WorldWideScience

Sample records for 4c obs survey

  1. Integrated geophysical interpretation of the Valhall 4C OBS survey

    Energy Technology Data Exchange (ETDEWEB)

    Thomsen, Leon A.; Barkved, Olav I; Mueller, Michael C.; Haggard, Bill W.; Kommedal, Jan H.; Rosland, Boerge O.

    1998-12-31

    This presentation gives a brief classic example of a North Sea reservoir which cannot be imaged by conventional P-wave techniques. In two-dimensional P-wave sections, extending across the crest of the structure, the top of the chalk reservoir is depressed in time, and has low amplitude and coherency so that even its identification is uncertain. The classical interpretation of these effects is that, over geologic time, gas has leaked from the reservoir into the overburden, in the zone above the reservoir. This gas, while present in uneconomic concentrations, has the effect of lowering seismic velocities and increasing seismic attenuation. Efficient methods of seismic surveying were used for oil prediction in the reservoir. 6 refs.

  2. The B Fields in OB Stars (BOB) Survey

    CERN Document Server

    Morel, T; Fossati, L; Hubrig, S; Langer, N; Przybilla, N; Scholler, M; Carroll, T; Ilyin, I; Irrgang, A; Oskinova, L; Schneider, F R N; Diaz, S Simon; Briquet, M; Gonzalez, J F; Kharchenko, N; Nieva, M -F; Scholz, R -D; de Koter, A; Hamann, W -R; Herrero, A; Apellaniz, J Maiz; Sana, H; Arlt, R; Barba, R; Dufton, P; Kholtygin, A; Mathys, G; Piskunov, A; Reisenegger, A; Spruit, H; Yoon, S -C

    2014-01-01

    The B fields in OB stars (BOB) survey is an ESO large programme collecting spectropolarimetric observations for a large number of early-type stars in order to study the occurrence rate, properties, and ultimately the origin of magnetic fields in massive stars. As of July 2014, a total of 98 objects were observed over 20 nights with FORS2 and HARPSpol. Our preliminary results indicate that the fraction of magnetic OB stars with an organised, detectable field is low. This conclusion, now independently reached by two different surveys, has profound implications for any theoretical model attempting to explain the field formation in these objects. We discuss in this contribution some important issues addressed by our observations (e.g., the lower bound of the field strength) and the discovery of some remarkable objects.

  3. The Chandra Cygnus OB2 Legacy Survey: Design and X-ray Point Source Catalog

    CERN Document Server

    Wright, Nicholas J; Guarcello, Mario G; Aldcroft, Tom L; Kashyap, Vinay L; Damiani, Francesco; DePasquale, Joe; Fruscione, Antonella

    2014-01-01

    The Cygnus OB2 association is the largest concentration of young and massive stars within 2 kpc of the Sun, including an estimated 65 O-type stars and hundreds of OB stars. The Chandra Cygnus OB2 Legacy Survey is a large imaging program undertaken with the Advanced CCD Imaging Spectrometer onboard the Chandra X-ray Observatory. The survey has imaged the central 0.5 deg^2 of the Cyg OB2 association with an effective exposure of 120ks and an outer 0.35 deg^2 area with an exposure of 60ks. Here we describe the survey design and observations, the data reduction and source detection, and present a catalog of 8,000 X-ray point sources. The survey design employs a grid of 36 heavily (~50%) overlapping pointings, a method that overcomes Chandra's low off-axis sensitivity and produces a highly uniform exposure over the inner 0.5 deg^2. The full X-ray catalog is described here and is made available online.

  4. Technical development and scientific preparation for the e-MERLIN Cygnus OB2 radio survey

    OpenAIRE

    Peck, L. W.

    2014-01-01

    e-MERLIN is a recent upgrade to the MERLIN radio array. This enhanced facility utilises recent developments in wide bandwidth receivers, a new WIDAR correlator, and a new optical fibre network. This upgrade provides an increase in sensitivity and image fidelity, but also results in a significant increase in data volume. This thesis is motivated by the Cygnus OB2 Radio Survey (COBRaS), an e-MERLIN Legacy project observing the core region of the largest OB association in the northern hemisphere...

  5. VizieR Online Data Catalog: Fourth Cambridge Survey (4C) (Pilkington+ 1965; Gower+ 1967)

    Science.gov (United States)

    Pilkington, J. D. H.; Scott, P. F.

    1996-04-01

    The Fourth Cambridge Radio Survey (4C) Catalogue contains all survey data from the papers of Pilkington and Scott (1965MmRAS..69..183P) and Gower, Scott and Wills (1967MmRAS..71...49G). These data result from a survey of radio sources between declinations -07 and +80 degrees using the large Cambridge interferometer at 178 MHz. The computerized catalog contains for each source the 4C number, 1950 position, measured flux density, accuracy class, galactic coordinates, and remarks. For some sources miscellaneous brief comments such as cross identifications to the 3C catalog or remarks on contamination from nearby sources are given at the ends of the data records. A flag (*) is included if there are additional remarks in the published catalog. (1 data file).

  6. The CIDA Variability Survey of Orion OB1. I: the low-mass population of Ori OB 1a and 1b

    CERN Document Server

    Briceño, C; Hernández, J; Vivas, A K; Hartmann, L; Downes, J J; Berlind, P; Briceno, Cesar; Calvet, Nuria; Hernandez, Jesus; Hartmann, Lee; Downes, Juan J.; Berlind, Perry

    2004-01-01

    We present results of a large scale, multi-epoch optical survey of the Ori OB1 association, carried out with the QuEST camera at the Venezuela National Astronomical Observatory. We identify for the first time the widely spread low-mass, young population in the Orion OB1a and OB1b sub-associations. Candidate members were picked up by their variability in the V-band and position in color-magnitude diagrams. We obtained spectra to confirm membership. In a region spanning ~ 68 deg^2 we found 197 new young stars; of these, 56 are located in the Ori OB1a subassociation and 142 in Ori OB1b. Comparison with the spatial extent of molecular gas and extinction maps indicates that the subassociation Ori 1b is concentrated within a ring-like structure of radius ~2 deg (~15 pc at 440 pc), centered roughly on the star epsilon Ori in the Orion belt. The ring is apparent in 13CO and corresponds to a region with an extinction Av>=1. The stars exhibiting strong Ha emission, an indicator of active accretion, are found along this...

  7. The deep OB star population in Carina from the VST Photometric H$\\alpha$ Survey (VPHAS+)

    CERN Document Server

    Mohr-Smith, M; Napiwotzki, R; Simón-Díaz, S; Wright, N J; Barentsen, G; Eislöffel, J; Farnhill, H J; Greimel, R; Monguió, M; Kalari, V; Parker, Q A; Vink, J S

    2016-01-01

    Massive OB stars are critical to the ecology of galaxies, and yet our knowledge of OB stars in the Milky Way, fainter than $V \\sim 12$, remains patchy. Data from the VST Photometric H$\\alpha$ Survey (VPHAS+) permit the construction of the first deep catalogues of blue excess-selected OB stars, without neglecting the stellar field. A total of 14900 candidates with 2MASS cross-matches are blue-selected from a 42 square-degree region in the Galactic Plane, capturing the Carina Arm over the Galactic longitude range $282^{\\circ} \\lesssim \\ell \\lesssim 293^{\\circ}$. Spectral energy distribution fitting is performed on these candidates' combined VPHAS+ $u,g,r,i$ and 2MASS $J,H,K$ magnitudes. This delivers: effective temperature constraints, statistically separating O from early-B stars; high-quality extinction parameters, $A_0$ and $R_V$ (random errors typically $ 3.5$) extinction laws are ubiquitous in the region, over the distance range 2.5--3 kpc to $\\sim$10~kpc. Near prominent massive clusters, $R_V$ tends to ri...

  8. Massive open star clusters using the VVV survey. V. Young clusters with an OB stellar population

    Science.gov (United States)

    Ramírez Alegría, S.; Borissova, J.; Chené, A.-N.; Bonatto, C.; Kurtev, R.; Amigo, P.; Kuhn, M.; Gromadzki, M.; Carballo-Bello, J. A.

    2016-04-01

    Context. The ESO public survey VISTA Variables in the Vía Láctea (VVV) has contributed with deep multi-epoch photometry of the Galactic bulge and the adjacent part of the disk over 526 sq. deg. More than a hundred cluster candidates have been reported thanks to this survey. Aims: We present the fifth article in a series of papers focused on young and massive clusters discovered in the VVV survey. In this paper, we present the physical characterization of five clusters with a spectroscopically confirmed OB-type stellar population. Methods: To characterize the clusters, we used near-infrared photometry (J, H, and KS) from the VVV survey and near-infrared K-band spectroscopy from ISAAC at VLT, following the methodology presented in the previous articles of the series. Results: All clusters in our sample are very young (ages between 1-20 Myr), and their total mass are between (1.07+0.40-0.30)×102 M⊙ and (4.17+4.15-2.08)×103 M⊙. We observed a relation between the clusters total mass Mecl and the mass of their most massive stellar member mmax, for clusters with an age <10 Myr. Based on observations taken within the ESO VISTA Public Survey VVV (programme ID 179.B-2002), and with ISAAC/VLT (programme 087.D-0341(A)).

  9. Massive open star clusters using the VVV survey V. Young clusters with an OB stellar population

    CERN Document Server

    Alegría, S Ramírez; Chené, A -N; Bonatto, C; Kurtev, R; Amigo, P; Kuhn, M; Gromadzki, M; Carballo-Bello, J A

    2016-01-01

    The ESO public survey VISTA Variables in the V\\'ia L\\'actea (VVV) has contributed with deep multi-epoch photometry of the Galactic bulge and the adjacent part of the disk over 526 square degrees. More than a hundred cluster candidates have been reported thanks to this survey. We present the fifth article in a series of papers focused on young and massive clusters discovered in the VVV survey. In this paper, we present the physical characterization of five clusters with a spectroscopically confirmed OB-type stellar population. To characterize the clusters, we used near-infrared photometry ($J$, $H,$ and $K_S$) from the VVV survey and near-infrared $K$-band spectroscopy from ISAAC at VLT, following the methodology presented in the previous articles of the series. All clusters in our sample are very young (ages between 1-20 Myr), and their total mass are between $(1.07^{+0.40}_{-0.30})\\cdot10^2$ $M_{\\odot}$ and $(4.17^{+4.15}_{-2.08})\\cdot10^3$ $M_{\\odot}$. We observed a relation between the clusters total mass ...

  10. New massive X-ray binary candidates from the ROSAT Galactic Plane Survey I - Results from a cross-correlation with OB star catalogues

    OpenAIRE

    Motch, C.; Haberl, F.; Dennerl, K.; Pakull, M.; Janot-Pacheco, E.

    1996-01-01

    We report the discovery of several new OB/X-ray accreting binary candidates. These massive systems were found by cross-correlating in position SIMBAD OB star catalogues with the part of the ROSAT all-sky survey located at low galactic latitudes (|b| 10^31 erg/s. Fol...

  11. Infrared properties of Active OB stars in the Magellanic Clouds from the Spitzer SAGE Survey

    OpenAIRE

    Bonanos, A. Z.; Lennon, D.J.; Massa, D. L.; Sewilo, M.; Köhlinger, F.; Panagia, N.; van Loon, J. Th.; Evans, C. J.; Smith, L J; Meixner, M.; Gordon, K; teams, the SAGE

    2010-01-01

    We present a study of the infrared properties of 4922 spectroscopically confirmed massive stars in the Large and Small Magellanic Clouds, focusing on the active OB star population. Besides OB stars, our sample includes yellow and red supergiants, Wolf-Rayet stars, Luminous Blue Variables (LBVs) and supergiant B[e] stars. We detect a distinct Be star sequence, displaced to the red, and find a higher fraction of Oe and Be stars among O and early-B stars in the SMC, respectively, when compared t...

  12. Toward Complete Statistics of Massive Binary Stars: Penultimate Results from the Cygnus OB2 Radial Velocity Survey

    CERN Document Server

    Kobulnicky, Henry A; Lundquist, Michael J; Burke, Jamison; Chapman, James; Keller, Erica; Lester, Kathryn; Rolen, Emily K; Topel, Eric; Bhattacharjee, Anirban; Smullen, Rachel A; Alvarez, Carlos A Vargas; Runnoe, Jessie C; Dale, Daniel A; Brotherton, Michael M

    2014-01-01

    We analyze orbital solutions for 48 massive multiple-star systems in the Cygnus OB2 Association, 23 of which are newly presented here, to find that the observed distribution of orbital periods is approximately uniform in log P for P 45 d, even after correction for completeness, indicating either a lower binary fraction or a shift toward low-mass companions. A high degree of similarity (91% likelihood) between the Cyg OB2 period distribution and that of other surveys suggests that the binary properties at P<25 d are determined by local physics of disk/clump fragmentation and are relatively insensitive to environmental and evolutionary factors. Fully 30% of the unbiased parent sample is a binary with period P < 45 d. Completeness corrections imply a binary fraction near 55% for P < 5000 d. The observed distribution of mass ratios 0.2

  13. Toward Complete Statistics of Massive Binary Stars: Penultimate Results from the Cygnus OB2 Radial Velocity Survey

    Science.gov (United States)

    Kobulnicky, Henry A.; Kiminki, Daniel C.; Lundquist, Michael J.; Burke, Jamison; Chapman, James; Keller, Erica; Lester, Kathryn; Rolen, Emily K.; Topel, Eric; Bhattacharjee, Anirban; Smullen, Rachel A.; Vargas Álvarez, Carlos A.; Runnoe, Jessie C.; Dale, Daniel A.; Brotherton, Michael M.

    2014-08-01

    We analyze orbital solutions for 48 massive multiple-star systems in the Cygnus OB2 association, 23 of which are newly presented here, to find that the observed distribution of orbital periods is approximately uniform in log P for P power law provides a statistically compelling prescription, but if features are ignored, a power law with exponent β ~= -0.22 provides a crude approximation over P = 1.4-2000 days, as does a piece-wise linear function with a break near 45 days. The cumulative period distribution flattens at P > 45 days, even after correction for completeness, indicating either a lower binary fraction or a shift toward low-mass companions. A high degree of similarity (91% likelihood) between the Cyg OB2 period distribution and that of other surveys suggests that the binary properties at P period P < 45 days. Completeness corrections imply a binary fraction near 55% for P < 5000 days. The observed distribution of mass ratios 0.2 < q < 1 is consistent with uniform, while the observed distribution of eccentricities 0.1 < e < 0.6 is consistent with uniform plus an excess of e ~= 0 systems. We identify six stars, all supergiants, that exhibit aperiodic velocity variations of ~30 km s-1 attributed to atmospheric fluctuations.

  14. TOWARD COMPLETE STATISTICS OF MASSIVE BINARY STARS: PENULTIMATE RESULTS FROM THE CYGNUS OB2 RADIAL VELOCITY SURVEY

    International Nuclear Information System (INIS)

    We analyze orbital solutions for 48 massive multiple-star systems in the Cygnus OB2 association, 23 of which are newly presented here, to find that the observed distribution of orbital periods is approximately uniform in log P for P < 45 days, but it is not scale-free. Inflections in the cumulative distribution near 6 days, 14 days, and 45 days suggest key physical scales of ≅0.2, ≅0.4, and ≅1 A.U. where yet-to-be-identified phenomena create distinct features. No single power law provides a statistically compelling prescription, but if features are ignored, a power law with exponent β ≅ –0.22 provides a crude approximation over P = 1.4-2000 days, as does a piece-wise linear function with a break near 45 days. The cumulative period distribution flattens at P > 45 days, even after correction for completeness, indicating either a lower binary fraction or a shift toward low-mass companions. A high degree of similarity (91% likelihood) between the Cyg OB2 period distribution and that of other surveys suggests that the binary properties at P ≲ 25 days are determined by local physics of disk/clump fragmentation and are relatively insensitive to environmental and evolutionary factors. Fully 30% of the unbiased parent sample is a binary with period P < 45 days. Completeness corrections imply a binary fraction near 55% for P < 5000 days. The observed distribution of mass ratios 0.2 < q < 1 is consistent with uniform, while the observed distribution of eccentricities 0.1 < e < 0.6 is consistent with uniform plus an excess of e ≅ 0 systems. We identify six stars, all supergiants, that exhibit aperiodic velocity variations of ∼30 km s–1 attributed to atmospheric fluctuations

  15. TOWARD COMPLETE STATISTICS OF MASSIVE BINARY STARS: PENULTIMATE RESULTS FROM THE CYGNUS OB2 RADIAL VELOCITY SURVEY

    Energy Technology Data Exchange (ETDEWEB)

    Kobulnicky, Henry A.; Lundquist, Michael J.; Burke, Jamison; Chapman, James; Keller, Erica; Lester, Kathryn; Rolen, Emily K.; Topel, Eric; Bhattacharjee, Anirban; Smullen, Rachel A.; Álvarez, Carlos A. Vargas; Runnoe, Jessie C.; Dale, Daniel A.; Brotherton, Michael M. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82070 (United States); Kiminki, Daniel C., E-mail: chipk@uwyo.edu, E-mail: jburke2@swarthmore.edu, E-mail: jc6380@mcla.edu, E-mail: kelle22e@mtholyoke.edu, E-mail: kvl214@lehigh.edu, E-mail: emily.k.rolen@vanderbilt.edu, E-mail: topel@stolaf.edu [Department of Astronomy, University of Arizona, Tucson, AZ 85721 (United States)

    2014-08-01

    We analyze orbital solutions for 48 massive multiple-star systems in the Cygnus OB2 association, 23 of which are newly presented here, to find that the observed distribution of orbital periods is approximately uniform in log P for P < 45 days, but it is not scale-free. Inflections in the cumulative distribution near 6 days, 14 days, and 45 days suggest key physical scales of ≅0.2, ≅0.4, and ≅1 A.U. where yet-to-be-identified phenomena create distinct features. No single power law provides a statistically compelling prescription, but if features are ignored, a power law with exponent β ≅ –0.22 provides a crude approximation over P = 1.4-2000 days, as does a piece-wise linear function with a break near 45 days. The cumulative period distribution flattens at P > 45 days, even after correction for completeness, indicating either a lower binary fraction or a shift toward low-mass companions. A high degree of similarity (91% likelihood) between the Cyg OB2 period distribution and that of other surveys suggests that the binary properties at P ≲ 25 days are determined by local physics of disk/clump fragmentation and are relatively insensitive to environmental and evolutionary factors. Fully 30% of the unbiased parent sample is a binary with period P < 45 days. Completeness corrections imply a binary fraction near 55% for P < 5000 days. The observed distribution of mass ratios 0.2 < q < 1 is consistent with uniform, while the observed distribution of eccentricities 0.1 < e < 0.6 is consistent with uniform plus an excess of e ≅ 0 systems. We identify six stars, all supergiants, that exhibit aperiodic velocity variations of ∼30 km s{sup –1} attributed to atmospheric fluctuations.

  16. Long-Baseline Interferometric Multiplicity Survey of the Sco-Cen OB Association

    CERN Document Server

    Rizzuto, A C; Robertson, J G; Kok, Y; Tuthill, P G; Warrington, B A; Haubois, X; Tango, W J; Norris, B; Brummelaar, T ten; Kraus, A L; Jacob, A; Laliberte-Houdeville, C

    2013-01-01

    We present the first multiplicity-dedicated long baseline optical interferometric survey of the Scorpius-Centaurus-Lupus-Crux association. We used the Sydney University Stellar Interferometer to undertake a survey for new companions to 58 Sco-Cen B- type stars and have detected 24 companions at separations ranging from 7-130mas, 14 of which are new detections. Furthermore, we use a Bayesian analysis and all available information in the literature to determine the multiplicity distribution of the 58 stars in our sample, showing that the companion frequency is F = 1.35 and the mass ratio distribution is best described as a power law with exponent equal to -0.46, agreeing with previous Sco-Cen high mass work and differing significantly from lower-mass stars in Tau-Aur. Based on our analysis, we estimate that among young B-type stars in moving groups, up to 23% are apparently single stars. This has strong implications for the understanding of high-mass star formation, which requires angular momentum dispersal thr...

  17. Extinctions and Distances to Dark Clouds from 2MASS, MegaCam and IPHAS Surveys: LDN 1525 in the Direction of the Aur OB1 Association

    Science.gov (United States)

    Straižys, V.; Drew, J. E.; Laugalys, V.

    The possibility of applying photometry from the 2MASS J, H, Ks, MegaCam u, g and IPHAS r, i, Hα surveys for determining the distance to the dark cloud LDN 1525 (TGU 1192) in the direction of the Aur OB1 association is investigated using the red clump giants. The main dust cloud, probably related to the emission nebulae Sh 2-232, Sh 2-233, Sh 2-235, the molecular cloud and the association Aur OB2, is found to be located at a distance of 1.3 kpc from the Sun. The nebula Sh 2-231 can be an object of the Perseus arm. The maximum extinction AV found in the cloud is close to 6 mag.

  18. Documentation for the machine-readable version of the Fourth Cambridge Radio Survey Catalogue (4C) (Pilkington, Gower, Scott and Wills 1965, 1967)

    Science.gov (United States)

    Warren, W. H., Jr.

    1983-09-01

    The machine readable catalogue contains survey data from the papers of Pilkington and Scott and Gower, Scott and Wills. These data result from a survey of radio sources between declinations -07 deg and +80 deg using the large Cambridge interferometer at 178 MHz. The computerized catalog contains for each source the 4C number, 1950 position, measured flux density, and accuracy class. For some sources miscellaneous brief comments such as cross identifications to the 3C catalog or remarks on contamination from nearby sources are given at the ends of the data records. A detailed description of the machine readable catalog as it is currently being distributed by the Astronomical Data Center is given to enable users to read and process the data.

  19. The VLT-FLAMES Tarantula Survey XVI. The optical+NIR extinction laws in 30 Doradus and the photometric determination of the effective temperatures of OB stars

    CERN Document Server

    Apellániz, J Maíz; Barbá, R H; Gräfener, G; Bestenlehner, J M; Crowther, P A; García, M; Herrero, A; Sana, H; Simón-Díaz, S; Taylor, W D; van Loon, J Th; Vink, J S; Walborn, N R

    2014-01-01

    Context: The commonly used extinction laws of Cardelli et al. (1989) have limitations that, among other issues, hamper the determination of the effective temperatures of O and early B stars from optical+NIR photometry. Aims: We aim to develop a new family of extinction laws for 30 Doradus, check their general applicability within that region and elsewhere, and apply them to test the feasibility of using optical+NIR photometry to determine the effective temperature of OB stars. Methods: We use spectroscopy and NIR photometry from the VLT-FLAMES Tarantula Survey and optical photometry from HST/WFC3 of 30 Doradus and we analyze them with the software code CHORIZOS using different assumptions such as the family of extinction laws. Results: We derive a new family of optical+NIR extinction laws for 30 Doradus and confirm its applicability to extinguished Galactic O-type systems. We conclude that by using the new extinction laws it is possible to measure the effective temperatures of OB stars with moderate uncertain...

  20. The VLT-FLAMES Tarantula Survey. XVI. The optical and NIR extinction laws in 30 Doradus and the photometric determination of the effective temperatures of OB stars

    Science.gov (United States)

    Maíz Apellániz, J.; Evans, C. J.; Barbá, R. H.; Gräfener, G.; Bestenlehner, J. M.; Crowther, P. A.; García, M.; Herrero, A.; Sana, H.; Simón-Díaz, S.; Taylor, W. D.; van Loon, J. Th.; Vink, J. S.; Walborn, N. R.

    2014-04-01

    Context. The commonly used extinction laws of Cardelli et al. (1989, ApJ, 345, 245) have limitations that, among other issues, hamper the determination of the effective temperatures of O and early B stars from optical and near-infrared (NIR) photometry. Aims: We aim to develop a new family of extinction laws for 30 Doradus, check their general applicability within that region and elsewhere, and apply them to test the feasibility of using optical and NIR photometry to determine the effective temperature of OB stars. Methods: We use spectroscopy and NIR photometry from the VLT-FLAMES Tarantula Survey and optical photometry from HST/WFC3 of 30 Doradus and we analyze them with the software code CHORIZOS using different assumptions, such as the family of extinction laws. Results: We derive a new family of optical and NIR extinction laws for 30 Doradus and confirm its applicability to extinguished Galactic O-type systems. We conclude that by using the new extinction laws it is possible to measure the effective temperatures of OB stars with moderate uncertainties and only a small bias, at least up to E(4405-5495) ~ 1.5 mag. Appendices are available in electronic form at http://www.aanda.org

  1. The OBS Survey of Seismogenic Processes: Using 2010 Chile M=8.8 Mega Earthquake as example

    Science.gov (United States)

    Lee, C.; Wei, H.; Wang, S.

    2012-12-01

    In the early morning of February 27, 2010, a mega-earthquake now known as the "Maule Earthquake" (M=8.8) took place in central Chile. In May 1960, Chile was hit by the largest earthquake ever recorded with a magnitude of 9.5. In general, the west coast of Chile is a convergent boundary between the Nazca and South American Plates, with the Nazca Plate subducting beneath the South American Plate in a NE direction. With a convergence rate of 6-7 cm per year, stress accumulates in the lower part of the oceanic plate to a certain extent resulting in huge destructive earthquakes. In 2010, our team deployed two OBS arrays (the A and B arrays), with a total of 33 deployments to record the aftershocks along the rupture area. We collected data for a total of 46 days (July 15 to August 7 for the A array and August 14 to September 6 for the B array). The aim of our study was to analyze the distribution and characteristics of the aftershocks to get a better understanding of the tectonic activity after the main event, and conjecture on the seismogenic processes that occurred during the rupture. Using the Antelope software on the data we picked the P- and S-wave arrivals and located the events. To obtain more accurate earthquake epicenter locations we also applied the HypoDD software. We recognized a total of 3,807 events in 46 days of monitoring (in average of 80 some earthquakes per day) with many of them distributed along both sides of the trench. Immediately behind the trench axis, along the frontal accretionary prism, there is an aseismic zone, possibly due to the high content of water in the sedimentary strata. On the other hand, the paleo-accretionary prism on the landward side of the trench accumulated most of the earthquakes. These events focus at depths of 50-100 km in the subduction zone. This is called the seismogenic zone. The comparison of events before the main shock and the HypoDD results of this study show that most of the events cluster along the edge of the

  2. The Bolocam Galactic Plane Survey -- III. Characterizing Physical Properties of Massive Star-Forming Regions in the Gemini OB1 Molecular Cloud

    CERN Document Server

    Dunham, Miranda K; Evans, Neal J; Cyganowski, Claudia J; Aguirre, James; Bally, John; Battersby, Cara; Bradley, Eric Todd; Dowell, Darren; Drosback, Meredith; Ginsburg, Adam; Glenn, Jason; Harvey, Paul; Merello, Manuel; Schlingman, Wayne; Shirley, Yancy L; Stringfellow, Guy S; Walawender, Josh; Williams, Jonathan P

    2010-01-01

    We present the 1.1 millimeter Bolocam Galactic Plane Survey (BGPS) observations of the Gemini OB1 molecular cloud complex, and targeted ammonia observations of the BGPS sources. When paired with molecular spectroscopy of a dense gas tracer, millimeter observations yield physical properties such as masses, radii, mean densities, kinetic temperatures and line widths. We detect 34 distinct BGPS sources above 5-sigma=0.37 Jy/beam with corresponding 5-sigma detections in the ammonia (1,1) transition. Eight of the objects show water maser emission (20%). We find a mean millimeter source FWHM of 1.12 pc, and a mean kinetic temperature of 20 K for the sample of 34 BGPS sources. The observed ammonia line widths are dominated by non-thermal motions, typically found to be a few times the thermal sound speed expected for the derived kinetic temperature. We calculate the mass for each source from the millimeter flux assuming the sources are isothermal and find a mean isothermal mass within a 120" aperture of 230 +/- 180 s...

  3. The 4C model

    DEFF Research Database (Denmark)

    Knox, Jeanette Bresson Ladegaard

    2014-01-01

    Doctors and nurses at the neonatal intensive-care unit at The University Hospital, Rigshospitalet, in Copenhagen, Denmark regularly find themselves in ethically challenging and potentially distressing situations concerning the life of ill newborn babies. In collaboration with the neonatal intensi...... how the 4C model was developed and whereof it consists....

  4. Balanced {C_4, C_5}-Quatrefoil Systems

    OpenAIRE

    Ushio, Kazuhiko

    2004-01-01

    In graph theory, the decomposition problems of graphs are very important topics. Various types of decompositions of many graphs can be seen in the literature of gaph theory. We give the necessary and sufficient condition for the existence of a balanced {C_4, C_5}-quatrefoil decomposition of K_n for each of (C_4, C_4, C_4, C_4)-quatrefoil, (C_4, C_4, C_4, C_5)-quatrefoil, (C_4, C_4, C_5, C_5)-quatrefoil, (C_4, C_5, C_5, C_5)-quatrefoil, and (C_5, C_5, C_5, C_5)-quatrefoil. These decompositions...

  5. Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice

    Science.gov (United States)

    Wang, Xianfeng; Buechler, Nancy L.; Martin, Ayana; Wells, Jonathan; Yoza, Barbara; McCall, Charles E.; Vachharajani, Vidula

    2016-01-01

    Objective Obesity increases morbidity and resource utilization in sepsis patients. Sepsis transitions from early/hyper-inflammatory to late/hypo-inflammatory phase. Majority of sepsis-mortality occurs during the late sepsis; no therapies exist to treat late sepsis. In lean mice, we have shown that sirtuins (SIRTs) modulate this transition. Here, we investigated the role of sirtuins, especially the adipose-tissue abundant SIRT-2 on transition from early to late sepsis in obese with sepsis. Methods Sepsis was induced using cecal ligation and puncture (CLP) in ob/ob mice. We measured microvascular inflammation in response to lipopolysaccharide/normal saline re-stimulation as a “second-hit” (marker of immune function) at different time points to track phases of sepsis in ob/ob mice. We determined SIRT-2 expression during different phases of sepsis. We studied the effect of SIRT-2 inhibition during the hypo-inflammatory phase on immune function and 7-day survival. We used a RAW264.7 (RAW) cell model of sepsis for mechanistic studies. We confirmed key findings in diet induced obese (DIO) mice with sepsis. Results We observed that the ob/ob-septic mice showed an enhanced early inflammation and a persistent and prolonged hypo-inflammatory phase when compared to WT mice. Unlike WT mice that showed increased SIRT1 expression, we found that SIRT2 levels were increased in ob/ob mice during hypo-inflammation. SIRT-2 inhibition in ob/ob mice during the hypo-inflammatory phase of sepsis reversed the repressed microvascular inflammation in vivo via activation of endothelial cells and circulating leukocytes and significantly improved survival. We confirmed the key finding of the role of SIRT2 during hypo-inflammatory phase of sepsis in this project in DIO-sepsis mice. Mechanistically, in the sepsis cell model, SIRT-2 expression modulated inflammatory response by deacetylation of NFκBp65. Conclusion SIRT-2 regulates microvascular inflammation in obese mice with sepsis and may

  6. e-MERLIN 21 cm constraints on the mass-loss rates of OB stars in Cyg OB2

    Science.gov (United States)

    Morford, J. C.; Fenech, D. M.; Prinja, R. K.; Blomme, R.; Yates, J. A.

    2016-11-01

    We present e-MERLIN 21 cm (L-band) observations of single luminous OB stars in the Cygnus OB2 association, from the Cyg OB2 Radio Survey Legacy programme. The radio observations potentially offer the most straightforward, least model-dependent, determinations of mass-loss rates, and can be used to help resolve current discrepancies in mass-loss rates via clumped and structured hot star winds. We report here that the 21 cm flux densities of O3 to O6 supergiant and giant stars are less than ˜70 μJy. These fluxes may be translated to `smooth' wind mass-loss upper limits of ˜4.4-4.8 × 10-6 M⊙ yr -1 for O3 supergiants and ≲2.9 × 10-6 M⊙ yr -1 for B0 to B1 supergiants. The first ever resolved 21 cm detections of the hypergiant (and luminous blue variable candidate) Cyg OB2 #12 are discussed; for multiple observations separated by 14 d, we detect an ˜69 per cent increase in its flux density. Our constraints on the upper limits for the mass-loss rates of evolved OB stars in Cyg OB2 support the model that the inner wind region close to the stellar surface (where Hα forms) is more clumped than the very extended geometric region sampled by our radio observations.

  7. Disk evolution in the Ori OB1 association

    CERN Document Server

    Calvet, N; Hernández, J; Hoyer, S; Hartmann, L; Sicilia-Aguilar, A; Megeath, S T; D'Alessio, P; Calvet, Nuria; Briceno, Cesar; Hernandez, Jesus; Hoyer, Sergio; Hartmann, Lee; Sicilia-Aguilar, Aurora; Alessio, Paola D'

    2004-01-01

    We analyze multi-band photometry of a subsample of low mass stars in the associations Ori OB1a and 1b discovered during the CIDA Orion Variability Survey, which have ages of 7 - 10 Myr and 3 - 5 Myr, respectively. We obtained UBVRcIc photometry at Mt. Hopkins for 6 Classical T Tauri stars (CTTS) and 26 Weak T Tauri stars (WTTS) in Ori OB1a, and for 21 CTTS and 2 WTTS in Ori OB1b. We also obtained L band photometry for 14 CTTS at Mt. Hopkins, and 10um and 18um photometry with OSCIR at Gemini for 6 CTTS; of these, all 6 were detected at 10um while only one was detected at 18um. We estimate mass accretion rates from the excess luminosity at U, and find that they are consistent with determinations for a number of other associations, with or without high mass star formation. The observed decrease of mass accretion rate with age is qualitatively consistent with predictions of viscous evolution of accretion disks. We find an overall decrease of disk emission from Taurus to Ori OB1b to Ori OB1a. This decrease implies...

  8. Chandra observations of Cygnus OB2

    CERN Document Server

    Wright, Nicholas J; Drew, Janet E; Vink, Jorick S

    2011-01-01

    Cygnus OB2 is the nearest example of a massive star forming region, containing over 50 O-type stars and hundreds of B-type stars. We have analyzed two Chandra pointings in Cyg OB2, detecting ~1700 X-ray sources, of which ~1450 are thought to be members of the association. Optical and near-IR photometry has been obtained for ~90% of these sources from recent deep Galactic plane surveys. We have performed isochrone fits to the near-IR color-magnitude diagram, deriving ages of 3.5(+0.75,-1.0) and 5.25(+1.5,-1.0) Myrs for sources in the two fields, both with considerable spreads around the pre-MS isochrones. The presence of a second population in the region, somewhat older than the present-day O-type stars, has been suggested by other authors and fits with the ages derived here. The fraction of sources with inner circumstellar disks (as traced by the K-band excess) is found to be very low, but appropriate for a population of age ~5 Myrs. We measure the stellar mass functions and find a power-law slope of Gamma = ...

  9. A Search for Pulsar Companions to OB Runaway Stars

    Science.gov (United States)

    Sayer, R. W.; Nice, D. J.; Kaspi, V. M.

    1996-04-01

    We have searched for radio pulsar companions to 40 nearby OB runaway stars. Observations were made at 575 and 770 MHz with the NRAO 140 foot (43 m) telescope. The survey was sensitive to long- period pulsars with flux densities of 1 mJy or more. No pulsar companions to OB runaways were discovered. One previously unknown pulsar was discovered, PSR J2044 +4614, while observing toward target 0 star BD +45°3260. Follow-up timing observations of the pulsar measured its position to high precision, revealing a 9' separation between the pulsar and the target star, unequivocally indicating they are not associated. The pulsar is ordinary, except that its dispersion measure, 315 pc cm-3, is unusually high given its Galactic longitude, l = 85°. The nondetection of pulsars bound to target stars places an upper limit of 8% (95% confidence) for the fraction of runaway OB stars with pulsar companions detectable via pulsed radio emission by surveys such as ours. Assuming standard models for the pulsar beaming fraction and luminosity function, we conclude most OB runaways do not have pulsar companions.

  10. Progress of homemade OBS and its application on ocean bottom structure survey%国产海底地震仪研制现状及其在海底结构探测中的应用

    Institute of Scientific and Technical Information of China (English)

    郝天珧; 游庆瑜

    2011-01-01

    海底地震仪(Ocean Bottom Seismographs,OBS)及由其组成的海底流动地震观测台阵是近年来发展起来的高新技术,在油气探测、科学研究、防灾减灾等方面有广泛的用途,是地球物理仪器与探测技术发展中的一个新增长点.本文介绍了由中国科学院地质与地球物理研究所研制成功的宽频带、7通道海底地震仪((I-7C) OBS)的性能、指标以及关键技术的实现.同时,介绍了(I-7C) OBS近年来在渤海、南海以及西南印度洋的5次海上试验与应用的结果.5次应用试验中均有国外同类型的一起参加,(I-7C) OBS在性能指标、回收率和数据质量等方面都有较好的表现.2010年以来,国产OBS在我国各海区经过上百台次的海上作业(超过半数工作水深在2000m以上),仅丢失一台.仪器回收率超过98%,数据完整率超过950%.一些航次的首席科学家认为我国国产OBS已经达到国际先进水平.%Ocean Bottom Seismographs (OBS) and the seabed mobile seismic observation array composed by them was recently developed high-tech. It s a new growth point in the geophysical instruments and exploration technology, and it has a wide range of uses, such as in oil and gas exploration, scientific research, disaster prevention and mitigation and so on. The performance, technical data, and key techniques of the I-7C Ocean Bottom Seismograph (OBS) is introduced in this paper. The wideband 7-channel OBS is designed and produced by Institute of Geology and Geophysics, Chinese Academy of Sciences. In recent years we have conducted five marine tests in the Bohai Sea, South China Sea, and southwestern Indian Ocean. OBS instruments made in western countries were also used in the five tests. The results indicate the good performance of the (I-7C) OBS in technical data, recovery operation ratio, and data quality. Since 2010,homemade OBS were tested over one hundred times in different seas, more than half worked in over 2000 meters

  11. Black Rice with Giant Embryo Attenuates Obesity-Associated Metabolic Disorders in ob/ob Mice.

    Science.gov (United States)

    Lee, Yoon-Mi; Han, Sank-Ik; Won, Yu-Jin; Lee, Eunji; Park, Eunju; Hwang, Seock-Yeon; Yeum, Kyung-Jin

    2016-03-30

    Obesity is closely associated with metabolic disorders such as hyperglycemia and dyslipidemia. Leptin-deficient ob/ob mice (C57BL/6J-ob/ob) and C57BL/6J mice were randomly assigned to a diet of black rice with giant embryo (BR), white rice (WR), or AIN-93G (control) and pair-fed for 14 weeks. Although there was no significant difference in body weight, BR-fed ob/ob mice had (1) significantly lower body fat mass than WR- and control-fed ob/ob mice determined by dual-energy X-ray absorptiometry; (2) significantly lower blood glucose, serum insulin, and triacylglycerol levels than control-fed ob/ob mice; and (3) significantly lower liver weight, hepatic triacylglycerol, and hepatic lipid droplets than both WR- and control-fed ob/ob mice. Furthermore, DNA damage in the liver, determined by phosphorylated H2AX protein, and in the kidney, determined by single-cell gel electrophoresis, was significantly lower in BR-fed than WR- and control-fed ob/ob mice. This study indicates that BR ameliorates obesity and its related metabolic disorders. PMID:26653400

  12. Refraction Interferometry and Free-surface Multiples for Large-offset OBS Data

    Science.gov (United States)

    Schuster, G. T.; Bharadwaj, P.; McIntosh, K.

    2011-12-01

    We present successful results for applying refraction interferometry to ocean bottom seismic (OBS) data. The OBS data were recorded by six inline OBS stations with a 15 km station spacing and a source ship shooting every 150 meters; the maximum source offset from an OBS station is 181 km. Each virtual trace was created by correlating and stacking up to 150 trace pairs to create a super-virtual refraction arrival having a theoretical signal-to-noise ratio (SNR) enhancement of up to 12:1. Free-surface refraction multiples were also utilized to enhance the SNR of primary refractions and virtually double the number of OBS sites from six to twelve stations. Results show the successful reconstruction of far-offset traces out to a source-receiver offset of 120 km. The super-virtual traces increase the number of pickable first arrivals from approximately 1,600 to more than 3,100 for a subset of the OBS data where the source is only on one side of the recording stations. In addition, the head waves associated with the first-order free-surface multiples allow for the creation of six new common receiver gathers (CRGs) recorded at virtual OBS stations, located about 5 km from any of the actual OBS stations. These new traces double the number of OBS stations compared to the original survey and increases the number of pickable traces from 1600 to 6200. In summary, our results with this OBS data set demonstrate that refraction interferometry can more than triple the number of pickable first arrivals in long-offset traces. This suggests the possibility that the number of independent OBS stations can be increased by N-fold if the free-surface refraction multiples up to the Nth-order are of high SNR and if the recording time is appropriately lengthened.

  13. The Nearest OB Association: Scorpius-Centaurus (Sco OB2)

    CERN Document Server

    Preibisch, Thomas

    2008-01-01

    We summarize observational results on the stellar population and star formation history of the Scorpius-Centaurus OB Association (Sco OB2), the nearest region of recent massive star formation. It consists of three subgroups, Upper Scorpius (US), Upper Centaurus-Lupus (UCL), and Lower Centaurus-Crux (LCC) which have ages of about 5, 17, and 16 Myr. In Upper Scorpius, numerous studies have recently revealed hundreds of low-mass association members, including dozens of brown dwarfs. The empirical mass function could be established over the full stellar mass range from 0.1 M_sun up to 20 M_sun, and was found to be consistent with recent determinations of the field initial mass function. A narrow range of ages around 5 Myr was found for the low-mass stars, the same age as had previously (and independently) been derived for the high-mass members. This supports earlier indications that the star formation process in US was triggered, and agrees with previous conjectures that the triggering event was a supernova- and ...

  14. New OBS network deployment offshore Ireland

    Science.gov (United States)

    Le Pape, Florian; Bean, Chris; Craig, David; Jousset, Philippe; Horan, Clare; Hogg, Colin; Donne, Sarah; McCann, Hannah; Möllhoff, Martin; Kirk, Henning; Ploetz, Aline

    2016-04-01

    With the presence of the stormy NE Atlantic, Ireland is ideally located to investigate further our understanding of ocean generated microseisms and use noise correlation methods to develop seismic imaging in marine environments as well as time-lapse monitoring. In order to study the microseismic activity offshore Ireland, 10 Broad Band Ocean Bottom Seismographs (OBSs) units including hydrophones have been deployed in January 2016 across the shelf offshore Donegal and out into the Rockall Trough. This survey represents the first Broadband passive study in this part of the NE Atlantic. The instruments will be recovered in August 2016 providing 8 months worth of data to study microseisms but also the offshore seismic activity in the area. One of the main goal of the survey is to investigate the spatial and temporal distributions of dominant microseism source regions, close to the microseism sources. Additionally we will study the coupling of seismic and acoustic signals at the sea bed and its evolution in both the deep water and continental shelf areas. Furthermore, the survey also aims to investigate further the relationship between sea state conditions (e.g. wave height, period), seafloor pressure variations and seismic data recorded on both land and seafloor. Finally, the deployed OBS network is also the first ever attempt to closely monitor local offshore earthquakes in Ireland. Ireland seismicity although relatively low can reduce slope stability and poses the possibility of triggering large offshore landslides and local tsunamis.

  15. ZAZNANO TVEGANJE OB SPLETNEM NAKUPOVANJU

    OpenAIRE

    Mihurko, Kaja

    2011-01-01

    Zaradi številnih prednosti, ki jih splet nudi, se število spletnih trgovin iz dneva v dan nenehno veča. Poznavanje vedenja kupcev pomaga izvajalcem marketinga pri prodobivanju in zaržanju kupcev. Zelo pomembno je tudi to, da se izvajalci marketinga zavedajo vloge, ki jo ima zaznavanje tveganje ob spletnem nakupovanju. V prvem teoretičnem delu je opisan pomen in prednosti spletnega poslovanja ter spletnega nakupovanja. Drugi del govori o vedenju kupcev na spletu, zadnji del pa o tveganju, ...

  16. The Dynamics of an Expanding OB Association

    CERN Document Server

    Wright, Nicholas J; Drake, Jeremy J; Drew, Janet E; Guarcello, Mario; Navacues, David Barrado y

    2012-01-01

    We present 3-dimensional kinematical observations of the massive OB association Cygnus OB2 to identify the mechanisms responsible for disrupting young star clusters. The picture revealed by these observations is of a highly-substructured, dynamically unmixed OB association that does not exhibit the position-velocity correlations predicted by the theories of infant mortality or tidal stripping. These observations would appear to support a picture of hierarchical star formation.

  17. MULTIWAVELENGTH SYSTEMATICS OF OB SPECTRA

    Directory of Open Access Journals (Sweden)

    Nolan R. Walborn

    2008-01-01

    Full Text Available La sistematica de los espectros OB es resumida, en el rango optico dominado por líneas fotosféricas, y en el lejano ultravioleta (tanto de IUE como de FUSE donde dominan perfiles de los vientos estelares. Primero, las tendencias bidimensionales (temperatura, luminosidad en los espectros normales son examinadas. Luego, establecida la estructura de referencia normal, se pueden reconocer relativo a ésta varias categorías de objetos peculiares, las cuales revelan sendos fenómenos de importancia estructural y/o evolutiva. Se incluyen anomalías de CNO en tipos O tempranos y tardíos, tres variedades de rotadores rápidos, objetos de transición Of/WN de alta y baja temperatura, y la recientemente descubierta segunda estrella magnética de tipo O conocida. Aunque se han adelantado y se siguen adelantando las interpretaciones físicas de estas tendencias y anomalías, mayor atención al modelaje de la sistemática aceleraría el progreso a futuro en la opinión de este autor. Finalmente, se presentan resultados preliminares de un estudio con Chandra en alta resolución de los espectros OB en el rangode rayos X. Éstos proveen evidencias de que, tal como sucedió anteriormente en el UV, tendencias morfológicas sistemáticas existen en el dominio de rayos X, las cuales son correlacionadas con los tipos espectrales ´opticos, y de allá con los parámetros estelares fundamentales, al contrario de la opinión especialista prevaleciente.

  18. 南海西南次海盆与南沙地块的OBS探测和地壳结构%OBS survey and crustal structure of the Southwest Sub-basin and Nansha Block, South China Sea

    Institute of Scientific and Technical Information of China (English)

    丘学林; 赵明辉; 敖威; 吕川川; 郝天珧; 游庆瑜; 阮爱国; 李家彪

    2011-01-01

    跨越南海西南次海盆南部陆缘和南沙地块中部的OBS973-1测线是南海南部首次采集的海底地震仪(OBS)广角反射与折射深地震测线,本文通过震相分析和走时正演拟合,获得了沿测线的二维纵波速度结构模型.模拟结果显示表层沉积物速度2.5~4.5 km/s,厚度1000~3000m,局部基底面起伏较大.结晶基底的速度从顶部的4.5~5.5 km/s增加到地壳底部的6.8~6.9 km/s,中地壳有一个小的速度不连续面(0.1~0.2 km/s),而地壳底部的莫霍面有较大的速度反差(1.2 km/s),上地幔顶部的速度为8.0~8.1 km/s.莫霍面埋深和地壳厚度在测线的北段和南段有很大的不同,在测线北段的海盆区,莫霍面埋深约11 km,结晶地壳的厚度仅为5~6 km,表现为典型洋壳的特征,而在测线南段的陆块区,莫霍面埋深最大达24 km,地壳厚度可达20 km,表现为减薄陆壳的特征,从海盆区到陆块区莫霍面埋深和地壳厚度迅速增加.陆块区上下地壳的厚度和变化趋势相似,下地壳没有看到高速层(HVL),可能说明地壳内部是以纯剪拉张的均匀减薄为主,地壳下部的岩浆底侵不发育.对比OBS973-2和OBS973-3测线的结构模型,可以推测南沙地块的中部和东部具有相似的构造性质,西南次海盆两侧是一对非火山型的不对称共轭陆缘.%OBS973-1 is a wide angle reflection and refraction deep seismic line using Ocean Bottom Seismometers (OBS) , deployed for the first time in the southern part of South China Sea. The line crosses the southern margin of the Southwest Sub-basin and the middle part of Nansha Block. By seismic phase analysis and travel time fitting, a 2D P-wave velocity model along theline is constructed. The modeling results show that the surface sedimentary layer has a velocity of 2. 5~4. 5 km/s and a thickness of 1000~ 3000m, with locally rough basement interface. The crystalline basement has a velocity of 4. 5~5. 5 km/s on the top, increasing to

  19. Impaired Muscle Regeneration in Ob/ob and Db/db Mice

    Directory of Open Access Journals (Sweden)

    Mai-Huong Nguyen

    2011-01-01

    Full Text Available In obesity and type 2 diabetes, efficient skeletal muscle repair following injury may be required, not only for restoring muscle structure and function, but also for maintaining exercise capacity and insulin sensitivity. The hypothesis of this study was that muscle regeneration would be impaired in ob/ob and db/db mice, which are common mouse models of obesity and type 2 diabetes. Muscle injury was produced by cardiotoxin injection, and regeneration was assessed by morphological and immunostaining techniques. Muscle regeneration was delayed in ob/ob and db/db mice, but not in a less severe model of insulin resistance – feeding a high-fat diet to wild-type mice. Angiogenesis, cell proliferation, and myoblast accumulation were also impaired in ob/ob and db/db mice, but not the high-fat diet mice. The impairments in muscle regeneration were associated with impaired macrophage accumulation; macrophages have been shown previously to be required for efficient muscle regeneration. Impaired regeneration in ob/ob and db/db mice could be due partly to the lack of leptin signaling, since leptin is expressed both in damaged muscle and in cultured muscle cells. In summary, impaired muscle regeneration in ob/ob and db/db mice was associated with reduced macrophage accumulation, angiogenesis, and myoblast activity, and could have implications for insulin sensitivity in the skeletal muscle of obese and type 2 diabetic patients.

  20. HSL Attenuates the Follicular Oxidative Stress and Enhances the Hair Growth in ob/ob Mice

    Directory of Open Access Journals (Sweden)

    Takeo Minematsu, PhD

    2013-10-01

    Full Text Available Summary: We demonstrated enhanced hair regeneration following topical administration of N-(3-oxododecanoyl-L-homoserine lactone (HSL in ob/ob mice. The ob/ob mice showed delayed hair regeneration (more than 6 wk after depilation, which rapidly induced transition to anagen in the hair cycle in wild-type mice. Vehicle and HSL solutions were applied to the depilated dorsal skin of ob/ob mice. The depilated skin of the HSL-treated mice was fully covered with hair, whereas no macroscopic alteration was observed in vehicle-treated group by the fourth week after depilation. Oxidative stress was drastically decreased and the expression of the antioxidative enzymes PON1 and PON3 was increased in the HSL-treated skin with highly proliferative anagen follicles. These results suggest that HSL is a candidate therapeutic agent for alopecia in metabolic syndrome.

  1. Serotonin transporter (SERT and translocator protein (TSPO expression in the obese ob/ob mouse

    Directory of Open Access Journals (Sweden)

    Santini Ferruccio

    2011-02-01

    Full Text Available Abstract Background An ever growing body of evidences is emerging concerning metabolism hormones, neurotransmitters or stress-related biomarkers as effective modulators of eating behavior and body weight in mammals. The present study sought at examining the density and affinity of two proteins related to neurotransmission and cell metabolism, the serotonin transporter SERT and the cholesterol import-benzodiazepine site TSPO (translocator protein, in a rodent leptin-lacking mutant, the obese ob/ob mouse. Binding studies were thus carried out in brain or peripheral tissues, blood platelets (SERT and kidneys (TSPO, of ob/ob and WT mice supplied with a standard diet, using the selective radiochemical ligands [3H]-paroxetine and [3H]-PK11195. Results We observed comparable SERT number or affinity in brain and platelets of ob/ob and WT mice, whilst a significantly higher [3H]-PK11195 density was reported in the brain of ob/ob animals. TSPO binding parameters were similar in the kidneys of all tested mice. By [3H]-PK11195 autoradiography of coronal hypothalamic-hippocampal sections, an increased TSPO signal was detected in the dentate gyrus (hippocampus and choroids plexus of ob/ob mice, without appreciable changes in the cortex or hypothalamic-thalamic regions. Conclusions These findings show that TSPO expression is up-regulated in cerebral regions of ob/ob leptin-deficient mice, suggesting a role of the translocator protein in leptin-dependent CNS trophism and metabolism. Unchanged SERT in mutant mice is discussed herein in the context of previous literature as the forerunner to a deeper biochemical investigation.

  2. PHOTOEVAPORATING PROPLYD-LIKE OBJECTS IN CYGNUS OB2

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Nicholas J.; Drake, Jeremy J.; Guarcello, Mario G.; Hora, Joseph L. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Drew, Janet E. [Centre for Astronomy Research, Science and Technology Research Institute, University of Hertfordshire, Hatfield AL10 9AB (United Kingdom); Gutermuth, Robert A. [Department of Astronomy, University of Massachusetts, Amherst, MA (United States); Kraemer, Kathleen E., E-mail: nwright@cfa.harvard.edu [Boston College, Institute for Scientific Research, 140 Commonwealth Avenue, Chestnut Hill, MA 02467 (United States)

    2012-02-20

    We report the discovery of 10 proplyd-like objects in the vicinity of the massive OB association Cygnus OB2. They were discovered in IPHAS H{alpha} images and are clearly resolved in broadband Hubble Space Telescope/Advanced Camera for Surveys, near-IR, and Spitzer mid-IR images. All exhibit the familiar tadpole shape seen in photoevaporating objects such as the Orion proplyds, with a bright ionization front at the head facing the central cluster of massive stars and a tail stretching in the opposite direction. Many also show secondary ionization fronts, complex tail morphologies, or multiple heads. We consider the evidence that these are either proplyds or 'evaporating gaseous globules' (EGGs) left over from a fragmenting molecular cloud, but find that neither scenario fully explains the observations. Typical sizes are 50,000-100,000 AU, larger than the Orion proplyds, but in agreement with the theoretical scaling of proplyd size with distance from the ionizing source. These objects are located at projected separations of {approx}6-14 pc from the OB association, compared to {approx}0.1 pc for the Orion proplyds, but are clearly being photoionized by the {approx}65 O-type stars in Cyg OB2. Central star candidates are identified in near- and mid-IR images, supporting the proplyd scenario, though their large sizes and notable asymmetries are more consistent with the EGG scenario. A third possibility is therefore considered that these are a unique class of photoevaporating partially embedded young stellar objects that have survived the destruction of their natal molecular cloud. This has implications for the properties of stars that form in the vicinity of massive stars.

  3. Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme

    OpenAIRE

    Hilzendeger, A.M.; da Costa Goncalves, A.C.; Plehm, R.; Diedrich, A.; Gross, V; J.B. Pesquero; Bader, M

    2010-01-01

    The leptin-deficient ob/ob mice are insulin resistant and obese. However, the control of blood pressure in this model is not well defined. The goal of this study was to evaluate the role of leptin and of the renin-angiotensin system in the cardiovascular abnormalities observed in obesity using a model lacking leptin. To this purpose, we measured blood pressure in ob/ob and control animals by radiotelemetry combined with fast Fourier transformation before and after both leptin and enalapril tr...

  4. OBS development and data analysis in Taiwan

    Science.gov (United States)

    Lin, C.; Wang, C.; Chen, P.; Chang, H.; Jang, J.; Kuo, B.

    2012-12-01

    Since 1991 there have been various types of ocean bottom seismometers (OBS) deployed in the waters around Taiwan with different scientific goals. A few years of experiences taught us that many aspects of the instruments can be improved without too much effort. These include extension of deployment time, extension of the recording bandwidth of a short period OBS, and more flexibly to accommodate scientific demands without instrumental overhaul. Scientists will not burden themselves by these tasks, and sending back the instrument to original manufactory for modifications is usually impractical budget-wise, in timeline, and for mission goals. It is thus necessary to develop a sustainable OBS program in Taiwan. Academia Sinica has been collaborating with Taiwan Ocean Research Institute (TORI) and National Sun Yat-sen University (NSYSU) to build a new short-period OBS which has passed a series of tests and have been deployed in the Okinawa trough, Bashi channel, east Korea offshore and on service in Huatung basin. This paper describes the design goal of this OBS, component specification, and reports the preliminary analyses of data and the future directions of instrument development. Keywords: Ocean bottom seismometer, OBS

  5. On the Performance of Fixed Burst Length OBS

    Institute of Scientific and Technical Information of China (English)

    Seung-Woo; Seo

    2003-01-01

    In this paper, we propose a new OBS scheme, named Fixed Burst Length OBS. The FBL-OBS networks, combined with the extra-offset time scheme, can guarantee the QoS of OBS networks in a more efficient way.

  6. Neural Network Pruning Algorithm with Penalty OBS Process

    Institute of Scientific and Technical Information of China (English)

    MENG Jiang; WANG Yao-cai; LIU Tao

    2005-01-01

    Aimed at the great computing complexity of optimal brain surgeon (OBS) process, a pruning algorithm with penalty OBS process is presented. Compared with sensitive and regularized methods, the penalty OBS algorithm not only avoids time-consuming defect and low pruning efficiency in OBS process, but also keeps higher generalization and pruning accuracy than Levenberg-Marquardt method.

  7. K-band spectroscopy of deeply embedded, young OB stars

    OpenAIRE

    Bik, A.; Kaper, L.; Hanson, M.M.; Waters, L. B. F. M.

    2006-01-01

    We have obtained high resolution (R = 10,000) K-band spectra of candidate young massive stars deeply embedded in high-mass star-forming regions. These objects were selected from a near-infrared survey of 44 regions of high-mass star-formation (Kaper et al, 2006). In these clusters, 38 OB stars are identified whose K-band spectra are dominated by photospheric emission. In almost all those stars, the K-band spectra are indistinguishable from field stars. However, in some stars the profile of th...

  8. Post-T Tauri Stars in the Nearest OB Association

    CERN Document Server

    Mamajek, E E; Liebert, J; Mamajek, Eric E.; Meyer, Michael R.; Liebert, James

    2002-01-01

    We present results of a spectroscopic survey of X-ray- and proper motion-selected samples of late-type stars in the Lower Cen-Cru (LCC) and Upper Cen-Lup (UCL) subgroups of the nearest OB association: Sco-Cen. The primary goals of the survey are to determine the star-formation history of the OB subgroups, and to assess the frequency of accreting stars in a sample dominated by ``post-T Tauri'' pre-MS stars. We investigate two samples: (1) ACT and TRC proper motion candidates with X-ray counterparts in the ROSAT All-Sky Survey BSC, and (2) G and K-type Hipparcos candidate members (de Zeeuw et al. 1999). We obtained optical spectra of 130 candidates with the MSSSO 2.3-m DBS. Pre-MS stars were identified by (1) strong Li 6707A absorption, (2) subgiant surface gravities, (3) proper motions consistent with Sco-Cen membership, and (4) HRD positions consistent with being pre-MS. We demonstrate that measuring the gravity-sensitive band-ratio of Sr II 4077A to Fe I 4071A is a valuable means of discriminating pre-MS and...

  9. Leptin differentially regulate STAT3 activation in ob/ob mouse adipose mesenchymal stem cells

    Directory of Open Access Journals (Sweden)

    Zhou Zhou

    2012-12-01

    Full Text Available Abstract Background Leptin-deficient ob/ob mice exhibit adipocyte hypertrophy and hyperplasia as well as elevated adipose tissue and systemic inflammation. Multipotent stem cells isolated from adult adipose tissue can differentiate into adipocytes ex vivo and thereby contribute toward increased adipocyte cell numbers, obesity, and inflamm ation. Currently, information is lacking regarding regulation of adipose stem cell numbers as well as leptin-induced inflammation and its signaling pathway in ob/ob mice. Methods Using leptin deficient ob/ob mice, we investigated whether leptin injection into ob/ob mice increases adipose stem cell numbers and adipose tissue inflammatory marker MCP-1 mRNA and secretion levels. We also determined leptin mediated signaling pathways in the adipose stem cells. Results We report here that adipose stem cell number is significantly increased following leptin injection in ob/ob mice and with treatment of isolated stem cells with leptin in vitro. Leptin also up-regulated MCP-1 secretion in a dose- and time-dependent manner. We further showed that increased MCP-1 mRNA levels were due to increased phosphorylation of Signal Transducer and Activator of Transcription 3 (STAT3 Ser727 but not STAT3 Tyr705 phosphorylation, suggesting differential regulation of MCP-1 gene expression under basal and leptin-stimulated conditions in adipose stem cells. Conclusions Taken together, these studies demonstrate that leptin increases adipose stem cell number and differentially activates STAT3 protein resulting in up-regulation of MCP-1 gene expression. Further studies of mechanisms mediating adipose stem cell hyperplasia and leptin signaling in obesity are warranted and may help identify novel anti-obesity target strategies.

  10. Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice

    OpenAIRE

    Sennello, Joseph A.; Fayad, Raja; Pini, Maria; Gove, Melissa E.; Fantuzzi, Giamila

    2006-01-01

    Leptin-deficient ob/ob mice exhibit several metabolic and immune abnormalities, including thymus atrophy and markedly reduced inflammatory responses. We evaluated whether transplantation of wild type (WT) white adipose tissue (WAT) into ob/ob mice could mimic the effect of recombinant leptin administration in normalizing metabolic, immune and inflammatory abnormalities. Female ob/ob mice received a subcutaneous transplantation of WAT obtained from WT littermates. A separate group of ob/ob mic...

  11. Structure and Evolution of Nearby OB Associations

    NARCIS (Netherlands)

    Brown, A. G. A.; Bruijne, J. H. J. de; Hoogerwerf, R.; Lub, J.; Le Poole, R. S.; Blaauw, A.

    1997-01-01

    Abstract: We present the first results of a comprehensive census of the stellar content of the nearby OB associations based on Hipparcos positions, proper motions and parallaxes for 12842 candidate member stars distributed over 21 fields on the sky. We use a new method to identify moving groups in t

  12. IPHAS discoveries of young stars towards Cyg OB2 and its southern periphery

    OpenAIRE

    Vink, Jorick S.; Drew, Janet E.; Steeghs, Danny; Wright, Nick J.; Martin, Eduardo L.; Gaensicke, Boris T.; Greimel, Robert; Drake, Jeremy

    2008-01-01

    We report on the discovery of over 50 strong Halpha emitting objects towards the large OB association Cyg OB2 and the HII region DR 15 on its southern periphery. This was achieved using the INT Photometric Halpha Survey of the Northern Galactic Plane (IPHAS), combined with follow-up spectroscopy using the MMT multi-object spectrometer HectoSpec. We present optical spectra, supplemented with optical r', i' and Halpha photometry from IPHAS, and near-infrared J, H, and K photometry from 2MASS. T...

  13. American Ginseng Berry Juice Intake Reduces Blood Glucose and Body Weight in ob/ob Mice

    OpenAIRE

    Xie, J.T.; Wang, C.Z.; Ni, M.; Wu, J.A.; Mehendale, S.R.; Aung, H.H.; Foo, A.; Yuan, C.S.

    2007-01-01

    Diabetes is a serious chronic metabolic disease and has a significant impact on patients' lives and the health care system. We previously observed that the organic solvent extract of American ginseng berry possessed significant antidiabetic effects in obese diabetic ob/ob mice after intraperitoneal injection. If American ginseng berry is useful as a dietary supplement, simple preparation and oral intake would be a convenient, safe, and practical means for consumers. In this study, the simply ...

  14. Adrenalectomy in genetically obese ob/ob and db/db mice increases the proton conductance pathway.

    Science.gov (United States)

    Shargill, N S; Lupien, J R; Bray, G A

    1989-09-01

    Adrenalectomy (ADX) prevents the excessive weight gain in the genetically obese ob/ob and db/db mice. To test the possibility that this results from increased energy expenditure due to increased thermogenesis in brown adipose tissue (BAT), we measured GDP binding to mitochondria from interscapular brown adipose tissue (BAT) in db/db and ob/ob mice and their lean controls after adrenalectomy, with and without corticosterone replacement. Both the vehicle treated and corticosterone treated db/db and ob/ob mice had lower body weights than the sham-operated mice GDP binding to mitochondria from IBAT was significantly lower in both the db/db and ob/ob mice than in their lean controls. Adrenalectomy significantly increased GDP binding in all mice compared to the respective sham-operated mice, but, the percentage increase was always greater in the db/db and ob/ob mice. Corticosterone treatment of adrenalectomized db/db, ob/ob or lean mice lowered GDP binding to sham levels. Our data confirm previous findings that adrenalectomy results in increased GDP binding to mitochondria from IBAT. Injections of corticosterone into adrenalectomized mice results in a decrease in GDP binding to values which are similar to values in sham-operated mice. Thus adrenalectomy may inhibit the development of obesity by increasing the thermic activity in IBAT. PMID:2583669

  15. Alleviation of ischemia/reperfusion injury in ob/ob mice by inhibiting UCP-2 expression in fatty liver

    Institute of Scientific and Technical Information of China (English)

    Chi-Dan Wan; Chun-You Wang; Tao Liu; Rui Cheng; Hong-Bo Wang

    2008-01-01

    AIM: To investigate the protective effect of target suppression of uncoupling protein-2 (UCP-2) on ischemia/ reperfusion (I/R) injury in fatty liver in ob/ob mice.METHODS: Plasmids suppressing UCP-2 expression were constructed, and transfected into fatty liver cells cultured in vitro and the ob/ob mouse I/R injury model. Serum tumor necrosis factor (TNF)-α levels, UCP-2 mRNA expression, alanine aminotransferase (ALT) levels in ob/ob mice were tested, and the pathological changes in fatty liver were observed in experimental and control groups.RESULTS: In ob/ob mouse I/R models, serum TNF-α levels were significantly higher than in normal controls. After the plasmids were transfected into the cultured cells and animal models, expression of UCP-2 mRNA was significantly reduced as compared with that in the control group (2156±015 vs 2"0-45±0-15, P < 0.05). In ob/ob mouse models, in which expression of UCP-2 was suppressed, serum ALT levels were significantly lower than those of other groups, and pathological analysis revealed that injury of liver tissues was significantly alleviated.CONCLUSION: The target suppression of UCP-2 expression in fatty liver can alleviate the I/R injury in the ob/ob mice.

  16. Time stability of ocean bottom seismometers (OBS)

    OpenAIRE

    Shariat Panahi, Shahram; Manuel Lázaro, Antonio; Corrêa Alegría, Francisco

    2010-01-01

    During the past decades, Ocean Bottom Seismometers (OBS) have played a key role in permanent seismic activity monitoring at sea as well as allowing a better understating of the earth interior. Data collected by the instrument can provide information on the ocean bottom sub-layers down to a depth of 40 km beneath the ocean floor. The accuracy of the results directly depends on the temperature stability of the crystal used as the main time base of the equipment. This paper pre...

  17. Antidiabetic effect of a novel non-thiazolidinedione PPAR γ/α agonist on ob/ob mice

    Institute of Scientific and Technical Information of China (English)

    Xi HU; Ying FENG; Yu SHEN; Xiao-feng ZHAO; Juan-hong YU; Yu-she YANG; Ying LENG

    2006-01-01

    Aim: To study whether T33, a new synthesized non-thiazolidinedione (TZD) peroxisome proliferator-activated receptor (PPAR) γ/α dual agonist has an antidiabetic effect on ob/ob mice. Methods: Ob/ob mice were treated with 4 mg/kg or 8 mg/kg T33 by gavage for 20 d. Blood glucose levels were measured regularly. An oral glucose tolerance test (OGTT) and an insulin tolerance test (ITT) were preformed on d 8 and d 12, respectively. The levels of insulin, triglyceride and free fatty acid (FFA) in the serum were measured at the end of administration. The intramuscular and liver triglyceride content was also determined. Results: T33 reduced the hyperglycemia, hyperinsulinemia and hyperlipidemia of the ob/ob mice. The OGTT and ITT showed that the insulin resistance state of the ob/ob mice was obviously ameliorated after T33 treatment. After 20 d treatment with 8 mg/kg T33, the triglyceride content in the gastrocnemius muscle decreased significantly. T33 did not have any effect on triglyceride content in the liver, whereas rosiglitazone significantly increased the hepatocyte lipid deposition. Conclusion: The PPARγ/α dual agonist T33 has antidiabetic and insulin-sensitizing effects in ob/ob mice. It has the potential to be a new therapeutic candidate for the treatment of type 2 diabetes.

  18. Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep{sup ob/ob} mice

    Energy Technology Data Exchange (ETDEWEB)

    Sekiya, Motohiro [Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655 (Japan); Yahagi, Naoya, E-mail: nyahagi-tky@umin.ac.jp [Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655 (Japan); Laboratory of Molecular Physiology on Energy Metabolism, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655 (Japan); Tamura, Yoshiaki; Okazaki, Hiroaki; Igarashi, Masaki; Ohta, Keisuke; Takanashi, Mikio; Kumagai, Masayoshi; Takase, Satoru; Nishi, Makiko; Takeuchi, Yoshinori; Izumida, Yoshihiko; Kubota, Midori; Ohashi, Ken; Iizuka, Yoko [Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655 (Japan); Yagyu, Hiroaki [Division of Endocrinology and Metabolism, Department of Medicine, Jichi Medical University, Tochigi 329-0498 (Japan); Gotoda, Takanari [Department of Nephrology and Endocrinology, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655 (Japan); Nagai, Ryozo [Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655 (Japan); Shimano, Hitoshi; Yamada, Nobuhiro [Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaragi 305-8575 (Japan); and others

    2009-09-25

    It has long been a matter of debate whether the hormone-sensitive lipase (HSL)-mediated lipolysis in pancreatic {beta}-cells can affect insulin secretion through the alteration of lipotoxicity. We generated mice lacking both leptin and HSL (Lep{sup ob/ob}/HSL{sup -/-}) and explored the role of HSL in pancreatic {beta}-cells in the setting of obesity. Lep{sup ob/ob}/HSL{sup -/-} developed elevated blood glucose levels and reduced plasma insulin levels compared with Lep{sup ob/ob}/HSL{sup +/+} in a fed state, while the deficiency of HSL did not affect glucose homeostasis in Lep{sup +/+} background. The deficiency of HSL exacerbated the accumulation of triglycerides in Lep{sup ob/ob} islets, leading to reduced glucose-stimulated insulin secretion. The deficiency of HSL also diminished the islet mass in Lep{sup ob/ob} mice due to decreased cell proliferation. In conclusion, HSL affects insulin secretary capacity especially in the setting of obesity.

  19. Preliminary results of the Source China Sea passive source OBS array experiment

    Science.gov (United States)

    Yang, T.; Liu, C.; Pei, Y.; Xia, S.

    2013-12-01

    The Scarborough, or Huangyan, Seamount chain in South China Sea (SCS) represents an extreme case of the global mid-ocean ridge system where the magmatism continues for many million years after the cessation of spreading. To understand this unique process, the South China Sea Deep (SCSD) program funded an experiment deploying a passive source OBS array to image the lithospheric structure beneath the extinct ridge. In April 2012, 18 passive source OBSs, including 15 Guralp CMG-40T OBS and 3 I-4C OBS, were deployed around the Huangyan Island for one year. 11 OBSs were successfully recovered this April, and their data are being processed. Here we present some preliminary results from analyses of this dataset, including the general quality of three-component seismograms, characteristics of seafloor ambient noise spectra, determining the OBS orientation from the Rayleigh wave polarization, and the dispersion analysis of Rayleigh waves. We found that, for most stations, seismograms from teleseismic, regional and local events are generally good with the horizontal records being comparable with vertical component. The noise levels in these seafloor stations are much higher than land-based stations, especially in shorter periods, likely suggesting the direct and stronger impact from the tempestuous SCS. Applications of more sophisticated seismic techniques such as surface wave tomography, seismic anisotropy, receiver function and ambient noise cross-correlation are underway. In addition to the low recovery rate, there are other lessons learned from this experiment. For example, at least two stations have detectable timing problems; Airgun shots should have been used to constrain the timings and orientations in both deployment and recovery. It is still challenging and costly to carry out long-term passive source seismic observations in deep sea.

  20. TNF-alpha is required for the attraction of mesenchymal precursors to white adipose tissue in Ob/ob mice.

    Directory of Open Access Journals (Sweden)

    Beatriz G Gálvez

    Full Text Available Most adult tissues harbour a stem cell subpopulation (Mesenchymal Precursors or MPs that represent a small proportion of the total cell number and have the potential to differentiate into several cell types within the mesenchymal lineage. In adipose tissue, adipocytes account for two-thirds of the total cell number. The remaining cells include blood and endothelial cells, along with adipocyte precursors (adipose MPs. Obesity is defined as an excess of body fat that frequently results in a significant impairment of health. The ob/ob mice bear a mutation in the ob gene that causes a deficiency in the hormone leptin and hence obesity. Here, we present evidence that ob/ob mice have a dramatic decrease in the resident MP pool of several tissues, including squeletal muscle, heart, lung and adipose tissue. Moreover, we show that that there is a migration of MP cells from distant organs, as well as homing of these cells to the adipose tissue mass of the ob/ob mice. We call this process adipotaxis. Once in the adipose tissue, migrant MPs undergoe adipose differentiation, giving rise to new differentiated adipocytes within the adipose mass. Finally, we provide evidence that adipotaxis is largely explained by the production of high levels of Tumor Necrosis Factor-alpha (TNF-alpha within the ob/ob adipose tissue. The therapeutic implications for human obesity as well as for regenerative medicine are further discussed in this paper.

