WorldWideScience

Sample records for 4-substituted pent-4-enylamines scope

  1. The synthesis of some unsaturated 4-substituted-g-lactones

    Directory of Open Access Journals (Sweden)

    SUREN HUSINEC

    2000-02-01

    Full Text Available The synthesis of conjugated and nonconjugated unsaturated 4-substituted lactones of type 1 and 2 are described. The type 1 lactone was prepared by a two step procedure employing Bredereck's reagent. The type 2 lactone was synthesised by combining the Claisen-Ireland rearrangement and selenolactonisation.

  2. Dihydroxylation of 4-substituted 1,2-dioxines

    DEFF Research Database (Denmark)

    Robinson, Tony V; Pedersen, Daniel Sejer; Taylor, Dennis K;

    2009-01-01

    The synthesis of 2-C-branched erythritol derivatives, including the plant sugar (+/-)-2-C-methylerythritol 2, was achieved through a dihydroxylation/reduction sequence on a series of 4-substituted 1,2-dioxines 3. The asymmetric dihydroxylation of 1,2-dioxines was examined, providing access to...... optically enriched dihydroxy 1,2-dioxanes 4. The synthesized 1,2-dioxanes were converted to other erythro sugar analogues and tetrahydrofurans through controlled cleavage of the endoperoxide linkage....

  3. Antifungal activity of 4-substituted crotonic acid esters.

    Science.gov (United States)

    Gershon, H; Shanks, L; Gawiak, D E

    1976-08-01

    Twenty-three 4-substituted crotonic acid esters were tested for antifungal activity against Candida albicans, Aspergillus niger, Mucor mucedo, and Trichophyton mentagrophytes. For the analogues of the methyl ester containing substituents in the 4 position, the following order of fungitoxicity was observed: I greater than Br greater than Cl greater than CH3S greater than CH3O greater than F=H. Of the homologues of the esters of the 4-iodo and 4-bromo compounds which included methyl, ethyl, n-propyl, n-butyl, n-pentyl, and n-hexyl, ethyl 4-iodocrotonate was most toxic to the four fungi at pH 7.0 in the presence of 10% beef serum (C. albicans, 18mug/ml, A. niger, 40 mug/ml, M. mucedo, 5 mug/ml, T. mentagrophytes, 4 mug/ml). It is believed that the mechanism of fungitoxicity is due, in part, to a nucleophilic reaction involving SH-containing compounds. This is based on the correlation of fungitoxicity with the order of leaving groups in the nucleophilic reaction and the protection against the toxicity of the test compounds to the fungi by cysteine and glutathione.

  4. Synthesis of 4-substituted tetrahydropyridines by cross-coupling of enol phosphates

    DEFF Research Database (Denmark)

    Larsen, U.S.; Martiny, L.; Begtrup, M.

    2005-01-01

    Enol phosphates, synthesized from 4-piperidone, react by palladium catalyzed cross-coupling with arylboronic acids and by iron and palladium catalyzed cross-coupling with Grignard reagents to give 4-substituted tetrahydropyridines. (c) 2005 Elsevier Ltd. All rights reserved.......Enol phosphates, synthesized from 4-piperidone, react by palladium catalyzed cross-coupling with arylboronic acids and by iron and palladium catalyzed cross-coupling with Grignard reagents to give 4-substituted tetrahydropyridines. (c) 2005 Elsevier Ltd. All rights reserved....

  5. Synthesis and cytotoxic activity of 3-phenyl-4-substituted-β-carbolines

    Institute of Scientific and Technical Information of China (English)

    Liu Liu; Ying Ying Xu; Ze Qi Yang; Jian Nan Xiang; Guang Yu Xu

    2012-01-01

    A new class of 3-phenyl-4-substituted-β-carbolines via iodine-mediated electrophilic cyclization as key step were synthesized and their inhibitory activity against three tumor cell lines was evaluated in vitro.It was found that some of the tested compounds showed better cytotoxicity against HeLa and MCF-7 cells than harmine.

  6. Design and synthesis of some novel 4-(4-substituted aryl semicarbazones as anticonvulsant agents

    Directory of Open Access Journals (Sweden)

    Singh Anita

    2010-01-01

    Full Text Available In the present study, a series of 4-(4-substituted aryl semicarbazones were synthesized from substituted anilines and subsequently evaluated for their anticonvulsant activities. The anticonvulsant activities were established by the anticonvulsant drug development (ADD programme NIH, USA using experimental animal, adult male FCM mice (20-25 g and adult Sprague-Dawley rats (100-150 g and screened against electroshock seizure, subcutaneous metrazole and minimal neurotoxicity tests in mice. Compound 7 was found equipotent to carbamazepine in both MES and ScPTZ tests. This study has highlighted the importance of distal alkyl chain which influences the anticonvulsant activity.

  7. Noval 1-substituted-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazole derivatives: Synthesis and pharmacological activity

    Directory of Open Access Journals (Sweden)

    Sabir Hussain

    2015-05-01

    Full Text Available Several-1-carbothioamide-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 2a–d, 1-(pyridine-4-ylcarbonyl-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 3a–d, 1-(5-chloro-6-fluoro-1,3-benzothiazole-2-ylthiocarbamoyl-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 4a–d and 1-[(1,2,4-triazole-4-yl carbothioamide]-3,5-dimethyl-4-[(substituted phenyl diazenyl] pyrazoles 5a–d were synthesized. The structures of the newly synthesized compounds were supported by IR, 1H NMR and mass spectral data. These compounds were investigated for their, anti-inflammatory, analgesic, ulcerogenic, lipid peroxidation, antibacterial and antifungal activities. Some of the synthesized compounds showed potent anti-inflammatory activity along with minimal ulcerogenic effect and lipid peroxidation, compared to ibuprofen and flurbiprofen. Some of the tested compounds also showed moderate antimicrobial activity against tested bacterial and fungal strains.

  8. Microwave-Assisted Synthesis of New N1,N4-Substituted Thiosemicarbazones

    Directory of Open Access Journals (Sweden)

    Aurea Echevarria

    2011-12-01

    Full Text Available We present an efficient procedure for the synthesis of thirty-six N1,N4-substituted thiosemicarbazones, including twenty-five ones that are reported for the first time, using a microwave-assisted methodology for the reaction of thiosemicarbazide intermediates with aldehydes in the presence of glacial acetic acid in ethanol and under solvent free conditions. Overall reaction times (20–40 min when ethanol as solvent, and 3 min under solvent free conditions were much shorter than with the traditional procedure (480 min; satisfactory yields and high-purity compounds were obtained. The thiosemicarbazide intermediates were obtained from alkyl or aryl isothiocyanates and hydrazine hydrate or phenyl hydrazine by stirring at room temperature for 60 min or by microwave irradiation for 30 min, with lower yields for the latter. The preliminary in vitro antifungal activity of thiosemicarbazones was evaluated against Aspergillus parasiticus and Candida albicans.

  9. Recent developments of C-4 substituted coumarin derivatives as anticancer agents.

    Science.gov (United States)

    Dandriyal, Jyoti; Singla, Ramit; Kumar, Manvendra; Jaitak, Vikas

    2016-08-25

    Cancer is a prominent cause of death in global. Currently, the numbers of drugs that are in clinical practice are having a high prevalence of side effect and multidrug resistance. Researchers have made an attempt to expand a suitable anticancer drug that has no MDR and side effect. Coumarin scaffold became an attractive subject due to their broad spectrum of pharmacological activities. Coumarin derivatives extensively explored for anticancer activities as it possesses minimum side effect along with multi-drug reversal activity. Coumarin derivatives can act by various mechanisms on different tumor cell lines depending on substitution pattern of the core structure of coumarin. Substitution on coumarin nucleus leads to the search for more potent compounds. In this review, we have made an effort to give a synthetic strategy for the preparation of C-4 substituted coumarin derivatives as anticancer agents based on their mechanism of action and also discuss the SAR of the most active compound.

  10. Combustion synthesis and characterization of Sn4+ substituted nanocrystalline NiFe2O4

    International Nuclear Information System (INIS)

    A series of Sn4+ substituted NiFe2O4 with general formula Ni1-xSn xFe2O4 (x = 0.0, 0.2, 0.4, 0.6, and 0.8) has been prepared by novel combustion synthetic method. The prepared compounds have been sintered at 1000 deg. C and evaluated for their structural and electrical properties. XRD studies reveal the synthesized compounds are nanocrystalline size with cubic structure. The Fourier transform infrared (FT-IR) spectra show the characteristic features of the synthesized ferrite compounds. The UV-vis spectra reveal the optical band gap of the synthesized compounds. The dc electrical conductivity of the compounds found to increase with increasing measuring temperature. A maximum dc electrical conductivity of 6.0 S cm-1 was obtained at a measuring temperature of 1000 deg. C in the composition of x = 0.8, for which the activation energy for conduction is found to be minimum

  11. Conformational Analysis and Electronic Interactions of Some 4'-Substituted-2-ethylthio-phenylacetates.

    Science.gov (United States)

    Rodrigues, Daniel N S; Ducati, Lucas C; Olivato, Paulo R; Dal Colle, Maurizio

    2015-04-23

    The conformational analysis of various 4'-substituted-2-ethylthio-phenylacetate compounds bearing the substituents NO2 (1), Cl (2), H (3), Me (4), and OMe (5) was performed using infrared (IR) spectroscopic analysis of the carbonyl stretching band (νCO) supported by B3LYP/6-31G(d,p), NBO, QTAIM, and SM5.42R calculations for compounds 1, 3, and 5. The IR spectra in n-hexane indicate the presence of three components, whose intensities decrease upon increasing frequency. In solvents with high permittivity, while the low intensity component at higher frequency disappears, the relative intensity of the component at the intermediate frequency changes with respect to the lower frequency component with differing trends for the various derivatives. It can be observed that the intensity does not vary for compounds 1 and 2, which bear an electron-withdrawing substituent at 4', while it increases in intensity for compounds 3-5. The computational results predict the presence of three gauche conformers, defined by the orientation of the C-S bond with respect to the carbonyl group, whose intensities and νCO frequencies are in agreement with the experimental results. In solvents with increasing permittivity, the SM5.42R solvation model results reproduce the experimental trend observed for the two components in the low frequency region, while it overestimates the amount of the higher frequency conformer. NBO analysis suggests that all the conformers are stabilized to the same extent in the gauche conformation via σC-S → π*CO and πCO → σ*C-S orbital interactions. The different stability can be attributed to the geometrical arrangement of the C(O)-CH2-S-CH2-CH3 moiety, which assumes a six-membered chair-like geometry in the g1 conformer, a six-membered twisted-chair-like geometry in the g2 conformer, and a seven-membered chair-like ring in the g3 conformer. Quantum theory of atoms in molecules (QTAIM) indicates that the ring geometries were formed and stabilized from short

  12. A microwave approach to the synthesis of certain 4-substituted phenyl-6-phenyl-3-cyano-2-pyridones

    Directory of Open Access Journals (Sweden)

    Marinković Aleksandar

    2014-01-01

    Full Text Available A study of the synthesis of 4-substituted phenyl-6-phenyl-3-cyano-2-pyridones from 2-cyano-3-phenylsubstituted acrylates and acetophenone is presented. 2-Pyridones were obtained using conventional as well as microwave synthesis using solvent and solvent free reactions in domestic and lab microwave ovens. The structure of the obtained pyridones was confirmed by m.p., FT-IR, NMR and UV data. [Projekat Ministarstva nauke Republike Srbije, br. 172013

  13. Development of one pot three component synthesis of 1,4-substituted, 1,2,3-triazoles, employing green catalyst

    Directory of Open Access Journals (Sweden)

    Y. L. N arasimha Murthy

    2013-12-01

    Full Text Available An efficient and eco-friendly protocol for the synthesis of 1,4-substituted-1H-1,2,3-triazoles was achieved employing D-glucosamine as a green ligand with CuI as catalyst. An advantage, of high water solubility, of the ligand facilitates easy catalyst removal. All the products were formed in good yields and were characterized by advanced spectral data.

  14. Conformational analysis of some N,N-diethyl-2-[(4'-substituted) phenylthio] acetamides.

    Science.gov (United States)

    Vinhato, Elisângela; Olivato, Paulo R; Zukerman-Schpector, Julio; Dal Colle, Maurizio

    2013-11-01

    The conformational analysis of some N,N-diethyl-2[(4'-substituted)phenylthio]acetamides bearing the substituents OMe 1, Me 2, H 3, Cl 4, Br 5 and NO26, was performed by νCO IR analysis, along with B3LYP/6-311++G(d,p) and Polarisable Continuum Model (PCM) calculations, as well as NBO analysis for 1, 3, and 6 and X-ray diffraction for 4. The results of the calculations indicated the existence of two stable conformation pairs, i.e. gauche (anti; syn) (most stable) and cis (anti; syn) in the gas phase. The gauche conformers were less polar with respect to the cis ones for 1 and 3, but more polar for 6. The most intense IR carbonyl doublet component observed at the lower frequency can be ascribed to the gauche conformers g(anti; syn) for 3-6 in n-C6H14, which is in agreement with the gauche and cis relative stabilities and frequencies resulting from the PCM calculations. Similarly, the single IR band for 1 and 2 in n-hexane may be attributed to the gauche conformers. The PCM calculations compared well with the IR data for the compounds in solution, showing that there is a progressive increase of the cis/gauche population ratio as the solvent polarity increases. The NBO analysis indicated that the gauche(anti; syn) conformation in the gas phase was stabilized by the relevant LPS4→πC2O1(∗),πC2O1→σC3S4(∗),σC3S4→πC2O1(∗),πC2O1(∗)→σC3S4(∗), and LPO1→σ(∗)C11H28 orbital interactions, which were absent in the cis(anti; syn) conformer. On the contrary, the cis conformer for derivatives 1, 3, and 6 were stabilized by the σC3-S4(∗)→σ(∗)C2N5 orbital interaction (through bond coupling), along with the additional LPO1→σ(∗)S4C10 interaction for 6. Moreover, the electrostatic repulsion between the C(δ+)S(δ-) and C(δ+)O(δ-) dipoles (Repulsive Field Effect) contributed to both the larger destabilization and increase of the νCO frequency of the cis conformer with respect to the gauche conformer. X-ray single crystal analysis indicates that

  15. A tandem Mannich addition–palladium catalyzed ring-closing route toward 4-substituted-3(2H-furanones

    Directory of Open Access Journals (Sweden)

    Jubi John

    2014-06-01

    Full Text Available A facile route towards highly functionalized 3(2H-furanones via a sequential Mannich addition–palladium catalyzed ring closing has been elaborated. The reaction of 4-chloroacetoacetate esters with imines derived from aliphatic and aromatic aldehydes under palladium catalysis afforded 4-substituted furanones in good to excellent yields. 4-Hydrazino-3(2H-furanones could also be synthesized from diazo esters in excellent yields by utilising the developed strategy. We could also efficiently transform the substituted furanones to aza-prostaglandin analogues.

  16. Planar geometry of 4-substituted-2,2'-bipyridines synthesized by Sonogashira and Suzuki cross-coupling reactions

    Energy Technology Data Exchange (ETDEWEB)

    Luong Thi, T. T., E-mail: thuyltt@hnue.edu.vn; Nguyen Bich, N.; Nguyen, H. [Hanoi National University of Education, Chemistry Department (Viet Nam); Van Meervelt, L., E-mail: luc.vanmeervelt@chem.kuleuven.be [KU Leuven, Chemistry Department (Belgium)

    2015-12-15

    Two 4-substituted 2,2'-bipyridines, namely 4-(ferrocenylethynyl)-2,2'-bipyridine (I) and 4-ferrocenyl-2,2'-bipyridine (II) have been synthesized and fully characterized via single-crystal X-ray diffraction and {sup 1}H and {sup 13}C NMR analyses. The π-conjugated system designed from 2,2'-bipyridine modified with the ferrocenylethynyl and ferrocenyl groups shows the desired planarity. In the crystal packing of I and II, the molecules arrange themselves in head-to-tail and head-to-head motifs, respectively, resulting in consecutive layers of ferrocene and pyridine moieties.

  17. ESI-MS spectra of 3-cyano-4-(substituted phenyl-6-phenyl-2(1H-pyridinones

    Directory of Open Access Journals (Sweden)

    BRATISLAV Ž. JOVANOVIĆ

    2009-03-01

    Full Text Available Twelve 3-cyano-4-(substituted phenyl-6-phenyl-2(1H-pyridinones were investigated by tandem mass spectrometry using positive as well as negative electrospray ionization. The influence of the electron affinity of the substituent and the steric effect on the fragmentation is discussed. Pyridinones with a substituent of low proton affinity show loss of water, HCN or benzene from the pyridinone ring in the first step of MS2 fragmentations. Oppositely, if a substituent with high proton affinity is present on the phenyl ring in the 4-position of pyridinone, the fragmentation paths are complex, depending mainly on the substituent proton acceptor ability. Elimination of neutral molecules CO, HCN, H2O, PhH (benzene or Ph and CN radicals are fragmentation processes common for all compounds in the subsequent steps of the fragmentations.

  18. Synthesis, characterization and biological activity of new cyclization products of 3-(4-substituted benzylidene)-2-pyrido[1,2-]pyrimidine 2,4-(3)-diones

    Indian Academy of Sciences (India)

    Abha Bishnoi; Suruchi Singh; Anil K Tiwari; Krishna Srivastava; Ram Raghuvir; Chandrakant M Tripathi

    2013-03-01

    A method is presented for the synthesis of 4-(substituted phenyl)-3-(3-substituted phenyl)4-spiro[isoxazole-5,3'-pyrido[1,2-]pyrimidine]-2',4'-dione (3), 3-(4-substituted phenyl)-3-isoxazole[3, 4-]pyrido[1,2-]pyrimidin-4-(3a)-one (4) and 3-(4-substituted phenyl) 3,3a-dihydropyrazolo[3,4-]pyrido[1,2-]pyrimidin-4-(2)-one (5) which consists of the conversion of 2-pyrido[1,2-]pyrimidine-2,4(3)-dione (1) to chalcones (2) and their 1,3-dipolar cycloaddition with appropriate aldoximes to give spiro compounds and heterocyclization using amines to yield isoxazolines and pyrazolines. All the compounds were screened for their antimicrobial and antitubercular activity.

  19. Novel high-affinity and selective biaromatic 4-substituted ¿-hydroxybutyric acid (GHB) analogues as GHB ligands

    DEFF Research Database (Denmark)

    Høg, Signe; Wellendorph, Petrine; Nielsen, Birgitte;

    2008-01-01

    Gamma-hydroxybutyrate (GHB) is a metabolite of gamma-aminobutyric acid (GABA) and has been proposed to function as a neurotransmitter or neuromodulator. GHB is used in the treatment of narcolepsy and is a drug of abuse. GHB binds to both GABA(B) receptors and specific high-affinity GHB sites...... in brain, of which the latter have not been linked unequivocally to function, but are speculated to be GHB receptors. In this study, a series of biaromatic 4-substituted GHB analogues, including 4'-phenethylphenyl, 4'-styrylphenyl, and 4'-benzyloxyphenyl GHB analogues, were synthesized and characterized...... pharmacologically in a [3H](E,RS)-(6,7,8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylidene)acetic acid ([3H]NCS-382) binding assay and in GABA(A) and GABA(B) receptor binding assays. The compounds were selective for the high-affinity GHB binding sites and several displayed Ki values below 100 nM. The affinity...

  20. Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3

    DEFF Research Database (Denmark)

    Alaux, Sebastien; Kusk, Mie; Sagot, Emanuelle;

    2005-01-01

    A series of nine L-2,4-syn-4-alkylglutamic acid analogues (1a-i) were synthesized in high yield and high enantiomeric excess (>99% ee) from their corresponding 4-substituted ketoglutaric acids (2a-i), using the enzyme aspartate aminotransferase (AAT) from pig heart or E. coli. The synthesized...

  1. Synthesis and anticancer activities of 4-(4-substituted piperazin)-5,6,7-trialkoxy quinazoline derivatives.

    Science.gov (United States)

    Zhang, Ying; Huang, Yin-Jiu; Xiang, Hong-Mei; Wang, Pei-Yi; Hu, De-Yu; Xue, Wei; Song, Bao-An; Yang, Song

    2014-05-01

    A series of 4-(4-substituted piperazin)-5,6,7-trialkoxy quinazoline was prepared by conventional heating methods. Among these compounds, the crystal structure of compound 10o (CCDC: 916922) was determined by X-ray crystallography. Bioassay results showed that most target compounds had certain inhibition activities against proliferation of tumor cells, and some compounds even had good broad-spectrum inhibition activities. The ethoxyl series of compounds possessed higher inhibition activities against tumor cells than the methoxyl series of compounds. Bioactivity tests showed that the IC50 values of compound 10s against PC3, MGC803, A375, and A549 cells were 1.8, 2.8, 1.3, and 2.9 μΜ, respectively, which were much higher than those of commercial gefitinib (7.2, 7.6, 7.2, and 9.8 μM, respectively). Conversely, the IC50 values of compound 10s were very low against NH3T3, indicating only weak effect on normal cells as also proven by lactate dehydrogenase and acridine orange/ethidium bromide staining. Analyses of cell configuration and cell cycle revealed that compound 10s possibly caused cells to remain at G0/G1 phase by inhibiting cell proliferation for 24 h. Compound 10s also inhibited the phosphorylation of ERK1/2 and P38 with obvious concentration dependence. Thus, these compounds can inhibit the proliferation of A549 cells through the interruption of ERK1/2 and P38signaling pathways.

  2. Novel 4-substituted phenyl-2,2'-bichalcophenes and aza-analogs as antibacterial agents: a structural activity relationship

    Directory of Open Access Journals (Sweden)

    Hussin WA

    2013-03-01

    Full Text Available Warda A Hussin,1 Mohamed A Ismail,2,3 Wael M El-Sayed2,41Al-Azhr University, Faculty of Science, Department of Botany and Microbiology, Cairo; 2King Faisal University, Faculty of Science, Departments of Biological Sciences and Chemistry, Al-Hufof, Ahsaa, KSA; 3Mansoura University, Faculty of Science, Department of Chemistry, Mansoura; 4University of Ain Shams, Faculty of Science, Department of Zoology, Abbassia, Cairo, EgyptAbstract: Antibiotic resistance is a major health problem; therefore, new antibacterial agents will need to be continuously developed. A series of novel bichalcophenes has been tested and found to have antimicrobial activity against selected bacteria. Due to the promising antimicrobial effects of these 4-substituted phenyl bichalcophene derivatives, the study reported here was launched to examine the interaction between novel bichalcophenes and tetracycline. The minimum inhibitory concentration values for all bichalcophenes were between 8 and 64 µM. Many of the bichalcophenes had synergistic activity that increased the inhibitory effect of tetracycline against bacterial growth, as indicated by the fractional inhibitory concentration index. The post-antibiotic effects of the novel bichalcophenes were determined. Many bichalcophenes were able to elongate the period required for bacteria to recover and grow after a brief exposure to tetracycline. Escherichia coli did not develop resistance to many bichalcophenes over a period of 7 days. A structural activity relationship could be characterized, as monocationic derivatives were more active than the corresponding mononitriles. The presence of a pyridyl group and/or furan ring reduced the activity, while the presence of a phenyl or thiophene ring enhanced the antibacterial activity. Our results suggest that bichalcophenes could be useful to elevate the shelf life of many antibiotics.Keywords: synergic interaction, fractional inhibitory concentration, post-antibiotic effect

  3. Synthesis and anticancer activities of 4-(4-substituted piperazin)-5,6,7-trialkoxy quinazoline derivatives.

    Science.gov (United States)

    Zhang, Ying; Huang, Yin-Jiu; Xiang, Hong-Mei; Wang, Pei-Yi; Hu, De-Yu; Xue, Wei; Song, Bao-An; Yang, Song

    2014-05-01

    A series of 4-(4-substituted piperazin)-5,6,7-trialkoxy quinazoline was prepared by conventional heating methods. Among these compounds, the crystal structure of compound 10o (CCDC: 916922) was determined by X-ray crystallography. Bioassay results showed that most target compounds had certain inhibition activities against proliferation of tumor cells, and some compounds even had good broad-spectrum inhibition activities. The ethoxyl series of compounds possessed higher inhibition activities against tumor cells than the methoxyl series of compounds. Bioactivity tests showed that the IC50 values of compound 10s against PC3, MGC803, A375, and A549 cells were 1.8, 2.8, 1.3, and 2.9 μΜ, respectively, which were much higher than those of commercial gefitinib (7.2, 7.6, 7.2, and 9.8 μM, respectively). Conversely, the IC50 values of compound 10s were very low against NH3T3, indicating only weak effect on normal cells as also proven by lactate dehydrogenase and acridine orange/ethidium bromide staining. Analyses of cell configuration and cell cycle revealed that compound 10s possibly caused cells to remain at G0/G1 phase by inhibiting cell proliferation for 24 h. Compound 10s also inhibited the phosphorylation of ERK1/2 and P38 with obvious concentration dependence. Thus, these compounds can inhibit the proliferation of A549 cells through the interruption of ERK1/2 and P38signaling pathways. PMID:24675177

  4. Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands.

    Science.gov (United States)

    Yates, S L; Phillips, J G; Gregory, R; Pawlowski, G P; Fadnis, L; Khan, M A; Ali, S M; Tedford, C E

    1999-05-01

    A new series of 1H-4-substituted imidazole compounds were synthesized and identified as potent and selective histamine (HA) H3 receptor ligands. These ligands establish that HA H3 antagonists exhibit stereoselective and conformational preferences in their binding to the HA H3 receptor. Structure-activity relationships were determined in vitro by HA H3 receptor-binding affinities using [3H]Nalpha-methylhistamine and rat cerebral cortical tissue homogenates. Several derivatives containing olefin, amide, and acetylene functional groups were identified as potent HA H3 receptor ligands. In the olefin series, GT-2227 (4-(6-cyclohexylhex-cis-3-enyl)imidazole) was identified as a potent HA H3 receptor ligand with a Ki of 4.2 +/- 0.6 nM, while the trans isomer (GT-2228) displayed a reduced potency (Ki = 15.2 +/- 2.4 nM). GT-2227 was also found to have excellent central nervous system penetration in an ex vivo binding paradigm (ED50 = 0.7 mg/kg i.p.). In the acetylene series, GT-2260 and GT-2286 both exhibited high affinity (Ki = 2.9 +/- 0.2 and 0.95 +/- 0.3 nM) and excellent central nervous system penetration profiles (ED50 = 0.43 and 0.48 mg/kg i.p., respectively). As a prototype for the series, GT-2227 showed high affinity for the human HA H3 receptor (3.2 nM) and minimal affinity for the human HA H1 (Ki = 13,407 +/- 540 nM) and H2 (Ki = 4,469 +/- 564 nM) receptor subtypes. GT-2227 also showed good selectivity for the HA H3 receptor over a broad spectrum of other neurotransmitter receptors (IC50 >/= 1 microM). Furthermore, GT-2227 improved acquisition in a cognitive paradigm without behavioral excitation or effect on spontaneous locomotor activity. In summary, the present studies demonstrate the development of novel HA H3-selective ligands, and lend support for the use of such agents in the treatment of disorders associated with cognitive or attentional deficits.

  5. An Efficient Synthesis of Highly Optically Active 4-Substituted-2(5H)-furanones from Chiral 3-Bromo-2(5H)-furanone

    Institute of Scientific and Technical Information of China (English)

    FAN, Xue-E(范雪娥); HUANG, Min(黄敏); HUANG, Hui(黄慧); CHEN, Qing-Hua(陈庆华)

    2004-01-01

    Highly optically active 4-substituted-2(5H)-furanones 6a-6j were obtained in good yields with de≥98% by the tandem Michael addition/elimination reaction of chiral 3-bromo-2(5H)-furanone (4a), which was conveniently prepared starting from 2-furaldehyde under mild conditions. The products were identified on the basis of their satisfactory elemental analysis and spectroscopic data of IR, UV, 1H NMR, 13C NMR and mass spectra. The stereochemistry and absolute configuration of this type of compounds were established by the X-ray crystallographic study. The reaction provided a short and efficient synthesis of the interesting highly optically active 4-substituted-2(5H)-furanones containing an active pyrimidine and a purine base group.

  6. Market scope

    International Nuclear Information System (INIS)

    Nova Scotia's Energy Strategy is aimed at opening the electricity market to wholesale competition, allowing eligible wholesale customers (such as municipal distribution utilities) to buy their electricity from competitive sources. The Nova Scotia Electricity Marketplace Governance Committee (EMGC) is concerned that this will not promote long-term competition because these eligible customers form only a very small fraction (1.6 per cent) of the total electricity demand in the province. This report examines the possible extensions of competition beyond the minimum specified in the Energy Strategy. It also identifies approaches that the EMGC may consider, including other potential levels of competition and their associated issues. The report discussed the issue of implementing wholesale competition as it relates to unbundling of the transmission tariff from the cost of energy supply and from the cost of distribution in retail marketing. The stages of expanding the market scope were also described with reference to large industrial customers, medium industrial and large commercial customers, and small commercial and residential customers. The report states that it is unlikely that the transition to an open access transmission market will need to be reversed, as it is likely to be an essential component of any further development. The EMGC feels it could minimize future transition costs and promote future evolution of competition by recommending for an institutional and market structure that is compatible with a broader competitive market

  7. Scope ambiguities and conditionals

    NARCIS (Netherlands)

    Over, David; Douven, Igor; Verbrugge, Sara

    2013-01-01

    Scope ambiguities in natural language have been much discussed by linguists and philosophers. There has been some psychological work on the scope ambiguities of negation, but we present the first experiments on modal scope ambiguities in conditionals, with special attention paid to the scope ambigui

  8. Synthesis of 4-substituted oxazolo[4,5-c]quinolines by direct reaction at the C-4 position of oxazoles.

    Science.gov (United States)

    Akula, Mahesh; Thigulla, Yadagiri; Davis, Connor; Jha, Mukund; Bhattacharya, Anupam

    2015-03-01

    A facile synthesis of 4-aryl substituted oxazolo[4,5-c]quinolines has been described via a modified Pictet-Spengler method and using Cu(TFA)2 as a catalyst. The developed methodology directly functionalizes the C-4 position of oxazoles without the aid of any prefunctionalization, in the presence of the more reactive C-2 position in good yields. The versatility of the established method has been demonstrated by its application in the synthesis of 4-substituted oxazolo-[1,8]naphthyridine ring systems. PMID:25574832

  9. N-(4-Substituted-benzoyl)-N'-(beta-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods

    OpenAIRE

    Veronika Nagy; Nora Felfoeldi; Balint Konya; Praly, Jean-Pierre; Tibor Docsa; Pal Gergely; Chrysina, Evangelia D.; Tiraidis, Costas; Kosmopoulou, Magda N.; Alexacou, Kyra-Melinda; Konstantakaki, Maria; Leonidas, Demetres D.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Kozmon, Stanislav

    2012-01-01

    N-(4-Substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas (substituents: Me, Ph, Cl, OH, OMe, NO2, NH2, COOH, and COOMe) were synthesised by ZnCl2 catalysed acylation of O-peracetylated beta-D-glucopyranosyl urea as well as in reactions of O-peracetylated or O-unprotected glucopyranosylamines and acyl-isocyanates. O-deprotections were carried out by base or acid catalysed transesterifications where necessary. Kinetic studies revealed that most of these compounds were low micromolar inhibitors...

