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Sample records for 8-week period participants

  1. Home grocery delivery improves the household food environments of behavioral weight loss participants: Results of an 8-week pilot study

    Directory of Open Access Journals (Sweden)

    Niemeier Heather M

    2007-11-01

    Full Text Available Abstract Background Household food availability is consistently linked to dietary intake; yet behavioral weight control treatment includes only minimal instruction on how to change the home environment to support dietary goals. This pilot study examined whether it is feasible to change the household food environments of behavioral weight loss participants through the use of a commercially available grocery home delivery service. Methods Overweight participants (N = 28; BMI = 31.7 ± 3.6 kg/m2; 89.3% women, 47.9 ± 9.5 years were randomly assigned to 8-weeks of standard behavioral weight loss (SBT or to SBT plus home food delivery (SBT+Home. SBT+Home participants were instructed to do their household grocery shopping via an online service affiliated with a regional supermarket chain and were reimbursed for delivery charges. Results Compared to SBT, SBT+Home produced significantly greater reductions in the total number of foods in the home (p = .01 and number of foods that were high in fat (p = .002. While the groups did not differ in 8-week weight losses, within SBT+Home there was a trend for the number of home deliveries to be associated with weight loss (p = .08. Participants reported that the home delivery service was easy to use and that it helped decrease impulse purchases and lead to healthier choices; however, few planned to continue using the service after the study. Conclusion Encouraging weight loss participants to use a commercially available online grocery ordering and home delivery service reduces the overall number of food items in the home and decreases access to high-fat food choices. More research is needed to determine whether this is a viable strategy to strengthen stimulus control and improve weight loss outcomes.

  2. The effect on cardiorespiratory fitness after an 8-week period of commuter cycling - A randomized controlled study in adults

    DEFF Research Database (Denmark)

    Møller, Niels Christian; Østergaard, Lars; Gade, Jens Raaberg

    2011-01-01

    change in lifestyle" or to "minimum 20minutes of daily commuter cycling during 8weeks". Maximal oxygen uptake was assessed directly during a progressive cycle-ergometer-test, sum of skinfolds was used as an estimate of body fat, and blood pressure was measured using a Dinamap monitor. Measurements were...

  3. Safety and efficacy of an 8-week regimen of grazoprevir plus ruzasvir plus uprifosbuvir compared with grazoprevir plus elbasvir plus uprifosbuvir in participants without cirrhosis infected with hepatitis C virus genotypes 1, 2, or 3 (C-CREST-1 and C-CREST-2, part A)

    DEFF Research Database (Denmark)

    Gane, Edward J; Pianko, Stephen; Roberts, Stuart K

    2017-01-01

    BACKGROUND: New hepatitis C virus (HCV) therapies with pan-genotypic efficacy are needed. The goals of part A of C-CREST-1 and C-CREST-2 were to compare the efficacies of two doses (300 mg or 450 mg once daily) of uprifosbuvir (MK-3682; NS5B inhibitor) in an 8-week regimen combined with grazoprev...

  4. CAN 8-WEEKS OF TRAINING AFFECT ACTIVE DRAG IN YOUNG SWIMMERS?

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    Daniel A. Marinho

    2010-03-01

    Full Text Available The aim of this study was to assess the effects of 8-weeks of training on active drag in young swimmers of both genders. Eight girls and twelve boys' belonging to the same swimming team and with regular competitive participation in national and regional events for the previous two seasons participated in this study. Active drag measurements were conducted in two different evaluation moments: at the beginning of the season and after 8 weeks of training (6.0 ± 0.15 training units per week, 21.00 ± 3.23 km per week and 3.50 ± 0.23 km per training unit. The maximal swimming velocity at the distance of 13 m, active drag and drag coefficient were measured on both trials by the method of small perturbations with the help of an additional hydrodynamic body. After 8 weeks of training, mean active drag (drag force and drag coefficient decreased in girls and boys, although no significant differences were found between the two trials. It seems that 8 weeks of swimming training were not sufficient to allow significant improvements on swimming technique

  5. Effect on Oxygen Cost of Transport from 8-Weeks of Progressive Training with Barefoot Running.

    Science.gov (United States)

    Tam, N; Tucker, R; Astephen Wilson, J L; Santos-Concejero, J

    2015-11-01

    Popular interest in barefoot running has emerged as a result of its alleged performance and injury prevention benefits. Oxygen cost of transport (COT) improvements from barefoot running, however, remains equivocal. The aim of this study was to determine the influence of an 8-week progressive barefoot training program on COT and associated spatiotemporal variables. 15 male runners participated in this study. Variables such as oxygen uptake, biomechanical and spatiotemporal characteristics of gait, including ground contact (GC) and swing time; stride length and frequency and ankle plantar-dorsiflexion were measured pre- and post-intervention. The COT did not differ between barefoot and shod running either pre- or post-training. Improved barefoot COT (pbarefoot and shod conditions persisted over the training period. A decrease in barefoot COT was associated with a decrease in GC time (p=0.003, r=0.688) and a small increase in stride frequency (p=0.030; r=0.569). Ground contact time and stride frequency, previously associated with COT, only partly contribute (32% - Stride frequency and 47% - GC time) to a decrease in COT after barefoot training. Thus other physiological and biomechanical variables must influence the improvement in COT after a barefoot training intervention.

  6. Pain rehabilitation – outcome of an 8-week rehabilitation program

    Directory of Open Access Journals (Sweden)

    Norrefalk J.R.

    2012-10-01

    Full Text Available The prevalence of persistent pain has been estimated to be around 20-50% in a normal population. Musculoskeletal related pain is the most common form of persistent pain. In patients with persistent pain there are alterations in the peripheral as well as the central nervous system and patients develop a dysfunctional behaviour which, in many cases, leads to severe suffering for the patient. In the European countries an increasing problem has emerged consisting of more people on long-term sick-leave, increased number of early retirements and high social costs. After an 8-week structured multiprofessional rehabilitation programme at the Karolinska Institute in Stockholm, Sweden 63% of patients with long-standing non-malignant pain returned to work and half of the patients were still at work at a 6-year follow-up. Half of the patients reported pain reduction and almost half of the patients had reduced their consumption of analgesics. The rehabilitation program was estimated as economically beneficial on a society level. It is concluded that pain rehabilitation should have a multiprofessional approach. Pain rehabilitation programs are beneficial for the possibility for the patient to return to work pain and leads to pain reduction in the long run. Furthermore, they are beneficial from a socio-economical aspect.

  7. Follow up of some anthropometric and ergometric parameters during 8 week resistance training

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    Drapšin Miodrag

    2009-01-01

    Full Text Available Muscle cell adaptation to physical activity is well known. Hypertrophy is one of the basic changes but metabolic changes are following the anatomic ones as well. The aim of the study was to follow up the changes of the ergometric parameters and surface area of the thigh muscles evoked by the heavy resistance strength training. The study included 15 male subjects, who took part in the heavy resistance strength training lasting 8 weeks. Anthropometric (surface area of the thigh muscles and ergometric (peak power parameters were measured at the beginning and at the end of the 8 week period in order to evaluate the changes in the thigh muscles. The surface area of the thigh muscles increased significantly (p<0.05 (the left leg 9.26±0.32 cm2 and the right leg 9.07±0.57 cm2. Metabolic changes were assessed via Wingate test and also showed significant increase (p<0.05. This finding indirectly indicates the increase in anaerobic capacity of the trained muscles. The heavy resistance training evidently influenced the changes in the trained muscles. After the 8 week period both antropometric and metabolic changes were evident, and significant.

  8. The activity of satellite cells and myonuclei following 8 weeks of strength training in young men with suppressed testosterone levels

    DEFF Research Database (Denmark)

    Kvorning, T; Kadi, F; Schjerling, P

    2015-01-01

    AIM: To investigate how suppression of endogenous testosterone during an 8-week strength training period influences the activity of satellite cells and myonuclei. METHODS: Twenty-two moderately trained young men participated in this randomized, placebo-controlled, and double-blinded intervention...... from the mid-portion of the vastus lateralis muscle. RESULTS: Testosterone resting level in goserelin was 10-20 times lower compared with placebo, and the training-induced increase in the level of testosterone was abolished in goserelin. Training increased satellite cells number in type II fibres by 20......% in placebo and by 52% in goserelin (P cells and myonuclei were seen in type I fibres in either group. Data from the microarray analysis...

  9. EFFECT OF 8 WEEKS OF AEROBIC ON BODY COMPOSITION AND BLOOD PRESSURE IN POSTMENOPAUSAL WOMEN

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    Shahram Gholamrezai

    2014-10-01

    Full Text Available Aim: Nowadays increasing blood pressure is the most important risk factor of coronary, cerebral and renal vessel diseases. Epidemiological studies indicate that Physical inactivity adversely affects the blood pressure in postmenopausal women. The purpose of this study was to determine the impact of aerobic on body composition and blood pressure in postmenopausal women. Methods: 20 healthy postmenopausal women with similar age and weight were randomly devided in intervention and control groups. Subjects completed an informed consent form and health history questionnaire. The intervention group was trained in an aerobic exercise program for 8 weeks (3 sessions weekly. Weight, body fat percentage (BF%, body mass index (BMI, waist to hip ratio (WHR, Lean body mass and blood pressure (BP were measured in the beginning and the end of the study for all of the subjects. Data were analyzed by the Paired t-test and independent t- test. Results: The results showed that BF% , WHR, BMI decreased and Lean body mass increased significantly in training group after 8 weeks training (P0.05. Conclusions: It seems that a period of aerobic training for 8 weeks can be effective as a non-pharmacological treatment strategy for improvement some physical fitness and body composition indexes, blood pressure in postmenopausal women.

  10. Effects of 8 weeks of mat-based Pilates exercise on gait in chronic stroke patients.

    Science.gov (United States)

    Roh, SuYeon; Gil, Ho Jong; Yoon, Sukhoon

    2016-09-01

    [Purpose] The purpose of this study was to investigate the effects of an 8-week program of Pilates exercise on gait in chronic hemiplegia patients and to determine whether or not it can be used for rehabilitation in postsrtoke patients. [Subjects and Methods] Twenty individuals with unilateral chronic hemiparetic stroke (age, 66.1 ± 4.4 yrs; height, 162.3 ± 8.3 cm; weight, 67.4 ± 12.3 kg) participated in this study and were randomly allocated equally to either a Pilates exercise group or a control group. To identify the effects of Pilates exercise, a 3-D motion analysis with 8 infrared cameras was performed. [Results] For the gait parameters, improvements were found in the Pilates exercise group for all variables, and statistical significance was observed for stride length, gait velocity, knee range of motion and hip range of motion. For the asymmetry indexes, insignificant improvements were found for all variables in the Pilates exercise group. [Conclusion] In conclusion, an 8-week program of Pilates exercise had a positive influence on improving the gait ability of poststroke patients, and the intervention could be applied to poststroke patients with various levels of physical disability by adjusting the intensity of training.

  11. Effects of 8 weeks of mat-based Pilates exercise on gait in chronic stroke patients

    Science.gov (United States)

    Roh, SuYeon; Gil, Ho Jong; Yoon, Sukhoon

    2016-01-01

    [Purpose] The purpose of this study was to investigate the effects of an 8-week program of Pilates exercise on gait in chronic hemiplegia patients and to determine whether or not it can be used for rehabilitation in postsrtoke patients. [Subjects and Methods] Twenty individuals with unilateral chronic hemiparetic stroke (age, 66.1 ± 4.4 yrs; height, 162.3 ± 8.3 cm; weight, 67.4 ± 12.3 kg) participated in this study and were randomly allocated equally to either a Pilates exercise group or a control group. To identify the effects of Pilates exercise, a 3-D motion analysis with 8 infrared cameras was performed. [Results] For the gait parameters, improvements were found in the Pilates exercise group for all variables, and statistical significance was observed for stride length, gait velocity, knee range of motion and hip range of motion. For the asymmetry indexes, insignificant improvements were found for all variables in the Pilates exercise group. [Conclusion] In conclusion, an 8-week program of Pilates exercise had a positive influence on improving the gait ability of poststroke patients, and the intervention could be applied to poststroke patients with various levels of physical disability by adjusting the intensity of training. PMID:27799706

  12. Early antenatal diagnosis of spina bifida presenting with a "step" in the posterior contour of an 8-week embryo.

    Science.gov (United States)

    Lulla, Chander; Hegde, Amogh; Shah, Jatin; Sheth, Jayesh

    2008-01-01

    We report a case of spina bifida in the upper thoracic spine with an accompanying meningocoele suspected at 8 weeks' gestation via transvaginal sonography and confirmed at 13 weeks' gestation via 3-dimensional sonography. The fetal cranial vault and intracranial structures were normal. The only finding in the 8-week sonogram was a subtle angulation or "step" in the posterior contour of the embryo; this may be attributed to kyphosis, which often accompanies this condition. The presence of a "step" in the fetal contour must alert the sonologist to the possibility of spina bifida. To our knowledge, this is the earliest antenatal diagnosis of spina bifida. (c) 2007 Wiley Periodicals, Inc.

  13. Initial weight loss on an 800-kcal diet as a predictor of weight loss success after 8 weeks

    DEFF Research Database (Denmark)

    Handjieva-Darlenska, T.; Handjiev, S.; Larsen, Thomas Meinert

    2010-01-01

    The purpose of this study was to investigate whether pre-treatment subject characteristics and weight change during the first weeks of a low-calorie diet (LCD) can predict weight loss outcomes at the end of a controlled 8-week weight loss period in overweight and obese adults....

  14. Changes in the latencies of visual-evoked potentials in people undergoing tennis training Dynamic comparison before and after 8 weeks training

    Institute of Scientific and Technical Information of China (English)

    Jingguo Zhao; Shujuan Pang

    2008-01-01

    BACKGROUND: Some previous studies have shown that exercise is an important factor that affects the latencies of visual-evoked potentials (VEPs).OBJECTIVE: To investigate the effects of spending a period of time undergoing tennis training on the latencies of VEPs by comparing the latencies of VEPs before tennis training with those after 8 weeks of tennis training.DESIGN, TIME AND SETTING: The non-randomly concurrent controlled experiment was performed in the Department of Human Movement Sciences, Physical Education College, Shandong Normal University from April to June 2007.PARTICIPANTS: In total, 45 healthy volunteers from Shandong Normal University were selected as subjects, including 31 students majoring in physical education (11 males and 5 females participated in the tennis training plan for 8 weeks), and 14 students from other subjects. Informed consent was obtained. According to whether they were majoring in physical education or not, and whether or not they took part in tennis training, the students were divided into 3 groups: a tennis group of physical education students (n =16), a non-tennis group of physical education students (n =15) and a non-tennis group of non-physical education students (n =14). METHODS: The subjects in the tennis group took part in a regular tennis training plan of 2 hours a day and 3 days per week, for 8 weeks, while the subjects in two non-tennis groups were not in the tennis training plan. The NDI-200 neural electricity tester (Shanghai Haishen Medical Electronic Instrument Co., Ltd.) was used to measure VEPs before and after the experiment in all three groups, and to compare the latencies of VEPs recorded before training with those recorded after training.MAIN OUTCOME MEASURES: Comparison of the changes in latencies of VEPs before and after 8 weeks of tennis training.RESULTS: All 45 subjects finished the test and datas from all were included in the statistical analysis. There were no significant differences among all the three

  15. Improvement of Interoceptive Processes after an 8-Week Body Scan Intervention

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    Dana Fischer

    2017-09-01

    Full Text Available Objective: Interoceptive processes are defined as ability to detect sensations arising within the body. There is a growing body of research investigating ways of improving interoceptive processes. One promising approach increasing the attention to bodily sensations is the body scan (BS, a method stemming from mindfulness-based stress reduction. Research so far revealed only heterogenous findings of meditational practice and mindfulness-based stress reduction on interoceptive processes. Even more importantly, there is no study considering the effect of an 8-week BS intervention on interoceptive processes and the distinguishable subdomains of interoception. Therefore, the main objective of this research is to examine the effects of a BS intervention on different interoceptive subdomains over 8 weeks of training in two different samples.Methods: In study 1, healthy participants executed a 20 min standardized audiotaped BS in the BS intervention group (n = 25 each day over 8 weeks. The control group (n = 24 listened to an audio book for the same amount of time. In study 2, the BS group (n = 18 was compared to an inactive control group (n = 18. In both studies, three measurement points were realized and interoceptive accuracy (IAc – using a heartbeat perception task – as well as interoceptive sensibility (IS – using confidence ratings for the heartbeat perception task and the subscale ‘interoceptive awareness’ of the Eating Disorder Inventory-2 (EDI-2 – were assessed.Results: In study 1, we found, as a descriptive trend, IAc and confidence ratings to be increased irrespective of the condition. However, post hoc analysis revealed a significant improvement of IAc between T1 and T3 in the BS intervention only. IS revealed to be unaffected by the interventions. In study 2, we observed a significant positive effect of the BS intervention on IAc and confidence ratings compared to the inactive controls. As in study 1, IS (EDI-2 was unaffected by

  16. Changes in cerebral blood flow and anxiety associated with an 8-week mindfulness programme in women with breast cancer.

    Science.gov (United States)

    Monti, Daniel A; Kash, Kathryn M; Kunkel, Elisabeth J S; Brainard, George; Wintering, Nancy; Moss, Aleezé S; Rao, Hengyi; Zhu, Senhua; Newberg, Andrew B

    2012-12-01

    This study employed functional magnetic resonance imaging to evaluate changes in cerebral blood flow (CBF) associated with the Mindfulness-based Art Therapy (MBAT) programme and correlate such changes to stress and anxiety in women with breast cancer. Eighteen breast cancer patients were randomized to the MBAT or education control group. The patients received the diagnosis of breast cancer between 6 months and 3 years prior to enrollment and were not in active treatment. The age of participants ranged from 52 to 77 years. A voxel-based analysis was performed to assess differences at rest, during meditation and during a stress task. The anxiety sub-scale of the Symptoms Checklist-90-Revised was compared with changes in resting CBF before and after the programmes. Subjects in the MBAT arm demonstrated significant increases in CBF at rest and during meditation in multiple limbic regions, including the left insula, right amygdala, right hippocampus and bilateral caudate. Patients in the MBAT programme also had a significant correlation between increased CBF in the left caudate and decreased anxiety scores. In the MBAT group, responses to a stressful cue resulted in reduced activation of the posterior cingulate. The results demonstrate that the MBAT programme was associated with significant changes in CBF, which correlated with decreased anxiety over an 8-week period.

  17. Effects of 8-Week Training on Aerobic Capacity and Swimming Performance of Boys Aged 12 Years

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    Zarzeczny, Ryszard; Kuberski, Mariusz; Deska, Agnieszka; Zarzeczna, Dorota; Rydz, Katarzyna; Lewandowska, Anna; Balchanowski, Tomasz; Bosiacki, Janusz

    2011-01-01

    Study aim: To assess the effects of 8-week endurance training in swimming on work capacity of boys aged 12 years. Material and methods: The following groups of schoolboys aged 12 years were studied: untrained control (UC; n = 14) and those training swimming for two years. The latter ones were subjected to 8-week training in classical style (CS; n…

  18. The Effect of 8 weeks aerobic exercise and yoga on primary dismenorrhea

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    T Siahpour

    2013-10-01

    Full Text Available Abstract Background & aim: Dysmenorrhea, menstrual cramps without physical pain is a common complaint in gynecology. The aim of this study was to investigate the effect of aerobic training on primary Dysmenorrhea in a period of 8 weeks. Materials & Methods: In the present clinical-trial study, 60 non-athlete girls with primary Dysmenorrhea were randomly divided into three groups: aerobic training, yoga and control groups. Based on the visual analog scale of pain intensity, pain duration and amount of analgesics administered was assessed before and after the period of primary Dysmenorrhea using a questionnaire. In this eight-week exercise program, the aerobic exercises group for 60 minutes in three weeks and yoga exercises group in three sessions per week for 60 minutes, the yoga breathing techniques, exercises, asana and relaxation techniques were performed. There was no intervention in the control group. Data were analyzed by Wilcoxon, Kruskal-Wallis and Mann Whitney (p0.05. There was a significant decrease in the analgesic consumption in the yoga group compared to the exercise group (p<0/05. Conclusion: Both aerobic and yoga are effective in the treatment of primary Dysmenorrhea, but yoga has a greater reduction property on drug dosage. Key words: primary dysmenorrhea, aerobic exercise, yoga exercise, female student

  19. Hatha Yoga Practice Improves Attention and Processing Speed in Older Adults: Results from an 8-Week Randomized Control Trial.

    Science.gov (United States)

    Gothe, Neha P; Kramer, Arthur F; McAuley, Edward

    2017-01-01

    Age-related cognitive decline is well documented across various aspects of cognitive function, including attention and processing speed, and lifestyle behaviors such as physical activity play an important role in preventing cognitive decline and maintaining or even improving cognitive function. The purpose of this study was to evaluate the effects of an 8-week Hatha yoga intervention on attention and processing speed among older adults. Participants (n = 118; mean age, 62 ± 5.59) were randomly assigned to an 8-week Hatha yoga group or a stretching control group and completed cognitive assessments-Attention Network Task, Trail Making Test parts A and B, and Pattern Comparison Test-at baseline and after the 8-week intervention. Analyses of covariance revealed significantly faster reaction times for the yoga group on the Attention Network Task's neutral, congruent, and incongruent conditions (p ≤ 0.04). The yoga intervention also improved participants' visuospatial and perceptual processing on the Trail Making Test part B (p = 0.002) and pattern comparison (p yoga practice that includes postures, breathing, and meditative exercises lead to improved attentional and information processing abilities. Although the underlying mechanisms remain largely speculative, more systematic trials are needed to explore the extent of cognitive benefits and their neurobiological mechanisms.

  20. Effect of 8 weeks of free-weight and machine-based strength training on strength and power performance

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    Wirth Klaus

    2016-12-01

    Full Text Available The aim of this study was to evaluate the effectiveness of free-weight and machine-based exercises to increase different strength and speed-strength variables. One hundred twenty male participants (age: 23.8 ± 2.5 years; body height: 181.0 ± 6.8 cm; body mass: 80.2 ± 8.9 kg joined the study. The 2 experimental groups completed an 8 week periodized strength training program that included 2 training sessions per week. The exercises that were used in the strength training programs were the parallel barbell squat and the leg press. Before and after the training period, the 1-repetition-maximum in the barbell squat and the leg press, the squat jump, the countermovement jump and unilateral isometric force (maximal isometric force and the rate of force development were evaluated. To compare each group pre vs. post-intervention, analysis of variance with repeated measures and Scheffé post-hoc tests were used. The leg press group increased their 1-repetition-maximum significantly (p < 0.001, while in the squat group such variables as 1-repetition-maximum, the squat jump and the countermovement jump increased significantly (p < 0.001. The maximal isometric force showed no statistically significant result for the repeated measures factor, while the rate of force development of the squat group even showed a statistically significant decrease. Differences between the 2 experimental groups were detected for the squat jump and the countermovement jump. In comparison with the leg press, the squat might be a better strength training exercise for the development of jump performance.

  1. An 8-Week Web-Based Weight Loss Challenge With Celebrity Endorsement and Enhanced Social Support: Observational Study

    Science.gov (United States)

    Collins, Clare E; Morgan, Philip J; Callister, Robin

    2013-01-01

    Background Initial engagement and weight loss within Web-based weight loss programs may predict long-term success. The integration of persuasive Web-based features may boost engagement and therefore weight loss. Objective To determine whether an 8-week challenge within a commercial Web-based weight loss program influenced weight loss, website use, and attrition in the short term, when compared to the standard program. Methods De-identified data for participants (mean age 36.7±10.3 years; 86% female) who enrolled in the Biggest Loser Club (BLC) (n=952) and the BLC’s Shannan Ponton Fast Track Challenge (SC) for 8 weeks (n=381) were compared. The BLC program used standard evidence-based website features, with individualized calorie and exercise targets to facilitate a weight loss of 0.5-1 kg per week (–500kcal/day less than estimated energy expenditure). SC used the same website features but in addition promoted greater initial weight loss using a 1200 kcal/day energy intake target and physical activity energy expenditure of 600 kcal/day. SC used persuasive features to facilitate greater user engagement, including offering additional opportunities for social support (eg, webinar meetings with a celebrity personal trainer and social networking) endorsed by a celebrity personal trainer. Self-reported weekly weight records were used to determine weight change after 8 weeks. A primary analysis was undertaken using a generalized linear mixed model (GLMM) with all available weight records for all participants included. Dropout (participants who cancelled their subscription) and nonusage (participants who stopped using the Web-based features) attrition rates at 8 weeks were calculated. The number of participants who accessed each website feature and the total number of days each feature was used were calculated. The difference between attrition rates and website use for the two programs were tested using chi-square and Wilcoxon Rank Sum tests, respectively. Results

  2. An 8-week web-based weight loss challenge with celebrity endorsement and enhanced social support: observational study.

    Science.gov (United States)

    Hutchesson, Melinda J; Collins, Clare E; Morgan, Philip J; Callister, Robin

    2013-07-04

    Initial engagement and weight loss within Web-based weight loss programs may predict long-term success. The integration of persuasive Web-based features may boost engagement and therefore weight loss. To determine whether an 8-week challenge within a commercial Web-based weight loss program influenced weight loss, website use, and attrition in the short term, when compared to the standard program. De-identified data for participants (mean age 36.7±10.3 years; 86% female) who enrolled in the Biggest Loser Club (BLC) (n=952) and the BLC's Shannan Ponton Fast Track Challenge (SC) for 8 weeks (n=381) were compared. The BLC program used standard evidence-based website features, with individualized calorie and exercise targets to facilitate a weight loss of 0.5-1 kg per week (-500kcal/day less than estimated energy expenditure). SC used the same website features but in addition promoted greater initial weight loss using a 1200 kcal/day energy intake target and physical activity energy expenditure of 600 kcal/day. SC used persuasive features to facilitate greater user engagement, including offering additional opportunities for social support (eg, webinar meetings with a celebrity personal trainer and social networking) endorsed by a celebrity personal trainer. Self-reported weekly weight records were used to determine weight change after 8 weeks. A primary analysis was undertaken using a generalized linear mixed model (GLMM) with all available weight records for all participants included. Dropout (participants who cancelled their subscription) and nonusage (participants who stopped using the Web-based features) attrition rates at 8 weeks were calculated. The number of participants who accessed each website feature and the total number of days each feature was used were calculated. The difference between attrition rates and website use for the two programs were tested using chi-square and Wilcoxon Rank Sum tests, respectively. Using GLMM, including weight data for all

  3. Impact of 8-week endurance training on qualitative and quantitative parameters of stroke volume

    Directory of Open Access Journals (Sweden)

    Suzana Pustivšek

    2014-08-01

    Full Text Available Background: Dynamics of stroke volume during increasing progressive load varies widely among individuals. The data of current studies describing the impact of long-term endurance training on the dynamics of cardiac stroke volume are conflicting. The purpose of this study was to evaluate the impact of 8-week endurance training on the dynamics of stroke volume and some quantitative features of cardiac function in recreational female runners.Methods: Measurements were performed in the physiological laboratory at the Institute of Sport, Faculty of Sport in Ljubljana. CosmedK4b2 equipment that allows continuous “on-line”, “breath-by-breath” monitoring of oxygen consumption and gases in exhaled air was used. Cardiac output was calculated by the method described by Stringer et al.Results: The results showed a significant increase in stroke volume at rest and during the first two minutes of the test. Maximum stroke volume did not increase, but there was a decrease in heart rate during maximal stroke volume from 126.65 (± 27.14 to 120.15 (± 26.56 beats per minute. The dynamics of stroke volume in a majority of participants did not change. The most common dynamics of stroke volume before and after test was plateau dynamics. The training resulted in an increase in running endurance and the average increase in running speed during the final test by 4.41 % (± 4.62.Conclusion: The exercise resulted in minimal changes in cardiac function and a significant improvement in endurance parameters.

  4. Obesity-related beliefs predict weight loss after an 8-week low-calorie diet

    NARCIS (Netherlands)

    Wamsteker, E.W.; Geenen, R.; Iestra, J.A.; Larsen, J.K.; Zelissen, P.M.J.; Staveren, van W.A.

    2005-01-01

    The objective of this study was to examine whether beliefs about the cause, consequences, time line, and control of obesity are predictors of the amount of weight loss after an 8-week, low-calorie diet consisting of meal replacements. Forty-eight women and 18 men, mean age=45.9 (range=23 to 73

  5. Obesity-related beliefs predict weight loss after an 8-week low-calorie diet

    NARCIS (Netherlands)

    Wamsteker, E.W.; Geenen, R.; Iestra, J.A.; Larsen, J.K.; Zelissen, P.M.J.; Staveren, van W.A.

    2005-01-01

    The objective of this study was to examine whether beliefs about the cause, consequences, time line, and control of obesity are predictors of the amount of weight loss after an 8-week, low-calorie diet consisting of meal replacements. Forty-eight women and 18 men, mean age=45.9 (range=23 to 73 years

  6. Obesity-related beliefs predict weight loss after an 8-week low-calorie diet

    NARCIS (Netherlands)

    Wamsteker, E.W.; Geenen, R.; Iestra, J.A.; Larsen, J.K.; Zelissen, P.M.J.; Staveren, van W.A.

    2005-01-01

    The objective of this study was to examine whether beliefs about the cause, consequences, time line, and control of obesity are predictors of the amount of weight loss after an 8-week, low-calorie diet consisting of meal replacements. Forty-eight women and 18 men, mean age=45.9 (range=23 to 73 years

  7. Initial weight loss on an 800-kcal diet as a predictor of weight loss success after 8 weeks: the Diogenes study

    DEFF Research Database (Denmark)

    Handjieva-Darlenska, T; Handjiev, S; Larsen, Thomas Meinert

    2010-01-01

    The purpose of this study was to investigate whether pre-treatment subject characteristics and weight change during the first weeks of a low-calorie diet (LCD) can predict weight loss outcomes at the end of a controlled 8-week weight loss period in overweight and obese adults.......The purpose of this study was to investigate whether pre-treatment subject characteristics and weight change during the first weeks of a low-calorie diet (LCD) can predict weight loss outcomes at the end of a controlled 8-week weight loss period in overweight and obese adults....

  8. Effects of 8 Weeks of Aerobic Exercise on Matrix Metalloproteinase-9 and Tissue Inhibitor Levels in Type II Diabetic Women

    Directory of Open Access Journals (Sweden)

    Mostafa Dastani

    2014-06-01

    Full Text Available Background: Increased vascular stiffness is a marker of atherosclerosis, which is diagnosed in the early stages of diabetes II. Matrix metalloproteinases (MMPs and their tissue inhibitors (TIMPs are a family of proteolytic enzymes necessary for structure and function of great vessels. This study examined the effects of 8 weeks of aerobic exercise on MMPR9R and TIMP-1 levels in type II diabetic women. Materials and Methods: This is a quasi-experimental study which included 20 in type II diabetic women with mean age of 53.2±2.5 years, body mass index (BMI of 28.73±2.27 and fat percentage of 30.6±2.05, who were randomly divided into two groups: aerobic exercise group (8 weeks, 3 sessions per week for 50 minutes and control group. To examine changes in MMPR9R and TIMP-1, 5 ml of blood was taken from the brachial vein of patients before and 48 hours after completion of exercise period and after 12 hours of fasting at rest. Data analysis was performed using SPSS-16 software with the independent and paired t-tests. Results: A significant decrease was observed in body mass index and body fat percentage in the experimental group (p<0.05. Compared with the control group, the aerobic exercise group showed a significant decrease in MMPR9R (p=0.01 and a significant increase in TIMP-1 levels (p=0.02 after 8 weeks of aerobic exercise. Conclusion: The results showed that aerobic exercise as a stimulus can change the levels of matrix metalloproteinases and their tissue inhibitors in order to prevent cardiovascular diseases in diabetics.

  9. Changes in corticospinal transmission following 8 weeks of ankle joint immobilization

    DEFF Research Database (Denmark)

    Leukel, Christian; Taube, Wolfgang; Rittweger, Jörn;

    2015-01-01

    ) of the primary motor cortex (Hcond). This method allows assessment of transmission in fast (monosynaptic) and slow(er) (polysynaptic) corticospinal pathways. METHODS: 9 subjects underwent 8weeks of unilateral ankle joint immobilization during daytime, 7 subjects served as controls. The measures obtained before...... immobilization. Importantly, Hcond revealed significant facilitation of conditioned reflexes, but only for longer conditioning intervals, suggesting that immobilization increased excitability only of slower, indirect corticospinal pathways. No changes were observed in the control group. Immobilization had...... no significant effects on spinal reflex measures. CONCLUSIONS: 8weeks of ankle joint immobilization was accompanied by pathway-specific modulation of corticospinal transmission. SIGNIFICANCE: It is particularly interesting that fast corticospinal projections were unaffected as these are involved in controlling...

  10. Effect of sand versus grass training surfaces during an 8-week pre-season conditioning programme in team sport athletes.

    Science.gov (United States)

    Binnie, Martyn John; Dawson, Brian; Arnot, Mark Alexander; Pinnington, Hugh; Landers, Grant; Peeling, Peter

    2014-01-01

    This study compared the use of sand and grass training surfaces throughout an 8-week conditioning programme in well-trained female team sport athletes (n = 24). Performance testing was conducted pre- and post-training and included measures of leg strength and balance, vertical jump, agility, 20 m speed, repeat speed (8 × 20 m every 20 s), as well as running economy and maximal oxygen consumption (VO2max). Heart rate (HR), training load (rating of perceived exertion (RPE) × duration), movement patterns and perceptual measures were monitored throughout each training session. Participants completed 2 × 1 h conditioning sessions per week on sand (SAND) or grass (GRASS) surfaces, incorporating interval training, sprint and agility drills, and small-sided games. Results showed a significantly higher (P training load in the SAND versus GRASS group throughout each week of training, plus some moderate effect sizes to suggest lower perceptual ratings of soreness and fatigue on SAND. Significantly greater (P training surfaces throughout an 8-week conditioning programme can significantly increase the relative exercise intensity and training load, subsequently leading to superior improvements in aerobic fitness.

  11. CONCURRENT TRAINING IN PREPUBESCENT CHILDREN: THE EFFECTS OF 8 WEEKS OF STRENGTH AND AEROBIC TRAINING ON EXPLOSIVE STRENGTH AND V_O2MAX

    OpenAIRE

    Alves, Ana; Marta, Carlos; Neiva, Henrique; Izquierdo, Mikel; Marques, Mário

    2016-01-01

    Concurrent training in prepubescent children: the effects of 8 weeks of strength and aerobic training on explosive strength and V_ O2max. J Strength Cond Res 30(7): 2019–2032, 2016— The purpose of this study was to compare the effects of 8-week training periods of strength training alone (GS), combined strength and aerobic training in the same session (GCOM1), or in 2 different sessions (GCOM2) on explosive strength and maximal oxygen uptake (V_ O2max) in prepubescent children. Of note, 168 h...

  12. 10 CFR 603.655 - Frequency of periodic audits of for-profit participants.

    Science.gov (United States)

    2010-01-01

    ... INVESTMENT AGREEMENTS Award Terms Affecting Participants' Financial, Property, and Purchasing Systems Financial Matters § 603.655 Frequency of periodic audits of for-profit participants. If an expenditure-based... during the first year of the award, when the participant has its IPA do its next financial statement...

  13. Interaction Effect of 8-Week Aerobic Exercise and Omega-3 Fatty Acid

    Directory of Open Access Journals (Sweden)

    Gholamreza Khedri

    2013-03-01

    Full Text Available Background: Scientific evidence indicates the impact of aerobic exercise and omega-3 fatty acids - both –are for the improvement of the cardiovascular system .The purpose of this research was about studies interaction effect of 8 weeks aerobic exercise and omega- 3 fatty acids supplementation on plasma adiponectin concentration of elderly men.Materials and Methods: In this study, 36 male non-athletes aged were between 50 to 70 year age range of men aged the city of Genaveh. Statistical sample of 36 male non- athletes in the age range 50 to 70 years old randomly selected in four groups of nine persons, respectively, the first group: exercise supplemental omega-3, Group II: Exercise placebo group: supplementation with omega-3 groups quarter: placebo. Endurance exercise training program includes 24 sessions and 3 sessions per week, with duration and intensity was determined. (55-70% HRmax. Daily supplements of omega-3 fatty acids were 2 Capsule. Blood samples were taken after fasting 14 hours before the study and 48 hours after the last training session was conducted. The data Kolmogrov-Smirnov, t-test, One-Way Anova at significance level of p≤ 0.05 were analyzed in SPSS 17. Results: The results of research after 8 weeks showed that moderate-intensity aerobic exercise and omega-3 fatty acids supplementation, only increased in the exercise + omega-3 fatty acids group (7.8% that could not created a significant increase in plasma adiponectin concentration groups. Also in final of research did not show a significant difference between groups in compare after 8 weeks. Conclusion: The results showed that by aerobic exercise and use of omega-3 fatty acids and increase amounts of adiponectin and its anti boil property, perhaps maybe that, adiponectin by effect of its preservation has a great role in prevention and reduce of cardiovascular diseases.

  14. Prevalence of urinary tract infection in 2-8-week-old infants with jaundice

    Directory of Open Access Journals (Sweden)

    Partini P. Trihono

    2012-09-01

    Full Text Available Background Urinary tract infections (UTI in infants may manifest in various ways and often appear without symptoms. Previous studies have reported that jaundice has been observed in infants aged less than reported that jaundice has been observed in study in the prevalence of UTI in infants with jaundice aged 2-8 weeks is warranted in order to improve diagnosing capability and provide prompt treatment. Objective To investigate the prevalence and profiles of UTI in infants with jaundice aged 2-8 weeks. Methods This cross-sectional study was carried out in June-December 2011 in infants with jaundice aged 2-8 weeks, Subjects were patients from the Epartment of Child Health, Cipto Mangunkusumo Hospital (CMS, as well as the Pediatric Polyclinics of Budi Kemuliaan and Thamrin Hospitals. All subjects underwent total, direct and indirect bilirubin examinations, urinalyses and urine cultures. Results Of the 110 subjects recruited, the prevalence of UTI was 18.2%. More boys than girl had UTIs (13 boys, 7 girls. The microorganism found in subjects with UTIs were Escherichia coli (10/20Klebsiella pneumoniae (8/20, and Enterobacter aerogenes (2/20. Indirect hyperbilirubenia was found in 5/20 subjects. There were more subjects with UTIs in the non-exclusively breastfed (8/20 and non-breastfed (8/20 groups than in the exclusively breastfed group (4/20, the full term gestational age (GA group (17/20 than the preterm GA group (3/20, and the normal birth weight group (15/20 than the low birth weight group (5/20. The median age of jaundice onset was 3.5 days (range 1-40 days, and the median duration of jaundice was 13.5 days (range 3-56 days. Conclusion The prevalence of UTI in infants aged 2-8 weeks with jaundice was 18.2%. More boys than girls had UTIs. The most common infecting microorganism found in our subjects was Escherichia coli. In daily medical practice, infants with prolonged jaundice of more than 2 weeks should be tested by urinalysis and urine cultures

  15. Long-term overactivity in the abdominal oblique muscles after 8 weeks bed-rest- possible implications for musculosketletal health

    Science.gov (United States)

    Belavy, D. L.; Richardson, C. A.; Wilson, S.; Darnell, R.; Hides, J.; Toppenberg, R.; Elmann-Larsen, B.; Rittweger, J.; Felsenberg, D.

    2005-08-01

    Changes in the human lumbo-pelvic (LP) muscles with unloading has received little attention in microgravity research, even though this body region has evolved with the development of upright posture in 1-g. This study used a specific movement task to examine the function of four LP muscles during 8-weeks of bed-rest and one-year follow-up. The main finding was the development of overactivity in the abdominal internal oblique muscle in the follow-up period. This finding implies that the L-P muscle changes occurring during bedrest do not recover on return to the 1-g environment. These results may have implications for musculo-skeletal health for those in sedentary lifestyles on Earth.

  16. Supplementary management of benign prostatic hypertrophy with Prostaquil. An 8-week registry.

    Science.gov (United States)

    Belcaro, G; Dugall, M; Luzzi, R; Ledda, A; Pellegrini, L; Hosoi, M; Errichi, B M; Francis, S; Cornelli, U

    2015-10-22

    The aim of this registry was to evaluate the management of initial symptoms of benign prostatic hyperthrophy (BPH) in otherwise healthy subjects, using Prostaquil® (Alchem) in a 8-week registry. Prostaquil was used at the dosage of 200 mg/day. The product includes Pygeum extract (100 mg) and Saw palmetto oil (35 mg). The two resulting groups standard management and supplement) were comparable. No side effects or comparability problems were observed and compliance was optimal with more than 95% of the capsules correctly used. Empting, frequency, intermittency, urgency, weak flow, straining, nocturia were all significantly improved with Prostaquil (p<0.05) and the improvement - globally and evaluating any single item - was significantly superior to the one observed in controls (p<0.05). Quality of life with the supplement was also significantly better in comparison with controls (p<0.05). The residual vescical volume was 94.7;5,8 ml in the supplement group at inclusion and decreased to 39.3;5 ml (p<0.05) at 8 weeks. This decrease was equivalent to a reduction of 58.5%(vs a decrease of 27.9% in controls)(p<0.05; ANOVA). In conclusion, the most common symptoms of BPH are controlled by Prostaquil a new standardized supplement including Pygeum.

  17. Urinary tract infections in febrile infants younger than 8 weeks of age.

    Science.gov (United States)

    Crain, E F; Gershel, J C

    1990-09-01

    In this prospective study of 442 infants younger than 8 weeks of age who attended a pediatric emergency department with temperature greater than or equal to 100.6 degrees F (38.1 degrees C), urinary tract infections (UTIs) were found in 33 patients (7.5%), 2 of whom were bacteremic. Clinical and laboratory data were not helpful for identifying UTIs. Of the 33 patients with UTIs, 32 had urinalyses recorded; 16 were suggestive of a UTI (more than five white blood cells per high-power field or any bacteria present). Of the 16 infants with apparently normal urinalysis results, three had an emergency department diagnosis suggesting an alternative bacterial focus of infection. If the physician had decided on the basis of apparently normal urinalysis results to forgo obtaining a urine culture, more than half of the UTIs would have been missed. Bag-collected specimens were significantly more likely to yield indeterminate urine culture results than either catheter or suprapubic specimens. In addition, uncircumcised males were significantly more likely to have a UTI than circumcised boys. These results suggest that a suprapubic or catheter-obtained urine specimen for culture is a necessary part of the evaluation of all febrile infants younger than 8 weeks of age, regardless of the urinalysis findings or another focus of presumed bacterial infection.

  18. An 8-week reactive balance training program in older healthy adults:A preliminary investigation

    Institute of Scientific and Technical Information of China (English)

    Max R. Paquette; Yuhua Li; Joseph Hoekstra; Joshua Bravo

    2015-01-01

    Background:This preliminary study examined the effects of an 8-week supervised reactive balance training program on reaction time (RT) and foot speed, static balance and balance confidence in healthy older adults compared to an exercise control group. Methods:Twenty-five older adults were randomly assigned to a reactive balance training group (QuickBoard;n=12;71.0 ± 8.6 years) or a stationary cycling group (control; n = 13; 70.2 ± 6.0 years). Both groups were tested for foot RT foot speed, static balance, and balance confidence at baseline, 4-week, 8-week, and 4-week follow-up. Results: Results indicated significant improvements in QuickBoard foot RT and speed in both groups with greater improvements in the QuickBoard group. However, no group difference was found in static balance performance. Conclusion: Although the improvements in RT and foot speed may be beneficial for fall and trip prevention, the implications of the current findings for trip avoidance and performance of daily tasks are unclear.

  19. Feasibility and Impact of an 8-Week Integrative Yoga Program in People with Moderate Multiple Sclerosis–Related Disability

    Science.gov (United States)

    Kietrys, David; Fogerite, Susan Gould; Silva, Mariella; Logan, Kristen; Barone, Donald A.; Parrott, J. Scott

    2017-01-01

    Background: This pilot study determined the feasibility of a specifically designed 8-week yoga program for people with moderate multiple sclerosis (MS)–related disability. We explored the program's effect on quality of life (QOL) and physical and mental performance. Methods: We used a single-group design with repeated measurements at baseline, postintervention, and 8-week follow-up. Feasibility was examined through cost, recruitment, retention, attendance, and safety. Outcomes included the Multiple Sclerosis Quality of Life Inventory (MSQLI), 12-item Multiple Sclerosis Walking Scale (MSWS-12), Timed 25-Foot Walk test (T25FW), 6-Minute Walk Test (6MWT), Nine-Hole Peg Test (NHPT), Five-Times Sit-to-Stand Test (FTSTS), Multidirectional Reach Test (MDRT), maximum expiratory pressure, and Paced Auditory Serial Addition Test-3″ (PASAT-3″). Results: Fourteen participants completed the study. The program was feasible. There were significant main effects on the 36-item Short Form Health Status Survey Mental Component Summary (SF-36 MCS), Modified Fatigue Impact Scale (MFIS), Bladder Control Scale (BLCS), Perceived Deficits Questionnaire (PDQ), Mental Health Inventory (MHI), MSWS-12, T25FW, NHPT, PASAT-3″, 6MWT, FTSTS, and MDRT-Back. Improvements were found on the SF-36 MCS, MFIS, BLCS, PDQ, MHI, and MSWS-12 between baseline and postintervention. The effect on PDQ persisted at follow-up. Improvements were found on the T25FW, NHPT, 6MWT, FTSTS, and MDRT-Back between baseline and postintervention that persisted at follow-up. The PASAT-3″ did not change between baseline and postintervention but did between postintervention and follow-up. Conclusions: The yoga program was safe and feasible. Improvements in certain measures of QOL and performance were seen at postintervention and follow-up. PMID:28243184

  20. Tolerability, Safety, and Benefits of Risperidone in Children and Adolescents with Autism: 21-Month Follow-up After 8-Week Placebo-Controlled Trial.

    Science.gov (United States)

    Aman, Michael; Rettiganti, Mallikarjuna; Nagaraja, Haikady N; Hollway, Jill A; McCracken, James; McDougle, Christopher J; Tierney, Elaine; Scahill, Lawrence; Arnold, L Eugene; Hellings, Jessica; Posey, David J; Swiezy, Naomi B; Ghuman, Jaswinder; Grados, Marco; Shah, Bhavik; Vitiello, Benedetto

    2015-08-01

    Risperidone has demonstrated efficacy for acute (8 week) and intermediate length (6 month) management of severe irritability and aggression in children and adolescents with autism. Less is known about the long-term effects of risperidone exposure in this population. We examined the tolerability, safety, and therapeutic benefit of risperidone exposure over a 1-2 year follow-up period. In a naturalistic study, 84 children and adolescents 5-17 years of age (from an original sample of 101) were assessed an average of 21.4 months after initial entry into a placebo-controlled 8 week trial of risperidone for children and adolescents with autism and severe irritability. They were assessed at baseline and at follow-up on safety and tolerability measures (blood, urinalysis, electrocardiogram [ECG], medical history, vital signs, neurological symptoms, other adverse events), developmental measures (adaptive behavior, intelligence quotient [IQ]), and standardized rating instruments. Treatment over the follow-up period, after completion of protocol participation, was uncontrolled. Statistical analyses assessed outcome over time with or without prolonged risperidone therapy. Two-thirds of the 84 subjects continued to receive risperidone (mean 2.47 mg/day, S.D. 1.29 mg). At follow-up, risperidone was associated with more enuresis, more excessive appetite, and more weight gain, but not more adverse neurological effects. No clinically significant events were noted on blood counts, chemistries, urinalysis, ECG, or interim medical history. Regardless of drug condition at follow-up, there was considerable improvement in maladaptive behavior compared with baseline, including core symptoms associated with autism. Height and weight gains were elevated with risperidone. Social skills on Vineland Adaptive Behavior Scale (VABS) improved with risperidone. Parent-rated Aberrant Behavior Checklist (ABC) Irritability subscale scores were reduced in those taking risperidone at follow

  1. Effects of shock waves on the microcirculation in critical limb ischemia (CLI) (8-week study).

    Science.gov (United States)

    De Sanctis, M T; Belcaro, G; Nicolaides, A N; Cesarone, M R; Incandela, L; Marlinghaus, E; Griffin, M; Capodanno, S; Ciccarelli, R

    2000-08-01

    Shock waves (SWs) are used to control and decrease pain in several clinical conditions (e.g., painful elbow and shoulder, etc). This clinical effect may be due to cellular stunning of the tissues (particularly nervous components) in the area treated with SW. It may also be the consequence of unknown metabolic actions on tissues, which may include changes in cellular permeability and the liberation of proteins and mediators locally acting on pain and nerve endings. The aim of this study was to evaluate the reduction in pain and the microcirculation improvement induced by SWs treatment in an 8-week study in patients with chronic limb ischemia (CLI). Patients with CLI (15 with rest pain only and 15 with rest pain and limited distal necrosis) were included. The treatment was based on a 30-minute SWs session, three times weekly for 2 weeks. Clinical and microcirculatory evaluation were performed with laser Doppler Po2 and Pco2 measurements. Pain was measured with an analogue scale line. A Minilith SL1 (Storz Medical, Switzerland) litotriptor was used. The parabolic reflector is coupled to the skin with a silicon water cushion. Focal pressure was adjusted between 6 and 70 Mpa in eight steps. The energy flux density was variable from 0.03 to 0.5 mJ/mm2. Focal diameter and distance were defined (depth of target within the patient's foot of about 70 mm). The coded intensity used in this study was between 6 and 8 and the application time was 20 min (at four impulses per second). Twenty-eight of the 30 patients with CLI (15 with rest pain only and 13 with necrosis) completed the study. The treatment was well tolerated. Blood pressure was unchanged after 8 weeks while the increase in laser Doppler flux was significant (p<0.05) (at all measurements after treatment). The ORACLE score at 1 and 8 weeks was decreased (p<0.05). The same trend was observed with the analogue scale line for pain (p<0.05). PO2 increased (p<0.05) and Pco2 decreased (p<0.05). Tibial pressure did not

  2. Self-reported symptoms 8weeks after discharge: A comparison of takotsubo syndrome and myocardial infarction.

    Science.gov (United States)

    Wallström, Sara; Ulin, Kerstin; Omerovic, Elmir; Ekman, Inger

    2016-12-01

    Takotsubo syndrome is a form of acute, reversible heart failure that has gained increasing attention. It affects mostly postmenopausal women, and its acute onset and symptoms mimic acute myocardial infarction. The distinct feature of takotsubo syndrome is the ballooning of a ventricle, but the complete pathophysiological mechanisms are not fully understood. Both short-term and long-term survival are affected, but little is known about the illness experience and self-reported residual symptoms after discharge from hospital. To measure and compare self-reported residual symptoms between patients with takotsubo syndrome and those with acute myocardial infarction. Questionnaire data measuring self-reported symptoms were collected from 48 patients with takotsubo syndrome and 79 patients with acute myocardial infarction 8weeks after discharge. A multivariate adjusted complete case regression model was used to compare the frequency and severity of symptoms. Self-reported symptoms 8weeks after discharge differed little between patients with takotsubo syndrome and those with acute myocardial infarction. Both groups reported symptoms, including pain, fatigue, breathlessness, and sleep disturbance. At onset there were significant differences between the groups concerning previous diabetes mellitus, cardiac troponin T, ejection fraction and Killip class. There were no significant between-group differences in frequency or severity of symptoms after adjusting for these differences. Patients with takotsubo syndrome experience residual symptoms after discharge. Symptoms in several cardiovascular diseases predict quality of life, re-admission, and mortality. Symptom management should be integrated into follow-up care for patients with takotsubo syndrome. One way of achieving this is through person-centered care. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. Beneficial Effects of an 8-Week, Very Low Carbohydrate Diet Intervention on Obese Subjects

    Science.gov (United States)

    Gu, Yunjuan; Yu, Haoyong; Li, Yuehua; Ma, Xiaojing; Lu, Junxi; Yu, Weihui; Xiao, Yunfeng; Bao, Yuqian; Jia, Weiping

    2013-01-01

    Aim. To investigate the effects of weight loss during an 8-week very low carbohydrate diet (VLCD) on improvement of metabolic parameters, adipose distribution and body composition, and insulin resistance and sensitivity in Chinese obese subjects. Methods. Fifty-three healthy obese volunteers were given an 8-week VLCD. The outcomes were changes in anthropometry, body composition, metabolic profile, abdominal fat distribution, liver fat percent (LFP), and insulin resistance and sensitivity. Results. A total of 46 (86.8%) obese subjects completed the study. The VLCD caused a weight loss of −8.7 ± 0.6 kg (mean ± standard error (SE), P < 0.0001) combined with a significant improvement of metabolic profile. In both male and female, nonesterified fatty acid (NEFA) significantly decreased (−166.2 ± 47.6 μmol/L, P = 0.001) and β-hydroxybutyric acid (BHA) increased (0.15 ± 0.06 mmol/L, P = 0.004) after eight weeks of VLCD intervention. The significant reductions in subcutaneous fat area (SFA), visceral fat area (VFA), and LFP were −66.5 ± 7.9 cm2, −35.3 ± 3.9 cm2, and −16.4 ± 2.4%, respectively (all P values P < 0.0001). HOMA IR and HOMA β significantly decreased while whole body insulin sensitivity index (WBISI) increased (all P values P < 0.001). Conclusion. Eight weeks of VLCD was an effective intervention in obese subjects. These beneficial effects may be associated with enhanced hepatic and whole-body lipolysis and oxidation. PMID:23573151

  4. Beneficial Effects of an 8-Week, Very Low Carbohydrate Diet Intervention on Obese Subjects

    Directory of Open Access Journals (Sweden)

    Yunjuan Gu

    2013-01-01

    Full Text Available Aim. To investigate the effects of weight loss during an 8-week very low carbohydrate diet (VLCD on improvement of metabolic parameters, adipose distribution and body composition, and insulin resistance and sensitivity in Chinese obese subjects. Methods. Fifty-three healthy obese volunteers were given an 8-week VLCD. The outcomes were changes in anthropometry, body composition, metabolic profile, abdominal fat distribution, liver fat percent (LFP, and insulin resistance and sensitivity. Results. A total of 46 (86.8% obese subjects completed the study. The VLCD caused a weight loss of −8.7±0.6 kg (mean ± standard error (SE, P<0.0001 combined with a significant improvement of metabolic profile. In both male and female, nonesterified fatty acid (NEFA significantly decreased (−166.2±47.6 μmol/L, P=0.001 and β-hydroxybutyric acid (BHA increased (0.15±0.06 mmol/L, P=0.004 after eight weeks of VLCD intervention. The significant reductions in subcutaneous fat area (SFA, visceral fat area (VFA, and LFP were −66.5±7.9 cm2, −35.3±3.9 cm2, and −16.4±2.4%, respectively (all P values P<0.0001. HOMA IR and HOMA β significantly decreased while whole body insulin sensitivity index (WBISI increased (all P values P<0.001. Conclusion. Eight weeks of VLCD was an effective intervention in obese subjects. These beneficial effects may be associated with enhanced hepatic and whole-body lipolysis and oxidation.

  5. Effects of an 8-week meditation program on the implicit and explicit attitudes toward religious/spiritual self-representations.

    Science.gov (United States)

    Crescentini, Cristiano; Urgesi, Cosimo; Campanella, Fabio; Eleopra, Roberto; Fabbro, Franco

    2014-11-01

    Explicit self-representations often conflict with implicit and intuitive self-representations, with such discrepancies being seen as a source of psychological tension. Most of previous research on the psychological effects of mindfulness-meditation has assessed people's self-attitudes at an explicit level, leaving unknown whether mindfulness-meditation promotes changes on implicit self-representations. Here, we assessed the changes in implicit and explicit self-related religious/spiritual (RS) representations in healthy participants following an 8-week mindfulness-oriented meditation (MOM) program. Before and after meditation, participants were administered implicit (implicit association test) and explicit (self-reported questionnaires) RS measures. Relative to control condition, MOM led to increases of implicit RS in individuals whit low pre-existing implicit RS and to more widespread increases in explicit RS. On the assumption that MOM practice may enhance the clarity of one's transcendental thoughts and feelings, we argued that MOM allows people to transform their intuitive feelings of implicit RS as well as their explicit RS attitudes.

  6. Safety evaluation of orally administered afoxolaner in 8-week-old dogs.

    Science.gov (United States)

    Drag, Marlene; Saik, Judith; Harriman, Jay; Larsen, Diane

    2014-04-02

    The safety profile of afoxolaner, a new isoxazoline molecule, was evaluated following the regulatory requirements when administered six times orally in a soft chewable formulation at a dose of at least 1×, 3× or 5× the maximum exposure dose (6.3mg/kg) in 8-week-old Beagle dogs. Thirty-two healthy puppies (16 males and 16 females) were enrolled and allocated randomly to one of four treatment groups. Treatments were administered at three, one-month dose intervals (Days 0, 28 and 56) followed by three, 2-week dose intervals (Days 84, 98 and 112). The study ended at Day 126. The groups were: Group 1: non-treated control; Group 2: afoxolaner chews administered at a dosage of at least 6.3mg/kg (1×); Group 3: afoxolaner chews administered at a dosage of at least 18.9 mg/kg (3×); and Group 4: afoxolaner chews administered at a dosage of at least 31.5mg/kg (5×). All dogs were examined for general health twice a day beginning on at least Day-14. Physical examinations, and blood collections for clinical pathology analysis and afoxolaner plasma concentrations, were performed throughout the study. On Day 126, 2 weeks following the last treatment, all dogs were humanely euthanized prior to the conduction of a full necropsy with tissue collection. No afoxolaner-related changes were observed in growth, physical variables, clinical pathology variables, or tissues examined histologically. No clinically or statistically significant health abnormalities related to the administration of afoxolaner were observed. Vomiting and diarrhea were observed sporadically across all groups including the controls. The kinetics of afoxolaner plasma concentrations was linear following 6 doses of 6.3, 18.9 and 31.5mg/kg and dose proportionality was demonstrated. There were no statistical differences (pafoxolaner was shown to be safe when administered repeatedly in a soft chewable formulation at up to 5× the maximum exposure dose in dogs as young as 8 weeks of age.

