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Sample records for 72 hour binge

  1. Change in the body temperature of healthy term infant over the first 72 hours of life

    Institute of Scientific and Technical Information of China (English)

    李萌霞; 孙革; NEUBAUERHenning

    2004-01-01

    Objective:To determine the range of body temperature in a group of healthy Chinese term neonates over the first 72 hours of life and to assess the influence of body weight, gestational age and route of delivery.Method: All 200 consecutive cases of neonates delivered at our hospital from March to August 2001 were included in this retrospective study.Temperatures were measured immediately after delivery, after 30 minutes, 1 hour, 2 hours, 8 hours and 15 hours and on the 2nd and 3rd day. Axillary temperatures ranging from 36.5℃ to 37℃ were regarded as normal. No cases of maternal fever or systemic infection of the newborns were discovered. All infants were discharged in good general condition. Results:The mean rectal temperature at birth was 37.19℃. The lowest average temperature was reached at 1 hour after delivery (36.54℃) with a significant difference between natural delivery (36.48℃) and section (36.59℃) (P<0.05).Temperature subsequently rose to 36.70℃ at 8 hours and 36.78℃ at 15 hours (P<0.05).Hypothermia was seen in 51.8% and hypothermia in 42.5% of the patients.On the 3rd day after delivery, 96% of all temperatures were in the normal range. A significant relation was found between hypothermia and both low birth weight (P<0.001) and low gestational age (P<0.05).Conclusion: The reference range presently used did not include all physiological temperatures in the first 72 hours of life. Considering other factors,such as birth weight, route of delivery,gestational age and body temperature on the 2nd and 3rd day of life, may help to correctly assess the significance of temperatures beyond the reference range.

  2. Change in the body temperature of healthy term infant over the first 72 hours of life

    Institute of Scientific and Technical Information of China (English)

    LI Meng-xia (李萌霞); SUN Ge (孙革); NEUBAUER Henning

    2004-01-01

    Objective: To determine the range of body temperature in a group of healthy Chinese term neonates over the first 72 hours of life and to assess the influence of body weight, gestational age and route of delivery. Method: All 200 consecutive cases of neonates delivered at our hospital from March to August 2001 were included in this retrospective study. Temperatures were measured immediately after delivery, after 30 minutes, 1 hour, 2 hours, 8 hours and 15 hours and on the 2nd and 3rd day. Axillary temperatures ranging from 36.5 oC to 37 oC were regarded as normal. No cases of maternal fever or systemic infection of the newborns were discovered. All infants were discharged in good general condition. Results: The mean rectal temperature at birth was 37.19 ℃. The lowest average temperature was reached at 1 hour after delivery (36.54 ℃) with a significant difference between natural delivery (36.48 ℃) and section (36.59 ℃) (P<0.05). Temperature subsequently rose to 36.70 ℃ at 8 hours and 36.78 ℃ at 15 hours (P<0.05). Hypothermia was seen in 51.8% and hypothermia in 42.5% of the patients. On the 3rd day after delivery, 96% of all temperatures were in the normal range. A significant relation was found between hypothermia and both low birth weight (P<0.001) and low gestational age (P<0.05). Conclusion: The reference range presently used did not include all physiological temperatures in the first 72 hours of life. Considering other factors, such as birth weight, route of delivery, gestational age and body temperature on the 2nd and 3rd day of life, may help to correctly assess the significance of temperatures beyond the reference range.

  3. Understanding Why Patients Return to the Emergency Department after Mild Traumatic Brain Injury within 72 Hours

    Directory of Open Access Journals (Sweden)

    Ganti, Latha

    2015-05-01

    Full Text Available Introduction: Although there are approximately 1.1 million case presentations of mild traumatic brain injury (mTBI in the emergency department (ED each year, little data is available to clinicians to identify patients who are at risk for poor outcomes, including 72-hour ED return after discharge. An understanding of patients at risk for ED return visits during the hyperacute phase following head injury would allow ED providers to develop clinical interventions that reduce its occurrence and improve outcomes. Methods: This institutional review board-approved consecutive cohort study collected injury and outcome variables on adults with the purpose of identifying positive predictors for 72-hour ED return visits in mTBI patients. Results: Of 2,787 mTBI patients, 145 (5% returned unexpectedly to the ED within 72 hours of hospital discharge. Positive predictors for ED return visits included being male (p=0.0298, being black (p=0.0456, having a lower prehospital Glasgow Coma Score (p=0.0335, suffering the injury due to a motor vehicle collision (p=0.0065, or having a bleed on head computed tomography (CT (p=0.0334. ED return visits were not significantly associated with age, fracture on head CT, or symptomology following head trauma. Patients with return visits most commonly reported post-concussion syndrome (43.1%, pain (18.7%, and recall for further clinical evaluation (14.6% as the reason for return. Of the 124 patients who returned to the ED within 72 hours, one out of five were admitted to the hospital for further care, with five requiring intensive care unit stays and four undergoing neurosurgery. Conclusion: Approximately 5% of adult patients who present to the ED for mTBI will return within 72 hours of discharge for further care. Clinicians should identify at-risk individuals during their initial visits and attempt to provide anticipatory guidance when possible. [West J Emerg Med. 2015;16(2:481–485.

  4. Characteristics of patients who made a return visit within 72 hours to the emergency department of a Singapore tertiary hospital

    Science.gov (United States)

    Chan, Amy Hui Sian; Ho, Shu Fang; Fook-Chong, Stephanie Man Chung; Lian, Sherman Wei Qiang; Liu, Nan; Ong, Marcus Eng Hock

    2016-01-01

    INTRODUCTION 72-hour emergency department (ED) reattendance is a widely-used quality indicator for quality of care and patient safety. It is generally assumed that patients who return within 72 hours of ED discharge (72-hour re-attendees) received inadequate treatment or evaluation. The current literature also suggests considerable variation in probable causes of 72-hour ED reattendances internationally. This study aimed to understand the characteristics of these patients at the ED of a Singapore tertiary hospital. METHODS We conducted a retrospective cohort study on all ED visits between 1 January 2013 and 31 December 2013. 72-hour re-attendees were compared against non-re-attendees based on patient demographics, mode of arrival, patient acuity category status (i.e. P1/P2/P3/P4), seniority ranking of doctor-in-charge and medical diagnoses. Multivariate analysis using the generalised linear model was conducted on variables associated with 72-hour ED re-attendance. RESULTS Among 104,751 unique patients, 3,065 (2.93%) were in the 72-hour re-attendees group. Multivariate analysis showed that the following risk factors were associated with higher risk of returning within 72 hours: male gender, older age, arrival by ambulance, triaged as P2, diagnoses of heart problems, abdominal pain or viral infection (all p < 0.001), and Chinese ethnicity (p = 0.006). There was no significant difference in the seniority ranking of the doctor-in-charge between both groups (p = 0.419). CONCLUSION Several patient and event factors were associated with higher risk of being a 72-hour re-attendee. This study forms the basis for hypothesis generation and further studies to explore reasons behind reattendances so that interventions can be developed to target high-risk groups. PMID:27353286

  5. DNA degradation within mouse brain and dental pulp cells 72 hours postmortem

    Institute of Scientific and Technical Information of China (English)

    Jilong Zheng; Xiaona Li; Di Shan; Han Zhang; Dawei Guan

    2012-01-01

    In this study, we sought to elucidate the process of DNA degradation in brain and dental pulp cells of mice, within postmortem 0-72 hours, by using the single cell gel electrophoresis assay and professional comet image analysis and processing techniques. The frequency of comet-like cells, the percentage of tail DNA, tail length, tail moment, Olive moment and tail area increased in tandem with increasing postmortem interval. In contrast, the head radius, the percentage of head DNA and head area showed a decreasing trend. Linear regression analysis revealed a high correlation between these parameters and the postmortem interval. The findings suggest that the single cell gel electrophoresis assay is a quick and sensitive method to detect DNA degradation in brain and dental pulp cells, providing an objective and accurate new way to estimate postmortem interval.

  6. Operational Solar Forecasting System for DNI and GHI for Horizons Covering 5 Minutes to 72 Hours

    Science.gov (United States)

    Coimbra, C. F.

    2014-12-01

    I will describe the methodology used to develop and deploy operationally a comprehensive solar forecasting system for both concentrated and non-concentrated solar technologies. This operational forecasting system ingests data from local telemetry, remote sensing and Numerical Weather Prediction (NWP) models, processes all the diferent types of data (time series, sky images, satellite images, gridded data, etc.) to produce concatenated solar forecasts from 5 minutes out to 72 hours into the future. Each forecast is optimized with stochastic learning techniques that include input selection, model topology optimization, model output statistics, metric fitness optimization and machine learning. These forecasts are used by solar generators (plant managers), utilities and independent system operators for operations, scheduling, dispatching and market participation.

  7. PREDICTION OF OUTCOME OF PAEDIATRIC PATIENTS BY VALIDATING PRISM III SCORING WITHIN 12 HOURS AND PRISM III AT 72-84 HOURS AFTER INITIATION OF THE TREATMENT

    OpenAIRE

    Sonica

    2014-01-01

    `BACKGROUND: One of the scoring systems in Pediatric Intensive Care is the PRISM III (PAEDITRIC RISK OF MORTALITY III) which is an updated version of PRISM. Study was done at time point 72 hrs of initiation of therapy as well in a view that it will better prognosticate the outcome. AIMS: 1. To find out PRISM III within 1st 12 hours of admission and at 72-84 hours of admission, 2. To evaluate any correlation between PRISM III and mortality, 4.To find out correlation between...

  8. Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

    DEFF Research Database (Denmark)

    Smith, Julie; Christoffersen, Christina; Nørgaard, Linn Maiken;

    2013-01-01

    Plasma measurement of cardiac natriuretic peptides constitutes promising markers of congenital heart disease. However, concentrations change rapidly and dramatically during the first days after delivery even in healthy neonates, which complicates clinical interpretation. It is unknown whether the......, resembling the transition from fetal to neonate circulation. However, the cardiac gene expression does not explain plasma concentrations....... 72 hours of life (from 2 litters, n = 44). Chamber-specific ANP and BNP mRNA levels reflected hemodynamic neonate changes at birth but did not correlate with circulating natriuretic peptide concentrations. However, plasma pro-ANP and creatinine concentrations were closely correlated (P < .0001; r = 0.......73). Plasma pro-ANP levels were highest on the day of delivery (5580 pmol/L [4320-6786] decreasing to 2484 pmol/L [1602-2898] after 72 hours, P < .0001). During the 72 hours, gel chromatography suggested that the translational products in circulation and in atrial tissue were immature, ie, unprocessed pro...

  9. Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells

    OpenAIRE

    Shikh Al Sook, Mohamad Khir; Gabriel, Annick; Piret, Joëlle; Waroux, Olivier; Tonus, Céline; Connan, Delphine; Antoine, Nadine; Baise, Etienne

    2015-01-01

    Background Mesenchymal stem cells (MSCs) harvested from cadaveric tissues represent a promising approach for regenerative medicine. To date, no study has investigated whether viable MSCs could survive in cadaveric tissues from tendon or ligament up to 72 hours of post-mortem. The purpose of the present work was to find out if viable MSCs could survive in cadaveric tissues from adult equine ligaments up to 72 hours of post-mortem, and to assess their ability (i) to remain in an undifferentiate...

  10. OVERTIME HOURS AND PREMIUM PAY, MAY 1965. SPECIAL LABOR FORCE REPORT NUMBER 72.

    Science.gov (United States)

    WETZEL, JAMES R.

    THE EXTENT TO WHICH PERSONS WITH WORKWEEKS OF MORE THAN 40 HOURS RECEIVE PREMIUM PAY AND THE EXTENT TO WHICH THEY REGULARLY WORK LONG HOURS WERE STUDIED. THE DATA COLLECTED EACH YEAR IN THE MAY SURVEY OF THE LABOR FORCE BY THE BUREAU OF THE CENSUS, APPLY TO WAGE AND SALARY WORKERS WITH ONE JOB WHO WORKED 41 HOURS OR MORE DURING THE SURVEY WEEK.…

  11. [Hypoglycemia in nondiabetic patients: When is the 72-hour-fast test required and how can it be interpreted?].

    Science.gov (United States)

    Vezzosi, Delphine; Bennet, Antoine; Grunenwald, Solange; Caron, Philippe

    2016-06-01

    Whereas hypoglycaemia is uncommon in nondiabetic patients, it is a frequent reason for consultation. Hypoglycaemia is confirmed when criteria of Whipple's triad are fulfilled. If a venous sample cannot be collected when hypoglycemia occurs spontaneously, a 72-hour-fast test should be performed firstly to affirm the reality of hypoglycaemia and secondly to make the etiological diagnosis. Before carrying out this long and expensive test, the obvious causes of hypoglycaemia must be ruled out: iatrogenic, severe prolonged undernutrition, liver or renal deficiency, adrenal insufficiency, IGFII or pro-IGFII secreting tumours…At the time of hypoglycemia, plasma insulin≥3mUI/L, C-peptide≥0.6ng/mL, proinsulin≥5pmol/L associated with plasma beta-hydroxybutyrate≤2700μmol/L provide evidence for inappropriate insulin secretion. The lack of hypoglycaemia after a 72-hour-fast test rules out, in the majority of cases, organic hypoglycaemia. PMID:27208915

  12. Hypoglycemia Secondary to Sulfonylurea Ingestion in a Patient with End Stage Renal Disease: Results from a 72-Hour Fast

    Directory of Open Access Journals (Sweden)

    Alice Abraham

    2015-01-01

    Full Text Available Insulin, proinsulin, and C-peptide levels increase with sulfonylurea exposure but the acuity of increase has not been described in dialysis patients. We present a case of a dialysis patient who presented with hypoglycemia and was found to have accidental sulfonylurea ingestion. This is a 73-year-old man with ESRD on peritoneal dialysis, without history of diabetes, who presented with hypoglycemia. Past medical history includes multiple myeloma, congestive heart failure, and hypertension. At initial presentation, his blood glucose was 47 mg/dL, with concomitant elevations in the following: C-peptide 30.5 (nl: 0.8–3.5 ng/mL, insulin 76 (nl: 3–19 μIU/mL, and proinsulin 83.3 (nl: ≤8.0 pmol/L. During the 72-hour fast, which he completed without hypoglycemia, insulin declined to be within normal limits (to 12 μIU/mL; proinsulin (to 12.1 pmol/L and C-peptide (to 7.2 ng/mL levels decreased but remained elevated. The sulfonylurea screen ultimately returned positive for glipizide, clinching the diagnosis. This is the first reported case which characterizes the chronic elevation of proinsulin in a patient with ESRD, as well as its dramatic increase after a presumed solitary exposure to sulfonylurea. The 72-hour fast conducted gives insight into the clearance of insulin, proinsulin, and C-peptide after sulfonylurea ingestion in ESRD.

  13. Repeated Intra-Arterial Thrombectomy within 72 Hours in a Patient with a Clear Contraindication for Intravenous Thrombolysis

    Directory of Open Access Journals (Sweden)

    Mona Laible

    2015-01-01

    Full Text Available Introduction. Treating patients with acute ischemic stroke, proximal arterial vessel occlusion, and absolute contraindication for administering intravenous recombinant tissue plasminogen activator (rtPA poses a therapeutic challenge. Intra-arterial thrombectomy constitutes an alternative treatment option. Materials and Methods. We report a case of a 57-year-old patient with concomitant gastric adenocarcinoma, who received three intra-arterial thrombectomies in 72 hours due to repeated occlusion of the left medial cerebral artery (MCA. Findings. Intra-arterial recanalization of the left medial cerebral artery was performed three times with initially good success. However, two days later, the right medial cerebral artery became occluded. Owing to the overall poor prognosis at that time and knowing the wishes of the patient, we decided not to perform another intra-arterial recanalization procedure. Conclusion. To our knowledge, this is the first case illustrating the use of repeated intra-arterial recanalization in early reocclusion of intracranial vessels.

  14. Binge Eating Disorder

    Science.gov (United States)

    ... Mental health What is binge eating disorder? What causes binge eating disorder? What are the health consequences of binge eating ... more often than men. Return to top What causes binge eating disorder? Researchers are unsure of the causes and nature ...

  15. Optimal concentration and time window for proliferation and differentiation of neural stem cells from embryonic cerebral cortex:5% oxygen preconditioning for 72 hours

    Institute of Scientific and Technical Information of China (English)

    Li-li Yuan; Ying-jun Guan; Deng-dian Ma; Hong-mei Du

    2015-01-01

    Hypoxia promotes proliferation and differentiation of neural stem cells from embryonic day 12 rat brain tissue, but the concentration and time of hypoxic preconditioning are controversial. To address this, we cultured neural stem cells isolated from embryonic day 14 rat cerebral cortex in 5% and 10% oxygenin vitro. MTT assay, neurosphere number, and immunolfuorescent staining found that 5% or 10% oxygen preconditioning for 72 hours improved neural stem cell viability and proliferation. With prolonged hypoxic duration (120 hours), the proportion of apoptotic cells increased. Thus, 5% oxygen preconditioning for 72 hours promotes neural stem cell prolif-eration and neuronal differentiation. Our ifndings indicate that the optimal concentration and duration of hypoxic preconditioning for promoting proliferation and differentiation of neural stem cells from the cerebral cortex are 5% oxygen for 72 hours.

  16. Binge Drinking

    Centers for Disease Control (CDC) Podcasts

    2010-04-13

    This podcast explores the health risks of binge drinking and discusses effective community strategies to prevent it.  Created: 4/13/2010 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/13/2010.

  17. Binge Drinking

    Centers for Disease Control (CDC) Podcasts

    2010-10-05

    This podcast is based on the October, 2010 CDC Vital Signs report which indicates that drinking too much, including binge drinking, causes more than 79,000 deaths in the U.S. each year and is the third leading preventable cause of death.  Created: 10/5/2010 by Centers for Disease Control and Prevention (CDC).   Date Released: 10/5/2010.

  18. Binge Drinking Effects on EEG in Young Adult Humans

    Directory of Open Access Journals (Sweden)

    Kelly E. Courtney

    2010-05-01

    Full Text Available Young adult (N = 96 university students who varied in their binge drinking history were assessed by electroencephalography (EEG recording during passive viewing. Groups consisted of male and female non-binge drinkers (>1 to 5/4 drinks/ounces in under two hours, low-binge drinkers (5/4–7/6 drinks/ounces in under two hours, and high-binge drinkers (≥ 10 drinks/ounces in under two hours, who had been drinking alcohol at their respective levels for an average of 3 years. The non- and low-binge drinkers exhibited less spectral power than the high-binge drinkers in the delta (0–4 Hz and fast-beta (20–35 Hz bands. Binge drinking appears to be associated with a specific pattern of brain electrical activity in young adults that may reflect the future development of alcoholism.

  19. Binge eating disorder

    Science.gov (United States)

    Eating disorder - binge eating; Eating - binge; Overeating - compulsive; Compulsive overeating ... as having close relatives who also have an eating disorder Changes in brain chemicals Depression or other emotions, ...

  20. Comparison of different extenders on the preservability of rabbit semen stored at 5°C for 72 hours

    Directory of Open Access Journals (Sweden)

    Michele Di Iorio

    2014-10-01

    Full Text Available This study was designed to compare Cortalap® extender with tris-citric acid-glucose (TCG, Lepus® and Merk III®, to assess the in vitro preservability of rabbit spermatozoa stored for 72 h at 5°C. The best extender identified in vitro was then compared with fresh semen to determine fertility and prolificacy rates in vivo. Eight semen pools were split into four subsamples and each of them was diluted to a ratio of 1:10 (volume:volume with four different extenders (Lepus®, Cortalap®, TCG and Merk III® and stored at 5°C for 72 h. Sperm motility, viability, sperm membrane and acrosome integrity were evaluated in both fresh and chilled semen at 4, 24, 48 and 72 h of storage. The results showed that Cortalap® was the best extender to preserve the quality of rabbit semen in vitro over 72 h in comparison with the other extenders (P<0.05. Then, Cortalap® was used for an artificial insemination (AI trial to be compared with fresh semen. Two groups of does (n=30 each were inseminated with fresh and chilled semen. The fertility and prolificacy rates for the does inseminated with chilled semen were significantly lower compared with those inseminated with fresh semen (P<0.05. In conclusion, although Cortalap® proved to be the best extender to preserve semen quality in vitro after 72 h at 5°C, the in vivo results showed that its use is not recommended in AI programmes.

  1. GABA-BZD Receptor Modulating Mechanism of Panax quinquefolius against 72-hours Sleep Deprivation Induced Anxiety like Behavior: Possible Roles of Oxidative Stress, Mitochondrial Dysfunction and Neuroinflammation

    Directory of Open Access Journals (Sweden)

    Priyanka eChanana

    2016-03-01

    Full Text Available ABSTRACTRationale- Panax quinquefolius (American Ginseng is known for its therapeutic potential against various neurological disorders, but its plausible mechanism of action still remains undeciphered. GABA (Gamma Amino Butyric Acid plays an important role in sleep wake cycle homeostasis. Thus there exists rationale in exploring the GABA-ergic potential of Panax quinquefolius as neuroprotective strategy in sleep deprivation induced secondary neurological problems.Objective- The present study was designed to explore the possible GABA-ergic mechanism in the neuro-protective effect of Panax quinquefolius against 72-hours sleep deprivation induced anxiety like behaviour, oxidative stress, mitochondrial dysfunction, HPA-axis activation and neuroinflammation.Materials and Methods- Male laca mice were sleep deprived for 72-hours by using Grid suspended over water method. Panax quinquefolius (American Ginseng 50, 100 and 200 mg/kg was administered alone and in combination with GABA modulators (GABA Cl- channel inhibitor, GABA-benzodiazepine receptor inhibitor and GABAA agonist for 8 days, starting five days prior to 72-hours sleep deprivation period. Various behavioural (locomotor activity, mirror chamber test, biochemical (lipid peroxidation, reduced glutathione, catalase, nitrite levels, mitochondrial complexes, neuroinflammation marker (Tumour Necrosis Factor, TNF-alpha, serum corticosterone, and histopathological sections of brains were assessed. Results- 72-hours sleep deprivation significantly impaired locomotor activity, caused anxiety-like behaviour, conditions of oxidative stress, alterations in mitochondrial enzyme complex activities, raised serum corticosterone levels, brain TNFα levels and led to neuroinflammation like signs in discrete brain areas as compared to naive group. Panax quinquefolius (100 and 200 mg/kg treatment restored the behavioural, biochemical, mitochondrial, molecular and histopathological alterations. Pre-treatment of

  2. Binge Eating Disorder

    Science.gov (United States)

    ... Events Upcoming and past meetings Follow Us Social media, RSS feeds, and more Follow Us Health Information > Health Topics > Weight Management > Binge Eating Disorder | Share External Link Disclaimer Weight Management Binge Eating ...

  3. In-hospital mortality and the Glasgow Coma Scale in the first 72 hours after traumatic brain injury Escala de Coma de Glasgow en las primeras 72 horas postrauma encefalocraneano y mortalidad hospitalaria Escala de Coma de Glasgow nas primeiras 72 horas após trauma cranioencefálico e mortalidade hospitalar

    OpenAIRE

    Cristina Helena Costanti Settervall; Regina Marcia Cardoso de Sousa; Silvia Cristina Fürbringer e Silva

    2011-01-01

    This study verifies and compares the performance of three different scores obtained in the Glasgow Coma Scale (GCS) in the first 72 hours post trauma in predicting in-hospital mortality. The studied scores included those obtained after initial care was provided at the hospital, and the worst and best scores obtained in the scale in the first 72 hours post trauma. The scale’s predictive ability was assessed by the Receiver Operator Characteristic (ROC) curve. A total of 277 victims with differ...

  4. Binge drinking in pregnancy

    DEFF Research Database (Denmark)

    Kesmodel, Ulrik Schiøler

    2001-01-01

    Independent of average alcohol intake, the effect of binge drinking on adverse pregnancy outcomes in humans is only sporadically reported, but most studies in humans have found little or no effect of binge drinking on several adverse pregnancy outcomes. In a representative sample of 371 pregnant...... Danish women, the agreement between two different measures of binge drinking during the first half of pregnancy obtained from interviews and questionnaires was assessed, and the frequency and pattern of binge drinking were described. The percentage of agreement between the methods ranged between 81......% and 86%. The proportion of women who reported binge drinking depended on the definition of pregnancy, but the proportion peaked in week 3 measured from the last menstrual period and thereafter declined to approximately 1 percent in week 7. On the basis of this 1998 study, it is suggested that most human...

  5. Binge drinking in Europe.

    Science.gov (United States)

    Farke, Walter; Anderson, Peter

    2007-01-01

    Binge drinking is a pattern of heavy drinking which is observed all over Europe. The term Binge drinking implies a lot of different meanings to different people. The most popular definition used for this term is five or more 'standard drinks' in a single occasion. Binge drinking is different from intoxication, although this kind of heavy alcohol consumption can be lead to intoxication. This condition is manifested by different signs, for example slurred speech. Binge drinking is very common among the European population. In 2006 some 80 million Europeans aged 15 plus reported this kind of alcohol consumption patterns. European surveys showed that there is an increase of binge drinking across Europe amongst young people (15-16 years) old since 1995. The consequences of binge drinking contain acute and chronic effects, which are caused by long term alcohol use. The individual risks are brain damage, suicide, sexually transmitted diseases, etc. It has also an impact on harm to others than the drinkers. This includes violence and crime, accidents, etc. Each year in the European Union 2000 homicides are related to heavy drinking. There a lot of effective measures to reduce binge drinking. Strong evidence is shown by drink-driving laws, tax, reduced access to and availability of alcohol, brief interventions such as physician advice and advertising controls. PMID:18173097

  6. Treatment of Binge Eating Disorder

    OpenAIRE

    Crow, Scott

    2014-01-01

    Binge eating disorder is a common eating disorder that recently has received increasing attention. Goals in treating binge eating disorder typically include controlling binge eating and diminishing excess body weight. A variety of treatment approaches have been used, including diet/lifestyle modification, psychotherapy, and pharmacologic treatment. Diet and lifestyle interventions are somewhat effective in diminishing the binge eating behavior and lead to modest weight loss, but the weight ef...

  7. Learning Bing maps API

    CERN Document Server

    Sinani, Artan

    2013-01-01

    This is a practical, hands-on guide with illustrative examples, which will help you explore the vast universe of Bing maps.If you are a developer who wants to learn how to exploit the numerous features of Bing Maps then this book is ideal for you. It can also be useful for more experienced developers who wish to explore other areas of the APIs. It is assumed that you have some knowledge of JavaScript, HTML, and CSS. For some chapters a working knowledge of .Net and Visual Studio is also needed.

  8. In-hospital mortality and the Glasgow Coma Scale in the first 72 hours after traumatic brain injury Escala de Coma de Glasgow en las primeras 72 horas postrauma encefalocraneano y mortalidad hospitalaria Escala de Coma de Glasgow nas primeiras 72 horas após trauma cranioencefálico e mortalidade hospitalar

    Directory of Open Access Journals (Sweden)

    Cristina Helena Costanti Settervall

    2011-12-01

    Full Text Available This study verifies and compares the performance of three different scores obtained in the Glasgow Coma Scale (GCS in the first 72 hours post trauma in predicting in-hospital mortality. The studied scores included those obtained after initial care was provided at the hospital, and the worst and best scores obtained in the scale in the first 72 hours post trauma. The scale’s predictive ability was assessed by the Receiver Operator Characteristic (ROC curve. A total of 277 victims with different severity levels of blunt traumatic brain injuries were studied. The performance of the three scores that were analyzed to predict hospital mortality was moderate (0.74 to 0.79 and the areas under the curve did not present statistically significant differences. These findings suggest that any of the three studied scores can be applied in clinical practice to estimate the outcome of victims with blunt traumatic brain injuries, taking into consideration the instrument’s moderate discriminatory power.El estudio tiene como objetivos verificar y comparar el desempeño de puntajes de la Escala de Coma de Glasgow (ECGl observados en las primeras 72 horas postrauma para predecir la mortalidad hospitalaria. Los valores analizados fueron los puntajes obtenidos después de la atención inicial intra-hospitalaria, además de los peores y mejores resultados de la escala en las primeras 72 horas postrauma. La capacidad de predicción de los puntajes de la ECGl para el Estado Vital a la Salida Hospitalaria fue evaluada, utilizando la curva Reciever Operator Characteristic. Fueron estudiadas 277 víctimas, con trauma encefalocraneano contuso de diferentes gravedades. El desempeño de los puntajes de la ECGl para el estado vital a la salida hospitalaria fue moderado (0,74 a 0,79 y las áreas bajo la curva no presentaron diferencia significativa. Los resultados sugieren que cualquiera de los tres valores de la ECGl analizados pueden ser aplicados en la práctica cl

  9. Binge eating disorder

    DEFF Research Database (Denmark)

    Schousboe, Birgitte Hartvig; Waaddegaard, Mette

    2011-01-01

    Binge eating disorder kaldes også bulimi uden opkastning eller den tredje spiseforstyrrelse. Det er en udbredt, men mindre kendt spiseforstyrrelse end anoreksi og bulimi. Patienterne er ofte overvægtige og har ikke kompenserende adfærd over for overspisningen i form af opkastning eller brug af...

  10. Cytotoxic effects in 3T3-L1 mouse and WI-38 human fibroblasts following 72 hour and 7 day exposures to commercial silica nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Stępnik, Maciej, E-mail: mstep@imp.lodz.pl [Nofer Institute of Occupational Medicine, Łódź (Poland); Arkusz, Joanna; Smok-Pieniążek, Anna [Nofer Institute of Occupational Medicine, Łódź (Poland); Bratek-Skicki, Anna; Salvati, Anna; Lynch, Iseult; Dawson, Kenneth A. [Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4 (Ireland); Gromadzińska, Jolanta [Nofer Institute of Occupational Medicine, Łódź (Poland); De Jong, Wim H. [National Institute for Public Health and the Environment, Antonie van Leeuwenhoeklaan 9 NL‐3720, Bilthoven (Netherlands); Rydzyński, Konrad [Nofer Institute of Occupational Medicine, Łódź (Poland)

    2012-08-15

    The potential toxic effects in murine (3T3-L1) and human (WI-38) fibroblast cell lines of commercially available silica nanoparticles (NPs), Ludox CL (nominal size 21 nm) and CL-X (nominal size of 30 nm) were investigated with particular attention to the effect over long exposure times (the tests were run after 72 h exposure up to 7 days). These two formulations differed in physico-chemical properties and showed different stabilities in the cell culture medium used for the experiments. Ludox CL silica NPs were found to be cytotoxic only at the higher concentrations to the WI-38 cells (WST-1 and LDH assays) but not to the 3T3-L1 cells, whereas the Ludox CL-X silica NPs, which were less stable over the 72 h exposure, were cytotoxic to both cell lines in both assays. In the clonogenic assay both silica NPs induced a concentration dependent decrease in the surviving fraction of 3T3-L1 cells, with the Ludox CL-X silica NPs being more cytotoxic. Cell cycle analysis showed a trend indicating alterations in both cell lines at different phases with both silica NPs tested. Buthionine sulfoximine (γ-glutamylcysteine synthetase inhibitor) combined with Ludox CL-X was found to induce a strong decrease in 3T3-L1 cell viability which was not observed for the WI-38 cell line. This study clearly indicates that longer exposure studies may give important insights on the impact of nanomaterials on cells. However, and especially when investigating nanoparticle effects after such long exposure, it is fundamental to include a detailed physico-chemical characterization of the nanoparticles and their dispersions over the time scale of the experiment, in order to be able to interpret eventual impacts on cells. -- Highlights: ► Ludox CL silica NPs are cytotoxic to WI-38 fibroblasts but not to 3T3-L1 fibroblasts. ► Ludox CL-X silica NPs are cytotoxic to both cell lines. ► In clonogenic assay both silica NPs induce cytotoxicity, higher for CL-X silica. ► Cell cycle analysis shows

  11. Low Intensity Laser Irradiation and Growth Factors Influence Differentiation of Adipose Derived Stem Cells into Smooth Muscle Cells in a Coculture Environment over a Period of 72 Hours

    Directory of Open Access Journals (Sweden)

    Bernard Mvula

    2014-01-01

    Full Text Available Stem cells have the ability to self-renew and differentiate into several specialised cells. Low intensity laser irradiation (LILI has been shown to have positive effects on cells including adipose derived stem cells (ADSCs. Growth factors such as retinoic acid and transforming growth factor (TGF-β1 play significant roles in the differentiation of cells. This study aimed at investigating the role of LILI and growth factors on differentiation of adipose derived stem cells cocultured with smooth muscle cells (SMCs. The study used isolated human adipose derived stem cells and smooth muscle commercial cells (SKUT-1. The cells were cocultured directly in the ratio 1 : 1 using the established methods with and without growth factors (retinoic acid and TGF-β1 and then exposed to LILI at a wavelength of 636 nm with 5 J/cm2 using a diode laser. The cellular proliferation and expression of the both cell type markers were assessed using optical density and flow cytometry at 24 h and 72 h. The study showed that LILI increased the proliferation of cocultured cells. The expression of the smooth muscle cell markers increased in the coculture groups that were exposed to LILI in the presence of growth factors while those of the ADSCs decreased.

  12. Presence of Selected Methanogens, Fibrolytic Bacteria, and Proteobacteria in the Gastrointestinal Tract of Neonatal Dairy Calves from Birth to 72 Hours.

    Directory of Open Access Journals (Sweden)

    Cesar E Guzman

    Full Text Available The microbial communities in the gastrointestinal tract of a young calf are essential for the anatomical and physiological development that permits a transition from milk to solid feed. Selected methanogens, fibrolytic bacteria, and proteobacteria were quantified in the rumen fluid and tissue, abomasum fluid, cecum fluid and tissue, and feces of Holstein bull calves on day 0 (0-20 mins after birth, day 1 (24 ± 1 h after birth, day 2 (48 ± 1 h after birth, and day 3 (72 ± 1 h after birth. Methanogens, fibrolytic bacteria, and Geobacter spp. were found to be already present from birth, indicating that microbial colonization of the gastrointestinal tract occurred before or during delivery. The abundance of methanogens and Geobacter spp. differed between the days tested and between compartments of the digestive tract and feces, but such difference was not observed for fibrolytic bacteria. Our findings suggests that methanogens might have an alternative hydrogen provider such as Geobacter spp. during these early stages of postnatal development. In addition, fibrolytic bacteria were present in the rumen well before the availability of fibrous substrates, suggesting that they might use nutrients other than cellulose and hemicellose.

  13. Binge Drinking PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2010-10-05

    This PSA is based on the October, 2010 CDC Vital Signs report which indicates that drinking too much, including binge drinking, causes more than 79,000 deaths in the U.S. each year and is the third leading preventable cause of death.  Created: 10/5/2010 by Centers for Disease Control and Prevention (CDC).   Date Released: 10/5/2010.

  14. Estabilidad de la capacidad antioxidante y pH en leche humana refrigerada durante 72 horas: estudio longitudinal Stability of the antioxidant capacity and pH of human milk refrigerated for 72 hours: longitudinal study

    Directory of Open Access Journals (Sweden)

    M. Miranda

    2011-08-01

    infant at least for the first six months of life. Its properties include nutrients intake and, particularly, to provide the infant with several beneficial compounds improving his growth and protecting him from the diseases typical of this time period. These properties justify the manipulating processes before its intake in order to promote and warrant the adherence to it, both at the hospital and at home, being more important in premature infants and/or with low birth weight given their increased vulnerability, is spite of the fact that during these processes some of its properties may be partially lost. There exist, therefore, an interest in knowing the impact of the procedures applied to human milk on its qualitative properties, such as the antioxidant capacity. Objective: This work assesses the stability of the antioxidant capacity of human milk during its storage at 4º C, longitudinally from its extraction until 48 h of refrigeration, as well as the pH changes. Method: the milk from 30 healthy women was analyzed. The milk's antioxidant capacity was assessed by the following parameters: total antioxidant capacity and level of malondialdehyde. The results obtained showed that pH decreases gradually from the storage beginning, whereas the antioxidant capacity remains constant for the first 24 hours, with a different result depending on the parameter used, and thereafter significant changes were observed. Conclusions: In case of needing extraction and storage of maternal milk before its consumption, the storage time should be minimized, preferably less than 24 hours in order to preserve the oxidative stress.

  15. Bing and Neel Syndrome

    Directory of Open Access Journals (Sweden)

    S. Jennane

    2012-01-01

    Full Text Available Introduction. We report the case of a Bing and Neel syndrome revealed by an isolated left ptosis. Case Report. a 57-year-old man was followed up since October 2003 for a typical Waldenström’s macroglobulinemia. A first complete remission was obtained with chlorambucil. In August 2004, he relapsed. A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, and cyclophosphamide. In October 2009, the patient presented with an isolated left ptosis revealing a Bing and Neel syndrome. The diagnosis was suspected on MRI and confirmed by the detection in the CSF of a monoclonal IgM similar to the one found in the plasma. A quite good partial remission has been obtained after one course of RDHAP (rituximab, dexamethasone, cytarabine, and cisplatin and 3 courses of RDHOx (rituximab, dexamethasone, cytarabine, and oxaliplatin, in addition to ten intrahectal chemotherapy injections. The treatment was followed by intensification and autologous stem cell transplantation. At D58, the patient died due to a septic shock. Conclusion. BNS is a rare and potentially treatable complication of WM. It should be considered in patients with neurologic symptoms and a history of WM.

  16. Bing and neel syndrome.

    Science.gov (United States)

    Jennane, S; Doghmi, K; Mahtat, E M; Messaoudi, N; Varet, B; Mikdame, M

    2012-01-01

    Introduction. We report the case of a Bing and Neel syndrome revealed by an isolated left ptosis. Case Report. a 57-year-old man was followed up since October 2003 for a typical Waldenström's macroglobulinemia. A first complete remission was obtained with chlorambucil. In August 2004, he relapsed. A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, and cyclophosphamide). In October 2009, the patient presented with an isolated left ptosis revealing a Bing and Neel syndrome. The diagnosis was suspected on MRI and confirmed by the detection in the CSF of a monoclonal IgM similar to the one found in the plasma. A quite good partial remission has been obtained after one course of RDHAP (rituximab, dexamethasone, cytarabine, and cisplatin) and 3 courses of RDHOx (rituximab, dexamethasone, cytarabine, and oxaliplatin), in addition to ten intrahectal chemotherapy injections. The treatment was followed by intensification and autologous stem cell transplantation. At D58, the patient died due to a septic shock. Conclusion. BNS is a rare and potentially treatable complication of WM. It should be considered in patients with neurologic symptoms and a history of WM. PMID:22988532

  17. Nociceptin receptor antagonist SB 612111 decreases high fat diet binge eating

    Science.gov (United States)

    Hardaway, J. Andrew; Jensen, Jennifer; Kim, Michelle; Mazzone, Christopher M.; Sugam, Jonathan A.; Diberto, Jeffrey F.; Lowery-Gionta, Emily G.; Hwa, Lara S.; Pleil, Kristen E.; Bulik, Cynthia M.; Kash, Thomas L.

    2016-01-01

    Binge eating is a dysregulated form of feeding behavior that occurs in multiple eating disorders including binge-eating disorder, the most common eating disorder. Feeding is a complex behavioral program supported through the function of multiple brain regions and influenced by a diverse array of receptor signaling pathways. Previous studies have shown the overexpression of the opioid neuropeptide nociceptin (orphanin FQ, N/OFQ) can induce hyperphagia, but the role of endogenous nociceptin receptor (NOP) in naturally occurring palatability-induced hyperphagia is unknown. In this study we adapted a simple, replicable form of binge eating of high fat food (HFD). We found that male and female C57BL/6J mice provided with daily one-hour access sessions to HFD eat significantly more during this period than those provided with continuous 24 hour access. This form of feeding is rapid and entrained. Chronic intermittent HFD binge eating produced hyperactivity and increased light zone exploration in the open field and light-dark assays respectively. Treatment with the potent and selective NOP antagonist SB 612111 resulted in a significant dose-dependent reduction in binge intake in both male and female mice, and, unlike treatment with the serotonin selective reuptake inhibitor fluoxetine, produced no change in total 24-hour food intake. SB 612111 treatment also significantly decreased non-binge-like acute HFD consumption in male mice. These data are consistent with the hypothesis that high fat binge eating is modulated by NOP signaling and that the NOP system may represent a promising novel receptor to explore for the treatment of binge eating. PMID:27036650

  18. Binge drinking among university students

    Directory of Open Access Journals (Sweden)

    Antonio Augusto Ferreira Carioca

    2012-12-01

    Full Text Available Objective: To investigate the consumption of alcoholic beverages by college students, with an emphasis on practicing alcoholic binge. Methods: We selected randomly 102 students enrolled in different courses at a public university located in the city of Fortaleza. Alcohol consumption and socioeconomic data were investigated with a form. We evaluated both alcohol abuse by transforming the intake in grams of ethanol, such as the presence of alcoholic binge. The statistical package SPSS version 16.0 was used as an operational tool for data analysis, adopting p <0.05 significance level. Results: From the students assessed, 52 (51% were male and 50 (49% were female with a mean age of 21.9 ± 1.9 years. The prevalence of alcohol consumption was 29.4% (n = 30. The binge was observed in 64.7% (n = 11 of men and 46.2% (n = 6 women. The average ethanol intake on each occasion of consumption was 125.4 ± 92g for men and 61.5 ± 42.3 g of ethanol among women, with statistical difference (p = 0.008. Conclusions: The prevalence of alcohol consumption was low, although the binge has been high, especially among men, putting the group at risk to health, demanding the realization of educational activities.

  19. Women, Girls, and Binge Drinking

    Centers for Disease Control (CDC) Podcasts

    2013-08-01

    Bob Brewer, CDC's Alcohol Program Director, goes on the air to discuss the problem of binge drinking among women and girls.  Created: 8/1/2013 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/1/2013.

  20. 中链甘油三酯对72h睡眠剥夺大鼠的认知能力和抗氧化能力的影响%Effect of Medium-chain Triglycerides on the Cognitive Ability and Antioxidant Capacity of Rats with Continuous 72-hour Sleep Deprivation

    Institute of Scientific and Technical Information of China (English)

    马双双; 齐阳; 王莹; 曹翔; 蔡东联; 黄文

    2013-01-01

    目的 研究中链甘油三酯对72h连续睡眠剥夺大鼠的认知能力和抗氧化能力的影响.方法 将30只雄性SD大鼠随机分为正常睡眠组(NC组)、睡眠剥夺组(SD组)、低剂量MCT组(LD组)、中剂量MCT组(MD组)和高剂量MCT组(HD组),用不含MCT的饲料喂养NC组和SD组,用含低、中、高剂量中链甘油三酯的饲料喂养LD组、MD组、HD组.4周后,利用睡眠剥夺箱对大鼠进行睡眠剥夺连续72h后,使用Y型电迷宫来检测大鼠的认知能力,并检测大鼠肝脏中丙二醛(MDA)含量以及超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)的活性.结果 72h连续睡眠剥夺后,SD组大鼠的迷宫反应正确率显著低于其余各组,SD组与NC组相比,MDA含量增加(P<0.05),GSH-Px和SOD活力下降(P <0.05,P<0.01);LD组和MD组的MDA均显著低于SD组(P <0.05,P<0.01),MD组的GSH-Px活性显著高于SD组(P<0.05).MCT对SOD的活性没有显著作用.结论 72h睡眠剥夺使大鼠的认知能力和抗氧化能力明显下降,而中链甘油三酯能改善睡眠剥夺大鼠的认知能力和抗氧化能力.%Objective To investigate the effect of medium-chain triglycerides (MCT) on the cognitive ability and antioxidant capacity of rats with continuous 72-hour sleep deprivation (SD).Methods Thirty rats were randomly divided into the normal control group (NC group),blank sleep deprivation group (SD group),low-dose MCT group (LD group),medium-dose MCT group (MD group) and high dose MCT group (HD group).Sleep deprivation tank was used to deprive the sleep of rats.After continuous 72h,a Y -shaped electric maze was used to measure the learning and memory abilities of rats.Then,the level of GSH-Px,MDA and SOD in rat liver was detected.Results The rats in experimental group had a significantly lower correct response rate than the control group in Y-shaped electric maze(P < 0.05).The activity of GSH-Px and SOD in SD group was significantly lower than NC group (P < 0.05,P

  1. Binge Drinking and Alcohol-Related Problems among U.S-Born Asian Americans

    OpenAIRE

    Iwamoto, Derek; Takamatsu, Stephanie; Castellanos, Jeanett

    2012-01-01

    Binge drinking (five drinks or more in a 2-hour sitting for men, or four or more drinks in a 2-hour sitting for women) and alcohol-related problems are a growing problem among Asian American young adults. The current study examines the socio-cultural (i.e., generational status and ethnic identity) determinants of binge drinking and alcohol-related problems across U.S.-born, young adult, Asian American ethnic groups. Data were collected from 1,575 Asian American undergraduates from a public un...

  2. Nociceptin receptor antagonist SB 612111 decreases high fat diet binge eating.

    Science.gov (United States)

    Hardaway, J Andrew; Jensen, Jennifer; Kim, Michelle; Mazzone, Christopher M; Sugam, Jonathan A; Diberto, Jeffrey F; Lowery-Gionta, Emily G; Hwa, Lara S; Pleil, Kristen E; Bulik, Cynthia M; Kash, Thomas L

    2016-07-01

    Binge eating is a dysregulated form of feeding behavior that occurs in multiple eating disorders including binge-eating disorder, the most common eating disorder. Feeding is a complex behavioral program supported through the function of multiple brain regions and influenced by a diverse array of receptor signaling pathways. Previous studies have shown the overexpression of the opioid neuropeptide nociceptin (orphanin FQ, N/OFQ) can induce hyperphagia, but the role of endogenous nociceptin receptor (NOP) in naturally occurring palatability-induced hyperphagia is unknown. In this study we adapted a simple, replicable form of binge eating of high fat food (HFD). We found that male and female C57BL/6J mice provided with daily one-hour access sessions to HFD eat significantly more during this period than those provided with continuous 24h access. This form of feeding is rapid and entrained. Chronic intermittent HFD binge eating produced hyperactivity and increased light zone exploration in the open field and light-dark assays respectively. Treatment with the potent and selective NOP antagonist SB 612111 resulted in a significant dose-dependent reduction in binge intake in both male and female mice, and, unlike treatment with the serotonin selective reuptake inhibitor fluoxetine, produced no change in total 24-h food intake. SB 612111 treatment also significantly decreased non-binge-like acute HFD consumption in male mice. These data are consistent with the hypothesis that high fat binge eating is modulated by NOP signaling and that the NOP system may represent a promising novel receptor to explore for the treatment of binge eating.

  3. Google Maps -selainsovelluksen toteutus Bing Mapsilla

    OpenAIRE

    Orava, Antti

    2014-01-01

    Opinnäytetyön aiheena oli kehitystyö Google Mapsin APIa käyttävään selainsovellukseen. Kehitystyön tarkoituksena oli lisätä sovellukseen tuki Bing Mapsille. Tuki Bing Mapsille haluttiin, koska osa Bing Mapsin satelliittikuvista on Google Mapsin satelliittikuvia parempia. Tavoitteena oli toteuttaa kaikki alkuperäisen sovelluksen työkalut myös Bing Mapsin APIlla. Iso osa työstä koski polygonien piirtämistä kartalle sekä piirrettyjen polygonien muokkausta. Työ toteutettiin JavaScript-ohjelmo...

  4. Effect of eating rate on binge size in Bulimia Nervosa

    OpenAIRE

    Kissileff, Harry R.; Zimmerli, Ellen J.; Torres, Migdalia I; Devlin, Michael J.; Walsh, B. Timothy

    2007-01-01

    Effect of eating rate on binge size in bulimia nervosa. Bulimia Nervosa (BN) is an eating disorder characterized by recurrent episodes of binge eating. During binge eating episodes, patients often describe the rapid consumption of food, and laboratory studies have shown that during binges patients with BN eat faster than normal controls (NC), but the hypothesis that a rapid rate of eating contributes to the excessive intake of binge meals has not yet been experimentally tested. The aim of thi...

  5. Moderators of post-binge eating negative emotion in eating disorders.

    Science.gov (United States)

    De Young, Kyle P; Lavender, Jason M; Wonderlich, Stephen A; Crosby, Ross D; Engel, Scott G; Mitchell, James E; Crow, Scott; Peterson, Carol B; Le Grange, Daniel

    2013-03-01

    The purpose of this study was to test the impact of two variables on post-binge eating negative emotion in a combined sample of women with anorexia nervosa (AN; n = 47) and bulimia nervosa (BN; n = 121). Participants completed two weeks of an ecological momentary assessment protocol during which they provided multiple daily ratings of overall negative affect and guilt and reported eating disorder behaviors including binge eating and self-induced vomiting. The results indicate that both overall negative affect and guilt exhibited a statistically significantly decrease in the hour immediately following binge eating episodes. The decrease in guilt, but not overall negative affect, was moderated by eating disorder diagnosis and the tendency to engage in self-induced vomiting. Specifically, individuals with BN reported a greater reduction in guilt than those with AN, and individuals who did not typically engage in self-induced vomiting reported more decreases in guilt than those who typically engaged in self-induced vomiting. This study extends the existing literature on the relationship between negative affect and eating disorder behaviors, suggesting guilt as a potentially relevant facet of negative affect in the maintenance of binge eating. In addition, the findings indicate that two individual differences, eating disorder diagnosis and self-induced vomiting, may influence the trajectory of guilt following binge eating episodes.

  6. Treatment of binge eating disorder.

    Science.gov (United States)

    Wilson, G Terence

    2011-12-01

    The two specialty psychological therapies of CBT and IPT remain the treatments of choice for the full range of BED patients, particularly those with high levels of specific eating disorder psychopathology such as overvaluation of body shape and weight. They produce the greatest degree of remission from binge eating as well as improvement in specific eating disorder psychopathology and associated general psychopathology such as depression. The CBT protocol evaluated in the research summarized above was the original manual from Fairburn and colleagues. Fairburn has subsequently developed a more elaborate and sophisticated form of treatment, namely, enhanced CBT (CBT-E) for eating disorders. Initial research suggests that CBT-E may be more effective than the earlier version with bulimia nervosa and Eating Disorder Not Otherwise Specified patients. CBT-E has yet to be evaluated for the treatment of BED, although it would currently be the recommended form of CBT. Of relevance in this regard is that the so-called broad form of the new protocol includes 3 optional treatment modules that could be used to address more complex psychopathology in BED patients. One of the modules targeted at interpersonal difficulties is IPT, as described earlier in this chapter. Thus, the broader protocol could represent a combination of the two currently most effective therapies for BED. Whether this combined treatment proves more effective than either of the components alone, particularly for a subset of BED patients with more complex psychopathology, remains to be tested. CBT-E also includes a module designed to address what Fairburn terms “mood intolerance” (problems in coping with negative affect) that can trigger binge eating and purging. The content and strategies of this mood intolerance module overlap with the emotional regulation and distress tolerance skills training of Linehan's dialectical behavior therapy (DBT). Two randomized controlled trials have tested the efficacy of an

  7. Fox reimbedding and Bing submanifolds

    CERN Document Server

    Nakamura, Kei

    2012-01-01

    Let M be an orientable closed connected 3-manifold. We introduce the notion of amalgamated Heegaard genus of M with respect to a closed separating 2-manifold F, and use it to show that the following two statements are equivalent: (i) a compact connected 3-manifold Y can be embedded in M so that the exterior of the image of Y is a union of handlebodies; and (ii) a compact connected 3-manifold Y can be embedded in M so that every knot in M can be isotoped to lie within the image of Y . Our result can be regarded as a common generalization of the reimbedding theorem by Fox [Fox48] and the characterization of 3-sphere by Bing [Bin58], as well as more recent results of Hass and Thompson [HT89] and Kobayashi and Nishi [KN94].

  8. Which facets of impulsivity predict binge drinking?

    OpenAIRE

    2016-01-01

    Background Impulsive binge drinking is a serious public health issue, and to reveal predisposing factors to this consumption pattern is, therefore, required. Impulsivity-related traits are important predictors of alcohol use and abuse. Nonetheless, previous research in binge drinking has been confounded by various definitions and cut-off scores, implying that existing studies contributed to limited comprehension on the specific role of different impulsivity facets. The current study thus dise...

  9. Den tredje spiseforstyrrelse - Binge Eating Disorder

    DEFF Research Database (Denmark)

    Schousboe, Birgitte Hartvig

    2010-01-01

    Mennesker med Binge Eating Disorder indtager større mængder mad uden at være sultne. Overspisningen kan dulme svære følelser, men medfører typisk ekstremt ubehag og skam. Mennesker, der lider af spiseforstyrrelsen Binge Eating Disorder (i daglig tale kaldet BED), har ofte problemer med overvægt, og...

  10. Concordance of Bing Doubles and Boundary Genus

    Science.gov (United States)

    Livingston, Charles; van Cott, Cornelia A.

    2011-11-01

    Cha and Kim proved that if a knot K is not algebraically slice, then no iterated Bing double of K is concordant to the unlink. We prove that if K has nontrivial signature $\\sigma$, then the n-iterated Bing double of K is not concordant to any boundary link with boundary surfaces of genus less than $2^{n-1}\\sigma$. The same result holds with $\\sigma$ replaced by $2\\tau$, twice the Ozsvath-Szabo knot concordance invariant.

  11. Diagnosis and management of binge eating disorder

    OpenAIRE

    Bulik, Cynthia M.; Brownley, Kimberly A.; Shapiro, Jennifer R.