  10. Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation

    Science.gov (United States)

    Nguyen Van, Tai; Hospital, Audrey; Lionne, Corinne; Jordheim, Lars P; Dumontet, Charles; Périgaud, Christian; Chaloin, Laurent

    2016-01-01

    Summary A series of seventeen β-hydroxyphosphonate ribonucleoside analogues containing 4-substituted-1,2,3-triazoles was synthesized and fully characterized. Such compounds were designed as potential inhibitors of the cytosolic 5’-nucleotidase II (cN-II), an enzyme involved in the regulation of purine nucleotide pools. NMR and molecular modelling studies showed that a few derivatives adopted similar structural features to IMP or GMP. Five derivatives were identified as modest inhibitors with 53 to 64% of cN-II inhibition at 1 mM. PMID:27559400

  11. Regioselective synthesis and anti-HIV activity of the novel 2- and 4- substituted pyrazolo [4,5-e] [ 1,2,4]thiadiazines

    Institute of Scientific and Technical Information of China (English)

    Xin Yong Liu; Ren Zhang Yan; Nian Gen Chen; Wen Fang Xu

    2007-01-01

    The new regioisomer 7-methyl-pyrazolo[4,5-e] [1,2,4]thiadiazine nucleus (5) was synthesized, and its novel mono-N2- or N4-substituted pyrazolo[4,5-e][1,2,4]thiadiazines (6, 7) were regioselectively prepared by deprotonation of N2 or/and N4 atoms with different molar ratio of NaH and alkyl halides. Anti-HIV-1 screening tests showed some compounds to be potent as HIV-1 nonnucleoside reverse transcriptase inhibitors (HIV-1 NNRTIs).(C) 2006 Xin Yong Liu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  12. Synthesis and antitumor evaluation of some new N4 substituted sulfa pyridine derivatives with studying the synergistic effect of γ-irradiation

    International Nuclear Information System (INIS)

    The aim of the present investigation is to synthesize a new class of N4 substituted sulfa pyridine derivatives with anticipated cytotoxic activity. All the newly synthesized compounds were screened for their in-vitro cytotoxic activity against breast cancer cell line (MCF-7) compared to the reference drug Doxorubicin. Also the synergism of the most potent synthesized compounds with γ- radiation was studied. Moreover, a molecular docking study was carried out by docking the most active synthesized compounds in the active site of Cyclin Dependent Kinase 2 receptor to assess their inhibitory effect upon this enzyme as this may have a role in their anticancer activity.

  13. Antimicrobial screening and one-pot synthesis of 4-(substituted-anilinomethyl-3-(2-naphthyl-1-phenyl-1H-pyrazole derivatives

    Directory of Open Access Journals (Sweden)

    Neelima Goel

    2014-01-01

    Full Text Available Aim: Synthesis of series of 4-(substituted-anilinomethyl-3-(2-naphthyl-1-phenyl-1H-pyrazole derivatives (4a-4k and their in vitro antifungal and antibacterial screening. Materials and Methods: A series of compounds (4a-4k was synthesized through direct reductive amination of 3-(naphthalen-2-yl-1-phenyl-1H-pyrazole-4-carbaldehyde with various substituted aromatic amines using NaBH 4 in the presence of I 2 as reducing agent. The reaction was carried out in anhydrous methanol under neutral conditions at room temperature. The structures of synthesized compounds (4a-4k were established on the basis of IR, 1 H and 13 C-NMR, and mass spectral data. Results: All 4-(substituted-anilinomethyl-3-(2-naphthyl-1-phenyl-1H-pyrazole derivatives (4a-4k were tested in vitro for antifungal and antibacterial activities against different fungal and bacterial strains. Most of the compounds exhibited considerable antifungal activity, but poor antibacterial activity against the test strains. Conclusion: In the series compound 4e, 4g, 4j, and 4k, showed excellent antifungal activity against the fungal strain Aspergillus niger (MTCC 281 and Aspergillus flavus MTCC 277 (% inhibition in the range of 47.7-58.9.

  14. Synthesis of N1-3-{(4-Substituted aryl-3-chloro-2-oxo- azetidine)-iminocarbamyl}-propyl-6-nitroindazole Derivatives and Their Biological Significance%Synthesis of N1-3-{(4-Substituted aryl-3-chloro-2-oxo- azetidine)-iminocarbamyl}-propyl-6-nitroindazole Derivatives and Their Biological Significance

    Institute of Scientific and Technical Information of China (English)

    Samadhiya, Pushkal; Sharma, Ritu; Srivastava, Santosh K.; Srivastava, Savitri D.

    2011-01-01

    Synthesis of N1-3-{(4-substitute daryl-3-chloro-2-oxo-azetidine)-iminocarbamyl}-propyl-6-nitroindazole 4a-- 4s was conducted by a conventional method. All the compounds were synthesized and characterized by IR, 1H NMR, 13C NMR, FAB-Mass techniques and chemical methods. All the final synthesized compounds were evaluated for their antimicrobial activity and antitubercular activity with MIC values against some selected microorganisms.

  15. Mass Spectrometric Fragmentation of 1,8-Bis[4-substituted-(oxazolin-2-yl)] anthracenes: Ring-contraction Rearrangement of Oxazoline Ring under Electron-Impact Ionization Conditions

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The mass spectrometric fragmentation of 1,8-bis[4-substituted(oxazolin-2-yl)] anthracenes(AnBOXes) was investigated by using mass-analyzed ion kinetic energy spectrometry under electron-impact ionization conditions. All the compounds could undergo a ring contraction by the loss of an RCH=CH2 molecule to form 1-oxazirinyl-8-(oxazolin-2-yl) anthracene ions, which could further lose an R radical, followed by the loss of oxazoline. These ions could also eliminate an R radical and subsequently undergo ring-contraction rearrangements to lose a CHCH2O fragment and an epoxide molecule, respectively. The ions that are formed could further lose CHCH2O and CH2=CH fragments. Several ring-contraction rearrangements of the oxazoline ring were observed under electron-impact ionization conditions.

  16. Design, synthesis and nonlinear optical properties of (E)-1-(4-substituted)-3-(4-hydroxy-3-nitrophenyl) prop-2-en-1-one compounds

    Science.gov (United States)

    Saha, Amrita; Shukla, Vijay; Choudhury, Sudip; Jayabalan, J.

    2016-06-01

    A new series of (E)-1-(4-substituted)-3-(4-hydroxy-3-nitrophenyl) prop-2-en-1-one compounds have been synthesized by Claisen-Schmidt condensation reaction. Nonlinear optical characterization were carried out using z-scan technique with nanosecond pulses. These samples are found to exhibit strong nonlinear absorption at 532 nm and the nonlinear absorption coefficient of these samples exponentially increases with the increase of phonon characteristic energy. This relation speaks the role of phonon in the origin of nonlinear absorption in these compounds. The reported dependence of optical nonlinearity of the chalcone derivatives on the phonon characteristic energy will help in designing similar class of new molecules with high nonlinear coefficients.

  17. Spectroscopic and X-ray crystallographic evidence for electrostatic effects in 4-substituted cyclohexanone-derived hydrazones, imines, and corresponding salts.

    Science.gov (United States)

    Dibble, David J; Ziller, Joseph W; Woerpel, K A

    2011-10-01

    The axial conformer of several 4-substituted cyclohexanone hydrazone salts was found to predominate in solution. Changes in the charge of the molecule and the polarity of the solvent led to changes in the conformational preference of each molecule that were consistent with electrostatic stabilization of the axial conformer. (1)H NMR spectroscopic analysis was utilized to determine the structure of cyclohexanone-derived substrates by comparison to conformationally restricted trans-decalone derivatives and computational models. X-ray crystallography demonstrated that the axial configuration of a pendant benzyloxy group is the preferred conformation of an iminium ion in the solid state. The structure of a neutral hydrazone was also determined to favor the axial configuration for a pendant benzyloxy group in the solid state.

  18. Synthesis, properties and colour assessment of some new 5-(3- and 4-substituted phenylazo-4,6-dimethyl-3-cyano-2-pyridones

    Directory of Open Access Journals (Sweden)

    DUSAN MIJIN

    2006-05-01

    Full Text Available A series of 5-(3- and 4-substituted phenylazo-4,6-dimethyl-3-cyano-2-pyridones were synthesized, starting from acetylacetone and arenediazonium salt, followed by condensation with cyanoacetamide using a modified literature procedure. The experimental investigation included modification of the synthetic procedure in terms of solvent, temperature, isolation techniques as well as purification and identification of the products. The azo dyes were characterized by melting point, IR, UV/Vis, 1H NMR and MS data. HPLC analyses were also performed. The 2-hydroxypyridine/ 2-pyridone tautomeric equilibration was found to depend on the polarity of the applied solvents. A colour assessment of the solid dyes and dyed polyester fabrics was also performed and the correlation between the colour and the structure of the dyes is discussed.

  19. Spectroscopy and quantum-chemical calculations of nitro-bis-bipyridyl complexes of ruthenium(II) with 4-substituted pyridine ligands

    Science.gov (United States)

    Reshetova, K. I.; Krauklis, I. V.; Litke, S. V.; Ershov, A. Yu.; Chizhov, Yu. V.

    2016-04-01

    The luminescence, absorption, and luminescence excitation spectra of complexes cis-[Ru(bpy)2(L)(NO2)]+ [bpy = 2,2'-bipyridyl, L = pyridine, 4-aminopyridine, 4-dimethylaminopyridine, 4-picoline, isonicotinamide, or 4,4'-bipyridyl] in alcoholic (4 : 1 EtOH-MeOH) solutions are studied at 77 K. A linear correlation is established between the energy of the lowest electronically excited metal-toligand charge transfer state d π(Ru) → π*(bpy) of the complexes and the pKa parameter of the free 4-substituted pyridines used as ligands L. The B3LYP/[6-31G(d)+LanL2DZ(Ru)] hybrid density functional method is used to optimize the geometry of complexes and calculate their electronic structure and the charge distribution on the atoms of the nearest environment of ruthenium(II) ions. It is shown that there exists a mutually unambiguous correspondence between the charge on the nitrogen atom of ligands L coordinated in the complex and the pK a parameter of ligands. The calculated energies of the electronically excited metal-to-ligand charge transfer states of complexes linearly (correlation coefficient 0.99) depend on the charge on the nitrogen atom of ligands L, which completely agrees with the experimental data.

  20. N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.

    Science.gov (United States)

    Nagy, Veronika; Felföldi, Nóra; Kónya, Bálint; Praly, Jean-Pierre; Docsa, Tibor; Gergely, Pál; Chrysina, Evangelia D; Tiraidis, Costas; Kosmopoulou, Magda N; Alexacou, Kyra-Melinda; Konstantakaki, Maria; Leonidas, Demetres D; Zographos, Spyros E; Oikonomakos, Nikos G; Kozmon, Stanislav; Tvaroška, Igor; Somsák, László

    2012-03-01

    N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl) ureas (substituents: Me, Ph, Cl, OH, OMe, NO(2), NH(2), COOH, and COOMe) were synthesised by ZnCl(2) catalysed acylation of O-peracetylated β-d-glucopyranosyl urea as well as in reactions of O-peracetylated or O-unprotected glucopyranosylamines and acyl-isocyanates. O-deprotections were carried out by base or acid catalysed transesterifications where necessary. Kinetic studies revealed that most of these compounds were low micromolar inhibitors of rabbit muscle glycogen phosphorylase b (RMGPb). The best inhibitor was the 4-methylbenzoyl compound (K(i)=2.3μM). Crystallographic analyses of complexes of several of the compounds with RMGPb showed that the analogues exploited, together with water molecules, the available space at the β-pocket subsite and induced a more extended shift of the 280s loop compared to RMGPb in complex with the unsubstituted benzoyl urea. The results suggest the key role of the water molecules in ligand binding and structure-based ligand design. Molecular docking study of selected inhibitors was done to show the ability of the binding affinity prediction. The binding affinity of the highest scored docked poses was calculated and correlated with experimentally measured K(i) values. Results show that correlation is high with the R-squared (R(2)) coefficient over 0.9. PMID:22325154

  1. Synthesis and antimosquito properties of 2,6-substituted benzo[d]thiazole and 2,4-substituted benzo[d]thiazole analogues against Anopheles arabiensis.

    Science.gov (United States)

    Venugopala, Katharigatta Narayanaswamy; Krishnappa, Manjula; Nayak, Susanta K; Subrahmanya, Bhat K; Vaderapura, Jayashankaragowda P; Chalannavar, Raju K; Gleiser, Raquel M; Odhav, Bharti

    2013-07-01

    A novel and efficient one pot synthesis was developed for 2,6-substituted-benzo[d]thiazole analogues 4a-k and 2,4-substituted-benzo[d]thiazole analogues 4l-pvia three component condensation reaction of substituted arylaldehyde, 2-amino-6-halo/4-methyl-benzo[d]thiazole and 2-naphthol or 6-hydroxyquinoline in presence of 10% w/v NaCl in water by microwave method. This method enabled for short reaction times, easy work-up and significant high yields. The title compound 4b was used for single crystal X-ray studies in order to understand its conformation and packing features. The title compounds 4a-p were screened for antimosquito properties such as repellency, insecticidal and larvicidal activity against Anopheles arabiensis by mosquito feeding-probing assay, cone bio-assay and standard WHO larvicidal assay, respectively. Among these analogous 4b, 4d and 4p exhibit the highest repellent activity comparable to the positive control DEET, and 4a and 4k knockdown most mosquitoes on repellent assays.

  2. Novel high-affinity and selective biaromatic 4-substituted gamma-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies.

    Science.gov (United States)

    Høg, Signe; Wellendorph, Petrine; Nielsen, Birgitte; Frydenvang, Karla; Dahl, Ivar F; Bräuner-Osborne, Hans; Brehm, Lotte; Frølund, Bente; Clausen, Rasmus P

    2008-12-25

    Gamma-hydroxybutyrate (GHB) is a metabolite of gamma-aminobutyric acid (GABA) and has been proposed to function as a neurotransmitter or neuromodulator. GHB is used in the treatment of narcolepsy and is a drug of abuse. GHB binds to both GABA(B) receptors and specific high-affinity GHB sites in brain, of which the latter have not been linked unequivocally to function, but are speculated to be GHB receptors. In this study, a series of biaromatic 4-substituted GHB analogues, including 4'-phenethylphenyl, 4'-styrylphenyl, and 4'-benzyloxyphenyl GHB analogues, were synthesized and characterized pharmacologically in a [3H](E,RS)-(6,7,8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylidene)acetic acid ([3H]NCS-382) binding assay and in GABA(A) and GABA(B) receptor binding assays. The compounds were selective for the high-affinity GHB binding sites and several displayed Ki values below 100 nM. The affinity of the 4-[4'-(2-iodobenzyloxy)phenyl] GHB analogue 17b was shown to reside predominantly with the R-enantiomer (Ki = 22 nM), which has higher affinity than previously reported GHB ligands.

  3. Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.

    Science.gov (United States)

    Abdel-Aziz, Alaa A-M; El-Azab, Adel S; Alanazi, Amer M; Asiri, Yousif A; Al-Suwaidan, Ibrahim A; Maarouf, Azza R; Ayyad, Rezk R; Shawer, Taghreed Z

    2016-10-01

    The potential antitumor activities of a series of 7-(4-substituted piperazin-1-yl)fluoroquinolone derivatives (1-14a,b) using ciprofloxacin and norfloxacin as scaffolds are described. These compounds exhibit potent and broad spectrum antitumor activities using 60 human cell lines in addition to the inherent antibacterial activity. Compounds 1a, 2a, 3b, 6b and 7a were found to be the most potent, while 2b, 5b, and 6a were found to have an average activity. The results of this study demonstrated that compounds 1a, 2a, 3b, 6b and 7a (mean GI50; 2.63-3.09 µM) are nearly 7-fold more potent compared with the positive control 5-fluorouracil (mean GI50; 22.60 µM). More interestingly, compounds 1a, 2a, 3b, 6b and 7a have an almost antitumor activity similar to gefitinib (mean GI50; 3.24 µM) and are nearly 2-fold more potent compared to erlotinib (mean GI50; 7.29 µM). In silico study and ADME-Tox prediction methodology were used to study the antitumor activity of the most active compounds and to identify the structural features required for antitumor activity. PMID:26226179

  4. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.

    Science.gov (United States)

    Cao, Dong; Liu, Yibin; Yan, Wei; Wang, Chunyu; Bai, Peng; Wang, Taijin; Tang, Minghai; Wang, Xiaoyan; Yang, Zhuang; Ma, Buyun; Ma, Liang; Lei, Lei; Wang, Fang; Xu, Bixue; Zhou, Yuanyuan; Yang, Tao; Chen, Lijuan

    2016-06-23

    In this paper, a series of novel 4-substituted coumarin derivatives were synthesized. Among these compounds 34, 39, 40, 43, 62, 65, and 67 exhibited significant antiproliferative activity toward a panel of tumor cell lines at subnanomolar IC50 values. Compound 65 showed potent antiproliferative ability (IC50 values of 7-47 nM) and retained full activity in multidrug resistant cancer cells. Compound 65 caused G2/M phase arrest and interacted with the colchicine-binding site in tubulin, as confirmed by immune-fluorescence staining, microtubule dynamics assays, and competition assays with N,N'-ethylene-bis(iodoacetamide). Compound 65 reduced the cell migration and disrupted capillary-like tube formation in HUVEC cells. Importantly, compound 65 significantly and dose-dependently reduced tumor growth in four xenografts models including paclitaxel sensitive and resistant ovarian tumors (A2780s and A2780/T), adrmicycin sensitive and resistant breast tumors (MCF-7 and MCF-7/ADR), suggesting that compound 65 is a promising novel antimitotic compound for the potential treatment of cancer. PMID:27213819

  5. Scope Processing in Chinese

    Science.gov (United States)

    Zhou, Peng; Gao, Liqun

    2009-01-01

    The standard view maintains that quantifier scope interpretation results from an interaction between different modules: the syntax, the semantics as well as the pragmatics. Thus, by examining the mechanism of quantifier scope interpretation, we will certainly gain some insight into how these different modules interact with one another. To observe…

  6. Design, synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl) [6H-indolo (2,3-b)quinoxalin-6-yl]methyl-amino)benzoate derivatives

    Institute of Scientific and Technical Information of China (English)

    Yellajyosula Lakshmi Narasimha Murthy; Nagalakshmi Karthikeyan; Govindh Boddeti; Bhagavathula S. Diwakar; E. Rajendra Singh

    2011-01-01

    A series of new methyl-4-((substituted phenyl) [6H-indolo (2,3-b)quinoxalin-6yllmethylamino)benzoate derivatives have been synthesized and assayed for their antibacterial activity on 9 different bacterial strains. Among the screened compounds 2e-2g exhibited potent inhibitory activity compared to standard drug employed, worth further investigation.

  7. 1, 3-Dipolar cycloaddition reactions: Synthesis of 5-benzyl-1-(2',4'-dibromophenyl)-3-(4"-substituted phenyl)-3a,4,6,6a-tetrahydro-1, 5-pyrrolo[3,4-]pyrazole-4,6-dione derivatives

    Indian Academy of Sciences (India)

    Manpreet Kaur; Baldev Singh; Baljit Singh

    2013-11-01

    1,3-Dipolar cycloaddition of nitrilimines 3 with -benzyl maleimide 4 has provided 5-benzyl-1-(2',4'-dibromophenyl)-3-(4"-substituted phenyl)-3a,4,6,6a-tetrahydro-1,5-pyrrolo[3,4-]pyrazole-4,6-dione derivatives 5 in excellent yield as the only isomer through a concerted pathway.

  8. Spectrophotometric, voltammetric and cytotoxicity studies of 2-hydroxy-5-methoxyacetophenone thiosemicarbazone and its N(4)-substituted derivatives: A combined experimental-computational study

    Science.gov (United States)

    Akgemci, Emine Guler; Saf, Ahmet Ozgur; Tasdemir, Halil Ugur; Türkkan, Ercan; Bingol, Haluk; Turan, Suna Ozbas; Akkiprik, Mustafa

    2015-02-01

    In this study, 2-hydroxy-5-methoxyacetophenone thiosemicarbazone (HMAT) and its novel N(4) substituted derivatives were synthesized and characterized by different techniques. The optical band gap of the compounds and the energy of HOMO were experimentally examined by UV-vis spectra and cyclic voltammetry measurements, respectively. Furthermore, the conformational spaces of the compounds were scanned with molecular mechanics method. The geometry optimization, HOMO and LUMO energies, the energy gap of the HOMO-LUMO, dipole moment of the compounds were theoretically calculated by the density functional theory B3LYP/6-311++G(d,p) level. The minimal electronic excitation energy and maximum wavelength calculations of the compounds were also performed by TD-DFT//B3LYP/6-311++G(d,p) level of theory. Theoretically calculated values were compared with the related experimental values. The combined results exhibit that all compounds have good electron-donor properties which affect anti-proliferative activity. The cytotoxic effects of the compounds were also evaluated against HeLa (cervical carcinoma), MCF-7 (breast carcinoma) and PC-3 (prostatic carcinoma) cell lines using the standard MTT assay. All tested compounds showed antiproliferative effect having IC50 values in different range. In comparison with that of HMAT, it was obtained that while ethyl group on 4(N)-substituted position decreased in potent anti-proliferative effect, the phenyl group on the position increased in anti-proliferative effect for the tested cancer cell line. Considering the molecular energy parameters, the cytotoxicity activities of the compounds were discussed.

  9. RADAR PPI Scope Overlay

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — RADAR PPI Scope Overlays are used to position a RADAR image over a station at the correct resolution. The archive maintains several different RADAR resolution...

  10. Scope and Sequence.

    Science.gov (United States)

    Callison, Daniel

    2002-01-01

    Discusses scope and sequence plans for curriculum coordination in elementary and secondary education related to school libraries. Highlights include library skills; levels of learning objectives; technology skills; media literacy skills; and information inquiry skills across disciplines by grade level. (LRW)

  11. Synthesis of 7-Methoxy-4'-substituted Flavones%7-甲氧基-4'-取代黄酮类化合物的合成

    Institute of Scientific and Technical Information of China (English)

    安景云; 刘湘; 杨青青; 陆小倩

    2012-01-01

    In this paper,an expedient procedure to synthesize 7-methoxy-4'-substituted flavones from 2-hydroxy-4-methoxyacetophenone and 4-substitutedbenzoyl chlorides was discovered and optimized. The four flavones were obtained via the successive reactions of esterification, rearrangement and cyclization. The esterification was carried out for 0. 5 ~ 4 h at room temperature, with the mole ratio of 1: (1. 0 ~ 1. 3 ) [ n ( 2-hydroxy-4-methoxyacetophenone) : n (4-substitutedbenzoyl chlorides ) ] ; the rearrangement was performed for 2 ~6 h at 30 ~ 60 ℃ ;the cyclization took place for 2 ~5 h at 80 ~ 100 ℃ ,with the catalyst of acetic acid/sulfuric acid ( V( acetic acid) : V( sulfuric acid )=(15~20):l]. Under the optimum reaction conditions, the target products were obtained with overall yields of 50% ~ 75% and with a purity of more than 95%. The structures of the compounds were confirmed by 'HNMR,IR and MS.%以2-羟基-4-甲氧基苯乙酮和4种对位取代的苯甲酰氯为原料,经过酯化、重排、成环3步反应方便地合成了4种7-甲氧基-4’-取代黄酮类化合物,并对各步反应条件进行了优化,得到的优化条件为:酯化反应∶常温反应0.5~4 h,n(2-羟基-4-甲氧基苯乙酮)∶n(对位取代苯甲酰氯)=1∶(1.0~1.3);重排反应:反应温度30 ~ 60℃,反应时间2~6 h;成环反应:反应温度80~100℃,反应时间2~5h,催化剂CH3COOH/H2SO4两者体积比(15~20)∶1.目标产物总收率50%~75%,HPLC分析纯度达95%以上.化合物结构经1HNMR、IR和MS证实.

  12. Interconversion study in 1,4-substituted six-membered cyclohexane-type rings. Structure and dynamics of trans-1,4-dibromo-1,4-dicyanocyclohexane.

    Science.gov (United States)

    Bain, Alex D; Baron, Maximo; Burger, Steven K; Kowalewski, Valdemar J; Rodríguez, Marina Belén

    2011-08-25

    Cyclohexane is an extremely flexible molecule that oscillates, at room temperature, between two clearly distinct and extreme conformations that cannot be distinguished at room temperature; so much so that the NMR spectrum is a single line that includes all 12 protons be they axial or equatorial. This raises the interesting question as to what happens when there are equal substituents at the 1 and 4 carbon atoms of the ring. Therefore substitution in the 1,4-positions in the cyclohexane ring has been the subject of considerable interest because some form of interconversion between extreme conformations could lead to the existence of a rather unusual behavior. To study this problem, the interconversion in (di- or tetra-1,4)-substituted six-membered cyclohexane-type rings, trans-1,4-dibromo-1,4-dicyanocyclohexane, was found to be a particularly suitable candidate. Although X-ray diffraction studies on the crystalline solid found the molecule to be centrosymmetric, it still shows a significant dipole moment μ in solution, as determined with a procedure that leads to the vapor phase values of μ. Furthermore, the low magnetic field proton NMR spectrum at ambient temperature appears as a single line, a situation that changes with increasing field intensity and different solvents. Both these effects are attributed to dynamics, because small distortions can easily disrupt the exact cancellation of the individual dipoles (which are quite strong) associated with each end of the molecule. The molecule can exist in two forms, with both the bromines in an axial geometry or both in an equatorial position. Interconversion between these forms is observed, as in the parent cyclohexane. The single NMR line observed at low magnetic fields is due to fast exchange and requires that the two forms have roughly equal populations. Spectra obtained at low temperature confirm this, and variable-temperature studies allow measurement of the rates, leading to an enthalpy of activation of 62 k

  13. SYNTHESIS OF SOME NEW 1-SUBSTITUTED 3-TRIFLUROMETHYL-5-PHENYL-4- (SUBSTITUTED PHENYL AZO PYRAZOLES AS ANTIFUNGAL AGENTS Synthese einiger NEW 1-substituierten 3-Trifluormethyl-5-phenyl-4- (Substituiertes Phenyl AZO PYRAZOLE als Antipilzmittel

    Directory of Open Access Journals (Sweden)

    Vineeta Sareen, Vineeta Khatri and Prakash Jain

    2011-08-01

    Full Text Available Some new fluorine containing azo pyrazoles have been synthesized by the condensation of hydrazono derivatives (obtained by the reaction of 1, 3-diketone with diazonium salts in the presence of sodium acetate, with substituted hydrazines to give 1-substituted-3-trifluoromethyl- 5-phenyl-4-(substituted phenyl azo pyrazoles. The structure of these compounds are confirmed on the basis of elemental analysis and spectral studies.

  14. Cosmetology: Scope and Sequence.

    Science.gov (United States)

    Nashville - Davidson County Metropolitan Public Schools, TN.

    This scope and sequence guide, developed for a cosmetology vocational education program, represents an initial step in the development of a systemwide articulated curriculum sequence for all vocational programs within the Metropolitan Nashville Public School System. It was developed as a result of needs expressed by teachers, parents, and the…

  15. Frozen Scope and Grammatical Optimization

    Science.gov (United States)

    Freedman, Michael

    2014-01-01

    The literature on quantifier scope has repeatedly observed that some otherwise expected permutations of scope taking elements are unavailable. Various methods have been proffered explaining these facts. This thesis aims to unify three disparate areas where the scope of operators seems to be frozen: the interaction of universal quantifiers with…

  16. Synthesis and antifungal activity of 1- ( 1 H-1, 2,4-triazol-1-yl) -2- (2,4-difluorophenyl)-3-(4-substituted acyl piperazin-1-yl)-2-propanols

    Institute of Scientific and Technical Information of China (English)

    LIANG Shuang; LIU Chao-mei; ZHU Jie; HE Qiu-qin; JIANG Yuan-ying; CAO Yong-bin

    2004-01-01

    Objective: To study the effect of fluconzole derivatives from a side chain containing 4-substituted acyl piperazin-1-yl on antifungal activity. Methods: Fourteen title compounds were synthesized and confirmed by the elementary analysis, 1HNMR and IR spectra. Five deep fungal strains and 3 shallow fungal strains were chosen as the experimental strains. Minimum inhibitory concentrations(MICs) of all title compounds were determined by the method recommended by the National Committee for Clinical Laboratory Standards (NCCLS) using RPMI 1640 test medium. Results: Among the 14title compounds, 12 were first reported. The results of preliminary antifungal test showed that all the title compounds exhibited potent antifungal activities to a certain extent. The activity of 4 compounds were more than 4 times as high as that of fluconazole and equal to that of ketoconazole against Candida albicans in vitro(MIC80 value≤0. 125 μg/ml). Conclusion:Introduction of a side chain containing 4-substituted acyl piperazin-l-yl into the main part of fluconazole has important influence on antifungal activities of title compounds.

  17. The Scope of Design Studying

    Institute of Scientific and Technical Information of China (English)

    JIN Yin; Ren Wenying

    2007-01-01

    This article trys to discuss the scope of design studying in two fields.Firstly, design has three meanings: wide design, art design and industrial design.Secondly, design studying has five contents: cultural, philosophical, methodological, produced and marketable trends.

  18. 40 CFR 1508.25 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Scope. 1508.25 Section 1508.25 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.25 Scope. Scope... statement. The scope of an individual statement may depend on its relationships to other statements (§§...

  19. Subject categories and scope descriptions

    International Nuclear Information System (INIS)

    This document is one in a series of publications known as the ETDE/INIS Joint Reference Series. It defines the subject categories and provides the scope descriptions to be used for categorization of the nuclear literature for the preparation of INIS and ETDE input by national and regional centres. Together with the other volumes of the INIS Reference Series it defines the rules, standards and practices and provides the authorities to be used in the International Nuclear Information System and ETDE. A complete list of the volumes published in the INIS Reference Series may be found on the inside front cover of this publication. This INIS/ETDE Reference Series document is intended to serve two purposes: to define the subject scope of the International Nuclear Information System (INIS) and the Energy Technology Data Exchange (ETDE) and to define the subject classification scheme of INIS and ETDE. It is thus the guide to the inputting centres in determining which items of literature should be reported, and in determining where the full bibliographic entry and abstract of each item should be included in INIS or ETDE database. Each category is identified by a category code consisting of three alphanumeric characters. A scope description is given for each subject category. The scope of INIS is the sum of the scopes of all the categories. With most categories cross references are provided to other categories where appropriate. Cross references should be of assistance in finding the appropriate category; in fact, by indicating topics that are excluded from the category in question, the cross references help to clarify and define the scope of the category to which they are appended. A Subject Index is included as an aid to subject classifiers, but it is only an aid and not a means for subject classification. It facilitates the use of this document, but is no substitute for the description of the scope of the subject categories

  20. Residential ventilation standards scoping study

    Energy Technology Data Exchange (ETDEWEB)

    McKone, Thomas E.; Sherman, Max H.

