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Sample records for 3m cavilon sobre

  1. Evaluación in vivo mediante microscopia confocal del efecto protector de la película barrera no irritante 3M Cavilon sobre la piel perilesional In vivo evaluation using confocal microscopy of protective effect of no-sting barrier film 3M Cavilon on periwound skin

    Directory of Open Access Journals (Sweden)

    Teresa Segovia Gómez

    2008-03-01

    Full Text Available Tradicionalmente, el manejo de las úlceras cutáneas incluye medidas que facilitan la cicatrización, tales como el buen desbridamiento, ya sea médico o quirúrgico, apósitos oclusivos, tratamiento de infección y buena nutrición; sin embargo, es importante la valoración y el tratamiento de la piel perilesional. En este sentido, recientemente, diversos autores han descrito la coexistencia de trastornos nutricionales y tróficos en la misma, muchos de ellos de causa iatrogénica, y donde el uso de la película barrera no irritante 3M Cavilon puede ser un pilar importante para una buena respuesta al tratamiento. Los objetivos que se persiguen con el presente estudio pretenden identificar las características confocales de la piel perilesional de las úlceras venosas y evaluar los cambios dinámicos que experimenta la misma tras el uso adyuvante de la película barrera no irritante 3M Cavilon en su tratamiento. Para ello, pacientes afectos con úlceras venosas de larga evolución fueron tratados durante una semana de manera convencional utilizando, además del material de cura, 3M Cavilon en una sección de la piel perilesional. La zona de piel perilesional en la que no se utilizó 3M Cavilon nos sirvió como control. Las úlceras fueron evaluadas por inspección visual, fotografía digital y microscopía confocal in vivo previa al uso de 3M Cavilon y a la semana de aplicación diaria del producto. Las úlceras demostraron una mejoría clínica. La evaluación con microscopía confocal de reflectancia evidenció importante mejoría histológica del área tratada con 3M Cavilon comparada con el área no tratada con este apósito. En el momento inicial del estudio, la piel perilesional demostró la presencia de áreas de necrosis epidérmicas, espongiosis, infiltración por células inflamatorias y vasodilatación prominente. Tras la semana de tratamiento, aunque todo el área de piel perilesional demostró mejoría, en el área tratada con 3M

  2. Efectividad del tratamiento de las úlceras venosas con vendaje compresivo multicapa asociado a protección de la piel perilesional con Cavilon® (película barrera no irritante Effectiveness of the association of multilayer compression therapy and periwound protection with Cavilon® (no sting barrier film in the treatment of venous leg ulcers

    Directory of Open Access Journals (Sweden)

    N. Serra

    2010-09-01

    Full Text Available Introducción: el adecuado tratamiento de las úlceras de extremidad inferior de etiología venosa es fundamental para mejorar la calidad de vida de los pacientes. El uso de terapia compresiva con vendaje multicapa es el tratamiento que mejores resultados presenta. En la práctica, se utiliza en combinación con unos adecuados cuidados locales de la herida y de la piel perilesional. El objetivo del estudio fue evaluar la efectividad clínica de un vendaje multicapa de compresión y el impacto de la utilización de la película barrera Cavilon® en úlceras vasculares de origen venoso. Metodología: ensayo clínico controlado, aleatorizado, abierto, multicéntrico y pragmático en España. Todos los pacientes incluidos fueron tratados con terapia de compresión con el mismo vendaje multicapa y asignados aleatoriamente al grupo de intervención, tratados con la PBNI Cavilon®, o al grupo control. Se realizaron un máximo de 13 visitas de estudio separadas entre ellas por una semana. El estudio fue evaluado y aprobado por los comités éticos de investigación clínica (CEIC de los siete centros participantes. Resultados: participaron 98 pacientes en el estudio (49 en el grupo intervención y 49 como control. Tras cuatro semanas, el grupo intervención presentó una reducción media (DE del tamaño de úlcera superior al grupo control (56,7% (30,3 vs. 45,5% (47,4; p = 0,087. A las 12 semanas de tratamiento, las diferencias observadas fueron estadísticamente significativas (83,4% (31,1 vs. 71,6% (44,1; p = 0,046. El 69,4% de los pacientes del grupo intervención redujo el área de úlcera en > 50% en las cuatro primeras semanas de tratamiento, respecto al 46,9% de los pacientes del grupo control (p Aim: appropriate treatment of venous leg ulcers is essential to improve the quality of life of patients. Compression therapy using multilayer bandages show to the best clinical results. In practice, it is used in combination with a suitable local care of

  3. High Performance P3M N-body code: CUBEP3M

    CERN Document Server

    Harnois-Deraps, Joachim; Iliev, Ilian T; Merz, Hugh; Emberson, J D; Desjacques, Vincent

    2012-01-01

    This paper presents CUBEP3M, a high performance, publicly-available, cosmological N-body code and describes many utilities and extensions that have been added to the standard package, including a runtime halo finder, a non-Gaussian initial conditions generator, a tuneable accuracy, and a system of unique particle identification. CUBEP3M is fast, has a memory imprint up to three times lower than other widely used N-body codes, and has been run on up to 20,000 cores, achieving close to ideal weak scaling even at this problem size. It is well suited and has already been used for a broad number of science applications that require either large samples of non-linear realizations or very large dark matter N-body simulations, including cosmological reionization, baryonic acoustic oscillations, weak lensing or non-Gaussian statistics. We discuss the structure, the accuracy, any known systematic effects, and the scaling performance of the code and its utilities, when applicable.

  4. MISC_0_3M_CLR_2008

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset (MISC_0_3M_CLR_2008) includes truecolor ortho imagery covering an area north and south of the VT/Canadian border. VCGI extracted the imagery from a...

  5. Advancement of neutron radiography technique in JRR-3M

    Energy Technology Data Exchange (ETDEWEB)

    Matsubayashi, Masahito [Center for Neutron Science, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan)

    1999-08-01

    The JRR-3M thermal neutron radiography facility (JRR-3M TNRF) was completed in the JRR-3M of the Japan Atomic Energy Research Institute in 1991 and has been utilized as research tools for various kinds of research fields such as thermal hydraulic researches, agricultural researches, medical researches, archaeological researches and so on. High performance of the JRR-3M TNRF such as high neutron flux, high collimator ratio and wide radiographing field has enabled advanced researches and stimulated developments of advanced neutron radiography (NR) systems for higher spatial resolution and for higher temporal resolution. Static NR systems using neutron imaging plates or cooled CCD camera with high spatial resolution, a real-time NR system using a silicon intensifier target tube camera and a high-frame-rate NR system using a combination of an image intensifier and a high speed digital video camera with high temporal resolution have been developed to fill the requirements from researchers. (author)

  6. MISC_0_3M_CLR_2009

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset (MISC_0_3M_CLR_2009)includes truecolor ortho imagery covering the Barre-Monteplier (Capital Region) of Vermont. VCGI reprojected the imagery from its...

  7. The Role of Training at 3M Company

    Science.gov (United States)

    Training and Development Journal, 1976

    1976-01-01

    The interview with L. W. Lehr, President of the U.S. Operation of the 3M Company, presents a management view of the company's training and development activities. The activities are based on behavior modification programs and organizational development approaches. (EC)

  8. Stephen Hawking bags big new 3m physics prize

    Science.gov (United States)

    Johnston, Hamish

    2013-01-01

    A massive 3m in prize money has gone to the British cosmologist Stephen Hawking for his work on black holes, quantum gravity and the early universe. The award is one of two "special fundamental physics prizes" from the Fundamental Physics Prize Foundation, which was set up earlier this year by the Russian physicist-turned-entrepreneur Yuri Milner.

  9. Strategic stories: how 3M is rewriting business planning.

    Science.gov (United States)

    Shaw, G; Brown, R; Bromiley, P

    1998-01-01

    Virtually all business plans are written as a list of bullet points. Despite the skill or knowledge of their authors, these plans usually aren't anything more than lists of "good things to do." For example: Increase sales by 10%. Reduce distribution costs by 5%. Develop a synergistic vision for traditional products. Rarely do these lists reflect deep thought or inspire commitment. Worse, they don't specify critical relationships between the points, and they can't demonstrate how the goals will be achieved. 3M executive Gordon Shaw began looking for a more coherent and compelling way to present business plans. He found it in the form of strategic stories. Telling stories was already a habit of mind at 3M. Stories about the advent of Post-it Notes and the invention of masking tape help define 3M's identity. They're part of the way people at 3M explain themselves to their customers and to one another. Shaw and his coauthors examine how business plans can be transformed into strategic narratives. By painting a picture of the market, the competition, and the strategy needed to beat the competition, these narratives can fill in the spaces around the bullet points for those who will approve and those who will implement the strategy. When people can locate themselves in the story, their sense of commitment and involvement is enhanced. By conveying a powerful impression of the process of winning, narrative plans can mobilize an entire organization.

  10. DC Leakage behavior and Conduction Mechanism in (BiFeO3)m(SrTiO3)m Superlattices

    OpenAIRE

    2008-01-01

    Leakage current behavior of (BiFeO3)m(SrTiO3)m superlattice structures was studied and analyzed at different temperatures (303-473K) in the light of various models. While bulk limited Poole-Frenkel emission was observed to dominate the leakage current in the temperature range of 303 - 383 K, the space charge limited conduction was observed up to 473 K. With a Poole-Frenkel emission type of conduction, the activation energy range of 0.06 - 0.2 eV was calculated. The physical parameters, calcul...

  11. Testing of the 3M Company Composite Conductor

    Energy Technology Data Exchange (ETDEWEB)

    Stovall, John P [ORNL; Rizy, D Tom [ORNL; Kisner, Roger A [ORNL

    2010-10-01

    The 3M Company has developed a high-temperature low-sag conductor referred to as Aluminum-Conductor Composite-Reinforced or ACCR. The conductor uses an aluminum metal matrix material to replace the steel in conventional conductors. The objective of this work is to accelerate the commercial acceptance by electric utilities of this new conductor design by testing four representative conductor classes in controlled conditions. A unique facility called the Powerline Conductor Accelerated Testing (PCAT) Facility was built at ORNL for testing overhead conductors. The PCAT has been uniquely designed for testing overhead bare transmission line conductors at high currents and temperatures after they have been installed and tensioned to the manufacturer's specifications. The ability to operate a transmission line conductor in this manner does not exist elsewhere in the United States. Four classes of ACCR cable designed by the 3M Company have been successfully test at ORNL small, medium, large and small/compact. Based on these and other manufacturer tests, the 3M Company has successfully introduced the ACCR into the commercial market and has completed over twenty installations for utility companies.

  12. 30 years of ergonomics at 3M: a case study.

    Science.gov (United States)

    Larson, N; Wick, H

    2012-01-01

    The added value of the Ergonomics Program at 3M was found to be improved employee safety, compliance with regulations and reduction of work-related illness, increases in productivity, and quality and operating efficiency. This paper describes the thirty years of existence of this program. For the first twenty years, the program objectives were to: respond to requests for assistance related to work-related musculoskeletal disorder (WMSD) concerns, raise employee awareness of MSDs and ergonomics; educate engineers in ergonomics design; and develop ergonomics teams at manufacturing locations. Since the year 2000, 3M's Ergonomics Program has been in transition from a US-centric and corporate-based technical-expertled program to a global program applying participatory ergonomics strategies within a macroergonomics framework. During that transition, the existing program requirements were revised, new methods and program tools were created, and expectations for implementation at the manufacturing locations clarified. This paper focuses on the company's manufacturing ergonomics program activities during the past ten years and includes specifics of the program's objectives, risk assessment reduction process, and ergonomics technical expertise development. The main benefit achieved throughout the company is reducing employee injury while also increasing productivity and operating efficiency.

  13. Hamline/3M Project: Liaison for Curricular Change

    Science.gov (United States)

    Rundquist, Andy

    2002-03-01

    This project was designed to catalyze curricular changes to better prepare students for the workplace. Industrial managers provided a list of 16 characteristics valued in the workplace: most were NOT related to science course content. The project formed 5 teams each including 3M professionals and students. Each team developed curricular changes in one of the 16 areas. Team goals were to improve skills in communication, data analysis, business/economics, team problem solving, and culture competency. Curricular changes realized include communication skill activities embodied in science courses and faculty communication teaching skill seminars, self learning tools in data analysis, statistics and model building, a new course developed with assistance from 3M personnel focussing on topics directly related to technological industries, high performance team problem solving training/coaching for faculty and workshops for students and faculty relative to importance of cultural competencies in the workplace, and a new course focusing on culture, team problem solving and conflict resolution in the technical workplace. Process for developing and content of curricular changes will be reported.

  14. Hamline/3M Corp. Project: Liason for Curricular Change*

    Science.gov (United States)

    Artz, Jerry L.

    2002-04-01

    This project was designed to catalyze curricular changes to better prepare students for the workplace. Industrial managers provided a list of 16 characteristics valued in the workplace; most were NOT related to science course content. The project formed 5 teams each including 3M professionals and students. Each team developed curricular changes in one of the 16 areas. Team goals were to improve skills in communication, data analysis, business/economics, team problem solving, and cultural competency. Curricular changes realized include communication skill activities embodied in science courses and faculty communication teaching skill seminars; self learning tools in data analysis, statistics and model building; a new course developed with assistance from 3M personnel focusing on topics directly related to technological industries; high performance team problem solving training/coaching for faculty; workshops for students and faculty relative to importance of cultural competencies in the workplace; and a new course focusing on culture, team problem solving and conflict resolution in the technical workplace. Process for developing and content of curricular changes will be reported. *Thanks to: NSF GOALI CHE-99010782

  15. Testing of the 3M Company ACCR Conductor

    Energy Technology Data Exchange (ETDEWEB)

    Stovall, J.P.; RIzy, D.T.; Kisner, R.A.; Deve, H.E. (3M Comp.)

    2010-09-15

    The 3M Company has developed a high-temperature low-sag conductor referred to as Aluminum- Conductor Composite-Reinforced or ACCR. The conductor uses an aluminum metal matrix material to replace the steel in conventional conductors so the core has a lower density and higher conductivity. The objective of this work is to accelerate the commercial acceptance by electric utilities of these new conductor designs by testing four representative conductor classes in controlled conditions. Overhead transmission lines use bare aluminum conductor strands wrapped around a steel core strands to transmit electricity. The typical cable is referred to as aluminum-conductor steel-reinforced (ACSR). The outer strands are aluminum, chosen for its conductivity, low weight, and low cost. The center strand is of steel for the strength required to support the weight without stretching the aluminum due to its ductility. The power density of a transmission corridor has been directly increased by increasing the voltage level. Transmission voltages have increased from 115-kV to 765- kV over the past 80 years. In the United States, further increasing the voltage level is not feasible at this point in time, so in order to further increase the power density of a transmission corridor, conductor designs that increase the current carrying capability have been examined. One of the key limiting factors in the design of a transmission line is the conductor sag which determines the clearance of the conductor above ground or underlying structures needed for electrical safety. Increasing the current carrying capability of a conductor increases the joule heating in the conductor which increases the conductor sag. A conductor designed for high-temperature and lowsag operation requires an engineered modification of the conductor materials. To make an advanced cable, the 3M Company solution has been the development of a composite conductor consisting of Nextel ceramic fibers to replace the steel core and

  16. Data of evolutionary structure change: 2UXML-2UX3M [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 2UXML-2UX3M 2UXM 2UX3 L M -----ALLSFE--------------RKYRVPGG--TLVG.../alignment> 0 2UXM L 2UX...U CA 253 VAL CA 231 GLY CA 185 GLY CA 184 2UX...3 M 2UX3M 1 2UXM L 2UXML

  17. Neurotrophin-3 mRNA expression in rat intrafusal muscle fibres after denervation and reinnervation

    NARCIS (Netherlands)

    Copray, JCVM; Brouwer, N

    1997-01-01

    We have studied the regulation of the expression of neurotrophin-3 (NT-3) mRNA in neonatal and adult rat muscle spindles after denervation and after denervation followed by reinnervation. Denervation of the intrafusal fibres did not result in an upregulation of the NT-3 mRNA expression but decreased

  18. Komunikační strategie společnosti 3M Česko

    OpenAIRE

    Koláček, Kamil

    2010-01-01

    This thesis is focused on marketing communication, specifically on PR communication of 3M Cesko company. Firstly, it provides a theoretical background of marketing, PR and media communication; and secondly, it examines current PR communication of 3M Cesko, and proposes a PR strategy for 2012 (which includes a proposition of media topics in 2012, PR communication tools, and a timeline).

  19. CRM System Using PA-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    Ajay kumar

    2010-04-01

    Full Text Available In today’s business world, Customer Relationship Management has become conventional. Inspite of the unpredictable economy, CRM is being forced into corporate budgets and is believed to be the leading and initiative factor by many companies. The custom of CRM system has become mandatory. An adequate CRM system helps in acquiring new customers and increasing the value of existing customers. Datawarehouse acts as the data resource for D3M on CRM. This paper introduces the CRM based on PA-AKD and managing relationships with customers which has become the critical competition betweenorganizations. Then the structure of CRM is described with the help of D3M, discusses the procedure to Data warehouse and the significance of D3M applied to CRM. At the end, the promoting effects of D3M to individual service are presented

  20. PEMETAAN DENSITAS LARVA AEDES BERDASARKAN 3M DAERAH ENDEMIS DAN NON ENDEMIS DBD

    OpenAIRE

    Yudin, Marhamah; Ibrahim, Erniwati; Natsir, Muh. Fajaruddin

    2016-01-01

    Demam Berdarah Dengue (DBD) merupakan suatu penyakit menular yang ditularkan melalui gigitan nyamuk Aedes aegypti. Pencegahan DBD dapat dilakukan dengan pengendalian vektor melalui pelaksanaan 3M. Penelitian ini bertujuan untuk mengetahui gambaran densitas larva Aedes berdasarkan pelaksanaan 3M di daerah endemis dan non endemis DBD Kota Makassar. Jenis penelitian yang digunakan adalah survey observasional dengan pendekatan deskriptif. Populasi adalah seluruh rumah di Kelurahan Gunung Sari seb...

  1. Pengaruh Penerapan Sistem Informasi Akuntansi Terhadap Pengambilan Keputusan Pada Politeknik Unggul LP3M Medan

    OpenAIRE

    Nasir, Miftah Faridh

    2014-01-01

    The purpose of this study was to determine how the analysis of the application of information systems in the management accounting can affect decision-making at the Polytechnic Unggul LP3M Medan and to determine the accounting information system to ensure accurate decision-making in a company. Primary data were collected by interviewing management and data documenting the Polytechnic Superior LP3M Medan. The analytical method used is descriptive. Hypothesis in this study is a significa...

  2. Manipulation of electronic structure via alteration of local orbital environment in [(SrIrO3)m,(SrTi O3)] (m =1 ,2 ,and ∞ ) superlattices

    Science.gov (United States)

    Kim, So Yeun; Kim, Choong H.; Sandilands, L. J.; Sohn, C. H.; Matsuno, J.; Takagi, H.; Kim, K. W.; Lee, Y. S.; Moon, S. J.; Noh, T. W.

    2016-12-01

    We investigated the electronic structure of [(SrIrO3)m,(SrTi O3)] (m =1 ,2 ,and ∞ ) superlattice (SL) thin films with optical spectroscopy and first principles calculations. Our optical results confirmed the existence of the Jeff= 1 /2 states in SL samples, similar to the bulk Ruddlesden-Popper series S rn+1I rnO3 n +1 iridates. Apart from this similarity, in the SL samples, we observed red shifts of the characteristic optical excitations in the Jeff= 1 /2 state and an enhancement of the low-energy spectral weight, which implies a reduction in the effective electron correlation for bands near the Fermi energy. The density functional theory plus Coulomb interactions (DFT +U ) calculations suggested that the SrTi O3 layer intervened between SrIr O3 layers in the SLs activated additional hopping channels between the Ir ions, thus increasing the bandwidth and reducing the effective strength of the correlations. This paper demonstrates that fabrication of iridium-based heterostructures can be used to finely tune electronic structures via alteration of their local orbital environments.

  3. Marketingová strategie hasících kapalin Novec firmy 3M

    OpenAIRE

    Peřina, Matěj

    2012-01-01

    This thesis is concerned with B2B market segmentation, situational analysis and proposes a markting strategy for Novec 1230 fire protection fluid marketed by 3M Česko. Firstly a marketing literature rewiev is carried out in order to uncover the most suitabe theoretical approaches to the subject at hand. Then the 3M Company and its Czech subsidiary are presented. In the methodological part there is a description of utilized methods and approaches. Data colection and analysis are executed in th...

  4. Digital signage sobre IP

    OpenAIRE

    Casademont Filella, Albert

    2012-01-01

    Projecte que versa sobre el disseny i la implementació d'un sistema de Digital Signage (Cartelleria Digital) sobre IP, creant un gestor que permeti controlar de forma remota tot un conjunt de petits dispositius connectats a pantalles que emeten continguts multimèdia com vídeos, imatges, feeds rss...

  5. Impuesto sobre la renta

    OpenAIRE

    Universitat de Barcelona. Grup d'Innovació Docent en Economia dels Impostos (GIDEI)

    2016-01-01

    Tema 7. Esquema de presentación del tema "Impuesto sobre la renta". Incorpora datos actuales, gráficos, cuadros y tablas. Esquema de presentació del tema "Impuesto sobre la renta". Incorpora dades actuals, gràfics, quadres i taules.

  6. Impuesto sobre sociedades

    OpenAIRE

    Universitat de Barcelona. Grup d'Innovació Docent en Economia dels Impostos

    2016-01-01

    Tema 8. Esquemas de la presentación del tema "Impuesto sobre sociedades". Incorpora datos actuales, gráficos, cuadros y tablas. Esquemes de la presentació del tema "Impuesto sobre sociedades". Incorpora dades actuals, gràfics, quadres i taules

  7. 3m Vacuum Ultraviolet Spectrometer with Optical Multichannel Detector; Espectrometro de ultravioleta de vacio de 3m provisto de sistema de deteccion optical multicanal

    Energy Technology Data Exchange (ETDEWEB)

    Martin, P.; Peraza, C.; Blanco, F.; Campos, J.

    1993-07-01

    This paper describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT. It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate / phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the array is digitized by a 12-bit analog to digital converter and stored in a computer, for its later analysis. The necessary software to store and display data has been developed. (Author) 18 refs.

  8. Efficient use of electric power in corporative 3M Mexico; Uso eficiente de la energia electrica en el corporativo 3M Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Perez, Alfredo; Quinones Bonilla, Antonio S. [3M Mexico, S.A. de C.V. (Mexico); Bustos Antunez, Jorge I.; Reyes Arce, Manuel [Hines Interests, S.A. de C.V. (Mexico)

    2003-07-01

    It is not enough to count on with the state of the art technology for the daily operation of a building, the challenge is to be able to make a clear analysis and with attainable goals for the optimization of rational use of the electrical energy in the operation of intelligent buildings without affecting the comfort and productivity for users as well as the functionality and profitability for the owner. This went our base to carry out control strategies that helped the efficient use of the electrical energy, obtaining important savings without neglecting the operative part, of services and human within the property. It is thus, that 3M Mexico wanting to reach these purposes, conducted actions to improve the efficiency of the equipment in the following items: electric network, general lighting, air conditioning system, ventilation and extraction, hydropneumatic system, and sumps operation. [Spanish] No basta contar con la tecnologia de punta para la operacion diaria de un edificio, el reto es ser capaces de realizar un analisis claro y con metas alcanzables para la optimizacion de uso racional de la energia electrica en las operaciones de edificios inteligentes sin afectar el confort y productividad para usuarios asi como la funcionalidad y rentabilidad para el propietario. Esta fue nuestra base para llevar a cabo estrategias de control que ayudaron al uso eficiente de la energia electrica, obteniendo ahorros importantes sin descuidar la parte operativa, de servicios y humana dentro de la propiedad. Es asi, que 3M Mexico queriendo alcanzar dichos propositos, realizo acciones para mejorar la eficiencia de los equipos en los siguientes rubros: red electrica, iluminacion general, sistema de aire acondicionado, ventilacion y extraccion, sistema hidroneumatico, y operacion de carcamos.

  9. Data of evolutionary structure change: 1AIJL-1DV3M [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1AIJL-1DV3M 1AIJ 1DV3 L M -----------------ALLSFERKYRVPGGTLV--GGN...> 0 1AIJ L 1AIJ...333125114440918 8.096282958984375 1 1AIJ L 1AIJL YGLGG...>ALA CA 332 GLU CA 290 ARG CA 277 1AIJ

  10. CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer.

    Directory of Open Access Journals (Sweden)

    Eira Valeria Barrón

    Full Text Available The cyclin-dependent kinase inhibitor 3 (CDKN3 gene, involved in mitosis, is upregulated in cervical cancer (CC. We investigated CDKN3 mRNA as a survival biomarker and potential therapeutic target for CC. CDKN3 mRNA was measured in 134 CC and 25 controls by quantitative PCR. A 5-year survival study was conducted in 121 of these CC patients. Furthermore, CDKN3-specific siRNAs were used to investigate whether CDKN3 is involved in proliferation, migration, and invasion in CC-derived cell lines (SiHa, CaSki, HeLa. CDKN3 mRNA was on average 6.4-fold higher in tumors than in controls (p = 8 x 10-6, Mann-Whitney. A total of 68.2% of CC patients over expressing CDKN3 gene (fold change ≥ 17 died within two years of diagnosis, independent of the clinical stage and HPV type (Hazard Ratio = 5.0, 95% CI: 2.5-10, p = 3.3 x 10-6, Cox proportional-hazards regression. In contrast, only 19.2% of the patients with lower CDKN3 expression died in the same period. In vitro inactivation of CDKN3 decreased cell proliferation on average 67%, although it had no effect on cell migration and invasion. CDKN3 mRNA may be a good survival biomarker and potential therapeutic target in CC.

  11. CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer.

    Science.gov (United States)

    Barrón, Eira Valeria; Roman-Bassaure, Edgar; Sánchez-Sandoval, Ana Laura; Espinosa, Ana María; Guardado-Estrada, Mariano; Medina, Ingrid; Juárez, Eligia; Alfaro, Ana; Bermúdez, Miriam; Zamora, Rubén; García-Ruiz, Carlos; Gomora, Juan Carlos; Kofman, Susana; Pérez-Armendariz, E Martha; Berumen, Jaime

    2015-01-01

    The cyclin-dependent kinase inhibitor 3 (CDKN3) gene, involved in mitosis, is upregulated in cervical cancer (CC). We investigated CDKN3 mRNA as a survival biomarker and potential therapeutic target for CC. CDKN3 mRNA was measured in 134 CC and 25 controls by quantitative PCR. A 5-year survival study was conducted in 121 of these CC patients. Furthermore, CDKN3-specific siRNAs were used to investigate whether CDKN3 is involved in proliferation, migration, and invasion in CC-derived cell lines (SiHa, CaSki, HeLa). CDKN3 mRNA was on average 6.4-fold higher in tumors than in controls (p = 8 x 10-6, Mann-Whitney). A total of 68.2% of CC patients over expressing CDKN3 gene (fold change ≥ 17) died within two years of diagnosis, independent of the clinical stage and HPV type (Hazard Ratio = 5.0, 95% CI: 2.5-10, p = 3.3 x 10-6, Cox proportional-hazards regression). In contrast, only 19.2% of the patients with lower CDKN3 expression died in the same period. In vitro inactivation of CDKN3 decreased cell proliferation on average 67%, although it had no effect on cell migration and invasion. CDKN3 mRNA may be a good survival biomarker and potential therapeutic target in CC.

  12. Coherently-combined two channel femtosecond fiber CPA system producing 3 mJ pulse energy.

    Science.gov (United States)

    Klenke, Arno; Seise, Enrico; Demmler, Stefan; Rothhardt, Jan; Breitkopf, Sven; Limpert, Jens; Tünnermann, Andreas

    2011-11-21

    We present a fiber CPA system consisting of two coherently combined fiber amplifiers, which have been arranged in an actively stabilized Mach-Zehnder interferometer. Pulse durations as short as 470 fs and pulse energies of 3 mJ, corresponding to 5.4 GW of peak power, have been achieved at an average power of 30 W.

  13. Intelligent Decision System Based on PA-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    A. Tejaswi,

    2010-03-01

    Full Text Available Due to the rapid advancement of electronic commerce and web technologies in recent years, the concepts and applications of decision support systems have been significantly extended. The demand placed on data that is loaded into the data warehouse and queried from the data warehouse has forced entrepreneurs and business users to manage the data. But the large commercial transactions have lots of useful knowledge for business decisions in the data warehouse. Through Intelligent Decisions, customers / entrepreneurs are able tomake effective decisions concerning the management and direction of their organization. This paper introduces business intelligent decisions that take place from the data-warehouse through the Actionable-Knowledge Discovery (AKD in Domain Driven Data Mining (D3M for short. The general architecture of D3M for enterprise decisions was proposed and the model storage was presented, and its characteristics would be analyzed. The deliverables of D3M were extracted from the result of data mining and knowledge base. Theenterprise decisions and reports could be analyzed through D3M deliverables.

  14. Syntheses, structures, optical properties, and electronic structures of KBaMSe{sub 3} (M = As, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Yin, Wenlong [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-306 Mianyang 621900 (China); Feng, Kai; Kang, Lei [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); University of the Chinese Academy of Sciences, Beijing 100049 (China); Kang, Bin; Deng, Jianguo [Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-306 Mianyang 621900 (China); Lin, Zheshuai [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Yao, Jiyong, E-mail: jyao@mail.ipc.ac.cn [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Wu, Yicheng [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-12-25

    Graphical abstract: KBaMSe{sub 3} (M = As, Sb) are isostructural and crystallize in the centrosymmetric monoclinic space group P2{sub 1}/c with zero-dimensional structures containing totally isolated MSe{sub 3} (M = As, Sb) pyramids with K{sup +} and Ba{sup 2+} cations lying between them. - Highlights: • Two new quaternary chalcogenides KBaMSe{sub 3} (M = As, Sb) were synthesized. • They are isostructural and crystallize in the centrosymmetric space group P2{sub 1}/c. • They adopt a zero-dimensional structure containing isolated MSe{sub 3} trigonal pyramids. • The optical band gaps are 2.26 (2) eV for KBaAsSe{sub 3} and 2.04 (2) eV for KBaSbSe{sub 3}. • KBaMSe{sub 3} (M = As, Sb) are indirect band gap semiconductors. - Abstract: The first two members in the quaternary A/A′/M/Q (A = alkali metal; A′ = alkaline-earth metal; M = As, Sb, Bi; Q = S, Se, Te) system, namely the KBaMSe{sub 3} (M = As, Sb) selenides, have been synthesized by solid state reactions. They are isostructural and crystallize in the centrosymmetric space group P2{sub 1}/c of the monoclinic system. In the structure, the trivalent M atom (M = As, Sb) is coordinated to three Se atoms forming a trigonal pyramid with the Se atoms serving as the triangle base, showing the stereochemical activity of the ns{sup 2} lone pair electron. The MSe{sub 3} (M = As, Sb) trigonal pyramids are totally isolated from each other with K{sup +} and Ba{sup 2+} cations located between them. The optical band gaps of 2.26 (2) eV for KBaAsSe{sub 3} and 2.04 (2) eV for KBaSbSe{sub 3}, were deduced from the diffuse reflectance spectra. The first principles calculations were performed to study the electronic structures of KBaMSe{sub 3} (M = As, Sb) compounds and the results indicated that these two compounds are indirect band gap semiconductors.

  15. Relevance of the ligand exchange rate and mechanism of fac-[(CO)3M(H2O)3]+ (M = Mn, Tc, Re) complexes for new radiopharmaceuticals.

    Science.gov (United States)

    Grundler, Pascal V; Helm, Lothar; Alberto, Roger; Merbach, André E

    2006-12-11

    The water exchange process on fac-[(CO)3Mn(H2O)3]+ and fac-[(CO)3Tc(H2O)3]+ was kinetically investigated by 17O NMR as a function of the acidity, temperature, and pressure. Up to pH 6.3 and 4.4, respectively, the exchange rate is not affected by the acidity, thus demonstrating that the contribution of the monohydroxo species fac-[(CO)3M(OH)(H2O)2] is not significant, which correlates well with a higher pKa for these complexes compared to the homologue fac-[(CO)3Re(H2O)3]+ complex. The water exchange rate K298ex/s(-1) (DeltaHex double dagger/kJ mol(-1); DeltaSex double dagger/J mol(-1) K(-1); DeltaV double dagger/cm3 mol-1) decreases down group 7 from Mn to Tc and Re: 23 (72.5; +24.4; +7.1) > 0.49 (78.3; +11.7; +3.8) > 5.4 x 10(-3) (90.3; +14.5; -). For the Mn complex only, an O exchange on the carbonyl ligand could be measured (K338co = 4.3 x 10(-6) s(-1)), which is several orders of magnitude slower than the water exchange. In the case of the Tc complex, the coupling between 17O (I = 5/2) and 99Tc (I = 9/2) nuclear spins has been observed (1J99Tc,17O = 80 +/- 5 Hz). The substitution of water in fac-[(CO)3M(H2O)3]+ by dimethyl sulfide (DMS) is slightly faster than that by CH3CN: 3 times faster for Mn, 1.5 times faster for Tc, and 1.2 times faster for Re. The pressure dependence behavior is different for Mn and Re. For Mn, the change in volume to reach the transition state is always clearly positive (water exchange, CH3CN, DMS), indicating an Id mechanism. In the case of Re, an Id/Ia changeover is assigned on the basis of reaction profiles with a strong volume maximum for pyrazine and a minimum for DMS as the entering ligand.

  16. Slow neutron beam control using multilayer supermirror and capillary guide at JRR-3M

    Energy Technology Data Exchange (ETDEWEB)

    Soyama, Kazuhiko [Center for Neutron Science, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan)

    1999-08-01

    Development of neutron optical devices at JRR-3M is reported. In order to reduce the interface roughness and enhance the reflectivity of supermirrors, ion polishing technique has been investigated for Ni/Ti multilayers. The optimum ion beam conditions of ion polishing time, ion energy and incident angle were determined, and the reflectivity of Ni/Ti has been successfully enhanced. For the application of supermirror, a natural nickel guide tube has been replaced with a supermirror guide tube at JRR-3M. It was evaluated using Monte-Carlo code that the total intensity at the end of a supermirror guide tube is 5.6 times that of the existing nickel guide tube. A silicate glass multi-capillary fiber fabricated and studied for the neutron transmission characteristics has been conducted. (author)

  17. Validation of the 3M molecular detection system for the detection of listeria in meat, seafood, dairy, and retail environments.

    Science.gov (United States)

    Fortes, Esther D; David, John; Koeritzer, Bob; Wiedmann, Martin

    2013-05-01

    There is a continued need to develop improved rapid methods for detection of foodborne pathogens. The aim of this project was to evaluate the 3M Molecular Detection System (3M MDS), which uses isothermal DNA amplification, and the 3M Molecular Detection Assay Listeria using environmental samples obtained from retail delicatessens and meat, seafood, and dairy processing plants. Environmental sponge samples were tested for Listeria with the 3M MDS after 22 and 48 h of enrichment in 3M Modified Listeria Recovery Broth (3M mLRB); enrichments were also used for cultural detection of Listeria spp. Among 391 samples tested for Listeria, 74 were positive by both the 3M MDS and the cultural method, 310 were negative by both methods, 2 were positive by the 3M MDS and negative by the cultural method, and one sample was negative by the 3M MDS and positive by the cultural method. Four samples were removed from the sample set, prior to statistical analyses, due to potential cross-contamination during testing. Listeria isolates from positive samples represented L. monocytogenes, L. innocua, L. welshimeri, and L. seeligeri. Overall, the 3M MDS and culture-based detection after enrichment in 3M mLRB did not differ significantly (P Bacteriological Analytical Manual method, further supporting that the 3M MDS performs equivalently to traditional methods when used with environmental sponge samples.

  18. Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

    Directory of Open Access Journals (Sweden)

    Omofoye Oluwaseun

    2008-05-01

    Full Text Available Abstract Background IGF binding protein-3 (IGFBP-3 regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of colorectal cancer (CRC, but the role of tissue IGFBP-3 is not well defined. We evaluated the association between tissue or plasma IGFBP-3 and risk of colorectal adenomas or low apoptosis. Methods Subjects were consenting patients who underwent a clinically indicated colonoscopy at UNC Hospitals and provided information on diet and lifestyle. IGFBP-3 mRNA in normal colon was assessed by real time RT-PCR. Plasma IGFBP-3 was measured by ELISA and apoptosis was determined by morphology on H & E slides. Logistic regression was used to compute odds ratio (OR and 95% confidence intervals. Results We observed a modest correlation between plasma IGFBP-3 and tissue IGFBP-3 expression (p = 0.007. There was no significant association between plasma IGFBP-3 and adenomas or apoptosis. Tissue IGFBP-3 mRNA expression was significantly lower in cases than controls. Subjects in the lowest three quartiles of tissue IGFBP-3 gene expression were more likely to have adenomas. Consistent with previous reports, low apoptosis was significantly associated with increased risk of adenomas (p = 0.003. Surprisingly, local IGFBP-3 mRNA expression was inversely associated with apoptosis. Conclusion Low expression of IGFBP-3 mRNA in normal colonic mucosa predicts increased risk of adenomas. Our findings suggest that local IGFBP-3 in the colon may directly increase adenoma risk but IGFBP-3 may act through a pathway other than apoptosis to influence adenoma risk.

  19. Ultra Barrier Topsheet Film for Flexible Photovoltaics with 3M Company

    Energy Technology Data Exchange (ETDEWEB)

    Funkenbusch, Arnold W. [3M Company, Saint Paul, MN (United States); Charles, Ruth P. [3M Company, Saint Paul, MN (United States)

    2014-12-30

    In this DOE sponsored program, 3M achieved the critical UBT features to enable durable flexible high efficiency modules to be produced by a range of customers who have now certified the 3M UBT and are actively developing said flexible modules. The specific objectives and accomplishments of the work under this program were; Scale-up the current Generation-1 UBT from 12” width, as made on 3M’s pilot line, to 1+meter width full-scale manufacturing, while maintaining baseline performance metrics (see table below); This objective was fully met; Validate service life of Generation-1 UBT for the 25+ year lifetime demanded by the photovoltaic market; Aggressive testing revealed potential failure modes in the Gen 1 UBT. Deficiencies were identified and corrective action taken in the Gen 2 UBT; Develop a Generation-2 UBT on the pilot line, targeting improved performance relative to baseline, including higher %T (percent transmission), lower water vapor transmission rate (WVTR) with targets based on what the technology needs for 25 year lifetime, proven lifetime of 25 years in solar module construction in the field, and lower cost; Testing of UBT Gen 2 under a wide range of conditions presented in this report failed to reveal any failure mode. Therefore UBT Gen 2 is known to be highly durable. 3M will continue to test towards statistically validating a 25 year lifetime under 3M funding; Transfer Generation-2 UBT from the pilot line to the full-scale manufacturing line within three years; and This objective was fully met.

  20. Florida hospital saves 5.3 M dollars by adopting principles of lean manufacturing.

    Science.gov (United States)

    2005-01-01

    Florida hospital saves 5.3M dollars by adopting principles of lean manufacturing. Surgery cancellations have been slashed from 13% of cases to less than 3%, while emergency department admissions have increased by 20%. Those are just two of the results of a quality improvement project at Lee Memorial Health System in Fort Myers, FL, that focused on using the principles of lean manufacturing to improve patient flow in the five-hospital system

  1. Peningkatan Aksesibilitas “3 M-Mobile Learning” sebagai Layanan Pendidikan

    Directory of Open Access Journals (Sweden)

    Deni Darmawan

    2014-06-01

    Full Text Available Pillars of education development in Indonesia as outlined in the National Education Strategic Plan is Pilar Access, Equity, Quality and Governance. This study tries to provide solutions pillar of success in schooling access learning services South West Java. Implementation of the research conducted in cooperation with Kemendikbud, Provincial Education Department, Office of education, UPTD, School, until teachers and students through the Department of Educational Technology faculty coordination. The purpose of this study are: ( 1 establish a system of mobile learning engine that can be used as an alternative to provide communications services distance learning schooling was in the southern region of West Java, (2 analyze the use of 3M - MLearning in increasing Accessibility teachers and students in learning in schooling algebra south. The method used is the Research and Development (R&D. The target of this study is 5 Banjar, Kudat District, Tasikmalaya, Pangandaran, Cianjur and Sukabumi. The results of this study, namely: ( 1 the product obtained mobile learning engine that supports learning communication services according to the needs of teachers and students in learning in schooling southern West Java, (2 There is a growing Accessibility 3M - MLearning online by teachers and students in supporting the learning of schooling algebra south. Renewable technology products of this research in the form of 3M MLearning website which can then be managed by the teacher, students through the ICT center in the region more broadly.

  2. Customer Relationship Management System with USCM-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    Ch. Raja Ramesh

    2010-09-01

    Full Text Available Customer Relationship Management (CRM for short System emerged in the last decade to reflect the central role of the customer for the strategic positioning of a company. One of the most significant changes in the practice of marketing during the last decade is the shift in emphasis from a transaction orientation customer to the CRM. Now a day’s it is an important edge but now a necessary tool for survival. CRM competence is very important source for enterprises to build and sustain competitive advantage. With the extensive applications in CRM enterprises have plenty of customer data. Main view of CRM is customer understanding, which is properly done will helps to understand customers and thus increases customer life time value. Effectively build CRM will maintain good relationships with customers. Companies have invested or are planning to invest huge amounts to implement CRM strategies, tools and infrastructures inorder to attract and retain profitable customers in today’s increasingly competitive markets. This paper introduces the architecture of RM based on Domain Driven Data Mining (D3M for short and with advanced technologies for knowing winning strategies. Italso discusses the important steps of designing the data warehouseand describes the meaning of D3M applied to the CRM and finally evolving of D3M to individual service are presented.

  3. Study of timing characteristics of a 3 m long plastic scintillator counter using waveform digitizers

    CERN Document Server

    Blondel, A.; Dubreuil, A.; Khotyantsev, A.; Korzenev, A.; Maalmi, J.; Mefodev, A.; Mermod, P.; Noah, E.

    2016-01-01

    A plastic scintillator bar with dimensions 3 m x 2.5 cm x 11 cm was exposed to a focused muon beam to study its light yield and timing characteristics as a function of position and angle of incidence. The scintillating light was read out at both ends by photomultiplier tubes whose pulse shapes were recorded by waveform digitizers. Results obtained with the WAVECATCHER and SAMPIC digitizers are analyzed and compared. A comprehensive discussion of the various factors affecting the timing resolution is presented. Prospects for applications of plastic scintillator technology in large-scale particle physics detectors with timing resolution around 100 ps are provided in light of the results.

  4. Theoretical study of 'Mixed' ligands superhalogens: Cl-M-NO3 (M = Li, Na, K)

    Science.gov (United States)

    Zhao, Xinghua; Liu, Weihui; Wang, Jiesheng; Li, Chun; Yuan, Guang

    2016-08-01

    MCl2-, M(NO3)2-, and (Cl-M-NO3)- (M = Li, Na, K) species are systematically investigated using the density functional theory. In all the cases studied, the vertical detachment energies (VDEs) exceed the electron affinity of chlorine atom, leading to the conclusion that MCl2-, M(NO3)2- and (Cl-M-NO3)- are superhalogens. The VDEs of (Cl-M-NO3)- are between that of MCl2- and M(NO3)2-, showing that replacing one ligand with a larger electronegative ligand leads to the higher VDE. Superhalogens with suitable VDEs can be built by using different ligands.

  5. Unique Roll-Off Roof for Housing 1.3 m Telescope at Devasthal, Nainital

    Science.gov (United States)

    Bangia, Tarun

    2017-06-01

    Aryabhatta Research Institute of Observational Sciences (ARIES) had set up a 1.3 m telescope at Devasthal, Nainital, India in the year 2010. Country's largest roll-off roof was indigenously designed, fabricated and installed on top of a building (17 × 8 m) for housing 1.3 m telescope. Telescope was supplied by M/s DFM Engineering Inc., USA to ARIES and was installed in the building with unique roll-off roof to protect it from external environment. Roll-off roof was designed and fabricated considering various parameters and available manpower and resources at ARIES. This paper presents mechanical development work, simple but distinct design approach and innovative selection of materials to economically manufacture roll-off roof of large size (8 × 8 × 4 m) at hilly remote site of Devasthal situated in Central Himalayan region. All operations in the roof viz. opening of shutters and rolling of roof were motorized to facilitate observers during night observations.

  6. Differential targeting of VDAC3 mRNA isoforms influences mitochondria morphology.

    Science.gov (United States)

    Michaud, Morgane; Ubrig, Elodie; Filleur, Sophie; Erhardt, Mathieu; Ephritikhine, Geneviève; Maréchal-Drouard, Laurence; Duchêne, Anne-Marie

    2014-06-17

    Intracellular targeting of mRNAs has recently emerged as a prevalent mechanism to control protein localization. For mitochondria, a cotranslational model of protein import is now proposed in parallel to the conventional posttranslational model, and mitochondrial targeting of mRNAs has been demonstrated in various organisms. Voltage-dependent anion channels (VDACs) are the most abundant proteins in the outer mitochondrial membrane and the major transport pathway for numerous metabolites. Four nucleus-encoded VDACs have been identified in Arabidopsis thaliana. Alternative cleavage and polyadenylation generate two VDAC3 mRNA isoforms differing by their 3' UTR. By using quantitative RT-PCR and in vivo mRNA visualization approaches, the two mRNA variants were shown differentially associated with mitochondria. The longest mRNA presents a 3' extension named alternative UTR (aUTR) that is necessary and sufficient to target VDAC3 mRNA to the mitochondrial surface. Moreover, aUTR is sufficient for the mitochondrial targeting of a reporter transcript, and can be used as a tool to target an unrelated mRNA to the mitochondrial surface. Finally, VDAC3-aUTR mRNA variant impacts mitochondria morphology and size, demonstrating the role of mRNA targeting in mitochondria biogenesis.

  7. Finishing of display glass for mobile electronics using 3M Trizact diamond tile abrasive pads

    Science.gov (United States)

    Zheng, Lianbin; Fletcher, Tim; Na, Tee Koon; Sventek, Bruce; Romero, Vince; Lugg, Paul S.; Kim, Don

    2010-10-01

    This paper will describe a new method being used during the finishing of glass displays for mobile electronics including mobile hand held devices and notebook computers. The new method consists of using 3M TrizactTM Diamond Tile Abrasive Pads. TrizactTM Diamond Tile is a structured fixed abrasive grinding technology developed by 3M Company. The TrizactTM Diamond Tile structured abrasive pad consists of an organic (polymeric binder) - inorganic (abrasive mineral, i.e., diamond) composite that is used with a water-based coolant. TrizactTM Diamond Tile technology can be applied in both double and single side grinding applications. A unique advantage of TrizactTM Diamond Tile technology is the combination of high stock removal and low sub-surface damage. Grinding results will be presented for both 9 micron and 20 micron grades of TrizactTM Diamond Tile abrasive pads used to finish several common display glasses including Corning GorillaTM glass and Soda Lime glass.

  8. Hubungan Sanitasi Lingkungan dan Tindakan 3M Plus Terhadap Kejadian DBD

    Directory of Open Access Journals (Sweden)

    rara marisdayana

    2016-02-01

    Full Text Available Sejak tahun 1968 sampai tahun 2012 World Health Organization (WHO mencatat negara Indonesia sebagai negara dengan kasus demam berdarah dengue yang tertinggi di Asia Tenggara. Pada tahun 2015 kasus DBD terus meningkat di Wilayah kerja puskesmas Kenali Besar, hal ini menyebabkan beberapa kelurahan yang berada di wilayah kerja puskesmas kenali besar termasuk daerah endemis DBD.Jenis Penelitian yaitu Penelitian kuantitatif dengan metode cross sectional. Sampel yang diambil dalam penelitian ini sesuai dengan kaedah proportional random sampling yaitu sebanyak 95 responden.Hasil analisis terdapat hubungan yang signifikan antara tempat penampungan air bersih dengan kejadian demam berdarah dengue diwilayah Kerja Puskesmas Kenali Besar (p value = 0,006 p≤ 0,05. terdapat hubungan yang signifikan antara Penyediaan tempat pembuangan sampah dengan kejadian demam berdarah dengue diwilayah Kerja Puskesmas Kenali Besar (p value = 0,002 p≤ 0,05. Terdapat hubungan yang signifikan antara tindakan 3M Plus dengan kejadian demam berdarah dengue diwilayah Kerja Puskesmas Kenali Besar (p value = 0,048 p≤ 0,05..           Ada hubungan antara sarana air bersih, penyediaan tempat sampah dan tindakan 3M Plus dengan kejadian DBD diwilayah Kerja Puskesmas Kenali Besar.

  9. Application of the S3M and Mcnpx Codes in Particle Detector Development

    Science.gov (United States)

    Pavlovič, Márius; Sedlačková, Katarína; Šagátová, Andrea; Strašík, Ivan

    2014-02-01

    Semiconductor detectors can be used to detect neutrons if they are covered by a conversion layer. Some neutrons transfer their kinetic energy to hydrogen via elastic nuclear scattering in the conversion layer, and protons are produced as recoils. These protons enter the sensitive volume of the detector and are detected. In the process of detector development, Monte Carlo computer codes are necessary to simulate the detection process. This paper presents the main features of the S3M code (SRIM Supporting Software Modules) and shows its application potential. Examples are given for the neutron detectors with a conversion layer and for CVD (Chemical Vapor Deposition) diamond detectors for beam-condition monitors at the LHC (Large Hadron Collider). Special attention is paid to the S3M statistical modules that can be of interest also for other application areas like beam transport, accelerators, ion therapy, etc. The results are generated by MCNPX (Monte Carlo N-Particle eXtended) simulations used to optimize the thickness of the HDPE (high density polyethylene) conversion layer.

  10. Assessment of irradiation effects on beryllium reflector and heavy water tank of JRR-3M

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, Yoji; Kakehuda, Kazuhiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-10-01

    The JRR-3M, a swimming pool type research reactor with beryllium and heavy water reflectors, has been operated since 1990. Since the beryllium reflectors are close to fuel and receive high fast neutron fluence in a relatively short time, they may be subject to change their dimensions by swelling due mostly to entrapped helium gaseous. This may bend the reflectors to the outside and narrow gaps between the reflectors and the fuel elements. The gaps have been measured with an ultrasonic thickness gage in an annual inspection. The results in 1996 show that the maximum of expansion in the diametral directions was 0.6 mm against 1.6 mm of a managed value for replacement of the reflector. A heavy water tank of the JRR-3M is made of aluminum alloy A5052. Surveillance tests of the alloy have been conducted to evaluate irradiation effects of the heavy water tank. Five sets of specimens of the alloy have been irradiated in the beryllium reflectors where fast neutron flux is higher than that in the heavy water tank. In 1994, one set of specimens had been unloaded and carried out the post-irradiation tests. The results show that the heavy water tank preserved satisfactory mechanical properties. (author)

  11. Mesa redonda sobre nuevos modelos organizativos en la gestión de proyectos digitales

    OpenAIRE

    Taladriz Mas, Margarita; Magriñá Contreras, Marta; Martín Marichal, Carmen; Cabo Rigol, Mercé; X Workshop Rebiun sobre proyectos digitales. Valencia, 7-8 Octubre de 2010

    2010-01-01

    Mesa redonda dentro del X Workshop Rebiun sobre proyectos digitales, celebrado en Valencia, 7-8 Ocubre de 2010, sobre: Nuevos modelos organizativos en la gestión de proyectos digitales. Moderador: José Manuel Barrueco (UV). Intervienen: Margarita Taladriz Mas(UC3M), Marta Magriñá Contreras (UNIRIOJA), Carmen Martín Marichal (ULPGC) y Mercé Cabo Rigol (UPF).

  12. Todo sobre el neobarroco

    Directory of Open Access Journals (Sweden)

    Arturo Carrera

    2007-07-01

    Full Text Available Lo que hemos escuchado y atendido hasta aquí, hoy, ayer, sobre todo en la propuesta poética esbozada por Sergio Raimondi en su ensayo sobre Aldo Oliva, demuestra que las singularidades, su pasión, anulan subrepticiamente las nominaciones.Anoche en la televisión una orquesta sinfónica y un coro numeroso. Súbitamente, me hubiera gustado ser uno de esos intérpretes solitarios para sí, a pesar de la armonía, anónimos, a pesar del brillo sonoro… un violín, un triángulo… apenas… tres grillos… como ...

  13. Resumen estudios sobre tabaquismo

    OpenAIRE

    Gónzalez, M.M. (M.)

    2009-01-01

    Este documento se realizó para publicar en la página Web de la Gerencia de Atención primaria del Área III. Este documento es una recopilación de estudios sobre tabaquismo. Gerencia de Atención Primaria Área III

  14. Multimedia sobre mantenimiento industrial

    National Research Council Canada - National Science Library

    2012-01-01

    ..., entre otras facilidades. Puntualizado, el mantenimiento industrial es una actividad que conserva la calidad del servicio que se presta, y sobre todo en la infraestructura existente en los centros de produccion con optimas condiciones de seguridad, eficiencia y economia. El mantenimiento es de gran importancia, pues sus objetivos son la base para un adecuado f...

  15. Ley sobre Realengos

    Directory of Open Access Journals (Sweden)

    Historia Social y de la Cultura Anuario Colombiano de

    1983-01-01

    Full Text Available Propuesta y Aprobada por el Senado y la Cámara de Antioquia en el año de 1.812 En nombre del Estado de Antioquia, el Senado y la Cámara de Representantes han decretado lo siguiente: Proyecto de Ley sobre Realengos: …

  16. GRACOS: Scalable and Load Balanced P3M Cosmological N-body Code

    CERN Document Server

    Shirokov, A; Shirokov, Alexander; Bertschinger, Edmund

    2005-01-01

    We present a parallel implementation of the particle-particle/particle-mesh (P3M) algorithm for distributed memory clusters. The GRACOS (GRAvitational COSmology) code uses a hybrid method for both computation and domain decomposition. Long-range forces are computed using a Fourier transform gravity solver on a regular mesh; the mesh is distributed across parallel processes using a static one-dimensional slab domain decomposition. Short-range forces are computed by direct summation of close pairs; particles are distributed using a dynamic domain decomposition based on a space-filling Hilbert curve. A nearly-optimal method was devised to dynamically repartition the particle distribution so as to maintain load balance even for extremely inhomogeneous mass distributions. Tests using $800^3$ simulations on a 40-processor beowulf cluster showed good load balance and scalability up to 80 processes. We discuss the limits on scalability imposed by communication and extreme clustering and suggest how they may be remove...

  17. Lattice relaxation and ferromagnetic character of (LaVO3)m/SrVO3superlattices

    Science.gov (United States)

    Schuster, Cosima; Lüders, Ulrike; Frésard, Raymond; Schwingenschlögl, Udo

    2013-08-01

    The experimental observation that vanadate superlattices (LaVO3)m/SrVO3 show ferromagnetism up to room temperature (Lüders U. et al., Phys. Rev. B, 80 (2009) 241102(R)) is investigated by means of density functional theory, and the band structure for m = 5 and 6 is calculated. A buckling of the interface VO2 layers is found in both cases, but subtle differences in bond length lead to very different properties for even and odd values of m: in the even case, the two interface VO2 layers effectively decouple from the adjacent LaO layers due to a strong bond length enhancement. This results into a local inversion of the orbital occupancy and to the confinement of the charge carriers. In the odd case, the amplitude of the bond length variation is smaller, so that the charge carriers spill into the deeper-lying VO2 layers, and spin-polarised interfaces are obtained.

  18. Characteristics of Transient Outward Potassium Channel Exposed to 3 mT Static Magnetic Field

    Institute of Scientific and Technical Information of China (English)

    LI Gang; CHENG Lijun; QIAO Xiaoyan; LIN Ling; ZHANG Lu; LI Yuanyuan

    2009-01-01

    Acutely isolated mouse hippocampai CA3 pyramidal neurons were exposed to 3 mT static magnetic field, and the characteristics of transient outward K+ channel were studied using the whole-cell patch-clamp tech-nique. The experiment revealed that the amplitude of transient outward potassium channel current was reduced. The maximum activated current densities of control group and exposure group were 163.62±20.68 pA/pF and 98.74±16.57 pA/pF(n=12, P0.05)and the slope factor of the inactivation curves from 8.69±0.80 mV to 10.87±1.02 mV(n=12, P<0.05). The results show that the static magnetic field can change the characteristics of transient outward K+ channel, and affect the physiological functions of neurons.

  19. 嵌入式工控机系统ARK-6310-3M04E

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    研华科技近期推出嵌入式工控机系统ARK-6310—3M04E,该产品配有Intel。ATOM处理器、Intel 945GSE芯片组和集成Mini—ITX母板,采用无风扇设计,可在恶劣环境中无噪声并可靠工作。该款紧凑、坚固型工业系统集成在一个多功能嵌入式机箱中,超紧凑的坚固构造,坚固的耳柄允许用户方便移动设备,扩展性能强,

  20. The refurbished 1.3-m Robotically Controlled Telescope at Kitt Peak

    Science.gov (United States)

    Gelderman, R.; Guinan, E.; Howell, S.; Mattox, J. R.; McGruder, C. H.; Walter, D. K.; Davis, D. R.; Everett, M.

    2003-05-01

    In 1999, the National Optical Astronomy Observatories (NOAO) announced the opportunity to "assume responsibility for operation of the Kitt Peak 1.3-m telescope." A group of astronomers/educators from institutions across the USA successfully proposed to refurbish and automate the observatory and operate it as the Robotically Controlled Telescope (RCT). The RCT Consortium has been established between Francis Marion University, the Planetary Science Institute, South Carolina State University, Villanova University, and Western Kentucky University to oversee the refurbishment and automation, and operate the telescope to successfully achieve its research and education goals. The RCT was commissioned in 1964 as the Remotely Controlled Telescope and utilized that epoch's computing and communication technology to provide unattended operation from NOAO headquarters in Tucson, about 90 km distant. The original incarnation of the RCT allowed astronomers to gain experience in the remote operation of observatories in order to both develop techniques for operating space-based telescopes and to increase the productivity of ground-based telescopes (Maran 1967 Science 158, 867). While these tests worked as well as could be expected given the technology of the time, the telescope and observatory were refitted in 1969 for classical, attended operations. The second life of the 1.3-m was as a heavily subscribed KPNO visitor facility, first with photoelectric photometers and later as an important testbed for the newest infrared instrumentation. In 1996 the telescope was removed from the list of available KPNO facilities and stood idle until the RCT Consortium hired EOS Technologies, Inc. to refurbish and automate the observatory. In winter 2003 most of the observatory systems have been refurbished and the commissioning has begun. Refurbishment of the RCT has been made possible by NASA grant NAG58762.

  1. Preparation of Solid Strong Acid Catalysts S2O2-8/ZrO2-Al2O3-M2O3(M=Cr,Ce,La)%固体强酸催化剂S2O2-8/ZrO2-Al2O3-M2O3(M=Cr,Ce,La)的制备

    Institute of Scientific and Technical Information of China (English)

    但悠梦

    2002-01-01

    @@ 固体强酸具有酸强度高,不腐蚀设备,不污染环境,与产物分离方便等特点,是一种对环境友好的催化剂. 业已发现固体强酸对许多重要的有机反应如烃类异构化、傅克酰基化、傅克烷基化、酯化、缩合、聚合、氧化等具有良好的催化活性,可替代传统的浓H2SO4及AlCl3、HF等高污染催化剂. 在前文[1]基础上,本文通过添加Cr2O3、Ce2O3和La2O3对催化剂S2O2-8/ZrO2-Al2O3改进后制备出S2O2-8/ZrO2-Al2O3-M2O3(M=Cr,Ce,La)系列固体强酸催化剂,用对乙酸和正丁醇的酯化转化率评价了催化活性,用XRD、BET、流动Hammett指示剂法和化学分析法分别表征了催化剂的晶型结构、比表面积、酸强度和硫含量,证实了催化剂对酯化反应具有良好的催化活性和重复使用性.

  2. Modeling the hydrothermal circulation and the hydrogen production at the Rainbow site with Cast3M

    Science.gov (United States)

    Perez, F.; Mügler, C.; Charlou, J.; Jean-baptiste, P.

    2012-12-01

    On the Mid-Atlantic Ridge, the Rainbow venting site is described as an ultramafic-hosted active hydrothermal site and releases high fluxes of methane and hydrogen [1, 2]. This behavior has first been interpreted as the result of serpentinization processes. But geochemical reactions involving olivine and plagioclase assemblages, and leading to chlorite, tremolite, talc and magnetite assemblages, could contribute to the observed characteristics of the exiting fluid [2]. The predominance of one of these geochemical reactions or their coexistence strongly depend on the hydrothermal fluid circulation. We developed and validated a 2D/3D numerical model using a Finite Volume method to simulate heat driven fluid flows in the framework of the Cast3M code [3, 4]. We also developed a numerical model for hydrogen production and transport that is based on experimental studies of the serpentinization processes [5-6]. This geochemical model takes into account the exothermic and water-consuming behavior of the serpentinization reaction and it can be coupled to our thermo-hydrogeological model. Our simulations provide temperatures, mass fluxes and venting surface areas very close to those estimated in-situ [7]. We showed that a single-path model [8] was necessary to simulate high values such as the in-situ measured temperatures and estimated water mass fluxes of the Rainbow site [7]. This single-path model will be used to model the production and transport of hydrogen at the Rainbow hydrothermal site. References [1]Charlou et al. (2010) AGU Monograph series. [2]Seyfried et al. (2011) Geochim. Cosmochim. Acta 75, 1574-1593. [3]http://www-cast3m.cea.fr. [4]Martin & Fyfe (1970) Chem. Geol. 6, 185-202. [5] Marcaillou et al. (2011) Earth and Planet. Sci. Lett. 303, 281-290. [6]Malvoisin et al. (2012) JGR, 117, B01104. [7]Perez et al. (2012) submited to Computational Geosciences. [8]Lowell & Germanovich (2004) AGU, Washington DC, USA.

  3. OBSL1 mutations in 3-M syndrome are associated with a modulation of IGFBP2 and IGFBP5 expression levels

    DEFF Research Database (Denmark)

    Huber, Celine; Fradin, Mélanie; Edouard, Thomas;

    2010-01-01

    3-M syndrome is an autosomal recessive disorder characterized by severe pre- and postnatal growth retardation and minor skeletal changes. We have previously identified CUL7 as a disease-causing gene but we have also provided evidence of genetic heterogeneity in the 3-M syndrome. By homozygosity m...

  4. 3M's Model Rewards and Recognition Program Engages Employees and Drives Energy Savings Efforts

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-06-11

    3M has implemented more than 1,900 employee-inspired projects that have realized a 22% improvement in energy efficiency and yielded $100 million in energy savings. This case study provides information about 3M's approach to energy efficiency.

  5. Comparative study of enamel adhesion between RelyX™ Unicem® (3M), a self-adhesive bonding agent, and the combination of MIP® (3M), a hydrophilic adhesive, and Transbond Supreme Low Viscosity® (3M), a traditional hydrophobic adhesive.

