well as analyzing the methods of application of cryotherapy, objectives and results. Materials and Methods: Was used as database virtual library SciELO.org, with the search word "cryotherapy", the results were analyzed in this way the work chosen should meet the criteria. Results: The selected articles were characterized and organized into two frames as: author, sample, cryotherapy (application method; goal and results. Discussion: This study showed that there are five studies that investigated the use of cryotherapy for improved physical performance and eight studies that investigated the use of cryotherapy for the treatment of muscle injuries, joint or bone. Conclusion: Few studies found that examined the effects on improvement in physical performance and injury treatment, cryotherapy was shown as a way beneficial to analgesic, and decrease pain in the treatment of injuries, the studies that assessed for improvement in physical performance demonstrated that there is an efficient way to obtain the expected results.

  2. Simultaneous measurement of the 37Ar and 39Ar activity

    International Nuclear Information System (INIS)

    Fisenko, A.V.

    1978-01-01

    A method for simultaneous measurement of 37 Ar and 39 Ar activities, based on the different radiation penetrabilities of these isotopes is described. Two versions are realized. In the first case, a two-section detector is used whose partition partially transmits 39 Ar β-radiation and fully absorbs 37 Ar Auger electrons. A mixture of 37 Ar and 39 Ar is introduced into an internal counter operating at anticoincidences with an external counter. In the second version, a scintillation detector is used as an external counter, while the 37 Ar- 39 Ar mixture is introduced into a gas counter with a thin cathode. The rated detection efficiency of 37 Ar radiation in both versions is 80%. When measurement duration is 500 h, the sensitivity is approximately 10 -14 and 6x10 -15 Ci for 39 Ar and 37 Ar respectively

  3. Determination of Ar metastable atom densities in Ar and Ar/H2 inductively coupled low-temperature plasmas

    International Nuclear Information System (INIS)

    Fox-Lyon, N; Knoll, A J; Oehrlein, G S; Franek, J; Demidov, V; Koepke, M; Godyak, V

    2013-01-01

    Ar metastable atoms are important energy carriers and surface interacting species in low-temperature plasmas that are difficult to quantify. Ar metastable atom densities (N Ar,m ) in inductively coupled Ar and Ar/H 2 plasmas were obtained using a model combining electrical probe measurements of electron density (N e ) and temperature (T e ), with analysis of spectrally resolved Ar plasma optical emission based on 3p → 1s optical emission ratios of the 419.8 nm line to the 420.1 nm line. We present the variation of N Ar,m as the Ar pressure and the addition of H 2 to Ar are changed comparatively to recent adsorption spectroscopy measurements. (paper)

  4. The enigmatic wind of 55 Cygni

    Czech Academy of Sciences Publication Activity Database

    Haucke, M.; Kraus, Michaela; Venero, R.O.J.; Cidale, L.S.; Nickeler, Dieter Horst; Tomić, S.; Curé, M.

    2013-01-01

    Roč. 56, č. 1 (2013), s. 191-194 E-ISSN 1669-9521 R&D Projects: GA ČR(CZ) GAP209/11/1198 Institutional support: RVO:67985815 Keywords : line profiles * stellar wind * spectroscopic observin Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www. astronomia argentina.org.ar/b56/2013baaa...56...191H.pdf

  5. An update on sORFs.org: a repository of small ORFs identified by ribosome profiling.

    Science.gov (United States)

    Olexiouk, Volodimir; Van Criekinge, Wim; Menschaert, Gerben

    2018-01-04

    sORFs.org (http://www.sorfs.org) is a public repository of small open reading frames (sORFs) identified by ribosome profiling (RIBO-seq). This update elaborates on the major improvements implemented since its initial release. sORFs.org now additionally supports three more species (zebrafish, rat and Caenorhabditis elegans) and currently includes 78 RIBO-seq datasets, a vast increase compared to the three that were processed in the initial release. Therefore, a novel pipeline was constructed that also enables sORF detection in RIBO-seq datasets comprising solely elongating RIBO-seq data while previously, matching initiating RIBO-seq data was necessary to delineate the sORFs. Furthermore, a novel noise filtering algorithm was designed, able to distinguish sORFs with true ribosomal activity from simulated noise, consequently reducing the false positive identification rate. The inclusion of other species also led to the development of an inner BLAST pipeline, assessing sequence similarity between sORFs in the repository. Building on the proof of concept model in the initial release of sORFs.org, a full PRIDE-ReSpin pipeline was now released, reprocessing publicly available MS-based proteomics PRIDE datasets, reporting on true translation events. Next to reporting those identified peptides, sORFs.org allows visual inspection of the annotated spectra within the Lorikeet MS/MS viewer, thus enabling detailed manual inspection and interpretation. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  6. All rights reserved www.ajol.infoand www.bioline.org.br/ja Impact of ...

    African Journals Online (AJOL)

    ADOWIE PERE

    electricity has become a common practice all over the world (Langfort, 1990; Kaushal et al. .... electric power in the generator. The steam generated ..... little solar energy, it is assumed that its influence ..... Biometry: the principles and practice of ...

  7. www.ajol.info and www.bioline.org.br/ja Evaluation of Serum Anion ...

    African Journals Online (AJOL)

    ADOWIE PERE

    pregnant control, and 20 pregnant women in each of the three trimesters of pregnancy. Ethical approval was ... regulate nutrient balance during this period is critical to the health of the ... atoms fall back to the ground state, light of characteristic ...

  8. All rights reserved www.ajol.info and www.bioline.org.br/ja Drought ...

    African Journals Online (AJOL)

    ADOWIE PERE

    vegetation growth and time lag in their response to dry or wet condition. © JASEM ... enhancing losses of life, human suffering and causing damage to the ... The southern part receives .... weather condition over most of the Sahelian stations.

  9. All rights reserved www.ajol.info and www.bioline.org.br/ja Drought ...

    African Journals Online (AJOL)

    ADOWIE PERE

    century as the result show a rapid decline in its occurrence which indicates improvement in rainfall. On the other ... caused a sudden break of early rainfall, poor spatio- temporal ..... Characteristics of 20th ... and Applied Genetics, 125, 625-645.

  10. 40Ar/39Ar geochronology of terrestrial pyroxene

    Science.gov (United States)

    Ware, Bryant; Jourdan, Fred

    2018-06-01

    Geochronological techniques such as U/Pb in zircon and baddeleyite and 40Ar/39Ar on a vast range of minerals, including sanidine, plagioclase, and biotite, provide means to date an array of different geologic processes. Many of these minerals, however, are not always present in a given rock, or can be altered by secondary processes (e.g. plagioclase in mafic rocks) limiting our ability to derive an isotopic age. Pyroxene is a primary rock forming mineral for both mafic and ultramafic rocks and is resistant to alteration process but attempts to date this phase with 40Ar/39Ar has been met with little success so far. In this study, we analyzed pyroxene crystals from two different Large Igneous Provinces using a multi-collector noble gas mass spectrometer (ARGUS VI) since those machines have been shown to significantly improve analytical precision compared to the previous single-collector instruments. We obtain geologically meaningful and relatively precise 40Ar/39Ar plateau ages ranging from 184.6 ± 3.9 to 182.4 ± 0.8 Ma (2σ uncertainties of ±1.8-0.4%) and 506.3 ± 3.4 Ma for Tasmanian and Kalkarindji dolerites, respectively. Those data are indistinguishable from new and/or published U-Pb and 40Ar/39Ar plagioclase ages showing that 40Ar/39Ar dating of pyroxene is a suitable geochronological tool. Scrutinizing the analytical results of the pyroxene analyses as well as comparing them to the analytical result from plagioclase of the same samples indicate pure pyroxene was dated. Numerical models of argon diffusion in plagioclase and pyroxene support these observations. However, we found that the viability of 40Ar/39Ar dating approach of pyroxene can be affected by irradiation-induced recoil redistribution between thin pyroxene exsolution lamellae and the main pyroxene crystal, hence requiring careful petrographic observations before analysis. Finally, diffusion modeling show that 40Ar/39Ar of pyroxene can be used as a powerful tool to date the formation age of mafic

  11. Regional and global science: Publications from Latin America and the Caribbean in the SciELO Citation Index and the Web of Science

    NARCIS (Netherlands)

    Vélez-Cuartas, G.; Lucio-Arias, D.; Leydesdorff, L.

    2016-01-01

    In this article the authors compare the visibility of Latin American and Caribbean (LAC) publications in the Core Collection indexes of the Web of Science (WoS) inlcuding Science Citation Index Expanded, Social Sciences Citation Index, and Arts & Humanities Citation Index, and the SciELO Citation

  12. 40Ar/39Ar studies of deep sea igneous rocks

    International Nuclear Information System (INIS)

    Seidemann, D.

    1978-01-01

    An attempt to date deep-sea igneous rocks reliably was made using the 40 Ar/ 39 Ar dating technique. It was determined that the 40 Ar/ 39 Ar incremental release technique could not be used to eliminate the effects of excess radiogenic 40 Ar in deep-sea basalts. Excess 40 Ar is released throughout the extraction temperature range and cannot be distinguished from 40 Ar generated by in situ 40 K decay. The problem of the reduction of K-Ar dates associated with sea water alteration of deep-sea igneous rocks could not be resolved using the 40 Ar/ 39 Ar technique. Irradiation induced 39 Ar loss and/or redistribution in fine-grained and altered igneous rocks results in age spectra that are artifacts of the experimental procedure and only partly reflect the geologic history of the sample. Therefore, caution must be used in attributing significance to age spectra of fine grained and altered deep-sea igneous rocks. Effects of 39 Ar recoil are not important for either medium-grained (or coarser) deep-sea rocks or glasses because only a small fraction of the 39 Ar recoils to channels of easy diffusion, such as intergranular boundaries or cracks, during the irradiation. (author)

  13. Geological Dating by 40 Ar - 39 Ar method

    International Nuclear Information System (INIS)

    Vollbert Romero, M.E.

    1992-01-01

    The isotope 40 K is radioactive, it decays to 40 Ar stable. The number of 40 Ar atoms produced from 40 K, permits to calculate the date of rocks and minerals. This dating technique is named 'Conventional K-Ar Dating Method'. The 40 Ar - 39 Ar dating method permits to calculate the age of rocks and minerals eliminating the limitation of the K-Ar method by calculating potassium and argon concentrations in a single measurement of the ratio of argon isotopes. In this work, the irradiation of the sample with fast neutrons in the nuclear reactor was established. 39 Ar is obtained from the induced reaction 39 K (n,p) 39 Ar. Thus the ration of 40 Ar - 39 Ar allows to obtain the date of rocks and minerals. This ratio was measured in a mass spectrometer. If the measurement of argon concentration in the sample is carried out at different increasing temperature values, it is possible to get information of paleotemperatures. The number of atoms 39 Ar is a function of the number 39 K atoms, irradiation time, neutrons flux, its energy E and the capture cross section σ of 39 K. These parameters are calculate indirectly by obtaining the so called 'J value ' by using a standard mineral with known age (HD-BI y Biot-133), this mineral is irradiated together with the unknown age sample. The values of 'J' obtained are in the interval of 2.85 a 3.03 (x 10 - 3)J/h. Rocks from 'Tres Virgenes' were dated by the method described in this work, showing an agreement with previous values of different authors. The age of this rocks are from Cenozoico era, mainly in the miocene period. (Author)

  14. Dcode.org anthology of comparative genomic tools.

    Science.gov (United States)

    Loots, Gabriela G; Ovcharenko, Ivan

    2005-07-01

    Comparative genomics provides the means to demarcate functional regions in anonymous DNA sequences. The successful application of this method to identifying novel genes is currently shifting to deciphering the non-coding encryption of gene regulation across genomes. To facilitate the practical application of comparative sequence analysis to genetics and genomics, we have developed several analytical and visualization tools for the analysis of arbitrary sequences and whole genomes. These tools include two alignment tools, zPicture and Mulan; a phylogenetic shadowing tool, eShadow for identifying lineage- and species-specific functional elements; two evolutionary conserved transcription factor analysis tools, rVista and multiTF; a tool for extracting cis-regulatory modules governing the expression of co-regulated genes, Creme 2.0; and a dynamic portal to multiple vertebrate and invertebrate genome alignments, the ECR Browser. Here, we briefly describe each one of these tools and provide specific examples on their practical applications. All the tools are publicly available at the http://www.dcode.org/ website.

  15. Lateglacial.org

    DEFF Research Database (Denmark)

    Jensen, Peter

    2012-01-01

    Lateglacial.org is an interactive, open-access online data repository and geographic research tool for the Late Glacial period of northern Europe. The database behind this website currently contains information on those localities that have yielded remains from the Late Glacial period, and is cen......Lateglacial.org is an interactive, open-access online data repository and geographic research tool for the Late Glacial period of northern Europe. The database behind this website currently contains information on those localities that have yielded remains from the Late Glacial period...

  16. Standardization of 40Ar-39Ar dating facility at KDMIPE, ONGC, Dehradun

    International Nuclear Information System (INIS)

    Rathore, S.S.; Singh, M.P.; Vijan, A.R.; Bansal, M.; Prabhu, B.N.; Misra, K.N.

    2003-01-01

    In the pursuit of acquiring state of the art technology, efforts were being made for last more than two years to establish 40 Ar- 39 Ar dating facility at KDMIPE. The 40 Ar- 39 Ar dating technique is an analytical conversion of the conventional K-Ar dating method. In this method, the sample to be dated is first irradiated in a nuclear reactor to transform a portion of 39 K to 39 Ar by the fast neutron reaction i.e. 39 K(n, p) 39 Ar. After irradiation, the sample is placed in an ultra-high vacuum system and the argon extracted from it by fusion is purified and analyzed isotopically in a mass spectrometer. The relative abundances of 40 Ar, 39 Ar, 37 Ar and 36 Ar are measured. The 40 Ar/ 39 Ar K is determined, where 40 Ar is the radiogenic argon, and 39 Ar K is the 39 Ar produced from 39 K during the irradiation. The 40 Ar/ 39 Ar K ratio is proportional to the 40 Ar/ 40 K ratio in the sample and, therefore, is proportional to age

  17. Temperature and pressure effects on 40Ar-39Ar systematics

    International Nuclear Information System (INIS)

    Ozima, M.; Kaneoka, I.; Yanagisawa, M.

    1979-01-01

    The effects of thermal and compressional treatment on 40 Ar- 39 Ar systematics have been investigated on three artificially heated biotite samples (heated for 1 hour at 700 0 C and 860 0 C in air and 700 0 C in vacuum respectively) and uniaxially compressed granite (p=1400 bar) and basalt samples (p=1660 bar). The 40 Ar- 39 Ar results for the disturbed samples are compared with those for undisturbed samples. Except for the vacuum-heating case, the effects of the disturbances may be interpreted as the combined effect of a partial loss of radiogenic 40 Ar from the sample and an incorporation of air Ar into the sample. Common diagnostic effects are (1) reduction of the total fusion age, (2) distortion of the age spectrum and, if the degree of the partial Ar loss is small (3) approximate preservation of the isochron age, and (4) reduction of the intercept value ( 40 Ar/ 36 Ar) in the isochron plot. The features observed in the age spectra of artificially disturbed samples are rather common in geologically disturbed samples, suggesting that the artificial disturbances simulate the effects of geological disturbances on 40 Ar- 39 Ar systematics. (Auth.)

  18. The ChArMEx database

    Science.gov (United States)

    Ferré, Helene; Belmahfoud, Nizar; Boichard, Jean-Luc; Brissebrat, Guillaume; Descloitres, Jacques; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Mastrorillo, Laurence; Mière, Arnaud; Vermeulen, Anne

    2014-05-01

    observations or products that will be provided to the database. - A search tool to browse the catalogue using thematic, geographic and/or temporal criteria. - A shopping-cart web interface to order in situ data files. - A web interface to select and access to homogenized datasets. Interoperability between the two data centres is being set up using the OPEnDAP protocol. The data portal will soon propose a user-friendly access to satellite products managed by the ICARE data centre (SEVIRI, TRIMM, PARASOL...). In order to meet the operational needs of the airborne and ground based observational teams during the ChArMEx 2012 and 2013 campaigns, a day-to-day chart and report display website has been developed too: http://choc.sedoo.org. It offers a convenient way to browse weather conditions and chemical composition during the campaign periods.

  19. European Embedding of Passive Houses. www.europeanpassivehouses.org

    Energy Technology Data Exchange (ETDEWEB)

    Elswijk, M.; Kaan, H. (eds.) [and others

    2008-05-15

    The passive house concept has become a European wide accepted solution to reach a significant energy demand reduction in the built environment. The European Commission has published the ambition to construct newly built ho uses in 2015 accordingly to the passive ho use standard. In most project participating countries this ambition is shared. With the support of the Intelligent Energy Europe program this project 'Promotion of European Passive Houses' (PEP-project) contributed to achieve this ambition to clear the first market barriers internationally to reach the status 'Business As Usual' for passive houses in 2015. The PEP project aimed at the development of easy accessible web based documentation for stakeholders in the building process to solve national market introduction barriers regarding the passive house concept. The project also aimed at the distribution of this information via international and national workshops, seminars and conferences. It can be concluded that the PEP-project has been successful. All participating countries made significant progress in the societal embedding process of passive houses and in most countries the passive house concept is on the brink of breaking through nationally. Further, the PEP-project contributed successfully in the internationalisation of the Internal Passive House Conference and fixed the definition of a passive house for three geographical European regions. Finally, the PEP website with its wealth of information was a powerful tool for promotion of passive houses in Europe. In order to increase the implementation efficiency of the passive house concept it is recommended to develop additional information packages concerning passive house solutions for offices, schools and social homes (e.g. architectural examples, organisational issues); passive house renovations; financial schemes for passive houses; performance oriented quality approach for the design and construction process; industrial prefab construction of passive elements and practical training programs for craftsmen, to architects, engineers and developers. Further research is recommended to identify the relation between hygienics required of ventilation systems and comfort and health. Finally, it is recommended to start the implementation of the certification schemes for passive houses.

  20. Places to Go: Sakai|http://www.sakaiproject.org/

    Science.gov (United States)

    Downes, Stephen

    2006-01-01

    Stephen Downes continues his examination of open source learning management systems (LMSs) with a visit to Sakai's Web site. While Sakai's Web site is not particularly easy to navigate, it provides access to a large community and constellation of related online learning products and initiatives. Visitors can visit discussion forums to ask…

  1. Maturação de Compostos Orgânicos de Resíduos Agroindustriais

    Directory of Open Access Journals (Sweden)

    Rafaela Alves Pereira

    2013-07-01

    Full Text Available Os resíduos agroindustriais geralmente apresentam grandes concentrações de materiais orgânicos que, se manejados de forma inadequada, podem poluir e/ou contaminar o solo, a água e o ar. A técnica de compostagem tem se mostrado um processo eficiente na busca pela minimização da problemática ambiental associada aos resíduos orgânicos e na redução do volume de resíduos descartados em lixões e aterros sanitários. O principal objetivo deste trabalho consiste na utilização de parâmetros físico-químicos para verificar a maturação de compostos orgânicos obtidos a partir de resíduos agroindustriais da região de Pombal, um município localizado no semiárido paraibano. Para obtenção dos compostos orgânicos, cascas de bananas, estercos ovinos e podas de marmeleiro e jurema-preta foram triturados e misturados para montar duas pilhas de compostagem, sendo uma depositada em solo compactado e outra sobre um pátio pavimentado com concreto. Os parâmetros utilizados na avaliação da maturação foram: temperatura, relação C/N, condutividade elétrica, pH e demanda química de oxigênio. Os resultados sugerem que os compostos orgânicos estudados estão maturados, indicando que estes simples métodos são considerados seguros para verificação de processos de compostagem conduzidos em regiões sujeitas às condições semiáridas. 

  2. Uudised : Tasuta netialbum. Edetabel

    Index Scriptorium Estoniae

    2005-01-01

    Kunstnik ja muusik Andres Lõo andis välja sooloprojekti Ars Intel esimese albumi "Monitor" (http://www.looming.org/arsintel). Raadio 2 eetris on taas Eesti albumimüügi edetabel: top 10 (kodu- ja välismaalt) pannakse kokku suuremate poodide müügiandmete põhjal ja top 20 raadiokuulajate poolt internetis hääletatud tulemuste põhjal

  3. WWW chart of the nuclides

    International Nuclear Information System (INIS)

    Huang Xiaolong; Zhou Chunmei; Zhuang Youxiang; Zhao Zhixiang; Golashvili, T.V.; Chechev, V.P.

    2000-01-01

    WWW chart of the nuclides was established on the basis of the latest evaluations of nuclear structure and decay data. By viewing WWW chart of the nuclides, one can retrieve the fundamental data of nuclide such as atomic mass, abundance, spin and parity; the decay mode, branching ratio, half-life and Q-value of radioactive nuclide, energy and intensity of strong γ-ray, etc. The URL (Uniform Resource Locator) of WWW chart of the nuclides is: http://myhome.py.gd.cn/chart/index,asp

  4. Integrative Functional Genomics for Systems Genetics in GeneWeaver.org.

    Science.gov (United States)

    Bubier, Jason A; Langston, Michael A; Baker, Erich J; Chesler, Elissa J

    2017-01-01

    The abundance of existing functional genomics studies permits an integrative approach to interpreting and resolving the results of diverse systems genetics studies. However, a major challenge lies in assembling and harmonizing heterogeneous data sets across species for facile comparison to the positional candidate genes and coexpression networks that come from systems genetic studies. GeneWeaver is an online database and suite of tools at www.geneweaver.org that allows for fast aggregation and analysis of gene set-centric data. GeneWeaver contains curated experimental data together with resource-level data such as GO annotations, MP annotations, and KEGG pathways, along with persistent stores of user entered data sets. These can be entered directly into GeneWeaver or transferred from widely used resources such as GeneNetwork.org. Data are analyzed using statistical tools and advanced graph algorithms to discover new relations, prioritize candidate genes, and generate function hypotheses. Here we use GeneWeaver to find genes common to multiple gene sets, prioritize candidate genes from a quantitative trait locus, and characterize a set of differentially expressed genes. Coupling a large multispecies repository curated and empirical functional genomics data to fast computational tools allows for the rapid integrative analysis of heterogeneous data for interpreting and extrapolating systems genetics results.

  5. 39Ar/Ar measurements using ultra-low background proportional counters

    International Nuclear Information System (INIS)

    Hall, Jeter; Aalseth, Craig E.; Bonicalzi, Ricco M.; Brandenberger, Jill M.; Day, Anthony R.; Humble, Paul H.; Mace, Emily K.; Panisko, Mark E.; Seifert, Allen

    2016-01-01

    Age-dating groundwater and seawater using the 39 Ar/Ar ratio is an important tool to understand water mass-flow rates and mean residence time. Low-background proportional counters developed at Pacific Northwest National Laboratory use mixtures of argon and methane as counting gas. We demonstrate sensitivity to 39 Ar by comparing geological (ancient) argon recovered from a carbon dioxide gas well and commercial argon. The demonstrated sensitivity to the 39 Ar/Ar ratio is sufficient to date water masses as old as 1000 years. - Highlights: • 39 Ar/Ar age dating is important for understanding environmental water migration. • Ultra low background proportional counters have been developed. • 39 Ar is detected in atmospheric argon at a rate of 70.3 counts per day. The demonstrated background is 166 counts per day. • Age dating is possible for water with underground residence time of up to 1000 years.

  6. 40Ar/39Ar age calibration against counted annuallayers

    DEFF Research Database (Denmark)

    Storey, Michael; Stecher, Ole

    2008-01-01

    The 40Ar/39Ar method, based on the decay of the naturally occurring radioactive isotope 40K, is capable of producing ages with precision better than ± 0.1 %. However, accuracy is limited to no better than 1 % mainly due to the relatively large uncertainty in the 40K decay constants. One approach...... worth exploring for an improved absolute age basis for the 40Ar/39Ar system is through cross-calibration with counted annual layers (e.g. tree rings, varves and ice cores). North Atlantic Ash Zone (NAAZ) II is found within the dated part of the annual Greenland ice core record. NAAZ II has been...... correlated to the Icelandic peralkaline rhyolitic Thorsmörk ignimbrite. We will present preliminary 40Ar/39Ar results on the age of this eruption...

  7. 40Ar/39Ar and K-Ar dating of altered glassy volcanic rocks: the Dabi Volcanics, P.N.G

    International Nuclear Information System (INIS)

    Walker, D.A.; McDougall, I.

    1982-01-01

    K-Ar and 40 Ar/ 39 Ar ages have been determined for altered submarine tholeiitic and boninite (high-Mg andesite) lavas from the Dabi Volcanics, Cape Vogel Peninsula, Papua New Guinea. 40 Ar/ 39 Ar whole rock total fusion and plateau ages identify a Late Paleocene age for the tholeiitic lavas (58.9 +- 1.1 Ma), and also for the boninitic lavas (58.8 +- 0.8 Ma). Apparent K-Ar ages for the same samples range from 27.2 +- 0.7 to 63.9 +- 4.5 Ma, and young K-Ar ages for glassy boninites are probably due to variable radiogenic 40 Ar( 40 Ar*) loss. These new ages effectively reconcile previously ambiguous age data for the Dabi Volcanics, and indicate contemporaneous tholeiitic and boninitic volcanism occurring in southeast PNG during the Late Paleocene. Smectites, developed as alteration products after glass in oceanic lavas commonly do not retain 39 Ar during or subsequent to irradiation, but in some cases may contain 40 Ar*. The results are discussed. (author)

  8. 40Ar-39Ar stepheating studies of clay concentrates from Irish orebodies

    International Nuclear Information System (INIS)

    Halliday, A.N.

    1978-01-01

    40 Ar- 39 Ar step heating analyses of clay concentrates from the Gortdrum and Tynagh orebodies (Ireland) previously dated by conventional K-Ar, indicate major losses of 39 Ar (32 to 45%) and rad. 40 Ar (25 to 35%) during the irradiation. The proportion of rad. 40 Ar loss, unlike that of 39 Ar, increases with J-value. The difference between 39 Ar and rad. 40 Ar proportion losses is related to the mineralogy and grain intimacy. These also affect the stepwise release patterns - the Gortdrum concentrates yield age spectra very consistent with 39 Ar recoil predictions, whereas the Tynagh concentrates in which the grains are intimately intergrown, show no clear evidence for 39 Ar recoil depletion in the K-rich phases. The difference is resolvable if illite argon release is not a simple volume diffusion type process under vacuum conditions. (author)

  9. Aprovechamiento de residuos sólidos en un sistema hidro-orgánico de agricultura urbana

    Directory of Open Access Journals (Sweden)

    Consuelo Montes Rojas

    2008-12-01

    Full Text Available La investigación tuvo por objeto diseñar un sistema hidroorgánico de producción de hortalizas en áreas pequeñas, con el fin de contribuir a la seguridad alimentaria de la población urbana y al aprovechamiento de los residuos sólidos de la ciudad de Popayán. Se diseñó un sistema a partir de material reciclado y se evaluó utilizando tres tratamientos como fuente nutricional (Lixiviado orgánico, Lixiviado orgánico suplementado, solución nutritiva común y como indicador biológico cilantro (Coriandrum sativum l.. La respuesta de las plantas fue evaluada por crecimiento y desarrollo. El sistema para producción urbana de hortalizas permitió obtener producciones hasta de 627 g m-2, superando la producción en agricultura tradicional (227 g. La mejor fuente nutricional fue la solución nutritiva comercial.

  10. Influence of residual Ar+ in Ar cluster ion beam for DLC film formation

    International Nuclear Information System (INIS)

    Kitagawa, Teruyuki; Miyauchi, Kazuya; Toyoda, Noriaki; Kanda, Kazuhiro; Ikeda, Tokumi; Tsubakino, Harushige; Matsuo, Jiro; Matsui, Shinji; Yamada, Isao

    2003-01-01

    In order to study the influences of residual Ar monomer ion (Ar + ) on sp 2 content and hardness of diamond like carbon (DLC) films formed by Ar cluster ion beam assisted deposition, Ar cluster ion, Ar + and their mixed ions (Ar cluster ion and Ar + ) bombardments were performed during evaporation of C 60 . From near edge X-ray absorption fine structure (NEXAFS) and Raman spectroscopy measurements, lower sp 2 content in the carbon films was obtained with Ar cluster ion bombardment than that with Ar + and mixed ion. Furthermore higher hardness and smooth surface were shown with Ar cluster ion bombardments. Therefore it was important to reduce Ar + in Ar cluster ion beams to obtain hard DLC films with flat surface

  11. Effects of shock pressure on 40Ar-39Ar radiometric age determinations

    International Nuclear Information System (INIS)

    Davis, P.K.

    1977-01-01

    The relation of shock to the drop in the 40 *Ar/ 39 *Ar ratio seen at high release temperatures in some neutron-irradiated lunar samples is investigated through measurements of the 40 *Ar/ 39 *Ar ratio in gas samples released by stepwise heating of rock samples previously subjected to shock, either in the laboratory or in nature. Explosives were used to shock solid pieces and powder of a basalt from a diabase dike in Liberia to calculated pressures of 65, 150 and 270 kbar. These, an unshocked sample of the powder, two naturally shocked samples from the Brent impact crater in Canada, one unshocked sample from near the crater, and appropriate monitors were irradiated. Ar from stepwise heating was analyzed. The unshocked basalt shows a good 40 *Ar/ 39 *Ar plateau at age 198 +-9 m.y. in agreement with a previous result of 186 +- 2 m.y. The shocked samples contain varying amounts of implanted atmospheric Ar, the isotopes of which have experienced mass fractionation. This effect is small enough in four samples so that the linearity of their graphs of 39 *Ar/ 40 Ar vs 36 Ar/ 40 Ar is evidence of a plateau. The ages of these samples are then 201 +- 10, 205 +- 12 and 201 +-9 m.y. It appears that the shock has had little effect on the 40 Ar- 39 Ar age spectrum, although the release patterns of the 39 *Ar are shifted downward by the order of 200 0 C. Shock implantation of Ar was at lower shock pressure, in the presence of less Ar, and into a less porous material than previously demonstrated. The Brent Crater samples do not all show good plateaus, but do indicate an age of 420 m.y. for the crater event and 795 +- 24 m.y. for the rock formation, in agreement with previous results. None of the 40 *Ar/ 39 *Ar profiles shows a drop at high temperature, but a possible role of shock implantation of Ar is indicated in the production of this effect. Further experiments are suggested. (author)

  12. Validation of argo data in the Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Pankajakshan, T.; Muraleedharan, P.M.; Gopalakrishna, V.V.; Reddy, G.V.; Ratnakaran, L.; Revichandran, C.; Murty, V.S.N.

    Gayana (Concepción) - VALIDATION OF ARGO DATA IN THE INDIAN OCEA... 8/11/2006http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-65382004000300025&lng=... susceptible to fouling and associated drift because of the possible change... initial profiles (profiles 1 and 2). Figure-1b represents the same as that in figure-1a, but for 29 match-ups involving profile numbers 5 and above. Page 2 of 5Gayana (Concepción) - VALIDATION OF ARGO DATA IN THE INDIAN OCEA... 8/11/2006http://www...

  13. Electron scattering from 36Ar and 40Ar

    International Nuclear Information System (INIS)

    Finn, J.M.

    1975-01-01

    The argon isotopes, 36 Ar and 40 Ar, have been investigated using electron scattering at the high-resolution Linac facilities of the National Bureau of Standards. Both elastic scattering and scattering to low-lying states have been observed. A high-pressure, low-volume gas target cell was designed and developed for this experiment. The cell features a transmission geometry and has resolution comparable to solid targets. Spectra were obtained at incident beam energies ranging from 65 to 115 MeV at scattering angles of 92.5 0 and 110 0 . Values obtained for the rms charge radii are 3.327 +- 0.015 and 3.393 +- 0.015 fm for 36 Ar and 40 Ar respectively. A sensitive measurement was made of the difference in the two radii yielding a value of Δ r = 0.079 +- 0.006 fm. The inelastic levels observed are the 1.97 (2 + ) and 4.18 MeV (3 - ) levels in 36 Ar, and the 1.46 (2 + ), 2.52 (2 + ), 3.21 (2 + ), and 3.68 MeV (3 - ) levels in 40 Ar. A Tassie model analysis was made of the inelastic transitions in the DWBA approximation and transition strengths of these levels were extracted

  14. Baicalein suppresses the androgen receptor (AR)-mediated prostate cancer progression via inhibiting the AR N-C dimerization and AR-coactivators interaction.

    Science.gov (United States)

    Xu, Defeng; Chen, Qiulu; Liu, Yalin; Wen, Xingqiao

    2017-12-01

    Androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and progression. Androgen deprivation therapy with antiandrogens to reduce androgen biosynthesis or prevent androgens from binding to AR are widely used to suppress AR-mediated PCa growth. However, most of ADT may eventually fail with development of the castration resistance after 12-24 months. Here we found that a natural product baicalein can effectively suppress the PCa progression via targeting the androgen-induced AR transactivation with little effect to AR protein expression. PCa cells including LNCaP, CWR22Rv1, C4-2, PC-3, and DU145, were treated with baicalein and luciferase assay was used to evaluate their effect on the AR transactivation. Cell growth and IC 50 were determined by MTT assay after 48 hrs treatment. RT-PCR was used to evaluate the mRNA levels of AR target genes including PSA, TMPRSS2, and TMEPA1. Western blot was used to determine AR and PSA protein expression. The natural product of baicalein can selectively inhibit AR transactivation with little effect on the other nuclear receptors, including ERα, and GR. At a low concentration, 2.5 μM of baicalein effectively suppresses the growth of AR-positive PCa cells, and has little effect on AR-negative PCa cells. Mechanism dissection suggest that baicalein can suppress AR target genes (PSA, TMPRSS2, and TMEPA1) expression in both androgen responsive LNCaP cells and castration resistant CWR22Rv1 cells, that may involve the inhibiting the AR N/C dimerization and AR-coactivators interaction. Baicalein may be developed as an effective anti-AR therapy via its ability to inhibit AR transactivation and AR-mediated PCa cell growth.

  15. TiArA: a virtual appliance for the analysis of Tiling Array data.

    Directory of Open Access Journals (Sweden)

    Jason A Greenbaum

    2010-04-01

    Full Text Available Genomic tiling arrays have been described in the scientific literature since 2003, yet there is a shortage of user-friendly applications available for their analysis.Tiling Array Analyzer (TiArA is a software program that provides a user-friendly graphical interface for the background subtraction, normalization, and summarization of data acquired through the Affymetrix tiling array platform. The background signal is empirically measured using a group of nonspecific probes with varying levels of GC content and normalization is performed to enforce a common dynamic range.TiArA is implemented as a standalone program for Linux systems and is available as a cross-platform virtual machine that will run under most modern operating systems using virtualization software such as Sun VirtualBox or VMware. The software is available as a Debian package or a virtual appliance at http://purl.org/NET/tiara.

  16. /sup 40/Ar//sup 39/Ar and K-Ar dating of altered glassy volcanic rocks: the Dabi Volcanics, P. N. G

    Energy Technology Data Exchange (ETDEWEB)

    Walker, D.A. (Australian National Univ., Canberra. Dept. of Geology); McDougall, I. (Australian National Univ., Canberra. Research School of Earth Sciences)

    1982-11-01

    K-Ar and /sup 40/Ar//sup 39/Ar ages have been determined for altered submarine tholeiitic and boninite (high-Mg andesite) lavas from the Dabi Volcanics, Cape Vogel Peninsula, Papua New Guinea. /sup 40/Ar//sup 39/Ar whole rock total fusion and plateau ages identify a Late Paleocene age for the tholeiitic lavas (58.9 +- 1.1 Ma), and also for the boninitic lavas (58.8 +- 0.8 Ma). Apparent K-Ar ages for the same samples range from 27.2 +- 0.7 to 63.9 +- 4.5 Ma, and young K-Ar ages for glassy boninites are probably due to variable radiogenic /sup 40/Ar(/sup 40/Ar*) loss. These new ages effectively reconcile previously ambiguous age data for the Dabi Volcanics, and indicate contemporaneous tholeiitic and boninitic volcanism occurring in southeast PNG during the Late Paleocene. Smectites, developed as alteration products after glass in oceanic lavas commonly do not retain /sup 39/Ar during or subsequent to irradiation, but in some cases may contain /sup 40/Ar*. The results are discussed.

  17. Single electron capture by state-prepared Ar2+ projectiles in Ar

    International Nuclear Information System (INIS)

    Puerta, J.; Huber, B.A.

    1985-03-01

    Electron capture by state-selected Ar 2+ projectiles in Ar has been studied at low collision energies ( 2+ ions are measured explaining existing discrepancies of partial and total cross sections in the Ar 2+ /Ar collision system. Although highly excited metastable ions ( 5 D 4 0 , 3 F 4 0 ) represent a minor contamination of a non-prepared Ar 2+ beam (proportional1%), their contributions are found to dominate the capture process due to cross section values larger than 10 -15 cm 2 . (orig.)

  18. On mechanism of Ar(3p54p) states excitation in low-energy Ar-Ar collisions

    International Nuclear Information System (INIS)

    Kurskov, S Y; Kashuba, A S

    2009-01-01

    The present work is devoted to study of Ar(3p 5 4p) states excitation in binary low-energy Ar-Ar collisions. The results of the experimental investigation of excitation cross sections of Ar I 4p'[l/2] 1 , 4p'[3/2] 1 , 4p'[3/2] 2 and 4p[3/2] 2 levels in the collision energy range from threshold up to 500 eV (cm) and degree of polarization for 4s[3/2] 2 0 -4p'[l/2] 1 and 4s[3/2] 2 0 -4p[3/2] 2 transitions in this energy range are represented.

  19. First-principles calibration of 40Ar/39Ar mineral standards and complete extraction of 40Ar* from sanidine

    Science.gov (United States)

    Morgan, L. E.; Kuiper, K.; Mark, D.; Postma, O.; Villa, I. M.; Wijbrans, J. R.

    2010-12-01

    40Ar/39Ar geochronology relies on comparing argon isotopic data for unknowns to those for knowns. Mineral standards used as neutron fluence monitors must be dated by the K-Ar method (or at least referenced to a mineral of known K-Ar age). The commonly used age of 28.02 ± 0.28 Ma for the Fish Canyon sanidine (FCs) (Renne et al., 1998) is based upon measurements of radiogenic 40Ar in GA1550 biotite (McDougall and Roksandic, 1974), but underlying full data were not published (these measurements were never intended for use as an international standard), so uncertainties are difficult to assess. Recent developments by Kuiper et al. (2008) and Renne et al. (2010) are limited by their reliance on the accuracy of other systems. Modern technology should allow for more precise and accurate calibration of primary K-Ar and 40Ar/39Ar standards. From the ideal gas law, the number of moles of 40Ar in a system can be calculated from measurements of pressure, volume, and temperature. Thus we have designed and are proceeding to build a pipette system to introduce well-determined amounts of 40Ar into noble gas extraction lines and mass spectrometers. This system relies on components with calibrations traceable to SI unit prototypes, including a diaphragm pressure gauge (MKS Instruments), thermocouples, and a “slug” of an accurately determined volume to be inserted into the reservoir for volume determinations of the reservoir and pipette. The system will be renewable, with a lifetime of ca. 1 month for gas in the reservoir, and portable, to permit interlaboratory calibrations. The quantitative extraction of 40Ar* from the mineral standard is of highest importance; for sanidine standards this is complicated by high melt viscosity during heating. Experiments adding basaltic “zero age glass” (ZAG) to decrease melt viscosity are underway. This has previously been explored by McDowell (1983) with a resistance furnace, but has not been quantitatively addressed with laser heating

  20. Structural, K-Ar and 40Ar-39Ar age studies of adularia K-feldspars from the Lizard Complex, England

    International Nuclear Information System (INIS)

    Halliday, A.N.; Mitchell, J.G.

    1976-01-01

    Conventional K-Ar analyses of fifteen adularia feldspars from the Lizard Complex yield ages between 181+-2 Ma and 220+-3 Ma (with one exception from Holseer Cove yielding an age of 156+-3 Ma). The feldspars are dominantly monoclinic but most contain a minor but constant proportion of triclinic material with variable triclinicity. An inverse correlation exists between triclinicity and K-Ar age interpreted as representing argon loss related to the structural state. Extrapolation of the data to zero triclinicity indicates a true age of 210-220 Ma. 40 Ar- 39 Ar stepwise degassing analyses yield plateau ages related to the K-Ar ages and not the crystallization age. The results can be explained in terms of postcrystallization Al-Si ordering resulting in argon loss from lattice sites which under normal diffusion conditions requires a range of activation energies. The Holseer Cove sample is monoclinic and an 40 Ar- 39 Ar stepheating analysis suggests a later crystallization at 160-170 Ma. Neither primary crystallization nor spontaneous ordering through time explain the origin of the triclinic adularia. It is suggested that ordering has been induced by the passage of low-temperature alkaline solutions at a subsequent point in geological time. Argon loss by ordering could explain the low ages found using both K-Ar and 40 Ar- 39 Ar stepheating methods when applied to feldspars in general. The 210-220 Ma, and 160-170 Ma hydrothermal events affected much of southwest England and are probably related to major geotectonic movements in western Europe. (Auth.)

  1. Oral bioavailability assessment and intestinal lymphatic transport of Org 45697 and Org 46035, two highly lipophilic novel immunomodulator analogues.

    Science.gov (United States)

    Caliph, Suzanne M; Faassen, W A Fried; Vogel, Gerard M; Porter, Christopher J H

    2009-08-01

    Org 45697 (MW 600.7, clogP 7.92, soybean oil solubility 50 mg/g) and Org 46035 (MW 601.6, clog P 8.46, soybean oil solubility 40 mg/g) are two poorly water soluble ( 5 fold) after oral administration in a long chain triglyceride lipid (olive oil) formulation. Subsequent studies have explored the potential for solubilising formulations, including lipid-based formulations, to enhance the oral bioavailability of Org 45697 and Org 46035 and secondly to explore the potential contribution of intestinal lymphatic transport to intestinal absorption. The experimental data show that solubilising formulations may provide for significant increases in oral bioavailability for Org 45697 and Org 46035 and that after co-administration with lipid, 35-50% of the absorbed dose may be transported to the systemic circulation via the intestinal lymph. Interestingly, the lymphatic transport of the less lipid soluble analogue, Org 46035 was approximately 40% lower than that of Org 45697 suggesting that relatively subtle differences in lipid solubility can have significant impact on the extent of lymphatic transport.

  2. Geochronology and thermochronology by the 40Ar/39Ar method

    International Nuclear Information System (INIS)

    McDougall, I.; Harrison, T.M.

    1988-01-01

    This work is a response to the authors' belief that there is a need for a monograph on 40 Ar/ 39 Ar dating to provide concise knowledge concerning the application of this method to geological studies. They aim to provide a reasonably comprehensive but by no means exhaustive coverage of the principles and practices of 40 Ar/ 39 Ar dating, with emphasis on interpretation of results. In attempting to provide an overview of the current state of knowledge, they commonly cite examples from the available literature. They draw rather heavily upon their own work, because they feel comfortable with their own examples. (author)

  3. Behaviour of AR glass fibre for building structural applications

    Directory of Open Access Journals (Sweden)

    Miravete, A.

    2005-12-01

    éticas, lo cual abre el espectro de las aplicaciones estructurales del material compuesto fibra de vidrio con matriz orgánica como refuerzo dentro del hormigón. En este artículo se van a estudiar las propiedades mecánicas de los materiales compuestos de fibra de vidrio AR. Primeramente se estudiará el comportamiento de este tipo de fibra bajo una solicitación de corrosión bajo tensión. Se comparará su pérdida de masa frente a las fibras de vidrio tipo E, C y sin boro. A continuación se describirán los ensayos mecánicos de flexión 3 puntos y viga corta llevados a cabo con laminados fibra de vidrio AR/poliéster con objeto de determinar su módulo de Young y sus resistencias tanto a flexión como a cortadura interlaminar. Se compararán los resultados de estos ensayos con los obtenidos para el material compuesto de fibra de vidrio E/poliéster y se analizará su utilización como material estructural en el ámbito de la construcción.

  4. A flavor of 40Ar-39Ar geochronology research at lIT Bombay

    International Nuclear Information System (INIS)

    Pande, Kanchan

    2017-01-01

    Geochronology based on radiogenic isotopes has become an invaluable tool in earth sciences. Several radioactive parent-daughter systems of varying half-lives such as Rb-Sr, Sm-Nd, K-Ar have been traditionally used by researchers for determining the timing of geological and planetary processes. 40 Ar- 39 Ar dating, a variant of the K-Ar system, is a well-established and versatile method of determining the eruptive ages of volcanic rocks and the ∼150-500° C thermal histories of a variety of more slowly cooled igneous and metamorphic rocks. In the 40 Ar- 39 Ar method the sample is irradiated by fast neutrons in a nuclear reactor to convert some of 39 K into 39 Ar. The fixed natural ratio 39 K/ 40 K provides estimate for the parent 40 K by measuring 39 Ar. In order to know the conversion factor of 39 K to 39 Ar and to take care of other nuclear interfering reactions a sample of known K-Ar age is irradiated along with the unknown. The age of the unknown is then derived by comparison with the monitor sample of known age

  5. Vector analyzing power and cross section for the reactions 40Ar(d(pol),p)41Ar and 40Ar(d(pol),t)39Ar

    International Nuclear Information System (INIS)

    Sen, S.; Darden, S.E.; Yoh, W.A.; Berners, E.D.

    1975-01-01

    Angular distributions of vector analyzing power and cross section for the reactions 40 Ar(d,p) 41 Ar and 40 Ar(d,t) 39 Ar have been measured at an incident deuteron energy of 14.83 MeV. The bound-state data in the (d,p) reaction and the (d,t) data are compared to DWBA calculations. The data for the neutron-unbound states are analyzed in the framework of the DWBA using (i) a form factor for weakly bound neutron and (ii) a resonance form factor, following the approach of Vincent and Fortune. The j-dependence of the (d,p) vector analyzing power permits definite spin-parity assignments to be made for 19 neutron-bound and 4 neutron unbound states in 41 Ar with excitation energy up to 6.57 MeV. Tentative Jsup(π) assignments have been made for 3 states. The l-value for the 5.62 MeV states has been determined. Data for the observed unbound states are found to be equally well reproduced by the type (i) calculations as by the type (ii) calculations. The (d,t) vector cnalyzing power data show definite J-dependence although not as strongly as in the (d,p) reaction. For relatively weakly excited states a pre-knowledge of the l-value of the transition is desirable for an unambiguous spin assignment. In general, the J-dependence in the (d,t) vector analyzing power can be utilized for definitive Jsup(π) assignments. On this basis, Jsub(π) values have been assigned for seven states in 39 Ar with excitation energies up to 4.47MeV excitation. Possible spin values for three other states are suggested. Spectroscopic factors fo the states in 41 Ar and 39 Ar have been extracted and are in fair agreement with those obtained by other workers. (Auth.)

  6. Spectroscopic analysis of visible and near UV light emitted by Ar7+ and Ar6+ ions produced in Ar8+-He and Ar8+-H2 collisions at 120 keV

    International Nuclear Information System (INIS)

    Boduch, P.; Chantepie, M.; Hennecart, D.; Husson, X.; Kucal, H.; Lecler, D.; Stolterfoht, N.; Druetta, M.; Fawcett, B.; Wilson, M.

    1992-01-01

    A spectroscopic analysis of light emitted in the 2000-6000A wavelength range by Ar 7+ and Ar 6+ ions produced in Ar 8+ -He and Ar 8+ -H 2 collisions at 120 keV is performed. Well resolved fine structure components of 5s-5p and 5p-5d transitions in Ar VIII following single electron capture are precisely measured. Predominant lines due to double electron capture are observed. In particular, strong lines observed both in Ar 8+ -He and Ar 8+ -H 2 collisions are attributed to Ryberg transitions 3snl-3sn'l' in Ar VII. Attempts at identifications are made for the transition 3dnl-3dn'l' (n=4, 5) with the help of ab initio calculations. Photon emission cross sections for individual lines are determined from the measured data. (orig.)

  7. 40Ar/39Ar dating of pyrite

    International Nuclear Information System (INIS)

    York, D.; Masliwec, A.; Kuybida, P.; Hanes, J.A.; Hall, C.M.; Kenyon, W.J.; Spooner, E.T.C.; Scott, S.D.

    1982-01-01

    To overcome difficulties encountered in the customary method of determining the age of mineralization of sulphide ore deposits by analysing silicate material, the sulphide minerals themselves have been examined to see if they contained sufficient potassium and argon for 40 Ar/ 39 Ar age determination. Initial results indicate that this is the case for pyrite from the Geco ore body in northwestern Ontario, Canada. (U.K.)

  8. From Scientists to the Public: Communicating Science through Blogs on oceanbites.org and envirobites.org

    Science.gov (United States)

    Lemon, M. G.; McDonough, C. A.; Schifman, L. A.

    2017-12-01

    Science communication is increasingly important. Our world is facing difficult environmental challenges that can only be addressed if an understanding of the basic scientific principles exists. With this in mind, we founded oceanbites.org in 2013, and recently (August 2017) also started envirobites.org. For both blogs, graduate students, postdoctoral researchers, and science professionals come together to write and edit easy-to-read, compelling summaries of recent, cutting-edge research papers in environmental science or oceanography and make them accessible to non-experts. We want to share our passion for research with all non-scientists who are interested to learn more about the environment and our oceans: This ranges in scale from identifying science problems and solutions in cities to explaining the complex environmental challenges facing our planet as a whole. Because science is also about identifying and applying technologies to address these challenges, we also cover some success stories! For envirobites.org, topics of posts include science in and for cities, global transport of pollutants, toxic effects of pollution, climate change, and environmental remediation. Oceanbites.org covers topics ranging from chemical, to biological, and physical oceanography. Currently, oceanbites.org has 24 writers and publishes posts daily, whereas envirobites.org has 26 writers and we publish posts on our blog three times per week. We hope to recruit more members and editors, but most of all, increase our readership to make a big splash in the communication of science to the public, whether we reach K-12 classrooms or living rooms.

  9. Ar-40/Ar-39 Studies of Martian Meteorite RBT 04262 and Terrestrial Standards

    Science.gov (United States)

    Park, J.; Herzog, G. F.; Turrin, B.; Lindsay, F. N.; Delaney, J. S.; Swisher, C. C., III; Nagao, K.; Nyquist, L. E.