    2007-01-01

    This paper addresses current issues regarding the diagnosis and management of binge eating disorder (BED). Controversies in diagnosis include the lack of empirically validated criteria, the lack of a universally recognized operational definition of a "binge episode", and the lack of age-appropriate assessment instruments in light of growing reports of BED among children and adolescents. For adults with BED, several pharmacological and behavioral treatments have shown promise...

  12. Insights revealed by rodent models of sugar binge eating.

    Science.gov (United States)

    Murray, Susan M; Tulloch, Alastair J; Chen, Eunice Y; Avena, Nicole M

    2015-12-01

    Binge eating is seen across the spectrum of eating disorder diagnoses as well as among individuals who do not meet diagnostic criteria. Analyses of the specific types of foods that are frequently binged upon reveal that sugar-rich items feature prominently in binge-type meals, making the effects of binge consumption of sugar an important focus of study. One avenue to do this involves the use of animal models. Foundational and recent studies of animal models of sugar bingeing, both outlined here, lend insight into the various neurotransmitters and neuropeptides that may participate in or be altered by this behavior. Further, several preclinical studies incorporating sugar bingeing paradigms have explored the utility of pharmacological agents that target such neural systems for reducing sugar bingeing in an effort to enhance clinical treatment. Indeed, the translational implications of findings generated using animal models of sugar bingeing are considered here, along with potential avenues for further study.

  13. Prevalence and correlates of binge eating in seasonal affective disorder

    OpenAIRE

    Donofry, Shannon D.; Roecklein, Kathryn A.; Kelly J. Rohan; Wildes, Jennifer E.; Kamarck, Marissa L.

    2014-01-01

    Eating pathology in Seasonal Affective Disorder (SAD) may be more severe than hyperphagia during winter. Although research has documented elevated rates of subclinical binge eating in women with SAD, the prevalence and correlates of BED in SAD remain largely uncharacterized. We examined the prevalence and correlates of binge eating, weekly binge eating with distress, and BED as defined by the DSM-IV-TR in SAD. We also tested whether binge eating exhibits a seasonal pattern among individuals w...

  14. Comparisons of energy intake and energy expenditure in overweight and obese women with and without binge eating disorder

    Science.gov (United States)

    The purpose of this study was to determine whether there are differences in energy intake or energy expenditure that distinguish obese women with and without binge eating disorder (BED). Seventeen obese women with BED and 17 obese controls completed random 24-hour dietary recall interviews, and had ...

  15. Binge Drinking in Young Adults: Data, Definitions and Determinants

    Science.gov (United States)

    Courtney, Kelly E.; Polich, John

    2009-01-01

    Binge drinking is an increasingly important topic in alcohol research, but the field lacks empirical cohesion and definitional precision. The present review summarizes findings and viewpoints from the scientific binge-drinking literature. Epidemiological studies quantify the seriousness of alcohol-related problems arising from binge drinking, with…

  16. Evaluation of Extinction as a Functional Treatment for Binge Eating

    Science.gov (United States)

    Bosch, Amanda; Miltenberger, Raymond G.; Gross, Amy; Knudson, Peter; Breitwieser, Carrie Brower

    2008-01-01

    Binge eating is a serious behavior problem exhibited by individuals diagnosed with binge eating disorder and bulimia nervosa. Binge eating is thought to be maintained by automatic negative reinforcement in the form of relief from negative emotional responding. Current treatments produce only moderate abstinence, perhaps because they do not attempt…

  17. Self-critical perfectionism and binge eating symptoms: a longitudinal test of the intervening role of psychological need frustration.

    Science.gov (United States)

    Boone, Liesbet; Vansteenkiste, Maarten; Soenens, Bart; Van der Kaap-Deeder, Jolene; Verstuyf, Joke

    2014-07-01

    Although abundant research has shown that self-critical perfectionism relates to binge eating symptoms, fewer studies have addressed the role of intervening processes that might explain why this is the case. Grounded in self-determination theory, we hypothesized that self-critical perfectionism would relate to an increased risk for binge eating symptoms because it engenders frustration of the psychological needs for autonomy, competence, and relatedness. This hypothesis was tested in a sample of 566 adolescents (72% female; mean age = 13.3 years) using a 3-wave longitudinal study with a 6-month interval. Structural equation modeling analyses showed that self-critical perfectionism related to increases in psychological need frustration which, in turn, predicted increases in binge eating symptoms. Structural relations were found to be equivalent for males and females. Theoretical and clinical implications of these findings are discussed.

  18. Usefulness of Heavy Drinking and Binge Drinking for the Diagnosis of Alcohol Use Disorder

    Science.gov (United States)

    Kim, Seong Gu; Sung, Han Na

    2016-01-01

    Background This research investigated the sensitivity and specificity of heavy and binge drinking for screening of alcohol use disorder. Methods This retrospective study was conducted with 976 adults who visited the Sun Health Screening Center for health screenings in 2015. Daily drinking amount, drinking frequency per week, and weekly drinking amount were investigated. Using criteria from the National Institute on Alcohol Abuse and Alcoholism, participants were classified as normal drinkers, heavy drinkers, or binge drinkers, and grouped by age and sex. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of heavy and binge drinking were compared for the diagnosis of alcohol abuse and alcohol dependence using the Diagnostic and Statistical Manual of Mental Disorders (DSM) 4th edition-text revision and alcohol use disorder using the DSM 5th edition. Results The sensitivity of heavy and binge drinking for the diagnosis of alcohol abuse, alcohol dependence, and alcohol use disorder were 51.7%, 43.8%, and 35.3%, and 69.0%, 62.5%, and 48.2%, respectively. The specificity of these were 90.1%, 91.7%, and 95.5%, and 84.3%, 86.8%, and 91.2%, respectively. The PPV of these were 24.8%, 40.5%, and 72.7%, and 21.7%, 38.0%, and 65.2%, respectively. The NPV of these were 96.7%, 92.6%, and 81.2%, and 97.8%, 94.7%, and 83.7%, respectively. Conclusion Heavy and binge drinking did not show enough diagnostic power to screen DSM alcohol use disorder although they did show high specificity and NPV. PMID:27468339

  19. Binge Drinking and the Independent School Student

    Science.gov (United States)

    Baggish, Rosemary; Wells, Peter

    2013-01-01

    When questioned about illegal, mood-altering substance use, 15,743 high school students surveyed in the last three years with the "Independent School Health Check" said alcohol is most commonly used. For the 30 days prior to filling out the survey, 33.9 percent of the students reported drinking, and 24.2 percent reported binge drinking…

  20. Topiramate: use in binge eating disorder?

    Directory of Open Access Journals (Sweden)

    Mauro Gentile

    2012-01-01

    Full Text Available Introduction: Topiramate was serendipitously synthesized in 1979 during research aimed at developing a fructose-1,6-diphosphatase inhibitor that might be used in the treatment of diabetes mellitus. Some investigators have suggested it might be used in the treatment of binge eating disorder (BED. The aim of this review was to evaluate current knowledge and opinions on this topic. Materials and methods: We conducted a search of five electronic databases (PubMed, Embase, Nice, Cochrane, Cinahl using the search strategy ‘‘topiramate’’ AND ‘‘binge’’, ‘‘binge eating disorder.’’ No time limits were applied, and only reports of randomized controlled trials were included in our analysis. Results: In clinical studies, topiramate use has been associated with significant weight loss mediated by reductions in the frequency of bingeing episodes. The most common side effects of the drug are paresthesias, but nephrolithiasis, oligohydrosis, and dizziness have also been described. Conclusions: Available data are limited, but the literature we reviewed suggests that topiramate can be useful in the medical treatment of BED, reducing both body weight and binge episodes. Side effects are not negligible. Before topiramate can be regarded as a good tool for the treatment of BED, further data must be obtained from longer, methodologically correct studies of larger populations.

  1. Integrative Response Therapy for Binge Eating Disorder

    Science.gov (United States)

    Robinson, Athena

    2013-01-01

    Binge eating disorder (BED), a chronic condition characterized by eating disorder psychopathology and physical and social disability, represents a significant public health problem. Guided self-help (GSH) treatments for BED appear promising and may be more readily disseminable to mental health care providers, accessible to patients, and…

  2. 168 Hours Salt Fog Test

    International Nuclear Information System (INIS)

    This report explained the test conducted in salt fog chamber to evaluate the effectiveness of mild steel, coated with rust converter, for 168 hours in artificial seawater exposure. The samples were compared with mild steel coated with commercial primer. The tests were conducted followed ASTM B117. Individual pictures were taken of each sample before the tests began, at 24, 48, 72, 96, 120, 144 and 168 hours to see the progression of the corrosion. Results showed that the samples coated with rust converter provide a good significant protection against corrosion phenomenon than the samples coated with commercial primer that available in the market. (author)

  3. Investigative Analysis on the wounded of Deyang during the first 72 hours after 4/20 earthquake in Lushan%“4.20”芦山地震72小时内德阳地区伤员伤害调查与分析

    Institute of Scientific and Technical Information of China (English)

    王森; 罗永清; 陈刚; 鄢涛; 姜伟; 赵鲁平; 张标; 谭鸿; 胡壮俐; 黎君彦; 林涛

    2013-01-01

    Objective To analyze characteristics of the wounded and effect of remedy at earthquake in Lushan, and to review the emergency response plan and the measures how to prevent injuries. Methods Data of the 25 wounded in earthquake in Deyang hospital in between April 20 and April 23, 2013 were collected. A review on triage, treatments, and contents was conducted. Results Of the 25 wounded, 20 of them were with single injury (80%) and 5 with multiple injuries (20%). The incidence of single injury was higher than those multiple trauma ,P<0.05. The incidence of extremities, trauma, and soft tissue injury were higher than the others. The main flow of wounded (92%) occurred within the first 24 hours after earthquake, much higher than any other time ,P<0.05. The number of patients aged between 19 and 45 years old was larger than any other age group,P<0.01. Conclusion With extensive experience and a considerable emergency response plan which had helped form an efficient emergency medical service system. It is considered being effective in shortening the time to respond, as well as enhancing the capability in a rescue mission.%目的:分析“4.20”芦山地震中德阳地区地震伤员的伤情特点、救治过程和效果,探讨灾难救援中应急预案应用和防范地震伤害的措施。方法收集四川省德阳市人民医院在2013年4月20日~4月23日收治的25例地震伤员资料,分析伤员伤害情况,回顾早期救治分类、救治方法和内容。结果25例伤员中,共有32处损伤,单个部位伤20例,占80.00%;多部位伤5例,占20.00%,单个部位伤明显多于多部位伤,P<0.05;四肢损伤、体表和软组织损伤多于其他部位损伤;伤员流在震后第1天最多,占92.00%,明显多于其他时间,P<0.05;19~45岁年龄组伤员多于其他年龄组,P<0.05。结论德阳市人民医院具有丰富的急救经验和完善的应急预案,并形成了科学、高效的急救救援体

  4. Extended Library Hours

    OpenAIRE

    Devarai, Rajashekhar S.; Devarai, Kanyakumari S.

    1997-01-01

    Extension of library hours is useful both for public & LIS professional. Five laws, need for extended hours, problems of extended library hours, implication of extended library hours. ROCLOLIB are the related topics covered in the paper to highlight the importance of extended library hours.

  5. Preference for safe over risky options in binge eating

    OpenAIRE

    Neveu, Rémi; Fouragnan, Elsa; Barsumian, Franck; Carrier, Edouard; Lai, Massimo; Nicolas, Alain; Neveu, Dorine; Coricelli, Giorgio

    2016-01-01

    Binge eating has been usually viewed as a loss of control and an impulsive behavior. But, little is known about the actual behavior of binging patients (prevalently women) in terms of basic decision-making under risk or under uncertainty. In healthy women, stressful cues bias behavior for safer options, raising the question of whether food cues that are perceived as threatening by binging patients may modulate patients’ behaviors towards safer options. A cross-sectional study was conducted wi...

  6. Jocks, Gender, Binge Drinking, and Adolescent Violence

    OpenAIRE

    Miller, Kathleen E.; Melnick, Merrill J.; Farrell, Michael P.; Sabo, Donald F.; Barnes, Grace M.

    2006-01-01

    Previous research has suggested a link between athletic involvement and elevated levels of adolescent violence outside the sport context. The present study expanded on this literature by positing differences in the sport/violence relationship across dimensions of athletic involvement (athletic participation vs. jock identity), type of violence (family vs. nonfamily), and gender, as well as examining the impact of binge drinking on the sport/violence relationship. Regression analyses using a s...

  7. Bing Xin:The Teller of Tales

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    AT 9 p.m. on February 28, 1999,contemporary Chinese masterand famous writer Bing Xinpassed away quietly. As she wrote in herwill, "I quietly came into the world and Iwill leave it the same way." The entireliterary circle as well as other membersof society attended her funeral to mournher passing. Thousands of fire-red rosesencircled her. Several generations of herreaders came from all parts of thecountry to pay tribute to the centenarian

  8. Binge Eating Disorder and Food Addiction

    OpenAIRE

    Gearhardt, Ashley N.; White, Marney A.; POTENZA, MARC N.

    2011-01-01

    Binge eating disorder (BED) shares many characteristics with addictive behaviors (e.g., diminished control, continued use despite negative consequences), and a body of scientific literature is building to support addiction conceptualizations of problematic eating. Despite similarities, BED and “food addiction” may represent unique yet overlapping conditions. Although the exploration of food addiction is relatively new, understanding the relationship between food addiction and BED may be infor...

  9. Topiramate: use in binge eating disorder?

    OpenAIRE

    Mauro Gentile; Giovanni Scanelli

    2012-01-01

    Introduction: Topiramate was serendipitously synthesized in 1979 during research aimed at developing a fructose-1,6-diphosphatase inhibitor that might be used in the treatment of diabetes mellitus. Some investigators have suggested it might be used in the treatment of binge eating disorder (BED). The aim of this review was to evaluate current knowledge and opinions on this topic. Materials and methods: We conducted a search of five electronic databases (PubMed, Embase, Nice, Cochrane, Cinahl)...

  10. Binge drinking in pregnancy and risk of fetal death

    DEFF Research Database (Denmark)

    Strandberg-Larsen, Katrine; Nielsen, Naja Rod; Grønbaek, Morten;

    2008-01-01

    episodes was related to the risk of early (at or before 12 completed weeks) or late (13-21 completed weeks) spontaneous abortion. However, three or more binge episodes showed an adjusted hazard ratio of 1.56 (95% confidence interval 1.01-2.40) for stillbirth (22 or more completed weeks) relative...... to nonbinge drinkers. Women with an average intake of three or more drinks per week and two or more binge drinking episodes had a hazard ratio of 2.20 (95% confidence interval 1.73-2.80) compared with women with no average intake and no binge drinking. CONCLUSION: Binge drinking three or more times during...

  11. The Effect of mGluR5 Antagonism During Binge Drinkingon Subsequent Ethanol Intake in C57BL/6J Mice: Sex- and Age-Induced Differences

    Science.gov (United States)

    Cozzoli, Debra K.; Strong-Kaufman, Moriah N.; Tanchuck, Michelle A.; Hashimoto, Joel G.; Wiren, Kristine M.; Finn, Deborah A.

    2016-01-01

    Background Binge ethanol (EtOH) intake during adolescence leads to an array of behavioral and cognitive consequences including elevated intake of EtOH during adulthood, with female mice showing greater susceptibility than males. Administration of the metabotropic glutamate receptor 5 (mGluR5) antagonist 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine (MTEP) has been shown to reduce EtOH self-administration in adult male mice, but little is known about its effect on female and adolescent mice. Methods MTEP (0, 10, 20 mg/kg, i.p.) was repeatedly administered to female and male, adult and adolescent C57BL/6J mice during binge sessions using the scheduled high alcohol consumption paradigm. Next, we assessed whether MTEP administration during binge altered the subsequent 24-hour EtOH intake following a period of abstinence. Finally, we investigated whether MTEP administration during binge followed by an abstinence period altered mRNA of glutamatergic genes within the nucleus accumbens of female mice. Results MTEP significantly decreased binge EtOH intake in all mice, but only female mice exhibited altered subsequent 24-hour EtOH intake. Interestingly, the alteration in subsequent EtOH intake in female animals was age dependent, with adolescent exposure to MTEP during binge decreasing 24-hour intake and adult exposure to MTEP during binge increasing 24-hour intake. Finally, while there were no effects of MTEP pretreatment on the genes examined, there was a robust age effect found during analysis of mGluR1 (Grm1), mGluR5 (Grm5), the NR2A subunit of the NMDA receptor (Grin2a), phosphatidylinositol 3-kinase (Pik3r1), mammalian target of rapamycin (Mtor), and extracellular signal-regulated kinase (Mapk1) mRNA, with adolescent female animals having lower expression than their adult counterparts. Conclusions Collectively, the present findings add to existing evidence implicating the contribution of long-term effects of adolescent binge drinking to enhance alcohol abuse in

  12. Differential mesocorticolimbic responses to palatable food in binge eating prone and binge eating resistant female rats.

    Science.gov (United States)

    Sinclair, Elaine B; Culbert, Kristen M; Gradl, Dana R; Richardson, Kimberlei A; Klump, Kelly L; Sisk, Cheryl L

    2015-12-01

    Binge eating is a key symptom of many eating disorders (e.g. binge eating disorder, bulimia nervosa, anorexia nervosa binge/purge type), yet the neurobiological underpinnings of binge eating are poorly understood. The mesocorticolimbic reward circuit, including the nucleus accumbens and the medial prefrontal cortex, is likely involved because this circuit mediates the hedonic value and incentive salience of palatable foods (PF). Here we tested the hypothesis that higher propensity for binge eating is associated with a heightened response (i.e., Fos induction) of the nucleus accumbens and medial prefrontal cortex to PF, using an animal model that identifies binge eating prone (BEP) and binge eating resistant (BER) rats. Forty adult female Sprague-Dawley rats were given intermittent access to PF (high fat pellets) 3×/week for 3 weeks. Based on a pattern of either consistently high or consistently low PF consumption across these feeding tests, 8 rats met criteria for categorization as BEP, and 11 rats met criteria for categorization as BER. One week after the final feeding test, BEP and BER rats were either exposed to PF in their home cages or were given no PF in their home cages for 1h prior to perfusion, leading to three experimental groups for the Fos analysis: BEPs given PF, BERs given PF, and a No PF control group. The total number of Fos-immunoreactive (Fos-ir) cells in the nucleus accumbens core and shell, and the cingulate, prelimbic, and infralimbic regions of the medial prefrontal cortex was estimated by stereological analysis. PF induced higher Fos expression in the nucleus accumbens shell and core and in the prelimbic and infralimbic cortex of BEP rats compared to No PF controls. Throughout the nucleus accumbens and medial prefrontal cortex, PF induced higher Fos expression in BEP than in BER rats, even after adjusting for differences in PF intake. Differences in the neural activation pattern between BEP and BER rats were more robust in prefrontal cortex

  13. Differential mesocorticolimbic responses to palatable food in binge eating prone and binge eating resistant female rats.

    Science.gov (United States)

    Sinclair, Elaine B; Culbert, Kristen M; Gradl, Dana R; Richardson, Kimberlei A; Klump, Kelly L; Sisk, Cheryl L

    2015-12-01

    Binge eating is a key symptom of many eating disorders (e.g. binge eating disorder, bulimia nervosa, anorexia nervosa binge/purge type), yet the neurobiological underpinnings of binge eating are poorly understood. The mesocorticolimbic reward circuit, including the nucleus accumbens and the medial prefrontal cortex, is likely involved because this circuit mediates the hedonic value and incentive salience of palatable foods (PF). Here we tested the hypothesis that higher propensity for binge eating is associated with a heightened response (i.e., Fos induction) of the nucleus accumbens and medial prefrontal cortex to PF, using an animal model that identifies binge eating prone (BEP) and binge eating resistant (BER) rats. Forty adult female Sprague-Dawley rats were given intermittent access to PF (high fat pellets) 3×/week for 3 weeks. Based on a pattern of either consistently high or consistently low PF consumption across these feeding tests, 8 rats met criteria for categorization as BEP, and 11 rats met criteria for categorization as BER. One week after the final feeding test, BEP and BER rats were either exposed to PF in their home cages or were given no PF in their home cages for 1h prior to perfusion, leading to three experimental groups for the Fos analysis: BEPs given PF, BERs given PF, and a No PF control group. The total number of Fos-immunoreactive (Fos-ir) cells in the nucleus accumbens core and shell, and the cingulate, prelimbic, and infralimbic regions of the medial prefrontal cortex was estimated by stereological analysis. PF induced higher Fos expression in the nucleus accumbens shell and core and in the prelimbic and infralimbic cortex of BEP rats compared to No PF controls. Throughout the nucleus accumbens and medial prefrontal cortex, PF induced higher Fos expression in BEP than in BER rats, even after adjusting for differences in PF intake. Differences in the neural activation pattern between BEP and BER rats were more robust in prefrontal cortex

  14. Impact of mean fasting glucose over the first 72 hours on in-hospital outcomes of patients with ST-segment elevation myocardial infarction%平均空腹血糖对ST段抬高型心肌梗死患者住院预后的影响

    Institute of Scientific and Technical Information of China (English)

    刘品明; 林飞宁; 方昶; 张少玲; 王景峰

    2010-01-01

    Objective To evaluate the impact of mean fasting glucose over the first 72 hours after admission on in-hospital outcomes in patients with ST-segment elevation myocardial infarction ( STEMI ).Methods The data of 357 non-diabetic patients hospitalized with STEMI were collected from the database of Sun Yat-sen Memorial Hospital, affiliated to Sun Yat-sen University between January 2006 and April 2009.The patients were categorized into 3 groups according to mean fasting glucose over the first 72 hours after admission: < 5.6 ( n = 165 ), 5.6 - 7.0 ( n = 122 ) and > 7.0 mmol/L ( n = 70). Clinical characteristics,therapeutic approaches and the incidence of heart failure, malignant arrhythmias, and death during hospitalization were compared among groups. Multivariate logistic regression analysis was performed to determine the association between risk factors and in-hospital outcomes. Receiver-operator characteristic (ROC) curve was generated to assess the power of mean fasting glucose on predicting in-hospital death. Results Age, past history of infarction and early revascularization therapy were similar among groups. Heart rate on admission, white blood cell count, peak CK-MB level, and proportion of extensive anterior infarction were increased in proportion to higher mean fasting glucose levels. Higher mean fasting glucose levels were associated with increased risk of reduced left ventricular ejection fraction, heart failure characterized by higher Killip class, and malignant arrhythmias. After multivariate adjustment, mean fasting glucose remained to be an independent risk factor for increased in-hospital death of patients with STEMI (OR = 1.31, 95% CI: 1.10 - 1. 57;P =0. 003). Mean fasting glucose had the higher area under the ROC curve than admission glucose or fasting glucose after admission based on single measurement (0. 758, 0. 674and 0. 717;P < 0. 001 ). Conclusion Mean fasting glucose during first 72 hours after admission is an independent predictor for in

  15. Differential strain vulnerability to binge eating behaviors in rats.

    Science.gov (United States)

    Hildebrandt, Britny A; Klump, Kelly L; Racine, Sarah E; Sisk, Cheryl L

    2014-03-29

    Binge eating is a significantly heritable phenotype, but efforts to detect specific risk genes have fallen short. Identification of animal strain differences in risk for binge eating could highlight genetic differences across individuals of the same species that can be exploited in future animal and molecular genetic research. The current study aimed to explore strain differences in risk for binge eating in Sprague-Dawley versus Wistar female rats using the Binge Eating Resistant/Binge Eating Prone model. A sample of male Sprague-Dawley rats, a known low-risk group for binge eating, was included as a comparison group. A total of 83 rats (23 Wistar females, 30 Sprague-Dawley females, 30 Sprague-Dawley males) completed a protocol of intermittently administered, palatable food. Binge eating prone (BEP) and binge eating resistant (BER) rats were identified using a tertile approach. Sprague-Dawley female rats consumed the highest amount of palatable food and were more likely to be classified as BEP compared to Wistar female and Sprague-Dawley male rats. Wistar female rats were not significantly different from Sprague-Dawley male rats in their palatable food intake and tendency to be classified as BER rather than BEP. Sprague-Dawley female rats appear to be a particularly vulnerable genotype for binge eating. Comparisons between this group and others could help identify specific genetic/biological factors that differentiate it from lower risk groups. The reward system, linked to binge eating in humans, is a possible candidate to explore. Strain differences in the reward system could help increase understanding of individual differences in risk for binge eating in humans. PMID:24480076

  16. Binge or control? : assessment of the validity, treatment and underlying mechanisms of Binge Eating Disorder

    NARCIS (Netherlands)

    Dingemans, Alexandra

    2009-01-01

    This thesis focuses on patients with Binge Eating Disorder. The thesis consists of three parts. In the first part the validity of the diagnosis of BED will be discussed. The results of two literature reviews and an empirical cross-sectional study suggested that BED is a distinct eating disorder and

  17. De oorsprong van Art Nouveau - Het Bing imperium

    NARCIS (Netherlands)

    Weisberg, Gabriel P.; Becker, Edwin; Posseme, Evelyne

    2004-01-01

    The opening of Sigmund Bing's gallery L'Art Nouveau had been an eagerly expected event in the Paris art world throughout the latter half of 1895, since Bing first announced that he would be soon exhibiting artistic furniture. The doors finally opened on 26 December 1895 as visitors poured in at 22 R

  18. Alexithymia, Affect Regulation, and Binge Drinking in College Students

    Science.gov (United States)

    Barth, F. Diane

    2015-01-01

    Numerous programs have been instituted to address the widely recognized problem of binge drinking in college students, with some excellent results. Yet binge drinking is commonly still viewed as a socially acceptable form of relaxing and bonding with peers, often with the stated goal of getting as drunk as possible as quickly as possible. The…

  19. Binge drinking, drinking frequency, and risk of ischaemic heart disease

    DEFF Research Database (Denmark)

    Skov-Ettrup, Lise; Eliasen, Marie; Ekholm, Ola;

    2011-01-01

    INTRODUCTION: Light-to-moderate alcohol drinking is associated with a decreased risk of ischaemic heart disease (IHD). However, drinking heavily and in binges has been suggested to increase IHD risk. This complexity makes the issue of binge drinking within the light-to-moderate alcohol range...

  20. Binging and Nonbinging Women's Emotional Reactions to Television Advertising.

    Science.gov (United States)

    Raupp, Carol D.; And Others

    This examination of the reactions of women who are binge eaters to television advertising tested three hypotheses: (1) women who binge experience more negative emotional reactions to television ads, especially ads emphasizing food or weight control; (2) highly feminine women, or women with large real-ideal sex role gaps, react negatively; and (3)…

  1. Binge Eating and Weight Control: The Role of Experiential Avoidance

    Science.gov (United States)

    Lillis, Jason; Hayes, Steven C.; Levin, Michael E.

    2011-01-01

    Two thirds of the adults in the United States are overweight or obese. Binge eating is a barrier to treatment adherence and sustained weight loss, and can be seen as a form of experiential avoidance. The current study analyzed the impact of binge eating on weight reduction in a previously published study of a 1-day acceptance and commitment…

  2. College Student Binge Eating: Insecure Attachment and Emotion Regulation

    Science.gov (United States)

    Han, Suejung; Pistole, M. Carole

    2014-01-01

    Because college students who have accomplished developmental tasks less effectively may be at risk for detrimental behavior such as binge eating, we examined emotion regulation as a mediator of attachment insecurity and binge eating. Based on undergraduate and graduate student responses to a Web-based survey ("N" = 381), structural…

  3. Further Clinical Validation of the Binge-Eating Scale.

    Science.gov (United States)

    Ross, Steven M.; Todt, Ellen H.

    Previous research has shown significant correlations between the Binge Eating Scale (BES) and the Cognitive Factors Scale (CFS) using obese subjects who were not selected based on criteria for eating disorders. To determine if similar relationships between binging severity and cognitive factors would hold for subjects who did meet the criteria for…

  4. The overlap between binge eating disorder and substance use disorders

    DEFF Research Database (Denmark)

    Schreiber, Liana R N; Odlaug, Brian Lawrence; Grant, Jon E

    2013-01-01

    BACKGROUND AND AIMS: Binge eating disorder (BED) is a relatively common condition, especially in young adult females, and is characterized by chronic over-consumption of food resulting in embarrassment, distress, and potential health problems. It is formally included as a disorder in DSM-5...... for the first time, an acknowledgement to its debilitating nature. This article explores the overlap between binge eating disorder and substance use disorders (SUD). METHODS: The bibliographic search was a computerized screen of PubMed databases from January 1990 to the present. Binge eating disorder, substance...... use disorder, binging, obesity, food addiction, comorbidity, dopamine, opioid, serotonin, glutamate, and pharmacological treatment were the keywords used in searching. RESULTS: BED shares similar phenomenology to SUD, including significant urges to engage in binging episodes, resulting in distress...

  5. Mouse Strain- and Age-dependent Effects of Binge Methamphetamine on Dopaminergic Signaling

    OpenAIRE

    Good, Renee L.; Liang, Li-Ping; Patel, Manisha; Radcliffe, Richard A.

    2011-01-01

    We have shown that a single “binge” dose of methamphetamine (Meth) in mice has long-lasting effects on open-field behavior dependent on mouse strain and age. Here we further investigated the impact of genotype and age on tyrosine hydroxylase (TH) loss and dopamine (DA) metabolism due to a high binge dose of Meth (4 × 5 mg/kg × 2 hours × 2 days). Administration of high dose Meth or saline (Sal) to adolescent (PND 40) and adult (PND 80) C57BL/6 (B6), DBA/2 (DBA), and 129S6SvEv/Tac (129) mice wa...

  6. Surface Weather Observations Hourly

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Standard hourly observations taken at Weather Bureau/National Weather Service offices and airports throughout the United States. Hourly observations began during...

  7. Does binge drinking during early pregnancy increase the risk of psychomotor deficits?

    DEFF Research Database (Denmark)

    Kesmodel, Ulrik Schiøler; Bay, Bjørn; Wimberley, Theresa;

    2013-01-01

    BACKGROUND: The potential effects of binge drinking during pregnancy on child motor function have only been assessed in a few, small studies. We aimed to examine the effects of binge alcohol consumption during early pregnancy, including number of binge episodes and timing of binge drinking, on ch...

  8. Cracking the Credit Hour

    Science.gov (United States)

    Laitinen, Amy

    2012-01-01

    The basic currency of higher education--the credit hour--represents the root of many problems plaguing America's higher education system: the practice of measuring time rather than learning. "Cracking the Credit Hour" traces the history of this time-based unit, from the days of Andrew Carnegie to recent federal efforts to define a credit hour. If…

  9. Forecasting Credit Hours.

    Science.gov (United States)

    Bivin, David; Rooney, Patrick Michael

    1999-01-01

    This study used Tobit analysis to estimate retention probabilities and credit hours at two universities. Tobit was judged as appropriate for this problem because it recognizes the lower bound of zero on credit hours and incorporates this bound into parameter estimates and forecasts. Models are estimated for credit hours in a single year and…

  10. Correlation of 2 hour, 4 hour, 8 hour and 12 hour urine protein with 24 hour urinary protein in preeclampsia.

    Directory of Open Access Journals (Sweden)

    Savita Rani Singhal

    2014-09-01

    Full Text Available To find shortest and reliable time period of urine collection for determination of proteinuria.It is a prospective study carried out on 125 pregnant women with preeclampsia after 20 weeks of gestation having urine albumin >1 using dipstick test. Urine was collected in five different time intervals in colors labeled containers with the assistance of nursing staff; the total collection time was 24 hours. Total urine protein of two-hour, four-hour, eight-hour, 12-hour and 24-hour urine was measured and compared with 24-hour collection. Data was analyzed using the Pearson correlation coefficient.There was significant correlation (p value < 0.01 in two, four, eight and 12-hour urine protein with 24-urine protein, with correlation coefficient of 0.97, 0.97, 0.96 and 0.97, respectively. When a cut off value of 25 mg, 50 mg. 100 mg, and 150 mg for urine protein were used for 2-hour, 4-hours, 8-hour and 12-hour urine collection, a sensitivity of 92.45%, 95.28%, 91.51%, and 96.23% and a specificity of 68.42%, 94.74%, 84.21% and 84.21% were obtained, respectively.Two-hour urine proteins can be used for assessment of proteinuria in preeclampsia instead of gold standard 24-hour urine collection for early diagnosis and better patient compliance.

  11. Baclofen reduces fat intake under binge-type conditions

    OpenAIRE

    Buda-Levin, Ariel; Wojnicki, Francis H. E.; Corwin, Rebecca L.

    2005-01-01

    The GABA-B agonist baclofen reduces drug self-administration in rats and has shown promise clinically in the treatment of substance abuse. Baclofen generally does not reduce food intake in non-binge feeding protocols. In this study, baclofen was tested in a fat-binge protocol. Thirty male rats were divided into three groups (B: binge; FM: fat-matched; C: chow). B received a bowl of vegetable shortening for 2 h on Monday, Wednesday, and Friday (MWF) and continuous access to powdered chow (regu...

  12. Neurobiological features of binge eating disorder.

    Science.gov (United States)

    Balodis, Iris M; Grilo, Carlos M; Potenza, Marc N

    2015-12-01

    Biobehavioral features associated with binge-eating disorder (BED) have been investigated; however, few systematic reviews to date have described neuroimaging findings from studies of BED. Emerging functional and structural studies support BED as having unique and overlapping neural features as compared with other disorders. Neuroimaging studies provide evidence linking heightened responses to palatable food cues with prefrontal areas, particularly the orbitofrontal cortex (OFC), with specific relationships to hunger and reward-sensitivity measures. While few studies to date have investigated non-food-cue responses; these suggest a generalized hypofunctioning in frontostriatal areas during reward and inhibitory control processes. Early studies applying neuroimaging to treatment efforts suggest that targeting neural function underlying motivational processes may prove important in the treatment of BED. PMID:26530404

  13. Understanding Eating Disorders, Anorexia, Bulimia, and Binge-Eating

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues Understanding Eating Disorders Past Issues / Spring 2008 Table of Contents For ... this page please turn Javascript on. Photo: iStock Eating disorders, such as anorexia nervosa, bulimia nervosa, and binge ...

  14. Determinants for binge drinking among adolescents in Denmark

    DEFF Research Database (Denmark)

    Pedersen, Maria; Kragh Andersen, Per; Sabroe, Svend

    2014-01-01

    Background and Objective: Binge drinking is a relatively common behavior among adolescents in Denmark. The aim of this study is to assess whether peer alcohol drinking, mothers’ and fathers’ attitudes toward alcohol drinking, and the adolescents’ own financial situations (e.g., the presence of...... pocket money) predict binge drinking among adolescents in Denmark. Methods: This study is based on the Danish data from the European School Survey Project on Alcohol and Other Drugs, which took place in 2011. This cross-sectional survey obtained data from 2765 adolescents who were in grade 9 in Denmark...... at that time. Logistic regression was used to assess the association between the outcome variable of binge drinking and the exposure variables of alcohol-drinking peers, pocket money, and mother’s/father’s approval of intoxication. Results: The risk of binge drinking increased with the number of...

  15. Binge Drinking and Occupation, North Dakota, 2004–2005

    Directory of Open Access Journals (Sweden)

    Dwayne W. Jarman, DVM, MPH

    2007-10-01

    Full Text Available IntroductionBinge drinking is a leading cause of preventable death and results in employee absenteeism and lost productivity. Knowledge about the prevalence of binge drinking among employees of different occupations is limited.MethodsWe assessed the prevalence of binge drinking (i.e., consuming five or more drinks per occasion during the previous 30 days by primary occupation using data from the 2004–2005 North Dakota Behavioral Risk Factor Surveillance System. We used logistic regression to assess the association between binge drinking and primary occupation.ResultsOverall, 24.1% (95% confidence interval [CI], 22.5–25.7 of North Dakota workers reported binge drinking. The prevalence was highest among farm or ranch employees (45.3%; 95% CI, 28.3–63.4, food or drink servers (33.4%; 95% CI, 23.9–44.4, and farm or ranch owners (32.5%; 95% CI, 26.3–39.4. The prevalence was lowest among health care workers (13.2%; 95% CI, 10.3–16.8. Compared with health care workers, the adjusted odds of binge drinking were highest among farm or ranch employees (adjusted odds ratio [AOR], 2.2; 95% CI, 0.9–5.5, food or drink servers (AOR, 2.1; 95% CI, 1.1–4.0, and farm or ranch owners (AOR, 1.7; 95% CI, 1.1–2.6. Health insurance coverage was lowest among employees in occupations with the highest prevalence of binge drinking.ConclusionWe found occupational differences in the prevalence of binge drinking among employees in North Dakota. Many occupational categories had a high prevalence of binge drinking. We recommend the implementation of both employer-sponsored and population-based interventions to reduce binge drinking among North Dakota workers, particularly because employees in occupations with the highest rates of binge drinking had the lowest rates of health insurance coverage.

  16. Effects of milnacipran on binge eating – a pilot study

    OpenAIRE

    Noma, Shun’ichi; Uwatoko, Teruhisa; Yamamoto, Haruka; Hayashi, Takuji

    2008-01-01

    Selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors are effective in the treatment of bulimia nervosa. There have been relatively few studies of the efficacy of specific serotonin and norepinephrine reuptake inhibitors in the treatment of eating disorders. Twenty-five outpatients with binge eating episodes, diagnosed as anorexia nervosa, binge-eating/purging type, bulimia nervosa/purging type, or bulimia nervosa/non-purging type, were treated with milnacip...

  17. Daily variations in cortisol levels and binge eating disorder.

    Science.gov (United States)

    Sitton, Sarah; Porn, Patricia M; Shaeffer, Stephanie

    2002-12-01

    Morning and afternoon levels of cortisol for 73 volunteers (67 women and 6 men) were compared in relation to their Binge Eating Disorder scores, Body Mass Indexes, and self-reports of mood and hunger. Cortisol level was not significantly correlated with binge eating or mood or hunger for either time period. However, it was inversely related to body mass, with lower cortisol levels associated with greater body mass.

  18. Binge Drinking – Nationwide Problem, Local Solutions

    Centers for Disease Control (CDC) Podcasts

    2012-01-03

    This podcast is based on the January 2012 CDC Vital Signs report. One in six adults binge drinks about four times a month. It's a problem nationwide but community-based strategies, such as reducing access to alcohol and increasing the price, can prevent binge drinking.  Created: 1/3/2012 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/3/2012.

  19. Systemisk/Narrativ gruppebehandling af Binge Eating Disorder

    DEFF Research Database (Denmark)

    Schousboe, Birgitte Hartvig

    2010-01-01

    Artiklen beskriver gruppeterapi på systemisk/narrativt grundlag til patienter med Binge Eating Disorder (BED). Den beskriver, hvordan en problemmættet historie omkring BED-gruppen blev dekonstrueret ved at ændre behandlingens udformning og eksperimentere med socialkonstruktionistiske ideer og......, hvilket har fremmet konsolideringen af foretrukne historier i gruppens refleksioner og styrket terapeuternes evne til at facilitere processen. Nøgleord: Binge Eating Disorder, systemisk narrativ terapi, grupppe...

  20. Preference for Safe Over Risky Options in Binge Eating.

    Science.gov (United States)

    Neveu, Rémi; Fouragnan, Elsa; Barsumian, Franck; Carrier, Edouard; Lai, Massimo; Nicolas, Alain; Neveu, Dorine; Coricelli, Giorgio

    2016-01-01

    Binge eating has been usually viewed as a loss of control and an impulsive behavior. But, little is known about the actual behavior of binging patients (prevalently women) in terms of basic decision-making under risk or under uncertainty. In healthy women, stressful cues bias behavior for safer options, raising the question of whether food cues that are perceived as threatening by binging patients may modulate patients' behaviors towards safer options. A cross-sectional study was conducted with binging patients (20 bulimia nervosa (BN) and 23 anorexia nervosa binging (ANB) patients) and two control groups (22 non-binging restrictive (ANR) anorexia nervosa patients and 20 healthy participants), without any concomitant impulsive disorder. We assessed decisions under risk with a gambling task with known probabilities and decisions under uncertainty with the balloon analog risk taking task (BART) with unknown probabilities of winning, in three cued-conditions including neutral, binge food and stressful cues. In the gambling task, binging and ANR patients adopted similar safer attitudes and coherently elicited a higher aversion to losses when primed by food as compared to neutral cues. This held true for BN and ANR patients in the BART. After controlling for anxiety level, these safer attitudes in the food condition were similar to the ones under stress. In the BART, ANB patients exhibited a higher variability in their choices in the food compared to neutral condition. This higher variability was associated with higher difficulties to discard irrelevant information. All these results suggest that decision-making under risk and under uncertainty is not fundamentally altered in all these patients. PMID:27065829

  1. Preference for safe over risky options in binge eating

    Directory of Open Access Journals (Sweden)

    Rémi eNeveu

    2016-03-01

    Full Text Available Background: Binge eating has been usually viewed as a preference for risky over safe appetitive rewards although this view has been drawn without manipulating stressing-inducing food cues. In healthy women, stressful cues bias behavior for safer options, raising the question of whether food cues modulate binging patients’ behaviors towards safer options.Method: A cross-sectional study was conducted with binging patients (20 bulimia nervosa (BN and 23 binging anorexia nervosa (ANB patients and two control groups (22 non-binging restrictive (ANR anorexia nervosa patients and 20 healthy participants, without any concomitant impulsive disorder. We assessed decisions under risk with a gambling task with known probabilities and decisions under uncertainty with the balloon analog risk taking task (BART with unknown probabilities of winning, in three cued-conditions including neutral, binge food and stressful cues.Results: In the gambling task, binging patients and ANR patients adopted similar safer attitudes and coherently elicited a higher aversion to losses when primed by food as compared to neutral cues. This differential behavior was also observed in the BART in BN and ANR patients only, aligning with the behavior of healthy controls when primed with stressful cues. In ANB patients, similar safer behaviors were observed in food and neutral conditions in the BART but with a higher variability in their choices in food condition. This higher variability was associated with higher difficulties to discard irrelevant information. Conclusion: Decision making under risk and under uncertainty is not fundamentally altered in binging patients but might be disturbed by a concomitant task.

  2. Daily variations in cortisol levels and binge eating disorder.

    Science.gov (United States)

    Sitton, Sarah; Porn, Patricia M; Shaeffer, Stephanie

    2002-12-01

    Morning and afternoon levels of cortisol for 73 volunteers (67 women and 6 men) were compared in relation to their Binge Eating Disorder scores, Body Mass Indexes, and self-reports of mood and hunger. Cortisol level was not significantly correlated with binge eating or mood or hunger for either time period. However, it was inversely related to body mass, with lower cortisol levels associated with greater body mass. PMID:12530732

  3. [Obesity, alexithymia, psychopathology and binge eating: a comparative study of 40 obese patients and 32 controls].

    Science.gov (United States)

    De Chouly De Lenclave, M B; Florequin, C; Bailly, D

    2001-01-01

    Alexithymia may be considered as a personality feature characterized by poorness of imaginary life, speech focused on actual facts and physical sensations, general inaccuracy in or paucity of the words used to express emotions, and recourse to acting out to avoid intrapsychic conflicts. The possible link between alexithymia and psychosomatic or psychopathological disorders is now well documented. In particular, studies suggested that alexithymia may be frequently observed in obese or bulimic patients. This study was designed to investigate the link between obesity and alexithymia according to the presence or not of binge eating problems; 40 obese female patients (BMI > or = 27.3) seeking obesity treatment and 32 normal weight women used as controls were included in the study. In the obese group, 11 patients (27.5%) exhibited binge-eating disorder according to the DSM IV criteria. Alexithymia was assessed using the Toronto Alexithymia Scale (TAS), and past and current mental disorders were assessed by means of the Structured Clinical Interview for DSM III-R (SCID). In addition, current depression was assessed using the Beck Depression Inventory (BDI). The mean TAS score was found significantly higher in obese patients than in controls (72.6 +/- 11.8 vs 65.2 +/- 9.3, respectively; p or = 74) was found significantly more frequent in obese patients than in controls (52.5% vs 21.8%, respectively; p eating disorder. Current major depression was also found significantly more frequent in obese patients than in controls (15% vs 0%, respectively; p eating disorder showed that only past major depression was found significantly more frequent in those with binge-eating disorder (81.8% vs 10.3%, respectively; p eating disorder (18.5 +/- 11.7 vs 9.8 +/- 5.9, respectively; p or = 74: low educational level (odds ratio: 3.56), past and/or current major depression (odds ratio: 2.77), and BDI score > or = 8 (odds ratio: 2.18). Obesity in itself had no significant effect on TAS scores

  4. Alcohol Use and Binge Drinking Among Women of Childbearing Age: United States, 2011-2013

    Science.gov (United States)

    ... and Mortality Weekly Report ( MMWR ) MMWR Share Compartir Alcohol Use and Binge Drinking Among Women of Childbearing ... 44 years (N = 198,098) who reported any alcohol use or binge drinking, † by selected characteristics — Behavioral ...

  5. Binge drinking, depression, and electrocortical responses to emotional images.

    Science.gov (United States)

    Connell, Arin M; Patton, Emily; McKillop, Hannah

    2015-09-01

    Binge drinking and depression are highly prevalent, associated with cognitive and affective impairments, and frequently co-occur. Yet little research has examined their joint relations with such processing impairment. The current study examines the relation between symptoms of depression, binge drinking, and the magnitude of early (early posterior negativity, EPN) and later (P3 and late positive potential, LPP) visual processing components of affectively negative, positive, and neutral visual stimuli. Participants included 42 undergraduate students recruited on the basis of depressive symptoms. Results of repeated measures analyses of variance (ANOVAs; Depression × Binge × Emotion × Laterality) showed that binge drinkers exhibited lower LPP amplitudes for negative images, compared with nonbinge drinkers, regardless of depression, consistent with motivational models of alcohol abuse. Otherwise, differences across depressed and nondepressed groups were largest among binge drinkers, including a pattern of stronger early attentional engagement (EPN) to negative and neutral images, but decreased later processing (P3 and LPP) across all emotional categories, consistent with a vigilance-avoidance response pattern. PMID:25915691

  6. N-acetylcysteine decreases binge eating in a rodent model.

    Science.gov (United States)

    Hurley, M M; Resch, J M; Maunze, B; Frenkel, M M; Baker, D A; Choi, S

    2016-07-01

    Binge-eating behavior involves rapid consumption of highly palatable foods leading to increased weight gain. Feeding in binge disorders resembles other compulsive behaviors, many of which are responsive to N-acetylcysteine (NAC), which is a cysteine prodrug often used to promote non-vesicular glutamate release by a cystine-glutamate antiporter. To examine the potential for NAC to alter a form of compulsive eating, we examined the impact of NAC on binge eating in a rodent model. Specifically, we monitored consumption of standard chow and a high-fat, high carbohydrate western diet (WD) in a rodent limited-access binge paradigm. Before each session, rats received either a systemic or intraventricular injection of NAC. Both systemic and central administration of NAC resulted in significant reductions of binge eating the WD without decreasing standard chow consumption. The reduction in WD was not attributable to general malaise as NAC did not produce condition taste aversion. These results are consistent with the clinical evidence of NAC to reduce or reverse compulsive behaviors, such as, drug addiction, skin picking and hair pulling. PMID:26975440

  7. Pharmacological Treatment of Binge Eating Disorder: Update Review and Synthesis

    Science.gov (United States)

    Reas, Deborah L.; Grilo, Carlos M.

    2015-01-01

    Introduction Binge-eating disorder (BED), a formal eating-disorder diagnosis in the DSM-5, is characterized by recurrent binge-eating, marked distress about binge-eating, and the absence of extreme weight compensatory behaviors. BED is more prevalent than other eating-disorders, with broader distribution across age, sex, and ethnic/racial groups, and is associated strongly with obesity and heightened risk for psychiatric/medical comorbidities. Areas Covered This article provides an overview of pharmacotherapy for BED with a focus on III randomized controlled trials (RCTs). The search with minimal methodological inclusion requirements yielded 22 RCTs investigating several different medication classes; most were pharmacotherapy-only trials with eight trials testing combination approaches with psychological-behavioral methods. Expert Opinion The evidence base regarding pharmacotherapy for BED remains limited, although this year the FDA approved the first medication (i.e., lisdexamfetamine dimesylate; LDX) specifically for moderate-to-severe BED. Data from RCTs suggests certain medications are superior to placebo for reducing binge-eating over the short-term; almost no data exist regarding longer-term effects of pharmacotherapy for BED. Except for topiramate, which significantly reduces both binge-eating and weight, tested medications yield minimal weight loss and LDX is not indicated for weight loss. Psychological-behavioral and combination approaches with certain medications yield superior outcomes to pharmacotherapy-only acutely and over longer-term follow-up. PMID:26044518

  8. Does the Interpersonal Model Generalize to Obesity Without Binge Eating?

    Science.gov (United States)

    Lo Coco, Gianluca; Sutton, Rachel; Tasca, Giorgio A; Salerno, Laura; Oieni, Veronica; Compare, Angelo

    2016-09-01

    The interpersonal model has been validated for binge eating disorder (BED), but it is not yet known if the model applies to individuals who are obese but who do not binge eat. The goal of this study was to compare the validity of the interpersonal model in those with BED versus those with obesity, and normal weight samples. Data from a sample of 93 treatment-seeking women diagnosed with BED, 186 women who were obese without BED, and 100 controls who were normal weight were examined for indirect effects of interpersonal problems on binge eating psychopathology mediated through negative affect. Findings demonstrated the mediating role of negative affect for those with BED and those who were obese without BED. Testing a reverse model suggested that the interpersonal model is specific for BED but that this model may not be specific for those without BED. This is the first study to find support for the interpersonal model in a sample of women with obesity but who do not binge. However, negative affect likely plays a more complex role in determining overeating in those with obesity but who do not binge. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association. PMID:27383030

  9. Does the Interpersonal Model Generalize to Obesity Without Binge Eating?

    Science.gov (United States)

    Lo Coco, Gianluca; Sutton, Rachel; Tasca, Giorgio A; Salerno, Laura; Oieni, Veronica; Compare, Angelo

    2016-09-01

    The interpersonal model has been validated for binge eating disorder (BED), but it is not yet known if the model applies to individuals who are obese but who do not binge eat. The goal of this study was to compare the validity of the interpersonal model in those with BED versus those with obesity, and normal weight samples. Data from a sample of 93 treatment-seeking women diagnosed with BED, 186 women who were obese without BED, and 100 controls who were normal weight were examined for indirect effects of interpersonal problems on binge eating psychopathology mediated through negative affect. Findings demonstrated the mediating role of negative affect for those with BED and those who were obese without BED. Testing a reverse model suggested that the interpersonal model is specific for BED but that this model may not be specific for those without BED. This is the first study to find support for the interpersonal model in a sample of women with obesity but who do not binge. However, negative affect likely plays a more complex role in determining overeating in those with obesity but who do not binge. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

  10. Binge Eating Proneness Emerges during Puberty in Female Rats: A Longitudinal Study

    OpenAIRE

    Klump, Kelly L.; Suisman, Jessica L.; Culbert, Kristen M.; Kashy, Deborah A.; Sisk, Cheryl L.

    2011-01-01

    Puberty is a critical risk period for binge eating and eating disorders characterized by binge eating. Previous research focused almost entirely on psychosocial risk factors during puberty to the relative exclusion of biological influences. The current study addressed this gap by examining the emergence of binge eating during puberty in a rat model. We predicted that there would be minimal differences in binge eating proneness during pre-early puberty, but significant differences would emerge...

  11. The Perspective Theory of Zong Bing in the 5th Century of China

    Institute of Scientific and Technical Information of China (English)

    LiuKeming; ZuoHongshan

    2003-01-01

    A brief historical introduction of researches on perspective in ancient China is presented,this paper studied and discussed the perspective theory or Zong Bing (宗炳) in the 5th century of China, including Zong Bing and this An introduction to Landscape Painting, and its mathematical basis, drawing ideas of Zong Bing as well.

  12. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice

    Science.gov (United States)

    Binge eating afflicts approximately 5% of US adults, though effective treatments are limited. Here, we showed that estrogen replacement substantially suppresses binge-like eating behavior in ovariectomized female mice. Estrogen-dependent inhibition of binge-like eating was blocked in female mice spe...

  13. Binge Eating Disorder and Body Uneasiness

    Directory of Open Access Journals (Sweden)

    Massimo Cuzzolaro

    2008-12-01

    Full Text Available Debate continues regarding the nosological status of binge eating disorder (BED and the specific diagnostic criteria, including whether, like anorexia nervosa and bulimia nervosa, it should be characterized by body image disturbances in addition to abnormal eating behaviour. The aims of this article are: a to concisely review the main points of the literature that has developed on diagnosis and treatment (especially pharmacological of BED and b to present the results of an original research on body image in obese patients with BED. The study was aimed to verify the following hypothesis: in persons with obesity, BED is associated with greater body uneasiness independently of some possible modulating factors. We studied a clinical sample of 159 (89 females and 70 males adult obese patients who fulfilled DSM-IV-TR diagnostic criteria for BED matched to 159 non-BED obese patients for gender, ethnicity, BMI class, age, weight, stature, onset age of obesity, education level, and marital status. We used the Body Uneasiness Test (BUT, a valuable multidimensional tool for the clinical assessment of body uneasiness in subjects suffering from eating disorders and/or obesity. Obese patients with BED reported higher scores than non-BED patients in the General Severity Index (BUT-A GSI and in every BUT-A subscale. All differences were statistically significant in both sexes. As expected women obtained higher scores than men. According to some other studies, our findings suggest that a negative body image should be included among diagnostic criteria for BED. Consequently, treatment should be focused not simply on eating behaviour and outcome studies should evaluate changes of body image as well.