    Science.gov (United States)

    Dubernard, Charles; Raynal, Perrine; Tramini, Paul

    2013-09-01

    Although the bond strength of self-adhesive bonding agents is inferior to that of other families of adhesives, it is still adequate for orthodontic purposes provided prior enamel etching is performed. To determine the efficacy of RelyX™ Unicem(®) (3M) self-adhesive cement both in vitro and in vivo and to compare it with the combination of MIP(®) (3M), a moisture-insensitive primer, with a traditional hydrophobic adhesive, Transbond Supreme Low Viscosity(®) (3M). Comparison of bonding results on 23 trial dentures using RelyX™ Unicem(®) (3M) with bonding results on 29 trial dentures using a combination of MIP(®) and Transbond Supreme Low Viscosity(®) (3M), by means of a multipurpose Instron(®) 4444 testing machine. the breaking force of MIP(®)/Transbond Supreme Low Viscosity(®) (3M) (mean: 144±37.5 Newtons) was significantly higher than that of RelyX™ Unicem(®) (3M) (mean=110±26 Newtons) (P=0.001). A 12-month prospective, randomized, monocentric, single-blind clinical study in order to investigate the failure rate of orthodontic attachments according to the type of adhesive used, and the precise site of the debonding. Bracket bonding was performed on 16 patients with randomized allocation of the two adhesives to each of the semi-arches. The failure rates were: 15.3% for the MIP(®)/Transbond Supreme Low Viscosity(®) (3M) combination and 8.2% for the RelyX™ Unicem(®) (3M), with a significant difference (P=0.039). The more posterior the bonded teeth, the greater the superiority of RelyX™ Unicem(®) (3M). The in vivo results did not concord with those obtained in vitro. RelyX™ Unicem(®) (3M) exhibited lower adhesion values in vitro and yet it presented a debonding rate almost half that of the MIP(®)/Transbond Supreme Low Viscosity(®) (3M). The viscosity of RelyX™ Unicem(®) (3M) and its moisture tolerance would appear to account for these results. With prior etching, RelyX™ Unicem(®) (3M), a self-adhesive, self-etching bonding

  6. Inferencias sobre Grafos

    Directory of Open Access Journals (Sweden)

    Sira M. Allende

    2002-05-01

    Full Text Available El estudio de un juego puede ser modelado asumiendo que solo algunas partidas son observadas. Entonces el árbol del juego debe ser estimado utilizando información muestral. Similarmente ocurre al obtener información sobre el comportamiento de las decisiones tomadas por individuos muestreados sobre un árbol de decisión teórico. Al considerar una medida de probabilidad que caracterice el comportamiento de redes aleatorias se puede obtener un estimado del árbol asociado. Este problema es el analizado en este trabajo. Algunos resultados experimentales obtenidos usando Recocido Simulado ilustran el procedimiento. Su papel en el estudio de modelos económicos y de mercadeo es discutido.

  7. Tesis sobre municipalismo libertario

    OpenAIRE

    Bookchin, Murray

    2014-01-01

    Históricamente, la teoría y la práctica social radical se han centrado sobre dos campos de la actividad social humana: el lugar de trabajo y la comunidad. A partir de la creación del Estado-nación y de la Revolución Industrial, la economía ha ido adquiriendo una posición predominante sobre la comunidad; y no sólo en la ideología capitalista, sino también en los diferentes socialismos, libertarios y autoritarios, que han ido apareciendo en el último siglo. Este cambio de posición del socialism...

  8. Escrito sobre el cuerpo

    Directory of Open Access Journals (Sweden)

    Antonio Malalana Ureña

    2013-09-01

    Full Text Available El catálogo, en una edición bilingüe español-inglés, es una pequeña guía de la exposición Shirin Neshat. Escrito sobre el cuerpo, muestra que se integra dentro de los actos de PHOTOESPAÑA13, el festival internacional de fotografía y artes visuales. El esquema del libro es sencillo y los textos son extremadamente divulgativos. El primero de ellos, Escrito sobre el cuerpo (pp. 10-15, cuyo autor es Octavio Zaya, comisario de la exposición, resume la trayectoria de esta intelectual, que "interactúa" con la fotografía y los formatos audiovisuales, y nos presenta la argumentación narrativa de los documentos expuestos, contextualizando la obra recopilada.

  9. Theoretical studies of the paramagnetic perovskites MTaO{sub 3} (M = Ca, Sr and Ba)

    Energy Technology Data Exchange (ETDEWEB)

    Ali, Zahid, E-mail: zahidf82@gmail.com [Center for Computational Materials Science, University of Malakand, Chakdara, Dir (Lower) (Pakistan); Khan, Imad; Ahmad, Iftikhar; Khan, M. Salman [Center for Computational Materials Science, University of Malakand, Chakdara, Dir (Lower) (Pakistan); Asadabadi, S. Jalali [Department of Physics, Faculty of Science, University of Isfahan, Hezar Gerib Avenue, Isfahan, 81744 (Iran, Islamic Republic of)

    2015-07-15

    In the present density functional studies, structural, mechanical and magneto-electronic properties of CaTaO{sub 3,} SrTaO{sub 3} and BaTaO{sub 3} perovskites have been investigated. The calculated structural parameters by DFT and analytical methods are found consistent with the experiments. The analytically calculated tolerance factors of these compounds as well as their mechanical properties show that they are stable in the cubic phase. Furthermore elastic properties show that these materials are ductile in nature and confirm that BaTaO{sub 3} is harder than the rest compounds. The calculated spin dependent magneto-electronic properties reveal the paramagnetic metallic nature of these compounds. The electrical conductivity curve demonstrates significant conductivity above room temperature. On the basis of the presented properties it is expected that these compounds could be efficient electrode materials and need experimental investigations. - Highlights: • MTaO{sub 3} (M = Ca, Sr and Ba) perovskites are investigated theoretically in the frame work of density functional theory. • Mechanical properties explain the stability of these compounds and show that BaTaO{sub 3} is more ductile. • The magneto-electronic studies reveal the paramagnetic metallic nature of these compounds. • Significant electrical conductivity is observed above room temperature.

  10. GRACOS: Scalable and Load Balanced P3M Cosmological N-body Code

    Science.gov (United States)

    Shirokov, Alexander; Bertschinger, Edmund

    2010-10-01

    The GRACOS (GRAvitational COSmology) code, a parallel implementation of the particle-particle/particle-mesh (P3M) algorithm for distributed memory clusters, uses a hybrid method for both computation and domain decomposition. Long-range forces are computed using a Fourier transform gravity solver on a regular mesh; the mesh is distributed across parallel processes using a static one-dimensional slab domain decomposition. Short-range forces are computed by direct summation of close pairs; particles are distributed using a dynamic domain decomposition based on a space-filling Hilbert curve. A nearly-optimal method was devised to dynamically repartition the particle distribution so as to maintain load balance even for extremely inhomogeneous mass distributions. Tests using 800(3) simulations on a 40-processor beowulf cluster showed good load balance and scalability up to 80 processes. There are limits on scalability imposed by communication and extreme clustering which may be removed by extending the algorithm to include adaptive mesh refinement.

  11. Astrometric and Photometric Accuracy of the 1.3 m Robotically Controlled Telescope on Kitt Peak

    Science.gov (United States)

    McGruder, Charles H.; Carini, M. T.; Engle, S. G.; Gelderman, R.; Guinan, E. F.; Laney, D.; Strolger, L.; Treffers, R. R.; Walter, D. K.

    2014-01-01

    The 1.3 m (50 inch) telescope on Kitt Peak has been refurbished and provided with an autonomous scheduler. It is operated by The Robotically Controlled Telescope (RCT) consortium whose members are: South Carolina State, Villanova and Western Kentucky Universities. The facility possesses 5 board (UBVRI) and 11 narrow-band filters. Attached to the RCT camera is a 2048 x 2048 SITe SI-424A back-illuminated CCD with 24 micrometer pixels. We used over 7,000 star measurements from 37, 198s R-images to compute the astrometric and photometric accuracy. The difference of the J2000 coordinates computed from the RCT images and the J2000 Nomad catalog coordinate values in right ascension peaks at 0.058”, while the declination peaks at -0.125”. We obtained these astrometric results using the simplest assumptions: linear relationship between standard coordinates and measured coordinates, no color or magnitude dependency and no differential refraction (all images taken in the zenith). We express the photometric accuracy in the following manner: The Signal-to-Noise-Ratio as a function of apparent magnitude shows that the RCT is not noise dominated at m < 20 magnitude.

  12. 3M Petrifilm enterobacteriaceae count plate method for enumeration of enterobacteriaceae in selected foods: collaborative study.

    Science.gov (United States)

    Silbernagel, Karen M; Lindberg, Kathryn G

    2003-01-01

    The practice of detecting and enumerating all oxidase-negative, glucose-fermenting-Gram-negative rods (i.e., the family Enterobacteriaceae) is used to indicate unsanitary or inadequate food processing conditions. The objective of this interlaboratory collaborative study was to evaluate and compare the methods described in Standard Methods for the Examination of Dairy Products (SMEDP) and the Compendium of Methods for the Microbiological Examination of Foods (Compendium) with a commercial product, the 3M Petrifilm Enterobacteriaceae Count Plate, for the recovery of Enterobacteriaceae in foods. Six foods--cheddar cheese, milk, flour, frozen prepared meals, frozen broccoli, and nut pieces--were analyzed for Enterobacteriaceae by 12 collaborating laboratories. For each food tested, the collaborators received 8 blind test portions consisting of a control test portion and 3 levels of inoculated test portion, each in duplicate. Each test portion was tested by the Petrifilm Enterobacteriaceae Count Plate method as well as the SMEDP or Compendium methods. The precision estimates (repeatability or within-laboratory variation, and reproducibility or between-laboratory variation) were calculated with standard statistical techniques.

  13. Study of internal transport barriers in the initial phase of Ohmic discharges in TUMAN-3M

    Energy Technology Data Exchange (ETDEWEB)

    Askinazi, L G [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Bulanin, V V [St Petersburg State Polytechnical University, 195251 (Russian Federation); Vildjunas, M I [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Golant, V E [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Gorokhov, M V [St Petersburg State Polytechnical University, 195251 (Russian Federation); Kornev, V A [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Krikunov, S V [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Lebedev, S V [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Petrov, A V [St Petersburg State Polytechnical University, 195251 (Russian Federation); Rozhdestvensky, V V [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Tukachinsky, A S [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Zhubr, N A [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation)

    2004-05-01

    A regime with electron heat confinement improvement was recently found in the initial phase of discharges in the TUMAN-3M tokamak. An internal transport barrier (ITB) formation in this regime was confirmed by Thomson scattering measurements and by transport modelling. Two possible reasons for the ITB formation are discussed in the paper: by reduction of turbulent transport in the presence of low magnetic shear or by plasma sheared rotation. It is demonstrated that low magnetic shear formation is possible in the current ramp-up phase of the Ohmic discharge. The low magnetic shear does not seem to be the only reason for the transport reduction. Results of Doppler reflectometry measurements of poloidal rotation of density fluctuations are presented. It is found that core confinement improvement correlates with the appearance of sheared rotation of the density fluctuations and with a burst of the MHD activity. The ITB formation in the regime seems to be a result of a combined action of reduced magnetic shear and plasma sheared rotation.

  14. Oxidation, Reduction, and Condensation of Alcohols over (MO3)3 (M=Mo, W) Nanoclusters

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Zongtang; Li, Zhenjun; Kelley, Matthew S.; Kay, Bruce D.; Li, Shenggang; Hennigan, Jamie M.; Rousseau, Roger J.; Dohnalek, Zdenek; Dixon, David A.

    2014-10-02

    The reactions of deuterated methanol, ethanol, 1-propanol, 1-butanol, 2-propanol, 2-butanol and t-butanol over cyclic (MO3)3 (M = Mo, W) clusters were studied experimentally with temperature programmed desorption (TPD) and theoretically with coupled cluster CCSD(T) theory and density functional theory. The reactions of two alcohols per M3O9 cluster are required to provide agreement with experiment for D2O release, dehydrogenation and dehydration. The reaction begins with the elimination of water by proton transfers and forms an intermediate dialkoxy species which can undergo further reaction. Dehydration proceeds by a β hydrogen transfer to a terminal M=O. Dehydrogenation takes place via an α hydrogen transfer to an adjacent MoVI = O atom or a WVI metal center with redox involved for M = Mo and no redox for M = W. The two channels have comparable activation energies. H/D exchange to produce alcohols can take place after olefin is released or via the dialkoxy species depending on the alcohol and the cluster. The Lewis acidity of the metal center with WVI being larger than MoVI results in the increased reactivity of W3O9 over Mo3O9 for dehydrogenation and dehydration.

  15. CRM System Using UI-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    J.N.V.R.Swarup kumar,

    2010-03-01

    Full Text Available Customer Relationship Management has entered the mainstream. Despite the uncertainty of the economy, CRM is being thrust into corporate budgets and talked about as a critical initiative by numerous of companies. It has gone from being an important edge in the business world to a necessary tool for survival. Building an effective CRM system can get more effectively in acquiring new customers, increasing value of existing customers and retaining good customers. At the same time, the data of data warehouse will offer the best dataresource for the application of Domain Driven Data Mining (D3M for short on CRM. This paper introduces CRM and managing relationships with customers has become a critical organizational competency. Get winning strategies with the latent advanced technologies. Then ntroduces the architecture of CRM based on Domain Driven Data Mining, discusses the main steps of designing the Data warehouse and describes the meaning of Domain Driven Data Mining applied to CRM. Atlast, the promoting effects of Domain Driven Data Mining to individual service are presented .

  16. Visualization and measurement of pressurized multiphase flow using neutron radiography of JRR-3M system

    Energy Technology Data Exchange (ETDEWEB)

    Katoh, Yasuo [Yamaguchi Univ. (Japan); Matsubayasi, Masahito

    1998-01-01

    Concerning the transient phenomenon of solid-gas two-phase flow, an attempt was made to visualize and measure a flow phenomenon in which three-dimensional bubbles occurred, grew and collapsed in the vicinity of a gas injection nozzle while solid particles were circulating. Such a phenomenon could not or hardly be visualized and measured by conventional methods. Such two-phase flow was visualized using neutron radiography, its characteristics measured and the usefulness of the visualization by neutron radiography confirmed. For this purpose, three-dimensional fluidized bed vessels, rectangular or cylindrical-shaped, made of steel or aluminum sheet, were prepared. Polyethylene or glass beads were used as solid particles and activated carbon particles as the tracer. In the experiment, nitrogen gas was blown into the vessel from one nozzle and distributors provided at the bottom of the vessel and exhausted from the top via the exhaust valve, by which the pressure in the vessel was controlled. The imaging was done in the following way: A test chamber was provided beside the vessel to receive neutron beams from the JRR-3M system, the intensity of transmitted neutrons was converted to visible light by scintillator and the images were videotaped. The initial objectives of visualizing and measuring bubbles occurring, growing and collapsing and solid particles circulating in the solid-gas two-phase flow have been achieved by means of neutron radiography. (N.H.)

  17. Lattice relaxation and ferromagnetic character of (LaVO3)m/SrVO3 superlattices

    KAUST Repository

    Schuster, Cosima B.

    2013-08-01

    The experimental observation that vanadate superlattices (LaVO 3)m/SrVO3 show ferromagnetism up to room temperature (Lüders U. et al., Phys. Rev. B, 80 (2009) 241102(R)) is investigated by means of density functional theory, and the band structure for m = 5 and 6 is calculated. A buckling of the interface VO2 layers is found in both cases, but subtle differences in bond length lead to very different properties for even and odd values of m: in the even case, the two interface VO2 layers effectively decouple from the adjacent LaO layers due to a strong bond length enhancement. This results into a local inversion of the orbital occupancy and to the confinement of the charge carriers. In the odd case, the amplitude of the bond length variation is smaller, so that the charge carriers spill into the deeper-lying VO2 layers, and spin-polarised interfaces are obtained. © Copyright EPLA, 2013.

  18. KEPADATAN JENTIK Aedes aegypti SEBAGAI INDIKATOR KEBERHASILAN PEMBERANTASAN SARANG NYAMUK (3M PLUS: DI KELURAHAN SRONDOL WETAN, SEMARANG

    Directory of Open Access Journals (Sweden)

    Bhinuri

    2008-06-01

    Full Text Available Aedes aegypti larva density as an indicator of the success in mosquito breeding place irradication in East Srondol village, Semarang. Interventions have been done to reduce DHF incidence, such as fogging and suggestion to do 3 M plus, but ABJ (larva’s number of Semarang is still under the target. The best intervention is by doing 3M plus. The aims of this research are to know the relation between social characteristics, knowledge, and attitude with the habitual elimination 3 M Plus of mosquito sites, the relation between the habitual elimination 3 M Plus of mosquito sites with larva density, the larva density and also the prediction model of larva density from the habitual elimination 3 M Plus of mosquito sites. The research has been done at Kelurahan Srondol Wetan, with observational, quantitative, and explanatory research by using cross-sectional survey method. The population were the houses with the respondent-the person who did the habitual elimination 3 M Plus of mosquito sites. Sample number were 188 with stratified random sampling. The statistic test was the Kendalls Tau and multiple regresion. The result showed that there are relation between social characteristics such as education, family number, job, and salary, with the habitual elimination 3 M Plus of mosquito sites but there is no relation with age, knowledge and attitude. There are also relations between the habitual elimination 3 M Plus of mosquito sites at bath tub, water tub and also bucket with the larva density. Based on those results, Health Department of Semarang especially Community Health Center in Srondol Wetan expected to do health education about 3 M Plus at bath tub, bucket and water tub. Suggestion also addressed to the next researcher to use purposive sampling and water storage classification for the same research.

  19. The 1:3M geologic map of Mercury: progress and updates

    Science.gov (United States)

    Galluzzi, Valentina; Guzzetta, Laura; Mancinelli, Paolo; Giacomini, Lorenza; Malliband, Christopher C.; Mosca, Alessandro; Wright, Jack; Ferranti, Luigi; Massironi, Matteo; Pauselli, Cristina; Rothery, David A.; Palumbo, Pasquale

    2017-04-01

    After the end of Mariner 10 mission a 1:5M geologic map of seven of the fifteen quadrangles of Mercury [Spudis and Guest, 1988] was produced. The NASA MESSENGER mission filled the gap by imaging 100% of the planet with a global average resolution of 200 m/pixel and this led to the production of a global 1:15M geologic map of the planet [Prockter et al., 2016]. Despite the quality gap between Mariner 10 and MESSENGER images, no global geological mapping project with a scale larger than 1:5M has been proposed so far. Here we present the status of an ongoing project for the geologic mapping of Mercury at an average output scale of 1:3M based on the available MESSENGER data. This project will lead to a fuller grasp of the planet's stratigraphy and surface history. Completing such a product for Mercury is an important goal in preparation for the forthcoming ESA/JAXA BepiColombo mission to aid selection of scientific targets and to provide context for interpretation of new data. At the time of this writing, H02 Victoria [Galluzzi et al., 2016], H03 Shakespeare [Guzzetta et al., 2016] and H04 Raditladi [Mancinelli et al., 2016] have been completed and H05 Hokusai [Rothery et al., 2017], H06 Kuiper [Giacomini et al., 2017], H07 Beethoven and H10 Derain [Malliband et al., 2017] are being mapped. The produced geologic maps were merged using the ESRI ArcGIS software adjusting discontinuous contacts along the quadrangle boundaries. Contact discrepancies were reviewed and discussed among the mappers of adjoining quadrangles in order to match the geological interpretation and provide a unique consistent stratigraphy. At the current stage, more than 20% of Mercury has now a complete 1:3M map and more than 40% of the planet will be covered soon by the maps that are being prepared. This research was supported by the Italian Space Agency (ASI) within the SIMBIOSYS project (ASI-INAF agreement no. I/022/10/0). References Galluzzi V. et al. (2016). Geology of the Victoria Quadrangle (H

  20. Qualification Of Kapton Pretreatment Process Using 3M Scotch Weld 2216 For Solar Panel Application

    Science.gov (United States)

    Swamy, B. R.; Krishna, Priya G.; Venkatesh, K.; Nagendra, H. R.; Nanjundaswamy, T. S.

    2011-10-01

    Substrates for solar arrays intended to be used on satellite systems are generally made of aluminum honeycomb structure sandwiched with Carbon Fiber Reinforced Plastic (CFRP) face skin. Two mil thick KaptonTM sheets are co cured on one side of the aluminum /CFRP composite structure while realizing the substrate panels. This Kapton sheet would serve as an insulator over which solar cell blankets are bonded with suitable adhesive for the satellite solar panels. The satellite solar panels demands highest degree of quality and reliability and one of the prime factors in this regards is the bond strength of adhesive which is used to bond the solar cell blankets. Various methods of pretreatments of Kapton surface are in use for increasing the surface energy, which in turn results in improved bond strengths. These methods generally provide roughened surface of the Kapton which is achieved either by abrasive means like scrubbing the surface using fine silica chip, or plasma etching or alternatively by an additive process wherein suitable polyester, phenolic or other resins are coated on to the Kapton surface to achieve the desired results. For spacecraft solar panel applications at ISRO, polyester resin coating on to the Kapton surface was used as pretreatment prior to adhesive application. This process had provided adequate bond strengths between the solar cells and Kapton. Due to issues related to the supply of the polyester resin material from the vendor alternative methods of pretreatments were explored. In this paper, a novel process developed for Kapton pretreatment is described along with results of relevant qualifications for the satellite solar panel application. This newly developed pretreatment process for Kapton successfully adopts an epoxy based material 3M Scotch weld 2216 which is widely used in spacecraft electronic hardware.

  1. Clinical evaluation of the 3M Littmann Electronic Stethoscope Model 3200 in 150 cats.

    Science.gov (United States)

    Blass, Keith A; Schober, Karsten E; Bonagura, John D; Scansen, Brian A; Visser, Lance C; Lu, Jennifer; Smith, Danielle N; Ward, Jessica L

    2013-10-01

    Detection of murmurs and gallops may help to identify cats with heart disease. However, auscultatory findings may be subject to clinically relevant observer variation. The objective of this study was to evaluate an electronic stethoscope (ES) in cats. We hypothesized that the ES would perform at least as well as a conventional stethoscope (CS) in the detection of abnormal heart sounds. One hundred and fifty consecutive cats undergoing echocardiography were enrolled prospectively. Cats were ausculted with a CS (WA Tycos Harvey Elite) by two observers, and heart sounds were recorded digitally using an ES (3M Littmann Stethoscope Model 3200) for off-line analysis. Echocardiography was used as the clinical standard method for validation of auscultatory findings. Additionally, digital recordings (DRs) were assessed by eight independent observers with various levels of expertise, and compared using interclass correlation and Cohen's weighted kappa analyses. Using the CS, a heart murmur (n = 88 cats) or gallop sound (n = 17) was identified in 105 cats, whereas 45 cats lacked abnormal heart sounds. There was good total agreement (83-90%) between the two observers using the CS. In contrast, there was only moderate agreement (P <0.001) between results from the CS and the DRs for murmurs, and poor agreement for gallops. The CS was more sensitive compared with the DRs with regard to murmurs and gallops. Agreement among the eight observers was good-to-excellent for murmur detection (81%). In conclusion, DRs made with the ES are less sensitive but comparably specific to a CS at detecting abnormal heart sounds in cats.

  2. Analysis of current segmentation procedures within the 3M Industry and Transportation Department and recommendations for future segmentation approaches

    OpenAIRE

    Breitbach, Verena

    2012-01-01

    Abstract: The present Master thesis broaches the issue of market segmentation and its importance for the Industry and Transportation department of 3M Česko. Market segmentation has been recognized to be a very important tool for strategic marketing planning but currently, its implementation at 3M in the Czech Republic is in an early stage and therefore rather unorganized and not yet framed by precise guidelines. The hypothesis is that linking together need-based and descriptive customer behav...

  3. Tumor Necrosis Factor-related Apoptosis Ligand Induces Apoptosis in Prostate Cancer PC-3M Cell Line

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhohui; WANG Huafang; GU Longjie; YE Zhewei; XIAO Yajun

    2005-01-01

    To study the effect of tumor necrosis factor-related apoptosis inducing ligand (TRAIL)on PC-3M cell line, PC-3M cell line was incubated with gradient concentrations of TRAIL for 4-24h. Annixin-Ⅴ fluorescence staining and TUNEL method were employed to detect the apoptosis of PC-3M cells. The morphology of apoptotic PC-3M cells was observed by electron microscopy. The relationship between TRAIL concentrations and the percentage of apoptotic cells was evaluated by flow cytometry. The proliferation inhibitory ratio was calculated by using MTT colorimetry. Our results showed that apoptosis of PC-3M cells could be induced by treatment with TRAIL for at most 4 h. The results of flow cytometry and MTT colorimetry demonstrated a time- and concentration-dependent relationship between cell apoptosis rate and TRAIL concentration. It is concluded that apoptosis of PC-3M cells can be induced by TRAIL. Because of the selective killing effect of TRAIL on tumor ceils, it may become a potential alternative for the treatment of advanced prostate cancer.

  4. In vivo left ventricular assist induced coagulation derangements. Comparison of Sarns-3M and St. Jude Medical circuits.

    Science.gov (United States)

    Curtis, J J; Wagner-Mann, C C; Mann, F A; Demmy, T L; Walls, J T; Schmaltz, R A

    1997-01-01

    An in vitro comparison of centrifugal pumping systems manufactured by Sarns-3M and St. Jude Medical revealed a difference in blood cell derangement. The purpose of this study was to compare in vivo the effects of 96 hr of left ventricular assist (LVA) on indexes of coagulopathy, hemolysis, and complement activation. Two groups of calves (each: n = 5) were instrumented with identical left atrial to thoracic aorta centrifugal pumping circuits using either Sarns-3M or St. Jude centrifugal pumps. Laboratory evaluations were performed pre-assist and at 1, 4, 24, 48, 72, and 96 hr during LVA. Platelet counts dropped significantly by 24 hr (Sarns-3M: 28%; St. Jude: 30%); no significant change in function was noted. Activated clotting time increased slightly (p > 0.05). Prothrombin time increased at 4 and 24 hr of LVA, returning to baseline by 96 hr (p Sarns-3M device never reached significance. No significant changes in lactate dehydrogenase or plasma free hemoglobin were detected. Complement fraction C5a rose by 1 hr of LVA (p Sarns-3M and St. Jude LVA caused coagulation derangement in calves, 2) neither pump demonstrated an advantage regarding coagulation and complement parameters, 3) hemolysis observed with the Sarns-3M pump in vitro was not evidenced in vivo, and 4) in vitro evidenced centrifugal pump differences may not be realized in vivo.

  5. Puente sobre el Rin

    Directory of Open Access Journals (Sweden)

    Gortz, Wilhelm

    1961-12-01

    Full Text Available Del total de 35 proyectos presentados al concurso del puente para carretera sobre el Rin, entre Duisburg-Ruhrort y Homberg, sólo dos proposiciones de la Demag fueron consideradas: Una con tablero suspendido por vientos que parten de dos torres, y otra, con suspensión por cables flexibles que se apoyan en dos torres y anclaje en la misma estructura. Por razones netamente estéticas fue elegida la propuesta Demag de puente suspendido por cables, aunque la solución con vientos hubiera sido la más económica, teniendo en cuenta las condiciones existentes.

  6. Excertos sobre o sedentarismo

    OpenAIRE

    Alexandre Palma; Murilo Mariano Vilaça; Monique Ribeiro de Assis

    2014-01-01

    O sedentarismo tem sido tratado como algo perfeitamente determinável, objetivo e, portanto, que pode ser apreendido. Por outro lado, o conceito de sedentarismo ainda permanece questionável e, por conseguinte, os instrumentos mostram-se inconsistentes. Neste sentido, o objetivo do presente estudo foi mostrar que diferentes discursos de verdade vêm concorrendo por esse conceito, o que nos motiva a pensar qual é a verdade ou, até mesmo, se há alguma verdade sobre ele. Após apresentarmos diferent...

  7. Saber sobre la radio

    OpenAIRE

    Mata, María Cristina; Universidad Nacional de Córdoba. Argentina

    1998-01-01

    La autora propone en este artículo repensar los fundamentos sobre los cuales se estructuran las asignaturas y talleres de radio en las escuelas de Comunicación Social en Latinoamérica, con el proposito de romper la escisión  entre teoría/práctica y de no violentar su complejidad: en la radio, entendida como práctica comunicativa, se juega en primer lugar una "red de vinculaciones e intercambios" en condiciones privilegiadas para la dialoguicidad. En un segundo lugar, asociado al desarrollo de...

  8. Sobre historia mundial hoy

    Directory of Open Access Journals (Sweden)

    Vera Weiler

    2010-08-01

    Full Text Available Los procesos de globalización son una realidad; su enorme impacto sobre la vida humana los ha convertido en un tema recurrente sobre el que se escribe y se comenta a diario también en Colombia. Los libros que de ellos tratan, ante todo los que 10 hacen en tono crítico, baten records en la industria editorial en todo el mundo. Las expectativas que acerca del futuro abrigan cientos de millones de personas se relacionan con 10 que ellas esperan, para bien o para mal, de la globalización. Las posturas que los gobernantes ocupan al respecto en el mundo son, cuando menos de aceptación, generalmente de activa participación en pos de la globalización. Por un lado, crece la preocupación y se multiplican las protestas; por el otro, dominan los razonamientos de los especialistas en materia de maximización de los rendimientos de los capitales que presentan la globalización, al estilo que se viene imponiendo, como el camino ineludible del gobierno universal de la eficiencia. ¿Tienen que decir algo los historiadores frente a todo esto?.

  9. Sobre la tragedia griega

    Directory of Open Access Journals (Sweden)

    Mauricio Vélez Upegui

    2015-01-01

    Full Text Available Luego de caracterizar la tragedia griega clásica como expresión de un arte ciudadano que participa por igual de un carácter festivo, cierto régimen discursivo y una clara inscripción físico-espacial, el texto se demora en considerar tres aspectos fundamentales de esta forma dramática inventada por los griegos, a saber: una exposición sobre las fuentes orales míticas de las que los autores echan mano para componer la historia de cada una de las piezas que son llevadas a escena al amparo de un espíritu agonal; una explicación del funcionamiento formal de la tragedia, basado en la alternancia de partes cantadas (coro y partes recitadas (héroe; y, finalmente, una acotación sobre el sentido –interno y externo– que la acción dramática posee, en tanto elemento articulador de la trama.

  10. P3 mAb: An Immunogenic Anti-NeuGcGM3 Antibody with Unusual Immunoregulatory Properties.

    Science.gov (United States)

    Martínez, Darel; Rodríguez, Nely; Griñán, Tania; Rondón, Teresa; Vázquez, Ana María; Pérez, Rolando; Hernández, Ana María

    2012-01-01

    P3 is a murine IgM mAb that recognize N-glycosylated gangliosides, sulfatides, and antigens expressed in melanoma, breast, and lung human tumors. This antibody has the ability to trigger an IgG antibody response in the syngeneic BALB/c model, even when it is administered in the absence of adjuvant or carrier protein. The mechanism by which the P3 mAb, a self-immunoglobulin, induce this immune response in the absence of co-stimulatory or classical danger signals is still unknown. In the present paper we show that the high immunogenicity of P3 mAb depends not only on CD4 but also on CD8(+) T cells, since the depletion of CD8(+) or CD4(+) T cells led to the loss of P3 mAb immunogenicity in the syngeneic model. Furthermore, the immunization with P3 mAb enhanced the recovery of the CD8(+) T cell population in mice treated with an anti-CD8a antibody. Additionally, the immunization with P3 mAb restored the capacity of immunosuppressed mice to reject allogeneic tumors, a mechanism mediated by the action of CD8(+) T cells. Finally, in mice with cyclophosphamide induced lymphopenia, the administration of P3 mAb accelerated the recovery of both CD4(+) and CD8(+) T cells. These results show new possibilities for B and CD8(+) T cells interactions during the immune response elicited by a self-protein. Furthermore they point to P3 mAb as a potential interesting candidate for the treatment of immunosuppressed patients.

  11. P3 mAb: an immunogenic anti-NeuGcGM3 antibody with unusual immunoregulatory properties.

    Directory of Open Access Journals (Sweden)

    Darel eMartínez

    2012-04-01

    Full Text Available P3 is a murine IgM mAb that recognize N-glycolilated gangliosides, sulphatides and antigens expressed in melanoma, breast and lung human tumors. This antibody has the ability to trigger an IgG antibody response in the syngeneic BALB/c model, even when it is administered in the absence of adjuvant or carrier protein. The mechanism by which the P3 mAb, a self immunoglobuline, induce this immune response in the absence of co-stimulatory or classical danger signals is still unknown. In the present paper we show that the high immunogenicity of P3 mAb depends not only on CD4 but also on CD8+ T cells, since the depletion of CD8+ or CD4+ T cells led to the loss of P3 mAb immunogenicity in the syngeneic model. Furthermore, the immunization with P3 mAb enhanced the recovery of the CD8+ T cell population in mice treated with an anti-CD8a antibody. Additionally, the immunization with P3 mAb restored the capacity of immunosuppressed mice to reject allogeneic tumors, a mechanism mediated by the action of CD8+ T cells. Finally, in mice with cyclophosphamide induced lymphopenia, the administration of P3 mAb accelerated the recovery of both CD4+ and CD8+ T cells. These results show new possibilities for B and CD8+ T cells interactions during the immune response elicited by a self-protein. Furthermore they point to P3 mAb as a potential interesting candidate for the treatment of immunosuppressed patients.

  12. 2D and 3D Ultrasonographic Evaluation of Fetal Midface Hypoplasia in Two Cases with 3-M Syndrome.

    Science.gov (United States)

    Vimercati, A; Chincoli, A; de Gennaro, A C; DʼAddario, V; Cicinelli, E

    2016-07-01

    This paper highlights the utility of 2D and 3D ultrasonography in the prenatal diagnosis of facial dysmorphisms suggestive of very rare syndromes such as 3-M syndrome. Two pregnant women at risk for fetal skeletal dysplasias were referred to our clinic for 2D/3D ultrasound scan in the second trimester of pregnancy. Only one of the patients had a familial history of 3-M syndrome. Karyotyping and genetic testing of abortion material were performed in both cases. 2D ultrasonography revealed growth retardation of the long bones in both cases. In the case without a familial history of the syndrome, 2D and 3D ultrasonography showed an absence of nasal bones and a flat malar region suggestive of 3-M syndrome, although the difficult differential diagnosis included other dysmorphic growth disorders with prenatal onset. The karyotype was normal but the pregnancy was terminated in both cases. Postmortem examination confirmed 3-M syndrome as indicated by prenatal findings. In high-risk cases with a familial history of 3-M syndrome, prenatal diagnosis of 3-M syndrome is possible by analyzing fetal DNA. In the absence of risk, a definitive prenatal diagnosis is often not possible but may be suspected in the presence of shortened long bones, normal head size and typical flattened malar region (midface hypoplasia) shown on complementary 2D and 3D sonograms. 2D and 3D ultrasonography has been shown to offer reliable information for the prenatal study of skeletal and facial anomalies and can be useful if there is a suspicion of 3-M syndrome in a pregnancy not known to be at risk.

  13. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    Energy Technology Data Exchange (ETDEWEB)

    Cai, X.Z. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Huang, W.Y.; Qiao, Y.; Chen, Y.; Du, S.Y.; Chen, D.; Yu, S. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Liu, N. [Department of Nephrology, First Affiliated Hospital, China Medical University, Shenyang (China); Dou, L.Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Jiang, Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Department of Dermatology, First Affiliated Hospital, China Medical University, Shenyang (China)

    2014-10-17

    The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the expression of TIM-3 mRNA is associated with pathogenesis of SLE. Quantitative real-time reverse transcription-polymerase chain reaction analysis (qRT-PCR) was used to determine TIM-1, TIM-3, and TIM-4 mRNA expression in peripheral blood mononuclear cells (PBMCs) from 132 patients with SLE and 62 healthy controls. The PBMC surface protein expression of TIMs in PBMCs from 20 SLE patients and 15 healthy controls was assayed by flow cytometry. Only TIM-3 mRNA expression decreased significantly in SLE patients compared with healthy controls (P<0.001). No significant differences in TIM family protein expression were observed in leukocytes from SLE patients and healthy controls (P>0.05). SLE patients with lupus nephritis (LN) had a significantly lower expression of TIM-3 mRNA than those without LN (P=0.001). There was no significant difference in the expression of TIM-3 mRNA within different classes of LN (P>0.05). Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (r{sub s}=0.283, P=0.049) and serum albumin (r{sub s}=0.297, P=0.047). TIM-3 mRNA expression was weakly correlated with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; r{sub s}=-0.272, P=0.032). Our results suggest that below-normal expression of TIM-3 mRNA in PBMC may be involved in the pathogenesis of SLE.

  14. Anisotropic surface melting in lyotropic cubic crystals. Part 1: Pn3m/L1 interface, poor faceting.

    Science.gov (United States)

    Grenier, J; Plötzing, T; Rohe, D; Pieranski, P

    2006-02-01

    From experiments with ice or metal crystals, in the vicinity of their crystal/liquid/vapor triple points, it is known that melting of crystals starts on their surfaces and is anisotropic. It is shown here by direct observations under an optical microscope that this anisotropic surface melting phenomenon occurs also in lyotropic systems. In the case of C12EO2/water mixture, it takes place in the vicinity of the peritectic Pn3m/L3/L1 triple point. Above the peritectic triple point, where the Pn3m and L1 phases coexist in the bulk, the surface of a Pn3m-in-L1 crystal is composed of (111)-type facets surrounded by rough surfaces. The angular junction suggests that rough surfaces are wet by a L3-like layer while facets stay "dry". This is analogous to the pre-melting at rough surfaces in solid crystals. Upon cooling below the peritectic triple point, where L3 and L1 phases coexist in the bulk, a thick layer of the L3 phase grows from the pre-melted, rough Pn3m/L1 interface. Simultaneously, facets stay dry and their radius decreases. In this tri-phasic configuration, stable in a narrow temperature range, the L3/L1 and L3/Pn3m interfaces have shapes of constant mean curvature surfaces having common borders: edges of facets.

  15. Sobre multifunciones Fuzzy

    Directory of Open Access Journals (Sweden)

    Renato César Scarparo

    2002-01-01

    Full Text Available En este trabajo se presentan y demuestran algunos resultados de D.T. Luc y C, Vargas referentes a multifunciones con dominio y blanco en espacios vectoriales topológicos de Hausdorff sobre R, como así mismo se explícita el concepto de multifunción fuzzy de acuerdo a Papageogiou, y se demuestran dos teorema de S. S. Chag, con respecto a las multifunciones fuzzy, proposiciones todas estas, que integran una línea de resultados necesarios para la demostración de desigualdades variacionales para multifunciones fuzzy, a su vez necesarias, para la extensión fuzzy de conocido teorema de Walras.

  16. Sobre el Portugal ilustrado

    OpenAIRE

    Santolaya Heredero, Laura

    1992-01-01

    El mismo título invita a preguntarse, a modo de introducción, en qué consistió la Ilustración en Portugal. Me refiero a las prácticas, sin pretender entrar en un debate filosófico. Desde luego, las prácticas políticas y económicas de los Estados del XVIII poco tuvieron que ver con las ideas de los filósofos de la Ilustración. El fenómeno de la Ilustración se aprovechió de una propaganda anecdótica para hacer suponer a los lectores de libros sobre ella que en los diversos ...

  17. Excertos sobre o sedentarismo

    Directory of Open Access Journals (Sweden)

    Alexandre Palma

    2014-09-01

    Full Text Available O sedentarismo tem sido tratado como algo perfeitamente determinável, objetivo e, portanto, que pode ser apreendido. Por outro lado, o conceito de sedentarismo ainda permanece questionável e, por conseguinte, os instrumentos mostram-se inconsistentes. Neste sentido, o objetivo do presente estudo foi mostrar que diferentes discursos de verdade vêm concorrendo por esse conceito, o que nos motiva a pensar qual é a verdade ou, até mesmo, se há alguma verdade sobre ele. Após apresentarmos diferentes possibilidades de compreender o sedentarismo, através do uso de aforismos, entendemos que postular um discurso como verdade talvez apenas signifique que as pessoas nele creem e que há uma vontade de verdade como uma vontade voltada para o poder.

  18. Notas sobre o marcellismo

    Directory of Open Access Journals (Sweden)

    Jorge Sampaio

    2007-01-01

    Full Text Available Para el salazarismo, la estabilidad consistía en erradicar de la sociedad la elección de alternativas, esto es el conflicto. Ese orden comenzó a desmoronarse sobre todo desde los años 60, como consecuencia de los cambios socioeconómicos y culturales que acentuaban los factores de información y de concurrencia en la sociedad portuguesa. Ante este nuevo panorama, el éxito de Marcelo Caetano sólo era posible mediante un compromiso con los nuevos actores sociales y con las nuevas fuerzas políticas empeñadas en la instauración de la democracia. Sin embargo el Presidente del Consejo no quiso o no pudo asumir ese compromiso, viéndose obligado al cabo de un tiempo a volver sobre sus iniciales pasos aperturistas.The social and political stability under salazarism was contemplated as a result of alternatives choice and conflicts suppression. That order was mainly eroding along the decade of sixteenth as a consequence of social, economic and cultural changes that were accentuating information and concurrence factors in Portuguese society. Facing this new stage, the success of Marcelo Caetano’s reformism was depending on his capacity of commitment with the new social actors and the opposition political forces solidly engage in democratic goal. However, the President wasn’t capable —or wasn’t allowed— to assume this commitment, even reversing after the first hopeful times his initial reformist trends.

  19. CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes.

    Science.gov (United States)

    Wang, Miao-xing; Itoh, Masanori; Li, Shimo; Hida, Yoko; Ohta, Kazunori; Hayakawa, Miki; Nishida, Emika; Ueda, Masashi; Islam, Saiful; Tana; Nakagawa, Toshiyuki

    2016-01-29

    Cell death abnormal (ced)-3 and ced-4 genes regulate apoptosis to maintain tissue homeostasis in Caenorhabditis elegans. Apoptosome formation and CED-4 translocation drive CED-3 activation. However, the precise role of CED-4 translocation is not yet fully understood. In this study, using a combination of immunoprecipitation and reverse transcription-polymerase chain reaction methods in cells and a glutathione-S-transferase pull down assay in a cell-free system, we show that CED-4 binds ced-3 mRNA. In the presence of ced-3 mRNA, CED-4 protein is enriched in the microsomal fraction and interacts with ribosomal protein L10a in mammalian cells, increasing the levels of CED-3. These results suggest that CED-4 forms a complex with ced-3 mRNA and delivers it to ribosomes for translation.

  20. Sol-Gel Synthesis of LaMO3 (M = Cr, Mn, Fe, Co, Ni) Nanocrystalline Powders

    Institute of Scientific and Technical Information of China (English)

    Chen Zhanheng; Xing Xianran; Dai Jing; Huang Xiaowei; Li Hongwei

    2004-01-01

    Sol-gel synthesis of LaMO3 ( M = Cr, Mn, Fe, Co, Ni) nanocrystalline Powders was investigated. DSC measurement shows that precursors decomposed at about 403 K and 620 K to bum out of N, C, and H. The calcined samples at 1073 K were determined by XRD to be single phase. SEM observation shows that the prepared samples are nanocrystalline powders in broad sense. The average grain size of LaM'O3 (M'= Cr, Mn, Fe, Ni) is 150 ~700 nm,and the grain size of LaCoO3 is about 30 nm.

  1. UC3M team: estudiantes deportistas que alcanzan metas con esfuerzo, trabajo y pasión

    OpenAIRE

    García García , Juan; Martínez Bleda, Pablo; Moreno Sánchez, Rubén

    2015-01-01

    UC3M TEAM reúne a los mejores estudiantes deportistas que representan a la UC3M en los equipos de las distintas selecciones deportivas de la universidad. Contiene: entrevista con Juan García García, Entrenador del equipo femenino de voleibol (p. 10). -- Entrevista con Pablo Martínez Bleda, Capitán del Equipo de Rugby (p. 11). -- Entrevista con Rubén Moreno Sánchez, Medalla de bronce en el Campeonato Universitario de Taekwondo 2015 (p. 12)

  2. Fabrication of a silica aerogel and examination of its hydrophobic properties via contact angle and 3M water repellency tests

    Science.gov (United States)

    Mazrouei-Sebdani, Z.; Javazmi, L.; Khoddami, A.; Shams-Ghahfarokhi, F.; Low, T.

    2017-05-01

    Aerogels are dry gels with a very high specific pore volume. Aerogels with increased hydrophobicity have significant potential to expand their use as lightweight materials. Considering its special nanostructure and exceptional properties, this paper focuses on the synthesis and hydrophobic evaluation of a silica aerogel. The structural properties were investigated by measuring density, SEM micrographs, and BET analyses. Also, the hydrophobic evaluation was carried out by measuring 3M water repellency and water/alcohol contact angle. The BET analysis showed successful synthesis of the nanoporous silica aerogel with a pore size of 24 nm and porosity of 89%. The synthesized aerogel showed 3M water repellency of 3 and water contact angle of 129.6°. Also, it is worth-mentioning that as the alcohol content of the drops in 3M water repellency test is increased, the drop contact angle is decreased due to its lower surface tension. Thus, the contact angle reaches the zero at 3M water repellency test number of 4 (water/alcohol 60/40).

  3. Decrease of FOXP3 mRNA in CD4~+ T cells in latent autoimmune diabetes in adult

    Institute of Scientific and Technical Information of China (English)

    杨治芳

    2006-01-01

    Objective To study the percentage of peripheral blood CD4+ CD25+ T cells and the expression of F0XP3 mRNA in patients with latent autoimmune diabetes in adult (LADA). Methods Fresh peripheral blood samples were obtained from 60 patients with LADA,30 patients with type 2 diabetes and 30 age- and sex-matched

  4. A Study of confinement for $Q\\bar{Q}$ potentials on D3, M2 & M5 branes

    CERN Document Server

    Quijada, Edward

    2016-01-01

    We study analytically and numerically the interaction potentials between a pair of quark an anti-quark on D3, M2 and M5 branes. These potentials are obtained using Maldacena's method involving Wilson loops and present confining and non-confining behaviours in different situations that we explore in this work.

  5. Sobre la muerte voluntaria

    Directory of Open Access Journals (Sweden)

    Juan Álvarez-Cienfuegos Fidalgo

    2012-03-01

    Full Text Available El problema de cómo morir en nuestra sociedad se ha convertido en una inquietud para los ciudadanos y la reflexión moral. Especialmcnte por dos razones: por el desarrollo de la tecnología médica y por el hecho de que la mayor parte de los fallecimientos tienen lugar fuera del hogar, donde tradicionalmente ocurra el deceso. El presente artículo tiene como objetivo acercarse a esta cuestión. Para ello, se parte de la autonomía del ciudadano, con derecho a decidir sobre lo que considera cuál sea su manera de vivir y de morir. A tal fin, se hace una breve introducción sobre el dolor, el suicidio y la muerte, desde un punto de vista antropológico, pasando, después, a mostrar las cuestiones relacionadas con el problema de la eutanasia, donde la atención se dirigirá, ante todo, al enjuiciamiento crítico del tenso equilibrio en el que se mantienen dos principios fundamentales de la bioética: el de no maleficencia y el de autonomía del ciudadano.The problem of how to die in modern society has become a concern for both the citizen and moral reflection for two reasons in particular: due to developments in medical technology, and because most deaths occur outside the honre, where they traditionaÍlY took place. This paper addresses this issue, starting from citizen autonomy, the right to decide on what s/he considers to be his or her way of living and dying. To this end, a brief introduction considers pain, suicide and death from an anthropological viewpoint. Questions related to the problem of euthanasia are then exposed, with particular attention to, above all the critical judgement of the tense balance in which two fundamental principies of bioethics are held, the principle of non-maleficence and that of citizen autonomy.

  6. Debate sobre el parto (normal).

    OpenAIRE

    Vidal Puèrtolas, Adela

    2008-01-01

    El artículo pretende una reflexión sobre la asistencia al parto, desde el punto de vista de una comadrona. A raíz de la apuesta oficial sobre el cómo para humanizar la asistencia obstétrica hospitalaria, se plantea un análisis de las implicaciones profesionales y los matices culturales que influyen sobre la vivencia de la experiencia del parto. La importancia de la psico-profilaxis en la preparación al parto como vehículo terapéutico de acercamiento a la realidad y de ...

  7. Evaluation of 3M Molecular Detection System and ANSR Pathogen Detection System for rapid detection of Salmonella from egg products.

    Science.gov (United States)

    Hu, L; Ma, L M; Zheng, S; He, X; Wang, H; Brown, E W; Hammack, T S; Zhang, G

    2017-05-01

    Isothermal amplification assay is a novel simple detection technology that amplifies DNA with high speed, efficiency, and specificity under isothermal conditions. The objective of this study was to evaluate the effectiveness of the 3M Molecular Detection System (MDS) and ANSR Pathogen Detection System (PDS) for the detection of Salmonella in egg products as compared to the Food and Drug Administration's Bacteriological Analytical Manual (BAM) culture method and a modified culture method (3M MDS and ANSR PDS preferred method). Two Salmonella ser. Enteritidis (18579, PT4; CDC_2010K_1441, PT8), one Salmonella ser. Heidelberg (607310-1), and one Salmonella ser. Typhimurium (0723) isolates were used in this study. Seven wet egg products and 13 dry egg products were inoculated with these strains individually at 1 to 5 CFU/25 g. One set of test portions was prepared following FDA BAM procedures [with lactose broth (LB) as pre-enrichment broth]. Another set of test portions was prepared using buffered peptone water (BPW) as pre-enrichment broth, as instructed by the 2 detection systems. Results from 3M MDS and ANSR PDS were 100% in agreement with their BPW-based culture method results. When LB was used as pre-enrichment broth, the number of Salmonella positive test portions (80 tested), identified with the BAM, 3M MDS, and ANSR PDS, were 63, 61, and 60, respectively. In conclusion, both 3M MDS and ANSR PDS Salmonella assays were as effective as their BPW based culture methods and were equivalent to the BAM culture method for the detection of Salmonella in egg products. These sensitive isothermal assays can be used as rapid detection tools for Salmonella in egg products provided that BPW is used as pre-enrichment broth. Published by Oxford University Press on behalf of Poultry Science Association 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  8. Puente sobre el Maracaibo

    Directory of Open Access Journals (Sweden)

    Equipo Editorial

    2017-05-01

    Full Text Available Para salvar el lago de Maracaibo (Venezuela, el conocido ingeniero italiano Riccaido Morandi ha presentado un proyecto de puente para ferrocarril y carretera, de hormigón pretensado, de tramos independientes, constituyendo un sistema Gerber, que tiene una longitud total de 8.720 m y un vano central de 400 m de luz. Este último tramo, en unión de los dos adyacentes al mismo, constituirán, una vez terminada la obra, un conjunto continuo. El tablero del puente se halla a una altura de 45 m sobre el nivel del agua en la zona del canal, con objeto de permitir la navegación. El tablero, de 20,90 m de anchura total, se ha subdividido en tres partes, dos simétricas respecto al eje, laterales, de 7,20 m de anchura, para la circulación en sentidos opuestos por carretera, una plataforma central, de 5 m de ancho, para el ferrocarril y dos andenes para el paso de peatones y servicios.

  9. Debate internacional sobre pobreza

    Directory of Open Access Journals (Sweden)

    Neritza Alvarado Chacín

    2016-01-01

    Full Text Available El objetivo del artículo es organizar la proliferación de ideas en torno de la pobreza, a menudo dispersas, difusas y confusas en la literatura, bosquejando sistematizadamente un marco teórico referencial útil al abordaje científico de este fenómeno, en investigaciones teóricas y aplicadas, así como en la enseñanza y discusión de tales temas en el ámbito universitario. Para ello, se compendian, organizan y clasifican diversos enfoques sobre la pobreza, según los criterios presentes en los planteamientos de autores e instituciones relevantes que han contribuido a la reflexión desde distintas lecturas, teniendo en cuenta que no existe consenso en torno a una definición. La investigación es exploratoria-documental. Se aplican las técnicas del arqueo electrónico y físico de la información, el fichaje computarizado y la reducción de la misma en tablas de contenido. Se precisa el alcance de las mismas en el tiempo, según la evolución conceptual que han experimentado en el debate internacional. Se señalan algunas ventajas y desventajas de los principales enfoques, que han sido reconocidas en el mismo debate.

  10. Sobre el nombre "Quechua"

    Directory of Open Access Journals (Sweden)

    Rodolfo Cerrón-Palomino

    1985-06-01

    Full Text Available Uno de los primeros problemas con el que a menudo tropiezael estudioso de los idiomas ágrafos, como es el caso de las lenguasaborígenes de América, es el de su denominación (glotónimo.En la medida ,en que, por razones históricas, las noticias sobretales lenguas, y por consiguiente los primeros estudios sobre lasmismas, surgen a partir del contacto con los miembros de la civilización occidental, los nombres de los distintos idiomas, así comode los grupos étnicos que los manejan, son el resultado casi siempre arbitrario cie designaciones fortuitas hechas por viajeros, misiioneros y exploradores, quienes por lo general se basan, para ello, bien en descripciones físicas de los grupo étnicos, en ciertos indios geográficos que constituyen el habitat de los mismos, e incluso en prejuicios que se nutren de un marcado europocentrismo.

  11. Sobre invenciones y truculencias

    Directory of Open Access Journals (Sweden)

    Rafael Mendez

    2016-01-01

    Full Text Available Es muy probable que, antes que la experiencia misma de la vida, lo que nos constituye y nos otorga sentido, sea la versión que podamos construir a partir de esa experiencia. Su memoria. Pero esa construcción no se da, bajo ninguna circunstancia, de manera natural o desinteresada. Todo lo contrario, el territorio que ocupa es básicamente conflictivo, hecho de pura tensión, de forcejeos sin tregua al final de los cuales se resuelve una imposición: alguien, algunos, consiguen obligar a los demás a reconocer su versión, como la versión de todos, lo que implica, en definitiva, olvidar su artificialidad básica, pasar por alto su naturaleza arbitraria y por lo tanto, perfeccionar, de manera casi siempre tácita y silenciosa, su naturalización. Así las cosas, y en consecuencia de tamaña truculencia, los hechos y las experiencias que constituyen nuestro día a día, se nos dan de una manera que podríamos calificar de incontestable. Están ahí: ocupan su momento y su lugar, despliegan sus circunstancias. Su contundencia es tal, que el armazón entero de eso que llamamos realidad, construye sobre el poder de esa evidencia el conjunto pleno de sus estrategias y complejidades. Confianza descomunal, pues esa realidad, tan airosa y, en tantas oportunidades, tan arrogante, termina constituyéndose en mundo. En nuestro mundo. El único que, aparentemente, nos corresponde y que se nos impone en la “verdad” de la experiencia y de la memoria.

  12. Algunos apuntes sobre comunidad

    Directory of Open Access Journals (Sweden)

    Clara Pérez Cárdenas

    2000-08-01

    Full Text Available Comunidad es, entre los temas de estudio del curriculum de los residentes en Medicina General Integral, uno de aquellos en las que mayores dificultades encontramos para poderlo impartir, pues la bibliografía sobre el tema está un tanto dispersa. Es un aspecto que los propios residentes no evalúan con justeza; sin embargo es de sumo interés que como profesionales de la salud no obviemos que nuestro trabajo de promoción, prevención y tratamiento, debe darse a nivel de individuo, pero también en las familias y en la comunidad como un todo, y por lo tanto debamos incorporar, al menos, nociones de lo que es una comunidad y qué es participación comunitaria para tener idea de cómo fomentarla, única vía para que nuestras acciones de salud sean más efectivasCommunity is one of the most difficult subjects to be taught among those included in the curriculum of General Comprehensive Medicine residents, since bibliography on this topic is a bit dispersed. This aspect, which is not properly evaluated by residents, is very important for health professionals to do our work of promotion, prevention and treatment not only at the level of the individual, but also at the level of the family and of the community as a whole. Therefore, we need to have some notions about community and community participation to be able to promote them, as the only way to make our health actions more effective

  13. N- and O-linked glycosylation site profiling of the human basic salivary proline-rich protein 3M.

    Science.gov (United States)

    Manconi, Barbara; Cabras, Tiziana; Sanna, Monica; Piras, Valentina; Liori, Barbara; Pisano, Elisabetta; Iavarone, Federica; Vincenzoni, Federica; Cordaro, Massimo; Faa, Gavino; Castagnola, Massimo; Messana, Irene

    2016-05-01

    In the present study, we show that the heterogeneous mixture of glycoforms of the basic salivary proline-rich protein 3M, encoded by PRB3-M locus, is a major component of the acidic soluble fraction of human whole saliva in the first years of life. Reversed-phase high-performance liquid chromatography with high-resolution electrospray ionization mass spectrometry analysis of the intact proteoforms before and after N-deglycosylation with Peptide-N-Glycosidase F and tandem mass spectrometry sequencing of peptides obtained after Endoproteinase GluC digestion allowed the structural characterization of the peptide backbone and identification of N- and O-glycosylation sites. The heterogeneous mixture of the proteoforms derives from the combination of 8 different neutral and sialylated glycans O-linked to Threonine 50, and 33 different glycans N-linked to Asparagine residues at positions 66, 87, 108, 129, 150, 171, 192, and 213.

  14. PMO[KIT-5]-n: synthesis of highly ordered three-dimensional periodic mesoporous organosilicas with Fm3m symmetry.

    Science.gov (United States)

    Liang, Yucang; Hanzlik, Marianne; Anwander, Reiner

    2005-01-28

    Divalent surfactant [CH3(CH2)15N(CH3)2(CH2)3N(CH3)3]2+ - 2Br- (C16-3-1) was used as a structure directing agent (SDA) for the synthesis of highly ordered periodic mesoporous organosilicas (PMOs) with cubic Fm3m symmetry from 1,2-bis(triethoxylsilyl)ethane (BTEE) under basic conditions.

  15. Heat flux measurements of Tb3M series (M=Co, Rh and Ru): Specific heat and magnetocaloric properties

    Science.gov (United States)

    Monteiro, J. C. B.; Lombardi, G. A.; dos Reis, R. D.; Freitas, H. E.; Cardoso, L. P.; Mansanares, A. M.; Gandra, F. G.

    2016-12-01

    We report on the magnetic properties and magnetocaloric effect (MCE) for the Tb3M series, with M=Co, Rh and Ru, obtained using a heat flux technique. The specific heat of Tb3Co and Tb3Rh are very similar, with a first order type transition occurring around 6 K below the magnetic ordering temperature without any corresponding feature on the magnetization. The slightly enhanced electronic specific heat, the Debye temperature around 150 K and the presence of the magnetic specific heat well above the ordering temperature are also characteristic of many other compounds of the R3M family (R=Rare Earth). The specific heat for Tb3Ru, however, presents two peaks at 37 K and 74 K. The magnetization shows that below the first peak the system presents an antiferromagnetic behavior and is paramagnetic above 74 K. We obtained a magnetocaloric effect for M=Co and Rh, -∆S=12 J/kg K, but for Tb3Ru it is less than 3 J/kg K (μ0∆H=5 T). We believe that the experimental results show that the MCE is directly related with the process of hybridization of the (R)5d-(M)d electrons that occurs in the R3M materials.

  16. Deposition of LaMO3 (M=Ni,Co,Cr,Al)-Oriented Films by Spray Combustion Flame Technique

    Science.gov (United States)

    Ichinose, Hiromichi; Shiwa, Yuzo; Nagano, Masamitsu

    1994-10-01

    LaMO3 (M=Ni,Co,Cr,Al) films were prepared on sintered alumina, sapphire (001) and MgO(100) at 500 900°C by spraying ultrasonically atomized aqueous solutions of nitrates into a combustion flame (spray combustion flame technique). LaNiO3 and LaCoO3 on MgO(100) crystallized in high-temperature phases (cubic) while LaCrO3 and LaAlO3 crystallized in room-temperature phases. LaMO3 (M=Ni,Co,Cr,Al) films on MgO(100) were highly oriented to (100), (100), (001) and (100), respectively, while the films on sintered alumina and sapphire were not. The electric resistivities of the dense LaMO3 (M=Ni,Co,Cr) films were as low as those of bulk ceramics. LaNiO3 film deposited on MgO above 700°C showed the lowest resistivity of about 6×10-6 Ω m. It was suggested that the reactivities of the constituent metal atoms with OH in the flame are associated with the preferred phase and the morphology of the films.

  17. Design of multichord Hα detector arrays for the U-3M torsatron and identification of rotating plasma perturbations

    Science.gov (United States)

    Dreval, M. B.; Shapoval, A. M.; Ozherelyev, F. I.; Makhov, M. M.

    2016-07-01

    An Hα camera has been designed and installed in the U-3M torsatron for spatially and temporally resolved measurements. This device provides fast measurements of the emission brightness profile in the noisy environment of the radio frequency (RF) heated plasma. Unusual topology of diagnostics and the data acquisition system are applied. All the system components, including digitizers, are assembled in a single unit. It allows the suppression of a low-frequency electromagnetic interference by eliminating the ground loops. And the suppression of RF noises is achieved by eliminating the signal interface cables and digital interface cables in the design. The Wi-Fi interface is used to prevent a ground loop in the data transfer stage. The achieved sensitivity of our diagnostics is high enough for measuring the Hα emission from the low-density (ne ≈ (1-2)ṡ1010 cm-3) plasma with a temporal resolution of about 20 μs in the noisy environment. Different types of Hα emission fluctuations within the frequency range of 1-5 kHz and poloidal mode numbers m = 0 and m = 5 have been observed in U-3M. A simple technique of the line-of-sight data analysis, based on the U-3M magnetic surface asymmetry, is proposed and used for the spatial localization of the rotating mode and for the determination of mode numbers and its poloidal rotation direction using a single Hα array.

  18. Hydrothermal synthesis and luminescent properties of CaWO4: 3 + M3 + Eu , ( M = Tb, Sm, Bi, Dy)%CaWO4:Eu3+,M3+(M=Tb,Sm,Bi,Dy)的水热合成及发光性能研究

    Institute of Scientific and Technical Information of China (English)

    张丽霞; 梁利芳; 唐上惠; 易敏; 庞起

    2011-01-01

    利用水热合成法制备CaWO4∶Eu3+以及CaWO4∶Eu3+,M3+(M=Tb,Sm,Bi,Dy)系列钨酸盐基荧光粉,利用XRD表征产物CaWO4∶Eu3+(5%)的晶体结构,结果表明其结构和CaWO4的标准物相结构相似,为四方晶系结构;研究了CaWO4∶Eu3+的发光性能以及第二掺杂离子M3+(M=Tb,Sm,Bi,Dy)对荧光粉发光性能的影响,结果表明,在273 nm紫外光激发下,掺入Tb3+和Sm3+离子对CaWO4基质发光强度没有明显影响,但能增强荧光粉中Eu3+离子617 nm处的红光发射强度;掺入Bi3+和Dy3+离子能明显降低CaWO4基质的发光强度,同时能增强荧光粉中Eu3+离子617 nm处的红光发射强度.%Tungstate-based phosphors CaWO4: Eu3 + and CaWO4: Eu3 + , M3 + ( M = Tb, Sm, Bi,Dy) were prepared successfully by hydrothermal synthesis method. The crystal structure of CaWO4:Eu3+ (5%) characterized by XRD was tetragonal system, which was in accordance with CawO4 ( JCPDS file 85 - 0443 ). The luminescent properties of CaWO4: Eu3 + and the effect of M3 + ( M = Tb,Sm, Bi, Dy) on the luminescent properties of the fluorescent powder were investigated. Under the excitation of 273 nm, either Tb3 + or Sm3 + had no obvious effect on the emission intensity of CaWO4,but can enhance the intensity of 617 nm emission of Eu3+ ion. On the other hand, either Bi3 + or Dy3+ ion can reduce the emission intensity of CaWO4 and enchance the intensity of 617 nm emission of Eu3 + ion.