  1. Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis

    Science.gov (United States)

    Capalbo, Luisa; Mela, Ioanna; Abad, Maria Alba; Jeyaprakash, A. Arockia; Edwardson, J. Michael

    2016-01-01

    The chromosomal passenger complex (CPC)—composed of Aurora B kinase, Borealin, Survivin and INCENP—surveys the fidelity of genome segregation throughout cell division. The CPC has been proposed to prevent polyploidy by controlling the final separation (known as abscission) of the two daughter cells via regulation of the ESCRT-III CHMP4C component. The molecular details are, however, still unclear. Using atomic force microscopy, we show that CHMP4C binds to and remodels membranes in vitro. Borealin prevents the association of CHMP4C with membranes, whereas Aurora B interferes with CHMP4C's membrane remodelling activity. Moreover, we show that CHMP4C phosphorylation is not required for its assembly into spiral filaments at the abscission site and that two distinctly localized pools of phosphorylated CHMP4C exist during cytokinesis. We also characterized the CHMP4C interactome in telophase cells and show that the centralspindlin complex associates preferentially with unphosphorylated CHMP4C in cytokinesis. Our findings indicate that gradual dephosphorylation of CHMP4C triggers a ‘relay’ mechanism between the CPC and centralspindlin that regulates the timely distribution and activation of CHMP4C for the execution of abscission. PMID:27784789

  2. Open clusters in Auriga OB2

    Science.gov (United States)

    Marco, Amparo; Negueruela, Ignacio

    2016-06-01

    We study the area around the H II region Sh 2-234, including the young open cluster Stock 8, to investigate the extent and definition of the association Aur OB2 and the possible role of triggering in massive cluster formation. We obtained Strömgren and J, H, KS photometry for Stock 8 and Strömgren photometry for two other cluster candidates in the area, which we confirm as young open clusters and name Alicante 11 and Alicante 12. We took spectroscopy of ˜33 early-type stars in the area, including the brightest cluster members. We calculate a common distance of 2.80^{+0.27}_{-0.24} kpc for the three open clusters and surrounding association. We derive an age 4-6 Ma for Stock 8, and do not find a significantly different age for the other clusters or the association. The star LS V +34°23, with spectral type O8 II(f), is likely the main source of ionization of Sh 2-234. We observe an important population of pre-main-sequence stars, some of them with discs, associated with the B-type members lying on the main sequence. We interpret the region as an area of recent star formation with some residual and very localized ongoing star formation. We do not find evidence for sequential star formation on a large scale. The classical definition of Aur OB2 has to be reconsidered, because its two main open clusters, Stock 8 and NGC 1893, are not at the same distance. Stock 8 is probably located in the Perseus arm, but other nearby H II regions whose distances also place them in this arm show quite different distances and radial velocities and, therefore, are not connected.

  3. B4C thin films for neutron detection

    OpenAIRE

    Höglund, Carina; Birch, Jens; Andersen, Ken; Bigault, Thierry; Buffet, Jean-Claude; Correa, Jonathan; Van Esch, Patrick; Guerard, Bruno; Hall-Wilton, Richard; Jensen, Jens; Khaplanov, Anton; Piscitelli, Francesco; Vettier, Christian; Vollenberg, Wilhelmus; Hultman, Lars

    2012-01-01

    Due to the very limited availability of He-3, new kinds of neutron detectors, not based on 3He, are urgently needed. Here, we present a method to produce thin films of (B4C)-B-10, with maximized detection efficiency, intended to be part of a new generation of large area neutron detectors. B4C thin Films have been deposited onto Al-blade and Si wafer substrates by dc magnetron sputtering from (B4C)-B-nat and (B4C)-B-10 targets in an Ar discharge, using an industrial deposition system. The film...

  4. Deflection routing scheme for GMPLS-based OBS networks

    DEFF Research Database (Denmark)

    Eid, Arafat; Mahmood, Waqar; Alomar, Anwar;

    2010-01-01

    Integrating the Generalized Multi-Protocol Label Switching (GMPLS) framework into an Optical Burst Switching (OBS) Control Plane is a promising solution to alleviating most of OBS performance and design issues. However, implementing the already proposed OBS deflection routing schemes is not appli......Integrating the Generalized Multi-Protocol Label Switching (GMPLS) framework into an Optical Burst Switching (OBS) Control Plane is a promising solution to alleviating most of OBS performance and design issues. However, implementing the already proposed OBS deflection routing schemes...... is not applicable in such an integrated solution. This is due to the existence of already established Label Switched Paths (LSPs) between edge nodes in a GMPLS-based OBS network which guide the Data Burst Headers (DBHs) through the network. In this paper we propose a novel deflection routing scheme which can...... be implemented in GMPLS-based OBS Control Plane. In this scheme, deflection routes or LSPs are designed and pre-established for the whole network. The ingress nodes are responsible for enabling DBHs for deflection at contending core ports prior to DBHs transmission. Moreover, we propose an object extension...

  5. Data acquisition system for a cabled ocean bottom seismometer (OBS)

    OpenAIRE

    Rogalski, Tomasz; Shariat Panahi, Shahram; Río Fernandez, Joaquín del; Manuel Lázaro, Antonio

    2010-01-01

    Ocean Bottom Seismometers (OBS) are highly used to monitor seismic activities at sea. They are also used to detect tsunamis and generate warning alarms. This paper presents a data acquisition system built for an OBS with capability to synchronize time through IEEE-1588 protocol. This acquisition system provides real time data through the Ethernet making it suitable for OBSs deployed at seafloor observatories.

  6. 4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments.

    Science.gov (United States)

    Raviram, Ramya; Rocha, Pedro P; Müller, Christian L; Miraldi, Emily R; Badri, Sana; Fu, Yi; Swanzey, Emily; Proudhon, Charlotte; Snetkova, Valentina; Bonneau, Richard; Skok, Jane A

    2016-03-01

    4C-Seq has proven to be a powerful technique to identify genome-wide interactions with a single locus of interest (or "bait") that can be important for gene regulation. However, analysis of 4C-Seq data is complicated by the many biases inherent to the technique. An important consideration when dealing with 4C-Seq data is the differences in resolution of signal across the genome that result from differences in 3D distance separation from the bait. This leads to the highest signal in the region immediately surrounding the bait and increasingly lower signals in far-cis and trans. Another important aspect of 4C-Seq experiments is the resolution, which is greatly influenced by the choice of restriction enzyme and the frequency at which it can cut the genome. Thus, it is important that a 4C-Seq analysis method is flexible enough to analyze data generated using different enzymes and to identify interactions across the entire genome. Current methods for 4C-Seq analysis only identify interactions in regions near the bait or in regions located in far-cis and trans, but no method comprehensively analyzes 4C signals of different length scales. In addition, some methods also fail in experiments where chromatin fragments are generated using frequent cutter restriction enzymes. Here, we describe 4C-ker, a Hidden-Markov Model based pipeline that identifies regions throughout the genome that interact with the 4C bait locus. In addition, we incorporate methods for the identification of differential interactions in multiple 4C-seq datasets collected from different genotypes or experimental conditions. Adaptive window sizes are used to correct for differences in signal coverage in near-bait regions, far-cis and trans chromosomes. Using several datasets, we demonstrate that 4C-ker outperforms all existing 4C-Seq pipelines in its ability to reproducibly identify interaction domains at all genomic ranges with different resolution enzymes.

  7. OB protein binds specifically to the choroid plexus of mice and rats.

    Science.gov (United States)

    Devos, R; Richards, J G; Campfield, L A; Tartaglia, L A; Guisez, Y; van der Heyden, J; Travernier, J; Plaetinck, G; Burn, P

    1996-05-28

    Binding studies were conducted to identify the anatomical location of brain target sites for OB protein, the ob gene product. 125I-labeled recombinant mouse OB protein or alkaline phosphatase-OB fusion proteins were used for in vitro and in vivo binding studies. Coronal brain sections or fresh tissue from lean, obese ob/ob, and obese db/db mice as well as lean and obese Zucker rats were probed to identify potential central OB protein-binding sites. We report here that recombinant OB protein binds specifically to the choroid plexus. The binding of OB protein (either radiolabeled or the alkaline phosphatase-OB fusion protein) and its displacement by unlabeled OB protein was similar in lean, obese ob/ob, and obese db/db mice as well as lean and obese Zucker rats. These findings suggest that OB protein binds with high affinity to a specific receptor in the choroid plexus. After binding to the choroid plexus receptor, OB protein may then be transported across the blood-brain barrier into the cerebrospinal fluid. Alternatively, binding of OB protein to a specific receptor in the choroid plexus may activate afferent neural inputs to the neural network that regulates feeding behavior and energy balance or may result in the clearance or degradation of OB protein. The identification of the choroid plexus as a brain binding site for OB protein will provide the basis for the construction of expression libraries and facilitate the rapid cloning of the choroid plexus OB receptor.

  8. Leptin Increases Striatal Dopamine D2 Receptor Binding in Leptin-Deficient Obese (ob/ob) Mice

    Energy Technology Data Exchange (ETDEWEB)

    Pfaffly, J.; Michaelides, M.; Wang, G-J.; Pessin, J.E.; Volkow, N.D.; Thanos, P.K.

    2010-06-01

    Peripheral and central leptin administration have been shown to mediate central dopamine (DA) signaling. Leptin-receptor deficient rodents show decreased DA D2 receptor (D2R) binding in striatum and unique DA profiles compared to controls. Leptin-deficient mice show increased DA activity in reward-related brain regions. The objective of this study was to examine whether basal D2R-binding differences contribute to the phenotypic behaviors of leptin-deficient ob/ob mice, and whether D2R binding is altered in response to peripheral leptin treatment in these mice. Leptin decreased body weight, food intake, and plasma insulin concentration in ob/ob mice but not in wild-type mice. Basal striatal D2R binding (measured with autoradiography [{sup 3}H] spiperone) did not differ between ob/ob and wild-type mice but the response to leptin did. In wild-type mice, leptin decreased striatal D2R binding, whereas, in ob/ob mice, leptin increased D2R binding. Our findings provide further evidence that leptin modulates D2R expression in striatum and that these effects are genotype/phenotype dependent.

  9. Strömgren and Hß photometry of O and B type stars in star-forming regions. II. Moneceros OB2, Canis Major OB1 and Collinder 121

    DEFF Research Database (Denmark)

    Kaltcheva, N.T.; Olsen, Erik Heyn; Clausen, J.V.

    1999-01-01

    Stars: Early-type - Galaxy: Open clusters and associations: Individual: Mon OB2, CMa OB1, Col 121......Stars: Early-type - Galaxy: Open clusters and associations: Individual: Mon OB2, CMa OB1, Col 121...

  10. The radial distribution of OB star formation in the Galaxy

    CERN Document Server

    Bronfman, L; May, J; Nyman, L A A

    2000-01-01

    We present the azimuthally averaged radial distribution of 748 regions of OB star formation in the whole galactic disk, based on our previous CS(2-1) survey of UC H II regions. Embedded massive stars produce a total FIR luminosity of 1.39E8 Lsun within the range 0.2

  11. Retention of deuterium implanted into B4C-overlaid isotropic graphites and hot-pressed B4C

    International Nuclear Information System (INIS)

    Retention characteristics of two kinds of B4C-overlaid graphites and hot-pressed B4C were investigated. An ion beam of 3 keV D2+ was implanted into the specimens at room temperature. The amount of retained deuteriums was measured as function of the implantation fluence and temperature by elastic recoil detection analysis. Thermal release behavior of implanted deuteriums was also measured by isochronal annealing. The concentration of retained deuterium reaches saturation similarly in three kinds of B4C-overlaid specimens at the fluences over 1018 D+/cm2 as in isotropic graphite. The release temperature, at which the number of retained deuterium decreases to one half in isochronal annealing are about 250 K lower for three kinds of B4C specimens than for graphite. The release temperature of deuterium from unsaturated hot-pressed B4C isochronal annealing is about 500 K higher than that from saturated one. (orig.)

  12. Spatial Distribution and Kinematics of OB Stars

    CERN Document Server

    Gontcharov, George

    2016-01-01

    The sample of 37 485 suspected OB stars selected by Gontcharov (2008) from the Tycho-2 catalogue has been cleaned of the stars that are not of spectral types OV--A0V. For this purpose, the apparent magnitude $V_T$ from Tycho-2, the absolute magnitude $M_{V_T}$ calibrated as a function of the dereddened color index $(B_T-V_T)_0$, the interstellar extinction $A_{V_T}$ calculated from the 3D analytical model by Gontcharov (2009) as a function of the Galactic coordinates, and the photometric distance $r_{ph}$ calculated as a function of $V_T$, $M_{V_T}$, and $A_{V_T}$ have been reconciled in an iterative process. The 20 514 stars that passed the iterations have $(B_T-V_T)_0-5$ and are considered as a sample of OV--A0V stars complete within 350 pc of the Sun. Based on the theoretical relation between the dereddened color and age of the stars, the derived sample has been divided into three subsamples: $(B_T-V_T)_0<-0.2^m$, $-0.2^m<(B_T-V_T)_0<-0.1^m$, and $-0.1^m<(B_T-V_T)_0<0^m$, younger than 100, $...

  13. Open clusters in AurOB2

    CERN Document Server

    Marco, A

    2016-01-01

    We study the area around the HII region Sh 2-234, including the young open cluster Stock 8, to investigate the extent and definition of the association Aur OB2 and the possible role of triggering in massive cluster formation. We obtained Str\\"omgren and J,H,Ks photometry for Stock 8 and Str\\"omgren photometry for two other cluster candidates in the area, which we confirm as young open clusters and name Alicante 11 and Alicante 12. We took spectroscopy of 33 early-type stars in the area, including the brightest cluster members. We calculate a common distance of $2.80^{+0.27}_{-0.24}$ kpc for the three open clusters and surrounding association. We derive an age 4-6 Ma for Stock 8, and do not find a significantly different age for the other clusters or the association. The star LSV +34 23, with spectral type O8 II(f), is likely the main source of ionization of Sh 2-234. We observe an important population of pre-main sequence stars, some of them with disks, associated with the B-type members lying on the main-seq...

  14. Reverse time migration of multiples for OBS data

    KAUST Repository

    Zhang, Dongliang

    2014-08-05

    Reverse time migration of multiples (RTMM) is applied to OBS data with sparse receiver spacing. RTMM for OBS data unlike a marine streamer acquisition is implemented in the common receiver gathers (CRG) and provides a wider and denser illumination for each CRG than the conventional RTM of primaries. Hence, while the the conventional RTM image contains strong aliasing artifacts due to a sparser receiver interval, the RTMM image suffers from this artifacts less. This benefit of RTMM is demonstrated with numerical test on the Marmousi model for sparsely sampled OBS data.

  15. ESTIMATION OF THE BURST LENGTH IN OBS NETWORKS

    OpenAIRE

    Pallavi S.; M. Lakshmi

    2014-01-01

    This paper presents an overview of the optical burst switching (OBS) and discusses the major components. In OBS, the length of the burst arriving at a particular node is unknown, and hence, node design is very complex. In OBS first control, packet is transmitted and reserve the path as in circuit switching, thereafter, the data bursts is transmitted. In this paper, a poisson arrival of packets is considered and estimation is made on the size of the burst length. The results presented in the p...

  16. Performance of a distributed WR-OBS control architecture

    Institute of Scientific and Technical Information of China (English)

    Zhou Lan; Hongxiang Guo; Jian Wu; Jintong Lin

    2005-01-01

    This paper proposes a new distributed wavelength-routed optical burst switching (WR-OBS) network architecture and two corresponding control protocols. By taking advantage of merits from both just enough time (JET) protocol and two-way signaling method, this new control architecture outperforms traditional JET OBS network in points of burst loss probability, system throughput and centralized WROBS network in network scalability confirmed by computer simulations. Further simulation is developed to compare the performance of the two control protocols, which leads to instructive discussion in real WR-OBS network design.

  17. Nonlinear waveform analysis for water-layer response and its application to high-frequency receiver function analysis using OBS array

    Science.gov (United States)

    Akuhara, Takeshi; Mochizuki, Kimihiro; Kawakatsu, Hitoshi; Takeuchi, Nozomu

    2016-07-01

    Determination of a response of the seawater column to teleseismic plane wave is important to suppress adverse effects of water reverberations in calculating receiver functions (RFs) using ocean-bottom seismometer (OBS) records. We present a novel nonlinear-waveform analysis method using the simulated annealing algorithm to determine such a water-layer response recorded by an OBS array. We then demonstrate its usefulness for the RF estimation through its application to synthetic and observed data. Synthetic experiments suggest that the water-layer response constrained in this way has a potential to improve RFs of OBS records drastically even in the high-frequency range (to 4 Hz). By applying it to data observed by the OBS array around the Kii Peninsula, southwestern Japan, we identified a low-velocity zone at the top of the subducting Philippine Sea plate. This zone may represent the incoming fluid-rich sediment layer that has been reported by active source seismic survey.

  18. A M2FS Spectroscopic Study of Low-mass Young Stars in Orion OB1

    Science.gov (United States)

    Kaleida, Catherine C.; Briceno, Cesar; Calvet, Nuria; Mateo, Mario L.; Hernandez, Jesus

    2015-01-01

    Surveys of pre-main sequence stars in the ~4-10 Myr range provide a window into the decline of the accretion phase of stars and the formation of planets. Nearby star clusters and stellar associations allow for the study of these young stellar populations all the way down to the lowest mass members. One of the best examples of nearby 4-10 Myr old stellar populations is the Orion OB1 association. The CIDA Variability Survey of Orion OB1 (CVSO - Briceño et al. 2001) has used the variability properties of low-mass pre-main-sequence (PMS) stars to identify hundreds of K and M-type stellar members of the Orion OB1 association, a number of them displaying IR-excess emission and thought to be representative of more evolved disk-bearing young stars. Characterizing these young, low-mass objects using spectroscopy is integral to understanding the accretion phase in young stars. We present preliminary results of a spectroscopic survey of candidate and confirmed Orion OB1 low-mass members taken during November 2014 and February 2014 using the Michigan/Magellan Fiber Spectrograph (M2FS), a PI instrument on the Magellan Clay Telescope (PI: M. Matteo). Target fields located in the off-cloud regions of Orion were identified in the CVSO, and observed using the low and high-resolution modes of M2FS. Both low and high-resolution spectra are needed in order to confirm membership and derive masses, ages, kinematics and accretion properties. Initial analysis of these spectra reveal many new K and M-type members of the Orion OB1 association in these low extinction, off-cloud areas. These are the more evolved siblings of the youngest stars still embedded in the molecular clouds, like those in the Orion Nebula Cluster. With membership and spectroscopic indicators of accretion we are building the most comprehensive stellar census of this association, enabling us to derive a robust estimate of the fraction of young stars still accreting at a various ages, a key constraint for the end of

  19. Boron carbide (B4C) coating. Deposition and testing

    Science.gov (United States)

    Azizov, E.; Barsuk, V.; Begrambekov, L.; Buzhinsky, O.; Evsin, A.; Gordeev, A.; Grunin, A.; Klimov, N.; Kurnaev, V.; Mazul, I.; Otroshchenko, V.; Putric, A.; Sadovskiy, Ya.; Shigin, P.; Vergazov, S.; Zakharov, A.

    2015-08-01

    Boron carbide was proposed as a material of in-situ protecting coating for tungsten tiles of ITER divertor. To prove this concept the project including investigation of regimes of plasma deposition of B4C coating on tungsten and tests of boron carbide layer in ITER-like is started recently. The paper contends the first results of the project. The results of B4C coating irradiation by the plasma pulses of QSPU-T plasma accelerator are presented. The new device capable of B4C film deposition on tungsten and testing of the films and materials with ITER-like heat loads and ion- and electron irradiation is described. The results of B4C coating deposition and testing of both tungsten substrate and coating are shown and discussed.

  20. IPHAS discoveries of young stars towards Cyg OB2 and its southern periphery

    CERN Document Server

    Vink, Jorick S; Steeghs, Danny; Wright, Nick J; Martin, Eduardo L; Gaensicke, Boris T; Greimel, Robert; Drake, Jeremy

    2008-01-01

    We report on the discovery of over 50 strong Halpha emitting objects towards the large OB association Cyg OB2 and the HII region DR 15 on its southern periphery. This was achieved using the INT Photometric Halpha Survey of the Northern Galactic Plane (IPHAS), combined with follow-up spectroscopy using the MMT multi-object spectrometer HectoSpec. We present optical spectra, supplemented with optical r', i' and Halpha photometry from IPHAS, and near-infrared J, H, and K photometry from 2MASS. The position of the objects in the (J - H) versus (H - K) diagram strongly suggests most of them are young. Many show CaII IR triplet emission indicating that they are in a pre-main sequence phase of evolution of T Tauri and Herbig Ae nature. Among these, we have uncovered pronounced clustering of T Tauri stars roughly a degree south of the centre of Cyg OB2, in an arc close to the HII region DR 15, and the radio ring nebula G79.29+0.46, for which we discuss its candidacy as a luminous blue variable (LBV). The emission lin...

  1. Variability monitoring of OB stars during the Mons campaign

    CERN Document Server

    Morel, T; Eversberg, T; Alves, F; Arnold, W; Bergmann, T; Viegas, N G Correia; Fahed, R; Fernando, A; Carreira, L F Gouveia; Hunger, T; Knapen, J H; Leadbeater, R; Dias, F Marques; Moffat, A F J; Reinecke, N; Ribeiro, J; Romeo, N; Gallego, J Sanchez; Santos, E M dos; Schanne, L; Stahl, O; Stober, Ba; Stober, Be; Vollmann, K; Corcoran, M F; Dougherty, S M; Hamaguchi, K; Pittard, J M; Pollock, A M T; Williams, P M

    2010-01-01

    We present preliminary results of a 3-month campaign carried out in the framework of the Mons project, where time-resolved Halpha observations are used to study the wind and circumstellar properties of a number of OB stars.

  2. Analysis of methane biodegradation by Methylosinus trichosporium OB3b

    OpenAIRE

    Rodrigues, Andréa dos Santos; Salgado, Belkis Valdman e Andréa Medeiros

    2009-01-01

    The microbial oxidation of methane in the atmosphere is performed by methanotrophic bacteria that use methane as a unique source of carbon and energy. The objective of this work consisted of the investigation of the best conditions of methane biodegradation by methanotrophic bacteria Methylosinus trichosporium OB3b that oxidize it to carbon dioxide, and the use of these microorganisms in monitoring methods for methane. The results showed that M. trichosporium OB3b was capable to degrade metha...

  3. Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice.

    Science.gov (United States)

    Xue, Han; Chen, Di; Zhong, Yan-Ke; Zhou, Zhen-Diao; Fang, Shi-Xin; Li, Ming-Yao; Guo, Chuang

    2016-07-01

    Hepatic iron accumulation may be responsible for the pathology of nonalcoholic fatty liver disease (NAFLD), which is both increasingly prevalent in conjunction with obesity and associated with comorbidities. The efficacy of iron reduction therapies, such as phlebotomy or dietary iron restriction, has been demonstrated in patient and animal models, including models of diabetes and obesity; however, the effects on and exact mechanisms responsible for iron depletion in NAFLD have not been clearly elucidated. Our study investigated the role of iron depletion by deferoxamine (DFO) treatment of ob/ob mice with hepatic steatosis. We found that DFO reduced hepatic iron deposition and regulated intracellular iron concentration in a homeostatic process following 15 days of treatment. Compared with vehicle treatment, DFO significantly improved hepatic steatosis by upregulating proteins related to lipid metabolism. Meanwhile, the reduction of free radical formation and proinflammatory cytokines, as well as the increase of hypoxia-inducible factor-1α pathway proteins and Bcl2/Bax ratio, further indicated that DFO was effective for liver protection and hepatic adaptation. These findings show that the intraperitoneal delivery of DFO provides a potential means of both preventing the progression of NAFLD and accelerating healing of hepatic steatosis, with the potential for rapid clinical application. PMID:27447538

  4. Impaired transport of thyroid hormones into livers of obese (ob/ob) mice

    International Nuclear Information System (INIS)

    Obese (ob/ob) mice exhibit impaired hepatic thyroid hormone action that is mediated, at least in part, by a reduced nuclear 3,5,3'-triiodothyronine (T3) receptor occupancy. The possibility that lowered occupancy in obese mice may be caused by decreased transport of T3 across the hepatic plasma membrane was examined by measuring the unidirectional influx of [125I]T3 into livers of 8- to 10-wk-old obese and lean mice using a tissue-sampling portal vein-injection technique. Influx of [125I]thyroxine (T4), a substrate for T4 5'-deiodinase, was also measured. Unidirectional clearance of T3 and T4 was 64 and 80% lower, respectively, in obese mice than in lean mice. Hepatic T3 and T4 uptake was nonsaturable in both lean and obese mice, suggesting that transport occurs by lipid-mediated free diffusion. Clearance of another lipid-soluble hormone, hydrocortisone, was also lower in obese mice than in lean mice. Decreased membrane permeability to the above hormones in obese mice may result from reported changes in membrane lipid composition. In conclusion, decreased hepatic thyroid hormone uptake may contribute to impaired thyroid hormone action and T3 production in livers of obese mice

  5. Cygnus OB2 DANCe: A high precision proper motion study of the Cygnus OB2 association

    CERN Document Server

    Wright, Nicholas J; Drew, Janet E; Sarro, Luis Manuel; Bertin, Emmanuel; Cuillandre, Jean-Charles; Barrado, David

    2016-01-01

    We present a high-precision proper motion study of 873 X-ray and spectroscopically selected stars in the massive OB association Cygnus OB2 as part of the DANCe project. These were calculated from images spanning a 15 year baseline and have typical precisions < 1 mas/yr. We calculate the velocity dispersion in the two axes to be $\\sigma_\\alpha(c) = 13.0^{+0.8}_{-0.7}$ and $\\sigma_\\delta(c) = 9.1^{+0.5}_{-0.5}$ km/s, using a 2-component, 2-dimensional model that takes into account the uncertainties on the measurements. This gives a 3-dimensional velocity dispersion of $\\sigma_{3D} = 17.8 \\pm 0.6$ km/s implying a virial mass significantly larger than the observed stellar mass, confirming that the association is gravitationally unbound. The association appears to be dynamically unevolved, as evidenced by considerable kinematic substructure, non-isotropic velocity dispersions and a lack of energy equipartition. The proper motions show no evidence for a global expansion pattern, with approximately the same amoun...

  6. Brown Adipose Tissue Transplantation Reverses Obesity in Ob/Ob Mice.

    Science.gov (United States)

    Liu, Xiaomeng; Wang, Siping; You, Yilin; Meng, Minghui; Zheng, Zongji; Dong, Meng; Lin, Jun; Zhao, Qianwei; Zhang, Chuanhai; Yuan, Xiaoxue; Hu, Tao; Liu, Lieqin; Huang, Yuanyuan; Zhang, Lei; Wang, Dehua; Zhan, Jicheng; Jong Lee, Hyuek; Speakman, John R; Jin, Wanzhu

    2015-07-01

    Increasing evidence indicates that brown adipose tissue (BAT) transplantation enhances whole-body energy metabolism in a mouse model of diet-induced obesity. However, it remains unclear whether BAT also has such beneficial effects on genetically obese mice. To address this issue, we transplanted BAT from C57/BL6 mice into the dorsal subcutaneous region of age- and sex-matched leptin deficient Ob/Ob mice. Interestingly, BAT transplantation led to a significant reduction of body weight gain with increased oxygen consumption and decreased total body fat mass, resulting in improvement of insulin resistance and liver steatosis. In addition, BAT transplantation increased the level of circulating adiponectin, whereas it reduced the levels of circulating free T3 and T4, which regulate thyroid hormone sensitivity in peripheral tissues. BAT transplantation also increased β3-adrenergic receptor and fatty acid oxidation related gene expression in subcutaneous and epididymal (EP) white adipose tissue. Accordingly, BAT transplantation increased whole-body thermogenesis. Taken together our results demonstrate that BAT transplantation may reduce obesity and its related diseases by activating endogenous BAT.

  7. Signals embedded in the OBS records, in light of Gabor Spectral Analysis

    Science.gov (United States)

    Chang, T.; Wang, Y.; Chang, C.; Lee, C.

    2005-12-01

    Since the last decades, seismological survey has been expanded to marine area, with goal of making up the deficiency of seismogenic study outside the land. Although teleseismic data can resolve plate boundaries location and certain seismic parameters for great earthquake, local seismogenic frame can be merely emerged by the seismic network in situ. The Ocean Bottom Seismometer (OBS), therefore, is developing for this kind of purpose and becoming an important facility for seismological study. This work introduces a synthesized spectral method to analyze the seismograms recorded by 15 OBS deployed at the Okinawa trough in 14 days (Nov. 19 ~Dec. 2, 2003). Geological background of Okinawa trough is well known to correspond with the back-arc spreading in the regime of the Philippine Sea plate subducting northward beneath the Eurasia plate. As the complex affections at sea bottom, for instance, strong current, slope slumping, turbidite flow, and even sea animal attack, the OBS seismogram show a rather noisy sequence in comparison with the record on land. However, hundreds of tectonic earthquake can be extracted from such noisy records (done by Drs. Lin and Sibuet). Our job is to sort out the signals with the distinguishable sources by means of a systematically spectral analysis. The continuous wavelet transform and short-term Fourier transform, both taking Gaussian function as kernel, are synthesized as the Gabor transform in data process. The use of a limited Gaussian window along time axis with negligible low frequency error can largely enhance the stability of discrete Fourier spectrum. With a proper window factor selection, the Gabor transform can improve the resolution of spectrogram in time domain. We have converted the OBS records into spectrograms to detect the variation of signal causes. Up-to-date, some tremors signals and strong current oscillations have been told apart from these continuous records with varied frequency composing. We anticipate the further

  8. Preliminary performance report of the RHUM-RUM OBS network

    Science.gov (United States)

    Stähler, Simon C.; Crawford, Wayne; Barruol, Guilhem; Sigloch, Karin; Mechita, Schmidt-Aursch

    2015-04-01

    RHUM-RUM is a German-French seismological experiment based on the seafloor surrounding the hotspot of La Réunion, western Indian Ocean. Its primary objective is to clarify the presence or absence of a mantle plume beneath the Reunion hotspot. RHUM-RUM's central component is a one-year deployment (Oct 2012 - Nov 2013) of 57 broadband ocean-bottom seismometers (OBS) and hydrophones on an area of 2000x2000 km2 surrounding the hotspot. The OBS pool contained 48 instruments from the German DEPAS pool and 9 French stations from INSU. All OBS have been successfully recovered. Preliminary analysis of the seismometer recordings show large differences in long-period (>10s) noise levels between the German and the French OBS. These differences are strongest on the horizontal components and can be probably explained by dynamic tilt of the instrument itself. The noise level of the German instruments is >20dB higher in this period range compared to the French ones. A reason could be that for the German OBS, the seismometer is integrated into the OBS frame and therefore affected by its movement due to currents. The high noise level on the horizontal components will have to be considered in future experiment design, when using this instrument type for three-component waveform tomography.

  9. Gender-specific metabolomic profiling of obesity in leptin-deficient ob/ob mice by 1H NMR spectroscopy.

    Directory of Open Access Journals (Sweden)

    Eun-Young Won

    Full Text Available Despite the numerous metabolic studies on obesity, gender bias in obesity has rarely been investigated. Here, we report the metabolomic analysis of obesity by using leptin-deficient ob/ob mice based on the gender. Metabolomic analyses of urine and serum from ob/ob mice compared with those from C57BL/6J lean mice, based on the (1H NMR spectroscopy in combination with multivariate statistical analysis, revealed clear metabolic differences between obese and lean mice. We also identified 48 urine and 22 serum metabolites that were statistically significantly altered in obese mice compared to lean controls. These metabolites are involved in amino acid metabolism (leucine, alanine, ariginine, lysine, and methionine, tricarbocylic acid cycle and glucose metabolism (pyruvate, citrate, glycolate, acetoacetate, and acetone, lipid metabolism (cholesterol and carnitine, creatine metabolism (creatine and creatinine, and gut-microbiome-derived metabolism (choline, TMAO, hippurate, p-cresol, isobutyrate, 2-hydroxyisobutyrate, methylamine, and trigonelline. Notably, our metabolomic studies showed distinct gender variations. The obese male mice metabolism was specifically associated with insulin signaling, whereas the obese female mice metabolism was associated with lipid metabolism. Taken together, our study identifies the biomarker signature for obesity in ob/ob mice and provides biochemical insights into the metabolic alteration in obesity based on gender.

  10. Calorimetric measurements on Li{sub 4}C{sub 60} and Na{sub 4}C{sub 60}

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, Akira; Miyazaki, Yuji [Research Center for Structural Thermodynamics, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043 (Japan); Michałowski, Paweł P.; Gracia-Espino, Eduardo; Wågberg, Thomas, E-mail: Thomas.wagberg@physics.umu.se [Department of Physics, Umeå University, S-90187 Umeå (Sweden); Sundqvist, Bertil [Department of Physics, Umeå University, S-90187 Umeå (Sweden); State Key Laboratory for Superhard Materials, Jilin University, Changchun 130012 (China)

    2015-04-28

    We show specific heat data for Na{sub 4}C{sub 60} and Li{sub 4}C{sub 60} in the range 0.4-350 K for samples characterized by Raman spectroscopy and X-ray diffraction. At high temperatures, the two different polymer structures have very similar specific heats both in absolute values and in general trend. The specific heat data are compared with data for undoped polymeric and pristine C{sub 60}. At high temperatures, a difference in specific heat between the intercalated and undoped C{sub 60} polymers of 100 J K{sup −1} mol{sup −1} is observed, in agreement with the Dulong-Petit law. At low temperatures, the specific heat data for Li{sub 4}C{sub 60} and Na{sub 4}C{sub 60} are modified by the stiffening of vibrational and librational molecular motion induced by the polymer bonds. The covalent twin bonds in Li{sub 4}C{sub 60} affect these motions to a somewhat higher degree than the single intermolecular bonds in Na{sub 4}C{sub 60}. Below 1 K, the specific heats of both materials become linear in temperature, as expected from the effective dimensionality of the structure. The contribution to the total specific heat from the inserted metal ions can be well described by Einstein functions with T{sub E} = 386 K for Li{sub 4}C{sub 60} and T{sub E} = 120 K for Na{sub 4}C{sub 60}, but for both materials we also observe a Schottky-type contribution corresponding to a first approximation to a two-level system with ΔE = 9.3 meV for Li{sub 4}C{sub 60} and 3.1 meV for Na{sub 4}C{sub 60}, probably associated with jumps between closely spaced energy levels inside “octahedral-type” ionic sites. Static magnetic fields up to 9 T had very small effects on the specific heat below 10 K.

  11. B4C thin films for neutron detection

    International Nuclear Information System (INIS)

    Due to the very limited availability of 3He, new kinds of neutron detectors, not based on 3He, are urgently needed. Here, we present a method to produce thin films of 10B4C, with maximized detection efficiency, intended to be part of a new generation of large area neutron detectors. B4C thin films have been deposited onto Al-blade and Si wafer substrates by dc magnetron sputtering from natB4C and 10B4C targets in an Ar discharge, using an industrial deposition system. The films were characterized with scanning electron microscopy, elastic recoil detection analysis, x-ray reflectivity, and neutron radiography. We show that the film-substrate adhesion and film purity are improved by increased substrate temperature and deposition rate. A deposition rate of 3.8 A/s and substrate temperature of 400 deg. C result in films with a density close to bulk values and good adhesion to film thickness above 3 μm. Boron-10 contents of almost 80 at. % are obtained in 6.3 m2 of 1 μm thick 10B4C thin films coated on Al-blades. Initial neutron absorption measurements agree with Monte Carlo simulations and show that the layer thickness, number of layers, neutron wavelength, and amount of impurities are determining factors. The study also shows the importance of having uniform layer thicknesses over large areas, which for a full-scale detector could be in total ∼1000 m2 of two-side coated Al-blades with ∼1 μm thick 10B4C films.

  12. B{sub 4}C thin films for neutron detection

    Energy Technology Data Exchange (ETDEWEB)

    Hoeglund, Carina [European Spallation Source ESS AB, P.O. Box 176, SE-221 00 Lund (Sweden); Department of Physics, Chemistry and Biology (IFM), Thin Film Physics Division, Linkoeping University, SE-581 83 Linkoeping (Sweden); Birch, Jens; Jensen, Jens; Hultman, Lars [Department of Physics, Chemistry and Biology (IFM), Thin Film Physics Division, Linkoeping University, SE-581 83 Linkoeping (Sweden); Andersen, Ken; Hall-Wilton, Richard [European Spallation Source ESS AB, P.O. Box 176, SE-221 00 Lund (Sweden); Bigault, Thierry; Buffet, Jean-Claude; Correa, Jonathan; Esch, Patrick van; Guerard, Bruno; Piscitelli, Francesco [Institute Laue Langevin, Rue Jules Horowitz, FR-380 00 Grenoble (France); Khaplanov, Anton [European Spallation Source ESS AB, P.O. Box 176, SE-221 00 Lund (Sweden); Institute Laue Langevin, Rue Jules Horowitz, FR-380 00 Grenoble (France); Vettier, Christian [European Spallation Source ESS AB, P.O. Box 176, SE-221 00 Lund (Sweden); European Synchrotron Radiation Facility, BP 220, FR-380 43 Grenoble Cedex 9 (France); Vollenberg, Wilhelmus [Vacuum, Surfaces and Coatings Group (TE/VSC), CERN, CH-1211 Geneva 23 (Switzerland)

    2012-05-15

    Due to the very limited availability of {sup 3}He, new kinds of neutron detectors, not based on {sup 3}He, are urgently needed. Here, we present a method to produce thin films of {sup 10}B{sub 4}C, with maximized detection efficiency, intended to be part of a new generation of large area neutron detectors. B{sub 4}C thin films have been deposited onto Al-blade and Si wafer substrates by dc magnetron sputtering from {sup nat}B{sub 4}C and {sup 10}B{sub 4}C targets in an Ar discharge, using an industrial deposition system. The films were characterized with scanning electron microscopy, elastic recoil detection analysis, x-ray reflectivity, and neutron radiography. We show that the film-substrate adhesion and film purity are improved by increased substrate temperature and deposition rate. A deposition rate of 3.8 A/s and substrate temperature of 400 deg. C result in films with a density close to bulk values and good adhesion to film thickness above 3 {mu}m. Boron-10 contents of almost 80 at. % are obtained in 6.3 m{sup 2} of 1 {mu}m thick {sup 10}B{sub 4}C thin films coated on Al-blades. Initial neutron absorption measurements agree with Monte Carlo simulations and show that the layer thickness, number of layers, neutron wavelength, and amount of impurities are determining factors. The study also shows the importance of having uniform layer thicknesses over large areas, which for a full-scale detector could be in total {approx}1000 m{sup 2} of two-side coated Al-blades with {approx}1 {mu}m thick {sup 10}B{sub 4}C films.

  13. Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets

    Science.gov (United States)

    Lindenmaier, Laurence B.; Philbrick, Kenneth A.; Branscum, Adam J.; Kalra, Satya P.; Turner, Russell T.; Iwaniec, Urszula T.

    2016-01-01

    Low bone mass is often associated with elevated bone marrow adiposity. Since osteoblasts and adipocytes are derived from the same mesenchymal stem cell (MSC) progenitor, adipocyte formation may increase at the expense of osteoblast formation. Leptin is an adipocyte-derived hormone known to regulate energy and bone metabolism. Leptin deficiency and high-fat diet-induced obesity are associated with increased marrow adipose tissue (MAT) and reduced bone formation. Short-duration studies suggest that leptin treatment reduces MAT and increases bone formation in leptin-deficient ob/ob mice fed a regular diet. Here, we determined the long-duration impact of increased hypothalamic leptin on marrow adipocytes and osteoblasts in ob/ob mice following recombinant adeno-associated virus (rAAV) gene therapy. Eight- to 10-week-old male ob/ob mice were randomized into four groups: (1) untreated, (2) rAAV-Lep, (3) rAAV-green fluorescent protein (rAAV-GFP), or (4) pair-fed to rAAV-Lep. For vector administration, mice were injected intracerebroventricularly with either rAAV-leptin gene therapy (rAAV-Lep) or rAAV-GFP (9 × 107 particles) and maintained for 30 weeks. In a second study, the impact of increased hypothalamic leptin levels on MAT was determined in mice fed high-fat diets; ob/ob mice were randomized into two groups and treated with either rAAV-Lep or rAAV-GFP. At 7 weeks post-vector administration, half the mice in each group were switched to a high-fat diet for 8 weeks. Wild-type (WT) controls included age-matched mice fed regular or high-fat diet. High-fat diet resulted in a threefold increase in MAT in WT mice, whereas MAT was increased by leptin deficiency up to 50-fold. Hypothalamic leptin gene therapy increased osteoblast perimeter and osteoclast perimeter with minor change in cancellous bone architecture. The gene therapy decreased MAT levels in ob/ob mice fed regular or high-fat diet to values similar to WT mice fed regular diet. These findings suggest

  14. Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets.

    Science.gov (United States)

    Lindenmaier, Laurence B; Philbrick, Kenneth A; Branscum, Adam J; Kalra, Satya P; Turner, Russell T; Iwaniec, Urszula T

    2016-01-01

    Low bone mass is often associated with elevated bone marrow adiposity. Since osteoblasts and adipocytes are derived from the same mesenchymal stem cell (MSC) progenitor, adipocyte formation may increase at the expense of osteoblast formation. Leptin is an adipocyte-derived hormone known to regulate energy and bone metabolism. Leptin deficiency and high-fat diet-induced obesity are associated with increased marrow adipose tissue (MAT) and reduced bone formation. Short-duration studies suggest that leptin treatment reduces MAT and increases bone formation in leptin-deficient ob/ob mice fed a regular diet. Here, we determined the long-duration impact of increased hypothalamic leptin on marrow adipocytes and osteoblasts in ob/ob mice following recombinant adeno-associated virus (rAAV) gene therapy. Eight- to 10-week-old male ob/ob mice were randomized into four groups: (1) untreated, (2) rAAV-Lep, (3) rAAV-green fluorescent protein (rAAV-GFP), or (4) pair-fed to rAAV-Lep. For vector administration, mice were injected intracerebroventricularly with either rAAV-leptin gene therapy (rAAV-Lep) or rAAV-GFP (9 × 10(7) particles) and maintained for 30 weeks. In a second study, the impact of increased hypothalamic leptin levels on MAT was determined in mice fed high-fat diets; ob/ob mice were randomized into two groups and treated with either rAAV-Lep or rAAV-GFP. At 7 weeks post-vector administration, half the mice in each group were switched to a high-fat diet for 8 weeks. Wild-type (WT) controls included age-matched mice fed regular or high-fat diet. High-fat diet resulted in a threefold increase in MAT in WT mice, whereas MAT was increased by leptin deficiency up to 50-fold. Hypothalamic leptin gene therapy increased osteoblast perimeter and osteoclast perimeter with minor change in cancellous bone architecture. The gene therapy decreased MAT levels in ob/ob mice fed regular or high-fat diet to values similar to WT mice fed regular diet. These findings suggest

  15. LiFePO_4/C via fluoride doping

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Non-stoichiometric compound fluoride-doped LiFePO4/C cathode materials were synthesized via solid-state reaction using MgF2 and AlF3 as dopant. The fluoride-doped LiFePO4/C samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and electrochemical testing. The results show that the materials are well crystallized and fluoride doping cannot change the space structure of LiFePO4. Slight amounts of Fe2O3 with no fluoride impurity were ...

  16. Wind collisions in three massive stars of Cyg OB2

    CERN Document Server

    Cazorla, Constantin; Rauw, Gregor

    2013-01-01

    Aims: We wish to study the origin of the X-ray emission of three massive stars in the Cyg OB2 association: Cyg OB2 #5, #8A, #12. Methods: To this aim, dedicated X-ray observations from XMM and Swift are used, as well as archival ROSAT and Suzaku data. Results: Our results on Cyg OB2 #8A improve the phase coverage of the orbit and confirm previous studies: the signature of a wind-wind collision is conspicuous. In addition, signatures of a wind-wind collision are also detected in Cyg OB2 #5, but the X-ray emission appears to be associated with the collision between the inner binary and the tertiary component orbiting it with a 6.7yr period, without a putative collision inside the binary. The X-ray properties strongly constrain the orbital parameters, notably allowing us to discard some proposed orbital solutions. To improve the knowledge of the orbit, we revisit the light curves and radial velocity of the inner binary, looking for reflex motion induced by the third star. Finally, the X-ray emission of Cyg OB2 #...

  17. Herbig Ae/Be Stars in nearby OB associations

    CERN Document Server

    Hernández, J; Hartmann, L; Briceño, C; Sicilia-Aguilar, A; Berlind, P; Hernandez, Jesus; Calvet, Nuria; Hartmann, Lee; Briceno, Cesar; Sicilia-Aguilar, Aurora; Berlind, Perry

    2004-01-01

    We have carried out a study of the early type stars in nearby OB associations spanning an age range of $\\sim$ 3 to 16 Myr, with the aim of determining the fraction of stars which belong to the Herbig Ae/Be class. We studied the B, A, and F stars in the nearby ($\\le 500$ pc) OB associations Upper Scorpius, Perseus OB2, Lacerta OB1, and Orion OB1, with membership determined from Hipparcos data. We obtained spectra for 440 Hipparcos stars in these associations, from which we determined accurate spectral types, visual extinctions, effective temperatures, luminosities and masses, using Hipparcos photometry. Using colors corrected for reddening, we find that the Herbig Ae/Be stars and the Classical Be stars (CBe) occupy clearly different regions in the JHK diagram. Thus, we use the location on the JHK diagram, as well as the presence of emission lines and of strong 12 microns flux relative to the visual to identify the Herbig Ae/Be stars in the associations. We find that the Herbig Ae/Be stars constitute a small fr...

  18. Increasing the number and signal-to-noise ratio of OBS traces with supervirtual refraction interferometry and free-surface multiples

    KAUST Repository

    Bharadwaj, P.

    2013-01-10

    The theory of supervirtual interferometry is modified so that free-surface related multiple refractions can be used to enhance the signal-to-noise ratio (SNR) of primary refraction events by a factor proportional to√Ns, where Ns is the number of post-critical sources for a specified refraction multiple. We also show that refraction multiples can be transformed into primary refraction events recorded at virtual hydrophones located between the actual hydrophones. Thus, data recorded by a coarse sampling of ocean bottom seismic (OBS) stations can be transformed, in principle, into a virtual survey with P times more OBS stations, where P is the order of the visible free-surface related multiple refractions. The key assumption is that the refraction arrivals are those of head waves, not pure diving waves. The effectiveness of this method is validated with both synthetic OBS data and an OBS data set recorded offshore from Taiwan. Results show the successful reconstruction of far-offset traces out to a source-receiver offset of 120 km. The primary supervirtual traces increase the number of pickable first arrivals from approximately 1600 to more than 3100 for a subset of the OBS data set where the source is only on one side of the recording stations. In addition, the head waves associated with the first-order free-surface refraction multiples allow for the creation of six new common receiver gathers recorded at virtual OBS station located about half way between the actual OBS stations. This doubles the number of OBS stations compared to the original survey and increases the total number of pickable traces from approximately 1600 to more than 6200. In summary, our results with the OBS data demonstrate that refraction interferometry can sometimes more than quadruple the number of usable traces, increase the source-receiver offsets, fill in the receiver line with a denser distribution of OBS stations, and provide more reliable picking of first arrivals. Apotential liability

  19. OB protein binds specifically to the choroid plexus of mice and rats.

    Science.gov (United States)

    Devos, R; Richards, J G; Campfield, L A; Tartaglia, L A; Guisez, Y; van der Heyden, J; Travernier, J; Plaetinck, G; Burn, P

    1996-05-28

    Binding studies were conducted to identify the anatomical location of brain target sites for OB protein, the ob gene product. 125I-labeled recombinant mouse OB protein or alkaline phosphatase-OB fusion proteins were used for in vitro and in vivo binding studies. Coronal brain sections or fresh tissue from lean, obese ob/ob, and obese db/db mice as well as lean and obese Zucker rats were probed to identify potential central OB protein-binding sites. We report here that recombinant OB protein binds specifically to the choroid plexus. The binding of OB protein (either radiolabeled or the alkaline phosphatase-OB fusion protein) and its displacement by unlabeled OB protein was similar in lean, obese ob/ob, and obese db/db mice as well as lean and obese Zucker rats. These findings suggest that OB protein binds with high affinity to a specific receptor in the choroid plexus. After binding to the choroid plexus receptor, OB protein may then be transported across the blood-brain barrier into the cerebrospinal fluid. Alternatively, binding of OB protein to a specific receptor in the choroid plexus may activate afferent neural inputs to the neural network that regulates feeding behavior and energy balance or may result in the clearance or degradation of OB protein. The identification of the choroid plexus as a brain binding site for OB protein will provide the basis for the construction of expression libraries and facilitate the rapid cloning of the choroid plexus OB receptor. PMID:8643634

  20. ESTIMATION OF THE BURST LENGTH IN OBS NETWORKS

    Directory of Open Access Journals (Sweden)

    Pallavi S.

    2014-05-01

    Full Text Available This paper presents an overview of the optical burst switching (OBS and discusses the major components. In OBS, the length of the burst arriving at a particular node is unknown, and hence, node design is very complex. In OBS first control, packet is transmitted and reserve the path as in circuit switching, thereafter, the data bursts is transmitted. In this paper, a poisson arrival of packets is considered and estimation is made on the size of the burst length. The results presented in the paper clearly reveal that, the very large burst length is un-common. Therefore, most of the times, very short or average length burst is expected. Therefore it is concluded in this paper, buffering of burst at the contending nodes is a good option which increases the throughput and reduces the average delay. Finally, the buffering in conjunction with deflection of bursts will provide very effective solution.

  1. JAVOBS: A Flexible Simulator for OBS Network Architectures

    Directory of Open Access Journals (Sweden)

    Oscar Pedrola

    2010-02-01

    Full Text Available Since the OBS paradigm has become a potential candidate to cope with the needs of the future all optical networks, it has really caught the attention from both academia and industry worldwide. In this direction, OBS networks have been investigated under many different scenarios comprising numerous architectures and strategies. This heterogeneous context encouraged the development of various simulation tools. In this paper we present our novel Java-based OBS network simulator called JAVOBS. We discuss its architecture, study its performance and provide some exemplary results that point out its remarkable flexibility. This flexibility should permit an easy integration of upcoming new network protocol designs but also support changing and evolving research goals.

  2. Obs4MIPS: Satellite Observations for Model Evaluation

    Science.gov (United States)

    Ferraro, R.; Waliser, D. E.; Gleckler, P. J.

    2015-12-01

    This poster will review the current status of the obs4MIPs project, whose purpose is to provide a limited collection of well-established and documented datasets for comparison with Earth system models (https://www.earthsystemcog.org/projects/obs4mips/). These datasets have been reformatted to correspond with the CMIP5 model output requirements, and include technical documentation specifically targeted for their use in model output evaluation. There are currently over 50 datasets containing observations that directly correspond to CMIP5 model output variables. We will review recent additions to the obs4MIPs collection, and provide updated download statistics. We will also provide an update on changes to submission and documentation guidelines, the work of the WCRP Data Advisory Council (WDAC) Observations for Model Evaluation Task Team, and engagement with the CMIP6 MIP experiments.

  3. e-MERLIN 21cm constraints on the mass-loss rates of OB stars in Cyg OB2

    CERN Document Server

    Morford, Jack; Prinja, Raman; Blomme, Ronnie; Yates, Jeremy

    2016-01-01

    We present e-MERLIN 21 cm (L-band) observations of single luminous OB stars in the Cygnus OB2 association, from the COBRaS Legacy programme. The radio observations potentially offer the most straightforward, least model-dependent, determinations of mass-loss rates, and can be used to help resolve current discrepancies in mass-loss rates via clumped and structured hot star winds. We report here that the 21 cm flux densities of O3 to O6 supergiant and giant stars are less than ~ 70 microJy. These fluxes may be translated to `smooth' wind mass-loss upper limits of ~ 4.4 - 4.8 x 10^(-6) M_sol/yr for O3 supergiants and < 2.9 x 10^(-6) M_sol/yr for B0 to B1 supergiants. The first ever resolved 21 cm detections of the hypergiant (and LBV candidate) Cyg OB2 #12 are discussed; for multiple observations separated by 14 days, we detect a ~ 69% increase in its flux density. Our constraints on the upper limits for the mass-loss rates of evolved OB stars in Cyg OB2 support the model that the inner wind region close to t...

  4. Variable time-period optical switching: a novel OBS implementation

    Institute of Scientific and Technical Information of China (English)

    Jinsong Zhang(张劲松); Mingcui Cao(曹明翠); Fengguang Luo(罗风光); Tao Chen(陈涛)

    2003-01-01

    In this paper, we proposed a novel optical switching method based on optical burst switching (OBS), we call it variable time-period optical switching (VTPOS). It can both support circuit services and other immerged packet services. It has better usability of bandwidth, shorter offset and latency time than others of unidirectional transport signaling mechanisms for OBS. It supports deflection switching for improve blocking performance without the need of schedule buffer. It introduces a time pointer and phase indicator that made synchronous more precisely and requires less guard time, it also classifies the different services classes with a relative QoS model.

  5. Marine TAIGER OBS Experiment and its future prospects

    Science.gov (United States)

    Lee, C.; Wang, T.; van Avendonk, H. J.; Huang, Y.; Lin, J.; Lallemand, S.; Klingelhoeher, F.

    2009-12-01

    A total of 260 OBSs were deployed in the marine TAIGER program from late March to late July, 2009. These data were collected by US Columbia University’s R/V Langseth as the big-power seismic shooting ship and 10 Taiwanese ships to take terms for supporting of the OBS experiment in the entire seismic cruises. The OBS were provided by the National Taiwan Ocean University, French IFREMER and Scripps Institution of Oceanography. During these 4 months, we have worked around Taiwan in the South China Sea, Luzon Arc, East Taiwan and West Philippine Basin. All efforts are put together by many earth scientists from Taiwan, USA and France under one major purpose, to get a better understanding of the Taiwan mountain building processes. As a result, these new data will provide as a base to combine with many other disciplinal studies, such as the multi-channel seismic, land recorded seismometer data, gravity and magnetic as well as the natural earthquake data recorded by the OBS during the experiment time. Four very preliminary OBS data analyses will be presented in the same T25 postal section. Beside the research, we also carried out our teaching to our students on board a Taiwanese student training ship, Yu-Yin No.2. Therefore, an educational post is also to be shown in the ED01 section. Even the data analyses are in an early stage, but we are exciting about it. For example, 3 OBS profiles (T4, T5 and T6) in the East Taiwan were shot twice in normal and reversed directions with different shot intervals (30 and 60 seconds per shot). This exercise will be important to interpret the complicate collision/subduction structures in the East Taiwan. Two OBS profiles (T1 and T2) in the Luzon Arc were shot 5 times in the separated R/V Langseth cruises (due to the typhoon effects), again with different shot intervals (20 and 60 seconds per shot). These will provide us more opportunities to examine the collisional features in between Taiwan and Luzon. One OBS long profile (550 km) was

  6. IFN-γ secretion in gut of Ob/Ob mice after vertical sleeve gastrectomy and its function in weight loss mechanism.

    Science.gov (United States)

    Du, Jin-Peng; Wang, Geng; Hu, Chao-Jie; Wang, Qing-Bo; Li, Hui-Qing; Xia, Wen-Fang; Shuai, Xiao-Ming; Tao, Kai-Xiong; Wang, Guo-Bin; Xia, Ze-Feng

    2016-06-01

    Vertical sleeve gastrectomy (VSG) is becoming more and more popular among the world. Despite its dramatic efficacy, however, the mechanism of VSG remains largely undetermined. This study aimed to test interferon (IFN)-γ secretion n of mesenteric lymph nodes in obese mice (ob/ob mice), a model of VSG, and its relationship with farnesoid X receptor (FXR) expression in the liver and small intestine, and to investigate the weight loss mechanism of VSG. The wild type (WT) mice and ob/ob mice were divided into four groups: A (WT+Sham), B (WT+VSG), C (ob/ob+Sham), and D (ob/ob+VSG). Body weight values were monitored. The IFN-γ expression in mesenteric lymph nodes of ob/ob mice pre- and post-operation was detected by flow cytometry (FCM). The FXR expression in the liver and small intestine was detected by Western blotting. The mouse AML-12 liver cells were stimulated with IFN-γ at different concentrations in vitro. The changes of FXR expression were also examined. The results showed that the body weight of ob/ob mice was significantly declined from (40.6±2.7) g to (27.5±3.8) g on the 30th day after VSG (Psecretion of IFN-γ in mesenteric lymph nodes of ob/ob mice than that pre-operation (Psmall intestine after VSG were respectively 0.97±0.07 and 0.84±0.07 fold of GAPDH, which were significantly higher than pre-operative levels of 0.50±0.06 and 0.48±0.06 respectively (Psecretion of mesenteric lymph nodes, which then increases the FXR expression of the liver and small intestine.

  7. Octonionic Representations of GL(8,R) and GL(4,C)

    OpenAIRE

    Stefano De LeoDip. di Fisica, INFN, Lecce; Khaled Abdel-Khalek(Dip. di Fisica, INFN, Lecce)

    2015-01-01

    Octonionic algebra being nonassociative is difficult to manipulate. We introduce left-right octonionic barred operators which enable us to reproduce the associative GL(8,R) group. Extracting the basis of GL(4,C), we establish an interesting connection between the structure of left-right octonionic barred operators and generic 4x4 complex matrices. As an application we give an octonionic representation of the 4-dimensional Clifford algebra.

  8. Secure Optical Internet: A Novel Attack Prevention Mechanism for an OBS node in TCP/OBS Networks

    Directory of Open Access Journals (Sweden)

    K. Muthuraj

    2013-01-01

    Full Text Available Optical Internet has become a strong development and its commercial use is growing rapidly. Due to transparency and virtual sharing infrastructure, they provide ultra-fast data rates with the help of optical burst switching technology, which transmits data in the form of bursts. From the security perspective, one of the OBS nodes in the optical network is compromised, causes the vulnerability. This paper is dealt to identify the vulnerabilities and named as burst hijacking attack and provide the prevention mechanism for the same. The NSFnet 14 nodes and the ns2 simulator with modified nOBS patch is used to simulate and verify the security parameters.

  9. Sitagliptin can inhibit the development of hepatic steatosis in high-fructose diet-fed ob/ob mice

    OpenAIRE

    Sujishi, Tetsuya; Fukunishi, Shinya; Ii, Masaaki; Nakamura, Ken; Yokohama, Keisuke; Ohama, Hideko; Tsuchimoto, Yusuke; Asai, Akira; Tsuda, Yasuhiro; Higuchi, Kazuhide

    2015-01-01

    The beneficial effect of dipeptidyl peptidase-4 inhibition on diet-induced extra-pancreatic effects, especially on liver tissue remains poorly understood. Thus, we made the experimental designs as follows; five-week-old male ob/ob mice, which develop type 2 diabetic mellitus and nonalcoholic fatty liver disease by taking a high-carbohydrate diet (HCD), were divided into a group in which a HCD was given for 8 weeks as control, and another in which a HCD added with 0.0018% sitagliptin was given...

  10. Anti-obesity activity of diglyceride containing conjugated linoleic acid in C57BL/6J ob/ob mice

    OpenAIRE

    Hue, Jin-Joo; Lee, Ki Nam; Jeong, Jae-Hwang; Lee, Sang-Hwa; Lee, Young Ho; Jeong, Seong-woon; Nam, Sang Yoon; Yun, Young Won; Lee, Beom Jun

    2009-01-01

    This study was to investigate the anti-obesity effects of diglyceride (DG)-conjugated linoleic acid (CLA) containing 22% CLA as fatty acids in C57BL/6J ob/ob male mice. There were four experimental groups including vehicle control, DG, CLA, and DG-CLA. The test solutions of 750 mg/kg dose were orally administered to the mice everyday for 5 weeks. CLA treatments significantly decreased mean body weight in the obese mice throughout the experimental period compared to the control (p < 0.01). All...

  11. ADC Module built for an ocean bottom seismometer (OBS)

    OpenAIRE

    Carreras, Normandino; Shariat Panahi, Shahram; Manuel Lázaro, Antonio

    2010-01-01

    This paper presents the new data acquisition system designed for autonomous Ocean Bottom Seismometers (OBS) to study the earth dynamics and internal structure. This part is the responsible to acquire the signals from two different sensors to be processed. The analog-to-digital converter module is based on input amplifiers, modulator and digital filter.

  12. MUG-OBS - Multiparameter Geophysical Ocean Bottom System : a new instrumental approach to monitor earthquakes.

    Science.gov (United States)

    hello, yann; Charvis, Philippe; Yegikyan, Manuk; verfaillie, Romain; Rivet, Diane

    2016-04-01

    Real time monitoring of seismic activity is a major issue for early warning of earthquakes and tsunamis. It can be done using regional scale wired nodes, such as Neptune in Canada and in the U.S, or DONET in Japan. Another approach to monitor seismic activity at sea is to deploying repeatedly OBS array like during the amphibious Cascadia Initiative (four time 1-year deployments), the Japanese Pacific Array (broadband OBSs "ocean-bottom broadband dispersion survey" with 2-years autonomy), the Obsismer program in the French Lesser Antilles (eight time 6-months deployments) and the Osisec program in Ecuador (four time 6-months deployments). These autonomous OBSs are self-recovered or recovered using an ROV. These systems are costly including ship time, and require to recover the OBS before to start working on data. Among the most recent alternative we developed a 3/4 years autonomy ocean bottom system with 9 channels (?) allowing the acquisition of different seismic or environmental parameters. MUG-OBS is a free falling instrument rated down to 6000 m. The installation of the sensor is monitored by acoustic commands from the surface and a health bulletin with data checking is recovered by acoustic during the installation. The major innovation is that it is possible to recover the data any time on demand (regularly every 6-months or after a crisis) using one of the 6 data-shuttles released from the surface by acoustic command using a one day fast cruise boat of opportunity. Since sensors stayed at the same location for 3 years, it is a perfect tool to monitor large seismic events, background seismic activity and aftershock distribution. Clock, drift measurement and GPS localization is automatic when the shuttle reaches the surface. For remote areas, shuttles released automatically and a seismic events bulletin is transmitted. Selected data can be recovered by two-way Iridium satellite communication. After a period of 3 years the main station is self-recovered by

  13. An anomalous extinction law in the Cep OB3b young cluster: Evidence for dust processing during gas dispersal

    Energy Technology Data Exchange (ETDEWEB)

    Allen, Thomas S.; Prchlik, Jakub J.; Megeath, S. Thomas [University of Toledo, Ritter Astrophysical Observatory, Department of Physics and Astronomy, Toledo, OH 43606 (United States); Gutermuth, Robert A. [Five College Astronomy Department, Smith College, Northampton, MA 01063 (United States); Pipher, Judith L. [Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627 (United States); Naylor, Tim [School of Physics, University of Exeter, Exeter, UK EX4 4QL (United Kingdom); Jeffries, R. D. [Astrophysics Group, School of Physical and Geographical Sciences, Keele University, Keele, Staffordshire, UK ST5 5BG (United Kingdom)

    2014-05-10

    We determine the extinction law through Cep OB3b, a young cluster of 3000 stars undergoing gas dispersal. The extinction is measured toward 76 background K giants identified with MMT/Hectospec spectra. Color excess ratios were determined toward each of the giants using V and R photometry from the literature, g, r, i, and z photometry from the Sloan Digital Sky Survey and J, H, and K{sub s} photometry from the Two Micron All Sky Survey. These color excess ratios were then used to construct the extinction law through the dusty material associated with Cep OB3b. The extinction law through Cep OB3b is intermediate between the R{sub V} = 3.1 and R{sub V} = 5 laws commonly used for the diffuse atomic interstellar medium and dense molecular clouds, respectively. The dependence of the extinction law on line-of-sight A{sub V} is investigated and we find the extinction law becomes shallower for regions with A{sub V} > 2.5 mag. We speculate that the intermediate dust law results from dust processing during the dispersal of the molecular cloud by the cluster.

  14. ObsPy: A Python Toolbox for Seismology

    Science.gov (United States)

    Wassermann, J. M.; Krischer, L.; Megies, T.; Barsch, R.; Beyreuther, M.

    2013-12-01

    Python combines the power of a full-blown programming language with the flexibility and accessibility of an interactive scripting language. Its extensive standard library and large variety of freely available high quality scientific modules cover most needs in developing scientific processing workflows. ObsPy is a community-driven, open-source project extending Python's capabilities to fit the specific needs that arise when working with seismological data. It a) comes with a continuously growing signal processing toolbox that covers most tasks common in seismological analysis, b) provides read and write support for many common waveform, station and event metadata formats and c) enables access to various data centers, webservices and databases to retrieve waveform data and station/event metadata. In combination with mature and free Python packages like NumPy, SciPy, Matplotlib, IPython, Pandas, lxml, and PyQt, ObsPy makes it possible to develop complete workflows in Python, ranging from reading locally stored data or requesting data from one or more different data centers via signal analysis and data processing to visualization in GUI and web applications, output of modified/derived data and the creation of publication-quality figures. All functionality is extensively documented and the ObsPy Tutorial and Gallery give a good impression of the wide range of possible use cases. ObsPy is tested and running on Linux, OS X and Windows and comes with installation routines for these systems. ObsPy is developed in a test-driven approach and is available under the LGPLv3 open source licence. Users are welcome to request help, report bugs, propose enhancements or contribute code via either the user mailing list or the project page on GitHub.

  15. The stellar association around Gamma Velorum and its relationship with Vela OB2

    CERN Document Server

    Jeffries, R D; Walter, F M; Pozzo, M P; Devey, C R

    2008-01-01

    We present the results of a photometric BVI survey of 0.9 square degrees around the Wolf-Rayet binary gamma^2 Vel and its early-type companion gamma^1 Vel. Several hundred PMS stars are identified and the youth of a subset of these is confirmed by the presence of lithium, H-alpha emission and X-ray activity. We show that the PMS stars are kinematically coherent and spatially concentrated around gamma Vel. The PMS stars have similar proper motions to gamma Vel, to main-sequence stars around gammaVel and to early-type stars of the wider Vela OB2 association of which gamma^2 Vel is the brightest member. The ratio of main-sequence stars to low-mass (0.1-0.6 Msun) PMS stars is consistent with a Kroupa mass function. Main-sequence fitting to stars around gamma Vel gives a distance modulus of 7.76+/-0.07 mag, consistent with a similarly-determined distance for Vela OB2 and with interferometric distances to gamma^2 Vel. High-mass stellar models indicate an age of 3-4 Myr for gamma^2 Vel, but the low-mass PMS stars ha...

  16. Effects of caloric restriction on O-GlcNAcylation, Ca(2+) signaling, and learning impairment in the hippocampus of ob/ob mice.

    Science.gov (United States)

    Jeon, Byeong Tak; Heo, Rok Won; Jeong, Eun Ae; Yi, Chin-Ok; Lee, Jong Youl; Kim, Kyung Eun; Kim, Hwajin; Roh, Gu Seob

    2016-08-01

    Diabetes may adversely affect cognitive function and, conversely, caloric restriction (CR) increases longevity and improves memory. To shed light on the unknown underlying mechanisms involved in these observations, we examined the effects of CR on serum metabolic parameters and hippocampal protein expression in the ob/ob mice model of obesity-induced diabetes. We found that CR reduced hepatic steatosis and insulin resistance in ob/ob mice. In addition, CR increased the levels of hippocampal O-linked-N-acetylglucosamine (O-GlcNAc) and GlcNAc transferase and decreased the expression of calcium/calmodulin-dependent protein kinase II, lipocalin-2, and phosphorylated tau. Furthermore, CR lessened the learning deficits that are typically seen in ob/ob mice. These findings indicate that CR may reverse obesity-related brain glucose impairment and intracellular Ca(2+) dysfunction and relieve learning impairment associated with diabetes. PMID:27318140

  17. iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.

    Science.gov (United States)

    Deng, Xiuling; Wang, Jiliang; Jiao, Li; Utaipan, Tanyarath; Tuma-Kellner, Sabine; Schmitz, Gerd; Liebisch, Gerhard; Stremmel, Wolfgang; Chamulitrat, Walee

    2016-05-01

    PLA2G6 or GVIA calcium-independent PLA2 (iPLA2β) is identified as one of the NAFLD modifier genes in humans, and thought to be a target for NAFLD therapy. iPLA2β is known to play a house-keeping role in phospholipid metabolism and remodeling. However, its role in NAFLD pathogenesis has not been supported by results obtained from high-fat feeding of iPLA2β-null (PKO) mice. Unlike livers of human NAFLD and genetically obese rodents, fatty liver induced by high-fat diet is not associated with depletion of hepatic phospholipids. We therefore tested whether iPLA2β could regulate obesity and hepatic steatosis in leptin-deficient mice by cross-breeding PKO with ob/ob mice to generate ob/ob-PKO mice. Here we observed an improvement in ob/ob-PKO mice with significant reduction in serum enzymes, lipids, glucose, insulin as well as improved glucose tolerance, and reduction in islet hyperplasia. The improvement in hepatic steatosis measured by liver triglycerides, fatty acids and cholesterol esters was associated with decreased expression of PPARγ and de novo lipogenesis genes, and the reversal of β-oxidation gene expression. Notably, ob/ob livers contained depleted levels of lysophospholipids and phospholipids, and iPLA2β deficiency in ob/ob-PKO livers lowers the former, but replenished the latter particularly phosphatidylethanolamine (PE) and phosphatidylcholine (PC) that contained arachidonic (AA) and docosahexaenoic (DHA) acids. Compared with WT livers, PKO livers also contained increased PE and PC containing AA and DHA. Thus, iPLA2β deficiency protected against obesity and ob/ob fatty liver which was associated with hepatic fatty-acyl phospholipid remodeling. Our results support the deleterious role of iPLA2β in severe obesity associated NAFLD.

  18. OB stars in the Leading Arm of the Magellanic Stream

    CERN Document Server

    Bidin, C Moni; Mendez, R A; Girard, T M; Vieira, K; Korchagin, V I; van Altena, W F

    2013-01-01

    We present our spectroscopic program aimed to study some new interesting features recently discovered in the Magellanic Cloud System. These were revealed by the spatial distribution of OB-type candidate stars, selected based on UV, optical and IR photometry and proper motions from existing large-area catalogs. As a pilot study of our project, we are studying OB-star candidates in the Leading Arm (LA) of the Magellanic Stream, a gaseous tidal structure with no stellar counterpart known so far. Our targets group in three clumps near regions of high HI density in the LA. If confirmed, these young stars would evidence recent star formation in the LA, and they would help better understand and constrain the formation of the LA and its interactions with the Milky Way.

  19. Simulation Model for OBS Contention Avoidance Routing Strategies

    Science.gov (United States)

    Barradas, Alvaro L.; Do Carmo R. Medeiros, Maria

    Optical burst switching (OBS) provides a feasible paradigm for the next IP over optical network backbones. However, due to its bufferless nature, OBS efficiency can be reduced by resource contention leading to burst loss. Several methods have been proposed to address this problem, most of them relying on reactive mechanisms which increase the complexity of core nodes, hampering scalability. In this work we consider a preventive traffic engineering approach for contention resolution which provides source routing with the objective of minimizing contention at the transmission links considering only topological information. This paper presents a simulation model aimed at the evaluation of different offline routing strategies in terms of burst contention. The simulation model is used to compare the performance of different novel path selection strategies with the traditional shortest path routing approach. Results confirm that the proposed strategies are effective in reducing the overall blocking and the model is feasible for the proposed QoS evaluation.

  20. Velocity Space of Galactic O-B Stars

    Institute of Scientific and Technical Information of China (English)

    Zi Zhu

    2006-01-01

    Based on the Hipparcos proper motions and available radial velocity data of O-B stars, we have re-examined the local kinematical structure of the young disk population of ~ 1500 O-B stars not including the Gould-belt stars. A systematic warping motion of the stars about the direction to the Galactic center has been reconfirmed. A negative K-term implying a systematic contraction of stars in the solar vicinity has been detected. Two different distance scales are used in order to find out their impact on the kinematical parameters, and we conclude that the adopted distance scale plays an important role in characterizing the kinematical parameters at the present level of the measurement uncertainty.

  1. Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.

    Directory of Open Access Journals (Sweden)

    Neira Sáinz

    Full Text Available Leptin improves insulin sensitivity in skeletal muscle. Our goal was to determine whether proteins controlling GLUT4 traffic are altered by leptin deficiency and in vivo leptin administration in skeletal muscle of wild type and ob/ob mice. Leptin-deficient ob/ob mice were divided in three groups: control, leptin-treated (1 mg/kg/d and leptin pair-fed ob/ob mice. Microarray analysis revealed that 1,546 and 1,127 genes were regulated by leptin deficiency and leptin treatment, respectively. Among these, we identified 24 genes involved in intracellular vesicle-mediated transport in ob/ob mice. TBC1 domain family, member 1 (Tbc1d1, a negative regulator of GLUT4 translocation, was up-regulated (P = 0.001 in ob/ob mice as compared to wild types. Importantly, leptin treatment reduced the transcript levels of Tbc1d1 (P<0.001 and Tbc1d4 (P = 0.004 in the leptin-treated ob/ob as compared to pair-fed ob/ob animals. In addition, phosphorylation levels of TBC1D1 and TBC1D4 were enhanced in leptin-treated ob/ob as compared to control ob/ob (P = 0.015 and P = 0.023, respectively and pair-fed ob/ob (P = 0.036 and P = 0.034, respectively mice. Despite similar GLUT4 protein expression in wild type and ob/ob groups a different immunolocalization of this protein was evidenced in muscle sections. Leptin treatment increased GLUT4 immunoreactivity in gastrocnemius and extensor digitorum longus sections of leptin-treated ob/ob mice. Moreover, GLUT4 protein detected in immunoprecipitates from TBC1D4 was reduced by leptin replacement compared to control ob/ob (P = 0.013 and pair-fed ob/ob (P = 0.037 mice. Our findings suggest that leptin enhances the intracellular GLUT4 transport in skeletal muscle of ob/ob animals by reducing the expression and activity of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4.

  2. Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice

    Science.gov (United States)

    Sáinz, Neira; Rodríguez, Amaia; Catalán, Victoria; Becerril, Sara; Ramírez, Beatriz; Lancha, Andoni; Burgos-Ramos, Emma; Gómez-Ambrosi, Javier; Frühbeck, Gema

    2012-01-01

    Leptin improves insulin sensitivity in skeletal muscle. Our goal was to determine whether proteins controlling GLUT4 traffic are altered by leptin deficiency and in vivo leptin administration in skeletal muscle of wild type and ob/ob mice. Leptin-deficient ob/ob mice were divided in three groups: control, leptin-treated (1 mg/kg/d) and leptin pair-fed ob/ob mice. Microarray analysis revealed that 1,546 and 1,127 genes were regulated by leptin deficiency and leptin treatment, respectively. Among these, we identified 24 genes involved in intracellular vesicle-mediated transport in ob/ob mice. TBC1 domain family, member 1 (Tbc1d1), a negative regulator of GLUT4 translocation, was up-regulated (P = 0.001) in ob/ob mice as compared to wild types. Importantly, leptin treatment reduced the transcript levels of Tbc1d1 (P<0.001) and Tbc1d4 (P = 0.004) in the leptin-treated ob/ob as compared to pair-fed ob/ob animals. In addition, phosphorylation levels of TBC1D1 and TBC1D4 were enhanced in leptin-treated ob/ob as compared to control ob/ob (P = 0.015 and P = 0.023, respectively) and pair-fed ob/ob (P = 0.036 and P = 0.034, respectively) mice. Despite similar GLUT4 protein expression in wild type and ob/ob groups a different immunolocalization of this protein was evidenced in muscle sections. Leptin treatment increased GLUT4 immunoreactivity in gastrocnemius and extensor digitorum longus sections of leptin-treated ob/ob mice. Moreover, GLUT4 protein detected in immunoprecipitates from TBC1D4 was reduced by leptin replacement compared to control ob/ob (P = 0.013) and pair-fed ob/ob (P = 0.037) mice. Our findings suggest that leptin enhances the intracellular GLUT4 transport in skeletal muscle of ob/ob animals by reducing the expression and activity of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4. PMID:22253718

  3. Ensuring QOS Gurantees in a hybrid OCS/OBS Network

    OpenAIRE

    Sunish Kumar O S

    2012-01-01

    The bursting aggregation assembly in edge nodes is one of the key technologies in OBS (Optical Burst Switching) network, which has a direct impact on flow characteristics and packet loss rate. An opticalburst assembly technique supporting QoS is presented through this paper, which can automatically adjust the threshold along with the increasing and decreasing volume of business, reduce the operational burst, and generate corresponding BDP (Burst Data Packet) and BCP (Burst Control Packet). ...