  14. Binge Drinking Among Women and Girls PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2013-01-08

    This 60 second public service announcement is based on the January 2013 CDC Vital Signs report, which presents information about binge drinking among women and girls. Binge drinking is defined for women as four or more drinks in a short period of time. It puts women and girls at greater risk for breast cancer, sexual assault, heart disease, and unintended pregnancy.  Created: 1/8/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/8/2013.

  15. Applicability of the dual pathway model in normal and overweight binge eaters.

    Science.gov (United States)

    Welsh, Danielle M; King, Ross M

    2016-09-01

    Binge eating is a significant problem in both eating disordered and community populations alike. Extensive support exists for the dual pathway model of binge eating in both adolescent and adult clinical and nonclinical populations. However, the restrained eating pathway to binge eating in particular has failed to be confirmed in some studies. In particular, the dual pathway model may not be applicable to overweight binge eaters. The current study examined the applicability of the dual pathway model in a sample of healthy and overweight binge eaters. A total of 260 (115 healthy weight; 145 overweight or obese) adult binge eaters completed an online survey. Mediation analyses indicated support for both the dietary restraint and negative affect pathways in the healthy weight sample but only the latter pathway was supported in the overweight sample. Therefore, the full dual pathway model may only be applicable to healthy weight binge eaters. PMID:27479739

  16. New gate opening hours

    CERN Multimedia

    GS Department

    2009-01-01

    Please note the new opening hours of the gates as well as the intersites tunnel from the 19 May 2009: GATE A 7h - 19h GATE B 24h/24 GATE C 7h - 9h\t17h - 19h GATE D 8h - 12h\t13h - 16h GATE E 7h - 9h\t17h - 19h Prévessin 24h/24 The intersites tunnel will be opened from 7h30 to 18h non stop. GS-SEM Group Infrastructure and General Services Department

  17. Eleventh Hour Security+

    CERN Document Server

    Dubrawsky, Ido

    2009-01-01

    This book will focus on just the essentials needed to pass the Security+ certification exam. It will be filled with critical information in a way that will be easy to remember and use for your quickly approaching exam. It will focus on the main objectives of the exam and include the following pedagogy for ease of use in those final hours. The book will include:. •Exam Objectives – Fast Track Review. •Key words/definitions. •Five Toughest questions and their answers. •Exam Warnings – What to pay attention to

  18. Eleventh Hour Linux+

    CERN Document Server

    Speake, Graham; Happel, Chris; Lillard, Terrence V

    2009-01-01

    The 11th Hour Linux+ Study Guide is keyed to the XK0-003 revision of the CompTIA Linux+exam. This book is streamlined to include only core certification information and is presented for ease of last-minute studying. Main objectives of the exam are covered with key concepts highlighted. ..: ..; Fast Facts quickly review fundamentals ..; Exam Warnings highlight particularly tough sections of the exam ..; Crunch Time sidebars point out key concepts to remember ..; Did You Know? sidebars cover sometimes forgotten details ..; Top Five Toughest Questions and answers help you to prepare .. The 11th H

  19. Bingeing, Purging, and Estimates of Parental Attitudes regarding Female Achievement.

    Science.gov (United States)

    Silverstein, Brett; And Others

    1988-01-01

    Studies the relationship between perceived parental attitudes about female achievement and bingeing and purging. Surveys 326 female college students. Concludes that some eating disorders are related to feelings that being female is a disadvantage in some areas of intellectual/professional achievement. (FMW)

  20. Mesolimbic dopamine and its neuromodulators in obesity and binge eating.

    Science.gov (United States)

    Naef, Lindsay; Pitman, Kimberley A; Borgland, Stephanie L

    2015-12-01

    Obesity has reached epidemic prevalence, and much research has focused on homeostatic and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic circuitry, including dopamine neurons of the ventral tegmental area (VTA), is a key substrate for nonhomeostatic feeding. The goal of the present review is to compare changes in mesolimbic dopamine function in human obesity with diet-induced obesity in rodents. Additionally, we will review the literature to determine if dopamine signaling is altered with binge eating disorder in humans or binge eating modeled in rodents. Finally, we assess modulation of dopamine neurons by neuropeptides and peripheral peptidergic signals that occur with obesity or binge eating. We find that while decreased dopamine concentration is observed with obesity, there is inconsistency outside the human literature on the relationship between striatal D2 receptor expression and obesity. Finally, few studies have explored how orexigenic or anorexigenic peptides modulate dopamine neuronal activity or striatal dopamine in obese models. However, ghrelin modulation of dopamine neurons may be an important factor for driving binge feeding in rodents.

  1. Forskningsrapport: Samskabelsesparathed i Ringkøbing-Skjern Kommune, 2016

    DEFF Research Database (Denmark)

    Pedersen-Ulrich, Jens; Kjeldsen, Lena

    2016-01-01

    Forskningsrapporten præsenterer resultater af en spørgeskemaundersøgelse gennemført i Ringkøbing-Skjern Kommune i 2016. Undersøgelsen måler kommunens samskabelsesparathed i de enkelte fag- og stabsområder og er baseret på en samskabelsestypologi, der indeholder fire tilgange til samskabelse: styret...

  2. Quit Binging (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2015-01-15

    Too many people are overindulging in alcohol and putting themselves at risk for death from alcohol poisoning. In this podcast, Dr. Dafna Kanny discusses the dangers of binge drinking, including alcohol poisoning death.  Created: 1/15/2015 by MMWR.   Date Released: 1/15/2015.

  3. Heterogeneity Moderates Treatment Response among Patients with Binge Eating Disorder

    Science.gov (United States)

    Sysko, Robyn; Hildebrandt, Tom; Wilson, G. Terence; Wilfley, Denise E.; Agras, W. Stewart

    2010-01-01

    Objective: The purpose of the study was to explore heterogeneity and differential treatment outcome among a sample of patients with binge eating disorder (BED). Method: A latent class analysis was conducted with 205 treatment-seeking, overweight or obese individuals with BED randomized to interpersonal psychotherapy (IPT), behavioral weight loss…

  4. Binge Eating Disorder: A Review of a New "DSM" Diagnosis

    Science.gov (United States)

    Myers, Laura L.; Wiman, Allison M.

    2014-01-01

    In 1994, binge eating disorder (BED) was introduced as a disorder requiring further study in the "American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders", fourth edition ("DSM-IV"). It is now listed as a distinct eating disorder in the "DSM-5", along with bulimia nervosa and…

  5. Cognitive processes in alcohol binges: A review and research agenda

    NARCIS (Netherlands)

    M. Field; T. Schoenmakers; R.W. Wiers

    2008-01-01

    Alcohol abuse is associated with a cluster of long-term changes in cognitive processes, as predicted by contemporary models of addiction. In this paper we review evidence which suggests that similar changes may occur during an alcohol binge, and as such they may play an important role in explaining

  6. Cognitive processes in alcohol binges : a review and research agenda

    NARCIS (Netherlands)

    Field, M.; Schoenmakers, T.; Wiers, R.W.H.J.

    2008-01-01

    Alcohol abuse is associated with a cluster of long-term changes in cognitive processes, as predicted by contemporary models of addiction. In this paper we review evidence which suggests that similar changes may occur during an alcohol binge, and as such they may play an important role in explaining

  7. Integrative Response Therapy for Binge Eating Disordspan>er

    Science.gov (United States)

    Robinson, Athena

    2013-01-01

    Binge eating disorder (BED), a chronic condition characterized by eating disorder psychopathology and physical and social disability, represents a significant public health problem. Guided self-help (GSH) treatments for BED appear promising and may be more readily disseminable to mental health care providers, accessible to patients, and…

  8. Effects of milnacipran on binge eating – a pilot study

    Directory of Open Access Journals (Sweden)

    Shun’ichi Noma

    2008-03-01

    Full Text Available Shun’ichi Noma1, Teruhisa Uwatoko1, Haruka Yamamoto2, Takuji Hayashi11Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Department of Psychiatry, Toyooka Hospital, Hyogo, JapanAbstract: Selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors are effective in the treatment of bulimia nervosa. There have been relatively few studies of the efficacy of specific serotonin and norepinephrine reuptake inhibitors in the treatment of eating disorders. Twenty-five outpatients with binge eating episodes, diagnosed as anorexia nervosa, binge-eating/purging type, bulimia nervosa/purging type, or bulimia nervosa/non-purging type, were treated with milnacipran and 20 patients completed the 8-week study. Symptom severity was evaluated using the Bulimic Investigatory Test, Edinburgh (BITE self-rating scale before administration of milnacipran and after 1, 4, and 8 weeks treatment. The scores improved after 8 weeks, especially drive to, and regret for, binge eating. Milnacipran was more effective in patients without purging and in younger patients, while there was no difference in the efficacy of milnacipran among subtypes of eating disorders.Keywords: milnacipran, specific serotonin and norepinephrine reuptake inhibitors, binge eating, vomiting, eating disorder, pharmacotherapy

  9. Mesolimbic dopamine and its neuromodulators in obesity and binge eating.

    Science.gov (United States)

    Naef, Lindsay; Pitman, Kimberley A; Borgland, Stephanie L

    2015-12-01

    Obesity has reached epidemic prevalence, and much research has focused on homeostatic and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic circuitry, including dopamine neurons of the ventral tegmental area (VTA), is a key substrate for nonhomeostatic feeding. The goal of the present review is to compare changes in mesolimbic dopamine function in human obesity with diet-induced obesity in rodents. Additionally, we will review the literature to determine if dopamine signaling is altered with binge eating disorder in humans or binge eating modeled in rodents. Finally, we assess modulation of dopamine neurons by neuropeptides and peripheral peptidergic signals that occur with obesity or binge eating. We find that while decreased dopamine concentration is observed with obesity, there is inconsistency outside the human literature on the relationship between striatal D2 receptor expression and obesity. Finally, few studies have explored how orexigenic or anorexigenic peptides modulate dopamine neuronal activity or striatal dopamine in obese models. However, ghrelin modulation of dopamine neurons may be an important factor for driving binge feeding in rodents. PMID:26514168

  10. Quantitative and qualitative assessment of university students' definitions of binge drinking.

    Science.gov (United States)

    Bonar, Erin E; Young, Kathleen M; Hoffmann, Erica; Gumber, Shinakee; Cummings, Jeremy P; Pavlick, Michelle; Rosenberg, Harold

    2012-06-01

    This study was designed to assess undergraduates' (N = 424) definitions of binge drinking and to evaluate whether the number of drinks they said comprise a binge varied as a function of beverage type, respondent gender, and respondent binge drinking status. When asked to designate the specific number of drinks that comprise a binge for each of four beverage types, students reported that the number of beers constituting a binge was significantly larger than the number of glasses of wine, shots of hard liquor, and servings of any combination of alcoholic beverage types; men reported that a larger number of drinks constitute a binge than did women; and those who had engaged in 3 or more binges in the past 2 weeks reported that more drinks comprise a binge than those who had binged less often. Responses to an open-ended question asking their definition of a binge revealed that students sometimes characterize a binge in terms of motivations for and unhealthy consequences of drinking, in addition to defining a binge as comprising consumption of a large amount of alcohol in a limited (though often unspecified) time period. Furthermore, students attributed their open-ended definitions of binge drinking to informal sources of information and observation of others' drinking almost as often as they did to school-based or media-based sources. This suggests that educators might look for innovative ways to use both formal and informal social networking, and video illustrations of restrained drinking, as ways to influence young people's views of binge drinking.

  11. Baclofen reduces fat intake under binge-type conditions.

    Science.gov (United States)

    Buda-Levin, Ariel; Wojnicki, Francis H E; Corwin, Rebecca L

    2005-09-15

    The GABA-B agonist baclofen reduces drug self-administration in rats and has shown promise clinically in the treatment of substance abuse. Baclofen generally does not reduce food intake in non-binge feeding protocols. In this study, baclofen was tested in a fat-binge protocol. Thirty male rats were divided into three groups (B: binge; FM: fat-matched; C: chow). B received a bowl of vegetable shortening for 2 h on Monday, Wednesday, and Friday (MWF) and continuous access to powdered chow (regular chow) in all phases. FM had continuous access to a regular chow+shortening mixture (FM chow) that provided the same proportion of shortening and regular chow that the B rats consumed in all phases. In addition, FM had the following: phase 1: no separate bowl of shortening; phase 2: 2-h MWF access to a separate bowl of shortening; phase 3, daily 2-h access to a separate bowl of shortening; C rats had continuous access to the regular chow in all phases. In addition, C had the following: phase 1: no separate bowl of shortening; phase 2: 2-h MWF access to a separate bowl of shortening; in phase 3, daily 2-h access to a separate bowl of shortening. Baclofen (1.0, 1.8 mg/kg, i.p.) reduced shortening intake regardless of access condition. Baclofen had no effect on, or stimulated, FM and regular chow intake. These results demonstrate that baclofen can reduce fat intake in rats under binge-type conditions. Furthermore, these results indicate that bingeing, as modeled in our protocol, is different from other forms of food intake and may share similarities with substance abuse. PMID:16140347

  12. FEWER HOURS MORE ACHIEVEMENTS

    Institute of Scientific and Technical Information of China (English)

    NingQuanxin; QiuLizhong

    2004-01-01

    The goal of this study is to improve instructional classes for “Extensive Reading”. We compare two approaches. The traditional method is based on the original procedure; the method we try is a “task-placemented” one. inspired by the method we try is a “task-placemented” one. inspired by the theory of “Tasks of Ascending Difficulty”.This paper provides a comparative evaluation of our experiments on Extensive Reading. Our aim is to resolve the logistical problem of heavy teaching loads and limited class hours, which often prevents English learners from fulfilling their study targets and our intended learning outcomes. In view of the experimental data,we have managed to establish a “feedback” to test the two hypotheses, and demonstrate that the new approach contributes to efficient acquisition of the information in the presented reading materials. Our study concludes with an interpretation of the function and merits of this approach.

  13. Geneva 24 Hours Swim

    CERN Multimedia

    2003-01-01

    The 18th edition of the Geneva 24 hours swim competition will take place at the Vernets Swimming Pool on the 4th and 5th of October. More information and the results of previous years are given at: http://www.carouge-natation.com/24_heures/home_24_heures.htm Last year, CERN obtained first position in the inter-company category with a total of 152.3 kms swam by 45 participants. We are counting on your support to repeat this excellent performance this year. For those who would like to train, the Livron swimming pool in Meyrin is open as from Monday the 8th September. For further information please do not hesitate to contact us. Gino de Bilio and Catherine Delamare

  14. Geneva 24 hours swim

    CERN Multimedia

    2003-01-01

    The 18th edition of the Geneva 24 hours swim competition will take place at the Vernets Swimming Pool on the 4th and 5th of October. More information and the results of previous years are given at: http://www.carouge-natation.com/24_heures/home_24_heures.htm Last year, CERN obtained first position in the inter-company category with a total of 152.3 kms swam by 45 participants. We are counting on your support to repeat this excellent performance this year. For those who would like to train, the Livron swimming pool in Meyrin is open as from Monday the 8th September. For further information please do not hesitate to contact us. Gino de Bilio and Catherine Delamare

  15. An empirical comparison of atypical bulimia nervosa and binge eating disorder

    Directory of Open Access Journals (Sweden)

    Fontenelle L.F.

    2005-01-01

    Full Text Available The International Classification of Diseases, 10th edition (ICD-10 defines atypical bulimia nervosa (ABN as an eating disorder that encompasses several different syndromes, including the DSM-IV binge eating disorder (BED. We investigated whether patients with BED can be differentiated clinically from patients with ABN who do not meet criteria for BED. Fifty-three obese patients were examined using the Structured Clinical Interview for DSM-IV and the ICD-10 criteria for eating disorders. All volunteers completed the Binge Eating Scale (BES, the Beck Depression Inventory, and the Symptom Checklist-90 (SCL-90. Individuals fulfilling criteria for both ABN and BED (N = 18, ABN without BED (N = 16, and obese controls (N = 19 were compared and contrasted. Patients with ABN and BED and patients with ABN without BED displayed similar levels of binge eating severity according to the BES (31.05 ± 7.7 and 30.05 ± 5.5, respectively, which were significantly higher than those found in the obese controls (18.32 ± 8.7; P < 0.001 and P < 0.001, respectively. When compared to patients with ABN and BED, patients with ABN without BED showed increased lifetime rates of agoraphobia (P = 0.02 and increased scores in the somatization (1.97 ± 0.85 vs 1.02 ± 0.68; P = 0.001, obsessive-compulsive (2.10 ± 1.03 vs 1.22 ± 0.88; P = 0.01, anxiety (1.70 ± 0.82 vs 1.02 ± 0.72; P = 0.02, anger (1.41 ± 1.03 vs 0.59 ± 0.54; P = 0.005 and psychoticism (1.49 ± 0.93 vs 0.75 ± 0.55; P = 0.01 dimensions of the SCL-90. The BED construct may represent a subgroup of ABN with less comorbities and associated symptoms.

  16. Psychosocial and metabolic function by smoking status in individuals with binge eating disorder and obesity.

    Science.gov (United States)

    Udo, Tomoko; White, Marney A; Barnes, Rachel D; Ivezaj, Valentina; Morgan, Peter; Masheb, Robin M; Grilo, Carlos M

    2016-02-01

    Individuals with binge eating disorder (BED) report smoking to control appetite and weight. Smoking in BED is associated with increased risk for comorbid psychiatric disorders, but its impact on psychosocial functioning and metabolic function has not been evaluated. Participants were 429 treatment-seeking adults (72.4% women; mean age 46.2±11.0years old) with BED comorbid with obesity. Participants were categorized into current smokers (n=66), former smokers (n=145), and never smokers (n=218). Smoking status was unrelated to most historical eating/weight variables and to current eating disorder psychopathology. Smoking status was associated with psychiatric, psychosocial, and metabolic functioning. Compared with never smokers, current smokers were more likely to meet lifetime diagnostic criteria for alcohol (OR=5.51 [95% CI=2.46-12.33]) and substance use disorders (OR=7.05 [95% CI=3.37-14.72]), poorer current physical quality of life, and increased risk for metabolic syndrome (OR=1.80 [95% CI=0.97-3.35]) and related metabolic risks (reduced HDL, elevated total cholesterol). On the other hand, the odds of meeting criteria for lifetime psychiatric comorbidity or metabolic abnormalities were not significantly greater in former smokers, relative to never smokers. Our findings suggest the importance of promoting smoking cessation in treatment-seeking patients with BED and obesity for its potential long-term implications for psychiatric and metabolic functioning.

  17. The role of anxiety in binge eating behavior: a critical examination of theory and empirical literature

    Directory of Open Access Journals (Sweden)

    Diane L. Rosenbaum

    2013-06-01

    Full Text Available The purpose of this manuscript is to expand the understanding of binge eating by reviewing the role of aspects of negative affect. Specifically, this paper will present evidence for further investigation of the bearing that anxiety may have in binge eating development and maintenance. A comprehensive review of the literature regarding the relation of binge eating and anxiety was performed. Valuable contributions have been made to the binge eating literature regarding some aspects of negative affect (i.e., depression; however, outside of bulimia nervosa studies, much of the theoretical and empirical binge eating research to date has not directly addressed the role of anxiety. Research supports expansion of investigations of negative emotionality and binge eating to include specific study of anxiety. Greater inclusivity and specificity in the unique contributions of various negative emotions may further the development of temporal models and intervention efforts.

  18. Do women give the same information on binge drinking during pregnancy when asked repeatedly?

    DEFF Research Database (Denmark)

    Strandberg-Larsen, Katrine; Andersen, Anne-Marie Nybo; Olsen, Jørn;

    2006-01-01

    OBJECTIVE: To study if pregnant women give the same answers to questions on frequency and timing of binge drinking when asked more than once during and after pregnancy. DESIGN: Cohort study.Setting:The Danish National Birth Cohort. SUBJECTS: The study is based on 76 307 pregnant women with repeated...... information on binge drinking during the early part of pregnancy and 8933 pregnant women with information on binge drinking during pregnancy weeks 30-36, obtained while pregnant and 6 months after delivery. RESULTS: More women reported binge drinking, if the interview took place close to the period...... in question. As the report of binge drinking was highest in the first of two interviews referring to the same period, as well as women who participated in the first interview in pregnancy week 12 or earlier reported more binge drinking compared to women who participated in the interview later in pregnancy...

  19. Translations of Sun Zi Bing Fa into English

    Institute of Scientific and Technical Information of China (English)

    Shang Lijuan

    2014-01-01

    This thesis is intended to introduce the English translation of Sun Zi Bing Fa, and carry on the preliminary discussion to what do the Chinese and foreign translators stress to about the translations of Sun Zi Bing Fa. At the very beginning, the thesis briefly makes a brief comment on the influence of Sun Zi Bing Fa on the ancient Chinese culture. It is known that the influences of the Confucianism and Taoism are profound to China, not only have they influenced the ideology, but also affect all aspects of the society. Sun Zi Bing Fa is an ancient Chinese military treatise. It is commonly known to be the definitive work on military strategy and tactics of its time. If anyone wants to have a deep understanding about Eastern military thinking, business tactics, legal strategy, all must begin from Sun Zi Bing Fa. This thesis makes a brief introduction about the English translations of Sun Zi Bing Fa, and some of the most influential versions of Sun Zi Bing Fa. The thesis also points out the different styles of each translation. The English translation of Sun Zi Bing Fa is a main part of the English translation of the Chinese Classics, and made great contributions to it. According to the analyses of this thesis, we make several proposes about the development of the translations of the Chinese Classics into English, and hope that it will benefit to the promotion of cultural exchange.%本文介绍了《孙子兵法》的英译情况,对中外译者关于先秦典籍的翻译的侧重进行了初步的探讨。文章首先简要介绍了《孙子兵法》在中国文化中的地位。《孙子兵法》对中国的影响深远,涉及社会生活的各个方面。《孙子兵法》是中国古代军事著作,是在军事战略和战术的权威著作。如果要深入理解东方的军事思路,商业策略,在很多问题上都必须回溯到《孙子兵法》。本文重点介绍了《孙子兵法》的英译情况。并对其中的重要译家和译本进行了

  20. Binge drinking: Burden of liver disease and beyond

    Institute of Scientific and Technical Information of China (English)

    Susana; Llerena; María; Teresa; Arias-Loste; Angela; Puente; Joaquín; Cabezas; Javier; Crespo; Emilio; Fábrega

    2015-01-01

    The consumption of alcoholic beverages is harmful to human health. In recent years, consumption patterns of alcoholic beverages have changed in our society, and binge drinking has generalized. It is considered to be a socio-sanitary problem with few known consequences in terms of individual and third-party social impacts(in the form of violence or traffic accidents) and its organic impact(affects the liver and other organs and systems, such as the nervous and cardiovascular systems) and represents an important financial burden due to its increasing economic impact. This review provides a global approach to binge drinking and emphasizes its epidemiological character, the effect of this type of consumption and the possible management of a problem with an increasing tendency in our society.

  1. Underage Binge Drinking Adolescents: Sociodemographic Profile and Utilization of Family Doctors

    OpenAIRE

    Fuller-Thomson, Esme; Matthew P. Sheridan; Sorichetti, Cathy; Mehta, Rukshan

    2013-01-01

    Context. Binge drinking (more than five drinks on one occasion) is a major public health problem among teenagers in the US, Canada, and Europe. Negative outcomes to binge drinking include alcohol related injuries and accidental death. Family physicians are the main point of contact between binging adolescents and the health care system. Design and Setting. This study was based on a secondary analysis of 6,607 respondents aged 15–17 from the regionally representative data acquired through the ...

  2. Explaining binge drinking among adolescent males using the Theory of Planned Behaviour

    OpenAIRE

    Dempster, Martin; G. Newell; Marley, John

    2005-01-01

    Binge drinking among adolescents in Northern Ireland is prevalent and has detrimental eff ects on public health. Health education interventions, based on valid explanatory models of health behaviour, are required to reduce binge drinking behaviour among adolescents. " is paper examines the utility of the " eory of Planned Behaviour in explaining binge drinking behaviour among adolescent males. Using questionnaire responses from 94 adolescent boys attending secondary schools in the Belfast are...

  3. Taussig-Bing Anomaly: From Original Description to the Current Era

    OpenAIRE

    Konstantinov, Igor E.

    2009-01-01

    Taussig-Bing anomaly is a rare congenital heart malformation that was first described in 1949 by Helen B. Taussig (1898–1986) and Richard J. Bing (1909–). Although substantial improvement has since been achieved in surgical results of the repair of the anomaly, management of the Taussig-Bing anomaly remains challenging. A history of the original description of the anomaly, the life stories of the individuals who first described it, and the current outcomes of its surgical management are revie...

  4. Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action

    OpenAIRE

    Lindtner, Claudia; Scherer, Thomas; Zielinski, Elizabeth; Filatova, Nika; Fasshauer, Martin; Tonks, Nicholas K.; Puchowicz, Michelle; Buettner, Christoph

    2013-01-01

    Individuals with a history of binge drinking have an increased risk of developing the metabolic syndrome and type 2 diabetes. Whether binge drinking impairs glucose homeostasis and insulin action is unknown. To test this, we treated Sprague-Dawley rats daily with alcohol (3 g/kg) for three consecutive days to simulate human binge drinking and found that these rats developed and exhibited insulin resistance even after blood alcohol concentrations had become undetectable. The animals were resis...

  5. The study of food addiction using animal models of binge eating☆

    OpenAIRE

    Avena, Nicole M.

    2010-01-01

    This review summarizes evidence of “food addiction” using animal models of binge eating. In our model of sucrose bingeing, behavioral components of addiction are demonstrated and related to neurochemical changes that also occur with addictive drugs. Evidence supports the hypothesis that rats can become dependent and “addicted” to sucrose. Results obtained when animals binge on other palatable foods, including a fat-rich food, are described and suggest that increased body weight can occur. How...

  6. Perceived expressed emotion in adolescents with binge-eating disorder

    OpenAIRE

    Schmidt, Ricarda; Tetzlaff, Anne; Hilbert, Anja

    2016-01-01

    A sizeable body of research has documented Expressed Emotion (EE) to predict clinical outcomes in various psychiatric disorders, including eating disorders. Patients’ perceptions of relative’s EE, however, were found to play an important role in the processing of EE. This study aimed to examine the level of perceived EE in adolescent binge-eating disorder (BED) and its impact on eating disorder psychopathology. Adolescents (12 – 20 years) seeking treatment for BED (n = 40) were compared to...

  7. Binge Drinking and Risky Sex among College Students

    OpenAIRE

    DeSimone, Jeff

    2010-01-01

    This study examines the relationship between binge drinking and sexual behavior in nationally representative data on age 18–24 four-year college students. For having sex, overall or without condoms, large and significant positive associations are eliminated upon holding constant proxies for time-invariant sexual activity and drinking preferences. However, strong relationships persist for sex with multiple recent partners, overall and without condoms, even controlling for substance use, risk a...

  8. Alexithymia, depression, anxiety and binge eating in obese women

    OpenAIRE

    Agnieszka Źak-Gołąb; Radosław Tomalski; Monika Bąk-Sosnowska; Michał Holecki; Piotr Kocełak; Magdalena Olszanecka-Glinianowicz; Jerzy Chudek; Barbara Zahorska-Markiewicz

    2013-01-01

    Background and Objectives: Alexithymia is a personality trait that may affect the development and course of obesity and effectiveness of treatment. The aim of the study is to assess the prevalence of alexithymia in obese women beginning a weight reduction program and determine the relationships between alexithymia and anxiety, depression, and binge eating. Methods: Obese women (n = 100; age 45 ± 13 yr) completed the following self-report inventories: Toronto Alexithymia Scale (TAS 26), Hospit...

  9. Binge Eating Disorder and Body Uneasiness

    OpenAIRE

    Massimo Cuzzolaro; Maurizio Bellini; Lorenzo Donini; Chiara Santomassimo

    2008-01-01

    Debate continues regarding the nosological status of binge eating disorder (BED) and the specific diagnostic criteria, including whether, like anorexia nervosa and bulimia nervosa, it should be characterized by body image disturbances in addition to abnormal eating behaviour. The aims of this article are: a) to concisely review the main points of the literature that has developed on diagnosis and treatment (especially pharmacological) of BED and b) to present the results of an original resear...

  10. Hourly Precipitation Data (HPD) Publication

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hourly Precipitation Data (HPD) Publication is archived and available from the National Climatic Data Center (NCDC). This publication contains hourly precipitation...

  11. Employment and hours of work

    OpenAIRE

    Kudoh, Noritaka; Sasaki, Masaru

    2009-01-01

    This paper develops a dynamic model of the labor market in which the degree of substitution between employment and hours of work is determined as part of a search equilibrium. Each firm chooses its demand for working hours and number of vacancies, and the earnings profile is determined by Nash bargaining. The earnings profile is generally nonlinear in hours of work, and defines the trade-off between employment and hours of work. Concave production technology induces firms to overemploy and, a...

  12. The neurobiological basis of binge-eating disorder.

    Science.gov (United States)

    Kessler, Robert M; Hutson, Peter H; Herman, Barry K; Potenza, Marc N

    2016-04-01

    Relatively little is known about the neuropathophysiology of binge-eating disorder (BED). Here, the evidence from neuroimaging, neurocognitive, genetics, and animal studies are reviewed to synthesize our current understanding of the pathophysiology of BED. Binge-eating disorder may be conceptualized as an impulsive/compulsive disorder, with altered reward sensitivity and food-related attentional biases. Neuroimaging studies suggest there are corticostriatal circuitry alterations in BED similar to those observed in substance abuse, including altered function of prefrontal, insular, and orbitofrontal cortices and the striatum. Human genetics and animal studies suggest that there are changes in neurotransmitter networks, including dopaminergic and opioidergic systems, associated with binge-eating behaviors. Overall, the current evidence suggests that BED may be related to maladaptation of the corticostriatal circuitry regulating motivation and impulse control similar to that found in other impulsive/compulsive disorders. Further studies are needed to understand the genetics of BED and how neurotransmitter activity and neurocircuitry function are altered in BED and how pharmacotherapies may influence these systems to reduce BED symptoms. PMID:26850211

  13. Therapeutic alliance and binge-eating outcomes in a group therapy context.

    Science.gov (United States)

    Tasca, Giorgio A; Compare, Angelo; Zarbo, Cristina; Brugnera, Agostino

    2016-07-01

    The therapeutic alliance in individual and group psychotherapy is associated with treatment outcomes for a variety of disorders. However, debate persists about the centrality of the alliance in determining positive outcomes. We examined the alliance-outcome relationship across 20 sessions of emotionally focused group therapy (EFGT) for binge-eating disorder (BED). We hypothesized that (1) previous session alliance increase will predict lower subsequent session binge eating level while controlling for previous session binge eating level; and (2) previous session binge eating decline will predict higher subsequent session alliance level while controlling previous session alliance level. Participants were 118 individuals with BED who received 20 sessions of EFGT in 8 groups. Levels of binge eating and therapeutic alliance to the therapist were measured weekly. Linear growth in alliance during group therapy was associated with reduced binge eating at 6 months' posttreatment. We also found that the group's and the individual's alliance scores and binge-eating episodes were significantly associated across treatment, suggesting a mutual influence of the group's and individual's experience of the alliance with the therapist. Regarding the first hypothesis, previous session alliance increase was significantly associated with lower subsequent session binge eating. Regarding the second hypothesis, previous session binge-eating decline was not significantly related to higher subsequent session alliance. The findings provide evidence in a group therapy context for a model in which alliance change influences subsequent symptom levels, but not the other way around. (PsycINFO Database Record PMID:27182894

  14. Examining the relationship between food thought suppression and binge eating disorder.

    Science.gov (United States)

    Barnes, Rachel D; Masheb, Robin M; White, Marney A; Grilo, Carlos M

    2013-10-01

    Food thought suppression, or purposely attempting to avoid thoughts of food, is related to a number of unwanted eating- and weight-related consequences, particularly in dieting and obese individuals. Little is known about the possible significance of food thought suppression in clinical samples, particularly obese patients who binge eat. This study examined food thought suppression in 150 obese patients seeking treatment for binge eating disorder (BED). Food thought suppression was not associated with binge eating frequency or body mass index but was significantly associated with higher current levels of eating disorder psychopathology and variables pertaining to obesity, dieting, and binge eating.

  15. Pharmacological interventions for binge eating: lessons from animal models, current treatments, and future directions.

    Science.gov (United States)

    Berner, Laura A; Bocarsly, Miriam E; Hoebel, Bartley G; Avena, Nicole M

    2011-01-01

    Binge eating behavior has been noted in some eating disorders as well as in obesity. The goal of this paper is to review current, non-serotonergic pharmaceutical approaches to treat binge eating. Further, using information derived from preclinical models, we discuss candidate neurotransmitter systems for study as targets for the treatment of binge eating. Dopaminergic circuits have been implicated in both laboratory animal models and human studies of binge eating, though existing medications specifically targeting the dopaminergic system have been found to have adverse side effects. Opioidergic and gamma-aminobutyric acid (GABA) systems also appear to be highly involved in aspects of binge eating; further, opioid antagonists, such as naloxone and naltrexone, and GABA agonists, such as baclofen, have all been shown to be effective in treating alcohol dependence and may be equally efficacious in attenuating binge eating. Preclinical evidence, and some clinical evidence, suggests that cannabinoid antagonism may also be useful in the treatment of binge eating, although the specific effect of antagonists, on binge consumption remains unclear. Overall, each of these neurotransmitter systems provides a promising avenue for new pharmacotherapy development for binge eating, and preclinical and human studies provide a strong rationale for the development of highly-selective drugs that target this neurocircuitry. PMID:21492094

  16. Change in binge eating and binge eating disorder associated with migration from Mexico to the U.S.

    Science.gov (United States)

    Swanson, Sonja A; Saito, Naomi; Borges, Guilherme; Benjet, Corina; Aguilar-Gaxiola, Sergio; Medina-Mora, Maria Elena; Breslau, Joshua

    2012-01-01

    Exposure to Western popular culture is hypothesized to increase risk for eating disorders. This study tests this hypothesis with respect to the proposed diagnosis of binge eating disorder (BED) in an epidemiological sample of people of Mexican origin in Mexico and the U.S. Data come from the Mexico National Comorbidity Survey, National Comorbidity Survey Replication, and National Latino and Asian American Survey (N = 2268). Diagnoses were assessed with the WMH-CIDI. Six groups were compared: Mexicans with no migrant family members, Mexicans with at least one migrant family member, Mexican return-migrants, Mexican-born migrants in the U.S., and two successive generations of Mexican-Americans in the U.S. The lifetime prevalence of BED was 1.6% in Mexico and 2.2% among Mexican-Americans. Compared with Mexicans in families with migrants, risk for BED was higher in US-born Mexican-Americans with two U.S.-born parents (aHR = 2.58, 95% CI 1.12-5.93). This effect was attenuated by 24% (aHR = 1.97, 95% CI 0.84-4.62) with adjustment for prior-onset depressive or anxiety disorder. Adjustment for prior-onset conduct disorder increased the magnitude of association (aHR = 2.75, 95% CI 1.22-6.20). A similar pattern was observed for binge eating. Among respondents reporting binge eating, onset in the U.S. (vs. Mexico) was not associated with prevalence of further eating disorder symptoms. Migration from Mexico to the U.S. is associated with an increased risk for BED that may be partially attributable to non-specific influences on internalizing disorders. Among respondents reporting binge eating in either country, similar levels of further symptoms were endorsed, suggesting some cross-cultural generalizability of criteria. PMID:22070904

  17. STS-72 Mission Insignia

    Science.gov (United States)

    1995-01-01

    The crew patch of STS-72 depicts the Space Shuttle Endeavour and some of the payloads on the flight. The Japanese satellite, Space Flyer Unit (SFU) is shown in a free-flying configuration with the solar array panels deployed. The inner gold border of the patch represents the SFU's distinct octagonal shape. Endeavour's rendezvous with and retrieval of SFU at an altitude of approximately 250 nautical miles. The Office of Aeronautics and Space Technology's (OAST) flyer satellite is shown just after release from the Remote Manipulator System (RMS). The OAST satellite was deployed at an altitude of 165 nautical miles. The payload bay contains equipment for the secondary payloads - the Shuttle Laser Altimeter (SLA) and the Shuttle Solar Backscatter Ultraviolet Instrument (SSBUV). There were two space walks planned to test hardware for assembly of the International Space Station. The stars represent the hometowns of the crew members in the United States and Japan.

  18. Differences in bingeing behavior and cocaine reward following intermittent access to sucrose, glucose or fructose solutions.

    Science.gov (United States)

    Rorabaugh, J M; Stratford, J M; Zahniser, N R

    2015-08-20

    Daily intermittent access to sugar solutions results in intense bouts of sugar intake (i.e. bingeing) in rats. Bingeing on sucrose, a disaccharide of glucose and fructose, has been associated with a "primed" mesolimbic dopamine (DA) pathway. Recent studies suggest glucose and fructose engage brain reward and energy-sensing mechanisms in opposing ways and may drive sucrose intake through unique neuronal circuits. Here, we examined in male Sprague-Dawley rats whether or not (1) intermittent access to isocaloric solutions of sucrose, glucose or fructose results in distinctive sugar-bingeing profiles and (2) previous sugar bingeing alters cocaine locomotor activation and/or reward, as determined by conditioned place preference (CPP). To encourage bingeing, rats were given 24-h access to water and 12-h-intermittent access to chow plus an intermittent bottle that contained water (control) or 8% solutions of sucrose, glucose or fructose for 9days, followed by ad libitum chow diet and a 10-day cocaine (15mg/kg; i.p.) CPP paradigm. By day 4 of the sugar-bingeing diet, sugar bingeing in the fructose group surpassed the glucose group, with the sucrose group being intermediate. All three sugar groups had similar chow and water intake throughout the diet. In contrast, controls exhibited chow bingeing by day 5 without altering water intake. Similar magnitudes of cocaine CPP were observed in rats with a history of sucrose, fructose or chow (control) bingeing. Notably, the glucose-bingeing rats did not demonstrate a significant cocaine CPP despite showing similar cocaine-induced locomotor activity as the other diet groups. Overall, these results show that fructose and glucose, the monosaccharide components of sucrose, produce divergent degrees of bingeing and cocaine reward.

  19. Pilot Study on the Homeopathic Treatment of Binge Eating in Males.

    Science.gov (United States)

    van Heerden, Hertzog Johannes; Razlog, Radmila; Pellow, Janice

    2016-04-01

    Context • Frequent binge eating is often a symptom of an underlying eating disorder, such as bulimia nervosa (BN) or binge eating disorder (BED). The role of homeopathy in the treatment of binge eating remains poorly explored. Objective • The study intended to measure the efficacy of individualized homeopathic treatment for binge eating in adult males. Design • This case study was a 9-wk pilot using an embedded, mixed-methods design. A 3-wk baseline period was followed by a 6-wk treatment period. Setting • The setting was the Homeopathic Health Clinic at the University of Johannesburg in Johannesburg, South Africa. Participants • Through purposive sampling, the research team recruited 15 Caucasian, male participants, aged 18-45 y, who were exhibiting binge eating. Intervention • Individualized homeopathic remedies were prescribed to each participant. Primary Outcome Measures • Participants were assessed by means of (1) a self-assessment calendar (SAC), recording the frequency and intensity of binging; (2) the Binge Eating Scale (BES), a psychometric evaluation of severity; and (3) case analysis evaluating changes with time. Results • Ten participants completed the study. The study found a statistically significant improvement with regard to the BES (P = .003) and the SAC (P = .006), with a large effect size, indicating that a decrease occurred in the severity and frequency of binging behavior during the study period. Conclusions • This small study showed the potential benefits of individualized homeopathic treatment of binge eating in males, decreasing both the frequency and severity of binging episodes. Follow-up studies are recommended to explore this treatment modality as a complementary therapeutic option in eating disorders characterized by binge eating. PMID:27089525

  20. Young Adults' Food Selection Patterns: Relations with Binge Eating and Restraint

    Science.gov (United States)

    Lydecker, Janet A.; Palmberg, Allison A.; Hill, Katherine Vatalaro; Mazzeo, Suzanne E.

    2015-01-01

    Binge eating is increasingly prevalent in college students (White, Reynolds-Malear, & Cordero, 2011). Binge episodes involve eating an objectively large quantity of food in a discrete amount of time and a perceived lost control over eating (American Psychiatric Association [APA], 2013). Strong negative affect commonly precedes and follows each…

  1. Mindfulness-Based Cognitive Therapy Applied to Binge Eating: A Case Study

    Science.gov (United States)

    Baer, Ruth A.; Fischer, Sarah; Huss, Debra B.

    2005-01-01

    Binge eating is a common problem associated with distress and dysfunction. Mindfulness-based interventions are attracting increasing attention, and the recent empirical literature suggests that they may be effective for a variety of disorders. Current theories about the etiology and maintenance of binge eating suggest that mindfulness training may…

  2. Cost-Effectiveness of Guided Self-Help Treatment for Recurrent Binge Eating

    Science.gov (United States)

    Lynch, Frances L.; Striegel-Moore, Ruth H.; Dickerson, John F.; Perrin, Nancy; DeBar, Lynn; Wilson, G. Terence; Kraemer, Helena C.

    2010-01-01

    Objective: Adoption of effective treatments for recurrent binge-eating disorders depends on the balance of costs and benefits. Using data from a recent randomized controlled trial, we conducted an incremental cost-effectiveness analysis (CEA) of a cognitive-behavioral therapy guided self-help intervention (CBT-GSH) to treat recurrent binge eating…

  3. Binge Eating and Weight-Related Quality of Life in Obese Adolescents

    Directory of Open Access Journals (Sweden)

    Margaret Keil

    2012-03-01

    Full Text Available Limited data exist regarding the association between binge eating and quality of life (QOL in obese adolescent girls and boys. We, therefore, studied binge eating and QOL in 158 obese (BMI ≥ 95th percentile adolescents (14.5 ± 1.4 years, 68.0% female, 59% African-American prior to weight-loss treatment. Youth completed an interview to assess binge eating and a questionnaire measure of QOL. Controlling for body composition, binge eating youth (n = 35, overall, reported poorer QOL in domains of health, mobility, and self-esteem compared to those without binge eating ( ps < 0.05. Also, girls, overall, reported poorer QOL than boys in activities of daily-living, mobility, self-esteem, and social/interpersonal functioning (ps < 0.05. Girls with binge eating reported the greatest impairments in activities of daily living, mobility, self-esteem, social/interpersonal functioning, and work/school QOL (ps < 0.05. Among treatment-seeking obese adolescents, binge eating appears to be a marker of QOL impairment, especially among girls. Prospective and treatment designs are needed to explore the directional relationship between binge eating and QOL and their impact on weight outcomes.

  4. Rapid Response Predicts Treatment Outcomes in Binge Eating Disorder: Implications for Stepped Care

    Science.gov (United States)

    Masheb, Robin M.; Grilo, Carlos M.

    2007-01-01

    The authors examined rapid response in 75 overweight patients with binge eating disorder (BED) who participated in a randomized clinical trial of guided self-help treatments (cognitive-behavioral therapy [CBTgsh] and behavioral weight loss [BWLgsh]). Rapid response, defined as a 65% or greater reduction in binge eating by the 4th treatment week,…

  5. Metacognitions about desire thinking predict the severity of binge eating in a sample of Italian women.

    Science.gov (United States)

    Spada, Marcantonio M; Caselli, Gabriele; Fernie, Bruce A; Nikčević, Ana V; Ruggiero, Giovanni M; Boccaletti, Fabio; Dallari, Giulia; Sassaroli, Sandra

    2016-06-01

    In this study, our principal aim was to investigate whether metacognitions about desire thinking predict the severity of binge eating in women and, if so, whether this relationship is independent of age, self-reported body mass index (BMI), negative affect, irrational food beliefs and craving. One hundred and four women, consisting of 32 consecutive patients with binge eating disorder undergoing initial assessment for cognitive therapy for eating disorders, 39 moderate binge eaters, and 33 non-binge eaters (both from the general population), completed the following measures: Self-reported BMI, Hospital Anxiety and Depression Scale, Irrational Food Beliefs Scale, General Craving Scale, Metacognitions about Desire Thinking Questionnaire, and Binge Eating Scale. A series of Spearman's rho correlation analyses revealed that self-reported BMI, anxiety, depression, irrational food beliefs, craving, and all three factors of the metacognitions about desire thinking questionnaire were significantly associated with the severity of binge eating. A stepwise regression analysis identified self-reported BMI, craving, and negative metacognitions about desire thinking as significant predictors of the severity of binge eating. These results, taken together, highlight the possible role of metacognitions about desire thinking in predicting the severity of binge eating. The clinical implications of these findings are discussed. PMID:26143571

  6. Binge Eating as Related to Negative Self-Awareness, Depression, and Avoidance Coping in Undergraduates.

    Science.gov (United States)

    Schwarze, Nicole J.; Oliver, J. M.; Handal, P. J.

    2003-01-01

    In an investigation of Heatherton and Baumeister's (1991) theory of binge eating, 207 female undergraduate students were grouped as binge eaters (BE) or non-eating-disordered (NED) for analyses. The BE group scored significantly higher than the NED group on avoidance coping and substance use when depression was not controlled; however, after…

  7. Self-consciousness and binge eating in college women : an escape from rumination?

    NARCIS (Netherlands)

    Dalley, Simon; Donofrio, Stacey

    2014-01-01

    Background: Binge-eating is a highly distressing symptom that has been found to co-occur with other symptoms of eating disorders such as bulimia nervosa. One perspective of binge eating is that it is an attempt to escape high levels of aversive self-consciousness. A primary aim of this study is to e

  8. Beyond inhibition: A dual-process perspective to renew the exploration of binge drinking.

    Directory of Open Access Journals (Sweden)

    Severine eLannoy

    2014-06-01

    Full Text Available Binge drinking is a widespread alcohol-consumption pattern in youth and is linked to cognitive consequences, mostly for executive functions. However, other crucial factors remain less explored in binge drinking and notably the emotional-automatic processes. Dual-process model postulates that addictive disorders are not only due to impaired reflective system (involved in deliberate behaviours, but rather to an imbalance between under-activated reflective system and over-activated affective-automatic one (involved in impulsive behaviours. This proposal has been confirmed in alcohol-dependence, but has not been tested in binge drinking. The observation of comparable impairments in binge-drinking and alcohol-dependence led to the continuum hypothesis, suggesting similar deficits across different alcohol-related disorders. In this perspective, applying the dual-process model to binge drinking might renew the understanding of this continuum hypothesis. A three-axes research agenda will be proposed, exploring: (1 the affective-automatic system in binge drinking; (2 the systems’ interactions and imbalance in binge drinking; (3 the evolution of this imbalance in the transition between binge drinking and alcohol-dependence.

  9. Associated Factors for Self-Reported Binge Eating among Male and Female Adolescents.

    Science.gov (United States)

    Ledoux, Sylvie; And Others

    1993-01-01

    Adolescents (n=3,287) completed questionnaire concerning eating behaviors. Found that binge eaters had disorderly eating habits (skipping meals, snacking, eating sweets, unbalanced diets), concern with body shape (feeling too fat), and depressive symptoms more often than nonbinge eaters did. Relationship between binging episodes and eating habits,…

  10. A Controlled Evaluation of the Distress Criterion for Binge Eating Disorder

    Science.gov (United States)

    Grilo, Carlos M.; White, Marney A.

    2011-01-01

    Objective: Research has examined various aspects of the validity of the research criteria for binge eating disorder (BED) but has yet to evaluate the utility of Criterion C, "marked distress about binge eating." This study examined the significance of the marked distress criterion for BED using 2 complementary comparison groups. Method: A total of…

  11. A Controlled Evaluation of the Distress Criterion for Binge Eating Disordspan>er

    Science.gov (United States)

    Grilo, Carlos M.; White, Marney A.

    2011-01-01

    Objective: Research has examined various aspects of the validity of the research criteria for binge eating disorder (BED) but has yet to evaluate the utility of Criterion C, "marked distress about binge eating." This study examined the significance of the marked distress criterion for BED using 2 complementary comparison groups. Method: A total of…

  12. Impact of maternal negative affectivity on light alcohol use and binge drinking during pregnancy

    DEFF Research Database (Denmark)

    Stene-Larsen, Kim; Torgersen, Leila; Strandberg-Larsen, Katrine;

    2013-01-01

    To investigate whether maternal negative affectivity, a tendency to frequent negative emotions and views, is associated with light alcohol use and binge drinking during pregnancy.......To investigate whether maternal negative affectivity, a tendency to frequent negative emotions and views, is associated with light alcohol use and binge drinking during pregnancy....

  13. Time Perspective and Psychosocial Positive Functioning among Italian Adolescents Who Binge Eat and Drink

    Science.gov (United States)

    Laghi, Fiorenzo; Liga, Francesca; Baumgartner, Emma; Baiocco, Roberto

    2012-01-01

    Evidence of an association between binge eating and binge drinking and of related health consequences have stimulated investigators to examine and explore risk and protective factors plus the reasons why individuals engage in these risky behaviours (Benjamin & Wulfert, 2003; Ferriter & Ray, 2011). This study examined the relationship between binge…

  14. The Utility of a Gender-Specific Definition of Binge Drinking on the AUDIT

    Science.gov (United States)

    Olthuis, Janine V.; Zamboanga, Byron L.; Ham, Lindsay S.; Van Tyne, Kathryne

    2011-01-01

    Objective: Although binge drinking is commonly defined as the consumption of at least 5 drinks in 1 sitting for men and 4 for women, the Alcohol Use Disorders Identification Test (AUDIT) defines binge drinking as the consumption of 6 or more drinks in 1 sitting for both men and women. This study examined the effect of using gender-specific binge…

  15. Binge Drinking and Rape: A Prospective Examination of College Women with a History of Previous Sexual Victimization

    Science.gov (United States)

    McCauley, Jenna L.; Calhoun, Karen S.; Gidycz, Christine A.

    2010-01-01

    The current study prospectively examined the longitudinal relationships between binge drinking behavior and rape experiences among a multisite sample of college women with a history of prior attempted or completed rape (N = 228). Rates of binge drinking among this high-risk sample were high. Prospective analyses indicated that binge drinking…

  16. Perceptions and practices of student binge drinking: an observational study of residential college students.

    Science.gov (United States)

    Clinkinbeard, Samantha S; Johnson, Michael A

    2013-01-01

    Professionals have debated the use of the term binge drinking over the past couple of decades, yet little attention has been paid to college student perceptions. We explored how students at one university qualitatively defined binge drinking; whether their own definitions coincided with those adopted by researchers; and whether students' own definitions varied according to their behavior. The most common definition provided by students included a description of the consumption of a large, non-specific, amount of alcohol. Only half of the students who, by standard definition, participated in binge drinking in the previous 30 days actually identified their behavior as such. Finally, binge drinkers were more likely to define binge drinking in an extreme manner such that it results in vomiting or blacking out.

  17. The effect of alcohol binge drinking in early pregnancy on general intelligence in children

    DEFF Research Database (Denmark)

    Kesmodel, Ulrik S.; Eriksen, H-L Falgreen; Underbjerg, Mette;

    2012-01-01

    , home environment, postnatal parental smoking, health status, and indicators for hearing and vision impairment. Main outcome measure  WPPSI-R. Results  There were no systematic or significant differences in general intelligence between children of mothers reporting binge drinking and children of mothers......Please cite this paper as: Kesmodel U, Falgreen Eriksen H, Underbjerg M, Kilburn T, Støvring H, Wimberley T, Mortensen E. The effect of alcohol binge drinking in early pregnancy on general intelligence in children. BJOG 2012;119:1222-1231. Objective  To examine the effects of binge alcohol...... consumption during early pregnancy, including the number of binge episodes and the timing of binge drinking, on general intelligence in 5-year-old children. Design  Follow-up study. Setting  Neuropsychological testing in four Danish cities 2003-2008. Population  A cohort of 1617 women and their children...

  18. Characteristics of women who binge drink before and after they become aware of their pregnancy

    DEFF Research Database (Denmark)

    Strandberg-Larsen, Katrine; Rod Nielsen, Naja; Nybo Andersen, Anne-Marie;

    2008-01-01

    Background Consumption of high doses of alcohol on a single occasion (binge drinking) may harm the developing foetus and pregnant women are advised to avoid binge drinking while pregnant. We present characteristics of Danish women who binge drank in the pre-and post recognised part of their...... pregnancy. Methods During the years 1996-2002 approximately 100,000 pregnant women were enrolled into the Danish National Birth Cohort. Women with information on binge drinking, time of recognition of pregnancy, age, reproductive history, marital status, smoking, occupational status, pre-pregnancy BMI......, alcohol consumption before pregnancy, and mental disorders (n = 85,334) were included in the analyses. Results Approximately one quarter of the women reported binge drinking at least once during pregnancy; most of these in the pre-recognised part of pregnancy. Weekly alcohol consumption before pregnancy...

  19. Characteristics of binge eating disorder in relation to diagnostic criteria

    Science.gov (United States)

    Wilfley, Denise E; Citrome, Leslie; Herman, Barry K

    2016-01-01

    The objective of this review was to examine the evidentiary basis for binge eating disorder (BED) with reference to the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (DSM-5) diagnostic criteria for BED. A PubMed search restricted to titles and abstracts of English-language reviews, meta-analyses, clinical trials, randomized controlled trials, journal articles, and letters using human participants was conducted on August 7, 2015, using keywords that included “binge eating disorder,” DSM-5, DSM-IV, guilt, shame, embarrassment, quantity, psychological, behavior, and “shape and weight concerns.” Of the 257 retrieved publications, 60 publications were considered relevant to discussions related to DSM-5 diagnostic criteria and were included in the current review, and 20 additional references were also included on the basis of the authors’ knowledge and/or on a review of the reference lists from relevant articles obtained through the literature search. Evidence supports the duration/frequency criterion for BED and the primary importance of loss of control and marked distress in identifying individuals with BED. Although overvaluation of shape/weight is not a diagnostic criterion, its relationship to the severity of BED psychopathology may identify a unique subset of individuals with BED. Additionally, individuals with BED often exhibit a clinical profile consisting of psychiatric (eg, mood, obsessive–compulsive, and impulsive disorders) and medical (eg, gastrointestinal symptoms, metabolic syndrome, and type 2 diabetes) comorbidities and behavioral profiles (eg, overconsumption of calories outside of a binge eating episode and emotional eating). Future revisions of the BED diagnostic criteria should consider the inclusion of BED subtypes, perhaps based on the overvaluation of shape/weight, and an evidence-based reassessment of severity criteria.