  19. Evaluation of 3M molecular detection assay (MDA) Salmonella for the detection of Salmonella in selected foods: collaborative study.

    Science.gov (United States)

    Bird, Patrick; Fisher, Kiel; Boyle, Megan; Huffman, Travis; Benzinger, M Joseph; Bedinghaus, Paige; Flannery, Jonathan; Crowley, Erin; Agin, James; Goins, David; Benesh, DeAnn; David, John

    2013-01-01

    The 3M Molecular Detection Assay (MDA) Salmonella is used with the 3M Molecular Detection System for the detection of Salmonella spp. in food, food-related, and environmental samples after enrichment. The assay utilizes loop-mediated isothermal amplification to rapidly amplify Salmonella target DNA with high specificity and sensitivity, combined with bioluminescence to detect the amplification. The 3M MDA Salmonella method was compared using an unpaired study design in a multilaboratory collaborative study to the U.S. Department of Agriculture/Food Safety and Inspection Service-Microbiology Laboratory Guidebook (USDA/FSIS-MLG 4.05), Isolation and Identification of Salmonella from Meat, Poultry, Pasteurized Egg and Catfish Products for raw ground beef and the U.S. Food and Drug Administration/Bacteriological Analytical Manual (FDA/BAM) Chapter 5 Salmonella reference method for wet dog food following the current AOAC guidelines. A total of 20 laboratories participated. For the 3M MDA Salmonella method, raw ground beef was analyzed using 25 g test portions, and wet dog food was analyzed using 375 g test portions. For the reference methods, 25 g test portions of each matrix were analyzed. Each matrix was artificially contaminated with Salmonella at three inoculation levels: an uninoculated control level (0 CFU/test portion), a low inoculum level (0.2-2 CFU/test portion), and a high inoculum level (2-5 CFU/test portion). In this study, 1512 unpaired replicate samples were analyzed. Statistical analysis was conducted according to the probability of detection (POD). For the low-level raw ground beef test portions, the following dLPOD (difference between the POD of the reference and candidate method) values with 95% confidence intervals were obtained: -0.01 (-0.14, +0.12). For the low-level wet dog food test portions, the following dLPOD with 95% confidence intervals were obtained: -0.04 (-0.16, +0.09). No significant differences were observed in the number of positive

  20. Third molar maturity index (I3M) for assessing age of majority in a black African population in Botswana.

    Science.gov (United States)

    Cavrić, Jelena; Galić, Ivan; Vodanović, Marin; Brkić, Hrvoje; Gregov, Jelena; Viva, Serena; Rey, Laura; Cameriere, Roberto

    2016-07-01

    Assessment of legal age, also known as age of majority, is a controversial issue as there are few body biomarkers or evidence during late adolescence differentiating a subject from being a minor or adult. The third molar was recognized as a suitable site for age examination in late adolescence. We analyzed the development of the left mandibular third molar by the third molar maturity index (I3M) and a specific cut-off value of I3M = 0.08, established by Cameriere et al. in 2008 and used it for discriminating between minors and adult black Africans from Gaborone, Botswana. A final sample of panoramic radiographs (OPTs) of 1294 people (582 males and 712 females) aged between 13 and 23 years was evaluated. The real age decreased as I3M gradually increased. There was no statistically significant difference in the third molar development evaluated using I3M between males and females (p > 0.05) across different I3M classes. Results of 2 × 2 contingency tables for different cut-off values indicated that I3M = 0.08 was useful in discriminating between adults and minors. Precisely, for I3M = 0.08, the values of accuracy or overall fraction of correctly classified were 0.91 in males with a 95 % confidence interval (95 % CI) of 0.88 to 0.93 and 0.92 (95 % CI, 0.90 to 0.93) in females. Values of sensitivity of the test or the proportion of participants being 18 years and older were 0.88 (95 % CI, 0.87 to 0.90) in males and 0.88 (95 % CI, 0.90 to 0.93) in females, while values of specificity or proportion of individuals younger than 18 who have I3M age of 18 years in Botswana. Further studies should address the usefulness of this method and specific cut-off for different adolescent populations.

  1. SF3M 2.0: improvement of 3D photo-reconstruction interface based on freely available software

    Science.gov (United States)

    Castillo, Carlos; James, Michael R.; Pérez, Rafael; Gómez, Jose A.

    2016-04-01

    During recent years, a number of tools based on Structure-from-Motion algorithms have been released for full image-based 3D reconstruction either freely (e.g. Bundler, PMVS2, VisualSFM, MicMac) or commercially (e.g. Agisoft PhotoScan). The SF3M interface was developed in Matlab® to use link software developments (VisualSFM, CloudCompare) and new applications to create a semi-automated workflow including reconstruction, georeferencing and point-cloud filtering, and has been tested for gully erosion assessment with terrestrial images (Castillo et al., 2015). The main aim of this work to provide an improved freely-available and easy-to-use alternative for 3D reconstruction intended for public agencies, non-profit organisations, researchers and other stakeholders interested in 3D modelling. In this communication we present SF3M 2.0, a new version of the graphical user interface. In this case, the SfM module is based on MicMac, an open-software tool (Pierrot-Deseilligny and Cléry, 2011) which provides advanced features such as camera calibration and constrained bundle adjustment using ground control points. SF3M 2.0 will be tested in two scenarios: a) using the same ground-based image set tested in Castillo et al. (2015) to compare the performance of both versions and b) using aerial images taken from a helium balloon to assess a gully network in a 40-hectares catchment. In this study we explore the advantages of SF3M 2.0, explain its operation and evaluate its accuracy and performance. This tool will be also available for free download. References Castillo, C., James, M.R., Redel-Macías, M. D., Pérez, R., and Gómez, J.A.: SF3M software: 3-D photo-reconstruction for non-expert users and its application to a gully network, SOIL, 1, 583-594. Pierrot-Deseilligny, M and Cléry, I. APERO, an Open Source Bundle Adjusment Software for Automatic Calibration and Orientation of a Set of Images. Proceedings of the ISPRS Commission V Symposium, Image Engineering and Vision

  2. Apuntes sobre encuestas electorales

    Directory of Open Access Journals (Sweden)

    Luis Benavente Gianella

    2013-12-01

    Full Text Available Las encuestas preelectorales suelen despertar gran interés por el valor predictivo que se les puede atribuir o que puedan tener, y por el efecto que puedan generar en los votantes. También se usan como herramienta efectiva para el manejo de las campañas de los candidatos. Existen tres tipos de encuestas electorales: preelectorales, boca de urna y postelectorales, en cada caso cumplen funciones diferentes en relación con los procesos electorales. Philippe Maarek (1 considera que la publicación de encuestas preelectorales influye en la decisión de voto mediante efectos directos e indirectos. Es en coyunturas preelectorales cuando las encuestas suelen concitar la mayor atención, especialmente por el valor predictivo que se les puede atribuir o que puedan tener, y por el efecto que puedan generar en los votantes, de manera especial en los indecisos, que constituyen un porcentaje usualmente muy alto durante casi toda la etapa preelectoral. Esto hace que las encuestas sean controvertidas y discutidas en el mundo. En los procesos electorales, las encuestas también son utilizadas como una herramienta efectiva para el manejo eficiente de las campañas de los candidatos, asumiendo de esta manera un papel protagónico y permanente en las campañas. Además de sus implicancias electorales, las encuestas tienen asimismo presencia en la vida política institucional en épocas no electorales. Actualmente son utilizadas para conocer la opinión de los ciudadanos acerca de diversos temas políticos, económicos y sociales. Las encuestadoras realizan sondeos periódicos sobre todos estos aspectos que son difundidos a través de los medios de comunicación, alimentando de este modo el debate político. En la actualidad, las encuestas de opinión son una práctica habitual en todos los países con regímenes democráticos, constituyéndose en un instrumento de medición de la opinión de los ciudadanos.

  3. Bolt study - behaviour of bolts in drop accident scenarios of the Nirex 3m{sup 3} Box ILW package

    Energy Technology Data Exchange (ETDEWEB)

    Turner, G. [United Kingdom Nirex Ltd., Harwell (United Kingdom); Tso, C.F. [Arup, London (United Kingdom)

    2004-07-01

    The mission of Nirex is to provide the UK with safe, environmentally sound and publicly acceptable options for the long-term management of radioactive materials. One of the key tasks is to ensure that waste is packaged by waste producers in a form which is suitable for safe storage, transport, handling and potential disposal. In pursuit of this key requirement, Nirex has developed specifications to set the standard for the design and performance of waste packages, and has developed standard containers for the packaging of intermediate level (ILW) and some low level waste (LLW) - one of these is the 3m{sup 3} Box for immobilised operational and decommissioning ILW. The dimension envelope of this package is 1716 mm x 1716 mm in plan with 430 mm corner radii, 1226 mm tall. The maximum loaded weight is 12 tonnes. A generic design of this container has been developed, which is a welded structure manufactured from austenitic stainless steel (EN 10088-2 steel number 1.4404). The lid is connected to the body by 28 stainless steel bolts. An extensive study was carried out to develop a robust FE model of the bolts. The specific focus of this work was to use improved bolt modelling to optimize the design of the 3m{sup 3} Box, although this work could be applied to other bolted containers. This paper presents a summary of the findings from the study as follows: 1. Development of a FE bolt model for application in a 3m{sup 3} Box model. 2. Development and execution of a bolt testing programme which included tensile and shear tests on a total of 88 bolts, representing four grades of stainless steel materials, three thread sizes, and two geometries at three strain rates. 3. Benchmarking of the FE bolt model that can be used with confidence in simulating waste package behaviour in drop scenarios.

  4. Bolt study - behaviour of bolts in drop accident scenarios of the Nirex 3m{sup 3} Box ILW package

    Energy Technology Data Exchange (ETDEWEB)

    Turner, G. [United Kingdom Nirex Ltd., Harwell (United Kingdom); Tso, C.F. [Arup, London (United Kingdom)

    2004-07-01

    The mission of Nirex is to provide the UK with safe, environmentally sound and publicly acceptable options for the long-term management of radioactive materials. One of the key tasks is to ensure that waste is packaged by waste producers in a form which is suitable for safe storage, transport, handling and potential disposal. In pursuit of this key requirement, Nirex has developed specifications to set the standard for the design and performance of waste packages, and has developed standard containers for the packaging of intermediate level (ILW) and some low level waste (LLW) - one of these is the 3m{sup 3} Box for immobilised operational and decommissioning ILW. The dimension envelope of this package is 1716 mm x 1716 mm in plan with 430 mm corner radii, 1226 mm tall. The maximum loaded weight is 12 tonnes. A generic design of this container has been developed, which is a welded structure manufactured from austenitic stainless steel (EN 10088-2 steel number 1.4404). The lid is connected to the body by 28 stainless steel bolts. An extensive study was carried out to develop a robust FE model of the bolts. The specific focus of this work was to use improved bolt modelling to optimize the design of the 3m{sup 3} Box, although this work could be applied to other bolted containers. This paper presents a summary of the findings from the study as follows: 1. Development of a FE bolt model for application in a 3m{sup 3} Box model. 2. Development and execution of a bolt testing programme which included tensile and shear tests on a total of 88 bolts, representing four grades of stainless steel materials, three thread sizes, and two geometries at three strain rates. 3. Benchmarking of the FE bolt model that can be used with confidence in simulating waste package behaviour in drop scenarios.

  5. Design and construction of 2 transonic airfoil models for tests in the NASA Langley C.3-M TCT

    Science.gov (United States)

    Schaechterle, G.; Ludewig, K. H.; Stanewsky, E.; Ray, E. J.

    1982-01-01

    As part of a NASA/DFVLR cooperation program two transonic airfoils were tested in the NASA Langley 0.3-m TCT. Model design and construction was carried out by DFVLR. The models designed and constructed performed extremely well under cryogenic conditions. Essentially no permanent changes in surface quality and geometric dimensions occurred during the tests. The aerodynamic results from the TCT tests which demonstrate the large sensitivity of the airfoil CAST 10-Z/DOAZ to Reynolds number changes compared well with results from other facilities at ambient temperatures.

  6. Extension of Studies with 3M Empore TM and Selentec MAG *SEP SM Technologies for Improved Radionuclide Field Sampling

    Energy Technology Data Exchange (ETDEWEB)

    Beals, D.M. [Westinghouse Savannah River Company, AIKEN, SC (United States); Bibler, J.P.; Brooks, D.A.

    1996-07-10

    The Savannah River Technology Center is evaluating new field sampling methodologies to more easily determine concentrations of radionuclides in aqueous systems. One methodology studied makes use of 3M EmporeTM disks. The disks are composed of selective resins embedded in a Teflon support. The disks remove the ion of interest from aqueous solutions when the solution is passed through the disk. The disk can then be counted directly to quantify the isotope of interest. Four types of disks were studied during this work: for the extraction of technetium (two types), cesium, plutonium, and strontium. A sampler has been developed for automated, unattended, in situ use of the EmporeTM disks.

  7. Nanocrystallization of the Fd3m Ti2Ni-type phase in Hf-based metallic glasses.

    Science.gov (United States)

    Louzguine, D V; Ko, M S; Ranganathan, S; Inoue, A

    2001-06-01

    Three ternary and four quaternary hafnium-based alloys have been rapidly solidified, and the devitrification of the resultant metallic glasses has been studied to evaluate the influence of composition on the products. The formation of metastable and stable Fd3m (Pearson symbol cF96) Ti2Ni was evident whenever the alloy composition in the stable equilibrium diagrams showed this phase. The replacement of nickel by iron led to the appearance of this phase in preference to the icosahedral quasicrystal. Several common features of the amorphous alloys that form either nanoscale icosahedral or cF96 Ti2Ni-type phases on devitrification are discussed and summarized.

  8. MRI of the lung using hyperpolarized He-3 at very low magnetic field (3 mT)

    CERN Document Server

    Bidinosti, C P; Tastevin, G; Vignaud, A; Nacher, P J

    2004-01-01

    Optical pumping of He-3 produces large (hyper) nuclear-spin polarizations independent of the magnetic resonance imaging (MRI) field strength. This allows lung MRI to be performed at reduced fields with many associated benefits, such as lower tissue susceptibility gradients and decreased power absorption rates. Here we present results of 2D imaging as well as accurate 1D gas diffusion mapping of the human lung using He-3 at very low field (3 mT). Furthermore, measurements of transverse relaxation in zero applied gradient are shown to accurately track pulmonary oxygen partial pressure, opening the way for novel imaging sequences.

  9. P3 mAb: An Immunogenic Anti-NeuGcGM3 Antibody with Unusual Immunoregulatory Properties

    OpenAIRE

    Martínez, Darel; Rodríguez, Nely; Griñán, Tania; Rondón, Teresa; Vázquez, Ana María; Pérez, Rolando; Hernández, Ana María

    2012-01-01

    P3 is a murine IgM mAb that recognize N-glycosylated gangliosides, sulfatides, and antigens expressed in melanoma, breast, and lung human tumors. This antibody has the ability to trigger an IgG antibody response in the syngeneic BALB/c model, even when it is administered in the absence of adjuvant or carrier protein. The mechanism by which the P3 mAb, a self-immunoglobulin, induce this immune response in the absence of co-stimulatory or classical danger signals is still unknown. In the presen...

  10. P3 mAb: an immunogenic anti-NeuGcGM3 antibody with unusual immunoregulatory properties.

    OpenAIRE

    Darel eMartínez; Nely eRodríguez; Tania eGriñán; Teresa eRondón; Ana María Vázquez1; Rolando ePérez; Ana María eHernández

    2012-01-01

    P3 is a murine IgM mAb that recognize N-glycolilated gangliosides, sulphatides and antigens expressed in melanoma, breast and lung human tumors. This antibody has the ability to trigger an IgG antibody response in the syngeneic BALB/c model, even when it is administered in the absence of adjuvant or carrier protein. The mechanism by which the P3 mAb, a self immunoglobuline, induce this immune response in the absence of co-stimulatory or classical danger signals is still unknown. In the presen...

  11. Synthesis of titanates MTiO{sub 3} (M = Mn, Co, Ni) by the sol-gel method

    Energy Technology Data Exchange (ETDEWEB)

    Moreno, J.; Tavizon, G.; Vicente, L. [UNAM, Mexico City (Mexico). Dept. de Fisica y Quimica Teorica; Viveros, T. [UAM-Iztapalapa, Mexico City (Mexico). Dept. de Ingenieria Quimica

    1996-12-31

    The titanates MTiO{sub 3} (M = Ni, Co, Mn) were prepared by a sol-gel method. The reaction between the metal solution and titanium butoxide leads to the formation of gels. The amorphous gels so obtained under different pH conditions, were calcined at temperatures between 750 C and 1,200 C to obtain in some cases high purity, crystalline MTiO{sub 3} powders. The characterization of the samples was done by X-ray powder diffraction, differential thermal analysis (DTA), thermal gravimetry (TG) and BET surface measurements.

  12. The Effect of Spray Strips on a Model of the P3M-1 Flying Boat Hull

    Science.gov (United States)

    Dawson, John R

    1933-01-01

    This note presents the results of a series of tests made in the N.A.C.A. tank on a one-sixth full-size model of the hull and side floats of the Navy P3M-1 flying boat for the purpose of finding a method of reducing the amount of spray thrown into the propellers of this craft when taking off and landing. The model was tested without spray strips and with five different spray-strip arrangements. The best arrangement was an improvement over the bare hull with no spray strips, but the improvement was not sufficient to be satisfactory with the propellers in the designed position.

  13. Determination of the scattering lengths of gallium isotopes by neutron interferometry with PNO-apparatus in JRR-3M

    Science.gov (United States)

    Tomimitsu, H.; Hasegawa, Y.; Aizawa, K.; Kikuta, S.

    1999-01-01

    For carrying out experiments in the field of the so-called precise neutron optics (PNO), we have implemented special multi-purpose apparatus called the "PNO-apparatus" at JRR-3M. Making use of an Si triple-Laue (LLL) neutron interferometer with the PNO-apparatus, we successfully determined the coherent neutron scattering lengths of gallium isotopes, 69Ga and 71Ga. The results are 8.053±0.013 fm for 69Ga and 6.170±0.011 fm for 71Ga, respectively.

  14. 3M: Hutchinson Plant Focuses on Heat Recovery and Cogeneration during Plan-Wide Energy-Efficiency Assessment

    Energy Technology Data Exchange (ETDEWEB)

    None

    2003-06-01

    3M performed a plant-wide energy efficiency assessment at its Hutchinson, Minnesota, plant to identify energy- and cost-saving opportunities. Assessment staff developed four separate implementation packages that represented various combinations of energy-efficiency projects involving chiller consolidation, air compressor cooling improvements, a steam turbine used for cogeneration, and a heat recovery boiler for two of the plant's thermal oxidizers. Staff estimated that the plant could save 6 million kWh/yr in electricity and more than 200,000 MMBtu/yr in natural gas and fuel oil, and avoid energy costs of more than $1 million during the first year.

  15. Photoelectron velocity-map imaging and theoretical studies of heteronuclear metal carbonyls MNi(CO)3- (M = Mg, Ca, Al)

    Science.gov (United States)

    Xie, Hua; Zou, Jinghan; Yuan, Qinqin; Fan, Hongjun; Tang, Zichao; Jiang, Ling

    2016-03-01

    The heteronuclear metal carbonyl anions MNi(CO)3- (M = Mg, Ca, Al) have been investigated using photoelectron velocity-map imaging spectroscopy. Electron affinities of neutral MNi(CO)3 (M = Mg, Ca, Al) are measured from the photoelectron spectra to be 1.064 ± 0.063, 1.050 ± 0.064, and 1.541 ± 0.040 eV, respectively. The C-O stretching mode in these three clusters is observed and the vibrational frequency is determined to be 2049, 2000, and 2041 cm-1 for MgNi(CO)3, CaNi(CO)3, and AlNi(CO)3, respectively. Density functional theory calculations are carried out to elucidate the geometric and electronic structures and to aid the experimental assignments. It has been found that three terminal carbonyls are preferentially bonded to the nickel atom in these heterobinuclear nickel carbonyls MNi(CO)3-1/0, resulting in the formation of the Ni(CO)3 motif. Ni remains the 18-electron configuration for MgNi(CO)3 and CaNi(CO)3 neutrals, but not for AlNi(CO)3. This is different from the homobinuclear nickel carbonyl Ni-Ni(CO)3 with the involvement of three bridging ligands. Present findings would be helpful for understanding CO adsorption on alloy surfaces.

  16. Hydrogeological and geochemical modeling of hydrothermal fluids circulation in active ultramafic-hosted systems under CAST3M

    Science.gov (United States)

    Perez, F.; Mugler, C.; Jean-Baptiste, P.; Charlou, J. L.; Donval, J.; Vidal, O.; Marcailloux, C.; Munoz, M.

    2010-12-01

    Hydrothermal circulation at mid-ocean ridges is a fundamental process that impacts the transfer of energy and water from the interior of the Earth to the Crust, Hydrosphere and biosphere. Along the Mid-Atlantic Ridge (MAR), at precisely located ultramafic-hosted systems, important fluxes of heat, hydrogen and Iron are observed (Charlou et al., 2010 AGU Monograph series). It is now demonstrated that high and low-temperature hydrothermal activity and mantle degassing are indicators of ongoing serpentinization process. For a real understanding of this process and to estimate heat and hydrogen fluxes, numerical modeling leant on field data and laboratory experiments can yield results of interest. We thus developed a thermo-hydrogeological numerical model using a Finite Volume method to simulate heat driven fluid flows in geological layers, encoded under CAST3M, and presented here. For homogeneous medias, we successfully obtained exiting fluid temperatures that natural hydrothermal fluids usually reach. Considering laboratory experiments, we coupled, under CAST3M, our thermo-hydrogeological model to a geochemical model of serpentinization reaction. This last model is based on a reaction front velocity model calibrated by laboratory experiments. Primary results are presented here.

  17. STUDY OF MORPHOLOGICAL CHANGES OF HEART IN VIRAL MYOCARDITIS CAUSED BY REPETITIVE INFECTION OF CVB3m

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Objective To investigate the morphological changes of heart in viral myocarditis caused by repetitive infection of CVB3m. Methods 4-week-old mice were infected four times intraperitoneally with a timedependent dose and killed at the 10th,30th and 60th day after the final infection respectively, then we examined the heart changes and collagen hyperplasia by HE, VG stain and IHC. Results Heart damage appeared very serious at the tenth day, even there were small necrotic foci at the day of 30th, but we could not see any injury of heart 2 months later after final infection. Collagen turned up at the tenth day and there was much more collagen in heart and increased PCVA, CVF index at the sixtieth day. The IHC of collagen demonstrated the collagen Ⅰ hyperplasia was much obvious compared to collagen Ⅲ. Conclusion It strongly indicated that repetitive infection of CVB3m could lead to heart fibrosis and ventricular remodeling, which resulted in decreased systolic and diastolic function of heart.

  18. Measurements of radiation exposure on commercial aircraft with the LIULIN-3M instrument; Mesure de l'exposition aux radiations sur les vols commerciaux avec l'equipement LIULIN-3M

    Energy Technology Data Exchange (ETDEWEB)

    Stassinopoulos, E.G. [NASA Centre des Vols Spatiaux Goddard, Greenbelt, MD (United States); Stauffer, C.A. [Stinger Gaffarian Technologies, Greenbelt, MD (United States); Dachev, T.P.; Tomov, B.T.; Dimitrov, P.G. [Academie des Sciences, Bulgarie, Lab. d' Etudes des Influences Soleil-Terre, Sofia (Bulgaria); Brucker, G.J. [Radiation Effects Consultants, Inc., West Long Branch, NJ (United States)

    1999-07-01

    The LIULIN-3M evolved from an international cooperative project by a group of Bulgarian, Russian, German, and American scientists. The radiometer is a low power, small size, light weight, and low cost instrument composed of a solid state detector (SSD) with supporting electronics that enable it to operate as a pulse height analyzer of energy deposited in the detector, and to obtain from these measurements the total dose or the dose rate produced by charged particles. The instrument has also been used as a low-LET radiation spectrometer for measuring biological doses of potential human exposures. A flash memory allows self-storage of data during flights and post flight retrieval. Results will be presented and discussed. (author)

  19. Historicismo: notas sobre um paradigma

    National Research Council Canada - National Science Library

    José D’Assunção Barros

    2012-01-01

    Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX...

  20. Acueducto pretensado sobre el Holme

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1958-04-01

    Full Text Available Breve descripción del paso de una canalización de 0,60 m de diámetro, destinada al abastecimiento de aguas, sobre el río Holme (Inglaterra. El puente formado tiene dos vigas de hormigón pretensado, cuyas armaduras se componen de barras McCall.

  1. Sobre Humanismo y Medicina

    Directory of Open Access Journals (Sweden)

    Adolfo de Francisco Zea

    2000-12-01

    Full Text Available

    En esta disertación sobre “Humanismo y Medicina”, título del libro que tuve ocasión de publicar hace un par de años, destacaré algunas de las relaciones que existen entre la medicina y las bellas artes, concretamente la música y la pintura. La Medicina tiene como objeto de su acción al Hombre. Definida como la ciencia y el arte de prevenir, curar o aliviar la enfermedad, no tiene como meta la simple prolongación de la vida biológica.

    Su tarea consiste en postergar la muerte, prevenir o reducir los padecimientos y las deformidades, curar las enfermedades, ampliar las capacidades biológicas y psicológicas de los seres humanos y ocuparse de los sufrimientos de las personas. Para Tristam Engelhardt, es la Medicina de las personas.

    Se concibe a la persona humana como el individuo de conciencia reflexiva normal que es a la vez miembro pleno de la comunidad, con los deberes y derechos que presuponen su pertenencia a ella. A esta acepción de carácter moral de la persona humana, que corresponde a lo que se llama persona “en sentido estricto”, se agrega la acepción social, que hace relación con aquellas personas a las que se otorgan prácticamente los mismos derechos, como es el caso de los niños, de los individuos que perdieron el carácter de personas por padecer de lesiones cerebrales o demencia, y de aquellos que nunca llegarán a serlo como los retrasados mentales profundos.

    Al sostener que no todos los seres humanos son personas “en sentido estricto”, la Bioética que expone Engelhardt impone, sin embargo, como obligación moral, tratar a estos últimos con pleno respeto y comprensión. Lo que es importante acerca de nosotros mismos como seres humanos, es el hecho real de que seamos personas; no simplemente nuestra pertenencia al género Horno sapiens como tal.

    Para Víctor Frankl, la persona humana es de carácter espiritual y en tal virtud, es diferente del organismo psicofísico cuya

  2. Phycocyanin for protecting brain ischemia-reperfusion injury and its effect on the expression of Caspase-3 mRNA

    Institute of Scientific and Technical Information of China (English)

    Xuewei Yang; Yunliang Guo; Hongbing Chen

    2006-01-01

    BACKGROUND: Phycocyanin can anti-oxidize and clear free radial. Whether its protective effect on brain is related to Caspase-3, the promoter and operator of apoptosis, is highly concerned.OBJECTIVE: To observe phycocyanin for protecting nerve function and reducing the size of cerebral infarction of rats with brain ischemia-reperfusion and its effect on the expression of Caspase-3 mRNA.DESIGN: A randomized controlled experiment.SETrING: Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University.MATERIALS: Totally 84 adult healthy female Wistar rats, weighing 210 to 250 g, of clean grade, were provided by the Animal Experimental Center of Shandong University. Phycocyanin (Institute of Oceanography of Chinese Academy of Sciences) was used.METHODS: This experiment was carried out in the Key Laboratory for Prevention and Treatment of Brain Diseases during May to December 2005. ① The rats were randomized into sham-operation group (n=4),control group (n=40) and phycocyanin-treated group (n=40). Middle cerebral artery occlusion/reperfusion (MACO/R) models were created on the rats of control and phycocyanin-treated groups with suture-occluded method by inserting a thread into left side external-internal carotid artery. In the sham-operation group, inserting suture was omitted. After ischemia for 1 hour and reperfusion for 2 hours, suspension of phycocyanin was intragastrically administrated into the rats of the phycocyanin-treated group at 100 mg/kg , and the same volume of normal saline was isochronously administrated into the rats of control group as the same. ② Six rats were chosen respectively from the control group and phycocyanin-treated group, then neurologic impairment degrees of rats were evaluated according to Bederson's grading. ③ Six rats were chosen respectively from the control and phycocyanin-treated groups. The isolated brain tissue was stained with triphenyltetrazolium chloride, and then the size of cerebral

  3. Evaluation of the 3M Petrifilm Enterobacteriaceae Count plate method for the enumeration of Enterobacteriaceae in foods.

    Science.gov (United States)

    Silbernagel, Karen M; Lindberg, Kathryn G

    2002-09-01

    Results of the 3M Petrifilm Enterobacteriaceae Count (EB) plate method were compared with those of the standard violet red bile glucose agar (VRBG) method for the detection and enumeration of Enterobacteriaceae. Studies involving 107 bacterial strains demonstrated that the Petrifilm EB plate method is as sensitive as and more selective than the VRBG method. Sixty of the 62 pure Enterobacteriaceae cultures were recovered by both methods. In addition, 38 of the 45 non-Enterobacteriaceae organisms did not grow on the Petrifilm EB plate, while 28 of the 45 non-Enterobacteriaceae organisms did not grow on the VRBG plate. Colony counts from 174 naturally contaminated and 120 artificially inoculated dairy and nondairy food samples showed that the Petrifilm EB plate method performed as well as or better than the standard VRBG method for the enumeration of Enterobacteriaceae.

  4. Trends in (LaMnO3)n/(SrTiO3)m superlattices with varying layer thicknesses

    KAUST Repository

    Jilili, J.

    2015-09-01

    We investigate the thickness dependence of the structural, electronic, and magnetic properties of (LaMnO3)n/(SrTiO3)m (n, m = 2, 4, 6, 8) superlattices using density functional theory. The electronic structure turns out to be highly sensitive to the onsite Coulomb interaction. In contrast to bulk SrTiO3, strongly distorted O octahedra are observed in the SrTiO3 layers with a systematic off centering of the Ti atoms. The systems favour ferromagnetic spin ordering rather than the antiferromagnetic spin ordering of bulk LaMnO3 and all show half-metallicity, while a systematic reduction of the minority spin band gaps as a function of the LaMnO3 and SrTiO3 layer thicknesses originates from modifications of the Ti dxy states.

  5. Dry rehydratable film method for rapid enumeration of coliforms in foods (3M Petrifilm Rapid Coliform Count plate): collaborative study.

    Science.gov (United States)

    Kinneberg, Karen M; Lindberg, Kathryn G

    2002-01-01

    A rehydratable dry-film plating method for coliforms in foods, the 3M Petrifilm Rapid Coliform Count plate method, was compared with the U.S. Food and Drug Administration's Bacteriological Analytical Manual method for nondairy foods and the American Public Health Association's Standard Methods for the Examination of Dairy Products (SMEDP) method for dairy foods. Six food types, vanilla ice cream, cheddar cheese, fresh refrigerated uncooked pasta, wheat flour, prepared frozen macaroni and cheese, and frozen hash browns, were analyzed for coliforms by 11 collaborating laboratories. For each food product tested, the collaborators received 8 blind samples consisting of a control sample and 3 levels of inoculated sample, each in duplicate. The mean log counts for the methods were comparable. The repeatability and reproducibility variances of the Petrifilm Rapid Coliform Count method at 14 and 24 h were not significantly different from those of the standard methods.

  6. 3M Petrifilm Staph Express Count plate method for the enumeration of Staphylococcus aureus in selected dairy foods: collaborative study.

    Science.gov (United States)

    Silbernagel, Karen M; Jechorek, Robert P; Carver, Charles N; Horter, Barbara L; Lindberg, Kathryn G

    2003-01-01

    The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Five foods--ice cream, raw milk, yogurt, whey powder, and cheese--were analyzed for S. aureus by 12 collaborating laboratories. For each food tested, the collaborators received 8 blind test samples consisting of a control sample, a low inoculation level, a medium inoculation level, and a medium inoculation level with background flora, each in duplicate. The mean log10 counts for the methods were comparable for all 5 foods. The repeatability and reproducibility variances of the 24 h Petrifilm Staph Express Count plate method were similar to those of the 72 h standard method.

  7. Characteristics of the three-half-turn-antenna-driven RF discharge in the Uragan-3M torsatron

    Energy Technology Data Exchange (ETDEWEB)

    Grigor’eva, L. I.; Chechkin, V. V., E-mail: chechkin@ipp.kharkov.ua; Moiseenko, V. E.; Grekov, D. L.; Pavlichenko, R. O.; Lozin, A. V.; Tarasov, I. K.; Kulaga, A. Ye.; Zamanov, N. V.; Tretiak, K. K.; Kozulya, M. M.; Beletskii, A. A.; Kasilov, A. A.; Mironov, Yu. K.; Romanov, V. S.; Voitsenya, V. S. [National Science Center Kharkiv Institute of Physics and Technology, Institute of Plasma Physics (Ukraine)

    2015-12-15

    In the ℓ = 3 Uragan-3M torsatron hydrogen plasma is produced by RF fields in the Alfvén range of frequencies (ω ≤ ω{sub ci}). The initial (target) plasma with the line-averaged density of units 10{sup 12} cm{sup −3} is produced by a frame antenna with a broad spectrum of generated parallel wavenumbers. After this, to heat the plasma and bring its density to ∼10{sup 13} cm{sup –3}, another, shorter wavelength three-half-turn antenna with large transverse currents is used. The behavior of the density, electron temperature, and loss of the plasma supported by the three-half-turn antenna is studied depending on the RF power fed to the antenna and initial values of the density and electron temperature supplied by the frame antenna.

  8. Nonlinear elastic properties of superconducting antiperovskites MNNi 3 (M =Zn, Cd, Mg, Al, Ga, and In) from first principles

    KAUST Repository

    Liu, Lili

    2014-05-22

    We present theoretical studies for the third-order elastic constants (TOECs) of superconducting antiperovskites MNNi 3 (M = Zn, Cd, Mg, Al, Ga, and In) using the density functional theory (DFT) and homogeneous deformation method. From the nonlinear least-square fitting, the elastic constants are extracted from a polynomial fit to the calculated strain-energy data. Calculated second-order elastic constants (SOECs) are compared with the previous theoretical calculations, and a very good agreement was found. The nonlinear effects often play an important role when the finite strains are larger than approximately 2.5 %. Besides, we have computed the pressure derivatives of SOECs and provided rough estimations for the Grüneisen constants of long-wavelength acoustic modes by using the calculated TOECs. © 2014 Springer Science+Business Media New York.

  9. Piezoelectric Enhancement of (PbTiO3)m/(BaTiO3)n Ferroelectric Superlattices through Domain Engineering

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Liang; Wu, Pingping; Li, Yulan; Gopalan, Venkatraman; Eom, C.B.; Schlom, Darrell G.; Chen, Long-Qing

    2014-11-20

    The phase diagram of (PbTiO3)m/(BaTiO3)n ferroelectric superlattices was computed using the phase-field approach as a function of layer volume fraction and biaxial strain to tune ferroelectric properties through domain engineering. Two interesting domain structures are found: one with mixed Bloch-Néel-Ising domain wall structures and the other with stabilized monoclinic phases. The polarization of the monoclinic phase is able to rotate from out-of-plane to in-plane or vice versa under an electric field, and thus facilitates the domain reversal of rhombohedral domains. This contributes significantly to both reduced coercive fields and enhanced piezoelectric responses.

  10. First-principles study of mechanical stability and thermal properties of MNNi3 (M=Zn, Mg, Al) under pressure

    Institute of Scientific and Technical Information of China (English)

    Zhai Hong-Cun; Li Xiao-Feng; Du Jun-Yi; Ji Guang-Fu

    2012-01-01

    The mechanical stability,elastic,and thermodynamic properties of the anti-perovskite superconductors MNNi3(M=Zn,Mg,Al)are investigated by means of the first-principles calculations.The calculated structural parameters and elastic properties of MNNi3 are in good agreement with the experimental and the other theoretical results.From the elastic constants under high pressure,we predict that ZnNNi3,MgNNi3,and AlNNi3 are not stable at the pressures above 61.2 GPa,113.3 GPa,and 122.4 GPa,respectively.By employing the Debye model,the thermodynamic properties,such as the heat capacity and the thermal expansion coefficient,under pressures and at finite temperatures are also obtained successfully.

  11. About improving efficiency of the P3 M algorithms when computing the inter-particle forces in beam dynamics

    Science.gov (United States)

    Kozynchenko, Alexander I.; Kozynchenko, Sergey A.

    2017-03-01

    In the paper, a problem of improving efficiency of the particle-particle- particle-mesh (P3M) algorithm in computing the inter-particle electrostatic forces is considered. The particle-mesh (PM) part of the algorithm is modified in such a way that the space field equation is solved by the direct method of summation of potentials over the ensemble of particles lying not too close to a reference particle. For this purpose, a specific matrix ;pattern; is introduced to describe the spatial field distribution of a single point charge, so the ;pattern; contains pre-calculated potential values. This approach allows to reduce a set of arithmetic operations performed at the innermost of nested loops down to an addition and assignment operators and, therefore, to decrease the running time substantially. The simulation model developed in C++ substantiates this view, showing the descent accuracy acceptable in particle beam calculations together with the improved speed performance.

  12. Combinatorial cytotoxic effects of Curcuma longa and Zingiber officinale on the PC-3M prostate cancer cell line

    Science.gov (United States)

    Kurapati, Kesava Rao V.; Samikkannu, Thangavel; Kadiyala, Dakshayani B.; Zainulabedin, Saiyed M.; Gandhi, Nimisha; Sathaye, Sadhana S.; Indap, Manohar A.; Boukli, Nawal; Rodriguez, Jose W.; Nair, Madhavan P.N.

    2015-01-01

    Background Many plant-derived products exhibit potent chemopreventive activity against animal tumor models as well as rodent and human cancer cell lines. They have low side effects and toxicity and presumably modulate the factors that are critical for cell proliferation, differentiation, senescence and apoptosis. The present study investigates the effects of some medicinal plant extracts from generally recognized as safe plants that may be useful in the prevention and treatment of cancer. Methods Clonogenic assays using logarithmically-growing cells were performed to test the effect. The cytotoxic effects of Curcuma longa and Zingiber officinale were studied using sulforhodamine B assay, tetrazolium dye assay, colony morphology and microscopic analysis. Results Out of the 13 lyophilized plant-derived extracts evaluated for growth-inhibitory effects on the PC-3M prostate cancer cell line, two extracts derived from C. longa and Z. officinale showed significant inhibitory effects on colony-forming ability. The individual and augmentative effects of these two extracts were tested for their narrow range effective lower concentration on PC-3M in clonogenic assays. At relatively lower concentrations, C. longa showed significant inhibition of colony formation in clonogenic assays; whereas at same concentrations Z. officinale showed only moderate inhibitory effects. However, when both the agents were tested together at the same concentrations, the combined effects were much more significant than their individual ones. On normal prostate epithelial cells both C. longa and Z. officinale had similar effects but at a lower magnitude. These observations were confirmed by several cytotoxicity assays involving the morphological appearance of the colonies, microscopic observations, per cent inhibition in comparison to control by sulforhodamine B and tetrazolium dye assay. Conclusions From these observations, it was concluded that the combined effects of C. longa and Z. officinale

  13. Overview of the O3M SAF GOME-2 operational atmospheric composition and UV radiation data products and data availability

    Directory of Open Access Journals (Sweden)

    S. Hassinen

    2015-07-01

    Full Text Available The three GOME-2 instruments will provide unique and long data sets for atmospheric research and applications. The complete time period will be 2007–2022, including the period of ozone depletion as well as the beginning of ozone layer recovery. Besides ozone chemistry, the GOME-2 products are important e.g. for air quality studies, climate modeling, policy monitoring and hazard warnings. The heritage for GOME-2 is in the ERS/GOME and Envisat/SCIAMACHY instruments. The current Level 2 (L2 data cover a wide range of products such as trace gas columns (NO2, BrO, H2CO, H2O, SO2, tropospheric columns of NO2, total ozone columns and vertical ozone profiles in high and low spatial resolution, absorbing aerosol indices from the main science channels as well as from the polarization channels (AAI, AAI-PMD, Lambertian-equivalent reflectivity database, clear-sky and cloud-corrected UV indices and surface UV fields with different weightings and photolysis rates. The Ozone Monitoring and Atmospheric Composition Satellite Application Facility (O3M SAF processing and data dissemination is operational and running 24/7. Data quality is quarantined by the detailed review processes for the algorithms, validation of the products as well as by a continuous quality monitoring of the products and processing. This is an overview paper providing the O3M SAF project background, current status and future plans to utilization of the GOME-2 data. An important focus is the provision of summaries of the GOME-2 products including product principles and validation examples together with the product sample images. Furthermore, this paper collects the references to the detailed product algorithm and validation papers.

  14. An experimental AWTS process and comparisons of ONERA T2 and 0.3-m TCT AWTS data for the ONERA CAST-10 aerofoil

    Science.gov (United States)

    Wolf, Stephen; Jenkins, Renaldo

    1989-01-01

    An experimental Adaptive Wall Test Section (AWTS) process is described. Comparisons of the ONERA T2 and the 0.3-m TCT (transonic cryogenic tunnel) AWTS data for the ONERA CAST-10 airfoil are presented. Most of the 0.3-m TCT data is new and preliminary and no sidewall boundary layer control is involved. No conclusions are given.

  15. Study on Catalytic Combustion of VOCs over LaMO3 (M = Co, Mn) Perovskite Catalysts%LaMO3(M=Co,Mn)钙钛矿型催化剂上VOCs催化燃烧的研究

    Institute of Scientific and Technical Information of China (English)

    黄海凤; 唐伟; 陈银飞; 陈碧芬

    2004-01-01

    研究了LaMO3(M=Co,Mn)钙钛矿型催化剂对VOCs的催化燃烧性能,该类催化剂对单一VOC和混合VOCs均有很好的催化活性,而LaMnO3的催化活性要比LaCoO3的催化活性更好,氧化还原滴定实验表明,LaMnO3催化剂中锰以Mn4+(大约35%)和Mn3+价态存在,而在LaCoO3催化剂中发现钴均以Co3+价态存在;在混合VOCs催化燃烧的试验中,3种有机物的易氧化性依次为正丙醇>甲苯>环己烷,达到99%的转化率时,环己烷的反应温度则比甲苯的反应温度要约低40℃.

  16. Breve informe sobre la coca

    Directory of Open Access Journals (Sweden)

    Lauro Hinostroza García

    1985-12-01

    Full Text Available El presente informe se integra en la investigación dirigida por el doctor Juan Ossio, por encargo de la Organización de los Estados Americanos (O.E.A. sobre “EFECTOS SOCIALES, CULTURALES, MÉDICOS Y ECONÓMICOS DEL USO TRADICIONAL DE LA COCA EN POBLACIONES DEL ANTIPLANO Y SIERRA DEL PERÚ, EN ESPECIAL DE LAS POBLACIONES INDÍGENAS”. Expone tópicos sobre la hoja de coca en la cultura andina: criterios clasificatorios, mitos, canciones y una muestra de qatipay o seguimiento. Este último es una práctica ritual importante para el campesinado andino, orienta el presente, pasado y futuro de toda su actividad. Cada hoja, por su forma, posición y tamaño, develará los roles sociales que ha de asumir, es decir los misterios del tiempo.

  17. Sobre la verdad en periodismo

    Directory of Open Access Journals (Sweden)

    Julio Estremadoyro Alegre

    2011-05-01

    Full Text Available Cuando un periodista informa sobre un desastre natural, con granpérdida de vidas, las autoridades y las fuentes de primera manodan cifras que son difundidas como verdades del suceso. Sinembargo, y la experiencia lo confirma, al día siguiente la cifraspueden haber cambiado y, por lo tanto, la verdad informativa esotra. Y así, sucesivamente, cada día habrá novedades y nuevas cifras verdaderas.

  18. Patterns of mouse reticulon 3 mRNA and protein expression in the mouse central nervous system

    Institute of Scientific and Technical Information of China (English)

    LIU Jin; QIANG Boqin; YUAN Jiangang; HUANG Xiaowei; PENG Xiaozhong; YANG Hongbo; YIN Bin; TAN Xinyu; FAN Ming; FAN Wenhong; LIU Bingyan

    2003-01-01

    Reticulons (RTN) are endoplasmic reticulumassociated protein complexes, which are localized in the endoplasmic reticulum (ER) and identified as markers for neuroendocrine differentiation. At least four different RTN genes have been identified in mammals, but in most cases,the functions of the encoded proteins except mammalian RTN4-A and RTN4-B are still elusive. In the present study,mouse reticulon 3 (mRTN3) is cloned and its expression pattern in a variety of tissues is investigated. Three alternatively spliced transcripts of 1.8, 2.8 and 4.2 kb are revealed by Northern blotting hybridization. The 1.8 and 2.8 kb transcripts are expressed in many tissues. The 2.8 kb transcript has a high level in brain and the 4.2 kb transcript is only found in brain. In situ hybridization and immunohistochemical analysis indicated its high expression in non-glial cells in some particular region of mouse central nervous system, such as hippocampus, sub-thalamus nucleus, thalamus nucleus and cerebrum cortex.

  19. Effect of ring rotation upon gas adsorption in SIFSIX-3-M (M = Fe, Ni) pillared square grid networks

    Energy Technology Data Exchange (ETDEWEB)

    Elsaidi, Sameh K.; Mohamed, Mona H.; Simon, Cory M.; Braun, Efrem; Pham, Tony; Forrest, Katherine A.; Xu, Wenqian; Banerjee, Debasis; Space, Brian; Zaworotko, Michael J.; Thallapally, Praveen K.

    2017-01-01

    The study of the mobility/rotation of the organic linkers in porous metal-organic frameworks could provide a valuable information about the guest/framework interaction and the factors control the kinetics of adsorption. Here, we analyzed the dynamics of pyrazine ring rotation in a series of pillared square grid frameworks, namely SIFSIX-3-M (M = Fe, Ni). It was found that the rotation of pyrazine ring is influenced by the variation of metal cation, temperature and the guest molecule. The Fe-analogue, [Fe(pz)2(SiF6)2] (pz= Pyrazine), , showed no pronounced ring rotation and exhibited a high affinity toward Xe gas over Kr as exemplified by the sharp Xe uptake at low loading (~0.1 bar) and its high isosteric heat of adsorption (Qst~ 27.4 kJmol-1) compared to the current benchmark materials. The Ni analogue, on the contrary, showed a two-regime adsorption isotherm for Xe with a temperature-dependent inflection point. However, this behavior is not observed with the other gases such as CO2, N2, and Kr which showed one-step adsorption isotherms without any inflection. Using molecular models and simulations, we hypothesize that the inflection point is due to a disordered to ordered transition of the rotational configurations of the pz rings in SIFSIX-3-Ni. These results further support the impact of tuning the pore size and chemistry on the adsorption behavior of porous materials.

  20. Residual strain measurements of a fatigued metal stick and heat treated steel pipe at JRR3M-RESA

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Kazuko; Horikawa, Takeshi; Kawashima, Hisaichi [Ryukoku Univ., Kyoto (Japan); Minakawa, Nobuaki; Tsuchiya, Yoshinori

    1997-06-01

    A residual strain on section of notched edge after fatiguing the carbon steel round bar with ring shape and semi-circular section and on thick direction of 13% Cr-steel pipe for oil well heat-treated after machining was tried to test. It was one of the initial experiments in residual strain measurement apparatus (RESA; old name is DIVE) installed at T2-1 port of JRR-3M to test a residual strain at section of 8 mm in diameter of the fatigue specimen at three (x{sup -}, y{sup -} and z{sup -}) directions on a fine mesh of 1 mm step. This test has another aim to inspect the apparatus itself such as obtained accuracy, required testing time, and so on, except original aim to find out strain of the specimen. As a result of the initial experiment, a lot of points to be investigated and improved were found out. According to these results, at present a fatigue specimen with large diameter (40 mm) is now in preparation. And, as is now processing on improvement of a monochromator to increase the beam intensity and so on, a higher resolution as well as a finer (about 1 micron) beam diameter for the specimen is expected to establish. (G.K.)

  1. Calculation of design load for the MOD-5A 7.3 mW wind turbine system

    Science.gov (United States)

    Mirandy, L.; Strain, J. C.

    1995-01-01

    Design loads are presented for the General Electric MOD-SA wind turbine. The MOD-SA system consists of a 400 ft. diameter, upwind, two-bladed, teetered rotor connected to a 7.3 mW variable-speed generator. Fatigue loads are specified in the form of histograms for the 30 year life of the machine, while limit (or maximum) loads have been derived from transient dynamic analysis at critical operating conditions. Loads prediction was accomplished using state of the art aeroelastic analyses developed at General Electric. Features of the primary predictive tool - the Transient Rotor Analysis Code (TRAC) are described in the paper. Key to the load predictions are the following wind models: (1) yearly mean wind distribution; (2) mean wind variations during operation; (3) number of start/shutdown cycles; (4) spatially large gusts; and (5) spatially small gusts (local turbulence). The methods used to develop statistical distributions from load calculations represent an extension of procedures used in past wind programs and are believed to be a significant contribution to Wind Turbine Generator analysis. Test/theory correlations are presented to demonstrate code load predictive capability and to support the wind models used in the analysis. In addition MOD-5A loads are compared with those of existing machines. The MOD-5A design was performed by the General Electric Company, Advanced Energy Program Department, under Contract DEN3-153 with NASA Lewis Research Center and sponsored by the Department of Energy.

  2. The Horizontal Branch in the UV Colour Magnitude Diagrams. II. The case of M3, M13 and M79

    CERN Document Server

    Dalessandro, Emanuele; Ferraro, Francesco R; Mucciarelli, Alessio; Cassisi, Santi

    2012-01-01

    We present a detailed comparison between far-UV/optical colour Magnitude Diagrams obtained with high-resolution Hubble Space Telescope data and suitable theoretical models for three Galactic Globular Clusters: M3, M13 and M79. These systems represents a classical example of clusters in the intermediate metallicity regime that, even sharing similar metal content and age, show remarkably different Horizontal Branch morphologies. As a consequence, the observed differences in the colour distributions of Horizontal Branch stars cannot be interpreted in terms of either first (metallicity) or a second parameter such as age. We investigate here the possible role of variations of initial Helium abundance (Y). Thanks to the use of a proper setup of far-UV filters, we are able to put strong constraints on the maximum Y (Y_{max}) values compatible with the data. We find differences Delta Y_{max} ~ 0.02-0.04 between the clusters with M13 showing the largest value (Y_{max} ~ 0.30) and M3 the smallest (Y_{max} ~ 0.27). In g...

  3. De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly.

    Science.gov (United States)

    Lee, Jeong Ho; Huynh, My; Silhavy, Jennifer L; Kim, Sangwoo; Dixon-Salazar, Tracy; Heiberg, Andrew; Scott, Eric; Bafna, Vineet; Hill, Kiley J; Collazo, Adrienne; Funari, Vincent; Russ, Carsten; Gabriel, Stacey B; Mathern, Gary W; Gleeson, Joseph G

    2012-06-24

    De novo somatic mutations in focal areas are well documented in diseases such as neoplasia but are rarely reported in malformation of the developing brain. Hemimegalencephaly (HME) is characterized by overgrowth of either one of the two cerebral hemispheres. The molecular etiology of HME remains a mystery. The intractable epilepsy that is associated with HME can be relieved by the surgical treatment hemispherectomy, allowing sampling of diseased tissue. Exome sequencing and mass spectrometry analysis in paired brain-blood samples from individuals with HME (n = 20 cases) identified de novo somatic mutations in 30% of affected individuals in the PIK3CA, AKT3 and MTOR genes. A recurrent PIK3CA c.1633G>A mutation was found in four separate cases. Identified mutations were present in 8-40% of sequenced alleles in various brain regions and were associated with increased neuronal S6 protein phosphorylation in the brains of affected individuals, indicating aberrant activation of mammalian target of rapamycin (mTOR) signaling. Thus HME is probably a genetically mosaic disease caused by gain of function in phosphatidylinositol 3-kinase (PI3K)-AKT3-mTOR signaling.

  4. Deposition of LaMO 3 (M=Co, Cr, Al) films by spray pyrolysis in inductively coupled plasma

    Science.gov (United States)

    Ichinose, Hiromichi; Katsuki, Hiroaki; Nagano, Masamitsu

    1994-11-01

    LaMO 3 (M=Co, Cr, Al) films were prepared on substrates by introducing ultrasonically atomized metal nitrate solutions into an inductively coupled plasma under atmospheric pressure (spray-ICP technique). Dense perovskite-type oxide films of LaCoO 3 and LaCrO 3 were obtained at 600-900°C, while the LaAiO 3 films consisted of loosely packed aggregates. Deposition rates of the films were 6-35 nm/min at 600-900°C. The high temperature phases (cubic) of LaCoO 3 and LaAlO 3 crystallized due to effect of grain size. LaCrO 3 film crystallized in the room temperature phase (orthorhombic). LaCoO 3 was highly oriented to (100) on MgO(100), and LaCrO 3 to (011) and (101) on sapphire(001). Lowest electric resistivities of LaCoO 3 and LaCrO 3 film on MgO were 9.8X10 -3 and 2.7X10 -1 Ω m, respectively, at room temperature.

  5. Steady state hemodynamic and energetic characterization of the Penn State/3M Health Care Total Artificial Heart.

    Science.gov (United States)

    Weiss, W J; Rosenberg, G; Snyder, A J; Pierce, W S; Pae, W E; Kuroda, H; Rawhouser, M A; Felder, G; Reibson, J D; Cleary, T J; Ford, S K; Marlotte, J A; Nazarian, R A; Hicks, D L

    1999-01-01

    Total Artificial Heart (TAH) development at Penn State University and 3M Health Care has progressed from design improvements and manufacturing documentation to in vitro and in vivo testing to characterize the system's hemodynamic response and energetic performance. The TAH system is completely implantable and intended for use as an alternative to transplantation. It includes a dual pusher plate pump and rollerscrew actuator, welded electronics and battery assembly, transcutaneous energy transmission system, telemetry, and a compliance chamber. In vitro testing was conducted on a Penn State mock circulatory loop with glycerol/water solution at body temperature. Tests were performed to characterize the preload and afterload response, left atrial pressure control, and power consumption. A sensitive preload response was demonstrated with left atrial pressure safely maintained at less than 15 mm Hg for flow rates up to 7.5 L/min. Variations in aortic pressure and pulmonary vascular resistance were found to have minimal effects on the preload sensitivity and left atrial pressure control. In vivo testing of the completely implanted system in its final configuration was carried out in two acute studies using implanted temperature sensors mounted on the electronics, motor, and energy transmission coil in contact with adjacent tissue. The mean temperature at the device-tissue interface was less than 4 degrees C above core temperature.

  6. Detailed DFT studies of the electronic structure and optical properties of KBaMSe{sub 3} (M = As, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Azam, Sikander; Khan, Saleem Ayaz; Khan, Wilayat [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Muhammad, Saleh; Udin, Haleem [Materials Modeling Lab, Department of Physics, Hazara University, Mansehra (Pakistan); Murtaza, G., E-mail: murtaza@icp.edu.pk [Materials Modeling Laboratory, Department of Physics, Islamia College University, Peshawar (Pakistan); Khenata, R., E-mail: khenata_rabah@yahoo.fr [Laboratoire de Physique Quantique et de Modélisation Mathématique (LPQ3M), Département de Technologie, Université de Mascara, Mascara 29000 (Algeria); Shah, Fahad Ali [Materials Modeling Lab, Department of Physics, Hazara University, Mansehra (Pakistan); Minar, Jan [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Ahmed, W.K. [ERU, College of Engineering, United Arab Emirates University, Al Ain (United Arab Emirates)

    2015-09-25

    Highlights: • The compounds are studied by FP-LAPW method within LDA, GGA, EV-GGA approximations. • All the compounds show indirect band gap nature. • Bonding nature is mixed covalent and ionic. • High absorption peaks and reflectivity ensures there utility in optoelectronic devices. - Abstract: Bonding nature as well as the electronic band structure, electronic charge density and optical properties of KBaMSe{sub 3} (M = As, Sb) compounds have been calculated using a full-potential augmented plane wave (FP-LAPW) method within the density functional theory. The exchange–correlation potential was handled with LDA and PBE-GGA approximations. Moreover, the Engel–Vosko generalized gradient approximation (EV-GGA) and the modified Beck–Johnson potential (mBJ) were also applied to improve the electronic band structure calculations. The study of band structure shows that KBaAsSe{sub 3}/KBaSbSe{sub 3} compounds have an indirect band gap of 2.08/2.10 eV which are in close agreement with the experimental data. The bonding nature has been studied as well using the electronic charge density (ECD) contour in the (1 0 1) crystallographic plane. It has been revealed that As/Sb–O atoms forms a strong covalent, while Ba–Se atoms form weak covalent bonding and the ionic bonding is mainly found between K and Ba atoms. Moreover, the complex dielectric function, absorption coefficient, refractive index, energy-loss spectrum and reflectivity have been estimated. From the reflectivity spectra, we found that KBaAsSe{sub 3} compound shows greater reflectivity than KBaSbSe{sub 3}, which means that KBaAsSe{sub 3} compound can be used as shielding material in visible and also in ultra violet region.

  7. Repair of Mybpc3 mRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy.

    Science.gov (United States)

    Mearini, Giulia; Stimpel, Doreen; Krämer, Elisabeth; Geertz, Birgit; Braren, Ingke; Gedicke-Hornung, Christina; Précigout, Guillaume; Müller, Oliver J; Katus, Hugo A; Eschenhagen, Thomas; Voit, Thomas; Garcia, Luis; Lorain, Stéphanie; Carrier, Lucie

    2013-07-02

    RNA trans-splicing has been explored as a therapeutic option for a variety of genetic diseases, but not for cardiac genetic disease. Hypertrophic cardiomyopathy (HCM) is an autosomal-dominant disease, characterized by left ventricular hypertrophy (LVH) and diastolic dysfunction. MYBPC3, encoding cardiac myosin-binding protein C (cMyBP-C) is frequently mutated. We evaluated the 5'-trans-splicing strategy in a mouse model of HCM carrying a Mybpc3 mutation. 5'-trans-splicing was induced between two independently transcribed molecules, the mutant endogenous Mypbc3 pre-mRNA and an engineered pre-trans-splicing molecule (PTM) carrying a FLAG-tagged wild-type (WT) Mybpc3 cDNA sequence. PTMs were packaged into adeno-associated virus (AAV) for transduction of cultured cardiac myocytes and the heart in vivo. Full-length repaired Mybpc3 mRNA represented up to 66% of total Mybpc3 transcripts in cardiac myocytes and 0.14% in the heart. Repaired cMyBP-C protein was detected by immunoprecipitation in cells and in vivo and exhibited correct incorporation into the sarcomere in cardiac myocytes. This study provides (i) the first evidence of successful 5'-trans-splicing in vivo and (ii) proof-of-concept of mRNA repair in the most prevalent cardiac genetic disease. Since current therapeutic options for HCM only alleviate symptoms, these findings open new horizons for causal therapy of the severe forms of the disease.Molecular Therapy-Nucleic Acids (2013) 2, e102; doi:10.1038/mtna.2013.31; published online 2 July 2013.

  8. Repair of Mybpc3 mRNA by 5′-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy

    Science.gov (United States)

    Mearini, Giulia; Stimpel, Doreen; Krämer, Elisabeth; Geertz, Birgit; Braren, Ingke; Gedicke-Hornung, Christina; Précigout, Guillaume; Müller, Oliver J; Katus, Hugo A; Eschenhagen, Thomas; Voit, Thomas; Garcia, Luis; Lorain, Stéphanie; Carrier, Lucie

    2013-01-01

    RNA trans-splicing has been explored as a therapeutic option for a variety of genetic diseases, but not for cardiac genetic disease. Hypertrophic cardiomyopathy (HCM) is an autosomal-dominant disease, characterized by left ventricular hypertrophy (LVH) and diastolic dysfunction. MYBPC3, encoding cardiac myosin-binding protein C (cMyBP-C) is frequently mutated. We evaluated the 5′-trans-splicing strategy in a mouse model of HCM carrying a Mybpc3 mutation. 5′-trans-splicing was induced between two independently transcribed molecules, the mutant endogenous Mypbc3 pre-mRNA and an engineered pre-trans-splicing molecule (PTM) carrying a FLAG-tagged wild-type (WT) Mybpc3 cDNA sequence. PTMs were packaged into adeno-associated virus (AAV) for transduction of cultured cardiac myocytes and the heart in vivo. Full-length repaired Mybpc3 mRNA represented up to 66% of total Mybpc3 transcripts in cardiac myocytes and 0.14% in the heart. Repaired cMyBP-C protein was detected by immunoprecipitation in cells and in vivo and exhibited correct incorporation into the sarcomere in cardiac myocytes. This study provides (i) the first evidence of successful 5′-trans-splicing in vivo and (ii) proof-of-concept of mRNA repair in the most prevalent cardiac genetic disease. Since current therapeutic options for HCM only alleviate symptoms, these findings open new horizons for causal therapy of the severe forms of the disease. PMID:23820890

  9. Electronic structure and magnetic properties of PbMO3 (M = Fe, Co, Ni) magnetic perovskites: An ab initio study

    Science.gov (United States)

    Erkişi, Aytaç; Yıldırım, Erdem Kamil; Gökoğlu, Gökhan

    2014-08-01

    We present the electronic, magnetic and structural properties of the magnetic transition metal oxides PbMO3 (M = Fe, Co, Ni) in cubic perovskite structure. The calculations are based on the density functional theory (DFT) within plane-wave pseudopotential method and local spin density approximation (LSDA) of the exchange-correlation functional. On-site Coulomb interaction is also included in calculations (LSDA+U). The systems are considered in ferromagnetic (FM) and G-type antiferromagnetic (G-AFM) order. FM structures are energetically more favored than G-AFM and than non-magnetic states for all the systems studied. The spin-polarized electronic band structures show that all the structures have metallic property in FM order without Hubbard-U interaction (Ueff = 0). However, the inclusion of on-site Coulomb interaction (Ueff = 7 eV) opens a semiconducting gap for majority spin channel of PbFeO3 and of PbNiO3 resulting in a half-metallic character. PbCoO3 system remains as metallic with LSDA+U scheme. Bonding features of all structures are largely determined by the hybridizations between O-p and d-states of transition metal atoms. The partial magnetic moment of Fe atom in PbFeO3 is enhanced by inclusion of Hubbard-U interaction (2.55 μB ⇒ 3.78 μB). Total magnetic moments of half-metallic PbFeO3 and of PbNiO3 compounds are very close to integer values.