  4. Ensuring QOS Guarantees in a Hybrid OCS/OBS Network

    OpenAIRE

    S, Sunish Kumar O

    2012-01-01

    The bursting aggregation assembly in edge nodes is one of the key technologies in OBS (Optical Burst Switching) network, which has a direct impact on flow characteristics and packet loss rate. An optical burst assembly technique supporting QoS is presented through this paper, which can automatically adjust the threshold along with the increasing and decreasing volume of business, reduce the operational burst, and generate corresponding BDP (Burst Data Packet) and BCP (Burst Control Packet). I...

  5. Time base stability of ocean bottom seismometers (OBS)

    OpenAIRE

    Shariat Panahi, Shahram; Manuel Lázaro, Antonio; Corrêa Alegría, Francisco

    2009-01-01

    During the past decades, Ocean Bottom Seismometers (OBS) have played a key role in permanent seismic activity monitoring at sea as well as allowing a better understating of the earth interior. Data collected by the instrument can provide information on the ocean bottom sub-layers down to a depth of 40 km beneath the ocean floor. The accuracy of the results directly depends on the temperature stability of the crystal used as the main time base of the equipment. This paper pre...

  6. An assessment of the MCNP4C weight window

    Energy Technology Data Exchange (ETDEWEB)

    Christopher N. Culbertson; John S. Hendricks

    1999-12-01

    A new, enhanced weight window generator suite has been developed for MCNP version 4C. The new generator correctly estimates importances in either a user-specified, geometry-independent, orthogonal grid or in MCNP geometric cells. The geometry-independent option alleviates the need to subdivide the MCNP cell geometry for variance reduction purposes. In addition, the new suite corrects several pathologies in the existing MCNP weight window generator. The new generator is applied in a set of five variance reduction problems. The improved generator is compared with the weight window generator applied in MCNP4B. The benefits of the new methodology are highlighted, along with a description of its limitations. The authors also provide recommendations for utilization of the weight window generator.

  7. Photoevaporating Proplyd-like objects in Cygnus OB2

    CERN Document Server

    Wright, Nicholas J; Drew, Janet E; Guarcello, Mario G; Gutermuth, Robert A; Hora, Joseph L; Kraemer, Kathleen E

    2012-01-01

    We report the discovery of ten proplyd-like objects in the vicinity of the massive OB association Cygnus OB2. They were discovered in IPHAS H-Alpha images and are clearly resolved in broad-band HST/ACS, near-IR and Spitzer mid-IR images. All exhibit the familiar tadpole shape seen in photoevaporating objects such as the Orion proplyds, with a bright ionization front at the head facing the central cluster of massive stars, and a tail stretching in the opposite direction. Many also show secondary ionization fronts, complex tail morphologies or multiple heads. We consider the evidence that these are either proplyds or `evaporating gaseous globules' (EGGs) left over from a fragmenting molecular cloud, but find that neither scenario fully explains the observations. Typical sizes are 50,000--100,000 AU, larger than the Orion proplyds, but in agreement with the theoretical scaling of proplyd size with distance from the ionizing source. These objects are located at projected separations of 6-14pc from the OB associat...

  8. Rotation of young stars in Cepheus OB3b

    CERN Document Server

    Littlefair, S P; Mayne, N J; Saunders, Eric S; Jeffries, R D

    2009-01-01

    We present a photometric study of I-band variability in the young association Cepheus OB3b. The study is sensitive to periodic variability on timescales of less than a day, to more than 20 days. After rejection of contaminating objects using V, I, R and narrowband H-alpha photometry, we find 475 objects with measured rotation periods, which are very likely pre-main-sequence members of the Cep OB3b star forming region. We revise the distance and age to Cep OB3b, putting it on the self-consistent age and distance ladder of Mayne & Naylor (2008). This yields a distance modulus of 8.8 +/- 0.2 mags, corresponding to a distance of 580 +/- 60 pc, and an age of 4-5Myrs. The rotation period distribution confirms the general picture of rotational evolution in young stars, exhibiting both the correlation between accretion (determined in this case through narrowband H-alpha photometry) and rotation expected from disc locking, and the dependence of rotation upon mass that is seen in other star forming regions. However...

  9. Fault Tolerant Congestion based Algorithms in OBS Network

    Directory of Open Access Journals (Sweden)

    Hardeep Singh

    2011-12-01

    Full Text Available In Optical Burst Switched networks, each light path carry huge amount of traffic, path failures may damage the user application. Hence fault-tolerance becomes an important issue on these networks. Blocking probability is a key index of quality of service in Optical Burst Switched (OBS network. The Erlang formula has been used extensively in the traffic engineering of optical communication to calculate the blocking probability. The paper revisits burst contention resolution problems in OBS networks. When the network is overloaded, no contention resolution scheme would effectively avoid the collision and cause blocking. It is important to first decide, a good routing algorithm and then to choose a wavelength assignment scheme. In this paper we have developed two algorithms, Fault Tolerant Optimized Blocking Algorithm (FTOBA and Fault Tolerant Least Congestion Algorithm (FTLCA and then compare the performance of these algorithms on the basis of blocking probability. These algorithms are based upon the congestion on path in OBS network and based on the simulation results, we shows that the reliable and fault tolerant routing algorithms reduces the blocking probability.

  10. Cygnus OB2 DANCe: A high-precision proper motion study of the Cygnus OB2 association

    Science.gov (United States)

    Wright, Nicholas J.; Bouy, Herve; Drew, Janet E.; Sarro, Luis Manuel; Bertin, Emmanuel; Cuillandre, Jean-Charles; Barrado, David

    2016-08-01

    We present a high-precision proper motion study of 873 X-ray and spectroscopically selected stars in the massive OB association Cygnus OB2 as part of the DANCe project. These were calculated from images spanning a 15 yr baseline and have typical precisions <1 mas yr-1. We calculate the velocity dispersion in the two axes to be σ _α (c) = 13.0^{+0.8}_{-0.7} and σ _δ (c) = 9.1^{+0.5}_{-0.5} km s-1, using a two-component, two-dimensional model that takes into account the uncertainties on the measurements. This gives a three-dimensional velocity dispersion of σ3D = 17.8 ± 0.6 km s-1 implying a virial mass significantly larger than the observed stellar mass, confirming that the association is gravitationally unbound. The association appears to be dynamically unevolved, as evidenced by considerable kinematic substructure, non-isotropic velocity dispersions and a lack of energy equipartition. The proper motions show no evidence for a global expansion pattern, with approximately the same amount of kinetic energy in expansion as there is in contraction, which argues against the association being an expanded star cluster disrupted by process such as residual gas expulsion or tidal heating. The kinematic substructures, which appear to be close to virial equilibrium and have typical masses of 40-400 M⊙, also do not appear to have been affected by the expulsion of the residual gas. We conclude that Cyg OB2 was most likely born highly substructured and globally unbound, with the individual subgroups born in (or close to) virial equilibrium, and that the OB association has not experienced significant dynamical evolution since then.

  11. Analiza posedanja magnetno občutljivih mikrodelcev in določitev magnetne občutljivosti

    OpenAIRE

    Černec, Dean

    2016-01-01

    Magistrska naloga podaja izsledke eksperimentov s posedanjem magnetno občutljivih mikrodelcev. Pri raziskavah, katerih namen je ugotavljanje različnih fizikalnih lastnosti delcev, se v praksi pogosto uporabljajo sedimentacijski procesi. Če se delci pri posedanju odzivajo tudi na delovanje zunanjega magnetnega polja, pa lahko določamo tudi njihove magnetne lastnosti. Začetne analize so bile narejene na podlagi eksperimentov s posedanjem steklenih kroglic, za kontrolo končnih hitrosti posedanja...

  12. Study of Eclipsing Binary and Multiple Systems in OB Associations IV: Cas OB6 Member DN Cas

    Science.gov (United States)

    Bakış, V.; Bakış, H.; Bilir, S.; Eker, Z.

    2016-09-01

    An early-type, massive, short-period (Porb=2d.310951) eclipsing spectroscopic binary DN Cas has been re-visited with new spectral and photometric data. The masses and radii of the components have been obtained as M1=19.04± 0.07 M⊙, M2=13.73± 0.05 M⊙ and R1=7.22± 0.06 R⊙, R2=5.79± 0.06 R⊙, respectively. Both components present synchronous rotation (Vrot1=160 km s-1, Vrot2=130 km s-1) with their orbit. Orbital period analysis yielded a physically bound additional component in the system with a minimum mass of M3=0.88 M⊙ orbiting in an eccentric orbit (e = 0.37 ± 0.2) with an orbital period of P 12 = 42 ± 9 yr. High precision absolute parameters of the system allowed us to derive a distance to DN Cas as 1.7 ± 0.2 kpc which locates the system within the borders of the Cas OB6 association (d = 1.8 kpc). The space velocities and the age of DN Cas are in agreement with those of Cas OB6. The age of DN Cas (τ = 3-5 Myr) is found to be 1-2 Myr older than the embedded clusters (IC 1795, IC 1805, and IC 1848) in the Cas OB6 association, which implies a sequential star formation in the association.

  13. Optical and radio properties of 4C galaxies

    International Nuclear Information System (INIS)

    The relations between the optical and radio properties of a sample of 4C radio galaxies of intermediate radio luminosity have been investigated. Optical spectra were taken with the Hale 5-m telescope and radio maps of a subset of the galaxies were made with the Cambridge 1-mile and 5-km telescopes. The optical activity of the nuclear region was characterized by the strength of the emission lines and by the luminosity of the non-thermal component obtained from a decomposition of the optical continuum into a non-thermal power law and the spectrum of a giant elliptical galaxy. The percentage of sources showing strong emission features is markedly less than for high-luminosity objects. The radio morphology appears to be closely related to the degree of optical activity, in that classical double sources have high activity whereas complex radio sources show little or no activity. This correlation is discussed in terms of (1) an intrinsic relationship between the energy spectrum of the relativistic electrons in the nucleus and the optical and radio properties of the galaxy, and (2) the modifications of this relationship due to the motion of the galaxy through the intergalactic medium. (author)

  14. Effect of the Ti/B4C mole ratio on the reaction products and reaction mechanism in an Al–Ti–B4C powder mixture

    International Nuclear Information System (INIS)

    The effect of the Ti/B4C mole ratio on the fabrication behavior of Al composites is investigated using Al–Ti–B4C powder mixtures as reactants. The quick spontaneous infiltration (QSI) process combined with the combustion reaction and DTA analysis were used. According to the thermodynamic predictions, which are verified in the experimental results, TiB2 is formed in all the samples whereas TiC is only formed in reactants with a Ti/B4C mole ratio of more than two. The C atoms from the reacted B4C do not move into TiC but instead they move into Al3BC or Al4C3 when the Ti/B4C mole ratio is less than two. In addition, the reaction mechanism with a Ti/B4C mole ratio of 0.75 is investigated extensively. - Highlights: • The critical role of the Ti/B4C mole ratio on the reaction products of Al–Ti–B4C was studied using experiments. • The experimental results are also supported by thermodynamic calculations presented in this paper. • The reaction mechanism with a Ti/B4C mole ratio of 0.75 is investigated extensively

  15. NEAR-IR Spectroscopy of Young Stars in the Braid Nebula Star Formation Region in Cygnus Ob7

    OpenAIRE

    Aspin, Colin; Beck, Tracy L.; Pyo, Tae-Soo; Davis, Chris J.; Schieven, G. M.; Khanzadyan, Tigran; Magakian, Tigran; Movsessian, Tigran; NIkogossian, Elena G.; Mitchison, Sharon; Smith, Michael D.

    2008-01-01

    We present 1.4 to 2.5 um integral field spectroscopy of 16 stars in the Braid Nebula star formation region in Cygnus OB7. These data forms one aspect of a large-scale multi-wavelength survey aimed at determining an unbiased estimate of the number, mass distribution, and evolutionary state of the young stars within this one square degree area of the previously poorly studied Lynds 1003 molecular cloud. Our new spectroscopic data, when combined with 2MASS near-IR photometry, provide evidence of...

  16. OBS FOMAR POOL: Gibraltar and ALERTES-RIM experiments.

    Science.gov (United States)

    Pazos, Antonio; Martín Davila, Jose; Buforn, Elisa; Cabieces, Roberto; Santos, Jose; Sandoval, Nicolas; Roca, Antoni; Dahm, Torsten

    2016-04-01

    The Eurasian-African plate boundary crosses the called "Ibero-Maghrebian" region from the San Vicente Cape (SW Portugal) to Tunisia including the south Iberia, Alboran Sea, and northern of Morocco and Algeria. The low convergence rate at this plate boundary produces a continuous moderate seismic activity of low magnitude and shallow depth, where the occurrence of large earthquakes is separated by long time intervals, even with associated tsunamis, like the 1755 Lisbon earthquake. In this region, there are also intermediate and very deep earthquakes. Due to the fact that part of the seismic activity is located at marine areas, and also because of the poor geographic azimuthal coverage at some zones provided by the land stations (specially in the SW of the San Vicente Cape area), Royal Spanish Navy Observatory (ROA) acquired three "LOSTERN" broad band (CMG-40T sensors) OBS, manufactured by KUM (Kiel, Germany), and, more recently (2014), the Complutense University of Madrid (UCM) acquired another three with Trillium 120 sensors. All of them conform the OBS FOMAR pool. Since January to November 2014, the FOMAR pool has been deployed along the Gibraltar strait (Gibraltar experiment), in collaboration with SECEGSA (Spanish society to study the fix communication through the Gibraltar Strait), to study the local microseismicity in the Gibraltar strait area. Also, since September 2015, the FOMAR pool has been deployed for 8 months in SW of the San Vicente Cape with an hexagonal array configuration as a part of ALERTES-RIM project. In this work the some preliminary results of the Gibraltar strait and ALERTES-RIM OBS experiment are shown.

  17. Effects of the switching time in OPS/OBS networks

    Institute of Scientific and Technical Information of China (English)

    Harald (φ)verby; Norvald Stol

    2004-01-01

    In this paper we present an analytical model, which considers the effects of the switching time on the network performance in service differentiated optical packet/burst switching (OPS/OBS) networks. Our results indicate that the switching time must be less than 10 % of the packet/burst duration in order to avoid any significant reductions in the network performance. Furthermore, regarding a network with full wavelength conversion, we show that the benefits of statistical resource sharing are almost non-existent for low priority traffic when the switching time is large.

  18. The object SNO 74 in the association Ara OB 1

    Science.gov (United States)

    Gyulbudaghian, A. L.

    2013-06-01

    The star formation region SNO 74 embedded in a dark cloud in the association Ara OB 1 is studied. This object is coupled to a compact HII region visible in the IR and to a close cluster of IR stars. 12CO(1-0) observations reveal the existence of red and blue molecular outflows; i.e., this is a bipolar outflow. An image taken with the SIMBA detector at 1.2 mm contains a second active region and a bridge lying to the W of the first active region and accompanied by strong absorption. The red molecular outflow is directed toward this second active region and the bridge.

  19. Research on the Four-Component Instructional Design Model (4C/ID)%四要素教学设计模型(4C/ID)研究

    Institute of Scientific and Technical Information of China (English)

    孙琼玲; 任翔

    2011-01-01

    通过对文献的研究和分析,目前国内关于4C/ID模型的研究主要关注:4C/ID模型的内涵、理论基础、构成要素以及4C/ID模型与其他模型的区别等;而国外的研究重点则是4C/ID模型在实践中的应用研究,从中我们可以得到一些启示.

  20. X-ray properties and interface study of B4C/Mo and B4C/Mo2C periodic multilayers

    Science.gov (United States)

    Choueikani, F.; Bridou, F.; Lagarde, B.; Meltchakov, E.; Polack, F.; Mercere, P.; Delmotte, F.

    2013-04-01

    We present a comparative study of B4C/Mo and B4C/Mo2C periodic multilayer structures deposited by magnetron sputtering. The characterization was performed by grazing incidence X-ray reflectometry at two different energies and high resolution transmission electron microscopy. The experimental results indicate the existence of an interdiffusion layer at the B4C-on-Mo interface in the B4C/Mo system. Thus, the B4C/Mo multilayers were modeled by an asymmetric structure with three layers in each period. The thickness of B4C-on-Mo interfacial layer was estimated about 1.1 nm. The B4C/Mo2C multilayers present less interdiffusion and are well modeled by a symmetric structure without interfacial layers. This study shows that B4C/Mo2C structure is an interesting alternative to B4C/Mo multilayer for X-ray optic applications.

  1. Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha

    DEFF Research Database (Denmark)

    Hwang, C S; Mandrup, S; MacDougald, O A;

    1996-01-01

    Like other adipocyte genes that are transcriptionally activated by CCAAT/enhancer binding protein alpha (C/EBP alpha) during preadipocyte differentiation, expression of the mouse obese (ob) gene is immediately preceded by the expression of C/EBP alpha. While the 5' flanking region of the mouse ob......, these findings implicate C/EBP alpha as a transcriptional activator of the ob gene promoter and identify the functional C/EBP binding site in the promoter....

  2. Reduction of obesity, as induced by leptin, reverses endothelial dysfunction in obese (Lep(ob)) mice

    Science.gov (United States)

    Winters, B.; Mo, Z.; Brooks-Asplund, E.; Kim, S.; Shoukas, A.; Li, D.; Nyhan, D.; Berkowitz, D. E.

    2000-01-01

    Obesity is a major health care problem and is associated with significant cardiovascular morbidity. Leptin, a neuroendocrine hormone released by adipose tissue, is important in modulating obesity by signaling satiety and increasing metabolism. Moreover, leptin receptors are expressed on vascular endothelial cells (ECs) and mediate angiogenesis. We hypothesized that leptin may also play an important role in vasoregulation. We investigated vasoregulatory mechanisms in the leptin-deficient obese (ob/ob) mouse model and determined the influence of leptin replacement on endothelial-dependent vasorelaxant responses. The direct effect of leptin on EC nitric oxide (NO) production was also tested by using 4, 5-diaminofluorescein-2 diacetate staining and measurement of nitrate and nitrite concentrations. Vasoconstrictor responses to phenylephrine, norepinephrine, and U-46619 were markedly enhanced in aortic rings from ob/ob mice and were modulated by NO synthase inhibition. Vasorelaxant responses to ACh were markedly attenuated in mesenteric microvessels from ob/ob mice. Leptin replacement resulted in significant weight loss and reversal of the impaired endothelial-dependent vasorelaxant responses observed in ob/ob mice. Preincubation of ECs with leptin enhanced the release of NO production. Thus leptin-deficient ob/ob mice demonstrate marked abnormalities in vasoregulation, including impaired endothelial-dependent vasodilation, which is reversed by leptin replacement. These findings may be partially explained by the direct effect of leptin on endothelial NO production. These vascular abnormalities are similar to those observed in obese, diabetic, leptin-resistant humans. The ob/ob mouse may, therefore, be an excellent new model for the study of the cardiovascular effects of obesity.

  3. Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer

    Institute of Scientific and Technical Information of China (English)

    Makoto Ishikawa; Joji Kitayama; Hirokazu Nagawa

    2006-01-01

    AIM: To examine the expression of leptin and its receptor, OB-R, in normal gastric mucosa and neoplasia.METHODS: By immunohistochemical staining using specific antibodies, we evaluated the expression of leptin and OB-R in 207 gastric carcinomas (100 early and 107 advanced carcinomas) and analyzed their relationship with clinicopathological features.RESULTS: Both normal gastric epithelium and carcinoma cells expressed a significant level of leptin. In cases with OB-R staining, carcinoma cells showed OB-Rpositive expression, but the intensity was weaker than that in normal mucosa. The expression of OB-R showed a significant correlation with the level of leptin expression. The expression levels of both leptin and OB-R tend ed to increase as the depth of tumor invasion or TMN stage increased (P < 0.01). Lymph node metastasis was detected in 49.5% (47/95) of leptin-strong cases and in 50.5% (48/95) of OB-R-positive cases, and the rate was 33% (37/112) in leptin-weak cases and 17% (19/112) in OB-R-negative cases. Both venous and lymphatic invasion also tended to be observed frequently in positive tumors as compared with negative tumors. Interestingly,in the 96 leptin- or OB-R-positive tumors, hematogenous metastasis was detected preoperatively in 3 (3.1%) patients. In contrast, none of the carcinomas that lacked expression of leptin and OB-R showed hematogenous metastasis.CONCLUSION: Overexpression of leptin and expression of OB-R may play a positive role in the process of progression in gastric cancer. Functional upregulation of leptin/OB-R may have a positive role in the development and initial phase of progression in gastric cancer.

  4. The Seismic Broad Band Western Mediterranean (wm) Network and the Obs Fomar Pool: Current state and Obs activities.

    Science.gov (United States)

    Pazos, Antonio; Davila, Jose Martin; Buforn, Elisa; Bezzeghoud, Mourad; Harnafi, Mimoun; Mattesini, Mauricio; Caldeira, Bento; Hanka, Winfried; El Moudnib, Lahcen; Strollo, Angelo; Roca, Antoni; Lopez de Mesa, Mireya; Dahm, Torsten; Cabieces, Roberto

    2016-04-01

    The Western Mediterranean (WM) seismic network started in 1996 as an initiative of the Royal Spanish Navy Observatory (ROA) and the Universidad Complutense de Madrid (UCM), with the collaboration of the GeoForschungsZentrum (GFZ) of Potsdam. A first broad band seismic station (SFUC) was installed close to Cádiz (South Spain). Since then, additional stations have been installed in the Ibero-Moghrebian region. In 2005, the "WM" code was assigned by the FDSN and new partners were jointed: Evora University (UEVO, Portugal), the Scientifique Institute of Rabat (ISRABAT, Morocco), and GFZ. Now days, the WM network is composed by 15 BB stations, all of them with Streckaisen STS-2 or STS-2.5 sensors, Quanterra or Earthdata digitizers and SeiscomP. Most them have co-installed a permanent geodetic GPS stations, and some them also have an accelerometer. There are 10 stations deployed in Spanish territory (5 in the Iberian peninsula, 1 in Balearic islands and 4 in North Africa Spanish places) with VSAT or Internet communications, 2 in Portugal (one of them without real time), and 3 in Morocco (2 VSAT and 1 ADSL). Additionally, 2 more stations (one in South Spain and one in Morocco) will be installed along this year. Additionally ROA has deployed a permanent real time VBB (CMG-3T: 360s) station at the Alboran Island. Due to the fact that part of the seismic activity is located at marine areas, and also because of the poor geographic azimuthal coverage at some zones provided by the land stations (specially in the SW of the San Vicente Cape area), ROA and UCM have acquired six broad band "LOBSTERN" OBS, manufactured by KUM (Kiel, Germany), conforming the OBS FOMAR pool. Three of them with CMG-40T sensor and the other with Trillium 120. These OBS were deployed along the Gibraltar strait since January to November 2014 to study the microseismicity in the Gibraltar strait area. In September 2015 FOMAR network has been deployed in SW of the San Vicente Cape for 8 months as a part of

  5. Ensuring QOS Gurantees in a hybrid OCS/OBS Network

    Directory of Open Access Journals (Sweden)

    Sunish Kumar O S

    2012-04-01

    Full Text Available The bursting aggregation assembly in edge nodes is one of the key technologies in OBS (Optical Burst Switching network, which has a direct impact on flow characteristics and packet loss rate. An opticalburst assembly technique supporting QoS is presented through this paper, which can automatically adjust the threshold along with the increasing and decreasing volume of business, reduce the operational burst, and generate corresponding BDP (Burst Data Packet and BCP (Burst Control Packet. In addition to theburst aggregation technique a packet recovery technique by restoration method is also described. The data packet loss due to the physical optical link failure is not currently included in the QoS descriptions. This link failure is also a severe problem which reduces the data throughput of the transmitter node. A mechanism for data recovery from this link failure is vital for guaranteeing the QoS demanded by each user. So this paper will also discusses a specific protocol for reducing the packet loss by utilizing the features of both optical circuit switching (OCS and Optical Burst switching (OBS techniques.

  6. The Massive Star Population of Cygnus OB2

    CERN Document Server

    Wright, Nicholas J; Mohr-Smith, Michael

    2015-01-01

    We have compiled a significantly updated and comprehensive census of massive stars in the nearby Cygnus OB2 association by gathering and homogenising data from across the literature. The census contains 169 primary OB stars, including 52 O-type stars and 3 Wolf-Rayet stars. Spectral types and photometry are used to place the stars in a Hertzprung-Russell diagram, which is compared to both non-rotating and rotating stellar evolution models, from which stellar masses and ages are calculated. The star formation history and mass function of the association are assessed, and both are found to be heavily influenced by the evolution of the most massive stars to their end states. We find that the mass function of the most massive stars is consistent with a `universal' power-law slope of Gamma = 1.3. The age distribution inferred from stellar evolutionary models with rotation and the mass function suggest the majority of star formation occurred more or less continuously between 1 and 7 Myr ago, in agreement with studi...

  7. The Luminosity Function of OB Associations in the Galaxy

    Science.gov (United States)

    McKee, Christopher F.; Williams, Jonathan P.

    1997-02-01

    OB associations ionize the interstellar medium, producing both localized H II regions and diffuse ionized gas. The supernovae resulting from these associations pressurize and stir the interstellar medium. Using Smith, Biermann, & Mezger's compilation of radio H II regions in the Galaxy, and Kennicutt, Edgar, & Hodge's optical study of H II regions in nearby galaxies, we show that the luminosity distribution of giant OB associations in the Galaxy can be fit by a truncated power law of the form \\Nscra(>S)=\\Nscrau[(Su/S)-1], where S is the ionizing photon luminosity, \\Nscra(>S) is the number of associations with a luminosity of at least S, and Su is the upper limit to the distribution. The coefficient \\Nscrau is the number of the most luminous associations, with a luminosity between 0.5Su and Su. For the Galaxy, \\Nscrau=6.1 the fact that the number of the most luminous associations is significantly larger than unity indicates that there is a physical limit to the maximum size of H II regions in the Galaxy. To extend the luminosity distribution to small H II regions, we assume that the birthrate of associations, \\Nscr\\dota(>\\Nscr*), is also a truncated power law, \\Nscr\\dota(>\\Nscr*)~[(\\Nscr*u/\\Nscr*)-1], where \\Nscr* is the number of stars in the association. For large associations, the ionizing luminosity is proportional to the number of stars, S~\\Nscr* for smaller associations, we use both an analytic and a Monte Carlo approach to find the resulting luminosity distribution \\Nscra(>S). H II regions are generally centrally concentrated, with only the dense central regions being bright enough to appear in radio catalogs. Anantharamaiah postulated that radio H II regions have extended envelopes in order to account for diffuse radio recombination line emission in the Galaxy. Some of these envelopes are visible as the ionized ``worms'' discussed by Heiles and coworkers. We estimate that on the average the envelopes of radio H II regions absorb about twice

  8. Study of Eclipsing Binary and Multiple Systems in OB Associations IV: Cas OB6 Member DN Cas

    CERN Document Server

    Bakis, V; Bilir, S; Eker, Z

    2016-01-01

    An early-type, massive, short-period ($P_{\\rm orb}=2^{\\rm d}.310951$) eclipsing spectroscopic binary DN Cas has been re-visited with new spectral and photometric data. The masses and radii of the components have been obtained as $M_1=19.04\\pm0.07 M_\\odot$, $M_2=13.73\\pm 0.05M_\\odot$ and $R_1=7.22\\pm0.06 R_\\odot$, $R_2=5.79\\pm0.06R_\\odot$, respectively. Both components present synchronous rotation ($V_{\\rm rot1}=160\\,$km s$^{-1}$, $V_{\\rm rot2}=130\\,$km s$^{-1}$) with their orbit. Orbital period analysis yielded a physically bound additional component in the system with a minimum mass of $M_3=0.88 M_\\odot$ orbiting in an eccentric orbit ($e=0.37\\pm0.2$) with an orbital period of $P_{12}=42\\pm9$ yrs. High precision absolute parameters of the system allowed us to derive a distance to DN Cas as 1.7$\\pm$0.2 kpc which locates the system within the borders of the Cas OB6 association (d=1.8 kpc; Mel'nik & Dambis, 2009). The space velocities and the age of DN Cas are in agreement with those of Cas OB6. The age of ...

  9. (CH4)-C-14 Measurements in Greenland Ice: Investigating Last Glacial Termination CH4 Sources

    DEFF Research Database (Denmark)

    Petrenko, V. V.; Smith, A. M.; Brook, E. J.;

    2009-01-01

    contributions to this increase. We present measurements of (CH4)-C-14 in glacial ice, targeting this transition, performed by using ice samples obtained from an ablation site in west Greenland. Measured (CH4)-C-14 values were higher than predicted under any scenario. Sample (CH4)-C-14 appears to be elevated by...

  10. Statistical study of OB stars in NGC 6334 and NGC 6357

    Science.gov (United States)

    Russeil, D.; Zavagno, A.; Adami, C.; Anderson, L. D.; Bontemps, S.; Motte, F.; Rodon, J. A.; Schneider, N.; Ilmane, A.; Murphy, K. J.

    2012-02-01

    Context. Star-forming complexes are large structures exhibiting massive star-formation at different stages of evolution, from dense cores to well-developed H ii regions. They are very interesting for the study of the formation and evolution of stars. NGC 6334 and NGC 6357 are two active and relatively nearby star-forming complexes. From the extinction map and the sub-mm cold dust emission, and because they have similar velocities, these regions are most likely connected. However, located in the direction of the Galactic center their radial velocity is not representative of their distance. An alternative is then to determine the distance of NGC 6334 and NGC 6357 from their stellar content. Aims: Our aim is to perform a census of O-B3 ionising stars in NGC 6334 and NGC 6357, to determine the extinction coefficient, and the distance of both regions. A census of O-B3 stars is an essential basis for estimating the statistical lifetime of the earliest massive star-forming phases. Methods: We performed a U, B, V, and R photometric survey of a large area covering NGC 6334 and NGC 6357 with the VIMOS (ESO-VLT) and the MOSAIC (CTIO) instruments. This allows us to have a complete census of O to B3 stars up to V = 22.6 mag. The OB stars are selected based on their U - B and B - V colors. The most robust extinction coefficient is determined from color - color plots before computing the distance of the OB stars. Results: We find a higher value than typical of the diffuse interstellar medium for RV of 3.53 ± 0.08 and 3.56 ± 0.15 for NGC 6357 and NGC 6334, respectively. Adopting these RV values, the distances of NGC 6357 and NGC 6334 are 1.9 ± 0.4 kpc and 1.7 ± 0.3 kpc. We conclude that, within the error bars, both regions are thus at the same distance of 1.75 kpc (weighted mean). We confirm that the value of RV is linked to the large dust grain content. In particular, we found that there are more very small grains in NGC 6357 than in NGC 6334, suggesting that NGC 6357 could

  11. LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice[S

    OpenAIRE

    Archer, Amena; Stolarczyk, Émilie; Doria, Maria Luisa; Helguero, Luisa; Domingues, Rosário; Howard, Jane K; Mode, Agneta; Korach-André, Marion; Gustafsson, Jan-Åke

    2013-01-01

    To investigate the role of liver X receptor (LXR) in adipose tissue metabolism during obesity, ob/ob mice were treated for 5 weeks with the synthetic LXR agonist GW3965. MRI analysis revealed that pharmacological activation of LXR modified fat distribution by decreasing visceral (VS) fat and inversely increasing subcutaneous (SC) fat storage without affecting whole body fat content. This was concordant with opposite regulation by GW3965 of the lipolytic markers hormone-sensitive lipase (HSL) ...

  12. Dropping Probability Reduction in OBS Networks: A Simple Approach

    KAUST Repository

    Elrasad, Amr

    2016-08-01

    In this paper, we propose and derive a slotted-time model for analyzing the burst blocking probability in Optical Burst Switched (OBS) networks. We evaluated the immediate and delayed signaling reservation schemes. The proposed model compares the performance of both just-in-time (JIT) and just-enough-time (JET) signaling protocols associated with of void/non-void filling link scheduling schemes. It also considers none and limited range wavelength conversions scenarios. Our model is distinguished by being adaptable to different offset-time and burst length distributions. We observed that applying a limited range of wavelength conversion, burst blocking probability is reduced by several orders of magnitudes and yields a better burst delivery ratio compared with full wavelength conversion.

  13. The OB association LH 58 in the Large Magellanic Cloud

    Science.gov (United States)

    Garmany, Catharine D.; Massey, Philip; Parker, Joel WM.

    1994-01-01

    We present charge coupled device (CCD) photometry and spectroscopy for stars in Lucke-Hodge 58, an isolated OB association in the Large Magellanic Cloud (LMC) northwest of 30 Doradus. The photometric catalog contains 839 stars with UBV magnitudes complete to V approximately = 19. We have obtained spectra and classified 35 stars; combined with previous published spectral types, we find 22 O-type stars. The earliest type is O3-4 V, and there are three Wolf-Rayet (WR) stars in the association. The slope of the initial mass function, Gamma = -1.7 +/- 0.3, is in good agreement with other LMC associations. The presence of several evolved supergiants with masses about 15-25 solar mass suggests that some star formation took place as early as 10 million years ago, but the majority of stars formed coevally within the past few million years.

  14. 9 cenas, algumas obs-cenas, da rua

    Directory of Open Access Journals (Sweden)

    Robert Moses Pechman

    2009-08-01

    Full Text Available Importa aqui tomar o acontecimento urbano como sintoma da cidade. Mas de que sofre a cidade? De excesso de individualismo e do escasseamento da vida pública na rua. Mas se o que caracteriza a cidade é o acolhimento do Outro, que se desdobra em convivialidades e em sociabilidades, como podemos pensar numa cidade sem que a questão da hospitalidade venha à tona? À propósito dessa contradição entre cidade e individualismo e privativismo e hospitalidade, me ponho a observar nossas ruas e a divisar certas cenas urbanas, depreendendo daí o que essas cenas podem nos contar de um ethos citadino. E, sim, elas nos contam muitas coisas de uma nova paisagem urbana/humana que insiste em desmanchar a imagem do acolhimento como a cena primordial da cidade, impondo sua obscena verdade, sua cena obs-cena.

  15. Augmenting the Stability of OB Dump by Using Fly Ash: A Geo Technical Approach to Sustainably Manage OB Dump at Jharia Coal Field, India

    Directory of Open Access Journals (Sweden)

    Anup Kumar Gupta*

    2016-04-01

    Full Text Available This paper is mainly focused over the possible utilization of fly ash along with OB dump to enhance the stability of OB dump and thus provide a sustainable approach for better waste management of both these materials simultaneously. Instability of coal mine overburden (OB dumps is an important problem in most of the coal mines like Jharia coalfields in India. This is mainly occurring due to sliding nature of the rock material, lack of vegetation etc. Numbers of Environmental and health issues are associated with these unstable OB dumps. As it may easily flow with running water can contaminate the nearby water resource as well as carbonaceous content of the dump causes air pollution due to simultaneous combustion. On the other hand management of coal ash that is produced from thermal plants is also an important task. Dumping of fly ash in open may cause number of environmental problems. Various geotechnical and physical parameters such as particle size analysis, specific gravity, density, and friction angle/cohesion test have been performed to check the stability of OB dump and to analyze impacts of fly ash utilization to stabilize the OB dump.

  16. Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice.

    Directory of Open Access Journals (Sweden)

    Neira Sáinz

    Full Text Available Absence of leptin has been associated with reduced skeletal muscle mass in leptin-deficient ob/ob mice. The aim of our study was to examine the effect of leptin on the catabolic and anabolic pathways regulating muscle mass. Gastrocnemius, extensor digitorum longus and soleus muscle mass as well as fiber size were significantly lower in ob/ob mice compared to wild type littermates, being significantly increased by leptin administration (P<0.001. This effect was associated with an inactivation of the muscle atrophy-related transcription factor forkhead box class O3 (FoxO3a (P<0.05, and with a decrease in the protein expression levels of the E3 ubiquitin-ligases muscle atrophy F-box (MAFbx (P<0.05 and muscle RING finger 1 (MuRF1 (P<0.05. Moreover, leptin increased (P<0.01 protein expression levels of peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha, a regulator of muscle fiber type, and decreased (P<0.05 myostatin protein, a negative regulator of muscle growth. Leptin administration also activated (P<0.01 the regulators of cell cycle progression proliferating cell nuclear antigen (PCNA and cyclin D1, and increased (P<0.01 myofibrillar protein troponin T. The present study provides evidence that leptin treatment may increase muscle mass of ob/ob mice by inhibiting myofibrillar protein degradation as well as enhancing muscle cell proliferation.

  17. MW-OBS: An Improved Pruning Method for Topology Design of Neural Networks

    Institute of Scientific and Technical Information of China (English)

    ZHU Yan; LU Yingrong; LI Qian

    2006-01-01

    Topology design of artificial neural networks (ANNs) is an important problem for large scale applications. This paper describes a new efficient pruning method, the multi-weight optimal brain surgeon (MW-OBS) method, to optimize neural network topologies. The advantages and disadvantages of the OBS and unit-OBS were analyzed to develop the method. Actually, optimized topologies are difficult to get within reasonable times for complex problems. Motivating by the mechanism of natural neurons, the MW-OBS method balances the accuracy and the time complexity to achieve better neural network performance. The method will delete multiple connections among neurons according to the second derivative of the error function, so the arithmetic converges rapidly while the accuracy of the neural network remains high. The stability and generalization ability of the method are illustrated in a Java program. The results show that the MW-OBS method has the same accuracy as OBS, but time is similar to that of unit-OBS. Therefore, the MW-OBS method can be used to efficiently optimize structures of neural networks for large scale applications.

  18. Performance and cost analysis of all-optical switching: OBS and OCS

    Directory of Open Access Journals (Sweden)

    Ekularn Dhavarudha

    2011-08-01

    Full Text Available This paper presents a study of performance and cost analysis of optical circuit switching (OCS and optical burstswitching (OBS by proposing the clear images of their node architectures and cost formulations. Then, we apply servicelevel agreement (SLA of the high quality of service application in the terms of network blocking probability and averagenetwork delay to demonstrate OCS and OBS performances, their investment costs, and network dimensioning methodology.Applying SLA to our studies can illustrate the impact of contention resolution and blocking resolution schemes to theperformances and costs of OBS and OCS, accordingly. The simulations illustrate that OBS applying WC gives the bestperformance among all architectures deploying the same offered bandwidth. The investigations also show that WC is a majortechnique contributing high performance gain to both OCS and OBS. Especially for OBS, WC is an important scheme allowingOBS high data grooming property as its performance gain contributing to OBS is much higher than those of OCS. For thecost analysis, OCS is the most economic among all architectures. BA provides the most cost effectiveness among all OBScontention resolution schemes. Lastly, FDL is the least cost effective scheme as it gives little performance enhancement butadds more cost to the network.

  19. Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lepob/ob mice

    International Nuclear Information System (INIS)

    It has long been a matter of debate whether the hormone-sensitive lipase (HSL)-mediated lipolysis in pancreatic β-cells can affect insulin secretion through the alteration of lipotoxicity. We generated mice lacking both leptin and HSL (Lepob/ob/HSL-/-) and explored the role of HSL in pancreatic β-cells in the setting of obesity. Lepob/ob/HSL-/- developed elevated blood glucose levels and reduced plasma insulin levels compared with Lepob/ob/HSL+/+ in a fed state, while the deficiency of HSL did not affect glucose homeostasis in Lep+/+ background. The deficiency of HSL exacerbated the accumulation of triglycerides in Lepob/ob islets, leading to reduced glucose-stimulated insulin secretion. The deficiency of HSL also diminished the islet mass in Lepob/ob mice due to decreased cell proliferation. In conclusion, HSL affects insulin secretary capacity especially in the setting of obesity.

  20. Microstructural analyses of B{sub 4}C-CeO{sub 2} and B{sub 4}C-La{sub 2}O{sub 3} ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, Tatsuaki, E-mail: sakamoto.tatsuaki@eng.ehime-u.ac.jp [Department of Materials Science and Biotechnology, Ehime University, 3 Bunkyo-cho, Matsuyama 790-8577 (Japan); Sun, Shu-Chen [School of Materials and Metallurgy, Northeastern University, Shenyang 110004 (China); Furuno, Tomoya; Kajioka, Michio [Graduate Student of Ehime Univerisity, 3 Bunkyo-cho, Matsuyama 790-8577 (Japan); Nakai, Kiyomichi [Department of Materials Science and Biotechnology, Ehime University, 3 Bunkyo-cho, Matsuyama 790-8577 (Japan); Kurishita, Hiroaki [International Research Center for Nuclear Materials Science, Institute for Materials Research, Tohoku University, Oarai, Ibaraki 311-1313 (Japan); Kobayashi, Sengo [Department of Materials Science and Biotechnology, Ehime University, 3 Bunkyo-cho, Matsuyama 790-8577 (Japan); Wu, Wen-Yuan; Tu, Gan-Feng [School of Materials and Metallurgy, Northeastern University, Shenyang 110004 (China); Matsuda, Seiji [Department of Anatomy and Embryology, Ehime University, Shizugawa, Toon 791-0295 (Japan)

    2011-10-01

    Effects of additions of CeO{sub 2} and La{sub 2}O{sub 3} on microstructure and mechanical properties of B{sub 4}C fabricated under and without hot press have been investigated. Vickers hardness and fracture strength are increased by hot press due to the reduction of porosity because the sintering rate is enhanced. Hardness is increased by the reduction of porosity because crack probably occurs when the hardness is measured due to pore as an initiation point of crack. Hardness increases with increasing additions of CeO{sub 2} and La{sub 2}O{sub 3} because porosity decreases due to the formation of CeB{sub 6} and LaB{sub 6} on the grain boundary of B{sub 4}C, respectively. The borides are formed through reaction between solid phases, which might induce coherent boundary between boride and B{sub 4}C. Such coherency also contributes to strengthening the grain boundary of B{sub 4}C. The addition of CeO{sub 2} enhances the sintering rate more than that of La{sub 2}O{sub 3}, resulting in higher hardness of B{sub 4}C-CeO{sub 2} than that of B{sub 4}C-La{sub 2}O{sub 3}.

  1. Acquisition of Multicomponent-4C Seismic Data from Unconventional Marine Reservoirs to Improve Exploration and Risk Attenuation in Reservoir Characterization

    Science.gov (United States)

    Aluka, I. J.

    2013-12-01

    The move to explore for commercial oil and gas from unconventional reservoirs such as shale/mudstone and tight gas sand reservoirs is having serious technical challenges. Multicomponent- 4C seismic data acquisition in marine settings will go a long way to assist oil and gas companies to discover unconventional resources with significant commercial value in the marine environments. Multicomponent technology has been proved to be effective in exploration and reservoir characterization and risk reduction. The technology provides enhanced strata images by reflecting independent subsurfaces, direct lithofacies and hydrocarbon indication compared to only conventional P-wave seismic stratigraphy. Multi component seismic data can be acquired in the marine settings by utilizing energy from towed air-gun arrays, and 4-component ocean bottom sensor (4-C OBS) packages deployed on the seafloor. Because the S waves do not travel through liquids, the sensors have to be deployed on the seafloor. The 4-component ocean bottom sensor comprises of a hydrophone, a gimbaled 3-component geophone as opposed to ungimbaled 3-component geophone. This gimbaled 3-component geophone is continually rotated by gravity to make sure that the moving-coil elements are placed in the crossline horizontal, and vertical, inline horizontal directions. Two or more vessels are used in marine multicompnent data acquisition. One vessel is a source vessel and the others are connected to the seafloor cable and record the 4-C seismic data. Every receiver on the seafloor is composed of a single 4-C sensor package, which is stationary during data recording. P-wave data are combination of particle-velocity wavefield recorded by the vertical geophone and pressure wavefield recorded by the hydrophone. The inline and crossline horizontal geophones record the particle-velocity data which are used to generate the upgoing reflected SV wavefield arriving at the seafloor. The downgoing P wavefield at non normal angles of

  2. Globules and pillars in Cygnus X. I. Herschel far-infrared imaging of the Cygnus OB2 environment

    Science.gov (United States)

    Schneider, N.; Bontemps, S.; Motte, F.; Blazere, A.; André, Ph.; Anderson, L. D.; Arzoumanian, D.; Comerón, F.; Didelon, P.; Di Francesco, J.; Duarte-Cabral, A.; Guarcello, M. G.; Hennemann, M.; Hill, T.; Könyves, V.; Marston, A.; Minier, V.; Rygl, K. L. J.; Röllig, M.; Roy, A.; Spinoglio, L.; Tremblin, P.; White, G. J.; Wright, N. J.

    2016-06-01

    The radiative feedback of massive stars on molecular clouds creates pillars, globules and other features at the interface between the H II region and molecular cloud. Optical and near-infrared observations from the ground as well as with the Hubble or Spitzer satellites have revealed numerous examples of such cloud structures. We present here Herschel far-infrared observations between 70 μm and 500 μm of the immediate environment of the rich Cygnus OB2 association, performed within the Herschel imaging survey of OB Young Stellar objects (HOBYS) program. All of the observed irradiated structures were detected based on their appearance at 70 μm, and have been classified as pillars, globules, evaporating gasous globules (EGGs), proplyd-like objects, and condensations. From the 70 μm and 160 μm flux maps, we derive the local far-ultraviolet (FUV) field on the photon dominated surfaces. In parallel, we use a census of the O-stars to estimate the overall FUV-field, that is 103-104 G0 (Habing field) close to the central OB cluster (within 10 pc) and decreases down to a few tens G0, in a distance of 50 pc. From a spectral energy distribution (SED) fit to the four longest Herschel wavelengths, we determine column density and temperature maps and derive masses, volume densities and surface densities for these structures. We find that the morphological classification corresponds to distinct physical properties. Pillars and globules are massive (~500 M⊙) and large (equivalent radius r ~ 0.6 pc) structures, corresponding to what is defined as "clumps" for molecular clouds. EGGs and proplyd-likeobjects are smaller (r ~ 0.1 and 0.2 pc) and less massive (~10 and ~30 M⊙). Cloud condensations are small (~0.1 pc), have an average mass of 35 M⊙, are dense (~6 × 104 cm-3), and can thus be described as molecular cloud "cores". All pillars and globules are oriented toward the Cyg OB2 association center and have the longest estimated photoevaporation lifetimes, a few million

  3. Pressure effect on structural, elastic, and thermodynamic properties of tetragonal B4C4

    International Nuclear Information System (INIS)

    The compressibility, elastic anisotropy, and thermodynamic properties of the recently proposed tetragonal B4C4 (t-B4C4) are investigated under high temperature and high pressure by using of first-principles calculations method. The elastic constants, bulk modulus, shear modulus, Young’s modulus, Vickers hardness, Pugh’s modulus ratio, and Poisson’s ratio for t-B4C4 under various pressures are systematically explored, the obtained results indicate that t-B4C4 is a stiffer material. The elastic anisotropies of t-B4C4 are discussed in detail under pressure from 0 GPa to 100 GPa. The thermodynamic properties of t-B4C4, such as Debye temperature, heat capacity, and thermal expansion coefficient are investigated by the quasi-harmonic Debye model

  4. Pressure effect on structural, elastic, and thermodynamic properties of tetragonal B4C4

    Directory of Open Access Journals (Sweden)

    Baobing Zheng

    2015-03-01

    Full Text Available The compressibility, elastic anisotropy, and thermodynamic properties of the recently proposed tetragonal B4C4 (t-B4C4 are investigated under high temperature and high pressure by using of first-principles calculations method. The elastic constants, bulk modulus, shear modulus, Young’s modulus, Vickers hardness, Pugh’s modulus ratio, and Poisson’s ratio for t-B4C4 under various pressures are systematically explored, the obtained results indicate that t-B4C4 is a stiffer material. The elastic anisotropies of t-B4C4 are discussed in detail under pressure from 0 GPa to 100 GPa. The thermodynamic properties of t-B4C4, such as Debye temperature, heat capacity, and thermal expansion coefficient are investigated by the quasi-harmonic Debye model.

  5. 32 CFR 1630.42 - Class 4-C: Alien or dual national.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Class 4-C: Alien or dual national. 1630.42... CLASSIFICATION RULES § 1630.42 Class 4-C: Alien or dual national. In Class 4-C shall be placed any registrant who... service in the United States. (b) Is an alien and who has departed from the United States prior to...

  6. Constraints on Massive Star Formation: Cygnus OB2 was always an Association

    CERN Document Server

    Wright, Nicholas J; Goodwin, Simon P; Drake, Jeremy J

    2013-01-01

    We examine substructure and mass segregation in the massive OB association Cygnus OB2 to better understand its initial conditions. Using a well understood Chandra X-ray selected sample of young stars we find that Cyg OB2 exhibits considerable physical substructure and has no evidence for mass segregation, both indications that the association is not dynamically evolved. Combined with previous kinematical studies we conclude that Cyg OB2 is dynamically very young, and what we observe now is very close to its initial conditions: Cyg OB2 formed as a highly substructured, unbound association with a low volume density (< 100 stars/pc^3). This is inconsistent with the idea that all stars form in dense, compact clusters. The massive stars in Cyg OB2 show no evidence for having formed particularly close to one another, nor in regions of higher than average density. Since Cyg OB2 contains stars as massive as ~100 Mo this result suggests that very massive stars can be born in relatively low-density environments. Thi...

  7. A WISE Census of Young Stellar Objects in Perseus OB2 Association

    CERN Document Server

    Azimlu, Mohaddesseh; Muench, August A

    2015-01-01

    We have performed a WISE (Wide-Field Infrared Survey Explorer) based study to identify and characterize young stellar objects (YSOs) in 12x12 degree Perseus OB2 association. Spectral energy distribution (SED) slope in range of 3.4-12 micron and a 5sigma selection criteria were used to select our initial sample. Further manual inspection reduced our final catalog to 156 known and 119 YSO candidate. The spatial distribution of newly found YSOs all over the field shows an older generation of star formation which most of its massive members have evolved into main sequence stars. In contrast, the majority of younger members lie within the Perseus molecular cloud and currently active star forming clusters such as NGC1333 and IC348. We also identified additional 66 point sources which passed YSO selection criteria but are likely AGB stars. However their spatial distribution suggests that they may contain a fraction of the YSOs. Comparing our results with the commonly used color-color selections, we found that while ...

  8. La Asociación OB Bochum7 combinando datos IR y ópticos

    Science.gov (United States)

    Corti, M. A.; Bosch, G. L.; Niemela, V. S.

    We present the results of an analysis of IR data in the region of the galactic OB association Bo7, obtained from the archives of the IRAS satellite mission and the 2MASS survey. Bo7 is located at the end of Perseus spiral arm. Distances of possible members of the Bo7 association were determined calculating the absorption from the E(V-K) colour excess. These members had been previously selected according to their UBV colours and spectra. The distance values obtained with IR excess have a smaller error than those obtained considering the E(B-V) excess. An extended interstellar dust cloud (detected in IRAS maps) is found to be probably associated with the members of Bo7. Two IRAS point sources observed in the region have characteristics of star formation sites. One of these point sources has been observed in CS(2-1) by Bronfman et al. (1996), who determined a value of (LSR) velocity of 44 km/s, close to the velocity of stars in Bo7 (Corti et al. 2003). A group of main sequence O - B0.5 stars appear near the location of the aforementioned IRAS point source, suggesting sequential star formation in the Bo7 region.

  9. A photometric variability study of massive stars in Cygnus OB2

    CERN Document Server

    Salas, J; Barbá, R H

    2014-01-01

    We have conducted a 1.5 year-long variability study of the stars in the Cygnus OB2 association, the region in the northern hemisphere with the highest density of optically visible massive stars. The survey was conducted using four pointings in the Johnson $R$ and $I$ bands with a 35 cm Meade LX200-ACF telescope equipped with a 3.2 Mpixel SBIG ST10-XME CCD camera and includes 300+ epochs in each filter. A total of 1425 objects were observed with limiting magnitudes of 15 in $R$ and 14 in $I$. The photometry was calibrated using reference stars with existing $UBVJHK$ photometry. Bright stars have precisions better than 0.01 magnitudes, allowing us to detect 52 confirmed and 19 candidate variables, many of them massive stars without previous detections as variables. Variables are classified as eclipsing, pulsating, irregular/long period, and Be. We derive the phased light curves for the eclipsing binaries, with periods ranging from 1.3 to 8.5 days.

  10. On the observability of bow shocks of Galactic runaway OB stars

    CERN Document Server

    Meyer, D M -A; Kuiper, R; Kley, W

    2016-01-01

    Massive stars that have been ejected from their parent cluster and supersonically sailing away through the interstellar medium (ISM) are classified as exiled. They generate circumstellar bow shock nebulae that can be observed. We present two-dimensional, axisymmetric hydrodynamical simulations of a representative sample of stellar wind bow shocks from Galactic OB stars in an ambient medium of densities ranging from n_ISM=0.01 up to 10.0/cm3. Independently of their location in the Galaxy, we confirm that the infrared is the most appropriated waveband to search for bow shocks from massive stars. Their spectral energy distribution is the convenient tool to analyze them since their emission does not depend on the temporary effects which could affect unstable, thin-shelled bow shocks. Our numerical models of Galactic bow shocks generated by high-mass (~40 Mo) runaway stars yield H$\\alpha$ fluxes which could be observed by facilities such as the SuperCOSMOS H-Alpha Survey. The brightest bow shock nebulae are produc...

  11. No evidence for protoplanetary disk destruction by OB stars in the MYStIX sample

    CERN Document Server

    Richert, Alexander J W; Getman, Konstantin V; Kuhn, Michael A

    2015-01-01

    HST images of proplyds in the Orion Nebula, as well as submillimeter/radio measurements, show that the dominant O7 star Theta1 Ori C photoevaporates nearby disks around pre-main sequence stars. Theory predicts that massive stars photoevaporate disks within distances of order 0.1 pc. These findings suggest that young, OB-dominated massive H II regions are inhospitable to the survival of protoplanetary disks, and subsequently to the formation and evolution of planets. In the current work, we test this hypothesis using large samples of pre-main sequence stars in 20 massive star-forming regions selected with X-ray and infrared photometry in the MYStIX survey. Complete disk destruction would lead to a deficit of cluster members with excess in JHKs and Spitzer/IRAC bands in the vicinity of O stars. In four MYStIX regions containing O stars and a sufficient surface density of disk-bearing sources to reliably test for spatial avoidance, we find no evidence for the depletion of inner disks around pre-main sequence sta...

  12. A Novel Congestion Detection Scheme in TCP Over OBS Networks

    KAUST Repository

    Shihada, Basem

    2009-02-01

    This paper introduces a novel congestion detection scheme for high-bandwidth TCP flows over optical burst switching (OBS) networks, called statistical additive increase multiplicative decrease (SAIMD). SAIMD maintains and analyzes a number of previous round-trip time (RTTs) at the TCP senders in order to identify the confidence with which a packet loss event is due to network congestion. The confidence is derived by positioning short-term RTT in the spectrum of long-term historical RTTs. The derived confidence corresponding to the packet loss is then taken in the developed policy for TCP congestion window adjustment. We will show through extensive simulation that the proposed scheme can effectively solve the false congestion detection problem and significantly outperform the conventional TCP counterparts without losing fairness. The advantages gained in our scheme are at the expense of introducing more overhead in the SAIMD TCP senders. Based on the proposed congestion control algorithm, a throughput model is formulated, and is further verified by simulation results.

  13. The interstellar medium towards the Ara OB1 region

    CERN Document Server

    Henderson, Christopher D; Hearnshaw, John B

    2008-01-01

    We present high resolution (R ~ 4 km/s) absorption measurements of the interstellar NaI and CaII lines measured towards 14 early-type stars of distance 123 pc - 1650 pc, located in the direction of the Ara OB1 stellar cluster. The line profiles can broadly be split into four distinct groupings of absorption component velocity, and we have attempted to identify an origin and distance to each of these interstellar features. For gas with absorption covering the velocity range -10 km/s < V_helio < +10 km/s, we can identify the absorbing medium with local gas belonging to the Lupus-Norma interstellar cavity located between 100 and 485 pc in this galactic direction. Gas with velocities spanning the range -20 km/s < V_helio < +20 km/s is detected towards stars with distances of 570-800 pc. We identify a wide-spread interstellar feature at V_helio ~ -15 km/s with the expanding HI shell called GSH 337+00-05, which is now placed at a distance of ~530 pc.

  14. Debris Disks in the Upper Scorpius OB Association

    CERN Document Server

    Carpenter, John M; Hillenbrand, Lynne A; Meyer, Michael R

    2009-01-01

    We present MIPS 24um and 70um photometry for 205 members of the Upper Scorpius OB Association. These data are combined with published MIPS photometry for 15 additional association members to assess the frequency of circumstellar disks around 5 Myr old stars with spectral types between B0 and M5. Twelve stars have a detectable 70um excess, each of which also has a detectable 24um excess. A total of 54 stars are identified with a 24um excess more than 32% above the stellar photosphere. The MIPS observations reveal 19 excess sources -- 8 A/F/G stars and 11 K/M stars -- that were not previously identified with an 8um or 16um excess. The lack of short-wavelength emission and the weak 24um excess suggests that these sources are debris systems or the remnants of optically thick primordial disks with inner holes. Despite the wide range of luminosities of the stars hosting apparent debris systems, the excess characteristics are consistent with all stars having dust at similar orbital radii after factoring in variation...

  15. D Recording of a 19-CENTURY OB River Ship

    Science.gov (United States)

    Pushkarev, A. A.; Zaytceva, O. V.; Vavulin, M. V.; Skorobogatova, A. Y.

    2016-06-01

    A 3D recording of a 19-century wooden ship discovered on the bank of the river Ob (Western Siberia) was performed in autumn 2015. The archaeologized ship was partly under water, partly lying ashore, buried under fluvial deposits. The 3D recording was performed in October, when the water level was at its lowest after clearing the area around the ship. A 3D recording at the place of discovery was required as part of the ship museumification and reconstruction project. The works performed were primarily aimed at preserving as much information about the object as possible. Given the location and peculiar features of the object, a combination of close-range photogrammetry and aerial photography was considered to be the best possible solution for creating a high-quality 3D model. The dismantled ship was delivered to Nizhnevartovsk Museum of Local History in October 2015. The ship is going to be reassembled using the created 3D model to be exhibited in the museum. The resulting models are also going to be used to make a virtual 3D reconstruction of the ship in the future. We shot a stereoscopic video for Nizhnevartovsk Museum of Local History to let visitors see the place of discovery and explore the ship in greater details. Besides, 3D printing allowed for creating a miniature of the ship, which is also going to be included in the exposition devoted to this unique discovery.

  16. Ensuring QOS Guarantees in a Hybrid OCS/OBS Network

    CERN Document Server

    S, Sunish Kumar O

    2012-01-01

    The bursting aggregation assembly in edge nodes is one of the key technologies in OBS (Optical Burst Switching) network, which has a direct impact on flow characteristics and packet loss rate. An optical burst assembly technique supporting QoS is presented through this paper, which can automatically adjust the threshold along with the increasing and decreasing volume of business, reduce the operational burst, and generate corresponding BDP (Burst Data Packet) and BCP (Burst Control Packet). In addition to the burst aggregation technique a packet recovery technique by restoration method is also described. The data packet loss due to the physical optical link failure is not currently included in the QoS descriptions. This link failure is also a severe problem which reduces the data throughput of the transmitter node. A mechanism for data recovery from this link failure is vital for guaranteeing the QoS demanded by each user. So this paper will also discusses a specific protocol for reducing the packet loss by u...

  17. Determination of the Galactic Rotation Curve from OB Stars

    CERN Document Server

    Bobylev, V V

    2015-01-01

    We consider three samples of O- and B-type stars from the solar neighborhood 0.6--4 kpc for which we have taken the distances, line-of-sight velocities, and proper motions from published sources. The first sample contains 120 massive spectroscopic binaries. O stars with spectroscopic distances from Patriarchi et al. constitute the second sample. The third sample consists of 168 OB3 stars whose distances have been determined from interstellar calcium lines. The angular velocity of Galactic rotation at the solar distance $\\Omega_0,$ its two derivatives $\\Omega'_0$ and $\\Omega"_0,$ and the peculiar velocity components of the Sun $(U,V,W)_\\odot$ are shown to be well determined from all three samples of stars. They are determined with the smallest errors from the sample of spectroscopic binary stars and the sample of stars with the calcium distance scale. The fine structure of the velocity field associated with the influence of the Galactic spiral density wave clearly manifests itself in the radial velocities of s...

  18. 3D RECORDING OF A 19-CENTURY OB RIVER SHIP

    Directory of Open Access Journals (Sweden)

    A. A. Pushkarev

    2016-06-01

    Full Text Available A 3D recording of a 19-century wooden ship discovered on the bank of the river Ob (Western Siberia was performed in autumn 2015. The archaeologized ship was partly under water, partly lying ashore, buried under fluvial deposits. The 3D recording was performed in October, when the water level was at its lowest after clearing the area around the ship. A 3D recording at the place of discovery was required as part of the ship museumification and reconstruction project. The works performed were primarily aimed at preserving as much information about the object as possible. Given the location and peculiar features of the object, a combination of close-range photogrammetry and aerial photography was considered to be the best possible solution for creating a high-quality 3D model. The dismantled ship was delivered to Nizhnevartovsk Museum of Local History in October 2015. The ship is going to be reassembled using the created 3D model to be exhibited in the museum. The resulting models are also going to be used to make a virtual 3D reconstruction of the ship in the future. We shot a stereoscopic video for Nizhnevartovsk Museum of Local History to let visitors see the place of discovery and explore the ship in greater details. Besides, 3D printing allowed for creating a miniature of the ship, which is also going to be included in the exposition devoted to this unique discovery.

  19. Near-IR Field Variable Stars in Cygnus OB7

    CERN Document Server

    Wolk, Scott J; Aspin, Colin A

    2013-01-01

    We present a subset of the results of a three season, 124 night, near-infrared monitoring campaign of the dark clouds Lynds 1003 and Lynds 1004 in the Cygnus OB7 star forming region. In this paper, we focus on the field star population. Using three seasons of UKIRT J, H and K band observations spanning 1.5 years, we obtained high-quality photometry on 9,200 stars down to J=17 mag, with photometric uncertainty better than 0.04 mag. After excluding known disk bearing stars we identify 149 variables - 1.6% of the sample. Of these, about 60 are strictly periodic, with periods predominantly < 2 days. We conclude this group is dominated by eclipsing binaries. A few stars have long period signals of between 20 and 60 days. About 25 stars have weak modulated signals, but it was not clear if these were periodic. Some of the stars in this group may be diskless young stellar objects with relatively large variability due to cool star spots. The remaining ~60 stars showed variations which appear to be purely stochastic...

  20. Comparison of nanostructured Al/B4C composite produced by ARB and Al/B4C composite produced by RRB process

    International Nuclear Information System (INIS)

    Research highlights: → The SEM microstructures revealed the well distributed B4C particles in the aluminum matrix for both the composites. → The TEM analysis showed the nanostructured Al/B4C composite was produced by the ARB process successfully. → The ductility (elongation) of the RRB processed composite is higher than that of the ARB processed composite. → The microhardness of the ARB processed composite is higher than that of the RRB processed composite. - Abstract: In the present study, Al/B4C composites were produced and compared in the form of sheets, through accumulative roll bonding (ARB) and repeated roll bonding (RRB) processes. The microstructure of the composites fabricated by both the methods, revealed by scanning electron microscopy (SEM), showed the B4C particles properly distributed in the aluminum matrix. The average grain size of the ARB processed composite was about 186 nm by linear intercept method, based on transmission electron microscopy (TEM) observations. Mechanical properties of the Al/B4C composites produced by two methods were investigated by tensile and hardness tests. The results showed that the tensile strength and hardness of the ARB and RRB processed composites increase with the number of cycles. However, the tensile strength and hardness of the ARB processed composite are much higher than those of the RRB processed composite. The tensile test results revealed that the elongation of the ARB processed composite is lower than that of the RRB processed composite.

  1. Impairment-aware QoS provisioning in dual-header OBS networks

    Institute of Scientific and Technical Information of China (English)

    Yuqi Fan; Bin Wang; Lian Li

    2011-01-01

    Signal degradation due to physical impairments may result in unacceptable bit-error rates of received signals at the destination.Based on earlier work,we study the impairment-aware quality of service(QoS)provisioning problem in dual-header optical burst switching(OBS) networks that employ two control packets for each data burst.At an OBS node,the proposed algorithm schedule bursts for transmission by searching for available resources using admission control and preemption.The algorithm also verifies signal quality.Simulation results show that this algorithm is effective in providing QoS support in OBS networks while considering physical impairment effects.

  2. COSMIC ORIGINS SPECTROGRAPH OBSERVATIONS OF TRANSLUCENT CLOUDS: Cyg OB2 8A

    International Nuclear Information System (INIS)

    Data from the Cosmic Origins Spectrograph (COS) are presented for the first highly reddened target (Cyg OB2 8A) under the COS Science Team's guaranteed time allocation. Column densities of ionic, atomic, and molecular species are reported and implications are discussed. Data from Cyg OB2 8A demonstrate the ability to analyze highly reddened interstellar sight lines with the COS that were unavailable to previous UV instruments. Measured column densities indicate that the Cyg OB2 8A line of sight contains multiple diffuse clouds rather than a dominant translucent cloud.

  3. Expression of the P2X2 receptor in different classes of ileum myenteric neurons in the female obese ob/ob mouse

    Institute of Scientific and Technical Information of China (English)

    Márcia Sanae Mizuno; Amanda Rabello Crisma; Primavera Borelli; Patricia Castelucci

    2012-01-01

    AIM:To examine whether the ob/ob mouse model of obesity is accompanied by enteric nervous system abnormalities such as altered motility.METHODS:The study examined the distribution of the P2X2 receptor (P2X2R) in myenteric neurons of female ob/ob mice.Specifically,we used immunohistochemistry to analyze the co-expression of the P2X2R with neuronal nitric oxide synthase (nNOS),choline acetyltransferase (ChAT),and calretinin (CalR) in neurons of the small intestine myenteric plexus in ob/ob and control female mice.In these sections,we used scanning confocal microscopy to analyze the co-localization of these markers as well as the neuronal density (cm2) and area profile (μm2) of P2X2R-positive neurons.In addition,enteric neurons were labeled using the nicotinamide adenine dinucleotide (NADH) diaphorase method and analyzed with light microscopy as an alternate means by which to analyze neuronal density and area.RESULTS:In the present study,we observed a 29.6% increase in the body weight of the ob/ob animals (OG)compared to the control group (CG).In addition,the average small intestine area was increased by approximately 29.6% in the OG compared to the CG.Immunoreactivity (IR) for the P2X2R,nNOS,ChAT and CalR was detectable in the myenteric plexus,as well as in the smooth muscle,in both groups.This IR appeared to be mainly cytoplasmic and was also associated with the cell membrane of the myenteric plexus neurons,where it outlined the neuronal cell bodies and their processes.P2X2R-IR was observed to co-localize 100% with that for nNOS,ChAT and CalR in neurons of both groups.In the ob/ob group,however,we observed that the neuronal density (neuron/cm2) of P2X2R-IR cells was increased by 62% compared to CG,while that of NOS-IR and ChAT-IR neurons was reduced by 49% and 57%,respectively,compared to control mice.The neuronal density of CalR-IR neurons was not different between the groups.Morphometric studies further demonstrated that the cell body profile area (

  4. THE INITIAL MASS FUNCTION OF FIELD OB STARS IN THE SMALL MAGELLANIC CLOUD

    International Nuclear Information System (INIS)

    Some theories of star formation suggest massive stars may only form in clustered environments, which would create a deficit of massive stars in low-density environments. Observationally, Massey finds such a deficit in samples of the field population in the Small and Large Magellanic Clouds, with an initial mass function (IMF) slope of ΓIMF ∼ 4. These IMF measurements represent some of the largest known deviations from the standard Salpeter IMF slope of ΓIMF = 1.35. Here, we carry out a comprehensive investigation of the mass function above 20 M ☉ for the entire field population of the Small Magellanic Cloud (SMC), based on data from the Runaways and Isolated O Type Star Spectroscopic Survey of the SMC (RIOTS4). This is a spatially complete census of the entire field OB star population of the SMC obtained with the IMACS multi-object spectrograph and MIKE echelle spectrograph on the Magellan telescopes. Based on Monte Carlo simulations of the evolved present-day mass function, we find the slope of the field IMF above 20 M ☉ is ΓIMF = 2.3 ± 0.4. We extend our IMF measurement to lower masses using BV photometry from the OGLE II survey. We use a statistical approach to generate a probability distribution for the mass of each star from the OGLE photometry, and we again find ΓIMF = 2.3 ± 0.6 for stellar masses from 7 M ☉ to 20 M ☉. The discovery and removal of ten runaways in our RIOTS4 sample steepens the field IMF slope to ΓIMF = 2.8 ± 0.5. We discuss the possible effects of binarity and star formation history on our results, and conclude that the steep field massive star IMF is most likely a real effect.

  5. 某医院护士专业自我概念与职业倦怠和离职意愿的相关性调查%A survey on thecorrelation of nurses professional self-concept on j ob burnout and turnover intention in a hospital

    Institute of Scientific and Technical Information of China (English)

    白琼

    2016-01-01

    目的探讨护士的专业自我概念对护士职业倦怠、离职意愿的影响。方法2014年10月,选取某医院护士492名,采用专业自我概念量表、职业倦怠问卷量表和离职意愿量表进行匿名问卷调查。结果护士中出现职业倦怠的比例高达77.64%,职业倦怠护士在情感耗竭(27.15±7.18)、去人格化(9.32±4.07)、职业效能(18.76±7.61)3个维度方面与无职业倦怠护士对比差异有统计学意义(P<0.05),且护士的护龄越长、学历越高、加班时间越久,职业倦怠情况越严重(P<0.05)。护士中具有离职意愿的比例达80%,且离职意愿随着学历、加班时间呈上升趋势(P<0.05),随着护龄呈下降趋势(P<0.05)。具有职业倦怠和离职意愿的护士的专业自我概念与无职业倦怠、无离职意愿比较,差异有统计学意义(P<0.05)。结论护士的专业自我概念与职业倦怠、离职意愿均呈高度相关,可对护士的职业倦怠、离职意愿采取针对性的干预措施,增强护士的专业自我评分。%Objective To explore the impact of nurses�professional self-concept on occupational burnout and turnover intention.Methods 492 nurses were chosen in a hospital in October 2014,and anonymous questionnaire survey of the nurses� professional self-concept,job burnout and turnover intention were conducted.Results The prevalence of the job burnout among the nurses were 77.64% and the score of the emotional exhaustion(27.15±7.18),depersonalization(9.32±4.07)and professional efficacy(18.76±7.61) in 3 articles of job burnout questionnaire were significantly worse than the score of nurse with no job burnout (P<0.05).The longer of working year and working overtime,the higher educational attainment,the more serious situation of the job burnout(P<0.05).The will of turnover in the nurses was almost 80%,and increased with higher educational attainment and longer working overtime were (P<0.05),while declined with longer

  6. Synthesis and Electrochemical Properties of LiFePO4/C for Lithium Ion Batteries.

    Science.gov (United States)

    Gao, Hong; Wang, Jiazhao; Yin, Shengyu; Zheng, Hao; Wang, Shengfu; Feng, Chuanqi; Wang, Shiquan

    2015-03-01

    LiFePO4/C was prepared through a facile rheological phase reaction method by using Fe3(PO4)2, Li3PO4 · 8H2O, and glucose as reactants. The LiFePO4/C samples were characterized by X-ray diffraction, scanning electron microscopy, and thermogravimetric analysis. The electrochemical properties of the samples were investigated. The results show that the LiFePO4/C samples have single-phase olivine-type structure, and their particles feature a spherical shape. The carbon coating on the particles of LiFePO4 is about 1.8% of the LiFePO4/C by weight. The particle size was distributed from 0.2 to 1 µm. The initial discharge capacity of LiFePO4/C reached 154 mA h/g at 0.1 C. The retained discharge capacity of LiFePO4/C was 152.9 mA h g(-1) after 50 cycles. The LiFePO4/C also showed better cycling performance than that of the bare LiPeO4 at a higher charge/discharge rate (1 C). The LIFePO4/C prepared in this way could be a promising cathode material for lithium ion battery application. PMID:26413648

  7. Microstructures and mechanical properties in B{sub 4}C-CeO{sub 2} ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Sun Shuchen, E-mail: sunsc@smm.neu.edu.cn [School of Materials and Metallurgy, Northeastern University, Shenyang 110004 (China); Sakamoto, Tatsuaki; Nakai, Kiyomichi [Department of Materials Science and Biotechnology, Ehime University, 3Bunkyo-cho, Matsuyama 790-8577 (Japan); Kurishita, Hiroaki [International Research Center for Nuclear Materials Science, Institute for Materials Research, Tohoku University, Oarai, Ibaraki 311-1313 (Japan); Kobayashi, Sengo [Department of Materials Science and Biotechnology, Ehime University, 3Bunkyo-cho, Matsuyama 790-8577 (Japan); Xu Jingyu; Cao Hui; Gao Bo; Bianxue; Wu Wenyuan; Tu Ganfeng [School of Materials and Metallurgy, Northeastern University, Shenyang 110004 (China); Matsuda, Seiji [Department of Anatomy and Embryology, Ehime University, Shizugawa, Toon 791-0295 (Japan)

    2011-10-01

    B{sub 4}C-CeO{sub 2} composite ceramics with various concentrations of CeO{sub 2} were fabricated by hot press. The effects of CeO{sub 2} on the microstructures and mechanical properties of the B{sub 4}C-CeO{sub 2} ceramics have been investigated. During hot press, CeB{sub 6} was formed by the reaction between CeO{sub 2} and B{sub 4}C. The B{sub 4}C-CeO{sub 2} ceramics had higher levels of density, fracture toughness, flexural strength and Vickers hardness than those in monolithic B{sub 4}C. The microstructures of the B{sub 4}C-CeO{sub 2} ceramics were observed and analyzed by transmission electron microscopy. In-situ synthesized CeB{sub 6} indicated whisker-like shape and grew along the interface with B{sub 4}C, and different boron carbides with different content of C existed at/around the interface of CeB{sub 6} with B{sub 4}C in the composite ceramics. It made mechanical properties greatly improved.