    2003-10-01

    The goals of this scoping study are to identify research needed to develop improved ventilation standards for California's Title 24 Building Energy Efficiency Standards. The 2008 Title 24 Standards are the primary target for the outcome of this research, but this scoping study is not limited to that timeframe. We prepared this scoping study to provide the California Energy Commission with broad and flexible options for developing a research plan to advance the standards. This document presents the findings of a scoping study commissioned by the Public Interest Energy Research (PIER) program of the California Energy Commission to determine what research is necessary to develop new residential ventilation requirements for California. This study is one of three companion efforts needed to complete the job of determining the ventilation needs of California residences, determining the bases for setting residential ventilation requirements, and determining appropriate ventilation technologies to meet these needs and requirements in an energy efficient manner. Rather than providing research results, this scoping study identifies important research questions along with the level of effort necessary to address these questions and the costs, risks, and benefits of pursuing alternative research questions. In approaching these questions and corresponding levels of effort, feasibility and timing were important considerations. The Commission has specified Summer 2005 as the latest date for completing this research in time to update the 2008 version of California's Energy Code (Title 24).

  1. Design, Synthesis, and Preclinical Evaluation of 4-Substituted-5-methyl-furo[2,3-d]pyrimidines as Microtubule Targeting Agents That Are Effective against Multidrug Resistant Cancer Cells.

    Science.gov (United States)

    Devambatla, Ravi Kumar Vyas; Namjoshi, Ojas A; Choudhary, Shruti; Hamel, Ernest; Shaffer, Corena V; Rohena, Cristina C; Mooberry, Susan L; Gangjee, Aleem

    2016-06-23

    The design, synthesis, and biological evaluations of eight 4-substituted 5-methyl-furo[2,3-d]pyrimidines are reported. Synthesis involved N(4)-alkylation of N-aryl-5-methylfuro[2,3-d]pyrimidin-4-amines, obtained from Ullmann coupling of 4-amino-5-methylfuro[2,3-d]pyrimidine and appropriate aryl iodides. Compounds 3, 4, and 9 showed potent microtubule depolymerizing activities, while compounds 6-8 had slightly lower potency. Compounds 4, 6, 7, and 9 inhibited tubulin assembly with IC50 values comparable to that of combretastatin A-4 (CA-4). Compounds 3, 4, and 6-9 circumvented Pgp and βIII-tubulin mediated drug resistance, mechanisms that can limit the efficacy of paclitaxel, docetaxel, and the vinca alkaloids. In the NCI 60-cell line panel, compound 3 exhibited GI50 values less than 10 nM in 47 of the cell lines. In an MDA-MB-435 xenograft model, compound 3 had statistically significant antitumor effects. The biological effects of 3 identify it as a novel, potent microtubule depolymerizing agent with antitumor activity. PMID:27213719

  2. 76 FR 10558 - Notice of Scope Rulings

    Science.gov (United States)

    2011-02-25

    ... of Scope Rulings, 75 FR 79339 (December 20, 2010). This current notice covers all scope rulings and... Threaded Rod from the People's Republic of China. Requestor: Elgin Fastener Group; hex collared stud is...

  3. 78 FR 32372 - Notice of Scope Rulings

    Science.gov (United States)

    2013-05-30

    ...). \\2\\ See Notice of Scope Rulings, 78 FR 9370 (February 8, 2013). Scope Rulings Made Between October 1... Republic of China Requestor: Tobacco Import USA (``TIU''); hookah charcoal tablets imported by TIU are...

  4. Anticonvulsant Profiles of Certain New 6-Aryl-9-substituted-6,9-diazaspiro-[4.5]decane-8,10-diones and 1-Aryl-4-substituted-1,4-diazaspiro[5.5]undecane-3,5-diones

    Directory of Open Access Journals (Sweden)

    Mohamed N. Aboul-Enein

    2014-09-01

    Full Text Available Synthesis and anticonvulsant potential of certain new 6-aryl-9-substituted-6,9-diazaspiro[4.5]decane-8,10-diones (6a–l and 1-aryl-4-substituted-1,4-diazaspiro[5.5] undecane-3,5-diones (6m–x are reported. The intermediates 1-[(aryl(cyanomethylamino] cycloalkanecarboxamides (3a–f were prepared via adopting Strecker synthesis on the proper cycloalkanone followed by partial hydrolysis of the obtained nitrile functionality and subsequent N-cyanomethylation. Compounds 3a–f were subjected to complete nitrile hydrolysis to give the respective carboxylic acid derivatives 4a–f which were cyclized under mild conditions to give the spiro compounds 5a–f. Ultimately, compounds 5a–f were alkylated or aralkylated to give the target compounds 6a–i and 6m–u. On the other hand, compounds 6j–l and 6v–x were synthesized from the intermediates 5a–f through alkylation, dehydration and finally tetrazole ring formation. Anticonvulsant screening of the target compounds 6a–x revealed that compound 6g showed an ED50 of 0.0043 mmol/kg in the scPTZ screen, being about 14 and 214 fold more potent than the reference drugs, Phenobarbital (ED50 = 0.06 mmol/kg and Ethosuximide (ED50 = 0.92 mmol/kg, respectively. Compound 6e exhibited an ED50 of 0.019 mmol/kg, being about 1.8 fold more potent than that of the reference drug, Diphenylhydantoin (ED50 = 0.034 mmol/kg in the MES screen. Interestingly, all the test compounds 6a–x did not show any minimal motor impairment at the maximum administered dose in the neurotoxicity screen.

  5. Anticonvulsant Profiles of Certain New 6-Aryl-9-substituted-6,9-diazaspiro-[4.5]decane-8,10-diones and 1-Aryl-4-substituted-1,4-diazaspiro[5.5]undecane-3,5-diones

    Science.gov (United States)

    Aboul-Enein, Mohamed N.; El-Azzouny, Aida A.; Attia, Mohamed I.; Maklad, Yousreya A.; Aboutabl, Mona E.; Ragab, Fatma; El-Hamid, Walaa H. A. Abd

    2014-01-01

    Synthesis and anticonvulsant potential of certain new 6-aryl-9-substituted-6,9-diazaspiro[4.5]decane-8,10-diones (6a–l) and 1-aryl-4-substituted-1,4-diazaspiro[5.5]undecane-3,5-diones (6m–x) are reported. The intermediates 1-[(aryl)(cyanomethyl)amino]cycloalkanecarboxamides (3a–f) were prepared via adopting Strecker synthesis on the proper cycloalkanone followed by partial hydrolysis of the obtained nitrile functionality and subsequent N-cyanomethylation. Compounds 3a–f were subjected to complete nitrile hydrolysis to give the respective carboxylic acid derivatives 4a–f which were cyclized under mild conditions to give the spiro compounds 5a–f. Ultimately, compounds 5a–f were alkylated or aralkylated to give the target compounds 6a–i and 6m–u. On the other hand, compounds 6j–l and 6v–x were synthesized from the intermediates 5a–f through alkylation, dehydration and finally tetrazole ring formation. Anticonvulsant screening of the target compounds 6a–x revealed that compound 6g showed an ED50 of 0.0043 mmol/kg in the scPTZ screen, being about 14 and 214 fold more potent than the reference drugs, Phenobarbital (ED50 = 0.06 mmol/kg) and Ethosuximide (ED50 = 0.92 mmol/kg), respectively. Compound 6e exhibited an ED50 of 0.019 mmol/kg, being about 1.8 fold more potent than that of the reference drug, Diphenylhydantoin (ED50 = 0.034 mmol/kg) in the MES screen. Interestingly, all the test compounds 6a–x did not show any minimal motor impairment at the maximum administered dose in the neurotoxicity screen. PMID:25250910

  6. 78 FR 9370 - Notice of Scope Rulings

    Science.gov (United States)

    2013-02-08

    ....225(o). \\2\\ See Notice of Scope Rulings, 77 FR 52313 (August 29, 2012). Scope Rulings Made Between... Republic of China-origin technical or crude glycine further processed in India is within the scope of the... the People's Republic of China Requestor: Lifetime Products, Inc.; its 34-inch square...

  7. 76 FR 31301 - Notice of Scope Rulings

    Science.gov (United States)

    2011-05-31

    ... lists after the close of the next calendar quarter. FOR FURTHER INFORMATION CONTACT: Julia Hancock, AD... Rulings, 76 FR 10558 (February 25, 2011). This current notice covers all scope rulings and... matches the exclusion language in the scope of the orders, is not within the scope of the antidumping...

  8. Scope: The Environmental Voice of World Science

    Science.gov (United States)

    Munn, R. E.; Cain, Melinda

    1977-01-01

    SCOPE is an international group that studies the effects of human activities on the environment and serves as a source of advice on environmental problems. Presently, SCOPE is involved with seven major projects that include biogeochemical cycles, ecotoxicology, and environmental monitoring. The structure and components of SCOPE are also discussed.…

  9. 36 CFR 223.130 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Scope. 223.130 Section 223... NATIONAL FOREST SYSTEM TIMBER Suspension and Debarment of Timber Purchasers § 223.130 Scope. (a) This... causes and procedures for debarment and suspension and for determining the scope, duration, and...

  10. 25 CFR 501.2 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Scope. 501.2 Section 501.2 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS PURPOSE AND SCOPE OF THIS CHAPTER § 501.2 Scope. (a) Tribes and other operators of class II and class III gaming operations on Indian lands shall...

  11. 36 CFR 251.50 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Scope. 251.50 Section 251.50... § 251.50 Scope. (a) All uses of National Forest System lands, improvements, and resources, except those... routine operation or maintenance activity within the scope of a statutory right-of-way for a...

  12. Making Patent Scopes Exceed the Technological Scopes of Scientific Inventions

    DEFF Research Database (Denmark)

    Beukel, Karin

    . The findings recast the relationship between science and patents as a process in which the way the transformation of the scientific invention is handled has an effect on the breadth of the patent scope. Unleashing patent scope surplus is dependent on processes related to abstraction and cognitive variety......This paper presents the results of a grounded theory study of the transformation of scientific discoveries into patented inventions. Using an algebraic interpretive approach, the narratives collected during interviews are analyzed as Bayesian inferences and the developed theory is tested......, which can be mobilized by patent experts with both an in-depth understanding of the scientific discovery, due to their educational background in the life sciences, and capabilities within the legal framework for patenting. More specifically, the findings reveal previously unreported aspects...

  13. Product Scope and Endogenous Fluctuations

    OpenAIRE

    Weder, Mark; Pavlov, Oscar

    2015-01-01

    Recent empirical evidence suggests that product creation is procyclical and it occurs largely within existing fi rms. Motivated by these findings, the current paper investigates the role of intrafi rm product scope choice in a general equilibrium economy with oligopolistic producers. We show that the multi-product nature of fi rms makes the economy signifi cantly more susceptible to sunspot equilibria. The estimated indeterminate model generates artifi cial business cycles that closely resemb...

  14. The Scope of Existential Spatiality

    OpenAIRE

    Dimitri Ginev

    2011-01-01

    The paper does not suggest an outline of a comprehensive theory of existential spatiality. Its aim is much moderate – to reveal those aspects of the constitution of meaning within the totality of being in the world which delineate the scope of the problematic under investigation. Since these aspects are addressed by various kinds of constitutional analysis of meaning, a special effort is devoted to overcoming discrepancies among three basic phenomenological discourses – hermeneutic phenomenol...

  15. The EarthScope Portal

    Science.gov (United States)

    Baru, C.; Ahern, T.; Anderson, G.; Behrends, K.; Casey, R.; Hoyt, B.; Kamb, L.; Lin, K.; Meertens, C.; Memon, A.; Muench, J.; Stolte, C.; Weertman, B.; Weiland, C.

    2007-12-01

    The EarthScope Portal is being developed in order to provide a unified, single-point of access to EarthScope data products from USArray, PBO, and SAFOD experiments. The portal will feature basic search and data access capabilities to allow users to discover and access EarthScope data using spatial, temporal, and other metadata- based search conditions. In this presentation, we will describe the features and design of the portal, which is being developed by a team consisting of GEON (Geosciences Network, http://www.geongrid.org), IRIS, UNAVCO, and Stanford. The portal search module invokes Web services developed by IRIS, UNAVCO, and Stanford to search for EarthScope data in the archives at each of these locations. The Web services provide information about all resources (data) that match the specified search conditions. Users will be able to select from the returned data sets, add selected data to a "data cart", and request the selected data to be packaged for download to the user. The initial services being defined are for "station discovery", to find which stations are available for specified spatial and temporal bounds, and "data discovery", to find the data sets that are available from the stations. Users will subsequently be able to choose the specific datasets, which will be assembled in a user "workspace" and available for download. The EarthScope Portal leverages the significant portal development efforts of the GEON Project at the San Diego Supercomputer Center, SDSC (http://portal.geongrid.org), and the development of Web services interfaces at the three data archive facilities. The portal is implemented using the open source GridSphere portal software infrastructure which supports the well-known Java portlet interface, viz. JSR 168 or the Portlet API. It uses a set of "core" portlets that have been developed in GEON for Data Registration, Search, and Workspace Services. We will provide a report on the current state of development of the Portal. A

  16. Work Breakdown Structure: A Tool for Software Project Scope Verification

    OpenAIRE

    Robert T. Hans

    2013-01-01

    Software project scope verification is a very important process in project scope management and it needs to be performed properly and thoroughly so as to avoid project rework and scope creep. Moreover, software scope verification is crucial in the process of delivering exactly what the customer requested and minimizing project scope changes. Well defined software scope eases the process of scope verification and contributes to project success. Furthermore, a deliverable-oriented WBS provides ...

  17. IDC Reengineering Phase 2 Project Scope.

    Energy Technology Data Exchange (ETDEWEB)

    Harris, James M.

    2015-02-01

    This report provides a brief description of the scope of the IDC Reengineering Phase 2 project. It describes the goals and objectives of reengineering, the system definition, and the technical scope of the system. REVISIONS Version Date Author/Team Revision Description Authorized by 1.0 9/25/2014 SNL IDC Reengineering Team Unlimited Release for I2 M. Harris 1.1 28/01/2015 IDC Reengineering Team Align with previous IDC scope document E. Tomuta

  18. 46 CFR 162.050-1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... APPROVAL ENGINEERING EQUIPMENT Pollution Prevention Equipment § 162.050-1 Scope. (a) This subpart contains... facility authorized to conduct approval tests; (5) Marking requirements; and (6) Factory...

  19. 77 FR 63309 - Constitution Pipeline Company, LLC; Notice of Public Scoping Meeting and Extension of Scoping...

    Science.gov (United States)

    2012-10-16

    ... Energy Regulatory Commission Constitution Pipeline Company, LLC; Notice of Public Scoping Meeting and Extension of Scoping Period for the Planned Constitution Pipeline Project On October 24, 2012, the Federal... Constitution Pipeline Company's (Constitution) Constitution Pipeline Project. This notice also extends...

  20. 10 CFR 850.1 - Scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Scope. 850.1 Section 850.1 Energy DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM General Provisions § 850.1 Scope. This part provides for establishment of a chronic beryllium disease prevention program (CBDPP) that supplements and is deemed...

  1. 44 CFR 351.2 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope. 351.2 Section 351.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS RADIOLOGICAL EMERGENCY PLANNING AND PREPAREDNESS General § 351.2 Scope. The emergency planning...

  2. 21 CFR 1010.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope. 1010.1 Section 1010.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR ELECTRONIC PRODUCTS: GENERAL General Provisions § 1010.1 Scope. The standards...

  3. 78 FR 59653 - Notice of Scope Rulings

    Science.gov (United States)

    2013-09-27

    ..., and June 30, 2013. We intend to publish future lists after the close of the next calendar quarter...). \\2\\ See Notice of Scope Rulings, 78 FR 42934 (July 18, 2013). Scope Rulings Made Between April 1... together as a complete set; April 19, 2013. A-570-941: Certain Kitchen Appliance Shelving and Racks...

  4. 41 CFR 128-1.8000 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope. 128-1.8000 Section 128-1.8000 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.80-Seismic Safety Program § 128-1.8000 Scope. This...

  5. 19 CFR 134.0 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Scope. 134.0 Section 134.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING § 134.0 Scope. This part sets forth regulations implementing the country of origin...

  6. 78 FR 42934 - Notice of Scope Rulings

    Science.gov (United States)

    2013-07-18

    ...). \\2\\ See Notice of Scope Rulings, 78 FR 32372 (May 30, 2013). Scope Rulings Made Between January 1... duty order; March 7, 2013. A-570-970 and C-570-971: Multilayered Wood Flooring From the People's... orders, and ASC's ladders, models ASE, ASH, and DJX3-W, and strip door mounting brackets are within...

  7. 49 CFR 536.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... OF TRANSPORTATION TRANSFER AND TRADING OF FUEL ECONOMY CREDITS § 536.1 Scope. This part establishes... manufacturers wishing to transfer fuel economy credits between their fleets and for manufacturers and other... 49 Transportation 6 2010-10-01 2010-10-01 false Scope. 536.1 Section 536.1 Transportation...

  8. 19 CFR 177.0 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Scope. 177.0 Section 177.0 Customs Duties U.S...) ADMINISTRATIVE RULINGS § 177.0 Scope. This part relates to the issuance of rulings to importers and other... Act of 1930, as amended). Nor do the provisions of part 177 apply to requests for decisions of...

  9. 32 CFR 516.27 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Scope. 516.27 Section 516.27 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Individual Liability § 516.27 Scope. This subpart guidance when DA personnel, as a result of...

  10. 32 CFR 516.38 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Scope. 516.38 Section 516.38 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Environmental Litigation § 516.38 Scope. This subpart contains guidance, policies, and...

  11. The Scope of the 1992 Water Convention

    NARCIS (Netherlands)

    Merkouris, Panos; Fitzmaurice, Malgosia; Tanzi, Attila; McIntyre, Owen; Kolliopoulos, Alexandros; Rieu-Clarke, Alistair; Kinna, Rémy

    2015-01-01

    This Chapter will be devoted to the scope of the 1992 Water Convention. Its focus will be the general legal framework of the Convention, as the detailed analysis of its normative scope and the overview of its underlying legal principles will be discussed elsewhere in this publication. Suffice to say

  12. Anger perceptually and conceptually narrows cognitive scope.

    Science.gov (United States)

    Gable, Philip A; Poole, Bryan D; Harmon-Jones, Eddie

    2015-07-01

    For the last 50 years, research investigating the effect of emotions on scope of cognitive processing was based on models proposing that affective valence determined cognitive scope. More recently, our motivational intensity model suggests that this past work had confounded valence with motivational intensity. Research derived from this model supports the idea that motivational intensity, rather than affective valence, explains much of the variance emotions have on cognitive scope. However, the motivational intensity model is limited in that the empirical work has examined only positive affects high in approach and negative affects high in avoidance motivation. Thus, perhaps only approach-positive and avoidance-negative states narrow cognitive scope. The present research was designed to clarify these conceptual issues by examining the effect of anger, a negatively valenced approach-motivated state, on cognitive scope. Results revealed that anger narrowed attentional scope relative to a neutral state and that attentional narrowing to anger was similar to the attentional narrowing caused by high approach-motivated positive affects (Study 1). This narrowing of attention was related to trait approach motivation (Studies 2 and Study 3). Anger also narrowed conceptual cognitive categorization (Study 4). Narrowing of categorization related to participants' approach motivation toward anger stimuli. Together, these results suggest that anger, an approach-motivated negative affect, narrows perceptual and conceptual cognitive scope. More broadly, these results support the conceptual model that motivational intensity per se, rather than approach-positive and avoidance-negative states, causes a narrowing of cognitive scope.

  13. 40 CFR 21.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Scope. 21.1 Section 21.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL SMALL BUSINESS § 21.1 Scope. This part establishes procedures for the issuance by EPA of the statements, referred to in section 7(g) of the Small Business...

  14. 34 CFR 601.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Scope. 601.1 Section 601.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION INSTITUTION AND LENDER REQUIREMENTS RELATING TO EDUCATION LOANS General § 601.1 Scope. This...

  15. 19 CFR 123.0 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Scope. 123.0 Section 123.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS RELATIONS WITH CANADA AND MEXICO § 123.0 Scope. This part contains special regulations pertaining to Customs procedures at the Canadian and...

  16. 41 CFR 60-3.2 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Scope. 60-3.2 Section 60-3.2 Public Contracts and Property Management Other Provisions Relating to Public Contracts OFFICE OF... GUIDELINES ON EMPLOYEE SELECTION PROCEDURES (1978) General Principles § 60-3.2 Scope. A. Application...

  17. 49 CFR 192.501 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.501 Section 192.501 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Test Requirements § 192.501 Scope. This...

  18. 40 CFR 142.3 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Scope. 142.3 Section 142.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS IMPLEMENTATION General Provisions § 142.3 Scope. (a) Except...

  19. 42 CFR 423.150 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.150 Section 423.150 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... § 423.150 Scope. This subpart sets forth the requirements relating to the following: (a)...

  20. 28 CFR 90.60 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Scope. 90.60 Section 90.60 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) VIOLENCE AGAINST WOMEN Arrest Policies in Domestic Violence Cases § 90.60 Scope. This subpart sets forth the statutory framework of the Violence Against Women...

  1. 40 CFR 81.11 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Scope. 81.11 Section 81.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.11 Scope....

  2. 32 CFR 726.2 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 726.2 Section 726.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL PAYMENTS OF AMOUNTS DUE MENTALLY INCOMPETENT MEMBERS OF THE NAVAL SERVICE § 726.2 Scope. (a) The Secretary of the Navy has authority...

  3. 28 CFR 92.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Scope. 92.1 Section 92.1 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) OFFICE OF COMMUNITY ORIENTED POLICING SERVICES (COPS) Police Corps Eligibility and Selection Criteria § 92.1 Scope. This subpart sets forth guidance on...

  4. 49 CFR 191.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ..., operation, and maintenance under 49 CFR 190.9. (3) Pipelines on the Outer Continental Shelf upstream of the... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 191.1 Section 191.1 Transportation Other...; ANNUAL REPORTS, INCIDENT REPORTS, AND SAFETY-RELATED CONDITION REPORTS § 191.1 Scope. (a) This...

  5. 40 CFR 79.30 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Scope. 79.30 Section 79.30 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGISTRATION OF FUELS AND FUEL ADDITIVES Designation of Fuels and Additives § 79.30 Scope. Fuels and...

  6. 49 CFR 190.301 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 190.301 Section 190.301 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PROCEDURES Procedures for Adoption of Rules § 190.301 Scope. This subpart prescribes general...

  7. 42 CFR 424.60 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 424.60 Section 424.60 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM CONDITIONS FOR MEDICARE PAYMENT To Whom Payment is Made in Special Situations § 424.60 Scope. (a)...

  8. 48 CFR 939.7000 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope. 939.7000 Section 939.7000 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Implementing DOE Policies and Procedures 939.7000 Scope. This part...

  9. 32 CFR 761.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 761.1 Section 761.1 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY ISLANDS UNDER NAVY JURISDICTION NAVAL DEFENSIVE SEA... PACIFIC ISLANDS Introduction § 761.1 Scope. (a) This part provides regulations governing the entry...

  10. 42 CFR 423.1968 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.1968 Section 423.1968 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Review § 423.1968 Scope. This subpart sets forth the requirements relating to the following: (a) Part...

  11. 36 CFR 261.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Scope. 261.1 Section 261.1 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PROHIBITIONS General Prohibitions § 261.1 Scope. (a) The prohibitions in this part apply, except as otherwise provided, when: (1)...

  12. 42 CFR 424.100 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 424.100 Section 424.100 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Nonparticipating Hospital § 424.100 Scope. This subpart sets forth procedures and criteria that are followed...

  13. 49 CFR 192.51 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.51 Section 192.51 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION...: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.51 Scope. This subpart prescribes minimum...

  14. 49 CFR 193.2051 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2051 Section 193.2051 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Siting Requirements § 193.2051 Scope. Each LNG facility designed,...

  15. 49 CFR 192.101 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.101 Section 192.101 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Pipe Design § 192.101 Scope. This subpart...

  16. 49 CFR 195.48 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.48 Section 195.48 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION... Annual, Accident, and Safety-Related Condition Reporting § 195.48 Scope. This subpart...

  17. 40 CFR 80.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Scope. 80.1 Section 80.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES General Provisions § 80.1 Scope. (a) This part prescribes regulations for the control...

  18. 42 CFR 415.100 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 415.100 Section 415.100 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... § 415.100 Scope. This subpart implements section 1887(a)(1)(A) of the Act by providing...

  19. 42 CFR 424.120 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 424.120 Section 424.120 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE....120 Scope. This subpart sets forth the conditions for payment for services furnished in a...

  20. 49 CFR 195.100 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.100 Section 195.100 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Design Requirements § 195.100 Scope. This subpart prescribes minimum design requirements for...

  1. 42 CFR 415.150 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 415.150 Section 415.150 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... RESIDENTS IN CERTAIN SETTINGS Physician Services in Teaching Settings § 415.150 Scope. This subpart...

  2. 49 CFR 195.300 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.300 Section 195.300 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Pressure Testing § 195.300 Scope. This subpart prescribes minimum requirements for the...

  3. 49 CFR 192.271 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.271 Section 192.271 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... Scope. (a) This subpart prescribes minimum requirements for joining materials in pipelines, other...

  4. 49 CFR 193.2701 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2701 Section 193.2701 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Personnel Qualifications and Training § 193.2701 Scope. This subpart...

  5. 32 CFR 756.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 756.1 Section 756.1 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS PROCEDURES FOR PROCESSING CLAIMS INVOLVING NON-APPROPRIATED FUND ACTIVITIES AND THEIR EMPLOYEES § 756.1 Scope. This part explains how to...

  6. 49 CFR 195.200 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.200 Section 195.200 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.200 Scope. This subpart prescribes minimum requirements for constructing...

  7. 42 CFR 423.251 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.251 Section 423.251 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE...; Plan Approval § 423.251 Scope. This section sets forth the requirements and limitations on...

  8. 42 CFR 423.301 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.301 Section 423.301 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Prescription Drug Coverage § 423.301 Scope. This subpart sets forth rules for the calculation and payment...

  9. 36 CFR 228.2 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Scope. 228.2 Section 228.2 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE MINERALS Locatable Minerals § 228.2 Scope. These regulations apply to operations hereafter conducted under the United...

  10. 42 CFR 424.500 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 424.500 Section 424.500 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Privileges § 424.500 Scope. The provisions of this subpart contain the requirements for enrollment,...

  11. 32 CFR 734.2 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 734.2 Section 734.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL GARNISHMENT OF PAY OF NAVAL MILITARY AND CIVILIAN PERSONNEL FOR COLLECTION OF CHILD SUPPORT AND ALIMONY § 734.2 Scope. The provisions of this...

  12. 40 CFR 172.20 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope. 172.20 Section 172.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS EXPERIMENTAL USE PERMITS State Issuance of Experimental Use Permits § 172.20 Scope. This subpart sets forth...

  13. 32 CFR 755.2 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 755.2 Section 755.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS CLAIMS FOR INJURIES TO PROPERTY UNDER ARTICLE 139 OF THE UNIFORM CODE OF MILITARY JUSTICE § 755.2 Scope. This chapter provides for...

  14. 32 CFR 752.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 752.1 Section 752.1 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS ADMIRALTY CLAIMS § 752.1 Scope. This part applies to admiralty-tort claims. These include claims against the United States for damage caused by...

  15. 49 CFR 193.2101 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2101 Section 193.2101 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Design § 193.2101 Scope. (a) Each LNG facility designed after March 31, 2000...

  16. 31 CFR 800.101 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Scope. 800.101 Section 800.101 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF INVESTMENT... FOREIGN PERSONS General § 800.101 Scope. The regulations in this part implement section 721 of title...

  17. 40 CFR 152.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope. 152.1 Section 152.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES General Provisions § 152.1 Scope. (a) Part 152 sets forth...

  18. 49 CFR 199.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 199.1 Section 199.1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING General § 199.1 Scope....

  19. 49 CFR 193.2901 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2901 Section 193.2901 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2901 Scope. This subpart prescribes requirements for security...

  20. 49 CFR 192.551 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.551 Section 192.551 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Uprating § 192.551 Scope. This subpart...

  1. 49 CFR 193.2301 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2301 Section 193.2301 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Construction § 193.2301 Scope. Each LNG facility constructed after March 31,...

  2. 40 CFR 165.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope. 165.1 Section 165.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL General § 165.1 Scope. The part 165 regulations establish standards and requirements...

  3. 40 CFR 152.100 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope. 152.100 Section 152.100 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Agency Review of Applications § 152.100 Scope. (a) The Agency...

  4. 40 CFR 88.201-94 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Scope. 88.201-94 Section 88.201-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.201-94 Scope. Applicability. The requirements of this...

  5. 40 CFR 180.2000 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope. 180.2000 Section 180.2000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND... Exemption From a Tolerance § 180.2000 Scope. This subpart sets forth the pesticide chemicals for use...

  6. 31 CFR 1.8 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Scope. 1.8 Section 1.8 Money and Finance: Treasury Office of the Secretary of the Treasury DISCLOSURE OF RECORDS Other Disclosure Provisions § 1.8 Scope. The regulations in this subpart concern access to information and records other...

  7. 49 CFR 1151.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Scope. 1151.1 Section 1151.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE FEEDER RAILROAD DEVELOPMENT PROGRAM § 1151.1 Scope. This part governs...

  8. 42 CFR 424.50 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 424.50 Section 424.50 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM CONDITIONS FOR MEDICARE PAYMENT To Whom Payment Is Ordinarily Made § 424.50 Scope. (a) This subpart...

  9. 40 CFR 152.160 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope. 152.160 Section 152.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Classification of Pesticides § 152.160 Scope. (a) Types...

  10. 42 CFR 423.500 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.500 Section 423.500 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... sponsors § 423.500 Scope. This subpart sets forth application procedures and contracts with Part D...

  11. 49 CFR 377.201 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Scope. 377.201 Section 377.201 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION... Forwarders § 377.201 Scope. (a) General. These regulations apply to the extension of credit in...

  12. 49 CFR 195.501 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.501 Section 195.501 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Qualification of Pipeline Personnel § 195.501 Scope. (a) This subpart prescribes the...

  13. 49 CFR 192.351 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.351 Section 192.351 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.351 Scope. This subpart prescribes minimum requirements for installing customer meters,...

  14. 31 CFR 8.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Scope. 8.1 Section 8.1 Money and Finance: Treasury Office of the Secretary of the Treasury PRACTICE BEFORE THE BUREAU OF ALCOHOL, TOBACCO AND FIREARMS General Requirements § 8.1 Scope. This part contains rules governing the recognition...

