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Sample records for 60co gamma-rays irradiation

  1. Study on shelf life extension of papayas irradiated by /sup 60/Co gamma-rays

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    Chang, M.S.; Chen, M.D.; Lin, C.T.; Fu, Y.K.

    1984-11-01

    Papayas are one of the main fresh fruits in Taiwan area. Papaya fruits were treated with hot water to pasteurize peels followed by /sup 60/Co gamma-ray irradiation to extend the ripening time. The purpose of synergetic methods is to extend the shelf life of papaya fruits. This experiment was carried out by seven treatments, which were: (1) control group, (2) hot water treatment only, (3) hot water treatment with a 25 krad ..gamma..-irradiation, (4) hot water treatment with a 50 krad ..gamma..-irradiation, (5) hot water treatment with a 75 krad ..gamma..-irradiation, (6) 75 krad ..gamma..-irradiation only, and (7) hot water treatment with a 100 krad ..gamma..-irradiation. The items of observation were: surface yellowing, surface decaying, quality of texture, and length of period lasted after irradiation for 50% marketable papayas. The results of this study showed that a shelf-life extension of six days could be obtained for papayas subjected to hot water (50 to 55/sup 0/C) treatment and a 100 krad irradiation. 3 refs., 2 figs., 2 tabs.

  2. Study of irradiated bothropstoxin-1 with {sup 60}Co gamma rays: immune system behavior

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    Caproni, P.; Baptista, J.A.; Almeida, T.L. de; Nascimento, N. [Nuclear and Energy Research Institute (IPEN/CNEN-SP), SP (Brazil). Biotechnology Center; Passos, L.A.C. [State University of Campinas (UNICAMP), SP (Brazil). Lab. of Genetics and Embryo Cryopreservation

    2009-07-01

    Ionizing radiation has been successfully employed to modify the immunological properties of biomolecules. Very promising results were obtained when crude animal venoms, as well as isolated toxins, were treated with 60Co gamma rays, yielding toxoids with good immunogenicity. The achievement of modified antigens with lower toxicity and preserved or improved immunogenicity can be very useful. Ionizing radiation has already been proven to be a powerful tool to attenuate snake venom toxicity without affecting, and even increasing, their immunogenic properties. However, little is known about the modifications that irradiated molecules undergo and even less about the immunological response that such antigens elicit. In the present work, we investigated the immunological behavior of bothropstoxin-1, a K49 phospholipase, before and after irradiation. Structural modifications of the toxin were analyzed by SDS-PAGE. Isogenic mice were immunized with either the native or the irradiated toxin. The circulating antibodies were isotyped and titrated by ELISA. According to our data, irradiation promoted structural modifications in the toxin characterized by higher molecular weight forms of proteins (aggregates and oligomers). The results also indicated that irradiated toxins were immunogenic and antibodies elicited by them were able to recognize the native toxin in ELISA. These findings suggest that irradiation of toxic proteins can promote significant modifications in their structures; however they still retain many of the original antigenic and immunological properties of native proteins. Also, our data indicate that irradiated proteins induce higher titers of IgG2a and IgG2b, suggesting that Th1 cells are predominantly involved in the immune response. (author)

  3. Study of irradiated toxins with {sup 60}Co gamma rays: immune system behavior

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    Caproni, Priscila; Baptista, Janaina A.; Almeida, Tiago Luiz de; Passos, Luiz A.C.; Nascimento, Nanci do [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: pricaproni@hotmail.com

    2007-07-01

    Ionizing radiation has been successfully employed to modify the immunological properties of biomolecules. Very promising results were obtained when crude animal venoms, as well as isolated toxins, were treated with {sup 60}Co gamma rays, yielding toxoids with good immunogenicity. The achievement of modified antigens with lower toxicity and preserved or improved immunogenicity can be useful. Ionizing radiation has been proven to be a powerful tool to attenuate snake venoms toxicity without affecting and even increasing their immunogenic properties. However, little is known about the modifications that irradiated molecules undergo and even less about the immunological response that such antigens elicit. In the present work, we have investigated the immunological behavior of bothropstoxin-I, a K49 phospholipase, before and after irradiation. Structural modifications of the toxin were investigated by SDS-PAGE. Isogenic mice were immunized with either the native or the irradiated toxin. The circulating antibodies were isotyped and titrated by ELISA. According to our data, irradiation promoted structural modifications in the toxin, characterized by higher molecular weight forms of the protein (aggregates and oligomers). Our data indicate that irradiated toxins were immunogenic and the antibodies elicited by them were able to recognize the native toxin in ELISA. These results indicate that irradiation of toxic proteins can promote significant modifications in their structures, but still retain many of the original antigenic and immunological properties of native proteins. Also, our data indicate that the irradiated protein induced higher titers of IgG2a and IgG2b, suggesting that Th1 cells were predominantly involved in the immune response. (author)

  4. Effects of 2. 0 Gy of /sup 60/Co gamma rays irradiation on rat embryos

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    Lee, Juing-Yi; Satow, Yukio

    1987-01-01

    Pregnant rats of Donryu strain were exposed to a whole-body /sup 60/Co ..gamma.. ray irradiation of a single dose of 2.0 Gy (Dose rate: 0.5 Gy/min) on day 7, 8, 9, 10 or 11 of gestation (sperm day = day 0). The rats were sacrificed on day 18 and the offspring were examined for external and visceral malformations. Malformed embryos occurred between days 7 and 11 with the highest incidence occurring on day 9. Dose with 2.0 Gy increased the rate of resorption or death (52.1 %), in the survivors, caused congenital malformation in a majority of embryos (86.5 %) on day 8 of gestation. There is an increase in malformation (93.3 %) and growth retardation, but no increase in mortality (42.9 %) on day 9 of gestation. Relatively few anomalies resulted from irradiation on day 7 of gestation. The peak day for cardiovascular anomalies occurred on day 9 (88.3 % of all survival embryos) with high levels also occurring on day 8 (86.5 %). Cardiovascular anomalies consisted of VSD, hypoplasia of the pulmonary trunk, coarctation of the aorta, double aortic arch, right aortic arch, riding aorta, complete transposition of the aorta, persistent atrioventricular canal, vascular ring, aberrant right subclavian artery and others. Similar anomalies, but at a lower incidence, were produced by /sup 60/Co ..gamma.. ray at dose levels of 2.0 Gy on day 10 or 11 of gestation. Cases of cleft lip and cleft palate or facial cleft were observed seventeen fetuses on day 9 of gestation (31 %). Exencephaly occurred in nine embryos treated on day 9 (16.1 %) and in one embryos treated on day 10. Tail defects appeared with treatment on day 9 with the latter predominating on day 11. The present study show that maximum resorption (52.1 %) was seen with treatment on day 8 whereas the highest rate of malformation (93.3 %) was observed with treatment on day 9. (J.P.N.).

  5. Perna perna (LINNAEUS, 1758) mussels irradiated by {sup 60}CO gamma rays cytotoxicity evaluation

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    Martini, Gisela A.; Pusceddu, Fabio H.; Rogero, Sizue O.; Rogero, Jose Roberto, E-mail: gisela.martini@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    The aim of the present work was the study of ionizing radiation effects on aquatic biota regarding the location of nuclear facilities nearby coastal areas assuming the risk of leaks and nuclear accidents. Bivalve mollusks have been widely used in the monitoring of aquatic environment studies mainly for their sessile habit and pollutants bioconcentration ability. So marine mussel Perna perna (Bivalvia: Mytilidae) was used as organism test in this study. The study of radioactive toxicity was performed by cytotoxicity test exposing the organisms to 11Gy gamma radiation dose. After radiation the neutral red retention assay evaluated the lysosomal membrane integrity in the mussel hemocytes. 50% lethal dose assay (LD50) of gamma radiation on Perna perna mussels was carried out by exposure the organisms to {sup 60}Co gamma rays at doses ranging from 0 to 3000 Gy. The result of gamma radiation LD50 for these mussels was 1068 Gy and the neutral red retention time of irradiated organisms was about 47% lower than the control, non irradiated organisms. With the obtained results is expected to contribute in the study to identify the range of ionizing radiation doses which can cause toxic effects in marine invertebrates. (author)

  6. Evaluation of myotoxic activity of Bothropstoxin-1 irradiated with {sup 60}Co gamma rays

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    Mirco, Jessica; Baptista, Janaina A.; Caproni, Priscila; Yoshito, Daniele; Nascimento, Nanci do [Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN/SP), Sao Paulo, SP (Brazil)], e-mail: jessica.mirco@yahoo.com.br, e-mail: janabap@gmail.com, e-mail: pricaproni@hotmail.com, e-mail: daniyoshito@uol.com.br, e-mail: nnascime@ipen.br

    2009-07-01

    Ionizing radiation has been successfully employed to modify the immunological properties of biomolecules and has been proven to be a powerful tool to attenuate snake venoms toxicity without affecting their immunogenic properties. Snake venoms and their isolated toxins showed structural modifications after gamma radiation process, in aqueous solution, mainly by water radiolysis sub products. Free radical scavengers, such as NaNO{sub 3} and t-butanol, present selective effects on specific radical from water radiolysis. The NaNO{sub 3} has affinity by aqueous electron, while the t-butanol has affinity by hydroxyl radical. At the present work, we have investigated the myotoxic activity of Bothropstoxin-1 (BTHX-1), a K49 phospholipase, present in Bothrops jararacussu crude venom, before and after irradiation process, with or without scavenger substances presence. BTHX-1 was irradiated with 2 kGy of {sup 60}Co gamma rays, in aqueous solution and in the presence of oxygen. BALB/c mice were inoculated with either native or irradiated toxin, with or without scavenger substances. After 3 hours, blood samples were collected and the myotoxic activity was evaluated by LDH (lactate dehydrogenase) release. The muscular tissue damage was directly related to the LDH amounts released. Irradiated Bothropstoxin-1, with or without NaNO{sub 3} substance, caused less damage than their native counterpart. But irradiated toxin, in the presence of t-butanol, was so myotoxic as the native BTHX-1. These results indicate that irradiation of toxic proteins can promote significant modifications on their structures, but still retaining many of the original biological properties of their native counterparts. Additionally, some scavengers substances can change these gamma radiation effects. (author)

  7. Dose intercomparison studies for 60Co gamma-ray and electron beam irradiation in the year 2002

    Institute of Scientific and Technical Information of China (English)

    LIN Min; Takuji KOJIMA; Zofia PEIMEL-STUGLIK; CHEN Yun-Dong; CUI Ying; CHEN Ke-Sheng; LI Hua-Zhi; XIAO Zhen-Hong; Slawomir FABISIAK

    2004-01-01

    Dose inter-comparison studies for 60Co γ-ray and 10MeV electron beam irradiation were carried out from July to October in 2002. The purpose of the studies was to check the reliability of the alanine-PE film dosimeters made by CIAE, which will be used as transfer standard dosimetry system mainly for electron beam irradiation.The expanded uncertainty of CIAE alanine/EPR dosimetry system was 4.1% for doses not higher than 10 kGy and 5.4% for those above 10 kGy (k=2). CIAE alanine-PE film dosimeters were sent to JAERI, RISO (National Laboratory in Denmark) and INCT respectively, which were irradiated by 60Co gamma-rays or electron beams in each laboratory. The irradiated dosimeters were then sent back to CIAE for electron paramagnetic resonance (EPR) analysis.The agreements were obtained to be ±1.9% for gamma-ray dose measurement and ±4.3% for electron beam dose measurement, which were all within the combined uncertainty of the reference and CIAE alanine/EPR dosimetry system. Furthermore, the overall mean ratio was found to be 0.995 with 1.8% in the coefficient of variation (CV). The preliminary inter-comparison studies indicated that CIAE film alanine/EPR dosimetry system had the potential to be used as a transfer dosimetry system for high dose measurement.

  8. Immune response against bothropstoxin-I irradiated with {sup 60}Co gamma rays

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    Baptista, J.A.; Spencer, P.J.; Higa, O.Z.; Casare, M.S.; Campos, L.A.; Nascimento, N. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Lab. de Biologia Molecular]. E-mail: janabap@gmail.com; Andrade Junior, H.F de [Sao Paulo Univ., SP (Brazil). Inst. de Medicina Tropical de Sao Paulo. Lab. de Protozoologia]. E-mail: hfandrad@usp.br

    2005-07-01

    Ionizing radiation has been successfully employed to modify the immunological properties of biomolecules. Very promising results were obtained when crude animal venoms, as well as isolated toxins, were treated with gamma rays, yielding toxoids with good immunogenicity. Ionizing radiation has proven to be a powerful tool to attenuate snake venoms toxicity without affecting and even increasing their immunogenic properties. However, little is known about the modifications that irradiated molecules undergo and even less about the immunological response that such antigens elicit. In the present work, we investigated the immunological behavior of bothropstoxin-I, a K49 phospholipase, before and after irradiation. Structural modifications of the toxin were investigated by SDS-PAGE and mass spectrometry. Aiming to compare the toxicity between native and irradiated forms of the toxin, an in vitro cytotoxicity assay, using CHO cells, was performed. Isogenic mice were immunized with either the native or the irradiated toxin. The circulating antibodies were isotyped and titrated by ELISA. According to our data, irradiation promoted structural modifications in the toxin, characterized by higher molecular weight forms of the protein (aggregates and oligomers). When analyzed by mass spectrometry, the irradiated bothropstoxin appeared in several oxidized forms. The cytotoxicity assay showed that the modified toxin was 5 folds less toxic than its native counterpart. Irradiated toxins were immunogenic and the antibodies elicited by them were able to recognize the native toxin in ELISA. These results indicate that irradiation of toxic proteins can promote significant modifications in their structures, but still retain many of the original immunological properties. (author)

  9. Irradiation effect on enzymatic activity of papain with {sup 60}Co-{gamma} rays

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    Furuta, Masakazu; Ohashi, Isao; Oka, Masahito; Hayashi, Toshio [Osaka Prefecture Univ., Sakai (Japan). Research Inst. for Advanced Science and Technology

    1998-12-31

    An investigation was made on the durability of enzyme activity against {sup 60}Co-{gamma} irradiation at a dose up to 55 kGy/h using dry powder and aqueous solution of papain preparations on the market. Hybrid materials including bioactive molecules combined with biocompatible synthetic polymers are expected to have biocompatible properties and also biomimetic functions as a component of artificial organs for human body. The activity of papain in an aqueous solution was rapidly decreased at the early stage of irradiation through oxidation of SH group at its active site with active oxygen produced by the irradiation and then, partially recovered since SH group was reproduced in an anoxic state after O{sub 2} consumption in the solution irradiated at a high dose. A usual radiation method for sterilization was found applicable to decontamination of dry and frozen preparations of papain. When suitable conditions for radiation were chosen and N{sub 2} gas was purged to suppress the formation of free radicals, it was possible to keep the enzyme activity at more than 50% of the initial activity after radiation at 30 kGy. (M.N.)

  10. Biochemical and pharmacological characterization of irradiated crotamine by gamma rays of {sup 60}Co; Caracterizacao bioquimica e farmacologica da crotamina irradiada por raios gama de {sup 60}Co

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    Oliveira, Karina Corleto

    2014-07-01

    The serum production in Brazil, the only effective treatment in cases of snakebites, uses horses that although large size, have reduced l lifespan compared with horses not immunized. Ionizing radiation has been shown as an excellent tool in reducing the toxicity of venoms and toxins isolated, and promote the achievement of better immunogens for serum production, and contributing to the welfare of serum-producing animals. It is known, however, that the effects of ionizing radiation on protein are characterized by various chemical modifications, such as fragmentation, cross-linking due to aggregation and oxidation products generated by water radiolysis. However, the action of gamma radiation on toxins is not yet fully understood structurally and pharmacologically, a fact that prevents the application of this methodology in the serum production process. So we proposed in this paper the characterization of crotamine, an important protein from the venom of Crotalus durissus terrificus species, irradiated with {sup 60}Co gamma rays. After isolating the toxin by chromatographic techniques and testing to prove the obtaining of pure crotamine, it was irradiated with gamma rays and subjected to structural analysis, Fluorescence and Circular Dichroism. Using high hydrostatic pressure tests were also conducted in order to verify that the conformational changes caused by radiation suffer modifications under high pressures. From the pharmacological point of view, muscle contraction tests were conducted with the objective of limiting the action of crotamine in smooth muscle as well as the change in the action of toxin caused structural changes to the front. Analysis of Circular Dichroism and Fluorescence showed changes in structural conformation of crotamine when subjected to gamma radiation and that such changes possibly occurring in the secondary and tertiary structure of the protein. The observed in pharmacological tests showed that the irradiated crotamine was less effective

  11. Structure alteration and immunological properties of {sup 60}Co gamma rays irradiated bothropstoxin-I

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    Baptista, Janaina A.; Yonamine, Camila Myiagui; Caproni, Priscila; Casare, Murilo; Spencer, Patrick Jack; Nascimento, Nanci do [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: janabap@gmail.com; Andrade Junior, Heitor Franco de; Vieira, Daniel Perez; Galisteo Junior, Andres Jimenez [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Instituto de Medicina Tropical de Sao Paulo, SP (Brazil). Lab. de Protozoologia

    2007-07-01

    About 20000 ophidic accidents are registered every year in Brazil. Serum therapy with equine antisera is the only efficient treatment. The venoms employed for immunization are fairly toxic and some venoms present low immunogenicity. Thus, the obtention of modified antigens with lower toxicity and preserved or improved immunogenicity would be useful. These toxins, when submitted to gamma radiation, in aqueous solution, present structural modifications. This occurs due to reactions with the radiolysis products of water. Some scavenger substances, such as NaNO{sub 3} and t-butanol, remove selectively the water radiolysis products. Ionizing radiation has proven to be a powerful tool to attenuate snake venoms toxicity without affecting and even increasing their immunogenic properties. However, the immune mechanisms involved in recognition, processing and presentation of irradiated antigens are yet unclear. In the present work, we investigated the immunological behavior of bothropstoxin-I (Bthx-1), before and after irradiation, in the presence of selective scavengers. Isogenic mice were immunized with either the native or the irradiated toxin, either with or without scavengers. After three immunizations, serum samples were collected and the antibody titers and isotypes were determined by Enzyme Linked Immuno Sorbent Assay. The antigenic characterization of native and irradiated bothropstoxin-I was performed by Western blot. The detection of expression of murine cytokines (IFN-{gamma} and IL-10) was analyzed by RT-PCR (Reverse Transcriptase-Polymerase Chain Reaction). According to our data, irradiation process has promoted structural modifications in the toxin, characterized by higher molecular weight forms of the protein (aggregates and oligomers). Our data also indicate that irradiated toxins, alone or in the presence of NaNO{sub 3}, an aqueous electron scavenger, were immunogenic and the antibodies elicited by them were able to recognize the native toxin. On the other

  12. Comparison of base substitutions in response to nitrogen ion implantation and 60Co-gamma ray irradiation in Escherichia coli

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    Xie Chuan-Xiao

    2004-01-01

    Full Text Available To identify the specificity of base substitutions, a novel experimental system was established based on rifampicin-resistant (Rif r mutant screening and sequencing of the defined region of the rpoB gene in E. coli. We focused on comparing mutational spectra of base substitutions induced by either low energy nitrogen ion beam implantation or 60Co-gamma rays. The most significant difference in the frequency of specific kinds of mutations induced by low energy nitrogen ion beam was that CG ®TA transitions were significantly increased from 32 to 46, AT ®TA transversions were doubled from 7 to 15 in 50 mutants, respectively. The preferential base substitutions induced by nitrogen ion beam implantation were CG ®TA transitions, AT ®GC transitions, AT ®TA transversions, which account for 92.13% (82/89 of the total. The mutations induced by 60Co-gamma rays were preferentially GC ®AT and AT ®GC transitions, which totaled 84.31% (43/51.

  13. 白藜芦醇对60Coγ射线照射小鼠氧化损伤的防护%Radioprotective Effect of Resveratrol on Oxidative Damage in 60Co Gamma Ray Irradiated Mice

    Institute of Scientific and Technical Information of China (English)

    徐冰心; 李成林; 史煜华; 谢京波; 陈阿鑫; 高娇; 任晔; 李建忠; 刘志国

    2012-01-01

    Objective To investigate the radioprotective effect of resveratrol( RES) on gamma-irradiation-induced serum and liver oxidative damage in mice. Methods Thirty male ICR mice were randomized into 5 groups; normal control group, irradiated control group, RES 50,100 and 200 mg·kg-1 irradiated groups. RES was administered respectively to three dosage groups by gavage on 3rd day before irradiation and 7th day after irradiation. Except for normal control, all the mice were whole-body irradiated by 60Co gamma ray(a single dose of 6.0 Gy). The mice were killed on 7th day. The activities of superoxide dismutase (SOD) ,glutathione peroxidase (GSh-Px) and the amount of malondialdehyde( MDA) of the serum and liver were measured. Results Compared with normal control group,the activities of SOD and GSH-Px were significantly decreased while the amount of MDA was significantly increased in irradiated control group mice. Compared with irradiated control, the activities of SOD and GSH-Px tended to increase while the amount of MDA tended to decrease in RES 50 mg ·kg-1' irradiated group mice. The activities of SOD and GSh-Px and the amount of MDA increased with the RES dosage. Conclusion RES has radioprotective effect against oxidative damage to the serum and liver in 60Co rays irradiated mice. This effect of RES depends on the dosage.%目的 研究白藜芦醇对60Coγ射线照射小鼠氧化损伤的防护作用.方法 30只♂ ICR小鼠随机分成5组,正常对照组、照射对照组以及白藜芦醇低、中、高剂量( 50、100、200 mg·kg-1)照射组,照射前3d至照后第7天灌服给药,每天1次,共10次.除正常对照组外,所有小鼠60Coγ射线全身6 Gy辐照1次,照射后第7天小鼠取外周血和肝组织标本,测定血清和肝组织匀浆中超氧化物歧化酶(SOD)、谷胱苷肽过氧化物酶(GSH-Px)活性及丙二醛(MDA)含量.结果与正常对照组比较,照射对照组小鼠血清和肝组织匀浆中SOD和GSH-Px活性显著下降,MDA含量显

  14. A comparison of ionizing radiation damage in CMOS devices from 60Co gamma rays, electrons and protons

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    HE Sao-Ping; YAO Zhi-Bin; ZHANG Feng-Qi

    2009-01-01

    Radiation hardened CC4007RH and non-radiation hardened CC4011 devices were irradiated using 80Co gamma rays, 1 MeV electrons and 1--9 MeV protons to compare the ionizing radiation damage of the gamma rays with the charged particles. For all devices examined, with experimental uncertainty, the radiation induced threshold voltage shifts (△Vth) generated by 60Co gamma rays are equal to that of 1 MeV electron and 1-7 MeV proton radiation under 0 gate bias condition. Under 5 V gate bias condition, the distinction of threshold voltage shifts (△Vth) generated by 60Co gamma rays and 1 MeV electrons irradiation are not large, and the radiation damage for protons below 9 MeV is always less than that of 60Co gamma rays. The lower energy the proton has, the less serious the radiation damage becomes.

  15. Sensitivity to. gamma. rays of avian sarcoma and murine leukemia viruses. [/sup 60/Co, uv

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    Toyoshima, K. (Osaka Univ., Japan); Niwa, O.; Yutsudo, M.; Sugiyama, H.; Tahara, S.; Sugahara, T.

    1980-09-01

    The direct inactivation of avian and murine oncoviruses by ..gamma.. rays was examined using /sup 60/Co as a ..gamma..-ray source. The inactivation of murine leukemia virus (M-MuLV) followed single-hit kinetics while the subgroup D Schmidt-Ruppin strain of avian sarcoma virus (SR-RSV D) showed multihit inactivation kinetics with an extrapolation number of 5. The two viruses showed similar uv-inactivation kinetics. The genomic RNA of the SR-RSV D strain was degraded by ..gamma.. irradiation faster than its infectivity, but viral clones isolated from the foci formed after ..gamma.. irradiation had a complete genome. These results suggest that SR-RSV D has a strong repair function, possibly connected with reverse transcriptase activity.

  16. IMMUNE TOLERANCE INDUCED BY GAMMA-RAY IRRADIATION

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    练燕; 王延江; 粟永萍; 冉新泽; 艾国平; 刘晓宏; 郭朝华; 程天民

    2003-01-01

    Objective: To detect the existence of immune tolerance induced by gamma-ray irradiation. Methods: Peritoneal cells were harvested from mice subjected to 5 Gy 60Co gamma-ray total body irradiation at 3d, 7d, 15d and 30d, then their counts, morphological changes and IL-12 gene expression were investigated. Results: After irradiation, the peritoneal cells were sharply reduced, the cell morphology shifted from round-like to polymorphic and fusiform with some processes, expression of IL-12 p35 was seriously suppressed, while that of IL-12 p40 greatly enhanced. Conclusion: Our data highly suggest that the gamma-ray irradiation could potentially induce dendritic cell (DC) commitment and immune tolerance.

  17. Influence of gamma ray irradiation on metakaolin based sodium geopolymer

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    Lambertin, D., E-mail: david.lambertin@cea.fr [CEA, DEN, DTCD/SPDE/LP2C, F-30207 Bagnols-sur-Cèze (France); Boher, C. [CEA, DEN, DTCD/SPDE/LP2C, F-30207 Bagnols-sur-Cèze (France); Dannoux-Papin, A. [CEA, DEN, DTCD/SPDE/LCFI, F-30207 Bagnols-sur-Cèze (France); Galliez, K.; Rooses, A.; Frizon, F. [CEA, DEN, DTCD/SPDE/LP2C, F-30207 Bagnols-sur-Cèze (France)

    2013-11-15

    Effects of gamma irradiation on metakaolin based Na-geopolymer have been investigated by external irradiation. The experiments were carried out in a gamma irradiator with {sup 60}Co sources up to 1000 kGy. Various Na-geopolymer with three H{sub 2}O/Na{sub 2}O ratios have been studied in terms of hydrogen radiolytic yield. The results show that hydrogen production increases linearly with water content. Gamma irradiation effects on Na-geopolymer microstructure have been investigated with porosity measurements and X-ray pair distribution function analysis. A change of pore size distribution and a structural relaxation have been found after gamma ray irradiation.

  18. Influence of gamma ray irradiation on metakaolin based sodium geopolymer

    Science.gov (United States)

    Lambertin, D.; Boher, C.; Dannoux-Papin, A.; Galliez, K.; Rooses, A.; Frizon, F.

    2013-11-01

    Effects of gamma irradiation on metakaolin based Na-geopolymer have been investigated by external irradiation. The experiments were carried out in a gamma irradiator with 60Co sources up to 1000 kGy. Various Na-geopolymer with three H2O/Na2O ratios have been studied in terms of hydrogen radiolytic yield. The results show that hydrogen production increases linearly with water content. Gamma irradiation effects on Na-geopolymer microstructure have been investigated with porosity measurements and X-ray pair distribution function analysis. A change of pore size distribution and a structural relaxation have been found after gamma ray irradiation.

  19. Microstructural study of Y{sub 1}Ba{sub 2}Cu{sub 3}O{sub 7-x}/Ag samples irradiated with {sup 60}Co {gamma} rays at high doses

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    Rangel, R. [Programa de Postgrado en Fisica de Materiales, Centro de Investigacion Cientifica y de Educacion Superior de Ensenada, Apartado Postal 2681, CP 22800, Ensenada, BC (Mexico); Galvan, D.H. [CECIMAC-UNAM, Apartado Postal 2681, CP 22800, Ensenada, BC (Mexico); Adem, E. [Instituto de Fisica-UNAM, Apartado Postal 20-364, CP 01000, Mexico DF (Mexico); Bartolo-Perez, P. [CINVESTAV-IPN Unidad Merida, Departamento de Fisica Aplicada, Merida, Yucatan (Mexico); Maple, M.B. [Physics Department and Institute for Pure and Applied Physical Sciences, La Jolla, CA (United States)

    1998-06-01

    We have investigated the damage induced by irradiation in Y{sub 1}Ba{sub 2}Cu{sub 3}O{sub 7-x} silver added samples. The samples were prepared with 0 and 6.5 wt% of silver and irradiated by high-energy {gamma} irradiation (50-150 Mrad). The roles of silver and dosage irradiation are discussed in terms of their effects on microstructure, crystallinity, critical temperature (T{sub c}) and zero-resistance temperature (T{sub 0}). After irradiation, T{sub c} decreased while the room-temperature electrical resistance increased by a factor of 8 for some of the samples. The difference in T{sub 0} between irradiated and non-irradiated YBCO samples was of the order of 10 K. We have found that the difference is bigger for silver-added samples. We have also observed several changes in diffraction patterns of YBCO and YBCO-silver samples. SEM images, EDS and XPS analysis showed that silver resided inside the grains as single atoms and as metallic clusters. The relative concentrations of the elements in samples were quantified by Auger electron spectroscopy. The values showed a gradual increase for radiation doses ranging between 0 and 100 Mrad. For doses up to 100 Mrad, J{sub c} decreased because of the weak-link breakage induced by high doses of {gamma} rays. (author)

  20. Determination of late-time Gamma-Ray (60Co) sensitivity of single diffusion Lot 2N2222A transistors.

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    DePriest, Kendall Russell; Kajder, Karen C.; Peters, Curtis D. (American Staff Augmentation Providers, LLC, Albuquerque, NM)

    2008-08-01

    Sandia National Laboratories (SNL) has embarked on a program to develop a methodology to use damage relations techniques (alternative experimental facilities, modeling, and simulation) to understand the time-dependent effects in transistors (and integrated circuits) caused by neutron irradiations in the Sandia Pulse Reactor-III (SPR-III) facility. The development of these damage equivalence techniques is necessary since SPR-III was shutdown in late 2006. As part of this effort, the late time {gamma}-ray sensitivity of a single diffusion lot of 2N2222A transistors has been characterized using one of the {sup 60}Co irradiation cells at the SNL Gamma Irradiation Facility (GIF). This report summarizes the results of the experiments performed at the GIF.

  1. Radiation quality of tritium: a comparison with 60Co gamma rays.

    Science.gov (United States)

    Chen, Jing

    2013-09-01

    In a previous study, microdosimetric simulations were performed for tritium uniformly distributed in a medium, and for tritium bound to biologically critical sites of dimensions from 10 nm to 2 µm. Results of local energy density, i.e. energy deposition in microscopic regions, are different for these two cases. Based on the spatial distribution of energy deposition, dose mean lineal energies are calculated for tritium in the forms of tritiated water (HTO) and organically bound tritium (OBT). The dose mean lineal energies of OBT are about a factor of 1.7 higher than those of HTO in a wide range of target dimensions of biological interest. The results are consistent with radiobiological findings that OBT is about twice as effective as HTO. In this study, the same calculations were performed for (60)Co gamma rays in a wide range of target dimensions of biological interest (10 nm to 2 µm). Compared with (60)Co gamma rays, the estimated relative biological effectiveness could vary from 1.3 to 3.5 for HTO, and 2.3 to 5.6 for OBT. The results are consistent with radiobiological findings for various biological endpoints in different biological systems that OBT is about twice as effective as HTO.

  2. Different gamma ray ({sup 60} Co) dose effects on Sorghum genotype germination; Efeito de diferentes doses de radiacao gama do {sup 60} Co sobre a germinacao de genotipos de sorgo (Sorghum bicolor)

    Energy Technology Data Exchange (ETDEWEB)

    Tabosa, Jose Nildo; Gomes, Roberto Vicente; Reis, Odemar Vicente dos [Empresa Pernambucana de Pesquisa Agropecuaria (IPA), Recife (Brazil)]. E-mail: tabosa@ipa.br; Colaco, Waldeciro [Universidade Federal de Pernambuco, Recife, PE (Brazil). Dept. de Energia Nuclear]. E-mail: wcolaco@ufpe.br

    2004-08-15

    In agriculture, applying irradiation is a very valuable way of obtaining vegetable products for human and animal consumption. Cobalt-60, one of the main sources of gamma-rays, is considered an important tool in plant breeding programs, which have the objective of promoting genetic variability of cultivars with resistance to adverse environments. In this research, the effects of different {sup 60}Co doses on germination vigor and seed germination velocity of forage sorghum genotypes were evaluated. The study was carried out at the IPA (Empresa Pernambucana de Pesquisa Agropecuaria) in Recife, Pernambuco, Brazil. The work was installed in germination boxes, following laboratory recommendations. Thus, a experiment involving three sorghum genotypes (IPA 467-4-2, IPA 02-03-01, and Sudan 4202), five {sup 60}Co doses (Zero, 150, 300, 350, and 400 Gy), was set up. The sees were irradiated before the beginning of the experiment being exposed to gamma rays from a {sup 60}Co-source (cobalt irradiator) at DEN (Nuclear Engineering Department) of the UFPE (Pernambuco Federal University), Brazil. The work also had the objective of evaluating the sorghum genotypes x {sup 60}Co dose interaction. The main results obtained showed that the sorghum genotype IPA 02-03-01 presented the greatest values of germination and vigor percentages, and seed germination velocity, when compared to the others evaluated, on 350 and 400 Gy of {sup 60}Co doses. (author)

  3. Effect of ethanolic extract of propolis on cell viability of chinese hamster ovary cells (CHO-K1) irradiated with {sup 60}CO gamma-rays using differential staining technique

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Marcos P.M. de; Castro, Renato F. de; Okazaki, Kayo; Vieira, Daniel P., E-mail: dpvieira@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    The objective of present study was to assess the effect of Brazilian propolis (AF-08) on CHO-K1 cells irradiated with {sup 60}Co, through the differential staining technique, using acridine orange and ethidium bromide. The cells were pre-incubated with different concentrations of propolis (50, 100 and 200 μg/mL) for 24h and irradiated with 5 Gy, analyzed at 24 and 48h after exposure. This technique is based on the cell capacity to incorporate fluorescent DNA dyes, where the viable (green), apoptotic (orange/yellow) and necrotic (red) cells can be identified through fluorescence microscopy. Digital high-resolution images were acquired from at least 5 visualization fields, and cells were analyzed using ImageJ and Flowing software. This approach permitted to analyze a large number of cells/sample with the time reduction, much easier and faster, proportioning more statistical power of the technique. The treatment with propolis only was not cytotoxic at 24 and 48h, except for the higher concentration of 200 μg/mL associated or not with radiation, increasing apoptotic and mainly necrotic cells (p<0.001). The data showed a promising use of propolis as well as technique used, pointing out that 200 μg/mL of propolis was cytotoxic, but at lower one (50 μg/mL) presented a radioprotective effect in irradiated CHO-K1 cells. (author)

  4. Characterization on the microstructure of gamma-ray irradiated Nd2Fe14B magnet.

    Science.gov (United States)

    Han, Young Chul; Kim, Young Hwan; Cha, Hyun Gil; Kim, Chang Woo; Ji, Eun Sun; Heo, Jin Kook; Kwon, Hae Woong; Kang, Young Soo

    2009-02-01

    The effect of 60Co gamma-ray irradiation on the microstructure of Nd2Fe14B magnets was investigated with electron spin resonance (ESR) and thermal mechanical analyzer (TMA). When the 60Co gamma-ray with dose from 0 Mrad to 100 Mrad was exposed to Nd2Fel,4B magnet having different sizes at room temperature, the increased demagnetization properties of the Nd2Fe14B magnets were studied by Hall probe. For all samples, changed Curie temperature and micro-crystal structure of Nd2Fe14B magnet by gamma-ray irradiation has been also studied. Moreover the strong and broad single line shaped ESR signal in the resonance magnetic field is attributed to unpaired electron of iron ions in the sample by the effect of gamma-ray irradiation.

  5. Thermoluminescence of Simulated Interstellar Matter after Gamma-ray Irradiation

    CERN Document Server

    Koike, K; Koike, C; Okada, M; Chihara, H

    2002-01-01

    Interstellar matter is known to be strongly irradiated by radiation and several types of cosmic ray particles. Simulated interstellar matter, such as forsterite $\\rm Mg_{2}SiO_{4}$, enstatite $\\rm MgSiO_{3}$ and magnesite $\\rm MgCO_{3}$ has been irradiated with the $\\rm ^{60}Co$ gamma-rays in liquid nitrogen, and also irradiated with fast neutrons at 10 K and 70 K by making use of the low-temperature irradiation facility of Kyoto University Reactor (KUR-LTL. Maximum fast neutron dose is $10^{17}n_f{\\rm /cm^{2}}$). After irradiation, samples are stored in liquid nitrogen for several months to allow the decay of induced radioactivity. We measured the luminescence spectra of the gamma ray irradiated samples during warming to 370K using a spectrophotometer. For the forsterite and magnesite, the spectra exhibit a rather intense peak at about 645 -- 655 nm and 660 nm respectively, whereas luminescence scarcely appeared in olivine sample. The spectra of forsterite is very similar to the ERE of the Red Rectangle.

  6. Resveratrol Effects on Life Span and Fertility of Caenorhabditis Elegans Subject to 60Co Gamma Ray Irradiation%白藜芦醇对60Coγ射线照射线虫寿命和生殖的影响

    Institute of Scientific and Technical Information of China (English)

    叶侃; 季晨博; 郭锡熔; 古桂雄

    2011-01-01

    Caenorhabditis elegans was used as experimental model to investigate radiation effect of resveratol on caenorhabdities elegans irradiated by 60Co γray. Treatment with resveratrol can increase average life span and spawning rate, improve the surrival rate of eggs, and protect their mitochondrion function of cacnorhabdities elegans exposure to 60Co rr ray. The results indicate that resveratrol has radiation protection effects, which might be related to its action on ROS decrease and mitochondrial defend.%以线虫作为实验模型,观察白藜芦醇(RES)对受60Coγ射线照射线虫的保护作用.结果表明,白藜芦醇能提高受照射线虫的寿命,增加产卵率,提高卵的存活率,保护其线粒体功能.其作用机制可能与白藜芦醇减轻氧自由基所致的线虫线粒体损伤有关.

  7. Effects of {sup 60}Co gamma-rays, ultraviolet light, and mitomycin C on halobacterium salinarium and thiobacillus intermedius

    Energy Technology Data Exchange (ETDEWEB)

    Shahmohammadi, H.R.; Asgarani, E.; Terato, Hiroaki; Ide, Hiroshi; Yamamoto, Osamu [Hiroshima Univ. (Japan)

    1997-03-01

    Lethal effects of {sup 60}Co {gamma}-rays, UV light, and mitomycin C on two kinds of bacteria, Halobacterium salinarium which grows in highly concentrated salt media and Thiobacillus intermedius which requires reduced sulfur compounds, were studied and compared with those on Escherichia coli B/r. D{sub 37} values for H. salinarium, T. intermedius and E. coli B/r were 393, 150, and 92 Gy, respectively, by exposure to {sup 60}Co {gamma}-rays. They were 212, 38, and 10 J/m{sup 2}, respectively, by exposure to UV light and 2.36, 0.25, and 0.53 {mu}g/ml/h, respectively, by exposure to mitomycin C. Against these agents, H salinarium was much more resistant than T. intermedius and E. coli B/r. (author)

  8. Effects of 60Co gamma-rays, ultraviolet light, and mitomycin C on Halobacterium salinarium and Thiobacillus intermedius.

    Science.gov (United States)

    Shahmohammadi, H R; Asgarani, E; Terato, H; Ide, H; Yamamoto, O

    1997-03-01

    Lethal effects of 60Co gamma-rays, UV light, and mitomycin C on two kinds of bacteria, Halobacterium salinarium which grows in highly concentrated salt media and Thiobacillus intermedius which requires reduced sulfur compounds, were studied and compared with those on Escherichia coli B/r. D37 values for H. salinarium, T. intermedius and E. coli B/r were 393, 150, and 92 Gy, respectively, by exposure to 60Co gamma-rays. They were 212, 38, and 10 J/m2, respectively, by exposure to UV light and 2.36, 0.25, and 0.53 microgram/ml/h, respectively, by exposure to mitomycin C. Against these agents, H. salinarium was much more resistant than T. intermedius and E. coli B/r.

  9. 60Coγ射线对生理盐水和玉米中黄曲霉孢子的辐照效应研究%Irradiation effect of 60Co gamma ray on Aspergillus flavus spores in normal saline and maize

    Institute of Scientific and Technical Information of China (English)

    钟凯; 高翔; 计融

    2011-01-01

    目的 研究γ射线对黄曲霉孢子辐照效应.方法 两种介质中不同浓度黄曲霉孢子经不同剂量辐照后进行菌落计数,计算D值和理论最小杀灭剂量,并实验验证实际最小杀灭剂量.结果 生理盐水中高浓度孢子D值0.39kGy,最低杀灭剂量2.5kGy,低浓度孢子D值0.47kGy,最低杀灭剂量1.5kGy;玉米中高浓度孢子D值为0.67kGy,最低杀灭剂量3.0kGy,低浓度孢子D值为0.72kGy,最低杀灭剂量2.0kGy.结论 3.0kGy可用于粮食中黄曲霉的杀灭.%Objective To observe irradiation effect of gamma ray on Aspergillus flavus spores.Methods Aspergillus flavus spores of different concentration were prepared on two media and were exposed to gamma ray.D10 values and theoretical minimal sterilizing doses were calculated by colony counting results.Actual minimal sterilizing doses were verified according to theoretical dose.Results D10 value and minimal sterilizing dose of high concentration spore in normal saline were 0.39kGy and 2.5kGy.Those of low concentration spore in normal saline were 0.47kGy and 1.5kGy.D10 value and minimal sterilizing dose of high concentration spore in maize were 0.67kGy and 3.0kGy.Those of low concentration spore in maize were 0.72kGy and 2.0kGy.Conclusion 3.0kGy may be suitable for grain processing to sterilize Aspergillus flavus.

  10. Activity evaluation from different native or irradiated with {sup 60} Co gamma rays snake venoms and their inhibitory effect on Leishmania (Leishmania) amazonensis; Avaliacao da atividade de diferentes venenos de serpentes, nativos ou irradiados, com radiacao gama de {sup 60} Co, quanto ao poder inibitorio do crescimento de Leishmania (Leishmania) amazonensis

    Energy Technology Data Exchange (ETDEWEB)

    Lourenco, Cecilia de Oliveira

    2000-07-01

    Cutaneous leishmaniasis is a disease, caused by Leishmania parasites, that occurs frequently in tropical and sub-tropical regions of the world. Skin lesions that could results in disfiguring aspect characterize it. The treatment is based on few drugs as antimony salts or pentamidine that are toxic with increasing resistance by the parasite. Alternative forms of disease treatment are in constant search, including natural components as snake venoms. Previous studies demonstrate that some components of snake venoms have an inhibitory effect against those parasites, including Leishmania species. Although snake venoms presented high toxicity, several methods have been described to detoxify most or some of their toxic components, with favorable results by the use of gamma irradiation. In this report we tested several native and irradiated snake venoms for inhibitory effect against Leishmania (Leishmania) amazonensis parasite and LLCMK{sub 2} mammalian cells, with enzymatic tests and electrophoresis. There are significant activity in Acanthophis antarcticus, Agkistrodon bilineatus, Bothrops moojeni, Bothrops jararaca, Hoplocephalus stephensi, Naja melanoleuca, Naja mossambica, Pseudechis australis, Pseudechis colletti, Pseudechis guttatus and Pseudechis porphyriacus, venom being inactive Pseudonaja textilis, Notechis ater niger, Notechis scutatus. Oxyuranus microlepidotus and Oxyuranus scutellatus venoms. After 2 KGy of {sup 60}Co irradiation most venom loses significantly their activity. Venoms with antileishmanial activity presented L-amino acid oxidase (L-AO) activity and showed common protein with a molecular weight about 60kDa in SDS-PAGE. These results indicate that L-AO activity in those venoms are probably related with antileishmanial effect. (author)

  11. Gamma-ray spectroscopy on irradiated fuel rods

    Energy Technology Data Exchange (ETDEWEB)

    Terremoto, Luis Antonio Albiac [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro de Engenharia Nuclear], e-mail: laaterre@ipen.br

    2009-07-01

    The recording of gamma-ray spectra along an irradiated fuel rod allows the fission products to be qualitatively and quantitatively examined. Among all nondestructive examinations performed on irradiated fuel rods by gamma-ray spectroscopy, the most comprehensive one is the average burnup measurement, which is quantitative. Moreover, burnup measurements by means of gamma-ray spectroscopy are less time-consuming and waste-generating than burnup measurements by radiochemical, destructive methods. This work presents the theoretical foundations and experimental techniques necessary to measure, using nondestructive gamma-ray spectroscopy, the average burnup of irradiated fuel rods in a laboratory equipped with hot cells. (author)

  12. Gamma-ray Irradiation Induces Useful Morphological Variation in Bermudagrass

    Directory of Open Access Journals (Sweden)

    Songul SEVER MUTLU

    2015-12-01

    Full Text Available Bermudagrass, Cynodon dactylon (L. Pers. is a widely used warm-season turfgrass species in warmer regions of the world. Gamma (ɣ irradiation has been used to generate useful variations in turfgrass breeding for various morphological traits. The objective of the present study was to measure and determine variations in morphology and turfgrass characteristics of a native drought resistant bermudagrass germplasm irradiated with 70, 90 or 110 Gy using a 60Co source. The stolons containing a single node were irradiated and immediately planted for regeneration in a greenhouse at the Akdeniz University, Antalya, Turkey. Selected mutants regenerated from the irradiated stolons were clonally propagated and transplanted into plastic pots for further observations of turfgrass characteristics.  Survival rates of stolons exposed to 70, 90 and 110 Gy were 76%, 43% and 17% respectively, 6 weeks after treatment. Dosages of 85 and 57 Gy were determined as LD50 and LD20 for the cuttings, respectively. The linear reduction of survival rate with increasing gamma-rays was highly correlated (r2=0.99. A total of four mutant lines (0.3 % of the irradiated plants showed a distinct dwarfed growth habit. Three of these lines were originated from 70 Gy and one from 110 Gy. These mutant lines exhibited more dwarf growth habit, higher shoot density, finer leaf texture than parental genotype. Mutant lines developed in this study can be used for the development of improved bermudagrass cultivars for landscaping and sports turf.

  13. Comparative effects of 60Co gamma-rays and neon and helium ions on cycle duration and division probability of EMT 6 cells. A time-lapse cinematography study.

    Science.gov (United States)

    Collyn-d'Hooghe, M; Hemon, D; Gilet, R; Curtis, S B; Valleron, A J; Malaise, E P

    1981-03-01

    Exponentially growing cultures of EMT 6 cells were irradiated in vitro with neon ions, helium ions or 60Co gamma-rays. Time-lapse cinematography allowed the determination, for individual cells, of cycle duration, success of the mitotic division and the age of the cell at the moment of irradiation. Irradiation induced a significant mitotic delay increasing proportionally with the delivered dose. Using mitotic delay as an endpoint, the r.b.e. for neon ions with respect to 60Co gamma-rays was 3.3 +/- 0.2 while for helium ions it was 1.2 +/- 0.1. Mitotic delay was greatest in those cells that had progressed furthest in their cycle at the time of irradiation. No significant mitotic delay was observed in the post-irradiation generation. Division probability was significantly reduced by irradiation both in the irradiated and in the post-irradiated generation. The reduction in division probability obtained with 3 Gy of neon ions was similar to that obtained after irradiation with 6 Gy of helium ions or 60Co gamma-rays.

  14. Development of irradiator {sup 60}Co sources

    Energy Technology Data Exchange (ETDEWEB)

    Mosca, Rodrigo C.; Moura, Eduardo S.; Zeituni, Carlos A.; Mathor, Monica B., E-mail: rcmosca@usp.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    According to a recent report by the International Agency for Research on Cancer (IARC) / WHO (2008-2010), the global impact of cancer more than doubled in 30 years. In this report, it was estimated that occurred about 12 million new cancer cases and 7 million deaths. In Brazil in 2010, with estimates for the year 2011, point to the occurrence of 489,270 new cases of cancer. Among the possibilities for cancer treatment, radiotherapy is one of the most important therapeutic and resources used to combat it. However, inherent complications of treatment can occur such as tiredness, loss of appetite, radiodermatitis and in more extreme cases late radionecrosis. In order to reproduce a point of radionecrosis in the vicinity of radiodermatitis to mimic these effects in animals, producing a model for assessment of tissue repair, we propose the setting up of an irradiator source of collimated {sup 60}Co. The development of was based on 11 sources of {sup 60}Co with 1 mm thickness that were inserted by inference in stainless steel 'gate-source' screw (patent pending) and later adjusted in a cross-shaped arrangement reinforced so that the beam radiation is directed to a target point, saving for other regions around this target point. The main use of this irradiator with sources of {sup 60}Co is just one cause radionecrosis point (target point) of approximately 5 mm{sup 2} with a surrounding and adjacent area of radiodermatitis around about 8 to 10 mm{sup 2} in laboratory animals for subsequent coating with epidermal-dermal matrix populated by a cell culture of human fibroblasts, keratinocytes and mesenchymal stem cells. With that said, its use will be valuable for evaluation of curative treatments against the bone and radionecrosis or palliative treatment rather than as it is currently assumed. (author)

  15. The depth-dependence of the biological effectiveness of 60Co gamma rays in a large absorber determined by dicentric chromosomes in human lymphocytes.

    Science.gov (United States)

    Schmid, Ernst; Roos, Hartmut; Kramer, Hans-Michael

    2008-01-01

    Radiobiological evidence is shown concerning a significant depth-dependence of the maximum relative biological effectiveness at limiting low doses (RBE(M)) of (60)Co gamma rays in a cubic polymethylmethacrylate (PMMA) phantom of 30 cm edge length. Using the dose-response curve for the dicentric data in human lymphocytes obtained in the present experiment at a depth of 20 cm, together with the comprehensive and consistent data set determined earlier at smaller depths of the PMMA phantom, there is an increase in the RBE(M) value by a factor of 2.18 +/- 1.25 at a depth of 20 cm relative to 1 cm in the phantom. All the dicentric data are based on identical exposure durations and irradiation temperatures as well as identical culture and evaluation conditions, with blood from the same donor.

  16. An investigation on the radiation sensitivity of DNA conformations to {sup 60}Co gamma rays by using Geant4 toolkit

    Energy Technology Data Exchange (ETDEWEB)

    Semsarha, F. [Institute of Biochemistry and Biophysics (IBB), University of Tehran, P.O. Box 13145-1384, Tehran (Iran, Islamic Republic of); Goliaei, B., E-mail: goliaei@ibb.ut.ac.ir [Institute of Biochemistry and Biophysics (IBB), University of Tehran, P.O. Box 13145-1384, Tehran (Iran, Islamic Republic of); Raisali, G.; Khalafi, H. [Radiation Applications Research School, Nuclear Science and Technology Research Institute, P.O. Box 11365-3486, Tehran (Iran, Islamic Republic of); Mirzakhanian, L. [Medical Physics Unit, McGill University, 1650 Cedar Avenue, Montreal, Quebec (Canada)

    2014-03-15

    To investigate the impact of conformational properties of genetic material of living cells on radiation-induced DNA damage, single strand breaks (SSB), double strand breaks (DSB) and some microdosimetric quantities of A, B and Z-DNA conformations caused by {sup 60}Co gamma rays, have been calculated. Based on a previous B-DNA geometrical model, models of A and Z forms have been developed. Simple 34 base pairs segments of each model repeated in high number and secondary electron spectrum of {sup 60}Co gamma rays have been simulated in a volume of a typical animal cell nucleus. All simulations in this study have been performed by using the Geant4 (GEometry ANd Tracking 4)-DNA extension of the Geant4 toolkit. The results showed that, B-DNA has the lowest yield of simple strand breaks with 2.23 × 10{sup −10} Gy{sup −1} Da{sup −1} and 1.0 × 10{sup −11} Gy{sup −1} Da{sup −1} for the SSB and DSB damage yield, respectively. The A-DNA has the highest SSB yield with 3.59 × 10{sup −10} Gy{sup −1} Da{sup −1} and the Z-DNA has the highest DSB yields with 1.8 × 10{sup −11} Gy{sup −1} Da{sup −1}. It has been concluded that there is a direct correlation between the hit probability, mean specific imparted energy and SSB yield in each model of DNA. Moreover, there is a direct correlation between the DSB yield and both the mean lineal energy and topological characteristics of each model.

  17. Sensitivity of P-Channel MOSFET to X- and Gamma-Ray Irradiation

    Directory of Open Access Journals (Sweden)

    Milić Pejović

    2013-01-01

    Full Text Available Investigation of Al-gate p-channel MOSFETs sensitivity following irradiation using 200 and 280 kV X-ray beams as well as gamma-ray irradiation of 60Co in the dose range from 1 to 5 Gy was performed in this paper. The response followed on the basis of threshold voltage shift and was studied as a function of absorbed dose. It was shown that the most significant change in threshold voltage was in the case of MOSFET irradiation in X-ray fields of 200 kV and when the gate voltage was +5 V. For practical applications in dosimetry, the sensitivity of the investigated MOSFETs was also satisfactory for X-ray tube voltage of 280 kV and for gamma rays. Possible processes in gate oxide caused by radiation and its impact on the response of MOSFETs were also analyzed in this paper.

  18. 60Coγ射线2.0 Gy剂量诱导大鼠淋巴细胞基因表达的改变%Study of Differential Gene Expression Profiling in Peripheral Blood Lymphocyte of Rat with 2 .0 Gy Gamma Ray Irradiation

    Institute of Scientific and Technical Information of China (English)

    李建国; 尹晶晶; 秦秀军; 张伟; 周晋源; 闻建华

    2013-01-01

    利用Agilent Rat全基因组芯片技术和实时荧光定量PCR技术,采用60 Coγ射线对SD大鼠全身照射,照射剂量为2.0 Gy ,分析照后6、12、24小时大鼠外周血淋巴细胞的差异表达基因谱和通路,同时对基因芯片结果进行验证。结果表明:(1)照后6小时,差异表达基因有1084个,其中上调的736个,下调的348个;照后12小时,差异表达基因有2590个,其中上调的1621个,下调的969个;照后24小时,差异表达基因有3938个,其中上调的2278个,下调的1660个;3个时间点共同差异表达基因有446个,其中上调的274个,下调的172个。(2)照后6小时,差异表达基因涉及到的通路有18个;照后12小时,差异表达基因涉及到的通路有35个;照后24小时,差异表达基因涉及到的通路有38个。其中通路Cell adhesion molecules、Toxoplasmosis、B cell receptor signaling、Intestinal immune network for IgA Production等在照后3个时间点均有出现。(3)差异表达基因Trmt61a和Enc1的相对定量结果与基因芯片检验结果表达趋势一致。%The study analyzed the differential expression profile and pathway of peripheral blood lymphocyte in SD rats 6 ,12 and 24 hours after irradiation to 2 .0 Gy gamma ray .The results showed that at 6 hours after ir-radiation there were 1084 differentially expressed genes of which 736 genes were up-regulated and 348 genes down-regulated .12 hours after irradiation there were 2590 differentially expressed genes of which 1621 genes were up-regulated and 969 genes down-regulated .24 hours after irradiation there were 3938 differentially ex-pressed genes of which 2278 genes were up-regulated and 1660 genes down-regulated .There were 446 co-ex-pressed differential genes at three time points ,of which 274 genes were up-regulated and 172 genes down-regu-lated .The KEGG analysis revealed that 6h point 18 pathways ,12 hours point 35 pathways ,and 24 hours point

  19. Protection of negative gravitaxis in Euglena gracilis Z against gamma-ray irradiation by Trolox C

    Energy Technology Data Exchange (ETDEWEB)

    Sakashita, Tetsuya; Doi, Masahiro; Yasuda, Hiroshi; Fuma, Shoichi [National Inst. of Radiological Sciences, Chiba (Japan). Research Center for Radiation Safety; Hader, D.P. [Biologie der Friedrich-Alexander Univ., Erlangen (Germany). Inst. fuer Botanik und Pharmazeutische Biologie

    2002-12-01

    The protective effects of Trolox on the inhibition of negative gravitaxis in Euglena gracilis exposed to 200 Gy {sup 60}Co gamma-rays were examined using different concentrations (1, 10 and 100 {mu}M). The orientation precision of the negative gravitaxis was quantified using the r-value. A significant decrease in the r-value was observed in gamma-irradiated samples (0.18+/-0.03) compared to those of non-irradiated samples (0.47+/-0.03). There were no significant changes in the r-value of cells exposed to 200 Gy gamma-rays by the addition of 1 or 10 {mu}M of Trolox. A significant increase (0.19) in the r-value of cells exposed to 200 Gy with 100 {mu}M Trolox was observed. The results indicates that Trolox at a concentration of 100 {mu}M protects negative gravitaxis against {sup 60}Co gamma-ray irradiation at a dose of 200 Gy. It also suggests that the negative gravitaxis of Euglena gracilis is affected by free radicals.(author)

  20. Gamma-ray irradiation tests of CMOS sensors used in imaging techniques

    Directory of Open Access Journals (Sweden)

    Cappello Salvatore G.

    2014-01-01

    Full Text Available Technologically-enhanced electronic image sensors are used in various fields as diagnostic techniques in medicine or space applications. In the latter case the devices can be exposed to intense radiation fluxes over time which may impair the functioning of the same equipment. In this paper we report the results of gamma-ray irradiation tests on CMOS image sensors simulating the space radiation over a long time period. Gamma-ray irradiation tests were carried out by means of IGS-3 gamma irradiation facility of Palermo University, based on 60Co sources with different activities. To reduce the dose rate and realize a narrow gamma-ray beam, a lead-collimation system was purposely built. It permits to have dose rate values less than 10 mGy/s and to irradiate CMOS Image Sensors during operation. The total ionizing dose to CMOS image sensors was monitored in-situ, during irradiation, up to 1000 Gy and images were acquired every 25 Gy. At the end of the tests, the sensors continued to operate despite a background noise and some pixels were completely saturated. These effects, however, involve isolated pixels and therefore, should not affect the image quality.

  1. Effects of gamma-ray and high energy carbon ion irradiation on swimming velocity of Euglena gracilis

    Science.gov (United States)

    Sakashita, T.; Doi, M.; Yasuda, H.; Fuma, S.; Häder, D.-P.

    The effects of gamma-ray and high energy carbon ion irradiation on the swimming velocity of the photosynthetic flagellate Euglena gracilis strain Z were studied, focusing on a dose-effect relationship. Cells were exposed to 60Co gamma-rays at 6 doses of 10, 15, 20, 40, 100 and 200 Gy for water, and also to 290 MeV/amu carbon ions from the Heavy Ion Medical Accelerator in Chiba at 7 doses (5, 10, 15, 20, 50, 100 and 200 Gy for water). The swimming velocity was measured by a biomonitoring system, called ECOTOX. The swimming velocities of Euglena gracilis cells were significantly decreased by >40 Gy gamma-rays and >5 Gy carbon ions, respectively. The 50% effective doses for inhibition, 34±4 Gy (gamma-rays) and 13±1 Gy (290 MeV/amu carbon ions), were estimated from the best fit to data of the logistic model. The relative biological effectiveness (2.6±0.4) was calculated by the ratio of 50% effective doses. The inhibition of the swimming velocity of the cells irradiated with gamma-rays was still present after 3 days, while recovery of the swimming velocity was shown in the cells exposed to 290 MeV/amu carbon ions. It is suggested that ionizing radiation inhibits ATP production and/or increases frictional drag on beating of the flagellum, thus decreasing swimming velocity.

  2. (60)Co in cast steel matrix: A European interlaboratory comparison for the characterisation of new activity standards for calibration of gamma-ray spectrometers in metallurgy.

    Science.gov (United States)

    Tzika, Faidra; Burda, Oleksiy; Hult, Mikael; Arnold, Dirk; Marroyo, Belén Caro; Dryák, Pavel; Fazio, Aldo; Ferreux, Laurent; García-Toraño, Eduardo; Javornik, Andrej; Klemola, Seppo; Luca, Aurelian; Moser, Hannah; Nečemer, Marijan; Peyrés, Virginia; Reis, Mario; Silva, Lidia; Šolc, Jaroslav; Svec, Anton; Tyminski, Zbigniew; Vodenik, Branko; Wätjen, Uwe

    2016-08-01

    Two series of activity standards of (60)Co in cast steel matrix, developed for the calibration of gamma-ray spectrometry systems in the metallurgical sector, were characterised using a European interlaboratory comparison among twelve National Metrology Institutes and one international organisation. The first standard, consisting of 14 disc shaped samples, was cast from steel contaminated during production ("originally"), and the second, consisting of 15 similar discs, from artificially-contaminated ("spiked") steel. The reference activity concentrations of (60)Co in the cast steel standards were (1.077±0.019) Bqg(-1) on 1 January 2013 12h00 UT and (1.483±0.022) Bqg(-1) on 1 June 2013 12h00 UT, respectively.

  3. Calculation of direct effects of {sup 60}Co gamma rays on the different DNA structural levels: A simulation study using the Geant4-DNA toolkit

    Energy Technology Data Exchange (ETDEWEB)

    Tajik, Marjan; Rozatian, Amir S.H. [Department of Physics, University of Isfahan, Hezar Jarib Street, Isfahan 81746-73441 (Iran, Islamic Republic of); Semsarha, Farid, E-mail: Semsarha@ibb.ut.ac.ir [Institute of Biochemistry and Biophysics (IBB), University of Tehran, P.O. Box: 13145-1384, Tehran (Iran, Islamic Republic of)

    2015-03-01

    In this study, simple single strand breaks (SSB) and double strand breaks (DSB) due to direct effects of the secondary electron spectrum of {sup 60}Co gamma rays on different organizational levels of a volume model of the B-DNA conformation have been calculated using the Geant4-DNA toolkit. Result of this study for the direct DSB yield shows a good agreement with other theoretical and experimental results obtained by both photons and their secondary electrons; however, in the case of SSB a noticeable difference can be observed. Moreover, regarding the almost constant yields of the direct strand breaks in the different structural levels of the DNA, calculated in this work, and compared with some theoretical studies, it can be deduced that the direct strand breaks yields depend mainly on the primary double helix structure of the DNA and the higher-order structures cannot have a noticeable effect on the direct DNA damage inductions by {sup 60}Co gamma rays. In contrast, a direct dependency between the direct SSB and DSB yields and the volume of the DNA structure has been found. Also, a further study on the histone proteins showed that they can play an important role in the trapping of low energy electrons without any significant effect on the direct DNA strand breaks inductions, at least in the range of energies used in the current study.

  4. Free ion yield observed in liquid isooctane irradiated by gamma rays. Comparison with the Onsager theory.

    Science.gov (United States)

    Pardo, J; Franco, L; Gómez, F; Iglesias, A; Lobato, R; Mosquera, J; Pazos, A; Pena, J; Pombar, M; Rodríguez, A; Sendón, J

    2004-05-21

    We have analysed data on the free ion yield observed in liquid isooctane irradiated by 60Co gamma rays within the framework of the Onsager theory about initial recombination. Several distribution functions describing the electron thermalization distance have been used and compared with the experimental results: a delta function, a Gaussian-type function and an exponential function. A linear dependence between the free ion yield and the external electric field has been found at low-electric-field values (E < or = 1.2 x 10(3) V mm(-1)) in excellent agreement with the Onsager theory. At higher electric field values, we obtain a solution in power series of the external field using the Onsager theory.

  5. Free ion yield observed in liquid isooctane irradiated by {gamma} rays. Comparison with the Onsager theory

    Energy Technology Data Exchange (ETDEWEB)

    Pardo, J [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Franco, L [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Gomez, F [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Iglesias, A [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Lobato, R [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain); Mosquera, J [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain); Pazos, A [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Pena, J [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Pombar, M [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain); RodrIguez, A [Departamento de FIsica de PartIculas, Facultade de FIsica, 15782 Santiago de Compostela (Spain); Sendon, J [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain)

    2004-05-21

    We have analysed data on the free ion yield observed in liquid isooctane irradiated by {sup 60}Co {gamma} rays within the framework of the Onsager theory about initial recombination. Several distribution functions describing the electron thermalization distance have been used and compared with the experimental results: a delta function, a Gaussian-type function and an exponential function. A linear dependence between the free ion yield and the external electric field has been found at low-electric-field values (E {<=} 1.2 x 10{sup 3} V mm{sup -1}) in excellent agreement with the Onsager theory. At higher electric field values, we obtain a solution in power series of the external field using the Onsager theory.

  6. Gamma-ray spectroscopy on irradiated MTR fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Terremoto, L.A.A. E-mail: laaterre@net.ipen.br; Zeituni, C.A.; Perrotta, J.A.; Silva, J.E.R. da

    2000-08-11

    The availability of burnup data is an important requirement in any systematic approach to the enhancement of safety, economics and performance of a nuclear research reactor. This work presents the theory and experimental techniques applied to determine, by means of nondestructive gamma-ray spectroscopy, the burnup of Material Testing Reactor (MTR) fuel elements irradiated in the IEA-R1 research reactor. Burnup measurements, based on analysis of spectra that result from collimation and detection of gamma-rays emitted in the decay of radioactive fission products, were performed at the reactor pool area. The measuring system consists of a high-purity germanium (HPGe) detector together with suitable fast electronics and an on-line microcomputer data acquisition module. In order to achieve absolute burnup values, the detection set (collimator tube+HPGe detector) was previously calibrated in efficiency. The obtained burnup values are compared with ones provided by reactor physics calculations, for three kinds of MTR fuel elements with different cooling times, initial enrichment grades and total number of fuel plates. Both values show good agreement within the experimental error limits.

  7. Comparative nephrotoxicity of native or Co-60 gamma rays irradiated crotoxin in mice

    Energy Technology Data Exchange (ETDEWEB)

    Rocha, Andre Moreira; Alves, Glaucie J.; Aires, Raquel da Silva; Turibio, Thompson O.; Thomazi, Gabriela O. Coelho; Spencer, Patrick J.; Nascimento, Nanci do, E-mail: andrerocha@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Nascimento-Rocha, Josefa M.; Magalhaes Filho, Asterio Souza, E-mail: 0304@prof.itpacporto.com.br [Instituto Tocantinense Presidente Antonio Carlos Porto (ITPAC), Porto Nacional, TO (Brazil)

    2015-07-01

    Snake venoms are complex mixtures of proteins and peptides with a wide spectrum of physiological targets such as the blood coagulation and cardiovascular systems and the motor end plate among others. Acute renal failure is a common complication in accidents with the South American rattlesnake. The toxin involved in this pathology is the crotoxin, a major component of the venom in terms of concentration and toxicity. Snake venoms, when irradiated with {sup 60}Co gamma rays present a significant decrease in toxicity while the immunogenic properties of its components are preserved. The use of irradiated venom is an attractive alternative for antisera production since it might reduce the appearance of renal lesions improving the welfare and lifespan of those animals employed on antivenom production. At the present work, we have compared the effects of native and irradiated crotoxin on the mice renal function. Tubular lesions were observed in all the samples from the animal group injected with native crotoxin. Animals injected with the irradiated toxin presented alteration only after 30 minutes and 1 hour after injection. These data suggest that the onset of the renal lesions is delayed and that the severity of the lesions might be lower when using irradiated crotoxin. (author)

  8. The RBE of 3.4 MeV alpha-particles and 0.565 MeV neutrons relative to 60Co gamma-rays for neoplastic transformation of human hybrid cells and the impact of culture conditions.

    Science.gov (United States)

    Frankenberg-Schwager, M; Spieren, S; Pralle, E; Giesen, U; Brede, H J; Thiemig, M; Frankenberg, D

    2010-01-01

    The neoplastic transformation of human hybrid CGL1 cells is affected by perturbations from external influences such as serum batch and concentration, the number of medium changes during the 21-day expression period and cell seeding density. Nevertheless, for doses up to 1.5 Gy, published transformation frequencies for low linear energy transfer (LET) radiations (gamma-rays, MeV electrons or photons) are in good agreement, whereas for higher doses larger variations are reported. The (60)Co gamma-ray data here for doses up to 1.5 Gy, using a low-yield serum batch and only one medium change, are in agreement with published frequencies of neoplastic transformation of human hybrid cells. For 3.4 MeV alpha-particles (LET = 124 keV/mum) and 0.565 MeV monoenergetic neutrons relative to low doses of (60)Co gamma-rays, a maximum relative biological effectiveness (RBE(M)) of 2.8 +/- 0.2 and 1.5 +/- 0.2, respectively, was calculated. Surprisingly, at higher doses of (60)Co gamma-rays lower frequencies of neoplastic transformation were observed. This non-monotonic dose relationship for neoplastic transformation by (60)Co gamma-rays is likely due to the lack of a G2/M arrest observed at low doses resulting in higher transformation frequencies per dose, whereas the lower frequencies per dose observed for higher doses are likely related to the induction of a G2/M arrest.

  9. The influence of low temperature on gamma-ray irradiated permanent magnets.

    Science.gov (United States)

    Han, Young Chul; Cha, Hyun Gil; Kim, Chang Woo; Ji, Eun Sun; Kim, Young Hwan; Kang, Dong In; Kang, Young Soo

    2009-12-01

    The temperature effect on the magnetic property of gamma-ray irradiated Nd-Fe-B and Sr-Ferrite magnets has been investigated. When the permanent magnets are exposed to gamma-ray, it's magnetic and other related properties are declined with degree of dose. The decreased magnetic property by gamma-ray irradiation at low temperature is similar with the result of magnet at high temperature. The temperature effect on the gamma-ray irradiation at exposed moment is also regarded as one of the important parameters for the reduced magnetic properties. The gamma-irradiation at low temperature was carried out at 195 K, and the changed properties of two kinds of magnets before and after gamma-irradiation were comparatively studied. The increased demagnetization of the magnets were studied by Hall probe. And changed Curie temperature and micro-crystal structure of each permanent magnet by gamma-ray irradiation has been also studied. Moreover the strong and broad single line shape of ESR signal in the resonance magnetic field is attributed to unpaired electron of Fe2+ in the sample by the effect of gamma-ray irradiation.

  10. Thermal, tensile and rheological properties of high density polyethylene (HDPE) processed and irradiated by gamma-ray in different atmospheres

    Energy Technology Data Exchange (ETDEWEB)

    Ferreto, H. F. R., E-mail: hferreto@ipen.br, E-mail: ana-feitoza@yahoo.com.br; Oliveira, A. C. F., E-mail: hferreto@ipen.br, E-mail: ana-feitoza@yahoo.com.br; Parra, D. F., E-mail: dfparra@ipen.br, E-mail: ablugao@ipen.br; Lugão, A. B., E-mail: dfparra@ipen.br, E-mail: ablugao@ipen.br [Center of Chemistry and Environment, Institute of Energy and Nuclear Research - IPEN (Brazil); Gaia, R., E-mail: renan-gaia7@hotmail.com [Faculdades Oswaldo Cruz (Brazil)

    2014-05-15

    The aim of this paper is to investigate structural changes of high density polyethylene (HDPE) modified by ionizing radiation (gamma rays) in different atmospheres. The gamma radiation process for modification of commercial polymers is a widely applied technique to promote new physical-chemical and mechanical properties. Gamma irradiation originates free radicals which can induce chain scission or recombination, providing its annihilation, branching or crosslinking. This polymer was irradiated with gamma source of {sup 60}Co at doses of 5, 10, 20, 50 or 100 kGy at a dose rate of 5 kGy/h. The changes in molecular structure of HDPE, after gamma irradiations were evaluated using thermogravimetric analysis (TGA) and tensile machine and oscillatory rheology. The results showed the variations of the properties depending on the dose at each atmosphere.

  11. Thermal, tensile and rheological properties of high density polyethylene (HDPE) processed and irradiated by gamma-ray in different atmospheres

    Science.gov (United States)

    Ferreto, H. F. R.; Oliveira, A. C. F.; Gaia, R.; Parra, D. F.; Lugão, A. B.

    2014-05-01

    The aim of this paper is to investigate structural changes of high density polyethylene (HDPE) modified by ionizing radiation (gamma rays) in different atmospheres. The gamma radiation process for modification of commercial polymers is a widely applied technique to promote new physical-chemical and mechanical properties. Gamma irradiation originates free radicals which can induce chain scission or recombination, providing its annihilation, branching or crosslinking. This polymer was irradiated with gamma source of 60Co at doses of 5, 10, 20, 50 or 100 kGy at a dose rate of 5 kGy/h. The changes in molecular structure of HDPE, after gamma irradiations were evaluated using thermogravimetric analysis (TGA) and tensile machine and oscillatory rheology. The results showed the variations of the properties depending on the dose at each atmosphere.

  12. Modifications in structural, cation distribution and magnetic properties of {sup 60}Co gamma irradiated Li-ferrite

    Energy Technology Data Exchange (ETDEWEB)

    Mane, Maheshkumar L. [Department of Physics, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.) 431 004 (India); Shirsath, Sagar E., E-mail: shirsathsagar@hotmail.com [Department of Physics, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.) 431 004 (India); Dhage, Vinod N.; Jadhav, K.M. [Department of Physics, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.) 431 004 (India)

    2011-09-15

    Highlights: {yields} Gamma irradiation induced defects in lithium ferrite. {yields} Modifications in structural and magnetic properties. {yields} Fe{sup 3+} changes to Fe{sup 2+} after gamma irradiation. - Abstract: Polycrystalline samples of Li{sub 0.5}Fe{sub 2.5}O{sub 4} ferrite precursor were prepared by conventional standard double sintering ceramic technique and then irradiated with three different doses of {sup 60}Co gamma rays. The crystal structure and phase orientation of the irradiated and unirradiated samples of Li{sub 0.5}Fe{sub 2.5}O{sub 4} ferrite was done by using X-ray diffraction technique at room temperature. The lattice parameter of the studied samples increased due to the formation of Fe{sup 2+} ions under the ionizing effect of gamma radiation. The strain in the materials due to the irradiation was calculated from XRD data. Scanning electron microscope (SEM) studies indicate that the irradiation causes amorphization, especially at the grain boundaries. The cation distribution was calculated from XRD data analysis. By using cation distribution structural parameters such as theoretical lattice constant, ionic radii of available sites and the oxygen parameter 'u' have been calculated. The estimated cation distribution and other structural parameters shows strong influence of gamma rays on polycrystalline Li-ferrite. The magnetic properties of irradiated and unirradiated lithium ferrite were performed by using pulse field hysteresis loop technique at room temperature. Electrical properties such as diffusion coefficient and dielectric properties were carried out with the influence of gamma irradiation. Activation energy of diffusion process decreased after irradiation. The increase of diffusion coefficient with increasing dose rate of gamma irradiation was reinforced by the increase of Fe{sup 2+} ions and the displacement of metal ions from its original sites under the effect of gamma irradiation.