  8. Synthesis and characterisation of substrate-based peptides as inhibitors of histone demethylase KDM4C

    DEFF Research Database (Denmark)

    Nielsen, Simon D; Leurs, Ulrike; Bergner, Magnus;

    2016-01-01

    The design and synthesis of modified pentapeptides based on a truncated version of the substrate for KDM4C, a histone lysine demethylase (KDM), and investigation of their inhibitory activity at KDM4C is reported. By modifying the lysine residue corresponding to lysine 9 at histone 3 (H3K9), three...

  9. Comparative Precise Parameters for OB Stars in Three Galaxies

    Science.gov (United States)

    Walborn, Nolan

    2014-10-01

    The chemical abundances, wind terminal velocities, and mass-loss rates of OB stars in the Small and Large Magellanic Clouds will be determined homogeneously from high-resolution spectroscopic data in the Mikulski Archive; and they will be further compared with analogous determinations in the Solar Neighborhood. As is well known, the three systems offer a metallicity sequence with values in solar units generally given as 0.2, 0.5, and 1, respectively, which should have corresponding effects on the metallic-line-driven winds. However, the quantitative basis for that general result can and should be improved for various reasons. For instance, it is based on heterogeneous analyses, some dated, of data with varying quality. Moreover, there is not a single metallicity but different relative values for different elements, seldom available for individual stars, with CNO significantly affected by internal evolutionary processes. We propose advances with state-of-the-art analyses of the best data, primarily from STIS and COS in the UV, but also incorporating FUSE observations of the same stars, and IUE high-resolution of a few. We shall also analyze correlative groundbased optical data. J-CB and collaborators have already published recent results for Galactic supergiants and SMC dwarfs, while work on the SMC giants/supergiants is in progress. We shall build upon that work with further Galactic and SMC data, and especially with the still relatively small but significant LMC UV sample, with detailed spectral-type matching insofar as possible. We shall also produce an atlas of all spectra analyzed, to be placed in the Archive as a high-level product to guide future work.

  10. A Theory and Typology of Possession in Ob-Yenissei Languages

    OpenAIRE

    Potanina, Olga Sergeevna; Filchenko, Andrey Yurievich

    2015-01-01

    The paper outlines the on-going study of possession in Ob-Yenissei languages. The languages of the project represent the endangered indigenous idioms belonging to diverse language families and united in the study by their areal affiliation with the posited linguistic area delimited by Ob and Yenissei river basins in Western Siberia. The analysis stems from extended original and legacy fieldwork data, and addresses the key morphosyntactic and semantic features of possession within a contempora...

  11. Kolesarjenje na območju Mestne občine Ptuj

    OpenAIRE

    Cajnko, Uroš

    2012-01-01

    Diplomsko delo obravnava kolesarjenje v Mestni občini Ptuj. Najprej so v uvodnem poglavju predstavljene prednosti kolesarjenja s poudarkom na okoljskem vidiku. V nadaljevanju je predstavljen kolesarski promet v Republiki Sloveniji ter njegova navezava na kolesarske poti v Mestni občini Ptuj. Predstavljene so tudi smernice razvoja kolesarskega omrežja. Prav tako so predstavljene najnovejše ureditve kolesarskega prometa iz tujine, njihovi izvedeni ukrepi in predstavljeni rezultati, na podlagi k...

  12. Performance and cost analysis of all-optical switching: OBS and OCS

    OpenAIRE

    Ekularn Dhavarudha; Chalie Charoenlarpnopparut; Suwan Runggeratigul

    2011-01-01

    This paper presents a study of performance and cost analysis of optical circuit switching (OCS) and optical burstswitching (OBS) by proposing the clear images of their node architectures and cost formulations. Then, we apply servicelevel agreement (SLA) of the high quality of service application in the terms of network blocking probability and averagenetwork delay to demonstrate OCS and OBS performances, their investment costs, and network dimensioning methodology.Applying SLA to our studies ...

  13. Comparative Study on the Marketing Theories of 4P and 4C%4P 与4C 营销理论的比较研究

    Institute of Scientific and Technical Information of China (English)

    尹坤; 李欣

    2015-01-01

    The marketing theories of 4P and 4C can’t be replaced by each other from the perspectives of the theories and the application related with the origination and development of marketing mix.They are origi-nated in different marketing environment and are not contradicted in essence.Hence,it is claimed that the theories of 4P and 4C should be mixed in application according to the industry peculiarities,market compe-tition condition and the different stages of the products.%从营销组合的产生与发展以及理论和应用层面分析认为,4P 和4C 营销理论之间不存在谁取代谁的关系,它们产生于不同的营销环境,没有本质的矛盾。在此基础上提出应该根据具体的行业特征、市场竞争状况和产品所处的不同的生命周期阶段来对4P 和4C 进行组合运用。

  14. 胆汁酸核受体激动剂对瘦素及OB-Rb的影响%Effects of FXR agonist on leptin and OB-Rb

    Institute of Scientific and Technical Information of China (English)

    辛小敏; 张珊珊; 钟慕晓; 杨公利; 彭瑶; 朱薇; 张亚历

    2014-01-01

    目的:观察胆汁酸核受体激动剂GW4064对3T3-L1前脂肪细胞分化过程中瘦素及长型瘦素受体(OB-Rb)和对HepG2细胞 OB-Rb 的影响。方法:用 GW4064干预3T3-L1前脂肪细胞的分化过程,采用荧光real-time PCR 法检测分化过程中第0、2、4、6、8天瘦素及OB-Rb mRNA 相对表达量及ELISA 法检测瘦素分泌情况,同时,用 GW4064干预饥饿后的 HepG2细胞0、12、24、48 h 后,荧光 real-time PCR 法检测 OB-Rb mRNA 相对表达量。结果:GW4064干预后,3T3-L1前脂肪细胞中瘦素 mRNA 相对表达量较对照组明显上升,瘦素蛋白分泌情况与其 mRNA 表达相似,差异均有统计学意义(均 P<0.05),而 OB-Rb mRNA 表达无明显改变(P>0.05);同时,HepG2细胞的OB-Rb mRNA 在干预后表达明显增加,差异有统计学意义(P<0.001)。结论:GW4064可上调脂肪细胞瘦素和HepG2细胞OB-Rb 的表达,目前瘦素在非酒精性脂肪性肝病中的作用及机制尚不明确,而 OB-Rb 的低表达则与非酒精性脂肪性肝病中的瘦素抵抗相关,因此,我们推测胆汁酸核受体激动剂可通过提高肝脏OB-Rb 的表达改善瘦素抵抗,从而达到治疗非酒精性脂肪性肝病的目的。%Objective To investigate the effects of GW4064,one FXR agonist,on the leptin and OB-Rb during the differentiation of 3T3-L1 preadipocytes and on the OB-Rb in the HepG2 cells. Methods The mRNA relative expression of leptin , OB-Rb and the protein of leptin on the day of 0 , 2 , 4 , 6 , 8 during the differentiation of 3T3-L1 preadipocytes after interfered with GW4064 were detected by fluorescent real-time PCR and ELISA , respectively. Meanwhile , the mRNA relative expression of OB-Rb of HepG2 cells after treated with GW4064 0 h , 12 h,24 h,48 h were also examined. Results The mRNA relative expression of leptin in the 3T3-L1 preadipocytes and OB-Rb in the HepG2 cells after treated with GW4064 were significantly

  15. A Catalog of New Spectroscopically Confirmed Massive OB Stars in Carina

    CERN Document Server

    Alexander, Michael J; Povich, Matthew S; McSwain, M Virginia

    2016-01-01

    The Carina star-forming region is one of the largest in the Galaxy, and its massive star population is still being unveiled. The large number of stars combined with high, and highly variable, interstellar extinction makes it inherently difficult to find OB stars in this type of young region. We present the results of a spectroscopic campaign to study the massive star population of the Carina Nebula, with the primary goal to confirm or reject previously identified Carina OB star candidates. A total of 141 known O- and B-type stars and 94 candidates were observed, of which 73 candidates had a high enough signal-to-noise ratio to classify. We find 23 new OB stars within the Carina Nebula, a 32% confirmation rate. One of the new OB stars has blended spectra and is suspected to be a double-lined spectroscopic binary (SB2). We also reclassify the spectral types of the known OB stars and discover nine new SB2s among this population. Finally, we discuss the spatial distribution of these new OB stars relative to known...

  16. Fabrication and Characterization of AL-AL4C3 Nanocomposite by Mechanical Alloying

    Science.gov (United States)

    Mohammad Sharifi, E.; Enayati, M. H.; Karimzadeh, F.

    Aluminum carbide (Al4C3) seems to be an ideal reinforcement for producing aluminum matrix composites. Al4C3 has high hardness and shear strength as well as a high melting point. The dispersion of Al4C3 particles in the matrix produces a pinning effect that reduces aluminum grain growth, which improves the mechanical properties. In this study, aluminum powders were mixed with 4.5 wt.% graphite and mechanically alloyed using a high-energy ball mill in order to produce Al-Al4C3 nanocomposite. The structural evaluation of powder particles after different milling times was studied by X-ray diffractometry, scanning electron microscopy and microhardness measurements. The aluminum crystallite size estimated with broadening of XRD peaks by Williamson-Hall formula. XRD results suggested that the grain size of aluminum decreased to nanometer range (30 nm) during ball milling. No Al4C3 formed during the mechanical alloying process. Milled powders were then annealed at 300-600 °C for 1 h under argon atmosphere. Annealing at temperatures higher than 300 °C led to formation of Al4C3 phase which increased as annealing temperature increased. Aluminum grain size remained in nanometer range after annealing process. The microhardness of powder particles increased after annealing. Both effects are due to the formation of nanosized Al4C3 particles.

  17. CHMP4C Disruption Sensitizes the Human Lung Cancer Cells to Irradiation

    Directory of Open Access Journals (Sweden)

    Kang Li

    2015-12-01

    Full Text Available Human lung cancer is highly invasive and the most malignant among human tumors. Adenocarcinoma as a specific type of non-small cell lung cancer occurs with high frequency and is also highly resistant to radiation therapy. Thus, how to avoid radiation resistance and improve radiotherapy effectiveness is a crucial question. In the present study, human lung cancer A549 and H1299 cells were irradiated using γ-rays from a Co60 irradiator. Protein expression was detected by Western blotting. Cell cycle and apoptosis were measured by flow cytometry. Surviving fraction was determined by colony formation assay. γH2AX and 53BP1 foci formation were examined by fluorescence microscopy. In the results, we show that CHMP4C, a subunit of Endosomal sorting complex-III (ESCRT-III, is involved in radiation-induced cellular response. Radiation-induced Aurora B expression enhances CHMP4C phosphorylation in non-small cell lung cancer (NSCLC cells, maintaining cell cycle check-point and cellular viability as well as resisting apoptosis. CHMP4C depletion enhances cellular sensitivity to radiation, delays S-phase of cell cycle and reduces ionizing radiation (IR-induced γH2AX foci formation. We found that Aurora B targets CHMP4C and inhibition of Aurora B exhibits similar effects with silencing of CHMP4C in radioresistance. We also confirm that CHMP4C phosphorylation is elevated after IR both in p53-positive and-negative cells, indicating that the close correlation between CHMP4C and Aurora B signaling pathway in mediating radiation resistance is not p53 dependent. Together, our work establishes a new function of CHMP4C in radiation resistance, which will offer a potential strategy for non-small cell lung cancer by disrupting CHMP4C.

  18. CHMP4C Disruption Sensitizes the Human Lung Cancer Cells to Irradiation.

    Science.gov (United States)

    Li, Kang; Liu, Jianxiang; Tian, Mei; Gao, Gang; Qi, Xuesong; Pan, Yan; Ruan, Jianlei; Liu, Chunxu; Su, Xu

    2016-01-01

    Human lung cancer is highly invasive and the most malignant among human tumors. Adenocarcinoma as a specific type of non-small cell lung cancer occurs with high frequency and is also highly resistant to radiation therapy. Thus, how to avoid radiation resistance and improve radiotherapy effectiveness is a crucial question. In the present study, human lung cancer A549 and H1299 cells were irradiated using γ-rays from a Co60 irradiator. Protein expression was detected by Western blotting. Cell cycle and apoptosis were measured by flow cytometry. Surviving fraction was determined by colony formation assay. γH2AX and 53BP1 foci formation were examined by fluorescence microscopy. In the results, we show that CHMP4C, a subunit of Endosomal sorting complex-III (ESCRT-III), is involved in radiation-induced cellular response. Radiation-induced Aurora B expression enhances CHMP4C phosphorylation in non-small cell lung cancer (NSCLC) cells, maintaining cell cycle check-point and cellular viability as well as resisting apoptosis. CHMP4C depletion enhances cellular sensitivity to radiation, delays S-phase of cell cycle and reduces ionizing radiation (IR)-induced γH2AX foci formation. We found that Aurora B targets CHMP4C and inhibition of Aurora B exhibits similar effects with silencing of CHMP4C in radioresistance. We also confirm that CHMP4C phosphorylation is elevated after IR both in p53-positive and-negative cells, indicating that the close correlation between CHMP4C and Aurora B signaling pathway in mediating radiation resistance is not p53 dependent. Together, our work establishes a new function of CHMP4C in radiation resistance, which will offer a potential strategy for non-small cell lung cancer by disrupting CHMP4C. PMID:26712741

  19. Evaulation of B{sub 4}C as an ablator material for NIF capsules. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Burnham, A.K.; Alford, C.S.; Makowiecki, D.M.; Dittrich, T.R.; Wallace, R.J.; Honea, E.C.; King, C.M. [Lawrence Livermore National Lab., CA (United States); Steinman, D. [General Atomics, San Diego, CA (United States)

    1997-03-26

    Boron carbide (B{sub 4}C) is examined as a potential fuel container and ablator for implosion capsules on the National Ignition Facility (NIF). A capsule of pure B{sub 4}C encasing a layer of solid DT implodes stably and ignites with anticipated NIF x-ray drives, producing 18 MJ of energy. Thin films of B{sub 4}C were found to be resistant to oxidation and modestly transmitting in the infrared (IR), possibly enabling IR fuel characterization and enhancement for thin permeation barriers but not for full-thickness capsules. Polystyrene mandrels 0.5 mm in diameter were successfully coated with 0.15-2.0 micrometers of B{sub 4}C. Thickness estimated from optical density agreed well with those measured by scanning electron microscopy (SEM). The B{sub 4}C microstructure was columnar but finer than for Be made at the same conditions. B{sub 4}C is a very strong material, with a fiber tensile strength capable of holding NIF fill pressures at room temperature, but it is also very brittle, and microscopic flaws or grain structure may limit the noncryogenic fill pressure. Argon (Ar) permeation rates were measured for a few capsules that had been further coated with 5 micrometers of plasma polymer. The B{sub 4}C coatings tended to crack under tensile load. Some shells filled more slowly than they leaked, suggesting that the cracks open and close under opposite pressure loading. As observed earlier for Ti coatings, 0.15-micrometer layers of B{sub 4}C had better gas retention properties than 2-micrometer layers, possibly because of fewer cracks. Permeation and fill strength issues for capsules with a full ablator thickness of B{sub 4}C are unresolved. 21 refs., 6 figs.

  20. Osteoarthitis of Leptin-Deficient ob/ob Mice in Response to Biomechanical Loading in Micro-CT

    Directory of Open Access Journals (Sweden)

    Hansjoerg Heep, Gero Hilken, Sebastian Hofmeister, Christian Wedemeyer

    2009-01-01

    Full Text Available Objective: Mechanotransduction is the mechanism that due to reacting chondrocytes on biomechanical loading of body mass. Higher biomechanical loading lead to increased degeneration of chondrocytes, whereas moderate loading is protecting. This suggests that body fat regulates bone metabolism first by means of hormonal factors and second that the effects of muscle and loading are signaling factors in mechanotransduction. Leptin, a peptide hormone produced predominantly by white fat cells, is one of these hormonal factors. The aim of this study was to investigate and measure the different effects of weight-bearing on trabecular bone formation in mice without the stimulation of leptin and with or without osteoarthritis. Materials and methods: 40 C57BL/ 6J ob/ob-mice in the age of 20 weeks have been devided into two groups with an ad-libitum-diet and with reduced diet. The hip- and knee-joints have been examinated in micro-CT-scan and histomorphologically. Results: Animals with an ad-libitum-diet were found to increase body weight significantly at the age of six weeks in comparison with lean mice. At the age of twenty weeks the obese mice were almost twice as heavy as the lean mice. Significant statistical differences are shown between the two groups for body weight and bone mineral density. Examination of trabecular bone in micro-CT revealed that the only statistically significant difference between the two groups was the trabecular number for the proximal femur. High weight-bearing insignificantly improved all trabecular bone parameters in the obese mice. Correlation was found between trabecular number and bone mineral density on the one hand and body weight on the other hand. The correlation between body weight and osteoarthritis shows a significant increase in grade of osteoarthritis as body weight increases in hip-joint and knee-joint but not in osteoarthritis-positive (OP versus osteoarthritis-negative (ON mices. The correlation of the hip

  1. RNA-Seq-basierte Isolierung des Resistenzgens Bs4C aus Paprika

    OpenAIRE

    Strauß, Tina

    2015-01-01

    Das Paprika Resistenzgen Bs4C aus Capsicum pubescens vermittelt Resistenz gegenüber Xanthomonas campestris pv. vesicatoria (Xcv)-Stämmen, die den (transcription activator-like) TAL-Effektor AvrBs4 exprimieren. Vorangegangene Arbeiten ließen vermuten, dass AvrBs4 die Expression von Bs4C transkriptionell induziert. In einem “proof of principle”-Experiment, wurde Bs4C unter Verwendung eines RNA-Seq-basierten Ansatzes isoliert. Unter 68 differentiell AvrBs4-induzierten Paprikagenen war jedoch nur...

  2. Al/ B4C Composites with 5 and 10 wt% Reinforcement Content Prepared by Powder Metallurgy

    International Nuclear Information System (INIS)

    The preparation, physical and mechanical properties of Al/ B4C composites with 5 and 10 wt.% reinforcement content were investigated. In order to obtain the feedstock with a low powder loading, B4C mixtures containing fine powders were investigated to obtain the optimal particle packing. The experimental results indicated that the fine containing 5 and 10 wt.% particles are able to prepare the feedstock with a good flowability. The composites fabricated by powder metallurgy have low densities and homogeneous microstructures. Additionally there is no interface reaction observed between the reinforcement and matrix by XRD analysis. The hardness of Al/ B4C composites prepared by powder metallurgy was high. (Author)

  3. Pycnogenol supplementation promotes lipolysis via activation of cAMP-dependent PKA in ob/ob mice and primary-cultured adipocytes.

    Science.gov (United States)

    Ho, Jin-Nyoung; Kim, Ok-Kyung; Nam, Da-Eun; Jun, Woojin; Lee, Jeongmin

    2014-01-01

    This study investigated the PKA-dependent inhibitory effect of pycnogenol (Pyc) on lipolysis using ob/ob mice and primary mouse adipocytes. Supplementation of Pyc at 30 mg/kg significantly reduced body weight gain and visceral fat mass. The serum and hepatic triglyceride (TG) and total cholesterol (TC) levels were reduced by Pyc supplementation, and high density lipoprotein (HDL)-cholesterol level significantly increased. In addition, hormone sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) mRNA levels increased with Pyc supplementation in adipose tissue of ob/ob mice. The treatment of primary cultured adipocytes with Pyc at 100 μg/mL significantly increased glycerol release, cAMP level by reduction of phosphodiestersae-3B (PDE3B), and HSL levels, but decreased protein levels of perilipin A and fatty acid synthetase (FAS). The PKA inhibitor (H89) clearly blocked the cellular levels of perilipin A and HSL, suggesting that Pyc promotes lipolysis of adipocytes through activation of cAMP-dependent PKA, resulting in induction of HSL and reduction of perilipin A. Therefore, this study may elucidate the possible mechanism of Pyc, which is a candidate for weight loss through stimulation of lipolysis. PMID:25866307

  4. OBS-Ethernet汇聚网卡的IP设计与实现%Design and implement of IP core for the assembly card in OBS-Ethernet network

    Institute of Scientific and Technical Information of China (English)

    卞燕如; 乐孜纯; 付明磊

    2011-01-01

    A novel design and implementation of OBS-Ethernet network assembly card based on Xilinx Spartan-3E is presented in this paper. A special SoC (system on chip) is built by means of microblaze which is used to design the IP core for OBS-Ethernet assembly card. The IP core is programmed by Verilog HDL language and debugged by EDK and ISE software.%OBS-Ethernet汇聚网卡以FPGA作为核心硬件,选用XILINX的Spartan 3E系列中的XC3S500E 芯片作为主芯片,在其上构建了基于MicroBlaze软核处理器的SOPC片上系统.根据MicroBlaze软核的开发环境,给出了实现OBS-Ethernet网络适配的IP核结构设计,使用VerilogHDL语言进行硬件实现,并在EDK软件平台和ISE软件平台进行了实验.

  5. Boron carbide (B{sub 4}C) coating. Deposition and testing

    Energy Technology Data Exchange (ETDEWEB)

    Azizov, E.; Barsuk, V. [Troitsk Institute for Innovation and Fusion Research (TRINITI), Moscow Region (Russian Federation); Begrambekov, L., E-mail: lbb@plasma.mephi.ru [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow (Russian Federation); Buzhinsky, O. [Troitsk Institute for Innovation and Fusion Research (TRINITI), Moscow Region (Russian Federation); Evsin, A.; Gordeev, A.; Grunin, A. [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow (Russian Federation); Klimov, N. [Troitsk Institute for Innovation and Fusion Research (TRINITI), Moscow Region (Russian Federation); Kurnaev, V. [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow (Russian Federation); Mazul, I. [Federal State Unitary Interprise Efremov Scientific Research Institute of Electrophysical Apparatus (NIIEFA Efremov), St-Peterburg (Russian Federation); Otroshchenko, V.; Putric, A. [Troitsk Institute for Innovation and Fusion Research (TRINITI), Moscow Region (Russian Federation); Sadovskiy, Ya.; Shigin, P.; Vergazov, S.; Zakharov, A. [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow (Russian Federation)

    2015-08-15

    Boron carbide was proposed as a material of in-situ protecting coating for tungsten tiles of ITER divertor. To prove this concept the project including investigation of regimes of plasma deposition of B{sub 4}C coating on tungsten and tests of boron carbide layer in ITER-like is started recently. The paper contends the first results of the project. The results of B{sub 4}C coating irradiation by the plasma pulses of QSPU-T plasma accelerator are presented. The new device capable of B{sub 4}C film deposition on tungsten and testing of the films and materials with ITER-like heat loads and ion- and electron irradiation is described. The results of B{sub 4}C coating deposition and testing of both tungsten substrate and coating are shown and discussed.

  6. Microstructure and Tensile Behaviour of B4C Reinforced ZA43 Alloy Composites

    Science.gov (United States)

    Adaveesh, B.; Halesh, G. M.; Nagaral, Madeva; Mohan Kumar, T. S.

    2016-09-01

    The work is carried out to investigate and study the mechanical properties of B4C reinforced ZA43 alloy metal matrix composites. In the present work ZA43 alloy is taken as the base matrix and B4C particulates as reinforcement material to prepare metal matrix composites by stir casting method. For metal matrix composites the reinforcement material was varied from 0 to 6 wt.% in steps of 3 wt.%. For each composite, the reinforcement particulates were preheated to a temperature of 300°C and dispersed into a vortex of molten ZA43 alloy. The microstructural characterization was done using scanning electron microscope. Mechanical properties like hardness, ultimate tensile strength and yield strength were evaluated as per ASTM standards. Further, scanning electron microphotographs revealed that there was uniform distribution of B4C particulates in ZA43 alloy matrix. Hardness, ultimate tensile strength and yield strength increased as wt.% of B4C increased in the base matrix.

  7. Enzyme kinetic studies of histone demethylases KDM4C and KDM6A

    DEFF Research Database (Denmark)

    Kristensen, Jan B L; Nielsen, Anders L; Jørgensen, Lars;

    2011-01-01

    To investigate ligand selectivity between the oncogenic KDM4C and tumor repressor protein KDM6A histone demethylases, KDM4C and KDM6A were enzymatically characterized, and subsequently, four compounds were tested for inhibitory effects. 2,4-dicarboxypyridine and (R)-N-oxalyl-O-benzyltyrosine (3......) are both known to bind to a close KDM4C homolog and 3 binds in the part of the cavity that accommodates the side chain in position 11 of histone 3. The inhibition measurements showed significant selectivity between KDM4C and KDM6A. This demonstrates that despite very similar active site topologies......, selectivity between Jumonji family histone demethylases can be obtained even with small molecule ligands....

  8. TL and OSL studies of carbon doped magnesium aluminate (MgAl2O4:C)

    Science.gov (United States)

    Raj, Sanu S.; Mishra, D. R.; Soni, Anuj; Grover, V.; Polymeris, G. S.; Muthe, K. P.; Jha, S. K.; Tyagi, A. K.

    2016-10-01

    The MgAl2O4:C has been synthesized by using two different methods by electron gun and vacuum assisted melting of MgAl2O4 in presence of graphite. The MgAl2O4:C phosphor thus developed by these two different methods have similar types of the TL/OSL defects with multiple overlapping TL glow peaks from 100 °C to 400 °C. The Computerized Curve De-convolution Analysis (CCDA) has been used to measure TL parameters such as thermal trap depth, frequency factor and order of kinetic associated with charge transfer process in TL phenomenon. The investigated TL/OSL results show that these two methods of incorporating carbon in MgAl2O4 have generated closely resemble the defects of similar types in MgAl2O4:C lattice. However, the MgAl2O4:C synthesized by electron gun shows relatively larger concentration of the TL/OSL defects as compared to MgAl2O4:C synthesized using vacuum assisted melting method. The photo-ionization cross-section (PIC) associated with fastest OSL component of MgAl2O4: C is found to be ∼ 0.5 times than that of fastest OSL component of commercially available dosimetric grade α-Al2O3:C. The MgAl2O4:C thus developed shows good dynamic OSL dose linearity from few mGy to 1 Gy. This work reveals that MgAl2O4:C could be developed as potential tissue equivalent OSL / TL material.

  9. A possible OB protostar associated with the molecular outflow in G34.4

    Science.gov (United States)

    Bronfman, L.; May, J.; Nuernberger, D.; Shepherd, D.

    1999-10-01

    The most conspicuous massive molecular outflow candidate identified in our CS(2-1) survey of UC HII regions (Bronfman et al 1996) is G34.4 (IRAS 18507+0121) in the I Galactic quadrant. At a distance of 3.8 kpc, it is near (about 11') the very bright HII region G34.3 (Carral & Welch 1992), embedded in the same GMC with a VLSR of 57 km/s. The CS velocity profile obtained with SEST shows very broad wings, about 25 km/s wide at the 0.1 K level, indicating strong outflow activity. Near infrared images of the field, 90'' in size (0.35'' per pixel), obtained with the du Pont 100'' Telescope at Las Campanas, show a remarkably reddenned source visible only in the K' filter, elongated in shape, about 15'' in extent. We have recently observed the G34.4 region, using the OVRO array, in the 3 mm continuum band and in the H13CO+ line, at a resolution of 5''. Most of the H13CO+ flux (33.64 Jy) comes from two strong cores; while one of these cores is closely associated with the ! NIR source, the other one is associated with a single, unresolved continuum source that has a total flux of 56.8 mJy. The mass of gas and dust in this second, possibly "star-less" core is estimated from the millimeter continuum to be approximately 355 MSun, consistent with the presence of a massive, embedded OB protostar. Bronfman, L., May, J., & Nyman, L. 1996, A&AS 115, 81 Carral & Welch 1992, ApJ 385, 244

  10. Preparedness of Ob/Gyn residents for fellowship training in gynecologic oncology

    Directory of Open Access Journals (Sweden)

    David W. Doo

    2015-04-01

    Full Text Available Residency training in obstetrics and gynecology is being challenged by increasingly stringent regulations and decreased operative experience. We sought to determine the perception of preparedness of incoming gynecologic oncology fellows for advanced surgical training in gynecologic oncology. An online survey was sent to gynecologic oncologists involved in fellowship training in the United States. They were asked to evaluate their most recent incoming clinical fellows in the domains of professionalism, level of independence/graduated responsibility, psychomotor ability, clinical evaluation and management, and academia and scholarship using a standard Likert-style scale. The response rate among attending physicians was 40% (n = 105/260 and 61% (n = 28/46 for program directors. Of those who participated, 49% reported that their incoming fellows could not independently perform a hysterectomy, 59% reported that they could not independently perform 30 min of a major procedure, 40% reported that they could not control bleeding, 40% reported that they could not recognize anatomy and tissue planes, and 58% reported that they could not dissect tissue planes. Fellows lacked an understanding of pathophysiology, treatment recommendations, and the ability to identify and treat critically ill patients. In the academic domain, respondents agreed that fellows were deficient in the areas of protocol design (54%, statistical analysis (54%, and manuscript writing (65%. These results suggest that general Ob/Gyn residency is ineffective in preparing fellows for advanced training in gynecologic oncology and should prompt a revision of the goals and objectives of resident education to correct these deficiencies.

  11. Study of influence content of TiB2 by reaction in situ B4C and TiC in mechanical properties on B4C ceramics

    International Nuclear Information System (INIS)

    The low density of ceramic materials promoted a change in research lines in the defense field. Research efforts and development directed to obtaining products of high density sintered of Al2O3, SiC and B4C, using different routes, both traditional as innovative, led to promising initial results, which justify the convergence of skills for the consolidation of research lines and the nationalization that sintered components of B4C with characteristics and properties compatible with the technical requirements established for the ballistic application. The low density of boron carbide (2.52 g/cm3) gives in the final product a weight approximately 30% lower than armor made of alumina (3.96 g/cm3). (author)

  12. The superluminal radio source 4c 39. 25 as relativistic jet prototype. El cuasar superluminal 4C 93. 25 como prototipo de jet relativistia

    Energy Technology Data Exchange (ETDEWEB)

    Alberdi, A.; Gomez, J.L.; Marcaide, J.M.

    1993-01-01

    We have developed a numerical code which solves the synchrotron radiation transfer equations to compute the total and polarized emission of bent shocked relativistic jets, and we have applied it to reproduce the compact structure, kinematic evolution of the superluminal radio source 4C 39.25 contains a bent relativistic jet which is misaligned relative to the observer near the core region, leading to a relatively low core brightness. (Author) 12 refs.

  13. Effects of temperature variation on LixFePO4/C (0

    Institute of Scientific and Technical Information of China (English)

    肖政伟; 张英杰; 胡国荣

    2015-01-01

    LiFePO4/C was prepared via solid state reaction and characterized with X-ray powder diffraction and charge–discharge test. As-prepared LiFePO4/C has a triphylite structure and exhibits an excellent rate capability and capacity retention. Electrochemical impedance spectroscopy (EIS) was applied to investigate LixFePO4/C (04/C is deeply delithiated at a relatively high temperature. EIS examination indicates that a temperature rise leads to a better reversibility, lower charge transfer resistance, higher exchange current densityJ0 and greater Li+ ion diffusion coefficient for the LixFePO4/C electrode process. The Li+ ion concentration in LixFePO4/C is potential to impact the Li+ ion diffusion coefficient, and a decrease in the former results in an increase in the latter.

  14. Spitzer observations of the Orion OB1 association: disk census in the low mass stars

    CERN Document Server

    Hernandez, Jesus; Briceño, C; Hartmann, L; Vivas, A K; Muzerolle, J; Downes, J; Allen, L; Gutermuth, R

    2007-01-01

    We present new Spitzer Space Telescope observations of two fields in the Orion OB1 association. We report here IRAC/MIPS observations for 115 confirmed members and 41 photometric candidates of the ~10 Myr 25 Orionis aggregate in the OB1a subassociation, and 106 confirmed members and 65 photometric candidates of the 5 Myr region located in the OB1b subassociation. The 25 Orionis aggregate shows a disk frequency of 6% while the field in the OB1b subassociation shows a disk frequency of 13%. Combining IRAC, MIPS and 2MASS photometry we place stars bearing disks in several classes: stars with optically thick disks (class II systems), stars with an inner transitional disks (transitional disk candidates) and stars with "evolved disks"; the last exhibit smaller IRAC/MIPS excesses than class II systems. In all, we identify 1 transitional disk candidate in the 25 Orionis aggregate and 3 in the OB1b field; this represents ~10% of the disk bearing stars, indicating that the transitional disk phase can be relatively fast...

  15. Non-thermal radio emission from colliding-wind binaries: modelling Cyg OB2 No. 8A and No. 9

    OpenAIRE

    Volpi, Delia; Blomme, Ronny; De Becker, Michael; Rauw, Gregor

    2010-01-01

    Some OB stars show variable non-thermal radio emission. The non-thermal emission is due to synchrotron radiation that is emitted by electrons accelerated to high energies. The electron acceleration occurs at strong shocks created by the collision of radiatively-driven stellar winds in binary systems. Here we present results of our modelling of two colliding wind systems: Cyg OB2 No. 8A and Cyg OB2 No. 9.

  16. Al4C3 Hydration Thermochemical Analysis for Burned Carbon-containing Refractories with Al

    Institute of Scientific and Technical Information of China (English)

    YANG Ding'ao; YU Zhiming; FAN Liuwu

    2003-01-01

    In this paper, X-ray diffractogram analysis and SEM observation of Al4 C3 formed at high temperature from carbon-containing refractories with Al have been carried out.Aluminum added to carbon-containing refractories reacts with C(s)to form Al4 C3(s) gradually during heating from 600 ℃ to 1200℃.It is considered that the interlocked structure of Al4 C3 plate crystals promotes the outstanding increase of hot modulus of rupture of carbon-containing refractories with Al. The HMOR of carbon-containing refractories added with Al additive from 0 to 5wt% increases by 2.8 times being from 6.5MPa to 18.2MPa.After a thermochemical calculation for hydration reaction processes of Al4 C3 and H2O(g), the equilibrium partial pressure chart of H2O(g)in H2O-Al4C3-Al(OH)3 system vs various temperatures has been attained . The H2O (g) partial pressure in the air needed for the Al4 C3 hydration reaction is no more than 10~18 atm at the temperature below 120℃.It is considered that the burned carbon-containing refractories with Al is extremely easy to hydrate and the cracking of burned carbon-containing refractories is generated because that the hydration expansion is 2.11 times during transforming from Al4 C3 to Al(OH)3.The fundamental measure against hydration of the refractories is to insulate the refractories from H2O(g)by various means such as pitch impregnation or other sealing materials.

  17. A multi-epoch XMM-Newton campaign on the core of the massive Cyg OB2 association

    CERN Document Server

    Rauw, Gregor

    2011-01-01

    Cyg OB2 is one of the most massive associations of O-type stars in our Galaxy. Despite the large interstellar reddening towards Cyg OB2, many studies, spanning a wide range of wavelengths, have been conducted to more clearly understand this association. X-ray observations provide a powerful tool to overcome the effect of interstellar absorption and study the most energetic processes associated with the stars in Cyg OB2. We analyse XMM-Newton data to investigate the X-ray and UV properties of massive O-type stars as well as low-mass pre-main sequence stars in Cyg OB2. We obtained six XMM-Newton observations of the core of Cyg OB2. In our analysis, we pay particular attention to the variability of the X-ray bright OB stars, especially the luminous blue variable candidate Cyg OB2 #12. We find that X-ray variability is quite common among the stars in Cyg OB2. Whilst short-term variations are restricted mostly to low-mass pre-main sequence stars, one third of the OB stars display long-term variations. The X-ray fl...

  18. Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.

    Directory of Open Access Journals (Sweden)

    Eugénie Ansseau

    Full Text Available Hundreds of double homeobox (DUX genes map within 3.3-kb repeated elements dispersed in the human genome and encode DNA-binding proteins. Among these, we identified DUX4, a potent transcription factor that causes facioscapulohumeral muscular dystrophy (FSHD. In the present study, we performed yeast two-hybrid screens and protein co-purifications with HaloTag-DUX fusions or GST-DUX4 pull-down to identify protein partners of DUX4, DUX4c (which is identical to DUX4 except for the end of the carboxyl terminal domain and DUX1 (which is limited to the double homeodomain. Unexpectedly, we identified and validated (by co-immunoprecipitation, GST pull-down, co-immunofluorescence and in situ Proximal Ligation Assay the interaction of DUX4, DUX4c and DUX1 with type III intermediate filament protein desmin in the cytoplasm and at the nuclear periphery. Desmin filaments link adjacent sarcomere at the Z-discs, connect them to sarcolemma proteins and interact with mitochondria. These intermediate filament also contact the nuclear lamina and contribute to positioning of the nuclei. Another Z-disc protein, LMCD1 that contains a LIM domain was also validated as a DUX4 partner. The functionality of DUX4 or DUX4c interactions with cytoplasmic proteins is underscored by the cytoplasmic detection of DUX4/DUX4c upon myoblast fusion. In addition, we identified and validated (by co-immunoprecipitation, co-immunofluorescence and in situ Proximal Ligation Assay as DUX4/4c partners several RNA-binding proteins such as C1QBP, SRSF9, RBM3, FUS/TLS and SFPQ that are involved in mRNA splicing and translation. FUS and SFPQ are nuclear proteins, however their cytoplasmic translocation was reported in neuronal cells where they associated with ribonucleoparticles (RNPs. Several other validated or identified DUX4/DUX4c partners are also contained in mRNP granules, and the co-localizations with cytoplasmic DAPI-positive spots is in keeping with such an association. Large muscle RNPs

  19. Identification of current attacks and their counter measures in Optical Burst Switched (OBS network

    Directory of Open Access Journals (Sweden)

    Siddharth Singh Chouhan

    2012-03-01

    Full Text Available As day by day application grows internet requires large amount of bandwidth. Optical Burst Switching (OBS is the next generation optical Internet with IP over WDM as the core architecture. It can achieve a balance between Optical Circuit Switching (OCS and Optical Packet Switching (OPS. Optical network supports huge bandwidth and transmits data at an average rate of 50Tb/s. But we need to exploit the fiber’s huge bandwidth through WDM which is the current favorite multiplexing technology in Optical communication networks. OBS is a trusted mechanism used for optical switching. Optical burst switching has been positioned as a viable means of implementing optical communication efficiently. This review paper identifies potential threats to security in OBS networks. Solutions in each category are examined, and research directions are presented.

  20. Synthesis and characterization of Fe 3 O 4 @C@Ag nanocomposites and their antibacterial performance

    Science.gov (United States)

    Xia, Haiqing; Cui, Bin; Zhou, Junhong; Zhang, Lulu; Zhang, Ji; Guo, Xiaohui; Guo, Huilin

    2011-09-01

    We synthesized Fe 3O 4@C@Ag nanocomposites through a combination of solvothermal, hydrothermal, and chemical redox reactions. Characterization of the resulting samples by X-ray diffraction, Fourier-transform infrared spectroscopy, field-emission scanning and transmission electron microscopy, and magnetic measurement is reported. Compared to Fe 3O 4@Ag nanocomposites, the Fe 3O 4@C@Ag nanocomposites showed enhanced antibacterial activity. The Fe 3O 4@C@Ag nanocomposites were able to almost entirely prevent growth of Escherichia coli when the concentration of Ag nanoparticles was 10 μg/mL. Antibacterial activity of the Fe 3O 4@C@Ag nanocomposites was maintained for more than 40 h at 37 °C. The intermediate carbon layer not only protects magnetic core, but also improves the dispersion and antibacterial activity of the silver nanoparticles. The magnetic core can be used to control the specific location of the antibacterial agent (via external magnetic field) and to recycle the residual silver nanoparticles. The Fe 3O 4@C@Ag nanocomposites will have potential uses in many fields as catalysts, absorbents, and bifunctional magnetic-optical materials.

  1. Vestibular impairment in Charcot-Marie-Tooth disease type 4C.

    Science.gov (United States)

    Pérez-Garrigues, Herminio; Sivera, Rafael; Vílchez, Juan Jesús; Espinós, Carmen; Palau, Francesc; Sevilla, Teresa

    2014-07-01

    Charcot-Marie-Tooth disease type 4C (CMT4C) is a hereditary neuropathy with prominent unsteadiness. The objective of the current study is to determine whether the imbalance in CMT4C is caused only by reduced proprioceptive input or if vestibular nerve involvement is an additional factor. We selected 10 CMT4C patients and 10 age-matched and sex-matched controls. We performed a comprehensive evaluation of the vestibular system, including video Head Impulse Test, bithermal caloric test, galvanic stimulation test and skull vibration-induced nystagmus test. None of the patients experienced dizziness, spontaneous or gaze-evoked nystagmus, but all had significant vestibular impairment when tested when compared to controls. Seven had completely unexcitable vestibular systems and abnormal vestibuloocular reflex. There was no correlation between the degree of vestibulopathy and age or clinical severity. Significant vestibular impairment is a consistent finding in CMT4C and is present early in disease evolution. The profound imbalance that is so disabling in these patients may result from a combination of proprioceptive loss and vestibular neuropathy, and this would modify the recommended rehabilitation strategies. PMID:24614092

  2. Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice

    DEFF Research Database (Denmark)

    Sørensen, Heidi; Brand, Christian L; Neschen, Susanne;

    2006-01-01

    synthesis. Glucagon mAb treatment for 5 days lowered plasma glucose and triglyceride levels, whereas 14 days of glucagon mAb treatment reduced A1C. In conclusion, acute and subchronic neutralization of endogenous glucagon improves glycemic control, thus supporting the contention that glucagon antagonism may......In type 2 diabetes, glucagon levels are elevated in relation to the prevailing insulin and glucose levels. The relative hyperglucagonemia is linked to increased hepatic glucose output (HGO) and hyperglycemia. Antagonizing the effects of glucagon is therefore considered an attractive target for...... treatment of type 2 diabetes. In the current study, effects of eliminating glucagon signaling with a glucagon monoclonal antibody (mAb) were investigated in the diabetic ob/ob mouse. Acute effects of inhibiting glucagon action were studied by an oral glucose tolerance test (OGTT) and by measurement of HGO...

  3. NEAR INFRARED DIFFUSE INTERSTELLAR BANDS TOWARD THE CYGNUS OB2 ASSOCIATION

    Energy Technology Data Exchange (ETDEWEB)

    Hamano, Satoshi; Kondo, Sohei; Sameshima, Hiroaki; Nakanishi, Kenshi; Kawakita, Hideyo [Laboratory of Infrared High-resolution Spectroscopy, Koyama Astronomical Observatory, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555 (Japan); Kobayashi, Naoto [Institute of Astronomy, School of Science, University of Tokyo, 2-21-1 Osawa, Mitaka, Tokyo 181-0015 (Japan); Ikeda, Yuji [Photocoding, 460-102 Iwakura-Nakamachi, Sakyo-ku, Kyoto, 606-0025 (Japan); Yasui, Chikako; Mizumoto, Misaki; Matsunaga, Noriyuki; Fukue, Kei; Yamamoto, Ryo; Izumi, Natsuko [Department of Astronomy, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo 113-0033 (Japan); Mito, Hiroyuki [Kiso Observatory, Institute of Astronomy, School of Science, The University of Tokyo, 10762-30 Mitake, Kiso-machi, Kiso-gun, Nagano, 397-0101 (Japan); Nakaoka, Tetsuya; Kawanishi, Takafumi; Kitano, Ayaka; Otsubo, Shogo [Department of Physics, Faculty of Sciences, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555 (Japan); Kinoshita, Masaomi, E-mail: hamano@cc.kyoto-su.ac.jp [Solar-Terrestrial Environment Laboratory, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8601 (Japan)

    2016-04-10

    We obtained the near-infrared (NIR) high-resolution (R ≡ λ/Δλ ∼ 20,000) spectra of the seven brightest early-type stars in the Cygnus OB2 association for investigating the environmental dependence of diffuse interstellar bands (DIBs). The WINERED spectrograph mounted on the Araki 1.3 m telescope in Japan was used to collect data. All 20 of the known DIBs within the wavelength coverage of WINERED (0.91 < λ < 1.36 μm) were clearly detected along all lines of sight because of their high flux density in the NIR wavelength range and the large extinction. The equivalent widths (EWs) of DIBs were not correlated with the column densities of C{sub 2} molecules, which trace the patchy dense component, suggesting that the NIR DIB carriers are distributed mainly in the diffuse component. On the basis of the correlations among the NIR DIBs both for stars in Cyg OB2 and stars observed previously, λλ10780, 10792, 11797, 12623, and 13175 are found to constitute a “family,” in which the DIBs are correlated well over the wide EW range. In contrast, the EW of λ10504 is found to remain almost constant over the stars in Cyg OB2. The extinction estimated from the average EW of λ10504 (A{sub V} ∼ 3.6 mag) roughly corresponds to the lower limit of the extinction distribution of OB stars in Cyg OB2. This suggests that λ10504 is absorbed only by the foreground clouds, implying that the carrier of λ10504 is completely destroyed in Cyg OB2, probably by the strong UV radiation field. The different behaviors of the DIBs may be caused by different properties of the DIB carriers.

  4. Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-Deficient Lep(ob/ob) Mice.

    Science.gov (United States)

    Bolze, Florian; Morath, Volker; Bast, Andrea; Rink, Nadine; Schlapschy, Martin; Mocek, Sabine; Skerra, Arne; Klingenspor, Martin

    2016-01-01

    Body weight loss of Lep(ob/ob) mice in response to leptin is larger than expected from the reduction in energy intake alone, suggesting a thermogenic action of unknown magnitude. We exploited the superior pharmacological properties of a novel long-acting leptin prepared via PASylation to study the contribution of its anorexigenic and thermogenic effects. PASylation, the genetic fusion of leptin with a conformationally disordered polypeptide comprising 600 Pro/Ala/Ser (PAS) residues, provides a superior way to increase the hydrodynamic volume of the fusion protein, thus retarding kidney filtration and extending plasma half-life. Here a single PAS(600)-leptin injection (300 pmol/g) resulted in a maximal weight reduction of 21% 6 days after application. The negative energy balance of 300 kJ/(4 d) was driven by a decrease in energy intake, whereas energy expenditure remained stable. Mice that were food restricted to the same extent showed an energy deficit of only 220 kJ/(4 d) owing to recurring torpor bouts. Therefore, the anorexigenic effect of PAS(600)-leptin contributes 75% to weight loss, whereas the thermogenic action accounts for 25% by preventing hypometabolism. In a second experiment, just four injections of PAS(600)-leptin (100 pmol/g) administered in 5- to 6-day intervals rectified the Lep(ob/ob) phenotype. In total, 16 nmol of PAS(600)-leptin per mouse triggered a weight loss of 43% within 20 days and normalized hypothermia and glucose homeostasis as well as hepatic steatosis. The beneficial properties of PAS(600)-leptin are substantiated by a comparison with previous studies in which approximately 400 nmol (∼25-fold) unmodified leptin was mandatory to achieve similar improvements. PMID:26492472

  5. Genistein supplementation prevents weight gain but promotes oxidative stress and inflammation in the vasculature of female obese ob/ob mice.

    Science.gov (United States)

    Simperova, Anna; Al-Nakkash, Layla; Faust, James J; Sweazea, Karen L

    2016-08-01

    Obesity, a state of chronic low-grade inflammation, is strongly associated with the development of hypertension and diabetes. Superoxide, a free radical elevated in obese individuals, promotes hypertension through scavenging the endogenous vasodilator nitric oxide. The hypothesis was a genistein-enriched diet would promote weight loss and reduce oxidative stress and inflammation in the vasculature of intact female ob/ob mice. Aortas and mesenteric arteries were isolated from female ob/ob mice fed genistein-free (0mg genistein/kg diet; n=6), standard chow (200-300mg genistein/kg diet; n=11) or genistein-enriched (600mg genistein/kg diet; n=9) diets for 4weeks. Sections of isolated vessels were labeled with the superoxide indicator dihydroethidium and fluorescence was measured by confocal microscopy. Protein expression of the inflammatory marker inducible nitric oxide synthase (iNOS) was measured in the perivascular adipose tissue (PVAT) surrounding each vessel and plasma concentrations of superoxide dismutase (SOD) were quantified. Genistein-enriched diet promoted less weight gain compared to animals fed standard chow (P=.008). Standard chow promoted increased superoxide in the aorta (P=.030) and mesenteric arteries (P=.024) compared to a diet devoid of genistein. At all tested concentrations, genistein significantly increased iNOS expression in mesenteric artery PVAT (vs. standard chow, P<.001; vs. genistein-enriched, P=.002) and tended to increase iNOS within the aortic PVAT (standard chow, P=.075) compared to the genistein-free group. Plasma SOD activity was significantly downregulated in genistein-enriched animals as compared to those fed a genistein-free diet (P=.028). In summary, although genistein prevents weight gain, it promotes vascular oxidative stress and inflammation in obese ovarian-intact female mice. PMID:27440533

  6. Research on the Four-Component Instructional Design Model(4C/ID)%四要素教学设计模型(4C/ID)研究

    Institute of Scientific and Technical Information of China (English)

    孙琼玲; 任翔

    2011-01-01

    通过对文献的研究和分析,目前国内关于4C/ID模型的研究主要关注:4C/ID模型的内涵、理论基础、构成要素以及4C/ID模型与其他模型的区别等;而国外的研究重点则是4C/ID模型在实践中的应用研究,从中我们可以得到一些启示。%After researching and analysis for literature,we find that the focus of 4C/ID model at present domestic concerns : Content,theory basis and elements of 4C/ID model,and difference between 4C/ID model and other models,etc;but focus on application of 4C/ID m

  7. Evaluation of metal content in perch of the Ob River basin

    OpenAIRE

    Osipova, Nina Aleksandrovna; Stepanova, Kristina Dmitrievna; Matveenko, Irina Alekseevna

    2015-01-01

    The geochemical features of river perch in the River Ob basin have been studied (the upper and middle reaches of the Ob River and the lower reach of the Tom River). The contents of Ag, Bi, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Sn, W, Zn, Hg in perch's soft tissue are defined by the methods of ICP AES and stripping voltammetry, that of mercury in bones - by the atomic absorption method using mercury analyzer РА-915+. The distribution series of metal absolute concentrations in perch's soft tissue...

  8. Refined crystal structure of cubic skeletov zinc borate Zn4O[B6O12

    International Nuclear Information System (INIS)

    Cubic crystals of the Zn4O[B6O12] composition obtained from the ZnO-B2O3-Li2O(Na2O,K2O)-H2O system with the NnO addition are studied in the temperature range of 250-450 deg C and at the pressure of 1000 atm. It is established that stable crystallization zones are characteristic for the above compound. The crystals are colourless and possess luminescent properties. Interplane distances, cubic lattice parameters and interatomic distances in the Zn4O[B6O12] structure are determined

  9. Analyzing the Effects of Nitrogen Deficiency on the PHB Production of Methylosinus trichosporium OB3b

    Science.gov (United States)

    Kyauk, E.

    2011-12-01

    Polyhydroxybutyrate (PHB) is a biodegradable thermoplastic that is produced by various microorganisms. Because of its potential to replace conventional plastics, it has been closely researched in the past few years. Methanotrophic bacteria, bacteria that consume methane, produce this bioplastic when it lacks certain nutrients. The utilization of methane to produce PHB shows much promise as methane is a cheap, plentiful gas. In this study, we observed the methanotroph, Methylosinus trichosporium OB3b , and its yield of PHB in the absence of nitrogen. The optical density of Methylosinus trichosporium OB3b was measured in order to observe cell growth and PHB production patterns over a 48 hour period.

  10. Hot pressing of B{sub 4}C/SiC composites

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, F.C.; Turhan, E.; Yesilcubuk, S.A.; Addemir, O. [Ystanbul Technical University, Faculty of Chemistry and Metallurgy, Materials and Metallurgical Engineering Dept., Maslak-Ystanbul (Turkey)

    2005-07-01

    B{sub 4}C/SiC ceramic composites containing 10-20-30 vol % SiC were prepared by hot pressing method. The effect of SiC addition and hot pressing temperature on sintering behaviour and mechanical properties of hot pressed composites were investigated. Microstructures of hot pressed samples were examined by SEM technique. Three different temperatures (2100 deg. C, 2200 deg. C and 2250 deg. C) were used to optimize hot pressing temperature applying 100 MPa pressure under argon atmosphere during the sintering procedure. The highest relative density of 98.44 % was obtained by hot pressing at 2250 deg. C. However, bending strengths of B{sub 4}C/SiC composite samples were lower than monolithic B{sub 4}C in all experimental conditions. (authors)

  11. The design, fabrication and properties of B4C/Al neutron absorbers

    International Nuclear Information System (INIS)

    Neutron absorber is used for the criticality safety during the storage or transportation of spent nuclear fuel. In this work, the metal matrix composite with good mechanical property and thermal neutron absorbing ability was investigated based on B4C/Al neutron radiation shielding material. The composition ratio for B4C/Al composite was firstly designed and the dependence of the neutron transmission on the thickness of the material was calculated. By vacuum hot-pressing technique at a low temperature, the neutron absorbers with high concentration of B4C were fabricated. Furthermore, the corresponding microstructure, physical, mechanical and corrosion properties as well as fracture surface were analyzed, proving that the developed composites can shield the neutron radiation as effectively as cadmium materials

  12. Neutron absorption of Al-Si-Mg-B{sub 4}C composite

    Energy Technology Data Exchange (ETDEWEB)

    Abdullah, Yusof, E-mail: yusofabd@nuclearmalaysia.gov.my; Yusof, Mohd Reusmaazran [Malaysian Nuclear Agency, 43000, Bangi Selangor (Malaysia); Ibrahim, Anis Syukriah; Daud, Abdul Razak [Department of Applied Physics, Faculty of Science & Technology, National University of Malaysia, 43600, Bangi Selangor (Malaysia)

    2016-01-22

    Al-Si-Mg-B{sub 4}C composites containing 2-8 wt% of B{sub 4}C were prepared by stir casting technique. Homogenization treatment was carried out at temperatures of 540°C for 4 houra and followed by ageing at 180°C for 2 houra. Microstructure and phase identification were studied by scanning electron microscopy (SEM) and X-ray diffraction (XRD) respectively. Neutron absorption study was investigated using neutron source Am/Be{sup 241}. The result indicated that higher B{sub 4}C content improved the neutron absorption property. Meanwhile homogeneity of the composite was increased by ageing processes. This composite is potential to be used as neutron shielding material especially for nuclear reactor application.

  13. sup 1 sup 4 C dating of the Niya site in the Tarim Basin

    CERN Document Server

    Yonenobu, H

    2000-01-01

    The sup 1 sup 4 C ages were determined for wood samples collected from the Niya site in the Tarim Basin, China. The calendar sup 1 sup 4 C ages are the oldest in the northern part (800-100 cal BC) and the youngest (140-620 cal AD) in the southern part. The results suggest that ancient Niya had moved southward during the period of ca. 2300-1600 BP. The ages in the middle and the southern parts are consistent with the previous studies of old documents.

  14. Note on thermodynamic instability of M4C3-type carbides of gallium group metals

    International Nuclear Information System (INIS)

    The paper deals with thermodynamic stability of hypothetical solid binary M4C3 carbides of gallium, indium and thallium. Heats of formation whose contribution to the stability of these compounds is dominant, were estimated by two independent methods: semiempirical theory of Miedema and empirical trends in the heats of formation of nitrides and carbides of Group III elements. Entropies were calculated with the use of the Cantor equation. The estimated values suggest that M4C3 carbides of gallium, indium and thallium are thermodynamically unstable with regard to their decomposition of elements. (Author)

  15. Synthesis, Characterization and Properties of LiFePO4/C Cathode Material

    Institute of Scientific and Technical Information of China (English)

    ZHOU Xin-wen; ZHAN Dan; WANG Li-na; LIU Qiao-yun; ZONG Hong-xing; ZHANG Ke-li

    2005-01-01

    Lithium iron phosphate coated with carbon(LiFePO4/C) was synthesized by improved solid-state reaction using comparatively lower temperature and fewer sintering time. The carbon came from citric acid, which acted as a new carbon source. It was characterized by thermogravimetry and differential thermal analysis (TG/DTA), X ray diffractometer (XRD), Element Analysis (EA) and Scanning electron microscope (SEM). We also studied the electrochemical properties of the material. The first discharge capacity of the and retained 95 % of the initial capacity after 100 cycles. The LiFePO4/C obtained shows a good electrochemical capacity and cycle ability at a large current density.

  16. Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)

    DEFF Research Database (Denmark)

    Leurs, Ulrike; Clausen, Rasmus P; Kristensen, Jesper L;

    2012-01-01

    The human histone demethylases of the KDM4 (JMJD2) family have been associated to diseases such as prostate and breast cancer, as well as X-linked mental retardation. Therefore, these enzymes are considered oncogenes and their selective inhibition might be a possible therapeutic approach to treat...... cancer. Here we describe a heterocyclic ring system library screened against the histone demethylase KDM4C (JMJD2C) in the search for novel inhibitory scaffolds. A 4-hydroxypyrazole scaffold was identified as an inhibitor of KDM4C; this scaffold could be employed in the further development of novel...

  17. Hellenic subduction earthquake locations including OBS, ocean bottom seismometers and hints at shallow slab structure from teleseismic conversions: A pilot experiment.

    Science.gov (United States)

    Sachpazi, M.; Laigle, M.; Charalampakis, M.; Diaz, J.; Gesret, A.; Sokos, E.; Petrou, P.; Flueh, E.; Nicolich, R.; Hirn, A.

    2010-05-01

    In the frame of the European Union "THALES WAS RIGHT" project on seismogenic zones in European subductions and of the European Union "SALVADOR" programme of IfM-GEOMAR for the access to OBS, ocean bottom seismometers, we have deployed in early June 2006 and for 5 months an onshore-offshore array in the SW part of the Hellenic subduction, the area between the south west tip of Peloponissos and Crete. The array consisted of 5, three component OBS and of up to 15 land seismometers. This provided for the first time a constraint on the hypocentral locations of local earthquakes offshore, that up to then were poorly located because of an insufficient azimuthal coverage, since all the permanent stations are on land on one side. Comparison of the routinely located hypocenters by the permanent array with those located by the special local onshore/offshore local array shows that some background seismicity may be mislocated by several tens of kilometers with for instance small earthquakes of the upper part of the plate boundary SW of Crete-Peloponissos having been located as deep earthquakes in the SW Aegean because of lack of constraint to the SW. This survey was organized early in the THALES WAS RIGHT project, in order to provide a reference observation period for the project. This proved a valuable effort since it provided this basis just a year before the major earthquake for decades in the region. This allows to reveal temporal patterns of seismicity, thus constrained by the addition of offshore observations. Indeed a very strong earthquake for the region occurred on February 14, 2008, SW offshore Methoni. Differential location of its hypocenter can be made by land stations, with respect to hypocenters of the pre-seismic period phase that had been accurately located with OBS nearby. This allows to constrain in retrospect the future hypocenter of the M=6.9 earthquake as a geographical gap in smaller earthquake occurrence in the months before. Preliminary results from the

  18. Advective transport observations with MODPATH-OBS--documentation of the MODPATH observation process

    Science.gov (United States)

    Hanson, R.T.; Kauffman, L.K.; Hill, M.C.; Dickinson, J.E.; Mehl, S.W.

    2013-01-01

    The MODPATH-OBS computer program described in this report is designed to calculate simulated equivalents for observations related to advective groundwater transport that can be represented in a quantitative way by using simulated particle-tracking data. The simulated equivalents supported by MODPATH-OBS are (1) distance from a source location at a defined time, or proximity to an observed location; (2) time of travel from an initial location to defined locations, areas, or volumes of the simulated system; (3) concentrations used to simulate groundwater age; and (4) percentages of water derived from contributing source areas. Although particle tracking only simulates the advective component of conservative transport, effects of non-conservative processes such as retardation can be approximated through manipulation of the effective-porosity value used to calculate velocity based on the properties of selected conservative tracers. This program can also account for simple decay or production, but it cannot account for diffusion. Dispersion can be represented through direct simulation of subsurface heterogeneity and the use of many particles. MODPATH-OBS acts as a postprocessor to MODPATH, so that the sequence of model runs generally required is MODFLOW, MODPATH, and MODPATH-OBS. The version of MODFLOW and MODPATH that support the version of MODPATH-OBS presented in this report are MODFLOW-2005 or MODFLOW-LGR, and MODPATH-LGR. MODFLOW-LGR is derived from MODFLOW-2005, MODPATH 5, and MODPATH 6 and supports local grid refinement. MODPATH-LGR is derived from MODPATH 5. It supports the forward and backward tracking of particles through locally refined grids and provides the output needed for MODPATH_OBS. For a single grid and no observations, MODPATH-LGR results are equivalent to MODPATH 5. MODPATH-LGR and MODPATH-OBS simulations can use nearly all of the capabilities of MODFLOW-2005 and MODFLOW-LGR; for example, simulations may be steady-state, transient, or a combination

  19. 29 CFR 4.163 - Section 4(c) of the Act.

    Science.gov (United States)

    2010-07-01

    ...) Collective bargaining agreement must be applicable to work performed on the predecessor contract. Section 4(c... contract of a wage determination based on the predecessor contractor's collective bargaining agreement... identifiable contract work requirements into new or consolidated contracts, provided that the new...

  20. Electrochemical Behavior of Al-B4C Metal Matrix Composites in NaCl Solution

    Directory of Open Access Journals (Sweden)

    Yu-Mei Han

    2015-09-01

    Full Text Available Aluminum based metal matrix composites (MMCs have received considerable attention in the automotive, aerospace and nuclear industries. One of the main challenges using Al-based MMCs is the influence of the reinforcement particles on the corrosion resistance. In the present study, the corrosion behavior of Al-B4C MMCs in a 3.5 wt.% NaCl solution were investigated using potentiodynamic polarization (PDP and electrochemical impedance spectroscopy (EIS techniques. Results indicated that the corrosion resistance of the composites decreased when increasing the B4C volume fraction. Al-B4C composite was susceptible to pitting corrosion and two types of pits were observed on the composite surface. The corrosion mechanism of the composite in the NaCl solution was primarily controlled by oxygen diffusion in the solution. In addition, the galvanic couples that formed between Al matrix and B4C particles could also be responsible for the lower corrosion resistance of the composites.

  1. Tribological behavior of liquid metallurgy-processed AA 6061-B4C composites

    International Nuclear Information System (INIS)

    Aluminum metal matrix composites (AMMCs) possess improved properties compared to their monolithic counterparts and serve as a reliable alternative to replace them for applications that are considered as their niche. In the present investigation, 6061 Al alloy-10 wt% B4C composite is fabricated through liquid metallurgy stir casting technique and analyzed for its tribological characteristics. The uniform distribution of B4C reinforcement particles in the composite is achieved by the above route and is characterized using microstructure analysis and x-ray diffraction spectrum. The dry wear tests have been conducted under ambient conditions using a pin-on-disc tribometer. The worn surface and debris of the composite are also characterized using a scanning electron microscope (SEM) and energy-dispersive x-ray spectroscopy (EDS). It is found that the combination of adhesion, delamination and abrasion constitute the predominant wear mechanism and this is influenced by the B4C particles, applied load, sliding distance and speed. The wear and friction coefficient increase with increase in applied load for all the load conditions studied. While the sliding speed fosters the engendering of a mechanically mixed layer (MML) to reduce the wear and friction coefficient, in contrast, the increase in sliding distance scuttles the MML formation owing to abrasion induced by the hard B4C particles. (paper)

  2. Synthesis and cytotoxic activity of 2,5-disubstituted pyrimido [5,4-c] quinoline derivatives

    Institute of Scientific and Technical Information of China (English)

    Fan Zhang; Xin Zhai; Li Juan Chen; Jian Guo Qi; Bo Cui; Yu Cheng Gu; Ping Gong

    2011-01-01

    A series of 2,5-disubstituted pyrimido[5,4-c]quinoline derivatives were synthesized and their cytotoxic activity against H460, HT-29 and MDA-MB-231 cell lines was evaluated in vitro. It was found that most of the tested compounds especially compound 17, shown stronger activity to the selected three cell lines than ZM447439.

  3. Hypovalency--a kinetic-energy density description of a 4c-2e bond.

    Science.gov (United States)

    Jacobsen, Heiko

    2009-06-01

    A bond descriptor based on the kinetic energy density, the localized-orbital locator (LOL), is used to characterize the nature of the chemical bond in electron deficient multi-center bonds. The boranes B(2)H(6), B(4)H(4), B(4)H(10), [B(6)H(6)](2-), and [B(6)H(7)](-) serve as prototypical examples of hypovalent 3c-2e and 4c-2e bonding. The kinetic energy density is derived from a set of Kohn-Sham orbitals obtained from pure density functional calculations (PBE/TZVP), and the topology of LOL is analyzed in terms of (3,-3) attractors (Gamma). The B-B-B and B-H-B 3c-2e, and the B-B-H-B 4c-2e bonding situations are defined by their own characteristic LOL profiles. The presence of one attractor in relation to the three or four atoms that are engaged in electron deficient bonding provides sufficient indication of the type of 3c-2e or 4c-2e bond present. For the 4c-2e bond in [B(6)H(7)](-) the LOL analysis is compared to results from an experimental QTAIM study. PMID:19452076

  4. Soil Moisture Active Passive Mission L4_C Data Product Assessment (Version 2 Validated Release)

    Science.gov (United States)

    Kimball, John S.; Jones, Lucas A.; Glassy, Joseph; Stavros, E. Natasha; Madani, Nima; Reichle, Rolf H.; Jackson, Thomas; Colliander, Andreas

    2016-01-01

    The SMAP satellite was successfully launched January 31st 2015, and began acquiring Earth observation data following in-orbit sensor calibration. Global data products derived from the SMAP L-band microwave measurements include Level 1 calibrated and geolocated radiometric brightness temperatures, Level 23 surface soil moisture and freezethaw geophysical retrievals mapped to a fixed Earth grid, and model enhanced Level 4 data products for surface to root zone soil moisture and terrestrial carbon (CO2) fluxes. The post-launch SMAP mission CalVal Phase had two primary objectives for each science product team: 1) calibrate, verify, and improve the performance of the science algorithms, and 2) validate accuracies of the science data products as specified in the L1 science requirements. This report provides analysis and assessment of the SMAP Level 4 Carbon (L4_C) product pertaining to the validated release. The L4_C validated product release effectively replaces an earlier L4_C beta-product release (Kimball et al. 2015). The validated release described in this report incorporates a longer data record and benefits from algorithm and CalVal refinements acquired during the SMAP post-launch CalVal intensive period. The SMAP L4_C algorithms utilize a terrestrial carbon flux model informed by SMAP soil moisture inputs along with optical remote sensing (e.g. MODIS) vegetation indices and other ancillary biophysical data to estimate global daily net ecosystem CO2 exchange (NEE) and component carbon fluxes for vegetation gross primary production (GPP) and ecosystem respiration (Reco). Other L4_C product elements include surface (10 cm depth) soil organic carbon (SOC) stocks and associated environmental constraints to these processes, including soil moisture and landscape freeze/thaw (FT) controls on GPP and respiration (Kimball et al. 2012). The L4_C product encapsulates SMAP carbon cycle science objectives by: 1) providing a direct link between terrestrial carbon fluxes and

  5. Degradation of Chlorinated Aliphatic Hydrocarbons by Methylosinus trichosporium OB3b Expressing Soluble Methane Monooxygenase

    NARCIS (Netherlands)

    Oldenhuis, Roelof; Vink, Ruud L.J.M.; Janssen, Dick B.; Witholt, Bernard

    1989-01-01

    Degradation of trichloroethylene (TCE) by the methanotrophic bacterium Methylosinus trichosporium OB3b was studied by using cells grown in continuous culture. TCE degradation was a strictly cometabolic process, requiring the presence of a cosubstrate, preferably formate, and oxygen. M. trichosporium

  6. The Galaxy Kinematics from OB Stars with Proper Motions from the Gaia DR1 Catalog

    CERN Document Server

    Bobylev, V V

    2016-01-01

    We consider two previously studied samples of OB stars with different distance scales. The first one consists of 98 massive spectroscopic binary stars with photometric distances, and the second one consists on 140 OB stars with the distances determined along the lines of interstellar calcium. The OB stars are located at distances up to 7 kpc from the Sun. They are identified with the Gaia DR1 catalog. It is shown that the use of the proper motions, taken from the Gaia DR1 catalog, allows to reduce random errors of determination of the Galactic rotation parameters in comparison with the previously known ones. From the analysis of 208 OB stars from the Gaia DR1 catalog with proper motions and parallaxes with relative errors less than 200% we found the Galactic kinematic parameters. In addition the Galactic rotation parameters were obtained from only line-of-sight velocities of the same stars. From the comparison of the two values of \\Omega^{'}_0 a distance scale of the Gaia DR1 catalog was determined as a value...

  7. OB Associations, Wolf-Rayet Stars, and the Origin of Galactic Cosmic Rays

    CERN Document Server

    Binns, W R; Arnould, M; Cummings, A C; De Nolfo, G A; Goriely, S; Israel, M H; Leske, R A; Mewaldt, R A; Meynet, G; Scott, L M; Stone, E C; Von Rosenvinge, T T

    2007-01-01

    We have measured the isotopic abundances of neon and a number of other species in the galactic cosmic rays (GCRs) using the Cosmic Ray Isotope Spectrometer (CRIS) aboard the ACE spacecraft. Our data are compared to recent results from two-component Wolf-Rayet (WR) models. The three largest deviations of galactic cosmic ray isotope ratios from solar-system ratios predicted by these models, 12C/16O, 22Ne/20Ne, and 58Fe/56Fe, are very close to those observed. All of the isotopic ratios that we have measured are consistent with a GCR source consisting of ~20% of WR material mixed with ~80% material with solar-system composition. Since WR stars are evolutionary products of OB stars, and most OB stars exist in OB associations that form superbubbles, the good agreement of our data with WR models suggests that OB associations within superbubbles are the likely source of at least a substantial fraction of GCRs. In previous work it has been shown that the primary 59Ni (which decays only by electron-capture) in GCRs has...

  8. ObsPack: a framework for the preparation, delivery, and attribution of atmospheric greenhouse gas data

    NARCIS (Netherlands)

    Masarie, K. A.; Peters, W.; Jacobson, A. R.; Tans, P. P.

    2014-01-01

    Observation Package (ObsPack) is a framework designed to bring together atmospheric greenhouse gas observations from a variety of sampling platforms, prepare them with specific applications in mind, and package and distribute them in a self-consistent and well-documented product. Data products creat

  9. ObsPack: a framework for the preparation, delivery, and attribution of atmospheric greenhouse gas measurements

    NARCIS (Netherlands)

    Masarie, K. A.; Peters, W.; Jacobson, A. R.; Tans, P. P.

    2014-01-01

    Observation Package (ObsPack) is a framework designed to bring together atmospheric greenhouse gas observations from a variety of sampling platforms, prepare them with specific applications in mind, and package and distribute them in a self-consistent and well-documented product. Data products creat

  10. Uptake and effect of rare earth elements on gene expression in Methylosinus trichosporium OB3b.

    Science.gov (United States)

    Gu, Wenyu; Farhan Ul Haque, Muhammad; DiSpirito, Alan A; Semrau, Jeremy D

    2016-07-01

    It is well known that Methylosinus trichosporium OB3b has two forms of methane monooxygenase (MMO) responsible for the initial conversion of methane to methanol, a cytoplasmic (soluble) methane monooxygenase and a membrane-associated (particulate) methane monooxygenase, and that copper strongly regulates expression of these alternative forms of MMO. More recently, it has been discovered that M. trichosporium OB3b has multiple types of the methanol dehydrogenase (MeDH), i.e. the Mxa-type MeDH (Mxa-MeDH) and Xox-type MeDH (Xox-MeDH), and the expression of these two forms is regulated by the availability of the rare earth element (REE), cerium. Here, we extend these studies and show that lanthanum, praseodymium, neodymium and samarium also regulate expression of alternative forms of MeDH. The effect of these REEs on MeDH expression, however, was only observed in the absence of copper. Further, a mutant of M. trichosporium OB3b, where the Mxa-MeDH was knocked out, was able to grow in the presence of lanthanum, praseodymium and neodymium, but was not able to grow in the presence of samarium. Collectively, these data suggest that multiple levels of gene regulation by metals exist in M. trichosporium OB3b, but that copper overrides the effect of other metals by an as yet unknown mechanism. PMID:27190151

  11. The Unit control of an acquisition system for ocean bottom seismometer (OBS)

    OpenAIRE

    Carreras Pons, Normandino; Roset Juan, Francesc Xavier; Shariat Panahi, Shahram; Artero Delgado, Carola; Manuel Lázaro, Antonio; Owen, Tim; Antonijuan Rull, Josefina

    2012-01-01

    In this paper we talk about an acquisition system for seismic data. The Ocean Bottom Seismometer (OBS) is equipment designed to obtain the seismic marine data from the seabed. The main part of this paper is based in an application which controls the acquisition data of four measurement channels. This system has been tested in lab, getting the corresponding results.

  12. Atmospheric CO along the Trans-Siberian Railroad and River Ob: source identification using isotope analysis

    NARCIS (Netherlands)

    Tarasova, O.A.; Brenninkmeijer, C.A.M.; Assonov, S.S.; Elansky, N.F.; Röckmann, T.; Sofiev, M.A.

    2007-01-01

    The concentration, radiocarbon (14C) and stable isotope (13C and 18O) content of CO have been determined in air samples collected across Russia (about 8,500 km) and along the Ob river during the summer of 1999 to study the CO sources and sinks. An instrumented carriage on the Trans-Siberian railway

  13. Kinetics of Chlorinated Hydrocarbon Degradation by Methylosinus trichosporium OB3b and Toxicity of Trichloroethylene

    NARCIS (Netherlands)

    Oldenhuis, Roelof; Oedzes, Johannes Y.; Waarde, Jacob J. van der; Janssen, Dick B.