  10. Activity identification of chimeric anti-caspase-3 mRNA hammerhead ribozyme in vitro and in vivo

    Institute of Scientific and Technical Information of China (English)

    XU; Renhuan; (

    2001-01-01

    [1]Andrew, F., Gerard, E., A license to kill, Cell, 1996, 85: 781-784.[2]Thornberry, N. A., Lazebnik, Y., Caspases: Enemies within, Science, 1998, 281: 1312-1316.[3]Kijima, H., Ishida, H., Ohkawa, T. et al., Therapeutic application of ribozymes, Pharmacol. Ther., 1995, 68: 247-264.[4]Phylactou, L. A., Kilpatrick, M. W., Wood, M. J., Ribozymes as therapeutic tools for genetic disease, Hum. Mol. Genet., 1998, 7(10): 1649-1653.[5]Bettrand, E., Pictet, R ., Grange, T., Can heamerhead ribozymes be efficient tools inactivate gene function? Nucleic Acids Res., 1994, 22: 293-300.[6]Lieber, A., Strauss, M., Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library, Mol. Cell Biol., 1995, 15: 540-551.[7]Xu, R. H., Zhou, X. Q., Xie, Q. et al., Preparation and identification of hammerhead ribozyme in vitro against rat caspase-3 mRNA fragment, Chin. J. Hepatol., 2000,8: 361-363.[8]Liu, J., Jin, Y. X., Wang, D. B., A novel vector for abundant expression of antisense RNA, triplex-forming RNA and ribozyme in vivo, High Technology Letters, 2000, 6: 84-88.[9]Sambrook, J., Fritsch, E. F., Maniatis, T., Molecular Cloning: A Laboratory Manual, 2nd ed., New York: Cold Spring Harbor Laboratory Press, 1989.[10]Porter, A. G., J?nicke, R. U., Emerging roles of caspase-3 in apoptosis, Cell Death Differ, 1999, 6: 99-104.[11]Cryns, V., Yuan, J., Proteases to die for, Genes Dev., 1998, 12: 1551-1570.[12]Narendra, K. V., Anikumar, R. K., Fritz, E., Recent developments in the hammerhead ribozyme field, Nucleic Acids Research, 1998, 26: 5237-5242.

  11. Design report for an indirectly cooled 3-m diameter superconducting solenoid for the Fermilab Collider Detector Facility

    Energy Technology Data Exchange (ETDEWEB)

    Fast, R.; Grimson, J.; Kephart, R.

    1982-10-01

    The Fermilab Collider Detector Facility (CDF) is a large detector system designed to study anti pp collisions at very high center of mass energies. The central detector for the CDF shown employs a large axial magnetic field volume instrumented with a central tracking chamber composed of multiple layers of cylindrical drift chambers and a pair of intermediate tracking chambers. The purpose of this system is to determine the trajectories, sign of electric charge, and momenta of charged particles produced with polar angles between 10 and 170 degrees. The magnetic field volume required for tracking is approximately 3.5 m long an 3 m in diameter. To provide the desired ..delta..p/sub T/p/sub T/ less than or equal to 1.5% at 50 GeV/c using drift chambers with approx. 200..mu.. resolution the field inside this volume should be 1.5 T. The field should be as uniform as is practical to simplify both track finding and the reconstruction of particle trajectories with the drift chambers. Such a field can be produced by a cylindrical current sheet solenoid with a uniform current density of 1.2 x 10/sup 6/ A/m (1200 A/mm) surrounded by an iron return yoke. For practical coils and return yokes, both central electromagnetic and central hadronic calorimetry must be located outside the coil of the magnet. This geometry requires that the coil and the cryostat be thin both in physical thickness and in radiation and absorption lengths. This dual requirement of high linear current density and minimal coil thickness can only be satisfied using superconducting technology. In this report we describe the design for an indirectly cooled superconducting solenoid to meet the requirements of the Fermilab CDF. The components of the magnet system are discussed in the following chapters, with a summary of parameters listed in Appendix A.

  12. Manual de lecciones sobre objetos

    OpenAIRE

    2010-01-01

    Pautas para la enseñanza inicial con niños, apoyado con Objetos. Traducido por S. Bond (Profesor de la Universidad Nacional). Contiene: Desarrollo de la observación - Desarrollo de las ideas de forma - Ejercicios preliminares para enseñar a los niños a observar formas - Desarrollo de las ideas de dibujo -  de color - de número - de tamaño - de peso -  de sonido -  sobre el cuerpo humano - de lugar - morales

  13. Prototipo de RINA sobre Ethernet

    OpenAIRE

    Bergesio, Leonardo

    2013-01-01

    Este PFM se enmarca dentro del trabajo a realizar por el proyecto IRATI. IRATI es un proyecto STReP (Specific Targeted Research Project) financiado por la Unión Europea dentro del programa FP7 (Seventh Framework Programme for Research and Technological Development). El objetivo general de IRATI es conseguir una mayor compresión y exploración de RINA. El trabajo que se reportará en este PFM es (aproximadamente) la primera fase del diseño y desarrollo de un prototipo de RINA sobre Ethernet en e...

  14. Sobre el Kelsen de Ferrajoli

    OpenAIRE

    Ruiz Manero, Juan

    2015-01-01

    El objeto de este trabajo es el de dar cuenta de las críticas a Kelsen contenidas en el último libro, todavía inédito, de Luigi Ferrajoli, Diritto e lógica. Dieci aporie nell'opera di Hans Kelsen, y formular algunas críticas a las tesis sostenidas en él por el propio Ferrajoli. Entre las críticas que el autor considera que cabe dirigir a este respecto a Ferrajoli, las principales afectan al carácter exclusivamente interno de la mirada ferrajoliana sobre el derecho, al carácter siempre opinabl...

  15. Sobre el contenido del despertar

    OpenAIRE

    Badr, Marisa

    2013-01-01

    El presente trabajo tiene como propósito situar algunas referencias, sobre lo que Freud denomina “la perturbación” en los sueños. De este modo, intentaremos situar algunas consideraciones respecto a los sueños de angustia como principal antecedente del fracaso de la función del sueño y del principio del placer como principio rector del aparato anímico. Tomaremos como punto de partida los sueños de angustia, en “La interpretación de los sueños” de Sigmund Freud.

  16. Sobre el contenido del despertar

    OpenAIRE

    Badr, Marisa

    2013-01-01

    El presente trabajo tiene como propósito situar algunas referencias, sobre lo que Freud denomina “la perturbación” en los sueños. De este modo, intentaremos situar algunas consideraciones respecto a los sueños de angustia como principal antecedente del fracaso de la función del sueño y del principio del placer como principio rector del aparato anímico. Tomaremos como punto de partida los sueños de angustia, en “La interpretación de los sueños” de Sigmund Freud.

  17. Generalidades sobre las fibras artificiales

    OpenAIRE

    González Salcedo, Luis Octavio

    2012-01-01

    Las fibras han sido utilizadas como materia prima en la elaboración de otros productos, como telas, papel, artesanías, entre otros, y como material de refuerzo en diversas matrices cerámicas y metálicas, con el fin mejorar o ganar propiedades, en materiales compuestos denominados composites. Las fibras pueden ser clasificadas de acuerdo con su origen, en fibras naturales y fibras artificiales. Una amplia exploración sobre el uso de fibras vegetales ha sido realizada, sin embargo su uso ...

  18. Generalidades sobre las fibras artificiales

    OpenAIRE

    González Salcedo, Luis Octavio

    2012-01-01

    Las fibras han sido utilizadas como materia prima en la elaboración de otros productos, como telas, papel, artesanías, entre otros, y como material de refuerzo en diversas matrices cerámicas y metálicas, con el fin mejorar o ganar propiedades, en materiales compuestos denominados composites. Las fibras pueden ser clasificadas de acuerdo con su origen, en fibras naturales y fibras artificiales. Una amplia exploración sobre el uso de fibras vegetales ha sido realizada, sin embargo su uso ...

  19. Algunas conjeturas sobre fracciones egipcias

    OpenAIRE

    Mora, Lyda Constanza; Lima, Isaac

    2003-01-01

    A continuación se presentan algunas conjeturas sobre las fracciones, con base en el tratamiento que los Egipcios hacían en antigüedad. En la primera parte se hace una introducción a las fracciones unitarias, y la representación de fracciones con numerador dos por medio de la suma de fracciones unitarias distintas. En la segunda parte, se presentan algunas de las conjeturas halladas a partir de la determinación de regularidades presentes en adiciones entre fracciones cuya suma es una fracción ...

  20. Desarrollo de aplicaciones sobre SCTP

    OpenAIRE

    López Aragoneses, Jorge

    2009-01-01

    En el año 2000, el grupo SIGTRAN definió un nuevo protocolo de capa de transporte conocido como Stream Control Transmission Protocol (SCTP) pensado, inicialmente, para transportar señalización telefónica SS7 sobre IP. La intención fue proveer en IP algunas de las características de confiabilidad de SS7. Por su versatilidad, más tarde, se ha propuesto utilizarlo en otras áreas. Para tal fin, se ha realizado este proyecto fin de carrera, en el cual se estudiarán las características del protocol...

  1. Exome Sequencing Identifies CCDC8 Mutations in 3-M Syndrome, Suggesting that CCDC8 Contributes in a Pathway with CUL7 and OBSL1 to Control Human Growth

    OpenAIRE

    Hanson, Dan; Murray, Philip G.; O'Sullivan, James; Urquhart, Jill; Daly, Sarah; Bhaskar, Sanjeev S.; Biesecker, Leslie G.; Skae, Mars; Smith, Claire; Cole, Trevor; Kirk, Jeremy; Chandler, Kate; Kingston, Helen; Donnai, Dian; Clayton, Peter E.

    2011-01-01

    3-M syndrome, a primordial growth disorder, is associated with mutations in CUL7 and OBSL1. Exome sequencing now identifies mutations in CCDC8 as a cause of 3-M syndrome. CCDC8 is a widely expressed gene that is transcriptionally associated to CUL7 and OBSL1, and coimmunoprecipitation indicates a physical interaction between CCDC8 and OBSL1 but not CUL7. We propose that CUL7, OBSL1, and CCDC8 are members of a pathway controlling mammalian growth.

  2. Blanco sobre blanco sobre blanco: Oiticica / Malevich / Nietzsche

    Directory of Open Access Journals (Sweden)

    Sérgio Martins

    2014-09-01

    Full Text Available El blanco sobre blanco, de Malevich, es una presencia fuerte en los escritos de Hélio Oiticica durante los setenta. Este artículo investiga los diferentes momentos del enlace de Oiticica con Malevich y el papel de esa noción en su pensamiento, articulándola a la referencia igualmente importante de Oiticica a John Cage y a la filosofía de Nietzsche. Así, es posible percibir tanto la centralidad del escrito para Oiticica en esta década, como la singularidad del modo de enunciación en él contenido, que puede ser descrito como aquel de un escrito manifiesto.

  3. Recursos y enlaces sobre comunidades de aprendizaje

    OpenAIRE

    Ferrer Esteban, Gerard

    2005-01-01

    Obras y artículos sobre el proyecto Comunidades de Aprendizaje desarrollado en el Estado español. Tesis doctorales sobre comunidades de aprendizaje. Fundamentación teórica de las comunidades de aprendizaje. Sitios en Internet relacionados con las comunidades de aprendizaje y proyectos afines de desarrollo comunitario en contextos escolares.

  4. Recursos y enlaces sobre comunidades de aprendizaje

    OpenAIRE

    Ferrer Esteban, Gerard

    2005-01-01

    Obras y artículos sobre el proyecto Comunidades de Aprendizaje desarrollado en el Estado español. Tesis doctorales sobre comunidades de aprendizaje. Fundamentación teórica de las comunidades de aprendizaje. Sitios en Internet relacionados con las comunidades de aprendizaje y proyectos afines de desarrollo comunitario en contextos escolares.

  5. As monografias sobre plantas medicinais

    Directory of Open Access Journals (Sweden)

    Valdir F. Veiga Junior

    2008-09-01

    Full Text Available As monografias sobre plantas medicinais ou drogas vegetais contêm informações para atender não somente aos órgãos de regulamentação, mas também às empresas industriais farmacêuticas e farmácias, e mesmo ao público consumidor. Este artigo revê as monografias da Comissão E, do American Botanical Council, ESCOP, PDR e da Organização Mundial de Saúde em suas origens, objetivos e formatos. Duas publicações recentemente organizadas pela FIOCRUZ do Rio de Janeiro e as contribuições da Farmacopéia Brasileira também são avaliadas.

  6. Constitucional sobre la justicia ordinaria

    Directory of Open Access Journals (Sweden)

    José Luis Cea Egaña

    2005-01-01

    Full Text Available El artículo analiza el efecto vinculante y de irradiación de las sentencias del Tribunal Constitucional sobre el conjunto del ordenamiento jurídico y de sus órganos. El autor toma partido por la consideración de la ratio decidendi del fallo como vinculante junto al dictum de la sentencia respectiva. Se plantea la necesidad que la LOC del Tribunal Constitucional explicite los efectos vinculantes de los fallos respecto de los tribunales ordinarios y especiales. Finalmente analiza los efectos de la res iudicata en el ámbito del control reparador de constitucionalidad de preceptos legales en control concreto y en control abstracto.

  7. Escenarios sobre el orden internacional

    Directory of Open Access Journals (Sweden)

    Luis Dallanegra Pedraza

    2012-01-01

    Full Text Available Luego de las grandes cambios que se dieron con la caída del Muro de Berlín y la desintegración en la URSS, se analizan, desde una perspectiva realista-sistémicaestructural, los componentes que intervienen en la generación del orden mundial, qué factores intervienen y cuáles son las diferentes aspiraciones respecto de las características que debería tener. Se tiene en especial consideración la creciente heterogeneización del sistema y la manera en que actores transnacionales operan como motores del futuro orden, predominando por sobre las posibilidades del actor históricamente dominante: el Estado-Nación. Se estudian las características principales del funcionamiento del sistema internacional y el significado de su marco institucional.

  8. Historicismo: notas sobre um paradigma

    Directory of Open Access Journals (Sweden)

    José D’Assunção Barros

    2012-08-01

    Full Text Available Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder, combinando-se com a consolidação dos modernos estados-nações. A especificação das características deste paradigma constituem o principal ponto de análise

  9. Puente sobre el rio Lay

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1959-11-01

    Full Text Available El puente sobre el río Lay, salva el río formando un ángulo de 69° con la dirección de éste. Situado en el término municipal de la Reorthe (Francia, sus características principales se concentran en sus tres vigas pretensadas, de 30 m de longitud, prefabricadas, siguiendo los procedimientos Preyssinet, proyectadas por la Société Technique pour l'Utilisation de la Précontrainte, que también se encargó de la redacción del proyecto general de ejecución, cuya realización se encomendó a la empresa constructora Dodin, y de los métodos empleados para la colocación de las vigas en obra.

  10. Reflexiones sobre una historia transicional

    Directory of Open Access Journals (Sweden)

    Carmen de la GUARDIA

    2010-02-01

    Full Text Available RESUMEN: Frente a la exclusiva y excluyente práctica historiográfica como práctica nacional e incluso nacionalista, surge recientemente la posibilidad de una historia transnacional que, sin renunciar a ciertas "maneras" clásicas de historiar, permita una reflexión menos "casticista" y de más altos vuelos. En este artículo y tras abordar la íntima relación entre la historiografía y el proceso de construcción de las naciones por un lado, y los últimos debates sobre el papel y el contenido de la historia en los sistemas educativos por otro, se profundiza sobre la naturaleza, el carácter, la metodología y los contenidos de una historia transnacional. Palabras Clave: Historiografía, nacionalismo, Historia nacional, Historia nacionalista, Historia transnacional. ABSTRACT: As opposed to the exclusive and excluding type of historiography as a national and even nationalistic practice, the possibility of a transnational type of history has recently arisen. Without renouncing certain classical "manners" of historiography, it allows for less purist and more far-reaching reflection. In this article, after tackling the intímate relationship between historiography and the process of nation building on the one hand, and the latest debates on the role and content of history in educational systems, on the other hand, an in-depth study is made of the nature, character, methodology and contents of transnational history. Key words: Historiography, Nationalism, National History, Nationalist History, Transnational History.

  11. Impuesto sobre el Valor Añadido. Apuntes

    OpenAIRE

    2013-01-01

    Apuntes sobre las siguientes cuestiones relacionadas con el Impuesto sobre el Valor Añadido: deducciones; exportaciones e importaciones; operaciones intracomunitarias; prorrata y sectores diferenciados.

  12. Puente sobre el rio Medway

    Directory of Open Access Journals (Sweden)

    Freeman, Fox, Ingenieros

    1963-02-01

    have been prestressed both longitudinally and transversally. Between the two circulation roadways an elastic barrier has been placed, supported on metal posts.El puente sobre el río Medway tiene la misión de salvar dicho río en el nuevo trazado de carretera necesario para aliviar el denso tráfico estival entre Dower y Londres. Está situado en las proximidades de la ciudad de Rochester. La estructura se ha construido utilizando las vías de concurso. De todos los tipos presentados se eligió una estructura de hormigón armado. La longitud total de la obra es de 1.000 m. Los tres tramos principales de la obra salvan el río. El central es de 152 m de luz, y los dos adyacentes son de 103 m cada uno. Los accesos tienen un total de 18 tramos, que arrojan una longitud de 654 m. La anchura del puente es de 34 m, y la calzada se ha subdividido en dos direcciones de tráfico de 7,30 m cada una y, además, se han dejado dos espaldones laterales de 2,40 m de anchura. En planta se puede admitir que el puente tiene una alineación recta con una ligerísima curva, y que en el plano vertical presenta una pendiente de desagüe entre las pilas 9 y 10. Los estribos son de hormigón armado: tipo celular el del este y de hormigón en masa el del oeste. Los estribos se apoyan sobre pilotes hexagonales de hormigón armado cuya circunferencia circunscrita tiene 55 cm de radio y de 12 a 20 m de longitud. Cuando el firme se hallaba a profundidades inferiores a 6 m, los estribos se cimentaban directamente sobre el firme. Las pilas constituyen pórtico y tienen una altura variable de 9 a 30 m sobre el nivel del suelo. Los tramos de acceso forman una estructura continua simplemente apoyada. Cada tramo se compone de ocho vigas longitudinales de 30 a 41 m de longitud y de 190 toneladas cada una. Estas vigas son del tipo pretensado y prefabricado. El tramo central es del tipo cantilever, constituido por dos brazos, de 30 m de longitud, formados por vigas cajón. Cada una de estas vigas consta

  13. Human Epidermal Growth Factor Receptor-3 mRNA Expression as a Prognostic Marker for Invasive Duct Carcinoma not Otherwise Specified

    Science.gov (United States)

    Hammoda, Ghada Ezat; El-Hefnawy, Sally Mohammed; Abdallah, Rania Abdallah

    2017-01-01

    Introduction Breast cancer is the most common cancer in women and the Erythroblastosis Oncogene B(ErbB) receptor family holds crucial role in its pathogenesis. Human Epidermal Growth Factor Receptor 3 (HER-3) gene over expression in breast tissue has been associated with aggressive clinical behaviour and bad prognosis. Aim To evaluate HER-3 mRNA expression level as a prognostic marker for breast cancer and to correlate its level with other established prognostic parameters. Materials and Methods This study was carried out on specimens of 100 cases that were divided into 40 patients presented with fibroadenoma and 60 patients presented with Invasive Ductal Carcinoma (IDC) not otherwise specified and underwent modified radical mastectomy. All specimens were investigated for HER-2/neu, ER and PR expression by Immunohistochemistry (IHC) and quantitative assay of HER-3 mRNA expression using real time PCR technique. Results There was a significant high HER3 mRNA level in carcinoma cases compared to fibroadenoma. In malignant cases, HER3 mRNA level was significantly associated with advanced T stage, advanced N stage, number of positive lymph nodes, large tumour size and cases associated with an adjacent in situ component. Moreover, HER-3 mRNA level was of highest values in Her-2/neu positive group followed by triple negative cases with the lowest level in luminal group (p<0.05). Conclusion HER-3 gene is upregulated in IDC especially those carrying poor prognostic features. HER-3 mRNA level may identify a subset of patients with a poor prognosis, and who could undergo further evaluation for the efficacy of HER3 targeted anticancer therapy. PMID:28384967

  14. Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3.

    Science.gov (United States)

    Dechavanne, Célia; Guillonneau, François; Chiappetta, Giovanni; Sago, Laïla; Lévy, Prisca; Salnot, Virginie; Guitard, Evelyne; Ehrenmann, François; Broussard, Cédric; Chafey, Philippe; Le Port, Agnès; Vinh, Joëlle; Mayeux, Patrick; Dugoujon, Jean-Michel; Lefranc, Marie-Paule; Migot-Nabias, Florence

    2012-01-01

    Mass spectrometry (MS) analysis for detection of immunoglobulins (IG) of the human IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. IgG3 is the most polymorphic human IgG subclass with thirteen G3m allotypes located on the constant CH2 and CH3 domains of the gamma3 chain, the combination of which leads to six major G3m alleles. Amino acid changes resulting of extensive sequencing previously led to the definition of 19 IGHG3 alleles that have been correlated to the G3m alleles. As a proof of concept, MS proteotypic peptides were defined which encompass discriminatory amino acids for the identification of the G3m and IGHG3 alleles. Plasma samples originating from ten individuals either homozygous or heterozygous for different G3m alleles, and including one mother and her baby (drawn sequentially from birth to 9 months of age), were analyzed. Total IgG3 were purified using affinity chromatography and then digested by a combination of AspN and trypsin proteases, and peptides of interest were detected by mass spectrometry. The sensitivity of the method was assessed by mixing variable amounts of two plasma samples bearing distinct G3m allotypes. A label-free approach using the high-performance liquid chromatography (HPLC) retention time of peptides and their MS mass analyzer peak intensity gave semi-quantitative information. Quantification was realized by selected reaction monitoring (SRM) using synthetic peptides as internal standards. The possibility offered by this new methodology to detect and quantify neo-synthesized IgG in newborns will improve knowledge on the first acquisition of antibodies in infants and constitutes a promising diagnostic tool for vertically-transmitted diseases.

  15. Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3.

    Directory of Open Access Journals (Sweden)

    Célia Dechavanne

    Full Text Available Mass spectrometry (MS analysis for detection of immunoglobulins (IG of the human IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. IgG3 is the most polymorphic human IgG subclass with thirteen G3m allotypes located on the constant CH2 and CH3 domains of the gamma3 chain, the combination of which leads to six major G3m alleles. Amino acid changes resulting of extensive sequencing previously led to the definition of 19 IGHG3 alleles that have been correlated to the G3m alleles. As a proof of concept, MS proteotypic peptides were defined which encompass discriminatory amino acids for the identification of the G3m and IGHG3 alleles. Plasma samples originating from ten individuals either homozygous or heterozygous for different G3m alleles, and including one mother and her baby (drawn sequentially from birth to 9 months of age, were analyzed. Total IgG3 were purified using affinity chromatography and then digested by a combination of AspN and trypsin proteases, and peptides of interest were detected by mass spectrometry. The sensitivity of the method was assessed by mixing variable amounts of two plasma samples bearing distinct G3m allotypes. A label-free approach using the high-performance liquid chromatography (HPLC retention time of peptides and their MS mass analyzer peak intensity gave semi-quantitative information. Quantification was realized by selected reaction monitoring (SRM using synthetic peptides as internal standards. The possibility offered by this new methodology to detect and quantify neo-synthesized IgG in newborns will improve knowledge on the first acquisition of antibodies in infants and constitutes a promising diagnostic tool for vertically-transmitted diseases.

  16. Puente sobre el Oosterschelde, Holanda

    Directory of Open Access Journals (Sweden)

    Hoving, H. T.

    1967-03-01

    Full Text Available This new bridge, forming part of the Delta project, is made of concrete, and was built by successive overhangs. Precast units were mainly used. The bridge is 5,000 m long, and is 11.85 m wide. The main spans are 95 m in length, except one, which can be opened up to sea traffic, which is 40 m long. The free height of the bridge over the sea is 15 m, which is insufficient for large ships. This required that one of the spans, in deep water, should open up, on hinges, and provide free passage to large ships. The intermediate bridge supports are of special interest. They rest on piles which go down to 38 m. They are hollow, cylindrical, of 4.35 m external diameter, and are driven into the ground in several stages, as they penetrate through the sands at the bottom of the Oosterschelde. To drive them in, an excavating device, inside the pile, was utilised, and also a dredging and suction mechanism, to clean out the bottom, and allow the piles to sink by gravity. But when external friction did not allow this to happen, the piles were weighed down with up to 500 tons of ballast. A series of three of these piles, in a row, makes up each bridge support. A cross member over the pile heads supports, in turn, the bridge deck. The bridge was built in successive sections, overhanging from each support, and then finally connected with a central portion. Use of precast units has been very extensive, so that the bridge can be justiaflably regarded as being prefabricated.Este nuevo puente, que forma parte del Plan de obras denominadas del Delta, es de hormigón y se ha construido por el procedimiento de voladizos sucesivos, utilizando, en su mayor parte, elementos prefabricados. Tiene una longitud total de 5.000 m; una anchura de 11,85 m; tramos principales de 95 m de luz, salvo uno, levadizo, que tiene 40 m. La altura libre sobre las ag^uas del mar es de 15 m, que es insuficiente para las naves de gran tonelaje; esto exigió que uno de sus tramos, en aguas

  17. Puente colgante sobre el Lillebaelt

    Directory of Open Access Journals (Sweden)

    Ostenfeld, Chr.

    1971-09-01

    Full Text Available This bridge, which was opened to traffic in October 1970 over the Lillebaelt, is the first of its kind in Denmark. It consists of a central span of 600 m, and two lateral ones of 240 m length each. The suspension cables, each 1,500 m, are the world's largest prefabricated cables. The bridge has original features, such as flaps on the main box girder, and new design of the anchorage blocks. These and other details are described in the article.Inaugurado en octubre de 1970, el puente colgante sobre el Lillebselt es el primer puente danés de este tipo. Consta de un tramo central de 600 m y dos tramos laterales de 240 m. Los cables sustentantes son, con sus 1.500 m de longitud, los mayores cables prefabricados del mundo. El puente presenta características origínales —empleo de «flaps» en la vigacajón de la superestructura, concepción nueva de los macizos de anclaje...— que, junto con el sistema de ejecución y las demás particularidades de la obra, son descritas en el artículo.

  18. Sobre a psicopatologia dos atos

    Directory of Open Access Journals (Sweden)

    Roberto Calazans

    2015-07-01

    Full Text Available Este artigo pretende apresentar a psicopatologia dos atos a partir do esquema de Jacques Lacan sobre a angústia. Diferenciamos os acting-out, a passagem ao ato, os sintomas, as inibições e a angústia fazendo uma duplicação do esquema de Lacan levando em consideração os registros do simbólico, do real e do imaginário. Esse esquema permite uma abordagem da questão dos atos do sujeito sem cair em uma perplexidade do clínico, nem na confusão entre os atos e a ação. Permite também uma melhor orientação do clínico em relação às diversas modalidades de respostas subjetivas que não se restringem à questão sintomática, que é o campo inaugural da clínica psicanalítica desde a sua fundação por Sigmund Freud. Acreditamos contribuir, assim, para um maior esclarecimento desse esquema no ensino de Lacan e para que ele possa servir de orientação para o tratamento dos atos do sujeito na clínica.

  19. Notas sobre publicaciones medievales portuguesas

    Directory of Open Access Journals (Sweden)

    José Luis MARTÍN

    2009-11-01

    Full Text Available Contra lo que debiera suceder, la proximidad con Portugal no incita al conocimiento de su historia y son muy raros los manuales de Historia de España en los que se concede a la Edad Media Portuguesa la importancia que realmente tiene, y en los tratados de Historia Medieval Europea el espacio dedicado a Portugal es mínimo, al menos hasta la época de los Descubrimientos; por otra parte, son contados los medievalistas españoles que se interesan por la historia de Portugal. Ante estos silencios y ante la escasa presencia en las bibliotecas españolas de obras portuguesas el estudiante de historia puede pensar que el país vecino carece de medievalistas de relieve, que su historia medieval está por hacer... y nada más lejos de la realidad como intentaré probar en este breve comentario, sin ánimo exhaustivo, sobre algunas de las últimas publicaciones aparecidas en Portugal.

  20. PERSPECTIVAS INFANTILES SOBRE LA TERRITORIALIDAD

    Directory of Open Access Journals (Sweden)

    Noelia Enriz

    2009-12-01

    Full Text Available En este trabajo nos proponemos un acercamiento a las diversas ideas infantiles sobre el territorio habitado, en el contexto particular de la población mbyá guaraní de Misiones. La fragilidad territorialidad a la que es expuesta la población indígena en Argentina se manifiestan cotidianamente en diversas áreas. La población mbyá, ha sido surcada por los límites de los estados nacionales de Paraguay, Brasil y Argentina. La sedentarización y los cercamientos de tierras en los diferentes estados, han impulsado transformaciones de las lógicas de subsistencia, de habitación y organización comunitaria. En el caso de la provincia de Misiones la acreditación burocrática de los títulos de tierras se encuentra aplazada, el estado no se compromete con la concreción de este derecho.

  1. Estudo multicasos sobre atividades inovativas

    Directory of Open Access Journals (Sweden)

    Sonia Regina Hierro Parolin

    2013-09-01

    Full Text Available Em estudos sobre competitividade argumenta-se que as empresas necessitam de estratégias baseadas em inovações e de capacidades internas em constantes e intensas transformações, não somente nos padrões tecnológicos, mas também no encadeamento do processo de gestão das atividades inovativas, como processos dinâmicos, não lineares e diversificados, em função de múltiplos fatores dos ambientes interno e externo. Para contribuir com essas discussões, neste artigo apresenta-se um estudo multicasos em quatro indústrias de médio e grande portes, de segmentos, densidades tecnológicas e históricos com inovações diferentes entre si. Como principais resultados, salientam-se o encadeamento das atividades inovativas como parte de uma estratégia organizacional para obter resultados com inovação e a afluência de todas as pessoas, e não somente as alocadas em pesquisa e desenvolvimento, para o cumprimento dessa estratégia.

  2. The Inhibitory Effects of an Antisense u-PAR Vector on Invasion of Highly Invasive Human Prostate Carcinoma PC-3M Cell Subclones

    Institute of Scientific and Technical Information of China (English)

    廖国宁; 李清芬; 冯友梅; 邓耀祖; 李卓娅; 龚非力; 马丁

    2003-01-01

    Summary: To observe the inhibitory effects of an antisense u-PAR vector on invasion of highly inva-sive PC-3M cell subclones, the effects of the antisense u-PAR on activity of MMP-9 in those highlyinvasive cell subclones were detected by a quantitative RT-PCR and zymography. The monolayer in-vasion assay and colony formation assay in soft agar were used. And tumorigenesis rate and invasionsby the cell subclones with or without the antisense u-PAR were observed in nude mice. It was foundthat in vitro growth of highly invasive PC-3M cell subclones transfected with the antisense u-PARwas declined, and the ability of anchorage-independent growth of those cell subclones was found de-creased sharply, with the inhibiting rate becoming 79 % and 60 %, respectively. Although the anti-sense u-PAR didn't change MMP-9 gene transcription, they could inhibit the activation of MMP-9 ofhighly invasive PC-3M cell subclones. Moreover, the tumorigenesis rate of the cell subclones with theantisense u-PAR decreased and the growth of a neoplasm also slowed down. Thet tests showed thedifference between experimental and control groups was statistically significant (P<0. 01). The anti-sense u-PAR vector could not only inhibit the invasion ability of highly invasive PC-3M cell subclonesin vitro but also restrain the growth of those cell subclones in vivo.

  3. 1.3 m m InGaAsN/ GaAs Lasers Grown by MOCVD Using TBAs and DMHy Sources

    Institute of Scientific and Technical Information of China (English)

    Gray Lin; C. M. Lu; C. H. Chiou; I. F. Chen; T. D. Lee; J. Y. Chi; D.A. Livshits

    2003-01-01

    We have demonstrated InGaAsN/ GaAs single quantum well (SQW) lasers grown by MOCVD using TBAs and DMHy sources. For un-buffer-strained InGaAsN/ GaAs system, our SQW lasers of 1.3 m m range is among the best in terms of transparency and threshold current density.

  4. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - PHYSICAL REMOVAL OF MICROBIOLOGICAL & PARTICULATE CONTAMINANTS IN DRINKING WATER: US FILTER 3M10C MICROFILTRATION MEMBRANE SYSTEM AT CHULA VISTA, CALIFORNIA

    Science.gov (United States)

    Verification testing of the US Filter 3M10C membrane system was conducted over a 44-day test period at the Aqua 2000 Research Center in Chula Vista, California. The test period extended from July 24, 2002 to September 5, 2002. The source water was a blend of Colorado River and ...

  5. Full solution, for crystal class 3m, of the Holland-EerNisse complex material-constant theory of lossy piezoelectrics for harmonic time dependence.

    Science.gov (United States)

    Piquette, Jean C; McLaughlin, Elizabeth A

    2007-06-01

    A complex material-constant theory of lossy piezoelectrics is fully solved for crystal class 3m for harmonic time dependence of the fields and stresses. A new demonstration that the theory's eigen coupling factor equation applies to the lossy alternating current (AC) case also is given. The solution presented for crystal class 3m provides a complete orthonormal set of eigenvectors and eigenvalues for the eigen coupling factor problem, and it also provides a complete orthonormal set of eigenvectors and eigenvalues for the eigen loss tangent problem, for this crystal class. It is shown that two positive coupling factors are sufficient to express an arbitrary 3m crystal state. Despite the complex nature of the material constants, the Holland-EerNisse theory produces fully real expressions for the coupling factors. The loss tangent eigenvalues also are fully real and positive. The loss eigenstates are important because driving a crystal in a loss eigenstate tends to minimize the impact of material losses. Given also is a set of loss inequalities for crystal class 3m. The loss inequalities of crystal class 6mm are recovered from these when d22 and s(E)14 both vanish.

  6. Influence of Functionalized Pyridine Ligands on the Radio/Chemical Behavior of [MI(CO)3]+ (M = Re and 99mTc) 2 + 1 Complexes

    Science.gov (United States)

    While a number of chelate strategies have been developed for the organometallic precursor fac-[M (OH2)3(CO)3]+ (M = Re, 99mTc), a unique challenge has been to improve the overall function and performance of these complexes for in vivo and in vitro applications. Since its synthesis, the fac-[M (CO)3]...

  7. Comentarios y reflexiones sobre las operaciones financieras

    OpenAIRE

    Pavón Bautista, María Mercedes

    1995-01-01

    En este trabajo se hacen comentarios y reflexiones sobre los tipos de operaciones financieras simples, operaciones financieras de constitución de capitales y operaciones financieras de amortización.

  8. Legislacion sobre seguridad vial en las Americas

    National Research Council Canada - National Science Library

    Hijar, Martha; Perez-Nunez, Ricardo; Inclan-Valadez, Cristina; Silveira-Rodrigues, Eugenia Maria

    2012-01-01

    La legislacion sobre cinco de los principales factores de riesgo de sufrir lesiones causadas por el transito, asi como el cumplimiento de la ley, son esenciales para forjar una cultura integral de seguridad vial...

  9. Los derechos de autor sobre obtenciones vegetales

    Directory of Open Access Journals (Sweden)

    Rosario Silva Gilli

    2015-01-01

    Full Text Available Contenido: Las creaciones en la agricultura. Los derechos de autor sobre obtenciones vegetales. El Convenio Internacional para la protección de las obtenciones vegetales (París 1961 y sus revisiones de Ginebra 1972, 1978,1991 Objeto de la protección legal. Condiciones del cultivar. Alcance de la protección. La protección de obtenciones vegetales en el Mercosur. Los Derechos de autor en el Mercosur. El Protocolo de Armonización de normas sobre Propiedad Intelectual en el Mercosur. El Acuerdo de Cooperación y facilitación sobre la protección de las obtenciones vegetales en los Estados Partes del Mercosur.  Alcance de la normativa Mercosur. Los Derechos sobre cultivares en Uruguay. Los Derechos de autor como derechos humanos. ¿Derechos de autor vs. derecho de propiedad intelectual? Reflexión final

  10. Reflexiones sobre pedagogías intensivas

    Directory of Open Access Journals (Sweden)

    Vizcaíno Pinilla Mercedes

    1996-06-01

    Full Text Available

    En el presente artículo se pretende recoger los conceptos filosóficos y los principios pedagógicos que orientan las pedagogías intensivas. Como valor primordial se encuentra la acción comunicativa como el eje sobre el cual se construyen las pedagogías intensivas orienta sobre las calidades que debe tener el maestro para desarrollarlas

  11. Efectos del recubrimiento de los cables sobre el comportamiento de las vigas pretensadas

    Directory of Open Access Journals (Sweden)

    Kaar, Paul H.

    1968-04-01

    Full Text Available This deals with an investigation of plastic sheathing applied to prestressing cables near the end of the beams, to prevent their direct bond with the concrete. Tests on five T beams, of 10.3 m length showed that the length of bonding required by section 2611 of the 1963 ACI Building Code is inadequate in the case of sheathed cables. The necessary length so that maximum bending moment and shear force can take place, when sheathing is adopted, is twice the anchorage length that the above specification requires.Se trata de un estudio sobre el revestimiento con tubos de plástico, usado para prevenir la adherencia entre el cable y el hormigón cerca de los extremos de las vigas pretensadas. Ensayos realizados sobre cinco vigas T de 10,3 m de longitud indicaron que la longitud de empotramiento que exige la sección 2611 de la 1963 ACI Building Code es inadecuada en el caso de cables revestidos. La longitud necesaria para que se desarrollen la flexión máxima y el esfuerzo cortante en las vigas, cuando se usa el revestimiento, es doble de la longitud del anclaje que señala dicha norma.

  12. PERSPECTIVAS INFANTILES SOBRE LA TERRITORIALIDAD

    Directory of Open Access Journals (Sweden)

    NOELIA ENRIZ

    2009-12-01

    Full Text Available In this paper we propose a different approach to children's ideas about the geographical area in the particular context of the Mbyá Guarani population, from Misiones (Argentine. The territorial fragility, that is exposed to the indigenous people in Argentina aremanifested daily in several areas. Mbyá population, has been crossed by the boundaries of national states of Paraguay, Brazil and Argentina. The sedentary and enclosures land processes in different states, have prompted changes in the logic of subsistence, housing and community organization. In Misiones province case, bureaucratic accreditation of land titles is postponed, the state is not committed to the realization of this right.RESUMEN: En este trabajo nos proponemos un acercamiento a las diversas ideas infantiles sobre el territorio habitado, en el contexto particular de la población mbyá guaraní de Misiones. La fragilidad territorialidad a la que es expuesta la población indígena en Argentina se manifiestan cotidianamente en diversas áreas. La población mbyá, ha sido surcada por los límites de los estados nacionales de Paraguay, Brasil y Argentina. La sedentarización y los cercamientos de tierras en los diferentes estados, han impulsado transformaciones de las lógicas de subsistencia, de habitación y organización comunitaria. En el caso de la provincia de Misiones la acreditación burocrática de los títulos de tierras se encuentra aplazada, el estado no se compromete con la concreción de este derecho.

  13. Consideraciones preliminares sobre la credibilidad

    Directory of Open Access Journals (Sweden)

    Fernando Verdugo

    2004-01-01

    Full Text Available A modo de introducción al Seminario Interno de Profesores de la Facultad de Teología de la PUC, el autor recuerda, en primer lugar, lo que suele entenderse por "credibilidad" y, también, algunos de los criterios generales por los cuales algo o alguien adquiere la calidad de creíble (el que sea razonable, relevante o significativo, capaz de producir gozo estético, etc.. Luego, en la parte más extensa, el autor vuelve a llamar la atención sobre la necesidad de atender a los condicionamientos culturales de la fe cristiana. La fe, al igual que toda experiencia humana, está culturalmente mediada. Tomar conciencia de ese hecho y asumir las consecuencias metodológicas es indispensable para una teología que quiere poner atención a los desafíos actuales y contribuir así a la credibilidad del cristianismoThis article reprints the introductory session to the internal seminar of lecturers from the Faculty of Theology of the UC. In the first place, the author sums up what is usually understood by `credibility' and the general criteria through which something or someone gains credibility (being reasonable, relevant or significant, capable of producing aesthetic pleasure. Then the author deals at length with the need to take notice of the cultural conditionings of the Christian faith. The faith, the same as any other human experience, is culturally mediated. It is crucial for theology to become aware of this fact and come to terms with its methodological consequences, if it wants to face current challenges and so contribute to the credibility of Christianity

  14. Sobre sujeitos racionais e apaixonados

    Directory of Open Access Journals (Sweden)

    Dílson Ferreira da Cruz

    2009-12-01

    Full Text Available

    Desde seu nascimento, a Retórica convive com um cisma insuperável: de um lado, Platão afirma que o orador deve buscar o bom e o verdadeiro; tem de seguir a lógica e sustentar-se com um discurso sóbrio, no qual prevalece a razão, o logos, e para o qual as coisas interessam pelo que são em si mesmas. No outro extremo da ágora está Cícero, para quem a Retórica não tem que procurar pela essência de nada, mas fazer com que a opinião do orador, seja ela verdadeira ou não, passe a ser também a do auditório. Para tanto, a lógica, tão acalentada por Platão, é de bem pouca valia, pois o orador, se quiser ter sucesso, deve levar os corações da cólera à doçura ou desta àquela. Como se vê, é uma retórica alicerçada sobre o pathos, ou, como diriam os semioticistas, no estado das almas. Este artigo se propõe a pensar essa questão utilizando o instrumental da semiótica dita tensiva com o objetivo de mostrar que, no discurso do grego, predominam as valências ligadas à extensidade, ao inteligível, às características dos objetos; ao passo que, nos ensinamentos do romano, são as valências relacionadas à intensidade, ao sensível, que se destacam.

  15. Nuevo puente de La Barca sobre el río Ter

    Directory of Open Access Journals (Sweden)

    Rodríguez-Borlado, Ramiro

    1967-12-01

    Full Text Available The new La Barca bridge, over the river Ter, is on the northern approach to Gerona, and carries the CN II road from Madrid to France, passing through Barcelona. It substitutes another bridge of the same name, which was inadequate for the heavy increase in traffic, during recent years. The bridge is 128 m long, consisting of two lateral spans, each 37 m long, and a central span of 54 m. The superstructure consists of ten hollow metal girders, of variable depth, arranged as three-part cantilevered structures. The lateral sections are cantilevered towards the centre, and the middle part of the span rests on their extremities. The girders support a reinforced concrete slab of 16 cm thickness and 14 m width: 8 m for the roadway, and 3 m for each of the sidewalks. The structure rests on two piles and two abutments of reinforced concrete, based on caisson foundations, except for one of the abutments, which is a reinforced concrete block. The project is completed by the approach roads and stonemasonry.El nuevo puente de La Barca, sobre el río Ter, está situado en el acceso norte a Gerona de la C. N. II de Madrid a Francia por Barcelona. Sustituye a otro del mismo nombre que resultaba insuficiente para la elevada intensidad de tráfico de esta vía. La luz del puente es de 128 m, dividida en dos tramos laterales, de 37 m de luz, y un tramo central, de 54 m. La superestructura está constituida por cinco vigas metálicas, huecas, de canto variable, dispuestas como vigas cantilever de tres elementos. Los elementos laterales se prolongan hacia el centro en voladizo, apoyándose sobre ellos el elemento central. Las vigas soportan una losa de hormigón armado de 16 cm de espesor, y 14 m de anchura: 8 m para la calzada y 3 m para cada uno de los andenes laterales. El conjunto se apoya sobre dos pilas y dos estribos, de hormigón armado, cimentados sobre cajones indios, excepto uno de los estribos, que está cimentado sobre macizo de hormigón armado

  16. Comparisons of fission track age-determination and radioactivation analysis among radiation fields. Characteristic values for pneumatic tube, JRR-3M PN2

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Tatsuro [Kagoshima Univ. (Japan). Faculty of Education; Tomura, Kenji

    1996-01-01

    It is necessary for Fission track age determination and radioactivation analysis to define the energy spectrum of a reactor neutron as the basis for calculating the nuclear reaction rate. This study was made aiming to define the spectrum for PN2 pneumatic tube of No. 3 plant of Japan Atomic Energy Research Institute (JAERI). Characteristics such as conventional flux, cross reaction, neutron temperature and integral fast flux were examined for 3 facilities; JRR-2, JRR-4 and JRR-3M. And the neutron spectrum for each facility was estimated based on the assumptions; Maxwell distribution for thermal neutrons, 1/E for intermediate neutrons and Watt`s formula for fast neutrons. The present results showed that the spectrum for JRR-3M, PN2 was discontinuous in the range from the intermediate to the fast neutron, whereas those for other facilities were found considerably improved. (M.N.)

  17. Consenso mexicano sobre la dispepsia

    Directory of Open Access Journals (Sweden)

    R. Carmona-Sánchez

    2017-10-01

    Full Text Available Desde la publicación de las guías de dispepsia 2007 de la Asociación Mexicana de Gastroenterología ha habido avances significativos en el conocimiento de esta enfermedad. Se realizó una revisión sistemática de la literatura en PubMed (01/2007 a 06/2016 con el fin de revisar y actualizar las guías 2007 y proporcionar nuevas recomendaciones basadas en evidencia. Se incluyeron todas las publicaciones en español e inglés, de alta calidad. Se redactaron enunciados que fueron votados utilizando el método Delphi. Se estableció la calidad de la evidencia y la fuerza de las recomendaciones según el sistema GRADE para cada enunciado. Treinta y un enunciados fueron redactados, votados y calificados. Se informan nuevos datos sobre definición, clasificación, epidemiología y fisiopatología. La endoscopia debe realizarse en dispepsia no investigada cuando hay datos de alarma o falla al tratamiento. Las biopsias gástricas y duodenales permiten confirmar infección por Helicobacter pylori y excluir enfermedad celiaca, respectivamente. Establecer una fuerte relación médico-paciente, cambios en la dieta y en el estilo de vida son útiles como medidas iniciales. Los bloqueadores H2, inhibidores de la bomba de protones, procinéticos y fármacos antidepresivos son efectivos. La erradicación de H. pylori puede ser eficaz en algunos pacientes. Con excepción de Iberogast y rikkunshito, las terapias complementarias y alternativas carecen de beneficio. No existe evidencia con respecto a la utilidad de prebióticos, probióticos o terapias psicológicas. Los nuevos enunciados proporcionan directrices basadas en la evidencia actualizada. Se presenta la discusión, el grado y la fuerza de la recomendación de cada uno de ellos.

  18. Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.

    Science.gov (United States)

    Bubier, Jason A; Jay, Jeremy J; Baker, Christopher L; Bergeson, Susan E; Ohno, Hiroshi; Metten, Pamela; Crabbe, John C; Chesler, Elissa J

    2014-08-01

    Extensive genetic and genomic studies of the relationship between alcohol drinking preference and withdrawal severity have been performed using animal models. Data from multiple such publications and public data resources have been incorporated in the GeneWeaver database with >60,000 gene sets including 285 alcohol withdrawal and preference-related gene sets. Among these are evidence for positional candidates regulating these behaviors in overlapping quantitative trait loci (QTL) mapped in distinct mouse populations. Combinatorial integration of functional genomics experimental results revealed a single QTL positional candidate gene in one of the loci common to both preference and withdrawal. Functional validation studies in Ap3m2 knockout mice confirmed these relationships. Genetic validation involves confirming the existence of segregating polymorphisms that could account for the phenotypic effect. By exploiting recent advances in mouse genotyping, sequence, epigenetics, and phylogeny resources, we confirmed that Ap3m2 resides in an appropriately segregating genomic region. We have demonstrated genetic and alcohol-induced regulation of Ap3m2 expression. Although sequence analysis revealed no polymorphisms in the Ap3m2-coding region that could account for all phenotypic differences, there are several upstream SNPs that could. We have identified one of these to be an H3K4me3 site that exhibits strain differences in methylation. Thus, by making cross-species functional genomics readily computable we identified a common QTL candidate for two related bio-behavioral processes via functional evidence and demonstrate sufficiency of the genetic locus as a source of variation underlying two traits.

  19. Specifika B2B marketingu na praktickém příkladu společnosti 3M

    OpenAIRE

    Javorská, Lucie

    2013-01-01

    The bachelor thesis focuses on the area of B2B marketing as a whole and on its main differences from marketing on consumer markets (B2C). Those differences are then concretely shown on the practical example of the company 3M Česko, specifically on the product category Office supplies, where the B2B marketing strategy, tactics as well as the operative activities are described.

  20. Motivace a spokojenost zaměstnanců společnosti 3M Česko, spol. s r.o.

    OpenAIRE

    Macečková, Lucie

    2009-01-01

    The goal of this diploma theses was to analyse working satisfaciton and motivation of 3M Česko employees. The first step was to collect the information about working motivation and satisfaction and afterwards the interpretation of the company research as well as the whole country research. Last thing was to bring the ideas about the ways how to increase the working motivation and satisfaction.

  1. Synthesis of Long Afterglow Phosphors MAl2O4:Eu2+, Dy3+(M=Ca, Sr, Ba) by Microemulsion Method and Their Luminescent Properties

    Institute of Scientific and Technical Information of China (English)

    Qiu Guanming; Chen Yongjie; Geng Xiujuan; Xiao Linjiu; Tian Yiguang; Sun Yanbin

    2005-01-01

    Long afterglow phosphors MAl2O4:Eu2+, Dy3+ (M=Ca, Sr, Ba) were synthesized by microemulsion method, and their crystal structure and luminescent properties were compared and investigated. XRD patterns of samples indicate that phosphors CaAl2O4:Eu2+, Dy3+ and SrAl2O4:Eu2+, Dy3+ are with monoclinic crystal structure and phosphor BaAl2O4:Eu2+, Dy3+ is with hexagonal crystal structure. The wide range of excitation spectrum of phosphors MAl2O4:Eu2+, Dy3+ (M=Ca,Sr,Ba) indicates that the luminescent materials can be excited by light from ultraviolet ray to visible light and the maximum emission wavelength of phosphors MAl2O4:Eu2+, Dy3+ (M=Ca, Sr, Ba) is found mainly at λem of 440 nm (M=Ca), 520 nm (M=Sr) and 496 nm (M=Ba) respectively, the corresponding colors of emission light are blue, green and cyna-green respectively. The afterglow decay tendency of phosphors can be summarized as three processes: initial rapid decay, intermediate transitional decay and very long slow decay. Afterglow decay curves coincide with formula I=At-n, and the sequence of afterglow intensity and time is Sr>Ca>Ba.

  2. Room temperature syntheses and thermal behaviors of hydrogarnets Sr{sub 3}M{sub 2}(OH){sub 12} (M = Al, Cr and Fe)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yun-Feng [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Yang, Zhi, E-mail: kmyangz@hotmail.com [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Li, Yong-Ming; Guo, Jing [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Fu, Wen-Fu, E-mail: fuwf@mail.ipc.ac.cn [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Wang, Ying-Xia; Liao, Fu-Hui [College of Chemistry and Molecular Engineering, Peking University, Beijing 100871 (China); Li, Jianye [University of Wisconsin-Madison, Madison, WI 53706 (United States)

    2015-07-15

    Highlights: • All starting materials were common metal inorganic salts. • Hydrogarnets were synthesized by solid state reaction at room temperature. • The novel synthesis method has an advantage of quick reaction and easy operation. • As-synthesized hydrogarnets have different morphologies. - Abstract: Hydrogarnets Sr{sub 3}M{sub 2}(OH){sub 12} (M = Al, Cr and Fe) were synthesized through a solid state reaction at room temperature with Al(NO{sub 3}){sub 3}·9H{sub 2}O, CrCl{sub 3}·6H{sub 2}O, FeCl{sub 3}·6H{sub 2}O, Sr(NO{sub 3}){sub 2} and NaOH as the starting materials. All X-ray diffraction (XRD) data of Sr{sub 3}M{sub 2}(OH){sub 12} were indexed by the cubic system with the space group of Ia{sup −}3d. XRD, differential thermal analysis and thermogravimetric (DTA–TG), and scanning electron microscopy (SEM) were employed to investigate the structural stability, thermal properties and morphologies of Sr based hydrogarnets. The cause of room temperature synthesis and the thermal decomposition behaviors of Sr-based hydrogarnets Sr{sub 3}M{sub 2}(OH){sub 12} (M = Al, Cr and Fe) are discussed.

  3. Comparison of Sarns 3M heparin bonded to Duraflo II and control circuits in a porcine model: macro- and microanalysis of thrombi accumulation in circuit arterial filters.

    Science.gov (United States)

    Larson, D F; Arzouman, D; Kleinert, L; Patula, V; Williams, S

    2000-01-01

    Heparin-bonded perfusion circuits have been reported to reduce the thrombus formation during various levels of systemic heparinization. The goal of this study was to compare the efficacy of thrombo-resistance of the Sarns 3M heparin-bonded circuit to Baxter Duraflo II and untreated control in a porcine model. Fifteen Yorkshire pigs (60-65 kg) were anesthetized, heparinized with 3000 IU, intravenously (i.v.) and surgically cannulated with an internal jugular outflow and a femoral vein inflow. All circuits consisted of a 22-Fr venous cannula, centrifugal pump, arterial filter, an 18-Fr cannula for return and connected with equal lengths of 3/8" polyvinyl chloride tubing. The flows were maintained at 2.0 l/min for 4 h. Thrombus formation in filter samples were morphometrically analyzed through macro-densitometry, light microscopy, and scanning electron microscopy (SEM). Our findings revealed that the 3M circuit had significantly less gross thrombus (p < 0.001), 66% and 84% less microscopic thrombi and fivefold less SEM-measured aggregates (p = 0.03) compared to the Duraflo II and uncoated groups. This study demonstrated that the 3M heparin-bonded circuit had significantly reduced the formation of micro- and macro-thrombi in the minimally heparinized pig model compared to the Duraflo II and untreated control circuits.

  4. Impacto psicosocial del Downsizing sobre los trabajadores

    Directory of Open Access Journals (Sweden)

    CRISTÓBAL JIMÉNEZ JIMÉNEZ

    2006-01-01

    Full Text Available El presente trabajo intenta ahondar en lo expuesto en un trabajo anterior sobre el downsizing como fenómeno psicosociolaboral, analizando su impacto psicosocial. En primer lugar, se exponen los diferentes niveles de comprensión de este fenómeno, para pasar al análisis de los efectos y consecuencias sobre las personas, diferenciando entre dos tipos de víctimas: a los que se van de la organización (despedidos y b los que se quedan en la organización (supervivientes, prestando especial atención a lo que se conoce ya como el "síndrome del superviviente", para lo que se aporta información sobre sus características, las variables moderadoras que intervienen y los modelos explicativos del mismo. Se termina con algunas consideraciones sobre la actualidad y relevancia de dicho síndrome sugiriendo la idea de que el fenómeno del downsizing y sus consecuencias sobre las personas nos enfrenta a lo que podríamos ya considerar como un nuevo síndrome de la Psicopatología Laboral: el síndrome del superviviente.

  5. DISERTACIÓN SOBRE JUSTICIA Y EQUIDAD

    Directory of Open Access Journals (Sweden)

    Sayuri P. Tamura M.

    2001-01-01

    Full Text Available «Disertación sobre equidad y justicia» es básicamente una respuesta a una inquietud en particular que yo tenía sobre las distintas posiciones que existen sobre estos dos temas y cómo definir cuál es la más acertada. Hice una descripción del punto de vista de Amartya Sen –la violación de los derechos sobre la propiedad privada es justificable si evitan las hambrunas2– frente al de Robert Nozick –la propiedad privada es un derecho fundamental y como tal debe ser respetado3–, sin embargo, aunque ambos enfoques son totalmente contrarios tienen mucho sentido, por lo cual es bastante difícil decidirse por uno en particular. Fue de esta forma, enfrentando sus opiniones, que yo logré desarrollar una posición frente a estas dos perspectivas, y así dar mi opinión al DISERTACIÓN SOBRE JUSTICIA Y EQUIDAD SAYURI P. TAMURA M. Estudiante de Economía y Negocios Internacionales de la Universidad ICESI. respecto. Al final, llegué a una conclusión, que aunque no es la más original y tampoco es la única, tiene mucho sentido y seguramente de ser posible, la situación del país podría cambiar para bien.

  6. K3M3 METAR

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — METAR is a routine scheduled observation and is the primary observation code used in the United States to satisfy requirements for reporting surface meteorological...

  7. Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic lupus erythematosus.

    Science.gov (United States)

    Xiang, Nan; Li, Xiang-Pei; Li, Xiao-Mei; Wang, Guo-Sheng; Tao, Jin-Hui; Pan, Hai-Feng; Fang, Xuan; Ma, Qian; Yu, Ning

    2014-11-01

    Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with complex genetic predisposing factors involved. Ets-1 transcription factor plays an important role in the suppressive activity of CD4(+)CD25(+) Treg cells and stable expression of FOXP3. To find its potential role in the pathogenesis of SLE, we investigate the mRNA expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25(+) Treg cells from patients with SLE. Real-time transcription-polymerase chain reaction analysis was used to determine the expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25(+) Treg cells from 36 patients with SLE and 18 sex-and-age-matched healthy controls. The Ets-1 mRNA expression level was decreased in patients with SLE [0.225 (0.135, 0.337)] than healthy controls [0.528 (0.303, 0.681)] (P Ets-1 and FOXP3 expression was also found in new-onset SLE subgroup when compared with healthy controls (P Ets-1 and FOXP3 mRNA was not significantly different in hyperactive and lower active SLE group when compared with inactive SLE group, respectively (P > 0.05). There were no significant differences between SLE with lupus nephritis (LN) and SLE without LN either (P > 0.05). Associations of Ets-1 and FOXP3 mRNA expression levels with major clinical and laboratory parameters of SLE patients were also analyzed. However, no significant association was found. Significant positive correlation was found between Ets-1 and FOXP3 mRNA expression in CD4(+)CD25(+) Treg cells from SLE patients (r = 0.698, P Ets-1 mRNA were decreased in SLE patients and Ets-1 expression was positively correlated with the expression of FOXP3. It indicated that Ets-1 may play an important role in the stable expression of FOXP3 in CD4(+)CD25(+) Treg cells.

  8. Expression of CYP2A3 mRNA and its regulation by 3-methylcholanthrene, pyrazole, and ß-ionone in rat tissues

    Directory of Open Access Journals (Sweden)

    A.B. Robottom-Ferreira

    2003-07-01

    Full Text Available Cytochrome P450 (CYP 2A enzymes are involved in the metabolism of numerous drugs and hormones and activate different carcinogens. Human CYP2A6, mouse CYP2A5 and rat CYP2A3 are orthologous enzymes that present high similarity in their amino acid sequence and share substrate specificities. However, different from the human and mouse enzyme, CYP2A3 is not expressed in the rat liver. There are limited data about expression of CYP2A3 in extrahepatic tissues and its regulation by typical CYP inducers. Therefore, the objective of the present study was to analyze CYP2A3 mRNA expression in different rat tissues by RT-PCR, and to study the influence of 3-methylcholanthrene, pyrazole and ß-ionone treatment on its expression. Male Wistar rats were divided into four groups of 5 rats each, and were treated ip for 4 days with 3-methylcholanthrene (25 mg/kg body weight, pyrazole (150 mg/kg body weight, ß-ionone (1 g/kg body weight, or vehicle. Total RNA was extracted from tissues and CYP2A3 mRNA levels were analyzed by semiquantitative RT-PCR. CYP2A3 mRNA was constitutively expressed in the esophagus, lung and nasal epithelium, but not along the intestine, liver, or kidney. CYP2A3 mRNA levels were increased in the esophagus by treatment with 3-methylcholanthrene and pyrazole (17- and 7-fold, respectively, in lung by pyrazole and ß-ionone (3- and 4-fold, respectively, although not statistically significant, in the distal part of the intestine and kidney by 3-methylcholanthrene and pyrazole, and in the proximal part of the intestine by pyrazole. CYP2A3 mRNA was not induced in nasal epithelium, liver or in the middle part of the intestine. These data show that, in the rat, CYP2A3 is constitutively expressed in several extrahepatic tissues and its regulation occurs through a complex mechanism that is essentially tissue specific.

  9. Length and amino acid sequence of peptides substituted for the 5-HT3A receptor M3M4 loop may affect channel expression and desensitization.

    Directory of Open Access Journals (Sweden)

    Nicole K McKinnon

    Full Text Available 5-HT3A receptors are pentameric neurotransmitter-gated ion channels in the Cys-loop receptor family. Each subunit contains an extracellular domain, four transmembrane segments (M1, M2, M3, M4 and a 115 residue intracellular loop between M3 and M4. In contrast, the M3M4 loop in prokaryotic homologues is <15 residues. To investigate the limits of M3M4 loop length and composition on channel function we replaced the 5-HT3A M3M4 loop with two to seven alanine residues (5-HT3A-A(n = 2-7. Mutants were expressed in Xenopus laevis oocytes and characterized using two electrode voltage clamp recording. All mutants were functional. The 5-HT EC(50's were at most 5-fold greater than wild-type (WT. The desensitization rate differed significantly among the mutants. Desensitization rates for 5-HT3A-A(2, 5-HT3A-A(4, 5-HT3A-A(6, and 5-HT3A-A(7 were similar to WT. In contrast, 5-HT3A-A(3 and 5-HT3A-A(5 had desensitization rates at least an order of magnitude faster than WT. The one Ala loop construct, 5-HT3A-A(1, entered a non-functional state from which it did not recover after the first 5-HT application. These results suggest that the large M3M4 loop of eukaryotic Cys-loop channels is not required for receptor assembly or function. However, loop length and amino acid composition can effect channel expression and desensitization. We infer that the cytoplasmic ends of the M3 and M4 segments may undergo conformational changes during channel gating and desensitization and/or the loop may influence the position and mobility of these segments as they undergo gating-induced conformational changes. Altering structure or conformational mobility of the cytoplasmic ends of M3 and M4 may be the basis by which phosphorylation or protein binding to the cytoplasmic loop alters channel function.