  13. Pagure {sup 60}Co panoramic irradiation facility; Pagure irradiateur panoramique au {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Puig, J.R.; Laizier, J.; Lorin, M.; Laroche, R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    After a description of the various parts of 'PAGURE', a 10 KCi panoramic irradiation facility, and of the operations data, a critic scrutiny is given. From the experience of five years operations, working of the facility can be thought of very satisfying. From the point of view of standardization of irradiation facilities, PAGURE can be taken, in its range, as a standard design. (authors) [French] Apres avoir decrit les differents elements constitutifs de 1'irradiateur panoramique de 10 KCi 'PAGURE' et precise les donnees d'exploitation, on en fait l'examen critique. A la lumiere de cinq annees d'utilisation, le fonctionnement de 1'irradiateur apparait extremement satisfaisant. Dans une perspective de standardisation des appareils, on peut, dans sa gamme, le considerer comme une realisation type. (auteurs)

  14. Study of recombination processes for 'electron-hole' pairs in germanium irradiated by {gamma} rays from {sup 60}Co using the photovoltaic effect in P-N junctions; Etude du processus de recombinaison des paires ''electron-trou'' dans le germanium irradie par les rayons {gamma} du cobalt 60 a l'aide de l'effet photovoltaique dans les jonctions P-N

    Energy Technology Data Exchange (ETDEWEB)

    Zahedi-Mochadam, A.A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-10-01

    Using the photo-voltaic effect in p-n junctions, we have studied, during bombardment, the mechanism of the recombination of 'electron-hole' pairs in the presence of structure defects produced in germanium of the N and P types by {gamma} rays from a Co{sup 60} source. At 310 K the level of the recombination centres is situated 0.25 eV above the conduction band and the capture cross-sections of the holes and of the electrons have the respective values of: {sigma}{sub p} = 4 X 10{sup -15} cm{sup 2} and {sigma}{sub n} = 3 X 10{sup -15} cm{sup 2}. The value of {sigma}{sub n} appears to be under-estimated because the number of defects in P-type samples appears to be lower than that in N-type samples. These results lead to the conclusion that the interstitials are responsible for the recombination. At 80 K it has been found that in N-type samples, a shallow level exists at O.05 eV below the conduction band with a capture cross-section for the holes of {sigma}{sub p} {>=} 10{sup -14} cm{sup 2}. We believe that in this case the recombination of charge carriers is controlled by the neighbouring 'defect-interstitial' pairs. In P-type samples at low temperature, the life-time is practically constant during irradiation. This fact is attributed to a spontaneous annealing of defects ol purely electrical origin. In the last part of the work the study of the photo-voltaic effect applied to the problem of gamma radiation dosimetry is considered. It is shown that such dosimeters, based on this principle, make it possible to measure the intensity of gamma rays over a very wide range. (author) [French] En utilisant l'effet photovoltaique dans les jonctions p-n, nous avons etudie au cours du bombardement le mecanisme de recombinaison des paires 'electron-trou' en presence des defauts de structure introduits dans le germanium de type N et de type P par les rayons gamma d'une source de Co{sup 60}. A 310 K, le niveau des centres de recombinaison se

  15. Livestock wastewater treatment by zeolite ion exchange and gamma-ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Ryul; Kim, Tak Hyun; Lee, Myun Joo [Radiation Research Center for Industry and Environment, Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2008-01-15

    Livestock wastewater containing high concentrations of organic matters and ammonia-nitrogen has been known as one of the recalcitrant wastewater. It is difficult to treat by conventional wastewater treatment techniques. This study was carried out to evaluate the feasibility of zeolite ion exchange and gamma-ray irradiation treatment of livestock wastewater. The removal efficiencies of SCOD{sub Cr} and NH3-N were significantly enhanced by gamma-ray irradiation after zeolite ion exchange as a pre-treatment. However, the effects of zeolite particle size on the SCOD{sub Cr} and NH{sub 3}-N removal efficiencies were insignificant. These results indicate that the combined process of zeolite ion exchange and gamma-ray irradiation has potential for the treatment of livestock wastewater.

  16. Humoral immune response against native or {sup 60}Co irradiated venom and mucus from stingray Paratrygon aiereba

    Energy Technology Data Exchange (ETDEWEB)

    Thomazi, Gabriela Ortega Coelho; Alves, Glaucie Jussilane; Aires, Raquel da Silva; Turibio, Thompson de Oliveira; Rocha, Andre Moreira; Spencer, Patrick Jack; Nascimento, Nanci do, E-mail: 0916@prof.itpacporto.com.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Seibert, Carla Simone, E-mail: carlaseibert@yahoo.com [Universidade Federal do Tocantins (UFT), Porto Nacional, TO (Brazil)

    2015-07-01

    Poisonings and traumas caused by poisonous freshwater fish such as rays are considered a major public health problem and draw attention because of accidents involving these animals cause serious local symptoms and are disabling, keeping the victim away from work. The therapy of these cases is based only on the symptoms of patients, which implies in its low efficiency, causing suffering for the victims. This study aims to evaluate and compare the humoral immune response in animals inoculated with native or {sup 60}Co irradiated Paratrygon aiereba venom and mucus. Ionizing radiation has proven to be an excellent tool to decrease the toxicity of venoms and isolated toxins. The mucus and venom samples of P. aiereba were irradiated using gamma rays from a {sup 60}Co source. Animals models were immunized with the native or irradiated mucus or venom. The assays were conducted to assess the production of antibodies by the immunized animals using enzyme immunoassay and western blotting. Preliminary results show the production of antibodies by the immunized animals. The resulting sera were also checked for antigenic cross- reactivity between venom and mucus, demonstrating the potential of mucus as an antigen for serum production for the specific treatment for accidents by stingrays. However, it is essential to carry out further tests in order to verify the neutralization of the toxin by antibodies formed by animals. (author)

  17. Hepatocyte growth factor protects endothelial cells against gamma ray irradiation-induced damage

    Institute of Scientific and Technical Information of China (English)

    Shun-ying HU; Hai-feng DUAN; Qing-fang LI; Yue-feng YANG; Jin-long CHEN; Li-sheng WANG; Hua WANG

    2009-01-01

    Aim:To investigate the effect of HGF on proliferation, apoptosis and migratory ability of human vascular endothelial cells against gamma ray irradiation.Methods: ECV304 cells derived from adult human umbilical vein endothelial cells (HUVEC) were irradiated with a single gamma ray dose of 20 Gy. Immunocytochemistry and Western blot analysis were used to detect c-Met protein expression and HGF/c-Met signal pathway. In the HGF-treated groups, ECV304 cells were incubated with HGF (20 or 40 ng/mL) 3 h prior to irradiation. At 48 h post-irradiation, the proliferation of ECV304 cells was measured by MTT assay, the apoptosis was assessed by flow cytometry, and the migratory ability of ECV304 cells was measured by transwell chamber assay.Results: c-Met protein is expressed in ECV304 cells and can be activated by HGF. Gamma ray irradiation inhibits proliferation and migration of ECV304 cells in a dose-dependent manner. HGF significantly promoted the proliferation of ECV304 cells, and flow cytom-etry revealed that HGF can inhibit apoptosis of ECV304 cells. Transwell chamber assay also showed that HGF increases migration activity of endothelial cells.Conclusion: HGF may afford protection to vascular endothelial cells against gamma ray irradiation-induced damage.

  18. Influence of irradiation upon few-layered graphene using electron-beams and gamma-rays

    Science.gov (United States)

    Wang, Yuqing; Feng, Yi; Mo, Fei; Qian, Gang; Chen, Yangming; Yu, Dongbo; Wang, Yang; Zhang, Xuebin

    2014-07-01

    Few-layered graphene (FLG) is irradiated by electron beams and gamma rays. After 100 keV electron irradiation, the edges of FLG start bending, shrinking, and finally generate gaps and carbon onions due to sputtering and knock-on damage mechanism. When the electron beam energy is increased further to 200 keV, FLG suffers rapid and catastrophic destruction. Unlike electron irradiation, Compton effect is the dominant damage mechanism in gamma irradiation. The irradiation results indicate the crystallinity of FLG decreases first, then restores as increasing irradiation doses, additionally, the ratio (O/C) of FLG surface and the relative content of oxygen groups increases after irradiation.

  19. Grafting study of polysulfone polymeric membranes by gamma ray irradiation; Estudo da grafitizacao de membranas polimericas a base de polissulfona por irradiacao gama

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    Radiation-induced grafting of styrene poli sulfone films were investigated by simultaneous method in solution using gamma-ray from a radio nuclide {sup 60}Co source. The gamma-ray energy of high intensity induced breaking of chemical bonds leading to free radical formation. The radical start a conventional polymerization sequence comparable with that obtained with a chemical catalyst acting as initiator. The effects of grafting conditions such as irradiation total dose, dose rate and addition of cross linking agent, were studied by means of morphology analysis, thermal degradation and crystallinity. After the grafting reaction, the membranes were submitted to an exhaustive extraction with solvent to remove the polystyrene homopolymer formed. The degree of grafting (DOG) was analyzed by percentage of weight increase. As a result, the reaction always follows the same pattern: DOG increases rapidly initially whilst propagation is the main reaction, then more slowly as termination becomes more frequent. (author)

  20. Preparation of poly (Vinyl Alcohol) nanofibers containing silver nanoparticles by gamma-ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yun Hye [AMOTECH Co., Ltd., Kimpo (Korea, Republic of); Shin, Jun Wha; An, Sung Jun; Youn, Min Ho; Lim, Youn Mook; Gwon, Hui Jeong; Nho, Young Chang [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2008-08-15

    PVA nanofibers containing silver nanoparticles were prepared by two methods. The first method was electrospinning of irradiated solution. The prepared PVA/AgNO{sub 3} solution was irradiated by gamma-rays. And then the irradiated solution was electrospun. The second method was irradiation of electrospun nanofibers. Nanofibers prepared by electrospinning of unirradiated PVA/AgNO{sub 3} solution. The morphology of the nanofibers was observed with a SEM, TEM. When the irradiated PVA/AgNO{sub 3} solution were electrospun, the average size of the Ag nanoparticles was increased, but their number was decreased.

  1. Dose-dependent and gender-related radiation-induced transcription alterations of Gadd45a and Ier5 inhuman lymphocytes exposed to gamma ray emitted by (60)Co.

    Science.gov (United States)

    Tavakoli, Hassan; Manoochehri, Mahdi; Modarres Mosalla, Sayed Mahdi; Ghafori, Mostafa; Karimi, Ali Akbar

    2013-04-01

    Growth arrest DNA damage-inducible 45a gene (Gadd45a) and immediate early response gene 5 (Ier5) have been emphasised as ideal radiation biomarkers in several reports. However, some aspects of radiation-induced transcriptional alterations of these genes are unknown. In this study, gender-dependency and dose-dependency as two factors that may affect radiation-induced transcription of Gadd45a and Ier5 genes were investigated. Human lymphocyte cells from six healthy voluntary blood donors (three women and three men) were irradiated in vitro with doses of 0.5-4.0 Gy from a (60)Co source and RNA isolated 4 h later using the High Pure RNA Isolation Kit. Dose and gender dependency of radiation-induced transcriptional alterations of Gadd45a and Ier5 genes were studied by quantitative real-time polymerase chain reaction. The results showed that as a whole, Gadd45a and Ier5 gave responses to gamma rays, while the responses were independent of radiation doses. Therefore, regardless of radiation dose, Gadd45a and Ier5 can be considered potential radiation biomarkers. Besides, although radiation-induced transcriptional alterations of Gadd45a in female and male lymphocyte samples were insignificant at 0.5 Gy, at other doses, their quantities in female samples were at a significantly higher level than in male samples. Radiation-induced transcription of Ier5 of females samples had a reduction in comparison with male samples at 1 and 2 Gy, but at doses of 0.5 and 4 Gy, females were significantly more susceptible to radiation-induced transcriptional alteration of Ier5.

  2. Modified the optical and electrical properties of CR-39 by gamma ray irradiation

    Directory of Open Access Journals (Sweden)

    A.M. Abdul-Kader

    2014-07-01

    Full Text Available The radiation technique is a useful technology technique to induce suitable modifications of the polymeric materials. In the present work, poly allyl diglycol carbonate (CR-39 solid state nuclear track detector samples were irradiated using different doses (150–950 kGy of gamma ray irradiations. The effect of gamma ray irradiations on the optical and electrical, properties of CR-39 was investigated. The obtained results showed a decrease in the optical energy gap with increasing the gamma dose. Increase in the numbers of carbon atoms (N in a formed cluster with increasing the irradiation dose was observed. Meanwhile, an increase in the Ac conductivity was obtained with increasing the gamma dose. Also, the variation in the dielectric constant and loss with irradiation dose was studied at the room temperature. The results indicate that the gamma ray irradiations in the dose range 150–950 kGy enhance the optical and electrical properties of the CR-39 polymer samples.

  3. Assessment of differences between X and gamma rays in order to validate a new generation of irradiators for insect sterilization

    Energy Technology Data Exchange (ETDEWEB)

    Mastrangelo, Thiago; Walder, Julio M.M., E-mail: piaui@cena.usp.b [Centro de Energia Nuclear na Agricultura (CENA), Piracicaba, SP (Brazil); Parker, Andrew G.; Jessup, Andrew; Orozco-Davila, Dina; Islam, Amirul; Dammalage, Thilakasiri, E-mail: A.Jessup@iaea.or [Joint FAO/IAEA-UN A-2444, Seibersdorf (Austria). Insect Pest Control Subprogramme; Pereira, Rui, E-mail: R.Cardoso-Pereira@iaea.or [Joint FAO/IAEA-UN, Vienna (Austria). Insect Pest Control Subprogramme

    2009-07-01

    Recent fears of terrorism provoked an increase in delays and denials of transboundary shipments of radioisotopes. This represents a serious constraint to sterile insect technique (SIT) programs around the world as they rely on the use of ionizing energy from radioisotopes for insect sterilization. In order to validate a novel Xray irradiator, a series of studies on Ceratitis capitata (Wiedemann) and Anastrepha fraterculus (Wiedemann) (Diptera: Tephritidae) were carried out, comparing the relative biological effectiveness (RBE) between X-rays and traditional gamma radiation from {sup 60}Co. Male C. capitata pupae and pupae of both sexes of A. fraterculus, both 24 to 48 h before adult emergence, were irradiated with doses ranging from 15 to 120 Gy and 10 to 70 Gy respectively. Estimated mean doses of 91.2 Gy of X and 124.9 Gy of gamma radiation induced 99% sterility in C. capitata males. Irradiated A. fraterculus were 99% sterile at about 40-60 Gy for both radiation treatments. Standard quality control parameters were not significantly affected by the two types of radiation. There were no significant differences between X and gamma radiation regarding mating indices. The RBE did not differ significantly between the tested X and gamma radiation, and X-rays are as biologically effective for SIT purposes as gamma rays are. This work confirms the suitability of this new generation of X-ray irradiators for pest control programs in UN Member States. (author)

  4. Effects of gamma-ray irradiation on leaching of simulated 133Cs+ radionuclides from geopolymer wasteforms

    Science.gov (United States)

    Deng, Ning; An, Hao; Cui, Hao; Pan, Yang; Wang, Bing; Mao, Linqiang; Zhai, Jianping

    2015-04-01

    Leaching of simulated 133Cs+ radionuclides from geopolymer wasteforms was examined with regard to effects from gamma-ray irradiation. Specifically, the compressive strengths, microstructures, pore structures, and leaching resistance of geopolymer wasteforms before and after irradiation were characterized. The leaching experiments were performed by immersion of wasteforms in deionized water, ground water, and seawater. It was found that gamma rays did not produce significant morphological changes, except for changes in the pore size distribution. The cumulative leaching fraction of all the leachants from the irradiated samples increased relative to the non-radiated samples, particularly during long leaching periods (11-42 days). These results, and those from a mercury intrusion porosimeter analysis, can be attributed to irradiation-induced changes in pore structure. All the leaching indexes were greater than the minimum acceptable value of 6.0 set by the American Nuclear Society Standards committee, which indicated that the fly-ash geopolymers are suitable for radionuclide immobilization. However, the effects of gamma-ray irradiation on the immobilization of radionuclides cannot be ignored.

  5. Gamma ray irradiation inhibits Plasmodium falciparum multiplication in in vitro culture supplemented with tritium labeled hypoxanthine

    Directory of Open Access Journals (Sweden)

    HARRY NUGROHO EKO SURNIYANTORO

    2016-04-01

    Full Text Available Abstract. Surniyantoro HNE, Darlina, Nurhayati S, Tetriana D, Syaifudin M. 2015. Gamma ray irradiation inhibits Plasmodium falciparum multiplication in in vitro culture supplemented with tritium labeled hypoxanthine. Nusantara Bioscience 8: 8-13. Malaria remains a major public health threat in the world. Therefore an attempt to create malaria vaccine for supporting the control of disease was taken by attenuating parasites with gamma rays and it was proven effective based on microscopic observation. Objective of this research was to assess the effectiveness of gamma rays to attenuate malaria parasites based on isotopic method. A laboratory strain of P. falciparum (3D7 was in vitro cultured with standard procedure and it was irradiated with gamma rays at doses of 150-250 Gy and unirradiated parasites served as control. Twenty four hours after 1-2 µCi of 3H-hypoxanthine was added into culture 100 µl of medium was taken and was repeated at various times, then hypoxanthine incorporation was measured with beta counter. Microscopic observation of parasitemia in culture was also done. The results showed that there was a fluctuation in multiplication of parasites post irradiation mainly in higher dose (more than150 Gy. Irradiated of parasites were more active in incorporate with purine precursor up to 48 hours. Parasites returned to their highest activity at 116 hours after hypoxanthine addition. No significant difference was found among doses of irradiation with p of 0.05. This was quite different with the finding from microscopic observation. It was known that dose of 150 Gy was the most effective dose for inhibiting of the parasite multiplication where some factors affecting these facts.

  6. Accumulation efficiency of cancer stem-like cells post {gamma}-ray and proton irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Quan Yi; WangWeikang; Fu Qibin; Mei Tao; Wu Jingwen; Li Jia [State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China); Yang, Gen, E-mail: gen.yang@pku.edu.cn [State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China); Wang Yugang [State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China)

    2012-09-01

    Ionizing radiation (IR) has been proven to be a powerful medical treatment in cancer therapy. Rational and effective use of its killing power depends on understanding IR-mediated responses at the molecular, cellular and tissue levels. Increasing evidence supports that cancer stem-like cells (CSCs) play an important role in tumor regrowth and spread post radiotherapy, for they are resistant to various therapy methods including radiation. Presently, SW620 colon carcinoma monolayer culture cells were irradiated with {gamma}-rays and protons of 2 Gy. Then apoptosis, clonogenic survival and the expression of CD133{sup +} protein were examined. The results showed that there was no significantly difference either on long-term clonogenic survival or on short-term apoptosis ratio. However, compared with {gamma}-rays, irradiation with protons was less efficient to accumulate CSCs at the same dose, although both protons and {gamma}-rays can significantly accumulate the CD133{sup +} CSCs subpopulation. In addition, the results of sphere formation assay also confirmed that proton irradiation is less efficient in CSCs accumulation, suggesting proton irradiation might have higher efficiency in CSCs elimination for cancer radiotherapy.

  7. Glasses, Coatings, Glues and Gamma-ray Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Barcala, J.M.; Fernandez, M. G.; Ferrando, A.; Fuentes, J.; Josa, M. I.; Molinero, A.; Oller, J. C. [Ciemat. Madrid (Spain); Arce, P.; Calvo, E.; Figueroa, C. F.; Rodrigo, T.; Vila, I.; Virto, A. L. [Universidad de Cantabria. Santander (Spain); Beigveder, J. M.; Genova, I.; Perez, G.; Ruiz, J. A. [CIDA. Madrid (Spain)

    2001-07-01

    Most of the alignment systems for LHC experiments use optomechanical elements confirming a network of points that are monitored by laser beams. LHC experiments, working at the expected nominal luminosity, will induce an extremely high irradiation. basic components such as glasses, coatings and glues may change and their performance may degrade significantly. We have tested various components and identified some of them that can stand 10 years of LHC operation. (Author) 11 refs.

  8. Effects of gamma-rays irradiation on OH/sup -/ doped KBr crystals

    Energy Technology Data Exchange (ETDEWEB)

    Scacco, A.; Somma, F. (Rome Univ. (Italy). Ist. di Fisica; Consiglio Nazionale delle Ricerche, Rome (Italy). Gruppo Nazionale di Struttura della Materia)

    1983-03-01

    Crystals of undoped and OH/sup -/ doped KBr have been ..gamma..-rays irradiated at room temperature. Colouring curves of doped samples show bleaching effects at high absorbed energy doses. This result is interpreted in terms of a reaction between the OH/sup -/ impurities and the formed F centres which predominates on the enhancement of the colouration due to the excess of anion vacancies induced by the OH/sup -/ defects.

  9. Study of uptake and endocytosis of gamma rays-irradiated crotoxin by mice peritoneal macrophages; Avaliacao do mecanismo de captacao e endocitose de crotoxina submetida a acao da radiacao, por macrofagos peritoneais de camundongos

    Energy Technology Data Exchange (ETDEWEB)

    Cardi, Bruno Andrade

    1999-07-01

    The purpose was to investigate the uptake and endocytosis of 2000 Gy {sup 60}Co irradiated crotoxin through mouse peritoneal macrophages, correlating with native one and another non related protein, the ovalbumin. Native (CTXN) or 2000 Gy {sup 60} Co {gamma}-rays (dose rate 540 Gy/hour) irradiated crotoxin (CTXI) or ovalbumin processed of same manner (OVAN - OVAI) were offered to mouse peritoneal macrophages and their uptake was evaluated by immunohistochemistry and quantitative in situ ELISA. The involvement of scavenger receptors (ScvR) was evaluated by using blockers drugs (Probuco-PBC or Dextran Sulfate - SD) or with nonspecific blocking using fetal calf serum (FBS). The morphology and viability of macrophages were preserved during the experiments. CTXI showed irradiation-induced aggregates and formation of oxidative changing were observed on this protein after gamma rays treatment. By immunohistochemistry we could observe heavy stained phagocytic vacuole on macrophages incubated with CTXI, as compared with CTXN. Quantitatively by in situ ELISA, the sema pattern was observed, displaying a 2-fold CTXI incorporation. In presence of PBC or SD we could find a significant decrease of CTXI uptake but not of CTXN. However the CTXN uptake was depressed by FBS, not observed with CTXI. OVA, after gamma rays treatment, underwent a high degradation suffering a potent incorporation and metabolism by macrophages, with a major uptake of OVAI in longer incubation (120 minutes). Gamma rays ({sup 60} Co) produced oxidative changes on CTX molecule, leading to a uptake by ScvR-mice peritoneal macrophages, suggesting that the relation antigen-presenting cells and gamma rays-modified proteins are responsible for the better immune response presented by irradiated antigens. (author)

  10. Effects of Gamma-Ray Irradiation on Dielectric Surface Breakdown of Polybutylene Naphthalate and Polybutylene Terephthalate Under Reduced Pressure

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    With the increasing application of electric and electronic devices in space and nuclear power stations, the polymeric insulation materials are inevitably exposed to various kinds of environments. Accordingly, it becomes necessary to investigate the effects of the radiation and air pressure on insulation materials. This paper describes the effects of gamma-ray irradiation and reduced pressure on dielectric breakdown of polybutylene naphthalate (PBN) and polybutylene terephthalate (PBT) by applying a DC pulse voltage. Both PBN and PBT were irradiated in air up to 100 kGy and then up to 1 000 kGy with a dose rate of 10 kGy/h by using a 60Co gamma-source. The effects of total dose and reduced pressure on the time to dielectric breakdown and discharge quantity were discussed. Obtained results show that, while increasing the total dose, the discharge quantity decreased with PBN, but increased with PBT. With decreasing the air pressure, the discharge quantity increased with PBN, but decreased with PBT. With increasing the total dose, the time to dielectric breakdown increased with PBN, but decreased with PBT. With decreasing the air pressure, the time to dielectric breakdown increased with both PBN and PBT. The experimental results suggest that the chemical structure of polybutylene polymers plays a main role in the result of radiation reaction,which is related to cross-linking and degradation reaction.

  11. Effect of irradiation (gamma rays) on the biology of Eimeria tenella oocysts

    Energy Technology Data Exchange (ETDEWEB)

    Bajwa, R.S.; Gill, B.S.

    1977-01-01

    Effect of gamma rays on the biology of the progeny of the irradiated Eimeria tenella oocysts was investigated. The parent inoculum of sporulated oocysts was exposed to 5 to 60 kR (gamma rays). These oocysts were fed to chicks. The oocysts voided by the chicks were collected and sporulated. The sporulation rate, pathogenicity, immunogenicity and reproduction potential of these oocysts--the progeny of the irradiated oocysts--were compared with those of the unirradiated oocysts. It was observed that increase of irradiation dose caused progressive decrease in the pathogenicity of the oocyst suspension. The oocysts exposed to 30 and 40 kR produced only mild infections whereas those exposed to 50 kR and above were noninfective. No difference in pathogenicity, immunogenicity and reproduction potential of unirradiated oocysts and the oocysts progeny of the irradiated oocysts was seen. It was concluded, therefore, that the effect of irradiation was limited to the inoculum exposed to it, and was not transmissible to the progeny of the irradiated oocysts.

  12. Avoidance behaviour and anxiety in rats irradiated with a sublethal dose of gamma-rays.

    Science.gov (United States)

    Tomášová, Lenka; Smajda, B; Bona, M

    2011-12-01

    The aim of this study was to assess, whether a sublethal dose of gamma-rays will influence the avoidance behaviour and anxiety in rats and whether the response to radiation depends on time of day of its application. Adult male Wistar rats were tested in elevated plus-maze, in hot plate test and in the light/dark box in 4 regular intervals during a day. After two weeks the animals were irradiated with a whole-body dose 6 Gy of gamma-rays. One day after irradiation the animals were repeatedly tested in the same way, as before irradiation. In the plus-maze test an increased level of anxiety was established. The irradiation significantly decreased the locomotor activity of rats, but the extent of exploratory and comfortable behaviour were not altered. After irradiation, an elevated aversion to the thermal stimulus was observed in the hot plate test. The effects of radiation were more pronounced in the light period of the day, than in the dark one. No significant differences in aversion to light were detected after irradiation. The obtained results indicate, that sublethal doses of ionizing radiation can markedly influence the reactivity of animals to adverse stimuli, their motoric activity and emotional status, as well.

  13. Immunohistochemical study on effects of [sup 60]Co [gamma] irradiation on salivary gland ducts of rat

    Energy Technology Data Exchange (ETDEWEB)

    Saitoh, Kazuhiko (Meikai Univ., Sakato, Saitama (Japan). School of Dentistry)

    1992-09-01

    Cytokeratin distribution in salivary glands was detected by use of polyclonal antikeratin antiserum (TK) and monoclonal antibodies (KL 1, RGE 53, and RPN 1164). The salivary glands of male rats received either 17.82 Gy or 27.97 Gy [sup 60]Co [gamma] irradiation in a single exposure and were then compared immunohistochemically with those of normal rats. Polyclonal anti-keratin antiserum (TK), which reacts with 41-65 KD keratins, stained almost all ducts in normal glands. RPN 1164 (no. 8 keratin) staining was negative in intercalated ducts of normal parotid and submandibular glands, but strongly positive in both striated and excretory ducts of these glands. Monoclonal antibody KL 1 (55-57 KD keratins) and RGE 53 (no. 18 keratin) did not bind to any ductal or acinar epithelia. Only in the sublingual gland were acini positive for TK staining, possibly indicating myoepithelial cells. No effects of [sup 60]Co [gamma] irradiation were apparent regarding keratin distribution in the intercalated in apical cytoplasm by [sup 60]Co [gamma] irradiation. Also, in the excretory duct, the basal side of the cells exhibited weakened staining following [sup 60]Co [gamma] irradiation were the most significant in the parotid and the least in the sublingual gland. Also this reaction depended upon the doses of [sup 60]Co used. The present findings suggested that negative or weakened staining at the basal and perinuclear portions of striated duct cells specifically reflects the primary or secondary cell damage produced by [sup 60]Co [gamma] irradiation. Since the distribution of cytoskeletal proteins in the cytoplasm reflects certain pathological conditions, immunohistochemical detection of these proteins seem to have a diagnostic value with respect to cellular injury. (J.P.N.) 77 refs.

  14. Effect of gamma ray irradiation on the structural and electrical transport properties of PrFe{sub 1−x}Mn{sub x}O{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Sultan, Khalid, E-mail: ksbhat.phy@gmail.com; Ikram, M., E-mail: ksbhat.phy@gmail.com [Department of Physics, National Institute of Technology Hazratbal, Srinagar-190006, Jammu and Kashmir (India); Asokan, K. [Material Science Division, Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi-110067 (India)

    2014-04-24

    The effect of gamma ray irradiation on the structural and transport properties of polycrystalline bulk samples of PrFe{sub 1−x}Mn{sub x}O{sub 3} (x = 0.0, 0.1, 0.5) were investigated. The samples were synthesized by solid state reaction method and exposed to {sup 60}Co gamma radiation to accumulated dose of 625 KGy. From the Raman study, the modes exhibit a blue shift with broadening of spectral features in the irradiated samples. The dielectric constant (ε′) was also studied as a function of frequency. The dielectric constant and ac conductivity increases with Mn doping but decrease on irradiation. Exposure to gamma radiation results in substantial modification in the physical properties of these compounds.

  15. 49. Biological dose assessment by the analyses of chromosomal aberrations and CB micronuclei in two victims accidentally exposed to 60Co gamma-rays

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@Biological doses were estimated by using the yields of dicentrics plus rings(dic+r) and cytokinesis-block micronuclei (CBMN) for two victims of the 60Co radiation source accident occurred on Mar 6,2001 in the City of Xuchang(victim A), and Jun 26,2001 in the City of Kaifeng(victim B), Henan Province, respectively. The whole blood of the victim A (male, 37 years old) and the victim B (female, 27 years old)

  16. Repair of skin damage during fractionated irradiation with gamma rays and low-LET carbon ions.

    Science.gov (United States)

    Ando, Koichi; Koike, Sachiko; Uzawa, Akiko; Takai, Nobuhiko; Fukawa, Takeshi; Furusawa, Yoshiya; Aoki, Mizuho; Hirayama, Ryoichi

    2006-06-01

    In clinical use of carbon-ion beams, a deep-seated tumor is irradiated with a Spread-Out Bragg peak (SOBP) with a high-LET feature, whereas surface skin is irradiated with an entrance plateau, the LET of which is lower than that of the peak. The repair kinetics of murine skin damage caused by an entrance plateau of carbon ions was compared with that caused by photons using a scheme of daily fractionated doses followed by a top-up dose. Right hind legs received local irradiations with either 20 keV/microm carbon ions or gamma rays. The skin reaction of the irradiated legs was scored every other day up to Day 35 using a scoring scale that consisted of 10 steps, ranging from 0.5 to 5.0. An isoeffect dose to produce a skin reaction score of 3.0 was used to obtain a total dose and a top-up dose for each fractionation. Dependence on a preceding dose and on the time interval of a top-up dose was examined using gamma rays. For fractionated gamma rays, the total dose linearly increased while the top-up dose linearly decreased with an increase in the number of fractions. The magnitude of damage repair depended on the size of dose per fraction, and was larger for 5.2 Gy than 12.5 Gy. The total dose of carbon ions with 5.2 Gy per fraction did not change till 2 fractions, but abruptly increased at the 3rd fraction. Factors such as rapid repopulation, induced repair and cell cycle synchronization are possible explanations for the abrupt increase. As an abrupt increase/decrease of normal tissue damage could be caused by changing the number of fractions in carbon-ion radiotherapy, we conclude that, unlike photon therapy, skin damage should be carefully studied when the number of fractions is changed in new clinical trials.

  17. Effect of N-acetyl-l-cysteine on Saccharomyces cerevisiae irradiated with gamma-rays.

    Science.gov (United States)

    Kim, Jin Kyu; Park, Jiyoung; Ryu, Tae Ho; Nili, Mohammad

    2013-07-01

    Ionizing radiation (IR) induces DNA strand breaks (DSBs), base damage, inhibition of protein activity, apoptosis by reactive oxygen species (ROS). Detoxification or removal of generated ROS can reduce oxidative damage. Antioxidant enzymes such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase are immediately triggered for ROS scavenging. N-acetyl-l-cysteine (NAC) having a thiol, a precursor for reduced glutathione (GSH), is known as one of the antioxidants. In this study, the effect of NAC as an antioxidant and a radioprotector was investigated on survival rate, transcriptional level of antioxidant enzymes gene, and protein level including SOD activity and intracellular GSH in yeast Saccharomyces cerevisiae W303-1A strain mutated YBP1 gene irradiated with gamma-rays. NAC did not protect the gamma-ray-induced cell death. The gene expression of antioxidant enzymes including SOD1, SOD2, GPX1, and GPX2 was induced by gamma-rays. In contrast, the pretreatment of NAC reduced the expression of these genes. NAC reduced SOD activity and intracellular GSH level in yeast. These data suggest that NAC is able to reduce radiation-induced ROS levels in vivo but does not protect yeast cells against radiation-induced death.

  18. Bremsstrahlung {gamma}-ray generation by electrons from gas jets irradiated by laser pulses for radiographic testing

    Energy Technology Data Exchange (ETDEWEB)

    Oishi, Yuji; Nayuki, Takuya; Zhidkov, Alexei; Fujii, Takashi; Nemoto, Koshichi [Central Research Institute of Electric Power Industry, Yokosuka, Kanagawa 240-0196 (Japan); Central Research Institute of Electric Power Industry, Yokosuka, Kanagawa 240-0196, Japan and Photon Pioneers Center in Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871 (Japan); Central Research Institute of Electric Power Industry, Yokosuka, Kanagawa 240-0196 (Japan)

    2012-07-11

    Electron generation from a gas jet irradiated by low energy femtosecond laser pulses is studied experimentally as a promising source of radiation for radioisotope-free {gamma}-ray imaging systems. The calculated yield of {gamma}-rays in the 0.5-2 MeV range, produced by low-average-power lasers and gas targets, exceeds the yields from solid tape targets up to 60 times. In addition, an effect of quasi-mono energetic electrons on {gamma}-ray imaging is also discussed.

  19. Effect of gamma-ray irradiation on the dewaterability of waste activated sludge

    Science.gov (United States)

    Wu, Yuqi; Jiang, Yinghe; Ke, Guojun; Liu, Yingjiu

    2017-01-01

    The effect of gamma-ray irradiation on waste activated sludge (WAS) dewaterability was investigated with irradiation doses of 0-15 kGy. Time to filter (TTF50), specific resistance of filtration (SRF) and water content of sludge cake were measured to evaluate sludge dewaterability. Soluble chemical oxygen demand (SCOD), soluble extracellular polymeric substances (EPS) concentration and sludge particle size were determined to explain changes in sludge dewaterability. The optimal irradiation dose to obtain the maximum dewaterability characteristics was 1-4 kGy, which generated sludge with optimal disintegration (1.5-4.0%), soluble EPS concentration (590-750 mg/L) and particle size distribution (100-115 μm diameter). The combination of irradiation and cationic polyacrylamide (CPAM) addition exhibited minimal synergistic effect on increasing sludge dewatering rate compared with CPAM conditioning alone.

  20. Influence of gamma-ray irradiation on Faraday effect of Cu-doped germano-silicate optical fiber

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Youngwoong; Ju, Seongmin; Jeong, Seongmook; Jang, Myoung-Jin [Department of Physics and Photon Science, School of Information and Communications, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-Gu, Gwangju 500-712 (Korea, Republic of); Kim, Jong-Yeol; Lee, Nam-Ho; Jung, Hyun-Kyu [Nuclear Convergence Technology Development Department, Korea Atomic Energy Research Institute, 989-111 Daedeok-daero, Yuseong-gu, Daejeon (Korea, Republic of); Han, Won-Taek, E-mail: wthan@gist.ac.kr [Department of Physics and Photon Science, School of Information and Communications, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-Gu, Gwangju 500-712 (Korea, Republic of)

    2015-02-01

    Influence of gamma-ray irradiation on the Faraday effect of the Cu-doped germano-silicate optical fiber was investigated. The Verdet constant of the gamma-ray irradiated optical fiber at 660 nm was measured to be 3.07 rad T{sup −1} m{sup −1}, 1.46 times larger than that of before the irradiation at total dose of 1200 Gy. Cu-related radiation-induced defect centers and Cu metal particles which were reduced from Cu{sup 2+} ions by the irradiation are thought to be responsible for the increase in the Verdet constant of the optical fiber.

  1. Electron beam and gamma ray irradiated polymer electrolyte films: Dielectric properties

    Directory of Open Access Journals (Sweden)

    S. Raghu

    2016-04-01

    Full Text Available In this study, polymer electrolyte films were irradiated with electron beam (EB and Gamma ray (GR at 50 and 150 kGy. The induced chemical changes in films due to irradiations have been confirmed from the Fourier Transform Infra red (FT-IR spectra. The X-ray Diffractometry (XRD results show that crystallinity decreases by ∼20% in EB and ∼10% in GR irradiated films respectively compared to non-irradiated film. The micro structural arrangement was investigated by Scanning Electronic Microscopy (SEM and the images reveal that there is a substantial improvement in the surface morphology in irradiated films. The real (ε′ and imaginary (ε″ dielectric constant and AC conductivity are found to increase with increase in irradiation dose. Improved dielectric properties and conductivity (1.74 x 10−4 & 1.15 x 10−4 S/cm, respectively, for EB and GR irradiated films at room temperature after irradiation and it confirm that EB and GR irradiation can be simple and effective route to obtaining highly conductive polymer electrolytes. From this study it is confirm that EB is more effectiveness than GR irradiation.

  2. Behavior of Random Hole Optical Fibers under Gamma Ray Irradiation and Its Potential Use in Radiation Sensing Applications

    Directory of Open Access Journals (Sweden)

    Anbo Wang

    2007-05-01

    Full Text Available Effects of radiation on sensing and data transmission components are of greatinterest in many applications including homeland security, nuclear power generation, andmilitary. A new type of microstructured optical fiber (MOF called the random hole opticalfiber (RHOF has been recently developed. The RHOFs can be made in many differentforms by varying the core size and the size and extent of porosity in the cladding region.The fibers used in this study possessed an outer diameter of 110 μm and a core ofapproximately 20 μm. The fiber structure contains thousands of air holes surrounding thecore with sizes ranging from less than 100 nm to a few μm. We present the first study ofthe behavior of RHOF under gamma irradiation. We also propose, for the first time to ourknowledge, an ionizing radiation sensor system based on scintillation light from ascintillator phosphor embedded within a holey optical fiber structure. The RHOF radiationresponse was compared to normal single mode and multimode commercial fibers(germanium doped core, pure silica cladding and to those of radiation resistant fibers (puresilica core with fluorine doped cladding fibers. The comparison was done by measuringradiation-induced absorption (RIA in all fiber samples at the 1550 nm wavelength window(1545 ± 25 nm. The study was carried out under a high-intensity gamma ray field from a 60Co source (with an exposure rate of 4x104 rad/hr at an Oak Ridge National Laboratory gamma ray irradiation facility. Linear behavior, at dose values less than 106 rad, was observed in all fiber samples except in the pure silica core fluorine doped cladding fiber which showed RIA saturation at 0.01 dB. RHOF samples demonstrated low RIA (0.02 and 0.005 dB compared to standard germanium doped core pure silica cladding (SMF and MMF fibers. Results also showed the possibility of post-fabrication treatment to improve the radiation resistance of the RHOF fibers.

  3. Digested livestock wastewater treatment using gamma-ray irradiation and struvite crystallization

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tak Hyun; Lee, Sang Ryul; Nam, Youn Ku; Lee, Myun Joo [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2009-06-15

    Livestock wastewater generally contains high strength of organics (COD), ammonia nitrogen (NH{sub 4}{sup +} -N), phosphate phosphorus (PO{sub 4}{sup 3-} -P) and suspended solids. It is very difficult to treat by conventional wastewater treatment techniques. In this study, struvite crystallization was carried out to treat the digested livestock wastewater. 1.0 :1.2 :1.2 was determined as an optimal NH{sub 4}+ :Mg{sup 2+} : PO{sub 4}{sup 3-} mol ratio of struvite crystallization. For the digested livestock wastewater, COD, NH{sub 4}{sup +} -N and PO{sub 4}{sup 3-} -P removal efficiencies by struvite crystallization were 72.4%, 98.9%, and 74.8%, respectively. Gamma-ray irradiation was carried out prior to struvite crystallization of livestock wastewater. The enhancement of struvite crystallization efficiency could be obtained by the pretreatment of gamma-ray irradiation due to the decrease of COD, NH{sub 4}{sup +} -N and PO{sub 4}{sup 3-} -P concentration.

  4. Mortality and growth of cobalt-60 gamma-irradiated adult Pacific oyster, Crassotrea gigas%60Co-γ射线对成体长牡蛎生长的影响及致死效应

    Institute of Scientific and Technical Information of China (English)

    刘晓; 彭小明; 张国范; 赵敏; 郭希明

    2005-01-01

    Effects of ionizing irradiation of 60Co-γ ray on mortality and growth of one year-old Pacific oysters ( Crassotrea gigas ) were studied. Irradiation was conducted at 4℃ and without sea water, and the survival, shell length, shell width, whole wet weight and condition index of irradiated oysters were measured. A biphasic dose response effect of 660Co-γ irradiation on Pacific oyster with high stimulatory response dose range to 100 Gy, and strong hormesis effects had been observed. Gamma ray induced mortality happened within 90 days after irradiation, and the relation between dosage ( D ) and mortality at 90 days could be described by the equation of M90 = 0.0041D2- 0. 1816D (R2= 0. 9958) with an LD50/90 of 135 Gy, indicating that the Pacific oyster has strong resistance to 60Coirradiation. Growth in shell length, shell width and whole wet weight of Pacific oyster were also enhanced by 60 Gy of 60Co-γ ray. The condition index was also enhanced by 60Coirradiation in the dosage range from 40 to 100 Gy, with the maximum stimulatory response of 2.5 fold of control value at the 40 Gy dosage, suggesting that the accelerating effects of γ ray on growth of the Pacific oyster led to increase in dry meat. Results of this study showed that ionizing irradiation might be useful in the improvement of production traits in shellfish.

  5. Inactivation effect of 60Co gamma ray on cysticerci of Taenia solium in pork%60Coγ射线对猪肉中囊尾蚴的辐照杀灭效应

    Institute of Scientific and Technical Information of China (English)

    钟凯; 高翔; 计融

    2011-01-01

    Objective revealing the relationship between irradiation dose and inactivation ratio for eysticerei of Taenia solium in pork, determining the minimal dose for totally killing cysticerci and providing scientific evidence for setting up relevant hygienic standards of radiation. Methods After Taenia solium infected pork being treated with different irradiation doses; cysticerci were separated and incubated in fresh swine bile. The adjusted inactivation ratio was calculated according to the survival rate. Results There was a linear correlation between irradiation dose and adjusted inactivation ratio, the D10 value was about 3.8 kGy, and a totally killing could be achieved by 4.5 kGy irradiation. Conclusion Irradiation at a dose of 4.5 kGy could be applied as the maximum dose to inactivate cysticerci of Taenia solium in pork processing.%目的 揭示猪肉中囊尾蚴灭活率与辐照剂量的相关关系及最小杀灭剂量,为制定相应辐照卫生规范提供科学依据.方法 以不同剂量Co γ射线处理感染囊尾蚴的猪肉,并用新鲜猪胆汁孵化剥离出的囊尾蚴,根据成活率计算校正灭活率.结果 辐照剂量与校正灭活率具有线性相关,D值约为3.8 kGy,4.5 kGy可完全杀灭囊尾蚴.结论 4.5 kGy γ射线对猪肉中囊尾蚴有很好的杀灭效果.

  6. Effects of neonatal. gamma. -ray irradiation on rat hippocampus: Pt. 1; Postnatal maturation of hippocampal cells

    Energy Technology Data Exchange (ETDEWEB)

    Represa, A.; Dessi, F.; Beaudoin, M.; Ben-Ari, Y. (Institut National de la Sante et de la Recherche Medicale (INSERM), 75 - Paris (France))

    1991-01-01

    The axons of dentate granule cells, the mossy fibres, establish synaptic contacts with the thorny excrescences of the apical dendrite of CA3 pyramidal neurons. Dentate granule cells develop postnatally in rats, whereas the CA3 pyramidal cells are generated before birth. In the present studies, using unilateral neonatal {gamma}-ray irradiation to destroy the granule cells in one hemisphere, we have studied the effect of mossy fibre deprivation on the development of their targets. We show that such ''degranulation'' prevents the normal development of giant thorny excrescences, suggesting that the development of thorny excrescences in CA3 pyramidal neurons is under the control of mossy fibres. In contrast, irradiation of the hippocampus of the neonatal rat does not affect the development of the dendritic arborization of CA3 pyramidal cells and their non-mossy dendritic spines. (author).

  7. Degradation and annealing studies on gamma rays irradiated COTS PPD CISs at different dose rates

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zujun, E-mail: wangzujun@nint.ac.cn [State Key Laboratory of Intense Pulsed Irradiation Simulation and Effect, Northwest Institute of Nuclear Technology, P.O.Box 69-10, Xi’an (China); Ma, Yingwu [State Key Laboratory of Intense Pulsed Irradiation Simulation and Effect, Northwest Institute of Nuclear Technology, P.O.Box 69-10, Xi’an (China); Liu, Jing [School of Materials Science and Engineering, Xiangtan University, Xiangtan, 411105 Hunan (China); Xue, Yuan; He, Baoping; Yao, Zhibin; Huang, Shaoyan; Liu, Minbo; Sheng, Jiangkun [State Key Laboratory of Intense Pulsed Irradiation Simulation and Effect, Northwest Institute of Nuclear Technology, P.O.Box 69-10, Xi’an (China)

    2016-06-01

    The degradation and annealing studies on Colbalt-60 gamma-rays irradiated commercial-off-the-shelf (COTS) pinned photodiode (PPD) CMOS image sensors (CISs) at the various dose rates are presented. The irradiation experiments of COTS PPD CISs are carried out at 0.3, 3.0 and 30.0 rad(Si)/s. The COTS PPD CISs are manufactured using a standard 0.18-μm CMOS technology with four-transistor pixel PPD architecture. The behavior of the tested CISs shows a remarkable degradation after irradiation and differs in the dose rates. The dark current, dark signal non-uniformity (DSNU), random noise, saturation output, signal to noise ratio (SNR), and dynamic range (DR) versus the total ionizing dose (TID) at the various dose rates are investigated. The tendency of dark current, DSNU, and random noise increase and saturation output, SNR, and DR to decrease at 3.0 rad(Si)/s are far greater than those at 0.3 and 30.0 rad(Si)/s. The damage mechanisms caused by TID irradiation at the various dose rates are also analyzed. The annealing tests are carried out at room temperature with unbiased conditions after irradiation.

  8. Evaluation of some selected vaccines and other biological products irradiated by gamma rays, electron beams and X-rays

    Science.gov (United States)

    May, J. C.; Rey, L.; Lee, Chi-Jen

    2002-03-01

    Molecular sizing potency results are presented for irradiated samples of one lot of Haemophilus b conjugate vaccine, pneumococcal polysaccharide type 6B and typhoid vi polysaccharide vaccine. The samples were irradiated (25 kGy) by gamma rays, electron beams and X-rays. IgG and IgM antibody response in mice test results (ELISA) are given for the Hib conjugate vaccine irradiated at 0°C or frozen in liquid nitrogen.

  9. Evaluation of some selected vaccines and other biological products irradiated by gamma rays, electron beams and X-rays

    Energy Technology Data Exchange (ETDEWEB)

    May, J.C. E-mail: may@cber.fda.gov; Rey, L.; Lee, C.-J

    2002-03-01

    Molecular sizing potency results are presented for irradiated samples of one lot of Haemophilus b conjugate vaccine, pneumococcal polysaccharide type 6B and typhoid vi polysaccharide vaccine. The samples were irradiated (25 kGy) by gamma rays, electron beams and X-rays. IgG and IgM antibody response in mice test results (ELISA) are given for the Hib conjugate vaccine irradiated at 0 deg. C or frozen in liquid nitrogen.

  10. Tenth value layers for 60Co gamma rays and for 4, 6, 10, 15, and 18 MV x rays in concrete for beams of cone angles between 0 degrees and 14 degrees calculated by Monte Carlo simulation.

    Science.gov (United States)

    Jaradat, Adnan K; Biggs, Peter J

    2007-05-01

    The calculation of shielding barrier thicknesses for radiation therapy facilities according to the NCRP formalism is based on the use of broad beams (that is, the maximum possible field sizes). However, in practice, treatment fields used in radiation therapy are, on average, less than half the maximum size. Indeed, many contemporary treatment techniques call for reduced field sizes to reduce co-morbidity and the risk of second cancers. Therefore, published tenth value layers (TVLs) for shielding materials do not apply to these very small fields. There is, hence, a need to determine the TVLs for various beam modalities as a function of field size. The attenuation of (60)Co gamma rays and photons of 4, 6, 10, 15, and 18 MV bremsstrahlung x ray beams by concrete has been studied using the Monte Carlo technique (MCNP version 4C2) for beams of half-opening angles of 0 degrees , 3 degrees , 6 degrees , 9 degrees , 12 degrees , and 14 degrees . The distance between the x-ray source and the distal surface of the shielding wall was fixed at 600 cm, a distance that is typical for modern radiation therapy rooms. The maximum concrete thickness varied between 76.5 cm and 151.5 cm for (60)Co and 18 MV x rays, respectively. Detectors were placed at 630 cm, 700 cm, and 800 cm from the source. TVLs have been determined down to the third TVL. Energy spectra for 4, 6, 10, 15, and 18 MV x rays for 10 x 10 cm(2) and 40 x 40 cm(2) field sizes were used to generate depth dose curves in water that were compared with experimentally measured values.

  11. Diversity analysis of mangosteen (Garcinia mangostana irradiated by gamma-ray based on morphological and anatomical characteristics

    Directory of Open Access Journals (Sweden)

    MUH RAHMAD SUHARTANTO

    2010-01-01

    Full Text Available Widiastuti A, Sobir, Suhartanto MR. 2010. Diversity analysis of mangosteen (Garcinia mangostana L. irradiated by gamma-ray based on morphological and anatomical characteristics. Nusantara Bioscience 2: 23-33. The aim of this research was to increase genetic variability of mangosteen (Garcinia mangostana L. irradiated by gamma rays dosage of 0 Gy, 20 Gy, 25 Gy, 30 Gy,35 Gy and 40 Gy. Plant materials used were seeds collected from Cegal Sub-village, Karacak Village, Leuwiliang Sub-district, Bogor District, West Java. Data was generated from morphological and anatomical characteristics. The result indicated that increasing of gamma ray dosage had inhibited ability of seed to growth, which needed longer time and decreased seed viability. Morphologically, it also decreased plant heigh, stem diameter, leaf seizure, and amount of leaf. Anatomically, stomatal density had positive correlation with plant height by correlation was 90% and 74%. Gamma rays irradiation successfully increase morphological variability until 30%. Seed creavage after irradiation increased variability and survival rate of mangosteen.

  12. Biochemical and hematological study of goats envenomed with natural and 60Co-irradiated bothropic venom

    Energy Technology Data Exchange (ETDEWEB)

    Lucas de Oliveira, P.C.; Madruga, R.A.; Barbosa, N.P.U. [Uberaba School of Veterinary Medicine (UNIUBE), MG (Brazil)]. E-mail: pedrolucaso@uol.com.br; Sakate, M. [UNESP, Botucatu, SP (Brazil). School of Veterinary Medicine and Animal Husbandry

    2007-07-01

    Venoms from snakes of the Bothrops genus are proteolytic, coagulant, hemorrhagic and nephrotoxic, causing edema, necrosis, hemorrhage and intense pain at the bite site, besides systemic alterations. Many adjuvants have been added to the venom used in the sensitization of antiserum-producer animals to increase antigenic induction and reduce the envenomation pathological effects. Gamma radiation from {sup 60}Co has been used as an attenuating agent of the venoms toxic properties. The main objective was to study, comparatively, clinical and laboratory aspects of goats inoculated with bothropic (Bothrops jararaca) venom, natural and irradiated from a {sup 60}Co source. Twelve goats were divided into two groups of six animals: GINV, inoculated with 0.5 mg/kg of natural venom; and GIIV, inoculated with 0.5 mg/kg of irradiated venom. Blood samples were collected immediately before and one, two, seven, and thirty days after venom injection. Local lesions were daily evaluated. The following exams were carried out: blood tests; biochemical tests of urea, creatinine, creatine kinase, aspartate amino-transferase and alanine amino-transferase; clotting time; platelets count; and total serum immunoglobulin measurement. In the conditions of the present experiment, irradiated venom was less aggressive and more immunogenic than natural venom. (author)

  13. Biochemical and hematological study of goats envenomed with natural and 60Co-irradiated bothropic venom

    Directory of Open Access Journals (Sweden)

    P. C. Lucas de Oliveira

    2007-01-01

    Full Text Available Venoms from snakes of the Bothrops genus are proteolytic, coagulant, hemorrhagic and nephrotoxic, causing edema, necrosis, hemorrhage and intense pain at the bite site, besides systemic alterations. Many adjuvants have been added to the venom used in the sensitization of antiserum-producer animals to increase antigenic induction and reduce the envenomation pathological effects. Gamma radiation from 60Co has been used as an attenuating agent of the venoms toxic properties. The main objective was to study, comparatively, clinical and laboratory aspects of goats inoculated with bothropic (Bothrops jararaca venom, natural and irradiated from a 60Co source. Twelve goats were divided into two groups of six animals: GINV, inoculated with 0.5mg/kg of natural venom; and GIIV, inoculated with 0.5mg/kg of irradiated venom. Blood samples were collected immediately before and one, two, seven, and thirty days after venom injection. Local lesions were daily evaluated. The following exams were carried out: blood tests; biochemical tests of urea, creatinine, creatine kinase (CK, aspartate amino-transferase (AST and alanine amino-transferase (ALT; clotting time; platelets count; and total serum immunoglobulin measurement. In the conditions of the present experiment, irradiated venom was less aggressive and more immunogenic than natural venom.

  14. Microdosimetry of DNA conformations: relation between direct effect of (60)Co gamma rays and topology of DNA geometrical models in the calculation of A-, B- and Z-DNA radiation-induced damage yields.

    Science.gov (United States)

    Semsarha, Farid; Raisali, Gholamreza; Goliaei, Bahram; Khalafi, Hossein

    2016-05-01

    In order to obtain the energy deposition pattern of ionizing radiation in the nanometric scale of genetic material and to investigate the different sensitivities of the DNA conformations, direct effects of (60)Co gamma rays on the three A, B and Z conformations of DNA have been studied. For this purpose, single-strand breaks (SSB), double-strand breaks (DSB), base damage (BD), hit probabilities and three microdosimetry quantities (imparted energy, mean chord length and lineal energy) in the mentioned DNA conformations have been calculated and compared by using GEometry ANd Tracking 4 (Geant4) toolkit. The results show that A-, B- and Z-DNA conformations have the highest yields of DSB (1.2 Gy(-1) Gbp(-1)), SSB (25.2 Gy(-1) Gbp(-1)) and BD (4.81 Gy(-1) Gbp(-1)), respectively. Based on the investigation of direct effects of radiation, it can be concluded that the DSB yield is largely correlated to the topological characteristics of DNA models, although the SSB yield is not. Moreover, according to the comparative results of the present study, a reliable candidate parameter for describing the relationship between DNA damage yields and geometry of DNA models in the theoretical radiation biology research studies would be the mean chord length (4 V/S) of the models.

  15. Study on Several Characteristics of Agaricus blazei Murril Strain J3 Irradiated by 60Co

    Institute of Scientific and Technical Information of China (English)

    WENG Bo-qi; JIANG Zhi-he; HUANG Ting-jun; CHEN Jian; ZHENG Wei-wen

    2003-01-01

    A new mutant strain J3 from Agaricus blazei Murril was obtained by 60Co irradiation. The yields of successive generations were increased more than 70% to compare with their original strain. The component analysis on amino acids and fatty acid illuminated that the nutrient value of strain J3 fruiting body was better than the original strain. The apparent nodule structure was found in the hyphea of J3 strain through the observation by scanning electron microscope. RAPD analysis showed the great difference of PCR fingerprints between J3 and its original strain. It is a promising mutant strain for further commercial development in the future.

  16. Optical characteristic variations in gamma ray irradiated polarization-maintaining optical fibers

    Science.gov (United States)

    Yokota, Hirohisa; Kameda, Yosuke; Imai, Yoh

    2017-02-01

    Polarization-maintaining (PM) optical fibers are introduced in fiber optic communication systems and optical fiber sensors to improve their performances. It is known that characteristics of optical fibers vary for radiation exposures, e.g., a transmission loss increment. It is important to clarify the characteristic variations of PM fibers by radiations in their applications. The radiation induced optical characteristic variation is also useful for an application of optical fibers including PM fibers as radiation sensors. In this paper, optical characteristic variations in gamma ray irradiated PM optical fibers with low modal birefringence were experimentally clarified indenting to apply a polarization optical time domain reflectometry to a distributed radiation sensor. It was confirmed that the transmission losses for both polarization modes in elliptical jacket fibers increased similar to ordinary silica based single-mode fibers, where the difference of transmission losses of two polarization modes was enhanced by the irradiation. We also clarified that the modal birefringence of the elliptical jacket fibers increased for the irradiation for the first time by the beat length measurement using the wavelength sweeping technique.

  17. Mutation Breeding of various spray chrysanthemum cultivars by gamma-ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang Hoon; Chung, Sung Jin; Kim, Dong Sub; Kim, Jin Baek; Kang, Si Yong [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Lee, Geung Joo [Mokpo National University, Muan (Korea, Republic of)

    2009-09-15

    This study was carried out to analyze mutation rate and spectrum of chrysanthemum by gamma-ray irradiation. Five flower types, 16 cultivars including 'Geumsu', 'Hwiparam', 'Ilwol', 'Magic', 'Moonlight', 'Noblewine', 'Pinky', 'Progy', 'Sangtte', 'Waterfog', 'Whitneypangpang', 'Yelloweye', 'Yellowpangpang', 'Yesmiso', 'Yesmorning', and 'Yestogether' were irradiated as 30, 50, and 70 Gy dose during 24 hours. As a result, mutation rate was identified as the highest in single type among five flower types, but there was a little difference according to cultivars. Mutation rate was increased in proportion to irradiation dose in anemone, pompon, and spider type cultivars, but there wasn't clear in single and semi-double type cultivars. Mutation spectrum was identified as the highest in the cultivar 'Noblewine'. The most sensitive cultivars to radiation were revealed as 'Noblewine' and 'Yesmorning' and the least were Moonlight', 'Waterfog', and 'Yellowpangpang'. Consequently, there was much difference in radio-sensitivity according to cultivars of chrysanthemum and flower type was correlated a little with mutation rate.

  18. Erythropoiesis in mice exposed to continuous whole body irradiation of gamma-rays

    Energy Technology Data Exchange (ETDEWEB)

    Joshima, Hisamasa; Fukutsu, Kumiko; Matsushita, Satoru; Kashima, Masatoshi

    1988-09-01

    The erythropoietic effects of continuous ..gamma..-irradiation with a daily regime of 0.029, 0.083 and 0.374 Gy were studied in mice. Irradiation was performed with /sup 137/Cs ..gamma..-rays for 22 hr/day. The length of irradiation time varied from 3 to 112 days. Erythropoiesis was investigated on the basis of clearance of /sup 59/Fe from the circulation and of incorporation of /sup 59/Fe into circulating erythrocytes and erythropoietic tissue. A chemical method for the separation of heme and nonheme iron-containing fractions was employed to examine the uptake of /sup 59/Fe into both the heme and nonheme iron fractions. Daily exposure to 0.029 and 0.083 Gy caused no significant changes in erythropoiesis. Daily exposure to 0.374 Gy caused some significant changes in erythropoiesis. On day 7 of continuous irradiation, the amount of /sup 59/Fe incorporated into erythrocytes decreased, but the values returned to normal on day 14 and 28 of continuous irradiation, indicating recovery within erythropoietic tissues at earlier time. On day 56, depressed incorporation of /sup 59/Fe into erythrocytes with normal rate of disappearance of /sup 59/Fe from the circulation and increased heme level of /sup 59/Fe in the femoral marrow were observed. Results observed on day 56 may suggest the possibility of ineffective erythropoiesis during the continuous irradiation. On day 112, some mice showed almost the same changes in erythropoiesis as those mice exposed to acute X-rays radiation.

  19. Seed germination of peanuts irradiated with cobalt ({sup 60}CO); Germinacao de sementes de amendoim irradiadas com cobalto ({sup 60}Co)

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Niedja Marrize C.; Almeida, Francisco de Assis C.; Gomes, Josivanda P.; Pessoa, Elvira B., E-mail: niedjamarizze@yahoo.com.b, E-mail: josivanda@deag.ufcg.edu.b, E-mail: elvirabe@gmail.co [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Dept. de Engenharia Agricola; Leal, Artur S. Cavalcanti, E-mail: arturcleal@yahoo.com.b [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Dept. de Engenharia de Materiais

    2010-07-01

    This work was realized to evaluate the effect of gamma irradiation ({sup 60}Co) at doses 0, 0.50, 1.00, 1.50, 2.00, 2.50, 3.00 and 4.00 kGy, on germination of seeds of peanut, cultivar BR1. Irradiation Department of Nuclear, UFPE, where he received after the irradiation, they were stored in packing of PET and polyethylene braided with a time of 90 days. Through the results, obtained monthly, concluded that the dose of 0.5 kGy was effective in the germination of seeds of peanut, not affecting its power of germination and overcoming the witness within 30 to 60 days. (author)

  20. A Performance Evaluation of a Notebook PC under a High Dose-Rate Gamma Ray Irradiation Test

    Directory of Open Access Journals (Sweden)

    Jai Wan Cho

    2014-01-01

    Full Text Available We describe the performance of a notebook PC under a high dose-rate gamma ray irradiation test. A notebook PC, which is small and light weight, is generally used as the control unit of a robot system and loaded onto the robot body. Using TEPCO’s CAMS (containment atmospheric monitoring system data, the gamma ray dose rate before and after a hydrogen explosion in reactor units 1–3 of the Fukushima nuclear power plant was more than 150 Gy/h. To use a notebook PC as the control unit of a robot system entering a reactor building to mitigate the severe accident situation of a nuclear power plant, the performance of the notebook PC under such intense gamma-irradiation fields should be evaluated. Under a similar dose-rate (150 Gy/h gamma ray environment, the performances of different notebook PCs were evaluated. In addition, a simple method for a performance evaluation of a notebook PC under a high dose-rate gamma ray irradiation test is proposed. Three notebook PCs were tested to verify the method proposed in this paper.

  1. Effects of gamma-ray irradiation on leaching of simulated {sup 133}Cs{sup +} radionuclides from geopolymer wasteforms

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Ning; An, Hao; Cui, Hao, E-mail: cuihao@nju.edu.cn; Pan, Yang; Wang, Bing; Mao, Linqiang; Zhai, Jianping

    2015-04-15

    Highlights: • γ-ray irradiation caused more Cs{sup +} leaching out from geopolymer wasteform. • Pore structure change induced by irradiation caused the increase of leachability. • Fly-ash-based geopolymer is a potential material for radionuclide immobilization. - Abstract: Leaching of simulated {sup 133}Cs{sup +} radionuclides from geopolymer wasteforms was examined with regard to effects from gamma-ray irradiation. Specifically, the compressive strengths, microstructures, pore structures, and leaching resistance of geopolymer wasteforms before and after irradiation were characterized. The leaching experiments were performed by immersion of wasteforms in deionized water, ground water, and seawater. It was found that gamma rays did not produce significant morphological changes, except for changes in the pore size distribution. The cumulative leaching fraction of all the leachants from the irradiated samples increased relative to the non-radiated samples, particularly during long leaching periods (11–42 days). These results, and those from a mercury intrusion porosimeter analysis, can be attributed to irradiation-induced changes in pore structure. All the leaching indexes were greater than the minimum acceptable value of 6.0 set by the American Nuclear Society Standards committee, which indicated that the fly-ash geopolymers are suitable for radionuclide immobilization. However, the effects of gamma-ray irradiation on the immobilization of radionuclides cannot be ignored.

  2. Primary Observations on the Influence of 60Co Local Irradiation on Free Skin Flaps

    Institute of Scientific and Technical Information of China (English)

    杨建荣; 张园

    2002-01-01

    Objective To study the effect of postoperative radiation on free skin flaps.Methods Twenty-nine patients with free skin flaps applied to the plerosis of the postoperative defectwere followed up. Twenty-eight out of 29 patients received forearm free flaps while 1 had anterolater-al femoris skin flaps in a size ranging from 14 cm× 6 cm to 8 cm× 4 cm. These flaps were exposedto 60Co radiation ranging 40-69 Gy. Results Observation during irradiation: no visible changes ofskin flaps and oral mucous membrane were detected when irradiation dose was within 40 Gy; somechanges may be detected over 40 Gy. Observation 1 - 4 months after irradiation: pigmentations werefound in areas of erosion epidermis; skin flaps got dark but without evidence of necrosis. Observation2 years after irradiation: no necrosis happened in 29 skin flaps. Hairs were found on 15 of 29flaps. Sensation occurred within the margin of 1 cm. Conclusion Free skin flap can endure irradi-ation at the dose of 60 Gy.

  3. Grafting of HEMA onto dopamine coated stainless steel by 60Coirradiation method

    Science.gov (United States)

    Jin, Wanqin; Yang, Liming; Yang, Wei; Chen, Bin; Chen, Jie

    2014-12-01

    A novel method for grafting of 2-hydroxyethyl methacrylate (HEMA) onto the surface of stainless steel (SS) was explored by using 60Coirradiation. The surface of SS was modified by coating of dopamine before radiation grafting. The grafting reaction was performed in a simultaneous irradiation condition. The chemical structures change of the surface before and after grafting was demonstrated by Fourier transform infrared (FTIR) spectrometer. The hydrophilicity of the samples was determined by water contact angle measurement in the comparison of the stainless steel in the conditions of pristine, dopamine coated and HEMA grafted. Surface morphology of the samples was characterized by atomic force microscope (AFM) and scanning electron microscope (SEM). The corrosion resistance properties of the samples were evaluated by Tafel polarization curve. The hemocompatibility of the samples were tested by platelet adhesion assay.

  4. ESR study of free radicals in UHMW-PE fiber irradiated by gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Zhao Yanning [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800 (China); College of Chemistry, Jilin Normal University, Jilin 136000 (China); Graduate University of the Chinese Academy of Sciences, Beijing 100049 (China); Wang Mouhua [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800 (China); Tang Zhongfeng [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800 (China); Graduate University of the Chinese Academy of Sciences, Beijing 100049 (China); Wu Guozhong, E-mail: wuguozhong@sinap.ac.c [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, PO Box 800-204, Shanghai 201800 (China)

    2010-04-15

    ESR spectra of the trapped radicals in an ultra-high molecular weight polyethylene (UHMW-PE) fiber irradiated by gamma rays showed well-resolved hyperfine splitting at room temperature since the c-axis of the crystallites is aligned with the fiber direction and the radicals are trapped in crystallites. The alkyl radical (-CH{sub 2}-{sup c}entre dotCH-CH{sub 2}-) was the major product after irradiation in vacuum and in air at room temperature. Some of the alkyl radicals converted to allyl radicals (-CH{sub 2}-{sup c}entre dotCH-CH=CH-) and polyenyl radicals (-CH{sub 2}-{sup c}entre dotCH-(CH=CH){sub n}-CH{sub 2}-) during storage in vacuum. Upon storage in air atmosphere, the alkyl radicals decayed by reaction with oxygen. Of particular interest is the very slow decay rate of the alkyl radical trapped in UHMW-PE fiber, the half-life is 26 days in vacuum, and 13 days in air at room temperature, which is about 1/30 and 1/100 of that reported for high density polyethylene (HDPE), respectively. The extremely long lifetime of the alkyl radical is supposed to be caused by the large size of crystallites in UHMW-PE fiber. The rate of radical decay was accelerated by annealing at elevated temperature.

  5. Dose calculation method with 60-cobalt gamma rays in total body irradiation

    CERN Document Server

    Scaff, L A M

    2001-01-01

    Physical factors associated to total body irradiation using sup 6 sup 0 Co gamma rays beams, were studied in order to develop a calculation method of the dose distribution that could be reproduced in any radiotherapy center with good precision. The method is based on considering total body irradiation as a large and irregular field with heterogeneities. To calculate doses, or doses rates, of each area of interest (head, thorax, thigh, etc.), scattered radiation is determined. It was observed that if dismagnified fields were considered to calculate the scattered radiation, the resulting values could be applied on a projection to the real size to obtain the values for dose rate calculations. In a parallel work it was determined the variation of the dose rate in the air, for the distance of treatment, and for points out of the central axis. This confirm that the use of the inverse square law is not valid. An attenuation curve for a broad beam was also determined in order to allow the use of absorbers. In this wo...

  6. EPR study of the formation of radicals in PP with antioxidants irradiated with gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Silva, P. [Instituto Venezolano de Investigaciones Cientificas, Centro de Fisica, Carretera Panamericana Km. 11, Caracas 1020-A (Venezuela)], E-mail: silva@ivic.ve; Albano, C. [Instituto Venezolano de Investigaciones Cientificas, Centro de Quimica, Universidad Central de Venezuela, Facultad de Ingenieria (Venezuela); Perera, R. [Departamento de Mecanica, Universidad Simon Bolivar (Venezuela)

    2007-12-15

    The behavior of different compounds of polypropylene (PP) with stabilizers such as buthyl-hydroxy-toluene (BHT), Chimassorb 944 (Hals) (CHIM), and a copolymer of styrene-butadiene-styrene (SBS) was studied using electron paramagnetic resonance (EPR). A characteristic spectra for pure PP irradiated in air was obtained for all the samples just after being irradiated [M. Dole, The Radiation Chemistry of Macromolecules, Vol. 2, Academic Press, 1973]. A change in the lineshape of the spectra from a pure PP's EPR signal to that of nitroxyl radical as a function of time was observed. The total free radical concentration (TFRC) decayed until approximately 800 h in the PP-HALS and until around 2000 h in all other cases, when the TFRC began to increase in all the cases, except in that of PP-BHT. In this last case, the EPR signal was not detectable after 4000 h. The BHT and the SBS diluted the free radical concentrations, being them smaller when they are present. The behavior observed in all the samples is consistent with the formation of nitroxyl radicals by gamma rays.

  7. Gamma 60Co-irradiation of organic matter in the Phosphoria Retort Shale

    Science.gov (United States)

    Lewan, M. D.; Ulmishek, G. F.; Harrison, W.; Schreiner, F.

    1991-04-01

    Irradiation experiments were conducted on a thermally immature rock sample of the Phosphoria Retort Shale and its isolated kerogen. A 60Co-source for gamma radiation was employed at dosages ranging from 81 to 885 Mrads, which are attainable by Paleozoic and Precambrian black shales with syngenetic uranium enrichments. Kerogen elemental, isotopic, and pyrolysate compositions are not affected at these dosages, but the bitumens extracted from the irradiated rock are affected. The major effects are reductions in the amounts of bitumen, acyclic isoprenoids, and high-molecular weight acyclic carboxylic acids. Natural differences in the amounts of bitumen and acyclic isoprenoid due to regional and stratigraphie variations in organic source input and depositional conditions make the radiation-induced reductions in these parameters difficult to use as indicators of natural radiation damage in black shales. However, the preferential reduction in the high-molecular weight acyclic carboxylic acids, which are ubiquitous in the living precursory organic matter, is diagnostic of experimental γ-irradiation but may not be diagnostic of natural irradiation. The overall process associated with radiation damage is polymerization by cross-linking through a free radical mechanism. As a result, irradiation of organic matter in black shales is more likely to retard rather than enhance petroleum generation.

  8. Comparison of the effects of gamma ray and e-beam irradiation on the quality of minced beef during storage

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae Nam; Han, In Jun; Kim, Wang Geun; Song, Beom Seok; Kim, Jae Hun; Choi, Jong Il; Yoon, Yo Han; Byun, Myung Woo; Hwang, Han Joon; Lee, Ju Woon [Korea Atomic Energy Research Institte, Jeongeup (Korea, Republic of); Park, Jin Gyu [Korea University, Seoul (Korea, Republic of)

    2009-06-15

    This study was conducted to compare the microbiological and physicochemical qualities of minced beef irradiated with gamma ray of e-beam at the absorbed doses from 5 to 20 kGy. The total bacterial counts of minced beef were decreased depending upon the irradiation doses, but sterilizing effect of gamma irradiation was higher than that of e-beam irradiation. The contents of malondialdegyde of minced beef were increased depending upon irradiation doses as well as storage periods (p< 0.05). Volatile basic nitrogen in minced beef was constantly increased during storage, but the increasing rate were retarded by irradiation. The hunter's color values(L*, a* and b*) of gamma or e-beam irradiated minced beef were decreased as irradiation dose increasing. Meanwhile, the quality changes of gamma irradiated samples were faster than e-beam irradiated samples.

  9. Effects of gamma-ray irradiation on electronic and non-electronic equipment of Large Helical Device

    Science.gov (United States)

    K, Ogawa; T, Nishitani; M, Isobe; M, Sato; M, Yokota; H, Hayashi; T, Kobuchi; T, Nishimura

    2017-02-01

    In a deuterium operation on the Large Helical Device, the measurement and control equipment placed in the torus hall must survive under an environment of radiation. To study the effects of gamma-ray irradiation on the equipment, an irradiation experiment is performed at the Cobalt-60 irradiation facility of Nagoya University. Transient and permanent effects on a personal computer, media converters, programmable logic controllers, isolation amplifiers, a web camera, optical flow meters, and water sealing gaskets are experimentally surveyed. Transient noise appears on the web camera. Offset of the signal increases with an increase of the integrated dose on the programmable logic controller. The DeviceNet module on the programmable logic controller is broken at the integrated dose of 72 Gy, which is the expected range of the integrated dose of the torus hall. The other equipment can survive under the gamma-ray field in the torus hall.

  10. Effects of gamma ray and electron-beam irradiations on survival of anaerobic and facultatively anaerobic bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Miyahara, Michiko; Miyahara, Makoto [National Inst. of Health Sciences, Tokyo (Japan)

    2002-10-01

    An extension of the approval for food irradiation is desired due to the increase in the incidence of food poisoning in the world. One anaerobic (Clostridium perfringens) and four facultatively anaerobic (Bacillus cereus, Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella Enteritidis) bacteria irradiated with gamma ray or electron beam (E-beam) were tested in terms of survival on agar under packaging atmosphere. Using pouch pack, effects of two irradiations on survival of anaerobic and facultatively anaerobic bacteria were evaluated comparatively. E-beam irradiation was more effective than gamma ray irradiation in decreasing the lethal dose 10% (D{sub 10}) value of B. cereus at 4 deg C, slightly more effective in that of E. coli O157, and similarly effective in that of the other three bacteria at 4 deg C. The gamma irradiation of the bacteria without incubation at 4 deg C before irradiation was more effective than that of the bacteria with incubation overnight at 4 deg C before irradiation in decreasing the D10 values of these bacteria (B. cereus, E. coli O157, and L. monocytogenes). Furthermore, ground beef patties inoculated with bacteria were irradiated with 1 kGy by E-beam (5 MeV) at 4 deg C. The inoculated bacteria in the 1-9 mm beef patties were killed by 1 kGy E-beam irradiation and some bacteria in more than 9 mm beef patties were not killed by the irradiation. (author)

  11. Stability Test For Sorghum Mutant Lines Derived From Induced Mutations with Gamma-Ray Irradiation

    Directory of Open Access Journals (Sweden)

    S. Human

    2011-12-01

    Full Text Available Sorghum breeding program had been conducted at the Center for the Application of Isotopes and Radiation Technology, BATAN. Plant genetic variability was increased through induced mutations using gamma-ray irradiation. Through selection process in successive generations, some promising mutant lines had been identified to have good agronomic characteristics with high grain yield. These breeding lines were tested in multi location trials and information of the genotypic stability was obtained to meet the requirements for officially varietal release by the Ministry of Agriculture. A total of 11 sorghum lines and varieties consisting of 8 mutant lines derived from induced mutations (B-100, B-95, B-92, B-83, B-76, B-75, B-69 and Zh-30 and 3 control varieties (Durra, UPCA-S1 and Mandau were included in the experiment. All materials were grown in 10 agro-ecologically different locations namely Gunungkidul, Bantul, Citayam, Garut, Lampung, Bogor, Anyer, Karawaci, Cianjur and Subang. In each location, the local adaptability test was conducted by randomized block design with 3 replications. Data of grain yield was used for evaluating genotypic stability using AMMI approach. Results revealed that sorghum mutation breeding had generated 3 mutant lines (B-100, B-76 and Zh-30 exhibiting grain yield significantly higher than the control varieties. These mutant lines were genetically stable in all locations so that they would be recommended for official release as new sorghum varieties to the Ministry of Agriculture

  12. Effect of {sup 60}Co gamma-irradiation on two-dimensional electron gas transport and device characteristics of AlGaN/GaN HEMTs

    Energy Technology Data Exchange (ETDEWEB)

    Umana-Membreno, G.A.; Dell, J.M.; Parish, G.; Nener, B.D.; Faraone, L. [School of Electrical, Electronic and Computer Engineering, The University ofWestern Australia, Crawley WA 6009 (Australia); Ventury, R.; Mishra, U.K. [Dept. of Electrical and Computer Engineering, University of California, Santa Barbara, CA 93106 (United States)

    2005-05-01

    The effect of {sup 60}Co gamma-irradiation on Al{sub 0.33}Ga{sub 0.67}N/GaN high-electron-mobility transistors (HEMTs) has been investigated using DC and geometrical magnetoresistance measurements. The devices studied were of similar epitaxial structure, yet differed in the doping levels of the Al{sub 0.33}Ga{sub 0.67}N barrier layer: (A) nominally undoped and (B) Si-doped with SiN{sub x} passivation. Exposure to cumulative gamma-ray doses up to 20 Mrad(Si) is shown to induce significant changes in drain-current level, threshold voltage and gate leakage current level. Analysis of magnetoresistance characteristics measured at 80 K indicated that irradiation induced an increase in two-dimensional electron-gas (2DEG) density, which leads to negative threshold voltage shifts observable in the drain current versus gate voltage characteristics, attributable to the introduction of defect centers in the Al{sub 0.33}Ga{sub 0.67}N layer and/or at the gate-AlGaN interface. The 2DEG mobility-concentration profiles are shown to remain approximately unchanged for doses up to 20 Mrad(Si). Device failure, evidenced as loss of gate control over the channel and/or excessive gate leakage, occurred after exposure to 30 Mrad(Si) for device A, whereas sample B failed after 20 Mrad(Si) total dose due to failure of half of the gate contact. Degradation of gate and source/drain contacts characteristics with total dose appears to limit the tolerance of the studied HEMTs to {sup 60}Co gamma-irradiation. (copyright 2005 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  13. Effect of gamma-ray irradiation on degradation of di(2-ethylhexyl)phthalate in polyvinyl chloride sheet.