  15. 49 CFR 192.221 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.221 Section 192.221 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Welding of Steel in Pipelines § 192.221 Scope. (a)...

  16. 49 CFR 1118.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Scope. 1118.1 Section 1118.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE PROCEDURES IN INFORMAL PROCEEDINGS BEFORE EMPLOYEE BOARDS § 1118.1 Scope. The rules...

  17. 49 CFR 198.31 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 198.31 Section 198.31 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION... PROGRAMS Adoption of One-Call Damage Prevention Program § 198.31 Scope. This subpart implements parts...

  18. 40 CFR 81.400 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Scope. 81.400 Section 81.400 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF... Visibility Is an Important Value § 81.400 Scope. Subpart D, §§ 81.401 through 81.437, lists those...

  19. 49 CFR 195.400 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.400 Section 195.400 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Operation and Maintenance § 195.400 Scope. This subpart prescribes minimum requirements...

  20. 49 CFR 192.301 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.301 Section 192.301 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... Lines and Mains § 192.301 Scope. This subpart prescribes minimum requirements for...

  1. 31 CFR 103.80 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Scope. 103.80 Section 103.80 Money and Finance: Treasury Regulations Relating to Money and Finance FINANCIAL RECORDKEEPING AND REPORTING OF CURRENCY AND FOREIGN TRANSACTIONS Administrative Rulings § 103.80 Scope. This subpart...

  2. 49 CFR 192.451 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.451 Section 192.451 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Requirements for Corrosion Control § 192.451 Scope....

  3. 41 CFR 51-8.2 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Scope. 51-8.2 Section 51-8.2 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE... § 51-8.2 Scope. (a) These regulations shall apply to all final determinations made by the...

  4. 42 CFR 423.851 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.851 Section 423.851 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Prescription Drug Plans) § 423.851 Scope. This subpart sets forth—the rights of beneficiaries to a choice of...

  5. 49 CFR 198.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 198.1 Section 198.1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION... PROGRAMS General § 198.1 Scope. This part prescribes regulations governing grants-in-aid for State...

  6. 49 CFR 1121.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Scope. 1121.1 Section 1121.1 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE RAIL EXEMPTION PROCEDURES § 1121.1 Scope. These procedures generally govern...

  7. 25 CFR 571.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Scope. 571.1 Section 571.1 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR COMPLIANCE AND ENFORCEMENT PROVISIONS MONITORING AND INVESTIGATIONS General § 571.1 Scope. This part sets forth general procedures governing Commission monitoring...

  8. 32 CFR 751.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scope. 751.1 Section 751.1 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS PERSONNEL CLAIMS REGULATIONS Claims Against the United States § 751.1 Scope. This part prescribes procedures and substantive bases...

  9. 49 CFR 192.801 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.801 Section 192.801 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Qualification of Pipeline Personnel § 192.801 Scope....

  10. 31 CFR 15.737-1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Scope. 15.737-1 Section 15.737-1 Money and Finance: Treasury Office of the Secretary of the Treasury POST EMPLOYMENT CONFLICT OF INTEREST General Provisions § 15.737-1 Scope. This part contains rules governing discipline of a former officer...

  11. 42 CFR 424.30 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 424.30 Section 424.30 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM CONDITIONS FOR MEDICARE PAYMENT Claims for Payment § 424.30 Scope. This subpart sets forth the...

  12. 49 CFR 195.0 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.0 Section 195.0 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION... General § 195.0 Scope. This part prescribes safety standards and reporting requirements for...

  13. 49 CFR 192.601 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.601 Section 192.601 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Operations § 192.601 Scope. This subpart...

  14. 42 CFR 423.558 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.558 Section 423.558 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE..., and Reconsiderations § 423.558 Scope. (a) This subpart sets forth the requirements relating to...

  15. 49 CFR 193.2401 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2401 Section 193.2401 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Equipment § 193.2401 Scope. After March 31, 2000, each new, replaced,...

  16. 49 CFR 193.2501 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2501 Section 193.2501 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Operations § 193.2501 Scope. This subpart prescribes requirements for...

  17. 49 CFR 396.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Scope. 396.1 Section 396.1 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS INSPECTION, REPAIR, AND MAINTENANCE § 396.1 Scope....

  18. 42 CFR 423.452 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.452 Section 423.452 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Drug Coverage § 423.452 Scope. This section sets forth the application of Part D rules to Part C...

  19. 28 CFR 92.7 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Scope. 92.7 Section 92.7 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) OFFICE OF COMMUNITY ORIENTED POLICING SERVICES (COPS) Police Recruitment Program Guidelines § 92.7 Scope. (a) The Police Recruitment program offers funds to...

  20. 49 CFR 192.141 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.141 Section 192.141 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Design of Pipeline Components § 192.141 Scope....

  1. 49 CFR 192.701 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 192.701 Section 192.701 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Maintenance § 192.701 Scope. This subpart...

  2. 49 CFR 1120.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... accounting instruction number 27 of the Board's Uniform System of Accounts (49 CFR Part 1207). ... 49 Transportation 8 2010-10-01 2010-10-01 false Scope. 1120.1 Section 1120.1 Transportation Other... RULES OF PRACTICE USE OF 1977-1978 STUDY OF MOTOR CARRIER PLATFORM HANDLING FACTORS § 1120.1 Scope....

  3. 48 CFR 970.1707-1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope. 970.1707-1 Section 970.1707-1 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Special Contracting Methods 970.1707-1 Scope. Pursuant...

  4. 42 CFR 417.140 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 417.140 Section 417.140 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Application for Federal Qualification § 417.140 Scope. This subpart sets forth— (a) The requirements for—...

  5. 49 CFR 193.2601 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2601 Section 193.2601 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Maintenance § 193.2601 Scope. This subpart prescribes requirements...

  6. 16 CFR 316.1 - Scope.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Scope. 316.1 Section 316.1 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CAN-SPAM RULE § 316.1 Scope. This part implements the Controlling the Assault of Non-Solicited Pornography and Marketing Act of...

  7. Common Cause Abduction : Its Scope and Limits

    NARCIS (Netherlands)

    Dziurosz-Serafinowicz, Patryk

    2012-01-01

    Patryk Dziurosz-Serafmowicz, Common Cause Abduction: Its Scope and Limits This article aims to analyze the scope and limits of common cause abduction which is a version of explanatory abduction based on Hans Reichenbach's Principle of the Common Cause. First, it is argued that common cause abduction

  8. 21 CFR 866.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope. 866.1 Section 866.1 Food and Drugs FOOD AND... MICROBIOLOGY DEVICES General Provisions § 866.1 Scope. (a) This part sets forth the classification of immunology and microbiology devices intended for human use that are in commercial distribution. (b)...

  9. 45 CFR 12.2 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Scope. 12.2 Section 12.2 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION DISPOSAL AND UTILIZATION OF SURPLUS REAL PROPERTY FOR PUBLIC HEALTH PURPOSES § 12.2 Scope. This part is applicable to surplus real property located within any State which is appropriate...

  10. SYNTHESIS, CHARACTERIZATION AND BIOCIDAL ACTIVITY OF NOVEL HALOGENATED - 4-[(SUBSTITUTED-BENZOTHIAZOL-2-YL HYDRAZONO]-2-(SUBSTITUTED-PHENYL-5-METHYL /ETHOXY -2,4-DIHYDRO-PYRAZOL-3-ONE DERIVATIVES Synthese, Charakterisierung und biozide Aktivität NOVEL HALOGENIERTEN - 4 - [(substituiertes-benzothiazol-2-YL hydrazono] -2 -(Substituiertes Phenyl-5-Methyl / ETHOXY -2,4-DIHYDRO-pyrazol-3-ONE DERIVATE

    Directory of Open Access Journals (Sweden)

    V. Khatri, K. Sharma, V. Sareen, D. Shinde and S. Sareen

    2012-04-01

    Full Text Available Some new 4-[(substituted-benzothiazol-2-ylhydrazono]-2-(substituted-phenyl-5- methyl/ethoxy-2,4-dihydro-pyrazol-3-one(4 have been synthesized by reacting substituted 2- amino benzothiazol (1 with acetoacetic ester and malonic ester (2. 2-[(substituted-benzothiazol- 2-ylhydrazono]-3-oxo-butyric acid ethyl ester and 2-[(substituted-benzothiazol-2- ylhydrazono]- malonic acid diethyl ester (3 react with different hydrazines to give the title compounds(4. These compounds are evaluated for their antifungal and insecticidal activity. The structures of all these compounds have been confirmed by IR, 1H NMR, mass spectra and elemental analysis data.

  11. 45 CFR 673.2 - Scope.

    Science.gov (United States)

    2010-10-01

    ... of the Antarctic Treaty. ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Scope. 673.2 Section 673.2 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION ANTARCTIC...

  12. 23 CFR 1350.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INCENTIVE GRANT CRITERIA FOR MOTORCYCLIST SAFETY PROGRAM § 1350.1 Scope. This part establishes criteria, in accordance with section 2010 of the... single- and multi-vehicle crashes involving motorcyclists....

  13. 14 CFR 1221.100 - Scope.

    Science.gov (United States)

    2010-01-01

    ..., and the Agency's Unified Visual Communications System § 1221.100 Scope. This subpart sets forth the... Unified Visual Communications System and prescribes the policy and guidelines for implementation of...

  14. 48 CFR 23.1000 - Scope.

    Science.gov (United States)

    2010-10-01

    ... WORKPLACE Federal Compliance With Right-To-Know Laws and Pollution Prevention Requirements 23.1000 Scope...) Compliance with right-to-know laws and pollution prevention requirements; (b) Implementation of...

  15. 49 CFR 215.101 - Scope.

    Science.gov (United States)

    2010-10-01

    ... TRANSPORTATION RAILROAD FREIGHT CAR SAFETY STANDARDS Freight Car Components § 215.101 Scope. This subpart contains safety requirements prohibiting a railroad from placing or continuing in service a freight car that has certain defective components. Suspension System...

  16. Scope of nanotechnology in modern textiles

    Science.gov (United States)

    This review article demonstrates the scope and applications of nanotechnology towards modification and development of advanced textile fibers, yarns and fabrics and their processing techniques. Basically, it summarizes the recent advances made in nanotechnology and its applications to cotton textil...

  17. 12 CFR 303.220 - Scope.

    Science.gov (United States)

    2010-01-01

    ... of the FDI Act (Consent to Service of Persons Convicted of Certain Criminal Offenses) § 303.220 Scope. This subpart covers applications under section 19 of the FDI Act (12 U.S.C. 1829). Pursuant to...

  18. 21 CFR 343.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ... ANALGESIC, ANTIPYRETIC, AND ANTIRHEUMATIC DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE General Provisions § 343.1 Scope. (a) An over-the-counter analgesic-antipyretic drug product in a form suitable for...

  19. 30 CFR 90.1 - Scope.

    Science.gov (United States)

    2010-07-01

    ... STANDARDS-COAL MINERS WHO HAVE EVIDENCE OF THE DEVELOPMENT OF PNEUMOCONIOSIS General § 90.1 Scope. This Part... areas of underground coal mines and who have evidence of the development of pneumoconiosis to work in...

  20. 7 CFR 610.2 - Scope.

    Science.gov (United States)

    2010-01-01

    ... the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE CONSERVATION OPERATIONS TECHNICAL ASSISTANCE Conservation Operations § 610.2 Scope. (a) Conservation operations, including technical assistance, is the basic soil and water conservation program...

  1. 14 CFR 171.201 - Scope.

    Science.gov (United States)

    2010-01-01

    ... FACILITIES NON-FEDERAL NAVIGATION FACILITIES VHF Marker Beacons § 171.201 Scope. (a) This subpart sets forth minimum requirements for the approval and operation of non-Federal VHF marker beacon facilities that...

  2. Insensitivity to Scope in Contingent Valuation Studies

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Lindholt, Jes Sanddal; Gyrd-Hansen, Dorte

    2012-01-01

    relationships were identified. One exception was the influence of more detailed information, which was positively associated with willingness to pay and negatively associated with scope sensitivity. Conclusion: Possible explanations for scope insensitivity are discussed; if cognitive limitations, emotional load...... focus more on extracting the underlying motives for the stated preferences in order to appropriately deal with responses that are seemingly irrational, and which may lead to imprecise welfare estimates....

  3. Solomon Islands: Malaita Hub scoping report

    OpenAIRE

    Schwarz, A.M.; Andrew, N.; Govan, H.; Harohau, D.; Oeta, J.

    2013-01-01

    The CGIAR Research Program (CRP) Aquatic Agricultural Systems (AAS) will target five countries, including Solomon Islands. The proposed hubs for Solomon Islands were to cover most provinces, referencing the Western, Central and Eastern regions. Scoping of the initial ‘Central’ hub was undertaken in Guadalcanal, Malaita and Central Islands provinces and this report details findings from all three. As scoping progressed however, it was agreed that, based on the AAS context and priority need...

  4. 48 CFR 36.302 - Scope of work.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Scope of work. 36.302... Scope of work. The agency shall develop, either in-house or by contract, a scope of work that defines the project and states the Government's requirements. The scope of work may include criteria...

  5. Work Breakdown Structure: A Tool for Software Project Scope Verification

    Directory of Open Access Journals (Sweden)

    Robert T. Hans

    2013-07-01

    Full Text Available Software project scope verification is a very important process in project scope management and it needsto be performed properly and thoroughly so as to avoid project rework and scope creep. Moreover,software scope verification is crucial in the process of delivering exactly what the customer requested andminimizing project scope changes. Well defined software scope eases the process of scope verification andcontributes to project success. Furthermore, a deliverable-oriented WBS provides a road map to a welldefined software scope of work. It is on the basis of this that this paper extends the use of deliverableorientedWBS to that of scope verification process. This paper argues that a deliverable-oriented WBS is atool for software scope verification

  6. 3,3'-Bis(trisarylsilyl)-substituted binaphtholate rare earth metal catalysts for asymmetric hydroamination.

    Science.gov (United States)

    Gribkov, Denis V; Hultzsch, Kai C; Hampel, Frank

    2006-03-22

    Chiral 3,3'-bis(trisarylsilyl)-substituted binaphtholate rare earth metal complexes (R)-[Ln{Binol-SiAr3}(o-C6H4CH2NMe2)(Me2NCH2Ph)] (Ln = Sc, Lu, Y; Binol-SiAr3 = 3,3'-bis(trisarylsilyl)-2,2'-dihydroxy-1,1'-binaphthyl; Ar = Ph (2-Ln), 3,5-xylyl (3-Ln)) and (R)-[La{Binol-Si(3,5-xylyl)3}{E(SiMe3)2}(THF)2] (E = CH (4a), N (4b)) are accessible via facile arene, alkane, and amine elimination. They are efficient catalysts for the asymmetric hydroamination/cyclization of aminoalkenes, giving TOF of up to 840 h(-1) at 25 degrees C for 2,2-diphenyl-pent-4-enylamine (5c) using (R)-2-Y. Enantioselectivities of up to 95% ee were achieved in the cyclization of 5c with (R)-2-Sc. The reactions show apparently zero-order rate dependence on substrate concentration and first-order rate dependence on catalyst concentration, but rates depend on total amine concentrations. Activation parameters for the cyclization of pent-4-enylamine using (R)-2-Y (deltaH(S)(double dagger) = 57.4(0.8) kJ mol(-1) and deltaS(S)(double dagger) = -102(3) J K(-1) mol(-1); deltaH(R)(double dagger) = 61.5(0.7) kJ mol(-1) and deltaS(R)(double dagger) = -103(3) J K(-1) mol(-1)) indicate a highly organized transition state. The binaphtholate catalysts were also applied to the kinetic resolution of chiral alpha-substituted aminoalkenes with resolution factors f of up to 19. The 2,5-disubstituted aminopentenes were formed in 7:1 to > or = 50:1 trans diastereoselectivity, depending on the size of the alpha-substituent of the aminoalkene. Rate studies with (S)-1-phenyl-pent-4-enylamine ((S)-15e) gave the activation parameters for the matching (deltaH(double dagger) = 52.2(2.8) kJ mol(-1), deltaS(double dagger) = -127(8) J K(-1) mol(-1) using (S)-2-Y) and mismatching (deltaH(double dagger) = 57.7(1.3) kJ mol(-1), deltaS(double dagger) = -126(4) J K(-1) mol(-1) using (R)-2-Y) substrate/catalyst combination. The absolute configuration of the Mosher amide of (2S)-2-methyl-4,4-diphenyl-pyrrolidine and (2R)-methyl-(5S

  7. Harry Potter and the sorcerer's scope: latent scope biases in explanatory reasoning.

    Science.gov (United States)

    Khemlani, Sangeet S; Sussman, Abigail B; Oppenheimer, Daniel M

    2011-04-01

    What makes a good explanation? We examine the function of latent scope, i.e., the number of unobserved phenomena that an explanation can account for. We show that individuals prefer narrow latent scope explanations-those that account for fewer unobserved effects-to broader explanations. In Experiments 1a-d, participants found narrow latent scope explanations to be both more satisfying and more likely. In Experiment 2 we directly manipulated base rate information and again found a preference for narrow latent scope explanations. Participants in Experiment 3 evaluated more natural explanations of unexpected observations, and again displayed a bias for narrow latent scope explanations. We conclude by considering what this novel bias tells us about how humans evaluate explanations and engage in causal reasoning. PMID:21264612

  8. Harry Potter and the sorcerer's scope: latent scope biases in explanatory reasoning.

    Science.gov (United States)

    Khemlani, Sangeet S; Sussman, Abigail B; Oppenheimer, Daniel M

    2011-04-01

    What makes a good explanation? We examine the function of latent scope, i.e., the number of unobserved phenomena that an explanation can account for. We show that individuals prefer narrow latent scope explanations-those that account for fewer unobserved effects-to broader explanations. In Experiments 1a-d, participants found narrow latent scope explanations to be both more satisfying and more likely. In Experiment 2 we directly manipulated base rate information and again found a preference for narrow latent scope explanations. Participants in Experiment 3 evaluated more natural explanations of unexpected observations, and again displayed a bias for narrow latent scope explanations. We conclude by considering what this novel bias tells us about how humans evaluate explanations and engage in causal reasoning.

  9. Psycholinguistic Evidence for Inverse Scope in Korean.

    Science.gov (United States)

    Lee, Sunyoung; O'Grady, William

    2016-08-01

    We use experimental data to shed light on the ongoing question of whether Korean allows inverse scope interpretation in sentences containing an indefinite subject and a universally quantified direct object (e.g., 'Someone bought each loaf of bread at the bakery'). The results of an off-line acceptability judgment task (n = 38) and an online self-paced reading task (n [Formula: see text] 22) indicate that inverse scope interpretations are in fact permitted in Korean as a secondary option, as is also the case in English. We argue that the dispreference for the inverse scope reading reflects processing considerations related to burden on working memory.

  10. 宜丽客 Scope Node

    Institute of Scientific and Technical Information of China (English)

    老未

    2011-01-01

    话说美编卡卡入手了宜丽客(ELECOM)的握笔型镭射鼠Scope Node之后(见2010年最后一期的Gadget),对那玩意可谓是爱不释手,老朱屡次欲把她的爱鼠借来给各位童鞋做个试用报告,均遭到了卡卡无情的拒绝。终于有一天,老朱趁着卡卡吃饱了盖浇饭、趴在桌子上午睡的时候,才偷偷地把Scope Node“借”过来折腾了一番,至此Scope Node之谜才大白于天下。

  11. Synthesis and characterization of new 2-amino-4-(substituted phenyl-6-(7’’-methoxy, 3’’,4’’-dihydro, 2’’,2’’-dimethyl-2hbenzopyran pyrimidines and their bio evaluation

    Directory of Open Access Journals (Sweden)

    Murthy Y.L.N.

    2012-01-01

    Full Text Available A series of eight novel 2-amino-4-(substituted phenyl-6-(7"- methoxy, 3",4"-dihydro, 2",2"-dimethyl-2H-benzopyran pyrimidines were designed and synthesized by utilizing benzene-1,3-diol as starting material. The structures of the isolated products (6a-h were established through 1HNMR, 13C-NMR, and FT-IR spectroscopic techniques and elemental analysis. The synthesized compounds were utilized for screening antimicrobial properties against gram positive (Bacillus pumilus, Bacillus subtilis, Streptococcus faecalis, gram negative bacteria (Enterococcus faecalis, Escheria coli, Proteus vulgaris and fungi (Pencillian expasom, Aspergillus niger, Candida albicans using Ampicillin and Ketoconazole. Most of the compounds showed moderate to high antibacterial and antifungal activities against studied strains with inhibition zones between 8 and 30 mm.

  12. Scope management in web application projects

    Directory of Open Access Journals (Sweden)

    Cristina Coelho de Abreu Pinna

    2008-07-01

    Full Text Available Software projects are subjected to certain risks and uncertainties, especially those that include Web applications, due to the fact that market competition aims to have electronic and virtual services available in a shorter and shorter period of time (also known as “Internet timing”. Another critical factor relates to the focus to be adopted into the management of Web application projects – should technology or business process be emphasized? This fact produces some difficulties in the acceptance of the software by the customer. This problem could be minimized by appropriate management of the project scope from its earliest phases (conception and planning. The article will present an approach that can be utilized on the management of Web applications projects for the minimization of uncertainties and risks when defining scope. A comparative and critical analysis will be carried out among several instruments and techniques that can be utilized on the definition of scope and priorities such as: QFD, Business Process Modeling and Partitioning. Key-words: Project Management, Scope Management, Web applications, QFD.

  13. 20 CFR 411.100 - Scope.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Scope. 411.100 Section 411.100 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Introduction § 411... managers to assist us in the administration of the Ticket to Work program. (e) Subpart E...

  14. 45 CFR 400.40 - Scope.

    Science.gov (United States)

    2010-10-01

    ... Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Immigration Status and Identification of Refugees § 400.40 Scope. This subpart sets forth requirements concerning the immigration...

  15. 76 FR 73596 - Notice of Scope Rulings

    Science.gov (United States)

    2011-11-29

    ... antidumping duty and countervailing duty orders; January 11, 2011. A-570-937/C-570-938/A-122-853: Citric Acid... the antidumping duty order; requested March 4, 2011. A-570-937/C-570-938: Citric Acid and Certain... blends of citric acid and blends of citrate salts are within the scope of the antidumping duty...

  16. 77 FR 9893 - Notice of Scope Rulings

    Science.gov (United States)

    2012-02-21

    ... 24, 2011. A-570-937/C-570-938: Citric Acid and Certain Citrate Salts from the People's Republic of... portion of GCG's ``blended'' citric acid is within the scope of the antidumping duty and countervailing duty orders, and is dutiable according to the amount of citric acid from the PRC that it contains;...

  17. 75 FR 79339 - Notice of Scope Rulings

    Science.gov (United States)

    2010-12-20

    ... future lists after the close of the next calendar quarter. FOR FURTHER INFORMATION CONTACT: Julia Hancock... Rulings, 75 FR 52311 (August 25, 2010). This current notice covers all scope rulings and anticircumvention...; May 12, 2010. A-570-941/C-570-942: Kitchen Appliance Shelving and Racks From the People's Republic...

  18. 42 CFR 409.2 - Scope.

    Science.gov (United States)

    2010-10-01

    ... FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM HOSPITAL INSURANCE BENEFITS Hospital Insurance Benefits: General Provisions § 409.2 Scope. Subparts A through G of this part describe the benefits available under Medicare Part A and set forth the limitations on...

  19. 29 CFR 1450.19 - Scope.

    Science.gov (United States)

    2010-07-01

    ... prohibited by another statute (e.g., travel advances in 5 U.S.C. 5705 and employee training expenses in 5 U.S... STATES Salary Offset § 1450.19 Scope. (a) Coverage. This subpart applies to agencies and employees as... by offset, except where the employee consents to the recovery, from the current pay account of...

  20. 21 CFR 26.3 - Scope.

    Science.gov (United States)

    2010-04-01

    ... PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS, AND CERTAIN... Provisions for Pharmaceutical Good Manufacturing Practices § 26.3 Scope. (a) The provisions of this subpart... inspections and the good manufacturing practices (GMP's) requirements. (c) Appendix B of this subpart...

  1. 34 CFR 686.30 - Scope.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Scope. 686.30 Section 686.30 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER EDUCATION ASSISTANCE FOR COLLEGE AND HIGHER EDUCATION (TEACH) GRANT...

  2. Interdisciplinary Doctoral Research Supervision: A Scoping Review

    Science.gov (United States)

    Vanstone, Meredith; Hibbert, Kathy; Kinsella, Elizabeth Anne; McKenzie, Pam; Pitman, Allan; Lingard, Lorelei

    2013-01-01

    This scoping literature review examines the topic of interdisciplinary doctoral research supervision. Interdisciplinary doctoral research programs are expanding in response to encouragement from funding agencies and enthusiasm from faculty and students. In an acknowledgement that the search for creative and innovative solutions to complex problems…

  3. 29 CFR 18.101 - Scope.

    Science.gov (United States)

    2010-07-01

    ... ADMINISTRATIVE LAW JUDGES Rules of Evidence § 18.101 Scope. These rules govern formal adversarial adjudications... rules as the judge, means an Administrative Law Judge, an agency head, or other officer who presides at the reception of evidence at a hearing in such an adjudication....

  4. 14 CFR 1214.800 - Scope.

    Science.gov (United States)

    2010-01-01

    ... Services § 1214.800 Scope. This subpart 1214.8 establishes the special reimbursement policy for Spacelab services provided to Space Transportation System (STS) customers governed by the provisions of subpart 1214... . (d) Complete-pallet flight . (e) Shared-element flight ....

  5. 32 CFR 775.8 - Scoping.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Scoping. 775.8 Section 775.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES PROCEDURES FOR IMPLEMENTING THE... to be addressed and to identify the significant issues to be analyzed in depth related to...

  6. 32 CFR 319.3 - Scope.

    Science.gov (United States)

    2010-07-01

    ... INTELLIGENCE AGENCY PRIVACY PROGRAM § 319.3 Scope. (a) Any individual who is a citizen of the United States or... Defense Intelligence Agency. (b) These rules apply to those systems of records: (1) Maintained by the Defense Intelligence Agency; (2) For which the Defense Intelligence Agency prescribes the content...

  7. Every document has a geographical scope

    NARCIS (Netherlands)

    Andogah, G.; Bouma, G.; Nerbonne, J.

    2012-01-01

    It is a useful premise to assume that every document in a collection and every query issued to an information retrieval (IR) system are geography-dependent. If one can determine what area an article is about (i.e., its geographical scope), this information can be used to improve the accuracy with wh

  8. 14 CFR 77.21 - Scope.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Scope. 77.21 Section 77.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE OBJECTS... Alaska or Pacific Airman's Guide and Chart Supplement; or (2) A planned or proposed airport or an...

  9. 14 CFR 77.11 - Scope.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Scope. 77.11 Section 77.11 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE OBJECTS... supplemental notices 48 hours before the start and upon the completion of certain construction or...

  10. On the Scope of Egalitarian Justice

    Directory of Open Access Journals (Sweden)

    Joseph Heath

    2006-05-01

    Full Text Available It is not clear whether the social contract is supposed to merely supplement the unequal gains that individuals are able to make through the exercise of their natural endowments with a set of equal gains secured through social cooperation, or whether the social contract must also compensate individuals for the effects of these natural inequalities, so that they literally become all equal. The issue concerns, in effect, whether natural inequality falls within the scope of egalitarian justice. I think it is fair to say that the majority of egalitarians assume that the principle of equality imposes an obligation to redress natural inequality. Yet there is no consensus on this issue. David Gauthier has made the rejection of the principle of redress a central component of his project. It has often escaped notice that John Rawls also rejects the principle of redress. Thus it is not just anti-egalitarians who reject the principle of redress. There is a current of egalitarian thought– which we might call, for lack of a better term, narrow-scope egalitarianism – which also rejects this principle. In this paper, I would like to show that there is considerable wisdom in the narrow-scope egalitarian position. Many of the problems that lead theorists to reject egalitarianism in its entirety are a consequence, not of the principle of equality per se, but rather of the commitment to redress natural inequality. The narrow-scope view avoids all of these difficulties.

  11. 16 CFR 1501.2 - Scope.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Scope. 1501.2 Section 1501.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS METHOD FOR... older. In addition, it does not apply to all articles to which children under 3 years of age might...

  12. 40 CFR 263.10 - Scope.

    Science.gov (United States)

    2010-07-01

    ... Scope. (d) A transporter of hazardous waste subject to the Federal manifesting requirements of 40 CFR... hazardous waste within the United States if the transportation requires a manifest under 40 CFR part 262... water, a transporter who meets all applicable requirements of 49 CFR parts 171 through 179 and...

  13. 48 CFR 970.4400 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope. 970.4400 Section 970.4400 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Management and Operating Contractor Purchasing 970.4400...

  14. 42 CFR 415.50 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 415.50 Section 415.50 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM... IN CERTAIN SETTINGS Fiscal Intermediary Payments to Providers for Physician Services § 415.50...

  15. 48 CFR 970.0808-00 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope. 970.0808-00 Section 970.0808-00 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Required sources of supplies and services 970.0808-00...

  16. 29 CFR 1926.750 - Scope.

    Science.gov (United States)

    2010-07-01

    ...) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Steel Erection § 1926.750 Scope. (a) This subpart sets... involved in the construction, alteration, and/or repair of single and multi-story buildings, bridges, and... steel erection may occur include but are not limited to the following: Single and multi-story...

  17. 34 CFR 603.20 - Scope.

    Science.gov (United States)

    2010-07-01

    ... authorities as to the quality of public postsecondary vocational education in their respective States for the... statutory standards as to the quality of public postsecondary vocational education to be undertaken by... 34 Education 3 2010-07-01 2010-07-01 false Scope. 603.20 Section 603.20 Education Regulations...

  18. 42 CFR 456.700 - Scope.

    Science.gov (United States)

    2010-10-01

    ... ASSISTANCE PROGRAMS UTILIZATION CONTROL Drug Use Review (DUR) Program and Electronic Claims Management System... 42 Public Health 4 2010-10-01 2010-10-01 false Scope. 456.700 Section 456.700 Public Health... outpatient DUR program that includes prospective drug review, retrospective drug use review, and...

  19. 44 CFR 206.343 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope. 206.343 Section 206.343 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND... orientation which is unrelated to development is not subject to the requirements of these regulations....

  20. 14 CFR 171.21 - Scope.

    Science.gov (United States)

    2010-01-01

    ... FACILITIES NON-FEDERAL NAVIGATION FACILITIES Nondirectional Radio Beacon Facilities § 171.21 Scope. (a) This... radio beacon facilities that are to be involved in the approval of instrument flight rules and air traffic control procedures related to those facilities. (b) A nondirectional radio beacon (“H”...

  1. 47 CFR 15.601 - Scope.

    Science.gov (United States)

    2010-10-01

    ... FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Access Broadband Over Power Line (Access BPL) § 15.601 Scope. This subpart sets out the regulations for Access Broadband over Power Line (Access BPL) devices operating in the 1.705-80 MHz band over medium or low voltage lines....