  7. Effects of 8-week swimming training on carotid arterial stiffness and hemodynamics in young overweight adults.

    Science.gov (United States)

    Yuan, Wen-Xue; Liu, Hai-Bin; Gao, Feng-Shan; Wang, Yan-Xia; Qin, Kai-Rong

    2016-12-28

    Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-based exercise modalities may not be suitable for overweight individuals, in terms of risks of joint injury. The purpose of this study was to determine the effects of 8-week swimming training and 4-week detraining on carotid arterial stiffness and hemodynamics in young overweight adults. Twenty young male adults who were overweight were recruited and engaged in 8-week of swimming training and 4-week detraining. Five individuals withdrew due to lack of interest and failure to follow the training protocol. Body Fat Percentage (BFP) and carotid hemodynamic variables were measured on a resting day at the following intervals: baseline, 4 weeks, 8 weeks after swimming training and 4 weeks after detraining. A repeated analysis of variance (ANOVA) was used to assess the differences between baseline and each measurement. When significant differences were detected, Tukey's test for post hoc comparisons was used. Eight-week swimming training at moderate intensity decreased BFP, including the trunk and four extremities. Additionally, the BFP of the right and left lower extremities continued to decrease in these overweight adults 4 weeks after ceasing training. Carotid arterial stiffness decreased, while there were no significant changes in arterial diameters. Blood flow velocity, flow rate, maximal and mean wall shear stress increased, while systolic blood pressure and peripheral resistance decreased. No significant differences existed in minimal wall shear stress and oscillatory shear stress. Eight-week swimming training at moderate intensity exhibited beneficial effects on systolic blood pressure, arterial stiffness and blood supply to the brain in overweight adults. Moreover, maximal and mean wall shear stress increased after training. It is worth noting that these

  8. Effect of 8 Weeks of High Intensity Interval Training on Plasma Levels of Adiponectin and Leptin in Overweight Nurses

    Directory of Open Access Journals (Sweden)

    Sahar Avazpor

    2016-07-01

    Full Text Available Background: High intensity interval training (HIIT is a novel training method which has received most attention in recent years. The aim of this study was to examine the effect of 8 weeks of high intensity interval training (HIIT on plasma levels of adiponectin and leptin in overweight nurses.Materials and Methods: 27 nurses (mean age 25.81±60 years, height 158.01±67 cm and weight 69.41±25 kg were voluntarily selected and randomly assigned to three groups (each group 9 subjects: 1. HIIT (type 1 including 8 seconds of sprint running and 12 seconds of active recovery 2. HIIT (type 2 including 40-m shuttle run with maximum speed 3. Control group. HIIT (type 1 was performed for eight weeks, three sessions per week, each session 6-9 min. With more than 90% HRmax. HIIT (type 2 was applied for eight weeks, three sessions per week with more than 90% HRmax. The control group did not participate in any training protocol.Results: The data were analyzed by the dependent t test and ANOVA. The results showed that the HIIT (type 1 and (type 2 had significant effects on plasma leptin decrease and plasma adiponectin concentration increase in nurses. One-way analysis of variance (ANOVA was used to analyze the intergroup data at p˂0.05.Conclusion: The results showed a significant difference in the variables (leptin and adiponectin among HIIT (type 1, HIIT (type 2 and control.

  9. Effects of 8 Weeks Aerobic Training on the Social-Physical Anxiety in Women with Multiple Sclerosis

    Directory of Open Access Journals (Sweden)

    Forough Rahmati

    2014-07-01

    Full Text Available Nowadays, ailments which are known as specific diseases make the society we live in suffer, and scientific researches pay much attention to the effect of sport and physical activity on these diseases and introduce sports as treatment for them. The purpose of this study was to check the effect of an aerobic training course on social-physical anxiety in women with Multiple Sclerosis (MS. The study population consisted of all inactive women reported by MS community of Tehran in 2012. Of them, 24 ones have been chosen at random (age 32±11 years old and selected in two groups of control and experimental at random. The social-physical anxiety scale (SPAS was used to measure the social-physical anxiety in these patients. The findings indicated a noticeable decrease in the amount of social-physical anxiety in women with MS after 8 weeks of aerobic training (P<0.001. Eventually, we can conclude that aerobic training are effective on decreasing the social-physical anxiety of patients suffering from MS, and it can, by its nature, decrease the social-physical anxiety in these people and promote health and participation in sports activities.

  10. Psychopharmacotherapy of panic disorder: 8-week randomized trial with clonazepam and paroxetine

    Directory of Open Access Journals (Sweden)

    A.E. Nardi

    2011-04-01

    Full Text Available The objective of the present randomized, open-label, naturalistic 8-week study was to compare the efficacy and safety of treatment with clonazepam (N = 63 and paroxetine (N = 57 in patients with panic disorder with or without agoraphobia. Efficacy assessment included number of panic attacks and clinician ratings of the global severity of panic disorders with the clinical global impression (CGI improvement (CGI-I and CGI severity (CGI-S scales. Most patients were females (69.8 and 68.4% in the clonazepam and paroxetine groups, respectively and age (mean ± SD was 35.9 ± 9.6 years for the clonazepam group and 33.7 ± 8.8 years for the paroxetine group. Treatment with clonazepam versus paroxetine resulted in fewer weekly panic attacks at week 4 (0.1 vs 0.5, respectively; P < 0.01, and greater clinical improvements at week 8 (CGI-I: 1.6 vs 2.9; P = 0.04. Anxiety severity was significantly reduced with clonazepam versus paroxetine at weeks 1 and 2, with no difference in panic disorder severity. Patients treated with clonazepam had fewer adverse events than patients treated with paroxetine (73 vs 95%; P = 0.001. The most common adverse events were drowsiness/fatigue (57%, memory/concentration difficulties (24%, and sexual dysfunction (11% in the clonazepam group and drowsiness/fatigue (81%, sexual dysfunction (70%, and nausea/vomiting (61% in the paroxetine group. This naturalistic study confirms the efficacy and tolerability of clonazepam and paroxetine in the acute treatment of patients with panic disorder.

  11. The Effects of 8-week Nigella sativa Supplementation and Aerobic Training on Lipid Profile and VO2 max in Sedentary Overweight Females.

    Science.gov (United States)

    Farzaneh, Esmail; Nia, Farhad Rahmani; Mehrtash, Mohammad; Mirmoeini, Fatemeh Sadat; Jalilvand, Mohammad

    2014-02-01

    Regular moderate intensity physical activity and lipid lowering effects of Nigella sativa (N. sativa) supplementation may be appropriate management for sedentary overweight females. Therefore, the aim of the present study was to examine the effects of long-term N. sativa supplementation and aerobic training on lipid profile and maximal oxygen consumption (VO2 max) in sedentary overweight females. In this randomized, double-blind, controlled trial, which was conducted in Kerman city (Iran), 20 sedentary overweight females were divided into two groups and assigned to N. sativa supplementation (N. sativa capsules) or a placebo for the 8 weeks, both groups participated in an aerobic training program (3 times/week). Each N. sativa capsule contained 500 ± 10 mg N. sativa crushed seeds and subjects had to take 2 g N. sativa per day for 8 weeks. Blood lipids and VO2 max were determined at baseline and at the end of 8 weeks. N. sativa supplementation lowered total cholesterol (TC) (P high density lipoprotein (HDL) and VO2 max (P training program lowered TC (P training program and N. sativa supplementation lowered LDL and HDL (P training plus N. sativa supplementation have a synergistic effect in improve profile lipid parameters.

  12. Effect of 8 weeks of pre-season training on body composition, physical fitness, anaerobic capacity, and isokinetic muscle strength in male and female collegiate taekwondo athletes.

    Science.gov (United States)

    Seo, Myong-Won; Jung, Hyun-Chul; Song, Jong-Kook; Kim, Hyun-Bae

    2015-04-01

    The purpose of the study was to determine the effect of 8 weeks pre-season training on body composition, physical fitness, anaerobic capacity, and isokinetic strength in collegiate taekwondo athletes. Thirty-four collegiate athletes (male: 22, female: 12) participated. Body composition, bone mineral density, physical fitness, anaerobic capacity, and isokinetic muscle strength were tested. After statistical analysis was performed the results indicated that there were significant decreases in body weight, percent body fat, and fat tissue after 8 weeks of pre-season training. Bone mineral density increased significantly only in males. There were significant improvements in the 50 m shuttle run and 20 m multistage endurance run in both males and females. The sit & reach test and standing long jump were not significantly changed after 8 weeks. Relative peak power and anaerobic capacity were significantly improved in males. Significant increases in angular velocity were observed for knee extension at both % BW 60°/sec and 180°/sec in both males and females. A significant increase in angular velocity was seen for right knee flexion at % BW 60°/sec for males, but it decreased at % BW 180°/sec for both males and females. In conclusion, this study suggests that 8 weeks of pre-season training has a positive effect on body composition, physical fitness, anaerobic capacity, isokinetic muscular strength, and endurance. Nevertheless, an exercise approach with the goal of increasing lean tissue, and improving power in knee flexors and flexibility of athletes, should be included in the training program.

  13. An 8-week interdisciplinary learning module, which focuses on innovation and entrepreneurship

    DEFF Research Database (Denmark)

    Sørensen, Brigitte; Andersen, Helle Tvorup; Duus, Lene;

    2015-01-01

    where we want to share our knowledge of learning method and to discuss the academic content and the teaching method. Participants The target audience is anyone interested in the development of teaching methods and interdisci-plinary collaboration in health care. Method The workshop consists of three...... elements: Theoretical presentations, innovative workshop, collect-ing. The workshop participants will be actively involved in practical learning methods. Expected outcomes For participant and presenter is the outcomes expected to be increased knowledge about innova-tive teaching methods and forms...

  14. PUBLICATION OF SCIENTIFIC PERIODICALS AT UNIVERSITIES:NEW CHALLENGES, PARTICIPANTS TECHNOLOGY

    Directory of Open Access Journals (Sweden)

    T. О. Kolesnykova

    2015-11-01

    Full Text Available Purpose. Publication of scientific periodicals in the Universities is very important and necessary element in the infrastructure of scientific communication. The aim of the article is: 1 providing a new model of publication system of the University scientific periodicals (on the example of Dnipropetrovsk National University of Railway Transport named after Academician V. Lazaryan – DNURT; 2 studying the peculiarities of the «Library publishing» model (Library Publishing and library as a new participant in the publication of world scientific periodicals of the University; 3 description of the developed software automation typesetting of scientific articles and their integration into international databases of scientific and technical information. Methodology. The scientists investigated: 1 the system of publication of scientific periodicals at DNURT; 2 integration system of electronic versions of periodicals and individual articles of scientists from DNURT into the world scientific databases; 3 publishing activity of the scientific and technical library of the University. Findings. The authors proved the need for the fast updates in each higher education institution of Ukrainian management system of scientific periodicals and the creation of the periodicals development concept. The conditions for the occurrence of positive changes in the publishing process in Universities were determined and named as a new participant in these processes – University library. The list of new tasks inherent in the scientific periodicals of the Universities was presented. The software product «Digital designer» was created as a new applied information technology solution to extend the functionality of the basic system information of the publication according to its editorial policy. Originality. The scientists studied the transformation process of the organizational structure of scientific periodicals publishing in the Universities of Ukraine and the world

  15. The effects of honey supplementation on seminal plasma cytokines, oxidative stress biomarkers, and antioxidants during 8 weeks of intensive cycling training.

    Science.gov (United States)

    Tartibian, Bakhtyar; Maleki, Behzad Hajizadeh

    2012-01-01

    The purpose of this study was to examine the effects of natural honey supplementation on seminal plasma cytokines, oxidative stress biomarkers, and antioxidants during 8 weeks of intensive cycling training in male road cyclists. Thirty-nine healthy nonprofessional male road cyclists aged 18-28 years participated in this study. The participants were randomly assigned to exercise + supplement (E + S, n = 20) and exercise (E, n = 19) groups. All subjects participated in 8 weeks of intensive cycling training. Ninety minutes before each training session, subjects in the E + S group supplemented with 70 g of honey, whereas subjects in the E group received 70 g of an artificial sweetener. All subjects had an initial semen sampling at baseline (T(1)). The next 6 semen collections were collected immediately (T(2)) and 12 (T(3)) and 24 hours (T(4)) after the last training session in week 4, as well as immediately (T(5)) and 12 (T(6)) and 24 hours (T(7)) after the last training session in week 8, respectively. In the E group, 8 weeks of intensive cycling training significantly increased seminal interleukin (IL)-1β, IL-6, IL-8, tumor necrosis factor (TNF)-α, reactive oxygen species (ROS), and malondialdehyde (MDA) levels (P < .008) and significantly decreased the levels of seminal superoxide dismutase (SOD), catalase, and total antioxidant capacity (TAC) (P < .008). Significantly less elevation in seminal IL-1β, IL-6, IL-8, TNF-α, ROS, and MDA levels (P < .008) and significant increases in seminal SOD, catalase, and TAC concentrations were observed after the honey supplementation in the E + S group (P < .008). It may be possible that honey supplementation following long-term intensive cycling training would be effective in attenuating the probable aggravating effects of intensive cycling training on spermatogenesis and fertility capacity in road cyclists.

  16. An 8-week brain MRI follow-up analysis of rat eosinophilic meningitis caused by Angiostrongylus cantonensis infection.

    Science.gov (United States)

    Shyu, L Y; Tsai, H H; Lin, D P; Chang, H H; Tyan, Y S; Weng, J C

    2014-09-01

    Early differential diagnosis and timely follow-up are advantageous in the management of Angiostrongylus cantonensis infection. This study aimed to characterize angiostrongyliasis in the rat brain for an 8-week period using magnetic resonance imaging (MRI) with contrast-enhanced T1-weighted images (T1WI), T2-weighted imaging (T2WI), fluid attenuation inversion recovery (FLAIR) and R2 mapping sequences. The data were analysed with Mathematica and Matlab software programs for weekly changes in each brain following the infection of 20, 50, 100 and 300 third-stage larvae (L3), respectively. The results showed that the average subarachnoid space detected by T2WI technique was peaked up to 10% increase of original size on day 35 after 100 or 300 larvae infection, while those infected with 20 or 50 larvae showed less than 4% increase during the entire course of observation. This increase was relevant to the mortality of the infected rats, because those with 100 or 300 larvae infections showed a sharp decrease in survival rate before day 40. After day 40, the average subarachnoid space was decreased, but the average ventricle size was persistently increased, with the highest increase observed in the group infected with 300 larvae on day 56. Furthermore, the R2 mapping mean and R2 mapping size were significantly different between the brains with severe infection (100 and 300 larvae groups together) and those with mild infection (20 and 50 larvae groups together) on day 49, but not on day 35. Our results showed that diagnosis for different quantity of larvae infection using MRI is possible and follow-up characterization is informative in revealing the effects of angiostrongyliasis on different brain areas. In conclusion, our results support the use of MRI as a non-invasive diagnostic technique for eosinophilic meningitis caused by A. cantonensis infection.

  17. Atomoxetine treatment may decrease striatal dopaminergic transporter availability after 8 weeks: pilot SPECT report of three cases

    Science.gov (United States)

    Akay, Aynur Pekcanlar; Kaya, Gamze Capa; Baykara, Burak; Demir, Yusuf; Özek, Handan; Alsen, Sevay; Eren, Mine Sencan; Emiroglu, Neslihan Inal; Ertay, Turkan; Ozturk, Yesim; Miral, Suha; Durak, Hatice; Tufan, Evren

    2015-01-01

    Attention deficit/hyperactivity disorder is one of the most common neurodevelopmental disorders. The pathophysiology is thought to involve noradrenaline and dopamine. The role of dopamine transporter (DAT) was evaluated in imaging studies using mostly dopamine reuptake inhibitors. Atomoxetine is a selective noradrenaline reuptake inhibitor. Here we report the results of a pilot study conducted to evaluate changes in striatal DAT after 8 weeks of atomoxetine treatment. Our results suggest that 8 weeks of atomoxetine treatment may change striatal DAT bioavailability as measured via SPECT but that change was not correlated with genotype or clinical improvement. PMID:26640376

  18. Frontal-subcortical volumetric deficits in single episode, medication-naive depressed patients and the effects of 8 weeks fluoxetine treatment: a VBM-DARTEL study.

    Directory of Open Access Journals (Sweden)

    Lingtao Kong

    Full Text Available BACKGROUND: Convergent studies suggest that morphological abnormalities of frontal-subcortical circuits which involved with emotional and cognitive processing may contribute to the pathophysiology of major depressive disorder (MDD. Antidepressant treatment which has been reported to reverse the functional abnormalities of frontal-subcortical circuits in MDD may have treating effects to related brain morphological abnormalities. In this study, we used voxel-based morphometry method to investigate whole brain structural abnormalities in single episode, medication-naïve MDD patients. Furthermore, we investigated the effects of an 8 weeks pharmacotherapy with fluoxetine. METHODS: 28 single episode, medication-naïve MDD participants and 28 healthy controls (HC acquired the baseline high-resolution structural magnetic resonance imaging (sMRI scan. 24 MDD participants acquired a follow-up sMRI scan after 8 weeks antidepressant treatment. Gray matter volumetric (GMV difference between groups was examined. RESULTS: Medication-naïve MDD had significantly decreased GMV in the right dorsolateral prefrontal cortex and left middle frontal gyrus as well as increased GMV in the left thalamus and right insula compared to HC (P<0.05, corrected. Moreover, treated MDD had significantly increased GMV in the left middle frontal gyrus and right orbitofrontal cortex compared to HC (P<0.05, corrected. No difference on GMV was detected between medication-naïve MDD group and treated MDD group. CONCLUSIONS: This study of single episode, medication-naïve MDD subjects demonstrated structural abnormalities of frontal-subcortical circuitsin the early stage of MDD and the effects of 8 weeks successful antidepressant treatment, suggesting these abnormalities may play an important role in the neuropathophysiology of MDD at its onset.

  19. Effects of 8-week Pilates exercise program on menopausal symptoms and lumbar strength and flexibility in postmenopausal women.

    Science.gov (United States)

    Lee, Haelim; Caguicla, Joy Matthew Cuasay; Park, Sangseo; Kwak, Dong Jick; Won, Deuk-Yeon; Park, Yunjin; Kim, Jeeyoun; Kim, Myungki

    2016-06-01

    The aim of this study was to investigate the effects of an 8-week Pilates exercise program on menopausal symptoms and lumbar strength and flexibility in postmenopausal women. In total, 74 postmenopausal women were recruited and randomly allocated to a Pilates exercise group (n=45) and a control group (n=29). Menopausal symptoms were measured through a questionnaire, while lumbar strength was measured through a lumbar extension machine, and lumbar flexibility was measured through sit-and-reach and trunk lift tests performed before and after the Pilates exercise program, respectively. The Pilates exercises consisted of 7-10 min for warm-up, 35-40 min for the main program modified from Pilates Academy International, and 5-7 min for the cool-down, and were performed 3 times a week for 8 weeks. The results showed a significant decrease in menopausal symptoms except urogenital symptoms. Also, the results presented a significant increase in lumbar strength and flexibility after 8 weeks of the Pilates exercise program. We concluded that an 8-week Pilates exercise program is effective in decreasing menopausal symptoms and increasing lumbar strength and flexibility.

  20. Concurrent Training in Prepubescent Children: The Effects of 8 Weeks of Strength and Aerobic Training on Explosive Strength and V[Combining Dot Above]O2max.

    Science.gov (United States)

    Alves, Ana R; Marta, Carlos C; Neiva, Henrique P; Izquierdo, Mikel; Marques, Mário C

    2016-07-01

    Alves, AR, Marta, CC, Neiva, HP, Izquierdo, M, and Marques, MC. Concurrent training in prepubescent children: the effects of 8 weeks of strength and aerobic training on explosive strength and V[Combining Dot Above]O2max. J Strength Cond Res 30(7): 2019-2032, 2016-The purpose of this study was to compare the effects of 8-week training periods of strength training alone (GS), combined strength and aerobic training in the same session (GCOM1), or in 2 different sessions (GCOM2) on explosive strength and maximal oxygen uptake (V[Combining Dot Above]O2max) in prepubescent children. Of note, 168 healthy children, aged 10-11 years (10.9 ± 0.5), were randomly selected and assigned to 3 training groups to train twice a week for 8 weeks: GS (n = 41), GCOM1 (n = 45), GCOM2 (n = 38) groups, and a control group (GC) (n = 44; no training program). The GC maintained the baseline level, and trained-induced differences were found in the experimental groups. Differences were observed in the 1 and 3-kg medicine ball throws (GS: +5.8 and +8.1%, respectively; GCOM1: +5.7 and +8.7%, respectively; GCOM2: +6.2 and +8%, respectively, p training period induced gains in the 20-m time (GS: +2.1%; GCOM1: +2.1%; GCOM2: +2.3%, p strength, and explosive strength from pretraining to posttraining. The higher gains were observed for concurrent training when it was performed in different sessions. These results suggest that concurrent training in 2 different sessions seems to be an effective and useful method for training-induced explosive strength and V[Combining Dot Above]O2max in prepubescent children. This could be considered as an alternative way to optimize explosive strength training and cardiorespiratory fitness in school-based programs.

  1. Growth rate, health and welfare in a dairy herd with natural suckling until 6–8 weeks of age: a case report

    Directory of Open Access Journals (Sweden)

    Mejdell Cecilie

    2007-06-01

    Full Text Available Abstract Over a period of two years, growth rate and health were measured for dairy calves allowed to suckle their mothers up to 6–8 weeks of age. Thirty-one calves were weighted weekly, and the mean daily growth rate was 1.2 ± 0.03 kg from birth up to 13 weeks of age. Illness in calves and young stock was not observed. In the cows, the mean incidences of ketosis, displaced abomasum, puerperal paresis, mastitis, teat injury and retained placenta were 0, 0, 8, 22, 1 and 1%, respectively, during a 6-year period. The mean daily gain of 56 growing bulls was 1.4 kg when slaughtered at 15 months of age, which is higher than the mean daily gain of 0.95 kg in the population. Probiotics, hormones and vaccines were not used, and antibiotics were only used for treating illness. The present study indicates many advantages and few problems when dairy calves are penned together with the cows and allowed natural feeding up to 6–8 weeks of age. This production system was easy to manage, preferred by the farmer, and may satisfy the public concern regarding the practice of immediate separation of cow and calf in commercial milk production.

  2. Learning by doing-teaching systematic review methods in 8 weeks.

    Science.gov (United States)

    Li, Tianjing; Saldanha, Ian J; Vedula, S Swaroop; Yu, Tsung; Rosman, Lori; Twose, Claire; N Goodman, Steven; Dickersin, Kay

    2014-09-01

    The objective of this paper is to describe the course "Systematic Reviews and Meta-analysis" at the Johns Hopkins Bloomberg School of Public Health. A distinct feature of our course is a group project in which students, assigned to multi-disciplinary groups, conduct a systematic review. In-class sessions comprise didactic lectures, hands-on exercises, demonstrations, discussion, and group work. Students also work outside of class to complete the systematic review. Students evaluated the course at the end of the term. We also surveyed students from 2004 to 2012 to learn more about the long-term impact of the course. The course has been offered to more than 800 students since 1995. In our view, aspects that worked well include the hands-on approach, students working in a multidisciplinary group, intensive interaction with the teaching team, moving to an online approach, and continuous updates of the course content. A persistent issue is the constraint of time. 193 of 211 (91%) survey participants reported that the course is currently useful or as having an impact on their work. Our experiences have led us to remain committed to a hands-on approach. Our course serves as a bridge between classroom learning and real-world practice, and provides an example of teaching systematic review. Copyright © 2014 John Wiley & Sons, Ltd.

  3. Participation

    African Journals Online (AJOL)

    chifaou.amzat

    2011-08-02

    Aug 2, 2011 ... there is still little theorising about those on the other side of the policy equation. ... The concept of participation designates human beings – their priorities, knowledge .... Thus, a person's mode of participation in the enterprise.

  4. [Influence of an 8-week exercise intervention on body composition, physical fitness, and mental health in female nursing students].

    Science.gov (United States)

    Yamazaki, Fumio; Yamada, Hisao; Morikawa, Sachiko

    2013-03-01

    To determine the effectiveness of habitual exercise on the health promotion of college students, we measured the body composition and physical fitness of female nursing students before (Pre) and after (Post) an 8-week low-intensity exercise intervention. We also conducted a questionnaire survey of their mental health condition before and at every 4 weeks during the intervention. The quantity of physical exercise increased (P exercise intervention did not alter the body weight, but decreased the body fat (Pre, 26.8 ± 0.5%; Post, 24.9 ± 0.5%, P mental health were significantly raised by the intervention. These results suggest that habitual exercise for 8 weeks was effective for the promotion of physical and mental health in female nursing students.

  5. The Effects of 8-Weeks Aerobic Exercise Program on Blood Lipids and Cholesterol Profile of Smokers vs. Non Smokers

    Science.gov (United States)

    Taifour, Akef; AL-Shishani, Ahmad; Khasawneh, Aman; AL-Nawaiseh, Ali; Bakeer, Mohammed

    2015-01-01

    The aim of this study was to compare the effects of 8-week aerobic exercise program on blood lipids and cholesterol profile of smoker's vs. non-smokers. A total of 34 male subjects (18 non-smokers and 16 smokers) took part in this study. Both groups were pre- and post tested in their blood-lipids and cholesterol profile before and after the 8-week…

  6. Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers

    Directory of Open Access Journals (Sweden)

    Jintanaporn Wattanathorn

    2012-01-01

    Full Text Available Health-related physical fitness declines as the age advances. Oxidative stress is reported to contribute the crucial role on this phenomenon. This condition is also enhanced by antioxidant. Therefore, we aimed to determine the effect of Kaempferia parviflora, a plant reputed for antifatigue, longevity promotion, and antioxidant effects, on health-related quality physical fitness and oxidative status of the healthy elderly volunteers. Total 45 subjects had been randomized to receive placebo or K. parviflora extract at doses of 25 or 90 mg once daily for 8 weeks. They were determined baseline data of physical performance using 30 sec chair stand test, hand grip test, 6 min walk test, and tandem test. Serum oxidative stress markers including malondialdehde (MDA level and the activities of superoxide dismutase (SOD, catalase (CAT, and glutathione peroxidase (GSH-Px were also assayed. All assessments were performed every 4 weeks throughout the 8-week study period. The results showed that K. parviflora increased performance in 30-second chair stand test and 6 min walk test together with the increased all scavenger enzymes activities and the decreased MDA level. Therefore, K. parviflora can enhance physical fitness partly via the decreased oxidative stress. In conclusion, K. parviflora is the potential health supplement for elderly. However, further study is required.

  7. Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers.

    Science.gov (United States)

    Wattanathorn, Jintanaporn; Muchimapura, Supaporn; Tong-Un, Terdthai; Saenghong, Narisara; Thukhum-Mee, Wipawee; Sripanidkulchai, Bungorn

    2012-01-01

    Health-related physical fitness declines as the age advances. Oxidative stress is reported to contribute the crucial role on this phenomenon. This condition is also enhanced by antioxidant. Therefore, we aimed to determine the effect of Kaempferia parviflora, a plant reputed for antifatigue, longevity promotion, and antioxidant effects, on health-related quality physical fitness and oxidative status of the healthy elderly volunteers. Total 45 subjects had been randomized to receive placebo or K. parviflora extract at doses of 25 or 90 mg once daily for 8 weeks. They were determined baseline data of physical performance using 30 sec chair stand test, hand grip test, 6 min walk test, and tandem test. Serum oxidative stress markers including malondialdehde (MDA) level and the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) were also assayed. All assessments were performed every 4 weeks throughout the 8-week study period. The results showed that K. parviflora increased performance in 30-second chair stand test and 6 min walk test together with the increased all scavenger enzymes activities and the decreased MDA level. Therefore, K. parviflora can enhance physical fitness partly via the decreased oxidative stress. In conclusion, K. parviflora is the potential health supplement for elderly. However, further study is required.

  8. Effect of 8 Weeks of High Intensity Interval Training on Plasma Levels of Adiponectin and Leptin in Overweight Nurses

    OpenAIRE

    Sahar Avazpor; Jamal Fazel Kalkhoran; Hojat Allah Amini

    2016-01-01

    Background: High intensity interval training (HIIT) is a novel training method which has received most attention in recent years. The aim of this study was to examine the effect of 8 weeks of high intensity interval training (HIIT) on plasma levels of adiponectin and leptin in overweight nurses.Materials and Methods: 27 nurses (mean age 25.81±60 years, height 158.01±67 cm and weight 69.41±25 kg) were voluntarily selected and randomly assigned to three groups (each group 9 subjects): 1. HIIT (...

  9. The anaerobic endurance of elite soccer players improved after a high-intensity training intervention in the 8-week conditioning program.

    Science.gov (United States)

    Sporis, Goran; Ruzic, Lana; Leko, Goran

    2008-03-01

    The purpose of this study was to evaluate changes in anaerobic endurance in elite First-league soccer players throughout 2 consecutive seasons, in 2 phases, with and without high-intensity situational drills. Eighteen soccer players were tested before and after the 8-week summer conditioning and again in the next season. The measured variables included 300-yard shuttle run test, maximal heart rate, and maximal blood lactate at the end of the test. During the first phase of the study, the traditional sprint training was performed only 2 x weeks and consisted of 15 bouts of straight-line sprinting. In the second year the 4 x 4 min drills at an intensity of 90-95% of HRmax, separated by periods of 3-minute technical drills at 55-65% of HRmax were introduced. Statistical significance was set at P sprinting in improving anaerobic endurance measured by the 300-yard shuttle run test.

  10. The Effect of 8 Weeks Aerobic Training on the Social Adjustment in Mentally Retarded Children with Hemiplegic Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Zahra Pooraghaei Ardakani

    2015-10-01

    Full Text Available One of the most important and basic problems in mentally retarded children which can form the basis of their behavior is impairment in social adjustment and performance. The purpose of the present work was to study the effect of 8 weeks aerobic training on the social adjustment in mentally retarded children with hemiplegic cerebral palsy. The statistical population included all mentally retarded children with hemiplegic cerebral palsy in District 1 of Tehran who were under the coverage of Exceptional Education Organization in 2013-2014 academic year. Among 38 mentally retarded children, 24 (with a mean age of 9±2 years were randomly selected and divided into two groups: experimental and the control groups. To assess the social adjustment, Vineland Adjustment Behavior Scale (VABS (1984 was used. Quasi-experimental method with pretest and posttest design and a control group was used for this research. The findings showed that 8 weeks aerobic exercises could increase the social adjustment in children with hemiplegic cerebral palsy (P≤0.001. Finally, it can be concluded that aerobic exercises have a positive impact on the social adjustment in children with hemiplegic cerebral palsy by increasing their communication with peers.

  11. Effect of 8 weeks sprint interval training on serum levels of Adiponectin and insulin in overweight children

    Directory of Open Access Journals (Sweden)

    Abdolreza Kazemi

    2016-04-01

    Full Text Available Background: Scientific studies demonstrated that decreased blood Adiponectin level is associated with insulin resistance in obesity. Also it is well documented that exercise training exerts beneficial effects on obesity but there is few study regarding beneficial effects of sprint Interval training (SIT on childhood obesity. This study was intended to investigate the effect of SIT on serum levels of Adiponectin and insulin in overweight children. Material and Methods: In this study thirty-two obese boy (BMI=27 were randomly assigned to sprint Interval Training (SIT (N=16 and control group(C (N=16. Training protocol consisted of 30s and 90s all-out running that performed 3 sessions per week for 8 weeks. Blood samples were measured by ELISA analysis. Data were analyzed using Independent sample t-test. Results: 8 weeks SIT increase serum levels of Adiponectin (P=0.028 and decrease insulin level (P=0.00. This change was directly related to decrease in values of BMI (P=0.01, total cholesterol (P=0.00 and body weight (P=0.02, but significant change in serum levels of HDL (P=0.50, LDL (P=0.17 and TG (P=0.60 wasn’t observed. Conclusion: These findings suggest that SIT may ameliorate the metabolic abnormalities associated with obesity in children probably through elevation of serum Adiponectin level.

  12. Atomoxetine treatment may decrease striatal dopaminergic transporter availability after 8 weeks: pilot SPECT report of three cases

    Directory of Open Access Journals (Sweden)

    Akay AP

    2015-11-01

    Full Text Available Aynur Pekcanlar Akay,1 Gamze Capa Kaya,2,3 Burak Baykara,1 Yusuf Demir,2,3 Handan Özek,1 Sevay Alsen,1 Mine Sencan Eren,2,3 Neslihan Inal Emiroglu,1 Turkan Ertay,2,3 Yesim Ozturk,4 Suha Miral,1 Hatice Durak,2,3 Evren Tufan4 1Department of Child and Adolescent Psychiatry, 2Department of Nuclear Medicine, 3Department of Pediatrics, Dokuz Eylul University Medical Faculty, Izmir, 4Department of Child and Adolescent Psychiatry, Abant İzzet Baysal University, Bolu, Turkey Abstract: Attention deficit/hyperactivity disorder is one of the most common neurodevelopmental disorders. The pathophysiology is thought to involve noradrenaline and dopamine. The role of dopamine transporter (DAT was evaluated in imaging studies using mostly dopamine reuptake inhibitors. Atomoxetine is a selective noradrenaline reuptake inhibitor. Here we report the results of a pilot study conducted to evaluate changes in striatal DAT after 8 weeks of atomoxetine treatment. Our results suggest that 8 weeks of atomoxetine treatment may change striatal DAT bioavailability as measured via SPECT but that change was not correlated with genotype or clinical improvement. Keywords: neuroimaging, dopamine, noradrenaline, SLC6A3 protein, human, pragmatic clinical trial, pilot study

  13. Resistance Exercise with concurrent whole body vibration preserves isometric knee extension strength during 8 weeks of horizontal bed rest

    Science.gov (United States)

    Mulder, E. R.; Stegeman, D. F.; Gerrits, K.; Rittweger, J.; Felsenberg, D.; de Haan, A.

    2005-08-01

    Changes in the quadriceps femoris (QF) muscle with respect to anatomical cross sectional area (CSA), neural activation level and isometric maximal voluntary torque (MVT) were determined in 18 healthy men subjected to 8 weeks of horizontal bed rest (BR) with (n = 9) and without (Ctrl; n = 9) 6 days/week resistance exercise concurrent with whole body vibration (RVE). For Ctrl, mean QF CSA decreased linearly over time to a reduction of 14.3 ± 4.9% at the end of BR. For RVE, exercise during BR significantly mitigated this reduction (3.9 ± 4.4%). Prior to and seven times during BR, MVT values were obtained together with neural activation levels, the latter by means of a superimposed stimulation technique. MVT was maintained for RVE during BR, whereas for Ctrl, MVT was significantly reduced by 14.2 ± 8.1% after 8 weeks. In contrast to previous reports, the maximal voluntary activation remained unaltered for both groups throughout the study. For Ctrl, the absence of a change in neural activation might be related to the repeated testing during the bed rest, which had presumably resulted in a habituation to the task. When both groups were pooled, a significant positive correlation (R= 0.62; P < 0.01) was observed between changes in CSA and changes in MVT.

  14. The Effect of 8 weeks of combined training on the angle of lumbar lordosis and pain of women suffering from sciatica pain

    Directory of Open Access Journals (Sweden)

    Behnaz Karimi

    2016-11-01

    Full Text Available Chronic low back pain is among the most commonly pains caused by malfunctions, poor physical condition, and mental stresses. Various non-surgical methods are recommended to reduce pain, to maintain mobility, and to minimize disability in patients. The main objective of this study was to determine the impact of 8 weeks of combined exercises on lumbar lordosis angle, pain, and quality of life of females suffering from sciatic pain. In this study, 15 female patients participated aged between 30 and 50 years with low back pain, sciatic pain, and lumbar lordosis. Lumbar lordosis angle (flexible ruler and pain (McGill questionnaire of patients before and after 8 weeks of exercise were evaluated. Data were analyzed using t-test (P<0.05. In this study, no significant difference was found in lumbar lordosis angle of sciatica patients before (± 0.1 43.2 and after the exercises (0.8 ± 34.2 (p<0.05.Significant difference was observed in pain perceptions between the before (0.8 ± 2.6 and after exercises (0.5 ± 1.8, emotional perceptions of pain between before (0.26 ± 1.4 and after exercises (0.3 ± 1.9 and various pain perceptions between before (0.6 ± 2.2 and after exercises (0.2 ± 1.5 (P<0.05. It can be concluded that hydrotherapy exercises along with on land exercises can improve lumbar lordosis and pain in patients with sciatic pain. Therefore, it can be recommended as a modality for these patients.

  15. Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.

    Science.gov (United States)

    Ritsner, Michael S; Gibel, Anatoly; Shleifer, Tatyana; Boguslavsky, Igor; Zayed, Ahmad; Maayan, Rachel; Weizman, Abraham; Lerner, Vladimir

    2010-10-01

    Pregnenolone (PREG) and dehydroepiandrosterone (DHEA) are reported to have a modulatory effect on neuronal excitability, synaptic plasticity, and response to stress; they are associated with mood regulation and cognitive performance. We investigated the influence of PREG and DHEA on psychotic symptoms and cognitive functioning as an add-on to ongoing antipsychotic treatment of patients with chronic schizophrenia or schizoaffective disorder. This 8-week, double-blind, randomized, placebo-controlled, 2-center study compared 30 mg/d of PREG (PREG-30), 200 mg/d of PREG (PREG-200), 400 mg/d of DHEA, and placebo as an adjunctive treatment of 58 chronic schizophrenia or schizoaffective disorder patients (DSM-IV). The data were collected from February 2005 until June 2007. The outcome measures were symptomatic and neurocognitive changes, functioning, and tolerability as assessed primarily by the Clinical Global Impressions-Severity of Illness scale and the Positive and Negative Syndrome Scale. Analyses are presented for 44 patients who completed 8 weeks of treatment and for 14 noncompleters. Compared with subjects who received placebo, those administered PREG-30 had significant reductions in positive symptom scores and extrapyramidal side effects (EPS) and improvement in attention and working memory performance, whereas subjects treated with PREG-200 did not differ on outcome variable scores for the study period. The general psychopathology severity and general functioning of patients receiving placebo and PREG-30 improved more than that of those subjects treated with DHEA, while EPS improved more in subjects treated with DHEA than in patients receiving placebo. Negative symptoms and akathisia were not significantly benefited by any treatment. The administration of PREG and DHEA was well tolerated. Low-dose PREG augmentation demonstrated significant amelioration of positive symptoms and EPS and improvement in attention and working memory performance of schizophrenia and

  16. Effect of levitra on sustenance of erection (EROS): an open-label, prospective, multicenter, single-arm study to investigate erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction.

    Science.gov (United States)

    Shin, Y S; Lee, S W; Park, K; Chung, W S; Kim, S W; Hyun, J S; Moon, D G; Yang, S-K; Ryu, J K; Yang, D Y; Moon, K H; Min, K S; Park, J K

    2015-01-01

    To investigate the change of erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction (ED). Effect of levitra on sustenance of erection was an open-label, prospective, multicenter and single-arm study designed to measure the duration of erection in men with ED receiving a flexible dose of vardenafil over an 8-week treatment period. Patients were instructed to take vardenafil 10 mg 60 min before attempting the intercourse. Vardenfil could be increased to 20 mg or decreased to 5 mg concerning patients' efficacy and safety. Following the initial screening, patients entered a 4-week treatment-free run-in phase and 8-week treatment period, during which they were instructed to attempt intercourse at least four times on four separate days. A total of 95 men were enrolled in 10 centers. After the 8 weeks treatment, the mean duration of erection leading to successful intercourse was statistically superior when patients were treated with vardenafil. After an 8-week treatment, the duration of erection leading to successful intercourse was 9.39 min. There were significant benefits with vardenafil in all domains of International Index of Erectile Function. Secondary efficacy end points included success rate of penetration, maintaining erection, ejaculation and satisfaction were superior when patients were treated with vardenafil. There was a significant correlation between duration of erection with other sexual factors. Also partner's sexual satisfaction was increased with vardenafil. Most adverse events were mild or moderate in severity. Vardenafil was safe and well tolerated. Vardenafil therapy provided a statistically superior duration of erection leading to successful intercourse in men with ED with female partner.

  17. Analysis of Characteristics of the Rural Political Participation in Yan’an Period

    Institute of Scientific and Technical Information of China (English)

    Hongwei YUAN

    2015-01-01

    From October 1935 when the Central Red Army arrived in northern Shaanxi to March 1948 when the Central Committee of the Communist Party of China crossed the Yellow River,the Communist Party of China inspired ordinary party members’ political participation consciousness through rectification and seeking the opinions of non-party individuals,and stimulated the political participation enthusiasm of democracy activists through the special election to improve farmers’ political participation awareness,in order to form a unique " Yan’an democratic model",which greatly accelerated the victory of the resistance war and accumulated rich experience for democratic construction.

  18. Dietary self-monitoring, but not dietary quality, improves with use of smartphone app technology in an 8-week weight loss trial.

    Science.gov (United States)

    Wharton, Christopher M; Johnston, Carol S; Cunningham, Barbara K; Sterner, Danielle

    2014-01-01

    Dietary self-monitoring is linked to improved weight loss success. Mobile technologies, such as smartphone applications (apps), might allow for improved dietary tracking adherence. The authors assessed the use of a popular smartphone app for dietary self-monitoring and weight loss by comparing it with traditional diet counseling and entry methods. Diet tracking and weight loss were compared across participants during an 8-week weight loss trial. Participants tracked intake using 1 of 3 methods: the mobile app "Lose It!", the memo feature on a smartphone, or a traditional paper-and-pencil method. App users (n = 19) recorded dietary data more consistently compared with the paper-and-pencil group (n = 15; P = .042) but not the memo group (n = 13). All groups lost weight over the course of the study (P = .001), and no difference in weight loss was noted between groups. Smartphone apps could represent a novel and feasible dietary self-monitoring method for individuals. Copyright © 2014 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  19. Hospital expenditure as a major driver of nurse labour force participation: evidence from a 10-year period in Canada.

    Science.gov (United States)

    Vujicic, Marko; Onate, Kanecy; Laporte, Audrey; Deber, Raisa

    2011-05-01

    This paper examines trends in the nursing labour market in Canada over a period of dramatic fluctuations in hospital expenditures. We add to previous analysis that covered the period 1991-1996 and use Census data from 2001 to examine the relationship between hospital expenditure and nurse labour force participation. We find that shifts in labour force participation over the period 1991-2001 had a significant impact on the nursing supply in Canada. Individuals who were trained in nursing but were working outside the profession in 1996 because of budgetary reductions and layoffs in hospitals had largely been reabsorbed back into nursing jobs by 2001. Our analysis provides further empirical evidence that the labour force participation among individuals trained in nursing is driven to a large extent by demand-side factors.

  20. Description of exercise participation of adolescents with cerebral palsy across a 4-year period.

    Science.gov (United States)

    Brunton, Laura K; Bartlett, Doreen J

    2010-01-01

    The purposes of this study were to describe (1) the types of exercise participation of adolescents with cerebral palsy; (2) the weekly duration of stretching, strengthening, and cardiovascular exercise; (3) how the level of activity compares with national health guidelines; and (4) the change in participation over 4 years. Participants included 126 males and 104 females (mean age = 14.7 years, SD = 1.7 years) who reported physical activities in the previous week. Analyses included frequency counts and proportions, stacked bar graphs, and 2-way analyses of variance of exercise participation by Gross Motor Function Classification System (GMFCS) and sex. A significant main effect of GMFCS level was detected for light and moderate exercise. A significant interaction of GMFCS level and sex was found for stretching; females stretched more. An average of 9.4% and 11.4% of our sample participated in weekly levels of moderate and vigorous exercise, respectively. Pediatric physical therapists should promote increased exercise participation rates among youths with cerebral palsy.

  1. Long-term clinical benefit and cost-effectiveness of an 8-week multimodal knee osteoarthritis management program incorporating intra-articular sodium hyaluronate (Hyalgan® injections

    Directory of Open Access Journals (Sweden)

    Miller LE

    2017-05-01

    Full Text Available Larry E Miller,1 Michael J Sloniewsky,2 Thomas E Gibbons,3 Janice G Johnston,4 Kent D Vosler,4 Saad Nasir5 1Miller Scientific Consulting, Inc., Asheville, NC, 2RMG Holding, Inc., Florence, 3Doctors Care, PA, Columbia, SC, 4Arrowhead Health Centers, Glendale, AZ, 5Fidia Pharma USA Inc., Parsippany, NJ, USA Background: Given the poor long-term effectiveness of focused nonsurgical knee osteoarthritis (OA treatments, alternative therapies are needed for patients who have unsuccessfully exhausted nonsurgical options.Methods: A telephone interview was conducted in patients who participated in a single 8-week multimodal knee OA treatment program (mean follow-up: 3.7 years, range: 2.7–4.9 years. The program consisted of five intra-articular knee injections of sodium hyaluronate (Hyalgan®, with each injection given 1 week apart, structured physical therapy, knee bracing, and patient education. Clinical outcomes included knee pain severity, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC subscores, current medication use, and history of total knee arthroplasty. Base-case, subgroup, and sensitivity analyses were conducted to determine the incremental cost-effectiveness ratio (ICER of the treatment program with comparisons made to historical literature controls undergoing usual care. Results: A total of 218 patients (54% provided long-term follow-up data. Knee pain severity decreased 60% and WOMAC subscores decreased 33%–42% compared to baseline (all p<0.001. Total knee arthroplasty was performed in 22.8% (81/356 of knees during follow-up. The treatment program was highly cost-effective compared to usual care with a base-case ICER of $6,000 per quality-adjusted life year (QALY. Results of subgroup analyses, one-way deterministic sensitivity analyses, and second-order probabilistic sensitivity analyses resulted in ICERs ranging from $3,996 to $10,493 per QALY. The percentage of simulations with an ICER below willingness

  2. A Comparison of Increases in Volume Load Over 8 Weeks of Low-Versus High-Load Resistance Training.

    Science.gov (United States)

    Schoenfeld, Brad J; Ogborn, Dan; Contreras, Bret; Cappaert, Tom; Silva Ribeiro, Alex; Alvar, Brent A; Vigotsky, Andrew D

    2016-06-01

    It has been hypothesized that the ability to increase volume load (VL) via a progressive increase in the magnitude of load for a given exercise within a given repetition range could enhance the adaptive response to resistance training. The purpose of this study was to compare changes in volume load (VL) over eight weeks of resistance training (RT) in high-versus low-load protocols. Eighteen well-trained men were matched according to baseline strength were randomly assigned to either a low-load RT (LOW, n = 9) where 25 - 35 repetitions were performed per exercise, or a high-load RT (HIGH, n = 9) where 8 - 12 repetitions were performed per exercise. Both groups performed three sets of seven exercises for all major muscles three times per week on non-consecutive days. After adjusting for the pre-test scores, there was a significant difference between the two intervention groups on post-intervention total VL with a very large effect size (F (1, 15) = 16.598, P = .001, ηp(2) = .525). There was a significant relationship between pre-intervention and post-intervention total VL (F (1, 15) = 32.048, P < .0001, ηp(2) = .681) in which the pre-test scores explained 68% of the variance in the post-test scores. This study indicates that low-load RT results in greater accumulations in VL compared to high-load RT over the course of 8 weeks of training.

  3. Relationship among serum taurine, serum adipokines, and body composition during 8-week human body weight control program.

    Science.gov (United States)

    You, Jeong Soon; Park, Ji Yeon; Zhao, Xu; Jeong, Jin Seok; Choi, Mi Ja; Chang, Kyung Ja

    2013-01-01

    Human adipose tissue is not only a storage organ but also an active endocrine organ to release adipokines. This study was conducted to investigate the relationship among serum taurine and adipokine levels, and body composition during 8-week human body weight control program in obese female college students. The program consisted of diet therapy, exercise, and behavior modification. After the program, body weight, body fat mass, percent body fat, and body mass index (BMI) were significantly decreased. Serum triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) levels were significantly decreased. Also serum adiponectin level was significantly increased and serum leptin level was significantly decreased. There were no differences in serum taurine and homocysteine levels. The change of serum adiponectin level was positively correlated with change of body fat mass and percent body fat. These results may suggest that body fat loss by human body weight control program is associated with an increase in serum adiponectin in obese female college students. Therefore, further study such as taurine intervention study is needed to know more exact correlation between dietary taurine intake and serum adipokines or body composition.

  4. Effect of 8 weeks Resistance Training on BDNF and TrkB in the Hippocampus of Adult Male Rats

    Directory of Open Access Journals (Sweden)

    S Mojtahedi

    2014-08-01

    Full Text Available Background & aim: Exercise enhances the synaptic plasticity and neuroprotective effects in the adult brain. However, it remains unknown that how plasticity molecules change following types of training. The purpose of this study was to determine the effect of eight weeks resistance training on protein levels of Brain Derived Neurotrophic Factor(BDNF and receptor of TrkB, in the hippocampus of adult male rats. Methods: In this experimental study, twelve adult male rats, 8 weeks of age, with an average weight of 200 to 225 grams were randomly divided into two groups, control and exercise respectively. The exercise was to increase the weight on the ladder. 24 hours after their last training session. The animals were killed and the hippocampus was removed for further testing. ELISA determined changes in protein levels. Data were analyzed by independent t test. Results: There was a significant difference between train and control groups In protein level of variables statically (p≤0.05. In addition, protein levels of BDNF and TrkB in the hippocampus of rats increased. Conclusion: Resistance training is beneficial for promoting hippocampal plasticity associated with BDNF signaling and consequently functional and cognitive benefits.

  5. 32 CFR 37.665 - Must I require nonprofit participants to have periodic audits?

    Science.gov (United States)

    2010-07-01

    ... nonprofit organizations. Note that those requirements also are appropriate for Government-owned, contractor... from the definition of “recipient” in 32 CFR part 32, because nonprofit GOCOs and FFRDCs are subject to... 32 National Defense 1 2010-07-01 2010-07-01 false Must I require nonprofit participants to...

  6. Increases in the right dorsolateral prefrontal cortex and decreases the rostral prefrontal cortex activation after-8 weeks of focused attention based mindfulness meditation.

    Science.gov (United States)

    Tomasino, Barbara; Fabbro, Franco

    2016-02-01

    Mindfulness meditation is a form of attention control training. The training exercises the ability to repeatedly focus attention. We addressed the activation changes related to an 8-weeks mindfulness-oriented focused attention meditation training on an initially naïve subject cohort. Before and after training participants underwent an fMRI experiment, thus, although not strictly a cross over design, they served as their internal own control. During fMRI they exercised focused attention on breathing and body scan as compared to resting. We found increased and decreased activation in different parts of the prefrontal cortex (PFC) by comparing pre- vs. post-mindfulness training (MT) during breathing and body scan meditation exercises that were compared against their own resting state. In the post-MT (vs. pre-MT) meditation increased activation in the right dorsolateral PFC and in the left caudate/anterior insula and decreased activation in the rostral PFC and right parietal area 3b. Thus a brief mindfulness training caused increased activation in areas involved in sustaining and monitoring the focus of attention (dorsolateral PFC), consistent with the aim of mindfulness that is exercising focused attention mechanisms, and in the left caudate/anterior insula involved in attention and corporeal awareness and decreased activation in areas part of the "default mode" network and is involved in mentalizing (rostral PFC), consistent with the ability trained by mindfulness of reducing spontaneous mind wandering.

  7. Pain trajectory and exercise-induced pain flares during 8 weeks of neuromuscular exercise in individuals with knee and hip pain

    DEFF Research Database (Denmark)

    Sandal, L F; Roos, E M; Bøgesvang, S J

    2016-01-01

    OBJECTIVE: Patients considering or engaged in exercise as treatment may expect or experience transient increases in joint pain, causing fear of exercise and influencing compliance. This study investigated the pain trajectory during an 8-week neuromuscular exercise (NEMEX) program together...

  8. Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: testing the "adipose tissue expandability" hypothesis.

    Science.gov (United States)

    Johannsen, Darcy L; Tchoukalova, Yourka; Tam, Charmaine S; Covington, Jeffrey D; Xie, Wenting; Schwarz, Jean-Marc; Bajpeyi, Sudip; Ravussin, Eric

    2014-10-01

    The presence of large subcutaneous adipocytes in obesity has been proposed to be linked with insulin resistance and type 2 diabetes through the "adipose tissue expandability" hypothesis, which holds that large adipocytes have a limited capacity for expansion, forcing lipids to be stored in nonadipose ectopic depots (skeletal muscle, liver), where they interfere with insulin signaling. This hypothesis has, however, been largely formulated by cross-sectional findings and to date has not been prospectively demonstrated in the development of insulin resistance in humans. Twenty-nine men (26.8 ± 5.4 years old; BMI 25.5 ± 2.3 kg/m(2)) were fed 40% more than their baseline requirement for 8 weeks. Before and after overfeeding, insulin sensitivity was determined using a two-step hyperinsulinemic-euglycemic clamp. Intrahepatic lipid (IHL) and intramyocellular lipid (IMCL) were measured by (1)H-MRS and abdominal fat by MRI. Subcutaneous abdominal adipose and skeletal muscle tissues were collected to measure adipocyte size and markers of tissue inflammation. Subjects gained 7.6 ± 2.1 kg (55% fat) and insulin sensitivity decreased 18% (P insulin sensitivity, which was linked with upregulated skeletal muscle tissue inflammation. In experimental substantial weight gain, the presence of larger adipocytes did not promote ectopic lipid accumulation. In contrast, smaller fat cells were associated with a worsened metabolic response to overfeeding. © 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

  9. The effect of 8 weeks of endurance training on hypothalamic Nesfatin-1 gene expression and its concentration in male rats

    Directory of Open Access Journals (Sweden)

    Abbas Ghanbari Niaki

    2012-09-01

    Full Text Available Background: Hypothalamus is mentioned as the major center of appetite and energy balance. Physical activity and the exersice are able to disturb the energy balance to negative. Nesfatin-1 is a regulating neuropeptide that is produced by hypothalamus and has an important role in establishing energy balance. The purpose of this study was to examine the effect of endurance training regimen on nesfatin-1 gene expression and its concentration in the male rat hypothalamus. Materials and Methods: Eleven adult wistar male rats (8-10 week old, 130-145g assigned into control(C, n=5 and training (E, n=6 groups. Training group was given exercise on a motor-driven treadmill (20m/min, 0% grade, 60 min/session, 5days/week for 8 weeks. Rats were sacrificed 72h after the last training session and then the hypothalamus tissue was excised for determination of nesfatin-1 gene expression and its concentration by RT-PCR & ELIZA methods, respectively. Four hours before the experiment the food not tap water was removed from the animal cages. Data was analyzed by using an independent t-student test. Results: The current results indicated that the levels of nesfatin-1 gene expression and its concentration, ATP, and glycogen concentrations were non-significantly lower in trained group when compared with control group. Conclusion: This research showed for the first time, that a low-intensity exercises, decreases nesfatin-1 expression and concentration in the hypothalamus, which accompanied insignificant reduction in energy source. It seems that in the present research, the exercise has had the same fasting and being hungry like effect on nesfatin-1 expression and concentration in the hypothalamus.

  10. A Comparison of Increases in Volume Load Over 8 Weeks of Low-Versus High-Load Resistance Training

    Directory of Open Access Journals (Sweden)

    Schoenfeld

    2016-01-01

    Full Text Available Background It has been hypothesized that the ability to increase volume load (VL via a progressive increase in the magnitude of load for a given exercise within a given repetition range could enhance the adaptive response to resistance training. Objectives The purpose of this study was to compare changes in volume load (VL over eight weeks of resistance training (RT in high-versus low-load protocols. Materials and Methods Eighteen well-trained men were matched according to baseline strength were randomly assigned to either a low-load RT (LOW, n = 9 where 25 - 35 repetitions were performed per exercise, or a high-load RT (HIGH, n = 9 where 8 - 12 repetitions were performed per exercise. Both groups performed three sets of seven exercises for all major muscles three times per week on non-consecutive days. Results After adjusting for the pre-test scores, there was a significant difference between the two intervention groups on post-intervention total VL with a very large effect size (F (1, 15 = 16.598, P = .001, ηp2 = .525. There was a significant relationship between pre-intervention and post-intervention total VL (F (1, 15 = 32.048, P < .0001, ηp2 = .681 in which the pre-test scores explained 68% of the variance in the post-test scores. Conclusions This study indicates that low-load RT results in greater accumulations in VL compared to high-load RT over the course of 8 weeks of training.

  11. Sertraline and rapid eye movement sleep without atonia: an 8-week, open-label study of depressed patients.

    Science.gov (United States)

    Zhang, Bin; Hao, Yanli; Jia, Fujun; Tang, Yi; Li, Xueli; Liu, Wuhan; Arnulf, Isabelle

    2013-12-02

    Previous studies have reported that selective serotonin reuptake inhibitors (SSRIs) may induce or exacerbate rapid eye movement (REM) sleep without atonia (RSWA) and increase the risk of developing REM sleep behavior disorder (RBD). However, most of these studies are retrospective and cross-sectional and employed small sample sizes and a mixture of SSRIs. In this 8-week open-label trial of sertraline in depressed patients (n = 31), depressed patients were administered 50mg sertraline at 8 am on the 1st day and subsequently titrated up to a maximum of 200mg/day. All patients underwent repeated video-polysomnography (vPSG) (baseline, 1st day, 14th day, 28th day, and 56th day). Both tonic (submental) and phasic (submental and anterior tibialis) RSWA events were visually counted. Tonic RSWA increased from 3.2 ± 1.8% at baseline to 5.1 ± 2.3% on the 1st day and 10.4 ± 2.7% on the 14th day; after that, measurements were stable until the 56th day. A similar profile was observed for phasic RSWA. The increases in tonic RSWA (r = 0.56, P = 0.004) and phasic RSWA (submental: r = -0.51, P = 0.02; anterior tibialis: r = 0.41, P = 0.04) were correlated with the degree of the prolonging of REM latency. All of RSWAs were not correlated with patients' demographic and clinical characteristics. Sertraline may induce or exacerbate RSWA. In contrast to idiopathic RBD, sertraline-related RSWA had the specific characteristics of being correlated with the degree of the prolonging of REM latency and no predominance of male sex and elder age, suggesting different pathophysiological mechanisms. The antidepressant-related RSWA should be a potential public health problem in the depressed patients.

  12. Effect of an 8-week practice of externally triggered speech on basal ganglia activity of stuttering and fluent speakers.

    Science.gov (United States)

    Toyomura, Akira; Fujii, Tetsunoshin; Kuriki, Shinya

    2015-04-01

    The neural mechanisms underlying stuttering are not well understood. It is known that stuttering appears when persons who stutter speak in a self-paced manner, but speech fluency is temporarily increased when they speak in unison with external trigger such as a metronome. This phenomenon is very similar to the behavioral improvement by external pacing in patients with Parkinson's disease. Recent imaging studies have also suggested that the basal ganglia are involved in the etiology of stuttering. In addition, previous studies have shown that the basal ganglia are involved in self-paced movement. Then, the present study focused on the basal ganglia and explored whether long-term speech-practice using external triggers can induce modification of the basal ganglia activity of stuttering speakers. Our study of functional magnetic resonance imaging revealed that stuttering speakers possessed significantly lower activity in the basal ganglia than fluent speakers before practice, especially when their speech was self-paced. After an 8-week speech practice of externally triggered speech using a metronome, the significant difference in activity between the two groups disappeared. The cerebellar vermis of stuttering speakers showed significantly decreased activity during the self-paced speech in the second compared to the first experiment. The speech fluency and naturalness of the stuttering speakers were also improved. These results suggest that stuttering is associated with defective motor control during self-paced speech, and that the basal ganglia and the cerebellum are involved in an improvement of speech fluency of stuttering by the use of external trigger. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. The effects of 8 weeks of motor skill training on cardiorespiratory fitness and endurance performance in children with developmental coordination disorder.