    Science.gov (United States)

    Ito, Rie; Miura, Naoko; Ushiro, Masaru; Kawaguchi, Migaku; Nakamura, Hiroko; Iguchi, Hirofumi; Ogino, Jun-Ichi; Oishi, Manabu; Wakui, Nobuyuki; Iwasaki, Yusuke; Saito, Koichi; Nakazawa, Hiroyuki

    2009-07-01

    The risk assessment of di(2-ethylhexyl)phthalate (DEHP) migration from polyvinyl chloride (PVC) medical devices is an important issue for patients. The aim of this study was to determine DEHP degradation and migration from PVC sheets. To this end, the method for the simultaneous determination of DEHP and its breakdown products (mono(2-ethylhexyl)phthalate (MEHP) and phthalic acid (PA)) was improved. Their migration levels from 0 to 50 kGy gamma-ray irradiated PVC sheets were determined. DEHP migration level decreased in proportion to the dose of gamma-ray irradiation, while MEHP and PA migration levels increased. The hardness and the elastic modulus of PVC sheets were examined, but no clear relationship between DEHP migration and these parameters was observed.

  14. Effects of gamma-ray irradiation on optical properties of ZnO-PbO-B2O3 glasses

    DEFF Research Database (Denmark)

    Sharma, G.; Thind, K.S.; Manupriya, -;

    2006-01-01

    Effects of gamma-ray irradiation on some optical properties of xZnO(.)2xPbO(.)(1-3x)B2O3 glasses have been studied in the wavelength range 300-800 nm. Decrease in transmittance indicates the formation of color-center defects. Values for the energy-band gap, the width of the energy tail above the ...

  15. Prediction of cellular radiosensitivity from DNA damage induced by gamma-rays and carbon ion irradiation in canine tumor cells.

    Science.gov (United States)

    Wada, Seiichi; Van Khoa, Tran; Kobayashi, Yasuhiko; Funayama, Tomoo; Ogihara, Kikumi; Ueno, Shunji; Ito, Nobuhiko

    2005-11-01

    Diseases of companion animals are shifting from infectious diseases to neoplasms (cancer), and since radiation therapy is one of the effective choices available for cancer treatment, the application of radiotherapy in veterinary medicine is likely to increase. However tumor tissues have different radiosensitivities, and therefore it is important to determine the intrinsic radiosensitivity of tumors in individual patients in advance of radiotherapy. We have studied the relationship between the surviving cell fraction measured by a clonogenic assay and DNA double strand breaks detected by a comet assay under neutral conditions in three canine tumor cell lines, after gamma-ray and carbon ion irradiation. In all the cell lines, cell death assessed by the clonogenic assay was much higher following irradiation with carbon ions than with gamma-rays. The initial and residual (4 hr) DNA damage due to gamma-ray and carbon ion irradiation were higher in a radiosensitive cell line than in a radioresistant cell line. The surviving cell fraction at 2 Gy (SF2) showed a tendency for correlation with both the initial and residual DNA damage. In particular, the residual damage per Gy was significantly correlated with SF2, regardless of the type of radiation. This indicates that cellular radiosensitivity can be predicted by detection of radiation-induced residual DNA damage.

  16. Comparison of gamma ray and electron beam irradiation on extraction yield, morphological and antioxidant properties of polysaccharides from tamarind seed

    Science.gov (United States)

    Choi, Jong-il; Kim, Jae-Kyung; Srinivasan, Periasamy; Kim, Jae-Hun; Park, Hyun-Jin; Byun, Myung-Woo; Lee, Ju-Woon

    2009-07-01

    Tamarind ( Tamarindus indica L) seed polysaccharide (TSP) is of great important due to its various biological activities. The present investigation was carried out to compare extraction yield, morphological characteristics, average molecular weights and antioxidant activities of TSP from gamma- and electron beam (EB)-irradiated tamarind kernel powder. The tamarind kernel powder was irradiated with 0, 5 and 10 kGy by gamma ray (GR) and electron beam, respectively. The extraction yield of TSP was increased significantly by EB and GR irradiation, but there was no significant difference between irradiation types. Morphological studies by scanning electron microscope showed that TSP from GR-irradiated tamarind seed had a fibrous structure, different from that of EB irradiated with a particle structures. The average molecular weight of TSP was decreased by the irradiation, and EB treatment degraded more severely than GR. Superoxide radical scavenging ability and total antioxidant capacity of EB-treated TSP showed higher than those of GR-treated TSP.

  17. Comparison of gamma ray and electron beam irradiation on extraction yield, morphological and antioxidant properties of polysaccharides from tamarind seed

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jong-il [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Kim, Jae-Kyung [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Graduate school of Food and Biotechnology, Korea University, Seoul 146-701 (Korea, Republic of); Srinivasan, Periasamy; Kim, Jae-Hun [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Park, Hyun-Jin [Graduate school of Food and Biotechnology, Korea University, Seoul 146-701 (Korea, Republic of); Byun, Myung-Woo [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Lee, Ju-Woon [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of)], E-mail: sjwlee@kaeri.re.kr

    2009-07-15

    Tamarind (Tamarindus indica L) seed polysaccharide (TSP) is of great important due to its various biological activities. The present investigation was carried out to compare extraction yield, morphological characteristics, average molecular weights and antioxidant activities of TSP from gamma- and electron beam (EB)-irradiated tamarind kernel powder. The tamarind kernel powder was irradiated with 0, 5 and 10 kGy by gamma ray (GR) and electron beam, respectively. The extraction yield of TSP was increased significantly by EB and GR irradiation, but there was no significant difference between irradiation types. Morphological studies by scanning electron microscope showed that TSP from GR-irradiated tamarind seed had a fibrous structure, different from that of EB irradiated with a particle structures. The average molecular weight of TSP was decreased by the irradiation, and EB treatment degraded more severely than GR. Superoxide radical scavenging ability and total antioxidant capacity of EB-treated TSP showed higher than those of GR-treated TSP.

  18. Impaired colony-forming ability following. gamma. irradiation of skin fibroblasts from tuberous scierosis patients. [/sup 60/Co

    Energy Technology Data Exchange (ETDEWEB)

    Paterson, M.C.; Sell, B.M.; Smith, B.P.; Bech-Hansen, N.T.

    1982-05-01

    The radiosensitivity of cultured dermal fibroblasts from human subjects afflicted with tuberous sclerosis (TS), a hereditary neurocutaneous syndrome, was assessed by assaying loss of colony-forming ability in response to acute ..gamma..-ray exposure. Related to control strains from clinically normal donors, three cell lines (GM1635, GM1643, GM2333) from two affected patients displayed enhanced sensitivity to inactivation by /sup 60/Co ..gamma..-ray treatment, whether administered oxically (air-saturated) or hypoxically (N/sub 2/-gassed); a fourth strain (GM1644) from a third patient exhibited normal radiosensitivity under both treatment conditions. The post-..gamma..-irradiaton colony-forming ability of the three hypersensitive TS strains was intermediate between that of normal controls and that of strains from patients inheriting the radiotherapy-sensitive neurovascular disorder ataxia telangiectasia. The variability in the radioresponse of the TS stains (three sensitive and one normal) is not surprising, considering the widely recognized clinical heterogeneity in the disease. Our findings, aside from providing a laboratory marker for early (possible presymptomatic) detection of persons at high risk for TS, may lead to a better understanding of the origin and progressive development of this multifaceted syndrome.

  19. Production of acetic from ethanol solution by acetobactor acetigenum and effect of gamma-ray irradiation on the bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Umar, J.M. [National Atomic Energy Agency, Jakarta (Indonesia). Center for Application of Isotopes and Radiation; Matsuhashi, Shinpei; Hashimoto, Shoji

    1996-03-01

    A preliminary study on fermentation of acetic acid by S. cerevisiae and A. acetigenum was carried out to obtain information to develop the effective utilization technology of agricultural liquid wastes. Aqueous solutions of glucose and/or ethanol were used as a model of agricultural liquid waste. The effect of gamma-ray irradiation on A. acetigenum for enhancement of the fermentation was also examined. In this study, irradiated A. acetigenum had activity to produce acetic acid even after loss the activity to grow. (author).

  20. Radiation induced changes in electrical conductivity of chemical vapor deposited silicon carbides under fast neutron and gamma-ray irradiations

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, Bun, E-mail: btsuchiya@meijo-u.ac.jp [Department of General Education, Faculty of Science and Technology, Meijo University, 1-501, Shiogamaguchi, Tempaku-ku, Nagoya 468-8502 (Japan); Shikama, Tatsuo; Nagata, Shinji; Saito, Kesami [Institute for Materials Research, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai 980-8577 (Japan); Yamamoto, Syunya [Takasaki Advanced Radiation Research Institute, Japan Atomic Energy Agency, 1233, Watanuki-machi, Takasaki, Gunma 370-1292 (Japan); Ohnishi, Seiki [Tokai Research and Development Center, Japan Atomic Energy Agency, Tokai-mura, Naka-gun, Ibaraki 319-1195 (Japan); Nozawa, Takashi [Aomori Research and Development Center, Japan Atomic Energy Agency, 2-166, Omotedate, Obuchi, Rokkasho, Aomori 039-3212 (Japan)

    2011-10-15

    The radiation-induced changes in the volume electrical conductivities of chemical vapor deposited silicon carbides (CVD-SiCs) were in-site investigated by performing irradiation using 1.17 and 1.33-MeV gamma-ray and 14-MeV fast neutron beams in air and vacuum. Under gamma-ray irradiation at ionization dose rates of 3.6 and 5.9 Gy/s and irradiation temperature of approximately 300 K, the initial rapid increase in electrical conductivity; this is indicative of radiation-induced conductivity (RIC), occurred due to electronic excitation, and a more gradual increase followed up to a dose of approximately 10-50 kGy corresponding to the results in base conductivity without radiation; this is indicative of radiation-induced electrical degradation (RIED). However, the radiation-induced phenomena were not observed at irradiation temperatures above 373 K. Under neutron irradiation at a further low dose rate below approximately 2.1 Gy/s, a fast neutron flux of 9.2 x 10{sup 14} n/m{sup 2} s, and 300 K, the RIED-like behavior according to radiation-induced modification of the electrical property occurred with essentially no displacement damage, but ionizing effects (radiolysis).

  1. Detection and thermoluminescence of coriander (Coriandrum sativum L.) irradiated with {sup 60}Co; Deteccion y termoluminiscencia del cilantro (Coriandrum sativum L.) irradiado con {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz G, B. [Departamento de Agricultura y Ganaderia, Universidad de Sonora, 083190 Hermosillo, Sonora (Mexico); Cruz Z, E. [Unidad de Irradiacion y Seguridad Radiologica, Instituto de Ciencias Nucleares, UNAM, A. P. 70-543, 04510 Mexico D. F. (Mexico); Barboza F, M. [Centro de Investigacion en Fisica, Universidad de Sonora, A. P. 5-088, 083190 Hermosillo, Sonora (Mexico)

    2009-10-15

    The fresh and dried coriander (Coriandrum sativum L.) is a spice of high commercial value as food for consumption in Mexico. Their hygienic quality is often poor due to some factors: contaminants present in irrigation water and the cultivation atmosphere, harvesting and post harvest handling, mainly. The process by radiation is an alternative to achieve the sterilization to adequate dose for the hygienic quality for its consumption. However, irradiation also involves food detection exposed to radiation. This paper presents detected results on the dried coriander that was obtained from fresh samples and thermoluminescent properties such as glow curves structure from low doses (0.5 Gy) to high (15 kGy), the dose response, thermoluminescent signal decay, in order to determine the loss of stability during the storage of the poly mineral fraction. We obtained the inorganic fraction separation of the organic part of particle sizes of 10 {mu}m by the Zimmerman method. The samples were exposed at two dose ranges; 0.5-400 Gy and 0.5-15 kGy of gamma radiation with {sup 60}Co. The limit of thermoluminescent detection of the irradiated coriander samples was from 1 Gy. The glow curves were at a broad band of 35-400 C, with a maximum thermoluminescence around 182-196 C, and run at 164 C for high doses of 15 kGy. The range of linear response to dose was 4-25 Gy, whereas higher doses than the kGy order the response increase with the dose. The thermoluminescent properties of the coriander poly mineral fraction, show it can be used to identify irradiated food at gamma doses relatively low and even in doses of commercial interest due to the high stability of thermoluminescent signals. (Author)

  2. Pregnancy-dependent initiation in tumorigenesis of Wistar rat mammary glands by sup 60 Co-irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Inano, Hiroshi; Suzuki, Keiko; Ishii-Ohba, Hiroko; Ikeda, Kiyomi (National Inst. of Radiological Sciences, Chiba (Japan)); Wakabayashi, Katsumi (Gunma Univ., Maebashi (Japan). Hormone Assay Center)

    1991-06-01

    Pregnant Wistar rats received whole body irradiation with 260 cGy {gamma}-rays at days 7, 14 and 20 of pregnancy and then were treated with diethylstilbestrol (DES) for 1 year. The highest incidence (92.9%) for tumorigenesis of mammary glands was observed in the rats irradiated in late pregnancy. Histological examination showed that tumors were classified as fibroadenoma and adenocarcinoma. To determine the reasons for specific induction of mammary tumors by irradiation in late pregnancy, hormone concentrations in serum and estrogen receptors in mammary glands during pregnancy were measured. Concentrations of estradiol, progesterone, 11-deoxycorticosterone and placental lactogen at day 20 were higher than at days 7 and/or 14, but no difference was observed in the concentrations of prolactin and thyroid-stimulating hormone during pregnancy. The estrogen receptor in mammary glands at day 20 was indicated to have the highest affinity and the highest binding capacity during pregnancy. Normal mammary glands at day 20 were suggested to have more abundant epithelial cells in the mammary lobes than those at days 7 and 14. The data suggest that the critical requirements for the initiation of tumorigenesis by {gamma}-rays are dependent upon the differentiated state of mammary glands exposed to various hormones, and that the concentration and persistence of the synthetic estrogen (DES) are necessary for the promotion of tumorigenesis of the irradiated mammary glands. (Author).

  3. 60CoIrradiation Affects the Enzymatic Antioxidant System of the Citrus Red Mite Panonychus citri (Acari: Tetranychidae

    Directory of Open Access Journals (Sweden)

    Ke Zhang

    2014-05-01

    Full Text Available Radio-(60Co, which emits γ rays, has been used worldwide in pest control. The aim of the present study was to analyze the effect of effective-low-power 60Coirradiation on the enzymatic antioxidant system of the citrus red mite Panonychus citri. One day old female adults were exposed to 0.4 kGy 60Coirradiation and on the, 6th h, 1st day, 2nd day, and 5th day post treatment, the mites were euthanized for biochemical analysis. The activity of superoxide dismutase (SOD, catalase (CAT, peroxidase (POD, phenoloxidase (PO and acetylocholinesterase (AchE were investigated. POD and CAT activities, as well as SOD were higher in the irradiated mites. We found that exposure to 60Co-γ radiation resulted in increased activities of SOD, CAT, POD and decreased AchE activity. When the recovery time lasted till the 5th day, the activities of POD and PO were significantly lower than the control, whereas the SOD, CAT and AchE activities returned to control levels. Cells possess protein repair pathways to rescue oxidized proteins and restore their functions, but if these repair processes fail, oxidized proteins may become cytotoxic. Our results confirm the hypothesis that low dosages of 60Coirradiation increase the level of oxidative stress in P. citri adults in a short time, causing meanwhile damage and sterility. The results of this study also indicate that stress caused by exposure to irradiation could inhibit the cholinergic system in P. citri.

  4. Viabilidade e micoflora de sementes de amendoim irradiadas com cobalto (60Co Viability and mycoflora of irradiated seeds of peanut with cobalt (60Co

    Directory of Open Access Journals (Sweden)

    Niédja M. C. Alves

    2011-03-01

    Full Text Available Estudou-se o efeito de diferentes doses da irradiação gama na germinação e percentagem de infecção fúngica em sementes de amendoim cultivar BR1. Inicialmente, as sementes foram avaliadas quanto à micoflora, utilizando-se o método de papel de filtro umedecido, a germinação em substrato de papel germitest e determinação do teor de umidade em estufa, a 105 ± 2 ºC. Posteriormente, as sementes foram submetidas à irradiação com uma fonte de 60Co, tipo gammacell, onde se estudou o efeito de 8 doses de irradiação na micoflora e germinação das sementes acondicionadas em embalagem de PET e polietileno trançado durante 60 dias de armazenamento, sem controle de temperatura e umidade relativa do ar. Os fatores estudados (doses em kGy, embalagens e tempo de armazenamento foram analisados em um delineamento inteiramente casualizado, dispostos em fatorial. Com base nos resultados, observou-se que a irradiação gama afetou negativamente a germinação das sementes de amendoim e que doses acima de 3,0 kGy comprometem a germinação das sementes. A radiação a partir da dose 1,5 kGy eliminou os fungos Aspergillus niger e, Penicillium a partir da dose de 2,5 kGy.The effect of different doses of the gamma irradiation was studied on germination and percentage of fungal infection in peanut seeds cultivar BR1. Initially the seeds were evaluated for the mycoflora using the method of humidified filter paper, the germination in paper substratum germitest and determination of the moisture content in oven at 105 ± 2 ºC. Later on the seeds were submitted to irradiation with a source of 60Co, type gammacell, where the effect was studied of 8 doses of irradiation in the mycoflora and germination of the seeds conditioned in PET packing and polyethylene tressed during 60 days of storage, without control of temperature and relative humidity of the air. The studied factors (doses in kGy, packing and time of storage were analyzed in a completely

  5. Evaluation of induced radioactivity in 10 MeV-electron irradiated spices, (1); [gamma]-ray measurement

    Energy Technology Data Exchange (ETDEWEB)

    Furuta, Masakazu; Katayama, Tadashi; Ito, Norio; Mizohata, Akira; Matsunami, Tadao; Shibata, Setsuko; Toratani, Hirokazu (Osaka Prefectural Univ., Sakai (Japan). Research Inst. for Advanced Science and Technology); Takeda, Atsuhiko

    1994-02-01

    Black pepper, white pepper, red pepper, ginger and turmeric were irradiated with 10 MeV electrons from a linear accelerator to a dose of 100 kGy and radioactivity was measured in order to estimate induced radioactivity in the irradiated foods. Induced radioactivity could not be detected significantly by [gamma]-ray spectrometry in the irradiated samples except for spiked samples which contain some photonuclear target nuclides in the list of photonuclear reactions which could produce radioactivity below 10 MeV. From the amount of observed radioactivities of short-lived photonuclear products in the spiked samples and calculation of H[sub 50] according to ICRP Publication 30, it was concluded that the induced radioactivity and its biological effects in the 10 MeV electron-irradiated natural samples were negligible in comparison with natural radioactivity from [sup 40]K contained in the samples. (author).

  6. Gamma-ray irradiation and post-irradiation at room and elevated temperature response of pMOS dosimeters with thick gate oxides

    Directory of Open Access Journals (Sweden)

    Pejović Momčilo M.

    2011-01-01

    Full Text Available Gamma-ray irradiation and post-irradiation response at room and elevated temperature have been studied for radiation sensitive pMOS transistors with gate oxide thickness of 100 and 400 nm, respectively. Their response was followed based on the changes in the threshold voltage shift which was estimated on the basis of transfer characteristics in saturation. The presence of radiation-induced fixed oxide traps and switching traps - which lead to a change in the threshold voltage - was estimated from the sub-threshold I-V curves, using the midgap technique. It was shown that fixed oxide traps have a dominant influence on the change in the threshold voltage shift during gamma-ray irradiation and annealing.

  7. [Effects of 25 Gy gamma-ray irradiation on the expression of CD62p in manually enriched human platelets].

    Science.gov (United States)

    Zhao, Lin-Na; Zhao, Hong-Sheng; Li, Jian-Bin; Shan, Hong; Han, Xiao-Gai; Jiao, Hong-Liang

    2010-04-01

    This study was purposed to investigate the effects of 25 Gy gamma-ray irradiation on the CD62p expression, platelet count and the mean platelet volume (MPV) of manually enriched platelet suspension in different time of shelf life at 22 degrees C. Each of 16 bags with plasma-rich platelet was divided into two bags, one of which was exposed to 25 Gy gamma-ray of 137Cs and the other ones was not exposed. 16 bags then were preserved for 72 hours according to AABB standards. The irradiated platelets were regarded as the observation group, and the other ones were regarded as the control group, the expression of p-selectin (CD62p) in the above 2 groups was detected by flow cytometry before irradiation and at 24, 72 hours after irradiation respectively; at the same time, the platelet count and MPV were assayed by using blood cell counter. The results showed that the expression level of CD62p on platelet in irradiated and control groups increased along with the prolonging of preservation time, the expression rate of CD62p on the platelets preserved for 24 hours was higher than that on fresh platelets with significant difference (pplatelets preserved for 72 hours obviously was enhanced as compared with platelets preserved for 24 hours (pplatelet count and MPV between irradiated and control groups preserved for 24 and 72 hours (p>0.05), however the MPV of irradiated and control groups preserved for 72 hours was higher than that of fresh platelets (pquality of platelets, but the preservation time for manually enriched platelet suspension should be shortened as far as possible.

  8. Influence of Gamma-Ray Irradiation on Absorption and Fluorescent Spectra of Nd:YAG and Yb:YAG Laser Crystals

    Institute of Scientific and Technical Information of China (English)

    SUN Dun-Lu; ZHANG Qing-Li; XIAO Jing-Zhong; LUO Jian-Qiao; JIANG Hai-He; YIN Shao-Tang

    2008-01-01

    We investigate the influence of gamma-ray irradiation on the absorption and fluorescent spectra of Nd3+ : Y3Al5O12 (Nd:YAG) and Yb3+ :Y3Al5O12 (Yb:YAG) crystals grown by the Czochralski method. Two additional absorption (AA) bands induced by gamma-ray irradiation appear at 255nm and 340nm. The former is eontributed due to Fe3+ impurity, the latter is due to Fe2+ ions and F-type colour centres. The intensity of the excitation and emission spectra as well as the fluorescent lifetime of Nd:YAG crystal decrease after the irradiation of 100 Mrad gamma-ray. In contrast, the same dose irradiation does not impair the fluorescent properties of Yb: YA G crystal. These results indicate that Yb: YA G crystal possesses the advantage over Nd: YA G crystal that has better reliability for applications in harsh radiant environment.

  9. Monte Carlo simulation of prompt gamma-ray spectra from depleted uranium under D-T neutron irradiation and electron recoil spectra in a liquid scintillator detector

    CERN Document Server

    Qin, Jianguo; Liu, Rong; Zhu, Tonghua; Zhang, Xinwei; Ye, Bangjiao

    2015-01-01

    To overcome the problem of inefficient computing time and unreliable results in MCNP5 calculation, a two-step method is adopted to calculate the energy deposition of prompt gamma-rays in detectors for depleted uranium spherical shells under D-T neutrons irradiation. In the first step, the gamma-ray spectrum for energy below 7 MeV is calculated by MCNP5 code; secondly, the electron recoil spectrum in a BC501A liquid scintillator detector is simulated based on EGSnrc Monte Carlo Code with the gamma-ray spectrum from the first step as input. The comparison of calculated results with experimental ones shows that the simulations agree well with experiment in the energy region 0.4-3 MeV for the prompt gamma-ray spectrum and below 4 MeVee for the electron recoil spectrum. The reliability of the two-step method in this work is validated.

  10. Manufacture of Single 60Co Source Irradiation Facility and the Measurement of Reference Radiation Filed

    Institute of Scientific and Technical Information of China (English)

    GAO; Fei; WANG; Hong-yu; NI; Ning; ZHANG; Li; HOU; Jin-bing; SONG; Ming-zhe

    2012-01-01

    <正>Reference radiation filed produced by isotope source is necessary for calibration of radiation dose meter. 60Co single source radiation facility is an important method to produce reference radiation. Collimation design of the facility is good for characteristics of the field, but there are scattered photon influences however. Scattered radiation is mainly come from collimation, source shield, floor, walls and

  11. On-Line High Dose-Rate Gamma Ray Irradiation Test of the CCD/CMOS Cameras

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jai Wan; Jeong, Kyung Min [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    In this paper, test results of gamma ray irradiation to CCD/CMOS cameras are described. From the CAMS (containment atmospheric monitoring system) data of Fukushima Dai-ichi nuclear power plant station, we found out that the gamma ray dose-rate when the hydrogen explosion occurred in nuclear reactors 1{approx}3 is about 160 Gy/h. If assumed that the emergency response robot for the management of severe accident of the nuclear power plant has been sent into the reactor area to grasp the inside situation of reactor building and to take precautionary measures against releasing radioactive materials, the CCD/CMOS cameras, which are loaded with the robot, serve as eye of the emergency response robot. In the case of the Japanese Quince robot system, which was sent to carry out investigating the unit 2 reactor building refueling floor situation, 7 CCD/CMOS cameras are used. 2 CCD cameras of Quince robot are used for the forward and backward monitoring of the surroundings during navigation. And 2 CCD (or CMOS) cameras are used for monitoring the status of front-end and back-end motion mechanics such as flippers and crawlers. A CCD camera with wide field of view optics is used for monitoring the status of the communication (VDSL) cable reel. And another 2 CCD cameras are assigned for reading the indication value of the radiation dosimeter and the instrument. In the preceding assumptions, a major problem which arises when dealing with CCD/CMOS cameras in the severe accident situations of the nuclear power plant is the presence of high dose-rate gamma irradiation fields. In the case of the DBA (design basis accident) situations of the nuclear power plant, in order to use a CCD/CMOS camera as an ad-hoc monitoring unit in the vicinity of high radioactivity structures and components of the nuclear reactor area, a robust survivability of this camera in such intense gamma-radiation fields therefore should be verified. The CCD/CMOS cameras of various types were gamma irradiated at a

  12. Volatile compounds and odor traits of dry-cured ham (Prosciutto crudo) irradiated by electron beam and gamma rays

    Science.gov (United States)

    Kong, Qiulian; Yan, Weiqiang; Yue, Ling; Chen, Zhijun; Wang, Haihong; Qi, Wenyuan; He, Xiaohua

    2017-01-01

    Prosciutto crudo samples were irradiated at 0, 3 and 6 kGy by gamma rays (GR) and electron beam (EB), respectively. The odor scores and volatile compounds were examined after 7 days storage at 4 °C. Volatile compounds from samples without and with irradiation at 6 kGy were analyzed by GC-MS. Fifty-nine compounds were identified, including terpenes, aldehydes, alcohols, ketones, alkanes, esters, aromatic hydrocarbons and acids. Both GR and EB irradiation resulted in formation of (Z)-7-Hexadecenal, cis-9-hexadecenal, tetradecane, E-9-tetradecen-1-ol formate, and losing of hexadecamethyl-heptasiloxane and decanoic acid-ethyl ester in hams. However, GR irradiation caused additional changes, such as formation of undecane and phthalic acid-2-cyclohexylethyl butyl ester, significantly higher level of 1-pentadecene, and losing of (E, E)-2,4-decadienal and octadecane. EB was shown to be better in maintaining ham's original odor than GR. Our results suggest that EB irradiation is a promising method for treatment of ready to eat hams as it exerts much less negative effect on the flavor of hams compared to GR irradiation.

  13. Investigation of photoneutron and capture gamma-ray production in Pb and W under irradiation from 16N decay radiation

    Science.gov (United States)

    Kebwaro, Jeremiah Monari; Zhao, Yaolin; He, Chaohui

    2015-09-01

    Lead and tungsten are potential alternative materials for shielding reactor ex-core components with high 16N activity when available space limits application of concrete. Since the two materials are vulnerable to photonuclear reactions, the nature and intensity of the secondary radiation resulting from (γ,n) and (n,γ) reactions when 16N decay radiation interact with these materials need to be well known for effective shielding design. In this study the MCNP code was used to calculate the photoneutron and capture gamma-ray spectra in the two materials when irradiated by 16N decay radiation. It was observed that some of the photoneutrons generated in the two materials lie in the low-energy range which is considered optimum for (n,γ) reactions. Lead is more transparent to the photoneutrons when compared to tungsten. The calculations also revealed that the bremsstrahlung generated by the beta spectrum was not sufficient to trigger any additional photoneutrons. Both energetic and less energetic capture gamma-rays are observed when photoneutrons interact with nuclei of the two materials. Depending on the strength of the 16N source term, the secondary radiation could affect the effectiveness of the shield and need to be considered during design.

  14. Action of Bothrops moojeni venom and its L-amino acid oxidase fraction, treated with {sup 60}Co gamma rays, in Leishmania spp; Acao do veneno de Bothrops moojeni e sua fracao L-aminoacido oxidase, submetida ao tratamento com raios gama de {sup 60}Co, em Leishmania spp

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Andre Gustavo Tempone

    1999-07-01

    Bothrops moojeni venom showed an anti leishmania activity in vitro, as determined by a cell viability assay using the reduction of MTT. After venom purification, by chromatography techniques, the fractions with anti leishmania and L-amino acid oxidase activities, eluted in the same positions. The molecular weight of the enzyme was estimated to be 140 kDa by molecular exclusion chromatography, and 69 kDa, by SDS-PAGE, migrating as a single band, with an isoelectric point of 4.8 as determined by isoelectric focusing. The purified LAO from B. moojeni venom, 135-fold more active than crude venom, showed homo dimeric constitution, and was active against Leishmania spp from the New World, with an effective concentration against L(L). amazonensis of 1.80 {mu}g/ml (EC{sub 50}), L.(V.) panamensis (0.78 |{mu}g/ml) and L.(L.) chagasi (0.63 ({mu}g/ml). Ultrastructural studies of promastigotes affected by LAO demonstrated cell death, with edema in several organelles such as mitochondria and nuclear membrane, before cell disruption and necrosis. The action of LAO was demonstrated to be hydrogen peroxide-dependent. Studies with LLCMK-2 cells, treated with LAO, showed a toxic effect, with an EC{sub 50} of 11|{mu}g/ml. Irradiation of LAO with 6{sup 0C}o gamma rays, did not affect its whole oxidative activity, neither detoxified the enzyme. Amastigotes treated with LAO were not affected by its hydrogen peroxide, otherwise, the exogenous product, killed amastigotes with an EC{sub 50} of 0.67mM. These data could be of help in the development of alternative therapeutic approaches to the treatment of leishmaniasis. (author)

  15. Selection and characterization of tomato plants for osmotic stress tolerance derived from a gamma ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Kwon Kyoo; Jung, Yu Jin [Hankyong National University, Anseong (Korea, Republic of)

    2010-09-15

    The present study has been performed to select the osmotic tolerant lines using polyethylene glycol (PEG 6000)through an in vitro and in vivo mutagensis with a gamma-ray. During the screening, we selected three mutant lines that seemed to confer elevated osmotic tolerance in high concentrations of PEG 6000. Fruits of these mutants (Os-HK101, Os-HK102 and Os-HK103) were those of the wild type. Also the chlorophyll contents were few decreased more in the three mutant lines than the WT plants. Our results suggest that the Os-HK101 is characterized as osmotic stress tolerance considering the sugar concentration and lycopine content. It is expected that the result of this study can be used for breeding more competitive species with respect to contents in sugar or functional chemicals from the selected osmotic resistant lines.

  16. Topological and morphological analysis of gamma rays irradiated chitosan-poly (vinyl alcohol) blends using atomic force microscopy

    Science.gov (United States)

    Bhatt, Rinkesh; Bisen, D. S.; Bajpai, R.; Bajpai, A. K.

    2017-04-01

    In the present communication, binary blends of poly (vinyl alcohol) (PVA) and chitosan (CS) were prepared by solution cast method and the roughness parameters of PVA, native CS and CS-PVA blend films were determined using atomic force microscopy (AFM). Moreover, the changes in the morphology of the samples were also investigated after irradiation of gamma rays at absorbed dose of 1 Mrad and 10 Mrad for the scanning areas of 5×5 μm2, 10×10 μm2 and 20×20 μm2. Amplitude, statistical and spatial parameters, including line, 3D and 2D image profiles of the experimental surfaces were examined and compared to un-irradiated samples. For gamma irradiated CS-PVA blends the larger waviness over the surface was found as compared to un-irradiated CS-PVA blends but the values of average roughness for both the films were found almost same. The coefficient of skewness was positive for gamma irradiated CS-PVA blends which revealed the presence of more peaks than valleys on the blend surfaces.

  17. Morphological and histological studies on freshwater prawn Macrobrachium rosenbergii (de man) irradiated with {sup 60}Co gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Stalin, A.; Broos, K.V. [P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu (India); Sadiq Bukhari, A., E-mail: abjmc@yahoo.in [P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu (India); Syed Mohamed, H.E. [P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu (India); Singhal, R.K. [Analytical Spectroscopy Section, Analytical Chemistry Division, Bhabha Atomic Research Center, Trombay, Mumbai 4000085 (India); Venu-Babu, P. [Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Center, Trombay, Mumbai 4000085 (India)

    2013-11-15

    Graphical abstract: -- Highlights: •Analyzing the impact of {sup 60}Co gamma radiation (low doses) in M. rosenbergii. •LD{sub 50} identified in 30 Gy; Irradiated exhibits morphological changes than control. •Significantly decreased HSI and histological changes in irradiated groups. •Aberration severities increased as increased of dose level. •Biomonitoring tool in determining low dose radiation pollution in aquatic ecosystem. -- Abstract: This study was framed to investigate the {sup 60}Co gamma radiation induced morphological and histological variations in freshwater prawn Macrobrachium rosenbergii. The LD{sub 50} value of {sup 60}Co gamma irradiated M. rosenbergii observed (by probit analysis) at 30 Gy. Prawns were irradiated to four different dose levels (3 mGy, 30 mGy, 300 mGy and 3000 mGy) using Theratron Phoenix TeleCobalt Unit [P-33] and one control group (without irradiation) maintained separately. Irradiated groups exhibited several morphological variations such as discoloration; damaged rostrum; opaque coloration in cephalothorax; black bands and dot formation in abdomen; deformed uropods and telson in tail regions when compared with control group. The Hepato Somatic Index reflected the severity of radiation on hepatopancreas. Histological variations in gills, hepatopancreas and muscles of irradiated groups were observed. In gills, structural changes such as swollen and fused lamellae, abnormal gill tips, hyperplasic, necrotic and clavate-globate lamellae were observed in gamma irradiated prawns. Accumulation of hemocytes in hemocoelic space, interstitial sinuses filled with abnormal infiltrated hemocytes, the tubular epithelium with ruptured basal laminae, abnormal and coagulated lumen, necrotic tubules, thickened basal laminae, tissue debris, necrotic hepatocytes were observed in irradiated prawn hepatopancreas. In muscle, shrinkage of muscular fiber and necrotic musculature were observed in irradiated prawns. These structural alterations of

  18. Morphological and histological studies on freshwater prawn Macrobrachium rosenbergii (de man) irradiated with (60)Co gamma radiation.

    Science.gov (United States)

    Stalin, A; Broos, K V; Sadiq Bukhari, A; Syed Mohamed, H E; Singhal, R K; Venu-Babu, P

    2013-11-15

    This study was framed to investigate the (60)Co gamma radiation induced morphological and histological variations in freshwater prawn Macrobrachium rosenbergii. The LD50 value of (60)Co gamma irradiated M. rosenbergii observed (by probit analysis) at 30 Gy. Prawns were irradiated to four different dose levels (3 mGy, 30 mGy, 300 mGy and 3,000 mGy) using Theratron Phoenix TeleCobalt Unit [P-33] and one control group (without irradiation) maintained separately. Irradiated groups exhibited several morphological variations such as discoloration; damaged rostrum; opaque coloration in cephalothorax; black bands and dot formation in abdomen; deformed uropods and telson in tail regions when compared with control group. The Hepato Somatic Index reflected the severity of radiation on hepatopancreas. Histological variations in gills, hepatopancreas and muscles of irradiated groups were observed. In gills, structural changes such as swollen and fused lamellae, abnormal gill tips, hyperplasic, necrotic and clavate-globate lamellae were observed in gamma irradiated prawns. Accumulation of hemocytes in hemocoelic space, interstitial sinuses filled with abnormal infiltrated hemocytes, the tubular epithelium with ruptured basal laminae, abnormal and coagulated lumen, necrotic tubules, thickened basal laminae, tissue debris, necrotic hepatocytes were observed in irradiated prawn hepatopancreas. In muscle, shrinkage of muscular fiber and necrotic musculature were observed in irradiated prawns. These structural alterations of the organs it is felt could affect the vital physiological functions such as respiration, osmotic and ionic regulation in gills and muscles; absorption, storage and secretion of the hepatopancreas which in turn could adversely affect the growth and survival of freshwater prawn M. rosenbergii.

  19. Chromosome aberrations and micronucleus in continuously irradiated mice for a low dose rate of {sup 137}Cs {gamma}-rays

    Energy Technology Data Exchange (ETDEWEB)

    Izumi, Jun; Yanai, Takanori; Shirata, Katsutoshi; Tanaka, Kimio; Sato, Fumiaki [Inst. for Environmental Sciences, Rokkasho, Aomori (Japan)

    2002-07-01

    Delayed chromosomal instability is developed by radiation after several cell divisions in cultured rodent and human cells. The genetic instability might be related to cancer development and it has been mainly found in cultured rodent and human cells irradiated at high dose rate. It has not been well studied whether the genetic instability is induced by prolonged irradiation with low dose rate in vivo or not. Mice irradiated with 20 mGy/day for 5-8 Gy were analyzed by FISH to estimate the chromosome aberration rate and micronucleus incidence in spleen and bone marrow cells. Spleen cells in mice exposed to 8 Gy have higher incidence of monosomy and trisomy than non-exposed mice. The number of cells with 2-4 micronuclei in 10,000 scored spleen cells is also higher in 5-8 Gy exposed mice. These numerical chromosome aberrations are not induced directly by radiation exposure. These results indicate that prolonged {sup 137}Cs {gamma} ray-irradiation with low dose rates of 20 mGy/day induces delayed chromosome instability in mice. (author)

  20. Effects of (60)Co gamma irradiation on behavior and gill histoarchitecture of giant fresh water prawn Macrobrachium rosenbergii (DE MAN).

    Science.gov (United States)

    Stalin, A; Broos, K V; Sadiq Bukhari, A; Syed Mohamed, H E; Singhal, R K; Venu-babu, P

    2013-06-01

    Present study was designed to observe the effects of (60)Co gamma radiation in behavioral and histological changes in the gills of giant fresh water prawn Macrobrachium rosenbergii. The adult prawns were irradiated with four different dose levels (3mGy, 30mGy, 300mGy and 3000mGy) and the control group (without irradiation) was maintained separately. Behavioral changes like hyperactivity, loss of balance, reduced swimming rate, slower rate of food intake and convulsions were observed in higher dose levels of 300mGy and 3000mGy. The histological alterations such as accumulated haemocytes in haemocoelic spaces, abnormal gill tips, lifted lamellar epithelium, swollen and fused lamellae, hyperplasic, necrotic, clavate-globate and complete disorganization of lamellae were observed in (60)Co gamma irradiated prawns. Significantly more considerable histological alterations were observed in the highest dose level of 3000mGy, but no mortality was evidenced. This study serves as biomonitoring tool to assess the radiation pollution in the aquatic environment.

  1. 60Co γ辐照对西红花发育的影响%EFFECTS OF 60 Co γ-IRRADIATION ON DEVELOPMENT OF Crocus sativus L

    Institute of Scientific and Technical Information of China (English)

    赵军; 陈晓斌; 陈放

    2006-01-01

    本文利用剂量为5~25Gy的60Co γ射线,对重12~14g的西红花球茎进行辐照处理,研究辐照对西红花开花、花器官发育和球茎再生等方面的影响.结果显示:辐照处理对西红花开花有刺激作用;5~10Gy为西红花的最适诱变剂量.

  2. DNA repair in modeled microgravity: Double strand break rejoining activity in human lymphocytes irradiated with {gamma}-rays

    Energy Technology Data Exchange (ETDEWEB)

    Mognato, Maddalena, E-mail: maddalena.mognato@unipd.it [Dipartimento di Biologia, Universita di Padova, via U. Bassi 58 B, 35121 Padova (Italy); Girardi, Cristina; Fabris, Sonia [Dipartimento di Biologia, Universita di Padova, via U. Bassi 58 B, 35121 Padova (Italy); Celotti, Lucia [Dipartimento di Biologia, Universita di Padova, via U. Bassi 58 B, 35121 Padova (Italy); Laboratori Nazionali di Legnaro, INFN, Padova (Italy)

    2009-04-26

    Cell response to ionising radiation depends, besides on genetic and physiological features of the biological systems, on environmental conditions occurring during DNA repair. Many data showed that microgravity, experienced by astronauts during space flights or modeled on Earth, causes apoptosis, cytoskeletal alteration, cell growth inhibition, increased frequency of mutations and chromosome aberrations. In this study, we analysed the progression of the rejoining of double strand breaks (DSBs) in human peripheral blood lymphocytes (PBLs) irradiated with {gamma}-rays and incubated in static condition (1g) or in modeled microgravity (MMG). {gamma}-H2AX foci formation and disappearance, monitored during the repair incubation, showed that the kinetics of DSBs rejoining was different in the two gravity conditions. The fraction of foci-positive cells decreased slower in MMG than in 1g at 6 and 24 h after irradiation (P < 0.01) and the mean number of {gamma}-H2AX foci per nucleus was significantly higher in MMG than in 1g at the same time-points (P < 0.001). In the same samples we determined apoptotic level and the rate of DSB rejoining during post-irradiation incubation. A significant induction of apoptosis was observed in MMG at 24 h after irradiation (P < 0.001), whereas at shorter times the level of apoptosis was slightly higher in MMG respect to 1g. In accordance with the kinetics of {gamma}-H2AX foci, the slower rejoining of radiation-induced DSBs in MMG was observed by DNA fragmentation analyses during the repair incubation; the data of pulsed-field gel electrophoresis assay showed that the fraction of DNA released in the gel was significantly higher in PBL incubated in MMG after irradiation with respect to cells maintained in 1g. Our results provide evidences that MMG incubation during DNA repair delayed the rate of radiation-induced DSB rejoining, and increased, as a consequence, the genotoxic effects of ionising radiation.

  3. Irradiation with low-dose gamma ray enhances tolerance to heat stress in Arabidopsis seedlings.

    Science.gov (United States)

    Zhang, Liang; Zheng, Fengxia; Qi, Wencai; Wang, Tianqi; Ma, Lingyu; Qiu, Zongbo; Li, Jingyuan

    2016-06-01

    Gamma irradiation at low doses can stimulate the tolerance to environmental stress in plants. However, the knowledge regarding the mechanisms underlying the enhanced tolerance induced by low-dose gamma irradiation is far from fully understood. In this study, to investigate the physiological and molecular mechanisms of heat stress alleviated by low-dose gamma irradiation, the Arabidopsis seeds were exposed to a range of doses before subjected to heat treatment. Our results showed that 50-Gy gamma irradiation maximally promoted seedling growth in response to heat stress. The production rate of superoxide radical and contents of hydrogen peroxide and malondialdehyde in the seedlings irradiated with 50-Gy dose under heat stress were significantly lower than those of controls. The activities of antioxidant enzymes, glutathione (GSH) content and proline level in the gamma-irradiated seedlings were significantly increased compared with the controls. Furthermore, transcriptional expression analysis of selected genes revealed that some components related to heat tolerance were stimulated by low-dose gamma irradiation under heat shock. Our results suggest that low-dose gamma irradiation can modulate the physiological responses as well as gene expression related to heat tolerance, thus alleviating the stress damage in Arabidopsis seedlings.

  4. Effects of /sup 60/Co-. gamma. irradiation on the cell proliferation kinetics of DMBA-induced tongue carcinoma in hamster

    Energy Technology Data Exchange (ETDEWEB)

    Wada, Toshio

    1987-10-01

    In the vocation of the radiation therapy, it is very important to analize the cell kinetics of the normal and tumor tissues, and the radiation effects. Thus, this study analizes the effects of /sup 60/Co-..gamma.. irradiation to DMBA-induced hamster tongue carcinoma (hereafter ''the tumor'') and normal tongue epithelium (hereafter ''the normal'') by using /sup 3/H-TdR puls labeling technics and percentage labeled mitoses (PLM) method. Result : 1) Cell cycle time (Tc) of the Normal was 42.0 hours, and that of the tumor was 18.1 hours. After irradiation, Tc of the tumor was prolonged, but that of the normal was shortened by about 11 hours. 2) Initial labeling index (L.I.) of the tumor was decreased immidiately after irradiation, but on 7 and 10 days L.I. gained back to the pre-irradiation rate. 3) tumor doubling time (Td) was 6.4 +- 1.6 days, and potential doubling time (Tp) was 18.9 hours. 4) Time of pre-DNA synthetic stage (Tg/sub 1/) of the normal was 31.0 hours and that of the tumor was 8.7 hours. After irradiation, Tg/sub 1/ of the normal was shortened by about 10 hours and that of the tumor was prolonged. 5) After irradiation, time of synthetic stage (Ts) of both the normal and the tumor was slightly prolonged. 6) After irradiation, mitotic stage (Tm) of both the normal and the tumor was not changed. 7) Growth fraction (GF) of the normal was 64.5%, and that of the tumor was 79.8%. After irradiation, it was decreased, while it of the tumor was increased temporarily after irradiation. 8) The rate of cell loss facter of the tumor was 0.88.

  5. Effect of gamma-ray irradiation at low doses on the performance of PES ultrafiltration membrane

    Science.gov (United States)

    Zhang, Xue; Niu, Lixia; Li, Fuzhi; Yu, Suping; Zhao, Xuan; Hu, Hongying

    2016-10-01

    The influence of gamma irradiation on the performance of polyether sulfone (PES) ultrafiltration (UF) membrane was investigated at low absorbed doses (0-75 kGy) using a cobalt source. The performance of the UF membranes was tested using low level radioactive wastewater (LLRW) containing three types of surfactants (anionic, cationic and nonionic surfactants). The physical and chemical properties of membrane surface were analyzed, and relationships between these properties and separation performance and fouling characteristics were determined. At 10-75 kGy irradiation, there were no significant changes observed in the membrane surface roughness or polymer functional groups, however the contact angle decreased sharply from 92° to ca. 70° at irradiation levels as low as 10 kGy. When membranes were exposed to the surfactant-containing LLRW, the flux decreased more sharply for higher dosed irradiated membranes, while flux in virgin membranes increased during the filtration processes. The study highlights that fouling properties of membrane may be changed due to the changes of surface hydrophilicity at low dose irradiation, while other surface properties and retentions remain stable. Therefore, a membrane fouling test with real or simulated wastewater is recommended to fully evaluate the membrane irradiation resistance.

  6. Effect of Gamma Rays on Fast Neutron Registration in CR-39

    CERN Document Server

    Kobzev, A P; El-Halem, A A; Abdul-Ghaphar, U S; Salama, T A

    2002-01-01

    A set of CR-39 plastic detectors with front PE radiator was exposed to Am-Be neutron source, which has an emission rate of 0.86\\cdot 10^{7} sec^{-1}, and the neutron dose equivalent rate 1 m apart from the source is equal to 11 mrem/hr. Another set of samples was irradiated by a neutron dose of 4 rem, then exposed to different gamma-ray doses using ^{60}Co source. It was found that the track density grows with the increase of neutron dose and etching time. It was also found that the bulk etching rate V_{B}, the track diameter and the sensitivity of the CR-39 plastic detector with respect to the neutron irradiation increased with increasing gamma-ray dose in the range 1?10 Mrad. These results show that CR-39 can be considered as a promising fast neutron dosimeter and gamma-ray dosimeter.

  7. Reagent-free crosslinking of aqueous gelatin: manufacture and characteristics of gelatin gels irradiated with gamma-ray and electron beam.

    Science.gov (United States)

    Terao, Ken; Nagasawa, Naotsugu; Nishida, Hirokazu; Furusawa, Kazuya; Mori, Yasutaka; Yoshii, Fumio; Dobashi, Toshiaki

    2003-01-01

    In order to obtain a gelatin hydrogel crosslinked by a reagent-free method, gamma-ray and electron beam radiation was applied to porcine, bovine and fish gelatin gels and the products were characterized by measuring the gel fraction, the swelling ratio and the enzymatic degradability. On increasing the radiation dose, the gel fraction increased and both the swelling ratio and the enzymatic degradability decreased. The transition temperature from gel to sol of the hydrogel containing more than 5% mammal gelatins increased up to more than 90 degrees C when gamma-ray or electron beam were irradiated by more than 10 kGy. The results show that the degree of crosslinking of irradiated gelatin hydrogels increases with increasing irradiation dose and with decreasing concentration. It is suggested that the radiation crosslinking occurs around the physical crosslinking point or multiple helix structure of gelatin gel.

  8. Photoluminescence spectra of thin films containing CdSe/ZnS quantum dots irradiated by 532-nm laser radiation and gamma-rays

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Suresh C. [Department of Physics, University of Texas at Arlington, Arlington, TX 76019 (United States)], E-mail: sharma@uta.edu; Murphree, Jay; Chakraborty, Tonmoy [Department of Physics, University of Texas at Arlington, Arlington, TX 76019 (United States)

    2008-11-15

    We have investigated temporal behavior of the photoluminescence (PL) spectra of thin films containing CdSe/ZnS quantum dots irradiated by 532 nm laser radiation and gamma-rays. Under {approx}100 W/cm{sup 2} laser radiation, the PL intensity (I{sub PL}) increases with irradiation time upto about 500 s and thereafter declines linearly. The wavelength of the PL emission ({lambda}{sub peak}) exhibits a blue-shift with exposure time. Upon simultaneous irradiation by 100 W/cm{sup 2} 532-nm laser, as well as 0.57 and 1.06 MeV gamma-rays, the temporal behaviors of both I{sub PL} and {lambda}{sub peak} are significantly different; I{sub PL} increases to a saturation level, and the magnitude of the blue-shift in {lambda}{sub peak} is reduced. We discuss possible mechanisms underlying these results.

  9. Thermal characterization of the HDPE/LDPE blend (10/90) irradiated using gamma-rays

    Energy Technology Data Exchange (ETDEWEB)

    Puig, C.C., E-mail: cpuig@usb.v [Universidad Simon Bolivar, Departamento de Ciencia de los Materiales, Grupo de Polimeros USB, Apdo. 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Albano, C., E-mail: calbano@ivic.v [Instituto Venezolano de Investigaciones Cientificas (IVIC), Centro de Quimica, Laboratorio de Polimeros, Apdo. 21827, Caracas 1020-A (Venezuela, Bolivarian Republic of); Universidad Central de Venezuela, Facultad de Ingenieria, Escuela de Ingenieria Quimica, Laboratorio de Polimeros, Caracas (Venezuela, Bolivarian Republic of); Laredo, E. [Universidad Simon Bolivar, Departamento de Fisica, Grupo de Fisica de Materiales Amorfos y Cristalinos, Apdo. 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Quero, E. [Universidad Simon Bolivar, Departamento de Ciencia de los Materiales, Grupo de Polimeros USB, Apdo. 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Karam, A. [Instituto Venezolano de Investigaciones Cientificas (IVIC), Centro de Quimica, Laboratorio de Polimeros, Apdo. 21827, Caracas 1020-A (Venezuela, Bolivarian Republic of)

    2010-05-01

    Gamma irradiation effect over the properties of slow cooled and fast cooled HDPE/LDPE 10/90 blend was studied. The blend and the neat polyethylenes were irradiated at room temperature in the presence of air using the following doses (4.8 kGy/h): 0, 50, 150, 400 and 1000 kGy. Differential scanning calorimetry (DSC) experiments were carried out using the following heating rates: 5, 10 and 20 deg. C/min. DSC results for the slow and fast cooled blend showed traces with three melting peaks and with increasing irradiation dose two melting peaks were obtained, i.e. the high melting peak shifts toward lower temperatures to merge with the intermediate melting peak into one endotherm. No changes in crystal structure by X-ray diffraction were found as a result of samples irradiation. Radiation crosslinking prevents crystal rearrangements during heating in the DSC. Gel content and melt flow index (MFI) measurements showed that radiation induced a high degree of crosslinking for all samples; gel content values were above 50% and a drop of more than 90% in the MFI was found. Irradiation of slow cooled samples resulted in larger values of gel content and lower MFI values than for fast cooled samples, mainly because of the higher degree of crosslinking for the former.

  10. Effects of gamma-ray irradiation on a cyanate ester/epoxy resin

    Science.gov (United States)

    Idesaki, Akira; Uechi, Hiroki; Hakura, Yoshihiko; Kishi, Hajime

    2014-05-01

    Effects of γ-ray irradiation on a cyanate ester/epoxy resin composed of dicyanate ester of bisphenol A (DCBA) and diglycidyl ether of bisphenol A (DGEBA) were investigated by changes in physicochemical and mechanical properties after the γ-ray irradiation with dose of 100 MGy as maximum at around 40 °C under vacuum. After the irradiation, gases of hydrogen, carbon monoxide and carbon dioxide were evolved, glass transition temperature decreased, and flexural strength also decreased. It was concluded that ether linkages bonded to cyanurate, isocyanurate and oxazolidinone structures are mainly decomposed by the irradiation. After 100 MGy irradiation, the flexural strength of DCBA/DGEBA was maintained more than 170 MPa which is 90% of initial value of 195 MPa. Flexural modulus and density slightly increased to the values of 3.9 GPa and 1.211 g/cm3 from initial values of 3.4 GPa and 1.199 g/cm3, respectively.

  11. Development and characterization of biodegradable polymer blends - PHBV/PCL irradiated with gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Rosario, F. [Faculdade de Tecnologia da Zona Leste (FATEC-ZL), Sao Paulo, SP (Brazil). Centro Paulo Souza; Casarin, S.A.; Agnelli, J.A.M. [Universidade Federal de Sao Carlos (DEMa/UFSCar), SP (Brazil). Dept. de Engenharia de Materiais; Souza Junior, O.F. de [Universidade de Sao Paulo (IFSC/USP), Sao Carlos, SP (Brazil). Inst. de Fisica

    2010-07-01

    This paper presents the results of a study that aimed to develop PHBV biodegradable polymer blends, in a major concentration with PCL, irradiate the pure polymers and blends in two doses of gamma radiation and to analyze the changes in chemical and mechanical properties. The blends used in this study were from natural biodegradable copolymer poly (hydroxybutyrate-valerate) (PHBV) and synthetic biodegradable polymer poly (caprolactone) (PCL 2201) with low molar mass (2,000 g/mol). Several samples were prepared in a co-rotating twin-screw extruder and afterwards, the tensile specimens were injected for the irradiation treatment with 50 kGy to 100 kGy doses and for the mechanical tests. The characterization of the samples before and after the irradiation treatments was performed through scanning electron microscopy (SEM), dynamic mechanical thermal analysis (DMTA), differential scanning calorimetry (DSC) and mechanical tensile tests. (author)

  12. Functionalization and magnetization of carbon nanotubes using Co-60 gamma-ray irradiation

    Science.gov (United States)

    Chen, C. Y.; Fu, M. J.; Tsai, C. Y.; Lin, F. H.; Chen, K. Y.

    2014-10-01

    Functionalized magnetic carbon nanotubes (CNTs) can be used in the biological and biomedical fields as biosensors, drug delivery systems, etc., which makes research into processes for manufacturing modified CNTs quite important. In this paper, Co-60 gamma irradiation is shown to be an effective tool for fabricating functionalized and magnetized CNTs. After the Co-60 gamma irradiation, the presence of carboxylic functional groups on the CNT walls was confirmed by their Fourier transform infrared spectra, and the presence of Fe3O4 was verified by the X-ray diffraction patterns. The functionalized and magnetized CNTs produced using Co-60 gamma irradiation have excellent dispersion properties. The techniques for functionalizing and magnetizing CNTs are introduced in this paper, and applications of the modified CNTs will be reported after more data are gathered.

  13. Simulation and experimental verification of prompt gamma-ray emissions during proton irradiation

    NARCIS (Netherlands)

    Schumann, A.; Petzoldt, J.; Dendooven, P.; Enghardt, W.; Golnik, C.; Hueso-Gonzalez, F.; Kormoll, T.; Pausch, G.; Roemer, K.; Fiedler, F.

    2015-01-01

    Irradiation with protons and light ions offers new possibilities for tumor therapy but has a strong need for novel imaging modalities for treatment verification. The development of new detector systems, which can provide an in vivo range assessment or dosimetry, requires an accurate knowledge of the

  14. {sup 60}Co irradiation effect on color in minimally processed cauliflower (Brassica spp)

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, Thaise C.F.; Rogovschi, Vladimir D.; Santillo, Amanda G.; Villavicencio, Anna L.C.H. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)], e-mail: thaisecfnunes@hotmail.com; Michels, Robert [Hydrofarm Comercio e Representacao de Produtos Agricolas Ltda., Sao Roque, SP (Brazil); Pitombo, Ronaldo N.M. [Universidade de Sao Paulo (USP), SP (Brazil). Faculdade de Ciencias Farmaceuticas. Dept. de Alimentos e Nutricao Experimental

    2009-07-01

    Irradiation is a well-established process with clearly documented safety and efficacy. Consumers require a quality product that is convenient and has fresh-like characteristics and take product appearance, like color, into consideration as a primary criterion; it is considered a key role in food choice, food preference and acceptability. The objective of the present work was to investigate color degradation of cauliflower treated with gamma radiation during 14 days. Cauliflower irradiated samples with 0 and 1.5 kGy showed significant differences for value 'L' on the 10th and 14th day, respectively for value 'b' only the 0 kGy sample showed significant difference on day 10 of storage. On day 10 of shelf-life the irradiated cauliflower with doses of 1 and 1.5 kGy became more yellow compared to the control. The authors concluded that the treatment with low gamma radiation doses keeps the quality of fresh-cut vegetables. (author)

  15. Response of S. boulardii cells to {sup 60} Co irradiation and heat shock

    Energy Technology Data Exchange (ETDEWEB)

    Neves, M.J.; Andrade, A.S.R.; Santos, R.G. [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte, MG (Brazil); Nicoli, J.R. [Minas Gerais Univ., Belo Horizonte, MG (Brazil). Dept. Microbiologia

    1997-12-31

    Full text. Preparation of Saccharomyces boulardii, a non pathogenic yeast, has been widely used in Europe and other countries to prevent gastrointestinal disorders. However the mechanism of action of theses cells on the illness is unknown but the efficacy of S. boulardii depends on its viability. As trehalose is a well known viability protectant in yeast cells against several adverse conditions, we determined its level. We measured the level of trehalose in cells submitted to heat shock, gamma irradiation and simulation of gastric environmental, all these conditions are commonly found during the bio therapeutic production and in the patients oral treatment. Trehalose levels were higher in yeast cells surviving to gamma irradiation ({sup 60} Cobalt) than in control cells. S. boulardii cells growth in log phase and submitted to the heat shock (40 deg C). Accumulated more trehalose than S. cerevisiae and unlikely to these cells, the pool of trehalose accumulated in S. boulardii was mobilized very slowly (70% of the trehalose pool was present 5 hours after the return to the normal temperature 30 deg C). Our results suggested a rather different trehalose metabolism in S. boulardii when compared with S. cerevisiae and showed that one of the response to the stress of irradiation was an increasing on the level of intracellular trehalose

  16. An electron paramagnetic resonance study of PP and PP/SBS blends irradiated with gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Pedro E-mail: silva@ivic.ve; Albano, Carmen; Perera, Rosestela; Gonzalez, Jeanette; Ichazo, Miren

    2004-11-01

    Electron paramagnetic resonance (EPR) measurements of Polypropylene (PP) and its blends with a Styrene-Butadiene-Styrene (SBS) copolymer in 10, 20, 30 and 40 wt.% of SBS were carried out. The samples were irradiated in the 0{<=}D{<=}100 kGy range at a dose rate of 4.8 kGy/h. Typical spectra indicative of the formation of peroxy and alkyl radicals were obtained. The dynamics of formation and recombination of radicals in these samples could be explained using a mixed zero and first order generation-recombination fit of the total spin concentration as a function of the integral dose. The time dependence of the spin concentration was studied assuming a mixed first order fit in the decay process. The parameters obtained from the fitting are interpreted in terms of the rate of formation of free radicals at the irradiation time and in terms of the decay time of the total free radical concentration.

  17. Functionalization and magnetization of carbon nanotubes using Co-60 gamma-ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Chen, C.Y.; Fu, M.J.; Tsai, C.Y. [Division of Isotope Application, Institute of Nuclear Energy Research, Atomic Energy Council, P.O. BOX 3-27 Longtan, Taoyuan County 32546, Taiwan (R.O.C.) (China); Lin, F.H. [Institute of Biomedical Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan (R.O.C.) (China); Chen, K.Y., E-mail: chenky@iner.gov.tw [Division of Isotope Application, Institute of Nuclear Energy Research, Atomic Energy Council, P.O. BOX 3-27 Longtan, Taoyuan County 32546, Taiwan (R.O.C.) (China)

    2014-10-01

    Functionalized magnetic carbon nanotubes (CNTs) can be used in the biological and biomedical fields as biosensors, drug delivery systems, etc., which makes research into processes for manufacturing modified CNTs quite important. In this paper, Co-60 gamma irradiation is shown to be an effective tool for fabricating functionalized and magnetized CNTs. After the Co-60 gamma irradiation, the presence of carboxylic functional groups on the CNT walls was confirmed by their Fourier transform infrared spectra, and the presence of Fe{sub 3}O{sub 4} was verified by the X-ray diffraction patterns. The functionalized and magnetized CNTs produced using Co-60 gamma irradiation have excellent dispersion properties. The techniques for functionalizing and magnetizing CNTs are introduced in this paper, and applications of the modified CNTs will be reported after more data are gathered. - Highlights: Dispersion ability of carbon nanotubes (CNTs) was improved by functionalization. CNTs were easily manipulated by precipitation of magnetic nanoparticles. Our product can be used as versatile biosensor substrate for biomarker screening.

  18. Induction of skin papillomas in the rabbit, Oryctologus cuniculus, by bites of a blood-sucking insect, Cimex lectularius, irradiated by gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    el-Mofty, M.M.; Sakr, S.A.; Younis, M.W. (Alexandria Univ. (Egypt))

    1989-11-01

    Bed bugs, Cimex lectularius, irradiated with gamma rays were allowed to suck blood from shaved areas of the skin of rabbits, Oryctolagus cuniculus, 2 times/week for 5 months and then once weekly for another 5 months. This significantly induced the formation of skin papillomas and sweat gland hyperplasia in five out of nine experimental animals. It is speculated that the saliva of the irradiated bugs was activated by gamma rays and was responsible for the induction of skin papillomas. Because bed bugs play a significant role in the transmission of virus, it is also speculated that there is a virus in the saliva of bugs; this virus may be activated by gamma radiation and causes the development of papillomas in the skin.

  19. Simulation and experimental verification of prompt gamma-ray emissions during proton irradiation

    Science.gov (United States)

    Schumann, A.; Petzoldt, J.; Dendooven, P.; Enghardt, W.; Golnik, C.; Hueso-González, F.; Kormoll, T.; Pausch, G.; Roemer, K.; Fiedler, F.

    2015-05-01

    Irradiation with protons and light ions offers new possibilities for tumor therapy but has a strong need for novel imaging modalities for treatment verification. The development of new detector systems, which can provide an in vivo range assessment or dosimetry, requires an accurate knowledge of the secondary radiation field and reliable Monte Carlo simulations. This paper presents multiple measurements to characterize the prompt γ-ray emissions during proton irradiation and benchmarks the latest Geant4 code against the experimental findings. Within the scope of this work, the total photon yield for different target materials, the energy spectra as well as the γ-ray depth profile were assessed. Experiments were performed at the superconducting AGOR cyclotron at KVI-CART, University of Groningen. Properties of the γ-ray emissions were experimentally determined. The prompt γ-ray emissions were measured utilizing a conventional HPGe detector system (Clover) and quantitatively compared to simulations. With the selected physics list QGSP_BIC_HP, Geant4 strongly overestimates the photon yield in most cases, sometimes up to 50%. The shape of the spectrum and qualitative occurrence of discrete γ lines is reproduced accurately. A sliced phantom was designed to determine the depth profile of the photons. The position of the distal fall-off in the simulations agrees with the measurements, albeit the peak height is also overestimated. Hence, Geant4 simulations of prompt γ-ray emissions from irradiation with protons are currently far less reliable as compared to simulations of the electromagnetic processes. Deviations from experimental findings were observed and quantified. Although there has been a constant improvement of Geant4 in the hadronic sector, there is still a gap to close.

  20. Simulation and experimental verification of prompt gamma-ray emissions during proton irradiation.

    Science.gov (United States)

    Schumann, A; Petzoldt, J; Dendooven, P; Enghardt, W; Golnik, C; Hueso-González, F; Kormoll, T; Pausch, G; Roemer, K; Fiedler, F

    2015-05-21

    Irradiation with protons and light ions offers new possibilities for tumor therapy but has a strong need for novel imaging modalities for treatment verification. The development of new detector systems, which can provide an in vivo range assessment or dosimetry, requires an accurate knowledge of the secondary radiation field and reliable Monte Carlo simulations. This paper presents multiple measurements to characterize the prompt γ-ray emissions during proton irradiation and benchmarks the latest Geant4 code against the experimental findings. Within the scope of this work, the total photon yield for different target materials, the energy spectra as well as the γ-ray depth profile were assessed. Experiments were performed at the superconducting AGOR cyclotron at KVI-CART, University of Groningen. Properties of the γ-ray emissions were experimentally determined. The prompt γ-ray emissions were measured utilizing a conventional HPGe detector system (Clover) and quantitatively compared to simulations. With the selected physics list QGSP_BIC_HP, Geant4 strongly overestimates the photon yield in most cases, sometimes up to 50%. The shape of the spectrum and qualitative occurrence of discrete γ lines is reproduced accurately. A sliced phantom was designed to determine the depth profile of the photons. The position of the distal fall-off in the simulations agrees with the measurements, albeit the peak height is also overestimated. Hence, Geant4 simulations of prompt γ-ray emissions from irradiation with protons are currently far less reliable as compared to simulations of the electromagnetic processes. Deviations from experimental findings were observed and quantified. Although there has been a constant improvement of Geant4 in the hadronic sector, there is still a gap to close.

  1. DC Characteristics of Gamma-ray Irradiated SiGe HBT in Comparison with Si BJT

    Institute of Scientific and Technical Information of China (English)

    MENG Xiang-ti; HUANG Qian; WANG Ji-lin; CHEN Pei-yi; TSIEN Pei-hsin

    2006-01-01

    The changes of DC characteristics of SiGe HBT after being submitted to γ-ray irradiation of 700 krad, 7 000 krad and 10 000 krad were compared to those of Si BJT. Generally speaking, Ib and Ib - Ib0 increase with the doses increasing. For SiGe HBT, with the doses increasing, Ic and Ic - Ic0 as well as the related changes of the current gain (β) will decrease at higher Vbe, while for Si BJT, with the doses increasing, after irradiation, Ib and Ic - Ic0 increase; β and its related changes also decrease with their differences, however, tending to be very small at high doses of 7 000 krad and 10 000 krad. Moreover, given the same doses, the decreases of β are much larger than SiGe HBT, which shows that SiGe HBT's anti-radiation performance proves to be better than Si BJT. Still, in SiGe HBT, some strange phenomena were observed: Ic - Ic0 will increase after the radiation of 7 000 krad in less than 0.65 V and as will β in less than 0.75 V. The mechanism of radiation-induced change in DC characteristics was also discussed.

  2. On-site gamma-ray spectroscopic measurements of fission gas release in irradiated nuclear fuel.

    Science.gov (United States)

    Matsson, I; Grapengiesser, B; Andersson, B

    2007-01-01

    An experimental, non-destructive in-pool, method for measuring fission gas release (FGR) in irradiated nuclear fuel has been developed. Using the method, a significant number of experiments have been performed in-pool at several nuclear power plants of the BWR type. The method utilises the 514 keV gamma-radiation from the gaseous fission product (85)Kr captured in the fuel rod plenum volume. A submergible measuring device (LOKET) consisting of an HPGe-detector and a collimator system was utilised allowing for single rod measurements on virtually all types of BWR fuel. A FGR database covering a wide range of burn-ups (up to average rod burn-up well above 60 MWd/kgU), irradiation history, fuel rod position in cross section and fuel designs has been compiled and used for computer code benchmarking, fuel performance analysis and feedback to reactor operators. Measurements clearly indicate the low FGR in more modern fuel designs in comparison to older fuel types.

  3. ESR investigations on {gamma}-ray irradiated 3-methyl nylon 3

    Energy Technology Data Exchange (ETDEWEB)

    Catiker, Efkan [Abant Izzet Baysal University, Department of Chemistry, 14280 Bolu (Turkey); Guven, Olgun [Hacettepe University, Department of Chemistry, 06532 Ankara (Turkey); Ozarslan, Ozdemir [Abant Izzet Baysal University, Department of Chemistry, 14280 Bolu (Turkey); Chipara, Mircea [University of Texas Pan American, Department of Physics and Geology, 1201 W. University Drive, Edinburg, TX 78541-2999 (United States)], E-mail: mchipara@utpa.edu

    2008-06-15

    Electron spin resonance spectroscopy investigations on {gamma} irradiated 3-methyl nylon 3 (poly-3-methyl {beta}-alanine) are reported. The resonance spectra (recorded after the irradiation in nitrogen atmosphere has been stopped) have been attributed to the parallel and perpendicular components of a triplet line assigned to the delocalization of the uncoupled electron over an effective nuclear spin 1. It was suggested that this effective spin arises from the fast tunneling/rotation of a proton between two positions. The resonance spectra have been simulated with accuracy by using a simplified spin Hamiltonian and assuming Lorentzian-like resonance line shapes and axial asymmetry of the resonance line due to the trapping of free radicals in randomly oriented crystallites. The time evolution of free radicals in nitrogen atmosphere at room temperature has been analyzed. The decay kinetics of stable free radicals in 3-methyl nylon 3 (under inert atmosphere) has been investigated. It was shown that the radiation-induced radicals in inert atmosphere decay through a unimolecular reaction.

  4. Trace the polymerization induced by gamma-ray irradiated silica particles

    Science.gov (United States)

    Lee, Hoik; Ryu, Jungju; Kim, Myungwoong; Im, Seung Soon; Kim, Ick Soo; Sohn, Daewon

    2016-08-01

    A γ-ray irradiation to inorganic particles is a promising technique for preparation of organic/inorganic composites as it offers a number of advantages such as an additive-free polymerizations conducted under mild conditions, avoiding undesired damage to organic components in the composites. Herein, we demonstrated a step-wise formation mechanism of organic/inorganic nanocomposite hydrogel in detail. The γ-ray irradiation to silica particles dispersed in water generates peroxide groups on their surface, enabling surface-initiated polymerization of acrylic acid from the inorganic material. As a result, poly(acrylic acid) (PAA) covers the silica particles in the form of a core-shell at the initial stage. Then, PAA-coated silica particles associate with each other by combination of radicals at the end of chains on different particles, leading to micro-gel domains. Finally, the micro-gels are further associated with each other to form a 3D network structure. We investigated this mechanism using dynamic light scattering (DLS) and transmission electron microscopy (TEM). Our result strongly suggests that controlling reaction time is critical to achieve specific and desirable organic/inorganic nanocomposite structure among core-shell particles, micro-gels and 3D network bulk hydrogel.

  5. Effect of 60Co gamma irradiation on dielectric and complex impedance properties of Dy3+ substituted Ni-Zn nanoferrites

    Science.gov (United States)

    Veena, M.; Somashekarappa, A.; Shankaramurthy, G. J.; Jayanna, H. S.; Somashekarappa, H. M.

    2016-12-01

    Nanocrystalline Ni1-xZnxFe2-yDyyO4 (x=0.0, 0.2, 0.4, 0.6, 0.8, 1.0; y=0.0 and 0.1) ferrites were synthesized by combustion method. Ni-Zn-Dy nanoferrites were investigated by X-ray diffraction, scanning electron microscopy, dielectric and impedance properties, before and after γ-irradiation process by 60Co γ-radiation with a dose rate of 310 kGy. The lattice parameter of irradiated samples increased attributed to the conversion of smaller size Fe3+ ions to larger size Fe2+ ions on ionizing effect of gamma radiation. Experimental results reveal that reduction in dielectric constant (ε‧), loss tangent (tan δ), real (Z‧) and imaginary (Z‧‧) impedance and increase in ac conductivity (σac) have been increased with increasing in frequency. It was found that ε‧, tan δ, σac increase, Z‧‧ and Z‧‧ reach a maximum value and thereafter decrease with further Zn ion substitution. The values of ε‧, tan δ and σac decrease with Dy3+ substitution and enhanced after irradiation. The complex impedance analysis suggesting predominant contribution to conduction was through the grain boundary.

  6. Paramecium tetraurelia growth stimulation under low-level chronic irradiation: investigations on a possible mechanism. [/sup 60/Co

    Energy Technology Data Exchange (ETDEWEB)

    Croute, F.; Soleilhavoup, J.P.; Vidal, S.; Dupouy, D.; Planel, H.

    1982-12-01

    Experiments were carried out to demonstrate the effects of low-level chronic irradiation on Paramecium tetraurelia proliferation. Biological effects were strongly dependent on the bacterial density of culture medium and more exactly on the catalase content of the medium. Significant growth stimulation was found under /sup 60/Co chronic irradiation at a dose rate of 2 rad/year when paramecia were grown in a medium containing a high bacterial concentration (2.5 x 10/sup 2/ cells/m) or supplemented with catalase (300 U/ml). In a medium with a low bacterial density (1 x 10/sup 6/ cell/ml) or supplemented with a catalase activity inhibitor, growth simulation was preceded by a transitory inhibiting effect which could be correlated with extracellularly radioproduced H/sub 2/O/sub 2/. H/sub 2/O/sub 2/ addition appeared to be able to simulate the biological effects of chronic irradiation. A possible mechanism is discussed.We proposed that the stimulating effects were the result of intracellular enzymatic scavenging of radioproduced H/sub 2/O/sub 2/.