  2. 7 CFR 622.2 - Scope.

    Science.gov (United States)

    2010-01-01

    ... proper utilization of land, flood prevention, agricultural water management including irrigation and... 7 Agriculture 6 2010-01-01 2010-01-01 false Scope. 622.2 Section 622.2 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT...

  3. 7 CFR 701.3 - Scope.

    Science.gov (United States)

    2010-01-01

    ... participants on eligible land for certain practices, to rehabilitate farmland damaged by floods, hurricanes... 7 Agriculture 7 2010-01-01 2010-01-01 false Scope. 701.3 Section 701.3 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  4. 40 CFR 300.3 - Scope.

    Science.gov (United States)

    2010-07-01

    ... Introduction § 300.3 Scope. (a) The NCP applies to and is in effect for: (1) Discharges of oil into or on the... States. (b) The NCP provides for efficient, coordinated, and effective response to discharges of oil and... implementing the NCP, consideration shall be given to international assistance plans and agreements,...

  5. 47 CFR 73.401 - Scope.

    Science.gov (United States)

    2010-10-01

    ... FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Digital Audio Broadcasting § 73.401 Scope. This subpart contains those rules which apply exclusively to the digital audio broadcasting (DAB) service, and are in addition to those rules in Subparts A, B, C, G and...

  6. 47 CFR 68.2 - Scope.

    Science.gov (United States)

    2010-10-01

    ... EQUIPMENT TO THE TELEPHONE NETWORK General § 68.2 Scope. (a) Except as provided in paragraphs (b) and (c) of... public switched telephone network for use in conjunction with all services other than party line services... telephone company provided communications network without compliance with this part, provided that...

  7. 20 CFR 902.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ...' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES RULES REGARDING AVAILABILITY OF INFORMATION § 902.1 Scope. This part is issued by the Joint Board for the Enrollment of Actuaries (the “Joint Board... may obtain information, make submittals or requests, or obtain decisions....

  8. 16 CFR 1101.2. - Scope.

    Science.gov (United States)

    2010-01-01

    ... Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Background § 1101.2. Scope. Section 6(b) and these... Law 110-278, 122 Stat. 2602 (July 17, 2008)....

  9. 32 CFR 552.212 - Scope.

    Science.gov (United States)

    2010-07-01

    ... Installation of Aberdeen Proving Ground, Maryland § 552.212 Scope. (a) The provisions of this subpart apply to all elements of U.S. Army Garrison, Aberdeen Proving Ground (USAGAPG), and the supported organizations and activities on the Aberdeen and Edgewood Areas of Aberdeen Proving Ground. (b) The provisions...

  10. 22 CFR 8.3 - Scope.

    Science.gov (United States)

    2010-04-01

    ... personnel); (4) Has an organizational structure (e.g., officers) and a staff. (c) Where a group provides... DEPARTMENT OF STATE GENERAL ADVISORY COMMITTEE MANAGEMENT § 8.3 Scope. (a) The Federal Advisory Committee Act... Office of Management and Budget, may establish a group which shall be known as an advisory committee...

  11. 45 CFR 5.3 - Scope.

    Science.gov (United States)

    2010-10-01

    ... § 5.3 Scope. These rules apply to all components of the Department. Some units may establish additional rules because of unique program requirements, but such rules must be consistent with these rules and must have the concurrence of the Assistant Secretary for Public Affairs. Existing...

  12. Examining Young Students' Problem Scoping in Engineering Design

    Science.gov (United States)

    Watkins, Jessica; Spencer, Kathleen; Hammer, David

    2014-01-01

    Problem scoping--determining the nature and boundaries of a problem--is an essential aspect of the engineering design process. Some studies from engineering education suggest that beginning students tend to skip problem scoping or oversimplify a problem. However, the ways these studies often characterize students' problem scoping often do not…

  13. 34 CFR 690.1 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Scope and purpose. 690.1 Section 690.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PELL GRANT PROGRAM Scope, Purpose and General Definitions § 690.1 Scope...

  14. SCOPE : an intelligent maintenance system for supporting crew operations

    NARCIS (Netherlands)

    Bos, A.; Breebaart, L.; Neerincx, M.A.; Wolff, M.

    2004-01-01

    This paper describes an intelligent maintenance system for Supporting Crew OPErations (SCOPE). SCOPE supports the astronauts onboard the ISS and helps them to maximize the availability of complex payload systems. SCOPE detects system failures, guides the isolation of the root causes of failure, and

  15. 29 CFR 2.10 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Scope and purpose. 2.10 Section 2.10 Labor Office of the Secretary of Labor GENERAL REGULATIONS Audiovisual Coverage of Administrative Hearings § 2.10 Scope and purpose. This subpart defines the scope of audiovisual coverage of departmental administrative...

  16. 45 CFR 703.3 - Scope of subject matter.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which...

  17. Latin American forensic pathology: scope and needs

    Directory of Open Access Journals (Sweden)

    Gabriel M. Fonseca

    2012-10-01

    Full Text Available Pathology pertains to the study of a disease; from ancient times it has sought to explain the cause of death through postmortem examination. The advancement of science and technology has led to a greater definition of roles and has favored its development through different subspecialties among which we stands out forensic pathology. This discipline has its own characteristics, scope, case series, procedures and terminology. Likewise, although forensic pathology does not differ substantially from clinical pathology, significant differences can be found between the Anglo American approach and the Latin American approach. Beyond semantics of these alleged differences, the article reviews the concepts involved and discusses the scope and requirements needed to qualify experts, in the understanding that globalizing criteria should establish new paradigms and define the specific roles of the specialty.

  18. Reduced attentional scope in cocaine polydrug users.

    Directory of Open Access Journals (Sweden)

    Lorenza S Colzato

    Full Text Available Cocaine is Europe's second preferred recreational drug after cannabis but very little is known about possible cognitive impairments in the upcoming type of recreational cocaine user (monthly consumption. We asked whether recreational use of cocaine impacts early attentional selection processes. Cocaine-free polydrug controls (n = 18 and cocaine polydrug users (n = 18 were matched on sex, age, alcohol consumption, and IQ (using the Raven's progressive matrices, and were tested by using the Global-Local task to measure the scope of attention. Cocaine polydrug users attended significantly more to local aspects of attended events, which fits with the idea that a reduced scope of attention may be associated with the perpetuation of the use of the drug.

  19. Revising the Complex Economics of Patent Scope

    DEFF Research Database (Denmark)

    Howells, John

    Merges and Nelson claim to have provided an empirically grounded argument that pioneer patents of 'broad' scope are used to block technological development. It is widely understood in both law and economics that they have, as they claim, faulted Kitch's 'prospect theory' of patents, a theory...... that a function of patents is to enable the coordinated development of novel technical ideas. This article is a critical review of Merges and Nelson's historical empirical evidence. I find that, first, 'broad' scope is only implicated in one of the examples cited by Merges and Nelson as supportive evidence...... - the Wright brothers' warped-wing patent; second, that strict development block, defined as the prevention, or retardation of the development of technology understood to be capable of useful development, was not illustrated by any of their examples. Therefore I conclude that their general thesis...

  20. How the Cloud Stretches the SOA Scope

    Directory of Open Access Journals (Sweden)

    Lakshmanan G

    2012-09-01

    Full Text Available In this article, we will describe how the enterprise serviceoriented-architecture (SOA scope is stretched with the advent of cloud computing. With the help of the case study of a fictitious global retailer, we will demonstrate the process for identifying cloud scenarios. Also, we will come across an emerging breed of distributed applications—both on-premise and in the Cloud—and discuss the integration considerations for building them.

  1. Superposition and Entanglement from Quantum Scope

    OpenAIRE

    Wang, Dong-sheng

    2011-01-01

    The abstract framework of quantum mechanics (QM) causes the well-known weirdness, which leads to the field of foundation of QM. We constructed the new concept, i.e., scope, to lay the foundation of quantum coherence and openness, also the principles of superposition and entanglement. We studied analytically and quantitatively the quantum correlations and information, also we discussed the physical essence of the existed entanglement measures. We compared with several other approaches to the f...

  2. Industrial Scope of Agglomeration Economies in Brazil

    OpenAIRE

    Ana Maria Bonomi Barufi; Eduardo A. Haddad, Peter Nijkamp

    2015-01-01

    The tendency towards urbanization in the emerging world accompanied by the constant pursuit for higher productivity prompts an urge for studies aiming at understanding agglomeration economies. In the context of Brazil, a country with extremely high regional disparities, exploring this issue is important not only for private stakeholders, but also for public policy practitioners. In the framework of static agglomeration effects, we investigate the industrial scope of agglomeration economies in...

  3. 40 CFR 81.300 - Scope.

    Science.gov (United States)

    2010-07-01

    ... CFR 51.100 and § 81.1 (i) Early Action Compact. The term “early action compact” (“compact”) means an... Air Act (42 U.S.C. 7401 et seq.) codified at 40 CFR 50.10. (2) What Are Early Action Compact Areas... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Scope. 81.300 Section...

  4. Reducing ICT project failure with scope management

    OpenAIRE

    Acquah, Ato

    2011-01-01

    Over the years, Information Communications and Technology projects have had a high rate of failure according to previous research findings. The aim of this thesis is to investigate the various factors causing project failure and to show how the problem can be eliminated or reduced by effectively managing the scope of projects. The research approach used was a qualitative method with an empirical investigation. The thesis was divided into two parts, the Theoretical part and Empirical p...

  5. Detours in Scope-Based Route Planning

    CERN Document Server

    Hliněný, Petr

    2012-01-01

    We study a dynamic scenario of the static route planning problem in road networks. Particularly, we put accent on the most practical dynamic case - increased edge weights (up to infinity). We show how to enhance the scope-based route planning approach presented at ESA'11 to intuitively by-pass closures by detours. Three variants of a detour "admissibility" are presented - from a simple one with straightforward implementation through its enhanced version to a full and very complex variant variant which always returns an optimal detour.

  6. Home care safety markers: a scoping review.

    Science.gov (United States)

    Macdonald, Marilyn; Lang, Ariella; Storch, Jan; Stevenson, Lynn; Donaldson, Susan; Barber, Tanya; Iaboni, Kristine

    2013-01-01

    Safety in home care is a new research frontier, and one in which demand for services continues to rise. A scoping review of the home care literature on chronic obstructive pulmonary disease and congestive heart failure was thus completed to identify safety markers that could serve to develop our understanding of safety in this sector. Results generated seven safety markers: (a) Home alone; (b) A fixed agenda in a foreign language; (c) Strangers in the home; (d) The butcher, the baker, the candlestick maker; (e) Medication mania; (f) Out of pocket: The cost of caring at home; and (g) My health for yours: Declining caregiver health. PMID:23679662

  7. Objectives, scope and programme of work

    International Nuclear Information System (INIS)

    The objectives and scope for Working Group 1 were: (1) to estimate needs for nuclear energy and correlated needs for uranium and heavy water according to different fuel cycle strategies; (2) to review uranium availability; (3) to review heavy water availability; (4) to review thorium availability; (5) to consider special needs of developing countries. Sub-Groups were formed to carry out specific parts of the evaluation as follows: Sub-Group A: Nuclear Growth and Demand. Sub-Group B: Nuclear Fuel Resources. Sub-Group C: Technical and Political Aspects of Uranium and Thorium Exploration and Production. Sub-Group D: Heavy Water Availability

  8. What We Mean by Scope and Methods: A Survey of Undergraduate Scope and Methods Courses

    Science.gov (United States)

    Turner, Charles C.; Thies, Cameron G.

    2009-01-01

    Self-reflective political scientists have extensively reviewed the history of the discipline and argued over its future, but to date there has been little effort to systematically survey undergraduate scope and methods courses (for an exception see Thies and Hogan 2005). This lack of data leaves the discipline unable to assess how much we are…

  9. Hardware Support for Safety-critical Java Scope Checks

    DEFF Research Database (Denmark)

    Rios Rivas, Juan Ricardo; Schoeberl, Martin

    2012-01-01

    Memory management in Safety-Critical Java (SCJ) is based on time bounded, non garbage collected scoped memory regions used to store temporary objects. Scoped memory regions may have different life times during the execution of a program and hence, to avoid leaving dangling pointers, it is necessary...... in terms of execution time for applications where cross-scope references are frequent. Our proposal was implemented and tested on the Java Optimized Processor (JOP)....

  10. EarthScope Education and Outreach: Accomplishments and Emerging Opportunities

    Science.gov (United States)

    Robinson, S.; Ellins, K. K.; Semken, S. C.; Arrowsmith, R.

    2014-12-01

    EarthScope's Education and Outreach (E&O) program aims to increase public awareness of Earth science and enhance geoscience education at the K-12 and college level. The program is distinctive among major geoscience programs in two ways. First, planning for education and public engagement occurred in tandem with planning for the science mission. Second, the NSF EarthScope program includes funding support for education and outreach. In this presentation, we highlight key examples of the program's accomplishments and identify emerging E&O opportunities. E&O efforts have been collaboratively led by the EarthScope National Office (ESNO), IRIS, UNAVCO, the EarthScope Education and Outreach Subcommittee (EEOSC) and PI-driven EarthScope projects. Efforts by the EEOSC, guided by an EarthScope Education and Outreach Implementation Plan that is periodically updated, focus EarthScope E&O. EarthScope demonstrated early success in engaging undergraduate students (and teachers) in its mission through their involvement in siting USArray across the contiguous U.S. Funded E&O programs such as TOTLE, Illinois EarthScope, CEETEP (for K-12), InTeGrate and GETSI (for undergraduates) foster use of freely available EarthScope data and research findings. The Next Generation Science Standards, which stress science and engineering practices, offer an opportunity for alignment with existing EarthScope K-12 educational resources, and the EEOSC recommends focusing efforts on this task. The EEOSC recognizes the rapidly growing use of mobile smart devices by the public and in formal classrooms, which bring new opportunities to connect with the public and students. This will capitalize on EarthScope's already prominent social media presence, an effort that developed to accomplish one of the primary goals of the EarthScope E&O Implementation Plan to "Create a high-profile public identity for EarthScope" and to "Promote science literacy and understanding of EarthScope among all audiences through

  11. Prioritising Project Scope Definition Elements in Public Building Projects

    Directory of Open Access Journals (Sweden)

    Mohammed K Fageha

    2014-09-01

    Full Text Available A complete definition of the scope of a project upfront during early stages ensures smooth and successful implementation during the project execution. This research identifies and prioritises project scope definition elements for public buildings in Saudi Arabia. Elements that could significantly contribute to complete project scope definition package at pre-project planning stage are identified and their interrelationship determined and prioritised. Using the Project Definition Rating Index (PDRI as a basis, the study uses analytical network process (ANP technique based on data obtained from project managers who have been involved in public sector projects in Saudi Arabia. Data collection and analysis was conducted in three steps. The first step involved identification of scope definition elements while the second involved an investigation into interrelationships among the elements. In the third step, ANP was used to determine the weight of the elements’ importance in terms of contribution to project scope definition completeness. Finally, Pareto analysis was used to prioritise and assess the distribution pattern of the elements. The outcome from this research is the prioritisation of project scope definition elements for public building projects in Saudi Arabia. The prioritised list developed indicates the importance of project scope definition elements. It should help project management teams identify elements to consider when evaluating project scope definition for completeness at the pre-project planning stage. Keywords: Project scope definition, pre-project planning, prioritising, public building projects, Saudi Arabia, Analytical Network Process (ANP

  12. CMS Phase II Upgrade Scope Document

    CERN Document Server

    Butler, J; Klute, M; Mans, J; Silvestris, L; on behalf of the CMS, Collaboration; CERN. Geneva. The LHC experiments Committee; LHCC

    2015-01-01

    The High-Luminosity LHC (HL-LHC) has been identified as the highest priority program in High Energy Physics by both the European Strategy Group and the US Particle Physics Project Prioritization Panel. To fulfil the full potential of this program, which includes the study of the nature of the Higgs boson, the investigation of the properties of any newly discovered particles in the upcoming LHC runs, and the extension of the mass reach for further discoveries, an integrated luminosity of 3000 fb-1 will have to be accumulated by the end of the program. In preparation for operation at the HL-LHC , CMS has documented the necessary upgrades and their expected costs in a Technical Proposal submitted to the CERN LHC Committee (LHCC) in mid-2015. The material presented in the current “Scope Document” provides additional information to assist the LHCC and the CERN Resource Review Board (RRB) in their review of the CMS upgrade. The document commences with a summary of the process followed to develop the scope of t...

  13. Optical fiber scope for inspecting fuel assembly

    International Nuclear Information System (INIS)

    Since a fiber scope has only one objective section, it has to observe a plurality of places successively. Then, if the time for the observation is long, the objective section is deteriorated by radiation rays, which causes a problem of interrupting the observation and increasing operator's radiation dose. In view of the above, one or two light guides are combined with an image guide to form one objective section, and a plurality of them are formed in parallel and gathered as a comb-like shape. A prism is put into a window of the objective section and resins are filled or a glass cover is attached, to make the objective section smooth and flat. Compared with the case of using only one objective section, it is no more necessary for successive observation, and objection can be conducted at one time. For example, if a fiber scope having nine objective sections is used for observing 8 x 8 arrangement fuel assembly, the observation time is shortened to 1/9. Since the prism, the glass cover, and the resins are used for making the window flat, cruds deposited between the optical fiber and a reflection mirror are easily removed, to obtain clear images. (N.H.)

  14. 39 CFR 3030.2 - Scope and nature of complaints.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Scope and nature of complaints. 3030.2 Section 3030.2 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS General § 3030.2 Scope and nature of complaints. Any interested person (including a duly appointed officer of...

  15. 27 CFR 479.81 - Scope of tax.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Scope of tax. 479.81... OTHER FIREARMS Transfer Tax § 479.81 Scope of tax. Except as otherwise provided in this part, each transfer of a firearm in the United States is subject to a tax to be represented by an adhesive stamp...

  16. 40 CFR 260.1 - Purpose, scope, and applicability.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Purpose, scope, and applicability. 260.1 Section 260.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) HAZARDOUS WASTE MANAGEMENT SYSTEM: GENERAL General § 260.1 Purpose, scope, and applicability....

  17. 42 CFR 410.1 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... SUPPLEMENTARY MEDICAL INSURANCE (SMI) BENEFITS General Provisions § 410.1 Basis and scope. (a) Statutory basis...—Scope of benefits furnished under the Medicare Part B supplementary medical insurance (SMI) program. (2) Section 1833 through 1835 and 1862—Amounts of payment for SMI services, the conditions for payment,...

  18. 21 CFR 1230.2 - Scope of the act.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope of the act. 1230.2 Section 1230.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS... CAUSTIC POISON ACT General Provisions § 1230.2 Scope of the act. The provisions of the act apply to...

  19. 21 CFR 1210.2 - Scope of act.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope of act. 1210.2 Section 1210.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER... MILK ACT General Provisions § 1210.2 Scope of act. The provisions of the act apply to all milk...

  20. 10 CFR 709.10 - Scope of a counterintelligence evaluation.

    Science.gov (United States)

    2010-01-01

    ... authorities. As provided in § 709.3(b), DOE also may require a CI-scope polygraph examination. As provided for in § 709.3(c), a CI evaluation, if conducted on a random basis, will include a CI-scope...

  1. 29 CFR 1606.2 - Scope of title VII protection.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Scope of title VII protection. 1606.2 Section 1606.2 Labor... BECAUSE OF NATIONAL ORIGIN § 1606.2 Scope of title VII protection. Title VII of the Civil Rights Act of..., religion, sex or national origin. The title VII principles of disparate treatment and adverse...

  2. 45 CFR 302.0 - Scope of this part.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Scope of this part. 302.0 Section 302.0 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES STATE PLAN REQUIREMENTS § 302.0 Scope of this...

  3. 41 CFR 105-1.000-50 - Scope of part.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of part. 105-1.000-50 Section 105-1.000-50 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION § 105-1.000-50 Scope of...

  4. 42 CFR 73.2 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Purpose and scope. 73.2 Section 73.2 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION, LICENSING SELECT AGENTS AND TOXINS § 73.2 Purpose and scope. This part implements the provisions of the Public...

  5. 10 CFR 431.191 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 431.191 Section 431.191 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Distribution Transformers § 431.191 Purpose and scope. This subpart contains energy conservation requirements for distribution...

  6. 10 CFR 63.201 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Purpose and scope. 63.201 Section 63.201 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Preclosure Public Health and Environmental Standards § 63.201 Purpose and scope....

  7. 10 CFR 63.301 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Purpose and scope. 63.301 Section 63.301 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards § 63.301 Purpose and scope....

  8. 7 CFR 1773.38 - Scope of engagement.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Scope of engagement. 1773.38 Section 1773.38 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF... § 1773.38 Scope of engagement. (a) RUS requires that the audit procedures set forth in §§ 1773.39...

  9. 41 CFR 101-28.000 - Scope of part.

    Science.gov (United States)

    2010-07-01

    ... Scope of part. This part prescribes policy and procedures for the economical and efficient management of... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of part. 101-28.000 Section 101-28.000 Public Contracts and Property Management Federal Property Management Regulations...

  10. Literacy Teaching Aids from High/Scope Educational Research Foundation

    Science.gov (United States)

    Science Activities: Classroom Projects and Curriculum Ideas, 2005

    2005-01-01

    High/Scope's approach to education is a blend of Jean Piaget's constructivist theory of child development and the best of traditional teacher experience. The High/Scope approach is about helping students gain knowledge and skills in important content areas, such as language and literacy, initiative and social relations, movement, music, and…

  11. 7 CFR 3406.16 - Scope of a research proposal.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Scope of a research proposal. 3406.16 Section 3406.16 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION... Preparation of a Research Proposal § 3406.16 Scope of a research proposal. The research component of...

  12. 48 CFR 4.800 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Scope of subpart. 4.800 Section 4.800 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL ADMINISTRATIVE MATTERS Government Contract Files 4.800 Scope of subpart. This subpart prescribes requirements...

  13. 30 CFR 775.1 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Scope and purpose. 775.1 Section 775.1 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SURFACE COAL... ADMINISTRATIVE AND JUDICIAL REVIEW OF DECISIONS § 775.1 Scope and purpose. This part provides requirements...

  14. 32 CFR 775.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... Quality Regulations for Implementing the Procedural Provisions of NEPA, 40 CFR 1500-1508, and the... 32 National Defense 5 2010-07-01 2010-07-01 false Purpose and scope. 775.1 Section 775.1 National... IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT § 775.1 Purpose and scope. (a) To implement the...

  15. 31 CFR 203.9 - Scope of the subpart.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Scope of the subpart. 203.9 Section 203.9 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... LOAN PROGRAM Electronic Federal Tax Payments § 203.9 Scope of the subpart. This subpart prescribes...

  16. 32 CFR 235.2 - Applicability and scope.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Applicability and scope. 235.2 Section 235.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SALE OR RENTAL OF SEXUALLY EXPLICIT MATERIAL ON DOD PROPERTY § 235.2 Applicability and scope....

  17. 42 CFR 405.2411 - Scope of benefits.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Scope of benefits. 405.2411 Section 405.2411 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM... Center Services § 405.2411 Scope of benefits. (a) Rural health clinic services reimbursable under...

  18. 47 CFR 80.1187 - Scope of communication.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Scope of communication. 80.1187 Section 80.1187... MARITIME SERVICES Voluntary Radio Installations Mobile-Satellite Stations § 80.1187 Scope of communication. Ship earth stations must be used for telecommunications related to the business or operation of...

  19. Internationalization of the Counseling Profession: Meaning, Scope and Concerns

    Science.gov (United States)

    Ng, Kok-Mun; Noonan, Brigid M.

    2012-01-01

    The present study sought to clarify the meaning and delineate the scope of internationalization of the counseling profession. Using a qualitative approach, the study recruited a panel of eight experts to help generate a consensus statement on the meaning of internationalization to the counseling profession and to delineate a five-theme scope of…

  20. 10 CFR 820.70 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and scope. 820.70 Section 820.70 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES Criminal Penalties § 820.70 Purpose and scope... Requirements and the referral of such violations to the Department of Justice....

  1. 12 CFR 363.1 - Scope and definitions.

    Science.gov (United States)

    2010-01-01

    ... company means an insured depository institution or other company that does not meet the definition of a... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Scope and definitions. 363.1 Section 363.1... ANNUAL INDEPENDENT AUDITS AND REPORTING REQUIREMENTS § 363.1 Scope and definitions. (a)...

  2. 29 CFR 500.70 - Scope of worker protections.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Scope of worker protections. 500.70 Section 500.70 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Worker Protections General § 500.70 Scope of worker protections....

  3. 5 CFR 890.1001 - Scope and purpose.

    Science.gov (United States)

    2010-01-01

    ....1001 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... Providers General Provisions and Definitions § 890.1001 Scope and purpose. (a) Scope. This subpart implements 5 U.S.C. 8902a, as amended by Public Law 105-266 (October 19, 1998). It establishes a system...

  4. 48 CFR 504.500 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATIVE MATTERS Electronic Commerce in Contracting 504.500 Scope of subpart. This subpart provides policy and procedure for use of GSA's Electronic Posting System (EPS). ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Scope of subpart....

  5. The AuScope Geodetic VLBI Array

    CERN Document Server

    Lovell, J E J; Reid, P B; McCulloch, P M; Baynes, B E; Dickey, J M; Shabala, S S; Watson, C S; Titov, O; Ruddick, R; Twilley, R; Reynolds, C; Tingay, S J; Shield, P; Adada, R; Ellingsen, S P; Morgan, J S; Bignall, H E; 10.1007/s00190-013-0626-3

    2013-01-01

    The AuScope geodetic Very Long Baseline Interferometry array consists of three new 12 m radio telescopes and a correlation facility in Australia. The telescopes at Hobart (Tasmania), Katherine (Northern Territory) and Yarragadee (Western Australia) are co-located with other space geodetic techniques including Global Navigation Satellite Systems (GNSS) and gravity infrastructure, and in the case of Yarragadee, Satellite Laser Ranging (SLR) and Doppler Orbitography and Radiopositioning Integrated by Satellite (DORIS) facilities. The correlation facility is based in Perth (Western Australia). This new facility will make significant contributions to improving the densification of the International Celestial Reference Frame in the Southern Hemisphere, and subsequently enhance the International Terrestrial Reference Frame through the ability to detect and mitigate systematic error. This, combined with the simultaneous densification of the GNSS network across Australia will enable the improved measurement of intrapl...

  6. REBUILD AMERICA PROGRAM SCOPE OF WORK

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey Brown; Bruce Exstrum

    2004-12-01

    This report summarizes the activities carried out by Aspen Systems Corporation in support of the Department of Energy's Rebuild America program during the period from October 9, 1999 to October 31, 2004. These activities were in accordance with the Scope of Work contained in a GSA MOBIS schedule task order issued by the National Energy Technology Laboratory. This report includes descriptions of activities and results in the following areas: deployment/delivery model; program and project results; program representative support activities; technical assistance; web site development and operation; business/strategic partners; and training/workshop activities. The report includes conclusions and recommendations. Five source documents are also provided as appendices.

  7. NASA Scope and Subject Category Guide

    Science.gov (United States)

    2011-01-01

    This guide provides a simple, effective tool to assist aerospace information analysts and database builders in the high-level subject classification of technical materials. Each of the 76 subject categories comprising the classification scheme is presented with a description of category scope, a listing of subtopics, cross references, and an indication of particular areas of NASA interest. The guide also includes an index of nearly 3,000 specific research topics cross referenced to the subject categories. The portable document format (PDF) version of the guide contains links in the index from each input subject to its corresponding categories. In addition to subject classification, the guide can serve as an aid to searching databases that use the classification scheme, and is also an excellent selection guide for those involved in the acquisition of aerospace literature. The CD-ROM contains both HTML and PDF versions.

  8. Observational therapeutics: Scope, challenges, and organization

    Directory of Open Access Journals (Sweden)

    Rama Vaidya

    2011-01-01

    Full Text Available The importance of Observational Therapeutics in the progress of medicine has been neglected in the current era of the hierarchal position imparted to Randomized Controlled Trials (RCTs for new drug discovery and practice of evidence-based medicine. There is a need to reflect on the reason for many new drugs being withdrawn during post marketing surveillance. There are several examples in literature where drug-discovery has originated initially from keen clinical and / or laboratory observations. The roots of these discoveries have often been from observations made by practitioners of traditional medicine including Ayurveda. The present article draws attention to the scope and challenges for observational therapeutics. There is an urgent need for the meticulous planning for a systematic organization of developing observational therapeutics, with a full understanding of its strengths and limitations.

  9. Automation scope at Roxboro generating station

    International Nuclear Information System (INIS)

    Many fossil fired power plant have replaced their aging unit control hardware with modern DCS technology. This paper describes a jointly sponsored project by EPRI, Carolina Power and Light Co. (CP and L) and ABB, to implement plant automation functions which would complement DCS technology, and result in improvements in plant operations in terms of heat rate, availability, and operations cost. These will be demonstrated at CP and L's Roxboro Station, a 4 unit coal fired plant with total capacity of nearly 2,477 MW. The scope of this four year project includes installation of a plant-wide information management system, automation of unit testing, implementation of advanced controls, intelligent alarms, operator advisory functions, and a plant-wide simulator, as well as support for plant unit economic dispatch

  10. Scope of algae as third generation biofuels

    Directory of Open Access Journals (Sweden)

    Shuvashish eBehera

    2015-02-01

    Full Text Available An initiative has been taken to develop different solid, liquid and gaseous biofuels as the alternative energy resources. The current research and technology based on the third generation biofuels derived from algal biomass have been considered as the best alternative bioresource that avoids the disadvantages of first and second generation biofuels. Algal biomass have been investigated for the implementation of economic conversion processes producing different biofuels such as biodiesel, bioethanol, biogas, biohydrogen and other valuable co-products. In the present review, the recent findings and advance developments in algal biomass for improved biofuel production. This review discusses about the importance of the algal cell contents, various strategies for product formation through various conversion technologies, and its future scope as an energy security.

  11. EarthScope's Transportable Array in Alaska

    Science.gov (United States)

    Busby, R. W.; Woodward, R.; Hafner, K.