  20. Alexithymia, depression, anxiety and binge eating in obese women

    Directory of Open Access Journals (Sweden)

    Agnieszka Źak-Gołąb

    2013-09-01

    Full Text Available Background and Objectives: Alexithymia is a personality trait that may affect the development and course of obesity and effectiveness of treatment. The aim of the study is to assess the prevalence of alexithymia in obese women beginning a weight reduction program and determine the relationships between alexithymia and anxiety, depression, and binge eating. Methods: Obese women (n = 100; age 45 ± 13 yr completed the following self-report inventories: Toronto Alexithymia Scale (TAS 26, Hospital Anxiety and Depression Scale (HADS, and Binge Eating Scale (BES. Results: Alexithymia was found in 46 patients and was more frequent among women who had attained only primary and vocational education than in those with a higher education level (39.1% vs. 10.9%; p = 0.002 and in those >45 years old than in younger women (30.4% vs. 69.6%; p = 0.03. The frequency of severe depression symptoms was higher in alexithymic women than in non-alexithymic women (19.6% vs. 5.6%; p = 0.03; however, the anxiety state was equally prevalent in both subgroups. The prevalence of alexithymia (52.6% vs. 44.4% and its level (73.2 ± 8.9 vs. 71.2 ± 11.3 points were similar in women with and without binge eating disorder. Multivariate mixed linear regression analysis revealed that higher body mass index was associated with primary and vocational education (odds ratio [OR] = 16.69 and severe depression symptoms (OR = 52.45, but not alexithymia. Conclusions: In addition to severe depression and low education level, obesity may predispose for the development of alexithymia. However, alexithymia does not affect the severity of obesity in women.

  1. Characteristics of binge eating disorder in relation to diagnostic criteria.

    Science.gov (United States)

    Wilfley, Denise E; Citrome, Leslie; Herman, Barry K

    2016-01-01

    The objective of this review was to examine the evidentiary basis for binge eating disorder (BED) with reference to the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) diagnostic criteria for BED. A PubMed search restricted to titles and abstracts of English-language reviews, meta-analyses, clinical trials, randomized controlled trials, journal articles, and letters using human participants was conducted on August 7, 2015, using keywords that included "binge eating disorder," DSM-5, DSM-IV, guilt, shame, embarrassment, quantity, psychological, behavior, and "shape and weight concerns." Of the 257 retrieved publications, 60 publications were considered relevant to discussions related to DSM-5 diagnostic criteria and were included in the current review, and 20 additional references were also included on the basis of the authors' knowledge and/or on a review of the reference lists from relevant articles obtained through the literature search. Evidence supports the duration/frequency criterion for BED and the primary importance of loss of control and marked distress in identifying individuals with BED. Although overvaluation of shape/weight is not a diagnostic criterion, its relationship to the severity of BED psychopathology may identify a unique subset of individuals with BED. Additionally, individuals with BED often exhibit a clinical profile consisting of psychiatric (eg, mood, obsessive-compulsive, and impulsive disorders) and medical (eg, gastrointestinal symptoms, metabolic syndrome, and type 2 diabetes) comorbidities and behavioral profiles (eg, overconsumption of calories outside of a binge eating episode and emotional eating). Future revisions of the BED diagnostic criteria should consider the inclusion of BED subtypes, perhaps based on the overvaluation of shape/weight, and an evidence-based reassessment of severity criteria. PMID:27621631

  2. Accreditation and the Credit Hour.

    Science.gov (United States)

    Wellman, James V.

    2003-01-01

    Reviews the role that accreditation plays in defining and enforcing the credit-hour measure. Regional accreditation agencies are generally more flexible in terms of defining credit hours than are national agencies, which are more rigid in their expectations. Specialized accrediting agencies usually make the least mention of credit units. (SLD)

  3. Binge drinking among Arab/Chaldeans: an exploratory study.

    Science.gov (United States)

    Arfken, Cynthia L; Owens, Darlene; Said, Manal

    2012-01-01

    Focus groups were conducted with young Arab/Chaldeans (N = 82) from different ethno-religious groups (Chaldeans, Orthodox Christians, and Muslims) to explore the potential risk and the protective factors associated with the high level of binge (or episodic heavy) drinking among Arab/Chaldeans reported by general population surveys. Most of the participants were aware of and knowledgeable about the problem in their community. Themes identified as contributory factors consistent across ethno-religious groups included the availability of alcohol, the importance of family, conformity to group behavior, and social reasons. Differences included the context for drinking and gender roles. These findings can be used to tailor culturally appropriate interventions.

  4. Using Classifiers to Identify Binge Drinkers Based on Drinking Motives.

    Science.gov (United States)

    Crutzen, Rik; Giabbanelli, Philippe

    2013-08-21

    A representative sample of 2,844 Dutch adult drinkers completed a questionnaire on drinking motives and drinking behavior in January 2011. Results were classified using regressions, decision trees, and support vector machines (SVMs). Using SVMs, the mean absolute error was minimal, whereas performance on identifying binge drinkers was high. Moreover, when comparing the structure of classifiers, there were differences in which drinking motives contribute to the performance of classifiers. Thus, classifiers are worthwhile to be used in research regarding (addictive) behaviors, because they contribute to explaining behavior and they can give different insights from more traditional data analytical approaches. PMID:23964957

  5. Characteristics of binge eating disorder in relation to diagnostic criteria

    Directory of Open Access Journals (Sweden)

    Wilfley DE

    2016-08-01

    Full Text Available Denise E Wilfley,1 Leslie Citrome,2 Barry K Herman3 1Department of Psychiatry, Washington University School of Medicine, St Louis, MO, 2Department of Psychiatry & Behavioral Sciences, New York Medical College, Valhalla, NY, 3Global Medical Affairs, Shire, Lexington, MA, USA Abstract: The objective of this review was to examine the evidentiary basis for binge eating disorder (BED with reference to the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (DSM-5 diagnostic criteria for BED. A PubMed search restricted to titles and abstracts of English-language reviews, meta-analyses, clinical trials, randomized controlled trials, journal articles, and letters using human participants was conducted on August 7, 2015, using keywords that included “binge eating disorder,” DSM-5, DSM-IV, guilt, shame, embarrassment, quantity, psychological, behavior, and “shape and weight concerns.” Of the 257 retrieved publications, 60 publications were considered relevant to discussions related to DSM-5 diagnostic criteria and were included in the current review, and 20 additional references were also included on the basis of the authors’ knowledge and/or on a review of the reference lists from relevant articles obtained through the literature search. Evidence supports the duration/frequency criterion for BED and the primary importance of loss of control and marked distress in identifying individuals with BED. Although overvaluation of shape/weight is not a diagnostic criterion, its relationship to the severity of BED psychopathology may identify a unique subset of individuals with BED. Additionally, individuals with BED often exhibit a clinical profile consisting of psychiatric (eg, mood, obsessive–compulsive, and impulsive disorders and medical (eg, gastrointestinal symptoms, metabolic syndrome, and type 2 diabetes comorbidities and behavioral profiles (eg, overconsumption of calories outside of a binge eating episode and emotional

  6. Do executive functioning deficits underpin binge eating disorder? A comparison of overweight women with and without binge eating pathology

    Science.gov (United States)

    Manasse, Stephanie M.; Forman, Evan M.; Ruocco, Anthony C.; Butryn, Meghan L.; Juarascio, Adrienne S.; Fitzpatrick, Kathleen Kara

    2015-01-01

    Objective Deficits in executive function (EF) --including inhibitory control, cognitive flexibility, decision-making, and working memory--may be risk or maintenance factors for binge eating disorder (BED). However, there is mixed evidence regarding EF deficits in individuals with BED. Significant methodological weaknesses (e.g., use of a single EF measure, omission of relevant covariates) in the current literature represent one reason for lack of consensus. Methods The current study compared EF in a sample of overweight women with (n=31) and without (n=43) full or sub-threshold BED, with the aim of conducting a multi-faceted investigation of the neurocognitive profile of BED. A neuropsychological battery of EF was administered to all participants. Results After controlling for IQ and age, individuals with binge eating displayed significantly poorer performance on tasks of problem-solving and inhibitory control, and displayed higher prioritization of immediate versus delayed rewards, but the two groups did not appear to differ on set-shifting, working memory, and risk taking. Differences in inhibitory control were no longer statistically significant when depressive symptomology was added as a covariate and correction for multiple comparisons was applied. Exploratory analyses indicated that full and sub-threshold BED groups did not differ in EF. Discussion Results partially support the hypothesis of relative EF deficits in individuals with BED, suggesting that binge eating may be maintained by cognitive factors distinct from those of obesity. Future research should aim to replicate with a larger sample, control for a wider range of psychiatric comorbidities, and examine whether EF deficits predict treatment outcome. PMID:25644028

  7. Cravings and food consumption in Binge Eating Disorder.

    Science.gov (United States)

    Ng, Longena; Davis, Caroline

    2013-12-01

    The purpose of this study was to extend existing work that examines the role of cravings in Binge Eating Disorder (BED). The current study uses a case-control design to establish a relationship between cravings and food exposure, and between cravings and food consumption in individuals diagnosed with BED. Twenty-nine females with BED, 40 obese controls, and 50 normal-weight controls were first presented with a neutral cue and completed a food-craving measure. They were then presented with their favourite snack food and completed the craving measure again, after which they were allowed to consume the food. The BED group had significantly higher scores for pre- and post-craving measures, and consumed more food compared to the controls. There was, however, no significant interaction between group and craving scores. Results also showed a positive correlation between food consumption and cravings scores both before and after food exposure for individuals with BED. The findings suggest that the level of cravings prior to food exposure may be sufficient to predict overeating in BED and that treatment may want to target this as a defining feature that differentiates individuals with BED from those who do not binge eat.

  8. The theory of planned behavior and binge drinking among undergraduate students: assessing the impact of habit strength.

    Science.gov (United States)

    Norman, Paul

    2011-05-01

    The present study sought to apply the theory of planned behavior (TPB) to the prediction of binge drinking intentions and behavior among undergraduate students and to test whether habit strength explains additional variance in binge drinking behavior. Undergraduate students (N=137) completed measures of the TPB (i.e., attitude, subjective norm, self-efficacy, perceived control, and intention) and habit strength (Self-Report Habit Index) in relation to binge drinking. Frequency of binge drinking was assessed one month later (n=109). The TPB explained 75% of the variance in binge drinking intentions, with attitude and self-efficacy making significant contributions, and 35% of the variance in binge drinking behavior at one-month follow-up, with only intention making a significant contribution. Habit strength explained additional variance in binge drinking behavior (∆R(2)=.06), although intention remained as a significant predictor. The results suggest that binge drinking among undergraduate students is under the control of both intentional and habitual processes. Interventions to reduce binge drinking should therefore focus on the motivational determinants (e.g., perceived positive and negative consequences) of binge drinking as well as the environmental factors (i.e., contextual cues) that promote binge drinking. PMID:21310540

  9. Prevalence and Correlates of Binge Drinking among Young Adults Using Alcohol: A Cross-Sectional Survey

    Directory of Open Access Journals (Sweden)

    Francesco Bartoli

    2014-01-01

    Full Text Available Background. Although binge drinking prevalence and correlates among young people have been extensively studied in the USA and Northern Europe, less is known for Southern Europe countries with relatively healthier drinking cultures. Objective. We aimed at analyzing prevalence and correlates of binge drinking in a representative sample of young adults in Italy. Methods. We conducted a cross-sectional survey among alcohol-consuming young adults. We carried out univariate and multivariate analyses to assess associations between recent binge drinking and candidate variables. Results. We selected 654 subjects, with 590 (mean age: 20.65 ± 1.90 meeting inclusion criteria. Prevalence for recent binge drinking was 38.0%, significantly higher for females than males. Multivariate analysis showed that high alcohol expectancies, large amount of money available during the weekend, interest for parties and discos, female gender, cannabis use, influence by peers, and electronic cigarettes smoking all were significantly associated with recent binge drinking, whereas living with parents appeared a significant protective factor. Conclusions. More than a third of young adults using alcohol are binge drinkers, and, in contrast with findings from Anglo-Saxon countries, females show higher risk as compared with males. These data suggest the increasing importance of primary and secondary prevention programmes for binge drinking.

  10. Bulimics' responses to food cravings: is binge-eating a product of hunger or emotional state?

    Science.gov (United States)

    Waters, A; Hill, A; Waller, G

    2001-08-01

    This study examined the roles of hunger, food craving and mood in the binge-eating episodes of bulimic patients, and identified the critical factors involved in the processes surrounding binge-eating episodes that follow cravings. This was a prospective study of the binge-eating behaviour of 15 women with bulimia nervosa. The participants used food intake diaries and Craving Records to self-monitor their nutritional behaviour, hunger levels and affective state. Cravings leading to a binge were associated with higher tension, lower mood and lower hunger than those cravings not leading to a binge. Levels of tension and hunger were the critical discriminating variables. The findings of the study support empirical evidence and models of emotional blocking in binge-eating behaviour and challenge the current cognitive starve-binge models of bulimia. The role of food cravings in the emotional blocking model is discussed in terms of a classically conditioned motivational state. Implications for treatment are addressed. PMID:11480829

  11. BINGE EATING DISORDER AND QUALITY OF LIFE OF CANDIDATES TO BARIATRIC SURGERY

    Science.gov (United States)

    COSTA, Ana Júlia Rosa Barcelos; PINTO, Sônia Lopes

    2015-01-01

    Background : Obesity decreases the quality of life, which is aggravated by the association of comorbidities, and the binge eating disorder is directly related to body image and predisposes to overweight. Aim: Evaluate association between the presence and the level of binge eating disorder and the quality of life of the obese candidates for bariatric surgery. Methods : Cross-sectional study analyzing anthropometric data (weight and height) and socioeconomics (age, sex, marital status, education and income). The application of Binge Eating Scale was held for diagnosis of Binge Eating Disorder and the Medical Outcomes Study 36-item Short-From Health Survey to assess the quality of life. Results : Total sample studied was 96 patients, mean age 38.15±9.6 years, 80.2% female, 67.7% married, 41% with complete and incomplete higher education, 77.1% with lower income or equal to four the minimum salary, 59.3% with grade III obesity. Binge eating disorder was observed in 44.2% of patients (29.9% moderate and 14.3% severe), and these had the worst scores in all domains of quality of life SF36 scale; however, this difference was not statistically significant. Only the nutritional status presented significant statistically association with the presence of binge eating disorder. Conclusion : High prevalence of patients with binge eating disorder was found and they presented the worst scores in all domains of quality of life. PMID:26537275

  12. Baclofen reduces binge eating in a double-blind, placebo-controlled, crossover study.

    Science.gov (United States)

    Corwin, Rebecca L; Boan, Jarol; Peters, Kathryn F; Ulbrecht, Jan S

    2012-09-01

    Baclofen has shown promise in treating substance use disorders and also reduced binge frequency in an open-label trial. This placebo-controlled, double-blind, crossover study further assessed the effects of baclofen on binge eating. Twelve individuals who self-reported binge eating completed the study. Data were collected during a run-in period (no drug or placebo), placebo phase (48 days), and baclofen phase (titrated up to 60 mg daily or the maximum tolerated dose, 48 days). All the participants were exposed to all conditions. Participants completed a binge diary daily, and the Binge Eating Scale (BES), Food Craving Inventory-II (FCI-II), and Hospital Anxiety and Depression Scale (HADS) at regular intervals throughout the study. Baclofen significantly reduced binge frequency relative to placebo and run-in (Peffects. Tiredness, fatigue, and upset stomach were the most commonly reported side-effects. These results indicate that baclofen may be a useful treatment for binge eating in some patients. PMID:22854310

  13. The 72-Hour WEBT Microvariability Observation of Blazar S5 0716+714 in 2009

    CERN Document Server

    Bhatta, G; Hollingsworth, H; Dhalla, S; Khanuja, A; Bachev, R; Blinov, D A; Bottcher, M; Calle, O J A Bravo; Calcidese, P; Capezzali, D; Carosati, D; Chigladze, R; Collins, A; Coloma, J M; Efimov, Y; Gupta, A C; Hu, S-M; Kurtanidze, O; Lamerato, A; Larionov, V M; Lee, C -U; Lindfors, E; Murphy, B; Nilsson, K; Ohlert, J M; Oksanen, A; Paakkonen, P; Pollock, J T; Rani, B; Reinthal, R; Rodriguez, D; Ros, J A; Roustazadeh, P; Sagar, R; Sanchez, A; Shastri, P; Sillanpaa, A; Strigachev, A; Takalo, L; Vennes, S; Villata, M; Villforth, C; Wu, J; Zhou, X

    2013-01-01

    Context. The international whole earth blazar telescope (WEBT) consortium planned and carried out three days of intensive micro-variability observations of S5 0716+714 from February 22, 2009 to February 25, 2009. This object was chosen due to its bright apparent magnitude range, its high declination, and its very large duty cycle for micro-variations. Aims. We report here on the long continuous optical micro-variability light curve of 0716+714 obtained during the multi-site observing campaign during which the Blazar showed almost constant variability over a 0.5 magnitude range. The resulting light curve is presented here for the first time. Observations from participating observatories were corrected for instrumental diff?erences and combined to construct the overall smoothed light curve. Methods. Thirty-six observatories in sixteen countries participated in this continuous monitoring program and twenty of them submitted data for compilation into a continuous light curve. The light curve was analyzed using se...

  14. 72-Hour Forecast of Air Temperatures from the National Weather Service's National Digital Forecast Database (NDFD)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Digital Forecast Database (NDFD) contains a seamless mosaic of the National Weather Service's (NWS) digital forecasts of air temperature. In...

  15. 72-Hour Forecast of Precipitation Amounts from the National Weather Service's National Digital Forecast Database (NDFD)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Digital Forecast Database (NDFD) contains a seamless mosaic of the National Weather Service's (NWS) digital forecasts of precipitation amounts. In...

  16. "Regaining control by losing control" : a qualitative study into the experience of binge eating disorder

    OpenAIRE

    2007-01-01

    This study seeks to provide an insider’s perspective on the experience of Binge Eating Disorder as it is brought to light from interviews with eight women. Binge Eating Disorder is a recently described and proposed new category of eating disorders characterized by “recurrent episodes of binge eating in the absence of the regular use of inappropriate compensatory behaviours characteristic of Bulimia Nervosa, and a sense of loss of control over eating during the episode.” Based on a phenomenolo...

  17. Excel VBA 24-hour trainer

    CERN Document Server

    Urtis, Tom

    2015-01-01

    Master VBA automation quickly and easily to get more out of Excel Excel VBA 24-Hour Trainer, 2nd Edition is the quick-start guide to getting more out of Excel, using Visual Basic for Applications. This unique book/video package has been updated with fifteen new advanced video lessons, providing a total of eleven hours of video training and 45 total lessons to teach you the basics and beyond. This self-paced tutorial explains Excel VBA from the ground up, demonstrating with each advancing lesson how you can increase your productivity. Clear, concise, step-by-step instructions are combined wit

  18. Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs.

    Science.gov (United States)

    Wen, S F; Parthasarathy, R; Iliopoulos, O; Oberley, T D

    1992-09-01

    Two college students who developed reversible acute deterioration in renal function following binge drinking of beer and the use of nonsteroidal antiinflammatory drugs (NSAIDs) are reported. Both patients presented with back and flank pain with muscle tenderness, but showed no evidence of overt rhabdomyolysis. The first case had marked renal failure, with a peak serum creatinine reaching 575 mumol/L (6.5 mg/dL), and acute tubular necrosis was documented by renal biopsy. The second case had only modest elevation in serum creatinine, and renal function rapidly improved on rehydration. The contribution of the potential muscle damage associated with alcohol ingestion to the changes in renal function in these two cases is not clear. However, the major mechanism for the acute renal failure was thought to be related to inhibition of renal prostaglandin synthesis in the face of compromised renal hemodynamics secondary to alcohol-induced volume depletion. PMID:1519610

  19. Patterns of binge drinking at an international nightlife resort

    DEFF Research Database (Denmark)

    Tutenges, Sébastien; Hesse, Morten

    2008-01-01

    AIMS: The aim of this study was to compare the patterns of substance use in young Danes while holidaying in the Bulgarian holiday resort of Sunny Beach (SB) to their patterns of substance use in Denmark. METHODS: Data were collected from visitors to SB in 2007 (n = 1011). Information on alcohol...... nightlife resorts provide a context for excess in drug use and alcohol use. Alcohol poses a potentially severe threat to the short- and long-term health of young tourists, but little attention has been paid to form interventions targeting binge drinking in nightlife resorts....... and drug use was surveyed using a short questionnaire. Findings: Most individuals surveyed were regular drinkers in Denmark, and the use of most illicit drugs was rare. Patterns of substance use in SB revealed heavy drinking was common, both in adolescents and young adults. CONCLUSIONS: International...

  20. A primer on binge eating disorder diagnosis and management.

    Science.gov (United States)

    Citrome, Leslie

    2015-12-01

    Binge eating disorder (BED) is the most common eating disorder, with an estimated lifetime prevalence of 2.6% among U.S. adults, yet often goes unrecognized. In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), BED is defined by recurrent episodes of binge eating (eating in a discrete period of time an amount of food larger than most people would eat in a similar amount of time under similar circumstances and a sense of lack of control over eating during the episode), occurring on average at least once a week for 3 months, and associated with marked distress. It can affect both men and women, regardless if they are at normal weight, overweight, or obese, and regardless of their ethnic or racial group. Psychiatric comorbidities are very common, with 79% of adults with BED also experiencing anxiety disorders, mood disorders, impulse control disorders, or substance use disorders; almost 50% of persons with BED have ≥ 3 psychiatric comorbidities. Multiple neurobiological explanations have been proffered for BED, including dysregulation in reward center and impulse control circuitry, with potentially related disturbances in dopamine neurotransmission and endogenous μ-opioid signaling. Additionally, there is interplay between genetic influences and environmental stressors. Psychological treatments such as cognitive behavioral interventions have been recommended as first line and are supported by meta-analytic reviews. Unfortunately, routine medication treatments for anxiety and depression do not necessarily ameliorate the symptoms of BED; however, at present, there is one approved agent for the treatment of moderate to severe BED-lisdexamfetamine, a stimulant that was originally approved for the treatment of attention deficit hyperactivity disorder.

  1. Diagnosing binge eating disorder in a primary care setting.

    Science.gov (United States)

    Montano, C Brendan; Rasgon, Natalie L; Herman, Barry K

    2016-01-01

    Binge eating disorder (BED), now recognized as a distinct eating disorder in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, is the most prevalent eating disorder. Although nearly half of individuals with BED are obese, BED also occurs in nonobese individuals. Despite the relatively high percentage of weight loss treatment-seeking individuals meeting BED criteria, primary care physicians may not be familiar with or have ever diagnosed BED. Many providers may also have difficulty distinguishing BED as a contributory factor in obesity. This review differentiates BED from other causes of obesity by describing how obese individuals with BED differ from obese individuals without BED and from nonobese individuals with BED in areas including psychopathology, behavior, genetics, physiology, quality of life and productivity. The ways in which health-care providers can identify individuals who may have BED are also highlighted so the proper course of treatment is pursued. Overall, obese individuals with BED demonstrate a number of key characteristics that differentiate them from obese individuals without eating disorders, including increased impulsivity in response to food stimuli with loss of control over eating, resulting in the consumption of more calories. They also experience significant guilt and other negative emotions following a meal. In addition, individuals with BED patients have more psychiatric comorbidity, display more psychopathology, exhibit longer binge durations, consume more meals as snacks during the day and have less dietary restraint compared with individuals with BED who are not obese. However, the differences between individuals with BED who are obese versus not obese are not as prominent. Taken together, the evidence appears to support the conclusion that BED is a unique and treatable neurobehavioral disorder associated with distinct behavioral and psychological profiles and distinct medical and functional outcomes, and that

  2. Predicting Binge Drinking in College Students: Rational Beliefs, Stress, or Loneliness?

    Science.gov (United States)

    Chen, Yixin; Feeley, Thomas Hugh

    2015-01-01

    We proposed a conceptual model to predict binge-drinking behavior among college students, based on the theory of planned behavior and the stress-coping hypothesis. A two-wave online survey was conducted with predictors and drinking behavior measured separately over 2 weeks' time. In the Wave 1 survey, 279 students at a public university in the United States answered questions assessing key predictors and individual characteristics. In the Wave 2 survey, 179 participants returned and reported their drinking behavior over 2 weeks' time. After conducting a negative binomial regression, we found that more favorable attitude toward drinking and less perceived control of drinking at Wave 1 were associated with more binge drinking at Wave 2; subjective norm at Wave 1 was not a significant predictor of binge drinking at Wave 2; students with higher stress at Wave 1 engaged in more binge drinking at Wave 2, but those with higher loneliness did not. Implications of findings are discussed.

  3. Emotional eating moderates the relationship of night eating with binge eating and body mass.

    Science.gov (United States)

    Meule, Adrian; Allison, Kelly C; Platte, Petra

    2014-03-01

    Night eating syndrome is marked by substantial evening or nocturnal food intake, insomnia, morning anorexia, and depressed mood. Night eating severity has been positively associated with body mass index (BMI), binge eating frequency, and emotional eating tendencies. We conducted an online questionnaire study among students (N=729) and explored possible interactive effects between those variables. Night eating severity, binge eating frequency, BMI and emotional eating were all positively correlated with each other. Regression analyses showed that night eating severity was particularly related to more frequent binge episodes and higher BMI at high levels of emotional eating but unrelated to those variables at low levels of emotional eating. Thus, eating as a means of emotion regulation appears to be an important moderator of the relationship between night eating and both binge eating and BMI. PMID:24293184

  4. News of CanalUGR tracked on Google News, Yahoo! News and Bing News

    OpenAIRE

    Herrero-Solana, V??ctor; Arboledas M??rquez, Luis; Leger??n-??lvarez, Elisa

    2013-01-01

    Dataset contains 613 news of CanalUGR (University of Granada Communication Office) tracked on the main online news aggregators (Google News, Yahoo! News and Bing News). We include: number in CanalUGR, media, country, type.

  5. Evaluation of a functional treatment for binge eating associated with bulimia nervosa.

    Science.gov (United States)

    Giddings, T D; Miltenberger, R G

    2010-01-01

    Binge-eating disorders (BED) are a common problem affecting up to 5 percent of the American population in any given 6-month period. Currently, the most widely accepted treatment is some variation of Cognitive Behavior Therapy, although the abstinence rates following this type of treatment are only around 50%. A recent study by Bosch et al. explored the effects of extinction with four women who engaged in binge-eating behavior associated with BED and bulimia nervosa (BN). The treatment was successful, with three of the four participants obtaining abstinence. To date, this has been the only study examining this procedure. The purpose of the current study was to further evaluate extinction of binge eating with four young women who met diagnostic criteria for BN. The results showed that the treatment decreased binge eating to zero for all four women, although one dropped out of the study shortly after beginning the intervention.

  6. The Impact of Price, Availability, and Alcohol Control Policies on Binge Drinking in College

    OpenAIRE

    Frank J. Chaloupka; Henry Wechsler

    1995-01-01

    The effects of beer prices, alcohol availability, and policies related to driving under the influence of alcohol on drinking and binge drinking among youths and young adults are estimated using data from a nationally representative survey of students in U.S. colleges and universities. Drinking participation, participation in binge drinking and level of drinking equations are estimated using appropriate econometric methods. The estimates indicate that the drinking practices of college students...

  7. Binge Drinking – Nationwide Problem, Local Solutions PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2012-01-03

    This 60 second PSA is based on the January 2012 CDC Vital Signs report. One in six adults binge drinks about four times a month. It's a problem nationwide but community-based strategies, such as reducing access to alcohol and increasing the price, can prevent binge drinking.  Created: 1/3/2012 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/3/2012.

  8. Vital Signs – Binge Drinking Among Women and Girls

    Centers for Disease Control (CDC) Podcasts

    2013-01-08

    This podcast is based on the January 2013 CDC Vital Signs report, which presents information about binge drinking among women and girls. Binge drinking is defined for women as four or more drinks in a short period of time. It puts women and girls at greater risk for breast cancer, sexual assault, heart disease, and unintended pregnancy.  Created: 1/8/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/8/2013.

  9. Evaluation of the DSM-5 Severity Indicator for Binge Eating Disorder in a Community Sample

    OpenAIRE

    Grilo, Carlos M.; Ivezaj, Valentina; White, Marney A.

    2015-01-01

    Research has examined various aspects of the diagnostic criteria for binge-eating disorder (BED) but has yet to evaluate the DSM-5 severity criterion. This study examined the DSM-5 severity criterion for BED based on binge-eating frequency and tested an alternative severity specifier based on overvaluation of shape/weight. 338 community volunteers categorized with DSM-5 BED completed a battery of self-report instruments. Participants were categorized first using DSM-5 severity levels and seco...

  10. Binge Drinking Trajectories from Adolescence to Young Adulthood: The Effects of Peer Social Network

    OpenAIRE

    Hahm, Hyeouk Chris; Kolaczyk, Eric; Jang, Jisun; Swenson, Theadora; Bhindarwala, Asma Moiz

    2012-01-01

    This study investigates an association between social network characteristics and binge drinking from adolescence to young adulthood, utilizing National Longitudinal Study of Adolescent Health (n = 7,966) and employing social network and longitudinal analysis. Lower integration and socialization with alcohol-using peers had immediate risks of binge drinking during adolescence; however, over time, the effects of socialization with alcohol-using peers had the most dramatic reduction. The most p...

  11. Examining the Relationship between Food Thought Suppression and Binge Eating Disorder

    OpenAIRE

    Barnes, Rachel D.; Masheb, Robin M.; White, Marney A.; Grilo, Carlos M.

    2013-01-01

    Food thought suppression, or purposely attempting to avoid thoughts of food, is related to a number of unwanted eating- and weight-related consequences, particularly in dieting and obese individuals. Little is known about the possible significance of food thought suppression in clinical samples, particularly obese patients who binge eat. This study examined food thought suppression in 150 obese patients seeking treatment for binge eating disorder (BED). Food thought suppression was not associ...

  12. Moderators of Post-Binge Eating Negative Emotion in Eating Disorders

    OpenAIRE

    De Young, Kyle P.; Lavender, Jason M.; Wonderlich, Stephen A.; Crosby, Ross D; Engel, Scott G.; Mitchell, James E; Crow, Scott; Peterson, Carol B.; le Grange, Daniel

    2012-01-01

    The purpose of this study was to test the impact of two variables on post-binge eating negative emotion in a combined sample of women with anorexia nervosa (AN; n = 47) and bulimia nervosa (BN; n = 121). Participants completed two weeks of an ecological momentary assessment protocol during which they provided multiple daily ratings of overall negative affect and guilt and reported eating disorder behaviors including binge eating and self-induced vomiting. The results indicate that both overal...

  13. Trajectories of Early Binge Drinking: A Function of Family Cohesion and Peer Use.

    Science.gov (United States)

    Soloski, Kristy L; Kale Monk, J; Durtschi, Jared A

    2016-01-01

    Using the National Longitudinal Study of Adolescent Health, we tested latent growth models examining whether the number of friends using alcohol and family cohesion were linked with trajectories of binge drinking (N = 3,342) from adolescence (average age 15.06) into young adulthood (average age 27.93). Adolescents with higher family cohesion had lower rates of binge drinking in adolescence (b = -.07, p Group Interventions as a potential approach. PMID:25585579

  14. The overlap between binge eating disorder and substance use disorders: Diagnosis and neurobiology

    OpenAIRE

    Schreiber, Liana R. N.; Odlaug, Brian L.; Grant, Jon E.

    2013-01-01

    Background and aims: Binge eating disorder (BED) is a relatively common condition, especially in young adult females, and is characterized by chronic over-consumption of food resulting in embarrassment, distress, and potential health problems. It is formally included as a disorder in DSM-5 for the first time, an acknowledgement to its debilitating nature. This article explores the overlap between binge eating disorder and substance use disorders (SUD). Methods: The bibliographic search was a ...

  15. Myocardial inflammation after binge drinking assessed by cardiac magnetic resonance imaging

    OpenAIRE

    Aiche, Sascha

    2011-01-01

    Background: Chronic alcohol abuse leads to inflammatory changes in myocardium. The aim of this study was to determine acute effects of excessive consumption of alcohol – binge drinking – and hangover on the heart especially in myocardium. We assumed that binge drinking leads to detectable changes in myocardium. Methods: Cardiac-MRI (CMR) was the diagnostic method. Evaluated parameters were T2-Ratio, relative enhancement, late enhancement and left ventricular function. Additionally humoral...

  16. Functional and structural brain connectivity of young binge drinkers: a follow-up study.

    Science.gov (United States)

    Correas, A; Cuesta, P; López-Caneda, E; Rodríguez Holguín, S; García-Moreno, L M; Pineda-Pardo, J A; Cadaveira, F; Maestú, F

    2016-01-01

    Adolescence is a period of ongoing brain maturation characterized by hierarchical changes in the functional and structural networks. For this reason, the young brain is particularly vulnerable to the toxic effects of alcohol. Nowadays, binge drinking is a pattern of alcohol consumption increasingly prevalent among adolescents. The aim of the present study is to evaluate the evolution of the functional and anatomical connectivity of the Default Mode Network (DMN) in young binge drinkers along two years. Magnetoencephalography signal during eyes closed resting state as well as Diffusion Tensor Imaging (DTI) were acquired twice within a 2-year interval from 39 undergraduate students (22 controls, 17 binge drinkers) with neither personal nor family history of alcoholism. The group comparison showed that, after maintaining a binge drinking pattern along at least two years, binge drinkers displayed an increased brain connectivity of the DMN in comparison with the control group. On the other hand, the structural connectivity did not show significant differences neither between groups nor over the time. These findings point out that a continued pattern of binge drinking leads to functional alterations in the normal brain maturation process, even before anatomical changes can be detected. PMID:27506835

  17. Functional and structural brain connectivity of young binge drinkers: a follow-up study

    Science.gov (United States)

    Correas, A.; Cuesta, P.; López-Caneda, E.; Rodríguez Holguín, S.; García-Moreno, L. M.; Pineda-Pardo, J. A.; Cadaveira, F.; Maestú, F.

    2016-01-01

    Adolescence is a period of ongoing brain maturation characterized by hierarchical changes in the functional and structural networks. For this reason, the young brain is particularly vulnerable to the toxic effects of alcohol. Nowadays, binge drinking is a pattern of alcohol consumption increasingly prevalent among adolescents. The aim of the present study is to evaluate the evolution of the functional and anatomical connectivity of the Default Mode Network (DMN) in young binge drinkers along two years. Magnetoencephalography signal during eyes closed resting state as well as Diffusion Tensor Imaging (DTI) were acquired twice within a 2-year interval from 39 undergraduate students (22 controls, 17 binge drinkers) with neither personal nor family history of alcoholism. The group comparison showed that, after maintaining a binge drinking pattern along at least two years, binge drinkers displayed an increased brain connectivity of the DMN in comparison with the control group. On the other hand, the structural connectivity did not show significant differences neither between groups nor over the time. These findings point out that a continued pattern of binge drinking leads to functional alterations in the normal brain maturation process, even before anatomical changes can be detected. PMID:27506835

  18. Investigating the moderating role of emotional awareness in the association between urgency and binge eating.

    Science.gov (United States)

    Manjrekar, Eishita; Berenbaum, Howard; Bhayani, Natasha

    2015-04-01

    Binge eating has been found to be associated with urgency (the tendency to act impulsively in response to negative affect) and emotional awareness (i.e., attention to emotions, clarity of emotions). The present study tested the hypothesis that the relation between binge eating and urgency would be moderated by emotional awareness, over and above negative affect. Participants were 249 female college students. Items from the Trait Meta Mood Scale (TMMS), the Urgency subscale of the UPPS Impulsive Behavior Scale, and the Bulimia (B) subscale of the Eating Disorders Inventory (EDI-3) were administered. As predicted, emotional awareness moderated the link between urgency and binge eating. Both Urgency×Attention to emotions and Urgency×Clarity of emotions significantly predicted binge eating scores, even after taking into account negative affect. Consistent with past research, higher levels of urgency were associated with higher levels of binge eating, even after taking negative affect into account. However, the associations were particularly strong among individuals with low levels of attention to emotions and low levels of clarity of emotions. The findings from this study have implications for future research examining binge eating. PMID:25679369

  19. Binge drinking impacts dorsal striatal response during decision making in adolescents.

    Science.gov (United States)

    Jones, Scott A; Cservenka, Anita; Nagel, Bonnie J

    2016-04-01

    Adolescence is a time of both increased risk taking and increased vulnerability to the neurotoxic effects of alcohol. However, it is unclear whether brain functioning abnormalities in adolescent binge drinkers are a result of alcohol use itself or whether they represent premorbid risk characteristics. The current study addresses this question by using a modified version of the Wheel of Fortune (WOF) task, during functional magnetic resonance imaging (fMRI), at both baseline, while all subjects were alcohol-naïve, and revisit, when half of the subjects had emerged into regular binge drinking (n=13) and half remained alcohol and substance-naïve (n=13). Region of interest (ROI) analysis revealed that during decision making, there was a significant binge-drinking related reduction in brain activation in the dorsal striatum, an effect associated with degree of recent use. Furthermore, whole-brain analysis revealed a decrease in fronto-parietal brain activation prior to initiation of alcohol use, in adolescents who went on to binge drink. Additionally, there were numerous regions, both cortical and subcortical, in which there was a significant time-related developmental change, across groups. These results demonstrate how abnormalities in decision-making related circuitry might both lead to and perpetuate alcohol drinking behavior. These findings help aid in our ability to disentangle consequences of binge drinking from potential risk markers for future binge drinking, and may help guide future prevention and intervention strategies. PMID:26826511

  20. Hourly temporal distribution of wind

    Science.gov (United States)

    Deligiannis, Ilias; Dimitriadis, Panayiotis; Koutsoyiannis, Demetris

    2016-04-01

    The wind process is essential for hydrometeorology and additionally, is one of the basic renewable energy resources. Most stochastic forecast models are limited up to daily scales disregarding the hourly scale which is significant for renewable energy management. Here, we analyze hourly wind timeseries giving emphasis on the temporal distribution of wind within the day. We finally present a periodic model based on statistical as well as hydrometeorological reasoning that shows good agreement with data. Acknowledgement: This research is conducted within the frame of the undergraduate course "Stochastic Methods in Water Resources" of the National Technical University of Athens (NTUA). The School of Civil Engineering of NTUA provided moral support for the participation of the students in the Assembly.

  1. Surgical treatment of double outlet ventricle: report on 72 cases

    Institute of Scientific and Technical Information of China (English)

    YANG Jin-fu; HU Dong-xu; HU Jian-guo; YIN Bang-liang; ZHOU Xin-min; ZHOU Wen-wu; TAN Si-chuang; YIN Ni

    2005-01-01

    @@ Double outlet ventricle (DOV) is defined as a congenital heart disease with: (1) both great arteries arising completely, or almost completely (≥90%), from a single ventricle (usually, right ventricle); (2) an aortic valve having no fibre connection with mitral valve; and (3) the only outlet of the other ventricle is a ventricular septal defect (VSD). The incidence of DOV accounts for 1% of all congenital heart disease.1 Clinically there are three common types: Fallot type or double outlet right ventricle (DORV) with subaortic VSD with pulmonary stenosis; Eisenmenger type or DORV with subaortic VSD without pulmonary stenosis and Taussig-Bing type or DORV with subpulmonary VSD. Operative techniques are different according to the position of the VSD and great arteries and the presence or absence of ventricular outflow tract obstruction. The operative difficulty increases in the presence of coronary artery malformation. Recently, our research centre has treated 72 cases of patients suffering from double outlet ventricle. This article is the report of the operative methods and the outcomes.

  2. OPENING HOURS FOR CARDS OFFICE

    CERN Multimedia

    Human Resources Division

    2001-01-01

    Due to the extra workload generated by the global renewal of French cards and in order to preserve the level of service offered by the cards office, please note that this office will in future be open every morning from 8.30 a.m. to 12.30 p.m. until further notice. The service can be contacted by telephone during the same hours. Thank you for your understanding.

  3. Social Participation and Hours Worked

    OpenAIRE

    Bartolini, Stefano; Bilancini, Ennio

    2011-01-01

    We investigate the relationship between social participation and the hours worked in the market. Social participation is the component of social capital that measures individuals? engagement in groups, associations and non-governmental organizations. We provide a model of consumer choice where social participation may be either a substitute or a complement to material consumption ? depending on whether participation is instrumentally or non-instrumentally motivated ? and where a local environ...

  4. Binge Drinking among 12-to-14-Year-Old Canadians: Findings from a Population-Based Study

    OpenAIRE

    Esme Fuller-Thomson; Tamara Grundland; Sheridan, Matthew P.; Cathy Sorichetti

    2014-01-01

    Purpose. This study’s objective is to document which factors are associated with binge drinking behaviour in a population-based sample of Canadian youth aged 12 to 14. Middle school is a key period in which binge drinking behaviour is initiated. Binge drinking is an important risk factor for alcohol-related injuries, accidental death, unsafe sexual behaviour, and substance abuse problems. Understanding the drinking patterns of this population can serve to better inform prevention programs and...

  5. Distinguishing Between Risk Factors for Bulimia Nervosa, Binge Eating Disorder, and Purging Disorder.

    Science.gov (United States)

    Allen, Karina L; Byrne, Susan M; Crosby, Ross D

    2015-08-01

    Binge eating disorder and purging disorder have gained recognition as distinct eating disorder diagnoses, but risk factors for these conditions have not yet been established. This study aimed to evaluate a prospective, mediational model of risk for the full range of binge eating and purging eating disorders, with attention to possible diagnostic differences. Specific aims were to determine, first, whether eating, weight and shape concerns at age 14 would mediate the relationship between parent-perceived childhood overweight at age 10 and a binge eating or purging eating disorder between age 15 and 20, and, second, whether this mediational model would differ across bulimia nervosa, binge eating disorder, and purging disorder. Participants (N = 1,160; 51 % female) were drawn from the Western Australian Pregnancy Cohort (Raine) Study, which has followed children from pre-birth to age 20. Eating disorders were assessed via self-report questionnaires when participants were aged 14, 17 and 20. There were 146 participants (82 % female) with a binge eating or purging eating disorder with onset between age 15 and 20 [bulimia nervosa = 81 (86 % female), binge eating disorder = 43 (74 % female), purging disorder = 22 (77 % female)]. Simple mediation analysis with bootstrapping was used to test the hypothesized model of risk, with early adolescent eating, weight and shape concerns positioned as a mediator between parent-perceived childhood overweight and later onset of a binge eating or purging eating disorder. Subsequently, a conditional process model (a moderated mediation model) was specified to determine if model pathways differed significantly by eating disorder diagnosis. In the simple mediation model, there was a significant indirect effect of parent-perceived childhood overweight on risk for a binge eating or purging eating disorder in late adolescence, mediated by eating, weight and shape concerns in early adolescence. In the conditional process model

  6. Distinguishing Between Risk Factors for Bulimia Nervosa, Binge Eating Disorder, and Purging Disorder.

    Science.gov (United States)

    Allen, Karina L; Byrne, Susan M; Crosby, Ross D

    2015-08-01

    Binge eating disorder and purging disorder have gained recognition as distinct eating disorder diagnoses, but risk factors for these conditions have not yet been established. This study aimed to evaluate a prospective, mediational model of risk for the full range of binge eating and purging eating disorders, with attention to possible diagnostic differences. Specific aims were to determine, first, whether eating, weight and shape concerns at age 14 would mediate the relationship between parent-perceived childhood overweight at age 10 and a binge eating or purging eating disorder between age 15 and 20, and, second, whether this mediational model would differ across bulimia nervosa, binge eating disorder, and purging disorder. Participants (N = 1,160; 51 % female) were drawn from the Western Australian Pregnancy Cohort (Raine) Study, which has followed children from pre-birth to age 20. Eating disorders were assessed via self-report questionnaires when participants were aged 14, 17 and 20. There were 146 participants (82 % female) with a binge eating or purging eating disorder with onset between age 15 and 20 [bulimia nervosa = 81 (86 % female), binge eating disorder = 43 (74 % female), purging disorder = 22 (77 % female)]. Simple mediation analysis with bootstrapping was used to test the hypothesized model of risk, with early adolescent eating, weight and shape concerns positioned as a mediator between parent-perceived childhood overweight and later onset of a binge eating or purging eating disorder. Subsequently, a conditional process model (a moderated mediation model) was specified to determine if model pathways differed significantly by eating disorder diagnosis. In the simple mediation model, there was a significant indirect effect of parent-perceived childhood overweight on risk for a binge eating or purging eating disorder in late adolescence, mediated by eating, weight and shape concerns in early adolescence. In the conditional process model

  7. Challenging the collegiate rite of passage: a campus-wide social marketing media campaign to reduce binge drinking.

    Science.gov (United States)

    Glider, P; Midyett, S J; Mills-Novoa, B; Johannessen, K; Collins, C

    2001-01-01

    A social marketing media campaign, based on a normative social influence model and focused on normative messages regarding binge drinking, on a large, southwestern university campus has yielded positive preliminary results of an overall 29.2 percent decrease in binge drinking rates over a three-year period. The Core Alcohol and Drug Survey and the Health Enhancement Survey provided information on student knowledge, perceptions, and behaviors regarding alcohol and binge drinking. This study represents the first in-depth research on the impact of a media approach, based on a normative social influence model, to reduce binge drinking on a large university campus and has yielded promising initial results. PMID:11487995

  8. Examining the effect of binge eating and disinhibition on compensatory changes in energy balance following exercise among overweight and obese women.

    Science.gov (United States)

    Emery, Rebecca L; Levine, Michele D; Jakicic, John M

    2016-08-01

    Some women behaviorally compensate for the energy expended during exercise by increasing their energy intake or becoming more sedentary, thereby decreasing their energy expenditure. Although behavioral compensation can attenuate or even reverse the energy deficit generated by exercise, few data are available on predictors of compensatory responses to exercise. The present study aimed to identify eating-related predictors of compensatory changes in energy balance following exercise. Overweight and obese, physically inactive women (N=48) completed self-report measures of disinhibition and binge eating and participated in two experimental conditions, exercise and rest, in counterbalanced order. Energy intake and expenditure were measured for 24-hours following each experimental condition to estimate energy balance. On average, women were 21.33±2.09years old and 63% were white. Of the sample, 63% compensated for the energy expended during exercise by increasing their energy intake or decreasing their energy expenditure. Linear mixed effects modeling with repeated measurement showed that disinhibition was not predictive of behavioral compensation. However, there was a significant difference between the negative energy balance observed following the rest condition and the positive energy balance observed following the exercise condition among women who reported binge eating, which was driven by a tendency to spend less time being physically active and more time being sedentary following exercise. These findings indicate that women who binge eat may be at greatest risk of compensating for exercise. Future research is needed to better understand psychosocial predictors and common mechanisms through which behavioral compensation is promoted. PMID:27064752

  9. Mechanisms of HSP72 release

    Indian Academy of Sciences (India)

    Alexzander Asea

    2007-04-01

    Currently two mechanisms are recognized by which heat shock proteins (HSP) are released from cells; a passive release mechanism, including necrotic cell death, severe blunt trauma, surgery and following infection with lytic viruses, and an active release mechanism which involves the non classical protein release pathway. HSPs are released both as free HSP and within exosomes. This review covers recent findings on the mechanism by which stress induces the release of HSP72 into the circulation and the biological significance of circulating HSP72 to host defense against disease.

  10. HTML5 24-Hour Trainer

    CERN Document Server

    Lowery, Joseph W

    2011-01-01

    Comprehensive written and interactive instruction for learning HTML5 HTML is the core technology for building websites. Today, with HTML5 opening the Internet to new levels of rich content and dynamic interactivity, developers are looking for information to learn and utilize HTML5. HTML5 24-Hour Trainer provides that information, giving new and aspiring web developers the knowledge they need to achieve early success when building websites. Covers the most basic aspects of a web page, including a brief introduction to Cascading Style Sheets (CSS) Provides lessons that are backed up by prof

  11. 24 Hours of Meaty Torture

    Institute of Scientific and Technical Information of China (English)

    Palesa; Temaswati; Mthethwa

    2011-01-01

    VEGETARIAN for a week! That was the plan.But it’s funny how side effects start kicking in so early when trying to let go of an everyday habit.The first morning of my experiment,I felt like I hadn’t eaten poultry in months(I had devoured a bucket of KFC the night before).Lunch was a disaster.I didn’t know whether to cook or spend an hour searching for a restaurant. That afternoon I received the worst phone call a first-time vegetarian can get:

  12. Java programming 24-hour trainer

    CERN Document Server

    Fain, Yakov

    2015-01-01

    Quick and painless Java programming with expert multimedia instruction Java Programming 24-Hour Trainer, 2nd Edition is your complete beginner's guide to the Java programming language, with easy-to-follow lessons and supplemental exercises that help you get up and running quickly. Step-by-step instruction walks you through the basics of object-oriented programming, syntax, interfaces, and more, before building upon your skills to develop games, web apps, networks, and automations. This second edition has been updated to align with Java SE 8 and Java EE 7, and includes new information on GUI b

  13. Binge drinking and blood pressure: cross-sectional results of the HAPIEE study.

    Directory of Open Access Journals (Sweden)

    Andrzej Pajak

    Full Text Available OBJECTIVES: To investigate whether binge drinking pattern influences blood pressure independently from drinking volume or whether it modifies the effect of volume of drinking. METHODS: We used cross-sectional data from population samples of 7559 men and 7471 women aged 45-69 years in 2002-05, not on antihypertensive medication, from Russia, Poland and Czech Republic. Annual alcohol intake, drinking frequency and binge drinking (≥ 100 g in men and ≥ 60 g in women in one session at least once a month were estimated from graduated frequency questionnaire. Blood pressure was analysed as continuous variables (systolic and diastolic pressure and a binary outcome (≥ 140/90 mm Hg. RESULTS: In men, annual alcohol intake and drinking frequency were strongly associated with blood pressure. The odds ratio of high blood pressure for binge drinking in men was 1.62 (95% CI 1.45-1.82 after controlling for age, country, body mass index, education and smoking; additional adjustment for annual alcohol intake reduced it to 1.20 (1.03-1.39. In women, the fully adjusted odds ratio of high blood pressure for binge drinking was 1.31 (1.05-1.63. Binge drinking did not modify the effect of annual alcohol intake. Consuming alcohol as wine, beer or spirits had similar effects. CONCLUSIONS: The results suggest that the independent long-term effect of binge drinking was modest, that binge drinking did not modify the effect of alcohol intake, and that different alcoholic beverages had similar effects on blood pressure.

  14. REGULATED BUSINESS HOURS, COMPETITION, AND LABOR UNIONS

    OpenAIRE

    Shy, Oz; Stenbacka, Rune

    2002-01-01

    We analyze a retail industry where shops compete in prices and opening hours. We demonstrate that stores with longer opening hours tend to charge higher prices. Then, we calculate the symmetric equilibrium in closing hours and demonstrate a market failure with opening hours shorter than the socially optimal level. Furthermore, we characterize a condition under which labor unions would set high wages that would limit opening hours below the equilibrium level. Thus, opening hours...

  15. Mood and forbidden foods' influence on perceptions of binge eating.

    Science.gov (United States)

    Guertin, T L; Conger, A J

    1999-01-01

    This study consists of two experiments investigating the effects of induced mood and food type on perceptions of eating in imagined and real eating situations. A total of 212 female undergraduates representing the continuum of bulimic symptomatology were induced with either elated or depressed moods using a standardized mood-induction procedure. They were then either asked to imagine themselves in a situation with either forbidden or non-forbidden foods (Experiment 1) or else were presented with a buffet of forbidden or non-forbidden foods and asked to eat (Experiment 2). Participants subsequently reported their perception of their eating behavior (i.e., amount of control, meal rating: from a snack to a binge; and meal feeling: from great to bad). Results revealed limited support for affect regulation models of bulimia nervosa when the participants consumed food, but no support for the theory when they imagined eating. Conversely, forbidden foods were found to influence perceptions in the imagined eating situation, but not when the participants ate. Implications of these results are discussed.

  16. Does Implicit Emotion Regulation in Binge Eating Disorder Matter?

    Science.gov (United States)

    Robinson, Athena; Safer, Debra L.; Austin, Julia L.; Etkin, Amit

    2015-01-01

    Objective To examine if implicit emotion regulation (occurring outside of awareness) is related to binge eating disorder (BED) symptomatology and explicit emotion regulation (occurring within awareness), and can be altered via intervention. Methods Implicit emotion regulation was assessed via the Emotion Conflict Task (ECT) among a group of adults with BED. Study 1 correlated BED symptomatology and explicit emotion regulation with ECT performance at baseline (BL) and after receiving BED treatment (PT). Study 2 generated effect sizes comparing ECT performance at BL and PT with healthy (non-eating disordered) controls (HC). Results Study 1 yielded significant correlations (p<.05) between both BED symptomatology and explicit emotion regulation with ECT performance. Study 2 found that compared to BL ECT performance, PT shifted (d=−.27), closer to HC. Preliminary results suggest a) BED symptomatology and explicit emotion regulation are associated with ECT performance, and b) PT ECT performance normalized after BED treatment. Conclusions Implicit emotion regulation may be a BED treatment mechanism because psychotherapy, directly or indirectly, decreased sensitivity to implicit emotional conflict. Further understanding implicit emotion regulation may refine conceptualizations and effective BED treatments. PMID:26117164

  17. BingEO: Enable Distributed Earth Observation Data for Environmental Research

    Science.gov (United States)

    Wu, H.; Yang, C.; Xu, Y.