    Science.gov (United States)

    Farhat, Faiçal; Masmoudi, Kaouthar; Hsairi, Ines; Smits-Engelsman, Bouwien C M; Mchirgui, Radhouane; Triki, Chahnez; Moalla, Wassim

    2015-12-01

    Interventions based on everyday motor skills have been developed to be effective in children with developmental coordination disorder (DCD). The purpose of the present study was to examine the effects of motor skill training on exercise tolerance and cardiorespiratory fitness in children with DCD. Children were assigned to 3 groups: an experimental training group comprising 14 children with DCD, a control nontraining group comprising 13 children with DCD, and a control nontraining group comprising 14 typically developed children. All participants were tested twice with an interval of 8-weeks on a cardiopulmonary exercise test, pulmonary function testing, and a 6-min walk test. After the training program the maximal power output was significantly increased for DCD group at anaerobic threshold (p < 0.05) and at peak level (maximal oxygen uptake, p < 0.001). Improvement in power output was more pronounced at the anaerobic threshold (t (13) = -5.21, p < 0.001) than at the maximal intensity (maximal oxygen uptake, t (13) = -3.08, p < 0.01) in the DCD training group. Children with DCD that participated in the training program improved their walking distance (t (13) = -9.08, p < 0.001), had a higher maximum heart rate (t (13) = -3.41, p < 0.01), and reduced perceived exertion (t (13) = 2.75, p < 0.05). The DCD nontraining group and the typically developed group did not change on any of the measures. In conclusion, training delayed reaching the anaerobic threshold and improved aerobic endurance and exercise tolerance in children with DCD.

  14. Performance of the participant laboratories in the National Intercomparison Program (PNI) in the period from 1991 to 2013

    Energy Technology Data Exchange (ETDEWEB)

    Tauhata, Luiz; Vianna, Maria Elizabeth Couto Machado; Oliveira, Antonio Eduardo de; Braganca, Maura Julia Camara da Silva; Ferreira, Ana Cristina de Melo, E-mail: maura@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2015-07-01

    The statistical evaluation of the data of 23 years of the Brazilian Intercomparison Program shows the performance of the 24 Participant Laboratories of the country in the determination of 29 radionuclides in 10600 spiked samples of low level activity values. The results were shown a good performance and an evolution of the quality control for analyses of this kind of samples in this time period. (author)

  15. Changes in Disability, Physical/Mental Health States and Quality of Life during an 8-Week Multimodal Physiotherapy Programme in Patients with Chronic Non-Specific Neck Pain: A Prospective Cohort Study

    Science.gov (United States)

    Cuesta-Vargas, Antonio Ignacio; González-Sánchez, Manuel

    2015-01-01

    Aim The aim of this study was to analyse the effect of an 8-week multimodal physiotherapy programme (MPP), integrating physical land-based therapeutic exercise (TE), adapted swimming and health education, as a treatment for patients with chronic non-specific neck pain (CNSNP), on disability, general health/mental states and quality of life. Methods 175 CNSNP patients from a community-based centre were recruited to participate in this prospective study. Intervention: 60-minute session (30 minutes of land-based exercise dedicated to improving mobility, motor control, resistance and strengthening of the neck muscles, and 30 minutes of adapted swimming with aerobic exercise keeping a neutral neck position using a snorkel). Health education was provided using a decalogue on CNSNP and constant repetition of brief advice by the physiotherapist during the supervision of the exercises in each session. Study outcomes: primary: disability (Neck Disability Index); secondary: physical and mental health states and quality of life of patients (SF-12 and EuroQoL-5D respectively). Differences between baseline data and that at the 8-week follow-up were calculated for all outcome variables. Results Disability showed a significant improvement of 24.6% from a mean (SD) of 28.2 (13.08) at baseline to 16.88 (11.62) at the end of the 8-week intervention. All secondary outcome variables were observed to show significant, clinically relevant improvements with increase ranges between 13.0% and 16.3% from a mean of 0.70 (0.2) at baseline to 0.83 (0.2), for EuroQoL-5D, and from a mean of 40.6 (12.7) at baseline to 56.9 (9.5), for mental health state, at the end of the 8-week intervention. Conclusion After 8 weeks of a MPP that integrated land-based physical TE, health education and adapted swimming, clinically-relevant and statistically-significant improvements were observed for disability, physical and mental health states and quality of life in patients who suffer CNSNP. The clinical

  16. Changes in disability, physical/mental health states and quality of life during an 8-week multimodal physiotherapy programme in patients with chronic non-specific neck pain: a prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Antonio Ignacio Cuesta-Vargas

    Full Text Available The aim of this study was to analyse the effect of an 8-week multimodal physiotherapy programme (MPP, integrating physical land-based therapeutic exercise (TE, adapted swimming and health education, as a treatment for patients with chronic non-specific neck pain (CNSNP, on disability, general health/mental states and quality of life.175 CNSNP patients from a community-based centre were recruited to participate in this prospective study.60-minute session (30 minutes of land-based exercise dedicated to improving mobility, motor control, resistance and strengthening of the neck muscles, and 30 minutes of adapted swimming with aerobic exercise keeping a neutral neck position using a snorkel. Health education was provided using a decalogue on CNSNP and constant repetition of brief advice by the physiotherapist during the supervision of the exercises in each session.primary: disability (Neck Disability Index; secondary: physical and mental health states and quality of life of patients (SF-12 and EuroQoL-5D respectively. Differences between baseline data and that at the 8-week follow-up were calculated for all outcome variables.Disability showed a significant improvement of 24.6% from a mean (SD of 28.2 (13.08 at baseline to 16.88 (11.62 at the end of the 8-week intervention. All secondary outcome variables were observed to show significant, clinically relevant improvements with increase ranges between 13.0% and 16.3% from a mean of 0.70 (0.2 at baseline to 0.83 (0.2, for EuroQoL-5D, and from a mean of 40.6 (12.7 at baseline to 56.9 (9.5, for mental health state, at the end of the 8-week intervention.After 8 weeks of a MPP that integrated land-based physical TE, health education and adapted swimming, clinically-relevant and statistically-significant improvements were observed for disability, physical and mental health states and quality of life in patients who suffer CNSNP. The clinical efficacy requires verification using a randomised controlled study

  17. Effects of an 8-week yoga program on sustained attention and discrimination function in children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Chien-Chih Chou

    2017-01-01

    Full Text Available This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years were assigned to either a yoga exercise or a control group. Participants were given the Visual Pursuit Test and Determination Test prior to and after an eight-week exercise intervention (twice per week, 40 min per session or a control intervention. Significant improvements in accuracy rate and reaction time of the two tests were observed over time in the exercise group compared with the control group. These findings suggest that alternative therapies such as yoga exercises can be complementary to behavioral interventions for children with attention and inhibition problems. Schools and parents of children with ADHD should consider alternatives for maximizing the opportunities that children with ADHD can engage in structured yoga  exercises.

  18. Effects of an 8-week yoga program on sustained attention and discrimination function in children with attention deficit hyperactivity disorder

    Science.gov (United States)

    Chou, Chien-Chih

    2017-01-01

    This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years) were assigned to either a yoga exercise or a control group. Participants were given the Visual Pursuit Test and Determination Test prior to and after an eight-week exercise intervention (twice per week, 40 min per session) or a control intervention. Significant improvements in accuracy rate and reaction time of the two tests were observed over time in the exercise group compared with the control group. These findings suggest that alternative therapies such as yoga exercises can be complementary to behavioral interventions for children with attention and inhibition problems. Schools and parents of children with ADHD should consider alternatives for maximizing the opportunities that children with ADHD can engage in structured yoga  exercises. PMID:28097075

  19. Effect of Micronutrients on Behavior and Mood in Adults with ADHD: Evidence from an 8-Week Open Label Trial with Natural Extension

    Science.gov (United States)

    Rucklidge, Julia; Taylor, Mairin; Whitehead, Kathryn

    2011-01-01

    Objective: To investigate the effect of a 36-ingredient micronutrient formula consisting mainly of minerals and vitamins in the treatment of adults with both ADHD and severe mood dysregulation (SMD). Method: 14 medication-free adults (9 men, 5 women; 18-55 years) with ADHD and SMD completed an 8-week open-label trial. Results: A minority reported…

  20. Effect of Micronutrients on Behavior and Mood in Adults with ADHD: Evidence from an 8-Week Open Label Trial with Natural Extension

    Science.gov (United States)

    Rucklidge, Julia; Taylor, Mairin; Whitehead, Kathryn

    2011-01-01

    Objective: To investigate the effect of a 36-ingredient micronutrient formula consisting mainly of minerals and vitamins in the treatment of adults with both ADHD and severe mood dysregulation (SMD). Method: 14 medication-free adults (9 men, 5 women; 18-55 years) with ADHD and SMD completed an 8-week open-label trial. Results: A minority reported…

  1. The Influence of 8 Weeks of Whey-Protein and Leucine Supplementation on Physical and Cognitive Performance

    Science.gov (United States)

    2010-01-01

    branchecl -chain mino ac ids ( BCAA ) may a lso improve cogni t ive per formance dur ing latigue. Blornstrand, Hassmdn, Eckblorn, and News- holme (1q91...1991) and Hassmdn, Blornstrand, Eck- blom, and Newsholme (1994) observecl that participants supplemented with BCAAs scored better on both mood lcvels...whey and casein, whey and BCAAs . or’ placebo ver’ I 0 weeks of R1’. ’fhey obser"ved a significant incrcase in l-RM BP in all 3 groups with no

  2. Immunosuppression for 6-8 weeks after modified donor lymphocyte infusion reduced acute graft-versus-host disease without influencing graft-versus-leukemia effect in haploidentical transplant

    Institute of Scientific and Technical Information of China (English)

    Yan Chenhua; Xu Lanping; Liu Daihong; Chen Huan; Wang Yu; Liu Kaiyan; Huang Xiaojun

    2014-01-01

    Background In haploidentical hematopoietic stem cell transplantation (HSCT),the duration of graft-versus-host disease (GVHD) prophylaxis after modified donor lymphocyte infusion (DLI) was the only risk factor of DLI-associated grades 3-4 acute GVHD.However,the successful application of modified DLI depended not only on the reduction of severe GVHD,but also on the preservation of graft-versus-leukemia (GVL) effect.Therefore,this study was performed to compare the impact of prophylaxis for 6-8 weeks and prophylaxis for <6 weeks on GVL effect after modified DLI in haploidentical HSCT.Methods A total of 103 consecutive patients developing hematological relapse or minimal residual disease (MRD)-positive status after haploidentical HSCT and receiving modified DLI were investigated retrospectively.Fifty-two patients received prophylaxis for 6-8 weeks after modified DLI; the remaining 51 patients received prophylaxis for <6 weeks.Results First,compared with prophylaxis for <6 weeks,prophylaxis for 6-8 weeks reduced incidence of relapse in total patients (26.6% vs.69.0%,P <0.001).Besides,prophylaxis for 6-8 weeks also reduced incidence of relapse in 54 patients developing hematological relapse post-transplant (P=0.018) and in 49 patients developing MRD-positive status post-transplant (P <0.001).Second,prophylaxis for 6-8 weeks reduced incidence of acute GVHD (P <0.05),reduced the therapeutic application of immunosuppressive agents (P=0.019),but increased the incidence of chronic GVHD (P<0.05).Third,prophylaxis for 6-8 weeks improved overall survival and disease-free survival in total patients,as well as in patients developing hematological relapse post-transplant and in patients developing MRD-positive status post-transplant (P <0.05).Conclusions In haploidentical HSCT,prophylaxis for 6-8 weeks after modified DLI does not reduce GVL effect,but reduces the incidence of DLI-associated acute GVHD compared with prophylaxis for <6 weeks.This strategy will

  3. The Seated Inactivity Trial (SIT): Physical Activity and Dietary Outcomes Associated With 8 Weeks of Imposed Sedentary Time.

    Science.gov (United States)

    Cull, Brooke J; Haub, Mark D; Rosenkranz, Richard R; Lawler, Thomas; Rosenkranz, Sara K

    2016-03-01

    Sedentary time is an independent risk factor for chronic diseases and mortality. It is unknown whether active adults alter their dietary and/or physical activity behaviors in response to imposed sedentary time, possibly modifying risk. The aim of this study was to determine whether imposed sedentary time would alter typical behaviors of active adults. Sixteen physically active, young adults were randomized to the no-intervention control (CON, n = 8) group or the sedentary-intervention (SIT, n = 8) group. SIT participants attended monitored sedentary sessions (8 wk, 10 h/wk). Assessments including diet and physical activity occurred at baseline, week 4, and week 9. There were no differences (P > .05) between CON and SIT groups for step counts or time spent in sedentary, light, moderate, or vigorous physical activity when comparing a week during imposed sedentary time (week 4) to baseline and week 9. At week 4, caloric intake was not different from baseline (P > .05) in either group. Caloric intake decreased significantly (P > .05) in SIT from baseline to week 9. Active adults did not alter physical activity or dietary behaviors during the imposed sedentary intervention. However, SIT reduced caloric intake from baseline to week 9, indicating a possible compensatory response to imposed sitting in active adults.

  4. The effects of an 8-week multicomponent inpatient treatment program on body composition and anaerobic fitness in overweight and obese children and adolescents

    Directory of Open Access Journals (Sweden)

    Karner-Rezek K

    2013-03-01

    Full Text Available Klaus Karner-Rezek,1 Beat Knechtle,2,3 Matthias Fenzl,4 Christian Schlegel,4 Manuela Konrad,5 Thomas Rosemann2 1Private University of the Principality of Liechtenstein, Triesen, Principality of Liechtenstein, 2Institute of General Practice and for Health Services Research, University of Zurich, Zurich, Switzerland; 3Gesundheitszentrum St Gallen, St Gallen, Switzerland; 4Swiss Olympic Medical Center, Medizinisches Zentrum Bad Ragaz, Switzerland; 5University of Applied Sciences JOANNEUM, Bad Gleichenberg, Austria Background: High intensity exercise is considered as an effective means for reducing body fat. The aims of the present study were to investigate (1 whether body mass would be lost and body composition would change and (2 whether variables of anaerobic fitness prior to the intervention period would be related to loss of body mass and changes in body composition in overweight and obese children and adolescents. Methods: A total of 28 children and adolescents (19 boys, 9 girls attended an 8-week multicomponent inpatient program. Caloric intake was based on the subject's weight and a daily energy deficit of ~500 kcal was targeted. At the beginning and at the end of the program, variables of anaerobic fitness were assessed using Wingate tests. Body composition was measured before and after the program using dual-energy X-ray absorptiometry. Results: Body mass decreased by 11.4% ± 1.6% in boys and by 11.0% ± 2.8% in girls (P < 0.001. Fat mass decreased by 23.8% ± 6.1% in boys and by 21.5% ± 5.2% in girls (P < 0.001. The decrease in fat mass was associated with the decrease in body mass in boys (r = 0.54, P = 0.017 but not in girls (P > 0.05. The decrease in body mass and the decrease in fat mass were neither associated with overall energy expenditure nor with the energy deficit in both genders (P > 0.05. Mean power in W/kg increased in the Wingate tests by 95.4% ± 109.1% in boys and by 100.0% ± 119.9% in girls (P < 0.001. Conclusions

  5. Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: A randomised controlled weight loss trial

    Directory of Open Access Journals (Sweden)

    Macdonald Ian

    2008-09-01

    Full Text Available Abstract Objective To investigate the effect of commercial weight loss programmes on macronutrient composition and micronutrient adequacy over a 2 month period. Design Adults were randomly allocated to follow the Slim Fast Plan, Weight Watchers Pure Points Programme, Dr Atkins' New Diet Revolution, or Rosemary Conley's "Eat Yourself Slim" Diet & Fitness Plan. Setting A multi-centre randomised controlled trial. Subjects 293 adults, mean age 40.3 years and a mean BMI 31.7 (range 27–38 were allocated to follow one of the four diets or control group. Subjects completed a 7-day food and activity diary at baseline (prior to randomisation and after 2 months. Diet records were analysed for nutrient composition using WinDiets (research version. Results A significant shift in the macronutrient composition of the diet with concurrent alteration of the micronutrient profile was apparent with all diets. There was no evidence to suggest micronutrient deficiency in subjects on any of the dietary regimens. However, those sub-groups with higher needs for specific micronutrients, such as folate, iron or calcium may benefit from tailored dietary advice. Conclusion The diets tested all resulted in considerable macronutrient change and resulted in an energy deficit indicating dietary compliance. Health professionals and those working in community and public health should be reassured of the nutritional adequacy of the diets tested. Trial Registration Number NCT00327821

  6. Manipulation Therapy Relieved Pain More Rapidly Than Acupuncture among Lateral Epicondylalgia (Tennis Elbow Patients: A Randomized Controlled Trial with 8-Week Follow-Up

    Directory of Open Access Journals (Sweden)

    Chung-Yuan Hsu

    2016-01-01

    Full Text Available Radial bone adjustment manipulation treatment may be effective to reduce pain rapidly in lateral epicondylalgia patients and the pathological tension in the biceps brachii muscle is highly concerned. To prove this hypothesis, we conducted a randomized controlled trial and included 35 patients with lateral epicondylalgia for more than 2 months. Either manipulation treatment (n=16 or acupuncture (n=19 was given to these patients for 2 weeks and all patients’ symptoms were followed up for 8 weeks after treatment. Both groups demonstrated changes in pain VAS score, grip strength, and DASH questionnaire. Lateral epicondylalgia patients who received manipulation treatment felt pain relief sooner than those who had acupuncture treatments during the first few treatments. However, both acupuncture and manipulation are effective, while the difference has no significance at the 8-week follow-up. The trial was registered with Current Controlled Trials ISRCTN81308551 on 5 February 2016.

  7. Efficacy of lanreotide Autogel® administered every 4–8 weeks in patients with acromegaly previously responsive to lanreotide microparticles 30 mg: a phase III trial

    OpenAIRE

    Lucas, T; Astorga, R; ,

    2006-01-01

    Objective and design Depot somatostatin analogues are well accepted as either adjuvant or primary therapy for acromegaly, and their long dosage intervals facilitate adherence to treatment. Our objective was to evaluate whether lanreotide Autogel® 120 mg, every 4–8 weeks, was as effective in controlling acromegaly as lanreotide microparticles 30 mg, every 1–2 weeks. Patients design and measurements Patients who had used lanreotide microparticles 30 mg, ≥ 2 months prestudy, and had responded to...

  8. 32 CFR 37.655 - Must I specify the frequency of IPAs' periodic audits of for-profit participants?

    Science.gov (United States)

    2010-07-01

    ..., when the participant has its IPA do its next financial statement audit, unless the participant already... audits of for-profit participants? 37.655 Section 37.655 National Defense Department of Defense OFFICE OF... Terms Affecting Participants' Financial, Property, and Purchasing Systems Financial Matters §...

  9. Perceived Participation, Experiences from Persons with Spinal Cord Injury in Their Transition Period from Hospital to Home

    Science.gov (United States)

    Van de Velde, Dominique

    2010-01-01

    It is suggested that participation should be achieved at the end of the rehabilitation process. However, there is a lack of consensus on the definition, the conceptualization and the measurement of participation. This study aims to add to the existing body of knowledge of participation by exploring the "person perceived participation" in…

  10. Diurnal Glycemic Patterns during an 8-Week Open-Label Proof-of-Concept Trial of Empagliflozin in Type 1 Diabetes.

    Directory of Open Access Journals (Sweden)

    Bruce A Perkins

    Full Text Available We recently reported improved glycemic control with reduced insulin dose in subjects with type 1 diabetes treated with the sodium glucose co-transporter-2 inhibitor empagliflozin. To further characterize the effects, we analyzed diurnal glycemic patterns by continuous glucose monitoring (CGM.In an 8-week single-arm open-label pilot study of empagliflozin, we compared ambulatory glucose profiles produced from CGM data during 2-week intervals in a placebo run-in baseline period, end-of-treatment, and post-treatment. Change in glycemic exposure was evaluated by area under the median curve according to time of day (AUCTOTAL 12:00am-11:55pm; AUCDAY 7:05am-10:55pm, AUCNIGHT 11:00pm-7:00am, as well as glycemic variability, glycemic stability and time-in-target (≥70 to ≤140mg/dL.The 40 patients (26 on insulin pump were aged 24±5 years and BMI 24.5±3.2 kg/m2. Consistent with the observed HbA1c decrease (8.0±0.9% to 7.6±0.9%, p<0.0001, normalized AUCTOTAL CGM decreased from 153.7±25.4 to 149.0±30.2mg/dL∙h at end-of-treatment (p = 0.31, and significantly increased post-treatment (164.1±29.5mg/dL∙h, p = 0.02. The numerical decrease in normalized AUCNIGHT (152.0±36.6 to 141.9±34.4mg/dL∙h, p = 0.13 exceeded AUCDAY (154.5±24.5 to 152.6±30.4mg/dL∙h, p = 0.65. Trends toward lower glycemic variability (83.1±18.9 to 75.6±28.6mg/dL, p = 0.06 and little change in glycemic stability (10.8±3.6 to 10.3±4.5mg/dL/h, p = 0.51 were observed. When empagliflozin was discontinued, these worsened relative to baseline (89.3±19.3mg/dL, p = 0.04 and 11.8±3.7mg/dL/hr, p = 0.08. Time-in-target numerically increased (40.2±11.9 to 43.1±13.5%, p = 0.69 at end-of-treatment but reversed post-treatment. Findings were similar on stratification of pump and MDI subjects.We observed that empagliflozin was associated with patterns of improved nighttime glycemia more prominent than daytime.Clinicaltrials.gov NCT01392560.

  11. The Effect of 8 Weeks of HIT Workouts Plasma Levels of TNF-a, IL-6 and Lipid Profile in Overweight Children

    Directory of Open Access Journals (Sweden)

    Abdolrezareza Kazemi

    2016-03-01

    Full Text Available Introduction: The prevalence of obesity among children and adolescents around the world alarmingly are increasing. Regular exercise can reduce fat tissue and improve body composition. The aim of this study was the effect of the high intensity interval training (HIT on plasma levels of TNF-a, IL-6 and lipid profile in overweight children. Methods: The present study was semi experimental research that performed in Tehran at 2014 year.  In this study, 32 overweight students 8 to 11 divided in the experimental (n=16 and control (n=16 group. High intensity interval training including 30 seconds with maximum speed and 5.1 minutes rest was performed for 8 weeks and 3 sessions per week. The six HIT workouts in the first week increased to 10 to last week. Blood samples were collected from venous blood of right hand 48 hours last session. ANCOVA test performed for compared of variable mean (α=0.005. Results: The results of the present study showed that 8 weeks HIT significantly reduced level of IL-6 (P=0.001, TNF-a (P=0.001 and lipid profile. On the other hand, there was insignificantly change in TG (P=0.777, LDL (P=0.071 and HDL (P=0.693. Conclusion: The findings of this study showed that 8 weeks HIT reduces the plasma level of TNF-a and IL-6. Therefore, perform of high intensity interval training with observed necessaryw55 caution in obese children can have positive effects.

  12. Effect of comorbid tics on a clinically meaningful response to 8-week open-label trial of fluoxetine in obsessive compulsive disorder.

    Science.gov (United States)

    Husted, David S; Shapira, Nathan A; Murphy, Tanya K; Mann, Giselle D; Ward, Herbert E; Goodman, Wayne K

    2007-01-01

    Currently, there are limited published data evaluating the effects of tics on serotonin reuptake inhibitor (SRI) monotherapy responses in treating obsessive-compulsive disorder (OCD). One retrospective case-controlled analysis of OCD patients treated with SRI monotherapy showed lesser improvement in OCD symptoms in patients with tics than those without. However, more recently there were preliminary reports of OCD subjects treated with SRI monotherapy which did not demonstrate poorer response in subjects with tics or Tourette's Syndrome (TS). The specific aim of this study was to investigate whether the presence of comorbid chronic tics affected "clinically meaningful improvement" [McDougle, C.J., Goodman, W.K., Leckman, J.F., Barr, L.C., Heninger, G.R., Price, L.H., 1993. The efficacy of fluvoxamine in obsessive-compulsive disorder: effects of comorbid chronic tic disorder. Journal of Clinical Psychopharmacology 13, 354-358] of OCD in an 8-week open-label trial of fluoxetine monotherapy. Seventy-four adult subjects (13 patients with comorbid chronic tics and 61 patients without tics) with a primary DSM-IV OCD diagnosis were treated with up to 40mg fluoxetine for 8 weeks and had at least one post-baseline evaluation. The results indicate that there was a significant response by time in both fluoxetine-with-tic subjects and fluoxetine-without-tic subjects. Additionally, there were 3 (23.0%) OCD subjects with tics who had clinically meaningful improvement versus 16 (26.2%) OCD subjects without tics that demonstrated similar levels of improvement. These findings indicate that OCD patients with or without chronic tic disorders did not have a differential response to an 8-week open-label trial of fluoxetine. Limitations include the relatively low number of tic subjects and the open-label nature of the study. Additional data are needed on how comorbid tics may affect SRI treatment response in OCD.

  13. Efficacy of lanreotide Autogel® administered every 4–8 weeks in patients with acromegaly previously responsive to lanreotide microparticles 30 mg: a phase III trial

    Science.gov (United States)

    Lucas, T; Astorga, R

    2006-01-01

    Objective and design Depot somatostatin analogues are well accepted as either adjuvant or primary therapy for acromegaly, and their long dosage intervals facilitate adherence to treatment. Our objective was to evaluate whether lanreotide Autogel® 120 mg, every 4–8 weeks, was as effective in controlling acromegaly as lanreotide microparticles 30 mg, every 1–2 weeks. Patients design and measurements Patients who had used lanreotide microparticles 30 mg, ≥ 2 months prestudy, and had responded to treatment were recruited to this open, prospective, multicentre phase III trial. Three to five injections of lanreotide Autogel® 120 mg were administered. Lanreotide Autogel® 120 mg was injected every 4, 6 or 8 weeks in patients previously receiving lanreotide microparticles every 7, 10 or 14 days, respectively. GH and insulin-like growth factor (IGF)-1 levels were assessed one dosing interval after the final injections. Results Ninety-eight patients were enrolled and 93 completed. Steady-state GH concentrations demonstrated similar efficacy between the formulations (upper 95% confidence interval of the quotient, 77·7%). Mean (SE) GH levels were lower with lanreotide Autogel® than with lanreotide microparticles (3·8 (0·5) vs 4·3 (0·5) ng/ml; P < 0·001). GH levels < 2·5 ng/ml were observed in 54% and 46% of patients; 40% and 35% having GH < 2·5 ng/ml and normalized IGF-1 with lanreotide Autogel® and microparticles, respectively. Symptoms were controlled better with lanreotide Autogel® and treatment was well accepted. Conclusions Lanreotide Autogel® 120 mg every 4–8 weeks, is at least as effective and as well tolerated in acromegaly as lanreotide microparticles 30 mg injected every 7–14 days. PMID:16918950

  14. The Effect of 8 Weeks Endurance Training on Serum Levels of IL-10 and IL-8, and White Blood Cell Count in Women with Breast Cancer

    Directory of Open Access Journals (Sweden)

    Abdolreza Kazemi

    2016-09-01

    Full Text Available Background & Objective: The regular exercise training is known as a preventive and adjuvant therapy in inflammatory diseases such as cancer. The aim of this study was to determine the effect of the aerobic training on IL-10 and IL-8 levels and the count of white blood cells (WBC in women with breast cancer. Material & Methods: The statistical society of the present study included Kerman women with breast cancer. Forty patients with breast cancer were randomly divided into two groups: exercise (n = 20 and control (n = 20. The exercise group performed the endurance training for 8 weeks with the intensity between 40 to 55 percent of the target heart rate. Twenty four hours before the first session and 48 hours after the last session of the exercise protocol, blood samples were taken from both groups and then IL-10 and IL-8 levels in serum were measured by ELISA via a Boster kit. Results: The results of the present study showed that 8 weeks of the endurance exercise training did not significantly increase the IL-10 (P=0.113 serum level, but increased the WBC count (p=0.019 and decreased the serum level of IL-8 (p=0.03 significantly. Conclusion: According to the results of the present study, regular endurance training via decreasing the inflammatory factors can be considered as an effective factor along with other therapies in improving breast cancer.

  15. Motivational Factors Underlying Problem Solving: Comparing Wolf and Dog Puppies' Explorative and Neophobic Behaviors at 5, 6, and 8 Weeks of Age

    Science.gov (United States)

    Marshall-Pescini, Sarah; Virányi, Zsófia; Kubinyi, Enikő; Range, Friederike

    2017-01-01

    Background: Wolves have been shown to be better in independent problem-solving tasks than dogs, however it is unclear whether cognitive or motivational factors underlie such differences. In a number of species problem solving has been linked to both persistence in exploration and neophobia, suggesting both these aspects may underlie dog-wolf differences in problem solving. Indeed adult wolves have been shown to be more likely to approach a novel object and more persistent in their investigation of it, but also slower in making contact with it and more fearful of it than dogs. Methods: In the current study we investigated potential differences in equally-raised dogs' and wolves' explorative and neophobic behaviors in a novel environment and with novel objects at 5, 6, and 8 weeks of age. Results: Results showed that wolves were more persistent in exploring both the environment and the objects than dogs, and this was the case at all ages. There were no differences in the frequency of fear-related behaviors and time spent in proximity to humans. Stress-related behaviors were similarly expressed at 5 and 6 weeks, although wolves showed a higher frequency of such behaviors at 8 weeks. Discussion: Overall, results with puppies confirm those with adult animals: wolves appear to be more explorative than dogs. Such motivational differences need to be taken into account when comparing dogs and wolves in cognitive tasks. PMID:28232814

  16. A multi-center, prospective, open-label, 8-week study of certoparin for anticoagulation during maintenance hemodialysis – the membrane study

    Directory of Open Access Journals (Sweden)

    Dorsch Oliver

    2012-06-01

    Full Text Available Abstract Background Adequate anticoagulation is prerequisite for effective hemodialysis to prevent clotting in the extracorporeal circuit. We aimed providing first data on the efficacy and safety of the low-molecular-weight heparin certoparin in this setting. Methods Multicenter, open-label, 8-week trial. Patients received a single dose of 3,000 IU certoparin i.v. with additional titration steps of 600 IU and/or continuous infusion if necessary. Results 120 patients were screened, 109 enrolled (median age 71; range 26–90 years and 106 available for efficacy analyses. The percentage of unsatisfactory dialysis results at 8 weeks due to clotting or bleeding, was 1.9% (n = 2/106; 95% confidence interval [CI] 0.23–6.65%; no major bleeding. 1.9% had moderate/severe clotting in the lines/bubble catcher and 2.8% in the dialyser at week 8. 15.7 ± 14.3% of the dialysis filters’ visual surface area was showing redness. In subgroups of patients receiving median doses of 3000 ± 0, 3000 (2400–6000 and 4200 (3000–6600 IU, plasma aXa levels at baseline, 4 and 8 weeks were 0.24 [95%CI 0.21–0.27], 0.33 [0.27–0.40] and 0.38 [0.33–0.45] aXa IU/ml at 2 h. C48h was 0.01 [0.01–0.02] aXa IU at all visits. At baseline and 4 weeks AUC0-48h was 2.66 [2.19–3.24] and 3.66 [3.00–4.45] aXa IU*h/ml. In 3.0% of dialyses (n = 83/2724 prolonged fistula compression times were documented. Eight patients (7.34% had at least one episode of minor bleeding. 4 85.3% of patients had any adverse event, 9.2% were serious without suspected drug relation; and in 32 patients a drug-relation was suspected. Conclusions Certoparin appears effective and safe for anticoagulation in patients undergoing maintenance hemodialysis.

  17. Effects of trans- and n-3 unsaturated fatty acids on cardiovascular risk markers in healthy males. An 8 weeks dietary intervention study

    DEFF Research Database (Denmark)

    Dyerberg, J; Eskesen, D C; Andersen, P W

    2004-01-01

    BACKGROUND: Studies of long-term intake of industrially produced trans fatty acids (TFA) and n-3 polyunsaturated fatty acids (PUFA) suggest opposite effects on cardiovascular disease risk. Common mechanisms of action are probable. OBJECTIVE: To examine the effects on cardiovascular risk markers...... of dietary enrichment with TFA or n-3 PUFA. DESIGN: Randomized, double-blind, parallel intervention trial. SETTING: Department of Human Nutrition, The Royal Veterinary and Agricultural University. SUBJECTS: In all, 87 healthy males included, 79 completed. INTERVENTION: Subjects were randomly assigned to 8...... weeks of a daily intake of 33 g of experimental fats from either partially hydrogenated soy oil containing 20 g of TFA, 12 g of fish oil with approximately 4 g of n-3 PUFA and 21 g of control fat, or 33 g of control fat. The experimental fats were incorporated into bakery products. Plasma lipids, blood...

  18. Reduction of abdominal fat accumulation in rats by 8-week ingestion of a newly developed sweetener made from high fructose corn syrup.

    Science.gov (United States)

    Iida, Tetsuo; Yamada, Takako; Hayashi, Noriko; Okuma, Kazuhiro; Izumori, Ken; Ishii, Reika; Matsuo, Tatsuhiro

    2013-06-01

    Many studies have shown that ingestion of high-fructose corn syrup (HFCS) may cause an increase in body weight and abdominal fat. We recently developed a new sweetener containing rare sugars (rare sugar syrup; RSS) by slight isomerization of HFCS. Here, the functional effects of RSS on body weight and abdominal fat, and biochemical parameters in Wistar rats were examined. Rats (n=30) were randomly divided into three groups and maintained for 8-weeks on starch, starch+HFCS (50:50), and starch+RSS (50:50) diets. Rats in the Starch and HFCS groups gained significantly more body weight and abdominal fat than the RSS group. Fasting serum insulin in the RSS group was significantly lower than in the Starch and HFCS groups, although serum glucose in the HFCS and RSS groups was significantly lower than that in the Starch group. Thus, the substitution of HFCS with RSS prevents obesity induced by the consumption of HFCS.

  19. A Prospective Study of Serotonin and Norepinephrine Transporter Genes and the Response to Desvenlafaxine Over 8 Weeks in Major Depressive Disorder.

    Science.gov (United States)

    Ng, C H; Bousman, C; Smith, D J; Dowling, N; Byron, K; King, J; Sarris, J

    2016-09-01

    No studies to date have evaluated SLC6A2 and SLC6A4 genetic polymorphisms influencing antidepressant response to desvenlafaxine. We conducted an 8-week, open-label, prospective pilot study in 35 patients with major depressive disorder to assess the effects of genetic variations in SLC6A2 and SLC6A4 on both efficacy and side effect profile of desvenlafaxine. Results revealed that homozygotes for the SLC6A4 HTTLPR S allele showed a 33% HDRS reduction compared to a 58% reduction for L allele carriers (p=0.037). No results survived adjustments for covariates or multiple comparisons. While these results need to be interpreted cautiously, they provide preliminary support for the SLC6A4 HTTLPR polymorphism as potential modifier of desvenlafaxine efficacy. © Georg Thieme Verlag KG Stuttgart · New York.

  20. Efficacy and Safety of Extended-Release Quetiapine Fumarate in Youth with Bipolar Depression: An 8 Week, Double-Blind, Placebo-Controlled Trial

    Science.gov (United States)

    Pathak, Sanjeev; Earley, Willie R; Liu, Sherry; DelBello, Melissa P

    2014-01-01

    Abstract Objective: Quetiapine is an atypical antipsychotic with demonstrated efficacy in the treatment of adolescent schizophrenia and pediatric bipolar mania. Large, placebo-controlled studies of interventions in pediatric bipolar depression are lacking. The current study investigated the efficacy and safety of quetiapine extended-release (XR) in patients 10–17 years of age, with acute bipolar depression. Methods: This multicenter, double-blind, randomized, placebo-controlled study investigated quetiapine XR (dose range, 150–300 mg/day) in pediatric outpatients with an American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision (DSM-IV-TR) diagnosis of bipolar I or bipolar II disorder (current or most recent episode depressed) treated for up to 8 weeks (ClinicalTrials.gov identifier: NCT00811473). The primary study outcome was mean change in Children's Depression Rating Scale–Revised (CDRS-R) total score. Secondary efficacy outcomes included CDRS-R-based response and remission rates. Results: Of 193 patients randomized to treatment, 144 patients completed the study (75.3% of quetiapine XR group [n=70]; 74.0% of placebo group [n=74]). Least squares mean changes in CDRS-R total score at week 8 were: −29.6 (SE, 1.65) with quetiapine XR and −27.3 (SE, 1.60) with placebo, a between-treatment group difference of −2.29 (SE, 1.99; 95% CI, −6.22, 1.65; p=0.25; mixed-model for repeated measures analysis). Rates of response and remission did not differ significantly between treatment groups. The safety profile of quetiapine XR was broadly consistent with the profile reported previously in adult studies of quetiapine XR and pediatric studies of quetiapine immediate-release (IR). Potentially clinically significant elevations in clinical chemistry values included triglycerides (9.3%, quetiapine XR; 1.4%, placebo group) and thyroid stimulating hormone (4.7%, quetiapine XR; 0%, placebo group). An adverse event

  1. Confirmation of efficacy in providing relief from the pain of dentin hypersensitivity of an anhydrous dentifrice containing 0.454% with or without stannous fluoride in an 8-week randomized clinical trial.

    Science.gov (United States)

    Parkinson, Charles R; Jeffery, Peter; Milleman, Jeffery L; Milleman, Kimberly R; Mason, Stephen

    2015-08-01

    To compare the efficacy of an anhydrous dentifrice containing 0.454% w/w stannous fluoride and a negative control dentifrice containing 1,000 ppm fluoride, as sodium monofluorophosphate, at reducing dentin hypersensitivity over 8 weeks with twice-daily brushing. This was a randomized, examiner-blind, parallel, two treatment group, stratified (by maximum baseline Schiff sensitivity score), 8-week clinical study carried out at a single site in 119 healthy subjects with at least two sensitive teeth, who met all study criteria at the screening and baseline visits. Clinical assessments of sensitivity to evaporative (air) [with Schiff sensitivity score and visual analogue scale (VAS)] and tactile (Yeaple probe) stimuli were employed to compare the efficacy of the test dentifrice containing 0.454% w/w stannous fluoride to the negative control dentifrice at reducing sensitivity after 4 and 8 weeks treatment. Of the 119 subjects randomized to study treatment, 113 completed the study. At 4 and 8 weeks, between treatment analyses found the test dentifrice to be significantly better than the negative control dentifrice in relieving dentin hypersensitivity for all measures (Schiff: P < 0.0001 at 4 and 8 weeks; VAS score: P = 0.0003 at 4 weeks, P < 0.0001 at 8 weeks; tactile threshold: P = 0.0138 at 4 weeks, P < 0.0001 at 8 weeks).

  2. The effects of an 8-week computer-based brain training programme on cognitive functioning, QoL and self-efficacy after stroke.

    Science.gov (United States)

    Wentink, M M; Berger, M A M; de Kloet, A J; Meesters, J; Band, G P H; Wolterbeek, R; Goossens, P H; Vliet Vlieland, T P M

    2016-10-01

    Cognitive impairment after stroke has a direct impact on daily functioning and quality of life (QoL) of patients and is associated with higher mortality and healthcare costs. The aim of this study was to determine the effect of a computer-based brain training programme on cognitive functioning, QoL and self-efficacy compared to a control condition in stroke patients. Stroke patients with self-perceived cognitive impairment were randomly allocated to the intervention or control group. The intervention consisted of an 8-week brain training programme (Lumosity Inc.®). The control group received general information about the brain weekly. Assessments consisted of a set of neuropsychological tests and questionnaires. In addition, adherence with trained computer tasks was recorded. No effect of the training was found on cognitive functioning, QoL or self-efficacy when compared to the control condition, except for very limited effects on working memory and speed. This study found very limited effects on neuropsychological tests that were closely related to trained computer tasks, but no transfers to other tests or self-perceived cognitive failures, QoL or self-efficacy. These findings warrant the need for further research into the value of computer-based brain training to improve cognitive functioning in the chronic phase after stroke.

  3. Effect of 8 Weeks of Overfeeding on Ectopic Fat Deposition and Insulin Sensitivity: Testing the “Adipose Tissue Expandability” Hypothesis

    Science.gov (United States)

    Johannsen, Darcy L.; Tchoukalova, Yourka; Tam, Charmaine S.; Covington, Jeffrey D.; Xie, Wenting; Schwarz, Jean-Marc; Bajpeyi, Sudip

    2014-01-01

    OBJECTIVE The presence of large subcutaneous adipocytes in obesity has been proposed to be linked with insulin resistance and type 2 diabetes through the “adipose tissue expandability” hypothesis, which holds that large adipocytes have a limited capacity for expansion, forcing lipids to be stored in nonadipose ectopic depots (skeletal muscle, liver), where they interfere with insulin signaling. This hypothesis has, however, been largely formulated by cross-sectional findings and to date has not been prospectively demonstrated in the development of insulin resistance in humans. RESEARCH DESIGN AND METHODS Twenty-nine men (26.8 ± 5.4 years old; BMI 25.5 ± 2.3 kg/m2) were fed 40% more than their baseline requirement for 8 weeks. Before and after overfeeding, insulin sensitivity was determined using a two-step hyperinsulinemic-euglycemic clamp. Intrahepatic lipid (IHL) and intramyocellular lipid (IMCL) were measured by 1H-MRS and abdominal fat by MRI. Subcutaneous abdominal adipose and skeletal muscle tissues were collected to measure adipocyte size and markers of tissue inflammation. RESULTS Subjects gained 7.6 ± 2.1 kg (55% fat) and insulin sensitivity decreased 18% (P fat cells at baseline had a greater decrease in insulin sensitivity, which was linked with upregulated skeletal muscle tissue inflammation. CONCLUSIONS In experimental substantial weight gain, the presence of larger adipocytes did not promote ectopic lipid accumulation. In contrast, smaller fat cells were associated with a worsened metabolic response to overfeeding. PMID:25011943

  4. Conjugated linoleic acid supplementation for 8 weeks does not affect body composition, lipid profile, or safety biomarkers in overweight, hyperlipidemic men.

    Science.gov (United States)

    Joseph, Shama V; Jacques, Hélène; Plourde, Mélanie; Mitchell, Patricia L; McLeod, Roger S; Jones, Peter J H

    2011-07-01

    The usefulness of conjugated linoleic acid (CLA) as a nutraceutical remains ambiguous. Our objective was, therefore, to investigate the effect of CLA on body composition, blood lipids, and safety biomarkers in overweight, hyperlipidemic men. A double-blinded, 3-phase crossover trial was conducted in overweight (BMI ≥ 25 kg/m(2)), borderline hypercholesterolemic [LDL-cholesterol (C) ≥ 2.5 mmol/L] men aged 18-60 y. During three 8-wk phases, each separated by a 4-wk washout period, 27 participants consumed under supervision in random order 3.5 g/d of safflower oil (control), a 50:50 mixture of trans 10, cis 12 and cis 9, trans 11 (c9, t11) CLA:Clarinol G-80, and c9, t11 isomer:c9, t11 CLA. At baseline and endpoint of each phase, body weight, body fat mass, and lean body mass were measured by DXA. Blood lipid profiles and safety biomarkers, including insulin sensitivity, blood concentrations of adiponectin, and inflammatory (high sensitive-C-reactive protein, TNFα, and IL-6) and oxidative (oxidized-LDL) molecules, were measured. The effect of CLA consumption on fatty acid oxidation was also assessed. Compared with the control treatment, the CLA treatments did not affect changes in body weight, body composition, or blood lipids. In addition, CLA did not affect the β-oxidation rate of fatty acids or induce significant alterations in the safety markers tested. In conclusion, although no detrimental effects were caused by supplementation, these results do not confirm a role for CLA in either body weight or blood lipid regulation in humans.

  5. Butylated hydroxytoluene can protect polyunsaturated fatty acids in dried blood spots from degradation for up to 8 weeks at room temperature.

    Science.gov (United States)

    Metherel, Adam H; Hogg, Ryan C; Buzikievich, Lindy M; Stark, Ken D

    2013-02-20

    Dried blood spots (DBS) from fingertip prick blood can enable high throughput fatty acid profiling but may be prone to lipid peroxidation during storage. The use of butylated hydroxytoluene (BHT) on chromatography paper can prevent polyunsaturated fatty acid (PUFA) loss but examinations on the length of storage times possible are not comprehensive. In the first study, venous whole blood was saturated on paper strips pre-soaked with 0, 2.5 or 5.0 mg/mL BHT and exposed to air for up to 28 days. In a second study, the effect of sealing DBS on 5.0 mg/mL BHT-soaked chromatography strips in capped test tubes or vacuum sealed polypropylene bags with and without nitrogen purging was examined over eight weeks. The fatty acid composition of the DBS were determined by gas chromatography and the effect of sample storage on omega-3 biomarkers were examined. PUFA and omega-3 biomarkers in DBS stored without BHT were dramatically reduced by day 3. In general, BHT delayed decreases in eicosapentaenoic + docosahexaenoic acid from baseline (3.2 ± 0.2 wt%) to 28 days (2.6 ± 0.03 wt%) of storage. In the % n-3 highly unsaturated fatty acids (HUFA) in total HUFA biomarker, BHT was more effective at preventing changes, particularly with 5.0 mg/mL BHT where no differences were detected up to 28 days. Sealed storage with BHT tended to increase the stability of the PUFA in DBS and nitrogen purging did not appear to provide additional benefits. The % n-3 HUFA in total HUFA biomarker also appeared to be more stable in the sealed storage study. The storage of DBS in sealed containers with BHT may prevent PUFA degradation for up to 8 weeks. The % n-3 HUFA in total HUFA biomarker appears to provide a more consistent assessment of omega-3 status throughout storage as compared with other omega-3 blood biomarkers.

  6. The Participation Banking As A Distinctive Method And The Its Growing In The Turkish Finance Market-Period: 2007-2013

    Directory of Open Access Journals (Sweden)

    Ferhat Sayım

    2015-02-01

    Full Text Available Financial systems and companies has become the most important reason in the weakness of world economic system. The formation and development process of the financial structure also constitutes the infrastructure of the world economic system. The path of the financial system and development has led to discuss with the financial crisis in 2008-2011. One of the argument topic in order to reduce problems caused by the conventional banking system is alternative financing systems. In Turkey, the corporations based on profit share system which are named participation based banking attention, if the alternative banking systems are considered. These banks which settle on different principles in the risk distribution of the portfolio acquired are analyzed more nowadays. Participation based banks are placed in almost every regulation related to banking terms and get their legal infrastructure more stable in the banking legislation of Turkey.This study is a 2007-2013 part of research series. We try to find out the place and the importance of participation based banking with the various sub-headings especially in Turkey. We examine the comparative review 2007-2013 data of participation banks which Total Assets, Equity Net Profit, Collected Turkish Currency and Foreign Currency Funds and Bank Loan Funds, figures for the four participation banks in Turkey. We are comparing the total figures with deposit banks for the same period.One of our primary aim in this essay, to study in the framework of the alternatives of the financial companies and options. These options could be stated as a vibrant and viable well established choice as a non-western model- different from the classical western interest based leading banking system in the globe. Moreover, that participation banking systems’ grow and increase with its resourceful bulk of transactions and shares within the financial market. In addition, we intended to delineate the basic functioning structures, rules

  7. Impact of Periodic Presumptive Treatment for Bacterial Vaginosis on the Vaginal Microbiome among Women Participating in the Preventing Vaginal Infections Trial.

    Science.gov (United States)

    Balkus, Jennifer E; Srinivasan, Sujatha; Anzala, Omu; Kimani, Joshua; Andac, Chloe; Schwebke, Jane; Fredricks, David N; McClelland, R Scott

    2017-03-01

    Evidence suggests that specific vaginal bacteria associated with bacterial vaginosis (BV) may increase the risk of adverse health outcomes in women. Among women participating in a randomized, double-blinded trial, we assessed the effect of periodic presumptive treatment (PPT) on detection of select vaginal bacteria. High-risk women from the United States and Kenya with a recent vaginal infection received intravaginal metronidazole 750 mg plus miconazole 200 mg or placebo for 5 consecutive nights each month for 12 months. Vaginal fluid specimens were collected via polyester/polyethylene terephthalate swabs every other month and tested for bacteria, using quantitative polymerase chain reaction (PCR) assays targeting the 16S ribosomal RNA gene. The effect of PPT on bacterium detection was assessed among all participants and stratified by country. Of 234 women enrolled, 221 had specimens available for analysis. The proportion of follow-up visits with detectable quantities was lower in the PPT arm versus the placebo arm for the following bacteria: BVAB1, BVAB2, Atopobium vaginae, Leptotrichia/Sneathia, and Megasphaera. The magnitude of reductions was greater among Kenyan participants as compared to US participants. Use of monthly PPT for 1 year reduced colonization with several bacteria strongly associated with BV. The role of PPT to improve vaginal health should be considered, and efforts to improve the impact of PPT regimens are warranted.

  8. Add-on Pregnenolone with L-Theanine to Antipsychotic Therapy Relieves Negative and Anxiety Symptoms of Schizophrenia: An 8-week, randomized, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Kardashev, Adasa; Ratner, Yael; Ritsner, Michael S

    2015-07-28

    Pregnenolone (PREG) and L-Theanine (LT) have shown ameliorative effects on various schizophrenia symptoms. This is the first study to evaluate the efficacy and safety of augmentation of antipsychotic treatment among patients with chronic schizophrenia or schizoaffective disorder with PREG - LT. Double-blind, placebo-controlled trial of PREG - LT or placebo augmentation was conducted for 8 weeks with 40 chronic DSM-IV schizophrenia and schizoaffective disorder patients with suboptimal response to antipsychotics. Oral PREG (50 mg/day) with LT (400 mg/day) or placebo were added to a stable regimen of antipsychotic medication from March 2011 to October 2013. The participants were rated using the Scale for the Assessment of Negative Symptoms (SANS), Hamilton Scale for Anxiety (HAM-A), and Positive and Negative Syndrome Scale (PANSS) scales bi-weekly. The decrease of SANS and HAM-A scores were the co-primary outcomes. Secondary outcomes included assessments of general functioning and side effects. Negative symptoms such as blunted affect, alogia, and anhedonia (SANS) were found to be significantly improved, with moderate effect sizes among patients who received PREG-LT, in comparison with the placebo group. Add-on PREG-LT also significantly associated with a reduction of anxiety scores such as anxious mood, tension, and cardiovascular symptoms (HAM-A), and elevation of general functioning (GAF). Positive symptoms, antipsychotic agents, concomitant drugs, and illness duration did not associate significantly with effect of PREG-LT augmentation. PREG-LT was well-tolerated. Pregnenolone with L-Theanine augmentation may offer a new therapeutic strategy for treatment of negative and anxiety symptoms in schizophrenia and schizoaffective disorder. Further studies are warranted. clinicaltrials.gov Identifier: NCT01831986.

  9. Evaluation of efficacy and safety of Lactobacillus rhamnosus in children aged 4-48 months with atopic dermatitis: An 8-week, double-blind, randomized, placebo-controlled study.

    Science.gov (United States)

    Wu, Yi-Jie; Wu, Wei-Fong; Hung, Chia-Wei; Ku, Ming-Shiu; Liao, Pei-Fen; Sun, Hai-Lun; Lu, Ko-Hsiu; Sheu, Ji-Nan; Lue, Ko-Huang

    2015-11-27

    The main objective of this study was to evaluate the efficacy and safety of Lactobacillus rhamnosus in children aged 4-48 months with atopic dermatitis. The design of this study was a two-center, double-blind, randomized, and placebo-controlled study with two parallel groups to evaluate the efficacy and safety profile of L. rhamnosus in children aged 4-48 months with atopic dermatitis diagnosed using Hanifin and Rajka criteria and with a Scoring of Atopic Dermatitis (SCORAD) ≥ 15 at enrollment. The duration of this study was 8 weeks with a total of five visits. The enrolled patients were allocated into either a treatment group (one ComProbi capsule containing L. rhamnosus a day) or a control group (one capsule of placebo a day) at a ratio of 1:1. The primary endpoint was to compare the mean change from baseline in SCORAD after 8 weeks of treatment. The other secondary end points were to compare the following: the mean changes from baseline in SCORAD at postbaseline visits, the frequency and total amount of the use of corticosteroids during the 8-week treatment, the frequency of atopic dermatitis and the symptom-free duration, the mean changes from baseline in Infant Dermatitis Quality of Life Questionnaire at Week 4 and Week 8, and the mean changes from baseline in the Dermatitis Family Impact Questionnaire at Week 4 and Week 8. The mean changes in SCORAD from baseline at Week 8 was -21.69 ± 16.56 in the L. rhamnosus group and -12.35 ± 12.82 in the placebo group for the intent-to-treat population (p = 0.014). For the per-protocol population, the mean change of SCORAD from baseline was -23.20 ± 15.24 in the L. rhamnosus group and -12.35 ± 12.82 in the placebo group (p = 0.003). Significant differences were demonstrated between groups at Week 8 in intensity in the intent-to-treat population and per-protocol population. Throughout the period, the amount of topical corticosteroids used showed no difference between groups. No significant

  10. Sustained biochemical control in patients with acromegaly treated with lanreotide depot 120 mg administered every 4 weeks, or an extended dosing interval of 6 or 8 weeks: a pharmacokinetic approach

    Directory of Open Access Journals (Sweden)

    Gomez-Panzani E

    2012-12-01

    Full Text Available Edda Gomez-Panzani,1 Stephen Chang,1 Joaquim Ramis,2 Michelle M Landolfi,1 Bert Bakker11Ipsen Biopharmaceuticals, Inc, Basking Ridge, New Jersey, USA; 2Ipsen Innovation SAS, Pharmacokinetic and Drug Metabolism, Les Ulis, FranceObjective: Lanreotide depot is a long-acting somatostatin receptor ligand injected deep subcutaneously every 4 weeks for the treatment of acromegaly. The aim of the presented studies was to establish whether lanreotide depot, administered to patients with acromegaly at an extended dosing interval of 6 or 8 weeks, is effective in maintaining appropriate serum growth hormone (GH and insulin-like growth factor-1 (IGF-1 levels, with acceptable tolerability.Methods: Two studies were conducted. Study B1 compared lanreotide depot 120 mg (every 4, 6, or 8 weeks with lanreotide microparticle formulation 30 mg (every 7, 10, or 14 days in 98 patients who had a GH level of ≤2.5 ng/mL and normalized IGF-1. Study B2 evaluated lanreotide depot 120 mg administered to 64 patients every 8 weeks, after which the dosing interval was adjusted based on GH levels.Results: Mean lanreotide trough serum concentrations at steady state for all dosing intervals were >1.13 ng/mL, shown to achieve a GH level of ≤2.5 ng/mL. In Study B1, following treatment with lanreotide depot given every 6 or 8 weeks, 87.5% and 93.9% of patients, respectively, had normalized GH, whereas 83.3% and 88.5% of patients, respectively, had both normalized GH and IGF-1. In Study B2, 88.9% had normalized GH and 42.9% of patients had normalized GH and IGF-1 following lanreotide depot every 8 weeks. Gastrointestinal disorders, generally mild/moderate in severity, were the most common adverse events.Conclusion: In the studies presented, lanreotide depot 120 mg every 4, 6, or 8 weeks provided effective hormonal control with acceptable safety. An extended dosing interval is a feasible approach for patients adequately controlled with lanreotide depot 60 or 90 mg every 4 weeks

  11. Oxygen utilization, carbon dioxide elimination and ventilation during recovery from supine bicycle exercise 6 to 8 weeks after acute myocardial infarction.

    Science.gov (United States)

    Sumimoto, T; Sugiura, T; Takeuchi, M; Yuasa, F; Hasegawa, T; Nakamura, S; Iwasaka, T; Inada, M

    1991-06-01

    The pattern of oxygen (O2) consumption (VO2), carbon dioxide (CO2) production (VCO2), ventilatory and metabolic responses during and in recovery from supine bicycle exercise was examined in 18 patients with recent myocardial infarction. An increase in VO2 with increasing work load was accomplished by proportional increases in both cardiac output and the arteriovenous O2 difference. During recovery, however, the arteriovenous O2 difference rapidly decreased below levels at rest, whereas VO2 and cardiac output remained elevated, indicating that VO2 during recovery further depended on relatively high cardiac output. The ratio of VCO2 to VO2 further increased after exercise, suggesting that such cardiac output contributed to the remaining high CO2 flow to the lung and therefore enhanced ventilation. Increased arterial catecholamines during exercise remained elevated for the first 5 minutes of recovery. Arterial lactate during this period continued to increase and resulted in profound metabolic acidosis, causing alveolar hyperventilation after exercise. These results suggest that during recovery from exercise, cardiopulmonary responses remain enhanced because of continuing high cardiac output, resulting in subsequent high CO2 flow to the lung and metabolic acidosis, and that this may be associated with profound fatigue or dyspnea after exercise.

  12. The Effect of 8 Weeks of Aerobic Training and Consumption of Hydro-alcoholic Extract of Nettle on Apelin and hs-CRP plasma Levels of Overweight and Obese Women

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    M Madadi Jaberi

    2016-12-01

    Full Text Available Background and aim: The use of exercise along with herbal supplements is one method proposed for controlling obesity and its complications. The aim of this study was to investigate the effect of 8 weeks aerobic training and use of hydro-alcoholic extract of nettle on levels apelin and hs-CRP plasma in overweight and obese women. Methods: The present quasi-experimental study was conducted with blind randomized clinical trial. 46 overweight and obese women (body mass index greater than 25 kilograms per square millimeter two, aged 25-45 years were selected purposefully and randomly divided into four groups of: aerobic training + hydro alcoholic extract of nettle, aerobic exercise + placebo extract of nettle and placebo. The intervention group and placebo received 8 mg of hydro alcoholic extract of nettle 8 ml of water-soluble daily for 8 weeks respectively. Aerobic exercise ergometer for 8 weeks, 3 sessions of 16 to 30 minutes with the intensity of 60-75% heart rate was reserved. In two pre and post-test after 14 hours of fasting at the same conditions, blood samples were collected. The ELISA method was use to assess levels of plasma apelin and hs-CRP d. Data obtained were analyzed using the Kolmogorov-Smirnov test, ANOVA, t-test and LSD test. Results: The results showed that the levels of hs-CRP were significantly different in comparison among the groups as well as in groups of aerobic exercise + hydro alcoholic extract of nettle, nettle and hydro-alcholic aerobic exercise + placebo significant reduction was observed (p>0.05. Conclusion: It seems that consumption of Nettle extract along with aerobic exercise through Weight loss, body fat percentage and BMI, play an effective role in control of obesity and reducing of inflammatory Apelin markers and hs-CRP in obese women

  13. Efficacy and tolerability of adding coenzyme A 400 U/d capsule to stable statin therapy for the treatment of patients with mixed dyslipidemia: an 8-week, multicenter, double-Blind, randomized, placebo-controlled study

    OpenAIRE

    Lai, Jiangtao; Wu, Bifeng; Xuan, Tianming; Liu, Zhong; Chen, Junzhu

    2014-01-01

    Background Patients with mixed hyperlipidemia usually are in need of combination therapy to achieve low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) target values for reduction of cardiovascular risk. This study investigated the efficacy and safety of adding a new hypolipidemic agent, coenzyme A (CoA) to stable statin therapy in patients with mixed hyperlipidemia. Methods In this multi-center, 8-week, double-blind study, adults who had received ≥8 weeks of stable statin thera...