    2014-01-01

    Park et al. recently presented an Ar-40/Ar-39 dating study of maskelynite separated from the Martian meteorite RBT 04262. Here we report an additional study of Ar-40/Ar-39 patterns for smaller samples, each consisting of only a few maskelynite grains. Considered as a material for Ar-40/Ar-39 dating, the shock-produced glass maskelynite has both an important strength (relatively high K concentration compared to other mineral phases) and some potentially problematic weaknesses. At Rutgers, we have been analyzing small grains consisting of a single phase to explore local effects that might be averaged and remain hidden in larger samples. Thus, to assess the homogeneity of the RBT maskelynite and for comparison with the results of, we analyzed six approx. 30 microgram samples of the same maskelynite separate they studied. Furthermore, because most Ar-40/Ar-39 are calculated relative to the age of a standard, we present new Ar-40/Ar-39 age data for six standards. Among the most widely used standards are sanidine from Fish Canyon (FCs) and various hornblendes (hb3gr, MMhb-1, NL- 25), which are taken as primary standards because their ages have been determined by independent, direct measurements of K and A-40.

  10. Proceedings of the Department of Defense (DoD) Symposium. DoD Entomology: Global, Diverse, and Improving Public Health

    Science.gov (United States)

    2010-12-14

    for both the USDA-ARS and competitive grant recipients is on the AFPMB web site at http://www.afpmb.org/pubs/dwfp/publicatio ns.htm. Competitive...including USAMRU-K studies on the ecology of highland malaria vectors, Walter Reed Biosystematics Unit publications, and Web -based mosquito identification...XI de Población y VI de Vivienda, Sistema de Consulta de Resultados Censales, Cuadros Estadísticos. Available at: http://desa.inei.gob.pe

  11. Automated Herbarium Specimen Identification using Deep Learning

    OpenAIRE

    Carranza-Rojas, Jose; Joly, Alexis; Bonnet, Pierre; Goëau, Hervé; Mata-Montero, Erick

    2017-01-01

    Hundreds of herbarium collections have accumulated a valuable heritage and knowledge of plants over several centuries (Page et al. 2015). Recent initiatives, such as iDigBio (https://www.idigbio.org), aggregate data from and images of vouchered herbarium sheets (and other biocollections) and make this information available to botanists and the general public worldwide through web portals. These ambitious plans to transform and preserve these historical biodiversity data into digital format ar...

  12. 37Ar and 39Ar in meteorites and the spatial cosmic ray gradient

    International Nuclear Information System (INIS)

    Heusser, G.; Schaeffer, O.A.

    1977-01-01

    Cosmic-ray-produced 37 Ar (tsub(1/2) = 35 days), and 39 Ar (tsub(1/2) = 269 years) in the Fe-Ni phase of meteorites have been studied in connection with their implications for the radial gradient of cosmic ray particles. For the chondrite, Canon City, which fell on October 27, 1973, 20.1 +- 1.5 dpm/kg FeNi of 37 Ar and 22.5 +- 1.4 dpm/kg FeNi of 39 Ar was found. Usually, the 37 Ar/ 39 Ar ratio is used to deduce a spatial gradient. However, 37 Ar data reported in the literature are inconsistent. They fluctuate much more than could be accounted for by different orbits and the anticipated correlation with the cosmic ray neutron registrations is rather weak. Consequently, the 37 Ar/ 39 Ar-derived gradient has a low confidence level. On the other hand, 39 Ar activities group close to a mean value of 22.5 dpm/kg FeNi and appear to be almost independent of the different meteoroid orbits. A comparison of measured 39 Ar activities in meteorites with those calculated for orbits obtained from fireball data shows that a gradient of 10%/Au or less is reconcilable with the experimental findings. The average gradient (E > 200 MeV) during the last 500 years was probably not much larger than that measured presently by the Pioneer 10 and 11, and Helios spacecrafts. (Auth.)

  13. Photoionization study of HgAr

    International Nuclear Information System (INIS)

    Linn, S.H.; Brom, J.M. Jr.; Tzeng, W.; Ng, C.Y.

    1985-01-01

    Photoionization efficiency data for HgAr + have been obtained in the region of 680--1240 A. The ionization energy of HgAr was determined to be 10.217 +- 0.012 eV. This value allows the calculation of the dissociation energy of HgAr + to be 0.228 +- 0.017 eV. The relative probabilities for the formation of HgAr + via the reactions Ar* x Hg or Hg* x Ar→ HgAr + +e - with Ar* and Hg* prepared in high Rydberg states in the energy range of 10.22--15.79 eV were estimated. Although the radii for the 3d and 5s Rydberg ortitals of Ar have similar values, the probabilities for the formation of HgAr + from Hg x Ar* with Ar* in the 5s[3/2] 0 1 and 5s'[1/2] 0 1 Rydberg states are substantially greater than those when the Ar* excited atoms are in the 3d[1/2] 0 1 , 3s[3/2] 0 1 , and 3d'[3/2] 0 1 Rydberg levels. The ratio for the cross sections for the formation of HgAr + from Hg x Ar* with Ar* formed in the 3d[1/2] 0 1 and 4d[1/2] 0 1 states, as well as that with Ar* prepared in the 5d[1/2] 0 1 and 6d[1/2] 0 1 states, were found to be consistent with the predictions of the previous impact parameter calculations

  14. Age measurements of potassium-bearing sulfide minerals by the 40Ar/39Ar technique

    International Nuclear Information System (INIS)

    Czamanske, G.K.; Lanphere, M.A.; Erd, R.C.; Blake, M.C. Jr.

    1978-01-01

    K-Ar ages have been determined for sulfide minerals for the first time. The occurrence of adequate amounts of potassium-bearing sulfides with ideal compositions K 3 Fe 10 S 14 (approximately 10 wt.% K) and KFe 2 S 3 (approximately 16 wt.% K) in samples from a mafic alkalic diatreme at Coyote Peak, California, prompted an attempt to date these materials. K 3 Fe 10 S 14 , a massive mineral with conchoidal fracture, gives an age of 29.4 +- 0.5 m.y. ( 40 Ar/ 39 Ar), indistinguishable from the 28.3 +- 0.4 m.y. ( 40 Ar/ 39 Ar) and 30.2 +- 1.0 m.y. (conventional K-Ar) ages obtained for associated phlogopite (8.7 wt.% K). KFe 2 S 3 , a bladed, fibrous sulfide, gives a younger age, 26.5 +- 0.5 m.y. ( 40 Ar/ 39 Ar), presumably owing to Ar loss. (Auth.)

  15. Ar-Ar dating techniques for terrestrial meteorite impacts

    Science.gov (United States)

    Kelley, S. P.

    2003-04-01

    The ages of the largest (>100 km) known impacts on Earth are now well characterised. However the ages of many intermediate sized craters (20-100 km) are still poorly known, often the only constraints are stratigraphic - the difference between the target rock age and the age of crater filling sediments. The largest impacts result in significant melt bodies which cool to form igneous rocks and can be dated using conventional radiometric techniques. Smaller impacts give rise to thin bands of melted rock or melt clasts intimately mixed with country rock clasts in breccia deposits, and present much more of a challenge to dating. The Ar-Ar dating technique can address a wide variety of complex and heterogeneous samples associated with meteorite impacts and obtain reasonable ages. Ar-Ar results will be presented from a series of terrestrial meteorite impact craters including Boltysh (65.17±0.64 Ma, Strangways (646±42 Ma), and St Martin (220±32 Ma) and a Late Triassic spherule bed, possibly representing distal deposits from Manicouagan (214±1 Ma) crater. Samples from the Boltysh and Strangways craters demonstrate the importance of rapid cooling upon the retention of old ages in glassy impact rocks. A Late Triassic spherule bed in SW England is cemented by both carbonate and K-feldspar cements allowing Ar-Ar dating of fine grained cement to place a mimimum age upon the age of the associated impact. An age of 214.7±2.5 Ma places the deposit with errors of the age of the Manicouagan impact, raising the possibility that it may represent a distal deposit (the deposit lay around 2000 km away from the site of the Manicouagan crater during the Late Triassic). Finally the limits of the technique will be demonstrated using an attempt to date melt rocks from the St Martin Crater in Canada.

  16. 0100101110101101.ORG / Tilman Baumgärtel

    Index Scriptorium Estoniae

    Baumgärtel, Tilman

    2006-01-01

    Veebilehekülje 0100101110101101.ORG taga asuvad itaallased ei soovi oma nimesid avaldada, rühmitus kutsub ennast zero one dot org (01.org). 9. 10. 1999 Pariisis tehtud intervjuu rühmituse liikmetega, keda huvitab kunstiteemaline diskussioon. Võrgukunstnikena tegid nad oma nime tuntuks võrgukunsti galerii "Hell.com" nn vargusega. Nad on oma leheküljele üles pannud Olja Ljalina galerii "art.teleportica" koopia jt. koopiaid. Tööst "Life-Sharing" (2001)

  17. ScattAR

    DEFF Research Database (Denmark)

    Baldwin, Alex Dempster; Serafin, Stefania; Erkut, Cumhur

    2017-01-01

    We present an augmented reality (AR) audio application where scattering delay networks efficiently generate and organize a reverberator, based on room geometry scanned by an AR device. The application allows for real-time processing and updating of reflection path geometry. It provides a proof...

  18. Ar-39/Ar-40 systematics of Allende inclusions

    International Nuclear Information System (INIS)

    Herzog, G.F.; Rutgers University, New Brunswick, NJ); Bence, A.E.

    1980-01-01

    A laser microprobe was used to measure the Ar isotopic contents of individual mineral grains in four neutron-irradiated Allende samples: two coarse-grained Ca-Al-rich inclusions, one fine-grained Ca-Al-rich inclusion, and one sample with matrix and miscellaneous chondrules. The following K-Ar ages (G.y.) were obtained after degassing low Ar retentive sites by preheating the samples for one hour at 675 C: matrix, 3.5 + or - 0.2 three miscellaneous chondrules, 4.4 + or - 0.1, 4.0 + or - 0.1, and 4.4 + or - 0.1 and the fine-grained inclusion, 4.5 + or - 0.2. The minerals in the coarse-grained Ca-Al-rich inclusions have ubiquitous chlorine, less than 10 ppm K and apparent ages ranging upwards from 4.6 G.y. to well over 10 G.y. Possible explanations for these apparent ages are atmospheric contamination, the decay of K-40 prior to the formation of the solar system, and the trapping of radiogenic Ar-40 lost by the matrix

  19. AR4VI: AR as an Accessibility Tool for People with Visual Impairments.

    Science.gov (United States)

    Coughlan, James M; Miele, Joshua

    2017-10-01

    Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness - an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a range of accessibility barriers. Rather than being restricted to use by people with visual impairments, AR4VI is a compelling universal design approach offering benefits for mainstream applications as well.

  20. Research use of the AIDA www.2aida.org diabetes software simulation program: a review--part 2. Generating simulated blood glucose data for prototype validation.

    Science.gov (United States)

    Lehmann, Eldon D

    2003-01-01

    The purpose of this review is to describe research applications of the AIDA diabetes software simulator. AIDA is a computer program that permits the interactive simulation of insulin and glucose profiles for teaching, demonstration, and self-learning purposes. Since March/April 1996 it has been made freely available on the Internet as a noncommercial contribution to continuing diabetes education. Up to May 2003 well over 320,000 visits have been logged at the main AIDA Website--www.2aida.org--and over 65,000 copies of the AIDA program have been downloaded free-of-charge. This review (the second of two parts) overviews research projects and ventures, undertaken for the most part by other research workers in the diabetes computing field, that have made use of the freeware AIDA program. As with Part 1 of the review (Diabetes Technol Ther 2003;5:425-438) relevant research work was identified in three main ways: (i) by personal (e-mail/written) communications from researchers, (ii) via the ISI Web of Science citation database to identify published articles which referred to AIDA-related papers, and (iii) via searches on the Internet. Also, in a number of cases research students who had sought advice about AIDA, and diabetes computing in general, provided copies of their research dissertations/theses upon the completion of their projects. Part 2 of this review highlights some more of the research projects that have made use of the AIDA diabetes simulation program to date. A wide variety of diabetes computing topics are addressed. These range from learning about parameter interactions using simulated blood glucose data, to considerations of dietary assessments, developing new diabetes models, and performance monitoring of closed-loop insulin delivery devices. Other topics include evaluation/validation research usage of such software, applying simulated blood glucose data for prototype training/validation, and other research uses of placing technical information on the Web

  1. 40Ar/39Ar age spectra from the KBS Tuff, Koobi Fora Formation

    International Nuclear Information System (INIS)

    McDougall, I.

    1981-01-01

    40 Ar/ 39 Ar age spectra on anorthoclase phenocrysts from three pumice clasts in the KBS Tuff yield nearly ideal flat patterns, providing good evidence that the samples have remained undisturbed since crystallization. The ages are concordant at 1.88 = 0.02 Myr, and confirm that the KBS Tuff, a key marker bed in the Koobi Fora Formation, northern Kenya, is now very well dated. These results resolve the conflict between earlier 40 Ar/ 39 Ar and conventional K-Ar dating measurements on the KBS Tuff. (author)

  2. 40Ar/39Ar age spectra from the KBS Tuff, Koobi Fora Formation.

    Science.gov (United States)

    McDougall, Ian

    1981-11-12

    40 Ar/ 39 Ar age spectra on anorthoclase phenocrysts from three pumice clasts in the KBS Tuff yield nearly ideal flat patterns, providing good evidence that the samples have remained undisturbed since crystallization. The ages are concordant at 1.88±0.02 Myr, and confirm that the KBS Tuff, a key marker bed in the Koobi Fora Formation, northern Kenya, is now very well dated. These results resolve the conflict between earlier 40 Ar/ 39 Ar and conventional K-Ar dating measurements on the KBS Tuff.

  3. MonitAR, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop MonitAR, an Augmented Reality (AR) system that provides procedure completion guidance to astronauts. MonitAR will replace guidance from mission...

  4. The 40Ar/39Ar and K/Ar dating of lavas from the Hilo 1-km core hole, Hawaii Scientific Drilling Project

    Science.gov (United States)

    Sharp, W.D.; Turrin, B.D.; Renne, P.R.; Lanphere, M.A.

    1996-01-01

    Mauna Kea lava flows cored in the HilIo hole range in age from <200 ka to about 400 ka based on 40Ar/39Ar incremental heating and K-Ar analyses of 16 groundmass samples and one coexisting plagioclase. The lavas, all subaerially deposited, include a lower section consisting only of tholeiitic basalts and an upper section of interbedded alkalic, transitional tholeiitic, and tholeiitic basalts. The lower section has yielded predominantly complex, discordant 40Ar/39Ar age spectra that result from mobility of 40Ar and perhaps K, the presence of excess 40Ar, and redistribution of 39Ar by recoil. Comparison of K-Ar ages with 40Ar/39Ar integrated ages indicates that some of these samples have also lost 39Ar. Nevertheless, two plateau ages of 391 ?? 40 and 400 ?? 26 ka from deep in the hole, combined with data from the upper section, show that the tholeiitic section accumulated at an average rate of about 7 to 8 m/kyr and has an mean recurrence interval of 0.5 kyr/flow unit. Samples from the upper section yield relatively precise 40Ar/39Ar plateau and isotope correlation ages of 326 ?? 23, 241 ?? 5, 232 ?? 4, and 199 ?? 9 ka for depths of -415.7 m to -299.2 m. Within their uncertainty, these ages define a linear relationship with depth, with an average accumulation rate of 0.9 m/kyr and an average recurrence interval of 4.8 kyr/flow unit. The top of the Mauna Kea sequence at -280 m must be older than the plateau age of 132 ?? 32 ka, obtained for the basal Mauna Loa flow in the corehole. The upward decrease in lava accumulation rate is a consequence of the decreasing magma supply available to Mauna Kea as it rode the Pacific plate away from its magma source, the Hawaiian mantle plume. The age-depth relation in the core hole may be used to test and refine models that relate the growth of Mauna Kea to the thermal and compositional structure of the mantle plume.

  5. Pharmacokinetics and pharmacokinetic-dynamic relationship between rapacuronium (Org 9487) and its 3-desacetyl metabolite (Org 9488)

    NARCIS (Netherlands)

    Schiere, S; Proost, Hans; Schuringa, M; Wierda, J.MKH

    Rapacuronium (Org 9487) is a rapid-onset and short- to intermediate-acting muscle relaxant. Its 3-desacetyl metabolite, Org 9488, also exerts neuromuscular-blocking activity that. may became apparent after prolonged maintenance of relaxation with rapacuronium. In this study, the pharmacokinetic

  6. Internet FAQ Archives - Online Education - faqs.org

    Science.gov (United States)

    faqs.org Internet FAQ Archives - Online Education faqs.org faqs.org - Internet FAQ Archives Internet FAQ Archives Online Education Internet RFC Index Usenet FAQ Index Other FAQs Documents Tools IFC Rated FAQs Internet RFC/STD/FYI/BCP Archives The Internet RFC series of documents is also available from

  7. AR4VI: AR as an Accessibility Tool for People with Visual Impairments

    OpenAIRE

    Coughlan, James M.; Miele, Joshua

    2017-01-01

    Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness – an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a r...

  8. Reevaluation of the Solar Wind 36Ar/38Ar Ratio

    Science.gov (United States)

    Becker, R. H.; Schlutter, D. J.; Rider, P. E.; Pepin, R. O.

    1996-03-01

    The isotopic composition of solar wind (SW) argon is an important parameter in the modeling of the evolution of the terrestrial planet atmospheres. Anders and Grevesse assumed a 36Ar/38Ar ratio for SW of 5.31, essentially equal to that of air. Considerable evidence has since developed which indicates that this ratio is too low. Benkert et al. have reported their best estimate for the recent SW as 5.48 +/- 0.05, determined from measurements of lunar soil 71501. Based on Ar data obtained from surface oxidation of a metal separate from the Weston meteorite and from an uncontrolled etch of lunar sample 67701, reported by our group previously, we consider even this value to be too low. Since values of 5.75 to 5.85 were reported by Black for initial low temperature (fairly high SW 36Ar/38Ar ratio (in the range of ~5.6 to ~5.7), we decided to analyze Kapoeta for its light solar wind gases using the acid-etching techniques developed in our laboratory based on the CSSE procedure of Benkert et al.

  9. 40Ar/39Ar laser-probe dating of diamond inclusions from the Premier kimberlite

    International Nuclear Information System (INIS)

    Phillips, D.; Onstott, T.C.; Harris, J.W.; Strathclyde Univ., Glasgow

    1989-01-01

    Inclusions encapsulated by diamonds at the time of their formation provide a means for determining diamond crystallization ages and the chemistry of the surrounding upper mantle at that time. Sm-Nd studies of peridotitic inclusions, from Cretaceous-age kimberlites in southern Africa, suggest that the diamonds formed 3.3 Gyr ago. By contrast, eclogite-suite inclusions generally yield younger ages, sometimes approaching the time of kimberlite eruption. Here we report the results of 40 Ar/ 39 Ar laser-probe analyses of individual eclogitic clinopyroxene inclusions from Premier diamonds, which yield a mean age of 1,198±14 Myr. This age agrees well with Sm-Nd and 40 Ar/ 39 Ar analyses on similar Premier inclusions, and is indistinguishable from the inferred time of emplacement of the host kimberlite (1,150-1,230 Myr), which implies that diamond formation was essentially synchronous with kimberlite generation. The extrapolated non-radiogenic 40 Ar/ 36 Ar ratio of 334±102 is similar to the present-day atmospheric composition. This value is inconsistent with Sr and Nd isotopic signatures from Premier eclogite inclusions, which suggest a depleted mantle source ( 40 Ar/ 36 Ar>20,000). Pre-entrapment equilibration of the inclusions with an 36 Ar-rich fluid is the most probable explanation for the low non-radiogenic ( 40 Ar/ 36 Ar) composition. (author)

  10. Ars disyecta Ars disyecta

    Directory of Open Access Journals (Sweden)

    Alejandra Castillo

    2012-07-01

    Full Text Available Bajo la nominación Ars Disyecta se busca exponer el vínculo entre artes visuales, feminismo y metamorfosis. Las prácticas artísticas feministas aquí presentadas se proponen perturbar el espacio metafórico heredado de la diferencia sexual (pensemos, por ejemplo, en las palabras engendramiento, matriz, vida, compenetración o invaginamiento. En este sentido, la nominación Ars disyecta pone en escena un conjunto de prácticas e intervenciones que intentan interrumpir la matriz de la diferencia, desestabilizando lo femenino desde aquellas figuras que se resisten a la lógica de la totalidad y de un tiempo propio. Buscando seguir la huella de un arte disyecto es que interrogaré en este ensayo aquellas autorías feministas que en el arte contemporáneo trafican con las huellas del contagio, la mutación y la alteridad.This article aims to present the relation between visual arts, feminism I and metamorphosis. The feminist artistic practices portrayed in this article attempt to question categories inherited from the metaphor of sexual difference such as engendering, matrix and life. From this perspective, Ars disyecta will establish a set of artistic practices and interventions that intend to interrupt the proper idea of «feminine difference». Following this line of argument, I will discuss in this article a few contemporary feminist works of art that could be defined by words such as contagious, mutation and otherness.

  11. 40Ar-39Ar method for age estimation: principles, technique and application in orogenic regions

    International Nuclear Information System (INIS)

    Dalmejer, R.

    1984-01-01

    A variety of the K-Ar method for age estimation by 40 Ar/ 39 Ar recently developed is described. This method doesn't require direct analysis of potassium, its content is calculated as a function of 39 Ar, which is formed from 39 K under neutron activation. Errors resulted from interactions between potassium and calcium nuclei with neutrons are considered. The attention is paid to the technique of gradual heating, used in 40 Ar- 39 Ar method, and of obtaining age spectrum. Aplicabilities of isochronous diagram is discussed for the case of presence of excessive argon in a sample. Examples of 40 Ar- 39 Ar method application for dating events in orogenic regions are presented

  12. Evidence of interatomic Coulombic decay in ArKr after Ar 2p Auger decay

    International Nuclear Information System (INIS)

    Morishita, Y; Saito, N; Suzuki, I H; Fukuzawa, H; Liu, X-J; Sakai, K; Pruemper, G; Ueda, K; Iwayama, H; Nagaya, K; Yao, M; Kreidi, K; Schoeffler, M; Jahnke, T; Schoessler, S; Doerner, R; Weber, T; Harries, J; Tamenori, Y

    2008-01-01

    We have identified interatomic Coulombic decay (ICD) processes in the ArKr dimer following Ar 2p Auger decay, using momentum-resolved electron-ion-ion coincidence spectroscopy and simultaneously determining the kinetic energy of the ICD electron and the KER between Ar 2+ and Kr + . We find that the spin-conserved ICD processes in which Ar 2+ (3p -3 3d) 1 P and 3 P decay to Ar 2+ (3p -2 ) 1 D and 3 P, respectively, ionizing the Kr atom, are significantly stronger than the spin-flip ICD processes in which Ar 2+ (3p -3 3d) 1 P and 3 P decay to Ar 2+ (3p -2 ) 3 P and 1 D, respectively

  13. Feldspar 40Ar/39Ar dating of ICDP PALEOVAN cores

    Science.gov (United States)

    Engelhardt, Jonathan Franz; Sudo, Masafumi; Stockhecke, Mona; Oberhänsli, Roland

    2017-11-01

    Volcaniclastic fall deposits in ICDP drilling cores from Lake Van, Turkey, contain sodium-rich sanidine and calcium-rich anorthoclase, which both comprise a variety of textural zoning and inclusions. An age model records the lake's history and is based on climate-stratigraphic correlations, tephrostratigraphy, paleomagnetics, and earlier 40Ar/39Ar analyses (Stockhecke et al., 2014b). Results from total fusion and stepwise heating 40Ar/39Ar analyses presented in this study allow for the comparison of radiometric constraints from texturally diversified feldspar and the multi-proxy lacustrine age model and vice versa. This study has investigated several grain-size fractions of feldspar from 13 volcaniclastic units. The feldspars show textural features that are visible in cathodoluminescence (CL) or back-scattered electron (BSE) images and can be subdivided into three dominant zoning-types: (1) compositional zoning, (2) round pseudo-oscillatory zoning and (3) resorbed and patchy zoning (Ginibre et al., 2004). Round pseudo-oscillatory zoning records a sensitive alternation of Fe and Ca that also reflects resorption processes. This is only visible in CL images. Compositional zoning reflects anticorrelated anorthite and orthoclase contents and is visible in BSE. Eleven inverse isochron ages from total fusion and three from stepwise heating analyses fit the age model. Four experiments resulted in older inverse isochron ages that do not concur with the model within 2σ uncertainties and that deviate from 1 ka to 17 ka minimum. C- and R-type zoning are interpreted as representing growth in magma chamber cupolas, as wall mushes, or in narrow conduits. Persistent compositions of PO-type crystals and abundant surfaces recording dissolution features correspond to formation within a magma chamber. C-type zoning and R-type zoning have revealed an irregular incorporation of melt and fluid inclusions. These two types of zoning in feldspar are interpreted as preferentially

  14. Photodissociation dynamics of Ar2(+) and Ar3(+) excited by 527 nm photons.

    Science.gov (United States)

    Lepère, V; Picard, Y J; Barat, M; Fayeton, J A; Lucas, B; Béroff, K

    2009-05-21

    The photofragmentation dynamics of Ar(2)(+) and Ar(3)(+) clusters has been investigated at a 527 nm wavelength (2.35 eV) using a setup that allows simultaneous detection of the ionic and neutral fragments in a coincidence experiment. Measurement of positions and times of flight enables in principle a complete description of the fragmentation dynamics. The photofragmentation dynamics of Ar(3)(+) clusters is similar to that of Ar(2)(+) with, in addition, the ejection of a third fragment that can be neutral or ionized via a resonant electron capture. This is attributed to the triangular geometry of the Ar(3)(+) ion.

  15. The effects of acid treatment and sample preparation on 40Ar/39Ar ages

    Science.gov (United States)

    Morgan, L. E.; Davidheiser, B.; Kuiper, K.; Wijbrans, J. R.

    2011-12-01

    Practitioners of K-Ar and 40Ar/39Ar geochronology regularly use dilute acids (typically 5-10% hydrofluoric acid (HF)) to clean mineral grains prior to irradiation (in the case of 40Ar/39Ar), and analysis (e.g. Evernden and Curtis, 1965; Dalrymple, 1967). This treatment has been shown to reduce contamination from atmospheric Ar, which consists largely of 40Ar and thus must be differentiated from radiogenic 40Ar* (Evernden and Curtis, 1965). Acid treatments can also remove fine grained material attached to mineral grains, such as glass shards or devitrified glass, which can affect analyses and is difficult to remove by other means (Evernden and Curtis, 1965). Such treatments were originally examined for their efficacy in reducing atmospheric argon contamination (Dalrymple, 1967) but were not assessed for the possibility of leaching Ar* or K differentially, which would affect both K-Ar and 40Ar/39Ar ages. Indeed, Evernden and Curtis (1965) state that they are simply removing the "outer portions of the crystals" and apparently do not account for the potential for leaching of 40Ar* or K from the mass of their host mineral. Moreover, the capabilities of the K-Ar system in the 1960s was limited to a precision of ca. 3-4% on samples of 1-3 Ma (Cox and Dalrymple, 1967). Effects of smaller magnitude could not have been detected at the time. As the developments of the 40Ar/39Ar system and modern mass spectrometer technology have allowed for precision to approach 0.1%, the potential effects of acid treatment during sample preparation warrant revisiting. Additionally, the use of Calgon for sample disintegration has not previously been quantitatively assessed but is used extensively in some laboratories. Here we present a series of experiments from co-irradiated Fish Canyon sanidine (FCs) and Mes-4 (Kuiper et al., 2008). FCs is used as the mineral standard following standard procedures. Mes-4 splits were treated with H2O (10 minutes, ultrasonic), Calgon (10%, overnight at 50

  16. Marine Science and Education in one Word: "planeetzee.org"

    Science.gov (United States)

    Seys, J.; Copejans, E.; Ameije, K.

    2009-04-01

    It is a major challenge to bring science and technology to the public at large and more particular to young people. This is even more true for marine sciences, due to the very nature of the study field and the fact that the underwater world is difficult to experience and communicate. Therefore it is not surprising that in Europe there are only few examples of marine educational projects that try to go beyond the ‘observe and describe' approach. In 2004 SHE Consultancy, the Flanders Marine Institute VLIZ and DAB Vloot developed a first Belgian e-learning programme dedicated to oceans and seas, with the support of the Flemish government ("Action plan Science Communication"). This programme ‘Expedition Zeeleeuw' (www.expeditiezeeleeuw.be), ran from 2005 till 2007 and challenged some 3000 Flemish students of 16-18 years old all over Flanders to find creative solutions for 10 major marine issues at the Belgian coast. The class that could convince the jury to have discovered the most creative and intelligent solutions, wan a one-week scientific expedition at sea on board the vessel Zeeleeuw. As a successor to ‘Expedition Zeeleeuw', a new e-learning project on marine science was developed in 2007: ‘Planeet Zee' i.e. ‘Planet Ocean' (www.planeetzee.org; info via info@planeetzee.org + demo-site in English available at www.planetocean.eu). The new marine and coastal e-learning project is presented as a virtual sailing trip on the Atlantic Ocean. It follows the adventures of two youngsters "borrowing" the yacht of their father and getting into trouble on the open ocean. On this journey they face 21 problems (eg. out of food, drinking water or fuel, fear for whales, Bermuda triangle, tsunami's etc… ), each of them introduced by a short movie clip. When they realize they can not solve the problem, they ask for radio help and - what a surprise! - get interesting answers from the Zeeleeuw research vessel and its 21 marine scientists on board, that appears to be in the

  17. 40Ar/36Ar in MORB glasses: Constraints on atmosphere and mantle evolution

    International Nuclear Information System (INIS)

    Sarda, P.; Staudacher, T.; Allegre, C.J.; Paris-7 Univ., 75

    1985-01-01

    Argon isotopic composition measurements of MORB glassy samples from the Pacific, Atlantic and Indian Oceans are performed. There is a very large scatter in the 40 Ar/ 36 Ar ratio, from 980 up to 24,400 for bulk rock analyses, which is mainly due to atmospheric contamination: Using the stepwise heating technique, very high ratios are obtained, from 15,000 up to 25,250 which is the highest 40 Ar/ 36 Ar ratio ever measured in MORB. We establish a negative correlation between the highest 40 Ar/ 36 Ar results from stepwise heating and 87 Sr/ 86 Sr ratios, which is perfectly consistent with a two-layered mantle structure. From both 40 Ar and 129 Xe MORB systematics a model is proposed for the kinetics of degassing: a very early and extensive burst, with a time constant of approx.= 4 My, is followed by a slower process of present day type, with a time constant of approx.= 0.5 Gy. The mean age of the atmosphere is so determined to be around 4.4 Gy. (orig./WB)

  18. Build a WWW Homepage for Your School!

    Science.gov (United States)

    Chrobak, Kimberly

    1995-01-01

    Discusses the use of World Wide Web (WWW) Homepage for school information. Topics include school sites; installation of a WWW browser; file tags; sites for beginner's guides to the language (HTML); two Usenet discussion groups; and a sample lesson plan including objective, procedure, and evaluation. (AEF)

  19. Legacy K/Ar and 40Ar/39Ar geochronologic data from the Alaska-Aleutian Range batholith of south-central Alaska

    Science.gov (United States)

    Koeneman, Lisa L.; Wilson, Frederic H.

    2018-04-06

    Sample descriptions and analytical data for more than 200 K/Ar and 40Ar/39Ar analyses from rocks of the Alaska-Aleutian Range batholith of south-central Alaska are reported here. Samples were collected over a period of 20 years by Bruce R. Reed and Marvin A. Lanphere (both U.S. Geological Survey) as part of their studies of the batholith.

  20. On the doubly ionized states of Ar2 and their intra- and interatomic decay to Ar23+

    International Nuclear Information System (INIS)

    Stoychev, Spas D.; Kuleff, Alexander I.; Tarantelli, Francesco; Cederbaum, Lorenz S.

    2008-01-01

    Potential energy curves of the Auger state Ar + (2p -1 )-Ar, the different one- and two-site dicationic states Ar 2 ++ (with energies in the range of 32-77 eV), and the lowest two-site tricationic states Ar ++ -Ar + (with energies in the range of 64-76 eV) computed using elaborated ab initio methods are reported. The accessible relaxation channels of the electronic states of Ar ++ -Ar populated by Auger decay are studied. In particular, we study in detail the interatomic Coulombic decay following the population of one-site satellite states of Ar ++ (3s -1 3p -1 )-Ar recently observed experimentally. Other relaxation pathways of Ar ++ -Ar, including radiative charge transfer, nuclear dynamics through curve crossing, and intra-atomic decay processes are also investigated

  1. 40Ar-39Ar age determinations on the Owyhee basalt of the Columbia plateau

    International Nuclear Information System (INIS)

    Bottomley, R.J.; York, D.

    1976-01-01

    40 Ar/ 39 Ar step-heating analyses have been performed on 11 samples of basalt from sites near Owyhee Reservoir of southeastern Oregon, U.S.A. These rocks were extruded during the great flood basalt episode of the Pacific Northwest. The whole-rock points are highly correlated on a plot of 40 Ar/ 36 Ar versus 39 Ar/ 36 Ar, corresponding to a common age of the samples of 14.3+-0.3 m.y. Inspite of this, individual 'plateau' plots of the age versus fraction of 39 Ar released do not give good plateaux. These age spectra exhibit to varying degrees a common structure in which lower age values are found at higher temperatures. This pattern may result from a closed-system redistribution of the argon isotopes. The usefulness of grinding the basalts in removing a loosely held atmospheric argon component is confirmed. (Auth.)

  2. 40Ar/39Ar age and thermal history of the Kirin chondrite

    International Nuclear Information System (INIS)

    Wang, S.; McDougall, I.; Tetley, N.; Harrison, T.M.

    1980-01-01

    The Kirin meteorite, a large (> 2800 kg) H5 chondrite, fell in Kirin Province, China in 1976. A sample from each of the two largest fragments (K-1. K-2) yield 40 Ar/ 39 Ar total fusion ages of 3.63 +- 0.02 b.y. and 2.78 +- 0.02 b.y. respectively. 40 Ar/ 40 Ar age spectra show typical diffusional argon loss profiles. Maximum apparent ages of 4.36 b.y. (K-1) and approx. 4.0 b.y. (K-2) are interpreted as possible minimum estimates for the age of crystallization of the parent body. (orig./ME)

  3. The effects of retrograde reactions and of diffusion on 39Ar-40Ar ages of micas

    DEFF Research Database (Denmark)

    Allaz, Julien; Engi, Martin; Berger, Alfons

    2011-01-01

    Effects of metamorphic reactions occurring during decompression were explored to understand their influence on 39Ar-40Ar ages of micas. Monometamorphic metasediments from the Lepontine Alps (Switzerland) were studied. Collected samples reached lower amphibolite facies during the Barrovian....... XRD-data indicated that some mineral separates prepared for Ar-Ar stepwise heating analysis were monomineralic, whereas others were composed of two white micas (muscovite with paragonite or margarite), or biotite and chlorite. In monomineralic samples 37Ar/39Ar and 38Ar/39Ar (proportional to Ca....../K and Cl/K ratios) did not change and the resulting ages can be interpreted unambiguously. In mineral separates containing two white micas, Ca/K and Cl/K ratios were variable, reflecting non-simultaneous laboratory degassing of the two heterochemical Ar-reservoirs. These ratios were used to identify each...

  4. Geochronology and thermochronology by the sup 40 Ar/ sup 39 Ar method

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, I. (Australian National Univ., Canberra (Australia)); Harrison, T.M. (State Univ. of New York, Albany, NY (USA))

    1988-01-01

    This work is a response to the authors' belief that there is a need for a monograph on {sup 40}Ar/{sup 39}Ar dating to provide concise knowledge concerning the application of this method to geological studies. They aim to provide a reasonably comprehensive but by no means exhaustive coverage of the principles and practices of {sup 40}Ar/{sup 39}Ar dating, with emphasis on interpretation of results. In attempting to provide an overview of the current state of knowledge, they commonly cite examples from the available literature. They draw rather heavily upon their own work, because they feel comfortable with their own examples. (author).

  5. Vínculos que potencian: la relación entre el análisis de redes sociales (ARS y la Etnografía

    Directory of Open Access Journals (Sweden)

    Lorena Pasarin

    2014-08-01

    Full Text Available http://dx.doi.org/10.5007/1518-2924.2014v19n40p145 En este artículo se aborda la utilidad de las herramientas metodológicas de Análisis de Redes Sociales (ARS y su aplicación en el campo de la etnografía. También se reflexiona sobre los aportes de la etnografía al ARS. Se analiza una selección de estudios etnográficos clásicos y actuales, que permiten ejemplificar y analizar un modo en que es posible resolver los problemas empíricos entre ambos campos teóricos y metodológicos. El manejo de los instrumentos metodológicos permite complementar y beneficiar ambas perspectivas. Se expondrá cómo algunas exploraciones en el área de la Etnografía se han desarrollado a partir de los aportes del ARS.

  6. National Heart, Lung, and Blood Institute National Asthma Education and Prevention Program

    Science.gov (United States)

    ... www.aanma.org American Academy of Allergy, Asthma & Immunology 414–272–6071 www.aaaai.org American Academy ... www.aasa.org American College of Allergy, Asthma & Immunology 847–427–1200 www.acaai.org American Lung ...

  7. A brief overview of the Chemistry-Aerosol Mediterranean Experiment (ChArMEx) database and campaign operation centre (ChOC)

    Science.gov (United States)

    Ferré, Hélène; Dulac, François; Belmahfoud, Nizar; Brissebrat, Guillaume; Cloché, Sophie; Descloitres, Jacques; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Ramage, Karim; Vermeulen, Anne

    2016-04-01

    Initiated in 2010 in the framework of the multidisciplinary research programme MISTRALS (Mediterranean Integrated Studies at Regional and Local Scales; http:www.mistrals-home.org), the Chemistry-Aerosol Mediterranean Experiment (ChArMEx, http://charmex.lsce.ipsl.fr/) aims at federating the scientific community for an updated assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The project combines mid- and long-term monitoring, intensive field campaigns, use of satellite data, and modelling studies. In this presentation we provide an overview of the campaign operation centre (http://choc.sedoo.fr/) and project database (http://mistrals.sedoo.fr/ChArMEx), at the end of the first experimental phase of the project that included a series of large campaigns based on airborne means (including balloons and various aircraft) and a network of surface stations. Those campaigns were performed mainly in the western Mediterranean basin in the summer of 2012, 2013 and 2014 with the help of the ChArMEx Operation Centre (ChOC), an open web site that has the objective to gather and display daily quick-looks from model forecasts and near-real time in situ and remote sensing observations of physical and chemical weather conditions relevant for the everyday campaign operation decisions. The ChOC is also useful for post campaign analyses and can be completed with a number of quick-looks of campaign results obtained later in order to offer an easy access to, and comprehensive view of all available data during the campaign period. The items included are selected according to the objectives and location of the given campaigns. The second experimental phase of ChArMEx from 2015 on is more focused on the eastern basin. In addition, the project operation centre is planned to be adapted for a joint MERMEX-ChArMEx oceanographic cruise (PEACETIME) for a study at

  8. Taking the first step is to move half way

    Directory of Open Access Journals (Sweden)

    Loza-Murguia Manuel G.

    2010-10-01

    Full Text Available Journal of the Selva Andina Research Society (JSARS, is an official Journal of the Society for Researching Selva Andina (Selva Andina Research Society “SARS” of the Department of Education and Research in Biochemistry & Microbiology (in Spanish DEI & BM, the Peasant Academic Unit from Carmen Pampa of the Bolivian Catholic University “San Pablo”, from the year 2009, is being part of the net SciELO Scientific Electronic Library Online in developing. The net of electronic publication of journals by internet, response to the requirements of the countries from Latina America and Caribbean, as a support to the scientific communication, providing visibility and access to scientific literature, its respects the common methodology in the preparation, storage, dissemination and evaluation of scientific articles in electronic format. To date, eight Bolivian journals are being part of the SciELO Network - Bolivia: http:www.scielo.org. Participating countries such as Argentina, Brazil, Chile, Colombia, Cuba, Spain, Portugal and Venezuela, besides SciELO “SciELO Public Health and Social Sciences”; countries that are developing as Bolivia, Mexico, Paraguay, Costa Rica, Peru, Uruguay and South Africa . SciELO - Bolivia was made possible by the participation of different institutions like the Universidad Mayor de San Andrés, the Strategic Research Program in Bolivia, the Bolivian Catholic University, the Bolivian Association for Biomedical Journal Editors and the Vice Ministry of Science and Technology the support of the Pan American Health Organization (PAHO Representation Bolivia. To be part of the this project Journal of the Selva Andina Research Society SciELO-Bolivia, and meet the requirements in the criteria, policies and procedures for application, acceptance and permanence of scientific journals in the SciELO collection - Bolivia, achieving desired by the Chairman of the Board of the Supreme Council on Science and Biotechnology Society

  9. 40Ar/39Ar and K-Ar age constraints on the timing of regional deformation, south coast of New South Wales, Lachlan Fold Belt: problems and implications

    International Nuclear Information System (INIS)

    Fergusson, C.L.; Phillips, D.

    2001-01-01

    Four slate samples from subduction complex rocks exposed on the south coast of New South Wales, south of Batemans Bay, were analysed by K-Ar and 40 Ar/ 39 Ar step-heating methods, One sample contains relatively abundant detrital muscovite flakes that are locally oblique to the regional cleavage in the rock, whereas the remaining samples appear to contain sparse detrital muscovite. Separates of detrital muscovite yielded plateau ages of 505 + 3 Ma and 513 + 3 Ma indicating that inheritance has not been eliminated by metamorphism and recrystallisation. Step-heating analyses of whole-rock chips from all four slate samples produced discordant apparent age spectra with 'saddle shapes' following young apparent ages at the lowest temperature increments. Elevated apparent ages associated with the highest temperature steps are attributed to the presence of variable quantities of detrital muscovite ( 40 Ar/ 39 Ar integrated ages of ca 455Ma, which are some 15-30 million years older than K-Ar ages for the same samples. These discrepancies suggest that the slates have also been affected by recoil loss/redistribution of 39 Ar, Ieading to anomalously old 40 Ar/ 39 Ar ages. Two other samples, from slaty tectonic melange and intensely cleaved slate, yielded average 40 Ar/ 39 Ar integrated ages of ca 424Ma, which are closer to associated mean K-Ar ages of 423 + 4Ma and 409 + 16Ma, respectively. Taking into account the potential influences of recoil loss/redistribution of 39 Ar and inheritance, the results from the latter samples suggest a maximum age of ca 440 Ma for deformation/metamorphism. The current results indicate that recoil and inheritance problems may also have affected whole-rock 40 Ar/ 39 Ar data reported from other regions of the Lachlan Fold Belt. Therefore, until these effects are adequately quantified, models for the evolution of the Lachlan Fold Belt, that are based on such whole-rock 40 Ar/ 39 Ar data, should be treated with caution. Copyright (2001) Geological

  10. Alignment and orientation of Ar+ in He+-Ar collisions

    International Nuclear Information System (INIS)

    Moudry, B.W.; Yenen, O.; Jaecks, D.H.

    1994-01-01

    We have measured the alignment and orientation parameters of the 2 F 7/2 0 and 2 F 5/2 0 states of Ar + formed in the two-electron process; He + +Ar→He(1s 2 )+Ar + (3p 4 4p'). These have been measured at a collision energy of 0.25 keV/amu and for scattering angles ranging from 0.94 to 3.75 . First, by comparing the orientation prameter for the Ar + [(3p 4 [ 1 D]4p' 2 F 7/2 0 ] and the Ar + [(3p 4 [ 1 D]4p' 2 F 5/2 0 ] states, we have experimentally determined the importance of the spin-dependent interactions for the present collision system, by testing the Percival-Seaton hypothesis of spin independence. If the Percival-Seaton hypothesis holds for this system, the orientation parameter should be J-independent. Secondly, the magnitude of the orientation prameter can be interpreted as resulting from the collective circulation of the unexcited 3p 4 electrons and the excited 4p electron. The direction of this collective circulation is compared to the propensity rule for colliding di-atom systems. (orig.)

  11. Trastornos mentales y del comportamiento orgánico

    Directory of Open Access Journals (Sweden)

    Roberto Anselmo Ramos Valverde

    2014-11-01

    Full Text Available La personalidad es plurideterminada, integrada por factores biológicos, psicológicos y socioculturales en igual jerarquía funcional y concatenación dialéctica, concepción necesaria para comprender el origen y formación de los procesos psicológicos. (1 En el Tercer Glosario Cubano de Psiquiatría (GC-3 se define como trastorno orgánico a los síndromes psiquiátricos, cuyas manifestaciones actuales fundamentales son la consecuencia directa de una alteración anatomofisiológica conocida del encéfalo, que implica una merma intrínseca de su capacidad para servir de sostén a una actividad mental normal, hecho éste que lo diferencia de aquellas entidades, en que la armonía funcional del cerebro se ve alterada por una sobrecarga de estrés o un aprendizaje anormal, que bloquea las capacidades fundamentales del órgano gestor del psiquismo sin destruirlas. (2, 3 Se entiende por trastornos mentales y del comportamiento orgánicos al conjunto de síntomas o comportamientos identificables en la práctica clínica, que surgen como consecuencia de un daño tisular asentado en el cerebro o fuera de él, que afecta la fisiología del Sistema Nervioso Central (SNC y, con ella, los mecanismos de reflexión de la realidad. (3 Definir el concepto de trastornos mentales y del comportamiento orgánico y crear una nueva clasificación, teniendo en cuenta la gravedad de los síntomas de utilidad en la formación del médico general y como soporte bibliográfico para el residente de Psiquiatría, constituyó la motivación fundamental para la realización de este editorial. (3 Trastornos mentales y del comportamiento orgánico menores constituyen un conjunto de entidades nosológicas, cuya sintomatología causa malestar y afecta la adaptación creadora del sujeto al medio, teniendo en cuenta su carácter persistente e irreversible. En muchos casos, no provocan distorsión grave de la realidad objetiva, pueden ser orgánicos, propiamente dicho, si la lesi

  12. NASA Lunar Impact Monitoring

    Science.gov (United States)

    Suggs, Robert M.; Moser, D. E.

    2015-01-01

    The MSFC lunar impact monitoring program began in 2006 in support of environment definition for the Constellation (return to Moon) program. Work continued by the Meteoroid Environment Office after Constellation cancellation. Over 330 impacts have been recorded. A paper published in Icarus reported on the first 5 years of observations and 126 calibrated flashes. Icarus: http://www.sciencedirect.com/science/article/pii/S0019103514002243; ArXiv: http://arxiv.org/abs/1404.6458 A NASA Technical Memorandum on flash locations is in press

  13. 3 to 15 keV Ar+ induced Auger electron emission from Si and Ar

    International Nuclear Information System (INIS)

    Kempf, J.; Kaus, G.

    1977-01-01

    Ar + induced Auger electrons from Si and Ar were investigated at bombardment energies between 3-15 keV and target currents of a few μA. The Auger electron yields were compared with secondary ion yields of Si and Ar by simultaneous SIMS-AES measurements. In the ion induced Auger spectra of Si five Auger peaks and in the Ar spectra three Auger peaks were observed. The ion induced Auger electron yield of Si and Ar were found to be strongly dependent upon the primary ion energy. 'Bulk like' and 'atomic like' Auger transitions of ion induced Auger electrons of Si were observed. (orig.) [de

  14. Androgen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells.

    Directory of Open Access Journals (Sweden)

    Young-Chae Kim

    Full Text Available The androgen receptor (AR mediates the developmental, physiologic, and pathologic effects of androgens including 5α-dihydrotestosterone (DHT. However, the mechanisms whereby AR regulates growth suppression and differentiation of luminal epithelial cells in the prostate gland and proliferation of malignant versions of these cells are not well understood, though they are central to prostate development, homeostasis, and neoplasia. Here, we identify androgen-responsive genes that restrain cell cycle progression and proliferation of human prostate epithelial cell lines (HPr-1AR and PC3-Lenti-AR, and we investigate the mechanisms through which AR regulates their expression. DHT inhibited proliferation of HPr-1AR and PC3-Lenti-AR, and cell cycle analysis revealed a prolonged G1 interval. In the cell cycle, the G1/S-phase transition is initiated by the activity of cyclin D and cyclin-dependent kinase (CDK complexes, which relieve growth suppression. In HPr-1AR, cyclin D1/2 and CDK4/6 mRNAs were androgen-repressed, whereas CDK inhibitor, CDKN1A, mRNA was androgen-induced. The regulation of these transcripts was AR-dependent, and involved multiple mechanisms. Similar AR-mediated down-regulation of CDK4/6 mRNAs and up-regulation of CDKN1A mRNA occurred in PC3-Lenti-AR. Further, CDK4/6 overexpression suppressed DHT-inhibited cell cycle progression and proliferation of HPr-1AR and PC3-Lenti-AR, whereas CDKN1A overexpression induced cell cycle arrest. We therefore propose that AR-mediated growth suppression of HPr-1AR involves cyclin D1 mRNA decay, transcriptional repression of cyclin D2 and CDK4/6, and transcriptional activation of CDKN1A, which serve to decrease CDK4/6 activity. AR-mediated inhibition of PC3-Lenti-AR proliferation occurs through a similar mechanism, albeit without down-regulation of cyclin D. Our findings provide insight into AR-mediated regulation of prostate epithelial cell proliferation.

  15. A user-friendly workflow for analysis of Illumina gene expression bead array data available at the arrayanalysis.org portal.

    Science.gov (United States)

    Eijssen, Lars M T; Goelela, Varshna S; Kelder, Thomas; Adriaens, Michiel E; Evelo, Chris T; Radonjic, Marijana

    2015-06-30

    Illumina whole-genome expression bead arrays are a widely used platform for transcriptomics. Most of the tools available for the analysis of the resulting data are not easily applicable by less experienced users. ArrayAnalysis.org provides researchers with an easy-to-use and comprehensive interface to the functionality of R and Bioconductor packages for microarray data analysis. As a modular open source project, it allows developers to contribute modules that provide support for additional types of data or extend workflows. To enable data analysis of Illumina bead arrays for a broad user community, we have developed a module for ArrayAnalysis.org that provides a free and user-friendly web interface for quality control and pre-processing for these arrays. This module can be used together with existing modules for statistical and pathway analysis to provide a full workflow for Illumina gene expression data analysis. The module accepts data exported from Illumina's GenomeStudio, and provides the user with quality control plots and normalized data. The outputs are directly linked to the existing statistics module of ArrayAnalysis.org, but can also be downloaded for further downstream analysis in third-party tools. The Illumina bead arrays analysis module is available at http://www.arrayanalysis.org . A user guide, a tutorial demonstrating the analysis of an example dataset, and R scripts are available. The module can be used as a starting point for statistical evaluation and pathway analysis provided on the website or to generate processed input data for a broad range of applications in life sciences research.