    2013-12-01

    Since 2003, EarthScope has been installing a network of seismometers, known as the Transportable Array-across the continental United States and southern Canada. The station deployments will be completed in the Conterminous US in the fall of 2013. Beginning in October, 2013, and continuing for 5 years, EarthScope's Transportable Array plans to create a grid of seismic sensors in approximately 300 locations In Alaska and Western Canada. The proposed station grid is 85 km, and target locations will supplement or enhance existing seismic stations operating in Alaska. When possible, they will also be co-located with existing GPS stations constructed by the Plate Boundary Observatory. We review the siting plans for stations, the progress towards reconnaissance and permitting, and detail the engineering concept of the stations. In order to be able to determine the required site conditions and descriptions of installation methods to the permitting agencies, the National Science Foundation (NSF) has been supporting exploratory work on seismic station design, sensor emplacement and communication concepts appropriate for the challenging high-latitude environment that is proposed for deployment. IRIS has installed several experimental stations to evaluate different sensor emplacement schemes both in Alaska and the lower-48 U.S. The goal of these tests is to maintain or enhance a station's noise performance while minimizing its footprint and the equipment, materials, and overall expense required for its construction. Motivating this approach are recent developments in posthole broadband seismometer design and the unique conditions for operating in Alaska, where most areas are only accessible by small plane or helicopter, and permafrost underlies much of the region. IRIS has experimented with different portable drills and drilling techniques to create shallow holes (1-5M) in permafrost and rock outcrops. Seasonal changes can affect the performance of seismometers in different

  12. Scoping Review of the Zika Virus Literature.

    Directory of Open Access Journals (Sweden)

    Lisa A Waddell

    Full Text Available The global primary literature on Zika virus (ZIKV (n = 233 studies and reports, up to March 1, 2016 has been compiled using a scoping review methodology to systematically identify and characterise the literature underpinning this broad topic using methods that are documented, updateable and reproducible. Our results indicate that more than half the primary literature on ZIKV has been published since 2011. The articles mainly covered three topic categories: epidemiology of ZIKV (surveillance and outbreak investigations 56.6% (132/233, pathogenesis of ZIKV (case symptoms/ outcomes and diagnosis 38.2% (89/233 and ZIKV studies (molecular characterisation and in vitro evaluation of the virus 18.5% (43/233. There has been little reported in the primary literature on ZIKV vectors (12/233, surveillance for ZIKV (13/233, diagnostic tests (12/233 and transmission (10/233. Three papers reported on ZIKV prevention/control strategies, one investigated knowledge and attitudes of health professionals and two vector mapping studies were reported. The majority of studies used observational study designs, 89.7% (209/233, of which 62/233 were case studies or case series, while fewer (24/233 used experimental study designs. Several knowledge gaps were identified by this review with respect to ZIKV epidemiology, the importance of potential non-human primates and other hosts in the transmission cycle, the burden of disease in humans, and complications related to human infection with ZIKV. Historically there has been little research on ZIKV; however, given its current spread through Australasia and the Americas, research resources are now being allocated to close many of the knowledge gaps identified in this scoping review. Future updates of this project will probably demonstrate enhanced evidence and understanding of ZIKV and its impact on public health.

  13. Scoping Review of the Zika Virus Literature

    Science.gov (United States)

    2016-01-01

    The global primary literature on Zika virus (ZIKV) (n = 233 studies and reports, up to March 1, 2016) has been compiled using a scoping review methodology to systematically identify and characterise the literature underpinning this broad topic using methods that are documented, updateable and reproducible. Our results indicate that more than half the primary literature on ZIKV has been published since 2011. The articles mainly covered three topic categories: epidemiology of ZIKV (surveillance and outbreak investigations) 56.6% (132/233), pathogenesis of ZIKV (case symptoms/ outcomes and diagnosis) 38.2% (89/233) and ZIKV studies (molecular characterisation and in vitro evaluation of the virus) 18.5% (43/233). There has been little reported in the primary literature on ZIKV vectors (12/233), surveillance for ZIKV (13/233), diagnostic tests (12/233) and transmission (10/233). Three papers reported on ZIKV prevention/control strategies, one investigated knowledge and attitudes of health professionals and two vector mapping studies were reported. The majority of studies used observational study designs, 89.7% (209/233), of which 62/233 were case studies or case series, while fewer (24/233) used experimental study designs. Several knowledge gaps were identified by this review with respect to ZIKV epidemiology, the importance of potential non-human primates and other hosts in the transmission cycle, the burden of disease in humans, and complications related to human infection with ZIKV. Historically there has been little research on ZIKV; however, given its current spread through Australasia and the Americas, research resources are now being allocated to close many of the knowledge gaps identified in this scoping review. Future updates of this project will probably demonstrate enhanced evidence and understanding of ZIKV and its impact on public health. PMID:27244249

  14. Using SCOPE to identify potential regulatory motifs in coregulated genes.

    Science.gov (United States)

    Martyanov, Viktor; Gross, Robert H

    2011-05-31

    SCOPE is an ensemble motif finder that uses three component algorithms in parallel to identify potential regulatory motifs by over-representation and motif position preference. Each component algorithm is optimized to find a different kind of motif. By taking the best of these three approaches, SCOPE performs better than any single algorithm, even in the presence of noisy data. In this article, we utilize a web version of SCOPE to examine genes that are involved in telomere maintenance. SCOPE has been incorporated into at least two other motif finding programs and has been used in other studies. The three algorithms that comprise SCOPE are BEAM, which finds non-degenerate motifs (ACCGGT), PRISM, which finds degenerate motifs (ASCGWT), and SPACER, which finds longer bipartite motifs (ACCnnnnnnnnGGT). These three algorithms have been optimized to find their corresponding type of motif. Together, they allow SCOPE to perform extremely well. Once a gene set has been analyzed and candidate motifs identified, SCOPE can look for other genes that contain the motif which, when added to the original set, will improve the motif score. This can occur through over-representation or motif position preference. Working with partial gene sets that have biologically verified transcription factor binding sites, SCOPE was able to identify most of the rest of the genes also regulated by the given transcription factor. Output from SCOPE shows candidate motifs, their significance, and other information both as a table and as a graphical motif map. FAQs and video tutorials are available at the SCOPE web site which also includes a "Sample Search" button that allows the user to perform a trial run. Scope has a very friendly user interface that enables novice users to access the algorithm's full power without having to become an expert in the bioinformatics of motif finding. As input, SCOPE can take a list of genes, or FASTA sequences. These can be entered in browser text fields, or read from

  15. A test of reactive scope: Reducing reactive scope causes delayed wound healing.

    Science.gov (United States)

    DuRant, S E; Arciniega, M L; Bauer, C M; Romero, L M

    2016-09-15

    Reactive scope predicts that all animals have an adaptive ability to respond to stressors in their environment, termed reactive homeostasis, and that only when an animal's response to stressful stimuli exceeds a certain threshold (homeostatic overload) will stress have pathological effects. While this framework has successfully helped interpret effects of stressors on wildlife, no study has designed an experiment to directly test this framework. This study was designed to expose house sparrows (Passer domesticus) to treatments that would result in varying ranges of reactive homeostasis during chronic stress, which based on the reactive scope model should cause birds with the lowest reactive homeostasis range to exhibit signs of pathology during a subsequent challenge. To modulate the reactive homeostasis range, we altered allostatic load of birds by exposing them to chronic stress while either elevating, blocking, or not manipulating corticosterone. After concluding chronic stress treatments, birds were exposed to the subsequent challenge of a superficial wound. Individuals treated with corticosterone during chronic stress (high allostatic load) experienced the most pathology, including both weight loss and slower wound healing. Unmanipulated birds (medium allostatic load) also experienced weight loss but had normal healing rates, while birds with blocked corticosterone (low allostatic load) had minimal weight loss and normal healing rates. Our results indicate that increased allostatic load reduces the reactive homeostasis range, thereby causing individuals to cross the homeostatic overload threshold sooner, and thus support the reactive scope framework.

  16. A global attentional scope setting prioritizes faces for conscious detection.

    Science.gov (United States)

    Sun, Sol Z; Cant, Jonathan S; Ferber, Susanne

    2016-01-01

    The scope of visual attention is known to affect conscious object perception, with recent studies showing that a global attentional scope boosts holistic face processing, relative to a local scope. Here we show that attentional scope settings can also modulate the availability of information for conscious visual awareness. In an initial experiment, we show that adopting a global attentional scope accelerates conscious detection of initially invisible faces, presented under continuous flash suppression (CFS). Furthermore, face detection time was not modulated by attentional scope in a nonrivalrous control condition, which emulated the experience of CFS without inducing binocular rivalry. In a follow-up experiment, we report an exact replication of the original effect, as well as data suggesting that this effect is specific to upright faces, and is abolished when using both inverted faces and images of houses in an otherwise identical task. Thus, attentional scope settings can modulate the availability of information to conscious awareness, fundamentally altering the contents of our subjective visual experience. PMID:27089064

  17. A global attentional scope setting prioritizes faces for conscious detection.

    Science.gov (United States)

    Sun, Sol Z; Cant, Jonathan S; Ferber, Susanne

    2016-01-01

    The scope of visual attention is known to affect conscious object perception, with recent studies showing that a global attentional scope boosts holistic face processing, relative to a local scope. Here we show that attentional scope settings can also modulate the availability of information for conscious visual awareness. In an initial experiment, we show that adopting a global attentional scope accelerates conscious detection of initially invisible faces, presented under continuous flash suppression (CFS). Furthermore, face detection time was not modulated by attentional scope in a nonrivalrous control condition, which emulated the experience of CFS without inducing binocular rivalry. In a follow-up experiment, we report an exact replication of the original effect, as well as data suggesting that this effect is specific to upright faces, and is abolished when using both inverted faces and images of houses in an otherwise identical task. Thus, attentional scope settings can modulate the availability of information to conscious awareness, fundamentally altering the contents of our subjective visual experience.

  18. AuScope VLBI Project and Hobart 26-m Antenna

    Science.gov (United States)

    Lovell, Jim; Dickey, John; Reid, Brett; McCallum, Jamie; Shabala, Stas; Watson, Christopher; Ellingsen, Simon; Memin, Anthony

    2013-01-01

    This is a report on the activities carried out at the three AuScope VLBI observatories and the Hobart 26-m antenna. In 2012 the three AuScope 12-m antennas at Hobart (Hb), Katherine (Ke), and Yarragadee (Yg) completed their first full year of operations as an array. The Hobart 26-m antenna (Ho) continued to make a contribution to IVS, providing overlap with the Hb time series. In total the AuScope antennas and the Hobart 26 m observed for 146 antenna days in 2012. In this report we also briefly highlight our research activities during 2012 and our plans for 2013.

  19. Probiotics: definition, scope and mechanisms of action.

    Science.gov (United States)

    Reid, Gregor

    2016-02-01

    For a subject area of science, medicine and commerce to be so recently defined and investigated, few can compare to probiotics for the controversy they have incited. Barely a paper is published without the use of a different definition, or challenging the most used one, or proposing a different nuance of it. The situation has become even more surreal with the European Food and Safety Authority banning the word probiotic for use on labels. The reiteration of the FAO/WHO definition by the world's leading group of probiotic experts, should provide relative consistency in the near future, but what are the causes of these aberrations? This review will discuss the rationale for the definition, and the scope of the subject area and why alternatives emerge. While mechanisms of action are not widely proven, in vitro and some in vivo experiments support several. Ultimately, the goal of any field or product is to be understood by lay people and experts alike. Probiotics have come a long way in 100 years since Metchnikoff and 10 years since their globalization, but their evolution is far from over. PMID:27048893

  20. Cementitious waste option scoping study report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, A.E.; Taylor, D.D.

    1998-02-01

    A Settlement Agreement between the Department of Energy (DOE) and the State of Idaho mandates that all high-level radioactive waste (HLW) now stored at the Idaho Chemical Processing Plant (ICPP) on the Idaho National Engineering and Environmental Laboratory (INEEL) will be treated so that it is ready to be moved out of Idaho for disposal by a target date of 2035. This study investigates the nonseparations Cementitious Waste Option (CWO) as a means to achieve this goal. Under this option all liquid sodium-bearing waste (SBW) and existing HLW calcine would be recalcined with sucrose, grouted, canisterized, and interim stored as a mixed-HLW for eventual preparation and shipment off-Site for disposal. The CWO waste would be transported to a Greater Confinement Disposal Facility (GCDF) located in the southwestern desert of the US on the Nevada Test Site (NTS). All transport preparation, shipment, and disposal facility activities are beyond the scope of this study. CWO waste processing, packaging, and interim storage would occur over a 5-year period between 2013 and 2017. Waste transport and disposal would occur during the same time period.

  1. Oral care post stroke: a scoping review.

    Science.gov (United States)

    Kwok, C; McIntyre, A; Janzen, S; Mays, R; Teasell, R

    2015-01-01

    Health concerns post stroke may be the result of, or exacerbated by, neglected oral health care (OHC). However, OHC may be challenging post stroke due to hemiparesis, hemiplegia, a lack of coordination, and/or cognitive deficits. The objective of this study was to conduct a scoping review and summarise the current state of knowledge pertaining to OHC post stroke. A literature search was conducted using the multiple databases (MEDLINE, CINAHL, EMBASE, etc.). Combinations of multiple keywords were searched: oral, dental, health, care, hygiene, teeth, dentures, tooth brushing, stroke, cardiovascular health and cardiovascular disease. A grey literature search was also conducted. Articles included were those published in English between 1970 and July 2013, which focused on at least one aspect of OHC among a stroke population. For clinical trials, ≥50% of the sample must have sustained a stroke. In total, 60 articles met inclusion and focused on three primary area: (i) OHC Importance/Stroke Implications; (ii) Current Research; and (iii) Current Practice. It was found that OHC concerns are mainly related to mastication, dysphagia/nutrition, hygiene, prostheses and quality of life. Research indicates that there is limited specialised and individual care provided, and there are few assessment tools, guidelines and established protocols for oral health that are specific to the stroke population. Further, dental professionals' and nurses' knowledge of OHC is generally inadequate; hence, proper education for health professionals in acute and rehabilitation settings, patients, and caregivers has been discussed. PMID:25244419

  2. Probiotics: definition, scope and mechanisms of action.

    Science.gov (United States)

    Reid, Gregor

    2016-02-01

    For a subject area of science, medicine and commerce to be so recently defined and investigated, few can compare to probiotics for the controversy they have incited. Barely a paper is published without the use of a different definition, or challenging the most used one, or proposing a different nuance of it. The situation has become even more surreal with the European Food and Safety Authority banning the word probiotic for use on labels. The reiteration of the FAO/WHO definition by the world's leading group of probiotic experts, should provide relative consistency in the near future, but what are the causes of these aberrations? This review will discuss the rationale for the definition, and the scope of the subject area and why alternatives emerge. While mechanisms of action are not widely proven, in vitro and some in vivo experiments support several. Ultimately, the goal of any field or product is to be understood by lay people and experts alike. Probiotics have come a long way in 100 years since Metchnikoff and 10 years since their globalization, but their evolution is far from over.

  3. Cementitious waste option scoping study report

    International Nuclear Information System (INIS)

    A Settlement Agreement between the Department of Energy (DOE) and the State of Idaho mandates that all high-level radioactive waste (HLW) now stored at the Idaho Chemical Processing Plant (ICPP) on the Idaho National Engineering and Environmental Laboratory (INEEL) will be treated so that it is ready to be moved out of Idaho for disposal by a target date of 2035. This study investigates the nonseparations Cementitious Waste Option (CWO) as a means to achieve this goal. Under this option all liquid sodium-bearing waste (SBW) and existing HLW calcine would be recalcined with sucrose, grouted, canisterized, and interim stored as a mixed-HLW for eventual preparation and shipment off-Site for disposal. The CWO waste would be transported to a Greater Confinement Disposal Facility (GCDF) located in the southwestern desert of the US on the Nevada Test Site (NTS). All transport preparation, shipment, and disposal facility activities are beyond the scope of this study. CWO waste processing, packaging, and interim storage would occur over a 5-year period between 2013 and 2017. Waste transport and disposal would occur during the same time period

  4. The Scope of Numeracy after Five Years

    Directory of Open Access Journals (Sweden)

    H.L. Vacher

    2013-01-01

    Full Text Available The purpose of this editorial is to provide an efficient way for readers and potential authors to see (a what type of papers are published in this journal and (b what subjects are appropriate. The editorial consists mainly of about a dozen pages of tables including live links to the papers’ access/abstract pages to facilitate easy browsing. In the first table, the 85 papers that have been published in the journal’s first five years are classified into: review papers; research papers; case studies; essays; book reviews; columns; and editorials about the journal. In the second table, the papers are inventoried into overlapping sets on: assessment; QL and writing; the construct of QL; focused QL courses and curricula; QL across the curriculum; QL centers; algebra and calculus education; statistics education; intersections with science and engineering; intersections with social sciences; financial numeracy; health numeracy; math anxiety; and cognition. Browsing these links confirms what we said in the first editorial: the scope of Numeracy is huge.

  5. Magnetotactic bacteria and magnetosomes - Scope and challenges.

    Science.gov (United States)

    Jacob, Jobin John; Suthindhiran, K

    2016-11-01

    Geomagnetism aided navigation has been demonstrated by certain organisms which allows them to identify a particular location using magnetic field. This attractive technique to recognize the course was earlier exhibited in numerous animals, for example, birds, insects, reptiles, fishes and mammals. Magnetotactic bacteria (MTB) are one of the best examples for magnetoreception among microorganisms as the magnetic mineral functions as an internal magnet and aid the microbe to move towards the water columns in an oxic-anoxic interface (OAI). The ability of MTB to biomineralize the magnetic particles (magnetosomes) into uniform nano-sized, highly crystalline structure with uniform magnetic properties has made the bacteria an important topic of research. The superior properties of magnetosomes over chemically synthesized magnetic nanoparticles made it an attractive candidate for potential applications in microbiology, biophysics, biochemistry, nanotechnology and biomedicine. In this review article, the scope of MTB, magnetosomes and its challenges in research and industrial application have been discussed in brief. This article mainly focuses on the application based on the magnetotactic behaviour of MTB and magnetosomes in different areas of modern science. PMID:27524094

  6. The international scope of IAEA safeguards

    International Nuclear Information System (INIS)

    As a result of safeguards agreements under the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) and with States not Party to that Treaty, the Agency's safeguards coverage today is very extensive. According to the best information officially available to the Agency, there are only five States in the world besides the nuclear-weapon States that have significant nuclear activities which are not subject to Agency safeguards, namely Egypt, India, Israel, South Africa and Spain. Nevertheless, any State that is not a Party to the NPT or the Treaty for the Prohibition of Nuclear Weapons in Latin America (Tlatelolco Treaty) is free, in the absence of treaty obligations, to build or otherwise acquire unsafeguarded nuclear plant. Furthermore, there are significant differences between the NPT safeguards agreements and those with States not Party to the NPT, not only with regard to scope (NPT agreements cover all peaceful nuclear activities in the State, which in practice means all nuclear activities, while non-NPT agreements so far only cover particular plants or supply agreements) but also in technical and legal approach (NPT agreements reflect important advances in safeguards concepts indicated in the Treaty itself). (author)

  7. 12 CFR 715.1 - Scope of this part.

    Science.gov (United States)

    2010-01-01

    ... of the Supervisory Committee to obtain an annual audit of the credit union according to its charter... COMMITTEE AUDITS AND VERIFICATIONS § 715.1 Scope of this part. This part implements section 202(a)(6)(D)...

  8. 45 CFR 170.400 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION... FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.400 Basis and scope... and procedures related to the temporary certification program for health information...

  9. 42 CFR 410.3 - Scope of benefits.

    Science.gov (United States)

    2010-10-01

    ... SUPPLEMENTARY MEDICAL INSURANCE (SMI) BENEFITS General Provisions § 410.3 Scope of benefits. (a) Covered services. The SMI program helps pay for the following: (1) Medical and other health services such...

  10. 7 CFR 227.1 - General purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.1 General purpose and scope. The purpose of these regulations is to implement section 19 of the Child Nutrition Act... child nutrition programs as a learning experience....

  11. 49 CFR 1180.0 - Scope and purpose.

    Science.gov (United States)

    2010-10-01

    ... OF TRANSPORTATION RULES OF PRACTICE RAILROAD ACQUISITION, CONTROL, MERGER, CONSOLIDATION PROJECT, TRACKAGE RIGHTS, AND LEASE PROCEDURES General Acquisition Procedures § 1180.0 Scope and purpose. (a... followed in control, merger, acquisition, lease, trackage rights, and any other consolidation...

  12. 48 CFR 10.000 - Scope of part.

    Science.gov (United States)

    2010-10-01

    ... MARKET RESEARCH 10.000 Scope of part. This part prescribes policies and procedures for conducting market research to arrive at the most suitable approach to acquiring, distributing, and supporting supplies...

  13. 30 CFR 881.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... LAND RECLAMATION SUBSIDENCE AND STRIP MINE REHABILITATION, APPALACHIA § 881.1 Purpose and scope. The... rehabilitation of existing strip and surface mine areas under the authority of subsection (a)(1) of section...

  14. 49 CFR 178.700 - Purpose, scope and definitions.

    Science.gov (United States)

    2010-10-01

    ... PACKAGINGS IBC Performance-Oriented Standards § 178.700 Purpose, scope and definitions. (a) This subpart... pertain to the IBC standards in this subpart. (1) Body means the receptacle proper (including openings...

  15. 45 CFR 63.16 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION Financial Provisions § 63.16 Scope of subpart. This subpart sets forth supplemental financial provisions which apply to all grants awarded...

  16. 48 CFR 2917.500 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT TYPES SPECIAL CONTRACTING METHODS Interagency Acquisitions Under The Economy Act 2917.500 Scope of... of interagency acquisitions under the Economy Act (31 U.S.C. 1535) as prescribed by FAR 17.5....

  17. Scope of Collections Statement Ohio River Islands National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Scope of Collections Statement serves to define the holdings, present and future, of museum property that contributes directly to the mission of Ohio River...

  18. 32 CFR 320.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.1 Purpose and scope. (a) This part is published... whether the National Geospatial-Intelligence Agency (NGA) maintains or has disclosed a record...

  19. 5 CFR 179.301 - Scope of regulations.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Scope of regulations. 179.301 Section 179.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS... in 4 CFR 102.3....

  20. 78 FR 36748 - Caribbean Fishery Management Council; Scoping Meetings

    Science.gov (United States)

    2013-06-19

    ...@yahoo.com , or the Council office at (787) 766-5926 to obtain copies. Written comments can be sent to... graciela_cfmc@yahoo.com . The scoping meetings will be held on the following dates and locations: In...

  1. 12 CFR 216.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... CONSUMER FINANCIAL INFORMATION (REGULATION P) § 216.1 Purpose and scope. (a) Purpose. This part governs the... who obtain financial products or services primarily for personal, family, or household purposes...

  2. 12 CFR 716.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... CONSUMER FINANCIAL INFORMATION § 716.1 Purpose and scope. (a) Purpose. This part governs the treatment of... services for personal, family or household purposes. This part does not apply to information...

  3. 12 CFR 332.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... OF CONSUMER FINANCIAL INFORMATION § 332.1 Purpose and scope. (a) Purpose. This part governs the... who obtain financial products or services primarily for personal, family, or household purposes...

  4. 31 CFR 29.301 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... determination and review of eligibility and payments, and financial management, are beyond the scope of this... illustrative examples of sample computations to show the application of the general principles to...

  5. 40 CFR 255.1 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... types (residential and commercial solid waste, hazardous wastes, industrial sludges and pretreatment... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES IDENTIFICATION OF REGIONS AND AGENCIES FOR SOLID WASTE MANAGEMENT General Provisions § 255.1 Scope and purpose. (a)...

  6. Economies of scope in Danish primary care practices

    DEFF Research Database (Denmark)

    Kristensen, Troels; Rose Olsen, Kim

    2011-01-01

    Aim: We analyze total operating costs and activities in Danish General Practice units to assess whether there are unexploited economies of scope in the production of primary care services. Methods: We apply stochastic frontier analysis to derive cost functions and associated cost complementarities...... between GP services and overall economies of scope. Data: Cross-section data for a sample of 331 primary care practices with 1-8 GPs from the year 2006. This is a unique combined dataset consisting of survey and register data. Results: We find a trend towards cost complementarities between the production...... economies of scope in the production of GP services. Conclusions: Our preliminary results show that there were overall economies of scope associated with the joint production of a) standard consultations, b) email/phone consultations and c) home visits. Cost complementarities between standard consultations...

  7. 50 CFR 654.1 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF COMMERCE STONE CRAB FISHERY OF THE GULF OF MEXICO General Measures § 654.1 Purpose and scope... of the Gulf of Mexico, prepared by the Gulf of Mexico Fishery Management Council under the...

  8. 14 CFR 1204.400 - Scope of subpart.

    Science.gov (United States)

    2010-01-01

    ... Business Policy § 1204.400 Scope of subpart. This subpart establishes NASA's small business policy and outlines the delegation of authority in implementing this policy as required by Federal law....

  9. Meta-Research: Broadening the Scope of PLOS Biology.

    Science.gov (United States)

    Kousta, Stavroula; Ferguson, Christine; Ganley, Emma

    2016-01-01

    In growing recognition of the importance of how scientific research is designed, performed, communicated, and evaluated, PLOS Biology announces a broadening of its scope to cover meta-research articles.

  10. 48 CFR 4.500 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... MATTERS Electronic Commerce in Contracting 4.500 Scope of subpart. This subpart provides policy and procedures for the establishment and use of electronic commerce in Federal acquisition as required by...

  11. 28 CFR 549.60 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... Hunger Strikes, Inmate § 549.60 Purpose and scope. The Bureau of Prisons provides guidelines for the medical and administrative management of inmates who engage in hunger strikes. It is the responsibility...

  12. 48 CFR 2110.7000 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING SPECIFICATIONS, STANDARDS, AND OTHER PURCHASE DESCRIPTIONS Contract Specifications 2110.7000 Scope of subpart. This subpart prescribes mandatory specifications for performance under FEGLI Program contracts....

  13. 48 CFR 42.1500 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 42.1500 Scope of subpart... fees under award or incentive fee contracts. However, the fee amount paid to contractors should be... fee determinations....

  14. 10 CFR 715.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... production facility,” in section 416(a)(2)(B) of the Clean Air Act Amendments of 1990, 42 U.S.C. 7651o(a)(2... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and scope. 715.1 Section 715.1 Energy DEPARTMENT OF ENERGY DEFINITION OF NON-RECOURSE PROJECT-FINANCED § 715.1 Purpose and scope. This part sets...

  15. De betekenis van marktstructuren voor de scope van de onderneming

    OpenAIRE

    Commandeur, Harry

    2003-01-01

    textabstractDifferent market structures and value systems give insight into the changing environment in which companies operate. In this inaugural address the central question is: What is the influence of market structures on the scope of the firm?The objective is to give meaningful contributions to the clear understanding of market structures that are of specific importance at the meso level. To gain more insights into the scope of the firm a framework is constructed based on the three dimen...

  16. Scoping review of patient-centered care approaches in healthcare

    OpenAIRE

    Constand, Marissa K; MacDermid, Joy C; Dal Bello-Haas, Vanina; Law, Mary

    2014-01-01

    Background The purpose of this scoping review was to describe how three tenants of patient-centered care provision: communication, partnership, and health promotion are addressed in patient-centered care models/frameworks across the literature. Methods A scoping review of literature published in English since 1990 was conducted using Medline, CINAHL, and EMBASE. A key term search strategy was employed using “patient-centered care”, “client-centered care”, “framework” and “model” to identify r...

  17. Scoping accident(s) for emergency planning

    International Nuclear Information System (INIS)

    At the request of the Conference of State Radiation Control Program Director's (CRCPD), in November 1976 the U.S. Nuclear Regulatory Commission formed a joint Task Force with representatives of the U.S. Environmental Protection Agency to answer a number of questions posed by the States regarding emergency planning. This Task Force held monthly meetings through November 1977. In December 1977 a draft report was prepared for limited distribution for review and comment by selected State and local organizations. The NRC/EPA Task Force deliberations centered on the CRCPD request for '... a determination of the most severe accident basis for which radiological emergency response plans should be developed by offsite agencies...' in the vicinity of nuclear power plants. Federal Interagency guidance to the States in this regard has been that the scoping accident should be the most serious conservatively analyzed accident considered for siting purposes, as exemplified in the Commission's Regulations at 10 CFR Part 100 and the NRC staffs Regulatory Guides 1.3 and 1.4, and as presented in license applicant's Safety Analysis Reports and the USNRC Staffs Safety Evaluation Reports. The draft report of the Task Force amplifies on this recommendation: to present a clearer picture of its import and introduces the concept of protective action zones (PAZs) within which detailed emergency plans should be developed; one zone for the plume exposure pathway and a second, larger zone for contamination pathways. The time dependence of potential releases and atmospheric transport, and important radionuclide groups of possible import are also discussed in the draft Task Force report. A status report regarding this effort, as of June 1978, will be presented. (author)

  18. SOFTWARE PROJECT SCOPE VERIFICATION THROUGH DELIVERABLE-ORIENTED WORK BREAKDOWN STRUCTURE

    Directory of Open Access Journals (Sweden)

    Robert T. Hans

    2013-02-01

    Full Text Available Software project scope verification is a very important process in project scope management and it needs to be performed properly so as to avoid project rework and to promote better project scope control. Moreover, software scope verification is crucial in the process of delivering exactly what the customer requested and minimizing project scope changes. Well defined software scope eases the process of scope verification and contributes to project success. Furthermore, a deliverable-oriented WBS provides a road map to a well defined software scope of work. It is on the basis of this that this paper extends the use of deliverableoriented WBS to that of scope verification process. This paper argues that a deliverableoriented WBS is a tool for software scope verification

  19. Demand Responsive Lighting: A Scoping Study

    Energy Technology Data Exchange (ETDEWEB)

    Rubinstein, Francis; Kiliccote, Sila

    2007-01-03

    The objective of this scoping study is: (1) to identify current market drivers and technology trends that can improve the demand responsiveness of commercial building lighting systems and (2) to quantify the energy, demand and environmental benefits of implementing lighting demand response and energy-saving controls strategies Statewide. Lighting systems in California commercial buildings consume 30 GWh. Lighting systems in commercial buildings often waste energy and unnecessarily stress the electrical grid because lighting controls, especially dimming, are not widely used. But dimmable lighting equipment, especially the dimming ballast, costs more than non-dimming lighting and is expensive to retrofit into existing buildings because of the cost of adding control wiring. Advances in lighting industry capabilities coupled with the pervasiveness of the Internet and wireless technologies have led to new opportunities to realize significant energy saving and reliable demand reduction using intelligent lighting controls. Manufacturers are starting to produce electronic equipment--lighting-application specific controllers (LAS controllers)--that are wirelessly accessible and can control dimmable or multilevel lighting systems obeying different industry-accepted protocols. Some companies make controllers that are inexpensive to install in existing buildings and allow the power consumed by bi-level lighting circuits to be selectively reduced during demand response curtailments. By intelligently limiting the demand from bi-level lighting in California commercial buildings, the utilities would now have an enormous 1 GW demand shed capability at hand. By adding occupancy and light sensors to the remotely controllable lighting circuits, automatic controls could harvest an additional 1 BkWh/yr savings above and beyond the savings that have already been achieved. The lighting industry's adoption of DALI as the principal wired digital control protocol for dimming ballasts

  20. USArray Siting Outreach: Telling the EarthScope Story

    Science.gov (United States)

    Dorr, P. M.; Taber, J. J.; McQuillan, P.; Busby, R. W.; Woodward, R.