  10. Correlation of integrin β3 mRNA and vascular endothelial growth factor protein expression profiles with the clinicopathological features and prognosis of gastric carcinoma

    Institute of Scientific and Technical Information of China (English)

    Shu-Guang Li; Zai-Yuan Ye; Zhong-Sheng Zhao; Hou-Quan Tao; Yuan-Yu Wang; Chun-Yu Niu

    2008-01-01

    AIM: To investigate integrin 133 mRNA and vascular endothelial growth factor (VEGF) protein expression in gastric carcinoma, and its correlation with microvascular density, growth-pattern, invasion, metastasis and prognosis. METHODS: In situ hybridization(ISH) of integrin β3 mRNA and immunohistochemistry of VEGF and CD34 protein were performed on samples from 118 patients with gastric cancer. RESULTS: The positive rate of integrin 133 mRNA in non- tumor gastric mucosa (20%) was significantly lower than that of the gastric cancer tissue (52.5%, x2 = 10.20, P < 0.01). In patients of infiltrating type, stage T3-T4, vessel invasion, lymphatic metastasis, hepatic or peritoneal metastasis, the positive expression rates of integrin β3 mRNA were significantly higher than those in patients of expanding type (P < 0.01), stage T1-T2 (P < 0.01), non-vessel invasion (P < 0.01), without lymphatic metastasis (P < 0.01), without hepatic and peritoneal metastasis (P < 0.01), respectively. In patients of infiltrating type, stage T3-T4, vessel invasion, lymphatic metastasis, hepatic or peritoneal metastasis, the positive expression rates of VEGF protein were significantly higher than those in patients of expanding type (P < 0.01), stage T1-T2 (P < 0.01), non-vessel invasion (P < 0.01), without lymphatic metastasis (P < 0.01), without hepatic and peritoneal metastasis (P < 0.01), respectively. In patients of infiltrating type, stage T3-T4, vessel invasion, lymphatic metastasis, hepatic or peritoneal metastasis, the mean MVD were significantly higher than those in patients of expanding type (P < 0.01), stage T1-T2 (P < 0.01), non-vessel invasion (P < 0.01), without lymphatic metastasis (P < 0.01), without hepatic and peritoneal metastasis (P < 0.01), respectively. It was found that the positive expression rate of integrin β3 mRNA was positively related to that of VEGF protein (P < 0.01) and MVD (P < 0.05), meanwhile the positive expression rate of

  11. 前列腺液中DD3mRNA定量检测无侵入性诊断前列腺癌的意义%Significance of non-invasive diagnosis of prostate cancer by quantitative-detection of DD3mRNA in prostatic fluid

    Institute of Scientific and Technical Information of China (English)

    陈海文; 甘为民; 张楠; 王子明; 陈琦; 李洪亮

    2013-01-01

    目的 探讨前列腺按摩后前列腺液沉渣中DD3mRNA含量在前列腺癌诊断中的应用价值.方法 在前列腺穿刺活检前或术前麻醉后收集前列腺按摩后患者的前列腺液.其中前列腺癌(Pca)患者31例,前列腺增生患者(BPH)59例,离心取细胞沉淀物,用荧光实时定量逆转录-聚合酶链反应(Real time RT-PCR)方法检测DD3mRNA和PSAmRNA含量,以PSAmRNA作为管家基因校正前列腺液沉渣中的前列腺细胞,以DD3mRNA/PSAmRNA比值表示DD3mRNA含量.SPSS 13.0分析相关数据,以穿刺活检或术后病理检查结果为金标准,用受试者工作特征曲线(ROC)对DD3mRNA诊断性能进行分析,并与血清:PSA进行比较,同时探讨前列腺液DD3mRNA相对定量值阳性率与病理分级的关系.结果 前列腺癌患者前列腺液DD3mRNA表达量明显高于BPH,差异具有统计学意义(P<0.05).ROC曲线分析结果显示,曲线下面积(ROC-AUC) =0.879(95%CI=0.795~0.964).DD3 mRNA相对定量值截断值取0.015313时,其诊断效能最大.其灵敏度为0.806,特异度为0.864,准确性0.67,阳性预测值75.8%,阴性预测值89.5%,阳性似然比、阴性似然比分别为5.97、0.224.若血清tPSA分别以4ng/ml和10ng/ml为截断值时,灵敏度分别为83.8%和54.84%,特异度分别为61.02%和83.05%,不同病理分级之间DD3mRNA的阳性率差异无统计学意义(P>0.05).结论 前列腺液中DD3mRNA测定的诊断性能明显高于血清PSA,作为前列腺癌的一种非损伤性诊断方法具有良好的应用前景.%Objective To study the expressions of differential display code 3 mRNA (DD3 mRNA) in the prostatic fluid samples of patients with prostate cancer and its diagnostic value in prostate cancer. Methods The prostatic fluid samples were collected before biopsy or operation, including 31 benign prostatic hyperplasia and 59 prostate cancer patients; the total RNA had been extracted for Real time RT-Polymerase chain reaction; agarose gel electrophoresis

  12. DURKHEIM Y BOURDIEU: REFLEXIONES SOBRE EDUCACIÓN

    OpenAIRE

    Morales Zúñiga, Luis Carlos

    2013-01-01

    El artículo realiza una comparación sobre la noción de educación y su objetivo, en el pensamiento de Emile Durkheim y de Pierre Bourdieu. Primeramente se reflexiona sobre algunas consideraciones relativas a la influencia de la sociología de Durkheim sobre la obra sociológica de Bourdieu, enfatizando sobre todo el racionalismo y el estructuralismo de ambos autores. Posteriormente se elabora una reflexión sobre algunos puntos comunes, y a la vez sobre las distancias que existen entre ambos auto...

  13. Refletindo sobre a violência

    Directory of Open Access Journals (Sweden)

    Cynara Marques Hayeck

    2015-05-01

    Full Text Available O presente artigo trata a questão da violência como uma prática corrente desde a antigüidade, e faz um esboço sobre como o conceito desta é tratado por alguns autores, principalmente após o processo civilizatório do homem, além de ponderar sobre as relações estabelecidas entre violência, classe social e o mito da não-violência.

  14. Principios sobre semáforos

    OpenAIRE

    Valencia Alaix, Víctor Gabriel

    2000-01-01

    Debido a la ausencia de una publicación que reuniese los aspectos más relevantes sobre semáforos y en el marco académico sobre ingeniería de tránsito de los cursos de pregrado y posgrado en Vías y Transporte de la Universidad Nacional de Colombia - Sede Medellín, se ha preparado este documento como guía introductoria a dicho tema. En su preparación se han recogido los tópicos principales de varias publicaciones internacionales y nacionales, además, su desarrollo ha considerado la experi...

  15. Medidas cautelares sobre el responsable tributario

    OpenAIRE

    Martínez Muñoz, Yolanda

    2014-01-01

    Las medidas que con una finalidad cautelar pueden ser adoptadas sobre el responsable tributario deben adaptarse a lo dispuesto en el artículo 81 de la LGT, en relación con sus requisitos, clases, procedimiento y límites. No obstante, la adopción de medidas cautelares sobre una persona distinta del deudor principal presenta cierta particularidades que pueden resultar interesantes desde un punto de vista teórico y práctico, siendo dichas cuestiones las que constituyen el objeto del presente tra...

  16. Sobre la sublimación

    OpenAIRE

    2007-01-01

    Este documento presenta un trabajo de investigación realizado sobre un concepto clave para la producción teórica y la enseñanza en psicología, como es la noción de sublimación. La investigación indaga la sublimación en el marco de la teoría psicoanalítica, con el objeto de profundizar su explicación conceptual y decidir sobre la pertinencia de tomarlo como noción clave para explicar la producción social del saber.

  17. Debate sobre estudios postcoloniales y subalternos

    OpenAIRE

    David Morris; McLean, Ian S.; Hillel Eyal; Ivette Hernández; Richard W. Slata; Betsy Campisi; Jackson, Robert H; William Patterson; Kathryn Lehman; Chad Black; Michelle Molina; Ann Twinam; Dennis Hidalgo

    2001-01-01

    A partir de los comentarios a la reseña elaborada por Ian S. Mclean sobre el libro: Cuerpos incas y el cuerpo de Cristo. El Corpus Christi en Cuzco colonial, Perú, escrito por Carolyn Dean, surge un debate sobre los Estudios Postcoloniales y Subalternos, que se desarrolló entre el 12 de agosto y el 3 de septiembre de 2001, a través de la lista de correo electrónico de H-Latam, grupo de discusión dedicado a la historia latinoamericana. En él participaron destacados especial...

  18. Jose carlos mariategui: sus articulos sobre arte

    OpenAIRE

    Henríquez, Cecilia

    2014-01-01

    En la prolífica obra que colma la corta vida del pensador latinoamericano,se encuentran profundas reflexiones sobre el arte que valela pena recordar en e1 año del centenario de su nacimiento. Los juiciosque propone sobre el arte están n1ediados por su pensamiento marxista.Aunque gran conocedor del arte de sus contemporáneos, sucompromiso socialista, cada vez mayor, reduce el espacio del análisisestilístico.Un punto de partida para observar el pensamiento estético deJosé Carlos Mariátegui es s...

  19. Consideraciones sobre los ensayos de laboratorio

    Directory of Open Access Journals (Sweden)

    José Gabriel Gómez Cortés

    2013-12-01

    Full Text Available Texto de la conferencia dictada por el autor en el Instituto de la Construcción y del Cemento en Madrid. Eduardo Torroja, España, como asistente al IX Curso de Estudios Mayores de la Construcción sobre "LA EDIFICACION Y SU PATOLOGÍA". Se analizan aspectos sobre: los criterios para solicitar ensayos, muestreo, variabilidad de resultados y reproducibilidad de ensayos, criterios de aceptación e importancia de la retroalimentación.

  20. Impacto psicosocial del Downsizing sobre los trabajadores

    OpenAIRE

    CRISTÓBAL JIMÉNEZ JIMÉNEZ; JOSÉ LUIS SÁNCHEZ LAGUNA

    2006-01-01

    El presente trabajo intenta ahondar en lo expuesto en un trabajo anterior sobre el downsizing como fenómeno psicosociolaboral, analizando su impacto psicosocial. En primer lugar, se exponen los diferentes niveles de comprensión de este fenómeno, para pasar al análisis de los efectos y consecuencias sobre las personas, diferenciando entre dos tipos de víctimas: a) los que se van de la organización (despedidos) y b) los que se quedan en la organización (supervivientes), prestando especial atenc...

  1. Generalidades sobre el 68 en la narrativa

    OpenAIRE

    Ocampo, Aurora M.

    2013-01-01

    Es mucho lo que se ha escrito sobre el movimiento estudiantil de 1968, según mis registros, cerca de un centenar de libros, además de innumerables artículos, ensayos, narraciones, poemas, teatro y reseñas a los libros como a los grandes ensayos, aparecidos en publicaciones periódicas. Por otro lado, muchos de los libros, ya sean testimoniales, de reflexión sobre lo sucedido, antologías de poesías, ensayos, cuentos, teatro y narrativa en general se han reeditado varias veces; ahora, con motivo...

  2. 3M纸片法在水质检验工作中的应用%Applications 3M Method in Water Quality Testing Work

    Institute of Scientific and Technical Information of China (English)

    吴波

    2015-01-01

    Objective To investigate the value of 3M method in water quality testing work. Methods Comparison of two methods to take random samples of the area of tap water, the second pressurized water samples and a total of 54 well water samples and water quality testing plate count method were used to detect disk diffusion method 3M Petrifilm (3M paper method). the total number of bacterial strains and testing standards in water samples. Results There were detected the presence of E. coli and Staphylococcus aureus significant differences were statistically significant (P<0.05). 3M method to detect the use of tap water samples, the second pressurized water sample and the average number of colonies well water sample was (32.7±8.31), the average number of colonies in plate count assay was (22.9±2.58) months, the two groups 54 parts of water samples to detect the average number of colonies was statistically significant difference (P<0.05). Conclusion Accurate conclusions 3M method to detect water quality, specificity, convenient, has application value.%目的:探讨3M纸片法在水质检验工作中的应用价值。方法随机采取该辖区内末梢水样品、二次加压水样品和井水样品共54份,分别采用3M Petrifilm检测纸片法(3M纸片法)和平皿计数法进行水质检验,比较两种方法检测标准菌株和水样中的细菌总数。结果比较两组方法检测大肠杆菌和金黄色葡萄球菌的结果,差异有统计学意义(P<0.05)。采用3M纸片法检测末梢水样品、二次加压水样品和井水样品的平均菌落数为(32.7±8.31)个,平皿计数法检测的平均菌落数为(22.9±2.58)个,两组方法检测54份水样品平均菌落数比较,差异有统计学意义(P<0.05)。结论3M纸片法检测水质的准确度高、特异性强,方便快捷,具有推广应用价值。

  3. First-order ion-optics calculations for an Accelerator Mass Spectrometry system using SRIM and S{sup 3}M

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Guzman, J.M., E-mail: jm_gomez@us.es [Centro Nacional de Aceleradores (CNA), Avda. Thomas Alva Edison 7, Isla de la Cartuja, 41092 Seville (Spain); Dpto. de Fisica Atomica, Molecular y Nuclear, University of Seville (Spain); Gomez-Morilla, I. [Technische Universitaet Dresden, Fakultaet Maschinenwesen, Professur fuer Magnetofluiddynamik (Germany); Enamorado-Baez, S.M.; Moreno Suarez, A.I.; Pinto-Gomez, A.R. [Centro Nacional de Aceleradores (CNA), Avda. Thomas Alva Edison 7, Isla de la Cartuja, 41092 Seville (Spain)

    2012-06-15

    In this paper, we describe the transport of a simulated beam, created with the S{sup 3}M beam generation module, along the real beam line of the Accelerator Mass Spectrometry (AMS) facility located at Centro Nacional de Aceleradores (CNA, Seville, Spain). The beam transport through the optical system was determined using the transfer-matrix method, which can easily calculate the beam envelopes without having to track all individual particles, evaluating the ability of such systems and saving computation time. The beam size results given by S{sup 3}M were compared to the real beam size in three of the four image points that the system has (P1, P2 and P3), corresponding with the position of Faradays Cups where the {sup 127}I current was measured, obtaining a good agreement between them. This suggests that the first order approximation model is enough to simulate the optical behavior of the system. It is shown that the beam line has a focusing behavior, minimizing the beam size from {+-}3 mm at the exit of the ion source to {+-}1.09 mm at the detector's entrance window. Using the beam emittance diagram simulations, it is shown that when ions pass through the stripper, the angles of their trajectories are altered by scattering with the gas molecules and the geometrical emittance enlarges, according to Liouville's Theorem. The study presented in this work gives confidence and open new perspectives in simulations with S{sup 3}M in AMS facilities contributing to the understanding of their optical behavior.

  4. Design of a head phantom produced on a 3D rapid prototyping printer and comparison with a RANDO and 3M lucite head phantom in eye dosimetry applications.

    Science.gov (United States)

    Homolka, Peter; Figl, Michael; Wartak, Andreas; Glanzer, Mathias; Dünkelmeyer, Martina; Hojreh, Azadeh; Hummel, Johann

    2017-02-13

    An anthropomorphic head phantom including eye inserts allowing placement of TLDs 3 mm below the cornea has been produced on a 3D printer using a photo-cured acrylic resin to best allow tissue equivalence. Thus Hp(3) can be determined in radiological and interventional photon radiation fields. Eye doses and doses to the forehead have been compared to an Alderson RANDO head and a 3M Lucite skull phantom in terms of surface dose per incident air kerma for frontal irradiation since the commercial phantoms do not allow placement of TLDs 3 mm below the corneal surface. A comparison of dose reduction factors (DRFs) of a common lead glasses model has also been performed. Eye dose per incident air kerma were comparable between all three phantoms (printed phantom: 1.40, standard error (SE) 0.04; RANDO: 1.36, SE 0.03; 3M: 1.37, SE 0.03). Doses to the forehead were identical to eye surface doses for the printed phantom and the RANDO head (ratio 1.00 SE 0.04, and 0.99 SE 0.03, respectively). In the 3M Lucite skull phantom dose on the forehead was 15% lower than dose to the eyes attributable to phantom properties. DRF of a sport frame style leaded glasses model with 0.75 mm lead equivalence measured were 6.8 SE 0.5, 9.3 SE 0.4 and 10.5 SE 0.5 for the RANDO head, the printed phantom, and the 3M Lucite head phantom, respectively, for frontal irradiation. A comparison of doses measured in 3 mm depth and on the surface of the eyes in the printed phantom revealed no difference larger than standard errors from TLD dosimetry. 3D printing offers an interesting opportunity for phantom design with increasing potential as printers allowing combinations of tissue substitutes will become available. Variations between phantoms may provide a useful indication of uncertainty budgets when using phantom measurements to estimate individual personnel doses.

  5. Marketingová strategie společnosti 3M v sociálních médiích

    OpenAIRE

    Němec, Tomáš

    2016-01-01

    Diploma thesis focus on social media as a phenomenon of modern times and their use in a marketing. I will introduce four most frequently used social media - Facebook, Instagram, Twitter and YouTube as well as an outline the possibility of their use in marketing. Marketing strategy in social media I decided to introduce through a concrete example - an international company 3M. This company I chose mainly because it operates in the market of industrial products, where online marketing is not as...

  6. Las fuentes cristianas sobre Jesús

    Directory of Open Access Journals (Sweden)

    Melero Martínez, J.M.

    2010-01-01

    Full Text Available El artículo es una presentación de las fuentes históricas sobre Jesús de Nazaret: fuentes sinópticas, fuente Q, fuentes afines a la gnosis, fragmentos de evangelio con material sinóptico o joánico, evangelios judeocristianos y otras fuentes.

  7. Los derechos reales sobre cosa ajena

    OpenAIRE

    Panero Oria, Patricia

    2011-01-01

    Esta presentación cierra la serie de presentaciones que sa han realizado sobre los Derechos reales, según el Plan Docente seguido en la Facultad de Derecho de la Universidad de Barcelona, y que sirven de guía para el estudio de la materia.

  8. O pensamento de Marx sobre a subjetividade

    Directory of Open Access Journals (Sweden)

    Eduardo F. Chagas

    2013-08-01

    Full Text Available O pensamento de Karl Marx sobre a subjetividade humana é pouco conhecido e divulgado na língua portuguesa, e, no Brasil, particularmente, carece ainda de um estudo amplo, explícito e sistemático. Meu artigo pretende esboçar uma reflexão mais completa de sua filosofia sobre a subjetividade humana, insistindo não somente na crítica, mas também, e especialmente, na compreensão da referida questão, a partir de uma leitura imanente e estrutural de suas obras, no original. Vale ainda ressaltar que minha investigação se apoia na conexão entre subjetividade e objetividade, entre sujeito e objeto, inquirindo se há um determinismo da objetividade sobre a subjetividade, ou seja, se essas duas determinações são contraditórias no interior do pensamento marxiano, comprometendo, pois, as suas reflexões acerca da crítica à filosofia especulativa de Hegel e ao empirismo da economia clássica, ou se, na verdade, tal conexão é o segredo recôndito de sua filosofia sobre a subjetividade humana.

  9. Puente pretensado sobre el Guadarrama. Villalba

    Directory of Open Access Journals (Sweden)

    Páez, A.

    1958-12-01

    Full Text Available En este artículo se describe y comenta la solución dada al puente de hormigón pretensado sobre el río Guadarrama, primero de los construidos mediante dovelas prefabricadas y solidarizadas después, mediante el pretensado de la armadura longitudinal.

  10. Un nuevo libro sobre Juan de Castellanos

    Directory of Open Access Journals (Sweden)

    Alberto Miramón

    1979-02-01

    Full Text Available El Centro de Historia del Táchira ha auspiciado la publicación, por la Editorial Kelly de Bogotá, del segundo libro que monseñor Mario Germán Romero ha escrito sobre la vida y obra, tan apasionante ambas, de don Joan de Castellanos

  11. The expression of DcR3 mRNA in peripheral blood mononuclear cells from patients with Guillain-Barré syndrome%吉兰-巴雷综合征外周血单个核细胞DcR3mRNA表达

    Institute of Scientific and Technical Information of China (English)

    陆嘉茵; 李静; 朱太卿; 田发发; 杨欢; 陈毓茜

    2011-01-01

    Objective To investigate the expression of DcR3 mRNA in peripheral blood mononuclear cells (PBMCs) from patients with Guillain-Barré syndrome (GBS).And to discuss the correlation among cerebrospinal fluid (CSF) -Ig, the severity of GBS and DcR3 mRNA.Methods Thirty-six patients with GBS and 20 healthy controls were included.The expression of DcR3 mRNA in PBMCs was detected by reverse transcription-polymerase chain reaction (RT-PCR).The correlation between the severity of GBS and the expression of DcR3 mRNA was analyzed.The CSF level of CSF-Ig was also analyzed.Results DcR3 mRNA level in GBS patients (0.40 ± 0.08) was significantly higher than in the healthy control (0.17 ± 0.04) (P<0.01).The expression of DcR3 mRNA was comparable between the mild group (0.39 ±0.07) and the severe group (0.41±0.05) (P>0.05).The level of CSF-Ig was also comparable between the mild group [IgG (0.l23 ±0.113) g/L, IgA (0.016± 0.012) g/L, IgM (0.012 ±0.011) g/L]and the severe group [IgG (0.128 ±0.112) g/L, IgA (0.015 ± 0.011) g/L, IgM (0.013±0.013) g/L](P>0.05).There was no correlation between the levels of CSF-Ig and DcR3 mRNA (rIgG = 0.0083, rIgA = 0.0056, rIgM = 0.0015, P> 0.05).Conclusions The expression of DcR3 mRNA in PBMCs increased significantly in GBS patients, indicating that DcR3 could be involved in the pathogenesis of GBS.There was no correlation between GBS severity and DcR3 mRNA level or between CSF-Ig and DcR3 mRNA levels.%目的 研究吉兰-巴雷综合征(Guillain-Barré syndrome,GBS)患者外周血单个核细胞(PBMCs)中凋亡相关基因诱骗受体(DCR3)mRNA的表达水平.探讨DcR3与GBS疾病严重程度及脑脊液免疫球蛋白(CSFIg,包括IgG、IgA、IgM)水平之间的关联性.方法 以36例GBS患者和20名健康人为研究对象,应用反转录聚合酶链反应(RT-PCR)检测外周静脉血PBMCs DcR3 mRNA表达水平,并对GBS患者CSF-Ig水平与疾病严重程度和DcR3 mRNA表达的相关性进行分析.结果 GBS

  12. 寻常型银屑病患者外周血单个核细胞SOCS-1、SOCS-3 mRNA的表达%The expression of SOCS-1 and SOCS-3 mRNA in patients with psoriasis vulgaris

    Institute of Scientific and Technical Information of China (English)

    郭红卫; 王京滨; 李国明; 李顺凡; 吴志华

    2007-01-01

    目的: 检测细胞因子信号抑制因子SOCS-1、SOCS-3 mRNA在寻常型银屑病患者外周血单个核细胞(PBMC)中的表达.方法: 从20例银屑病患者及20例健康志愿者外周血中分离PBMC,提取RNA,应用逆转录-聚合酶链反应(RT-PCR)方法检测SOCS-1、SOCS-3 mRNA的表达.结果: SOCS-1、SOCS-3 mRNA在银屑病患者中表达,在正常人中无表达,活动期银屑病患者较静止期患者SOCS-1、SOCS-3 mRNA表达增高.结论: SOCS-1、SOCS-3可能在银屑病的Th1免疫反应中发挥作用.

  13. FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis

    DEFF Research Database (Denmark)

    Ryder, L. Rebekka; Bartels, Else Marie; Woetmann, Anders;

    2012-01-01

    Our aim was to elucidate the relative amount of the different splice forms of FoxP3 mRNA in CD4+ T cells in peripheral blood (PB) compared to synovial fluid (SF) in RA and PsA patients. FoxP3 mRNA was measured using a quantitative real-time PCR method. CD4+ T cells were isolated from 17 paired...... samples of PB and SF from RA and PsA patients, and PB from 10 controls. FoxP3fl and FoxP3Δ2 mRNA was significantly increased (6.7 and 2.1-fold, respectively) in PB CD4+ T cells from RA patients compared to controls. FoxP3fl and Δ2 mRNA in SF CD4+ T cells was increased compared to controls in sero......-negative RA and PsA, but not in sero-positive RA patients, who had a high FoxP3 expression in both PB and SF. The FoxP3Δ2Δ7 mRNA was barely detectable in patient samples, and not at all in healthy individuals. We provide evidence of an increased expression of FoxP3 splice forms in synovial CD4+ T cells from...

  14. Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel

    Directory of Open Access Journals (Sweden)

    Uysal-Onganer Pinar

    2007-11-01

    Full Text Available Abstract Background Although a high level of functional voltage-gated sodium channel (VGSC expression has been found in strongly metastatic human and rat prostate cancer (PCa cells, the mechanism(s responsible for the upregulation is unknown. The concentration of epidermal growth factor (EGF, a modulator of ion channels, in the body is highest in prostatic fluid. Thus, EGF could be involved in the VGSC upregulation in PCa. The effects of EGF on VGSC expression in the highly metastatic human PCa PC-3M cell line, which was shown previously to express both functional VGSCs and EGF receptors, were investigated. A quantitative approach, from gene level to cell behaviour, was used. mRNA levels were determined by real-time PCR. Protein expression was studied by Western blots and immunocytochemistry and digital image analysis. Functional assays involved measurements of transverse migration, endocytic membrane activity and Matrigel invasion. Results Exogenous EGF enhanced the cells' in vitro metastatic behaviours (migration, endocytosis and invasion. Endogenous EGF had a similar involvement. EGF increased VGSC Nav1.7 (predominant isoform in PCa mRNA and protein expressions. Co-application of the highly specific VGSC blocker tetrodotoxin (TTX suppressed the effect of EGF on all three metastatic cell behaviours studied. Conclusion 1 EGF has a major involvement in the upregulation of functional VGSC expression in human PCa PC-3M cells. (2 VGSC activity has a significant intermediary role in potentiating effect of EGF in human PCa.

  15. The SF3M approach to 3-D photo-reconstruction for non-expert users: application to a gully network

    Science.gov (United States)

    Castillo, C.; James, M. R.; Redel-Macías, M. D.; Pérez, R.; Gómez, J. A.

    2015-04-01

    3-D photo-reconstruction (PR) techniques have been successfully used to produce high resolution elevation models for different applications and over different spatial scales. However, innovative approaches are required to overcome some limitations that this technique may present in challenging scenarios. Here, we evaluate SF3M, a new graphical user interface for implementing a complete PR workflow based on freely available software (including external calls to VisualSFM and CloudCompare), in combination with a low-cost survey design for the reconstruction of a several-hundred-meters-long gully network. SF3M provided a semi-automated workflow for 3-D reconstruction requiring ~ 49 h (of which only 17% required operator assistance) for obtaining a final gully network model of > 17 million points over a gully plan area of 4230 m2. We show that a walking itinerary along the gully perimeter using two light-weight automatic cameras (1 s time-lapse mode) and a 6 m-long pole is an efficient method for 3-D monitoring of gullies, at a low cost (about EUR 1000 budget for the field equipment) and time requirements (~ 90 min for image collection). A mean error of 6.9 cm at the ground control points was found, mainly due to model deformations derived from the linear geometry of the gully and residual errors in camera calibration. The straightforward image collection and processing approach can be of great benefit for non-expert users working on gully erosion assessment.

  16. New rock salt-related oxides Li{sub 3}M{sub 2}RuO{sub 6} (M=Co, Ni): Synthesis, structure, magnetism and electrochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Laha, S. [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012 (India); Morán, E., E-mail: emoran@quim.ucm.es [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Sáez-Puche, R.; Alario-Franco, M.Á.; Dos santos-Garcia, A.J. [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Gonzalo, E.; Kuhn, A.; García-Alvarado, F. [Universidad CEU San Pablo, Facultad de Farmacia, Departamento de Química, 28668 Boadilla del Monte, Madrid (Spain); Sivakumar, T.; Tamilarasan, S.; Natarajan, S.; Gopalakrishnan, J. [Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012 (India)

    2013-07-15

    We describe the synthesis, crystal structure, magnetic and electrochemical characterization of new rock salt-related oxides of formula, Li{sub 3}M{sub 2}RuO{sub 6} (M=Co, Ni). The M=Co oxide adopts the LiCoO{sub 2} (R-3m) structure, where sheets of LiO{sub 6} and (Co{sub 2}/Ru)O{sub 6} octahedra are alternately stacked along the c-direction. The M=Ni oxide also adopts a similar layered structure related to Li{sub 2}TiO{sub 3}, where partial mixing of Li and Ni/Ru atoms lowers the symmetry to monoclinic (C2/c). Magnetic susceptibility measurements reveal that in Li{sub 3}Co{sub 2}RuO{sub 6}, the oxidation states of transition metal ions are Co{sup 3+} (S=0), Co{sup 2+} (S=1/2) and Ru{sup 4+} (S=1), all of them in low-spin configuration and at 10 K, the material orders antiferromagnetically. Analogous Li{sub 3}Ni{sub 2}RuO{sub 6} presents a ferrimagnetic behavior with a Curie temperature of 100 K. The differences in the magnetic behavior have been explained in terms of differences in the crystal structure. Electrochemical studies correlate well with both magnetic properties and crystal structure. Li-transition metal intermixing may be at the origin of the more impeded oxidation of Li{sub 3}Ni{sub 2}RuO{sub 6} when compared to Li{sub 3}Co{sub 2}RuO{sub 6}. Interestingly high first charge capacities (between ca. 160 and 180 mAh g{sup −1}) corresponding to ca. 2/3 of theoretical capacity are reached albeit, in both cases, capacity retention and cyclability are not satisfactory enough to consider these materials as alternatives to LiCoO{sub 2}. - Graphical abstract: Two new rock salt related oxides of formula, Li{sub 3}M{sub 2}RuO{sub 6}, (M=Co, Ni) have been prepared. The M=Co oxide adopts the LiCoO{sub 2} (R-3m) structure and the M=Ni oxide adopts a similar layered structure related to Li{sub 2}TiO{sub 3,} monoclinic (C2/c), with partial mixing of Li and Ni/Ru atoms. For Li{sub 3}Co{sub 2}RuO{sub 6}, oxidation state for Ru is 4+ and antiferromagnetic (AFM) order is

  17. Expression and significance of T - bet mRNA and GATA3 mRNA of preeclampsia patients' decidua basalis%T-bet mRNA和GATA3 mRNA在子痫前期蜕膜组织中的表达

    Institute of Scientific and Technical Information of China (English)

    田晓瑜; 杨海澜; 何银芳

    2012-01-01

    Objective: To investigate the different expression of various in decidua basalis between preeclampsia and normal pregnant women. Methods; The patients with preeclampsia and normot ensive of late pregnancy were selected as study group and control group. The levels of T - bet mRNA and GATA3 mRNA in both group were measured by RT - PCR. Results: ①The levels of T - bet mRNA were significant differences between severe preeclampsia group and normal pregnancy group, severe preeclampsia group and mild preeclampsia group (P <0.01, P <0.01 ). There was no significantly statistical difference between mild preeclampsia group and normal pregnancy group (P = 0. 089). ②The levels of GATA3 mRNA were significant differences between severe preeclampsia group and normal pregnancy group, severe preeclampsia group and Mild preeclampsia group (P < 0.01, P < 0.01). There was no significantly statistical difference between mild preeclampsia group and normal pregnancy group (P = 0.127). ③The ratio of T - bet mRNA and GATA3 mRNA were differerces between severe preeclampsia group and normal pregnancy group, severe preeclampsia group and mild preeclampsia group (P < 0.01, P < 0.01). The difference of The ratio of T - bet mRNA and GATA3 mRNA among mild preeclampsia group and normal pregnancy group were no statistically significant (P = 0. 322). Conclusions: The disbalant expression levels of T - bet mRNA and GATA - 3 mRNA may be lead to the shift of Th1 in preeclampsia.%目的 探讨T - bet mRNA和GATA3 mRNA在正常妊娠产妇及子痫前期患者蜕膜组织中的表达差异.方法 选取子痫前期和正常妊娠产妇作为实验组和对照组,采用RT - PCR方法,检测各组产妇蜕膜组织中T- bet mRNA和GA-TA3mRNA表达水平.结果 ①子痫前期重度组与轻度组相比,子痫前期重度组与正常组相比T- bet mRNA表达量的差异有统计学意义(P<0.01,P<0.01).子痫前期轻度组与正常组T- bet mRNA表达量相比较差异无统计学意义(P=0

  18. Zygote arrest 1, nucleoplasmin 2, and developmentally associated protein 3 mRNA profiles throughout porcine embryo development in vitro.

    Science.gov (United States)

    Wasielak, M; Więsak, T; Bogacka, I; Jalali, B Moza; Bogacki, M

    2016-12-01

    Maternal effect genes (MEGs) are expressed in oocytes and embryos and play an important role in activation of the embryonic genome. An abnormality in the expression of these genes may lead to arrest of embryonic cleavage or to altered transcription of factors responsible for further embryonic development. In vitro-produced porcine embryos have a lower developmental potential than embryos produced in vivo. We hypothesized that in vitro embryo culture conditions have an effect on the expression of MEGs at various developmental stages, which may affect their developmental potential. Here, using real-time polymerase chain reaction, we examined mRNA profiles of the MEGs, zygote arrest 1 (ZAR-1), nucleoplasmin 2 (NPM2), and developmentally associated pluripotency protein 3 (DPPA3), in porcine oocytes and embryos produced in vitro and in vivo. Further, we evaluated the effect of the combined addition of EGF, interleukin 1β, and leukemia inhibitory factor to the porcine in vitro embryo production system on mRNA profiles of selected MEGs. Finally, we studied localization of the MEG protein products in in vitro-obtained oocytes and embryos using confocal microscopy. We found that the ZAR-1 mRNA profile differed throughout in vitro and in vivo embryo development. In the embryos produced in vitro, the decrease in ZAR-1 mRNA levels was observed at the 2-cell stage, whereas in in vivo embryos, ZAR-1 mRNA levels declined significantly starting at the 4-cell stage (P vitro culture conditions affected transiently also DPPA3 mRNA levels at the 4-cell stage (P vitro and in vivo embryo development. The ZAR-1 and DPPA3 proteins were localized in the cytoplasm of the oocytes and embryos, whereas the NPM2 protein was found both in the cytoplasm and in the nucleus. All proteins were expressed until blastocyst stage. The addition of EGF and cytokines to the culture medium decreased DPPA3 mRNA levels in 8-cell embryos (P < 0.05). This study indicated that IVC conditions

  19. Expression of nerve growth factor and neurotrophin-3 mRNAs in hippocampal interneurons: morphological characterization, levels of expression, and colocalization of nerve growth factor and neurotrophin-3.

    Science.gov (United States)

    Pascual, M; Rocamora, N; Acsády, L; Freund, T F; Soriano, E

    1998-05-25

    We have investigated the distribution and morphology of hippocampal interneurons that express the neurotrophins nerve growth factor (NGF) and neurotrophin-3 (NT-3) in the rat. For this study, we combined in situ hybridization for the detection of NGF and NT-3 mRNAs and immunocytochemistry against the calcium-binding proteins parvalbumin (PARV), calretinin (CALR), and calbindin (CALB). Whereas the majority of PARV+ interneurons expressed NGF mRNA, only subsets of CALR- and CALB-immunoreactive interneurons (23% and 24%, respectively) displayed NGF hybridization. Most CALB/NGF+ cells were located in the stratum oriens/alveus of the CA3-CA1 regions, suggesting that they may include the population of CALB+, hippocamposeptal, nonpyramidal neurons. Most of the nonspiny CALR/NGF+ neurons were located within or in the vicinity of the pyramidal layer and had faint CALR immunostaining and stellate, thin dendrites. Regarding the spiny CALR-immunoreactive cells, we found that most of these neurons in the hilus were NGF+, whereas only 59% of displayed NGF hybridization in the stratum lucidum of the CA3 region. A small subset of PARV- and CALR-immunoreactive cells expressed NT-3 mRNA (16% and 13%, respectively). NT-3 message was not found in the large basket cells of the dentate gyrus, whereas the distribution and morphology of CALR/NT-3+ cells were similar to those of nonspiny CALR/NGF+ cells. In fact, double in situ hybridization analysis confirmed that most NT-3+ neurons also expressed NGF mRNA, indicating coexpression of both neurotrophins in subpopulations of PARV+ and CALR+ neurons. Moreover, the level of NGF mRNA expression was higher in PARV+ neurons than in CALR- and CALB-immunoreactive interneurons, whereas NT-3 message was expressed similarly in PARV+ and CALR+ neurons. The present findings show a differential expression of NGF and NT-3 mRNAs in subsets of hippocampal interneurons and suggest that the expression of these transcripts depends on factors intrinsic to

  20. Entre las promesas y los resultados: notas sobre los retos de futuro de la TDT

    OpenAIRE

    García Leiva, María Trinidad

    2011-01-01

    Este artículo es resultado de la actividad desarrollada en el marco del grupo de investigación TECMERIN, de la UC3M. El objetivo del artículo es plantear una reflexión general sobre los retos futuros de la red digital terrestre de difusión de señales audiovisuales partiendo de un balance de las promesas vinculadas a su introducción hace más de una década y su contracara de resultados palpables. En función de las derivaciones potenciales que el escenario actual presenta se analizarán pues s...

  1. Yellow phosphors doping with Gd3+, Tb3+ and Lu3+ in MTiO3 (M = Mg and Sr) luminescence properties

    Indian Academy of Sciences (India)

    Esra Korkmaz; Nilgun Ozpozan Kalaycioglu; V Emir Kafadar

    2013-11-01

    This paper reports Gd3+, Tb3+ and Lu3+ doped MTiO3 (M = Mg and Sr)-based phosphors which were synthesized by the conventional solid-state reaction method, their crystal structures and luminescence properties were investigated. X-ray diffraction patterns (XRD) showed that phosphors sintered at 1000 °C for 2 h were the pure SrTiO3 and MgTiO3 phases. The optimization of reaction conditions was carried out by thermogravimetry and differential thermal analysis (DTA/TG) methods. Surface and elemental analyses were performed by using SEM instrument. The excitation and emission spectra were recorded by a photoluminescence spectrophotometer (PL). The thermoluminescence (TL) properties of MgTiO3:RE (RE = Gd3+, Tb3+, Lu3+) and SrTiO3:RE (RE = Gd3+, Tb3+, Lu3+) were investigated.

  2. Commissioning ShARCS: the Shane Adaptive optics infraRed Camera-Spectrograph for the Lick Observatory 3-m telescope

    CERN Document Server

    McGurk, Rosalie; Gavel, Donald; Kupke, Renate; Peck, Michael; Pfister, Terry; Ward, Jim; Deich, William; Gates, John; Gates, Elinor; Alcott, Barry; Cowley, David; Dillon, Daren; Lanclos, Kyle; Sandford, Dale; Saylor, Mike; Srinath, Srikar; Weiss, Jason; Norton, Andrew

    2014-01-01

    We describe the design and first-light early science performance of the Shane Adaptive optics infraRed Camera-Spectrograph (ShARCS) on Lick Observatory's 3-m Shane telescope. Designed to work with the new ShaneAO adaptive optics system, ShARCS is capable of high-efficiency, diffraction-limited imaging and low-dispersion grism spectroscopy in J, H, and K-bands. ShARCS uses a HAWAII-2RG infrared detector, giving high quantum efficiency (>80%) and Nyquist sampling the diffraction limit in all three wavelength bands. The ShARCS instrument is also equipped for linear polarimetry and is sensitive down to 650 nm to support future visible-light adaptive optics capability. We report on the early science data taken during commissioning.

  3. 3M Petrifilm Staph Express Count plate method for the enumeration of Staphylococcus aureus in selected types of meat, seafood, and poultry: collaborative study.

    Science.gov (United States)

    McMahon, Wendy A; Aleo, Victoria A; Schultz, Ann M; Horter, Barbara L; Lindberg, Kathryn G

    2003-01-01

    The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Four foods--cooked, diced chicken; cured ham; smoked salmon; and pepperoni--were analyzed for S. aureus by 12 collaborating laboratories. For each food tested, the collaborators received 8 blind test samples consisting of a control sample, a low inoculation level, a medium inoculation level, and a medium inoculation level with background flora, each in duplicate. The mean log10 counts for the methods were comparable for all 4 foods. The repeatability and reproducibility variances of the 24 h Petrifilm Staph Express Count plate method were similar to those of the 72 h standard method.

  4. 3M Petrifilm Staph Express Count plate method for the enumeration of Staphylococcus aureus in selected types of processed and prepared foods: collaborative study.

    Science.gov (United States)

    Silbernagel, Karen M; Jechorek, Robert P; Carver, Charles N; Horter, Barbara L; Lindberg, Kathryn G

    2003-01-01

    The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Five foods--frozen lasagna, custard, frozen mixed vegetables, frozen hashbrowns, and frozen batter-coated mushrooms--were analyzed for S. aureus by 13 collaborating laboratories. For each food tested, the collaborators received 8 blind test samples consisting of a control sample, a low inoculation level, a medium inoculation level, and a medium inoculation level with background flora, each in duplicate. The mean log10 counts for the methods were comparable for all 5 foods. The repeatability and reproducibility variances of the 24 h Petrifilm Staph Express Count plate method were similar to those of the 72 h standard method.

  5. Accuracy assessment of NOGGIN Plus and MALÅ RAMAC X3M single channel ground penetrating RADAR (GPR) for underground utility mapping

    Science.gov (United States)

    Sazali Hashim, Mas; Nizam Saip, Saiful; Hani, Nurfauziah; Pradhan, Biswajeet; Abdullahi, Saleh

    2016-06-01

    Ground Penetrating Radar (GPR) becomes a popular device in investigation of the underground utilities in recent years. GPR analyses the type and position of utility objects. However, the performance accuracy of GPR models is an important issue that should be considered. This study conducts the accuracy analysis between two models of single channel GPR; NOGGIN PLUS and MALÅ RAMAC X3M, by focusing on the basic principles of single channel GPR, accuracy analysis and calibration methods implemented on GPR. The survey work has been performed to identify the most accurate instrument to detect underground utility objects. In addition, data analysis was carried out to compare between two models of single channel GPR. This study provides proper guidelines and assists surveyors to select the suitable instruments regarding on applications especially on utility mapping in terms of accuracy.

  6. Magnetic and Mechanical Properties of Hard Magnetic Alloys 30Kh21K3M and 30Kh20K2M2V

    Science.gov (United States)

    Stel'mashok, S. I.; Milyaev, I. M.; Yusupov, V. S.; Milyaev, A. I.

    2017-01-01

    The magnetic and mechanical properties of two hard magnetic alloys (30Kh21K3M and 30Kh20K2M2V) of the Fe - Cr - Co system in anisotropic and isotropic conditions produced by traditional induction melting and by the method of powder metallurgy with subsequent pressure treatment of the metal are studied. The obtained regression equations for B r , H cB and ( BH )max describe the quantities adequately in the used range of variation of factors. The response surfaces and their sections in the phase space of the heat treatment factors are plotted. The results of the analysis of the proportion of residual induction in anisotropic and isotropic states are used to infer that the model of the mechanism of magnetization reversal of hard magnetic alloys of the class considered needs amending.

  7. Adaptation of a four-wall interference assessment/correction procedure for airfoil tests in the 0.3-m TCT

    Science.gov (United States)

    Gumbert, C. R.; Newman, P. A.; Kemp, W. B., Jr.; Adcock, J. B.

    1984-01-01

    Based upon limited, initial observations of wall interference corrections obtained for one airfoil test, there is a need for assessing the upstream flow direction. If there is no direct measurement then a two-pass correction procedure similar to the one described here is required. Questions have arisen pertaining to the correct interpretation of the pressure coefficients measured on the slats of a slotted tunnel wall, the interpretation of just what the calculated equivalent body encompasses or should include, and what can or should be considered as quantitative criteria for data correctability. Further studies using this modified procedure will address these questions. Hopefully, a meaningful WIAC procedure can be validated for the airfoil tests in the 0.3-m TCT.

  8. Synthesis, structure and dielectric properties of Ba1-xSrx My Ti1-yO3 (M = Zr, Sn)

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A series of Ba1-xSrxMyTi1-yO3 (M = Zr, Sn, 0≤x≤0.4, 0≤y≤0.3) solid solutions were synthesized with the soft chemical method below 100 ° C. XRD pattern and cell parameters- composition figures of the prepared powder demonstrate that they are completely miscible solid solutions based on BaTiO3. Furthermore, TEM shows that they have a shape of uniform, substantially spherical particles with an average particle size of 70 nm in diameter. The sintered ceramics of the powder doped with Sr2+ and Zr4+ or Sn4+ have dielectric constant eight times higher and dielectric loss thirty per cent lower than those of pure BaTiO3 phase at room temperature.

  9. Identification of hyperhalogens in Ag(n)(BO2)(m) (n = 1-3, m = 1-2) clusters: anion photoelectron spectroscopy and density functional calculations.

    Science.gov (United States)

    Kong, Xiang-Yu; Xu, Hong-Guang; Koirala, Pratik; Zheng, Wei-Jun; Kandalam, Anil K; Jena, Puru

    2014-12-21

    The electronic and structural properties of neutral and anionic Agn(BO2)m (n = 1-3, m = 1-2) clusters are investigated by using mass-selected anion photoelectron spectroscopy and density functional theory calculations. Agreement between the measured and calculated vertical detachment energies (VDEs) allows us to validate the equilibrium geometries of [Agn(BO2)m](-) clusters obtained from theory. The ground state structures of anionic Ag2(BO2) and Agn(BO2)2 (n = 1-3) clusters are found to be very different from those of their neutral counterparts. The structures of anionic clusters are chain-like while those of the neutral clusters are closed-rings. The presence of multiple isomers for [Ag2(BO2)2](-) and [Ag3(BO2)2](-) in the cluster beam has also been confirmed. Several of these clusters are found to be hyperhalogens.

  10. β-catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase M3 mRNA

    Institute of Scientific and Technical Information of China (English)

    Yu-Sang Li; Min Liu; Yoshihiro Nakata; He-Bin Tang

    2011-01-01

    AIM: To identify the differentially over-expressed genes associated with β-catenin accumulation in nuclei of hepatocellular carcinoma (HCC) cells.METHODS: Differentially expressed genes were identified in radiation-induced B6C3 F1 mouse HCC cells by mRNA differential display, Northern blot and RT-PCR,respectively. Total glutathione-s-transferase (GST) activity was measured by GST activity assay and β-catenin localization was detected with immunostaining in radiation-induced mouse HCC cells and in HepG2 cell lines.RESULTS: Two up-regulated genes, glutamine synthetase and glutathione-s-transferase M3 (GSTM3), were identified in radiation-induced mouse HCC cells. Influence of β-catenin accumulation in nuclei of HCC cells on upregulation of GSTM3 mRNA was investigated. The nearby upstream domain of GSTM3 contained the β-catenin/Tcf-Lef consensus binding site sequences [5'-(A/T)(A/T)CAAAG-3'], and the total GST activity ratio was considerably higher in B6C3F1 mouse HCC cells with β-cateninaccumulation in nuclei of HCC cells than in those withoutβ-catenin accumulation (0.353 ± 0.117 vs 0.071 ± 0.064,P < 0.001). The TWS119 (a distinct GSK-3β inhibitor)-induced total GST activity was significantly higher in HepG2 cells with β-catenin accumulation than in those withoutβ-catenin accumulation in nuclei of HCC cells. Additionally,the GSTM3 mRNA level was significantly higher at 24 h than at 12 h in TWS119-treated HepG2 cells.CONCLUSION: β-catenin accumulation increases GST activity in nuclei of HCC cells, and GSTM3 may be a novel target gene of the β-catenin/Tcf-Lef complex.

  11. SF3M software: 3-D photo-reconstruction for non-expert users and its application to a gully network

    Science.gov (United States)

    Castillo, C.; James, M. R.; Redel-Macías, M. D.; Pérez, R.; Gómez, J. A.

    2015-08-01

    Three-dimensional photo-reconstruction (PR) techniques have been successfully used to produce high-resolution surface models for different applications and over different spatial scales. However, innovative approaches are required to overcome some limitations that this technique may present for field image acquisition in challenging scene geometries. Here, we evaluate SF3M, a new graphical user interface for implementing a complete PR workflow based on freely available software (including external calls to VisualSFM and CloudCompare), in combination with a low-cost survey design for the reconstruction of a several-hundred-metres-long gully network. SF3M provided a semi-automated workflow for 3-D reconstruction requiring ~ 49 h (of which only 17 % required operator assistance) for obtaining a final gully network model of > 17 million points over a gully plan area of 4230 m2. We show that a walking itinerary along the gully perimeter using two lightweight automatic cameras (1 s time-lapse mode) and a 6 m long pole is an efficient method for 3-D monitoring of gullies, at a low cost (~ EUR 1000 budget for the field equipment) and the time requirements (~ 90 min for image collection). A mean error of 6.9 cm at the ground control points was found, mainly due to model deformations derived from the linear geometry of the gully and residual errors in camera calibration. The straightforward image collection and processing approach can be of great benefit for non-expert users working on gully erosion assessment.

  12. Granzyme B-dependent and perforin-independent DNA fragmentation in intestinal epithelial cells induced by anti-CD3 mAb-activated intra-epithelial lymphocytes.

    Science.gov (United States)

    Ogata, Masaki; Ota, Yuta; Matsutani, Takaji; Nanno, Masanobu; Suzuki, Ryuji; Itoh, Tsunetoshi

    2013-05-01

    We previously found that an i.p. injection of anti-CD3 monoclonal antibody (mAb) into mice caused DNA fragmentation in the intestinal villous epithelial cells (IVECs) of the duodenum and the jejunum. In this study, in order to elucidate the mechanism of DNA fragmentation in IVECs, we searched for the inducer(s) of DNA fragmentation by using immunohistochemistry. The release of cytoplasmic granules from intraepithelial lymphocytes (IELs) and the formation of large gaps between IELs and IVECs were observed electron microscopically after antibody administration. The presence and distribution pattern of Granzyme B (GrB), a serine protease in cytolytic granules present in cytotoxic T lymphocytes and natural killer cells and considered to be the responsible molecule for DNA fragmentation in target cells, was examined in detail in intestinal villi by immunohistology. GrB was detected in cytoplasmic granules in nearly all IELs. The time-kinetics of granule release from IELs after mAb injection coincided not only with that of the extracellular diffusion of GrB, but also with that of DNA fragmentation in IVECs. On the other hand, perforin (Pfn), assumed to cooperate with GrB in DNA fragmentation, could not be detected in IELs, and its release was not confirmed after the anti-CD3 mAb injection. Anti-CD3 mAb injection also induced DNA fragmentation in IVECs in Pfn-knockout mice. These results support the notion that DNA fragmentation in IVECs by the stimulated IELs in the present study is induced by a mechanism involving GrB, but independent of Pfn.

  13. Divergence of Pumilio/fem-3 mRNA binding factor (PUF) protein specificity through variations in an RNA-binding pocket.

    Science.gov (United States)

    Qiu, Chen; Kershner, Aaron; Wang, Yeming; Holley, Cynthia P; Wilinski, Daniel; Keles, Sunduz; Kimble, Judith; Wickens, Marvin; Hall, Traci M Tanaka

    2012-02-24

    mRNA control networks depend on recognition of specific RNA sequences. Pumilio-fem-3 mRNA binding factor (PUF) RNA-binding proteins achieve that specificity through variations on a conserved scaffold. Saccharomyces cerevisiae Puf3p achieves specificity through an additional binding pocket for a cytosine base upstream of the core RNA recognition site. Here we demonstrate that this chemically simple adaptation is prevalent and contributes to the diversity of RNA specificities among PUF proteins. Bioinformatics analysis shows that mRNAs associated with Caenorhabditis elegans fem-3 mRNA binding factor (FBF)-2 in vivo contain an upstream cytosine required for biological regulation. Crystal structures of FBF-2 and C. elegans PUF-6 reveal binding pockets structurally similar to that of Puf3p, whereas sequence alignments predict a pocket in PUF-11. For Puf3p, FBF-2, PUF-6, and PUF-11, the upstream pockets and a cytosine are required for maximal binding to RNA, but the quantitative impact on binding affinity varies. Furthermore, the position of the upstream cytosine relative to the core PUF recognition site can differ, which in the case of FBF-2 originally masked the identification of this consensus sequence feature. Importantly, other PUF proteins lack the pocket and so do not discriminate upstream bases. A structure-based alignment reveals that these proteins lack key residues that would contact the cytosine, and in some instances, they also present amino acid side chains that interfere with binding. Loss of the pocket requires only substitution of one serine, as appears to have occurred during the evolution of certain fungal species.

  14. Density functional theory studies on theelectronic, structural, phonon dynamicaland thermo-stability properties of bicarbonates MHCO3, M D Li, Na, K

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Yuhua; Zhang, Bo; Sorescu, Dan C.; Johnson, Karl; Majzoub, Eric H; Luebke, David R.

    2012-07-01

    The structural, electronic, phonon dispersion and thermodynamic properties of MHCO3 (M D Li, Na, K) solids were investigated using density functional theory. The calculated bulk properties for both their ambient and the high-pressure phases are in good agreement with available experimental measurements. Solid phase LiHCO3 has not yet been observed experimentally. We have predicted several possible crystal structures for LiHCO3 using crystallographic database searching and prototype electrostatic ground state modeling. Our total energy and phonon free energy .FPH/ calculations predict that LiHCO3 will be stable under suitable conditions of temperature and partial pressures of CO2 and H2O. Our calculations indicate that the HCO 3 groups in LiHCO3 and NaHCO3 form an infinite chain structure through O H O hydrogen bonds. In contrast, the HCO 3 anions form dimers, .HCO 3 /2, connected through double hydrogen bonds in all phases of KHCO3. Based on density functional perturbation theory, the Born effective charge tensor of each atom type was obtained for all phases of the bicarbonates. Their phonon dispersions with the longitudinal optical–transverse optical splitting were also investigated. Based on lattice phonon dynamics study, the infrared spectra and the thermodynamic properties of these bicarbonates were obtained. Over the temperature range 0–900 K, the FPH and the entropies (S) of MHCO3 (M D Li, Na, K) systems vary as FPH.LiHCO3/ > FPH.NaHCO3/ > FPH.KHCO3/ and S.KHCO3/ > S.NaHCO3/ > S.LiHCO3/, respectively, in agreement with the available experimental data. Analysis of the predicted thermodynamics of the CO2 capture reactions indicates that the carbonate/bicarbonate transition reactions for Na and K could be used for CO2 capture technology, in agreement with experiments.

  15. Establishmant of a real-time fluorescent quantitative method far detection of VEGF-C mRNA/VEGFR-3mRNA expression and its application%VEGF-C mRNA和VEGFR-3 mRNA实时荧光定量检测方法的建立及初步应用

    Institute of Scientific and Technical Information of China (English)

    卢培; 陆慧琦; 韩焕兴; 朱学源; 黄秋芳; 龚炜

    2009-01-01

    Objective To establish a real-time fluorescent quantitative reverse transcription pol-ymerase chain reaction (FQ-RT-PCR) method for detecting the expression levels of VEGF-C mRNA and VEGFR-3 mRNA,and explore its clinical application in esophageal carcinoma. Methods The real-time FQ-RT-PCR for detecting VEGF-C mRNA and VEGFR-3 mRNA was espabished based on Taq-Man fluorescent probe technology. In this method pMD18-VEGF-C and pMD18-VEGFR-3 were used as standard plasmid and RNA quantification was based on the threshold cycle (Ct) values to examine the specific expression of VEGF-C mRNA and VEGFR-3 mRNA in esophageal carcinoma. Results The detection linear range of the assay: VEGF-CmRNA and VEGFR-3 mRNA was both 103~ 108 copies/μg total RNA. The interassay and intraassay coefficient o{ variation of VEGF-C mRNA lower value was 7.07% and 9.04% respectively,7.55% and 10.28% for higher value respectively; the in-terassay and intraassay coefficient of variation of VEGFR-3 mRNA lower value was 7.69% and 12. 49% respectively,7.31% and 0.17%for higher value respectively. TheVEGF-C mRNA and theVEGFR-3 mRNA range in carcinoma tissue from 24 patients with lymphatic metastasis of esophageal carcinoma was 3.69×104-9.44 × 106 copies/μg total RNA and 2.54 × 104-8.03 × 106 copies/μg total RNA respectively, the mean value was 2.18 × 106 copies/μg total RNA and 2.27 × 106 copies/μg total RNA respectively. The VEGF-C mRNA and VEGFR-3 mRNA range in carcinoma tissue from 16 pa-tients without lymphatic metastasis of esophageal carcinoma was 2.32 × 103-5.85 × 105 copies/μg total RNA and 7.31 × 102-8.21 × 104 copies/μg total RNA respectively,the mean value was 1.08×105 cop-ies/μg total RNA and 1.68 ×104 copies/μg total RNA respectively. The VEGF-C mRNA and VEGFR-3 mRNA copy number per microgram of total RNA in carcinoma tissue from patients with lymphatic metastasis of esophageal carcinoma was significantly higher than that in carcinoma tissue from patients without

  16. Representaciones sociales juveniles sobre la democracia

    Directory of Open Access Journals (Sweden)

    Álvaro Díaz Gómez

    2005-01-01

    Full Text Available El presente artículo da cuenta de una parte de los resultados obtenidos en la investigación “representaciones sociales juveniles sobre la democracia y la multiculturalidad”. Se desarrolló desde la perspectiva metodológica de la Investigación Acción Participante, proceso dentro del cual, se aplicó un cuestionario conformado por nueve preguntas, divididas en tres bloques temáticos que permitieron conocer las representaciones sociales de un grupo de veinticinco jóvenes, sobre la democracia –aspecto que se reporta en este texto– la ciudadanía y la multiculturalidad a partir de tres dimensiones: significado, vivencias y condiciones de la democracia.

  17. Sobre lectura y escritura en Chile

    OpenAIRE

    Grínor Rojo

    2011-01-01

    Los estudios de los últimos años realizados en Chile sobre lectura, competencia de lectura y lectura de noticias sobre política, revelan valores negativos que rondan el 50. Estos datos, a los que se suman los cuarenta millones de analfabetos en América Latina, están en la base del rechazo en este artículo de la afirmación de la muerte del libro y de la frívola fe en el reemplazo del libro por el uso de las tecnologías de la información y la comunicación (llenar de computadoras las escuelas), ...

  18. Observaciones sobre didáctica

    Directory of Open Access Journals (Sweden)

    Alfonso Tamayo Valencia

    2014-02-01

    Full Text Available  En el presente artículo, a partir de la conceptualización sobre didáctica y enseñanza, se plantean sus posibilidades en la educación superior, especialmente cuando reflexionamos en las prácticas de enseñanza desde un saber hacer que supere el hacer de esquemas tácitos y espontáneos que caracteriza en buena parte docencia universitaria. Desde esta perspectiva se aboga por la renovación de la concepción de la didáctica desde una postura epistemológica y psicológica sobre la manera como se construye el conocimiento.

  19. Sobre lectura y escritura en Chile

    Directory of Open Access Journals (Sweden)

    Grínor Rojo

    2012-11-01

    Full Text Available Los estudios de los últimos años realizados en Chile sobre lectura, competencia de lectura y lectura de noticias sobre política, revelan valores negativos que rondan el 50. Estos datos, a los que se suman los cuarenta millones de analfabetos en América Latina, están en la base del rechazo en este artículo de la afirmación de la muerte del libro y de la frívola fe en el reemplazo del libro por el uso de las tecnologías de la información y la comunicación (llenar de computadoras las escuelas, insistiendo en cambio en atender seriamente a los lazos entre razón, libro y lectura en el desarrollo individual y de la sociedad

  20. Radiaciones ionizantes y efectos sobre la materia

    Directory of Open Access Journals (Sweden)

    Sandra Magaly Medina Araujo

    2002-01-01

    Full Text Available Las radiaciones ionizantes, además, de tener muchas aplicaciones benéficas tanto en el campo industrial como en los organismos vivientes, presentan también muchos efectos nocivos que se deben evitar, sobre todo cuando se trata de fuentes artificiales con las que pueden presentarse abusos en su utilización, especialmente en la parte clínica. Este artículo, el primero de una serie de divulgaciones acerca del tema, pretende dar a conocer las características y efectos sobre la materia, de las mencionadas radiaciones, así como algunas recomendaciones acerca del manejo y tralAS, tamiento de dichas radiaciones

  1. Sobre la felicidad y la ataraxia

    Directory of Open Access Journals (Sweden)

    Alberto Londoño Alvarez

    1969-09-01

    Full Text Available Muy pocos lectores, seguramente, no han tomado en momentos de crisis nerviosas, de desarreglos emocionales, de intranquilidad y angustia, alguna de las tantas drogas que se conocen con el mote genérico de "ataráxicos", de "tranquilizantes". Pues bien, hablemos un poco sobre este tema, sus antecedentes históricos y filosóficos y lo que para los griegos clásicos significaba el vocablo "ataraxia".

  2. Reflexiones sobre el concepto de justicia

    Directory of Open Access Journals (Sweden)

    Víctor C. Pascual Planchuelo

    2005-06-01

    Full Text Available Este ensayo constituye una reflexión sobre el concepto de Justicia. No se centra, como tantos estudios al respecto, en el plano teórico y metafísico, sino que atiende problemas de mayor actualidad: la opinión de los ciudadanos, la postura de los profesionales y otros asuntos controvertidos del ámbito del Derecho.

  3. Monografía FOMIN sobre Remesas

    OpenAIRE

    Inter-American Development Bank; Analistas Financieros Internacionales (AFI)

    2009-01-01

    Consultoria realizada por Analistas Financieros Internacionales para Fondo Multilateral de Inversiones sobre: Flujos de remesas a América Latina: Características del mercado de remesas y sus actores principales. Aspectos regulatorios relevantes para facilitar el rol de las remesas como instrumento de desarrollo. Descripción de la cartera de proyectos FOMIN y su nueva estrategia en el Cluster de Remesas.