    2010-12-01

    Our planet is facing great environmental challenges including global climate change, environmental vulnerability, extreme poverty, and a shortage of clean cheap energy. To address these problems, scientists are developing various models to analysis, forecast, simulate various geospatial phenomena to support critical decision making. These models not only challenge our computing technology, but also challenge us to feed huge demands of earth observation data. Through various policies and programs, open and free sharing of earth observation data are advocated in earth science. Currently, thousands of data sources are freely available online through open standards such as Web Map Service (WMS), Web Feature Service (WFS) and Web Coverage Service (WCS). Seamless sharing and access to these resources call for a spatial Cyberinfrastructure (CI) to enable the use of spatial data for the advancement of related applied sciences including environmental research. Based on Microsoft Bing Search Engine and Bing Map, a seamlessly integrated and visual tool is under development to bridge the gap between researchers/educators and earth observation data providers. With this tool, earth science researchers/educators can easily and visually find the best data sets for their research and education. The tool includes a registry and its related supporting module at server-side and an integrated portal as its client. The proposed portal, Bing Earth Observation (BingEO), is based on Bing Search and Bing Map to: 1) Use Bing Search to discover Web Map Services (WMS) resources available over the internet; 2) Develop and maintain a registry to manage all the available WMS resources and constantly monitor their service quality; 3) Allow users to manually register data services; 4) Provide a Bing Maps-based Web application to visualize the data on a high-quality and easy-to-manipulate map platform and enable users to select the best data layers online. Given the amount of observation data

  18. Integrated smoking cessation and binge drinking intervention for young adults: a pilot efficacy trial.

    Science.gov (United States)

    Ames, Steven C; Pokorny, Steven B; Schroeder, Darrell R; Tan, Winston; Werch, Chudley E

    2014-05-01

    Alcohol consumption is strongly associated with cigarette smoking in young adults. The primary aim of this investigation was to complete a pilot evaluation of the efficacy of an integrated intervention that targets both cigarette smoking and binge drinking on the cigarette smoking and binge behavior of young adults at 6-month follow-up. Participants were 95 young adult (M=24.3; SD=3.5 years) smokers (≥1 cigarettes per day) who binge drink (≥1 time per month) and who were randomly assigned to standard treatment (n=47) involving six individual treatment visits plus eight weeks of nicotine patch therapy or the identical smoking cessation treatment integrated with a binge drinking intervention (integrated intervention; n=48). Using an intent-to-treat analysis for tobacco abstinence, at both 3 month end of treatment and 6 month follow-up, more participants who received integrated intervention were biochemically confirmed abstinent from tobacco than those who received standard treatment at 3 months (19% vs. 9%, p=0.06) and 6 months (21% vs. 9%, p=0.05). At 6 months, participants who completed the study and who received integrated intervention consumed fewer drinks per month (psmoking cessation and reduces binge drinking compared to standard treatment.

  19. Enhanced striatal dopamine release during food stimulation in binge eating disorder

    International Nuclear Information System (INIS)

    Subjects with binge eating disorder (BED) regularly consume large amounts of food in short time periods. The neurobiology of BED is poorly understood. Brain dopamine, which regulates motivation for food intake, is likely to be involved. We assessed the involvement of brain dopamine in the motivation for food consumption in binge eaters. Positron emission tomography (PET) scans with [11C]raclopride were done in 10 obese BED and 8 obese subjects without BED. Changes in extracellular dopamine in the striatum in response to food stimulation in food-deprived subjects were evaluated after placebo and after oral methylphenidate (MPH), a drug that blocks the dopamine reuptake transporter and thus amplifies dopamine signals. Neither the neutral stimuli (with or without MPH) nor the food stimuli when given with placebo increased extracellular dopamine. The food stimuli when given with MPH significantly increased dopamine in the caudate and putamen in the binge eaters but not in the nonbinge eaters. Dopamine increases in the caudate were significantly correlated with the binge eating scores but not with BMI. These results identify dopamine neurotransmission in the caudate as being of relevance to the neurobiology of BED. The lack of correlation between BMI and dopamine changes suggests that dopamine release per se does not predict BMI within a group of obese individuals but that it predicts binge eating.

  20. URB597 inhibits oxidative stress induced by alcohol binging in the prefrontal cortex of adolescent rats.

    Science.gov (United States)

    Pelição, Renan; Santos, Matheus C; Freitas-Lima, Leandro C; Meyrelles, Silvana S; Vasquez, Elisardo C; Nakamura-Palacios, Ester M; Rodrigues, Lívia C M

    2016-06-15

    Heavy episodic drinking (binging), which is highly prevalent among teenagers, results in oxidative damage. Because the prefrontal cortex (PFC) is not completely mature in adolescents, this brain region may be more vulnerable to the effects of alcohol during adolescence. As endocannabinoids may protect the immature PFC from the harmful effects of high doses of alcohol, this study investigated the effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597 on oxidative stress induced by acute or chronic binge alcohol intake in adolescent rats. At 40min after intraperitoneal pre-treatment with URB597 (0.3mg/kg) or vehicle (Veh), ethanol (EtOH; 3 or 6g/kg, intragastrically) or distilled water (DW) was administered in 3 consecutive sessions (acute binging) or 3 consecutive sessions over 4 weeks (chronic binging). Oxidative stress in PFC slices in situ was measured by dihydroethidium fluorescence staining. At the higher EtOH dose (6g/kg), pre-treatment with URB597 significantly reduced (peffect of endocannabinoids to suppress acute and chronic binge alcohol intake-induced oxidative stress in the PFC of adolescent rats. PMID:27150075

  1. Enhanced striatal dopamine release during food stimulation in binge eating disorder

    Energy Technology Data Exchange (ETDEWEB)

    Wang, g.j.; Wang, G.-J.; Geliebter, A.; Volkow, N.D.; Telang, F.W.; Logan, Jaynbe, M.C.; Galanti, K.; Selig, P.A.; Han, H.; Zhu, W.; Wong, C.T.; Fowler, J.S.

    2011-01-13

    Subjects with binge eating disorder (BED) regularly consume large amounts of food in short time periods. The neurobiology of BED is poorly understood. Brain dopamine, which regulates motivation for food intake, is likely to be involved. We assessed the involvement of brain dopamine in the motivation for food consumption in binge eaters. Positron emission tomography (PET) scans with [{sup 11}C]raclopride were done in 10 obese BED and 8 obese subjects without BED. Changes in extracellular dopamine in the striatum in response to food stimulation in food-deprived subjects were evaluated after placebo and after oral methylphenidate (MPH), a drug that blocks the dopamine reuptake transporter and thus amplifies dopamine signals. Neither the neutral stimuli (with or without MPH) nor the food stimuli when given with placebo increased extracellular dopamine. The food stimuli when given with MPH significantly increased dopamine in the caudate and putamen in the binge eaters but not in the nonbinge eaters. Dopamine increases in the caudate were significantly correlated with the binge eating scores but not with BMI. These results identify dopamine neurotransmission in the caudate as being of relevance to the neurobiology of BED. The lack of correlation between BMI and dopamine changes suggests that dopamine release per se does not predict BMI within a group of obese individuals but that it predicts binge eating.

  2. Enhanced striatal dopamine release during food stimulation in binge eating disorder.

    Science.gov (United States)

    Wang, Gene-Jack; Geliebter, Allan; Volkow, Nora D; Telang, Frank W; Logan, Jean; Jayne, Millard C; Galanti, Kochavi; Selig, Peter A; Han, Hao; Zhu, Wei; Wong, Christopher T; Fowler, Joanna S

    2011-08-01

    Subjects with binge eating disorder (BED) regularly consume large amounts of food in short time periods. The neurobiology of BED is poorly understood. Brain dopamine, which regulates motivation for food intake, is likely to be involved. We assessed the involvement of brain dopamine in the motivation for food consumption in binge eaters. Positron emission tomography (PET) scans with [(11)C]raclopride were done in 10 obese BED and 8 obese subjects without BED. Changes in extracellular dopamine in the striatum in response to food stimulation in food-deprived subjects were evaluated after placebo and after oral methylphenidate (MPH), a drug that blocks the dopamine reuptake transporter and thus amplifies dopamine signals. Neither the neutral stimuli (with or without MPH) nor the food stimuli when given with placebo increased extracellular dopamine. The food stimuli when given with MPH significantly increased dopamine in the caudate and putamen in the binge eaters but not in the nonbinge eaters. Dopamine increases in the caudate were significantly correlated with the binge eating scores but not with BMI. These results identify dopamine neurotransmission in the caudate as being of relevance to the neurobiology of BED. The lack of correlation between BMI and dopamine changes suggests that dopamine release per se does not predict BMI within a group of obese individuals but that it predicts binge eating.

  3. Food thought suppression: a matched comparison of obese individuals with and without binge eating disorder.

    Science.gov (United States)

    Barnes, Rachel D; Masheb, Robin M; Grilo, Carlos M

    2011-12-01

    Preliminary studies of non-clinical samples suggest that purposely attempting to avoid thoughts of food, referred to as food thought suppression, is related to a number of unwanted eating- and weight-related consequences, particularly in obese individuals. Despite possible implications for the treatment of obesity and eating disorders, little research has examined food thought suppression in obese individuals with binge eating disorder (BED). This study compared food thought suppression in 60 obese patients with BED to an age-, gender-, and body mass index (BMI)-matched group of 59 obese persons who do not binge eat (NBO). In addition, this study examined the associations between food thought suppression and eating disorder psychopathology within the BED and NBO groups and separately by gender. Participants with BED and women endorsed the highest levels of food thought suppression. Food thought suppression was significantly and positively associated with many features of ED psychopathology in NBO women and with eating concerns in men with BED. Among women with BED, higher levels of food thought suppression were associated with higher frequency of binge eating, whereas among men with BED, higher levels of food thought suppression were associated with lower frequency of binge eating. Our findings suggest gender differences in the potential significance of food thought suppression in obese groups with and without co-existing binge eating problems.

  4. Binge-pattern alcohol exposure during puberty induces long-term changes in HPA axis reactivity.

    Directory of Open Access Journals (Sweden)

    Magdalena M Przybycien-Szymanska

    Full Text Available Adolescence is a dynamic and important period of brain development however, little is known about the long-term neurobiological consequences of alcohol consumption during puberty. Our previous studies showed that binge-pattern ethanol (EtOH treatment during pubertal development negatively dysregulated the responsiveness of the hypothalamo-pituitary-adrenal (HPA axis, as manifested by alterations in corticotrophin-releasing hormone (CRH, arginine vasopressin (AVP, and corticosterone (CORT during this time period. Thus, the primary goal of this study was to determine whether these observed changes in important central regulators of the stress response were permanent or transient. In this study, juvenile male Wistar rats were treated with a binge-pattern EtOH treatment paradigm or saline alone for 8 days. The animals were left undisturbed until adulthood when they received a second round of treatments consisting of saline alone, a single dose of EtOH, or a second binge-pattern treatment paradigm. The results showed that pubertal binge-pattern EtOH exposure induced striking long-lasting alterations of many HPA axis parameters. Overall, our data provide strong evidence that binge-pattern EtOH exposure during pubertal maturation has long-term detrimental effects for the healthy development of the HPA axis.

  5. Alcohol binging causes peliosis hepatis during azathioprine therapy in Crohn's disease

    Institute of Scientific and Technical Information of China (English)

    Christoph Elsing; Joerg Placke; Thomas Herrmann

    2007-01-01

    Patients with inflammatory bowel disease have normal life expectancy and, due to modern immunosuppressive therapies, also a normal quality of life. Since mostly young people are affected, their social behaviour suits this environment. Alcohol binging is an increasingly disturbing factor among young people. We describe a patient with Crohn's disease, treated with azathioprine,who developed peliosis hepatis after three epsiodes of alcohol binging. Liver toxicity was not observed previously during the course of the treatment.Azathioprine-induced peliosis hepatis is thought to be idiosyncratic in humans. From animal studies, however,it is clear that hepatic depletion of glutathione leads to azathioprine toxicity to the sinusoidal endothelial cells. Damage of these cells causes peliosis hepatis.Since alcohol binging leads to hepatic glutathione depletion, we conclude that in our patient the episodes of binging have reduced liver gluathione content and therefore this has increased azathioprine toxicity causing peliosis hepatis. The problem of alcohol binging has not yet been addressed in IBD patients undertaking immunosuppressive therapy. This should be reviewed in future considerations regarding patients advice.

  6. Effects of resistance training on binge eating, body composition and blood variables in type II diabetics

    Directory of Open Access Journals (Sweden)

    Moisés Simão Santa Rosa de Sousa

    2014-03-01

    This study examined the effects of 12 weeks of resistance training (RT on binge eating, body composition and blood variables and their correlations in 34 sedentary adults with type II diabetes. The participants aged 58.94 ± 10.66, had body weight of 71.62 ± 11.85 and BMI of 29.64 ± 4.27. Blood samples were collected for analysis of serum leptin, glucose, insulin, LDL, HDL, total cholesterol and triglyceride. The binge eating was assessed by the binge eating scale and the body composition by bioelectrical impedance. The training included three weekly sessions for 12 weeks, with three sets from 12 to 15 repetitions for the main muscle groups, and interval from 1 to 2 minutes between the sets. A significant decrease was found for the binge eating, body weight, BMI, fat percentage, and fat weight. As for the blood variables, there was a significant reduction in leptin; non-significant reductions in glucose, total cholesterol, LDL and triglycerides; as well a significant increase in HDL and non-significant increase in insulin. In conclusion the 12 weeks of RT proved to be enough to decrease the binge eating, to positively adjust the body composition and to modify the blood profile, demonstrating an association at a lower or higher level between these variables.

  7. A Cognitive-Behavioral Mindfulness Group Therapy Intervention for the Treatment of Binge Eating in Bariatric Surgery Patients

    Science.gov (United States)

    Leahey, Tricia M.; Crowther, Janis H.; Irwin, Sharon R.

    2008-01-01

    Binge eating is a negative indicator of post-surgical weight loss and health outcome in bariatric surgery patients (Hsu, Bentancourt, Sullivan, 1996). Cognitive-behavioral techniques and mindfulness-based practices have been shown to successfully treat binge eating (Agras, Telch, Arnow, Eldredge, & Marnell, 1997; Kristeller & Hallett, 1999). This…

  8. Challenging the Collegiate Rite of Passage: A Campus-Wide Social Marketing Media Campaign To Reduce Binge Drinking.

    Science.gov (United States)

    Glider, Peggy; Midyett, Stephen J.; Mills-Novoa, Beverly; Johannessen, Koreen; Collins, Carolyn

    2001-01-01

    A social marketing media campaign, based on a normative social influence model and focused on normative messages regarding binge drinking, has yielded positive preliminary results of an overall 29.2 percent decrease in binge drinking rates over a three-year period. Two surveys provided information on student knowledge, perceptions, and behaviors…

  9. Zonisamide Combined with Cognitive Behavioral Therapy in Binge Eating Disorder: A One-year Follow-up Study

    OpenAIRE

    Ricca, Valdo; Castellini, Giovanni; Lo Sauro, Carolina; Rotella, Carlo M.; Faravelli, Carlo

    2009-01-01

    Objective. Binge eating disorder is a serious, prevalent eating disorder that is associated with overweight. Zonisamide is an antiepileptic drug that can promote weight loss. We evaluated the efficacy and safety of zonisamide as augmentation to individual cognitive behavioral therapy in the treatment of binge eating disorder patients.

  10. The Moderating Role of Father's Care on the Onset of Binge Eating Symptoms among Female Late Adolescents with Insecure Attachment

    Science.gov (United States)

    Pace, Ugo; Cacioppo, Marco; Schimmenti, Adriano

    2012-01-01

    The present study examined the association between quality of attachment, perception of the father's bond, and binge eating symptoms in a sample of female late adolescents. In total, 233 female students aged between 18 and 20 years completed measures on binge eating, quality of attachment and parent-child relationship. Data showed that respondents…

  11. Reformulating and Testing the Perfectionism Model of Binge Eating among Undergraduate Women: A Short-Term, Three-Wave Longitudinal Study

    Science.gov (United States)

    Mackinnon, Sean P.; Sherry, Simon B.; Graham, Aislin R.; Stewart, Sherry H.; Sherry, Dayna L.; Allen, Stephanie L.; Fitzpatrick, Skye; McGrath, Daniel S.

    2011-01-01

    The perfectionism model of binge eating (PMOBE) is an integrative model explaining why perfectionism is related to binge eating. This study reformulates and tests the PMOBE, with a focus on addressing limitations observed in the perfectionism and binge-eating literature. In the reformulated PMOBE, concern over mistakes is seen as a destructive…

  12. Induction of Heat Shock Protein 72 in RGCs of Rat Acute Glaucoma Model after Heat Stress or Zinc Administration

    Institute of Scientific and Technical Information of China (English)

    Guoping Qing; Xuanchu Duan; Youqin Jiang

    2004-01-01

    Purpose :To investigate the dynamics of heat shock protein 72 (HSP72) expression in retinal ganglion cells (RGCs) in rat model of acute glaucoma treated with heat stress or intraperitoneal injection of zinc sulfate.Methods: Twenty-seven male Wistar rats were used to make acute glaucoma models. Five others served as normal control. Acute glaucoma models were made by intracameral irrigation in the right eyes with balanced salt saline (BSS) at 102 mmHg for 2 hours. Nine model rats were killed at different intervals after intracameral irrigation without treatment, which served as damage control. Ten were treated with heat stress 40℃~42℃, and 8 were used for zinc sulfate administration 2 days posterior to intracameral irrigation.Treated model rats were sacrificed at designed intervals after treatment. Right eyes were enucleated immediately, and the retinas were dissected for Western blot.Results: No HSP72 was found in RGCs of normal Wistar rats. In damage control group,slight HSP72 was detected during 6~36 hours posterior to intracameral irrigation. HSP72was detected significantly expressed in RGCs of both heat shock group and zinc sulfate group. But the dynamics of HSP72 production were quite different in these two treated groups. In heat shock group, HSP72 appeared at the sixth hour after treatment, and increased gradually until its peak production emerged at the 48th hour. HSP72 vanished 8days later after treatment. In zinc sulfate group, HSP72 expression began 24 hours later after zinc administration, and reached its highest level at the 72th hour posterior to treatment. HSP72 expression then decreased slowly, and disappeared 21 days later after treatment.Conclusion:HSP72 can be induced in RGCs of rat acute glaucoma models with heat stress or zinc sulfate adddministration. But the dynamics of the HSP72 induction in those two groups were quite different. Eye Science 2004;20:30-33.

  13. 10 CFR 72.72 - Material balance, inventory, and records requirements for stored materials.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Material balance, inventory, and records requirements for stored materials. 72.72 Section 72.72 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING...-RELATED GREATER THAN CLASS C WASTE Records, Reports, Inspections, and Enforcement § 72.72 Material...

  14. Mindfulness meditation as an intervention for binge eating, emotional eating, and weight loss: a systematic review.

    Science.gov (United States)

    Katterman, Shawn N; Kleinman, Brighid M; Hood, Megan M; Nackers, Lisa M; Corsica, Joyce A

    2014-04-01

    Mindfulness-based approaches are growing in popularity as interventions for disordered eating and weight loss. Initial research suggests that mindfulness meditation may be an effective intervention for binge eating; however, no systematic review has examined interventions where mindfulness meditation was the primary intervention and no review has examined its effect on subclinical disordered eating or weight. Using the PRISMA method for systematic reviews, we reviewed 14 studies that investigated mindfulness meditation as the primary intervention and assessed binge eating, emotional eating, and/or weight change. Results suggest that mindfulness meditation effectively decreases binge eating and emotional eating in populations engaging in this behavior; evidence for its effect on weight is mixed. Additional research is warranted to determine comparative effectiveness and long-term effects of mindfulness training.

  15. Adding mindfulness to CBT programs for binge eating: a mixed-methods evaluation.

    Science.gov (United States)

    Woolhouse, Hannah; Knowles, Ann; Crafti, Naomi

    2012-01-01

    The current study investigated the effectiveness of a combined mindfulness-CBT group therapy program for women with binge eating problems. Questionnaires were completed by group participants pre-program (n = 30), post-program (n = 30) and 3 month follow-up (n = 28). Significant reductions between pre- and post-program scores were found on standardised measures assessing binge eating, dieting, and body image dissatisfaction, with all reductions maintained at follow-up. Qualitative interviews with 16 women following completion of the program revealed the value of mindfulness in improving eating behaviour through increased self-awareness. This exploratory study supports the value of adding mindfulness to the more commonly utilised CBT-based programs for binge eating.

  16. Understanding experiences and outcomes in treatment of binge eating disorder and obesity: A mixed method study

    DEFF Research Database (Denmark)

    Meyer, Lene; Tjørnhøj-Thomsen, Tine; Lau, Marianne Engelbrecht;

    Background: Binge eating disorder (BED) has recently been recognized as a diagnosis in the DSM-5 (Diagnostic Manual of Mental Disorders). BED is a severe eating disorder with physical, social and psychological consequences. The prevalence of BED is 2-3% and the majority develop weight problems...... and obesity. Treatment is found effective in reducing eating disorder symptomatology, but rarely leads to weight loss. It is still unknown how the issue of obesity can be addressed in BED treatment without increasing the risk of binge eating relapse. Objectives: The study is an explorative investigation...... of the outcome of a newly developed group based treatment that combines psychotherapy and either weight loss or well-being components for patients with binge eating disorders and obesity. Methods: The study uses a convergent mixed methods design. Qualitative and quantitative data are gathered using in...

  17. Stemming Mechanism of Search Engine Bing For Single-Plural Words

    Directory of Open Access Journals (Sweden)

    Fatmana Şentürk

    2014-02-01

    Full Text Available Today, it has become really fast and easy to access information thanks to the developments in the internet world. Search engines have been developed to find desired information in this gigantic internet world. It is important to know how these search engines works so that searches are more efficient. This work provides results that could help end-users to access information faster. It could also help researchers to interpret results, provided by search engines, better. In this work we have tried to find the indexing algorithm of Bing for single-plural words. For this purpose, we first selected the suitable words and then send the constructed queries to the Bing. Afterwards, the returned results of the queries had been analyzed. We found out that there is a strong relation between single and plural form of the words in term of indexing by Bing. In addition, the frequencies of usage of the words also effect this relation.

  18. Dieting in bulimia nervosa is associated with increased food restriction and psychopathology but decreased binge eating.

    Science.gov (United States)

    Lowe, Michael R; Witt, Ashley A; Grossman, Stephanie L

    2013-08-01

    The cognitive behavioral model of bulimia nervosa (BN) suggests that dieting is central to the maintenance of binge eating. However, correlational and experimental studies suggest that additional clarification is needed about the nature of this relationship. Dieting, weight, eating disorder psychopathology, and depression were assessed at admission among 166 patients with BN presenting for residential treatment. As in past research, a significant fraction (43%) of patients with BN reported not currently dieting. A comparison of weight loss dieters and non-dieters found greater food restriction and eating disorder psychopathology among weight loss dieters. However, dieters reported less frequent binge eating. There were no significant group differences in depression. Results suggest that 1) while many individuals with BN are attempting to restrict their food intake, the goal of losing weight fundamentally alters the effect of such restriction on binge eating, and 2) treatment may benefit from helping patients to establish a healthier approach to achieving long-term weight stability.

  19. Post-Editing Error Correction Algorithm for Speech Recognition using Bing Spelling Suggestion

    CERN Document Server

    Bassil, Youssef

    2012-01-01

    ASR short for Automatic Speech Recognition is the process of converting a spoken speech into text that can be manipulated by a computer. Although ASR has several applications, it is still erroneous and imprecise especially if used in a harsh surrounding wherein the input speech is of low quality. This paper proposes a post-editing ASR error correction method and algorithm based on Bing's online spelling suggestion. In this approach, the ASR recognized output text is spell-checked using Bing's spelling suggestion technology to detect and correct misrecognized words. More specifically, the proposed algorithm breaks down the ASR output text into several word-tokens that are submitted as search queries to Bing search engine. A returned spelling suggestion implies that a query is misspelled; and thus it is replaced by the suggested correction; otherwise, no correction is performed and the algorithm continues with the next token until all tokens get validated. Experiments carried out on various speeches in differen...

  20. Binge Eating Disorder and Medical Comorbidities in Bariatric Surgery Candidates

    Science.gov (United States)

    Mitchell, James E.; King, Wendy C.; Pories, Walter; Wolfe, Bruce; Flum, David R.; Spaniolas, Konstatinos; Bessler, Mark; Devlin, Michael; Marcus, Marsha D.; Kalarchian, Melissa; Engel, Scott; Khandelwal, Saurobh; Yanovski, Susan

    2016-01-01

    Objective To determine whether binge eating disorder (BED) status is associated with medical comorbidities in obese adults scheduled for bariatric surgery. Method The study utilized Longitudinal Assessment of Bariatric Surgery-2 data obtained from 6 clinical centers around the United States. This is a well-phenotyped cohort of individuals who were evaluated within 30 days prior to their scheduled surgery using standardized protocols. In the cohort, 350 participants were classified as having BED and 1875 as not having BED (non-BED). Multivariable logistic regression was used to determine whether BED status was independently related to medical comorbidities. As an exploratory analysis, significance was based on nominal P-values (p<.05). Holm-adjusted P-values were also reported. Results After adjusting for age, sex, education and body mass index, BED status was independently associated with 4 of 15 comorbidities (i.e., impaired glucose levels (odds ratio [OR]=1.45 (95%CI: 1.12–1.87), high triglycerides (OR=1.28 (95%CI: 1.002–1.63) and urinary incontinence (OR=1.30 (95%CI: 1.02,1.66) all being more common among the BED sample, and severe walking limitations being less common in the BED sample (OR=0.53 (95%CI: 0.29–0.96)). With further adjustment for psychiatric/emotional health indicators, BED status was independently associated with 3 comorbidities (impaired glucose levels (OR=1.36 (95%CI: 1.04–1.79), cardiovascular disease (OR=0.50 (95%CI: 0.30–0.86) and severe walking limitations (OR=0.38 (95%CI: 0.19–0.77)). However, Holm’s adjusted P-values for all variables were greater than .05. Discussion The results suggest the possibility of a contribution of BED to risk of specific medical comorbidities in severely obese adults. PMID:25778499

  1. Binge eating & childhood emotional abuse: The mediating role of anger.

    Science.gov (United States)

    Feinson, Marjorie C; Hornik-Lurie, Tzipi

    2016-10-01

    Recent studies reveal that childhood emotional abuse (CEA) is the trauma most clearly associated with adult eating pathology. Yet, relatively little is understood about psychological mechanisms linking these distal experiences. Anger's mediational role in the relationship between CEA and adult binge eating (BE) is explored in a community-based sample of 498 adult women (mean age 44). Detailed telephone interviews assess BE (7 items), CEA (single item), and unresolved anger (single item) along with self-criticism (modified Rosenberg self-esteem scale), depression and anxiety symptoms (BSI sub-scales). Statistical analyses include Pearson correlations, Baron and Kenny's steps for mediation, and Preacher and Hayes bootstrapping method to test proposed multiple mediators simultaneously. Findings reveal significantly more respondents (n = 476 with complete data) with serious BE behaviors report a history of CEA compared to women with considerable and/or minimal BE (53% vs 37%, p = 0.002 respectively). Significant correlations are found among all study variables. Mediation analyses focus on anger together with self-criticism, depression and anxiety. Findings reveal anger and self-criticism fully mediate the CEA-BE relationship. In contrast, depression and anxiety symptoms are not significant mediators in a model that includes anger and self-criticism. Although additional research is warranted to more fully understand complex causal processes, in the interim, treatment interventions should be broadened to include assessments of anger among adult women with BE behaviors, especially those with histories of childhood abuse. Additionally, prevention strategies that incorporate learning how to express anger directly and positively may be particularly effective in reducing various disordered eating behaviors among women and girls. PMID:27208594

  2. Executive performance and dysexecutive symptoms in binge drinking adolescents.

    Science.gov (United States)

    Gil-Hernandez, Soledad; Garcia-Moreno, Luis M

    2016-03-01

    Alcohol is probably the most common legal drug of abuse in Western countries. The prevalence of binge drinking (BD) pattern of alcohol consumption among adolescents is a worrisome phenomenon. Adolescents and university students who practice a BD pattern have difficulty performing tasks involving prefrontal cortex functions, such as working memory, planning, attention, and decision making. The aim of the present study was to investigate the association between BD and executive functioning in adolescents. Two hundred twenty-three high-school students between 12 and 18 years old (15.19 ± 2.13) participated in our study. They were assigned to one of three groups according to their pattern of alcohol consumption: BD (subjects who consumed alcohol intensively, n = 48), MAC (subjects who consumed alcohol moderately, n = 53), and CTR (non-drinking subjects, n = 122). The students were evaluated with two groups of testing tools: a set of performance neuropsychological tests and two questionnaires of executive functioning. The results showed that the students who drank alcohol exhibited a more pronounced dysexecutive symptomatology (disinhibition, executive dysfunction, intentionality, executive memory), but they obtained better results than controls on some of the neuropsychological tests such as Spatial Location, Five Digit Tests, or Stroop Test. According to the results, we can deduce that heavy alcohol drinking in adolescents brings a certain dysfunction of prefrontal circuits. This prefrontal dysfunction is not so clearly demonstrated in the neuropsychological tests used, but it was observed in the performance of daily activities. In the Discussion section we raise issues about sociodemographic features of the sample and ecological validity of the traditional neuropsychological tests. The neurotoxic effects of BD on prefrontal cortex can be less evident throughout adolescence, but if alcohol consumption persists, the executive dysfunction would be exacerbated

  3. Impaired respiratory function and heightened pulmonary inflammation in episodic binge ethanol intoxication and burn injury.

    Science.gov (United States)

    Shults, Jill A; Curtis, Brenda J; Chen, Michael M; O'Halloran, Eileen B; Ramirez, Luis; Kovacs, Elizabeth J

    2015-11-01

    Clinical data indicate that cutaneous burn injuries covering greater than 10% of the total body surface area are associated with significant morbidity and mortality, in which pulmonary complications, including acute respiratory distress syndrome (ARDS), contribute to nearly half of all patient deaths. Approximately 50% of burn patients are intoxicated at the time of hospital admission, which increases days on ventilators by 3-fold, and doubles the length of hospitalization, compared to non-intoxicated burn patients. The most common drinking pattern in the United States is binge drinking, where an individual rapidly consumes alcoholic beverages (4 for women, 5 for men) in 2 h. An estimated 38 million Americans binge drink, often several times per month. Experimental data demonstrate that a single binge-ethanol exposure, prior to scald injury, impairs innate and adaptive immune responses, thereby enhancing infection susceptibility and amplifying pulmonary inflammation, neutrophil infiltration, and edema, and is associated with increased mortality. Since these characteristics are similar to those observed in ARDS burn patients, our study objective was to determine whether ethanol intoxication and burn injury and the subsequent pulmonary congestion affect physiological parameters of lung function, using non-invasive and unrestrained plethysmography in a murine model system. Furthermore, to mirror young adult binge-drinking patterns, and to determine the effect of multiple ethanol exposures on pulmonary inflammation, we utilized an episodic binge-ethanol exposure regimen, where mice were exposed to ethanol for a total of 6 days (3 days ethanol, 4 days rest, 3 days ethanol) prior to burn injury. Our analyses demonstrate mice exposed to episodic binge ethanol and burn injury have higher mortality, increased pulmonary congestion and neutrophil infiltration, elevated neutrophil chemoattractants, and respiratory dysfunction, compared to burn or ethanol intoxication alone

  4. 36 CFR 72.71 - Information collection.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Information collection. 72.71... PARK AND RECREATION RECOVERY ACT OF 1978 Post-Completion Compliance Responsibilities § 72.71 Information collection. The information collection requirements contained in § 72.72 have been approved by...

  5. Mindfulness-Action Based Cognitive Behavioral Therapy for concurrent Binge Eating Disorder and Substance Use Disorders.

    Science.gov (United States)

    Courbasson, Christine M; Nishikawa, Yasunori; Shapira, Leah B

    2011-01-01

    Individuals with Binge Eating Disorder (BED) often evidence comorbid Substance Use Disorders (SUD), resulting in poor outcome. This study is the first to examine treatment outcome for this concurrent disordered population. In this pilot study, 38 individuals diagnosed with BED and SUD participated in a 16-week group Mindfulness-Action Based Cognitive Behavioral Therapy (MACBT). Participants significantly improved on measures of objective binge eating episodes; disordered eating attitudes; alcohol and drug addiction severity; and depression. Taken together, MACBT appears to hold promise in treating individuals with co-existing BED-SUD.

  6. Predictors of binge drinking in adolescents: ultimate and distal factors - a representative study

    Directory of Open Access Journals (Sweden)

    Donath Carolin

    2012-04-01

    Full Text Available Abstract Background As epidemiological surveys have shown, binge drinking is a constant and wide-spread problem behavior in adolescents. It is not rare to find that more than half of all adolescents engage in this behavior when assessing only the last 4 weeks of time independent of the urbanity of the region they live in. There have been several reviews on predictors of substance consumption in adolescents in general, but there has been less high quality research on predictors of binge drinking, and most studies have not been theoretically based. The current study aimed to analyze the ultimate and distal factors predicting substance consumption according to Petraitis' theory of triadic influence. We assessed the predictive value of these factors with respect to binge drinking in German adolescents, including the identification of influence direction. Methods In the years 2007/2008, a representative written survey of N = 44,610 students in the 9th grade of different school types in Germany was carried out (net sample. The return rate of questionnaires was 88% regarding all students whose teachers or school directors had agreed to participate in the study. In this survey, prevalence of binge drinking was investigated as well as potential predictors from the social/interpersonal, the attitudinal/environmental, and the intrapersonal fields (3 factors of Petraitis. In a multivariate logistic regression analysis, these variables were included after testing for multicollinearity in order to assess their ability to predict binge drinking. Results Prevalence of binge drinking in the last 30 days was 52.3% for the surveyed adolescents with a higher prevalence for boys (56.9% than for girls (47.5%. The two most influential factors found to protect against binge drinking with p p Conclusions Whereas some of the risk and protective factors for binge drinking are not surprising since they are known for substance abuse in general, there are two points that

  7. 'Let's get wasted': A discourse analysis of teenagers' talk about binge drinking.

    Science.gov (United States)

    Chainey, Timothy A; Stephens, Christine

    2016-05-01

    Teenage binge drinking is a significant health issue. To explore teenagers talk about binge drinking, four peer-group interviews were conducted with 20 teenagers, aged 16-18 years, with experience of excessive alcohol use. A discourse analysis showed that a 'drinking is cool' discourse constructed 'getting wasted' as an integral part of social life, while a 'drinking as a social lubricant' discourse described the behavioural functions of alcohol use. Participants also actively resisted an 'alcohol is bad' discourse, which acknowledges the risks of alcohol use. The findings illustrate how teenagers use these resources in sophisticated ways to position the teen drinker positively and negatively.

  8. The Round Table 03 圆桌: A Conversation with Xu Bing

    Directory of Open Access Journals (Sweden)

    Madeline Eschenburg

    2015-08-01

    Full Text Available The following is an excerpt from a conversation between contemporary Chinese artist Xu Bing, Madeline Eschenburg, and Ellen Larson. Xu Bing curated an exhibition at the Central Academy of Fine Arts titled The Second CAFAM Future Exhibition, Observer-Creator: The Reality Representation of Chinese Young Art, on exhibition through March 2015. Our conversation centered around his thoughts on a new generation of young Chinese artists as well as reflection on his own early career and time in New York. The conversation was conducted in Chinese and has been translated into English.

  9. Effects of resistance training on binge eating, body composition and blood variables in type II diabetics

    OpenAIRE

    Moisés Simão Santa Rosa de Sousa; Victor Manuel Machado dos Reis; Jefferson da Silva Novaes; Josenaldo Mendes de Sousa; Divaldo Martins de Souza

    2014-01-01

    http://dx.doi.org/10.4025/actascihealthsci.v36n1.18048 This study examined the effects of 12 weeks of resistance training (RT) on binge eating, body composition and blood variables and their correlations in 34 sedentary adults with type II diabetes. The participants aged 58.94 ± 10.66, had body weight of 71.62 ± 11.85 and BMI of 29.64 ± 4.27. Blood samples were collected for analysis of serum leptin, glucose, insulin, LDL, HDL, total cholesterol and triglyceride. The binge eating was asses...

  10. Effectiveness of cognitive-behavioral therapy in morbidity obese candidates for bariatric surgery with and without binge eating disorder

    Directory of Open Access Journals (Sweden)

    V. Abilés

    2013-10-01

    Full Text Available Aims: To analyze changes in the general and specific psychopathology of morbidly obese bariatric surgery (BS candidates after cognitive behavioral therapy (CBT and assess differences between patients with and without binge eating disorder (BED and between patients with obesity grades III and IV, studying their influence on weight loss. Methods: 110 consecutive morbidly obese BS candidates [77 females; aged 41 ± 9 yrs; body mass index 49.1 ± 9.0 kg/m²] entered a three-month CBT program (12 two-hour sessions before BS. Participants were assessed with general and specific psychopathology tests pre-and post-CBT. Data were analyzed according to the degree of obesity and presence/absence of BED. Results: At baseline, BED patients were more anxious and depressive with lower self-esteem and quality of life versus non-BED patients (p 10% in 61%, with no intergroup differences. Conclusions: CBT is effective to treat psychological comorbidity in BS candidates, regardless of the presence of BED and degree of obesity.

  11. CERN restaurants: opening hours during summer

    CERN Multimedia

    2016-01-01

    In the summer, the three CERN restaurants remain open during their usual hours. On Monday 1st August and Thursday 8 September, the Restaurant 1 will be open from 7:00 a.m. to 10:00 p.m.   The satellites will be open as follows: Building 6: normal hours Building 13: normal hours Building 30: normal hours Building 40: closing at 4:30 p.m. instead of 5:00 pm Building 54: normal hours in July, closed in August Building 864: normal hours Building 865: normal hours Building 774: normal hours

  12. Long Work Hours May Hurt Your Health

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_159479.html Long Work Hours May Hurt Your Health At the job ... at Ohio State University. The link between long work hours and disease ''seems to be present a ...

  13. How Hours of Work Affect Occupational Earnings.

    Science.gov (United States)

    Hecker, David

    1998-01-01

    In most managerial, management-related, sales, production, and transportation occupations, workers with longer hours earned a high hourly rate. The reverse was true for some jobs, including computer specialists, engineers, schoolteachers, and construction workers. (JOW)

  14. The Student Credit Hour: Counting What Counts

    Science.gov (United States)

    Wellman, Jane

    2005-01-01

    The article discusses the student credit hour (SCH). The author begins with a rethinking of the basic unit of measurement in American higher education--the SCH. The credit hour was developed at the turn of the 20th century as a measure of student time in the classroom: one hour per week in class for one semester equalled one SCH. The credit hour…

  15. Effects of memantine alone and with acute 'binge' cocaine on hypothalamic-pituitary-adrenal activity in the rat.

    Science.gov (United States)

    Zhou, Y; Yuferov, V P; Spangler, R; Maggos, C E; Ho, A; Kreek, M J

    1998-07-01

    The effects of memantine, a non-competitive NMDA-receptor antagonist used in the management of dementia, and its coadministration with acute 'binge' pattern cocaine on hypothalamic-pituitary-adrenal axis activity were investigated in the rat. Measurements 3 h after injections showed that memantine alone at 20 mg kg(-1) (i.p.), but not 10 mg kg(-1), increased corticotropin-releasing factor (CRF) mRNA levels in the hypothalamus and both adrenocorticotropic hormone and corticosterone levels in the blood, and decreased type I CRF receptor mRNA in the anterior pituitary. Our previous studies have shown that acute 'binge' cocaine increases CRF mRNA levels in the hypothalamus. In this study, pretreatment with memantine (10 and 20 mg kg(-1), i.p.) did not alter the up-regulation of hypothalamic CRF mRNA induced by acute 'binge' cocaine (3 x 15 mg kg(-1), i.p.). Of interest, pretreatment with memantine at 10 mg kg(-1), which alone had no effect on corticosterone levels, caused a greater elevation of corticosterone levels in combination with 'binge' cocaine than acute 'binge' cocaine alone, indicating that memantine does not attenuate 'binge' cocaine-stimulated hypothalamic-pituitary-adrenal activity. These results indicate that both memantine and acute 'binge' cocaine stimulate hypothalamic-pituitary-adrenal activity by activating CRF neurons in the hypothalamus. PMID:9718269

  16. 12-Month Follow-Up of Fluoxetine and Cognitive Behavioral Therapy for Binge Eating Disorder

    Science.gov (United States)

    Grilo, Carlos M.; Crosby, Ross D.; Wilson, G. Terence; Masheb, Robin M.

    2012-01-01

    Objective: The longer term efficacy of medication treatments for binge-eating disorder (BED) remains unknown. This study examined the longer term effects of fluoxetine and cognitive behavioral therapy (CBT) either with fluoxetine (CBT + fluoxetine) or with placebo (CBT + placebo) for BED through 12-month follow-up after completing treatments.…

  17. Salivary cortisol and binge eating disorder in obese women after surgery for morbid obesity

    NARCIS (Netherlands)

    Larsen, J.K.; Ramshorst, B. van; Doornen, L.J.P. van; Geenen, R.

    2009-01-01

    Background Binge eating episodes characterized by loss of control are hypothesized to be accompanied by changes in hypothalamic pituitary adrenal (HPA) axis functioning. Cortisol is an end product of this neuroendocrine stress system. Purpose The aim of this study was to examine the cortisol leve

  18. POSTTRAUMATIC STRESS DISORDER IN WOMEN WITH BINGE EATING DISORDER IN PRIMARY CARE

    Science.gov (United States)

    Grilo, Carlos M.; White, Marney A.; Barnes, Rachel D.; Masheb, Robin M.

    2012-01-01

    Background To examine the frequency and significance of comorbid posttraumatic stress disorder (PTSD) in ethnically diverse obese patients with binge eating disorder (BED) seeking treatment for obesity and binge eating in primary care. Methods Participants were a consecutive series of 105 obese women with BED; 43% were African-American, 36% were Caucasian, and 21% were Hispanic-American/other. Participants were evaluated with reliable semi-structured interviews and established measures. Results Of the 105 women, 25 (24%) met criteria for PTSD. PTSD was associated with significantly elevated rates of mood, anxiety, and drug use disorders, significantly elevated eating disorder psychopathology (Eating Disorder Examination global score and scales), greater depressive affect, and lower self-esteem, even though the patients with comorbid PTSD did not have higher body mass indexes (BMIs) or greater frequency of binge eating. The heightened eating disorder psychopathology and depression and the lower self-esteem among patients with comorbid PTSD persisted even after controlling for anxiety disorder comorbidity. Conclusions Our findings suggest that among ethnically/racially diverse obese women with BED who present for obesity and binge eating treatment in primary care settings, PTSD is common and is associated with heightened psychiatric comorbidity, greater eating disorder psychopathology, and poorer psychological functioning. PMID:23160245

  19. Overeating and Binge Eating in Emerging Adulthood: 10-Year Stability and Risk Factors

    Science.gov (United States)

    Goldschmidt, Andrea B.; Wall, Melanie M.; Zhang, Jun; Loth, Katie A.; Neumark-Sztainer, Dianne

    2016-01-01

    Overeating (eating an unusually large amount of food) and binge eating (overeating with loss of control [LOC]) predict adverse health consequences in adolescence. We aimed to characterize the stability of and risk factors for these distinct but interrelated constructs during critical developmental transitions. We used a population-based sample (n…

  20. Ringkøbing-Skjern energy atlas for analysis of heat saving potentials in building stock

    DEFF Research Database (Denmark)

    Petrovic, Stefan; Karlsson, Kenneth Bernard

    2016-01-01

    Ringkøbing-Skjern municipality aims to be 100% self-sufficient in renewable energy supply starting from 2020. It is expected that the building sector will contribute by reducing energy demand by 25-50%.Technical, economic, environmental and geographical aspects need to be considered when analysing...

  1. Predicting Binge Drinking in College Students: Rational Beliefs, Stress, or Loneliness?

    Science.gov (United States)

    Chen, Yixin; Feeley, Thomas Hugh

    2015-01-01

    We proposed a conceptual model to predict binge-drinking behavior among college students, based on the theory of planned behavior and the stress-coping hypothesis. A two-wave online survey was conducted with predictors and drinking behavior measured separately over 2 weeks' time. In the Wave 1 survey, 279 students at a public university in the…

  2. Stress and binge drinking: A toxic combination for the teenage brain.

    Science.gov (United States)

    Goldstein, Aaron; Déry, Nicolas; Pilgrim, Malcolm; Ioan, Miruna; Becker, Suzanna

    2016-09-01

    Young adult university students frequently binge on alcohol and have high stress levels. Based on findings in rodents, we predicted that heavy current alcohol use and elevated stress and depression scores would be associated with deficits on high interference memory tasks, while early onset, prolonged binge patterns would lead to broader cognitive deficits on tests of associative encoding and executive functions. We developed the Concentration Memory Task, a novel computerized version of the Concentration card game with a high degree of interference. We found that young adults with elevated stress, depression, and alcohol consumption scores were impaired in the Concentration Memory Task. We also analyzed data from a previous study, and found that higher alcohol consumption scores were associated with impaired performance on another high interference memory task, based on Kirwan and Stark's Mnemonic Similarity Test. On the other hand, adolescent onset of binge drinking predicted poorer performance on broader range of memory tests, including a more systematic test of spatial recognition memory, and an associative learning task. Our results are broadly consistent with findings in rodents that acute alcohol and stress exposure suppress neurogenesis in the adult hippocampus, which in turn impairs performance in high interference memory tasks, while adolescent onset binge drinking causes more extensive brain damage and cognitive deficits. PMID:27498180

  3. A Discrepancy of Definitions: Binge Drinking and Female Students at an Australian University

    Science.gov (United States)

    Murugiah, Sera

    2012-01-01

    Women are more vulnerable to the effects of alcohol than men. They get intoxicated more quickly and have a higher blood alcohol level than men, even when body weight and alcohol consumption are the same. Despite this we are seeing a convergence of the drinking patterns of young women and young men, including binge drinking. In this research, 20…

  4. Experiential Learning in Marketing Communications Courses: The Demarketing of College Binge-Drinking

    Science.gov (United States)

    Rozensher, Susan G.; Seal, David S.

    2009-01-01

    The experiential learning approach has been gathering substantial momentum and support in educational circles. In the team-based experiential learning project presented here, which effectively integrated theory and application, students were charged with creating an integrated marketing communications plan to demarket binge drinking on the college…

  5. Faulty perceptions? The impact of binge drinking history on college women's perceived rape resistance efficacy.

    Science.gov (United States)

    McCauley, Jenna L; Calhoun, Karen S

    2008-12-01

    College women who binge drink are at greater risk than their peers for experiencing an alcohol-involved rape. Evidence suggests that these women commonly underestimate their risk for assault. This study examines college women's perceptions of their rape resistance efficacy in two acquaintance rape scenarios (one involving the woman's alcohol consumption and one not) as a function of their binge drinking and alcohol-involved rape history. Alcohol-involved rape was inversely associated only with efficacy in situations involving alcohol. Binge drinking was differentially predictive of efficacy in the two scenarios, with regular binge drinkers being significantly more likely to have high perceived efficacy in rape scenarios in which they were drinking and significantly less likely than their peers to have high perceived efficacy in rape scenarios in which they weren't drinking. Findings have direct implications for both college drinking and rape risk reduction interventions, highlighting the need to address women's minimization of alcohol's impact on their rape resistance ability. PMID:18760879

  6. Reduced cerebellar brain activity during reward processing in adolescent binge drinkers

    Directory of Open Access Journals (Sweden)

    Anita Cservenka

    2015-12-01

    Full Text Available Due to ongoing development, adolescence may be a period of heightened vulnerability to the neurotoxic effects of alcohol. Binge drinking may alter reward-driven behavior and neurocircuitry, thereby increasing risk for escalating alcohol use. Therefore, we compared reward processing in adolescents with and without a history of recent binge drinking. At their baseline study visit, all participants (age = 14.86 ± 0.88 were free of heavy alcohol use and completed a modified version of the Wheel of Fortune (WOF functional magnetic resonance imaging task. Following this visit, 17 youth reported binge drinking on ≥3 occasions within a 90 day period and were matched to 17 youth who remained alcohol and substance-naïve. All participants repeated the WOF task during a second visit (age = 16.83 ± 1.22. No significant effects were found in a region of interest analysis of the ventral striatum, but whole-brain analyses showed significant group differences in reward response at the second study visit in the left cerebellum, controlling for baseline visit brain activity (p/α < 0.05, which was negatively correlated with mean number of drinks consumed/drinking day in the last 90 days. These findings suggest that binge drinking during adolescence may alter brain activity during reward processing in a dose-dependent manner.

  7. Effects of a 10-Minutes Peer Education Protocol to Reduce Binge Drinking among Adolescents during Holidays

    Science.gov (United States)

    Planken, Martijn J. E.; Boer, Henk

    2010-01-01

    Aim of this study was to evaluate a standard ten-minute peer education protocol to reduce binge drinking among Dutch adolescents at campsites during summer holidays. Using a quasi-experimental design, we evaluated the effects of the peer education protocol as applied by trained peer educators. We collected data by telephone interviews fourteen…

  8. Health services use in women with a history of bulimia nervosa or binge eating disorder

    NARCIS (Netherlands)

    Striegel-Moore, RH; Dohm, FA; Kraemer, HC; Schreiber, GB; Crawford, PB; Daniels, [No Value

    2005-01-01

    Objective: The current study examined health services use during the past 12 months in a sample of young women with a history of an adolescent eating disorder (bulimia nervosa [BN] or binge eating disorder [BED]). Method: A community sample of 1,582 young women (mean age = 21.5 years) was classified

  9. Incidence and Weight Trajectories of Binge Eating Disorder among Young Women in the Community

    NARCIS (Netherlands)

    Mustelin, Linda; Raevuori, Anu; Hoek, Hans Wijbrand; Kaprio, Jaakko; Keski-Rahkonen, Anna

    2015-01-01

    Objective: To assess the population prevalence and incidence of binge eating disorder (BED) among young women. Method: In a nationwide longitudinal study of Finnish twins born 1975-1979, the women participated in five surveys from age 16 until their mid-thirties. At Wave 4 (mean age 24 years), the w

  10. Binge eating disorder and night eating syndrome in adults with type 2 diabetes

    Science.gov (United States)

    To determine the prevalence of binge eating disorder (BED) and night eating syndrome (NES) among applicants to the Look AHEAD (Action for Health in Diabetes) study. The Eating Disorders Examination-Questionnaire (EDE-Q) and the Night Eating Questionnaire (NEQ) were used to screen patients. Phone int...

  11. Dialectical Behavior Therapy Modified for Adolescent Binge Eating Disorder: A Case Report

    Science.gov (United States)

    Safer, Debra L.; Couturier, Jennifer L.; Lock, James

    2007-01-01

    Given the lack of empirically supported treatments available for adolescents with eating disorders, it is important to investigate the clinical utility of extending treatments for adults with eating disorders to younger populations. Dialectical behavior therapy for binge eating disorder, based on the affect-regulation model, conceptualizes binge…

  12. Racial/Ethnic Differences in Adults in Randomized Clinical Trials of Binge Eating Disorder

    Science.gov (United States)

    Franko, Debra L.; Thompson-Brenner, Heather; Thompson, Douglas R.; Boisseau, Christina L.; Davis, Angela; Forbush, Kelsie T.; Roehrig, James P.; Bryson, Susan W.; Bulik, Cynthia M.; Crow, Scott J.; Devlin, Michael J.; Gorin, Amy A.; Grilo, Carlos M.; Kristeller, Jean L.; Masheb, Robin M.; Mitchell, James E.; Peterson, Carol B.; Safer, Debra L.; Striegel, Ruth H.; Wilfley, Denise E.; Wilson, G. Terence

    2012-01-01

    Objective: Recent studies suggest that binge eating disorder (BED) is as prevalent among African American and Hispanic Americans as among Caucasian Americans; however, data regarding the characteristics of treatment-seeking individuals from racial and ethnic minority groups are scarce. The purpose of this study was to investigate racial/ethnic…

  13. Xu Bing, Ed Pien and Gu Xiong: Lost and Found in Translation

    Science.gov (United States)

    Mahon, Patrick

    2008-01-01

    The works of contemporary artists Xu Bing, Ed Pien and Gu Xiong are involved in bringing to light some of the factors inherent in social, cultural and linguistic translation. In doing so, each artist is also engaged in the nuanced activity of moving between historical and contemporary aesthetic strategies in order to interrogate the way meaning is…

  14. Binge Eating Disorder and Night Eating Syndrome: A Comparative Study of Disordered Eating

    Science.gov (United States)

    Allison, Kelly C.; Grilo, Carlos M.; Masheb, Robin M.; Stunkard, Albert J.

    2005-01-01

    The authors compared eating patterns, disordered eating, features of eating disorders, and depressive symptoms in persons with binge eating disorder (BED; n = 177), with night eating syndrome (NES; n = 68), and in an overweight comparison group without BED or NES (comparison; n = 45). Participants completed semistructured interviews and several…

  15. The Clinical Features of Binge Eating Disorder and Bulimia Nervosa: What Are the Differences?

    Science.gov (United States)

    Sullivan, Keri A.