    2013-12-01

    USArray has engaged in a variety of activities that involve students in and inform the general public about EarthScope. Examples include the highly successful Transportable Array Student Siting Program that employed students and faculty from colleges and universities in the identification of sites for future Transportable Array stations in their region, and a range of informal education and media opportunities where information about EarthScope and its discoveries are shared with educators and the public. During the course of eight summers, more than 135 students from about 55 institutions conducted site reconnaissance for nearly 1375 sites from the West Coast to the East Coast, and from the Gulf of Mexico to the Great Lakes and southern Canada. While telling the EarthScope story, students who participated in the program increased their professional skills and deepened their personal growth. Other students had opportunities to engage in EarthScope-related research as part of the Research Experiences for Undergraduates program. Several EarthScope-focused outreach products for the public and educational audiences have been developed including Ground Motion Visualizations, EarthScope-centric and regional content sets for the IRIS Active Earth Monitor (AEM), and animations of earth processes. A kiosk loan program has helped to broadly disseminate the AEM displays. There have also been articles published in university, local and regional newspapers; stories appearing in national and international print and broadcast media; and documentaries produced by some of the world's most respected scientific and educational production companies that have included a segment about EarthScope and the Transportable Array. Over the next five years, USArray will be deploying and operating Transportable Array stations in Alaska and western Canada. This challenging environment will offer new opportunities to connect with communities throughout the region including native populations.

  1. Automated scoping methodology for liquid metal natural circulation small reactor

    Energy Technology Data Exchange (ETDEWEB)

    Son, Hyung M.; Suh, Kune Y., E-mail: kysuh@snu.ac.kr

    2014-07-01

    Highlights: • Automated scoping methodology for natural circulation small modular reactor is developed. • In-house code is developed to carry out system analysis and core geometry generation during scoping. • Adjustment relations are obtained to correct the critical core geometry out of diffusion theory. • Optimized design specification is found using objective function value. • Convex hull volume is utilized to quantify the impact of different constraints on the scope range. - Abstract: A novel scoping method is proposed that can automatically generate design variable range of the natural circulation driven liquid metal cooled small reactor. From performance requirements based upon Generation IV system roadmap, appropriate structure materials are selected and engineering constraints are compiled based upon literature. Utilizing ASME codes and standards, appropriate geometric sizing criteria on constituting components are developed to ensure integrity of the system during its lifetime. In-house one dimensional thermo-hydraulic system analysis code is developed based upon momentum integral model and finite element methods to deal with non-uniform descritization of temperature nodes for convection and thermal diffusion equation of liquid metal coolant. In order to quickly generate critical core dimensions out of given unit cell information, an adjustment relation that relates the critical geometry estimated from one-group diffusion and that from MCNP code is constructed and utilized throughout the process. For the selected unit cell dimension ranges, burnup calculations are carried out to check the cores can generate energy over the reactor lifetime. Utilizing random method, sizing criteria, and in-house analysis codes, an automated scoping methodology is developed. The methodology is applied to nitride fueled integral type lead cooled natural circulation reactor concept to generate design scopes which satisfies given constraints. Three dimensional convex

  2. Scale and scope economies among health maintenance organizations.

    Science.gov (United States)

    Wholey, D; Feldman, R; Christianson, J B; Engberg, J

    1996-12-01

    We examine scale and scope economics among Group and IPA Health Maintenance Organizations (HMOs) over the period 1988 to 1991 using a national sample of HMOs. We allow for the multiproduct nature of HMO production by estimating the cost of producing a member month of non-Medicare and Medicare coverage, and we examine the effect of HMO market structure on costs. We find that HMOs benefit from scale economies. There are scope diseconomies associated with providing both non-Medicare and Medicare products. Group HMOs in more competitive markets have lower costs but IPA costs are not affected by competition.

  3. Evaluation of full-scope simulator testing methods

    International Nuclear Information System (INIS)

    This report discusses the use of full scope nuclear power plant simulators in licensing examinations for Unit First Operators of CANDU reactors. The existing literature is reviewed, and an annotated bibliography of the more important sources provided. Since existing methods are judged inadequate, conceptual bases for designing a system for licensing are discussed, and a method proposed which would make use of objective scoring methods based on data collection in full-scope simulators. A field trial of such a method is described. The practicality of such a method is critically discussed and possible advantages of subjective methods of evaluation considered. (author). 32 refs., 1 tab., 4 figs

  4. The Scope of Gene Patent Protection and the TRIPS Agreement

    DEFF Research Database (Denmark)

    Sommer, Tine

    2007-01-01

    The Scope of Gene Patent Protection and the TRIPS Agreement - An Exclusively Nondiscriminatory Approach?   Gene patenting in Europe has provoked much debate both before and since the adoption of Directive 98/44/EC on the legal protection of biotechnological inventions. Some of the major points...... of discussion have been focused on the scope of protection (e.g. purpose-bound protection) and gene patents being subject to a specific DNA regime on patent rights. The Directive can be interpreted as favouring such a solution, but so far the European Commission has decided neither to support nor reject...

  5. Double-Scope Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia: The First Trial of a New Double-Scope POEM.

    Science.gov (United States)

    Hong, Hee Jin; Song, Ga Won; Ko, Weon Jin; Kim, Won Hee; Hahm, Ki Baik; Hong, Sung Pyo; Cho, Joo Young

    2016-07-01

    With the accumulation of clinical trials demonstrating its efficacy and safety, peroral endoscopic myotomy (POEM) has emerged as a less invasive treatment option for esophageal achalasia compared with laparoscopic Heller myotomy. However, the difficulty in determining the exact extent of myotomy, a critical factor associated with the success and safety of the procedure, remains a limitation. Although the various endoscopic landmarks and ancillary techniques have been applied, none of these has been proven sufficient. As a solution for this limitation, the double-scope POEM technique with a second endoscope to assure the exact length of the submucosal tunnel has been applied since 2014. Before double-scope POEM was introduced, the second endoscope was applied only to confirm the accuracy of the procedure. In the present study, we performed double-scope POEM in the treatment of esophageal achalasia through a novel procedure of simultaneous application of the second endoscope to assist in the conventional POEM procedure.

  6. Scoping of flood hazard mapping needs for Kennebec County, Maine

    Science.gov (United States)

    Dudley, Robert W.; Schalk, Charles W.

    2006-01-01

    This report was prepared by the U.S. Geological Survey (USGS) Maine Water Science Center as the deliverable for scoping of flood hazard mapping needs for Kennebec County, Maine, under Federal Emergency Management Agency (FEMA) Inter-Agency Agreement Number HSFE01-05-X-0018. This section of the report explains the objective of the task and the purpose of the report. The Federal Emergency Management Agency (FEMA) developed a plan in 1997 to modernize the FEMA flood mapping program. FEMA flood maps delineate flood hazard areas in support of the National Flood Insurance Program (NFIP). FEMA's plan outlined the steps necessary to update FEMA's flood maps for the nation to a seamless digital format and streamline FEMA's operations in raising public awareness of the importance of the maps and responding to requests to revise them. The modernization of flood maps involves conversion of existing information to digital format and integration of improved flood hazard data as needed. To determine flood mapping modernization needs, FEMA has established specific scoping activities to be done on a county-by-county basis for identifying and prioritizing requisite flood-mapping activities for map modernization. The U.S. Geological Survey (USGS), in cooperation with FEMA and the Maine State Planning Office Floodplain Management Program, began scoping work in 2005 for Kennebec County. Scoping activities included assembling existing data and map needs information for communities in Kennebec County (efforts were made to not duplicate those of pre-scoping completed in March 2005), documentation of data, contacts, community meetings, and prioritized mapping needs in a final scoping report (this document), and updating the Mapping Needs Update Support System (MNUSS) Database or its successor with information gathered during the scoping process. The average age of the FEMA floodplain maps in Kennebec County, Maine is 16 years. Most of these studies were in the late 1970's to the mid 1980s

  7. Scoping of flood hazard mapping needs for Somerset County, Maine

    Science.gov (United States)

    Dudley, Robert W.; Schalk, Charles W.

    2006-01-01

    This report was prepared by the U.S. Geological Survey (USGS) Maine Water Science Center as the deliverable for scoping of flood hazard mapping needs for Somerset County, Maine, under Federal Emergency Management Agency (FEMA) Inter-Agency Agreement Number HSFE01-05-X-0018. This section of the report explains the objective of the task and the purpose of the report. The Federal Emergency Management Agency (FEMA) developed a plan in 1997 to modernize the FEMA flood mapping program. FEMA flood maps delineate flood hazard areas in support of the National Flood Insurance Program (NFIP). FEMA's plan outlined the steps necessary to update FEMA's flood maps for the nation to a seamless digital format and streamline FEMA's operations in raising public awareness of the importance of the maps and responding to requests to revise them. The modernization of flood maps involves conversion of existing information to digital format and integration of improved flood hazard data as needed. To determine flood mapping modernization needs, FEMA has established specific scoping activities to be done on a county-by-county basis for identifying and prioritizing requisite flood-mapping activities for map modernization. The U.S. Geological Survey (USGS), in cooperation with FEMA and the Maine State Planning Office Floodplain Management Program, began scoping work in 2005 for Somerset County. Scoping activities included assembling existing data and map needs information for communities in Somerset County (efforts were made to not duplicate those of pre-scoping completed in March 2005), documentation of data, contacts, community meetings, and prioritized mapping needs in a final scoping report (this document), and updating the Mapping Needs Update Support System (MNUSS) Database or its successor with information gathered during the scoping process. The average age of the FEMA floodplain maps in Somerset County, Maine is 18.1 years. Most of these studies were in the late 1970's to the mid 1980

  8. 40 CFR 725.1 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Scope and purpose. 725.1 Section 725.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING... and 725.428), test marketing activities (see § 725.300), and research and development...

  9. 44 CFR 352.20 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Purpose and scope. 352.20 Section 352.20 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS COMMERCIAL NUCLEAR POWER PLANTS: EMERGENCY PREPAREDNESS PLANNING...

  10. 44 CFR 352.2 - Scope, purpose and applicability.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope, purpose and applicability. 352.2 Section 352.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS COMMERCIAL NUCLEAR POWER PLANTS: EMERGENCY PREPAREDNESS...

  11. 44 CFR 351.3 - Limitation of scope.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Limitation of scope. 351.3 Section 351.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS RADIOLOGICAL EMERGENCY PLANNING AND PREPAREDNESS General § 351.3...

  12. 24 CFR 266.125 - Scope and nature of sanctions.

    Science.gov (United States)

    2010-04-01

    ... mortgagee approval be withdrawn pursuant to 24 CFR part 25 and/or that penalties be imposed pursuant to 24 CFR part 30; (7) Require additional financial or other reports as may be necessary to monitor the... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Scope and nature of sanctions....

  13. 24 CFR 100.144 - Scope of privilege.

    Science.gov (United States)

    2010-04-01

    ... DISCRIMINATORY CONDUCT UNDER THE FAIR HOUSING ACT Discrimination in Residential Real Estate-Related Transactions... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Scope of privilege. 100.144 Section 100.144 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE...

  14. 34 CFR 682.700 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... basis of handicap), which is governed by 34 CFR part 104; or (iv) Title IX of the Education Amendments of 1972 (relating to sex discrimination), which is governed by 34 CFR part 106. (c) This subpart does... 34 Education 3 2010-07-01 2010-07-01 false Purpose and scope. 682.700 Section 682.700...

  15. A new scope for the Netherlands Journal of Agricultural Science

    OpenAIRE

    Jongen, W.M.F.; Struik, P. C.; Wienk, J.F.

    2002-01-01

    This paper first looks at the changes in agricultural research structures, research questions and research culture in the Netherlands. In the context of these changes, the future scope, readership and editorial policy of the Netherlands Journal of Agricultural Science are discussed.

  16. 45 CFR 1705.1 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Purpose and scope. 1705.1 Section 1705.1 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL COMMISSION ON LIBRARIES AND... Libraries and Information Science (hereafter, the Commission)....

  17. 42 CFR 422.1 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... PROGRAM MEDICARE ADVANTAGE PROGRAM General Provisions § 422.1 Basis and scope. (a) Basis. This part is... enrollment. 1852—Benefits and beneficiary protections. 1853—Payments to Medicare Advantage (MA) organizations..., limitations, and procedures for Medicare services furnished, or paid for, by Medicare Advantage...

  18. 5 CFR 293.101 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... RECORDS Basic Policies on Maintenance of Personnel Records § 293.101 Purpose and scope. (a) This subpart..., dissemination, and safeguarding of personnel records which the Office of Personnel Management requires agencies to maintain in the personnel management or personnel policy setting process. (b) Agencies in...

  19. 44 CFR 6.1 - Purpose and scope of part.

    Science.gov (United States)

    2010-10-01

    ... records maintained by the Federal Emergency Management Agency (FEMA) which are subject to the provision of...). These policies and procedures govern only those records as defined in § 6.2. Policies and procedures... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Purpose and scope of part....

  20. 45 CFR 674.2 - Scope and applicability.

    Science.gov (United States)

    2010-10-01

    ... the Antarctic Treaty where one of the purposes of the expedition is to collect meteorites in... 45 Public Welfare 3 2010-10-01 2010-10-01 false Scope and applicability. 674.2 Section 674.2 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION...

  1. 42 CFR 407.1 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... SUPPLEMENTARY MEDICAL INSURANCE (SMI) ENROLLMENT AND ENTITLEMENT General Provisions § 407.1 Basis and scope. (a) Statutory basis. The supplementary medical insurance (SMI) program is authorized by Part B of title XVIII of... pay the SMI premiums for, eligible individuals who are also eligible for cash assistance or...

  2. 41 CFR 105-1.100 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 105-1.100 Section 105-1.100 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System §...

  3. 49 CFR 193.2001 - Scope of part.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES... LNG facilities used in the transportation of gas by pipeline that is subject to the pipeline safety... 49 Transportation 3 2010-10-01 2010-10-01 false Scope of part. 193.2001 Section...

  4. 20 CFR 404.1601 - Purpose and scope.

    Science.gov (United States)

    2010-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determinations of Disability General Provisions § 404.1601 Purpose and scope. This subpart describes the... disability for the Commissioner under title II of the Act. It also establishes the...

  5. 20 CFR 404.1501 - Scope of subpart.

    Science.gov (United States)

    2010-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness General § 404.1501 Scope of subpart. In order for you to become entitled to any benefits based upon disability or blindness or to have a period of disability established,...

  6. 45 CFR 1340.1 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT General Provisions § 1340.1 Purpose and scope. (a) This part implements the Child Abuse Prevention and Treatment Act... expand child abuse and neglect prevention and treatment activities. (b) The National Center on...

  7. cyanoScope: Mapping cyanobacteria one slide at a time

    Science.gov (United States)

    cyanoScope is a new initiative for engaging the public, and particularly citizen scientists, to assist with mapping potentially harmful algal blooms throughout New England. Cyanobacteria are important members of the phytoplankton assemblages in lakes. In most situations these p...

  8. Building "Applied Linguistic Historiography": Rationale, Scope, and Methods

    Science.gov (United States)

    Smith, Richard

    2016-01-01

    In this article I argue for the establishment of "Applied Linguistic Historiography" (ALH), that is, a new domain of enquiry within applied linguistics involving a rigorous, scholarly, and self-reflexive approach to historical research. Considering issues of rationale, scope, and methods in turn, I provide reasons why ALH is needed and…

  9. Chemical Abstracts Service Chemical Registry System: History, Scope, and Impacts.

    Science.gov (United States)

    Weisgerber, David W.

    1997-01-01

    Describes the history, scope, and applications of the Chemical Abstracts Service Chemical Registry System, a computerized database that uniquely identifies chemical substances on the basis of their molecular structures. Explains searching the system is and discusses its use as an international resource. (66 references) (Author/LRW)

  10. 29 CFR 801.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 General § 801.1 Purpose and scope. (a) Effective December 27, 1988, the Employee Polygraph Protection Act of 1988 (EPPA or the Act) prohibits most private employers... tests either for pre-employment screening or during the course of employment. Polygraph tests, but...

  11. 12 CFR 4.11 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... banking industry and the public. (b) Scope. (1) This subpart describes the information that the FOIA... procedures that the OCC follows, in accordance with Executive Order 12600 (3 CFR, 1987 Comp., p. 235), when... requesting records from the OCC pursuant to the Privacy Act should refer to 31 CFR part 1, subpart C,...

  12. The scope for policy reforms in rural microfinance

    OpenAIRE

    Sharma, Manohar

    2000-01-01

    This brief considers the scope for policy action in seven areas: (1) regulation of microfinance institutions, (2) provision of saving services, (3) product innovation, (4) organizational issues in microfinance, (5) poverty impact of microfinance, (6) agricultural finance, and (7) subsidy and sustainability issues.

  13. 48 CFR 1819.7301 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs 1819.7301 Scope of subpart. The Small Business Innovation Research (SBIR... of the Small Business Act codified at 15 U.S.C. 631, as amended, and the Small Business...

  14. 45 CFR 307.0 - Scope of this part.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Scope of this part. 307.0 Section 307.0 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT ENFORCEMENT SYSTEMS §...

  15. Economies of Scale and Scope in Australian Higher Education

    Science.gov (United States)

    Worthington, A. C.; Higgs, H.

    2011-01-01

    This paper estimates economies of scale and scope for 36 Australian universities using a multiple-input, multiple-output cost function over the period 1998-2006. The three inputs included in the analysis are full-time equivalent academic and non-academic staff and physical capital. The five outputs are undergraduate, postgraduate and PhD…

  16. Economies of scale and scope in mental health care

    NARCIS (Netherlands)

    Wilschut, J.A.; Van Hulst, B.L.; Blank, J.L.T.

    2012-01-01

    Economies of scale and scope are usually derived under the assumption that the set of production possibilities are shared by all firms in an industry irrespective of whether they specialize in a single output or not. Mental health care institutions in the Netherlands vary substantially in the scale

  17. Do Liberal Arts Colleges Exhibit Economies of Scale and Scope?

    Science.gov (United States)

    Koshal, Rajindar K.; Koshal, Manjulika

    2000-01-01

    Empirically estimates a multiple-product fixed total cost function and output relationship for 295 U.S. private liberal-arts colleges. Statistical results suggest that there are economies of scale and scope in higher education. Research at such colleges is not cost-effective. (Contains 31 references.) (MLH)

  18. 13 CFR 306.4 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... centers (“University Centers”) that provide technical assistance to public and private sector... TRAINING, RESEARCH AND TECHNICAL ASSISTANCE INVESTMENTS University Center Economic Development Program § 306.4 Purpose and scope. The University Center Economic Development Program is intended to...

  19. 48 CFR 32.400 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 32.400 Scope of subpart. This subpart... include policies and procedures for advance payments for the types of transactions listed in 32.404. This subpart does not apply to commercial advance payments, which are subject to subpart 32.2....

  20. 41 CFR 101-1.100 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of subpart. 101-1.100 Section 101-1.100 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System §...

  1. 41 CFR 101-1.4900 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of subpart. 101-1.4900 Section 101-1.4900 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.49-Illustrations of...

  2. 13 CFR 306.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ...) Provide management and operational assistance; (7) Establish business outreach centers; (8) Disseminate... business. (c) EDA may identify specific training, research or technical assistance Projects it will fund... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Purpose and scope. 306.1...

  3. 40 CFR 160.1 - Scope and applicability.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Scope and applicability. 160.1 Section 160.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD... for research or marketing permits for pesticide products regulated by the EPA. This part is...

  4. 40 CFR 725.300 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Scope and purpose. 725.300 Section 725.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Exemptions for Test Marketing § 725.300...

  5. 10 CFR 490.300 - Purpose and Scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and Scope. 490.300 Section 490.300 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fuel Provider... vehicles acquired by alternative fuel providers must be alternative fueled vehicles....

  6. 10 CFR 490.801 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 490.801 Section 490.801 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Compliance § 490... States and alternative fuel providers to petition for alternative compliance waivers from the...

  7. 16 CFR 1305.1 - Scope and application.

    Science.gov (United States)

    2010-01-01

    ... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF... 9 of the Consumer Product Safety Act (CPSA) (15 U.S.C. 2057 and 2058). This ban applies to... ashes also come within the scope of this ban....

  8. 16 CFR 1302.1 - Scope and application.

    Science.gov (United States)

    2010-01-01

    ... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF... Consumer Product Safety Act (CPSA) (15 U.S.C. 2057 and 2058). This ban applies to those extremely flammable... hardware stores, for sale to consumers would be included in the scope of the ban even though such...

  9. 10 CFR 73.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... waterborne vehicle bomb assault, which may be coordinated with an external assault; and (v) A cyber attack... with an external assault; and (v) A cyber attack. (b) Scope. (1) This part prescribes requirements for... affecting § 73.1, see the List of CFR Sections Affected, which appears in the Finding Aids section of...

  10. 50 CFR 635.1 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Purpose and scope. 635.1 Section 635.1 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION... shark regulations govern conservation and management of sharks in the management unit, under...

  11. De betekenis van marktstructuren voor de scope van de onderneming

    NARCIS (Netherlands)

    H.R. Commandeur (Harry)

    2003-01-01

    textabstractDifferent market structures and value systems give insight into the changing environment in which companies operate. In this inaugural address the central question is: What is the influence of market structures on the scope of the firm?The objective is to give meaningful contributions to

  12. 10 CFR 490.200 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 490.200 Section 490.200 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Mandatory State Fleet... duty motor vehicles acquired for State fleets be alternative fueled vehicles....

  13. 10 CFR 490.500 - Purpose and Scope.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and Scope. 490.500 Section 490.500 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle... 508 of the Act, which provides for the allocation of credits to fleets or covered persons who...

  14. 48 CFR 50.000 - Scope of part.

    Science.gov (United States)

    2010-10-01

    ... as a qualified anti-terrorism technology as defined in the Support Anti-terrorism by Fostering... promote development and use of anti-terrorism technologies. ... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT 50.000 Scope of part. This part— (a)(1) Prescribes...

  15. 48 CFR 50.200 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.200 Scope of subpart. This subpart implements the Support Anti-terrorism by Fostering Effective Technologies Act of 2002 (SAFETY Act) liability protections to promote development and use of...

  16. 29 CFR 1912a.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) NATIONAL ADVISORY COMMITTEE ON OCCUPATIONAL SAFETY AND HEALTH § 1912a.1 Purpose and scope. (a) Section 7(a) of the Williams-Steiger Occupational Safety and Health Act of 1970 establishes a...

  17. 10 CFR 436.40 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... OF ENERGY ENERGY CONSERVATION FEDERAL ENERGY MANAGEMENT AND PLANNING PROGRAMS Agency Procurement of Energy Efficient Products § 436.40 Purpose and scope. This subpart provides guidance to promote the procurement of energy efficient products by Federal agencies and promote procurement practices...

  18. 34 CFR 668.71 - Scope and special definitions.

    Science.gov (United States)

    2010-07-01

    ... substantial misrepresentation made by that institution regarding the nature of its educational program, its... 34 Education 3 2010-07-01 2010-07-01 false Scope and special definitions. 668.71 Section 668.71... and special definitions. (a) This subpart establishes the standards and rules by which the...

  19. 30 CFR 202.350 - Scope and definitions.

    Science.gov (United States)

    2010-07-01

    ... ROYALTIES Geothermal Resources § 202.350 Scope and definitions. (a) This subpart is applicable to all geothermal resources produced from Federal geothermal leases issued pursuant to the Geothermal Steam Act of 1970, as amended (30 U.S.C. 1001 et seq.). (b) The definitions in 30 CFR 206.351 are applicable to...

  20. 28 CFR 540.70 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 540.70 Section 540.70 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT CONTACT WITH... activity. The term publication, as used in this subpart, means a book, booklet, pamphlet, or...

  1. 5 CFR 1201.72 - Explanation and scope of discovery.

    Science.gov (United States)

    2010-01-01

    ... location of persons with knowledge of relevant facts. Discovery requests that are directed to nonparties... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Explanation and scope of discovery. 1201... PROCEDURES PRACTICES AND PROCEDURES Procedures for Appellate Cases Discovery § 1201.72 Explanation and...

  2. 12 CFR 227.11 - Authority, purpose, and scope.

    Science.gov (United States)

    2010-01-01

    ... credit to consumers. (c) Scope. This subpart applies to all banks and their subsidiaries, except savings... Comptroller of the Currency, in the case of national banks, banks operating under the code of laws for the... in section 1(b) of the International Banking Act of 1978 (12 U.S.C. 3101). Effective Date Note: At...

  3. 5 CFR 180.101 - Scope and purpose.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Scope and purpose. 180.101 Section 180.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EMPLOYEES...' Claims Act of 1964, 31 U.S.C. 240 to 243, authorizes the Director, Office of Personnel Management...

  4. 42 CFR 426.100 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Basis and scope. 426.100 Section 426.100 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM REVIEW OF NATIONAL COVERAGE DETERMINATIONS AND LOCAL COVERAGE DETERMINATIONS...

  5. 7 CFR 25.1 - Applicability and scope.

    Science.gov (United States)

    2010-01-01

    ... Agencies Appropriations Act, 1999 (Public Law 105-277) (Round IIS), and the Community Renewal Tax Relief... Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES General Provisions § 25.1 Applicability and scope. (a) Applicability. This part contains policies and...

  6. 4 CFR 28.41 - Explanation, scope and methods.

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Explanation, scope and methods. 28.41 Section 28.41 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL... relevant to the issue under review, including the existence, description, nature, custody, condition...

  7. 28 CFR 544.30 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Inmate Recreation Programs § 544.30 Purpose and scope. The Bureau of Prisons encourages inmates to make constructive use of leisure time and offers movies, games, sports, social activities, arts and...

  8. 50 CFR 230.1 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF COMMERCE WHALING WHALING PROVISIONS § 230.1 Purpose and scope. The purpose of the regulations in this part is to implement the Whaling Convention Act (16 U.S.C. 916 et seq.) by prohibiting whaling except for aboriginal subsistence whaling allowed by the International Whaling...

  9. 41 CFR 101-31.000 - Scope of part.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of part. 101-31.000 Section 101-31.000 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 31-INSPECTION AND QUALITY CONTROL §...

  10. Scope and precision of sustainability assessment approaches to food systems

    Directory of Open Access Journals (Sweden)

    Christian Schader

    2014-09-01

    Full Text Available With sustainability within food systems becoming an increasingly important issue, several approaches that claim to assess the sustainability of farms, farming systems, and supply chains have been developed. Looking more closely at these sustainability impact assessment approaches, we discerned considerable differences between them in terms of scope, the level of assessment, and the precision of indicators used for impact assessment. Our aim was to classify and analyze a range of available sustainability impact assessment approaches with respect to scope and precision. From a total of 35 sustainability assessment approaches, we selected 6 for a detailed comparison. From our analysis, we concluded that there are 3 different types of trade-offs in these approaches: between different kinds of scope, between different indicators for precision and trade-offs, and between the scope and precision. Thus, one-size-fits-all solutions, with respect to tool selection, are rarely feasible. Furthermore, as indicator selection determines the assessment results, different and inconsistent indicators can lead to contradictory assessment results that may not be comparable. To overcome these shortcomings, sustainability impact assessments should include a precise definition of the notion of “sustainability” along with a description of the methodological approach and the indicator sets and should aim for harmonization of indicators and assumptions. Global initiatives such as the Sustainability Assessment in Food and Agriculture Systems (SAFA Guidelines are a helpful step toward shedding light on the differences of these approaches and making the assessment results more comparable.

  11. 42 CFR 416.61 - Scope of facility services.

    Science.gov (United States)

    2010-10-01

    ... (CONTINUED) MEDICARE PROGRAM AMBULATORY SURGICAL SERVICES Scope of Benefits for Services Furnished Before... are not limited to— (1) Nursing, technician, and related services; (2) Use of the facilities where the surgical procedures are performed; (3) Drugs, biologicals, surgical dressings, supplies, splints,...

  12. 42 CFR 416.164 - Scope of ASC services.

    Science.gov (United States)

    2010-10-01

    ... surgical procedure under § 416.166 include, but are not limited to— (1) Nursing, technician, and related services; (2) Use of the facility where the surgical procedures are performed; (3) Any laboratory testing... (CONTINUED) MEDICARE PROGRAM AMBULATORY SURGICAL SERVICES Coverage, Scope of ASC Services, and...

  13. Agricultural pricing policy in Kenya : scope and impact

    NARCIS (Netherlands)

    Meilink, H.A.

    1985-01-01

    Reviews the findings of available studies and reports thought to be of relevance to policy makers. A discussion of the institutional framework, of criteria used in price-setting procedures, and of scope and objectives of the agricultural pricing policies is folowed by an examination of what these po

  14. Air Conditioning, Heating, and Refrigeration: Scope and Sequence.

    Science.gov (United States)

    Nashville - Davidson County Metropolitan Public Schools, TN.

    This scope and sequence guide, developed for an air conditioning, heating, and refrigeration vocational education program, represents an initial step in the development of a systemwide articulated curriculum sequence for all vocational programs within the Metropolitan Nashville Public School System. It was developed as a result of needs expressed…

  15. 41 CFR 101-6.500 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of subpart. 101-6.500 Section 101-6.500 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 6-MISCELLANEOUS REGULATIONS 6.5-Code of Ethics...

  16. 48 CFR 370.400 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... SPECIAL PROGRAMS AFFECTING ACQUISITION Acquisitions Involving the Use of Laboratory Animals 370.400 Scope of subpart. This subpart applies to all R & D, research training, biological testing, housing and maintenance, and other activities involving live vertebrate animals conducted under contract (see...

  17. 48 CFR 915.200 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt of Proposals and Information 915.200 Scope of subpart. The 48 CFR subpart 15.2 is not applicable to Program Opportunity Notices for Commercial Demonstrations (See subpart 917.72) or Program Research and Development Announcements (See...

  18. 11 CFR 9420.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Purpose and scope. 9420.1 Section 9420.1 Federal Elections ELECTION ASSISTANCE COMMISSION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... on the basis of handicap in programs or activities conducted by the Commission....

  19. 10 CFR 820.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... and facilities covered under E.O. 12344, 42 U.S.C. 7158 note, pertaining to Naval nuclear propulsion... exemptions related to this part. The Deputy Administrator for Naval Reactors or his designee will be... OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.1 Purpose and scope. (a)...

  20. Circuit: the μSCOPE: A poor man's oscilloscope

    NARCIS (Netherlands)

    Dekker, R.

    2008-01-01

    The oscilloscope is still one of the most important measurement tools of the electronic engineer. With the advent of the often very reasonably priced USB scopes, such an instrument is now within reach of everybody. Twentyfive years ago that was quite a different story. A (good) oscilloscope was then

  1. 28 CFR 550.30 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 550.30 Section 550.30 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT DRUG PROGRAMS..., such as those involved in community activities, those with a history of drug use, and those...

  2. 28 CFR 105.10 - Definitions, purpose, and scope.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Definitions, purpose, and scope. 105.10 Section 105.10 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIMINAL HISTORY BACKGROUND... subject to Federal Aviation Administration (FAA) regulation. Accordingly, these entities, when...

  3. 47 CFR 1.3000 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... CFR part 2635. Travel, subsistence and related expenses for non-government-sponsored meetings or... 31 U.S.C. 1353, and its General Services Administration's implementing regulations, 41 CFR 304-1.8... 47 Telecommunication 1 2010-10-01 2010-10-01 false Purpose and scope. 1.3000 Section...