  16. Analysis list: Ar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Ar Gonad,Kidney,Prostate + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/targe...t/Ar.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Ar.5.tsv http://dbarchive.biosciencedbc.jp/...kyushu-u/mm9/target/Ar.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Ar.Gonad.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/Ar.Kidney.tsv,http://dbarchive.bioscienced...bc.jp/kyushu-u/mm9/colo/Ar.Prostate.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Gonad.gml,http://dbarchive.bioscience

  17. Ramon Llull's Ars Magna

    DEFF Research Database (Denmark)

    Jensen, Thessa

    2017-01-01

    might be a viable and valuable approach to understand some of the challenges and possibilities found in computer science and ethics. Vita Llull was born in 1232 in Palma de Mallorca, a melting pot for different cul-tures and religions at the time. Being educated at the king’s court, Llull learned...... of belief, life, and God as such. Computer Science? Llull was an inspiration for later scientists, most notably Giordano Bruno, Athanasius Kirchner, Agrippa of Nettesheim and Gottfried Wilhelm Leibniz, whose dissertation De Arte Combinatoria begins with a discussion of Llull’s Ars Magna. Umberto Eco also......-ple of Mallorca have since tried to have Llull canonised as a saint. Ars Magna A few years before his death Llull began to write the most thorough and final version of his Ars Magna, the Ars Generalis Ultima [3]. The books explain the different figures of the Ars, its principles, questions, descriptions...

  18. Update on TAO moored ORG array

    Science.gov (United States)

    Freitag, H. Paul

    1994-01-01

    During the Coupled Ocean Atmosphere Response Experiment (COARE) six TAO moorings were equipped with optical rain gauges (ORG's). In late 1993 moorings deployed on the equator at 154E and 157.5E were recovered and not redeployed as they were augmentations to the TAO array for COARE only. In December 1993, four TAO moorings were equipped with ORG's: one each at 2N, 156E and 2S, 156E and ORG doublets on the equator at 0, 156E and 0, 165E. The 2N, 156E mooring has been lost. By the end of April all sites will have been serviced and six refurbished sensors will again be deployed in the same locations.

  19. Interactive web-taxonomy for the Araceae: www.cate-araceae.org

    NARCIS (Netherlands)

    Haigh, A.; Mayo, S.J.; Croat, T.; Reynolds, L.; Mora Pinto, M.; Boyce, P.C.; Lay, L.; Bogner, J.; Clark, B.; Kostelac, C.; Hay, A.

    2009-01-01

    CATE (Creating a Taxonomic E-science) is a pilot project funded by the UK Natural Environment Research Council (NERC) to test a model of internet taxonomy which aims to construct and maintain online a full descriptive taxonomic revision as a collective enterprise carried out by the specialist

  20. [Systematic review of studies on quality of life indexed on the SciELO database].

    Science.gov (United States)

    Landeiro, Graziela Macedo Bastos; Pedrozo, Celine Cristina Raimundo; Gomes, Maria José; Oliveira, Elizabete Regina de Araújo

    2011-10-01

    Interest in the quality of life construct has increased in the same proportion as the output of instruments to measure it. In order to analyze the scientific literature on the subject to provide a reflection on this construct in Brazil, a systematic review of the SciELO database covering the period from January 2001 to December 2006 was conducted. It was divided into 3 phases: the first involving 180 publications, the second 124, and the third 10. Of the 180 publications, 77.4% consisted of production in the last three years, with growth of 32.4% from 2001 to 2006. Of these, 124 were selected for methodological analysis in accordance with the category of the study: 79 (63.9%) instrument application articles; 25 (20.1%) translation, validation, adaptation and construction of a QOL instrument; 10 (8%) qualitative studies on QOL; 5 (4%) bibliographical review, 5 (4%) on the quality of life concept. The next stage involved the use of questionnaires and/or interview scripts in order to obtain a broader consensus on perceived quality of life from the interviewees. It was seen that there was significant scientific output in the period under scrutiny, with diversification of approaches and methodologies, highlighting the complexity of the quality of life construct.

  1. The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions.

    Science.gov (United States)

    Abdulrahman, Basant A; Abdelaziz, Dalia; Thapa, Simrika; Lu, Li; Jain, Shubha; Gilch, Sabine; Proniuk, Stefan; Zukiwski, Alexander; Schatzl, Hermann M

    2017-12-14

    Prion diseases are fatal infectious neurodegenerative disorders that affect both humans and animals. The autocatalytic conversion of the cellular prion protein (PrP C ) into the pathologic isoform PrP Sc is a key feature in prion pathogenesis. AR-12 is an IND-approved derivative of celecoxib that demonstrated preclinical activity against several microbial diseases. Recently, AR-12 has been shown to facilitate clearance of misfolded proteins. The latter proposes AR-12 to be a potential therapeutic agent for neurodegenerative disorders. In this study, we investigated the role of AR-12 and its derivatives in controlling prion infection. We tested AR-12 in prion infected neuronal and non-neuronal cell lines. Immunoblotting and confocal microscopy results showed that AR-12 and its analogue AR-14 reduced PrP Sc levels after only 72 hours of treatment. Furthermore, infected cells were cured of PrP Sc after exposure of AR-12 or AR-14 for only two weeks. We partially attribute the influence of the AR compounds on prion propagation to autophagy stimulation, in line with our previous findings that drug-induced stimulation of autophagy has anti-prion effects in vitro and in vivo. Taken together, this study demonstrates that AR-12 and the AR-14 analogue are potential new therapeutic agents for prion diseases and possibly protein misfolding disorders involving prion-like mechanisms.

  2. High-resolution Auger spectroscopy on 79 MeV Ar5+, 89 MeV Ar6+, and 136 MeV Ar7+ ions after excitation by helium

    International Nuclear Information System (INIS)

    Schneider, T.

    1988-01-01

    In this thesis the atomic structure of highly excited Ar 6+ and Ar 7+ ions was studied. For this 79 MeV Ar 5+ , 89 MeV Ar 6+ , and 136 MeV Ar 7+ ions of a heavy ion accelerator were excited by a He gas target to autoionizing states and the Auger electrons emitted in the decay were measured in highly-resolving state. The spectra were taken under an observational angle of zero degree relative to the beam axis in order to minimize the kinematical broadening of the Auger lines. (orig./HSI) [de

  3. A compilation of 40Ar-39 and K-Ar ages: report 25

    International Nuclear Information System (INIS)

    Hunt, P.A.; Roddick, J.C.

    1996-01-01

    Twenty-three 40 Ar- 39 Ar age determinations (including two potassium-argon analyses) carried out by the Geological Survey of Canada are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in outline. An index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference. (author). 6 refs., 2 tabs., 1 fig

  4. Cross Sections of the 36Ar(d,α)34mCl, 40Ar(d,α)38Cl and 40Ar(d,p)41Ar Nuclear Reactions below 8.4 MeV

    Science.gov (United States)

    Engle, J W; Severin, G W; Barnhart, T E; Knutson, L D; Nickles, R J

    2011-01-01

    We have measured the cross section for production of the medically interesting isotope 34mCl, along with 38Cl and 41Ar, using deuteron bombardments of 36Ar and 40Ar below 8.4 MeV. ALICE/ASH analytical codes were employed to determine the shape of nuclear excitation functions, and experiments were performed using the University of Wisconsin tandem electrostatic accelerator to irradiate thin targets of argon gas. PMID:22041299

  5. Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells.

    Science.gov (United States)

    Fan, Lingling; Zhang, Fengbo; Xu, Songhui; Cui, Xiaolu; Hussain, Arif; Fazli, Ladan; Gleave, Martin; Dong, Xuesen; Qi, Jianfei

    2018-05-15

    Formation of the androgen receptor splicing variant 7 (AR-V7) is one of the major mechanisms by which resistance of prostate cancer to androgen deprivation therapy occurs. The histone demethylase JMJD1A (Jumonji domain containing 1A) functions as a key coactivator for AR by epigenetic regulation of H3K9 methylation marks. Here, we describe a role for JMJD1A in AR-V7 expression. While JMJD1A knockdown had no effect on full-length AR (AR-FL), it reduced AR-V7 levels in prostate cancer cells. Reexpression of AR-V7 in the JMJD1A-knockdown cells elevated expression of select AR targets and partially rescued prostate cancer cell growth in vitro and in vivo. The AR-V7 protein level correlated positively with JMJD1A in a subset of human prostate cancer specimens. Mechanistically, we found that JMJD1A promoted alternative splicing of AR-V7 through heterogeneous nuclear ribonucleoprotein F (HNRNPF), a splicing factor known to regulate exon inclusion. Knockdown of JMJD1A or HNRNPF inhibited splicing of AR-V7, but not AR-FL, in a minigene reporter assay. JMJD1A was found to interact with and promote the recruitment of HNRNPF to a cryptic exon 3b on AR pre-mRNA for the generation of AR-V7. Taken together, the role of JMJD1A in AR-FL coactivation and AR-V7 alternative splicing highlights JMJD1A as a potentially promising target for prostate cancer therapy.

  6. A Refined Astronomically Calibrated 40Ar/39Ar Age for Fish Canyon Sanidine

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Zeeden, Christian

    2011-01-01

    Intercalibration between the astronomical and radio-isotopic dating methods provides a means to improving accuracy and reducing uncertainty of an integrated, multi-chronometer geologic timescale. Here we report a high-precision 40Ar/39Ar age for the Fish Canyon sanidine (FCs) neutron fluence...... sanidine age of 0.7674±0.0022 Ma (2σ, external errors) is indistinguishable from the ID-TIMS U/Pb zircon age (0.7671±0.0019 Ma). The consistency between the astronomically calibrated 40Ar/39Ar sanidine age and U/Pb zircon age for this Quaternary unit suggests that agreement between these two radio-isotopic...... dating techniques is now achievable at better than±0.3% (2σ) in the youngest part of geologic time (

  7. Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.

    Science.gov (United States)

    Kohli, Manish; Ho, Yeung; Hillman, David W; Van Etten, Jamie L; Henzler, Christine; Yang, Rendong; Sperger, Jamie M; Li, Yingming; Tseng, Elizabeth; Hon, Ting; Clark, Tyson; Tan, Winston; Carlson, Rachel E; Wang, Liguo; Sicotte, Hugues; Thai, Ho; Jimenez, Rafael; Huang, Haojie; Vedell, Peter T; Eckloff, Bruce W; Quevedo, Jorge F; Pitot, Henry C; Costello, Brian A; Jen, Jin; Wieben, Eric D; Silverstein, Kevin A T; Lang, Joshua M; Wang, Liewei; Dehm, Scott M

    2017-08-15

    Purpose: Androgen receptor (AR) variant AR-V7 is a ligand-independent transcription factor that promotes prostate cancer resistance to AR-targeted therapies. Accordingly, efforts are under way to develop strategies for monitoring and inhibiting AR-V7 in castration-resistant prostate cancer (CRPC). The purpose of this study was to understand whether other AR variants may be coexpressed with AR-V7 and promote resistance to AR-targeted therapies. Experimental Design: We utilized complementary short- and long-read sequencing of intact AR mRNA isoforms to characterize AR expression in CRPC models. Coexpression of AR-V7 and AR-V9 mRNA in CRPC metastases and circulating tumor cells was assessed by RNA-seq and RT-PCR, respectively. Expression of AR-V9 protein in CRPC models was evaluated with polyclonal antisera. Multivariate analysis was performed to test whether AR variant mRNA expression in metastatic tissues was associated with a 12-week progression-free survival endpoint in a prospective clinical trial of 78 CRPC-stage patients initiating therapy with the androgen synthesis inhibitor, abiraterone acetate. Results: AR-V9 was frequently coexpressed with AR-V7. Both AR variant species were found to share a common 3' terminal cryptic exon, which rendered AR-V9 susceptible to experimental manipulations that were previously thought to target AR-V7 uniquely. AR-V9 promoted ligand-independent growth of prostate cancer cells. High AR-V9 mRNA expression in CRPC metastases was predictive of primary resistance to abiraterone acetate (HR = 4.0; 95% confidence interval, 1.31-12.2; P = 0.02). Conclusions: AR-V9 may be an important component of therapeutic resistance in CRPC. Clin Cancer Res; 23(16); 4704-15. ©2017 AACR . ©2017 American Association for Cancer Research.

  8. Single-crystal 40Ar/39Ar incremental heating reveals bimodal sanidine ages in the Bishop Tuff

    Science.gov (United States)

    Andersen, N. L.; Jicha, B. R.; Singer, B. S.

    2015-12-01

    The 650 km3 Bishop Tuff (BT) is among the most studied volcanic deposits because it is an extensive marker bed deposited just after the Matuyama-Brunhes boundary. Reconstructions of the vast BT magma reservoir from which high-silica rhyolite erupted have long influenced thinking about how large silicic magma systems are assembled, crystallized, and mixed. Yet, the longevity of the high silica rhyolitic melt and exact timing of the eruption remain controversial due to recent conflicting 40Ar/39Ar sanidine vs. SIMS and ID-TIMS U-Pb zircon dates. We have undertaken 21 40Ar/39Ar incremental heating ages on 2 mm BT sanidine crystals from pumice in 3 widely separated outcrops of early-erupted fall and flow units. Plateau ages yield a bimodal distribution: a younger group has a mean of 766 ka and an older group gives a range between 772 and 782 ka. The younger population is concordant with the youngest ID-TIMS and SIMS U-Pb zircon ages recently published, as well as the astronomical age of BT in marine sediment. Of 21 crystals, 17 yield older, non-plateau, steps likely affected by excess Ar that would bias traditional 40Ar/39Ar total crystal fusion ages. The small spread in older sanidine ages, together with 25+ kyr of pre-eruptive zircon growth, suggest that the older sanidines are not partially outgassed xenocrysts. A bimodal 40Ar/39Ar age distribution implies that some fraction of rhyolitic melt cooled below the Ar closure temperature at least 10 ky prior to eruption. We propose that rapid "thawing" of a crystalline mush layer released older crystals into rhyolitic melt from which sanidine also nucleated and grew immediately prior to the eruption. High precision 40Ar/39Ar dating can thus provide essential information on thermo-physical processes at the millenial time scale that are critical to interpreting U-Pb zircon age distributions that are complicated by large uncertainties associated with zircon-melt U-Th systematics.

  9. Optical characteristics of a RF DBD plasma jet in various {Ar}/ {O}_{2}Ar/O2 mixtures

    Science.gov (United States)

    Falahat, A.; Ganjovi, A.; Taraz, M.; Ravari, M. N. Rostami; Shahedi, A.

    2018-02-01

    In this paper, using the optical emission spectroscopy (OES) technique, the optical characteristics of a radiofrequency (RF) plasma jet are examined. The Ar/O2 mixture is taken as the operational gas and, the Ar percentage in the Ar/O2 mixture is varied from 70% to 95%. Using the optical emission spectrum analysis of the RF plasma jet, the excitation temperature is determined based on the Boltzmann plot method. The electron density in the plasma medium of the RF plasma jet is obtained by the Stark broadening of the hydrogen Balmer H_{β }. It is mostly seen that, the radiation intensity of Ar 4p→ 4s transitions at higher argon contributions in Ar/O2 mixture is higher. It is found that, at higher Ar percentages, the emission intensities from atomic oxygen (O) are higher and, the line intensities from the argon atoms and ions including O atoms linearly increase. It is observed that the quenching of Ar^{*} with O2 results in higher O species with respect to O2 molecules. In addition, at higher percentages of Ar in the Ar/O2 mixture, while the excitation temperature is decreased, the electron density is increased.

  10. Cross sections of the 36Ar(d,α)34mCl, 40Ar(d,α)38Cl, and 40Ar(d,p)41Ar nuclear reactions below 8.4 MeV.

    Science.gov (United States)

    Engle, J W; Severin, G W; Barnhart, T E; Knutson, L D; Nickles, R J

    2012-02-01

    We have measured the cross section for production of the medically interesting isotope (34m)Cl, along with (38)Cl and (41)Ar, using deuteron bombardments of (36)Ar and (40)Ar below 8.4 MeV. ALICE/ASH analytical codes were employed to determine the shape of nuclear excitation functions, and experiments were performed using the University of Wisconsin tandem electrostatic accelerator to irradiate thin targets of argon gas. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Classical treatment of Li2++Ar and He2++Ar collisions

    International Nuclear Information System (INIS)

    Jorge, A; Illescas, Clara; Pons, B

    2015-01-01

    Classical Trajectory Monte Carlo calculations are carried out for Li 2+ +Ar and He 2+ +Ar collisions, motivated by recent experiments on these systems. Cross sections for electron capture, projectile electron loss and target multiple ionization processes are evaluated and compared to the experimental values in the 75-500 keV/amy impact energy range. (paper)

  12. Sélection de sites web sur genre et économie

    OpenAIRE

    2017-01-01

    http://www.afedonline.com http://www.unog.ch/frames/library/bibliography/women.htm Les Femmes, bibliographie sélective 1988-1999, Bibliothèque des Nations Unies, Genève. http://www.africabib.org/womendb.html http://www.eclacpos.org Commission Economique pour l’Amérique Latine y les Caraïbes. Propose un système d’indicateurs prenant le genre en compte, “SISESIM 2001”. http://www.fao.org/Gender/en/agri-e.htm http://www.genderarena.com/genderarena/homepage.htm http://www.gn.apc.org/homenet H...

  13. Café convencional versus café orgânico: perspectivas de sustentabilidade socioeconômica dos agricultores familiares do Espírito Santo

    OpenAIRE

    Siqueira,Haloysio Miguel de; Souza,Paulo Marcelo de; Ponciano,Niraldo José

    2011-01-01

    Esse artigo enfoca a viabilidade de investimento na produção de café arábica, no Estado do Espírito Santo, comparando os sistemas convencional e orgânico, para identificar o que proporciona maior sustentabilidade socioeconômica aos produtores familiares. Os métodos de avaliação econômica utilizados foram o valor presente líquido, a taxa interna de retorno e o tempo de retorno do capital investido. Também foi feita a análise de sensibilidade. Demonstrou-se que ambos os sistemas de produção for...

  14. PENYEBARAN INFORMASI MENGGUNAKAN WWW (WORLD WIDE WEB

    Directory of Open Access Journals (Sweden)

    Ika Atman Satya

    2011-12-01

    Full Text Available Media Informasi secara tradisional telah kita kenai dengan menggunakan koran, televisi, radio dan buku referensi. Media informasi tersebut untuk penyebarannya memerlukan penunjang agar informasi tersebut dapat disebarkan secara lutis. Selain penggunaan media tradisional tersebut penyebaran informasi dengan menggunakan jaringan komputer Internet juga berkembang. Salah satu cara penyebaran informasi dengan menggunakan aplikasi WWW (World Wide Web yang mempunyai kemampuan menggabungkan gambar, text dan suara secara interaktif. Pada tulisan ini akan dibahas tentang kemampuan, penggunaan dan pengembangan server WWW.

  15. Thermal significance of potassium feldspar K-Ar ages inferred from /sup 40/Ar//sup 39/Ar age spectrum results

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, T.M.; McDougall, I. (Australian National Univ., Canberra. Research School of Earth Sciences)

    1982-10-01

    /sup 40/Ar//sup 39/Ar age spectrum analyses of three microcline separates from the Separation Point Batholith, northwest Nelson, New Zealand, which cooled slowly through the temperature zone of partial radiogenic /sup 40/Ar accumulation are characterized by a linear age increase over the first 65 percent of gas release with the lowest ages corresponding to the time that the samples cooled below about 100/sup 0/C. The last 35 percent of /sup 39/Ar released from the microclines yields plateau ages which reflect the different bulk mineral ages, and correspond to cooling temperatures between about 130 to 160/sup 0/C. Theoretical calculations confirm the likelihood of diffusion gradients in feldspars cooling at rates =< 5/sup 0/C-Ma/sup -1/. Diffusion parameters calculated from the /sup 39/Ar release yield an activation energy, E = 28.8 +- 1.9 kcal-mol/sup -1/, and a frequency factor/grain size parameter, D/sub 0//l/sup 2/ = 5.6sub(-3.9)sup(+14) sec/sup -1/. This Arrhenius relationship corresponds to a closure temperature of 132 +- 13/sup 0/C which is very similar to the independently estimated temperature. From the observed diffusion compensation correlation, this D/sub 0//l/sup 2/ implies an average diffusion half-width of about 3 ..mu..m, similar to the half-width of the perthite lamellae in the feldspars. The results are discussed.

  16. 40Ar-39Ar dating of hornfels dredged near the Japan trench

    International Nuclear Information System (INIS)

    Takigami, Yutaka; Fujioka, Kantaro

    1989-01-01

    During the KH 81-3 Cruise of the R/V Hakuho-Maru, biotite-bearing hornfelses were dredged from the landward slope of the Japan Trench. Bulk sample and separated biotite were dated by the 40 Ar- 39 Ar method and they showed 40 Ar- 39 Ar ages of 28.9±1.4 Ma and 28.5±1.4 Ma, respectively. This would indicate that biotite was formed at about 29 Ma by the thermal metamorphism which might have related with some magmatic activity. In this magmatic activity was caused by the subducting oceanic plate in the similar conditions at present, it seems to have occurred at a place too close to the present trench axis. This discrepancy could be explained by such processes as the change of the angle of the subducting plate, the moving of the trench axis by tectonic erosion and so on. However, more age data are required to solve this discrepancy. (author)

  17. 40Ar/39Ar and K/Ar whole rock age constraints on the timing of regional deformation, South Coast of New South Wales, Lachlan Fold Belt, Southeastern Australia: problems and implications

    International Nuclear Information System (INIS)

    Phillips, D.; Fergusson, C.L.

    1999-01-01

    Full text: Subduction complex rocks are well exposed on the south coast of New South Wales around Batemans Bay. Farther south in the Narooma and Bermagui region, Offier et al (1998) have determined two 40 Ar/ 39 Ar ages of 450 ± 3 Ma and 445 ± 2 Ma. They argued that these ages constrain the timing of intense underplating-related deformation and we have undertaken farther work, from an area south of Batemans Bay, to test this suggestion. The 40 Ar/ 39 Ar method applied to fine-grained, low temperature metamorphic rocks, such as slates, is beset by the problem of recoil loss and/or redistribution of 39 Ar during the irradiation process. Another problem is the difficulty of distinguishing between the contributions to 40 Ar/ 39 Ar spectra from illite/muscovite grown during the cleavage-producing deformation and detrital muscovite/illite. In the current study, four slate samples, with variable contents of detrital white mica, were analysed by both the K-Ar and 40 Ar/ 39 Ar step-heating methods. A separate of detrital white mica from one slate sample yields a plateau age of 500 ± 2 Ma. This result indicates that inheritance has not been eliminated by metamorphism as is commonly assumed and that the 40 Ar/ 39 Ar ages provide only a maximum estimate for the timing of deformation. 40 Ar/ 39 Ar analyses of state chips yield discordant, saddle-shaped age spectra, with minimum, within-saddle' ages of ca. 420 Ma. Two slate samples give identical 40 Ar/ 39 Ar integrated ages of 455 ± 2 Ma. One sample contains relatively abundant detrital bedding-parallel mica flakes that are locally oblique to the regional cleavage in the rock. The 40 Ar/ 39 Ar ages are some 20 Ma older than K-Ar ages for these same samples, suggesting that recoil loss of 39 Ar may also have affected these slates. Both recoil loss of 39 Ar and inherited white micas will yield elevated apparent ages, thus providing only maximum ages for the cleavage-producing deformation. Two other samples from slaty tectonic

  18. Androgen Receptor (AR) Physiological Roles in Male and Female Reproductive Systems: Lessons Learned from AR-Knockout Mice Lacking AR in Selective Cells1

    Science.gov (United States)

    Chang, Chawnshang; Lee, Soo Ok; Wang, Ruey-Sheng; Yeh, Shuyuan; Chang, Ta-Min

    2013-01-01

    ABSTRACT Androgens/androgen receptor (AR) signaling is involved primarily in the development of male-specific phenotypes during embryogenesis, spermatogenesis, sexual behavior, and fertility during adult life. However, this signaling has also been shown to play an important role in development of female reproductive organs and their functions, such as ovarian folliculogenesis, embryonic implantation, and uterine and breast development. The establishment of the testicular feminization (Tfm) mouse model exploiting the X-linked Tfm mutation in mice has been a good in vivo tool for studying the human complete androgen insensitivity syndrome, but this mouse may not be the perfect in vivo model. Mouse models with various cell-specific AR knockout (ARKO) might allow us to study AR roles in individual types of cells in these male and female reproductive systems, although discrepancies are found in results between labs, probably due to using various Cre mice and/or knocking out AR in different AR domains. Nevertheless, no doubt exists that the continuous development of these ARKO mouse models and careful studies will provide information useful for understanding AR roles in reproductive systems of humans and may help us to develop more effective and more specific therapeutic approaches for reproductive system-related diseases. PMID:23782840

  19. Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells.

    Science.gov (United States)

    Olson, Brian M; Gamat, Melissa; Seliski, Joseph; Sawicki, Thomas; Jeffery, Justin; Ellis, Leigh; Drake, Charles G; Weichert, Jamey; McNeel, Douglas G

    2017-12-01

    Androgen deprivation is the primary therapy for recurrent prostate cancer, and agents targeting the androgen receptor (AR) pathway continue to be developed. Because androgen-deprivation therapy (ADT) has immmunostimulatory effects as well as direct antitumor effects, AR-targeted therapies have been combined with other anticancer therapies, including immunotherapies. Here, we sought to study whether an antigen-specific mechanism of resistance to ADT (overexpression of the AR) may result in enhanced AR-specific T-cell immune recognition, and whether this might be strategically combined with an antitumor vaccine targeting the AR. Androgen deprivation increased AR expression in human and murine prostate tumor cells in vitro and in vivo The increased expression persisted over time. Increased AR expression was associated with recognition and cytolytic activity by AR-specific T cells. Furthermore, ADT combined with vaccination, specifically a DNA vaccine encoding the ligand-binding domain of the AR, led to improved antitumor responses as measured by tumor volumes and delays in the emergence of castrate-resistant prostate tumors in two murine prostate cancer models (Myc-CaP and prostate-specific PTEN-deficient mice). Together, these data suggest that ADT combined with AR-directed immunotherapy targets a major mechanism of resistance, overexpression of the AR. This combination may be more effective than ADT combined with other immunotherapeutic approaches. Cancer Immunol Res; 5(12); 1074-85. ©2017 AACR . ©2017 American Association for Cancer Research.

  20. The 40Ar/39Ar and U/Pb dating of young rhyolites in the Kos-Nisyros volcanic complex, Eastern Aegean Arc, Greece: Age discordance due to excess 40Ar in biotite

    Science.gov (United States)

    Bachmann, O.; Schoene, B.; Schnyder, C.; Spikings, R.

    2010-08-01

    High-precision dating of Quaternary silicic magmas in the active Kos-Nisyros volcanic center (Aegean Arc, Greece) by both 40Ar/39Ar on biotite and U/Pb on zircon reveals a complex geochronological story. U/Pb ID-TIMS multi and single-grain zircon analyses from 3 different units (Agios Mammas and Zini domes, Kefalos Serie pyroclasts) range in age from 0.3 to 0.5 to 10-20 Ma. The youngest dates provide the maximum eruption age, while the oldest zircons indicate inheritance from local continental crust (Miocene and older). Step-heating 40Ar/39Ar experiments on 1-3 crystals of fresh biotite yielded highly disturbed Ar-release patterns with plateau ages typically older than most U/Pb ages. These old plateau ages are probably not a consequence of inheritance from xenocrystic biotites because Ar diffuses extremely fast at magmatic temperatures and ratios are reset within a few days. On the basis of (1) elevated and/or imprecise 40Ar/36Ar ratios, (2) shapes of the Ar release spectra, and (3) a high mantle 3He flux in the Kos-Nisyros area, we suggest that biotite crystals retained some mantle 40Ar that led to the observed, anomalously old ages. In contrast, sanidine crystals from the only sanidine-bearing unit in the Kos-Nisyros volcanic center (the caldera-forming Kos Plateau Tuff) do not appear to store any excess 40Ar relative to atmospheric composition. The eastern edge of the Aegean Arc is tectonically complex, undergoing rapid extension and located close to a major structural boundary. In such regions, which are characterized by high fluxes of mantle volatiles, 40Ar/39Ar geochronology on biotite can lead to erroneous results due to the presence of excess 40Ar and should be checked either against 40Ar/39Ar sanidine or U/Pb zircon ages.

  1. Accurate and precise 40Ar/39Ar dating by high-resolution, multi-collection, mass spectrometry

    DEFF Research Database (Denmark)

    Storey, Michael; Rivera, Tiffany; Flude, Stephanie

    New generation, high resolution, multi-collector noble gas mass spectrometers equipped with ion-counting electron multipliers provide opportunities for improved accuracy and precision in 40Ar/39Ar dating. Here we report analytical protocols and age cross-calibration studies using a NU-Instruments......New generation, high resolution, multi-collector noble gas mass spectrometers equipped with ion-counting electron multipliers provide opportunities for improved accuracy and precision in 40Ar/39Ar dating. Here we report analytical protocols and age cross-calibration studies using a NU......-Instruments multi-collector Noblesse noble gas mass spectrometer configured with a faraday detector and three ion-counting electron multipliers. The instrument has the capability to measure several noble gas isotopes simultaneously and to change measurement configurations instantaneously by the use of QUAD lenses...... (zoom optics). The Noblesse offer several advantages over previous generation noble gas mass spectrometers and is particularly suited for single crystal 40Ar/39Ar dating because of: (i) improved source sensitivity (ii) ion-counting electron multipliers, which have much lower signal to noise ratios than...

  2. 40Ar/ 39Ar ages and paleomagnetism of São Miguel lavas, Azores

    Science.gov (United States)

    Johnson, Catherine L.; Wijbrans, Jan R.; Constable, Catherine G.; Gee, Jeff; Staudigel, Hubert; Tauxe, Lisa; Forjaz, Victor-H.; Salgueiro, Mário

    1998-08-01

    We present new 40Ar/ 39Ar ages and paleomagnetic data for São Miguel island, Azores. Paleomagnetic samples were obtained for 34 flows and one dike; successful mean paleomagnetic directions were obtained for 28 of these 35 sites. 40Ar/ 39Ar age determinations on 12 flows from the Nordeste complex were attempted successfully: ages obtained are between 0.78 Ma and 0.88 Ma, in contrast to published K-Ar ages of 1 Ma to 4 Ma. Our radiometric ages are consistent with the reverse polarity paleomagnetic field directions, and indicate that the entire exposed part of the Nordeste complex is of a late Matuyama age. The duration of volcanism across São Miguel is significantly less than previously believed, which has important implications for regional melt generation processes, and temporal sampling of the geomagnetic field. Observed stable isotope and trace element trends across the island can be explained, at least in part, by communication between different magma source regions at depth. The 40Ar/ 39Ar ages indicate that our normal polarity paleomagnetic data sample at least 0.1 Myr (0-0.1 Ma) and up to 0.78 Myr (0-0.78 Ma) of paleosecular variation and our reverse polarity data sample approximately 0.1 Myr (0.78-0.88 Ma) of paleosecular variation. Our results demonstrate that precise radiometric dating of numerous flows sampled is essential to accurate inferences of long-term geomagnetic field behavior. Negative inclination anomalies are observed for both the normal and reverse polarity time-averaged field. Within the data uncertainties, normal and reverse polarity field directions are antipodal, but the reverse polarity field shows a significant deviation from a geocentric axial dipole direction.

  3. Application of quadrupole mass spectrometer to the 40Ar-39Ar geochronological study

    International Nuclear Information System (INIS)

    Takigami, Yutaka; Nishijima, Tadashi; Koike, Toshio; Okuma, Kouichi.

    1984-01-01

    A Quadrupole Mass Spectrometer (QMS) has commonly been used for qualitative analyses of gases in organic chemistry or for monitoring the vacuum conditions in industrial machines. No attempt has been made, however, to apply it to geochronological studies because of its disadvantages such as the difficulty in obtaining precise isotope ratios due to triangular peak shapes and poor reproducibility. On the other hand, there are advantages that a QMS is relatively inexpensive and gives a shorter scanning time for analysis compared with a sector type mass spectrometer. The latter characteristics is useful for 40 Ar/ 39 Ar geochronological studies, since it gives a lower background in the QMS and the possibility to obtain many more data from one sample in a limited time. In this study, we have tried to improve a commercial QMS at many parts, such as rf-generator, quadrupole, ionization chamber, source magnet, and so on, in order to meet the requirements to use it for geochronological studies. With the use of the improved QMS equipped with an on-line microcomputer, we could obtain Ar isotope data which are sufficiently precise for the 40 Ar/ 39 Ar geochronological studies. (author)

  4. ARS-Media for excel instruction manual

    Science.gov (United States)

    ARS-Media for Excel Instruction Manual is the instruction manual that explains how to use the Excel spreadsheet ARS-Media for Excel application. ARS-Media for Excel Instruction Manual is provided as a pdf file....

  5. The thermal history of the Lhasa Block, South Tibetan Plateau based on FTD and Ar-Ar dating

    CERN Document Server

    Yang, T F; Lo Chong Huah; Chung, S L; Tien, R L; Xu, R; Deng, W

    1999-01-01

    Twelve basement samples were collected from South Tibet Plateau for FTD and Ar-Ar analysis to demonstrate their uplifting history since Cenozoic era. The preliminary results from different minerals with different closure temperatures, including apatite and zircon for fission-track dating, and K-feldspar, biotite for Ar-Ar dating, show that at least four stages of thermal history can be recognized in the studied area.

  6. The thermal history of the Lhasa Block, South Tibetan Plateau based on FTD and Ar-Ar dating

    International Nuclear Information System (INIS)

    Yang, T.F.; Wang, J.R.; Lo, C.H.; Chung, S.L.; Tien, R.L.; Xu, R.; Deng, W.

    1999-01-01

    Twelve basement samples were collected from South Tibet Plateau for FTD and Ar-Ar analysis to demonstrate their uplifting history since Cenozoic era. The preliminary results from different minerals with different closure temperatures, including apatite and zircon for fission-track dating, and K-feldspar, biotite for Ar-Ar dating, show that at least four stages of thermal history can be recognized in the studied area

  7. Permeabilidade ao ar em Latossolo Vermelho sob diferentes sistemas de manejo

    Directory of Open Access Journals (Sweden)

    Sueli Rodrigues

    2011-02-01

    Full Text Available A permeabilidade ao ar pode ser utilizada para avaliar alterações que ocorrem na estrutura do solo em virtude da adoção de diferentes sistemas de manejo. Este estudo testou a hipótese de que o menor revolvimento do solo sob sistema plantio direto resulta na formação de poros mais contínuos e melhor condição de aeração no solo. O objetivo deste trabalho foi avaliar, por meio da permeabilidade ao ar (Ka, da porosidade de aeração (εa e dos índices de continuidade de poros (K1 e N, a aeração em um Latossolo Vermelho distrófico sob preparo convencional (PC e sistema plantio direto (SPD. Oitenta amostras de solo (2 tratamentos x 2 profundidades x 20 repetições com estrutura indeformada foram coletadas de cada sistema de manejo do solo nas profundidades de 0-0,10 e 0,10-0,20 m em área experimental do Instituto Agronômico do Paraná, no município de Ponta Grossa, Paraná. Depois de saturadas e equilibradas em seis potenciais mátricos (-2, -6, -10, -30, -70 e -100 kPa, determinou-se a permeabilidade ao ar e a porosidade de aeração em cada potencial. Também foram determinados a densidade do solo, a densidade de partícula, o carbono orgânico e a porosidade. A densidade do solo não consistiu em fator limitante, ficando abaixo do limite crítico para solos argilosos nos dois sistemas. No SPD, o maior volume de microporos resultou em maior retenção de água no intervalo de umidade avaliado (-2 a -100 kPa e em maior volume de poros bloqueados para o fluxo de ar (εb, ou seja, redução de Ka. Na profundidade avaliada (00,20 m, os índices de continuidade de poros (K1 e N revelaram que o PC apresentou poros mais contínuos do que o SPD, contradizendo a hipótese testada.

  8. High-resolution 40Ar/39Ar chronology of multiple intrusion igneous complexes

    Science.gov (United States)

    Foland, K. A.; Chen, J.-F.; Linder, J. S.; Henderson, C. M. B.; Whillans, I. M.

    1989-06-01

    The Mount Brome complex of the Monteregian province of southern Quebec, Canada, consits of several major intrusions ranging compositionally from gabbro to syenite. The relative ages of these intrusives have been investigated with high-resolution 40Ar/39Ar analyses, including a specially designed irradiation configuration to cancel the effects of fluence gradients. Small yet distinct apparent age differences are observed. While a number of analytical and geological factors could be proposed to explain the small variations, evaluation of these suggests the age differences reflect those in emplacement times. The gabbro and nepheline diorite were emplaced within a short span 123.1 Ma ago. Generally more evolved lithologies (biotite monzodiorite, pulaskite, nordmarkite) appear to have been emplaced within a restricted interval 1.4±0.3 Ma later. Whole-rock Rb-Sr systematics do not give acceptable isochrons because of significant scatter interpreted to reflect initial 87Sr/86Sr heterogeneities resulting from crustal contamination. Considering the variations in initial ratio, the Rb-Sr data are consistent with the 40Ar/39Ar age.

  9. Developing a chronostratigraphic tool for climatic archives: absolute dating (K/Ar and 40Ar/39Ar) and paleo-magnetism applied to lavas

    International Nuclear Information System (INIS)

    Sasco, Romain

    2015-01-01

    The understanding of climatic mechanisms and rapid climate changes requires a high-resolution, robust, and precise timescale which allows long-distance and multi-archives correlations.An appropriate tool to construct such a timescale is provided by the Earth magnetic field (EMF). The EMF is independent from climatic variations and its past evolution, global at the surface of the Earth, is recorded by most of the geological/climatic archives. Sedimentary sequences provide continuous records of relative intensities of the EMF on timescales usually based on ice core age models or orbital tuning. Lavas, though discontinuously emitted through time, record the absolute intensity of the EMF during their cooling at the surface of the Earth. Lavas are dated using 2 complementary methods: 40 Ar/ 39 Ar and K-Ar, both independent from climatic parameters. Lavas have therefore the potential to deliver tie-points (age - paleo-intensity couples) enabling the time calibration of sedimentary sequences and their transfer onto absolute intensity scale and chronological time scale. This timescale can then be transferred to other climatic archives. The present study focusses on the last 200 ka with lavas sampled from young volcanoes of Ardeche (South Massif Central, France) and recent phases of volcanism in the Canary Islands. Lava flows from Ardeche provided un-exploitable paleo-intensity results and ages with large uncertainties. Therefore, they failed to provide suitable tie-points. However, our geochronological results evidence how crucial the combination of both the K-Ar and 40 Ar/ 39 Ar methods is to test the accuracy and geological meaning of the ages. Ardeche lavas have abundant mantellic and crustal xenoliths, potential carriers of excess 40 Ar*. Our study suggests that the argon excess is located in sites that decrepitate at low temperature (≤600 C). Because 40 Ar/ 39 Ar ages are not affected by excess 40 Ar*, they provide reliable results. The new age dataset indicates

  10. A refined astronomically calibrated 40Ar/39Ar age for Fish Canyon sanidine

    NARCIS (Netherlands)

    Rivera, T.A.; Storey, M.; Zeeden, C.; Hilgen, F.J.; Kuiper, K.

    2011-01-01

    Intercalibration between the astronomical and radio-isotopic dating methods provides a means to improving accuracy and reducing uncertainty of an integrated, multi-chronometer geologic timescale. Here we report a high-precision 40Ar/39Ar age for the FishCanyon sanidine (FCs) neutron fluence monitor,

  11. Call for Development of New Mineral Standards for 40Ar/39Ar Dating

    Science.gov (United States)

    Deino, A. L.; Turrin, B. D.; Renne, P. R.; Hemming, S. R.

    2015-12-01

    Age determination via the 40Ar/39Ar dating method relies on the intercomparison of measured 40Ar*/39ArK ratios of geological unknowns with those of co-irradiated mineral standards. Good analytical procedure dictates that these ratios (and the evolution of the Ar ion beams underpinning them) be as similar as practical for the greatest accuracy. Unfortunately, throughout several intervals of the geological time scale this 'best practice' cannot be achieved with existing widely used standards. Only two internationally utilized sanidine standards are available for the middle to late Cenozoic: the Alder Creek Rhyolite sanidine (ACs), at ~1.2 Ma (Turrin et al., 1994; Nomade et al., 2005), and the Fish Canyon Tuff sanidine (FCs) at ~28.2 Ma (e.g., Kuiper et al., 2008; Renne et al, 2011). The situation is even worse throughout much of the rest of the Phanerozoic, as the next oldest standard in common use is the Hb3gr hornblende standard with an age of ~1.1 Ga (Turner, 1971; Jourdan et al., 2006). We propose, as a community effort, the development a set of standards covering the entire target range of high-precision 40Ar/39Ar dating, i.e. the Phanerozoic. Their ages would be stepped in a regular fashion with no more than approximately a factor of 3 between standards, such that in the worse case the 40Ar*/39Ar ratios of standards and unknown need differ by no more than a factor of two. While somewhat arbitrary, an approximately 3 X age progression allows the entire time scale to be covered by a manageable number of standards. Anchoring the progression in the widely used ACs, FCs, and Hb3gr (in bold, below) yields the following set of suggested standard ages: 0.4, 1.2, 3.3, 9.4, 28.2, 95, 320, and 1100 Ma. A suitable standard should be highly reproducible in age at the grain-to-grain and sub-grain levels, and highly radiogenic. The mineral should be abundant and easily separated from the host rock. These criteria may be most easily achieved by focusing on sanidine phenocrysts

  12. Spectroscopic and electric dipole properties of Sr+Ar and SrAr systems including high excited states

    Science.gov (United States)

    Hamdi, Rafika; Abdessalem, Kawther; Dardouri, Riadh; Al-Ghamdi, Attieh A.; Oujia, Brahim; Gadéa, Florent Xavier

    2018-01-01

    The spectroscopic properties of the fundamental and several excited states of Sr+Ar and SrAr, Van der Waals systems are investigated by employing an ab initio method in a pseudo-potential approach. The potential energy curves and the spectroscopic parameters are displayed for the 1-10 2Σ+, 1-6 2Π and 1-3 2Δ electronic states of the Sr+Ar molecule and for the 1-6 1Σ+, 1-4 3Σ+, 1-3 1,3Π and 1-3 1,3Δ states of the neutral molecule SrAr. In addition, from these curves, the vibrational levels and their energy spacing are deduced for Σ+, Π and Δ symmetries. The spectra of the permanent and transition dipole moments are studied for the 1,3Σ+ states of SrAr, which are considered to be two-electron systems and 2Σ+ states of the single electron Sr+Ar ion. The spectroscopic parameters obtained for each molecular system are compared with previous theoretical and experimental works. A significant correlation revealed the accuracy of our results.

  13. Skolotāju uztvertā stresa saistība ar apmierinātību ar darbu

    OpenAIRE

    Dejus, Ilze

    2014-01-01

    Pētījuma „Skolotāju uztvertā stresa saistība ar apmierinātību ar darbu” mērķis, pamatojoties uz teorētisko analīzi, pētīt skolotāju uztvertā stresa saistību ar apmierinātību ar darbu. Pētījuma jautājumi: 1.Vai pastāv statistiski nozīmīga saistība starp skolotāju uztvertā stresa līmeni un apmierinātību ar darbu? 2.Vai pastāv statistiski nozīmīgas atšķirības starp Liepājas 15.vidusskolas un Grobiņas novada skolotāju uztvertā stresa līmeni un apmierinātību ar darbu? Aptaujāti 113 skolot...

  14. Combined U-Th/He and 40Ar/39Ar geochronology of post-shield lavas from the Mauna Kea and Kohala volcanoes, Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Aciego, S.M.; Jourdan, F.; DePaolo, D.J.; Kennedy, B.M.; Renne, P.R.; Sims, K.W.W.

    2009-10-01

    Late Quaternary, post-shield lavas from the Mauna Kea and Kohala volcanoes on the Big Island of Hawaii have been dated using the {sup 40}Ar/{sup 39}Ar and U-Th/He methods. The objective of the study is to compare the recently demonstrated U-Th/He age method, which uses basaltic olivine phenocrysts, with {sup 40}Ar/{sup 39}Ar ages measured on groundmass from the same samples. As a corollary, the age data also increase the precision of the chronology of volcanism on the Big Island. For the U-Th/He ages, U, Th and He concentrations and isotopes were measured to account for U-series disequilibrium and initial He. Single analyses U-Th/He ages for Hamakua lavas from Mauna Kea are 87 {+-} 40 ka to 119 {+-} 23 ka (2{sigma} uncertainties), which are in general equal to or younger than {sup 40}Ar/{sup 39}Ar ages. Basalt from the Polulu sequence on Kohala gives a U-Th/He age of 354 {+-} 54 ka and a {sup 40}Ar/{sup 39}Ar age of 450 {+-} 40 ka. All of the U-Th/He ages, and all but one spurious {sup 40}Ar/{sup 39}Ar ages conform to the previously proposed stratigraphy and published {sup 14}C and K-Ar ages. The ages also compare favorably to U-Th whole rock-olivine ages calculated from {sup 238}U - {sup 230}Th disequilibria. The U-Th/He and {sup 40}Ar/{sup 39}Ar results agree best where there is a relatively large amount of radiogenic {sup 40}Ar (>10%), and where the {sup 40}Ar/{sup 36}Ar intercept calculated from the Ar isochron diagram is close to the atmospheric value. In two cases, it is not clear why U-Th/He and {sup 40}Ar/{sup 39}Ar ages do not agree within uncertainty. U-Th/He and {sup 40}Ar/{sup 39}Ar results diverge the most on a low-K transitional tholeiitic basalt with abundant olivine. For the most alkalic basalts with negligible olivine phenocrysts, U-Th/He ages were unattainable while {sup 40}Ar/{sup 39}Ar results provide good precision even on ages as low as 19 {+-} 4 ka. Hence, the strengths and weaknesses of the U-Th/He and {sup 40}Ar/{sup 39}Ar methods are

  15. The mass of sup 3 sup 2 Ar and sup 3 sup 3 Ar for fundamental tests

    CERN Document Server

    Blaum, K; Beck, D; Bollen, G; Herfurth, F; Kellerbauer, A G; Kluge, H J; Sauvan, E; Schwarz, S

    2003-01-01

    Masses of the short-lived radionuclides sup 3 sup 2 Ar (T sub 1 sub / sub 2 = 98 ms) sup 3 sup 3 Ar (T sub 1 sub / sub 2 = 173 ms) have been determined with the Penning trap mass spectrometer ISOLTRAP. Relative uncertainties of 6.0 x 10 sup - sup 8 (delta m = 1.8 keV) and 1.4 x 10 sup - sup 8 (delta m = 0.44 keV), respectively, have been achieved. At present, these new mass data serve as the most stringent test of the quadratic form of the isobaricmultiplet mass equation IMME. Furthermore, the improved accuracy for the mass of sup 3 sup 2 Ar yields a better constraint on scalar contributions to the weak interaction. New mass values have also been measured for sup 4 sup 4 Ar and sup 4 sup 5 Ar, and a 20 sigma deviation for sup 4 sup 4 Ar from the literature value was found and interpreted.

  16. Quantum treatment of the Ar-HI photodissociation dynamics

    International Nuclear Information System (INIS)

    Lopez-Lopez, Sergio; Prosmiti, Rita; Garcia-Vela, Alberto

    2004-01-01

    A wave packet simulation of the ultraviolet photolysis dynamics of Ar-HI(v=0) is reported. Cluster photodissociation is started from two different initial states, namely, the ground van der Waals (vdW) and the first excited vdW bending state, associated with the Ar-I-H and Ar-H-I isomeric forms of the system, respectively. Formation of Ar-I radical products is investigated over the energy range of the cluster absorption spectrum. It is found that the yield of bound Ar-I radical complexes is typically 90%-100% and 70%-80% for the initial states associated with the Ar-I-H and Ar-H-I isomers, respectively. This result is in agreement with the experimentally observed time-of-flight spectrum of the hydrogen fragment produced after Ar-HI photodissociation. The high Ar-I yield is explained mainly by the small amount of energy available for the radical that is converted into internal energy in the photofragmentation process, which enhances the Ar-I survival probability. Quantum interference effects manifest themselves in structures in the angular distribution of the hydrogen fragment, and in pronounced rainbow patterns in the rotational distributions of the Ar-I radical

  17. Microclima e produção de videiras 'Niágara rosada' em cultivo orgânico sob cobertura plástica

    Directory of Open Access Journals (Sweden)

    Flávia Comiran

    2012-03-01

    Full Text Available O uso de coberturas plásticas sobre vinhedos tem aumentado no Sul do Brasil, visando a atenuar limitações climáticas. Este estudo objetivou quantificar alterações micrometeorológicas causadas por cobertura plástica e seus efeitos no desenvolvimento e na produção de videiras 'Niágara Rosada', em cultivo orgânico. O estudo foi realizado em Bento Gonçalves-RS, num vinhedo conduzido em sistema latada e submetido a dois ambientes: em céu aberto e coberto por plástico transparente (160µm em arcos descontínuos. Nos dois ambientes, foram monitoradas radiação fotossinteticamente ativa (RFA e temperatura do ar. Avaliaram-se fenologia, índice de área foliar (IAF, peso e diâmetro de bagas, teor de sólidos solúveis e acidez total titulável, incidência de doenças fúngicas e rendimento. A cobertura reduziu em um terço a RFA incidente (-34% e aumentou as temperaturas máximas do ar (+3,1ºC. Ela acelerou o ciclo vegetativo das videiras até a maturação, mas retardou a queda de folhas. A cobertura promoveu incrementos de IAF, duração da área foliar e produção de uvas, de 12,3 para 27,1 t ha-1. Não foi observada incidência de doenças fúngicas no vinhedo coberto. Portanto, a cobertura plástica sobre vinhedos é uma alternativa importante na produção de uvas de mesa no Sul do Brasil, em cultivo orgânico.

  18. http://www.bioline.org.br/js 120 Omental Torsion Mimicking Acute ...

    African Journals Online (AJOL)

    jen

    This review discusses a 38 year old patient with all the signs and symptoms of acute appendicitis. At surgery a normal appendix and serosanguinous fluid were observed. Further routine exploration disclosed a twisted omentum. This segment was excised. Patient recovered quickly. There is a need for exploration of the ...

  19. 12 July 2015 www.criticalcare.org.za Europa Organisation Africa Tel ...

    African Journals Online (AJOL)

    2015-07-12

    Jul 12, 2015 ... To determine deviations in ETT Pcuff from the recommended range during the intervals between ... For the entire study, 588 events causing Pcuff alterations were recorded. .... line with cervical spine/cricoid cartilage at C6.

  20. http://www.bioline.org.br/js 15 Practices of Makerere University ...

    African Journals Online (AJOL)

    jen

    anatomy dissection are fundamental to the learning of human anatomy and eventual practice of medicine. ... Results:The overall response rate was 26.9%. Of the 82 ... manual and dissecting show significant sexual bias. There is a need to ...