  7. Immune response against the irradiated Bothropstoxin-1 with {sup 60}Co: identification of main cytokines involved and the participation of scavengers substances; Resposta imune frente a Bothropstoxina-1 irradiada com {sup 60}Co: identificacao das principais citocinas envolvidas e a participacao de substancias scavengers

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Janaina Baptista

    2009-07-01

    Considering the effects of gamma radiation on proteins and the ability of immune system to recognize modified macromolecules, we have identified the major cytokines involved in immune response of B10.PL, BALB/c and Knockout- IFN{gamma} mice exposed to native or irradiated bothropstoxin-1 (BTHX-1), in the presence and absence of scavengers substances. In order to evaluate possible molecule structural modifications after being irradiated ({sup 60}Co gamma rays), bothropstoxin-1 was submitted to SDS-PAGE analyses. Our results indicated that irradiation process has promoted modifications in the BTHX-1 molecule, however, in the presence of scavengers and even after irradiation process, the main band of toxin was preserved (14 kDa). Sera of animals immunized with the native or irradiated toxin, in the presence or not of scavengers, were analyzed in order to quantify specific isotopes. While the native BTHX-1 induced a predominant Th2 response, the irradiated toxin apparently promoted a switch towards a Th1 pattern. The toxin, when irradiated in the presence of t-butanol, induced to a lower production of IgG2b (Th1 response) if compared with the irradiated toxin without scavengers. We also performed a Real-time PCR to quantify the expression of cytokines IFN-{gamma}, IL-2, IL-4 and IL-10 in spleen cells from mice. The cells of B10.PL and BALB/c mice immunized with native BTHX-1 and in vitro stimulated with irradiated toxin, showed higher expression of IFN-{gamma} and IL-2 (Th1 response) than the control sample. The cells of Knockout-IFN{gamma} mice immunized with native BTHX-1 showed higher expression of IL-4 (Th2 response). The cells obtained of B10.PL and BALB/c mice immunized with BTHX-1 + t-butanol, showed higher expression of IL-4 and IL-10, respectively. These facts reinforce the involvement of OH in the modulation of immune response against the irradiated toxin. (author)

  8. Preparation of hydrogels for atopic dermatitis containing natural herbal extracts by gamma-ray irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Youn-Mook; An, Sung-Jun; Kim, Hae-Kyoung [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong Jeongeup-si Jellabuk-do, 580-185 (Korea, Republic of); Kim, Yun-Hye [AMOTECH Co., Ltd., Kimpo-City, Kyungki-do (Korea, Republic of); Youn, Min-Ho; Gwon, Hui-Jeong; Shin, Junhwa [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong Jeongeup-si Jellabuk-do, 580-185 (Korea, Republic of); Nho, Young-Chang [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong Jeongeup-si Jellabuk-do, 580-185 (Korea, Republic of)], E-mail: ycnho@kaeri.re.kr

    2009-07-15

    Atopic dermatitis (AD) is a familial and chronic inflammatory pruritic skin disease that affects a large number of children and adults in industrialized countries. It is known that one of the prominent features of AD and chronic pruritus is partially due to the histamine released from mast cell. In this work, hydrogel patches with natural herbal extracts were prepared by 'freezing and thawing', and a gamma irradiation. It showed eminent healing results as a consequence of long-term moisturizing effects and natural herbal extracts on atopic wounds. Besides its non-toxicity and human harmlessness, it can be easily attached to or detached from the skin without any trace and help patients to feel refreshment when attached. Based on this work, the hydrogel patches we made can be potentially used as an alternative remedy for not only pruritus in AD, but other dermatitis.

  9. Low Dose Gamma Irradiation Potentiates Secondary Exposure to Gamma Rays or Protons in Thyroid Tissue Analogs

    Energy Technology Data Exchange (ETDEWEB)

    Green, Lora M

    2006-05-25

    We have utilized our unique bioreactor model to produce three-dimensional thyroid tissue analogs that we believe better represent the effects of radiation in vivo than two-dimensional cultures. Our thyroid model has been characterized at multiple levels, including: cell-cell exchanges (bystander), signal transduction, functional changes and modulation of gene expression. We have significant preliminary data on structural, functional, signal transduction and gene expression responses from acute exposures at high doses (50-1000 rads) of gamma, protons and iron (Green et al., 2001a; 2001b; 2002a; 2002b; 2005). More recently, we used our DOE funding (ending Feb 06) to characterize the pattern of radiation modulated gene expression in rat thyroid tissue analogs using low-dose/low-dose rate radiation, plus/minus acute challenge exposures. Findings from these studies show that the low-dose/low-dose rate “priming” exposures to radiation invoked changes in gene expression profiles that varied with dose and time. The thyrocytes transitioned to a “primed” state, so that when the tissue analogs were challenged with an acute exposure to radiation they had a muted response (or an increased resistance) to cytopathological changes relative to “un-primed” cells. We measured dramatic differences in the primed tissue analogs, showing that our original hypothesis was correct: that low dose gamma irradiation will potentiate the repair/adaptation response to a secondary exposure. Implications from these findings are that risk assessments based on classical in vitro tissue culture assays will overestimate risk, and that low dose rate priming results in a reduced response in gene expression to a secondary challenge exposure, which implies that a priming dose provides enhanced protection to thyroid cells grown as tissue analogs. If we can determine that the effects of radiation on our tissue analogs more closely resemble the effects of radiation in vivo, then we can better

  10. The Irradiation Characteristics of the Kur Heavy Water Facility (ii) - Neutron and Gamma-Ray Dose Measurements with a Twin-Chamber

    Science.gov (United States)

    Sakurai, Yoshinori; Kobayashi, Tooru

    2003-06-01

    The Heavy Water Neutron Irradiation Facility of the Kyoto University Reactor can supply neutron energy spectra from almost pure thermal to mainly epi-thermal, using a spectrum shifter and thermal neutron filters. We will report about the measurement of the neutron and gamma-ray doses using a twin-chamber. The used twin-chamber is the combination of a tissue-equivalent ionization-chamber and a graphite ionization chamber, with detecting volumes of 80 cc. From the comparisons between the chamber-measured dose rates and the nominal values, it was confirmed that the relative dependencies of the neutron and gamma-ray doses on the heavy water thickness, were almost the same, excepting the smaller heavy-water-thickness mode, such as CB-0000-F.

  11. 60Coγ射线损伤后小鼠造血系统生理指标的动态变化%Changes of Physiological Indexes in Hematopoietic System of Mice after 60Coγ Ray Irradiation

    Institute of Scientific and Technical Information of China (English)

    侯新然; 王晓波; 袭荣刚; 李忠亮; 高慧媛; 吴立军; 马晓梅

    2012-01-01

    Objective To explore the physiological variation of the hematopoietic system in mice after C07 ray irradiation. Methods Body weight, peripheral blood cell counts,the immune organ index and pathological changes in femoral bone marrow of mice were measured at different times after whole-body irradiation with C07 ray. The doses were 2,4,6 Gy respectively. Results The changes of peripheral blood of mice were different. The white blood cell counts declined most rapidly and obviously,followed by the platelet count,with a dose-effect relationship. Three days after radiation, the immune organ index of mice decreased significantly compared with the immune organ index in mice unirradiated. Myeloid elements in bone marrow were reduced and bone marrow hematopoiesis was depressed. Body weight of irradiated mice grew slowly, without significant difference with mice unirradiated. Conclusion 60Coγ ray radiation can decrease peripheral blood cells, decrease the immune organ index and inhibit bone marrow cell proliferation in mice.%目的 探索小鼠60Coγ射线损伤后造血系统各项生理指标的变化规律.方法 采用60Coγ射线对小鼠进行一次性全身照射,剂量分别为2、4、6 Gy,在不同时间分别测定小鼠体质量,外周血细胞计数,免疫器官指数及股骨骨髓的病理变化.结果 照射后小鼠的外周血象有变化,其中白细胞下降最迅速且明显,其次是血小板,且具有剂量效应关系.照射后3d免疫器官指数下降明显,与对照组比较具有显著性差异;骨髓造血细胞数目迅速减少,出现造血抑制;照射后小鼠体质量增加缓慢,但与对照组比较无显著性差异.结论 60Coγ射线照射可引起小鼠外周血细胞下降,免疫器官指数下降,并抑制骨髓造血细胞增生.

  12. High gamma-rays irradiation tests of critical components for ITER (International Thermonuclear Experimental Reactor) in-vessel remote handling system

    Energy Technology Data Exchange (ETDEWEB)

    Obara, Kenjiro; Kakudate, Satoshi; Oka, Kiyoshi [Department of Fusion Engineering Research, Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Naka, Ibaraki (Japan)] [and others

    1999-02-01

    In ITER, the in-vessel remote handling is inevitably required to assemble and maintain the activated in-vessel components due to deuterium and tritium operation. Since the in-vessel remote handling system has to be operated under the intense of gamma ray irradiation, the components of the remote handling system are required to have radiation hardness so as to allow maintenance operation for a sufficient length of time under the ITER in-vessel environments. For this, the Japan, European and Russian Home Teams have extensively conducted gamma ray irradiation tests and quality improvements including optimization of material composition through ITER R and D program in order to develop radiation hard components which satisfy the doses from 10 MGy to 100 MGy at a dose rate of 1 x 10{sup 6} R/h (ITER R and D Task: T252). This report describes the latest status of radiation hard component development which has been conducted by the Japan Home Team in the ITER R and D program. The number of remote handling components tested is about seventy and these are categorized into robotics (Subtask 1), viewing system (Subtask 2) and common components (Subtask 3). The irradiation tests, including commercial base products for screening, modified products and newly developed products to improve the radiation hardness, were carried out using the gamma ray irradiation cells in Takasaki Establishment, JAERI. As a result, the development of the radiation hard components which can be tolerable for high temperature and gamma radiation has been well progressed, and many components, such as AC servo motor with ceramics insulated wire, optical periscope and CCD camera, have been newly developed. (author)

  13. Evaluation by EPR of potential antioxidant components of {sup 60}Co-irradiated varieties of soybean; Avaliacao por RPE de componentes com potencial antioxidante de variedades de soja irradiadas com {sup 60}CO

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Marcos Ronaldo Ramos de

    2009-07-01

    Brazil is today the second main producer of soybean in the world with a planted ground of about 21 million hectares and an annual production of 60 million tons in 2008, being slight more than a fourth of the annual production. The presence of flavonoids, particularly isoflavones in soybean products has been related as important for human health. It has been suggested that flavonoids play a role in the protection of plants by screening vital cellular components from damaging UV radiation. Electron paramagnetic resonance (EPR) spectroscopy can measure free radicals produced by dissociation molecules resulting from irradiation. It has been successfully employed for the detection of some irradiated food products. Twenty one Brazilian soybean cultivars from two crops were gamma-irradiated with a {sup 60}Co source and evaluated by EPR. Correlation coefficients were made among the central EPR signal (g = 2.0039) and the total and partial isoflavones contents. There was no correlation with total contents, though glicitein and acetyl-daidzin showed a negative correlation. Even 7 months after irradiation the intensity of central EPR signal were high enough to distinguish the irradiated samples. EPR measurements of separated parts of the grain were more efficient for that purpose, particularly from hilum and coat. The radiation did not change substantially the total isoflavone contents, although there were some evidences suggesting some conversion of glycosides to aglycones. (author)

  14. The effects of gamma-ray irradiation to strawberry (Fragaria x ananassa Duch.) calli on shoot regeneration, achene formation and morphological variations of regenerants

    Energy Technology Data Exchange (ETDEWEB)

    Kasumi, Masakazu [Plant Biotechnology Inst., Ibaraki Agricultural Center, Iwama, Ibaraki (Japan)

    2002-05-01

    Strawberry (Fragaria x ananassa 'Nyoho') calli, derived from anthers, were irradiated with gamma -ray at dosages from 100 to 1,600 Gy (10 Gy {center_dot} hr{sup -}1) and their effects on callus growth, plant regeneration, and somaclonal variation were analyzed. The growth of callus and percentage of plant regeneration from the callus were reduced slightly at dosages less than 200 Gy, moderately at 400 Gy, and markedly above 800 Gy. Fruit growth associated with seed fertility (>50 % ) was morphologically normal at less than 100 Gy, whereas achene formation was significantly inhibited above 200 Gy. The percentages of morphological variation in regenerants formed from the irradiated callus were:13.7 (no irradiation), 18.6 (100 Gy), 66.0 (200 Gy), 75.7 (400 Gy), and 97.0 (800 Gy). Furthermore, higher dosages yielded wider variations, e.g., thick and small leaf, light leaf color, white flesh, and long fruit. In some regenerants, more than one morphological aberrations developed, some of which were transmissible to daughter plants. These results revealed that the irradiating strawberry callus with gamma - ray resulted in a higher degree and wider spectrum of somaclonal variation than did simple callus culture. (author)

  15. Obtainment of a drug delivery system from PVAL irradiated by gamma rays; Obtencao de um sistema de liberacao controlada de drogas a partir do PVAL irradiado com radiacao gama

    Energy Technology Data Exchange (ETDEWEB)

    Terence, Mauro Cesar

    2002-07-01

    The poly(vinyl alcohol) (PVAL) is a polymer used as biomaterial. In this work the PVAL was irradiated by gamma rays from {sup 60}Co source with doses up to 200 kGy. The PVAL was used to prepare hydrogels that may be used as a drug delivery system in ocular implant, for pair PVAL/dihidroxypropoximethyl guanine, where the last one is used for treatment of people with retinite caused by cytomegalovirus. The dose effect was studied on various properties of PVAL: the molecular weight by viscosity, the crosslink degree (G{sub cross}-l{sub ink}= 8,5) calculated from gel dose (Dg = 7,8 kGy), the average molecular weight between crosslinks, crosslinking density, tensile strength at break and the degree of crystallinity by differential scanning calorimetry. Formation and thermal decay radical were studied by electronic paramagnetic resonance. It was used the technique of superposition and subtraction of spectra obtained at various temperatures (77 K, 125 K, 170 K, 230 K and 280 K). The radicals formed were identified on irradiated PVAL on vacuum and air at 77K with 20 kGy. The thermal decay showed that air caused polymer oxidation, even after end the irradiation, because the {center_dot}OH, RO{center_dot} and ROO {center_dot} radicals were formed. The dose effect on molecular structure of PVAL was studied by transmission spectroscopy on infrared region and nuclear magnetic resonance of proton. The PVAL structural alteration was not observed up to 200kGy, although crosslink occurred on PVAL. The PVAL hydrogel formation occurred at doses upper 70 kGy and drug controlled released occurred with zero order kinetic on PVAL hydrogel irradiated with 80 kGy. (author)

  16. RBE values and repair characteristics for colo-rectal injury after caesium 137 gamma-ray and neutron irradiation. II. Fractionation up to ten doses.

    Science.gov (United States)

    Terry, N H; Denekamp, J

    1984-07-01

    Early and late colo-rectal damage in mice have been assessed after 137Cs gamma irradiation and 3 MeV neutrons given as 1,2,5 or 10 fractions. Damage was measured by early changes in body weight, the late production of short faecal pellets and the pattern of lethality after irradiation. The data have been analysed in terms of the time course of expression of damage, fractionation effects and the RBE for neutrons over a wide range of doses per fraction (0.5-12.5 Gy neutrons, 3.5-33.5 Gy gamma rays). An initial epithelial denudation led to an early loss of weight, maximal at 11-17 days after irradiation. A dose-dependent weight reduction persisted over the animals' life-time. Deaths after localised pelvic gamma irradiation were progressive with no sharp demarcation between early or late phases of injury. The time course for lethality was qualitatively similar after neutrons. Beyond six months the rectum became constricted by fibrosis and a higher proportion of small faecal pellets was observed. At 6-15 months relatively shallow dose-response curves were obtained for this change. The sparing effect of fractionation was marked for the gamma-irradiated mice and almost absent after neutrons. A very high repair increment (11 Gy) was seen with two gamma-ray fractions of 20 Gy. At lower doses per fraction the proportion of each gamma-ray fraction recovered was 50-69% for all assays, i.e., similar to that for other normal tissues. There was a slight enhancement in the sparing effect for the late compared with the early assays over the lower dose range. The RBE was strongly dependent on dose per fraction because of the lack of reparable damage after neutrons. The RBE for both early and late effects was 5.0 at a neutron dose per fraction of 1 Gy. Extrapolation of the RBE data to lower doses, using the linear quadratic model, predicts a higher RBE for late (7.4-12.7) than for early damage (5.7-8.5) if gamma-ray doses below 5 Gy are used.

  17. Biochemical and pharmacological studies of native and irradiated crotamine with gamma radiation of {sup 60}Co; Estudo bioquimico e farmacologico das crotaminas nativa e irradiada com radiacao gama de {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Mitake, Malvina Boni

    2000-07-01

    Ionizing radiation can change the molecular structure and affect the biological properties of biomolecules. This has been employed to attenuate animal toxins. Crotamine is a strongly basic polypeptide from the South American rattlesnake venom, composed of 42 amino acid residues. It induces skeletal muscle spasms leading to a spastic paralysis of hind limbs in mice. The objective of this thesis was carry out biochemical and pharmacological studies of native and irradiated crotamine with {sup 60} Co. Crotamine was purified from Crotalus durissus terrificus venom by Sephadex G-100 gel filtration followed by ion exchange chromatography, using a Fast Performance Liquid Chromatography (FPLC) system. It was irradiated at 2 mg/ml in 0.15 M Na Cl with 2.0 kGy gamma radiation emitted by a {sup 60} Co source. The native and irradiated crotamine were evaluated by biochemical characterization, toxic activity (LD{sub 50} and biodistribution. The native and irradiated crotamine were labelled with 29.6 MBq of {sup 125} I using chloramine T method, and separated in a Sephadex G-50 column. Male Swiss mice (35{+-} 5 g), were injected i.p. with o.1 mL (2.4 x 10{sup 6} cpm/mouse) of {sup 125} I native crotamine or with 0.4 mL (1.3 x 10{sup 6} cpm/mouse) of {sup 125} I irradiated crotamine. At 0.08; 0.25; 0.5; 1; 2; 4; 8; 12 and 24 hours the animal were killed by ether inhalation. Blood, spleen, liver, kidneys, brain, lungs, heart, and skeletal muscle were collected in order to determine radioactivity content. The results showed that gamma radiation did not change the protein concentration, the electroforetic profile or the primary structure of the protein, although differences were shown by spectroscopic techniques. The gamma radiation diminished the toxicity of crotamine, but it did not abolish bioactivity. Biodistribution studies showed that native and irradiated crotamine have hepatic metabolism and renal elimination. The native and irradiated crotamine have affinity by skeletal

  18. Gamma-ray irradiation induced bulk photochromism in WO{sub 3}–P{sub 2}O{sub 5} glass

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Wei [Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237 (China); Baccaro, Stefania; Cemmi, Alessia [ENEA UTTMAT-IRR, Via Anguillarese 301, 00123 Rome (Italy); Xu, Xiaoqing [Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237 (China); ENEA UTTMAT-IRR, Via Anguillarese 301, 00123 Rome (Italy); Chen, Guorong, E-mail: grchen@ecust.edu.cn [Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237 (China)

    2015-11-01

    In the present work, photochromism of WO{sub 3}–P{sub 2}O{sub 5} glass under gamma-ray irradiation was reported. As-prepared glass samples with different WO{sub 3} content are all optically transparent in the visible wavelength range thanks to the addition of a small amount of oxidizing couple Sb{sub 2}O{sub 3}–NaNO{sub 3}. The photochromic properties are identified by transmission spectra of the glasses before and after irradiation. The results show that the irradiation induced darkening results from the reduction of W{sup 6+} to W{sup 5+} or W{sup 4+}. The existence of WO{sub 6} clusters in glasses of high WO{sub 3} content is proved by XPS, which is the main reason for the obvious photochromic effects. The WO{sub 3}–P{sub 2}O{sub 5} glass is a promising candidate in gamma-ray sensitive detector.

  19. Thermoluminescence properties of Al{sub 2}O{sub 3}:Tb nanoparticles irradiated by gamma rays and 85 MeV C{sup 6+} ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Salah, Numan, E-mail: nsalah@kau.edu.sa [Center of Nanotechnology, King Abdulaziz University, Jeddah 21589 (Saudi Arabia); Alharbi, Najlaa D. [Sciences Faculty for Girls, King Abdulaziz University, Jeddah 21589 (Saudi Arabia); Habib, Sami S. [Center of Nanotechnology, King Abdulaziz University, Jeddah 21589 (Saudi Arabia); Lochab, S.P. [Inter-University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India)

    2015-11-15

    Carbon ions beam is recently recognized as an ideal cancer treatment modality, because of its excellent local tumor control. These ions have a high relative biological effectiveness resulting from high linear energy transfer (LET) and their sharp Bragg peak. However, the dose of those energetic ions needs to be measured with great precision using a proper dosimeter. Aluminum Oxide (Al{sub 2}O{sub 3}) is a highly luminescent phosphor widely used for radiation dosimetry using thermoluminesence (TL) technique. In this work nanoparticles of this material activated by different elements like Eu, Tb, Dy, Cu and Ag were evaluated for their TL response to gamma rays irradiation. Tb doped sample is found to be the most sensitive sample, which could be selected for exposure to 85 MeV C{sup 6+} ion beam in the fluence range 10{sup 9}–10{sup 13} ions/cm{sup 2}. The obtained result shows that C ion beam irradiated sample has a simple glow curve structure with a prominent glow peak at around 230 °C. This glow curve has a dosimetric peak better than those induced by gamma rays. This glow peak exhibits a linear response in the range 10{sup 9}–10{sup 11} ions/cm{sup 2}, corresponding to the equivalent absorbed doses 0.285–28.5 kGy. The absorbed doses, penetration depths and main energy loss were calculated using TRIM code based on the Monte Carlo simulation. The wide linear response of Al{sub 2}O{sub 3}:Tb nanoparticles along with the low fading makes this low cost nanomaterial a good candidate for C ion beam dosimetry. - Highlights: • Nanoparticles of Al{sub 2}O{sub 3} doped with Eu, Tb, Dy, Cu and Ag were synthesised. • They were evaluated for their TL response to gamma rays and C ion beam irradiation. • Tb doped sample is the most sensitive sample to gamma rays. • Al{sub 2}O{sub 3}:Tb was exposed to 85 MeV C{sup 6+} ion beam in the fluence range 10{sup 9}-10{sup 13} ions/cm{sup 2}. • The glow peak induced by C ions has a linear response in the range 10{sup 9

  20. Numerical simulation of 60Co-gamma irradiation effects on electrical characteristics of n-type FZ silicon X-ray detectors

    Science.gov (United States)

    Vigneshwara Raja, P.; Rao, C. V. S.; Narasimha Murty, N. V. L.

    2016-07-01

    This paper describes the gamma irradiation effects on the electrical characteristics of n-type float zone (FZ) silicon detectors by incorporating a 4-level 60Co-gamma radiation damage model in the commercial device simulator for plasma X-ray tomography diagnostics. In the simulations, a segmented n-type silicon detector (i.e. p+-n-n+ structure) is considered with varying substrate resistivity (ρ = 5.4, 2.5, and 0.3 kΩ cm). The simulation results have been validated with the reported experimental measurements carried out on similar device structures. The 60Co-gamma irradiation induced changes in the electrical characteristics of the detectors are analyzed up to the dose of 3500 Mrad. The possible gamma induced degradation in the X-ray response of the detectors is investigated from the changes in the effective doping concentration and the leakage current of the detectors. The survival of the gamma irradiated detectors is predicted from the simulation studies. The comparison between the 60Co-gamma and 14.1 MeV neutron irradiation effects (typical fusion environments) on silicon detectors is attempted.

  1. Transfection of p27 kip1 enhances radiosensitivity induced by 60Coγ-irradiation in hepatocellular carcinoma HepG2 cell line

    Institute of Scientific and Technical Information of China (English)

    Xiao-Xiang Guan; Long-Bang Chen; Gui-Xia Ding; Wei De; Ai-Hua Zhang

    2004-01-01

    AIM: To study the cell cycle alterations of human hepatoma cell line HepG2 in vitro after 60Co γ-irradiation and further to examine the mechanisms underlying the enhancement of radiosensitivity to γ-irradiation in HepG2 transiently transfected with wild type p27kip1.METHODS: The proliferation of HepG2 cells was evaluated with MTT assay, and the cell cycle profile and apoptosis were assessed by cell morphology, DNA fragmentation analysis and flow cytometry. HepG2 cells were transfected with p27kip1 wild type by using Lipofectamine (LF2000), and the expression and subcellular localization of p27kip1 in HepG2were detected by immunocytochemistry.RESULTS: 60Co γ-irradiation inhibited the growth of HepG2cells in a dose-dependent manner. Apoptosis of HepG2 cells was induced 48 h after γ ray exposure. Furthermore research was carried out to induce exogenous expression of p27kip1in HepG2. The expression of p27kip1 induced G0/G1 phase arrest in HepG2 cells. The overexpression of p27kip1 enhanced 60Co γ-irradiation-induced radiosensitivity in HepG2 cells.CONCLUSION: Overexpression of p27kip1 is a rational approach to improve conventional radiotherapy outcomes, which may be a possible strategy for human hepatoma therapy.

  2. RBE values and repair characteristics for colo-rectal injury after caesium 137 gamma-ray and neutron irradiation. 2. Fractionation up to ten doses

    Energy Technology Data Exchange (ETDEWEB)

    Terry, N.H.A.; Denekamp, J. (Mount Vernon Hospital, Northwood (UK). Gray Lab.)

    1984-07-01

    Early and late colo-rectal damage in mice have been assessed after /sup 137/Cs ..gamma.. irradiation and 3 MeV neutrons given as 1, 2, 5 or 10 fractions. Damage was measured by early changes in body weight, the late production of short faecal pellets and the pattern of lethality after irradiation. The data have been analysed in terms of the time course of expression of damage, fractionation effects and the RBE for neutrons over a wide range of doses per fraction (0.5-12.5 Gy neutrons, 3.5-33.5 Gy ..gamma.. rays). The RBE was strongly dependent on dose per fraction because of the lack of reparable damage after neutrons. The RBE for both early and late effects was 5.0 at a neutron dose per fraction of 1 Gy. Extrapolation of the RBE data to lower doses, using the linear quadratic model, predicts a higher RBE for late (7.4-12.7) than for early damage (5.7-8.5) if ..gamma..-ray doses below 5 Gy are used.

  3. Analysis of the frequency of unstable chromosome aberrations in human lymphocytes irradiated with {sup 60}Co; Analise da frequencia de alteracoes cromossomicas instaveis em linfocitos humanos irradiados com {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Mendonca, Julyanne C.G.; Mendes, Mariana E.; Lima, Fabiana F., E-mail: july_cgm@hotmail.com, E-mail: mendes_sb@hotmail.com [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Santos, Neide, E-mail: santos_neide@yahoo.com.br [Universidade Federal de Pernambuco (CCB/UFPE), Recife, PE (Brazil). Departamento de Genetica

    2013-07-01

    The aim of this study was to analyze the frequency of unstable chromosomal aberrations induced by gamma radiation from a {sup 60}Co source at two different doses. Samples were obtained from a healthy donor and exposed to {sup 60}Co source (Gammacel 220 ) located in the Department of Nuclear Energy of Pernambuco Federal University (DEN/UFPe/Brazil) with a rate of air Kerma to 3,277 Gy/h. Exposures resulted in absorbed dose 0.51 Gy and 0.77 Gy. Mitotic metaphases were obtained by culturing lymphocytes for chromosome analysis and the slides were stained with 5% Giemsa. Among the unstable chromosomal aberrations the dicentric chromosomes, ring chromosomes and acentric fragments were analyzed. To calculate the significance level the chi - square test was used, considering relevant differences between the frequencies when the value of p < 0.05. To calculate the significance level of the chi - square test was used, considering relevant differences between the frequencies when the value of p < 0.05. The results showed that there was significant difference of the frequencies of dicentric chromosomes (from 0.18 to 0.51 to 0.37 Gy to 0.77 Gy), however there was no statistically significant difference between the frequencies of acentric fragments ( 0.054 to 0, 51 Gy to 0.063 to 0.77 Gy) and ring chromosomes (0.001 to 0.51 Gy to 0.003 to 0.77 Gy). The low number of rings is found justified, considering that in irradiated human lymphocytes, its appearance is rare relative to dicentrics. The results confirm that dicentrics are the most reliable biomarkers in estimating dose after exposure to gamma radiation. These two points will make the calibration curve dose-response being built for Biological Dosimetry Laboratory of CRCN-NE/CNEN.

  4. Differential gene expression in human fibroblasts after alpha-particle emitter (211)At compared with (60)Co irradiation

    DEFF Research Database (Denmark)

    Danielsson, Anna; Claesson, Kristina; Parris, Toshima Z;

    2013-01-01

    trastuzumab monoclonal antibody (0.25, 0.5, and 1 Gy) and (60)Co (1, 2, and 3 Gy). Results: We report gene expression profiles that distinguish the effect different radiation qualities and absorbed doses have on cellular functions in human fibroblasts. In addition, we identified commonly expressed transcripts...

  5. Assessment of gamma ray-induced DNA damage in Lasioderma serricorne using the comet assay

    Science.gov (United States)

    Kameya, Hiromi; Miyanoshita, Akihiro; Imamura, Taro; Todoriki, Setsuko

    2012-03-01

    We attempted a DNA comet assay under alkaline conditions to verify the irradiation treatment of pests. Lasioderma serricorne (Fabricius) were chosen as test insects and irradiated with gamma rays from a 60Co source at 1 kGy. We conducted the comet assay immediately after irradiation and over time for 7 day. Severe DNA fragmentation in L. serricorne cells was observed just after irradiation and the damage was repaired during the post-irradiation period in a time-dependent manner. The parameters of the comet image analysis were calculated, and the degree of DNA damage and repair were evaluated. Values for the Ratio (a percentage determined by fluorescence in the damaged area to overall luminance, including intact DNA and the damaged area of a comet image) of individual cells showed that no cells in the irradiated group were included in the Ratiocomet assay under alkaline conditions, combined with comet image analysis, can be used to identify irradiation history.

  6. Time-resolved dose evaluation in an X- and gamma-ray irradiated silver-activated glass detector for three-dimensional imaging applications

    Energy Technology Data Exchange (ETDEWEB)

    Kurobori, T., E-mail: kurobori@staff.kanazawa-u.ac.jp [Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa 920-1192 (Japan); Itoi, H. [Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa 920-1192 (Japan); Yanagida, Y. [Oarai Research Center, Chiyoda Technol Corporation, Oarai 311-1313 (Japan); Chen, Y.Q. [China Techwin Co., Ltd, Dongguan, Guangdong 523467 (China)

    2015-09-01

    Ag-activated phosphate glass based on the radiophotoluminescence (RPL) phenomenon has been used as the most commonly known RPL material and as an accumulated-type passive detector. In this work, the transient-state evaluation of the dose distributions achieved by X- and gamma-ray irradiations within the Ag-activated phosphate glass was performed using a time-resolved technique for the first time. Specifically, the blue RPL intensity ascribed to the electron-trapped Ag{sup 0} centres as a function of the depth at the vicinity of the surface was investigated for different types of radiation and a wide range of energies. In addition, the dose distributions at each layer within the glass confirmed by the time-resolved measurement were compared with those reconstructed by a disk-type transparent glass detector based on the blue RPL with a diameter of 100 mm. - Highlights: • The time-resolved dose evaluation of Ag-activated glass was performed. • The RPL intensity as a function of the depth was investigated for X- and gamma-rays. • The origin and mechanisms for the RPL enhancement in the near-surface layers were discussed.

  7. Effects of 60 Co-γ Ray Irradiation on the Seed Germination and Seedling Growth of Bauhinia variegata%60Co-γ辐照对洋紫荆种子发芽及幼苗生长的影响

    Institute of Scientific and Technical Information of China (English)

    徐佳琦; 戚嘉敏; 朱雯; 许逸林; 奚如春

    2016-01-01

    Different doses(0, 20, 40, 60, 80, 100 Gy) of 60Co-γ ray irradiation were applied to the dry Bauhinia variegata seeds and the effects on seed germination and seedling growth were investigated to explore the mutagenic effects of radiation. The results showed that with the increase of radiation the seed germination rate decreased first and rise again, decreasing from 51.66%(20 Gy) to 42.66%(60 Gy) and rising to 54.33%(100 Gy) after 6 months. Irradiation can promote the growth of the radical, the radical increased from 2.49 cm in the control group to 3.28 cm. Seed germination rate and seedling survival rate were reduced in the irradiation treatment of 40~60 Gy. The inhibition effect on seedling height and its ground diameter growth were found by radiation after seedling grew for six months. Also, the inhibition effect were found on the angle of leaf. However, no obvious deformity in the seedling morphology was found.%分别采用0,20,40,60,80,100 Gy 剂量的60Co-γ射线辐射洋紫荆(Bauhinia variegata)种子,观察测定其种子发芽率和幼苗生长指标,研究辐照对洋紫荆种子的诱变效应。结果表明,在0~100 Gy 辐射剂量内,随着辐照剂量的增加,洋紫荆种子发芽率出现先下降再上升的趋势,由51.66%(20 Gy)降至42.66%(60 Gy),又升高至54.33%(100 Gy)。一定剂量的辐照能促进胚根的生长,其中20 Gy 的辐射下平均胚根长度为3.28 cm,显著大于对照组(2.49 cm)(P<0.05)。40~60 Gy 辐射剂量使种子发芽率和幼苗成活率降低。各辐照处理对幼苗苗高、地径生长具有明显抑制作用,幼苗生长6个月后,各辐照组苗高、地径均显著小于对照组(P<0.05),同时对叶片分裂角度也具有一定的抑制作用但幼苗未出现致畸形态。

  8. Proteomics study of progeny of normal human liver cells irradiated by 60Coγ-rays%60Coγ射线照射后人肝细胞子代克隆的蛋白质组学研究

    Institute of Scientific and Technical Information of China (English)

    左雅慧; 王放; 王小莉; 李建国; 王仲文; 童建

    2009-01-01

    目的 探讨经不同剂量60C0 γ射线照射人正常肝细胞后子代克隆的蛋白质表达图谱变化,并对受照射后肝细胞子代的差异蛋白进行质谱鉴定.方法 人正常肝细胞7702分别经不同剂量60Coγ射线照射后,存活细胞克隆继续传代培养至40代,提取细胞总蛋白,进行双向电泳测定,凝胶银染和考染显色,用[mageMaster 2D Platium 510软件对获得的蛋白图谱加以分析,寻找差异表达的蛋白质.选取差异点,胶内原位酶解后进行MALDI-TOF分析和数据库搜索.结果 与对照组相比,各剂量点双向电泳图谱共发现2倍以上差异蛋白质点42个,上调10个,下调32个.成功鉴定出了17个共同差异表达蛋白,这些差异蛋白包括翻译控制肿瘤蛋白、热休克蛋白、氯离子通道蛋白、真核翻译起始因子等.结论 不同剂量的照射可导致人肝细胞子代克隆蛋白质图谱的改变,筛选出的差异蛋白可为探讨电离辐射诱发的基因组不稳定性及其分子机制提供实验依据和理论基础.%Objective To characterize the differential protein expression in the progeny of human liver ceils surviving from ionizing radiation by the proteomic analysis.Methods Two-dimensional electrophoresis gel coupled with mass spectrometry was used to explore the specific protein expression in the progeny of 7702 human liver cells surviving from ionizing radiation.Alterations in expression level of protein spots between the control and the progeny groups were statistically analyzed by ImageMaster 2D Platinum software and mass spectrometry was used to identify the protein spots with significantly altered expression-level.Results The progeny of irradiated ceils were derived from human liver cell line exposed to 0,2,4,6 Gy of 60Co γ-irradiatian.A total of 42 differentially expressed proteins between the control and the progeny of the irradiated cells groups were screened,of which 17 were identified by matrix assistant laser desorption

  9. Replication of simian virus 40 in simian virus 40-transformed hamster kidney cells induced by mitomycin C or /sup 60/Co. gamma. irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Rakusanova, T.; Smales, W.P.; Kaplan, J.C.; Black, P.H.

    1978-07-15

    Several clones of simian virus 40 (SV40)-transformed hamster kidney cells, which are heterogeneous for induction of infectious SV40, have been studied. SV40 yields are low after induction with /sup 60/Co ..gamma.. irradiation or mitomycin C. In order to clarify the mechanism(s) by which virus is produced in induced cells, we analyzed the replication of viral DNA and production of virion (V) antigen and infectious virus after induction in various clones as well as in lytically infected permissive cells. Cells replicating SV40 DNA or synthesizing V antigen were visualized by in situ hybridization and immunofluorescence techniques, respectively. Only some cells in induced cultures were found to produce SV40 and those which did were less efficient than lytically infected monkey cells. Mitomycin C or /sup 60/Co ..gamma.. irradiation acted by inducing more cells to replicate virus rather than by increasing the amount of SV40 released from individual cells. A greater proportion of cells could be induced to replicate SV40 DNA than to synthesize V antigen in all induced clones studied. Also, SV40 DNA replication was induced at lower doses of ..gamma.. irradiation than the production of either V antigen or infectious virus suggesting that synthesis of late virus protein is more restricted in induced cells than is replication of SV40 DNA. These findings indicate that one of the effects of induction treatments on SV40-transformed hamster cells is an enhancement of the cells' capacity to support SV40 replication.

  10. Radionuclides release from re-irradiated fuel under high temperature and pressure conditions. Gamma-ray measurements of VEGA-5 test

    Energy Technology Data Exchange (ETDEWEB)

    Hidaka, Akihide; Kudo, Tamotsu; Nakamura, Takehiko; Kanazawa, Toru; Kiuchi, Toshio; Uetsuka, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-03-01

    The VEGA (Verification Experiments of radionuclides Gas/Aerosol release) program is being performed at JAERI to clarify mechanisms of radionuclides release from irradiated fuel during severe accidents and to improve source term predictability. The fifth VEGA-5 test was conducted in January 2002 to confirm the reproducibility of decrease in cesium release under elevated pressure that was observed in the VEGA-2 test and to investigate the release behavior of short-life radionuclides. The PWR fuel of 47 GWd/tU after about 8.2 years of cooling was re-irradiated at Nuclear Safety Research Reactor (NSRR) for 8 hours before the heat-up test. After that, the two pellets of 10.9 g without cladding were heated up to about 2,900 K at 1.0 MPa under the inert He condition. The experiment reconfirmed the decrease in cesium release rate under the elevated pressure. The release data on short-life radionuclides such as Ru-103, Ba-140 and Xe-133 that have never been observed in the previous VEGA tests without re-irradiation was obtained using the {gamma} ray measurement. (author)

  11. Biological dose estimation for accidental supra-high dose gamma-ray exposure

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y., E-mail: yingchen29@yahoo.com.cn [Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Haidian District, Beijing 100850 (China); Yan, X.K. [Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Haidian District, Beijing 100850 (China); Department of Radiation Safety, Beijing Institute of Nuclear and Chemical Safety, 14 Guan-cun, Dongcheng District, Beijing 100077 (China); Du, J.; Wang, Z.D.; Zhang, X.Q.; Zeng, F.G.; Zhou, P.K. [Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Haidian District, Beijing 100850 (China)

    2011-09-15

    To correctly estimate the biological dose of victims accidentally exposed to a very high dose of {sup 60}Co gamma-ray, a new dose-effect curve of chromosomal dicentrics/multicentrics and rings in the supra-high dose range was established. Peripheral blood from two healthy men was irradiated in vitro with doses of {sup 60}Co gamma-rays ranging from 6 to 22 Gy at a dose rate of 2.0 Gy/min. Lymphocytes were concentrated, cultured and harvested at 52 h, 68 h and 72 h. The numbers of dic + r were counted. The dose-effect curves were established and validated using comparisons with doses from the Tokai-mura accident and were then applied to two victims of supra-high dose exposure accident. The results indicated that there were no significant differences in chromosome aberration frequency among the different culture times from 52 h to 72 h. The 6-22 Gy dose-effect curve was fitted to a linear quadratic model Y = -2.269 + 0.776D - 7.868 x l0{sup -3}D{sup 2}. Using this mathematic model, the dose estimates were similar to data from Tokai-mura which were estimated by PCC ring. Whole body average doses of 9.7 Gy and 18.1 Gy for two victims in the Jining accident were satisfactorily given. We established and successfully applied a new dose-effect curve of chromosomal dicentrics plus ring (dic + r) after 6-22 Gy {gamma}-irradiation from a supra-high dose {sup 60}Co gamma-ray accident.

  12. Production of ochratoxin a by aspergillus ochraceus NRRL-3174 before and after exposures to /sup 60/Co irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Applegate, K.L.; Chipley, J.R.

    1976-03-01

    Spores from the toxigenic organism Aspergillus ochraceus NRRL-3174 were exposed to specific levels of gamma irradiation and then allowed to germinate on selected media. Increases in ochratoxin A production by irradiated, compared to non-irradiated, spores were observed after inoculation of spores onto a cracked red wheat or into a synthetic liquid medium. Variations in daily ochratoxin production were also observed for control and irradiated spore-derived cultures developing on both media, with maximum toxin production varying from 7 to 11 days of incubation. The most notable increases in ochratoxin A production occurred from cultures developing from spores having been irradiated with 10, 25, or 50 krad. Exposures to 400 or 600 krad resulted in complete inhibition of spore germination and, consequently, no ochratoxin production. Of the two substrates used, wheat and synthetic, the quantities of ochratoxin A produced were significantly lower in the synthetic media than on the natural substrate. Higher and more rapid toxin production occurred from spores having been irradiated with 10, 25, 50, and 100 krad than occurred from the non-irradiated control spores when grown on synthetic media. Cultures derived from spores having been exposed to 10, 25, and 50 krad produced significantly higher levels of ochratoxin A after 8 days of incubation on natural substrate than did the controls. Analysis of variance revealed that substrate, length of incubation, as well as irradiation levels all affected the time required to produce maximum levels of ochratoxin A.

  13. Differential Expression of Retrotransposon WIS 2-1A Response to Vacuum,Low-Energy N+ Implantation and 60Coγ-ray Irradiation in Wheat

    Institute of Scientific and Technical Information of China (English)

    ZHAO Huiru; GU Yunhong; YA Huiyuan; JIAO Zhen; QIN Guangyong

    2009-01-01

    Mutagenesis and retrotransposons have a close relationship,but little attention has been paid yet to the activity of rtrotransposons produced by physical mutagens. The variation of retrotransposon WIS 2-1A activity in wheat(Triticum aestivum L.)embryos at three different growth times(30 h,45 h and 60 h)was investigated after they had been treated with N+ implantation in a vacuum of 5x10-2 Pa and irradiation by 60Coγ-ray respectively.For each of the three growth times the expression of WIS 2-1A showed almost entirely a same trend of downregulation,upregulation,then downregulation,and upregulation again with the increase in dose of N+ implantation,but the expression appeared irregular with the increase in irradiation of 60Coγ-ray.In conclusion,the acutely activating effect of WIS 2-1A stimulated by vacuum and high dose N+ implantation within a shorter incubation time may provide a convenient tool to advance the research on mutagenic breeding and function genes.

  14. Investigations on the effect of gamma-ray irradiation on the gas sensing properties of SnO2 nanoparticles

    Science.gov (United States)

    Lavanya, N.; Sekar, C.; Anithaa, A. C.; Sudhan, N.; Asokan, K.; Bonavita, A.; Leonardi, S. G.; Neri, G.

    2016-09-01

    In recent years, SnO2 nanoparticles (NPs) have been subjected to various modifications in order to improve their performance in sensing and other applications. Here, we report the synthesis of SnO2 NPs by microwave irradiation, and subsequent exposure to gamma (γ) radiation at different doses (0-150 kGy) to induce desirable physico-chemical properties. The irradiated samples were characterized by x-ray powder diffraction (XRD), transmission electron microscopy (TEM and HR-TEM), and photoluminescence (PL) to evaluate the effect of γ-ray irradiation on their morphology and microstructure. The results revealed that the bulk crystal structure remained unchanged after irradiation, while the existence of defects and a damaged over-layer have been confirmed by PL and HR-TEM respectively. The influence of γ-irradiation on the electrical and CO sensing characteristics was also investigated in the temperature range between 150 and 400 °C. γ-irradiated SnO2 NP based resistive sensors showed better CO sensing characteristics (i.e. higher response and lower working temperature) compared to non-irradiated SnO2. Upon optimizing the γ-ray dose irradiation level and working temperature, a ten-fold enhancement in the response to CO has been achieved (R/R 0 = 12 to 50 ppm of CO in air) in 50 kGy irradiated SnO2 NP based sensors operating at 150 °C. A possible mechanism for the enhanced sensing performance of γ-irradiated SnO2 NPs has been proposed.

  15. Effects of prenatal /sup 60/Co irradiation on postnatal neural, learning, and hormonal development of the squirrel monkey

    Energy Technology Data Exchange (ETDEWEB)

    Ordy, J.M.; Brizzee, K.R.; Dunlap, W.P.; Knight, C.

    1982-02-01

    The goals of this study were to examine the effects of 0, 50, and 100 rad of /sup 60/Co administered prenatally on postnatal development of neuromuscular coordination, visual discrimination learning, spontaneous light-dark stabilimeter activity, plasma cortisol, and somatometric growth rates of diurnal squirrel monkeys from birth to 90 days. In terms of accuracy, completeness, and time required for performance of reflexes and neuromuscular coordination, the performance of 50- and 100-rad offspring was less accurate and poorly coordinated and required more time for completion to that of controls. In visual orientation, discrimination, and reversal learning, the percentage correct responses of the 50- and 100-rad offspring were significantly lower than those of controls. Spontaneous light-dark stabilimeter activity of 50- and 100-rad offspring was significantly higher in the dark session than that of controls. Plasma cortisol was significantly higher in 100-rad infants than in controls. Comparisons of somatometric growth rates indicated that postnatal head circumference, crown-rump length, and to a lesser extent body weight increased at significantly slower rates in 50- and 100-rad offspring. These findings should provide essential information for formulating and carrying out multivariate behavioral, biochemical, and morphometric assessments of low-dose effects on the brain of primate offspring within demonstrable dose-response curves.

  16. Structural and optical analysis of 60Co gamma-irradiated thin films of polycrystalline Ga10Se85Sn5

    Science.gov (United States)

    Ahmad, Shabir; Asokan, K.; Shahid Khan, Mohd.; Zulfequar, M.

    2015-12-01

    The present study focuses on the effects of gamma irradiation on structural and optical properties of polycrystalline Ga10Se85Sn5 thin films with a thickness of ∼300 nm deposited by the thermal evaporation technique on cleaned glass substrates. X-ray diffraction patterns of the investigated thin films show that crystallite growth occurs in the orthorhombic phase structure. The surface study carried out by using the scanning electron microscope (SEM) confirms that the grain size increases with gamma irradiation. The optical parameters were estimated from optical transmission spectra data measured from a UV-vis-spectrophotometer in the wavelength range of 200-1100 nm. The refractive index dispersion data of the investigated thin films follow the single oscillator model. The estimated values of static refractive index n0, oscillator strength Ed, zero frequency dielectric constant ε0, optical conductivity σoptical and the dissipation factor increases after irradiation, while the single oscillator energy Eo decreases after irradiation. It was found that the value of the optical band gap of the investigated thin films decreases and the corresponding absorption coefficient increases continuously with an increase in the dose of gamma irradiation. This post irradiation changes in the values of optical band gap and absorption coefficient were interpreted in terms of the bond distribution model.

  17. Measurement of characteristic prompt gamma rays emitted from oxygen and carbon in tissue-equivalent samples during proton beam irradiation

    OpenAIRE

    Polf, Jerimy C.; Panthi, Rajesh; Mackin, Dennis S; McCleskey, Matt; Saastamoinen, Antti; Roeder, Brian T; Beddar, Sam

    2013-01-01

    The purpose of this work was to characterize how prompt gamma (PG) emission from tissue changes as a function of carbon and oxygen concentration, and to assess the feasibility of determining elemental concentration in tissues irradiated with proton beams. For this study, four tissue-equivalent water-sucrose samples with differing densities and concentrations of carbon, hydrogen, and oxygen were irradiated with a 48 MeV proton pencil beam. The PG spectrum emitted from each sample was measured ...

  18. Optimization of process parameters for the inactivation of Lactobacillus sporogenes in tomato paste with ultrasound and 60Co- γ irradiation using response surface methodology

    Science.gov (United States)

    Ye, Sheng-Ying; Qiu, Yuan-Xin; Song, Xian-Liang; Luo, Shu-Can

    2009-03-01

    The processing parameters for ultrasound and 60Co- γ irradiation were optimized for their ability to inactivate Lactobacillus sporogenes in tomato paste using a systematic experimental design based on response surface methodology. Ultrasonic power, ultrasonic processing time and irradiation dose were explored and a central composite rotation design was adopted as the experimental plan, and a least-squares regression model was obtained. The significant influential factors for the inactivation rate of L. sporogenes were obtained from the quadratic model and the t-test analyses for each process parameter. Confirmation of the experimental results indicated that the proposed model was reasonably accurate and could be used to describe the efficacy of the treatments for inactivating L. sporogenes within the limits of the factors studied. The optimized processing parameters were found to be an ultrasonic power of 120 W with a processing time of 25 min and an irradiation dose of 6.5 kGy. These were measured under the constraints of parameter limitation, based on the Monte Carlo searching method and the quadratic model of the response surface methodology, including the a/ b value of the Hunter color scale of tomato paste. Nevertheless, the ultrasound treatment prior to irradiation for the inactivation of L. sporogenes in tomato paste was unsuitable for reducing the irradiation dose.

  19. Optimization of process parameters for the inactivation of Lactobacillus sporogenes in tomato paste with ultrasound and {sup 60}Co-{gamma} irradiation using response surface methodology

    Energy Technology Data Exchange (ETDEWEB)

    Ye Shengying [College of Food Science, South China Agricultural University, Wushan, Guangzhou, GD 510640 (China)], E-mail: yesy@scau.edu.cn; Qiu Yuanxin; Song Xianliang; Luo Shucan [College of Food Science, South China Agricultural University, Wushan, Guangzhou, GD 510640 (China)

    2009-03-15

    The processing parameters for ultrasound and {sup 60}Co-{gamma} irradiation were optimized for their ability to inactivate Lactobacillus sporogenes in tomato paste using a systematic experimental design based on response surface methodology. Ultrasonic power, ultrasonic processing time and irradiation dose were explored and a central composite rotation design was adopted as the experimental plan, and a least-squares regression model was obtained. The significant influential factors for the inactivation rate of L. sporogenes were obtained from the quadratic model and the t-test analyses for each process parameter. Confirmation of the experimental results indicated that the proposed model was reasonably accurate and could be used to describe the efficacy of the treatments for inactivating L. sporogenes within the limits of the factors studied. The optimized processing parameters were found to be an ultrasonic power of 120 W with a processing time of 25 min and an irradiation dose of 6.5 kGy. These were measured under the constraints of parameter limitation, based on the Monte Carlo searching method and the quadratic model of the response surface methodology, including the a/b value of the Hunter color scale of tomato paste. Nevertheless, the ultrasound treatment prior to irradiation for the inactivation of L. sporogenes in tomato paste was unsuitable for reducing the irradiation dose.

  20. Gamma ray camera

    Science.gov (United States)

    Perez-Mendez, V.

    1997-01-21

    A gamma ray camera is disclosed for detecting rays emanating from a radiation source such as an isotope. The gamma ray camera includes a sensor array formed of a visible light crystal for converting incident gamma rays to a plurality of corresponding visible light photons, and a photosensor array responsive to the visible light photons in order to form an electronic image of the radiation therefrom. The photosensor array is adapted to record an integrated amount of charge proportional to the incident gamma rays closest to it, and includes a transparent metallic layer, photodiode consisting of a p-i-n structure formed on one side of the transparent metallic layer, and comprising an upper p-type layer, an intermediate layer and a lower n-type layer. In the preferred mode, the scintillator crystal is composed essentially of a cesium iodide (CsI) crystal preferably doped with a predetermined amount impurity, and the p-type upper intermediate layers and said n-type layer are essentially composed of hydrogenated amorphous silicon (a-Si:H). The gamma ray camera further includes a collimator interposed between the radiation source and the sensor array, and a readout circuit formed on one side of the photosensor array. 6 figs.

  1. Gamma ray camera

    Science.gov (United States)

    Perez-Mendez, Victor

    1997-01-01

    A gamma ray camera for detecting rays emanating from a radiation source such as an isotope. The gamma ray camera includes a sensor array formed of a visible light crystal for converting incident gamma rays to a plurality of corresponding visible light photons, and a photosensor array responsive to the visible light photons in order to form an electronic image of the radiation therefrom. The photosensor array is adapted to record an integrated amount of charge proportional to the incident gamma rays closest to it, and includes a transparent metallic layer, photodiode consisting of a p-i-n structure formed on one side of the transparent metallic layer, and comprising an upper p-type layer, an intermediate layer and a lower n-type layer. In the preferred mode, the scintillator crystal is composed essentially of a cesium iodide (CsI) crystal preferably doped with a predetermined amount impurity, and the p-type upper intermediate layers and said n-type layer are essentially composed of hydrogenated amorphous silicon (a-Si:H). The gamma ray camera further includes a collimator interposed between the radiation source and the sensor array, and a readout circuit formed on one side of the photosensor array.

  2. 60Coγ射线辐照不同麻种种子的细胞学效应%Cytological Effects on Seeds of Hibiscus cannabinus and Cannabis sativa Irradiated by 60Coγ ray

    Institute of Scientific and Technical Information of China (English)

    周立人; 吴雪琴; 魏晓飞; 李布青

    2003-01-01

    通过5种不同剂量的60Coγ射线对两个不同麻种3个品种材料的种子辐照效应研究表明,低剂量的60Coγ射线辐照能促进麻类作物根尖细胞的有丝分裂.但随着γ射线辐照剂量的增加,根尖细胞有丝分裂指数呈不同程度的下降趋势.60Coγ射线辐照能诱发根尖细胞的染色体畸变和核畸变,出现桥、断片、落后染色体、微核、双核、小核等多种畸变类型,并且辐照剂量越大,根尖细胞畸变类型越多,变异频率越高.研究结果还表明不同麻种、同一麻种不同品种对60Coγ射线的辐射敏感性不同,红麻中杂红305最强,红麻福红2号次之,大麻最弱.

  3. Effects of Pre-exposure of Mouse Pituitary with Low-dose 60Co γ-ray on Male Reproductive Endocrine Capacity Induced by Subsequent High-dose Irradiation

    Institute of Scientific and Technical Information of China (English)

    ZhangHong; LiWenjian; JingXiaodong; LiuBing; MinFengling; ZhouQingming; XieYi

    2003-01-01

    To investigate the effects of pre-exposure of mouse pituitary with low-dose 60Co γ-ray on male reproductive endocrine capacity induced by subsequent high-dose irradiation, the pituitary of the B6C3F1 hybrid strain male mice were irradiated with 0.05 Gy of 60Co γ-ray as the pre-exposure dose (D1), and were then irradiated with 2 Gy of 60Co γ-ray as challenging irradiation dose (D2) at 4 h after per-exposure. Pituitary gonadotroping hormones --follicle-stimulating hormone (FSH) and luterinzing hormone (LH), serum testosterone, testis weight and sperm count were measured at 35th day after irradiation.

  4. Effects of neonatal. gamma. -ray irradiation on rat hippocampus: Pt. 2; Development of excitatory amino acid binding sites

    Energy Technology Data Exchange (ETDEWEB)

    Dessi, F.; Represa, A.; Ben-Ari, Y. (Institut National de la Sante et de la Recherche Medicale (INSERM), 75 - Paris (France))

    1991-01-01

    In the rat, neonatal irradiation produces a destruction of denate granule cells and prevents the development of the mossy fibre-CA3 pyramidal cell synapse. The developmental increase of high affinity kainate binding sites in the stratum lucidum was reduced on the irradiated side as compared with the control side. This suggests that a proportion of high affinity kainate binding sites is associated with mossy fibres. In contrast, the development profile of N-methyl-D-aspartate binding sites, which are associated with associational and commissural synapses in CA3, was not affected by irradiation. The role that afferent fibres may play in the development of pyramidal cells is discussed in connection with the modulatory effects of glutamate receptors on the development of neurons. (author).

  5. Toxoplasma gondii gamma irradiation using Co-60; Irradiacao do Toxoplasma gondii com gama do {sup 60} Co

    Energy Technology Data Exchange (ETDEWEB)

    Serra-Freire, Nicolau Maues [Universidade Federal Rural do Rio de Janeiro, RJ (Brazil). Dept. de Parasitologia Animal; Maliska, Carmelindo [Hospital Central do Exercito, Rio de Janeiro, RJ (Brazil). Servico de Medicina Nuclear; Norberg, Antonio Neres [Instituto de Biologia do Exercito (IBEx), Rio de Janeiro, RJ (Brazil)

    1996-07-01

    The use of nuclear power through radiation for the destruction of microorganisms which cause food deterioration, infections and toxicosis, is specifically for peaceful purposes. Toxoplasma gondii is a protozoa responsible for illnesses in humans and animals. One of the most common ways of transmission is through raw or poorly cooked meat. There is little information on the resistance of T. gondii to radiation. The objective of this research is to determine the Minimum Lethal Dose (MLD) of gamma radiation for those microorganisms. Suspensions of T. gondii containing approximately one million taquizoites/ml were irradiated with doses between up 0,01 up to 0,15 kGy (Kilogray) and inoculated to mice. The surviving T. gondii were re-irradiated with 0,01 up to 0,16 kGy. The irradiated protozoa were totally destroyed with a 0,15 kGy dose (MLD). Taquizoites issued from live protozoa of 0,14 kGy also were completely destroyed with dose of 0,15 kGy. No increase in resistance was observed regarding the non irradiated protozoa. (author)

  6. RBE values for colo-rectal injury after caesium 137 gamma-ray and neutron irradiation. 1. Single doses

    Energy Technology Data Exchange (ETDEWEB)

    Terry, N.H.A.; Denekamp, J.; Maughan, R.L. (Mount Vernon Hospital, Northwood (UK). Gray Lab.)

    1983-04-01

    Colo-rectal damage in mice has been assessed after caesium ..gamma.. irradiation and 3 MeV neutrons given as single doses. Several assays were used, including body weight changes, faecal deformity and lethality. Dose response curves were constructed for each assay at times ranging from 10 days to 16 months after irradiation. An initial loss of weight at 10-20 days was presumably related to epithelial denudation, but a dose-dependent weight reduction (compared with controls) persisted over the animals' life span. Mice died progressively after localised pelvic ..gamma.. irradiation; there was no sharp demarcation between an early and late phase of lethal injury. Death resulted from intestinal stricture or stenosis. The time course for lethality was qualitatively different after neutron irradiation, with little progression of damage between 5 and 11 months. Faecal deformity was detectable as a higher proportion of small pellets when the rectum became constricted by fibrosis. No significant faecal deformity was observed before 6 months after which time dose response curves could be obtained. The RBE for early damage (assessed at 1-3 months) was 2.2-2.7, falling to 1.7-1.9 for late damage (determined at 10-15 months) over the range of neutron doses of 7.5-12 Gy.

  7. 60Co γ-rays irradiation effect in DC performance of AlGaN/GaN high electron mobility transistors

    Institute of Scientific and Technical Information of China (English)

    Gu Wenping; Chen Chi; Duan Huantao; Hao Yue; Zhang Jincheng; Wang Chong; Feng Qian; Ma Xiaohua

    2009-01-01

    Unpassivated/passivated AlGaN/GaN high electron mobility transistors(HEMTs) were exposed to 1.25MeV60Co γ-rays at a dose of 1 Mrad(Si).The saturation drain current of the unpassivated devices decreased by 15%at 1 Mrad γ-dose,and the maximal transconductance decreased by 9.1% under the same condition;moreover,either forward or reverse gate bias current was significantly increased,while the threshold voltage is relatively unaffected.By sharp contrast,the passivated devices showed scarcely any change in saturation drain current and maximal transconductance at the same γ dose.Based on the differences between the passivated HEMTs and unpassivated HEMTs,adding the C-V measurement results,the obviously parameter degradation of the unpassivated AlGaN/GaN HEMTs is believed to be caused by the creation of electronegative surface state charges in source-gate spacer and gate-drain spacer at the low dose (1 Mrad).These results reveal that the passivation is effective in reducing the effects of surface state charges induced by the 60Co γ-rays irradiation.so the passivation is an effective reinforced approach.

  8. SVOM gamma ray monitor

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The space-based multi-band astronomical Variable Object Monitor(SVOM) mission is dedicated to the detection,localization and broad-band study of gamma-ray bursts(GRBs) and other high-energy transient phenomena.The gamma ray monitor(GRM) onboard is designed to observe GRBs up to 5 MeV.With this instrument,one of the key GRB parameters,Epeak,can be easily measured in the hard X-ray band.It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  9. SVOM Gamma Ray Monitor

    CERN Document Server

    Dong, Yongwei; Li, Yanguo; Zhang, Yongjie; Zhang, Shuangnan

    2009-01-01

    The Space-based multi-band astronomical Variable Object Monitor (SVOM) mission is dedicated to the detection, localization and broad-band study of Gamma-Ray Bursts (GRBs) and other high-energy transient phenomena. The Gamma Ray Monitor (GRM) onboard is designed to observe the GRBs up to 5 MeV. With this instrument one of the key GRB parameter, Epeak, can be easily measured in the hard x-ray band. It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  10. Use of delayed gamma rays for active non-destructive assay of {sup 235}U irradiated by pulsed neutron source (plasma focus)

    Energy Technology Data Exchange (ETDEWEB)

    Andola, Sanjay; Niranjan, Ram [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Kaushik, T.C., E-mail: tckk@barc.gov.in [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Rout, R.K. [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Kumar, Ashwani; Paranjape, D.B.; Kumar, Pradeep; Tomar, B.S.; Ramakumar, K.L. [Radioanalytical Chemistry Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Gupta, S.C. [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India)

    2014-07-01

    A pulsed neutron source based on plasma focus device has been used for active interrogation and assay of {sup 235}U by monitoring its delayed high energy γ-rays. The method involves irradiation of fissile material by thermal neutrons obtained after moderation of a burst of neutrons emitted upon fusion of deuterium in plasma focus (PF) device. The delayed gamma rays emitted from the fissile material as a consequence of induced fission were detected by a large volume sodium iodide (NaI(Tl)) detector. The detector is coupled to a data acquisition system of 2k input size with 2k ADC conversion gain. Counting was carried out in pulse height analysis mode for time integrated counts up to 100 s while the temporal profile of delayed gamma has been obtained by counting in multichannel scaling mode with dwell time of 50 ms. To avoid the effect of passive (natural) and active (from surrounding materials) backgrounds, counts have been acquired for gamma energy between 3 and 10 MeV. The lower limit of detection of {sup 235}U in the oxide samples with this set-up is estimated to be 14 mg.

  11. Effects of gamma-ray irradiation on interspecific hybridization between Chamaecyparis obtusa S. et Z. and Chamaecyparis pisifera S. et Z

    Energy Technology Data Exchange (ETDEWEB)

    Maeta, Takehiko (Institute of Radiation Breeding, Omiya, Ibaraki (Japan))

    1982-03-01

    C. obtusa S. et Z. is one of the most important forest trees in Japan, and possesses high wood quality. It adapts to dry or semi-dry planting sites, but when it is planted in humid and productive soil, physiological damage is often seen, and its woods are not resistant against termite harm. On the contrary, C. pisifera S. et Z. has high adaptability to humid and productive soil, and is resistant against termite harm. In order to improve the resistance of C. obtusa against diseases and insects, an attempt to obtain a hybrid between C. obtusa and C. pisifera has been made. However, it was found to be very difficult to obtain the hybrid because of low cross compatibility. Therefore, the radiosensitivity of reproductive organs and the induction of mutation in C. obtusa and C. pisifera, the cause of interspecific incompatibility between both species, and the possibility of breaking down the incompatibility were investigated. Also, the cytological screening of the hybrids between C. obtusa and C. pisifera was made. It was considered that the acute gamma-ray irradiation from 500 to 600 R on male flowers was optimum for the hybridization of the present purpose. All of the hybrids produced in this study were triploid.

  12. Standard test method for determining the content of cesium-137 in irradiated nuclear fuels by high-resolution gamma-ray spectral analysis

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2008-01-01

    1.1 This test method covers the determination of the number of atoms of 137Cs in aqueous solutions of irradiated uranium and plutonium nuclear fuel. When combined with a method for determining the initial number of fissile atoms in the fuel, the results of this analysis allows atom percent fission (burn-up) to be calculated (1). The determination of atom percent fission, uranium and plutonium concentrations, and isotopic abundances are covered in Test Methods E 267 and E 321. 1.2 137Cs is not suitable as a fission monitor for samples that may have lost cesium during reactor operation. For example, a large temperature gradient enhances 137Cs migration from the fuel region to cooler regions such as the radial fuel-clad gap, or, to a lesser extent, towards the axial fuel end. 1.3 A nonuniform 137Cs distribution should alert the analyst to the potential loss of the fission product nuclide. The 137Cs distribution may be ascertained by an axial gamma-ray scan of the fuel element to be assayed. In a mixed-oxide fu...

  13. Characterization by EPR of radicals in HDPE, PA6 and HDPE/PA6 blend irradiated with gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Silva, P. [Centro de Fisica, Instituto Venezolano de Investigacion Cientifica IVIC, Carretera Panamericana Km. 11, A.P. 21827, Caracas 1020-A (Venezuela); Albano, C.; Lovera, D. [Centro de Quimica, IVIC (Venezuela); Perera, R. [Departamento de Mecanica, Universidad Simon Bolivar, Caracas (Venezuela)

    2003-07-01

    Using electron paramagnetic resonance (EPR), we studied the tree radical formation in high-density Polyethylene (HDPE), polyamide (PA6) and HDPE/PA6 (80/20)blend, irradiated with integral doses (D), 0 < D < 1000 KGy, with a dose rate of irradiation in air of 6.6 KGy/h. Typical spectra indicative of the formation of allyl, alkyl and poly enyl radicals were obtained. A decay in the total number of spins per gram (C/g), when the samples are aged by a period of time of 30 days, was found, which is typical of a recombination of radicals with their environment. Additionally, a different order fit for the C/g as a function of D was obtained, which is indicative of the complex behavior of the kinetics of the decomposition. (Author)

  14. Gamma Ray Astronomy

    Science.gov (United States)

    Wu, S. T.

    2000-01-01

    The project has progressed successfully during this period of performance. The highlights of the Gamma Ray Astronomy teams efforts are: (1) Support daily BATSE data operations, including receipt, archival and dissemination of data, quick-look science analysis, rapid gamma-ray burst and transient monitoring and response efforts, instrument state-of-health monitoring, and instrument commanding and configuration; (2) On-going scientific analysis, including production and maintenance of gamma-ray burst, pulsed source and occultation source catalogs, gamma-ray burst spectroscopy, studies of the properties of pulsars and black holes, and long-term monitoring of hard x-ray sources; (3) Maintenance and continuous improvement of BATSE instrument response and calibration data bases; (4) Investigation of the use of solid state detectors for eventual application and instrument to perform all sky monitoring of X-Ray and Gamma sources with high sensitivity; and (5) Support of BATSE outreach activities, including seminars, colloquia and World Wide Web pages. The highlights of this efforts can be summarized in the publications and presentation list.

  15. {sup 60}Co gamma-irradiation effects on electrical properties of a rectifying diode based on a novel macrocyclic Zn octaamide complex

    Energy Technology Data Exchange (ETDEWEB)

    Ocak, Y.S. [Department of Science, Faculty of Education, University of Dicle, Diyarbakir (Turkey); Kilicoglu, T., E-mail: kilicoglutahsin@gmail.co [Department of Physics, Faculty of Art and Science, University of Batman, Batman (Turkey); Department of Physics, Faculty of Art and Science, University of Dicle, Diyarbakir (Turkey); Topal, G. [Department of Chemistry, Faculty of Education, University of Dicle, Diyarbakir (Turkey); Baskan, M.H. [Department of Physics, Faculty of Education, University of Dicle, Diyarbakir (Turkey)

    2010-01-01

    C{sub 36}H{sub 28}N{sub 12}O{sub 8}ZnCl{sub 2}.9/2H{sub 2}O, Zn-octaamide (ZnOA) macrocyclic compound was synthesized to be used in the fabrication of electronic and photoelectronic devices. The structure of new compound was identified by using {sup 1}H NMR, {sup 13}C NMR, IR, UV-vis and LC-MS spectroscopic methods. The Sn/ZnOA/n-Si/Au structure was engineered by forming a thin macrocyclic organic compound layer on n-Si inorganic substrate and then by evaporating Sn metal on the organic layer. It was seen that the device had a good rectifying behaviour and showed Schottky diode properties. The diode was irradiated under {sup 60}Co gamma-source at room temperature. Characteristic parameters of the diode were determined from its current-voltage (I-V) and capacitance voltage (C-V) measurements before and after irradiation. It was observed that gamma-irradiation had clear effects on I-V and C-V properties. Also, it was seen that the barrier height, the ideality factor and the series resistance values decreased after the applied radiation, while the saturation current value increased.

  16. Effect of pelvic irradiation of lactose absorption. [. gamma. rays or x rays were used in gynecologic malignancy therapy

    Energy Technology Data Exchange (ETDEWEB)

    Stryker, J.A.; Mortel, R.; Hepner, G.W.

    1978-01-01

    Twenty-four patients undergoing pelvic irradiation for gynecologic malignancies had /sup 14/C-lactose breath tests performed in the first and fifth weeks of their treatment. The /sup 14/C-lactose breath test was performed by administering 2 ..mu..Ci of /sup 14/C-lactose by mouth along with 50 g of lactose. Breath samples were collected in ethanolic hyamine 1, 2, and 3 hr later; the radioactivity of the trapped /sup 14/CO/sub 2/ was determined by liquid scintillation spectroscopy. In the first week of treatment the percentage of administered /sup 14/C excreted as /sup 14/CO/sub 2/ at 1, 2, and 3 hr was 1.7 +- 0.8% (mean +- SD), 4.5 +- 1.6%, and 5.8 +- 1.4%, respectively. In the fifth week of treatment the 1-hr, 2-hr, and 3-hr values were 1.2 +- 0.9%, 3.6 +- 2.0%, and 4.7 +- 1.9%, respectively. The difference between the first week and fifth week test results at 1, 2, and 3 hr was statistically significant (t = 2.64, p < 0.02), (t = 2.24, p < 0.05), (t = 2.95, p < 0.01). There was a negative correlation between the 1-hr /sup 14/C-lactose breath test results in the fifth week and the stool frequency at that time (r = -0.44, p < 0.05). Seven of 12 patients whose 1 hr /sup 14/C-lactose breath test results in the fifth week were below normal (<1.2%) had nausea at that time. The data suggest that in some patients, lactose malabsorption as a result of the effect of radiation on small intestinal function may be etiologically related to the symptoms of nausea and diarrhea which occur commonly in patients who are undergoing pelvic irradiation. In addition, the results suggest that lactose-containing foods should be restricted in some patients who are undergoing pelvic irradiation to prevent symptoms resulting from radiation-induced lactose intolerance.

  17. Effect of gamma-ray irradiated natural herbal extracts on NF-kB activation in HMC-1 cells

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yong Soo; Lim, Youn Mook; Gwon, Hui Jeong; Choi, Bo Ram; Nho, Young Chang [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2009-12-15

    Recently, studies have documented various health benefits of some natural herbal extracts (NHE) such as Houttuynia cordata (H), Centella asiatica (C), Plantago asiatica (P), Morus alba L. (M), and Ulmus davidiana (U). The aim of the present study was to demonstrate the radiation effect on NF-kB activation of the NHE in the human mast cell line (HMC-1). The HMC-1 cells were stimulated with phorbol 12-myristate 13-acetate (PMA) plus A23187. Both non-and irradiated NHE also significantly inhibited the PMA plus A23187-induced nuclear factor NF-kB activation and also suppressed the expression of activation of NF-kB. These results indicated that the NHE exerted a regulatory effect on inflammatory reactions mediated by mast cells.

  18. Formation of radical cations and dose response of alpha-terthiophene-cellulose triacetate films irradiated by electrons and gamma rays

    CERN Document Server

    Emmi, S S; Ceroni, P; D'Angelantonio, M; Lavalle, M; Fuochi, P G; Kovács, A

    2002-01-01

    The radiation-induced UV-vis spectrum of alpha-terthiophene radical cation in solid is reported. The radical cation initiates an oligomerization in the CTA matrix producing permanently coloured conjugated polarons. The specific net absorbance at 465 nm is linearly related with dose up to 2x10 sup sup 6 sup sup G y, for electrons and gamma irradiation. The decrease of the UV typical absorption (355 nm) and of four IR bands of alpha-terthiophene is linear with dose, as well. Although sensitivity is influenced by dose rate, it turned out that a linear relationship holds between sensitivity and log dose rate, in the range from 2 to 10 sup sup 5 Gy, min. These findings suggest a potential application of the system for dosimetric purposes over a wide range of dose and dose rate.

  19. Evaluation of components of X-ray irradiated 7-valent pneumococcal conjugate vaccine and pneumococcal vaccine polyvalent and X-ray and gamma-ray irradiated acellular pertussis component of DTaP vaccine products

    Energy Technology Data Exchange (ETDEWEB)

    May, J.C. E-mail: may@cber.fda.gov; Rey, L. E-mail: louis.rey@bluewin.ch; Lee, C.-J.; Arciniega, Juan

    2004-10-01

    Samples of pneumococcal vaccine polyvalent, 7-valent pneumococcal conjugate vaccine, and two different diphtheria and tetanus toxoids and acellular pertussis vaccines adsorbed were irradiated with X-rays and/or gamma-rays (Co-60). Mouse IgG and IgM antibody responses (ELISA) for types 9V, 14, 18C, and 19F pneumococcal polysaccharides and conjugates indicated that the polysaccharides were more tolerant of the radiation than the conjugates. The mouse antibody response for the detoxified pertussis toxin (PT) antigen, filamentous hemagglutinin antigen (FHA), pertactin (PRN), and fimbriae types 2 and 3 (FIM) antigens for the appropriate vaccine type indicated that the antibody response was not significantly changed in the 25 kGy X-ray irradiated vaccines frozen in liquid nitrogen compared to the control vaccine.

  20. Evaluation of components of X-ray irradiated 7-valent pneumococcal conjugate vaccine and pneumococcal vaccine polyvalent and X-ray and gamma-ray irradiated acellular pertussis component of DTaP vaccine products

    Science.gov (United States)

    May, J. C.; Rey, L.; Lee, Chi-Jen; Arciniega, Juan

    2004-09-01

    Samples of pneumococcal vaccine polyvalent, 7-valent pneumococcal conjugate vaccine, and two different diphtheria and tetanus toxoids and acellular pertussis vaccines adsorbed were irradiated with X-rays and/or gamma-rays (Co-60). Mouse IgG and IgM antibody responses (ELISA) for types 9V, 14, 18C, and 19F pneumococcal polysaccharides and conjugates indicated that the polysaccharides were more tolerant of the radiation than the conjugates. The mouse antibody response for the detoxified pertussis toxin (PT) antigen, filamentous hemagglutinin antigen (FHA), pertactin (PRN), and fimbriae types 2 and 3 (FIM) antigens for the appropriate vaccine type indicated that the antibody response was not significantly changed in the 25 kGy X-ray irradiated vaccines frozen in liquid nitrogen compared to the control vaccine.

  1. Gamma rays from Galactic pulsars

    OpenAIRE

    2014-01-01

    Gamma rays from young pulsars and milli-second pulsars are expected to contribute to the diffuse gamma-ray emission measured by the {\\it Fermi} Large Area Telescope (LAT) at high latitudes. We derive the contribution of the pulsars undetected counterpart by using information from radio to gamma rays and we show that they explain only a small fraction of the isotropic diffuse gamma-ray background.

  2. Effects of Pre-exposure Mouse Pituitary with Low-dose 60Co γ-ray on Growth Hormone (GH) and Body Mass Induced by Subsequent High-dose Irradiation

    Institute of Scientific and Technical Information of China (English)

    ZhangHong; LiWenjian; JingXiaodong; LiuBing; MinFengling; ZhouQingming; XieYi

    2003-01-01

    The pituitary of the B6C3F1 hybrid strain mice were irradiated with 0.05 Gy of 60Co γ-ray as the pre-exposure dose (D1), and were then irradiated with 2 Gy of 60Co γ-ray as challenging irradiation dose (D2) at 4h after per-exposure. Body weight and serum growth hormone (GH) were measured at 35th day after irradiation. The results showed that irradiation of mouse testes with 2 Gy of 60Co γ-ray significantly diminished mousebody weight and level of serum GH (Table). Pre-exposure with a low-dose (0.05 Gy) of 60Co γ-ray significantly alleviated reductions of mouse body weight and level of serum GH induced by subsequent a high-dose (2 Gy) irradiation (Table). The data suggested that low-dose ionizing irradiation can induce adaptive responses to the harmful effects of pituitary by subsequent high-dose exposure.