  4. 40 CFR 264.1 - Purpose, scope and applicability.

    Science.gov (United States)

    2010-07-01

    ... General § 264.1 Purpose, scope and applicability. (a) The purpose of this part is to establish minimum national standards which define the acceptable management of hazardous waste. (b) The standards in this... facility permitted, licensed, or registered by a State to manage municipal or industrial solid waste,...

  5. 20 CFR 655.0 - Scope and purpose of part.

    Science.gov (United States)

    2010-04-01

    .... worker is available to fill the job opportunity, and unless the employment of the foreign worker in the... EMPLOYMENT OF FOREIGN WORKERS IN THE UNITED STATES § 655.0 Scope and purpose of part. (a) Subparts A, B, and... nonimmigrant foreign workers, and (ii) whether the employment of aliens for such temporary work will...

  6. 18 CFR 385.402 - Scope of discovery (Rule 402).

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Scope of discovery (Rule 402). 385.402 Section 385.402 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... legal theories of an attorney. (c) Expert testimony. Unless otherwise restricted by the...

  7. 9 CFR 149.0 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Purpose and scope. 149.0 Section 149.0 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... slaughter facilities and other persons that handle or process swine from pork production sites that...

  8. 41 CFR 128-1.5001 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... Justice as they pertain to personal property management functions. ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 128-1.5001 Section 128-1.5001 Public Contracts and Property Management Federal Property...

  9. 49 CFR 365.501 - Scope of rules.

    Science.gov (United States)

    2010-10-01

    ... APPLICATIONS FOR OPERATING AUTHORITY Special Rules for Certain Mexico-domiciled Carriers § 365.501 Scope of rules. (a) The rules in this subpart govern the application by a Mexico-domiciled motor carrier to provide transportation of property or passengers in interstate commerce between Mexico and points in...

  10. 28 CFR 80.13 - Scope of FCPA Opinion.

    Science.gov (United States)

    2010-07-01

    ... Justice's views on the legal or factual issues that may be raised before that agency, or in an appeal from... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Scope of FCPA Opinion. 80.13 Section 80.13 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FOREIGN CORRUPT PRACTICES ACT...

  11. 16 CFR 1750.3 - Scope and application.

    Science.gov (United States)

    2010-01-01

    ... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION REFRIGERATOR SAFETY ACT REGULATIONS STANDARD FOR DEVICES TO PERMIT THE OPENING OF HOUSEHOLD REFRIGERATOR DOORS FROM THE INSIDE § 1750.3 Scope and application. This standard shall apply to devices furnished with household refrigerators manufactured...

  12. 28 CFR 545.20 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... COMPENSATION Inmate Work and Performance Pay Program § 545.20 Purpose and scope. (a) The Bureau of Prisons... all or part of the work program. (b) The Warden may recognize an inmate's work performance or productive participation in specified correctional programs by granting performance pay....

  13. 41 CFR 101-6.2100 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of subpart. 101-6.2100 Section 101-6.2100 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 6-MISCELLANEOUS REGULATIONS...

  14. 28 CFR 544.100 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... EDUCATION Inmate Library Services § 544.100 Purpose and scope. The Bureau of Prisons provides inmates within each of its institutions with library services necessary for educational, cultural, and leisure activity. The Warden shall ensure that the inmate library has a wide variety of reading materials....

  15. 12 CFR 1731.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... DEVELOPMENT SAFETY AND SOUNDNESS MORTGAGE FRAUD REPORTING § 1731.1 Purpose and scope. The purpose of this section is to set forth safety and soundness requirements with respect to the reporting of mortgage fraud... Financial Safety and Soundness Act of 1992 (12 U.S.C. 4501 et seq.)....

  16. 14 CFR 437.7 - Scope of an experimental permit.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Scope of an experimental permit. 437.7 Section 437.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... following criteria: (i) Is closely proximate in time to flight, (ii) Entails critical steps preparatory...

  17. 29 CFR 4071.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Purpose and scope. 4071.1 Section 4071.1 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION ENFORCEMENT PROVISIONS PENALTIES FOR... adjusted to account for inflation pursuant to the Federal Civil Monetary Penalty Inflation Adjustment...

  18. 29 CFR 4302.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Purpose and scope. 4302.1 Section 4302.1 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION MULTIEMPLOYER ENFORCEMENT PROVISIONS... to account for inflation pursuant to the Federal Civil Monetary Penalty Inflation Adjustment Act...

  19. 27 CFR 555.1 - Scope of regulations.

    Science.gov (United States)

    2010-04-01

    ... EXPLOSIVES, DEPARTMENT OF JUSTICE EXPLOSIVES COMMERCE IN EXPLOSIVES Introduction § 555.1 Scope of regulations... Pub. L. 107-296 (116 Stat. 2135). (b) Procedural and substantive requirements. This part contains the procedural and substantive requirements relative to: (1) The interstate or foreign commerce in...

  20. 5 CFR 9901.104 - Scope of authority.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Scope of authority. 9901.104 Section 9901.104 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS... with performance appraisal systems; (b) Chapter 51, dealing with General Schedule job...

  1. 48 CFR 904.7100 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... MATTERS Prohibition on Contracting (National Security Program Contracts) 904.7100 Scope of subpart. This subpart implements section 836 of the Fiscal Year 1993 Defense Authorization Act (Pub. L. 102-484) which prohibits the award of a Department of Energy contract under the national security program to an...

  2. 12 CFR 25.61 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... of 1994 (Interstate Act). (b) Scope. (1) This subpart applies to any national bank that has operated... and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY COMMUNITY REINVESTMENT ACT AND INTERSTATE DEPOSIT PRODUCTION REGULATIONS Regulations Prohibition Against Use of Interstate...

  3. 22 CFR 211.1 - General purpose and scope; legislation.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false General purpose and scope; legislation. 211.1...; legislation. (a) Legislation. The Agricultural Trade Development and Assistance Act of 1954, as amended (Pub...-624, 104 Stat. 3632-65 (1990). The legislation implemented by the regulation in this part (as of...

  4. 7 CFR 623.1 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... persons owning croplands that were damaged by the 1993 Midwest floods if those lands have the potential... Midwest floods of 1993. As more fully defined and described in this part, eligible land may include farmed... 7 Agriculture 6 2010-01-01 2010-01-01 false Purpose and scope. 623.1 Section 623.1...

  5. 36 CFR 251.80 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... scope. (a) This subpart provides a process by which those who hold or, in certain instances, those who apply for written authorizations to occupy and use National Forest System lands, may appeal a written...) The rules in this subpart seek to offer appellants a fair and deliberate process for appealing...

  6. 42 CFR 424.70 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... violates the conditions to which it agreed in accepting assignment from the individual; and (3) Specifies...) MEDICARE PROGRAM CONDITIONS FOR MEDICARE PAYMENT Limitations on Assignment and Reassignment of Claims § 424... services or a beneficiary. (b) Scope. This subpart— (1) Prohibits the assignment, reassignment, or...

  7. 40 CFR 725.400 - Scope and purpose.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Scope and purpose. 725.400 Section 725.400 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... review under this part are listed in § 725.420. (c) Criteria for the introduced genetic...

  8. 32 CFR 185.2 - Applicability and scope.

    Science.gov (United States)

    2010-07-01

    ... military support to civil law enforcement. (See § 185.4(b).) ... National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE MILITARY SUPPORT TO CIVIL AUTHORITIES (MSCA) § 185.2 Applicability and scope. This part: (a) Applies to the Office of...

  9. 41 CFR 60-50.1 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... 50-GUIDELINES ON DISCRIMINATION BECAUSE OF RELIGION OR NATIONAL ORIGIN § 60-50.1 Purpose and scope... performing under federally assisted construction contracts, without regard to religion or national origin. (b... religion and/or national origin. These guidelines are intended to remedy such unfair treatment. (c)...

  10. 31 CFR 10.0 - Scope of part.

    Science.gov (United States)

    2010-07-01

    ... Money and Finance: Treasury Office of the Secretary of the Treasury PRACTICE BEFORE THE INTERNAL REVENUE SERVICE § 10.0 Scope of part. This part contains rules governing the recognition of attorneys, certified public accountants, enrolled agents, and other persons representing clients before the Internal...

  11. Understanding, scoping and defining user experience: A survey approach

    NARCIS (Netherlands)

    Law, E.L.C.; Roto, V.; Hassenzahl, M.; Vermeeren, A.P.O.S.; Kort, J.

    2009-01-01

    Despite the growing interest in user experience (UX), it has been hard to gain a common agreement on the nature and scope of UX. In this paper, we report a survey that gathered the views on UX of 275 researchers and practitioners from academia and industry. Most respondents agree that UX is dynamic,

  12. 36 CFR 1290.1 - Scope of assassination record.

    Science.gov (United States)

    2010-07-01

    ... JFK ASSASSINATION RECORDS GUIDANCE FOR INTERPRETATION AND IMPLEMENTATION OF THE PRESIDENT JOHN F. KENNEDY ASSASSINATION RECORDS COLLECTION ACT OF 1992 (JFK ACT) § 1290.1 Scope of assassination record. (a... limitation: (1) All records as defined in Section 3(2) of the JFK Act; (2) All records collected by...

  13. 29 CFR 2570.96 - Scope of discovery.

    Science.gov (United States)

    2010-07-01

    ... section shall apply in lieu of 29 CFR 18.14. (a) A party may file a motion to conduct discovery with the... 29 Labor 9 2010-07-01 2010-07-01 false Scope of discovery. 2570.96 Section 2570.96 Labor... ADMINISTRATION AND ENFORCEMENT UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 PROCEDURAL...

  14. Planning of tests and procedures and determination of sampling scope

    International Nuclear Information System (INIS)

    The paper relies on available information showing the contents of natural uranium and thorium in the human organism and explains for the example of Th-232 in human faeces the scope of sampling activities required in order to derive reliable information with the intended accuracy. (orig./CB)

  15. 48 CFR 853.300 - Scope of subpart.

    Science.gov (United States)

    2010-10-01

    ... FORMS Illustration of Forms 853.300 Scope of subpart. VA Forms will not be illustrated in this VAAR. Persons wishing to obtain copies of VA forms prescribed in the VAAR may do so in accordance with 853.107. VA forms may also be available on the Web at http://www.va.gov/vaforms/....

  16. 28 CFR 544.40 - Purpose and scope.

    Science.gov (United States)

    2010-07-01

    ... Mandatory English-as-a-Second Language Program (ESL) § 544.40 Purpose and scope. Pursuant to the Crime Control Act of 1990 (18 U.S.C. 3624(f)), limited English proficient inmates confined in Federal Bureau of Prisons institutions are required to attend an English-as-a-Second Language (ESL) program until...

  17. 20 CFR 416.901 - Scope of subpart.

    Science.gov (United States)

    2010-04-01

    ... in telling us of any events that may cause a change in your disability or blindness status and when... DISABLED Determining Disability and Blindness General § 416.901 Scope of subpart. In order for you to become entitled to any benefits based upon disability or blindness you must be disabled or blind...

  18. Scoping of flood hazard mapping needs for Cumberland County, Maine

    Science.gov (United States)

    Dudley, Robert W.; Schalk, Charles W.

    2006-01-01

    This report was prepared by the U.S. Geological Survey (USGS) Maine Water Science Center as the deliverable for scoping of flood hazard mapping needs for Cumberland County, Maine, under Federal Emergency Management Agency (FEMA) Inter-Agency Agreement Number HSFE01-05-X-0018. This section of the report explains the objective of the task and the purpose of the report. The Federal Emergency Management Agency (FEMA) developed a plan in 1997 to modernize the FEMA flood mapping program. FEMA flood maps delineate flood hazard areas in support of the National Flood Insurance Program (NFIP). FEMA's plan outlined the steps necessary to update FEMA's flood maps for the nation to a seamless digital format and streamline FEMA's operations in raising public awareness of the importance of the maps and responding to requests to revise them. The modernization of flood maps involves conversion of existing information to digital format and integration of improved flood hazard data as needed. To determine flood mapping modernization needs, FEMA has established specific scoping activities to be done on a county-by-county basis for identifying and prioritizing requisite flood-mapping activities for map modernization. The U.S. Geological Survey (USGS), in cooperation with FEMA and the Maine State Planning Office Floodplain Management Program, began scoping work in 2005 for Cumberland County. Scoping activities included assembling existing data and map needs information for communities in Cumberland County, documentation of data, contacts, community meetings, and prioritized mapping needs in a final scoping report (this document), and updating the Mapping Needs Update Support System (MNUSS) Database or its successor with information gathered during the scoping process. The average age of the FEMA floodplain maps in Cumberland County, Maine is 21 years. Most of these studies were in the early to mid 1980s. However, in the ensuing 20-25 years, development has occurred in many of the

  19. Isotope Production Facility Conceptual Thermal-Hydraulic Design Review and Scoping Calculations

    Energy Technology Data Exchange (ETDEWEB)

    Pasamehmetoglu, K.O.; Shelton, J.D.

    1998-08-01

    The thermal-hydraulic design of the target for the Isotope Production Facility (IPF) is reviewed. In support of the technical review, scoping calculations are performed. The results of the review and scoping calculations are presented in this report.

  20. EarthScope Content Module for IRIS Active Earth Monitor

    Science.gov (United States)

    McQuillan, P. J.; Welti, R.; Johnson, J. A.; Shiffman, C. R.; Olds, S. E.

    2012-12-01

    The Active Earth Monitor (AEM) is an interactive computer-based display for university lobbies, museums, visitor centers, schools and libraries. AEM runs in a standard Internet web browser in full screen mode. The display consists of a customizable set of content pages about plate tectonics, earthquakes, volcanoes and tsunamis. Low-cost and simple-to-implement, the Active Earth Monitor provides a way to engage audiences with earth science information without spending resources on a large exhibit. The EarthScope Active Earth Monitor content set highlights the connections between the landscape and the research and monitoring being conducted by EarthScope in partnership with regional monitoring networks. Modules consist of chapters that focus on What is EarthScope?, EarthScope Observatories, and EarthScope Research Results. Content topics are easily explored using a web page button type navigation interface via a touch screen or mouse. A formative evaluation of general public users informed the interface design. Chapters in the modules start with a general overview and proceed to detailed specifics. Each chapter utilizes at least one set of live or near real-time research data (often more than one). This exposes the general public to active ongoing research that is engaging, relevant to the individual user, and explained in easy to understand terms. All live content is updated each time a user accesses the individual page displaying the live data. Leading questions are presented allowing the user to examine the content before accessing the answer via pop-up box. Diagrams and charts of research data have explanatory keys that allow users to self explore all content. Content pages can be created and inserted in the Active Earth Monitor by utilizing the simple HTML/CSS coding.;

  1. Focusing the EarthScope for a Broader Audience

    Science.gov (United States)

    Smith-Konter, B. R.

    2011-12-01

    One of the most challenging milestones of scientific research is often the translation of a technical result into a clear "teachable moment" that is accessible (and interesting!) to a broader audience. The success of this milestone can largely be measured by its effectiveness to inspire interest and enthusiasm in the non-scientist. Moreover, as 4D multimedia now dominates most aspects of our social environment, science "teaching" now also requires intervention of visualization technology and animation to portray research results in an inviting and stimulating manner. In response to these needs, a primary objective of the EarthScope Education and Outreach program is to transform technical science into teachable products for a technologically thriving generation. Following the Incorporated Research Institutions for Seismology (IRIS)'s lead in developing interactive Earth science kiosk multimedia (bundled in a free product called Active Earth), a major focus of this EarthScope CAREER project is aimed at the construction and installation of customized EarthScope-themed touch screen kiosks in local communities. These kiosks are helping to educate a broader audience about EarthScope's unique instrumentation and observations using interactive animations, games, and virtual field trips. An additional focus of this CAREER project is aimed at the development of several Earthquakes in Action teaching modules for grades 6-12, which have been successfully tested and implemented in both teacher-prep courses and an annual high school summer geosciences camp at the University of Texas at El Paso. These activities are beginning to shape a new pathway for how teachers teach and students learn about planet Earth and its fantastic EarthScope - one click (and touch) at a time.

  2. Financial Integration and Economies of Scope: A Cross-Industry Analysis of Bancassurance in Taiwan

    OpenAIRE

    Lih Ru Chen; Jin Lung Peng; Jennifer L Wang

    2008-01-01

    Using unique bancassurance data from Taiwan, we examine whether banks improve their scope economies by engaging in bancassurance activities. We adopt an econometric approach to identify the relation between economies of scope and bancassurance. The empirical results show that higher involvement in bancassurance helps banks improve their cost scope economies but may also lead to revenue scope diseconomies. However, the overall results indicate that banks in Taiwan realized greater gains from c...

  3. A cost analysis of reusable and disposable flexible optical scopes for intubation

    DEFF Research Database (Denmark)

    Tvede, M F; Kristensen, M S; Nyhus-Andreasen, M

    2012-01-01

    Intubation using a flexible optical scope (FOS) is a cornerstone technique for managing the predicted and unpredicted difficult airway. The term FOS covers both fibre-optic scopes and videoscopes. The total costs of using flexible scopes for intubation are unknown. The recent introduction of a di...

  4. 14 CFR 1260.25 - Change in principal investigator or scope.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Change in principal investigator or scope... COOPERATIVE AGREEMENTS General Provisions § 1260.25 Change in principal investigator or scope. Change in Principal Investigator or Scope October 2000 The following guidance is provided as an amplification to...

  5. Defining the Scope of Grievance Arbitration in Public Education Employment Contracts

    Science.gov (United States)

    Shipley, David E.

    1974-01-01

    After examining the case law in this area, the comment concludes that the scope of grievance arbitration should be coextensive with the scope of collective bargaining. This broad scope of grievance arbitration can be achieved without destroying a school board's ability to manage its schools. (Author)

  6. 15 CFR 732.2 - Steps regarding scope of the EAR.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Steps regarding scope of the EAR. 732... FOR USING THE EAR § 732.2 Steps regarding scope of the EAR. Steps 1 though 6 are designed to aid you in determining the scope of the EAR. A flow chart describing these steps is contained in...

  7. Full-scope nuclear training simulator -brought to the desktop

    International Nuclear Information System (INIS)

    RighTSTEP is a suite of simulation software which has been initially designed to facilitate upgrade of Ontario Hydro's full-scope simulators, but is also adaptable to a variety of other roles. it is presently being commissioned at Bruch A Training Simulator and has seen preliminary use in desktop and classroom roles. Because of the flexibility of the system, we anticipate it will see common use in the corporation for full-scope simulation roles. A key reason for developing RighTSTEP (Real Time Simulator Technology Extensible and Portable) was the need to modernize and upgrade the full-scope training simulator while protecting the investment in modelling code. This modelling code represents the end product of 18 years of evolution from the beginning of its development in 1979. Bringing this modelling code to a modern and more useful framework - the combination of simulator host, operating system, and simulator operating system - also could provide many spin-off benefits. The development (and first implementation) of the righTSTEP system was cited for saving the corporation 5.6M$ and was recognized by a corporate New Technology Award last year. The most important spin-off from this project has been the desktop version of the full-scope simulator. The desktop simulator uses essentially the same software as does its full-scope counterpart, and may be used for a variety of new purposes. Classroom and individual simulator training can now be easily accommodated since a desktop simulator is both affordable and relatively ease to use. Further, a wide group of people can be trained using the desktop simulator: by contrast the full-scope simulators were almost exclusively devoted to front-line operating staff. The desktop is finding increasing use in support of engineering applications, resulting from its easy accessibility, breadth of station systems represented, and tools for analysis and viewing. As further plant models are made available on the new simulator platform and

  8. Earthquake warning system for infrastructures : a scoping analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, Nancy S.; O' Connor, Sharon L.; Stamber, Kevin Louis; Kelic, Andjelka; Fogleman, William E. (GRIT, Inc., Albuquerque, NM); Vugrin, Eric D.; Corbet, Thomas Frank, Jr.; Brown, Theresa Jean

    2011-09-01

    This report provides the results of a scoping study evaluating the potential risk reduction value of a hypothetical, earthquake early-warning system. The study was based on an analysis of the actions that could be taken to reduce risks to population and infrastructures, how much time would be required to take each action and the potential consequences of false alarms given the nature of the action. The results of the scoping analysis indicate that risks could be reduced through improving existing event notification systems and individual responses to the notification; and production and utilization of more detailed risk maps for local planning. Detailed maps and training programs, based on existing knowledge of geologic conditions and processes, would reduce uncertainty in the consequence portion of the risk analysis. Uncertainties in the timing, magnitude and location of earthquakes and the potential impacts of false alarms will present major challenges to the value of an early-warning system.

  9. Immigration and its impact on daily occupations: a scoping review.

    Science.gov (United States)

    Bennett, Kayla Marie; Scornaiencki, Jennifer Marie; Brzozowski, Jennifer; Denis, Suzanne; Magalhaes, Lilian

    2012-12-01

    Immigrants often adopt new and unfamiliar occupations in an attempt to adapt to their new culture. Occupations provide a means for participation in the host country and play a significant role in formulating a person's identity. This scoping review sought to identify the current knowledge on immigration and its impact on occupations. A scoping review for peer-reviewed articles published between 2000 and 2010 in English or French was completed. Thirty-six articles met the inclusion criteria. Four themes were identified: 1) role change; 2) work; 3) identity; and 4) health and well-being. Limitations include the lack of a consistent definition of occupation, research primarily being conducted in the North American context and the limited number of occupational therapy based articles. Future research should focus on a systematic review of the lived experiences of immigrants and their occupational contexts, and how this can inform policy development.

  10. Mindfulness Interventions in Physical Rehabilitation: A Scoping Review.

    Science.gov (United States)

    Hardison, Mark E; Roll, Shawn C

    2016-01-01

    A scoping review was conducted to describe how mindfulness is used in physical rehabilitation, identify implications for occupational therapy practice, and guide future research on clinical mindfulness interventions. A systematic search of four literature databases produced 1,524 original abstracts, of which 16 articles were included. Although only 3 Level I or II studies were identified, the literature included suggests that mindfulness interventions are helpful for patients with musculoskeletal and chronic pain disorders and demonstrate trends toward outcome improvements for patients with neurocognitive and neuromotor disorders. Only 2 studies included an occupational therapist as the primary mindfulness provider, but all mindfulness interventions in the selected studies fit within the occupational therapy scope of practice according to the American Occupational Therapy Association's Occupational Therapy Practice Framework: Domain and Process. Higher-level research is needed to evaluate the effects of mindfulness interventions in physical rehabilitation and to determine best practices for the use of mindfulness by occupational therapy practitioners.

  11. The Scope and Structure of the General EU Budget

    Directory of Open Access Journals (Sweden)

    Małgorzata Cilak

    2014-06-01

    Full Text Available The purpose of this article is to present the scope and structure of the general budget of the European Union. EU general budget is constructed in accordance with the budgetary principles that are set out in Regulation No 966/2012. The scope of the budget is related to entities whose income and expenses are accounted for in the budget. It is connected with the principle of unity and budget accuracy. The structure and content of the budget, however, are associated with the data exhibited in the budget and the way they are presented. Of particular importance in the context of the structure and content of the budget are principles such as universality, balance, specification.

  12. Ethical reasons for narrowing the scope of biotech patents.

    Science.gov (United States)

    Andreassen, Tom

    2015-11-01

    Patents on biotech products have a scope that goes well beyond what is covered by the most widely applied ethical justifications of intellectual property. Neither natural rights theory from Locke, nor public interest theory of IP rights justifies the wide scope of legal protection. The article takes human genes as an example, focusing on the component that is not invented but persists as unaltered gene information even in the synthetically produced complementary DNA, the cDNA. It is argued that patent on cDNA holds this information captive, or illegitimately appropriates it in limiting other researchers and inventors' opportunity to explore new functions and uses based on this non-invented information. A tighter connection between legal IP protection and the use description stated in the patent claim is suggested. By binding protection to the product's foreseeable functions and use, instead of the product itself and all future uses of it, legitimacy of biotech product patents is restored.

  13. Scope of Internal Marketing in B2B Companies

    OpenAIRE

    Nigam, Niharika

    2007-01-01

    Abstract Previous studies have focused on "internal marketing" from services marketing perspective. There is, therefore, a great dearth of in-depth research on its application to other business types. This research attempts to find the scope of internal marketing in B2B companies. The purpose of this research is to closely examine the elements, their linkage, tools and applications of Internal marketing when applied to B2B settings. Internal marketing, the application of marketing managem...

  14. 10 CFR 2.1000 - Scope of subpart J.

    Science.gov (United States)

    2010-01-01

    ... over those in 10 CFR part 2, subpart C, except for the following provisions: §§ 2.301; 2.303; 2.307; 2...; 2.348; and 2.390. The procedures in this subpart take precedence over those in 10 CFR part 2... 10 Energy 1 2010-01-01 2010-01-01 false Scope of subpart J. 2.1000 Section 2.1000 Energy...

  15. A scoping review of definitions and frameworks of intersectoral action

    OpenAIRE

    Alejandra Dubois; Louise St-Pierre; Mirella Veras

    2015-01-01

    AbstractIntersectoral action is rooted in all health promotion activities because the determinants of health lie outside of the health sector. Despite the increasing use of these terms (intersectoral action, intersectoral action for health, intersectoral collaboration), often interchangeably, we noted a lack of consensus on their definitions and conceptualizations. The objective of this paper is to report the results of a scoping review of the use of definitions for a set of related terms as ...

  16. Economies of scale and scope in Vietnamese hospitals.

    Science.gov (United States)

    Weaver, Marcia; Deolalikar, Anil

    2004-07-01

    Hospitals consume a large share of health resources in developing countries, but little is known about the efficiency of their scale and scope. The Ministry of Health of Vietnam and World Bank collected data in 1996 from the largest sample ever surveyed in a developing country. The sample included 654 out of 815 public hospitals, six categories of hospitals and a broad range of sizes. These data were used to estimate total variable cost as a function of multiple products, such as admissions and outpatient visits. We report results for two specifications: (1) estimates with a single variable for beds and (2) estimates with interaction terms for beds and the category of hospital. The coefficient estimates were used to calculate marginal costs, short-run returns to the variable factor, economies of scale, and economies of scope for each category of hospital. There were important differences across categories of hospitals. The measure of economies of scale was 1.09 for central general and 1.05 for central specialty hospitals with a mean of 516 and 226 beds, respectively, indicating roughly constant returns to scale. The measure was well below one for both provincial general and specialty hospitals with a mean of 357 and 192 beds, respectively, indicating large diseconomies of scale. The measure was 1.16 for district hospitals and 0.89 other ministry hospitals indicating modest economies and diseconomies of scale, respectively. There were large economies of scope for central and provincial general hospitals. We conclude that in a system of public hospitals in a developing country that followed an administrative structure, the variable cost function differed significantly across categories of hospitals. Economies of scale and scope depended on the category of the hospital in addition to the number of beds and volume of output.

  17. SCOPE: A Scientific Compound Object Publishing and Editing System

    OpenAIRE

    Kwok Cheung; Jane Hunter; Anna Lashtabeg; John Drennan

    2008-01-01

    This paper presents the SCOPE (Scientific Compound Object Publishing and Editing) system which is designed to enable scientists to easily author, publish and edit scientific compound objects. Scientific compound objects encapsulate the various datasets and resources generated or utilized during a scientific experiment or discovery process, within a single compound object, for publishing and exchange. The adoption of “named graphs” to represent these compound objects enables provenance informa...

  18. Determinants of unlawful file sharing:a scoping review

    OpenAIRE

    Steven James Watson; Daniel John Zizzo; Piers Fleming

    2015-01-01

    We employ a scoping review methodology to consider and assess the existing evidence on the determinants of unlawful file sharing (UFS) transparently and systematically. Based on the evidence, we build a simple conceptual framework to model the psychological decision to engage in UFS, purchase legally or do nothing. We identify social, moral, experiential, technical, legal and financial utility sources of the decision to purchase or to file share. They interact in complex ways. We consider the...

  19. Compassion: a scoping review of the healthcare literature

    OpenAIRE

    Sinclair, Shane; Norris, Jill M.; McConnell, Shelagh J.; Chochinov, Harvey Max; Hack, Thomas F; Hagen, Neil A.; McClement, Susan; Bouchal, Shelley Raffin

    2016-01-01

    Background Recent concerns about suboptimal patient care and a lack of compassion have prompted policymakers to question the preparedness of clinicians for the challenging environment in which they practice. Compassionate care is expected by patients and is a professional obligation of clinicians; however, little is known about the state of research on clinical compassion. The purpose of this scoping review was to map the literature on compassion in clinical healthcare. Methods Searches of ei...

  20. Angra 1 nuclear power plant full scope simulator development project

    Energy Technology Data Exchange (ETDEWEB)

    Selvatici, Edmundo; Castanheira, Luiz Carlos C.; Silva Junior, Nilo Garcia da, E-mail: edsel@eletronuclear.gov.br, E-mail: lccast@eletronuclear.gov.br, E-mail: nilogar@eletronuclear.gov.br [Eletrobras Termonuclear S.A. (SCO/ELETRONUCLEAR), Angra dos Reis, RJ (Brazil). Superintendencia de Coordenacao da Operacao; Zazo, Francisco Javier Lopez; Ruiz, Jose Antonio, E-mail: jlopez@tecnatom.es, E-mail: jaruiz@tecnatom.es [Tecnatom S.A., San Sebastian de los Reyes, Madrid (Spain)

    2015-07-01

    Specific Full Scope Simulators are an essential tool for training NPP control room operators, in the formation phase as well as for maintaining their qualifications. In the last years availability of a Plant specific simulator has also become a Regulator requirement for Nuclear Power Plant operation. By providing real-time practical training for the operators, the use of a simulator allows improving the operator's performance, reducing the number of unplanned shutdowns and more effective response to abnormal and emergency operating conditions. It can also be used, among other uses, to validate procedures, test proposed plant modifications, perform engineering studies and to provide operation training for the technical support staff of the plant. The NPP site, in Angra dos Reis-RJ, Brazil, comprises the two units in operation, Unit 1, 640 MWe, Westinghouse PWR and Unit 2, 1350 MWe, KWU/Areva PWR and one unit in construction, Unit 3, 1405 MWe, KWU/Areva PWR, of the same design of Angra 2. Angra 2 has had its full scope simulator from the beginning, however this was not the case of Angra 1, that had to train its operators abroad, due to lack of a specific simulator. Eletronuclear participated in all the phases of the project, from data supply to commissioning and validation. The Angra 1 full scope simulator encompasses more than 80 systems of the plant including the Primary system, reactor core and associated auxiliary systems, the secondary system and turbo generator as well as all the Plant operational and safety I and C. The Angra 1 Main Control Room panels were reproduced in the simulator control room as well as the remote shutdown panels that are outside the control room. This paper describes the project for development of the Angra 1 NPP Full Scope Simulator, supplied by Tecnatom S.A., in the period of Feb.2012 to Feb.2015. (author)