  14. Sports Participation and Health during Periods of Educational Transition: A Study of 30-35-Year-Olds in North-West England

    Science.gov (United States)

    Haycock, David; Smith, Andy

    2014-01-01

    In view of the persistence of health inequalities and declines in leisure-sport participation over the life course, several quantitative investigations have explored the links between participation and other leisure activities, which have their foundations in childhood and youth, as a means of understanding adults' health behaviours. This paper…

  15. Functional and structural vascular adaptations following 8 weeks of low volume high intensity interval training in lower leg of type 2 diabetes patients and individuals at high risk of metabolic syndrome

    DEFF Research Database (Denmark)

    Madsen, Søren Møller; Thorup, Anne Cathrine Sønderstgaard; Overgaard, Kristian;

    2015-01-01

    We wished to investigate the effects of 8 weeks of low volume high intensity interval training (HIIT) on endothelial function of popliteal artery and circulating cell adhesion molecules in type 2 diabetes (T2D) patients and matched controls (CON). Methods: Over 8 weeks, non-active T2D patients...... and CONs cycled three times per week (10 × 60 sec HIIT). Pre- and post-HIIT measurements of endothelial function were conducted by applying flow-mediated dilation (FMD) along with taking venous blood samples. Results: Baseline diameter of popliteal artery increased significantly from an average of 5.53 mm.......12% to 6.58% in the CON-group (p = 0.004) and 4.84% to 5.66% in the T2D-group: (p = 0.045). The shear rate reduced significantly in both groups (CON-group: p = 0.04; T2D-group: p = 0.002). Circulating cell adhesion molecules remained unchanged (p > 0.05). Conclusion: HIIT induced an improvement...

  16. The impact of 8 weeks selected corrective exercises on neck pain, range of motion in the shoulder and neck of lifesaver women who suffering from forward head posture and myofascial pain syndrome

    Directory of Open Access Journals (Sweden)

    Melody Tabatabaei

    2017-06-01

    Full Text Available Background: The purpose of this research was studying the impact of 8 weeks selected corrective exercises on neck pain, range of motion in the shoulder and neck of lifesaver women who suffering from forward head posture and myofascial pain syndrome. Methods: The method of research is semi-experimental. The population consists of 30 lifesaver women who suffering from forward head posture and myofascial pain syndrome who they placed randomly in two groups of experimental (33±2.2 and control (33±2.5. Research plan was as the pre-test and post-test with control group. The exercise protocol was carried out by experimental groups for 8 weeks, 3 sessions per week, each session lasting 45 minutes. Studied variables include myofascial pain in the neck, shoulder and neck range of motion. The mean and standard deviation were used as descriptive statistics and in the section of inferential statistics analysis of covariance was used. Results: Results of research indicated that, the protocol on the reform exercise of neck pain (P=0.001, range of motion of shoulder joint (P=0.001 and neck range of motion (P=0.001 has significant difference. Conclusion: Therefore, lifesavers women can benefit from it as a training program to improve and prevent damage caused by head forward and myofascial pain syndrome.

  17. 32 CFR 37.645 - Must I require periodic audits, as well as award-specific audits, of for-profit participants?

    Science.gov (United States)

    2010-07-01

    ... Award Terms Affecting Participants' Financial, Property, and Purchasing Systems Financial Matters § 37... address whatever may be needed. Your inclusion in the TIA of the standard access-to-records provision...

  18. Reproducibility of Retinol Binding Protein 4 and Omentin-1 Measurements over a Four Months Period: A Reliability Study in a Cohort of 207 Apparently Healthy Participants.

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    Clemens Wittenbecher

    Full Text Available The reliability of single time point measurements of the novel adipokines retinol-binding protein 4 and omentin-1 in the blood has not been evaluated in large samples yet. The present study aimed to assess the amount of biological variation of these two adipokines within individuals. The study sample comprised 207 participants (124 women and 83 men from Potsdam (Germany and surrounding areas, with an average age of 56.5 years (SD 4.2. Blood samples were collected from each participant twice, approximately four months apart. Using enzyme linked immunosorbent assays, the concentrations of retinol-binding protein 4 and omentin-1 were determined in EDTA plasma. As indicators of reliability, intraclass correlation coefficients (ICCs were calculated from the repeated biomarker measurements. The ICCs for repeated retinol-binding protein 4 and omentin-1 measurements were 0.77 (95% CI 0.71, 0.82 and 0.83 (95% CI 0.78, 0.87, respectively, indicating for both adipokines excellent reliability. ICCs were stable across strata according to sex, age, BMI, and blood pressure. Thus, for epidemiological studies it seems reasonable to rely on concentrations of retinol-binding protein 4 and omentin-1 in samples from a single time point if repeated measurements are not available.

  19. Impact of Maternal HIV Seroconversion during Pregnancy on Early Mother to Child Transmission of HIV (MTCT Measured at 4-8 Weeks Postpartum in South Africa 2011-2012: A National Population-Based Evaluation.

    Directory of Open Access Journals (Sweden)

    Thu-Ha Dinh

    Full Text Available Mother-to-child transmission of HIV (MTCT depends on the timing of HIV infection. We estimated HIV-seroconversion during pregnancy (HSP after having a HIV-negative result antenatally, and its contribution to early MTCT in South Africa (SA.Between August 2011 and March 2012, we recruited a nationally representative sample of mother-infant pairs with infants aged 4-to-8 weeks from 578 health facilities. Data collection included mother interviews, child health-card reviews, and infant dried-blood-spots sample (iDBS. iDBS were tested for HIV antibodies and HIV-deoxyribonucleic-acid (HIV-DNA. HSP was defined as maternal self-report of an HIV-negative test during this pregnancy, no documented use of antiretroviral drugs and a matched HIV sero-positive iDBS. We used 20 imputations from a uniform distribution for time from reported antenatal HIV-negative result to delivery to estimate time of HSP. Early MTCT was defined based on detection of HIV-DNA in iDBS. Estimates were adjusted for clustering, nonresponse, and weighted by SA's 2011 live-births.Of 9802 mother-infant pairs, 2738 iDBS were HIV sero-positive, including 212 HSP, resulting in a nationally weighted estimate of 3.3% HSP (95% Confidence Interval: 2.8%-3.8%. Median time of HIV-seroconversion was 32.8weeks gestation;28.3% (19.7%- 36.9% estimated to be >36 weeks. Early MTCT was 10.7% for HSP (6.2%-16.8% vs. 2.2% (1.7%-2.8% for mothers with known HIV-positive status. Although they represent 2.2% of all mothers and 6.7% of HIV-infected mothers, HSP accounted for 26% of early MTCT. Multivariable analysis indicated the highest risk for HSP was among women who knew the baby's father was HIV-infected (adjusted-hazard ratio (aHR 4.71; 1.49-14.99, or who had been screened for tuberculosis (aHR 1.82; 1.43-2.32.HSP risk is high and contributes significantly to early MTCT. Identification of HSP by repeat-testing at 32 weeks gestation, during labor, 6 weeks postpartum, in tuberculosis-exposed women, and in

  20. Age peculiarities of reproductive morbidity in female participants of the ChNPP accident consequences clean up (according to the figures from SRU, 1988-2012 survey period).

    Science.gov (United States)

    Mayevska, I O; Buzunov, V O

    2015-12-01

    Meta: vyznachyty ta otsinyty osoblyvosti zakhvoriuvanosti statevoI systemy u zhinok uchasnyts' likvidatsiI naslidkiv avariI na ChAES 1986–1987 rr. zalezhno vid reproduktyvnogo viku na moment oprominennia ta chasu pislia opromi nennia.Materialy i metody. U statti predstavleno dani Derzhavnogo reiestru UkraIny osib, iaki postrazhdaly vnaslidok Chornobyl's'koI katastrofy. Provedeno analiz rivnia i struktury zakhvoriuvanosti statevoI systemy u 17237 zhinok uchasnyts' likvidatsiI naslidkiv avariI na ChAES 1986–1987 rr. zalezhno vid chasu perebuvannia pid ryzykom pislia oprominennia i reproduktyvnogo viku v moment oprominennia. Period monitoryngu 1988–2012 rr. Dlia vyz nachennia rivnia zakhvoriuvanosti, dovirchykh intervaliv i virogidnosti riznytsi vykorystano probnu versiiu programy OpenEpiversion 2.3.1., virogidnist' riznytsi vyznachalas' z vykorystanniam kryteriIv z score i t.Rezul'taty. Rezul'taty kogortnogo epidemiologichnogo doslidzhennia vyiavyly osoblyvosti rozvytku khvorob zhino choI statevoI systemy zalezhno vid reproduktyvnogo viku na moment oprominennia ta chasu perebuvannia pid ryzy kom pislia oprominennia. Provedeno porivnial'nyy statystychnyy analiz rivnia i struktury zakhvoriuvanosti state voI systemy za riznyy period chasu sposterezhennia.Vysnovok. Faktorom ryzyku zbil'shennia zakhvoriuvanosti na leyomiomy matky, dobroiakisni dysplaziI molochnoI zalozy, sal'pingooforyty mozhe buty oprominennia u reproduktyvnomu vitsi (18–45 r.). Mozhna prypustyty, shcho tkanyny matky ta molochnoI zalozy u zhinok, oprominenykh u reproduktyvnomu vitsi bil'sh chutlyvi na vplyv radiatsiynogo oprominennia, nizh u zhinok, iaki buly oprominenni u premenopauzi ta menopauzi.

  1. Prevalence of newborn bacterial meningitis and sepsis during the pregnancy period for public health care system participants in Salvador, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Luzia Poliana Anjos da Silva

    Full Text Available Bacterial meningitis is still a major public health threat inside developing countries. In Brazil, the Department of Public Health estimates that the prevalence of bacterial meningitis is 22 cases per 100,000 persons. During the neonatal period, the bacterial meningitis develops special characteristics that can result in hearing problems and movement loss due to neurological and psychological damages. This study had the aim to analyze the prevalence of bacterial meningitis and sepsis in newborns during the pregnancy period for those using the public health care system in Salvador-Bahia. One of the goal was to describe the risk factors of bacterial meningitis and sepsis in newborns. A second goal was to identify, based on newborn health records, the difficulties to predict issues with the hearing, neurological and psychological problems. This study has a cross-sectional design. The newborns that were included in this study had bacterial meningitis or sepsis within 0-28 days of life. They were admitted in the maternity wards between June-December 2005 at the newborn intensive unit care. We analyzed 72 reports of newborns and only 11 (17% were bacterial meningitis or sepsis newborn cases. These cases were associated to high intake of ototoxic drugs that can cause oto and nephrotoxicity, and cause serious sequels on the child development. Nervous system infection is one of the 2 major problems in clinical practice, especially during the first month after birth. During this first month, the nervous system infection develops special characteristics, which are different from regular symptoms and it requires treatment due to the increased risk to develop complications. It is strongly recommended to monitor ototoxic drugs use to prevent effects on the hearing system.

  2. Prevalence of newborn bacterial meningitis and sepsis during the pregnancy period for public health care system participants in Salvador, Bahia, Brazil.

    Science.gov (United States)

    da Silva, Luzia Poliana Anjos; Cavalheiro, Laura Giotto; Queirós, Fernanda; Nova, Camila Vila; Lucena, Rita

    2007-04-01

    Bacterial meningitis is still a major public health threat inside developing countries. In Brazil, the Department of Public Health estimates that the prevalence of bacterial meningitis is 22 cases per 100,000 persons. During the neonatal period, the bacterial meningitis develops special characteristics that can result in hearing problems and movement loss due to neurological and psychological damages. This study had the aim to analyze the prevalence of bacterial meningitis and sepsis in newborns during the pregnancy period for those using the public health care system in Salvador-Bahia. One of the goal was to describe the risk factors of bacterial meningitis and sepsis in newborns. A second goal was to identify, based on newborn health records, the difficulties to predict issues with the hearing, neurological and psychological problems. This study has a cross-sectional design. The newborns that were included in this study had bacterial meningitis or sepsis within 0-28 days of life. They were admitted in the maternity wards between June-December 2005 at the newborn intensive unit care. We analyzed 72 reports of newborns and only 11 (17%) were bacterial meningitis or sepsis newborn cases. These cases were associated to high intake of ototoxic drugs that can cause oto and nephrotoxicity, and cause serious sequels on the child development. Nervous system infection is one of the 2 major problems in clinical practice, especially during the first month after birth. During this first month, the nervous system infection develops special characteristics, which are different from regular symptoms and it requires treatment due to the increased risk to develop complications. It is strongly recommended to monitor ototoxic drugs use to prevent effects on the hearing system.

  3. Effects of vitamin D2-fortified bread v. supplementation with vitamin D2 or D3 on serum 25-hydroxyvitamin D metabolites: an 8-week randomised-controlled trial in young adult Finnish women

    DEFF Research Database (Denmark)

    Itkonen, Suvi T.; Skaffari, Essi; Saaristo, Pilvi

    2016-01-01

    There is a need for food-based solutions for preventing vitamin D deficiency. Vitamin D3 (D3) is mainly used in fortified food products, although the production of vitamin D2 (D2) is more cost-effective, and thus may hold opportunities. We investigated the bioavailability of D2 from UV......-irradiated yeast present in bread in an 8-week randomised-controlled trial in healthy 20–37-year-old women (n 33) in Helsinki (60°N) during winter (February–April) 2014. Four study groups were given different study products (placebo pill and regular bread=0 µg D2 or D3/d; D2 supplement and regular bread=25 µg D2/d......; D3 supplement and regular bread=25 µg D3/d; and placebo pill and D2-biofortified bread=25 µg D2/d). Serum 25-hydroxyvitamin D2 (S-25(OH)D2) and serum 25-hydroxyvitamin D3 (S-25(OH)D3) concentrations were measured at baseline, midpoint and end point. The mean baseline total serum 25-hydroxyvitamin D...

  4. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.

    Science.gov (United States)

    Sansone, Valeria A; Burge, James; McDermott, Michael P; Smith, Patty C; Herr, Barbara; Tawil, Rabi; Pandya, Shree; Kissel, John; Ciafaloni, Emma; Shieh, Perry; Ralph, Jeffrey W; Amato, Antony; Cannon, Steve C; Trivedi, Jaya; Barohn, Richard; Crum, Brian; Mitsumoto, Hiroshi; Pestronk, Alan; Meola, Giovanni; Conwit, Robin; Hanna, Michael G; Griggs, Robert C

    2016-04-12

    To determine the short-term and long-term effects of dichlorphenamide (DCP) on attack frequency and quality of life in hyperkalemic (HYP) and hypokalemic (HOP) periodic paralysis. Two multicenter randomized, double-blind, placebo-controlled trials lasted 9 weeks (Class I evidence), followed by a 1-year extension phase in which all participants received DCP. Forty-four HOP and 21 HYP participants participated. The primary outcome variable was the average number of attacks per week over the final 8 weeks of the double-blind phase. The median attack rate was lower in HOP participants on DCP than in participants on placebo (0.3 vs 2.4, p = 0.02). The 9-week mean change in the Physical Component Summary score of the Short Form-36 was also better in HOP participants receiving DCP (treatment effect = 7.29 points, 95% confidence interval 2.26 to 12.32, p = 0.006). The median attack rate was also lower in HYP participants on DCP (0.9 vs 4.8) than in participants on placebo, but the difference in median attack rate was not significant (p = 0.10). There were no significant effects of DCP on muscle strength or muscle mass in either trial. The most common adverse events in both trials were paresthesia (47% DCP vs 14% placebo, both trials combined) and confusion (19% DCP vs 7% placebo, both trials combined). DCP is effective in reducing the attack frequency, is safe, and improves quality of life in HOP periodic paralysis. These studies provide Class I evidence that DCP significantly reduces attack frequency in HOP but lacked the precision to support either efficacy or lack of efficacy of DCP in HYP. © 2016 American Academy of Neurology.

  5. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis

    Science.gov (United States)

    Burge, James; McDermott, Michael P.; Smith, Patty C.; Herr, Barbara; Tawil, Rabi; Pandya, Shree; Kissel, John; Ciafaloni, Emma; Shieh, Perry; Ralph, Jeffrey W.; Amato, Antony; Cannon, Steve C.; Trivedi, Jaya; Barohn, Richard; Crum, Brian; Mitsumoto, Hiroshi; Pestronk, Alan; Meola, Giovanni; Conwit, Robin; Hanna, Michael G.; Griggs, Robert C.

    2016-01-01

    Objective: To determine the short-term and long-term effects of dichlorphenamide (DCP) on attack frequency and quality of life in hyperkalemic (HYP) and hypokalemic (HOP) periodic paralysis. Methods: Two multicenter randomized, double-blind, placebo-controlled trials lasted 9 weeks (Class I evidence), followed by a 1-year extension phase in which all participants received DCP. Forty-four HOP and 21 HYP participants participated. The primary outcome variable was the average number of attacks per week over the final 8 weeks of the double-blind phase. Results: The median attack rate was lower in HOP participants on DCP than in participants on placebo (0.3 vs 2.4, p = 0.02). The 9-week mean change in the Physical Component Summary score of the Short Form–36 was also better in HOP participants receiving DCP (treatment effect = 7.29 points, 95% confidence interval 2.26 to 12.32, p = 0.006). The median attack rate was also lower in HYP participants on DCP (0.9 vs 4.8) than in participants on placebo, but the difference in median attack rate was not significant (p = 0.10). There were no significant effects of DCP on muscle strength or muscle mass in either trial. The most common adverse events in both trials were paresthesia (47% DCP vs 14% placebo, both trials combined) and confusion (19% DCP vs 7% placebo, both trials combined). Conclusions: DCP is effective in reducing the attack frequency, is safe, and improves quality of life in HOP periodic paralysis. Classification of evidence: These studies provide Class I evidence that DCP significantly reduces attack frequency in HOP but lacked the precision to support either efficacy or lack of efficacy of DCP in HYP. PMID:26865514

  6. 8周游泳运动对2型糖尿病大鼠周围神经病变的影响%Influence of 8-week swimming on peripheral neuropathy in type 2 diabetic rats

    Institute of Scientific and Technical Information of China (English)

    尚画雨; 夏志; 张丹; 黄玫梅; 上官若男; 苏全生

    2014-01-01

    AIM:To explore the influence of long-term swimming on peripheral neuropathy in type 2 diabetic rats.METHODS:Male Wistar rats were fed with a high-fat and high-fructose diet, and injected with streptozocin to estab-lish a model of type 2 diabetes mellitus.The rats were randomly divided into 4 groups:blank control group (C group), ex-ercise control group ( CE group ) , diabetes mellitus group ( DM group ) and diabetes mellitus +exercise group ( DME group).The rats in CE group and DME group received 8-week swimming training (6 d/week).The training time was 20, 30 and 45 min in the first 3 d,respectively, and then it increased to 60 min a day.Eight weeks later, the motor nerve conduc-tion velocity ( MNCV ) and the levels of tumor necrosis factor α( TNF-α) , interleukin 6 ( IL-6 ) and C-reactive protein ( CRP) in sciatic nerve tissues of the rats were measured .The morphological changes of the sciatic nerve were also observed under light microscope .RESULTS:Compared with DM group , 8-week swimming obviously accelerated the MNCV ( P0.05).The obvi-ous nerve injury in DM group was observed .However , the pathological change of the sciatic nerve in DME group was re-lieved.CONCLUSION:Eight-week swimming training significantly accelerates the MNCV , attenuates the nerve injury in diabetic rats and has protective effect on peripheral nerve , which may be correlated with relieving the inflammatory reaction .%目的:探讨长期游泳运动对2型糖尿病大鼠周围神经病变的影响及可能机制。方法:雄性Wistar大鼠高糖高脂饲料喂养联合链脲佐菌素注射制备成T2 DM大鼠模型后,随机分为空白对照组( C组)、单纯运动组( CE组)、糖尿病对照组( DM组)和糖尿病运动组( DME组)。 CE组和DME组进行8周游泳训练(6 d/week ),第1周前3 d练习时间分别为20、30和45 min,第4天起每天持续游泳60 min。运动8周后测定各组大鼠坐骨神经的传导速度(MNCV),以及该组

  7. A long hangover from party drugs: residual proteomic changes in the hippocampus of rats 8 weeks after γ-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination.

    Science.gov (United States)

    van Nieuwenhuijzen, Petra S; Kashem, Mohammed A; Matsumoto, Izuru; Hunt, Glenn E; McGregor, Iain S

    2010-07-01

    3,4-Methylenedioxymethamphetamine (MDMA) and gamma-hydroxybutyrate (GHB) are popular party drugs that are used for their euphoric and prosocial effects, and sometimes in combination. Both drugs increase markers of oxidative stress in the hippocampus and can cause lasting impairments in hippocampal-dependent forms of memory. To gain further information on the biochemical mechanisms underlying these effects, the current study examined residual changes in hippocampal protein expression measured 8 weeks after chronic administration of GHB (500mg/kg), MDMA (5mg/kg) or their combination (GHB/MDMA). The drugs were administered once a day for 10 days in an environment with an elevated ambient temperature of 28 degrees C. Results showed significant changes in protein expression, relative to controls, in all three groups: MDMA and GHB given alone caused residual changes in 8 and 5 proteins respectively, while the GHB/MDMA combination significantly changed 6 proteins. The altered proteins had roles in neuroplasticity, neuroprotection, intracellular signalling and cytoskeletal function. The largest change (-4.3-fold) was seen in the MDMA group with the protein C-crk: a protein implicated in learning-related neuroplasticity. The second largest change (3.0-fold) was seen in the GHB group in Glutathione-S-transferase (GST), a protein that protects against oxidative stress. Two cytoskeletal proteins (Tubulin Folding Cofactor B and Tropomyosin-alpha-3 chain) and one plasticity related protein (Neuronal Pentraxin-1 NP1) were similarly changed in both the MDMA and the GHB groups, while two intracellular signalling proteins (alpha-soluble NSF-attachment protein and subunits of the V-type proton ATPase) were changed in both the MDMA/GHB and the MDMA groups. These results provide some insight into the molecular pathways possibly underlying the lasting cognitive deficits arising from GHB and/or MDMA use.

  8. 8周跑台运动干预对雄性肥胖大鼠生殖功能的影响∗%Effect of 8 weeks treadmill exercise intervention on reproductive function in obese male rats

    Institute of Scientific and Technical Information of China (English)

    常波; 赵大林; 康媛; 姚婷婷; 刘冠琪; 韩俊超; 衣雪洁

    2016-01-01

    Purpose:The aim of this research was to explore the effects of 8 weeks exercise intervention on the reproductive func-tion of obese male rats, and to provide experimental evidence for the improvement of testicular dysfunction caused by obesity. Methods:The SD rats were used in this study. Create the obesity animal model with high fat diet, moderate load treadmill and imposed 8 weeks of aerobic exercise intervention. Then, body weight, weight of celiac fat tissue and testicular, sperm counts and activity, serum testosterone (T), serum luteinizing hormone (LH), follicle stimulating hormone (FSH) and Estradiol (E2) hormone were observed. Results:① Compared with the normal group, the body weight and fat body ratio of the obese group were significantly increased, the levels of serum testosterone, luteinizing hormone and follicle stimulating hormone were significantly decreased in the obese group, the estradiol was significantly increased; the testis index, sperm count and sperm motility Rate was significantly reduced . ② Compared with the obese group, the body weight and fat body ratio of obese ath-letes decreased significantly, the levels of serum testosterone, luteinizing hormone and follicle stimulating hormone were signif-icantly increased, estradiol decreased significantly;testis index, sperm count and sperm motility rate were evidently increased. Conclusion:①The long-term high-fat diet not only induces obesity, but also causes the sex hormone disturbances and a de-cline in sperm quality parameters. ②8 weeks of aerobic exercise intervention can effectively reduce the body weight and body fat ratio, improve the quality parameters of sperm, adjust sex hormone disorder and reduce the negative effects of obesity on re-productive function in male rats.%目的::本文旨在探讨8周运动干预对肥胖雄性大鼠生殖功能影响,为运动改善由于肥胖引起的睾丸功能障碍提供实验依据。方法:以SD大鼠为研究对象,通过高

  9. Effects of vitamin D2-fortified bread v. supplementation with vitamin D2 or D3 on serum 25-hydroxyvitamin D metabolites: an 8-week randomised-controlled trial in young adult Finnish women.

    Science.gov (United States)

    Itkonen, Suvi T; Skaffari, Essi; Saaristo, Pilvi; Saarnio, Elisa M; Erkkola, Maijaliisa; Jakobsen, Jette; Cashman, Kevin D; Lamberg-Allardt, Christel

    2016-04-14

    There is a need for food-based solutions for preventing vitamin D deficiency. Vitamin D3 (D3) is mainly used in fortified food products, although the production of vitamin D2 (D2) is more cost-effective, and thus may hold opportunities. We investigated the bioavailability of D2 from UV-irradiated yeast present in bread in an 8-week randomised-controlled trial in healthy 20-37-year-old women (n 33) in Helsinki (60°N) during winter (February-April) 2014. Four study groups were given different study products (placebo pill and regular bread=0 µg D2 or D3/d; D2 supplement and regular bread=25 µg D2/d; D3 supplement and regular bread=25 µg D3/d; and placebo pill and D2-biofortified bread=25 µg D2/d). Serum 25-hydroxyvitamin D2 (S-25(OH)D2) and serum 25-hydroxyvitamin D3 (S-25(OH)D3) concentrations were measured at baseline, midpoint and end point. The mean baseline total serum 25-hydroxyvitamin D (S-25(OH)D=S-25(OH)D2+S-25(OH)D3) concentration was 65·1 nmol/l. In repeated-measures ANCOVA (adjusted for baseline S-25(OH)D as total/D2/D3), D2-bread did not affect total S-25(OH)D (P=0·707) or S-25(OH)D3 (P=0·490), but increased S-25(OH)D2 compared with placebo (PD2 supplement was more effective than bread in increasing S-25(OH)D2 (PD2 and D3 supplementation increased total S-25(OH)D compared with placebo (P=0·030 and P=0·001, respectively), but D2 supplementation resulted in lower S-25(OH)D3 (PD2 from UV-irradiated yeast in bread was not bioavailable in humans. Our results support the evidence that D2 is less potent in increasing total S-25(OH)D concentrations than D3, also indicating a decrease in the percentage contribution of S-25(OH)D3 to the total vitamin D pool.

  10. CA19-9 decrease at 8 weeks as a predictor of overall survival in a randomized phase III trial (MPACT) of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone in patients with metastatic pancreatic cancer.

    Science.gov (United States)

    Chiorean, E G; Von Hoff, D D; Reni, M; Arena, F P; Infante, J R; Bathini, V G; Wood, T E; Mainwaring, P N; Muldoon, R T; Clingan, P R; Kunzmann, V; Ramanathan, R K; Tabernero, J; Goldstein, D; McGovern, D; Lu, B; Ko, A

    2016-04-01

    A phase I/II study and subsequent phase III study (MPACT) reported significant correlations between CA19-9 decreases and prolonged overall survival (OS) with nab-paclitaxel plus gemcitabine (nab-P + Gem) treatment for metastatic pancreatic cancer (MPC). CA19-9 changes at week 8 and potential associations with efficacy were investigated as part of an exploratory analysis in the MPACT trial. Untreated patients with MPC (N = 861) received nab-P + Gem or Gem alone. CA19-9 was evaluated at baseline and every 8 weeks. Patients with baseline and week-8 CA19-9 measurements were analyzed (nab-P + Gem: 252; Gem: 202). In an analysis pooling the treatments, patients with any CA19-9 decline (80%) versus those without (20%) had improved OS (median 11.1 versus 8.0 months; P = 0.005). In the nab-P + Gem arm, patients with (n = 206) versus without (n = 46) any CA19-9 decrease at week 8 had a confirmed overall response rate (ORR) of 40% versus 13%, and a median OS of 13.2 versus 8.3 months (P = 0.001), respectively. In the Gem-alone arm, patients with (n = 159) versus without (n = 43) CA19-9 decrease at week 8 had a confirmed ORR of 15% versus 5%, and a median OS of 9.4 versus 7.1 months (P = 0.404), respectively. In the nab-P + Gem and Gem-alone arms, by week 8, 16% (40/252) and 6% (13/202) of patients, respectively, had an unconfirmed radiologic response (median OS 13.7 and 14.7 months, respectively), and 79% and 84% of patients, respectively, had stable disease (SD) (median OS 11.1 and 9 months, respectively). Patients with SD and any CA19-9 decrease (158/199 and 133/170) had a median OS of 13.2 and 9.4 months, respectively. This analysis demonstrated that, in patients with MPC, any CA19-9 decrease at week 8 can be an early marker for chemotherapy efficacy, including in those patients with SD. CA19-9 decrease identified more patients with survival benefit than radiologic response by week 8. © The Author 2016. Published by Oxford University Press on behalf of the European

  11. 不同组合益生菌对0~8周龄犊牛生长性能及血清生化指标的影响%Effects of Different Combinations of Probiotics on Growth Performance and Serum Biochemical Parameters in Dairy Calves Aged from 0 to 8 Weeks

    Institute of Scientific and Technical Information of China (English)

    符运勤; 刁其玉; 屠焰; 王建红; 许先查

    2012-01-01

    This study examined the effects of different combinations of probiotics on growth performance and serum biochemical parameters in preruminant Chinese Holstein calves. Twenty-four newborn Holstein calves were randomly divided into 4 groups with 3 males and 3 females in each group. Calves were offered a basal diet including milk replacer, starter diet and Chinese wildrye (control diet, group A) , a basal diet supplemented with Bacillus licheniformis (group B) , a basal diet supplemented with Bacillus licheniformis and Bacillus subti-lis (group C) , and a basal diet supplemented with Bacillus licheniformis, Bacillus subtilis and Lactobacillus plantarum (group D) , respectively. The ratio of each microbial strain for group C and group D was 1:1 and 1:1:1 in the bacterial counts, respectively. Each calf was offered 2 ?1010 CFU of probiotics per day. The total trial period was 8 weeks, and divided into 0-2, 2-4, 4-6 and 6-8 weeks for each period. Body weight and body measurement were recorded and blood samples were collected fortnightly, feed intake and fecal score were recorded every day. The results showed that in the trial of 0-8 weeks, average daily gain of calves in the group B was significantly higher than that in the group A (P 0. 05 ). At the end of the trial, body structure index in groups B and D was higher than that in the group A (P 0. 05). It is concluded that adding Bacillus licheniformis into the diet for calves can increase average daily gain of calves in the trial of 0-8 weeks and body structure index at the end of the trial, and adding Bacillus licheniformis, Bacillus subtilis and Lactobacillus plantarum into the diet for calves can increase body structure index at the end of the trial. However, adding probiotics into the diet for calves has no effect on serum biochemical parameters of animals.%本试验旨在研究益生菌对犊牛生长性能和血清生化指标的影响.选取24头新生荷斯坦犊牛,随机分为4组,每组公母各1/2,分别饲

  12. A força muscular de mulheres idosas decresce principalmente após oito semanas de interrupção de um programa de exercícios com pesos livres The muscle strength of elderly women decreases specially 8 weeks after interruption of a muscle strengthening training program

    Directory of Open Access Journals (Sweden)

    Vagner Raso

    2001-12-01

    exercises for both upper and lower limbs. The 1-RM test was performed immediately after the training period and subsequently every four weeks (4th, 8th and 12th week. Values showed a statistically significant decrease on muscle strength of lower and upper limbs, specially after 8 weeks. In the 12th week, lower and upper limb muscle strength decreased 27.5% to 35.1%, respectively; however, decrease was more remarkable in the upper limb. A greater capacity of muscle strength maintenance after training interruption was observed in the lower limb (22.9% to 71.9% than in the upper limb (-14.8% to 16.1% when the absolute values of the detraining period were compared to the values at the beginning of the training period. These data allowed the authors to conclude that the weight training program interruption leads to a negative impact on muscle strength of elderly women, specially after 8 weeks.

  13. 2D Thinking of Public Participation & Social Management during the Transformation Period%转型期公众参与社会管理的二维思考

    Institute of Scientific and Technical Information of China (English)

    董慧萍

    2013-01-01

    Our country is in the special historical period of "social transformation ." Social transformation calls for the thinking change of social management .Public participation and social management are the ob-jective requirements of era development .This article suggests cultivating citizens'quality ,enhancing the level of public participation and social management ,creating external environment for public participation and social management ,and forming the favorable interaction between the public and government in social management so as to jointly facilitating the construction of the harmonious society .%我国目前正处于“社会转型”的特殊历史时期,社会转型迫切需要社会管理内涵的思维转变,公众参与社会管理是时代发展的客观要求。培养公民素质,提高公众参与社会管理的水平,营造公众参与社会管理的外部环境,形成公众与政府在社会管理中的良性互动,共同促进和谐社会建设。

  14. 围生期毒死蜱暴露致子代8周雄鼠睾丸组织的氧化损伤%Perinatal Exposure to Chlorpyrifos Induced Testicular Oxidative Damage in 8 Week Offspring Male Rat

    Institute of Scientific and Technical Information of China (English)

    徐肖倩; 张敏; 王学梅; 方鑫; 李海玲; 戴红; 肖瑞

    2015-01-01

    毒死蜱是目前全世界使用和销售量最大的有机磷杀虫剂之一。为探讨围生期毒死蜱暴露致8周雄性子鼠睾丸组织的氧化损伤,选择健康Wistar妊娠母鼠于妊娠期(gestation days, GD)第6天至子鼠出生后(postnatal days, PND)21天通过灌胃染毒0、0.75、1.35和2.70 mg•kg-1剂量的毒死蜱,待雄性子鼠8周龄取左侧睾丸实施组织病理学检查,右侧睾丸用以检测丙二醛(ma-leic dialdehyde, MDA)的含量和谷胱甘肽S转移酶(glutathione S transferases, GST)、谷胱甘肽过氧化物酶(glutathione peroxidase, GSH-Px)、总超氧化物歧化酶(total superoxide dismutase, T-SOD)的活力。结果表明,与对照组比较,随着染毒剂量的增加子鼠体重和睾丸、附睾脏器系数有下降的趋势(P>0.05);而MDA呈升高趋势(P>0.05)。各组T-SOD和1.35、2.70 mg•kg-1剂量组GSH-Px活力的下降及2.70 mg•kg-1剂量组GST活力的升高均有统计学意义(P0.05). The decrease in the activity of T-SOD of all dose groups, the increase of the activity of GSH-Px of 1.35 mg•kg-1 and 2.70 mg•kg-1 dose groups and the increase in activity of GST of 2.70 mg•kg-1 dose group were statistically significant (P<0.05). The histopathological examina-tion indicated that the testis of 2.70 mg•kg-1 dose group had significant damage. It is found that the semen volume was reduced and exfoliated spermatogenic cell was increased. Chlorpyrifos impaired the balance of antioxidant sys-tem, thus induced lipid peroxidation damage to the testis of 8 week rat by maternal exposure during GD 6—PND21 d. It is proposed that chlorpyrifos had potential and long-term toxic effect to male reproductive system by perinatal exposure.

  15. The effects of 8-week core training on the development of some motoric features among 18 year-old footballers18 yaş grubu futbolcularda 8 haftalik merkez bölge (core antrenmanlarının bazı motorik özelliklerin gelişimine etkisi

    Directory of Open Access Journals (Sweden)

    Yakup Akif Afyon

    2016-11-01

    Full Text Available The purpose of the present research is investigating the effects of core trainings on some motoric features (strength and speed among 18 year-old footballers. In the present research, 20 experiment group (age =18 years, body weight =71,66±6,61 kg, height =171,75±5,86 cm and 20 control group (age =18 years, body weight =70,66±5,74 kg, height =171,75±2,99 cm, the total of 40 certified footballers, who played in 2013-2014 season, participated in the present research. Before the trainings, pre-test scores (sit-up, push-up, plank, vertical jump, medicine ball throwing, 30 m speed were recorded. 30-35 minute core trainings, 2 days a week, for 8 weeks were conducted on the control group in addition to their regular training. Control group participants followed their regular yearly training program. At the end of the trainings, post-test scores of both groups were recorded by two experts in the field in accordance with the protocol. In order to evaluate the effects of 8-week core trainings of the strength development of footballers, paired t test was utilized for in-group comparisons and independent samples t test was utilized for inter-group comparisons. Consequently, it was observed that 8-week core training in addition to football trainings contributed to the strength and speed development among footballers. Accordingly, core trainings can be advised for football trainers, who work for youth teams of football clubs.   Özet Bu araştırmanın amacı 18 yaş grubu futbolcularda bölgesel (core antrenmanların bazı motorik özelliklerin (kuvvet ve sürat gelişimine etkisinin incelenmesidir. Araştırmaya 2013-2014 sezonunda lisanslı olarak futbol oynayan 20 denek grubundan (yaş =18 yıl, vücut ağırlığı =71,66±6,61 kg, boy =171,75±5,86 cm ve 20 kontrol grubundan (yaş =18 yıl, vücut ağırlığı =70,66±5,74 kg, boy =171,75±2,99 cm olmak üzere 40 futbolcu katıldı. Antrenmanlar öncesi grupların ön testleri (mekik,

  16. On introduction of participant flowcharts in research papers in medical periodicals%医学期刊研究性论文引入受试者流程图的探讨

    Institute of Scientific and Technical Information of China (English)

    李静然; 魏丽惠

    2011-01-01

    调查国外2010年出版的18种英文医学期刊,其中12种在原始研究类论文中采用受试者流程图;国内18种医学期刊,其中仅1种采用了流程图。医学期刊采用研究受试者流程图,可清楚概括研究的路径,使整个研究过程一目了然,并可体现论文作者的严谨态度,研究的科学性和可靠性,也便于期刊编辑识别研究是否真实,有否造假现象,可起到一定的监督作用。%Eighteen English medical periodicals published by foreign countries were investigated in this study and 12 of them found adopted flowcharts in original research papers. However, in 18 domestic medical periodicals, only one adopted flowcharts. Adopting participant flowcharts in medical periodicals can clearly summarize research path and make whole study process clear at a glance. At the same time, it can show the strict attitudes of the authors, the reasonability and authenticity of the researches. Meanwhile, it can help the editors to judge whether the research findings are true or not and has some supervisory functions.

  17. Ambivalent participation

    DEFF Research Database (Denmark)

    Groes-Green, Christian

    2012-01-01

    Participation in young peoples' sexual cultures in Maputo, Mozambique led to reflections about the field dynamics of power, participation, desire, and discomfort. Structural inequalities of race, gender, and educational status resulted in informants seeing me as a morally righteous person to whom...... they could not give open accounts about sexual practice. Attempting to overcome these barriers, I participated in excessive nightlife activities, and as a consequence they began viewing me as a more accepting and reliable person. Although breaking down these barriers provided invaluable insight......' continued participation. I show how negotiating the risks of participation may simultaneously satisfy the desire for knowledge and curb erotic desires....

  18. Unfolding Participation

    DEFF Research Database (Denmark)

    Saad-Sulonen, Joanna; Halskov, Kim; Eriksson, Eva

    2015-01-01

    The aim of the Unfolding Participation workshop is to outline an agenda for the next 10 years of participatory design (PD) and participatory human computer interaction (HCI) research. We will do that through a double strategy: 1) by critically interrogating the concept of participation (unfolding...... the concept itself), while at the same time, 2) reflecting on the way that participation unfolds across different participatory configurations. We invite researchers and practitioners from PD and HCI and fields in which information technology mediated participation is embedded (e.g. in political studies......, urban planning, participatory arts, business, science and technology studies) to bring a plurality of perspectives and expertise related to participation....

  19. Unfolding Participation

    DEFF Research Database (Denmark)

    Saad-Sulonen, Joanna; Halskov, Kim; Eriksson, Eva

    2015-01-01

    The aim of the Unfolding Participation workshop is to outline an agenda for the next 10 years of participatory design (PD) and participatory human computer interaction (HCI) research. We will do that through a double strategy: 1) by critically interrogating the concept of participation (unfolding......, urban planning, participatory arts, business, science and technology studies) to bring a plurality of perspectives and expertise related to participation.......The aim of the Unfolding Participation workshop is to outline an agenda for the next 10 years of participatory design (PD) and participatory human computer interaction (HCI) research. We will do that through a double strategy: 1) by critically interrogating the concept of participation (unfolding...... the concept itself), while at the same time, 2) reflecting on the way that participation unfolds across different participatory configurations. We invite researchers and practitioners from PD and HCI and fields in which information technology mediated participation is embedded (e.g. in political studies...

  20. Conceptualizing Participation

    DEFF Research Database (Denmark)

    Simovska, Venka; Bruun Jensen, Bjarne

    Although participation is not a new issue, it would be fair to say that consequential participation, which implies young people engaging in meaningful dialogue with adults and institutions and influencing decision-making processes in matters that concern them, is still in its infancy. This document...... and society. It then describes different forms, modes or qualities of participation and proposes a specific model of facilitating participatory work with young people - the IVAC approach (Investigation-Vision-Action-Change). The concept of action, types of actions aimed at initiating change and corresponding...... aims to set the scene for discussing young people's participation in different domains that have an impact on their lives. It outlines the meaning and different interpretations of the concept of "participation" before reviewing why participation is an important issue in relation to young people...

  1. Portable Myoelectric Brace Use Increases Upper Extremity Recovery and Participation But Does Not Impact Kinematics in Chronic, Poststroke Hemiparesis.

    Science.gov (United States)

    Willigenburg, Nienke W; McNally, Michael P; Hewett, Timothy E; Page, Stephen J

    2017-01-01

    The authors examined the efficacy of an 8-week regimen combining repetitive task-specific practice (RTP) with a myoelectric brace (RTP+Myomo) on paretic upper extremity (UE; use in valued activities, perceived recovery, and reaching kinematics) in 12 subjects (4 men; M age = 53.5 years; mean time poststroke = 61.7 months). Seven subjects were administered RTP+Myomo therapy, and 5 were administered RTP only. Both groups participated in individualized, 45-min therapy sessions occurring 3 days/week over an 8-week period. The arm, hand ability, activities of daily living, and perceptions of recovery subscales of the Stroke Impact Scale (SIS), as well as UE reaching kinematics, assessed before and after the intervention. Subjects in the RTP+Myomo group showed greater improvements on all SIS subscales, with the recovery scale reaching statistical significance (p = .03). Subjects in the RTP-only group showed a greater increase in hand velocity in the reach up task (p = .02), but no changes were observed in the range of shoulder flexion or elbow extension during reaching. None of the changes in kinematic outcome measures significantly correlated with any of the changes in SIS subscales. RTP integrating myoelectric bracing may be more beneficial than RTP only in improving self-reported function and perceptions of overall recovery. The authors observed no changes in the range of elbow extension, and no relationship between self-reported improvements and changes in reaching kinematics.

  2. Authoring Participation

    DEFF Research Database (Denmark)

    Papazu, Irina

    2016-01-01

    . By turning to material participation, a concept inspired by Noortje Marres and Jennifer Gabrys, the efforts put into Samsø’s energy transformation by the islanders are given specificity. While much literature on public participation foregrounds public meetings and other spaces for deliberation and debate...

  3. Effects of shortening the dry period of dairy cows on milk production, energy balance, health, and fertility: A systemtic review

    NARCIS (Netherlands)

    Knegsel, van A.T.M.; Drift, van der S.G.A.; Cermáková, J.; Kemp, B.

    2013-01-01

    A dry period of 6–8 weeks for dairy cows is generally thought to maximise milk production in the next lactation. However, the value of such a long dry period is increasingly questioned. In particular, shortening the dry period shifts milk production from the critical period after calving to the

  4. Effects of shortening the dry period of dairy cows on milk production, energy balance, health, and fertility: A systemtic review

    NARCIS (Netherlands)

    Knegsel, van A.T.M.; Drift, van der S.G.A.; Cermáková, J.; Kemp, B.

    2013-01-01

    A dry period of 6–8 weeks for dairy cows is generally thought to maximise milk production in the next lactation. However, the value of such a long dry period is increasingly questioned. In particular, shortening the dry period shifts milk production from the critical period after calving to the week

  5. Retrospective analysis of 55,769 HbA1c EQA results obtained from professional laboratories and medical offices participating in surveys organized by two European EQA centers over a nine-year period.

    Science.gov (United States)

    Morandi, Pierre-Alain; Deom, André; Kesseler, Dagmar; Cohen, Richard

    2011-01-01

    External Quality Assessment (EQA) is an essential tool for laboratories to monitor the performances of their analyses. It also allows a comparison of methods and types of laboratories (professional laboratories vs. medical offices). We, therefore, compared 55,769 HbA1c EQA results obtained between 1999 and 2008 by laboratories participating in EQA schemes organized by two European centers, Switzerland (center 1) and France (center 2). We used simple, nonparametrical statistics suited to EQA results to calculate the yearly and global precision performances. All the results, including the outliers, were included in the calculations. The best global precision performances were obtained by professional laboratories and medical offices using DCA POCT devices, followed by professional laboratories with the Integra, Hitachi, Cobas Mira, and HPLC groups of devices, and finally by both types of laboratories with the NycoCard POCT devices. When considering yearly precision performances, an overall improvement over time was observed for almost all diagnostic devices of center 1, whereas the trend was less clear for center 2. The HbA1c EQA results collected and analyzed over a 9-year period showed that the DCA POCT devices used either by professional laboratories or medical offices had better reproducibility than laboratory devices (other than POCT) and that a general improvement of yearly precision performances was observed, especially when frequent EQA schemes were organized. © 2011 Wiley-Liss, Inc.

  6. The examination of the effects of 8-week plyometric training on some physical fitness parameters of women handball players aged between 12-16 years old8 haftalık pliometrik antrenmanın 12-16 yaş kadın hentbolcuların bazı fiziksel uygunluk parametrelerine etkisinin incelenmesi

    Directory of Open Access Journals (Sweden)

    Ali Ağılönü

    2015-04-01

    Full Text Available The aim of this study was to examine the impacts of 8-week plyometric exercise on some physical fitness parameters of women handball players aged 12-16 years old. 40 women athletes, 20-subject and 20-control group, participated in the study. While both group participated in the exercises regularly, subject group joined extra plyometric exercises twice a week. Before exercises pretest and posttest were applied.For statistical analysis, Wilcoxon test was used for comparison of intra-group; Mann-Whitney U test was used for comparison of inter-group, and p<0.05 was accepted as significance level. Significance differences were accepted when the values of body weight, body fat percentage, right / left hand grip (grip strength, leg and back strength, balance, flexibility, vertical jump, standing long jump, reaction time and 30-meter sprint speed was lower than 0.05 P level (p<0.05.Consequently, it was found that a 8-week plyometric exercises had positive impacts on values of percentage of body fat, vertical jump, standing long jump, 30-meter sprint speed.As a result of this study, because specially designed plyometric exercises have positive impacts on some physical fitness parameters and increment in values of athletes’ individual performance is an important factor, it can be suggested that plyometric exercises should be applied on women handball players.ÖzetBu Araştırma, 8 haftalık pliometrik antrenmanın 12-16 yaş kadın hentbolcuların Göster göster Bazı FİZİKSEL Uygunluk parametrelerine etkisinin İncelenmesi Amacı Ile yapilmistir. 20 Deney oynayan Araştırmaya Aktif hentbol, 20 Ile kontrolün grubu olmak Üzere Toplam 40 kadın sporcu Gönüllü Olarak katılmışlardır. Deney A.Ş. Ile kontrolün grubu Düzenli Olarak hentbol antrenmanlarına devam ederken, deney grubuna hentbol antrenmanlarının 8 Hafta önemli yanında Haftada Iki gün pliometrik antrenman yaptırılmıştır. tıklayın Araştırma hazırlanan pliometrik

  7. In-season training periodization of professional soccer players

    Directory of Open Access Journals (Sweden)

    A Los Arcos

    2017-04-01

    Full Text Available The aim of this study was to quantify the seasonal perceived respiratory and muscular training loads (i.e., sRPEres-TL and sRPEmus-TL completed by elite-oriented young professional soccer players. Twentyfour players (20.3 ± 2.0 years belonging to the same reserve team of a Spanish La Liga club participated in this study. Only the players that were available to train for a whole week with the team and also to play the weekly game were considered: Starters, players that participated in the match for at least 45 min and Non- Starters, players that did not participate or played less than 45 minutes in the match. The competitive period was analysed after the division into 5x6-8 week blocks and 35x1 week microcycles. Data were also analysed with respect to number of days before the immediate match. Weekly TL variation across the in-season blocks was trivial-small for both groups except between Block 2 and Block 3 (ES= moderate. Substantial TL differences (ES= small–very likely were found between training days, the TL pattern being a progressive increase up to MD-3 followed by a decrease until MD-1. Except for the match, sRPEres-/sRPEmus-TL was very similar between Starters and Non-Starters. In summary, perceived TL across the season displayed limited variation. Coaches periodized training contents to attain the highest weekly TL 72 hours before the match to progressively unload the players between MD-3 and the match day. The data revealed that the TL arising from the weekly game was solely responsible for the observed higher weekly TL of Starters in comparison with Non-Starters.

  8. Claiming Participation

    DEFF Research Database (Denmark)

    Fabian, Louise; Samson, Kristine

    2015-01-01

    with participation are currently strong influential factors in Danish planning. The article explores the use of participatory DIY urban design in two cases: the relocation of beer drinkers in Enghave Square and the Carlsberg City development in Copenhagen, Denmark. Carlsberg City is the most thorough Danish example...

  9. Period Cramps

    Science.gov (United States)

    ... Too Tall or Too Short All About Puberty Period Cramps KidsHealth > For Kids > Period Cramps Print A ... re a girl who gets them. What Are Period Cramps? Lots of girls experience cramps before or ...

  10. The U.S. Antarctic Oversnow and Airborne Geophysical-Glaciological Research Program of the International Geophysical Year (IGY) 1957-58 Period from the View of a Research Scientist Participant

    Science.gov (United States)

    Behrendt, J. C.

    2005-12-01

    resupply of the seven U.S. stations in Antarctica). The Filchner Ice Traverse, on which I participated, encountered many crevasses. Vehicles broke through thin snow bridges and one man fell deep into a crevasse. Fortunately there were no deaths and only one serious injury resulting from crevasse accidents on the U.S. Program. Because of hidden agenda related to the Cold War, U.S. (and possibly Soviet) scientists felt that Antarctic research was a duty rather than a privilege as today. The U.S. air program averaged 3.8 deaths/year from 1955-1961 in contrast to 0.1 death/year since about 1970. At least three U.S. scientists died in the early period of the U.S. program. When, if ever, do the ends justify the means? It is one thing if mature individual researchers, professional technicians, aviators, and others take risks with full awareness of the hazards. But it is quite another thing if relatively naive graduate students and new Ph.D.s looking for adventure, such as my colleagues and I in the 1956-1962 period, are sent into harm's way without knowing specifically what they will face, by ambitious senior researchers pursuing their personal scientific objectives, even though these may be of vital national and international importance. I have worked both sides of this street in the past 50 years.

  11. Vascular adaptations to 8-week cycling training in older men.

    NARCIS (Netherlands)

    Thijssen, D.H.J.; Groot, P.C.; Smits, P.; Hopman, M.T.E.

    2007-01-01

    AIM: Because age-related changes in the large conduit arteries (increased wall thickness, and attenuated arterial compliance and endothelial function) are associated with cardiovascular pathology, prevention is of paramount importance. The effects of endurance training (i.e. walking or cycling) in o

  12. eParticipation Research

    DEFF Research Database (Denmark)

    Medaglia, Rony

    2011-01-01

    This paper provides an update of the existing eParticipation research state of the art, and a longitudinal analysis of the development of the eParticipation field based on a shared framework of analysis. Drawing on a literature search covering the period from April 2006 to March 2011 included, 123......, sometimes in counterintuitive directions. Drawing on the analysis, the conclusion section provides inputs for a research agenda. These include the need to move beyond a technological perspective, and encouraging the ongoing shift of research focus from government to citizens and other stakeholders....

  13. Efficacy and safety of fixed-dose combination therapy with olmesartan medoxomil and rosuvastatin in Korean patients with mild to moderate hypertension and dyslipidemia: an 8-week, multicenter, randomized, double-blind, factorial-design study (OLSTA-D RCT: OLmesartan rosuvaSTAtin from Daewoong).

    Science.gov (United States)

    Park, Jin-Sun; Shin, Joon-Han; Hong, Taek-Jong; Seo, Hong-Seog; Shim, Wan-Joo; Baek, Sang-Hong; Jeong, Jin-Ok; Ahn, Youngkeun; Kang, Woong-Chol; Kim, Young-Hak; Kim, Sang-Hyun; Hyon, Min-Su; Choi, Dong-Hoon; Nam, Chang-Wook; Park, Tae-Ho; Lee, Sang-Chol; Kim, Hyo-Soo

    2016-01-01

    The pill burden of patients with hypertension and dyslipidemia can result in poor medication compliance. This study aimed to evaluate the efficacy and safety of fixed-dose combination (FDC) therapy with olmesartan medoxomil (40 mg) and rosuvastatin (20 mg) in Korean patients with mild to moderate hypertension and dyslipidemia. This multicenter, randomized, double-blind, factorial-design study included patients aged ≥20 years with mild to moderate essential hypertension and dyslipidemia. Patients were randomly assigned to receive FDC therapy (40 mg olmesartan medoxomil, 20 mg rosuvastatin), 40 mg olmesartan medoxomil, 20 mg rosuvastatin, or a placebo. The percentage change from baseline in low-density lipoprotein cholesterol levels was compared between FDC therapy and olmesartan medoxomil, and the change from baseline in diastolic blood pressure was compared between FDC therapy and rosuvastatin 8 weeks after treatment. A total of 162 patients were included. The least square mean percentage change (standard error) from baseline in low-density lipoprotein cholesterol levels 8 weeks after treatment was significantly greater in the FDC than in the olmesartan medoxomil group (-52.3% [2.8%] vs -0.6% [3.5%], Polmesartan medoxomil and rosuvastatin is an effective, safe treatment for patients with hypertension and dyslipidemia. This combination may improve medication compliance in patients with a large pill burden.

  14. LiNi0.8Co0.2O2-based high-power lithium-ion battery positive electrodes analyzed by X-ray photoelectron spectroscopy: 4. Following calendar-life test for 8 weeks at 50 °C, 60% state-of-charge (3.747 V)

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, Daniel A; Haasch, Richard T.

    2017-01-01

    High-power lithium-ion batteries are rapidly replacing the nickel metal hydride batteries currently used for energy storage in hybrid electric vehicles. Widespread commercialization of these batteries for vehicular applications is, however, limited by calendar-life performance, thermal abuse characteristics, and cost. The Advanced Technology Development Program was established by the U.S. Department of Energy to address these limitations. An important objective of this program was the development and application of diagnostic tools that provide unique ways to investigate the phenomena that limit lithium-ion cell life, performance, and safety characteristics. This report introduces a set of six Surface Science Spectra xray photoelectron spectroscopy (XPS) comparison records of data collected from positive electrodes (cathode) harvested from cylindrically wound, 18650-type, 1 A h capacity cells. The cathodes included in this study are (1) fresh, (2) following three formation cycles, (3) following calendar-life test for 12 weeks at 40 C, 60% state-of-charge (SOC), (4) following calendar-life test for 8 weeks at 50 C, 60% SOC, (5) following calendar-life test for 8 weeks at 60 C, 60% SOC, and (6) following calendar-life test for 2 weeks at 70 C, 60% SOC.

  15. Treatment for periodic paralysis.

    Science.gov (United States)

    Sansone, V; Meola, G; Links, T P; Panzeri, M; Rose, M R

    2008-01-23

    Primary periodic paralyses are rare inherited muscle diseases characterised by episodes of flaccid weakness affecting one or more limbs, lasting several hours to several days, caused by mutations in skeletal muscle channel genes. The objective of this review was to systematically review treatment of periodic paralyses. We searched the Cochrane Neuromuscular Disease Group Trials Register, MEDLINE (from January 1966 to July 2007), and EMBASE (from January 1980 to July 2007) and any other available international medical library sources from the University of Milan for randomised trials. We included randomised (including cross-over studies) and quasi-randomised trials in participants with primary periodic paralyses, in which any form of treatment, including physical therapy and alternative therapies, was compared to placebo or another treatment. Our primary outcome measure was the change in attack severity or frequency by eight weeks from the start of treatment. Our secondary outcome measures were: change in muscle strength and mass; change in Quality of Life, using Short Form 36 (SF36) or similar; preference of treatment strategy; adverse effects at eight weeks. Three studies met our inclusion criteria. In one study dichlorphenamide (DCP) vs placebo was tested in two groups of participants: 42 with hypokalemic periodic paralysis (HypoPP) and 31 with hyperkalemic periodic paralysis (HyperPP), based on clinical criteria. Thirty-four of 42 participants with hypokalemic periodic paralysis completed both treatment phases. For the 34 participants having attack rate data for both treatment phases, the mean improvement in attack rate (P = 0.02) and severity-weighted attack rate (P = 0.01) on DCP relative to placebo were statistically significant. Fifteen preferred DCP, three placebo and six their baseline medication. Twenty-four of 31 participants with hyperkalemic periodic paralysis completed both treatment phases: for the 16 participants who had attack rate data for both

  16. Periodic paralysis.

    Science.gov (United States)

    Fontaine, Bertrand

    2008-01-01

    Periodic paralyses are rare diseases characterized by severe episodes of muscle weakness concomitant to variations in blood potassium levels. It is thus usual to differentiate hypokalemic, normokalemic, and hyperkalemic periodic paralysis. Except for thyrotoxic hypokalemic periodic paralysis and periodic paralyses secondary to permanent changes of blood potassium levels, all of these diseases are of genetic origin, transmitted with an autosomal-dominant mode of inheritance. Periodic paralyses are channelopathies, that is, diseases caused by mutations in genes encoding ion channels. The culprit genes encode for potassium, calcium, and sodium channels. Mutations of the potassium and calcium channel genes cause periodic paralysis of the same type (Andersen-Tawil syndrome or hypokalemic periodic paralysis). In contrast, distinct mutations in the muscle sodium channel gene are responsible for all different types of periodic paralyses (hyper-, normo-, and hypokalemic). The physiological consequences of the mutations have been studied by patch-clamp techniques and electromyography (EMG). Globally speaking, ion channel mutations modify the cycle of muscle membrane excitability which results in a loss of function (paralysis). Clinical physiological studies using EMG have shown a good correlation between symptoms and EMG parameters, enabling the description of patterns that greatly enhance molecular diagnosis accuracy. The understanding of the genetics and pathophysiology of periodic paralysis has contributed to refine and rationalize therapeutic intervention and will be without doubts the basis of further advances.

  17. eParticipation Research

    DEFF Research Database (Denmark)

    Medaglia, Rony

    2012-01-01

    Research on the use of information technology to support democratic decision-making (eParticipation) is experiencing ongoing growth, stimulated by an increasing attention from both practitioner and research communities. This study provides the first longitudinal analysis of the development of the e......Participation field based on a shared framework, capturing the directions that the research field of eParticipation is taking in recent developments. Drawing on a literature search covering the period from April 2006 to March 2011, this study identifies, analyzes, and classifies 122 research articles within...... also suggests new analytical categories of research. Drawing on the analysis, inputs for a research agenda are suggested. These include the need to move beyond a technological perspective, encouraging the ongoing shift of research focus from government to citizens and other stakeholders, and the need...