  1. Ars Baltica-verkoston puheenjohtajuus Suomeen Risto Ruohoselle

    Index Scriptorium Estoniae

    1999-01-01

    1990. a. loodud võrgustiku Ars Baltica sekretariaat (Ars Baltica Contact Point & Communication Center) tuleb Kielist Tallinnasse Eesti kultuuriministeeriumi kuni aastani 2002 (Suur-Karja 23). Ars Baltica (ühendus)

  2. Single grains, thermal histories, and the 40Ar/39Ar method

    International Nuclear Information System (INIS)

    Wright, Norrie

    1989-01-01

    A key part in unraveling the history of the physical evolution of the earth is knowledge of the earth's thermal history. 40 Ar/ 39 Ar step heating of mineral samples provides a means of defining a local thermal history. to do this accurately the challenge is to extract meaningful diffusion parameters from a mineral's Arrhenius plot. In the case of biotite single grains, where the laboratory release of argon is a complex process, this can be a difficult task. (12 refs., 5 figs.)

  3. 40Ar/39Ar ages of adularia from the Golden Cross, Neavesville, and Komata epithermal deposits, Hauraki Goldfield, New Zealand

    International Nuclear Information System (INIS)

    Mauk, J.L.; Hall, C.M.

    2004-01-01

    New 40 Ar/ 39 Ar ages of adularia from three epithermal vein deposits in the Hauraki Goldfield constrain when these deposits formed. Adularia from veins at Neavesville has 40 Ar/ 39 Ar plateau and isochron ages of 6.89 ± 0.02 and 6.86 ± 0.02 Ma, respectively, similar to the 40 Ar/ 39 Ar plateau and isochron ages of adularia from veins at Golden Cross of 6.96 ± 0.04 and 6.93 ± 0.03 Ma, respectively. In contrast, Komata mineralisation formed at 5.99 ± 0.02 to 6.07 ± 0.03 Ma, based on the 40 Ar/ 39 Ar isochron and plateau ages of the adularia in these veins, similar to the previously reported 6.0 Ma age of mineralisation at Waihi/Favona. These preliminary data suggest that mineralisation in the Hauraki Goldfields occurred episodically. (author). 19 refs., 3 figs., 1 tab

  4. minepath.org: a free interactive pathway analysis web server.

    Science.gov (United States)

    Koumakis, Lefteris; Roussos, Panos; Potamias, George

    2017-07-03

    ( www.minepath.org ) is a web-based platform that elaborates on, and radically extends the identification of differentially expressed sub-paths in molecular pathways. Besides the network topology, the underlying MinePath algorithmic processes exploit exact gene-gene molecular relationships (e.g. activation, inhibition) and are able to identify differentially expressed pathway parts. Each pathway is decomposed into all its constituent sub-paths, which in turn are matched with corresponding gene expression profiles. The highly ranked, and phenotype inclined sub-paths are kept. Apart from the pathway analysis algorithm, the fundamental innovation of the MinePath web-server concerns its advanced visualization and interactive capabilities. To our knowledge, this is the first pathway analysis server that introduces and offers visualization of the underlying and active pathway regulatory mechanisms instead of genes. Other features include live interaction, immediate visualization of functional sub-paths per phenotype and dynamic linked annotations for the engaged genes and molecular relations. The user can download not only the results but also the corresponding web viewer framework of the performed analysis. This feature provides the flexibility to immediately publish results without publishing source/expression data, and get all the functionality of a web based pathway analysis viewer. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  5. HDR-Aggregate Read Service (ARS)

    Data.gov (United States)

    Department of Veterans Affairs — ARS is a SOAP web service exposed over HTTPS that provides an aggregated (report) view of HTH Survey, DMP and Census data stored in the HDR DB. ARS is deployed in...

  6. Ars Electronica tulekul / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2003-01-01

    6.-11. IX toimub Austrias Linzis "Ars Electronica" festival, mille teema on "Code - The Language of Our Time". Festivali kavast, osalejatest, ava-performance'ist "Europe - A Symphonic Vision", näitusest "Cyberarts 2003. Prix Ars Electronica"

  7. A compilation of {sup 40}Ar-{sup 39} and K-Ar ages: report 25

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, P A [Geological Survey of Canada, Ottawa, ON (Canada); Roddick, J C

    1997-12-31

    Twenty-three {sup 40}Ar-{sup 39}Ar age determinations (including two potassium-argon analyses) carried out by the Geological Survey of Canada are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in outline. An index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference. (author). 6 refs., 2 tabs., 1 fig.

  8. ^<40>Ar-^<39>Ar Age Studies for Tectonics of the Gondwana Land

    OpenAIRE

    Takigami, Yutaka; Sugiura, Naoji

    1997-01-01

    ^Ar-^Ar age studies have been performed for samples from Antarctica and India which were parts of the Gondwana land at Mesozoic and Paleozoic time in order to investigate their thermal history and tectonic movement. From the both areas, ages of about 500 Ma which have been considered to be the age of Pan-African Orogeny were obtained, which represents that this thermal event spread widely over the Gondwana land.

  9. GPS-Based AR Games Development Potential

    Directory of Open Access Journals (Sweden)

    Gregorius Alvin Raditya Santoso

    2014-11-01

    Full Text Available The application of new technologies in a game is not a new thing. One example is the application of Augmented Reality (AR technology in game. Many people do not know the application of AR technology in game, although the application of this technology is able to produce a game with unique gameplay. In addition, since AR game is GPS-based, it offers new gaming experience, that is, playing outdoors in which the real world becomes the game arena. This advantage gives the AR technology a huge potential to be developed into a game

  10. Image Reference Database in Teleradiology: Migrating to WWW

    Science.gov (United States)

    Pasqui, Valdo

    The paper presents a multimedia Image Reference Data Base (IRDB) used in Teleradiology. The application was developed at the University of Florence in the framework of the European Community TELEMED Project. TELEMED overall goals and IRDB requirements are outlined and the resulting architecture is described. IRDB is a multisite database containing radiological images, selected because their scientific interest, and their related information. The architecture consists of a set of IRDB Installations which are accessed from Viewing Stations (VS) located at different medical sites. The interaction between VS and IRDB Installations follows the client-server paradigm and uses an OSI level-7 protocol, named Telemed Communication Language. After reviewing Florence prototype implementation and experimentation, IRDB migration to World Wide Web (WWW) is discussed. A possible scenery to implement IRDB on the basis of WWW model is depicted in order to exploit WWW servers and browsers capabilities. Finally, the advantages of this conversion are outlined.

  11. 40Ar-39Ar age studies for tectonics of the Gondwana land

    International Nuclear Information System (INIS)

    Takigami, Yutaka; Sugiura, Naoji.

    1997-01-01

    40 Ar- 39 Ar age studies have been performed for samples from Antarctica and India which were parts of the Gondwana land at Mesozoic and Paleozoic time in order to investigate their thermal history and tectonic movement. From the both areas, ages of about 500 Ma which have been considered to be the age of Pan-African Orogeny were obtained, which represents that this thermal event spread widely over the Gondwana land. (author)

  12. Apmierinātības ar dzīvi saistība ar laika perspektīvu

    OpenAIRE

    Selga, Toms

    2013-01-01

    Pētījuma mērķis ir noskaidrot vai pastāv saistības starp apmierinātību ar dzīvi un laika perspektīvu. Tika sagaidīts, ka indivīdiem, kam izteiktākas pozitīvās pagātnes un tagadnes hedoniskā laika uztvere, apmierinātības ar dzīvi rezultāti būs augstāki, bet indivīdiem ar negatīvās pagātnes uztveri apmierinātības ar dzīvi rādītāji būs zemāki (Zhang & Howell, 2011). Lai to noskaidrotu, tika izmantota apmierinātības ar dzīvi aptauja (Satisfaction With Life Scale, SWLS, Diener, Emmons, Larsen,...

  13. A test of the 40Ar/39Ar age spectrum technique on some terrestrial materials

    Science.gov (United States)

    Lanphere, M.A.; Brent, Dalrymple G.

    1971-01-01

    40Ar/39Ar age spectra were determined for 10 terrestrial rock and mineral samples whose geologic history is known from independent evidence. The spectra for six mineral and whole rock samples, including biotite, feldspar, hornblende, muscovite, and granodiorite, that have experienced post-crystallization heating did not reveal the age of crystallization in any obvious way. Minima in the spectra, however, give reasonable maximum ages for reheating and high-temperature maxima can be interpreted as minimum crystallization ages. High-temperature ages of microcline and albite that have not been reheated are approximately 10% younger than the known crystallization age. Apparently there are no domains in these feldspars that have retained radiogenic 40Ar quantitatively. Spectra from two diabase samples that contain significant quantities of excess argon might mistakenly be interpreted as spectra from reheated samples and do not give the age of emplacement. The 40Ar/39Ar age spectrum technique may be a potentially valuable tool for the study of geologic areas with complex histories, but the interpretation of age spectra from terrestrial samples seems to be more difficult than suggested by some previous studies. ?? 1971.

  14. 244-AR Vault Interim Stabilization Project Plan

    International Nuclear Information System (INIS)

    LANEY, T.

    2000-01-01

    The 244-AR Vault Facility, constructed between 1966 and 1968, was designed to provide lag storage and treatment for the Plutonium-Uranium Extraction Facility (PUREX) tank farm sludges. Tank farm personnel transferred the waste from the 244-AR Vault Facility to B Plant for recovery of cesium and strontium. B Plant personnel then transferred the treatment residuals back to the tank farms for storage of the sludge and liquids. The last process operations, which transferred waste supporting the cesium/strontium recovery mission, occurred in April 1978. After the final transfer in 1978, the 244-AR facility underwent a cleanout. However, 2,271 L (600 gal) of sludge were left in Tank 004AR from an earlier transfer from Tank 241-AX-104. When the cleanout was completed, the facility was placed in a standby status. The sludge had been transferred to Tank 004AR to support Pacific Northwest National Laboratory [PNNL] vitrification work. Documentation of waste transfers suggests that a portion of the sludge may have been moved from Tank 004AR to Tank 002AR in preparation for transfer back to the AX Tank Farm; however, quantities of the sludge that were moved to Tank 002AR from that transfer must be estimated

  15. Dating method with /sup 39/Ar

    Energy Technology Data Exchange (ETDEWEB)

    Loosli, H H [Bern Univ. (Switzerland). Physikalisches Inst.

    1983-04-01

    The principles of a dating method based on the cosmic-ray-produced radioisotope /sup 39/Ar are given. Technical requirements such as background and standard gas samples and gas proportional counting systems are described. With samples extracted from Greenland ice it can be demonstrated that /sup 39/Ar ages agree with ages obtained by other methods. First results on ocean water samples show that with this isotope valuable information on ocean mixing and circulation can be expected. /sup 39/Ar results on groundwater samples disagree for some aquifers with conventional /sup 14/C ages; possible explanations are discussed, especially underground production of /sup 39/Ar.

  16. 40Ar-39Ar dating of terrestrial and exterrestrial materials. Basalts from the Japan Sea floor, Deccan Plateau and meteorites from Antarctica

    International Nuclear Information System (INIS)

    Kaneoka, Ichiro; Takigami, Yutaka.

    1994-01-01

    Through a series of 40 Ar- 39 Ar dating for terrestrial and exterrestrial samples, the results for basalts from the Japan Sea floor, Deccan Plateau and for meteorites from Antarctica give significant information concerning their formation histories. 40 Ar- 39 Ar ages of basalts from the Japan Sea floor give a constraint that the Japan Sea floor was formed at least 20 Ma. 40 Ar- 39 Ar ages for dyke samples from the Deccan Plateau indicate a possibility for the occurrence of a little younger ages than that of the main plateau formations by a few million years. Meteorites collected from Antarctica show some variable 40 Ar- 39 Ar ages reflecting their different thermal histories. (author)

  17. Energy dependence of the reaction rate constants of Ar+, Ar++ and N2+ ions with Cl2

    International Nuclear Information System (INIS)

    Lukac, P.; Holubcik, L.; Morva, I.; Lindinger, W.

    2002-01-01

    Dry etching processes using low temperature plasmas in Cl 2 and in Cl 2 -noble gas or nitrogen mixtures are common in the manufacture of semiconductor devices, but their chemical mechanisms are often poorly understood. Results are given for the reaction rate constant measurements of Ar + , Ar ++ , N 2 + ions with chlorine as a function of mean relative kinetic energy. The experiments were performed by using the innsbruck flow drift tube (IFDT) apparatus. Measurements were done at various E/N values, where E is the electric field strength and N the buffer gas density in the drift section. The mean relative kinetic energy KE CM between the ions and the neutral chlorine Cl 2 was calculated using the Wanniers formula. It was found that The N 2 + , Ar + and Ar ++ positive ions react with chlorine Cl 2 very fast and the corresponding reaction rate coefficients depend on the mean relative kinetic energy. For the reaction of Ar - with Cl 2 , its reaction coefficient depends also on the buffer gas. It can imply the enhancement of Cl 2 + ions during etching of Si in the Ar/Cl 2 mixtures. (nevyjel)

  18. Support for the Astronomically Calibrated 40Ar/39Ar Age of Fish Canyon Sanidine

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Zeeden, Christian

    2011-01-01

    al. (2008) determined an astronomically calibrated 40Ar/39Ar age of 28.201 0.046 Ma (2), relative to the indirect astronomically tuned Moroccan Melilla Basin Messâdit section. Here, we provide independent verification for the Kuiper, et al. (2008) FCs age using sanidines extracted from the A1 tephra...

  19. Análise automática de citações disponíveis em arquivos XML da SciELO: o periódico "Perspectivas em Ciência da Informação" em números

    Directory of Open Access Journals (Sweden)

    Max Cirino de Mattos

    Full Text Available O artigo demonstra o uso de arquivos eXtensible Markup Language (XML da Scientific Electronic Library Online (SciELO para a criação de uma base de citações do periódico Perspectivas em Ciência da Informação. Demonstra também o uso desta base de citações fornecendo uma visão bibliométrica desse periódico para o período em que os arquivos estavam disponíveis na SciELO: 2006 a 2014, do volume 11 edição 1 ao volume 19 edição 4, incluindo o número especial desse volume. Foram analisados 532 artigos, e os resultados mostraram 387 artigos com 10.266 citações usadas (145 artigos não apresentaram nenhuma citação. O principal objetivo do artigo é destacar a possibilidade de automação da análise bibliométrica a partir da metodologia proposta - e por esse motivo os dados são apresentados sem nenhum tipo de tratamento de desambiguação. São apresentados relatórios similares aos modelos iniciais de Garfield (1972 para o Science Citation Index (SCI: frequências de citações, estatísticas dos periódicos citados e estatísticas dos periódicos citantes. Sugere-se a disponibilização da base de citações, com atualização automática, de forma integrada ao site do periódico, e a aplicação da metodologia para outros periódicos indexados na SciELO

  20. The Agricultural Model Intercomparison and Improvement Project (AgMIP) Town Hall

    Science.gov (United States)

    Ruane, Alex; Rosenzweig, Cynthia; Kyle, Page; Basso, Bruno; Winter, Jonathan; Asseng, Senthold

    2015-01-01

    AgMIP (www.agmip.org) is an international community of climate, crop, livestock, economics, and IT experts working to further the development and application of multi-model, multi-scale, multi-disciplinary agricultural models that can inform policy and decision makers around the world. This meeting will engage the AGU community by providing a brief overview of AgMIP, in particular its new plans for a Coordinated Global and Regional Assessment of climate change impacts on agriculture and food security for AR6. This Town Hall will help identify opportunities for participants to become involved in AgMIP and its 30+ activities.

  1. Microarea dating of mineral and rock. The application of technique by combining 40Ar/39Ar mass spectrometer with laser probe

    International Nuclear Information System (INIS)

    Hu Shiling; Dai Tongmo; Pu Zhiping

    1998-01-01

    The 40 Ar/ 39 Ar dating of probe technique by the continuous laser is successfully applied to determine the ages of microarea samples for mineral and whole rock, including the standard samples from internal and abroad, volcanical rock from westsouthern Antarctica and Green Pissolites of Guizhou. Isochron ages for volcanical rock to be excess or lost argon are accomplished by the whole fused, and for 'green Pisolites' not only by the whole fused, but also by the steps heat. All of which shows the significant geological ages. It would be exhibited the obvious advantage for dating some special samples to make the microarea 40 Ar/ 39 Ar dating technique by laser probe as compare with conventional K-Ar and 40 Ar/ 39 Ar methods

  2. 40Ar/39Ar age of the Rotoiti Breccia and Rotoehu Ash, Okataina Volcanic Complex, New Zealand, and identification of heterogeneously distributed excess 40Ar in supercooled crystals

    DEFF Research Database (Denmark)

    Flude, Stephanie; Storey, Michael

    2016-01-01

    Co-magmatic granitoid clasts erupted as part of the Rotoiti Ignimbrite (Rotoehu Tephra) contain euhedral K-feldspar and biotite crystals that protrude into miarolytic cavities and show textural evidence for growth in super-cooled conditions and are thus interpreted as growing during eruption. 40Ar...... that appear to be largely unaffected by excess 40Ar. This population gives a statistically robust weighted mean age of 47.4 ± 1.5 ka (1σ, n = 13) and an indistinguishable inverse isochron age of 50 ± 3 ka for this historically difficult to date eruption. The weighted mean age is significantly younger than...... previous age estimates of the Rotoiti eruption obtained by K/Ar and 40Ar/39Ar dating of bracketing lavas, but is indistinguishable from recent 14C and (U–Th)/He dates and estimates based on orbital tuning and sedimentation rates constrained by 14C ages....

  3. Global Application of the Assessment of Communication Skills of Paediatric Endocrinology Fellows in the Management of Differences in Sex Development Using the ESPE E-Learning.Org Portal

    DEFF Research Database (Denmark)

    Kranenburg, Laura J C; Reerds, Sam T H; Cools, Martine

    2017-01-01

    endocrinology. Guidelines are created for the assessment of communication between health professionals and individuals with DSD and their parents. METHODS: Paediatric endocrinology fellows worldwide were invited to study two interactive online cases (www.espe-elearning.org) and to describe a best practice...... as a separate key item to better reflect the qualitative differences in the replies and for simplicity of use by evaluators. CONCLUSIONS: E-learning can play an important role in assessing communication skills. A practical tool is provided to assess how information is shared with patients with DSD...

  4. 75 FR 58465 - U.S. Department of State Advisory Committee on Private International Law: Notice of Annual Meeting

    Science.gov (United States)

    2010-09-24

    ... Choice of Court Agreements, the UNCITRAL E-Commerce and Letter of Credit Conventions, and others... Friday. Time permitting, the discussion is expected to focus on developments in a number of areas, e.g...://www.unidroit.org ; http://www.oas.org , and http://www.nccusl.org . We may, by e-mail, supplement...

  5. The ArDM experiment

    CERN Document Server

    Haranczyk, M; Badertscher, A; Boccone, V; Bourgeois, N; Bueno, A; Carmona-Benitez, M C; Chorowski, M; Creus, W; Curioni, A; Daw, E; Degunda, U; Dell'Antone, A; Droge, M; Epprecht, L; Haller, C; Horikawa, S; Kaufmann, L; Kisiel, J; Knecht, L; Laffranchi, M; Lagoda, J; Lazzaro, C; Lightfoot, P; Lozano, J; Lussi, D; Maire, G; Mania, S; Marchionni, A; Mavrokoridis, K; Melgarejo, A; Mijakowski, P; Natterer, G; Navas-Concha, S; Otiougova, P; Piotrowska, A; Polinski, J; de Prado, M; Przewlocki, P; Ravat, S; Regenfus, C; Resnati, F; Robinson, M; Rochet, J; Romero, L; Rondio, E; Rubbia, A; Scotto-Lavina, L; Spooner, N; Viant, T; Trawinski, A; Ulbricht, J; Zalewska, A

    2010-01-01

    The aim of the ArDM project is the development and operation of a one ton double-phase liquid argon detector for direct Dark Matter searches. The detector measures both the scintillation light and the ionization charge from ionizing radiation using two independent readout systems. This paper briefly describes the detector concept and presents preliminary results from the ArDM R&D program, including a 3 l prototype developed to test the charge readout system.

  6. The potential of AR-V7 as a therapeutic target.

    Science.gov (United States)

    Uo, Takuma; Plymate, Stephen R; Sprenger, Cynthia C

    2018-03-01

    The androgen receptor variant AR-V7 is gaining attention as a potential predictive marker for as well as one of the resistance mechanisms to the most current anti-androgen receptor (AR) therapies in castration-resistant prostate cancer (CRPC). Accordingly, development of next-generation drugs that directly or indirectly target AR-V7 signaling is urgently needed. Areas covered: We review proposed mechanisms of drug resistance in relation to AR-V7 status, the mechanisms of generation of AR-V7, and its transcriptome, cistrome, and interactome. Pharmacological agents that interfere with these processes are being developed to counteract pan AR and AR-V7-specific signaling. Also, we address the current status of the preclinical and clinical studies targeting AR-V7 signaling. Expert opinion: AR-V7 is considered a true therapeutic target, however, it remains to be determined if AR-V7 is a principal driver or merely a bystander requiring heterodimerization with co-expressed full-length AR or other variants to drive CRPC progression. While untangling AR-V7 biology, multiple strategies are being developed to counteract drug resistance, including selective blockade of AR-V7 signaling as well as inhibition of pan-AR signaling. Ideally anti-AR therapies will be combined with agents preventing activation and enrichment of AR negative tumor cells that are otherwise depressed by AR activity axis.

  7. Argon defect complexes in low energy Ar irradiated molybdenum

    International Nuclear Information System (INIS)

    Veen, A. van; Buters, W.T.M.; Kolk, G.J. van der; Caspers, L.M.; Armstrong, T.R.

    1982-01-01

    Thermal desorption spectrometry has been used to study the defects created in Mo irradiated along the direction with Ar ions ranging in energy from 0.1 to 2 keV. In addition to monitoring the release of the implanted Ar, additional information has been obtained by decoration of the defects with low energy helium and subsequent monitoring of the helium release. The studies show evidence that the Ar can be trapped in both substitutional sites and in a configuration in which the Ar is associated with vacancies (ArVsub(n), n >= 2). Most of the Ar implanted at high energy is released at approx. equal to 1500 K by thermal vacancy assisted diffusion. Argon trapped closer to the surface is released at lower temperatures via at least three different surface related release mechanisms. Additional results are presented on the interaction of self interstitial atoms (introduced by 100 eV Xe bombardment) with the Ar defects. Substitutional Ar is found to convert to interstitial Ar which seems to be mobile at room temperature. The Ar-vacancy complexes are found to be reduced to substitutional Ar. The results of atomistic calculations of the release mechanisms will also be presented. (orig.)

  8. Experimental system to measure excitation cross-sections by electron impact. Measurements for ArI and ArII

    International Nuclear Information System (INIS)

    Blanco, F.; Sanchez, J.A.; Aguilera, J.A.; Campos, J.

    1989-01-01

    An experimental set-up to measure excitation cross-section of atomic and molecular levels by electron impact based on the optical method is reported. We also present some measurements on the excitation cross-section for ArI 5p'(1/2)0 level, and for simultaneous ionization and excitation of Ar leading to ArII levels belonging to the 3p 4 4p and 3p 4 4d configurations. (Author)

  9. Use of an A.E.I. MS 10 mass spectrometer for 40Ar-39Ar dating

    International Nuclear Information System (INIS)

    Baksi, A.K.

    1979-01-01

    The use of an AEI mass spectrometer for 40 Ar/ 39 Ar dating could, in principle, be problematical due to its limited mass resolution and because of non-linear mass discrimination under certain operating conditions. These possible drawbacks have been investigated and are found to be easy to overcome. Tailing corrections are relatively small and can be applied precisely for 40 Ar/ 39 Ar ratios <= 300. By operating the instrument with a trap current of 50 μA and an ion repeller voltage of +1.0 w.r.t. cage, problems due to non-linear mass discrimination are eliminated. Using the incremental heating technique and total fusion studies on very small subsamples (10-25 mg.), the homogeneity of some well-known inter-laboratory standards has been investigated; the relative merits of these standards are discussed. (K.B.)

  10. Biofertilización de café orgánico en etapa de vivero en Chiapas, México Biofertilizer of organic coffee in stage of seedlings in Chiapas, Mexico

    OpenAIRE

    María de Lourdes Adriano Anaya; Ramón Jarquín Gálvez; Carlos Hernández Ramos; Miguel Salvador Figueroa; Clara Teresa Monreal Vargas

    2011-01-01

    En Chiapas, la producción de plántulas de café, se realiza convencionalmente con la aplicación de fertilizantes químicos. La producción de café orgánico, requiere la nutrición de plántulas con biofertilizantes y por ello el objetivo fue evaluar el efecto de algunos de éstos en el desarrollo de plántulas de café (Coffe arábica) variedad Bourbon en vivero. El experimento se realizó durante 2007 y 2008 en Cacahohatan,Chiapas. Los inoculantes fueron una cepa Glomus intraradices Schenck y Smith, c...

  11. MEIS1 functions as a potential AR negative regulator

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Liang [Department of Urology, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China); Department of Urology, Civil Aviation General Hospital/Civil Aviation Medical College of Peking University, Beijing 100123 (China); Li, Mingyang [Department of Gastroenterology, Nan Lou Division, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China); Feng, Fan [Department of Pharmacy, General Hospital of Shenyang Military Command, Shenyang 110016 (China); Yang, Yutao [Beijing Institute for Neuroscience, Capital Medical University, Beijing 100069 (China); Hang, Xingyi [National Scientific Data Sharing Platform for Population and Health, Beijing 100730 (China); Cui, Jiajun, E-mail: cuijn@ucmail.uc.edu [Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 (United States); Gao, Jiangping, E-mail: jpgao@163.com [Department of Urology, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China)

    2014-10-15

    The androgen receptor (AR) plays critical roles in human prostate carcinoma progression and transformation. However, the activation of AR is regulated by co-regulators. MEIS1 protein, the homeodomain transcription factor, exhibited a decreased level in poor-prognosis prostate tumors. In this study, we investigated a potential interaction between MEIS1 and AR. We found that overexpression of MEIS1 inhibited the AR transcriptional activity and reduced the expression of AR target gene. A potential protein–protein interaction between AR and MEIS1 was identified by the immunoprecipitation and GST pull-down assays. Furthermore, MEIS1 modulated AR cytoplasm/nucleus translocation and the recruitment to androgen response element in prostate specific antigen (PSA) gene promoter sequences. In addition, MEIS1 promoted the recruitment of NCoR and SMRT in the presence of R1881. Finally, MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells. Taken together, our data suggests that MEIS1 functions as a novel AR co-repressor. - Highlights: • A potential interaction was identified between MEIS1 and AR signaling. • Overexpression of MEIS1 reduced the expression of AR target gene. • MEIS1 modulated AR cytoplasm/nucleus translocation. • MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells.

  12. MEIS1 functions as a potential AR negative regulator

    International Nuclear Information System (INIS)

    Cui, Liang; Li, Mingyang; Feng, Fan; Yang, Yutao; Hang, Xingyi; Cui, Jiajun; Gao, Jiangping

    2014-01-01

    The androgen receptor (AR) plays critical roles in human prostate carcinoma progression and transformation. However, the activation of AR is regulated by co-regulators. MEIS1 protein, the homeodomain transcription factor, exhibited a decreased level in poor-prognosis prostate tumors. In this study, we investigated a potential interaction between MEIS1 and AR. We found that overexpression of MEIS1 inhibited the AR transcriptional activity and reduced the expression of AR target gene. A potential protein–protein interaction between AR and MEIS1 was identified by the immunoprecipitation and GST pull-down assays. Furthermore, MEIS1 modulated AR cytoplasm/nucleus translocation and the recruitment to androgen response element in prostate specific antigen (PSA) gene promoter sequences. In addition, MEIS1 promoted the recruitment of NCoR and SMRT in the presence of R1881. Finally, MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells. Taken together, our data suggests that MEIS1 functions as a novel AR co-repressor. - Highlights: • A potential interaction was identified between MEIS1 and AR signaling. • Overexpression of MEIS1 reduced the expression of AR target gene. • MEIS1 modulated AR cytoplasm/nucleus translocation. • MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells

  13. Microbiologia do ar : monitorização do ar em ambiente hospitalar

    OpenAIRE

    Santos, Ana Carina Marques dos

    2008-01-01

    O complexo ambiente hospitalar requer atenção especial, para assegurar uma saudável qualidade do ar interior, protegendo assim os profissionais de saúde e utentes de infecções nosocomiais e de doenças ocupacionais. Embora seja amplamente reconhecido que a contaminação de um bloco operatório seja a principal responsável pela complicação de uma cirurgia, em Portugal, estudos sobre microbiologia do ar a nível hospitalar são escassos. O objectivo deste estudo é investigar a vari...

  14. Progress on using deuteron-deuteron fusion generated neutrons for 40Ar/39Ar sample irradiation

    Science.gov (United States)

    Rutte, Daniel; Renne, Paul R.; Becker, Tim; Waltz, Cory; Ayllon Unzueta, Mauricio; Zimmerman, Susan; Hidy, Alan; Finkel, Robert; Bauer, Joseph D.; Bernstein, Lee; van Bibber, Karl

    2017-04-01

    We present progress on the development and proof of concept of a deuteron-deuteron fusion based neutron generator for 40Ar/39Ar sample irradiation. Irradiation with deuteron-deuteron fusion neutrons is anticipated to reduce Ar recoil and Ar production from interfering reactions. This will allow dating of smaller grains and increase accuracy and precision of the method. The instrument currently achieves neutron fluxes of ˜9×107 cm-2s-1 as determined by irradiation of indium foils and use of the activation reaction 115In(n,n')115mIn. Multiple foils and simulations were used to determine flux gradients in the sample chamber. A first experiment quantifying the loss of 39Ar is underway and will likely be available at the time of the presentation of this abstract. In ancillary experiments via irradiation of K salts and subsequent mass spectrometric analysis we determined the cross-sections of the 39K(n,p)39Ar reaction at ˜2.8 MeV to be 160 ± 35 mb (1σ). This result is in good agreement with bracketing cross-section data of ˜96 mb at ˜2.45 MeV and ˜270 mb at ˜4 MeV [Johnson et al., 1967; Dixon and Aitken, 1961 and Bass et al. 1964]. Our data disfavor a much lower value of ˜45 mb at 2.59 MeV [Lindström & Neuer, 1958]. In another ancillary experiment the cross section for 39K(n,α)36Cl at ˜2.8 MeV was determined as 11.7 ± 0.5 mb (1σ), which is significant for 40Ar/39Ar geochronology due to subsequent decay to 36Ar as well as for the determination of production rates of cosmogenic 36Cl. Additional experiments resolving the cross section functions on 39K between 1.5 and 3.6 MeV are on their way using the LICORNE neutron source of the IPN Orsay tandem accelerator. Results will likely be available at the time of the presentation of this abstract. While the neutron generator is designed for fluxes of ˜109 cm-2s-1, arcing in the sample chamber currently limits the power—straightforwardly correlated to the neutron flux—the generator can safely be run at. Further

  15. Garantia da qualidade no processamento de alimentos orgânicos

    Directory of Open Access Journals (Sweden)

    Elga Batista da Silva

    2014-05-01

    Full Text Available Os produtos orgânicos devem seguir normas específicas para que sejam assim classificados. O objetivo desse trabalho foi discutir aspectos fundamentais para a garantia da qualidade de produtos orgânicos processados. A elaboração de produtos orgânicos processados envolve várias dificuldades tecnológicas e legais, relacionadas a aspectos como proibição de aditivos em geral, busca pela certificação e riscos de contaminação cruzada com resíduos de matérias primas não orgânicas. Apesar dessas dificuldades, vantagens podem como a obtenção de alimentos com menor risco de acarretar efeitos deletérios à saúde (como câncer e alergias, preservação de ecossistemas e teores expressivos de nutrientes pode ser obtidas. Também é importante atestar que alimentos orgânicos industrializados sejam realmente isentos de resíduos de matérias primas convencionais a partir de análises sensíveis o bastante para essa finalidade. Conclui-se que o processamento industrial de orgânicos é uma área promissora, pois possibilita a elaboração de produtos alimentícios com diversos benefícios, de ordens nutricional e ambiental.

  16. Ar + NO microwave plasmas for Escherichia coli sterilization

    International Nuclear Information System (INIS)

    Hueso, Jose L; Rico, Victor J; Cotrino, Jose; Gonzalez-Elipe, Agustin R; Frias, Jose E

    2008-01-01

    Ar + NO microwave discharges are used for sterilization and the results are compared with additional experiments with Ar, O 2 and N 2 -O 2 plasma mixtures. The NO * species produced in the Ar-NO mixtures remain up to long distances from the source, thus improving the sterilization efficiency of the process. E. coli individuals exposed to the Ar + NO plasma undergo morphological damage and cell lysis. Combined effects of etching (by O * and Ar * species) and UV radiation (from deactivation of NO * species) are responsible for the higher activity found for this plasma mixture. (fast track communication)

  17. Tibetan tectonics from 40Ar/39Ar analysis of a single K-feldspar sample

    International Nuclear Information System (INIS)

    Richter, F.M.; Lovera, O.M.; Harrison, T.M.; Copeland, P.

    1991-01-01

    40 Ar/ 39 Ar data on an alkali feldspar sample from the Quxu pluton, Gangdese batholith, southern Tibet, allow a detailed assessment of unroofing and uplift history between 35 and 18 Ma. The 39 Ar Arrhenius plot for this sample shows departures from a linear relationship between the effective diffusion parameter, log(D/r 2 ), and reciprocal temperature, which we interpret to be the result of a distribution of distinct diffusion-domain sizes. We use an alternative way of plotting the Arrhenius data that exhibits domain size versus cumulative % 39 Ar released during step heating. The 40 Ar/ 39 Ar age spectrum of the sample has features, such as local age plateaus, that are most easily explained in terms of the distinctive closure age of particular domains. The fact that the same distribution of diffusion-domain sizes explains both the Arrhenius data and the age spectrum is an indication that the diffusion properties operating in the laboratory are those of the sample while it was in its natural environment. Modelling of the age spectrum with a distribution of domain sizes results in the recovery of a continuous cooling-history segment rather than a single time-temperature datum. We demonstrate the robustness of the cooling-curve determination by showing the large misfits to the age spectrum that arise from relatively small changes in the cooling history. The best-fit cooling curve for the Quxu sample shows a decreasing rate of cooling in the time interval 35-18 Ma, followed by a very rapid cooling beginning at about 18 Ma. We have used a thermal model for the conductive cooling of an unroofing pluton to estimate the rate of unroofing required to explain the Quxu cooling curve, and find that in the 35-20 Ma time interval, the primary control of the thermal evolution is the conductive loss of magmatic heat with little or no unroofing (unroofing rates of approximately 0.05 mm/yr) followed by a brief period (<5 Ma) of very rapid unroofing with rates of order 2 mm

  18. In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells.

    Science.gov (United States)

    El-Heliebi, Amin; Hille, Claudia; Laxman, Navya; Svedlund, Jessica; Haudum, Christoph; Ercan, Erkan; Kroneis, Thomas; Chen, Shukun; Smolle, Maria; Rossmann, Christopher; Krzywkowski, Tomasz; Ahlford, Annika; Darai, Evangelia; von Amsberg, Gunhild; Alsdorf, Winfried; König, Frank; Löhr, Matthias; de Kruijff, Inge; Riethdorf, Sabine; Gorges, Tobias M; Pantel, Klaus; Bauernhofer, Thomas; Nilsson, Mats; Sedlmayr, Peter

    2018-03-01

    Liquid biopsies can be used in castration-resistant prostate cancer (CRPC) to detect androgen receptor splice variant 7 (AR-V7), a splicing product of the androgen receptor. Patients with AR-V7-positive circulating tumor cells (CTCs) have greater benefit of taxane chemotherapy compared with novel hormonal therapies, indicating a treatment-selection biomarker. Likewise, in those with pancreatic cancer (PaCa), KRAS mutations act as prognostic biomarkers. Thus, there is an urgent need for technology investigating the expression and mutation status of CTCs. Here, we report an approach that adds AR-V7 or KRAS status to CTC enumeration, compatible with multiple CTC-isolation platforms. We studied 3 independent CTC-isolation devices (CellCollector, Parsortix, CellSearch) for the evaluation of AR-V7 or KRAS status of CTCs with in situ padlock probe technology. Padlock probes allow highly specific detection and visualization of transcripts on a cellular level. We applied padlock probes for detecting AR-V7, androgen receptor full length (AR-FL), and prostate-specific antigen (PSA) in CRPC and KRAS wild-type (wt) and mutant (mut) transcripts in PaCa in CTCs from 46 patients. In situ analysis showed that 71% (22 of 31) of CRPC patients had detectable AR-V7 expression ranging from low to high expression [1-76 rolling circle products (RCPs)/CTC]. In PaCa patients, 40% (6 of 15) had KRAS mut expressing CTCs with 1 to 8 RCPs/CTC. In situ padlock probe analysis revealed CTCs with no detectable cytokeratin expression but positivity for AR-V7 or KRAS mut transcripts. Padlock probe technology enables quantification of AR-V7, AR-FL, PSA, and KRAS mut/wt transcripts in CTCs. The technology is easily applicable in routine laboratories and compatible with multiple CTC-isolation devices. © 2017 American Association for Clinical Chemistry.

  19. Producción orgánica para una alimentación sana

    OpenAIRE

    Evangelina Méndez

    2016-01-01

    El presente trabajo se relaciona con la importancia del uso de fertilizantes o abonos orgánicos, como base para la producción de alimentos orgánicos, que incluye pruebas de laboratorio y la instrumentalización de encuestas a los grupos objetivos de insumos y productos orgánicos. Este artículo tiene como propósito dar a conocer los beneficios nutritivos de los productos orgánicos. El cuidado del medio ambiente y el interés por una alimentación sana han dado lugar al uso de fertilizantes orgáni...

  20. Páginas de colectivos LGBT portugueses

    Directory of Open Access Journals (Sweden)

    Ana Cristina Santos

    2012-10-01

    Full Text Available Associação Cultural Janela Indiscreta: http://www.lisbonfilmfest.org/ AT – Associação para o Estudo e Defesa dos Direitos à Identidade de Género: http://a-trans.planetaclix.pt/ Clube Safo: http://www.clubesafo.com/ ILGA Portugal: http://ilga-portugal.oninet.pt/ não te prives – Grupo de Defesa dos Direitos Sexuais: http://www.naoteprives.org/ Opus Gay: http://www.opusgay.org/ Panteras Rosa – Frente de Combate à LesBiGayTransfobia: http://www.panterasrosa.com/ Ponto Bi: http://www.pontobi....

  1. Analitiki iz Kreml.org / Gennadi Muravin

    Index Scriptorium Estoniae

    Muravin, Gennadi

    2003-01-01

    Internetileheküljel Kreml.org, kus ilmunud materjalide sisu vihjab nende päritolule presidendi- ja valitsusringkondadest, ilmub sageli materjale, mida võib lugeda ebasõbralikeks teiste riikide suhtes. Väljavõtteid tekstidest

  2. Selfsurvey.org

    DEFF Research Database (Denmark)

    Winkler, Till J.; Sarstedt, Marko; Keil, Marian

    2015-01-01

    research model and a structural equation model-based prediction technique. Based on the partial least squares analysis results of a training dataset, selfsurvey employs a scoring algorithm to derive respondent-specific predicted scores, compares these with the observed scores, and provides visualized......This design research builds on the idea to combine the strengths of traditional survey research with a more practice-oriented benchmarking approach. We present selfsurvey.org, an online survey platform that allows providing instant and respondent-specific feedback based on a scientifically grounded...... and text-based outputs. Our evaluation of selfsurvey in the context of a maturity benchmarking study provides an indication for the perceived usefulness of this artifact and its underlying scoring algorithm. We argue that this prediction-based approach, which goes far beyond the functionality of common...

  3. CHOgenome.org 2.0: Genome resources and website updates.

    Science.gov (United States)

    Kremkow, Benjamin G; Baik, Jong Youn; MacDonald, Madolyn L; Lee, Kelvin H

    2015-07-01

    Chinese hamster ovary (CHO) cells are a major host cell line for the production of therapeutic proteins, and CHO cell and Chinese hamster (CH) genomes have recently been sequenced using next-generation sequencing methods. CHOgenome.org was launched in 2011 (version 1.0) to serve as a database repository and to provide bioinformatics tools for the CHO community. CHOgenome.org (version 1.0) maintained GenBank CHO-K1 genome data, identified CHO-omics literature, and provided a CHO-specific BLAST service. Recent major updates to CHOgenome.org (version 2.0) include new sequence and annotation databases for both CHO and CH genomes, a more user-friendly website, and new research tools, including a proteome browser and a genome viewer. CHO cell-line specific sequences and annotations facilitate cell line development opportunities, several of which are discussed. Moving forward, CHOgenome.org will host the increasing amount of CHO-omics data and continue to make useful bioinformatics tools available to the CHO community. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Ar + NO microwave plasmas for Escherichia coli sterilization

    Energy Technology Data Exchange (ETDEWEB)

    Hueso, Jose L; Rico, Victor J; Cotrino, Jose; Gonzalez-Elipe, Agustin R [Instituto de Ciencia de Materiales de Sevilla, Centro Mixto CSIC-Universidad de Sevilla, Centro de Investigaciones Cientificas Isla de la Cartuja, Avda. Americo Vespucio 49, 41092 Sevilla (Spain); Frias, Jose E [Instituto de BioquImica Vegetal y FotosIntesis (IBVF-CSIC). Centro de Investigaciones CientIficas Isla de la Cartuja. Avda Americo Vespucio, 49, 41092 Sevilla (Spain)], E-mail: jhueso@icmse.csic.es

    2008-05-07

    Ar + NO microwave discharges are used for sterilization and the results are compared with additional experiments with Ar, O{sub 2} and N{sub 2}-O{sub 2} plasma mixtures. The NO{sup *} species produced in the Ar-NO mixtures remain up to long distances from the source, thus improving the sterilization efficiency of the process. E. coli individuals exposed to the Ar + NO plasma undergo morphological damage and cell lysis. Combined effects of etching (by O{sup *} and Ar{sup *} species) and UV radiation (from deactivation of NO{sup *} species) are responsible for the higher activity found for this plasma mixture. (fast track communication)

  5. Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells.

    Science.gov (United States)

    Thomas-Jardin, Shayna E; Kanchwala, Mohammed S; Jacob, Joan; Merchant, Sana; Meade, Rachel K; Gahnim, Nagham M; Nawas, Afshan F; Xing, Chao; Delk, Nikki A

    2018-06-01

    In immunosurveillance, bone-derived immune cells infiltrate the tumor and secrete inflammatory cytokines to destroy cancer cells. However, cancer cells have evolved mechanisms to usurp inflammatory cytokines to promote tumor progression. In particular, the inflammatory cytokine, interleukin-1 (IL-1), is elevated in prostate cancer (PCa) patient tissue and serum, and promotes PCa bone metastasis. IL-1 also represses androgen receptor (AR) accumulation and activity in PCa cells, yet the cells remain viable and tumorigenic; suggesting that IL-1 may also contribute to AR-targeted therapy resistance. Furthermore, IL-1 and AR protein levels negatively correlate in PCa tumor cells. Taken together, we hypothesize that IL-1 reprograms AR positive (AR + ) PCa cells into AR negative (AR - ) PCa cells that co-opt IL-1 signaling to ensure AR-independent survival and tumor progression in the inflammatory tumor microenvironment. LNCaP and PC3 PCa cells were treated with IL-1β or HS-5 bone marrow stromal cell (BMSC) conditioned medium and analyzed by RNA sequencing and RT-QPCR. To verify genes identified by RNA sequencing, LNCaP, MDA-PCa-2b, PC3, and DU145 PCa cell lines were treated with the IL-1 family members, IL-1α or IL-1β, or exposed to HS-5 BMSC in the presence or absence of Interleukin-1 Receptor Antagonist (IL-1RA). Treated cells were analyzed by western blot and/or RT-QPCR. Comparative analysis of sequencing data from the AR + LNCaP PCa cell line versus the AR - PC3 PCa cell line reveals an IL-1-conferred gene suite in LNCaP cells that is constitutive in PC3 cells. Bioinformatics analysis of the IL-1 regulated gene suite revealed that inflammatory and immune response pathways are primarily elicited; likely facilitating PCa cell survival and tumorigenicity in an inflammatory tumor microenvironment. Our data supports that IL-1 reprograms AR + PCa cells to mimic AR - PCa gene expression patterns that favor AR-targeted treatment resistance and cell survival. © 2018 Wiley

  6. 75 FR 12165 - Class E Airspace; Batesville, AR

    Science.gov (United States)

    2010-03-15

    ...-1177; Airspace Docket No. 09-ASW-34] Class E Airspace; Batesville, AR AGENCY: Federal Aviation... Class E airspace at Batesville, AR. Decommissioning of the Independence County non-directional beacon... for standard instrument approach procedures at Batesville Regional Airport, Batesville, AR. Airspace...

  7. 37Ar monitoring techniques and on-site inspection system

    International Nuclear Information System (INIS)

    Duan Rongliang; Chen Yinliang; Li Wei; Wang Hongxia; Hao Fanhua

    2001-01-01

    37 Ar is separated, purified and extracted from air sample with a low temperature gas-solid chromatographic purifying method, prepared into a radioactive measurement source and its radioactivity is measured with a proportional counter. Based on the monitoring result, a judgement can be made if an nuclear explosion event has happened recently in a spectabilis area. A series of element techniques that are associated the monitoring of the trace element 37 Ar have been investigated and developed. Those techniques include leaked gas sampling, 37 Ar separation and purification, 37 Ar radioactivity measurement and the on-site inspection of 37 Ar. An advanced 37 Ar monitoring method has been developed, with which 200 liters of air can be treated in 2 hours with sensitivity of 0.01 Bq/L for 37 Ar radioactivity measurement. A practical 37 Ar On-site Inspection system has been developed. This research work may provide technical and equipment support for the verification protection, verification supervision and CTBT verification

  8. Formation of doubly charged argon ions, Ar2+, from long-lived highly excited argon ions, Arsup(+*), colliding with Ar and N2 gases

    International Nuclear Information System (INIS)

    Okuno, Kazuhiko

    1976-01-01

    Formation of Ar 2+ from long-lived highly excited Ar + * colliding with Ar and N 2 gases is studied by means of a tandem mass spectrometer. The tandem mass spectrometer used consists of two mass analyzers connected in series and a collision chamber located in between. The collision chamber is electrically floated and can be set at a desired potential, so that one can identify the fast ions (resulting from the primary ions) and the slow ions (secondary ions) in the mass spectra taken by the second mass analyzer. When the first mass analyzer is tuned to Ar + , peaks corresponding Ar 2+ appear in the second mass spectra. From the analysis of variation of mass positions and heights of these peaks with the change of the potential and pressure of the collision chamber, the Ar 2+ is concluded to result from the primary Ar + in collision with gas molecules and wall surface. From the threshold behavior of the product Ar 2+ with the electron energy in the ion source, three sets of long-lived highly excited Ar + * states (Rydberg states) are found to be responsible for this process. They are 3s 2 3p 4 ( 3 P)nl, 3s 2 3p 4 ( 1 D 2 )n'l and 3s 2 3p 4 ( 1 S 0 )n''l converging to Ar 2+3 Psub(2.1.0) (43.38, 43.51, 43.57 eV), 1 D 2 (45.11 eV) and 1 S 0 (47.50 eV), respectively. Their fractional ratio in the primary Ar + beam is determined as 3.0:1.0:1.2 which is close to that of multiplicities of the states concerned. The autoionization mechanism reported by other investigators to be responsible for the formation of Ar 2+ in Aston band or tandem mass spectra is found to be negligible. The cross sections of formation of Ar 2+ from Ar + * colliding with Ar and N 2 increase in proportion to the 1.15th power of the collision energy in the range from 750 eV to 2.5 keV. At the collision energy of 1.0 keV, they are 2.0x10 -20 /F cm 2 for Ar target and 6.6x10 -20 /F cm 2 for N 2 target, where the fractional density of Ar + * is estimated to be 0.7x10 -4 -4 . (auth.)

  9. I-Xe and 40Ar-39Ar analyses of silicate from the Eagle Station pallasite and the anomalous iron meteorite Enon

    International Nuclear Information System (INIS)

    Niemeyer, S.

    1983-01-01

    Silicate from two unusual iron-rich meteorites were analyzed by the I-Xe and 40 Ar- 39 Ar techniques. Enon, an anomalous iron meteorite with chondritic silicate, shows no loss of radiogenic 40 Ar at low temperature, and gives a plateau age of 4.59 +- 0.03 Ga. Although the Xe data fail to define an I-Xe correlation the inferred Pu/U ratio is more than 2 σ above the chondritic value, and the Pu abundance derived from the concentration of Pu-fission Xe is 6 times greater than the abundance inferred for CI meteorites. These findings for Enon, coupled with data for IAB iron meteorites, suggest that presence of chondritic silicate in an iron-rich meteorite is diagnostic of an old radiometric age with little subsequent thermal disturbance. The Eagle Station pallasite, the most 16 O-rich meteorite known, gives a complex 40 Ar- 39 Ar age pattern which suggests a recent severe thermal disturbance. The absence of excess 129 Xe, and the low trapped Ar and Xe contents, are consistent with this interpretation. The similarity between 40 Ar- 39 Ar data for Eagle Station and for the olivine-rich meteorite Chassigny lends credence to the previous suggestion of a connection between Chassigny and pallasites. (author)

  10. Near thermal charge transfer between Ar+2 and N2

    International Nuclear Information System (INIS)

    Holzscheiter, H.M.; Church, D.A.

    1981-01-01

    The near thermal charge transfer reaction of Ar +2 with N 2 has been studied at total pressures below 10 -7 Torr using a stored ion technique. Ar +2 ions produced by electron impact double ionization of Ar gas were selectively stored for times the order of seconds in a split-ring Penning-type ion trap. The decay with time of the initial ion sample number in a mixture of Ar and N 2 gases was fit to the sum of two exponentials, corresponding to different reaction rates for the 3 P and 1 D low-lying Ar +2 levels. The observed Ar +2 number decrease is attributed to the double-charge transfer process Ar +2 +N 2 →Ar+N 2 +2 →Ar+N + +N + in accord with recent flow-tube measurements. A rate constant for the metastable Ar +2 ( 1 D) level reaction with a value k( 1 D)=1.4 x 10 -9 cm 3 /sec is obtained, using the previously measured rate constant for the Ar +2 ( 3 P) state

  11. Laser-fusion 40Ar/39Ar Ages of Darwin Impact Glass

    Science.gov (United States)

    Lo, Ching-Hua; Howard, Kieren T.; Chung, Sun-Lin; Meffre, Sebastien

    2002-11-01

    Three samples of Darwin Glass, an impact glass found in Tasmania, Australia at the edge of the Australasian tektite strewn field were dated using the 40Ar/39Ar single-grain laser fusion technique, yielding isochron ages of 796-815 ka with an overall weighted mean of 816 ± 7 ka. These data are statistically indistinguishable from those recently reported for the Australasian tektites from Southeast Asia and Australia (761-816 ka; with a mean weighted age of 803 ± 3 ka). However, considering the compositional and textural differences and the disparity from the presumed impact crater area for Australasian tektites, Darwin Glass is more likely to have resulted from a distinct impact during the same period of time.