  3. Measurements of neutron distribution in neutrons-gamma-rays mixed field using imaging plate for neutron capture therapy.

    Science.gov (United States)

    Tanaka, Kenichi; Endo, Satoru; Hoshi, Masaharu

    2010-01-01

    The imaging plate (IP) technique is tried to be used as a handy method to measure the spatial neutron distribution via the (157)Gd(n,gamma)(158)Gd reaction for neutron capture therapy (NCT). For this purpose, IP is set in a water phantom and irradiated in a mixed field of neutrons and gamma-rays. The Hiroshima University Radiobiological Research Accelerator is utilized for this experiment. The neutrons are moderated with 20-cm-thick D(2)O to obtain suitable neutron field for NCT. The signal for IP doped with Gd as a neutron-response enhancer is subtracted with its contribution by gamma-rays, which was estimated using IP without Gd. The gamma-ray response of Gd-doped IP to non-Gd IP is set at 1.34, the value measured for (60)Co gamma-rays, in estimating the gamma-ray contribution to Gd-doped IP signal. Then measured distribution of the (157)Gd(n,gamma)(158)Gd reaction rate agrees within 10% with the calculated value based on the method that has already been validated for its reproducibility of Au activation. However, the evaluated distribution of the (157)Gd(n,gamma)(158)Gd reaction rate is so sensitive to gamma-ray energy, e.g. the discrepancy of the (157)Gd(n,gamma)(158)Gd reaction rate between measurement and calculation becomes 30% for the photon energy change from 33keV to 1.253MeV.

  4. Thermoluminescence (TL) Analysis and Fading Studies of Naturally Occurring Salt Irradiated by 500 mGy Gamma Rays

    Science.gov (United States)

    Tiwari, Ramesh Chandra; Pau, Kham Suan

    2011-10-01

    The aim of the present study was to investigate the potential of the naturally occurring salt for the dosimetry purposes, using TL. The fine powder samples (20 mg) were irradiated by γ- rays from 500 mGy to 2500 mGy by using Theratron-780C Cobalt-60 source, however, this paper discusses about 500 mGy only. The TL glow curve peak parameters were studied by using Chen's peak shape equation. TL glow curves were compared with fitted curves using glow curve deconvolution (GCD) method by using Kitis expression. The kinetic parameter values (E, b and s) so calculated, are in good agreement with those available in literature. The calculated energy values were also verified by using various heating rate (VHR) method. χ2 test and figure of merit (FOM) calculation was done to accept the goodness of fit between the curves. Fading studies of the sample showed a good fitting between the curves. The analysis suggests that natural salt should be considered for dosimetry purposes.

  5. Poly(acrylic acid)/polyethylene glycol hygrogel prepared by using gamma-ray irradiation for mucosa adhesion

    Energy Technology Data Exchange (ETDEWEB)

    Nho, Young-Chang; Park, Jong-Seok; Shin, Jung-Woong; Lim, Youn-Mook; Jeong, Sung-In; Shin, Young-Min; Gwon, Hui-Jeong [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of); Khil, Myung-Seob [Chonbuk National University, Jeonju (Korea, Republic of); Lee, Deok-Won [Maxillofacial Surgery Dental Hospital, Seoul (Korea, Republic of); Ahn, Sung-Jun [JADAM Co., LTD., Seogwipo (Korea, Republic of)

    2015-01-15

    A buccal delivery system provides a much milder environment for drug delivery compared to an oral delivery which presents a hostile environment for drugs, especially proteins and polypeptides, owing to acid hydrolysis. Local delivery in an oral cavity has particular applications in the treatment of toothaches, periodontal disease, and bacterial infections. Poly(acrylic acid) (PAA)-based hydrogels prepared using a chemical initiator have been attempted for a mucoadhesive system owing to their flexibility and excellent bioadhesion. In this experiment, PAA and polyethylene glycol (PEG) were selected to prepare using a radiation process a bioadhesive hydrogel for adhesion to mucosal surfaces. PAA and PEG were dissolved in purified water to prepare a homogeneous PAA/PEG solution, and the solution was then irradiated using an electron beam at dose up to 70 kGy to make the hydrogels. Their physical properties, such as gel percent, swelling percent, and adhesive strength to mucosal surfaces, were investigated. In this experiment, various amounts of PEG were incorporated into the PAA to enhance the mucoadhesive property of the hydrogels. The effect of the molecular weight of PEG on the mucoadhesion was also examined.

  6. Poly(acrylic acid)/polyethylene glycol hygrogel prepared by using gamma-ray irradiation for mucosa adhesion

    Science.gov (United States)

    Nho, Young-Chang; Park, Jong-Seok; Shin, Jung-Woong; Lim, Youn-Mook; Jeong, Sung-In; Shin, Young-Min; Gwon, Hui-Jeong; Khil, Myung-Seob; Lee, Deok-Won; Ahn, Sung-Jun

    2015-01-01

    A buccal delivery system provides a much milder environment for drug delivery compared to an oral delivery which presents a hostile environment for drugs, especially proteins and polypeptides, owing to acid hydrolysis. Local delivery in an oral cavity has particular applications in the treatment of toothaches, periodontal disease, and bacterial infections. Poly(acrylic acid) (PAA)-based hydrogels prepared using a chemical initiator have been attempted for a mucoadhesive system owing to their flexibility and excellent bioadhesion. In this experiment, PAA and polyethylene glycol (PEG) were selected to prepare using a radiation process a bioadhesive hydrogel for adhesion to mucosal surfaces. PAA and PEG were dissolved in purified water to prepare a homogeneous PAA/PEG solution, and the solution was then irradiated using an electron beam at dose up to 70 kGy to make the hydrogels. Their physical properties, such as gel percent, swelling percent, and adhesive strength to mucosal surfaces, were investigated. In this experiment, various amounts of PEG were incorporated into the PAA to enhance the mucoadhesive property of the hydrogels. The effect of the molecular weight of PEG on the mucoadhesion was also examined.

  7. Fission prompt gamma-ray multiplicity distribution measurements and simulations at DANCE

    Energy Technology Data Exchange (ETDEWEB)

    Chyzh, A; Wu, C Y; Ullmann, J; Jandel, M; Bredeweg, T; Couture, A; Norman, E

    2010-08-24

    The nearly energy independence of the DANCE efficiency and multiplicity response to {gamma} rays makes it possible to measure the prompt {gamma}-ray multiplicity distribution in fission. We demonstrate this unique capability of DANCE through the comparison of {gamma}-ray energy and multiplicity distribution between the measurement and numerical simulation for three radioactive sources {sup 22}Na, {sup 60}Co, and {sup 88}Y. The prospect for measuring the {gamma}-ray multiplicity distribution for both spontaneous and neutron-induced fission is discussed.

  8. Gamma-Ray Localization of Terrestrial Gamma-Ray Flashes

    CERN Document Server

    Marisaldi, M; Trois, A; Giuliani, A; Tavani, M; Labanti, C; Fuschino, F; Bulgarelli, A; Longo, F; Barbiellini, G; Del Monte, E; Moretti, E; Trifoglio, M; Costa, E; Caraveo, P; Cattaneo, P W; Chen, A; D'Ammando, F; De Paris, G; Di Cocco, G; Di Persio, G; Donnarumma, I; Evangelista, Y; Feroci, M; Ferrari, A; Fiorini, M; Froysland, T; Galli, M; Gianotti, F; Lapshov, I; Lazzarotto, F; Lipari, P; Mereghetti, S; Morselli, A; Pacciani, L; Pellizzoni, A; Perotti, F; Picozza, P; Piano, G; Pilia, M; Prest, M; Pucella, G; Rapisarda, M; Rappoldi, A; Rubini, A; Sabatini, S; Soffitta, P; Striani, E; Vallazza, E; Vercellone, S; Vittorini, V; Zambra, A; Zanello, D; Antonelli, L A; Colafrancesco, S; Cutini, S; Giommi, P; Lucarelli, F; Pittori, C; Santolamazza, P; Verrecchia, F; Salotti, L; 10.1103/PhysRevLett.105.128501

    2010-01-01

    Terrestrial Gamma-Ray Flashes (TGFs) are very short bursts of high energy photons and electrons originating in Earth's atmosphere. We present here a localization study of TGFs carried out at gamma-ray energies above 20 MeV based on an innovative event selection method. We use the AGILE satellite Silicon Tracker data that for the first time have been correlated with TGFs detected by the AGILE Mini-Calorimeter. We detect 8 TGFs with gamma-ray photons of energies above 20 MeV localized by the AGILE gamma-ray imager with an accuracy of 5-10 degrees at 50 MeV. Remarkably, all TGF-associated gamma rays are compatible with a terrestrial production site closer to the sub-satellite point than 400 km. Considering that our gamma rays reach the AGILE satellite at 540 km altitude with limited scattering or attenuation, our measurements provide the first precise direct localization of TGFs from space.

  9. Combined effects of {gamma}-rays and acidification on an experimental model ecosystem

    Energy Technology Data Exchange (ETDEWEB)

    Fuma, Shoichi; Ishii, Nobuyoshi; Takeda, Hiroshi [National Inst. of Radiological Sciences, Chiba (Japan); Kawabata, Zen' ichiro [Kyoto Univ. (Japan). Center for Ecological Research; Ichimasa, Yusuke [Ibaraki Univ., Mito (Japan). Faculty of Science

    2002-05-01

    It is necessary to evaluate combined effects of ionizing radiation and other toxic agents on ecosystems, because ecosystems are exposed to these various factors. The authors studied combined effects of {gamma}-rays and acidification on an experimental model ecosystem (microcosm) mimicking aquatic microbial communities. Microcosms, consisted of flagellate algae Euglena gracilis Z as a producer, ciliate protozoa Tetrahymena thermophila B as a consumer and bacteria Escherichia coli DH5{alpha} as a decomposer, were loaded by the following treatments: Irradiation with 100 Gy {sup 60}Co {gamma}-rays; Acidification of culture medium to pH4.0 with the mixture of 0.1 N HNO{sub 3} and 0.1 N H{sub 2}SO{sub 4} (1:1, v/v), which mimicked acid rain; and Irradiation with 100 Gy {gamma}-rays followed by the acidification of the culture medium (pH 4.0). The {gamma}-irradiation induced a temporary decrease in cell densities of E. coli, but did not affect cell densities of the other species. The concentrations of chlorophyll a and ATP in the microcosm were not affected by the {gamma}-irradiation, and chlorophyll a concentrations in a Eu. gracilis cell were not affected, either. The acidification significantly decreased cell densities of T. thermophila, slightly decreased cell densities of E. coli, and slightly increased cell densities of Eu. gracilis. The concentrations of chlorophyll a and ATP in the microcosm were increased by the acidification, although chlorophyll a concentrations in a Eu. gracilis cell were decreased. The combined exposure to {gamma}-rays and acids temporarily decreased cell densities of E. coli, significantly decreased cell densities of T. thermophila, and slightly increased cell densities of Eu. gracilis. The concentrations of chlorophyll a and ATP in the microcosm were increased by the combined exposure, although chlorophyll a concentrations in a Eu. gracilis cell were decreased. The authors therefore conclude that combined exposure to {gamma}-rays and acids

  10. A Green Platform for Preparation of the Well-Defined Polyacrylonitrile: 60Co γ-ray Irradiation-Initiated RAFT Polymerization at Room Temperature

    Directory of Open Access Journals (Sweden)

    Shuangshuang Zhang

    2017-01-01

    Full Text Available 60Co γ-ray irradiation-initiated reversible addition–fragmentation chain transfer (RAFT polymerization at room temperature with 2-cyanoprop-2-yl 1-dithionaphthalate (CPDN as the chain transfer agent was first applied to acrylonitrile (AN polymerization, providing a “green” platform for preparing polyacrylonitrile (PAN-based carbon fibers using an environment-friendly energy source. Various effects of dose rate, molar ratio of the monomer to the chain transfer agent, monomer concentration and reaction time on the AN polymerization behaviors were performed to improve the controllability of molecular the weight and molecular weight distribution of the obtained PAN. The feature of the controlled polymerization was proven by the first-order kinetics, linear increase of the molecular weight with the monomer conversion and a successful chain-extension experiment. The molecular weight and molecular weight distribution of PAN were characterized by size exclusion chromatography (SEC. 1H NMR and Matrix assisted laser desorption ionization/time of flight mass spectra (MALDI-TOF-MS confirmed the chain-end functionality of PAN, which also was supported by the successful chain-extension experiments of original PANs with acrylonitrile and styrene as the second monomers respectively.

  11. Gamma-ray Explosion in Multiple Compton Scattering Regime

    CERN Document Server

    Gong, Z; Shou, Y R; Qiao, B; Bulanov, S V; Esirkepov, T Zh; Bulanov, S S; Chen, C E; He, X T; Yan, X Q

    2016-01-01

    Gamma-ray explosion from near critical density (NCD) target irradiated by four symmetrical imploding laser pulses is numerically investigated. With peak intensities about $10^{23}$ W/cm$^2$, the laser pulses boost electron energy through direct laser acceleration, while pushing them inward with the ponderomotive force. After backscattering with counter-propagating laser, the accelerated electron will be trapped in the optical lattice or the electromagnetic standing waves (SW) created by the coherent overlapping of the laser pulses, and meanwhile emit gamma-ray photon in Multiple Compton Scattering regime, where electron acts as a medium to transfer energy from laser to gamma-ray. The energy conversion rate from laser pulses to gamma-ray can be as high as around 50\\%. It may become one of the most efficient gamma-ray sources in laboratory.

  12. Living/controlled free radical copolymerization of chlorotrifluoroethene and butyl vinyl ether under 60Co γ-ray irradiation in the presence of S-benzyl O-ethyl dithiocarbonate.

    Science.gov (United States)

    Liu, Lei; Lu, Dan; Wang, Hu; Dong, Qibao; Wang, Pucheng; Bai, Ruke

    2011-07-21

    Living/controlled free radical copolymerization of chlorotrifluoroethene and butyl vinyl ether has been successfully achieved at room temperature under (60)Co γ-ray irradiation in the presence of S-benzyl O-ethyl dithiocarbonate. The alternating and block copolymers have been obtained with well-defined molecular weights and narrow molecular weight distributions.

  13. 大剂量rhG-CSF早期单次给药对60Coγ射线照射小鼠的治疗作用%Therapeutic effects of early administration of a single high dose of rhG-CSF on mice irradiated by 60Coγ rays

    Institute of Scientific and Technical Information of China (English)

    韩阿如娜; 余祖胤; 柳晓兰; 从玉文

    2011-01-01

    Objective To observe the therapeutic effects of early administration with a single high dose of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on mice irradiated with 60Co γ rays, and provide a reference for the treatment of acute radiation syndrome (ARS) by using cytokines. Methods Male C57 mice underwent a total body irradiation of 8. Ogy 60Co y ray, and they were treated with rhG-CSF, at 0.5h and 24h, subcutaneously in a dose of 2, 1 and 0. 5mg/kg, respectively. The 30-day survival rate and mean survival time were observed in the lethal irradiated mice. The peripheral blood cell counts and bone marrow nucleated cell counts were evaluated in the sublethally irradiated mice. Results Early administration of a high dose of rhG-CSF significantly increased 30-day survival rate and prolonged mean survival time of mice with lethal irradiation dose. A single injection of rhG-CSF (lmg/kg) at 0. 5h after irradiation was an optimal administration schedule. In addition, early administration with a single high dose of rhG-CSF improved the recovery of bone marrow nucleated cell counts and peripheral blood counts, including white blood cell (WBC), red blood cell (RBC) and platelet in mice exposed to 6. Ogy irradiation. Conclusion Early administration of a single high dose rhG-CSF may have a favorable therapeutic effect on mice irradiated with 60Co y ray.%目的 观察大剂量rhG-CSF早期单次给药对60Coγ射线照射小鼠的治疗作用,为细胞因子治疗急性放射病提供实验依据.方法 雄性C57小鼠,经8.0Gy 60Co γ射线全身照射后于0.5、24h各皮下注射一次不同剂量rhG-CSF(2、1mg/kg和0.5mg/kg),观察致死剂量照射小鼠的30d存活率及平均生存时间.小鼠经6.0Gy 60Co γ射线全身照射后,通过不同给药方案及不同剂量rhG-CSF早期干预,观察亚致死剂量照射小鼠的外周血象和骨髓有核细胞数的变化.结果 大剂量rhG-CSF早期干预明显提高致死剂量照射小鼠的30d存

  14. Characterization of {sup 60}Co and {sup 137}Cs beams from irradiator Shepherd 81 - 14D of LNMRI/IRD in radiation protection; Caracterizacao dos feixes de {sup 60}Co and {sup 137}Cs do Irradiador Shepherd 81 - 14D do LNMRI/IRD em radioprotecao

    Energy Technology Data Exchange (ETDEWEB)

    Silva, C.N.M. da; Cabral, T.S., E-mail: cosme@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2015-07-01

    The objective of this work is the characterization of {sup 60}Co beams and the {sup 137}Cs irradiator Shepherd 81-14D acquired by the National Metrology Laboratory of Ionising Radiation of the Institute of Radiation Protection and Dosimetry (LNMRI /IRD), for use in calibration of measuring instruments of gamma radiation in air kerma and ambient dose equivalent, irradiation of films and TLD's. Field homogeneity measurements were carried out, calculated input and output time of the source and commissioning of sources. (author)

  15. Cytotoxicity evaluation of Diethyltoluamide (DEET) in Perna perna (Linnaeus, 1758) mussels non-irradiated and irradiated with {sup 60}Co gamma radiation; Avaliacao da citotoxicidade do dietiltoluamida (DEET) em mexilhoes Perna perna (Linnaeus, 1758) irradiados e nao irradiados com radiacao gama de {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Martini, Gisela de Assis

    2013-07-01

    Recent studies have identified the presence of several emerging pollutants in aquatic environments. The occurrence in different environmental matrices has been continuously reported, highlighting the need for toxicity studies. The DEET (N,N-diethyl-meta-toluamide) is the active ingredient used in most insect repellents, and is present in many commercially available formulations. Apart from chemical pollutants, aquatic organisms are subject to exposure of ionizing radiation from natural sources or in the vicinity of nuclear power plants. The present study evaluated the toxicity of DEET in organisms irradiated and non-irradiated with {sup 60}Co gamma radiation, and the effects that radiation causes in lysosomes of hemocytes of Perna perna mussel. For this purpose, assays were performed to identify the acute toxicity of DEET concentration and the dose of gamma radiation able to cause mortality. Subsequently, cytotoxicity assays were carried out to assess the stability of the lysosomal membrane in organisms exposed to ionizing radiation and DEET. According to the results obtained in acute toxicity tests, the concentration of DEET that causes mortality of 50% exposed organisms (LC50) is 114,27 mg L{sup -1}, and the radiation dose that causes mortality (LD50) is 1068 Gy. In the cytotoxicity assays, the concentration of the non-observed effect (NOEC) for irradiated and non-irradiated organisms 0.0001 mg L-1 and observed effect concentration (LOEC) at concentrations above this. The IC25 (72h) for non-irradiated organisms was 0.0003 mg L-1 and IC50 (72h) was 0.0008 mg L{sup -1} for irradiated and non-irradiated organisms. Despite of the concentrations of effect found in this study were higher than in the environment, both measurements are in the same order of magnitude and should be also take into account the possible synergistic effects of DEET with other contaminants in the aquatic environment. (author)

  16. Effect of sodium alginate coating and 60Coirradiation treatment on fresh-keeping of golden silk jujube%海藻酸钠涂膜及60Co-γ辐照处理对小枣的保鲜作用

    Institute of Scientific and Technical Information of China (English)

    杨伟; 徐莹; 樊燕; 汪东风; 孙寿魁

    2012-01-01

    Using golden silk jujube at full-red storage as materials,the effects of different preservation treatments(60Coirradiation,coating with sodium alginate,and 60Co-γ irradiation+coating with sodium alginate,respectively) on the post-harvest fruit quality during cold storage were investigated,and the weight loss rate,total sugar content,reducing sugar content,VC content,and ratio of sugar to acid were determined.The results indicated that 60Coirradiation,coating with sodium alginate and 60Co-γ irradiation+coating with sodium alginate all had an obvious fresh-keeping effect.The result showed that the three treatments reduced water loss,delayed the decrease of VC and titratable acid content,and the increase of sugar to acid ratio,and 60Co-γ irradiation+coating with sodium alginate maintained a relatively high content of total sugar and reducing sugar.Especially,the preservative effect of the 60Co-γ irradiation+coating with sodium alginate treatment was obviously superior to the control group,60Coirradiation or coating with sodium alginate alone,which could obviously improve the quality of post-harvest cold storage of golden silk jujube.%以全红期的山东省乐陵小枣为实验材料,分别进行60Co-γ辐照处理、海藻酸钠涂膜处理及二者结合处理后,与对照组同时于(2±0.5)℃冷库贮藏,并对低温贮藏过程中枣的失重率、总糖、还原糖、VC、可滴定酸含量及糖酸比的变化进行测定。结果表明:涂膜、辐照、涂膜+辐照处理均能有效减少水分散失,延缓VC和可滴定酸的下降,抑制糖酸比的上升,涂膜+辐照处理能保持较高的总糖、还原糖含量。其中,60Co-γ辐照+海藻酸钠涂膜处理于(2±0.5)℃冷库贮藏保鲜效果显著优于其他实验处理组,有助于提高乐陵小枣采后的低温贮藏品质。

  17. Effects of low dose rate 60Co γ ray combined with 252Cf neutron irradiation on hematopoietic and antioxidation systems in rats%低剂量率60Co γ射线和252Cf裂变中子混合照射对大鼠造血及抗氧化系统的影响

    Institute of Scientific and Technical Information of China (English)

    莫琳芳; 何颖; 侯登勇; 钱甜甜; 蒋定文; 王岩; 刘玉明; 李珂娴; 王庆蓉

    2013-01-01

    Objective To study the effects of low dose rate 60Co γ ray combined with 252Cf neutron irradiation on hematopoietic and antioxidation systems in rats.Methods Sixteen SD male rats were randomly divided into the irradiation group and the control group,each consisting of 8 rats.The irradiation group was exposed to whole-body 60 Co γray (with daily dose rate of 0.072 Gy) for 1 hour and to 252 Cf neutron (with daily dose rate of 0.085 mGy/h) for 20 hours,for a total of 7 successive days.Peripheral blood cell counts,main organ indices,bone marrow DNA contents,SOD activity and MDA content of rats were monitored,at day 8 after irradiation.Results Compared with those of the control group [(6.2 ± 2.4) × 109/L],WBC of the irradiation group decreased significantly following irradiation [(3.4 ± 1.2) × 109/L],(P < O.05),but no statistical significance could be noted in the changes of various organ indices (P > O.05).Bone marrow DNA contents and serum SOD activity all decreased significantly (P < 0.05),while organ indices and MDA contents seemed to increase,but without statistical significance (P > 0.05).Conclusions 60 Co γirradiation combined with 252Cf neutron irradiation could obviously damage the hemopoietic and anti-oxidation systems of rats.%目的 探讨低剂量率60Co γ射线与252Cf裂变中子混合照射对大鼠的生物效应.方法 16只雄性SD大鼠按数字表法随机分成实验组和对照组,每组8只.实验组每天依次暴露于60Co γ射线1h(剂量率为0.072 Gy/h),252Cf裂变中子20 h(剂量率为0.085 mGy/h),连续7d.照后第8天检测大鼠外周血细胞计数、主要脏器指数、骨髓DNA含量、血清超氧化物歧化酶(SOD)活力及丙二醛(MDA)含量.结果 与对照组[(6.2 ±2.4)×109/L]相比,实验组大鼠外周血白细胞数[(3.4±1.2)×109/L](WBC)显著降低(P<0.05),各项脏器指数变化组间差异无统计学意义(P>0.05),骨髓DNA含量显著降低(P<0.05);血清SOD活力显著降低(P<0

  18. Total integrated dose testing of solid-state scientific CD4011, CD4013, and CD4060 devices by irradiation with CO-60 gamma rays

    Science.gov (United States)

    Dantas, A. R. V.; Gauthier, M. K.; Coss, J. R.

    1985-01-01

    The total integrated dose response of three CMOS devices manufactured by Solid State Scientific has been measured using CO-60 gamma rays. Key parameter measurements were made and compared for each device type. The data show that the CD4011, CD4013, and CD4060 produced by this manufacturers should not be used in any environments where radiation levels might exceed 1,000 rad(Si).

  19. The Study of Setting 60CoIrradiation does of Cumin Powder%孜然粉~(60)Co-γ射线辐照杀菌剂量的设定

    Institute of Scientific and Technical Information of China (English)

    李姣; 赵谋明; 吴军

    2009-01-01

    The pollution of cumin powder was investigated,and the impacts of irradiation dose and microbial sensitivity factors were analyzed. Results indicated Gamma irradiation was of the effective sterilization methods on polluted cumin power,particularly on the number of total bacteria and coliforms. The D_(10) value fluctuates at different time points during production,which makes it difficult to set fixed dosage; on the other hand its water activity was not significantly affected under the conditions. Therefore,with the presumption of consistent production condition,the use of control charts to monitor the initial bacteria pollution of spices could rapidly and accurately determine irradiation dose of Cumin powder.%调查了孜然粉污染情况,分析了微生物的辐照敏感性及其影响因素.结果表明,γ射线辐照对细菌总数和大肠菌群数污染严重的孜然粉有明显的杀菌效果.但由于D_(10)值随生产时间波动较大,对剂量设定造成困难,而在所确定的实验条件下,水分活度对其影响差异不显著.为此,笔者在生产状况稳定的前提下,利用控制图监测香辛料初始菌污染情况,从而可以快速确定辐照杀菌剂量.

  20. Airborne gamma-ray spectrometry

    DEFF Research Database (Denmark)

    Hovgaard, Jens

    A new method - Noise Adjusted Singular Value Decomposition, NASVD - for processing gamma-ray spectra has been developed as part of a Ph.D. project. By using this technique one is able to decompose a large set of data - for example from airborne gamma-ray surveys - into a few spectral components. ...

  1. Research on novel crosslinkers of polyolefins using {gamma}-ray

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Dong Hack; Lee, In jai; Yang, Nam Choul; Hwang, Jo Il; Chung, Woo Young [Hanyang University, Seoul (Korea)

    2001-04-01

    The radiation processing has been widely used as the modification technique to develop new materials such as high performance polymers in which the conventional chemical processing has been unable to apply. For the purpose of using in nuclear power plants, cable materials are required to have excellent physical and chemical properties such as high thermal, radiation and chemical stabilities. Conventional crosslinkers for cable materials such as triallyl cyanurate-based amine derivatives show low melting points and high vapor pressures, which causes the large weight loss due to the high working temperature during the procedure of the film preparation. In this research, we synthesized crosslinkers having imide groups to increase thermal and radiation stabilities. The mixture of LDPE and these crosslinkers was irradiated with 60Co {gamma}-rays at room temperature in nitrogen. The absorbed does range from 1-160KGy. The synthesized crosslinkers showed a good compatibility with LDPE. Among these crosslinkers, m-xylylenedimaleimide is the best in gel fraction enhancement. LDPE crosslinked with m-xylylenedimaleimide displays higher tensile strength than that crosslinked with triallyl cyanurate. In case of elongation property, the usage of m-xylylenedimaleimide crosslinker shows the best result than those of commercial crosslinkers such as triallyl cyanurate and trimethylol propane triacrylate. 24 refs., 21 figs., 1 tabs. (Author)

  2. Study on mutation induced effect of gamma ray and DES on black bean phaseolus vulgaris

    Energy Technology Data Exchange (ETDEWEB)

    Le Thi Dinh; Pham Le Ha; Nguyen Van Toan; Le Xuan Tham [Nuclear Research Institute, Radiobiology Department, Dalat (Viet Nam)

    2001-03-01

    The study on mutation induced effect of gamma ray and DES on black bean Phaseolus vulgaris was carried out at Radiobiology Department, Nuclear Research Institute of Dalat. Dry seeds of variety No.1847 - Bonita - Cuba in set of 13 black bean varieties were irradiated with gamma ray from {sup 60}Co source at dose range from 150 Gy to 350 Gy and treated with DES at concentration from 0.1% to 0.3% in 2 hours for experiments in laboratory. The doses of 200, 250, 300 Gy and concentration of 0.2% DES in 2 hours were selected to treat dry seeds for experiments on the field. In populations of M{sub 1} generation, the height, number of branches and fruits per plant, number of seeds per fruit were decreased with increasing of irradiation doses. In populations of M{sub 2} generation, individual variants in leaf shape, chlorophyll, short stem, dwarf, early maturity, flowering in very short time were obtained and selected in all treatment cases. Mutation frequency at dose of 300 Gy was higher than that in other treatment cases, but ratio of sterility is also largest. The mutant lines of early maturity and short stem with flowering in very short time are promised materials for further studies. (author)

  3. 60Co γ照射加深低温保存对大鼠同种带瓣主肺动脉免疫原性的作用%Immunogenicity in rat valved pulmonary homograft conduits with 60Co γ, irradiation and cryopreservation

    Institute of Scientific and Technical Information of China (English)

    刘英宇

    2008-01-01

    Objective The method of keeping valved pulmonary homograft conduits(VPHC) by using 60Co γ irradiation and cryopreservation is used in this experiment and the transplantation model of VPHC is built. Different effects to the immunogenicity in VPHC rat caused by different dosage of 60 Co iracliation are observed. To determine the suitable dosage of 60 Co γ used prior to cryopreservation in order to reduce the immunogenicity yet maintain the viability of VPHC. And to provide academic basis for further basic research and clinical application. Methods Fifty one-month old Wistar rats were used as donors and were divided into five groups (randomly,leave out sex ). Fifty SD adult rats were used as recipients and were divided into five groups respectively. Four experimental groups were irradiated with 60 Co γ of different dosages prior to cryopreservation:300 Gy group, 600 Gy group, 900 Gy group, 1200 Gy group. The experimental control group received cryopreservation only. And ten SD rats underwent right carotid artery end-to-end anastomosis were used as a control group. Flow cytometry was used to test CD4+ ,CD8+ T cells in peripheral blood of recipient rats at weekly interval of 1,2, 3 weeks postoperatively. Results There is significant difference between experimental group and control group in percentages of CD4+ , CD8+ T cells and CD4+/CD8+ ( P<0.05). Conclusions 60 Co γ irradiation can keep the activity of VPHC while reduce immunogenicity of VPHC at the same time in rats.%目的 本实验应用60Co γ射线照射加液氮深低温保存大鼠同种带瓣主肺动脉(valvedpulmonary homograft conduits,VPHC),并建立大鼠VPHC颈总动脉移植模型,观察不同照射剂量对同种带瓣主肺动脉免疫原性的作用,寻找合适照射剂量,为进一步基础研究及临床应用提供理论依据.方法 1月龄封闭群Wistar大鼠50只作为供体鼠,雌雄不拘,随机分为单纯深低温保存组(实验对照组)、300 Gy照射组、600 Gy照射组、900

  4. [Effect of tonicity of the medium on the sensitivity of Escherichia coli bacteria to gamma-quantum 60Co, ultrasound and hyperthermia].

    Science.gov (United States)

    Morozov, I I; Petin, V G; Morozova, G V

    1998-01-01

    The cell lethality and permeability induced in Escherichia coli B/r and Escherichia coli BS-1 by 60Co gamma-ray irradiation, ultrasound and hyperthermia in media containing different concentrations of NaCl have been investigated. It was shown that independently from the nature of damaging factors hypotonic media increase while hypertonic media in certain range of osmolyte concentration decrease sensitivity of cells to action of this factors. It was proposed that discovered phenomenology was caused by salt modification of status of the cell osmotic homeostasis destabilizing by ionizing radiation, ultrasound or hyperthermia and was not related with the system of dark repair of DNA.

  5. 刺五加多糖对60Coγ射线照射大鼠外周血细胞的影响%Protective effect of Acanthopanax Senticosus polysaccharide on peripheral hematological cells in rats irradiated with 60 Co γ ray

    Institute of Scientific and Technical Information of China (English)

    莫琳芳; 李珂娴; 钱甜甜; 沈先荣; 何颖; 蒋定文; 刘玉明; 侯登勇; 刘琼; 陈伟; 王庆蓉

    2012-01-01

    Objective To investigate the protective effect of Acanthopanax Senticosus polysaccharide on peripheral hematological cells in rats irradiated with 60Co γ ray.Methods Sixty-three male rats were randomly divided into 7 groups,i.e.the normal control group,the irradiation control group,the WR-2721 group,the 523 group and the 3 experimental groups with high (200 mg · kg-1 · d-1 ), moderate (100 mg · kg-1 · d-1) and low (50 mg· kg-1 · d-1) doses of Acanthopanax Senticosus polysaccharide.The marrow-depressed model rats received 5 Gy 60Co γ ray whole body irradiation with a dose absorption rate of (0.388 Gy/h) except those in the normal control group.WBC,RBC and PLT in the peripheral blood were detected with hemocytometer both on the 5th day before irradiation and the 3rd and 10th days after exposure.Results When detected on the 3rd day following irradiation,WBC in the peripheral blood of the irradiated animals decreased to a level of (2.482 ±0.808) × 109 · ml-1,RBC to a level of (7.680 ±0.926) × 1012·ml-1 and PLT to a point of (360.000±43.967) × 109 · ml-1,having a rather significant decrease in the indices,when compared with those of the normal control group (P < 0.01 ). On the 10th day following irradiation,WBC in the peripheral blood of the irradiated control animals decreased to a level of (4.764 ±0.679) × 109 · ml - 1,RBC decreased to (9.004 ± 0.761 ) × 1012 · ml -1 and PLT to ( 390.000 ± 43.967 ) ×109 · ml-1,with all the indices decreasing more obviously than those of the normal control group(P < 0.01 ).Data detection before irradiation with 60Co γ ray indicated that WBC,RBC and PLT in the peripheral blood of the experimental animals elevated to various extent,when compared with those of the normal control group.Detection after irradiation showed that Acanthopanax Senticosus polysaccharide could obviously increase the levels of WBC,RBC and PLT in the peripheral blood of the irradiated animals,when compared with those of the irradiation

  6. Applied gamma-ray spectrometry

    CERN Document Server

    Dams, R; Crouthamel, Carl E

    1970-01-01

    Applied Gamma-Ray Spectrometry covers real life application of the gamma-ray and the devices used in their experimental studies. This book is organized into 9 chapters, and starts with discussions of the various decay processes, the possible interaction mechanisms of gamma radiation with matter, and the intrinsic and extrinsic variables, which affect the observed gamma-ray and X-ray spectra. The subsequent chapters deal with the properties and fabrication of scintillation detectors, semiconductor detectors, and proportional gas counters. These chapters present some of the most widely utilized

  7. Biodegradation polyurethane derived from vegetable oil irradiated with gamma rays 25 kGy and 100 kGy; Biodegradacao de poliuretano derivado de oleo vegetal irradiado com raios gama 25 kGy e 100 kGy

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Antonia M. dos, E-mail: amsantos@rc.unesp.br [Universidade Estadual Paulista - Unesp, Rio Claro, SP (Brazil); Claro Neto, Salvador [Universidade de Sao Paulo - USP, Campus de Sao Carlos, SP (Brazil); Azevedo, Elaine C. de [Universidade Federal do Parana, Campus de Curitiba, PR (Brazil)

    2011-07-01

    The environment requires polymers that can be degraded by the action of microorganisms. In this work was studied the biodegradation of polyurethane samples derived from vegetable oil (castor oil), which were irradiated with gamma rays 25 kGy and 100 kGy compared with the same polyurethane without being irradiated. Biodegradation of polyurethane was carried out in culture medium containing the fungus Aspergillus niger by 146 days and the result was evaluated using the technique of thermogravimetric analysis, where there was a change of behavior of the curves TGA / DTG occurred indicating that chemical modifications of molecules present in the structure of the polymer chain, thus confirming that the material has undergone the action of microorganisms. (author)

  8. Gamma-ray-selected AGN

    Science.gov (United States)

    Giommi, Paolo

    2016-08-01

    The gamma-ray band is the most energetic part of the electromagnetic spectrum. As such it is also where selection effects are most severe, as it can only be reached by the most extreme non-thermal AGN. Blazars, with their emission dominated by non-thermal blue-shifted radiation arising in a relativistic jet pointed in the direction of the observer, naturally satisfy this though requirement. For this reason, albeit these sources are intrisically very rare (orders of magnitude less abundant than radio quiet AGN of the same optical magnitude) they almost completely dominate the extragalactic gamma-ray and very high energy sky. I will discuss the emission of different types of blazars and the selection effects that are at play in the gamma-ray band based on recent results from the current generation of gamma-ray astronomy satellites, ground-based Cherenkov telescopes, and Monte Carlo simulations.

  9. Peculiarities of agaricus bisporus (J. Lge) Imbach strains obtained under the. gamma. -ray effect

    Energy Technology Data Exchange (ETDEWEB)

    Stanek, M.; Dudka, Yi.O.; Byis' ko, N.A.; Vasser, S.P.; Srv, A.; Kolesnichenko, L.P.; Yablons' kij, Yi. (Ceskoslovenska Akademie Ved, Novy Hradek. Mikrobiologicky Ustav; AN Ukrainskoj SSR, Kiev. Inst. Botaniki)

    A technique of irradiation of Agaricus bisporus (J.Lge) Imbach strains by gamma-rays is described, characteristics of strains, received during irradiation are given (productivity, protein content). The efficiency of gamma-ray usage in A bisporus selection is considered.

  10. Gamma-ray Pulsar Revolution

    CERN Document Server

    Caraveo, Patrizia A

    2013-01-01

    Isolated Neutron Stars (INSs) were the first sources identified in the field of high-energy gamma-ray astronomy. At first, in the 70s, there were only two identified sources, the Crab and Vela pulsars. However, although few in number, these objects were crucial in establishing the very concept of a gamma-ray source. Moreover, they opened up significant discovery space both in the theoretical and phenomenological fronts. The need to explain the copious gamma-ray emission of these pulsars led to breakthrough developments in understanding the structure and physics of neutron star magnetospheres. In parallel, the 20-year-long chase to understand the nature of Geminga unveiled the existence of a radio-quiet, gamma-ray-emitting, INS, adding a new dimension to the INS family. Today we are living through an extraordinary time of discovery. The current generation of gamma-ray detectors has vastly increased the population of known of gamma-ray-emitting neutron stars. The 100 mark was crossed in 2011 and we are now appr...

  11. An Experimental Study on the Effect of 60Co γ Rays Irradiation on Guinea Pig Cochlear Nucleus%豚鼠耳颞部60Coγ射线照射对耳蜗核影响的实验研究

    Institute of Scientific and Technical Information of China (English)

    钟华林; 唐安洲; 谢利红

    2012-01-01

    目的 探讨60Coγ射线照射对豚鼠耳蜗核神经元的影响.方法 48只豚鼠随机分为对照组(8只)和实验组(40只),实验组豚鼠于右耳颞部做一次性40 Gy 60Coγ射线照射后的1、4、7、14、30 d行听性脑干反应(auditory brainstem response,ABR)测试,然后处死,行耳蜗核石蜡切片HE染色及免疫组织化学染色,观察细胞形态及半胱氨酸天冬氨酸蛋白酶3(Caspase 3).对照组不予 60Coγ射线照射,行ABR测试后行耳蜗核HE染色,方法同实验组.结果 对照组ABR反应阈为29.17±1.95 dB SPL,实验组在接受60Coγ射线照射后1、4、7、14、30 d ABR阈值升高,分别为31.88±2.59、35.00±3.17、35.83±2.04、39.17±2.05、41.67±2.58 dB SPL,照射后4、7、14、30 d ABR反应阈与对照组比较差异有统计学意义(P<0.05);实验组各时间点ABR波I、II、III潜伏期及I-II、II-III、I-III波间期延长,与对照组比较差异有统计学意义(P<0.05).结论 60Coγ射线照射可导致耳蜗核损伤;Caspase3表达上调可能与耳蜗核神经元射线损伤有关.%Objective To study the effects of 60Coyrays irradiation on cochicar nucleus neurons. Methods Forty eight guinea pigs were randomly divided into control group(8 guinea pigs)and experimental group(40 guinea pigs). The experimental group animals were tested with the auditory brainstcm response at 1 , 4, 7, 14 and 30 days after irradiation of 40 Gy ,thcn the guinea pigs were sacrificed. All cochlcar nuclei tissues were made into paraffin sections. Sections were stained with hacmatoxylin and cosin and Caspasc 3 immunohistochemistry for light microscopic examination. Results ABR threshold in the control group was 29. 17 ± 1. 95 dB SPL. In experimental group, ABR thresholds were 31.88 ± 2. 59 dB SPL ,35.00 ± 3. 17dB SPL ,35.83 ± 2. 04 dB SPL, 39. 17 ± 2. 05 dB SPL, 41. 67 ±2. 58 dB SPL after 60Co irradiation 1 , 4, 7,14, 30 days groups,respectively. The differences of ABR threshold were statistically significant

  12. 60 Coγ射线辐射致LyGDI断裂对K562细胞的延迟性凋亡作用%Delayed K562 cell apoptosis promoted by cleaved LyGDI after 60Co γ-rays irradiation

    Institute of Scientific and Technical Information of China (English)

    孙华丽; 段卫明; 邵彦彦; 肖海楠; 周新文

    2010-01-01

    目的 采用不同剂量的60 Coγ射线照射人红白血病细胞系K562,探究鸟苷酸解离抑制因子-2(LyGDI)在细胞延迟性死亡中的作用以及其调控机制.方法 细胞流式仪PI单染检测细胞周期,藻红B染色观察细胞的凋亡,Western blot分析LyGDI和Rac1蛋白的表达,免疫荧光检测Rac1蛋白在细胞内的分布.结果 K562细胞被阻滞在G2/M期的百分率为71.3%,K562细胞早期凋亡率较低,8 Gy60Co γ射线照射后24 h,凋亡率为14%,呈现出延迟性的细胞凋亡;K562细胞在4 Gy的γ射线照射24 h后,可见LyGDI发生断裂,总的Rac1蛋白表达未发生明显变化,但其在细胞内的分布发生改变,Rac1转移至细胞膜上与少量核内分布,Rac1脱离LyGDI而激活.结论 LyGDI具有增加细胞延迟性凋亡的作用,其断裂使Rac1转移至细胞膜上,诱导Rac1的激活,从而促进了细胞的凋亡.%Objective To elucidate the function and regulatory mechanism of LyGDI involved delayed cell death in the human K562 cells and HL-60 cells induced by 60Co γ-rays. Methods Erythrosine B cells staining was used to count the apoptosis rate. PI staining and flow cytometry were applied to check the cell cycle. The expression of LYGDI and Rac1 was resolved by Western blot by using monoclonal antibody of LyGDI and Racl. The distribution of Racl protein in cells was observed with immunofluorescence by using the confocal microscope. Results The K562 cells showed G2/M phase arrest and the percent age was 71.3%. The apoptosis rate was very low at early post-irradiation stage in the K562 cells. The apoptosis rate was 14% in the K562 cells at 24 h post-irradiation with 8 Gy of γ-rays, and delayed cell apoptosis was present. LyGDI was cleaved in the K562 cells irradiated by 4 Gy 60 Co γ-rays after 24 hours post-irradiation. The expression of Racl protein was not altered at all, but the distribution was changed in the irradiated cells while the Racl protein moved to cell membrane and a little in cell

  13. Extragalactic Gamma-Ray Astrophysics

    CERN Document Server

    CERN. Geneva

    2016-01-01

    During the last decades, various classes of radio-loud active galactic nuclei have been established as sources of high-energy radiation extending over a very broad range from soft gamma-rays (photon energies E~MeV) up to very-high-energy gamma-rays (E>100 GeV). These include blazars of different types, as well as young and evolved radio galaxies. The observed gamma-ray emission from such implies efficient particle acceleration processes taking place in highly magnetized and relativistic jets produced by supermassive black holes, processes that have yet to be identified and properly understood. In addition, nearby starforming and starburst galaxies, some of which host radio-quiet Seyfert-type nuclei, have been detected in the gamma-ray range as well. In their cases, the observed gamma-ray emission is due to non-thermal activity in the interstellar medium, possibly including also a contribution from accretion disks and nuclear outflows. Finally, the high-energy emission from clusters of galaxies remains elusive...

  14. Thermal neutron fluence from ultra low-level gamma-ray spectrometry of spoons activated during the JCO criticality accident at Tokai-mura in 1999.

    Science.gov (United States)

    Hult, Mikael; Martínez Canet, María Jose; Johnston, Peter N; Komura, Kazuhisa

    2002-01-01

    During the JCO-accident in Tokai-mura in 1999, the surrounding village was irradiated by an uncontrolled neutron flux. At some locations in that village, the thermal neutron flux was determined retrospectively by measurement of the very low activity of 51Cr and 60Co in stainless-steel spoons using gamma-ray spectrometry in underground laboratories. Activities determined in the HADES underground facility are presented here, together with calibrations performed using a well-defined thermal neutron flux to directly estimate the fluence of thermal neutrons independent of most assumptions. The results show measurable 51Cr in three samples and 60Co in four samples taken from locations at distances of up to 430m from the accident location despite the elapse of 4 half-lives of 51Cr before measurement. Effects of air transport of the samples were considered and shown to be negligible.

  15. Terrestrial gamma-ray flashes

    Energy Technology Data Exchange (ETDEWEB)

    Marisaldi, Martino, E-mail: marisaldi@iasfbo.inaf.it [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy); Fuschino, Fabio; Labanti, Claudio [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy); Tavani, Marco [INAF-IASF Roma, Via Fosso del Cavaliere 100, I-00133 Roma (Italy); Argan, Andrea [INAF, Viale del Parco Mellini 84, 00136 Roma (Italy); Del Monte, Ettore [INAF-IASF Roma, Via Fosso del Cavaliere 100, I-00133 Roma (Italy); Longo, Francesco; Barbiellini, Guido [Dipartimento di Fisica Università di Trieste and INFN Trieste, via A. Valerio 2, I-34127 Trieste (Italy); Giuliani, Andrea [INAF-IASF Milano, Via Bassini 15, I-20133 Milano (Italy); Trois, Alessio [INAF Osservatorio Astronomico di Cagliari, loc. Poggio dei Pini, strada 54, I-09012 Capoterra (Italy); Bulgarelli, Andrea; Gianotti, Fulvio; Trifoglio, Massimo [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy)

    2013-08-21

    Lightning and thunderstorm systems in general have been recently recognized as powerful particle accelerators, capable of producing electrons, positrons, gamma-rays and neutrons with energies as high as several tens of MeV. In fact, these natural systems turn out to be the highest energy and most efficient natural particle accelerators on Earth. Terrestrial Gamma-ray Flashes (TGFs) are millisecond long, very intense bursts of gamma-rays and are one of the most intriguing manifestation of these natural accelerators. Only three currently operative missions are capable of detecting TGFs from space: the RHESSI, Fermi and AGILE satellites. In this paper we review the characteristics of TGFs, including energy spectrum, timing structure, beam geometry and correlation with lightning, and the basic principles of the associated production models. Then we focus on the recent AGILE discoveries concerning the high energy extension of the TGF spectrum up to 100 MeV, which is difficult to reconcile with current theoretical models.

  16. Zeptosecond $\\gamma$-ray pulses

    CERN Document Server

    Klaiber, Michael; Keitel, Christoph H

    2007-01-01

    High-order harmonic generation (HHG) in the relativistic regime is employed to obtain zeptosecond pulses of $\\gamma$-rays. The harmonics are generated from atomic systems in counterpropagating strong attosecond laser pulse trains of linear polarization. In this setup recollisions of the ionized electrons can be achieved in the highly relativistic regime via a reversal of the commonly deteriorating drift and without instability of the electron dynamics such as in a standing laser wave. As a result, coherent attosecond $\\gamma$-rays in the 10 MeV energy range as well as coherent zeptosecond $\\gamma$-ray pulses of MeV photon energy for time-resolved nuclear spectroscopy become feasible.

  17. Effects of 60 Co γIrradiation and EMS Treatment on Survival Rate and Seeding Growth of Pitaya%60Co γ射线辐照和EMS处理对火龙果成活率及幼苗生长的影响

    Institute of Scientific and Technical Information of China (English)

    邓仁菊; 范建新; 蔡永强; 高安辉; 袁启凤

    2011-01-01

    采用不同剂量的60Coγ射线辐照火龙果枝条,结果表明,枝条的成活率随辐照剂量的增加而降低,白肉火龙果枝条的适宜辐照范围为5 446.6~6 060.1 Rad,红肉火龙果枝条的适宜辐照范围为4 444.1~4 981.7 Rad,粉红火龙果枝条的适宜辐照范围为5 069.1~5 601.0 Rad;辐照处理抑制了火龙果幼苗的生长,且辐照剂量越大,对火龙果幼苗的生长抑制作用越明显.采用不同浓度的EMS溶液处理火龙果嫩芽,结果发现,芽的成活率随EMS浓度增加和处理时间延长而逐渐减小,适宜EMS诱变的浓度范围为0.34~0.41 mol/L;随EMS浓度增加和处理时间的延长,火龙果幼苗的高生长也明显受到抑制.%The cutting branches of pitaya (Hylocereus SPP. ) were irradiated by different dose 60Co γ-rays. The results indicated that survival rate of cutting branches decreased with the increase of irradiation dose, and the suitable irradiation dose rang for mutation breeding was 5 446.6 ~6 060.1 Rad of white flesh pitaya,4 444.1 ~4 981.7 Pad of red flesh pitaya, 5 069.1 ~5 601.0 Red of pink flesh pitaya. Irradiation could inhibit the growth of young seedlings, and for the higher irradiation dose, the inhibition was more significant. The shoots of pitaya were treated with different EMS concentration. The results showed that survival rate of shoot decreased with EMS concentration increased and treatment time prolonged. The suitable EMS concentration rang for mutation breeding was 0.34 ~ 0.41 mol/L, and the higher EMS concentration and longer treatment time had obvious inhibition for height growth of pitaya seedlings.

  18. The Gamma-ray Sky with Fermi

    Science.gov (United States)

    Thompson, David

    2012-01-01

    Gamma rays reveal extreme, nonthermal conditions in the Universe. The Fermi Gamma-ray Space Telescope has been exploring the gamma-ray sky for more than four years, enabling a search for powerful transients like gamma-ray bursts, novae, solar flares, and flaring active galactic nuclei, as well as long-term studies including pulsars, binary systems, supernova remnants, and searches for predicted sources of gamma rays such as dark matter annihilation. Some results include a stringent limit on Lorentz invariance derived from a gamma-ray burst, unexpected gamma-ray variability from the Crab Nebula, a huge gamma-ray structure associated with the center of our galaxy, surprising behavior from some gamma-ray binary systems, and a possible constraint on some WIMP models for dark matter.

  19. Gamma-ray Imaging Methods

    Energy Technology Data Exchange (ETDEWEB)

    Vetter, K; Mihailescu, L; Nelson, K; Valentine, J; Wright, D

    2006-10-05

    In this document we discuss specific implementations for gamma-ray imaging instruments including the principle of operation and describe systems which have been built and demonstrated as well as systems currently under development. There are several fundamentally different technologies each with specific operational requirements and performance trade offs. We provide an overview of the different gamma-ray imaging techniques and briefly discuss challenges and limitations associated with each modality (in the appendix we give detailed descriptions of specific implementations for many of these technologies). In Section 3 we summarize the performance and operational aspects in tabular form as an aid for comparing technologies and mapping technologies to potential applications.

  20. Gamma-ray burst spectra

    Science.gov (United States)

    Teegarden, B. J.

    1982-01-01

    A review of recent results in gamma-ray burst spectroscopy is given. Particular attention is paid to the recent discovery of emission and absorption features in the burst spectra. These lines represent the strongest evidence to date that gamma-ray bursts originate on or near neutron stars. Line parameters give information on the temperature, magnetic field and possibly the gravitational potential of the neutron star. The behavior of the continuum spectrum is also discussed. A remarkably good fit to nearly all bursts is obtained with a thermal-bremsstrahlung-like continuum. Significant evolution is observed of both the continuum and line features within most events.

  1. Photoelectrocatalytic degradation of ethylene with TiO2 modified by 60Coγ-ray irradiation%利用60Co-γ射线辐照使TiO2改性后对乙烯的催化降解效果

    Institute of Scientific and Technical Information of China (English)

    郑森鸿; 叶盛英; 黄迅; 沈生文

    2013-01-01

    Horticultural products are abundant in China. However, a large amount of them were deteriorated due to the lack of appropriate storage and transport technology, resulting in a huge waste. Ethylene gas is one of the main reasons which cause the deterioration of horticultural products in storage. Nanometer TiO2 photoelectrocatalysis technology is a new technique developed in recently. TiO2, under UV light, can degrade organics such as ethylene, so it provides a potentially effective method for keeping free products. However, in practical applications, the mutual composite happens easily, which shorts the lives of the carriers and limits the application of TiO2. The only solution for this problem is to decrease the compositing rate of photoinduced electrons and the holes by modifying the nanometer-sized TiO2. Developing modified method is also a hot topic of researchers here in China and abroad. 60Co-γ ray irradiation reduction technique can modify TiO2 and make it more activity for the catalytic degradation of organics. In order to investigate the effect of TiO2, irradiated by 60Co-γray and loaded with activated carbon fibers (ACF), on photoelectrocatalytic degradation of ethylene in the environment of cold storage, the TiO2/ACF photoelecrorcatalysis materials was deposited with nano-Ag (Ag-TiO2/ACF) and irradiated by 60Co-γray. The effects of 60Co-γray irradiation modified TiO2 (10, 15, 20, 25, 30, 40 kGy) on the photoelectrocatalytic degradation rate of ethylene were investigated in a simulated cold storage environment for horticultural product. X-ray diffractometer and X-ray photoelectron spectroscopy were used to characterize the prepared TiO2. Results from X-ray diffraction showed that: the crystal size has reduced. The percent of anatase decreased from 84.97%in pure TiO2 to 82. 98%in TiO2 treated with a 40 kGy irradiation dose. Result of X-ray photoelectron spectroscopy indicated that the amount of Ti3+, hydroxyl oxygen which have better catalytic activity

  2. Preliminary research on the establishment of non-invasive model of radiation-induced oral mucositis in rats by 60 Coγ-rays irradiation%60 Coγ射线照射大鼠建立放射性口腔黏膜炎模型的初步研究

    Institute of Scientific and Technical Information of China (English)

    刘礼; 陶人川; 雍翔智; 蒋兰岚; 曾启新

    2016-01-01

    目的:建立大鼠放射性口腔黏膜炎模型,观察并分析黏膜组织炎症变化过程。方法:选择SD大鼠45只,随机分为9组:空白对照组;实验组8组均用60 Coγ射线以35 Gy剂量单次照射口鼻部。观察大鼠口腔黏膜状况,对炎症期间拒食的大鼠进行灌注流食喂养。分别于放射后1、3、5、7、10、14、21及28 d处死1组实验组大鼠,对照组于28 d处死,取口腔黏膜组织进行HE染色和光镜下观察。结果:放射后5~6 d,大鼠口腔黏膜出现红肿伴有小面积溃疡;7~8 d小溃疡逐渐融合成大面积溃疡,并持续到9~13 d;14 d开始,溃疡逐渐缩小并愈合;21~28 d溃疡完全愈合。 HE染色显示放射后第5 d,黏膜下层出现大量炎性细胞浸润,但上皮层连续完整;第7、10 d,上皮层崩解、脱落;第14 d溃疡底部可见新生肉芽组织及新生毛细血管;第21、28 d,溃疡处有新的上皮组织出现,基底层排列紧密。结论:经60 Coγ射线照射成功建立放射性口腔黏膜炎大鼠模型,炎症从5~8 d开始,第9~13 d达到高峰,14 d左右开始缓解恢复,21~28 d恢复正常。%Objective:To establish a non-invasive model of radiation-induced oral mucositis( RTOM) in rats and ob-serve the dynamic process of the occurrence,development and healing of mucosal inflammation. Methods:After randomly di-viding 45 SD rats into 9 groups,one group was maintained as a blank control group,while each rat of the other 8 groups re-ceived an irradiation of single 35 Gy dose of 60 Coγ-rays. The condition of the oral mucosal was observed everyday. Each group of experimental rats was sacrificed at the 1 st , 3 rd , 5 th , 7 th , 10 th , 14 th , 21 st and 28 th day after the irradiation respectively. However,the control group of rats were sacrificed only on the 28th day. Oral mucosa tissues of the dead rats were harvested. The samples underwent HE staining for histological

  3. Study of stability of humic acids from soil and peat irradiated by gamma rays; Estudo da estabilidade de acidos humicos extraidos de solo e turfa, frente a radiacao ionizante gama

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Wilson Tadeu Lopes da

    1995-07-01

    Humic acids samples (one deriving from a sedimentary soil and other from a peat), in aqueous media, were irradiated with gamma rays, in doses of 10, 50 and 100 kGy, in order to understand their chemical behavior after the irradiation. The material, before and after irradiation, was analyzed by Elemental Analysis, Functional Groups (carboxylic acids and phenols), UV/Vis Spectroscopy (E{sub 4}/E{sub 6} ratio), IR spectroscopy, CO{sub 2} content and Gel permeation Chromatography (GPC) ). The Elemental Analysis showed the humic acid derived from a peat had a most percentage quantity of Carbon and Hydrogen than the material from a sedimentary soil. From the UV/Vis Spectroscopy, it was observed a decrease of E{sub 4}/E{sub 6} ratio with an increase of the applied dose. The data from GPC are in agreement with this. The results showed that the molecular weight of the material increased by exposing it to a larger radiolitical dose. The peat material was less affected by the gamma radiation than the soil material. The carboxylic groups were responsible by radiochemical behavior of the material. (author)

  4. Relative biological effectiveness of fission neutrons for producing micronuclei in the root-tip cells of onion seedlings after irradiation as dry seeds

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, W.; Ishikawa, Masayori; Hoshi, Masaharu [Hiroshima Univ. (Japan). Research Inst. for Radiation Biology and Medicine; Endo, Satoru [Hiroshima Univ., Higashi-Hiroshima (Japan). Graduate School of Engineering; Ikeda, Hideo [Hiroshima Univ., Higashi-Hiroshima (Japan). Faculty of Education

    2002-12-01

    The relative biological effectiveness (RBE) of mixed neutron and gamma-ray radiation emitted at a {sup 252}Cf source at the Research Institute for Radiation Biology and Medicine, Hiroshima University, compared with {sup 60}Co gamma-ray radiation was determined. The tissue-absorbed dose contribution of the accompanying gamma radiation was about 35.7% to the total tissue-absorbed dose from the {sup 252}Cf mixed radiation. The {sup 252}Cf mixed radiation and {sup 60}Co gamma rays produced approximate linear changes in the frequency of micronuclei induced in root-tip cells of Allium cepa L. onion seedlings after irradiation as dry dormant seeds with varying absorbed doses in onion seeds. Therefore, the RBE for radiation-induced micronuclei was calculated as the ratio of the slopes for the {sup 252}Cf mixed radiation and the {sup 60}Co gamma rays. The deduced RBE value of {sup 252}Cf mixed radiation of {sup 60}Co gamma rays to induce micronuclei in dry dormant onion seed cells was about 90.5{+-}3.6 ({+-}1{sigma}); the RBE of neutrons from the {sup 252}Cf mixed radiation was about 150{+-}6 ({+-}1{sigma}). Furthermore, the sensitivity ratio of the induction rate of micronuclei in dry dormant seeds to that in seedlings by neutrons from {sup 252}Cf mixed radiation was significantly different from that by {sup 60}Co gamma rays. From these results, we concluded that the repair efficiency of DNA damage induced by neutrons may be different from that by gamma rays. (author)

  5. Neutron interrogation system using high gamma ray signature to detect contraband special nuclear materials in cargo

    Science.gov (United States)

    Slaughter, Dennis R.; Pohl, Bertram A.; Dougan, Arden D.; Bernstein, Adam; Prussin, Stanley G.; Norman, Eric B.

    2008-04-15

    A system for inspecting cargo for the presence of special nuclear material. The cargo is irradiated with neutrons. The neutrons produce fission products in the special nuclear material which generate gamma rays. The gamma rays are detecting indicating the presence of the special nuclear material.

  6. Novae in gamma-rays

    CERN Document Server

    Hernanz, M

    2013-01-01

    Classical novae produce radioactive nuclei which are emitters of gamma-rays in the MeV range. Some examples are the lines at 478 and 1275 keV (from 7Be and 22Na) and the positron-electron annihilation emission (511 keV line and a continuum below this energy, with a cut-off at 20-30 keV). The analysis of gamma-ray spectra and light curves is a potential unique and powerful tool both to trace the corresponding isotopes and to give insights on the properties of the expanding envelope determining its transparency. Another possible origin of gamma-rays is the acceleration of particles up to very high energies, so that either neutral pions or inverse Compton processes produce gamma-rays of energies larger than 100 MeV. MeV photons during nova explosions have not been detected yet, although several attempts have been made in the last decades; on the other hand, GeV photons from novae have been detected in some particular novae, in symbiotic binaries, where the companion is a red giant with a wind, instead of a main ...

  7. Short duration gamma ray bursts

    Indian Academy of Sciences (India)

    Patrick Das Gupta

    2004-10-01

    After a short review of gamma ray bursts (GRBs), we discuss the physical implications of strong statistical correlations seen among some of the parameters of short duration bursts (90 < 2 s). Finally, we conclude with a brief sketch of a new unified model for long and short GRBs.

  8. Measurements of high-energy {gamma}-rays with LaBr{sub 3}:Ce detectors

    Energy Technology Data Exchange (ETDEWEB)

    Ciemala, M. [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland)], E-mail: Michal.Ciemala@ifj.edu.pl; Balabanski, D. [INRNE, Bulgarian Academy of Sciences, BG-1784 Sofia (Bulgaria); Csatlos, M. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary); Daugas, J.M. [CEA, DAM, DIF, F-91297 Arpajon Cedex (France); Georgiev, G. [Centre de Spectrometrie Nucleaire et de Spectrometrie de Masse (CSNSM), IN2P3-CNRS and Universite Paris-Sud, Bat 104-108, F-91405 Orsay Cedex (France); Gulyas, J. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary); Kmiecik, M. [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Krasznahorkay, A. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary); Lalkovski, S. [Faculty of Physics, University of Sofia, BG-1164 (Bulgaria); Lefebvre-Schuhl, A. [Centre de Spectrometrie Nucleaire et de Spectrometrie de Masse (CSNSM), IN2P3-CNRS and Universite Paris-Sud, Bat 104-108, F-91405 Orsay Cedex (France); Lozeva, R. [Instituut voor Kernen Stralingsfysica (IKS), Katholieke Universiteit Leuven, B-3001 Leuven (Belgium); Maj, A. [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Vitez, A. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary)

    2009-09-01

    The full-energy peak efficiency calibration and the energy resolution measurements of the 2in.x2in.LaBr{sub 3}{gamma}-ray detector are presented for {gamma}-ray energies in the 700 keV-17.6 MeV range. Measurements were done using a combination of proton-capture nuclear reactions on {sup 27}Al, {sup 23}Na, {sup 39}K, {sup 7}Li and {sup 11}B for high-energy {gamma}-rays, and radioactive sources such as {sup 60}Co and {sup 152}Eu for the lowest energies. At high energies, two {gamma}-rays in a cascade from proton resonance capture were employed using Al, Na{sub 2}WO{sub 4}, K{sub 2}SO{sub 4} and LiBO{sub 2} targets. The obtained results were compared to the simulations performed using a GEANT4 code.

  9. Specification of High Activity Gamma-Ray Sources.

    Science.gov (United States)

    International Commission on Radiation Units and Measurements, Washington, DC.

    The report is concerned with making recommendations for the specifications of gamma ray sources, which relate to the quantity of radioactive material and the radiation emitted. Primary consideration is given to sources in teletherapy and to a lesser extent those used in industrial radiography and in irradiation units used in industry and research.…

  10. Influence of natural antioxidants on lipid composition of beef burgers submitted to irradiation in {sup 60} Co source and electron beams; Influencia de antioxidantes naturais sobre o perfil lipidico de hamburgueres bovinos submetidos a irradiacao por {sup 60}Co e aceleradores de eletrons

    Energy Technology Data Exchange (ETDEWEB)

    Trindade, Reginaldo Almeida da

    2007-07-01

    Radiation processing has been employed in some countries as a mean of treatment to assure microbiological safety of meat and meat products, avoiding the occurrence of food-borne disease. The ionizing radiation may cause some undesirable changes on chemistry composition of food and the lipid oxidation is one of the main reactions. In meat products processing industry, the lipid composition is directly related to nutritional and sensory quality of the product. For preventing oxidation, use of antioxidants which can be synthetic or natural, has been practically applied in some products. Currently, most attention has been given to natural antioxidants from herbs and spices like rosemary and oregano. The aim this study was to assess the antioxidant effects of either rosemary and oregano extract in beef burgers submitted to irradiation in {sup 60}Co source with dose 6, 7 e 8 kGy, electron beams with dose 3,5 e 7 kGy and storage under freeze along 0, 45 e 90 days. The results showed that rosemary extract has the major antioxidant effects when it is used on heterogeneous food matrix like beef burger, but oregano extract was better efficient to delay lipid oxidation along storage time when it is used in synergism with rosemary and/or BHT/BHA. Although to have occurred changes in the fatty acids composition it was not possible to demonstrate a straight dependence of irradiation dose and/or storage time. Sensory analysis showed that between the samples prepared with natural antioxidants, the beef burger prepared with oregano has received better scores by panelists. Irradiated beef burger prepared with rosemary has received better scores when compared to non-irradiated one. The use of spices with antioxidant activity to avoid the oxidative damage in foods that contain fats in their formulation is thought to be promising to application in food facilities. (author)

  11. The Gamma-ray Sky with Fermi

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, D.J. [NASA Goddard Space Flight Center, Greenbelt, Maryland, 20771 (United States)

    2013-10-15

    Gamma rays reveal extreme, nonthermal conditions in the Universe. The Fermi Gamma-ray Space Telescope has been exploring the gamma-ray sky for more than four years, enabling a search for powerful transients like gamma-ray bursts, solar flares, and flaring active galactic nuclei, as well as long-term studies including pulsars, binary systems, supernova remnants, and searches for predicted sources of gamma rays such as clusters of galaxies. Some results include a stringent limit on Lorentz invariance violation derived from a gamma-ray burst, unexpected gamma-ray variability from the Crab Nebula, a huge gamma-ray structure in the direction of the center of our Galaxy, and strong constraints on some Weakly Interacting Massive Particle (WIMP) models for dark matter.

  12. Cosmic Rays: What Gamma Rays Can Say

    OpenAIRE

    2014-01-01

    We will review the main channels of gamma ray emission due to the acceleration and propagation of cosmic rays, discussing the cases of both galactic and extra-galactic cosmic rays and their connection with gamma rays observations.

  13. The Gamma-ray Universe through Fermi

    Science.gov (United States)

    Thompson, David J.

    2012-01-01

    Gamma rays, the most powerful form of light, reveal extreme conditions in the Universe. The Fermi Gamma-ray Space Telescope and its smaller cousin AGILE have been exploring the gamma-ray sky for several years, enabling a search for powerful transients like gamma-ray bursts, novae, solar flares, and flaring active galactic nuclei, as well as long-term studies including pulsars, binary systems, supernova remnants, and searches for predicted sources of gamma rays such as dark matter annihilation. Some results include a stringent limit on Lorentz invariance derived from a gamma-ray burst, unexpected gamma-ray variability from the Crab Nebula, a huge ga.nuna-ray structure associated with the center of our galaxy, surprising behavior from some gamma-ray binary systems, and a possible constraint on some WIMP models for dark matter.

  14. Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G0/G1 Phase Cells

    Science.gov (United States)

    Nagasawa, Hatsumi; Lin, Yu-Fen; Kato, Takamitsu A.; Brogan, John R.; Shih, Hung-Ying; Kurimasa, Akihiro; Bedford, Joel S.; Chen, Benjamin P. C.; Little, John B.

    2017-01-01

    The catalytic subunit of DNA dependent protein kinase (DNA-PKcs) and its kinase activity are critical for mediation of non-homologous end-joining (NHEJ) of DNA double-strand breaks (DSB) in mammalian cells after gamma-ray irradiation. Additionally, DNA-PKcs phosphorylations at the T2609 cluster and the S2056 cluster also affect DSB repair and cellular sensitivity to gamma radiation. Previously we reported that phosphorylations within these two regions affect not only NHEJ but also homologous recombination repair (HRR) dependent DSB repair. In this study, we further examine phenotypic effects on cells bearing various combinations of mutations within either or both regions. Effects studied included cell killing as well as chromosomal aberration induction after 0.5–8 Gy gamma-ray irradiation delivered to synchronized cells during the G0/G1 phase of the cell cycle. Blocking phosphorylation within the T2609 cluster was most critical regarding sensitization and depended on the number of available phosphorylation sites. It was also especially interesting that only one substitution of alanine in each of the two clusters separately abolished the restoration of wild-type sensitivity by DNA-PKcs. Similar patterns were seen for induction of chromosomal aberrations, reflecting their connection to cell killing. To study possible change in coordination between HRR and NHEJ directed repair in these DNA-PKcs mutant cell lines, we compared the induction of sister chromatid exchanges (SCEs) by very low fluencies of alpha particles with mutant cells defective in the HRR pathway that is required for induction of SCEs. Levels of true SCEs induced by very low fluence of alpha-particle irradiation normally seen in wild-type cells were only slightly decreased in the S2056 cluster mutants, but were completely abolished in the T2609 cluster mutants and were indistinguishable from levels seen in HRR deficient cells. Again, a single substitution in the S2056 together with a single

  15. A new type gamma-ray spectrum monitoring system

    CERN Document Server

    Cheng Bo; Zhou Jian Bin; Zhang Zhi Ming; Tong Yun Fu

    2002-01-01

    This new radiation monitoring system can be used to monitor the radiation of building materials and the radiation of atmosphere, to explore and evaluate rock for building in the field, and this system can be used to monitor the gamma irradiation near the nuclear establishments in the average situation and in the serious situation of the radiation incident have happened. The control core of this monitoring system is SCM-AT89C52, and gamma-ray sensing head consists of scintillator phi 50 mm x 50 mm NaI(Tl) and PMT GDB44. This system can be used to measure the whole gamma-ray spectrum of 256 channels

  16. 60Coγ射线半身照射对非照射区域骨髓造血组织基质细胞衍生因子1表达的影响%Influences of 60Coγray irradiation on expression stromal cell derived factor-1 in bone marrow hematopoietic tissue of non-irradiation area in left-half-body ionizing irradiated mice

    Institute of Scientific and Technical Information of China (English)

    高作文; 杨龙; 陈乐如; 娄金书; 张国强; 李开信; 程天民

    2013-01-01

    Objective To invesligale the mouse bone marrow hemalopoielic functions in non-irradiation area after irradiated by way of left-half- body. Methods The 6-8-week male Kunming strain mice were randomly divided into normal control( NC) , total-body-irradiated( TBI) , left-half-body-irradiated( LHBI) , and total-body-shield-irradia-ted( TBSI) groups. Left-half-body-irradiated group was treated with two pieces of 5 cm x 8 cm x 16 cm overlapped lead bricks shielding right-side body and irradiated with 8. 0 Gy60Coγ-ray. The leukocyte in peripheral blood and the number of bone marrow hematopoietic cells( BMHCs) were studied, the concentration of SOD, MDA in mouse serum were measured, and the expression SDF-1 in bone marrow hematopoietic tissues were observed by the Western blotting method and laser scanning confocal microscope combined with immunohistochemistry. Results In the left-half-body irradiated condition, the leucocyte in peripheral blood and the BMHCs were diminished, the concentration of MDA was increased and the SOD was decreased in the mouse serum remarkably ( compared with NC, P <0. 01) ; In non-irradiation area, the SDF-1-positive cells and the expression SDF-1 in bone marrow hematopoietic tissues were reduced significantly. Conclusion Our study suggested that the local irradiation resulted in the decrease of SDF-1-positive cells and the decline expression SDF-1 in bone marrow hematopoietic tissues in non-irradiation area, and the increase of reactive oxygen or free radicals might play an important role in the abnormal expression of SDF-1 in BMHT and the injury of hematopoietic microenvironment.%目的 探讨局部电离辐射对小鼠非照射区域骨髓造血组织基质细胞衍生因子-1(SDF-1)表达的影响.方法 将6~8周龄雄性昆明小鼠随机分为健康对照组、全身照射组、全身屏蔽照射组以及左半身照射组4组,用铅屏蔽建立半身照射模型,以8.0 Gy 60Co γ射线照射,观察小鼠外周血白细胞和骨髓有核

  17. Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations.

    Science.gov (United States)

    Peng, Yuanlin; Brown, Natalie; Finnon, Rosemary; Warner, Christy L; Liu, Xianan; Genik, Paula C; Callan, Matthew A; Ray, F Andrew; Borak, Thomas B; Badie, Christophe; Bouffler, Simon D; Ullrich, Robert L; Bedford, Joel S; Weil, Michael M

    2009-04-01

    Since deletion of the PU.1 gene on chromosome 2 is a crucial acute myeloid leukemia (AML) initiating step in the mouse model, we quantified PU.1 deleted cells in the bone marrow of gamma-, X- and 56Fe-ion-irradiated mice at various times postirradiation. Although 56Fe ions were initially some two to three times more effective than X or gamma rays in inducing PU.1 deletions, by 1 month postirradiation, the proportions of cells with PU.1 deletions were similar for the HZE particles and the sparsely ionizing radiations. These results indicate that while 56Fe ions are more effective in inducing PU.1 deletions, they are also more effective in causing collateral damage that removes hit cells from the bone marrow. After X, gamma or 56Fe-ion irradiation, AML-resistant C57BL/6 mice have fewer cells with PU.1 deletions than CBA mice, and those cells do not persist in the bone marrow of the C57B6/6 mice. Our findings suggest that quantification of PU.1 deleted bone marrow cells 1 month postirradiation can be used as surrogate for the incidence of radiation-induced AML measured in large-scale mouse studies. If so, PU.1 loss could be used to systematically assess the potential leukemogenic effects of other ions and energies in the space radiation environment.