    2001-01-01

    Compares the clinical characteristics of binge eating disorder (BED) and the related syndrome bulimia nervosa (BN). Findings suggest individuals with BED are distinguishable from those with BN on a number of traits, including higher rates of obesity and lower levels of eating concern and dietary restraint. (Contains 29 references and 2 tables.)…

  16. The relationship between age at drinking onset and subsequent binge drinking among women

    DEFF Research Database (Denmark)

    Eliasen, Marie; Kaer, Susanne K; Munk, Christian;

    2009-01-01

    in Denmark, Iceland, Norway and Sweden. Frequency of binge drinking, defined as consuming >6 U of alcohol at the same occasion once or more per month, and age at drinking debut were assessed through a questionnaire survey. RESULTS: Overall, 12-26% reported binge drinking once or more per month in the four...... countries. Median age for starting drinking was 16 years in all four countries. Women who started drinking at 14 years or younger were significantly more likely to binge drink than women who started drinking at 19 years or older with adjusted odds ratios of 2.9 (95% confidence intervals 2.3-3.7), 2.8 (2.......1-3.6) and 2.6 (1.9-3.4) for binge drinking in Denmark, Iceland and Sweden, respectively. Among Norwegian women the association was stronger with an adjusted odds ratio at 4.4 (3.5-5.6). The association in all four countries was more pronounced in women younger than 30 years than in older women. CONCLUSION...

  17. Does impulsivity predict outcome in treatment for binge eating disorder? A multimodal investigation.

    Science.gov (United States)

    Manasse, Stephanie M; Espel, Hallie M; Schumacher, Leah M; Kerrigan, Stephanie G; Zhang, Fengqing; Forman, Evan M; Juarascio, Adrienne S

    2016-10-01

    Multiple dimensions of impulsivity (e.g., affect-driven impulsivity, impulsive inhibition - both general and food-specific, and impulsive decision-making) are associated with binge eating pathology cross-sectionally, yet the literature on whether impulsivity predicts treatment outcome is limited. The present pilot study explored impulsivity-related predictors of 20-week outcome in a small open trial (n = 17) of a novel treatment for binge eating disorder. Overall, dimensions of impulsivity related to emotions (i.e., negative urgency) and food cues emerged as predictors of treatment outcomes (i.e., binge eating frequency and global eating pathology as measured by the Eating Disorders Examination), while more general measures of impulsivity were statistically unrelated to global eating pathology or binge frequency. Specifically, those with higher levels of negative urgency at baseline experienced slower and less pronounced benefit from treatment, and those with higher food-specific impulsivity had more severe global eating pathology at baseline that was consistent at post-treatment and follow-up. These preliminary findings suggest that patients high in negative urgency and with poor response inhibition to food cues may benefit from augmentation of existing treatments to achieve optimal outcomes. Future research will benefit from replication with a larger sample, parsing out the role of different dimensions of impulsivity in treatment outcome for eating disorders, and identifying how treatment can be improved to accommodate higher levels of baseline impulsivity. PMID:27230611

  18. Combining Pharmacological and Psychological Treatments for Binge Eating Disorder: Current Status, Limitations, and Future Directions.

    Science.gov (United States)

    Grilo, Carlos M; Reas, Deborah L; Mitchell, James E

    2016-06-01

    Binge eating disorder (BED) is characterized by recurrent binge eating and marked distress about binge eating without the extreme compensatory behaviors for weight control that characterize other eating disorders. BED is prevalent, associated strongly with obesity, and is associated with heightened levels of psychological, psychiatric, and medical concerns. This article provides an overview of randomized controlled treatments for combined psychological and pharmacological treatment of BED to inform current clinical practice and future treatment research. In contrast to the prevalence and significance of BED, to date, limited research has been performed on combining psychological and pharmacological treatments for BED to enhance outcomes. Our review here found that combining certain medications with cognitive behavioral therapy (CBT) or behavioral weight loss (BWL) interventions produces superior outcomes to pharmacotherapy only but does not substantially improve outcomes achieved with CBT/BWL only. One medication (orlistat) has improved weight losses with CBT/BWL albeit minimally, and only one medication (topiramate) has enhanced reductions achieved with CBT in both binge eating and weight. Implications for future research are discussed. PMID:27086316

  19. Dialectical Behavior Therapy Modified for Adolescent Binge Eating Disordspan>er: A Case Report

    Science.gov (United States)

    Safer, Debra L.; Couturier, Jennifer L.; Lock, James

    2007-01-01

    Given the lack of empirically supported treatments available for adolescents with eating disorders, it is important to investigate the clinical utility of extending treatments for adults with eating disorders to younger populations. Dialectical behavior therapy for binge eating disorder, based on the affect-regulation model, conceptualizes binge…

  20. Binge Eating Disordspan>er: A Review of a New "DSM" Diagnosis

    Science.gov (United States)

    Myers, Laura L.; Wiman, Allison M.

    2014-01-01

    In 1994, binge eating disorder (BED) was introduced as a disorder requiring further study in the "American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders", fourth edition ("DSM-IV"). It is now listed as a distinct eating disorder in the "DSM-5", along with bulimia nervosa and…

  1. Heterogeneity Moderates Treatment Response among Patients with Binge Eating Disordspan>er

    Science.gov (United States)

    Sysko, Robyn; Hildebrandt, Tom; Wilson, G. Terence; Wilfley, Denise E.; Agras, W. Stewart

    2010-01-01

    Objective: The purpose of the study was to explore heterogeneity and differential treatment outcome among a sample of patients with binge eating disorder (BED). Method: A latent class analysis was conducted with 205 treatment-seeking, overweight or obese individuals with BED randomized to interpersonal psychotherapy (IPT), behavioral weight loss…

  2. Racial/Ethnic Differences in Adults in Randomized Clinical Trials of Binge Eating Disordspan>er

    Science.gov (United States)

    Franko, Debra L.; Thompson-Brenner, Heather; Thompson, Douglas R.; Boisseau, Christina L.; Davis, Angela; Forbush, Kelsie T.; Roehrig, James P.; Bryson, Susan W.; Bulik, Cynthia M.; Crow, Scott J.; Devlin, Michael J.; Gorin, Amy A.; Grilo, Carlos M.; Kristeller, Jean L.; Masheb, Robin M.; Mitchell, James E.; Peterson, Carol B.; Safer, Debra L.; Striegel, Ruth H.; Wilfley, Denise E.; Wilson, G. Terence

    2012-01-01

    Objective: Recent studies suggest that binge eating disorder (BED) is as prevalent among African American and Hispanic Americans as among Caucasian Americans; however, data regarding the characteristics of treatment-seeking individuals from racial and ethnic minority groups are scarce. The purpose of this study was to investigate racial/ethnic…

  3. Stress and binge drinking: A toxic combination for the teenage brain.

    Science.gov (United States)

    Goldstein, Aaron; Déry, Nicolas; Pilgrim, Malcolm; Ioan, Miruna; Becker, Suzanna

    2016-09-01

    Young adult university students frequently binge on alcohol and have high stress levels. Based on findings in rodents, we predicted that heavy current alcohol use and elevated stress and depression scores would be associated with deficits on high interference memory tasks, while early onset, prolonged binge patterns would lead to broader cognitive deficits on tests of associative encoding and executive functions. We developed the Concentration Memory Task, a novel computerized version of the Concentration card game with a high degree of interference. We found that young adults with elevated stress, depression, and alcohol consumption scores were impaired in the Concentration Memory Task. We also analyzed data from a previous study, and found that higher alcohol consumption scores were associated with impaired performance on another high interference memory task, based on Kirwan and Stark's Mnemonic Similarity Test. On the other hand, adolescent onset of binge drinking predicted poorer performance on broader range of memory tests, including a more systematic test of spatial recognition memory, and an associative learning task. Our results are broadly consistent with findings in rodents that acute alcohol and stress exposure suppress neurogenesis in the adult hippocampus, which in turn impairs performance in high interference memory tasks, while adolescent onset binge drinking causes more extensive brain damage and cognitive deficits.

  4. Predicting Premature Termination within a Randomized Controlled Trial for Binge-Eating Patients

    Science.gov (United States)

    Fluckiger, Christoph; Meyer, Andrea; Wampold, Bruce E.; Gassmann, Daniel; Messerli-Burgy, Nadine; Munsch, Simone

    2011-01-01

    Understanding the dropout rates of efficacious forms of psychotherapy for patients with binge eating disorder (BED) is an unsolved problem within this increasing population. Up until now the role of psychotherapy process characteristics as predictors of premature termination has not been investigated in the BED literature. Within a randomized…

  5. Associations between Responsible Beverage Service Laws and Binge Drinking and Alcohol-Impaired Driving

    Science.gov (United States)

    Linde, Ann C.; Toomey, Traci L.; Wolfson, Julian; Lenk, Kathleen M.; Jones-Webb, Rhonda; Erickson, Darin J.

    2016-01-01

    We explored potential associations between the strength of state Responsible Beverage Service (RBS) laws and self-reported binge drinking and alcohol-impaired driving in the U.S. A multi-level logistic mixed-effects model was used, adjusting for potential confounders. Analyses were conducted on the overall BRFSS sample and drinkers only. Seven…

  6. Personality-Targeted Interventions Delay the Growth of Adolescent Drinking and Binge Drinking

    Science.gov (United States)

    Conrod, Patricia J.; Castellanos, Natalie; Mackie, Clare

    2008-01-01

    Background: Personality factors are implicated in the vulnerability to adolescent alcohol misuse. This study examined whether providing personality-targeted interventions in early adolescence can delay drinking and binge drinking in high-risk youth. Methods: A randomised control trial was carried out with 368 adolescents recruited from years 9 and…

  7. Impulsivity-focused group intervention to reduce binge eating episodes in patients with binge eating disorder: study protocol of the randomised controlled IMPULS trial

    Science.gov (United States)

    Schag, Kathrin; Leehr, Elisabeth J; Martus, Peter; Bethge, Wolfgang; Becker, Sandra; Zipfel, Stephan; Giel, Katrin E

    2015-01-01

    Introduction The core symptom of binge eating disorder (BED) is recurrent binge eating that is accompanied by a sense of loss of control. BED is frequently associated with obesity, one of the main public health challenges today. Experimental studies deliver evidence that general trait impulsivity and disorder-specific food-related impulsivity constitute risk factors for BED. Cognitive-behavioural treatment (CBT) is deemed to be the most effective intervention concerning BED. We developed a group intervention based on CBT and especially focusing on impulsivity. We hypothesise that such an impulsivity-focused group intervention is able to increase control over impulsive eating behaviour, that is, reduce binge eating episodes, further eating pathology and impulsivity. Body weight might also be influenced in the long term. Methods and analysis The present randomised controlled trial investigates the feasibility, acceptance and efficacy of this impulsivity-focused group intervention in patients with BED. We compare 39 patients with BED in the experimental group to 39 patients with BED in the control group at three appointments: before and after the group intervention and in a 3-month follow-up. Patients with BED in the experimental group receive 8 weekly sessions of the impulsivity-focused group intervention with 5-6 patients per group. Patients with BED in the control group receive no group intervention. The primary outcome is the binge eating frequency over the past 4 weeks. Secondary outcomes comprise further eating pathology, general impulsivity and food-related impulsivity assessed by eye tracking methodology, and body weight. Additionally, we assess binge eating and other impulsive behaviour weekly in process analyses during the time period of the group intervention. Ethics and dissemination This study has been approved by the ethics committee of the medical faculty of Eberhard Karls University Tübingen and the University Hospital Tübingen. Data are monitored

  8. Employment, hours and optimal monetary policy

    OpenAIRE

    2014-01-01

    We characterize optimal monetary policy in a New Keynesian search-and-matching model where multiple-worker firms satisfy demand in the short run by adjusting hours per worker. Imperfect product market competition and search frictions reduce steady state hours per worker below the efficient level. Bargaining results in a convex ‘wage curve’ linking wages to hours. Since the steady-state real marginal wage is low, wages respond little to hours. As a result, firms overuse the hours margin at the...

  9. Alcohol binge drinking during adolescence or dependence during adulthood reduces prefrontal myelin in male rats.

    Science.gov (United States)

    Vargas, Wanette M; Bengston, Lynn; Gilpin, Nicholas W; Whitcomb, Brian W; Richardson, Heather N

    2014-10-29

    Teen binge drinking is associated with low frontal white matter integrity and increased risk of alcoholism in adulthood. This neuropathology may result from alcohol exposure or reflect a pre-existing condition in people prone to addiction. Here we used rodent models with documented clinical relevance to adolescent binge drinking and alcoholism in humans to test whether alcohol damages myelinated axons of the prefrontal cortex. In Experiment 1, outbred male Wistar rats self-administered sweetened alcohol or sweetened water intermittently for 2 weeks during early adolescence. In adulthood, drinking behavior was tested under nondependent conditions or after dependence induced by 1 month of alcohol vapor intoxication/withdrawal cycles, and prefrontal myelin was examined 1 month into abstinence. Adolescent binge drinking or adult dependence induction reduced the size of the anterior branches of the corpus callosum, i.e., forceps minor (CCFM), and this neuropathology correlated with higher relapse-like drinking in adulthood. Degraded myelin basic protein in the gray matter medial to the CCFM of binge rats indicated myelin was damaged on axons in the mPFC. In follow-up studies we found that binge drinking reduced myelin density in the mPFC in adolescent rats (Experiment 2) and heavier drinking predicted worse performance on the T-maze working memory task in adulthood (Experiment 3). These findings establish a causal role of voluntary alcohol on myelin and give insight into specific prefrontal axons that are both sensitive to alcohol and could contribute to the behavioral and cognitive impairments associated with early onset drinking and alcoholism.

  10. Appetite-related hormone levels in obese women with and without binge eating behavior

    Directory of Open Access Journals (Sweden)

    Paula Paraguassú Brandão

    2011-10-01

    Full Text Available OBJECTIVE: The aim of this study was to evaluate serum levels of appetite-related hormones (peptide YY3-36, total ghrelin, leptin and insulin before and after consumption of a meal in obese women with and without binge eating episodes and normal weight women. METHODS: Twenty-five women aged 32-50 years were invited to participate in this study, including 9 normal weight women without binge eating episodes (20-25kg/m², group 1, 9 obese women with binge eating episodes (³30kg/m², group 2, and 7 obese women without binge eating episodes (group 3. Four blood samples were collected from each participant, one being 60 minutes before and three being 15, 45 and 90 minutes after a meal. The composition of the meal was 55% carbohydrates, 15% protein and 30% lipids. RESULTS: Group 3 presented increased HOMA-IR (M=2.5, SD=1.04 when compared with group 1 (M=1.5, SD=0.53 and group 2 (M=1.8, SD=0.58, p=0.04. Body mass index (p<0.0001, leptin (p<0.0001 and insulin (p=0.01 were higher in group 3 than in the other groups before and after the meal. Additionally, total ghrelin (p=0.003 and PYY3-36 (p=0.02 levels were lower in group 2 than in the other groups before and after the meal. After adjustment for body mass index, only the lower PYY3-36 level of group 2 remained statistically different from the other groups (p=0.01. CONCLUSION: Our study suggests that lower levels of PYY 3-36 are associated with binge eating in obese women.

  11. Evaluation of the DSM-5 Severity Indicator for Binge Eating Disorder in a Community Sample

    Science.gov (United States)

    Grilo, Carlos M.; Ivezaj, Valentina; White, Marney A.

    2015-01-01

    Research has examined various aspects of the diagnostic criteria for binge-eating disorder (BED) but has yet to evaluate the DSM-5 severity criterion. This study examined the DSM-5 severity criterion for BED based on binge-eating frequency and tested an alternative severity specifier based on overvaluation of shape/weight. 338 community volunteers categorized with DSM-5 BED completed a battery of self-report instruments. Participants were categorized first using DSM-5 severity levels and second by shape/weight overvaluation and were compared on clinical variables. 264 (78.1%) participants were categorized as mild, 67 (19.8%) as moderate, 6 (1.8%) as severe, and 1 (0.3%) as extreme. Analyses comparing mild and moderate severity groups revealed no significant differences in demographic variables or BMI; moderate severity group had greater eating-disorder psychopathology (small effect-sizes) but not depression than mild group. Participants with overvaluation (N=196; 60.1%) versus without (N=130; 39.9%) did not differ significantly in age, sex, BMI, or binge-eating frequency. Overvaluation group had significantly greater eating-disorder psychopathology and depression than non-overvaluation group. The greater eating-disorder and depression levels (medium-to-large effect-sizes) persisted after adjusting for ethnicity/race and binge-eating severity/frequency, without attenuation of effect-sizes. Findings from this non-clinical community sample provide support for overvaluation of shape/weight as a specifier for BED as it provides stronger information about severity than the DSM-5 rating based on binge-eating. Future research should include treatment-seeking patients with BED to test the utility of DSM-5 severity specifiers and include broader clinical validators. PMID:25701802

  12. The Psychological and Medical Factors Associated With Untreated Binge Eating Disorder

    Science.gov (United States)

    Herman, Barry K.

    2015-01-01

    Objective: Although binge eating disorder (BED) is the most prevalent eating disorder, the impact of untreated BED is underappreciated. This review describes the relationship of BED to physical and mental health, quality of life, and functionality. Data Sources: PubMed searches were conducted on March 21, 2014; searches were limited to English-language research articles, meta-analyses, and reviews published between January 1, 2003 and March 21, 2014. Search terms included (binge eating OR binge-eating OR binge eating disorder) AND (cardiovascular OR metabolic OR metabolic syndrome OR gastrointestinal OR health OR rehabilitation OR recovery OR sleep OR pregnancy OR quality of life OR functional impairment OR activities of daily living OR QoL OR SF-12 OR ED-5D OR SF-36 OR psychosocial OR depressive OR anxiety OR self-esteem OR suicidality OR suicide OR productivity OR family). Study Selection/Data Extraction: Of 326 identified publications, 43 were relevant to the topic and reported on the association of BED with psychiatric and medical comorbidities, quality of life, and functional outcomes. Results: Individuals diagnosed with BED have increased rates of mental health comorbidities (eg, depression and anxiety) and more pronounced medical impairments (eg, cardiovascular disorders) compared with individuals without BED. BED is also associated with functional impairment and reduced quality of life. Conclusions: Binge eating disorder is associated with impairments in physical and mental health, which can decrease quality of life and functionality and lead to increased health care utilization and decreased productivity. However, some caution is warranted in interpreting these findings because it remains unclear whether BED is an antecedent condition, a complication associated with a comorbid psychiatric condition, or an unrelated feature that occurs concurrently with these comorbidities and impairments. Much of the research on BED is based on observational or

  13. Evaluation of the DSM-5 severity indicator for binge eating disorder in a clinical sample

    Science.gov (United States)

    Grilo, Carlos M.; Ivezaj, Valentina; White, Marney A.

    2015-01-01

    Objective This study tested the new DSM-5 severity criterion for binge eating disorder (BED) based on frequency of binge-eating in a clinical sample. This study also tested overvaluation of shape/weight as an alternative severity specifier. Method Participants were 834 treatment-seeking adults diagnosed with DSM-5 BED using semistructured diagnostic and eating-disorder interviews. Participants sub-grouped based on DSM-5 severity levels and on overvaluation of shape/weight were compared on demographic and clinical variables. Results Based on DSM-5 severity definitions, 331 (39.7%) participants were categorized as mild, 395 (47.5%) as moderate, 83 (10.0%) as severe, and 25 (3.0%) as extreme. Analyses comparing three (mild, moderate, and severe/extreme) severity groups revealed no significant differences in demographic variables or body mass index (BMI). Analyses revealed significantly higher eating-disorder psychopathology in the severe/extreme than moderate and mild groups and higher depression in moderate and severe/extreme groups than the mild group; effect sizes were small. Participants characterized with overvaluation (N = 449; 54%) versus without overvaluation (N = 384; 46%) did not differ significantly in age, sex, BMI, or binge-eating frequency, but had significantly greater eating-disorder psychopathology and depression. The robustly greater eating-disorder psychopathology and depression levels (medium-to-large effect sizes) in the overvaluation group was observed without attenuation of effect sizes after adjusting for ethnicity/race and binge-eating severity/frequency. Conclusions Our findings provide support for overvaluation of shape/weight as a severity specifier for BED as it provides stronger information about the severity of homogeneous groupings of patients than the DSM-5 rating based on binge-eating. PMID:26114779

  14. A narrative review of binge eating and addictive behaviors: Shared associations with seasonality and personality factors

    Directory of Open Access Journals (Sweden)

    Caroline eDavis

    2013-12-01

    Full Text Available Binge eating disorder (BED and seasonal affective disorder (SAD were first described as clinically-relevant conditions in very close temporal proximity a few decades ago. Both disorders have a higher prevalence rate in woman than in men, are characterized by a high proneness-to-stress and manifest heightened responsiveness to high-calorie, hyper-palatable foods. In recent years, a compelling body of evidence suggests that foods high in sugar and fat have the potential to alter brain reward circuitry in a manner similar to that seen when addictive drugs like alcohol and heroin are consumed in excess. These findings have led to suggestions that some cases of compulsive overeating may be understood as an addiction to sweet, fatty, and salty foods. In this paper, it is proposed that high seasonality is a risk factor for binge eating, especially in those characterized by anxious and impulsive personality traits – associations that could only occur in an environment with a superfluity of, and easy access to, rich and tasty foods. Given the well-established links between binge eating and addiction disorders (22-24 for reviews, it is also suggested that seasonality, together with the same high-risk psychological profile, exacerbates the likelihood of engaging in a broad range of addictive behaviors. Data from a community sample (n=412 of adults tested these models using linear regression procedures. Results confirmed that symptoms of binge eating and other addictive behaviors were significantly inter-correlated, and that seasonality, gender, and addictive personality traits were strong statistical predictors of the variance in binge-eating scores. Seasonality and addictive personality traits also accounted for a significant proportion of the variance in the measure of addictive behaviors. Conclusions are discussed in the context of brain reward mechanisms, motivational alternations in response to chronic over-consumption, and their relevance for the

  15. 7 CFR 1948.72 - Industry reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Industry reports. 1948.72 Section 1948.72 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... § 1948.72 Industry reports. Any person regularly engaged in any coal or uranium development...

  16. 41 CFR 105-72.404 - Equipment.

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    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Equipment. 105-72.404... NON-PROFIT ORGANIZATIONS 72.40-Post-Award Requirements/Property Standards § 105-72.404 Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the recipient, subject...

  17. 43 CFR 12.72 - Equipment.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Equipment. 12.72 Section 12.72 Public... to State and Local Governments Changes, Property, and Subawards § 12.72 Equipment. (a) Title. Subject to the obligations and conditions set forth in this section, title to equipment acquired under...

  18. 49 CFR 386.72 - Imminent hazard.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Imminent hazard. 386.72 Section 386.72... Injunctions and Imminent Hazards § 386.72 Imminent hazard. (a) Whenever it is determined that an imminent hazard exists as a result of the transportation by motor vehicle of a particular hazardous material,...

  19. 9 CFR 354.72 - Packaging.

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    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Packaging. 354.72 Section 354.72... CERTIFICATION VOLUNTARY INSPECTION OF RABBITS AND EDIBLE PRODUCTS THEREOF Supervision of Marking and Packaging § 354.72 Packaging. No container which bears or may bear any official identification or any...

  20. 41 CFR 105-72.503 - Competition.

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    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Competition. 105-72.503... NON-PROFIT ORGANIZATIONS 72.50-Post-Award Requirements/Procurement Standards § 105-72.503 Competition... practical, open and free competition. The recipient shall be alert to organizational conflicts of...

  1. 10 CFR 72.34 - Environmental report.

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    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Environmental report. 72.34 Section 72.34 Energy NUCLEAR..., and Contents § 72.34 Environmental report. Each application for an ISFSI or MRS license under this part must be accompanied by an Environmental Report which meets the requirements of subpart A of...

  2. 10 CFR 72.86 - Criminal penalties.

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    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Criminal penalties. 72.86 Section 72.86 Energy NUCLEAR..., Inspections, and Enforcement § 72.86 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended, provides for criminal sanctions for willful violation of, attempted violation of, or...

  3. 50 CFR 32.72 - Guam.

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    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Guam. 32.72 Section 32.72 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM HUNTING AND FISHING Refuge-Specific Regulations for Hunting and Fishing § 32.72 Guam. We have opened the following refuge...

  4. 9 CFR 72.4 - [Reserved

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    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false 72.4 Section 72.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TEXAS (SPLENETIC) FEVER IN CATTLE § 72.4...

  5. 9 CFR 72.14 - [Reserved

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    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false 72.14 Section 72.14 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TEXAS (SPLENETIC) FEVER IN CATTLE § 72.14...

  6. 15 CFR 930.72 - Person.

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    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Person. 930.72 Section 930.72 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND..., Development and Production Activities § 930.72 Person. The term “person” means any individual,...

  7. 40 CFR 72.9 - Standard requirements.

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    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Standard requirements. 72.9 Section 72...) PERMITS REGULATION Acid Rain Program General Provisions § 72.9 Standard requirements. (a) Permit... Quality Standards or State Implementation Plans. (2) Limiting the number of allowances a source can...

  8. 7 CFR 1780.72 - Procurement methods.

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    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Procurement methods. 1780.72 Section 1780.72..., Constructing and Inspections § 1780.72 Procurement methods. Procurement shall be made by one of the following methods: Small purchase procedures; competitive sealed bids (formal advertising); competitive...

  9. 30 CFR 72.610 - Abrasive blasting.

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    2010-07-01

    ... respirators approved for abrasive blasting by NIOSH under 42 CFR part 84, or the operation shall be performed... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Abrasive blasting. 72.610 Section 72.610... HEALTH STANDARDS FOR COAL MINES Miscellaneous § 72.610 Abrasive blasting. (a) Surface and...

  10. 30 CFR 7.72 - New technology.

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    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false New technology. 7.72 Section 7.72 Mineral... MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Multiple-Shot Blasting Units § 7.72 New technology. MSHA may approve a blasting unit that incorporates technology for which the requirements of...

  11. 46 CFR 72.20-15 - Construction.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Construction. 72.20-15 Section 72.20-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS CONSTRUCTION AND ARRANGEMENT Accommodations for Officers and Crew § 72.20-15 Construction. All crew spaces are to be constructed and...

  12. MIXING STUDY FOR JT-71/72 TANKS

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S.

    2013-11-26

    All modeling calculations for the mixing operations of miscible fluids contained in HBLine tanks, JT-71/72, were performed by taking a three-dimensional Computational Fluid Dynamics (CFD) approach. The CFD modeling results were benchmarked against the literature results and the previous SRNL test results to validate the model. Final performance calculations were performed by using the validated model to quantify the mixing time for the HB-Line tanks. The mixing study results for the JT-71/72 tanks show that, for the cases modeled, the mixing time required for blending of the tank contents is no more than 35 minutes, which is well below 2.5 hours of recirculation pump operation. Therefore, the results demonstrate the adequacy of 2.5 hours’ mixing time of the tank contents by one recirculation pump to get well mixed.

  13. Alcohol consumption and binge drinking in early pregnancy. A cross-sectional study with data from the Copenhagen Pregnancy Cohort

    DEFF Research Database (Denmark)

    Iversen, Mette Langeland; Sørensen, Nina Olsén; Broberg, Lotte;

    2015-01-01

    BACKGROUND: Since 2007 the Danish Health and Medicines Authority has advised total alcohol abstinence from the time of trying to conceive and throughout pregnancy. The prevalence of binge drinking among pregnant Danish women has nevertheless been reported to be up to 48 % during early pregnancy...... pregnancy. The overall proportion of women reporting binge drinking during early pregnancy was 35 % (n = 1,134). The following independent risk factors for binge drinking in early pregnancy were identified: lower degree of planned pregnancy, smoking and alcohol habits before pregnancy ((1 unit/weekly aOR 4...... considerably during early pregnancy compared with pre-pregnancy levels. Nevertheless one third of the pregnant women engaged in binge drinking. Identification of risk factors for this behaviour renders it possible not only to design prevention strategies, but also to target those most at risk....

  14. Do Orexins contribute to impulsivity-driven binge consumption of rewarding stimulus and transition to drug/food dependence?

    Science.gov (United States)

    Alcaraz-Iborra, Manuel; Cubero, Inmaculada

    2015-07-01

    Orexins (OX) are neuropeptides synthesized in the lateral hypothalamic region which play a fundamental role in a wide range of physiological and psychological functions including arousal, stress, motivation or eating behaviors. This paper reviews under the addiction cycle framework (Koob, 2010), the role of the OX system as a key modulator in compulsivity-driven consumption of rewarding stimulus including ethanol, palatable food and drugs and their role in impulsivity and binge-like consumption in non dependent organisms as well. We propose here that drug/food binge-like consumption in vulnerable organisms increases OX activity which, in turn, elicits enhanced impulsivity and further impulsivity-driven binge consumption in a positive loop that would promote compulsive-driven binge-consumption and the transition to drug/food disorders over time. PMID:25931265

  15. Socioeconomic patterning of excess alcohol consumption and binge drinking: a cross-sectional study of multilevel associations with neighbourhood deprivation

    OpenAIRE

    Fone, David L.; Farewell, Daniel M; White, James; Lyons, Ronan A.; Dunstan, Frank D.

    2013-01-01

    Objectives The influence of neighbourhood deprivation on the risk of harmful alcohol consumption, measured by the separate categories of excess consumption and binge drinking, has not been studied. The study objective was to investigate the effect of neighbourhood deprivation with age, gender and socioeconomic status (SES) on (1) excess alcohol consumption and (2) binge drinking, in a representative population survey. Design Cross-sectional study: multilevel analysis. Setting Wales, UK, adult...

  16. Binge Eating Disorder Mediates Links between Symptoms of Depression, Anxiety, and Caloric Intake in Overweight and Obese Women

    Directory of Open Access Journals (Sweden)

    Roseann E. Peterson

    2012-01-01

    . The associations between internalizing symptoms and food intake are best described as operating indirectly through a BED diagnosis. This suggests that symptoms of depression and anxiety influence whether one engages in binge eating, which influences kcal intake. Greater understanding of the mechanisms underlying the associations between mood, binge eating, and food intake will facilitate the development of more effective prevention and treatment strategies for both BED and obesity.

  17. Evaluating the indirect effect of self-compassion on binge eating severity through cognitive-affective self-regulatory pathways.

    Science.gov (United States)

    Webb, Jennifer B; Forman, Mallory J

    2013-04-01

    Current theory and evidence point to disruptions in self-concept and difficulties with emotion regulation as contributing to the severity of binge eating. Alternatively, contemporary perspectives on self-compassion suggest that individual differences in this adaptive approach to self-regulation may serve to counteract these cognitive-affective triggers presumably resulting in reductions in binge eating severity. Accordingly, the present cross-sectional analysis examined an indirect effect model of positive dimensions of self-compassion on binge eating severity through both emotional tolerance and unconditional self-acceptance pathways. Two hundred fifteen undergraduate students (78% female) completed self-report measures of the variables of interest; BMI was calculated from self-reported heights and weights. Pearson's correlations revealed a positive linear association between self-compassion and unconditional self-acceptance; negative links were observed between self-compassion and emotional intolerance along with the severity of binge eating symptoms. A subsequent multiple mediator analysis utilizing both normal test theory and robust non-parametric bootstrap resampling procedures confirmed the presence of a significant total indirect effect of self-compassion on binge eating severity (-.15, pmodel adjusted for BMI. Preliminary results underscore the need to further evaluate the tenability of this model in both prospective cohort and intervention-based research. Findings additionally invite considering the value of integrating self-compassion training into college health promotion efforts towards mitigating the appreciable levels of binge eating behavior prevalent in this at-risk population. PMID:23557826

  18. 46 CFR 15.710 - Working hours.

    Science.gov (United States)

    2010-10-01

    ..., prescribes certain rest periods, and prohibits unnecessary work on Sundays and certain holidays when the... 46 Shipping 1 2010-10-01 2010-10-01 false Working hours. 15.710 Section 15.710 Shipping COAST... Limitations and Qualifying Factors § 15.710 Working hours. In addition to prescribing watch requirements, 46...

  19. 47 CFR 0.403 - Office hours.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Office hours. 0.403 Section 0.403 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION General Information General § 0.403 Office hours. The main offices of the Commission are open from 8 a.m. to 5:30 p.m., Monday...

  20. 75 FR 9376 - Hours of Service

    Science.gov (United States)

    2010-03-02

    ... Federal Motor Carrier Safety Administration 49 CFR Part 395 RIN 2126-AB26 Hours of Service AGENCY: Federal... held in January 2010) to solicit comments and information on potential hours-of-service (HOS... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit...

  1. 24-Hour Academic Libraries: Adjusting to Change

    Science.gov (United States)

    Bowman, Adam C.

    2013-01-01

    The purpose of this study was to explore the adaptive measures that academic libraries perform when implementing and operating a 24-hour schedule. Five in-depth interviews were conducted with current managerial-level librarians at 24-hour academic libraries. The exploratory interviews revealed similar measures for security, budgeting, employee…

  2. The Student Credit Hour: An International Exploration.

    Science.gov (United States)

    Wolanin, Thomas R.

    2003-01-01

    Explored if and how the credit hour is used in higher education outside of the United States, with a focus on its use in measuring student progress and attainment. The use of the credit hour in Europe, where it has fostered innovation, and in Japan, and Australia generally follows the fundamentals of the U.S. model. (SLD)

  3. The Credit Hour and Public Budgeting.

    Science.gov (United States)

    Wellman, Jane V.

    2003-01-01

    Discusses the ways the credit hour has come to be used by public funding systems in higher education. The literature review shows that the credit hour has become a barrier to innovation and a way to create systemic inequities between institutions or sectors in resource allocation. (SLD)

  4. The Credit Hour and Faculty Instructional Workload.

    Science.gov (United States)

    Ehrlich, Thomas

    2003-01-01

    Studied the credit hour as a measure of faculty workload through interviews with administrators at several public and private colleges and universities. The credit hour metric did not appear to be stifling innovation, although at some public campuses those regulations made innovation more difficult. (SLD)

  5. 17 CFR 201.104 - Business hours.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Business hours. 201.104 Section 201.104 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES OF PRACTICE Rules of Practice General Rules § 201.104 Business hours. The Headquarters office of the Commission,...

  6. 20 CFR 801.304 - Business hours.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Business hours. 801.304 Section 801.304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR ESTABLISHMENT AND OPERATION OF THE BOARD Action by the Board § 801.304 Business hours. The office of the Clerk of the Board at Washington,...

  7. Mindfulness-based eating awareness training for treating binge eating disorder: the conceptual foundation.

    Science.gov (United States)

    Kristeller, Jean L; Wolever, Ruth Q

    2011-01-01

    This paper reviews the conceptual foundation of mindfulness-based eating awareness training (MB-EAT). It provides an overview of key therapeutic components as well as a brief review of current research. MB-EAT is a group intervention that was developed for treatment of binge eating disorder (BED) and related issues. BED is marked by emotional, behavioral and physiological disregulation in relation to food intake and self-identity. MB-EAT involves training in mindfulness meditation and guided mindfulness practices that are designed to address the core issues of BED: controlling responses to varying emotional states; making conscious food choices; developing an awareness of hunger and satiety cues; and cultivating self-acceptance. Evidence to date supports the value of MB-EAT in decreasing binge episodes, improving one's sense of self-control with regard to eating, and diminishing depressive symptoms.

  8. An Exploratory Study of a Meditation-based Intervention for Binge Eating Disorder.

    Science.gov (United States)

    Kristeller, J L; Hallett, C B

    1999-05-01

    The efficacy of a 6-week meditation-based group intervention for Binge Eating Disorder (BED) was evaluated in 18 obese women, using standard and eating-specific mindfulness meditation exercises. A single-group extended baseline design assessed all variables at 3 weeks pre-and post-, and at 1, 3, and 6 weeks; briefer assessment occurred weekly.Binges decreased in frequency, from 4.02/week to 1.57/week (p Eating Scale (BES) and on the Beck Depression and Anxiety Inventories decreased significantly; sense of control increased. Time using eatingrelated meditations predicted decreases on the BES (r 5 .66, p < .01). Results suggest that meditation training may be an effective component in treating BED.

  9. I Working with dissociative dynamics and the longing for excess in binge eating disorders.

    Science.gov (United States)

    Austin, Sue

    2013-06-01

    In this paper the author describes her work with a woman who, in her mid 20s, sought analysis for her non-vomiting binge eating disorder. The paper explores how two aspects of Jung's view of the psyche as healthily dissociable were used to think about the potential for change contained within the explosive, aggressive energies in this patient's bingeing. The resultant approach takes the patient's splitting defences, dissociations and self-destructive behaviour as a point of access to her unconscious. Seen in this way, these behaviours contain the seeds of recovery and are the starting point for analysis rather than defences against it. The paper also brings a number of Jungian and post-Jungian ideas into conversation with aspects of contemporary thinking about subjectivity, identity and the longing for excess developed by Leo Bersani and Judith Butler.

  10. Sex Differences and Correlates of Pain in Patients with Comorbid Obesity and Binge Eating Disorder

    Science.gov (United States)

    Masheb, Robin M.; White, Marney A.; Grilo, Carlos M.

    2016-01-01

    Sex differences and correlates of pain were examined in a sample of patients with comorbid binge eating disorder (BED) and obesity. One hundred fifty-two treatment-seeking patients with BED completed the Brief Pain Inventory. Analysis of covariance was utilized to compare women and men on pain, and correlational analysis, overall and by sex, was performed to examine relationships among pain, eating behaviour and metabolic risk factors. Women reported significantly greater pain severity and pain interference than men. Among women, eating behaviour and metabolic markers were not associated with pain. Among men, however, binge frequency was significantly associated with pain, as was high-density lipoprotein cholesterol and fasting glucose. In sum, while women in this sample had more pain than men, the presence of pain in men was associated with increased behavioural and metabolic risk factors. Findings have clinical implications for the assessment of comorbid pain and obesity-related health risks among individuals with BED. PMID:26841114

  11. Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine

    Science.gov (United States)

    Guerdjikova, Anna I; Mori, Nicole; Casuto, Leah S; McElroy, Susan L

    2016-01-01

    Binge eating disorder (BED) is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. PMID:27143885

  12. Novel pharmacologic treatment in acute binge eating disorder - role of lisdexamfetamine.

    Science.gov (United States)

    Guerdjikova, Anna I; Mori, Nicole; Casuto, Leah S; McElroy, Susan L

    2016-01-01

    Binge eating disorder (BED) is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. PMID:27143885

  13. Shared and unique mechanisms underlying binge eating disordspan>er and addictive disorders.

    Science.gov (United States)

    Schulte, Erica M; Grilo, Carlos M; Gearhardt, Ashley N

    2016-03-01

    Scientific interest in "food addiction" is growing, but the topic remains controversial. One critique of "food addiction" is its high degree of phenotypic overlap with binge eating disorder (BED). In order to examine associations between problematic eating behaviors, such as binge eating and "food addiction," we propose the need to move past examining similarities and differences in symptomology. Instead, focusing on relevant mechanisms may more effectively determine whether "food addiction" contributes to disordered eating behavior for some individuals. This paper reviews the evidence for mechanisms that are shared (i.e., reward dysfunction, impulsivity) and unique for addiction (i.e., withdrawal, tolerance) and eating disorder (i.e., dietary restraint, shape/weight concern) frameworks. This review will provide a guiding framework to outline future areas of research needed to evaluate the validity of the "food addiction" model and to understand its potential contribution to disordered eating. PMID:26879210

  14. Child abuse and neglect: Relations to adolescent binge drinking in the National Longitudinal Study of Adolescent Health (AddHealth) Study

    OpenAIRE

    Shin, Sunny Hyucksun; Edwards, Erika M.; Heeren, Timothy

    2008-01-01

    The purpose of this study was to examine the relationship between child maltreatment and adolescent binge drinking. Given that many victimized children have been maltreated in multiple ways, we examine the effects of co-occurrence of multiple types of maltreatment on adolescent binge drinking. We used the National Longitudinal Study of Adolescent Health (AddHealth), which included a nationally representative sample of adolescents (n = 12,748). Adolescent binge drinking was defined as five or ...

  15. Validation of the portuguese version of the Questionnaire on Eating and Weight Patterns: revised (QEWP-R) for the screening of binge eating disorder

    OpenAIRE

    Borges Maria Beatriz Ferrari; Morgan Christina M; Claudino Angélica M; Silveira Dartiu Xavier da

    2005-01-01

    OBJECTIVE: The present paper describes the validation of the Questionnaire on Eating and Weight Patterns-Revised (QEWP-R) designed for the diagnosis of binge eating disorder (BED) and sub-clinical binge eating. METHODS: 89 overweight women seeking treatment for binge eating and/or obesity were assessed with the Portuguese version of the Questionnaire of Eating and Weight Patterns and were, subsequently, interviewed with the eating disorders module of the Structured Clinical Interview for DSM-...

  16. Binge Drinking in youth: evaluation of a test based in the theory of planned behavior

    OpenAIRE

    Luque, Leticia E.; Gómez, Raúl A.; Cortés Tomás, María T.; Espejo Tort, Begoña; Giménez Costa, José A.

    2014-01-01

    We present the first stage of the construction of a questionnaire that explores cognitive determinants of binge drinking in young subjetcs (16-25 years old), from Cordoba-Argentina. The test – with hundred ten items – including all cognitive determinants, considered by the Theory of Planning Behavior, proposed by I.Azjen. Exploratory factor analyzes indicate that the intensity scales beliefs have two components; the importance of beliefs items were grouped according to such components. Intern...

  17. Review: Jörg Strübing (2005). Pragmatistische Wissenschafts- und Technikforschung. Theorie und Methode

    OpenAIRE

    Lehn, Dirk Vom

    2006-01-01

    Die deutschsprachige Soziologie hat dem Interaktionismus bisher relativ wenig Beachtung geschenkt. Zwar ist der Symbolische Interaktionismus zentraler Bestandteil des Lehrprogramms einer jeden Theorieveranstaltung, doch bleiben theoretische und empirische Entwicklungen des Interaktionismus, die über die Arbeiten von George Herbert MEAD und Herbert BLUMER hinausgehen, häufig unberücksichtigt. Jörg STRÜBINGs Buch rekonstruiert die Entwicklung des Interaktionismus und erläutert seine Bedeutung f...

  18. Adverse Childhood Experiences and Risk of Binge Drinking and Drunkenness in Middle-Aged Finnish Men

    OpenAIRE

    Laura Kauhanen; Janne Leino; Hanna-Maaria Lakka; Lynch, John W.; Jussi Kauhanen

    2011-01-01

    Objective. The purpose of this study was to investigate associations between adverse childhood experiences and binge drinking and drunkenness in adulthood using both historical and recalled data from childhood. Methods. Data on childhood adverse experiences were collected from school health records and questionnaires completed in adulthood. Adulthood data were obtained from the baseline examinations of the male participants (n = 2682) in the Kuopio Ischaemic Heart Disease Risk Factor Study (K...

  19. Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity

    Science.gov (United States)

    Hamelink, Carol; Hampson, Aidan; Wink, David A.; Eiden, Lee E.; Eskay, Robert L.

    2014-01-01

    Binge alcohol consumption in the rat induces substantial neurodegeneration in the hippocampus and entorhinal cortex. Oxidative stress and cytotoxic edema have both been shown to be involved in such neurotoxicity, whereas N-methyl-D-aspartate (NMDA) receptor activity has been implicated in alcohol withdrawal and excitoxic injury. Because the nonpsychoactive cannabinoid cannabidiol (CBD) was previously shown in vitro to prevent glutamate toxicity through its ability to reduce oxidative stress, we evaluated CBD as a neuroprotectant in a rat binge ethanol model. When administered concurrently with binge ethanol exposure, CBD protected against hippocampal and entorhinal cortical neurodegeneration in a dose-dependent manner. Similarly, the common antioxidants butylated hydroxytoluene and α-tocopherol also afforded significant protection. In contrast, the NMDA receptor antagonists dizocilpine (MK-801) and memantine did not prevent cell death. Of the diuretics tested, furosemide was protective, whereas the other two anion exchanger inhibitors, L-644,711 [(R)-(+)-(5,6-dichloro2,3,9,9a-tetrahydro 3-oxo-9a-propyl-1H-fluoren-7-yl)oxy acetic acid] and bumetanide, were ineffective. In vitro comparison of these diuretics indicated that furosemide is also a potent antioxidant, whereas the nonprotective diuretics are not. The lack of efficacy of L-644,711 and bumetanide suggests that the antioxidant rather than the diuretic properties of furosemide contribute most critically to its efficacy in reversing ethanol-induced neurotoxicity in vitro, in our model. This study provides the first demonstration of CBD as an in vivo neuroprotectant and shows the efficacy of lipophilic antioxidants in preventing binge ethanol-induced brain injury. PMID:15878999

  20. Sex Differences and Correlates of Pain in Patients with Comorbid Obesity and Binge Eating Disorder

    OpenAIRE

    Masheb, Robin M.; White, Marney A.; Grilo, Carlos M.

    2016-01-01

    Sex differences and correlates of pain were examined in a sample of patients with comorbid binge eating disorder (BED) and obesity. One hundred fifty-two treatment-seeking patients with BED completed the Brief Pain Inventory. Analysis of covariance was utilized to compare women and men on pain, and correlational analysis, overall and by sex, was performed to examine relationships among pain, eating behaviour and metabolic risk factors. Women reported significantly greater pain severity and pa...

  1. Selected psychological traits and body image characteristics in females suffering from binge eating disorder

    OpenAIRE

    Izydorczyk, Bernadetta

    2013-01-01

    Aim. This paper reports the results of the author’s own research aimed at diagnosing specific psychological (personality) traits and body image characteristics in a population of selected females suffering from binge eating disorder (BED).Method. The methods applied in this research included an inventory (i.e. a Polish version of the Eating Disorder Inventory (EDI) devised by David Garner, Marion P. Olmsted, and Janet Polivy, adapted by Cezary Żechowski; and the Socio-cultural Attitudes towar...

  2. An empirical comparison of atypical bulimia nervosa and binge eating disorder

    OpenAIRE

    Fontenelle L.F.; Mendlowicz M.V.; Moreira R.O.; Appolinario J.C.

    2005-01-01

    The International Classification of Diseases, 10th edition (ICD-10) defines atypical bulimia nervosa (ABN) as an eating disorder that encompasses several different syndromes, including the DSM-IV binge eating disorder (BED). We investigated whether patients with BED can be differentiated clinically from patients with ABN who do not meet criteria for BED. Fifty-three obese patients were examined using the Structured Clinical Interview for DSM-IV and the ICD-10 criteria for eating disorders. Al...

  3. The freshness of Persian Information: the case of Persian Newspapers indexed in Google, Yahoo and Bing

    OpenAIRE

    maryam yaghtin; zohre Honarjooyan; Hajar Sotudeh

    2015-01-01

    Aiming to study the freshness of Persian information, the study attempted to explore the indexing speed of Persian newspapers in Google, Yahoo and Bing. The present study was conducted using a webometric method. The population study comprised all the online newspapers published in Persian. The study sample was identified using a targeted method. It included those Persian newspapers listed on the Magiran database with their electronic versions regularly published on their respective websites. ...

  4. Childhood sexual abuse and adult binge drinking among Kanak women in New Caledonia.

    OpenAIRE

    Hamelin, Christine; Salomon, Christine; Sitta, Rémi; Gueguen, Alice; Cyr, Diane; Lert, France

    2009-01-01

    International audience The long-term consequences of violence against women are poorly documented within the context of political domination, economic inequalities and rapid social change of indigenous communities. Using data from the first population study on violence against women and their consequences on health in New Caledonia, South Pacific, this article investigates the association between childhood sexual abuse and binge drinking among 441 adult Kanak women. Face-to-face standardis...

  5. Alcohol, binge drinking and associated mental health problems in young urban Chileans.

    Directory of Open Access Journals (Sweden)

    Amanda J Mason-Jones

    Full Text Available To explore the link between alcohol use, binge drinking and mental health problems in a representative sample of adolescent and young adult Chileans.Age and sex-adjusted Odds Ratios (OR for four mental wellbeing measures were estimated with separate conditional logistic regression models for adolescents aged 15-20 years, and young adults aged 21-25 years, using population-based estimates of alcohol use prevalence rates from the Chilean National Health Survey 2010.Sixty five per cent of adolescents and 85% of young adults reported drinking alcohol in the last year and of those 83% per cent of adolescents and 86% of young adults reported binge drinking in the previous month. Adolescents who reported binging alcohol were also more likely, compared to young adults, to report being always or almost always depressed (OR 12.97 [95% CI, 1.86-19.54] or to feel very anxious in the last month (OR 9.37 [1.77-19.54]. Adolescent females were more likely to report poor life satisfaction in the previous year than adolescent males (OR 8.50 [1.61-15.78], feel always or almost always depressed (OR 3.41 [1.25-9.58]. Being female was also associated with a self-reported diagnosis of depression for both age groups (adolescents, OR 4.74 [1.49-15.08] and young adults, OR 4.08 [1.65-10.05].Young people in Chile self-report a high prevalence of alcohol use, binge drinking and associated mental health problems. The harms associated with alcohol consumption need to be highlighted through evidence-based prevention programs. Health and education systems need to be strengthened to screen and support young people. Focussing on policy initiatives to limit beverage companies targeting alcohol to young people will also be needed.

  6. A psychological typology of females diagnosed with anorexia nervosa, bulimia nervosa or binge eating disorder

    OpenAIRE

    Bernadetta Izydorczyk

    2015-01-01

    Background The present paper reports the results of research aimed at identifying intra-group differences among females suffering from different eating disorders (anorexia nervosa, bulimia nervosa or binge eating disorder) in terms of the subjects’ psychological traits, adoption of socio-cultural norms (through media pressure, internationalization of norms, and exposure to information concerning body image standards), and the level of body dissatisfaction. The following research question...

  7. A Narrative Review of Binge Eating and Addictive Behaviors: Shared Associations with Seasonality and Personality Factors

    OpenAIRE

    Caroline eDavis

    2013-01-01

    Binge-eating disorder and seasonal affective disorder were first described as clinically relevant conditions in very close temporal proximity a few decades ago. Both disorders have a higher prevalence rate in woman than in men, are characterized by a high proneness-to-stress and manifest heightened responsiveness to high-calorie, hyper-palatable foods. In recent years, a compelling body of evidence suggests that foods high in sugar and fat have the potential to alter brain reward circuitry in...

  8. Food Thought Suppression: A Matched Comparison of Obese Individuals with and without Binge Eating Disorder

    OpenAIRE

    Barnes, Rachel D.; Masheb, Robin M.; Grilo, Carlos M.

    2011-01-01

    Preliminary studies of non-clinical samples suggest that purposely attempting to avoid thoughts of food, referred to as food thought suppression, is related to a number of unwanted eating- and weight-related consequences, particularly in obese individuals. Despite possible implications for the treatment of obesity and eating disorders, little research has examined food thought suppression in obese individuals with binge eating disorder (BED). This study compared food thought suppression in 60...

  9. Pharmacological management of binge eating disorder: current and emerging treatment options

    OpenAIRE

    McElroy SL; Guerdjikova AI; Mori N; O’Melia AM

    2012-01-01

    Susan L McElroy, Anna I Guerdjikova, Nicole Mori, Anne M O'MeliaLindner Center of HOPE, Mason, and Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH, USAAbstract: Growing evidence suggests that pharmacotherapy may be beneficial for some patients with binge eating disorder (BED), an eating disorder characterized by repetitive episodes of uncontrollable consumption of abnormally large amounts of food without inappropriate weight loss behaviors. In th...

  10. A History of Bingeing on Fat Enhances Cocaine Seeking and Taking

    OpenAIRE

    Puhl, Matthew D.; Cason, Angie M.; Wojnicki, Francis H. E.; Corwin, Rebecca L.; Grigson, Patricia S.

    2011-01-01

    Binge eating and substance dependence are disorders characterized by a loss of control over consummatory behaviors. Given the common characteristics of these two types of disorders, it is not surprising that the comorbidity between eating disorders and substance abuse disorders is high (20–40%; Conason et al., 2006). It is unknown, however, whether loss of control in one disorder predisposes an individual to loss of control in the other. The present study, therefore, used a rodent model to te...

  11. Bulimia nervosa, binge eating, and psychogenic vomiting: a controlled treatment study and long term outcome.

    OpenAIRE

    J. H. Lacey

    1983-01-01

    An "epidemic" prevalence of binge eating and vomiting (bulimia nervosa) has been reported, and treatment has been claimed to be difficult. This paper describes a short term outpatient treatment programme of eclectic orientation capable of being conducted by non-specialist staff, under medical supervision, in local centres. The treatment programme was evaluated in a controlled trial and in long term follow up. In 30 women with severe bulimia the treatment programme significantly reduced their ...

  12. Human resting extracellular heat shock protein 72 concentration decreases during the initial adaptation to exercise in a hot, humid environment

    Science.gov (United States)

    Marshall, Helen C.; Ferguson, Richard A.; Nimmo, Myra A.