  12. Ar-37 in the Atmospheric and Sub-Soil Gases

    International Nuclear Information System (INIS)

    Purtschert, R.; Raghoo, L.S.

    2015-01-01

    On-site inspection of the radioactive noble gas isotope 37Ar is a definitive and unambiguous indicator of an underground nuclear explosion. 37Ar is produced underground by neutron activation of calcium by the reaction 40Ca(n,α)37Ar. In the atmosphere, 37Ar is produced by the spallation reaction 40Ar(n,4n)37Ar. Periodic measurements over the last six years on air collected in Bern revealed a background level in the order of 1-5 mBq/m 3 air in agreement with former findings and theoretical calculations. Those calculations also indicated that the intrusion of stratospheric air masses may lead to elevated tropospheric 37Ar concentrations up to 8-10 mBq/m 3 air. Selected samples taken up to now in the vicinity of nuclear power plants revealed no significant deviation from the natural background. In order to distinguish between natural and artificially elevated 37Ar the location-specific 37Ar activity range in soils, rocks and the atmosphere were identified. From CARIBIC flights, a passenger aircraft with a special air freight container filled with scientific equipment in the cargo compartment, tropospheric air samples were analyzed for 37Ar and 85Kr. The natural 37Ar production in soils and the rock basement underlying the alluvium is investigated by means of in situ measurements of different isotopes, theoretical calculations and irradiation experiments on selected rock samples. This will help resolve the temporal evolution and/or constancy of the natural 37Ar background and allow for an interpretation in terms of the identification of clandestine nuclear explosions. (author)

  13. Design guidelines for teaching about design guidelines for educational WWW-sites

    NARCIS (Netherlands)

    Collis, Betty; Winnips, Koos; Ottmann, Thomas; Tomek, Ivan

    1998-01-01

    This paper describes how the authors use a mixture of World Wide Web (WWW)-based functionalities and new didactics to teach educational technology students at the University of Twente (Netherlands) about the design of WWW-based learning environments. Topics discussed include: (1) the content of

  14. Targeting AR Variant-Coactivator Interactions to Exploit Prostate Cancer Vulnerabilities.

    Science.gov (United States)

    Magani, Fiorella; Peacock, Stephanie O; Rice, Meghan A; Martinez, Maria J; Greene, Ann M; Magani, Pablo S; Lyles, Rolando; Weitz, Jonathan R; Burnstein, Kerry L

    2017-11-01

    Castration-resistant prostate cancer (CRPC) progresses rapidly and is incurable. Constitutively active androgen receptor splice variants (AR-Vs) represent a well-established mechanism of therapeutic resistance and disease progression. These variants lack the AR ligand-binding domain and, as such, are not inhibited by androgen deprivation therapy (ADT), which is the standard systemic approach for advanced prostate cancer. Signaling by AR-Vs, including the clinically relevant AR-V7, is augmented by Vav3, an established AR coactivator in CRPC. Using mutational and biochemical studies, we demonstrated that the Vav3 Diffuse B-cell lymphoma homology (DH) domain interacted with the N-terminal region of AR-V7 (and full length AR). Expression of the Vav3 DH domain disrupted Vav3 interaction with and enhancement of AR-V7 activity. The Vav3 DH domain also disrupted AR-V7 interaction with other AR coactivators: Src1 and Vav2, which are overexpressed in PC. This Vav3 domain was used in proof-of-concept studies to evaluate the effects of disrupting the interaction between AR-V7 and its coactivators on CRPC cells. This disruption decreased CRPC cell proliferation and anchorage-independent growth, caused increased apoptosis, decreased migration, and resulted in the acquisition of morphological changes associated with a less aggressive phenotype. While disrupting the interaction between FL-AR and its coactivators decreased N-C terminal interaction, disrupting the interaction of AR-V7 with its coactivators decreased AR-V7 nuclear levels. Implications: This study demonstrates the potential therapeutic utility of inhibiting constitutively active AR-V signaling by disrupting coactivator binding. Such an approach is significant, as AR-Vs are emerging as important drivers of CRPC that are particularly recalcitrant to current therapies. Mol Cancer Res; 15(11); 1469-80. ©2017 AACR . ©2017 American Association for Cancer Research.

  15. 40Ar/39Ar geochronology at the Instituto de Geociências, USP: instrumentation, analytical procedures, and calibration

    Directory of Open Access Journals (Sweden)

    PAULO M. VASCONCELOS

    2002-06-01

    Full Text Available Laser heating 40Ar/39Ar geochronology provides high analytical precision and accuracy, mum-scale spatial resolution, and statistically significant data sets for the study of geological and planetary processes. A newly commissioned 40Ar/39Ar laboratory at CPGeo/USP, São Paulo, Brazil, equips the Brazilian scientific community with a new powerful tool applicable to the study of geological and cosmochemical processes. Detailed information about laboratory layout, environmental conditions, and instrumentation provides the necessary parameters for the evaluation of the CPGeo/USP 40Ar/39Ar suitability to a diverse range of applications. Details about analytical procedures, including mineral separation, irradiation at the IPEN/CNEN reactor at USP, and mass spectrometric analysis enable potential researchers to design the necessary sampling and sample preparation program suitable to the objectives of their study. Finally, the results of calibration tests using Ca and K salts and glasses, international mineral standards, and in-house mineral standards show that the accuracy and precision obtained at the 40Ar/39Ar laboratory at CPGeo/USP are comparable to results obtained in the most respected laboratories internationally. The extensive calibration and standardization procedures undertaken ensure that the results of analytical studies carried out in our laboratories will gain immediate international credibility, enabling Brazilian students and scientists to conduct forefront research in earth and planetary sciences.A geocronologia de 40Ar/39Ar por aquecimento a laser permite alta precisão e acurácia analítica, tem resolução espacial em escala micrométrica, e fornece um número de dados estatisticamente significantes para o estudo de processos geológicos e planetários. Um recém construído laboratório de 40Ar/39Ar no CPGeo/USP, São Paulo, Brazil, mune a sociedade científica brasileira com uma técnica eficaz aplicável aos estudos geol

  16. 75 FR 12162 - Class E Airspace; Manila, AR

    Science.gov (United States)

    2010-03-15

    ...-1184; Airspace Docket No. 09-ASW-39] Class E Airspace; Manila, AR AGENCY: Federal Aviation... Class E airspace at Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila... instrument approach procedures at Manila Municipal Airport, Manila, AR. Airspace reconfiguration is necessary...

  17. Producción orgánica para una alimentación sana

    Directory of Open Access Journals (Sweden)

    Evangelina Méndez

    2016-06-01

    Full Text Available El presente trabajo se relaciona con la importancia del uso de fertilizantes o abonos orgánicos, como base para la producción de alimentos orgánicos, que incluye pruebas de laboratorio y la instrumentalización de encuestas a los grupos objetivos de insumos y productos orgánicos. Este artículo tiene como propósito dar a conocer los beneficios nutritivos de los productos orgánicos. El cuidado del medio ambiente y el interés por una alimentación sana han dado lugar al uso de fertilizantes orgánicos en cultivos, facilitando la producción de alimentos frescos y sanos, libres de sustancias tóxicas conocidos como alimentos orgánicos. Durante las actividades del proyecto de investigación IC-ULVRG12-10 "GUIA PARA EXPORTAR ABONO ORGANICO HACIA LOS PRINCIPALES MERCADOS DE ESTADOS UNIDOS, EUROPA y SUDAMERICA" la muestra encuestada demostró que no se encuentra lo suficientemente concientizada sobre el uso y beneficio de los productos orgánicos, sin embargo existe interés por parte del consumidor al consultar directamente en el lugar de compra sobre los mismos, especialmente los vegetales. Durante la investigación experimental las pruebas de laboratorio confirman el alto valor nutricional que aportan los abonos orgánicos al suelo y a las plantas.

  18. Effects of lamellae size distributions from 40Ar/39Ar on sedimentary thermo-chronology in the San Joaquin Basin

    International Nuclear Information System (INIS)

    Jepsen, A.-M.; Lerche, I.; Thomsen, R.O.

    1990-01-01

    A model description is provided for the release of 40 Ar/ 39 Ar from detrital microclines which specifically includes the effects of grain size distributions, thus allowing smaller grains to release argon faster than the more retentive larger grains. The model also includes the effects of sedimentary thermal history after burial influencing the pre-depositional 40 Ar/ 30 Ar ratio. Application of the model to the measured age spectra from six depths in the Tejon Block and four in the Basin Block of the San Joaquin Basin demonstrates that the grain size distribution effect plays a major role in masking the extraction of thermal history information from the observed age spectra. In addition, the grain size effect is not systematic with depth, and other competing effects, such as isotopic fractionation of diffusion coefficients, multi-provenance depositional supply, and variable concentrations of 40 Ar and 39 K per microcline at burial deposition time, make the extraction of thermal history information even more difficult. (author)

  19. Timing of Secondary Hydrothermal Alteration of the Luobusa Chromitites Constrained by Ar/Ar Dating of Chrome Chlorites

    Directory of Open Access Journals (Sweden)

    Wei Guo

    2018-05-01

    Full Text Available Chrome chlorites are usually found as secondary phases formed by hydrothermal alteration of chromite deposits and associated mafic/ultramafic rocks. Here, we report the 40Ar/39Ar age of chrome chlorites separated from the Luobusa massive chromitites which have undergone secondary alteration by CO2-rich hydrothermal fluids. The dating results reveal that the intermediate heating steps (from 4 to 10 of sample L7 generate an age plateau of 29.88 ± 0.42 Ma (MSWD = 0.12, plateau 39Ar = 74.6%, and the plateau data points define a concordant inverse isochron age of 30.15 ± 1.05 Ma (MSWD = 0.08, initial 40Ar/36Ar = 295.8 ± 9.7. The Ar release pattern shows no evidence of later degassing or inherited radiogenic component indicated by an atmospheric intercept, thus representing the age of the hydrothermal activity. Based on the agreement of this hydrothermal age with the ~30 Ma adakitic plutons exposed in nearby regions (the Zedong area, tens of kilometers west Luobusa and the extensive late Oligocene plutonism distributed along the southeastern Gangdese magmatic belt, it is suggested that the hydrothermal fluids are likely related to the ~30 Ma magmatism. The hydrothermal fluid circulation could be launched either by remote plutons (such as the Sangri granodiorite, the nearest ~30 Ma pluton west Luobusa or by a similar coeval pluton in the local Luobusa area (inferred, not found or reported so far. Our results provide important clues for when the listwanites in Luobusa were formed.

  20. http://www.bioline.org.br/js 104 Penetrating Tracheal Injuries – A ...

    African Journals Online (AJOL)

    jen

    airway and prompt repair is the mainstay of management of penetrating tracheal injuries. Introduction ... tracheal injury was made in the 16th century ... Pearson 7 Harrington8 Sheely9 and Hood10 ..... Ed Am Col Surg (Chicago) .p.391. 12.

  1. http://www.bioline.org.br/js 37 The Prevalence Overexpression Of C ...

    African Journals Online (AJOL)

    jen

    The Prevalence Overexpression Of C-Erbb-2 Oncoprotein In Carcinoma Of The Prostate-. Mulago Hospital. R. Alenyo1, M. Odida2, S Watya1. 1Department of Surgery, 2Department of Pathology, Makerere University, Kampala – Uganda. Correpondence to: Dr. Rose Alenyo, Email: Rose Alenyo ,.

  2. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    Cervical myelopathy from traditional bonesetters' treatment of spinal injury. O.E. Idowu1,2, O.C. ... patient management by this sect of health providers are still a burden in our society. ... rotation of the cervical spine takes place at this joint2.

  3. http://www.omjournal.org/fultext_PDF.aspx?DetailsID=544&type=fultext

    Directory of Open Access Journals (Sweden)

    Ahmed Al-Mandhari

    2014-07-01

    Full Text Available Objective: To illustrate the patient safety culture in Oman as gleaned via 12 indices of patient safety culture derived from the Hospital Survey on Patient Safety Culture (HSPSC and to compare the average positive response rates in patient safety culture between Oman and the USA, Taiwan, and Lebanon. Methods: This was a cross-sectional research study employed to gauge the performance of HSPSC safety indices among health workers representing five secondary and tertiary care hospitals in the northern region of Oman. The participants (n=398 represented different professional designations of hospital staff. Analyses were performed using univariate statistics. Results: The overall average positive response rate for the 12 patient safety culture dimensions of the HSPSC survey in Oman was 58%. The indices from HSPSC that were endorsed the highest included ‘organizational learning and continuous improvement’ while conversely, ‘non-punitive response to errors’ was ranked the least. There were no significant differences in average positive response rates between Oman and the United States (58% vs. 61%; p=0.666, Taiwan (58% vs. 64%; p=0.386, and Lebanon (58% vs. 61%; p=0.666. Conclusion: This study provides the first empirical study on patient safety culture in Oman which is similar to those rates reported elsewhere. It highlights the specific strengths and weaknesses which may stem from the specific milieu prevailing in Oman.

  4. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    Technology, Mbarara, Uganda .Correspondence to: ... of emergency department visits.4 Abdominal trauma is a leading cause of morbidity and mortality ... patient's medical records (i.e. referral form, if he had been referred) was done. For the ...

  5. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    HIV and Male Fertility at the University Teaching Hospital Lusaka ... diagnosis of infertility seen at the Urology Clinic, to the national HIV prevalence among men of ... Infertile. Population. Figure 1. Frequency of HIV in Infertile and Normal Population. Discussion. HIV infection affects male and female reproduction. Females ...

  6. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    Choking sensation41 can be reduced by an antitussive e.g. oral morphine ... This is due to the local effects of dysphagia and odynophagia in addition to the ... of not only pain and other physical symptoms but also psychological, social and ...

  7. http://www.omjournal.org/fultext_PDF.aspx?DetailsID=450&type=fultext

    Directory of Open Access Journals (Sweden)

    Ritu Lakhtakia

    2013-11-01

    Full Text Available Solid pseudopapillary neoplasm of the pancreas is a rare tumor of the pancreas often detected initially on imaging. Of uncertain histogenesis, it has a low-grade malignant potential with excellent post-surgical curative rates and rare metastasis. Despite advances in imaging, pseudocysts and other cystic neoplasms feature in the differential diagnosis. Pathological and/or cytological evaluation remains the gold standard in reaching a definitive diagnosis. On morphology alone, other primary pancreatic tumors and metastatic tumors pose a diagnostic challenge. Recent advances in immunohistochemical characterization have made the histopathologic diagnosis more specific and, in turn, shed light on the likely histogenesis of this rare tumor. We report a case of solid pseudopapillary neoplasm of the pancreas that was suspected on radiology and diagnosed intraoperatively on imprint cytology guiding definitive surgery. The diagnostic dilemmas are reviewed.

  8. All rights reserved and www.bioline.org.br/ja Assessment of Tree ...

    African Journals Online (AJOL)

    PROF HORSFALL

    recent times, thereby posing appreciable risk of local extinction to some ... Fig 1: Map showing study area; fresh and mangrove swamp of. University of Lagos .... African oil palm. 43. 10. 29. ... Brazilian rose tree, blue trumpet tree. 52. 13. 41.

  9. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    retrospective analysis of 95 patients and review of literature. Otolaryngol Pol. 1996;. 50(6): 567-78. 7. Lee JH, Smith RJ. Recurrent respiratory papillomatosis: pathogenesis to treatment. Curr. Opin Otolaryngol Head Neck Surg. 2005 Dec; 13(6): 354-9. 8. Rosen CA, Woodsen GE, Thompson JW, Hengesteg AP, Bradlow HL.

  10. http://www.bioline.org.br/js 101 Aetiological Profile of Facial Nerve ...

    African Journals Online (AJOL)

    jen

    Background: Facial nerve abnormalities represent a broad spectrum of lesions which are commonly seen by the otolaryngologist. The aim of this paper is to highlight the aetiologic profile of facial nerve palsy. Methods: A retrospective study of patients with facial nerve palsy seen in the Ear, Nose and Throat clinic for 5 years.

  11. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    East and Central African Journal of Surgery ... Investigations and intra-operative findings were suggestive of testicular torsion. We report this case because of its unusual ... The diagnosis is made mainly through clinical examination and signs.

  12. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    The youth and young adults were the ... The time interval between the trauma and the patient arrival at the hospital and management ... findings and outcome of management of traumatic haemoperitoneum. Patients .... Sport (Football). 3. 1. 4.0.

  13. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    This increases the chances of misdiagnosis with resultant complications and sometimes need-less surgery. The causes of scrotal pain include epididymitis, epididymo- orchitis, testicular torsion, appendicular torsion, trauma, Fournier's gangrene, testicular vasculitis, testicular tumor with tumor necrosis or haemorrhage into it ...

  14. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    populations in Asia, far-east, and North America. By far reported cases ... Zomba Central hospital with long standing history of a giant scalp cutenous horn for about 28 years .Excision ... educative pathologies goes under reported. Case Report.

  15. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    and there were no signs of brain atrophy on the CT scan. In addition, many authors believe that pregnancy increases the risk of stroke16. The bridging veins may rupture after a sudden increased pressure during labour and delivery15, due to venous congestion during pregnancy. A pre- existing aneurysm may also rupture ...

  16. East and Central African Journal of Surgery http://www.bioline.org.br ...

    African Journals Online (AJOL)

    Patrick

    3Department of surgery, Faculty of Medicine, Addis Ababa University (AAU), Addis ... In animal study, VAD decreased thyroidal iodine uptake and impaired thyroglobulin (Tg) ..... group A and 12/95 in group B; small were vitamin A deficient.

  17. An 40 Ar- 39 Ar study of the Cape Verde hot spot

    DEFF Research Database (Denmark)

    Holm, Paul Martin; Grandvuinet, Tanja; Wilson, James Richard

    2008-01-01

    The 40Ar-39Ar analyses of 28 groundmass separates from volcanic rocks from the islands of Santiago, Sal, and São Vicente, Cape Verde archipelago, are presented. The new age data record the volcanic evolution for Santiago from 4.6 to 0.7 Ma, for Sal from around 15 to 1.1 Ma, and for São Vicente from...... Cretaceous age for limestones deposited on the seafloor and later uplifted. The Cape Verde Rise is indicated to have fully formed in the early Miocene around 22 Ma, accompanied by the initial alkaline volcanism. Considerable volcanism on Sal, Boa Vista, and Maio took place in the Miocene and Pliocene...

  18. WWW-based remote analysis framework for UniSampo and Shaman analysis software

    International Nuclear Information System (INIS)

    Aarnio, P.A.; Ala-Heikkilae, J.J.; Routti, J.T.; Nikkinen, M.T.

    2005-01-01

    UniSampo and Shaman are well-established analytical tools for gamma-ray spectrum analysis and the subsequent radionuclide identification. These tools are normally run locally on a Unix or Linux workstation in interactive mode. However, it is also possible to run them in batch/non-interactive mode by starting them with the correct parameters. This is how they are used in the standard analysis pipeline operation. This functionality also makes it possible to use them for remote operation over the network. Framework for running UniSampo and Shaman analysis using the standard WWW-protocol has been developed. A WWW-server receives requests from the client WWW-browser and runs the analysis software via a set of CGI-scripts. Authentication, input data transfer, and output and display of the final analysis results is all carried out using standard WWW-mechanisms. This WWW-framework can be utilized, for example, by organizations that have radioactivity surveillance stations in a wide area. A computer with a standard internet/intranet connection suffices for on-site analyses. (author)

  19. Supplemental figure: Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at $\\mathbf{\\sqrt{{\\textit s}_{\\rm NN}}}$ = 2.76 TeV

    CERN Document Server

    2015-01-01

    This note provides a supplemental figure for data on ``Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions $\\mathbf{\\sqrt{{\\textit s}_{\\rm NN}}}$ = 2.76~TeV" published in \\href{http://www.sciencedirect.com/science/article/pii/S037026931300004X}{Phys.\\ Lett.\\ B {\\bf 719}, 18 (2013)}, \\href{http://arxiv.org/abs/1205.5761}{arXiv:1205.5761}. The figure~(\\ref{fig:v2_pid}) presents the $v_2$ of charged pions and protons (particles and anti-particles are not distinguished in this analysis) from the event plane method as a function of transverse momentum for different centrality classes as reported in Fig. 5 of the \\href{http://www.sciencedirect.com/science/article/pii/S037026931300004X}{publication}. The proton $v_2$ is higher than that of pions out to $\\pt=8$~GeV/$c$ where the uncertainties become large.

  20. Origem e distribuição do nervo toracodorsal em fetos de suínos da linhagem Pen Ar Lan

    OpenAIRE

    Mendonça Tavares, Eleusa Marta; França Ortega, Juliana; de Oliveira Honorato, Angelita das Graças; dos Santos, Lázaro Antônio; Ozanam Carneiro e Silva, Frederico

    2011-01-01

    http://dx.doi.org/10.5007/2175-7925.2012v25n1p111 Considerando a importância dos nervos que compõem o plexo braquial, objetivou-se estudar a origem e distribuição do nervo toracodorsal. Dessa forma, foram utilizados 30 fetos de suínos da linhagem Pen Ar Lan obtidos de abortos naturais em criatórios da região do Triângulo Mineiro. As peças foram preparadas por meio de injeções de soluções de Neoprene Látex “450” a 50% e de formaldeído a 10%, na artéria aorta descendente, e imersão nessa me...

  1. Electronic-state distribution of Ar* produced from Ar+(2P3/2)/2e- collisional radiative recombination in an argon flowing afterglow

    International Nuclear Information System (INIS)

    Tsuji, Masaharu; Matsuzaki, Toshinori; Tsuji, Takeshi

    2002-01-01

    The Ar + /2e - collisional radiative recombination has been studied by observing UV and visible emissions of Ar* in an Ar flowing afterglow. In order to clarify recombination mechanism, the Ar + ( 2 P 3/2 ) spin-orbit component was selected by using a filter gas of the Ar + ( 2 P 1/2 ) component. Spectral analysis indicated that 34 Ar*(4p, 4d, 5p, 5d, 6s, 6p, 6d, 4p ' , 4d ' , 5p ' , 5d ' , 6s ' ) states in the 13.08-15.33 eV range are produced. The electronic-state distribution decreased with an increase in the excitation energy of Ar*, which was expressed by a Boltzmann electronic temperature of 0.54 eV. The formation ratios of the 4p: 4d + 5p + 5d + 6s + 6p + 6d: 4p ' : 4d ' + 5p ' + 5d ' + 6s ' states were 43%, 2.8%, 54%, and 0.31%, respectively. The high formation ratio of the 4p ' state having an Ar + ( 2 P 1/2 ) ion core in the Ar + ( 2 P 3/2 )/2e - recombination indicated that such a two-electron process as an electron transfer to an inner 3p orbital followed by excitation of a 3p electron to an outer 4p orbital occurs significantly. The higher formation ratios of 4d + 5p + 5d + 6s + 6p + 6d than those of 4d ' + 5p ' + 5d ' + 6s ' led us to conclude the formation of these upper states dominantly proceeds through one electron transfer to an outer nl orbital of Ar + ( 2 P 3/2 )

  2. Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening.

    Science.gov (United States)

    Hsu, Cheng-Lung; Liu, Jai-Shin; Lin, Ting-Wei; Chang, Ying-Hsu; Kuo, Yung-Chia; Lin, An-Chi; Ting, Huei-Ju; Pang, See-Tong; Lee, Li-Yu; Ma, Wen-Lung; Lin, Chun-Cheng; Wu, Wen-Guey

    2017-09-19

    Using bicalutamide-androgen receptor (AR) DNA binding domain-ligand binding domain as bait, we observed enrichment of FxxFY motif-containing peptides. Protein database searches revealed the presence of receptor-interacting protein kinase 1 (RIPK1) harboring one FxxFY motif. RIPK1 interacted directly with AR and suppressed AR transactivation in a dose-dependent manner. Domain mapping experiments showed that the FxxFY motif in RIPK1 is critical for interactions with AR and the death domain of RIPK1 plays a crucial role in its inhibitory effect on transactivation. In terms of tissue expression, RIPK1 levels were markedly higher in benign prostate hyperplasia and non-cancerous tissue regions relative to the tumor area. With the aid of computer modeling for screening of chemicals targeting activation function 2 (AF-2) of AR, we identified oxadiazole derivatives as good candidates and subsequently generated a small library of these compounds. A number of candidates could effectively suppress AR transactivation and AR-related functions in vitro and in vivo with tolerable toxicity via inhibiting AR-peptide, AR-coregulator and AR N-C interactions. Combination of these chemicals with antiandrogen had an additive suppressive effect on AR transcriptional activity. Our collective findings may pave the way in creating new strategies for the development and design of anti-AR drugs.

  3. WWW-based environments for collaborative group work

    NARCIS (Netherlands)

    Collis, Betty

    1998-01-01

    Since 1994, we have been involved in the design and use of a series of WWW-based environments to support collaborative group work for students in a technical university in The Netherlands. These environments, and the course re-design that accompanies each new environment, began in April 1994 and

  4. The development of AR book for computer learning

    Science.gov (United States)

    Phadung, Muneeroh; Wani, Najela; Tongmnee, Nur-aiynee

    2017-08-01

    Educators need to provide the alternative educational tools to foster learning outcomes of students. By using AR technology to create exciting edutainment experiences, this paper presents how augmented reality (AR) can be applied in the education. This study aims to develop the AR book for tenth grade students (age 15-16) and evaluate its quality. The AR book was developed based on ADDIE framework processes to provide computer learning on software computer knowledge. The content was accorded with the current Thai education curriculum. The AR book had 10 pages in three topics (the first was "Introduction," the second was "System Software" and the third was "Application Software"). Each page contained markers that placed virtual objects (2D animation and video clip). The obtained data were analyzed in terms of average and standard deviation. The validity of multimedia design of the AR book was assessed by three experts in multimedia design. A five-point Likert scale was used and the values were X¯ =4 .84 , S.D. = 1.27 which referred to very high. Moreover, three content experts, who specialize in computer teaching, evaluated the AR book's validity. The values determined by the experts were X¯ =4 .69 , S.D. = 0.29 which referred to very high. Implications for future study and education are discussed.

  5. Glycogen synthase kinase-3 inhibitors suppress the AR-V7-mediated transcription and selectively inhibit cell growth in AR-V7-positive prostate cancer cells.

    Science.gov (United States)

    Nakata, Daisuke; Koyama, Ryokichi; Nakayama, Kazuhide; Kitazawa, Satoshi; Watanabe, Tatsuya; Hara, Takahito

    2017-06-01

    Recent evidence suggests that androgen receptor (AR) splice variants, including AR-V7, play a pivotal role in resistance to androgen blockade in prostate cancer treatment. The development of new therapeutic agents that can suppress the transcriptional activities of AR splice variants has been anticipated as the next generation treatment of castration-resistant prostate cancer. High-throughput screening of AR-V7 signaling inhibitors was performed using an AR-V7 reporter system. The effects of a glycogen synthase kinase-3 (GSK3) inhibitor, LY-2090314, on endogenous AR-V7 signaling were evaluated in an AR-V7-positive cell line, JDCaP-hr, by quantitative reverse transcription polymerase chain reaction. The relationship between AR-V7 signaling and β-catenin signaling was assessed using RNA interference. The effect of LY-2090314 on cell growth in various prostate cancer cell lines was also evaluated. We identified GSK3 inhibitors as transcriptional suppressors of AR-V7 using a high-throughput screen with an AR-V7 reporter system. LY-2090314 suppressed the reporter activity and endogenous AR-V7 activity in JDCaP-hr cells. Because silencing of β-catenin partly rescued the suppression, it was evident that the suppression was mediated, at least partially, via the activation of β-catenin signaling. AR-V7 signaling and β-catenin signaling reciprocally regulate each other in JDCaP-hr cells, and therefore, GSK3 inhibition can repress AR-V7 transcriptional activity by accumulating intracellular β-catenin. Notably, LY-2090314 selectively inhibited the growth of AR-V7-positive prostate cancer cells in vitro. Our findings demonstrate the potential of GSK3 inhibitors in treating advanced prostate cancer driven by AR splice variants. In vivo evaluation of AR splice variant-positive prostate cancer models will help illustrate the overall significance of GSK3 inhibitors in treating prostate cancer. © 2017 Wiley Periodicals, Inc.

  6. ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer.

    Science.gov (United States)

    Lev, Avital; Lulla, Amriti R; Ross, Brian C; Ralff, Marie D; Makhov, Petr B; Dicker, David T; El-Deiry, Wafik S

    2018-05-01

    Androgen receptor (AR) signaling plays a key role in prostate cancer progression, and androgen deprivation therapy (ADT) is a mainstay clinical treatment regimen for patients with advanced disease. Unfortunately, most prostate cancers eventually become androgen-independent and resistant to ADT with patients progressing to metastatic castration-resistant prostate cancer (mCRPC). Constitutively activated AR variants (AR-V) have emerged as mediators of resistance to AR-targeted therapy and the progression of mCRPC, and they represent an important therapeutic target. Out of at least 15 AR-Vs described thus far, AR-V7 is the most abundant, and its expression correlates with ADT resistance. ONC201/TIC10 is the founding member of the imipridone class of small molecules and has shown anticancer activity in a broad range of tumor types. ONC201 is currently being tested in phase I/II clinical trials for advanced solid tumors, including mCRPC, and hematologic malignancies. There has been promising activity observed in patients in early clinical testing. This study demonstrates preclinical single-agent efficacy of ONC201 using in vitro and in vivo models of prostate cancer. ONC201 has potent antiproliferative and proapoptotic effects in both castration-resistant and -sensitive prostate cancer cells. Furthermore, the data demonstrate that ONC201 downregulates the expression of key drivers of prostate cancer such as AR-V7 and downstream target genes including the clinically used biomarker PSA (KLK3). Finally, the data also provide a preclinical rationale for combination of ONC201 with approved therapeutics for prostate cancer such as enzalutamide, everolimus (mTOR inhibitor), or docetaxel. Implications: The preclinical efficacy of ONC201 as a single agent or in combination, in hormone-sensitive or castration-resistant prostate cancer, suggests the potential for immediate clinical translation. Mol Cancer Res; 16(5); 754-66. ©2018 AACR . ©2018 American Association for Cancer

  7. AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

    Directory of Open Access Journals (Sweden)

    Michael T. Schweizer

    2017-01-01

    Full Text Available In the 1940s Charles Huggins reported remarkable palliative benefits following surgical castration in men with advanced prostate cancer, and since then the androgen receptor (AR has remained the main therapeutic target in this disease. Over the past couple of decades, our understanding of AR-signaling biology has dramatically improved, and it has become apparent that the AR can modulate a number of other well-described oncogenic signaling pathways. Not surprisingly, mounting preclinical and epidemiologic data now supports a role for AR-signaling in promoting the growth and progression of several cancers other than prostate, and early phase clinical trials have documented preliminary signs of efficacy when AR-signaling inhibitors are used in several of these malignancies. In this article, we provide an overview of the evidence supporting the use of AR-directed therapies in prostate as well as other cancers, with an emphasis on the rationale for targeting AR-signaling across tumor types.

  8. AR Signaling in Human Malignancies: Prostate Cancer and Beyond.

    Science.gov (United States)

    Antonarakis, Emmanuel S

    2018-01-18

    The notion that androgens and androgen receptor (AR) signaling are the hallmarks of prostate cancer oncogenesis and disease progression is generally well accepted. What is more poorly understood is the role of AR signaling in other human malignancies. This special issue of Cancers initially reviews the role of AR in advanced prostate cancer, and then explores the potential importance of AR signaling in other epithelial malignancies. The first few articles focus on the use of novel AR-targeting therapies in castration-resistant prostate cancer and the mechanisms of resistance to novel antiandrogens, and they also outline the interaction between AR and other cellular pathways, including PI3 kinase signaling, transcriptional regulation, angiogenesis, stromal factors, Wnt signaling, and epigenetic regulation in prostate cancer. The next several articles review the possible role of androgens and AR signaling in breast cancer, bladder cancer, salivary gland cancer, and hepatocellular carcinoma, as well as the potential treatment implications of using antiandrogen therapies in these non-prostatic malignancies.

  9. [SciELO Public Health: the performance of Cadernos de Saúde Pública and Revista de Saúde Pública].

    Science.gov (United States)

    Barata, Rita Barradas

    2007-12-01

    The aim of this paper was to analyze two Brazilian scientific journals included in the SciELO Library of Public Health, using a group of bibliometric indicators and scrutinizing the articles most viewed. Cadernos de Saúde Pública was accessed 3,743.59 times per month, with an average of 30.31 citations per article. The 50 articles most viewed (6.72 to 524.5 views) were mostly published in Portuguese (92%). 42% were theoretical essays, 20% surveys, and 16% descriptive studies. 42% used argumentative techniques, 34% quantitative techniques, 18% qualitative techniques, and 6% mathematical modeling. The most common themes were: health and work (50%), epidemiology (22%), and environmental health (8%). Revista de Saúde Pública was accessed 1,590.97 times per month, with an average of 26.27 citations per article. The 50 articles most viewed (7.33 and 56.50 views) were all published in Portuguese: 46% were surveys, 14% databases analysis, and 12% systematic reviews. Quantitative techniques were adopted in 66% of such articles, while mathematical modeling was the same as observed in Cadernos de Saúde Pública, as were qualitative techniques. The most common themes were health services organization (22%), nutrition (22%), health and work (18%), epidemiology (12%), and environmental health (12%).

  10. Fusion-fission in Ar-heavy nuclei collisions

    International Nuclear Information System (INIS)

    Zaric, Alexandre

    1984-01-01

    Fusion-fission products have been studied for three reactions: Ar + Au, Ar + Bi and Ar + U (5.25-7.5 MeV/u). By measuring symmetric fragmentation components (fission-like events), cross sections for fusion were deduced and compared with the prediction of static and dynamic models. With increasing projectile energy, the width of the mass distributions strongly increases for the two lighter systems. By contrast, for Ar + U it remains essentially constant at a very large value. These results clearly demonstrate that the large increase of the width of the mass distribution cannot be attributed simply to large values of the angular momentum. However, they can be explained by the occurrence of a different dissipative process, fast fission, which can be expected if there is no barrier to fission. For the reaction Ar + Au, the total kinetic-energy distributions were also studied in detail. In this case fast fission occurs only at high incident energy. The average total kinetic energy (TKE) was found to be constant with increasing energy. (author) [fr

  11. Electron temperatures of inductively coupled Cl2-Ar plasmas

    International Nuclear Information System (INIS)

    Fuller, N.C.M.; Donnelly, Vincent M.; Herman, Irving P.

    2002-01-01

    Trace rare gases optical emission spectroscopy has been used to measure the electron temperature, T e , in a high-density inductively coupled Cl 2 -Ar plasma at 18 mTorr as function of the 13.56 MHz radio frequency power and Ar fraction. Only the Kr and Xe emission lines were used to determine T e , because of evidence of radiation trapping when the Ar emission lines were also used for larger Ar fractions. At 600 W (10.6 W cm-2), T e increases from ∼4.0±0.5 eV to ∼6.0±2.0 eV as the Ar fraction increases from 1% to 96%. In the H (inductive, bright) mode, T e , for a 'neat' chlorine plasma (including 1% of each He/Ne/Ar/Kr/Xe) increases only slightly from ∼3.8 to 4.0 eV as power increases from 450 to 750 W. This increase is much larger for larger Ar fractions, such as from ∼4.0 to 7.3 eV for 78% Ar. Most of these effects can be understood using the fundamental particle balance equation

  12. Improvement of WWW chart of the nuclides interface

    International Nuclear Information System (INIS)

    Okamoto, Tsutomu; Minato, Futoshi; Iwamoto, Osamu; Koura, Hiroyuki

    2016-03-01

    The booklet 'chart of the nuclides' is issued every 4 years since 1976 from Nuclear Data Center, Japan Atomic Energy Agency. The chart of the nuclides for WWW (World Wide Web) was developed in 1999 in order to be available from the Internet browser. The Internet connection speeds, browser functions and JavaScript libraries has, however, progressed at present compared with the Internet technology in those days. In connection with the release of the 2014 edition of the chart of the nuclides, the interface of the WWW chart of the nuclides has been improved by introducing new Internet technologies aiming at enhancing convenience on accessibilities via browsers. We introduced a scrolling screen that would make capabilities of easy screen movement on a map with the addition of the drag scrolling function. Considering smart phone access, the light-weight edition which introduced automatic switch was prepared. The new system results in reduction in access time and usefulness in mobile environment. The method of making figures of the chart was reconsidered due to addition of new decay schemes to the 2014 edition. SVG (Scalable Vector Graphics) was adopted so as to make figures easily. It is concluded that the accessibilities of WWW chart of the nuclides are substantially improved from the previous version by introducing the new technologies. (author)

  13. Ars Electronica

    DEFF Research Database (Denmark)

    Kristensen, Thomas Bjørnsten

    2009-01-01

    Anmeldelse af Ars Electronica festivalen 3. - 8. september, 2009 i Linz, Østrig, der fejrede 30 års jubilæum under temaet "Human Nature". Festivalen fokuserer på interaktion mellem menneske, teknologi, kunst og samfund med særlig vægt på udviklingen af computeren og det digitale. Udgivelsesdato: 15.12...

  14. Heterogeneous 40Ar/39Ar laser probe apparent ages in low-grade mylonitic rocks: Constraining a meaningful geological age

    International Nuclear Information System (INIS)

    Arancibia, G

    2001-01-01

    Obtaining meaningful geological ages from mylonitic rocks has been a major problem for structural geologist, because apparent ages have usually no geologic significance. Over the last years, in situ high spatial resolutions 40 Ar/ 39 Ar studies (e.g. Ruffet et al., 1991; Reddy et al., 1996; Pickles et al., 1997), permit obtain apparent ages of mineral and link them directly with textural, microstructural and chemical patterns that can previously be obtained by optical and scanning electron (SEM) microscopes and electron microprobe. In this work, heterogeneous 40 Ar/ 39 Ar laser probe ages from low-grade volcanic mylonites show complex argon distributions patterns. Inverse isochron analysis suggests that most obtained apparent ages contain argon excess and only younger ages have a meaningful geologically interpretation (au)

  15. 10.5402 | dx.doi.org

    Indian Academy of Sciences (India)

    Home; public; Volumes; pram; 082; 01; dx.doi.org; 10.5402; 2012; 631504.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th ...

  16. A composite microdose Adaptive Response (AR) and Bystander Effect (BE) model-application to low LET and high LET AR and BE data.

    Science.gov (United States)

    Leonard, Bobby E

    2008-08-01

    It has been suggested that Adaptive Response (AR) may reduce risk of adverse health effects due to ionizing radiation. But very low dose Bystander Effects (BE) may impose dominant deleterious human risks. These conflicting behaviors have stimulated controversy regarding the Linear No-Threshold human risk model. A dose and dose rate-dependent microdose model, to examine AR behavior, was developed in prior work. In the prior work a number of in vitro and in vivo dose response data were examined with the model. Recent new data show AR behavior with some evidence of very low dose BE. The purpose of this work is to supplement the microdose model to encompass the Brenner and colleagues BaD (Bystander and Direct Damage) model and apply this composite model to obtain new knowledge regarding AR and BE and illustrate the use of the model to plan radio-biology experiments. The biophysical composite AR and BE Microdose Model quantifies the accumulation of hits (Poisson distributed, microdose specific energy depositions) to cell nucleus volumes. This new composite AR and BE model provides predictions of dose response at very low dose BE levels, higher dose AR levels and even higher dose Direct (linear-quadratic) Damage radiation levels. We find good fits of the model to both BE data from the Columbia University microbeam facility and combined AR and BE data for low Linear Energy Transfer (LET) and high LET data. A Bystander Factor of about 27,000 and an AR protection factor of 0.61 are obtained for the low LET in vivo mouse spleen exposures. A Bystander Factor of 317 and an AR protection factor of 0.53 are obtained for high LET radon alpha particles in human lymphocytes. In both cases the AR is activated at most by one or two radiation induced charged particle traversals through the cell nucleus. The results of the model analysis is consistent with a premise that both Bystander damage and Adaptive Response radioprotection can occur in the same cell type, derived from the same

  17. 40Ar/39Ar geochronology of the El Teniente porphyry copper deposit

    International Nuclear Information System (INIS)

    Maksaev, V; Munizaga, F; McWilliams, M; Thiele, K; Arevalo, A; Zuniga, P; Floody, R

    2001-01-01

    breccias. Phyllic alteration primarily occurs as quartz-sericite haloes of quartz-sulfide-sulfate veinlets within the perimeter of the orebody, and slightly overprints potassic alteration. Propylitic alteration occurs largely peripheral to ore-grade rock. The relatively restricted development of phyllic alteration and the occurrence of the central breccia conflict with the classic porphyry copper model of Lowell and Gilbert (1970), but El Teniente may be regarded as a 'variation on a theme' of the classic model, as suggested by Gustafson and Hunt (1975). The exceedingly large size of the El Teniente deposit, coupled with its apparently young mineralization age prompted us to initiate a systematic 40 Ar/ 39 Ar study whose goals are to determine the age(s) of the hydrothermal event(s) that produced such a remarkable copper concentration and ultimately to estimate the duration of the hydrothermal activity at El Teniente. This is particularly relevant to an understanding of the processes that formed super-giant high-grade copper deposits in the Chilean Andes and elsewhere. We report here 32 total fusion 40 Ar/ 39 Ar ages from sericite and biotite from different lithologic units of El Teniente and five step-heating 40 Ar- 39 Ar ages of samples previously dated using conventional K-Ar methods (Cuadra, 1986) (au)

  18. 40Ar/39Ar dating and geochemistry of tholeiitic magmatism related to the early opening of the Central Atlantic rift

    International Nuclear Information System (INIS)

    Sebai, A.; Feraud, G.; Bertrand, H.; Hanes, J.

    1991-01-01

    Tholeiitic effusive and intrusive magnetism from Iberia, Morocco, Algeria and Mali, realted to the early opening of the Central Atlantic rift, was dated by the 40 Ar/ 39 Ar step-heating method. Four plateau ags, rangin from 203.7±2.7 to 197.1±1.8 Ma, were obtained on plagioclase from dykes from theTaoudenni area (Mali) and two lava flows from Morocco. The Messejana dyke (Iberia), which previously yielded discrepant conventional K-Ar dates, did not furnish any 40 Ar/ 39 Ar plateau dates. However, there is a clear inverse relationship between apparent age and K/Ca atio for gas fractions from a plagioclase separate (proportional to the alteration degree) which, combined with dates obtained on amphibole, biotite and pyroxene, allows us to determine an age of around 200 Ma for this body. These data, and those obtained on the Foum Zguid (Morocco) and the Ksi Ksou (Algeria) dykes, give evidence of a brief magmatic event (between 206 and 195 Ma ago) which affected a large area ca. 2500 km long. Trace-element modelling shows that most of these formations originated from a homogeneous, enriched, source material. Such a brief magmatic episode related to the opening of a continental rift is in agreement with findings in other magmatic provinces (e.g. the Deccan traps and the Red Sea rift, precisely dated by the 40 Ar/ 39 Ar method as well). (orig.)

  19. Exposición ocupacional y ambiental al arsénico: actualización bibliográfica para investigación científica

    Directory of Open Access Journals (Sweden)

    Augusto V. Ramírez

    2013-07-01

    Full Text Available El arsénico (As es un metaloide presente en minerales complejos que contienen cobre, plomo y otros; en el trabajador causa arsenicismo ocupacional y la principal exposición ocurre en metalurgia del cobre. Sus compuestos trivalentes tienen tendencia acumulativa e ingresan por las vías respiratoria, digestiva o cutánea y se transforman en los ácidos dimetilarsínico y metilarsónico. En la mitocondria, con el azufre de los grupos mercapto forma enlaces covalentes y desacopla la fosforilación oxidativa, sugiriendo una acción inhibitoria no hidrolítica a ese nivel. Es cancerígeno para varios órganos. Se excreta por orina, heces y piel. Los peces y mariscos contienen arsénico orgánico. En sujetos no expuestos, dependiendo de la dieta, el As inorgánico en orina es < 5 ug/L. El índice de exposición biológica para trabajadores medido al final de la semana laboral es 35 µg/g creatinina y el valor límite umbral para ambientes de trabajo es 0,01mg/m³. La arsina es el compuesto arsenical más tóxico. El arsénico contenido en el agua de ciertas regiones produce la enfermedad ambiental llamada hidroarsenicismo crónico regional endémico.

  20. Strategy of development and online marketing for website www.skutecnydarek.cz

    OpenAIRE

    Fodor, Aleš

    2011-01-01

    The goal of this bachelor's thesis is to suggest particular online marketing strategy for People in need's website - www.skutecnydarek.cz. Firstly the thesis is going to aim at analysing the present condition of marketing activities and the quality of the web site for www.skutecnydarek.cz. Then the online marketing strategy is going be developed.

  1. CSIR and its activities in the European Union's (EU) framework programmes (FPs): special focus on FP6

    CSIR Research Space (South Africa)

    Meese, G

    2006-02-01

    Full Text Available for human health 1 Fraunhofer Institute, Germany www.pharma-planta.org FLOSSWorld Free/Libre/Open Source Software: Worldwide impact study 2 University of Maastricht - UNU-MERIT, The Netherlands http://www.flossworld.org/ index.php IST...-Africa Regional Impact of Information Society Technologies in Africa 2 International Information Management Corporation Limited, Ireland http://www.ist-africa. org/2005/ EUDEVLAS A framework for innovation comprising EU and Developing...

  2. ARABIC LIGHT STEMMER (ARS

    Directory of Open Access Journals (Sweden)

    ASMA AL-OMARI

    2014-12-01

    Full Text Available Stemming is a main step used to process textual data. It is usually used in several types of applications such as: text mining, information retrieval (IR, and natural language processing (NLP. A major task in stemming is to standardize words; which can be achieved by reducing each word to its base (root or stem. Arabic stemming is not an easy task. Unlike other languages, Arabic language is a highly inflected language, since it uses many inflectional forms. Researchers are divided on the benefit of using stemming in fields of IR, NLP...etc., since in Arabic the morphological variants of a certain word are not always semantically related. The aim of this paper is to design and implement a new Arabic light stemmer (ARS which is not based on Arabic root patterns. Instead, it depends on well defined mathematical rules and several relations between letters. A series of tests were conducted on ARS stemmer to compare its effectiveness with the effectiveness of two other Arabic stemmers. Test shows clearly the effectiveness superiority of ARS compared to effectiveness of these two Arabic stemmers.

  3. Norwegian long-term care: Legacies, trends, and controversies - See more at: http://www.gigapp.org/index.php/component/jresearch/?view=publication&task=show&id=1807#sthash.eCzEqbqK.dpuf

    Directory of Open Access Journals (Sweden)

    Daatland, SveinOlav

    2015-02-01

    ? Have the policy tools (services, transfers, funding or models of provision changed? To what extent have these policies been successful in coping with social and economic problems? To what extent a social demand in favour of these changes exist? What are the main political and social actors intervening as stakeholders in these policies? Finally, what are the major similarities and differences existing between the two countries? To what extent are there policy proposals that might easily travel between them? Could they foster mutually enriching exchanges of information? - See more at: http://www.gigapp.org/index.php/component/jresearch/?view=publication&task=show&id=1807#sthash.GBgfdaqa.dpuf

  4. 40Ar/39Ar Dating of Zn-Pb-Ag Mineralization in the Northern Brooks Range, Alaska

    Science.gov (United States)

    Werdon, Melanie B.; Layer, Paul W.; Newberry, Rainer J.

    2004-01-01

    The 40Ar/39Ar laser step-heating method potentially can be used to provide absolute ages for a number of formerly undatable, low-temperature ore deposits. This study demonstrates the use of this method by determining absolute ages for Zn-Pb-Ag sediment-hosted massive sulfide deposits and vein-breccia occurrences found throughout a 300-km-long, east-west-trending belt in the northern Brooks Range, Alaska. Massive sulfide deposits are hosted by Mississippian to Pennsylvanian(?) black carbonaceous shale, siliceous mudstone, and lesser chert and carbonate turbidites of the Kuna Formation (e.g., Red Dog, Anarraaq, Lik (Su), and Drenchwater). The vein-breccia occurrences (e.g., Husky, Story Creek, West Kivliktort Mountain, Vidlee, and Kady) are hosted by a deformed but only weakly metamorphosed package of Upper Devonian to Lower Mississippian mixed continental and marine clastic rocks (the Endicott Group) that stratigraphically underlie the Kuna Formation. The vein-breccias are mineralogically similar to, but not spatially associated with, known massive sulfide deposits. The region's largest shale-hosted massive sulfide deposit is Red Dog; it has reserves of 148 Mt grading 16.6 percent zinc, 4.5 percent lead, and 77 g of silver per tonne. Hydrothermally produced white mica in a whole-rock sample from a sulfide-bearing igneous sill within the Red Dog deposit yielded a plateau age of 314.5 Ma. The plateau age of this whole-rock sample records the time at which temperatures cooled below the argon closure temperature of the white mica and is interpreted to represent the minimum age limit for massive sulfide-related hydrothermal activity in the Red Dog deposit. Sulfide-bearing quartz veins at Drenchwater crosscut a hypabyssal intrusion with a maximum biotite age of 337.0 Ma. Despite relatively low sulfide deposition temperatures in the vein-breccia occurrences (162°-251°C), detrital white mica in sandstone immediately adjacent to large vein-breccia zones was partially to

  5. K-Ar and Ar-Ar dating of the Palaeozoic metamorphic complex from the Mid-Bosnian Schist Mts., Central Dinarides, Bosnia and Hercegovina

    International Nuclear Information System (INIS)

    Pamic, J.; Balogh, K.; Hrvatovic, H.; Balen, D.; Palinkas, L.; Jurkovic, I.