  18. Evaluation of the effect of gamma rays on the venom of Vipera lebetina by biochemical study

    Energy Technology Data Exchange (ETDEWEB)

    Bennacef-Heffar, N.; Laraba-Djebari, F. [USTHB Bab Ezzouar, Lab. de Biologie Cellulaire et Moleculaire, Faculte des Sciences Biologiques, Alger (Algeria)]. E-mail: flaraba@ibnsina.ands.dz

    2003-12-01

    Snake bites represent a serious public health problem in many areas of the world. In Algeria, two widespread snakes are Vipera lebetina and Cerastes cerastes. Vipera lebetina venom causes local hemorrhage and necrosis, and it may lead to permanent limb loss. The principal causes of mortality after snakebites are acute renal failure and hemorrhage, which occur not only locally, at the site of the bite, but also systemically, contributing to the cardiovascular shock characteristic of severe envenomation. Gamma radiation has been shown to be effective for attenuating venom toxicity. Vipera lebetina venom was irradiated with two doses of gamma rays (1 and 2 kGy) from a {sup 60}Co source, and the venom's toxic, enzymatic, and structural properties were analyzed. Intraperitoneal injection of the irradiated venoms (100-500 {mu}g/20 g mouse body mass) revealed a significant decrease of the toxicity. Irradiated venoms with 1 and 2 kGy doses were four and nine times less toxic, respectively, than the native venom. A biochemical characterization of in vitro enzymatic activities was performed. Vipera lebetina displayed in vitro caseinolytic, amidolytic, esterasic, coagulant, and phospholipase A{sub 2} activities. Caseinolytic, amidolytic, esterasic, and coagulative activities were reduced for the irradiated venoms; only phospholipase A{sub 2} activity was abolished in the irradiated venom with a dose of 2 kGy. The native and irradiated venoms were separated by gel filtration and electrophoresis. Chromatographic and electrophoretic profiles were drastically changed as compared with the native venom. Vipera lebetina venom detoxified by gamma rays was used for active immunization, and the presence of antibody in the immune sera was detected by ELISA. The immunogenic properties were preserved and the antisera obtained with the irradiated venoms could cross-react. Antisera were able to neutralize the toxic effect of V. lebetina native venom. These results indicate that

  19. Study on the Immune Protective Effect of Sophora japonical Water Extract on the Spleen Cells of 60Co-γ Ray Irradiated Injured Mice%槐白皮水提物对60Co-γ射线损伤小鼠脾细胞的免疫保护作用研究

    Institute of Scientific and Technical Information of China (English)

    张跃进; 董海艳; 张婵; 李安乐; 陈向敏

    2012-01-01

    目的:研究槐白皮水提物对50Co-γ射线损伤小鼠脾细胞的免疫保护作用.方法:实验分为5组,即正常(等容生理盐水)、照射对照(等容生理盐水)和槐白皮水提物高、中、低剂量(0.8、0.4、0.2 mL·kg-1)组.除正常组外其余各组给予60Co-γ射线一次性照射,照射后立即给药,每天1次,连续10d.测定小鼠脾细胞培养上清液中一氧化氮(NO)水平及脾指数.结果:槐白皮水提物中剂量组NO含量显著低于照射对照组(P<0.05);槐白皮水提物中、低剂量组脾指数显著高于照射对照组(P<0.01或P<0.05).结论:槐白皮水提物能降低射线对脾细胞的损伤,具有免疫保护作用.%OBJECTIVE: To evaluate the immune protective effect of Sophora japonical water extract on the spleen cells of 6cCo-y ray irradiated injured mice. METHODS: Mice were randomly divided into 5 groups: normal group (constant volume normal saline), irradiation control group (constant volume normal saline) ,S. Japonical water extract high-dose, medium-dose and low-dose groups(0.8, 0.4, and 0.2 mL?kg"'). All the mice were irradiated with Mco-y ray except normal group, and then S. Japonical water extract was given once a day for 10 days. And then nitric oxide (NO) level and spleen index was detected in spleen cell of mice. RESULTS: NO level of S. Japonical water extract medium-dose group was significantly lower than irradiation control group(P< 0.01), and the spleen index of S. Japonical water extract medium-doce group and low-dose groups was significantly higher than irradiation control group(f <0.01 or P<0.05). CONCLUSIONS: S. Japonical water extract can reduce the damage of the irradiated spleen cells, and have the immune protective function.

  20. Gamma rays from dark matter

    CERN Document Server

    Bringmann, Torsten

    2011-01-01

    A leading hypothesis for the nature of the elusive dark matter are thermally produced, weakly interacting massive particles that arise in many theories beyond the standard model of particle physics. Their self-annihilation in astrophysical regions of high density provides a potential means of indirectly detecting dark matter through the annihilation products, which nicely complements direct and collider searches. Here, I review the case of gamma rays which are particularly promising in this respect: distinct and unambiguous spectral signatures would not only allow a clear discrimination from astrophysical backgrounds but also to extract important properties of the dark matter particles; powerful observational facilities like the Fermi Gamma-ray Space Telescope or upcoming large, ground-based Cherenkov telescope arrays will be able to probe a considerable part of the underlying, e.g. supersymmetric, parameter space. I conclude with a more detailed comparison of indirect and direct dark matter searches, showing...

  1. DUAL Gamma-Ray Mission

    CERN Document Server

    Boggs, S; von Ballmoos, P; Takahashi, T; Gehrels, N; Tueller, J; Baring, M; Beacom, J; Diehl, R; Greiner, J; Grove, E; Hartmann, D; Hernanz, M; Jean, P; Johnson, N; Kanbach, G; Kippen, M; Knödlseder, J; Leising, M; Madejski, G; McConnell, M; Milne, P; Motohide, K; Nakazawa, K; Oberlack, U; Phlips, B; Ryan, J; Skinner, G; Starrfield, S; Tajima, H; Wulf, E; Zoglauer, A; Zych, A

    2010-01-01

    Gamma-ray astronomy presents an extraordinary scientific potential for the study of the most powerful sources and the most violent events in the Universe. In order to take full advantage of this potential, the next generation of instrumentation for this domain will have to achieve an improvement in sensitivity over present technologies of at least an order of magnitude. The DUAL mission concept takes up this challenge in two complementary ways: a very long observation of the entire sky, combined with a large collection area for simultaneous observations of Type Ia SNe. While the Wide-Field Compton Telescope (WCT) accumulates data from the full gamma-ray sky (0.1-10 MeV) over the entire mission lifetime, the Laue-Lens Telescope (LLT) focuses on 56Co emission from SNe Ia (0.8-0.9 MeV), collecting gamma-rays from its large area crystal lens onto the WCT. Two separated spacecraft flying in formation will maintain the DUAL payloads at the lens' focal distance.

  2. Effect of serial irradiation of low dose gamma rays on the growth and photosynthesis of red pepper (capsicum annuum L.) plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin Hong; Wi, Seung Gon; Chung, Byung Yeoup; Baek, Myung Hwa; Yang, Dae Hwa; Kim, Jae Sung [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2004-07-01

    Ionizing radiation at several grays can induce growth stimulation in plants. This phenomenon has been called 'radiation hormesis'. Low dose radiation also modulates photosynthesis. Although an alteration in photosynthesis has been thought to involve in the growth stimulation of irradiated plants, no reports did clarify their relationship yet. In the present study, we attempted to reveal a possible relationship between them by comparing the effects of serial gamma-irradiation on the growth and photosynthesis of red pepper. Furthermore, something beyond the dose effect of ionizing radiation is discussed by this new experimental approach.

  3. Effects of gamma irradiation of the {sup 60} Co on antimicrobial action of plant extracts of bark and leaves of Schinus terebinthifolius Raddi; Efeitos da radiacao gama do {sup 60} Co sobre a acao antimicrobiana de extratos vegetais de cascas e folhas de Schinus terebinthifolius Raddi

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Edvane Borges da; Santos, Gustavo Henrique Farias dos; Amaral, Ademir de Jesus [Universidade Federal da Pernambuco (GERAR/DEN/UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear. Grupo de Estudos em Radioprotecao e Radioecologia; Lima, Jeniffer Maiza de Souza [Universidade Federal da Pernambuco (CAV/UFPE), Vitoria de Santo Antao, PE (Brazil); Xisto, Kesia; Araujo, Rosilma de Oliveira [Universidade Federal da Pernambuco (DA/UFPE), Recife, PE (Brazil). Dept. de Antibioticos

    2014-07-01

    This study aimed to evaluate the potential for antimicrobial activity in vitro of extracts of bark and leaves of S. terebinthifolius treated with {sup 60}Co gamma radiation. 5,0 doses were used; 7.5 and 10 kGy, being held non-irradiated controls. To determine the antimicrobial activity was applied to the disc diffusion technique to evaluate the diameter of the inhibition zones against Gram-positive bacteria, gram-negative bacteria, alcohol-acid-resistant and yeast. Antimicrobial activity was considered significant for halos ≥ 15 mm. The results indicate an intensification of antimicrobial action of bark extracts, the 5.0 kGy, against S. aureus. Was held the micro dilution in broth to determine the minimum inhibitory concentration (MIC) and Minimum Bactericidal Concentration (MBC) of peels extracts, compared to eight clinical isolates of S. aureus. The MBC values showed that ionizing radiation did not produce the increased of anti bacteriostatic action of S. terebinthifolius, but the results indicated that S. terebinthifolius bark extracts can be used as an antimicrobial agent and ionizing radiation as an important alternative in this conservation feature.

  4. Research of Effect of 60Co γ-ray Irradiation on Cell Cycle of SMMC, 7721 Tumor Cell with Flow Cytometery

    Institute of Scientific and Technical Information of China (English)

    DangBingrong; MaQiufeng; GaoQingxiang; LiWenjian; HaoJifang; XieYi; GuoChuanling

    2003-01-01

    The resultsMost researchof cell cycle play an important role in resear, ching tumor occurrence, development and treatment. results show that malignant grade and pharmic sensitivity of tumor are relative to cell cycle. The sensitivity of medications is different to different phases of cell cycle of tumor. In general, the cell of M are more sensitivity. On the side, different medications have different action in different cell cycle. The irradiation can change cell cycle proccss and can induce the pattern of changes in cell cycle. For cxamplc, G1 arrest, G2 arrest and S arrest. So, thc research rcsults of tumor cell cycle in different irradiation have not only biological means but also realistic means for selecting chemical therapy medication after radiotherapy.

  5. 钴60γ射线灭活人工骨钉PRV病毒效果验证%Validation of porcine pesudorabies virus inactivation by gamma rays irradiation from cobalt 60

    Institute of Scientific and Technical Information of China (English)

    钱垂文; 张美英; 徐斌; 王一飞

    2012-01-01

    目的:验证钴60辐照灭活猪源性人工骨钉中指示病毒PRV活性的有效性.方法:首先利用CPE法测定不同辐照剂量γ射线灭活样品后指示病毒的感染活性,初步确定有效辐照剂量;然后利用三批样品对该辐照剂量灭活效果进行验证,辐照前后人工骨钉中指示病毒的滴度采用96孔板CPE法滴定.结果:CPE法测定结果显示,经20kGy及以上辐照剂量处理的样品中指示病毒PRV不能使宿主细胞PK-15出现细胞病变;三批样品经20kGy辐照剂量处理后,指示病毒PRV滴度下降值⊿lgTCID50分别>4.06,>4.75,>4.28,⊿lgTCID50值均大于4.结论:辐照剂量为20kGy的钴60γ射线辐照猪源性人工骨钉可以作为灭活PRV的有效手段.%Objective:To validate the indicating virus inactivation in artificial bone screw by Gamma Rays Irradiation from Cobalt 60. Methods; The indicating virus PRV virulence was determined with irradiation at different dosages (lOkGy, 15 kGy, 20 kGy, 25 kGy) by cytopathogenic effect (CPE) method, then the effective irradiation dose to inactivate the PRV in artificial bone screw was set, three batch products were used to validate the inactivation effect next. The liter of PRV was assayed with 96 - well plate by CPE method. Results:CPE results showed indicating virus PRV in artificial bone screw treated with irradiation dose at 2OkGy or more, cannot make PK -15 cells have pathological changes. After irradiation, the logarithm value of PRV titer of three batch product reduced more than 4.06,4.75,4. 28 respectively. The logarithm values were more than 4. Conclusion:It was an effective method to inactivate PRV in artificial bone screw with 2OkGy irradiation from Cobalt 60.

  6. Effect of Gamma Ray Irradiation on Epitaxial Pb(Zr,Ti)O3 /SrRuO3 Tunable Varactor Devices

    Science.gov (United States)

    Barala, Surendra Singh; Banerjee, Nirupam; Kumar, Mahesh

    2016-08-01

    Epitaxial morphotropic PbZr0.52Ti0.48O3 (PZT) thin films were employed to enhance the dielectric tunability of microwave filter devices without compromising the device impedance matching and low bias voltage (<10 V) requirements. Epitaxial heterostructure of ferroelectric PZT(001)/SrRuO3 (SRO) were grown on single crystal SrTiO3 (001) substrates by pulsed laser deposition, and a platinum (Pt) electrode was deposited on top of the PZT film. The tunability of the Pt/PZT/SRO varactor devices are strongly dependent on bias voltage and exhibited good dielectric tunability of 55% at 100 kHz and 10 V. The capacitance ( C P) of the heteroepitaxial varactor devices was 105 pF at 10 V applied bias with a corresponding small leakage current of 1 nA. The influence of gamma ( γ-ray) irradiation on the intrinsic electrical properties of the epitaxial PZT varactor devices was investigated as a function of the irradiation dose from 0 kGy to 400 kGy, in terms of the capacitance-voltage ( C- V) characteristics and loss tangent response. With enhancing γ-ray irradiation doses the ferroelectric capacitance was found to decrease accompanying degradation in the loss tangent values. The results indicate that tunability of the epitaxial PZT ferroelectric thin-film capacitors decreased with increasing gamma irradiation dose and degraded ˜25% at 400 kGy dose than unexposed devices. Possible reasons for the degradation behavior of dielectric properties and tunability due to radiation-induced defects has been discussed.

  7. Protective Influence of Gamma Rays and Electron-Beam Irradiation with a Commercial Toxin Binder on Toxic Effects of Aflatoxin B1 in Japanese Quails

    Directory of Open Access Journals (Sweden)

    Saeed Hasanpour

    2015-11-01

    Full Text Available Background: This cross sectional study was conducted to evaluate the effect of γ-rays and electron-beam irradiation with a commercial toxin binder-milbond-TX on the performance, feed components, and meat quality of Japanese quails challenged with aflatoxin B1. Methods: Overall, 168 One-d-old chicks (Japanese quails were allocated to eight treatments with three replicates based on a completely randomized design in a 2×4 factorial arrangement. Two levels of aflatoxin (Zero and 2 ppm were considered as the essential factor. The secondary factor was involved in four levels (Control, 27 k Gy doses of γ-rays, electron-beam irradiation, and 0.3% commercial toxin binder-milbond-TX. Results: In vitro condition showed that experiment diets do not have any effect on meat quality and feed components such as malondialdehyde, protein, fat, ash, and the dry matter. However, the highest and the lowest levels of feed intake and body weight gain were observed in the 7th treatment (2-ppm aflatoxin B1 + electron-beam irradiation and the 2nd treatment (2-ppm aflatoxin B1 alone, respectively in 1-15 and 29-42 days (P≤0.05. In addition, the highest liver weight (1.73, spleen (0.57 and bursa (0.18 were seen in the second treatment (2 ppm aflatoxin B1 alone (P≤0.05 at the age of 42 days. Conclusion: γ-rays and electron-beam irradiation plus commercial toxin binder-milbond-TX can be used for aflatoxin B1 absorption in poultry diets.

  8. Irradiation with ultraviolet light and gamma-rays increases the level of DNA topoisomerase II in nuclei of normal and xeroderma pigmentosum fibroblasts.

    Science.gov (United States)

    Thielmann, H W; Popanda, O

    1998-02-01

    DNA topoisomerase II was monitored with the monoclonal antibody Ki-S1 in human fibroblasts after irradiation of cells with 254-nm UV light and -rays from a 137Cs source. DNA topoisomerase II was localized immunohistochemically as bright fluorescent dots in the karyoplasm. Investigated fibroblasts originated from normal human donors and a xeroderma pigmentosum patient (XP12BE). All cell lines showed a time and dose-dependent increase in DNA topoisomerase II abundance after irradiation. The increase may reflect enhanced accessibility of the enzyme, enhanced gene expression or enhanced stabilization of mRNA or protein molecules. The effect was detectable as early as 1 h after irradiation at doses 3 J/m2 or 3 Gy. It passed through a maximum and decreased within 18 h (UV light) or 6 h ( -rays). Except for the duration of the response, no principal differences were seen between the effects caused by UV light and those elicited by -rays. The increase in enzyme levels might be part of the well-known DNA damage responses which operate in cell-protective or DNA-reparative pathways or may reflect initiation of apoptosis. DNA topoisomerase I was detected with a commercially available polyclonal antibody raised against human DNA topoisomerase I. In unirradiated cells, DNA topoisomerase I was found to be mainly concentrated in nucleoli. Irradiation with -rays changed the staining pattern in that it caused a multitude of DNA topoisomerase I-rich centers to occur which may reflect sites of transcription of radiation-inducible genes.

  9. 60Co γ射线辐照预处理对甘薯热风干燥特性的影响%INFLUENCE OF 60Co γ IRRADIATION PRE-TREATMENT ON CHARACTERISTICS OF HOT AIR DRYING SWEET POTATO SLICES

    Institute of Scientific and Technical Information of China (English)

    江宁; 刘春泉; 李大婧; 刘霞; 严启梅

    2012-01-01

    The influences of irradiation, hot air temperature and thicknesses of the slices on the characters of dehydration and surface temperature of 60Co γ-rays irradiated sweet potato were investigated. Meanwhile, microscopic observation and determination of water activity of irradiated sweet potato were conducted. The results show that the drying rate and the surface temperature rised with the increasing of irradiation dose. When the dry basis moisture content was 150% , the drying rate of the samples were 1.92, 1.97, 2.05, 2.28, 3.12%/min while the irradiation dose were 0, 2, 5, 8, 10kGy, and the surface temperature were 48.5℃ , 46.3℃ , 44.5℃, 42.2℃, 41.5℃ , respectively. With higher air temperature and thinner of the sweet potato slices, the dehydration of the irradiated sweet potato slices were faster. The drying speed of sweet potato slices at 85℃ was 170min faster than that of 65℃. The drying speed of 7mm sweet potato slices was 228min faster than that of 3mm sample. The cell wall and the vacuole of the sweet potato slices were broken after irradiation, and its water activity increased with the inorease is radiation dose. The water activity of the irradiated samples were 0. 92, 0. 945, 0. 958, 0. 969, 0. 979 with the irradiation doses of 0, 2, 5, 8, 10kGy, respectively. The hot air drying rate, surface temperature and water activity of sweet potato are significantly impacted by irradiation. The conclusion provids a theoretical foundation for further processing techonology of combined radiation and hot air drying sweet potato.%采用60Coγ射线对甘薯进行辐照预处理,考察辐照、热风温度和切片厚度对其干燥特性和表面温度的影响,同时对不同剂量辐照的甘薯样品进行了显微观察和水分活度测定。结果表明,甘薯的干燥速率和表面温度随着辐照剂量的升高而升高。当干基含水率为150%时,辐照剂量为0、2、5、8和10kGy的样品干燥速率分别为1.92、1.97、2.05、2.28和3

  10. In vitro response of the human breast cancer cell line MDAMB-231 and human peripheral blood mononuclear cells exposed to {sup 60}Co at single fraction

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Lidia Maria; Campos, Tarcisio Passos Ribeiro de [Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear]. E-mail: lidia.andrade@unifenas.br; Leite, M.F. [Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil). Dept. de Fisiologia e Biofisica; Goes, A.M. [Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil). Dept. de Bioquimica e Imunologia

    2005-10-15

    Radiotherapy using gamma rays is a common modality of breast cancer treatment. The aim of this research is to investigate the biological response of the human breast cancer cell line MDAMB-231 and human peripheral blood mononuclear cells (PBMC) exposed in vitro to {sup 60} Co irradiation at a single fraction of 10 Gy, 25 Gy and 50 Gy doses at 136,4 cGy.min{sup -1} rate. Cells were irradiated at room temperature by the Theratron 80 radiotherapy system. Biological response was evaluated through cellular viability using MTT assay and nucleus damages visualized by Propidium Iodide assay and electrophoresis agarose gel after gamma irradiation. Nucleus damages induced by {sup 60} Co irradiation were compared to damage caused by cell exposure to 10% methanol. The 50 Gy dose of irradiation did not stimulate nucleus damages at the same level as that affected by 10% methanol induction in the MDAMB-231. Further studies are necessary to understand these mechanisms in the MDAMB-231 human breast carcinoma cell line.(author)

  11. [Changes in the quantity of aldehydes, peroxides, the iodine and saponification number in bovine and swine fats following irradiation with gamma-rays].

    Science.gov (United States)

    Lordanov, I

    1975-01-01

    The studies were carried out during the process of storing fats obtained from cattle and pigs under refrigeration conditions at plus and minus temperatures. The production of peroxides and epihydrinaldehyde in the fats after irradiation and during storage depended on the presence of oxygen, the rate of treatment, the temperature, and the period of storage. The intensity of production of peroxides and epihydrinaldehyde in the bovine fats was higher than in swine fats. Gamma-treatment at 2.00 Mrad had no effect on the changes of the iodine number and the index of saponification.

  12. Thermal stability of formulations of PVC irradiated with {gamma} of {sup 60}; Estabilidad termica de formulaciones de PVC irradiadas con {gamma} de {sup 60} Co

    Energy Technology Data Exchange (ETDEWEB)

    Martinez P, M.E.; Carrasco A, H. [ININ, A.P. 18-1027, 11801 Mexico D.F. (Mexico)]. E-mail: memp@nuclear.inin.mx; Castaneda F, A.; Benavides C, R.; Garcia R, S.P. [CIQA, 25100 Saltillo, Coahuila (Mexico)

    2004-07-01

    The industry of cables and wires frequently use cable isolations with base of formulations of PVC, in those that stabilizer has usually been used with the help of heavy metals, as the lead, which is toxic. To solve the problem, from the 2002 one has come studying in combined form in the National Institute of Nuclear Research ININ and the Center of Investigation in Applied Chemistry CIQA, the modifications induced by the radiation in formulations with the help of vinyl poly chloride PVC. In these formulations, prepared with cross linking agent, plastifying industrial grade, stuff and non toxic stabilizers of calcium estearate and zinc industrial grade, it is sought to replace the stabilizer of Pb. For this were irradiated it test tubes of PVC with gamma radiation of cobalt 60 to three different dose in atmospheres of air and argon. Later it was determined their thermal stability at different times of heating and it was measured the Young modulus by means of thermo mechanical analysis. Those results obtained together with other techniques of characterization suggest that the irradiated proposed formulation can substitute the one stabilized with lead. (Author)

  13. Radiation inactivation of Paenibacillus larvae and sterilization of American Foul Brood (AFB) infected hives using Co-60 gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    De Guzman, Zenaida M. [Microbiological Research and Service Laboratory, Atomic Research Division, Philippine Nuclear Research Institute, Diliman, Quezon City (Philippines); Cervancia, Cleofas R. [Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines, Los Banos, Laguna (Philippines); Dimasuay, Kris Genelyn B.; Tolentino, Mitos M.; Abrera, Gina B.; Cobar, Ma. Lucia C. [Microbiological Research and Service Laboratory, Atomic Research Division, Philippine Nuclear Research Institute, Diliman, Quezon City (Philippines); Fajardo, Alejandro C.; Sabino, Noel G.; Manila-Fajardo, Analinda C. [Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines, Los Banos, Laguna (Philippines); Feliciano, Chitho P., E-mail: cpfeliciano@pnri.dost.gov.ph [Microbiological Research and Service Laboratory, Atomic Research Division, Philippine Nuclear Research Institute, Diliman, Quezon City (Philippines); Institute of Biology, College of Science, University of the Philippines, Diliman, Quezon City (Philippines)

    2011-10-15

    The effectiveness of gamma radiation in inactivating the Philippine isolate of Paenibacillus larvae was investigated. Spores of P. larvae were irradiated at incremental doses (0.1, 0.2, 0.4, 0.8 and 1.6 kGy) of gamma radiation emitted by a {sup 60}Co source. Surviving spores were counted and used to estimate the decimal reduction (D{sub 10}) value. A dose of 0.2 kGy was sufficient to inactivate 90% of the total recoverable spores from an initial count of 10{sup 5}-9x10{sup 3} spores per glass plate. The sterilizing effect of high doses of gamma radiation on the spores of P. larvae in infected hives was determined. In this study, a minimum dose (D{sub min}) of 15 kGy was tested. Beehives with sub-clinical infections of AFB were irradiated and examined for sterility. All the materials were found to be free of P. larvae indicating its susceptibility to {gamma}-rays. After irradiation, there were no visible changes in the physical appearance of the hives' body, wax and frames. Thus, a dose of 15 kGy is effective enough for sterilization of AFB-infected materials. - Highlights: > We characterized Paenibacillus larvae and determined its radiation sensitivity. > We investigated the effectiveness of gamma rays in inactivating P. larvae. > Gamma radiation inactivates P. larvae. > 15 kGy is effective for the sterilization of P. larvae-infected hives. > Irradiation produces no visible changes in the hives' body, waxes and frames.

  14. High Redshift Gamma Ray Bursts

    Science.gov (United States)

    Gehrels, Neil

    2012-01-01

    The Swift Observatory has been detecting 100 gamma-ray bursts per year for 7 years and has greatly stimulated the field with new findings. Observations are made of the X-ray and optical afterglow from 1 minute after the burst, continuing for days. GRBs are providing a new tool to study the high redshift universe. Swift has detected several events at z>5 and one at z=9.4 giving information on metallicity, star formation rate and reionization. The talk will present the latest results.

  15. On-line interrogation of pebble bed reactor fuel using passive gamma-ray spectrometry

    Science.gov (United States)

    Chen, Jianwei

    with the relative activities of Cs-134/Co-60 (Co-60 is introduced as a dopant) to yield the burnup and enrichment for each pebble. Furthermore, a direct consequence of the relative approach is the ability to apply a self-calibration scheme using the multiple gamma lines of Ba-La-140 to establish the relative efficiency curve of the HPGe detector. An assessment of the expected uncertainty components in this approach showed that a maximum uncertainty of less than 5% should be feasible. To confirm the above findings, gamma-ray scans were performed on irradiated PULSTAR reactor fuel assemblies at North Carolina Sate University. The measurements used a 40% efficient n-type coaxial HPGe detector connected to an ORTEC DSPEC plus digital Gamma-Ray Spectrometer, and a data acquisition computer. The obtained results showed consistency with the predictions of the simulations including the observation of the I-132, Cs-134, Np-239 uncontaminated gamma lines. In addition, the Ba-La-140 lines were clearly observed confirming the ability to perform relative calibration of the spectrometer.

  16. Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles.

    Science.gov (United States)

    Lin, Yu-Fen; Nagasawa, Hatsumi; Little, John B; Kato, Takamitsu A; Shih, Hung-Ying; Xie, Xian-Jin; Wilson, Paul F; Brogan, John R; Kurimasa, Akihiro; Chen, David J; Bedford, Joel S; Chen, Benjamin P C

    2014-01-01

    We have examined cell-cycle dependence of chromosomal aberration induction and cell killing after high or low dose-rate γ irradiation in cells bearing DNA-PKcs mutations in the S2056 cluster, the T2609 cluster, or the kinase domain. We also compared sister chromatid exchanges (SCE) production by very low fluences of α-particles in DNA-PKcs mutant cells, and in homologous recombination repair (HRR) mutant cells including Rad51C, Rad51D, and Fancg/xrcc9. Generally, chromosomal aberrations and cell killing by γ-rays were similarly affected by mutations in DNA-PKcs, and these mutant cells were more sensitive in G1 than in S/G2 phase. In G1-irradiated DNA-PKcs mutant cells, both chromosome- and chromatid-type breaks and exchanges were in excess than wild-type cells. For cells irradiated in late S/G2 phase, mutant cells showed very high yields of chromatid breaks compared to wild-type cells. Few exchanges were seen in DNA-PKcs-null, Ku80-null, or DNA-PKcs kinase dead mutants, but exchanges in excess were detected in the S2506 or T2609 cluster mutants. SCE induction by very low doses of α-particles is resulted from bystander effects in cells not traversed by α-particles. SCE seen in wild-type cells was completely abolished in Rad51C- or Rad51D-deficient cells, but near normal in Fancg/xrcc9 cells. In marked contrast, very high levels of SCEs were observed in DNA-PKcs-null, DNA-PKcs kinase-dead and Ku80-null mutants. SCE induction was also abolished in T2609 cluster mutant cells, but was only slightly reduced in the S2056 cluster mutant cells. Since both non-homologous end-joining (NHEJ) and HRR systems utilize initial DNA lesions as a substrate, these results suggest the possibility of a competitive interference phenomenon operating between NHEJ and at least the Rad51C/D components of HRR; the level of interaction between damaged DNA and a particular DNA-PK component may determine the level of interaction of such DNA with a relevant HRR component.

  17. Gravitational microlensing of gamma-ray blazars

    DEFF Research Database (Denmark)

    F. Torres, Diego; E. Romero, Gustavo; F. Eiroa, Ernesto;

    2003-01-01

    We present a detailed study of the effects of gravitational microlensing on compact and distant $\\gamma$-ray blazars. These objects have $\\gamma$-ray emitting regions which are small enough as to be affected by microlensing effects produced by stars lying in intermediate galaxies. We analyze...... the temporal evolution of the gamma-ray magnification for sources moving in a caustic pattern field, where the combined effects of thousands of stars are taken into account using a numerical technique. We propose that some of the unidentified $\\gamma$-ray sources (particularly some of those lying at high...... galactic latitude whose gamma-ray statistical properties are very similar to detected $\\gamma$-ray blazars) are indeed the result of gravitational lensing magnification of background undetected Active Galactic Nuclei (AGNs)....

  18. Gamma-Ray Astronomy Technology Needs

    Science.gov (United States)

    Gehrels, N.; Cannizzo, J. K.

    2012-01-01

    In recent decades gamma-ray observations have become a valuable tool for studying the universe. Progress made in diverse 8re1lS such as gamma-ray bursts (GRBs), nucleosynthesis, and active galactic nuclei (AGNs) has complimented and enriched our astrophysical understanding in many ways. We present an overview of current and future planned space y-ray missions and discussion technology needs for- the next generation of space gamma-ray instruments.

  19. Gamma-ray induced variability in greengram

    Energy Technology Data Exchange (ETDEWEB)

    Verma, R.K.; Singh, D.P. (Gobind Ballabh Pant Univ. of Agriculture and Technology, Pantnagar (India))

    1984-04-01

    Dry seeds of 'Pusa Baisakhi' greengram (vigna radiata (Linn.) Wilczek) were exposed to /sup 60/CO at doses of 20, 30, 40 and 50 kR. The mean days to maturity, plant height, pods/cluster and 100-seed weight increased at all the doses except at 50 kR for days to maturity. There was a decrease in the mean number of seeds/pods, as well as in pods, clusters, seeds and yield/plant. The irradiated populations showed higher variance over the control at all doses in the M/sub 3/ generation.

  20. Magnetars and Gamma Ray Bursts

    CERN Document Server

    Bucciantini, N

    2012-01-01

    In the last few years, evidences for a long-lived and sustained engine in Gamma Ray Bursts (GRBs) have increased the attention to the so called millisecond-magnetar model, as a competitive alternative to the standard collapsar scenario. I will review here the key aspects of the {\\it millisecond magnetar} model for Long Duration Gamma Ray Bursts (LGRBs). I will briefly describe what constraints, present observations put on any engine model, both in term of energetic, outflow properties, and the relation with the associated Supernova (SN). For each of these I will show how the millisecond magnetar model satisfies the requirements, what are the limits of the model, how can it be further tested, and what observations might be used to discriminate against it. I will also discuss numerical results that show the importance of the confinement by the progenitor star in explaining the formation of a collimated outflow, how a detailed model for the evolution of the central engine can be built, and show that a wide varie...

  1. Gamma-ray burst models.

    Science.gov (United States)

    King, Andrew

    2007-05-15

    I consider various possibilities for making gamma-ray bursts, particularly from close binaries. In addition to the much-studied neutron star+neutron star and black hole+neutron star cases usually considered good candidates for short-duration bursts, there are also other possibilities. In particular, neutron star+massive white dwarf has several desirable features. These systems are likely to produce long-duration gamma-ray bursts (GRBs), in some cases definitely without an accompanying supernova, as observed recently. This class of burst would have a strong correlation with star formation and occur close to the host galaxy. However, rare members of the class need not be near star-forming regions and could have any type of host galaxy. Thus, a long-duration burst far from any star-forming region would also be a signature of this class. Estimates based on the existence of a known progenitor suggest that this type of GRB may be quite common, in agreement with the fact that the absence of a supernova can only be established in nearby bursts.

  2. Efeito da irradiação (60Co na frequência fúngica de amendoim in natura em função do tempo de prateleira Gamma-irradiation effect (60Co in fungi frequency of peanut in natura and after storage

    Directory of Open Access Journals (Sweden)

    Guilherme Prado

    2006-10-01

    Full Text Available Foi verificado o efeito da irradiação gama (60Co na capacidade de destruir a microbiota fúngica, em amendoim em grão, cultivar Tatu Vermelho, da safra 2003 (segundo semestre. Os grãos de amendoim, após a irradiação, foram mantidos à temperatura ambiente em embalagem plástica comercial, durante 180 dias. Para a determinação da porcentagem fúngica foi utilizada a técnica do plaqueamento direto utilizando o meio Ágar Dicloran Rosa de Bengala Cloranfenicol (DRBC, desinfetando ou não os grãos com solução de hipoclorito de sódio. Em grãos de amendoim irradiados e desinfetados externamente, observou-se redução da infecção fúngica a 5 kGy e destruição total de fungos a 10 kGy, após 180 dias de armazenamento à temperatura ambiente. Em grãos irradiados e não desinfetados externamente foram verificados, em função do tempo de armazenamento, aumento da população de fungos com a dose de 1 kGy, redução com a dose de 5 kGy e eliminação total com a aplicação de 10 kGy. A irradiação gama, na dose de 10 kGy ou superior, demonstrou ser um processo eficaz na redução da microbiota fúngica de amendoim em grão, cultivar Tatu Vermelho.Gamma-irradiation effect was verified on the capability of destroying the mycoflora of peanuts grain, Tatu Vermelho cultivar, 2003 crop (second semester. The peanuts grains, after irradiation, were kept at room temperature in plastic bags during 180 days. To determine the percentage of fungi, the direct plating technique was used and the grains were plated out on mycological media dicholoran rose bengal chloranphenicol (DRBC, being desinfected or not with sodium hypochlorite solution. Irradiated and desinfected peanuts was observed a reduction of fungi infection at 5 kGy and total fungi destruction at 10 kGy, after 180 days in storage at room temperature. Irradiated and non desinfected grains showed a increase of fungi population with 1 kGy dose, reduction with 5 kGy dose and total

  3. Monte Carlo simulation of gamma ray tomography for image reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Guedes, Karlos A.N.; Moura, Alex; Dantas, Carlos; Melo, Silvio; Lima, Emerson, E-mail: karlosguedes@hotmail.com [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil); Meric, Ilker [University of Bergen (Norway)

    2015-07-01

    The Monte Carlo simulations of known density and shape object was validate with Gamma Ray Tomography in static experiments. An aluminum half-moon piece placed inside a steel pipe was the MC simulation test object that was also measured by means of gamma ray transmission. Wall effect of the steel pipe due to irradiation geometry in a single pair source-detector tomography was evaluated by comparison with theoretical data. MCNPX code requires a defined geometry to each photon trajectory which practically prevents this usage for tomography reconstruction simulation. The solution was found by writing a program in Delphi language to create input files automation code. Simulations of tomography data by automated MNCPX code were carried out and validated by experimental data. Working in this sequence the produced data needed a databank to be stored. Experimental setup used a Cesium-137 isotopic radioactive source (7.4 × 109 Bq), and NaI(Tl) scintillation detector of (51 × 51) × 10−3 m crystal size coupled to a multichannel analyzer. A stainless steel tubes of 0,154 m internal diameter, 0.014 m thickness wall. The results show that the MCNPX simulation code adapted to automated input file is useful for generating a matrix data M(θ,t), of a computerized gamma ray tomography for any known density and regular shape object. Experimental validation used RMSE from gamma ray paths and from attenuation coefficient data. (author)

  4. Origin of $\\gamma$ Ray Bursters

    CERN Document Server

    Mészáros, P

    1999-01-01

    The successful discovery of X-ray, optical and radio afterglows of GRB hasmade possible the identification of host galaxies at cosmological distances.The energy release inferred in these outbursts place them among the mostenergetic and violent events in the Universe. They are thought to be theoutcome of a cataclysmic stellar collapse or compact stellar merger, leading toa relativistically expanding fireball, in which particles are accelerated atshocks and produce nonthermal radiation. The substantial agreement betweenobservations and the theoretical predictions of the fireball shock modelprovide confirmation of the basic aspects of this scenario. Among recent issuesare the collimation of the outflow and its implications for the energetics, theproduction of prompt bright flashes at wavelenghts much longer than gamma-rays,the time structure of the afterglow, its dependence on the central engine orprogenitor system behavior, and the role of the environment on the afterglow.

  5. Investigation of the /sup 59/Co(n,. gamma. )/sup 60/Co reaction with unpolarized and polarized neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Kopecky, J. (Stichting Energieonderzoek Centrum Nederland, Petten. Nuclear Structure Group); Delfini, M.G. (Stichting Energieonderzoek Centrum Nederland, Petten. Nuclear Structure Group; Rijksuniversiteit Utrecht (Netherlands). Fysisch Lab.); Chrien, R.E. (Brookhaven National Lab., Upton, NY (USA))

    1984-10-15

    Capture of 24 keV neutrons and polarized as well as unpolarized thermal neutrons in /sup 59/Co has been investigated. Of the 350 ..gamma..-rays observed 335 could be placed in a /sup 60/Co level scheme containing 144 levels. The reaction Q-value amounts to 7491.92(8) keV. The chi/sup 2/ analysis of the circularly polarized ..gamma..-rays results in 31 unambiguous spin assignments for /sup 60/Co levels. The fraction of the J=4/sup -/ channel in the thermal capture was determined to be (80 +- 1)%. An average ..gamma..-ray multiplicity of 2.3 gammas per neutron capture was observed. The resulting level scheme is compared to shell-model predictions. Possible reaction mechanisms are discussed.

  6. Effects of 900-MHz microwave radiation on gamma-ray-induced damage to mouse hematopoietic system.

    Science.gov (United States)

    Cao, Yi; Xu, Qian; Jin, Zong-Da; Zhang, Jun; Lu, Min-Xia; Nie, Ji-Hua; Tong, Jian

    2010-01-01

    Exposure of humans simultaneously to microwave and gamma-ray irradiation may be a commonly encountered phenomenon. In a previous study data showed that low-dose microwave radiation increased the survival rate of mice irradiated with 8Gy gamma-ray; however, the mechanisms underlying these findings remain unclear. Consequently, studies were undertaken to examine the effects of microwave exposure on hematopoietic system adversely altered by gamma-ray irradiation in mice. Preexposure to low-dose microwaves attenuated the damage produced by gamma-ray irradiation as evidenced by less severe pathological alterations in bone marrow and spleen. The protective effects of microwaves were postulated to be due to up-expression of some hematopoietic growth factors, stimulation of proliferation of the granulocyte-macrophages in bone marrow, and inhibition of the gamma-ray induced suppression of hematopoietic stem cells/hematopoietic progenitor cells. Data thus indicate that prior exposure to microwaves may be beneficial in providing protection against injuries produced by gamma-ray on the hematopoietic system in mice.

  7. Prompt gamma-ray activation analysis (PGAA)

    Energy Technology Data Exchange (ETDEWEB)

    Kern, J. [Fribourg Univ. (Switzerland). Inst. de Physique

    1996-11-01

    The paper deals with a brief description of the principles of prompt gamma-ray activation analysis (PGAA), with the detection of gamma-rays, the PGAA project at SINQ and with the expected performances. 8 figs., 3 tabs., 10 refs.

  8. Gamma ray spectroscopy with PPM resolving power

    CERN Document Server

    Börner, H; Mutti, P

    2002-01-01

    Applications of gamma-ray spectroscopy with ppm resolving power are presented. The extraordinary resolution allows via the Gamma Ray Induced Doppler broadening (GRID) technique to determine lifetimes of excited nuclear levels. This has contributed to important nuclear structure information. We report on the current status of the technique

  9. GAMMA-400 gamma-ray observatory

    CERN Document Server

    Topchiev, N P; Bonvicini, V; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bakaldin, A V; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, L; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Cumani, P; Dalkarov, O D; Dedenko, G L; De Donato, C; Dogiel, V A; Finetti, N; Gascon, D; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Martinez, M; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Paredes, J M; Pearce, M; Picozza, P; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Stozhkov, Yu I; Suchkov, S I; Taraskin, A A; Tavani, M; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Ward, J E; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    The GAMMA-400 gamma-ray telescope with excellent angular and energy resolutions is designed to search for signatures of dark matter in the fluxes of gamma-ray emission and electrons + positrons. Precision investigations of gamma-ray emission from Galactic Center, Crab, Vela, Cygnus, Geminga, and other regions will be performed, as well as diffuse gamma-ray emission, along with measurements of high-energy electron + positron and nuclei fluxes. Furthermore, it will study gamma-ray bursts and gamma-ray emission from the Sun during periods of solar activity. The energy range of GAMMA-400 is expected to be from ~20 MeV up to TeV energies for gamma rays, up to 20 TeV for electrons + positrons, and up to 10E15 eV for cosmic-ray nuclei. For high-energy gamma rays with energy from 10 to 100 GeV, the GAMMA-400 angular resolution improves from 0.1{\\deg} to ~0.01{\\deg} and energy resolution from 3% to ~1%; the proton rejection factor is ~5x10E5. GAMMA-400 will be installed onboard the Russian space observatory.

  10. Gamma-Ray Interactions for Reachback Analysts

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Myers, Steven Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-02

    This presentation is a part of the DHS LSS spectroscopy training course and presents an overview of the following concepts: identification and measurement of gamma rays; use of gamma counts and energies in research. Understanding the basic physics of how gamma rays interact with matter can clarify how certain features in a spectrum were produced.

  11. Handbook on Mobile Gamma-ray Spectrometry

    DEFF Research Database (Denmark)

    Aage, Helle Karina; Korsbech, Uffe C C

    2003-01-01

    Basic physics and mathematics for Airborne and Car-borne Gamma-ray Spectrometry supplemented with practical examples and methods for advanced data processing......Basic physics and mathematics for Airborne and Car-borne Gamma-ray Spectrometry supplemented with practical examples and methods for advanced data processing...

  12. Dosimetric property of mineral extracted from calamari and exposed to gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Cruz-Zaragoza, E.; Roman-Lopez, J.; Cruz, L. Perez; Furetta, C. [Unidad de Irradiacion y Seguridad Radiologica, Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, A.P. 70-543, 04510 Mexico D.F (Mexico); Chiaravalle, E.; Mangiacotti, M.; Marchesani, G. [Centro di Referenza Nazionale per la Ricerca della Radioattivita nel Settore Zootecnico-Veterinario, Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata, Via Manfredonia 20, I-71121 Foggia (Italy)

    2013-07-03

    Dosimetric property of polymineral fraction, quartz mainly, obtained from calamari was investigated. The commercial calamari samples from China and Sud Africa were collected in the markets of Italy. All polymineral debris were extracted and isolated from the whole body of calamari. The surface of the polymineral samples was analyzed by using the Scanning Electron Microscopy (SEM) and their chemical composition was determined using Energy Dispersive Spectroscopy (EDS). The polymineral was exposed to gamma rays ({sup 60}Co) at different doses (0.5-80 Gy) to determine dosimetric property. Thermoluminescent (TL) glow curves showed two peaks centered at around 98-100 Degree-Sign C and 128-138 Degree-Sign C temperature range. The glow curves have been analyzed by using a deconvolution program. A linear dose response between 0.5 to 20 Gy was observed. The TL response of the samples as a function of the time storage, fading, presented a reduction of about 36-40 % at the end of 24 h. The reproducibility of the TL response after ten cycles of irradiation-readout showed an acceptable standard deviation in dosimetry. The polimineral fraction obtained from calamari shows an interesting dosimetric property and it may be useful for dosimetry in gamma radiation field.

  13. Instrumentation for gamma-ray astronomy

    Science.gov (United States)

    Bertsch, David L.; Fichtel, Carl E.; Trombka, Jacob I.

    1988-01-01

    The current status of gamma-ray-telescope technology for ground, airborne, and space observations is surveyed and illustrated with drawings, diagrams, and graphs and tables of typical data. For the low- and medium-energy ranges, consideration is given to detectors and detector cooling systems, background-rejection methods, radiation damage, large-area detectors, gamma-ray imaging, data analysis, and the Compton-interaction region. Also discussed are the gamma-ray interaction process at high energies; multilevel automated spark-chamber gamma-ray telescopes; the Soviet Gamma-1 telescope; the EGRET instrument for the NASA Gamma-Ray Observatory; and Cerenkov, air-shower, and particle-detector instruments for the TeV and PeV ranges. Significant improvements in resolution and sensitivity are predicted for the near future.

  14. Gamma-ray pulsars: a gold mine

    CERN Document Server

    Grenier, Isabelle A

    2015-01-01

    The most energetic neutron stars, powered by their rotation, are capable of producing pulsed radiation from the radio up to gamma rays with nearly TeV energies. These pulsars are part of the universe of energetic and powerful particle accelerators, using their uniquely fast rotation and formidable magnetic fields to accelerate particles to ultra-relativistic speed. The extreme properties of these stars provide an excellent testing ground, beyond Earth experience, for nuclear, gravitational, and quantum-electrodynamical physics. A wealth of gamma-ray pulsars has recently been discovered with the Fermi Gamma-Ray Space Telescope. The energetic gamma rays enable us to probe the magnetospheres of neutron stars and particle acceleration in this exotic environment. We review the latest developments in this field, beginning with a brief overview of the properties and mysteries of rotation-powered pulsars, and then discussing gamma-ray observations and magnetospheric models in more detail.

  15. Investigation of the initial and volume recombination losses in gamma versatile cylindrical ionization chamber VGIC developed for gamma ray dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Fares, M.; Mameri, S.; Abdlani, I.; Negara, K. [COMENA, Laboratoire Detection et Mesures, CRNB, BP no. 180 Ain-Oussera 17200 W. de Djelfa (Algeria)

    2015-07-01

    A versatile Gamma ionization chambers are used for flow control in systems with gamma nuclear reactors and reprocessing plants in and monitoring atmosphere around these facilities, this in order to protect staff. In the Laboratory Detection and Measures (LDM) Division for Study and Development of Nuclear Instrumentation (DSDNI) of CRNB, we designed, developed and characterized a versatile gamma ionization chamber (VGIC) to study experimentally its characteristics according to the geometry of the electrodes, the volume and pressure of the filler gas for the design of a gamma sealed chamber. The tests were conducted under the IEC (International Electro-technical Commission). In this paper, we present the results obtained in the various nuclear tests for characterization and calibration that we have made on the ionization chamber gamma VGIC prototype developed at our Department. To do this, three irradiators were operated at the Laboratory Calibration (SSDL) of the Department of Medical Physics Nuclear Research Center of Algiers (CRNA). Irradiator intensive gamma ({sup 60}Co: 1.25 MeV), one medium intensity gamma ({sup 137}Cs: 0.662 MeV) and 3rd low intensity ({sup 60}Co). Saturation curves and linearity were identified and the operating range and the sensitivity of the chamber have been deducted. The (I,V) characteristics of the chamber filled, with argon gas at 3 bar (0.3 M pa) pressure, for gamma ray irradiator sources were studied. To do so, the chamber was irradiated with gamma rays using different numbers of gamma sources (i.e. Up to 5). The plateau region is reached above 200 V and the detector operating voltage is found to be 600 V. It is observed that in the plateau region the slope is constant with an increase in the exposure rate. The (1/I, 1/V) and (I, l/V{sup 2}) characteristic curves reveal the presence of the initial and volume recombination losses. The volume recombination losses are found to be smaller than the initial recombination losses. Finally

  16. Modeling gamma-ray bursts

    Science.gov (United States)

    Maxham, Amanda

    Discovered serendipitously in the late 1960s, gamma-ray bursts (GRBs) are huge explosions of energy that happen at cosmological distances. They provide a grand physical playground to those who study them, from relativistic effects such as beaming, jets, shocks and blastwaves to radiation mechanisms such as synchrotron radiation to galatic and stellar populations and history. Through the Swift and Fermi space telescopes dedicated to observing GRBs over a wide range of energies (from keV to GeV), combined with accurate pinpointing that allows ground based follow-up observations in the optical, infrared and radio, a rich tapestry of GRB observations has emerged. The general picture is of a mysterious central engine (CE) probably composed of a black hole or neutron star that ejects relativistic shells of matter into intense magnetic fields. These shells collide and combine, releasing energy in "internal shocks" accounting for the prompt emission and flaring we see and the "external shock" or plowing of the first blastwave into the ambient surrounding medium has well-explained the afterglow radiation. We have developed a shell model code to address the question of how X-ray flares are produced within the framework of the internal shock model. The shell model creates randomized GRB explosions from a central engine with multiple shells and follows those shells as they collide, merge and spread, producing prompt emission and X-ray flares. We have also included a blastwave model, which can constrain X-ray flares and explain the origin of high energy (GeV) emission seen by the Fermi telescope. Evidence suggests that gamma-ray prompt emission and X-ray flares share a common origin and that at least some flares can only be explained by long-lasting central engine activity. We pay special attention to the time history of central engine activity, internal shocks, and observed flares. We calculate the gamma-ray (Swift/BAT band) and X-ray (Swift/XRT band) lightcurves for arbitrary

  17. Effects of 60Coirradiation on photosynthetic pigments and gas exchange parameters of the leaves of watermelon%60Co-γ辐射种子对西瓜幼苗叶片光合色素及气体交换参数的影响

    Institute of Scientific and Technical Information of China (English)

    李金霞; 李玉明; 陈菁菁; 韩国君; 陈年来

    2015-01-01

    通过对3类不同质量(包括12个品种)的西瓜干种子进行不同剂量的辐射处理,研究了60Co-γ射线辐射对西瓜幼苗叶片光合色素及气体交换参数的影响.结果表明:60Co-γ射线辐射后,西瓜幼苗叶片叶绿素a和类胡萝卜素的含量随辐射剂量的增加呈现先增大后减小的趋势,叶绿素b的含量随辐射剂量的增加总体呈现出逐渐减小的趋势;气体交换参数Gs、Pn、Tr随着辐射剂量的增加而减小.不同质量西瓜种子对60Co-γ辐射的敏感性表现为大种子材料>小种子材料>中等种子材料;不同种质类型西瓜种子对60Co-γ辐射的敏感性表现为杂交种子品种>常规种子品种.

  18. Prompt gamma-ray imaging for small animals

    Science.gov (United States)

    Xu, Libai

    Small animal imaging is recognized as a powerful discovery tool for small animal modeling of human diseases, which is providing an important clue to complete understanding of disease mechanisms and is helping researchers develop and test new treatments. The current small animal imaging techniques include positron emission tomography (PET), single photon emission tomography (SPECT), computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US). A new imaging modality called prompt gamma-ray imaging (PGI) has been identified and investigated primarily by Monte Carlo simulation. Currently it is suggested for use on small animals. This new technique could greatly enhance and extend the present capabilities of PET and SPECT imaging from ingested radioisotopes to the imaging of selected non-radioactive elements, such as Gd, Cd, Hg, and B, and has the great potential to be used in Neutron Cancer Therapy to monitor neutron distribution and neutron-capture agent distribution. This approach consists of irradiating small animals in the thermal neutron beam of a nuclear reactor to produce prompt gamma rays from the elements in the sample by the radiative capture (n, gamma) reaction. These prompt gamma rays are emitted in energies that are characteristic of each element and they are also produced in characteristic coincident chains. After measuring these prompt gamma rays by surrounding spectrometry array, the distribution of each element of interest in the sample is reconstructed from the mapping of each detected signature gamma ray by either electronic collimations or mechanical collimations. In addition, the transmitted neutrons from the beam can be simultaneously used for very sensitive anatomical imaging, which provides the registration for the elemental distributions obtained from PGI. The primary approach is to use Monte Carlo simulation methods either with the specific purpose code CEARCPG, developed at NC State University or with the general purpose

  19. Low dose rate gamma ray induced loss and data error rate of multimode silica fibre links; Affaiblissement et taux d`erreur de transmission de fibres optiques multimodes soumises a une irradiation gamma a faible debit de dose

    Energy Technology Data Exchange (ETDEWEB)

    Breuze, G.; Fanet, H.; Serre, J. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. d`Electronique et d`Instrumentation Nucleaire; Colas, D.; Garnero, E.; Hamet, T. [Electricite de France (EDF), 77 - Ecuelles (France)

    1993-12-31

    Fiber optics data transmission from numerous multiplexed sensors, is potentially attractive for nuclear plant applications. Multimode silica fiber behaviour during steady state gamma ray exposure is studied as a joint programme between LETI CE/SACLAY and EDF Renardieres: transmitted optical power and bit error rate have been measured on a 100 m optical fiber.

  20. Enact of Glutathione(GSH/GSSG) Contents of Fermented Ginseng on the {gamma}-irradiated Liver of Mice

    Energy Technology Data Exchange (ETDEWEB)

    Ko, In Ho [Dept. of Radiology Technology, Jeju Halla College, Jeju (Korea, Republic of)

    2006-03-15

    The radioprotective effects of white and fermented ginseng on liver damage induced by {sup 60}Co {gamma}-ray were investigated. To one group of ICR male mice were given white(150 mg/kg/day for 7 days, orally) and fermented ginseng(150 mg/kg/day for 7 days, orally) before {sup 60}Co {gamma}--ray irradiation. To another group were irradiated by 5 Gy(1.01 Gy/min) dose of {sup 60}Co {gamma}--ray. Contrast group were given with saline(0.1 mL). The levels of reduced(GSH) and oxidized(GSSG) glutathione in liver tissue were measured. In the fermented(150 mg/kg) and white ginseng(150 mg/kg) groups than irradiation group, the GSH levels were significantly increased, but the GSSG levels were significantly decreased. The ratio of GSSG/total GSH was significantly decreased in the fermented(150 mg/kg) and white ginseng(150 mg/kg) groups than irradiation group. In the fermented(150 mg/kg) groups than white ginseng(150 mg/kg) groups the GSH levels were significantly increased. The radioprotective effects of fermented(150 mg/kg) groups than white ginseng(150 mg/kg) groups were increased.

  1. Gamma-ray Burst Cosmology

    CERN Document Server

    Wang, F Y; Liang, E W

    2015-01-01

    Gamma-ray bursts (GRBs) are the most luminous electromagnetic explosions in the Universe, which emit up to $8.8\\times10^{54}$ erg isotropic equivalent energy in the hard X-ray band. The high luminosity makes them detectable out to the largest distances yet explored in the Universe. GRBs, as bright beacons in the deep Universe, would be the ideal tool to probe the properties of high-redshift universe: including the cosmic expansion and dark energy, star formation rate, the reionization epoch and the metal enrichment history of the Universe. In this article, we review the luminosity correlations of GRBs, and implications for constraining the cosmological parameters and dark energy. Observations show that the progenitors of long GRBs are massive stars. So it is expected that long GRBs are tracers of star formation rate. We also review the high-redshift star formation rate derived from GRBs, and implications for the cosmic reionization history. The afterglows of GRBs generally have broken power-law spectra, so it...

  2. Gamma-ray burst progenitors

    CERN Document Server

    Levan, Andrew; de Grijs, Richard; Langer, Norbert; Xu, Dong; Yoon, Sung-Chul

    2016-01-01

    We review our current understanding of the progenitors of both long and short duration gamma-ray bursts (GRBs). Constraints can be derived from multiple directions, and we use three distinct strands; i) direct observations of GRBs and their host galaxies, ii) parameters derived from modeling, both via population synthesis and direct numerical simulation and iii) our understanding of plausible analog progenitor systems observed in the local Universe. From these joint constraints, we describe the likely routes that can drive massive stars to the creation of long GRBs, and our best estimates of the scenarios that can create compact object binaries which will ultimately form short GRBs, as well as the associated rates of both long and short GRBs. We further discuss how different the progenitors may be in the case of black hole engine or millisecond-magnetar models for the production of GRBs, and how central engines may provide a unifying theme between many classes of extremely luminous transient, from luminous an...

  3. Gamma-Ray Burst Progenitors

    Science.gov (United States)

    Levan, Andrew; Crowther, Paul; de Grijs, Richard; Langer, Norbert; Xu, Dong; Yoon, Sung-Chul

    2016-12-01

    We review our current understanding of the progenitors of both long and short duration gamma-ray bursts (GRBs). Constraints can be derived from multiple directions, and we use three distinct strands; (i) direct observations of GRBs and their host galaxies, (ii) parameters derived from modelling, both via population synthesis and direct numerical simulation and (iii) our understanding of plausible analog progenitor systems observed in the local Universe. From these joint constraints, we describe the likely routes that can drive massive stars to the creation of long GRBs, and our best estimates of the scenarios that can create compact object binaries which will ultimately form short GRBs, as well as the associated rates of both long and short GRBs. We further discuss how different the progenitors may be in the case of black hole engine or millisecond-magnetar models for the production of GRBs, and how central engines may provide a unifying theme between many classes of extremely luminous transient, from luminous and super-luminous supernovae to long and short GRBs.

  4. Gamma-Ray Burst Early Afterglows

    CERN Document Server

    Zhang, B

    2005-01-01

    The successful launch and operation of NASA's Swift Gamma-Ray Burst Explorer open a new era for the multi-wavelength study of the very early afterglow phase of gamma-ray bursts (GRBs). GRB early afterglow information is essential to explore the unknown physical composition of GRB jets, the link between the prompt gamma-ray emission and the afterglow emission, the GRB central engine activity, as well as the immediate GRB environment. Here I review some of the recent theoretical efforts to address these problems and describe how the latest Swift data give answers to these outstanding questions.

  5. Atmospheric Cherenkov Gamma-ray Telescopes

    CERN Document Server

    Holder, Jamie

    2015-01-01

    The stereoscopic imaging atmospheric Cherenkov technique, developed in the 1980s and 1990s, is now used by a number of existing and planned gamma-ray observatories around the world. It provides the most sensitive view of the very high energy gamma-ray sky (above 30 GeV), coupled with relatively good angular and spectral resolution over a wide field-of-view. This Chapter summarizes the details of the technique, including descriptions of the telescope optical systems and cameras, as well as the most common approaches to data analysis and gamma-ray reconstruction.

  6. Effects of γ-ray total body irradiation from a 60Co source on expression level of intrathymic forkhead box protein N1 in mice%60Coγ射线全身照射对小鼠胸腺中叉状头转录因子N1表达水平的影响

    Institute of Scientific and Technical Information of China (English)

    孙玉琦; 武育菁; 刘洁; 潘彬; 徐开林

    2016-01-01

    delta样配体(DLL)4、自身免疫调节蛋白(Aire)与骨形成蛋白(BMP)4 mRNA相对表达水平相比,差异均有统计学意义(CCL25 mRNA相对表达水平:11.2±1.5、11.4±1.2、1.0±0.1,DLL4 mRNA相对表达水平:7.3±0.9、6.3±0.3、1.0±0.1,Aire mRNA相对表达水平:5.1±1.0、5.0±0.1、1.0±0.1,BMP4 mRNA相对表达水平:4.4±1.4、3.6±0.5、1.0±0.1;F=148.862、197.667、73.911、21.471,P=0.000、0.000、0.000、0.000);3组中Foxn1上游基因同源框蛋白(Hox)a3 mRNA相对表达水平相比,差异却无统计学意义(1.4±0.4、0.8±0.3、1.0±0.1相比;F=5.368,P=0.221).与对照组相比,L-TBI 5 d组中Foxn1下游基因CCL25、DLL4与Aire的mRNA相对表达水平均显著增高(p=0.000、0.000、0.000);SL-TBI 5 d组中CCL25、DLL4与Aire mRNA相对表达水平亦显著增高(P=0.000、0.000、0.000).同时,与对照组相比,L-TBI 5 d组、SL-TBI 5 d组中BMP4mRNA相对表达水平存在一定程度的增高,且差异亦有统计学意义(P=0.000、0.000).结论 60C0γ射线TBI可导致小鼠胸腺中Foxn1mRNA表达水平增高,Foxn1表达水平上调及其相关基因表达水平的变化与胸腺受损程度的关系密切.%Objectives To explore the influence of γ-ray total body irradiation (TBI) from a 60Co source induced mice thymus injury on expression levels of forkhead box protein N (Foxn) 1 and related genes,and to analyze the correlation between expression levels of Foxn1,related genes and thymus injury.Methods Sixty five male C57BL/6 mice were chosen as subjects during November and December 2014.Inclusion criteria for choosing mice:all these mice are 6-8 weeks old specific pathogen free (SPF) animals,and weighting between 18.0-21.0 g.Thirty-five mice were randomly devided into 4 groups:① Lethal total body irradiation (L-TBI) 5 d group (n=10),mice received a total dose of 7.5 Gy γ-ray TBI from a 60Co source;② Sublethal total body irradiation (SL-TBI) 5 d group (n=10),mice received a total dose of 5.5 Gy TBI;③SL-TBI 24 d group (n =10),mice

  7. GAMMA-RAY AND X-RAY EMISSION FROM GAMMA-RAY-LOUD BLAZARS

    Institute of Scientific and Technical Information of China (English)

    ZHANG XIONG; ZHAO GANG; XIE GUANG-ZHONG; ZHENG GUANG-SHENG; ZHANG LI

    2001-01-01

    We present a strong correlation of the gamma-ray (above 100 MeV) mean spectral indices aγ and X-ray (1 keV)mean spectral indices cX for 34 gamma-ray-loud blazars (16 BL Lac objects and 18 flat spectrum radio quasars). Astrong correlation is also found between the gamma-ray flux densities F-γ and X-ray flux densities Fx in the low state for 47 blazars (17 BL Lac and 30 flat spectrum radio quasars). Possible correlation on the gamma-ray emission mechanism is discussed. We suggest that the main gamma-ray radiation mechanism is probably the synchrotron process. The gamma-ray emission may be somewhat different from that of BL Lac objects and flat spectrum radio quasars.

  8. Gamma-Ray Astrophysics NSSTC Fermi GBM

    Data.gov (United States)

    National Aeronautics and Space Administration — The Fermi Gamma-Ray Burst Monitor (GBM) is not a pointed or imaging instrument. To determine fluxes for known sources, we measure the change in the count rate...

  9. Supernova remnants and gamma-ray sources

    CERN Document Server

    Torres, D F; Dame, T M; Combi, J A; Butt, Y M; Torres, Diego F.; Romero, Gustavo E.; Dame, Thomas M.; Combi, Jorge A.; Butt, Yousaf M.

    2003-01-01

    A review of the possible relationship between $\\gamma$-ray sources and supernova remnants (SNRs) is presented. Particular emphasis is given to the analysis of the observational status of the problem of cosmic ray acceleration at SNR shock fronts. All positional coincidences between SNRs and unidentified $\\gamma$-ray sources listed in the Third EGRET Catalog at low Galactic latitudes are discussed on a case by case basis. For several coincidences of particular interest, new CO(J=1-0) and radio continuum maps are shown, and the mass content of the SNR surroundings is determined. The contribution to the $\\gamma$-ray flux observed that might come from cosmic ray particles (particularly nuclei) locally accelerated at the SNR shock fronts is evaluated. We discuss the prospects for future research in this field and remark on the possibilities for observations with forthcoming $\\gamma$-ray instruments.

  10. The Science of Nuclear Materials Detection using gamma-ray beams: Nuclear Resonance Fluorescence

    Science.gov (United States)

    Ohgaki, Hideaki

    2014-09-01

    An atomic nucleus is excited by absorption of incident photons with an energy the same as the excitation energy of the level, and subsequently a gamma-ray is emitted as it de-excites. This phenomenon is called Nuclear Resonance Fluorescence and mostly used for studies on Nuclear Physics field. By measuring the NRF gamma-rays, we can identify nuclear species in any materials because the energies of the NRF gamma-rays uniquely depend on the nuclear species. For example, 235U has an excitation level at 1733 keV. If we irradiate a material including 235U with a gamma-ray tuned at this excitation level, the material absorbs the gamma-ray and re-emits another gamma-ray immediately to move back towards the ground state. Therefore we can detect the 235U by measuring the re-emitted (NRF) gamma-rays. Several inspection methods using gamma-rays, which can penetrate a thick shielding have been proposed and examined. Bertozzi and Ledoux have proposed an application of nuclear resonance fluorescence (NRF) by using bremsstrahlung radiations. However the signal-to-noise (SN) ratio of the NRF measurement with the bremsstrahlung radiation is, in general, low. Only a part of the incident photons makes NRF with a narrow resonant band (meV-eV) whereas most of incident radiation is scattered by atomic processes in which the reaction rate is higher than that of NRF by several orders of magnitudes and causes a background. Thus, the NRF with a gamma-ray quasi-monochromatic radiation beam is proposed. The monochromatic gamma-rays are generated by using laser Compton scattering (LCS) of electrons and intense laser photons by putting a collimator to restrict the gamma-ray divergence downstream. The LCS gamma-ray, which is energy-tunable and monochromatic, is an optimum apparatus for NRF measurements We have been conducted NRF experiment for nuclear research, especially with high linear polarized gamma-ray generated by LCS, to survey the distribution of M1 strength in MeV region in LCS

  11. Polarization measurements of proton capture gamma rays

    NARCIS (Netherlands)

    Suffert, M.; Endt, P.M.; Hoogenboom, A.M.

    1959-01-01

    The linear polarization has been measured of eight different gamma rays of widely differing energies (Eγ = 0.8 - 8.0 MeV) emitted at resonances in the 24Mg(p, γ)25Al, 30Si(p, γ)31P, and 32S(p, γ)33Cl reactions. The gamma rays emitted at 90° to the proton beam were Compton scattered in a 2″ NaI scint

  12. Soft gamma rays from heavy WIMPs

    Science.gov (United States)

    Krauss, Manuel Ernst; Opferkuch, Toby; Staub, Florian; Winkler, Martin Wolfgang

    2016-12-01

    We propose an explanation of the galactic center gamma ray excess by supersymmetric WIMPs as heavy as 500 GeV. The lightest neutralino annihilates into vector-like leptons or quarks which cascade decay through intermediate Higgs bosons. Due to the long decay chains, the gamma ray spectrum is much softer than naively expected and peaks at GeV energies. The model predicts correlated diboson and dijet signatures to be tested at the LHC.

  13. The HAWC Gamma-Ray Observatory: Sensitivity to Steady and Transient Sources of Gamma Rays

    CERN Document Server

    Abeysekara, A U; Alvarez, C; Álvarez, J D; Arceo, R; Arteaga-Velázquez, J C; Solares, H A Ayala; Barber, A S; Baughman, B M; Bautista-Elivar, N; Belmont, E; BenZvi, S Y; Berley, D; Rosales, M Bonilla; Braun, J; Caballero-Lopez, R A; Caballero-Mora, K S; Carramiñana, A; Castillo, M; Cotti, U; Cotzomi, J; de la Fuente, E; De León, C; DeYoung, T; Hernandez, R Diaz; Díaz-Vélez, J C; Dingus, B L; DuVernois, M A; Ellsworth, R W; Fernandez, A; Fiorino, D W; Fraija, N; Galindo, A; Garfias, F; González, L X; González, M M; Goodman, J A; Grabski, V; Gussert, M; Hampel-Arias, Z; Hui, C M; Hüntemeyer, P; Imran, A; Iriarte, A; Karn, P; Kieda, D; Kunde, G J; Lara, A; Lauer, R J; Lee, W H; Lennarz, D; Vargas, H León; Linares, E C; Linnemann, J T; Longo, M; Luna-GarcIa, R; Marinelli, A; Martinez, H; Martinez, O; Martínez-Castro, J; Matthews, J A J; Miranda-Romagnoli, P; Moreno, E; Mostafá, M; Nava, J; Nellen, L; Newbold, M; Noriega-Papaqui, R; Oceguera-Becerra, T; Patricelli, B; Pelayo, R; Pérez-Pérez, E G; Pretz, J; Rivière, C; Rosa-González, D; Salazar, H; Salesa, F; Sanchez, F E; Sandoval, A; Santos, E; Schneider, M; Silich, S; Sinnis, G; Smith, A J; Sparks, K; Springer, R W; Taboada, I; Toale, P A; Tollefson, K; Torres, I; Ukwatta, T N; Villaseñor, L; Weisgarber, T; Westerhoff, S; Wisher, I G; Wood, J; Yodh, G B; Younk, P W; Zaborov, D; Zepeda, A; Zhou, H

    2013-01-01

    The High-Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory is designed to record air showers produced by cosmic rays and gamma rays between 100 GeV and 100 TeV. Because of its large field of view and high livetime, HAWC is well-suited to measure gamma rays from extended sources, diffuse emission, and transient sources. We describe the sensitivity of HAWC to emission from the extended Cygnus region as well as other types of galactic diffuse emission; searches for flares from gamma-ray bursts and active galactic nuclei; and the first measurement of the Crab Nebula with HAWC-30.

  14. Zinc oxide nanowire gamma ray detector with high spatiotemporal resolution

    Science.gov (United States)

    Mayo, Daniel C.; Nolen, J. Ryan; Cook, Andrew; Mu, Richard R.; Haglund, Richard F.

    2016-03-01

    Conventional scintillation detectors are typically single crystals of heavy-metal oxides or halides doped with rare-earth ions that record the recombination of electron-hole pairs by photon emission in the visible to ultraviolet. However, the light yields are typically low enough to require photomultiplier detection with the attendant instrumental complications. Here we report initial studies of gamma ray detection by zinc oxide (ZnO) nanowires, grown by vapor-solid deposition. The nanowires grow along the c-axis in a wurtzite structure; they are typically 80 nm in diameter and have lengths of 1- 2 μm. The nanowires are single crystals of high quality, with a photoluminescence (PL) yield from band-edge exciton emission in the ultraviolet that is typically one hundred times larger than the PL yield from defect centers in the visible. Nanowire ensembles were irradiated by 662 keV gamma rays from a Cs-137 source for periods of up to ten hours; gamma rays in this energy range interact by Compton scattering, which in ZnO creates F+ centers that relax to form singly-charged positive oxygen vacancies. Following irradiation, we fit the PL spectra of the visible emission with a sum of Gaussians at the energies of the known defects. We find highly efficient PL from the irradiated area, with a figure of merit approaching 106 photons/s/MeV of deposited energy. Over a period of days, the singly charged O+ vacancies relax to the more stable doubly charged O++ vacancies. However, the overall defect PL returns to pre-irradiation values after about a week, as the vacancies diffuse to the surface of these very thin nanowires, indicating that a self-healing process restores the nanowires to their original state.

  15. Temporal Gene Expression of the Cyanobacterium Arthrospira in Response to Gamma Rays.

    Science.gov (United States)

    Badri, Hanène; Monsieurs, Pieter; Coninx, Ilse; Nauts, Robin; Wattiez, Ruddy; Leys, Natalie

    2015-01-01

    The edible cyanobacterium Arthrospira is resistant to ionising radiation. The cellular mechanisms underlying this radiation resistance are, however, still largely unknown. Therefore, additional molecular analysis was performed to investigate how these cells can escape from, protect against, or repair the radiation damage. Arthrospira cells were shortly exposed to different doses of 60Co gamma rays and the dynamic response was investigated by monitoring its gene expression and cell physiology at different time points after irradiation. The results revealed a fast switch from an active growth state to a kind of 'survival modus' during which the cells put photosynthesis, carbon and nitrogen assimilation on hold and activate pathways for cellular protection, detoxification, and repair. The higher the radiation dose, the more pronounced this global emergency response is expressed. Genes repressed during early response, suggested a reduction of photosystem II and I activity and reduced tricarboxylic acid (TCA) and Calvin-Benson-Bassham (CBB) cycles, combined with an activation of the pentose phosphate pathway (PPP). For reactive oxygen species detoxification and restoration of the redox balance in Arthrospira cells, the results suggested a powerful contribution of the antioxidant molecule glutathione. The repair mechanisms of Arthrospira cells that were immediately switched on, involve mainly proteases for damaged protein removal, single strand DNA repair and restriction modification systems, while recA was not induced. Additionally, the exposed cells showed significant increased expression of arh genes, coding for a novel group of protein of unknown function, also seen in our previous irradiation studies. This observation confirms our hypothesis that arh genes are key elements in radiation resistance of Arthrospira, requiring further investigation. This study provides new insights into phasic response and the cellular pathways involved in the radiation resistance of

  16. Temporal Gene Expression of the Cyanobacterium Arthrospira in Response to Gamma Rays.

    Directory of Open Access Journals (Sweden)

    Hanène Badri

    Full Text Available The edible cyanobacterium Arthrospira is resistant to ionising radiation. The cellular mechanisms underlying this radiation resistance are, however, still largely unknown. Therefore, additional molecular analysis was performed to investigate how these cells can escape from, protect against, or repair the radiation damage. Arthrospira cells were shortly exposed to different doses of 60Co gamma rays and the dynamic response was investigated by monitoring its gene expression and cell physiology at different time points after irradiation. The results revealed a fast switch from an active growth state to a kind of 'survival modus' during which the cells put photosynthesis, carbon and nitrogen assimilation on hold and activate pathways for cellular protection, detoxification, and repair. The higher the radiation dose, the more pronounced this global emergency response is expressed. Genes repressed during early response, suggested a reduction of photosystem II and I activity and reduced tricarboxylic acid (TCA and Calvin-Benson-Bassham (CBB cycles, combined with an activation of the pentose phosphate pathway (PPP. For reactive oxygen species detoxification and restoration of the redox balance in Arthrospira cells, the results suggested a powerful contribution of the antioxidant molecule glutathione. The repair mechanisms of Arthrospira cells that were immediately switched on, involve mainly proteases for damaged protein removal, single strand DNA repair and restriction modification systems, while recA was not induced. Additionally, the exposed cells showed significant increased expression of arh genes, coding for a novel group of protein of unknown function, also seen in our previous irradiation studies. This observation confirms our hypothesis that arh genes are key elements in radiation resistance of Arthrospira, requiring further investigation. This study provides new insights into phasic response and the cellular pathways involved in the radiation

  17. Supernovae and Gamma-Ray Bursts

    Science.gov (United States)

    Livio, Mario; Panagia, Nino; Sahu, Kailash

    2001-07-01

    Participants; Preface; Gamma-ray burst-supernova relation B. Paczynski; Observations of gamma-ray bursts G. Fishman; Fireballs T. Piran; Gamma-ray mechanisms M. Rees; Prompt optical emission from gamma-ray bursts R. Kehoe, C. Akerlof, R. Balsano, S. Barthelmy, J. Bloch, P. Butterworth, D. Casperson, T. Cline, S. Fletcher, F. Frontera, G. Gisler, J. Heise, J. Hills, K. Hurley, B. Lee, S. Marshall, T. McKay, A. Pawl, L. Piro, B. Priedhorsky, J. Szymanski and J. Wren; X-ray afterglows of gamma-ray bursts L. Piro; The first year of optical-IR observations of SN1998bw I. Danziger, T. Augusteijn, J. Brewer, E. Cappellaro, V. Doublier, T. Galama, J. Gonzalez, O. Hainaut, B. Leibundgut, C. Lidman, P. Mazzali, K. Nomoto, F. Patat, J. Spyromilio, M. Turatto, J. Van Paradijs, P. Vreeswijk and J. Walsh; X-ray emission of Supernova 1998bw in the error box of GRB980425 E. Pian; Direct analysis of spectra of type Ic supernovae D. Branch; The interaction of supernovae and gamma-ray bursts with their surroundings R. Chevalier; Magnetars, soft gamma-ray repeaters and gamma-ray bursts A. Harding; Super-luminous supernova remnants Y. -H. Chu, C. -H. Chen and S. -P. Lai; The properties of hypernovae: SNe Ic 1998bw, 1997ef, and SN IIn 1997cy K. Nomoto, P. Mazzali, T. Nakamura, K. Iwanmoto, K. Maeda, T. Suzuki, M. Turatto, I. Danziger and F. Patat; Collapsars, Gamma-Ray Bursts, and Supernovae S. Woosley, A. MacFadyen and A. Heger; Pre-supernova evolution of massive stars N. Panagia and G. Bono; Radio supernovae and GRB 980425 K. Weiler, N. Panagia, R. Sramek, S. Van Dyk, M. Montes and C. Lacey; Models for Ia supernovae and evolutionary effects P. Hoflich and I. Dominguez; Deflagration to detonation A. Khokhlov; Universality in SN Iae and the Phillips relation D. Arnett; Abundances from supernovae F. -K. Thielemann, F. Brachwitz, C. Freiburghaus, S. Rosswog, K. Iwamoto, T. Nakamura, K. Nomoto, H. Umeda, K. Langanke, G. Martinez-Pinedo, D. Dean, W. Hix and M. Strayer; Sne, GRBs, and the

  18. Influence of the irradiation by the {gamma} rays on various factors of immunity; Influence de l'irradiation par les rayons {gamma} sur divers facteurs d'immunite

    Energy Technology Data Exchange (ETDEWEB)

    Gaude, G.; Coursaget, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-07-01

    Exposed animals often present, in the days or weeks following the irradiation, heavy infectious lesions. The goal of this survey was to search the influence of the total irradiation by the gamma radiation from cobalt-60, on the organism, on the phagocytic power of the leukocytes and on the biogenesis of antibodies. The experiences were done on hundred animals, rabbits and guinea pigs. All irradiations have been achieved with eight sources of Cobalt 60 of 10 curies each, disposed on a sphere of 1 m, the animal living the region neighboring of the center. The intensity of the radiation, in these conditions, is about 100 roentgens per hour. (authors) [French] Les animaux irradies presentent souvent, dans les jours ou les semaines qui suivent l'irradiation, de graves lesions infectieuses. Le but de cette etude etait de rechercher l'influence de l'irradiation totale de l'organisme par le rayonnement gamma du cobalt 60 sur le pouvoir phagocytaire des leucocytes et sur la biogenese des anticorps. Les experiences portent sur une centaine d'animaux, lapins et cobayes. Toutes les irradiations ont ete realisees avec huit sources de Cobalt 60 de 10 curies chacune, disposees sur une sphere de 1 m de rayon, les animaux ocoupant la region voisine du centre. L'intensite du rayonnement est, dans ces conditions, d'environ 100 roentgens par heure. (auteurs)

  19. New insights from cosmic gamma rays

    Science.gov (United States)

    Roland, Diehl

    2016-04-01

    The measurement of gamma rays from cosmic sources at ~MeV energies is one of the key tools for nuclear astrophysics, in its study of nuclear reactions and their impacts on objects and phenomena throughout the universe. Gamma rays trace nuclear processes most directly, as they originate from nuclear transitions following radioactive decays or high-energy collisions with excitation of nuclei. Additionally, the unique gamma-ray signature from the annihilation of positrons falls into this astronomical window and is discussed here: Cosmic positrons are often produced from β-decays, thus also of nuclear physics origins. The nuclear reactions leading to radioactive isotopes occur inside stars and stellar explosions, which therefore constitute the main objects of such studies. In recent years, both thermonuclear and core-collapse supernova radioactivities have been measured though 56Ni, 56Co, and 44Ti lines, and a beginning has thus been made to complement conventional supernova observations with such measurements of the prime energy sources of supernova light created in their deep interiors. The diffuse radioactive afterglow of massive-star nucleosynthesis in gamma rays is now being exploited towards astrophysical studies on how massive stars feed back their energy and ejecta into interstellar gas, as part of the cosmic cycle of matter through generations of stars enriching the interstellar gas and stars with metals. Large interstellar cavities and superbubbles have been recognised to be the dominating structures where new massive-star ejecta are injected, from 26Al gamma-ray spectroscopy. Also, constraints on the complex interiors of stars derive from the ratio of 60Fe/26Al gamma rays. Finally, the puzzling bulge-dominated intensity distribution of positron annihilation gamma rays is measured in greater detail, but still not understood; a recent microquasar flare provided evidence that such objects may be prime sources for positrons in interstellar space, rather than

  20. Fermi LAT Discovery of Extended Gamma-Ray Emissions in the Vicinity of the HB3 Supernova Remnant

    CERN Document Server

    Katagiri, H; Ballet, J; Grondin, M H; Hanabata, Y; Hewitt, J W; Kubo, H; Lemoine-Goumard, M

    2016-01-01

    We report the discovery of extended gamma-ray emission measured by the Large Area Telescope (LAT) onboard the Fermi Gamma-ray Space Telescope in the region of the supernova remnant (SNR) HB3 (G132.7+1.3) and the W3 HII complex adjacent to the southeast of the remnant. W3 is spatially associated with bright 12CO (J=1-0) emission. The gamma-ray emission is spatially correlated with this gas and the SNR. We discuss the possibility that gamma rays originate in interactions between particles accelerated in the SNR and interstellar gas or radiation fields. The decay of neutral pions produced in nucleon-nucleon interactions between accelerated hadrons and interstellar gas provides a reasonable explanation for the gamma-ray emission. The emission from W3 is consistent with irradiation of the CO clouds by the cosmic rays accelerated in HB3.