    2006-01-01

    Heat shock protein (Hsp) 72 is a cytosolic protein that also is present in the circulation. Extracellular Hsp72 (eHsp72) is inducible by exercise and is suggested to act as a danger signal to the immune system. The adaptive response of eHsp72 to repeated exercise-heat exposures in humans remains to be determined. An intracellular animal study found a reduced Hsp72 response, with no change in resting levels, during heat stress after a single day of passive heat acclimation. The current study therefore tested whether adaptations in human eHsp72 levels would similarly occur 24 hours after a single exercise-heat exposure. Seven males completed cycle exercise (42.5% V̇O2peak for 2 hours) in a hot, humid environment (38°C, 60% relative humidity) on each of 2 consecutive days. Blood samples were obtained from an antecubital vein before exercise and 0 hours and 22 hours postexercise for the analysis of eHsp72. Exercise-heat stress resulted in enhanced eHsp72, with a similar absolute increase found on both days (day 1: 1.26 ng/mL [0.80 ng/mL]; day 2: 1.29 ng/mL [1.60 ng/mL]). Resting eHsp72 decreased from rest on day 1 to day 2's 22-hour postexercise sample (P < 0.05). It is suggested that the reduction in resting eHsp72 after 2 consecutive exercise-heat exposures is possibly due to an enhanced removal from the circulation, for either immunoregulatory functions, or for improved cellular stress tolerance in this initial, most stressful period of acclimation. PMID:16817318

  13. Localization of colorectal carcinoma by rhenium-188-labeled B72.3 antibody in xenografted mice

    Energy Technology Data Exchange (ETDEWEB)

    Hosono, Masako N. [Osaka City Univ. (Japan). Medical School; Hosono, Makoto; Zamora, P.O.; Guhlke, S.; Haberberger, T.; Bender, H.; Knapp, F.F.R.; Biersack, H.J.

    1998-04-01

    In order to evaluate the feasibility of {sup 188}Re-labeled antibodies for radioimmunotargeting, monoclonal antibody B72.3, recognizing TAG-72, expressed on the surface membranes of colorectal cancer cells, was directly labeled with {sup 188}Re, obtained from a {sup 188}W/{sup 188}Re generator, using stannous tartrate and compared with {sup 125}I-labeled B72.3. As a control, a human IgG was also radiolabeled with {sup 188}Re and {sup 125}I. Prepared antibodies for {sup 188}Re labeling could be stored as kits. Biodistribution was determined in nude mice inoculated with human colorectal carcinoma LoVo. Labeling efficiency and immunoreactivity of {sup 188}Re-B72.3 were 80.3% and 64.7%, respectively. {sup 188}Re-B72.3 localized specifically in the LoVo tumors. Although the absolute tumor accumulation level of {sup 188}Re-B72.3 was lower than {sup 125}I-B72.3, {sup 188}Re-B72.3 demonstrated higher tumor-to-blood contrast than the {sup 125}I-labeled counterpart, 2.04{+-}0.44 vs. 1.05{+-}0.28 at 96 hours, because of fast clearance from the blood. {sup 188}Re-B72.3 seemed efficient for the imaging and therapy of colorectal carcinoma. (author)

  14. The freshness of Persian Information: the case of Persian Newspapers indexed in Google, Yahoo and Bing

    Directory of Open Access Journals (Sweden)

    maryam yaghtin

    2015-05-01

    Full Text Available Aiming to study the freshness of Persian information, the study attempted to explore the indexing speed of Persian newspapers in Google, Yahoo and Bing. The present study was conducted using a webometric method. The population study comprised all the online newspapers published in Persian. The study sample was identified using a targeted method. It included those Persian newspapers listed on the Magiran database with their electronic versions regularly published on their respective websites. The results revealed that Google outperforms the two other search engines in terms of timely indexing the Persian newspapers. Furthermore, it generally enjoys a more consistent and stable indexing model. Yahoo and Bing are not only slower in indexing the newspapers, but also experience a comparably lower consistency level in their indexing models. Yahoo and Bing show to be comparable in their indexing speeds. In this study, the indexing status of Persian newspapers on different internet search engines was investigated for the first time. Results showed that those accessing these newspapers using internet search engines will have a higher chance of accessing their most updated versions using Google.

  15. Neurofeedback Against Binge Eating: A Randomized Controlled Trial in a Female Subclinical Threshold Sample.

    Science.gov (United States)

    Schmidt, Jennifer; Martin, Alexandra

    2016-09-01

    Brain-directed treatment techniques, such as neurofeedback, have recently been proposed as adjuncts in the treatment of eating disorders to improve therapeutic outcomes. In line with this recommendation, a cue exposure EEG-neurofeedback protocol was developed. The present study aimed at the evaluation of the specific efficacy of neurofeedback to reduce subjective binge eating in a female subthreshold sample. A total of 75 subjects were randomized to EEG-neurofeedback, mental imagery with a comparable treatment set-up or a waitlist group. At post-treatment, only EEG-neurofeedback led to a reduced frequency of binge eating (p = .015, g = 0.65). The effects remained stable to a 3-month follow-up. EEG-neurofeedback further showed particular beneficial effects on perceived stress and dietary self-efficacy. Differences in outcomes did not arise from divergent treatment expectations. Because EEG-neurofeedback showed a specific efficacy, it may be a promising brain-directed approach that should be tested as a treatment adjunct in clinical groups with binge eating. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association. PMID:27121224

  16. Obese Patients With a Binge Eating Disorder Have an Unfavorable Metabolic and Inflammatory Profile.

    Science.gov (United States)

    Succurro, Elena; Segura-Garcia, Cristina; Ruffo, Mariafrancesca; Caroleo, Mariarita; Rania, Marianna; Aloi, Matteo; De Fazio, Pasquale; Sesti, Giorgio; Arturi, Franco

    2015-12-01

    To evaluate whether obese patients with a binge eating disorder (BED) have an altered metabolic and inflammatory profile related to their eating behaviors compared with non-BED obese.A total of 115 White obese patients consecutively recruited underwent biochemical, anthropometrical evaluation, and a 75-g oral glucose tolerance test. Patients answered the Binge Eating Scale and were interviewed by a psychiatrist. The patients were subsequently divided into 2 groups according to diagnosis: non-BED obese (n = 85) and BED obese (n = 30). Structural equation modeling analysis was performed to elucidate the relation between eating behaviors and metabolic and inflammatory profile.BED obese exhibited significantly higher percentages of altered eating behaviors, body mass index (P eating disorder obese also had a worse metabolic and inflammatory profile, exhibiting significantly lower high-density lipoprotein cholesterol levels (P eating behaviors of BED and the metabolic and inflammatory profile.Binge eating disorder obese exhibited an unfavorable metabolic and inflammatory profile, which is related to their characteristic eating habits.

  17. U.S. Hourly Precipitation Data Publication

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This publication contains hourly precipitation amounts obtained from recording rain gages located at National Weather Service, Federal Aviation Administration, and...

  18. U.S. Hourly Precipitation Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hourly Precipitation Data (HPD) is digital data set DSI-3240, archived at the National Climatic Data Center (NCDC). The primary source of data for this file is...

  19. Lateral hypothalamic melanocortin receptor signaling modulates binge-like ethanol drinking in C57BL/6J mice.

    Science.gov (United States)

    Sprow, Gretchen M; Rinker, Jennifer A; Lowery-Gointa, Emily G; Sparrow, Angela M; Navarro, Montserrat; Thiele, Todd E

    2016-07-01

    Binge ethanol drinking is a highly pervasive and destructive behavior yet the underlying neurobiological mechanisms remain poorly understood. Recent work suggests that overlapping neurobiological mechanisms modulate feeding disorders and excessive ethanol intake, and converging evidence indicates that the melanocortin (MC) system may be a promising candidate. The aims of the present work were to examine how repeated binge-like ethanol drinking, using the 'drinking in the dark' (DID) protocol, impacts key peptides within the MC system and if site-specific manipulation of MC receptor (MCR) signaling modulates binge-like ethanol drinking. Male C57BL/6J mice were exposed to one, three or six cycles of binge-like ethanol, sucrose or water drinking, after which brain tissue was processed via immunohistochemistry (IHC) for analysis of key MC peptides, including alpha-melanocyte stimulating hormone (α-MSH) and agouti-related protein (AgRP). Results indicated that α-MSH expression was selectively decreased, while AgRP expression was selectively increased, within specific hypothalamic subregions following repeated binge-like ethanol drinking. To further explore this relationship, we used site-directed drug delivery techniques to agonize or antagonize MCRs within the lateral hypothalamus (LH). We found that the nonselective MCR agonist melanotan-II (MTII) blunted, while the nonselective MCR antagonist AgRP augmented, binge-like ethanol consumption when delivered into the LH. As these effects were region-specific, the present results suggest that a more thorough understanding of the MC neurocircuitry within the hypothalamus will help provide novel insight into the mechanisms that modulate excessive binge-like ethanol intake and may help uncover new therapeutic targets aimed at treating alcohol abuse disorders. PMID:25975524

  20. Larger mid-dorsolateral prefrontal gray matter volume in young binge drinkers revealed by voxel-based morphometry.

    Directory of Open Access Journals (Sweden)

    Sonia Doallo

    Full Text Available Binge drinking or heavy episodic drinking is a high prevalent pattern of alcohol consumption among young people in several countries. Despite increasing evidence that binge drinking is associated with impairments in executive aspects of working memory (i.e. self-ordered working memory, processes known to depend on the mid-dorsolateral prefrontal cortex (Brodmann areas 46 and 9, less is known about the impact of binge drinking on prefrontal gray matter integrity. Here, we investigated the effects of binge drinking on gray matter volume of mid- dorsolateral prefrontal cortex in youths. We used voxel-based morphometry on the structural magnetic resonance images of subjects reporting a persistent (at least three years binge drinking pattern of alcohol use (n = 11; age 22.43 ± 1.03 and control subjects (n = 21; age 22.18 ± 1.08 to measure differences in gray matter volume between both groups. In a region of interest analysis of the mid-dorsolateral prefrontal cortex, after co-varying for age and gender, we observed significantly larger gray matter volume in the left mid-dorsolateral prefrontal cortex (Brodmann areas 46 and 9 in binge drinkers in comparison with control subjects. Furthermore, there was a significant positive correlation between left mid-dorsolateral prefrontal cortex volume and Self-Ordered Pointing Test (SOPT total errors score in binge drinkers. The left mid-dorsolateral prefrontal cortex volume also correlated with the quantity and speed of alcohol intake. These findings indicate that a repeated exposure to alcohol -that does not meet criteria for alcohol dependence- throughout post-adolescent years and young adulthood is linked with structural anomalies in mid-dorsolateral prefrontal regions critically involved in executive aspects of working memory.

  1. Piscivorous fish exhibit temperature-influenced binge feeding during an annual prey pulse.

    Science.gov (United States)

    Furey, Nathan B; Hinch, Scott G; Mesa, Matthew G; Beauchamp, David A

    2016-09-01

    Understanding the limits of consumption is important for determining trophic influences on ecosystems and predator adaptations to inconsistent prey availability. Fishes have been observed to consume beyond what is sustainable (i.e. digested on a daily basis), but this phenomenon of hyperphagia (or binge-feeding) is largely overlooked. We expect hyperphagia to be a short-term (1-day) event that is facilitated by gut volume providing capacity to store consumed food during periods of high prey availability to be later digested. We define how temperature, body size and food availability influence the degree of binge-feeding by comparing field observations with laboratory experiments of bull trout (Salvelinus confluentus), a large freshwater piscivore that experiences highly variable prey pulses. We also simulated bull trout consumption and growth during salmon smolt outmigrations under two scenarios: 1) daily consumption being dependent upon bioenergetically sustainable rates and 2) daily consumption being dependent upon available gut volume (i.e. consumption is equal to gut volume when empty and otherwise 'topping off' based on sustainable digestion rates). One-day consumption by laboratory-held bull trout during the first day of feeding experiments after fasting exceeded bioenergetically sustainable rates by 12- to 87-fold at low temperatures (3 °C) and by  ˜1·3-fold at 20 °C. The degree of binge-feeding by bull trout in the field was slightly reduced but largely in agreement with laboratory estimates, especially when prey availability was extremely high [during a sockeye salmon (Oncorhynchus nerka) smolt outmigration and at a counting fence where smolts are funnelled into high densities]. Consumption by bull trout at other settings were lower and more variable, but still regularly hyperphagic. Simulations demonstrated the ability to binge-feed increased cumulative consumption (16-32%) and cumulative growth (19-110%) relative to only feeding at

  2. Piscivorous fish exhibit temperature-influenced binge feeding during an annual prey pulse

    Science.gov (United States)

    Furey, Nathan B.; Hinch, Scott G.; Mesa, Matthew G.; Beauchamp, David A.

    2016-01-01

    Understanding the limits of consumption is important for determining trophic influences on ecosystems and predator adaptations to inconsistent prey availability. Fishes have been observed to consume beyond what is sustainable (i.e. digested on a daily basis), but this phenomenon of hyperphagia (or binge-feeding) is largely overlooked. We expect hyperphagia to be a short-term (1-day) event that is facilitated by gut volume providing capacity to store consumed food during periods of high prey availability to be later digested.We define how temperature, body size and food availability influence the degree of binge-feeding by comparing field observations with laboratory experiments of bull trout (Salvelinus confluentus), a large freshwater piscivore that experiences highly variable prey pulses. We also simulated bull trout consumption and growth during salmon smolt outmigrations under two scenarios: 1) daily consumption being dependent upon bioenergetically sustainable rates and 2) daily consumption being dependent upon available gut volume (i.e. consumption is equal to gut volume when empty and otherwise ‘topping off’ based on sustainable digestion rates).One-day consumption by laboratory-held bull trout during the first day of feeding experiments after fasting exceeded bioenergetically sustainable rates by 12- to 87-fold at low temperatures (3 °C) and by  ˜1·3-fold at 20 °C. The degree of binge-feeding by bull trout in the field was slightly reduced but largely in agreement with laboratory estimates, especially when prey availability was extremely high [during a sockeye salmon (Oncorhynchus nerka) smolt outmigration and at a counting fence where smolts are funnelled into high densities]. Consumption by bull trout at other settings were lower and more variable, but still regularly hyperphagic.Simulations demonstrated the ability to binge-feed increased cumulative consumption (16–32%) and cumulative growth (19–110%) relative to only feeding at

  3. 10 CFR 63.72 - Construction records.

    Science.gov (United States)

    2010-01-01

    ... maintain records of construction of the geologic repository operations area at the Yucca Mountain site in a..., and sequence of work; (6) Construction problems; (7) Anomalous conditions encountered; (8) Instrument... 10 Energy 2 2010-01-01 2010-01-01 false Construction records. 63.72 Section 63.72 Energy...

  4. 50 CFR 27.72 - Audio equipment.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Audio equipment. 27.72 Section 27.72 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE... Audio equipment. The operation or use of audio devices including radios, recording and playback...

  5. 36 CFR 72.48 - Federal coordination.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Federal coordination. 72.48... and Innovation § 72.48 Federal coordination. Applicants requesting UPARR assistance under one of the three grant categories shall investigate the possibilities of administrative and/or funding...

  6. 10 CFR 72.162 - Test control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Test control. 72.162 Section 72.162 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL... Test control. The licensee, applicant for a license, certificate holder, and applicant for a CoC...

  7. 10 CFR 72.152 - Document control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Document control. 72.152 Section 72.152 Energy NUCLEAR... Document control. The licensee, applicant for a license, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and...

  8. 10 CFR 72.146 - Design control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Design control. 72.146 Section 72.146 Energy NUCLEAR... Design control. (a) The licensee, applicant for a license, certificate holder, and applicant for a CoC... shall establish measures for the identification and control of design interfaces and for...

  9. 44 CFR 72.3 - Fee schedule.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Fee schedule. 72.3 Section 72.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND... initial fee, if necessary, will be published as a notice in the Federal Register. (b) For requests...

  10. 10 CFR 72.172 - Corrective action.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Corrective action. 72.172 Section 72.172 Energy NUCLEAR... Corrective action. The licensee, applicant for a license, certificate holder, and applicant for a CoC shall... that the cause of the condition is determined and corrective action is taken to preclude...

  11. 27 CFR 72.39 - Final action.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Final action. 72.39... Remission or Mitigation of Forfeitures § 72.39 Final action. (a) Petitions for remission or mitigation of forfeiture. (1) The Director shall take final action on any petition filed pursuant to these...

  12. 7 CFR 1212.72 - Confidential treatment.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Confidential treatment. 1212.72 Section 1212.72 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HONEY PACKERS AND...

  13. 9 CFR 72.25 - Dipping methods.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Dipping methods. 72.25 Section 72.25 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TEXAS (SPLENETIC) FEVER...

  14. 34 CFR 5.72 - Records available.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Records available. 5.72 Section 5.72 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC PURSUANT TO PUB... projects, such as films, computer software, other copyrightable materials and reports of inventions,...

  15. 10 CFR 72.4 - Communications.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Communications. 72.4 Section 72.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL... Communications. Except where otherwise specified, all communications and reports concerning the regulations...

  16. 36 CFR 72.73 - Residency requirements.

    Science.gov (United States)

    2010-07-01

    ... Section 72.73 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR URBAN PARK AND RECREATION RECOVERY ACT OF 1978 Post-Completion Compliance Responsibilities § 72.73 Residency... assistance. This prohibition applies to both regularly scheduled and special events. The general...

  17. 7 CFR 996.72 - Confidential information.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Confidential information. 996.72 Section 996.72... Confidential information. All reports and records furnished or submitted by handlers and importers to USDA which include data or information constituting a trade secret or disclosing a trade position,...

  18. 5 CFR 7.2 - Reemployment rights.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Reemployment rights. 7.2 Section 7.2... Reemployment rights. OPM, whenever it determines it to be necessary, shall prescribe regulations governing the..., granting, and exercise of rights to reemployment in the agencies from which employees are released....

  19. Hourly Electricity Demand in Italian Market

    OpenAIRE

    Simona Bigerna; Bollino, Carlo Andrea

    2013-01-01

    In the existing literature only recently there has been attention to consumer demand for electricity in organized markets. In this paper we assume a theoretical model of demand behavior and we estimate a complete system for hourly electricity demand. We use individual demand bid data in the Italian Power Exchange (IPEX). The novel contribution of this paper is twofold. Firstly we construct a theory based behavioral model of hourly electricity demand for agents acting in the Italian market; se...

  20. Longer opening hours, alcohol consumption and health

    OpenAIRE

    Green, Colin Peter; Hollingsworth, Bruce Philip; Navarro Paniagua, Maria

    2015-01-01

    Two related issues in public policy with respect to alcohol are how increased availability influences consumption and what effect excess consumption has on individual health outcomes. This paper examines one particular source of variation in availability, bar opening hours, and how this influences alcohol consumption, physical and mental health. We focus on the extension of opening hours in England and Wales that occurred in 2005. We demonstrate a marked increase in consumption, which appears...

  1. Binge Drinking among Men Who Have Sex with Men and Transgender Women in San Salvador: Correlates and Sexual Health Implications.

    Science.gov (United States)

    Peacock, Erin; Andrinopoulos, Katherine; Hembling, John

    2015-08-01

    High rates of heavy alcohol use among men who have sex with men (MSM) and transgender women (TW) have been linked to increased vulnerability for HIV and poor mental health. While theories explaining elevated drinking levels among sexual minorities have been forwarded, few investigations have assessed the potential pathways using empirical data, particularly with an explicit focus on self-stigma and among MSM and TW in low- and middle-income countries. This study examined the relationship between stigma-related stress (specifically, self-stigma and concealment of one's sexual orientation) and binge drinking in a sample of MSM and TW (n = 670) in San Salvador, El Salvador, recruited using respondent-driven sampling. Levels of alcohol consumption among participants were high: only 39 % of the sample did not drink alcohol or did not binge drink, while 34 % engaged in binge drinking at least weekly. Among MSM, high self-stigma was associated with binge drinking at least weekly (adjusted relative risk ratio (aRRR) = 2.1, p < 0.05). No such relationship was found with less than weekly binge drinking. Among both MSM and TW, having a female partner was associated with binge drinking less than weekly (aRRR = 3.3, p < 0.05) and binge drinking at least weekly (aRRR = 3.4, p < 0.05), while disclosure of sexual orientation to multiple types of people was associated with binge drinking less than weekly (aRRR = 2.9 for disclosure to one-two types of people, p < 0.01; aRRR = 4.0 for disclosure to three-nine types of people, p < 0.01). No such relationship was found with at least weekly binge drinking. Binge drinking at least weekly was marginally associated with a number of sexual health outcomes, including high number of lifetime partners (adjusted odds ratio (aOR) = 1.7, p < 0.10), inconsistent condom use with a non-regular partner (aOR = 0.5, p < 0.10), and decreased intention to test for HIV in the next 12 months (a

  2. Adolescent, but not adult, binge ethanol exposure leads to persistent global reductions of choline acetyltransferase expressing neurons in brain.

    Directory of Open Access Journals (Sweden)

    Ryan P Vetreno

    Full Text Available During the adolescent transition from childhood to adulthood, notable maturational changes occur in brain neurotransmitter systems. The cholinergic system is composed of several distinct nuclei that exert neuromodulatory control over cognition, arousal, and reward. Binge drinking and alcohol abuse are common during this stage, which might alter the developmental trajectory of this system leading to long-term changes in adult neurobiology. In Experiment 1, adolescent intermittent ethanol (AIE; 5.0 g/kg, i.g., 2-day on/2-day off from postnatal day [P] 25 to P55 treatment led to persistent, global reductions of choline acetyltransferase (ChAT expression. Administration of the Toll-like receptor 4 agonist lipopolysaccharide to young adult rats (P70 produced a reduction in ChAT+IR that mimicked AIE. To determine if the binge ethanol-induced ChAT decline was unique to the adolescent, Experiment 2 examined ChAT+IR in the basal forebrain following adolescent (P28-P48 and adult (P70-P90 binge ethanol exposure. Twenty-five days later, ChAT expression was reduced in adolescent, but not adult, binge ethanol-exposed animals. In Experiment 3, expression of ChAT and vesicular acetylcholine transporter expression was found to be significantly reduced in the alcoholic basal forebrain relative to moderate drinking controls. Together, these data suggest that adolescent binge ethanol decreases adult ChAT expression, possibly through neuroimmune mechanisms, which might impact adult cognition, arousal, or reward sensitivity.

  3. Lisdexamfetamine Dimesylate for Adults with Moderate to Severe Binge Eating Disorder: Results of Two Pivotal Phase 3 Randomized Controlled Trials

    Science.gov (United States)

    McElroy, Susan L; Hudson, James; Ferreira-Cornwell, M Celeste; Radewonuk, Jana; Whitaker, Timothy; Gasior, Maria

    2016-01-01

    The efficacy and safety of lisdexamfetamine dimesylate (LDX) vs placebo in binge eating disorder (BED) was evaluated in two multicenter, double-blind, placebo-controlled trials. Adults (study 1, n=383; study 2, n=390) meeting DSM-IV-TR BED criteria were randomized (1:1) to placebo or LDX (50 or 70 mg/day) dose titration; optimized doses were maintained to the end of double-blind treatment (week 12/early termination). Change from baseline in binge eating days/week at weeks 11−12 (primary efficacy endpoint) was assessed with mixed-effects models for repeated measures. Secondary endpoints related to binge eating and medical parameters, safety, and treatment compliance were also assessed. Least squares mean (95% CI) treatment differences for change from baseline binge eating days/week at weeks 11–12 significantly favored LDX (study 1: –1.35 [–1.70, –1.01] study 2: –1.66 [–2.04, –1.28] both Peating days/week from baseline and improving binge eating–related key secondary endpoints. Safety results appear consistent with the known safety profile of LDX. PMID:26346638

  4. Comparing cognitive behavioural therapy for eating disorders integrated with behavioural weight loss therapy to cognitive behavioural therapy-enhanced alone in overweight or obese people with bulimia nervosa or binge eating disorder: study protocol for a randomised controlled trial

    OpenAIRE

    Palavras, Marly Amorim; Hay, Phillipa; Touyz, Stephen; Sainsbury, Amanda; da Luz, Felipe; Swinbourne, Jessica; Estella, Nara Mendes; Claudino, Angélica

    2015-01-01

    Background Around 40 % of individuals with eating disorders of recurrent binge eating, namely bulimia nervosa and binge eating disorder, are obese. In contrast to binge eating disorder, currently there is no evidence base for weight management or weight loss psychological therapies in the treatment of bulimia nervosa despite their efficacy in binge eating disorder. Thus, a manualised therapy called HAPIFED (Healthy APproach to weIght management and Food in Eating Disorders) has been developed...

  5. How extreme is extreme hourly precipitation?

    Science.gov (United States)

    Papalexiou, Simon Michael; Dialynas, Yannis G.; Pappas, Christoforos

    2016-04-01

    The importance of accurate representation of precipitation at fine time scales (e.g., hourly), directly associated with flash flood events, is crucial in hydrological design and prediction. The upper part of a probability distribution, known as the distribution tail, determines the behavior of extreme events. In general, and loosely speaking, tails can be categorized in two families: the subexponential and the hyperexponential family, with the first generating more intense and more frequent extremes compared to the latter. In past studies, the focus has been mainly on daily precipitation, with the Gamma distribution being the most popular model. Here, we investigate the behaviour of tails of hourly precipitation by comparing the upper part of empirical distributions of thousands of records with three general types of tails corresponding to the Pareto, Lognormal, and Weibull distributions. Specifically, we use thousands of hourly rainfall records from all over the USA. The analysis indicates that heavier-tailed distributions describe better the observed hourly rainfall extremes in comparison to lighter tails. Traditional representations of the marginal distribution of hourly rainfall may significantly deviate from observed behaviours of extremes, with direct implications on hydroclimatic variables modelling and engineering design.

  6. Long working hours and alcohol use

    DEFF Research Database (Denmark)

    Virtanen, Marianna; Jokela, Markus; Nyberg, Solja T;

    2015-01-01

    OBJECTIVE: To quantify the association between long working hours and alcohol use. DESIGN: Systematic review and meta-analysis of published studies and unpublished individual participant data. DATA SOURCES: A systematic search of PubMed and Embase databases in April 2014 for published studies......, supplemented with manual searches. Unpublished individual participant data were obtained from 27 additional studies. REVIEW METHODS: The search strategy was designed to retrieve cross sectional and prospective studies of the association between long working hours and alcohol use. Summary estimates were...... countries. The pooled maximum adjusted odds ratio for the association between long working hours and alcohol use was 1.11 (95% confidence interval 1.05 to 1.18) in the cross sectional analysis of published and unpublished data. Odds ratio of new onset risky alcohol use was 1.12 (1.04 to 1...

  7. Longer Opening Hours for the Library

    CERN Multimedia

    2001-01-01

    The scientific information service. The CERN library is open 24 hours a day, 365 days a year. So how, you might be wondering, can they improve on that? The answer is in the detail. Although you can already use the library whenever you want, items can only be checked out when the front desk is staffed. A decision taken last week by the Scientific Information Policy Board now means that there will someone at the desk through out CERN's official working hours, with an extra 90 minutes at the end of the day so that people can check out material on their way home. In other words, the library will be open from 8:30 to 19:00, Monday to Friday. The library continues, of course, to be open 24 hours a day, all year round, and services provided via the digital library remain at your disposal day and night: http://library.cern.ch

  8. Constructing gridded hourly temperature data sets

    Science.gov (United States)

    Dumitrescu, Alexandru

    2013-04-01

    Air temperature is the main climatological element, with major impact on the earth-atmosphere energy balance. The characteristics of the surface air temperature in locations without meteorological measurements are obtained using spatio-temporal interpolation techniques. Gridded surface meteorological data are essential for evaluating the performance of regional climate models (RCMs), for applying Statistical Downscaling (SD) methods and as input data for hydrological models. In this study we proposed a methodolgy for interpolating hourly surface temperatures. Three gridding methods are compared. A two-step multivariate gridding approach was used. First we interpolated the hourly normal maps, considered as multiannual average (1961-2010), of air temperature for each hour (4 meteorological terms) of a standard year (366 days). In this step, the Residual Kriging method was used with potential predictors derived from DEM and Landcover Corinne. For interpolating the residuals of the regression model we tested 3 gridding methods: Multiquadratic (MQ), Ordinary Kriging (OK) and 3D Kriging (using time as a third dimension). In the second step, we calculated the anomalies of each hour, day, year for the period 1961-2010. The anomalies were interpolated using the same methods applied for gridding regression residuals. The final hourly surface air temperature maps were obtained by summing the maps from first step with the anomlies map. The main data used in this work were the hourly air temperatures of the 4 observation terms (01, 07, 13, 19), measured between 1961-2010 at the weather stations of the Romanian Meteorological Administration. The predictors were derived from SRTM (Shuttle Radar Topography Mission) DEM and from CORINE Land Cover 2000 product. The gridding was performed in a Romanian National Grid (Stereo 70), at 1 km2 spatial resolution, using R language. The study has been financed by the research project Changes in climate extremes and associated impact in

  9. Body Dissatisfaction, Living Away from Parents, and Poor Social Adjustment Predict Binge Eating Symptoms in Young Women Making the Transition to University

    Science.gov (United States)

    Barker, Erin T.; Galambos, Nancy L.

    2007-01-01

    The current study explored how body dissatisfaction and challenges associated with the transition to university predicted symptoms of binge eating. Participants were 101 female full-time first-year university students (M=18.3 years of age; SD=0.50) who completed a background questionnaire and a web-based daily checklist assessing binge eating.…

  10. The effects of low to moderate alcohol consumption and binge drinking in early pregnancy on behaviour in 5-year-old children

    DEFF Research Database (Denmark)

    Skogerbø, Å; Kesmodel, Ulrik Schiøler; Denny, C H;

    2013-01-01

    To examine the effects of low to moderate maternal alcohol consumption and binge drinking in early pregnancy on behaviour in children at the age of 5 years.......To examine the effects of low to moderate maternal alcohol consumption and binge drinking in early pregnancy on behaviour in children at the age of 5 years....

  11. Is alcohol binge drinking in early and late pregnancy associated with behavioural and emotional development at age 7 years?

    DEFF Research Database (Denmark)

    Niclasen, Janni; Andersen, Anne-Marie Nybo; Strandberg-Larsen, Katrine;

    2014-01-01

     = 37,315). After adjustment for maternal education, psychiatric diagnoses, age and smoking, children exposed to binge drinking in early and late pregnancy had significantly higher mean externalizing scores at age seven than unexposed children, an effect albeit much less for early binge drinking...

  12. Avoiding Lawsuits for Wage and Hour Violations.

    Science.gov (United States)

    Silberman, Cherie L

    2016-01-01

    Due to the highly technical language in the wage and hour laws and regulations, employers often find that they have unknowingly violated the Fair Labor Standards Act (FLSA). This can occur because employers have improperly classified an employee as exempt or because employers do not realize that certain time should be paid in full. Improperly classifying employees as exempt or failing to compensate nonexempt employees for all time worked can lead to costly lawsuits, audits, or enforcement actions by the Wage and Hour Division of the Department of Labor. This article discusses the most common FLSA exemptions and provides best practices to avoid liability under the FLSA.

  13. Limits of Rush Hour Logic Complexity

    OpenAIRE

    Tromp, John; Cilibrasi, Rudi

    2005-01-01

    Rush Hour Logic was introduced in [Flake&Baum99] as a model of computation inspired by the ``Rush Hour'' toy puzzle, in which cars can move horizontally or vertically within a parking lot. The authors show how the model supports polynomial space computation, using certain car configurations as building blocks to construct boolean circuits for a cpu and memory. They consider the use of cars of length 3 crucial to their construction, and conjecture that cars of size 2 only, which we'll call `Si...

  14. 42 CFR 460.72 - Physical environment.

    Science.gov (United States)

    2010-10-01

    ... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. A copy of the Code is available for inspection at the CMS... Interim Amendment 00-1(101) for incorporation by reference in accordance with 5 U.S.C. 552(a) and 1 CFR... 42 Public Health 4 2010-10-01 2010-10-01 false Physical environment. 460.72 Section 460.72...

  15. Binge drinking during pregnancy and risk of seizures in childhood: a study based on the Danish National Birth Cohort

    DEFF Research Database (Denmark)

    Sun, Yuelian; Strandberg-Larsen, Katrine; Vestergaard, Mogens;

    2009-01-01

    Seizures are often found in children with fetal alcohol syndrome, but it is not known whether binge drinking during pregnancy by nonalcoholic women is associated with an increased risk of seizure disorders in children. The authors conducted a population-based cohort study of 80,526 liveborn...... singletons in the Danish National Birth Cohort (1996-2002). Information on maternal binge drinking (intake of > or = 5 drinks on a single occasion) was collected in 2 computer-assisted telephone interviews during pregnancy. Children were followed for up to 8 years. Information on neonatal seizures, epilepsy......, and febrile seizures was retrieved from the Danish National Hospital Register. Results showed that exposure to binge drinking episodes during pregnancy was not associated with an increased risk of seizure disorders in children, except for those exposed at 11-16 gestational weeks. These children had a 3...

  16. Binge drinking among gay, and lesbian youths: The role of internalized sexual stigma, self-disclosure, and individuals' sense of connectedness to the gay community.

    Science.gov (United States)

    Baiocco, Roberto; D'Alessio, Maria; Laghi, Fiorenzo

    2010-10-01

    We examined the prevalence of binge drinking among lesbian and gay (LG) youths, and evaluated whether experiences such as internalized sexual stigma, the experience of "coming out" to family and friends, and the individuals' sense of "connectedness" to the gay community could be associated with alcohol abuse. The research involved 119 gay (58.9%) and 83 lesbian (41.1%) Italian youths (18 to 24 years old). According to previous research, youths were categorized in non-drinkers, social, binge and heavy drinkers. Results showed that the estimated percentage of binge drinking among gay and lesbian youths is 43.6%. The survey revealed that social, binge, and heavy drinkers differ in terms of some drinking variables, internalized sexual stigma, family and peer self-disclosure, and connectedness gay community. Implications for the prevention of binge drinking in LG youths are currently under discussion even if further investigation is urgently needed. PMID:20584573

  17. A comparative analysis of Type 2 diabetes and binge eating disorder in a bariatric sample.

    Science.gov (United States)

    Webb, Jennifer B; Applegate, Katherine L; Grant, John P

    2011-08-01

    An emerging literature has illuminated an important link between Type 2 diabetes mellitus (DM) and binge eating disorder (BED) within obese cohorts. However, prior work has not examined this relationship specifically in a weight loss surgery (WLS) sample or fully explored potential psychosocial factors associated with this co-occurrence. Therefore, the present investigation sought to identify socio-demographic (i.e. age, education, BMI, ethnicity, gender, age of obesity onset) and psychological (i.e. depressive symptoms, hedonic hunger/food locus of control beliefs, severity of binge eating-related cognitions) correlates of the co-occurrence of Type 2 DM and BED among bariatric surgery candidates. An archival sample of 488 patients seeking surgical treatment for clinical obesity completed a standard battery of pre-operative psychosocial measures. The presence of BED was evaluated using a semi-structured clinical interview based on the DSM-IV TR (APA, 2000) and was further corroborated by responses on the Questionnaire on Eating and Weight Patterns-Revised (QEWP-R; Spitzer, Yanovski, & Marcus, 1993). Results indicated that 8.2% of the sample was classified as having both Type 2 DM and BED concurrently. A multivariate logistic regression model revealed that in addition to other psychological (e.g., binge eating-related cognitions, hedonic hunger) and demographic variables (i.e. male gender), African American ethnicity (OR=3.3: 1.41-7.73) was a particularly robust indicator of comorbid status. Findings support and extend previous health disparity research urging greater attention to the needs of traditionally underserved, at-risk populations seeking treatment for obesity complicated by dysregulated eating and metabolism. Additionally, these preliminary results underscore the relevance of considering the potential benefits of providing quality comprehensive pre- and post-operative psychological care among bariatric patients towards optimizing both short- and long

  18. Estimator's electrical man-hour manual

    CERN Document Server

    Page, John S

    1999-01-01

    This manual's latest edition continues to be the best source available for making accurate, reliable man-hour estimates for electrical installation. This new edition is revised and expanded to include installation of electrical instrumentation, which is used in monitoring various process systems.

  19. Analysis of The Story of An Hour

    Institute of Scientific and Technical Information of China (English)

    曹玉琴

    2014-01-01

    By reading the short story The Story of An Hour written by Kate Chopin, we tried to probe the story better by analyz-ing five characters, plots of the story and rhetorical devices, such as irony and symbolism. With originality and profound mean-ings, the novel about the small theme of family life had a wide variety of social significance.

  20. 10 CFR 26.205 - Work hours.

    Science.gov (United States)

    2010-01-01

    ... no reasonable opportunities or accommodations appropriate for restorative sleep. (1) Shift turnover... extended tests of safety systems and components. Licensees may not exclude work hours worked during... opportunity and accommodations for restorative sleep (e.g., a nap). (3) Beginning or resuming duties...

  1. Installation Service - Changes in opening hours

    CERN Multimedia

    GS Department

    2010-01-01

    For organizational matters, please note that, as from 15 March 2010, the Installation Service will have wen opening hours. The new schedule will be from 14:00 to 17:00 (Monday to Friday). Contact persons are: Martine Briant, Karine Robert and Claudia Bruggmann. The office address remains 73-3-014. Installation Service

  2. Long working hours and alcohol use

    DEFF Research Database (Denmark)

    Virtanen, Marianna; Jokela, Markus; Nyberg, Solja T;

    2015-01-01

    OBJECTIVE: To quantify the association between long working hours and alcohol use. DESIGN: Systematic review and meta-analysis of published studies and unpublished individual participant data. DATA SOURCES: A systematic search of PubMed and Embase databases in April 2014 for published studies, su...

  3. Electoral (Amendment) (Hours of Polling) Bill 2013

    DEFF Research Database (Denmark)

    Butler, Graham; Hunt, Brian; Doyle, Andrew

    2013-01-01

    Private Members' Bill (legislation) introduced in Dáil Éireann (House of Deputies), Houses of the Oireachtas (Parliament of Ireland). An Act to set voting hours for Dáil Elections, Dáil Bye-Elections, Presidential Elections, European Parliament Elections, Local Government Elections and Referenda ...

  4. The History of the Student Credit Hour.

    Science.gov (United States)

    Shedd, Jessica M.

    2003-01-01

    Traces the history of the student credit hour, designed at the end of the 19th century to translate high school work to college admissions officers. It was expanded to higher education to record elective course work and became widespread in response to calls to document workload and institutional productivity. (SLD)

  5. Tolerance to 3,4-Methylenedioxymethamphetamine (MDMA) in Rats Exposed to Single High-Dose Binges

    OpenAIRE

    Baumann, Michael H.; Clark, Robert D; Franken, Frederick H.; Rutter, John J.; Rothman, Richard B.

    2008-01-01

    3,4-Methylenedioxymethamphetamine (MDMA or Ecstasy) stimulates the transporter-mediated release of monoamines, including serotonin (5-HT). High-dose exposure to MDMA causes persistent 5-HT deficits (e.g., depletion of brain 5-HT) in animals, yet the functional and clinical relevance of such deficits are poorly defined. Here we examine functional consequences of MDMA-induced 5-HT depletions in rats. Male rats received binges of 3 ip injections of MDMA or saline, one injection every 2 h; MDMA w...

  6. Antecedent life events of binge-eating disorder

    OpenAIRE

    Pike, Kathleen M.; Wilfley, Denise; Hilbert, Anja; Fairburn, Christopher G.; Dohm, Faith-Anne; Striegel-Moore, Ruth H

    2006-01-01

    The present study investigated the occurrence of life events preceding the onset of disturbed eating in binge-eating disorder (BED). In a case-control design, 162 matched pairs of black and white women with BED and women with no current psychiatric disorder, and 107 matched pairs of women with BED and a current general psychiatric disorder were recruited from the community for the New England Women's Health Project. Life events in the year before the onset of disturbed eating were assessed re...

  7. New levels and transitions in 72Ge following the decay of 72Ga

    Institute of Scientific and Technical Information of China (English)

    李燕; 沈水法; 石双惠; 顾嘉辉; 刘静怡; 徐慧

    2005-01-01

    The decay of 72Ga has been investigated by means of γ-ray spectroscopy. The 72Ga nuclei were produced through the 71Ga(n, γ)72Ga reaction. The Compton-suppressed spectrometer and high-purity Ge detectors have been used singly and in coincidence, separately, to study γ-rays in theβ- decay of 72Ga to 72Ge. Ninety-three events of γ-rays were reported, of which 7 were observed for the first time. A decay scheme of 72Ga including 4 new levels is proposed which accommodates 87 of these transitions. Spins and parities for new levels are proposed from calculated log ft values,modes on the observed decay, and some nuclear reaction experimental results.

  8. Chromatographic Separation of Selenium and Arsenic: A Potential 72Se/72As Generator

    Science.gov (United States)

    Wycoff, Donald E.; Gott, Matthew D.; DeGraffenreid, Anthony J.; Morrow, Ryan P.; Sisay, Nebiat; Embree, Mary F.; Ballard, Beau; Fassbender, Michael E.; Cutler, Cathy S.; Ketring, Alan R.; Jurisson, Silvia S.

    2014-01-01

    Summary An anion exchange method was developed to separate selenium and arsenic for potential utility in a 72Se/72As generator. The separation of the daughter 72As from the 72Se parent is based on the relative acid-base behavior of the two oxo-anions in their highest oxidation states. At pH 1.5, selenate is retained on strongly basic anion exchange resin as HSeO4− and SeO42−, while neutral arsenic acid, H3AsO4, is eluted. PMID:24679827

  9. Chromatographic separation of selenium and arsenic: A potential (72)Se/(72)As generator.

    Science.gov (United States)

    Wycoff, Donald E; Gott, Matthew D; DeGraffenreid, Anthony J; Morrow, Ryan P; Sisay, Nebiat; Embree, Mary F; Ballard, Beau; Fassbender, Michael E; Cutler, Cathy S; Ketring, Alan R; Jurisson, Silvia S

    2014-05-01

    An anion exchange method was developed to separate selenium and arsenic for potential utility in a (72)Se/(72)As generator. The separation of the daughter (72)As from the (72)Se parent is based on the relative acid-base behavior of the two oxo-anions in their highest oxidation states. At pH 1.5, selenate is retained on strongly basic anion exchange resin as HSeO4(-) and SeO4(2-), while neutral arsenic acid, H3AsO4, is eluted. PMID:24679827

  10. Chromatographic Separation of Selenium and Arsenic: A Potential 72Se/72As Generator

    OpenAIRE

    Wycoff, Donald E.; Gott, Matthew D.; DeGraffenreid, Anthony J.; Morrow, Ryan P.; Sisay, Nebiat; Embree, Mary F.; Ballard, Beau; Fassbender, Michael E.; Cutler, Cathy S.; Ketring, Alan R.; Jurisson, Silvia S.

    2014-01-01

    An anion exchange method was developed to separate selenium and arsenic for potential utility in a 72Se/72As generator. The separation of the daughter 72As from the 72Se parent is based on the relative acid-base behavior of the two oxo-anions in their highest oxidation states. At pH 1.5, selenate is retained on strongly basic anion exchange resin as HSeO4− and SeO42−, while neutral arsenic acid, H3AsO4, is eluted.

  11. Predictors of weekly alcohol drinking and alcohol-related problems in binge-drinking undergraduates.

    Science.gov (United States)

    Motos Sellés, Patricia; Cortés Tomás, María Teresa; Giménez Costa, José Antonio; Cadaveira Mahía, Fernando

    2015-01-01

    The important implications generated by binge drinking among university students justify the interest to determine which factors predict its occurrence. Specifically, this study aims to assess the role of personality and drinking onset in predicting weekly alcohol consumption, and the impact of the whole set of variables in predicting the number of consequences associated with consumption in undergraduates. Two hundred and thirteen freshmen who were intensive consumers (binge drinkers) from the University Complutense of Madrid were evaluated. All of them filled in a self-registration of consumption, the BIS-11, the NEO-FFI and the IECI consequences associated with intake. The hierarchical regression analysis shows that the drinking onset appears to be a relevant predictor variable in explaining weekly consumption and the number of consequences. The same can be said of the weekly consumption variable with regard to the number of consequences. In general, the influence of personality is quite limited. It is interesting to point out that responsibility and impulsivity, along with age, explain most of the weekly consumption behavior among males. With respect to the consequences of consumption, only impulsivity and neuroticism contribute to explain them, but with less strength than age and weekly consumption. Our results justify the need to plan tighter interventions and consider new predictors that help to explain further weekly consumption in women. PMID:26132301

  12. The association between emotions and eating behaviour in an obese population with binge eating disorder.

    Science.gov (United States)

    Nicholls, W; Devonport, T J; Blake, M

    2016-01-01

    There is utility in understanding the antecedents of binge eating (BE), with a view to explaining poorer weight loss treatment responses in this subgroup. A systematic review was completed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines with the aim of exploring associations between emotions and eating behaviour in a population affected by obesity and binge eating disorder (BED). A comprehensive literature search of four electronic databases (2004-2014) yielded 15 studies for inclusion. Included studies performed poorly on data quality analysis with respect to controlling for confounding variables, and sample size. Included papers largely focused on negative emotions as antecedents of BE; depression was consistently associated with a BED-obese classification and BE. Negative mood, sadness, tension and instability of emotions were found to be antecedents of BE in an adult BED-obese sample. However, findings were mixed regarding the role of stress, anger and positive emotions within the BED-obese population. Recommendations are presented for the identification of BED, and ecologically valid experimental designs that further understanding of the complex and varied emotions that associate with BE. The implications of these and other limitations for both researchers and practitioners are discussed. The paper concludes with recommendations for future research alongside suggestions for practitioners. © 2015 World Obesity. PMID:26644173

  13. The effect of suppressing negative emotions on eating behavior in binge eating disorder.

    Science.gov (United States)

    Dingemans, Alexandra E; Martijn, Carolien; Jansen, Anita T M; van Furth, Eric F

    2009-02-01

    Overeating may be a consequence of the suppression of negative emotions, by depleting self-control resources. This experiment investigated whether (a) there is a causal relationship between the suppression of negative emotions, negative mood, and overeating in people with binge eating disorder (BED) and whether (b) this relationship is increased in depressed people with BED. Sixty-six women with (full and sub-threshold) BED were shown an upsetting movie and then asked either to suppress their emotions or to react naturally. Subsequently, everyone participated in a taste task. After a decline, initial mood before watching the movie was restored after eating. Depressive symptomatology was positively correlated with caloric intake. Within the clinically depressed (Beck Depression Inventory-score>19) BED group, those who were most affected by the negative mood induction consumed the most calories. No differences were found between the two conditions with regard to caloric intake. No interaction effect was found between depressive symptoms and mood suppression. The hypothesis that suppression of negative emotion leads to overeating in (depressed) binge eaters was not born out. Overeating may serve as a means to (temporary) repair negative mood. PMID:18778742

  14. Visual attentional bias for food in adolescents with binge-eating disorder.

    Science.gov (United States)

    Schmidt, Ricarda; Lüthold, Patrick; Kittel, Rebekka; Tetzlaff, Anne; Hilbert, Anja

    2016-09-01

    Evidence suggests that adults with binge-eating disorder (BED) are prone of having their attention interfered by food cues, and that food-related attentional biases are associated with calorie intake and eating disorder psychopathology. For adolescents with BED experimental evidence on attentional processing of food cues is lacking. Using eye-tracking and a visual search task, the present study examined visual orienting and disengagement processes of food in youth with BED. Eye-movement data and reaction times were recorded in 25 adolescents (12-20 years) with BED and 25 controls (CG) individually matched for sex, age, body mass index, and socio-economic status. During a free exploration paradigm, the BED group showed a greater gaze duration bias for food images than the CG. Groups did not differ in gaze direction biases. In a visual search task, the BED group showed a greater detection bias for food targets than the CG. Group differences were more pronounced for personally attractive than unattractive food images. Regarding clinical associations, only in the BED group the gaze duration bias for food was associated with increased hunger and lower body mass index, and the detection bias for food targets was associated with greater reward sensitivity. The study provided first evidence of an attentional bias to food in adolescents with BED. However, more research is needed for further specifying disengagement and orienting processes in adolescent BED, including overt and covert attention, and their prospective associations with binge-eating behaviors and associated psychopathology. PMID:27267318

  15. Night eating patterns and chronotypes: a correlation with binge eating behaviors.

    Science.gov (United States)

    Harb, Ana; Levandovski, Rosa; Oliveira, Ceres; Caumo, Wolnei; Allison, Kelly Costello; Stunkard, Albert; Hidalgo, Maria Paz

    2012-12-30

    This cross-sectional study examined the association between the morningness/eveningness dimension and eating patterns. The sample consists of 100 subjects who were screened at a nutrition clinic and was composed of 77% women; mean age was 39.5 (±11.7) years; and 66% were overweight. Significant bivariate correlations were found between the Morningness-Eveningness Questionnaire (MEQ) total score and the Binge Eating Scale (BES) and the Night Eating Questionnaire (NEQ). The NEQ and BES were also significantly correlated. Body mass index (BMI) was correlated with the NEQ and BES, but it was not a confounding variable as no associations were found between the MEQ and BMI. To control for potential multicollinearity effects among variables, we also used multivariate regression analysis in which the values of the correlation coefficients were adjusted. Only the BES remained statistically associated with the MEQ. In conclusion, these results suggest that the study of chronotype may be an important issue to be considered when characterizing disordered eating. This study serves as an impetus for examining circadian intake patterns in more detail between those with binge eating disorder (BED) and night eating syndrome (NES) to help discern these important nosological questions. PMID:22906954

  16. Pharmacological manipulations in animal models of anorexia and binge eating in relation to humans.

    Science.gov (United States)

    van Gestel, M A; Kostrzewa, E; Adan, R A H; Janhunen, S K

    2014-10-01

    Eating disorders, such as anorexia nervosa (AN), bulimia nervosa (BN) and binge eating disorders (BED), are described as abnormal eating habits that usually involve insufficient or excessive food intake. Animal models have been developed that provide insight into certain aspects of eating disorders. Several drugs have been found efficacious in these animal models and some of them have eventually proven useful in the treatment of eating disorders. This review will cover the role of monoaminergic neurotransmitters in eating disorders and their pharmacological manipulations in animal models and humans. Dopamine, 5-HT (serotonin) and noradrenaline in hypothalamic and striatal regions regulate food intake by affecting hunger and satiety and by affecting rewarding and motivational aspects of feeding. Reduced neurotransmission by dopamine, 5-HT and noradrenaline and compensatory changes, at least in dopamine D2 and 5-HT(2C/2A) receptors, have been related to the pathophysiology of AN in humans and animal models. Also, in disorders and animal models of BN and BED, monoaminergic neurotransmission is down-regulated but receptor level changes are different from those seen in AN. A hypofunctional dopamine system or overactive α2-adrenoceptors may contribute to an attenuated response to (palatable) food and result in hedonic binge eating. Evidence for the efficacy of monoaminergic treatments for AN is limited, while more support exists for the treatment of BN or BED with monoaminergic drugs.

  17. City of Bingöl in May 2003: Assessment of strong ground motion records

    Indian Academy of Sciences (India)

    U Çeken; G Beyhan; H H Selim

    2014-03-01

    The main shock of Bingöl earthquake ( = 6.4) recorded by six accelerometers in the area occurred at 03:27 local time on May 1, 2003. The largest acceleration value of north–south component was recorded as 545.5 cm/s2 at the nearest station which is 12 km away from the epicenter of earthquake. Especially, 0.15 s short period was observed when high spectral acceleration value occurred. An acceleration value greater than 50 gal was recorded at the BNG (Bingöl) station and structural damage occurred within 6.5 s was very important for the near source and strong ground motion seismology. The recorded peak acceleration values were greater than the estimated empirical acceleration values. However, the structural damage was not as high and widespread as expected. This occurrence was explained by considering the factors of earthquake source, frequency content, effective duration, effective acceleration value, local soil conditions, rupture direction and attenuation.

  18. Visual attentional bias for food in adolescents with binge-eating disorder.

    Science.gov (United States)

    Schmidt, Ricarda; Lüthold, Patrick; Kittel, Rebekka; Tetzlaff, Anne; Hilbert, Anja

    2016-09-01

    Evidence suggests that adults with binge-eating disorder (BED) are prone of having their attention interfered by food cues, and that food-related attentional biases are associated with calorie intake and eating disorder psychopathology. For adolescents with BED experimental evidence on attentional processing of food cues is lacking. Using eye-tracking and a visual search task, the present study examined visual orienting and disengagement processes of food in youth with BED. Eye-movement data and reaction times were recorded in 25 adolescents (12-20 years) with BED and 25 controls (CG) individually matched for sex, age, body mass index, and socio-economic status. During a free exploration paradigm, the BED group showed a greater gaze duration bias for food images than the CG. Groups did not differ in gaze direction biases. In a visual search task, the BED group showed a greater detection bias for food targets than the CG. Group differences were more pronounced for personally attractive than unattractive food images. Regarding clinical associations, only in the BED group the gaze duration bias for food was associated with increased hunger and lower body mass index, and the detection bias for food targets was associated with greater reward sensitivity. The study provided first evidence of an attentional bias to food in adolescents with BED. However, more research is needed for further specifying disengagement and orienting processes in adolescent BED, including overt and covert attention, and their prospective associations with binge-eating behaviors and associated psychopathology.

  19. Regional grey matter volume abnormalities in bulimia nervosa and binge-eating disorder.

    Science.gov (United States)

    Schäfer, Axel; Vaitl, Dieter; Schienle, Anne

    2010-04-01

    This study investigated whether bulimia nervosa (BN) and binge-eating disorder (BED) are associated with structural brain abnormalities. Both disorders share the main symptom binge-eating, but are considered differential diagnoses. We attempted to identify alterations in grey matter volume (GMV) that are present in both psychopathologies as well as disorder-specific GMV characteristics. Such information can help to improve neurobiological models of eating disorders and their classification. A total of 50 participants (patients suffering from BN (purge type), BED, and normal-weight controls) underwent structural MRI scanning. GMV for specific brain regions involved in food/reinforcement processing was analyzed by means of voxel-based morphometry. Both patient groups were characterized by greater volumes of the medial orbitofrontal cortex (OFC) compared to healthy controls. In BN patients, who had increased ventral striatum volumes, body mass index and purging severity were correlated with striatal grey matter volume. Altogether, our data implicate a crucial role of the medial OFC in the studied eating disorders. The structural abnormality might be associated with dysfunctions in food reward processing and/or self-regulation. The bulimia-specific volume enlargement of the ventral striatum is discussed in the framework of negative reinforcement through purging and associated weight regulation.