  18. 8周常规康复训练和本体感觉加强训练对半月板术后患者膝关节本体感觉和肌力影响的比较%Comparative Study on Effects of 8-week Conventional Rehabilitation and Proprioception Strengthen Training on Knee Joint Proprioception and Strength of Patients with Meniscectomy

    Institute of Scientific and Technical Information of China (English)

    李玉周; 胡英琪; 李国平

    2012-01-01

    目的:探讨8周常规康复训练和本体感觉加强训练对膝关节半月板术后患者膝关节本体感觉和肌力的影响,以指导临床康复训练.方法:25名半月板术后患者,依照均衡原则分为常规康复训练组(13人,以肌力和关节活动度训练为主)和本体感觉加强训练组(12人,以本体感觉训练为主).在8周训练的不同时间点,使用BIODEX PRO 3 SYS测定膝关节主动30°位置觉(术前和术后4、8周)及屈膝30°和60°股四头肌最大等长肌力(术前和术后8周),于术前和术后2、4、8周使用X-SENS测定三维位置觉.结果:8周不同康复训练后,两组患侧、健侧主动30°位置觉较术前均有加强,患侧变化有统计学意义(P=0.022),不同康复处方训练对患侧、健侧主动30°位置觉的影响无差异.8周不同处方训练后两组三维位置觉在4周和8周均有明显改善,不同处方训练对患侧、健侧三维位置觉的影响无差异.8周不同处方训练后两组患侧、健侧30°和60°等长肌力均呈增长趋势,不同处方训练对患侧、健侧30°和60°等长肌力的影响无显著性差异.结论:8周常规康复训练和本体感觉加强训练均能增强膝关节半月板术后患者主动30°位置觉和三维位置觉,但两种训练对本体感觉的影响无显著性差别,可能与其均增强了肌力有关.%Objective To compare the influences of 8 -week conventional rehabilitation and proprioception strengthen training on the knee joint proprioception and strength of patients with meniscectomy. Methods Twenty five patients with meniscectomy were randomly divided into two groups: conventional rehabilitation group (rc=13, mainly underwent muscle strength and motion of joint training) and proprioception strengthen training group (re =12,mainly underwent proprioception training). The active joint sense of position at 30° before,and 4 and 8 weeks after training,isometric strength of quadriceps femoris at 30° and 60

  19. Irregular Periods

    Science.gov (United States)

    ... blood become too low or too high. Some women have irregular periods because their bodies produce too much androgen, which is a hormone that causes increased muscle mass, facial hair, and deepening of the voice in males and ...

  20. Period Pain

    Science.gov (United States)

    ... You may also have other symptoms, such as lower back pain, nausea, diarrhea, and headaches. Period pain is not ... Taking a hot bath Doing relaxation techniques, including yoga and meditation You might also try taking over- ...

  1. Heart Rate Responses of High School Students Participating in Surfing Physical Education.

    Science.gov (United States)

    Bravo, Michelle M; Cummins, Kevin M; Nessler, Jeff A; Newcomer, Sean C

    2016-06-01

    Despite the nation's rising epidemic of childhood obesity and diabetes, schools struggle to promote physical activities that help reduce risks for cardiovascular disease. Emerging data suggest that adopting novel activities into physical education (PE) curriculum may serve as an effective strategy for increasing physical activity in children. The purpose of this investigation was to characterize activity in the water and heart rates (HRs) of high school students participating in surf PE courses. Twenty-four male (n = 20) and female (n = 4) high school students (mean age = 16.7 ± 1.0 years) who were enrolled in surf PE courses at 2 high schools participated in this investigation. Daily measurements of surfing durations, average HR, and maximum HR were made on the students with HR monitors (PolarFT1) over an 8-week period. In addition, HR and activity in the water was evaluated during a single session in a subset of students (n = 11) using a HR monitor (PolarRCX5) and a video camera (Canon HD). Activity and HR were synchronized and evaluated in 5-second intervals during data analyses. The average duration that PE students participated in surfing during class was 61.7 ± 1.0 minutes. Stationary, paddling, wave riding, and miscellaneous activities comprised 42.7 ± 9.5, 36.7 ± 7.9, 2.9 ± 1.4, and 17.8 ± 11.4 percent of the surf session, respectively. The average and maximum HRs during these activities were 131.1 ± 0.9 and 177.2 ± 1.0 b·min, respectively. These data suggest that high school students participating in surf PE attained HRs and durations that are consistent with recommendations with cardiovascular fitness and health. In the future, PE programs should consider incorporating other action sports into their curriculum to enhance cardiovascular health.

  2. 重性抑郁发作缓解后8周和2年的疗效及其预测因素%The outcomes and outcome predictive factors of major depressive episodes at 8 weeks and 2 years after discharge

    Institute of Scientific and Technical Information of China (English)

    韩自力; 甘照宇; 唐秀梅; 张晋碚

    2011-01-01

    Objective To reevaluate major depressive episodes' treatment outcome at 8 weeks and 2 years after transitory remission ( remission time lasted 1 - 7 weeks ) based on the redefinition of treatment outcomes for major depressive episodes( MDE ) and to explore the predictive factors for outcomes. Methods A 2-year open, prospective and natural study was conducted on 84 inpatients with MDE who had achieved transitory remission at discharge and their outcomes were assessed using 24-item Hamilton depression rating scale ( HAMD ), Bech-Rafaelsen mania scale( BRMS ) and self-made questionnaire. Results At 8 weeks after discharge, 46.4% ( 39/84 ) patients remained in remission ( remission time lasted 8 weeks or longer ) , 10.7% ( 9/84 ) patients experienced subthreshold episode, 21.4% ( 18/84 ) patients presented residual symptoms and 21.4% ( 18/84 ) patients relapsed. At 2 years after discharge, 39.3% ( 33/84 )patients completely recovered, 25.0%( 21/84 )patients partially recovered, 35.7% ( 30/84 )patients had a chronic course or frequently recurred.Binary logistic regression analysis showed that remission at 8 weeks after discharge was associated with illness duration( P =0.047, OR =0.89,β =-0.12 ), and recovery at 2 years after discharge was associated with the remission at 8 weeks after discharge ( P < 0.001,OR = 109.97 ,β = 4.70 ) and treatment compliance (P=0.002, OR =0.23 , β=-1.46 ). Age,sex, comorbidity, psychotic features, numher of episodes, illness severity, family history, unipolar or bipolar disorder didn't significantly affect the short-term and long-term treatment outcomes ( P > 0.05 ). Conclusions Remission should bethe treatment goal for patients with acute MDE and good long-term outcomes for patients with MDE depend on an early,complete and whole-course treatment.%目的 基于对重性抑郁发作疗效的重新定义,重新评价重性抑郁发作暂时缓解后8周和2年后的疗效并探讨其预测因素.方法

  3. Periodic behaviors

    CERN Document Server

    Napp, Diego; Shankar, Shiva

    2010-01-01

    This paper studies behaviors that are defined on a torus, or equivalently, behaviors defined in spaces of periodic functions, and establishes their basic properties analogous to classical results of Malgrange, Palamodov, Oberst et al. for behaviors on R^n. These properties - in particular the Nullstellensatz describing the Willems closure - are closely related to integral and rational points on affine algebraic varieties.

  4. PERIODIC BEHAVIORS

    NARCIS (Netherlands)

    Napp, Diego; Put, Marius van der; Shankar, Shiva

    2010-01-01

    This paper studies behaviors that are defined on a torus, or equivalently, behaviors defined in spaces of periodic functions, and establishes their basic properties analogous to classical results of Malgrange, Palamodov, Oberst et al. for behaviors on R(n). These properties-in particular the Nullste

  5. Effects of Wujiabugu Recipe on Changes of Bone in Rats after 3 Weeks Tail-suspension and 8 Weeks Detail-suspension Recovery%五加补骨方对尾吊3周及解悬吊8周大鼠骨变化的影响

    Institute of Scientific and Technical Information of China (English)

    朱斌; 郝喜娟; 傅骞; 杨佳佳; 李英贤; 胡素敏

    2011-01-01

    目的 观察大鼠尾吊模拟失重3周及解悬吊恢复8周后骨密度(BMD)及骨力学(biomechanics)的变化情况,探讨五加补骨方对其干预效果.方法 雄性Wistar大鼠,按体重随机分为4组:对照组(Con)、模型组(Mod)、五加全程给药组(A),五加恢复期给药组(B).A组全程给予五加补骨方水煎液灌胃,B组在8周恢复期给予与A组等剂量的五加补骨方水煎液灌胃.3周尾吊结束时及解悬吊8周时,取材测量不同部位BMD及骨力学性能.结果 与对照组相比,尾吊3周后模型组、A组和B组的股骨、胫骨、第四腰椎BMD显著下降(P0.05);模型组,A组和B组股骨和肱骨最大载荷和弹性载荷同对照组比无显著变化.结论 尾吊3周模拟失重可以造成大鼠承重骨BMD和骨力学显著降低,而五加补骨方具有明显对抗骨丢失的作用;在恢复期,骨密度及骨力学恢复缓慢,五加补骨方在一定程度上可以促进大鼠骨丢失的恢复.全程给予五加补骨方对抗骨丢失的疗效明显好于解悬吊后再给药.%Objective To observe the effects of a Chinese recipe - wujiabugu, on bone mineral density (BMD) and biomechanics of rats after 3 weeks tail suspension (TS) and 8 weeks de-tail-suspension recovery. Methods Fifty- six male Wistar rats were randomly divided into group control (Con), group model ( Mod) , group Awujiabugu recipe and group Bwujiabugu recipe. During the experiment (11 weeks) , group A was given wujiabugu decoction. Group B were given demineralized water during TS, then wujiabugu decoction in reambulation. Following TS and 8 weeks recovery, their BMD and biomechanics were examined respectively. Results At the end of TS, compared with Con, the BMD of femur, tibia and the 4th lumbar vertebra of the other 3 groups significantly decreased ( P < 0.001) ; The femur maximum load and elastic load decreased (P < 0. 01) too. BMD in Group A was much higher than those in group Mod and B. After 8 weeks recovery, there was

  6. Efficacy and safety of fixed-dose combination therapy with olmesartan medoxomil and rosuvastatin in Korean patients with mild to moderate hypertension and dyslipidemia: an 8-week, multicenter, randomized, double-blind, factorial-design study (OLSTA-D RCT: OLmesartan rosuvaSTAtin from Daewoong

    Directory of Open Access Journals (Sweden)

    Park JS

    2016-08-01

    -blind, factorial-design study included patients aged ≥20 years with mild to moderate essential hypertension and dyslipidemia. Patients were randomly assigned to receive FDC therapy (40 mg olmesartan medoxomil, 20 mg rosuvastatin, 40 mg olmesartan medoxomil, 20 mg rosuvastatin, or a placebo. The percentage change from baseline in low-density lipoprotein cholesterol levels was compared between FDC therapy and olmesartan medoxomil, and the change from baseline in diastolic blood pressure was compared between FDC therapy and rosuvastatin 8 weeks after treatment. A total of 162 patients were included. The least square mean percentage change (standard error from baseline in low-density lipoprotein cholesterol levels 8 weeks after treatment was significantly greater in the FDC than in the olmesartan medoxomil group (–52.3% [2.8%] vs –0.6% [3.5%], P<0.0001, and the difference was –51.7% (4.1% (95% confidence interval: –59.8% to –43.6%. The least square mean change (standard error from baseline in diastolic blood pressure 8 weeks after treatment was significantly greater in the FDC group than in the rosuvastatin group (–10.4 [1.2] mmHg vs 0.1 [1.6] mmHg, P<0.0001, and the difference was –10.5 (1.8 mmHg (95% confidence interval: –14.1 to –6.9 mmHg. There were 50 adverse events in 41 patients (22.7% and eight adverse drug reactions in five patients (2.8%. The study found that FDC therapy with olmesartan medoxomil and rosuvastatin is an effective, safe treatment for patients with hypertension and dyslipidemia. This combination may improve medication compliance in patients with a large pill burden. Keywords: fixed-dose combination therapy, olmesartan medoxomil, rosuvastatin, hypertension, dyslipidemia

  7. Marketing to increase participation in a Web-based continuing medical education cultural competence curriculum.

    Science.gov (United States)

    Estrada, Carlos A; Krishnamoorthy, Periyakaruppan; Smith, Ann; Staton, Lisa; Korf, Michele J; Allison, Jeroan J; Houston, Thomas K

    2011-01-01

    CME providers may be interested in identifying effective marketing strategies to direct users to specific content. Online advertisements for recruiting participants into activities such as clinical trials, public health programs, and continuing medical education (CME) have been effective in some but not all studies. The purpose of this study was to compare the impact of 2 marketing strategies in the context of an online CME cultural competence curriculum (www.c-comp.org). In an interrupted time-series quasi-experimental design, 2 marketing strategies were tested: (1) wide dissemination to relevant organizations over a period of approximately 4 months, and (2) Internet paid search using Google Ads (5 consecutive 8-week periods--control 1, cultural/CME advertisement, control 2, hypertension/ content advertisement, control 3). Outcome measures were CME credit requests, Web traffic (visits per day, page views, pages viewed per visit), and cost. Overall, the site was visited 19,156 times and 78,160 pages were viewed. During the wide dissemination phase, the proportion of visits requesting CME credit decreased between the first (5.3%) and second (3.3%) halves of this phase (p = .04). During the Internet paid search phase, the proportion of visits requesting CME credit was highest during the cultural/CME advertisement period (control 1, 1.4%; cultural/CME ad, 4.3%; control 2, 1.5%; hypertension/content ad, 0.6%; control 3, 0.8%; p Education, the Society for Academic Continuing Medical Education, and the Council on CME, Association for Hospital Medical Education.

  8. Účinek osmitýdenního plicního rehabilitačního programu na hrudní mobilitu a maximální vdechový a výdechový ústní tlak u pacientů s bronchiálním astmatem The effect of 8 week pulmonary rehabilitation programme on chest mobility and maximal inspiratory and expiratory mouth pressure in patients with bronchial asthma

    Directory of Open Access Journals (Sweden)

    Ivan Vařeka

    2008-04-01

    íjení hrudníku v obou úrovních a zvýšení hodnot maximálních nádechových a výdechových ústních tlaků. Zvýšení rozvíjení hrudníku a hodnot maximálních nádechových a výdechových ústních tlaků je velmi důležité pro nemocné s bronchiálním astmatem, neboť může vést ke snazšímu dýchání, menšímu nádechovému úsilí a menší únavě. Z tohoto důvodu by měla být respirační fyzioterapie součástí komprehensivní péče o nemocné s bronchiálním astmatem. Bronchial asthma (AB can lead not only to breathing disorders but also to musculoskeletal disorders. Breathing and musculoskeletal disorders can lead to health problems and decreased quality of life. These disorders may be also associated with psychosocial problems and could influence adult participation in various activities (physical activities and sports, activities of daily living – shopping, cleaning house, etc.. Breathlessness and cough are usually the most problematic symptoms of AB. Comprehensive care is based on medical treatment and non pharmacological treatment. Chest physiotherapy is an important part of the non pharmacological treatment, but the optimal medical treatment is also necessary for successful rehabilitation. The aim of this study was to find out if the pulmonary rehabilitation programme can influence the maximal inspiratory and expiratory mouth pressure and chest mobility of AB patients. The examined group consisted of 23 patients with AB. All AB patients had intermittent mild asthma and they were medically stable patients. All of them underwent an 8 week pulmonary rehabilitation programme (visits were twice a week, 30 minutes in length. The 8 week pulmonary rehabilitation programme was focused on breathing exercises (diaphragmatic breathing, activation of expiration, eff ective cough training, etc. and on soft tissue techniques for releasing thoracic and shoulder muscles and fascias. Maximal inspiratory and expiratory mouth pressure and chest mobility

  9. 12 CFR 370.5 - Participation.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Participation. 370.5 Section 370.5 Banks and... LIQUIDITY GUARANTEE PROGRAM § 370.5 Participation. (a) Initial period. All eligible entities are covered under the temporary liquidity guarantee program for the period from October 14, 2008, through December...

  10. 10 CFR 603.1295 - Periodic audit.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Periodic audit. 603.1295 Section 603.1295 Energy... Used in this Part § 603.1295 Periodic audit. An audit of a participant, performed at an agreed-upon... an audit may cover. A periodic audit of a participant differs from an award-specific audit of...

  11. La participation des femmes dans le conflit interne armé au Pérou durant la période 1980-2000 The Participation of Women in Peru’s Internal Armed Conflict during the 1980-2000 Period La participación de las mujeres en el conflicto armado peruano durante 1980-2000

    Directory of Open Access Journals (Sweden)

    Rocío Silva Santisteban

    2012-05-01

    Full Text Available Entre 1980 et 2000, le Pérou a vécu un conflit interne armé qui s’est soldé par un nombre de victimes sans précédent dans l’histoire de l’Amérique latine. Les protagonistes de la lutte armée furent aussi bien des collectifs subversifs (PCP-SL et MRTA que l’Armée et la Police ainsi que la population paysanne organisée en milices (rondes paysannes. Les conséquences furent évidemment dramatiques puisqu’en plus des nombreuses pertes humaines qu’il faut déplorer se combinait la tragique désagrégation du lien social. Les femmes qui participèrent directement ou indirectement au conflit, si elles ne sont pas aujourd’hui décédées, portent les stigmates des affrontements : cicatrices, viols, grossesses non désirées, stress post-traumatique. Il s’agit ici des victimes des deux camps, mais aussi de celles qui se sont converties en agent de la justice pour récupérer leurs proches, leurs époux et leurs fils, formant ainsi les premiers collectifs de revendication des droits de l’homme. Cependant, celles qui ont bénéficié de la reconnaissance médiatique sont sans nul doute celles qui ont perpétré les crimes : les femmes qui ont pris les armes comme militantes, combattantes ou comme membres des forces de l’ordre.Between 1980 and 2000, Peru experienced an internal armed conflict that resulted in victims in numbers unprecedented in the history of Latin America. The protagonists of the armed struggle included the subversive collectives (PCP-SL and MRTA, as much as the army, the police and the rural militias («ronde paysanne».  The consequences were dramatic in that the sheer human losses were compounded by a tragic unraveling of the social fabric. Women who participated directly or indirectly in the conflict – if they still live – bear the stigmata of their experience:  scars, rape, post-traumatic stress. Here, we consider the victims of both camps, but also those women who became justice agents making

  12. THE EFFECT OF TAPERING PERIOD ON PLASMA PRO-INFLAMMATORY CYTOKINE LEVELS AND PERFORMANCE IN ELITE MALE CYCLISTS

    Directory of Open Access Journals (Sweden)

    Peter M. Tiidus

    2009-12-01

    Full Text Available The aim of this study was to investigate the effect of two different tapering period lengths on the concentration of plasma interleukin- 6 (IL-6, interleukin (IL-1β and tumor necrosis factor-? (TNF-α and performance in elite male cyclists. To this end, after completing 8 weeks progressive endurance exercise, twenty four high-level endurance cyclists were randomly assigned to one of two groups: a control group of cyclists (n = 12 continued performing progressive weekly training volume for 3 weeks while a taper group of cyclists (n = 12 proceeded with a 50% reduction in weekly training volume relative to the control group. A simulated 40 min time trial (40TT performance ride was used as the criterion index of performance before and after the tapering period to evaluate the physiological and performance effects of each protocol. Blood samples were collected immediately post-40TT from all participants at the beginning of week 1, and the end of weeks 4, 8, 9 and 11. IL-1β, IL-6 and TNFα were assayed using a standard commercial ELISA kits (Quantikine; R & D Systems, Minneapolis, MN. The mean time to complete the 40TT in the taper group decreased significantly (p < 0.01 after both 1 and 3 weeks with reduced training volume relative to the control group. There were significant reductions in (p < 0.001 IL-1β, IL-6 and TNFα concentrations in the taper group relative to the control group at the end of the 3 week tapering period, but not at the end of the 1 week tapering period. These results demonstrate that both a 1 and a 3 week taper period will result in improved physical performance in trained cyclists but only a 3 week taper period will result in attenuation of post-exercise pro- inflammatory cytokines when compared to those continuing a more intense training regimen

  13. 家属参与围手术期心理干预对未成年人人工流产的影响%Influences of family’s participation in psychological interven-tion in peroperative period on induced abortion of minors

    Institute of Scientific and Technical Information of China (English)

    张新艳

    2013-01-01

    Objective To explore the influences of family’s participation in psychological intervention in peroperative period on induced abortion of minors .Methods A total of 150 minors receiving induced abor-tion and their families participating in psychological intervention in peroperative period were assigned to observation group and 150 ones their families without participation to control group ;preoperative anxiety , intraoperative pain ,incidence of induced abortion syndrome ,post-operative vaginal hemorrhage and men-struation recovery time were observed and statistically analyzed for both groups .Results The detection rate of anxious emtion and incidence of induced abortion syndrome were significantly lower (P< 0 .01) , pain degrees slighter (P< 0 .01) and vaginal hemorrhage and menstruation recovery time shorter (P<0 .01) in observation than control group .Conclusion Family’s participation in psychological intervention in peroperative period could effectively relieve minors ’ anxious emotion ,improve their tolerance to the op-eration ,lessen pain degree ,reduce the development of induced abortion syndrome and is beneficial to post-operation somatic recovery .%目的探讨家属参与围术期心理干预对未成年人人工流产的影响。方法将150例家属参与围手术期心理干预的未成年人人工流产患者设为观察组,150例无家属参与者设为对照组,观察两组患者术前焦虑情况、术中疼痛程度、人流综合征的发生率及术后阴道出血和月经恢复时间,并进行统计分析。结果观察组焦虑情绪检出率、人流综合征发生率显著低于对照组(P<0.01),疼痛程度显著轻于对照组(P<0.01),阴道出血时间及月经恢复时间均显著少于对照组(P<0.01)。结论家属参与人工流产围手术期心理干预,能有效缓解未成年人的焦虑情绪,提高其手术耐受力减轻疼痛程度,减少人流综合征的发生,有利于术后身体的恢复。

  14. Effect of hippotherapy on perceived self-competence and participation in a child with cerebral palsy.

    Science.gov (United States)

    Frank, Alana; McCloskey, Sandra; Dole, Robin L

    2011-01-01

    This case report highlights changes in self-competence and social acceptance, along with changes in functional skills, after an 8-week program of hippotherapy. A 6-year-old girl with mild ataxic cerebral palsy, level I Gross Motor Functional Classification System, exhibited typical impairments in body systems and functions that affected her participation in age-appropriate functional and leisure activities. The child's performance on the Gross Motor Function Measure-66, the Pediatric Outcomes Data Collection Instrument, and the Pictorial Scale of Perceived Competence and Social Acceptance for Young Children were examined at baseline, after the 8-week intervention, and at a 2-month follow-up session. Data at 8 weeks demonstrated positive changes in all areas, with improvements continuing for 2 months after the program's completion. Hippotherapy not only may be an effective intervention to improve functional gross motor development but also may affect perceived self-competence and social acceptance, which may lead to increases in participation for children with mild cerebral palsy.

  15. Monaural occlusion alters sound localization during a sensitive period in the barn owl.

    Science.gov (United States)

    Knudsen, E I; Esterly, S D; Knudsen, P F

    1984-04-01

    Sound localization was disrupted in young barn owls by chronically plugging one ear. Owls that were younger than 8 weeks of age at the time of ear plugging recovered normal localization accuracy while plugged, whereas those that were older than 8 weeks at the time of ear plugging did not. The end of the sensitive period for the adjustment of sound localization accuracy coincides with the maturation of the head and ears, suggesting that the exposure of the auditory system to stable, adult-like acoustic cues could play a role in bringing the sensitive period to a close. The results demonstrate that, early in development, associations between auditory cues and locations in space can be altered by experience.

  16. High-intensity preoperative training improves physical and functional recovery in the early post-operative periods after total knee arthroplasty

    DEFF Research Database (Denmark)

    Calatayud, Joaquin; Casaña, Jose; Ezzatvar, Yasmin;

    2017-01-01

    -four subjects (7 men, 37 women) scheduled for unilateral TKA for osteoarthritis (OA) during 2014 participated in this randomized controlled trial. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Physical Functioning Scale of the Short Form-36 questionnaire (SF-36), a 10-cm visual...... analogue scale (VAS), isometric knee flexion, isometric knee extension, isometric hip abduction, active knee range of motion and functional tasks (Timed Up and Go test and Stair ascent-descent test) were assessed at 8 weeks before surgery (T1), after 8 weeks of training (T2), 1 month after TKA (T3...

  17. Sports participation with arachnoid cysts.

    Science.gov (United States)

    Strahle, Jennifer; Selzer, Béla J; Geh, Ndi; Srinivasan, Dushyanth; Strahle, MaryKathryn; Martinez-Sosa, Meleine; Muraszko, Karin M; Garton, Hugh J L; Maher, Cormac O

    2016-04-01

    OBJECT There is currently no consensus on the safety of sports participation for patients with an intracranial arachnoid cyst (AC). The authors' goal was to define the risk of sports participation for children with this imaging finding. METHODS A survey was prospectively administered to 185 patients with ACs during a 46-month period at a single institution. Cyst size and location, treatment, sports participation, and any injuries were recorded. Eighty patients completed at least 1 subsequent survey following their initial entry into the registry, and these patients were included in a prospective registry with a mean prospective follow-up interval of 15.9 ± 8.8 months. RESULTS A total 112 patients with ACs participated in 261 sports for a cumulative duration of 4410 months or 1470 seasons. Of these, 94 patients participated in 190 contact sports for a cumulative duration of 2818 months or 939 seasons. There were no serious or catastrophic neurological injuries. Two patients presented with symptomatic subdural hygromas following minor sports injuries. In the prospective cohort, there were no neurological injuries CONCLUSIONS Permanent or catastrophic neurological injuries are very unusual in AC patients who participate in athletic activities. In most cases, sports participation by these patients is safe.

  18. 抑郁症共病糖尿病患者的皮质醇水平与帕罗西汀治疗的疗效%Higher level of serum cortisol associated with less responses of 8 week paroxetine treatment in patients with depression comorbid type 2 diabetes

    Institute of Scientific and Technical Information of China (English)

    任会鹏; 王育梅; 宋美; 王学义

    2012-01-01

    group according to the serum concentration of cortisol. They were assessed with the Hamilton Depression Scale (HAMD) for severity of depression symptom and assessed with a self-made questionnaire for demographic data, living habits, and course of disease. Their body mass indices were calculated and the levels of glycosylated hemoglobin were measured. The two groups both received 8-week treatment of paroxetine, and the treatment effect was evaluated with the HAMD score-reducing rate. Results: Logistic regression analysis showed that higher level of glycosylated hemoglobin (HbAlc ≥6. 5% , OR = 2. 72; HbAlc ≥8. 0% , Off = 5.69), HAMD score of ≥20 (Off =3.31), body mass index of 3:25 ( OR = 3. 56), and age of 35 - 50 (OR - 2. 37) were risk factors of higher cortisol level. The exercise time of ≥ 4 h per week (Off =0. 28) and depression course of > 12 months (OR =0. 10) were protective factors. After 8-week treatment with paroxetine, the HAMD score-reducing rates were higher in high cortisol group than in normal cortisol group [ (0. 66 ± 0. 11) vs. (0. 86 ± 0. 05), P < 0. 01 ]. The HAMD score-reducing rates were negatively correlated with the levels of glycosylated hemoglobin (β = - 0. 26, P < 0. 05) and cortisol (β = - 0. 17, P <0. 05). Conclusion: It suggests that higher level of glycosylated hemoglobin, more severe symptom of depression, higher body mass index, age of 35 - 50 years may be the risk factors of increasing cortisol; longer exercise time and longer course of depression may be the protective factors. The patients with higher levels of cortisol and glycosylated hemoglobin may have poorer response to paroxetine treatment.

  19. Efficacy and safety of two fixed-dose combinations of S-amlodipine and telmisartan (CKD-828 versus S-amlodipine monotherapy in patients with hypertension inadequately controlled using S-amlodipine monotherapy: an 8-week, multicenter, randomized, double-blind, Phase III clinical study

    Directory of Open Access Journals (Sweden)

    Ihm SH

    2016-11-01

    Full Text Available Sang-Hyun Ihm,1 Hui-Kyung Jeon,1 Tae-Joon Cha,2 Taek-Jong Hong,3 Sang-Hyun Kim,4 Nae-Hee Lee,5 Jung Han Yoon,6 Namsik Yoon,7 Kyung-Kuk Hwang,8 Sang-Ho Jo,9 Ho-Joong Youn1 1Division of Cardiology, Department of Internal Medicine, The Catholic University of Korea, Seoul, 2Division of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, 3Division of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Busan, 4Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, 5Department of Cardiology, Soonchunhyang University Hospital, Bucheon, 6Division of Cardiology, Wonju College of Medicine, Yonsei University, Wonju, 7Department of Cardiology, Chonnam National University Hospital, Gwangju, 8Department of Internal Medicine, Chungbuk National University, College of Medicine, Cheongju, 9Division of Cardiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, South Korea Purpose: To evaluate the blood pressure (BP lowering efficacy and safety of CKD-828, a fixed-dose combination of S-amlodipine (the more active isomer of amlodipine besylate, which is calcium channel blocker and telmisartan (long acting angiotensin receptor blocker, in patients with hypertension inadequately controlled with S-amlodipine monotherapy.Patients and methods: Eligible patients (N=187 who failed to respond after 4-week S-amlodipine 2.5 mg monotherapy (sitting diastolic blood pressure [sitDBP] ≥90 mmHg to receive CKD-828 2.5/40 mg (n=63, CKD-828 2.5/80 mg (n=63, or S-amlodipine 2.5 mg (n=61 for 8 weeks. The primary efficacy endpoint, mean sitDBP change from baseline to Week 8, was compared between the combination (CKD-828 2.5/40 mg and CKD-828 2.5/80 mg and S-amlodipine monotherapy groups. The safety was assessed based on adverse events, vital signs, and physical examination findings.Results: After the 8

  20. 饲粮粗蛋白质和代谢能水平对4~8周龄四川白鹅生产性能和氮平衡的影响%Effects of Dietary Crude Protein and Metabolizable Energy Levels on Performance and Nitrogen Balance of Sichuan White Geese Aged from 4 to 8 Weeks

    Institute of Scientific and Technical Information of China (English)

    李琴; 陈明君; 彭祥伟

    2015-01-01

    本试验旨在研究饲粮粗蛋白质( CP)和代谢能( ME)水平对4~8周龄四川白鹅生产性能和氮平衡的影响。采用3×3双因素试验设计,设3个ME水平(12.86、12.13、11.43 MJ/kg)和3个CP水平(17%、15%、13%),配制9种试验饲粮。选择540只体重相近、健康的22日龄四川白鹅,随机分成9组,每组4个重复,每个重复15只。试验期为35 d。在试验第21天,每组挑选8只体重接近各组平均体重的试验鹅进行代谢试验。结果表明:1) CP水平对料重比有显著影响(P<0.05),ME水平对日干物质(DM)采食量、料重比有极显著影响(P<0.01),CP和ME水平的互作对日DM采食量有极显著影响( P<0.01)。随着CP水平的增加,每克增重消耗CP量极显著上升(P<0.01),每克增重消耗ME量先降低后升高(P<0.01)。2)CP水平对食入氮、粪尿氮、氮利用率、GE代谢率有极显著影响( P<0.01),ME水平对粪尿氮、氮利用率、粪尿GE和GE代谢率有显著(P<0.05)或极显著(P<0.01)的影响,CP和ME水平的互作对食入氮、食入GE、粪尿GE、ME有显著(P<0.05)或极显著(P<0.01)的影响。由此可知,4~8周四川白鹅适宜的CP水平为15%,ME水平为12.13 MJ/kg。%This experiment was conducted to study the effects of crude protein(CP) and metabolizable energy(ME) levels on performance and nitrogen balance of Sichuan white geese aged from 4 to 8 weeks. Five hun-dred and forty healthy 22-day-old China Sichuan white geese with similar body weight were used in a 3 × 3 double factorial design trial and randomly allocated into 9 groups with 4 replicates in each group and 15 geese in each replicate. The geese were fed 9 experimental diets with three levels of ME(12. 86, 12. 13 and 11.43 MJ/kg) and three levels of CP(17%, 15% and 13%). The feeding experiment lasted for 35 days. Eight geese per group were picked up on the basis of individual weight immediate to the average weight of ev-ery group on day 21 of the experiment, and the geese were used in

  1. Effects of chop length and ensiling period of forage maize on in vitro rumen fermentation characteristics

    OpenAIRE

    Cone, J.W.; Gelder, De; Schooten, van, H.A.

    2008-01-01

    The effect of chop length and ensiling period on in vitro rumen fermentation characteristics of forage maize was studied in two experiments. In the first experiment, maize plants of eight cultivars representing different combinations of Dry Down, Stay Green, early ripening, late ripening, starch and cell wall types were chopped at harvest into pieces of 6 or 15 mm and ensiled in small laboratory silos. After 8 weeks, silage samples were taken and freeze-dried (not ground) before in vitro rume...

  2. Worker participation - the Netherlands

    NARCIS (Netherlands)

    Kwantes, J.H.

    2014-01-01

    Worker participation relates to the involvement of workers in the management decision-making processes. In this article attention is focused on worker participation related to occupational safety and health in the Netherlands. Worker participation can refer either to direct or indirect participation

  3. The Effect of 8-week Soccer Exercise wi th Medium Intensi ty on Executive Function in Preschool Children%8周中等强度足球运动游戏对学龄前儿童执行功能发展的影响

    Institute of Scientific and Technical Information of China (English)

    江大雷; 曾从周

    2015-01-01

    Objective :To investigate the effect of soccer exercise on executive function and its sub components on preschool children aged 5~6 .Methods :61 children selected as subjects of this study ,were randomly divided into control group and experimental group .Experimental group performed soccer exercise with moderate intensity ,35 minutes each time ,two times a week for 8 weeks ,exercise was controlled for heart rate (HR) .Physical fitness and executive function were measured before and after the experiment .Executive function test included inhib‐itory control (Panda‐Lion task and Snow‐Grass task ) ,working memory (The Corsi Blocks Test and The reverse Corsi Blocks Test ) and cognitive flexibility (Flexible Item Selection Task) .Results :Scores of executive function and inhibitory control in the experimental group are significantly higher than that of control group (P<0 .05) ,and no difference in other inde‐xes .Time and group have significant interaction on scores of executive function and inhibitory control and cognitive flexibility .Conclusion :8‐week soccer exercise can improve the children's executive function ,especially inhibitory control .%目的:探讨足球运动游戏对5~6岁学龄前儿童执行功能及3个维度发展的影响。方法:选取学龄前儿童61人作为被试,随机分为对照组30人和实验组31人,实验组进行中等强度足球运动游戏,每次35 min ,每周2次,共8周,通过心率控制运动强度。实验前、后测定身体素质和执行功能,执行功能测查包括抑制控制(熊猫‐狮子任务和雪地‐绿草任务)、工作记忆(科斯积木和反科斯积木任务)和认知灵活性(项目灵活选择任务)。结果:实验组儿童执行功能总分和抑制控制得分显著高于对照组(P<0.05),而其余指标无显著性差异。时间和组别在执行功能总分及抑制控制和认知灵活性上有显著的交互作用。结论:8周足球运动

  4. Requirements of Crude Protein and Metabolizable Energy of Male China Micro-Duck Aged from 4 to 8 Weeks%4~8周龄中畜小型白羽肉鸭公鸭粗蛋白质和代谢能需要量的研究

    Institute of Scientific and Technical Information of China (English)

    汪水平; 彭祥伟; 解华东

    2013-01-01

    This experiment was conducted to study the requirements of crude protein (CP) and metabolizable energy (ME) of male China micro-duck (CMD) ducks aged from 4 to 8 weeks.Five hundred and forty healthy 19-day-old male CMD ducks with similar body weight were used in a 3 × 3 double factorial design trial and randomly allocated into 9 groups with 4 replicates in each group and 15 ducks in each replicate.The ducks were fed 9 experimental diets with three levels of CP (20%,18% or 16%) and ME (12.92,12.19 or 11.49 MJ/kg).The feeding experiment lasted for 38 days,the duration of the preliminary experiment was from 1 to 3 days and the duration of the formal experiment was from 4 to 38 days.Ten ducks per group were chosen on the basis of individual weight close to the average weight of every group on 25 days of the experiment,and the ducks were used in a metabolism trial.At 07:00 on 4 days of the experiment before feeding,one duck per group were chosen on the basis of weight close to the average weight of every group,and those ducks were slaughtered in a comparative slaughter experiment.The results showed as follows:with the increase of dietary CP level,the daily gain and the daily dry matter intake were significantly increased (P < 0.05 or P <0.01),and the ratio of feed to gain was significantly decreased (P <0.01) ; with the increase of dietary ME level,the daily gain was significantly increased (P < 0.01),and the ratio of feed to gain was significantly decreased (P < 0.01) ; the interaction between dietary CP and ME levels was significant in the growth performance (P < 0.01) ; with the increased level of dietary ME level,the availability of gross energy was significantly increased (P < 0.05) ; the interaction between dietary CP and ME levels was significant in the availability of nitrogen and gross energy (P <0.01) ; the deposition rates of ME or CP were significantly increased with the increase of dietary CP or ME levels (P <0.05 or P <0

  5. User participation in implementation

    DEFF Research Database (Denmark)

    Fleron, Benedicte; Rasmussen, Rasmus; Simonsen, Jesper

    2012-01-01

    Systems development has been claimed to benefit from user participation, yet user participation in implementation activities may be more common and is a growing focus of participatory-design work. We investigate the effect of the extensive user participation in the implementation of a clinical...... system by empirically analyzing how management, participating staff, and non-participating staff view the implementation process with respect to areas that have previously been linked to user participation such as system quality, emergent interactions, and psychological buy-in. The participating staff...... experienced more uncertainty and frustration than management and non-participating staff, especially concerning how to run an implementation process and how to understand and utilize the configuration possibilities of the system. This suggests that user participation in implementation introduces a need...

  6. Connecting Participant Observation Positions

    DEFF Research Database (Denmark)

    McCurdy, Patrick; Uldam, Julie

    2014-01-01

    In this article, we argue for the importance of considering participant observation roles in relation to both insider/outsider and overt/covert roles. Through combining key academic debates on participant observation, which have separately considered insider/outsider and overt/covert participant...... observation, we develop a reflexive framework to assist researchers in (1) locating the type of participant observation research; (2) identifying implications of participant observation for both the research and the subjects under study; and (3) reflecting on how one’s role as participant observer shifts over...

  7. Participation and agency

    DEFF Research Database (Denmark)

    Jamison, Andrew

    2004-01-01

    The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe.......The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe....

  8. Labor Force Participation Rate

    Data.gov (United States)

    City and County of Durham, North Carolina — This thematic map presents the labor force participation rate of working-age people in the United States in 2010. The 2010 Labor Force Participation Rate shows the...

  9. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Z > Participating in Clinical Trials: About Clinical Trials In This Topic About Clinical Trials Risks and Benefits ... of this page please turn Javascript on. Participating in Clinical Trials About Clinical Trials A Research Study ...

  10. Participation and agency

    DEFF Research Database (Denmark)

    Jamison, Andrew

    2004-01-01

    The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe.......The article adresses the gap between the rhetoric and practice of participation in urban environmental planning in Europe....

  11. Participation in adult learning

    DEFF Research Database (Denmark)

    Desjardins, Richard

    2010-01-01

    This entry presents an internationally comparative overview of adult learning patterns. Emphasis is placed on who is participating in adult learning and the observed unequal chances to participate. The entry covers three overarching questions that are central to participation research: a) What...

  12. Displacement Through Participation

    NARCIS (Netherlands)

    Huisman, Carla

    2014-01-01

    Citizen participation is often regarded as a means to increase local democracy. Seldom is participation viewed as a means to legitimate disruptive practices of states. However, participation can become a tool for the effective implementation of policy rather than a means to enhance justice, if no po

  13. Mapping eParticipation

    DEFF Research Database (Denmark)

    Rose, Jeremy; Sanford, Clive Carlton

    2007-01-01

    The emerging research area of eParticipation can be characterized as the study of technology-facilitated citizen participation in (democratic) deliberation and decision-making. Using conventional literature study techniques, we identify 105 articles that are considered to be highly relevant to eParticipation......, and methods. We extend the analysis to define four central research challenges for the field: understanding technology and participation; the strategic challenge; the design challenge; and the evaluation challenge. This article thus contributes to a developing account of eParticipation, which will help future...

  14. 语言诱导结合古琴音乐用于原发性失眠的随机对照研究%Hypnotic suggestion combined with Guqin music in the treatment of primary insomnia-a 8-week randomized controlled trial

    Institute of Scientific and Technical Information of China (English)

    风美茵; 汪卫东

    2013-01-01

    insomnia and screened successfully into 3 groups to enter an 8-week intervention in random.Therapeutic effects were assessed on the 0th,4th and 8th at clinics to evaluate efficacy and safety.Patients were assigned in random into the hypnotic suggestion group,the hypnotic suggestion with Guqin music group and the control group for listening of intervention respectively.Athens insomnia scale (AIS),Self-reporting Inventory (SCL-90) and Heart Rate Variability (HRV) were used as the therapeutic indexes.Safety evaluation included change in vital signs,and medical examination before and after treatment.Results Hypnotic suggestion group had lower AIS scores,AIS total (8.70± 4.50),(7.20± 4.40) and the hypnotic suggestion with Guqin music group had lower AIS scores,AIS total (7.30±3.30),(6.80±2.60) were also significantly lowered than the c ontrol group [AIS total (10.30±5.10),(9.80± 5.00) after four-week and eight-week intervention (P< 0.05).The hypnotic suggestion group,indicated a decline in "terror" of SCL-90 scores,SCL-90 total (-0.20±0.60),(0.00±0.60) and the hypnotic suggestion with Guqin music group also indicated a decline in "terror" of SCL-90 scores,SCL-90 total (-0.20±0.50),(-0.20±0.50) when comparing to the control group,SCL-90 total (0.00±0.20),(0.10±0.30).After four-week and eight-week intervention (P<0.05).Percentage Very Low Frequency (VLFper),Percentage High Frequency (HFper) and LF/HF indicated an improvement on average (P<0.05).Conclusion Hypnotic suggestion and combination of hypnotic suggestion with Guqin music in the treatment of primary insomnia,both improve the patient's symptoms such as insomnia and alleviate their "terror"psychological disorders,and can help some insomnia to stop using sleeping pills.

  15. Determinants of resumption of vaginal intercourse in puerperium period in Ogbomoso: consideration for early use of contraceptives

    Directory of Open Access Journals (Sweden)

    Kola M. Owonikoko

    2014-08-01

    Full Text Available Background: Early postpartum period for mothers is characterized with high demand for neonatal care, adjusting to sudden withdrawal of hormones of pregnancy and dealing with sexual desires of the husband. The study aimed at determines the timing, factors influencing postpartum resumption of vaginal intercourse and the contraceptive usage. Methods: Women in puerperium were interviewed with structured questionnaire on their socio-demographic status, obstetric history, sexual activities, contraception usage and reason for sexual abstinence. Results: About 40% (143 of participants had resumed vaginal intercourse within puerperium with mean resumption period of 3.2 +/- 1.8 weeks. Only 12% (48 of them used modern contraceptive. Educational status (P <0.001; occupation (P <0.001; educational status of the husband (P <0.001; occupation of the husband (P <0.001; parity (P <0.05; husband's income (P <0.05 and use of modern contraception (P <0.001 showed significant statistical difference between the women who had resumed vaginal sexual intercourse and those who have not. Logistic regression showed that educational status of the participants (OR = 0.48, CI = 0.246-0.938; P = 0.032 and parity (OR = 0.34, CI = 0.196-0.591; P = 0.001 were the most significant factors associated with early resumption of vaginal intercourse. One hundred and eighty-five (72% of women who were yet to resume coitus, did so because of fear of pregnancy. Conclusions: Significant number of women resumed vaginal intercourse during the puerperium despite low contraception usage. There is need to initiate a contraception method before discharge home following delivery. [Int J Reprod Contracept Obstet Gynecol 2014; 3(4.000: 1061-1066

  16. The body participating:

    DEFF Research Database (Denmark)

    Pallesen, Hanne; Lund, Lone Blak; Jensen, Marianne

    2017-01-01

    ABSTRACT Background: The literature on participation in rehabilitation by those with the most severe acquired brain injury is very sparse. Objectives: The aim of this study was to explore how physiotherapists promote the participation of patients with severe brain injury in therapeutic and daily-...... and low level of consciousness in terms of their participation and functioning in everyday life.......-based analyses. The results were theoretically stated and supported. Results: In an effort to achieve patient participation, the following four themes seemed to be significant: 1) consciously encountering the patient in the moment, 2) the employment of concepts surrounding the interaction between body...

  17. Observing participating observation

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2011-01-01

    Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming...... as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation....

  18. Observing participating observation

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2010-01-01

    Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming...... as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation....

  19. Sense of participation

    NARCIS (Netherlands)

    Bohorques Montemayor, L.; Nevejan, C.I.M.; Brazier, F.M.

    2013-01-01

    This paper explores the sense of participation of a spatially distributed individual—in the intersections of physical and mediated networks. This sense is fundamental to an individuals’ experience as a participant in systems designed to this purpose including today’s social media and new media gener

  20. Outdoor recreation participation trends

    Science.gov (United States)

    H. Ken Cordell; Barbara L. McDonald; R. Jeff Teasley; John C. Bergstrom; Jack Martin; Jim Bason; Vernon R. Leeworthy

    1999-01-01

    As part of the national assessment of outdoor recreation trends, the authors have taken a look at participation patterns and levels of participation across activities and across segments of our society. The primary source of data is the National Survey on Recreation and the Environment (NSRE). The NSRE is the latest in the continuing series of National Recreation...

  1. Sense of participation

    NARCIS (Netherlands)

    Bohorques Montemayor, L.; Nevejan, C.I.M.; Brazier, F.M.

    2013-01-01

    This paper explores the sense of participation of a spatially distributed individual—in the intersections of physical and mediated networks. This sense is fundamental to an individuals’ experience as a participant in systems designed to this purpose including today’s social media and new media

  2. Participation beyond observation

    DEFF Research Database (Denmark)

    Chimirri, Niklas Alexander

    , however, the researchers typically uphold the notion that all they methodically engage in is participant observation. The paper argues that important aspects of children’s living and understanding may be lost when considering them mere objects of one’s visual and verbal research practices. First I delve...... on investigating children’s perspectives through participant observation, but also ontological and political ones....

  3. Financial Participation of Employees in Latvia

    DEFF Research Database (Denmark)

    Klauberg, Theis; Muravska, Tatyana; Mygind, Niels

    2006-01-01

    This report outlines main trends in employees' financial participation in Latvia including historical, socioeconomic and legal background. A special emphasis is placed on privatization during the transition period which shaped an environment for employees' financial participation and influenced...... the current state of employee share ownership and profit-sharing. Attitudes of social partners and the government will be addressed. The report will show why the transition process lead to a low level of employees' financial participation and the indifference and ignorance of policy makers concerning...... the development of financial participation....

  4. Financial Participation of Employees in Latvia

    DEFF Research Database (Denmark)

    Klauberg, Theis; Muravska, Tatyana; Mygind, Niels

    2006-01-01

    This report outlines main trends in employees' financial participation in Latvia including historical, socioeconomic and legal background. A special emphasis is placed on privatization during the transition period which shaped an environment for employees' financial participation and influenced...... the current state of employee share ownership and profit-sharing. Attitudes of social partners and the government will be addressed. The report will show why the transition process lead to a low level of employees' financial participation and the indifference and ignorance of policy makers concerning...... the development of financial participation....

  5. Depression and Political Participation*

    Science.gov (United States)

    Ojeda, Christopher

    2015-01-01

    In this paper, I propose that depression is a political phenomenon insofar as it has political sources and consequences. I then investigate one aspect of this argument—whether depression reduces participation. I hypothesize that individuals with depression lack the motivation and physical capacity to vote and engage in other forms of political participation due to somatic problems and feelings of hopelessness and apathy. Moreover, I examine how depression in adolescence can have downstream consequences for participation in young adulthood. The analyses, using both cross-sectional and longitudinal data, show that voter turnout and other forms of participation decrease as the severity of depressed mood increases. These findings are discussed in light of disability rights and potential efforts to boost participation among this group. PMID:26924857

  6. Depression and Political Participation.

    Science.gov (United States)

    Ojeda, Christopher

    2015-11-01

    In this paper, I propose that depression is a political phenomenon insofar as it has political sources and consequences. I then investigate one aspect of this argument-whether depression reduces participation. I hypothesize that individuals with depression lack the motivation and physical capacity to vote and engage in other forms of political participation due to somatic problems and feelings of hopelessness and apathy. Moreover, I examine how depression in adolescence can have downstream consequences for participation in young adulthood. The analyses, using both cross-sectional and longitudinal data, show that voter turnout and other forms of participation decrease as the severity of depressed mood increases. These findings are discussed in light of disability rights and potential efforts to boost participation among this group.

  7. Observing participating observation

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2011-01-01

    Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming...... a participant and, as such, co-producer of the observed phenomenon. There is no such thing as a neutral or objective description. As observation deals with differences and process meaning, all descriptions are reconstructions and interpretations of the observed. Hence, the idea of neutral descriptions as well...... as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation....

  8. Observing participating observation

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2010-01-01

    Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming...... a participant and, as such, co-producer of the observed phenomenon. There is no such thing as a neutral or objective description. As observation deals with differences and process meaning, all descriptions are re-constructions and interpretations of the observed. Hence, the idea of neutral descriptions as well...... as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation....

  9. Medicare Program; hospital inpatient prospective payment systems for acute care hospitals and the long-term care hospital prospective payment system changes and FY2011 rates; provider agreements and supplier approvals; and hospital conditions of participation for rehabilitation and respiratory care services; Medicaid program: accreditation for providers of inpatient psychiatric services. Final rules and interim final rule with comment period.

    Science.gov (United States)

    2010-08-16

    : We are revising the Medicare hospital inpatient prospective payment systems (IPPS) for operating and capital-related costs of acute care hospitals to implement changes arising from our continuing experience with these systems and to implement certain provisions of the Affordable Care Act and other legislation. In addition, we describe the changes to the amounts and factors used to determine the rates for Medicare acute care hospital inpatient services for operating costs and capital-related costs. We also are setting forth the update to the rate-of-increase limits for certain hospitals excluded from the IPPS that are paid on a reasonable cost basis subject to these limits. We are updating the payment policy and the annual payment rates for the Medicare prospective payment system (PPS) for inpatient hospital services provided by long-term care hospitals (LTCHs) and setting forth the changes to the payment rates, factors, and other payment rate policies under the LTCH PPS. In addition, we are finalizing the provisions of the August 27, 2009 interim final rule that implemented statutory provisions relating to payments to LTCHs and LTCH satellite facilities and increases in beds in existing LTCHs and LTCH satellite facilities under the LTCH PPS. We are making changes affecting the: Medicare conditions of participation for hospitals relating to the types of practitioners who may provide rehabilitation services and respiratory care services; and determination of the effective date of provider agreements and supplier approvals under Medicare. We are also setting forth provisions that offer psychiatric hospitals and hospitals with inpatient psychiatric programs increased flexibility in obtaining accreditation to participate in the Medicaid program. Psychiatric hospitals and hospitals with inpatient psychiatric programs will have the choice of undergoing a State survey or of obtaining accreditation from a national accrediting organization whose hospital accreditation

  10. Measuring Scars of Periodic Orbits

    CERN Document Server

    Kaplan, L

    1999-01-01

    The phenomenon of periodic orbit scarring of eigenstates of classically chaotic systems is attracting increasing attention. Scarring is one of the most important ``corrections'' to the ideal random eigenstates suggested by random matrix theory. This paper discusses measures of scars and in so doing also tries to clarify the concepts and effects of eigenfunction scarring. We propose a new, universal scar measure which takes into account an entire periodic orbit and the linearized dynamics in its vicinity. This measure is tuned to pick out those structures which are induced in quantum eigenstates by unstable periodic orbits and their manifolds. It gives enhanced scarring strength as measured by eigenstate overlaps and inverse participation ratios, especially for longer orbits. We also discuss off-resonance scars which appear naturally on either side of an unstable periodic orbit.

  11. From spectator to participant

    DEFF Research Database (Denmark)

    Hoffmann, Birgitte; Kofoed, Jens

    The book collects experiences and methods for citizens’ participation in order to strengthen the local Agenda 21 process. 5 different types of methods is presented: Methods of analyses and evaluation, methods of dialogue, methods for action, methods for networking, and finely methods for involvin...... local institutions. In the opening part the book deals with fundamental themes in participation processes such as planning of changes and changes and conflicts.......The book collects experiences and methods for citizens’ participation in order to strengthen the local Agenda 21 process. 5 different types of methods is presented: Methods of analyses and evaluation, methods of dialogue, methods for action, methods for networking, and finely methods for involving...

  12. Contact Quality in Participation

    DEFF Research Database (Denmark)

    Simonsen, Jesper; Jensen, Olav Storm

    2016-01-01

    We investigate the concept of participation from the perspective of quality of the contact in the communicative interactions between participants. We argue for the need for an academic-personal competence that qualifies the human contact central in all Participatory Design (PD) activities as a way...... to contribute to “an era of participation.” We describe a contact perspective in PD developed through a collaboration with body-oriented psychotherapeutic research that have specialized experiences in investigating open-minded contact and authentic meetings as body-related experiences....

  13. Participating in Clinical Trials

    Science.gov (United States)

    ... this page please turn Javascript on. Participating in Clinical Trials About Clinical Trials A Research Study With Human Subjects A clinical ... to treat or cure a disease. Phases of Clinical Trials Clinical trials of drugs are usually described based ...

  14. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Usually, trial participants must show signs of the disease or condition before they can join this type of trial. Prevention Trials Click for more information In prevention trials, ...

  15. Limited Denial of Participation

    Data.gov (United States)

    Department of Housing and Urban Development — A Limited Denial of Participation (LDP) is an action taken by a HUD Field Office or the Deputy Assistant Secretary for Single Family (DASSF) or Multifamily (DASMF)...

  16. Putting Participation into Practice

    African Journals Online (AJOL)

    Keywords: participatory action research, primary care, mutual participation ... a mutual participatory doctor-patient relationship model, and to apply this ..... Leuner JD, Webster A. Social support, ... Personality and exercise as buffers in the.

  17. Trends in educational participation

    NARCIS (Netherlands)

    B. Kuhry

    1998-01-01

    Original title: Trends in onderwijsdeelname. This study looks at the design, outcomes and administrative manageability of educational forecasts. Historical trends in educational participation and the phenomenon of 'educational expansion' (in which more and more young people follow secondary

  18. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... new tests that could identify a disease in its early stages. Usually, trial participants must show signs ... often healthy people (20 to 80), to judge its safety and side effects, and to find the ...

  19. From spectator to participant

    DEFF Research Database (Denmark)

    Hoffmann, Birgitte; Kofoed, Jens

    The book collects experiences and methods for citizens’ participation in order to strengthen the local Agenda 21 process. 5 different types of methods is presented: Methods of analyses and evaluation, methods of dialogue, methods for action, methods for networking, and finely methods for involving...... local institutions. In the opening part the book deals with fundamental themes in participation processes such as planning of changes and changes and conflicts....

  20. Size and Political Participation

    DEFF Research Database (Denmark)

    Lassen, David Dreyer; Serritzlew, Søren

    This paper uses a novel research design to re-examine the causal effect of jurisdiction size on political participation. Two waves of municipal consolidation in Denmark, in 1970 and in 2005, provide exogenous variation in jurisdiction size.......This paper uses a novel research design to re-examine the causal effect of jurisdiction size on political participation. Two waves of municipal consolidation in Denmark, in 1970 and in 2005, provide exogenous variation in jurisdiction size....

  1. Size and Political Participation

    DEFF Research Database (Denmark)

    Lassen, David Dreyer; Serritzlew, Søren

    This paper uses a novel research design to re-examine the causal effect of jurisdiction size on political participation. Two waves of municipal consolidation in Denmark, in 1970 and in 2005, provide exogenous variation in jurisdiction size.......This paper uses a novel research design to re-examine the causal effect of jurisdiction size on political participation. Two waves of municipal consolidation in Denmark, in 1970 and in 2005, provide exogenous variation in jurisdiction size....

  2. Why Latinas With Breast Cancer Select Specific Informal Caregivers to Participate With Them in Psychosocial Interventions.

    Science.gov (United States)

    Badger, Terry; Segrin, Chris; Swiatkowski, Paulina; McNelis, Melissa; Weihs, Karen; Lopez, Ana Maria

    2017-07-01

    The purpose of this study is to describe the reasons 88 Latinas with breast cancer selected specific supportive others to participate in an 8-week psychosocial intervention. Participants were asked one open-ended question during the baseline assessment for a larger clinical trial: "Could you tell me more about why you selected [insert name] to participate in the study with you?" A content analysis of the responses found three thematic categories: source of informational or emotional support, concern for the informal caregiver's welfare, and special characteristics or qualities of the informal caregiver. These findings reflected both the cultural value of familism, the woman's role as caregiver to the family ( marianismo), and the man's role of provider ( machismo). Findings provide support for including the supportive person identified by the patient during a health crisis rather than the provider suggesting who that should be. Psychosocial services designed and implemented through such a cultural lens are more likely to be successful.

  3. Children's participation in Teledialogue

    DEFF Research Database (Denmark)

    Andersen, Lars Bo; Lauritsen, Peter; Danholt, Peter

    2014-01-01

    Teledialogue is a combined research and design project aimed at improving communications between social workers and children under their custody living in foster care or youth institutions. While social workers are responsible for the welfare of placed children they are under heavy workload...... and often only communicate with children at biannual meetings - the minimum required by law. The purpose of Teledialogue is to use participatory methods to develop an IT-enabled concept for children and social workers to maintain communication between the biannual meetings. Social workers and children...... are thus the primary participants in this design process. This presentation describes the inclusion and participation of the placed children in Teledialogue. With an outset in Actor-Network Theory (ANT) two points are made: 1) that children were participating in shaping the design long before they were...

  4. The participating researcher

    DEFF Research Database (Denmark)

    Hansen, Louise Ejgod

    2014-01-01

    and abilities. The cases will be analyzed with focus on the strategy of participation and the value implications of this for each of them. The second part of the paper will address the role of the researcher as a part of each of these participatory cultural projects as designer, applied researcher, consultant......My paper will focus on the self-reflection of my role as participating researcher in three different art projects all of which have participation as a key element. The paper will begin with a presentation of the three cases: Theatre Talks (Teatersamtaler), Stepping Stones (Trædesten) and Art...... or evaluator. The role of me as a researcher with regard to the development and evaluation of the projects will be analyzed, trying to answer the question: What are the methodological differences between the approaches and how does that affect the research process and results. These differences...

  5. Total design of participation

    DEFF Research Database (Denmark)

    Munch, Anders V.

    2016-01-01

    The idea of design as an art made not only for the people, but also by the people is an old dream going back at least to William Morris. It is, however, reappearing vigoriously in many kinds of design activism and grows out of the visions of a Total Design of society. The ideas of participation...... by Tim Brown can be compared to considerations by László Moholy-Nagy and Walter Gropuis on the training and education of active and capable citizens. This opens, though, some dilemmas to discuss: To what extend is the capability of creativity then a (pre)condition to be a citizen of the society wished...... for? To which degree should everyone be educated in ’design literacy’ to participate? Total design of participation is an artistic intervention in society and must be discussed in this utopian tradition....

  6. Participation and power

    DEFF Research Database (Denmark)

    We would like to welcome you to a series of dialogues within the framework of action research (AR) and participatory research (PR), which will be focused on the relationship between participation and power. The basic question in this anthology is ‘What are the possibilities and barriers to partic......We would like to welcome you to a series of dialogues within the framework of action research (AR) and participatory research (PR), which will be focused on the relationship between participation and power. The basic question in this anthology is ‘What are the possibilities and barriers...... to participation conceptualised as various degrees of codetermination in organisations and in research processes?’ The anthology is part of a follow-up on an initiative taken in 2010 by Professor Werner Fricke, editor-in-chief of the International Journal of Action Research for many years. His vision was to create...