  4. Cumbre Mundial sobre Desarrollo Social. Copenhague

    OpenAIRE

    Abellán García, Antonio

    1995-01-01

    La Asamblea General de Naciones Unidas adoptó en 1992 la decisión De convocar una Cumbre Mundial sobre Desarrollo Social para afrontar los problemas de pobreza, desempleo e integración social. La Cumbre tuvo lugar en marzo de 1995, en Copenhague, y se desarrolló en tres partes: Plenario, Comité Principal y Cumbre de Jefes de Estado o Gobierno

  5. 罗格列酮上调成人隐匿性自身免疫糖尿病患者CD4+T细胞Foxp3 mRNA的表达%Rosiglitazone upregulates Foxp3 mRNA expression of CD4+T cells in adults with latent autoimmune diabetes

    Institute of Scientific and Technical Information of China (English)

    杨治芳; 周智广; 黄干; 彭健; 颜湘

    2008-01-01

    目的 观察罗格列酮对成人隐匿性自身免疫糖尿病(LADA)患者CD4+调节性T细胞的影响,旨在探讨罗格列酮的免疫调节机制.方法 采用磁珠分离LADA患者CD4+T细胞,1、10和100 μmol/L罗格列酮干预CIM+T细胞.MTT法检测细胞活性,3H-TdR掺人法检测增殖抑制率.流式细胞术检测CD4+CD25+T细胞比值.RT-PCR检测过氧化物酶体增殖激活受体-γ(PPARγ)mRNA、TGF-β1 mRNA表达,实时荧光定量PCR检测Foxp3 mRNA表达.结果 CD4+T细胞表达PPARγmRNA.罗格列酮抑制植物凝集素(PHA)刺激的CD4+T细胞增殖.1μmol/L和10μmol/L组罗格列酮作用的CD4+CD25+T细胞比例无明显变化,100 μmol/L组CD4+CD25+T细胞比例降低.10μmol/L罗格列酮上调CD4+T细胞的Foxp3 mRNA表达,但TGF-β1 mRNA表达无显著变化.小剂量IL-2参与下,1μmol/L罗格列酮(药理浓度范围内)升高CD4+T细胞Foxp3mRNA表达.结论 罗格列酮上调LADA患者CD4+T细胞Foxp3 mRNA表达,改善自身免疫耐受缺陷.%Objective To investigate the effect of rosiglitazone on the CD4+regulatory T cells in the patients with latent autoimmune diabetes in adults(LADA).Methods The CIM+T cells from IADA patients were isolated with anti-CD4-dynal magnetic beads.The expression of Foxp3 mRNA,along with peroxisome proliferators activator receptors gamma(PPARγ)mRNA and TGF-131 mRNA was determined.The effect of rosiglitazone on CD4+T cells was measured,after treated with rosiglitazone for 48 h.Cell viability was assessed by Mtit assay.The proliferation was assayed with 3 H-TdR.Two-color staining(anti-CD4,anti-CD25)flow cytometric analysis was employed to measure the percentage of CD4+CD25+T cells of Deriph eral blood.Resuits PPARγmRNA was expressed in peripheral CD4+T lymphocytes.RosiglitazoBe inhibited phytohemagglutinin(PHA)-induced human CD4+T cell proliferation in dose dependence.The percentage of CD4+CD25+T cells showed no significant change after the peripheral blood culture with 1 μmol/Land 10

  6. Influence of cadmium on Bcl-2, Bax and Caspase-3 mRNA transcription in rat's primary cultured cerebral cortical neurons%镉对大鼠大脑皮质神经细胞Bcl-2,Bax和Caspase-3mRNA转录的影响

    Institute of Scientific and Technical Information of China (English)

    袁燕; 孙娅; 江辰阳; 刘学忠; 顾建红; 卞建春; 刘宗平

    2012-01-01

    To investigate the effects of cadmium on transcription levels of apoptosis-related genes Bcl-2,Bax and Caspase-3 mRNA in primary cerebral cortical neurons of SD rats,the neurons were exposured to cadmium at different concentrations (0,5,10,20μmol/L ) for 12 h. MTT assay was applied to test the cell viability,and real-time fluorescent quantitative PCR was used to detect the transcription levels of Bcl-2,Bax and Caspase-3 mRNA. In comparison with the control group, the results showed that the cell viability decreased significantly with the higher concentration cadmium (P〈0.05 or P〈0.01). Additionally, transcription levels of Bax and Caspase-3 mRNA increased significantly (P〈0.01),but transcription level of Bcl-2 mRNA and Bcl-2/Bax decreased signifi- cantly (P〈0. 05,P〈0. 01). It was concluded that cadmium can inhibit the growth of neurons and regulate the transcription of apoptosis-related genes,including Bcl-2,Bax and Caspase-3.%为研究镉对大鼠大脑皮质神经细胞凋亡相关基因Bcl-2、Bax和Caspase-3mRNA转录水平的影响,选用不同浓度(0、5、10、20μmol/L)醋酸镉染毒大鼠大脑皮质神经细胞12h,用MTT法检测细胞存活率,实时荧光定量PCR检测Bcl-2、Bax和Caspase-3mRNA的转录水平,并计算Bcl-2/Bax的比值。结果表明,与对照组相比,各染毒组细胞存活率随染毒剂量增加而显著下降(P〈0.05或P〈0.01);Bax和Caspase-3mRNA转录水平极显著升高(P〈0.01),而Bcl-2mRNA转录水平显著降低(P〈0.05),Bcl-2/Bax极显著降低(P〈0.01)。说明镉能抑制大鼠大脑皮质神经细胞的生长,并可调节凋亡相关基因Bcl2、Bax和Caspase-3mRNA的转录。

  7. Packaging of the recombinant lentivirus delivering microRNA-383sequences and its positive effects on Foxp3 mRNA in human PBMCs%携带microRNA-383重组慢病毒的包装及其上调PBMCs中Foxp3mRNA的表达

    Institute of Scientific and Technical Information of China (English)

    周峰; 张庆; 张海清; 刘晓梅; 史震; 郑葵阳

    2011-01-01

    目的 包装携带microRNA-383(miR-383)的重组慢病毒,并观察其对正常人外周血单个核细胞(peripheral blood mononuclear ce11s,PBMCs)中Foxp3 mRNA转录的影响.方法 将4个串联的miRNA-383前体序列亚克隆人慢病毒转移载体pHAGE-CMV-MCS-IZsGreen,构建重组载体,命名为pHAGE-miR-383.将pHAGE-383、包装质粒psPAX2与包膜质粒pMD2.G共转染入HEK293T细胞进行重组慢病毒包装.进而分别采用定量PCR和RT-PCR检测慢病毒miR-383和Mock感染48 h后细胞中的miR-383的表达和转录因子Foxp3 mRNA的转录水平.结果 定量PCR证实携带miR-383的重组慢病毒包装成功,滴度为1×10(7)TU/ml.以MOI为5的慢病毒感染HEK293T细胞后miR-383表达明显增多.RT-PCR结果显示,miR-383能够上调PBMCs中Foxp3 mRNA的表达.结论 成功包装出含有miR-383前体序列的重组慢病毒,而且慢病毒miR-383能够上调PBMCs中Foxp3 mRNA的转录水平,为进一步研究其对调节性T细胞的调控作用奠定基础.%MicroRNAs (miRNAs)-mediated RNA interference is a vital regulatory pathway for many biological processes, such as development, differentiation, and homeostasis. As potent immune regulators, regulatory T cells (Tregs) are strictly regulated by Foxp3, a transcription factor. To produce the recombinant lentivirus containing pre-microRNA-383 (miR-383) sequences and to determinate the effect miR-383 on F0XP3 mRNA level in human peripheral blood mononuclear cells (PBMCs), four pre-miR-383 sequences in series were subcloned into the lentiviral transfected plasmid pHAGE-CMV-MCS-IZsGreen (named as pHAGE-miR-383). And then the pHAGE-miR-383, packaged plasmid psPAX2, and envelope plasmid pMD2.G were co-transfected into the HEK 293T cells with lipofectamine reagent. The viral titer was checked by observing the expression of green fluorescent protein (GFP). Moreover, real-time PCR assay was performed to measure miR-383 level and RT-PCR to test Foxp3 mRNA level in cells infected by lentiviral mi

  8. Topochemical fluorination of Sr3(M(0.5)Ru(0.5))2O7 (M = Ti, Mn, Fe), n = 2, Ruddlesden-Popper phases.

    Science.gov (United States)

    Romero, Fabio Denis; Bingham, Paul A; Forder, Susan D; Hayward, Michael A

    2013-03-18

    Reaction of the appropriate Sr3(M(0.5)Ru(0.5))2O7 (M = Ti, Mn, Fe), n = 2, Ruddlesden-Popper oxide with CuF2 under flowing oxygen results in formation of the oxide-fluoride phases Sr3(Ti(0.5)Ru(0.5))2O7F2, Sr3(Mn(0.5)Ru(0.5))2O7F2, and Sr3(Fe(0.5)Ru(0.5))2O(5.5)F(3.5) via a topochemical anion insertion/substitution process. Analysis indicates the titanium and manganese phases have Ti(4+), Ru(6+) and Mn(4+), Ru(6+) oxidation state combinations, respectively, while Mössbauer spectra indicate an Fe(3+), Ru(5.5+) combination for the iron phase. Thus, it can be seen that the soft fluorination conditions employed lead to formation of highly oxidized Ru(6+) centers in all three oxide-fluoride phases, while oxidation states of the other transition metal M cations remain unchanged. Fluorination of Sr3(Ti(0.5)Ru(0.5))2O7 to Sr3(Ti(0.5)Ru(0.5))2O7F2 leads to suppression of magnetic order as the fluorinated material approaches metallic behavior. In contrast, fluorination of Sr3(Mn(0.5)Ru(0.5))2O7 and Sr3(Fe(0.5)Ru(0.5))2O7 lifts the magnetic frustration present in the oxide phases, resulting in observation of long-range antiferromagnetic order at low temperature in Sr3(Mn(0.5)Ru(0.5))2O7F2 and Sr3(Fe(0.5)Ru(0.5))2O(5.5)F(3.5). The influence of the topochemical fluorination on the magnetic behavior of the Sr3(M(0.5)Ru(0.5))2O(x)F(y) phases is discussed on the basis of changes to the ruthenium oxidation state and structural distortions.

  9. Luminescence properties of Na{sub 3}YSi{sub 3}O{sub 9}:M{sup 3+} (M = Sm, Tb, Tm) glass ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Wenyu, E-mail: zhaowenyu2011@hotmail.com [School of Chemistry and Chemical Engineering, Inner Mongolia University of Science and Technology, Baotou 014010 (China); School of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing 100083 (China); An, Shengli [School of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing 100083 (China); School of Material and Metallurgical Engineering, Inner Mongolia University of Science and Technology, Baotou 014010 (China); Fan, Bin; Li, Songbo [School of Chemistry and Chemical Engineering, Inner Mongolia University of Science and Technology, Baotou 014010 (China)

    2013-07-25

    Highlights: •Sm{sup 3+}, Tb{sup 3+}, or Tm{sup 3+} doped-Na{sub 3}YSi{sub 3}O{sub 9} GC emit reddish, green, or blue light, respectively. •Emission intensities of these glass ceramics are superior to corresponding phosphors. •Color tones of Na{sub 3}YSi{sub 3}O{sub 9}:Sm{sup 3+}, Tb{sup 3+}, Tm{sup 3+} GC can be changed from warm white to cool white. •These glass ceramics have potential application in white LED devices. -- Abstract: The transparent Na{sub 3}YSi{sub 3}O{sub 9}:M{sup 3+} (M = Sm, Tb, Tm) glass ceramics were prepared by high temperature melting with a heat-treatment at 750 °C. X-ray diffraction, transmission electron microscopy, and photoluminescence spectroscopy were used to investigate their structure and optical properties. The M{sup 3+} ions were introduced as luminescence centers into the Na{sub 3}YSi{sub 3}O{sub 9} glass ceramics. Under ultraviolet (UV) excitation, the Na{sub 3}YSi{sub 3}O{sub 9}:Sm{sup 3+}, Na{sub 3}YSi{sub 3}O{sub 9}:Tb{sup 3+}, and Na{sub 3}YSi{sub 3}O{sub 9}:Tm{sup 3+} glass ceramics exhibited the characteristic transitions of Sm{sup 3+} ({sup 4}G{sub 5/2} → {sup 6}H{sub J}, J = 5/2 and 7/2), Tb{sup 3+} ({sup 5}D{sub 4} → {sup 7}F{sub J}, J = 6, 5 and 4), and Tm{sup 3+} ({sup 1}D{sub 2} → {sup 3}F{sub 4}), respectively. The color tones of Na{sub 3}YSi{sub 3}O{sub 9}:Sm{sup 3+}, Tb{sup 3+}, Tm{sup 3+} glass ceramic changed from cool white (0.2589, 0.3119) to warm white (0.3231, 0.4491) by adjusting the excitation wavelength. The results indicated that the Na{sub 3}YSi{sub 3}O{sub 9}:M{sup 3+} (M = Sm, Tb, Tm) glass ceramic is a potential matrix material for white light-emitting diodes (LEDs) under UV-LED excitation.

  10. Control technology assessment of hazardous waste disposal operations in chemicals manufacturing: at 3M Company Chemolite incinerator, Cottage Grove, Minnesota, indepth survey report

    Energy Technology Data Exchange (ETDEWEB)

    Anastas, M.

    1984-01-01

    Environmental and breathing zone samples were analyzed for organic solvents and total hydrocarbons at the Chemolite incinerator at 3M Company (SIC-2800), Cottage Grove, Minnesota in September 1982. Engineering controls in the pump room and on the drum feed system were investigated. Concentrations of all solvents and total hydrocarbons were below all relevant standards or the limits of detection. General and local exhaust ventilation were used to suppress air contaminant concentrations in the pump room. The ventilation system supplied fresh air at the rate of 15 room changes per hour. General dilution ventilation was the primary control on the drum feed system. A carbon-dioxide injection system and overhead vent were used to minimize potential fire and explosion hazards. Grounding devices were installed on liquid waste feed lines to prevent the occurrence of sparks caused by flowing liquids. Hard hats, safety glasses, company provided uniforms, and safety shoes were routinely worn at the incineration site. Rubber suits, face shields, and half face respirators were worn when corrosive materials were handled. The company had intensive training and education programs. Only minor injuries occurred during the 11 year history of the facility.

  11. The influence of plasma horizontal position on the neutron rate and flux of neutral atoms in injection heating experiment on the TUMAN-3M tokamak

    Science.gov (United States)

    Kornev, V. A.; Chernyshev, F. V.; Melnik, A. D.; Askinazi, L. G.; Wagner, F.; Vildjunas, M. I.; Zhubr, N. A.; Krikunov, S. V.; Lebedev, S. V.; Razumenko, D. V.; Tukachinsky, A. S.

    2013-11-01

    Horizontal displacement of plasma along the major radius has been found to significantly influence the fluxes of 2.45 MeV DD neutrons and high-energy charge-exchange atoms from neutral beam injection (NBI) heated plasma of the TUMAN-3M tokamak. An inward shift by Δ R = 1 cm causes 1.2-fold increase in the neutron flux and 1.9-fold increase in the charge-exchange atom flux. The observed increase in the neutron flux is attributed to joint action of several factors-in particular, improved high-energy ion capture and confinement and, probably, decreased impurity inflow from the walls, which leads to an increase in the density of target ions. A considerable increase in the flux of charge-exchange neutrals in inward-shifted plasma is due to the increased number of captured high-energy ions and, to some extent, the increased density of the neutral target. As a result of the increase in the content of high-energy ions, the central ion temperature T i (0) increased from 250 to 350 eV. The dependence of the neutron rate on major radius R 0 should be taken into account when designing compact tokamak-based neutron sources.

  12. Dependence of electrical transport properties of CaO(CaMnO3)m (m = 1, 2, 3, ∞) thermoelectric oxides on lattice periodicity

    Science.gov (United States)

    Baranovskiy, Andrei; Amouyal, Yaron

    2017-02-01

    The electrical transport properties of CaO(CaMnO3)m (m = 1, 2, 3, ∞) compounds are studied applying the density functional theory (DFT) in terms of band structure at the vicinity of the Fermi level (EF). It is shown that the total density of states (DOS) values at EF increase with increase in the m-values, which implies an increase in the electrical conductivity, σ, with increasing m-values, in full accordance with experimental results. Additionally, the calculated values of the relative slopes of the DOS at EF correlate with the experimentally measured Seebeck coefficients. The electrical conductivity and Seebeck coefficients were calculated in the framework of the Boltzmann transport theory applying the constant relaxation time approximation. By the analysis of experimental and calculated σ(Τ) dependences, the electronic relaxation time and mean free path values were estimated. It is shown that the electrical transport is dominated by electron scattering on the boundaries between perovskite (CaMnO3) and Ca oxide (CaO) layers inside the crystal lattice.

  13. [Effect of Zhuangyao Jianshen Wan (ZYJCW) on P2X1 and P2X3 mRNA expressions in rats with diuresis caused by kidney deficiency].

    Science.gov (United States)

    Chen, Jia-yi; Jiang, Wei-wen; He, Feng-lei; Mo, Guo-qiang; Guo, Zhong-hui; Wang, Xiao-dan; Wu, Qing-he; Cao, Hong-yin

    2015-08-01

    To investigate the urination-reducing effect and mechanism of Zhuangyao Jianshen Wan (ZYJCW). In this study, SI rats were subcutaneously injected with 150 mg · kg(-1) dose of D-galactose to prepare the sub-acute aging model and randomly divided into the model group, the Suoquan Wan group (1.17 g · kg(-1) · d(-1)), and ZYJCW high, medium and low dose groups (2.39, 1.20, 0.60 g · kg(-1) · d(-1)) , with normal rats in the blank group. They were continuously administered with drugs for eight weeks. The metabolic cage method was adopted to measure the 24 h urine volume and 5 h water load urine volume in rats. The automatic biochemistry analyzer was adopted to detect urine concentrations of Na+, Cl-, K+. The ELISA method was used to determine serum aldosterone (ALD) and antidiuretic hormone (ADH). The changes in P2X1 and P2X3 mRNA expressions in bladder tissues of rats were detected by RT-PCR. According to the results, both ZYJCW high and medium dose groups showed significant down-regulations in 24 h urine volume and 5 h water load urine volume in (P diuresis caused by kidney deficiency.

  14. Theoretical and experimental studies of formation and migration of oxygen vacancies in BaM x Ti1- x O3 (M = Zr, Ge)

    Science.gov (United States)

    Umeda, Yuji; Aman, Sanshiro; Kuwabara, Akihide; Moriwake, Hiroki

    2016-10-01

    The formation and migration energies of oxygen vacancies in pure BaTiO3, and BaM x Ti1- x O3 (M = Zr, Ge) are calculated by first-principles calculations to understand the effect of doping on the reliability of multilayer ceramic capacitors (MLCCs). The formation and migration energies of oxygen vacancies are found to be larger in BaZr x Ti1- x O3 than in BaTiO3. This finding could be one of the possible reasons behind the improved reliability of Zr-doped MLCCs materials. On the other hand, by substituting Ge, the migration energy of BaGe x Ti1- x O3 becomes larger than that of BaTiO3. This is despite the smaller oxygen vacancy formation energy in BaGe x Ti1- x O3 than in BaTiO3. Even though Zr and Ge are tetravalent in BaM x Ti1- x O3, their valence states are different after the formation of oxygen vacancies, providing an explanation for the differences in vacancy formation and migration energies between BaZr x Ti1- x O3 and BaGe x Ti1- x O3. Our theoretical results are further confirmed by experiments on these model systems.

  15. Strain-dependent ferroic properties of doped LaMO{sub 3}(M=Mn or Co) and BiFeO{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, Kathrin; Rata, Diana; Herklotz, Andreas; Bilani, Orkidia; Dekker, Martina; Schultz, Ludwig [IFW Dresden, Postfach 270116, 01171 Dresden (Germany); Reibold, Marianne [Technische Universitaet Dresden, Speziallabor Triebenberg, 01328 Dresden (Germany); Biegalski, Michael; Christen, Hans [Oak Ridge National Laboratory, CNMS, PO Box 2008, Bethel Valley Rd., Oak Ridge, TN 37831 (United States)

    2010-07-01

    Elastic strain at epitaxially grown interfaces provides an efficient coupling mechanism in two-phase multiferroics: piezoelectric or magnetostrictive strain arising from application of an electric or a magnetic field is transferred readily between the components. We employ a piezoelectric single-crystalline substrate to apply reversible biaxial strain to epitaxially grown magnetic or ferroelectric films and study the strain response of their ferroic properties. The relaxor-based 0.72PbMg{sub 1/3}Nb{sub 2/3}O{sub 3} -0.28PbTiO{sub 3}(001) (PMN-PT) proved to be a favourable piezo-substrate with large, reversible, uniform in-plane strain which shows little temperature dependence. The magnetization vs. strain of doped LaMO{sub 3} (M=Mn or Co) phases has been studied. It reveals the impact of the strain-induced tetragonal lattice distortion on the ferromagnetic double exchange and the magnetic moment of Co ions that leads to moderate or large magnetization modulation. Further, the strain dependence of ferroelectric switching has been investigated for multiferroic BiFeO{sub 3}. It displays a large response of unexpected sign attributed to a strain influence on kinetics.

  16. Frustrated spin-1/2 molecular magnetism in the mixed-valence antiferromagnets Ba3M Ru2O9 (M =In , Y, Lu)

    Science.gov (United States)

    Ziat, D.; Aczel, A. A.; Sinclair, R.; Chen, Q.; Zhou, H. D.; Williams, T. J.; Stone, M. B.; Verrier, A.; Quilliam, J. A.

    2017-05-01

    We have performed magnetic susceptibility, heat capacity, muon spin relaxation, and neutron-scattering measurements on three members of the family Ba3M Ru2O9 , where M =In , Y, and Lu. These systems consist of mixed-valence Ru dimers on a triangular lattice with antiferromagnetic interdimer exchange. Although previous work has argued that charge order within the dimers or intradimer double exchange plays an important role in determining the magnetic properties, our results suggest that the dimers are better described as molecular units due to significant orbital hybridization, resulting in one spin-1/2 moment distributed equally over the two Ru sites. These molecular building blocks form a frustrated, quasi-two-dimensional triangular lattice. Our zero- and longitudinal-field μ SR results indicate that the molecular moments develop a collective, static magnetic ground state, with oscillations of the zero-field muon spin polarization indicative of long-range magnetic order in the Lu sample. The static magnetism is much more disordered in the Y and In samples, but they do not appear to be conventional spin glasses.

  17. A Theoretical Investigation on CO Oxidation by Single-Atom Catalysts M1/γ-Al2O3 (M=Pd, Fe, Co, and Ni).

    Science.gov (United States)

    Yang, Tao; Fukuda, Ryoichi; Hosokawa, Saburo; Tanaka, Tsunehiro; Sakaki, Shigeyoshi; Ehara, Masahiro

    2017-04-07

    Single-atom catalysts have attracted much interest recently because of their excellent stability, high catalytic activity, and remarkable atom efficiency. Inspired by the recent experimental discovery of a highly efficient single-atom catalyst Pd1/γ-Al2O3, we conducted a comprehensive DFT study on geometries, stabilities and CO oxidation catalytic activities of M1/γ-Al2O3 (M=Pd, Fe, Co, and Ni) by using slab-model. One of the most important results here is that Ni1/Al2O3 catalyst exhibits higher activity in CO oxidation than Pd1/Al2O3. The CO oxidation occurs through the Mars van Krevelen mechanism, the rate-determining step of which is the generation of CO2 from CO through abstraction of surface oxygen. The projected density of states (PDOS) of 2p orbitals of the surface O, the structure of CO-adsorbed surface, charge polarization of CO and charge transfer from CO to surface are important factors for these catalysts. Although the binding energies of Fe and Co with Al2O3 are very large, those of Pd and Ni are small, indicating that the neighboring O atom is not strongly bound to Pd and Ni, which leads to an enhancement of the reactivity of the O atom toward CO. The metal oxidation state is suggested to be one of the crucial factors for the observed catalytic activity.

  18. Blazar variability studies with the 1.3m Robotically Controlled Telescope and the automated 0.6m Bell Observatory telescope

    Science.gov (United States)

    Carini, M. T.; Barnaby, D.; Mattox, J. R.; Walters, R.; Poteet, C.; Wills, W.; Gelderman, R.; Davis, D.; Everett, M.; Guinan, E.; Howell, S.; McGruder, C. H., III

    2004-10-01

    One of the key programs on the 1.3m Robotically Controlled Telescope (RCT) located at Kitt Peak National Observatory and the 0.6m telescope at the Bell Observatory operated by Western Kentucky University is a study of the variability of the class of Active Galactic Nuclei (AGN) known as Blazars. Blazars are highly variable on timescales of minutes to decades and this variability is seen across the electromagnetic spectrum. In addition, they display a featureless spectrum, thus continuum variability provides the only diagnostic of these objects. Variability provides information on the size of the emission region responsible for the observed variations and when observations are obtained at multiple wavelengths, it can be used to discriminate between emission models. However, traditional ground based observations are limited in a variety of ways. We will discuss how an automated facility, with time dedicated to this astrophysically interesting problem, can overcome many of these limitations, and we show results from the Bell Observatory as well as some of the first results of Blazar observations from the RCT.

  19. Competition between Alkalide Characteristics and Nonlinear Optical Properties in OLi3-M-Li3O (M=Li, Na and K) Complexes

    CERN Document Server

    Srivastava, Ambrish Kumar

    2016-01-01

    Alkalides possess enhanced nonlinear optical (NLO) responses due to localization of excess electrons on alkali metals. We have proposed a new class of alkalides by sandwiching alkali atoms (M) between two Li3O superalkali clusters at MP2/6-311++G(d,p) level. We notice a competition between alkalide characteristics and NLO properties in OLi3-M-Li3O (M=Li, Na and K) isomers. For instance, the atomic charge on M (qM) in D2h structure is -0.58e for M=Li and its first static mean hyperpolarizablity (\\b{eta}o) is 1 a.u., but in C2v structure, qM=-0.12e and \\b{eta}o= 3.4*103 a.u. More interestingly, the \\b{eta}o value for M=K (C2v) increases to 1.9*104 a.u. in which qM=0.24e. These findings may provide new insights into the design of alkalides, an unusual class of salts and consequently, lead to further researches in this direction.

  20. Curcumin as the OO bidentate ligand in "2 + 1" complexes with the [M(CO)3]+ (M = Re, 99mTc) tricarbonyl core for radiodiagnostic applications.

    Science.gov (United States)

    Sagnou, Marina; Benaki, Dimitra; Triantis, Charalampos; Tsotakos, Theodoros; Psycharis, Vassilis; Raptopoulou, Catherine P; Pirmettis, Ioannis; Papadopoulos, Minas; Pelecanou, Maria

    2011-02-21

    The synthesis and characterization of "2 + 1" complexes of the [M(CO)(3)](+) (M = Re, (99m)Tc) core with the β-diketones acetylacetone (complexes 2, 8) and curcumin (complexes 5, 10 and 6, 11) as bidentate OO ligands, and imidazole or isocyanocyclohexane as monodentate ligands is reported. The complexes were synthesized by reacting the [NEt(4)](2)[Re(CO)(3)Br(3)] precursor with the β-diketone to generate the intermediate aqua complex fac-Re(CO)(3)(OO)(H(2)O) that was isolated and characterized, followed by replacement of the labile water by the monodentate ligand. All complexes were characterized by mass spectrometry, NMR and IR spectroscopies, and elemental analysis. In the case of complex 2, bearing imidazole as the monodentate ligand, X-ray analysis was possible. The chemistry was successfully transferred at (99m)Tc tracer level. The curcumin complexes 5 and 6, as well as their intermediate aqua complex 4, that bear potential for radiopharmaceutical applications due to the wide spectrum of pharmacological activity of curcumin, were successfully tested for selective staining of β-amyloid plaques of Alzheimer's disease. The fact that the complexes maintain the affinity of the mother compound curcumin for β-amyloid plaques prompts for further exploration of their chemistry and biological properties as radioimaging probes.

  1. Influence of functionalized pyridine ligands on the radio/chemical behavior of [M(I)(CO)3](+) (M = Re and (99m)Tc) 2 + 1 complexes.

    Science.gov (United States)

    Hayes, Thomas R; Lyon, Patrice A; Barnes, Charles L; Trabue, Steven; Benny, Paul D

    2015-02-16

    While a number of chelate strategies have been developed for the organometallic precursor fac-[M(I)(OH2)3(CO)3](+) (M = Re, (99m)Tc), a unique challenge has been to improve the overall function and performance of these complexes for in vivo and in vitro applications. Since its discovery, fac-[M(I)(OH2)3(CO)3](+) has served as an essential scaffold for the development of new targeted (99m)Tc based radiopharmaceuticals due to its labile aquo ligands. However, the lipophilic nature of the fac-[M(I)(CO)3](+) core can influence the in vivo pharmacokinetics and biodistribution of the complexes. In an effort to understand and improve this behavior, monosubstituted pyridine ligands were used to assess the impact of donor nitrogen basicity on binding strength and stability of fac-[M(I)(CO)3](+) in a 2 + 1 labeling strategy. A series of Re and (99m)Tc complexes were synthesized with picolinic acid as a bidentate ligand and 4-substituted pyridine ligands. These complexes were designed to probe the effect of pKa from the monodentate pyridine ligand both at the macro scale and radiochemical concentrations. Comparison of X-ray structural data and radiochemical solution experiments clearly indicate an increase in overall yield and stability as pyridine basicity increased.

  2. Effect of sirolimus on the expression of integrin ανβ3 mRNA in cardiac allograft in rats%西罗莫司对大鼠移植心脏组织中整合素ανβ3mRNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    胡名松; 胡建国; 郑宝石

    2011-01-01

    Objective To investigate the effect of sirolimus (SRL) on the expression of integrin ανβ3 mRNA in vascular smooth muscle cells of cardiac allografts in rats, and the possible mechanism of SRL in the prevention of cardiac allograft vasculopathy. Methods Heterotopic heart transplantation models were established. Hearts from Wistar rats were heterotopically transplanted to SD rats (allograft) or Wistar rats (isograft). All rats were randomly divided into four groups:SRL group, SRL 1.25 mg/kg every day,oral intubation after cardiac transplantation; cyclosporine (CsA) group,CsA 10mg/kg every day, subcutaneous administration ; isograft group, no immunosuppressant administration;control group, normal hearts of Wistar rats. All of the animals were killed at 60 day after transplantation. Angiostenosis degree was analyzed by Mias system 4.1 after the cardiac tissues were stained with Van Gieson stain. Reverse transcription-polymerase chain reaction (RT-PCR) assay was used to detect the expression of integrin ανβ3 mRNA in cardiac allografts. The relationship between the expression of integrin ανβ3 mRNA and the area of vascular stenosis was analyzed. ResultsIn control group, there was no thickened vascular intima and no vascular stenosis. In allograft group,the thickness of vascular intima was slightly increased but no vascular stenosis was detected. In CsA group, the vascular intima was obviously thickened, the lumen was narrowed, and some small arteries had obstruction. In SRL group, vascular intima proliferation and angiostenosis degree were obviously milder than in CsA group. Semiquantitative RT-PCR analysis revealed that the relative expression of integrin ανβ3 mRNA in CsA and SRL groups was increased significantly as compared with control group and isograft group (2.51±0.43 or 1.17±0.12 vs 0.28±0.08 or 0. 38 ± 0. 05, P<0. 01). The relative expression of integrin ανβ3 mRNA in SRL group was decreased significantly as compared with CsA group (1.17±0

  3. ESTUDO SOBRE O IMPACTO DOS PROCESSADORES HOSPEDEIROS

    Directory of Open Access Journals (Sweden)

    Alba S. B. Lopes

    2008-05-01

    Full Text Available Arquiteturas reconfiguráveis são dispositivos de hardware capazes de modificar sua estrutura de hardware de acordo com a aplicação a ser executada. Tais dispositivos surgiram como uma alternativa às soluções de hardware tradicionais na tentativa de equilibrar flexibilidade e desempenho. Uma das principais formas de utilização de arquiteturas reconfiguráveis corresponde a um bloco reconfigurável anexado a um processador hospedeiro. Esse processador é responsável por executar diversas tarefas críticas, incluindo o particionamento hardware/software e indicar o momento do bloco reconfigurável executar. Apesar de existirem diversas propostas de arquiteturas reconfiguráveis na literatura, pouco se estudou sobre o impacto do processador hospedeiro na arquitetura. Nesse contexto, esse artigo apresenta um estudo sobre o impacto do processador hospedeiro no desempenho da arquitetura reconfigurável híbrida. Como estudo de caso foi realizada uma avaliação sobre o uso dos processadores SPARC V8 da Sun Microsystems e Nios II da Altera como processadores hospedeiros da arquitetura reconfigurável híbrida RoSA. O objetivo deste estudo é realizar a comparação entre o desempenho desses processadores e identificar qual deles é o mais adequado para anexar a arquitetura em questão. Os resultados mostraram que foi possível alcançar até 47% de ganho de desempenho com o uso do processador Nios II em comparação ao SPARC V8, indicando o primeiro como mais adequado para a arquitetura RoSA. PALAVRAS-CHAVE: arquiteturas reconfiguráveis, processador hospedeiro, desempenho.

  4. 3M Filtek Z350流动树脂与Pekaseal光固化窝沟封闭剂预防儿童龋病的临床效果研究%Comparison of Preventive Effect of 3M Filtek Z350 Flowable Resin and Pekaseal Light-Cured Sealant for Caries in Children

    Institute of Scientific and Technical Information of China (English)

    蒲寒秋; 肖世芳; 勾京东

    2013-01-01

      目的对比观察3M Filtek Z350流动复合树脂与Pekaseal光固化窝沟封闭剂预防儿童恒磨牙龋病的临床效果。方法对2009年1月至2011年6月间本院门诊符合纳入标准的126名6~10岁儿童的315颗恒磨牙随机分为两组,观察组选择3M Filtek Z350流动复合树脂进行窝沟封闭治疗(病例数=63,牙数=136),对照组采用Pekaseal光固化窝沟封闭剂进行窝沟封闭治疗(病例数=63,牙数=179),随访6个月~1年,复查封闭剂保留情况和患龋情况。结果术后6个月观察组和对照组窝沟封闭剂保留率无统计学差异(P>0.05),术后1年观察组封闭剂保留率高于对照组,差异有统计学意义(P<0.05)。术后6个月、1年,观察组患龋率均低于对照组,差异均有统计学意义(P<0.05)。结论采用3M Filtek Z350流动复合树脂进行窝沟封闭预防儿童恒磨牙窝沟龋效果显著,使龋病发生率大大降低,优于传统的窝沟封闭剂,值得临床推广应用。%Objective To compare the preventive effect of 3M Filtek Z350 flowable resin and Pekaseal light-cured pit and fissure sealant for caries in children. Methods One hundred and twenty six children aged 6 to 10 years were selected to perform sealant technique on their first permanent molars. First molars in trial group were sealed with 3M Filtek Z350 flowable resin and in control group were sealed with Pekaseal light-cured sealant. Sealant retention rate and caries prevalence were observed during 1-year follow up. Rusults At 6-month follow up, there were no statistical difference in sealant retention rate between the two groups(P>0.05). At 1 year follow up, the retention rate of flowable resin group was significantly higher than that of light-cured sealant group(P<0.05). However,caries prevalence of flowable resin group was significantly lower than that of light-cured sealant group at both 6-month and 1-year follow up(P<0.05).Conclusion 3M Filtek Z350 flowable

  5. Literatura infantil sobre problemas infantiles: la diabetes

    OpenAIRE

    Lázaro Fernández, Patricia

    2015-01-01

    Debido al creciente número de casos de diabetes infantil que se está dando en la sociedad actual, no es raro encontrarse en las aulas cada vez más casos de esta enfermedad. Por esta razón, he decidido analizar dos libros sobre esta temática, para hacer un acercamiento del material seleccionado a las aulas y poder desarrollar junto con los niños un aprendizaje colectivo y cooperativo. En este trabajo se expone la importancia de la literatura y la literatura infantil como una ...

  6. Algunas consideraciones sobre la arquitectura maya

    OpenAIRE

    Cejudo Collera, Mónica; DEPFA UNAM

    2013-01-01

    Con la finalidad de definir las variantes regionales y estilísticas que utilizaron los cons- tructores de la sociedad maya a lo largo de las varias etapas de su desarrollo, se estu- dian, en este artículo, los elementos que conforman las estructuras de la arquitectura maya. El resultado de este proceso de análisis permite ver cómo, a partir de una con- cepción global de la arquitectura y el urbanismo mayas, cada sitio se desarrolló sobre la base de su singularidad.

  7. Apuntes Sobre el Cultivo del Cacao.

    Directory of Open Access Journals (Sweden)

    Ochoa Horacio Ochoa

    1940-12-01

    Full Text Available En el presente artículo se hablara del proceso de fermentación del cacao, pero antes de entrar a detallar este proceso, es conveniente dar algunas anotaciones sobre los sistemas de recolección o “cosecha” empleados en distintos lugares, pues ellos tienen sus diferencias y en ocasiones no se efectúan con todo el cuidado necesario tanto para el árbol como para el producto que irá a los depósitos de fermentación.

  8. Soportes apoyados sobre vigas pretensadas (EE. UU.

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1965-12-01

    Full Text Available This work has been awarded a prize by the Prestreesed Concrete Institute. It refers to a number of flyovers on the Arroyo Seco, of California. This river has been canalized, to help drainage in case of heavy rainfall. The canal runs through a highly populated zone, and a motor road and accessory ramps had to cross the canal. The resulting design involves three prestressed girders, lightly arched in a parabolic outline, resting on each river shore, running along the line of the bridge, over the canal. It was decided that the bridge piles should not rest on the river bed, in order not to reduce its flow capacity. The girders of a maximum length of 39 ms, are box shaped, and stiffened with thin diaphragms. The cylindrical pile, 1.50 m in diameter, is an integral part of the girder, and applies to it a concentrated load of about 4000 tons. The girders rest on reinforced concrete cubes, which in turn are supported by concrete slabs and piles driven into the soil.Esta obra ha sido premiada por el Prestressed Concrete Institute y se refiere a una serie de pasos superiores sobre el Arroyo Seco, en California, que se ha canalizado para servir de desagüe en el caso de avenidas torrenciales. El canal se halla en una zona de edificación densa y se trata del paso—sobre aquél—de una autopista y rampas de acceso. La solución adoptada consistió en tres vigas pretensadas, ligeramente arqueadas con perfil parabólico, apoyadas en las dos márgenes y situadas en correspondencia con los tres soportes, sobre el propio canal, ya que ninguno de aquéllos debía apoyarse en el lecho de este último al objeto de no disminuir su capacidad de desagüe. Las vigas—de unos 39 m de longitud la mayor—son del tipo cajón, rigidizadas con unos diafragmas de pequeño espesor. El soporte cilíndrico, de 1,50 m de diámetro, se solidariza con la viga y le transmite una notable carga concentrada, del orden de 4.000 toneladas. Los apoyos de estas vigas son simples dados

  9. Novos conhecimentos sobre a flora bacteriana vaginal

    OpenAIRE

    Iara Moreno Linhares; Paulo Cesar Giraldo; Edmund Chada Baracat

    2010-01-01

    O objetivo desta revisão foi apresentar os novos conhecimentos sobre o ecossistema vaginal, enfatizando os métodos não cultiváveis de identificação microbiana (amplificação de genes), as várias espécies de Lactobacillus que podem compor a flora vaginal e a interação desta com os mecanismos locais de imunidade inata e adquirida, dependentes dos constituintes genéticos. Foram pesquisados no Medline (Pubmed) os artigos relacionados ao tema publicados entre 1997 e 2009, selecionando-se apenas os ...

  10. Modelos mentales sobre el concepto de medida

    OpenAIRE

    Osorio, Andrea Milena

    2009-01-01

    Esta tesis de maestría presenta los resultados de una investigación que tuvo como pretensión comprender la estructura de los modelos mentales sobre el concepto de medida que poseen estudiantes de segundo grado de la educación básica y los estudiantes de formación complementaria (estudiantes que inician la formación docente). Para recoger la información, se emplearon técnicas de recolección de información, la observación y la entrevista semiestructurada, que fueron aplicadas a 8 estudiant...

  11. Modelos mentales sobre el concepto de medida

    OpenAIRE

    Osorio, Andrea Milena; García, Ligia Inés

    2011-01-01

    El objetivo de esta investigación ha sido comprender la estructura de los modelos mentales sobre el concepto de medida que caracteriza a un grupo de estudiantes de segundo grado de básica primaria y de primer año de formación complementaria. En efecto, el interés es identificar los elementos que se dan en los modelos y analizar las posibles relaciones entre dichos elementos. El informe de investigación se encuentra presentado en 7 apartes. La primera parte comprendida por los numerales ...

  12. Comentarios sobre dibujo analítico

    OpenAIRE

    Mata Botella, Elena

    2004-01-01

    Cuaderno de apoyo a la docencia del DIBUJO DE ARQUITECTURA que pretende hacer reflexionar al alumno (de primero o segundo de carrera) sobre un tipo de dibujo que aquí se ha llamado “dibujo analítico”. Un dibujo que a través de operaciones gráficas y conceptuales como la esquematización y la selección de información, tiende a alejarse de la descripción del objeto arquitectónico para adentrarse en determinados aspectos o dimensiones que subyacen en el proyecto arquitectónico. Unas notas intr...

  13. Ensayo sobre la melancolía

    Directory of Open Access Journals (Sweden)

    Marta Chacón Salinas

    2013-07-01

    Full Text Available Este trabajo es un intento de delimitar la melancolía del conjunto de los trastornos depresivos y de reflexionar sobre sus características tal como aparecen en el discurso de los melancólicos. Se consideran algunas hipótesis en la línea psicoanalítica freudiana y lacaniana (Lambottc, Kristeva para entender cómo se va constituyendo en sus características principales: la intolerancia a la pérdida del objeto y el desfallecimiento del símbolo que le impide elaborar este duelo.

  14. Perspectivas sobre la comunicación

    OpenAIRE

    Naranjo Pereira, María Luisa

    2011-01-01

    Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la ...

  15. Consideraciones sobre de la ética

    OpenAIRE

    Enrique Cantolla Bernal

    2005-01-01

    El presente ensayo muestra como el hombre, a través de la historia, a estado constantemente buscando beneficios para su vida y ha debido cumplir con varias tareas, que con el tiempo han dado origen a costumbres y comportamientos que han llevado a constituir la moral y la ética. Esta última, nos permite definir y determinar los principales fines de la vida del hombre y cuales son los principios y normas que lo rigen. Así, el estudio de la ética nos plantea la interrogante sobre "los fines de l...

  16. Comentarios sobre dibujo analítico

    OpenAIRE

    Mata Botella, Elena

    2004-01-01

    Cuaderno de apoyo a la docencia del DIBUJO DE ARQUITECTURA que pretende hacer reflexionar al alumno (de primero o segundo de carrera) sobre un tipo de dibujo que aquí se ha llamado “dibujo analítico”. Un dibujo que a través de operaciones gráficas y conceptuales como la esquematización y la selección de información, tiende a alejarse de la descripción del objeto arquitectónico para adentrarse en determinados aspectos o dimensiones que subyacen en el proyecto arquitectónico. Unas notas intr...

  17. Nuevas tecnologias: sobre computadores y brujas

    OpenAIRE

    Buenaventura, Juan Guillermo

    1987-01-01

    No soy ingeniero, ni experto en nuevas tecnologías. Cualquier comentario que haga no puede ser más que o bien el comentario de un ciudadano preocupado por su país o bien el acercamiento personal al tema, por parte de un comunicador interesado en los impactos y potencialidades, que tienen estas tecnologías en el ejercicio profesional y en nuestra cultura. A mi modo de ver la literatura conocida sobre las nuevas tecnologías oscila entre dos polos, dentro de los cuales se encuentran los diferent...

  18. Apuntes sobre el cultivo del cacao

    OpenAIRE

    Chavarriaga, Eduardo; Ochoa, Horacio

    2013-01-01

    El sombrío constituye uno de los problemas que se presentan en el cultivo del cacao, de necesaria resolución para ayuda del agricultor en su labor al producir tan importante grano. Contribuye a la economía del cultivo un conocimiento amplio de la cuestión que debe preocupar al productor inquiriendo no solamente por lo acostumbrado en la región, sino por lo que en otras partes se conoce sobre el particular, para abandonar un poco el emperismo y hacer una industria cada día más próspera. Co...

  19. Sobre Wittgenstein y la ética

    OpenAIRE

    García Soto, Luis

    2010-01-01

    El objeto de este trabajo es analizar y discutir la visión que de la ética da Wittgenstein en su “Conferencia sobre Ética” (1930). En nuestra opinión, la visión de la ética dada por el filósofo está más próxima de la religión o de la literatura que de otros sistemas normativos, como el derecho, la política e incluso la economía. De acuerdo con esto, intentamos ofrecer otra visión de la ética.

  20. Perspectivas sobre la comunicación

    OpenAIRE

    Naranjo Pereira, María Luisa

    2005-01-01

    Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la ...

  1. Mas sobre coplas anónimas

    Directory of Open Access Journals (Sweden)

    Carlos López Narvaez

    1968-04-01

    Full Text Available Los estudiosos de la sabiduría popular colombiana, o folcloristas vocablo ya con ciudadanía académica- diéronse un tiempo a sostener, con argumentos copiosos, una polémica, sobre los orígenes ciertos de coplas, mitos, leyendas, costumbres, etc.; cuando estas modalidades "demosóficas"-(pidió llamarlas a sí un alto historiador y lingüista - se dan como yerbabuena en solar.

  2. Conceptos fundamentales sobre el mantenimiento de edificios

    OpenAIRE

    Juan Miguel Arencibia Fernández

    2007-01-01

    En esta investigación se realiza una profunda búsqueda sobre el tema del Mantenimiento de Edificios donde se abundan diferentes conceptos y criterios de la misma, encontrándose de esta forma los más utilizados métodos a emplear. Luego teniendo en cuenta las clasificación del Mantenimiento de Edificio según los tipos de obras, propietarios del inmueble y el momento que éste se realiza, como los costos de una edificación y su equipamiento a utilizar. Otros de los aspectos a tener en cuenta es l...

  3. Debate sobre el agua : punto de partida

    OpenAIRE

    2013-01-01

    A lo largo de este número de la revista encontrarás artículos concretos sobre el uso del agua en la agricultura, las bondades e inconvenientes de diferentes sistemas agrícolas y advertencias a los riesgos de privatización del agua, entre otros. Son temas que, desde la perspectiva de la Soberanía Alimentaria, debemos abordar contestando una pregunta fundamental: para que las y los agricultores puedan alimentar al Planeta y mantenerlo fértil, ¿qué uso y gestión hacemos del Agua?

  4. II Jornadas sobre Emprendimiento Social y Colectivo

    OpenAIRE

    Centro de Investigación en Gestión de Empresas

    2013-01-01

    La línea temática principal del encuentro es el emprendimiento social y colectivo así como las diferentes líneas de investigación de los institutos y centros de la Red relacionadas, como: responsabilidad social, empleo y reincorporación al trabajo, inserción laboral, servicios sociales y dependencia, género, cambios legislativos, utilidad social, medio ambiente, desarrollo local,... Centro de Investigación en Gestión de Empresas (2013). II Jornadas sobre Emprendimiento Social y Colectivo. ...

  5. Efectos del tabaquismo sobre el desarrollo prenatal

    OpenAIRE

    Carnero Cartujo, Sonia

    2014-01-01

    El tabaquismo es un problema de salud pública, causa enfermedad, incapacidad y muerte. El porcentaje de mujeres fumadoras mundialmente, alcanza el 22%. Si este porcentaje se mantiene durante el embarazo, debería tenerse en cuenta que la placenta humana es particularmente permeable a muchos de los compuestos en el humo del tabaco, y que existe suficiente evidencia científica de que los componentes del humo de un cigarrillo tienen efectos muy negativos sobre la vida intrauterina. La mayor parte...

  6. Efecto del Diazepam sobre el desarrollo fetal

    OpenAIRE

    2001-01-01

    El diazepam se absorbe rápida y completamente después de la administración oral y atraviesa la barrera placentaria; su tasa de penetración en el tejido placentario es de 31,5% a las 4 horas, su vida media es prolongada y la existencia de metabolitos activos hace que su efecto sea acumulativo. Este trabajo se realizó en un modelo in vivo, usando 10 mg/Kg/día de diazepam intramuscular, en donde se estudió el efecto del diazepam sobre el desarrollo fetal, utilizando un modelo experimental en el ...

  7. High Expression, Purification and Characterization of cDNA Encoding M3-M4 Loop in the Essential Subuint of hNMDA Receptor%人NMDA受体主亚基M3-M4环基因片段的高效表达、纯化与鉴定

    Institute of Scientific and Technical Information of China (English)

    张玉梅; 孙长凯; 范明; 李伍举; 刘淑红; 赵杰; 韩大跃; 王嘉玺

    2003-01-01

    用基因工程方法获得人N-甲基-D-天冬氨酸(N-methyl-D-aspartate,NMDA)受体主亚基M3-M4环靶片段,以此为免疫原,用于进一步免疫原性及相关应用研究. 自人脑胶质瘤组织中提取总RNA, 采用RT-PCR扩增出人NMDA受体主亚基M3-M4环的基因片段, 并按照计算机辅助原核表达载体pBV220中外源基因高效表达的数学模型预测方法, 将其进行优化改构. 将目的基因克隆到pBV220中,转化大肠杆菌DH5α,升温诱导表达,从蛋白质水平检测重组体在大肠杆菌中的表达情况, 通过制备性SDS-PAGE 进行纯化, 从相对分子质量、免疫反应性、肽质谱指纹分析等方面进行鉴定. 结果表明,成功构建了人NMDA受体主亚基M3-M4环的原核表达载体(命名为pBV-NR1L3),通过基因优化,实现了高效表达.凝胶扫描分析表达量约占菌体总蛋白29 %,重组肽纯度达95 %以上.

  8. Nuevas operaciones binarias sobre los conjuntos borrosos de tipo 2

    OpenAIRE

    Hernández Varela, Pablo Ramón; Cubillo Villanueva, Susana; Torres Blanc, Carmen

    2013-01-01

    Walker et al. ([19], [20]) definieron dos familias de operaciones binarias sobre M (conjunto de las funciones de [0,1] en [0,1]), y determinaron que, bajo ciertas condiciones, estas operaciones son tnormas (normas triangulares) o t-conormas sobre L (subconjunto de las funciones normales y convexas de M). En este trabajo se introducen dos operaciones binarias sobre M, diferentes a las dadas por Walker et al., y se estudian varias propiedades de las mismas, con el objeto de de...

  9. Effects of TGF-β1 on the expression of MMP-1 and MMP-3 mRNA in skin fibroblasts induced by UVA in vitro%TGF-β1对UVA照射人皮肤成纤维细胞MMP-1和MMP-3 mRNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    何永静; 刘垠; 王继华; 赵亚南; 杨云; 李颖

    2010-01-01

    目的:研究转化生长因子-β1(tansforming gowth fctor-beta 1,TGF-β1)对长波紫外线(ultrayiolet A,OVA)照射人皮肤成纤维细胞基质金属蛋白酶-1(matrix metalloproteinasv-1,MMP-1)和基质金属蛋白酶-3(matrix metalloprotein ase-3,MMP-3)mRNA表达的影响,探讨TGF-β1对皮肤成纤维细胞的光保护机制.方法:通过体外培养人皮肤成纤维细胞,加入不同浓度TGF-β1(0.1、1、10ng/m1)预处理细胞后UVA15J/cm2照射诱导细胞光老化,用四甲基偶氮唑蓝(MTT)法检测成纤维细胞增殖活性,半定量逆转录聚合酶链反应(RT-PCR)测定MMP-1、MMP-3mRNA表达. 结果:UVA15J/cm2照射前给予不同剂量TGF-β1预处理,随TGF-β1剂量增加成纤维细胞增殖活性明显提高,MMP-1、MMP-3mRNA表达随着TGF-β1剂量增加而降低.结论:TGF-β1可提高UVA照射体外培养成纤维细胞增殖活性,减少UVA照射体外培养的皮肤成纤维细胞MMP-1、MMP-3 mRNA表达,减少其对胶原的降解,对UVA照射皮肤成纤维细胞起保护作用.

  10. Tributos sobre a folha ou sobre o faturamento? Efeitos quantitativos para o Brasil

    Directory of Open Access Journals (Sweden)

    Tiago V Cavalcanti

    2008-09-01

    Full Text Available Este artigo estuda os impactos alocativos e de bem-estar de uma reforma tributária que substitui os impostos sobre a folha de salários por outro que incide sobre a receita. Para isso, desenvolve-se um modelo neoclássico de crescimento econômico com impostos sobre a receita e sobre a folha de salários. As simulações com parâmetros da economia brasileira mostram que tal reforma tributária tem um efeito negativo no bem-estar, no estoque de capital de longo prazo e consequentemente no produto per capita de longo prazo. Contudo, o emprego aumenta.This paper studies the impacts of a tax reform which substitutes taxes on labor income by taxes on total revenue. In order to accomplish that, we construct and solve a general equilibrium neoclassical growth model with taxes on labor income and total revenue. The numerical simulations with Brazilian parameters show that such tax reforms would negatively affect welfare, the capital stock, and consequently per capita output. However, employment would increase. Such effects are quantitatively important.

  11. Esquemas cognitivos sobre difraccion de ondas mecanicas de estudiantes universitarios

    National Research Council Canada - National Science Library

    Delgado, Mercedes; Arrieta, Xiomara; Melean, Ramon

    2013-01-01

    ...). Su objetivo, es analizar los esquemas utilizados por los estudiantes universitarios en la resolucion de situaciones problematicas sobre difraccion de ondas mecanicas antes de la ensenanza formal...

  12. Influencia mental a distancia sobre los organismos vivientes

    National Research Council Canada - National Science Library

    Bonilla, Ernesto

    2013-01-01

    Este articulo revisa estudios relacionados con la influencia mental a distancia sobre los organismos vivientes, incluyendo las sugestiones mentales de sueno y despertar, la influencia mental a grandes...

  13. Consideraciones criminológicas sobre las bandas juveniles

    OpenAIRE

    Medina, Juanjo

    2010-01-01

    Este artículo ofrece una serie de reflexiones originales sobre la definición de las bandas juveniles y resume algunos de los debates claves en el campo de investigación sobre bandas. En particular, se presta especial atención a los estudios sobre la relación entre bandas y delincuencia, las teorías que explican la formación de las bandas y los factores que empujan a los jóvenes a vincularse a las mismas, los estudios sobre respuestas de política criminal a este fenómeno, ...

  14. Nivel de conocimientos del personal de salud sobre cuidados paliativos

    OpenAIRE

    2012-01-01

    Antecedentes: la medicina paliativa no figura en las prioridades de salud de México; en las instituciones existe un gran desconocimiento sobre las necesidades físicas, psicológicas, sociales y espirituales del paciente en estado terminal y sobre las de su familia; se reconoce que los profesionales de la salud carecen de conocimientos sobre cuidados paliativos. Objetivo: evaluar el nivel de conocimientos que sobre cuidados paliativos tiene el personal de salud de los tres niveles de atención m...

  15. Zero thermal expansion and ferromagnetism in cubic Sc(1-x)M(x)F3 (M = Ga, Fe) over a wide temperature range.

    Science.gov (United States)

    Hu, Lei; Chen, Jun; Fan, Longlong; Ren, Yang; Rong, Yangchun; Pan, Zhao; Deng, Jinxia; Yu, Ranbo; Xing, Xianran

    2014-10-01

    The rare physical property of zero thermal expansion (ZTE) is intriguing because neither expansion nor contraction occurs with temperature fluctuations. Most ZTE, however, occurs below room temperature. It is a great challenge to achieve isotropic ZTE at high temperatures. Here we report the unconventional isotropic ZTE in the cubic (Sc1-xMx)F3 (M = Ga, Fe) over a wide temperature range (linear coefficient of thermal expansion (CTE), αl = 2.34 × 10(-7) K(-1), 300-900 K). Such a broad temperature range with a considerably negligible CTE has rarely been documented. The present ZTE property has been designed using the introduction of local distortions in the macroscopic cubic lattice by heterogeneous cation substitution for the Sc site. Even though the macroscopic crystallographic structure of (Sc0.85Ga0.05Fe0.1)F3 adheres to the cubic system (Pm3̅m) according to the results of X-ray diffraction, the local structure exhibits a slight rhombohedral distortion. This is confirmed by pair distribution function analysis of synchrotron radiation X-ray total scattering. This local distortion may weaken the contribution from the transverse thermal vibration of fluorine atoms to negative thermal expansion, and thus may presumably be responsible for the ZTE. In addition, the present ZTE compounds of (Sc1-xMx)F3 can be functionalized to exhibit high-Tc ferromagnetism and a narrow-gap semiconductor feature. The present study shows the possibility of obtaining ZTE materials with multifunctionality in future work.

  16. σ-Aromatic cyclic M3(+) (M = Cu, Ag, Au) clusters and their complexation with dimethyl imidazol-2-ylidene, pyridine, isoxazole, furan, noble gases and carbon monoxide.

    Science.gov (United States)

    Pan, Sudip; Saha, Ranajit; Mandal, Subhajit; Chattaraj, Pratim K

    2016-04-28

    The σ-aromaticity of M3(+) (M = Cu, Ag, Au) is analyzed and compared with that of Li3(+) and a prototype σ-aromatic system, H3(+). Ligands (L) like dimethyl imidazol-2-ylidene, pyridine, isoxazole and furan are employed to stabilize these monocationic M3(+) clusters. They all bind M3(+) with favorable interaction energy. Dimethyl imidazol-2-ylidene forms the strongest bond with M3(+) followed by pyridine, isoxazole and furan. Electrostatic contribution is considerably more than that of orbital contribution in these M-L bonds. The orbital interaction arises from both L → M σ donation and L ← M back donation. M3(+) clusters also bind noble gas atoms and carbon monoxide effectively. In general, among the studied systems Au3(+) binds a given L most strongly followed by Cu3(+) and Ag3(+). Computation of the nucleus-independent chemical shift (NICS) and its different extensions like the NICS-rate and NICS in-plane component vs. NICS out-of-plane component shows that the σ-aromaticity in L bound M3(+) increases compared to that of bare clusters. The aromaticity in pyridine, isoxazole and furan bound Au3(+) complexes is quite comparable with that in the recently synthesized Zn3(C5(CH3)5)3(+). The energy gap between the highest occupied molecular orbital and the lowest unoccupied molecular orbital also increases upon binding with L. The blue-shift and red-shift in the C-O stretching frequency of M3(CO)3(+) and M3(OC)3(+), respectively, are analyzed through reverse polarization of the σ- and π-orbitals of CO as well as the relative amount of OC → M σ donation and M → CO π back donation. The electron density analysis is also performed to gain further insight into the nature of interaction.

  17. Density functional investigation of metal-metal interactions in d4d4 face-shared [M2Cl9]3 - (M = Mn, Tc, Re) systems.

    Science.gov (United States)

    Cavigliasso, Germán; Stranger, Robert

    2004-04-05

    The molecular and electronic structures of the d(4)d(4) face-shared [M(2)Cl(9)](3)(-) (M = Mn, Tc, Re) dimers have been calculated by density functional methods in order to investigate metal-metal bonding in this series. The electronic structures of these systems have been analyzed using potential energy curves for the broken-symmetry and other spin states arising from the various d(4)d(4) coupling modes, and closed energy cycles have been utilized to identify and quantify the parameters which are most important in determining the preference for electron localization or delocalization and for high-spin or low-spin configurations. In [Tc(2)Cl(9)](3)(-) and [Re(2)Cl(9)](3)(-), the global minimum has been found to be a spin-triplet state arising from the coupling of metal centers with low-spin configurations, and characterized by delocalization of the metal-based electrons in a double (sigma and delta(pi)) bond with a metal-metal separation of 2.57 A. In contrast, high-spin configurations and electron localization are favored in [Mn(2)Cl(9)](3)(-), the global minimum for this species being the ferromagnetic S = 4 state with a rather long metal-metal separation of 3.43 A. These results are consistent with metal-metal overlap and ligand-field effects prevailing over spin polarization effects in the Tc and Re systems, but with the opposite trend being observed in the Mn complex. The ground states and metal-metal bonding observed for the d(4)d(4) systems in this study parallel those previously found for the analogous d(2)d(2) complexes of V, Nb, and Ta, and can be rationalized on the basis that the d(4)d(4) dimer configuration is the hole equivalent of the d(2)d(2) configuration.

  18. High Precision Photometry of Variable Stars in Clusters of Different Ages with the 1.3 m Robotically Controlled Telescope (RCT)

    Science.gov (United States)

    Guinan, E. F.; McCook, G. P.; DeWarf, L. E.; Gelderman, R. F.; McGruder, C. H.; Walter, D. K.; Howell, S. B.; Davis, D. R.; Everett, M.; Mattox, J. R.

    2003-05-01

    We discuss a new program of carrying out high precision VRI CCD photometry of several star clusters of different ages. The photometry is being carried out using the 1.3 m Robotically Controlled Telescope (RCT), located at KPNO. This program focuses on the study of variable stars in mostly open clusters. Selected astrophysically important eclipsing binaries, pulsating variables, blue stragglers, and chromospherically active variable stars will be studied. Also, searches of new variable stars will be made from the expected large samples of cluster stars. For example, photometry is planned of the several W UMa eclipsing binaries and blue straggler stars in the old open cluster NGC 188. Photometry also will be carried out of the young open cluster NGC 7790. This cluster is unique because has three confirmed classical cepheid members: CE Cas A (V ˜ +10.9 mag; F8 Ib; P = 4.446 d ), CE Cep B (V ˜ +11.0 mag; F9 Ib; 5.128 d), and CF Cas (V ˜ +11.1 mag; F8 Ib; 4.875 d). NGC 7790 also contains the 10th mag eccentric B0+B0 eclipsing binary QX Cas. The observations of QX Cas are being conducted to determine the accurate distance to this star and thus to the cluster and its cepheid members. When complete these observations, combined with spectroscopy, will permit a reliable calibration of the ``zero-point'' of the galactic cepheid Period-Luminosity Law. Another possible project is the search of light variations of PMS stars and chromospherically active stars (from star spot rotational modulations) in young clusters such as the alpha Perseus Cluster, h & χ Per, M34, and the Pleiades. Refurbishment of the RCT has been made possible by NASA grant NAG 58762. The RCT Consortium includes: Western Kentucky Univ., S. Carolina St Univ., Francis Marion Univ., Villanova Univ., and the Planetary Science Institute (PSI).

  19. Decreased AMPA GluR2, but not GluR3, mRNA expression in rat amygdala and dorsal hippocampus following morphine-induced behavioural sensitization.

    Science.gov (United States)

    Sepehrizadeh, Zargham; Bahrololoumi Shapourabadi, Mina; Ahmadi, Shamseddin; Hashemi Bozchlou, Saeed; Zarrindast, Mohammad-Reza; Sahebgharani, Mousa

    2008-11-01

    1. Repeated administration of psychostimulants and micro-opioid receptor agonists elicits a progressive enhancement of drug-induced behavioural responses, a phenomenon termed behavioural sensitization. These changes in behaviour may reflect plastic changes requiring regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid (AMPA) receptor function. 2. In the present study, rats were treated for 7 days with saline or morphine (10 mg/kg). After a washout period of either 24 h or 7 days, locomotion, oral stereotypy and state-dependent memory in a passive avoidance test were measured in the presence or absence of 6-cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX; 3 mg/kg), an AMPA receptor antagonist. In order to evaluate the mechanism underlying the behavioural responses, quantitative real-time reverse transcription-polymerase chain reaction was used to evaluate mRNA expression of the AMPA receptor subunits GluR2 and GluR3 in the striatum, prefrontal cortex, hippocampus, hypothalamus and amygdala of animals treated repeatedly with morphine. 3. The results indicate that repeated morphine treatment followed by 7 days (but not 24 h) washout produces behavioural sensitization, as determined by locomotion, oral stereotypy and state-dependent memory. Blockade of AMPA receptors with CNQX on the test day did not alter these behavioural responses. In addition, repeated morphine treatment followed by 7 days (but not 24 h) washout decreased GluR2 mRNA expression in both the amygdala (by 50%) and hippocampus (by 35%). Repeated morphine treatment did not alter GluR3 mRNA expression in any brain area assessed. 4. These data imply that AMPA receptors are involved in the development (but not expression) phase of behavioural sensitization. The decreases in GluR2 mRNA expression in the amygdala and hippocampus may result in the formation of calcium-permeable AMPA receptors, which are believed to play an important role in behavioural sensitization.

  20. Alkaline Earth Metal Zirconate Perovskites MZrO3 (M=Ba(2+), Sr(2+), Ca(2+)) Derived from Molecular Precursors and Doped with Eu(3+) Ions.

    Science.gov (United States)

    Drąg-Jarząbek, Anna; John, Łukasz; Petrus, Rafał; Kosińska-Klähn, Magdalena; Sobota, Piotr

    2016-03-24

    The effect of alkaline earth metal alkoxides on the protonation of zirconocene dichloride was investigated. This approach enabled the design of compounds with preset molecular structures for generating high-purity binary metal oxide perovskites MZrO3 (M=Ba(2+), Sr(2+), Ca(2+)). Single-source molecular precursors [Ba4 Zr2 (μ6 -O)(μ3 ,η(2)-OR)8 (OR)2(η(2) -HOR)2 (HOR)2 Cl4], [Sr4 Zr2 (μ6 -O)(μ3 ,η(2)-OR)8 (OR)2 (HOR)4 Cl4], [Ca4 Zr2 (μ6-O)(μ3 ,η(2)-OR)8 (OR)2 Cl4], and [Ca6 Zr2 (μ2 ,η(2)-OR)12 (μ-Cl)2 (η(2) -HOR)4 Cl6 ]⋅8 CH2 Cl2 were prepared via elimination of the cyclopentadienyl ring from Cp2 ZrCl2 as CpH in the presence of M(OR)2 and alcohol ROH (ROH=CH3OCH2 CH2OH) as a source of protons. The resulting complexes were characterized by elemental analysis, IR and NMR spectroscopy, and single-crystal X-ray diffraction. The compounds were then thermally decomposed to MCl2 /MZrO3 mixtures. Leaching of MCl2 from the raw powder with deionized water produced highly pure perovskite-like oxide particles of 40-80 nm in size. Luminescence studies on Eu(3+)-doped MZrO3 revealed that the perovskites are attractive host lattices for potential applications in display technology.

  1. Fermi-liquid behavior of binary intermetallic compounds Y3 M (M  =  Co, Ni, Rh, Pd, Ir, Pt)

    Science.gov (United States)

    Strychalska-Nowak, Judyta; Wiendlocha, Bartłomiej; Hołowacz, Katarzyna; Reczek, Paula; Podgórski, Mateusz; Winiarski, Michał J.; Klimczuk, Tomasz

    2017-06-01

    A series of polycrystalline samples of Y3 M (M  =  Co, Ni, Rh, Pd, Ir, Pt), intermetallic binary compounds were synthesized by the arc-melting method. Powder x-ray diffraction (pXRD) confirmed the orthorhombic cementite-type crystal structure and allowed for the estimation of the lattice parameters. Physical properties were investigated by means of electrical resistivity and heat capacity measurements between 1.9 K and 300 K. All tested compounds show metallic-like behaviour with RRR values ranging from 1.3 to 8.3, and power-law ρ \\propto {{T}n} temperature dependence of resistivity was observed, with 1.6≤slant n≤slant 2.2 . No superconductivity was detected above 1.9 K. The Debye temperature, estimated from the low temperature heat capacity fit, ranged from 180 K (Y3Pt) to 222 K (Y3Co). The highest value of the Sommerfeld coefficient γ was found for Y3Pd (19.5 mJ mol-1 K-2). The pXRD pattern of Y3Rh indicated the presence of Y5Rh2, a previously unreported Pd5B2-type phase, whose unit cell parameters were refined using the LeBail method. Density functional theory calculations were performed and theoretical results revealed strong enhancement of the measured electronic specific heat, which was 30%-100% larger than computed. Quadratic temperature dependence of resistivity and enhanced electronic specific heat indicated a Fermi-liquid behavior of electrons in these materials.