  1. FERMI LAT DISCOVERY OF EXTENDED GAMMA-RAY EMISSIONS IN THE VICINITY OF THE HB 3 SUPERNOVA REMNANT

    Energy Technology Data Exchange (ETDEWEB)

    Katagiri, H.; Yoshida, K. [College of Science, Ibaraki University, 2-1-1, Bunkyo, Mito 310-8512 (Japan); Ballet, J. [Laboratoire AIM, CEA-IRFU/CNRS/Université Paris Diderot, Service d’Astrophysique, CEA Saclay, F-91191 Gif sur Yvette (France); Grondin, M.-H.; Lemoine-Goumard, M. [Centre d’Études Nucléaires de Bordeaux Gradignan, IN2P3/CNRS, Université Bordeaux 1, BP120, F-33175 Gradignan Cedex (France); Hanabata, Y. [Institute for Cosmic-Ray Research, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8582 (Japan); Hewitt, J. W. [Department of Physics and Center for Space Sciences and Technology, University of Maryland Baltimore County, Baltimore, MD 21250 (United States); Kubo, H., E-mail: hideaki.katagiri.sci@vc.ibaraki.ac.jp, E-mail: 13nm169s@gmail.com [Department of Physics, Graduate School of Science, Kyoto University, Kyoto (Japan)

    2016-02-20

    We report the discovery of extended gamma-ray emission measured by the Large Area Telescope (LAT) onboard the Fermi Gamma-ray Space Telescope in the region of the supernova remnant (SNR) HB 3 (G132.7+1.3) and the W3 II complex adjacent to the southeast of the remnant. W3 is spatially associated with bright {sup 12}CO (J = 1–0) emission. The gamma-ray emission is spatially correlated with this gas and the SNR. We discuss the possibility that gamma rays originate in interactions between particles accelerated in the SNR and interstellar gas or radiation fields. The decay of neutral pions produced in nucleon–nucleon interactions between accelerated hadrons and interstellar gas provides a reasonable explanation for the gamma-ray emission. The emission from W3 is consistent with irradiation of the CO clouds by the cosmic rays accelerated in HB 3.

  2. On the difference between gamma-ray-detected and non-gamma-ray-detected pulsars

    CERN Document Server

    Rookyard, Simon C; Johnston, Simon; Kerr, Matthew

    2016-01-01

    We compare radio profile widths of young, energetic gamma-ray-detected and non-gamma-ray-detected pulsars. We find that the latter typically have wider radio profiles, with the boundary between the two samples exhibiting a dependence on the rate of rotational energy loss. We also find that within the sample of gamma-ray-detected pulsars, radio profile width is correlated with both the separation of the main gamma-ray peaks and the presence of narrow gamma-ray components. These findings lead us to propose that these pulsars form a single population where the main factors determining gamma ray detectability are the rate of rotational energy loss and the proximity of the line of sight to the rotation axis. The expected magnetic inclination angle distribution will be different for radio pulsars with and without detectable gamma rays, naturally leading to the observed differences. Our results also suggest that the geometry of existing radio and outer-magnetosphere gamma-ray emission models are at least qualitative...

  3. Gamma-Ray Pulsars Expected in the Outer Gap Model of Gamma-Ray Emission

    Institute of Scientific and Technical Information of China (English)

    张力; 吴杰; 姜泽军; 梅冬成

    2003-01-01

    We study the possibility of high-energy gamma-ray emission from the known 1130 radio pulsars based on the outer gap model of high-energy emission from pulsars. We estimate the fractional size of outer gap, the integrated flux, the gamma-ray luminosity for each known radio pulsar, and find that only 14% of the known radio pulsars are gamma-ray emitters according to the outer gap model. In the sample of possible 156 gamma-ray pulsars, our statistical analysis indicates that the distributions of the spin-down powers and the ages of these pulsars concentrate mainly on 1033.5-1039 erg/s and 103-107 y, respectively. The predictions of gamma-ray pulsars detected by the AGILE and GLAST missions are given.

  4. Gamma-Ray Lenses for Astrophysics-and the Gamma-Ray Imager Mission GRI

    DEFF Research Database (Denmark)

    Wunderer, C. B.; Ballmoos, P. V.; Barriere, N.

    2009-01-01

    Observations of the gamma-ray sky reveal the most powerful sources and the most violent events in the Universe. While at lower wavebands the observed emission is generally dominated by thermal processes, the gamma-ray sky provides us with a view on the non-thermal Universe. Here particles...... are accelerated to extreme relativistic energies by mechanisms which are still poorly understood, and nuclear reactions are synthesizing the basic constituents of our world. Cosmic accelerators and cosmic explosions are major science themes that are addressed in the gamma-ray regime. While Fermi will take......, albeit at much more modest sensitivities. There will be clearly a growing need to perform deeper, more focused investigations of gamma-ray sources in the 100-keV to MeV regime. Recent technological advances in the domain of gamma-ray focusing using Lane diffraction and multilayer-coated mirror techniques...

  5. The Infrared-Gamma-Ray Connection: A WISE View of the Extragalactic Gamma-Ray Sky

    CERN Document Server

    Massaro, F

    2016-01-01

    Using data from the WISE all-sky survey we discovered that the non-thermal infrared (IR) emission of blazars, the largest known population of extragalactic gamma-ray sources, has peculiar spectral properties. In this work, we confirm and strengthen our previous analyses using the latest available releases of both the WISE and the Fermi source catalogs. We also show that there is a tight correlation between the mid-IR colors and the gamma-ray spectral index of Fermi blazars. We name this correlation "the infrared--gamma-ray connection". We discuss how this connection links both the emitted powers and the spectral shapes of particles accelerated in jets arising from blazars over ten decades in energy. Based on this evidence, we argue that the infrared--gamma-ray connection is stronger than the well known radio--gamma-ray connection.

  6. Gamma-Ray Astronomy from the Ground

    CERN Document Server

    Horns, D

    2016-01-01

    The observation of cosmic gamma-rays from the ground is based upon the detection of gamma-ray initiated air showers. At energies between approximately $10^{11}$ eV and $10^{13}$ eV, the imaging air Cherenkov technique is a particularly successful approach to observe gamma-ray sources with energy fluxes as low as $\\approx 10^{-13}$ erg\\,cm$^{-2}\\,$s$^{-1}$. The observations of gamma-rays in this energy band probe particle acceleration in astrophysical plasma conditions and are sensitive to high energy phenomena beyond the standard model of particle physics (e.g., self-annihilating or decaying dark matter, violation of Lorentz invariance, mixing of photons with light pseudo-scalars). The current standing of the field and its major instruments are summarised briefly by presenting selected highlights. A new generation of ground based gamma-ray instruments is currently under development. The perspectives and opportunities of these future facilities will be discussed.

  7. Stellar Photon Archaeology with Gamma-Rays

    Science.gov (United States)

    Stecker, Floyd W.

    2009-01-01

    Ongoing deep surveys of galaxy luminosity distribution functions, spectral energy distributions and backwards evolution models of star formation rates can be used to calculate the past history of intergalactic photon densities and, from them, the present and past optical depth of the Universe to gamma-rays from pair production interactions with these photons. The energy-redshift dependence of the optical depth of the Universe to gamma-rays has become known as the Fazio-Stecker relation (Fazio & Stecker 1970). Stecker, Malkan & Scully have calculated the densities of intergalactic background light (IBL) photons of energies from 0.03 eV to the Lyman limit at 13.6 eV and for 0$ < z < $6, using deep survey galaxy observations from Spitzer, Hubble and GALEX and have consequently predicted spectral absorption features for extragalactic gamma-ray sources. This procedure can also be reversed. Determining the cutoff energies of gamma-ray sources with known redshifts using the recently launched Fermi gamma-ray space telescope may enable a more precise determination of the IBL photon densities in the past, i.e., the "archaeo-IBL.", and therefore allow a better measure of the past history of the total star formation rate, including that from galaxies too faint to be observed.

  8. Interaction studies and gamma-ray properties of some low-Z materials

    Directory of Open Access Journals (Sweden)

    Bhosale Rameshwar R.

    2016-01-01

    Full Text Available In present work we use NaI(Tl detector in narrow-beam good geometry set-up for the gamma ray attenuation studies of some low-Z materials. The parameters such as mass attenuation coefficients, effective atomic numbers and effective electron densities, atomic cross-sections, electronic cross-sections of materials for graphitic powder, polycarbonate, polyvinyl chloride, plaster of Paris, gypsum, and limestone were determined using gamma ray sources 57Co, 133Ba, 137Bs, 60Co, and 22Na at energies of 122, 356, 511, 662, 840, 1170, 1275, and 1330 keV. It was observed that the effective atomic numbers and effective electron densities initially decrease and tend to be almost constant as a function of gamma-ray energy. An attempt was done to check the availability of these low-Z materials at large scales and obtainable at low cost as gamma ray shielding materials. The investigated data are useful in electronic industry, plastic industry, building materials, and agriculture fields.

  9. Raman and AFM study of gamma irradiated plastic bottle sheets

    Science.gov (United States)

    Ali, Yasir; Kumar, Vijay; Sonkawade, R. G.; Dhaliwal, A. S.

    2013-02-01

    In this investigation, the effects of gamma irradiation on the structural properties of plastic bottle sheet are studied. The Plastic sheets were exposed with 1.25MeV 60Co gamma rays source at various dose levels within the range from 0-670 kGy. The induced modifications were followed by micro-Raman and atomic force microscopy (AFM). The Raman spectrum shows the decrease in Raman intensity and formation of unsaturated bonds with an increase in the gamma dose. AFM image displays rough surface morphology after irradiation. The detailed Raman analysis of plastic bottle sheets is presented here, and the results are correlated with the AFM observations.

  10. EPR identification of irradiated Monascus purpureus red pigment

    Energy Technology Data Exchange (ETDEWEB)

    Duliu, Octavian G. E-mail: odlu@scut.fizica.unibuc.ro; Ferdes, Mariana; Ferdes, Ovidiu S

    2000-01-01

    Fresh red alimentary pigment extracted from Monascus purpureus fungus exhibits an intense EPR line consisting of a single, narrow line, attributed to a quinone radical. When irradiated with 7 MeV electrons or {sup 60}Co {gamma}-rays, the amplitude of this line increased with the absorbed dose following a saturation exponential dependency up to 10 kGy. During annealing treatment (isothermal heating at 100 deg. C) the irradiation centers decay exponentially with a half-life time of 2.30 min.

  11. Study of the {sup 60}Co speciation in the aqueous radioactive waste of the la Hague nuclear reprocessing plant; environmental behaviour after discharges in the waters of the channel; Etude de la speciation du {sup 60}Co dans les effluents de l'usine de retraitement de combustibles irradies de la Hague; devenir apres rejet dans les eaux de la Manche

    Energy Technology Data Exchange (ETDEWEB)

    Gaudaire, J.M

    1999-07-01

    {sup 60}Co is produced as an activation product and is present in the low-level aqueous radioactive waste released from the La Hague plant. At present, the concentration in the sea (non filtered at 0.45 {mu}m) at the Goury site are close to or even below, the detection limit: 0.2 mBq.l{sup -1}. The {sup 60}Co speciation depends on the type of effluent considered: in the effluent A ('active'), the cobalt is in the form of a stable trivalent complex; in the effluent V (to be checked), the cobalt is in majority (50% of the activity release) in the form of particles (>0.45 {mu}m), and then in the form of two soluble species: ionic divalent (Co{sup 2+}) and some stable complexes. The evolution of the reprocessing techniques used does not affect the speciation. So, since the nuclear reprocessing plant started at the La Hague plant in 1966, the chemical species discharged in the sea shows time variation related to the evolution of the type of effluent discharged. Thus, since 1994, the particles of cobalt are the main species discharged in the Channel (the V effluents represent more than 85% of the total {sup 60}Co activity released). The effect of instantaneous dilution into the marine conditions involving a variation of pH, oxido-reduction, ionic strength, a gradient of salinity, does not interfere with the evolution of the chemical species discharged. Nevertheless, during the discharge of the V effluent, the main constituents of the sea water (Mg{sup 2+} and Ca{sup 2+}) go through a precipitation. This comes with the coprecipitation of the ion Co{sup 2+} and with the particles of cobalt (complexes are not affected), and it can be responsible for an increase in the concentration in the particles. The chemical behaviour of the cobalt in the Channel is different from those of conservative element such as antimony. The ionic cobalt and the particles have a small dispersion in the water (cobalt has a very high particle/dissolved distribution factor, it is a non

  12. New insights from cosmic gamma rays

    CERN Document Server

    Diehl, Roland

    2016-01-01

    The measurement of gamma rays from cosmic sources at MeV energies is one of the key tools for nuclear astrophysics, in its study of nuclear reactions and their impacts on objects and phenomena throughout the universe. Gamma rays trace nuclear processes most directly, as they originate from nuclear transitions following radioactive decays or high-energy collisions with excitation of nuclei. Additionally, the unique gamma-ray signature from the annihilation of positrons falls into this astronomical window and is discussed here: Cosmic positrons are often produced from beta-decays, thus also of nuclear physics origins. The nuclear reactions leading to radioactive isotopes occur inside stars and stellar explosions, which therefore constitute the main objects of such studies. In recent years, both thermonuclear and core-collapse supernova radioactivities have been measured, and complement conventional supernova observations with measurements of their prime energy sources. The diffuse radioactive afterglow of massi...

  13. Technology Needs for Gamma Ray Astronomy

    Science.gov (United States)

    Gehrels, Neil

    2011-01-01

    Gamma ray astronomy is currently in an exciting period of multiple missions and a wealth of data. Results from INTEGRAL, Fermi, AGILE, Suzaku and Swift are making large contributions to our knowledge of high energy processes in the universe. The advances are due to new detector and imaging technologies. The steps to date have been from scintillators to solid state detectors for sensors and from light buckets to coded aperture masks and pair telescopes for imagers. A key direction for the future is toward focusing telescopes pushing into the hard X-ray regime and Compton telescopes and pair telescopes with fine spatial resolution for medium and high energy gamma rays. These technologies will provide finer imaging of gamma-ray sources. Importantly, they will also enable large steps forward in sensitivity by reducing background.

  14. TeV Gamma-Ray Astrophysics

    CERN Document Server

    Ribó, M

    2008-01-01

    The window of TeV Gamma-Ray Astrophysics was opened less than two decades ago, when the Crab Nebula was detected for the first time. After several years of development, the technique used by imaging atmospheric Cherenkov telescopes like HESS, MAGIC or VERITAS, is now allowing to conduct sensitive observations in the TeV regime. Water Cherenkov instruments like Milagro are also providing the first results after years of integration time. Different types of extragalactic and galactic sources have been detected, showing a variety of interesting phenomena that are boosting theory in very high energy gamma-ray astrophysics. Here I review some of the most interesting results obtained up to now, making special emphasis in the field of X-ray/gamma-ray binaries.

  15. Application of a rapid screening method to detect irradiated meat in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Villavicencio, A.L.C.H. E-mail: villavic@net.ipen.br; Mancini-Filho, J. E-mail: jmancini@usp.br; Delincee, H. E-mail: henrydelincee@bfe.uni-karlsruhe.de

    2000-03-01

    Based on the enormous potential for food irradiation in Brazil, and to ensure free consumer choice, there is a need to find a convenient and rapid method for detection of irradiated food. Since treatment with ionising radiation causes DNA fragmentation, the analysis of DNA damage might be promising. In this paper, the DNA Comet Assay was used to identify exotic meat (boar, jacare and capybara), irradiated with {sup 60}Co gamma rays. The applied radiation doses were 0, 1.5, 3.0 and 4.5 kGy. Analysis of the DNA migration enabled a rapid identification of the radiation treatment.

  16. Application of a rapid screening method to detect irradiated meat in Brazil

    Science.gov (United States)

    Villavicencio, A. L. C. H. A. L. C. H.; Mancini-Filho, J. J.; Delincée, H.

    2000-03-01

    Based on the enormous potential for food irradiation in Brazil, and to ensure free consumer choice, there is a need to find a convenient and rapid method for detection of irradiated food. Since treatment with ionising radiation causes DNA fragmentation, the analysis of DNA damage might be promising. In this paper, the DNA Comet Assay was used to identify exotic meat (boar, jacaré and capybara), irradiated with 60Co gamma rays. The applied radiation doses were 0, 1.5, 3.0 and 4.5 kGy. Analysis of the DNA migration enabled a rapid identification of the radiation treatment.

  17. Suppression of gamma-ray sensitivity of liquid scintillators for neutron detection

    Science.gov (United States)

    Swiderski, L.; Moszyński, M.; Wolski, D.; Iwanowska, J.; Szczęśniak, T.; Schotanus, P.; Hurlbut, C.

    2011-10-01

    Methods to reduce gamma-ray sensitivity of a liquid scintillator EJ309 have been studied. Zero-crossing pulse shape discrimination method was used to separate events generated by neutron and gamma radiation between 60- keVee and 4 MeVee. The measurements were carried out under irradiation from an intense 137Cs source, yielding dose rate of 10 mR/h at the detector. A Pu-Be source was used to establish neutron integration window. Pile-up rejection (PUR) circuit was used to reduce gamma-ray induced events under irradiation from an intense gamma-ray source. Further, application of lead, tin and copper shields was done in order to decrease intrinsic gamma-neutron detection efficiency.

  18. Neutron and Gamma-ray Measurements

    Science.gov (United States)

    Krasilnikov, Anatoly V.; Sasao, Mamiko; Kaschuck, Yuri A.; Kiptily, Vasily G.; Nishitani, Takeo; Popovichev, Sergey V.; Bertalot, Luciano

    2008-03-01

    Due to high neutron and gamma-ray yields and large size plasmas many future fusion reactor plasma parameters such as fusion power, fusion power density, ion temperature, fuel mixture, fast ion energy and spatial distributions can be well measured by various fusion product diagnostics. Neutron diagnostics provide information on fusion reaction rate, which indicates how close is the plasma to the ultimate goal of nuclear fusion and fusion power distribution in the plasma core, which is crucial for optimization of plasma breakeven and burn. Depending on the plasma conditions neutron and gamma-ray diagnostics can provide important information, namely about dynamics of fast ion energy and spatial distributions during neutral beam injection, ion cyclotron heating and generated by fast ions MHD instabilities. The influence of the fast particle population on the 2-D neutron source profile was clearly demonstrated in JET experiments. 2-D neutron and gamma-ray source measurements could be important for driven plasma heating profile optimization in fusion reactors. To meat the measurement requirements in ITER the planned set of neutron and gamma ray diagnostics includes radial and vertical neutron and gamma cameras, neutron flux monitors, neutron activation systems and neutron spectrometers. The necessity of using massive radiation shielding strongly influences the diagnostic designs in fusion reactor, determines angular fields of view of neutron and gamma-ray cameras and spectrometers and gives rise to unavoidable difficulties in the absolute calibration. The development, testing in existing tokomaks and a possible engineering integration of neuron and gamma-ray diagnostic systems into ITER are presented.

  19. EFFECT OF LOW DOSE IRRADIATION OF 60Coγ-RAYS ON SEED GERMINATION, SEEDLING GROWTH AND ENZYMES ACTIVITY OF Lactuca sativa%~(60)Coγ射线低剂量辐照对生菜种子萌发、幼苗生长及酶活性的影响

    Institute of Scientific and Technical Information of China (English)

    刘秀清; 章铁

    2012-01-01

    The seeds of Lactuca sativa were irradiated by different doses (10,20,30,40,50Gy) of 60Co Lactuca sativa ; 60 Co γ-rays ; low dose irradiation ; enzyme activity ; germination- rays. The effects of low dose irradiation on seed germination, seedling growth and enzymes activity were investigated. The results indicated that low dose irradiation could promote germination rate, germinating viability, germination rate in the field, root length and height of seedling. The suitable dosage for low dose irradiation for Lactuca sativa was 30Gy. POD activity after irradiation treatment in the range of 10 to 50Gy and CAT activity after irradiation treatment in the range of 20Gy to 40Gy was lower than that of control.%用不同剂量(10、20、30、40和50Gy)60Coγ射线辐照生菜种子,研究其对种子萌发,幼苗生长和酶活性的影响。结果表明,低剂量辐照可显著提高生菜种子的发芽率、发芽势、田间出苗率、幼苗高度和主根长度,对种子萌发和幼苗生长有一定的促进作用。综合考虑各苗期性状指标初步确定生菜低剂量辐照的适宜剂量为30Gy。在所试剂量范围内辐照处理的POD活性均低于对照;在20~40Gy剂量范围内辐照处理的CAT活性与对照相比也有所降低。

  20. Nuclear forensics using gamma-ray spectroscopy

    CERN Document Server

    Norman, Eric B

    2016-01-01

    Much of George Dracoulis's research career was devoted to utilizing gamma-ray spectroscopy in fundamental studies in nuclear physics. This same technology is useful in a wide range of applications in the area of nuclear forensics. Over the past several years, our research group has made use of both high- and low- resolution gamma ray spectrometers to: identify the first sample of plutonium large enough to be weighed; determine the yield of the Trinity nuclear explosion; measure fission fragment yields as a function of target nucleus and neutron energy; and observe fallout in the U. S. from the Fukushima nuclear reactor accident.

  1. Nuclear Forensics using Gamma-ray Spectroscopy

    Directory of Open Access Journals (Sweden)

    Norman E. B.

    2016-01-01

    Full Text Available Much of George Dracoulis’s research career was devoted to utilising gamma-ray spectroscopy in fundamental studies in nuclear physics. This same technology is useful in a wide range of applications in the area of nuclear forensics. Over the last several years, our research group has made use of both high- and low-resolution gamma-ray spectrometers to: identify the first sample of plutonium large enough to be weighed; determine the yield of the Trinity nuclear explosion; measure fission fragment yields as a function of target nucleus and neutron energy; and observe fallout in the U. S. from the Fukushima nuclear reactor accident.

  2. Gamma Ray Bursts in the HAWC Era

    CERN Document Server

    Mészáros, Peter; Murase, Kohta; Fox, Derek; Gao, He; Senno, Nicholas

    2015-01-01

    Gamma-Ray Bursts are the most energetic explosions in the Universe, and are among the most promising for detecting multiple non-electromagnetic signals, including cosmic rays, high energy neutrinos and gravitational waves. The multi-GeV to TeV gamma-ray range of GRB could have significant contributions from hadronic interactions, mixed with more conventional leptonic contributions. This energy range is important for probing the source physics, including overall energetics, the shock parameters and the Lorentz factor. We discuss some of the latest observational and theoretical developments in the field.

  3. Status of the Milagro $\\gamma$ Ray Observatory

    CERN Document Server

    Atkins, R; Berley, D; Chen, M L; Coyne, D G; Delay, R S; Dingus, B L; Dorfan, D E; Ellsworth, R W; Evans, D; Falcone, A D; Fleysher, L; Fleysher, R; Gisler, G; Goodman, J A; Haines, T J; Hoffman, C M; Hugenberger, S; Kelley, L A; Leonor, I; Macri, J R; McConnell, M; McCullough, J F; McEnery, J E; Miller, R S; Mincer, A I; Morales, M F; Némethy, P; Ryan, J M; Schneider, M; Shen, B; Shoup, A L; Sinnis, G; Smith, A J; Sullivan, G W; Thompson, T N; Tümer, T O; Wang, K; Wascko, M O; Westerhoff, S; Williams, D A; Yang, T; Yodh, G B

    2001-01-01

    The Milagro Gamma Ray Observatory is the world's first large-area water Cherenkov detector capable of continuously monitoring the sky at TeV energies. Located in northern New Mexico, Milagro will perform an all sky survey of the Northern Hemisphere at energies between ~250 GeV and 50 TeV. With a high duty cycle, large detector area (~5000 square meters), and a wide field-of-view (~1 sr), Milagro is uniquely capable of searching for transient and DC sources of high-energy gamma-ray emission. Milagro has been operating since February, 1999. The current status of the Milagro Observatory and initial results will be discussed.

  4. Nuclear Forensics using Gamma-ray Spectroscopy

    Science.gov (United States)

    Norman, E. B.

    2016-09-01

    Much of George Dracoulis's research career was devoted to utilising gamma-ray spectroscopy in fundamental studies in nuclear physics. This same technology is useful in a wide range of applications in the area of nuclear forensics. Over the last several years, our research group has made use of both high- and low-resolution gamma-ray spectrometers to: identify the first sample of plutonium large enough to be weighed; determine the yield of the Trinity nuclear explosion; measure fission fragment yields as a function of target nucleus and neutron energy; and observe fallout in the U. S. from the Fukushima nuclear reactor accident.

  5. Evaluation of The Combined Effects of Hyperthermia, Cobalt-60 Gamma Rays and IUdR on Cultured Glioblastoma Spheroid Cells and Dosimetry Using TLD-100

    Directory of Open Access Journals (Sweden)

    Ali Neshasteh-Riz

    2014-04-01

    Full Text Available Objective: In radiation treatment, the irradiation which is effective enough to control the tumors far exceeds normal-tissues tolerance. Thus to avoid such unfavourable outcomes, some methods sensitizing the tumor cells to radiation are used. Iododeoxyuridine (IUdR is a halogenated thymidine analogue that known to be effective as a radiosensitizer in human cancer therapy. Improving the potential efficacy of radiation therapy after combining to hyperthermia depends on the magnitude of the differential sensitization of the hyperthermic effects or on the differential cytotoxicity of the radiation effects on the tumor cells. In this study, we evaluated the combined effects of IUdR, hyperthermia and gamma rays of 60Co on human glioblastoma spheroids culture. Materials and Methods: In this experimental study,the cultured spheroids with 100μm diameter were treated by 1 μM IUdR, 43˚C hyperthermia for an hour and 2 Gy gamma rays, respectively. The DNA damages induced in cells were compared using alkaline comet assay method, and dosimetry was then performed by TLD-100. Comet scores were calculated as mean ± standard error of mean (SEM using one-way ANOVA. Results:Comparison of DNA damages induced by IUdR and hyperthermia + gamma treatment showed 2.67- and 1.92-fold enhancement, respectively, as compared to the damages induced by radiation alone or radiation combined IUdR. Dosimetry results showed the accurate dose delivered to cells. Conclusion: Analysis of the comet tail moments of spheroids showed that the radiation treatments combined with hyperthermia and IUdR caused significant radiosensitization when compared to related results of irradiation alone or of irradiation with IUdR. These results suggest a potential clinical advantage of combining radiation with hyperthermia and indicate effectiveness of hyperthermia treatment in inducing cytotoxicity of tumor cells.

  6. The characteristics of epoxy resin cured by {gamma}-ray and E-beam

    Energy Technology Data Exchange (ETDEWEB)

    Nho, Y.C. E-mail: ycnho@kaeri.re.kr; Kang, Phil Hyun; Park, Jong Seok

    2004-10-01

    Epoxy resins are widely used as high-performance thermosetting resins for many industrial applications. In this study, the effect of an electron beam (E-beam) and {gamma}-ray irradiation on the curing of epoxy resins was investigated. Diglycidyl ether of bisphenol-A(DGEBA), diglycidyl ether of bisphenol-F(DGEBF) as epoxy resins, triarylsulfonium hexafluoroantimonate(TASHFA), and triarylsulfonium hexafluorophosphate(TASHFP) as initiators were used in this study. The chemical and mechanical characteristics of irradiated epoxy resins were compared after curing of E-beam and {gamma}-ray irradiation up to 50 kGy in N{sub 2} and air atmosphere. We ascertained the effect of oxygen on the radiation curing of epoxy resin. The thermal properties of cured epoxy were investigated using DMA and TGA. Mechanical properties such as flexural strength were measured. The chemical structures of cured epoxy were characterized by FT-NIR. The gel fraction and the stress at yield of epoxy resins irradiated by E-beam and {gamma}-ray in N{sub 2} atmosphere were also compared with those of epoxy resins irradiated by E-beam and {gamma}-ray in air.

  7. Measurements of 60Co in spoons activated by neutrons during the JCO criticality accident at Tokai-mura in 1999.

    Science.gov (United States)

    Gasparro, J; Hult, M; Komura, K; Arnold, D; Holmes, L; Johnston, P N; Laubenstein, M; Neumaier, S; Reyss, J-L; Schillebeeckx, P; Tagziria, H; Van Britsom, G; Vasselli, R

    2004-01-01

    Neutron activated items from the vicinity of the place where the JCO criticality accident occurred have been used to determine the fluence of neutrons around the facility and in nearby residential areas. By using underground laboratories for measuring the activation products, it is possible to extend the study to also cover radionuclides with very low activities from long-lived radionuclides. The present study describes gamma-ray spectrometry measurements undertaken in a range of underground laboratories for the purpose of measuring (60)Co more than 2 years after the criticality event. The measurements show that neutron fluence determined from (60)Co activity is in agreement with previous measurements using the short-lived radionuclides (51)Cr and (59)Fe. Limits on contamination of the samples with (60)Co are evaluated and shown to not greatly affect the utility of neutron fluence determinations using (60)Co activation.

  8. Evaluation of fruit productivity and quality in Hass avocado submitted to {sup 60}Co gamma radiation; Evaluacion de productividad y calidad de fruta en aguacate Hass sometido a radiacion gamma de {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Cruz T, E. De la; Ibanez P, J.; Mijares O, P.; Garcia A, J.M. [Instituto nacional de Investigaciones Nucleares, Departamento de Biologia, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    1999-07-01

    Evaluation of productivity, postharvest behavior and fruit quality was performed on four years Hass avocado trees irradiated with {sup 60} Co gamma rays in doses of 5, 10, 15, 20 and 25 Gy, established in the ''La Labor'' Experimental Center of the Centro de Investigaciones Cientificas y Tecnologias del Aguacate en el Estado de Mexico (CICTAMEX) at Temascaltepec Mexico. Productivity had a significant increase in the dose of 15 Gy being the average number of fruits nearly 400 % more than the control at fruit setting, being such difference reduced at fruit harvesting to 300 %. In regard to postharvest performance, the respiration index (mg CO{sub 2}/kg/hr) did not show significant differences among treatments. Also others variables such as physiological weight losses, texture, maturity pattern, and sensorial tests (color, flavor, aroma, texture) were not different in regard to the control. This mean that radiation has altered productivity but not the quality and postharvest behavior of fruits. (Author)

  9. Relativistic feedback models of terrestrial gamma-ray flashes and gamma-ray glows

    Science.gov (United States)

    Dwyer, J. R.

    2015-12-01

    Relativistic feedback discharges, also known as dark lightning, are capable of explaining many of the observed properties of terrestrial gamma-ray flashes (TGFs) and gamma-ray glows, both created within thunderstorms. During relativistic feedback discharges, the generation of energetic electrons is self-sustained via the production of backward propagating positrons and back-scattered x-rays, resulting in very larges fluxes of energetic radiation. In addition, ionization produces large electric currents that generate LF/VLF radio emissions and eventually discharge the electric field, terminating the gamma-ray production. In this presentation, new relativistic feedback model results will be presented and compared to recent observations.

  10. Gamma-ray bursts at high redshift

    NARCIS (Netherlands)

    R.A.M.J. Wijers

    1999-01-01

    Gamma-ray bursts are much brighter than supernovae, and could therefore possibly probe the Universe to high redshift. The presently established GRB redshifts range from 0.83 to 5, and quite possibly even beyond that. Since most proposed mechanisms for GRB link them closely to deaths of massive stars

  11. Gamma-Ray Telescope and Uncertainty Principle

    Science.gov (United States)

    Shivalingaswamy, T.; Kagali, B. A.

    2012-01-01

    Heisenberg's Uncertainty Principle is one of the important basic principles of quantum mechanics. In most of the books on quantum mechanics, this uncertainty principle is generally illustrated with the help of a gamma ray microscope, wherein neither the image formation criterion nor the lens properties are taken into account. Thus a better…

  12. Gamma-ray emission from nova outbursts

    CERN Document Server

    Hernanz, M

    2013-01-01

    Classical novae produce radioactive nuclei which are emitters of gamma-rays in the MeV range. Some examples are the lines at 478 and 1275 keV (from 7Be and 22Na) and the positron-electron annihilation emission, with the 511 keV line and a continuum. Gamma-ray spectra and light curves are potential unique tools to trace the corresponding isotopes and to give insights on the properties of the expanding envelope. Another possible origin of gamma-rays is the acceleration of particles up to very high energies, so that either neutral pions or inverse Compton processes produce gamma-rays of energies larger than 100 MeV. MeV photons during nova explosions have not been detected yet, although several attempts have been made in the last decades; on the other hand, GeV photons from novae have been detected with the Fermi satellite in V407 Cyg, a nova in a symbiotic binary, where the companion is a red giant with a wind, instead of a main sequence star as in the cataclysmic variables hosting classical novae. Two more nov...

  13. Gamma-Rays from Intergalactic Shocks

    CERN Document Server

    Keshet, U; Loeb, A; Springel, V; Hernquist, L E; Keshet, Uri; Waxman, Eli; Loeb, Abraham; Springel, Volker; Hernquist, Lars

    2003-01-01

    Structure formation in the intergalactic medium (IGM) produces large-scale, collisionless shock waves, where electrons can be accelerated to highly relativistic energies. Such electrons can Compton scatter cosmic microwave background photons up to gamma-ray energies. We study the radiation emitted in this process using a hydrodynamic cosmological simulation of a LCDM universe. The resulting radiation, extending beyond TeV energies, has roughly constant energy flux per decade in photon energy, in agreement with the predictions of Loeb & Waxman (2000). Assuming that a fraction \\xi_e=0.05 of the shock energy is transferred to the relativistic electrons, as inferred from collisionless non-relativistic shocks in the interstellar medium, we find that the radiation energy flux, e^2 (dJ/de) ~ 50-160 eV cm^{-2} s^{-1} sr^{-1}, constitutes ~10% of the extragalactic gamma-ray background flux. The associated gamma-ray point-sources are too faint to account for the ~60 unidentified EGRET gamma-ray sources, but GLAST s...

  14. Gamma ray observations of the solar system

    Science.gov (United States)

    1981-01-01

    Two general categories are discussed concerning the evolution of the solar system: the dualistic view, the planetesimal approach; and the monistic view, the nebular hypothesis. The major points of each view are given and the models that are developed from these views are described. Possible applications of gamma ray astronomical observations to the question of the dynamic evolution of the solar system are discussed.

  15. Gamma Rays From Rotation-Powered Pulsars

    CERN Document Server

    Harding, A K

    2002-01-01

    The seven known gamma-ray pulsars represent a very small fraction of the more than 1000 presently known radio pulsars, yet they can give us valuable information about pulsar particle acceleration and energetics. Although the theory of acceleration and high-energy emission in pulsars has been studied for over 25 years, the origin of the pulsed gamma rays is a question that remains unanswered. Characteristics of the pulsars detected by the Compton Gamma-Ray Observatory could not clearly distinguish between an emission site at the magnetic poles (polar cap models) and emission from the outer magnetosphere (outer gap models). There are also a number of theoretical issues in both type of model which have yet to be resolved. The two types of models make contrasting predictions for the numbers of radio-loud and radio-quiet gamma-ray pulsars and of their spectral characteristics. GLAST will probably detect at least 50 radio-selected pulsars and possibly many more radio-quiet pulsars. With this large sample, it will b...

  16. New shield for gamma-ray spectrometry

    Science.gov (United States)

    Brar, S. S.; Gustafson, P. F.; Nelson, D. M.

    1969-01-01

    Gamma-ray shield that can be evacuated, refilled with a clean gas, and pressurized for exclusion of airborne radioactive contaminants effectively lowers background noise. Under working conditions, repeated evacuation and filling procedures have not adversely affected the sensitivity and resolution of the crystal detector.

  17. Effects of Shielding on Gamma Rays

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-13

    The interaction of gamma rays with matter results in an effect we call attenuation (i.e. ‘shielding’). Attenuation can dramatically alter the appearance of a spectrum. Attenuating materials may actually create features in a spectrum via x-ray fluorescence

  18. Black Hole Accretion in Gamma Ray Bursts

    Directory of Open Access Journals (Sweden)

    Agnieszka Janiuk

    2017-02-01

    Full Text Available We study the structure and evolution of the hyperaccreting disks and outflows in the gamma ray bursts central engines. The torus around a stellar mass black hole is composed of free nucleons, Helium, electron-positron pairs, and is cooled by neutrino emission. Accretion of matter powers the relativistic jets, responsible for the gamma ray prompt emission. The significant number density of neutrons in the disk and outflowing material will cause subsequent formation of heavier nuclei. We study the process of nucleosynthesis and its possible observational consequences. We also apply our scenario to the recent observation of the gravitational wave signal, detected on 14 September 2015 by the two Advanced LIGO detectors, and related to an inspiral and merger of a binary black hole system. A gamma ray burst that could possibly be related with the GW150914 event was observed by the Fermi satellite. It had a duration of about 1 s and appeared about 0.4 s after the gravitational-wave signal. We propose that a collapsing massive star and a black hole in a close binary could lead to the event. The gamma ray burst was powered by a weak neutrino flux produced in the star remnant’s matter. Low spin and kick velocity of the merged black hole are reproduced in our simulations. Coincident gravitational-wave emission originates from the merger of the collapsed core and the companion black hole.

  19. Chandra Imaging of Gamma-Ray Binaries

    CERN Document Server

    Kargaltsev, Oleg; Hare, Jeremy; Pavlov, George G

    2013-01-01

    We review the multiwavelength properties of the few known gamma-ray binaries, focusing on extended emission recently resolved with Chandra. We discuss the implications of these findings for the nature of compact objects and for physical processes operating in these systems.

  20. Gamma-ray Novae: Rare or Nearby?

    CERN Document Server

    Morris, Paul J; Brown, Anthony M; Chadwick, Paula M

    2016-01-01

    Classical Novae were revealed as a surprise source of gamma-rays in Fermi LAT observations. During the first 8 years since the LAT was launched, 6 novae in total have been detected to > 5 sigma in gamma-rays, in contrast to the 69 discovered optically in the same period. We attempt to resolve this discrepancy by assuming all novae are gamma-ray emitters, and assigning peak one-day fluxes based on a flat distribution of the known emitters to a simulated population. To determine optical parameters, the spatial distribution and magnitudes of bulge and disc novae in M31 are scaled to the Milky Way, which we approximate as a disc with a 20 kpc radius and elliptical bulge with semi major axis 3 kpc and axis ratios 2:1 in the xy plane. We approximate Galactic reddening using a double exponential disc with vertical and radial scale heights of r_d = 5 kpc and z_d = 0.2 kpc, and demonstrate that even such a rudimentary model can easily reproduce the observed fraction of gamma-ray novae, implying that these apparently r...

  1. HAWC observatory catches first gamma rays

    Science.gov (United States)

    Frías Villegas, Gabriela

    2013-06-01

    The world's largest and most modern gamma-ray observatory has carried out its first successful observations. Located inside the Pico de Orizaba national park in the Mexican state of Puebla, the High-Altitude Water Cherenkov Observatory (HAWC) is a collaboration between 26 Mexican and US institutions.

  2. Peak efficiency calibration for attenuation corrected cylindrical sources in gamma ray spectrometry by the use of a point source.

    Science.gov (United States)

    Aguiar, Julio C; Galiano, Eduardo; Fernandez, Jorge

    2006-12-01

    A theoretical method of determining the gamma-ray peak efficiency for a cylindrical source, based on a modified expression for point sources is derived. A term for the photon self-attenuation is included in the calculation. The method is valid for any source material as long as the source activity concentration is considered to be homogeneous. Results of this expression are checked against experimental data obtained with (241)Am, (57)Co, (137)Cs, and (60)Co sources.

  3. Peak efficiency calibration for attenuation corrected cylindrical sources in gamma ray spectrometry by the use of a point source

    Energy Technology Data Exchange (ETDEWEB)

    Aguiar, Julio C. [Autoridad Regulatoria Nuclear, Laboratorio de Espectrometria Gamma, Centro Atomico Ezeiza, B1802AYA, Buenos Aires (Argentina); Galiano, Eduardo [Department of Physics, Laurentian University, Sudbury, Ont., P3E 2C6 (Canada)]. E-mail: egalianoriveros@laurentian.ca; Fernandez, Jorge [Autoridad Regulatoria Nuclear, Laboratorio de Espectrometria Gamma, Centro Atomico Ezeiza, B1802AYA, Buenos Aires (Argentina)

    2006-12-15

    A theoretical method of determining the gamma-ray peak efficiency for a cylindrical source, based on a modified expression for point sources is derived. A term for the photon self-attenuation is included in the calculation. The method is valid for any source material as long as the source activity concentration is considered to be homogeneous. Results of this expression are checked against experimental data obtained with {sup 241}Am, {sup 57}Co, {sup 137}Cs, and {sup 60}Co sources.

  4. $\\gamma$-Ray Absorption at High Redshifts and the $\\gamma$-Ray Background

    CERN Document Server

    Stecker, F W

    1997-01-01

    We present results of a calculation of absorption of 10-500 GeV gamma-rays at high redshifts. This calculation requires the determination of the high- redshift evolution of the full spectral energy distribution of the intergalactic photon field. For this, we have primarily followed the recent analysis of Fall, Charlot and Pei. We give our results for the gamma-ray opacity as a function of redshift out to a redshift of 3. We then give predicted gamma-ray spectra for selected blazars and also extend our results on the background from unresolved blazars to an energy of 500 GeV. Absorption effects are predicted to significantly steepen the background spectrum above 20 GeV. Our absorption calculations can be used to place limits on the redshifts of gamma-ray bursts. Our background calculations can be used to determine the observability of multi-GeV lines from dark matter neutralino particles.

  5. Systematic Study of Gamma-ray bright Blazars with Optical Polarization and Gamma-ray Variability

    CERN Document Server

    Itoh, Ryosuke; Fukazawa, Yasushi; Uemura, Makoto; Tanaka, Yasuyuki T; Kawabata, Koji S; Madejski, Grzegorz M; Schinzel, Frank K; Kanda, Yuka; Shiki, Kensei; Akitaya, Hiroshi; Kawabata, Miho; Moritani, Yuki; Nakaoka, Tatsuya; Ohsugi, Takashi; Sasada, Mahito; Takaki, Katsutoshi; Takata, Koji; Ui, Takahiro; Yamanaka, Masayuki; Yoshida, Michitoshi

    2016-01-01

    Blazars are highly variable active galactic nuclei which emit radiation at all wavelengths from radio to gamma-rays. Polarized radiation from blazars is one key piece of evidence for synchrotron radiation at low energies and it also varies dramatically. The polarization of blazars is of interest for understanding the origin, confinement, and propagation of jets. However, even though numerous measurements have been performed, the mechanisms behind jet creation, composition and variability are still debated. We performed simultaneous gamma-ray and optical photopolarimetry observations of 45 blazars between Jul. 2008 and Dec. 2014 to investigate the mechanisms of variability and search for a basic relation between the several subclasses of blazars. We identify a correlation between the maximum degree of optical linear polarization and the gamma-ray luminosity or the ratio of gamma-ray to optical fluxes. Since the maximum polarization degree depends on the condition of the magnetic field (chaotic or ordered), thi...

  6. Gamma ray spectroscopy in astrophysics: Solar gamma ray astronomy on solar maximum mission. [experimental design

    Science.gov (United States)

    Forrest, D. J.

    1978-01-01

    The SMM gamma ray experiment and the important scientific capabilities of the instrument are discussed. The flare size detectable as a function of spectrum integration time was studied. A preliminary estimate indicates that a solar gamma ray line at 4.4 MeV one-fifth the intensity of that believed to have been emitted on 4 August 1972 can be detected in approximately 1000 sec with a confidence level of 99%.

  7. Teratogenic effect of Californium-252 irradiation in rats

    Energy Technology Data Exchange (ETDEWEB)

    Satow, Yukio; Lee, Juing-Yi; Hori, Hiroshi; Okuda, Hiroe; Tsuchimoto, Shigeo; Sawada, Shozo; Yokoro, Kenjiro (Hiroshima Univ. (Japan). Research Inst. for Nuclear Medicine and Biology)

    1989-06-01

    The teratogenicity of Californium-252 (Cf-252) irradiation which generates approximately 70% 2.3 MeV fast neutron and 30% gamma rays was evaluated. A single whole body exposure of Cf-252 at various doses was given to pregnant rats on day 8 or 9 of pregnancy, followed by microscopic autopsy of the fetuses at the terminal stage of pregnancy to search for external and internal malformations. For comparison, pregnant rats were irradiated with various doses of Cobalt-60 (Co-60) standard gamma rays at the same dose rate (1 rad/min.). The doses were 20-120 rad of Cf-252 and 80-220 rad of Co-60. Using frequency of radiation induced malformations observed on day 8 of pregnancy as an index, relative biological effectiveness (RBE) of 2.3-2.7 was obtained from the straight line obtained by modifying by the least squares method the frequency curves of malformed fetuses in total implants and in surviving fetuses. The types of malformations induced by Cf-252 and Co-60 irradiation were alike. Using fetal LD/sub 50/ as an index, 2.4 was obtained as RBE when irradiated on day 8 of pregnancy and 3.1 as that when irradiated on day 9. The results showed that Cf-252 had stronger a teratogenic effect than Co-60 gamma rays. (author).

  8. Development of a Small-Sized, Flexible, and Insertable Fiber-Optic Radiation Sensor for Gamma-Ray Spectroscopy

    Directory of Open Access Journals (Sweden)

    Wook Jae Yoo

    2015-08-01

    Full Text Available We fabricated a small-sized, flexible, and insertable fiber-optic radiation sensor (FORS that is composed of a sensing probe, a plastic optical fiber (POF, a photomultiplier tube (PMT-amplifier system, and a multichannel analyzer (MCA to obtain the energy spectra of radioactive isotopes. As an inorganic scintillator for gamma-ray spectroscopy, a cerium-doped lutetium yttrium orthosilicate (LYSO:Ce crystal was used and two solid-disc type radioactive isotopes with the same dimensions, cesium-137 (Cs-137 and cobalt-60 (Co-60, were used as gamma-ray emitters. We first determined the length of the LYSO:Ce crystal considering the absorption of charged particle energy and measured the gamma-ray energy spectra using the FORS. The experimental results demonstrated that the proposed FORS can be used to discriminate species of radioactive isotopes by measuring their inherent energy spectra, even when gamma-ray emitters are mixed. The relationship between the measured photon counts of the FORS and the radioactivity of Cs-137 was subsequently obtained. The amount of scintillating light generated from the FORS increased by increasing the radioactivity of Cs-137. Finally, the performance of the fabricated FORS according to the length and diameter of the POF was also evaluated. Based on the results of this study, it is anticipated that a novel FORS can be developed to accurately measure the gamma-ray energy spectrum in inaccessible locations such as narrow areas and holes.

  9. Trials to identify irradiated chestnut (Castanea bungena) with different analytical techniques

    Energy Technology Data Exchange (ETDEWEB)

    Chung, H.-W. E-mail: chunghw@kfda.go.kr; Delincee, Henry; Han, S.-B.; Hong, J.-H.; Kim, H.-Y.; Kim, M.-C.; Byun, M.-W.; Kwon, J.-H

    2004-10-01

    Photostimulated luminescence (PSL) measurement, DNA comet assay, electron spin resonance (ESR) spectroscopy and thermoluminescence (TL) measurement were applied to identify irradiated chestnut. Samples were irradiated with {sup 60}Co {gamma}-rays at 0-0.5 kGy. The PSL photon counts for irradiated chestnuts were too low to be distinguished from those of the non-irradiated sample. There was no difference in DNA comets between non-irradiated and irradiated chestnuts. ESR spectroscopy did not show any radiation-induced specific signals but a symmetric singlet. However, using TL, the shape of the glow curve (Glow 1) made it possible to identify the irradiated chestnuts. In addition, the TL glow ratio (Glow 1/Glow 2) obtained by normalization was less than 0.01 for the non-irradiated sample and {>=}0.10 for irradiated ones, respectively.

  10. Gamma-Ray Telescopes: 400 Years of Astronomical Telescopes

    Science.gov (United States)

    Gehrels, Neil; Cannizzo, John K.

    2010-01-01

    The last half-century has seen dramatic developments in gamma-ray telescopes, from their initial conception and development through to their blossoming into full maturity as a potent research tool in astronomy. Gamma-ray telescopes are leading research in diverse areas such as gamma-ray bursts, blazars, Galactic transients, and the Galactic distribution of Al-26.

  11. NEW GAMMA RAYS FROM DECAY OF 189W

    Institute of Scientific and Technical Information of China (English)

    杨维凡; 赵之正; 等

    1995-01-01

    Radioactivities of 189W are produced through an 192Os(n,α189W reaction.Gamma ray spectroscopy from chemically separated tungsten sources using HPGe detector has revealed the presence of 22 gamma rays assigned to the decay of 189W,of them,18 gamma rays are new ones unreported until now.

  12. BL Lacertae Objects and the Extragalactic Gamma-Ray Background

    CERN Document Server

    Li, Fan

    2011-01-01

    A tight correlation between gamma-ray and radio emission is found for a sample of BL Lacertae (BL Lac) objects detected by Fermi Gamma-ray Space Telescope (Fermi) and the Energetic Gamma-Ray Experiment Telescope (EGRET). The gamma-ray emission of BL Lac objects exhibits strong variability, and the detection rate of gamma-ray BL Lac objects is low, which may be related to the gamma-ray duty cycle of BL Lac objects. We estimate the gamma-ray duty cycle ~ 0.11, for BL Lac objects detected by EGRET and Fermi. Using the empirical relation of gamma-ray emission with radio emission and the estimated gamma-ray duty cycle, we derive the gamma-ray luminosity function (LF) of BL Lac objects from their radio LF. Our derived gamma-ray LF of BL Lac objects can almost reproduce that calculated with the recently released Fermi bright active galactic nuclei (AGN) sample. We find that about 45% of the extragalactic diffuse gamma-ray background (EGRB) is contributed by BL Lac objects. Combining the estimate of the quasar contri...

  13. Study of the effect of gamma irradiation ({sup 60} Co) on the quality of sugar cane spirit and on the cask of maturation; Estudo do efeito da irradiacao gamma ({sup 60} Co) na qualidade da cachaca e no tonel de envelhecimento

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, Mariana Branco de; Horii, Jorge; Alcarde, Andre Ricardo [Universidade de Sao Paulo (USP), Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Dept.de Agroindustria, Alimentos e Nutricao]. E-mails: jhorii@esalq.usp.br; aralcard@esalq.usp.br

    2006-10-15

    The ageing or maturing process of drink improves the sensorial characteristics of the product making it a qualified drink with higher economical value. The traditional maturing method of drinks involves their interaction with wood and irradiation can accelerate this ageing process. Sugar cane spirit and oak barrels with a 20 L capacity were treated using gamma irradiation (150 Gy). Physical-chemical and chromatographic analyses were constantly performed for 390 days during the drink ageing period. The sugar cane spirit and barrel irradiation did not change most volatile components of the same type coefficient such as volatile acidity, esters, superior alcohols and furfural throughout the 390 days. There is evidence, however, that some component parameters like aldehydes, tannin, color and copper concentration are in some way influenced resulting in partial acceleration of the ageing or maturing process. At the end of the ageing period, a sensorial analysis was made using 30 non-trained people who tasted the drink. The ageing process acceleration was confirmed by the sensorial evaluation, where the irradiated sugar cane spirit and/or barrel had higher approval regarding all parameters analyzed (scent, flavor and appearance). (author)

  14. AD 775 Pulse of Cosmogenic Radionuclides Production as Imprint of a Galactic Gamma-Ray Burst

    CERN Document Server

    Pavlov, A K; Konstantinov, A N; Ostryakov, V M; Vasilyev, G I; Vdovina, M A; Volkov, P A

    2013-01-01

    We suggest an explanation of a sharp increase in the abundance of cosmogenic radiocarbon found in tree rings dated AD 775. The increase could originate from high-energy irradiation of the atmosphere by a galactic gamma-ray burst. We argue that, unlike a cosmic ray event, a gamma-ray burst does not necessarily result in a substantial increase in long-lived 10Be atmospheric production. At the same time, the 36Cl nuclide would be generated in the amounts detectable in the corresponding ice core samples from Greenland and Antarctica. These peculiar features allow experimental discrimination of nuclide effects caused by gamma-ray bursts and by powerful proton events.

  15. Resonance capture gamma-ray spectrometry at Lead Slowing-down Neutron Spectrometer

    CERN Document Server

    Pourimani, R; Popov, Y P; Przytula, M; Wojtkiewicz, R

    2002-01-01

    A new method of measurement of the gamma-ray spectra from resonance neutron capture that can be realized at Lead Slowing-down Neutron Spectrometers was proposed and tested experimentally. The specific feature of the method is the shielding of germanium detector by a 'thick' investigated sample that absorbs intensive neutron flux with energies corresponding to sample resonances. In these energy regions the detector response on neutron irradiation is considerably reduced while the sample gamma-ray spectra are greatly strengthened. The detector response gamma-ray spectra are presented and analysed, and the spectra from neutron capture in tantalum resonances at energies 4.28 and 10.36 eV are shown. The obtained results demonstrate the usefulness of the proposed method. Five new excited levels in germanium isotopes are proposed.

  16. Photoneutron cross sections measurements in {sup 13}C with thermal neutron capture gamma-rays

    Energy Technology Data Exchange (ETDEWEB)

    Semmler, Renato; Carbonari, Artur W.; Terremoto, Luis A.A. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mails: rsemmler@ipen.br; carbonar@ipen.br; laaterre@ipen.br; Goncalez, Odair L. [Centro Tecnico Aeroespacial (CTA-IEAv), Sao Jose dos Campos, SP (Brazil). Inst. de Estudos Avancados]. E-mail: odairl@ieav.cta.br

    2007-07-01

    Photoneutrons cross sections measurements of {sup 13}C have been obtained in energy interval between 5,3 and 10,8 MeV, using neutron capture gamma-rays with high resolution in energy (3 - 21 eV), produced by 21 target materials, placed inside a tangential beam port, near the core of the IPEN/CNEN-SP IEA-R1 (2MW) research reactor. The sample have been irradiated inside a 4p geometry neutron detector system 'Long Counter', 520,5 cm away from the capture target. The capture gamma-ray flux was determined by means of the analysis of the gamma spectrum obtained by using a Ge(Li) solid-state detector (EG and G ORTEC, 25 cm{sup 3}, 5%), previously calibrated with capture gamma-rays from a standard target of Nitrogen (Melamine). The neutron photoproduction cross section has been measured for each target capture gamma-ray spectrum (compound cross section). A methodology for unfolding the set of experimental compound cross sections, have been used in order to obtain the cross sections at specific excitation energy values (principal gamma lines energies of the capture targets). The cross sections were compared with experimental data, reported by other authors, using different gamma-ray sources. A good agreement was observed between in this work and reported in the literature. (author)

  17. Optical properties of CsI single crystals irradiated with neutrons at low temperature

    Energy Technology Data Exchange (ETDEWEB)

    Okada, M. [Kyoto Univ., Kumatori, Osaka (Japan). Research Reactor Inst.; Nakagawa, M. [Faculty of Education, Kagawa Univ., Takamatsu, Kagawa (Japan); Atobe, K. [Faculty of Science, Naruto Univ. of Education, Naruto, Tokushima (Japan); Itatani, N.; Ozawa, K. [Horiba Ltd., Minamiku, Kyoto (Japan)

    1998-05-01

    Optical properties of the irradiation-induced-defects in neutron-irradiated CsI single crystals have been investigated. The nominally pure CsI crystals are irradiated by reactor fast neutrons (E>0.1 MeV) with a fluence of 1.4 x 10{sup 15} n/cm{sup 2} at 20 K and by {gamma}-rays from {sup 60}Co source to a dose of 1.5 x 10{sup 4} Gy at liquid nitrogen temperature (LNT). After the irradiations, isochronal annealings are performed to investigate the thermal behavior of the defects. The glow peaks of the thermoluminescence (TL) in each sample irradiated with neutrons at 20 K and with {gamma}-rays at LNT are observed at about 100, 160 and 220 K. In the neutron-irradiated samples at 20 K, the emission band at 338 nm is observed at LNT. It is supposed that this emission band occurs by an excitation of {gamma}-rays from {sup 134}Cs, which is radioactivated by thermal neutrons among the reactor radiations. It is confirmed that the temperature dependence of the 338 nm band is similar with that of the emission band due to the self-trapped exciton which is introduced into the non-irradiated samples illuminated by higher energy photons. (orig.) 13 refs.

  18. Gamma-Ray Library and Uncertainty Analysis: Passively Emitted Gamma Rays Used in Safeguards Technology

    Energy Technology Data Exchange (ETDEWEB)

    Parker, W

    2009-09-18

    Non-destructive gamma-ray analysis is a fundamental part of nuclear safeguards, including nuclear energy safeguards technology. Developing safeguards capabilities for nuclear energy will certainly benefit from the advanced use of gamma-ray spectroscopy as well as the ability to model various reactor scenarios. There is currently a wide variety of nuclear data that could be used in computer modeling and gamma-ray spectroscopy analysis. The data can be discrepant (with varying uncertainties), and it may difficult for a modeler or software developer to determine the best nuclear data set for a particular situation. To use gamma-ray spectroscopy to determine the relative isotopic composition of nuclear materials, the gamma-ray energies and the branching ratios or intensities of the gamma-rays emitted from the nuclides in the material must be well known. A variety of computer simulation codes will be used during the development of the nuclear energy safeguards, and, to compare the results of various codes, it will be essential to have all the {gamma}-ray libraries agree. Assessing our nuclear data needs allows us to create a prioritized list of desired measurements, and provides uncertainties for energies and especially for branching intensities. Of interest are actinides, fission products, and activation products, and most particularly mixtures of all of these radioactive isotopes, including mixtures of actinides and other products. Recent work includes the development of new detectors with increased energy resolution, and studies of gamma-rays and their lines used in simulation codes. Because new detectors are being developed, there is an increased need for well known nuclear data for radioactive isotopes of some elements. Safeguards technology should take advantage of all types of gamma-ray detectors, including new super cooled detectors, germanium detectors and cadmium zinc telluride detectors. Mixed isotopes, particularly mixed actinides found in nuclear reactor

  19. TeV gamma-ray astronomy

    Institute of Scientific and Technical Information of China (English)

    Wei Cui

    2009-01-01

    The field of ground-based gamma-ray astronomy has enjoyed rapid growth in recent years. As an increasing number of sources are detected at TeV energies, the field has matured and become a viable branch of modern astronomy. Lying at the uppermost end of the electromagnetic rainbow, TeV photons are always preciously few in number but carry essential information about the particle acceleration and radiative processes involved in extreme astronomical settings. Together with observations at longer wavelengths, TeV gamma-ray observations have drastically improved our view of the universe. In this re-view, we briefly describe recent progress in the field. We will conclude by providing a personal perspective on the future of the field, in particular, on the significant roles that China could play in advancing this young but exciting field.

  20. Are gamma-ray bursts cosmological?

    CERN Document Server

    Horvath, I

    2015-01-01

    Gamma-ray burst sources are distributed with a high level of isotropy, which is compatible with either a cosmological origin or an extended Galactic halo origin. The brightness distribution is another indicator used to characterize the spatial distribution in distance. In this paper the author discusses detailed fits of the BATSE gamma-ray burst peak-flux distributions with Friedmann models taking into account possible density evolution and standard candle luminosity functions. A chi-square analysis is used to estimate the goodness of the fits and the author derives the significance level of limits on the density evolution and luminosity function parameters. Cosmological models provide a good fit over a range of parameter space which is physically reasonable

  1. The future of gamma-ray astronomy

    CERN Document Server

    Knödlseder, Jürgen

    2016-01-01

    The field of gamma-ray astronomy has experienced impressive progress over the last decade. Thanks to the advent of a new generation of imaging air Cherenkov telescopes (H.E.S.S., MAGIC, VERITAS) and thanks to the launch of the Fermi-LAT satellite, several thousand gamma-ray sources are known today, revealing an unexpected ubiquity of particle acceleration processes in the Universe. Major scientific challenges are still ahead, such as the identification of the nature of Dark Matter, the discovery and understanding of the sources of cosmic rays, or the comprehension of the particle acceleration processes that are at work in the various objects. This paper presents some of the instruments and mission concepts that will address these challenges over the next decades.

  2. Stirling Colgate and Gamma-Ray Bursts

    Science.gov (United States)

    Lamb, Donald

    2014-10-01

    Even before the discovery of gamma-ray bursts (GRBs), Stirling Colgate proposed that bursts of x rays and gamma rays might be produced by a relativistic shock created in the supernova explosion of a massive star. We trace the scientific story of GRBs from their detection to the present, highlighting along the way Stirling's interest in them and his efforts to understand them. We summarize our current understanding that short, soft, repeating bursts are produced by magnetic neutron stars; short, hard bursts are produced by the mergers of neutron star-neutron star binaries; and long, hard bursts are produced by the core collapse of massive stars that have lost their hydrogen and helium envelopes. We then discuss some important open questions about GRBs and how they might be answered. We conclude by describing the recent serendipitous discovery of an x-ray burst of exactly the kind he proposed, and the insights into core collapse supernovae and GRBs that it provided.

  3. The future of gamma-ray astronomy

    Science.gov (United States)

    Knödlseder, Jürgen

    2016-06-01

    The field of gamma-ray astronomy has experienced impressive progress over the last decade. Thanks to the advent of a new generation of imaging air Cherenkov telescopes (H.E.S.S., MAGIC, VERITAS) and thanks to the launch of the Fermi-LAT satellite, several thousand gamma-ray sources are known today, revealing an unexpected ubiquity of particle acceleration processes in the Universe. Major scientific challenges are still ahead, such as the identification of the nature of Dark Matter, the discovery and understanding of the sources of cosmic rays, or the comprehension of the particle acceleration processes that are at work in the various objects. This paper presents some of the instruments and mission concepts that will address these challenges over the next decades. xml:lang="fr"

  4. Stellar Photon Archaeology with Gamma-Rays

    Science.gov (United States)

    Stecker, Floyd W.

    2009-01-01

    Ongoing deep surveys of galaxy luminosity distribution functions, spectral energy distributions and backwards evolution models of star formation rates can be used to calculate the past history of intergalactic photon densities and, from them, the present and past optical depth of the Universe to gamma-rays from pair production interactions with these photons. The energy-redshift dependence of the optical depth of the Universe to gamma-rays has become known as the Fazio-Stecker relation (Fazio & Stecker 1970). Stecker, Malkan & Scully have calculated the densities of intergalactic background light (IBL) photons of energies from 0.03 eV to the Lyman limit at 13.6 eV and for 0$ photon densities in the past, i.e., the "archaeo-IBL.", and therefore allow a better measure of the past history of the total star formation rate, including that from galaxies too faint to be observed.

  5. Physics of gamma-ray bursts

    Science.gov (United States)

    Lamb, D. Q.

    1984-01-01

    Attention is given to the accumulating evidence for the view that gamma-ray bursts come from strongly magnetic neutron stars, discussing the physical properties of the emission region and the radiation processes expected in strong magnetic fields, and emphasizing that the observed burst spectra require that the emission region be optically thin. This entails that the energy of the emitting plasma and/or the plasma itself be continuously replenished during a burst, and that the cooling time scale of the emitting plasma be much shorter than the observed duration of the bursts. This characteristic of the cooling time scale implies that the burst intensity and spectrum can vary on extremely short time scales, and that the burst duration must have a separate explanation. It is emphasized that synchrotron emission is favored as the gamma-ray production mechanism; it is the only mechanism capable of satisfying the optical thinness constraint while producing the observed luminosity.

  6. TeV Gamma Ray Astronomy

    CERN Document Server

    Cui, Wei

    2009-01-01

    The field of ground-based gamma ray astronomy has enjoyed rapid growth in recent years. As an increasing number of sources are detected at TeV energies, the field has matured and become a viable branch of modern astronomy. Lying at the uppermost end of the electromagnetic rainbow, TeV photons are always preciously few in number but carry essential information about the particle acceleration and radiative processes involved in extreme astronomical settings. Together with observations at longer wavelengths, TeV gamma-ray observations have drastically improved our view of the universe. In this review, we briefly describe recent progress in the field. We will conclude by providing a personal perspective on the future of the field, in particular, on the significant roles that China could play to advance this young but exciting field.

  7. The Future of Gamma Ray Astrophysics

    CERN Document Server

    CERN. Geneva

    2016-01-01

    Over the past decade, gamma ray astrophysics has entered the astrophysical mainstream. Extremely successful space-borne (GeV) and ground-based (TeV) detectors, combined with a multitude of partner telescopes, have revealed a fascinating “astroscape" of active galactic nuclei, pulsars, gamma ray bursts, supernova remnants, binary stars, star-forming galaxies, novae much more, exhibiting major pathways along which large energy releases can flow. From  a basic physics perspective, exquisitely sensitive measurements have constrained the nature of dark matter, the cosmological origin of magnetic field and the properties of black holes. These advances have motivated the development of new facilities, including HAWC, DAMPE, CTA and SVOM, which will further our understanding of the high energy universe. Topics that will receive special attention include merging neutron star binaries, clusters of galaxies, galactic cosmic rays and putative, TeV dark matter.

  8. Real time gamma-ray signature identifier

    Science.gov (United States)

    Rowland, Mark [Alamo, CA; Gosnell, Tom B [Moraga, CA; Ham, Cheryl [Livermore, CA; Perkins, Dwight [Livermore, CA; Wong, James [Dublin, CA

    2012-05-15

    A real time gamma-ray signature/source identification method and system using principal components analysis (PCA) for transforming and substantially reducing one or more comprehensive spectral libraries of nuclear materials types and configurations into a corresponding concise representation/signature(s) representing and indexing each individual predetermined spectrum in principal component (PC) space, wherein an unknown gamma-ray signature may be compared against the representative signature to find a match or at least characterize the unknown signature from among all the entries in the library with a single regression or simple projection into the PC space, so as to substantially reduce processing time and computing resources and enable real-time characterization and/or identification.

  9. Do Gamma-Ray Burst Sources Repeat?

    OpenAIRE

    Meegan, Charles A.; Hartmann, Dieter H.; Brainerd, J. J.; Briggs, Michael S.; Paciesas, William S.; Pendleton, Geoffrey; Kouveliotou, Chryssa; Fishman, Gerald; Blumenthal, George; Brock, Martin

    1995-01-01

    The demonstration of repeated gamma-ray bursts from an individual source would severely constrain burst source models. Recent reports (Quashnock and Lamb 1993; Wang and Lingenfelter 1993) of evidence for repetition in the first BATSE burst catalog have generated renewed interest in this issue. Here, we analyze the angular distribution of 585 bursts of the second BATSE catalog (Meegan et al. 1994). We search for evidence of burst recurrence using the nearest and farthest neighbor statistic and...

  10. GAMMA-RAY BURSTS, NEW COSMOLOGICAL BEACONS

    Directory of Open Access Journals (Sweden)

    V. Avila-Reese

    2009-01-01

    Full Text Available Long Gamma-Ray Bursts (GRBs are the brightest electromagnetic explosions in the Universe, associated to the death of massive stars. As such, GRBs are potential tracers of the evolution of the cosmic massive star formation, metallicity, and Initial Mass Function. GRBs also proved to be appealing cosmological distance indicators. This opens a unique opportunity to constrain the cosmic expansion history up to redshifts 5-6. A brief review on both subjects is presented here.

  11. Effects of 3 MeV proton irradiation on the mechanical properties of polyimide films

    Science.gov (United States)

    Hill, David J. T.; Hopewell, Jefferson L.

    1996-11-01

    The effects of 3 MeV proton irradiation on the elongation to break, fracture energy and Young's Modulus have been investigated for films of Kapton and Ultem over the dose range 0-75 MGy at ambient temperature. The results have been compared with those reported by other workers for irradiation by 60Co gamma rays and 2 MeV electron beams under similar conditions, and little difference was found between the damage to the mechanical properties of the films induced by these three beam types.

  12. On-line {sup 60}Co monitor for reactor recirculation system piping in primary containment vessel during reactor operation

    Energy Technology Data Exchange (ETDEWEB)

    Ueno, Katsunori, E-mail: katsunori.ueno.pa@hitachi.com [Hitachi Research Laboratory, Hitachi, Ltd., Hitachi 319-1224, Ibaraki (Japan); Tadokoro, Takahiro [Hitachi Research Laboratory, Hitachi, Ltd., Hitachi 319-1224, Ibaraki (Japan); Tsuyuki, Mizuho; Matsubara, Hirofumi; Ota, Nobuyuki; Nagase, Makoto [Hitachi-GE Nuclear Energy, Ltd., Hitachi 317-0073, Ibaraki (Japan)

    2014-10-15

    Highlights: • We developed an on-line {sup 60}Co monitor for reactor recirculation system piping during reactor operation. • Energy resolution at 1.4 × 10{sup 6} cps is 33 keV at 1332 keV using a pulse integral method. • A coincidence method is applied to reduce an effect of background gamma rays. • The coincidence counting of {sup 60}Co cascade gamma rays could be detected for a background dose rate of 4.8 mSv/h. - Abstract: Water chemistry control during reactor operation and installation of temporary radiation shielding prior to scheduled outages are carried out in order to reduce workers’ dose exposure caused by {sup 60}Co which is the main radiation source during scheduled outages of boiling water reactor (BWR) power plants. It is necessary to monitor the deposited {sup 60}Co on inner surfaces of reactor recirculation system (RRS) piping to evaluate effects of water chemistry control. We have developed an on-line {sup 60}Co monitor (OLCM) for this purpose. The OLCM applies a pulse integral method as a new method to measure gamma-ray counts of more than 1.0 × 10{sup 6} counts per second (cps) and a coincidence counting method to reduce an effect of background gamma rays caused by {sup 16}N in the measurement of {sup 60}Co cascade gamma rays. Energy resolution at 1.4 × 10{sup 6} cps is 33 keV using the pulse integral method and single LaBr{sub 3}:Ce scintillation detector. The energy resolutions of this detector using the fast response photo multiplier tube (PMT) are 50 keV at 1.5 × 10{sup 6} cps and 59 keV at 2.1 × 10{sup 6} cps. Furthermore, we measured the energy spectra using the pulse integral method, the coincidence counting method and two LaBr{sub 3}:Ce scintillation detectors and examined the transition of coincidence counting for {sup 60}Co detection under high dose rate during reactor operation at the Kyoto University Research Reactor (KUR). The coincidence counting of {sup 60}Co cascade gamma rays could be detected, and the result was

  13. Effects of low dose gamma-ray radiation on the seed germination and physiological activity of vegetable crops

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. S.; Baek, M. H.; Lee, Y. G. [KAERI, Taejon (Korea, Republic of); Jung, K. H. [Kyunghee Univ., Yongin (Korea, Republic of)

    2000-10-01

    To determine the effect of low dose gamma-ray radiation on the germination rate and physiology of germinative seeds of Chinese cabbage(Brassica campestris L. cv. Hanyoreum) and radish(Raphanus sativus L. cv. Chungsukoungzoung). The germination rate of irradiation group was higher than that of the control. Especially it was highest at the early stage of induction. The germination rate of Chinese cabbage increased at 4 Gy-, 10 Gy- and 50 Gy irradiation group and that of radish increased at 2 Gy-, 6 Gy- and 10 Gy irradiation group. The seedling height of Chinese cabbage and radish increased positively in low dose irradiation group. The seedling height of Chinese cabbage was noticeably higher at 4 Gy and 10 Gy irradiation group and that of radish at 6 Gy irradiation group. The protein contents of seeds irradiated with low dose gamma-ray radiation was increased compared to that of the control especially at the early stage of induction. The enzyme activity of seeds irradiated with low dose of gamma-ray radiation was increased at 4 Gy and 10 Gy irradiation group. These results suggest that the germination and physiological activity of old seeds could be stimulated promisingly by the low dose gamma-ray radiation.

  14. Gamma ray tracking with the AGATA demonstrator

    Energy Technology Data Exchange (ETDEWEB)

    Birkenbach, Benedikt; Hess, Herbert; Lewandowski, Lars; Reiter, Peter; Steinbach, Tim; Schneiders, David; Vogt, Andreas [IKP, Universitaet zu Koeln (Germany); Collaboration: AGATA-Collaboration

    2014-07-01

    The performance of the AGATA demonstrator will be discussed based on data taken from a multi-nucleon transfer experiment at the AGATA PRISMA setup at LNL (INFN, Italy). A primary {sup 136}Xe beam of 1 GeV hitting a {sup 238}U target was used to produce a multitude of nuclei in the vicinity of {sup 136}Xe and corresponding reaction partners in the actinide region. The obtained results for in-beam gamma-ray spectroscopy allow for a critical assessment of the novel gamma ray tracking technique and comparison with standard procedure. High resolution spectroscopy of both reaction products after multi-nucleon transfer reaction in the presence of a high background from excited fission fragments is based on pulse-shape analysis (PSA) and gamma-ray tracking (GRT). The quality of the position information is crucial for the final energy resolution after Doppler correction. The impact of the calculated PSA libraries and the initial detector characterization for the PSA and GRT are summarized. Details of the achieved position and energy resolution, peak-to-background optimization are presented and illustrated with results from the neutron-transfer products in Xe and U-isotopes.