  7. European Patterns of Participation

    DEFF Research Database (Denmark)

    Harrebye, Silas Fehmerling; Ejrnæs, Anders

    2015-01-01

    of dissatisfaction with the government and feelings of being member of a discriminated group affect the level of extra-parliamentary participation, and second, how different welfare regimes condition the extend to which these groups chose to act. In a comparative multilevel design, using data from the European...... Social Survey (ESS) Round 4 (2008), the article finds that satisfaction/dissatisfaction with the government is an important predictor alongside the institutional macro-level variable. The article combines a critical tradition, which suggests that political participation is motivated by a feeling...... of dissatisfaction with an institutional perspective in which certain institutional conditions are seen as enablers for citizens to actively participate in political life. Our results show that the overall level of extra-parliamentary activity in the Scandinavian countries is higher than in the other European...

  8. The Subjectivity of Participation

    DEFF Research Database (Denmark)

    Nissen, Morten

    What is a 'we' – a collective – and how can we use such communal self-knowledge to help people? This book is about collectivity, participation, and subjectivity – and about the social theories that may help us understand these matters. It also seeks to learn from the innovative practices and ideas...... of a community of social/youth workers in Copenhagen between 1987 and 2003, who developed a pedagogy through creating collectives and mobilizing young people as participants. The theoretical and practical traditions are combined in a unique methodology viewing research as a contentious modeling of prototypical...

  9. Participation in physical planning

    Directory of Open Access Journals (Sweden)

    Zlata Ploštajner

    2003-01-01

    Full Text Available Physical planning is also a political activity. Therefore participation is a necessary form of democratic actions undertaken by individuals and groups that strive for democratisation of civil society and strengthening of democratic social values. Public participation of citizens, legal subjects, interest groups and others in physical planning is essential even from the aspect of ensuring success and efficiency of planning documents, if the idea is to devise a plan, which the people would be ready and capable of implementing. Thus the role of the physical planner is changing from technical expert to mediator or anchor-person, who nevertheless has to operate within a normative framework.

  10. Walking. Sensing. Participation

    DEFF Research Database (Denmark)

    Bødker, Mads

    2014-01-01

    This paper uses three meditations to contemplate walking, sensing and participation as three ways with which we can extend the notion of ‘experiential computing’ proposed by Yoo (2010). By using the form of meditations, loosely associated concepts that are part introspective and part ‘causative’, i...

  11. The Subjectivity of Participation

    DEFF Research Database (Denmark)

    Nissen, Morten

    What is a 'we' – a collective – and how can we use such communal self-knowledge to help people? This book is about collectivity, participation, and subjectivity – and about the social theories that may help us understand these matters. It also seeks to learn from the innovative practices and ideas...

  12. Public Participation GIS

    DEFF Research Database (Denmark)

    Hansen, Henning Sten

    2004-01-01

    information in environmental planning and gives an overview over the various approaches to public participation. The current advances in Web-based GIS in many countries contain great possibilities for supporting good governance based on information and knowledge on the one hand and active involvement...

  13. From understanding to participation

    DEFF Research Database (Denmark)

    Raudaskoski, Pirkko Liisa

    2013-01-01

    , multimodal process in which language together with bodily senses (vision, hearing, touch, smell and taste) and a sense of place contribute to a phenomenon being recognized (as shared). Participation can result in inclusion or exclusion, a claim which is discussed with the help of a pilot study from...

  14. Participating in Clinical Trials

    Medline Plus

    Full Text Available skip navigation Help Search home health topics A-Z Videos A-Z about us Customer Support NIH SeniorHealth Built with You in Mind Resize Text: A A A Change Contrast print sign up Share Home > Health topics A-Z > Participating in Clinical Trials: About ...

  15. Lifelong learning and participation

    DEFF Research Database (Denmark)

    Rothuizen, Jan Jaap; Molpeceres, Mariangeles; Hansen, Helle Krogh

    2014-01-01

    and an assumed desire of generativity. Action learning seems to be an appropriate learning concept in relation to keeping older people engaged in the community. The authors thus point at participating and lifelong learning as part of the answers to the demographic challenges, and they suggest what you might call...

  16. Personas, people and participation

    DEFF Research Database (Denmark)

    Bødker, Susanne; Christiansen, Ellen Tove; Nyvang, Tom

    2012-01-01

    use, and personas have been introduced for this purpose. The paper uses research on user participation and research-based personas from the eGov+ project to discuss whether personas help designers engage with users. In this project, design was carried out in the domain of municipal services through...

  17. Communication Games: Participant's Manual.

    Science.gov (United States)

    Krupar, Karen R.

    Using a series of communicational games, the author leads the participant through self-awareness, verbal and nonverbal communication, decision-making, problem-solving, and skills in perception, listening, and small group, organizational, and cultural communications. The thesis behind the book is that model-making, role-playing, or other forms of…

  18. Sport participation styles revisited

    NARCIS (Netherlands)

    Steven Vos; Erik Thibaut; Bart Vanreusel; Julie Borgers; Hanne Vandermeerschen; Jeroen Scheerder

    2013-01-01

    Social changes have been influencing determinants for sports participation since the introduction of the Sport for All ideology in the early 1970s. Consistent with Crum’s sportisation theory, today’s modes of sports practices, as well as the network of sport services, have diversified and

  19. Participation under Uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Boudourides, Moses A. [Univ. of Patras, Rio-Patras (Greece). Dept. of Mathematics

    2003-10-01

    This essay reviews a number of theoretical perspectives about uncertainty and participation in the present-day knowledge-based society. After discussing the on-going reconfigurations of science, technology and society, we examine how appropriate for policy studies are various theories of social complexity. Post-normal science is such an example of a complexity-motivated approach, which justifies civic participation as a policy response to an increasing uncertainty. But there are different categories and models of uncertainties implying a variety of configurations of policy processes. A particular role in all of them is played by expertise whose democratization is an often-claimed imperative nowadays. Moreover, we discuss how different participatory arrangements are shaped into instruments of policy-making and framing regulatory processes. As participation necessitates and triggers deliberation, we proceed to examine the role and the barriers of deliberativeness. Finally, we conclude by referring to some critical views about the ultimate assumptions of recent European policy frameworks and the conceptions of civic participation and politicization that they invoke.

  20. Participation som organisatorisk praksis

    DEFF Research Database (Denmark)

    Jeppesen, Hans Jeppe; Jønsson, Thomas

    2009-01-01

    Hensigten med artiklen er at give et bidrag til forståelsen af begrebet organisatorisk participation både teoretisk og ud fra praksis. Det gøres ud fra analyser og tematiseringer af participationens mangfoldighed, participationssystemers konstituering, participationens substans og finalitet samt...

  1. Evolution of nutritional, hematologic and biochemical changes in obese women during 8 weeks after Roux-en-Y gastric bypasss Evolución de los cambios nutricionales, hematológicos y bioquímicos en mujeres obesas durante 8 semanas después de bypass gástrico en Y de Roux

    Directory of Open Access Journals (Sweden)

    V. Custódio Afonso Rocha

    2012-08-01

    Full Text Available Obesity is a chronic disease of multifactorial origin and currently is a serious public health problem. The treatment of morbid obesity can be effectively done by bariatric surgery. The present study aimed to evaluate the influence of changes in food intake on body composition and some hematologic and biochemical variables in the period of eight weeks after Roux-en-Y gastric bypass (RYGB. The study included 22 women submitted to RYGB. We evaluated anthropometric, nutritional, hematologic and biochemical variables before and 14, 28, 42 and 56 days after surgery. The patients showed a decrease in caloric intake and hence macro- and micronutrients, with significant loss of weight and decrease in body mass index (BMI. Decreases in body weight and BMI were associated with reduced blood levels of total cholesterol, VLDL-C, LDL-C, triglycerides and glucose with time after surgery. The decrease in caloric intake was also associated with decreased intake of protein, iron and calcium, with a decline in hemoglobin, hematocrit and red blood count, and RDW increased after surgery.La obesidad es una enfermedad crónica de origen multifactorial y actualmente es un problema grave de salud pública. El tratamiento de la obesidad mórbida puede hacerse eficazmente por la cirugía bariátrica. El presente estudio tuvo como objetivo evaluar la influencia de los cambios en la ingesta de alimentos sobre la composición corporal y algunas variables hematológicas y bioquímicas en el plazo de ocho semanas después de bypass gástrico en Y de Roux (BGYR. El estudio incluyó a 22 mujeres sometidas a BGYR. Se evaluaron los parámetros antropométricos, nutricionales, bioquímicos antes de la operación y el 14º, 28º, 42º e 56º día después de la cirugía. Los pacientes mostraron cambios significativos en la ingesta de alimentos, con una disminución en la ingesta de calorías y por lo tanto, los macro y micronutrientes, con una pérdida significativa de peso y

  2. Participation in decision making

    Directory of Open Access Journals (Sweden)

    EG Valoyi

    2000-06-01

    Full Text Available The aim of the present study was to determine the extent to which employees would like to participate in decision making concerning various organisational issues, especially those concerning: the work itself, working conditions, human resources issues, and corporate policy and planning. The sample consisted of 146 participants, including managers, middle managers, and junior officials from a South African development corporation. A questionnaire to measure employees' desire to participate in decision making was specially constructed for this investigation. It has found that employees with higher academic qualifications were more desirous to participate in decision-making at all levels than employees with lower academic qualifications. This was also true for employees in higher job grades than in lower job grades. Men were more desirous to participate in decision making than women. The implications of the findings are discussed. Opsomming Die doel van die huidige studie was om vas te stel in watter mate werknemers sal wil deelneem aan die besluit- nameproses van organisasies, veral rakende die volgende sake: die werk self, werksomstandighede, menslike hulpbronaangeleenthede en korporatiewe beleid en beplanning. Die steekproef het uit 146 deelnemers, insluitende bestuurders, middelvlakbestuurders en junior amptenare van'n Suid Afrikaanse ontwikkelingskorporasie, bestaan. nVraelys wat die begeerte van werknemers meet om aan die besluitnameproses deel te neem, is spesiaal vir die doel van hierdie ondersoek, ontwerp. Dit is bevind dat werknemers met hoer akademiese kwalifikasies meer begerig is om aan die besluitnameproses op alle vlakke deel te neem as werknemers met laer akademiese kwalifikasies. Dit was ook waar vir werknemers in hoervlakposte vergeleke met werknemers in laervlakposte. Mans was ook meer begerig om aan die besluitnameproses deel te neem as vroue. Die implikasies van die studie word bespreek.

  3. Sports participation with Chiari I malformation.

    Science.gov (United States)

    Strahle, Jennifer; Geh, Ndi; Selzer, Béla J; Bower, Regina; Himedan, Mai; Strahle, MaryKathryn; Wetjen, Nicholas M; Muraszko, Karin M; Garton, Hugh J L; Maher, Cormac O

    2016-04-01

    OBJECT There is currently no consensus on the safety of sports participation for patients with Chiari I malformation (CM-I). The authors' goal was to define the risk of sports participation for children with the imaging finding of CM-I. METHODS A prospective survey was administered to 503 CM-I patients at 2 sites over a 46-month period. Data were gathered on imaging characteristics, treatment, sports participation, and any sport-related injuries. Additionally, 81 patients completed at least 1 subsequent survey following their initial entry into the registry and were included in a prospective group, with a mean prospective follow-up period of 11 months. RESULTS Of the 503 CM-I patients, 328 participated in sports for a cumulative duration of 4641 seasons; 205 of these patients participated in contact sports. There were no serious or catastrophic neurological injuries. One patient had temporary extremity paresthesias that resolved within hours, and this was not definitely considered to be related to the CM-I. In the prospective cohort, there were no permanent neurological injuries. CONCLUSIONS No permanent or catastrophic neurological injuries were observed in CM-I patients participating in athletic activities. The authors believe that the risk of such injuries is low and that, in most cases, sports participation by children with CM-I is safe.

  4. Participating in patient education

    DEFF Research Database (Denmark)

    Kristiansen, Tine Mechlenborg; Antoft, Rasmus

    2015-01-01

    The paper builds on previous ethnographic research in Denmark focusing on the significance of participating in a locally developed patient education programme for everyday life (Kristiansen et.al. 2015). It presents a secondary analysis. Group based patient education can be understood as a health...... point is applied in order to illustrate two central status passages taking place at the locally developed patient education programme: 1) The status passage from novice to an experienced person with chronic illness, and 2) The transformation from adolescence to adulthood living with a chronic illness....... Related to both status passages we analyse how the central properties of status passage are at play and how they are shaped by the social interactions among the different agents: participants, lay experts and health professionals. We discuss how the theory of status passage might further enrich empirical...

  5. Poverty, health and participation.

    Science.gov (United States)

    Cosgrove, S

    2007-09-01

    Poverty is an important influence on health and despite continuing economic growth, poverty and health inequalities persist. Current public policy aims to reduce the inequalities in the health, by focussing on the social factors influencing health, improving access to health and personal social services for those who are poor or socially excluded and by improving the information and research base in respect of the health status and service access for the poor and socially excluded groups. It is important that processes for target setting and evaluation involve people experiencing poverty, at all levels through consultative and participative structures and processes and in the roll-out of primary care teams. A number of projects throughout the country aim to address health inequalities using community development. These are essentially about widening participation in the development, planning and delivery of health services and ensuring that the community is actively involved in the decision making process about health services in their area.

  6. Invited to Participate?

    DEFF Research Database (Denmark)

    Nielsen, Karen Dam

    This thesis presents an ethnography of e-health and patient participation in heart care. Drawing on Science & Technology Studies (STS) and Computer Supported Cooperative Work (CSCW), the thesis goes beyond the common narrative of e-health as a solution and vehicle for transforming healthcare......-involving e-health: ‘participatory scopic devices‘, ‘dialogic filtration work‘, and ‘participatory tactics‘. In particular, these concepts add to the analytics of STS and CSCW for studying sociotechnical reconfigurations of healthcare. However, the concepts may also inform the wider field of research into e......-health and patient participation. The fourth paper moves beyond the explorative research aim and translates the ethnographic insights from the user test into a design rationale for patient-involving e-health. The proposed design rationale stresses analytical attention to the situated and diverging concerns among...

  7. Involvement Without Participation?

    DEFF Research Database (Denmark)

    Olsén, Peter

    2012-01-01

    The article presents a case study of a knowledge-intensive company that launched a 2-year project to improve their psychosocial working environment. All parties agreed on the project, and the methods used aimed to promote the involvement of the employees. Surprisingly, the psychosocial working...... and participation. In order to develop a more sustainable and viable psychosocial working environment, a broader and more democratic notion of organisational learning and managing is proposed....

  8. Participating in Poltics

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    NOW that I am a member of the Ninth National Committee of the Chinese People’s Political Consultative Conference (CPPCC), I feel the heavy weight of responsibility on my shoulders. As an editor of Women of China, however, I feel honored to have been chosen for this role. The CPPCC is an important institution which gives people from all walks of life the opportunity to participate in state

  9. Governability and Citizen Participation

    Directory of Open Access Journals (Sweden)

    Giancarla de Quiroga

    1999-10-01

    Full Text Available bjective conditions that allow for a harmonic relationship between the governors and the governed. We are speaking about a set of conditions for governing by consensus and in harmony. By “citizen participation” we refer to the fact that citizens share in the powerof decision over something that concerns them. In Bolivia, as well in other Latin American countries, citizenship participation in municipal management is a recent phenomena. This article describes the experience of citizenry participation in the municipality ofCochabamba (Bolivia in relation to quality of life and living conditions in a neighborhood. The municipality of Cochabamba has embarked upon a mission of rescue and evaluation of the neighborhood organizations, not only incorporating the population into the processes of participation, but also acting in favor of social integration because this stresses the commitment of the neighborhood citizens in the design of the plans. In conclusion, the unfolding experience in the municipality of Cochabamba makes the fact clear that beyond the concept of governability, the search for a co-government-type relation prevails, one that is more horizontal and equitable and where the population takes on a leading role for bringing about the social cohesion and the sense of belonging needed to face the serious problems that afflict Latin American cities.

  10. IMPACT OF MASS MEDIA ON ELECTORAL PARTICIPATION

    OpenAIRE

    Ion MOCANU; Reviewer: Vladimir BLAJCO

    2013-01-01

    In the article is reflected the trust of the population in different types of mass information sources, is analysed the activity of the mass media in the electoral period, is established the influence of mass media on the population and its capacity to mobilize the electoral participation

  11. Impact of mass media on electoral participation

    OpenAIRE

    Mocanu Ion

    2013-01-01

    In the article is reflected the trust of the population in different types of mass information sources, is analysed the activity of the mass media in the electoral period, is established the influence of mass media on the population and its capacity to mobilize the electoral participation

  12. Inverse periodic shadowing properties

    CERN Document Server

    Osipov, Alexey V

    2011-01-01

    We consider inverse periodic shadowing properties of discrete dynamical systems generated by diffeomorphisms of closed smooth manifolds. We show that the $C^1$-interior of the set of all diffeomorphisms having so-called inverse periodic shadowing property coincides with the set of $\\Omega$-stable diffeomorphisms. The equivalence of Lipschitz inverse periodic shadowing property and hyperbolicity of the closure of all periodic points is proved. Besides, we prove that the set of all diffeomorphisms that have Lipschitz inverse periodic shadowing property and whose periodic points are dense in the nonwandering set coincides with the set of Axiom A diffeomorphisms.

  13. Your First Period

    Science.gov (United States)

    ... Events Advocacy For Patients About ACOG Your First Period (Especially for Teens) Home For Patients Search FAQs ... Teens) FAQ049, May 2015 PDF Format Your First Period (Especially for Teens) Especially For Teens What is ...

  14. Middle Helladic Period

    DEFF Research Database (Denmark)

    Sarri, Kalliopi

    1999-01-01

    The Middle Bronze Age on Mainland Greece is also known as the Middle Helladic period. The chronological framework of this period extends from the beginnings of the second millenium - roughly 1900 - until 1550 BC, that is until the beginnings of the Mycenaean period. The Middle Helladic period...... is considered as the dark period of the cultural decline. The remains of the material culture reveal a clear retrogression while the information available on the social stratification and economy are so few and problematic in interpretation that this period is considered as the "Middle Age of Greek Prehistory......". About 1900 BC, the period during which the first palaces of Crete were being built, Mainland Greece was entering a long period of decline during which economic features changed radically. A large number of metals and imported products became particularly rare while composite forms of economic...

  15. ON PERIODIC DYNAMICAL SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    LU WENLIAN; CHEN TIANPING

    2004-01-01

    The authors investigate the existence and the global stability of periodic solution for dynamical systems with periodic interconnections, inputs and self-inhibitions. The model is very general, the conditions are quite weak and the results obtained are universal.

  16. Assessing Community Participation: Comparing Self-Reported Participation Data with Organizational Attendance Records.

    Science.gov (United States)

    Christens, Brian D; Speer, Paul W; Peterson, N Andrew

    2016-06-01

    How well do self-reported levels of community and organizational participation align with recorded acts of community and organizational participation? This study explores this question among participants in social action community organizing initiatives by comparing responses on a community participation scale designed to retrospectively assess community participation (T1, n = 482; T2, n = 220) with individual participants' attendance records in various social action organizing activities over two 1-year periods. By testing the self-reported measure's overall and item-by-item association with documented participation in various types of organizing activities, we find that the self-report measure is positively, but weakly correlated with actual participation levels in community organizing activities. Moreover, associations between self-report and recorded acts of participation differ by types of activity. Examining this unique source of data raises important questions about how community participation is conceptualized and measured in our field. Implications are explored for theory and measurement of participation in community and organizational contexts.

  17. Community College Periodicals.

    Science.gov (United States)

    Pederson, Eldor O.

    Drawing from an examination of community college periodicals, their availability and characteristics, the academic affiliations of contributing authors, and the topics of their articles, this paper discusses the minor role which community college periodicals appear to play. A list of 35 periodicals dealing primary with community college education…

  18. Few period quasisymmetric stellarators

    Energy Technology Data Exchange (ETDEWEB)

    Isaev, M.Y.; Mikhailov, M.I.; Shafranov, V.D.; Subbotin, A.A. [Russian Research Centre `Kurchatov Institute`, Moscow (Russian Federation); Cooper, W.A. [Ecole Polytechnique Federale, Lausanne (Switzerland). Centre de Recherche en Physique des Plasma (CRPP); Medvedev, S.Y. [Keldysh Inst. of Applied Mathematics, Russian Academy of Sciences, Moscow (Russian Federation)

    1997-06-01

    The results of plasma equilibrium and local stability investigations in two and four-period quasisymmetric stellarators are presented. A near-axis approximation is used for 2-period systems and the 3D codes VMEC and TERPSICHORE are used for four-periods devices to optimise the configurations. (author) 4 figs., 8 refs.

  19. The Periodic Pyramid

    Science.gov (United States)

    Hennigan, Jennifer N.; Grubbs, W. Tandy

    2013-01-01

    The chemical elements present in the modern periodic table are arranged in terms of atomic numbers and chemical periodicity. Periodicity arises from quantum mechanical limitations on how many electrons can occupy various shells and subshells of an atom. The shell model of the atom predicts that a maximum of 2, 8, 18, and 32 electrons can occupy…

  20. Walking - Sensing - Participation

    DEFF Research Database (Denmark)

    Bødker, Mads; Meinhardt, Nina Dam; Browning, David

    Building on ethnographic research and social theory in the field of ‘mobilities’, this workshop paper suggests that field work based on simply walking with people entails a form of embodied participation that informs technological interventions by creating a space within which to address a wider ...... set of experiential or ‘felt’ qualities of living with mobile technologies. Moving from reflections on the value of walking with people, the paper outlines some affordances of a smartphone application built to capture place experiences through walking....

  1. Participation for Development

    DEFF Research Database (Denmark)

    Dittrich, Yvonne; De La Harpe, Retha; Korpela, Mikko

    2014-01-01

    Information and Communication Technology (ICT) is more and more promoted as a driver and facilitator of economic growth and development in low and middle income countries. ICT for Development (ICT4D) though has mixed successes. Sustainability of solutions and usability respectively usefulness...... is rare. The workshop aims at bringing together the PD researchers working with under-privileged communities and attracting researchers from the ICT4D communities to the PD conference. The goal is to share experiences and start a discussion on how participation, ICT and development might relate....

  2. Cultural participation in Europe

    DEFF Research Database (Denmark)

    Stevenson, David; Kann-Rasmussen, Nanna; Balling, Gitte

    2015-01-01

    Europe has a ‘problem’; it is becoming a ‘less cultural continent’ as fewer Europeans are ‘engaging in cultural activities’. This conclusion has been reached due to the findings of the latest cross national cultural participation survey. This paper questions the existence of this ‘problem......’ and instead suggests that there is a shared problematisation across Europe sustained by common discursive archaeology that employs various discursive strands in relation to a dominant institutional discourse. The argument is that the ‘problem’ of ‘non-participation’ legitimates a ‘solution’ that predates its...

  3. [Women's participation in science].

    Science.gov (United States)

    Sánchez-Guzmán, María Alejandra; Corona-Vázquez, Teresa

    2009-01-01

    The participation of women in higher education in Mexico took place in the late 19th and early 20th century. The rise of women's enrollment in universities known as the "feminization of enrollment" occurred in the last thirty years. In this review we analyze how the new conditions that facilitated better access to higher education are reflected in the inclusion of women in science. We include an overview of the issues associated with a change in the demographics of enrollment, segregation of academic areas between men and women and participation in post graduate degrees. We also review the proportion of women in science. While in higher education the ratio between male and women is almost 50-50 and in some areas the presence of women is even higher, in the field of scientific research women account for barely 30% of professionals. This is largely due to structural conditions that limit the access of women to higher positions of power that have been predominantly taken by men.

  4. Spaceflight participant visits CERN!

    CERN Document Server

    Kathryn Coldham

    2016-01-01

    On 15 July, CERN welcomed spaceflight participant Anousheh Ansari.   Anousheh Ansari’s grin stretches from ear to ear, during an intriguing conversation with Nobel laureate Samuel C.C. Ting at AMS POCC. (Image: Maximilien Brice/CERN) Iranian-American Anousheh Ansari was the first-ever female spaceflight participant, spending eight days on the International Space Station (ISS) in 2006. She now has a new addition to her list of extraordinary sights ­– the home of the world’s largest particle accelerator: CERN.   On 15 July, Anousheh Ansari came to CERN and, unsurprisingly, visited the control room of the experiment attached to the ISS: the AMS. At the AMS Payload Operations Control Centre (AMS POCC) on CERN’s Prévessin site, she met the Nobel laureate Samuel Ting, spokesperson of the AMS experiment. Ansari and her accompanying guests were thrilled to expand their knowledge about CERN, its research and its...

  5. The Participation Decision Study

    Directory of Open Access Journals (Sweden)

    Margaret Y. Ficaj

    2014-02-01

    Full Text Available The 2011 participation decision study involved exploration into the impact of the external education environment on the decision for private school participation in Federal funding, one deliberately declining player in the No Child Left Behind Act of 2001(NCLB choice and competition equation. In the qualitative collective case, three religiously triangulated Michigan private school decision-makers submitted to semi-structured interviews. Analysis of the external environmental factors was through the lens of Gould and Eldredge’s (1977 environmentally oriented theory, punctuated equilibria philosophy of change. Analysis involved layering, direct interpretation, categorical aggregation, and cross-comparison of two external environmental categories identified at literature review (NCLB-content and privatization-dynamic with numerous major and sub-groupings and space for newly emergent material. The category privatization-dynamics emerged as significant influence, as did the major theme trust and the sub-themes motivational intent, competency, consistency, grapevine, creativity or inspiration, restrictions on curriculum, lack of awareness of opportunities available, and fear of failure. The study included five specific recommendations for leaders of change to explain, predict, and improve organizational performance toward greater synchronization in operation of the NCLB choice and competition mechanisms.

  6. PARTICIPANTS IN INSOLVENCY

    Directory of Open Access Journals (Sweden)

    RARES-SEBASTIAN PUIU-NAN

    2012-05-01

    Full Text Available The article examines the officials and other participants in insolvency. The main purpose of the insolvency procedure is to cover all the debts of the debtor side, in favor of his creditor side. The most important regulations regarding this issue consist in Law no. 85/2006, according to it in the insolvency procedure are to be appointed the following officials: insolvency courts of justice, insolvency judge, receiver, liquidator. All these officials have to act in celerity, in order to promptly perform acts and operations provided by law and to respect and provide other participants’ rights and obligations. My article present in the beginning the insolvency courts of justice, their material and territorial competence and the procedure rules. Next chapters are dedicated to the insolvency judge, receiver and liquidator and analyze the following issues: their appointment, their powers, their auxiliary officials and their ceasing of the powers. Some regards on the British law and French law are also included. The next chapter is dedicated to the participants to the insolvency procedure: the creditors general assembly, creditors committee and special administrator, followed by conclusions and recommendations.

  7. The Influence of 8-Weeks of Whey Protein and Leucine Supplementation on Physical and Cognitive Performance

    Science.gov (United States)

    2009-03-01

    extension resistance training than did a carbohydrate placebo (22%). Protein and branched chain amino acids ( BCAA ) supplementation may also improve... BCAAs scored better on both mood levels and 2 Approved for public release; distribution unlimited, Public Affairs Case File No. 09-189, 27 April 2009...supplemented subjects with whey and casein (WC), whey and BCAAs (WBC), or placebo (P) over 10 weeks of resistance training (RT). They observed a significant

  8. Separating the mink dam from the litter at 7 or 8 weeks after delivery

    DEFF Research Database (Denmark)

    Malmkvist, Jens; Palme, Rupert; Larsen, Torben

    2015-01-01

    around the time of separation. Therefore, we investigated the effects of separating the dam from the litter, using brown first-parity dams (N=374) randomly assigned within each date of delivery to two treatment groups: The dam was taken away from the litter either at day 49 ±1 (7w, N=185) or at day 56 ±1......The optimal timing of separating the mink dam from the litter is suggested to be a balance between the partly conflicting needs of the mother and the kits. Early removal of the dam or partial removal of the litter may protect the dam against exhaustion. Little is known about the maternal motivation...... groups had an equal litter size at the time of separation (age 7w: 5.5 ±0.17; 8w: 5.5 ±0.17 kits; range 1-11; P=0.76). Likewise, there was no significant difference in dam body weight (7w: 1420 ±15.0 g, 8w: 1404 ±14.7 g; range 930-1680 g, P=0.43). However, the litter size negatively influenced both...

  9. The benefits of yoga for rheumatoid arthritis: results of a preliminary, structured 8-week program.

    Science.gov (United States)

    Badsha, Humeira; Chhabra, Vishwas; Leibman, Cathy; Mofti, Ayman; Kong, Kok Ooi

    2009-10-01

    The aim of this study was to measure the effects of a bi-weekly Raj yoga program on rheumatoid arthritis (RA) disease activity. Subjects were recruited from among RA patients in Dubai, United Arab Emirates by email invitations of the RA database. Demographic data, disease activity indices, health assessment questionnaire (HAQ), and quality of life (QOL) by SF-36 were documented at enrollment and after completion of 12 sessions of Raj yoga. A total of 47 patients were enrolled: 26 yoga and 21 controls. Baseline demographics were similar in both groups. Patients who underwent yoga had statistically significant improvements in DAS28 and HAQ, but not QOL. Our pilot study of 12 sessions of yoga for RA was able to demonstrate statistically significant improvements in RA disease parameters. We believe that a longer duration of treatment could result in more significant improvements.

  10. A multicentre weight loss study using a low-calorie diet over 8 weeks

    DEFF Research Database (Denmark)

    Papadaki, Angeliki; Linardakis, Manolis; Plada, Maria

    2013-01-01

    The efficacy of low-calorie diets (LCDs) has not been investigated in large-scale studies or among people from different regions, who are perhaps unaccustomed to such methods of losing weight. The aim of the present study was to investigate changes in obesity measures among overweight/obese adults...

  11. An 8-Week Neuromuscular Exercise Program for Patients With Mild to Moderate Knee Osteoarthritis

    DEFF Research Database (Denmark)

    Clausen, Brian; Holsgaard-Larsen, Anders; Roos, Ewa M

    2017-01-01

    OBJECTIVE:   To describe the feasibility of a neuromuscular exercise (NEMEX) program in patients with mild to moderate knee osteoarthritis (KOA). BACKGROUND:   Neuromuscular exercise has been increasingly used in patients with osteoarthritis to achieve sensorimotor control and improved daily func...

  12. Participation in cancer rehabilitation and unmet needs

    DEFF Research Database (Denmark)

    Holm, Lise Vilstrup; Hansen, Dorte Gilså; Johansen, Christoffer

    2012-01-01

    PURPOSE: To investigate associations between cancer survivors' sex, age, and diagnosis in relation to their (1) need for rehabilitation, (2) participation in rehabilitation activities, and (3) unmet needs for rehabilitation in a 14-month period following date of diagnosis. METHODS: A population...... sex, age, and diagnosis, and the outcome variables for rehabilitation. RESULTS: A total of 3,439 patients participated, yielding an overall response rate of 70%. One third of the cancer patients reported a need for physical rehabilitation and one third for psychological rehabilitation. Half...... of the patients participated in at least one activity. Unmet needs were most often reported in psychological, sexual, and financial areas. Women expressed more needs, participated more often in rehabilitation activities, and had, to a higher extent, their emotional needs fulfilled. Breast cancer patients...

  13. Participation for Development

    DEFF Research Database (Denmark)

    Dittrich, Yvonne; De La Harpe, Retha; Korpela, Mikko

    2014-01-01

    Information and Communication Technology (ICT) is more and more promoted as a driver and facilitator of economic growth and development in low and middle income countries. ICT for Development (ICT4D) though has mixed successes. Sustainability of solutions and usability respectively usefulness...... for the intended beneficiaries have been reported as causes. Participatory approaches to development have been proposed to address these causes. Participatory Design (PD) seems like a perfect fit. However, at the Participatory Design Conferences, research that addresses PD in low and middle income countries...... is rare. The workshop aims at bringing together the PD researchers working with under-privileged communities and attracting researchers from the ICT4D communities to the PD conference. The goal is to share experiences and start a discussion on how participation, ICT and development might relate....

  14. (Radio)active participation

    CERN Document Server

    Anaïs Schaeffer

    2014-01-01

    This year, for the first time, CERN hosted the Rencontres internationales lycéennes de la radioprotection: a three-day event in which some 200 students from 16 schools in France and elsewhere came together to discuss the topic of radiation protection and to deepen their understanding of the field.   Participants of the Rencontres internationales lycéennes de la radioprotection 2014. Each year since 2008, the Centre d’étude sur l’évaluation de la protection dans le domaine nucléaire français (CEPN, the French centre for studies of the evaluation of nuclear protection) and the Institut de radioprotection et de sûreté nucléaire français (IRSN, the French institute for radiation protection and nuclear safety), in partnership with various other bodies*, have been organising radiation protection workshops. Aimed at students between the ages of 15 and 18 from France and beyo...

  15. Participating in patient education

    DEFF Research Database (Denmark)

    Kristiansen, Tine Mechlenborg; Antoft, Rasmus

    2015-01-01

    The paper builds on previous ethnographic research in Denmark focusing on the significance of participating in a locally developed patient education programme for everyday life (Kristiansen et.al. 2015). It presents a secondary analysis. Group based patient education can be understood as a health...... promoting initiative. It is set up to regularize and help people manage the status passage from being a normal person to becoming a person living with chronic illness and to support them in accepting and learning to live with this identity transition. The theory of status passage and the concept of turning...... point is applied in order to illustrate two central status passages taking place at the locally developed patient education programme: 1) The status passage from novice to an experienced person with chronic illness, and 2) The transformation from adolescence to adulthood living with a chronic illness...

  16. Community-Academic Partnership Participation.

    Science.gov (United States)

    Meza, Rosemary; Drahota, Amy; Spurgeon, Emily

    2016-10-01

    Community-academic partnerships (CAPs) improve the research process, outcomes, and yield benefits for the community and researchers. This exploratory study examined factors important in community stakeholders' decision to participate in CAPs. Autism spectrum disorder (ASD) community stakeholders, previously contacted to participate in a CAP (n = 18), completed the 15-item Decision to Participate Questionnaire (DPQ). The DPQ assessed reasons for participating or declining participation in the ASD CAP. CAP participants rated networking with other providers, fit of collaboration with agency philosophy, and opportunity for future training/consultations as factors more important in their decision to participate in the ASD CAP than nonparticipants. Nonparticipants reported the number of requests to participate in research as more important in their decision to decline participation than participants. Findings reveal important factors in community stakeholders' decision to participate in CAPs that may provide guidance on increasing community engagement in CAPs and help close the science-to-service gap.

  17. 辛亥革命时期女性报刊和女子参政运动%ON FEMALE NEWSPAPERS AND JOURNALS AND THE MOVEMENT OF WOMEN'S PARTICIPATION IN THE POLITICS DURING THE PERIOD OF THE REVOLUTION OF 1911

    Institute of Scientific and Technical Information of China (English)

    简姿亚

    2011-01-01

    Along with the victory of the Revolution of 1911, there came a first upsurge of women's seeking political participating rights movement which launched by intelligent women and led by women themselves. Female newspapers and journals launched during the year of 1911 to 1913 are characterized by advocating women's political participation right. Among them, Female Newspaper of Shenzhou, Women's Vernacular Journal and International Women's Participation in the Politics Magazine are three of the most influential female journals in advocating women's participation in the politics. As a means of public opinion, female journals had undoubtedly given impetus to the movement of women seeking political participation rights in real life and pushed forward the trend of thought of women's participation in the politics. Nevertheless, confined to the era, female journals had played a significant but limited role in advocating women's political participation right.%随着辛亥革命的胜利,知识女性们第一次掀起了由女性自己领导的、争取女子参政权运动的高潮。而1911年至1913年创办的女性报刊.其主要特色便是鼓吹女子参政。其中,《神州女报》、《女子白话报》和《万国女子参政会旬报》成为鼓吹女子参政的最有力的三大女性刊物。作为舆论鼓吹工具,女性报刊无疑推动着现实生活中女子参政运动和参政思潮的向前发展,不过,因时代的局限性,女性报刊对于女子参政的宣传鼓动作用有效,但也有限。

  18. Periodicity of chaotic solutions

    CERN Document Server

    Berezowski, Marek

    2016-01-01

    The scope of the paper is the analysis of the impact of flow reversal on the dynamics of cascades of reactors. Periodic and chaotic oscillations occur in the analyzed system. There is a dependence between the oscillation period of the state variable of the system without flow reversal and the recurrence period of windows of chaos in the steady-state diagram of the system with flow reversal.

  19. Bott periodicity of inclusions

    CERN Document Server

    Mare, Augustin-Liviu

    2011-01-01

    When looking at Bott's original proof of his periodicity theorem for the stable homotopy groups of the orthogonal and unitary groups, one sees in the background a differential geometric periodicity phenomenon. We show that this geometric phenomenon extends to the standard inclusion of the orthogonal group into the unitary group. This explains the periodicity of the group homomorphisms between stable homotopy groups which are induced by the inclusion map. Standard inclusions between other classical Riemannian symmetric spaces are also discussed.

  20. Painful menstrual periods

    Science.gov (United States)

    Menstruation - painful; Dysmenorrhea; Periods - painful; Cramps - menstrual; Menstrual cramps ... related activities for a few days during each menstrual cycle. Painful menstruation is the leading cause of ...

  1. Hypokalemic periodic paralysis

    National Research Council Canada - National Science Library

    Abbas, Haider; Kothari, Nikhil; Bogra, Jaishri

    2012-01-01

    Hypokalemic periodic paralysis is a rare genetic disorder characterized by recurrent attacks of skeletal muscle weakness with associated hypokalemia which is precipitated by stress, cold, carbohydrate...

  2. Women’s Studies Enters New Period

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    Moving Into a Decision-Making Period Redefining gender relationships in terms of scientific research, and scientifically determining the influence women have on social decision-making forces is a new subject in women’s studies since the 1980s in China. Channels enabling women to participate in decision-making processes have grown significantly. Women’s studies organizations and specialists in the field directly participate in government decision-making processes. The promulgation and

  3. Peculiarities of perfection of training process of the qualified bodybuilder in the competitive period

    Directory of Open Access Journals (Sweden)

    Dzhym V.Yu.

    2015-02-01

    Full Text Available Purpose: study methods of improving the training process of skilled bodybuilders in the competitive period. Material : The study involved 18 athletes aged 18-25 years old. The experiment was conducted for 8 weeks. Used two variants of training techniques: large percentage weights; with smooth dynamics with emphasis on static load muscles. Efficacy was evaluated using the preparation method of expert evaluations. The method involved the use of information on the implementation of directives coach dynamics of power and endurance performance, subjective indicators (health, mood, desire to train. Results : comparative characteristic of the most commonly used methods of training process in bodybuilding. Developed and justified best practices, depending on the initial form of the athlete at the beginning of the competition period of training. Shows the dependence of changes in body weight of the athlete training. Conclusions : the proposed best practices, depending on the microcycle training in the competitive period (precompetitive and competitive mesocycles.

  4. Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis.

    Science.gov (United States)

    Sanyal, Debmalya; Bhattacharjee, Shakya

    2013-04-01

    Silent thyroiditis is a rare cause of thyrotoxic periodic paralysis. The objective was to present a case of silent thyroiditis presenting as periodic paralysis. A 23-year-old man presented with recurrent acute flaccid predominantly proximal weakness of all four limbs. He had a similar episode 3 weeks back. On examination he was found to have hypokalemia secondary to thyrotoxicosis. Clinically there were no features of thyrotoxicosis or thyroiditis. He was initially treated with intravenous and later oral potassium supplementation and propranolol. At 8 weeks of follow-up his thyroid profile became normal and his propranolol was stopped. He had no further recurrence of paralysis. He was diagnosed as a case silent thyroiditis presenting as thyrotoxic periodic paralysis. In cases of recurrent or acute flaccid muscle paralysis, it is important to suspect thyrotoxicosis, even if asymptomatic. Definitive treatment of thyrotoxicosis prevents recurrence.

  5. Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis

    Directory of Open Access Journals (Sweden)

    Debmalya Sanyal

    2013-01-01

    Full Text Available Silent thyroiditis is a rare cause of thyrotoxic periodic paralysis. The objective was to present a case of silent thyroiditis presenting as periodic paralysis. A 23-year-old man presented with recurrent acute flaccid predominantly proximal weakness of all four limbs. He had a similar episode 3 weeks back. On examination he was found to have hypokalemia secondary to thyrotoxicosis. Clinically there were no features of thyrotoxicosis or thyroiditis. He was initially treated with intravenous and later oral potassium supplementation and propranolol. At 8 weeks of follow-up his thyroid profile became normal and his propranolol was stopped. He had no further recurrence of paralysis. He was diagnosed as a case silent thyroiditis presenting as thyrotoxic periodic paralysis. In cases of recurrent or acute flaccid muscle paralysis, it is important to suspect thyrotoxicosis, even if asymptomatic. Definitive treatment of thyrotoxicosis prevents recurrence.

  6. Second Period Access Report

    DEFF Research Database (Denmark)

    Maisondieu, Christophe; Giebhardt, Jochen; Tetu, Amelie

    The work described in this publication has received support from the European Community - Research Infrastructure Action under the FP7 “Capacities” Specific Programme through grant agreement number 262552, MaRINET. Project Periodic Report. 2nd Period: October 2012 – March 2014 inclusive....

  7. The Living Periodic Table

    Science.gov (United States)

    Nahlik, Mary Schrodt

    2005-01-01

    To help make the abstract world of chemistry more concrete eighth-grade students, the author has them create a living periodic table that can be displayed in the classroom or hallway. This display includes information about the elements arranged in the traditional periodic table format, but also includes visual real-world representations of the…

  8. Latent Period of Relaxation.

    Science.gov (United States)

    Kobayashi, M; Irisawa, H

    1961-10-27

    The latent period of relaxation of molluscan myocardium due to anodal current is much longer than that of contraction. Although the rate and the grade of relaxation are intimately related to both the stimulus condition and the muscle tension, the latent period of relaxation remains constant, except when the temperature of the bathing fluid is changed.

  9. On some periodicity effects

    DEFF Research Database (Denmark)

    Sorokin, Sergey V.

    2015-01-01

    The talk is concerned with the modelling of wave propagation in and vibration of periodic elastic structures. Although analysis of wave-guide properties of infinite periodic structures is a well establish research subject, some issues have not yet been fully addressed in the literature. The aim o...

  10. The Living Periodic Table

    Science.gov (United States)

    Nahlik, Mary Schrodt

    2005-01-01

    To help make the abstract world of chemistry more concrete eighth-grade students, the author has them create a living periodic table that can be displayed in the classroom or hallway. This display includes information about the elements arranged in the traditional periodic table format, but also includes visual real-world representations of the…

  11. Periodic Time Series Models

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); R. Paap (Richard)

    2004-01-01

    textabstractThis book considers periodic time series models for seasonal data, characterized by parameters that differ across the seasons, and focuses on their usefulness for out-of-sample forecasting. Providing an up-to-date survey of the recent developments in periodic time series, the book

  12. Periods and Nori motives

    CERN Document Server

    Huber, Annette

    2017-01-01

    This book casts the theory of periods of algebraic varieties in the natural setting of Madhav Nori’s abelian category of mixed motives. It develops Nori’s approach to mixed motives from scratch, thereby filling an important gap in the literature, and then explains the connection of mixed motives to periods, including a detailed account of the theory of period numbers in the sense of Kontsevich-Zagier and their structural properties. Period numbers are central to number theory and algebraic geometry, and also play an important role in other fields such as mathematical physics. There are long-standing conjectures about their transcendence properties, best understood in the language of cohomology of algebraic varieties or, more generally, motives. Readers of this book will discover that Nori’s unconditional construction of an abelian category of motives (over fields embeddable into the complex numbers) is particularly well suited for this purpose. Notably, Kontsevich's formal period algebra represents a to...

  13. The People with Arthritis Can Exercise (PACE Program: A Qualitative Evaluation of Participant Satisfaction

    Directory of Open Access Journals (Sweden)

    Leigh F. Callahan, PhD

    2005-07-01

    Full Text Available Introduction Developed by the Arthritis Foundation, People with Arthritis Can Exercise is a community-based exercise program for individuals with arthritis. This qualitative study was designed to assess participant satisfaction with the program and examine motivators and barriers to attending program classes. Methods We conducted an 8-week randomized controlled trial of People with Arthritis Can Exercise among 347 participants residing in 18 urban and rural communities across North Carolina. Semistructured telephone interviews were conducted with 51 of the participants. Participants were asked about their overall satisfaction with the program. Motivating factors and barriers to attending the classes, including content, instructor, location, and schedule, were examined. Results Of the 51 participants interviewed, 96% were female, with an average age in years of 67 (range, 32–90 years. Participants reported deriving considerable social support from exercising in a group with others who have arthritis. They identified two main factors that motivated them to continue participating in the exercise class: ability to work at their own pace during the class and confidence that they could do different kinds of exercise safely. Participants also reported that the instructor played a vital role in sustaining their motivation to exercise. Among the participants, noncompleters of the program reported arthritis-related illness or insufficient physical challenge as key barriers to class participation. Conclusion This study suggests that a group exercise program for older adults with arthritis promotes a sense of social support and increases self-efficacy for exercise by allowing participants to work at their own pace.

  14. Dynamic Stock Market Participation of Households with Heterogeneous Participation Costs

    DEFF Research Database (Denmark)

    Khorunzhina, Natalia

    This paper develops and estimates a dynamic model of stock market participation, where consumers’ decisions regarding stock market participation are influenced by participation costs. The practical significance of the participation costs is considered as being a channel through which financial...... education programs can affect consumers’ investment decisions. Using household data from the Panel Study of Income Dynamics, I estimate the magnitude of the participation cost, allowing for individual heterogeneity in it. The results show the average stock market participation cost is about 5% of labor...... income; however, it varies substantially over consumers’ life. The model successfully predicts the level of the observed participation rate and the increasing pattern of stock market participation over the consumers’ life cycle....

  15. Effects of Short-Term Free-Weight and Semiblock Periodization Resistance Training on Metabolic Syndrome.

    Science.gov (United States)

    South, Mark A; Layne, Andrew S; Stuart, Charles A; Triplett, N Travis; Ramsey, Michael; Howell, Mary E; Sands, William A; Mizuguchi, Satoshi; Hornsby, W Guy; Kavanaugh, Ashley A; Stone, Michael H

    2016-10-01

    South, MA, Layne, AS, Stuart, CA, Triplett, NT, Ramsey, MW, Howell, ME, Sands, WA, Mizuguchi, S, Hornsby, WG, Kavanaugh, AA, and Stone, MH. Effects of short-term free-weight and semiblock periodization resistance training on metabolic syndrome. J Strength Cond Res 30(10): 2682-2696, 2016-The effects of short-term resistance training on performance and health variables associated with prolonged sedentary lifestyle and metabolic syndrome (MS) were investigated. Resistance training may alter a number of health-related, physiological, and performance variables. As a result, resistance training can be used as a valuable tool in ameliorating the effects of a sedentary lifestyle including those associated with MS. Nineteen previously sedentary subjects (10 with MS and 9 with nonmetabolic syndrome [NMS]) underwent 8 weeks of supervised resistance training. Maximum strength was measured using an isometric midthigh pull and resulting force-time curve. Vertical jump height (JH) and power were measured using a force plate. The muscle cross-sectional area (CSA) and type were examined using muscle biopsy and standard analysis techniques. Aerobic power was measured on a cycle ergometer using a ParvoMedics 2400 Metabolic system. Endurance was measured as time to exhaustion on a cycle ergometer. After training, maximum isometric strength, JH, jump power, and V[Combining Dot Above]O2peak increased by approximately 10% (or more) in both the metabolic and NMS groups (both male and female subjects). Over 8 weeks of training, body mass did not change statistically, but percent body fat decreased in subjects with the MS and in women, and lean body mass increased in all groups (p ≤ 0.05). Few alterations were noted in the fiber type. Men had larger CSAs compared those of with women, and there was a fiber-specific trend toward hypertrophy over time. In summary, 8 weeks of semiblock free-weight resistance training improved several performance variables and some cardiovascular factors

  16. Ethical Challenges: To Participate or Not to Participate?

    Science.gov (United States)

    Cooksy, Leslie J.

    2006-01-01

    This issue's scenario, To Participate or Not to Participate, describes an evaluator's shift in method from nonparticipant to participant observation. Although evaluation theorists differ on the extent to which methods decisions are ethical decisions (Morris, 1998), neither of the two commentators considers the methodological decision problematic;…

  17. Mean-periodic functions

    Directory of Open Access Journals (Sweden)

    Carlos A. Berenstein

    1980-01-01

    Full Text Available We show that any mean-periodic function f can be represented in terms of exponential-polynomial solutions of the same convolution equation f satisfies, i.e., u∗f=0(μ∈E′(ℝn. This extends to n-variables the work of L. Schwartz on mean-periodicity and also extends L. Ehrenpreis' work on partial differential equations with constant coefficients to arbitrary convolutors. We also answer a number of open questions about mean-periodic functions of one variable. The basic ingredient is our work on interpolation by entire functions in one and several complex variables.

  18. The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period

    DEFF Research Database (Denmark)

    Sloth, Birgitte; Due, Anette Pia; Larsen, Thomas Meinert

    2008-01-01

    We aimed to test the effects of three different weight maintenance diets on appetite, glucose and fat metabolism following an initial low-energy diet (LED) induced body weight loss. Following an 8-week LED and a 2-3-week refeeding period, 131 subjects were randomized to three diets for 6 months: ...... and 2-3-week refeeding period, suggest that strategies for physiological appetite control following a LED period are needed, in order to prevent weight regain.......We aimed to test the effects of three different weight maintenance diets on appetite, glucose and fat metabolism following an initial low-energy diet (LED) induced body weight loss. Following an 8-week LED and a 2-3-week refeeding period, 131 subjects were randomized to three diets for 6 months....... No difference in body weight, energy intake or appetite ratings were observed between diets. Both the LF and MUFA diets compared to CTR diet reduced postprandial glycaemia and insulinaemia and lowered fasting insulin from month 0 to month 6. Following the 8-week LED period lower levels of the appetite...

  19. Mobility devices to promote activity and participation

    DEFF Research Database (Denmark)

    Salminen, Anna-Liisa; Brandt, Ase; Samuelsson, Kersti A M

    2009-01-01

    OBJECTIVE: To determine the effectiveness of mobility device interventions in terms of activity and participation for people with mobility limitations. DESIGN: Systematic review. Search of 7 databases during the period 1996 to 2008. METHODS: Controlled studies and non-controlled follow-up studies...... were included if they covered both baseline and follow-up data and focused on activity and participation. Study participants had to be aged over 18 years with mobility limitations. Mobility device interventions encompassed crutches, walking frames, rollators, manual wheelchairs and powered wheelchairs......, and 3 follow-up studies that included before and after data. Two studies dealt with the effects of powered wheelchair interventions and the other studies with various other types of mobility device. Two studies were of high, internal and external methodological quality. Interventions were found...

  20. Setting the Periodic Table.

    Science.gov (United States)

    Saturnelli, Annette

    1985-01-01

    Examines problems resulting from different forms of the periodic table, indicating that New York State schools use a form reflecting the International Union of Pure and Applied Chemistry's 1984 recommendations. Other formats used and reasons for standardization are discussed. (DH)

  1. The Periodic Table CD.

    Science.gov (United States)

    Banks, Alton J.; Holmes, Jon L.

    1995-01-01

    Describes the characteristics of the digitized version of The Periodic Table Videodisc. Provides details about the organization of information and access to the data via Macintosh and Windows computers. (DDR)

  2. Familial Periodic Paralyses

    Science.gov (United States)

    ... and less severe than the hypokalemic form. Muscle spasms are common. × Definition Familial periodic paralyses are a ... and less severe than the hypokalemic form. Muscle spasms are common. View Full Definition Treatment Treatment of ...

  3. Extremal periodic wave profiles

    Directory of Open Access Journals (Sweden)

    E. van Groesen

    2007-01-01

    Full Text Available As a contribution to deterministic investigations into extreme fluid surface waves, in this paper wave profiles of prescribed period that have maximal crest height will be investigated. As constraints the values of the momentum and energy integrals are used in a simplified description with the KdV model. The result is that at the boundary of the feasible region in the momentum-energy plane, the only possible profiles are the well known cnoidal wave profiles. Inside the feasible region the extremal profiles of maximal crest height are "cornered" cnoidal profiles: cnoidal profiles of larger period, cut-off and periodically continued with the prescribed period so that at the maximal crest height a corner results.

  4. On semi-periods

    CERN Document Server

    Avram, A C; Jancic, D; Uni, H; Uni, Humboldt

    1995-01-01

    The periods of the three-form on a Calabi-Yau manifold are found as solutions of the Picard-Fuchs equations; however, the toric varietal method leads to a generalized hypergeometric system of equations which has more solutions than just the periods. This same extended set of equations can be derived from symmetry considerations. Semi-periods are solutions of this extended system. They are obtained by integration of the three-form over chains; these chains can be used to construct cycles which, when integrated over, give periods. In simple examples we are able to obtain the complete set of solutions for the extended system. We also conjecture that a certain modification of the method will generate the full space of solutions in general.

  5. Setting the Periodic Table.

    Science.gov (United States)

    Saturnelli, Annette

    1985-01-01

    Examines problems resulting from different forms of the periodic table, indicating that New York State schools use a form reflecting the International Union of Pure and Applied Chemistry's 1984 recommendations. Other formats used and reasons for standardization are discussed. (DH)

  6. The Periodic Table CD.

    Science.gov (United States)

    Banks, Alton J.; Holmes, Jon L.

    1995-01-01

    Describes the characteristics of the digitized version of The Periodic Table Videodisc. Provides details about the organization of information and access to the data via Macintosh and Windows computers. (DDR)

  7. Optimal periodic control

    CERN Document Server

    Colonius, Fritz

    1988-01-01

    This research monograph deals with optimal periodic control problems for systems governed by ordinary and functional differential equations of retarded type. Particular attention is given to the problem of local properness, i.e. whether system performance can be improved by introducing periodic motions. Using either Ekeland's Variational Principle or optimization theory in Banach spaces, necessary optimality conditions are proved. In particular, complete proofs of second-order conditions are included and the result is used for various versions of the optimal periodic control problem. Furthermore a scenario for local properness (related to Hopf bifurcation) is drawn up, giving hints as to where to look for optimal periodic solutions. The book provides mathematically rigorous proofs for results which are potentially of importance in chemical engineering and aerospace engineering.

  8. Hyperkalemic periodic paralysis

    Science.gov (United States)

    ... Rott K, Rudel R, Lehmann-Horn F. Muscle channelopathies: myotonias and periodic paralyses. In: Darras BT, Jones ... Elsevier; 2015:chap 38. Kerchner GA, Ptacek LJ. Channelopathies: episodic and electrical disorders of nervous system. In: ...

  9. Hypokalemic periodic paralysis

    Science.gov (United States)

    ... Rott K, Rudel R, Lehmann-Horn F. Muscle channelopathies: myotor and periodic paralyses. In: Darras BT, Jones ... Elsevier; 2015:chap 38. Kerchner GA, Ptacek LJ. Channelopathies. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy ...

  10. Historically defined autobiographical periods

    DEFF Research Database (Denmark)

    Brown, Norman R.; Hansen, Tia G. B.; Lee, Peter J.;

    2012-01-01

    The chapter reviews a research programme that has demonstrated the existence of historically defined autobiographical periods and identified the conditions that bring them about. Data from four samples of World War II-generation adults show that historically defined autobiographical periods endure...... over time and theoretical implications are discussed, notably by introducing a new approach to autobiographical memory, Transition Theory, which assumes that autobiographical memory is organized by transitional events that can be selfinitiated or externally imposed - historically defined...

  11. Social Mobility and Social Participation

    Science.gov (United States)

    Sewell, William H.

    1978-01-01

    Examines data related to social mobility and social participation of Americans. Topics include educational and occupational mobility; voting; volunteer work; charitable giving; community participation; views on religion; and anomie. For journal availability, see SO 506 144. (Author/DB)

  12. Social Mobility and Social Participation

    Science.gov (United States)

    Sewell, William H.

    1978-01-01

    Examines data related to social mobility and social participation of Americans. Topics include educational and occupational mobility; voting; volunteer work; charitable giving; community participation; views on religion; and anomie. For journal availability, see SO 506 144. (Author/DB)

  13. 7 CFR 247.16 - Certification period.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.16 Certification period. (a.... However, pregnant women may be certified to participate for the duration of their pregnancy and for up...

  14. Periodic Ising Correlations

    CERN Document Server

    Hystad, Grethe

    2010-01-01

    In this paper, we first rework B. Kaufman's 1949 paper, "Crystal Statistics. II. Partition Function Evaluated by Spinor Analysis", by using representation theory. Our approach leads to a simpler and more direct way of deriving the spectrum of the transfer matrix for the finite periodic Ising model. We then determine formulas for the spin correlation functions that depend on the matrix elements of the induced rotation associated with the spin operator in a basis of eigenvectors for the transfer matrix. The representation of the spin matrix elements is obtained by considering the spin operator as an intertwining map. We exhibit the "new" elements V+ and V- in the Bugrij-Lisovyy formula as part of a holomorphic factorization of the periodic and anti-periodic summability kernels on the spectral curve associated with the induced rotation for the transfer matrix.

  15. Thyrotoxic periodic paralysis

    Directory of Open Access Journals (Sweden)

    Rojith Karandode Balakrishnan

    2011-01-01

    Full Text Available This article aims at highlighting the importance of suspecting thyrotoxicosis in cases of recurrent periodic flaccid paralysis; especially in Asian men to facilitate early diagnosis of the former condition. A case report of a 28 year old male patient with recurrent periodic flaccid paralysis has been presented. Hypokalemia secondary to thyrotoxicosis was diagnosed as the cause of the paralysis. The patient was given oral potassium intervention over 24 hours. The patient showed complete recovery after the medical intervention and was discharged after 24 hours with no residual paralysis. Thyrotoxic periodic paralysis (TPP is a complication of thyrotoxicosis, more common amongst males in Asia. It presents as acute flaccid paralysis in a case of hyperthyroidism with associated hypokalemia. The features of thyrotoxicosis may be subtle or absent. Thus, in cases of recurrent or acute flaccid muscle paralysis, it is important to consider thyrotoxicosis as one of the possible causes, and take measures accordingly.

  16. Hyperthyroid hypokalemic periodic paralysis.

    Science.gov (United States)

    Neki, N S

    2016-01-01

    Hyperthyroid periodic paralysis (HPP) is a rare life threatening complication of hyperthyroidism commonly occurring in young Asian males but sporadically found in other races. It is characterised by hypokalemia and acute onset paraparesis with prevalence of one in one hundred thousand (1 in 100000). The symptoms resolve promptly with potassium supplementation. Nonselective beta blockers like propranol can also be used to ameliorate and prevent subsequent paralytic attack. We report a case of 22 year old male presenting with hyperthyroid periodic paralysis (HPP) having very low serum potassium level.

  17. [Discussion paper on participation and participative methods in gerontology].