    2004-01-01

    K-Ar and Ar-Ar whole rock and mineral ages are presented for 25 samples of metamorphic rocks from the Mid-Bosnian Schist Mts., representing one of the largest allochthonous Palaeozoic terranes incorporated within the Internal Dinarides. Four main age groups can be distinguished: 1) Variscan (∼ 343 Ma), 2) post-Variscan (288-238 Ma), 3) Early Cretaceous (mainly 121-92 Ma), and 4) Eocene (59--35 Ma) ages. Apart from this, an Oligocene (31 Ma) age was obtained on Alpine vein hyalophane. The radiometric dating indicates a polyphase metamorphic evolution of the Palaeozoic formations and suggests a pre-Carboniferous age of the volcano-sedimentary protoliths, an Early Carboniferous age of Variscan metamorphism and deformation, post-Variscan volcanism, an Early Cretaceous metamorphic overprint related to out-of-sequence thrusting of the Palaeozoic complex, and an Eocene and Oligocene metamorphic overprint related to the main Alpine compressional deformation and subsequent strike-slip faulting, and uplift of the metamorphic core. Accordingly, the Mid-Bosnian Schist Mts. can be correlated in its multistage geodynamic evolution with some Palaeozoic tectonostratigraphic units from the Austroalpine domain in the Eastern Alps. (author)

  6. I-Xe and 40Ar-39Ar dating of silicate from Weekeroo Station and Netschaevo IIE iron meteorites

    International Nuclear Information System (INIS)

    Niemeyer, S.

    1980-01-01

    Silicate inclusions from two IIE iron meteorites were dated by the I-Xe and 40 Ar- 39 Ar techniques. Weekeroo Station, a 'normal' IIE iron, shows no loss of radiogenic 40 Ar at low temperature, and the well defined 40 Ar- 39 Ar plateau yields an age of 4.54 +- 0.03 Byr. The xenon data define a good I-Xe correlation with an age of + 10.9 +- 0.5 Myr relative to Bjurbole. Despite its relatively young age, Weekeroo Station's ( 129 Xe/ 132 Xe)sub(trapped) ratio (= 0.84 +- 0.05) lies significantly below the solar value. Netschaevo silicate has a chondritic composition, unlike 'normal' IIE silicate which is more differentiated. Nevertheless Netschaevo gives a 40 Ar- 39 Ar plateau-age of only 3.79 +- 0.03 Byr, with the xenon data failing to define an I-Xe isochron. Only irons from the IAB and IIE groups contain silicate inclusions, but these two groups differ in many other respects, mostly suggesting that IAB meteorites are more primitive. The I-Xe chronology supports this suggestion inasmuch as Weekeroo Station formed well after IAB silicates. The four silicate-bearing IIE irons which have now been dated can be subdivided into distinct pairs: Weekeroo Station and Colomera formed near the beginning of the solar system, while Netschaevo and Kodaikanal both formed only 3.8 Byr ago. A review of other properties of these meteorites generally supports this subdivision. This work underscores the complexity of the history of IIE meteorites; in particular, an adequate model must account for the formation of two IIE irons at 3.8 Byr without disturbing rare gases in Weekeroo Station. All formation models are quite speculative, but the one which seems best to fit the available evidence postulates two parent bodies: the 3.8 Byr old silicate formed on one parent body, all other IIE material resided in a separate body, and subsequent collision(s) mixed the young silicate with IIE metal. (author)

  7. 40Ar/ 39Ar, K-Ar and 230Th- 238U dating of the Laschamp excursion: A radioisotopic tie-point for ice core and climate chronologies

    Science.gov (United States)

    Singer, Brad S.; Guillou, Hervé; Jicha, Brian R.; Laj, Carlo; Kissel, Catherine; Beard, Brian L.; Johnson, Clark M.

    2009-08-01

    A brief period of enhanced 10Be flux that straddles the interstadial warm period known as Dansgaard-Oeschger event 10 in Greenland and its counterpart in Antarctica, the Antarctic Isotope Maximum 10 is but one consequence of the weakening of Earth's magnetic field associated with the Laschamp excursion. This 10Be peak measured in the GRIP ice core is dated at 41,250 y b2k (= before year 2000 AD) in the most recent GICC05 age model obtained from the NorthGRIP core via multi-parameter counting of annual layers. Uncertainty in the age of the 10Be peak is, however, no better than ± 1630 y at the 95% confidence level, reflecting accumulated error in identifying annual layers. The age of the Laschamp excursion [Guillou, H., Singer, B.S., Laj, C., Kissel, C., Scaillet, S., Jicha, B., 2004. On the age of the Laschamp geomagnetic excursion. Earth Planet. Sci. Lett. 227, 331-343.] is revised on the basis of new 40Ar/ 39Ar, unspiked K-Ar and 238U- 230Th data from three lava flows in the Massif Central, France, together with the 40Ar/ 39Ar age of a transitionally magnetized lava flow at Auckland, New Zealand. Combined, these data yield an age of 40,700 ± 950 y b2k, where the uncertainty includes both analytical and systematic ( 40K and 230Th decay constant) errors. Taking the radioisotopic age as a calibration tie point suggests that the layer-counting chronologies for the NorthGRIP and GISP2 ice cores are more accurate and precise than previously thought at depths corresponding to the Laschamp excursion.

  8. Brancherapport: Z-org benchmarkonderzoek thuiszorg 2004.

    NARCIS (Netherlands)

    2005-01-01

    In 2004-2005 werd voor de derde keer binnen de thuiszorg een benchmarkonderzoek gehouden. Dit qua opzet en scope unieke onderzoek is gehouden onder de leden van Z-org. Het is een vergelijkend onderzoek onder klanten, medewerkers en binnen de zorgorganisaties zelf waarbij het de bedoeling is te leren

  9. Building Trust and Capacity: Disarmament, Demobilization, and Reintegration to Transition Pro-Government Non-State Armed Groups

    Science.gov (United States)

    2009-05-11

    Desenvolupament, Cambodia, http://www.escolapau.org/img/programas/desarme/ mapa /camboyai.pdf (accessed 19 March 2009). In Ethiopia, follow its war with Eritrea...de Pau. “Cambodia.” Escola de Cultura de Pau, http://www.escolapau.org/img/programas/desarme/ mapa /camboyai.pdf (accessed March 20, 2009). 69...Escola de Cultura de Pau. “Eritrea.” Escola de Cultura de Pau, http://www.escolapau.org/img/programas/desarme/ mapa /eritreai.pdf (accessed March 20

  10. Measurements of the 40Ar(n, γ)41Ar radiative-capture cross section between 0.4 and 14.8 MeV

    Science.gov (United States)

    Bhike, Megha; Fallin, B.; Tornow, W.

    2014-09-01

    The 40Ar(n, γ)41Ar neutron capture cross section has been measured between 0.4 and 14.8 MeV neutron energy using the activation technique. The data are important for estimating backgrounds in argon-based neutrino and dark-matter detectors and in the neutrino-less double-beta decay search GERDA, which uses liquid argon as cooling and shielding medium. For the first time the 40Ar(n, γ)41Ar cross section has been measured for neutron energies above 1 MeV. Our results are compared to the evaluation ENDF/B-VII.1 and the calculated prediction TENDL-2013. The latter agrees very well with the present results.

  11. Spatial autocorrelation method using AR model; Kukan jiko sokanho eno AR model no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Obuchi, T; Saito, T [Iwate University, Iwate (Japan). Faculty of Engineering

    1996-05-01

    Examination was made about the applicability of the AR model to the spatial autocorrelation (SAC) method, which analyzes the surface wave phase velocity in a microtremor, for the estimation of the underground structure. In this examination, microtremor data recorded in Morioka City, Iwate Prefecture, was used. In the SAC method, a spatial autocorrelation function with the frequency as a variable is determined from microtremor data observed by circular arrays. Then, the Bessel function is adapted to the spatial autocorrelation coefficient with the distance between seismographs as a variable for the determination of the phase velocity. The result of the AR model application in this study and the results of the conventional BPF and FFT method were compared. It was then found that the phase velocities obtained by the BPF and FFT methods were more dispersed than the same obtained by the AR model. The dispersion in the BPF method is attributed to the bandwidth used in the band-pass filter and, in the FFT method, to the impact of the bandwidth on the smoothing of the cross spectrum. 2 refs., 7 figs.

  12. Factores psicosociales relacionados con la rehospitalización de pacientes con psicosis orgánica

    Directory of Open Access Journals (Sweden)

    Cortés-Padilla María Teresa

    2001-01-01

    Full Text Available Objetivo. Conocer los factores psicosociales relacionados con la frecuente rehospitalización de pacientes con psicosis orgánica. Material y métodos. Estudio de tipo observacional descriptivo, de corte transversal. La muestra estuvo formada por 33 pacientes del Hospital Psiquiátrico Guillermo Dávila, con Unidad de Medicina Familiar Número 10 del Instituto Mexicano del Seguro Social de la Ciudad de México, con psicosis orgánica y quienes durante los años de 1993-1994 presentaron más de dos rehospitalizaciones. Instrumentos: Entrevista grabada, o muestra de conversación de cinco minutos, para la emoción expresada (EE, cuestionarios mixtos para la Concepción de Enfermedad y la Relación médico-paciente. La validez y confiabilidad de los datos se establecieron con las pruebas de Kappa y Alpha de Cronbach y se efectuó análisis estadístico descriptivo e inferencial. Resultados. El 60.9% de los familiares presentan alto nivel de EE, es decir, expresan crítica, hostilidad o sobreinvolucramiento emocional; el 64.3% de los sujetos de la muestra conviven más de 35 horas a la semana con familiares que presentan Alta EE. Conclusiones. Altos niveles de EE estuvieron asociados con los frecuentes reingresos a hospitalización. Existe mayor conocimiento de las características de la enfermedad por parte del familiar que del paciente. La relación médico-paciente es satisfactoria pero no forma conciencia de enfermedad ni propicia apego al tratamiento terapeútico. El texto completo en inglés de este artículo está disponible en: http://www.insp.mx/salud/index.html

  13. El Comercio Internacional de Productos Orgánicos: Retos y Desafíos

    Directory of Open Access Journals (Sweden)

    Evangelina Méndez

    2015-11-01

    Full Text Available Durante las actividades del proyecto de investigación Guía para exportar abono orgánico hacia los principales mercados de Estados Unidos, Europa y Sudamérica, el uso de una plataforma virtual permitió conocer e identificar el impacto de la tecnología en la producción y comercialización de productos orgánicos, que a su vez involucró: el interés por parte de productores orgánicos para darse a conocer a través de medios virtuales, el acceso a equipos que permiten controlar a tiempo eventuales plagas, las oportunidades para obtener certificaciones orgánicas, restricciones e ingreso a mercados internacionales a través de medios virtuales. Este proyecto generó una respuesta que nos vincula directamente con productores orgánicos a nivel nacional e internacional, los resultados de análisis de un abono orgánico demostraron que es necesario realizar un estudio de factibilidad del suelo a través del uso de equipos especializados, laboratorios acreditados y capacitaciones constantes para obtener una certificación orgánica, obligando al productor a alinearse a esta nueva tendencia que le permitirá ingresar en mercados internacionales. Esto a su vez está transformando la agricultura convencional en una agricultura de precisión e inteligente, constituyéndose en un reto para productores y exportadores orgánicos.

  14. re3data.org - a global registry of research data repositories

    Science.gov (United States)

    Pampel, Heinz; Vierkant, Paul; Elger, Kirsten; Bertelmann, Roland; Witt, Michael; Schirmbacher, Peter; Rücknagel, Jessika; Kindling, Maxi; Scholze, Frank; Ulrich, Robert

    2016-04-01

    re3data.org - the registry of research data repositories lists over 1,400 research data repositories from all over the world making it the largest and most comprehensive online catalog of research data repositories on the web. The registry is a valuable tool for researchers, funding organizations, publishers and libraries. re3data.org provides detailed information about research data repositories, and its distinctive icons help researchers to easily identify relevant repositories for accessing and depositing data sets [1]. Funding agencies, like the European Commission [2] and research institutions like the University of Bielefeld [3] already recommend the use of re3data.org in their guidelines and policies. Several publishers and journals like Copernicus Publications, PeerJ, and Nature's Scientific Data recommend re3data.org in their editorial policies as a tool for the easy identification of appropriate data repositories to store research data. Project partners in re3data.org are the Library and Information Services department (LIS) of the GFZ German Research Centre for Geosciences, the Computer and Media Service at the Humboldt-Universität zu Berlin, the Purdue University Libraries and the KIT Library at the Karlsruhe Institute of Technology (KIT). After its fusion with the U.S. American DataBib in 2014, re3data.org continues as a service of DataCite from 2016 on. DataCite is the international organization for the registration of Digital Object Identifiers (DOI) for research data and aims to improve their citation. The poster describes the current status and the future plans of re3data.org. [1] Pampel H, et al. (2013) Making Research Data Repositories Visible: The re3data.org Registry. PLoS ONE 8(11): e78080. doi:10.1371/journal.pone.0078080. [2] European Commission (2015): Guidelines on Open Access to Scientific Publications and Research Data in Horizon 2020. Available: http://ec.europa.eu/research/participants/data/ref/h2020/grants_manual/hi/oa_pilot/h2020-hi

  15. Astronomically calibrated 40Ar/39Ar age for the Toba supereruption and global synchronization of late Quaternary records

    Science.gov (United States)

    Storey, Michael; Roberts, Richard G.; Saidin, Mokhtar

    2012-11-01

    The Toba supereruption in Sumatra, ∼74 thousand years (ka) ago, was the largest terrestrial volcanic event of the Quaternary. Ash and sulfate aerosols were deposited in both hemispheres, forming a time-marker horizon that can be used to synchronize late Quaternary records globally. A precise numerical age for this event has proved elusive, with dating uncertainties larger than the millennial-scale climate cycles that characterized this period. We report an astronomically calibrated 40Ar/39Ar age of 73.88 ± 0.32 ka (1σ, full external errors) for sanidine crystals extracted from Toba deposits in the Lenggong Valley, Malaysia, 350 km from the eruption source and 6 km from an archaeological site with stone artifacts buried by ash. If these artifacts were made by Homo sapiens, as has been suggested, then our age indicates that modern humans had reached Southeast Asia by ∼74 ka ago. Our 40Ar/39Ar age is an order-of-magnitude more precise than previous estimates, resolving the timing of the eruption to the middle of the cold interval between Dansgaard-Oeschger events 20 and 19, when a peak in sulfate concentration occurred as registered by Greenland ice cores. This peak is followed by a ∼10 °C drop in the Greenland surface temperature over ∼150 y, revealing the possible climatic impact of the eruption. Our 40Ar/39Ar age also provides a high-precision calibration point for other ice, marine, and terrestrial archives containing Toba sulfates and ash, facilitating their global synchronization at unprecedented resolution for a critical period in Earth and human history beyond the range of 14C dating.

  16. DISTANT EARLY WARNING SYSTEM for Tsunamis - A wide-area and multi-hazard approach

    Science.gov (United States)

    Hammitzsch, Martin; Lendholt, Matthias; Wächter, Joachim

    2010-05-01

    system and to extend the CCUI with hazard specific functionality. The presentation covers the DEWS project, the system architecture and the CCUI in conjunction with details of information logistics. The DEWS Wide Area Centre connecting national centres to allow the international communication and warning exchange is presented also. REFERENCES: [1] DEWS, www.dews-online.org [2] OGC, www.opengeospatial.org [3] SWE, www.opengeospatial.org/projects/groups/sensorweb [4] Eclipse RCP, www.eclipse.org/home/categories/rcp.php [5] uDig, udig.refractions.net [6] WMS, www.opengeospatial.org/standards/wms [7] WFS, www.opengeospatial.org/standards/wfs [8] WPS, www.opengeospatial.org/standards/wps [9] OASIS, www.oasis-open.org [10] CAP, www.oasis-open.org/specs/#capv1.1 [11] EDXL-DE, www.oasis-open.org/specs/#edxlde-v1.0 [12] SOAP, www.w3.org/TR/soap [13] GITEWS (German Indonesian Tsunami Early Warning System) is a project of the German Federal Government to aid the recon¬struction of the tsunami-prone Indian Ocean region, www.gitews.org [14] The Tsunami Service Bus is the GITEWS sensor system integration platform offering standardised services for the detection and monitoring of tsunamis

  17. Computer programs to make a Chart of the nuclides for WWW

    International Nuclear Information System (INIS)

    Nakagawa, Tsuneo; Katakura, Jun-ichi; Horiguchi, Takayoshi

    1999-06-01

    Computer programs to make a chart of the nuclides for World Wide Web (WWW) have been developed. The programs make a data file for WWW chart of the nuclides from a data file containing nuclide information in the format similar to ENSDF, by filling unknown half-lives with calculated ones. Then, the WWW chart of the nuclides in the gif format is created from the data file. The programs to make html files and image map files, to select a chart of selected nuclides, and to show various information of nuclides are included in the system. All the programs are written in C language. This report describes the formats of files, the programs and 1998 issue of Chart of the Nuclides made by means of the present programs. (author)

  18. Errors in Length-weight Parameters at FishBase.org

    OpenAIRE

    Michael Courtney; Simeon Cole-Fletcher; Lucas Marin-Salcedo; Ajaya Rana

    2011-01-01

    Background: FishBase.org is an on-line database of fish related data that has been cited over 1500 times in the fisheries literature. Length-weight relationships in fish traditionally employ the model, W(L) = aL^b^, where L is length and W is weight. Parameters a and b are catalogued by FishBase for a large number of sources and species. FishBase.org detects outliers in a plot of log(a) vs. b to identify dubious length-weight parameters.

  19. Kiva.org: Crowd-Sourced Microfinance & Cooperation in Group Lending

    OpenAIRE

    Hartley, Scott

    2010-01-01

    At the end of 2008 Kiva.org announced the creation of “Lending Teams,” or cohesive open or closed membership groups established and categorized according to scope. These Lending Teams introduce forms of cooperative many-to-one and many-to-many group lending, based on tenuous concepts of identity. Groups vary according to category, size, scope, and activity, and this impacts participatory vitality of crowd-sourced lending. Looking specifically at Kiva.org as a prominent online community for p...

  20. 75 FR 12163 - Class E Airspace; Mountain View, AR

    Science.gov (United States)

    2010-03-15

    ...-1181; Airspace Docket No. 09-ASW-36] Class E Airspace; Mountain View, AR AGENCY: Federal Aviation... Class E airspace at Mountain View, AR. Decommissioning of the Wilcox non-directional beacon (NDB) at... View, AR. Airspace reconfiguration is necessary due to the decommissioning of the Wilcox NDB and the...

  1. Bone blood flow measured by 41Ar clearance formed by 44Ca(n,α)41Ar

    International Nuclear Information System (INIS)

    Rosenthal, M.S.; DeLuca, P.M. Jr.; Pearson, D.W.; Nickles, R.J.

    1983-01-01

    A technique to measure regional inert gas washout in bone, in vivo, by measuring 41 Ar clearance formed by fast-neutron activation of 44 Ca has been developed. Following fast-neutron irradiation of whole rats, the perfusion-limited clearance of 41 Ar was measured for both dead and living rats. The clearance rate for the live rats indicate that the bone perfusion is in the range of 3 to 20 ml/100 Argon distribution volume

  2. Accessing HEP Collaboration documents using WWW and WAIS

    International Nuclear Information System (INIS)

    Nguyen, T.D.; Buckley-Geer, E.; Ritchie, D.J.

    1995-09-01

    WAIS stands for Wide Area Information Server. It is a distributed information retrieval system. A WAIS system has a client-server architecture which consists of clients talking to a server via a TCP/IP network using the ANSI standard Z39-50 VI protocol. A freely available version (FreeWAIS) is supported by the Clearinghouse for Networked Information Discovery and Retrieval, also known as CNIDR. FreeWAIS-sf, which is the software the authors are using at Fermilab, is an extension of FreeWAIS. FreeWAIS-sf supports all the functionalities which FreeWAIS offers as well as additional indexing and searching capabilities for structured fields. World Wide Web (WWW) was originally developed by Tim Berners-Lee at CERN and is now the backbone for serving information on Internet. Here, the authors describe a system for accessing HEP collaboration documents using WWW and WAIS

  3. Accessing HEP Collaboration documents using WWW and WAIS

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, T.D.; Buckley-Geer, E.; Ritchie, D.J.

    1995-09-01

    WAIS stands for Wide Area Information Server. It is a distributed information retrieval system. A WAIS system has a client-server architecture which consists of clients talking to a server via a TCP/IP network using the ANSI standard Z39-50 VI protocol. A freely available version (FreeWAIS) is supported by the Clearinghouse for Networked Information Discovery and Retrieval, also known as CNIDR. FreeWAIS-sf, which is the software the authors are using at Fermilab, is an extension of FreeWAIS. FreeWAIS-sf supports all the functionalities which FreeWAIS offers as well as additional indexing and searching capabilities for structured fields. World Wide Web (WWW) was originally developed by Tim Berners-Lee at CERN and is now the backbone for serving information on Internet. Here, the authors describe a system for accessing HEP collaboration documents using WWW and WAIS.

  4. Identifying Instability Pockets

    Science.gov (United States)

    2014-12-04

    Shalini Signh, Domestic Tourism in Asia: A Diversity and Divergence (London: Earthscan), 183. 30...125 Solomon. 126 Globalpolicy.Org, “Water In Conflict,” (2014), accessed June 30, 2014, http://www.globalpolicy.org/the- dark -side-of-natural-resources...Globalpolicy.Org. “Water In Conflict,” (2014). Accessed June 30, 2014. http://www.globalpolicy.org/the- dark -side-of-natural-resources-st/water-in-conflict.html

  5. A pulsed plasma jet with the various Ar/N2 mixtures

    Science.gov (United States)

    Barkhordari, A.; Ganjovi, A.; Mirzaei, I.; Falahat, A.; Rostami Ravari, M. N.

    2017-12-01

    In this paper, using the Optical Emission Spectroscopy technique, the physical properties of a fabricated pulsed DBD plasma jet are studied. Ar/N2 gaseous mixture is taken as operational gas, and Ar contribution in Ar/N2 mixture is varied from 75 to 95%. Through the optical emission spectra analysis of the pulsed DBD plasma jet, the rotational, vibrational and excitation temperatures and density of electrons in plasma medium of the pulsed plasma jet are obtained. It is seen that, at the wavelength of 750.38 nm, the radiation intensity from the Ar 4p → 4 s transition increases at the higher Ar contributions in Ar/N2 mixture. It is found that, for 95% of Ar presence in the mixture, the emission intensities from argon and molecular nitrogen are higher, and the emission line intensities will increase nonlinearly. In addition, it is observed that the quenching of Ar* by N2 results in the higher intensities of N2 excited molecules. Moreover, at the higher percentages of Ar in Ar/N2 mixture, while all the plasma temperatures are increased, the plasma electron density is reduced.

  6. Making research data repositories visible: the re3data.org Registry.

    Directory of Open Access Journals (Sweden)

    Heinz Pampel

    Full Text Available Researchers require infrastructures that ensure a maximum of accessibility, stability and reliability to facilitate working with and sharing of research data. Such infrastructures are being increasingly summarized under the term Research Data Repositories (RDR. The project re3data.org-Registry of Research Data Repositories-has begun to index research data repositories in 2012 and offers researchers, funding organizations, libraries and publishers an overview of the heterogeneous research data repository landscape. In July 2013 re3data.org lists 400 research data repositories and counting. 288 of these are described in detail using the re3data.org vocabulary. Information icons help researchers to easily identify an adequate repository for the storage and reuse of their data. This article describes the heterogeneous RDR landscape and presents a typology of institutional, disciplinary, multidisciplinary and project-specific RDR. Further the article outlines the features of re3data.org, and shows how this registry helps to identify appropriate repositories for storage and search of research data.

  7. Making research data repositories visible: the re3data.org Registry.

    Science.gov (United States)

    Pampel, Heinz; Vierkant, Paul; Scholze, Frank; Bertelmann, Roland; Kindling, Maxi; Klump, Jens; Goebelbecker, Hans-Jürgen; Gundlach, Jens; Schirmbacher, Peter; Dierolf, Uwe

    2013-01-01

    Researchers require infrastructures that ensure a maximum of accessibility, stability and reliability to facilitate working with and sharing of research data. Such infrastructures are being increasingly summarized under the term Research Data Repositories (RDR). The project re3data.org-Registry of Research Data Repositories-has begun to index research data repositories in 2012 and offers researchers, funding organizations, libraries and publishers an overview of the heterogeneous research data repository landscape. In July 2013 re3data.org lists 400 research data repositories and counting. 288 of these are described in detail using the re3data.org vocabulary. Information icons help researchers to easily identify an adequate repository for the storage and reuse of their data. This article describes the heterogeneous RDR landscape and presents a typology of institutional, disciplinary, multidisciplinary and project-specific RDR. Further the article outlines the features of re3data.org, and shows how this registry helps to identify appropriate repositories for storage and search of research data.

  8. El Salvador and Guatemala: Security Sector Reform and Political Party System Effects on Organized Crime

    Science.gov (United States)

    2009-06-01

    Labor Unrest and Organized Crime.” September 1995. http://www.envio.org.ni/ articulo /1891 (accessed June 8, 2009). 117 Ibid. 118 Call...Free Market Myth.” June 2005. http://www.envio.org.ni/ articulo /2975 (accessed May 22, 2009). ———. “Labor Unrest and Organized Crime.” September 1995...http://www.envio.org.ni/ articulo /1891 (accessed June 8, 2009). Richani, Nazih. “Systems of Violence and their Political Economy in Post-Conflict

  9. The New Triad. Diffusion, Illusion, and Confusion in the Nuclear Mission

    Science.gov (United States)

    2016-09-01

    Prevention of WMD Proliferation and Terrorism ( New York : Vintage Books , 2008), https://www.absa.org/leg/WorldAtRisk. pdf. and debating the merits and...the Commission on the Prevention of WMD Proliferation and Terrorism. New York : Vintage Books , 2008. https://www.absa.org/leg/WorldAtRisk.pdf. Guthe...Findings of the Nuclear Posture Review , Department of Defense Press Briefing, January  9,  2002, http://www.fas.org/ sgp/ news /2002/01/npr-briefing.html

  10. Improving Statistical Machine Translation Through N-best List Re-ranking and Optimization

    Science.gov (United States)

    2014-03-27

    Linguistics, Boulder, Colorado, June 2009. URL http://www.aclweb.org/ anthology /N/N09/ N09-1025. [31] Dahlgren, Peter. “The Internet, public spheres, and...Computational Linguis- tics, Prague, Czech Republic, June 2007. URL http://www.aclweb.org/ anthology /W/ W07/W07-0232. [36] Duh, Kevin and Katrin Kirchhoff. “Beyond...Computational Linguistics, Columbus, Ohio, June 2008. URL http://www.aclweb.org/ anthology /P/P08/P08-2010. [37] Felice, Mariano and Lucia Specia

  11. Cultivo de hortaliças no sistema orgânico

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Nogueira Sediyama

    2014-12-01

    Full Text Available As hortaliças são os alimentos que mais se destacam, em artigos científicos e em jornais, quando se trata de contaminação com agrotóxicos. Isso tem levado ao aumento na demanda por produtos orgânicos por parte dos consumidores. Há, então, a necessidade de se desenvolverem tecnologias que viabilizem esses sistemas, atendendo ao consumidor e melhorando a renda dos agricultores, geralmente de base familiar. A produção de hortaliças em sistema orgânico requer tecnologias que respeitem os processos ecológicos, que promovam o aumento da matéria orgânica do solo e que sejam poupadoras de energia. Neste artigo, são discutidas algumas dessas tecnologias e resultados de pesquisas, com foco em produção de mudas, manejo e adubação do solo, adubação verde, rotação de culturas, consórcio de hortaliças, manejo de plantas espontâneas e manejo de pragas e doenças, que são práticas aprovadas pelas normas para produção orgânica e seguem os princípios agroecológicos, que contribuem para a maior eficiência energética dos sistemas produtivos e, em conjunto, para o necessário desenvolvimento do setor de produção de hortaliças orgânicas com base científica.

  12. Acoustic resonance spectroscopy (ARS): ARS300 operations manual, software version 2.01

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-25

    Acoustic Resonance Spectroscopy (ARS) is a nondestructive evaluation technology developed at the Los Alamos National Laboratory. The ARS technique is a fast, safe, and nonintrusive technique that is particularly useful when a large number of objects need to be tested. Any physical object, whether solid, hollow, or fluid filled, has many modes of vibration. These modes of vibration, commonly referred to as the natural resonant modes or resonant frequencies, are determined by the object`s shape, size, and physical properties, such as elastic moduli, speed of sound, and density. If the object is mechanically excited at frequencies corresponding to its characteristic natural vibrational modes, a resonance effect can be observed when small excitation energies produce large amplitude vibrations in the object. At other excitation frequencies, i.e., vibrational response of the object is minimal.

  13. Etching properties of BLT films in CF4/Ar plasma

    International Nuclear Information System (INIS)

    Kim, Dong Pyo; Kim, Kyoung Tae; Kim, Chang Il

    2003-01-01

    CF 4 /Ar plasma mass content and etching rate behavior of BLT thin films were investigated in inductively coupled plasma (ICP) reactor as functions of CF 4 /Ar gas mixing ratio, rf power, and dc bias voltage. The variation of relative volume densities for F and Ar atoms were measured by the optical emission spectroscopy (OES). The etching rate as functions of Ar content showed the maximum of 803 A/min at 80 % Ar addition into CF 4 plasma. The presence of maximum etch rate may be explained by the concurrence of two etching mechanisms such as physical sputtering and chemical reaction. The role of Ar ion bombardment includes destruction of metal (Bi, La, Ti)-O bonds as well as support of chemical reaction of metals with fluorine atoms

  14. Mobile Augmented Reality as a Feature for Self-Oriented, Blended Learning in Medicine: Randomized Controlled Trial.

    Science.gov (United States)

    Noll, Christoph; von Jan, Ute; Raap, Ulrike; Albrecht, Urs-Vito

    2017-09-14

    .33 [SD 1.62]; group B: 1.14 [SD 1.30]). For both groups, descriptively, there were only small variations regarding emotional involvement, and learning experiences also differed little, with both groups rating the app similar for its stimulating effect. We were unable to show significant effects for mAR on the immediate learning success of the mobile learning setting. However, the similar level of stimulation being noted for both groups is inconsistent with the previous assumption of the success of mAR-based approach being solely attributable to the excitement of using mobile technology, independent of mAR; the mAR group showed some indications for a better long-term retention of knowledge. Further studies are needed to examine this aspect. German Clinical Trials Register (DRKS): 00012980; http://www.drks.de/drks_web/navigate.do? navigationId=trial.HTML&TRIAL_ID=DRKS00012980 (Archived by WebCite at http://www.webcitation.org/ 6tCWoM2Jb). ©Christoph Noll, Ute von Jan, Ulrike Raap, Urs-Vito Albrecht. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 14.09.2017.

  15. VLA radio observations of AR Scorpii

    Science.gov (United States)

    Stanway, E. R.; Marsh, T. R.; Chote, P.; Gänsicke, B. T.; Steeghs, D.; Wheatley, P. J.

    2018-03-01

    Aims: AR Scorpii is unique amongst known white dwarf binaries in showing powerful pulsations extending to radio frequencies. Here we aim to investigate the multi-frequency radio emission of AR Sco in detail, in order to constrain its origin and emission mechanisms. Methods: We present interferometric radio frequency imaging of AR Sco at 1.5, 5 and 9 GHz, analysing the total flux and polarization behaviour of this source at high time resolution (10, 3 and 3 s), across a full 3.6 h orbital period in each band. Results: We find strong modulation of the radio flux on the orbital period and the orbital sideband of the white dwarf's spin period (also known as the "beat" period). This indicates that, like the optical flux, the radio flux arises predominantly from on or near the inner surface of the M-dwarf companion star. The beat-phase pulsations of AR Sco decrease in strength with decreasing frequency. They are strongest at 9 GHz and at an orbital phase 0.5. Unlike the optical emission from this source, radio emission from AR Sco shows weak linear polarization but very strong circular polarization, reaching 30% at an orbital phase 0.8. We infer the probable existence of a non-relativistic cyclotron emission component, which dominates at low radio frequencies. Given the required magnetic fields, this also likely arises from on or near the M-dwarf. A table of the flux time series is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A66

  16. 40Ar/39Ar dating of the Late Cretaceous

    International Nuclear Information System (INIS)

    Gaylor, Jonathan

    2013-01-01

    As part of the wider European GTS Next project, I propose new constraints on the ages of the Late Cretaceous, derived from a multitude of geochronological techniques, and successful stratigraphic interpretations from Canada and Japan. In the Western Canada Sedimentary Basin, we propose a new constraint on the age of the K/Pg boundary in the Red Deer River section (Alberta, Canada). We were able to cyclo-stratigraphically tune sediments in a non-marine, fluvial environment utilising high-resolution proxy records suggesting a 11-12 precession related cyclicity. Assuming the 40 Ar/ 39 Ar method is inter-calibrated with the cyclo-stratigraphy, the apparent age for C29r suggests that the K/Pg boundary falls between eccentricity maxima and minima, yielding an age of the C29r between 65.89 ± 0.08 and 66.30 ± 0.08 Ma. Assuming that the bundle containing the coal horizon represents a precession cycle, the K/Pg boundary is within the analytical uncertainty of the youngest zircon population achieving a revised age for the K/Pg boundary as 65.75 ± 0.06 Ma. The Campanian - Maastrichtian boundary is preserved in the sedimentary succession of the Horseshoe Canyon Formation and has been placed 8 m below Coal nr. 10. Cyclo-stratigraphic studies show that the formation of these depositional sequences (alternations) of all scales are influenced directly by sea-level changes due to precession but more dominated by eccentricity cycles proved in the cyclo-stratigraphic framework and is mainly controlled by sand horizons, which have been related by auto-cyclicity in a dynamic sedimentary setting. Our work shows that the Campanian - Maastrichtian boundary in the Western Canada Sedimentary Basin coincides with 2.5 eccentricity cycles above the youngest zircon age population at the bottom of the section and 4.9 Myr before the Cretaceous - Palaeogene boundary (K/Pg), and thus corresponds to an absolute age of 70.65 ± 0.09 Ma producing an 1.4 Myr younger age than recent published ages

  17. www.kernenergie.de - nuclear power has a German Internet address

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    www.kernenergie.de is the address on the worldwide web under which the German nuclear organizations, Deutsches Atomforum (DAtF), Informationskreis Kernenergie (IK), and Kerntechnische Gesellschaft (KTG) as well as atw - internationale Zeitschrift fuer Kernenergie, and INFORUM can be reached. Extensive sources of information, discussions, on-line dictionaries, computer codes, dynamic web pages, digital documents and multimedia offerings can be called up via the portal under the individual web sites. In this way, www.kernenergie.de provides a comprehensive and up-to-date background of information about nuclear power and adjacent topics in the digital worldwide web. (orig.) [de

  18. Arthritis - resources

    Science.gov (United States)

    Resources - arthritis ... The following organizations provide more information on arthritis : American Academy of Orthopaedic Surgeons -- orthoinfo.aaos.org/menus/arthritis.cfm Arthritis Foundation -- www.arthritis.org Centers for Disease Control and Prevention -- www. ...

  19. Diabetes - resources

    Science.gov (United States)

    Resources - diabetes ... The following sites provide further information on diabetes: American Diabetes Association -- www.diabetes.org Juvenile Diabetes Research Foundation International -- www.jdrf.org National Center for Chronic Disease Prevention and Health Promotion -- ...

  20. Materia orgánica del suelo: papel de las enmiendas orgánica

    OpenAIRE

    Cabrera, Francisco

    2009-01-01

    El suelo es una mezcla de sólidos orgánicos e inorgánicos, de aire, de agua y de microorganismos. Estas cuatro fases están interrelacionadas entre sí, de forma que: 1) las reacciones entre los componentes de la fase sólida afectan a la composición del agua y del aire del suelo; 2) el aire y el agua del suelo meteorizan los componentes de la fase sólida; 3) los microorganismos del suelo catalizan muchas de las reacciones que tienen lugar en el suelo (Bohn et al. 1979).

  1. Argon in hornblende, biotite and muscovite in geologic cooling - Ar-40/Ar-39-investigations

    International Nuclear Information System (INIS)

    Rittman, K.L.

    1984-01-01

    The results of the Ar-40/Ar-39 studies are discussed under the aspect of whether the age data of the minerals indicate a cooling process. The author hopes that isotope dating of minerals with different closing temperatures will describe the temperature/time history of an area in the temperature range of 600 to 200 0 C. The findings are analyzed under three aspects: How much do they contribute to the initial methodological question, what do they contribute to the regional geology of the areas investigated, and in what respects do they extent the present knowledge of the geochronological analysis, i.e. its techniques and interpretation. (orig.) [de

  2. alpha-MSH and Org.2766 in peripheral nerve regeneration: different routes of delivery.

    Science.gov (United States)

    Van der Zee, C E; Brakkee, J H; Gispen, W H

    1988-03-15

    The efficacy of melanocortins (alpha-MSH and an ACTH-(4-9) analog, Org.2766) in accelerating functional recovery from sciatic nerve damage following various types of subcutaneous and oral administration was assessed in the rat. Furthermore, the effectiveness of the local delivery of melanocortins to the site of injury was examined. An accelerated recovery was evident following subcutaneous constant delivery of Org.2766 from an osmotic mini-pump and from biodegradable polymere microspheres, and was as effective as repeated subcutaneous injections of alpha-MSH or Org.2766. Oral administration of Org.2766 was ineffective. Local application of Org.2766, achieved by wrapping a peptide-impregnated biodegradable gelatine foam matrix around the site of injury, facilitated recovery as well. The biodegradable microspheres and gelatine foam matrix may be of importance in eventual clinical use as effective vehicles for administration of melanocortins in the treatment of peripheral nerve damage.

  3. 40Ar/39Ar laster fusion and K-Ar ages from Lathrop Wells, Nevada, and Cima, California: The age of the latest volcanic activity in the Yucca Mountain area

    International Nuclear Information System (INIS)

    Turrin, B.D.; Champion, D.E.

    1991-01-01

    K-Ar and 40 Ar/ 39 Ar ages from the Lathrop Wells volcanic center, Nevada, and from the Cima volcanic field, California, indicate that the recently reported 20-ka age estimate for the Lathrop Wells volcanic center is incorrect. Instead, an age of 119 ± 11 to 141 ± 10 ka is indicated for the Lathrop Wells volcanic center. This age corrected is concordant with the ages determined by two independent isotopic geochronometric techniques and with the stratigraphy of surficial deposits in the Yucca Mountain region. In addition, paleomagnetic data and radiometric age data indicate only two volcanic events at the Lathrop Wells volcanic center that are probably closely linked in time, not as many as five as recently reported. 32 refs., 2 figs., 2 tabs

  4. GreatSchools.org Finds Its Niche

    Science.gov (United States)

    Samuels, Christina A.

    2012-01-01

    GreatSchools.org neatly ranks more than 136,000 traditional public, private, and charter schools nationwide on a scale of 1 to 10, based on state test scores. But what often draws readers are the gossipy insider comments posted by parents, students, and teachers, and the star ratings those commenters contribute. The growth of online school rating…

  5. myPhyloDB: a local web server for the storage and analysis of metagenomic data.

    Science.gov (United States)

    Manter, Daniel K; Korsa, Matthew; Tebbe, Caleb; Delgado, Jorge A

    2016-01-01

    myPhyloDB v.1.1.2 is a user-friendly personal database with a browser-interface designed to facilitate the storage, processing, analysis, and distribution of microbial community populations (e.g. 16S metagenomics data). MyPhyloDB archives raw sequencing files, and allows for easy selection of project(s)/sample(s) of any combination from all available data in the database. The data processing capabilities of myPhyloDB are also flexible enough to allow the upload and storage of pre-processed data, or use the built-in Mothur pipeline to automate the processing of raw sequencing data. myPhyloDB provides several analytical (e.g. analysis of covariance,t-tests, linear regression, differential abundance (DESeq2), and principal coordinates analysis (PCoA)) and normalization (rarefaction, DESeq2, and proportion) tools for the comparative analysis of taxonomic abundance, species richness and species diversity for projects of various types (e.g. human-associated, human gut microbiome, air, soil, and water) for any taxonomic level(s) desired. Finally, since myPhyloDB is a local web-server, users can quickly distribute data between colleagues and end-users by simply granting others access to their personal myPhyloDB database. myPhyloDB is available athttp://www.ars.usda.gov/services/software/download.htm?softwareid=472 and more information along with tutorials can be found on our websitehttp://www.myphylodb.org. Database URL:http://www.myphylodb.org. Published by Oxford University Press 2016. This work is written by US Government employees and is in the public domain in the United States.

  6. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2010-04-01

    Full Text Available 24th Annual San Diego International Conference on Child and Family Maltreatment January 24, 2010-January 29, 2010 San Diego C, USA URL: http://www.chadwickcenter.org/conference AAFS 62nd Annual Scientific Meeting 22 February 2010-27 February 2010 Putting Our Forensic House in Order: Examining Validation and Expelling Incompetence Seattle, WA 98101 URL: www.aafs.org/default.asp?section_id=meetings&page_id= aafs_annual_meeting 49th Annual Meeting of the US Society of Toxicology (SOT 7 March 2010-11 March 2010 Salt Lake City, Utah, USA URL: www.toxicology.org/AI/MEET/AM2010/ XIXth Mediterranean International Congress of Legal Medicine 7 April 2010-10 April 2010 Tozeur, Tunisia URL: www.aefms.org/j.med.leg.tozeur/jmmlE/index.html ESF-LiU Conference 3 May 2010-7 May 2010 Violations of Human Rights and Humanitarian Law: Investigation and Prevention of Torture and Death in Custody Linköping, Sweden URL: www.esf.org/conferences/10318 7th Annual Meeting Balkan Academy of Forensic Science 03 June 2010-06 June 2010 Tirana, Albania URL: http://www.balkanforensic.org 68th Annual Meeting of the American Society of Questioned Document Examiners (ASQDE 28 September 2010 Victoria, BC, USA URL: www.asqde.org 20th International Symposium on the Forensic Sciences (ANZFSS 5 September 2010-9 September 2010 Sydney, Australia URL: www.anzfss2010.com 10th Indo Pacific Congress on Legal Medicine and Forensic Science 25 - 30 October 2010 New Delhi, India E-mail : p kchatt op adhyay@amity.edu National Association of Medical Examiners 44th Annual Meeting 1 October 2010-6 October 2010 Cleveland, OH. USA URL: www.thename.org 46. Ulusal Psikiyatri Kongresi 5\tEkim 2010-9 Ekim 2010 İzmir, Türkiye URL: http://www.psikiyatri2010.org/ 9. Adli Bilimler Kongresi 14 Ekim 2010-17 Ekim 2010 İzmir, Türkiye http://www.atud.org/ EuroForensics: Digital & Medical Forensic Sciences Conference and Exhibition March 24, 2011-March 26, 2011 Istanbul, Turkey URL: http ://www

  7. 46 CFR 193.01-3 - Incorporation by reference.

    Science.gov (United States)

    2010-10-01

    ... http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, it is... Conshohocken, PA 19428-2959, telephone 610-832-9585, http://www.astm.org. (1) ASTM F 1121-87 (1993), Standard... Park, Quincy, MA 02269-9101, telephone 800-344-3555, http://www.nfpa.org. (1) NFPA 13-1996, Standard...

  8. 46 CFR 95.01-2 - Incorporation by reference.

    Science.gov (United States)

    2010-10-01

    ... http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, it is..., PA 19428-2959, telephone 610-832-9585, http://www.astm.org. (1) ASTM F 1121-87 (1993), Standard... Park, Quincy, MA 02269-9101, telephone 800-344-3555, http://www.nfpa.org. (1) NFPA 13-1996, Standard...

  9. 46 CFR 34.01-15 - Incorporation by reference.

    Science.gov (United States)

    2010-10-01

    ... availability of this material at NARA, call 202-741-6030 or go to http://www.archives.gov/federal_register/code..., http://www.astm.org. (1) ASTM F 1121-87 (Reapproved 1993), Standard Specification for International...-9101, telephone 800-344-3555, http://www.nfpa.org. (1) NFPA 13-1996, Standard for the Installation of...

  10. AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

    Science.gov (United States)

    Aceto, Nicola; Bardia, Aditya; Wittner, Ben S; Donaldson, Maria C; O'Keefe, Ryan; Engstrom, Amanda; Bersani, Francesca; Zheng, Yu; Comaills, Valentine; Niederhoffer, Kira; Zhu, Huili; Mackenzie, Olivia; Shioda, Toshi; Sgroi, Dennis; Kapur, Ravi; Ting, David T; Moy, Beverly; Ramaswamy, Sridhar; Toner, Mehmet; Haber, Daniel A; Maheswaran, Shyamala

    2018-04-01

    Molecular drivers underlying bone metastases in human cancer are not well understood, in part due to constraints in bone tissue sampling. Here, RNA sequencing was performed of circulating tumor cells (CTC) isolated from blood samples of women with metastatic estrogen receptor (ER) + breast cancer, comparing cases with progression in bone versus visceral organs. Among the activated cellular pathways in CTCs from bone-predominant breast cancer is androgen receptor (AR) signaling. AR gene expression is evident, as is its constitutively active splice variant AR-v7. AR expression within CTCs is correlated with the duration of treatment with aromatase inhibitors, suggesting that it contributes to acquired resistance to endocrine therapy. In an established breast cancer xenograft model, a bone-tropic derivative displays increased AR expression, whose genetic or pharmacologic suppression reduces metastases to bone but not to lungs. Together, these observations identify AR signaling in CTCs from women with bone-predominant ER + breast cancer, and provide a rationale for testing androgen inhibitors in this subset of patients. Implications: This study highlights a role for the AR in breast cancer bone metastasis, and suggests that therapeutic targeting of the AR may benefit patients with metastatic breast cancer. Mol Cancer Res; 16(4); 720-7. ©2018 AACR . ©2018 American Association for Cancer Research.

  11. Jumps in binomial AR(1) processes

    OpenAIRE

    Weiß , Christian H.

    2009-01-01

    Abstract We consider the binomial AR(1) model for serially dependent processes of binomial counts. After a review of its definition and known properties, we investigate marginal and serial properties of jumps in such processes. Based on these results, we propose the jumps control chart for monitoring a binomial AR(1) process. We show how to evaluate the performance of this control chart and give design recommendations. correspondance: Tel.: +49 931 31 84968; ...

  12. Single-electron capture into Ar+ excited states in Ar2 + Na collision below 12 keV, 1

    International Nuclear Information System (INIS)

    Matsumoto, Atsushi; Tsurubuchi, Seiji; Okuno, Kazuhiko; Ohtani, Shunsuke; Iwai, Tsuruji.

    1979-08-01

    Emission spectra between 2800 and 6000 A have been observed at the ionic energies from 0.2 to 12 keV. Absolute measurements of emission cross-sections have been made for the emission lines coming from ArII excited states at 4 and 8 keV with a crossed-beam technique. Processes of single-electron capture into the ArII 4p- and 4p'-states, with exothermicity of a few eV, take place dominantly (--10 15 cm 2 ), while the endothermic processes producing ArII in the 4d- and 5s-states occur with small cross-sections. Sum of the cross-sections for electron capture into the excited states observed is comparable with the total single-electron capture cross-section estimated from attenuation measurements of ion currents. Possible errors and uncertainties are discussed. (author)

  13. Single-electron capture into Ar+ excited states in Ar2++Na collision below 12 keV, 1

    International Nuclear Information System (INIS)

    Matsumoto, Atsushi; Tsurubuchi, Seiji; Iwai, Tsuruji; Ohtani, Shunsuke; Okuno, Kazuhiko

    1980-01-01

    Emission spectra between 2800 and 6000 A have been observed at the ionic energies from 0.2 to 12 keV. Absolute measurements of emission cross-sections have been made for the emission lines coming from ArII excited states at 4 and 8 keV with a crossed-beam technique. Processes of single-electron capture into the ArII 4p- and 4p'-states, with exothermicity of a few eV, take place dominantly (--10 -15 cm 2 ), while the endothermic processes producing ArII in the 4d- and 5s-states occur with small cross-sections. Sum of the cross-sections for electron capture into the excited states observed is comparable with the total single-electron capture cross-section estimated from attenuation measurements of ion currents. Possible errors and uncertainties are discussed. (author)

  14. Instance-optimality in probability with an www.elsevier.com/xml/xocs/dtd" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.e

    KAUST Repository

    DeVore, Ronald; Petrova, Guergana; Wojtaszczyk, Przemyslaw

    2009-01-01

    measurements in compressed sensing, Found. Comput. Math., in press] who showed this property when η is a normalized Gaussian random variable. We extend this property to more general random variables, including the particular case where η is the Bernoulli random

  15. Instance-optimality in probability with an www.elsevier.com/xml/xocs/dtd" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.e

    KAUST Repository

    DeVore, Ronald

    2009-11-01

    Let Φ (ω), ω ∈ Ω, be a family of n × N random matrices whose entries φ{symbol}i, j are independent realizations of a symmetric, real random variable η with expectation E η = 0 and variance E η2 = 1 / n. Such matrices are used in compressed sensing to encode a vector x ∈ RN by y = Φ x. The information y holds about x is extracted by using a decoder Δ : Rn → RN. The most prominent decoder is the ℓ1-minimization decoder Δ which gives for a given y ∈ Rn the element Δ (y) ∈ RN which has minimal ℓ1-norm among all z ∈ RN with Φ z = y. This paper is interested in properties of the random family Φ (ω) which guarantee that the vector over(x, ̄) : = Δ (Φ x) will with high probability approximate x in ℓ2 N to an accuracy comparable with the best k-term error of approximation in ℓ2 N for the range k ≤ a n / log2 (N / n). This means that for the above range of k, for each signal x ∈ RN, the vector over(x, ̄) : = Δ (Φ x) satisfies{norm of matrix} x - over(x, ̄) {norm of matrix}ℓ2N ≤ C under(inf, z ∈ Σk) {norm of matrix} x - z {norm of matrix}ℓ2N with high probability on the draw of Φ. Here, Σk consists of all vectors with at most k nonzero coordinates. The first result of this type was proved by Wojtaszczyk [P. Wojtaszczyk, Stability and instance optimality for Gaussian measurements in compressed sensing, Found. Comput. Math., in press] who showed this property when η is a normalized Gaussian random variable. We extend this property to more general random variables, including the particular case where η is the Bernoulli random variable which takes the values ± 1 / sqrt(n) with equal probability. The proofs of our results use geometric mapping properties of such random matrices some of which were recently obtained in [A. Litvak, A. Pajor, M. Rudelson, N. Tomczak-Jaegermann, Smallest singular value of random matrices and geometry of random polytopes, Adv. Math. 195 (2005) 491-523]. © 2009 Elsevier Inc. All rights reserved.

  16. Measurements of the 40Ar(n, γ41Ar radiative-capture cross section between 0.4 and 14.8 MeV

    Directory of Open Access Journals (Sweden)

    Megha Bhike

    2014-09-01

    Full Text Available The 40Ar(n, γ41Ar neutron capture cross section has been measured between 0.4 and 14.8 MeV neutron energy using the activation technique. The data are important for estimating backgrounds in argon-based neutrino and dark-matter detectors and in the neutrino-less double-beta decay search GERDA, which uses liquid argon as cooling and shielding medium. For the first time the 40Ar(n, γ41Ar cross section has been measured for neutron energies above 1 MeV. Our results are compared to the evaluation ENDF/B-VII.1 and the calculated prediction TENDL-2013. The latter agrees very well with the present results.