    1991-01-01

    The kinetics of the degradation of trichloroethylene (TCE) and seven other chlorinated aliphatic hydrocarbons by Methylosinus trichosporium OB3b were studied. All experiments were performed with cells grown under copper stress and thus expressing soluble methane monooxygenase. Compounds that were re

  14. Epidémie d’obésité : comment lutter

    Directory of Open Access Journals (Sweden)

    Poulain Jean‐Pierre

    2003-03-01

    Full Text Available L’obésité peut être l’objet d’un double regard sociologique. Le premier, adoptant la posture de recherche empiriste, positiviste et déterministe de l’épidémiologie médicale, accepte l’idée que l’obésité est un problème de santé publique et prend en charge l’identification des dimensions sociales associées à cette morbidité. Il s’intéresse à la distribution sociale de l’obésité, repère le rôle de la stigmatisation des obèses dans les sociétés développées. Il s’attache à identifier les fonctions de l’alimentation dans la transition épidémiologique et cherche à comprendre l’impact de la modernité alimentaire sur le développement de cette pathologie. Mais le regard sociologique peut aussi prendre l’obésité comme une construction sociale. Il met alors l’accent sur le relativisme historique et culturel des représentations qui s’agrégent sur cet état. Il cherche à décrire l’émergence, la diffusion et l’acceptation de l’idée que l’obésité est un problème de santé publique. Il montre comment la médicalisation de l’obésité déborde aujourd’hui sur l’alimentation en général et déconstruit les hypothèses implicites des campagnes nutritionnelles de prévention. De cette confrontation, un champ de recherche nouveau émerge, à l’interface des sciences de la nutrition et de la socio‐anthropologie de l’alimentation, dont l’objet est de mettre au jour la complexité des décisions alimentaires

  15. Purification and characterization of oligonucleotide binding (OB)-fold protein from medicinal plant Tinospora cordifolia.

    Science.gov (United States)

    Amir, Mohd; Haque, Md Anzarul; Wahiduzzaman; Dar, Mohammad Aasif; Islam, Asimul; Ahmad, Faizan; Hassan, Md Imtaiyaz

    2016-01-01

    The oligonucleotide binding fold (OB-fold) is a small structural motif present in many proteins. It is originally named for its oligonucleotide or oligosaccharide binding properties. These proteins have been identified as essential for replication, recombination and repair of DNA. We have successfully purified a protein contains OB-fold from the stem of Tinospora cordifolia, a medicinal plants of north India. Stems were crushed and centrifuged, and fraction obtained at 60% ammonium sulphate was extensively dialyzed and applied to the weak anion exchange chromatography on Hi-Trap DEAE-FF in 50mM Tris-HCl buffer at pH 8.0. Eluted fractions were concentrated and applied to gel filtration column to get pure protein. We observed a single band of 20-kDa on SDS-PAGE. Finally, the protein was identified as OB-fold by MALDI-TOF. The purified OB-fold protein was characterized for its secondary structural elements using circular dichroism (CD) in the far-UV region. Generally the OB-fold has a characteristic feature as five-stranded beta-sheet coiled to form a closed beta- barrel. To estimate its chemical stability, guanidinium chloride-induced denaturation curve was followed by observing changes in the far-UV CD as a function of the denaturant concentration. Analysis of this denaturation curve gave values of 8.90±0.25kcalmol(-1) and 3.78±0.18M for ΔGD° (Gibbs free energy change at 25°C) and Cm (midpoint of denaturation), respectively. To determine heat stability parameters of OB-fold protein, differential scanning calorimetry was performed. Calorimetric values of ΔGD°, Tm (midpoint of denaturation), ΔHm (enthalpy change at Tm), and ΔCp (constant-pressure heat capacity change) are 9.05±0.27kcalmol(-1), 85.2±0,3°C, 105±4kcalmol(-1) and 1.6±0.08kcalmol(-1)K(-1). This is the first report on the isolation, purification and characterization of OB-fold protein from a medicinal plant T. cordifolia. PMID:26613539

  16. Adult Workplace Learning Based on 4C Marketing Theory%基于营销学4C 理论的成人工作场所学习

    Institute of Scientific and Technical Information of China (English)

    徐君; 邵庆

    2015-01-01

    Compared with other forms of learning approach , workplace learning has various advantages ,such as clear goals , various forms , obvious effects and so on . It has been one of the important methods of adult learning ,and is being paid attention to increasingly . The 4C marketing theory includes 4 parts :customer ,cost ,convenience ,communication .It has theoretical guidance and practical value to open up the new field - adult workplace learning ,and promote the development of workplace learning theory . On the basics of the 4C marketing theory , we should promote adult workplace learning by the means of meeting consumers’ requirements , reducing cost , providing convenience and effective communication .%工作场所学习相对于其他成人学习方式而言具有目标明确、形式多样、效果明显等优势,已成为成人学习的一种重要方式并日益受到重视。营销学的4C理论由消费者、成本、便利和沟通四个基本要素构成,对于开辟成人工作场所这一“新疆域”,促进工作场所学习的大力发展具有理论指导和实践操作价值。基于此,应从满足双方需求、降低物质和精神成本、提供各种便利条件以及有效沟通四个方面促进成人工作场所学习。

  17. ObsPy: A Python Toolbox for Seismology and Seismological Observatories

    Science.gov (United States)

    Krischer, Lion; Megies, Tobias; Barsch, Robert; Beyreuther, Moritz; Wassermann, Joachim

    2013-04-01

    Python combines the power of a full-blown programming language with the flexibility and accessibility of an interactive scripting language. Its extensive standard library and large variety of freely available high quality scientific modules cover most needs in developing scientific processing workflows. ObsPy extends Python's capabilities to fit the specific needs that arise when working with seismological data. It a) comes with a continuously growing signal processing toolbox that covers most tasks common in seismological analysis, b) provides read and write support for many common waveform, station and event metadata formats and c) enables access to various data centers, webservices and databases to retrieve waveform data and station/event metadata. In combination with mature and free Python packages like NumPy, SciPy, Matplotlib, IPython and PyQt, ObsPy makes it possible to develop complete workflows in Python, ranging from reading locally stored data or requesting data from one or more different data centers via signal analysis and data processing to visualization in GUI and web applications, output of modified/derived data and the creation of publication-quality figures. All functionality is extensively documented and the ObsPy Tutorial and Gallery give a good impression of the wide range of possible use cases. ObsPy is tested and running on Linux, OS X and Windows and comes with installation routines for these systems. ObsPy is developed in a test-driven approach and is available under the GPL/LGPLv3 open source licences. Users are welcome to request help, report bugs, propose enhancements or contribute code via either the user mailing list or the project page on GitHub.

  18. ObsPy: A Python Toolbox for Seismologists, Seismological Observatories and Data Centers

    Science.gov (United States)

    Megies, T.; Barsch, R.; Beyreuther, M.; Krischer, L.; Wassermann, J.

    2012-04-01

    Python combines the possibilities of a full-blown programming language with the flexibility of an interactive scripting language. Its extensive standard library and many freely available high quality scientific modules cover most needs in developing scientific processing workflows. ObsPy extends Python's capabilities to fit the specific needs that arise when working with seismological data. It a) comes with a continuously growing signal processing toolbox that covers the most common tasks in seismological analysis, b) provides read and write support for many common waveform and metadata file formats and c) enables access to various data centers, webservices and databases to retrieve waveform data and station/event metadata. In combination with widely used, free Python packages like NumPy, SciPy, Matplotlib, IPython and PyQt, ObsPy makes it possible to develop complete workflows in Python, ranging from reading locally stored data or requesting data from one or more different data centers via signal analysis and data processing to visualization in GUI applications, output of modified/derived data and creating publication-quality figures. All functionality is extensively documented and the ObsPy Gallery/Tutorial give a good impression of the wide range of use cases. ObsPy is tested and running on Linux, MacOSX and Windows XP/Vista/7 and comes with installation routines for these systems. ObsPy is developed in a test-driven approach and is available under the GPL/LGPLv3 licences. Users are welcome to request help, report bugs or propose enhancements via the user mailing list or the Trac ticket system.

  19. ObsPy: A Python Toolbox for Seismology - Recent Developments and Applications

    Science.gov (United States)

    Megies, T.; Krischer, L.; Barsch, R.; Sales de Andrade, E.; Beyreuther, M.

    2014-12-01

    ObsPy (http://www.obspy.org) is a community-driven, open-source project dedicated to building a bridge for seismology into the scientific Python ecosystem. It offersa) read and write support for essentially all commonly used waveform, station, and event metadata file formats with a unified interface,b) a comprehensive signal processing toolbox tuned to the needs of seismologists,c) integrated access to all large data centers, web services and databases, andd) convenient wrappers to legacy codes like libtau and evalresp.Python, currently the most popular language for teaching introductory computer science courses at top-ranked U.S. departments, is a full-blown programming language with the flexibility of an interactive scripting language. Its extensive standard library and large variety of freely available high quality scientific modules cover most needs in developing scientific processing workflows. Together with packages like NumPy, SciPy, Matplotlib, IPython, Pandas, lxml, and PyQt, ObsPy enables the construction of complete workflows in Python. These vary from reading locally stored data or requesting data from one or more different data centers through to signal analysis and data processing and on to visualizations in GUI and web applications, output of modified/derived data and the creation of publication-quality figures.ObsPy enjoys a large world-wide rate of adoption in the community. Applications successfully using it include time-dependent and rotational seismology, big data processing, event relocations, and synthetic studies about attenuation kernels and full-waveform inversions to name a few examples. All functionality is extensively documented and the ObsPy tutorial and gallery give a good impression of the wide range of possible use cases.We will present the basic features of ObsPy, new developments and applications, and a roadmap for the near future and discuss the sustainability of our open-source development model.

  20. Pharmacologie de la morphine chez les sujets obèses avant et après chirurgie de l'obésité

    OpenAIRE

    Lloret Linares, Célia,

    2013-01-01

    In this thesis, we show that obesity is a factor of pharmacodynamic and pharmacokinetic morphine variability. In particular, absorption and exposure to oral morphine increases significantly after gastric bypass surgery . We demonstrate the role of enterocyte content of efflux transporter P-gp in determining the absorption and exposure to morphine.; Au cours de cette thèse, nous montrons que l’obésité est un facteur de variabilité pharmacodynamique et pharmacocinétique de la morphine. En parti...

  1. Determination of Optimum Cutting Parameters for Surface Roughness in Turning AL-B4C Composites

    Science.gov (United States)

    Channabasavaraja, H. K.; Nagaraj, P. M.; Srinivasan, D.

    2016-09-01

    Many materials such as alloys, composites find their applications on the basis of machinability, cost and availability. In the present work, machinability of Aluminium 1100 and Boron carbide (AL+ B4C) composite material is examined by using lathe tool dynometers (BANKA Lathe) by varying the cutting parameters like spindle speed, Depth of cut and Feed rate in 3 levels. Also, surface roughness is measured against the weight % of reinforcement in the composite (0, 4 and 8 %). From the study it is observed that the hardness of a composite material increases with increase in weight % of reinforcement material (B4C) by 26.27 and 66.7 % respectively. The addition of reinforcement materials influences the machinability. The cutting force in both X and Z direction were also found increment with the reinforcement percentage.

  2. Chemical compatibility of sodium exposed alloy D9 with B4C

    International Nuclear Information System (INIS)

    The control rods in India's first prototype fast breeder reactor (PFBR) would consist of high-density B4C (containing 67% 10B isotope) pellets enclosed in alloy D9 clad tubes. Enriched boron carbide required for control rod applications in PFBR is being produced indigenously by reacting elemental boron with graphite at high temperatures. The gap between the control rod material and the clad is filled with liquid sodium as the pins are of vented type. At the reactor operating temperatures of 773-873 K, the chemical interaction between B4C and D9 clad material surface modified by liquid sodium needs to be investigated and understood. Towards this, out-of-pile accelerated chemical compatibility experiments were carried out and the SEM/EDS, XRD and XPS results of the studies carried out at 973 K for 5000 h are presented in this paper

  3. Radio structures of a complete sample of quasars from the 4C catalog

    International Nuclear Information System (INIS)

    Radio observations are reported for 57 quasars. Included are all of the quasars of Schmidt's 1974 complete sample from the 4C catalog. The observations were made with the Green Bank interferometer at 2.7 and 8.1 GHz, with baselines ranging from 300 m to 35 km. Model brightness distributions are presented, consisting of one to four elliptical Gaussian components. Angular sizes range from <0.2 to 77 arcsec. Of 38 well-resolved sources 21 contain a compact central component coincident with the optical object. The quasar 4C32. 69=2349+328 appears to exhibit a jetlike structure connecting the central component to one of the outer lobes

  4. Synthesis and characterization of LiFePO4/C composite used as lithium storage electrodes

    Institute of Scientific and Technical Information of China (English)

    胡国荣; 张新龙; 彭忠东; 廖刚; 禹筱元

    2004-01-01

    LiFePO4/C composites with good rate capability and high energy density were prepared by adding sugar to the synthetic precursor. A significant improvement in electrode performance was achieved. The resulting carbon contents in the sample 1 and sample 2 are 3.06% and 4.95% (mass fraction), respectively. It is believed that the synthesis of LiFePO4 with sugar added before heating is a good method because the synthesized particles having uniform small size are covered by carbon. The performance of the cathodes was evaluated using coin cells. The samples were characterized by X-ray diffraction and scanning electron microscope observation. The addition of carbon limits the particles size growth and enables high electron conductivity. The LiFePO4/C composites show very good electrochemical performance delivering about 142 mAh/g specific capacity when being cycled at the C/10 rate. The capacity fade upon cycling is very small.

  5. Reaction behavior between B4C, 304 grade of stainless steel and Zircaloy at 1473 K

    Science.gov (United States)

    Sasaki, Ryosuke; Ueda, Shigeru; Kim, Sun-Joong; Gao, Xu; Kitamura, Shin-ya

    2016-08-01

    For a better understanding of the decommissioning of the Fukushima-daiichi nuclear power plant, the melting behavior of the control blade and the channel box should be clarified. In Fukushima nuclear reactor, the channel box was made of Zircaloy-4, and the control rode is made of B4C together with stainless steel cladding and sheath. In the study, the interaction among B4C, stainless steel (SUS), and Zircaloy-4 was investigated at 1473 K in either argon or air atmosphere. In argon, Zircaloy is melted by the diffusion of elements from SUS, and SUS was melted at 1473 K by the diffusion of C and B. In air, SUS reacted with B2O3 and formed an oxides melt firstly. Then, the oxidized Zircaloy contacted with this melt and fused. Moreover, the progress of core melting process during severe accident under different atmospheres was firstly discussed.

  6. Consolidation of B4C-TaB2 eutectic composites by spark plasma sintering

    OpenAIRE

    Dmytro Demirskyi

    2015-01-01

    The in situ synthesis/consolidation of B4C-TaB2 eutectic composites by spark plasma sintering (SPS) is reported. The microstructure–property relations were determined for composites with the B4C-TaB2 eutectic composition as functions of TaB2 content, and TaB2-TaB2 interlamellar spacing. A clear maximum in fracture toughness was identified (∼4.5 MPa m1/2) for eutectic composites with interlamellar spacing between 0.9 and 1.1 μm. The composites with the hypereutectic composition of 40 mol.% TaB...

  7. Cr/B4C multilayer mirrors: Study of interfaces and X-ray reflectance

    Science.gov (United States)

    Burcklen, C.; Soufli, R.; Dennetiere, D.; Polack, F.; Capitanio, B.; Gullikson, E.; Meltchakov, E.; Thomasset, M.; Jérome, A.; de Rossi, S.; Delmotte, F.

    2016-03-01

    We present an experimental study of the effect of layer interfaces on the x-ray reflectance in Cr/B4C multilayer interference coatings with layer thicknesses ranging from 0.7 nm to 5.4 nm. The multilayers were deposited by magnetron sputtering and by ion beam sputtering. Grazing incidence x-ray reflectometry, soft x-ray reflectometry, and transmission electron microscopy reveal asymmetric multilayer structures with a larger B4C-on-Cr interface, which we modeled with a 1-1.5 nm thick interfacial layer. Reflectance measurements in the vicinity of the Cr L2,3 absorption edge demonstrate fine structure that is not predicted by simulations using the currently tabulated refractive index (optical constants) values for Cr.

  8. Characterization of Al–Al{sub 4}C{sub 3} nanocomposites produced by mechanical milling

    Energy Technology Data Exchange (ETDEWEB)

    Santos-Beltrán, A., E-mail: asantos@utchsur.edu.mx [Universidad Tecnológica de Chihuahua Sur, Carr. Chihuahua a Aldama km. 3 S/N, Col. Colinas del León, CP. 31313 Chihuahua, Chih. (Mexico); Goytia-Reyes, R. [Centro de Investigación en Materiales Avanzados (CIMAV), Laboratorio Nacional de Nanotecnología, Miguel de Cervantes No. 120, C.P. 31109 Chihuahua, Chih. (Mexico); Morales-Rodriguez, H.; Gallegos-Orozco, V. [Universidad Tecnológica de Chihuahua Sur, Carr. Chihuahua a Aldama km. 3 S/N, Col. Colinas del León, CP. 31313 Chihuahua, Chih. (Mexico); Santos-Beltrán, M. [Centro de Investigación en Materiales Avanzados (CIMAV), Laboratorio Nacional de Nanotecnología, Miguel de Cervantes No. 120, C.P. 31109 Chihuahua, Chih. (Mexico); Baldenebro-Lopez, F. [Universidad Tecnológica de Chihuahua Sur, Carr. Chihuahua a Aldama km. 3 S/N, Col. Colinas del León, CP. 31313 Chihuahua, Chih. (Mexico); Martínez-Sánchez, R. [Centro de Investigación en Materiales Avanzados (CIMAV), Laboratorio Nacional de Nanotecnología, Miguel de Cervantes No. 120, C.P. 31109 Chihuahua, Chih. (Mexico)

    2015-08-15

    In this work, a mixture of Al–C–Al{sub 4}C{sub 3} nanopowder previously synthesized by mechanical milling and subsequent thermal treatment was used to reinforce the Al matrix. The nanocomposites were fabricated via high-energy ball milling and subsequent sintering process for different periods of time at 550 °C. Hardness and compression tests were performed to evaluate the mechanical properties of the nanocomposites in the as-milled and sintered conditions. According to the results the reinforcement located in the grain boundaries is responsible for the brittle behavior observed in the nanocomposites during the compression test. The combined effect of sintering and precipitation mechanisms produced an evident increase of the strength of the Al matrix at a relatively short sintering time. By using the Rietveld method the crystallite size and microstrain measurements were determined and correlated with the microhardness values. For the proper characterization of the nanoparticles present in the Al matrix, atomic force microscopy and high resolution electron microscopy were used. - Highlights: • Nanostructured Al{sub 4}C{sub 3} reinforcement was fabricated via mechanical milling and heat treatment. • We found a significant increase of the mechanical properties at short sintering times. • The formation of Al{sub 4}C{sub 3} with during sintering time restricted the excessive growth of the crystallite. • Al{sub 4}C{sub 3} located in the grain boundaries causes brittle fracture observed in compression tests. • There is a correlation between, crystallite size and microstrain values with microhardness.

  9. AGILE detection of enhanced gamma-ray emission from the FSRQ 4C +01.02

    Science.gov (United States)

    Verrecchia, F.; Lucarelli, F.; Pittori, C.; Bulgarelli, A.; Tavani, M.; Fioretti, V.; Zoli, A.; Piano, G.; Striani, E.; Vercellone, S.; Donnarumma, I.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Parmiggiani, N.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    2016-07-01

    AGILE is detecting increased gamma-ray emission above 100 MeV from a position consistent with the flat spectrum radio quasar 4C +01.02 (also known as 5BZQ J0108+0135, PKS 0106+01 and 3FGL J0108.7+0134), recently reported in flaring activity also by Fermi/LAT during the week Jun 6-12 (http://fermisky.blogspot.it).

  10. FY-3A Launched Atop A LM-4C Launch Vehicle

    Institute of Scientific and Technical Information of China (English)

    Rain.L

    2008-01-01

    @@ FY-3A,the first satellite of China's new generation of polar-orbiting meteorological satellites,was launched into space atop a modified LM-4C launch vehicle.The satellite separated from the rocket 19 minutes after the takeoff.Flying at an altitude of 807km with an inclination of 98.8 degrees,the satellite circles in polar orbit 14 times everyday,covering the whole globe twice a day.

  11. M4C9 +(M = Ti, V): New gas phase clusters

    Indian Academy of Sciences (India)

    R Selvan; L Gowrishankar; T Pradeep

    2001-10-01

    New metal-carbon clusters, M4C9 +(M = Ti, V), generated using a combined thermal arc discharge evaporation set-up, have been studied with quadrupole mass spectrometry. Reactivities of these clusters have been investigated by means of association reactions with H2O. Metal-carbon clusters of other compositions have also been studied. We speculate on the mechanism of formation of larger metal-carbon clusters.

  12. Effect of different carbon precursors on properties of LiFePO4/C

    Institute of Scientific and Technical Information of China (English)

    肖政伟; 张英杰; 胡国荣

    2015-01-01

    The anoxic decomposition and influence of carbon precursors on the properties of LiFePO4/C prepared by using Fe2O3 were investigated. X-ray powder diffractometry, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and carbon content and charge–discharge tests were applied to the characterization of the as-synthesized cathodes. Partial carbon is lost in the anaerobic decomposition of organic precursors and a high hydrogen content leads to a high residual carbon rate. Pyromellitic anhydride and citric acid participate in reactions before and in ball-milling. All the chosen carbon precursors are capable of producing LiFePO4 with high degree of crystallinity and purity. The carbon derived fromα-D-glucose, pyromellitic anhydride, soluble starch, citric acid and polyacrylamide has a loose and porous texture in LiFePO4/C which forms conduction on and between LiFePO4 particles. LiFePO4/C prepared by usingα-D-glucose, pyromellitic anhydride, citric acid and sucrose exhibits appreciable electrochemical performance. Graphite alone is able to enhance the electrochemical performance of LiFePO4 to a limited extent but incapable of preparing practical cathode.

  13. Structural modifications induced by ion irradiation and temperature in boron carbide B4C

    Science.gov (United States)

    Victor, G.; Pipon, Y.; Bérerd, N.; Toulhoat, N.; Moncoffre, N.; Djourelov, N.; Miro, S.; Baillet, J.; Pradeilles, N.; Rapaud, O.; Maître, A.; Gosset, D.

    2015-12-01

    Already used as neutron absorber in the current French nuclear reactors, boron carbide (B4C) is also considered in the future Sodium Fast Reactors of the next generation (Gen IV). Due to severe irradiation conditions occurring in these reactors, it is of primary importance that this material presents a high structural resistance under irradiation, both in the ballistic and electronic damage regimes. Previous works have shown an important structural resistance of boron carbide even at high neutron fluences. Nevertheless, the structural modification mechanisms due to irradiation are not well understood. Therefore the aim of this paper is to study structural modifications induced in B4C samples in different damage regimes. The boron carbide pellets were shaped and sintered by using spark plasma sintering method. They were then irradiated in several conditions at room temperature or 800 °C, either by favoring the creation of ballistic damage (between 1 and 3 dpa), or by favoring the electronic excitations using 100 MeV swift iodine ions (Se ≈ 15 keV/nm). Ex situ micro-Raman spectroscopy and Doppler broadening of annihilation radiation technique with variable energy slow positrons were coupled to follow the evolution of the B4C structure under irradiation.

  14. Laser controlled melting of HSLA steel surface with presence of B{sub 4}C particles

    Energy Technology Data Exchange (ETDEWEB)

    Yilbas, B.S., E-mail: bsyilbas@kfupm.edu.sa [ME Department, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia); Patel, F., E-mail: faheemmp@kfupm.edu.sa [ME Department, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia); Karatas, C., E-mail: doc_cihan@hotmail.com [Engineering College, Hacettepe University (Turkey)

    2013-10-01

    Laser gas assisted melting of high strength low alloy steel surface is carried out. The alloy surface is pre-prepared to contain 5% B{sub 4}C particles in a 40 μm thick carbon film prior to laser treatment process. Metallurgical and morphological changes in the laser treated layer are examined by using scanning electron microscopy, energy dispersive spectroscopy, and X-ray diffraction. The residual stress developed and the microhardness of the resulting surface is measured. It is found that B{sub 4}C particles remain in solid phase in the surface region due to their high melting temperature. The dense layer consisting of fine grains are formed at the surface and the feathery like structure is observed below the surface vicinity, which consists of martensite and nitride precipitations. The use of nitrogen at high pressure causes the formation of nitride compounds at the surface, which contributes to the volume shrinkage in the dense layer. Surface microhardness increases considerably because of attainment of high cooling rates, formation of nitride compounds, and presence of B{sub 4}C particles at the surface. .

  15. Laser controlled melting of HSLA steel surface with presence of B4C particles

    Science.gov (United States)

    Yilbas, B. S.; Patel, F.; Karatas, C.

    2013-10-01

    Laser gas assisted melting of high strength low alloy steel surface is carried out. The alloy surface is pre-prepared to contain 5% B4C particles in a 40 μm thick carbon film prior to laser treatment process. Metallurgical and morphological changes in the laser treated layer are examined by using scanning electron microscopy, energy dispersive spectroscopy, and X-ray diffraction. The residual stress developed and the microhardness of the resulting surface is measured. It is found that B4C particles remain in solid phase in the surface region due to their high melting temperature. The dense layer consisting of fine grains are formed at the surface and the feathery like structure is observed below the surface vicinity, which consists of martensite and nitride precipitations. The use of nitrogen at high pressure causes the formation of nitride compounds at the surface, which contributes to the volume shrinkage in the dense layer. Surface microhardness increases considerably because of attainment of high cooling rates, formation of nitride compounds, and presence of B4C particles at the surface.

  16. Location of gamma-ray flaring region in quasar 4C +21.35

    CERN Document Server

    Lei, Maichang

    2015-01-01

    4C +21.35 is a flat-spectrum-radio-quasar-type blazar, in which the rapid variability of very high energy (VHE, $E_{\\gamma}\\gtrsim 100$\\,GeV) emission as short as $\\sim$ 10 minutes was observed by MAGIC Cherenkov telescopes, and the VHE spectrum extends up to at least 400\\,GeV. In this paper, by using a flat broad-line region (BLR) structure, we study the location and properties of $\\gamma$-ray emitting region of 4C +21.35 under the constraints of multiwavelength data. We fit three quasi-simultaneous spectral energy distributions (SEDs) using homogeneous one-zone leptonic model, in which the flat BLR with the aperture angle of $\\alpha=25^{\\circ}$ and a spherically symmetric hot dusty torus with the temperature of $T_{\\rm sub}=1200$\\,K, are assumed. The results show that the jet structure of 4C +21.35 is nearly conical with a half-opening angle of $\\theta_{\\rm j}\\simeq 0.29^{\\circ}-0.6^{\\circ}$. Furthermore, the emitting region is located within the BLR clouds and approaches to outer radius of the BLR during t...

  17. Preparation and investigation of Al–4 wt% B4C nanocomposite powders using mechanical milling

    Indian Academy of Sciences (India)

    A Alizadeh; E Taheri-Nassaj; H R Baharvandi

    2011-08-01

    Boron carbide nanoparticles were produced using commercially available boron carbide powder (0.8 m).Mechanical milling was used to synthesize Al nanostructured powder in a planetary ball-mill under argon atmosphere up to 20 h. The same process was applied for Al–4 wt% B4C nanocomposite powders to explore the role of nanosize reinforcements on mechanical milling stages. Scanning electron microscopy (SEM) analysis as well as apparent density measurements were used to optimize the milling time needed for completion of the mechanical milling process. The results show that the addition of boron carbide particles accelerate the milling process, leading to a faster work hardening rate and fracture of aluminum matrix. FE-SEM images show that distribution of boron carbide particles in aluminum matrix reaches a full homogeneity when steady state takes place. The better distribution of reinforcement throughout the matrix would increase hardness of the powder. To study the compressibility of milled powder, modified heckel equation was used to consider the pressure effect on yield strength as well as reinforcing role of B4C particles. For better distribution of reinforcement throughout the matrix, , modified heckel equation was used to consider the pressure effect on yield strength as well as reinforcing role of B4C particles.

  18. AGN feedback and iron enrichment in the powerful radio galaxy, 4C+55.16

    CERN Document Server

    Hlavacek-Larrondo, J; Sanders, J S; Taylor, G B

    2011-01-01

    We present a detailed X-ray analysis of 4C+55.16, an unusual and interesting radio galaxy, located at the centre of a cool core cluster of galaxies. 4C+55.16 is X-ray bright (~10^45 erg/s), radio powerful, and shows clear signs of interaction with the surrounding intracluster medium. By combining deep Chandra (100 ks) with 1.4 GHz VLA observations, we find evidence of multiple outbursts from the central AGN, providing enough energy to offset cooling of the ICM (P_bubbles=6.7x10^44 erg/s). Furthermore, 4C+55.16 has an unusual intracluster iron distribution showing a plume-like feature rich in Fe L emission that seems to run along one of the X-ray cavities. The excess of Fe associated with the plume is around 10^7M_sol. The metal abundances are consistent with being Solar-like, indicating that both SNIa and SNII contribute to the enrichment. The plume and southern cavity form a region of cool metal-rich gas. At the edge of this region, there is a clear discontinuity in temperature (from kT~2.5 keV to kT~5.0 keV...

  19. Evolution of reinforcement distribution in Al-B4C composites during accumulative roll bonding

    International Nuclear Information System (INIS)

    Highlights: → ARB developed a nanostructure in the matrix of the Al-B4C composite. → An improvement in the reinforcement distribution was found by increasing ARB passes. → By progression of ARB from one to seven passes, hardness increased from 60 to 82 HV. -- Abstract: The distribution of reinforcement particles in the matrix of a composite is one of the most important microstructural features affecting properties. In this study, nanostructured Al-B4C composite sheets were processed by accumulative roll bonding (ARB), and the effect of the number of ARB cycles on the distribution of the B4C particles in the Al matrix was evaluated. From optical microscopic studies accompanied by the radial distribution function analysis, it was realized that the microstructure uniformity is improved by increasing the number of ARB cycles. It was in good agreement with bulk hardness measurements in which the standard deviation of the hardness values was decreased by progression of the ARB process. In addition, the X-ray diffraction peak profile analysis revealed that the area weighted mean crystallite size of the Al matrix decreases to the nanometric scale (114 nm) after seven ARB cycles.

  20. VizieR Online Data Catalog: RVs & V-band LCs of probable members of Cyg OB2 (Kiminki+, 2015)

    Science.gov (United States)

    Kiminki, D. C.; Kobulnicky, H. A.; Vargas Alvarez, C. A.; Alexander, M. J.; Lundquist, M. J.

    2016-01-01

    Optical spectroscopic observations of the four targets were obtained as part of the Cygnus OB2 Radial Velocity Survey on numerous dates between 2001 and 2011 using a variety of telescopes and instruments as described in Papers I-IV (see References section below) of this series. Several additional observations were obtained in 2012 October (on MT91 696 and Schulte 3) and 2013 May-June (on MT91 372) using the Wyoming Infrared Observatory (WIRO). Photometry of MT91 696 was obtained on nine nights between 2012 October 17 and November 10 at the University of Wyoming 0.6m Red Buttes Observatory (RBO). Data on Schulte 3 was obtained on 14 nights at RBO between 2012 October 17 and December 21, and data on CPR2002 A36 was obtained on four nights between 2012 December 10 and 22. Photometry of MT91 372 was also obtained at RBO on seven nights between 2013 June 14 and July 8. (6 data files).

  1. An eclipsing double-line spectroscopic binary at the stellar/substellar boundary in the Upper Scorpius OB association

    CERN Document Server

    Lodieu, N; Hernandez, J I Gonzalez; Sanchis-Ojeda, R; Narita, N; Kawashima, Y; Kawauchi, K; Mascareño, A Suarez; Deeg, H; Arranz, J Prieto; Rebolo, R; Palle, E; Bejar, V J S; Ferragamo, A; Rubiño-Martin, J A

    2015-01-01

    We aim at constraining evolutionary models at low mass and young ages by identifying interesting transiting system members of the nearest OB association to the Sun, Upper Scorpius, targeted by the Kepler mission. We produced light curves for M dwarf members of the USco region surveyed during the second campaign of the Kepler K2 mission. We identified 'by eye' a transiting system, UScoJ161630.68-251220.1 (=EPIC203710387) with a combined spectral type of M5.25 whose photometric, astrometric, and spectroscopic properties makes it a member of USco. We conducted an extensive photometric and spectroscopic follow-up of this transiting system with a suite of telescopes and instruments to characterise the properties of each component of the system. We calculated a transit duration of about 2.42 hours occuring every 2.88 days with a slight difference in transit depth and phase between the two components. We estimated a mass ratio of 0.922+/-0.015 from the semi-amplitudes of the radial velocity curves for each component...

  2. Preparation and characterization of B4C coatings for advanced research light sources.

    Science.gov (United States)

    Störmer, Michael; Siewert, Frank; Sinn, Harald

    2016-01-01

    X-ray optical elements are required for beam transport at the current and upcoming free-electron lasers and synchrotron sources. An X-ray mirror is a combination of a substrate and a coating. The demand for large mirrors with single layers consisting of light or heavy elements has increased during the last few decades; surface finishing technology is currently able to process mirror lengths up to 1 m with microroughness at the sub-nanometre level. Additionally, thin-film fabrication is able to deposit a suitable single-layer material, such as boron carbide (B4C), some tens of nanometres thick. After deposition, the mirror should provide excellent X-ray optical properties with respect to coating thickness errors, microroughness values and slope errors; thereby enabling the mirror to transport the X-ray beam with high reflectivity, high beam flux and an undistorted wavefront to an experimental station. At the European XFEL, the technical specifications of the future mirrors are extraordinarily challenging. The acceptable shape error of the mirrors is below 2 nm along the whole length of 1 m. At the Helmholtz-Zentrum Geesthacht (HZG), amorphous layers of boron carbide with thicknesses in the range 30-60 nm were fabricated using the HZG sputtering facility, which is able to cover areas up to 1500 mm long by 120 mm wide in one step using rectangular B4C sputtering targets. The available deposition area is suitable for the specified X-ray mirror dimensions of upcoming advanced research light sources such as the European XFEL. The coatings produced were investigated by means of X-ray reflectometry and interference microscopy. The experimental results for the B4C layers are discussed according to thickness uniformity, density, microroughness and thermal stability. The variation of layer thickness in the tangential and sagittal directions was investigated in order to estimate the achieved level of uniformity over the whole deposition area, which is considerably

  3. Preparation and characterization of B4C coatings for advanced research light sources

    Science.gov (United States)

    Störmer, Michael; Siewert, Frank; Sinn, Harald

    2016-01-01

    X-ray optical elements are required for beam transport at the current and upcoming free-electron lasers and synchrotron sources. An X-ray mirror is a combination of a substrate and a coating. The demand for large mirrors with single layers consisting of light or heavy elements has increased during the last few decades; surface finishing technology is currently able to process mirror lengths up to 1 m with microroughness at the sub-nanometre level. Additionally, thin-film fabrication is able to deposit a suitable single-layer material, such as boron carbide (B4C), some tens of nanometres thick. After deposition, the mirror should provide excellent X-ray optical properties with respect to coating thickness errors, microroughness values and slope errors; thereby enabling the mirror to transport the X-ray beam with high reflectivity, high beam flux and an undistorted wavefront to an experimental station. At the European XFEL, the technical specifications of the future mirrors are extraordinarily challenging. The acceptable shape error of the mirrors is below 2 nm along the whole length of 1 m. At the Helmholtz-Zentrum Geesthacht (HZG), amorphous layers of boron carbide with thicknesses in the range 30–60 nm were fabricated using the HZG sputtering facility, which is able to cover areas up to 1500 mm long by 120 mm wide in one step using rectangular B4C sputtering targets. The available deposition area is suitable for the specified X-ray mirror dimensions of upcoming advanced research light sources such as the European XFEL. The coatings produced were investigated by means of X-ray reflectometry and interference microscopy. The experimental results for the B4C layers are discussed according to thickness uniformity, density, microroughness and thermal stability. The variation of layer thickness in the tangential and sagittal directions was investigated in order to estimate the achieved level of uniformity over the whole deposition area, which is

  4. On acoustic waveform tomography of wide-angle OBS data—strategies for pre-conditioning and inversion

    Science.gov (United States)

    Kamei, R.; Pratt, R. G.; Tsuji, T.

    2013-08-01

    We successfully apply the acoustic Laplace-Fourier waveform tomography method to delineate P-wave velocity structures of the mega-splay fault system in the central part of the seismogenic Nankai subduction zone offshore Japan, using densely sampled wide-angle ocean bottom seismograph (OBS) data originally acquired in 2004. Our success is due to new and carefully designed data preconditioning and inversion strategies to mitigate (i) the well-known non-linearity of waveform inversion, (ii) the challenges arising from crustal-scale survey designs (e.g. undersampling of the OBSs), and (iii) modelling errors due to the use of the acoustic assumption. We identify a sixfold set of key components that together lead to the success of the high-resolution waveform tomography image: (i) Availability of low-frequency components (starting at 2.25 Hz) reducing the non-linearity, and access to large offset data (up to 55 km) increasing the depth of illumination and the recovery of low wavenumber components. (ii) A highly accurate traveltime tomography result (with an rms error of approximately 60 ms) that further mitigates the non-linearity. (iii) A hierarchical inversion approach in which phase spectra are inverted first to reduce artefacts from the acoustic assumption, and amplitude information is only incorporated in the final stages. (iv) A Laplace-Fourier domain approach that facilitates a multiscale approach to mitigate non-linearity by restricting the inversion to the low frequency components and early arrivals first, and sequentially including higher frequencies and later arrivals. (v) A pre-conditioning strategy for eliminating undesirable high wavenumber components from the the gradient. (vi) A strategy for source estimation that reduce the influence of the instrumental design. In the OBS case study used for illustration purposes, Laplace-Fourier waveform tomography retrieves velocity anomalies as small as 700 m (horizontally) and 350 m (vertically) above the top of the

  5. Multifunctional Bi2ZnOB2O6 single crystals for second and third order nonlinear optical applications

    Science.gov (United States)

    Iliopoulos, K.; Kasprowicz, D.; Majchrowski, A.; Michalski, E.; Gindre, D.; Sahraoui, B.

    2013-12-01

    Bi2ZnOB2O6 nonlinear optical single crystals were grown by means of the Kyropoulos method from stoichiometric melt. The second and third harmonic generation (SHG/THG) of Bi2ZnOB2O6 crystals were investigated by the SHG/THG Maker fringes technique. Moreover, SHG microscopy studies were carried out providing two-dimensional SHG images as a function of the incident laser polarization. The high nonlinear optical efficiency combined with the possibility to grow high quality crystals make Bi2ZnOB2O6 an excellent candidate for photonic applications.

  6. Proposal of a multi-layer network architecture for OBS/GMPLS network interworking

    Science.gov (United States)

    Guo, Hongxiang; Tsuritani, Takehiro; Yin, Yawei; Otani, Tomohiro; Wu, Jian

    2007-11-01

    In order to enable the existing optical circuit switching (OCS) network to support both wavelength and subwavelength granularities, this paper proposes overlay-based multi-layer network architecture for interworking the generalized multi-protocol label switching (GMPLS) controlled OCS network with optical burst switching (OBS) networks. A dedicated GMPLS border controller with necessary GMPLS extensions, including group label switching path (LSP) provisioning, node capability advertisement, and standard wavelength label as well as wavelength availability advertisement, is introduced in this multi-layer network to enable a simple but flexible interworking operation. The feasibility of this proposal is experimentally confirmed by demonstrating an OBS/GMPLS testbed, in which the extended node capability advertisement and group LSP functions successfully enabled the burst header packet (BHP) and data burst (DB) to transmit over a GMPLS-controlled transparent OCS network.

  7. Wavelength assignment algorithm considering the state of neighborhood links for OBS networks

    Science.gov (United States)

    Tanaka, Yu; Hirota, Yusuke; Tode, Hideki; Murakami, Koso

    2005-10-01

    Recently, Optical WDM technology is introduced into backbone networks. On the other hand, as the future optical switching scheme, Optical Burst Switching (OBS) systems become a realistic solution. OBS systems do not consider buffering in intermediate nodes. Thus, it is an important issue to avoid overlapping wavelength reservation between partially interfered paths. To solve this problem, so far, the wavelength assignment scheme which has priority management tables has been proposed. This method achieves the reduction of burst blocking probability. However, this priority management table requires huge memory space. In this paper, we propose a wavelength assignment algorithm that reduces both the number of priority management tables and burst blocking probability. To reduce priority management tables, we allocate and manage them for each link. To reduce burst blocking probability, our method announces information about the change of their priorities to intermediate nodes. We evaluate its performance in terms of the burst blocking probability and the reduction rate of priority management tables.

  8. Ara OB1 - A stellar association formed by the action of an energetic event?

    Science.gov (United States)

    Arnal, E. M.; Cersosimo, J. C.; May, J.; Bronfman, L.

    1987-01-01

    Neutral hydrogen (at the wavelength of 21 cm) and carbon monoxide (at 2.6 mm) line observations of the interstellar medium in the neighborhood of the association Ara OB1 are reported. The observed H I distribution indicates the presence of an expanding structure. The total H I mass associated with such feature amounts to 4800 solar masses, and its momentum and kinetic energy are about 40,000 solar mass km/s and 3 x 10 to the 48th erg, respectively. The H I structure, 42 pc in diameter, expands at a speed of 10 km/s. A possible origin for the expanding H I structure, and a genetic link between such structure and Ara OB1 are proposed.

  9. Batch conversion of methane to methanol using Methylosinus trichosporium OB3b as biocatalyst.

    Science.gov (United States)

    Hwang, In Yeub; Hur, Dong Hoon; Lee, Jae Hoon; Park, Chang-Ho; Chang, In Seop; Lee, Jin Won; Lee, Eun Yeol

    2015-03-01

    Recently, methane has attracted much attention as an alternative carbon feedstock since it is the major component of abundant shale and natural gas. In this work, we produced methanol from methane using whole cells of Methylosinus trichosporium OB3b as the biocatalyst. M. trichosporium OB3b was cultured on NMS medium with a supply of 7:3 air/methane ratio at 30°C. The optimal concentrations of various methanol dehydrogenase inhibitors such as potassium phosphate and EDTA were determined to be 100 and 0.5 mM, respectively, for an efficient production of methanol. Sodium formate (40 mM) as a reducing power source was added to enhance the conversion efficiency. A productivity of 49.0 mg/l·h, titer of 0.393 g methanol/l, and conversion of 73.8% (mol methanol/mol methane) were obtained under the optimized batch condition. PMID:25563419

  10. High-mass x-ray binaries and ob runaway stars

    Directory of Open Access Journals (Sweden)

    L. Kaper

    2004-01-01

    Full Text Available Las binarias masivas de rayos X (HMXBs representan una fase evolutiva importante, y proporcionan infor- maci on sobre las propiedades de las primarias OB y de las secundarias compactas (estrellas de neutrones, agujeros negros. Observaciones recientes indican que las estrellas de neutrones en algunos sistemas (Vela X-1, 4U 1700-37 tienen masas mayores que la masa can onica 1.35 M . Estas observaciones tienen consecuencias importantes para la ecuaci on de estado a densidades supranucleares y para la formaci on de estrellas de neu- trones y agujeros negros (supernovas y estallidos de rayos gama. A consecuencia de la explosi on de supernova que produjo el objeto compacto, las HMXBs tienen velocidades espaciales altas, y son desbocadas. Alter- nativamente, las desbocadas OB pueden ser expelidas de un c umulo mediante interacciones din amicas. Las observaciones del Hipparcos indican que ambos mecanismos entran en juego.

  11. Influence on spacecraft control systems of evolving O/B technology and standards

    Science.gov (United States)

    Creasey, Richard

    1990-10-01

    Analysis of the operation requirements of future spacecraft show that past approaches are not sufficient. The use of on board (O/B) technology and the development of the specific standards are proposed in order to meet those increasing requirements. The increase in on board decision making capability in spacecraft is discussed. Standardization of spacecraft operations and the impact on present and future ESA standards by this trend are considered.

  12. Detoxification of Mercury by Methanobactin from Methylosinus trichosporium OB3b

    OpenAIRE

    Vorobev, Alexey; Jagadevan, Sheeja; Baral, Bipin S.; DiSpirito, Alan A.; Freemeier, Brittani C.; Bergman, Brandt H.; Bandow, Nathan L.; Semrau, Jeremy D.

    2013-01-01

    Many methanotrophs have been shown to synthesize methanobactin, a novel biogenic copper-chelating agent or chalkophore. Methanobactin binds copper via two heterocyclic rings with associated enethiol groups. The structure of methanobactin suggests that it can bind other metals, including mercury. Here we report that methanobactin from Methylosinus trichosporium OB3b does indeed bind mercury when added as HgCl2 and, in doing so, reduced toxicity associated with Hg(II) for both Alphaproteobacter...

  13. Degradation of Trichloroethylene by Methanol-Grown Cultures of Methylosinus trichosporium OB3b PP358

    OpenAIRE

    Fitch, M. W.; Speitel, G. E.; Georgiou, G.

    1996-01-01

    A soluble methane monooxygenase-constitutive mutant strain of Methylosinus trichosporium OB3b, strain PP358, was grown with methanol as the carbon source, and the kinetics of trichloroethylene (TCE) degradation were determined. PP358 exhibited high TCE degradation rates under both oxygen- and carbon-limiting conditions. The optimal pseudo first-order rate constant for TCE was comparable to the values measured for cells grown with methane. We found that growth under oxygen-limiting conditions ...

  14. Kinetics of chlorinated hydrocarbon degradation by Methylosinus trichosporium OB3b and toxicity of trichloroethylene.

    OpenAIRE

    Oldenhuis, Roelof; Oedzes, Johannes Y.; Waarde, Jacob J. van der; Janssen, Dick B.

    1991-01-01

    The kinetics of the degradation of trichloroethylene (TCE) and seven other chlorinated aliphatic hydrocarbons by Methylosinus trichosporium OB3b were studied. All experiments were performed with cells grown under copper stress and thus expressing soluble methane monooxygenase. Compounds that were readily degraded included chloroform, trans-1,2-dichloroethylene, and TCE, with V(max) values of 550, 330, and 290 nmol min-1 mg of cells-1, respectively. 1,1-Dichloroethylene was a very poor substra...

  15. Identification of current attacks and their counter measures in Optical Burst Switched (OBS) network

    OpenAIRE

    Siddharth Singh Chouhan; Prof. Sanjay Sharma

    2012-01-01

    As day by day application grows internet requires large amount of bandwidth. Optical Burst Switching (OBS) is the next generation optical Internet with IP over WDM as the core architecture. It can achieve a balance between Optical Circuit Switching (OCS) and Optical Packet Switching (OPS). Optical network supports huge bandwidth and transmits data at an average rate of 50Tb/s. But we need to exploit the fiber’s huge bandwidth through WDM which is the current favorite multiplexing technology i...

  16. LOCALIZATION FEATURES OF GEOCHEMICAL TYPES OF UNDERGROUND WATER OF OB-TOMSKOYE INTERFLUVIAL

    Directory of Open Access Journals (Sweden)

    Yankovich E. P.

    2015-03-01

    Full Text Available The chemical composition of neogen-quaternary, paleogene, cretaceous and paleozoic aquifer systems in the Ob-Tomskoye interfluves area is presented in the article. The water saturation with respect to secondary minerals is described. Authors show that the waters of all studied aquifer systems are saturated with respect to montmorillonites and calcite in a less degree. The geochemical water types are identified and their distribution is described

  17. Hydraulic analysis of water supply system Šmartno ob Paki

    OpenAIRE

    Stropnik, Petra

    2006-01-01

    The subject of the Graduation Project is the hydraulics of the Šmartno ob Paki water supply system. The primary focus is on the analysis of pressure and flow conditions using the appropriate software tools, and the optimisation of the existing situation. The Graduation Project features a theoretical and a practical part. The theoretical part includes all the bases required for hydraulic modelling, and the calculations and analysis of hydraulic conditions, while the practical part involves the...

  18. ObStruct: a method to objectively analyse factors driving population structure using Bayesian ancestry profiles.

    Directory of Open Access Journals (Sweden)

    Velimir Gayevskiy

    Full Text Available Bayesian inference methods are extensively used to detect the presence of population structure given genetic data. The primary output of software implementing these methods are ancestry profiles of sampled individuals. While these profiles robustly partition the data into subgroups, currently there is no objective method to determine whether the fixed factor of interest (e.g. geographic origin correlates with inferred subgroups or not, and if so, which populations are driving this correlation. We present ObStruct, a novel tool to objectively analyse the nature of structure revealed in Bayesian ancestry profiles using established statistical methods. ObStruct evaluates the extent of structural similarity between sampled and inferred populations, tests the significance of population differentiation, provides information on the contribution of sampled and inferred populations to the observed structure and crucially determines whether the predetermined factor of interest correlates with inferred population structure. Analyses of simulated and experimental data highlight ObStruct's ability to objectively assess the nature of structure in populations. We show the method is capable of capturing an increase in the level of structure with increasing time since divergence between simulated populations. Further, we applied the method to a highly structured dataset of 1,484 humans from seven continents and a less structured dataset of 179 Saccharomyces cerevisiae from three regions in New Zealand. Our results show that ObStruct provides an objective metric to classify the degree, drivers and significance of inferred structure, as well as providing novel insights into the relationships between sampled populations, and adds a final step to the pipeline for population structure analyses.

  19. 基于四要素教学设计4C/ID模型初探

    Institute of Scientific and Technical Information of China (English)

    魏芸

    2012-01-01

    本文从四要素教学设计4C/ID模型的基本概念、原理出发,阐述了4C/ID模型的核心要素.4C/ID模型打破了传统学习方式,探讨了基于4C/ID模型的复杂学习任务架构的优势,对于提高终身学习、创新学习及促进技能方面的培养起到了积极作用.

  20. ObsPy – What can it do for data centers and observatories?

    Directory of Open Access Journals (Sweden)

    Joachim Wassermann

    2011-04-01

    Full Text Available Data acquisition by seismic centers relies on real-time systems, like SeisComP3, Antelope and Earthworm. However, these are complex systems that are designed for fast and precisely defined standard real-time analyses. Therefore, it is not a simple task to access or modify internal routines, and to integrate them into custom-processing workflows or to perform in-depth data analyses. Often a library is necessary that provides convenient access to data and allows easy control over all of the operations that are to be performed on the data. ObsPy is such a library, which is designed to access and process seismological waveform data and metadata. We use short and simple examples here to demonstrate how effective it is to use Python for seismological data analysis. Then, we illustrate the general capabilities of ObsPy, and highlight some of its specific aspects that are relevant for seismological data centers and observatories, through presentation of real-world examples. Finally, we demonstrate how the ObsPy library can be used to develop custom graphical user interface applications.

  1. On the nature of high reddening of Cygnus OB2 #12 hypergiant

    CERN Document Server

    Maryeva, O V; Goranskij, V P; Dyachenko, V V; Karpov, S V; Malogolovets, E V; Rastegaev, D A

    2016-01-01

    To explain the nature of the high reddening (Av~10 mag) towards one of the most luminous stars in the Galaxy - Cyg OB2 #12 (B5 Ia-0), also known as MT304, we carried out spectro-photometric observations of 24 stars located in its vicinity. We included five new B-stars among the members of Cygnus OB2, and for five more photometrically selected stars we spectroscopically confirmed their membership. We constructed the map of interstellar extinction within 2.5 arcmin radius and found that interstellar extinction increases towards MT304. According to our results the most reddened OB-stars in the association after MT304 are J203240.35+411420.1 and J203239.90+411436.2, located about 15 arcsec away from it. Interstellar extinction towards these stars is about 9 mag. The increase of reddening towards MT304 suggests that the reddening excess may be caused by the circumstellar shell ejected by the star during its evolution. This shell absorbs 1 mag, but its chemical composition and temperature are unclear. We also repor...

  2. Predicting Gaia's Parallax Distance to the Cygnus OB2 Association with Eclipsing Binaries

    CERN Document Server

    Kiminki, Daniel C; Álvarez, Carlos A Vargas; Alexander, Michael J; Lundquist, Michael J

    2015-01-01

    The Cygnus OB2 Association is one of the nearest and largest collections of massive stars in the Galaxy. Situated at the heart of the "Cygnus X" complex of star-forming regions and molecular clouds, its distance has proven elusive owing to the ambiguous nature of kinematic distances along this $\\ell\\simeq80$ degree sightline and the heavy, patchy extinction. In an effort to refine the three-dimensional geometry of key Cygnus~X constituents, we have measured distances to four eclipsing double-lined OB-type spectroscopic binaries that are probable members of Cyg~OB2. We find distances of $1.33\\pm0.17$, $1.32\\pm0.07$, $1.44\\pm0.18$, and $1.32\\pm0.13$ kpc toward MT91~372, MT91~696, CPR2002~A36, and Schulte~3 respectively. We adopt a weighted average distance of 1.33$\\pm$0.06~kpc. This agrees well with spectrophotometric estimates for the Association as a whole and with parallax measurements of protostellar masers in the surrounding interstellar clouds, thereby linking the ongoing star formation in these clouds wi...

  3. Cloud Structure of Galactic OB Cluster Forming Regions from Combining Ground and Space Based Bolometric Observations

    CERN Document Server

    Lin, Yuxin; Li, Di; Zhang, Zhiyu; Ginsburg, Adam; Pineda, Jaime E; Qian, Lei; Galván-Madrid, Roberto; McLeod, Anna Faye; Rosolowsky, Erik; Dale, James E; Immer, Katharina; Koch, Eric; Longmore, Steve; Walker, Daniel; Testi, Leonardo

    2016-01-01

    We have developed an iterative procedure to systematically combine the millimeter and submillimeter images of OB cluster-forming molecular clouds, which were taken by ground based (CSO, JCMT, APEX, IRAM-30m) and space telescopes (Herschel, Planck). For the seven luminous ($L$$>$10$^{6}$ $L_{\\odot}$) Galactic OB cluster-forming molecular clouds selected for our analyses, namely W49A, W43-Main, W43-South, W33, G10.6-0.4, G10.2-0.3, G10.3-0.1, we have performed single-component, modified black-body fits to each pixel of the combined (sub)millimeter images, and the Herschel PACS and SPIRE images at shorter wavelengths. The $\\sim$10$"$ resolution dust column density and temperature maps of these sources revealed dramatically different morphologies, indicating very different modes of OB cluster-formation, or parent molecular cloud structures in different evolutionary stages. The molecular clouds W49A, W33, and G10.6-0.4 show centrally concentrated massive molecular clumps that are connected with approximately radia...

  4. New VI photometry of the sdOB binary AA Dor and an improved photometric model

    CERN Document Server

    Hilditch, R W; Lynas-Gray, A E; Hill, G

    2003-01-01

    New VI CCD photometry, obtained with integration times of 20s, of the sdOB+degenerate-dwarf eclipsing binary system AA Dor has provided new complete light curves with an rms scatter about a mean curve of +/-0.004 mag. These data are analysed with an improved Light2 light curve synthesis code to yield more accurate determinations of the radii of both stars, the orbital inclination, and the flux ratio between the two components. These radii are only a little different from the values derived 25 years ago from less complete data, but the uncertainties on these values are improved by a factor of two. The apparent discrepancy remains between the surface gravity of the sdOB primary star obtained from the light-curve solution with the published spectroscopic orbit and that obtained from NLTE analysis of high-resolution spectra of the sdOB star. The substantial reflection effect in the system is adequately represented by the Light2 code with a bolometric albedo of unity in light curves extending from 0.35 microns to ...

  5. RGB-D Hand-Held Ob ject Recognition Based on Heterogeneous Feature Fusion

    Institute of Scientific and Technical Information of China (English)

    吕雄; 蒋树强; 王双

    2015-01-01

    Ob ject recognition has many applications in human-machine interaction and multimedia retrieval. However, due to large intra-class variability and inter-class similarity, accurate recognition relying only on RGB data is still a big challenge. Recently, with the emergence of inexpensive RGB-D devices, this challenge can be better addressed by leveraging additional depth information. A very special yet important case of object recognition is hand-held object recognition, as manipulating objects with hands is common and intuitive in human-human and human-machine interactions. In this paper, we study this problem and introduce an effective framework to address it. This framework first detects and segments the hand-held ob ject by exploiting skeleton information combined with depth information. In the ob ject recognition stage, this work exploits heterogeneous features extracted from different modalities and fuses them to improve the recognition accuracy. In particular, we incorporate handcrafted and deep learned features and study several multi-step fusion variants. Experimental evaluations validate the effectiveness of the proposed method.

  6. Galactic OB associations in the northern Milky Way Galaxy. I - Longitudes 55 deg to 150 deg

    Science.gov (United States)

    Garmany, C. D.; Stencel, R. E.

    1992-01-01

    The literature on all OB associations was reviewed, and their IRAS point source content was studied, between galactic longitude 55 and 150 deg. Only one third of the 24 associations listed by Ruprecht et al. (1981) have been the subject of individual studies designed to identify the brightest stars. Distances to all of these were recomputed using the method of cluster fitting of the B main sequence stars, which makes it poossible to reexamine the absolute magnitude calibration of the O stars, as well as for the red supergiant candidate stars. Also examined was the composite HR diagram for these associations. Associations with the best defined main sequences, which also tend to contain very young clusters, referred to here as OB clusters, have extremely few evolved B and A or red supergiants. Associations with poorly defined main sequences and few OB clusters have many more evolved stars. They also show an effect in the upper HR diagram referred to as a ledge by Fitzpatrick and Garmany (1990) in similar data for the Large Magellanic Cloud. It is suggested that the differences in the associations are not just observational selection effects but represent real differences in age and formation history.

  7. Relative Stabilities of Conserved and Non-Conserved Structures in the OB-Fold Superfamily

    Directory of Open Access Journals (Sweden)

    Andrei T. Alexandrescu

    2009-05-01

    Full Text Available The OB-fold is a diverse structure superfamily based on a β-barrel motif that is often supplemented with additional non-conserved secondary structures. Previous deletion mutagenesis and NMR hydrogen exchange studies of three OB-fold proteins showed that the structural stabilities of sites within the conserved β-barrels were larger than sites in non-conserved segments. In this work we examined a database of 80 representative domain structures currently classified as OB-folds, to establish the basis of this effect. Residue-specific values were obtained for the number of Cα-Cα distance contacts, sequence hydrophobicities, crystallographic B-factors, and theoretical B-factors calculated from a Gaussian Network Model. All four parameters point to a larger average flexibility for the non-conserved structures compared to the conserved β-barrels. The theoretical B-factors and contact densities show the highest sensitivity.Our results suggest a model of protein structure evolution in which novel structural features develop at the periphery of conserved motifs. Core residues are more resistant to structural changes during evolution since their substitution would disrupt a larger number of interactions. Similar factors are likely to account for the differences in stability to unfolding between conserved and non-conserved structures.

  8. Clustering between high-mass X-ray binaries and OB associations in the Milky Way

    CERN Document Server

    Bodaghee, Arash; Rodriguez, Jerome; James, J Berian

    2011-01-01

    We present the first direct measurement of the spatial cross-correlation function of high-mass X-ray binaries (HMXBs) and active OB star-forming complexes in the Milky Way. This result relied on a sample containing 79 hard X-ray selected HMXBs and 458 OB associations. Clustering between the two populations is detected with a significance above 7-sigmas for distances < 1 kpc. Thus, HMXBs closely trace the underlying distribution of the massive star-forming regions that are expected to produce the progenitor stars of HMXBs. The average offset of 0.4+-0.2 kpc between HMXBs and OB associations is consistent with being due to natal kicks at velocities of the order of 100+-50 km/s. The characteristic scale of the correlation function suggests an average kinematical age (since the supernova phase) of ~4 Myr for the HMXB population. Despite being derived from a global view of our Galaxy, these signatures of HMXB evolution are consistent with theoretical expectations as well as observations of individual objects.

  9. OB stars at the lowest Local Group metallicity: GTC-OSIRIS observations of Sextans A

    CERN Document Server

    Camacho, I; Herrero, A; Simón-Díaz, S

    2016-01-01

    Our aim is to find and classify OB stars in Sextans A, to later determine accurate stellar parameters of these blue massive stars in this low metallicity region $(Z \\sim 0.1 \\rm Z_{\\odot})$. Using UBV photometry, the reddening-free index Q and GALEX imaging, we built a list of blue massive star candidates in Sextans A. We obtained low resolution (R $\\sim$ 1000) GTC-OSIRIS spectra for a fraction of them and carried out spectral classification. For the confirmed O-stars we derive preliminary stellar parameters. The target selection criteria and observations were successful and have produced the first spectroscopic atlas of OB-type stars in Sextans A. From the whole sample of 18 observed stars, 12 were classified as early OB-types, including 5 O-stars. The radial velocities of all target stars are in agreement with their Sextans A membership, although three of them show significant deviations. We determined the stellar parameters of the O-type stars using the stellar atmosphere code FASTWIND, and revisited the s...

  10. Cosmic Ray Acceleration by Stellar Associations? The Case of Cygnus OB2

    CERN Document Server

    Butt, Y; Combi, J; Corcoran, M; Dame, T M; Drake, J; Bernado, M M K; Milne, P; Miniati, F; Pohl, M; Reimer, O; Romero, G; Rupen, M P; Butt, Yousaf; Benaglia, Paula; Combi, Jorge; Corcoran, Michael; Dame, Thomas; Drake, Jeremy; Bernado, Marina Kaufman; Milne, Peter; Miniati, Francesco; Pohl, Martin; Reimer, Olaf; Romero, Gustavo; Rupen, Michael

    2003-01-01

    The origins of all extra-solar cosmic rays -- both the ultra high-energy and lower energy Galactic variety -- remain unclear. It has been argued that the large scale shocks and turbulence induced by the multiple interacting supersonic winds from the many hot stars in young stellar associations may play a role in accelerating Galactic cosmic rays -- with or without the associated multiple supernova remnants (eg. Cesarsky & Montmerle, 1983; Bykov 2001). In this context, the report by the HEGRA Cherenkov telescope group of a steady and extended unidentified TeV gamma-ray source lying at the outskirts of Cygnus OB2 is particularly significant. This is the most massive stellar association known in the Galaxy, estimated to contain ~2600 OB type members alone indeed, Cyg OB2 also coincides with the non-variable MeV-GeV range unidentified EGRET source, 3EG 2033+4118. We summarise here the near-simultaneous follow-up observations of the extended TeV source region with the CHANDRA X-ray Observatory and the Very Lar...

  11. New OB star candidates in the Carina Arm around Westerlund 2 from VPHAS+

    CERN Document Server

    Mohr-Smith, M; Barentsen, G; Wright, N J; Napiwotzki, R; Corradi, R L M; Eislöffel, J; Groot, P; Kalari, V; Parker, Q A; Raddi, R; Sale, S E; Unruh, Y C; Vink, J S; Wesson, R

    2015-01-01

    O and early B stars are at the apex of galactic ecology, but in the Milky Way, only a minority of them may yet have been identified. We present the results of a pilot study to select and parametrise OB star candidates in the Southern Galactic plane, down to a limiting magnitude of $g=20$. A 2 square-degree field capturing the Carina Arm around the young massive star cluster, Westerlund 2, is examined. The confirmed OB stars in this cluster are used to validate our identification method, based on selection from the $(u-g, g-r)$ diagram for the region. Our Markov Chain Monte Carlo fitting method combines VPHAS+ $u, g, r, i$ with published $J, H, K$ photometry in order to derive posterior probability distributions of the stellar parameters $\\log(\\rm T_{\\rm eff})$ and distance modulus, together with the reddening parameters $A_0$ and $R_V$. The stellar parameters are sufficient to confirm OB status while the reddening parameters are determined to a precision of $\\sigma(A_0)\\sim0.09$ and $\\sigma(R_V)\\sim0.08$. The...

  12. OB glue paste technique for establishing nude mouse human gastric cancer orthotopic transplantation models

    Institute of Scientific and Technical Information of China (English)

    Jun Shi; Guo-Jing Zheng; Xiao-Mei Su; Ya-Lin Chen; Yan-Fang Liu; Ling Xu; Pin-Kang Wei; Shen Zhang; Zhi-Feng Qin; Jun Li; Da-Zhi Sun; Yan Xiao; Zhi-Hong Yu; Hui-Ming Lin

    2008-01-01

    AIM: To establish nude mouse human gastric cancer orthotopic transplantation models using OB glue paste technique.METHODS: Using OB glue paste technique,orthtopic transplantation models were established by implanting SGC-7901 and MKN-45 human gastric cancer cell strains into the gastric wall of nude mice.Biological features,growth of the implanted tumors,the success rate of transplantation and the rate of auto-metastasis of the two models were observed.RESULTS: The success rates of orthotopic transplantation of the two models were 94.20% and 96%.The rates of hepatic metastasis,pulmonary metastasis,peritoneal metastasis,lymphocytic metastasis and splenic metastasis were 42.13% and 94.20%,48.43% and 57.97%,30.83% and 36.96%,67.30% and 84.06%,and 59.75% and 10.53%,respectively.The occurrence of ascites was 47.80% and 36.96%.CONCLUSION: OB glue paste technique is easy to follow.The biological behaviors of the nude mouse human gastric cancer orthotopic transplantation models established with this technique are similar to the natural processes of growth and metastasis of human gastric cancer,and,therefore,can be used as an ideal model for experimental research of proliferative metastasis of tumors.

  13. The large scale view of the young stellar populations in the Orion OB1 Association

    Science.gov (United States)

    Briceno, Cesar; Calvet, Nuria

    2016-06-01

    The Orion OB1 association, at ~400 pc and with a wide range of ages (~1-10 Myr) and environmental conditions, is an ideal place to look at how stars form, first evolve and disperse among the general population of field stars. Also to study disk dispersal and the duration of the planet formation phase.However, despite spanning nearly 200 deg2 on the sky, almost all we know about Orion comes from studies of a limited fraction of the entire region, mostly of the youngest objects (~population, and following with spectroscopy to confirm members and characterize them.The ~2000 newly identified young low-mass stars are mostly located away from the molecular clouds, across tens of sq. deg. in the Orion OB1a and OB1b sub-associations, with ages in the range ~4-10 Myr. But within this general population we identify a significant fraction concentrated in distinct overdensities, most notably the ~7 Myr old 25 Orionis cluster. These stellar aggregates point to a previously unknown degree of substructure that has survived the dissipation of the parent molecular clouds. We also find that the Orion Nebula Cluster is surrounded by a few sq.deg. halo of young stars, as has been suggested by recent sudies.

  14. Pharmacological Effects of the Water Fraction of Key Components in the Traditional Chinese Prescription Mai Tong Fang on 3T3-L1 Adipocytes and ob/ob Diabetic Mice

    OpenAIRE

    Liang Ma; Li Huang; Heying Pei; Zhuowei Liu; Caifeng Xie; Lei Lei; Xiaoxin Chen; Haoyu Ye; Aihua Peng; Lijuan Chen

    2014-01-01

    Mai Tong Fang (MTF), a Chinese herbal combination, has been used for the treatment of diabetic nephropathy in traditional medical clinics in China. However, the anti-adipogenic and anti-hyperglycemic effects of MTF have not been fully elucidated, so this study explored these pharmacological activities in 3T3-L1 adipocytes and ob/ob mice, respectively, of the water fraction of milkvetch root, salviae miltiorrhizae and mulberry as key components of MTF. MTF was found to inhibit adipogenesis and...

  15. The asymmetric radio structure and record jet of giant quasar 4C 34.47

    Science.gov (United States)

    Hocuk, S.; Barthel, P. D.

    2010-11-01

    Context. Unification models for active galactic nuclei, AGN, predict that all quasars (radio sources associated with quasi-stellar objects) should be at a substantial angle with the sky plane. Aims: We test the predictions of the orientation unification model with the morphological and polarization properties of a giant quasar. Methods: The giant double-lobed radio source 4C 34.47, which is associated with quasi-stellar object B1721+343, is mapped at arcsecond scale resolution, and the data are subsequently analyzed within the context of current models for extragalactic radio sources. Results: Quasar 4C 34.47 displays a straight one-sided jet, measuring a record length of 380 kpc in its double-lobed radio structure. Assuming an intrinsically symmetric two-sided jet structure the radio source jet axis must be at least 33° away from the sky plane, that is within 57° from the line of sight. The radio polarization properties indicate that this giant source has largely outgrown the depolarizing halo that is generally associated with the host galaxies of powerful radio sources. The measured small depolarization asymmetry nevertheless agrees with its inferred orientation. Conclusions: All data for this giant radio source agree with its preferred orientation as predicted within the unification scheme for powerful radio sources. Seen under a small aspect angle the radio source is large, but not excessively large. The global properties of 4C 34.47 do not differ from other giant (old) FR2 radio sources: it is a slowly expanding low-luminosity radio source.

  16. Preparation of AlB sub 4 C composites for image analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, A.M.; Reiswig, R.D.; Hill, M.A.; Blumenthal, W.R.

    1990-01-01

    Composites made by infiltrating B{sub 4}C networks with aluminium, or its alloys are of interest for lightweight armor applications. Image analysis plays an important part in correlating the microstructures of such composites with their mechanical properties. Accurate image analysis requires a high degree of perfection in the metallographic preparation, which is particularly difficult where the phases present have such disparate hardness and reactivities. Two preparation procedures have been developed that produce adequate contrast and definition for analysis of key microstructural features. 8 refs., 5 figs., 1 tab.

  17. Core and halo structure of the quasar 4C 18. 68

    Energy Technology Data Exchange (ETDEWEB)

    Gower, A.C.; Hutchings, J.B.

    1986-08-01

    New VLA observations of the complex low-redshift quasar 4C 18.68, which was previously modeled as a precessing twin-jet source are presented. A 2-cm A configuration map fails to reveal the curvature of the jet near the nucleus predicted by this model. B and C configuration maps have been obtained to study the halo of the source, which is compact and shows no edge-brightened outer lobes. These results suggest that the radio source is not very old, and that it appears to have undergone two major changes of orientation in its less than 10 to the 7th yr history. 8 references.

  18. Core and halo structure of the quasar 4C 18.68

    International Nuclear Information System (INIS)

    New VLA observations of the complex low-redshift quasar 4C 18.68, which was previously modeled as a precessing twin-jet source are presented. A 2-cm A configuration map fails to reveal the curvature of the jet near the nucleus predicted by this model. B and C configuration maps have been obtained to study the halo of the source, which is compact and shows no edge-brightened outer lobes. These results suggest that the radio source is not very old, and that it appears to have undergone two major changes of orientation in its less than 10 to the 7th yr history. 8 references

  19. CT image digital measurement and clinical significance of C4 -C6 anterior fixed parameter

    Institute of Scientific and Technical Information of China (English)

    LI Xiaohe; LI Zhijun; GAO Shang

    2015-01-01

    Objective:To measure C3-C5 anterior fixed parametersment for the segmental anterior fixation surgery. Methods:The examination of the cervical spine in patients with CT imaging data were randomly selected from January 2009 - December 2012 , C4 - C6 cervical no lesions in 35 cases of imaging data were selected (20 males and 5 females , 25 to 50 years old, average 41. 2 years) ,The image data were rebuilded and measured di-ameter by Mimics 16. 01 software, vertebral body height, vertebrae transverse process hole diameter and diameter around, the left and right sides of the horizontal distance between the flange hole inside, left and right sides of the axis of the pedicle and sagittal axis and the horizontal axis angle and length were measured. Results and conclu-sion:the vertebral body diameter of C4-C6, (26. 67±0. 25) mm gradually increased to (32. 89±0. 12) mm, an-terior and posterior diameter of C4 -C6 ,(6. 89±0. 12) mm gradually increased to (8. 85±0. 44) mm, comparing differences between different segments were statistical significance;Vertebral body midline sagittal anterior, middle and posterior height from C4 [anterior was (7. 99 ±0. 51) mm, middle was(7. 09±0. 42) mm, posterior was (7. 76±0. 49) mm]. To C6 [anterior was (9. 89±0. 45 mm, middle was (8. 42±0. 75) mm, posterior was (8. 84±0. 26) mm], vertebral bodies were significant difference (P<0. 05); the vertebrae transverse process hole diameter and diameter around anterior and posterior were gradually increased with the increase of the sequence; on both sides of C4~C6 were by transverse process hole inside edge distance ( 25 . 10 ± 0 . 45 ) mm gradually increased to (28. 89±0. 56) mm, comparing differences between different segments were statistical significance;Pedicle axis , the sagittal axis and horizontal axis angle and length were gradually increasing with the increase of the cervical spine ordinal, difference is statistically significant.

  20. Synthetic LiFePO4/C without using inert gas

    Institute of Scientific and Technical Information of China (English)

    Guo Rong Hu; Xu Guang Gao; Zhong Dong Peng; Ke Du; Yan Jun Liu

    2007-01-01

    LiFePO4/C was synthesized by high temperature solid-state method with cheap Fe2O3, LiH2PO4 and glucose as raw materials in absence of inert gas. The sample had ordered olivine-type structure other impurities characterized by the test of X-ray diffraction(XRD). The charge-discharge test showed the sample could demonstrate 120.5 mAh/g at 0.2C rate with good cyclic capability. The powder microelectrode cyclic voltammetry test indicated that the redox process of the sample had good reversibility.

  1. The warm absorber in the radio-loud quasar 4C +74.26

    OpenAIRE

    Di Gesu, L.; Costantini, E.

    2016-01-01

    Outflows of photoionized gas are commonly detected in the X-ray spectra of Seyfert 1 galaxies. However, the evidence for this phenomenon in broad line radio galaxies, which are analogous to Seyfert 1 galaxies in the radio-loud regime, has so far been scarce. Here, we present the analysis of the X-ray absorption in the radio-loud quasar 4C +74.26. With the aim of characterizing the kinetic and the ionization conditions of the absorbing material, we fitted jointly the XMM-Newton Reflection Grat...

  2. Fermi LAT and Swift flare of the FSRQ 4C +40.25

    Science.gov (United States)

    Carpenter, Bryce; Ojha, Roopesh; Pivato, Giovanna; Fermi Large Area Telescope Collaboration

    2015-11-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed a gamma-ray flare from a source positionally consistent with the flat spectrum radio quasar (FSRQ) 4C +40.25 (also known as B2 1020+40 and 3FGL J1023.1+3952, Acero et al. 2015, ApJS 218, 23) with coordinates RA: 10h 23m 11.5661s, Dec: 39d 48m 15.378s, J2000, (Helmboldt et al. 2007, ApJ, 658, 203) and a redshift of 1.254 (Xu et al. 1994, AJ, 108, 395).