    Science.gov (United States)

    Aner, Kirsten

    2016-02-01

    The concept of "participation" and the demand for the use of "participative methods" in human, healthcare, nursing and gerontological research as well as the corresponding fields of practice are in great demand; however, the targets and organization of "participation" are not always sufficiently explicated. The working group on critical gerontology of the German Society of Gerontology and Geriatrics uses this phenomenon as an opportunity for positioning and develops a catalogue of criteria for reflection and assessment of participation of elderly people in science and practice, which can also be considered a stimulus for further discussions.

  18. Hereditary periodic fever syndromes

    NARCIS (Netherlands)

    McDermott, MF; Frenkel, J

    Hereditary periodic fever syndromes are defined by recurrent attacks of generalised inflammation for which no infectious or auto-immune cause can be identified. For most of these disorders, the molecular basis has recently been elucidated. This has opened the prospect of novel therapeutic

  19. Periodic Table of Students.

    Science.gov (United States)

    Johnson, Mike

    1998-01-01

    Presents an exercise in which an eighth-grade science teacher decorated the classroom with a periodic table of students. Student photographs were arranged according to similarities into vertical columns. Students were each assigned an atomic number according to their placement in the table. The table is then used to teach students about…

  20. A Modern Periodic Table.

    Science.gov (United States)

    Herrenden-Harker, B. D.

    1997-01-01

    Presents a modern Periodic Table based on the electron distribution in the outermost shell and the order of filling of the sublevels within the shells. Enables a student to read off directly the electronic configuration of the element and the order in which filling occurs. (JRH)

  1. Oscillations following periodic reinforcement.

    Science.gov (United States)

    Monteiro, Tiago; Machado, Armando

    2009-06-01

    Three experiments examined behavior in extinction following periodic reinforcement. During the first phase of Experiment 1, four groups of pigeons were exposed to fixed interval (FI 16s or FI 48s) or variable interval (VI 16s or VI 48s) reinforcement schedules. Next, during the second phase, each session started with reinforcement trials and ended with an extinction segment. Experiment 2 was similar except that the extinction segment was considerably longer. Experiment 3 replaced the FI schedules with a peak procedure, with FI trials interspersed with non-food peak interval (PI) trials that were four times longer. One group of pigeons was exposed to FI 20s PI 80s trials, and another to FI 40s PI 160s trials. Results showed that, during the extinction segment, most pigeons trained with FI schedules, but not with VI schedules, displayed pause-peck oscillations with a period close to, but slightly greater than the FI parameter. These oscillations did not start immediately after the onset of extinction. Comparing the oscillations from Experiments 1 and 2 suggested that the alternation of reconditioning and re-extinction increases the reliability and earlier onset of the oscillations. In Experiment 3 the pigeons exhibited well-defined pause-peck cycles since the onset of extinction. These cycles had periods close to twice the value of the FI and lasted for long intervals of time. We discuss some hypotheses concerning the processes underlying behavioral oscillations following periodic reinforcement.

  2. Periodically poled silicon

    Science.gov (United States)

    Hon, Nick K.; Tsia, Kevin K.; Solli, Daniel R.; Khurgin, Jacob B.; Jalali, Bahram

    2010-02-01

    Bulk centrosymmetric silicon lacks second-order optical nonlinearity χ(2) - a foundational component of nonlinear optics. Here, we propose a new class of photonic device which enables χ(2) as well as quasi-phase matching based on periodic stress fields in silicon - periodically-poled silicon (PePSi). This concept adds the periodic poling capability to silicon photonics, and allows the excellent crystal quality and advanced manufacturing capabilities of silicon to be harnessed for devices based on χ(2)) effects. The concept can also be simply achieved by having periodic arrangement of stressed thin films along a silicon waveguide. As an example of the utility, we present simulations showing that mid-wave infrared radiation can be efficiently generated through difference frequency generation from near-infrared with a conversion efficiency of 50% based on χ(2) values measurements for strained silicon reported in the literature [Jacobson et al. Nature 441, 199 (2006)]. The use of PePSi for frequency conversion can also be extended to terahertz generation. With integrated piezoelectric material, dynamically control of χ(2)nonlinearity in PePSi waveguide may also be achieved. The successful realization of PePSi based devices depends on the strength of the stress induced χ(2) in silicon. Presently, there exists a significant discrepancy in the literature between the theoretical and experimentally measured values. We present a simple theoretical model that produces result consistent with prior theoretical works and use this model to identify possible reasons for this discrepancy.

  3. Treatment for periodic paralysis

    NARCIS (Netherlands)

    Sansone, [No Value; Meola, G.; Links, T. P.; Panzeri, M.; Rose, M. R.

    2008-01-01

    Background Primary periodic paralyses are rare inherited muscle diseases characterised by episodes of flaccid weakness affecting one or more limbs, lasting several hours to several days, caused by mutations in skeletal muscle channel genes. Objectives The objective of this review was to systematical

  4. A Modern Periodic Table.

    Science.gov (United States)

    Herrenden-Harker, B. D.

    1997-01-01

    Presents a modern Periodic Table based on the electron distribution in the outermost shell and the order of filling of the sublevels within the shells. Enables a student to read off directly the electronic configuration of the element and the order in which filling occurs. (JRH)

  5. Periodic Table of Students.

    Science.gov (United States)

    Johnson, Mike

    1998-01-01

    Presents an exercise in which an eighth-grade science teacher decorated the classroom with a periodic table of students. Student photographs were arranged according to similarities into vertical columns. Students were each assigned an atomic number according to their placement in the table. The table is then used to teach students about…

  6. Scheduling: Seven Period Day

    Science.gov (United States)

    Williamson, Ronald

    2010-01-01

    Driven by stable or declining financial resources many school districts are considering the costs and benefits of a seven-period day. While there is limited evidence that any particular scheduling model has a greater impact on student learning than any other, it is clear that the school schedule is a tool that can significantly impact teacher…

  7. Treatment for periodic paralysis

    NARCIS (Netherlands)

    Sansone, [No Value; Meola, G.; Links, T. P.; Panzeri, M.; Rose, M. R.

    2008-01-01

    Background Primary periodic paralyses are rare inherited muscle diseases characterised by episodes of flaccid weakness affecting one or more limbs, lasting several hours to several days, caused by mutations in skeletal muscle channel genes. Objectives The objective of this review was to systematical

  8. Chaotic period doubling

    NARCIS (Netherlands)

    Chandramouli, V. V. M. S.; Martens, M.; De Melo, W.; Tresser, C. P.

    2009-01-01

    The period doubling renormalization operator was introduced by Feigenbaum and by Coullet and Tresser in the 1970s to study the asymptotic small-scale geometry of the attractor of one-dimensional systems that are at the transition from simple to chaotic dynamics. This geometry turns out not to depend

  9. Researching participation in adult education

    DEFF Research Database (Denmark)

    Kondrup, Sissel

    labour. This has fostered an interest in examining why and how people engage in adult education, how participation and especially non-participation in adult education can be explained and how participation rates can be increased. In this paper I outline different traditions within research on recruitment......It is a widespread perception that the challenge of increasing participation in adult education and training has intensified due to the transformation from industrial to knowledge based societies and the transformation implies that it becomes pivotal to increase the supply of highly qualified...... to and participation in adult education and training focusing primarily on unskilled and low skilled workers. I present how the traditions contribute to the perception of what effects participation and argue that the existing traditions must be extended and a new framework must be applied in order to understand how...

  10. Researching participation in adult education

    DEFF Research Database (Denmark)

    Kondrup, Sissel

    It is a widespread perception that the challenge of increasing participation in adult education and training has intensified due to the transformation from industrial to knowledge based societies and the transformation implies that it becomes pivotal to increase the supply of highly qualified...... labour. This has fostered an interest in examining why and how people engage in adult education, how participation and especially non-participation in adult education can be explained and how participation rates can be increased. In this paper I outline different traditions within research on recruitment...... to and participation in adult education and training focusing primarily on unskilled and low skilled workers. I present how the traditions contribute to the perception of what effects participation and argue that the existing traditions must be extended and a new framework must be applied in order to understand how...

  11. Time, Attitude, and User Participation

    DEFF Research Database (Denmark)

    Pries-Heje, Lene

    2008-01-01

    , equivocation, resistance and rejection depending on three things: (1) the dynamic between user and consultants, (2) the dynamic between different user groups, and (3) the understanding of technical, organizational and socio-technical options. When relating the empirical findings to existing theory on user...... be that the perception of usefulness of the system in any given phase of the implementation is heavily dependent on preceding events—the process. A process model analysis identifies eight episodes and nine encounters in the case showing that the user’s attitude towards the ERP system changes between acceptance...... participation, it is argued that the changes could be explained as a slide from influential user participation toward pseudo participation and back to influential participation, and that user participation in the context of ERP implementations raises new issues regarding user participation. Thus further...

  12. Towards tailor-made participation

    DEFF Research Database (Denmark)

    Agger, Annika

    2012-01-01

    Public participation has become an important element of governance in many Western European countries. However, among scholars and practitioners there is a recognition that participatory governance processes tend to produce systematic exclusions. Knowledge about 'who' participates and 'how......' they participate can enhance our understanding of participatory processes. This paper presents some characterisations of citizens based on a review of the literature on participation. In addition, examples of how to tailor participation for different type of citizens are provided based on studies of urban...... regeneration programmes and local environmental initiatives in Denmark. The paper concludes that in order to broaden the inclusion of affected citizens, public authorities need to be tailor participation processes by applying distinct approaches to different types of citizens...

  13. Employee Participation in Europe: In search of the participative workplace

    NARCIS (Netherlands)

    Poutsma, E.; Hendrickx, J.; Huygen, F.

    2003-01-01

    This article presents an overview of participation schemes in European companies, It is based on a secondary analysis of data from the 1996 EPOC mail survey among managers of profit sector establishments in 10 EU countries. The article describes the diverse extent and nature of participative workpla

  14. Citizen participation in public accountability

    DEFF Research Database (Denmark)

    Damgaard, Bodil; Lewis, Jenny

    2014-01-01

    In this chapter we offer an analytical framework sensitive to the quality of citizen participation, which is measured in terms of transferred power from the governors to the citizens, and in terms of the degree to which citizens have access to accountability measures. We do this by combining...... Arnstein’s (1969) classic ladder of participation with a focus on citizen participation in regard to bureaucratic accountability, centered on efficiency and learning (cf. Bovens et al. 2008)....

  15. Political participation of registered nurses.

    Science.gov (United States)

    Vandenhouten, Christine L; Malakar, Crystalmichelle L; Kubsch, Sylvia; Block, Derryl E; Gallagher-Lepak, Susan

    2011-08-01

    Level of political participation and factors contributing to participation were measured among Midwest RNs (n = 468) via an online survey (Cronbach's α = .95). Respondents reported engaging in primarily "low cost" activities (e.g., voting, discussing politics, and contacting elected officials), with fewer reporting speaking at public gatherings, participating in demonstrations, and membership in nursing organizations. Psychological engagement was most predictive (p nursing organizations need to model and cultivate greater psychological engagement among students and nurses.

  16. Effect of booster shot and investigation of vaccination efficacy period against herpesviral haematopoietic necrosis (HVHN) in goldfish Carassius auratus.

    Science.gov (United States)

    Ito, Takafumi; Maeno, Yukio

    2015-01-30

    In this study, the efficacy period of an intraperitoneal vaccination and effect of a booster shot of vaccine against herpesviral haematopoietic necrosis (HVHN) in goldfish Carassius auratus were investigated. Cell culture supernatant of cyprinid herpesvirus 2 (CyHV-2), causative agent of HVHN, propagated in goldfish fin (GFF) cells was inactivated with formalin (0.1%, v/v) for 2 days at 4 °C. Three groups of the variety Ryukin were individually intraperitoneally injected with the vaccine and each group was separately maintained in replicate tanks. After 4 weeks (Vaccinated-4w-1 and 2) and 8 weeks (Vaccinated-8w-1 and 2) from the first vaccination, the fish were CyHV-2-challenged by the immersion route (10 TCID50 l(-1)). In addition, the other vaccinated group of fish were injected with a booster vaccine 4 weeks after the first vaccination as the Vaccinated-booster groups, then the fish of these groups were CyHV-2-challenged by the immersion route (10 TCID50 l(-1)) after 8 weeks from the first vaccination. The mean of the relative percentage survival (RPS) values of the Vaccinated-4w and 8w groups showed 42.5% and 57.6%, respectively. In addition, the mean RPS value of Vaccinated-booster groups showed 63.6%. Statistical analysis showed significantly higher survival rates in all the vaccinated groups than those of the respective negative control groups using Fisher's exact test. Moreover, the survival rates of vaccinated-booster groups were significantly higher (p=0.036) compared with the respective control groups by Student's t test. The present study shows the efficacy period of the vaccine is at least 8 weeks and a booster shot showed a tendency to enhance the protection against HVHN in goldfish.

  17. Development of students' interest in particle physics as effect of participating in a Masterclass

    Science.gov (United States)

    Gedigk, Kerstin; Pospiech, Gesche

    2016-05-01

    The International Hands On Particle Physics Masterclasses are enjoying increasing popularity worldwide every year. In Germany a national program was brought to live in 2010, which offers these appreciated events to whole classes or courses of high school students all over the year. These events were evaluated concerning the issues of students' interest in particle physics and their perception of the events. How several interest variables interact with each other and the perception of the events is answered by structural equation modelling (sect. 5.2). The results give information about the events' effects on the students' interest development in particle physics, show which event features are important ( e.g. the authenticity) and give information about practical approaches to improve the effects of the Masterclasses. Section 5.3 deals with a group of participants which have a high interest in particle physics 6-8 weeks after the participation. The number of these students is remarkable large, with 26% of all participants. The investigation of this group shows that the Masterclass participation has the same positive effect on both sexes and all levels of physics education.

  18. Thyrotoxic periodic paralysis

    Energy Technology Data Exchange (ETDEWEB)

    Ferreiro, J.E.; Arguelles, D.J.; Rams, H. Jr.

    1986-01-01

    A case of thyrotoxic periodic paralysis is reported in a Hispanic man with an unusual recurrence six weeks after radioactive iodine treatment. Thyrotoxic periodic paralysis has now been well characterized in the literature: it occurs primarily in Orientals with an overwhelming male preponderance and a higher association of specific HLA antigens. Clinical manifestations include onset after high carbohydrate ingestion or heavy exertion, with progressive symmetric weakness leading to flaccid paralysis of the extremities and other muscle groups, lasting several hours. If hypokalemia is present, potassium administration may help abort the attack. Although propranolol can be efficacious in preventing further episodes, the only definitive treatment is establishing a euthyroid state. The pathophysiology is still controversial, but reflects altered potassium and calcium dynamics as well as certain morphologic characteristics within the muscle unit itself.

  19. Cells anticipate periodic events

    Science.gov (United States)

    Nakagaki, Toshiyuki

    2009-03-01

    We show that an amoeboid organism can anticipate the timing of periodic events. The plasmodium of the true slime mold Physarum polycephalum moves rapidly under favourable conditions, but stops moving when transferred to less-favourable conditions. Plasmodia exposed to unfavourable conditions, presented in three consecutive pulses at constant intervals, reduced their locomotive speed in response to each episode. When subsequently subjected to favourable conditions, the plasmodia spontaneously reduced their locomotive speed at the time point when the next unfavourable episode would have occurred. This implied anticipation of impending environmental change. After this behaviour had been evoked several times, the locomotion of the plasmodia returned to normal; however, the anticipatory response could subsequently be induced by a single unfavourable pulse, implying recall of the memorized periodicity. We explored the mechanisms underlying these behaviours from a dynamical systems perspective. Our results hint at the cellular origins of primitive intelligence and imply that simple dynamics might be sufficient to explain its emergence.

  20. Periodic paralysis: understanding channelopathies.

    Science.gov (United States)

    Lehmann-Horn, Frank; Jurkat-Rott, Karin; Rüdel, Reinhardt

    2002-01-01

    Familial periodic paralyses are typical channelopathies (i.e., caused by functional disturbances of ion channel proteins). The episodes of flaccid muscle weakness observed in these disorders are due to underexcitability of sarcolemma leading to a silent electromyogram and the lack of action potentials even upon electrical stimulation. Interictally, ion channel malfunction is well compensated, so that special exogenous or endogenous triggers are required to produce symptoms in the patients. An especially obvious trigger is the level of serum potassium (K+), the ion responsible for resting membrane potential and degree of excitability. The clinical symptoms can be caused by mutations in genes coding for ion channels that mediate different functions for maintaining the resting potential or propagating the action potential, the basis of excitability. The phenotype is determined by the type of functional defect brought about by the mutations, rather than the channel effected, because the contrary phenotypes hyperkalemic periodic paralysis (HyperPP) and hypokalemic periodic paralysis (HypoPP) may be caused by point mutations in the same gene. Still, the common mechanism for inexcitability in all known episodic-weakness phenotypes is a long-lasting depolarization that inactivates sodium ion (Na+) channels, initiating the action potential.

  1. Educational Participation and Inmate Misconduct

    Science.gov (United States)

    Lahm, Karen F.

    2009-01-01

    The majority of extant literature on correctional education focuses on the relationship between program participation and recidivism while ignoring the possible relationship between educational program participation and inmate misconduct. The present study sought to fill in this gap in the literature by investigating the effect of several types of…

  2. Participant observation in risk problems

    NARCIS (Netherlands)

    Andriessen, H.; Kluin, M.H.A.; Van Gulijk, C.; Ale, B.J.M.

    2012-01-01

    Participant observation is a method to collect information through active participation in the social world that is under study, in this case two different risk-related working areas where confidentiality and secrecy are paramount. In reality there is a difference between what people do and say they

  3. Efficiency of participation in planning

    Directory of Open Access Journals (Sweden)

    Ghada Farouk Hassan

    2011-06-01

    A comparison between the two processes will take place in order to indentify the participation activities and their real efficiency. The comparison will be focused on the parameter of participation realized in each case in order to find gaps that have negative effects and needs to be filled.

  4. Who Benefits from Participative Management?

    Science.gov (United States)

    Benoliel, Pascale; Somech, Anit

    2010-01-01

    Purpose: This study seeks to explore the moderating role of teachers' personality traits from the Big Five typology on the relationship between participative management and teacher outcomes with respect to performance, satisfaction and strain. The study suggests that participative management may produce different results depending on teachers'…

  5. Student Participation - Simulation or Reality?

    DEFF Research Database (Denmark)

    Simovska, Venka

    2004-01-01

    This paper addresses the concept of student participation in learning processes within the health promoting schools approach. A model that distinguishes between token and genuine participation, which has been conceptualised on the basis of experience gained from the Macedonian Network of Health...

  6. Labour force participation and the feminising of the labour force

    OpenAIRE

    Brendan M. Walsh

    1992-01-01

    This paper studies the effects of changes in labour force particiapation rates on the size and structure of the Irish labour force over the period 1971-1991. The rise in participation rates among females aged 25-54 and the decline in participation among older and younger people of both sexes altered the structure of the labour force significantly. Time series of annual participation rates are used to explore the reasons for these changes. It is shown that participation rates among those aged ...

  7. Nurses' Journey Toward Genuine Participation

    DEFF Research Database (Denmark)

    Østergaard, Kija Lin; Simonsen, Jesper; Karasti, Teija Helena

    2016-01-01

    management has instructed them to do so, to taking an interest and finding their voices in the design process. In this way, they are ultimately able to engage in genuine and willing participation. The main discussion points in the paper are the transitions in the nurses' journey toward embracing qualities...... of genuine participation, the nurse-researcher's reflections on her facilitation of the process, and collective learning as an integral part of the process.......This paper contributes to the ongoing debate on participation in Participatory Design (PD) by drawing on the notion of genuine participation [8]. It clarifies nurses' empirical journey as one of becoming and learning [1, 6], where they move from being reluctant participants, attending only because...

  8. Youth Motivations for Program Participation

    Directory of Open Access Journals (Sweden)

    Jenifer K. McGuire

    2017-01-01

    Full Text Available Through their participation in youth programs, young people have access to opportunities to learn and build important skills. A total of 214 youth between the ages of 10-19 (mean 15.5 years completed an online survey about characteristics of youth programs they participated in, didn’t participate in, and had participated in but quit. We found that youth participated in activities that provided a benefit to meet personal goals or develop skills. However, our findings suggest that youth may leave activities, or never join them, based on different sets of motivations than the reasons they stay in activities. There was variability across demographic groups: Males reported more problems with past activities, sexual minority youth were more likely to endorse social problems with past and never joined activities, and ethnic minorities reported less support for personal goals and connection to adults in current activities and more logistic barriers for activities never joined.

  9. Leisure Sport Participation in Cyprus

    Directory of Open Access Journals (Sweden)

    Nicos Kartakoullis

    2015-12-01

    Full Text Available This study contributes to the limited existing research on the participation patterns of Cypriots in leisure and sports. Leisure and sport are viewed collectively while adapting the notion put forth by The Council of Europe (2007 defining leisure sports as sports activities aimed at the preservation and improvement of physical condition, health and fun. The purpose of this paper is to examine the leisure sport participation patterns of Cypriots, specifically: (1 participation patterns in leisure sports, (2 reasons for participating in leisure sports, (3 cost and participation in leisure sport, (4 leisure sport spectatorship, and (5 vacationing and leisure sport experiences. Data was commissioned and collected by the Centre for Leisure, Tourism and Sports (University of Nicosia for the Cyprus Sport Organisation. A telephone-survey of 1000 Cypriots, men and women, aged 15+, from coast-to-coast in Cyprus using stratified random sampling was employed. The sample was weighted by gender, age, district and region of residence. The results indicate that: (1 almost half of the Cypriot population participates in leisure sports, (2 participation in leisure sports decreases with age, (3 participation in leisure sports tends to be driven by health benefits, (4 most Cypriots participate in leisure sport at no cost, (5 television is the most common means reported for spectatorship, and (6 some Cypriots plan their vacations around leisure sport experiences. The results indicate the relevant importance of the leisure sport culture in Cyprus while also reflecting on age and cost related factors that may influence participation in leisure sports.

  10. The postanesthetic period. Complications.

    Science.gov (United States)

    Malamed, S F

    1987-01-01

    Postanesthetic complications can occur even in the best of circumstances. Proper preparation of the staff, aggressive monitoring of the recovering patient, and early recognition and management of the complications are essential if the outcome is to be successful. In reviewing postanesthetic complications, two factors are present in the overwhelming majority of situations--hypoxia and hypercarbia--often the direct result of inadequate monitoring during the postanesthetic period. The anesthetic procedure is not over once the anesthetic agents are discontinued. The skillful anesthetist is aware of the possibilities of postoperative complications and prevents problems by employing enhanced monitoring techniques during the recovery phase.

  11. Periodic Mesoporous Organosilica Nanorice

    Directory of Open Access Journals (Sweden)

    Mohanty Paritosh

    2008-01-01

    Full Text Available Abstract A periodic mesoporous organosilica (PMO with nanorice morphology was successfully synthesized by a template assisted sol–gel method using a chain-type precursor. The PMO is composed of D and T sites in the ratio 1:2. The obtained mesoporous nanorice has a surface area of 753 m2 g−1, one-dimensional channels, and a narrow pore size distribution centered at 4.3 nm. The nanorice particles have a length of ca. 600 nm and width of ca. 200 nm.

  12. Periods of Hecke characters

    CERN Document Server

    Schappacher, Norbert

    1988-01-01

    The starting point of this Lecture Notes volume is Deligne's theorem about absolute Hodge cycles on abelian varieties. Its applications to the theory of motives with complex multiplication are systematically reviewed. In particular, algebraic relations between values of the gamma function, the so-called formula of Chowla and Selberg and its generalization and Shimura's monomial relations among periods of CM abelian varieties are all presented in a unified way, namely as the analytic reflections of arithmetic identities beetween Hecke characters, with gamma values corresponding to Jacobi sums. The last chapter contains a special case in which Deligne's theorem does not apply.

  13. Periodic truss structures

    Science.gov (United States)

    Zok, Frank W.; Latture, Ryan M.; Begley, Matthew R.

    2016-11-01

    Despite the recognition of the enormous potential of periodic trusses for use in a broad range of technologies, there are no widely-accepted descriptors of their structure. The terminology has been based loosely either on geometry of polyhedra or of point lattices: neither of which, on its own, has an appropriate structure to fully define periodic trusses. The present article lays out a system for classification of truss structure types. The system employs concepts from crystallography and geometry to describe nodal locations and connectivity of struts. Through a series of illustrative examples of progressively increasing complexity, a rational taxonomy of truss structure is developed. Its conceptual evolution begins with elementary cubic trusses, increasing in complexity with non-cubic and compound trusses as well as supertrusses, and, finally, with complex trusses. The conventions and terminology adopted to define truss structure yield concise yet unambiguous descriptions of structure types and of specific (finite) trusses. The utility of the taxonomy is demonstrated by bringing into alignment a disparate set of ad hoc and incomplete truss designations previously employed in a broad range of science and engineering fields. Additionally, the merits of a particular compound truss (comprising two interpenetrating elementary trusses) is shown to be superior to the octet truss for applications requiring high stiffness and elastic isotropy. By systematically stepping through and analyzing the finite number of structure types identified through the present classification system, optimal structures for prescribed mechanical and functional requirements are expected to be ascertained in an expeditious manner.

  14. Participation & the power from within

    DEFF Research Database (Denmark)

    Andersen, Lars Bo; Danholt, Peter; Lauritsen, Peter

    for surveilling, controlling and caring for the wellbeing of placed children. Similarly, social workers are also obliged to include children as participants in their own case. To this end, social workers are dependent on intimate and trustworthy knowledge of children's everyday life. However, as Latour argued...... their removed from home. The observed situation thus complicates both the ambition of participation and the need for a surveillant welfare practice. Consequently, this paper explores three questions: a) how do social workers manage to surveil the wellbeing of children, b) how do children relate to social...... workers' surveillance, and c) how could we conceptualise the relation between welfare and surveillance in an age of participation....

  15. The Transformation of Employee Participation

    DEFF Research Database (Denmark)

    Busck, Ole Gunni; Knudsen, Herman; Lind, Jens

    2010-01-01

    This article reviews the research literature on the relationship between employee participation, influence and the work environment. The main part of the literature points to a positive connection in line with how it has been almost institutionalised in Karasek and Theorell´s demand control......-model. However, more recent research into psychosocial work environment problems questions the model’s assumption of high job control compensating for high job demands. Taking its point of departure in a `deconstruction´ of the concept of participation based on research on employee participation from the past...... few decades, the article discuss what factors and changes have resulted in that increased employee participation does not seem to result in a healthy work environment. The article concludes on the limitations of the demand control-model in modern working life given contextual changes in the employer-employee...

  16. Advancing the measurement of participation.

    Science.gov (United States)

    Whiteneck, Gale G; Bogner, Jennifer A; Heinemann, Allen W

    2011-04-01

    The authors of 3 articles in this issue have collaborated in an effort to advance the conceptualization and measurement of participation. These articles offer (1) a new tool for measuring participation, the Participation Assessment with Recombined Tools-Objective (PART-O), which combines items from widely used instruments in traumatic brain injury rehabilitation research; (2) 2 methods of scoring 17 items of PART-O, assessing relatively objective social role performance and yielding 3 subscale scores, as well as 2 alternative total scores (including 1 incorporating the concept of balance among types of participation), and (3) 19 enfranchisement items assessing the degree to which people with disability perceive they have the freedom to engage in social roles of their choosing while being accepted and valued by others.

  17. From Lurker to Active Participant

    NARCIS (Netherlands)

    Sloep, Peter; Kester, Liesbeth

    2009-01-01

    The original publication is available from www.springerlink.com. Sloep, P. B., & Kester, L. (2009). From Lurker to Active Participant. In R. Koper (Ed)., Learning Network Services for Professional Development (pp. 17-26). Berlin, Germany: Springer Verlag.

  18. Electronic Government and Electronic Participation

    NARCIS (Netherlands)

    Tambouris, E.; Scholl, H.J.; Janssen, M.F.W.H.A.; Wimmer, M.A.; Tarabanis, K.; Gascó, M.; Klievink, A.J.; Lindgren, I.; Milano, M.; Panagiotopoulos, P.; Pardo, T.A.; Parycek, P.; Sæbø, O.

    2015-01-01

    Electronic government and electronic participation continue to transform the public sector and society worldwide and are constantly being transformed themselves by emerging information and communication technologies. This book presents papers from the 14th International Federation for Information P

  19. Workplace mediation: the participant experience

    OpenAIRE

    Saundry, Richard; Bennett, Anthony Joseph William; Wibberley, Gemma

    2013-01-01

    This paper reports on a qualitative study of the perceptions and experiences of participants in workplace mediation. In total, 25 individuals, from a variety of occupations and organisations, were interviewed by researchers. The project sought to: explore the trajectory of individual disputes and assess participants’ views of the effectiveness of mediation provision and sustainability of outcomes. Furthermore, the research attempted to examine the broader impact of participation in mediation ...

  20. When Periodicities Enforce Aperiodicity

    Science.gov (United States)

    Bédaride, Nicolas; Fernique, Thomas

    2015-05-01

    Non-periodic tilings and local rules are commonly used to model the long range aperiodic order of quasicrystals and the finite-range energetic interactions that stabilize them. This paper focuses on planar rhombus tilings, which are tilings of the Euclidean plane, which can be seen as an approximation of a real plane embedded in a higher dimensional space. Our main result is a characterization of the existence of local rules for such tilings when the embedding space is four-dimensional. The proof is an interplay of algebra and geometry that makes use of the rational dependencies between the coordinates of the embedded plane. We also apply this result to some cases in a higher dimensional embedding space, notably tilings with n-fold rotational symmetry.

  1. Periods and Superstring Amplitudes

    CERN Document Server

    Stieberger, S

    2016-01-01

    Scattering amplitudes which describe the interaction of physical states play an important role in determining physical observables. In string theory the physical states are given by vibrations of open and closed strings and their interactions are described (at the leading order in perturbation theory) by a world-sheet given by the topology of a disk or sphere, respectively. Formally, for scattering of N strings this leads to N-3-dimensional iterated real integrals along the compactified real axis or N-3-dimensional complex sphere integrals, respectively. As a consequence the physical observables are described by periods on M_{0,N} - the moduli space of Riemann spheres of N ordered marked points. The mathematical structure of these string amplitudes share many recent advances in arithmetic algebraic geometry and number theory like multiple zeta values, single-valued multiple zeta values, Drinfeld, Deligne associators, Hopf algebra and Lie algebra structures related to Grothendiecks Galois theory. We review the...

  2. CYBER HOSTILITIES: CIVILIAN DIRECT PARTICIPATION

    Directory of Open Access Journals (Sweden)

    Dan-Iulian VOITAȘEC

    2016-06-01

    Full Text Available The manner in which hostilities are being conducted has changed in recent years. The battle field has transpired beyond the physical realm and now has a virtual component. Because of this, it is now easier than ever for civilians to get involved in hostilities. International Humanitarian Law applies to all situations of armed conflict and according to the principle of distinction, the parties to the conflict must, at all times, distinguish between civilians and combatants. The problem arises when the line between combatants and civilians starts to get blurry. Direct civilian participation in hostilities has been addressed in both Additional Protocols to the Geneva Conventions of 1949 and in 2009 the International Committee of the Red Cross published the Interpretive guidance on the notion of Direct Participation in Hostilities under international humanitarian law. Another document that addresses the problem of civilian direct participation is the Tallinn Manual on the International Law Applicable to Cyber Warfare prepared by an international group of experts at the invitation of the NATO Cooperative Cyber Defence Centre of Excellence in 2013. The guide prepared by the ICRC addresses the problem of civilian direct participation during conventional situations of armed conflict, while the Tallinn Manual addresses direct participation in situations of cyber warfare. The purpose of this paper is to study the application of civilian direct participation to situations of cyber warfare.

  3. [Childhood periodic syndromes].

    Science.gov (United States)

    Cuvellier, J-C; Lépine, A

    2010-01-01

    This review focuses on the so-called "periodic syndromes of childhood that are precursors to migraine", as included in the Second Edition of the International Classification of Headache Disorders. Three periodic syndromes of childhood are included in the Second Edition of the International Classification of Headache Disorders: abdominal migraine, cyclic vomiting syndrome and benign paroxysmal vertigo, and a fourth, benign paroxysmal torticollis is presented in the Appendix. The key clinical features of this group of disorders are the episodic pattern and intervals of complete health. Episodes of benign paroxysmal torticollis begin between 2 and 8 months of age. Attacks are characterized by an abnormal inclination and/or rotation of the head to one side, due to cervical dystonia. They usually resolve by 5 years. Benign paroxysmal vertigo presents as sudden attacks of vertigo, accompanied by inability to stand without support, and lasting seconds to minutes. Age at onset is between 2 and 4 years, and the symptoms disappear by the age of 5. Cyclic vomiting syndrome is characterized in young infants and children by repeated stereotyped episodes of pernicious vomiting, at times to the point of dehydration, and impacting quality of life. Mean age of onset is 5 years. Abdominal migraine remains a controversial issue and presents in childhood with repeated stereotyped episodes of unexplained abdominal pain, nausea and vomiting occurring in the absence of headache. Mean age of onset is 7 years. Both cyclic vomiting syndrome and abdominal migraine are noted for the absence of pathognomonic clinical features but also for the large number of other conditions to be considered in their differential diagnoses. Diagnostic criteria, such as those of the Second Edition of the International Classification of Headache Disorders and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, have made diagnostic approach and management easier. Their diagnosis

  4. Motivation and frustration in cardiology trial participation: the patient perspective

    Directory of Open Access Journals (Sweden)

    Silmara Meneguin

    2012-01-01

    Full Text Available OBJECTIVE: The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such studies, as well as those that led to participant frustration. METHODS: Patients who had participated in hypertension and coronary arterial disease (phases II, III, and IV clinical trials were invited to answer a questionnaire. They were divided into two groups: Group I, which included participants in placebo-controlled clinical trials after randomization, and Group II, which included participants in clinical trials in which the tested treatment was compared to another drug after randomization and in which a placebo was used in the washout period. RESULTS: Eighty patients (47 patients in Group I and 33 patients in Group II with different socio-demographic characteristics were interviewed. Approximately 60% of the patients were motivated to participate in the trial with the expectation of personal benefit. Nine participants (11.2% expressed the desire to withdraw, which was due to their perception of risk during the testing in the clinical trial (Group I and to the necessity of repeated returns to the institution (Group II. However, the patients did not withdraw due to fear of termination of hospital treatment. CONCLUSIONS: Although this study had a small patient sample, the possibility of receiving a benefit from the new tested treatment was consistently reported as a motivation to participate in the trials.

  5. 42 CFR 485.641 - Condition of participation: Periodic evaluation and quality assurance review.

    Science.gov (United States)

    2010-10-01

    ... member of the CAH staff who is a doctor of medicine or osteopathy or by another doctor of medicine or osteopathy under contract with the CAH; (4) The quality and appropriateness of the diagnosis and treatment furnished by doctors of medicine or osteopathy at the CAH are evaluated by— (i) One hospital that is...

  6. Enablers and constrainers to participation

    DEFF Research Database (Denmark)

    Desjardins, Richard; Milana, Marcella

    2007-01-01

    with constraining and enabling elements so as to raise participation among otherwise disadvantaged groups. To begin addressing this question, consideration is given to different types of constraints and different types of policies. These are brought together within a broad demand and supply framework, so...... as to construct a tool for analyzing the targeting of adult learning policy, with regard to both its coverage and expected consequences. Our aim is to develop a means for a more in-depth analysis of the match-mismatch of public policy and persisting constraints to participation....

  7. Entrepreneuriat Social et Participation Citoyenne

    Directory of Open Access Journals (Sweden)

    Sophie Larivet

    2010-01-01

    Full Text Available L'entrepreneuriat social est un concept émergeant, notamment dans les sciences de l'administration. Pourtant, en dehors d'une pratique directoriale spécifique, il est aussi une forme de participation citoyenne trop méconnue. L'objectif de cet article, basé sur une revue de la littérature et une approche théorique, est de présenter le concept d'entrepreneuriat social afin de mieux saisir son positionnement par rapport à la participation citoyenne. L'entrepreneuriat social constitue une forme particulière de participation à l'espace public par l'action, les entreprises sociales agissant au quotidien pour transformer le paysage social. En particulier, cet article souligne le contexte de développement de l'entrepreneuriat social, définit le concept et les notions connexes d'entreprise sociale et d'entrepreneur social, et, enfin, présente une réflexion sur la contribution de l'entrepreneuriat social à la participation citoyenne. L'article montre que l'entrepreneuriat social est une façon pour les citoyens d'agir directement et avec maîtrise sur la société. / Social entrepreneurship is an emerging concept, notably in administrative sciences. However, not only is it a specific managerial practice but it is also a type of citizen participation that is not well-known. The objective of this article, based on a literature review and a theoretical approach, is to present the concept of social entrepreneurship in order to better understand its relation to citizen participation. Social entrepreneurship represents a specific type of citizen participation involving actions. Social enterprises act daily to transform the social landscape. More specifically, this article presents the context of development of social entrepreneurship, proposes a definition of the concept and of other connected notions like "social enterprise" and "social entrepreneur", and, finally, analyzes the contribution of social entrepreneurship to citizen participation. It

  8. Scheduling participants of Assessment Centres

    DEFF Research Database (Denmark)

    Lysgaard, Jens; Løber, Janni

      Assessment Centres are used as a tool for psychologists and coaches to observe a number of dimensions in a person's behaviour and test his/her potential within a number of chosen focus areas. This is done in an intense course, with a number of different exercises which expose each participant...... Centres usually last two days and involve 3-6 psychologists or trained coaches as assessors. An entire course is composed of a number of rounds, with each round having its individual duration. In each round, the participants are divided into a number of groups with prespecifed pairing of group sizes...

  9. User Participation in Pilot Implementation

    DEFF Research Database (Denmark)

    Torkilsheyggi, Arnvør Martinsdóttir á; Hertzum, Morten

    2014-01-01

    implementation as a method for participatory design. We find that to foster participation and learning about user needs a pilot implementation must create a space for reflecting on use, in addition to the space for using the pilot system. The space for reflection must also exist during the activities preparing...... the use of the pilot system because the porters and nurses learned about their needs throughout the pilot implementation, not just during use. Finally, we discuss how the scope and duration of a pilot implementation influence the conditions for participation....

  10. Near periodicity in dynamical systems

    Institute of Scientific and Technical Information of China (English)

    陈文成

    1995-01-01

    The notion of near periodicity is shown to be equivalent to that of weak near periodicity in dynamical systems. A sufficient condition for the positive near periodicity of a point in dynamical systems is given. The structure of nearly periodic dynamical systems is discussed, and a condition is proved to be necessary and sufficient for a dynamical system on a local compact space to be positively nearly periodic.

  11. Periodicity-dependent stiffness of periodic hydrophilic-hydrophobic heteropolymers

    Science.gov (United States)

    Chowdhury, Debashish; Stauffer, Dietrich; Strey, Reinhard

    1999-08-01

    From extensive Monte Carlo simulations of a Larson model of perfectly periodic heteropolymers (PHP) in water, a striking stiffening is observed as the period of the alternating hydrophobic and hydrophilic blocks is shortened. At short period and low temperature needlelike conformations are the stable conformations. As temperature is increased thermal fluctuations induce kinks and bends. At large periods compact oligomeric globules are observed. From the generalized Larson prescription, originally developed for modeling surfactant molecules in aqueous solutions, we find that the shorter the period is the more stretched the PHP is. This novel effect is expected to stimulate polymer synthesis and trigger research on the rheology of aqueous periodic heteropolymer solutions.

  12. THE WAVELET TRANSFORM OF PERIODIC FUNCTION AND NONSTATIONARY PERIODIC FUNCTION

    Institute of Scientific and Technical Information of China (English)

    刘海峰; 周炜星; 王辅臣; 龚欣; 于遵宏

    2002-01-01

    Some properties of the wavelet transform of trigonometric function, periodic function and nonstationary periodic function have been investigated. The results show that the peak height and width in wavelet energy spectrum of a periodic function are in proportion to its period. At the same time, a new equation, which can truly reconstruct a trigonometric function with only one scale wavelet coefficient, is presented. The reconstructed wave shape of a periodic function with the equation is better than any term of its Fourier series. And the reconstructed wave shape of a class of nonstationary periodic function with this equation agrees well with the function.

  13. Cultural participation and tourism flows

    DEFF Research Database (Denmark)

    Borowiecki, Karol Jan; Castiglione, Concetta

    2014-01-01

    The importance of cultural events for attracting tourism has often been posited in research, but rarely rested in relation to non-cultural activities. This paper investigates the association between participation in entertainment activities and tourism flows in Italian provinces, and finds...

  14. Health and Labor Force Participation

    Science.gov (United States)

    Berkowitz, Monroe; Johnson, William G.

    1974-01-01

    Analytic labor force participation models which exclude information on worker health care lack explanatory power. If costs of disability can be separated through better information into costs reducible through delivery of health care, and costs more appropriately dealt with through labor market policies, the models will be improved. (KP)

  15. Community consensus: Design beyond participation

    CSIR Research Space (South Africa)

    Winschiers-Theophilus, H

    2012-07-01

    Full Text Available as "the designer from within" and "the technologist/researcher/designer" as the "designer from outside" not originating from the community in which the design takes place. In this article, we propose that grappling with meanings about participation...

  16. From Silent to Talkative Participants

    DEFF Research Database (Denmark)

    Nielsen, Kurt Aagaard; Olsén, Peter; Nielsen, Birger Steen

    1996-01-01

    are sceptical as to the ability of this tradition to explain the fact that workers are silent participants in negotiations. In an account of a project called 'Industry and Happiness' the authors argue that attention must be paid to workers' life situation and not only to their work experience. They further...

  17. Fostering Participation and Leadership Skills

    Science.gov (United States)

    Jaiswal, Preeti

    2006-01-01

    Schools play a very significant role in fostering participation and leadership skills and in promoting the way forward to a better future. This article offers a number of strategies which can pave developmental pathways to student leadership. In addition, it analyses the beneficial aspects of such activities in enhancing the competency of students…

  18. Emergency Exercise Participation and Evaluation

    Science.gov (United States)

    Smith, Julie; Black, Lynette; Williams, Linda

    2012-01-01

    Extension is uniquely positioned to participate in emergency exercises, formally or informally, with the goal of engaging community members in emergency and disaster preparedness. With their knowledge of community needs, Extension personnel are valuable resources and can assist emergency managers in the process of identifying local risks and…

  19. Editorial: Enterprise Participation (January 2009

    Directory of Open Access Journals (Sweden)

    Donald Smith

    2009-01-01

    Full Text Available In The Role of Participation Architecture in Growing Sponsored Open Source Communities, Joel West and Siobhan O'Mahony argue that "to some extent, firms and technical communities have always collaborated to create standards, shared infrastructure, and innovation outcomes that are bigger than any one firm can achieve." and that "there is increasing evidence that path breaking innovations cannot occur without a community to interpret, support, extend and diffuse them". When considered in this light, it should not be surprising that more enterprises, both large and small, are increasing their participation in open source communities to drive innovation. The theme for this month's issue of the OSBR is enterprise participation and the authors provide practical advice for effective enterprise/community collaboration. Their experiences provide perspectives on: i the Eclipse Foundation, which maintains an ecosystem of over 150 enterprises that participate in Eclipse open source projects; ii an independent software vendor that sells closed source solutions constructed on top of an open source platform to large enterprise customers; iii the impact of major players collaborating on a common open source platform for the mobile industry; iv the role users can play in the very large (over 14 million GNOME community; and v the lessons a scientist from the National Research Council of Canada learned when he released software and started a small open source community.

  20. Citizen Participation: Antagonists or Allies

    Science.gov (United States)

    Cunningham, William G.

    1976-01-01

    If participation does not include an openness to the issues that are of real concern to the community and an opportunity to influence policy relating to those issues, it becomes an empty public relations gesture fostering apathy, disinterest, resistance, or counter-organization. (MB)

  1. Design Participation As Postdramatic Theatre

    DEFF Research Database (Denmark)

    Ryöppy, Merja; Lima, Patricia; Buur, Jacob

    2015-01-01

    In our struggle to better understand and fa cilitate design participation we have turned our attention to the novel genre of Postdramatic Theatre (Lehmann 2006). In particular, this paper explores the intersections between Postdramatic Theatre and Participatory Innovation (Buur & Mathews 2008). Two...

  2. Complement's participation in acquired immunity

    DEFF Research Database (Denmark)

    Nielsen, Claus Henrik; Leslie, Robert Graham Quinton

    2002-01-01

    in which antigen is seen, be it alone or in association with natural or induced antibodies and/or C3-complement fragments. The aim of this review is to describe the present status of our understanding of complement's participation in acquired immunity and the regulation of autoimmune responses....

  3. Persistence in periodic and almost periodic Lotka-Volterra systems.

    Science.gov (United States)

    Gopalsamy, K

    1984-01-01

    It is shown that a strongly self-regulating (or resource limited) Lotka-Volterra population system can "persist" in a periodic or almost periodic environment if and only if the system tracks the environmental variations.

  4. Comparison of modified atmosphere packaging and vacuum packaging for long period storage of dry-cured ham: effects on colour, texture and microbiological quality

    OpenAIRE

    Garcia-Esteban, M. (Marta); Ansorena, D. (Diana); Astiasarán, I. (Iciar)

    2004-01-01

    Slices of dry-cured hams (Biceps femoris muscle) were stored during 8 weeks under vacuum and modified atmospheres (100% N2 and a mixture of 20% CO2 and 80% N2) in order to study the modifications on colour, texture and microbial counts during that period. Lightness was found to be more stable when samples were stored with 20% CO2 and 80% N2 without statistical differences between vacuum and 100% N2. A slight whiteness was observed in the vacuum packed samples. Yellowness increased during time...

  5. Photolysis of Periodate and Periodic Acid in Aqueous Solution

    DEFF Research Database (Denmark)

    Sehested, Knud; Kläning, U. K.

    1978-01-01

    The photochemistry of periodate and periodic acid in aqueous solution was studied (i) by quantum yield measurements at low light intensity (ii) by flash photolysis, and (iii) by photolysis of glassy samples at 77 K. The photochemical studies were supplemented with pulse radiolysis studies...... of aqueous periodate solutions and with kinetic studies using stopped-flow technique. In strongly alkaline solution the photodecomposition of periodate proceeds via formation of O– and IVI. At pH

  6. Can Lay Community Advisors Improve the Clarity of Research Participant Recruitment Materials and Increase the Likelihood of Participation?

    Science.gov (United States)

    Bowers, Barbara; Jacobson, Nora; Krupp, Anna

    2017-02-01

    Despite decades of effort, lower income people and ethnic minorities continue to be underrepresented as participants in health research. A group of racially and ethnically diverse, lower income community members (Community Advisors on Research Design and Strategies: CARDS®) was trained to review study designs and procedures and provide recommendations to researchers for increasing participation and making research materials more understandable to members of underrepresented communities. In this mixed methods study, one participant group (n = 55) was shown research materials (recruitment documents and a consent form) developed by a research team and approved by the local IRB. A second group (n = 45) was shown the same materials after they had also been reviewed and revised by CARDS. Interviews, which included both fixed-response and open-ended questions, were used to assess reactions of participants in both groups to the materials, including their hypothetical willingness to volunteer for the research described. Group differences were examined using the Chi-square distribution test. Proportional difference effect sizes were estimated using arcsine transformation. The qualitative data were subjected to conventional content analysis. Participants in the group shown the recruitment materials revised by CARDS were more likely to say they understood the documents, more likely to ask for more information about the study, and more likely to say they would participate in the research. Results of content analysis suggested a four-phase sequential process for deciding whether to participate in the research. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  7. Periodic feedback stabilization for linear periodic evolution equations

    CERN Document Server

    Wang, Gengsheng

    2016-01-01

    This book introduces a number of recent advances regarding periodic feedback stabilization for linear and time periodic evolution equations. First, it presents selected connections between linear quadratic optimal control theory and feedback stabilization theory for linear periodic evolution equations. Secondly, it identifies several criteria for the periodic feedback stabilization from the perspective of geometry, algebra and analyses respectively. Next, it describes several ways to design periodic feedback laws. Lastly, the book introduces readers to key methods for designing the control machines. Given its coverage and scope, it offers a helpful guide for graduate students and researchers in the areas of control theory and applied mathematics.

  8. Women, Participation and the European Parliament

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene; Agustin, Lise Rolandsen

    2013-01-01

    The European Parliament (EP) as an institution can be understood as having the potential for becoming ‘a strong public’ which is undergoing a process of building a wider general public: ‘The EP can be conceived of as an incipient transnational public sphere’ (Liebert 2007: 268). This makes the EP...... (Ferree et al. 2002) by looking both at the gender composition of the EP and the framing of debates about women´s representation within the EP and its Committee on Women’s Rights and Gender Equality (FEMM) during the period 2000-2011....... an apt institutional setting for analyzing both women´s descriptive representation within it, as well as analyzing the debates about women´s representation, in politics and business, which are taking place within the EP. We thus conduct a two-pronged analysis of the who of public sphere participation...

  9. Innovative forms of citizen participation

    DEFF Research Database (Denmark)

    Nyseth, Torill; Ringholm, Toril; Agger, Annika

    Formal procedures of citizen participation in planning and urban governance in Norway and Denmark share many similarities. Although the planning laws are intended to give all affected stakeholders a chance to air their concerns within a limited time frame, then few use these channels for voice......: What characterises the new and innovative forms of citizen participation in urban planning in terms of innovation? And in what ways and to what degree is input from these processes fed into the formal planning processes? Theoretically, the paper is inspired by the concept of: ‘planning...... interact within the field of urban governance. This is for example seen in urban regeneration projects in Denmark and planning experiments in Norway where we are witnessing more inclusive and bottom-up initiated interactions between public authorities and local actors. The key question in this paper is...

  10. Social Happiness and Social Participation

    Directory of Open Access Journals (Sweden)

    2015-06-01

    Full Text Available Introduction   Social happiness is part of the social welfare component and depends more on social and economic determinants than on psychological and medical interventions. Meanwhile , it is one of the core concepts of sustainable development. Being happy is just one of the desirable wishes of life in every society . A nation is fresher and certainly wealthier when its citizens are happy. In this type of society , citizens have optimistic attitudes towards life and things around them. From 2000 onwards, variables such as happiness, hope in future , pleasure and satisfaction have been included as key variables in UN debates to determine level of development s in countries . This phenomenon is measured by the density of social networks and relationships , in many studies is associated with social health and happiness (Kawachi, 2008. Durkheim showed that suicide rates in populations with low levels of participation and social cohesion were more than cohesive communities (Halpern, 2005. Theorists argue that when people reach to a desired location or target , they become happy . According to Lerner, new communities are participatory societies in which modernization process is advanced , a move from traditional society to participatory society is inevitable. In t his view, economic participation means increased activity in the market and an increase in income, political participation means participation in elections , cultural participation means utilization of mass media and emotional involvement means empathy and psychological mobility (Lerner 1969: 86 .     Materials & Methods   This is quantitative study based on survey. We used Descriptive statistics and indicators such as dispersion and mean , standard deviation , minimum and maximum scores. For inferential statistics and to test the hypotheses, we used Pearson 's correlation coefficient and analysis of variance . A lso for explaining the social happiness variable , a stepwise multiple

  11. Personality, Negativity, and Political Participation

    Directory of Open Access Journals (Sweden)

    Aaron C. Weinschenk

    2014-08-01

    Full Text Available Scholars have recently started to integrate personality traits into models of political participation. In this paper, we present the results of a survey experiment (N = 724 designed to test whether negative political messages differentially impact people with different personality traits. We found evidence that individuals with high scores on agreeableness were less likely, and individuals with high scores on extraversion were more likely, to report intending to participate in politics than their counterparts after being exposed to negative political messages. Agreeableness and extraversion also interacted with negative messages to influence specific intentions to make a political donation, attend a meeting, rally, or event, and volunteer for a political campaign. We also found suggestive evidence that agreeableness interacted with negativity to influence turnout intentions. The results of this study have important implications for the study of political engagement, the ways in which people interact with political information, and the practice of democratic politics.

  12. Participation patterns in adult education

    DEFF Research Database (Denmark)

    Desjardins, Richard; Rubenson, Kjell

    2013-01-01

    of investment in the development and maintenance of skills over the lifespan of individuals is to a large extent interconnected with a high-level of non-market coordination via institutional arrangements and/or specific public policy measures. Such arrangements and measures are seen to alleviate coordination......This article focuses on evidence regarding cross-national patterns of participation in adult education and an interpretation of these patterns from an institutional and public policy perspective. The interpretation follows from the perspective that sustaining high and widely distributed levels...... problems that otherwise lead to underinvestment in skills and/or inequity in the distribution of access to education and training and hence skills. Hence, it is argued that institutional contexts and public policy measures condition participation patterns in adult education, and are thus worthwhile...

  13. The redoubtable ecological periodic table

    Science.gov (United States)

    Ecological periodic tables are repositories of reliable information on quantitative, predictably recurring (periodic) habitat–community patterns and their uncertainty, scaling and transferability. Their reliability derives from their grounding in sound ecological principle...

  14. The redoubtable ecological periodic table

    Science.gov (United States)

    Ecological periodic tables are repositories of reliable information on quantitative, predictably recurring (periodic) habitat–community patterns and their uncertainty, scaling and transferability. Their reliability derives from their grounding in sound ecological principle...

  15. Doubly Resonant Optical Periodic Structure.

    Science.gov (United States)

    Alagappan, G; Png, C E

    2016-02-08

    Periodic structures are well known in various branches of physics for their ability to provide a stopband. In this article, using optical periodic structures we showed that, when a second periodicity--very closed to the original periodicity is introduced, large number of states appears in the stopband corresponding to the first periodicity. In the limit where the two periods matches, we have a continuum of states, and the original stopband completely disappears. This intriguing phenomena is uncovered by noticing that, regardless of the proximities of the two periodicities, there is an array of spatial points where the dielectric functions corresponding to the two periodicities interfere destructively. These spatial points mimic photonic atoms by satisfying the standards equations of quantum harmonic oscillators, and exhibit lossless, atom-like dispersions.

  16. Participation and Interaction in Foresight

    DEFF Research Database (Denmark)

    This ibook combines theory and practice to analyse the experiences and impacts of foresight activities in various European countries. It includes case studies with a focus on different societal issues including national development, science and technology, and sustainable development. The book...... describes and analyses foresight projects carried out in countries at various stages of economic development including mature market economies, transition economies and young democracies. The book includes theoretical chapters on stakeholder participation, negotiation and dialogue, learning, and visioning...

  17. Participative Design With Top Management

    DEFF Research Database (Denmark)

    Simonsen, Jesper

    2004-01-01

    meetings aimed at aligning top management with the supplier’s analysis. The article describes the MUST method’s anchoring principle and the technique of problem mapping supporting this principle. This participatory approach resulted in mutual learning processes with top management which is rarely reported...... on in the PD community. Top management participated by reviewing, challenging, and reformulating the IT designers’ central suppositions, assumptions, and hypotheses related to the causal relation between identified problems and suggested solutions....

  18. Periodic review and continuous ordering

    OpenAIRE

    Prak, Dennis R.J.; Teunter, Ruud; Riezebos, Jan

    2014-01-01

    There exist many inventory control studies that consider either continuous review & continuous ordering, or periodic review & periodic ordering. Mixtures of the two are hardly ever studied. However, the model with periodic review and continuous ordering is highly relevant in practice, as information on the actual inventory level is not always up to date while making ordering decisions. This paper will therefore consider this case of periodic review and continuous ordering. Assuming zero fixed...

  19. 7 CFR 17.4 - Agents of the participant or importer.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Agents of the participant or importer. 17.4 Section 17... Agents of the participant or importer. (a) General. (1) A participant or importer is not required to use... importer and such agent. The written nomination shall also specify the period of time to be covered by...

  20. Sport Education and Extracurricular Sport Participation: An Examination Using the Trans-Contextual Model of Motivation

    Science.gov (United States)

    Wallhead, Tristan L.; Hagger, Martin; Smith, Derek T.

    2010-01-01

    In this study, we used the trans-contextual model of motivation (TCM) to examine the effect of Sport Education (SE) on students' participation in a voluntary lunch recess sport club. A total of 192 participants (ages 9-14 years) completed measures of the TCM constructs before and after a 12-week SE intervention period. Participants had the…

  1. Sport Education and Extracurricular Sport Participation: An Examination Using the Trans-Contextual Model of Motivation

    Science.gov (United States)

    Wallhead, Tristan L.; Hagger, Martin; Smith, Derek T.

    2010-01-01

    In this study, we used the trans-contextual model of motivation (TCM) to examine the effect of Sport Education (SE) on students' participation in a voluntary lunch recess sport club. A total of 192 participants (ages 9-14 years) completed measures of the TCM constructs before and after a 12-week SE intervention period. Participants had the…

  2. Periodic review and continuous ordering

    NARCIS (Netherlands)

    Prak, Dennis; Teunter, Ruud; Riezebos, Jan

    2015-01-01

    Many inventory control studies consider either continuous review and continuous ordering, or periodic review and periodic ordering. Mixtures of the two are hardly ever studied. However, the model with periodic review and continuous ordering is highly relevant in practice, as information on the actua

  3. Periodic review and continuous ordering

    NARCIS (Netherlands)

    Prak, Dennis R.J.; Teunter, Ruud; Riezebos, Jan

    2014-01-01

    There exist many inventory control studies that consider either continuous review & continuous ordering, or periodic review & periodic ordering. Mixtures of the two are hardly ever studied. However, the model with periodic review and continuous ordering is highly relevant in practice, as information

  4. Periodic review and continuous ordering

    NARCIS (Netherlands)

    Prak, Dennis R.J.; Teunter, Ruud; Riezebos, Jan

    2014-01-01

    There exist many inventory control studies that consider either continuous review & continuous ordering, or periodic review & periodic ordering. Mixtures of the two are hardly ever studied. However, the model with periodic review and continuous ordering is highly relevant in practice, as information

  5. Periodic review and continuous ordering

    NARCIS (Netherlands)

    Prak, Dennis; Teunter, Ruud; Riezebos, Jan

    2015-01-01

    Many inventory control studies consider either continuous review and continuous ordering, or periodic review and periodic ordering. Mixtures of the two are hardly ever studied. However, the model with periodic review and continuous ordering is highly relevant in practice, as information on the

  6. [Trends in female economic participation in the 1980s].

    Science.gov (United States)

    Pedrero Nieto, M

    1990-01-01

    The author analyzes trends in female labor force participation by age in Mexico during the period 1978-1987, using data for Mexico City, Monterrey, and Guadalajara. Aspects considered include the increase in the number of employed married women, changes in type of occupational activity, and changes in the motivations for women seeking employment, especially changes due to the need for additional household income.