  17. American Association of Physics Teachers - AAPT.org

    Science.gov (United States)

    AAPT.org - American Association of Physics Teachers Skip to content Skip to navigation Skip to local navigation AAPT - American Association of Physics Teachers Go Sign In / Online Services Join ; Competitions Collaborative Projects U.S. Physics Team New Faculty Programs Publications American Journal of

  18. SPARQL-enabled identifier conversion with Identifiers.org.

    Science.gov (United States)

    Wimalaratne, Sarala M; Bolleman, Jerven; Juty, Nick; Katayama, Toshiaki; Dumontier, Michel; Redaschi, Nicole; Le Novère, Nicolas; Hermjakob, Henning; Laibe, Camille

    2015-06-01

    On the semantic web, in life sciences in particular, data is often distributed via multiple resources. Each of these sources is likely to use their own International Resource Identifier for conceptually the same resource or database record. The lack of correspondence between identifiers introduces a barrier when executing federated SPARQL queries across life science data. We introduce a novel SPARQL-based service to enable on-the-fly integration of life science data. This service uses the identifier patterns defined in the Identifiers.org Registry to generate a plurality of identifier variants, which can then be used to match source identifiers with target identifiers. We demonstrate the utility of this identifier integration approach by answering queries across major producers of life science Linked Data. The SPARQL-based identifier conversion service is available without restriction at http://identifiers.org/services/sparql. © The Author 2015. Published by Oxford University Press.

  19. SPARQL-enabled identifier conversion with Identifiers.org

    Science.gov (United States)

    Wimalaratne, Sarala M.; Bolleman, Jerven; Juty, Nick; Katayama, Toshiaki; Dumontier, Michel; Redaschi, Nicole; Le Novère, Nicolas; Hermjakob, Henning; Laibe, Camille

    2015-01-01

    Motivation: On the semantic web, in life sciences in particular, data is often distributed via multiple resources. Each of these sources is likely to use their own International Resource Identifier for conceptually the same resource or database record. The lack of correspondence between identifiers introduces a barrier when executing federated SPARQL queries across life science data. Results: We introduce a novel SPARQL-based service to enable on-the-fly integration of life science data. This service uses the identifier patterns defined in the Identifiers.org Registry to generate a plurality of identifier variants, which can then be used to match source identifiers with target identifiers. We demonstrate the utility of this identifier integration approach by answering queries across major producers of life science Linked Data. Availability and implementation: The SPARQL-based identifier conversion service is available without restriction at http://identifiers.org/services/sparql. Contact: sarala@ebi.ac.uk PMID:25638809

  20. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2010-12-01

    Full Text Available 24th Annual San Diego International Conference on Child and Family Maltreatment January 24, 2010-January 29, 2010 San Diego C, USA URL: http://www.chadwickcenter.org/conference AAFS 62nd Annual Scientific Meeting 22 February 2010-27 February 2010 Putting Our Forensic Flouse in Order: Examining Validation and Expelling Incompetence Seattle, WA 98101 URL: www.aafs.org/default.aspPsection_id = meetings& page_id= aafs_annual_meeting 49th Annual Meeting of the US Society of Toxicology (SOT 7 March 2010-11 March 2010 Salt Lake City, Utah, USA URL: www.toxicology.org/AI/MEET/AM2010/ XIXth Mediterranean International Congress of Legal Medicine 7 April 2010-10 April 2010 Tozeur, Tunisia URL: www.aefms.org/j.med.leg.tozeur/jmml_E/index.html ESF-LiU Conference 3 May 2010-7 May 2010 Violations of Human Rights and Humanitarian Law: Investigation and Prevention of Torture and Death in Custody Linköping, Sweden URL: www.esf.org/conferences/10318 7th Annual Meeting Balkan Academy of Forensic Science 03 June 2010-06 June 2010 Tirana, Albania URL: http://www.balkanforensic.org 68th Annual Meeting of the American Society of Questioned Document Examiners (ASQDE 28 September 2010 Victoria, BC, USA URL: www.asqde.org 20th International Symposium on the Forensic Sciences (ANZFSS 5 September 2010-9 September 2010 Sydney, Australia URL: www.anzfss2010.com Bloodstain Pattern Recognition - Basic course 05 December 2011, 09 December 2011 Tbe Hague, The Netherlands URL: http://www.enfsi.eu/page.php?uid= Expert Witness Intensive Training Course - 2 Day December 8th to 9th 2011 United Kingdom /London URL: http://www.healthcareconferencesuk.co.uk/ expertwitness 6th USA Pacific Medical & Legal Conference December 13th to 20th 2011 New York /USA URL: http://www.conferences21.com/index.php? menu=home 12th Annual Pan Europe Pacific Medical & Legal Conference February 5th to 12th 2012 France /Paris URL: http://www.conferences21.com/index.php? menu=home American College of Legal

  1. Characteristics of violent collisions in Ar-induced reactions at intermediaire energies

    International Nuclear Information System (INIS)

    Rivet, M.F.; Borderie, B.

    1984-01-01

    We report on two experiments performed with the Ganil facility using the 27 MeV/u Ar beam. The first one concerns an intermediate mass system, Ar + Ag. For the second one a heavier fissile system, Ar + U, was chosen. For Ar + Ag information about fusion requires the measurements of evaporation residues and fission. In the Ar + U reaction, most of the collisions lead to fission. The violence of the collision is therefore determined from the correlation angle of the coincidence fission fragments

  2. Levels in 45K and 46K excited by the β decay of 45Ar and 46Ar

    International Nuclear Information System (INIS)

    Huck, A.; Klotz, G.; Knipper, A.; Miehe, C.; Walter, G.

    1979-01-01

    The nuclides 45 Ar and 46 Ar have been produced by spallation reactions on vanadium targets at Esub(p)=600MeV. The subsequent decays to 45 K and 46 K states have been studied. An intensity of 98.6+-0.6% was measured for the β transition of the 1.94MeV state in 46 K. A decay scheme involving 13 β branches has been established for 45 Ar, and the corresponding log values have been deduced. Eleven states are reported for the first time in the decay scheme of 45 Ar 1.42, 1.47, 1.72, 2.52, 2.57, 2.75, 3.31, 3.99, 4.04, 4.36 and 4.57MeV. From the lifetime, tau=4.6+-0.6ns, deduced from γ-γ delayed coincidences, the angular momentum of the 1081keV level has been established as (7/2) - on the basis of the transition strength of its γ decay. A survey on the 1fsub(7/2)→1dsub(3/2)M2 transition in odd K nuclei is presented and the observed hindrance factors are discussed

  3. Sensibility of different wheat varieties (strains) to Ar+ implantation

    International Nuclear Information System (INIS)

    Cui Huanhu; Jing Hua; Ma Aiping; Kang Xiuli; Yang Liping; Huang Mingjing; Ma Buzhou; Shanxi Academy of Agricultural Sciences, Taiyuan

    2005-01-01

    The sensibility of different wheat varieties (strains) to Ar + implantation was studied. The results showed that the survival rate of 21 wheat varieties (strains) at the dose of 6 x 10 16 Ar + /cm 2 could be divided into five groups: surplus sensitive varieties (strains), sensitive varieties (strains), transitional varieties (strains), obtuse varieties (strains) and surplus obtuse varieties (strains). The sensibility of wheat varieties (strains) to Ar + injection is high-moisture-fertility wheat varieties (strains) > medium-moisture-fertility wheat varieties (strains) > dry land wheat varieties (strains). The study has provided theoretical basis in induced mutation medial lethal dose of different wheat varieties (strains) to Ar + implantation. (authors)

  4. AR-v7 protein expression is regulated by protein kinase and phosphatase

    Science.gov (United States)

    Li, Yinan; Xie, Ning; Gleave, Martin E.; Rennie, Paul S.; Dong, Xuesen

    2015-01-01

    Failure of androgen-targeted therapy and progression of castration-resistant prostate cancer (CRPC) are often attributed to sustained expression of the androgen receptor (AR) and its major splice variant, AR-v7. Although the new generation of anti-androgens such as enzalutamide effectively inhibits AR activity, accumulating pre-clinical and clinical evidence indicates that AR-v7 remains constitutively active in driving CRPC progression. However, molecular mechanisms which control AR-v7 protein expression remain unclear. We apply multiple prostate cancer cell models to demonstrate that enzalutamide induces differential activation of protein phosphatase-1 (PP-1) and Akt kinase depending on the gene context of cancer cells. The balance between PP-1 and Akt activation governs AR phosphorylation status and activation of the Mdm2 ubiquitin ligase. Mdm2 recognizes phosphorylated serine 213 of AR-v7, and induces AR-v7 ubiquitination and protein degradation. These findings highlight the decisive roles of PP-1 and Akt for AR-v7 protein expression and activities when AR is functionally blocked. PMID:26378044

  5. Dating quartz: Ar/Ar analyses of coexisting muscovite and fluid inclusion - rich quartz from paleocene amorphic aureole

    International Nuclear Information System (INIS)

    Matthews, S.J.; Perez de Arce, C.; Cornejo, P.; Cuitino, L; Klein, J

    2001-01-01

    We present Ar/Ar total fusion and step-heating data for coexisting muscovite and white quartz from the metamorphic aureole of the Lower Paleocene La Copiapina Pluton, 6 km south of Inca de Oro, III Region, Chile. The pluton intrudes the upper clastic sedimentary member of the Punta del Cobre Group (Upper Jurassic - Lower Cretaceous) and the calcareous sedimentary rocks of the Chanarcillo Group (Neocomian), and comprises fine to coarse grained pyroxene-hornblende-biotite quartz diorites and monzodiorites. Its emplacement was controlled on its north-western side by a subvertical NE-trending fault, along which were developed vertically banded skarns (skarn mylonite), suggesting syntectonic intrusion. Biotite K-Ar ages for the pluton fall in the range 61-63 Ma, relating it to a latest Cretaceous to Lowest Paleocene syn-compressional intrusive belt which is present in the area (Matthews and Cornejo, 2000). A metamorphic / metasomatic aureole is developed within the sandstones of the Punta del Cobre Group, on the extreme northern limit of the pluton. In this area, the sedimentary rocks have been replaced by quartz-sericite and quartz-muscovite assemblages, with minor hematite and tourmaline, and late supergene kaolinite and pyrophyllite. A coarse muscovite-quartz-tourmaline-hematite assemblage is developed in and around older (early Upper Cretaceous) andesitic dykes, in the form of replacement / fracture fill veins and replacement zones. Further from the contact with the pluton, fine-grained quartz-sericite rock with coarser muscovite-rich replacement veins represents the dominant lithology. Quartz in the coarse replacement rock is very rich in fluid inclusions. Primary inclusions are mainly of two coexisting types; bi-phase (liquid and gas bubble) and tri-phase (liquid, gas bubble and halite crystal), indicating that the quartz formed in the presence of a boiling fluid. Some inclusions also contain sylvite and occasional hematite daughter crystals. Secondary inclusions

  6. 75 FR 68416 - Establishment of Class E Airspace; Berryville, AR

    Science.gov (United States)

    2010-11-08

    ...-0690; Airspace Docket No. 10-ASW-2] Establishment of Class E Airspace; Berryville, AR AGENCY: Federal... for Berryville, AR, to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAP) at Carroll County Airport, Berryville, AR. The FAA is taking this action to enhance the safety...

  7. 76 FR 73505 - Establishment of Class E Airspace; Nashville, AR

    Science.gov (United States)

    2011-11-29

    ...-0497; Airspace Docket No. 11-ASW-4] Establishment of Class E Airspace; Nashville, AR AGENCY: Federal... for Nashville, AR, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures... a notice of proposed rulemaking to amend Class E airspace for Nashville, AR, creating additional...

  8. 75 FR 29655 - Amendment of Class E Airspace; Batesville, AR

    Science.gov (United States)

    2010-05-27

    ...-1177; Airspace Docket No. 09-ASW-34] Amendment of Class E Airspace; Batesville, AR AGENCY: Federal... Batesville, AR. Decommissioning of the Independence County non-directional beacon (NDB) at Batesville Regional Airport, Batesville, AR, has made this action necessary to enhance the safety and management of...

  9. Influence of Ar addition on ozone generation in nonthermal plasmas

    International Nuclear Information System (INIS)

    Chen, Hsin Liang; Lee, How Ming; Chen, Shiaw Huei; Wei, Ta Chin; Chang, Moo Been

    2010-01-01

    Inconsistency regarding the influence of Ar addition on ozone generation in a corona discharge has been found in relevant studies. Unlike in the literature to date, a dielectric barrier discharge (DBD) reactor is adopted in this study. In addition to clarifying whether using Ar as an additive would lead to different types of behavior in a DBD and a corona discharge, this study is also motivated to explore the possible causes leading to the inconsistency. The experimental results show that adding Ar into the O 2 plasma would lead to the same influence on ozone generation in the DBD and corona discharge. Moreover, all types of controversial behavior caused by Ar addition reported in the relevant literature are observed in this study as well, indicating that the results of this study are comprehensive enough to interpret the inconsistency. By examining the experimental results in detail, it is found that the controversial influences of Ar addition on ozone generation were found using different assumptions. At a fixed applied voltage, the ozone generation might increase as the Ar concentration is increased, which results from a higher discharge power. Nevertheless, for a certain specific input energy (the ratio of discharge power to gas flow rate), the ozone concentration is lower as the Ar concentration is increased. Therefore, adding Ar is not a good way to enhance ozone generation from an economic point of view.

  10. Contribution of the 40Ar/39Ar method to improve Middle-Pleistocene archaeological/palaeontological sites from the Italian Peninsula

    Science.gov (United States)

    Nomade, Sebastien, ,, Dr.; Pereira, MSc. Alison; voinchet, Pierre, ,, Dr.; Bahain, Jean-Jacques, ,, Dr.; Aureli, Daniele, ,, Dr.; Arzarello, Marta, ,, Dr.; Anzidei, Anna-Paola, ,, Dr.; Biddittu, Italo, ,, Dr.; Bulgarelli, Maria-Grazia, ,, Dr.; Falguères, Christophe, ,, Dr.; Giaccio, Biagio, ,, Dr.; Guillou, Hervé, ,, Dr.; Manzi, Gorgio, ,, Dr.; Moncel, Marie-Hélène, ,, Dr.; Nicoud, Elisa, ,, Dr.; Pagli, Maria, ,, Dr.; Parenti, Fabio, ,, Dr.; Peretto, Carlo, ,, Dr.; Piperno, Marcello, ,, Dr.; Rocca, Roxane, ,, Dr.

    2017-04-01

    European Middle-Pleistocene archaeological and/or paleontological sites lack a unified and precise chronological framework. Despite recent efforts mostly focused on methods such as OSL, ESR/U-series or cosmogenic nuclides, the age of numerous sites from this period fundamentally still relies on qualitative and speculative palaeoenvironmental and/or palaeontological/palaeoanthropological considerations. The lack of robust chronologies, along with the scarcity of human fossils, prevent coherent correlations between European sites which in turn limits our understanding of human diffusion dynamics, understand techno-cultural evolution or correlate archaeological sites with palaeoclimatic and environmental records. With the goal of providing an accurate and precise chronological framework based on a multi-method approach, a research network including geochronologists, archaeologist and paleoanthropologists from various French and Italian institutions launched in 2010 a wide study of Middle-Pleistocene archaeological sites of central and southern Italy. This study combining the 39Ar/40Ar method with palaeo-dosimetric methods applied to European sites in the age range of 700 ka to 300 ka is unprecedented. In parallel, a large effort has been done to improve the regional Middle-Pleistocene tephrostratigraphic database through a massive application of both high-precision 40Ar/39Ar geochronological and geochemical investigations. We illustrate our approach and results in addressing several key-sites such as Notarchirico, Valle Giumentina; Ceprano-Campogrande and La Polledrara di Cecanibbio. The accurate and precise chronological framework we built permits us to replace all the investigated archaeological and palaeontological records into a coherent climatic and environmental context. Furthermore, our work provides the opportunity to compare lithic industries from a technical and evolutionary point of view within a homogeneous temporal frame. These preliminary results border

  11. Problems in the K-Ar dating of Quaternary volcanic rocks younger than 1 Ma

    International Nuclear Information System (INIS)

    Takaoka, Nobuo

    1989-01-01

    The assumption that the 40 Ar/ 36 Ar ratio of Ar trapped in volcanic rocks at eruption is atmospheric often gives a large systematic error in the K-Ar dating of Quaternary volcanic rocks younger than 1 Ma. There are two possible sources of error, the existence of excess Ar and mass-fractionated, initial Ar. The major source of excess Ar is supposed to be magma. The 40 Ar/ 36 Ar ratio for magmatic Ar in the North-East Japan arc is tentatively estimated to be 340±10 from measurements of Ar in large phenocrysts separated from Quaternary volcanic rocks. Separation of phenocrysts is the most effective to decrease the systematic error caused by excess Ar. The mass-fractionation of initial Ar should give the 38 Ar/ 36 Ar ratio which was changed from the atmospheric ratio. This can be checked by determining the 38 Ar/ 36 Ar ratio in samples. Since the systematic error caused by the mass-fractionated, initial Ar increases greatly with the increasing atmospheric Ar correction, it is important to correct the result for the mass-fractionation. Correction formulae are given. The error sources other than those mentioned above are uncertainty in the blank correction and instabilities in the sensitivity of spectrometer and the Ar isotopic ratio measurement. In order to increase accuracy of the K-Ar age obtained, to check the systematic errors by measuring samples together with standard samples is of great importance in the K-Ar dating of very young volcanic rocks. (author)

  12. arXiv ARS Leptogenesis

    CERN Document Server

    Drewes, M.; Hernandez, P.; Kekic, M.; Lopez-Pavon, J.; Racker, J.; Rius, N.; Salvado, J.; Teresi, D.

    2018-02-28

    We review the current status of the leptogenesis scenario originally proposed by Akhmedov, Rubakov and Smirnov (ARS). It takes place in the parametric regime where the right-handed neutrinos are at the electroweak scale or below and the CP-violating effects are induced by the coherent superposition of different right-handed mass eigenstates. Two main theoretical approaches to derive quantum kinetic equations, the Hamiltonian time evolution as well as the Closed-Time-Path technique are presented, and we discuss their relations. For scenarios with two right-handed neutrinos, we chart the viable parameter space. Both, a Bayesian analysis, that determines the most likely configurations for viable leptogenesis given different variants of flat priors, and a determination of the maximally allowed mixing between the light, mostly left-handed, and heavy, mostly right-handed, neutrino states are discussed. Rephasing invariants are shown to be a useful tool to classify and to understand various distinct contributions to...

  13. 40Ar/39Ar incremental-release ages of biotite from a progressively remetamorphosed Archean basement terrane in southwestern Labrador

    International Nuclear Information System (INIS)

    Dallmeyer, R.D.

    1982-01-01

    Gneisses within Archean basement terrane adjacent to the southwestern portion of the Labrador Trough were variably retrograded during a regional metamorphism of Grenville age (ca. 1000 Ma). Bioties from non-retrograded segments of the gneiss terrane record 40 Ar/ 39 Ar plateau and isochron ages which date times of cooling following an episode of the Kenoran orogeny (2376-2391 Ma). A suite of gneiss samples displaying varying degrees of retrograde alteration was collected across the Grenville metamorphic gradient. Bioties in these samples show no petrographic evidence of retrograde alteration, however they do record internally discordant 40 Ar/ 39 Ar age spectra. Although the extent of internal discordance is variable, the overall character of the release patterns is similar with younger apparent ages recorded in intermediate-temperature gas fractions. The total-gas dates range from 2257+-27 Ma (northwest) to 1751+-23 Ma (southeast), suggesting that variable quantities of radiogenic argon were lost from the Archean biotites during Grenville metamorphism. The 'saddle-shaped' nature of the discordant spectra indicates that argon loss was not accomplished through single-stage, volume diffusion processes. (orig./ME)

  14. Ar-40/Ar-39 age determinations for the Rotoiti eruption, New Zealand

    Science.gov (United States)

    Flude, S.; Storey, M.

    2013-12-01

    The contemporaneous Rotoiti and Earthquake Flat ignimbrites, erupted from the Taupo Volcanic zone, New Zealand, form a distinctive tephrostratigraphic horizon in the Southern Pacific. Radioisotopic dating results for these eruptions remain controversial, with published ages ranging from 35.1 × 2.8 ka [1] to 71 × 6 ka [2], with 61.0 × 1.5 ka [3] often being cited as the most widely accepted age. These eruptions are difficult to date as their age is near the limit for various radiometric dating techniques, which are complicated by a large proportion of inherited material (xenocrysts) and a lack of phases suitable for dating. Glass-bearing plutonic blocks erupted with the Rotoiti and Earthquake Flat ignimbrites have previously been interpreted as deriving from a slowly cooled and incompletely solidified magma body that was sampled by the eruptions. They contain large vugs lined with euhedral quartz, sanidine and biotite crystals, indicating that these crystals grew in a gas or aqueous fluid rich environment and are interpreted to have formed shortly before or during eruption. Here we will present Ar-40/Ar-39 ages for sanidines and biotites extracted from vugs in lithic blocks erupted as part of the Earthquake Flat ignimbrite. We show that, even for vug-lining material, inherited ages remain a problem and are the likely source of the wide variation in published radiometric ages. Nevertheless, many of the Ar-40/Ar-39 ages are much younger than the 61 ka age [3] and are more consistent with the recent stratigraphic, C-14 and U-238/Th-230+(U-Th)/He ages that have been suggested (e.g. [4,5]). 1. Whitehead, N. & Ditchburn, R. New Zealand Journal of Geology and Geophysics 37, 381-383 (1994). 2. Ota, Y., Omura, A. & Iwata, H. New Zealand Journal of Geology and Geophysics 32, 327-331 (1989). 3. Wilson, C. J. N. et al. Quaternary Science Reviews 26, 1861-1870 (2007). 4. Molloy, C., Shane, P. & Augustinus, P. Geological Society of America Bulletin 121, 1666-1677 (2009). 5

  15. http://www.bioline.org.br/js 124 Ageing and its Effect on the ...

    African Journals Online (AJOL)

    jen

    lymphoblasts decreased with age while the medulla and lymphocytes increased. The fat content of the gland increased with age. The study showed a positive correlation of weight of the glands with age from birth to puberty, later the correlation becomes negative. There is a decrease in the activity of the gland as shown by ...

  16. Software Engineering and eLearning: The MuSofT Project - www.musoft.org

    Directory of Open Access Journals (Sweden)

    Ernst-Erich Doberkat

    2005-12-01

    Full Text Available eLearning supports the education in certain disciplines. Here, we report about novel eLearning concepts, techniques, and tools to support education in Software Engineering, a subdiscipline of computer science. We call this "Software Engineering eLearning". On the other side, software support is a substantial prerequisite for eLearning in any discipline. Thus, Software Engineering techniques have to be applied to develop and maintain those software systems. We call this "eLearning Software Engineering". Both aspects have been investigated in a large joint, BMBF-funded research project, termed MuSofT (Multimedia in Software Engineering. The main results are summarized in this paper.

  17. 78 FR 41838 - Establishment of Class E Airspace; Colt, AR

    Science.gov (United States)

    2013-07-12

    ...-1281; Airspace Docket No. 12-ASW-13] Establishment of Class E Airspace; Colt, AR AGENCY: Federal... at Colt, AR. Controlled airspace is necessary to accommodate new Area Navigation (RNAV) Standard... Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace for the Colt, AR...

  18. 75 FR 29657 - Establishment of Class E Airspace; Marianna, AR

    Science.gov (United States)

    2010-05-27

    ...-1167; Airspace Docket No. 09-ASW-33] Establishment of Class E Airspace; Marianna, AR AGENCY: Federal... for Marianna, AR to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAPs) at Marianna/Lee County Airport--Steve Edwards Field, Marianna, AR. The FAA is taking this action to...

  19. 75 FR 29656 - Amendment of Class E Airspace; Magnolia, AR

    Science.gov (United States)

    2010-05-27

    ...-1179; Airspace Docket No. 09-ASW-35] Amendment of Class E Airspace; Magnolia, AR AGENCY: Federal... airspace for Magnolia, AR. Decommissioning of the Magnolia non-directional beacon (NDB) at Magnolia Municipal Airport, Magnolia, AR has made this action necessary to enhance the safety and management of...

  20. 75 FR 37291 - Amendment of Class E Airspace; Osceola, AR

    Science.gov (United States)

    2010-06-29

    ...-1183; Airspace Docket No. 09-ASW-38] Amendment of Class E Airspace; Osceola, AR AGENCY: Federal... Osceola, AR. Decommissioning of the Osceola non-directional beacon (NDB) at Osceola Municipal Airport has... rulemaking to amend Class E airspace for Osceola, AR, reconfiguring controlled airspace at Osceola Municipal...

  1. Science Academies' Summer Research Fellowship Programme for ...

    Indian Academy of Sciences (India)

    IAS Admin

    2015-09-10

    Sep 10, 2015 ... A copy of the application format, instructions to applicants including eligibility criteria, and a list of names of scientists/faculty who have consented to guide students/ teachers to work on short-term projects is displayed at the websites of the Academies [www.ias.ac.in; www.insaindia.org and www.nasi.org.in].

  2. Exhumation history of the NW Indian Himalaya revealed by fission track and 40Ar/39Ar ages

    Science.gov (United States)

    Schlup, Micha; Steck, Albrecht; Carter, Andrew; Cosca, Michael; Epard, Jean-Luc; Hunziker, Johannes

    2011-01-01

    New fission track and Ar/Ar geochronological data provide time constraints on the exhumation history of the Himalayan nappes in the Mandi (Beas valley) — Tso Morari transect of the NW Indian Himalaya. Results from this and previous studies suggest that the SW-directed North Himalayan nappes were emplaced by detachment from the underthrusted upper Indian crust by 55 Ma and metamorphosed by ca. 48–40 Ma. The nappe stack was subsequently exhumed to shallow upper crustal depths (

  3. Absolute timing of sulfide and gold mineralization: A comparison of Re-Os molybdenite and Ar-Ar mica methods from the Tintina Gold Belt, Alaska

    Science.gov (United States)

    Selby, D.; Creaser, R.A.; Hart, C.J.R.; Rombach, C.S.; Thompson, J.F.H.; Smith, Moira T.; Bakke, A.A.; Goldfarb, R.J.

    2002-01-01

    New Re-Os molybdenite dates from two lode gold deposits of the Tintina Gold Belt, Alaska, provide direct timing constraints for sulfide and gold mineralization. At Fort Knox, the Re-Os molybdenite date is identical to the U-Pb zircon age for the host intrusion, supporting an intrusive-related origin for the deposit. However, 40Ar/39Ar dates from hydrothermal and igneous mica are considerably younger. At the Pogo deposit, Re-Os molybdenite dates are also much older than 40Ar/39Ar dates from hydrothermal mica, but dissimilar to the age of local granites. These age relationships indicate that the Re-Os molybdenite method records the timing of sulfide and gold mineralization, whereas much younger 40Ar/39Ar dates are affected by post-ore thermal events, slow cooling, and/or systemic analytical effects. The results of this study complement a growing body of evidence to indicate that the Re-Os chronometer in molybdenite can be an accurate and robust tool for establishing timing relations in ore systems.

  4. Indian Academy of Sciences, Bangalore Indian National Science ...

    Indian Academy of Sciences (India)

    2009-09-30

    .in),. (www.insaindia.org) or (www.nasi.org.in); however a copy of the application together with enclosures must be sent by post to The Coordinator, Science Education Programme, Indian. Academy of Sciences, C.V. Raman ...

  5. Thrombin Time

    Science.gov (United States)

    ... information]. Available online at http://www2.massgeneral.org/pathology/coagbook/CO004600.htm through http://www2.massgeneral.org . Accessed July 2010. Dugdale, D. (Updated 2009 March 2). Congenital afibrinogenemia. MedlinePlus Medical Encyclopedia [On-line ...

  6. 75 FR 12161 - Establishment of Class E Airspace; Marianna, AR

    Science.gov (United States)

    2010-03-15

    ...-1167; Airspace Docket No. 09-ASW-33] Establishment of Class E Airspace; Marianna, AR AGENCY: Federal... proposes to establish Class E airspace at Marianna/Lee County Airport-Steve Edwards Field, Marianna, AR, to... operations at Marianna/Lee County Airport-Steve Edwards Field, Marianna, AR. Controlled airspace is needed...

  7. Financement de base à l'intention de la Fondation telecentre.org ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Financement de base à l'intention de la Fondation telecentre.org. Alors qu'il était hébergé au CRDI, le programme telecentre.org a eu des répercussions majeures sur la capacité organisationnelle (compétences en gestion, capacité de réseautage et développement du leadership), la diffusion des connaissances et la ...

  8. Potential hydroxyl ultraviolet laser. [Ar-H/sub 2/O

    Energy Technology Data Exchange (ETDEWEB)

    Chen, C H; Payne, M G

    1976-09-01

    A strong emission band extending from 3060 to 3120 A was observed following proton beam excitation of an Ar--H/sub 2/O mixture. This emission band was assigned to the transition of OH(A/sup 2/Sigma/sup +/)/sub nu=o/ ..-->.. OH(X/sup 2/Pi)/sub nu=o/. At high argon partial pressure (> 200 torr), the precursor of this emission band is believed to be the argon excimer Ar/sup *//sub 2/(1/sub u/). The fluorescence efficiency of Ar--H/sub 2/O is estimated to be a factor of 4 times that of Ar--N/sub 2/. Development of a highly efficient, tunable uv laser by e-beam pumping is promising.

  9. A phase one AR/C system design

    Science.gov (United States)

    Kachmar, Peter M.; Polutchko, Robert J.; Matusky, Martin; Chu, William; Jackson, William; Montez, Moises

    1991-01-01

    The Phase One AR&C System Design integrates an evolutionary design based on the legacy of previous mission successes, flight tested components from manned Rendezvous and Proximity Operations (RPO) space programs, and additional AR&C components validated using proven methods. The Phase One system has a modular, open architecture with the standardized interfaces proposed for Space Station Freedom system architecture.

  10. The beta decay asymmetry parameter of 35Ar

    International Nuclear Information System (INIS)

    Garnett, J.D.

    1987-11-01

    The beta decay asymmetry parameter for 35 Ar = 35 Cl + e + + nu/sub e/ has been remeasured in order to resolve a long standing puzzle. Previous asymmetry measurements, when combined with the comparative half-life, yield a value for the vector coupling constant, G/sub v/, that is in serious disagreement with the accepted value. We produced polarized 35 Ar by a (p,n) reaction on 35 Cl using the polarized proton beam provided by Lawrence Berkeley Laboratory's 88-Inch Cyclotron. The polarization of the 35 Ar was determined by measuring the asymmetry of the positrons produced in 35 Ar decay to the first excited state in 35 Cl (branching ratio = 1.3%) in coincidence with a 1219.4 keV gamma ray. Our result, A 0 = 0.49 +- 0.10, combined with the comparative half-life yields a value for G/sub v/ in agreement with the accepted value

  11. Geochemistry and 40Ar/39Ar age of Early Carboniferous dolerite sills in the southern Baltic Sea

    Directory of Open Access Journals (Sweden)

    Gediminas Motuza

    2015-08-01

    Full Text Available The Early Carboniferous magmatic event in the southern Baltic Sea is manifested by dolerite intrusions. The presumable area in which the dolerite intrusions occur ranges from 30 to 60 km in east–west direction, and is about 100 km in north–south direction. The dolerites were sampled in well D1-1 and investigated by applying chemical analysis and 40Ar/39Ar step-heating dating. Dolerites are classified as alkali and sodic, characterized by high TiO2 (3.92, 3.99 wt% and P2O5 (1.67, 1.77 wt% and low MgO (4.89, 4.91 wt% concentrations, enriched in light rare earth elements, originated from an enriched mantle magma source and emplaced in a continental rift tectonic setting. The 351 ± 11 Ma 40Ar/39Ar plateau age for groundmass plagioclase indicates a considerable age gap with the 310–250 Ma magmatism in southern Scandinavia and northern Germany. The magmatic rocks in the Baltic Sedimentary Basin are coeval with alkaline intrusions of NE Poland. Both magmatic provinces lie in the northwestward prolongation of the Pripyat–Dnieper–Donetsk Rift (370–359 Ma and may constitute a later phase of magmatic activity of this propagating rift system.

  12. Ar-Ar Ages of Nakhlites Y000593, NWA998, and Nakhla and CRE Age of NWA998.

    Science.gov (United States)

    Garrison, D. H.; Bogard, D. D.

    2006-01-01

    The seven known Martian nakhlites are Nakhla, Lafayette, Governador Valadares, and four recent finds from hot and cold deserts: MIL03346 from the Transantarctic Mountains, a paired group from the Yamato Mountains (Y000593, Y000749, and Y000802; 1), and two from Morocco (NWA998 and NWA817; 2). Radiometric ages (Sm-Nd, Rb-Sr, U-Pb, and Ar-Ar) for the first three nakhlites, along with Chassigny, fall in the range of 1.19-1.37 Gyr and may suggest a common formation age (e.g., 3). These meteorites also show very similar cosmic-ray (space) exposure ages, which suggests a single ejection event from Mars (3). The ages for nakhlites are different from those of Martian shergottites, whose radiometric ages vary by nearly a factor of three (approximately 165-475 Myr) and whose space exposure ages vary over a factor of approximately 20 (3). Shergottite ages suggest that multiple locations on the Martian surface have been sampled, whereas nakhlite data imply that only one Mars surface location has been sampled. Because older Martian surfaces are expected to be more abundant, it seems surprising that all nakhlites would represent only one Martian impact event. To address this issue, we are measuring the Ar-39-Ar-40 ages of Y-000593, NWA-998, Nakhla, and MIL-03346, and the space (CRE) exposure age of NWA998.

  13. Ar-Ar Ages of Nakhlites Y000593, NWA998, and Nakhla and CRE Ages of NWA998

    Science.gov (United States)

    Garrison, D. H.; Bogard, D. D.

    2005-01-01

    The seven known Martian nakhlites are Nakhla, Lafayette, Governador Valadares, and four recent finds from hot and cold deserts: MIL03346 from the Transantarctic Mountains, a paired group from the Yamato Mountains (Y000593, Y000749, and Y000802, and two from Morocco (NWA998 and NWA817. Radiometric ages (Sm-Nd, Rb-Sr, U-Pb, and Ar-Ar) for the first three nakhlites, along with Chassigny, fall in the range of 1.19-1.37 Gyr and may suggest a common formation age. These meteorites also show very similar cosmic-ray (space) exposure ages, suggesting a single ejection event from Mars. The ages for nakhlites are different from those of Martian shergottites, whose radiometric ages vary by nearly a factor of three (approx. 165-475 Myr) and whose space exposure ages vary over a factor of approx. 20. Shergottite ages suggest that multiple locations on the Martian surface have been sampled, whereas nakhlite data imply sampling of only one Mars surface location. Because older Martian surfaces are expected to be more abundant, it seems surprising that all nakhlites would represent only one Martian impact event. To address this issue, we are measuring the (39)Ar-(40)Ar ages of Y-000593, NWA-998, Nakhla, and MIL-03346, and the space (CRE) exposure age of NWA998. Additional information is included in the original extended abstract.

  14. Timing and processes for exhumation of HP/LT rocks of the southern Brooks Range (AK): Insight from combined geochemistry and 40Ar/39Ar thermochronology of white mica

    Science.gov (United States)

    O'Brien, T.; Miller, E. L.; Grove, M. J.; Hayden, L. A.

    2015-12-01

    The obduction of an island arc onto the Arctic Alaska continental margin in the Jura-Cretaceous led to southward subduction of continental crust and high-pressure/low-temperature (HP/LT) epidote-blueschist facies metamorphism in the southern Brooks Range (BR). A regionally developed greenschist facies normal-sense shear zone system along the southern margin of the BR suggests that extensional faulting had an influential role in the exhumation of the metamorphic core. To better constrain the exhumation history of the metamorphic core of the BR, samples were collected from a N-S transect through the metamorphic core of the orogen. Electron microprobe (EMP) analyses of white micas reveal that they are composed of phengite (Si > 3.0 pfu) or a combination of phengite + paragonite. Si-content of phengites reveal a southward increase in Si from 3.1 to 3.4 pfu (corresponding to an increase in pressure). Si-contents in higher-P phengites are scattered, reflecting subsequent muscovite growth. The Si trend is matched by a southward increase in the 40Ar/39Ar total gas ages of white micas. Phengite from the north are characterized by younger ages (~115 Ma) and flatter 40Ar/39Ar spectra. Farther south, phengites and paragonites yield older 40Ar/39Ar ages. These samples yield convex, staircase 40Ar/39Ar spectra that initiate ~115-120 Ma and flatten-out ~130-138 Ma. Modeling using MacArgon proposes that an initial cooling of HP/LT metamorphism occurred ~130-138 Ma, recorded in the high-Si phengites and paragonites. Following initial cooling, modeling suggests HP/LT rocks stalled in the greenschist facies field before subsequent exhumation, resulting in the staircase 40Ar/39Ar spectra. Flatter 40Ar/39Ar spectra recorded by the northern samples and modeling of 40Ar/39Ar results from the southern samples suggest that these rocks from metamorphic core of the BR were exhumed to temperatures < 300°C by ~115 Ma.

  15. 75 FR 66300 - Amendment of Class E Airspace; Searcy, AR

    Science.gov (United States)

    2010-10-28

    ...-1182; Airspace Docket No. 09-ASW-37] Amendment of Class E Airspace; Searcy, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Searcy, AR. Decommissioning of the Searcy non-directional beacon (NDB) at Searcy Municipal Airport, Searcy, AR, has made this...

  16. 75 FR 29654 - Amendment of Class E Airspace; Manila, AR

    Science.gov (United States)

    2010-05-27

    ...-1184; Airspace Docket No. 09-ASW-39] Amendment of Class E Airspace; Manila, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila Municipal Airport, Manila, AR has made this...

  17. Noninvasive Detection of AR-FL/AR-V7 as a Predictive Biomarker for Therapeutic Resistance in Men with Metastatic Castration-Resistant Prostate Cancer

    Science.gov (United States)

    2017-10-01

    acknowledged federal support) 5. Antonarakis ES, Armstrong AJ, Dehm SM, Luo J. Androgen receptor variant-driven prostate cancer : clinical implications...Resistant Prostate Cancer abstract Purpose A splice variant of the androgen receptor , AR-V7, confers resistance to AR-targeted therapies (ATTs) but not...androgen receptor ; AR-V7, androgen receptor splice variant 7; mCRPC, metastatic castration-resistant prostate cancer ; n/N, number of patients in that

  18. XRD-based 40Ar/39Ar age correction for fine-grained illite, with application to folded carbonates in the Monterrey Salient (northern Mexico)

    Science.gov (United States)

    Fitz-Díaz, Elisa; Hall, Chris M.; van der Pluijm, Ben A.

    2016-05-01

    Due to their minute size, 40Ar/39Ar analysis of illite faces significant analytical challenges, including mineral characterization and, especially, effects of grain size and crystallography on 39Ar recoil. Quantifying the effects of 39Ar recoil requires the use of sample vacuum encapsulation during irradiation, which permits the measurement of the fraction of recoiled 39Ar as well as the 39Ar and 40Ar∗ retained within illite crystals that are released during step heating. Total-Gas Ages (TGA) are calculated by using both recoiled and retained argon, which is functionally equivalent to K-Ar ages, while Retention Ages (RA) only involve retained Ar in the crystal. Natural applications have shown that TGA fits stratigraphic constraints of geological processes when the average illite crystallite thickness (ICT) is smaller than 10 nm, and that RA matches these constraints for ICTs larger than 50 nm. We propose a new age correction method that takes into account the average ICT and corresponding recoiled 39Ar for a sample, with X-ray Corrected Ages (XCA) lying between Total-Gas and Retention Ages depending on ICT. This correction is particularly useful in samples containing authigenic illite formed in the anchizone, with typical ICT values between 10 and 50 nm. In three samples containing authigenic illite from Cretaceous carbonates in the Monterrey Salient in northern Mexico, there is a range in TGAs among the different size-fractions of 46-49, 36-43 and 40-52 Ma, while RAs range from 54-64, 47-52 and 53-54 Ma, respectively. XCA calculations produce tighter age ranges for these samples of 52.5-56, 45.5-48.5 and 49-52.5 Ma, respectively. In an apparent age vs ICT or %2M 1illite plot, authigenic illite grains show a slope that is in general slightly positive for TGA, slightly negative for RA, but close to zero for XCA, with thinner crystallites showing more dispersion than thicker ones. In order to test if dispersion is due to a different formation history or the result

  19. residuos orgánicos

    Directory of Open Access Journals (Sweden)

    T. M. Hernández-Mendoza

    2007-01-01

    Full Text Available Los materiales orgánicos pueden constituir una alternativa eficaz al uso de fertilizantes sintéticos, siempre y cuando se tomen en cuenta de manera apropiada las diversas variables bióticas y abióticas que influyen sobre su descomposición en el suelo. Una forma de proceder es a través del empleo de diferentes indicadores que infieran su tasa de mineralización y capacidad de aporte nitrogenado (CAN. Entre estos, destaca el uso de la relación carbono:nitrógeno (C/N como índice de la susceptibilidad de los residuos orgánicos al ataque de la biomasa microbiana; sin embargo, su empleo ha generado resultados contradictorios, por lo que en el presente estudio se comparó la mineralización de residuos con diferente composición bioquímica para precisar un mejor indicador de la CAN. Para ello, se evaluó por incubación in vitro los residuos aplicados en suelo Regosol eútrico, a 30 oC y capacidad de campo constantes durante 20 semanas. La tendencia de la mineralización e inmovilización de N dependieron de la composición bioquímica del material, donde su relación C/N se asoció significativamente con la mineralización del N lábil del suelo, pero no así con la descomposición neta de los residuos. En contraste, la concentración de la lignina en el residuo tuvo una tendencia lineal con el N lábil potencialmente mineralizable y su tasa de mineralización, estimando de manera significativa la CAN.

  20. 40Ar-39Ar laser probe dating of individual clinopyroxene inclusions in Premier eclogitic diamonds

    International Nuclear Information System (INIS)

    Burgess, R.; Turner, G.; Laurenzi, M.; Harris, J.W.

    1989-01-01

    The ages of seven individual clinopyroxene inclusions in Premier diamonds of eclogitic association have been determined using the 40 Ar- 39 Ar dating technique. Syngenetic inclusions weighing between 10 and 130 μg were exposed on cleaved surfaces of the diamonds and analysed using a laser probe. The inclusion ages were found to be in the range 1111±35 to 1254±38 Ma with an average of 1185±94 Ma. The ages obtained are in good agreement with previous determinations made on aggregates of eclogitic inclusions from Premier diamonds and demonstrate the applicability of the laser probe to dating individual diamond inclusions. (orig.)

  1. Piesaistes stila saistība ar apmierinātību ar dzīvi

    OpenAIRE

    Čiekure, Līva

    2015-01-01

    Pētījuma mērķis ir noskaidrot vai pastāv saistības starp piesaistes stilu un apmierinātību ar dzīvi. Tika aptaujāti 100 respondenti- 50 sievietes un 50 vīrieši. Pētījumā tika izmantotas Piesaistes stilu aptauja (Attachment Styles -Inventory /ASI/, Sperling & Berman, 1991), Latvijā adaptējusi Baiba Martinsone (2003) un Apmierinātības ar dzīvi aptauja ( Satisfaction with life scales,/SWLS/, Diener, 1985), Latvijā adaptēja Maslovska, Voitkāne, Miezīte & Raščevska ( 2005) un Upmane (Upmane, 2010)...

  2. CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.

    Science.gov (United States)

    Ito, Saya; Ueno, Akihisa; Ueda, Takashi; Nakagawa, Hideo; Taniguchi, Hidefumi; Kayukawa, Naruhiro; Fujihara-Iwata, Atsuko; Hongo, Fumiya; Okihara, Koji; Ukimura, Osamu

    2018-04-03

    The androgen receptor (AR) is a ligand-dependent transcription factor that promotes prostate cancer (PC) cell growth through control of target gene expression. This report suggests that Canopy FGF signaling regulator 2 (CNPY2) controls AR protein levels in PC cells. We found that AR was ubiquitinated by an E3 ubiquitin ligase, myosin regulatory light chain interacting protein (MYLIP) and then degraded through the ubiquitin-proteasome pathway. CNPY2 decreased the ubiquitination activity of MYLIP by inhibition of interaction between MYLIP and UBE2D1, an E2 ubiquitin ligase. CNPY2 up-regulated gene expression of AR target genes such as KLK3 gene which encodes the prostate specific antigen (PSA) and promoted cell growth of PC cells. The cell growth inhibition by CNPY2 knockdown was rescued by AR overexpression. Furthermore, positive correlation of expression levels between CNPY2 and AR/AR target genes was observed in tissue samples from human prostate cancer patients. Together, these results suggested that CNPY2 promoted cell growth of PC cells by inhibition of AR protein degradation through MYLIP-mediated AR ubiquitination.

  3. 40Ar/39Ar dates in the Central Cordillera of Colombia: Evidence for an upper triassic regional tecnomagmatic event

    International Nuclear Information System (INIS)

    Vinasco, C.J.; Cordani, U.G.; Vasconcelos, P

    2001-01-01

    The Coastal, Western, Central and the Eastern Cordilleras constitute four independent mountain ranges in the Northern Andes. The Coastal and Western Cordillera comprises allochthonous oceanic sequences of basic volcanic rocks and marine sediments of Cenozoic and Upper Cretaceous age (Aspden et al., 1987). The so-called Central Cordillera Polymetamorphic Complex (Restrepo and Toussaint, 1982), made up the pre-Mesozoic Central Cordillera basement, consists of low through high-grade metamorphic rocks intruded by Meso-Cenozoic batholiths. The Eastern Cordillera is a polydeformed continental mountain range consisting of Precambrian and Paleozoic metamorphic and igneous rocks overlain by Paleozoic to Mesozoic sedimentary covers. The northern part of the Central Cordillera has been described as a suspect terrain affected by several tectonometamorphic episodes. The most important of them have been always considered those related to the Hercynian orogeny, in Devonian and Carboniferous times, and those occurring at the beginning of the Andean Cycle in the Cretaceous (Restrepo and Toussaint, 1982). A possible Lower Paleozoic and even Precambrian age for the basement of the terrain has also been proposed. Although some indications of a Permo-Triassic event are already available, this period was not considered as of great importance for the geologic evolution of the region. The available radiometric dates in the 200-250 Ma interval, for the Central Cordillera, are as follows: 1. One K-Ar whole rock age for a Granulite of 251±21 Ma. (Restrepo et al, 1991) of the El Retiro group SE of Medellin. However, a K-Ar biotite age of 110±10 Ma. (Toussaint et al., 1978) was obtained for a migmatite rock associated with the same group. 2. A Sm/Nd garnet and whole rock age of 226±17 Ma in rocks associated to granulites, SE of Medellin, interpreted as metamorphic ages (Correa and Martins, 2001). 3. K-Ar biotite dates for the Puqui metamorphic complex, occurring north of Medellin, ranging

  4. Oil Companies and Reserves | Compagnies et réserves pétrolières

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Top 20 World Oil CorporationsTop 20 des compagnies pétrolières mondialesSources: OPEC, Annual Statistical Bulletin, 2009; 2009 official reports of oil companies; British Petroleum, BP Statistical Review of Word Energy, 2010.Crude Oil Exports per Area (in Million Tonnes, 2009Exportations de pétrole brut par région (en millions de tonnes, 2009Sources : www.iea.org; www.opec.org; www.gecforum.org; British Petroleum, BP Statistical Review of World Energy, 2010.China’s Crude Oil Imports from Afr...

  5. A high-precision 40Ar/39Ar age for the Nördlinger Ries impact crater, Germany, and implications for the accurate dating of terrestrial impact events

    Science.gov (United States)

    Schmieder, Martin; Kennedy, Trudi; Jourdan, Fred; Buchner, Elmar; Reimold, Wolf Uwe

    2018-01-01

    40Ar/39Ar dating of specimens of moldavite, the formation of which is linked to the Ries impact in southern Germany, with a latest-generation ARGUS VI multi-collector mass spectrometer yielded three fully concordant plateau ages with a weighted mean age of 14.808 ± 0.021 Ma (± 0.038 Ma including all external uncertainties; 2σ; MSWD = 0.40, P = 0.67). This new best-estimate age for the Nördlinger Ries is in general agreement with previous 40Ar/39Ar results for moldavites, but constitutes a significantly improved precision with respect to the formation age of the distal Ries-produced tektites. Separates of impact glass from proximal Ries ejecta (suevite glass from three different surface outcrops) and partially melted feldspar particles from impact melt rock of the SUBO 18 Enkingen drill core failed to produce meaningful ages. These glasses show evidence for excess 40Ar introduction, which may have been incurred during interaction with hydrothermal fluids. Only partially reset 40Ar/39Ar ages could be determined for the feldspathic melt separates from the Enkingen core. The new 40Ar/39Ar results for the Ries impact structure constrain the duration of crater cooling, during the prevailing hydrothermal activity, to locally at least ∼60 kyr. With respect to the dating of terrestrial impact events, this paper briefly discusses a number of potential issues and effects that may be the cause for seemingly precise, but on a kyr-scale inaccurate, impact ages.

  6. Treating Asthma in Children Ages 12 and Older

    Science.gov (United States)

    ... Peak flow meter. American Academy of Allergy, Asthma & Immunology. https://www.aaaai.org/conditions-and-treatments/library/at-a-glance/peak-flow-meter. Accessed Sept. 8, 2016. Oct. 18, 2016 Original article: http://www.mayoclinic.org/diseases-conditions/childhood-asthma/ ...

  7. Proven Weight Loss Methods

    Science.gov (United States)

    Fact Sheet Proven Weight Loss Methods What can weight loss do for you? Losing weight can improve your health in a number of ways. It can lower ... at www.hormone.org/Spanish . Proven Weight Loss Methods Fact Sheet www.hormone.org

  8. Spina Bifida Clinic Directory

    Science.gov (United States)

    ... 7th Avenue S. Birmingham, AL 35233 (205) 939-5281 https://www.childrensal.org/SpinaBifidaProgram UAB Spain Rehab Adult ... Ave S Birmingham, AL 35249 Phone: (205) 934-4131 http://www.uabmedicine.org/locations/spain-rehabilitation-center Children’s ...

  9. 40Ar/ 39Ar and paleomagnetic results from Liberia and the Precambrian APW data base for the West African Shield

    Science.gov (United States)

    Onstott, T. C.; Dorbor, J.