  3. Morphological research on radio loud AGN 4C39.25 using KaVA observations

    Science.gov (United States)

    Yoo, Hyemin; Sohn, Bong Won; Yi, Sukyoung; KaVA AGN WG members

    2016-01-01

    4C39.25 (0923+392) is a distant radio loud AGN placed at redshift 0.695. Its kilo-parsec scale jet observed by VLBA(Kollgaard et al. 1990) and parsec scale jet observed by VLBA(Kellermann et al. 1998) are misaligned. This might indicate episodic-jet activity which recently turned on. This object currently shows two stationary compact parsec-scale components:a bright jet component on the east and less luminous core on the west. Also, it is known that there have been superluminal jet components which are flowing from the core toward east, and then merging with the bright jet component (Marscher et al. 1991, Alberdi et al. 2000, Lister et al. 2013). Including the detection of broad emission lines(SDSS), its viewing angle was concluded to be small. However, the jet component being more luminous than the core is abnormal for a source with a small viewing angle. Furthermore, it has young radio galaxy-like properties such as non-variation in total flux(Alberdi et al. 1997, 2000, MOJAVE database) and a high frequency peak in the spectral energy distribution(Orienti et al 2007). In this case, it is more reliable to think that viewing angle of 4C39.25 is large. Korean VLBI Network (KVN) and VLBI Exploration of Radio Astronomy (VERA) Array (KaVA) is a cooperated VLBI system of Korea and Japan which provides high-frequency (23GHz and 43GHz) and high spatial resolution(1.2mas and 0.6mas). Their advantages of multi-wavelength and relatively high S/N ratio relative to its number of baseline allow us to discover the central region and dim structures of 4C39.25. We present results of several epochs observed during 2013 to 2014, focusing on morphological changes of 4C39.25 using KaVA images. According to these results, we were able to find a recently emitted counter-jet component for images of first 6 epochs. Also the counter-jet component propagates along a curved trajectory, and it shows an extreme superluminal motion. This might indicate a necessity of relatively large viewing

  4. Detection of a Large Arc of Ionized Hydrogen Far Above the Cas OB6 Association A Superbubble Blowout into the Galactic Halo?

    CERN Document Server

    Reynolds, R J; Haffner, L M

    2001-01-01

    The Wisconsin H-Alpha Mapper (WHAM) Northern Sky Survey has revealed a loop of H II reaching 1300 pc from the Galactic midplane above the Cas OB6 association in the Perseus sprial arm. This enormous feature surrounds and extends far above the "W4 Chimney" identified by Normandeau et al. and appears to be associated with the star formation activity near the W3/W4/W5 H II region complex. The existence of this ionized structure suggests that past episodes of massive star formation have cleared the H I from an enormous volume above the Perseus arm, allowing Lyman continuum photons from O stars near the Galactic midplane to reach into the halo.

  5. Characterization of the Young Open Cluster G144.9+0.4 in the Camelopardalis OB1 Association

    CERN Document Server

    Lin, Chien-Cheng; Panwar, Neelam

    2013-01-01

    Our star-count analysis of the 2MASS point sources resulted in an identification of the star cluster G144.9+0.4. The cluster was found, but not characterized, by \\citet{glu10}. We show that the cluster is physically associated with the Cam\\,OB1 association at a distance of about 1 kpc and with an age of 1--2 Myr. Pre-main sequence stars are identified, on the basis of photometric and proper motion data. A total of 91 additional OB star candidates were found in the subgroup 1A and 1B, a significant increase from the currently known 43 OB stars. The OB members show an age spread that indicates a sustained star formation for at least the last 10--15 years. The young cluster G144.9+0.4 represents the latest episode of sequence star formation in this cloud complex.

  6. A multi-epoch XMM-Newton campaign on the core of the massive Cygnus OB2 association

    Science.gov (United States)

    Rauw, G.

    2011-12-01

    Context. Cyg OB2 is one of the most massive associations of O-type stars in our Galaxy. Despite the large interstellar reddening towards Cyg OB2, many studies, spanning a wide range of wavelengths, have been conducted to more clearly understand this association. X-ray observations provide a powerful tool to overcome the effect of interstellar absorption and study the most energetic processes associated with the stars in Cyg OB2. Aims: We analyse XMM-Newton data to investigate the X-ray and UV properties of massive O-type stars as well as low-mass pre-main sequence stars in Cyg OB2. Methods: We obtained six XMM-Newton observations of the core of Cyg OB2. In our analysis, we pay particular attention to the variability of the X-ray bright OB stars, especially the luminous blue variable candidate Cyg OB2 #12. Results: We find that X-ray variability is quite common among the stars in Cyg OB2. Whilst short-term variations are restricted mostly to low-mass pre-main sequence stars, one third of the OB stars display long-term variations. The X-ray flux of Cyg OB2 #12 varies by 37%, over timescales from days to years, whilst its mean log LX/Lbol amounts to - 6.10. Conclusions: These properties suggest that Cyg OB2 #12 is either an interacting-wind system or displays a magnetically confined wind. Two other X-ray bright O-type stars (MT91 516 and CPR2002 A11) display variations that suggest they are interacting wind binary systems. Based on observations collected with XMM-Newton, an ESA Science Mission with instruments and contributions directly funded by ESA Member States and the USA (NASA).Full Table 2 and Table 4 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/536/A31

  7. 4C 的(r1,r2,r3,r4)−冠的优美性%The gracefulness of the (r1, r2, r3, r4)−corona of the cycle 4C

    Institute of Scientific and Technical Information of China (English)

    吴跃生

    2012-01-01

      讨论了圈4C 的( r r 21,,, r r 43)−冠的优美性,用构造性的方法给出了圈4C 的( r r 21,,, r r 43)−冠的优美标号。证明了圈4C 的( r r 21,,, r r 43)−冠都是交错图。%  Discussed the gracefulness of the( r r 2 1 , , , r r 4 3 )−corona of the cycle 4C .The graceful labeling was given.Proved that the( r r 2 1 , , , r r 4 3 )−corona of the cycle 4C are graceful graph.

  8. ObsPy: A Python Toolbox for Seismology/Seismological Observatories

    Science.gov (United States)

    Megies, T.; Barsch, R.; Beyreuther, M.; Krischer, L.; Wassermann, J. M.; ObsPy Development Team

    2011-12-01

    Python enables the user to combine the possibilities of a full-blown programming language with the flexibility of an interactive scripting language. Its extensive standard library and many freely available high quality scientific modules cover most needs in developing scientific processing workflows. The goal of the ObsPy project (http://www.obspy.org) is to facilitate rapid application development for seismology by extending Python's capabilities to fit the specific needs that arise when working with seismological data. It provides read and write support for many common waveform file formats (e.g. MiniSEED, SAC, GSE2, SEISAN, ...) and metadata formats (e.g. SEED, Dataless SEED, XML-SEED, RESP, ...). Several available client modules make it possible to directly acquire waveform data and metadata as well as earthquake event data from data centers communicating with ArcLink (http://www.webdc.eu), Fissures (http://www.iris.edu/dhi) and SeisHub servers (http://www.seishub.org) and by connecting to webservices provided by IRIS (http://www.iris.edu/ws/) and NERIES (http://www.seismicportal.eu/). Finally there is a growing signal processing toolbox that covers many often needed routines for filtering, triggering, instrument correction/simulation, complex trace analysis, array analysis and many more. Recent additions to ObsPy include calculation of probabilistic power spectral densities, relative instrument calibration and wrappers for the IASPEI-tau traveltime package and IRIS's evalresp. In combination with well developed, free Python packages like NumPy (http://numpy.scipy.org), SciPy (http://scipy.org), IPython (http://ipython.scipy.org), Matplotlib (http://matplotlib.sourceforge.net) and PyQt (http://www.riverbankcomputing.co.uk/software/pyqt), ObsPy makes it possible to develop complete workflows in Python, ranging from reading/requesting data via signal analysis and data processing to visualization in GUI applications and output of modified or derived data. ObsPy is

  9. Consolidation of B4C-TaB2 eutectic composites by spark plasma sintering

    Directory of Open Access Journals (Sweden)

    Dmytro Demirskyi

    2015-12-01

    Full Text Available The in situ synthesis/consolidation of B4C-TaB2 eutectic composites by spark plasma sintering (SPS is reported. The microstructure–property relations were determined for composites with the B4C-TaB2 eutectic composition as functions of TaB2 content, and TaB2-TaB2 interlamellar spacing. A clear maximum in fracture toughness was identified (∼4.5 MPa m1/2 for eutectic composites with interlamellar spacing between 0.9 and 1.1 μm. The composites with the hypereutectic composition of 40 mol.% TaB2 obtained by SPS exhibited lower Vickers hardness (25–26 GPa but higher indentation fracture toughness (up to 4.9 MPa m1/2 than eutectic composites with 30–35 mol.% of TaB2.

  10. The asymmetric radio structure and record jet of giant quasar 4C34.47

    CERN Document Server

    Hocuk, S

    2010-01-01

    Giant double-lobed radio source 4C34.47 displays a straight one-sided jet, measuring a record length of 380kpc, in its double-lobed radio structure. Assuming an intrinsically symmetric two-sided jet structure the radio source jet axis must be at least 33 degrees away from the sky plane, that is within 57 degrees from the line of sight. The radio polarization properties indicate that this giant source has largely outgrown the depolarizing halo generally associated with the host galaxies of powerful radio sources. The measured small depolarization asymmetry is nevertheless in accordance with its inferred orientation. All data for this giant radio source are in agreement with its preferred orientation as predicted within the unification scheme for powerful radio sources. Seen under a small aspect angle the radio source is large but not excessively large. The global properties of 4C34.47 do not differ from other giant (old) FR2 radio sources: it is a slowly expanding low-luminosity radio source.

  11. On the Merging Cluster Abell 578 and Its Central Radio Galaxy 4C +67.13

    CERN Document Server

    Hagino, K; Siemiginowska, A; Cheung, C C; Koziel-Wierzbowska, D; Szostek, A; Madejski, G; Harris, D E; Simionescu, A; Takahashi, T

    2015-01-01

    Here we analyze radio, optical, and X-ray data for a peculiar cluster Abell 578. This cluster is not fully relaxed and consists of two merging sub-systems. The brightest cluster galaxy, CGPG 0719.8+6704, is a pair of interacting ellipticals with projected separation $\\sim$10 kpc, the brighter of which hosts the radio source 4C +67.13. The Fanaroff-Riley type-II radio morphology of 4C +67.13 is unusual for central radio galaxies in local Abell clusters. Our new optical spectroscopy revealed that both nuclei of the CGPG 0719.8+6704 pair are active, albeit at low accretion rates corresponding to the Eddington ratio $\\sim10^{-4}$ (for the estimated black hole masses of $\\sim 3 \\times 10^8\\,M_\\odot$ and $\\sim 10^9 \\, M_\\odot$). The gathered X-ray ({\\it Chandra}) data allowed us to confirm and to quantify robustly the previously noted elongation of the gaseous atmosphere in the dominant sub-cluster, as well as a large spatial offset ($\\sim 60$\\,kpc projected) between the position of the brightest cluster galaxy and...

  12. Helium bubble evolution in ion irradiated Al/B4C metal matrix composite

    International Nuclear Information System (INIS)

    Graphical abstract: Scheme of combined irradiation includes a pre-implantation of 400 keV He+ to 1.0 × 1016 ions/cm2 followed by a 1.5 MeV proton irradiation to 2.2 × 1019 ions/cm2 on the perpendicular surface. TEM samples were prepared by FIB. The area suffered with both He+ pre-implantation and proton irradiation was marked as light blue. - Abstract: Helium behavior in Al/B4C metal matrix composite with two different sets of ion irradiation conditions has been investigated by transmission electron microscopy. Helium bubbles in Al were found to be much larger than those in B4C after a helium fluence of 1.5 × 1017 ions/cm2 at the room temperature. Also, bubbles at grain boundaries and their vicinity in aluminum are faceted. With additional proton irradiation, a bubble denuded zone along the aluminum grain boundary appears. The results are discussed in terms of the energetics of the material system

  13. AGN Spectral Energy Distribution of GLAST Telescope Network Program Object 4C 29.45

    Science.gov (United States)

    Adkins, J.; Stefaniak, L.; Rapp, S.; Hinckley, B.; Lacy, M.

    2006-06-01

    The Gamma-Ray Large Area Space Telescope (GLAST) to be launched in 2006 has a proposed observing list that includes AGNs and Polars bright enough to be observed optically by amateurs and students. This observing list is maintained by the GLAST Telescope Network (GTN) and includes a number of objects that have yet to be observed by the Spitzer Space Telescope. Our project observed one of these objects, 4C 29.45, with the Spitzer MIPS and the IRAC instruments and also using ground based telescopes. Observations were made in seven infrared bands with Spitzer. Additional observations made from the ground by students, amateur astronomers, and small college observatories in R,V, and I were nearly simultaneous with the Spitzer observations. We have used this data to construct the Spectral Energy Distribution (SED) of 4C 29.45. We compare these data to models of the dust emission from the torus, sychrotron emission from the radio core, and thermal emission from the accretion disk to determine the relative importance of the different emission mechanisms in this object as a function of wavelength.

  14. Molecular dynamics simulation of nanoindentation of Fe3C and Fe4C

    International Nuclear Information System (INIS)

    Study of nanomechanical response of iron carbides is important because presence of iron carbides greatly influences the performance and longevity of steel components. This work contributes to the literature by exploring nanoindentation of Fe3C and tetrahedral-Fe4C using molecular dynamics simulation. The chemical interactions of iron and carbon were described through an analytical bond order inter-atomic potential (ABOP) energy function. The indentations were performed at an indentation speed of 50 m/s and a repeat trial was performed at 5 m/s. Load–displacement (P–h) curve for both these carbides showed residual indentation depth and maximum indentation depth (hf/hmax) ratio to be higher than 0.7 i.e. a circumstance where Oliver and Pharr method was not appropriate to be applied to evaluate the material properties. Alternate evaluation revealed Fe3C to be much harder than Fe4C. Gibbs free energy of formation and radial distribution function, coupled with state of the average local temperature and von Mises stresses indicate the formation of a new phase of iron-carbide. Formation of this newer phase was found to be due to deviatoric strain rather than the high temperature induced in the substrate during nanoindentation

  15. Multifrequency Studies of the Peculiar Quasar 4C +21.35 During the 2010 Flaring Activity

    CERN Document Server

    Ackermann, M; Allafort, A; Antolini, E; Barbiellini, G; Bastieri, D; Bellazzini, R; Bissaldi, E; Bonamente, E; Bregeon, J; Brigida, M; Bruel, P; Buehler, R; Buson, S; Caliandro, G A; Cameron, R A; Caraveo, P A; Cavazzuti, E; Cecchi, C; Chaves, R C G; Chekhtman, A; Chiang, J; Chiaro, G; Ciprini, S; Claus, R; Cohen-Tanugi, J; Conrad, J; Cutini, S; D'Ammando, F; de Palma, F; Dermer, C D; Silva, E do Couto e; Donato, D; Drell, P S; Favuzzi, C; Finke, J; Focke, W B; Franckowiak, A; Fukazawa, Y; Fusco, P; Gargano, F; Gasparrini, D; Gehrels, N; Giglietto, N; Giordano, F; Giroletti, M; Godfrey, G; Grenier, I A; Guiriec, S; Hayashida, M; Hewitt, J W; Horan, D; Hughes, R E; Iafrate, G; Johnson, A S; Knodlseder, J; Kuss, M; Lande, J; Larsson, S; Latronico, L; Longo, F; Loparco, F; Lovellette, M N; Lubrano, P; Mayer, M; Mazziotta, M N; McEnery, J E; Michelson, P F; Mizuno, T; Monzani, M E; Morselli, A; Moskalenko, I V; Murgia, S; Nemmen, R; Nuss, E; Ohsugi, T; Orienti, M; Orlando, E; Perkins, J S; Pesce-Rollins, M; Piron, F; Pivato, G; Porter, T A; Rainò, S; Razzano, M; Reimer, A; Reimer, O; Sanchez, D A; Schulz, A; Sgrò, C; Siskind, E J; Spandre, G; Spinelli, P; Stawarz, L; Takahashi, H; Takahashi, T; Thayer, J G; Thayer, J B; Thompson, D J; Tinivella, M; Torres, D F; Tosti, G; Troja, E; Usher, T L; Vandenbroucke, J; Vasileiou, V; Vianello, G; Vitale, V; Werner, M; Winer, B L; Wood, D L; Wood, K S; Aleksic, J; Ansoldi, S; Antonelli, L A; Antoranz, P; Babic, A; Bangale, P; de Almeida, U Barres; Barrio, J A; Gonzalez, J Becerra; Bednarek, W; Berger, K; Bernardini, E; Biland, A; Blanch, O; Bock, R K; Bonnefoy, S; Bonnoli, G; Borracci, F; Bretz, T; Carmona, E; Carosi, A; Fidalgo, D Carreto; Colin, P; Colombo, E; Contreras, J L; Cortina, J; Covino, S; Da Vela, P; Dazzi, F; De Angelis, A; De Caneva, G; De Lotto, B; Mendez, C Delgado; Doert, M; Dominguez, A; Prester, D Dominis; Dorner, D; Doro, M; Einecke, S; Eisenacher, D; Elsaesser, D; Farina, E; Ferenc, D; Fonseca, M V; Font, L; Frantzen, K; Fruck, C; Lopez, R J Garcia; Garczarczyk, M; Terrats, D Garrido; Gaug, M; Giavitto, G; Godinovic, N; Munoz, A Gonzalez; Gozzini, S R; Hadasch, D; Herrero, A; Hildebrand, D; Hose, J; Hrupec, D; Idec, W; Kadenius, V; Kellermann, H; Knoetig, M L; Kodani, K; Konno, Y; Krause, J; Kubo, H; Kushida, J; La Barbera, A; Lelas, D; Lewandowska, N; Lindfors, E; Lombardi, S; Lopez, M; Lopez-Coto, R; Lopez-Oramas, A; Lorenz, E; Lozano, I; Makariev, M; Mallot, K; Maneva, G; Mankuzhiyil, N; Mannheim, K; Maraschi, L; Marcote, B; Mariotti, M; Martinez, M; Mazin, D; Menzel, U; Meucci, M; Miranda, J M; Mirzoyan, R; Moralejo, A; Munar-Adrover, P; Nakajima, D; Niedzwiecki, A; Nishijima, K; Nilsson, K; Nowak, N; Orito, R; Overkemping, A; Paiano, S; Palatiello, M; Paneque, D; Paoletti, R; Paredes, J M; Paredes-Fortuny, X; Partini, S; Persic, M; Prada, F; Moroni, P G Prada; Prandini, E; Preziuso, S; Puljak, I; Reinthal, R; Rhode, W; Ribo, M; Rico, J; Garcia, J Rodriguez; Rugamer, S; Saggion, A; Saito, T; Saito, K; Salvati, M; Satalecka, K; Scalzotto, V; Scapin, V; Schultz, C; Schweizer, T; Shore, S N; Sillanpaa, A; Sitarek, J; Snidaric, I; Sobczynska, D; Spanier, F; Stamatescu, V; Stamerra, A; Steinbring, T; Storz, J; Sun, S; Suric, T; Takalo, L; Takami, H; Tavecchio, F; Temnikov, P; Terzic, T; Tescaro, D; Teshima, M; Thaele, J; Tibolla, O; Toyama, T; Treves, A; Vogler, P; Wagner, R M; Zandanel, F; Zanin, R; Aller, M F; Angelakis, E; Blinov, D A; Djorgovski, S G; Drake, A J; Efimova, N V; Gurwell, M A; Homan, D C; Jordan, B; Kopatskaya, E N; Kovalev, Y Y; Kurtanidze, O M; Lahteenmaki, A; Larionov, V M; Lister, M L; Nieppola, E; Nikolashvili, M G; Ros, E; Savolainen, T; Sigua, L A; Tornikoski, M; .,

    2014-01-01

    The discovery of rapidly variable Very High Energy (VHE; E > 100 GeV) gamma-ray emission from 4C +21.35 (PKS 1222+216) by MAGIC on 2010 June 17, triggered by the high activity detected by the Fermi Large Area Telescope (LAT) in high energy (HE; E > 100 MeV) gamma-rays, poses intriguing questions on the location of the gamma-ray emitting region in this flat spectrum radio quasar (FSRQ). We present multifrequency data of 4C +21.35 collected from centimeter to VHE during 2010 to investigate the properties of this source and discuss a possible emission model. The first hint of detection at VHE was observed by MAGIC on 2010 May 3, soon after a gamma-ray flare detected by Fermi-LAT that peaked on April 29. The same emission mechanism may therefore be responsible for both the HE and VHE emission during the 2010 flaring episodes. Two optical peaks were detected on 2010 April 20 and June 30, close in time but not simultaneous with the two gamma-ray peaks, while no clear connection was observed between the X-ray an gam...

  16. Synthesis of LiFePO4/C composite electrode with enhanced electrochemical performance

    Institute of Scientific and Technical Information of China (English)

    HU Guo-rong; GAO Xu-guang; PENG Zhong-dong; CHEN Zhao-yong; TAN Xian-yan; YU Xiao-yuan

    2005-01-01

    LiFePO4/C composite was synthesized by high temperature solid-state reaction using iron( Ⅱ ) oxalate,ammonium di-hydrogen phosphate and lithium carbonate with a kind of carbohydrate dissolved in the dispersant(ethanol) as carbon sources added to the synthetic precursor. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy observations(SEM), charge/discharge test, cyclic voltammetry(CV) and carbon analysis. The results show that the synthesis of LiFePO4/C has ordered olivine structure. The carbon has two advantages: optimizing particle size of LiFePO4 and increasing the electronic conductivity and high Li+ diffusivity.The cathode material can demonstrate a charge/discharge flat voltage of 3.4 V(vs Li+/Li). Especially the active material with 15 % and 20% carbohydrate added according to the final product of lithium iron phosphate shows very respectively at 0. 1 C rate and the carbon contents in the final production are only 5.17% and 5.29%, respectively.

  17. Preparation and characterization of B{sub 4}C coatings for advanced research light sources

    Energy Technology Data Exchange (ETDEWEB)

    Störmer, Michael, E-mail: michael.stoermer@hzg.de [Helmholtz-Zentrum Geesthacht, Max-Planck-Strasse 1, D-21502 Geesthacht (Germany); Siewert, Frank [Helmholtz-Zentrum Berlin, Albert-Einstein-Strasse 15, 12489 Berlin (Germany); Sinn, Harald [European XFEL GmbH, Albert-Einstein-Ring 19, 22761 Hamburg (Germany)

    2016-01-01

    The challenging specifications for long X-ray mirrors for upcoming free-electron lasers can be achieved, especially for maintaining below 2 nm peak-to-valley shape error along the optical aperture of approximately 1 m-long mirrors. X-ray optical elements are required for beam transport at the current and upcoming free-electron lasers and synchrotron sources. An X-ray mirror is a combination of a substrate and a coating. The demand for large mirrors with single layers consisting of light or heavy elements has increased during the last few decades; surface finishing technology is currently able to process mirror lengths up to 1 m with microroughness at the sub-nanometre level. Additionally, thin-film fabrication is able to deposit a suitable single-layer material, such as boron carbide (B{sub 4}C), some tens of nanometres thick. After deposition, the mirror should provide excellent X-ray optical properties with respect to coating thickness errors, microroughness values and slope errors; thereby enabling the mirror to transport the X-ray beam with high reflectivity, high beam flux and an undistorted wavefront to an experimental station. At the European XFEL, the technical specifications of the future mirrors are extraordinarily challenging. The acceptable shape error of the mirrors is below 2 nm along the whole length of 1 m. At the Helmholtz-Zentrum Geesthacht (HZG), amorphous layers of boron carbide with thicknesses in the range 30–60 nm were fabricated using the HZG sputtering facility, which is able to cover areas up to 1500 mm long by 120 mm wide in one step using rectangular B{sub 4}C sputtering targets. The available deposition area is suitable for the specified X-ray mirror dimensions of upcoming advanced research light sources such as the European XFEL. The coatings produced were investigated by means of X-ray reflectometry and interference microscopy. The experimental results for the B{sub 4}C layers are discussed according to thickness uniformity, density

  18. The design, microstructure and tensile properties of B{sub 4}C particulate reinforced 6061Al neutron absorber composites

    Energy Technology Data Exchange (ETDEWEB)

    Chen, H.S. [School of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024 (China); Wang, W.X., E-mail: Wangwenxian@tyut.edu.cn [School of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024 (China); Li, Y.L.; Zhang, P. [School of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024 (China); Nie, H.H. [Shanxi Coal-Mining Administrators College, Taiyuan 030024 (China); Wu, Q.C. [School of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024 (China)

    2015-05-25

    Highlights: • B{sub 4}C/Al composites for neutron shielding were designed by MCNP program. • B{sub 4}C/Al composite were fabricated by vacuum hot pressing followed by hot rolling. • The properties can be enhanced by vacuum hot pressing followed by hot rolling. - Abstract: Based on the Monte Carlo Particle transport program MCNP, a novel boron carbide particulate reinforced 6061Al composite for neutron shielding (B{sub 4}C/6061Al NACs) with high strength and low density was designed. The NACs with four volume fractions (10%, 20%, 30% and 40%) were successfully fabricated by vacuum hot pressing followed by hot rolling (VPHR) in atmospheric environments. The calculation results indicated that the neutron transmission ratio decreased with the increasing of B{sub 4}C content and the thickness of plates. B{sub 4}C particle is uniformly distributed in the matrix, exhibiting the good bonding in interface. The phases of neutron absorbers were mainly B{sub 4}C and Al, and a spot of AlB{sub 2} and Al{sub 3}BC. The grain of the matrix was refined and the dislocation was formed around the particles. With increasing the B{sub 4}C content, the particles gathered, breakage appeared, and the tensile strength of composite first increased and then decreased. The failure mode of B{sub 4}C/6061Al NACs included: the interfacial debonding and the cleavage fracture of particles.

  19. Interfacial properties and electron structure of Al/B4C interface: A first-principles study

    Science.gov (United States)

    Xian, Yajiang; Qiu, Ruizhi; Wang, Xin; Zhang, Pengcheng

    2016-09-01

    This research aims at investigating the structural, mechanical and electronic properties of the Al (111)/B4C (0001) interface by first-principles calculations. This model geometry Al (111)/B4C (0001) is chosen because the close-packed planes of Al and B4C have the (111) and (0001) orientation, respectively, and the lattice mismatch is only ∼2.1%. Among four B4C (0001) surfaces with different terminations, our calculation of surface free energies predicted that C-terminated B4C (0001) surface is the most stable one. Relaxed atomic geometries, the work of adhesion and interfacial free energies were calculated for three C-terminated B4C (0001)/Al (111) interfaces with different stacking sequences (top-site, hollow-site, and bridge-site). Results reveal that the relaxed top-site (hollow-site-like) Al/B4C interface has the best adhesion force and also be the most stable. The interfacial electron structure including charge density difference, Bader charge and density of states (DOS) is analyzed to determine the nature of metal/carbide bonding and we find the formation of Alsbnd C bond and possibly the formation of Al4C3 in the interface.

  20. C9orf72 G(4)C(2) repeat expansions in Alzheimer's disease and mild cognitive impairment

    NARCIS (Netherlands)

    Cacace, Rita; Van Cauwenberghe, Caroline; Bettens, Karolien; Gijselinck, Ilse; van der Zee, Julie; Engelborghs, Sebastiaan; Vandenbulcke, Mathieu; Van Dongen, Jasper; Baumer, Veerle; Dillen, Lubina; Mattheijssens, Maria; Peeters, Karin; Cruts, Marc; Vandenberghe, Rik; De Deyn, Peter P.; Van Broeckhoven, Christine; Sleegers, Kristel

    2013-01-01

    C9orf72 G(4)C(2) repeat expansion is a major cause of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Its role in Alzheimer's disease (AD) is less clear. We assessed the prevalence of G(4)C(2) pathogenic repeat expansions in Flanders-Belgian patients with clinical AD or mild cog

  1. Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes.

    Science.gov (United States)

    Chung, Min-Yu; Park, Hea Jin; Manautou, Jose E; Koo, Sung I; Bruno, Richard S

    2012-04-01

    Oxidative and nitrative stress responses resulting from inflammation exacerbate liver injury associated with nonalcoholic steatohepatitis (NASH) by inducing lipid peroxidation and protein nitration. The objective of this study was to investigate whether the anti-inflammatory properties of green tea extract (GTE) would protect against NASH by suppressing oxidative and nitrative damage mediated by proinflammatory enzymes. Obese mice (ob/ob) and their 5-week-old C57BL6 lean littermates were fed 0%, 0.5% or 1% GTE for 6 weeks (n=12-13 mice/group). In obese mice, hepatic lipid accumulation, inflammatory infiltrates and serum alanine aminotransferase activity were markedly increased, whereas these markers of hepatic steatosis, inflammation and injury were significantly reduced among obese mice fed GTE. GTE also normalized hepatic 4-hydroxynonenal and 3-nitro-tyrosine (N-Tyr) concentrations to those observed in lean controls. These oxidative and nitrative damage markers were correlated with alanine aminotransferase (P<.05; r=0.410-0.471). Improvements in oxidative and nitrative damage by GTE were also associated with lower hepatic nicotinamide adenine dinucleotide phosphate oxidase activity. Likewise, GTE reduced protein expression levels of hepatic myeloperoxidase and inducible nitric oxide synthase and decreased the concentrations of nitric oxide metabolites. Correlative relationships between nicotinamide adenine dinucleotide phosphate oxidase and hepatic 4-hydroxynonenal (r=0.364) as well as nitric oxide metabolites and N-Tyr (r=0.598) suggest that GTE mitigates lipid peroxidation and protein nitration by suppressing the generation of reactive oxygen and nitrogen species. Further study is warranted to determine whether GTE can be recommended as an effective dietary strategy to reduce the risk of obesity-triggered NASH. PMID:21543212

  2. Inhibition of Leptin-ObR Interaction Does not Prevent Leptin Translocation Across a Human Blood-Brain Barrier Model.

    Science.gov (United States)

    Gonzalez-Carter, D; Goode, A E; Fiammengo, R; Dunlop, I E; Dexter, D T; Porter, A E

    2016-06-01

    The adipocyte-derived hormone leptin regulates appetite and energy homeostasis through the activation of leptin receptors (ObR) on hypothalamic neurones; hence, leptin must be transported through the blood-brain barrier (BBB) to reach its target sites in the central nervous system. During obesity, however, leptin BBB transport is decreased, in part precluding leptin as a viable clinical therapy against obesity. Although the short isoform of the ObR (ObRa) has been implicated in the transport of leptin across the BBB as a result of its elevated expression in cerebral microvessels, accumulating evidence indicates that leptin BBB transport is independent of ObRa. In the present study, we employed an ObR-neutralising antibody (9F8) to directly examine the involvement of endothelial ObR in leptin transport across an in vitro human BBB model composed of the human endothelial cell line hCMEC/D3. Our results indicate that, although leptin transport across the endothelial monolayer was nonparacellular, and energy- and endocytosis-dependent, it was not inhibited by pre-treatment with 9F8, despite the ability of the latter to recognise hCMEC/D3-expressed ObR, prevent leptin-ObR binding and inhibit leptin-induced signal transducer and activator of transcription 3 (STAT-3) phosphorylation in hCMEC/D3 cells. Furthermore, hCMEC/D3 cells expressed the transporter protein low-density lipoprotein receptor-related protein-2 (LRP-2), which is capable of binding and endocytosing leptin. In conclusion, our results demonstrate that leptin binding to and signalling through ObR is not required for efficient transport across human endothelial monolayers, indicating that ObR is not the primary leptin transporter at the human BBB, a role which may fall upon LRP-2. A deeper understanding of leptin BBB transport will help clarify the exact causes for leptin resistance seen in obesity and aid in the development of more efficient BBB-penetrating leptin analogues. PMID:27037668

  3. Dry Sliding Tribological Studies of AA6061-B4C-Gr Hybrid Composites

    Science.gov (United States)

    Monikandan, V. V.; Joseph, M. A.; Rajendrakumar, P. K.

    2016-10-01

    The dry sliding behavior of stir-cast AA6061-10 wt.% B4C composites containing 2.5, 5 and 7.5 wt.% graphite particles was studied as a function of applied load, sliding speed and sliding distance on a pin-on-disk tribotester. The wear rate and friction coefficient increased with increase in applied load and sliding distance. The increase in graphite addition reduced the increase in wear rate and friction coefficient in the sliding speed range 2-2.5 m/s. Scanning electron microscopy of the worn pin revealed a graphite tribolayer, and transmission electron microscopy revealed overlapping deformation bands under 30 N applied load. Upon increasing the applied load to 40 N, welded region with fine crystalline structure was formed due to dynamic recrystallization of AA6061 alloy matrix.

  4. Distorted structure in the small high-redshift radio source 4C 29.50

    International Nuclear Information System (INIS)

    The powerful radio source 4C 29.50, which is identified with a quasar at redshift 1.927, has been mapped with a variety of instruments, frequencies, and resolutions. The highest resolution is 30 mas, corresponding to about 150 pc at this redshift. The projected overall dimensions of the radio source are subgalactic, and the structure is very distorted. There are apparent sudden deflections of a jet emerging from the quasar core, and it is proposed that these are due to interaction with a dense, clumpy interstellar eenvironment. The great power of the source and the small scales on which the deflections occur yield constraints on the properties of this environment. 31 references

  5. B4C solid target boronization of the MST reversed-field pinch

    International Nuclear Information System (INIS)

    A solid rod of hot-pressed boron carbide is being used as the source of boron during boronization of MST. The most striking result of this procedure is the reduction in oxygen contamination of the plasma (O III radiation, characteristic of oxygen at the edge, falls by about a factor of 3 after boronization.). The radiated power fraction drops to about half its initial value. Particle reflux from the wall is also lowered, making density control simpler. The rod (12.7 mm diameter) is inserted into the edge plasma of normal high-power RFP discharges. B4C is ablated from the surface of the rod and deposited in a thin film (a-B/C:H) on the walls and limiters. The energy flux carried by ''superthermal'' (not ''runaway'') electrons at the edge of MST appears to enhance the efficient, non-destructive ablation of the boron carbide rod

  6. Revisiting the electrochemical impedance behaviour of the LiFePO4/C cathode

    Indian Academy of Sciences (India)

    Hua Ju; Jun Wu; Yanhui Xu

    2013-05-01

    In the present work, the electrochemical behaviour of LiFePO4/C electrode has been reported. Specially, the electrochemical impedance spectroscopies (EIS) have been studied in detail. The discharge capacity is more than 120 mAh/g. There are two semicircles being found in the Nyquist plot for the cycled electrode and one semicircle for the as-prepared electrode. It is found that the interface capacitance is in an order of magnitude of 10 F/cm2 for the high-frequency semicircle, while for the second semicircle the interface capacitance is 5.3 ∼ 45.4 × 103 F/cm2. It could be concluded that the high-frequency semicircle is to correspond to the charge transfer process. The function of the carbon layer is also briefly discussed.

  7. Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    DEFF Research Database (Denmark)

    Leurs, Ulrike; Lohse, Brian; Rand, Kasper Dyrberg;

    2014-01-01

    Inhibition of histone demethylases has within recent years advanced into a new strategy for treating cancer and other diseases. Targeting specific histone demethylases can be challenging as the active sites of KDM1A-B and KDM-4A-D histone demethylases, respectively, are highly conserved. Most...... inhibitors developed up-to-date target either the cofactor- or substrate-binding sites of these enzymes, resulting in a lack of selectivity and off-target effects. This study describes the discovery of the first peptide-based inhibitors of KDM4 histone demethylases that do not share the histone peptide...... sequence, or inhibit through substrate competition. Through screening of DNA-encoded peptide libraries against KDM1 and -4 histone demethylases by phage display, two cyclic peptides targeting the histone demethylase KDM4C were identified and developed as inhibitors by amino acid replacement, truncation...

  8. Study of improved electrochemical performance of LiFePO4/C electrode for LIB

    Institute of Scientific and Technical Information of China (English)

    HU; Guo-rong; GAO; Xu-guang; PENG; Zhong-dong

    2005-01-01

    Lithium iron phosphate is a most promising cathode material for Li-ion batteries(LIB).But the key barrier limiting its application is extremely low electronic conductivity. Meanwhile the low electron conductivity can be improved by preparing LiFePO4 with carbon modified. LiFePO4/C was synthesized by high temperature solid-state reaction using iron (Ⅱ) oxalate, ammonium di-hydrogen phosphate and lithium carbonate with a kind of organic compound (CR) that can be dissolved in the dispersant (ethanol) as carbon sources added to the synthetic precursor in this paper.The samples were characterized by X-ray diffraction, scanning electron microscope observations,charge/discharge test, cyclic voltammetry and carbon analysis. It was believed that the synthesized LiFePO4/C with perfect olivine structure by X-ray diffraction. The carbon brought about two advantages: (i) an optimized particle size of LiFePO4, and (ii) increasing the electronic conductivity and Li+ diffusivity. The cathode material could demonstrate a charge/discharge flat voltage of 3.4V (Vs Li+/Li). Especially the active material with 20% organic added according to the final product of LiFePO4 showed very good electrochemical performance reaching about initial 162.0 mAh/g specific capacity at 0. 1C rate and could also keep excellent discharge capacity even at 3C rate (510 mA/g) current and good cycle performance. The carbon content in the final production was only 5.29%(mass fraction).

  9. Solubility of alkali metal halides in the ionic liquid [C4C1im][OTf].

    Science.gov (United States)

    Kuzmina, O; Bordes, E; Schmauck, J; Hunt, P A; Hallett, J P; Welton, T

    2016-06-28

    The solubilities of the metal halides LiF, LiCl, LiBr, LiI, NaF, NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbCl, CsCl, CsI, were measured at temperatures ranging from 298.15 to 378.15 K in the ionic liquid 1-butyl-3-methylimidazolium trifluoromethanesulfonate ([C4C1im][OTf]). Li(+), Na(+) and K(+) salts with anions matching the ionic liquid have also been investigated to determine how well these cations dissolve in [C4C1im][OTf]. This study compares the influence of metal cation and halide anion on the solubility of salts within this ionic liquid. The highest solubility found was for iodide salts, and the lowest solubility for the three fluoride salts. There is no outstanding difference in the solubility of salts with matching anions in comparison to halide salts. The experimental data were correlated employing several phase equilibria models, including ideal mixtures, van't Hoff, the λh (Buchowski) equation, the modified Apelblat equation, and the non-random two-liquid model (NRTL). It was found that the van't Hoff model gave the best correlation results. On the basis of the experimental data the thermodynamic dissolution parameters (ΔH, ΔS, and ΔG) were determined for the studied systems together with computed gas phase metathesis parameters. Dissolution depends on the energy difference between enthalpies of fusion and dissolution of the solute salt. This demonstrates that overcoming the lattice energy of the solid matrix is the key to the solubility of inorganic salts in ionic liquids. PMID:27264676

  10. Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.

    Directory of Open Access Journals (Sweden)

    Cheryl Carson

    Full Text Available Englerin A is a structurally unique natural product reported to selectively inhibit growth of renal cell carcinoma cell lines. A large scale phenotypic cell profiling experiment (CLiP of englerin A on ¬over 500 well characterized cancer cell lines showed that englerin A inhibits growth of a subset of tumor cell lines from many lineages, not just renal cell carcinomas. Expression of the TRPC4 cation channel was the cell line feature that best correlated with sensitivity to englerin A, suggesting the hypothesis that TRPC4 is the efficacy target for englerin A. Genetic experiments demonstrate that TRPC4 expression is both necessary and sufficient for englerin A induced growth inhibition. Englerin A induces calcium influx and membrane depolarization in cells expressing high levels of TRPC4 or its close ortholog TRPC5. Electrophysiology experiments confirmed that englerin A is a TRPC4 agonist. Both the englerin A induced current and the englerin A induced growth inhibition can be blocked by the TRPC4/C5 inhibitor ML204. These experiments confirm that activation of TRPC4/C5 channels inhibits tumor cell line proliferation and confirms the TRPC4 target hypothesis generated by the cell line profiling. In selectivity assays englerin A weakly inhibits TRPA1, TRPV3/V4, and TRPM8 which suggests that englerin A may bind a common feature of TRP ion channels. In vivo experiments show that englerin A is lethal in rodents near doses needed to activate the TRPC4 channel. This toxicity suggests that englerin A itself is probably unsuitable for further drug development. However, since englerin A can be synthesized in the laboratory, it may be a useful chemical starting point to identify novel modulators of other TRP family channels.

  11. VLBI Measurements of Plasma Turbulence Associated with the Cygnus OB1 Association

    Science.gov (United States)

    Spangler, Steven R.; Cordes, James M.

    1998-10-01

    We have made dual-frequency (1.67 and 5.00 GHz) VLBI observations of five compact, presumably extragalactic radio sources in the Galactic plane in the constellation of Cygnus. The lines of sight to these sources pass through a part of the interstellar medium that is modified by the Cygnus OB1 association. The VLBI observations were processed to yield measurements of the scattering measure due to interstellar plasma turbulence. The dual-frequency VLBI observations allowed estimates of the possible intrinsic structure contamination of the scattering measurements. Such an error is estimated to be less than 5% of the scattering measure for our two best-observed cases, and 15% to as high as 30% for a more weakly scattered source. Modeling the spatial power spectrum of the turbulence by Pδn(q) = C2Nq-α, where q is the spatial wavenumber of the turbulent fluctuations, our observations provide a measurement of 0LC2Ndz, where L is the thickness of the scattering medium and z is a coordinate along the line of sight. When combined with our earlier observations of the radio source 2013+370, we have a total of six lines of sight through the Cygnus OB1 association. Our observations show that the scattering through the Cygnus OB1 association is heavy and that the scattering measures vary from 0.14 to 2.21 m-20/3 kpc on lines of sight separated by as little as 1°-2°. When combined with measurements of the emission measure in the same directions, our scattering-measure results constrain properties of the turbulence in the Cygnus OB1 association. Specifically, if ε is the normalized amplitude of the density fluctuations, and l0 is the outer scale to the Kolmogorov spectrum, then our combined scattering measure-emission measure data set constrains the quantity ε2/(1+ε2)l2/30. The mean value is ~4.3 × 10-13 cm-2/3, with a range of about 0.5 in the logarithm. We do not have sufficient information to determine ε and l0 separately, but plausible ranges are ε < 1 and l0 < 3 pc

  12. Purification and physical-chemical properties of methanobactin: a chalkophore from Methylosinus trichosporium OB3b.

    Science.gov (United States)

    Kim, Hyung J; Galeva, Nadezhda; Larive, Cynthia K; Alterman, Michail; Graham, David W

    2005-04-01

    Methanobactin is an extracellular, copper-binding chromopeptide from the methane-oxidizing bacterium, Methylosinus trichosporium OB3b, believed to be involved in copper detoxification, sequestration, and uptake. Although small (1217.2 Da), methanobactin possesses a complex three-dimensional macrocyclic structure with several unusual moieties. The molecule binds one copper and has the N-2-isopropylester-(4-thionyl-5-hydroxyimidazolate)-Gly(1)-Ser(2)-Cys(3)-Tyr(4)-pyrrolidine-(4-hydroxy-5-thionylimidazolate)-Ser(5)-Cys(6)-Met(7) sequence [Kim, H. J., et al. (2004) Science 305, 1612-1615]. We report methods for purifying methanobactin from M. trichosporium OB3b and present initial evidence of its physiological function. MALDI-TOF MS was used to systematically monitor samples for optimizing purification conditions, and for detecting and analyzing specific metal-methanobactin complexes. Purification was performed by first stabilizing the extracted compound with copper followed by separation using reversed-phase HPLC in neutral pH buffers. Purified methanobactin exhibited UV-visible maxima at 342 nm, a shoulder at 388 nm, and a broad peak at 282 nm. These features were lost upon CuCl(2) titration with appearance of new features at 335, 356, 290, and 255 nm. Furthermore, methanobactin contains two fluorescent moieties, which exhibit broad emissions at 440-460 nm (lambda(max)(ex) at 388 nm) and 390-430 nm (lambda(max)(ex) = 342 nm), respectively. Finally, methanobactin eliminates the growth lag in M. trichosporium OB3b and substantially increases growth rates when cultures are exposed to elevated copper levels. PMID:15794651

  13. Winds of low-metallicity OB-type stars: HST-COS spectroscopy in IC 1613

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, Miriam; Najarro, Francisco [Centro de Astrobiología, CSIC-INTA. Ctra. Torrejón a Ajalvir km.4, E-28850 Torrejón de Ardoz, Madrid (Spain); Herrero, Artemio [Instituto de Astrofísica de Canarias. Vía Láctea s/n, E-38200 La Laguna (S. C. Tenerife) (Spain); Lennon, Daniel J. [European Space Astronomy Centre, Camino Bajo del Castillo, E-28692 Villanueva de la Cañada, Madrid (Spain); Urbaneja, Miguel Alejandro [Institute for Astro- and Particle Physics, University of Innsbruck, Technikerstr. 25/8, A-6020 Innsbruck (Austria)

    2014-06-10

    We present the first quantitative ultraviolet spectroscopic analysis of resolved OB stars in IC 1613. Because of its alleged very low metallicity (≲1/10 Z {sub ☉}, from H II regions), studies in this Local Group dwarf galaxy could become a significant step forward from the Small Magellanic Cloud (SMC) toward the extremely metal-poor massive stars of the early universe. We present HST-COS data covering the ∼1150-1800 Å wavelength range with resolution R ∼ 2500. We find that the targets do exhibit wind features, and these are similar in strength to SMC stars. Wind terminal velocities were derived from the observed P Cygni profiles with the Sobolev plus Exact Integration method. The v {sub ∞}-Z relationship has been revisited. The terminal velocity of IC 1613 O stars is clearly lower than Milky Way counterparts, but there is no clear difference between IC 1613 and SMC or LMC analog stars. We find no clear segregation with host galaxy in the terminal velocities of B-supergiants, nor in the v {sub ∞}/v {sub esc} ratio of the whole OB star sample in any of the studied galaxies. Finally, we present the first evidence that the Fe-abundance of IC 1613 OB stars is similar to the SMC, which is in agreement with previous results on red supergiants. With the confirmed ∼1/10 solar oxygen abundances of B-supergiants, our results indicate that IC 1613's α/Fe ratio is sub-solar.

  14. Perception oro-sensorielle des lipides alimentaires et obésité

    Directory of Open Access Journals (Sweden)

    Besnard Philippe

    2016-05-01

    Full Text Available La gustation est un système dynamique capable d’une adaptation physiologique rapide en réponse aux changements environnementaux permanents qui caractérisent notre alimentation (rythme, qualité, quantité. Basé sur la modulation des seuils de sensibilité gustative, ce système homéostatique contribue à la construction du comportement alimentaire en orientant les choix de consommation. On peut donc penser qu’un dysfonctionnement de ce système régulateur peut avoir un impact sur les habitudes alimentaires et donc, à terme, sur la santé. La mise en évidence récente chez le rongeur (rat, souris qu’une obésité induite par le régime non seulement entraîne une détérioration de la détection orale des lipides mais se traduit également par une préférence accrue pour le «gras», plaide en faveur de cette thèse. Chez l’homme, nos travaux indiquent que les sujets obèses, dont la détection oro-sensorielle des lipides est défectueuse, surconsomment des aliments riches en graisse. Ces données murines et humaines suscitent une question fondamentale : quel est le lien entre lipides, obésité et désordres gustatifs? Cette mini-revue se propose de faire le point des connaissances actuelles sur ce sujet.

  15. ObsPy: A Python toolbox for seismology - Current state, applications, and ecosystem around it

    Science.gov (United States)

    Lecocq, Thomas; Megies, Tobias; Krischer, Lion; Sales de Andrade, Elliott; Barsch, Robert; Beyreuther, Moritz

    2016-04-01

    ObsPy (http://www.obspy.org) is a community-driven, open-source project offering a bridge for seismology into the scientific Python ecosystem. It provides * read and write support for essentially all commonly used waveform, station, and event metadata formats with a unified interface, * a comprehensive signal processing toolbox tuned to the needs of seismologists, * integrated access to all large data centers, web services and databases, and * convenient wrappers to third party codes like libmseed and evalresp. Python, in contrast to many other languages and tools, is simple enough to enable an exploratory and interactive coding style desired by many scientists. At the same time it is a full-fledged programming language usable by software engineers to build complex and large programs. This combination makes it very suitable for use in seismology where research code often has to be translated to stable and production ready environments. It furthermore offers many freely available high quality scientific modules covering most needs in developing scientific software. ObsPy has been in constant development for more than 5 years and nowadays enjoys a large rate of adoption in the community with thousands of users. Successful applications include time-dependent and rotational seismology, big data processing, event relocations, and synthetic studies about attenuation kernels and full-waveform inversions to name a few examples. Additionally it sparked the development of several more specialized packages slowly building a modern seismological ecosystem around it. This contribution will give a short introduction and overview of ObsPy and highlight a number of use cases and software built around it. We will furthermore discuss the issue of sustainability of scientific software.

  16. Nature vs. Nurture: The influence of OB star environments on proto-planetary disk evolution.

    Science.gov (United States)

    Bouwman, Jeroen; Feigelson, Eric; Getman, Kostantin; Henning, Thomas; Lawson, Warrick; Linz, Hendrik; Luhman, Kevin; Roccatagliata, Veronica; Sicilia Aguilar, Aurora; Townsley, Leisa; Wang, Junfeng

    2006-05-01

    A natural approach for understanding the origin and diversity of planetary systems is to study the birth sites of planetary systems under varying environmental conditions. Dust grains in protoplanetary disks, the building blocks of planets, are structurally and chemically altered, and grow through coagulation into planetesimals. The disk geometry may change from a flaring to a more flattened structure, gaps may develop under the gravitational influence of protoplanets, and eventually the disk will dissipate, terminating the planet formation process. While the infrared properties of disks in quiet cloud environments have been extensively studied, investigations under the conditions of strong UV radiation and stellar winds in the proximity of OB stars have been limited. We propose a combined IRAC/IRS study of a large, well-defined and unbiased X-ray selected sample of pre-main-sequence stars in three OB associations: Pismis 24 in NGC 6357, NGC 2244 in the Rosette Nebula, and IC 1795 in the W3 complex. The samples are based on recent Chandra X-ray Observatory studies which reliably identify hundreds of cluster members and were carefully chosen to avoid high infrared nebular background. A new Chandra exposure of IC 1795 is requested, and an optical followup to characterise the host stars is planned. Modelling the Spitzer findings will provide the composition and size of dust present as well as the geometry, mass, and gaps in the global structure of the disk. As hundreds of cluster members will be covered with IRAC and dozens with IRS, good statistics on the disk evolution and dispersal as a function of location with respect to OB stars will be obtained. Comparison of disk properties within our sample and with existing Spitzer studies of quiescent star-forming regions should significantly advance the aim of characterising the influence of the environment on the evolution of protoplanetary disks. This effort relies on a powerful synergy between the Chandra and Spitzer

  17. CONSTRAINTS ON THE MAGELLANIC CLOUDS' INTERACTION FROM THE DISTRIBUTION OF OB STARS AND THE KINEMATICS OF GIANTS

    International Nuclear Information System (INIS)

    Young, OB-type candidates are identified in a ∼7900 deg2 region encompassing the Large and Small Magellanic Clouds (LMC/SMC) periphery, the Bridge, part of the Magellanic Stream (MS), and Leading Arm (LA). Selection is based on UV, optical, and IR photometry from existing large-area surveys and proper motions from the Southern Proper Motion 4 (SPM4) catalog. The spatial distribution of these young star candidates shows (1) a well-populated SMC wing which continues westward with two branches partially surrounding the SMC, (2) a rather narrow path from the SMC wing eastward toward the LMC which is offset by 1°-2° from the high-density H I ridge in the Bridge, (3) a well-populated periphery of the LMC dominated by clumps of stars at the ends of the LMC bar, and (4) a few scattered candidates in the MS and two overdensities in the LA regions above and below the Galactic plane. Additionally, a proper-motion analysis is made of a radial-velocity-selected sample of red giants and supergiants in the LMC, previously shown to be a kinematically and chemically distinct subgroup, most likely captured from the SMC. SPM4 proper motions of these stars also indicate they are distinct from the LMC population. The observational results presented here, combined with the known orbits of the Clouds and other aspects of the LMC morphology, suggest an off-center, moderate to highly inclined collision between the SMC and the LMC's disk that took place between 100 and 200 Myr ago.

  18. DOSTOJANSTVO BOLNIKA OB KONCU ŽIVLJENJA: PRAVNI VIDIKI IN ETIČNE DILEME

    OpenAIRE

    Ham Kacin, Klavdija

    2013-01-01

    Medicinske sestre imajo pomembno nalogo za ohranjanje dostojanstva pri pacientih v zadnjih dneh življenja in za njihovo dostojanstveno smrt. Za ohranjanje dostojanstva neozdravljivo bolnega in umirajočega pacienta naj bi zdravstvena nega zajemala širok spekter aktivnosti, ki vplivajo na odpravo ali zmanjšanje dejavnikov, ki lahko zmanjšajo pacientov občutek dostojanstva. Za uspešno ohranjanje dostojanstva je pomembno dobro poznavanje pravnih vidikov, pravic pacientov v zadnjem obdobju življen...

  19. Cyg OB2 #5: When three stars are just not enough

    OpenAIRE

    Kennedy, M; Dougherty, S. M.; P.M. Williams; Fink, A.

    2010-01-01

    Archival observations from the Very Large Array (VLA) at frequencies between 1.4 GHz and 43 GHz of the 6.6-day O6.5-7+O5.5-6 binary Cyg OB2 #5 over 20 years are re-examined. The aim is to determine the location and character of its known variable radio emission. The radio emission consists of a primary component associated with the binary, and a non-thermal source (NE), $0.8" to the NE. This work reveals that NE shows no evidence of variation demonstrating that the variable emission arises in...

  20. Modelling the radio emission from Cyg OB2 #5: a quadruple system?

    OpenAIRE

    Kennedy, M; Dougherty, S. M.; P.M. Williams; Fink, A.

    2009-01-01

    Fifty archival radio observations of the supergiant binary Cyg OB2 #5 using the Very Large Array over 20 years are re-examined to determine the location and character of the previously detected variable radio emission. The radio emission from the system consists of a primary component that is associated with the binary, and a non-thermal source (NE) that has been ascribed to a wind-collision region (WCR) between the stellar winds of the binary and that of a B-type star (Star D) to the NE. NE ...

  1. Posredovanje gasilcev ob ekološki nesreči

    OpenAIRE

    Erjavec, Gregor

    2016-01-01

    Slovenija je zaradi svoje geografske lege izpostavljena številnim naravnim in drugim nesrečam. Zaradi vse večjega in hitrejšega razvoja tehnologije in industrializacije se na svetu pojavljajo nove oblike nevarnih snovi, ki ob nenadzorovanem transportu, skladiščenju ali uporabi povzročijo t. i. ekološko nesrečo, ki ima lahko tudi katastrofalne posledice. Slovenija ima za varstvo pred nesrečami vzpostavljeno Upravo Republike Slovenije za zaščito in reševanje, ki razpolaga z ogromno enotami, ki ...

  2. SISTEMIZACIJA DELOVNIH MEST V PODJETJU VIGIT D.O.O. ZAGORJE OB SAVI

    OpenAIRE

    Podlesnik, Dunja

    2010-01-01

    V Zakonu o delovnih razmerjih je določeno, da mora delodajalec s splošnim aktom določiti pogoje za opravljanje dela na posameznem delovnem mestu oziroma za vrsto dela. Ta obveznost se sicer ne nanaša na manjše delodajalce, vendar smo se v podjetju Vigit d.o.o. Zagorje ob Savi odločili, da pripravimo učinkovit in pregleden pravilnik o organizaciji in sistemizaciji delovnih mest. Menimo namreč, da bo to prispevalo k boljšemu delu na kadrovskem področju in nasploh k doseganju poslovnih cilj...

  3. KARIERNE ZMOŽNOSTI MLADEGA DIPLOMANTA OB VSTOPU NA TRG DELA V 21. STOLETJU

    OpenAIRE

    Šalamun, Nina

    2016-01-01

    V diplomskem delu smo skušali prikazati karierne zmožnosti mladih diplomantov ob vstopu na trg dela v 21. stoletju. Opisali smo teoretična spoznanja o karieri in kako so se ta spreminjala skozi zgodovino. Izpostavili smo teorijo kariernih sider, ki jo teoretiki ocenjujejo za najbolj celovito, in opisali nove vzorce karier, ki so se pojavili zaradi tržnih in ekonomskih sprememb. Prikazali smo, kakšna znanja in kompetence so potrebni današnjim diplomantom na trgu delovne sile in kakšen j...

  4. Non-LTE Abundances of Magnesium, Aluminum and Sulfur in OB Stars Near the Solar Circle

    OpenAIRE

    Daflon, S.; Cunha, K.; Smith, V.V.; Butler, K.

    2002-01-01

    Non-LTE abundances of magnesium, aluminum and sulfur are derived for a sample of 23 low-v \\sin i stars belonging to six northern OB associations of the Galactic disk within 1 kpc of the Sun. The abundances are obtained from the fitting of synthetic line profiles to high resolution spectra. A comparison of our results with HII region abundances indicates good agreement for sulfur while the cepheid abundances are higher. The derived abundances of Mg show good overlap with the cepheid results. T...

  5. Excellent Temperature Performance of Spherical LiFePO4/C Composites Modified with Composite Carbon and Metal Oxides

    OpenAIRE

    2014-01-01

    Nanosized spherical LiFePO4/C composite was synthesized from nanosized spherical FePO4 ·2H2O, Li2C2O4, aluminum oxide, titanium oxide, oxalic acid, and sucrose by binary sintering process. The phases and morphologies of LiFePO4/C were characterized using SEM, TEM, CV, EIS, EDS, and EDX as well as charging and discharging measurements. The results showed that the as-prepared LiFePO4/C composite with good conductive webs from nanosized spherical FePO4 ·2H2O exhibits excellent electrochemical pe...

  6. Comparing the Electrochemical Performance of LiFePO4/C Modified by Mg Doping and MgO Coating

    OpenAIRE

    Jianjun Song; Ying Zhang; Guangjie Shao

    2013-01-01

    Supervalent cation doping and metal oxide coating are the most efficacious and popular methods to optimize the property of LiFePO4 lithium battery material. Mg-doped and MgO-coated LiFePO4/C were synthesized to analyze their individual influence on the electrochemical performance of active material. The specific capacity and rate capability of LiFePO4/C are improved by both MgO coating and Mg doping, especially the Mg-doped sample—Li0.985Mg0.015FePO4/C, whose discharge capacity is up to 163 m...

  7. The 2010 Haiti earthquake sequence: new insight of the tectonic pattern from aftershocks and marine geophysical data : Haiti-OBS cruise

    Science.gov (United States)

    Mercier de Lepinay, B. F.; Mazabraud, Y.; Klingelhoefer, F.; Clouard, V.; Hello, Y.; Graindorge, D.; Marcaillou, B.; Crozon, J.; Saurel, J.; Charvis, P.; Mildor, B. S.; Deschamps, A.; Bouin, M.; Perrot, J.

    2010-12-01

    The devastating 2010 Haiti earthquake ruptured only a relatively short segment (~50km) of the Enriquillo-Plantain Garden fault (EPGF) a 600km long strike-slip fault running onland and offshore from Jamaica to Dominican Republic, with apparently no major surface rupture in the epicentral area. Considering the general behavior of such strike-slip fault (i.e. North Anatolian fault, San Andreas fault), we can expect that, following the 2010 earthquake, other large earthquakes will occur in the near future on adjacent segments. To contribute to the multinational scientific effort for a better understanding of the rupture process and the stress relaxation of this earthquake, we organized the Haiti-OBS cruise of the R/V L'Atalante few weeks after the catastrophe (Feb.5 to Feb.15, 2010, from and to Pointe-a-Pitre, Guadeloupe). Our goal was 1) to deploy a temporary network of seismologic stations -21 OBS, Ocean Bottom Seismometer, and 4 onland stations- and 2) to survey the detailed sea-floor features in relation with the deformation pattern of the area (multibeam bathymetry and mud-penetrator). We show that the distribution pattern of the aftershocks as well as the compressive surface structures observed in the geology and onshore/offshore morphology of the area are consistent with a deformation model implying a major left-lateral component along the EPGF, and a strong reverse component. The January 12, 2010 mainshock has been shown as very complex. However, in the first order, the mainshock and the distribution of the aftershocks, better localized by our temporary network, can be explained by the interaction between the strike-slip EPGF system and a blind folds-and-thrusts system. Thus, the general geological setting shows a southern extension until the southern part of the Canal du Sud area of the well-known fold and thrust system of the Hispaniola main block.

  8. Calculation of the store house worker dose in a lost wax foundry using MCNP-4C.

    Science.gov (United States)

    Alegría, Natalia; Legarda, Fernando; Herranz, Margarita; Idoeta, Raquel

    2005-01-01

    Lost wax casting is an industrial process which permits the transmutation into metal of models made in wax. The wax model is covered with a silicaceous shell of the required thickness and once this shell is built the set is heated and wax melted. Liquid metal is then cast into the shell replacing the wax. When the metal is cool, the shell is broken away in order to recover the metallic piece. In this process zircon sands are used for the preparation of the silicaceous shell. These sands have varying concentrations of natural radionuclides: 238U, 232Th and 235U together with their progenics. The zircon sand is distributed in bags of 50 kg, and 30 bags are on a pallet, weighing 1,500 kg. The pallets with the bags have dimensions 80 cm x 120 cm x 80 cm, and constitute the radiation source in this case. The only pathway of exposure to workers in the store house is external radiation. In this case there is no dust because the bags are closed and covered by plastic, the store house has a good ventilation rate and so radon accumulation is not possible. The workers do not touch with their hands the bags and consequently skin contamination will not take place. In this study all situations of external irradiation to the workers have been considered; transportation of the pallets from vehicle to store house, lifting the pallets to the shelf, resting of the stock on the shelf, getting down the pallets, and carrying the pallets to production area. Using MCNP-4C exposure situations have been simulated, considering that the source has a homogeneous composition, the minimum stock in the store house is constituted by 7 pallets, and the several distances between pallets and workers when they are at work. The photons flux obtained by MCNP-4C is multiplied by the conversion factor of Flux to Kerma for air by conversion factor to Effective Dose by Kerma unit, and by the number of emitted photons. Those conversion factors are obtained of ICRP 74 table 1 and table 17 respectively. This

  9. Cloning and expression analysis of human reticulon 4c cDNA

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    RTNs (reticulons) is a gene family related to the growth and differentiation of neuroendocrine cell. This family is composed of several members such as RTN1, RTN2 and RTN3. RTN1 and RTN2 have been proved to have 3 transcripts with different length. Because the RTN1c cDNA was involved in the sologenesis of small cell lung carcinoma (SCLC), it was selected as a bioinformatic probe to clone novel members of RTN family with the electric hybridization assistant new-gene cloning method (EHAC). A 1677-bp cDNA was identified from human brain cDNA library. The cDNA contains an intact open reading frame (ORF) which encodes a protein of 199 amino acids. This deduced protein is highly homologous to RTN1c, RTN2c and RTN3 with identities of 64.4%, 45.8% and 50.0% respectively. This new gene was named RTN4c (GenBank accession number: AF087901). Northern hybridization showed that the full length of RTN4c transcript is about 1.8 kb. It is hardly expressed in heart, placenta, lung, spleen, thymus, testis, ovary, small intestine and peripheral blood white cells; but it is highly expressed in the tissues of skeletal muscle, brain, liver and kidney, and less expressed in the pancreas, prostate and colon. Furthermore, Northern results also showed that there is a 2.3 kb transcript expressed in 14 tissues except liver and skeletal muscle; while another 5.0 kb transcript in brain, skeletal muscle and testis. By the electric hybridization walking, we obtained two full-length contigs with a length of 4632 and 2235 bp respectively. The former encodes a protein with 1192 amino acids and was defined as RTN4a; the latter encodes another protein with 373 amino acids, and was named RTN4b. The RTN4 gene was mapped to human chromosome 2p14-p13 region by the radiation hybridization (RH).

  10. Electronic structure and electrical transport characteristics of C60, 2C60 and 4C60 fullerene molecules

    Institute of Scientific and Technical Information of China (English)

    SHEN Haijun; MU Xiancai

    2007-01-01

    The extended Hückel method and the Green's function method were used to calculate the electronic struc-ture and electrical transport of Au electrode-C60,2C60 or 4C60 fullerene-Au electrode systems.Furthermore,their electronic structure and electrical transport characteristics were com-pared and analyzed.The results show that (I) owing to the contact with the Au electrodes,the C60,2C60 and 4C60 mole-cules change in their electronic structures ignificantly,and their energy gaps between LUMO and HOMO are narrow;(ii) the bonding between C60,2C60 or 4C60 fullerene and Au electrodes is partially covalent and partially electrovalent;and (iii) the conductance of the three fullerenes conforms to the order of C60>2C60>4C60.

  11. Processing and characterization of B4C/Cu graded composite as plasma facing component for fusion reactors

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A new approach for fabricating B4C/Cu graded composite by rapid self-resistance sintering under ultra-high pressure was presented, by which a near dense B4C/Cu graded composite with a compositional spectrum of 0-100% was successfully fabricated. Plasma relevant performances ofsintered B4C/Cu composite were preliminarily characterized, it is found that its chemical sputtering yield is 70% lower than that of SMF800 nuclear graphite under 2.7 keV D+ irradiation, and almost no damages after 66 shots of in situ plasma discharge in HL-1 Tokamak facility, which indicates B4C/Cu plasma facing component has a good physical and chemical sputtering resistance performance compared with nuclear graphite.

  12. Kinetic Behavior of LiFePO4/C Thin Film Cathode Material for Lithium-Ion Batteries

    OpenAIRE

    Kucinskis, G; Bajārs, G; Kleperis, J.; Smits, J.

    2010-01-01

    LiFePO4 was prepared in a solid state synthesis with various levels of carbon content. LiFePO4/C thin films were obtained via magnetron sputtering. The surface morphology and structure was examined. Electrochemical properties of LiFePO4/C were studied, by using cyclic voltammetry, chronopotentiometry and electrochemical impedance spectroscopy. Thin films acquired show a potential use as a cathode in lithium ion batteries, displaying charge capacity up to 34 mAh g-1.

  13. Fabrication of Al5083/B4C surface composite by friction stir processing and its tribological characterization

    OpenAIRE

    Narayana Yuvaraj; Sivanandam Aravindan; Vipin

    2015-01-01

    Improved surface properties with the retainment of bulk properties are necessary for a component for enhanced wear characteristics. Friction stir processing (FSP) is used to produce such surface composites. Fabrication of 5083 aluminum alloy with reinforced layers of boron carbide (B4C) through FSP was carried out. Micro and nano sized B4C particles were used as reinforcements. The friction processed surface composite layer was analyzed through optical and scanning electron microscopical stud...

  14. On the importance of the wind emission to the optical continuum of OB supergiants

    CERN Document Server

    Kraus, Michaela; Krticka, Jiri

    2008-01-01

    Thermal wind emission in the form of free-free and free-bound emission is known to show up in the infrared and radio continuum of hot and massive stars. For OB supergiants with moderate mass loss rates and a wind velocity distribution with \\beta = 0.8...1.0, no influence of the wind to the optical continuum, i.e. for \\lambda 1. For the case of a spherically symmetric, isothermal wind in local thermodynamical equilibrium (LTE) we calculate the free-free and free-bound processes and the emerging wind and total continuum spectra. We localize the generation region of the optical wind continuum and especially focus on the influence of a \\beta-type wind velocity distribution with \\beta > 1 on the formation of the wind continuum at optical wavelengths. The optical wind continuum is found to be generated within about 2 R_* which is exactly the wind region where \\beta strongly influences the density distribution. We find that for \\beta > 1, the continuum of a typical OB supergiant can indeed be contaminated with ther...

  15. 25 Orionis: A Kinematically Distinct 10 Myr Old Group in Orion OB1a

    CERN Document Server

    Briceño, C; Hernández, J; Calvet, N; Vivas, A K; Furesz, G; Szentgyorgyi, A; Briceno, Cesar; Hartmann, Lee; Hernandez, Jesus; Calvet, Nuria; Furesz, Gabor; Szentgyorgyi, Andrew

    2007-01-01

    We report here on the photometric and kinematic properties of a well defined group of nearly 200 low-mass pre-main sequence stars, concentrated within ~ 1 deg of the early-B star 25 Ori, in the Orion OB1a sub-association. We refer to this stellar aggregate as the 25 Orionis group. The group also harbors the Herbig Ae/Be star V346 Ori and a dozen other early type stars with photometry, parallaxes, and some with IR excess emission, consistent with group membership. The number of high and low-mass stars is in agreement with expectations from a standard Initial Mass Function. The velocity distribution for the young stars in 25 Ori shows a narrow peak centered at 19.7 km/s, very close to the velocity of the star 25 Ori. Our results provide new and compelling evidence that the 25 Ori group is a distinct kinematic entity, and that considerable space and velocity structure is present in the Ori OB1a sub-association. The low-mass members follow a well defined band in the color-magnitude diagram, consistent with an iso...

  16. La binaria LSS 3074 y su entorno: ?`una nueva asociación OB?

    Science.gov (United States)

    Niemela, V.; Morrell, N.; Corti, M.

    En este trabajo presentamos un nuevo análisis orbital de LSS~3074, junto con tipos espectrales y velocidades radiales de estrellas que podrían constituir con ella una nueva asociación OB. La estrella O4f LSS3074 fue descubierta como binaria espectroscópica de corto período y líneas dobles por Morrell & Niemela (1990, ASP Conf. Ser. 7, 57). Posteriormente, Haefner et~al.(1994, IBVS 3969) encontraron variaciones fotométricas, estimando una inclinación orbital entre 50o y 55o. Teniendo en cuenta la importancia de obtener valores empíricos para las masas de estrellas O tempranas, y considerando la gran dispersión existente entre los valores observados y su discrepancia con los predichos por los modelos teóricos, hemos obtenido nuevas observaciones espectroscópicas de este sistema, con el propósito de mejorar los elementos orbitales derivados en la solución preliminar. Además, como las estrellas O tempranas suelen formar parte de cúmulos y asociaciones OB, hemos llevado a cabo una investigación espectroscópica de varias estrellas tempranas que podrían estar físicamente relacionadas con LSS~3074.

  17. Magnetic field measurements and wind-line variability of OB-type stars

    CERN Document Server

    Schnerr, R S; Neiner, C; Verdugo, E; de Jong, J; Geers, V C; Wiersema, K; van Dalen, B; Tijani, A; Plaggenborg, B; Rygl, K L J

    2010-01-01

    Context. The first magnetic fields in O- and B-type stars that do not belong to the Bp-star class, have been discovered. The cyclic UV wind-line variability, which has been observed in a significant fraction of early-type stars, is likely to be related to such magnetic fields. Aims. We attempt to improve our understanding of massive-star magnetic fields, and observe twenty-five carefully-selected, OB-type stars. Methods. Of these stars we obtain 136 magnetic field strength measurements. We present the UV wind-line variability of all selected targets and summarise spectropolarimetric observations acquired using the MUSICOS spectropolarimeter, mounted at the TBL, Pic du Midi, between December 1998 and November 2004. From the average Stokes I and V line profiles, derived using the LSD method, we measure the magnetic field strengths, radial velocities, and first moment of the line profiles. Results. No significant magnetic field is detected in any OB-type star that we observed. Typical 1{\\sigma} errors are betwee...

  18. Clustering of OB-fold domains of the partner protease complexed with trimeric stomatin from Thermococcales.

    Science.gov (United States)

    Yokoyama, Hideshi; Matsui, Eriko; Hiramoto, Kana; Forterre, Patrick; Matsui, Ikuo

    2013-07-01

    The C-terminal soluble domain of stomatin operon partner protein (STOPP) of the hyperthermophilic archaeon Pyrococcus horikoshii has an oligonucleotide binding-fold (OB-fold). STOPP lacks the conserved surface residues necessary for binding to DNA/RNA. A tryptophan (W) residue is conserved instead at the molecular surface. Solvent-accessible W residues are often found at interfaces of protein-protein complexes, which suggested the possibility of self-assembling of STOPP. Protein-protein interactions among the C-terminal soluble domains of STOPP PH1510 (1510-C) were then analyzed by chemical linking and blue native polyacrylamide gel electrophoresis (BN-PAGE) methods. These results suggest that the soluble domains of STOPP could assemble into homo-oligomers. Since hexameric subcomplex I from archaeal proteasome consists of coiled-coil segments and OB-fold domains, molecular modeling of 1510-C was performed using hexameric subcomplex I as a template. Although 1510-C is a comparatively small polypeptide consisting of approximately 60 residues, numerous salt bridges and hydrophobic interactions were observed in the predicted hexamer of 1510-C, suggesting the stability of the homo-oligomeric structure. This oligomeric property of STOPP may be favorable for triplicate proteolysis of the trimer of prokaryotic stomatin. PMID:23587725

  19. Near infrared diffuse interstellar bands toward the Cygnus OB2 association

    CERN Document Server

    Hamano, Satoshi; Kondo, Sohei; Sameshima, Hiroaki; Nakanishi, Kenshi; Ikeda, Yuji; Yasui, Chikako; Mizumoto, Misaki; Matsunaga, Noriyuki; Fukue, Kei; Yamamoto, Ryo; Izumi, Natsuko; Mito, Hiroyuki; Nakaoka, Tetsuya; Kawanishi, Takafumi; Kitano, Ayaka; Otsubo, Shogo; Kinoshita, Masaomi; Kawakita, Hideyo

    2016-01-01

    We obtained the near-infrared (NIR) high-resolution ($R\\equiv\\lambda/\\Delta\\lambda\\sim20,000$) spectra of the seven brightest early-type stars in the Cygnus OB2 association for investigating the environmental dependence of diffuse interstellar bands (DIBs). The WINERED spectrograph mounted on the Araki 1.3m telescope in Japan was used to collect data. All 20 of the known DIBs within the wavelength coverage of WINERED ($0.91<\\lambda<1.36\\mu$m) were clearly detected along all lines of sight because of their high flux density in the NIR wavelength range and the large extinction. The equivalent widths (EWs) of DIBs were not correlated with the column densities of C$_2$ molecules, which trace the patchy dense component, suggesting that the NIR DIB carriers are distributed mainly in the diffuse component. On the basis of the correlations among the NIR DIBs both for stars in Cyg OB2 and stars observed previously, $\\lambda\\lambda$10780, 10792, 11797, 12623, and 13175 are found to constitute a "family", in which...

  20. Accretion and outflow in the proplyd-like objects near Cygnus OB2

    Energy Technology Data Exchange (ETDEWEB)

    Guarcello, M. G. [INAF-Osservatorio Astronomico di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Drake, J. J.; Wright, N. J. [Smithsonian Astrophysical Observatory, MS-67, 60 Garden Street, Cambridge, MA 02138 (United States); García-Alvarez, D. [Dpto. de Astrofísica, Universidad de La Laguna, E-38206 E-La Laguna, Tenerife (Spain); Kraemer, K. E. [Institute for Scientific Research, Boston College, Kenny Cottle L106B, Newton, MA 02459-1161 (United States)

    2014-09-20

    Cygnus OB2 is the most massive association within 2 kpc from the Sun, hosting hundreds of massive stars, thousands of young low mass members, and some sights of active star formation in the surrounding cloud. Recently, 10 photoevaporating proplyd-like objects with tadpole-shaped morphology were discovered in the outskirts of the OB association, approximately 6-14 pc away from its center. The classification of these objects is ambiguous, being either evaporating residuals of the parental cloud that are hosting a protostar inside or disk-bearing stars with an evaporating disk, such as the evaporating proplyds observed in the Trapezium Cluster in Orion. In this paper, we present a study based on low-resolution optical spectroscopic observations made with the Optical System for Imaging and low Resolution Integrated Spectroscopy, mounted on the 10.4 m Gran Telescopio CANARIAS, of two of these protostars. The spectrum of one of the objects shows evidence of accretion but not of outflows. In the latter object, the spectra show several emission lines indicating the presence of an actively accreting disk with outflow. We present estimates of the mass loss rate and the accretion rate from the disk, showing that the former exceeds the latter as observed in other known objects with evaporating disks. We also show evidence of a strong variability in the integrated flux observed in these objects as well as in the accretion and outflow diagnostics.