  2. Photo-initiated thiol-ene click reactions as a potential strategy for incorporation of [M(I)(CO)3]+ (M = Re, (99m)Tc) complexes.

    Science.gov (United States)

    Hayes, Thomas R; Lyon, Patrice A; Silva-Lopez, Elsa; Twamley, Brendan; Benny, Paul D

    2013-03-18

    Click reactions offer a rapid technique to covalently assemble two molecules. In radiopharmaceutical construction, these reactions can be utilized to combine a radioactive metal complex with a biological targeting molecule to yield a potent tool for imaging or therapy applications. The photo-initiated radical thiol-ene click reaction between a thiol and an alkene was examined for the incorporation of [M(I)(CO)3](+) (M = Re, (99m)Tc) systems for conjugating biologically active targeting molecules containing a thiol. In this strategy, a potent chelate system, 2,2'-dipicolylamine (DPA), for [M(I)(CO)3](+) was functionalized at the central amine with a terminal alkene linker that was explored with two synthetic approaches, click then chelate and chelate then click, to determine the flexibility and applicability of the thiol-ene click reaction to specifically incorporate ligand systems and metal complexes with a thiol containing molecule. In the click then chelate approach, the thiol-ene click reaction was carried out with the DPA chelate followed by complexation with [M(I)(CO)3](+). In the chelate then click approach, the alkene functionalized DPA chelate was first complexed with [M(I)(CO)3](+) followed by the conduction of the thiol-ene click reaction. Initial studies utilized benzyl mercaptan as a model thiol for both strategies to generate the identical product from either route to provide information on reactivity and product formation. DPA ligands functionalized with two unique linker systems (allyl and propyl allyl ether) were prepared to examine the effect of the proximity of the chelate or complex on the thiol-ene click reaction. Both the thiol-ene click and coordination reactions with Re, (99m)Tc were performed in moderate to high yields demonstrating the potential of the thiol-ene click reaction for [M(I)(CO)3](+) incorporation into thiol containing biomolecules.

  3. Debate sobre estudios postcoloniales y subalternos

    Directory of Open Access Journals (Sweden)

    David Morris

    2001-01-01

    Full Text Available A partir de los comentarios a la reseña elaborada por Ian S. Mclean sobre el libro: Cuerpos incas y el cuerpo de Cristo. El Corpus Christi en Cuzco colonial, Perú, escrito por Carolyn Dean, surge un debate sobre los Estudios Postcoloniales y Subalternos, que se desarrolló entre el 12 de agosto y el 3 de septiembre de 2001, a través de la lista de correo electrónico de H-Latam, grupo de discusión dedicado a la historia latinoamericana. En él participaron destacados especialistas en el tema, quienes analizaron, entre otras cuestiones, el uso de la jerga y las formas de escritura, la novedad de sus planteamientos, sus influencias filosóficas y epistemológicas, su pretensión de captar el punto de vista de los vencidos y subordinados, la pertinencia de unas ideas originalmente desarrolladas para el estudio del colonialismo inglés y luego aplicadas al colonialismo español en América Latina.

  4. Módulo educativo sobre emergencias escolares

    Directory of Open Access Journals (Sweden)

    Ana María Fajardo-Maldonado

    2009-01-01

    Full Text Available Con el fin de conocer el comportamiento ante emergencias escolares de niñas y adolescentes, se realizó una investigación descriptiva sobre el impacto de un proceso educativo de un programa de salud al colegio. El estudio se adelantó entre el 2007 y el 2008, en la localidad de Suba, en Bogotá, con un grupo de 120 estudiantes, de 6 a 18 años, de estratos cero, uno y dos. Mediante una metodología lúdica, pedagógica y de experiencias se evaluaron los conocimientos impartidos a esta población, en la que se observaron cambios en los estilos de vida y hábitos individuales y grupales. El 95% de las niñas validaron los conocimientos en salud sobre el manejo de emergencias escolares, el 100% de la población participó en la construcción del plan y trabajó en las prácticas, lo que crea conciencia acerca de la importancia del programa de salud escolar con el desarrollo de este tipo de planes.

  5. sobre la representatividad democrática

    Directory of Open Access Journals (Sweden)

    Adriana Gallo

    2008-01-01

    Full Text Available En este trabajo se evalúan los efectos que reviste la aplicación de tres instrumentos sugeridos o implementados, a partir de las últimas reformas político-institucionales –primarias abiertas, sistema de doble vuelta, y reelección inmediata– sobre la representatividad partidaria en Argentina, Chile y Uruguay. La relevancia del análisis de estos mecanismos en conjunto se debe a que, por un lado, cada uno concierne a una de las tres instancias del proceso electivo trifásico –selección, elección y reelección, respectivamente–; y, por otro, los tres comparten objetivos similares que sintéticamente son: dotar de más herramientas de discernimiento político a los ciudadanos, proveer de mejores condiciones democráticas a los partidos e incrementar la legitimidad electoral del presidente. Luego del análisis comparativo de tres países con trazos diferenciados, se concluye que los costos ocultos que pueden suscitarse con cada mecanismo analizado superan a los beneficios potenciales de alguno de ellos, operando negativamente sobre la representatividad democrática.

  6. Concretando la tercera misión (3m de la Universidad Pública Regional. Impactos y percepciones de un proyecto de extensión. Caso Universidad del Magdalena

    Directory of Open Access Journals (Sweden)

    Pablo Hernán Vera Salazar

    2014-08-01

    Full Text Available El propósito de este artículo es presentar un análisis de la orientación asumida por una universidad de la región Caribe colombiana para desarrollar acciones ubicadas en lo que se ha denominado “la tercera misión de la universidad”. Adicionalmente, se hace análisis del efecto generado en la universidad por la ejecución de proyectos de extensión. El enfoque metodológico utilizado fue el de estudio de caso tomando un proyecto de intervención de alcance regional como unidad de análisis. En este contexto, las fuentes de información utilizadas fueron: información documental de la ejecución del proyecto, entrevistas semiestructuradas a los coordinadores del proyecto y una encuesta de percepción sobre la tercera misión dirigida a una muestra de profesores de la universidad. El principal hallazgo de este estudio fue la identificación y caracterización de la orientación asumida por la universidad objeto de estudio para desarrollar la tercera misión con énfasis en el desarrollo social del entorno. Aunque este estudio se limitó a un único caso en un contexto particular, los hallazgos obtenidos permitieron evidenciar algunos rasgos de la materialización de la tercera misión de la universidad, los cuales pueden servir de referencia para desarrollar estudios similares en otros contextos institucionales de la región y del país.Palabras clave: Tercera misión; extensión universitaria; responsabilidad social Universitaria; gestión de proyectos; innovación social.Specifying the third mission (3m of the Regional Public University. Impacts and perceptions of extension project. Case: University of MagdalenaAbstractThe purpose of this paper is to present an analysis of the orientation that is assumed by a university in the Colombian Caribbean region for developing actions in what has been known as “the university’s third mission”. In addition, an analysis about the effect on the university that is generated by the execution of

  7. The 1.3-m Robotically Controlled Telescope (RCT) at Kitt Peak - A Fifty year old dream Realized: Telescope Characteristics, Current Research and Education Progr

    Science.gov (United States)

    Guinan, Edward; Gelderman, Richard; Strolger, Louis-Gregory; Carini, Michael T.; McGruder, Charles, III; Campbell, Rachel; Walter, Donald K.; Davis, Donald R.; Tedesco, Edward F.; Engle, Scott G.

    2011-03-01

    The 1.3 m Robotically Controlled Telescope (RCT) on Kitt Peak has a rich history, including its role as a prototype for remotely controlled telescopes during the 1960s. As such, the RCT could be considered one of the first - Telescopes from Afar. The telescope, originally called the Remotely Controlled Telescope, has been renamed the Robotically Controlled Telescope to reflect the change in operational control and mode of use. The RCT was a conceptual precursor of today's robotic telescopes, but the actual operation of a remotely controlled telescope was technologically premature for its time, and was subsequently manually operated primarily to conduct optical and infrared observations as well being used as a test bed for new spectroscopic and photometric instruments. In 1995 budget constraints forced the closing of the telescope as part of the Kitt Peak National Observatory (KPNO), following nearly 30 years of distinguished service to KPNO. A request for proposals to operate this telescope was issued to the science community. The RCT consortium, lead by Western Kentucky University, was the successful proposer for operation of the telescope. After several difficult years of retrofitting, refurbishing, and automating the telecope and observatory dome, the telescope has returned to routine science operations in November 2009. The RCT has operated smoothly since that time, with no major interruptions. Observations of objects of interest to the consortium partners (including: comets & asteroids, variable & binary stars, exoplanets, supernovae, quasars & blazars) are being routinely obtained and evaluated. One of the distinguishing features of the RCT is that it is an autonomous observatory designed to handle diverse optical imaging and photometry programs. These include being able to automatically deal with a wide range of observing parameters such as -integration time, sky conditions, repetitions, return visits, filters, air mass, non-sidereal objects, transients etc

  8. Elastic relaxations associated with the Pm3m-R3c transition in LaA103 III: superattenuation of acoustic resonances

    Energy Technology Data Exchange (ETDEWEB)

    Darling, Timothy W [Los Alamos National Laboratory; Carpenter, M A [UNIV OF CAMBRIDGE; Buckley, A [UNIV OF CAMBRIDGE; Taylor, P A [UNIV OF CAMBRIDGE; Mcknight, R E A [UNIV OF CAMBRIDGE

    2009-01-01

    Resonant Ultrasound Spectroscopy has been used to characterize elastic softening and a variety of new acoustic dissipation processes associated with the Pm{bar 3}m {leftrightarrow} R{bar 3}c transition in single crystal and ceramic samples of LaAlO{sub 3}. Softening of the cubic structure ahead of the transition point is not accompanied by an increase in dissipation but follows different temperature dependences for the bulk modulus, 1/3(C{sub 11} + 2C{sub 12}), and the shear components 1/2(C{sub 11}-C{sub 12}) and C{sub 44} as if the tilting instability contains two slightly different critical temperatures. The transition itself is marked by the complete disappearance of resonance peaks (superattenuation), which then reappear below {approx}700 K in spectra from single crystals. Comparison with low frequency, high stress data from the literature indicate that the dissipation is not due to macroscopic displacement of needle twins. An alternative mechanism, local bowing of twin walls under low dynamic stress, is proposed. Pinning of the walls with respect to this displacement process occurs below {approx}350 K. Anelasticity maps, analogous to plastic deformation mechanism maps, are proposed to display dispersion relations and temperature/frequency/stress fields for different twin wall related dissipation mechanisms. An additional dissipation process, with an activation energy of 43 {+-} 6 kJ.mole{sup -1}, occurs in the vicinity of 250 K. The mechanism for this is not known, but it is associated with C{sub 44} and therefore appears to be related in some way to the cubic {leftrightarrow} rhombohedral transition at {approx}817 K. Slight softening in the temperature interval {approx}220 {yields} 70 K of resonance peaks determined by shear elastic constants hints at an incipient E{sub g} ferroelastic instability in LaAlO{sub 3}. The softening interval ends with a further dissipation peak at {approx} 60 K, the origin of which is discussed in terms of freezing of atomic

  9. BTG/Tob family members Tob1 and Tob2 inhibit proliferation of mouse embryonic stem cells via Id3 mRNA degradation

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yuanfan; Wang, Chenchen [Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191 (China); Peking University Stem Cell Research Center, China National Center for International Research, Peking University Health Science Center, Beijing 100191 (China); SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, University of Chinese Academy of Sciences, Shanghai 200120 (China); Wu, Jenny [SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, University of Chinese Academy of Sciences, Shanghai 200120 (China); Li, Lingsong, E-mail: lils@sari.ac.cn [Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191 (China); Peking University Stem Cell Research Center, China National Center for International Research, Peking University Health Science Center, Beijing 100191 (China); SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, University of Chinese Academy of Sciences, Shanghai 200120 (China)

    2015-07-03

    The mammalian BTG/Tob family is a group of proteins with anti-proliferative ability, and there are six members including BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. Among them, Tob subfamily members, specifically Tob1/Tob and Tob2, have the most extensive C-terminal regions. As previously reported, overexpression of BTG/Tob proteins is associated with the inhibition of G1 to S-phase cell cycle progression and decreased cell proliferation in a variety of cell types. Tob subfamily proteins have similar anti-proliferative effects on cell cycle progression in cultured tumor cells. An important unresolved question is whether or not they have function in rapidly proliferating cells, such as embryonic stem cells (ESCs). Tob1 and Tob2 were expressed ubiquitously in mouse ESCs (mESCs), suggesting a possible role in early embryonic development and mESCs. To address the above question and explore the possible functions of the Tob subfamily in ESCs, we established ESCs from different genotypic knockout inner cell mass (ICM). We found that Tob1{sup −/−}, Tob2{sup −/−}, and Tob1/2 double knockout (DKO, Tob1{sup −/−} & Tob2{sup −/−}) ESCs grew faster than wild type (WT) ESCs without losing pluripotency, and we provide a possible mechanistic explanation for these observations: Tob1 and Tob2 inhibit the cell cycle via degradation of Id3 mRNA, which is a set of directly targeted genes of BMP4 signaling in mESCs that play critical roles in the maintenance of ESC properties. Together, our data suggest that BTG/Tob family protein Tob1 and Tob2 regulation cell proliferation does not compromise the basic properties of mESCs. - Highlights: • We established mouse Tob1/2 double knockout embryonic stem cells. • Tob1 and Tob2 inhibit the proliferation of ESCs without effect on pluripotency. • Tob1 and Tob2 involved in the degradation of Id3 in mESCs.

  10. The central dynamics of M3, M13, and M92: stringent limits on the masses of intermediate-mass black holes

    Science.gov (United States)

    Kamann, S.; Wisotzki, L.; Roth, M. M.; Gerssen, J.; Husser, T.-O.; Sandin, C.; Weilbacher, P.

    2014-06-01

    We used the PMAS integral field spectrograph to obtain large sets of radial velocities in the central regions of three northern Galactic globular clusters: M3, M13, and M92. By applying the novel technique of crowded field 3D spectroscopy, we measured radial velocities for about 80 stars within the central ~10″ of each cluster. These are by far the largest spectroscopic datasets obtained in the innermost parts of these clusters up to now. To obtain kinematical data across the whole extent of the clusters, we complement our data with measurements available in the literature. We combine our velocity measurements with surface brightness profiles to analyse the internal dynamics of each cluster using spherical Jeans models, and investigate whether our data provide evidence for an intermediate-mass black hole in any of the clusters. The surface brightness profiles reveal that all three clusters are consistent with a core profile, although shallow cusps cannot be excluded. We find that spherical Jeans models with a constant mass-to-light ratio provide a good overall representation of the kinematical data. A massive black hole is required in none of the three clusters to explain the observed kinematics. Our 1σ (3σ) upper limits are 5300 M⊙ (12 000 M⊙) for M3, 8600 M⊙ (13 000 M⊙) for M13, and 980 M⊙ (2700 M⊙) for M92. A puzzling circumstance is the existence of several potential high velocity stars in M3 and M13, as their presence can account for the majority of the discrepancies that we find in our mass limits compared to M92. Based on observations collected at the Centro Astronómico Hispano-Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Appendices are available in electronic form at http://www.aanda.orgTables D.1 to D.6 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc

  11. Hábitos de consumo sobre la cerveza

    OpenAIRE

    Velasco Matilla, Débora

    2015-01-01

    Estudio de los hábitos de consumo de cerveza en un pueblo determinado situado en la provincia de Segovia, Cantalejo. Contiene un resumen sobre la historia de la cerveza y su tipología y un estudio de mercado sobre la cerveza partiendo de una encuesta. Grado en Comercio

  12. Violência sobre Crianças

    OpenAIRE

    Sacadura, Catarina Brito; Aragão, Maria José

    2014-01-01

    Trata-se de um estudo de revisão sobre a violência exercida sobre crianças, os agentes da violência, os sujeitos da violência, os factores de risco, as consequências na idade adulta e a recidividade de violência sexual.

  13. Generalizaciones y creencias sobre el autismo: estudio descriptivo

    OpenAIRE

    Rodríguez Fernández, Patricia

    2015-01-01

    La autora propone una investigación sobre las creencias más generalizadas en diferentes aspectos del autismo: etiología, características, escolarización y pronóstico en diferentes grupos de edades con distinta familiaridad sobre este trastorno y con distinto nivel educativo general.

  14. Quine y Davidson: sobre la evidencia

    Directory of Open Access Journals (Sweden)

    William Duica

    2004-01-01

    Full Text Available Este articulo es un intento por analizar la discusión sostenida por Quine yDavidson sobre la teoría de la evidencia. Con base en el análisis que de estadiscusión hace Koppelberg, trato de mostrar que las críticas de Davidson aQuine no llevan a Davidson a un coherentismo insostenible. Tras este análi-sis terminaré mostrando que la opción de Davidson por el coherentismoencuentra un importante complemento en su teoría distal de la evidencia.Sostendré, entonces, que la combinación de distalismo y coherentismo es loque le permite a Davidson ser un realista acerca del conocimiento empírico

  15. Reflexiones sobre contabilidad privada y contabilidad nacional

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    José Arturo Gutiérrez

    1995-01-01

    Full Text Available Se discuten las interrelaciones de la contabilidad privada y la contabilidad nacional, insistiendo en sus condicionantes internos contradictorios en relación con la sobredeterminación de la formación económico-social vigente. En relación con ello se introduce la reflexión sobre la unidad contradictoria entre empresa y capital, esto es, la base técnica frente a su determinante socioeconómico, conflicto que la propia contabilidad privada expresa: al describir el capital aporta necesariamente el conocimiento de la producción social. De allí su probable compatibilidad con el propósito de la contabilidad nacional, y, por extensión, ambiental.

  16. Reflexiones sobre el tratamiento ambulatorio de drogodependientes.

    Directory of Open Access Journals (Sweden)

    Juan Carlos González García

    1989-01-01

    Full Text Available Intentamos plantear algunas de las innumerables contradicciones, paradojas y mitos que se presentan en relación con las demandas y con las necesidades terapéuticas de los consumidores de drogas, desde el nivel de atención extrahospitalaria pública y dentro de una Unidad de Salud Mental. Se intenta reflexionar sobre los conocimientos teóricos y la realidad práctica, su interdependencia, complementariedad y divergencia, con la finalidad de evitar la huida asistencial o la omnipotencia terapéutica. Se valoran las diferencias existentes entre la farmacología teórica, anclada en el paradigma lewiniano, y la realidad clínica.

  17. Algunas consideraciones sobre las leyes de Indias

    Directory of Open Access Journals (Sweden)

    Juan Friede

    1964-12-01

    Full Text Available La población aborigen de América planteó a la corona un complejo problema social de difícil solución. El Estado español, por carecer de recursos económicos, tuvo que acudir a la iniciativa privada para realizar los propósitos económicos y políticos de la Conquista, es decir, tomar posesión del Nuevo Mundo, poblarlo de cristianos, explotar sus riquezas naturales e integrar a la población vencida a la nueva sociedad hispanoamericana que se estaba formando; reservándose la fiscalización y plena jurisdicción sobre sus flamantes colonias.

  18. naturales: aprendiendo sobre un producto regional

    Directory of Open Access Journals (Sweden)

    Sandra Vázquez

    2008-01-01

    Full Text Available En este trabajo presentamos una estrategia basada en el modelo integrativo, el marco Ciencia–Tecnología–Sociedad (CTS y los intereses de los alumnos. El bajo interés mostrado por las ciencias nos lleva a indagar sobre una propuesta que logre motivar lo suficiente para alcanzar un aprendizaje significativo, integrando contenidos conceptuales correspondientes a distintos espacios curriculares. El tema que trabajamos para llegar a integrar y relacionar Ciencia, Tecnología y Sociedad fue los productos regionales y a partir de un diagnóstico realizado a los alumnos seleccionamos la elaboración de vino y contenidos vinculados con éste. Realizamos una aplicación piloto con una muestra de estudiantes de segundo año de polimodal (16 a 18 años y los resultados logrados fueron satisfactorios.

  19. Sobre a moralidade do direito em Kant

    Directory of Open Access Journals (Sweden)

    Joãosinho Beckenkamp

    2009-07-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2009v8n1p63Na atual literatura sobre a fi losofi a prática de Kant há uma tendência a negligenciar a distinção feita na Metaphysik der Sitten entre direito (Jus e ética (Ethica, a ponto de ser a doutrina do direito de Kant vista como uma mera aplicação do imperativo categórico. Este artigo procura mostrar que Kant apresenta em sua doutrina do direito uma série de argumentos que logram estabelecer o direito de modo inteiramente independente da ética.

  20. Documentos sobre aniversarios, reparticiones y capellanes

    Directory of Open Access Journals (Sweden)

    José Luis Martín Rodríguez

    1989-01-01

    Full Text Available En el Cómpoto o Arte de contar del cabildo segoviano  se habla de la mayordomía de Reparticiones que administra los bienes dejados para la celebración de aniversarios por el alma de los benefactores de la iglesia, y es de suponer que el volumen alcanzado por este tipo de donaciones llevaría a los demás cabildos peninsulares a individualizar estas rentas y a incluir en los libros de Obituarios o Aniversarios las obligaciones contraías por el cabildo, es decir por las dignidades o personas, canónigos y racioneros, que forman el cabildo en sentido estricto, y por los auxiliares de éstos: capellanes, sochantre, mozos de coro, organista, portero, campanero, refitolero, barrendero, perrero... sobre cuyas obligaciones y situación estamos mal informados.

  1. Conceptos fundamentales sobre el mantenimiento de edificios

    Directory of Open Access Journals (Sweden)

    Juan Miguel Arencibia Fernández

    2007-01-01

    Full Text Available En esta investigación se realiza una profunda búsqueda sobre el tema del Mantenimiento de Edificios donde se abundan diferentes conceptos y criterios de la misma, encontrándose de esta forma los más utilizados métodos a emplear. Luego teniendo en cuenta las clasificación del Mantenimiento de Edificio según los tipos de obras, propietarios del inmueble y el momento que éste se realiza, como los costos de una edificación y su equipamiento a utilizar. Otros de los aspectos a tener en cuenta es la organización del Mantenimiento su planificación y responsabilidad, las ventajas que puede traer tanto para la economía y para el mismo usuario, como su vida útil, para el cual fueron ejecutadas las edificaciones.

  2. Algunas reflexiones sobre el turismo cultural

    Directory of Open Access Journals (Sweden)

    Claudia Toselli

    2006-01-01

    Full Text Available El presente artículo, si bien no pretende hacer un análisis exhaustivo sobre el turismo cultural, tiene por objetivo presentar algunas reflexiones acerca de esta modalidad turística desde diferentes aspectos. En primer lugar se abordará la relación entre turismo cultural y globalización, para luego centrarse en la incidencia de esta actividad como factor de desarrollo local y regional, haciendo referencia a algunos ejemplos de Argentina. Intentará también introducir acerca de los aspectos positivos y negativos, o puntos fuertes y débiles del turismo cultural. Y por último, esbozará algunas consideraciones acerca del rol de las organizaciones internacionales y de las principales agencias de cooperación internacional, incluyendo las resoluciones, declaraciones y recomendaciones más significativas en este campo del turismo.

  3. Zubiri et alii sobre la consciencia

    Directory of Open Access Journals (Sweden)

    Solari, Enzo

    2016-08-01

    Full Text Available In recent literature on science and philosophy related to consciousness, the description and analysis are not always appropriate for the phenomenical consciousness that one wants to explain. From this one can sustain, contrary to some approaches to neuroscience and analytic philosophy, that the fact of consciousness previously requires a better phenomenological description and a more precise conceptual analysis.En la reciente literatura científica y filosófica sobre la consciencia no siempre se describe ni analiza adecuadamente cuál es esa consciencia fenoménica que se desea explicar. De ahí que se argumente, contra ciertas aproximaciones de la neurociencia y la filosofía analítica, que el hecho de la consciencia necesita previamente de una mejor descripción fenomenológica y de una más ajustada analítica conceptual.

  4. NOTAS SOBRE A LÓGICA ESTOICA

    Directory of Open Access Journals (Sweden)

    Valter Duarte Moreira Júnior

    2014-02-01

    Full Text Available Diante do grande desenvolvimento da Lógica e do cálculo proposicional no século XX, estudiosos do assunto em todo o mundo se concentraram em um rigoroso estudo dessa disciplina e sua história. Nesse processo, o eminente lógico polonês Jan Lukaziewicz descobriu em sua pesquisa sobre história da lógica a Lógica Estoica, que, já em III a. C., havia antecipado diversos métodos e conceitos da Lógica Moderna. Nossa intenção neste artigo é fazer um breve esboço da lógica desenvolvida pelos Estoicos.

  5. Neruda e Drummond: um olhar sobre Stalingrado

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    Moacir Lopes de Camargos

    2015-07-01

    Full Text Available Este artigo tem por objetivo promover uma aproximação entre dois expoentes da lírica latino-americana do século XX, a saber: Pablo Neruda e Carlos Drummond de Andrade, a partir da análise dos poemas Canto a Stalingrado (1942 e Carta a Stalingrado (1943. Apresentaremos a visão histórica desses poetas sobre a Batalha de Stalingrado, considerada um dos principais eventos da Segunda Guerra Mundial. Ademais, será abordada a questão do engajamento político, que envolve a produção poética dos referidos autores.

  6. Sobre la idea de ciencia en fisioterapia

    OpenAIRE

    Meroño Gallut, Antonio Javier

    2005-01-01

    Sobre la pregunta ¿es la fisioterapia una ciencia?, de forma tácita podríamos asegurar que no, y que además no cabe de ello ninguna duda. Este simple hecho de determinación puede quedar un poco más claro si comparamos a la fisioterapia con una ciencia formal y madura como las matemáticas, o una ciencia también considerada madura pero en este caso experimental como la física; o incluso con otras ciencias naturales de carácter experimental como la biología o la química. El objetivo ...

  7. Refletindo sobre as redes sociais digitais

    Directory of Open Access Journals (Sweden)

    Sônia Cristina Vermelho

    2014-03-01

    Full Text Available Este artigo apresenta os resultados da primeira etapa da investigação realizada pelo grupo de pesquisa Ciência, Tecnologia e Sociabilidade do Mestrado em Promoção da Saúde. Nele situamos a área da Promoção da Saúde; em seguida apresentamos uma discussão em torno do conceito de "redes sociais digitais" e, finalmente, apresentamos alguns resultados da pesquisa bibliográfica realizada nesta etapa. Os dados bibliográficos encontrados (artigos, teses e dissertações indicaram um aumento de trabalhos publicados sobre o tema a partir de 2005, bem como uma concentração nas áreas de Comunicação e Educação.

  8. Escritos sobre la codificación

    OpenAIRE

    Caroni, Pio

    2012-01-01

    Traducción de Adela Mora Cañada y Manuel Martínez Neira Esta publicación ofrece una antología representativa de ensayos, escritos en el arco de treinta años, destinados a ilustrar luces y sombras del proceso codificador. El autor ve en éste no sólo una reorganización formal de la materia jurídica (penal, civil, mercantil o procesal) destinada a garantizar certeza, y por ello dirigida a conseguir mayor completitud material, sino también (y sobre todo) la visible repercusión jurídica de un c...

  9. NOTAS SOBRE A LÓGICA ESTOICA

    OpenAIRE

    Valter Duarte Moreira Júnior

    2014-01-01

    Diante do grande desenvolvimento da Lógica e do cálculo proposicional no século XX, estudiosos do assunto em todo o mundo se concentraram em um rigoroso estudo dessa disciplina e sua história. Nesse processo, o eminente lógico polonês Jan Lukaziewicz descobriu em sua pesquisa sobre história da lógica a Lógica Estoica, que, já em III a. C., havia antecipado diversos métodos e conceitos da Lógica Moderna. Nossa intenção neste artigo é fazer um breve esboço da lógica desenvolvida pelos Estoicos....

  10. Sobre el Boletín

    Directory of Open Access Journals (Sweden)

    Andrés Arias

    2007-04-01

    Full Text Available En la página de Internet de la Biblioteca Luis Ángel Arango se indica que una de la funciones principales del Boletín es la de reseñar la novedades bibliográfica que van apareciendo en el país. "Novedades": de lo nuevo, tanto en las publicaciones como en las reseñas. Es decir, si lo que asegura la página de la Biblioteca es cierto, quien se acerca al Boletín debe encontrarse con comentarios recientes sobre libros recientes. Con guía que le ayuden a elegir entre las mil ofertas que hay en el mercado bibliográfico. Pero bien sabemos que este objetivo no se cumple.

  11. Apuntes sobre el Cultivo del Cacao

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    Ochoa Horacio

    1940-03-01

    Full Text Available Por muchos años permaneció el cultivo del cacao en nuestro país, en un deplorable atraso técnico; el agricultor a duras penas si tenía conocimientos generales de su explotación y, de una industria que tuvo su auge debido a la extensividad de las plantaciones, hoy sólo resta una reducida porción de ella. ¿Qué factores operaron esa tan notoria reducción hasta el punto de que exportadores en otros tiempos nos convertimos en importadores obligados de ese producto? Hay muchas razones de orden técnico y de orden económico. Los cacaotaleros obtenían halagadoras retribuciones cuando el jornal consistía en la alimentación que se le daba a la peonada y cuando, generoso, añadía una sobretasa en dinero. Bajo ese sistema de explotación, el descuadre que pudiera ocasionar tanto las enfermedades criptogámicas como los plagas, no era suficiente como para provocar el pesimismo en el hacendado y por tanto inducirlo al abandono de la plantación. A medida que las condiciones sociales del campesino se fueron modificando y su standard de vida aumentaba, cambió fundamentalmente el mecanismo de la industria Se observó entonces que los árboles morían y que era pobre la producción; que lo que en tiempos pasados fuera un negocio lucrativo, se les había convertido en una actividad improductiva y, para controlar estos fenómenos que se generalizaban en todas las zonas cacaotaleras, opusieron la ignorancia, el rutinarismo y la desidia. Lentamente se han ido modificando los conceptos antiguos sobre el trabajo cultural y los cuidados que con relación a las enfermedades y plagas requiere este delicado cultivo; la rutina está echando paso atrás y las experiencias científicas que procuran la prosperidad del plantío, se ponen en práctica en algunas zonas . Esto da esperanza para la reconstitución de la industria cacaotalera en nuestro país, que cuenta con inmensas regiones de óptima calidad para hacerla florecer sobre bases nuevas, con

  12. Aspectos da pesquisa sobre tipologia textual

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Travaglia

    2014-03-01

    Full Text Available Este artigo chama a atenção dos pesquisadores sobre tipologiatextual, na área da Linguística Textual, sobre aspectos que sãoimportantes para que estas pesquisas gerem conclusões egeneralizações mais confiáveis. Os pontos comentados são: a anecessidade de uma teoria tipológica geral de textos que inclusivedetermine se as categorias de texto são todas da mesma natureza. Oautor propõe uma teoria geral; b a necessidade de estudos maishorizontalizados ou amplos que estabeleçam campos de pesquisa ede estudos mais verticalizados, que aprofundam o conhecimentode pontos específicos; c os aspectos metodológicos para superarproblemas no levantamento das categorias de texto existentes emuma sociedade e cultura, em suas diversas comunidades discursivase esferas de ação social; d a questão dos parâmetros e critérios paraconsiderar uma categoria de texto como sendo uma categoria e seela é de determinada natureza; e a questão dos critérios e parâmetrospara a caracterização das categorias de texto; f a necessidade deestudar as diversas relações de diferentes tipos que podem ocorrerentre as categorias de texto (de diferentes naturezas, tanto em suacomposição quanto em seu funcionamento sociodiscursivo; e g aatenção que merece a questão teminológica.

  13. Changes in uncoupling protein-2, 3 mRNA expression in the scalded rats after escharectomy at different post scalding stages%大鼠烫伤后不同时间切痂骨骼肌解偶联蛋白2、3 mRNA表达水平的改变

    Institute of Scientific and Technical Information of China (English)

    李峰; 郭振荣; 柴家科; 盛志勇

    2004-01-01

    目的观察烫伤大鼠伤后不同时间切痂其骨骼肌解偶联蛋白(UCP)2、UCP3 mRNA表达水平的异同. 方法选用120只雄性Wistar大鼠,其中8只作为正常对照组;余下112只造成30%TBSAⅢ度烫伤后分成4组:A组不切痂,分别于伤后8、24、96、120、168 h处死;B组伤后8 h切痂,于伤后24、96、120、168 h处死;C组伤后24 h切痂,伤后96、120、168 h处死;D组伤后96 h切痂,伤后120、168 h处死.测定各组大鼠各时相点的血清瘦素、肿瘤坏死因子(TNF)α含量以及腓肠肌UCP2、UCP3 mRNA表达水平. 结果 (1)血清瘦素水平:A组大鼠伤后24~168 h均低于正常对照组(P<0.01),B、C、D组伤后120 h和(或)168 h均高于A组(P<0.01).(2)血清TNF-α水平:A组伤后各时相点均高于正常对照组(P<0.01),B组伤后各时相点均低于A组(P<0.05或0.01).C组伤后168 h低于A组(P<0.05).(3)腓肠肌UCP2 mRNA的表达量:A组大鼠在烫伤后8 h即已明显升高(P<0.01),24 h到达高峰,以后逐渐下降.B、C组伤后168 h时分别为0.32±0.20、0.35±0.15,明显低于同时相点A组 0.71±0.12(P<0.05).各组腓肠肌UCP3 mRNA表达的变化趋势与UCP2类似. 结论大鼠严重烫伤后UCP2、UCP3 mRNA表达上调可能是代谢率升高的重要因素之一,休克期切痂可降低这一表达,降低代谢率.

  14. The expression levels of T -bet mRNA and GATA3 mRNA in peripheral blood of patients with preeclampsia%子痫前期患者外周血T - bet mRNA和GATA3mRNA的表达水平

    Institute of Scientific and Technical Information of China (English)

    李净; 杨海澜; 何银芳

    2011-01-01

    目的:从Th细胞特异性转录因子T- bet和GATA3的角度探讨其在子痫前期(pre - eclampsia)发病过程中可能的病理生理机制,为子痫前期的病因研究及免疫治疗提供思路.方法:采集正常产妇和子痫前期患者外周血单个核细胞(PBMCs),提取总RNA,逆转录成cDNA,利用SYBRGreenl荧光定量PCR方法,以β- actin为内对照基因检测每组PBMCs中T-bet mRNA和GATA3 mRNA的表达水平.结果:①GATA3 mRNA在正常妊娠组、子痫前期轻度组和子痫前期重度组的表达随病情的加重表达减弱,子痫前期重度组与正常妊娠组相比差异有统计学意义(P<0.05),子痫前期轻度组与正常妊娠组、子痫前期重度组比较差异无统计学意义(P>0.05);②T - bet mRNA的表达随病情的加重表达增强,子痫前期重度组与正常妊娠组、子痫前期轻度组相比差异有统计学意义(P<0.05),子痫前期轻度组的表达也高于正常妊娠组,但差异无统计学意义(P>0.05);③T - bet mRNA/GATA3 mRNA比值结果显示,随病情的加重比值增大,且子痫前期重度组与正常妊娠组比较差异有统计学意义(P<0.05),子痫前期轻度组与正常妊娠组、子痫前期重度组相比差异无统计学意义(P>0.05).结论:子痫前期患者外周血中表现为免疫杀伤的Th1型细胞转录因子T- bet mRNA表达增强,表现为免疫保护或免疫营养的Th2型细胞转录因子GATA3 mRNA表达减弱,提示子痫前期患者外周血中T- bet mRNA的高表达与其发病有关,GATA3 mRNA在子痫前期的发生、发展中的作用不如T - bet mRNA明显;T- bet mRNA/GATA3 mRNA比值随病情的加重而增大,提示外周血中Th1/Th2转录因子的平衡偏离可能是导致子痫前期发病的病因之一.%Objective: To explore the probable pathogenesis of preeclampsia from the point of T - bet and GATA3, provide ideas for etiological research and immune therapy of preeclampsia Methods: Mononuclear cells were obtained

  15. Reflexiones sobre la crisis. Vidas y Memorias

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    Estela Vázquez

    2009-11-01

    Full Text Available El artículo se plantea analizar la deslegitimación de la política y de los políticos, así como del acto de votar. Encuadrado en el marco del contexto de la crisis argentina de los últimos años, quiere responder, por medio de la entrevista oral y la historia de vida, a cómo se ve desde la ciudadanía el ejercicio de la democracia, las prácticas políticas, la alternancia en el poder y de qué forma todo esto influye en las vidas personales de los entrevistados. Asimismo, se entrelaza el análisis del espectáculo político con el público que ofrecen los medios de comunicación y de entretenimiento, con lo que se viene a concluir que es cada vez más difícil distinguir en el debate social la ficción de los hechos y personajes verdaderamente reales. Para este trabajo se analizan tres trayectorias laborales de ex-empleados de la administración pública, y sus apreciaciones sobre el despido, vinculando estas experiencias de vida a la formación de sus ideas sobre la política y los políticos.. Sus lugares de trabajo eran el Registro Civil, la Secretaría de Educación y la Legislatura, respectivamente.__________________ABSTRACT:This article tries to analyse the discredit of politics and politicians along with the act of voting. Placed in the context of the Argentine crisis, it wants to determinate through oral interview and life story how citizens see the exercise of democracy, the political practices and the power switching, to establish how they have influenced in the lifes of the persons being interviewed. At the same time, it interlaces an analysis of he political spectacle shown to the public by the media, to conclude that is becoming more a more difficult to distinguish the fiction from the real characters in the social debate.

  16. El puente Bendorf sobre el Rin (Alemania

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    Hirschfeld, Kurt

    1966-03-01

    Full Text Available This recently completed bridge over the Rhine is 524 m long, and is a reinforced concrete structure, built by successive overhangs, without the aid of formwork or scaffolding. The centre span is 208 m in length, and the other six vary between 43 and 71 m. The deck consists of two independent parts, including a continuous box girder, with a hinge at the crown of the main span. It is stiffened with transversal diaphragms, spaced every 34 m. The piles rest on pneumatic caissons, which go down to 16 m below the river bed. The attachment between the piles and the caissons is rigid, at the central pile, and at the other piles it operates through a roller bearing. The central span was constructed without intermediate supports for the first 40 m, and beyond that stage, for greater safety, a provisional movable tower was built, as a temporary point of support for the free overhang. The various sections were concreted and post-tensioned with 32 mm bars, by the Dywidag procedure. Account was taken of the varying deformations that took place at each section, so as to add the necessary counter-deflection that finally enabled the two sides of the arch to meet at the crown at the calculated point.Este puente, recientemente construido, sobre el Rin, tiene una longitud total de 524 m, es de hormigón armado y se ha realizado por el procedimiento de voladizos sucesivos, sin entramado auxiliar ni cimbras. La luz del tramo central es de 208 m, y las de los otros seis oscilan entre 43 y 71 m. La estructura del tablero se compone de dos partes independientes, formadas por una viga tipo cajón, continua, con una articulación en la clave del tramo central y rigidizada con diafragmas transversales espaciados a 34 m. Las pilas centrales se apoyan sobre cajones neumáticos que descienden 16 m debajo del fondo del río. La unión entre estas pilas y la estructura cajón es rígida, y de tipo rodillo en las otras pilas. El tramo central se ha construido por voladizos

  17. Algunas reflexiones sobre el poder itinerante almohade.

    Directory of Open Access Journals (Sweden)

    Maribel FIERRO

    2009-12-01

    Full Text Available La primera parte del artículo consiste en la presentación de dos estudios sobre el poder itinerante en el Magreb: Jocelyne Dakhlia (1988 para las épocas hafsí y posteriores; Manuela Marín (2005 sobre el caso almohade. En la segunda parte, primeramente se analiza la convergencia del itinerario de Ibn Tumart con las conquistas de ‘Abd al-Mu’min: el movimiento –real o legendario– del fundador mesiánico del imperio marca el territorio conquistado por su sucesor el califa y su presencia inserta el espacio en la memoria, la geografía y el poder imperiales. A continuación, se plantea la compleja cuestión de la «capitalidad» almohade: se puede hablar de una capital sagrada (Tinmal, una capital central (Marrakech, capitales regionales (Sevilla, Túnez y de una nueva capital inacabada (Rabat. Pero es la presencia (hadar del propio califa la que determina dónde está el centro del imperio.La première partie de cet article présente deux études sur le pouvoir itinérant au Mahgreb : celle de Jocelyne Dakhlia (1986 sur la période hafside et les suivantes, celle de Manuela Marín (2005 sur le cas almohade.Dans la seconde partie, on analyse d’abord la convergence de l’itinéraire d’Ibn Tumart avec les conquêtes d’‘Abd al-Mu’min : le  trajet – réel ou légendaire – du fondateur messianique de l’empire marque le territoire conquis par son successeur le calife et sa présence ancre l’espace dans la mémoire, la géographie et le pouvoir impériaux. Ensuite, on examine la question complexe de la « capitalité » almohade : on peut parler d’une capitale sacrée (Tinmal, d’une capitale centrale (Marrakech, de capitales régionales (Séville, Tunis et d’une nouvelle capitale inachevée (Rabat. Mais c’est la présence (hadar du calife lui-même qui détermine où est le centre de l’empire.

  18. Measurement uncertainty evaluation of 3M PetrifilmTM aerobic count plate method for drinking water%生活饮用水3M PetrifilmTM菌落总数测试片法的不确定度评定

    Institute of Scientific and Technical Information of China (English)

    谭和平; 叶德萍; 沈兴中; 唐祥凯; 王智

    2012-01-01

    3M PetrifilmTM菌落总数测试片法检测生活饮用水中菌落总数的测量结果进行了不确定度评定,评述了引起测量结果不确定度的主要因素,对样品稀释及方法精密度因素进行了详细评价,并对单一样品重复测量10次及30个样品每个样品平行测量2次的两种情况,分别进行了重复性标准偏差评价.结果显示:单一样品重复测量时,测量结果的不确定度主要由样品稀释和重复性标准偏差引起,扩展不确定度U95为20 CFU/mL,k=2;多个样品每个样品平行测量2次时,测量结果的不确定度主要由重复性标准偏差引起,在95%的置信度时,扩展不确定度U(/lgxj)为0.093,k=2.75.%The aerobic plate count in drinking water was determined with 3M Petrifilm? Aerobic count plate, and their measurement uncertainties were evaluated in this study. Firstly, the main components of measurement uncertainty were discussed and analyzed. Then, two most important components, sample dilution and measurement precision were evaluated in detail. And for the precision, the authors evaluated two kinds of precision commonly used in routine work, the repeatability of 10 repeated measurements of single sample and those of double repeated measurements of thirty samples. Experimental results show the sample dilution affects the measurement uncertainty obviously for the case of single-sample test, and the standard deviation of repeated measurement is the most important source of uncertainty for that case and the case of multi -sample test. The expandeduncertainty f/95 was 20CFU/mL(A;=2) for the former case and the expanded uncertainty UilgXj ) was0.093 (k=2.75) for the latter when the degree of confidence is 95%.

  19. Poda de verano en manzanos Red Delicious : efecto sobre la calidad de la fruta y las hojas de los dardos

    OpenAIRE

    2004-01-01

    En el Alto Valle del Río Negro y Neuquén, Argentina (latitud 38° 55´ Sur) se realizó un estudio en árboles cv. Red Delicious, conducidos en espaldera, de 4 m de altura, distanciamiento de 4 x 3 m y una orientación de la plantación Este - Oeste. Durante diciembre los árboles se podaron, eliminando 2/3 de cada crecimiento del año o fueron dejados sin podar (testigo). En la cosecha, en cada árbol y a ambos lados de la fila se determinaron tres alturas sobre el nivel del suelo (1.0 m, 2.5 m ...

  20. Preferências sobre menus dinamicamente consistentes : o caso incompleto

    OpenAIRE

    Moura, Fernanda Senra de

    2012-01-01

    Kochov (2007) demonstra que preferências incompletas sobre menu de loterias admitem uma representação baseada em um espaço de estados subjetivos único e um conjunto de crenças. Esta é uma generalização da representação de preferências completas sobre menus desenvolvida em Dekel, Lipman, and Rustichini (2001). Quando preferências sobre menus são completas, Riella (2010) mostra que Flexibility Consistency é a versão apropriada de Dynamic Consistency, a propriedade geralmente asso...

  1. Pilas de arena sobre grafos dirigidos y algo de complejidad

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    Carolina Mejía Moreno

    2006-01-01

    Full Text Available En este artículo estudiamos el Modelo de Pilas de Arena sobre grafos dirigidos. El comportamiento del modelo sobre grafos dirigidos es más complejo (en término estrictos que sobre grafos no dirigidos; es por ello que, para muchas de las preguntas centrales de la teoría, no se conoce la respuesta en el caso dirigido. En este artículo se ha sintetizado la teoría para digrafos, se han simplificado algunas pruebas y se concretan algunos resultados relacionados con la complejidad de predicción del autómata.

  2. Abrogation of heat-shock protein (HSP)70 expression induced cell growth inhibition and apoptosis in human androgen-independent prostate cancer cell line PC-3m

    Institute of Scientific and Technical Information of China (English)

    Zhi-GangZhao; Qing-ZhengMa; Chun-XiaoXu

    2004-01-01

    Aim: To investigate the effect of abrogating heat shock protein (HSP) 70 expression by antisense HSP70 oligonucleotides treatment on human androgen-independent prostate cancer cell line PC-3m growth. Methods: PC3m cells were treated with 0-16μmol/L antisense HSP70 oligomers for 0-100 hr. Cell growth inhibition was analyzed using a trypan blue dye exclusion test. Apoptotic cells were detected and confirmed by flow cytometric analysis and DNA fragmentation analysis. The protein expression of HSP70 and bcl-2 affected by antisense HSP70 oligomers were determined using Western blot. Results: Antisense HSP70 oligomer induced apoptosis and then inhibited proliferation of PC-3m cells in a dose- and time-dependent manner. Ladder-like patterns of DNA fragments were observed in PC-3m cells treated with 10μmol/L antisense HSP70 oligomer for 48 hr or 8μtmol/L for 72 hr on agarose gel electrophoresis. Antisense HSP70 oligomer pretreatment enhanced the subsequent induction of apoptosis by heat shock in PC-3m cells. In addition, undetectable HSP70 expression was observed at a concentration of 10μtmol/L antisense HSP70 oligomer treatment for 48 hr or 8μtmol/L for 72 hr in Western blot, which was paralleled by decreased expression levels of anti-apoptotic protein bcl-2. Conclusion: HSP70 antisense oligomer treatment abro-gates the expression of HSP70, which may disrupt HSP70-bcl-2-interactions and further down-regulate bcl-2 expression,in turn inducing apoptosis and inhibiting cell growth in PC-3m cells. (Asian JAndro12004 Dec;6:319-324)

  3. SOBRE UNA NUEVA PROPUESTA DEL PROCESO EVOLUTIVO

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    LUIS ALVARO CADENA MONROY

    2009-01-01

    Full Text Available Se mencionan algunas debilidades de tres propuestas alrededor del proceso de evolución de los organismos: gradualismo, neutralismo y equilibrio puntuado. Aunque dos de ellas hacen referen- cia a tasas de cambio, y la otra (neutralismo se refiere a la ausencia de la selección a nivel mi- croscópico, se toman estas tres propuestas debido a la relevancia que tienen en el contexto de la bibliografía sobre la evolución. Se hace una propuesta en la que se busca integrar estos puntos de vista, resolviendo las debilidades de cada propuesta. Para ello, se sugiere que el proceso evolutivo fundamentalmente tiene dos etapas: en la primera etapa, los organismos crean sus nichos ecoló- gicos. En este período, la iniciativa selectiva es de los organismos (“selección invertida”. Posterior- mente, el proceso puede invertirse, y será el nuevo nicho el que seleccione las variantes de los organismos que se le adaptan (“selección normal”. Este último proceso será posible, solamente si la “selección invertida” puede inscribirse en una tendencia de cambio evolutivo más general. Se discuten dos ejemplos en que se aplica la noción de “selección invertida”: el origen de los cordados y la evolución hacia el Homo sapiens.

  4. Sobre a diversidade de sentidos de comunidade

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    Silva, Rosalina Carvalho da

    2005-01-01

    Full Text Available Nosso objetivo neste trabalho foi realizar algumas reflexões sobre as implicações da expansão do uso do termo comunidade e sua diversidade de sentidos. Pretendemos discutir os usos indiscriminados do termo nem sempre acompanhados da devida reflexão e crítica. A partir das perspectivas da sociologia, saúde e psicologia social identificamos que o termo ainda permanece arraigado aos ideais de comunidades naturais próprios aos períodos do feudalismo e do pós-revolução industrial. Esta concepção pode camuflar formas impositivas de trabalho em muitos dos quais o termo comunidade é empregado praticamente como sinônimo de população-alvo e participação comunitária é vista meramente como freqüência às atividades propostas por profissionais que determinam quem são as comunidades. Comprometem-se assim, as práticas emancipatórias. Para repensarmos comunidades, hoje, consideramos necessário relevar os aspectos processuais relacionais, dialógicos e identitários em constantes mudanças. Assim, a condição de comunidade extrapola a delimitação geográfica para as possibilidades de pertencimento e participação através dos espaços simbolicamente delimitados

  5. Intervenciones espectrales (o variaciones sobre el asedio

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    Leticia Katzer

    2013-01-01

    Full Text Available La deconstrucción ha dominado parte importante del pensamiento político y ha producido una revitalización dentro de la epistemología. Este artículo pretende identificar dos conceptos clave en la relación sujeto/alteridad, a saber, «fantasma» y «espectro» con el objeto de repensar el rol de la ontología en una dimensión crucial de las políticas moderno/coloniales. Así, postulamos brevemente las formulaciones fantasmáticas que acechan en la colonialidad para lo cual discurrimos sobre la escritura etnográfica y la escritura fanoniana anticolonial, en una conversación amigable con algunos textos de Derrida. Creemos que la espectrología en ciernes abre una nueva perspectiva para leer las relaciones interculturales en el mundo moderno en clave de conflicto y de agencia.

  6. NOTAS SOBRE A IRRACIONALIDADE DA GUERRA

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    Edilene Leal

    2014-08-01

    Full Text Available Nesse artigo, procedemos a uma análise sobre a irracionalidade da guerra em tempos cada vez mais caracterizados pela evolução da racionalidade técnica, ou seja, em tempos contemporâneos. Esse é o ponto a partir do qual traçamos, aqui, um percurso argumentativo dividido em duas partes. Na primeira, reconstituímos elementos da concepção de guerra de filósofos como Maquiavel, Clausewitz e Kant, destacando, nos dois primeiros pensadores, a prerrogativa de que a guerra é racional quando se configura meio para fins políticos. Na segunda parte, confrontamos essa racionalidade política da guerra com a dupla dimensão técnica que a guerra assumiu: de um lado, a guerra como um fim em si mesmo e não mais como meio da ação política; de outro, a dimensão racionalizante da guerra como resultado do progresso técnico e científico, atualizada como guerra do terror.

  7. Consideraciones sobre de la ética

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    Enrique Cantolla Bernal

    2005-12-01

    Full Text Available El presente ensayo muestra como el hombre, a través de la historia, a estado constantemente buscando beneficios para su vida y ha debido cumplir con varias tareas, que con el tiempo han dado origen a costumbres y comportamientos que han llevado a constituir la moral y la ética. Esta última, nos permite definir y determinar los principales fines de la vida del hombre y cuales son los principios y normas que lo rigen. Así, el estudio de la ética nos plantea la interrogante sobre "los fines de la vida en este mundo" y cuales son las conductas para conseguirlos. Sin embargo, el autor plantea que el hombre se enfrenta a la elección de valores alternativos y ante la interrogante de ¿cuál es el sumo bien del ser humano y de la sociedad?, han surgido diversas teorías que muestran como, casi todas las sociedades, han elegido la búsqueda de la felicidad como "el sumo bien", pero este concepto de "la felicidad" ha variando producto de las diversas teorías y doctrinas, que han emergido a lo largo de su historia.

  8. Apuntes sobre el Cultivo del Cacao

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    Chavarriaga. Eduardo

    1940-09-01

    Full Text Available El sombrío constituye uno de los problemas que se presentan en el cultivo del cacao, de necesaria resolución para ayuda del agricultor en su labor al producir tan importante grano. Contribuye a la economía del cultivo un conocimiento amplio de la cuestión que debe preocupar al productor inquiriendo no solamente por lo acostumbrado en la región, sino por lo que en otras partes se conoce sobre el particular, para abandonar un poco el emperismo y hacer una industria cada día más próspera. Como razón a favor del sombrío, tenemos los países en donde se produce cacao de fina calidad; Trinidad, Venezuela. Nicaragua, siempre acostumbran la sombra; y sin ir muy lejos, en el Valle del Cauca, donde no se cultiva a pleno sol y se obtienen plantaciones de larga duración y producto superior, es bien conocido el beneficio de ella; allí, los agricultores conocen los desastrosos efectos que ocasiona la falta de sombra, cuando por cualquier causa mueren los árboles que la suministran. Por tanto, en este estudio indicaremos el uso de la sombra para el cacao, como el medio de conservar la fertilidad y buenas condiciones del suelo, obtener buenos rendimientos y asegurar larga vida a la plantación.

  9. Sobre a "conveniência" da escola

    Directory of Open Access Journals (Sweden)

    Marisa Vorraber Costa

    2009-01-01

    Full Text Available El artículo pretende mostrar un nuevo "uso" para la escuela, vinculado a la lógica de la etapa actual de la globalización en la que la cultura ocupa una posición singularmente importante, entrelazándose en la vida social, en los circuitos económicos y en los regímenes políticos. Recurriendo a la teorización de George Yúdice sobre los usos de la cultura en la era global, se analizan tres proyectos sociales - Você Apita, Tim Música nas Escolas y Escola Aberta - considerados expresivos de la forma como empresas, organizaciones públicas e iniciativas de la sociedad civil se articulan con la cultura y con la educación para hacer con que los mercados globalizados se muevan, pero no sólo en sus propios intereses, aunque ellos persistan en la cima de las prioridades. Hay indicios de que la "conveniencia" de la escuela sobrepasa el interés mercantil inmediato, y se proyecta como estrategia dirigida hacia una variada gama de propósitos socio-políticos, económicos y culturales. Entre ellos, la posibilidad de gobernar la vida de las personas, forjando visiones de mundo y de sociedad.

  10. sobre la población

    Directory of Open Access Journals (Sweden)

    Mauricio Schoijet

    2005-01-01

    Full Text Available En este artículo se analizan varios elementos de la obra de Thomas Malthus sobre población, en particular la recepción de su teoría y su posición política. Se resumen las críticas políticas, ideológicas y científicas que ha recibido, y se examinan asuntos hasta ahora no tratados por otros comentaristas, como es el caso de las excepciones admitidas por Malthus respecto al papel de las relaciones sociales feudales en la agricultura de Polonia y Rusia. Se sugiere que pese a que su teoría tendía a reforzar la pesada represión social y sexual existente, Malthus no fue apoyado por la burguesía británica (contrariamente a la apreciación de Marx. Se deduce que Malthus no percibió cabalmente los avances de la agricultura, y se refuta la tesis de Donald Winch de que habría sido un liberal de izquierda en política pues si bien en algunos aspectos se le puede considerar progresista, en otros, esenciales, conservador extremadamente represivo o protofascista, incluso precursor de la teoría de los golpes de Estado.

  11. Considerações sobre Agamben

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    Luiz Hebeche

    2012-12-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2012v11n3p329Giorgio Agamben em pequenos artigos, entrevistas e baixo-assinados tem chamado a atenção para o estado de abandono do povo palestino, mas curiosamente esse assunto não é tratado em suas obras mais importantes. Em Homo sacer, por exemplo, ele retoma o termo “muçulmano”, comumente empregado pelos prisioneiros dos campos de concentração como a expressão do maior abandono possível da existência humana, mas não reflete suficientemente sobre a origem dessa palavra, isto é, de que nessa expressão já se encontrava o ódio e o desprezo do sionismo, não só entre os próprios prisioneiros, mas pelo povo palestino e pelos árabes em geral. A seguir comentaremos brevemente algumas obras desse autor que, dando continuidade à ideologia da vitimação, faz com que, mais uma vez, o passado inominável acabe encobrindo o presente abominável.

  12. Puente sobre el Rin Dusseldorf, Alemania Federal

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    Modemann, H. J.

    1980-05-01

    Full Text Available The bridge over the Rhine, in Dusseldorf- Flehe — one of whose most important jobs is to alleviate traffic from the other bridges in the town of Dusseldorf — consists of three clearly diferentiated parts: — a metal part 368 m. in length; — another in prestressed concrete, 780 m. long, and — an A-shape pylon, acting as element joining both. This bridge has the span clearance record in West Germany, and its metal part constitutes the longest corbel in the world.

    El puente sobre el Rin, en Düsseldorf- Flehe —una de cuyas funciones más Importantes es la de aliviar el tráfico a los demás puentes existentes en la ciudad de Dusseldorf—, consta de tres partes claramente diferenciadas: — una metálica de 368 m de longitud; — otra de hormigón pretensado de 780 m de largo, y — un pilono, en forma de A, que sirve como elemento de unión entre ambas. Este puente ostenta el récord de luz libre en la República Federal Alemana, y su parte metálica constituye el voladizo de mayor longitud del mundo.

  13. Cassirer e Sartre sobre o esclarecimento

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    Vinicius de Figueiredo

    2005-12-01

    Full Text Available O presente ensaio levanta alguns aspectos da estética no século XVIII. Partindo da apresentação de duas interpretações hoje clássicas sobre o assunto (a de Cassirer e a de Sartre, busca rever o pressuposto analítico comum a ambas, para, em seguida, apontar as conseqüências que a relação entre autor e público trazem para a compreensão de aspectos estilísticos que nos parecem centrais para a literatura do Esclarecimento.This paper aims at throwing some light on the Eighteenth-Century aesthetics. After examining two classical interpretations - Cassirer e Sartre's - concerning this subject, I argue that both authors share a common analytical pressupposition. My main purpose is to show that without taking account of the the relationship between author and public, we cannot understand some essential characteristics of the literature in the Enlightenment.

  14. Representaciones sociales sobre riesgo y vulnerabiidad

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    Pedro Humberto Faria CAMPOS

    2012-08-01

    Full Text Available O artigo traz uma reflexão teórica sobre a importância da Teoria das Representações Sociais para explicar fenômenos sociais na área da saúde e seu papel metodológico na compreensão de comportamentos e práticas relacionadas ao campo da saúde assim como o potencial transformador das representações para prevenção e o cuidado com a saúde das coletividades humanas. Revisitando os conceitos de práticas sociais e analisando o papel normativo que designa as representações sociais, se discute a mudança social e os fatores sócio-cognitivos a ela associados. Do ponto de vista heurístico destaca a necessidade de identificar a estrutura de uma representação, condição essencial para a comparabilidade.

  15. Roles of vimentin and 14-3-3 zeta/delta in the inhibitory effects of heparin on PC-3M cell proliferation and B16-F10-luc-G5 cells metastasis

    Institute of Scientific and Technical Information of China (English)

    Yah PAN; Xue-jun LI; Li-jun ZHONG; Hong ZHOU; Xin WANG; Kui CHEN; Hao-peng YANG; Yilixiati XIAOKAITI; Aikebaier MAIMAITI; Ling JIANG

    2012-01-01

    Aim:To investigate the inhibitory effects of heparin on PC-3M cells proliferation in vitro and B16-F10-luc-G5 cells metastasis in Balb/c nude mice and identify the protein expression patterns to elucidate the action mechanism of heparin.Methods:Human prostate cancer PC-3M cells were incubated with heparin 0.5 to 125 μg/mL for 24 h.The proliferation of PC-3M ceils was assessed by MTS assay.BrdU incoporation and Ki67 expression were detected using a high content screening (HCS) assay.The cell cycle and apoptosis of PC-3M cells were tested by flow cytometry.B16-F10-luc-G5 cardinoma cells were injected into the lateral tail vein of 6-week old male Balb/c nude mice and heparin 30 mg/kg was administered iv 30 min before and 24 h after injection.The metasis of B16-F10-luc-G5 cells was detected by bioluminescence assay.Activated partial thromboplastin time (APTT) and hemorheological parameters were measured on d 14 after injection of B16-F10-luc-G5 carcinoma cells in Balb/c mice.The global protein changes in PC-3M cells and frozen lung tissues from mice burdened with B16-F10-luc-G5 cells were determined by 2-dimensional gel electrophoresis and image analysis.The protein expression of vimentin and 14-3-3 zeta/delta was measured by Western blot.The mRNA transcription of vimentin,transforming growth factor (TGF)-β,E-cadherin,and αv-integrin was measured by RT-PCR.Results:Heparin 25 and 125 μg/mL significantly inhibited the proliferation,arrested the cells in G1 phase,and suppressed BrdU incorporation and Ki67 expression in PC-3M cells compared with the model group.But it had no significant effect on apoptosis of PC-3M cells.Heparin 30 mg/kg markedly inhibits the metastasis of B16-F10-luc-G5 cells on day 8.Additionally,heparin administration maintained relatively normal red blood hematocrit but had no influence on APTT in nude mice burdened with B16-F10-luc-G5 cells.Thirty of down-regulated protein spots were identified after heparin treatment,many of which are related to

  16. Efectos de la migracion sobre el trabajo infantil en Colombia

    National Research Council Canada - National Science Library

    Khoudour-Casteras, David

    2009-01-01

    El proposito de este articulo es mostrar que el fuerte incremento del desplazamiento interno y de la migracion internacional en Colombia durante los ultimos anos ha tenido repercusiones sobre el trabajo infantil...

  17. Ação da melatonina sobre a dinâmica sanguínea de ratas prenhes e sobre a histogênese do baço e do timo da prole

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    A.C.C. Araújo

    2013-04-01

    Full Text Available Investigou-se a influência da melatonina sobre o hemograma de ratas prenhes e dos filhotes e sobre a histogênese e morfometria do baço e do timo dos filhotes. A melatonina foi administrada na dose 0,5mg/kg de peso corporal, dissolvida em 0,1mL de etanol e diluída em 0,3mL de solução salina. Para análise do hematócrito, contagem total de hemácias e contagem total e diferencial dos leucócitos, amostras de sangue foram coletadas no sétimo, 14ºe 21ºdias de prenhez e aos 10 dias de nascimento dos filhotes. Cortes histológicos do baço e do timo da prole foram utilizados para histoquímica e morfometria. A ausência da melatonina promoveu alterações no hemograma apenas no terço final da gestação, sem interferir no hemograma dos filhotes, e induziu modificações morfológicas e morfométricas no timo e no baço nos primeiros dias de vida dos filhotes. Concluiu-se que a melatonina materna é importante para a modulação do hemograma em ratas prenhes e para o desenvolvimento normal do baço e do timo dos filhotes.