  20. CERN takes part in Earth Hour

    CERN Multimedia

    Anaïs Vernède

    2011-01-01

    From 8.30 to 9.30 p.m. on Saturday, 26 March 2011, the Globe of Science and Innovation will be plunged into darkness to mark CERN's participation in Earth Hour. A growing number of countries and cities across the planet are involved in this global initiative against climate change, which was launched by the WWF in 2007.   The lights on the Globe were switched off for the 2009 Earth Hour event. Along with individuals, companies and tourist attractions in thousands of towns and cities all over the world participating in the fourth annual Earth Hour event, CERN will turn off the lights of the Globe for 60 minutes at 8.30 p.m. on Saturday 26 March. CERN's participation in the initiative is one of several examples of its commitment to respect the environment and keep its ecological footprint to the minimum. A recent example under the green transport heading was the replacement of part of CERN's petrol vehicle fleet with cars running on natural gas with a view to reducing air pollution. Other examples...

  1. Resolving issues concerning Eskdalemuir geomagnetic hourly values

    Directory of Open Access Journals (Sweden)

    S. Macmillan

    2011-02-01

    Full Text Available The hourly values of the geomagnetic field from 1911 to 1931 derived from measurements made at Eskdalemuir observatory in the UK, and available online from the World Data Centre for Geomagnetism at http://www.wdc.bgs.ac.uk/, have now been corrected. Previously they were 2-point averaged and transformed from the original north, east and vertical down values in the tables in the observatory yearbooks. This paper documents the course of events from discovering the post-processing done to the data to the final resolution of the problem. As it was through the development of a new index, the Inter-Hour Variability index, that this post-processing came to light, we provide a revised series of this index for Eskdalemuir and compare it with that from another European observatory. Conclusions of studies concerning long-term magnetic field variability and inferred solar variability, whilst not necessarily consistent with one another, are not obviously invalidated by the incorrect hourly values from Eskdalemuir. This series of events illustrates the challenges that lie ahead in removing any remaining errors and inconsistencies in the data holdings of different World Data Centres.

  2. Salivary Hsp72 does not track exercise stress and caffeine-stimulated plasma Hsp72 responses in humans

    OpenAIRE

    Fortes, Matthew B.; Whitham, Martin

    2010-01-01

    Heat shock protein 72 (Hsp72) has been detected within saliva, and its presence may contribute to oral defence. It is currently unknown how physiological stress affects salivary Hsp72 or if salivary Hsp72 concentrations reflect plasma Hsp72 concentrations. We studied the effect of exercise upon salivary Hsp72 expression, and using caffeine administration, investigated the role of sympathetic stimulation upon salivary Hsp72 expression. Six healthy males performed two treadmill running exercise...

  3. Rank 72 high minimum norm lattices

    CERN Document Server

    Griess, Robert L

    2009-01-01

    Given a polarization of an even unimodular lattice and integer $k\\ge 1$, we define a family of unimodular lattices $L(M,N,k)$. Of special interest are certain $L(M,N,3)$ of rank 72. Their minimum norms lie in $\\{4, 6, 8\\}$. Norms 4 and 6 do occur. Consequently, 6 becomes the highest known minimum norm for rank 72 even unimodular lattices. We discuss how norm 8 might occur for such a $L(M,N,3)$. We note a few $L(M,N,k)$ in dimensions 96, 120 and 128 with moderately high minimum norms.

  4. Dietary Restraint Partially Mediates the Relationship between Impulsivity and Binge Eating Only in Lean Individuals: The Importance of Accounting for Body Mass in Studies of Restraint

    Science.gov (United States)

    Coffino, Jaime A.; Orloff, Natalia C.; Hormes, Julia M.

    2016-01-01

    Binge eating is characteristic of eating and weight-related disorders such as binge eating disorder, bulimia nervosa, and obesity. In light of data suggest impulsivity is associated with overeating specifically in restrained eaters, this study sought to elucidate the exact nature of the associations between these variables, hypothesizing that the relationship between impulsivity and binge eating is mediated by restrained eating. We further hypothesized that the role of dietary restraint as a mediator would be moderated by body mass index (BMI). Study participants (n = 506, 50.6% female) were categorized based on self-reported BMI as under- and normal-weight (BMI Emotion Regulation Scale, and the Binge Eating Scale. Findings provide initial evidence for the hypothesized moderated mediation model, with dietary restraint partially mediating the relationship between impulsivity and binge eating severity only in lean respondents. In respondents with overweight or obesity, impulsivity was significantly correlated with binge eating severity, but not with dietary restraint. Findings inform our conceptualization of dietary restraint as a possible risk factor for binge eating and highlight the importance of accounting for body mass in research on the impact of dietary restraint on eating behaviors. PMID:27757092

  5. Binge eating, purging and non-purging compensatory behaviours decrease from adolescence to adulthood: A population-based, longitudinal study

    OpenAIRE

    Abebe Dawit; Lien Lars; Torgersen Leila; von Soest Tilmann

    2012-01-01

    Background Subclinical forms of eating disorders (ED) are highly prevalent, but relatively little is known about age trends, gender differences and distinctions among symptoms. This study investigates age trends and gender difference in binge eating, purging and non-purging compensatory behaviours (CB) and the relationship of such behaviours to psychosocial problems. Methods Data from the national rep...

  6. University Binge Drinking Patterns and Changes in Patterns of Alcohol Consumption among Chinese Undergraduates in a Hong Kong University

    Science.gov (United States)

    Kim, Jean H.; Chan, Karli W. C.; Chow, Julie K. W.; Fung, K. P.; Fong, Ben Y. F.; Cheuk, Ka Kin; Griffiths, Sian M.

    2009-01-01

    Objective: To examine patterns of binge drinking and changes in drinking patterns among Chinese university students. Participants and Methods: Responses to an anonymous questionnaire were compared between a random sample of 411 second year Chinese undergraduate students in 2006 and 2,630 first year students from the previous year. Students…

  7. The Influence of a Web-Based Course on Alcohol Consumption and Binge Drinking Behavior among First Year Students

    Science.gov (United States)

    Robinson, Lillian D.

    2011-01-01

    Underage drinking and risky alcohol consumption are issues that have garnered a great deal of national and local attention and subsequently many prevention efforts. The consumption of alcohol and binge drinking by minors jeopardizes not only their quality of life and academic success, but also places the individual and others at an increased risk…

  8. Adenosinergic regulation of binge-like ethanol drinking and associated locomotor effects in male C57BL/6J mice.

    Science.gov (United States)

    Fritz, Brandon M; Boehm, Stephen L

    2015-08-01

    We recently observed that the addition of caffeine (a nonselective adenosine receptor antagonist) to a 20% ethanol solution significantly altered the intoxication profile of male C57BL/6J (B6) mice induced by voluntary binge-like consumption in the 'Drinking-in-the-Dark' (DID) paradigm. In the current study, the roles of A1 and A2A adenosine receptor subtypes, specifically, in binge-like ethanol consumption and associated locomotor effects were explored. Adult male B6 mice (PND 60-70) were allowed to consume 20% ethanol (v/v) or 2% sucrose (w/v) for 6days via DID. On day 7, mice received a systemic administration (i.p.) of the A1 antagonist DPCPX (1, 3, 6mg/kg), the A2A antagonist MSX-3 (1, 2, 4mg/kg), or vehicle immediately prior to fluid access in DID. Antagonism of the A1 receptor via DPCPX was found to dose-dependently decrease binge-like ethanol intake and associated blood ethanol concentrations (p'sconsumption, however, MSX-3 elicited robust locomotor stimulation in mice consuming either solution (p's<0.05). Together, these findings suggest unique roles for the A1 and A2A adenosine receptor subtypes in binge-like ethanol intake and its associated locomotor effects. PMID:26033424

  9. The prevalence of DSM-IV personality pathology among individuals with bulimia nervosa, binge eating disorder and obesity

    NARCIS (Netherlands)

    De Jonge, PV; Van Furth, EF; Lacey, JH; Waller, G

    2003-01-01

    Background. There are numerous reports of personality disorder pathology in different eating disorders. However, few studies have directly compared personality pathology in bulimia nervosa, binge eating disorder and obesity. The present study examines group differences in DSM-IV personality patholog

  10. The Prevalence of Binge Eating Disorder and Its Relationship to Work and Classroom Productivity and Activity Impairment

    Science.gov (United States)

    Filipova, Anna A.; Stoffel, Cheri L.

    2016-01-01

    Objective: The study aimed to determine the prevalence of binge eating disorder on university campus, its associations with health risk factors, and its associations with work and classroom productivity and activity impairment, adjusted for health risk factors. Participants: The study was conducted at a public midwestern university in the United…

  11. Predictors and Moderators of Response to Cognitive Behavioral Therapy and Medication for the Treatment of Binge Eating Disorder

    Science.gov (United States)

    Grilo, Carlos M.; Masheb, Robin M.; Crosby, Ross D.

    2012-01-01

    Objective: To examine predictors and moderators of response to cognitive behavioral therapy (CBT) and medication treatments for binge-eating disorder (BED). Method: 108 BED patients in a randomized double-blind placebo-controlled trial testing CBT and fluoxetine treatments were assessed prior, throughout, and posttreatment. Demographic factors,…

  12. Cultural Adaptation of a Cognitive Behavior Therapy Guided Self-Help Program for Mexican American Women with Binge Eating Disorders

    Science.gov (United States)

    Shea, Munyi; Cachelin, Fary; Uribe, Luz; Striegel, Ruth H.; Thompson, Douglas; Wilson, G. Terence

    2012-01-01

    Data on the compatibility of evidence-based treatment in ethnic minority groups are limited. This study utilized focus group interviews to elicit Mexican American women's (N = 12) feedback on a cognitive behavior therapy guided self-help program for binge eating disorders. Findings revealed 6 themes to be considered during the cultural adaptation…

  13. Psychiatric Disorders Associated with the Onset and Persistence of Bulimia Nervosa and Binge Eating Disorder during Adolescence.

    Science.gov (United States)

    Zaider, Talia I.; Johnson, Jeffrey G.; Cockell, Sarah J.

    2002-01-01

    Conducted a prospective longitudinal study to investigate whether anxiety, depressive, personality, or substance abuse disorders increase risk for onset of bulimia nervosa (BN) or binge eating disorder (BED) during adolescence. Findings for 201 adolescents suggest that adolescents with chronic depressive symptoms may be at elevated risk for the…

  14. Predictors and Moderators of Response to Cognitive Behavioral Therapy and Medication for the Treatment of Binge Eating Disordspan>er

    Science.gov (United States)

    Grilo, Carlos M.; Masheb, Robin M.; Crosby, Ross D.

    2012-01-01

    Objective: To examine predictors and moderators of response to cognitive behavioral therapy (CBT) and medication treatments for binge-eating disorder (BED). Method: 108 BED patients in a randomized double-blind placebo-controlled trial testing CBT and fluoxetine treatments were assessed prior, throughout, and posttreatment. Demographic factors,…

  15. Health services use in women with a history of bulimia nervosa or binge eating disorder

    NARCIS (Netherlands)

    Striegel-Moore, RH; Dohm, FA; Kraemer, HC; Schreiber, GB; Crawford, PB; Daniels, [No Value

    2005-01-01

    Objective: The current study examined health services use during the past 12 months in a sample of young women with a history of an adolescent eating disorder (bulimia nervosa [BN] or binge eating disorder [BED]). Method: A community sample of 1,582 young women (mean age = 21.5 years) was classified

  16. Incidence and Weight Trajectories of Binge Eating Disorder among Young Women in the Community

    NARCIS (Netherlands)

    Mustelin, Linda; Raevuori, Anu; Hoek, Hans Wijbrand; Kaprio, Jaakko; Keski-Rahkonen, Anna

    2015-01-01

    Objective: To assess the population prevalence and incidence of binge eating disorder (BED) among young women. Method: In a nationwide longitudinal study of Finnish twins born 1975-1979, the women participated in five surveys from age 16 until their mid-thirties. At Wave 4 (mean age 24 years), the w

  17. Adenosinergic regulation of binge-like ethanol drinking and associated locomotor effects in male C57BL/6J mice

    Science.gov (United States)

    Fritz, Brandon M; Boehm, Stephen L

    2015-01-01

    We recently observed that the addition of caffeine (a nonselective adenosine receptor antagonist) to a 20% ethanol solution significantly altered the intoxication profile of male C57BL/6J (B6) mice induced by voluntary binge-like consumption in the ‘Drinking-in-the-Dark’ (DID) paradigm. In the current study, the roles of A1 and A2A adenosine receptor subtypes, specifically, in binge-like ethanol consumption and associated locomotor effects were explored. Adult male B6 mice (PND 60-70) were allowed to consume 20% ethanol (v/v) or 2% sucrose (w/v) for 6 days via DID. On day 7, mice received a systemic administration (i.p.) of the A1 antagonist DPCPX (1, 3, 6 mg/kg), the A2A antagonist MSX-3 (1, 2, 4 mg/kg), or vehicle immediately prior to fluid access in DID. Antagonism of the A1 receptor via DPCPX was found to dose-dependently decrease binge-like ethanol intake and associated blood ethanol concentrations (p’s < 0.05), although no effect was observed on sucrose intake. Antagonism of A2A had no effect on ethanol or sucrose consumption, however, MSX-3 elicited robust locomotor stimulation in mice consuming either solution (p’s < 0.05). Together, these findings suggest unique roles for the A1 and A2A adenosine receptor subtypes in binge-like ethanol intake and its associated locomotor effects. PMID:26033424

  18. Components of Negative Affect as Moderators of the Relationship between Early Drinking Onset and Binge-Drinking Behavior

    Science.gov (United States)

    McNamara, Robert S.; Swaim, Randall C.; Rosen, Lee A.

    2010-01-01

    This study examines the moderating effects of negative affect on the relationship between early drinking onset and binge-drinking behavior. Six hundred and thirty-five eleventh- and twelfth-grade students completed the American Drug and Alcohol Survey and reported on a variety of measures, including items assessing anxiety, anger, depression, age…

  19. Attachment Styles and Changes among Women Members of Overeaters Anonymous Who Have Recovered from Binge-Eating Disorder

    Science.gov (United States)

    Hertz, Pnina; Addad, Moshe; Ronel, Natti

    2012-01-01

    In Overeaters Anonymous (OA), the 12-step self-help program for compulsive overeaters, binge eating is regarded as a physical, spiritual, and emotional disorder. Consequently, the program proposes recovery through the adoption of a lifestyle that leads to physical, spiritual, and emotional well-being. A qualitative phenomenological study that…

  20. 32 CFR 516.72 - Procedures.

    Science.gov (United States)

    2010-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Cooperation With the Office of Special Counsel § 516.72 Procedures. (a) Witnesses and... OSC investigation, the OSC files a complaint against DA or a DA employee, release of records and...

  1. 10 CFR 72.10 - Employee protection.

    Science.gov (United States)

    2010-01-01

    ... Form 3, “Notice to Employees,” referenced in 10 CFR 19.11(c). This form must be posted at locations..., HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.10... the index found on the home page. (f) No agreement affecting the compensation, terms, conditions,...

  2. 9 CFR 145.72 - Participation.

    Science.gov (United States)

    2010-01-01

    ... LIVESTOCK IMPROVEMENT NATIONAL POULTRY IMPROVEMENT PLAN FOR BREEDING POULTRY Special Provisions for Primary Egg-Type Chicken Breeding Flocks and Products § 145.72 Participation. Participating flocks of primary egg-type chickens, and the eggs and chicks produced from them, shall comply with the...

  3. 39 CFR 3020.72 - Supporting justification.

    Science.gov (United States)

    2010-07-01

    ... nature of enterprises in the private sector engaged in the delivery of the product; (g) Provide any... Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PRODUCT LISTS Proposal of the Commission To Modify the Product Lists Described Within the Mail Classification Schedule § 3020.72 Supporting...

  4. 24 CFR 7.2 - Definitions.

    Science.gov (United States)

    2010-04-01

    ..., Color Religion, Sex, National Origin, Age, Disability or Reprisal General Provisions § 7.2 Definitions... at 29 CFR part 1614 and this part. Diversity Program Manager means the designee appointed by the... designated as the Director of EEO in this part. Disability means the same as the term “handicap” under...

  5. 21 CFR 201.72 - Potassium labeling.

    Science.gov (United States)

    2010-04-01

    ...-restricted diet”. The warnings in §§ 201.64(c), 201.70(c), 201.71(c), and 201.72(c) may be combined, if...-restricted diet. 1 See § 201.66(b)(4) of this chapter for definition of bullet symbol. (d) Any...

  6. Ethylene Oxide: Acute Four-Hour and One-Hour Inhalation Toxicity Testing in Rats

    Directory of Open Access Journals (Sweden)

    William M. Snellings

    2011-01-01

    Full Text Available Ethylene oxide was tested on groups of rats for either 4-hour or 1-hour inhalation exposure, followed by 14 days of observation. Groups of five Sprague-Dawley rats/sex were exposed, and clinical signs and mortality were recorded. Clinical signs noted included irregular breathing, absence of certain reflexes, and tremors. Rats that died had moderate to severe pulmonary congestion. The calculated LC50 values, reported as ppm by volume (with 95% confidence limits, were as follows. 4-hour LC50 values were 1972 (1887 to 2061 ppm for males; 1537 (1391 to 1698 ppm for females; 1741 (1655 to 1831 ppm for the combined sexes. The 1-hour LC50 values were 5748 (5276 to 6262 ppm for males; 4439 (4034 to 4884 ppm for females; 5029 (4634 to 5459 ppm for the combined sexes.

  7. Gate A: changes to opening hours

    CERN Multimedia

    2015-01-01

    Due to maintenance work, the opening hours of Gate A (near Reception) will be modified between Monday, 13 and Friday, 17 April 2015.   During this period, the gate will be open to vehicles between 7 a.m. and 9.30 a.m., then between 4.30 p.m. and 7 p.m. It will be completely closed to traffic between 9.30 a.m. and 4.30 p.m. Pedestrians and cyclists may continue to use the gate. We apologise for any inconvenience and thank you for your understanding.

  8. New opening hours of the gates

    CERN Multimedia

    GS Department

    2009-01-01

    Please note the new opening hours of the gates as well as the intersites tunnel from the 19 May 2009: GATE A 7h - 19h GATE B 24h/24 GATE C 7h - 9h\t17h - 19h GATE D 8h - 12h\t13h - 16h GATE E 7h - 9h\t17h - 19h Prévessin 24h/24 The intersites tunnel will be opened from 7h30 to 18h non stop. GS-SEM Group Infrastructure and General Services Department

  9. Temporary new opening hours for Gate C

    CERN Multimedia

    GS Department

    2010-01-01

    Please note the new temporary opening hours for the gate C as from 22 September 2010 until 29 October 2010 (working days): Morning: between 7:00 a.m. and 9:00 a.m. Lunch: between 12:00 and 2:00 p.m. Evening: between 5:00 pm and 7:00 p.m. Traffic flow will be permitted in both directions during this period. Please minimize your speed accordingly and respect all road signs. GS-SEM Group General Infrastructure Services Department

  10. Work Hours and Absenteeism Among Police Officers

    OpenAIRE

    Fekedulegn, Desta; Burchfiel, Cecil M.; Hartley, Tara A.; Baughman, Penelope; Charles, Luenda E.; Andrew, Michael E.; Violanti, John M.

    2013-01-01

    In this study, the cross-sectional association of paid work hours with episodes of work absence was examined in a cohort of police officers. Study subjects were participants from the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) study examined between 2004 and 2009. Among 395 study participants with complete data, day-by-day work history records during the one-year period prior to date of examination were used to determine episodes of one-day and three day work absence. The Nega...

  11. WordPress 24-hour trainer

    CERN Document Server

    Plumley, George

    2015-01-01

    Create and expand feature-rich sites with no programming experience Ready to build, maintain, and expand your web site with WordPress but have no prior programming experience? WordPress 24-Hour Trainer, 3rd Edition is your book-and-video learning solution that walks you step-by-step through all the important features you will need to know. Lessons range from focused, practical everyday tasks to more advanced, creative features. Learn from an industry professional how to enter content, create pages, manage menus, utilize plug-ins, connect to social media, create membership and e-commerce site

  12. Complex motivated behaviors for natural rewards following a binge-like regimen of morphine administration: mixed phenotypes of anhedonia and craving after short-term withdrawal

    Directory of Open Access Journals (Sweden)

    Yunjing eBai

    2014-02-01

    Full Text Available The anhedonia-like behaviors following about one-week withdrawal from morphine were examined in the present study. Male rats were pretreated with either a binge-like morphine paradigm or daily saline injection for 5 days. Three types of natural reward were used, food reward (2.5%, 4%, 15%, 30%, 40% and 60% sucrose solutions, social reward (male rat and sexual reward (estrous female rat. For each type of natural stimulus, consummatory behavior and motivational behaviors under varied testing conditions were investigated. The results showed that the morphine-treated rats significantly reduced their consumption of 2.5% sucrose solution during the 1-hour consumption testing and their operant responding for 15%, 30% and 40% sucrose solutions under a fixed ratio 1 (FR1 schedule. However, performance under a progressive ratio (PR schedule increased in morphine-treated rats reinforced with 60% sucrose solution, but not in those reinforced with sucrose concentrations lower than 60%. Pretreatment with morphine significantly decreased the male rats’ ejaculation frequency during the 1-hour copulation testing, and impaired the maintenance of appetitive motivations to sexual and social stimuli under a free-approach condition. Moreover, the morphine-treated rats demonstrated a diminished motivation to approach social stimulus in the effort-based appetitive behavior test but showed a remarkable increase in motivation to approach sexual stimulus in the risky appetitive behavior test. These results demonstrated some complex motivated behaviors following about one week of morphine withdrawal: (1 The anhedonia-like behavior was consistently found in animals withdrawn from morphine. However, for a given reward, there was often a dissociation of the consummatory behaviors from the motivational behaviors, and whether the consummatory or the motivational anhedonia-like behaviors could be discovered heavily depended on the type and magnitude of the reward and the type

  13. Computed tomography assessment of peripubertal craniofacial morphology in a sheep model of binge alcohol drinking in the first trimester.

    Science.gov (United States)

    Birch, Sharla M; Lenox, Mark W; Kornegay, Joe N; Shen, Li; Ai, Huisi; Ren, Xiaowei; Goodlett, Charles R; Cudd, Tim A; Washburn, Shannon E

    2015-11-01

    Identification of facial dysmorphology is essential for the diagnosis of fetal alcohol syndrome (FAS); however, most children with fetal alcohol spectrum disorders (FASD) do not meet the dysmorphology criterion. Additional objective indicators are needed to help identify the broader spectrum of children affected by prenatal alcohol exposure. Computed tomography (CT) was used in a sheep model of prenatal binge alcohol exposure to test the hypothesis that quantitative measures of craniofacial bone volumes and linear distances could identify alcohol-exposed lambs. Pregnant sheep were randomly assigned to four groups: heavy binge alcohol, 2.5 g/kg/day (HBA); binge alcohol, 1.75 g/kg/day (BA); saline control (SC); and normal control (NC). Intravenous alcohol (BA; HBA) or saline (SC) infusions were given three consecutive days per week from gestation day 4-41, and a CT scan was performed on postnatal day 182. The volumes of eight skull bones, cranial circumference, and 19 linear measures of the face and skull were compared among treatment groups. Lambs from both alcohol groups showed significant reduction in seven of the eight skull bones and total skull bone volume, as well as cranial circumference. Alcohol exposure also decreased four of the 19 craniofacial measures. Discriminant analysis showed that alcohol-exposed and control lambs could be classified with high accuracy based on total skull bone volume, frontal, parietal, or mandibular bone volumes, cranial circumference, or interorbital distance. Total skull volume was significantly more sensitive than cranial circumference in identifying the alcohol-exposed lambs when alcohol-exposed lambs were classified using the typical FAS diagnostic cutoff of ≤10th percentile. This first demonstration of the usefulness of CT-derived craniofacial measures in a sheep model of FASD following binge-like alcohol exposure during the first trimester suggests that volumetric measurement of cranial bones may be a novel biomarker

  14. Evaluating a selective prevention programme for binge drinking among young adolescents: study protocol of a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Wiers Reinout

    2011-02-01

    Full Text Available Abstract Background In comparison to other Europe countries, Dutch adolescents are at the top in drinking frequency and binge drinking. A total of 75% of the Dutch 12 to 16 year olds who drink alcohol also engage in binge drinking. A prevention programme called Preventure was developed in Canada to prevent adolescents from binge drinking. This article describes a study that aims to assess the effects of this selective school-based prevention programme in the Netherlands. Methods A randomized controlled trial is being conducted among 13 to 15-year-old adolescents in secondary schools. Schools were randomly assigned to the intervention and control conditions. The intervention condition consisted of two 90 minute group sessions, carried out at the participants' schools and provided by a qualified counsellor and a co-facilitator. The intervention targeted young adolescents who demonstrated personality risk for alcohol abuse. The group sessions were adapted to four personality profiles. The control condition received no further intervention above the standard substance use education sessions provided in the Dutch national curriculum. The primary outcomes will be the percentage reduction in binge drinking, weekly drinking and drinking-related problems after three specified time periods. A screening survey collected data by means of an Internet questionnaire. Students have completed, or will complete, a post-treatment survey after 2, 6, and 12 months, also by means of an online questionnaire. Discussion This study protocol presents the design and current implementation of a randomized controlled trial to evaluate the effectiveness of a selective alcohol prevention programme. We expect that a significantly lower number of adolescents will binge drink, drink weekly, and have drinking-related problems in the intervention condition compared to the control condition, as a result of this intervention. Trial registration This trial is registered in the Dutch

  15. Binge Drinking among Men Who Have Sex with Men and Transgender Women in San Salvador: Correlates and Sexual Health Implications.

    Science.gov (United States)

    Peacock, Erin; Andrinopoulos, Katherine; Hembling, John

    2015-08-01

    High rates of heavy alcohol use among men who have sex with men (MSM) and transgender women (TW) have been linked to increased vulnerability for HIV and poor mental health. While theories explaining elevated drinking levels among sexual minorities have been forwarded, few investigations have assessed the potential pathways using empirical data, particularly with an explicit focus on self-stigma and among MSM and TW in low- and middle-income countries. This study examined the relationship between stigma-related stress (specifically, self-stigma and concealment of one's sexual orientation) and binge drinking in a sample of MSM and TW (n = 670) in San Salvador, El Salvador, recruited using respondent-driven sampling. Levels of alcohol consumption among participants were high: only 39 % of the sample did not drink alcohol or did not binge drink, while 34 % engaged in binge drinking at least weekly. Among MSM, high self-stigma was associated with binge drinking at least weekly (adjusted relative risk ratio (aRRR) = 2.1, p risk behavior and was actually associated with increased intention to test for HIV in the next 12 months (aOR = 2.8, p risk behavior (and may even be associated with increased intention to test for HIV in the next 12 months) lends further support to the suggestion that these individuals with healthy concepts of the self (as indicated by high levels of disclosure and low levels of risky sexual behavior) may engage in binge drinking because of the influence of the social environment. Further research is needed to establish the pathways linking stigma-related stress to heavy alcohol use so that points of intervention can be identified. PMID:25591660

  16. Production Facility Prototype Blower 1000 Hour Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Woloshun, Keith Albert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dale, Gregory E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Frank Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dalmas, Dale Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-18

    The roots blower in use at ANL for in-beam experiments and also at LANL for flow tests was sized for 12 mm diameter disks and significantly less beam heating. Currently, the disks are 29 mm in diameter, with a 12 mm FWHM Gaussian beam spot at 42 MeV and 2.86 μA on each side of the target, 5.72 μA total. The target design itself is reported elsewhere. With the increased beam heating, the helium flow requirement increased so that a larger blower was need for a mass flow rate of 400 g/s at 2.76 MPa (400 psig). An Aerzen GM 12.4 blower was selected, and is now installed at the LANL facility for target and component flow testing. Two extended test of >1000 hr operation have been completed. Those results and discussion thereof are reported herein. Also included in Appendix A is the detailed description of the blower and its installation, while Appendix B documents the pressure vessel design analysis. The blower has been operated for 1000 hours as a preliminary investigation of long term performance, operation and possible maintenance issues. The blower performed well, with no significant change in blower head or mass flow rate developed under the operating conditions. Upon inspection, some oil had leaked out of the shaft seal of the blower. The shaft seal and bearing race have been replaced. Test results and conclusions are in Appendix B.

  17. Body image disturbance in binge eating disorder: a comparison of obese patients with and without binge eating disorder regarding the cognitive, behavioral and perceptual component of body image.

    Science.gov (United States)

    Lewer, Merle; Nasrawi, Nadia; Schroeder, Dorothea; Vocks, Silja

    2016-03-01

    Whereas the manifestation of body image disturbance in binge eating disorder (BED) has been intensively investigated concerning the cognitive-affective component, with regard to the behavioral and the perceptual components of body image disturbance in BED, research is limited and results are inconsistent. Therefore, the present study assessed body image disturbance in BED with respect to the different components of body image in a sample of obese females (n = 31) with BED compared to obese females without an eating disorder (n = 28). The Eating Disorder Inventory-2, the Eating Disorder Examination-Questionnaire, the Body Image Avoidance Questionnaire and the Body Checking Questionnaire as well as a Digital Photo Distortion Technique based on a picture of each participant taken under standardized conditions were employed. Using two-sample t tests, we found that the participants with BED displayed significantly greater impairments concerning the cognitive-affective component of body image than the control group. Concerning the behavioral component, participants with BED reported more body checking and avoidance behavior than the controls, but group differences failed to reach significance after the Bonferroni corrections. Regarding the perceptual component, a significant group difference was found for the perceived "ideal" figure, with the individuals suffering from BED displaying a greater wish for a slimmer ideal figure than the control group. These results support the assumption that body image disturbance is a relevant factor in BED, similar to other eating disorders. PMID:26178486

  18. Body image disturbance in binge eating disorder: a comparison of obese patients with and without binge eating disorder regarding the cognitive, behavioral and perceptual component of body image.

    Science.gov (United States)

    Lewer, Merle; Nasrawi, Nadia; Schroeder, Dorothea; Vocks, Silja

    2016-03-01

    Whereas the manifestation of body image disturbance in binge eating disorder (BED) has been intensively investigated concerning the cognitive-affective component, with regard to the behavioral and the perceptual components of body image disturbance in BED, research is limited and results are inconsistent. Therefore, the present study assessed body image disturbance in BED with respect to the different components of body image in a sample of obese females (n = 31) with BED compared to obese females without an eating disorder (n = 28). The Eating Disorder Inventory-2, the Eating Disorder Examination-Questionnaire, the Body Image Avoidance Questionnaire and the Body Checking Questionnaire as well as a Digital Photo Distortion Technique based on a picture of each participant taken under standardized conditions were employed. Using two-sample t tests, we found that the participants with BED displayed significantly greater impairments concerning the cognitive-affective component of body image than the control group. Concerning the behavioral component, participants with BED reported more body checking and avoidance behavior than the controls, but group differences failed to reach significance after the Bonferroni corrections. Regarding the perceptual component, a significant group difference was found for the perceived "ideal" figure, with the individuals suffering from BED displaying a greater wish for a slimmer ideal figure than the control group. These results support the assumption that body image disturbance is a relevant factor in BED, similar to other eating disorders.

  19. Make a movie in 48 hours

    CERN Multimedia

    Brokk Toggerson

    2011-01-01

    This year, the 48-hour film project (48hfp) returns to Geneva after a one-year hiatus. Organized by Neal Hartman and the CERN film-making club, Open Your Eyes Films, the 48hfp challenges teams of film-makers to write, shoot, soundtrack and edit a 4 to 7 minute film in 48 hours from 4 to 6 November.   At the start of the festival, contestants picked their film genre from a hat. The films will be screened on 8 and 9 November, with the awards presentation on the 9th. The winner will receive a trip to the US to compete in the international version of the competition. “There are so many short films being made now," says Hartman, “I think, however, that the 48hfp allows a critical creative mass to form. The result is that these 20 teams make 20 better films than if each participant were making their own." Each team draws a genre from a hat and is given a character, a prop and a line of dialogue that must appear in their film. The genres run the gamut from &am...

  20. Development and quality assessment of ‘Bei Bing Hong ’sparkling wine%山葡萄‘北冰红’起泡葡萄酒研发与评价

    Institute of Scientific and Technical Information of China (English)

    王华; 张莉; 丁吉星; 李华; 段琪; 崔长伟

    2015-01-01

    Sparkling wine was developed using vitis amurensis ‘ Bei Bing Hong’ as raw material through new technology.Quality assessment system for ‘ Bei Bing Hong’ sparkling wine was established through four aspects including the basic physicochemical index,phenolic compounds,aroma compounds and sensory characteristics.Basic physiochemieal composition of the sparkling wine met the requirements of National Standard.The total phenol,tannis and total flavonoids were higher,while total anthocyanins and flavanol were lower.17 kinds mono-phenolics were detected including 6 flavonoids (17.70 mg/L,32.47%) and 11 non-flanvonoids (36.81 mg/L,67.53%).By SBSE-GC-MS analysis,72 aroma compounds were identified in the sparkling wines,and the aroma profile was mainly contributed by esters,carbonyls,alcohols,and terpenes.Typical aroma characters of Bei Bing Hong sparkling wine were fruity aroma such as apple,apricot,pear,strawberry,cherry and sweet melon.The results showed that the sparkling wine had slight structure,potation to age,high antioxidant activity,and intense flavors,which indicated that the quality of sparkling wine made from ‘ Bei Bing Hong’ was good.%以山葡萄‘北冰红’为原料,采用新工艺研发了山葡萄起泡酒,并从基本理化指标、酚类物质、特征香气、感官分析4个方面构建了抗寒酿酒葡萄新品种‘北冰红’起泡葡萄酒质量评价体系.结果表明:北冰红起泡葡萄酒各项基本理化指标均符合国家标准要求;总酚、单宁和总类黄酮含量较高,分别为868.02、1 340.76和828.38 mg/L;总花色苷和总黄烷-3-醇含量较低,分别为9.05 mg/L和36.03 mg/L.‘北冰红’起泡酒中共检测出17种单体酚:其中类黄酮类单体6种,总量为17.71 mg/L,占单体酚总量的32.47%;非类黄酮类11种,总量为36.81 mg/L,占总量的67.53%.通过SBSE-GC/MS分析,‘北冰红’起泡酒中检测到72种香气物质,对起泡酒香气影响较大的是酯类、醛酮类、醇

  1. Binge Drinking

    Science.gov (United States)

    ... issues, so an alternative could be a trusted friend or older sibling who is easy to talk to. Drinking too much can be the result of social pressures, and sometimes it helps to know there ... for help. A supportive friend or adult could help you to avoid pressure ...

  2. Binge Drinking

    Science.gov (United States)

    ... PDF file Microsoft PowerPoint file Microsoft Word file Microsoft Excel ... Centers for Disease Control and Prevention Page maintained by: Office of the Associate Director for Communication, Division of ...

  3. STS-72 Liftoff viewed from scrubs

    Science.gov (United States)

    1996-01-01

    The Space Shuttle Endeavour lights up the night sky as it thunders aloft from Launch Pad 39B. Liftoff of Mission STS- 72 occurred at 4:41:00.072 am EST, January 11, kicking off the 1996 Shuttle launch schedule. On board Endeavour are a crew of six: Commander Brian Duffy; Pilot Brent W. Jett; and Mission Specialists Dr. Daniel T. Barry, Leroy Chiao, Winston E. Scott, and Koichi Wakata, who represents the National Space Development Agency (NASDA) of Japan. During their planned nine-day mission, the crew will retrieve the Japanese Space Flyer Unit (SFU), deploy and later retrieve the Office of Aeronautics and Space Technology-Flyer (OAST- Flyer), and conduct two extravehicular activities (EVAs). STS-72 is the 74th Shuttle mission and the 10th flight of the orbiter Endeavour.

  4. ENDOSCOPIC SEPTOPLASTY: REVIEW OF 72 CASES

    Directory of Open Access Journals (Sweden)

    Gurivi Reddy Siva Prasad

    2016-07-01

    Full Text Available OBJECTIVES To review 72 patients who underwent endoscopic septoplasty over a period of three years. STUDY DESIGN Prospective Study. RESULTS Out of 72 cases, 53 cases were performed alone as a primary procedure, 19 cases were performed in conjunction with endoscopic sinus surgery, 39 cases were presented with spur, 24 cases with broadly-based deviations, 9 were traumatic deviations. There were 46 males and 26 were female. CONCLUSION Endoscopic septoplasty offers an alternative to conventional septoplasty with superior visualisation and minimal trauma. Endoscopic septoplasty helps in better correction of complex deformities and in correcting high deviations. It facilitates realignment by limited and precise resection of the deviated area. It effectively relieves headache caused by contact areas in nasal cavity especially in cases of septal spur.

  5. Binge Drinking in youth: evaluation of a test based in the theory of planned behavior

    Directory of Open Access Journals (Sweden)

    Luque, Leticia E.

    2014-08-01

    Full Text Available We present the first stage of the construction of a questionnaire that explores cognitive determinants of binge drinking in young subjetcs (16-25 years old, from Cordoba-Argentina. The test – with hundred ten items – including all cognitive determinants, considered by the Theory of Planning Behavior, proposed by I.Azjen. Exploratory factor analyzes indicate that the intensity scales beliefs have two components; the importance of beliefs items were grouped according to such components. Internal consistency coefficient’s (Cronbach's Alpha range between .61 and .94. The correlation element-total of all items is greater than .30. We suggest the creation of new items associated with perceived control and studies related to subjective norm and normative beliefs.

  6. Ringkøbing-Skjern Energy Atlas for municipal energy planning

    DEFF Research Database (Denmark)

    Petrovic, Stefan; Karlsson, Kenneth Bernard

    2015-01-01

    resources, societal and other energy data have been geographically referenced and combined with the tools built in ArcGIS software. The data have been collected from various sources: freely accessible public databases, the municipality, district heating and electricity companies, Danish transmission system......Ringkøbing-Skjern is Denmark's largest municipality, located in the west part of Central Denmark Region. Its medium-term goal is to achieve 100 % self-sufficiency in renewable energy supply by 2020. To achieve this ambitious goal, future courses of action have been outlined in the municipality......'s energy strategy "Energy2020" and divided into five groups: increasing production from wind, bioenergy and other renewable energy sources, reducing heat demand in buildings and converting transportation sector to renewable energy. The analysis of technical, economic and environmental impacts...

  7. Cognitive interference and a food-related memory bias in binge eating disorder.

    Science.gov (United States)

    Svaldi, Jennifer; Schmitz, Florian; Trentowska, Monika; Tuschen-Caffier, Brunna; Berking, Matthias; Naumann, Eva

    2014-01-01

    The present study was concerned with cognitive interference and a specific memory bias for eating-related stimuli in binge eating disorder (BED). Further objectives were to find out under which circumstances such effects would occur, and whether they are related with each other and with reported severity of BED symptoms. A group of women diagnosed with BED and a matched sample of overweight controls completed two paradigms, an n-back task with lures and a recent-probes task. The BED group generally experienced more interference in the n-back task. Additionally, they revealed selectively increased interference for food items in the recent-probes task. Findings can be reconciled with the view that control functions are generally impaired in BED, and that there is an additional bias for eating-related stimuli, both of which were related with reported severity of BED symptoms.

  8. Prolonged withdrawal following cocaine self-administration increases resistance to punishment in a cocaine binge

    Science.gov (United States)

    Gancarz-Kausch, Amy M.; Adank, Danielle N.; Dietz, David M.

    2014-01-01

    Drug addiction is characterized by compulsive drug-taking behaviors and a high propensity to relapse following drug cessation. Drug craving and seeking can increase during a period of abstinence, but this phenomenon is not observed in drug-induced reinstatement models. To investigate the effect of withdrawal on cocaine relapse, rats were exposed to extended-access cocaine self-administration and subjected to either 1 or 30 d of withdrawal. When tested during 12 h unlimited access to cocaine (binge), the duration of the withdrawal did not influence cocaine intake. However, using a histamine punishment procedure that greatly suppresses drug-taking behavior, we demonstrate that longer periods of abstinence from cocaine induce a greater persistence in responding for drug in the face of negative consequences. PMID:25363133

  9. Average use of Alcohol and Binge Drinking in Pregnancy: Neuropsychological Effects at Age 5

    DEFF Research Database (Denmark)

    Kilburn, Tina R.

    Objectives The objective of this PhD. was to examine the relation between low weekly average maternal alcohol consumption and ‘Binge drinking' (defined as intake of 5 or more drinks per occasion) during pregnancy and information processing time (IPT) in children aged five years. Since a method...... to investigate IPT in very young children does not exist, it was decided to develop a method to test this based on Sternberg's paradigm. Method development Sternberg's original method of testing IPT used nine digits in a computer based program, where a subject had to decide whether a shown digit was found...... from a sample of kindergartens in the area of Aarhus, Denmark representing both low and high social economic status. All the versions were somehow able to measure IPT in very young children. However, what for one version seemed to be a shortcoming might have been strength to another. Our conclusion...

  10. Overlapping neurobehavioral circuits in ADHD, obesity, and binge eating: evidence from neuroimaging research.

    Science.gov (United States)

    Seymour, Karen E; Reinblatt, Shauna P; Benson, Leora; Carnell, Susan

    2015-08-01

    Attention-deficit/hyperactivity disorder (ADHD) and conditions involving excessive eating (eg, obesity, binge/loss of control eating) are increasingly prevalent within pediatric populations, and correlational and some longitudinal studies have suggested inter-relationships between these disorders. In addition, a number of common neural correlates are emerging across conditions, eg, functional abnormalities within circuits subserving reward processing and executive functioning. To explore this potential cross-condition overlap in neurobehavioral underpinnings, we selectively review relevant functional neuroimaging literature, specifically focusing on studies probing (i) reward processing, (ii) response inhibition, and (iii) emotional processing and regulation, and we outline 3 specific shared neurobehavioral circuits. Based on our review, we also identify gaps within the literature that would benefit from further research. PMID:26098969

  11. Safety and Tolerability of Desmoteplase Within 3 to 9 Hours After Symptoms Onset in Japanese Patients With Ischemic Stroke

    DEFF Research Database (Denmark)

    Mori, Etsuro; Minematsu, Kazuo; Nakagawara, Jyoji;

    2015-01-01

    intracranial hemorrhage (≤72 hours) was defined as the primary end point. The occurrence of asymptomatic ICH, symptomatic cerebral edemas, and adverse events were other safety outcomes of special interest. RESULTS: Symptomatic intracranial hemorrhage was observed within 72 hours in 2 patients treated with......BACKGROUND AND PURPOSE: This study investigated the safety and tolerability of desmoteplase administered within 3 to 9 hours after stroke symptoms onset in Japanese patients with acute ischemic stroke. METHODS: Patients were randomized to treatment with either desmoteplase or placebo in a 2:1 ratio...... in 2 consecutive cohorts (70 μg/kg and then 90 μg/kg). Included patients had a baseline National Institutes of Health Stroke Scale score of 4 to 24 and occlusion or high-grade stenosis in the middle cerebral artery segment M1 or M2 on magnetic resonance angiography. The incidence of symptomatic...

  12. Cognitive biases in binge eating disorder: the hijacking of decision making.

    Science.gov (United States)

    Voon, Valerie

    2015-12-01

    Binge eating disorder (BED) is the most common of eating disorders and is characterized by excessive, out-of-control, rapid food intake. This review focuses on cognitive impairments in BED, which represent an endophenotype that mediates brain function and behavior. Here we focus on reviewing impulsivity, compulsivity, attentional biases to food cues, and executive function. Behavioral regulation in BED appears to be influenced by the context of motivationally salient food cues and the degree of obesity. Deficits in delay discounting and risk taking under ambiguity are impaired in obesity irrespective of BED status. However, in BED subjects with milder obesity, greater risk seeking under explicit probabilistic risk is observed to monetary rewards, whereas this shifts to risk aversion and enhanced delay discounting in more severe obesity. Relative to non-BED obese subjects, BED is characterized by enhanced behavioral inflexibility or compulsivity across multiple domains, with subjects selecting the same choices despite change in relevance (set shifting), being no longer rewarding (habit formation), or irrespective of outcome (perseveration). The context of food cues was associated with multiple attentional and early and late inhibitory impairments and enhanced memory bias, although BED patients also have generalized cognitive interference in working memory. These findings may help explain the phenotype of binge eating. Motivationally salient food cues provoke attentional and memory biases along with impairing response inhibitory processes. Those with BED are also more susceptible to cognitive interference and have impaired decisional impulsivity, with the tendency to inflexibly stick with the same choices irrespective of changes in context. These findings suggest critical cognitive domains that may guide therapeutic interventions. PMID:26594850

  13. Evaluation of Spirulina Supplementation on Intermittent Binge Ethanol - Induced Neurotoxicity in Dentate Gyrus of Rats

    Directory of Open Access Journals (Sweden)

    M A Asari

    2013-03-01

    Full Text Available Summary. Spirulina is a widely used nutritional supplement which is rich in antioxidants and proteins.  Studies have shown that intermittent binge-like ethanol consumption during adolescent period caused neuronal damage in specific parts of the brain, including the dentate gyrus. It has been suggested that antioxidant therapy may provide some level of protection against neurotoxicity of ethanol at cellular level. Therefore, the purpose of this study was to examine the preventive effects of spirulina supplementation on ethanol-induced neurotoxicity in the dentate gyrus of adolescent rats. Male Sprague-Dawley rats were given ethanol (10 g/kg/day, intermittent binge model, or spirulina platensis (1000 mg/kg/day or both from postnatal day 30 for two weeks duration. The cerebral hemispheres were processed for routine histological staining and immunohistochemistry with anti-GFAP antibody.  Ethanol-treated group showed significant deficit in the numbers of granule cells and hilar neurons of the dentate gyrus when compared to the control group. Spirulina supplementation failed to provide protection against ethanol-induced neuronal loss. Spirulina supplementation also failed to alter increased expression of GFAP immunoreactivity induced by ethanol exposure. In conclusion, these findings indicate that spirulina supplementation is not effective in reducing the ethanol-induced neurotoxicity in the dentate gyrus of adolescent rats. Industrial Relevance. Spirulina is one of the widely used nutritional supplements particularly in Asian population. Being a strong antioxidant, spirulina has been shown to have many therapeutic effects in human. However, the question of whether spirulina supplementation is able to mitigate the effect of ethanol neurotoxicity is largely unknown. Therefore, the study was undertaken to investigate the possibility that spirulina supplementation is able to provide some protection against ethanol-induced neurotoxicity in a rat model

  14. Gender differences in clinical trials of binge eating disorder: An analysis of aggregated data

    Science.gov (United States)

    Shingleton, Rebecca; Thompson-Brenner, Heather; Thompson, Douglas R.; Pratt, Elizabeth M.; Franko, Debra L.

    2015-01-01

    Objective The aim of the study was to examine gender differences in baseline and outcome variables in clinical trials for binge eating disorder (BED). Method Data from 11 randomized controlled psychosocial treatment studies were aggregated (N=1,325: 208 male, 1,117 female). Baseline and outcome symptoms were assessed via the interview and questionnaire versions of the Eating Disorder Examination (EDE). Multilevel analyses were conducted investigating gender differences at baseline and post-treatment, defined as EDE scores, objective binge episode (OBE) reduction, and OBE remission at termination. Results Few males from low SES or minority groups participated in the outcome studies. Males reported significantly lower EDE global, shape, weight, and eating concerns at baseline. No main effects of gender were found in treatment outcome scores when controlling for baseline differences; however, baseline EDE global score (which showed gender differences at baseline) and OBEs directly predicted outcome for both males and females. A significant interaction between gender, treatment length, and shape/weight concerns indicated that males with lower shape/weight concerns achieved OBE remission in shorter treatments, whereas men with high weight/shape concerns and women with either high or low weight/concerns were more likely to achieve OBE remission in treatments of longer duration. Conclusions These results suggest BED treatment studies must improve their recruitment of men and appeal to men with lower shape/weight concerns. Additionally, longer-term treatments, while more efficacious for women and men with more severe shape/weight concerns, may not be necessary for men with low shape/weight concerns. PMID:25730521

  15. Bing Maps: aerofotointerpretazione archeologica online. La visione panoramica “made in Microsoft”

    Directory of Open Access Journals (Sweden)

    Davide Mastroianni

    2014-10-01

    Full Text Available In the last years, the aerial archaeology confirmed the importance and the potentiality of aerial photography in the study of landscape that already was realized by Giacomo Boni, Franz Stolze and O.G.S. Crawford between the late nineteenth and the early twentieth century. Aerial photography is today a tool used in numerous fields: from geology to civil engineering, from the study of the environment to the identification of pollution sources, from architecture to archeology; in fact it is becoming a valid and indispensable tool for the study of the ancient topography. In this last field, the aerial photograph is really important if it is used as instrument of knowledge and research. The aerial view is sure the most useful tool for observe the modern landscape and all evidence or “marks” that would be unintelligible if they are observed from the ground. The great diffusion of internet has made possible the creation of catalogues that allow consulting maps, orthophotos, aerial and oblique images online; the Italian regions have decided to publish all data on internet with the creation of websites (WebGIS. However, it is possible to encounter serious difficulties in finding the photographic material because of high costs and long times, but thanks to the use of Bing Maps, a web mapping service of Microsoft™, it is possible to break down such restrictions. Bing Maps has high resolution oblique photographs, so called “Bird’s Eye”, that allow to realize a free virtual aerial survey thanks to combined use of aerial and oblique images. This approach has been used to observe the modern landscape of Veio obtaining new archaeological useful data, without cost, for the reconstruction and update of ancient topography of Etruscan town.

  16. 72区注水开发评价%Chuan 72 Area Water Injection Evaluation

    Institute of Scientific and Technical Information of China (English)

    黄博

    2015-01-01

    This paper expounds geological survey,geology and reservoir characteristics,reservoir engineering,water injection deployment,water injection crafts in chuan 72 area water injection evaluation.%本文从区域地质概况、地质与油藏特征、油藏工程、注水开发部署、注水工艺五个方面对川72区注水开发进行了评价。

  17. 29 CFR 553.221 - Compensable hours of work.

    Science.gov (United States)

    2010-07-01

    ... Compensable hours of work. (a) The general rules on compensable hours of work are set forth in 29 CFR part 785... 29 Labor 3 2010-07-01 2010-07-01 false Compensable hours of work. 553.221 Section 553.221 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS...

  18. 46 CFR 9.9 - Two hours between broken periods.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Two hours between broken periods. 9.9 Section 9.9... COMPENSATION FOR OVERTIME SERVICES § 9.9 Two hours between broken periods. Where 2 hours or more intervene between broken periods, one-half day's extra pay will be allowed for each distinct 2-hour period or...

  19. Comparing the Detection of Transdermal and Breath Alcohol Concentrations during Periods of Alcohol Consumption Ranging from Moderate Drinking to Binge Drinking

    OpenAIRE

    Dougherty, Donald M.; Charles, Nora E.; Acheson, Mr. Ashley; John, Samantha; Furr, R. Michael; Hill-Kapturczak, Nathalie

    2012-01-01

    Binge drinking is a public health concern due to its association with negative health outcomes as well as increased legal and social consequences. Previous studies have frequently used self-reported alcohol consumption to classify binge drinking episodes; however, these measures are often limited in both detail and accuracy. Some researchers have begun using additional measures such as blood (BAC) and breath (BrAC) alcohol concentrations to supplement self-report data. Transdermal alcohol tes...

  20. Adolescent binge drinking leads to changes in alcohol drinking, anxiety, and amygdalar corticotropin releasing factor cells in adulthood in male rats.

    Directory of Open Access Journals (Sweden)

    Nicholas W Gilpin

    Full Text Available Heavy episodic drinking early in adolescence is associated with increased risk of addiction and other stress-related disorders later in life. This suggests that adolescent alcohol abuse is an early marker of innate vulnerability and/or binge exposure impacts the developing brain to increase vulnerability to these disorders in adulthood. Animal models are ideal for clarifying the relationship between adolescent and adult alcohol abuse, but we show that methods of involuntary alcohol exposure are not effective. We describe an operant model that uses multiple bouts of intermittent access to sweetened alcohol to elicit voluntary binge alcohol drinking early in adolescence (~postnatal days 28-42 in genetically heterogeneous male Wistar rats. We next examined the effects of adolescent binge drinking on alcohol drinking and anxiety-like behavior in dependent and non-dependent adult rats, and counted corticotropin-releasing factor (CRF cell in the lateral portion of the central amygdala (CeA, a region that contributes to regulation of anxiety- and alcohol-related behaviors. Adolescent binge drinking did not alter alcohol drinking under baseline drinking conditions in adulthood. However, alcohol-dependent and non-dependent adult rats with a history of adolescent alcohol binge drinking did exhibit increased alcohol drinking when access to alcohol was intermittent. Adult rats that binged alcohol during adolescence exhibited increased exploration on the open arms of the elevated plus maze (possibly indicating either decreased anxiety or increased impulsivity, an effect that was reversed by a history of alcohol dependence during adulthood. Finally, CRF cell counts were reduced in the lateral CeA of rats with adolescent alcohol binge history, suggesting semi-permanent changes in the limbic stress peptide system with this treatment. These data suggest that voluntary binge drinking during early adolescence produces long-lasting neural and behavioral effects