  1. Občanská věda v ornitologii

    OpenAIRE

    Voříšek, Petr; Vermouzek, Zdeněk

    2013-01-01

    Občanská věda je relativně nový termín pro taková vědecká bádání, na nichž se kromě profesionálních vědců významnou nebo rozhodující měrou podílejí i amatéři zabývající se danou problematikou ve svém volném čase. Přestože termín je nový, výzkumy podobného charakteru se prováděly a provádějí již dlouho. Právě ornitologie je jedním z oborů, kde má občanská věda dlouhou tradici a můžeme tak na řadě příkladů demonstrovat přínosy, úskalí i hlavní specifika tohoto způsobu vědeckého poznávání světa....

  2. An Adaptive Loss-Aware Flow Control Scheme for Delay-Sensitive Applications in OBS Networks

    Science.gov (United States)

    Jeong, Hongkyu; Choi, Jungyul; Mo, Jeonghoon; Kang, Minho

    Optical Burst Switching (OBS) is one of the most promising switching technologies for next generation optical networks. As delay-sensitive applications such as Voice-over-IP (VoIP) have recently become popular, OBS networks should guarantee stringent Quality of Service (QoS) requirements for such applications. Thus, this paper proposes an Adaptive Loss-aware Flow Control (ALFC) scheme, which adaptively decides on the burst offset time based on loss-rate information delivered from core nodes for assigning a high priority to delay-sensitive application traffic. The proposed ALFC scheme also controls the upper-bounds of the factors inducing delay and jitter for guaranteeing the delay and jitter requirements of delay-sensitive application traffic. Moreover, a piggybacking method used in the proposed scheme accelerates the guarantee of the loss, delay, and jitter requirements because the response time for flow control can be extremely reduced up to a quarter of the Round Trip Time (RTT) on average while minimizing the signaling overhead. Simulation results show that our mechanism can guarantee a 10-3 loss-rate under any traffic load while offering satisfactory levels of delay and jitter for delay-sensitive applications.

  3. Investigation of CygOB2 #11 (O5 Ifc) by modeling its atmosphere

    CERN Document Server

    Maryeva, Olga; Malogolovets, Eugene

    2014-01-01

    We continue the study of O-supergiants belonging to the association Cyg OB2 using moderate-resolution spectra. In this paper we present results of the modeling of the stellar atmosphere of Cyg OB2 #11. This object belongs to the spectral class Ofc, which was recently introduced and yet small in numbers. Ofc class consists of stars with normal spectra with CIII {\\lambda}{\\lambda}4647,4650,4652 emission lines of comparable intensity to those of the Of-defining lines NIII {\\lambda}{\\lambda}4634,4640,4642. We combined new spectral data obtained by the 1.5-m Russian-Turkish telescope with spectra from MAST and CASU archives and determined physical parameters of the wind and chemical composition of the stellar atmosphere using CMFGEN code. The estimated nitrogen abundance is lower than one in atmospheres of normal O-supergiants (i.e. O4-6 supergiants without additional spectral index "n" or "c") and carbon abundance is solar. Also we find an excess in silicon. We present an illustrative comparison of our modeling r...

  4. The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis.

    Science.gov (United States)

    Lim, Daniel A; Alvarez-Buylla, Arturo

    2016-05-02

    A large population of neural stem/precursor cells (NSCs) persists in the ventricular-subventricular zone (V-SVZ) located in the walls of the lateral brain ventricles. V-SVZ NSCs produce large numbers of neuroblasts that migrate a long distance into the olfactory bulb (OB) where they differentiate into local circuit interneurons. Here, we review a broad range of discoveries that have emerged from studies of postnatal V-SVZ neurogenesis: the identification of NSCs as a subpopulation of astroglial cells, the neurogenic lineage, new mechanisms of neuronal migration, and molecular regulators of precursor cell proliferation and migration. It has also become evident that V-SVZ NSCs are regionally heterogeneous, with NSCs located in different regions of the ventricle wall generating distinct OB interneuron subtypes. Insights into the developmental origins and molecular mechanisms that underlie the regional specification of V-SVZ NSCs have also begun to emerge. Other recent studies have revealed new cell-intrinsic molecular mechanisms that enable lifelong neurogenesis in the V-SVZ. Finally, we discuss intriguing differences between the rodent V-SVZ and the corresponding human brain region. The rapidly expanding cellular and molecular knowledge of V-SVZ NSC biology provides key insights into postnatal neural development, the origin of brain tumors, and may inform the development regenerative therapies from cultured and endogenous human neural precursors.

  5. The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis.

    Science.gov (United States)

    Lim, Daniel A; Alvarez-Buylla, Arturo

    2016-01-01

    A large population of neural stem/precursor cells (NSCs) persists in the ventricular-subventricular zone (V-SVZ) located in the walls of the lateral brain ventricles. V-SVZ NSCs produce large numbers of neuroblasts that migrate a long distance into the olfactory bulb (OB) where they differentiate into local circuit interneurons. Here, we review a broad range of discoveries that have emerged from studies of postnatal V-SVZ neurogenesis: the identification of NSCs as a subpopulation of astroglial cells, the neurogenic lineage, new mechanisms of neuronal migration, and molecular regulators of precursor cell proliferation and migration. It has also become evident that V-SVZ NSCs are regionally heterogeneous, with NSCs located in different regions of the ventricle wall generating distinct OB interneuron subtypes. Insights into the developmental origins and molecular mechanisms that underlie the regional specification of V-SVZ NSCs have also begun to emerge. Other recent studies have revealed new cell-intrinsic molecular mechanisms that enable lifelong neurogenesis in the V-SVZ. Finally, we discuss intriguing differences between the rodent V-SVZ and the corresponding human brain region. The rapidly expanding cellular and molecular knowledge of V-SVZ NSC biology provides key insights into postnatal neural development, the origin of brain tumors, and may inform the development regenerative therapies from cultured and endogenous human neural precursors. PMID:27048191

  6. A Spitzer View of Mon OB1 East/NGC 2264

    CERN Document Server

    Rapson, Valerie A; Gutermuth, Robert A; Megeath, S Thomas; Allen, Thomas S; Myers, Philip C; Allen, Lori E

    2014-01-01

    We present Spitzer 3.6, 4.5, 5.8, 8.0, and 24 micron images of the Mon OB1 East giant molecular cloud, which contains the young star forming region NGC 2264, as well as more extended star formation. With Spitzer data and 2MASS photometry, we identify and classify young stellar objects (YSOs) with dusty circumstellar disks and/or envelopes in Mon OB1 East by their infrared-excess emission and study their distribution with respect to cloud material. We find a correlation between the local surface density of YSOs and column density of molecular gas as traced by dust extinction that is roughly described as a power law in these quantities. NGC 2264 follows a power law index of ~2.7, exhibiting a large YSO surface density for a given gas column density. Outside of NGC 2264 where the surface density of YSOs is lower, the power law is shallower and the region exhibits a larger gas column density for a YSO surface density, suggesting the star formation is more recent. In order to measure the fraction of cloud members ...

  7. Observations of SNR CTA 1 and the Cyg OB1 region with VERITAS

    CERN Document Server

    Aliu, Ester

    2011-01-01

    The Cygnus region is a nearby very active star forming region, containing several OB associations, considered as tracers of young pulsars. Above 12 TeV, the Milagro Collaboration has reported the discovery of a very large source, MGRO J2019+37, lying towards the Cyg OB1 association, at the edge of the Cygnus region. The young and energetic pulsar PSR J2021+3651 has been proposed to power this emission. We present here the result of deep VERITAS observations of this region at energies above 650 GeV. These observations unveil extended and complex TeV emission compatible with MGRO J2019+37, likely made of multiple sources, and a clearly separated point source emission from the direction of CTB 87, a pulsar wind nebula candidate. We will also report on the detection of TeV emission from the young Galactic SNR CTA 1, likely powered by the first pulsar discovered through its gamma-ray radiation.

  8. The 2.35 year itch of Cyg OB2 #9. II. Radio monitoring

    CERN Document Server

    Blomme, R; Volpi, D; De Becker, M; Prinja, R K; Pittard, J M; Parkin, E R; Absil, O

    2012-01-01

    Cyg OB2 #9 is one of a small set of non-thermal radio emitting massive O-star binaries. The non-thermal radiation is due to synchrotron emission in the colliding-wind region. Cyg OB2 #9 was only recently discovered to be a binary system and a multi-wavelength campaign was organized to study its 2011 periastron passage. We report here on the results of the radio observations obtained in this monitoring campaign. We used the Expanded Very Large Array (EVLA) radio interferometer to obtain 6 and 20 cm continuum fluxes. The observed radio light curve shows a steep drop in flux sometime before periastron. The fluxes drop to a level that is comparable to the expected free-free emission from the stellar winds, suggesting that the non-thermal emitting region is completely hidden at that time. After periastron passage, the fluxes slowly increase. We introduce a simple model to solve the radiative transfer in the stellar winds and the colliding-wind region, and thus determine the expected behaviour of the radio light cu...

  9. Electrochemical properties of Li2 FeSiO4 /C nanocomposites prepared by sol-gel and hydrothermal methods

    Science.gov (United States)

    Kumar, Ajay; Jayakumar, O. D.; Naik, Vaman M.; Nazri, Gholam A.; Naik, Ratna

    Li2FeSiO4 is considered as potential cathode material for next generation lithium ion batteries because of its high specific theoretical capacity, low cost, and safety. However, it suffers from poor electronic conductivity and slow lithium ion diffusion in the solid phase. To address these issues, we have studied mesoporous Li2FeSiO4/C composites synthesized by sol-gel (SG) and hydrothermal (HT) methods using tri-block copolymer (P123) as carbon source and structure directing agent. The structure and morphology of the composites were characterized by XRD, SEM and TEM and the surface area and pore size distribution were measured by using N2 adsorption/desorption. Galvanostatic cycling, electrochemical impedance spectroscopy, and cyclic voltammetry were used to evaluate the electrochemical performance of the Li2FeSiO4/C composites. The Li2FeSiO4/C (HT) composites show a superior electrochemical performance compared to Li2FeSiO4/C (SG). At C/30 rate, the discharge capacity of Li2FeSiO4/C (HT) reached ~276 mAh/g in the 1.5-4.6 V window and shows better rate capability and stability at high rates. We attribute the improved electrochemical performance of Li2FeSiO4/C (HT) to its large surface area and reduced particle size. The details of the study will be presented.

  10. Characteristics of electrodeposited RE-Ni-W-B-B4C-MoS2 composite coating

    Institute of Scientific and Technical Information of China (English)

    马克毅; 郭忠诚; 朱晓云; 徐瑞东

    2003-01-01

    The high temperature oxidation resistance of RE-Ni-W-B-B4C-MoS2 composite coating, the effects of electrodeposition conditions on the morphologies of the coating and the effect of heat treatment temperature on its hardness, abrasion resistance and phase structure were investigated by using scanning electron microscope(SEM), X-ray diffractometer, microhardness tester and abrasion machine. The results show that the oxidation degree of RE-Ni-W-B-B4C-MoS2 composite coating is small when the temperature is lower than 700 ℃, but it increases sharply when the temperature is higher than 700 ℃. The hardness of RE-Ni-W-B-B4C-MoS2 composite coating increases with increasing heat treatment temperature, it comes up to the maximum value at 400 ℃,but it decreases gradually if the temperature rises continuously. The most favourable abrasion resistance was attained after RE-Ni-W-B-B4C-MoS2 composite coating being heat treated at 400 ℃. Without heat treating, it is mainly amorphous and partially crystallized, but wholly crystallized after being heat treated at 500 ℃. RE in the composite coating is in the form of CeO2 and additions of CeO2 and B4C can enhance the thermostability of RE-Ni-W-B-B4C-MoS2 composite coating.

  11. Microstructure and Dry-Sliding Wear Behavior of B4C Ceramic Particulate Reinforced Al 5083 Matrix Composite

    Directory of Open Access Journals (Sweden)

    Qian Zhao

    2016-09-01

    Full Text Available B4C ceramic particulate–reinforced Al 5083 matrix composite with various B4C content was fabricated successfully via hot-press sintering under Argon atmosphere. B4C particles presented relative high wettability, bonding strength and symmetrical distribution in the Al 5083 matrix. The hardness value, friction coefficient and wear resistance of the composite were higher than those of the Al 5083 matrix. The augment of the B4C content resulted in the increase of the friction coefficient and decrease of the wear mass loss, respectively. The 30 wt % B4C/Al 5083 composite exhibited the highest wear resistance. At a low load of 50 N, the dominant wear mechanisms of the B4C/Al 5083 composite were micro-cutting and abrasive wear. At a high load of 200 N, the dominant wear mechanisms were micro-cutting and adhesion wear associated with the formation of the delamination layer which protected the composite from further wear and enhanced the wear resistance under the condition of high load.

  12. High energy properties of the flat spectrum radio quasar 4C 50.11

    CERN Document Server

    Zhou, Jianeng; Liang, Chen; Wang, Zhongxiang

    2016-01-01

    We investigate the $\\gamma$-ray and X-ray properties of the flat spectrum radio quasar (FSRQ) \\4c50 at redshift $z= 1.517$. The {\\it Fermi} Large Area Telescope (LAT) data indicate that this source was in an active state since 2013 July. During the active period, the $\\gamma$-ray flux increased by more than a factor of three and two distinct flares were detected with the variability timescale as short as several hours. The $\\gamma$-ray spectra can be well fitted by a log-parabola. From the fitting, we find a correlation between the peak energy and spectral curvature for the $\\gamma$-ray spectra, which is the first time seen in $\\gamma$-ray emission from a blazar. The {\\it Swift} X-ray Telescope (XRT) data show that the source was variable at X-ray energies, but no evidence shows flux or spectral changes related to the $\\gamma$-ray activity. The broad-band X-ray spectrum obtained with {\\it Swift} XRT and {\\it NuSTAR} is well described by a broken PL model, with an extremely hard spectrum ($\\Gamma_{1} \\sim 0.1$...

  13. Performance of the MTR core with MOX fuel using the MCNP4C2 code.

    Science.gov (United States)

    Shaaban, Ismail; Albarhoum, Mohamad

    2016-08-01

    The MCNP4C2 code was used to simulate the MTR-22 MW research reactor and perform the neutronic analysis for a new fuel namely: a MOX (U3O8&PuO2) fuel dispersed in an Al matrix for One Neutronic Trap (ONT) and Three Neutronic Traps (TNTs) in its core. Its new characteristics were compared to its original characteristics based on the U3O8-Al fuel. Experimental data for the neutronic parameters including criticality relative to the MTR-22 MW reactor for the original U3O8-Al fuel at nominal power were used to validate the calculated values and were found acceptable. The achieved results seem to confirm that the use of MOX fuel in the MTR-22 MW will not degrade the safe operational conditions of the reactor. In addition, the use of MOX fuel in the MTR-22 MW core leads to reduce the uranium fuel enrichment with (235)U and the amount of loaded (235)U in the core by about 34.84% and 15.21% for the ONT and TNTs cases, respectively. PMID:27213809

  14. Intermittent Jet Activity in the Radio Galaxy 4C29.30?

    Energy Technology Data Exchange (ETDEWEB)

    Jamrozy, M.; /Jagiellonian U., Astron. Observ.; Konar, C.; Saikia, D.J.; /NCRA, Ganeshkhind; Stawarz, L.; /Jagiellonian U., Astron. Observ. /KIPAC, Menlo Park /SLAC; Mack,; /Bologna, Ist. Radioastronomia; Siemiginowska, A.; /Harvard-Smithsonian Ctr. Astrophys.

    2007-04-02

    We present radio observations at frequencies ranging from 240 to 8460 MHz of the radio galaxy 4C29.30 (J0840+2949) using the Giant Metrewave Radio Telescope (GMRT), the Very Large Array (VLA) and the Effelsberg telescope. We report the existence of weak extended emission with an angular size of {approx} 520 arcsec (639 kpc) within which a compact edge-brightened double-lobed source with a size of 29 arcsec (36 kpc) is embedded. We determine the spectrum of the inner double from 240 to 8460 MHz and show that it has a single power-law spectrum with a spectral index is {approx} 0.8. Its spectral age is estimated to be 33 Myr. The extended diffuse emission has a steep spectrum with a spectral index of {approx} 1.3 and a break frequency 240 MHz. The spectral age is {approx}>200 Myr, suggesting that the extended diffuse emission is due to an earlier cycle of activity. We reanalyze archival x-ray data from Chandra and suggest that the x-ray emission from the hotspots consists of a mixture of nonthermal and thermal components, the latter being possibly due to gas which is shock heated by the jets from the host galaxy.

  15. REVERSIBLE HYDROGEN STORAGE IN A LiBH{sub 4}-C{sub 60} NANOCOMPOSITE

    Energy Technology Data Exchange (ETDEWEB)

    Teprovich, J.; Zidan, R.; Peters, B.; Wheeler, J.

    2013-08-06

    Reversible hydrogen storage in a LiBH{sub 4}:C{sub 60} nanocomposite (70:30 wt. %) synthesized by solvent-assisted mixing has been demonstrated. During the solvent-assisted mixing and nanocomposite formation, a chemical reaction occurs in which the C{sub 60} cages are significantly modified by polymerization as well as by hydrogenation (fullerane formation) in the presence of LiBH{sub 4}. We have determined that two distinct hydrogen desorption events are observed upon rehydrogenation of the material, which are attributed to the reversible formation of a fullerane (C{sub 60}H{sub x}) as well as a LiBH4 species. This system is unique in that the carbon species (C{sub 60}) actively participates in the hydrogen storage process which differs from the common practice of melt infiltration of high surface area carbon materials with LiBH{sub 4} (nanoconfinment effect). This nanocomposite demonstrated good reversible hydrogen storage properties as well as the ability to absorb hydrogen under mild conditions (pressures as low as 10 bar H{sub 2} or temperatures as low as 150°C). The nanocomposite was characterized by TGA-RGA, DSC, XRD, LDI-TOF-MS, FTIR, 1H NMR, and APPI MS.

  16. The peculiar radio galaxy 4C 35.06: a case for recurrent AGN activity?

    CERN Document Server

    Shulevski, A; Barthel, P D; Murgia, M; van Weeren, R J; White, G J; Brüggen, M; Kunert-Bajraszewska, M; Jamrozy, M; Best, P N; Röttgering, H J A; Chyzy, K T; de Gasperin, F; Bîrzan, L; Brunetti, G; Brienza, M; Rafferty, D A; Anderson, J; Beck, R; Deller, A; Zarka, P; Schwarz, D; Mahony, E; Orrú, E; Bell, M E; Bentum, M J; Bernardi, G; Bonafede, A; Breitling, F; Broderick, J W; Butcher, H R; Carbone, D; Ciardi, B; de Geus, E; Duscha, S; Eislöffel, J; Engels, D; Falcke, H; Fallows, R A; Fender, R; Ferrari, C; Frieswijk, W; Garrett, M A; Grießmeier, J; Gunst, A W; Heald, G; Hoeft, M; Hörandel, J; Horneffer, A; van der Horst, A J; Intema, H; Juette, E; Karastergiou, A; Kondratiev, V I; Kramer, M; Kuniyoshi, M; Kuper, G; Maat, P; Mann, G; McFadden, R; McKay-Bukowski, D; McKean, J P; Meulman, H; Mulcahy, D D; Munk, H; Norden, M J; Paas, H; Pandey-Pommier, M; Pizzo, R; Polatidis, A G; Reich, W; Rowlinson, A; Scaife, A M M; Serylak, M; Sluman, J; Smirnov, O; Steinmetz, M; Swinbank, J; Tagger, M; Tang, Y; Tasse, C; Thoudam, S; Toribio, M C; Vermeulen, R; Vocks, C; Wijers, R A M J; Wise, M W; Wucknitz, O

    2015-01-01

    Using observations obtained with the LOw Fequency ARray (LOFAR), the Westerbork Synthesis Radio Telescope (WSRT) and archival Very Large Array (VLA) data, we have traced the radio emission to large scales in the complex source 4C 35.06 located in the core of the galaxy cluster Abell 407. At higher spatial resolution (~4"), the source was known to have two inner radio lobes spanning 31 kpc and a diffuse, low-brightness extension running parallel to them, offset by about 11 kpc (in projection). At 62 MHz, we detect the radio emission of this structure extending out to 210 kpc. At 1.4 GHz and intermediate spatial resolution (~30"), the structure appears to have a helical morphology. We have derived the characteristics of the radio spectral index across the source. We show that the source morphology is most likely the result of at least two episodes of AGN activity separated by a dormant period of around 35 Myr. The AGN is hosted by one of the galaxies located in the cluster core of Abell 407. We propose that it ...

  17. Music 4C, a multi-voiced synthesis program with instruments defined in C

    Science.gov (United States)

    Beauchamp, James W.

    2003-04-01

    Music 4C is a program which runs under Unix (including Linux) and provides a means for the synthesis of arbitrary signals as defined by the C code. The program is actually a loose translation of an earlier program, Music 4BF [H. S. Howe, Jr., Electronic Music Synthesis (Norton, 1975)]. A set of instrument definitions are driven by a numerical score which consists of a series of ``events.'' Each event gives an instrument name, start time and duration, and a number of parameters (e.g., pitch) which describe the event. Each instrument definition consists of event parameters, performance variables, initializations, and a synthesis algorithmic code. Thus, the synthetic signal, no matter how complex, is precisely defined. Moreover, the resulting sounds can be overlaid in any arbitrary pattern. The program serves as a mixer of algorithmically produced sounds or recorded sounds taken from sample files or synthesized from spectrum files. A score file can be entered by hand, generated from a program, translated from a MIDI file, or generated from an alpha-numeric score using an auxiliary program, Notepro. Output sample files are in wav, snd, or aiff format. The program is provided in the C source code for download.

  18. A simulation of a pebble bed reactor core by the MCNP-4C computer code

    Directory of Open Access Journals (Sweden)

    Bakhshayesh Moshkbar Khalil

    2009-01-01

    Full Text Available Lack of energy is a major crisis of our century; the irregular increase of fossil fuel costs has forced us to search for novel, cheaper, and safer sources of energy. Pebble bed reactors - an advanced new generation of reactors with specific advantages in safety and cost - might turn out to be the desired candidate for the role. The calculation of the critical height of a pebble bed reactor at room temperature, while using the MCNP-4C computer code, is the main goal of this paper. In order to reduce the MCNP computing time compared to the previously proposed schemes, we have devised a new simulation scheme. Different arrangements of kernels in fuel pebble simulations were investigated and the best arrangement to decrease the MCNP execution time (while keeping the accuracy of the results, chosen. The neutron flux distribution and control rods worth, as well as their shadowing effects, have also been considered in this paper. All calculations done for the HTR-10 reactor core are in good agreement with experimental results.

  19. The warm absorber in the radio-loud quasar 4C +74.26

    CERN Document Server

    Di Gesu, L

    2016-01-01

    Outflows of photoionized gas are commonly detected in the X-ray spectra of Seyfert 1 galaxies. However, the evidence for this phenomenon in broad line radio galaxies, which are analogous to Seyfert 1 galaxies in the radio-loud regime, has so far been scarce. Here, we present the analysis of the X-ray absorption in the radio-loud quasar 4C +74.26. With the aim of characterizing the kinetic and the ionization conditions of the absorbing material, we fitted jointly the XMM-Newton Reflection Grating Spectrometer (RGS) and the Chandra High Energy Transmission Grating Spectrometer (HETGS) spectra, which were taken 4 months apart. The intrinsic continuum flux did not vary significantly during this time lapse. The spectrum shows the absorption signatures (e.g., Fe-UTA, \\ion{O}{vii}, and \\ion{Ne}{vii}--\\ion{Ne}{x}) of a photoionized gas outflow ($N_{\\rm H} \\sim 3.5 \\times 10^{21} \\rm cm^{-2}$, $\\log \\xi \\sim 2.6$, $v_{\\rm out}\\sim 3600 \\, \\rm km \\, s^{-1}$) located at the redshift of source. We estimate that the gas i...

  20. The Swift Gamma-Ray Burst Host Galaxy Legacy Survey - I. Sample Selection and Redshift Distribution

    OpenAIRE

    Perley, D. A.; Krühler, T.; Schulze, S.; De Ugarte Postigo, A.; Hjorth, J.; Berger, E.; Cenko, S. B.; Chary, R.; Cucchiara, A.; Ellis, R; Fong, W.; Fynbo, J. P. U.; J. Gorosabel; Greiner, J.; Jakobsson, P.

    2015-01-01

    We introduce the Swift Gamma-Ray Burst Host Galaxy Legacy Survey ("SHOALS"), a multi-observatory high-redshift galaxy survey targeting the largest unbiased sample of long-duration gamma-ray burst (GRB) hosts yet assembled (119 in total). We describe the motivations of the survey and the development of our selection criteria, including an assessment of the impact of various observability metrics on the success rate of afterglow-based redshift measurement. We briefly outline our host galaxy obs...

  1. Možnosti turističnega razvoja v Občini Miklavž na Dravskem polju

    OpenAIRE

    Petković, Aleksandra

    2016-01-01

    Diplomska naloga obravnava možnosti turističnega razvoja v Občini Miklavž na Dravskem polju. Turizem je danes pomembna gospodarska dejavnost. Vedno več ljudi išče alternativo množičnemu turizmu, v ospredje prihaja trajnostni, zeleni turizem. Tukaj lahko svoje priložnosti iščejo male občine na podeželju, a vseeno dovolj blizu velikih mest. Ena izmed takšnih je Občina Miklavž na Dravskem polju. Ima nekaj kulturnih in naravnih znamenitosti, veliko gozdnih površin, ugodno prometno lego in zaledje...

  2. The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold

    International Nuclear Information System (INIS)

    KPN03535 is a protein unique to K. pneumoniae. The crystal structure reveals that KPN03535 represents a novel variant of the OB-fold and is likely to be a DNA-binding lipoprotein. KPN03535 (gi|152972051) is a putative lipoprotein of unknown function that is secreted by Klebsiella pneumoniae MGH 78578. The crystal structure reveals that despite a lack of any detectable sequence similarity to known structures, it is a novel variant of the OB-fold and structurally similar to the bacterial Cpx-pathway protein NlpE, single-stranded DNA-binding (SSB) proteins and toxins. K. pneumoniae MGH 78578 forms part of the normal human skin, mouth and gut flora and is an opportunistic pathogen that is linked to about 8% of all hospital-acquired infections in the USA. This structure provides the foundation for further investigations into this divergent member of the OB-fold family

  3. Ocean Basalt Simulator version 1 (OBS1): Trace element mass balance in adiabatic melting of a pyroxenite-bearing peridotite

    Science.gov (United States)

    Kimura, Jun-Ichi; Kawabata, Hiroshi

    2015-01-01

    present a new numerical trace element mass balance model for adiabatic melting of a pyroxenite-bearing peridotite for estimating mantle potential temperature, depth of melting column, and pyroxenite fraction in the source mantle for a primary ocean basalt/picrite. The Ocean Basalt Simulator version 1 (OBS1) uses a thermodynamic model of adiabatic melting of a pyroxenite-bearing peridotite with experimentally/thermodynamically parameterized liquidus-solidus intervals and source mineralogy. OBS1 can be used to calculate a sequence of adiabatic melting with two melting models, including (1) melting of peridotite and pyroxenite sources with simple mixing of their fractional melts (melt-melt mixing model), and (2) pyroxenite melting, melt metasomatism in the host peridotite, and melting of the metasomatized peridotite (source-metasomatism model). OBS1 can be used to explore (1) the fractions of peridotite and pyroxenite, (2) mantle potential temperature, (3) pressure of termination of melting, (4) degree of melting, and (5) residual mode of the sources. In order to constrain these parameters, the model calculates a mass balance for 26 incompatible trace elements in the sources and in the generated basalt/picrite. OBS1 is coded in an Excel spreadsheet and runs with VBA macros. Using OBS1, we examine the source compositions and conditions of the mid-oceanic ridge basalts, Loihi-Koolau basalts in the Hawaiian hot spot, and Jurassic Shatsky Rise and Mikabu oceanic plateau basalts and picrites. The OBS1 model shows the physical conditions, chemical mass balance, and amount of pyroxenite in the source peridotite, which are keys to global mantle recycling.

  4. Effect of microstructure on low temperature electrochemical properties of LiFePO4/C cathode material

    International Nuclear Information System (INIS)

    Graphical abstract: The low temperature performance of Li-ion batteries and LiFePO4/C composites was discussed. A conclusion that cathode material is the main limitation for the low temperature performance was come up, by comparing the low temperature performance of 18650 Li-ion batteries with LiMn2O4, LiNi1/3Co1/3Mn1/3O2 and LiFePO4/C as cathode materials. The low temperature performance results indicate the LiFePO4/C microstructure is the main factor influencing the low temperature performance of LiFePO4. A new LiFePO4/C with pomegranate-like spherical structure was proposed in this paper, which shows superior low temperature performance, which can be attributed to its uniform fine primary particles and smaller primary particles. - Highlights: • Low temperature performance of Li-ion battery and LiFePO4/C composite was discussed. • Cathode material mainly decided the low temperature performance of Li-ion battery. • LiFePO4/C microstructure mainly affects its low temperature performance. • Pomegranate-like spherical structure LiFePO4/C has good low temperature performance. - Abstract: The low-temperature electrochemical performance of Li-ion batteries is mainly determined by the choice of cathode material, as evident from a comparison of the low-temperature electrochemical performance of the 18650 batteries with the LiMn2O4, LiNi1/3Co1/3Mn1/3O2, and LiFePO4/C as the cathode, respectively, at −20 °C. LiFePO4/C materials with different morphologies and microstructures were prepared by different methods. The samples were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), galvanostatic charge–discharge measurements and EIS. The low-temperature performance of the samples and those of the coin cells utilizing the materials as cathodes were measured. The results indicate that the microstructure of LiFePO4/C is a key factor determining the low-temperature performance of LiFePO4/C. A new type of

  5. The peculiar radio galaxy 4C 35.06: a case for recurrent AGN activity?

    Science.gov (United States)

    Shulevski, A.; Morganti, R.; Barthel, P. D.; Murgia, M.; van Weeren, R. J.; White, G. J.; Brüggen, M.; Kunert-Bajraszewska, M.; Jamrozy, M.; Best, P. N.; Röttgering, H. J. A.; Chyzy, K. T.; de Gasperin, F.; Bîrzan, L.; Brunetti, G.; Brienza, M.; Rafferty, D. A.; Anderson, J.; Beck, R.; Deller, A.; Zarka, P.; Schwarz, D.; Mahony, E.; Orrú, E.; Bell, M. E.; Bentum, M. J.; Bernardi, G.; Bonafede, A.; Breitling, F.; Broderick, J. W.; Butcher, H. R.; Carbone, D.; Ciardi, B.; de Geus, E.; Duscha, S.; Eislöffel, J.; Engels, D.; Falcke, H.; Fallows, R. A.; Fender, R.; Ferrari, C.; Frieswijk, W.; Garrett, M. A.; Grießmeier, J.; Gunst, A. W.; Heald, G.; Hoeft, M.; Hörandel, J.; Horneffer, A.; van der Horst, A. J.; Intema, H.; Juette, E.; Karastergiou, A.; Kondratiev, V. I.; Kramer, M.; Kuniyoshi, M.; Kuper, G.; Maat, P.; Mann, G.; McFadden, R.; McKay-Bukowski, D.; McKean, J. P.; Meulman, H.; Mulcahy, D. D.; Munk, H.; Norden, M. J.; Paas, H.; Pandey-Pommier, M.; Pizzo, R.; Polatidis, A. G.; Reich, W.; Rowlinson, A.; Scaife, A. M. M.; Serylak, M.; Sluman, J.; Smirnov, O.; Steinmetz, M.; Swinbank, J.; Tagger, M.; Tang, Y.; Tasse, C.; Thoudam, S.; Toribio, M. C.; Vermeulen, R.; Vocks, C.; Wijers, R. A. M. J.; Wise, M. W.; Wucknitz, O.

    2015-07-01

    Using observations obtained with the LOw Fequency ARray (LOFAR), the Westerbork Synthesis Radio Telescope (WSRT) and archival Very Large Array (VLA) data, we have traced the radio emission to large scales in the complex source 4C 35.06 located in the core of the galaxy cluster Abell 407. At higher spatial resolution (~ 4″), the source was known to have two inner radio lobes spanning 31 kpc and a diffuse, low-brightness extension running parallel to them, offset by about 11 kpc (in projection). At 62 MHz, we detect the radio emission of this structure extending out to 210 kpc. At 1.4 GHz and intermediate spatial resolution (~ 30″), the structure appears to have a helical morphology. We have derived the characteristics of the radio spectral index across the source. We show that the source morphology is most likely the result of at least two episodes of AGN activity separated by a dormant period of around 35 Myr. The outermost regions of radio emission have a steep spectral index (α< - 1), indicative of old plasma. We connect the spectral index properties of the resolved source structure with the integrated fluxdensity spectral index of 4C 35.06 and suggest an explanation for its unusual integrated flux density spectral shape (a moderately steep power law with no discernible spectral break), possibly providing a proxy for future studies of more distant radio sources through inferring their detailed spectral index properties and activity history from their integrated spectral indices. The AGN is hosted by one of the galaxies located in the cluster core of Abell 407. We propose that it is intermittently active as it moves in the dense environment in the cluster core. In this scenario, the AGN turned on sometime in the past, and has produced the helical pattern of emission, possibly a sign of jet precession/merger during that episode of activity. Using LOFAR, we can trace the relic plasma from that episode of activity out to greater distances from the core than ever

  6. Posodobitev logistične infrastrukture v občini Radenci : diplomsko delo univerzitetnega študija

    OpenAIRE

    Kranjc, Alen

    2011-01-01

    Diplomsko delo predstavlja raziskovalno delo na področju logistične infrastrukture v Občini Radenci, ki ima velik potencial v razvoju gospodarstva in turizma. S teoretičnim delom in raziskavo smo izpolnili cilje, ki smo si jih zastavili v uvodnem delu diplomske naloge ter predstavili kako bi z optimalnimi rešitvami na področju logistične infrastrukture v občini lahko posodobili in nudili oporo gospodarstvu in turizmu. Raziskava kaže, da vlada nezadovoljstvo z obstoječo logistič...

  7. The warm absorber in the radio-loud quasar 4C +74.26

    Science.gov (United States)

    Di Gesu, L.; Costantini, E.

    2016-10-01

    Outflows of photoionized gas are commonly detected in the X-ray spectra of Seyfert 1 galaxies. However, the evidence for this phenomenon in broad line radio galaxies, which are analogous to Seyfert 1 galaxies in the radio-loud regime, has so far been scarce. Here, we present the analysis of the X-ray absorption in the radio-loud quasar 4C +74.26. With the aim of characterizing the kinetic and the ionization conditions of the absorbing material, we fitted jointly the XMM-Newton Reflection Grating Spectrometer (RGS) and the Chandra High Energy Transmission Grating Spectrometer (HETGS) spectra, which were taken 4 months apart. The intrinsic continuum flux did not vary significantly during this time lapse. The spectrum shows the absorption signatures (e.g., Fe-UTA, O vii, and Ne vii-Ne x) of a photoionized gas outflow (NH ~ 3.5 × 1021 cm-2, log ξ ~ 2.6, vout ~ 3600 km s-1) located at the redshift of source. We estimate that the gas is located outside the broad line region but within the boundaries of the putative torus. This ionized absorber is consistent with the X-ray counterpart of a polar scattering outflow reported in the optical band for this source. The kinetic luminosity carried by the outflow is insufficient to produce a significant feedback is this quasar. Finally, we show that the heavy soft X-ray absorption that was noticed in the past for this source arises mostly in the Galactic interstellar medium.

  8. Microstructure and mechanical properties of pulsed electric current sintered B4C-TiB2 composites

    International Nuclear Information System (INIS)

    Research highlights: → Fast densification of B4C-TiB2 particulate composites. → Oxide impurity removal by evaporation. → Judiciously controlled loading cycle during pulsed electric current sintering. → High strength micrometer sized B4C-TiB2 composites. - Abstract: Monolithic B4C, TiB2 and B4C-TiB2 particulate composites were consolidated without sintering additives by means of pulsed electric current sintering in vacuum. Sintering studies on B4C-TiB2 composites were carried out to reveal the influence of the pressure loading cycle during pulsed electrical current sintering (PECS) on the removal of oxide impurities, i.e. boron oxide and titanium oxide, hereby influencing the densification behavior as well as microstructure evolvement. The critical temperature to evaporate the boron oxide impurities was determined to be 2000 deg. C. Fully dense B4C-TiB2 composites were achieved by PECS for 4 min at 2000 deg. C when applying the maximum external pressure of 60 MPa after volatilization of the oxide impurities, whereas a relative density of 95-97% was obtained when applying the external pressure below 2000 deg. C. Microstructural analysis showed that B4C and TiB2 grain growth was substantially suppressed due to the pinning effect of the secondary phase and the rapid sintering cycle, resulting in micrometer sized and homogeneous microstructures. Excellent properties were obtained for the 60 vol% TiB2 composite, combining a Vickers hardness of 29 GPa, a fracture toughness of 4.5 MPa m1/2 and a flexural strength of 867 MPa, as well as electrical conductivity of 3.39E+6 S/m.

  9. Facile Hydrothermal Synthesis of Fe3O4/C Core-Shell Nanorings for Efficient Low-Frequency Microwave Absorption.

    Science.gov (United States)

    Wu, Tong; Liu, Yun; Zeng, Xiang; Cui, Tingting; Zhao, Yanting; Li, Yana; Tong, Guoxiu

    2016-03-23

    Using elliptical iron glycolate nanosheets as precursors, elliptical Fe3O4/C core-shell nanorings (NRs) [25 ± 10 nm in wall thickness, 150 ± 40 nm in length, and 1.6 ± 0.3 in long/short axis ratio] are synthesized via a one-pot hydrothermal route. The surface-poly(vinylpyrrolidone) (PVP)-protected-glucose reduction/carbonization/Ostwald ripening mechanism is responsible for Fe3O4/C NR formation. Increasing the glucose/precursor molar ratio can enhance carbon contents, causing a linear decrease in saturation magnetization (Ms) and coercivity (Hc). The Fe3O4/C NRs reveal enhanced low-frequency microwave absorption because of improvements to their permittivity and impedance matching. A maximum RL value of -55.68 dB at 3.44 GHz is achieved by Fe3O4/C NRs with 11.95 wt % C content at a volume fraction of 17 vol %. Reflection loss (RL) values (≤-20 dB) are observed at 2.11-10.99 and 16.5-17.26 GHz. Our research provides insights into the microwave absorption mechanism of elliptical Fe3O4/C core-shell NRs. Findings indicate that ring-like and core-shell nanostructures are promising structures for devising new and effective microwave absorbers. PMID:26915716

  10. Effect of gelatin concentration on the synthetize of the LiFePO4/C composite for lithium ion batteries

    International Nuclear Information System (INIS)

    Highlights: • Gelatin has been used to regulate and control the synthesis of LiFePO4/C composite. • Influence of gelatin concentration on crystal structure of LiFePO4 has been observed. • The shape transformation from sphere-like to rod-like structure of LiFePO4/C has been revealed. - Abstract: Gelatin is an effective additive of the cathode, which would regulate and control the crystal and morphology of LiFePO4/C composite for enhancing electrochemical performance of the lithium ion battery. The influence of gelatin concentration on the preparation of LiFePO4/C composite has been investigated. It is observed by SEM that the shape transformed from sphere-like to rod-like structure with the gelatin concentration increased from 1 wt.% to 5 wt.%; meanwhile, the lattice parameters first showed increase trend and then decrease. The LiFePO4/C composite obtained with the 2 wt.% gelatin solution shows the lowest polarization and excellent rate performance

  11. Preparation and performance of Nano-LiFePO4/C cathode material for lithium-ion battery

    Science.gov (United States)

    Qin, Xianzhong; Yang, Gai; Ma, Feng; Cai, Feipeng

    2016-01-01

    A high energy density LiFePO4/C material for lithium batteries was synthesized by controlled crystallization-carbothermal reaction, which has been experienced as an effective process for mass production of electrode materials. The structure and morphology of the LiFePO4/C material were characterized by X-ray diffraction and Scanning Electron Microscope (SEM). The electrochemical properties of the synthesized nano-LiFePO4/C were investigated by charge-discharge processing and cyclic voltammetry (CV). The initial discharge capacities of the LiFePO4/C battery were 163.9, 158.4, 154.5, 151.4, and 142 mA h g-1 at 0.1C, 1C, 2C, 5C, and 10C, respectively. The capacity of LiFePO4/C material maintained 98.5% at the rate of 1C after 100 cycles, demonstrating excellent rate capability and cycling performance.

  12. Facile synthesis of Fe3O4@C hollow nanospheres and their application in polluted water treatment

    Science.gov (United States)

    Zhang, Yuanguang; Xu, Shihao; Xia, Hongyu; Zheng, Fangcai

    2016-11-01

    Nanostructured carbon-based materials, such as carbon nanotube arrays have shown respectable removal ability for heavy metal ions and organic dyes in aqueous solution. Although the carbon-based materials exhibited excellent removal ability, the separation of them from the aqueous solution is difficult and time-consuming. Here we demonstrated a novel and facile route for the large-scale fabrication of Fe3O4@C hollow nanospheres, with using ferrocene as a single reagent and SiO2 as a template. The as-prepared Fe3O4@C hollow nanospheres exhibited adsorption ability for heavy metal ions and organic dyes from aqueous solution, and can be easily separated by an external magnet. When the as-prepared Fe3O4@C hollow nanospheres were mixed with the aqueous solution of Hg2+ within 15 min, the removal efficiency was 90.3%. The as-prepared Fe3O4@C hollow nanospheres were also exhibited a high adsorption capacity (100%) as the adsorbent for methylene blue (MB). In addition, the as-prepared Fe3O4@C hollow nanospheres can be used as the recyclable sorbent for water treatment via a simple magnetic separation.

  13. A formation scenario of young stellar groups in the region of the Scorpio Centaurus OB association

    CERN Document Server

    Ortega, V G; De la Reza, R; Bazzanella, B

    2009-01-01

    The main objective of this work is to investigate the role played by Lower Centaurus Crux (LCC) and Upper Centaurus Lupus (UCL), both subcomponents of the Scorpio Centaurus OB association (Sco-Cen), in the formation of the groups beta Pictoris, TW Hydrae and the eta Chamaeleontis cluster. The dynamical evolution of all the stellar groups involved and of the bubbles and shells blown by LCC and UCL are calculated and followed from the past to the present. This leads to a formation scenario in which (1) the groups beta Pictoris, TW Hydrae were formed in the wake of the shells created by LCC and UCL, (2) the young cluster eta Chamaeleontis was born as a consequence of the collision of the shells of LCC and UCL, and (3) the formation of Upper Scorpius (US), the other main subcomponent of the Sco-Cen association, may have been started by the same process that created eta Chamaeleontis.

  14. MODELING THE RADIO EMISSION FROM Cyg OB2 NO. 5: A QUADRUPLE SYSTEM?

    International Nuclear Information System (INIS)

    Fifty observations at frequencies between 1.4 GHz and 43 GHz of the 6.6 day O6.5-7+O5.5-6 binary Cyg OB2 No. 5 using the Very Large Array over 20 years are re-examined. The aim is to determine the location and character of the previously detected variable radio emission. The radio emission from the system consists of a primary component that is associated with the binary, and a non-thermal source (NE), 0.''8 to the NE of the binary that has been ascribed to a wind-collision region (WCR) between the stellar winds of the binary and that of a B-type star (Star D) to the NE. Previous studies have not accounted for the potential contribution of NE to the total radio emission, most especially in observations where the primary and NE sources are not resolved as separate sources. NE shows no evidence of variation in 23 epochs where it is resolved separately from the primary radio component, demonstrating that the variable emission arises in the primary component. Since NE is non-variable, the radio flux from the primary can now be well determined for the first time, most especially in observations that do not resolve both the primary and NE components. The variable radio emission from the primary component has a period of 6.7 ± 0.3 years which is described by a simple model of a non-thermal source orbiting within the stellar wind envelope of the binary. Such a model implies the presence of a third, unresolved stellar companion (Star C) orbiting the 6.6 day binary with a period of 6.7 years and independent of Star D to the NE. The variable non-thermal emission arises from either a WCR between Star C and the binary system, or possibly from Star C directly. The model gives a mass-loss rate of 3.4 x 10-5 Msun yr-1 for Cyg OB2 No. 5, unusually high for an Of supergiant and comparable to that of WR stars, and consistent with an unusually strong He I 1.083 μm emission line, also redolent of WR stars. An examination of radial velocity observations available from the literature

  15. OBS/GMPLS Interworking Network with Scalable Resource Discovery for Global Grid Computing

    Science.gov (United States)

    Wu, J.; Liu, L.; Hong, X. B.; Lin, J. T.

    In recent years, Grid computing is more common in the industry and research community and will open to the consumer market in the future. The final objective is the achievement of global Grid computing, which means that the computing and networks are flexibly integrated across the world and a scalable resource discovery scheme is implemented. In this paper, a promising architecture, i.e., optical burst switching (OBS)/generalized multi-protocol label switching (GMPLS) interworking network with Peer-to-Peer (P2P)-based scheme for resource discovery is investigated to realize a highly scalable and flexible platform for Grids. Experimental results show that this architecture is suitable and efficient for future global Grid computing.

  16. g4c2c: A Model for Citizen Engagement at Arms’ Length from Government

    Directory of Open Access Journals (Sweden)

    Axel Bruns

    2011-03-01

    Full Text Available Normal 0 false false false EN-AU X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The recognition that Web 2.0 applications and social media sites will strengthen and improve interaction between governments and citizens has resulted in a global push into new e-democracy or Government 2.0 spaces. These typically follow government-to-citizen (g2c or citizen-to-citizen (c2c models, but both these approaches are problematic: g2c is often concerned more with service delivery to citizens as clients, or exists to make a show of ‘listening to the public’ rather than to genuinely source citizen ideas for government policy, while c2c often takes place without direct government participation and therefore cannot ensure that the outcomes of citizen deliberations are accepted into the government policy-making process. Building on recent examples of Australian Government 2.0 initiatives, we suggest a new approach based on government support for citizen-to-citizen engagement, or g4c2c, as a workable compromise, and suggest that public service broadcasters should play a key role in facilitating this model of citizen engagement.

  17. SCUBA and HIRES Results for Protostellar Cores in the MON OB1 Dark Cloud

    Science.gov (United States)

    Wolf-Chase, G.; Moriarty-Schieven, G.; Fich, M.; Barsony, M.

    1999-05-01

    We have used HIRES-processing of IRAS data and point-source modelling techniques (Hurt & Barsony 1996; O'Linger 1997; Barsony et al. 1998), together with submillimeter continuum imaging using the Submillimeter Common-User Bolometer Array (SCUBA) on the 15-meter James Clerk Maxwell Telescope (JCMT), to search CS cores in the Mon OB1 dark cloud (Wolf-Chase, Walker, & Lada 1995; Wolf-Chase & Walker 1995) for deeply embedded sources. These observations, as well as follow-up millimeter photometry at the National Radio Astronomy Observatory (NRAO) 12-meter telescope on Kitt Peak, have lead to the identification of two Class 0 protostellar candidates, which were previously unresolved from two brighter IRAS point sources (IRAS 06382+0939 & IRAS 06381+1039) in this cloud. Until now, only one Class 0 object had been confirmed in Mon OB1; the driving source of the highly-collimated outflow NGC 2264 G (Ward-Thompson, Eiroa, & Casali 1995; Margulis et al. 1990; Lada & Fich 1996), which lies well outside the extended CS cores. One of the new Class 0 candidates may be an intermediate-mass source associated with an H_2O maser, and the other object is a low-mass source which may be associated with a near-infrared jet, and possibly with a molecular outflow. We report accurate positions for the new Class 0 candidates, based on the SCUBA images, and present new SEDs for these sources, as well as for the brighter IRAS point sources. A portion of this work was performed while GWC held a President's Fellowship from the University of California. MB and GWC gratefully acknowledge financial support from MB's NSF CAREER Grant, AST97-9753229.

  18. Distribution of global fallouts cesium-137 in taiga and tundra catenae at the Ob River basin

    Science.gov (United States)

    Semenkov, I. N.; Usacheva, A. A.; Miroshnikov, A. Yu.

    2015-03-01

    The classification of soil catenae at the Ob River basin is developed and applied. This classification reflects the diverse geochemical conditions that led to the formation of certain soil bodies, their combinations and the migration fields of chemical elements. The soil and geochemical diversity of the Ob River basin catenae was analyzed. The vertical and lateral distribution of global fallouts cesium-137 was studied using the example of the four most common catenae types in Western Siberia tundra and taiga. In landscapes of dwarf birches and dark coniferous forests on gleysols, cryosols, podzols, and cryic-stagnosols, the highest 137Cs activity density and specific activity are characteristic of the upper soil layer of over 30% ash, while the moss-grass-shrub cover is characterized by low 137Cs activity density and specific activity. In landscapes of dwarf birches and pine woods on podzols, the maximum specific activity of cesium-137 is typical for moss-grass-shrub cover, while the maximum reserves are concentrated in the upper soil layer of over 30% ash. Bog landscapes and moss-grass-shrub cover are characterized by a minimum activity of 137Cs, and its reserves in soil generally decrease exponentially with depth. The cesium-137 penetration depth increases in oligotrophic histosols from northern to middle taiga landscapes from 10-15 to 40 cm. 137Cs is accumulated in oligotrophic histosols for increases in pH from 3.3 to 4.0 and in concretionary interlayers of pisoplinthic-cryic-histic-stagnosols. Cryogenic movement, on the one hand, leads to burying organic layers enriched in 137Cs and, on the other hand, to deducing specific activity when mixed with low-active material from lower soil layers.

  19. STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function

    Science.gov (United States)

    Bhattacharjee, Anukana; Stewart, Jason; Chaiken, Mary; Price, Carolyn M.

    2016-01-01

    Mammalian CST (CTC1-STN1-TEN1) participates in multiple aspects of telomere replication and genome-wide recovery from replication stress. CST resembles Replication Protein A (RPA) in that it binds ssDNA and STN1 and TEN1 are structurally similar to RPA2 and RPA3. Conservation between CTC1 and RPA1 is less apparent. Currently the mechanism underlying CST action is largely unknown. Here we address CST mechanism by using a DNA-binding mutant, (STN1 OB-fold mutant, STN1-OBM) to examine the relationship between DNA binding and CST function. In vivo, STN1-OBM affects resolution of endogenous replication stress and telomere duplex replication but telomeric C-strand fill-in and new origin firing after exogenous replication stress are unaffected. These selective effects indicate mechanistic differences in CST action during resolution of different replication problems. In vitro binding studies show that STN1 directly engages both short and long ssDNA oligonucleotides, however STN1-OBM preferentially destabilizes binding to short substrates. The finding that STN1-OBM affects binding to only certain substrates starts to explain the in vivo separation of function observed in STN1-OBM expressing cells. CST is expected to engage DNA substrates of varied length and structure as it acts to resolve different replication problems. Since STN1-OBM will alter CST binding to only some of these substrates, the mutant should affect resolution of only a subset of replication problems, as was observed in the STN1-OBM cells. The in vitro studies also provide insight into CST binding mechanism. Like RPA, CST likely contacts DNA via multiple OB folds. However, the importance of STN1 for binding short substrates indicates differences in the architecture of CST and RPA DNA-protein complexes. Based on our results, we propose a dynamic DNA binding model that provides a general mechanism for CST action at diverse forms of replication stress. PMID:27690379

  20. Cerium regulates expression of alternative methanol dehydrogenases in Methylosinus trichosporium OB3b.

    Science.gov (United States)

    Farhan Ul Haque, Muhammad; Kalidass, Bhagyalakshmi; Bandow, Nathan; Turpin, Erick A; DiSpirito, Alan A; Semrau, Jeremy D

    2015-11-01

    Methanotrophs have multiple methane monooxygenases that are well known to be regulated by copper, i.e., a "copper switch." At low copper/biomass ratios the soluble methane monooxygenase (sMMO) is expressed while expression and activity of the particulate methane monooxygenase (pMMO) increases with increasing availability of copper. In many methanotrophs there are also multiple methanol dehydrogenases (MeDHs), one based on Mxa and another based on Xox. Mxa-MeDH is known to have calcium in its active site, while Xox-MeDHs have been shown to have rare earth elements in their active site. We show here that the expression levels of Mxa-MeDH and Xox-MeDH in Methylosinus trichosporium OB3b significantly decreased and increased, respectively, when grown in the presence of cerium but the absence of copper compared to the absence of both metals. Expression of sMMO and pMMO was not affected. In the presence of copper, the effect of cerium on gene expression was less significant, i.e., expression of Mxa-MeDH in the presence of copper and cerium was slightly lower than in the presence of copper alone, but Xox-MeDH was again found to increase significantly. As expected, the addition of copper caused sMMO and pMMO expression levels to significantly decrease and increase, respectively, but the simultaneous addition of cerium had no discernible effect on MMO expression. As a result, it appears Mxa-MeDH can be uncoupled from methane oxidation by sMMO in M. trichosporium OB3b but not from pMMO. PMID:26296730

  1. Phase Constitution in Mixed Gd2O3 and B4C by Sintering at High Temperature

    Institute of Scientific and Technical Information of China (English)

    Wu Wenyuan; Xu Jingyu; Bian Xue; Hu Guangyong; Sun Shuchen; Tu Ganfeng

    2005-01-01

    The phase constitution in mixed Gd2O3 and B4C by sintering in graphite tube furnace at the temperature of 100~1489 ℃ in argon atmosphere was studied by means of XRD and TG-DTA. The results show that the impurity C reacts with O in the B4C at the temperature of 367~458 ℃. When the temperature is 800 ℃, Gd2O3 reacts with B4C, and the reaction products include GdB6, GdB4, GdBO3, GdBC and B. GdBC changes into GdB4 at 1200 ℃. When the temperature is 1470 ℃, GdB6 is obtained by the reaction of GdB4 with elemental B. The content of GdB6 is increasing with the prolonging time.

  2. Fabrication and Properties of SiB6-B4C with Phenolic Resin as a Carbon Source

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Si-B-C ceramic composites were synthesized using SiB6, B4C, and phenolic resin as a carbon source by pressureless sintering in an Ar atmosphere. Then, the Si-B-C ceramic composites were fabricated to determine their potential for applications as high hardness and high temperature composites. The X-ray diffraction patterns of sintered bodies of SiB6-B4C with carbonized phenolic resin can be seen that SiB6 and C changed to B4C and SiC. In this study, it is obtained that carbonized phenolic resin is good addition material as a reaction material comparing to carbon powder at 1683 K for 1 h by pressureless sintering in an Ar atmosphere.

  3. Structure and characteristics of electrodeposited RE-Ni-W-P-B4C-PTFE composite coatings

    Institute of Scientific and Technical Information of China (English)

    陈凌; 郭忠诚; 杨显万

    2001-01-01

    Hardness, friction and wear characteristics of electrodeposited RE-Ni-W-P-B4C-PTFE composite coatings were studied, and the reason for these fine characteristics was explained in respect of structure. The results show that 1)the structure of RE-Ni-W-P-B4C-PTFE composite coatings experiences a transformation process from amorphous to mixture then to crystal as the heat-treatment temperature rises; 2) incorporating of B4C greatly increases the hardness of the coating; 3) the wear resistance of the coating is best with heat-treatment for 1 h at 300 ℃, which is greatly superior to that of the other traditional coatings.

  4. Characterization of Co-60 sources to the treatment of the ophthalmic tumors using the MCNP-4C code

    International Nuclear Information System (INIS)

    Ophthalmic sources used in the treatment of ophthalmic tumors needed to be periodically controlled in order to have assurance of the administrated dose in the treatment. For this purpose, an human eye was simulated with all structures and composition was simulated by MCNP-4C with an ophthalmic source of Co-60 (model CKA-4 of Amersham). With this simulator, it was possible to determine the dose in the center-eye dephness and also the doses in the structures as retina, coroide, lenses, etc. To check the doses from MCNP-4C, it was realized measurements with radiological films type X-OMAT V of Kodak, with a Co-60 CKA-4 source and an acrylic simulator. The measurement allow the construction of the optical density versus the source distance. This curve will serve as a test data for the calculated dose values of MCNP-4C. (author)

  5. Effects of leptin on in vitro maturation, fertilization and embryonic cleavage after ICSI and early developmental expression of leptin (Ob) and leptin receptor (ObR) proteins in the horse

    Science.gov (United States)

    Lange Consiglio, Anna; Dell'Aquila, Maria Elena; Fiandanese, Nadia; Ambruosi, Barbara; Cho, Yoon S; Bosi, Giampaolo; Arrighi, Silvana; Lacalandra, Giovanni M; Cremonesi, Fausto

    2009-01-01

    Background The identification of the adipocyte-derived obesity gene product, leptin (Ob), and subsequently its association with reproduction in rodents and humans led to speculations that leptin may be involved in the regulation of oocyte and preimplantation embryo development. In mice and pigs, in vitro leptin addition significantly increased meiotic resumption and promoted preimplantation embryo development in a dose-dependent manner. This study was conducted to determine whether leptin supplementation during in vitro maturation (IVM) to horse oocytes could have effects on their developmental capacity after fertilization by IntraCytoplasmic Sperm Injection (ICSI). Methods Compact and expanded-cumulus horse oocytes were matured in medium containing different concentrations (1, 10, 100, 1000 ng/ml) of recombinant human leptin and the effects on maturation, fertilization and embryo cleavage were evaluated. Furthermore, early developmental expression of Ob and leptin receptor (Ob-R) was investigated by immunocytochemical staining. Results In expanded-cumulus oocytes, the addition of leptin in IVM medium improved maturation (74% vs 44%, for 100 ng/ml leptin-treated and control groups, respectively; P < 0.05) and fertilization after ICSI (56% vs 23% for 10 ng/ml leptin-treated and control groups, respectively; P < 0.05). However, the developmental rate and quality of 8-cell stage embryos derived from leptin-treated oocytes (100 ng/ml) was significantly reduced, in contrast to previous data in other species where leptin increased embryo cleavage. Ob and Ob-R proteins were detected up to the 8-cell stage with cortical and cytoplasmic granule-like distribution pattern in each blastomere. Conclusion Leptin plays a cumulus cell-mediated role in the regulation of oocyte maturation in the mare. Species-specific differences may exist in oocyte sensitivity to leptin. PMID:19835605

  6. Preparation and electrochemical performance of LiFePO4/C microspheres by a facile and novel co-precipitation

    International Nuclear Information System (INIS)

    Graphical abstract: Display Omitted -- Highlights: •LiFePO4/C microspheres are synthesized via a facile co-precipitation in an elevated temperature oil. •PVA acts as a binder in co-precipitation reaction to restrain the free split of the droplets and promote the formation of uniform spherical precursor. •LiFePO4/C microspheres are composed of nanoparticles which are coated by a thin nano-carbon layer and imbedded into three-dimensional nano-carbon networks. •LiFePO4/C microspheres exhibit an high tap density (1.82 g cm−3), deliver large reversible discharge capacity of 106 mA h g−1 at 50C rate, and capacity retention rate over 98% after 20 cycles at various current densities. -- Abstract: LiFePO4 and LiFePO4/C microspheres are successfully synthesized via facile co-precipitation in an elevated temperature oil bath. Their morphologies and structures are investigated by X-ray diffractometer, scanning electron microscope and transmission electron microscope. LiFePO4/C microspheres are uniform between 2 and 4 μm in diameter and composed of nanoparticles from 30 to 80 nm in size. Nanoparticles are coated by a thin nano-carbon layer and imbedded into three-dimensional nano-carbon networks. LiFePO4/C microspheres exhibit a high tap density (1.82 g cm−3), deliver large reversible discharge capacity of 165 mA h g−1 at 0.1C rate, excellent rate capability of 106 mA h g−1 at 50C rate, and capacity retention over 98% after 20 cycles even applied 50C rate. Therefore, the material is a potential candidate for high-power lithium ion batteries

  7. Vliv stočení oběžného kola na charakteristiku čerpadla

    OpenAIRE

    Jelen, Richard

    2014-01-01

    Diplomová práce se zabývá změnou geometrie výstupní části oběžného kola u radiálních odstředivých čerpadel a jejímu vlivu na charakteristiku čerpadla. Při použití těchto radiálních odstředivých čerpadel v praxi je možno měnit jejich parametry na základě požadavků. Toto přizpůsobení parametrů se nazývá stočení oběžného kola. Jedná se o zmenšení průměru oběžného kola, čímž dochází ke snížení průtoku, dopravní výšky a účinnosti. Existující vztahy pro výpočet změny charakteristiky po stočení oběž...

  8. Leptin and the obesity receptor (OB-R) in the small intestine and colon: a colocalization study

    DEFF Research Database (Denmark)

    Hansen, Gert H; Niels-Christiansen, Lise-Lotte; Danielsen, E Michael

    2008-01-01

    Leptin is a hormone that plays an important role in overall body energy homeostasis, and the obesity receptor, OB-R, is widely distributed in the organism. In the intestine, a multitude of leptin actions have been reported, but it is currently unclear to what extent the hormone affects the intest......Leptin is a hormone that plays an important role in overall body energy homeostasis, and the obesity receptor, OB-R, is widely distributed in the organism. In the intestine, a multitude of leptin actions have been reported, but it is currently unclear to what extent the hormone affects...... the intestinal epithelial cells by an endocrine or exocrine signaling pathway. To elucidate this, the localization of endogenous porcine leptin and OB-R in enterocytes and colonocytes was studied. By immunofluorescence microscopy, both leptin and OB-R were mainly observed in the basolateral membrane...... activity. In contrast, coclustering occurred less frequently at the apical cell surface, and subapical endosomal localization was hardly detectable. We conclude that leptin action in intestinal epithelial cells takes place at the basolateral plasma membrane, indicating that the hormone uses an endocrine...

  9. SYNTHESIS AND CHARACTERIZATION OF LiFePO4/C PREPARED VIA A SOL–GEL METHOD

    OpenAIRE

    YAN LIN; HONGGE PAN; MINGXIA GAO; HE MIAO; SHOUQUAN LI; YUE WANG

    2008-01-01

    Carbon-coated lithium ion phosphate was synthesized from a gel precursor with ferric iron and a carbon source of organic chelating agent via a sol–gel method. The dependence of the microstructure and electrochemical performance of the synthesized LiFePO4/C on the pH value of the precursor solution during gel formation and the sintering time was investigated. The obtained LiFePO4/C particles were characterized by X-ray diffraction, field-emission scanning electron microscopy, and element analy...

  10. Synthesis of LiFePO_4/C Composite Cathode Materials Using High Surface Area Carbon as Carbon Sources

    Institute of Scientific and Technical Information of China (English)

    George; Ting-kuo; Fey; Kai-Lun; Chiang

    2007-01-01

    1 Results The pyrolyzed product of peanut shells was utilized as a carbon source to synthesize a LiFePO4/C composite.The advantages of using agricultural wastes such as peanut shells are low costs,easy processing,and environmentally benigness.Peanut shell was first treated with a porogenic agent to produce a precursor with high porosity and surface area (>2 000 m2·g-1).A small amount of precursor was mixed with LiFePO4 fine powders and heated.The optimum calcination process for synthesizing LiFePO4/C co...

  11. Effect of B sub(4)C addition on the sinterability of Al sub(2)O sub(3)

    International Nuclear Information System (INIS)

    In this paper, the densification of Al sub(2)O sub(3) pellets as a function of sintering temperature and B sub(4)C concentration has been studied. Additions of up to 15wt% B sub(4)C of two different granulometries have been considered. Sintering was carried out in a helium atmosphere in the temperature range 1400 to 1700 sup(o)C. Informations about the formation of aluminium carbide, resulting from the reaction of alumina with the graphite crucible have also been presented. (author)

  12. p73 G4C14 to A4T14 polymorphism is associated with colorectal cancer risk and survival

    Institute of Scientific and Technical Information of China (English)

    Kyung-Eun; Lee; Young-Seoub; Hong; Byoung-Gwon; Kim; Na-Young; Kim; Kyoung-Mu; Lee; Jong-Young; Kwak; Mee-Sook; Roh

    2010-01-01

    AIM:To analyze the association between the p73 G4C14-to-A4T14 polymorphism(a.k.a.,the GC/AT variation) and colorectal cancer risk and survival in the Korean population,and to evaluate the relationships between p73 polymorphism and the p73 protein expression or clinicopathological characteristics of colorectal cancer.METHODS:Three hundred and eighty-three histologically confirmed cases and 469 healthy controls,recruited at one teaching hospital in Pusan,Korea from 2001 and 2007,were genotyped for p73 G4C14-t...

  13. Rheologicai Behavior of Cationic Gemini Surfactant C18-4-C18·2Br%阳离子双子表面活性剂C18-4-C18·2Br的流变性

    Institute of Scientific and Technical Information of China (English)

    陈洪; 叶仲斌; 韩利娟; 罗平亚

    2011-01-01

    The rheological behavior of cationic Gemini surfactant ( C18-4-C18'2Br) solution and the influencing factors, such as surfactant concentration, sodium salicylate concentration and temperature, on the viscosity and viscoelasticity of the solution were investigated. The viscosity of Gemini surfactant solution increases with the increase of surfactant concentration. Both the viscosity and the viscoelasticity of Gemini surfactant solution undergo a maximum with the addition of sodium salicylate. Temperature has a significant effect on the viscosity of Gemini surfactant solution. The addition of sodium salicylate can enhance the resistance performance of Gemini surfactant solution to temperature. TEM experiments show that appropriate dosage of sodium salicylate in the Gemini surfactant solution can lead to the transition of surfactant micelles from spherical micelles to wormlike micelles. However, overmuch addition of sodium salicylate will bring about the formation of vesicles in the Gemini surfactant solution.%对阳离子双子表面活性剂四亚甲基-1,2-双(十八烷基二甲基烷基溴化铵)( C18-4-C18·2Br)的流变特性进行了研究,考察了表面活性剂质量分数、水杨酸钠质量分数及温度对表面活性剂溶液黏度和黏弹性的影响.C18-4-C18·2Br溶液的黏度随着质量分数的增加而增加.随着水杨酸钠质量分数的增加,C18-4-C18·2Br溶液的黏度和黏弹性出现先增加后下降的过程.温度对C18-4-C18 ·2Br溶液的黏度有较大影响,水杨酸钠的加入可明显提高C18-4-C18·2Br溶液的抗温性.TEM结果表明,适量的水杨酸钠能够促进C18-4-C18·2Br胶束从球形向蠕虫状转变,过量的水杨酸钠又会使蠕虫状胶束向囊泡转变.

  14. Structure-guided mutational analysis of the OB, HhH, and BRCT domains of Escherichia coli DNA ligase.

    Science.gov (United States)

    Wang, Li Kai; Nair, Pravin A; Shuman, Stewart

    2008-08-22

    NAD(+)-dependent DNA ligases (LigAs) are ubiquitous in bacteria and essential for growth. LigA enzymes have a modular structure in which a central catalytic core composed of nucleotidyltransferase and oligonucleotide-binding (OB) domains is linked via a tetracysteine zinc finger to distal helix-hairpin-helix (HhH) and BRCT (BRCA1-like C-terminal) domains. The OB and HhH domains contribute prominently to the protein clamp formed by LigA around nicked duplex DNA. Here we conducted a structure-function analysis of the OB and HhH domains of Escherichia coli LigA by alanine scanning and conservative substitutions, entailing 43 mutations at 22 amino acids. We thereby identified essential functional groups in the OB domain that engage the DNA phosphodiester backbone flanking the nick (Arg(333)); penetrate the minor grove and distort the nick (Val(383) and Ile(384)); or stabilize the OB fold (Arg(379)). The essential constituents of the HhH domain include: four glycines (Gly(455), Gly(489), Gly(521), Gly(553)), which bind the phosphate backbone across the minor groove at the outer margins of the LigA-DNA interface; Arg(487), which penetrates the minor groove at the outer margin on the 3 (R)-OH side of the nick; and Arg(446), which promotes protein clamp formation via contacts to the nucleotidyltransferase domain. We find that the BRCT domain is required in its entirety for effective nick sealing and AMP-dependent supercoil relaxation.

  15. The MiMeS Survey of Magnetism in Massive Stars

    OpenAIRE

    Wade, G. A.; Grunhut, J. H.; collaboration, the MiMeS

    2012-01-01

    The Magnetism in Massive Stars (MiMeS) survey represents a high precision systematic search for magnetic fields in hot, massive OB stars. To date, MiMeS Large Programs (ESPaDOnS@CFHT, Narval@TBL, HARPSpol@ESO3.6) and associated PI programs (FORS@VLT) have yielded nearly 1200 circular spectropolarimetric observations of over 350 OB stars. Within this sample, 20 stars are detected as magnetic. Follow-up observations of new detections reveals (i) a large diversity of magnetic properties, (ii) ev...

  16. 12 CFR 225.104 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Science.gov (United States)

    2010-01-01

    ... company chooses to have done through another organization. Moreover, the report of the Senate Banking and... Holding Company Act. 225.104 Section 225.104 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF... Holding Company Act. (a) Section 4(c)(1) of the Bank Holding Company Act, among other things, exempts...

  17. Resonant soft x-ray reflectivity of Me/B(4)C multilayers near the boron K edge.

    Science.gov (United States)

    Ksenzov, Dmitriy; Schlemper, Christoph; Pietsch, Ullrich

    2010-09-01

    Energy dependence of the optical constants of boron carbide in the short period Ru/B(4)C and Mo/B(4)C multilayers (MLs) are evaluated from complete reflectivity scans across the boron K edge using the energy-resolved photon-in-photon-out method. Differences between the refractive indices of the B(4)Cmaterial inside and close to the surface are obtained from the peak profile of the first order ML Bragg peak and the reflection profile near the critical angle of total external reflection close to the surface. Where a Mo/B(4)C ML with narrow barrier layers appears as a homogeneous ML at all energies, a Ru/B(4)C ML exhibits another chemical nature of boron at the surface compared to the bulk. From evaluation of the critical angle of total external reflection in the energy range between 184 and 186eV, we found an enriched concentration of metallic boron inside the Ru-rich layer at the surface, which is not visible in other energy ranges.

  18. Complete Genome Sequence of Spiroplasma turonicum Tab4cT, a Bacterium Isolated from Horse Flies (Haematopota sp.)

    Science.gov (United States)

    Lo, Wen-Sui; Gasparich, Gail E.

    2016-01-01

    Spiroplasma turonicum Tab4cT was isolated from a horse fly (Haematopota sp.; probably Haematopota pluvialis) collected at Champchevrier, Indre-et-Loire, Touraine, France, in 1991. Here, we report the complete genome sequence of this bacterium to facilitate the investigation of its biology and the comparative genomics among Spiroplasma spp. PMID:27660788

  19. Ethanol production from D-lactic acid by lactic acid-assimilating Saccharomyces cerevisiae NAM34-4C.

    Science.gov (United States)

    Wakamatsu, Makoto; Tani, Tatsunori; Taguchi, Hisataka; Matsuoka, Masayoshi; Kida, Kenji; Akamatsu, Takashi

    2013-07-01

    The lactic acid-assimilating yeast Saccharomyces cerevisiae NAM34-4C grew rapidly in minimal D-lactate medium (pH 3.5) at 35°C, compared with minimal L-lactate medium. A laboratory strain, S. cerevisiae S288C, did not grow in either medium at pH 3.5. Strain NAM34-4C produced remarkably high levels of ethanol in YPDL medium at pH 3.5, but not at pH 5.5, when D-lactate was provided as the carbon source. Optimal cultivation conditions for ethanol production from D-lactate by strain NAM34-4C were as follows: shaking speed, 60 rpm; initial pH, 3.0; cultivation temperature, 35°C; yeast extract, 5 g/L; peptone, 10 g/L; and D-lactate, 30 g/L. Under these conditions, strain NAM34-4C produced 2.7 g/L ethanol, which is 18% of the theoretical maximal yield (0.51 3 initial D-lactate concentration).

  20. Comparing the Electrochemical Performance of LiFePO4/C Modified by Mg Doping and MgO Coating

    Directory of Open Access Journals (Sweden)

    Jianjun Song

    2013-01-01

    Full Text Available Supervalent cation doping and metal oxide coating are the most efficacious and popular methods to optimize the property of LiFePO4 lithium battery material. Mg-doped and MgO-coated LiFePO4/C were synthesized to analyze their individual influence on the electrochemical performance of active material. The specific capacity and rate capability of LiFePO4/C are improved by both MgO coating and Mg doping, especially the Mg-doped sample—Li0.985Mg0.015FePO4/C, whose discharge capacity is up to 163 mAh g−1, 145.5 mAh g−1, 128.3 mAh g−1, and 103.7 mAh g−1 at 1 C, 2 C, 5 C, and 10 C, respectively. The cyclic life of electrode is obviously increased by MgO surface modification, and the discharge capacity retention rate of sample LiFePO4/C-MgO2.5 is up to 104.2% after 100 cycles. Comparing samples modified by these two methods, Mg doping is more prominent on prompting the capacity and rate capability of LiFePO4, while MgO coating is superior in terms of improving cyclic performance.