  7. Female labour force participation and fertility.

    Science.gov (United States)

    Concepcion, M B

    1974-01-01

    The levels of labor force participation by women in selected Asian countries were recorded in a series of censuses taken over a period of years. These levels were less influenced than male employment levels by economic conditions and more influenced by cultural traits of the country. Postwar trends seem to have fallen in Korea, risen in Singapore and the Philippines, and remained steady in Japan, Malaya, and Thailand. The limitations of these data are mentioned. In Thailand and West Malaysia greater percentages of women worked in agricultural than non-agricultural employment; in the Philippines, where women did not work so much in agricultural pursuits, their jobs were still in traditional rather than in development industries. In the cities of Bangkok, Manila, and Kuala Lumpur, fertility was lower for working than for non-working women. In rural agricultural areas, the fertility of working women was minimally higher, probably due to economic need of lar ger families. It is concluded that urban life separates the employment and the family roles of working women, leading to lowered fertility; this does not occur in rural areas. The creation of new roles for women alternative or supplementary to marriage and motherhood would result in lowered fertility. In high fertility Asian countries, policies directed toward greater participation of women in non-agricultural work and great er exposure to an urban lifestyle might achieve fertility reductions.

  8. Midy's Theorem for Periodic Decimals

    OpenAIRE

    Lewittes, Joseph

    2006-01-01

    The decimal expansion of 1/7 is 0.142857142857..., the block 142857 repeating forever. We call 142857 the period and its length is 6 = 2x3. If the period is broken into 2 pieces each of length 3 which are then added, the result is 142 + 857 = 999; similarly 14 + 28 + 57 = 99. Other periodic decimals show the same phenomenon while others do not. The general question then arises: Let a/N be a fraction with denominator prime to 10, having decimal expansion with period length dk, if the period is...

  9. Evaluating participation in water resource management: A review

    Science.gov (United States)

    Carr, G.; BlöSchl, G.; Loucks, D. P.

    2012-11-01

    Key documents such as the European Water Framework Directive and the U.S. Clean Water Act state that public and stakeholder participation in water resource management is required. Participation aims to enhance resource management and involve individuals and groups in a democratic way. Evaluation of participatory programs and projects is necessary to assess whether these objectives are being achieved and to identify how participatory programs and projects can be improved. The different methods of evaluation can be classified into three groups: (i) process evaluation assesses the quality of participation process, for example, whether it is legitimate and promotes equal power between participants, (ii) intermediary outcome evaluation assesses the achievement of mainly nontangible outcomes, such as trust and communication, as well as short- to medium-term tangible outcomes, such as agreements and institutional change, and (iii) resource management outcome evaluation assesses the achievement of changes in resource management, such as water quality improvements. Process evaluation forms a major component of the literature but can rarely indicate whether a participation program improves water resource management. Resource management outcome evaluation is challenging because resource changes often emerge beyond the typical period covered by the evaluation and because changes cannot always be clearly related to participation activities. Intermediary outcome evaluation has been given less attention than process evaluation but can identify some real achievements and side benefits that emerge through participation. This review suggests that intermediary outcome evaluation should play a more important role in evaluating participation in water resource management.

  10. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying

    2012-02-01

    This article proposes a nonparametric method for estimating the period and values of a periodic sequence when the data are evenly spaced in time. The period is estimated by a "leave-out-one-cycle" version of cross-validation (CV) and complements the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both theoretically and by simulation.We also propose a nonparametric test of the null hypothesis that the data have constantmean against the alternative that the sequence of means is periodic. Finally, our methodology is demonstrated on three well-known time series: the sunspots and lynx trapping data, and the El Niño series of sea surface temperatures. © 2012 American Statistical Association and the American Society for Quality.

  11. Positive periodic solutions of delayed periodic Lotka-Volterra systems

    Energy Technology Data Exchange (ETDEWEB)

    Lin Wei [Laboratory of Nonlinear Mathematics Science, Institute of Mathematics, Fudan University, Shanghai 200433 (China)]. E-mail: weilin@fudan.edu.cn; Chen Tianping [Laboratory of Nonlinear Mathematics Science, Institute of Mathematics, Fudan University, Shanghai 200433 (China)]. E-mail: tchen@fudan.edu.cn

    2005-01-17

    In this Letter, for a general class of delayed periodic Lotka-Volterra systems, we prove some new results on the existence of positive periodic solutions by Schauder's fixed point theorem. The global asymptotical stability of positive periodic solutions is discussed further, and conditions for exponential convergence are given. The conditions we obtained are weaker than the previously known ones and can be easily reduced to several special cases.

  12. Therapeutic elements in a self-management approach: experiences from group participation among people suffering from chronic pain.

    Science.gov (United States)

    Furnes, Bodil; Natvig, Gerd Karin; Dysvik, Elin

    2014-01-01

    Chronic pain is a complex, multifaceted subjective experience that involves the whole person. Self-management is the dynamic and continuous process of adapting one's situation to the cognitive, behavioral, and emotional responses necessary to maintain a satisfactory quality of life. Approaches based on cognitive behavioral therapy (CBT) are described as appropriate in assisting people suffering from chronic pain because they challenge maladaptive beliefs and behaviors in relation to pain. This study aimed to explore patients' experiences of therapeutic elements from group participation in a chronic pain management program. A qualitative research design with a phenomenological hermeneutic approach was used. Six months after participation in the 8-week course, 34 participants formulated and submitted written reports based on open-ended questions related to their group participation and self-help achievement. These reports were analyzed by elements of qualitative content analysis. THE ANALYSIS RESULTED IN TWO SUBTHEMES: "The significance of active involvement in gaining new insight" and "The significance of community and group support." These were abstracted in the main theme: "Successful self-management is related to several significant contributions in the group." An active role with writing, self-revelation, and exchanges of thoughts and feelings in the group seemed to be the key tools for success. In addition, group support and access to other group members' experiences were significant therapeutic elements. We suggest that successful self-management requires knowledge of essential therapeutic elements. In a CBT-based group approach, such elements may offer an important health care contribution.

  13. What deters nurses from participating in web-based graduate nursing programs?: A cross-sectional survey research study.

    Science.gov (United States)

    Carpenter, Suzanne H

    2016-01-01

    A graduate degree is required of nursing faculty in America. Because of the nursing faculty shortage, web-based graduate nursing programs are being offered to encourage nurses to return to school. The identification of deterrents to participating in these programs is an important step in increasing enrollment. To identify deterrents to participation in web-based graduate nursing programs. Descriptive survey research. Louisiana Two hundred and eighty-one registered nurse members of the Louisiana Nurses' Association. The 54-item four-point Likert-type interval scale Deterrents to Participation in Web-Based Graduate Nursing Programs Survey Instrument was used. Data were collected over 8weeks using SurveyMonkey.com to administer the web survey tool to all members of the Louisiana State Nurses' Association. A factor analysis revealed a three-factor solution that explained 55.436% of the total variance in deterrents to participation in web-based graduate nursing programs. The factors were labeled "concerns about quality, cost, and time," "concerns about access to resources: technological and personal," and "concerns about electronic mediated communication." Multiple regression analysis revealed an overall model of three predictors of deterrents to participation in web-based graduate nursing programs: no computer literacy, annual household income between 20,000 and 50,000 dollars, and having the current educational status of graduating from a diploma RN program. This model accounted for 21% of the variance in the deterrents to participation scores. Since these three significant predictors of deterrents to participation in web-based graduate nursing programs were identified, web-based nursing graduate program administrators might consider an outreach to RN diploma graduates in an effort to make them aware of available technology support programs to foster participation. Scholarships for lower income nursing students are recommended, and programs to support computer

  14. Methane and Carbon Dioxide Emissions from Different Composting Periods

    Directory of Open Access Journals (Sweden)

    Cheng-Hsiung Chang

    2009-01-01

    Full Text Available To investigate green house gas emissions from compost preparations, methane and carbon dioxide concentrations and emission rates at different accumulative times and composting periods were determined. While the accumulative time was less than 10 min with a closed acrylic chamber, meth ane and carbon dioxide emissions in creased slightly but with high fluntuation in the sampling e ror, and these values decreased significantly when the accumulative time was more than 20 min. During the 8 weeks of composting, the methane emission rate reaches its peak near the end of the second week and the carbon dioxide emission rate does the same near the end of third week. Meth ane and carbon dioxide emissions had high val ues at the first stage of com post ing and then de creased grad u ally for the ma tu rity of com post. Carbon dioxide emission (y was significantly related to temperature (x1, moisture content (x2, and total or ganiccarbon (x3; and there gression equation is: y = 3.11907x1 + 6.19236x2 - 6.63081x3 - 50.62498. The re gres sion equa tion be tween meth ane emis sion (y? and mois ture con tent (x2, pH (x4, C/N ra tio (x5, and ash con tent (x6 is: y?= 0.13225x2 - 0.97046x4 - 1.10599x5 - 0.55220x6 + 50.77057 in the ini tial com post ing stage (weeks 1 to 3; while, the equa tion is: y?= 0.02824x2 - 0.0037x4 - 0.1499x5 - 0.07013x6 + 4.13589 in the later compost ing stage (weeks 4 to 8. Dif ferent stage composts have significant variation of properties and greenhouse gas emissions. Moreover, the emissions may be reduced by manipulating the proper factors.

  15. [Periodic breathing with periodic oxygen variation in infancy].

    Science.gov (United States)

    von Czettritz, G; Bax, R T; Eckardt, T; Springer, S; Emmrich, P

    1996-01-01

    Oxycardiorespirographies, recording arterial oxygen saturation (SaO2), breathing movements, heart rate and ECG with a mean recording time of 22.3 hours, were performed on 85 preterm (mean postconceptional age: 38 weeks) and 81 term infants (mean postconceptional age 42.4 weeks). 83% of the preterm infants showed periodic breathing (PB), in 97% of them this was accompanied by periodic variations of arterial oxygen saturation (PVO). Periodic breathing occurred in 61% of the term infants, 84% of them showed PVO during periodic breathing. The mean variation of oxygen saturation was between 92.8 and 96.8% (+/- 1.7) for preterm and between 92.9 and 96.0% (+/- 2.2) for term infants. In some infants the peak to peak amplitude of the SaO2 cycles was up to 22%, sometimes a further fall of SaO2 occurred. There was a strong correlation of the PVO both at the beginning and end of the episode as well as with the PB-cycle periodicity itself. The fall of the oxygen saturation occurred 3.1 to 7.8 s after the beginning of the first apnea of an episode of periodic breathing, the minimum SaO2 was reached approximately 4.2 to 8.6 s later. This periodic rapid fall of SaO2 from a high oxygenation level cannot be explained by the apneas of a rather short duration during periodic breathing. It is discussed that PVO during periodic breathing may be caused by an ideopathic right to left shunting across fetal circulation pathways which occurs intermittently and periodically. This mechanism could-via patterns of reaction exhibited during the fetal and neonatal time period-lead to acute hypoxemia, as found in apparently life threatening events (ALTE) and as postulated in sudden infant death (SID).

  16. Repelling periodic points of given periods of rational functions

    Institute of Scientific and Technical Information of China (English)

    CHANG Jianming; FANG Mingliang

    2006-01-01

    Let R(z) be a rational function of degree d ≥ 2. Then R(z) has at least one repelling periodic point of given period k ≥ 2, unless k = 4 and d=2, or k= 3 and d ≤ 3, or k=2 and d≤8. Examples show that all exceptional cases occur.

  17. From Periodic Properties to a Periodic Table Arrangement

    Science.gov (United States)

    Besalú, Emili

    2013-01-01

    A periodic table is constructed from the consideration of periodic properties and the application of the principal components analysis technique. This procedure is useful for objects classification and data reduction and has been used in the field of chemistry for many applications, such as lanthanides, molecules, or conformers classification.…

  18. From Periodic Properties to a Periodic Table Arrangement

    Science.gov (United States)

    Besalú, Emili

    2013-01-01

    A periodic table is constructed from the consideration of periodic properties and the application of the principal components analysis technique. This procedure is useful for objects classification and data reduction and has been used in the field of chemistry for many applications, such as lanthanides, molecules, or conformers classification.…

  19. On the Period-Amplitude and Amplitude-Period Relationships

    Science.gov (United States)

    Wilson, Robert M.; Hathaway, David H.

    2008-01-01

    Examined are Period-Amplitude and Amplitude-Period relationships based on the cyclic behavior of the 12-month moving averages of monthly mean sunspot numbers for cycles 0.23, both in terms of Fisher's exact tests for 2x2 contingency tables and linear regression analyses. Concerning the Period-Amplitude relationship (same cycle), because cycle 23's maximum amplitude is known to be 120.8, the inferred regressions (90-percent prediction intervals) suggest that its period will be 131 +/- 24 months (using all cycles) or 131 +/- 18 months (ignoring cycles 2 and 4, which have the extremes of period, 108 and 164 months, respectively). Because cycle 23 has already persisted for 142 months (May 1996 through February 2008), based on the latter prediction, it should end before September 2008. Concerning the Amplitude-Period relationship (following cycle maximum amplitude versus preceding cycle period), because cycle 23's period is known to be at least 142 months, the inferred regressions (90-percent prediction intervals) suggest that cycle 24's maximum amplitude will be about less than or equal to 96.1 +/- 55.0 (using all cycle pairs) or less than or equal to 91.0 +/- 36.7 (ignoring statistical outlier cycle pairs). Hence, cycle 24's maximum amplitude is expected to be less than 151, perhaps even less than 128, unless cycle pair 23/24 proves to be a statistical outlier.

  20. Crowdsourcing. A Citizen Participation Challenge

    Directory of Open Access Journals (Sweden)

    Junia Borges

    2014-05-01

    Full Text Available This paper is a work in progress on Crowdsourcing. First, its concepts and importance are discussed and then its value for citizenship and urban planning. The motivation for participation and the display of geo-tagged information, as well as its possible applications in dynamic spatial temporal issues are presented, as well as its different approaches and applications. Furthermore, Crowdsourcing is discussed when the “ONVCêVIU”, a VGI case study, is presented, revealing its origin, objective, free platform comparison - to select the proper tool to implement, the project’s main challenges, results so far and further steps to be taken. To conclude a short review of the author’s vision about what is to come in the future research.

  1. Democratic Theory and Citizen Participation

    DEFF Research Database (Denmark)

    Biegelbauer, Peter; Hansen, Janus

    2011-01-01

    Citizen participation in terms of participatory technology assessment (PTA) has caused a lot of debate in science and technology policy. However, there are still many open questions: What is the actual impact of PTA on policy-making? On which normative theory of democracy is the evaluation of PTA...... based and does it make a difference which theory is used? Which framework is appropriate to evaluate the often fuzzy impact of PTA on policy-making? Is PTA actually a central element for policy-making or are other factors much more relevant such as politicians' involvement or the presence of industry...... interests? What is the ‘nature’ of the public in different national and institutional contexts? How are expectations of policy-makers played out in the perceived need for regulation? These issues are addressed in a series of comparative papers in this issue which focus on the regulation...

  2. Caring for Participation in STS

    DEFF Research Database (Denmark)

    Nielsen, Karen Dam

    2015-01-01

    In this short report from the EASST Conference 2014, I sketch a handful of presentations that engaged with ‘participation’. Two tracks, in particular, offered interesting analyses and conceptual experiments. The first track contained primarily empirically driven studies of ‘technologies of partic......In this short report from the EASST Conference 2014, I sketch a handful of presentations that engaged with ‘participation’. Two tracks, in particular, offered interesting analyses and conceptual experiments. The first track contained primarily empirically driven studies of ‘technologies...... of participation’ in (health) care and provided illustrations of the conceptual ambiguities and empirical implications that continue to make participation a problematic, yet highly relevant and intriguing STS-topic. The second track featured presentations that more explicitly contributed new analytical tools...

  3. Vulnerable participants in health research

    DEFF Research Database (Denmark)

    Nordentoft, Helle Merete; Nanna, Kappel

    2011-01-01

    and leave both professionals and researchers in ethical and moral dilemmas. In the article we specifically focus on the methodological challenges of obtaining informed consent from drug users and terminally ill cancer patients in our PhD-research. The question is how you can illuminate the needs......Ethical guidelines for conducting research are embedded in the Helsinki declaration of 1964. We contend that these abstract and intentionally universal guidelines need to be appropriated for social and health care research in which purpose and methods often deviate from medical research....... The guidelines appear to be instrumental and over simplistic representations of the often ´messy´ realities surrounding the research process which is often guided by relational and local negotiations of ethical solutions. Vulnerable participants, for instance, challenge both professional and research ethics...

  4. Complement's participation in acquired immunity

    DEFF Research Database (Denmark)

    Nielsen, Claus Henrik; Leslie, Robert Graham Quinton

    2002-01-01

    of the B cell receptor for antigen (BCR), a complex composed of the iC3b/C3d fragment-binding complement type 2 receptor (CR2, CD21) and its signaling element CD19 and the IgG-binding receptor FcgammaRIIb (CD32). The positive or negative outcome of signaling through this triad is determined by the context...... in which antigen is seen, be it alone or in association with natural or induced antibodies and/or C3-complement fragments. The aim of this review is to describe the present status of our understanding of complement's participation in acquired immunity and the regulation of autoimmune responses....

  5. Enhancing Political Participation in Jamaica

    Directory of Open Access Journals (Sweden)

    Lloyd George Waller

    2013-04-01

    Full Text Available Youth participation through political talk appears to be shifting to the online public sphere in many parts of the world. Many attribute this shift to online social networks such as Facebook. Emerging research seem to suggest that this may be a cure for the problem of political apathy among the youth. This study explores such a possibility in Jamaica. In all, 752 youth ages 15 to 24 were surveyed to ascertain whether Facebook encourages political talk among this age cohort, and what if any are the primary factors that discourage this practice. The findings suggest that (a Facebook is an extension of offline political talk among the civically engaged and politically charged youth of Jamaica; (b Facebook does not substantively encourage political talk among the politically apathetic Jamaican youth; and (c fear of political victimization is the primary factor that discourages many Jamaican youth to engage in political talk on Facebook.

  6. Effects of an 8-weeks erythropoietin treatment on mitochondrial and Whole body fat oxidation capacity during exercise in healthy males

    DEFF Research Database (Denmark)

    Guadalupe Grau, Amelia; Plenge, Ulla; Bønding, Signe Helbo

    2015-01-01

    Abstract The present investigation was performed to elucidate if the non-erythropoietic ergogenic effect of a recombinant erythropoietin treatment results in an impact on skeletal muscle mitochondrial and whole body fatty acid oxidation capacity during exercise, myoglobin concentration and angiog......Abstract The present investigation was performed to elucidate if the non-erythropoietic ergogenic effect of a recombinant erythropoietin treatment results in an impact on skeletal muscle mitochondrial and whole body fatty acid oxidation capacity during exercise, myoglobin concentration......, pyruvate, succinate) with additional electron input from β-oxidation (octanoylcarnitine) (from 60 ± 13 to 87 ± 24 pmol · s(-1) · mg(-1) P ... of recombinant erythropoietin treatment increases mitochondrial fatty acid oxidation capacity and myoglobin concentration without any effect on whole body maximal fat oxidation....

  7. A Comparison of Increases in Volume Load Over 8 Weeks of Low-Versus High-Load Resistance Training

    OpenAIRE

    Schoenfeld; Ogborn; Contreras,, J. g.; Cappaert; Silva Ribeiro; Alvar; Vigotsky

    2016-01-01

    Background It has been hypothesized that the ability to increase volume load (VL) via a progressive increase in the magnitude of load for a given exercise within a given repetition range could enhance the adaptive response to resistance training. Objectives The purpose of this study was to compare changes in volume load (VL) over eight weeks of resistance training (RT) in high-versus low-load protocols. ...

  8. Effects of 8 Weeks of Balance or Weight Training for the Independently Living Elderly on the Outcomes of Induced Slips

    Science.gov (United States)

    Kim, Sukwon; Lockhart, Thurmon

    2010-01-01

    The study was conducted to evaluate whether the balance or weight training could alter gait characteristics of elderly contributing to a reduction in the likelihood of slip-induced falls. A total of 18 elderly were evaluated for the study. The results indicated decreases in heel contact velocities and the friction demand characteristics after 8…

  9. Effects of 8 Weeks of Balance or Weight Training for the Independently Living Elderly on the Outcomes of Induced Slips

    Science.gov (United States)

    Kim, Sukwon; Lockhart, Thurmon

    2010-01-01

    The study was conducted to evaluate whether the balance or weight training could alter gait characteristics of elderly contributing to a reduction in the likelihood of slip-induced falls. A total of 18 elderly were evaluated for the study. The results indicated decreases in heel contact velocities and the friction demand characteristics after 8…

  10. Feasibility of an 8-week African American Web-based Pilot Program Promoting Healthy Eating Behaviors: Family Eats

    Science.gov (United States)

    To assess log-on rates and change in mediating variables achieved from a web-based nutrition intervention for African American families, a parent and 9- to 12-year-old daughter (n=67 families) completed questionnaires measuring dietary change mediating variables. Overall log-on rate was 59%. Signifi...

  11. EFFECTS OF 8 WEEKS OF AQUATIC AND LAND PLYOMETRIC TRAINING ON PHYSICAL PERFORMANCE IN YOUNG BASKETBALL PLAYERS

    OpenAIRE

    Hamid Arazi; Abbas Asadi

    2011-01-01

    The purpose of this study was to compare the effect of eight weeks of aquatic and landplyometric training on strength; sprint; power and agility Eighteen young male basketballplayers (height=179.34±6.11 cm; body mass= 67.80±9.52 kg; age=18.81±1.46 years; sportexperience=4.8 ±2.47 years) volunteered in this study and divided to three groups; aquaticplyometric training (APT); land plyometric training (LPT) and control group (CON).Experimental groups trained eight weeks and 3 times a week and 40...

  12. Isoleucine and valine supplementation of crude protein-reduced diets for pigs aged 5-8 weeks

    DEFF Research Database (Denmark)

    Nørgaard, Jan Værum; Fernández, José Adalberto

    2009-01-01

    The present experiment had two purposes: (i) to study crystalline amino acid supplementation to crude protein-reduced diets, and (ii) to study the effect of different isoleucine (Ile) to lysine (Lys) and valine (Val) to Lys ratios in diets for young pigs. A total of 145 pigs were weaned at 28 days...... and fed one of 5 diets for a total of 4 weeks. Two basal diets were formulated to provide crude protein in levels either as recommended (positive reference diet, PRD), or below recommendations (negative reference diet, NRD). The basal diets contained 95% of recommended Lys, and all other essential amino...... acids were provided proportionally to Lys. The NRD diet contained 0.53 Ile and 0.61 Val relative to Lys. This diet was supplemented with either Ile (0.61 of Lys) or Val (0.72 of Lys), or both Ile and Val, in order to make up the 5 diets. Supplementation with Ile to the NRD diet did not improve (P>0...

  13. Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: testing the "adipose tissue expandability" hypothesis

    National Research Council Canada - National Science Library

    Johannsen, Darcy L; Tchoukalova, Yourka; Tam, Charmaine S; Covington, Jeffrey D; Xie, Wenting; Schwarz, Jean-Marc; Bajpeyi, Sudip; Ravussin, Eric

    2014-01-01

    The presence of large subcutaneous adipocytes in obesity has been proposed to be linked with insulin resistance and type 2 diabetes through the "adipose tissue expandability" hypothesis, which holds...

  14. Response of Critical Speed to Different Macrocycle Phases during Linear Periodization on Young Swimmers

    Directory of Open Access Journals (Sweden)

    João Bartholomeu NETO

    2016-03-01

    Full Text Available Sport training programs to young swimmers have to aggregate different physical stimulus to collaborate with overall physical development, which can lead to reach best results in competitions. Linear periodization seems to be a powerful tool that allow the organization of these stimulus. However, this model has been not studied. Regarding physical capacities, aerobic fitness is inversely related with fatigue and exercise performance. Although aerobic capacity evaluation used to be expensive, critical speed (CS is easy and non - expensive tool capable to make this measurement. Thus, the aim of this study was evaluate the effects of linear periodization in CS on well - trained young swimmers. Sixteen athletes (age: 14.06  1.22 years, height: 163.52  10.99 cm, weight: 57.4  12.7 kg, body mass index: 21.24  37; 7 ♀, were underwent to a linear macrocycle training with 23 weeks divided in four mesocycles: general endurance (i.e., 4 weeks, specific endurance (i.e., 8 weeks, competitive (i.e., 7 weeks and taper (i.e., 4 weeks. Results showed significantly improve on CS after competitive and taper mesocycle phases, which was composed by higher training intensity in comparison with other macrocycle phases. Therefore, the results of the present study indicate a collaboration of mesocycle intensity on the cumulative effects of linear periodization in CS improve on young swimmers.

  15. Latino Periodicals: A Selection Guide.

    Science.gov (United States)

    Guerena, Salvador, Ed.; Pisano, Vivian M., Ed.

    This guide is a collection development tool of national scope for librarians who need in-depth coverage of Latino periodicals suitable for public, school, and academic libraries. Periodicals evaluated include general interest and popular magazines and newspapers that appeal to Spanish-speaking, bilingual, and English-speaking library patrons and…

  16. Financial Participation of Employees in Estonia

    DEFF Research Database (Denmark)

    Eamets, Raul; Mygind, Niels; Spitsa, Natalia

    2006-01-01

    Presently, legal regulation of participation of employees - financial participation as well as participation in decision-making - is not well developed in Estonia. On the one hand, it is due to the fact that no tradition of employee participation could have been formed after Estonia became...

  17. The citizens in E-participation

    DEFF Research Database (Denmark)

    Hansen, Henning Sten; Reinau, Kristian Hegner

    2006-01-01

    Recent advances in GIS and the Internet have improved the technical possibilities for supporting the public participation through e-Participation systems - e.g. Public Participation GIS. On the other hand there has been too much focus on many technical aspects of public participation with reduced...

  18. Measuring participation outcomes in rehabilitation medicine

    NARCIS (Netherlands)

    van der Zee, C.H.

    2013-01-01

    We developed the Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation) to fulfill the need for a generic measurement instrument to assess outcomes of outpatient rehabilitation programmes. The USER-Participation assesses three aspects of participation, thereby measuring bo

  19. An Exercise Prescription Intervention Program with Periodic Ergometric Grading

    Science.gov (United States)

    Owen, C. A.; Beard, E. F.

    1970-01-01

    A long term exercise prescription type of physical conditioning program has been available to executive personnel of the NASA Manned Spacecraft Center for the past two years. Periodic ergometric testing with a heart rate controlled, automatically programmed, bicycle ergometer is used to follow the individual's progress and appropriately alter his exercise prescription from time to time. Such a program appears feasible, and acceptance is excellent, dropout rates small and periodic testing participation good. Subjects training diligently can maintain satisfactory levels of conditioning.

  20. Enabling Participation In Exoplanet Science

    Science.gov (United States)

    Taylor, Stuart F.

    2015-08-01

    Determining the distribution of exoplanets has required the contributions of a community of astronomers, who all require the support of colleagues to finish their projects in a manner to enable them to enter new collaborations to continue to contribute to understanding exoplanet science.The contributions of each member of the astronomy community are to be encouraged and must never be intentionally obstructed.We present a member’s long pursuit to be a contributing part of the exoplanet community through doing transit photometry as a means of commissioning the telescopes for a new observatory, followed by pursuit of interpreting the distributions in exoplanet parameter data.We present how the photometry projects have been presented as successful by the others who have claimed to have completed them, but how by requiring its employees to present results while omitting one member has been obstructive against members working together and has prevented the results from being published in what can genuinely be called a peer-reviewed fashion.We present how by tolerating one group to obstruct one member from finishing participation and then falsely denying credit is counterproductive to doing science.We show how expecting one member to attempt to go around an ostracizing group by starting something different is destructive to the entire profession. We repeat previously published appeals to help ostracized members to “go around the observatory” by calling for discussion on how the community must act to reverse cases of shunning, bullying, and other abuses. Without better recourse and support from the community, actions that do not meet standard good collegial behavior end up forcing good members from the community. The most important actions are to enable an ostracized member to have recourse to participating in group papers by either working through other authors or through the journal. All journals and authors must expect that no co-author is keeping out a major

  1. Optical Periodicity Analysis of 3C 446 using Period04

    Indian Academy of Sciences (India)

    Fei Guo; Hao Jing Zhang

    2014-09-01

    All the data of the blazar 3C446 at 8, 4.8, 14 and 22 GHz, presented in publications from 1977 to 2006, have been compiled to generate light curves. The light curves show violent activity of 3C446. Using Period04 analysis method, we have found that there is a period of 7.2 yr, which is consistent with the results that we found using wavelet analysis method. We get the instability region as = 123.83.

  2. Challenges of Deliberation and Participation

    Directory of Open Access Journals (Sweden)

    John Forester

    2006-12-01

    Full Text Available The future of sustainability is tied to the future of our ability to manage interconnectedness and interdependence, and thus to our abilities to engage in cooperative, value-creating public deliberations and negotiations. To understand these issues, we need a better understanding of the micro-politics of planning and public participation,the relationships between our received theories and our practices, and in particular, the work of public dispute resolution and its implications for democratic deliberation and governance. We need better to understand the differences between dialogue, debate, and negotiation, as well as the corresponding work of facilitating a dialogue, moderating a debate, and mediating an actual negotiation. Contrasting processes and practical attitudes of dialogue, debate, and negotiation can teach us, in the context of creating a sustainable future, that we must devise discursive and conversational political processes and institutions that explore possible commitments so that we not only know the right things to do but actually bring ourselves and one another to do those right things.

  3. Origins Space Telescope: Community Participation

    Science.gov (United States)

    Carey, Sean J.; Origins Space Telescope Study Team

    2017-01-01

    The Origins Space Telescope (OST) is the mission concept for the Far-Infrared Surveyor, a study in development by NASA in preparation for the 2020 Astronomy and Astrophysics Decadal Survey. Origins is planned to be a large aperture, actively-cooled telescope covering a wide span of the mid- to far-infrared spectrum. Its imagers and spectrographs will enable a variety of surveys of the sky that will discover and characterize the most distant galaxies, Milky-Way, exoplanets, and the outer reaches of our Solar system. Origins will enable flagship-quality general observing programs led by the astronomical community in the 2030s. This poster will outline the ways in which the astronomical community can participate in the STDT activities and a summary of tools that are currently available or are planned for the community during the study. The Science and Technology Definition Team (STDT) would like to hear your science needs and ideas for this mission. The team can be contacted at firsurveyor_info@lists.ipac.caltech.edu.

  4. Effect of Moderate Exercise on Serum Interferon-Gamma and Interleukin-17 Levels in the Morphine Withdrawal Period

    Directory of Open Access Journals (Sweden)

    Heidarianpour

    2016-02-01

    Full Text Available Background Drug addiction triggers the infliction of a variety of diseases. Various subjects have indicated that during the withdrawal syndrome period, the immune system is weakened. Objectives This study aimed to investigate the changes in serum levels of interferon-gamma (IFN-γ and interleukin-17 (IL-17 during the morphine withdrawal syndrome induced by 8 weeks of moderate exercise and their effects on the immune system function. Materials and Methods Twenty-four male Wistar rats (220 ± 10 g were divided into four groups (n = 6: healthy control (HC, addicted control (AC, healthy trained (HT, and addicted trained (AT groups. AC and AT groups were made addicted to morphine sulfate (0.4 mg/mL in 21 days. To ensure their dependence on morphine, naloxone (3 mg/kg, i.p. was injected into the body of a number of the rats. HT and AT groups were made to run on a treadmill 5 days per week for 8 weeks while time and speed gradually increased. Both prior to the exercises and 24 hours after the last training session, blood samples were collected from all the animals, and serum IFN-γ and IL-17 serum levels were measured using the ELISA method. This research was performed at the Bu-Ali Sina University, Hamadan, Iran. Results After 8 weeks of exercise, a significant increase was observed in the serum IFN-γ level in the HT group (251.17 ± 13.045 in comparison with the HC group (234 ± 12.884 (P = 0.045. Furthermore, the serum IFN-γ level in the AT group (218.33 ± 5.164 in comparison to the AC group (190.67 ± 8.477 showed a significant increase (P = 0.000. In addition, the serum level of IFN-γ in the HT group showed a significant increase compared to the AT group (P = 0.000. After 8 weeks of exercise, there was a significant decrease in the serum IL-17 level in the HT group (22.67 ± 4.46 compared with the HC group (38.17 ± 7.68 (P = 0.005. In addition, a significant decrease was observed in serum IL-17 in the AT group (42.17 ± 7.41 in comparison

  5. Positive reinforcement training facilitates the voluntary participation of laboratory macaws with veterinary procedures.

    Science.gov (United States)

    Daugette, Kelsey F; Hoppes, Sharman; Tizard, Ian; Brightsmith, Donald

    2012-12-01

    Psittacine birds are challenging laboratory subjects, as they are typically long-lived, very social, highly intelligent, and easily stressed. The benefits of positive reinforcement techniques in animal management have been well documented for mammalian species; however, there are few publications on such programs for birds. To demonstrate the practicality of positive reinforcement training of laboratory birds to cooperate with research procedures involving direct manipulation of individuals, 9 adult macaws (Ara species; 5 individuals and 2 pairs) were trained in 10-minute sessions, twice a day for 8 weeks. The trained behaviors were: target, stay, accept liquids from a syringe, step onto a perch, step onto a scale, allow pressing a syringe to the pectoral area (surrogate for an intramuscular injection), and step onto a towel. All individually housed birds reliably targeted, stayed, and accepted a syringe, and 4 of the 5 stepped onto a perch. One bird performed all of the behaviors. Paired birds learned advanced techniques significantly faster when trained by 2 trainers versus 1 trainer. All behaviors that were mastered during the initial phase of training were successfully transferred so that the birds would reliably perform for the husbandry staff. We conclude that positive reinforcement techniques provide an effective, practical way to train laboratory macaws in behaviors useful for veterinary practice and research. Positive reinforcement used to evoke voluntary participation in procedures will help reduce stress associated with capture and restraint and improve welfare for laboratory parrots.

  6. Retinopathy of prematurity: review of a seven-year period in a Danish neonatal intensive care unit

    DEFF Research Database (Denmark)

    Arrøe, M; Peitersen, Birgit

    1994-01-01

    of the hospital. One hundred and eighty survived to at least 8 weeks of age and 170 had eye examinations. Forty-five of the 170 infants examined (26.5%) had retinopathy of prematurity (ROP) and 18 (40%) of these developed blindness or severely impaired vision, a higher incidence than reported in other studies....... Significant differences were found between infants with and without ROP for: birth weight, gestational age, Apgar score at 1 min, resuscitation, ventilator treatment, duration of supplementary oxygen, severe complications in the neonatal period and sequels from the central nervous system. Statistical analysis......, corrected for correlations, showed that the occurrence of ROP was related significantly to early intubation, hypotension, persistent ductus arteriosus and necrotizing enterocolitis....

  7. The Periodic Table in Croatia

    Directory of Open Access Journals (Sweden)

    Raos, N.

    2011-12-01

    Full Text Available The Croatian (Yugoslav Academy of Sciences and Arts was the first academy to elect D. I. Mendeleev as its honorary member (1882, whereas the periodic table of the elements has been taught regularly at the Zagreb University since 1888. The early interest of Croatian chemists in the periodic table should be attributed primarily to their pan-Slavic attitude, particularly as proof that Slavic people were able to produce "their own Newtons" (M. V. Lomonosov and D. I. Mendeleev. Such enthusiastic views, however, did not help in analyzing the contribution of Mendeleev and other scientists to the discovery and development of the periodic table of the elements.

  8. Periodic insolation variations on Mars.

    Science.gov (United States)

    Murray, B C; Ward, W R; Yeung, S C

    1973-05-11

    Previously unrecognized insolation variations on Mars are a consequence of periodic variations in eccentricity, first established by the theory of Brouwer and Van Woerkom (1950). Such annual insolation variations, characterized by both 95,000-year and 2,000,000-year periodicities, may actually be recorded in newly discovered layered deposits in the polar regions of Mars. An additional north-south variation in seasonal insolation, but not average annual insolation, exists with 51,000-year and 2,000,000-year periodicities.

  9. The window period of NEUROGENIN3 during human gestation

    NARCIS (Netherlands)

    R.J. Salisbury (Rachel J.); J. Blaylock (Jennifer); A.A. Berry (Andrew A.); R.E. Jennings (Rachel E.); R.R. de Krijger (Ronald); K.P. Hanley (Karen Piper); N.A. Hanley (Neil A)

    2014-01-01

    textabstractThe basic helix-loop-helix transcription factor, NEUROG3, is critical in causing endocrine commitment from a progenitor cell population in the developing pancreas. In human, NEUROG3 has been detected from 8 weeks postconception (wpc). However, the profile of its production and when it ce

  10. NETS - Danish participation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Alsen, S. (Grontmij - Carl Bro, Glostrup (Denmark)); Theel, C. (Baltic Sea Solutions, Holeby (Denmark))

    2008-12-15

    Within the NICe-funded project 'Nordic Environmental Technology Solutions (NETS)' a new type of networking at the Nordic level was organized in order to jointly exploit the rapidly growing market potential in the environmental technology sector. The project aimed at increased and professionalized commercialization of Nordic Cleantech in energy and water business segments through 1) closer cooperation and joint marketing activities, 2) a website, 3) cleantech product information via brochures and publications 4) and participating in relevant trade fairs and other industry events. Facilitating business-to-business activities was another core task for the NETS project partners from Norway, Sweden, Finland and Denmark with the aim to encourage total solutions for combined Cleantech system offers. The project has achieved to establish a Cleantech register of 600 Nordic Cleantech companies, a network of 86 member enterprises, produced several publications and brochures for direct technology promotion and a website for direct access to company profiles and contact data. The project partners have attended 14 relevant international Cleantech trade fairs and conferences and facilitated business-to-business contacts added by capacity building offers through two company workshops. The future challenge for the project partners and Nordic Cleantech will be to coordinate the numerous efforts within the Nordic countries in order to reach concerted action and binding of member companies for reliable services, an improved visibility and knowledge exchange. With Cleantech's growing market influence and public awareness, the need to develop total solutions is increasing likewise. Marketing efforts should be encouraged cross-sectional and cross-border among the various levels of involved actors from both the public and the private sector. (au)

  11. 75 FR 1301 - Periodic Reporting

    Science.gov (United States)

    2010-01-11

    ... From the Federal Register Online via the Government Publishing Office POSTAL REGULATORY COMMISSION 39 CFR Part 3050 Periodic Reporting AGENCY: Postal Regulatory Commission. ACTION: Proposed rule; notice of availability of rulemaking petition. SUMMARY: The Postal Service has proposed adjustments to...

  12. Autism: a "critical period" disorder?

    Science.gov (United States)

    LeBlanc, Jocelyn J; Fagiolini, Michela

    2011-01-01

    Cortical circuits in the brain are refined by experience during critical periods early in postnatal life. Critical periods are regulated by the balance of excitatory and inhibitory (E/I) neurotransmission in the brain during development. There is now increasing evidence of E/I imbalance in autism, a complex genetic neurodevelopmental disorder diagnosed by abnormal socialization, impaired communication, and repetitive behaviors or restricted interests. The underlying cause is still largely unknown and there is no fully effective treatment or cure. We propose that alteration of the expression and/or timing of critical period circuit refinement in primary sensory brain areas may significantly contribute to autistic phenotypes, including cognitive and behavioral impairments. Dissection of the cellular and molecular mechanisms governing well-established critical periods represents a powerful tool to identify new potential therapeutic targets to restore normal plasticity and function in affected neuronal circuits.

  13. Periodicities in photospheric magnetic flux

    Institute of Scientific and Technical Information of China (English)

    SONG; Wenbin; WANG; Jingxiu

    2006-01-01

    Magnetic field plays an important role in solar structure and activity. In principle, the determination of magnetic flux would provide the best general-purpose index of solar activity. Currently, the periodicity studies corresponding to photospheric magnetic flux (PMF) are very few possibly due to the absence of a uniform flux sequence. In this paper, by using 383 NSO/Kitt Peak magnetic synoptic charts we reconstruct a flux sequence from February 1975 to August 2003 and perform a relatively systemic periodicity analysis with two methods of the Scargle periodogram and the Morlet wavelet transform. As a result, four periods are found at around 1050, 500, 300 and 160 days. We analyze these periods' temporal variabilities in detail and discuss their respective origins briefly.

  14. Romania as Participant in the Globalization Process

    Directory of Open Access Journals (Sweden)

    Sergiu-Lucian Sorcaru

    2016-08-01

    Full Text Available The objective of the paper is to present the EU policies, how they relate with Member States and with its partners, the multiculturalism has never been an impediment, but it has made it special, mentioning here the economic level, where the Union has the highest GDP per capita in the world. Our intention is to present the components of globalization, a phenomenon that is the basis for the European Union and the sudden evolution of Romania in the recent years. Romania was integrated in the globalization process and took advantage of all the benefits of this engine of the modern world. The result lies in a better understanding of EU policies and its effects on the Romanian economy. In this paper we have achieved an analysis of non-refundable grants offered by the European Union for the period 2007-20013 and how they helped the industrial and social development of Romania. The added value of the scientific interpretation of the Romanian situation at economic level is highlighted by the beneficial influence of the European space, opening towards a global market and the original approach in economic terms of the development analysis and participation in the globalization process.

  15. Period Integrals and Tautological Systems

    CERN Document Server

    Lian, Bong H; Yau, Shing-Tung

    2011-01-01

    We study period integrals of CY hypersurfaces in a partial flag variety. We construct a holonomic system of differential equations which govern the period integrals. By means of representation theory, a set of generators of the system can be described explicitly. The results are also generalized to CY complete intersections. The construction of these new systems of differential equations have lead us to the notion of a tautological system.

  16. Period-doubling cascades galore

    OpenAIRE

    Sander, Evelyn; Yorke, James A.

    2009-01-01

    The appearance of numerous period-doubling cascades is among the most prominent features of {\\bf parametrized maps}, that is, smooth one-parameter families of maps $F:R \\times {\\mathfrak M} \\to {\\mathfrak M}$, where ${\\mathfrak M}$ is a smooth locally compact manifold without boundary, typically $R^N$. Each cascade has infinitely many period-doubling bifurcations, and it is typical to observe -- such as in all the examples we investigate here -- that whenever there are any cascades, there are...

  17. Periodic billiard trajectories in polyhedra

    CERN Document Server

    Bedaride, Nicolas

    2011-01-01

    We consider the billiard map inside a polyhedron. We give a condition for the stability of the periodic trajectories. We apply this result to the case of the tetrahedron. We deduce the existence of an open set of tetrahedra which have a periodic orbit of length four (generalization of Fagnano's orbit for triangles), moreover we can study completly the orbit of points along this coding.

  18. Jupiter and Saturn Rotation Periods

    CERN Document Server

    Helled, Ravit; Anderson, John D

    2009-01-01

    Anderson & Schubert (2007, Science,317,1384) proposed that Saturn's rotation period can be ascertained by minimizing the dynamic heights of the 100 mbar isosurface with respect to the geoid; they derived a rotation period of 10h 32m 35s. We investigate the same approach for Jupiter to see if the Jovian rotation period is predicted by minimizing the dynamical heights of its isobaric (1 bar pressure level) surface using zonal wind data. A rotation period of 9h 54m 29s is found. Further, we investigate the minimization method by fitting Pioneer and Voyager occultation radii for both Jupiter and Saturn. Rotation periods of 9h 55m 30s and 10h 32m 35s are found to minimize the dynamical heights for Jupiter and Saturn, respectively. Though there is no dynamical principle requiring the minimization of the dynamical heights of an isobaric surface, the successful application of the method to Jupiter lends support to its relevance for Saturn. We derive Jupiter and Saturn rotation periods using equilibrium theory in ...

  19. Sequence periodic pattern of HERV LTRs: A matrix simulation algorithm

    Indian Academy of Sciences (India)

    Shihua Zhang; Jing Xu; Chaoling Wei

    2012-03-01

    Flanking regulatory long terminal repeats (LTRs) in Human endogenous retrovirus (HERV) is a kind of typical DNA repeat that is widespread in the human genome. Currently, many algorithms have been developed to detect the latent periodicity of a wide range of DNA repeats. However, no such attempt was made for HERV LTRs. The present study focused on the investigation of the possible sequence periodic patterns in the HERV LTRs and their regulatory mechanisms. We calculated the sequence periods of 5′, 3′ and combined LTRs in HERVs with our devised matrix simulation algorithm. It is interesting that 5′ and 3′ LTRs have the same period of 7, and combined LTRs have a period of 9. These results indicated that HERV LTRs have predominant periodic patterns. Based on the obtained sequence periodicity, we constructed periodic consensus sequences of 5′, 3′ and combined LTRs. As to 5′ and 3′ LTRs with the same period – 7, we manually scanned the nucleotide bases in the corresponding positions of their periodic consensus sequences, and found some positions have the nucleotide base unchanged, such as the 1st, 5th and 7th positions. These conservative nucleotide base positions represent critical binding sites of regulatory LTRs, and may be indicative of conserved regulatory mechanisms in LRT-participating regulatory networks.

  20. Consumer food system participation: a community analysis.

    Science.gov (United States)

    Griffin, Mary K; Sobal, Jeffery

    2014-01-01

    This study examined the prevalence, patterns, and health associations of consumer participation in different stages of the food system using a survey of 663 adults in one U.S. county. Consumer food system participation by stage was 43% in food production, 47% in food processing, 65% in food distribution, 62% in food acquisition, 61% in food preparation, and 100% in food consumption. Consumers participated in an average of 3.7 of these 6 possible stages. Women and unmarried people participated in more stages. Food system participation was associated with few health problems, although people reporting some illnesses had higher food system participation.

  1. Efficiency of dairy farms participating and not participating in veterinary herd health management programs.

    Science.gov (United States)

    Derks, Marjolein; Hogeveen, Henk; Kooistra, Sake R; van Werven, Tine; Tauer, Loren W

    2014-12-01

    This paper compares farm efficiencies between dairies who were participating in a veterinary herd health management (VHHM) program with dairies not participating in such a program, to determine whether participation has an association with farm efficiency. In 2011, 572 dairy farmers received a questionnaire concerning the participation and execution of a VHHM program on their farms. Data from the questionnaire were combined with farm accountancy data from 2008 through 2012 from farms that used calendar year accounting periods, and were analyzed using Stochastic Frontier Analysis (SFA). Two separate models were specified: model 1 was the basic stochastic frontier model (output: total revenue; input: feed costs, land costs, cattle costs, non-operational costs), without explanatory variables embedded into the efficiency component of the error term. Model 2 was an expansion of model 1 which included explanatory variables (number of FTE; total kg milk delivered; price of concentrate; milk per hectare; cows per FTE; nutritional yield per hectare) inserted into the efficiency component of the joint error term. Both models were estimated with the financial parameters expressed per 100 kg fat and protein corrected milk and per cow. Land costs, cattle costs, feed costs and non-operational costs were statistically significant and positive in all models (P<0.01). Frequency distributions of the efficiency scores for the VHHM dairies and the non-VHHM dairies were plotted in a kernel density plot, and differences were tested using the Kolmogorov-Smirnov two-sample test. VHHM dairies had higher total revenue per cow, but not per 100 kg milk. For all SFA models, the difference in distribution was not statistically different between VHHM dairies and non-VHHM dairies (P values 0.94, 0.35, 0.95 and 0.89 for the basic and complete model per 100 kg fat and protein corrected milk and per cow respectively). Therefore we conclude that with our data farm participation in VHHM is not related

  2. Periodic pattern detection in sparse boolean sequences

    Directory of Open Access Journals (Sweden)

    Hérisson Joan

    2010-09-01

    Full Text Available Abstract Background The specific position of functionally related genes along the DNA has been shown to reflect the interplay between chromosome structure and genetic regulation. By investigating the statistical properties of the distances separating such genes, several studies have highlighted various periodic trends. In many cases, however, groups built up from co-functional or co-regulated genes are small and contain wrong information (data contamination so that the statistics is poorly exploitable. In addition, gene positions are not expected to satisfy a perfectly ordered pattern along the DNA. Within this scope, we present an algorithm that aims to highlight periodic patterns in sparse boolean sequences, i.e. sequences of the type 010011011010... where the ratio of the number of 1's (denoting here the transcription start of a gene to 0's is small. Results The algorithm is particularly robust with respect to strong signal distortions such as the addition of 1's at arbitrary positions (contaminated data, the deletion of existing 1's in the sequence (missing data and the presence of disorder in the position of the 1's (noise. This robustness property stems from an appropriate exploitation of the remarkable alignment properties of periodic points in solenoidal coordinates. Conclusions The efficiency of the algorithm is demonstrated in situations where standard Fourier-based spectral methods are poorly adapted. We also show how the proposed framework allows to identify the 1's that participate in the periodic trends, i.e. how the framework allows to allocate a positional score to genes, in the same spirit of the sequence score. The software is available for public use at http://www.issb.genopole.fr/MEGA/Softwares/iSSB_SolenoidalApplication.zip.

  3. Physical Activity in High School during "Free-Time" Periods

    Science.gov (United States)

    Silva, Pedro; Sousa, Michael; Sá, Carla; Ribeiro, José; Mota, Jorge

    2015-01-01

    The purpose of this study was to examine youth physical activity (PA) in free-time periods during high school days and their contribution to total PA. Differences in terms of sex, age, body mass index and school level were assessed in a sample of Portuguese adolescents. Participants totalled 213 (135 girls), aged 14.6 ± 1.7, from two different…

  4. 42 CFR 460.190 - Monitoring during trial period.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Monitoring during trial period. 460.190 Section 460.190 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES.... (v) Observation of program operations, including marketing, participant services, enrollment...

  5. Lipid mobilisation and oxidative stress as metabolic adaptation processes in dairy heifers during transition period.

    Science.gov (United States)

    Turk, R; Podpečan, O; Mrkun, J; Kosec, M; Flegar-Meštrić, Z; Perkov, S; Starič, J; Robić, M; Belić, M; Zrimšek, P

    2013-10-01

    The objective of this study was to evaluate metabolic disorders and oxidative stress in dairy heifers during the transition period. Possible relationships between lipid mobilisation indicators and oxidative stress markers were investigated as well. Nineteen dairy heifers were included in the study. Blood samples were collected at the time of estrus synchronisation in heifers, at insemination, three weeks after insemination, one week before calving, at calving and 1, 2, 4 and 8 weeks postpartum. Common metabolic parameters, beta-hydroxybutyrate (BHB), free fatty acids (FFA), paraoxonase-1 (PON1) activity and total antioxidative status (TAS) were analysed. Around insemination, no significant difference was observed in the majority of tested parameters (P>0.05). However, the transition period markedly affected the concentration of triglycerides, total cholesterol, HDL-C, BHB, FFA, TAS and PON1activity. Positive correlations between PON1 activity and total cholesterol, HDL-C and triglycerides were noted but inverse correlations with FFA, BHB and bilirubin were found indicating that PON1 activity changed with lipid metabolism and was influenced by negative energy balance. These findings suggest that lipid mobilisation and oxidative stress are part of a complex metabolic adaptation to low energy balance which reaches equilibrium later in advanced lactation.

  6. Assessing in-class participation for EFL: considerations of effectiveness and fairness for different learning styles

    National Research Council Canada - National Science Library

    Crosthwaite, Peter R; Bailey, Daniel R; Meeker, Ashley

    2015-01-01

    ... styles.The level of participation was measured across ten criteria over a one-semester period in four classes of beginner/intermediate level adult Korean students of English as a foreign language (EFL...

  7. Determinants of participation in further training among workers with disabilities.

    Science.gov (United States)

    Pagán, Ricardo

    2015-01-01

    To analyse the determinants of the participation in further training for workers without and with disabilities in Germany. In particular, we are interested in testing the hypothesis that people with disabilities are less likely to receive further training. Using longitudinal data from the German Socio-Economic Panel which covers the period 1989 to 2008, we estimate panel data regression models that allow us to identify the factors affecting the likelihood to participate in further training for people without and with disabilities. The results confirm that workers with disabilities are less likely to participate in further training as compared to workers without disabilities (especially among males). In addition, variables such as age, years of education, occupation and firm size have a significant effect on the likelihood to get involved in further training for the disabled sample. We also found that people with disabilities have experienced more intensely the changes and variations in the participation rates over the period analysed compared to people without disabilities. From a public policy perspective, these findings show the importance of designing and implementing specific training programs for people with disabilities, which can contribute to maintaining and increasing their integration in the German labour market. Training and vocational rehabilitation can in many cases be critical to achieve or secure employment. A person becoming disabled may, even after completion of the medical rehabilitation process, not be able to continue to work in the previous occupation. Rehabilitation specialists must be more involved within the design, provision and implementation of further training. They can also help to identify adaptive equipment and specific training tools that contribute to increasing the participation in further training among the disabled population. However, the odds of participating in further training among workers with disabilities is around 17

  8. Structural Estimation of Stock Market Participation Costs

    DEFF Research Database (Denmark)

    Khorunzhina, Natalia

    2013-01-01

    This paper develops and estimates a dynamic model of stock market participation, where consumers' decisions regarding stock market participation are influenced by participation costs. The practical significance of the participation costs is considered as being a channel through which financial...... education programs can affect consumers' investment decisions. Using household data from the Panel Study of Income Dynamics, I estimate the magnitude of the participation cost, allowing for individual heterogeneity in it. The results show the average stock market participation cost is about 4–6% of labor...... income; however, it varies substantially over consumers' life. The model successfully predicts the level of the observed participation rate and the increasing pattern of stock market participation over the consumers' life cycle....

  9. 77 FR 70176 - Previous Participation Certification

    Science.gov (United States)

    2012-11-23

    ... URBAN DEVELOPMENT Previous Participation Certification AGENCY: Office of the Chief Information Officer... digital submission of all data and certifications is available via HUD's secure Internet systems. However...: Previous Participation Certification. OMB Approval Number: 2502-0118. Form Numbers: HUD-2530 ....

  10. Periodic Sweep Coverage Scheme Based on Periodic Vehicle Routing Problem

    Directory of Open Access Journals (Sweden)

    Li Shu

    2014-03-01

    Full Text Available We provide a sweep coverage algorithm for routing mobile sensors that communicate with a central data sink. This algorithm improves on its predecessors by reducing the number of unnecessary scans when different points of interest (POIs have different requirements for the time interval within which they must be scanned (sweep period. Most sweep coverage algorithms seek to minimize the number of sensors required to cover a given collection of POIs. When POIs have different sweep period requirements, existing algorithms will produce solutions in which sensors visit some POIs much more frequently than is necessary. We define this as the POI Over-Coverage problem. In order to address this problem we develop a Periodic Sweep Coverage (PSC scheme based on a well-known solution to the Periodic Vehicle Routing Problem (PVRP. Our algorithm seeks a route for the mobile sensors that minimizes the number of unnecessary visits to each POI. To verify and test the proposed scheme we implemented a C++ simulation and ran scenarios with a variety of POI topologies (number and distribution of the POIs and the speed at which sensors could travel. The simulation results show that the PSC algorithm outperforms other sweep coverage algorithms such as CSweep and Vehicle Routing Problem Sweep Coverage (VRPSC on both the average number of sensors in a solution and in the computational time required to find a solution. Our results also demonstrate that the PSC scheme is more suitable for the sweep coverage scenarios in which higher speed mobile sensors are used.

  11. Open source innovation phenomenon, participant behaviour, impact

    CERN Document Server

    Herstatt, Cornelius

    2015-01-01

    Open Source Innovation (OSI) has gained considerable momentum within the last years. Academic and management practice interest grows as more and more end-users consider and even participate in Open Source product development like Linux, Android, or Wikipedia. Open Source Innovation: Phenomenon, Participant Behaviour, Impact brings together rigorous academic research and business importance in scrutinizing OCI from three perspectives: The Phenomenon, Participants' Behavior, and Business Implications. The first section introduces OCI artefacts, including who is participating and why, and provide

  12. Mobility-related participation and user satisfaction

    DEFF Research Database (Denmark)

    Brandt, Aase; Kreiner, Svend; Iwarsson, Susanne

    2010-01-01

    scale was good,while themobilityrelated participation scalewas not optimal in discriminating between personswith a high degree ofmobility-related participation. It was demonstrated that mobility-related participation and user satisfaction are separate, not related constructs. Conclusions. It can...... be concluded that the investigated mobility-related participation and user satisfaction constructs appear to be valid. Since the two constructs are not related and both yield important information, both dimensions should be evaluated in outcomes research and praxis targeting powered wheelchair interventions...

  13. Periodicity, the Canon and Sport

    Directory of Open Access Journals (Sweden)

    Thomas F. Scanlon

    2015-10-01

    Full Text Available The topic according to this title is admittedly a broad one, embracing two very general concepts of time and of the cultural valuation of artistic products. Both phenomena are, in the present view, largely constructed by their contemporary cultures, and given authority to a great extent from the prestige of the past. The antiquity of tradition brings with it a certain cachet. Even though there may be peripheral debates in any given society which question the specifics of periodization or canonicity, individuals generally accept the consensus designation of a sequence of historical periods and they accept a list of highly valued artistic works as canonical or authoritative. We will first examine some of the processes of periodization and of canon-formation, after which we will discuss some specific examples of how these processes have worked in the sport of two ancient cultures, namely Greece and Mesoamerica.

  14. Inflation from periodic extra dimensions

    CERN Document Server

    Higaki, Tetsutaro

    2016-01-01

    We discuss a realization of a small field inflation based on string inspired supergravities. In theories accompanying extra dimensions, compactification of them with small radii is required for realistic situations. Since the extra dimension can have a periodicity, there will appear (quasi-)periodic functions under transformations of moduli of the extra dimensions in low energy scales. Such a periodic property can lead to a UV completion of so-called multi-natural inflation model where inflaton potential consists of a sum of multiple sinusoidal functions with a decay constant smaller than the Planck scale. As an illustration, we construct a SUSY breaking model, and then show that such an inflaton potential can be generated by a sum of world sheet instantons in intersecting brane models on extra dimensions containing $T^2/{\\mathbb Z}_2$ orbifold. We show also predictions of cosmic observables by numerical analyzes.

  15. 36 CFR 801.8 - Public participation.

    Science.gov (United States)

    2010-07-01

    .... Particularly important, with respect to the UDAG program, is participation by the citizens of neighborhoods... preservation. (b) The applicant, in preparing and following its citizen participation plan called for by 24 CFR 570.456(c)(11)(i)(A), should ensure that adequate provision is made for participation by citizens...

  16. 24 CFR 570.431 - Citizen participation.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Citizen participation. 570.431... CDBG Grants in Hawaii and Insular Areas Programs § 570.431 Citizen participation. (a) General. An... comply with the citizen participation requirements described in this section, including requirements...

  17. 24 CFR 1003.604 - Citizen participation.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Citizen participation. 1003.604... Requirements § 1003.604 Citizen participation. (a) In order to permit residents of Indian tribes and Alaska.... Accordingly, the citizen participation requirements of this section do not include concurrence by any...

  18. 12 CFR 614.4330 - Loan participations.

    Science.gov (United States)

    2010-01-01

    ... borrower distress or default; (4) Provide for sharing of risk; (5) Set forth conditions for the offering and acceptance of the loan participation and termination of the agreement; (6) Provide for sharing of... Purchases and Sales § 614.4330 Loan participations. Agreements to purchase or sell a participation interest...

  19. 5 CFR 919.980 - Participant.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Participant. 919.980 Section 919.980 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 919.980 Participant. Participant means any...

  20. Evaluating Public Participation Exercises: A Research Agenda

    NARCIS (Netherlands)

    Rowe, G.; Frewer, L.J.

    2004-01-01

    Abstract The concept of public participation is one of growing interest in the UK and elsewhere, with a commensurate growth in mechanisms to enable this. The merits of participation, however, are difficult to ascertain, as there are relatively few cases in which the effectiveness of participation ex