  15. Gamma Ray Bursts Cook Book I: Formulation

    CERN Document Server

    Ziaeepour, Houri

    2008-01-01

    Since the suggestion of relativistic shocks as the origin of gamma-ray bursts (GRBs) in early 90's, the mathematical formulation of this process has stayed at phenomenological level. One of the reasons for the slow development of theoretical works in this domain has been the simple power-law behaviour of the afterglows hours or days after the prompt gamma-ray emission. Nowadays with the launch of the Swift satellite, gamma-ray bursts can be observed in multi-wavelength from a few tens of seconds after trigger onward. These observations have leaded to the discovery of features unexplainable by the simple formulation of the shocks and emission processes used up to now. But "devil is in details" and some of these features may be explained with a more detailed formulation of phenomena and without adhoc addition of new processes. Such a formulation is the goal of this work. We present a consistent formulation of the collision between two spherical relativistic shells. The model can be applied to both internal and ...

  16. Bremsstrahlung gamma rays from light Dark Matter

    CERN Document Server

    Cirelli, Marco; Zaharijas, Gabrijela

    2013-01-01

    We discuss the often-neglected role of bremsstrahlung processes on the interstellar gas in computing indirect signatures of Dark Matter (DM) annihilation in the Galaxy, particularly for light DM candidates in the phenomenologically interesting O(10) GeV mass range. Especially from directions close to the Galactic Plane, the expected gamma-ray spectrum is altered via two effects: directly, by the photons emitted in the bremsstrahlung process on the interstellar gas by energetic electrons which are among the DM annihilation byproducts; indirectly, by the modification of the same electron spectrum, due to the additional energy loss process in the diffusion-loss equation (e.g. the resulting inverse Compton emission is altered). We quantify the importance of the bremsstrahlung emission in the GeV energy range, showing that it is the dominant component of the gamma-ray spectrum for some cases. We also find that, in regions in which bremsstrahlung dominates energy losses, the related gamma-ray emission is only moder...

  17. Delayed Nickel Decay in Gamma Ray Bursts

    CERN Document Server

    McLaughlin, G C

    2002-01-01

    Recently observed emission lines in the X-ray afterglow of gamma ray bursts suggest that iron group elements are either produced in the gamma ray burst, or are present nearby. If this material is the product of a thermonuclear burn, then such material would be expected to be rich in Nickel-56. If the nickel remains partially ionized, this prevents the electron capture reaction normally associated with the decay of Nickel-56, dramatically increasing the decay timescale. Here we examine the consequences of rapid ejection of a fraction of a solar mass of iron group material from the center of a collapsar/hypernova. The exact rate of decay then depends on the details of the ionization and therefore the ejection process. Future observations of iron, nickel and cobalt lines can be used to diagnose the origin of these elements and to better understand the astrophysical site of gamma ray bursts. In this model, the X-ray lines of these iron-group elements could be detected in suspected hypernovae that did not produce ...

  18. RADIO FLARES FROM GAMMA-RAY BURSTS

    Energy Technology Data Exchange (ETDEWEB)

    Kopač, D.; Mundell, C. G.; Kobayashi, S.; Virgili, F. J. [Astrophysics Research Institute, Liverpool John Moores University, Liverpool, L3 5RF (United Kingdom); Harrison, R. [Department of Astrophysics, School of Physics and Astronomy, Tel Aviv University, 69978 Tel Aviv (Israel); Japelj, J.; Gomboc, A. [Faculty of Mathematics and Physics, University of Ljubljana, Jadranska 19, 1000 Ljubljana (Slovenia); Guidorzi, C. [Department of Physics and Earth Sciences, University of Ferrara, Via Saragat, 1, I-44122 Ferrara (Italy); Melandri, A., E-mail: D.Kopac@ljmu.ac.uk [INAF/Brera Astronomical Observatory, via Bianchi 46, I-23807, Merate (Italy)

    2015-06-20

    We present predictions of centimeter and millimeter radio emission from reverse shocks (RSs) in the early afterglows of gamma-ray bursts (GRBs) with the goal of determining their detectability with current and future radio facilities. Using a range of GRB properties, such as peak optical brightness and time, isotropic equivalent gamma-ray energy, and redshift, we simulate radio light curves in a framework generalized for any circumburst medium structure and including a parameterization of the shell thickness regime that is more realistic than the simple assumption of thick- or thin-shell approximations. Building on earlier work by Mundell et al. and Melandri et al. in which the typical frequency of the RS was suggested to lie at radio rather than optical wavelengths at early times, we show that the brightest and most distinct RS radio signatures are detectable up to 0.1–1 day after the burst, emphasizing the need for rapid radio follow-up. Detection is easier for bursts with later optical peaks, high isotropic energies, lower circumburst medium densities, and at observing frequencies that are less prone to synchrotron self-absorption effects—typically above a few GHz. Given recent detections of polarized prompt gamma-ray and optical RS emission, we suggest that detection of polarized radio/millimeter emission will unambiguously confirm the presence of low-frequency RSs at early time.

  19. Gamma-Ray Pulsars Models and Predictions

    CERN Document Server

    Harding, A K

    2001-01-01

    Pulsed emission from gamma-ray pulsars originates inside the magnetosphere, from radiation by charged particles accelerated near the magnetic poles or in the outer gaps. In polar cap models, the high energy spectrum is cut off by magnetic pair production above an energy that is dependent on the local magnetic field strength. While most young pulsars with surface fields in the range B = 10^{12} - 10^{13} G are expected to have high energy cutoffs around several GeV, the gamma-ray spectra of old pulsars having lower surface fields may extend to 50 GeV. Although the gamma-ray emission of older pulsars is weaker, detecting pulsed emission at high energies from nearby sources would be an important confirmation of polar cap models. Outer gap models predict more gradual high-energy turnovers at around 10 GeV, but also predict an inverse Compton component extending to TeV energies. Detection of pulsed TeV emission, which would not survive attenuation at the polar caps, is thus an important test of outer gap models. N...

  20. Afterglow Radiation from Gamma Ray Bursts

    Energy Technology Data Exchange (ETDEWEB)

    Desmond, Hugh; /Leuven U. /SLAC

    2006-08-28

    Gamma-ray bursts (GRB) are huge fluxes of gamma rays that appear randomly in the sky about once a day. It is now commonly accepted that GRBs are caused by a stellar object shooting off a powerful plasma jet along its rotation axis. After the initial outburst of gamma rays, a lower intensity radiation remains, called the afterglow. Using the data from a hydrodynamical numerical simulation that models the dynamics of the jet, we calculated the expected light curve of the afterglow radiation that would be observed on earth. We calculated the light curve and spectrum and compared them to the light curves and spectra predicted by two analytical models of the expansion of the jet (which are based on the Blandford and McKee solution of a relativistic isotropic expansion; see Sari's model [1] and Granot's model [2]). We found that the light curve did not decay as fast as predicted by Sari; the predictions by Granot were largely corroborated. Some results, however, did not match Granot's predictions, and more research is needed to explain these discrepancies.

  1. Hadronic Gamma Rays from Supernova Remnants

    CERN Document Server

    Moskalenko, I V; Malkov, M A; Diamond, P H

    2007-01-01

    A gas cloud near a supernova remnant (SNR) provides a target for pp-collisions leading to subsequent gamma-ray emission through neutral pion decay. The assumption of a power-law ambient spectrum of accelerated particles with index near -2 is usually built into models predicting the spectra of very-high energy (VHE) gamma-ray emission from SNRs. However, if the gas cloud is located at some distance from the SNR shock, this assumption is not necessarily correct. In this case, the particles which interact with the cloud are those leaking from the shock and their spectrum is approximately monoenergetic with the injection energy gradually decreasing as the SNR ages. The gamma-ray spectrum resulting from particle interactions with the gas cloud will be flatter than expected, with the cutoff defined by the pion momentum distribution in the laboratory frame. We evaluate the flux of particles escaping from a SNR shock and apply the results to the VHE diffuse emission detected by the HESS at the Galactic centre.

  2. Gamma-Ray Bursts and Marine Primary Producers

    Science.gov (United States)

    Thomas, Brian; Neale, P. J.

    2011-01-01

    Gamma-ray bursts (GRB) have been recognized as a potential threat to life on Earth, primarily through long-term depletion of stratospheric ozone, leading to greatly increased solar ultraviolet (UV) irradiance at the surface. It has been suggested that a GRB may have initiated the late Ordovician mass extinction - one of the "big five" known extinctions. Past efforts by our group to estimate the biological impact of a GRB have used a simplified Beer-Lambert calculation with an ozone column density to estimate surface UV irradiance. Biological damage was then computed by combining the irradiance with a biological weighting function (BWF) for DNA damage. We are currently engaged in a project to greatly increase the accuracy of these estimates, with a focus on the impact on primary producers in the Earth's oceans. These organisms make up the base of the marine food web and produce half the world's oxygen. Our approach features full radiative transfer modeling to determine surface UV irradiance, combined with newly measured biological weighting functions for some of the most abundant marine primary producers. Here, we report on preliminary results of this study, including computed spectral irradiance at the surface and in ocean water under conditions following a GRB, along with the impact on primary productivity as computed using preliminary BWF results. This work is supported by NASA's Astrobiology: Exobiology and Evolutionary Biology program, grant #NNX09AM85G.

  3. Gamma-ray Output Spectra from 239Pu Fission

    Directory of Open Access Journals (Sweden)

    Ullmann John

    2015-01-01

    Full Text Available Gamma-ray multiplicities, individual gamma-ray energy spectra, and total gamma energy spectra following neutron-induced fission of 239Pu were measured using the DANCE detector at Los Alamos. Corrections for detector response were made using a forward-modeling technique based on propagating sets of gamma rays generated from a paramaterized model through a GEANT model of the DANCE array and adjusting the parameters for best fit to the measured spectra. The results for the gamma-ray spectrum and multiplicity are in general agreement with previous results, but the measured total gamma-ray energy is about 10% higher. A dependence of the gamma-ray spectrum on the gamma-ray multplicity was also observed. Global model calculations of the multiplicity and gamma energy distributions are in good agreement with the data, but predict a slightly softer total-energy distribution.

  4. News from Cosmic Gamma-ray Line Observations

    CERN Document Server

    Diehl, Roland

    2016-01-01

    The measurement of gamma rays at MeV energies from cosmic radioactivities is one of the key tools for nuclear astrophysics, in its study of nuclear reactions and how they shape objects such as massive stars and supernova explosions. Additionally, the unique gamma-ray signature from the annihilation of positrons falls into this same astronomical window, and positrons are often produced from radioactive beta decays. Nuclear gamma-ray telescopes face instrumental challenges from penetrating gamma rays and cosmic-ray induced backgrounds. But the astrophysical benefits of such efforts are underlined by the discoveries of nuclear gamma~rays from the brightest of the expected sources. In recent years, both thermonuclear and core-collapse supernova radioactivity gamma~rays have been measured in spectral detail, and complement conventional supernova observations with measurements of origins in deep supernova interiors, from the decay of $^{56}$Ni, $^{56}$Co, and $^{44}$Ti. The diffuse afterglow in gamma rays of radioa...

  5. Measurement of fast neutrons and secondary gamma rays in graphite

    Energy Technology Data Exchange (ETDEWEB)

    Makarious, A.S.; El-Asyd Abdo, A.; Kansouh, W.A. [Atomic Energy Authority, Cairo (Egypt). Nuclear Research Centre; Bashter, I.I. [Zagazig Univ. (Egypt). Faculty of Science

    1996-05-01

    The spatial fluxes and energy distributions of fast neutrons, total gamma rays and secondary gamma rays transmitted through different thicknesses of graphite have been measured. The graphite samples were arranged in front of one of the horizontal channels of the ET-RR-1 reactor. Gamma ray measurements were carried out for bare, cadmium filtered and boron carbide filtered reactor beams. A fast neutron and gamma ray spectrometer with a stilbene crystal was used to measure the spectrum of fast neutrons and gamma rays. Pulse shape discrimination using the zero cross over technique was used to distinguish the proton pulses from the electron pulses. The total fast neutrons macroscopic cross section and the linear attenuation coefficient for gamma rays were derived both for the whole energy range and at different energies. The obtained values were used to calculate the relaxation lengths for fast neutrons and gamma rays. (Author).

  6. Re-estimation of absolute gamma ray intensities of 56Mn using k0- standardization

    Institute of Scientific and Technical Information of China (English)

    M. AHMAD; W. AHMAD; M. U. RAJPUT; A. QAYYUM

    2005-01-01

    The thermal neutron capture gamma ray facility at Pakistan Research Reactor (PARR-1) is being used for the re-estimation of various properties like capture cross-sections, resonance integral, absolute gamma intensities, etc.of different isotopes. The data for gamma ray transitions from the capture of thermal neutrons by 55Mn are not in good agreement specifically below 2 MeV. So there is a need to re-estimate its intensities with better accuracy. Analytical grade MnCl2 powder and high purity Mn metal pieces were used in this study. Standard 152Eu and 60Co radioactive sources as well as thermal neutron capture γ-rays in chlorine were chosen for efficiency calibration. The k0standardization technique was applied for these measurements to eliminate systematic errors in efficiencies. Chlorine also acted as a comparator in k0- factor calculations. The results have been tabulated for the main gamma rays from 56Mn in the low as well as in the medium energy regions. The absolute intensities are in good agreement with most of the reported values.

  7. Radioisotope identification method for poorly resolved gamma-ray spectrum of nuclear security concern

    Energy Technology Data Exchange (ETDEWEB)

    Ninh, Giang Nguyen; Phongphaeth, Pengvanich, E-mail: phongphaeth.p@chula.ac.th; Nares, Chankow [Nuclear Engineering Department, Faculty of Engineering, Chulalongkorn University, 254 Phayathai Road, Pathumwan, Bangkok 10330 (Thailand); Hao, Quang Nguyen [Vietnam Atomic Energy Institute, Ministry of Science and Technology, Hanoi (Viet Nam)

    2016-01-22

    Gamma-ray signal can be used as a fingerprint for radioisotope identification. In the context of radioactive and nuclear materials security at the border control point, the detection task can present a significant challenge due to various constraints such as the limited measurement time, the shielding conditions, and the noise interference. This study proposes a novel method to identify the signal of one or several radioisotopes from a poorly resolved gamma-ray spectrum. In this method, the noise component in the raw spectrum is reduced by the wavelet decomposition approach, and the removal of the continuum background is performed using the baseline determination algorithm. Finally, the identification of radioisotope is completed using the matrix linear regression method. The proposed method has been verified by experiments using the poorly resolved gamma-ray signals from various scenarios including single source, mixing of natural uranium with five of the most common industrial radioactive sources (57Co, 60Co, 133Ba, 137Cs, and 241Am). The preliminary results show that the proposed algorithm is comparable with the commercial method.

  8. Radioisotope identification method for poorly resolved gamma-ray spectrum of nuclear security concern

    Science.gov (United States)

    Ninh, Giang Nguyen; Phongphaeth, Pengvanich; Nares, Chankow; Hao, Quang Nguyen

    2016-01-01

    Gamma-ray signal can be used as a fingerprint for radioisotope identification. In the context of radioactive and nuclear materials security at the border control point, the detection task can present a significant challenge due to various constraints such as the limited measurement time, the shielding conditions, and the noise interference. This study proposes a novel method to identify the signal of one or several radioisotopes from a poorly resolved gamma-ray spectrum. In this method, the noise component in the raw spectrum is reduced by the wavelet decomposition approach, and the removal of the continuum background is performed using the baseline determination algorithm. Finally, the identification of radioisotope is completed using the matrix linear regression method. The proposed method has been verified by experiments using the poorly resolved gamma-ray signals from various scenarios including single source, mixing of natural uranium with five of the most common industrial radioactive sources (57Co, 60Co, 133Ba, 137Cs, and 241Am). The preliminary results show that the proposed algorithm is comparable with the commercial method.

  9. Heterogeneity of chromosome damage in [beta]-thalassaemia traits. An evaluation of spontaneous and [gamma]-ray-induced micronuclei and chromosome aberrations in lymphocytes in vitro after G[sub 0] and G[sub 2] phase irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Krishnaja, A.P.; Sharma, N.K. (Bhabha Atomic Research Centre, Bombay (India). Molecular Biology and Agriculture Div.)

    1994-07-01

    This study is an attempt to evaluate the chromosomal radiosensitivity of [beta]-thalassaemia traits compared with healthy individuals from the general population, necessitated by the fact that [beta]-thalassaemia trait is present in 1-17% of different population groups in India and the chances of encountering them in radiation and chemical related industries do exist. Spontaneous chromosome aberration frequencies in peripheral blood lymphocytes from [beta]-thalassaemia traits were found to be in the normal range, whereas significantly higher frequencies of micronuclei (MN) were observed in thalassaemia traits. Based on MN frequency at 2 Gy, [beta]-thalassaemia traits fall into two distinct categories. A hypersensitive group with significant increase in radiation-induced MN over the control group, and a second group with MN frequency slightly above normal individuals. Even when compared with the fitted data at 2 Gy obtained from the pooled results of extensive dose-response investigations from 0.5-5 Gy [gamma]-rays with normal donors for MN, dicentrics and total aberrations, the difference between the means of MN frequencies in [beta]-thalassaemia traits and normals is significant. (author).

  10. Estudo do efeito da irradiação gamma (60CO na qualidade da cachaça e no tonel de envelhecimento Study of the effect of gamma irradiation (60co on the quality of sugar cane spirit and on the cask of maturation

    Directory of Open Access Journals (Sweden)

    Mariana Branco de Miranda

    2006-12-01

    Full Text Available O processo de envelhecimento ou maturação das bebidas proporciona uma melhora nas características sensoriais da cachaça, tornando-a de qualidade superior e de maior valor econômico. O método tradicional de maturação de bebidas é sua interação com madeiras, sendo que a irradiação pode acelerar este processo de envelhecimento. A cachaça e os tonéis de carvalho de 20 L de capacidade foram submetidos à irradiação gama (150 Gy. Análises físico-químicas e cromatográficas foram realizadas periodicamente ao longo de 390 dias do período de envelhecimento da bebida. A irradiação da cachaça e do tonel não alterou a maioria dos componentes voláteis do coeficiente de congêneres como acidez volátil, ésteres, álcoois superiores e furfural durante os 390 dias. Há evidências, entretanto, de que os parâmetros de alguns componentes como aldeídos, taninos, cor e teor de cobre são de alguma forma influenciados, resultando em aceleração parcial do processo de maturação ou envelhecimento. Ao final do período de envelhecimento, foi feita uma análise sensorial com 30 provadores não treinados. A aceleração do processo de envelhecimento foi confirmada pela avaliação sensorial, e a cachaça e/ou tonel irradiados receberam maior indicação de aprovação em todos os parâmetros analisados (aroma, sabor e aparência.The ageing or maturing process of drink improves the sensorial characteristics of the product making it a qualified drink with higher economical value. The traditional maturing method of drinks involves their interaction with wood and irradiation can accelerate this ageing process. Sugar cane spirit and oak barrels with a 20 L capacity were treated using gamma irradiation (150 Gy. Physical-chemical and chromatographic analyses were constantly performed for 390 days during the drink ageing period. The sugar cane spirit and barrel irradiation did not change most volatile components of the same type coefficient such

  11. Selection of mutants of capsicum annuum induced by gamma ray

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Y. I.; Lee, Y. B. [Korea Atomic Energy Research Institute, Taejeon (Korea, Republic of); Lee, E. K. [Chungnam National Univ., Taejeon (Korea, Republic of)

    1998-06-01

    For induction and selection of mutations of Capsicum annuum L., dry seeds of pure lines No.1 and No.2 were irradiated with gamma ray of 150Gy, 200Gy and 250Gy. Various mutants were selected such as showing early maturity, short plant height, long fruit and chlorophyll mutations. Mutation frequency of No.1 line was 3.4% in the dose of 150Gy, while the frequency of No.2 line was 2.7% in the dose of 250Gy. For selection of resistant mutant to amino acid analog, the optimum concentration of 5-methyltryptophan (5-MT) and S-(2-aminoethyl)-L-cysteine were 25 ppm and 30 ppm, respectively. Four resistant mutant lines to 5-MT were selected among 400 mutant lines.

  12. Effect of gamma-rays on Capsicum annuum L. Embriogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Ilieva, I. (Bylgarska Akademiya na Naukite, Sofia. Inst. po Genetika)

    1982-01-01

    The effect of gamma-rays (0.5-1.5 krad) on the growth and organogenesis of the C. annuum embryo was studied by observations in vivo of ripe seeds, after treatments in the stages of middle and late proembryo. It was found that doses of about 1.5 krad were sublethal for both stages observed: they cause an early cessation of the embryo's growth and inhibit seed germination. Disturbances in cotyledon formations were: no differentiation took place and cotyledon anomalies appeared (heterocotyls - up to 20.3%, monocotyls -up to 5.7%, polycotyls - up to 8.5%). The late proembryo stage (late globular) manifested higher and specific sensitivity towards the appearance of cotyledon anomalies: up to 47.1% of the embryos (after 0.5 krad irradiation) had disturbances in the formation of the cotyledons.

  13. High energy gamma-ray emission from Gamma-Ray Bursts -- before GLAST

    CERN Document Server

    Fan, Yi-Zhong

    2008-01-01

    Gamma-ray bursts (GRBs) are short and intense emission of soft gamma-rays, which have fascinated astronomers and astrophysicists since their unexpected discovery in 1960s. The X-ray/optical/radio afterglow observations confirm the cosmological origin of GRBs, support the fireball model, and imply a long-activity of the central engine. The high energy gamma-ray emission (>20 MeV) from GRBs is particularly important because they shed some lights on the radiation mechanisms and can help us to constrain the physical processes giving rise to the early afterglows. In this work, we review observational and theoretical studies of the high energy emission from GRBs. Special attention is given to the expected high energy emission signatures accompanying the canonical early-time X-ray afterglow that was observed by the Swift X-ray Telescope. We also discuss the detection prospect of the upcoming GLAST satellite and the current ground-based Cerenkov detectors.

  14. Development of the measurement technique for nuclear data with prompt gamma-ray spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Shoji; Furutaka, Kazuyoshi; Harada, Hideo [Japan Nuclear Cycle Development Inst., Tokai, Ibaraki (Japan). Tokai Works

    2002-09-01

    To obtain the thermal neutron capture cross sections of radioactive fission product nuclides as the basic data on transmutation study, a measurement technique with prompt gamma-ray spectroscopy was developed. When daughter nuclides after neutron irradiations are stable, measuring the neutron capture cross sections is impossible. Therefore, a new technique was developed to investigate these. With this, the level schemes from the information of the prompt {gamma}-rays emitted during neutron irradiation are constructed, and the cross section is deduced with the emission probabilities of prompt {gamma}-rays. The measurement system for this technique was developed, and was effective. The system enables obtaining information on the cascade {gamma}-rays necessary for constructing the level-scheme. By measuring {sup nat}Pd, the partial level-scheme was constructed, and two new levels at 1906 keV and 2400 keV were identified. By using this technique, the neutron capture cross sections of nuclides that can't be measured by an activation method can be measured. (author)

  15. Evaluation of immunity and protection induced in experimental models by soluble extract of Toxoplasma gondii tachyzoites irradiated by {sup 60}Co; Avaliacao da imunidade e protecao induzida em modelos experimentais por extrato soluvel de taquizoitos de Toxoplasma gondii irradiado por {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Andrea da

    2013-07-01

    Toxoplasmosis affects 1/3 of the human population and only a vaccine for veterinary use. Gamma radiation alters the proteins making them more immunogenic by oxidation and better antigen presentation in the absence of adjuvants. Radiate soluble extract of RH strain tachyzoites of T. gondii (AgTg), and evaluate its use as a vaccine in BALB/c. Doses below 500Gy not affected and destroyed 2000Gy doses above extract, whereas animals immunized with irradiated extract at 1000, 1500 and 2000Gy had more of specific IgG avidity , compared to native AgTg (p<0,05) . AgTg 1500GY the immunized animals had increased proliferation of splenocytes, phenotyped as CD3+CD4+, CD3+CD8+ and B-lymphocytes immunized animals compared to the native AgTg . Animals immunized by AgTg 1500GY after challenge with strain ME- 49 cystogenic showed lower number of brain cysts and greater survival after challenge with virulent RH. Ionizing radiation in extracts of T. gondii increases the immune response and immune memory in the absence of adjuvants. (author)

  16. GAMMA RAYS FROM STAR FORMATION IN CLUSTERS OF GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Storm, Emma M.; Jeltema, Tesla E.; Profumo, Stefano [Department of Physics, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States)

    2012-08-20

    Star formation in galaxies is observed to be associated with gamma-ray emission, presumably from non-thermal processes connected to the acceleration of cosmic-ray nuclei and electrons. The detection of gamma rays from starburst galaxies by the Fermi Large Area Telescope (LAT) has allowed the determination of a functional relationship between star formation rate and gamma-ray luminosity. Since star formation is known to scale with total infrared (8-1000 {mu}m) and radio (1.4 GHz) luminosity, the observed infrared and radio emission from a star-forming galaxy can be used to quantitatively infer the galaxy's gamma-ray luminosity. Similarly, star-forming galaxies within galaxy clusters allow us to derive lower limits on the gamma-ray emission from clusters, which have not yet been conclusively detected in gamma rays. In this study, we apply the functional relationships between gamma-ray luminosity and radio and IR luminosities of galaxies derived by the Fermi Collaboration to a sample of the best candidate galaxy clusters for detection in gamma rays in order to place lower limits on the gamma-ray emission associated with star formation in galaxy clusters. We find that several clusters have predicted gamma-ray emission from star formation that are within an order of magnitude of the upper limits derived in Ackermann et al. based on non-detection by Fermi-LAT. Given the current gamma-ray limits, star formation likely plays a significant role in the gamma-ray emission in some clusters, especially those with cool cores. We predict that both Fermi-LAT over the course of its lifetime and the future Cerenkov Telescope Array will be able to detect gamma-ray emission from star-forming galaxies in clusters.

  17. Photocatalysis degradation of ethylene with γ-ray irradiated modified silver-doped TiO2%60Co-γ辐照改性银掺杂纳米TiO2及光催化降解乙烯

    Institute of Scientific and Technical Information of China (English)

    沈生文; 叶盛英; 宋贤良; 李明波; 方一超

    2012-01-01

    为了解60Co-γ射线辐照且以活性炭纤维(ACF)为载体所负载TiO2的半导体材料(TiO2/ACF)对光催化降解冷藏环境中乙烯的影响,该文拟采用60Co-γ辐照制备纳米Ag沉积的TiO2/ACF (Ag-TiO2/ACF)光催化材料,在模拟园艺产品的冷藏环境中,进行了3种不同膜的光催化降解乙烯效果的研究,并利用场发射扫描电镜(FESEM)、透射电子显微镜(TEM)、X射线衍射仪(XRD)对所制备的光催化材料进行相关的表征分析.结果表明:在加入分散剂聚乙烯吡咯烷酮后,60C0-γ辐照能使Ag颗粒较好地负载在TiO2上,TiO2均匀分散在ACF膜上而不发生团聚,且TiO2颗粒晶相改变、尺寸变小,有助于提高Ag-TiO2/ACF的催化效率.Ag-TiO2/ACF光催化降解乙烯的效果用一级动力学速率方程描述;经辐照制备的Ag-TiO2/ACF薄膜比未辐照的TiO2/ACF和辐照的TiO2/ACF薄膜光催化降解乙烯的反应速率常数分别提高了44%和37%.研究结果为TiO2光催化技术的进一步的应用提供了参考.%In order to investigate the effect of TiO2 irradiated by 60Co-y ray and loaded by activated carbon fibers on photocatalytic degradation of ethylene in the environment of cold storage, the TiCVACF photocatalytic materials deposited with nano-Ag (Ag-TiO2/ACF) irradiated by 60Co-y ray were prepared, and effects of three different films on the photocatalytic degradation rate of ethylene were investigated in the simulated cold storage environment for horticultural products. Environmental Scanning Electron Microscope (ESEM), Field Scanning Electron Microscope (FESEM) and X-ray diffractometer (XRD) were used to analyze the characterizations of the prepared Ag-TiO2/ACF. Results showed that: 60Co-y ray could make Ag load on the surface of TiO2 well and TiO2 could be dispersed on the ACF uniformly after adding the dispersant of polyethylene pyrrolidone, which could effectively prevent the aggregation of the nano-particles. The average particle size of TiO2

  18. Two classes of gamma-ray bursts

    CERN Document Server

    Katz, J I

    1995-01-01

    Data from the 3B Catalogue suggest that short and long GRB are the results of different classes of events, rather than different parameter values within a single class: Short bursts have harder spectra in the BATSE bands, but chiefly long bursts are detected at photon energies over 1 MeV, implying that their hard photons are radiated by a process not found in short bursts. The values of \\langle V/V_{max} \\rangle for short and long bursts differ by 4.3 \\sigma, implying different spatial distributions. Only the soft gamma-ray radiation mechanisms are the same in both classes.

  19. Material recognition using fission gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Viesti, G. [Dipartimento di Fisica dell' Universita di Padova, Via Marzolo 8, I-35131 Padova (Italy); INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy)], E-mail: giuseppe.viesti@pd.infn.it; Sajo-Bohus, L. [Universidad Simon-Bolivar, Laboratorio Fisica Nuclear, Apartado 8900, 1080 A. Caracas (Venezuela, Bolivarian Republic of); Fabris, D. [INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy); Lunardon, M.; Moretto, S. [Dipartimento di Fisica dell' Universita di Padova, Via Marzolo 8, I-35131 Padova (Italy); INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy); Nebbia, G.; Pesente, S. [INFN Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy)

    2009-07-21

    Material recognition is studied by measuring the transmission spectrum of {sup 252}Cf fission gamma rays in the energy range E{sub {gamma}}=0.1-5.5 MeV for 0.1-MeV-wide energy bins through a number of elementary samples. Each transmitted spectrum is compared with a library of reference spectra for different elements providing the possibility of material identification. In case of elemental samples with known thickness, this procedure allows the identification of the sample Z with uncertainty typically lower than 3 Z-units over a wide range of elements. Applications to composite materials are also reported.

  20. Gamma ray constraints on decaying dark matter

    DEFF Research Database (Denmark)

    Cirelli, M.; Moulin, E.; Panci, P.

    2012-01-01

    We derive new bounds on decaying dark matter from the gamma ray measurements of (i) the isotropic residual (extragalactic) background by Fermi and (ii) the Fornax galaxy cluster by H.E.S.S. We find that those from (i) are among the most stringent constraints currently available, for a large range...... of dark matter masses and a variety of decay modes, excluding half-lives up to similar to 10(26) to few 10(27) seconds. In particular, they rule out the interpretation in terms of decaying dark matter of the e(+/-) spectral features in PAMELA, Fermi and H.E.S.S., unless very conservative choices...

  1. Multiwavelength Studies of gamma-ray Binaries

    Science.gov (United States)

    Aragona, Christina

    2011-01-01

    High mass X-ray binaries (HMXBs) consist of an O or B star orbited by either a neutron star or a black hole. Of the 114 known Galactic HMXBs, a handful of these objects, dubbed gamma-ray binaries, have been observed to produce MeV-TeV emission. The very high energy emission can be produced either by accretion from the stellar wind onto a black hole or a collision between the stellar wind and a relativistic pulsar wind. Both these scenarios make gamma-ray binaries valuable nearby systems for studying the physics of shocks and jets. Currently, the nature of the compact object and the high energy production mechanism is unknown or unconfirmed in over half of these systems. My goal for this dissertation is to constrain the parameters describing two of these systems: LS 5039 and HD 259440. LS 5039 exhibits gamma-ray emission modulated with its orbital period. The system consists of an ON6.5V((f)) star and an unidentified compact companion. Using optical spectra from the CTIO 1.5m telescope, we found LS 5039 to have an orbital period of 3.90608 d and an eccentricity of 0.337. Spectra of the Halpha line observed with SOAR indicate a mass loss rate of ˜ 1.9x10 -8 M yr-1. Observations taken with ATCA at 13 cm, 6 cm, and 3 cm indicate radio fluxes between 10--40 mJy. The measurements show variability with time, indicating a source other than thermal emission from the stellar wind. HD 259440 is a B0pe star that was proposed as the optical counterpart to the gamma-ray source HESS J0632+057. Using optical spectra from the KPNO CF, KPNO 2.1m, and OHP telescopes, we find a best fit stellar effective temperature of 27500--30000 K, a log surface gravity of 3.75--4.0, a mass of 13.2--19.0 Msolar, and a radius of 6.0--9.6 Rsolar. By fitting the spectral energy distribution, we find a distance between 1.1--1.7 kpc. We do not detect any significant radial velocity shifts in our data, ruling out orbital periods shorter than one month. If HD 259440 is a binary, it is likely a long

  2. The Nature of Gamma Ray Burst Supernovae

    OpenAIRE

    Cano, Zach

    2012-01-01

    Gamma Ray Bursts (GRBs) and Supernovae (SNe) are among the brightest and most energetic physical processes in the universe. It is known that core-collapse SNe arise from the gravitational collapse and subsequent explosion of massive stars (the progen- itors of nearby core-collapse SNe have been imaged and unambiguously identified). It is also believed that the progenitors of long-duration GRBs (L-GRBs) are massive stars, mainly due to the occurrence and detection of very energetic core-collap...

  3. Properties of $\\gamma$-Ray Burst Classes

    CERN Document Server

    Hakkila, J; Roiger, R J; Mallozzi, R S; Pendleton, G N; Meegan, C A; Hakkila, Jon; Haglin, David J.; Roiger, Richard J.; Mallozzi, Robert S.; Pendleton, Geoffrey N.; Meegan, Charles A.

    2000-01-01

    The three gamma-ray burst (GRB) classes identified by statistical clustering analysis (Mukherjee et al. 1998) are examined using the pattern recognition algorithm C4.5 (Quinlan 1986). Although the statistical existence of Class 3 (intermediate duration, intermediate fluence, soft) is supported, the properties of this class do not need to arise from a distinct source population. Class 3 properties can easily be produced from Class 1 (long, high fluence, intermediate hardness) by a combination of measurement error, hardness/intensity correlation, and a newly-identified BATSE bias (the fluence duration bias). Class 2 (short, low fluence, hard) does not appear to be related to Class 1.

  4. Digital Logarithmic Airborne Gamma Ray Spectrometer

    OpenAIRE

    2014-01-01

    A new digital logarithmic airborne gamma ray spectrometer is designed in this study. The spectrometer adopts a high-speed and high-accuracy logarithmic amplifier (LOG114) to amplify the pulse signal logarithmically and to improve the utilization of the ADC dynamic range, because the low-energy pulse signal has a larger gain than the high-energy pulse signal. The spectrometer can clearly distinguish the photopeaks at 239, 352, 583, and 609keV in the low-energy spectral sections after the energ...

  5. Nucleosynthetic Yields from Gamma-Ray Bursts

    CERN Document Server

    Rockefeller, Gabriel; Young, Patrick; Bennett, Michael; Diehl, Steven; Herwig, Falk; Hirschi, Raphael; Hungerford, Aimee; Pignatari, Marco; Magkotsios, Georgios; Timmes, Francis X

    2008-01-01

    The "collapsar" engine for gamma-ray bursts invokes as its energy source the failure of a normal supernova and the formation of a black hole. Here we present the results of the first three-dimensional simulation of the collapse of a massive star down to a black hole, including the subsequent accretion and explosion. The explosion differs significantly from the axisymmetric scenario obtained in two-dimensional simulations; this has important consequences for the nucleosynthetic yields. We compare the nucleosynthetic yields to those of hypernovae. Calculating yields from three-dimensional explosions requires new strategies in post-process nucleosynthesis; we discuss NuGrid's plan for three-dimensional yields.

  6. Late effects of total-head gamma irradiation in mice. 2. Pathomorphological analysis of organic changes with regard to the role of the hypophysis - adrenal gland axis and of the thymolymphatic system

    Energy Technology Data Exchange (ETDEWEB)

    Tkadlecek, L.; Viklicka, S.; Karpfel, Z.; Pospisil, M.; Netikova, J. (Ceskoslovenska Akademie Ved, Brno. Biofysikalni Ustav)

    1985-01-01

    Relations between late manifestations of wasting of C57BL/10 mice whose heads were irradiated with a dose of 16 Gy of /sup 60/Co gamma rays, and some pathomorphological findings in the organs of animals in the late period after irradiation were studied. A close correlation was found between the fall in body weight of animals during the period of the 6th month after irradiation and involution of the thymolymphatic system. Adenohypophysis and adrenal cortex of wasting animals revealed clear signs of structural defects, indicating failure of their hormonal functions. Morphological examination of brain, cerebellum, duodenum and liver did not exhibit signs of damage.

  7. Polarized gamma-rays with laser-Compton backscattering

    Energy Technology Data Exchange (ETDEWEB)

    Ohgaki, H.; Noguchi, T.; Sugiyama, S. [Electrotechnical Lab., Ibaraki (Japan)] [and others

    1995-12-31

    Polarized gamma-rays were generated through laser-Compton backscattering (LCS) of a conventional Nd:YAG laser with electrons circulating in the electron storage ring TERAS at Electrotechnical Laboratory. We measured the energy, the energy spread, and the yield of the gamma-rays to characterize our gamma-ray source. The gamma-ray energy can be varied by changing the energy of the electrons circulating the storage ring. In our case, the energy of electrons in the storage ring were varied its energy from 200 to 750 MeV. Consequently, we observed gamma-ray energies of 1 to 10 MeV with 1064 run laser photons. Furthermore, the gamma-ray energy was extended to 20 MeV by using the 2nd harmonic of the Nd:YAG laser. This shows a good agreement with theoretical calculation. The gamma-ray energy spread was also measured to be 1% FWHM for -1 MeV gamma-rays and to be 4% FWHM for 10 MeV gamma-rays with a narrow collimator that defined the scattering cone. The gamma-ray yield was 47.2 photons/mA/W/s. This value is consistent with a rough estimation of 59.5 photons/mA/W/s derived from theory. Furthermore, we tried to use these gamma-rays for a nuclear fluorescence experiment. If we use a polarized laser beam, we can easily obtain polarized gamma-rays. Elastically scattered photons from {sup 208} Pb were clearly measured with the linearly polarized gamma-rays, and we could assign the parity of J=1 states in the nucleus. We should emphasize that the polarized gamma-ray from LCS is quit useful in this field, because we can use highly, almost completely, polarized gamma-rays. We also use the LCS gamma-rays to measure the photon absorption coefficients. In near future, we will try to generate a circular polarized gamma-ray. We also have a plan to use an FEL, because it can produce intense laser photons in the same geometric configuration as the LCS facility.

  8. Molecular and biochemical studies on the effect of gamma rays on lead toxicity in cowpea (Vigna sinensis) plants.

    Science.gov (United States)

    Mohamed, Heba Ibrahim

    2011-12-01

    The effect of lead acetate in the presence or absence of cowpea seeds irradiated with gamma rays on morphological criteria, protein electrophoresis, isozymes, and random amplification of polymorphic DNA-polymerase chain reaction (RAPD-PCR) of leaves was investigated. A highly significant decrease in shoot and root length was observed upon lead acetate exposure (300 and 600 μM). On the other hand, in seeds irradiated with gamma rays (2, 5, and 8 krad), these morphological parameters were increased after lead acetate treatments. Meanwhile, all treatments (lead acetate and gamma rays) caused variations in number, intensity, and/or density of SDS electrophoretic bands of proteins. In addition, electrophoretic studies of esterase, acid phosphatase, peroxidase, polyphenol oxidase, catalase, and superoxide dismutase isozyme activities were increased with increasing the concentrations of lead acetate and gamma ray doses. The variation in DNA profile in response to lead acetate and gamma irradiation treatments was detected by RAPD-PCR technique. The result of RAPD analysis using the five primers indicated the appearance and disappearance of DNA polymorphic bands at all treatments (gamma rays and lead stress). The relatively high concentrations of lead acetate (600 μM) induced more changes in genomic DNA pattern.

  9. Comparative study of neutron and gamma-ray pulse shape discrimination of anthracene, stilbene, and p-terphenyl

    Energy Technology Data Exchange (ETDEWEB)

    Yanagida, Takayuki, E-mail: yanagida@lsse.kyutech.ac.jp [Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, Fukuoka 808-0196 (Japan); Watanabe, Kenichi [Nagoya University, Furocho, Chikusa, Nagoya 464-8603 (Japan); Fujimoto, Yutaka [Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, Fukuoka 808-0196 (Japan)

    2015-06-01

    Solid state organic scintillators, such as anthracene, stilbene, and p-terphenyl were investigated on their basic scintillation properties and neutron–gamma discrimination capabilities. Scintillation wavelengths under X-ray irradiation of anthracene, stilbene, and p-terphenyl were 445–525, 400–500, and 350–450 nm, respectively. Scintillation light yields of anthracene, stilbene, and p-terphenyl under {sup 137}Cs gamma-ray irradiation were 20100, 16000, and 19400 ph/MeV, respectively. Neutron and gamma-ray events discrimination capabilities were examined and anthracene exhibited the best figure of merit among three organic scintillators.

  10. Highlights of GeV Gamma-Ray Astronomy

    Science.gov (United States)

    Thompson, David J.

    2010-01-01

    Because high-energy gamma rays are primarily produced by high-energy particle interactions, the gamma-ray survey of the sky by the Fermi Gamma-ray Space Telescope offers a view of sites of cosmic ray production and interactions. Gamma-ray bursts, pulsars, pulsar wind nebulae, binary sources, and Active Galactic Nuclei are all phenomena that reveal particle acceleration through their gamma-ray emission. Diffuse Galactic gamma radiation, Solar System gamma-ray sources, and energetic radiation from supernova remnants are likely tracers of high-energy particle interactions with matter and photon fields. This paper will present a broad overview of the constantly changing sky seen with the Large Area Telescope (LAT) on the Fermi spacecraft.

  11. SAS-2 galactic gamma ray results. 2. Localized sources

    Science.gov (United States)

    Hartman, R. C.; Fichtel, C. E.; Kniffen, D. A.; Lamb, R. C.; Thompson, D. J.; Bignami, G. F.; Oegelman, H.; Oezel, M. E.; Tuemer, T.

    1976-01-01

    Gamma-ray emission was detected from the radio pulsars PSR1818-04 and PSR1747-46, in addition to the previously reported gamma-ray emission from the Crab and Vela pulsars. Since the Crab pulsar is the only one observed in the optical and X-ray bands, these gamma-ray observations suggest a uniquely gamma-ray phenomenon occurring in a fraction of the radio pulsars. Using distance estimates it is found that PSR1818-04 has a gamma-ray luminosity comparable to that of the Crab pulsar, while the luminosities of PSR1747-46 and the Vela pulsar are approximately an order of magnitude lower. This survey of SAS-2 data for pulsar correlations has also yielded upper limits to gamma-ray luminosity for 71 other radio pulsars.

  12. Relation between $\\gamma$-rays and emission lines for the $\\gamma$-ray loud blazars

    CERN Document Server

    Fan, J H

    2000-01-01

    The relation between the $\\gamma$-ray and the emission line luminosities for a sample of 36 $\\gamma$-ray loud blazars is investigated; an apparent correlation between them, $L_{\\gamma} \\propto L_{Line}^{0.69\\pm0.11}$, with a correlation coefficient $r=0.741$ and a chance probability of $p = 1.9\\times10^{-6}$, is found. It is found, however, that there is no intrinsic correlation between them: the apparent correlation is due to the redshift dependence in a flux-limited sample. Thus no evidence is found to support the argument that the up-scattered soft photons are from the broad emission lines. Our analysis does not conflict with the SSC model. The disk-jet symbiosis and radio/$\\gamma$-ray correlation found in the literature are also discussed. The radio/$\\gamma$-ray correlation may be an apparent correlation caused by the boosting effect since both bands are strongly beamed.

  13. Delayed Fission Gamma-ray Characteristics of Th-232 U-233 U-235 U-238 and Pu-239

    Energy Technology Data Exchange (ETDEWEB)

    Lane, Taylor [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Parma, Edward J. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    Delayed fission gamma-rays play an important role in determining the time dependent ioniz- ing dose for experiments in the central irradiation cavity of the Annular Core Research Reactor (ACRR). Delayed gamma-rays are produced from both fission product decay and from acti- vation of materials in the core, such as cladding and support structures. Knowing both the delayed gamma-ray emission rate and the time-dependent gamma-ray energy spectrum is nec- essary in order to properly determine the dose contributions from delayed fission gamma-rays. This information is especially important when attempting to deconvolute the time-dependent neutron, prompt gamma-ray, and delayed gamma-ray contribution to the response of a diamond photo-conducting diode (PCD) or fission chamber in time frames of milliseconds to seconds following a reactor pulse. This work focused on investigating delayed gamma-ray character- istics produced from fission products from thermal, fast, and high energy fission of Th-232, U-233, U-235, U-238, and Pu-239. This work uses a modified version of CINDER2008, a transmutation code developed at Los Alamos National Laboratory, to model time and energy dependent photon characteristics due to fission. This modified code adds the capability to track photon-induced transmutations, photo-fission, and the subsequent radiation caused by fission products due to photo-fission. The data is compared against previous work done with SNL- modified CINDER2008 [ 1 ] and experimental data [ 2 , 3 ] and other published literature, includ- ing ENDF/B-VII.1 [ 4 ]. The ability to produce a high-fidelity (7,428 group) energy-dependent photon fluence at various times post-fission can improve the delayed photon characterization for radiation effects tests at research reactors, as well as other applications.

  14. Pulse Summing in the gamma-Ray Spectra

    CERN Document Server

    Gromov, K Ya; Samatov, Zh K; Chumin, V G

    2004-01-01

    It was shown that the peaks formed at the summing of the cascade gamma-rays pulses can be used for the determination of gamma-ray source activity and gamma-ray registration efficency. Possible sources of the determined quantities errors have been investigated. Such a method can be useful at the nuclear reaction cross section measurements, at background analysis in looking for rare decays and so on.

  15. AGNs and microquasars as high energy gamma-ray sources

    CERN Document Server

    Paredes, J M

    2004-01-01

    The extragalactic analogs of the microquasars, the quasars, are strong gamma-ray emitters at GeV energies. It is expected that microquasars are also gamma-ray sources, because of the analogy with quasars and because theoretical models predict the high-energy emission. There are two microquasars that appear as the possible counterparts for two unidentified high-energy gamma-ray sources.

  16. Gamma ray bursts, neutron star quakes, and the Casimir effect

    CERN Document Server

    Carlson, C; Pérez-Mercader, J; Carlson, C; Goldman, T; Perez-Mercader, J

    1994-01-01

    We propose that the dynamic Casimir effect is a mechanism that converts the energy of neutron starquakes into \\gamma--rays. This mechanism efficiently produces photons from electromagnetic Casimir energy released by the rapid motion of a dielectric medium into a vacuum. Estimates based on the cutoff energy of the gamma ray bursts and the volume involved in a starquake indicate that the total gamma ray energy emission is consonant with observational requirements.

  17. Spectra of {gamma} rays feeding superdeformed bands

    Energy Technology Data Exchange (ETDEWEB)

    Lauritsen, T.; Khoo, T.L.; Henry, R.G. [and others

    1995-08-01

    The spectrum of {gamma}rays coincident with SD transitions contains the transitions which populate the SD band. This spectrum can provide information on the feeding mechanism and on the properties (moment of inertia, collectivity) of excited SD states. We used a model we developed to explain the feeding of SD bands, to calculate the spectrum of feeding {gamma}rays. The Monte Carlo simulations take into account the trigger conditions present in our Eurogam experiment. Both experimental and theoretical spectra contain a statistical component and a broad E2 peak (from transitions occurring between excited states in the SD well). There is good resemblance between the measured and calculated spectra although the calculated multiplicity of an E2 bump is low by {approximately}30%. Work is continuing to improve the quality of the fits, which will result in a better understanding of excited SD states. In addition, a model for the last steps, which cool the {gamma} cascade into the SD yrast line, needs to be developed. A strong M1/E2 low-energy component, which we believe is responsible for this cooling, was observed.

  18. Long Gamma-Ray Transients from Collapsars

    CERN Document Server

    Woosley, S E

    2011-01-01

    In the collapsar model for common gamma-ray bursts, the formation of a centrifugally supported disk occurs during the first $\\sim$10 seconds following the collapse of the iron core in a massive star. This only occurs in a small fraction of massive stellar deaths, however, and requires unusual conditions. A much more frequent occurrence could be the death of a star that makes a black hole and a weak or absent outgoing shock, but in a progenitor that only has enough angular momentum in its outermost layers to make a disk. We consider several cases where this is likely to occur - blue supergiants with low mass loss rates, tidally-interacting binaries involving either helium stars or giant stars, and the collapse to a black hole of very massive pair-instability supernovae. These events have in common the accretion of a solar mass or so of material through a disk over a period much longer than the duration of a common gamma-ray burst. A broad range of powers is possible, $10^{47}$ to $10^{50}\\,$erg s$^{-1}$, and t...

  19. The Cosmic Gamma-Ray Bursts

    CERN Document Server

    Djorgovski, S G; Kulkarni, S R; Sari, R; Bloom, J S; Galama, T J; Harrison, F A; Price, P A; Fox, D; Reichart, D; Yost, S; Berger, E; Diercks, A H; Goodrich, R; Chaffee, F H

    2001-01-01

    Cosmic gamma-ray bursts are one of the great frontiers of astrophysics today. They are a playground of relativists and observers alike. They may teach us about the death of stars and the birth of black holes, the physics in extreme conditions, and help us probe star formation in the distant and obscured universe. In this review we summarise some of the remarkable progress in this field over the past few years. While the nature of the GRB progenitors is still unsettled, it now appears likely that at least some bursts originate in explosions of very massive stars, or at least occur in or near the regions of massive star formation. The physics of the burst afterglows is reasonably well understood, and has been tested and confirmed very well by the observations. Bursts are found to be beamed, but with a broad range of jet opening angles; the mean gamma-ray energies after the beaming corrections are ~ 10^51 erg. Bursts are associated with faint ~ 25 mag) galaxies at cosmological redshifts, with ~ 1. The host gal...

  20. Gamma-ray binaries: pulsars in disguise ?

    CERN Document Server

    Dubus, G

    2006-01-01

    LS 5039 and LSI +61 303 are unique amongst high-mass X-ray binaries (HMXB) for their spatially-resolved radio emission and their counterpart at >GeV gamma-ray energies, canonically attributed to non-thermal particles in an accretion-powered relativistic jet. The only other HMXB known to emit very high energy (VHE) gamma-rays, PSR B1259-63, harbours a non-accreting millisecond pulsar. I investigate whether the interaction of the relativistic wind from a young pulsar with the wind from its stellar companion, as in PSR B1259-63, constitutes a viable scenario to explain the observations of LS 5039 and LSI +61 303. Emission would arise from the shocked pulsar wind material, which then flows away to large distances in a comet-shape tail, reproducing on a smaller scale what is observed in isolated, high motion pulsars interacting with the ISM. Simple expectations for the SED are derived and are shown to depend on few input parameters. Detailed modelling of the particle evolution is compared to the observations from ...

  1. The interplanetary gamma ray burst network

    Science.gov (United States)

    Cline, T.

    The Interplanetary Gamma-Ray Burst Network (IPN) is providing gamma-ray burst (GRB) alerts and localizations at the maximum rate anticipated before the launch of the Swift mission. The arc-minute source precision of the IPN is again permitting searches for GRB afterglows in the radio and optical regimes with delays of only hours up to 2 days. The successful addition of the Mars Odyssey mission has compensated for the loss of the asteroid mission NEAR, to reconstitute a fully long- baseline interplanetary network, with Ulysses at > 5 AU and Konus-Wind and HETE-2 near the Earth. In addition to making unassisted GRB localizations that enable a renewed supply of counterpart observations, the Mars/Ulysses/Wind IPN is confirming and reinforcing GRB source localizations with HETE-2. It has also confirmed and reinforced localizations with the BeppoSAX mission before the BeppoSAX termination in May and has detected and localized both SGRs and an unusual hard x-ray transient that is neither an SGR nor a GRB. This IPN is expected to operate until at least 2004.

  2. Gamma-ray bursts and collisionless shocks

    CERN Document Server

    Waxman, E

    2006-01-01

    Particle acceleration in collisionless shocks is believed to be responsible for the production of cosmic-rays over a wide range of energies, from few GeV to >10^{20} eV, as well as for the non-thermal emission of radiation from a wide variety of high energy astrophysical sources. A theory of collisionless shocks based on first principles does not, however, exist. Observations of gamma-ray burst (GRB) "afterglows" provide a unique opportunity for diagnosing the physics of relativistic collisionless shocks. Most GRBs are believed to be associated with explosions of massive stars, and their "afterglows," delayed low energy emission following the prompt burst of gamma-rays, are produced by relativistic collisionless shock waves driven by the explosion into the surrounding plasma. Some of the striking characteristics of these shocks include the generation of downstream magnetic fields with energy density exceeding that of the upstream field by ~8 orders of magnitude, the survival of this strong field at distances ...

  3. Radio flares from gamma-ray bursts

    CERN Document Server

    Kopac, D; Kobayashi, S; Virgili, F J; Harrison, R; Japelj, J; Guidorzi, C; Melandri, A; Gomboc, A

    2015-01-01

    We present predictions of centimeter and millimeter radio emission from reverse shocks in the early afterglows of gamma-ray bursts with the goal of determining their detectability with current and future radio facilities. Using a range of GRB properties, such as peak optical brightness and time, isotropic equivalent gamma-ray energy and redshift, we simulate radio light curves in a framework generalized for any circumburst medium structure and including a parametrization of the shell thickness regime that is more realistic than the simple assumption of thick- or thin-shell approximations. Building on earlier work by Mundell et al. (2007) and Melandri et al. (2010) in which the typical frequency of the reverse shock was suggested to lie at radio, rather than optical wavelengths at early times, we show that the brightest and most distinct reverse-shock radio signatures are detectable up to 0.1 -- 1 day after the burst, emphasizing the need for rapid radio follow-up. Detection is easier for bursts with later opt...

  4. $\\gamma$-Ray Bursts the Four Crises

    CERN Document Server

    Tavani, M

    1998-01-01

    We discuss some open problems concerning the origin and the emission mechanism of gamma-ray bursts (GRBs) in light of recent developments. If GRBs originate at extragalactic distances, we are facing four crises: (1) an energy crisis, models have to account for more than 10^{53} ergs of energy emitted in the gamma-ray energy band; (2) a spectral crisis, emission models have to account for the surprising `smoothness' of GRB broad-band spectra, with no indication of the predicted spectral `distorsions' caused by inverse Compton scattering in large radiation energy density media, and no evidence for beaming; (3) an afterglow crisis, relativistic shock models have to explain the complexity of the afterglow behavior, the longevity of optical transients detectable up to six months after the burst, the erratic behavior of the radio emission, and the lack of evidence for substantial beaming as indicated by recent searches for GRB afterglows in the X-ray band; (4) a population crisis, from data clearly indicating that ...

  5. Classifying Unidentified Gamma-ray Sources

    CERN Document Server

    Salvetti, David

    2016-01-01

    During its first 2 years of mission the Fermi-LAT instrument discovered more than 1,800 gamma-ray sources in the 100 MeV to 100 GeV range. Despite the application of advanced techniques to identify and associate the Fermi-LAT sources with counterparts at other wavelengths, about 40% of the LAT sources have no a clear identification remaining "unassociated". The purpose of my Ph.D. work has been to pursue a statistical approach to identify the nature of each Fermi-LAT unassociated source. To this aim, we implemented advanced machine learning techniques, such as logistic regression and artificial neural networks, to classify these sources on the basis of all the available gamma-ray information about location, energy spectrum and time variability. These analyses have been used for selecting targets for AGN and pulsar searches and planning multi-wavelength follow-up observations. In particular, we have focused our attention on the search of possible radio-quiet millisecond pulsar (MSP) candidates in the sample of...

  6. Gamma ray tests of Minimal Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Cirelli, Marco [Institut de Physique Théorique, Université Paris Saclay, CNRS, CEA, Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Hambye, Thomas [Service de Physique Theórique, Université Libre de Bruxelles, Boulevard du Triomphe, CP225, 1050 Brussels (Belgium); Panci, Paolo [Institut d’Astrophysique de Paris, UMR 7095 CNRS, Université Pierre et Marie Curie, 98 bis Boulevard Arago, Paris 75014 (France); Sala, Filippo; Taoso, Marco [Institut de Physique Théorique, Université Paris Saclay, CNRS, CEA, Orme des Merisiers, F-91191 Gif-sur-Yvette (France)

    2015-10-12

    We reconsider the model of Minimal Dark Matter (a fermionic, hypercharge-less quintuplet of the EW interactions) and compute its gamma ray signatures. We compare them with a number of gamma ray probes: the galactic halo diffuse measurements, the galactic center line searches and recent dwarf galaxies observations. We find that the original minimal model, whose mass is fixed at 9.4 TeV by the relic abundance requirement, is constrained by the line searches from the Galactic Center: it is ruled out if the Milky Way possesses a cuspy profile such as NFW but it is still allowed if it has a cored one. Observations of dwarf spheroidal galaxies are also relevant (in particular searches for lines), and ongoing astrophysical progresses on these systems have the potential to eventually rule out the model. We also explore a wider mass range, which applies to the case in which the relic abundance requirement is relaxed. Most of our results can be safely extended to the larger class of multi-TeV WIMP DM annihilating into massive gauge bosons.

  7. GRIPS - Gamma-Ray Burst Investigation via Polarimetry and Spectroscopy

    CERN Document Server

    Greiner, J

    2008-01-01

    The primary scientific goal of the GRIPS mission is to revolutionize our understanding of the early universe using gamma-ray bursts. We propose a new generation gamma-ray observatory capable of unprecedented spectroscopy over a wide range of gamma-ray energies (200 keV--50 MeV) and of polarimetry (200--1000 keV). Secondary goals achievable by this mission include direct measurements of supernova interiors through gamma-rays from radioactive decays, nuclear astrophysics with massive stars and novae, and studies of particle acceleration near compact stars, interstellar shocks, and clusters of galaxies.

  8. Fermi Large Area Telescope Bright Gamma-ray Source List

    Energy Technology Data Exchange (ETDEWEB)

    Abdo, Aous A.; /Naval Research Lab, Wash., D.C.; Ackermann, M.; /KIPAC, Menlo Park /SLAC; Ajello, M.; /KIPAC, Menlo Park /SLAC; Atwood, W.B.; /UC, Santa Cruz; Axelsson, M.; /Stockholm U., OKC /Stockholm U.; Baldini, L.; /INFN, Pisa; Ballet, J.; /DAPNIA, Saclay; Band, D.L.; /NASA, Goddard /NASA, Goddard; Barbiellini, Guido; /INFN, Trieste /Trieste U.; Bastieri, Denis; /INFN, Padua /Padua U.; Bechtol, K.; /KIPAC, Menlo Park /SLAC; Bellazzini, R.; /INFN, Pisa; Berenji, B.; /KIPAC, Menlo Park /SLAC; Bignami, G.F.; /Pavia U.; Bloom, Elliott D.; /KIPAC, Menlo Park /SLAC; Bonamente, E.; /INFN, Perugia /Perugia U.; Borgland, A.W.; /KIPAC, Menlo Park /SLAC; Bregeon, J.; /INFN, Pisa; Brigida, M.; /Bari U. /INFN, Bari; Bruel, P.; /Ecole Polytechnique; Burnett, Thompson H.; /Washington U., Seattle /Bari U. /INFN, Bari /KIPAC, Menlo Park /SLAC /IASF, Milan /IASF, Milan /DAPNIA, Saclay /ASDC, Frascati /INFN, Perugia /Perugia U. /KIPAC, Menlo Park /SLAC /George Mason U. /Naval Research Lab, Wash., D.C. /NASA, Goddard /KIPAC, Menlo Park /SLAC /INFN, Perugia /Perugia U. /KIPAC, Menlo Park /SLAC /Montpellier U. /Sonoma State U. /Stockholm U., OKC /Royal Inst. Tech., Stockholm /Stockholm U. /KIPAC, Menlo Park /SLAC /ASDC, Frascati /NASA, Goddard /Maryland U. /Naval Research Lab, Wash., D.C. /INFN, Trieste /Pavia U. /Bari U. /INFN, Bari /KIPAC, Menlo Park /SLAC /UC, Santa Cruz /KIPAC, Menlo Park /SLAC /KIPAC, Menlo Park /SLAC /KIPAC, Menlo Park /SLAC /Montpellier U. /Bari U. /INFN, Bari /Ecole Polytechnique /NASA, Goddard; /more authors..

    2009-05-15

    Following its launch in 2008 June, the Fermi Gamma-ray Space Telescope (Fermi) began a sky survey in August. The Large Area Telescope (LAT) on Fermi in three months produced a deeper and better resolved map of the {gamma}-ray sky than any previous space mission. We present here initial results for energies above 100 MeV for the 205 most significant (statistical significance greater than {approx}10{sigma}) {gamma}-ray sources in these data. These are the best characterized and best localized point-like (i.e., spatially unresolved) {gamma}-ray sources in the early mission data.

  9. Mercuric Iodide Anticoincidence Shield for Gamma-Ray Spectrometer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to utilize a new detector material, polycrystalline mercuric iodide, for background suppression by active anticoincidence shielding in gamma-ray...

  10. Mercuric Iodide Anticoincidence Shield for Gamma-Ray Spectrometer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We utilize a new detector material, polycrystalline mercuric iodide, for background suppression by active anticoincidence shielding in gamma-ray spectrometers. Two...

  11. Possible effects on avionics induced by terrestrial gamma-ray flashes

    Directory of Open Access Journals (Sweden)

    M. Tavani

    2013-04-01

    Full Text Available Terrestrial gamma-ray flashes (TGFs are impulsive (intrinsically sub-millisecond events associated with lightning in powerful thunderstorms. TGFs turn out to be very powerful natural accelerators known to accelerate particles and generate radiation up to hundreds of MeV energies. The number ratio of TGFs over normal lightning has been measured in tropical regions to be near 10−4. We address in this Article the issue of the possible susceptibility of typical aircraft electronics exposed to TGF particle, gamma ray and neutron irradiation. We consider possible scenarios regarding the intensity, the duration, and geometry of TGFs influencing nearby aircraft, and study their effects on electronic equipment. We calculate, for different assumptions, the total dose and the dose-rate, and estimate single-event-effects. We find that in addition to the electromagnetic component (electrons/positrons, gamma rays also secondary neutrons produced by gamma-ray photo production in the aircraft structure substantially contribute to single-event effects in critical semiconductors components. Depending on the physical characteristics and geometry, TGFs may deliver a large flux of neutrons within a few milliseconds in an aircraft. This flux is calculated to be orders of magnitude larger than the natural cosmic-ray background, and may constitute a serious hazard to aircraft electronic equipment. We present a series of numerical simulations supporting our conclusions. Our results suggest the necessity of dedicated measurement campaigns addressing the radiative and particle environment of aircraft near or within thunderstorms.

  12. Dosimetric response of united, commercially available CTA foils for sup 6 sup 0 Co gamma rays

    CERN Document Server

    Peimel-Stuglik, Z

    2001-01-01

    The usefulness of two kinds of untinted CTA foils: Fuji CTR-125 dosimetric foil and technical CTA-T foil, produced by 'Zaklady Chemiczne, 'Gorzow Wielkopolski' as support for light-sensitive layers of amateur photo-films, for sup 6 sup 0 Co gamma ray dosimetry was investigated. In spite of rather bad physical parameters of the technical foil (spread of foil thickness, high and different initial absorbance) the dosimetric response of both foils for sup 6 sup 0 Co gamma rays was similar. The CTA-T foil can be used for routine dosimetry providing that dosimetric signals have to be calculated exactly as recommended by the ASTM (American Society for Testing and Materials) standard, i.e. as the difference of absorbance of irradiated and (the same) non-irradiated foil. Any other approach may lead to high errors of dose evaluation. The last is true also for other CTA foils, especially after long self-life.

  13. Effective atomic numbers of blue topaz at different gamma-rays energies obtained from Compton scattering technique

    Energy Technology Data Exchange (ETDEWEB)

    Tuschareon, S., E-mail: tuscharoen@hotmail.com; Limkitjaroenporn, P., E-mail: tuscharoen@hotmail.com; Kaewkhao, J., E-mail: tuscharoen@hotmail.com [Center of Excellence in Glass Technology and Materials Science (CEGM), Nakhon Pathom Rajabhat University, Nakhon Pathom, 73000, Thailand and Science Program, Faculty of Science and Technology, Nakhon Pathom Rajabhat University, Nakhon Pathom, 73000 (Thailand)

    2014-03-24

    Topaz occurs in a wide range of colors, including yellow, orange, brown, pink-to-violet and blue. All of these color differences are due to color centers. In order to improve the color of natural colorless topaz, the most commonly used is irradiated with x- or gamma-rays, indicated that attenuation parameters is important to enhancements by irradiation. In this work, the mass attenuation coefficients of blue topaz were measured at the different energy of γ-rays using the Compton scattering technique. The results show that, the experimental values of mass attenuation coefficient are in good agreement with the theoretical values. The mass attenuation coefficients increase with the decrease in gamma rays energies. This may be attributed to the higher photon interaction probability of blue topaz at lower energy. This result is a first report of mass attenuation coefficient of blue topaz at different gamma rays energies.

  14. 60Co辐射交联乙烯-醋酸乙烯酯共聚物/氢氧化镁复合材料的热、力学及阻燃性能研究%Thermal, mechanical and flame-retardant properties of crosslinked ethylene vinyl-acetate copolymer/magnesium hydroxide blends by 60Co irradiation

    Institute of Scientific and Technical Information of China (English)

    李振中; 何伟; 张文熊; 瞿保钧

    2007-01-01

    Three types of ethylene vinyl-acetate copolymer (EVA)/magnesium hydroxide (MH) blends were crosslinked by 60Co γ-irradiation in the presence of trimethylolpropane triacrylate. The influences of irradiation dose on the crosslinking degree and thermal, mechanical and flame retardant properties of EVA/MH blends were studied through the measurements of gel content, Vicat point, limiting oxygen index (LOI), UL-94, tensile testing and the thermogravimetric analysis (TGA). The test results show that the EVA/MH blend with higher vinyl-acetate content in EVA is easier to be crosslinked. The thermal distortion resistance, mechanical and flame-retardant properties of EVA/MH blends are obviously improved by 60Co irradiation. The TGA shows that the thermal stabilities of EVA/MH blends are apparently affected by 60Co γ-irradiation.%以三羟甲基丙烷三丙烯酸酯为交联助剂,以60Co为辐射源,对三种不同醋酸乙烯酯(Vinyl-acetate,VA)含量的乙烯-醋酸乙烯酯共聚物(Ethylene vinyl-acetate copolymer,EVA)/氢氧化镁混合材料进行了辐照交联.通过对凝胶含量、维卡软化点、氧指数、UL-94垂直燃烧和拉伸性能的测试及热重分析,研究了辐照剂量对EVA/氢氧化镁交联体的交联度、热性能、力学性能和阻燃性能的影响.研究结果表明:VA含量高的EVA/氢氧化镁交联体更容易产生辐射交联;辐照交联后的EVA/氢氧化镁复合材料的抗热变形能力、力学性能及阻燃性能都获得明显改善.热重分析结果表明,60Co辐射明显影响EVA/氢氧化镁的热氧稳定性.

  15. Physico chemical and microbiological changes in nopal (Opuntia spp.) irradiated with gamma rays of cobalt 60; Cambios fisicoquimicos y microbiologicos en nopal (Opuntia spp.) irradiado con rayos gamma de cobalto 60

    Energy Technology Data Exchange (ETDEWEB)

    Perez N, M

    2001-07-01

    The objective of this work is to study the physico-chemical and microbiological changes which take place in the nopal (Opuntia spp.) after they have been irradiated and stored at environment and refrigeration temperatures in order to determine the level of irradiation dose more adequate for getting them an increase in the storage life, as well as to determine the physico-chemical changes attributed to the irradiation doses used, comparing the obtained results with those ones of non-irradiated nopal samples, which are considered as control samples. The radiation source used was a GAMMABEAM-651 PT, property of the Nuclear Sciences Institute of UNAM. The nopals studied are of the variety (Milpa Alta, Opuntia ficus) which were cut and packed in polyethylene bags with and without nitrogen. In order to find the adequate dose level it was used a lot of 200 samples which were treated in sets of 10. They were irradiated in doses of 0.5 to 10 kGy at a dose reason of 3.7 kGy/h. The adequate doses for getting an increase in the storage life, where there was not darkness were of 1.5 and 2.0 kGy, allowed doses in the NOM-033-SSA1-1993, it was not found any change in acceptability by flavour, but so in the titled activity values and sugars. The lowest loss of weight was found in the 1.5 kGy dose without nitrogen and the highest in the 2.0 kGy with nitrogen dose. Likewise was determined that with the irradiation treatment in the recommended doses it is diminished the microorganisms growth, obtaining an improvement in the general appearance of the nopals during their storage period. (Author)

  16. The Gamma Ray Bursts Hubble diagram

    CERN Document Server

    Capozziello, S; Dainotti, M G; De Laurentis, M; Izzo, L; Perillo, M

    2011-01-01

    Thanks to their enormous energy release, Gamma Rays Bursts (GRBs) have recently attracted a lot of interest to probe the Hubble diagram (HD) deep into the matter dominated era and hence complement Type Ia Supernovae (SNeIa). We consider here three different calibration methods based on the use of a fiducial LCDM model, on cosmographic parameters and on the local regression on SNeIa to calibrate the scaling relations proposed as an equivalent to the Phillips law to standardize GRBs finding any significant dependence. We then investigate the evolution of these parameters with the redshift to obtain any statistical improvement. Under this assumption, we then consider possible systematics effects on the HDs introduced by the calibration method, the averaging procedure and the homogeneity of the sample arguing against any significant bias.

  17. Search for Gamma Ray Bursts at Chacaltaya

    CERN Document Server

    Vernetto, S

    2001-01-01

    A search for Gamma Ray Bursts in the GeV-TeV energy range has been performed by INCA, an air shower array working at 5200 m of altitude at the Chacaltaya Laboratory (Bolivia). The altitude of the detector and the use of the "single particle technique" allows to lower the energy threshold up to few GeVs. No significant signals are observed during the occurrence of 125 GRBs detected by BATSE, and the obtained upper limits on the energy fluence in the interval 1-1000(100) GeV range from 3.2(8.6) 10^-5 to 2.6(7.0) 10^-2 erg/cm^2 depending on the zenith angle of the events. These limits, thanks to the extreme altitude of INCA, are the lowest ever obtained in the sub-TeV energy region by a ground based esperiment.

  18. Black Holes, Supernovae and Gamma Ray Bursts

    CERN Document Server

    Ruffini, Remo

    2013-01-01

    We review recent progress in our understanding of the nature of gamma ray bursts (GRBs) and in particular, of the relationship between short GRBs and long GRBs. The first example of a short GRB is described. The coincidental occurrence of a GRB with a supernova (SN) is explained within the induced gravitational collapse (IGC) paradigm, following the sequence: 1) an initial binary system consists of a compact carbon-oxygen (CO) core star and a neutron star (NS); 2) the CO core explodes as a SN, and part of the SN ejecta accretes onto the NS which reaches its critical mass and collapses to a black hole (BH) giving rise to a GRB; 3) a new NS is generated by the SN as a remnant. The observational consequences of this scenario are outlined.

  19. Gamma-ray Production in Supernova Remnants

    CERN Document Server

    Baring, M G

    1997-01-01

    Supernova remnants are widely believed to be a principal source of galactic cosmic rays, produced by diffusive shock acceleration in the environs of the remnant's expanding shock. This review discusses recent modelling of how such energetic particles can produce gamma-rays via interactions with the remnants' ambient interstellar medium, specifically via neutral pion decay, bremsstrahlung and inverse Compton emission. Predictions that relate to the handful of associations between EGRET unidentified sources and known radio/optical/X-ray emitting remnants are summarized. The cessation of acceleration above 1 TeV - 10 TeV energies in young shell-type remnants is critical to model consistency with Whipple's TeV upper limits; these observations provide important diagnostics for theoretical models.

  20. Relativistic Outflows in Gamma-Ray Bursts

    CERN Document Server

    Aloy, M A

    2007-01-01

    The possibility that gamma-ray bursts (GRBs) were not isotropic emissions was devised theoretically as a way to ameliorate the huge energetic budget implied by the standard fireball model for these powerful phenomena. However, the mechanism by which after the quasy-isotropic release of a few $10^{50} $erg yields a collimated ejection of plasma could not be satisfactory explained analytically. The reason being that the collimation of an outflow by its progenitor system depends on a very complex and non-linear dynamics. That has made necessary the use of numerical simulations in order to shed some light on the viability of some likely progenitors of GRBs. In this contribution I will review the most relevant features shown by these numerical simulations and how they have been used to validate the collapsar model (for long GRBs) and the model involving the merger of compact binaries (for short GRBs).

  1. Balloon-borne gamma-ray polarimetry

    CERN Document Server

    Pearce, Mark

    2011-01-01

    The physical processes postulated to explain the high-energy emission mechanisms of compact astrophysical sources often yield polarised soft gamma rays (X-rays). PoGOLite is a balloon-borne polarimeter operating in the 25-80 keV energy band. The polarisation of incident photons is reconstructed using Compton scattering and photoelectric absorption in an array of phoswich detector cells comprising plastic and BGO scintillators, surrounded by a BGO side anticoincidence shield. The polarimeter is aligned to observation targets using a custom attitude control system. The maiden balloon flight is scheduled for summer 2011 from the Esrange Space Centre with the Crab and Cygnus X-1 as the primary observational targets.

  2. Statistics of gamma ray burst temporal asymmetry

    CERN Document Server

    Link, B; Link, Bennett; Epstein, Richard

    1996-01-01

    We study the temporal asymmetry of over 600 bursts from the BATSE 3B catalog, encompassing a 200-fold range in peak flux. By comparing the rates of rise and fall of the flux near the highest burst peak, we find that about two-thirds of the bursts exhibit a preferred asymmetry in the sense that the flux rises more rapidly than it falls, confirming the conclusions of previous studies employing smaller databases. The statistical significance of the average time asymmetry of the sample is >99.999\\%; therefore, models that predict time symmetry of the burst profile are ruled out. We find no statistically significant correlation between burst temporal asymmetry and peak. This result is consistent with both cosmological and local interpretations of the gamma ray burst phenomenon.

  3. Perspectives on Gamma-Ray Pulsar Emission

    CERN Document Server

    Baring, Matthew G

    2010-01-01

    Pulsars are powerful sources of radiation across the electromagnetic spectrum. This paper highlights some theoretical insights into non-thermal, magnetospheric pulsar gamma-ray radiation. These advances have been driven by NASA's Fermi mission, launched in mid-2008. The Large Area Telescope (LAT) instrument on Fermi has afforded the discrimination between polar cap and slot gap/outer gap acceleration zones in young and middle-aged pulsars. Altitude discernment using the highest energy pulsar photons will be addressed, as will spectroscopic interpretation of the primary radiation mechanism in the LAT band, connecting to both polar cap/slot gap and outer gap scenarios. Focuses will mostly be on curvature radiation and magnetic pair creation, including population trends that may afford probes of the magnetospheric accelerating potential.

  4. Critical Test Of Gamma Ray Burst Theories

    CERN Document Server

    Dado, Shlomo

    2016-01-01

    Long and precise follow-up measurements of the X-ray afterglow (AG) of very intense gamma ray bursts (GRBs) provide a critical test of GRB afterglow theories. Here we show that the power-law decline with time of X-ray AG of GRB 130427A, the longest measured X-ray AG of an intense GRB with the Swift, Chandra and XMM Newton sat