  1. Preparation of V-Doped LiFePO4/C as the Optimized Cathode Material for Lithium Ion Batteries.

    Science.gov (United States)

    Sun, Pingping; Zhang, Haiyang; Shen, Kai; Fan, Qi; Xu, Qingyu

    2015-04-01

    LiFe1-x,Vx,PO4/C composites were synthesized by solid state reaction. The effect of carbon coating and V doping on the performance of LiFePO4 has been systematically investigated by X-ray diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), transmission electron microscope (TEM), charge/discharge and cyclic voltammetry (CV) measurement. The results show that carbon coating and proper amount of V incorporation do not significantly change the host crystal structure of LiFePO4, while the electrochemical performance of LiFePO4 can be significantly improved. Particularly, the LiFe0.96V0.04PO4/C exhibits the best performance with a specific discharge capacity of 105.5 mA h/g at 5.0 C, 90.3 mA h/g at 10 C and 66.7 mA h/g at 30 C with stable cycle performance, which is significantly improved compared with the pure LiFePO4/C. The cyclic voltammograms result reveals that V doping could decrease the resistance of LiFePO4/C composite electrode drastically and improve its reversibility. PMID:26353479

  2. Rapid Polyol-Assisted Microwave Synthesis of Nanocrystalline LiFePO4/C Cathode for Lithium-Ion Batteries.

    Science.gov (United States)

    Paul, Baboo Joseph; Gim, Jihyeon; Baek, Sora; Kang, Jungwon; Song, Jinju; Kim, Sungjin; Kim, Jaekook

    2015-08-01

    Nanocrystalline LiFePO4/C has been synthesized under a very short period of time (90 sec) using a polyol-assisted microwave heating synthesis technique. The X-ray diffraction (XRD) data indicates that the rapidly synthesized materials correspond to phase pure olivine. Post-annealing of the as-prepared sample at 600 °C in argon atmosphere yields highly crystalline LiFePO4/C. The morphology of the samples studied using scanning electron microscopy (SEM) reveals the presence of secondary particles formed from aggregation of primary particles in the range of 30-50 nm. Transmission electron microscopy (TEM) images reveal a thin carbon layer coating on the surface of the primary particle. The charge/discharge studies indicate that the as-prepared and annealed LiFePO4/C samples delivered initial discharge capacities of 126 and 160 mA h g-1, respectively, with good capacity retentions at 0.05 mA cm-2 current densities. The post-annealing process indeed improves the crystallinity of the LiFePO4 nanocrystals, which enhances the electrode performance of LiFePO4/C. PMID:26369219

  3. Novel magnetic Fe3O4-C nanoparticles as adsorbents for removal of organic dyes from aqueous solution

    International Nuclear Information System (INIS)

    Highlights: → In this work, novel magnetic Fe3O4-C nanoparticles have been synthesized and employed as high efficient adsorbent for removal cationic dyes from polluted water. → While up to now, little study is done on adsorption of dyes by the Fe3O4-C nanoparticles. → Hence, here we provide a simply and environment friendly method for removal of cationic dyes or other pollutants from water. - Abstract: The magnetic Fe3O4/C core-shell nanoparticles have been synthesized by a simple strategy and used as adsorbents for removal of organic dyes from aqueous solution. The resulting products are characterized by scanning electron microscope (SEM), energy dispersive X-ray spectrometry (EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Raman spectra and Fourier transform infrared spectra (FTIR). Adsorption performances of the nanomaterial adsorbents are tested with removal of methylene blue (MB) and cresol red (CR) from aqueous solution. The effects of solution pH value, adsorption time and capacity of the nanocomposites have been fully investigated. The results reveal that the nanospheres can be easily manipulated by an external magnetic field with high separation efficiency. In addition, the process is clean and safe for purifying water pollution. The prepared Fe3O4/C complex nanomaterials could thus be used as promising adsorbents for the remove organic dyes, especially, cationic dye, from polluted water.

  4. Complete Genome Sequence of Spiroplasma turonicum Tab4cT, a Bacterium Isolated from Horse Flies (Haematopota sp.).

    Science.gov (United States)

    Lo, Wen-Sui; Gasparich, Gail E; Kuo, Chih-Horng

    2016-01-01

    Spiroplasma turonicum Tab4c(T) was isolated from a horse fly (Haematopota sp.; probably Haematopota pluvialis) collected at Champchevrier, Indre-et-Loire, Touraine, France, in 1991. Here, we report the complete genome sequence of this bacterium to facilitate the investigation of its biology and the comparative genomics among Spiroplasma spp. PMID:27660788

  5. A W:B4C multilayer phase retarder for broadband polarization analysis of soft x-ray radiation

    NARCIS (Netherlands)

    MacDonald, Michael A.; Schaefers, Franz; Pohl, R.; Poole, Ian B.; Gaupp, Andreas; Quinn, Frances M.

    2008-01-01

    A W:B4C multilayer phase retarder has been designed and characterized which shows a nearly constant phase retardance between 640 and 850 eV photon energies when operated near the Bragg condition. This freestanding transmission multilayer was used successfully to determine, for the first time, the fu

  6. High reflectance Cr/V multilayer with B(4)C barrier layer for water window wavelength region.

    Science.gov (United States)

    Huang, Qiushi; Fei, Jiani; Liu, Yang; Li, Pin; Wen, Mingwu; Xie, Chun; Jonnard, Philippe; Giglia, Angelo; Zhang, Zhong; Wang, Kun; Wang, Zhanshan

    2016-02-15

    To develop the high reflectance mirror for the short wavelength range of the water window region (λ=2.42-2.73  nm), Cr/V multilayers with B4C barrier layers are studied. The grazing incidence x-ray reflectometry results show that the multilayer interface widths are significantly reduced down to 0.21-0.31 nm, after the introduction of 0.1 nm B4C barrier layers at both interfaces. The [B4C/Cr/B4C/V] multilayer with a large number of bilayers of N=300 maintains the same small interface widths while the surface roughness is only 0.2 nm. According to the transmission electron microscope measurements, the layer structure improvement with barrier layers can be attributed to the suppression of the crystallization of vanadium inside the structure. Using the interface engineered multilayer, a maximum soft x-ray reflectance of 24.3% is achieved at λ=2.441  nm, under the grazing incidence of 42°. PMID:26872167

  7. Enhanced lithium storage in ZnFe2O4-C nanocomposite produced by a low-energy ball milling

    Science.gov (United States)

    Thankachan, Rahul Mundiyaniyil; Rahman, Md Mokhlesur; Sultana, Irin; Glushenkov, Alexey M.; Thomas, Sabu; Kalarikkal, Nandakumar; Chen, Ying

    2015-05-01

    Preparation of novel nanocomposite structure of ZnFe2O4-C is achieved by combining a sol-gel and a low energy ball milling method. The crucial feature of the composite's structure is that sol-gel synthesised ZnFe2O4 nanoparticles are dispersed and attached uniformly along the chains of Super P Li™ carbon black matrix by adopting a low energy ball milling. The composite ZnFe2O4-C electrodes are capable of delivering a very stable reversible capacity of 681 mAh g-1 (96% retention of the calculated theoretical capacity of ∼710 mAh g-1) at 0.1 C after 100 cycles with a remarkable Coulombic efficiency (82%) improvement in the first cycle. The rate capability of the composite is significantly improved and obtained capacity was as high as 702 at 0.1, 648 at 0.5, 582 at 1, 547 at 2 and 469 mAh g-1 at 4 C (2.85 A g-1), respectively. When cell is returned to 0.1 C, the capacity recovery was still ∼98%. Overall, the electrochemical performance (in terms of cycling stability, high rate capability, and capacity retention) is outstanding and much better than those of the related reported works. Therefore, our smart electrode design enables ZnFe2O4-C sample to be a high quality anode material for lithium-ion batteries.

  8. Preparation and electrochemical characterization of PPy-LiFePO{sub 4}/C composites via vapor-phase polymerization

    Energy Technology Data Exchange (ETDEWEB)

    Gong, Q.; Liao, X.Z.; He, Y.; Yang, Y.; Ma, Z.F. [Shanghai Jiao Tong Univ. (China). Dept. of Chemical Engineering

    2010-07-01

    Polypyrrole (PPy) is now being used as a means of improving the electrochemical performance of lithium-iron (LiFePO{sub 4}/C) composite electrode materials for Li-ion batteries. In this study, core-shell LiFePO{sub 4}/C-PPy composites were prepared using a chemical vapor-phase polymerization technique. Transmission electron microscopy (TEM) analyses demonstrated that the LiFePO{sub 4}/C particles were encapsulated with 7.5-nm thick PPy shells. Electrochemical analyses indicated that the high rate capacities and cycle stability of the composite materials was improved when compared with the performance of LiFePO{sub 4}/C composites. Tests on an MCMB/LiFePO{sub 4}-PPy fuel cell showed that the PPy coating reduced Fe dissolution from the LiFePO{sub 4} cathode, and alleviated subsequent Fe deposition on the MCMB anode, thereby enhancing the cell's life cycle. 7 refs., 2 figs.

  9. Low band gap and ionic bonding with charge transfer, threshold in the polymeric lithium fulleride Li(4)C(60)

    NARCIS (Netherlands)

    Macovez, Roberto; Savage, Rebecca; Schiessling, Joachim; Kamaras, Katalin; Rudolf, Petra; Venema, L.C.

    2008-01-01

    We demonstrate the growth of crystalline Li(4)C(60) films. The low-energy electron diffraction pattern of the films indicates the formation of polymer chains in the plane of the surface, consistent with the reported crystal structure. Electron energy loss and photoemission spectra identify the Li(4)

  10. Preparation and characteristics of Li2FeSiO4/C composite for cathode of lithium ion batteries

    Institute of Scientific and Technical Information of China (English)

    GUO Hua-jun; XIANG Kai-xiong; CAO Xuan; LI Xin-hai; WANG Zhi-xing; LI Li-ming

    2009-01-01

    A Li2FeSiO4/C composite cathode for lithium ion batteries was synthesized at 650 ℃ by solid-state reaction. The effects of carbon sources and carbon content on the properties of the Li2FeSiO4/C composites were investigated. The crystalline structure, morphology, carbon content and charge/discharge performance of Li2FeSiO4/C composites were determined by X-ray diffraction(XRD), scanning electron microscopy(SEM), carbon/sulfur analyzer and electrochemical measurements. As carbon content increases in the range of 5%-20%, the amount of Fe3O4 impurity phase decreases. The SEM micrographs show that the addition of the carbon is favorable for reducing the Li2FeSiO4 grain size. Using sucrose as carbon source, the Li2FeSiO4/C composite with 14.5% carbon synthesized at 650 ℃ shows good electrochemical performance with an initial discharge capacity of 144.8 mA-h/g and a capacity retention ratio of 94.27% after 13 cycles.

  11. Neutron irradiation tests on B4C/epoxy composite for neutron shielding application and the parameters assay

    Science.gov (United States)

    Adeli, Ruhollah; Shirmardi, Seyed Pezhman; Ahmadi, Seyed Javad

    2016-10-01

    In this investigation, epoxy resin with a low viscosity amine-based curing agent was chosen as matrix and additives were added to epoxy resin using low speed stirring with ultrasonic waves approach. The chemical stability of resin during fabrication of composites was studied with Fourier transform infrared spectroscopy (FTIR). The effect of B4C particle size (20 and 150 μm) on neutron shielding was investigated. Besides, in order to develop the high performance composites, the effect of ATH (flame retardant) and WO3 powders (for shielding from against gamma rays) on neutron shielding property is considered. The neutron experiments were based on foil activation analysis in thermal column of Tehran Research Reactor (TRR). According to experimental data, required shield thickness (B4C, 150 μm, 3 wt%) for 80% absorption of neutron fluence was calculated about 9.8 mm. Consequently, data show thermal neutron absorption is dependent also on the size of the boron compound filler and show a significant enhancement in shielding performance when using smaller particle size of B4C filler. Furthermore, data obviously show that the neutron attenuation coefficient of reinforced composites increases to 0.345 cm-1 for B4C (20 μm, 5 wt%)/ Epoxy composite shield. As clearly data indicate, adding WO3 and ATH additive had a significant influence on the thermal neutron attenuation property and hybrid shield shows an enhancement of more than 60% in shielding performance.

  12. Constraints on Asian and European sources of methane from CH4-C2H6-CO correlations in Asian outflow

    Science.gov (United States)

    Xiao, Yaping; Jacob, Daniel J.; Wang, James S.; Logan, Jennifer A.; Palmer, Paul I.; Suntharalingam, Parvadha; Yantosca, Robert M.; Sachse, Glen W.; Blake, Donald R.; Streets, David G.

    2004-08-01

    Aircraft observations of Asian outflow from the Transport and Chemical Evolution Over the Pacific (TRACE-P) aircraft mission over the NW Pacific (March and April 2001) show large CH4 enhancements relative to background, as well as strong CH4-C2H6-CO correlations that provide signatures of regional sources. We apply a global chemical transport model simulation of the CH4-C2H6-CO system for the TRACE-P period to interpret these observations in terms of CH4 sources and to explore in particular the unique constraints from the CH4-C2H6-CO correlations. We use as a priori a global CH4 source inventory constrained with National Oceanic and Atmospheric Administration (NOAA) Climate Monitoring and Diagnostics Laboratory (CMDL) surface observations [Wang et al., 2004]. We find that the observed CH4 concentration enhancements and CH4-C2H6-CO correlations in Asian outflow in TRACE-P are determined mainly by anthropogenic emissions from China and Eurasia (defined here as Europe and eastern Russia), with only little contribution from tropical sources (wetlands and biomass burning). The a priori inventory overestimates the observed CH4 enhancements and shows regionally variable biases for the CH4/C2H6 slope. The CH4/CO slopes are simulated without significant bias. Matching both the observed CH4 enhancements and the CH4-C2H6-CO slopes in Asian outflow requires increasing the east Asian anthropogenic source of CH4, and decreasing the Eurasian anthropogenic source, by at least 30% for both. The need to increase the east Asian source is driven by the underestimate of the CH4/C2H6 slope in boundary layer Chinese outflow. The Streets et al. [2003] anthropogenic emission inventory for east Asia fits this constraint by increasing CH4 emissions from that region by 40% relative to the a priori, largely because of higher livestock and landfill source estimates. Eurasian sources (mostly European) then need to be reduced by 30-50% from the a priori value of 68 Tg yr-1. The decrease of

  13. Stability, elastic and magnetostrictive properties of γ-Fe{sub 4}C and its derivatives from first principles theory

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yun; Wang, Zhe [Department of Physics, Xiangtan University, Xiangtan, 411105 Hunan (China); Cao, Juexian, E-mail: jxcao@xtu.edu.cn [Department of Physics, Xiangtan University, Xiangtan, 411105 Hunan (China); Beijing Computational Science Reasearch Center, 100084 Beijing (China)

    2014-11-15

    Using the first-principles full-potential linearized augmented plane-wave method, we investigated the stability, elastic and magnetostrictive properties of γ-Fe{sub 4}C and its derivatives. From the formation energy, we show that the most preferable configuration for MFe{sub 3}C (M=Pd, Pt, Rh, Ir) is that the M atom occupies the corner 1a position rather than 3c position. These derivatives are ductile due to high B/G values except for IrFe{sub 3}C. The calculated tetragonal magnetostrictive coefficient λ{sub 001} value for γ-Fe{sub 4}C is −380 ppm, which is larger than the value of Fe{sub 83}Ga{sub 17} (+207 ppm). Due to the strong SOC coupling strength constant (ξ) of Pt, the calculated λ{sub 001} of PtFe{sub 3}C is −691 ppm, which is increased by 80% compared to that of γ-Fe{sub 4}C. We demonstrate the origin of giant magnetostriction coefficient in terms of electronic structures and their responses to the tetragonal lattice distortion. - Highlights: • The most preferable site for M atom of MFe{sub 3}C (M=Pd, Pt, Rh, Ir) is the corner position. • The magnetostrictive coefficient for γ-Fe{sub 4}C is −380 ppm, larger than the value of Fe{sub 83}Ga{sub 17}. • The calculated λ{sub 001} of PtFe{sub 3}C is −691 ppm, which is increased by 80% compared to that of γ-Fe{sub 4}C.

  14. Study of multi-carbide B4C-SiC/(Al, Si) reaction infiltrated composites by SEM with EBSD

    International Nuclear Information System (INIS)

    In the definition of conceptual developments and design of new materials with singular or unique properties, characterisation takes a key role in clarifying the relationships of composition, properties and processing that define the new material. B4C has a rare combination of properties that makes it suitable for a wide range of applications in engineering: high refractoriness, thermal stability, high hardness and abrasion resistance coupled to low density. However, the low self-diffusion coefficient of B4C limits full densification by sintering. A way to overturn this constraint is by using an alloy, for example Al-Si, forming composites with B4C. Multi-carbide B4C-SiC/(Al, Si) composites were produced by the reactive melt infiltration technique at 1200 – 1350 °C with up to 1 hour of isothermal temperature holds. Pressed preforms made from C-containing B4C were spontaneously infiltrated with Al-Si alloys of composition varying from 25 to 50 wt% Si. The present study involves the characterisation of the microstructure and crystalline phases in the alloys and in the composites by X-ray diffraction and SEM/EDS with EBSD. Electron backscatter diffraction is used in detail to look for segregation and spatial distribution of Si and Al containing phases during solidification of the metallic infiltrate inside the channels of the ceramic matrix when the composite cools down to the eutectic temperature (577 °C). It complements elemental maps of the SEM/EDS. The production of a flat surface by polishing is intrinsically difficult and the problems inherent to the preparation of EBSD qualified finishing in polished samples of such type of composites are further discussed

  15. Regulation of T cell differentiation and alloimmunity by the cyclin-dependent kinase inhibitor p18ink4c.

    Directory of Open Access Journals (Sweden)

    Emily A Rowell

    Full Text Available Cellular proliferation in response to mitogenic stimuli is negatively regulated by the Cip/Kip and the Ink4 families of cyclin-dependent kinase (CDK inhibitors. Several of these proteins are elevated in anergic T cells, suggesting a potential role in the induction or maintenance of tolerance. Our previous studies showed that p27kip1 is required for the induction of T cell anergy and transplantation tolerance by costimulatory blockade, but a role for Ink4 proteins in these processes has not been established. Here we show that CD4+ T cells from mice genetically deficient for p18ink4c divide more rapidly than wild-type cells in response to antigenic, costimulatory and growth factor signals. However, this gain of proliferative function was accompanied by a moderate increase in the rate of cell death, and was accompanied by an overall defect in the generation of alloreactive IFNγ-producing effector cells. Consistent with this, p18ink4c-deficient T cells were unable to induce graft-vs-host disease in vivo, and p18ink4c deficiency cooperated with costimulatory blockade to significantly increase the survival of fully mismatched allografts in a cardiac transplantation model. While both p18ink4c and p27kip1 act to restrict T cell proliferation, p18ink4c exerts an opposite effect from p27kip1 on alloimmunity and organ transplant rejection, most likely by sustaining T cell survival and the development of effector function. Our studies point to additional important links between the cell cycle machinery and the processes of T cell differentiation, survival and tolerance.

  16. Fault Characterization in the Sea of Marmara (Turkey) Using OBS and Land Seismic Stations

    Science.gov (United States)

    Pinar, Ali; Yamamoto, Yojiro; Comoglu, Mustafa; Polat, Remzi; Turhan, Fatih; Takahashi, Narumi; Kalafat, Dogan; Citak, Seckin

    2016-04-01

    The fault segments of the North Anatolian fault (NAF) occurring between Tekirdag basin and Kumburgaz basin are investigated using 15 Ocean Bottom Seismic (OBS) stations. The OBS stations were deployed closely around the fault trace of NAF. During the observation period from September, 2014 until July, 2015 more than one thousand microearthquakes were determined. No uniform seismicity pattern was observed along strike and along dip of the fault segments in an area spanning 100 km from East to West of Marmara Sea. The western fault segments exhibit relatively higher and deeper seismic activity while the eastern segment show shallower and relatively lower seismic activity. Integrating the first motion polarity data from the land based stations of Kandilli Observatory and Earthquake Research Institute (KOERI) with the polarity data acquired from the OBS stations the focal mechanisms of 173 micro-earthquakes were determined. Most of the fault plane solutions indicate predominantly strike-slip mechanism. Several clusters of events are identified along the E-W extending NAF. We derive a focal mechanism for the individual events whenever the number of the polarities are sufficient. In addition, simultaneous inversion of the polarities in a cluster are done to retrieve a stress tensor along with focal mechanisms of the individual events in a cluster. A unique cluster of focal mechanisms was obtained from the events taking place in Western High (WH) region located between Tekirdag Basin (TB) and Central Basin (CB). Several features of this cluster are noticeable; 1) the site is the most seismically active part in Marmara Sea, 2) the site is the locus of the deepest events in the Sea of Marmara, 3) the shallower part of this segment is seismically less active, 4) two subgroups of P-axes of focal mechanisms exist; one oriented NW-SE and other oriented in N-S direction despite the proximity of the location of the events giving clues on the faulting dynamics. The N-S oriented P

  17. Temperature, gravity, and bolometric correction scales for non-supergiant OB stars

    Science.gov (United States)

    Nieva, M.-F.

    2013-02-01

    Context. Precise and accurate determinations of the atmospheric parameters effective temperature and surface gravity are mandatory to derive reliable chemical abundances in OB stars. Furthermore, fundamental parameters like distances, masses, radii, luminosities can also be derived from the temperature and gravity of the stars. Aims: Atmospheric parameters recently determined at high precision with several independent spectroscopic indicators in non-local thermodynamic equilibrium, with typical uncertainties of ~300 K for temperature and of ~0.05 dex for gravity, are employed to calibrate photometric relationships. This is in order to investigate whether a faster tool to estimate atmospheric parameters can be provided. Methods: Temperatures and gravities of 30 calibrators, i.e. well-studied OB main sequence to giant stars in the solar neighbourhood, are compared to reddening-independent quantities of the Johnson and Strömgren photometric systems, assuming normal reddening. In addition, we examine the spectral and luminosity classification of the star sample and compute bolometric corrections. Results: Calibrations of temperatures and gravities are proposed for various photometric indices and spectral types. Once the luminosity of the stars is well known, effective temperatures can be determined at a precision of ~400 K for luminosity classes III/IV and ~800 K for luminosity class V. Furthermore, surface gravities can reach internal uncertainties as low as ~0.08 dex when using our calibration to the Johnson Q-parameter. Similar precision is achieved for gravities derived from the β-index and the precision is lower for both atmospheric parameters when using the Strömgren indices [c1] and [u - b] . In contrast, external uncertainties are larger for the Johnson than for the Strömgren calibrations. Our uncertainties are smaller than typical differences among other methods in the literature, reaching values up to ± 2000 K for temperature and ± 0.25 dex for gravity

  18. Study on the Blistering of B4C/Al Neutron Absorber Plate in the Course of Corrosion%B4C/Al中子吸收板腐蚀过程中的起泡研究

    Institute of Scientific and Technical Information of China (English)

    李刚; 王美玲; 王贯春; 简敏

    2012-01-01

    The corrosion model of cladding blistering on B4C/A1 neutron absorber plate was established by Henry's law, and by means of the model to investigate the relationship between pore radius and temperature factors for blistering. Influence of pore size for the neutron absorber plate blistering was analyzed by using the pore capillary effects. The results show that the hydrogen pressure produced in small radius pores is higher due to Al corrosion, which contributed to B4C/A1 neutron absorber plate cladding blistering. Influence of temperature on the corrosion generated hydrogen pressure is very small, but the main factors affecting the hydrogen pressure is the pore radius sizes. Blistering power of the cladding is hydrogen continuous generation and accumulating in the pore capillary. The water diffuses easily through the pore capillary in B4C/A1 cores, which will cause the cladding blistering because of Al corrosion.%根据亨利定律,建立了B4C/Al中子吸收板包壳腐蚀起泡的模型,计算了孔隙半径、温度对起泡的影响,并利用孔隙毛细管效应分析了孔隙对中子吸收板起泡的影响.结果表明:孔隙半径越小,腐蚀产生的氢气压力越大,B4C/Al中子吸收板包壳更易起泡;温度对腐蚀产生的氢气压力影响非常小,而孔隙半径是影响氢气压力的主要因素;氢气持续产生并在孔隙毛细管中积聚,是包壳产生起泡的动力;水分容易通过孔隙毛细管在B4C/Al芯体中扩散,可导致Al腐蚀,引起包壳起泡.

  19. Effect of microstructure on low temperature electrochemical properties of LiFePO{sub 4}/C cathode material

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Nannan; Zhi, Xiaoke; Wang, Li; Liu, Yanhui; Liang, Guangchuan, E-mail: liangguangchuan@hebut.edu.cn

    2015-10-05

    Graphical abstract: The low temperature performance of Li-ion batteries and LiFePO{sub 4}/C composites was discussed. A conclusion that cathode material is the main limitation for the low temperature performance was come up, by comparing the low temperature performance of 18650 Li-ion batteries with LiMn{sub 2}O{sub 4}, LiNi{sub 1/3}Co{sub 1/3}Mn{sub 1/3}O{sub 2} and LiFePO{sub 4}/C as cathode materials. The low temperature performance results indicate the LiFePO{sub 4}/C microstructure is the main factor influencing the low temperature performance of LiFePO{sub 4}. A new LiFePO{sub 4}/C with pomegranate-like spherical structure was proposed in this paper, which shows superior low temperature performance, which can be attributed to its uniform fine primary particles and smaller primary particles. - Highlights: • Low temperature performance of Li-ion battery and LiFePO{sub 4}/C composite was discussed. • Cathode material mainly decided the low temperature performance of Li-ion battery. • LiFePO{sub 4}/C microstructure mainly affects its low temperature performance. • Pomegranate-like spherical structure LiFePO{sub 4}/C has good low temperature performance. - Abstract: The low-temperature electrochemical performance of Li-ion batteries is mainly determined by the choice of cathode material, as evident from a comparison of the low-temperature electrochemical performance of the 18650 batteries with the LiMn{sub 2}O{sub 4}, LiNi{sub 1/3}Co{sub 1/3}Mn{sub 1/3}O{sub 2}, and LiFePO{sub 4}/C as the cathode, respectively, at −20 °C. LiFePO{sub 4}/C materials with different morphologies and microstructures were prepared by different methods. The samples were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), galvanostatic charge–discharge measurements and EIS. The low-temperature performance of the samples and those of the coin cells utilizing the materials as cathodes were measured. The results

  20. The rotation period distributions of 4--10 Myr T Tauri stars in Orion OB1: New constraints on pre-main-sequence angular momentum evolution

    CERN Document Server

    Karim, Md Tanveer; Briceno, Cesar; Vivas, A Katherina; Raetz, Stefanie; Mateu, Cecilia; Downes, Juan Jose; Calvet, Nuria; Hernandez, Jesus; Neuhauser, Ralph; Mugrauer, Markus; Takahashi, Hidenori; Tachihara, Kengo; Chini, Rolf; Cruz-Dias, Gustavo A; Aarnio, Alicia; James, David J; Hackstein, Moritz

    2016-01-01

    Most existing studies of the angular momentum evolution of young stellar populations have focused on the youngest (1-3 Myr) T Tauri stars. In contrast, the angular momentum distributions of older T Tauri stars (4-10 Myr) have been less studied, even though they hold key insight to understanding stellar angular momentum evolution at a time when protoplanetary disks have largely dissipated and when models therefore predict changes in the rotational evolution that can in principle be tested. We present a study of photometric variability among 1,974 confirmed T Tauri members of various sub-regions of the Orion OB1 association, and with ages spanning 4-10 Myr, using optical time-series from three different surveys. For 564 of the stars (~32% of the weak-lined T Tauri stars and ~13% of the classical T Tauri stars in our sample) we detect statistically significant periodic variations which we attribute to the stellar rotation periods, making this one of the largest samples of T Tauri star rotation periods yet publis...

  1. The Star-formation History and Accretion-Disk Fraction Among the K-Type Members of the Scorpius-Centaurus OB Association

    CERN Document Server

    Pecaut, Mark J

    2016-01-01

    We present results of a spectroscopic survey for new K- and M-type members of Scorpius-Centaurus (Sco-Cen), the nearest OB Association (~100-200 pc). Using an X-ray, proper motion and color-magnitude selected sample, we obtained spectra for 361 stars, for which we report spectral classifications and Li and Halpha equivalent widths. We identified 156 new members of Sco-Cen, and recovered 51 previously published members. We have combined these with previously known members to form a sample of 493 solar-mass (~0.7-1.3 Msun) members of Sco-Cen. We investigated the star-formation history of this sample, and re-assessed the ages of the massive main-sequence turn-off and the G-type members in all three subgroups. We performed a census for circumstellar disks in our sample using WISE infrared data and find a protoplanetary disk fraction for K-type stars of 4.4$^{+1.6}_{-0.9}$% for Upper Centaurus-Lupus and Lower Centaurus-Crux at ~16 Myr and 9.0$^{+4.0}_{-2.2}$% for Upper Scorpius at ~10 Myr. These data are consisten...

  2. Lentivirus-mediated RNA interference targeting the ObR gene in human breast cancer MCF-7 cells in a nude mouse xenograft model

    Institute of Scientific and Technical Information of China (English)

    XUE Rong-quan; GU Jun-chao; DU Song-tao; YU Wei; WANG Yu; ZHANG Zhong-tao; BAI Zhi-gang; MA Xue-mei

    2012-01-01

    Background There is a significant association between obesity and breast cancer,which is possibly due to the expression of leptin.Therefore,it is important to clarify the role of leptin/ObR (leptin receptor) signaling during the progression of human breast cancer.Methods Nude mice with xenografts of MCF-7 human breast cancer cells were administered recombinant human leptin subcutaneous via injection around the tumor site.Mice in the experimental group were intratumorally injected with ObR-RNAi-lentivirus,while negative control group mice were injected with the same dose of negative-lentivirus.Tumor size was blindly measured every other day,and mRNA and protein expression levels of ObR,estrogen receptor α(ERα),and vascular endothelial growth factor (VEGF) for each group were determined.Results Knockdown of ObR-treated xenografted nude mice with a high leptin microenvironment was successfully established.Local injection of ObR-RNAi-lentivirus significantly suppressed the established tumor growth in nude mice.ObR level was significantly lower in the experimental group than in the negative control group,while the amounts of ERα and VEGF expression were significantly lower in the leptin group than in the control group (P <0.01 for all).Conclusions Inhibition of leptin/ObR signaling is essential to breast cancer proliferation and possible crosstalk between ObR and ERα,and VEGF,and may lead to novel therapeutic treatments aiming at targeting ObR in breast cancers.

  3. 4 C Theory and“Hercy Morning News” Distribution Marketing Strategy%4C 理论与《海西晨报》发行营销策略的构建

    Institute of Scientific and Technical Information of China (English)

    张涛

    2015-01-01

    从营销学看4C 营销理论,强调读者的中心地位,符合市场经济条件下报业经济发展的要求,4C营销理论对《海西晨报》社的发行营销策略具有重要启发。可以从生产读者欲求的报纸产品、降低读者满足阅读和购买需求的成本、提高读者阅读和购买报纸的方便程度、与读者加强沟通等四个方面进行设计和构想。%4C marketing theory emphasizes the central position of readers , to meet the requirements of the develop-ment of newspaper industry under the market economy condition .The 4C marketing theory has important inspiration to “Hercy Morning News” agency distribution marketing strategy .Specifically , it is from four aspects as issuing the newspaper for reader's desire , reducing reading cost , improving convenience of purchase , and strengthening com-munication with readers to design the marketing strategy .

  4. Effects of leptin on in vitro maturation, fertilization and embryonic cleavage after ICSI and early developmental expression of leptin (Ob) and leptin receptor (ObR) proteins in the horse

    OpenAIRE

    Arrighi Silvana; Bosi Giampaolo; Cho Yoon S; Ambruosi Barbara; Fiandanese Nadia; Dell'Aquila Maria; Lange Consiglio Anna; Lacalandra Giovanni M; Cremonesi Fausto

    2009-01-01

    Abstract Background The identification of the adipocyte-derived obesity gene product, leptin (Ob), and subsequently its association with reproduction in rodents and humans led to speculations that leptin may be involved in the regulation of oocyte and preimplantation embryo development. In mice and pigs, in vitro leptin addition significantly increased meiotic resumption and promoted preimplantation embryo development in a dose-dependent manner. This study was conducted to determine whether l...

  5. Escape fraction of ionizing photons during reionization: effects due to supernova feedback and runaway OB stars

    CERN Document Server

    Kimm, Taysun

    2014-01-01

    The fraction of hydrogen ionizing photons escaping from galaxies into the intergalactic medium is a critical ingredient in the theory of reionization. We use two zoomed-in, high-resolution (4 pc), cosmological radiation hydrodynamic simulations with adaptive mesh refinement to investigate the impact of two physical mechanisms (supernova feedback and runaway OB stars) on the escape fraction (f_esc) at the epoch of reionization (z>7). We implement a new, physically motivated supernova feedback model that can approximate the Sedov solutions at all (from the free expansion to snowplow) stages. We find that there is a significant time delay of about ten million years between the peak of star formation and that of escape fraction, due to the time required for the build-up and subsequent destruction of the star-forming cloud by supernova feedback. Consequently, the photon number-weighted mean escape fraction for dwarf galaxies in halos of mass 10^8-10^10.5 Msun is found to be ~11%, although instantaneous values of f...

  6. Isolation and purification of Cu-free methanobactin from Methylosinus trichosporium OB3b

    Directory of Open Access Journals (Sweden)

    Kraemer Stephan M

    2011-02-01

    Full Text Available Abstract Background The isolation of highly pure copper-free methanobactin is a prerequisite for the investigation of the biogeochemical functions of this chalkophore molecule produced by methane oxidizing bacteria. Here, we report a purification method for methanobactin from Methylosinus trichosporium OB3b cultures based on reversed-phase HPLC fractionation used in combination with a previously reported resin extraction. HPLC eluent fractions of the resin extracted product were collected and characterized with UV-vis, FT-IR, and C-1s NEXAFS spectroscopy, as well as with elemental analysis and ESI-MS. Results The results showed that numerous compounds other than methanobactin were present in the isolate obtained with resin extraction. Molar C/N ratios, mass spectrometry measurements, and UV-vis spectra indicated that methanobactin was only present in one of the HPLC fractions. On a mass basis, methanobactin carbon contributed only 32% to the total organic carbon isolated with resin extraction. Our spectroscopic results implied that besides methanobactin, the organic compounds in the resin extract comprised breakdown products of methanobactin as well as polysaccharide-like substances. Conclusion Our results demonstrate that a purification step is indispensable in addition to resin extraction in order to obtain pure methanobactin. The proposed HPLC purification procedure is suitable for semi-preparative work and provides copper-free methanobactin.

  7. Fragmentation and OB Star Formation in High-Mass Molecular Hub-Filament System

    CERN Document Server

    Liu, Hauyu Baobab; Ho, Paul T -P; Chen, Huei-Ru; Zhang, Qizhou; Li, Zhi-Yun

    2012-01-01

    Filamentary structures are ubiquitously seen in the interstellar medium. The concentrated molecular mass in the filaments allows fragmentation to occur in a shorter timescale than the timescale of the global collapse. Such hierarchical fragmentation may further assist the dissipation of excessive angular momentum. It is crucial to resolve the morphology and the internal velocity structures of the molecular filaments observationally. We perform 0".5-2".5 angular resolution interferometric observations toward the nearly face-on OB cluster forming region G33.92+0.11. Observations of various spectral lines as well as the millimeter dust continuum emission, consistently trace several $\\sim$1 pc scale, clumpy molecular arms. Some of the molecular arms geometrically merge to an inner 3.0$^{{\\scriptsize{+2.8}}}_{{-\\scriptsize{1.4}}}\\cdot10^{3}$\\,$M_{\\odot}$, 0.6 pc scale central molecular clump, and may directly channel the molecular gas to the warm ($\\sim$50 K) molecular gas immediately surrounding the centrally emb...

  8. The eclipsing, double-lined, Of supergiant binary Cygnus OB2-B17

    Science.gov (United States)

    Stroud, V. E.; Clark, J. S.; Negueruela, I.; Roche, P.; Norton, A. J.; Vilardell, F.

    2010-02-01

    Context. Massive, eclipsing, double-lined, spectroscopic binaries are not common but are necessary to understand the evolution of massive stars as they are the only direct way to determine stellar masses. They are also the progenitors of energetic phenomena such as X-ray binaries and γ-ray bursts. Aims: We present a photometric and spectroscopic analysis of the candidate binary system Cyg OB2-B17 to show that it is indeed a massive evolved binary. Methods: We utilise V band and white-light photometry to obtain a light curve and period of the system, and spectra at different resolutions to calculate preliminary orbital parameters and spectral classes for the components. Results: Our results suggest that B17 is an eclipsing, double-lined, spectroscopic binary with a period of 4.0217±0.0004 days, with two massive evolved components with preliminary classifications of O7 and O9 supergiants. The radial velocity and light curves are consistent with a massive binary containing components with similar luminosities, and in turn with the preliminary spectral types and age of the association.

  9. The eclipsing, double-lined, Of supergiant binary Cyg OB2-B17

    CERN Document Server

    Stroud, V E; Negueruela, I; Roche, P; Norton, A J; Vilardell, F

    2010-01-01

    Massive, eclipsing, double-lined, spectroscopic binaries are not common but are necessary to understand the evolution of massive stars as they are the only direct way to determine stellar masses. They are also the progenitors of energetic phenomena such as X-ray binaries and gamma-ray bursts. We present a photometric and spectroscopic analysis of the candidate binary system Cyg OB2-B17 to show that it is indeed a massive evolved binary. We utilise V band and white-light photometry to obtain a light curve and period of the system, and spectra at different resolutions to calculate preliminary orbital parameters and spectral classes for the components. Our results suggest that B17 is an eclipsing, double-lined, spectroscopic binary with a period of 4.0217+/-0.0004 days, with two massive evolved components with preliminary classifications of O7 and O9 supergiants. The radial velocity and light curves are consistent with a massive binary containing components with similar luminosities, and in turn with the prelimi...

  10. BOREAS TE-1 CO2 and CH4 Flux Data Over the SSA-OBS Site

    Science.gov (United States)

    Anderson, Darwin; Papagno, Andrea; Hall, Forrest G. (Editor); Newcomer, Jeffrey A. (Editor)

    2000-01-01

    The BOREAS TE-1 team collected various data to characterize the soil-plant systems in the BOREAS SSA. Particular emphasis was placed on nutrient biochemistry, the stores and transfers of organic carbon, and how the characteristics were related to measured methane fluxes. The overall transect in the Prince Albert National Park (Saskatchewan, Canada) included the major plant communities and related soils that occurred in that section of the boreal forest. Soil physical, chemical, and biological measurements along the transect were used to characterize the static environment, which allowed them to be related to methane fluxes. Chamber techniques were used to provide a measure of methane production/uptake. Chamber measurements coupled with flask sampling were used to determine the seasonality of methane fluxes. This particular data set contains carbon dioxide and methane flux values from the SSA-OBS site. The data were collected from 09-Jun to 04-Sep-1994. The data are stored in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

  11. HD144548: A young triply eclipsing system in the Upper Scorpius OB association

    CERN Document Server

    Alonso, R; Hoyer, S; Lodieu, N; Palle, E; Sanchis-Ojeda, R

    2015-01-01

    The star HD144548 (=HIP~78977; TYP~6212-1273-1) has been known as a detached eclipsing binary and a bona-fide member of the Upper Scorpius OB association. Continuous photometry from the K2 mission on Campaign Two has revealed the presence of additional eclipses due to the presence of a third star in the system. These are explained by a system composed of the two previously known members of the eclipsing system (Ba and Bb) with a period of 1.63 d, orbiting around an F7-F8V star with a period of 33.945 +/- 0.002 d in an eccentric orbit (e_A = 0.2652 +/- 0.0003). The timing of the eclipses of Ba and Bb reveals the same 33.9 d periodicity, which we interpret as the combination of a light time effect combined with dynamical perturbations on the close system. Here we combine radial velocities and analytical approximations for the timing of the eclipses to derive masses and radii for the three components of the system. We obtain a mass of 1.44 +/- 0.04 M_sun and radius of 2.41 +/- 0.03 R_sun for the A component, and...

  12. Targeting the OB-Folds of Replication Protein A with Small Molecules

    Directory of Open Access Journals (Sweden)

    Victor J. Anciano Granadillo

    2010-01-01

    Full Text Available Replication protein A (RPA is the main eukaryotic single-strand (ss DNA-binding protein involved in DNA replication and repair. We have identified and developed two classes of small molecule inhibitors (SMIs that show in vitro inhibition of the RPA-DNA interaction. We present further characterization of these SMIs with respect to their target binding, mechanism of action, and specificity. Both reversible and irreversible modes of inhibition are observed for the different classes of SMIs with one class found to specifically interact with DNA-binding domains A and B (DBD-A/B of RPA. In comparison with other oligonucleotide/oligosaccharide binding-fold (OB-fold containing ssDNA-binding proteins, one class of SMIs displayed specificity for the RPA protein. Together these data demonstrate that the specific targeting of a protein-DNA interaction can be exploited towards interrogating the cellular activity of RPA as well as increasing the efficacy of DNA-damaging chemotherapeutics used in cancer treatment.

  13. The LMC transition star R84 and the core of the LH 39 OB association

    CERN Document Server

    Heydari-Malayeri, M; Rauw, G; Esslinger, O; Magain, P

    1997-01-01

    On the basis of sub-arcsecond optical imaging we resolve and study the core components of the LMC OB association LH 39. The central star of the association, the rare transition object R84, is also investigated using CASPEC echelle spectroscopy. A new, powerful image restoration code that conserves the fluxes allows us to obtain the magnitudes and colors of the components. We bring out some 30 stars in a ~16"x16", area centered on R84. At a resolution of 0.19", the closest components to R84 are shown to lie at 1.1" NW and 1.7" NW respectively of the transition star. One of these stars is the reddest star of the field after R84 but turns out to be too faint to correspond to the red M2 supergiant previously reported to contaminate the spectrum of R84. If the late-type spectrum is due to a line-of-sight supergiant with a luminosity comparable to R84, it should lie closer than 0.12" to R84. The transition star shows spectral variability between 1982 and 1991. We also note some slight radial velocity variations of ...

  14. Modeling the early evolution of massive OB stars with an experimental wind routine

    CERN Document Server

    Keszthelyi, Zsolt; Wade, Gregg

    2016-01-01

    Stellar evolution models of massive stars are very sensitive to the adopted mass-loss scheme. The magnitude and evolution of mass-loss rates significantly affect the main sequence evolution, and the properties of post-main sequence objects, including their rotational velocities. Driven by potential discrepancies between theoretically predicted and observationally derived mass-loss rates in the OB star range, we particularly aim to investigate the response to mass-loss rates that are lower than currently adopted, in parallel with the mass-loss behavior at the "first" bi-stability jump. We perform 1D hydrodynamical model calculations of single $20 - 60 \\, M_{\\odot}$ Galactic ($Z = 0.014$) stars where the effects of stellar winds are already significant during the main sequence phase. We develop an experimental wind routine to examine the behavior and response of the models under the influence of different mass-loss rates. This observationally guided, simple and flexible wind routine is not a new mass-loss descr...

  15. Inversion of ocean-bottom seismometer (OBS) waveforms for oceanic crust structure: a synthetic study

    Science.gov (United States)

    Li, Xueyan; Wang, Yanbin; Chen, Yongshun John

    2016-08-01

    The waveform inversion method is applied—using synthetic ocean-bottom seismometer (OBS) data—to study oceanic crust structure. A niching genetic algorithm (NGA) is used to implement the inversion for the thickness and P-wave velocity of each layer, and to update the model by minimizing the objective function, which consists of the misfit and cross-correlation of observed and synthetic waveforms. The influence of specific NGA method parameters is discussed, and suitable values are presented. The NGA method works well for various observation systems, such as those with irregular and sparse distribution of receivers as well as single receiver systems. A strategy is proposed to accelerate the convergence rate by a factor of five with no increase in computational complexity; this is achieved using a first inversion with several generations to impose a restriction on the preset range of each parameter and then conducting a second inversion with the new range. Despite the successes of this method, its usage is limited. A shallow water layer is not favored because the direct wave in water will suppress the useful reflection signals from the crust. A more precise calculation of the air-gun source signal should be considered in order to better simulate waveforms generated in realistic situations; further studies are required to investigate this issue.

  16. ALMA Observations of Circumstellar Disks in the Upper Scorpius OB Association

    CERN Document Server

    Barenfeld, Scott A; Ricci, Luca; Isella, Andrea

    2016-01-01

    We present ALMA observations of 106 G-, K-, and M-type stars in the Upper Scorpius OB Association hosting circumstellar disks. With these data, we measure the 0.88 mm continuum and $^{12}$CO $J = 3-2$ line fluxes of disks around low mass ($0.14-1.66$ $M_{\\odot}$) stars at an age of 5-11 Myr. Of the 75 primordial disks in the sample, 53 are detected in the dust continuum and 26 in CO. Of the 31 disks classified as debris/evolved transitional disks, 5 are detected in the continuum and none in CO. The lack of CO emission in approximately half of the disks with detected continuum emission can be explained if CO is optically thick but has a compact emitting area ($\\lesssim 40$ AU), or if the CO is heavily depleted by a factor of at least $\\sim1000$ relative to interstellar medium abundances and is optically thin. The continuum measurements are used to estimate the dust mass of the disks. We find a correlation between disk dust mass and stellar host mass consistent with a power-law relation of $M_{dust}\\propto M_*^...

  17. New Version of SeismicHandler (SHX) based on ObsPy

    Science.gov (United States)

    Stammler, Klaus; Walther, Marcus

    2016-04-01

    The command line version of SeismicHandler (SH), a scientific analysis tool for seismic waveform data developed around 1990, has been redesigned in the recent years, based on a project funded by the Deutsche Forschungsgemeinschaft (DFG). The aim was to address new data access techniques, simplified metadata handling and a modularized software design. As a result the program was rewritten in Python in its main parts, taking advantage of simplicity of this script language and its variety of well developed software libraries, including ObsPy. SHX provides an easy access to waveforms and metadata via arclink and FDSN webservice protocols, also access to event catalogs is implemented. With single commands whole networks or stations within a certain area may be read in, the metadata are retrieved from the servers and stored in a local database. For data processing the large set of SH commands is available, as well as the SH scripting language. Via this SH language scripts or additional Python modules the command set of SHX is easily extendable. The program is open source, tested on Linux operating systems, documentation and download is found at URL "https://www.seismic-handler.org/".

  18. An Updated Look at Binary Characteristics of Massive Stars in the Cygnus OB2 Association

    CERN Document Server

    Kiminki, Daniel C

    2012-01-01

    This work provides a statistical analysis of the massive star binary characteristics in the Cygnus OB2 Association using radial velocity information of 114 B3-O3 primary stars and orbital properties for the 24 known binaries. We compare these data to a series of Monte Carlo simulations to infer the intrinsic binary fraction and distributions of mass ratios, periods, and eccentricities. We model the distribution of mass ratio, log-period, and eccentricity as power-laws and find best fitting indices of alpha=0.1+/-0.5, beta=0.2+/-0.4, and gamma=-0.6+/-0.3 respectively. These distributions indicate a preference for massive companions, short periods, and low eccentricities. Our analysis indicates that the binary fraction of the cluster is 44+/-8% if all binary systems are (artificially) assumed to have P<1000 days; if the power-law period distribution is extrapolated to 10^4 years, a plausible upper limit for bound systems, the binary fraction is ~90+/-10%. Of these binary (or higher order) systems, ~45% will ...

  19. Extended Non-Thermal Emission Possibly Associated with Cyg OB2 #5

    CERN Document Server

    Ortiz-Leon, G N; Tapia, M

    2011-01-01

    Cyg OB2 #5 is a contact binary system (O6.5-7+O5.5-6) with associated radio continuum emission. Two compact ($\\leq 0\\rlap.{"}3$) radio continuum components have been reported previously: the primary one is associated with the contact binary and the secondary one is an arc-like source $\\sim 0\\rlap.{"}8$ to the NE of the primary. This arc-like source results from the interaction of the winds of the contact binary and a B-type star in the region. In this paper we report the detection of an extended ($\\sim 30"$), non-thermal component to the NE of the compact components. We propose that this extended emission could be an unresolved background source (i. e. a radio galaxy), extended galactic emission, or non-thermal emission related with relativistic electrons that are produced in the shock between the contact binary and the B-type star and that are carried away to large distances by the wind from the contact binary.

  20. IRS Spectra of Debris Disks in the Scorpius-Centaurus OB Association

    CERN Document Server

    Jang-Condell, Hannah; Manoj, P; Watson, Dan; Lisse, Carey M; Nesvold, Erika; Kuchner, Marc

    2015-01-01

    We analyze Spitzer/IRS spectra of 110 B-, A-, F-, and G-type stars with optically thin infrared excess in the Scorpius-Centaurus (ScoCen) OB association. The age of these stars ranges from 11-17 Myr. We fit the infrared excesses observed in these sources by Spitzer/IRS and Spitzer/MIPS to simple dust models according to Mie theory. We find that nearly all the objects in our study can be fit by one or two belts of dust. Dust around lower mass stars appears to be closer in than around higher mass stars, particularly for the warm dust component in the two-belt systems, suggesting mass-dependent evolution of debris disks around young stars. For those objects with stellar companions, all dust distances are consistent with trunction of the debris disk by the binary companion. The gaps between several of the two-belt systems can place limits on the planets that might lie between the belts, potentially constraining the mass and locations of planets that may be forming around these stars.

  1. Evidence for Evolution Among Primordial Disks in the 5 Myr Old Upper Scorpius OB Association

    CERN Document Server

    Dahm, S E

    2010-01-01

    Moderate-resolution, near-infrared spectra between 0.8 and 5.2 microns were obtained for 12 late-type (K0-M3) disk-bearing members of the ~5 Myr old Upper Scorpius OB association using SpeX on the NASA Infrared Telescope Facility. For most sources, continuum excess emission first becomes apparent between ~2.2 and 4.5 microns and is consistent with that produced by single-temperature blackbodies having characteristic temperatures ranging from ~500 to 1300 K. The near-infrared spectra for 5 of 12 Upper Scorpius sources exhibit Pa-gamma, Pa-beta and Br-gamma emission, indicators of disk accretion. Using a correlation between Pa-beta and Br-gamma emission line luminosity and accretion luminosity, mass accretion rates (Mdot) are derived for these sources that range from Mdot = 3.5 X 10^{-10} to 1.5 X 10^{-8} MSun per yr. Merging the SpeX observations with Spitzer Space Telescope mid-infrared (5.4-37.0 micron) spectroscopy and 24 and 70 micron broadband photometry, the observed spectral energy distributions are com...

  2. Effects of leptin on in vitro maturation, fertilization and embryonic cleavage after ICSI and early developmental expression of leptin (Ob and leptin receptor (ObR proteins in the horse

    Directory of Open Access Journals (Sweden)

    Arrighi Silvana

    2009-10-01

    Full Text Available Abstract Background The identification of the adipocyte-derived obesity gene product, leptin (Ob, and subsequently its association with reproduction in rodents and humans led to speculations that leptin may be involved in the regulation of oocyte and preimplantation embryo development. In mice and pigs, in vitro leptin addition significantly increased meiotic resumption and promoted preimplantation embryo development in a dose-dependent manner. This study was conducted to determine whether leptin supplementation during in vitro maturation (IVM to horse oocytes could have effects on their developmental capacity after fertilization by IntraCytoplasmic Sperm Injection (ICSI. Methods Compact and expanded-cumulus horse oocytes were matured in medium containing different concentrations (1, 10, 100, 1000 ng/ml of recombinant human leptin and the effects on maturation, fertilization and embryo cleavage were evaluated. Furthermore, early developmental expression of Ob and leptin receptor (Ob-R was investigated by immunocytochemical staining. Results In expanded-cumulus oocytes, the addition of leptin in IVM medium improved maturation (74% vs 44%, for 100 ng/ml leptin-treated and control groups, respectively; P Conclusion Leptin plays a cumulus cell-mediated role in the regulation of oocyte maturation in the mare. Species-specific differences may exist in oocyte sensitivity to leptin.

  3. Fabrication of steel matrix composites locally reinforced with different ratios of TiC/TiB2 particulates using SHS reactions of Ni-Ti-B4C and Ni-Ti-B4C-C systems during casting

    International Nuclear Information System (INIS)

    Steel matrix composites locally reinforced with different molar ratios of in situ TiC/TiB2 particulates (2:1, 1:1 and 1:2, respectively) have been fabricated successfully utilizing the self-propagating high-temperature synthesis (SHS) reactions of Ni-Ti-B4C and Ni-Ti-B4C-C systems during casting. Differential thermal analysis (DTA) and X-ray diffraction (XRD) results reveal that the exothermic reactions of the Ni-Ti-B4C and Ni-Ti-B4C-C systems proceed in such a way that Ni initially reacts with B4C and Ti to form Ni2B and Ti2Ni compounds, respectively, with heat evolution at 1037 deg. C; Subsequently, the external heat and the evolved heat from these exothermic reactions promote the reactions forming TiC and TiB2 at 1133 deg. C. In the composites reinforced with 1:2 molar ratio of TiC/TiB2, almost all TiB2 grains have clubbed structures, while TiC grains exhibit near-spherical morphologies. Furthermore, TiB2 grain sizes decrease, with the increase of TiC content. In particular, in the composites reinforced with 2:1 molar ratio of TiC/TiB2, it is difficult to find the clubbed TiB2 grains. Macro-pores and blowholes are absent in the local reinforcing region of the composites reinforced with 1:1 and 1:2 molar ratios of TiC/TiB2, while a few macro-pores can be observed in the composite reinforced with 2:1 molar ratio of TiC/TiB2. Moreover, the densities of the composites reinforced with 1:1 and 1:2 molar ratios of TiC/TiB2 are higher than that of the composite reinforced with 2:1 molar ratio of TiC/TiB2. The composite reinforced with 1:2 molar ratio of TiC/TiB2 has the highest hardness and the best wear resistance

  4. Lifetime Estimation of the Nanophosphate LiFePO4/C Battery Chemistry Used in Fully Electric Vehicles

    DEFF Research Database (Denmark)

    Swierczynski, Maciej Jozef; Stroe, Daniel Loan; Stroe, Ana-Irina;

    2015-01-01

    There are currently many different lithium ion (Li-ion) chemistries available on the market, and several new players are in the research and development process; however, none of them is superior to the other chemistries in all aspects. Relatively low price, long cycle and calendar lifetime......, and intrinsic safety of the nanophosphate LiFePO4/C Li-ion chemistry make it possible to consider this chemistry for electric vehicle (EV) applications. This paper investigates the lifetime of the nanophosphate LiFePO4/C battery chemistry when it is used for full electrical vehicles. The investigation...... is performed considering a semiempirical calendar and cycle lifetime model, which was developed based on extended accelerated lifetime tests. Both capacity and power capability degradations during calendar and cycle life aging are considered and quantified. Finally, the developed battery cell lifetime model...

  5. Preparation and electrochemical properties of LiFePO4/C composite cathodes for lithium-ion batteries

    Indian Academy of Sciences (India)

    Han Chen; Shao-Chang Han; Wen-Zhi Yu; Hong-Zhi Bo; Chang-Ling Fan; Zhong-Yu Xu

    2006-12-01

    Three kinds of LiFePO4/C composites for lithium-ion batteries were prepared by solid-state reaction. The crystalline structure, morphology and specific surface area of the composites were investigated by X-ray diffraction, scanning electron microscopy and multi-point Brunauer, Emmett and Teller. The results showed that the samples were all well-ordered olivine structures. A network structure, LiFePO4/C composite, was obtained using phenolic resin as carbon source. It possessed the highest specific surface area of 115.65 m2/g, exhibited the highest discharge capacity of 164.89 and 149.12 mAh/g at 0.1 C and 1 C rates, respectively. The discharge capacity was completely recovered when 0.1 C rate was applied again.

  6. Surface Nb-ALLOYING on 0.4C-13Cr Stainless Steel: Microstructure and Tribological Behavior

    Science.gov (United States)

    Yu, Shengwang; You, Kai; Liu, Xiaozhen; Zhang, Yihui; Wang, Zhenxia; Liu, Xiaoping

    2016-02-01

    0.4C-13Cr stainless steel was alloyed with niobium using double glow plasma surface alloying and tribological properties of Nb-alloyed steel such as hardness, friction and wear were measured. Effects of the alloying temperature on microstructure and the tribological behavior of the alloyed steel were investigated compared with untreated steel. Formation mechanisms of Nb-alloyed layers and increased wear resistance were also studied. The result shows that after surface Nb-alloying treatment, the 0.4C-13Cr steel exhibits a diffusion adhesion at the alloyed layer/substrate interface and improved tribological property. The friction coefficient of Nb-alloyed steel is decreased by about 0.3-0.45 and the wear rate after Nb-alloying is only 2-5% of untreated steel.

  7. 10B4C Multi-Grid as an alternative to 3He for Large Area Neutron Detectors

    OpenAIRE

    Correa Magdalena, Jonathan

    2012-01-01

    Despite its present shortage, 3He continues to be the most common neutron converter for detectors in neutron scattering science. However, it is obvious that the development of large area neutron detectors based on alternative neutron converters is rapidly becoming a matter of urgency. In the technique presented, grids each comprising 30 10B4C layers (each 1 µm thick) are used to convert neutrons into ionising particles which are subsequently detected in proportional gas counters. Several pro...

  8. 10B4C Multi-Grid as an alternative to 3He for Large Area Neutron Detectors

    OpenAIRE

    Correa Magdalena, Jonathan; Guerard, Bruno; Campo Ruiz, Jesús Javier

    2013-01-01

    Despite its present shortage, 3He continues to be the most common neutron converter for detectors in neutron scattering science. However, it is obvious that the development of large area neutron detectors based on alternative neutron converters is rapidly becoming a matter of urgency. In the technique presented, grids each comprising 30 10B4C layers (each 1 µm thick) are used to convert neutrons into ionising particles which are subsequently detected in proportional gas counters. Several pro...

  9. High temperature tribological behaviour of carbon based (B{sub 4}C and DLC) coatings in sliding contact with aluminum

    Energy Technology Data Exchange (ETDEWEB)

    Gharam, A. Abou, E-mail: abougha@uwindsor.c [Mechanical Automotive and Materials Engineering Department, University of Windsor, Windsor, ON, N9B3P4 (Canada); Lukitsch, M.J.; Balogh, M.P. [Chemical Sciences and Materials Systems Laboratory, General Motors R and D Center, 30500 Mound Road, Warren, MI 48090-9055 (United States); Alpas, A.T. [Mechanical Automotive and Materials Engineering Department, University of Windsor, Windsor, ON, N9B3P4 (Canada)

    2010-12-30

    Carbon based coatings, particularly diamond-like carbon (DLC) films are known to resist aluminum adhesion and reduce friction at room temperature. This attractive tribological behaviour is useful for applications such as tool coatings used for aluminum forming and machining. However, for those operations that are performed at elevated temperatures (e.g. hot forming) or that generate frictional heat during contact (e.g. dry machining) the suitable coatings are required to maintain their tribological properties at high temperatures. Candidates for these demanding applications include boron carbide (B{sub 4}C) and DLC coatings. An understanding of the mechanisms of friction, wear and adhesion of carbon based coatings against aluminum alloys at high temperatures will help in designing coatings with improved high temperature tribological properties. With this goal in mind, this study focused on B{sub 4}C and a hydrogenated DLC coatings sliding against a 319 grade cast aluminum alloy by performing pin-on-disk experiments at temperatures up to 400 {sup o}C. Experimental results have shown that the 319 Al/B{sub 4}C tribosystem generated coefficient of friction (COF) values ranging between 0.42 and 0.65, in this temperature range. However, increased amounts of aluminum adhesion were detected in the B{sub 4}C wear tracks at elevated temperatures. Focused ion beam (FIB) milled cross sections of the wear tracks revealed that the coating failed due to shearing along the columnar grain boundaries of the coating. The 319 Al/DLC tribosystem maintained a low COF (0.15-0.06) from room temperature up to 200 {sup o}C. This was followed by an abrupt increase to 0.6 at 400 {sup o}C. The deterioration of friction behaviour at T > 200 {sup o}C was attributed to the exhaustion of hydrogen and hydroxyl passivants on the carbon transfer layer formed on the Al pin.

  10. High temperature tribological behaviour of carbon based (B4C and DLC) coatings in sliding contact with aluminum

    International Nuclear Information System (INIS)

    Carbon based coatings, particularly diamond-like carbon (DLC) films are known to resist aluminum adhesion and reduce friction at room temperature. This attractive tribological behaviour is useful for applications such as tool coatings used for aluminum forming and machining. However, for those operations that are performed at elevated temperatures (e.g. hot forming) or that generate frictional heat during contact (e.g. dry machining) the suitable coatings are required to maintain their tribological properties at high temperatures. Candidates for these demanding applications include boron carbide (B4C) and DLC coatings. An understanding of the mechanisms of friction, wear and adhesion of carbon based coatings against aluminum alloys at high temperatures will help in designing coatings with improved high temperature tribological properties. With this goal in mind, this study focused on B4C and a hydrogenated DLC coatings sliding against a 319 grade cast aluminum alloy by performing pin-on-disk experiments at temperatures up to 400 oC. Experimental results have shown that the 319 Al/B4C tribosystem generated coefficient of friction (COF) values ranging between 0.42 and 0.65, in this temperature range. However, increased amounts of aluminum adhesion were detected in the B4C wear tracks at elevated temperatures. Focused ion beam (FIB) milled cross sections of the wear tracks revealed that the coating failed due to shearing along the columnar grain boundaries of the coating. The 319 Al/DLC tribosystem maintained a low COF (0.15-0.06) from room temperature up to 200 oC. This was followed by an abrupt increase to 0.6 at 400 oC. The deterioration of friction behaviour at T > 200 oC was attributed to the exhaustion of hydrogen and hydroxyl passivants on the carbon transfer layer formed on the Al pin.

  11. Characterization of Nanocrystallizatin Surface Layer of 0.4C-1Cr Low Alloy Steel Prepared by Ultrasonic Particulate Peening

    Institute of Scientific and Technical Information of China (English)

    ZHANGJun-bao; LIUYu-liang; ZHAOXin-qi; WUJie; SONGHong-wei; XIONGTian-ying

    2004-01-01

    A nanostructured surface layer was fabricated in a quenched and tempered 0.4C-ICr low alloy steel by ultrasonic particulate peening technique. The microstructure of the nanocrystalline surface layer was characterized by means of TEM and Moessbauer spectroscopy. Experimental results reveal that both cementite and ferrite nanocrystals with an average size of 5 nm were formed in the surface layer of the steel, phase transformation of austenite and dissolution of cementite maybe occur in the process of ultrasonic particulate peening.

  12. Characterization of Nanocrystallizatin Surface Layer of 0.4C-1Cr Low Alloy Steel Prepared by Ultrasonic Particulate Peening

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jun-bao; LIU Yu-liang; ZHAO Xin-qi; WU Jie; SONG Hong-wei; XIONG Tian-ying

    2004-01-01

    A nanostructured surface layer was fabricated in a quenched and tempered 0.4C-1Cr low alloy steel by ultrasonic particulate peening technique. The microstructure of the nanocrystalline surface layer was characterized by means of TEM and Mossbauer spectroscopy. Experimental results reveal that both cementite and ferrite nanocrystals with an average size of 5 nm were formed in the surface layer of the steel, phase transformation of austenite and dissolution of cementite maybe occur in the process of ultrasonic particulate peening.

  13. Formation mechanism of LiFePO 4/C composite powders investigated by X-ray absorption spectroscopy

    Science.gov (United States)

    Hsu, Kuei-Feng; Hu, Shao-Kang; Chen, Chinh-Hsiang; Cheng, Ming-Yao; Tsay, Sun-Yuan; Chou, Tse-Chuan; Sheu, Hwo-Shuenn; Lee, Jyh-Fu; Hwang, Bing-Joe

    The local structure and oxidation states for both the precursors and the LiFePO 4/C composite powders were investigated by X-ray absorption spectroscopy (XAS) to provide a deep insight into their formation mechanism. It was found that the local structure and oxidation states of the precursors and the synthesized LiFePO 4/C powders as well as the electrochemical properties of the synthesized powders were strongly influenced by the R ratio (R: molar ratio of citric acid to total metal ions). The oxidation states of iron ions of the precursors for R = 1 and 0.75 consist mainly of Fe(II) and traces of Fe(III). However, the oxidation state of iron ions of the precursor for R = 0.5 comprises mainly of Fe(III). The oxidation state of iron ions of all the synthesized powders is Fe(II). The structure of the precursors and the synthesized powders for R = 1 and 0.75 is more ordering than that for R = 0.5. It is in good agreement with the observation of the cation mixing obtained from the Riteveld analysis of the XRD data. The better the electrochemical performance is, the more ordering the structure or the less the cation mixing. However, the effect of the R values on the carbon content is also essential for the electrochemical properties of the synthesized LiFePO 4/C composite powders. Increasing the carbon content leads to the increase in the electronic conductivity but impedes the Li + ion diffusion of the composite materials. Consequently, the powders synthesized at the optimal R ratio of 0.75 exhibited the highest initial capacity, about 150 mAh g -1 when cycled at 1/40 C rate at room temperature. The structural scheme of the precursors and the synthesized powders and the formation mechanism of the LiFePO 4/C composite powders are also addressed in this work.

  14. Impact of incorporation of chromium on electrochemical properties of LiFePO4/C for Li-ion batteries

    Directory of Open Access Journals (Sweden)

    Naik Amol

    2015-12-01

    Full Text Available LiFe0.95Cr0.05PO4/C was successfully synthesized by one-step solid-state reaction using a single mode microwave reactor. The effect of incorporation of chromium on LiFePO4 lattice parameters was systematically investigated by X-ray diffraction. Surface analysis was done by scanning electron microscopy and transmission electron microscopy. The ratio of amorphous to graphitic carbon was determined from Raman spectroscopic data. The influence of chromium incorporation on electrochemical properties was studied by recording charge/discharge cycles combined with electrochemical impedance spectroscopy (EIS and cyclic voltammetry. It was found that Cr incorporation significantly enhanced the electrochemical performance of LiFePO4 at all current densities up to 10 C. LiFe0.95Cr0.05PO4/C prepared exhibited the best performance with an initial specific discharge capacity of 157.7, 144.8, 138.3, 131.0, 124.1 and 111.1 mAh·g−1 at 0.1 C, 0.5 C, 1.0 C, 2.0 C, 5 C and 10 C, respectively. The doped sample displayed excellent capacity retention, which was substantially superior than that of pristine LiFePO4/C at a higher current rate.

  15. Enhancement of thermal neutron attenuation of nano-B{sub 4}C, -BN dispersed neutron shielding polymer nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jaewoo, E-mail: kimj@kaeri.re.kr [Nuclear Materials Research Division, Korea Atomic Energy Research Institute, 111-989 Daeduck-daero, Yuseong-gu, Daejeon-si 305-353 (Korea, Republic of); WCI Quantum Beam based Radiation Research Center, Korea Atomic Energy Research Institute, 111-989 Daeduck-daero, Yuseong-gu, Daejeon-si 305-353 (Korea, Republic of); Missouri University Research Reactor, University of Missouri-Columbia, Columbia, MO 65211 (United States); Lee, Byung-Chul [Nuclear Reactor Core Design Division, Korea Atomic Energy Research Institute, 111-989 Daeduck-daero, Yuseong-gu, Daejeon-si 305-353 (Korea, Republic of); Uhm, Young Rang [Radioisotopes Research Division, Korea Atomic Energy Research Institute, 111-989 Daeduck-daero, Yuseong-gu, Daejeon-si 305-353 (Korea, Republic of); Miller, William H. [Missouri University Research Reactor, University of Missouri-Columbia, Columbia, MO 65211 (United States)

    2014-10-15

    Highlights: • Preparation of B{sub 4}C and BN nanopowders using a simple ball milling process. • Homogeneous dispersion and strong adhesion of nano-B{sub 4}C and -BN with polymer matrix. • Enhancement of mechanical properties of the nanocomposites compared to their micro counterparts. • Enhancement of thermal neutron attenuation of the nanocomposites. - Abstract: Nano-sized boron carbide (B{sub 4}C) and boron nitride (BN) powder were prepared using ball milling. Micro- and milled nano-powders were melt blended with high density polyethylene (HDPE) using a polymer mixer followed by hot pressing to fabricate sheet composites. The tensile and flexural strengths of HDPE nanocomposites were ∼20% higher than their micro counterparts, while those for latter decreased compared to neat HDPE. Thermal neutrons attenuation of the prepared HDPE nanocomposites was evaluated using a monochromatic ∼0.025 eV neutron beam. Thermal neutron attenuation of the HDPE nanocomposites was greatly enhanced compared to their micro counterparts at the same B-10 areal densities. Monte Carlo n-Particles (MCNP) simulations based on the lattice structure modeling also shows the similar filler size dependent thermal neutron absorption.

  16. 4C modeling of pulsed-load smoothing in the HELIOS facility using a controlled bypass valve

    Science.gov (United States)

    Zanino, R.; Bonifetto, R.; Hoa, C.; Savoldi Richard, L.

    2013-10-01

    Large variations of the heat load coming from the superconducting magnets to the cryoplant in a tokamak are an undesired consequence of the intrinsically pulsed operation of the machine. In this paper, the cryogenic circuit module of the 4C (Cryogenic Circuit Conductor and Coil) code is used to analyze a subset of the results on pulsed load driven transients experimentally simulated in 2011 in the HELIOS facility (HElium Loop for hIgh lOads Smoothing) at CEA Grenoble, France. We focus on the tests where the smoothing of the pulsed heat load from the supercritical helium loop to the saturated helium bath was achieved by means of a controlled bypass valve. To address this issue, the modeling capability of the cryogenic circuit module of the 4C code is extended to include PI controllers. The computed evolution of temperature, pressure and mass flow rate at different circuit locations shows a good agreement with the measurements, both in the SHe loop and in the LHe bath. These results confirm the accuracy of 4C and contribute a needed step in the process of validation of the code.

  17. Enhanced rate performance of LiFePO4/C by co-doping titanium and vanadium

    Science.gov (United States)

    Long, Yun-Fei; Su, Jing; Cui, Xiao-Ru; Lv, Xiao-Yan; Wen, Yan-Xuan

    2015-10-01

    V and Ti co-doped LiFePO4/C composites were synthesized by a wet milling assisted carbothermal reduction technology. The structure, morphology and electrochemical performance of the samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), magnetic susceptibility, positron annihilation lifetime spectra (PAS), scanning electron microscope (SEM), charge/discharge tests, electrochemical impedance spectroscopy (EIS) and cyclic voltammograms (CV). The results showed that the V and Ti co-doped samples kept the olivine structure of LiFePO4, but the synergistic effects between V3+ and Ti4+ in the lattice can increase the disorder degree of the lattice and create Li+ vacancies in LiFePO4/C, thus improve electronic conductivity and Li+ diffusion coefficient. LiV0.069Ti0.025Fe0.905PO4/C delivers an initial discharge capacity of 144.1 mAh g-1 with a capacity retention ratio of 99.4%, 96.3% and 93.6% after 100, 200 and 300 cycles at 10C, respectively. Remarkably, it still gives a high discharge capacity of 124.8 mAh g-1 even at a high rate of 20C.

  18. High-performance LiFePO4/C electrode with polytetrafluoroethylene as an aqueous-based binder

    Science.gov (United States)

    Gao, Shiyan; Su, Yuefeng; Bao, Liying; Li, Ning; Chen, Lai; Zheng, Yu; Tian, Jun; Li, Jian; Chen, Shi; Wu, Feng

    2015-12-01

    An environmental-friendly and low-cost polymer, polytetrafluoroethylene (PTFE) has been applied as an aqueous-based binder for the fabrication of LiFePO4/C electrode. The electrode with PTFE has been compared to the electrode with the conventional binder, polyvinylidene fluoride (PVDF) via Rheology test, X-ray diffraction (XRD), Fourier Transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and electrochemical tests. The Rheology test indicates that the viscosity of the slurry prepared with PTFE as a binder is better than that prepared with PVDF. The electrochemical measurements demonstrate that the electrode with PTFE binder displays a higher discharge capacity of 161.1 mAh g-1 compared to the electrode with PVDF binder, which shows a discharge capacity of 150.7 mAh g-1. The EIS analysis indicates the LiFePO4/C electrode with PTFE binder shows a higher ionic conductivity and a smaller increasing in charge transfer rate compared to the LiFePO4/C electrode with PVDF binder. In addition, the electrodes applying the aqueous-based binder have been optimized by controlling the moisture content in the electrodes. The electrochemical enhancement of these electrodes can be achieved by controlling the vacuum drying temperature and time during the preparation of the electrodes.

  19. Enhancement of thermal neutron attenuation of nano-B4C, -BN dispersed neutron shielding polymer nanocomposites

    International Nuclear Information System (INIS)

    Highlights: • Preparation of B4C and BN nanopowders using a simple ball milling process. • Homogeneous dispersion and strong adhesion of nano-B4C and -BN with polymer matrix. • Enhancement of mechanical properties of the nanocomposites compared to their micro counterparts. • Enhancement of thermal neutron attenuation of the nanocomposites. - Abstract: Nano-sized boron carbide (B4C) and boron nitride (BN) powder were prepared using ball milling. Micro- and milled nano-powders were melt blended with high density polyethylene (HDPE) using a polymer mixer followed by hot pressing to fabricate sheet composites. The tensile and flexural strengths of HDPE nanocomposites were ∼20% higher than their micro counterparts, while those for latter decreased compared to neat HDPE. Thermal neutrons attenuation of the prepared HDPE nanocomposites was evaluated using a monochromatic ∼0.025 eV neutron beam. Thermal neutron attenuation of the HDPE nanocomposites was greatly enhanced compared to their micro counterparts at the same B-10 areal densities. Monte Carlo n-Particles (MCNP) simulations based on the lattice structure modeling also shows the similar filler size dependent thermal neutron absorption

  20. Cutting tool performance enhancement by using a B{sub 4}C/BCN/C-BN multilayer system

    Energy Technology Data Exchange (ETDEWEB)

    Bejarano Gaitan, G. [Technological Development Center ASTIN-SENA, Cali (Colombia); Group of Corrosion and Protection, University of Antioquia, Medellin (Colombia); Caicedo, J.C. [Technological Development Center ASTIN-SENA, Cali (Colombia); Excellence Center for Novel Materials, Universidad del Valle, Cali (Colombia); Prieto, P. [Excellence Center for Novel Materials, Universidad del Valle, Cali (Colombia); Balogh, Adam G. [Institute of Materials Science, Darmstadt University of Technology (Germany)

    2007-07-01

    Thin films of B{sub 4}C/BCN/c-BN multilayers were deposited on to AISI M2 high speed steel substrates by rf. (13.56 MHz) multi-target magnetron sputtering from high purity (99.99%) h-BN and a (99.5%)B{sub 4}C target, in Ar(90%)/N{sub 2}(10%) gasmixture. For their deposition we varied the bias voltage of the B{sub 4}C films between -50 and -250 V and, for the BCN coatings the nitrogen gas flow from 3% to 12%. A 300-nm thick TiN buffer layer was first deposited to improve the adhesion of all samples. Mechanical properties like hardness, elastic Young modulus, and adhesion were determined by nanoindentation and scratch measurements. Finally, cutting tools were carried out. Tool performance was registered as functions of bilayer numbers showed enhancement between 60% and 107% and a surface roughness reduction of 60% for cutting tools coated with 16 bilayers, compared to uncoated tools. (copyright 2007 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)