    Lower amphibolite to granulite facies metamorphic rocks in Nimba County, Liberia have yielded 2.2-2.9 Ga RbSr whole rock ages, indicating that they are part of the Archean Liberian age province. We report a 2040 Ma 4040Ar/ 39Ar plateau date on hornblende from an amphibolite in this region, and suggest that these rocks were also severelyreworked during the Eburnean (˜2.0 Ga) metamorphic episode. 40Ar/ 39Ar analyses of biotite and feldspars from neighboring schists also indicate the presence of two mild thermal events, at 1.5 Ga and 0.6 Ga. Paleomagnetic analyses of samples from these same metamorphic rocks reveal three components of magnetization. The predominant and most stable component (273°E, 21°N) is considered to have been acquired as a result of pos Eburnean uplift and cooling at ˜ 2.0 Ga, whereas the two less stable components with poles at 235°E, 43°N and 16°E, 36°N, probably correlate with the 1.5 Ga and 0.6 Ga thermal pulses, respectively. Rock units from southern Liberia also yield two secondary magnetizations, one at 247°E, 37°N and the other at 104°E, 5°N, and a 1.5 Ga 40Ar/ 39Ar date on plagioclase. Comparison of the paleomagnetic poles corresponding to the ˜2.0 Ga Eburnean component with published paleomagnetic data for West Africa is not consistent with prior interpretations of the polar wander path for West Africa. Our paleomagnetic data, when compared to poles of comparable age from the Kalahari Shield, still suggest that some form of displacement has occurred between the Kalahari and West African Shields since 2.0 Ga.

  10. Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer.

    Science.gov (United States)

    Khurana, Namrata; Kim, Hogyoung; Chandra, Partha K; Talwar, Sudha; Sharma, Pankaj; Abdel-Mageed, Asim B; Sikka, Suresh C; Mondal, Debasis

    2017-11-01

    Prostate cancer (PCa) cells expressing full-length androgen receptor (AR-FL) are susceptible to androgen deprivation therapy (ADT). However, outgrowth of castration-resistant prostate cancer (CRPC) can occur due to the expression of constitutively active (ligand-independent) AR splice variants, particularly AR-V7. We previously demonstrated that sulforaphane (SFN), an isothiocyanate phytochemical, can decrease AR-FL levels in the PCa cell lines, LNCaP and C4-2B. Here, we examined the efficacy of SFN in targeting both AR-FL and AR-V7 in the CRPC cell line, CWR22Rv1 (22Rv1). MTT cell viability, wound-heal assay, and colony forming unit (CFU) measurements revealed that 22Rv1 cells are resistant to the anti-androgen, enzalutamide (ENZ). However, co-exposure to SFN sensitized these cells to the potent anticancer effects of ENZ (PAR-FL and AR-V7 levels, and immunofluorescence microscopy (IFM) depicted decreased AR in both cytoplasm and nucleus with SFN treatment. SFN increased both ubiquitination and proteasomal activity in 22Rv1 cells. Studies using a protein synthesis inhibitor (cycloheximide) or a proteasomal inhibitor (MG132) indicated that SFN increases both ubiquitin-mediated aggregation and subsequent proteasomal-degradation of AR proteins. Previous studies reported that SFN inhibits the chaperone activity of heat-shock protein 90 (Hsp90) and induces the nuclear factor erythroid-2-like 2 (Nrf2) transcription factor. Therefore, we investigated whether the Hsp90 inhibitor, ganetespib (G) or the Nrf2 activator, bardoxolone methyl (BM) can similarly suppress AR levels in 22Rv1 cells. Low doses of G and BM, alone or in combination, decreased both AR-FL and AR-V7 levels, and combined exposure to G+BM sensitized 22Rv1 cells to ENZ. Therefore, adjunct treatment with the phytochemical SFN or a safe pharmaceutical combination of G+BM may be effective against CRPC cells, especially those expressing AR-V7.

  11. Hybrid simulation of electron energy distributions and plasma characteristics in pulsed RF CCP sustained in Ar and SiH4/Ar discharges

    Science.gov (United States)

    Wang, Xi-Feng; Jia, Wen-Zhu; Song, Yuan-Hong; Zhang, Ying-Ying; Dai, Zhong-Ling; Wang, You-Nian

    2017-11-01

    Pulsed-discharge plasmas offer great advantages in deposition of silicon-based films due to the fact that they can suppress cluster agglomeration, moderate the energy of bombarding ions, and prolong the species' diffusion time on the substrate. In this work, a one-dimensional fluid/Monte-Carlo hybrid model is applied to study pulse modulated radio-frequency (RF) plasmas sustained in capacitively coupled Ar and SiH4/Ar discharges. First, the electron energy distributions in pulsed Ar and SiH4/Ar plasmas have been investigated and compared under identical discharge-circuit conditions. The electron energy distribution function (EEDF) in Ar discharge exhibits a familiar bi-Maxwellian shape during the power-on phase of the pulse, while a more complex (resembling a multi-Maxwellian) distribution with extra inflection points at lower energies is observed in the case of the SiH4/Ar mixture. These features become more prominent with the increasing fraction of SiH4 in the gas mixture. The difference in the shape of the EEDF (which is pronounced inside the plasma but not in the RF sheath where electron heating occurs) is mainly attributed to the electron-impact excitations of SiH4. During the power-off phase of the pulse, the EEDFs in both Ar and SiH4/Ar discharges evolve into bi-Maxwellian shapes, with shrinking high energy tails. Furthermore, the parameter of ion species in the case of SiH4/Ar discharge is strongly modulated by pulsing. For positive ions, such as SiH3+ and Si2H4+ , the particle fluxes overshoot at the beginning of the power-on interval. Meanwhile, for negative ions such as SiH2- and SiH3- , density profiles observed between the electrodes are saddle-shaped due to the repulsion by the self-bias electric field as it builds up. During the power-off phase, the wall fluxes of SiH2- and SiH3- gradually increase, leading to a significant decrease in the net surface charge density on the driven electrode. Compared with ions, the density of SiH3 is poorly modulated

  12. Dionisos y la orgía

    Directory of Open Access Journals (Sweden)

    ANTONIO ESCOHOTADO

    1986-01-01

    Full Text Available El artículo analiza las descripciones de las orgías rituales dionisiacas de la antigua Grecia en la literatura de la época (las tragedias de Eurípides y Sófocles, p.e. utilizando interpretaciones de la psicología moderna para el examen de dicha cultura. El papel del consumo de alcohol se compara con el de las drogas de nuestra sociedad actual.

  13. Paleomagnetism.org : An online multi-platform open source environment for paleomagnetic data analysis

    NARCIS (Netherlands)

    Koymans, Mathijs R.; Langereis, C.G.; Pastor-Galán, D.; van Hinsbergen, D.J.J.

    2016-01-01

    This contribution provides an overview of Paleomagnetism.org, an open-source, multi-platform online environment for paleomagnetic data analysis. Paleomagnetism.org provides an interactive environment where paleomagnetic data can be interpreted, evaluated, visualized, and exported. The

  14. 40Ar/(39)Ar geochronology and paleomagnetic stratigraphy of the Lukeino and lower Chemeron Formations at Tabarin and Kapcheberek, Tugen Hills, Kenya.

    Science.gov (United States)

    Deino, Alan L; Tauxe, Lisa; Monaghan, Marc; Hill, Andrew

    2002-01-01

    (40)Ar/(39)Ar single-crystal laser-fusion dating, K-Ar dating, and paleomagnetic reversal stratigraphy have been used to determine the chronostratigraphy of the Kabarnet Trachyte, Lukeino Formation, Kaparaina Basalt Formation, and Chemeron Formation at the sites of Kapcheberek (BPRP#77) and Tabarin (BPRP#77) in the Tugen Hills, Kenya. The succession ranges in age from 6.56-3.8 Ma. The upper Lukeino Formation at Kapcherberek, including the fauna from the site BPRP#76, was deposited during chron C3r and can be constrained to the interval 5.88-5.72 Ma. The Chemeron Formation at Tabarin includes at the base an ignimbrite and associated basal air-fall tuff with a combined age of 5.31+/-0.03 Ma. Sedimentary and volcaniclastic rocks of the Chemeron Formation which unconformably overlie the ignimbrite record chrons C3n.2n through C2Ar. The combined(40)Ar/(39)Ar and paleomagnetic data constrain the age of this sequence to 4.63-3.837 Ma. The age of the Tabarin mandible fragment (KNM-TH 13150) and associated fauna at site BPRP#77 in the Chemeron Formation is 4.48-4.41 Ma, marginally older than similar early hominids from Aramis, Ethiopia. Basin subsidence appears to be defining an overall accumulation rate of about 17 cm/ka over the 2.7 Ma represented at Tabarin and Kapcheberek, despite episodes of rapid accumulation and hiatuses. Copyright 2002 Academic Press.

  15. OpenOffice.org -toimisto-ohjelmiston soveltuvuus Sastamalan Tukipalvelu Oy:lle : selvitys

    OpenAIRE

    Ojanen, Olli-Veikko

    2009-01-01

    Tässä opinnäytetyössä selvitettiin OpenOffice.org toimisto-ohjelmiston soveltuvuutta Sastamalan Tukipalvelu Oy:lle, joka huolehtii osakkaittensa tieto-, talous- ja henkilöstöhallinnon palveluista. Sastamalan Tukipalvelu Oy:n osakkaina ovat Kiikoisten, Lavian ja Punkalaitumen kunnat, Sastamalan kaupunki, Sastamalan perusturvakuntayhtymä sekä Sastamalan koulutuskuntayhtymä. Selvityksen tavoitteena oli tuoda esille OpenOffice.org -toimisto-ohjelmistoon siirtymisen hyötyjä, joi...

  16. NEW ACCURATE MEASUREMENT OF {sup 36}ArH{sup +} AND {sup 38}ArH{sup +} RO-VIBRATIONAL TRANSITIONS BY HIGH RESOLUTION IR ABSORPTION SPECTROSCOPY

    Energy Technology Data Exchange (ETDEWEB)

    Cueto, M.; Herrero, V. J.; Tanarro, I.; Doménech, J. L. [Molecular Physics Department, Instituto de Estructura de la Materia (IEM-CSIC), Serrano 123, E-28006 Madrid (Spain); Cernicharo, J. [Department of Astrophysics, CAB. INTA-CSIC. Crta Torrejón-Ajalvir Km 4, E-28850 Torrejón de Ardoz, Madrid (Spain); Barlow, M. J.; Swinyard, B. M., E-mail: jl.domenech@csic.es [Department of Physics and Astronomy, University College London. Gower Street, London WC1E 6BT (United Kingdom)

    2014-03-01

    The protonated argon ion, {sup 36}ArH{sup +}, was recently identified in the Crab Nebula from Herschel spectra. Given the atmospheric opacity at the frequency of its J = 1-0 and J = 2-1 rotational transitions (617.5 and 1234.6 GHz, respectively), and the current lack of appropriate space observatories after the recent end of the Herschel mission, future studies on this molecule will rely on mid-infrared observations. We report on accurate wavenumber measurements of {sup 36}ArH{sup +} and {sup 38}ArH{sup +} rotation-vibration transitions in the v = 1-0 band in the range 4.1-3.7 μm (2450-2715 cm{sup –1}). The wavenumbers of the R(0) transitions of the v = 1-0 band are 2612.50135 ± 0.00033 and 2610.70177 ± 0.00042 cm{sup –1} (±3σ) for {sup 36}ArH{sup +} and {sup 38}ArH{sup +}, respectively. The calculated opacity for a gas thermalized at a temperature of 100 K and with a linewidth of 1 km s{sup –1} of the R(0) line is 1.6 × 10{sup –15} × N({sup 36}ArH{sup +}). For column densities of {sup 36}ArH{sup +} larger than 1 × 10{sup 13} cm{sup –2}, significant absorption by the R(0) line can be expected against bright mid-IR sources.

  17. A Framework for WWW Query Processing

    Science.gov (United States)

    Wu, Binghui Helen; Wharton, Stephen (Technical Monitor)

    2000-01-01

    Query processing is the most common operation in a DBMS. Sophisticated query processing has been mainly targeted at a single enterprise environment providing centralized control over data and metadata. Submitting queries by anonymous users on the web is different in such a way that load balancing or DBMS' accessing control becomes the key issue. This paper provides a solution by introducing a framework for WWW query processing. The success of this framework lies in the utilization of query optimization techniques and the ontological approach. This methodology has proved to be cost effective at the NASA Goddard Space Flight Center Distributed Active Archive Center (GDAAC).

  18. The Threat of Latin America Populism

    Science.gov (United States)

    2010-04-07

    Minister), August 14,2008, httpJ/www.cavallo.corn.ar/?p=173 , (accessed December 29, 2009). 38 1NV AP, " Tecnologia de Avanzada a Medida, Argentina.ar...December 5, 2008, http ://www.argentina.ar/ es/ciencia-y-educacion/C343 -invap- tecnologia -de-avanzada -a- medida.php (accessed December 15, 2009...ch_vez_obliga_a_)a_tv_por_cable_a_sumarse_a_)a_cade na nacion/ INV AP, " Tecnologia de Avanzada a Medida, Argentina.ar, December 5, 2008, http

  19. Beam-induced back-streaming electron suppression analysis for an accelerator type neutron generator designed for 40Ar/39Ar geochronology.

    Science.gov (United States)

    Waltz, Cory; Ayllon, Mauricio; Becker, Tim; Bernstein, Lee; Leung, Ka-Ngo; Kirsch, Leo; Renne, Paul; Bibber, Karl Van

    2017-07-01

    A facility based on a next-generation, high-flux D-D neutron generator has been commissioned and it is now operational at the University of California, Berkeley. The current generator designed for 40 Ar/ 39 Ar dating of geological materials produces nearly monoenergetic 2.45MeV neutrons at outputs of 10 8 n/s. The narrow energy range is advantageous relative to the 235 U fission spectrum neutrons due to (i) reduced 39 Ar recoil energy, (ii) minimized production of interfering argon isotopes from K, Ca, and Cl, and (iii) reduced total activity for radiological safety and waste generation. Calculations provided show that future conditioning at higher currents and voltages will allow for a neutron output of over 10 10 n/s, which is a necessary requirement for production of measurable quantities of 39 Ar through the reaction 39 K(n,p) 39 Ar. A significant problem encountered with increasing deuteron current was beam-induced electron backstreaming. Two methods of suppressing secondary electrons resulting from the deuterium beam striking the target were tested: the application of static electric and magnetic fields. Computational simulations of both techniques were done using a finite element analysis in COMSOL Multiphysics ® . Experimental tests verified these simulations. The most reliable suppression was achieved via the implementation of an electrostatic shroud with a voltage offset of -800V relative to the target. Copyright © 2017. Published by Elsevier Ltd.

  20. Advisory Committee on Immunization Practices Recommended Immunization Schedule for Adults Aged 19 Years or Older - United States, 2018.

    Science.gov (United States)

    Kim, David K; Riley, Laura E; Hunter, Paul

    2018-02-09

    In October 2017, the Advisory Committee on Immunization Practices (ACIP) voted to approve the Recommended Immunization Schedule for Adults Aged 19 Years or Older, United States, 2018. The 2018 adult immunization schedule summarizes ACIP recommendations in two figures and a table of contraindications and precautions for vaccines recommended for adults, and is intended is to assist health care providers in implementing the current ACIP recommendations for vaccinating adults. The schedule can be found at https://www.cdc.gov/vaccines/schedules.* The full ACIP recommendations for each vaccine are available at https://www.cdc.gov/vaccines/hcp/acip-recs/index.html. The 2018 adult immunization schedule has also been approved by the American College of Physicians (https://www.acponline.org), the American Academy of Family Physicians (https://www.aafp.org), the American College of Obstetricians and Gynecologists (https://www.acog.org), and the American College of Nurse-Midwives (http://www.midwife.org). The ACIP-recommended use of each vaccine is developed after an in-depth review of vaccine-related data, including data on disease epidemiology, vaccine efficacy and effectiveness, vaccine safety, feasibility of program implementation, and economic aspects of immunization policy (1).

  1. Chewing lice of the genus Myrsidea Waterston (Phthiraptera: Menoponidae) from the Emberizidae and Thraupidae (Passeriformes) in Mato Grosso do Sul, Brazil

    Czech Academy of Sciences Publication Activity Database

    Sychra, O.; Literák, I.; Čapek, Miroslav

    2009-01-01

    Roč. 38, č. 4 (2009), s. 501-503 ISSN 1519-566X R&D Projects: GA AV ČR IAA601690901 Institutional research plan: CEZ:AV0Z60930519 Keywords : Bunting * tanager Subject RIV: EG - Zoology Impact factor: 0.586, year: 2009 http://www.scielo.br/pdf/ne/v38n4/v38n4a10.pdf

  2. Special Section: Preventing, Detecting, and Treating Colorectal Cancer

    Science.gov (United States)

    ... a week-long series to promote colon and rectal (colorectal) cancer awareness and screening. Following that, research showed that ... niddk.nih.gov The American Cancer Society: www.cancer.org The American Society of Colon & Rectal Surgeons: www.fascrs.org Spring 2009 Issue: Volume ...

  3. Measurements of the {sup 40}Ar(n, γ){sup 41}Ar radiative-capture cross section between 0.4 and 14.8 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Bhike, Megha, E-mail: megha@tunl.duke.edu [Department of Physics, Duke University, Durham, NC 27708 (United States); Triangle Universities Nuclear Laboratory, Durham, NC 27708 (United States); Fallin, B.; Tornow, W. [Department of Physics, Duke University, Durham, NC 27708 (United States); Triangle Universities Nuclear Laboratory, Durham, NC 27708 (United States)

    2014-09-07

    The {sup 40}Ar(n, γ){sup 41}Ar neutron capture cross section has been measured between 0.4 and 14.8 MeV neutron energy using the activation technique. The data are important for estimating backgrounds in argon-based neutrino and dark-matter detectors and in the neutrino-less double-beta decay search GERDA, which uses liquid argon as cooling and shielding medium. For the first time the {sup 40}Ar(n, γ){sup 41}Ar cross section has been measured for neutron energies above 1 MeV. Our results are compared to the evaluation ENDF/B-VII.1 and the calculated prediction TENDL-2013. The latter agrees very well with the present results.

  4. WorldWideScience.org: the global science gateway.

    Science.gov (United States)

    Fitzpatrick, Roberta Bronson

    2009-10-01

    WorldWideScience.org is a Web-based global gateway connecting users to both national and international scientific databases and portals. This column will provide background information on the resource as well as introduce basic searching practices for users.

  5. 75 FR 53876 - Proposed Establishment of Class E Airspace; Berryville, AR

    Science.gov (United States)

    2010-09-02

    ... Class E Airspace; Berryville, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to establish Class E airspace at Berryville, AR... SIAPs operations at Carroll County Airport, Berryville, AR. Controlled airspace is needed for the safety...

  6. 78 FR 25231 - Proposed Establishment of Class E Airspace; Colt, AR

    Science.gov (United States)

    2013-04-30

    ...-1281; Airspace Docket No. 12-ASW-13] Proposed Establishment of Class E Airspace; Colt, AR AGENCY... action proposes to establish Class E airspace at Colt, AR. Controlled airspace is necessary to...-mile radius of Delta Regional Airport, Colt, AR, to accommodate new standard instrument approach...

  7. Spent fuel isotopic composition data base system on WWW. SFCOMPO on W3

    International Nuclear Information System (INIS)

    Suyama, Kenya

    1997-11-01

    Spent Fuel Composition Data Base System 'SFCOMPO' has been developed on IBM compatible PC. This data base system is not widely used, since users must purchase the data base software by themselves. 'SFCOMPO on W3' is a system to overcome this problem. User can search and visualize the data in the data base by accessing WWW server through the Internet from local machine. Only a browsing software to access WWW should be prepared. It enables us to easily search data of spent fuel composition if we can access the Internet. This system can be operated on WWW server machine which supports use of Common Gateway Interface (CGI). This report describes the background of the development of SFCOMPO on W3 and is it's user's manual. (author)

  8. Cerebral A1 adenosine receptors (A1AR) in liver cirrhosis

    International Nuclear Information System (INIS)

    Boy, Christian; Meyer, Philipp T.; Kircheis, Gerald; Haussinger, Dieter; Holschbach, Marcus H.; Coenen, Heinz H.; Herzog, Hans; Elmenhorst, David; Kaiser, Hans J.; Zilles, Karl; Bauer, Andreas

    2008-01-01

    The cerebral mechanisms underlying hepatic encephalopathy (HE) are poorly understood. Adenosine, a neuromodulator that pre- and postsynaptically modulates neuronal excitability and release of classical neurotransmitters via A 1 adenosine receptors (A 1 AR), is likely to be involved. The present study investigates changes of cerebral A 1 AR binding in cirrhotic patients by means of positron emission tomography (PET) and [ 18 F]CPFPX, a novel selective A 1 AR antagonist. PET was performed in cirrhotic patients (n = 10) and healthy volunteers (n = 10). Quantification of in vivo receptor density was done by Logan's non-invasive graphical analysis (pons as reference region). The outcome parameter was the apparent binding potential (aBP, proportional to B max /K D ). Cortical and subcortical regions showed lower A 1 AR binding in cirrhotic patients than in controls. The aBP changes reached statistical significance vs healthy controls (p 1 AR binding may further aggravate neurotransmitter imbalance at the synaptic cleft in cirrhosis and hepatic encephalopathy. Different pathomechanisms may account for these alterations including decrease of A 1 AR density or affinity, as well as blockade of the A 1 AR by endogenous adenosine or exogenous xanthines. (orig.)

  9. Decisive factors affecting plasma resistance and roughness formation in ArF photoresist

    Energy Technology Data Exchange (ETDEWEB)

    Jinnai, Butsurin; Uesugi, Takuji; Koyama, Koji; Samukawa, Seiji [Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Kato, Keisuke; Yasuda, Atsushi; Maeda, Shinichi [Yokohama Research Laboratories, Mitsubishi Rayon Co., Ltd, 10-1 Daikoku-cho, Tsurumi-ku, Yokohama 230-0053 (Japan); Momose, Hikaru, E-mail: samukawa@ifs.tohoku.ac.j [Corporate Research Laboratories, Mitsubishi Rayon Co., Ltd, 2-1 Miyuki-cho, Otake, Hiroshima 739-0693 (Japan)

    2010-10-06

    Low plasma resistance and roughness formation in an ArF photoresist are serious issues in plasma processes. To resolve these issues, we investigated several factors that affect the roughness formation and plasma resistance in an ArF photoresist. We used our neutral beam process to categorize the effects of species from the plasma on the ArF photoresist into physical bombardment, chemical reactions and ultraviolet/vacuum ultraviolet (UV/VUV) radiation. The UV/VUV radiation drastically increased the etching rates of the ArF photoresist films, and, in contrast, chemical reactions increased the formation of surface roughness. FTIR analysis indicated that the UV/VUV radiation preferentially dissociates C-H bonds in the ArF photoresist, rather than C=O bonds, because of the dissociation energies of the bonds. This indicated that the etching rates of the ArF photoresist are determined by the UV/VUV radiation because this radiation can break C-H bonds, which account for the majority of structures in the ArF photoresist. In contrast, FTIR analysis showed that chemical species such as radicals and ions were likely to react with C=O bonds, in particular C=O bonds in the lactone groups of the ArF photoresist, due to the structural and electronic effects of the lactone groups. As a result, the etching rates of the ArF photoresist can vary in different bond structures, leading to increased surface roughness in the ArF photoresist.

  10. Searches for the Standard Model Higgs boson at the Tevatron collider

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Wade C. [Michigan State Univ., East Lansing, MI (United States). Dept. of Physics and Astronomy; Junk, Thomas R. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-01-01

    During Run II of the Tevatron collider, which took place from 2001 until 2011, the CDF and D0 detectors each collected approximately 10 fb -1 of www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oasis="http://docs.oasis-open.org/ns/oasis-exchange/table"> collision data at a center-of-mass energy of www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oasis="http://docs.oasis-open.org/ns/oasis-exchange/table">. This dataset allowed for tests for the presence of the SM Higgs boson in the mass range 90-200 GeV in the production modes gg → H, W/ZH, vector-boson fusion, and www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oasis="http://docs.oasis-open.org/ns/oasis-exchange/table">H, with H decay modes H → www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oasis="http://docs.oasis-open.org/ns/oasis-exchange/table">, H → W+W-, H →

  11. 77 FR 42430 - Establishment of Class E Airspace; West Memphis, AR

    Science.gov (United States)

    2012-07-19

    ...-0155; Airspace Docket No. 12-ASW-1] Establishment of Class E Airspace; West Memphis, AR AGENCY: Federal... at West Memphis, AR. Separation of existing Class E airspace surrounding West Memphis Municipal... the West Memphis, AR, area, creating controlled airspace at West Memphis Municipal Airport (77 FR...

  12. 76 FR 53359 - Proposed Establishment of Class E Airspace; Nashville, AR

    Science.gov (United States)

    2011-08-26

    ...-0497; Airspace Docket No. 11-ASW-4] Proposed Establishment of Class E Airspace; Nashville, AR AGENCY... action proposes to establish Class E airspace at Nashville, AR. Controlled airspace is necessary to... approach procedures at Howard County Airport, Nashville, AR. Controlled airspace is needed for the safety...

  13. 75 FR 5904 - Proposed Amendment of Class E Airspace; Magnolia, AR

    Science.gov (United States)

    2010-02-05

    ...-1179; Airspace Docket No. 09-ASW-35] Proposed Amendment of Class E Airspace; Magnolia, AR AGENCY... action proposes to amend Class E airspace at Magnolia, AR. Decommissioning of the Magnolia non-directional beacon (NDB) at Magnolia Municipal Airport, Magnolia, AR, has made this action necessary for the...

  14. Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.

    Science.gov (United States)

    Hsu, Cheng-Lung; Liu, Jai-Shin; Wu, Po-Long; Guan, Hong-Hsiang; Chen, Yuh-Ling; Lin, An-Chi; Ting, Huei-Ju; Pang, See-Tong; Yeh, Shauh-Der; Ma, Wen-Lung; Chen, Chung-Jung; Wu, Wen-Guey; Chang, Chawnshang

    2014-12-01

    Treatment with individual anti-androgens is associated with the development of hot-spot mutations in the androgen receptor (AR). Here, we found that anti-androgens-mt-ARs have similar binary structure to the 5α-dihydrotestosterone-wt-AR. Phage display revealed that these ARs bound to similar peptides, including BUD31, containing an Fxx(F/H/L/W/Y)Y motif cluster with Tyr in the +5 position. Structural analyses of the AR-LBD-BUD31 complex revealed formation of an extra hydrogen bond between the Tyr+5 residue of the peptide and the AR. Functional studies showed that BUD31-related peptides suppressed AR transactivation, interrupted AR N-C interaction, and suppressed AR-mediated cell growth. Combination of peptide screening and X-ray structure analysis may serve as a new strategy for developing anti-ARs that simultaneously suppress both wt and mutated AR function. Copyright © 2014 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  15. The SciELO Brazilian Scientific Journal Gateway and Open Archives; Usability of Hypermedia Educational e-Books; Building Upon the MyLibrary Concept To Better Meet the Information Needs of College Students; Open Archives and UK Institutions; The Utah Digital Newspapers Project; Examples of Practical Digital Libraries.

    Science.gov (United States)

    Marcondes, Carlos Henrique; Sayao, Luis Fernando; Diaz, Paloma; Gibbons, Susan; Pinfield, Stephen; Kenning, Arlitsch; Edge, Karen; Yapp, L.; Witten, Ian H.

    2003-01-01

    Includes six articles that focus on practical uses of technologies developed from digital library research in the areas of education and scholarship reflecting the international impact of digital library research initiatives. Includes the Scientific Electronic Library Online (SciELO) (Brazil); the National Science Foundation (NSF) (US); the Joint…

  16. The transcriptional programme of the androgen receptor (AR) in prostate cancer.

    Science.gov (United States)

    Lamb, Alastair D; Massie, Charlie E; Neal, David E

    2014-03-01

    The androgen receptor (AR) is essential for normal prostate and prostate cancer cell growth. AR transcriptional activity is almost always maintained even in hormone relapsed prostate cancer (HRPC) in the absence of normal levels of circulating testosterone. Current molecular techniques, such as chromatin-immunoprecipitation sequencing (ChIP-seq), have permitted identification of direct AR-binding sites in cell lines and human tissue with a distinct coordinate network evident in HRPC. The effectiveness of novel agents, such as abiraterone acetate (suppresses adrenal androgens) or enzalutamide (MDV3100, potent AR antagonist), in treating advanced prostate cancer underlines the on-going critical role of the AR throughout all stages of the disease. Persistent AR activity in advanced disease regulates cell cycle activity, steroid biosynthesis and anabolic metabolism in conjunction with regulatory co-factors, such as the E2F family, c-Myc and signal transducer and activator of transcription (STAT) transcription factors. Further treatment approaches must target these other factors. © 2013 The Authors. BJU International © 2013 BJU International.

  17. AR(p) -based detrended fluctuation analysis

    Science.gov (United States)

    Alvarez-Ramirez, J.; Rodriguez, E.

    2018-07-01

    Autoregressive models are commonly used for modeling time-series from nature, economics and finance. This work explored simple autoregressive AR(p) models to remove long-term trends in detrended fluctuation analysis (DFA). Crude oil prices and bitcoin exchange rate were considered, with the former corresponding to a mature market and the latter to an emergent market. Results showed that AR(p) -based DFA performs similar to traditional DFA. However, the former DFA provides information on stability of long-term trends, which is valuable for understanding and quantifying the dynamics of complex time series from financial systems.

  18. Pre-Himalayan tectono-magmatic imprints in the Darjeeling-Sikkim Himalaya (DSH) constrained by 40Ar/39Ar dating of muscovite

    Science.gov (United States)

    Acharyya, Subhrangsu K.; Ghosh, Subhajit; Mandal, Nibir; Bose, Santanu; Pande, Kanchan

    2017-09-01

    The Lower Lesser Himalayan Sequence (L-LHS) in Darjeeling-Sikkim Himalaya (DSH) displays intensely deformed, low-grade meta-sedimentary rocks, frequently intervened by granite intrusives of varied scales. The principal motivation of our present study is to constrain the timing of this granitic event. Using 40Ar/39Ar geochronology, we dated muscovite from pegmatites emplaced along the earliest fabric in the low grade Daling phyllite, and obtained ∼1850 Ma Ar-Ar muscovite cooling age, which is broadly coeval with crystallization ages of Lingtse granite protolith (e.g., 1800-1850 Ma U-Pb zircon ages) reported from the L-LHS. We present here field observations to show the imprints (tectonic fabrics) of multiple ductile deformation episodes in the LHS terrain. The earliest penetrative fabric, axial planar to N-S trending reclined folds, suggest a regional tectonic event in the DSH prior to the active phase of Indo-Asia collision. Based on the age of granitic bodies and their structural correlation with the earliest fabric, we propose that the L-LHS as a distinct convergent tectono-magmatic belt, delineating the northern margin of Indian craton in the framework of the ∼1850 Ma Columbia supercontinent assembly.

  19. A Study on Tracking and Augmentation in Mobile AR for e-Leisure

    Directory of Open Access Journals (Sweden)

    Seong-Wook Jang

    2018-01-01

    Full Text Available Recently, a mobile augmented reality (AR system with AR technology that requires high performance has become popular due to the improved performance of smartphones. In particular, mobile AR that directly interacts with outdoor environments has been in development because of increasing interest in e-leisure due to improvements in living standards. Therefore, this paper aims to study tracking and augmentation in mobile AR for e-leisure. We analyzed the performance of human body tracking application implemented in a mobile system (smartphone using three methods (marker-based, markerless, and sensor-based for the feasibility examination of human body tracking in mobile AR. Furthermore, game information augmentation was examined through the implementation of mobile AR using two methods (marker- and sensor-based.

  20. 75 FR 29656 - Amendment of Class E Airspace; Mountain View, AR

    Science.gov (United States)

    2010-05-27

    ...-1181; Airspace Docket No. 09-ASW-36] Amendment of Class E Airspace; Mountain View, AR AGENCY: Federal... Mountain View, AR. Decommissioning of the Wilcox non-directional beacon (NDB) at Mountain View Wilcox Memorial Field Airport, Mountain View, AR, has made this action necessary to enhance the safety and...

  1. 75 FR 6594 - Proposed Amendment of Class E Airspace; Osceola, AR

    Science.gov (United States)

    2010-02-10

    ...-1183; Airspace Docket No. 09-ASW-38] Proposed Amendment of Class E Airspace; Osceola, AR AGENCY... action proposes to amend Class E airspace at Osceola, AR. Decommissioning of the Osceola non-directional beacon (NDB) at Osceola Municipal Airport, Osceola, AR, has made this action necessary for the safety and...

  2. Caracterización de los desechos orgánicos del camal de Guayaquil

    OpenAIRE

    Arellano Arroba, Camilo David; Calle Cañizares, Jaime Alfredo

    2014-01-01

    El presente trabajo de investigación denominado Caracterización de los desechos orgánicos del camal de Guayaquil, es un proyecto que la Universidad de las Fuerzas Armadas ESPE ha emprendido con la finalidad de determinar la utilidad que se pueda darsela a los desechos orgánicos en los camales de las diferentes ciudades del país. La tecnología empleada para determinar las características energéticas de los desechos orgánicos del camal, consistió en el proceso bien conocido de la digestión anae...

  3. El Comercio Internacional de Productos Orgánicos: Retos y Desafíos

    OpenAIRE

    Evangelina Méndez

    2015-01-01

    Durante las actividades del proyecto de investigación Guía para exportar abono orgánico hacia los principales mercados de Estados Unidos, Europa y Sudamérica, el uso de una plataforma virtual permitió conocer e identificar el impacto de la tecnología en la producción y comercialización de productos orgánicos, que a su vez involucró: el interés por parte de productores orgánicos para darse a conocer a través de medios virtuales, el acceso a equipos que permiten controlar a tiempo eventuales pl...

  4. Alpine orogenic evolution from subduction to collisional thermal overprint: The 40Ar/39Ar age constraints from the Valaisan Ocean, central Alps

    DEFF Research Database (Denmark)

    Wiederkehr, Michael; Sudo, Masafumi; Bousquet, Romain

    2009-01-01

    in general. The timing of high-pressure metamorphism, subsequent retrogression and following Barrow-type overprint was studied by 40Ar/39Ar dating of biotite and several white mica generations that are well characterized in terms of mineral chemistry, texture and associated mineral assemblages. Four distinct...

  5. Percepção do Consumidor sobre Produtos Orgânicos

    Directory of Open Access Journals (Sweden)

    Dario de Oliveira Lima-Filho

    2012-05-01

    Full Text Available O objetivo deste estudo é analisar a percepção dos consumidores sobre produtos orgânicos, bem como a influência dos fatores sócio-demográficos e da frequência de consumo. Para tanto, foi feito um estudo quantitativo-descritivo junto a uma amostra probabilística de 400 pessoas, responsáveis pela compra de alimentos de sua família, durante junho de 2010, em Campo Grande-MS. Os entrevistados acreditam que os produtos orgânicos são mais saborosos, mais seguros quanto à saúde e higiene e têm melhor aparência do que os produtos convencionais. Além disso, verificou-se uma relação positiva entre a avaliação dos orgânicos e escolaridade, renda e frequência de consumo. DOI: 10.5585/remark.v11i1.2297

  6. Ramon Llull's Ars Magna

    DEFF Research Database (Denmark)

    Jensen, Thessa

    2018-01-01

    The Ars Magna of Ramon Llull must be seen as one of the first attempts to formalise language, thought processes, and creating a basis for rational discussions. It consists of so-called principles, concepts, which are defined and combined through the use of four main figures. Llull's contribution...

  7. ARS-Media for Excel

    Science.gov (United States)

    ARS-Media for Excel is an ion solution calculator that uses Microsoft Excel to generate recipes of salts for complex ion mixtures specified by the user. Generating salt combinations (recipes) that result in pre-specified target ion values is a linear programming problem. Thus, the recipes are genera...

  8. Investigation of the energy levels of 38AR

    International Nuclear Information System (INIS)

    Waanders, F.B.

    1975-07-01

    In this project information on the energy levels of 38 Ar was obtained by means of the (p,γ) reaction. The 1,1 MeV Cockroft-Walton accelerator of the Potchefstroom University for CHE was used to produce the proton beam while a 80 cm 3 Ge(Li) detector was used to detect the gamma-rays. Precise gamma-branchings were determined for 50 bound levels, of which four have not previously been determined. These branchings were obtained from the 28 resonances studied in the 37 Cl(p,γ) 38 Ar reaction. The resonance with a proton energy of (592 plus minus 3) keV was not detected previously. The resonance energies, Q-value and energies of the bound levels used in this project were taken from the study done by Alderliesten. The mean lifetimes of a few bound levels of 38 Ar were measured by means of the doppler shift attenuation method. The results concerning the bound states and mean lifetimes are in good agreement with previous experiments. Limitations on the spin and parities of 19 (p,γ) resonances have been set by means of Weisskopf estimates. Only those cases for which the spin could be limited to two values are discussed in the text. A summary of experimental data obtained on 38 Ar is compared with the results from shellmodel calculations done by various workers. A short discussion on the analogue states in 38 Ar is also given [af

  9. Reappraisal of Los Humeros Volcanic Complex by New U/Th Zircon and 40Ar/39Ar Dating: Implications for Greater Geothermal Potential

    Science.gov (United States)

    Carrasco-Núñez, G.; Bernal, J. P.; Dávila, P.; Jicha, B.; Giordano, G.; Hernández, J.

    2018-01-01

    Longevity and size of magmatic systems are fundamental factors for assessing the potential of a geothermal field. At Los Humeros volcanic complex (LHVC), the first caldera-forming event was reported at 460 ± 40 ka. New zircon U/Th and plagioclase 40Ar/39Ar dates of pre-, syn- and postcaldera volcanics allow a reappraisal of the evolution of the geothermally active LHVC. The age of the voluminous Xaltipan ignimbrite (115 km3 dense rock equivalent [DRE]) associated with the formation of the Los Humeros caldera is now constrained by two geochronometers (zircon U/Th and plagioclase 40Ar/39Ar dating) to 164 ± 4.2 ka, which postdates a long episode of precaldera volcanism (rhyolitic domes), the oldest age of which is 693.0 ± 1.9 ka (40Ar/39Ar). The inferred short residence time (around 5 ka) for the paroxysmal Xaltipan ignimbrite is indicative of rapid assembly of a large magma body and rejuvenation of the system due to recurrent recharge magmas, as it has been occurred in some other large magmatic systems. Younger ages than previously believed have been obtained also for the other voluminous explosive phases of the Faby fall tuff at ˜70 ka and the second caldera-forming Zaragoza ignimbrite with 15 km3 DRE, which erupted immediately after. Thus, the time interval that separates the two caldera-forming episodes at Los Humeros is only 94 kyr, which is a much shorter interval than suggested by previous K-Ar dates (410 kyr). This temporal proximity allows us to propose a caldera stage encompassing the Xaltipan and the Zaragoza ignimbrites, followed by emplacement at 44.8 ± 1.7 ka of rhyolitic magmas interpreted to represent a postcaldera, resurgent stage. Rhyolitic eruptions have also occurred during the Holocene (˜1,200 km3) and these new ages indicating much younger caldera-forming volcanism than previously believed are fundamental factors in the application of classical conductive models of heat resource, enhancing the heat production capacity and favor a higher

  10. 41Ar-concentration measurements at the Finnish TRIGA Mark II

    International Nuclear Information System (INIS)

    Tamminen, A.

    1970-01-01

    41 Ar-concentrations in the reactor hall and in the Ar-ventilation duct of FiR-1 (IRIGA Mark II, 250 kW) have been measured during normal operation conditions. Additional measurements have been performed varying Ar-ventilation and hall ventilation flow. A γ- and background compensated thin window proportional detector and a β-Geiger detector for 41 Ar-measurements are described. The hall concentration has also been estimated from background measurements with an unshielded Ge(Li)-detector. The saturation concentration in the reactor hall with and without the hall ventilation is about 1 x 10 -7 μCi/cm 3 and 3 x 10 -7 μCi/cm 3 , respectively. (author)

  11. 40Ar/ 39Ar dating of Late Permian evaporites, southeastern New Mexico, USA

    Science.gov (United States)

    Renne, Paul R.; Sharp, Warren D.; Montañez, Isabel P.; Becker, Tim A.; Zierenberg, Robert A.

    2001-12-01

    40Ar/ 39Ar dating of the potassium-magnesium sulfate mineral langbeinite from Permian evaporites of the Salado formation near Carlsbad, New Mexico, provides quantitative evidence that some salts in these deposits have not recrystallized for 251 Myr since deposition. Survival of Permian salts supports the possibility that Bacillus bacteria recovered from nearby halite was isolated in a closed system and represents a sample of uncontaminated Permian life. Local recrystallization of langbeinite and other nearby minerals is also indicated by the dating, suggesting both the need and the opportunity to document closed system behavior more rigorously. The shoaling and desiccation event recorded by the Salado formation began at least 1 Myr before the Permian-Triassic boundary. Temporal correlation of the Salado with the Zechstein evaporites of north-central Europe supports previously inferred regression models for the origin of these deposits. Significant paleoenvironmental change at the Permian-Triassic boundary thus occurred on a time scale more protracted than that implied by geologically instantaneous events such as bolide impacts.

  12. 75 FR 43884 - Proposed Amendment of Class E Airspace; Searcy, AR

    Science.gov (United States)

    2010-07-27

    ...-1182; Airspace Docket No. 09-ASW-37] Proposed Amendment of Class E Airspace; Searcy, AR AGENCY: Federal... proposes to amend Class E airspace at Searcy, AR. Decommissioning of the Searcy non-directional beacon (NDB) at Searcy Municipal Airport, Searcy, AR, has made this action necessary for the safety and management...

  13. Geochronological 40Ar/39Ar data on the submarine fault-scarps in the Sardinia channel (western mediterranean)

    International Nuclear Information System (INIS)

    Bouillin, J.P.; Tricart, P.; Mascle, G.; Monie, P.; Rolfo, F.; Torelli, L.

    1999-01-01

    Granite and gneiss have been sampled on the submarine fault scarps of the Sardinia Channel and have been dated using the 40 Ar/ 39 Ar method. The majority of rocks partially preserve Hercynian ages. Some of them display Lower Cretaceous ages. In addition, Upper Eocene-Oligocene argon resetting is recorded only in rocks from the southeast sector of the Channel. We thus propose that the basement of the Sardinia Channel occupied a shallow position within the stack of the Alpine tectonic units, behind the more deformed front of the internal zones of the Maghrebide Chain. (authors)

  14. Development of a search system of NRDF on WWW

    International Nuclear Information System (INIS)

    Masui, Hiroshi; Ohbayashi, Yoshihide; Aoyama, Shigeyoshi; Ohnishi, Akira; Kato, Kiyoshi; Chiba, Masaki

    2000-01-01

    We develop a data search system and a data entry system for the Nuclear Reaction Data File (NRDF), which is one of the charged-particle reaction database compiled by Japan Charged Particle Reaction Group (JCPRG). Using a WWW browser, we can easily search, retrieve and utilize the data of NRDF. (author)

  15. Estudio de separación de fases en sistemas líquido-líquido usando LIX 984N en fase orgánica

    Directory of Open Access Journals (Sweden)

    Castillo-Segura, J.

    2012-04-01

    Full Text Available In this work we studied the sedimentation and coalescence phenomena in liquid-liquid dispersion without chemical reaction, the aqueous electrolyte consisted of 0.25 M sodium sulfate and an organic phase characteristic organic extractant for copper (LIX 984N diluted in a commercial solvent (Shellsol 24 AR. The phenomena that dominate the phase separation have been studied by several researchers, which proposed a number of models to predict sedimentation and coalescence profiles. In this work we applied a semi-empirical model to describe the phenomena involved, varying the following experimental conditions: percentage of extractant in organic phase (5 - 30 % v / v, continuous phase (aqueous and organic, time and stirring speed (30 - 1800 s and 400 - 1200 rpm respectively. The main results show that from the 800 rpm of agitation this variable has no influence on primary breakup time, in the same way for 180 seconds of stirring produces the same effect. The fraction of dispersed phase in the packing zone found was 0.74. For higher levels of percentage of extractant in organic phase increased the phase separation time as when the organic phase was used as the continuous phase relative to the aqueous phase. We found a partial adjustment of the experimental data in relation to the simulated values , which is attributable to two factors: the initial inertia of the system once the agitation stopped and the existence of different times of inflection points of the curves of sedimentation and coalescence. In the different articles found in literature assume that the above phenomena occur simultaneously.

    En este trabajo se estudiaron los fenómenos de sedimentación y coalescencia en una dispersión líquido-líquido sin reacción química, la fase acuosa consistió en electrolito de sulfato de sodio 0,25 M y una fase orgánica de extractante característico para el cobre (LIX 984N diluido en un solvente comercial (shellsol 24 AR. Los fenómenos que

  16. Spent fuel isotopic composition data base system on WWW. SFCOMPO on W3

    Energy Technology Data Exchange (ETDEWEB)

    Suyama, Kenya [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-11-01

    Spent Fuel Composition Data Base System `SFCOMPO` has been developed on IBM compatible PC. This data base system is not widely used, since users must purchase the data base software by themselves. `SFCOMPO on W3` is a system to overcome this problem. User can search and visualize the data in the data base by accessing WWW server through the Internet from local machine. Only a browsing software to access WWW should be prepared. It enables us to easily search data of spent fuel composition if we can access the Internet. This system can be operated on WWW server machine which supports use of Common Gateway Interface (CGI). This report describes the background of the development of SFCOMPO on W3 and is it`s user`s manual. (author)

  17. 40Ar/39Ar dating and zircon chronochemistry for the Izu-Bonin rear arc, IODP site U1437

    Science.gov (United States)

    Schmitt, A. K.; Konrad, K.; Andrews, G. D.; Horie, K.; Brown, S. R.; Koppers, A. A. P.; Busby, C.; Tamura, Y.

    2016-12-01

    The scientific objective of IODP Expedition 350 drilling at Site U1437 (31°47.390'N, 139°01.580'E) was to reveal the "missing half of the subduction factory": the rear arc of a long-lived intraoceanic subduction zone. Site U1437 lies in a 50 km long and 20 km wide volcano-bounded basin, 90 km west of the Izu arc front, and is the only IODP site drilled in the rear arc. The Izu rear arc is dominated by Miocene basaltic to dacitic seamount chains, which strike at a high angle to the arc front. Radiometric dating targeted a single igneous unit (1390 mbsf), and fine to coarse volcaniclastic units for which we present zircon and 40Ar/39Ar (hornblende, plagioclase, and groundmass) age determinations. All zircons analyzed as grain separates were screened for contamination from drill-mud (Andrews et al., 2016) by analyzing trace elements and, where material was available, O and Hf isotope compositions. Igneous Unit 1 is a rhyolite sheet and yielded concordant in-situ and crystal separate U-Pb zircon ages (13.7±0.3 Ma; MSWD = 1.3; n = 40 spots), whereas the 40Ar/39Ar hornblende plateau age (12.9±0.3; MSWD = 1.1; n = 9 steps) is slightly younger, possibly reflecting pre-eruptive zircon crystallization, or alteration of hornblende. U-Pb zircon and 40Ar/39Ar plateau ages from samples above igneous Unit 1 are concordant with biostratigraphic and paleomagnetic ages (available to 1300 mbsf), but plagioclase and groundmass samples below 1300 m become younger with depth, hinting at post-depositional alteration. A single zircon from 1600 mbsf yielded a U-Pb age of 15.4±1.8 Ma; its trace element composition resembles other igneous zircons from U1437, and is tentatively interpreted as a Middle Miocene age for the lowermost lithostratigraphic unit VII. Oxygen and Hf isotopic values of igneous zircon indicate mantle origins, with some influence of assimilation of hydrothermally altered oceanic crust evident in sub-mantle oxygen isotopic compositions. Lessons from site U1437 are

  18. Metabolism of a new synthetic progestagen, Org 2969, in female volunteers

    International Nuclear Information System (INIS)

    Viinikka, L.; Ylikorkala, O.; Vihko, R.; Hasenack, H.G.; Nieuwenhuyse, H.

    1980-01-01

    The metabolism of a new synthetic progestagen, Org 2969 was studied in 4 healthy female volunteers. During the first part of the study (Phase I), the volunteers ingested 50 μg (about 0.1 mCi) of [16- 3 H]Org 2969 together with 50 μg of ethinyloestradiol as a single dose. During the second part of the study (Phase II), a 10-day pre-treatment with the same dosage of non-radioactive compound preceded the administration of the radioactive steroid. A peak level of total radioactivity, representing 3.16-5.02% of the dose given/l of serum, was achieved within 2-3 h in Phase I. During Phase II, the corresponding figures were 4.54-5.13% after 1.5-3 h. The difference was mainly due to an increase of freely-extractable steroids during Phase II. The difference can at least partly be explained by assuming a change in the kinetics of the metabolism of Org 2969 by pre-treatment with Org 2969 and ethinyloestradiol. The mean recovery of radioactivity in urine and faeces was 83.0%/48.1%/34.9% (total/urine/faeces) of the total dose in Phase I and 76.1%/45.2%/30.9% during Phase II. The differences in the total excretion and in the radioactivity excreted in the faeces were significant. (author)

  19. 40Ar/39Ar dating of Quaternary volcanic ashes by multi-collection noble gas mass spectrometry: protocols, precision and intercalibration

    DEFF Research Database (Denmark)

    Storey, Michael; Rivera, Tiffany; Flude, Stephanie

    ) higher mass resolution allows hydrocarbon interferences to be pseudo resolved for the different argon isotopes; and (iv) multi-collection, allowing more data to be gathered in a fixed time in comparison with single-collector peak-switching measurements. We evaluate (i) protocols for detector inter......The recent availability of commercial high-resolution, multi-collector, noble gas mass spectrometers equipped with ion-counting electron multipliers provides new opportunities for improved precision in 40Ar/39Ar dating. This is particularly true for single crystal dating of Quaternary aged samples...... where potassium-bearing phenocrysts may contain relatively small amounts of radiogenic 40Ar. In 2005, the Quaternary Dating Laboratory, Roskilde University, installed a Nu-Instruments multi-collector Noblesse noble gas mass spectrometer, which is configured with a Faraday detector and three ion...

  20. Fuel Reduction for the Mobility Air Forces

    Science.gov (United States)

    2015-01-01

    charitable contribution at www.rand.org/giving/contribute www.rand.org Library of Congress Control Number: 2015931912 ISBN: 978-0-8330-8765-2 For more...OPD. Figure 3.5. Comparison of Continuous and Conventional Descent Approaches SOURCE: Adapted from the European Organisation for the Safety of