  18. Liberalismo versus republicanismo: notas sobre o conceito de liberdade.

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    Felipe Nunes

    2007-01-01

    Full Text Available Este artigo tem como objetivo contrastar as perspectivas liberal e republicana sobre o conceito de liberdade. Através da comparação feita entre os dois modelos tecemos considerações sobre a realidade brasileira tendo como foco o atual estado de crises advindas dos casos de corrupção no país.

  19. Sobre manhãs, humor e atos de fala

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    Joana Plaza PINTO

    Full Text Available RESUMO Este ensaio apresenta uma trajetória de leituras de Frege a Austin, intermediadas pela interpretação independente e ousada de Kanavillil Rajagopalan. Ao argumentar sobre uma gama de aproximações teóricas entre Frege e Austin, este ensaio narra a importância da interpretação de Rajagopalan para o debate sobre Austin no Brasil.

  20. Recursos sobre emergencias y ayuda humanitaria en internet.

    OpenAIRE

    López Miguel, Daniel

    2007-01-01

    Dada la enorme cantidad de organismos, agentes y personas que llegan a participar en las emergencias, la información y documentación es muy dispersa y diversa, desde organismos oficiales y gubernamentales hasta servicios de noticias, pasando, por supuesto, por organizaciones no gubernamentales. Con el presente artículo pretendemos aportar unas pinceladas sobre los recursos que pueden encontrarse en Internet sobre los conflictos y crisis humanitarias. Peer Reviewed

  1. Bibliografía comentada sobre la historia de Guanacaste

    OpenAIRE

    Solano-Muñoz, Edgar

    2010-01-01

    El texto presenta una bibliografía comentada relacionada con Guanacaste. El propósito del texto es hacer una valoración desde la óptica de la historia regional sobre los textos escritos sobre historia de Guanacaste considerando cuatro aspectos: 1. representaciones sociales, 2. estudios coloniales, 3. historia regional y 4. historia local. Universidad de Costa Rica- Sede Guanacaste

  2. Reflexiones sobre Enfermería

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    Inés Durana Samper

    1992-12-01

    Full Text Available

    agosto 6 de 1992

    Presentación ante la Academia Nacional de Medicina
    Señores miembros de la Junta Directiva, académicos, enfermeras, señores, señoras:

    Introducción
    Para ingresar como Miembro Asociado de esta ilustre Academia Nacional de Medicina, quiero exponer algunas reflexiones sobre la evolución en Colombia de la enfermería, mi profesión, ejercida ininterrumpidamente en estos últimos cuarenta años. Amanera de colofón, me referiré a la función esencial de la enfermera, es decir a su consagración al arte de cuidar.

    La metodología aplicada en este trabajo incluye la revisión de archivos, la lectura de publicaciones y, además, algunas entrevistas con personas que pacientemente escucharon mis preguntas y ampliaron mi información con valiosos comentarios.

    Mis agradecimientos van, en primer término, al académico Fernando Serpa Flórez, quien ha tenido la iniciativa de presentarme a la Academia Nacional de Medicina; también va para aquellos académicos que respaldaron mi aceptación en esta prestigiosa sociedad científica. Igualmente expreso mi reconocimiento al académico Héctor Pedraza Mendoza, autor del primer libro conocido sobre reseña histórica de la enfermería en el país, y a quien correspondió, como funcionario de la administración pública, la orientación y control de la profesión en su cargo de Jefe de la División Infantil y Materna del entonces Ministerio de Trabajo, Higiene y Previsión Social. Libro citado con frecuencia’ durante el trabajo.

    Mis agradecimientos también a mis profesores, y entre ellos, en especial, al académico Alberto Albornoz- Plata. No puedo pasar por alto la memoria de los siempre recordados, doctores Jorge Boshell Manrique y José Pablo Leyva, quienes, desde la Escuela Superior de Higiene, supieron orientarme en la transformación académica del

  3. PROTOCOLO DE KYOTO: DEBATE SOBRE AMBIENTE Y DESARROLLO EN LAS DISCUSIONES SOBRE CAMBIO CLIMÁTICO

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    Rodríguez S. Liliana

    2008-07-01

    Full Text Available El comportamiento climático del planeta y sus consecuencias han propiciado debates sobre los modelos de desarrollo de los países responsables del deterioro acelerado del ambiente y de los fenómenos naturales por estos días recurrentes. Sin embargo, países como Estados Unidos, luego de firmar compromisos como la Convención sobre Cambio Climático, rehúsan adquirir las obligaciones del Protocolo de Kyoto, por temor a sufrir deterioro en sus economías. En este escenario, donde la nación responsable de la emisión de aproximadamente 36% de los gases efecto invernadero resultado de la acción humana en el planeta no se compromete a adoptar políticas restrictivas tendientes a hacer sus modelos de producción más amigables con la naturaleza a pesar de que dichas medidas empiezan a ser impuestas a otras naciones como condicionantes en las negociaciones comerciales internacionales, parece ser que la adopción del Protocolo de Kyoto para países en desarrollo como Colombia no es del todo benéfica.

  4. Caminando sobre huevos: Una reflexión construccionista sobre la investigación

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    Mary Jane Spink

    2006-05-01

    Full Text Available ¿Cuál es la noción de acción que guía a la investigación construccionista? Tomando esta pregunta como base, se recurre a una investigación realizada para evaluar el papel de la Comisión Nacional de SIDA (CNAIDS del Ministerio de Salud de Brasil como punto de partida para formular un concepto de acción compatible con la postura construccionista. Se comienza problematizando la noción clásica de acción, pasando a continuación a proponer alternativas, explorando las implicaciones de nociones tales como la de en-acción, discutida por Varela, para la investigación construccionista. La investigación sobre la CNAIDS se usa como ejemplo de las maneras posibles de conducir la investigación-intervención. La expresión investigación-intervención se usa en este artículo como estrategia discursiva para enfatizar que toda investigación tiene consecuencias, siendo necesariamente un proceso de producción de sentidos sobre los actos de nuestras vidas.

  5. Oxide fluoride sulfides of the lanthanoids with the formula M{sub 6}O{sub 2}F{sub 8}S{sub 3} (M = La-Nd, Sm, Gd); Oxidfluoridsulfide der Lanthanoide vom Formeltyp M{sub 6}O{sub 2}F{sub 8}S{sub 3} (M = La-Nd, Sm, Gd)

    Energy Technology Data Exchange (ETDEWEB)

    Grossholz, Hagen; Zimmermann, Dirk D.; Janka, Oliver; Schleid, Thomas [Stuttgart Univ. (Germany). Inst. fuer Anorganische Chemie

    2013-07-15

    The lanthanoid(III) oxide fluoride sulfides M{sub 6}O{sub 2}F{sub 8}S{sub 3} (M = La-Nd, Sm, Gd) can be obtained by reacting the rare-earth metals, their trifluorides and sesquioxides with elemental sulfur in appropriate molar ratios at 850 C flux-assisted by NaCl in gas-tightly sealed niobium or tantalum ampoules. All compounds are colorless, except for those containing M = Pr with green, M = Nd with lilac and M = Sm with yellow color. They form transparent single crystals as needles or rods. The M{sub 6}O{sub 2}F{sub 8}S{sub 3} representatives crystallize in a hexagonal structure (space group: P6{sub 3}/m; a {approx} 1382-1326, c {approx} 398-376 pm, c/a {approx} 0.288-0.284; Z = 2) with two different crystallographic M{sup 3+} positions. The (M2){sup 3+} cations reside in ninefold coordination of anions arranged as tricapped trigonal prisms formed by three F{sup -}, four mixed-occupied O{sup 2-}/F{sup -} and two S{sup 2-} anions, resembling the unique M{sup 3+} coordination sphere of the M{sub 3}OF{sub 5}S-type oxide fluoride sulfides. The (M1){sup 3+} cations are surrounded by square antiprisms built of four O{sup 2-}/F{sup -} and S{sup 2-} anions each, which are capped by one F{sup -} anion each, again resulting in a ninefold coordination similar to that of the A-MFS-type fluoride sulfides. While the crystallographically unique S{sup 2-} anions have six cationic neighbors arranged in trigonal prisms, there are four different light-anion positions. Two of them, representing only fluoride anions, are situated in a triangular environment of cations ((F1){sup -}: planar, (F2){sup -}: non-planar). The mixed-occupied light-anion positions (F3){sup -}/(O3){sup 2-} and (F4){sup -}/(O4){sup 2-} exhibit tetrahedral coordination spheres with a ratio F{sup -}: O{sup 2-} = 2:1. The M{sub 6}O{sub 2}F{sub 8}S{sub 3} arrangement is characterized by an empty hexagonal channel structure created by (F1){sup -} anions with a potential of accommodating alkali-metal cations like Na

  6. Reflexión sobre Rubem Fonseca

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    Marco Martos Carrera

    2011-05-01

    Full Text Available El día de hoy la Universidad Nacional Mayor de San Marcos honra a sustradiciones recibiendo a Rubem Fonseca, el representante más conspicuode la cultura del Brasil contemporáneo, y haciéndolo rinde homenaje a supaís originario y a la lengua portuguesa hermana de la española que esla lengua franca en nuestra nación. Expresa también el deseo evidente denuestra Facultad de Letras y Ciencias Humanas de abordar la Literatura deBrasil como parte sustancial de la Literatura Latinoamericana y no comoalgo ajeno, pero vecino, cuando decimos profesar un interés por la LiteraturaHispanamericana.Dos cuestiones de fondo en el estudio de la obra de un escritor tienensuma importancia: la cultura en la que se forma y otra, su propia biografía.La cultura del Brasil, sobre todo en el plano literario se formó en vínculo estrechocon la cultura de Portugal, pero pronto la tierra americana, las gentesnacidas aquí fueron dejando su impronta en eso nuevo que nacía y que estádejando honda huella en la cultura universal. En ese sentido un narradorcomo Machado de Assís, aludido irónicamente por uno de los personajesde los cuentos recientes de Rubem Fonseca, es en el siglo XIX, la mejor manifestaciónde talento literario de América del Sur. Su nombre se pronunciacon respeto al lado de otros grandes escritores de diferentes latitudes queson los fundadores del cuento contemporáneo: Poe, Chejov, Maupassant.

  7. Perspectivas sobre la comunicación

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    María Luisa Naranjo Pereira

    2005-01-01

    Full Text Available Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la relación humana y en las etapas donde se desarrolla. A partir de la comunicación pragmática, se analizan los axiomas comunicacionales en que se fundamenta y lo que se conoce como patologías de esos axiomas. Además se revisan las principales características que distinguen la asertividad en la comunicación y las distintas formas de manipulación que la entorpecen. Del enfoque de Virginia Satir, se presentan los diversos aspectos de la comunicación, tanto funcional como disfuncional y los modelos de comunicación propuestos por esta autora. Se revisan aspectos importantes del enfoque de la comunicación educativa, tales como el control de la distancia, la voz y el cuerpo, las palabras y el situacional; así como los elementos que bloquean el proceso de comunicación y las sugerencias acerca de formas correctas de escuchar. Además, se hace referencia a la necesidad de emplear procesos educativos más holísticos y constructivistas y una comunicación-interrelación horizontal y con equidad.

  8. Sobre el genio de las mujeres

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    Valcárcel, Amelia

    1992-11-01

    Full Text Available Not available.

    A los varones, desde Tácito a Schopenhauer, nunca les ha parecido que las verdaderas mujeres son las que tienen en casa, sino las que tienen los otros varones (los germanos, los orientales. Por su parte, Wojtyla ha hecho profesión de fe «en el genio de las mujeres», reclutando enternecidos agradecimientos como el de Macciochi. La autora del presente artículo adopta una perspectiva histórica y una actitud analítica para aclarar qué es ese genio que como genérico nos adjudican. En primer lugar, la idea de genio es romántica y va emparejada con la de destino, sobre todo en el caso de los genios colectivos. Se trata de nociones que se construyen estipulativamente con fines pragmáticos y no admiten, por definición, contraejemplos. En el caso del genio de las mujeres, los llamados «valores femeninos» que lo constituyen pertenecen al ámbito de la Siulichkeit, y su eventual convalidación en el de la Moralitiit no puede obviar el proceso consistente en la crítica y el desmarcarse de una Sittlichkeit adjudicada como estereotipia que se contrasta, no con otra estereotipia simétrica, sino con lo universal, que se solapa con el genérico masculino. La autora, por último, nos recuerda que la fabricación de este genio que, a título de colectivo, se nos atribuye a las mujeres tiene lugar a costa de la usurpación de nuestra individualidad y de la ausencia de esquemas pragmáticos de reconocimiento de la genialidad individual que pueda producirse en el genérico femenino. Ahora bien: es esta última la que las mujeres necesitamos para poder romper con las tradiciones establecidas e instituir nuevos relatos.

  9. Sobre o Classicismo de Goethe (Caracter

    Directory of Open Access Journals (Sweden)

    Júlio César Mioto

    2009-10-01

    Full Text Available Este artigo mostra certo descompasso entre as orientações positivas da estética de Goethe, como aparecem nos seus Escritos sobre arte, e a realização efetiva de sua obra artística, tomando o caso exemplar de Ifigênia em Táuris. Tal ocorre, conforme sustentamos, por uma exigência interna à obra, que de algum modo já era compreendida por sua estética anterior. Pelo tratamento do problema clássico do “caracter”, veremos como se realiza sua concepção do procedimento maneira. Também como se dá uma superação em relação às prescrições clássicas por meio de uma particular resolução do drama.

  10. Considerações sobre o Mercosul

    Directory of Open Access Journals (Sweden)

    Ricardo Seitenfus

    1992-12-01

    Full Text Available Após traçar as origens históricas e conjunturais do processo de integração na Bacia do Prata, o autor analisa as características do Tratado de Assunção, através de um organograma detalhado. Na segunda parte, três questões sem resposta são colocadas aos leitores, ou seja, o processo de institucionalização envolvendo a constituição de um espaço supranacional que estará diretamente vinculado aos objetivos do processo; as relações do Mercosul com o Nafta e a definição de um quadro de cooperação e, finalmente, coloca a questão sobre o nível de participação do Estado no processo integracionista sob a ótica da necessidade de reconversão de certos setores econômicosIn the first part of this article, the author, after delineating the historical and circumstancial sources regarding the process of integration in the Prata Basin, analyses the characteristics of the Traty of Asunción (Paraguay through a detailed organizational chart. In the second part, three open questions are discussed: (a the process of institutionalization which involves the constitution of some supranationalization which invoves the constitution of some supranational space which will be closely related to the objectives of the process; (b the relationships between the Mercosul and the Nafta and the definition of a cooperative program; (c the level of participation of the State into the integrationist process under the dear need of a reconversion of some economic sectors.

  11. Estudio sobre encofrados de madera modernos

    Directory of Open Access Journals (Sweden)

    de la Peña Aznar, Juan M.

    1980-12-01

    Full Text Available The author continues the development of the subject «Modern Timber Formwork», by summing up the comparative examination —already carried out in Part III of this Study— of the different types of glued timber existing on the market. In addition, the loads and stresses allovk/able for coniferous timber and the proposal for establishing Regulations for the Timber Section of the Research and Experimental Forestry Institute of Spain are given. In part V of the author's Study, published in this article, the important subject of the glues used for joining timber, a truly vital point in order to obtain louvered timber beams which are simply glued together, is approached.

    El autor continúa el desarrollo del tema sobre «Encofrados de madera modernos», resumiendo el estudio comparativo —ya hecho en la Parte III de este Estudio— de las diferentes vigas de madera encolada existentes en el mercado dando, además, las cargas y tensiones admisibles para maderas coníferas y la propuesta de Reglamentación de la Sección de Maderas del Instituto Forestal de Investigaciones y Experiencias de España. En la parte V del Estudio del autor, publicada en este artículo, se aborda el importante tema de las colas empleadas para las uniones de madera, algo realmente vital para la obtención de vigas de madera en celosía simplemente encoladas.

  12. Construcciones en yeso proyectado sobre vegetales

    Directory of Open Access Journals (Sweden)

    Martínez, Hubert

    1986-07-01

    Full Text Available A construction method developed in early 1981 in Senegal, whose main objective is the evaluation of natural and human sources, specially those of wild vegetables and the phosphogypsum (a waste of chemical industry in Senegal. The introduction of the mechanical projection allows a noticeably growth in work performances and an improvement of the quality. The projection reduces de number of trades intervening in the work, doing away with plasters, watertightness systems and paintings, and simplifying the setting of technical installations and of carpentry. The acquisition of this projecting material is not very expensive, so, it is easy for small and medium enterprises to reach an expertness in gypsum work. Its finantial rentability is assured for a prize of the gypsum of 180% of the prize of the cement.Procedimiento de construcción desarrollado al comienzo de 1981 en el Senegal, teniendo como objetivo la valoración de las fuentes naturales y humanas, especialmente los vegetales en estado silvestre y el fosfoyeso, residuo de la industria química del Senegal. La introducción de la proyección mecánica permite aumentar sensiblemente el rendimiento del trabajo y mejorar la calidad. La proyección reduce el número de oficios que intervienen en la obra por la supresión de enlucidos, sistemas de estanquidad y pinturas sobre la gruesa obra y simplifica la colocación de las instalaciones técnicas y de carpintería. La adquisición del material de proyección, necesitando un capital relativamente modesto, se encuentra al alcance de pequeñas y medianas empresas que deseen especializarse en los trabajos de yeso. La rentabilidad financiera del procedimiento está asegurada para un precio del yeso de hasta el 180% del precio del cemento.

  13. Sobre el concepto de campo en Bourdieu

    Directory of Open Access Journals (Sweden)

    Guillermo Bustamante Zamudio

    2016-01-01

    Full Text Available Con el concepto de tensión, Pierre Bourdieu da la herramienta clave para distinguir el campo de la ciencia y el campo en el que se lucha por la legitimidad de la ciencia (en el seno del mundo de la ciencia. Así mismo, su concepto de presión es clave para entender la relación entre la sociedad y la ciencia, la lucha por la legitimidad de la ciencia en el mundo social (tres autores han desarrollado tales tópicos: Gaston Bachelard, el primero, de orden epistemológico; Bourdieu mismo, el segundo, de orden sociológico; y Jean-François Lyotard, el tercero, de orden político. Sin embargo, Bourdieu oscila entre diferenciar y mezclar, tanto las tensiones de cada uno de los campos mencionados, como la oposición entre tensión y presión. Por otro lado, Bourdieu nos permite pensar algunos de los efectos propios de la presión ejercida sobre la ciencia por los financiadores, la industria, el Estado y el público: la cienciometría, que deja como resto una alodoxia; las asociaciones y las instituciones, que producen como resto una pérdida de dedicación a la investigación que busca conocer; y una vulgarización que deja como resto una descontextualización y una reproducción del sistema dominante. Con el interés de sostener el trabajo de investigación que hacemos, usando, entre otros recursos el concepto de campo, postulado por Pierre Bourdieu, leímos de forma pormenorizada su texto El oficio de científico. Ciencia de la ciencia y reflexividad [2000-1].

  14. Reflexiones sobre las estrategias de desarrollo

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    Alberto Ortíz Gómez

    1991-05-01

    Full Text Available RESUMEN La apertura constituye actualmente el tema que mayor atención genera en los diversos círculos donde se debate si la condición  económica de la nación debe descansar en el modelo de sustitución de importaciones, debe residir en el fortalecimiento  de las exportaciones menores o debe definitivamente sustentarse en esfuerzos  integrados del aparato  gubernamental, el sistema financiero y la clase empresarial. Nadie discute la importancia de avanzar en pos de la actualización tecnológica, el incremento de los coeficientes de productividad, el mejoramiento de los niveles de calidad y la consecuente  intromisión de nuestra producción en los mercados internacionales. Frente a la necesidad de eliminar atávicas costumbres relacionadas con el pensar actuar en pequeño, vivir el pasado, aprovechar situaciones monopólicas de mercado y usufructuar el proteccionismo gubernamental, el remezón constitucional y la apertura en todos los órdenes de la vida nacional deben apuntar a un desarrollo de que participe de la colectividad en su conjunto. Sin embargo, en el convencimiento en las ventajas que plantean el nuevo esquema de desarrollo, es claro que existen dudas a espejar  e interrogantes no resueltos sobre la forma como deben articularse las  medidas económicas instauradas alrededor  de un proceso de apertura cuyos resultados no pueden analizarse con el criterio miope de quienes todo lo juzgan con base en la inmediatez.

  15. Puente sobre el Rhin – Suiza

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    Bänziger, D. J.

    1972-10-01

    Full Text Available In the brief period of two months a new bridge over the Rhine has been constructed to substitute one which collapsed on August 1970, because of the undermining of one of its pillars. On November 28 1970 the new bridge was opened to the traffic, including trucks of up to 3.5 Kp, and on December 7th of the same year vehicles of up to 26 Kp could use it. In the construction of this bridge, for the first time, use has been made of cylindrical, prefabricated, precast thin shells. This project is of special significance because of its operational importance, since it connects Lichtenstein and Switzerland; the exceptionally short time of its construction; and the new type of deck used.Para sustituir un puente sobre el Rhin, hundido el 14 de agosto de 1970 por socavación de uno de sus pilares, se ha construido un nuevo puente en el escaso plazo de dos meses. El 28 de noviembre de 1970, este nuevo puente se abrió al tráfico de vehículos de hasta 3,5 Mp, y el 7 de diciembre del mismo año, a los vehículos de hasta 26 Mp. En la construcción de este puente se han utilizado, por vez primera, láminas cilíndricas de cubierta, prefabricadas y pretensadas. La importancia del puente, que sirve para el enlace entre el Principado de Liechtenstein y Suiza, el nuevo tipo de tablero utilizado, así como el plazo de construcción, extraordinariamente breve, dan un interés especial a esta obra.

  16. Sobre el estado evolutivo de β Pictoris

    Science.gov (United States)

    Brunini, A.; Benvenuto, O. G.

    Desde el descubrimiento de fuertes excesos infrarrojos en β Pictoris, esta estrella ha sido muy estudiada y es considerada candidata a poseer un sistema planetario propio. β Pic está rodeada de un disco asimétrico de polvo que se observa de canto y que esta vacío a distancias <= 40 AU. Esto se considera una fuerte evidencia en favor de la presencia de (al menos) un planeta gigante. Recientemente se han observado líneas de material circunestelar que se han interpretado como consecuencia de la caída de objetos cometarios sobre esta estrella. Recientemente se ha utilizado la existencia del disco de polvo para atribuir una edad corta (pre - secuencia principal) a βPic. Sin embargo, la evaporación de estos cometas provee suficiente polvo como para explicar la presencia del disco observado sin necesidad de edades cortas. En este trabajo mostramos que la comparación entre la tasa de impactos cometarios estimada en el Sistema Solar para diferentes etapas de su evolución y los datos observados en β Pic indica edades avanzadas para β Pic. Esta estimación debe tomarse con cautela ya que depende de la estructura de los sistemas planetarios. Además mostramos que, desde el punto de vista de la evolución estelar y con las incertezas presentes en la luminosidad y la temperatura efectiva, existe un continuo de edades posible para β Pic. Sin embargo, empleando los datos provenientes de los flujos cometarios encontramos que una edad prolongada es consistente con ambos tratamientos.

  17. Contando historias sobre contadores de historias

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    Tomás Ibáñez Gracia

    2002-06-01

    Full Text Available Hay personas que nos han dejado como legado un texto. Su texto. A veces, una obra ingente, fecunda, imprescindible. Hay otras que nos han dejado además la palabra, su palabra, su vida. Rex Stainton-Rogers es una persona del segundo tipo. Un ser humano excesivo, brillante, emprendedor, vivo. Su palabra es su herencia. Su legado, algunos y algunas de los más relevantes científicos sociales de la emergente generación, sobre todo en Gran Bretaña, que han sido personas educadas, entrenadas, formadas por esta figura excepcional. Su trabajo, más allá de los textos que nos ha legado, ha consistido especialmente en mostrar la vida, el laboratorio donde se forja realmente el conocimiento. Y así, quienes pudieron compartir una parte de su vida con él, han tenido el privilegio de estar en contacto con todo aquello que hace apasionante el saber, aquello que lo hace útil, aquello que te emborracha de placer. Rex murió en febrero de 1999 del mismo modo en que vivió, libre, espléndido. Un año más tarde, su compañera Wendy Stainton-Rogers organizó junto con algunas de las personas que más deben a la vida de Rex, un simposium para conmemorarle a él, a su vida y a su palabra. Ésta es la contribución que nosotros hicimos a ese homenaje.

  18. Sobre o campo da Psicologia Social

    Directory of Open Access Journals (Sweden)

    Belinda Mandelbaum

    2012-03-01

    Full Text Available O campo da Psicologia Social é apresentado como território fértil, na contemporaneidade, para constituir-se como um laboratório para a produção em Ciências Humanas, uma vez que, no século XX, cada vez mais o social foi em direção ao psicológico. Neste campo, nosso embate dá-se no modo como entendemos o hífen pressuposto na integração psicossocial. A autora propõe que, entre o psicológico e o social, o hífen domina, pois ele é a própria essência relacional que é inerente a cada um dos elementos. Sugere que o modelo para entender o homem e suas circunstâncias proposto por Freud imbrica de forma indissociável o psicológico e o social, a ontogênese e a filogênese, com uma potência que teve impacto sobre todo o campo das Ciências Humanas. A Psicanálise é um instrumento hermenêutico para colaborar na elucidação dos fenômenos sociais. A autora utiliza imagens construídas por Freud e Walter Benjamin e poemas de Carlos Drummond de Andrade para fortalecer o entendimento do hífen psicossocial tanto em sua ação multidimensional quanto em sua organização.

  19. 白光LED用新型红色荧光粉SrMgSi2O6:Eu3+,M(M=Gd3+,Ti4+)的合成及性质%Preparation of New Red Emitting Phosphor SrMgSi2O6:Eu3+,M(M=Gd3+,Ti4+)for White LEDs and Its Properties

    Institute of Scientific and Technical Information of China (English)

    翟永清; 冯仕华; 张张; 石领娟; 郝晓红

    2010-01-01

    以Na2CO3为电荷补偿剂,采用凝胶-燃烧法合成新型红色硅酸盐发光材料SrMgSi2O6:Eu3+.用X射线粉末衍射仪、荧光分光光度计等对合成产物进行分析和表征.结果表明:SrMgSi2O6:Eu3+的晶体结构与Sr2MgSi2O7相同,同属四方晶系.样品nSrMgSi2O6:Eu3+的激发光谱在220~300 nm出现一宽带吸收,归属于O2--Eu3+之间的电荷迁移,300 nm以后出现的锐线峰为Eu3+的f-f跃迁吸收峰,其最强锐线峰位于400 nm,因而,可以被InGaN管芯产生的紫外辐射有效激发.发射光谱由两个强发射峰组成,位于592和618 nm处,分别属于典型的Eu3+的5D0→7F1和5D0→7F2跃迁.此外,研究发现:共掺Gd3+或Ti4+均能敏化Eu3+的发光,可有效提高样品的红光发射.因此,SrMgSi2O6:Eu3+,M(M=Gd3+,Ti4+)有望成为一种与InGaN管芯匹配的白光LED用红色荧光粉.

  20. Estudos sobre a Esquistosomose em Pernambuco, Brasil

    Directory of Open Access Journals (Sweden)

    Aggeu Magalhães

    1940-01-01

    Full Text Available Os autores referem os resultados dos estudos sobre esquistosomose realisados, em Pernambuco, de Novembro de 1938 a Dezembro de 1939. Não se extendem em discussão, nem comentarios, tampouco, relacionam suas verificações com o que já foi relatado sobre o assunto em trabalhos nacionais e estrangeiros, pelo fato de que, não se trata de um resultado definitivo e sim de atividades que irão proseguir. Os estudos sistematicos em torno da endemia esquistosomica foram executados em duas localidades diversas pela população e pela situação geografica e ecologica. Pontezinha é uma povoação de 1200 habitantes localizada proximo a um conjunto de charcos e lagõas de agua dôce onde pululam caramujos do tipo olivaceus de Spix, e apresenta uma taxa de infestação de 21,4% para individuos do sexo masculino, e de 14,7% para os do sexo feminino. A distribuição por grupos de idade mostra que a incidencia cresce até o grupo de 16 a 20 anos de idade, quando atinge a percentagem de 37,8%, para decrescer em seguida. Em Vitoria a incidencia foi maior nos indivíduos do sexo feminino, atingindo a taxa de 41,4%, dando o sexo masculino a taxa de 36,9%. Por idade a percentagem maxima é atingida pelo grupo de 11 a 15 anos. Vitoria é uma cidade de 1500 habitantes, construida á margem do rio Tapacurá, onde se encontram numerosos caramujos do tipo centimetralis Lutz. A divergencia de incidencia corre por conta dos habitos da população e pela utilização que ela faz do rio, sendo maior em Vitoria porque a proximidade do rio facilita o uso de suas aguas para banho e serviços domesticos, condicionando este ultimo fato, a maior infestação das mulheres. O estudo da frequencia da infestação dos caramujos por cercarias de diversos trematodios, permite suspeitar uma relação inversa entre a taxa de infestação e o diametro maximo atingido pelos caramujos, parecendo este fato confirmar os trabalhos de Vianna Martins sobre a identidade dos hospedeiros

  1. Sobre la investigación en arquitectura y urbanismo. IV Jornadas Internacionales sobre Investigación en Arquitectura y Urbanismo.

    OpenAIRE

    Torres Cueco, Jorge

    2012-01-01

    Presentación inaugural de las IV Jornadas Internacionales sobre Investigación en Arquitectura y Urbanismo, a cargo del director de las jornadas, Sr. Jorge Torres Cueco. Torres Cueco, J. (2012). Sobre la investigación en arquitectura y urbanismo. IV Jornadas Internacionales sobre Investigación en Arquitectura y Urbanismo. 4IAU 4ª Jornadas Internacionales sobre Investigación en Arquitectura y Urbanismo. http://hdl.handle.net/10251/15033.

  2. As vicissitudes do "ensaio sobre o dom"

    Directory of Open Access Journals (Sweden)

    Lygia Sigaud

    1999-10-01

    Full Text Available A partir dos anos 60, antropólogos de diferentes tradições nacionais passaram a convergir no sentido de considerar que o texto de Marcel Mauss, "Ensaio sobre o Dom", contivesse uma teoria da troca, que atribui à identificação entre a coisa dada e o espírito do doador o princípio de explicação das transações. Esta interpretação contrasta com a que tiveram os contemporâneos de Mauss, os quais resgataram do trabalho suas dimensões relativas ao direito, às obrigações e às prestações totais. Partindo desta constatação, o artigo problematiza o destino do ensaio e busca torná-lo inteligível. Para tanto examina as condições sociointelectuais que contribuíram para que se produzisse a inflexão na leitura e a consolidação de uma espécie de crença coletiva em relação ao trabalho. Através deste estudo de caso, a autora identifica mecanismos que operam no processo de construção de teorias, na conformação de representações acerca de textos e na sua consagração no âmbito da antropologia.From the 1960s, anthropologists of different national traditions came to share the view that Marcel Mauss’s text, "Essay on the Gift," contained a theory of exchange which takes the identification between the thing given and the spirit of the donor as the explanatory principle of transactions. This interpretation contrasts with that held by Mauss’s contemporaries, who lifted from the work aspects relating to law, obligations and total prestations. Starting from this fact, the article problematizes the essay’s fate and seeks to make it intelligible. To this end, it examines the socio-intellectual conditions which contributed to producing this inflection in the readings of the work and the consolidation of a kind of collective belief concerning it. Through this case study, the author identifies mechanisms which operate in the process of constructing theories, in the conformity found in representations of certain texts, and in the

  3. ESTUDO PROSPECTIVO SOBRE ENCAPSULAMENTO DE COMPOSTOS BIOATIVOS

    Directory of Open Access Journals (Sweden)

    Larissa Assunção

    2014-12-01

    Full Text Available Com o advento da nanotecnologia, houve o desenvolvimento de técnicas envolvendo processamento, fabricação e aplicação de estruturas, com forma e tamanho controlados, sendo que na indústria de alimentos, estas formulações, tanto na faixa micrométrica como nanométrica, vêm sendo utilizadas com o objetivo de favorecer o produto final. Tendo em vista a importância tecnológica dessa técnica e do grande interesse nacional e internacional, principalmente no ramo da indústria alimentícia, sobre os benefícios do encapsulamento, o presente estudo prospectivo teve como objetivo avaliar o panorama mundial relativo ao tema em questão, correlacionando-o com os documentos de patentes depositados. Para tanto, realizou-se uma pesquisa das patentes na base de dados europeia Espacenet®, utilizando os descritores do tema em estudo associados aos códigos de classificação. As informações encontradas foram compiladas em gráficos e discutidas. Pôde-se observar que o maior número de patentes referiu-se ao código A23L1/00 - alimentos ou produtos alimentícios: a sua preparação ou tratamento e houve um crescimento exponencial em relação ao depósito de patentes nos últimos 10 anos, sendo os Estados Unidos o país líder em número de patentes depositadas (60%. A Firmenich e CIE lidera o ranking com mais patentes depositadas. Em relação à área de atuação, predomina a indústria alimentícia (69%. No que diz respeito ao Brasil, o país aparece com apenas 1 patente detentora desta tecnologia, sendo um número bastante reduzido o que mostra a falta de incentivo neste setor. Diante dos resultados obtidos, concluiu-se que, apesar de ser uma tecnologia recente, observa-se uma tendência ao crescimento de depósito de patentes.

  4. Marginalia: algumas notas adicionais sobre o dom

    Directory of Open Access Journals (Sweden)

    Pierre Bourdieu

    1996-10-01

    Full Text Available Prosseguindo a análise do dom, este artigo busca ultrapassar as visões fenomenológica, estruturalista e economicista do fenômeno. Para tanto, desloca o eixo de interrogação na direção do tempo e da incerteza ligados ao intervalo entre o dom e o contradom, do agente e da ação ligados às práticas, da economia de bens simbólicos e o habitus específico que a funda. Demonstrase assim, contra todo reducionismo (à consciência, ao cálculo inconsciente ou ao cálculo propriamente dito, que a razão do dom só pode repousar sobre sua dupla verdade, seu caráter generoso e obrigatório. Por outro lado, demonstrase também que foi somente através de uma revolução simbólica, e não o desenvolvimento de uma suposta natureza humana, que uma economia da troca pôde, historicamente, se destacar da economia do dom, cuja possibilidade continua aberta, dependendo apenas dos investimentos coletivos que sejam efetuados em sua direção.Resuming an analysis of the gift, this article seeks to go beyond the phenomenological, structuralist, and economicist view of this phenomenon. It thereby shifts the trust of questioning towards the time and uncertainty linked with the interval between the gift and the counter-gift, the agent and the action linked to such practices, the economy of symbolic goods, and the specific habitus underlying it. It thus demonstrates against any and all reductionism (to consciousness, to unconcious calculation, and to calculation per se that the gift's reason can only lie in its double truth, its generous and obligatory nature, both disinterested and interested. The author also demonstrates historically that it is only through a symbolic revolution, and not the development of a supposed human nature, that an economy of exchange can stand out from the economy of the gift, whose possibility remains open, requiring collective investments in its direction.

  5. CONSIDERACIONES SOBRE EDUCACION MEDICA y SALUD

    Directory of Open Access Journals (Sweden)

    Jaime Escobar Triana

    1984-11-01

    Full Text Available

    l. Los cambios, las corrientes migratorias internas, transformaron un país de población rural en urbana, al mismo tiempo con un epifenómeno de ruralización de la ciudad. De un 700/0 de población rural se pasó a un 700/0 o más y con tendencia a umentar la población urbana. Esto lleva a un replanteamiento en la atención de la salud. Además, se suma a lo anterior, la información masiva sobre la población que alienta la posibilidad de alcanzar
    tratamientos y drogas maravillosas o recursos extraordinarios como las unidades de cuidados intensivos o los transplantes, para dar dos ejemplos, que motivan al público a demandar dichos servicios. De otra parte, la misma información científica que alcanza
    apabullantes cantidades, solamente permite que el médico logre obtenerla y asimilarla en forma limitada y angustiante para su aplicación práctica.

    2. En la creación de nuevas Escuelas de Medicina deben considerarse entre otros los siguientes hechos o factores, favorables o desfavorables que no sólo afectan a Colombia sino que tienen características universales en algunos de sus aspectos:
    a La demanda de cupos en educación superior, entre ellos la medicina, nunca satisfecha.
    b Las presiones sociales que tienen el estudio como un método de ascenso por prestigio local o regional o político o todos juntos y no por la necesidad de formar más médicos.
    c La inconveniencia de la masificación de la educacación médica que demerita la calidad y por tanto es preferible el crear nuevas escuelas con número limitado de estudiantes que permitan una alta calidad de formación.
    d La dificultad de modificar los curricula tradicionales establecidos que impiden actualizar la docencia a las circunstancias que vive y requiere la salud del país.
    e La politización de las universidades públicas que demeritan la actividad docente al imponerse condiciones extrauniversitarias en la formación y realización de

  6. Reflexiones sobre la anorexia Reflexões sobre a anorexia Reflections about anorexy

    Directory of Open Access Journals (Sweden)

    Andrea Ferrero

    2009-03-01

    Full Text Available El propósito de este artículo es presentar algunas reflexiones sobre el trastorno anoréxico, algunas posibles explicaciones sobre el mismo, y proponer una respuesta posible desde la perspectiva psicoanalítica. Este estudio plantea el sufrimiento del sujeto como la manifestación de una relación inconsciente entre las ecuaciones afectivas y el entramado social de la persona. Se discute la particular relación que se establece entre la necesidad, la demanda y el deseo en este tipo de trastornos, y cómo el síntoma anoréxico se plantea como estrategia enferma de defensa del deseo. Se puede considerar el impacto que la presión de la cultura tiene en la manutención del síntoma anoréxico, dada la importancia del ideal de delgadez y belleza, también asociados con la obtención de mayor éxito y felicidad. Finalmente, se plantea el valor del análisis de la personalidad en relación a aspectos sociales para la consideración del trastorno anoréxico, el cual debe ser comprendido singularmente, más allá de sus manifestaciones y de la posible limitación a la estructura de la histeria.O objetivo deste artigo é apresentar algumas reflexões sobre o processo de adoecimento da anorexia e algumas possíveis explicações sobre esse processo, bem como propor uma possível resposta a partir da perspectiva psicanalítica. Este estudo estabelece o sofrimento do sujeito como a manifestação da relação inconsciente entre as equações afetivas e a trama social da pessoa. Procura-se discutir a peculiar relação entre necessidade, demanda e desejo neste tipo de transtorno, e como a anorexia é uma estratégia patológica de defesa do desejo. Pôde-se observar a influência da pressão da cultura na manutenção da anorexia, justificada pelo ideal de magreza e de beleza, que também são associadas com a possibilidade de obter maior êxito e felicidade. Por último, considera-se o valor da análise da personalidade em relação aos aspectos sociais

  7. Nota sobre Marcel Mauss e o ensaio sobre a dádiva

    Directory of Open Access Journals (Sweden)

    Lanna Marcos

    2000-01-01

    Full Text Available Este artigo analisa a obra clássica de M. Mauss, Ensaio sobre a dádiva, à luz de desenvolvimentos recentes da Antropologia. Salienta como contribuição de Mauss o entendimento da dimensão política da troca de dádivas, assim como a sugestão de sua universalidade, posteriormente demonstrada por Lévi-Strauss, constituir-se em princípio formal-abstrato, e não num fato empírico-concreto. A partir desse princípio, avalia a tese segundo a qual a dádiva é fundamento de toda sociabilidade e comunicação humanas, assim como sua presença e sua diferente institucionalização em várias sociedades analisadas por Mauss, capitalistas e não-capitalistas.

  8. Uma Nota Sobre Efeitos de Gastos Públicos Federais Sobre o Crescimento da Economia Brasileira

    Directory of Open Access Journals (Sweden)

    Soraia Santos da Silva

    2014-12-01

    Full Text Available O artigo tem o objetivo de analisar os efeitos dos gastos governamentais sobre o produto da economia brasileira ao longo do período de 1980 a 2005, identificando a contribuição de algumas categorias de gastos públicos sobre o crescimento do produto no Brasil. Para isso, foram investigadas as séries dos componentes das despesas públicas federais, em particular, tanto por grupo como por função. Os procedimentos metodológicos usados basearam-se nos testes de Dickey-Fuller Aumentado (DFA e Phillips e Perron (PP, teste de Causalidade de Granger e o método de Cointegração de Engle e Granger e Johansen. Os resultados dos testes de raiz unitária mostraram que as séries estudadas de produto e despesas públicas são I(1. A maioria dos pares de variáveis mostrou causalidade no sentido de Granger fluindo dos componentes dos gastos públicos para o produto. As exceções ficaram por conta dos gastos com defesa e segurança nacional e educação. Da mesma forma, esses tipos de despesas não se mostraram estatisticamente significantes nas estimações. Entretanto, comunicação, saúde e saneamento, energia e recursos minerais e transporte foram as categorias de gastos públicos que mostraram relevância empírica na composição das despesas públicas. As evidências mostram que essas despesas podem ser consideradas como gastos produtivos. Para uma dada quantidade de fatores privados, melhores estradas, portos, ferrovias, comunicação, saúde e saneamento implicam uma maior produtividade desses fatores e, consequentemente, elevando o produto final.

  9. Comentarios sobre la Ley de Ordenamiento Territorial Sostenible

    Directory of Open Access Journals (Sweden)

    Arturo J. Yglesias

    2014-04-01

    Full Text Available La denominada Ley de Ordenamiento Territorial Sostenible, no fue bien recibida en el medio jurídico. Tanto los profesores de las diferentes materias de Derecho de nuestra Facultad como las asociaciones profesionales y otros grupos e juristas de nuestro medio, formularon reservas de diverso calibre sobre el texto de la ley que van desde sus aspectos adjetivos como la terminología y redacción hasta cuestiones sustanciales como lo que ella dice sobre el régimen de la propiedad territorial y otras cuestiones vinculadas.Desde el discurso político vimos lanzar opiniones iracundas y alarmistas sobre las modificaciones que la ley estaría haciendo al régimen de la propiedad privada, sobre su supuesta inconstitucionalidad.Nosotros nos vamos a referir a la ley a sus antecedentes y de las críticas que se le hacían, en la parte que toca a nuestra materia, esto es en lo relativo al régimen de la propiedad y debemos decir, a vía de adelanto, que no vemos en ella nada que afecte el derecho de propiedad consagrado por la Constitución de la República, ni los principios generales que regulan la propiedad territorial conforme al Código Civil, conforme a la vieja ley de Centros Poblados, sus modificativas ni demás normas sobre la materia.

  10. The clinical application of cosmetic repair of anterior teeth by 3M nano resin%3M纳米树脂在前牙美容修复中的临床应用观察

    Institute of Scientific and Technical Information of China (English)

    王栋

    2013-01-01

    目的:观察3M纳米树脂应用于前牙缺损美容修复的临床效果。方法:将2007年以来147例患者,256颗患牙通过酸蚀冲洗三步法粘接系统进行树脂美容修复。根据评价标准,定期随访,观察修复的效果。结果:6个月后复查,3M纳米树脂修复前牙成功率为97.54%,24个月后复查,成功率为93.01%。结论:3M 纳米树脂固位美观性好,非常适合前牙缺损的美容修复。%Objective:To evaluate the clinical prosthetic effect of by reparation of 3M nano resin in anterior teeth. Methods:147 patients since 2007 were enrol ed in the study. They were used resin for cosmetic teeth restoration by etch-and-rinse three-step adhesive system. According to the evaluation criteria, al patients were fol owed-up on a regular basis and observed the effect of the repair. Results:after 6 months and 24 months, the success rates of the reparation of 3M nano resin in anterior teeth were 97.54%and 93.01%respectively. Conclusion:3M nano resin has good retentive and aesthetic property and is fit for cosmetic repair of anterior teeth.

  11. Corrosion behaviour of groundnut shell ash and silicon carbide hybrid reinforced Al-Mg-Si alloy matrix composites in 3.5% NaCl and 0.3M H2SO4 solutions

    Directory of Open Access Journals (Sweden)

    Kenneth Kanayo ALANEME

    2015-05-01

    Full Text Available The corrosion behaviour of Al-Mg-Si alloy based composites reinforced with groundnut shell ash (GSA and silicon carbide (SiC was investigated. The aim is to assess the corrosion properties of Al-Mg-Si alloy based hybrid reinforced composites developed using different mix ratios of GSA (a cheaply processed agro waste derivative which served as partial replacement for SiC and SiC as reinforcing materials. GSA and SiC mixed in weight ratios 0:1, 1:3, 1:1, 3:1, and 1:0 were utilized to prepare 6 and 10 wt% of the reinforcing phase with Al‐Mg‐Si alloy as matrix using two‐step stir casting method. Mass loss and corrosion rate measurement was used to study the corrosion behaviour of the produced composites in 3.5% NaCl and 0.3M H2SO4 solutions. The results show that the Al-Mg-Si alloy based composites containing 6 and 10 wt% GSA and SiC in varied weight ratios were resistant to corrosion in 3.5% NaCl solution. The composites were however more susceptible to corrosion in 0.3M H2SO4 solution (in comparison with the 3.5% NaCl solution. It was noted that the Al-Mg-Si/6 wt% GSA-SiC hybrid composite grades containing GSA and SiC in weight ratio 1:3 and 3:1 respectively exhibited superior corrosion resistance in the 0.3M H2SO4 solution compared to other composites produced for this series. In the case of the Al-Mg-Si/10 wt% GSA-SiC hybrid composite grades, the corrosion resistance was relatively superior for the composites containing a greater weight ratio of GSA (75% and 100% in 0.3M H2SO4 solution.

  12. Comparison of 3M Petrifilm Aerobic Count Plates to standard plating methodology for use with AOAC antimicrobial efficacy methods 955.14, 955.15, 964.02, and 966.04 as an alternative enumeration procedure: collaborative study.

    Science.gov (United States)

    Nelson, Maria T; LaBudde, Robert A; Tomasino, Stephen F; Pines, Rebecca M

    2013-01-01

    A multilaboratory study was conducted to determine the equivalence of the 3M Petrifilm Aerobic Count Plate and standard plating methodology for measuring viable bacteria and spores recovered from hard-surface carriers (stainless steel and porcelain), also known as "control carrier counts," used in AOAC antimicrobial efficacy test methods. Six laboratories participated in the study in which carriers inoculated with Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella enterica, and spores of Bacillus subtilis were evaluated using 3M Petrifilm Aerobic Count (AC) plates and standard plating side-by-side. The data were analyzed using a matched-pair t-test to determine the between-method effect with confidence intervals. For all test organisms pooled across all laboratories, the mean difference in log10 concentration between the standard plate count method and 3M Petrifilm AC Plates was -0.012, with a 95% confidence interval of (-0.090, +0.066), which was well within the -0.5, +0.5 interval established as the acceptance criterion. The between-carrier SD averaged 0.139; the between-replicate SD was 0.050. The carrier reproducibility, given that a single replicate per carrier is done, was estimated to be 0.148. Although differences were seen in the final concentrations of the test organisms among laboratories, there were no statistical differences between the enumeration methods. Based on the results from this study, 3M Petrifilm AC Plates are equivalent to standard plating methodology and can be used as an alternative procedure for the enumeration of test organisms used in AOAC Methods 955.14, 955.15, 964.02, and 966.04.

  13. Perspectivas sobre la comunicación

    Directory of Open Access Journals (Sweden)

    Naranjo Pereira, María Luisa

    2005-12-01

    Full Text Available Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la relación humana y en las etapas donde se desarrolla. A partir de la comunicación pragmática, se analizan los axiomas comunicacionales en que se fundamenta y lo que se conoce como patologías de esos axiomas. Además se revisan las principales características que distinguen la asertividad en la comunicación y las distintas formas de manipulación que la entorpecen. Del enfoque de Virginia Satir, se presentan los diversos aspectos de la comunicación, tanto funcional como disfuncional y los modelos de comunicación propuestos por esta autora. Se revisan aspectos importantes del enfoque de la comunicación educativa, tales como el control de la distancia, la voz y el cuerpo, las palabras y el situacional; así como los elementos que bloquean el proceso de comunicación y las sugerencias acerca de formas correctas de escuchar. Además, se hace referencia a la necesidad de emplear procesos educativos más holísticos y constructivistas y una comunicación-interrelación horizontal y con equidad. Each of the diverse theories, approaches, and models of communication can provide valuable elements for the attainment of effective communication. This article presents a review of those elements with the goal of providing a better understanding and enhancement of one of the most important processes for human beings: the process of communication. This essay presents the author´s position on the topic. The importance given to human relationships and the stages

  14. Efeitos dos choques fiscais sobre o mercado de trabalho brasileiro

    Directory of Open Access Journals (Sweden)

    Diogo Baerlocher Carvalho

    2013-06-01

    Full Text Available Esse trabalho tem por objetivo entender quais os efeitos dos choques fiscais sobre o mercado de trabalho brasileiro. Em particular, utiliza se uma abordagem SVAR para avaliar esses efeitos sobre o emprego e o salário real. Os choques fiscais são identificados a partir da imposição de restrições de sinais puras sobre a relação dinâmica entre os gastos do governo, o produto real e a oferta de trabalho. As restrições são obtidas a partir de funções de resposta a impulso Bayesianas derivadas de um modelo DSGE na tradição da Nova Síntese Neoclássica. As funções de resposta a impulso obtidas a partir da abordagem SVAR mostram que choques fiscais aumentam o salário real e o emprego.

  15. Um ensaio etnofotográfico sobre o envelhecimento

    Directory of Open Access Journals (Sweden)

    Wilson José Alves Pedro

    2016-01-01

    Full Text Available O presente artigo propõe uma síntese reflexiva – imagética e textual sobre o tema processos de envelhecimento. Trata-se de um ensaio etnofográfico, a partir de registros do diário de campo, realizados em Portugal. A partir de um enquadre teórico sociológico propõe uma reflexão sobre a complexidade da apreensão dos processos de envelhecimento, enquanto fenômeno-objeto de estudo e seus determinantes. Aponta-se a necessidade de saberes interdisciplinares e procedimentos plurimetodológicos no âmbito dos estudos gerontológicos para compreender e agir sobre as multideterminações deste processo.

  16. Genetics Home Reference: 3-M syndrome

    Science.gov (United States)

    ... syndrome is a disorder that causes short stature (dwarfism), unusual facial features, and skeletal abnormalities. The name ... Additional Information & Resources MedlinePlus (1 link) Health Topic: Dwarfism Genetic and Rare Diseases Information Center (1 link) ...

  17. Apuntes sobre la noción de afectividad colectiva

    OpenAIRE

    2010-01-01

    El presente texto, que se suscribe en el paradigma de la psicología social crítica, trata la temática de la afectividad colectiva, revisando en un primer momento las nociones clásicas en psicología sobre los afectos como proceso individual para, posteriormente, esbozar la premisa sobre la afectividad como una construcción social y colectiva, noción revisada desde los planteamientos de Pablo Fernández Christlieb, quien alude a la función cultural que cumplen los afectos en el plano de la vida ...

  18. EL PENSAMIENTO SOCIAL SOBRE EL SUICIDIO EN ESTUDIANTES DE BACHILLERATO

    OpenAIRE

    Gabriel Montes Sosa; Francisco Montes Villegas

    2009-01-01

    En este estudio se analiza desde el marco de las representaciones sociales cómo los jóvenes preparatorianos manifiestan su pensamiento social sobre el suicidio. Se aplicaron cuestionarios abiertos a 169 jóvenes, mujeres y varones de bachillerato, para conocer la ocurrencia potencial de suicidio, las situaciones a las que se debe y su definición. Los resultados muestran que los jóvenes organizan su idea sobre el suicidio a partir de varios elementos en común: problemas diversos, depresión, baj...

  19. Nuevos documentos sobre Rojas Zorrilla y su teatro

    Directory of Open Access Journals (Sweden)

    Madroñal, Abraham

    2007-06-01

    Full Text Available This article contains twelve unpublished documents on Rojas Zorrilla, related to his biography and literary works (comedias and autos sacramentales. The majority are handwritten by the poet himself, and they provide new information relevant to our knowledge of his life and to the understanding of his works.Se publican una docena de documentos inéditos sobre Rojas Zorrilla referidos a su biografía y a algunas comedias y autos. En buena parte dichos documentos son autógrafos del poeta y añaden o matizan informaciones concretas sobre él y sus obras.

  20. EL IMPUESTO SOBRE BEBIDAS AZUCARADAS EN ESPAÑA

    OpenAIRE

    Vicente Ortún; López-Valcárcel, Beatriz G; Jaime Pinilla

    2016-01-01

    Este artículo aporta una revisión crítica acerca de los retos a los que se enfrentan los impuestos sobre las bebidas azucaradas como instrumento de políticas de salud, para revertir la tendencia epidémica de la obesidad. Se valoran las experiencias de los países más significados, en particular México, y se reflexiona sobre el contrapeso que ejerce la industria a las políticas antiobesidad y el poder de los lobbies. Esas políticas impositivas en pro de la salud pública han de sobreponerse a la...

  1. Santa sexualidad: concepciones de dos monjas sobre feminidad y sexualidad

    Directory of Open Access Journals (Sweden)

    Isabel Cristina Giraldo Quijano

    2009-12-01

    Full Text Available En el contexto de la religión católica, la feminidad y la sexualidad femenina se configuran según dogmas y representaciones sociales específicos, en los que la imagen de Cristo -y todo lo que ello implica- actúa como elemento fundamental en la construcción de las concepciones de las mujeres consagradas a la vida religiosa sobre sex ualidad, erotismo, cuerpo. amor. Este artículo pretende explorar desde un punto de vista sociológico las concepciones de dos monjas sobre los temas mencionados.

  2. Optimización sistólica sobre GPUs

    OpenAIRE

    Vidal, Pablo; Alba Torres, Enrique; Luna, Francisco

    2012-01-01

    En este trabajo se estudia una nueva aproximación algorítmica basada en un modelo de procesamiento paralelo conocido como computación sistólica. Este algoritmo se ejecuta sobre una Unidad de Procesamiento Gráfico empelando CUDA (Compute Unified Device Architecture). El algoritmo se compone de una matriz de celdas, donde cada una de ellas trabaja sobre una solución, realizando operaciones que la modifican para luego moverla a la celda contigua y repetir el proceso. Hemos evaluado el comportami...

  3. La socioepistemología. Un estudio sobre su racionalidad

    OpenAIRE

    Cantoral,Ricardo; López, José Iván

    2006-01-01

    Con esta investigación se pretende atender la siguiente cuestión: ¿cuál es la racionalidad que subyace a una explicación científica que se apoya en la idea de práctica?, se aborda esta pregunta haciendo una comparación con la estructura de otras teorías, que se considera tienen una cierta estabilidad. Esto nos permitió hacer inferencias sobre la racionalidad de la Socioepistemología y desde luego pretende ser también una reflexión de fondo sobre lo que significa hacer ciencia desde esta aprox...

  4. A sangre y fuego: Nuevos datos sobre la metalurgia Aguada

    OpenAIRE

    2002-01-01

    Las placas de metal figuran entre los ítemes más característicos de la cultura material de Aguada. Se conocen poco más de 30 ejemplares, los cuales se encuentran dispersos en colecciones de América y Europa y muy pocos de ellos fueron sometidos a análisis técnicos. En esta oportunidad se dan a conocer los resultados de los estudios realizados sobre tres placas Aguada, orientados a obtener información sobre las cualidades tecnológicas de los materiales, aplicable al conocimiento de la dinámica...

  5. Pregnancias : sobre cuatro lavis de Colette Deblé

    OpenAIRE

    Derrida, Jacques

    2007-01-01

    ¿Cómo citar la representación del cuerpo femenino en la Historia del Arte occidental dejándose impregnar por los patrones y modelos pictóricos masculinos pero imprimiendo, a su vez, otras huellas, las de otro cuerpo? Esta pregunta atraviesa el texto del filósofo Jacques Derrida sobre las aguadas (lavis) de la pintora francesa Colette Deblé, dando lugar a una reflexión sobre el engendramiento, el parto y la cita pictórica. En el trabajo de Colette Deblé, el legado de la Historia del Arte y su ...

  6. Monografía sobre los determinantes sociales de salud

    OpenAIRE

    Domínguez Santamaría, Mónica

    2012-01-01

    Las desigualdades en salud es uno de los problemas de salud que más preocupa a los responsables de Salud Pública. Las desigualdades sociales en salud han aumentado en los últimos años. Y es previsible que con la crisis económica actual el problema se agudice. El propósito de este trabajo es hacer una revisión bibliográfica sobre los documentos más importantes en los últimos cinco años sobre determinantes sociales de salud, que son las circunstancias en que las personas viven, condicionadas po...

  7. Efectos del consumo moderado de cerveza sobre la salud cardiovascular

    OpenAIRE

    Sendino Sedano, Pablo José

    2015-01-01

    La cerveza es una bebida fermentada elaborada a partir de cebada malteada. Entre sus componentes se encuentran el etanol (excepto en la cerveza sin alcohol) y los polifenoles, ambos con numerosos efectos sobre la salud humana, y en especial sobre la salud cardiovascular. Así mismo la práctica de ejercicio de forma regular es un hábito saludable. El sistema cardiovascular tiene numerosas funciones muy importantes en el organismo, y también mucha patología relacionada. Uno de los cuadros clínic...

  8. Santa sexualidad: concepciones de dos monjas sobre feminidad y sexualidad

    OpenAIRE

    Isabel Cristina Giraldo Quijano

    2009-01-01

    En el contexto de la religión católica, la feminidad y la sexualidad femenina se configuran según dogmas y representaciones sociales específicos, en los que la imagen de Cristo -y todo lo que ello implica- actúa como elemento fundamental en la construcción de las concepciones de las mujeres consagradas a la vida religiosa sobre sex ualidad, erotismo, cuerpo. amor. Este artículo pretende explorar desde un punto de vista sociológico las concepciones de dos monjas sobre los temas mencionados....

  9. Concepciones implícitas sobre el desarrollo infantil

    OpenAIRE

    Vilar Martínez, C.; Blasco Cubedo, María Jesús; Hernández Blasi, Carlos

    2001-01-01

    Setenes Jornades de Foment de la Investigació de la FCHS (Any 2001-2002) Partiendo del trabajo de Martí, E. et al. (1994) “ Ideas previas de una población universitaria sobre el desarrollo infantil” hemos realizado un estudio descriptivo para identificar las concepciones implícitas del conocimiento que tienen estudiantes universitarios sobre el desarrollo infantil. La muestra estaba constituida por 111 estudiantes de la Universitat Jaume I, con una media de edad de 19 años. Median...

  10. SOBRE LA DEFINICIÓN DE LA LEY MORAL

    OpenAIRE

    2013-01-01

    Presentamos al lector de lengua castellana una traducción del texto "Sulla definizione della legge morale", del filósofo trentino Antonio Rosmini. Se trata de una respuesta elaborada por el autor para dar cuenta de las observaciones que vertiera sobre su teoría moral el jesuita Luigi Dmowski. Este último, en su libro Institutiones philosophiae arremete contra el filósofo de Trento y su tesis de que la ley moral es una noción de la mente, con cuyo uso se realiza un juicio sobre la moralidad de...

  11. Colonialismo e nacionalismo nos escritos de Marx sobre a Irlanda

    OpenAIRE

    Rafael Afonso da Silva

    2013-01-01

    Esta pesquisa tem como objeto a reflexão de Marx sobre o tema do colonialismo conduzido por países capitalistas ou, mais concretamente, pelo país capitalista que dominava o maior império colonial à época, a Inglaterra. De modo ainda mais específico, a pesquisa concentra-se nos escritos de Marx sobre a Irlanda. Esses escritos são examinados contra o pano de fundo de um conjunto mais amplo de escritos de Marx em torno do impacto do colonialismo britânico, expondo as contínuas reavaliações e rev...

  12. Pregnancias : sobre cuatro lavis de Colette Deblé

    OpenAIRE

    Derrida, Jacques

    2007-01-01

    ¿Cómo citar la representación del cuerpo femenino en la Historia del Arte occidental dejándose impregnar por los patrones y modelos pictóricos masculinos pero imprimiendo, a su vez, otras huellas, las de otro cuerpo? Esta pregunta atraviesa el texto del filósofo Jacques Derrida sobre las aguadas (lavis) de la pintora francesa Colette Deblé, dando lugar a una reflexión sobre el engendramiento, el parto y la cita pictórica. En el trabajo de Colette Deblé, el legado de la Historia del Arte y su ...

  13. Concurrencia de titulares sobre la creación intelectual

    OpenAIRE

    Navarro Costa, Ruth

    1994-01-01

    El contenido de la tesis presentada bajo el titulo "Concurrencia de titulares sobre la creación intelectual" comprende un estudio pormenorizado de las obras debidas a un sujeto plurimo. Así, los capítulos i, ii y iii tratan respectivamente de las obras en colaboración, colectivas y derivadas como supuestos mas emblemáticos de cotitularidad sobre la obra del ingenio. Finalmente, en el capitulo iv se abordan algunos supuestos heterogéneos que pueden dar lugar a situaciones de concurrencia entre...

  14. Datos sobre la vida sexual en dos ciudades colombianas

    OpenAIRE

    2012-01-01

    Uno de los temas más difíciles de investigar científicamente es el referente a la vida sexual, principalmente por la dificultad de obtener datos precisos y verídicos sobre la conducta de los individuos. Este es un tema que se trata vagamente ó solo a través de la consulta médica ó el chiste. Resulta difícil preguntar a la gente sobre su conducta sexual y más difícil aun obtener una respuesta verdadera y clara. Este informe, aunque breve, ha logrado en parte eludir estos escollos. En primer lu...

  15. Some observations on the synthesis and electrolytic properties of (Ba1-xCax (M0.9Y0.1O3, M = Ce, Zr-based samples modified with calcium

    Directory of Open Access Journals (Sweden)

    Dudek Magdalena

    2016-03-01

    Full Text Available In this paper, the impact of partial substitution of calcium for barium in (Ba1-xCax (M0.9Y0.1 O3, M = Ce, Zr on physicochemical properties of the powders and sintered samples was investigated. The powders, with various contents of calcium (x = 0, 0.02, 0.05, 0.1, were prepared by means of thermal decomposition of organometallic precursors containing EDTA. All of the BaCeO3-based powders synthesised at 1100 °C were monophasic with a rhombohedral structure, however, completely cubic BaZrO3-based solid solutions were obtained at 1200 °C. A study of the sinterability of BaZr0.9Y0.1O3 and BaCe0.9Y0.1O3-based pellets was performed under non-isothermal conditions within a temperature range of 25 to 1200 °C. The partial substitution of barium for calcium in the (Ba1-xCax (M0.9Y0.1 O3, M = Ce, Zr solid solution improved the sinterability of the samples in comparison to the initial BaCe0.9Y0.1O3 or BaZr0.9Y0.1O3. The relative density of calcium-modified BaCe0.9Y0.1O3-based samples reached approximately 95 to 97 % after sintering at 1500 °C for 2 h in air. The same level of relative density was achieved after sintering calcium-modified BaZr0.9Y0.1O3 at 1600 °C for 2 h. Analysis of the electrical conductivity from both series of investigated materials showed that the highest ionic conductivity, in air and wet 5 % H2 in Ar, was attained for the compositions of x = 0.02 to 0.05 (Ba1-xCax(M0.9Y0.1O3, M = Zr, Ce. The oxygen reduction reaction on the interface Pt│BaM0.9Y0.1O3, M = Ce, Zr was investigated using Pt microelectrodes. Selected samples of (Ba1-xCax (M0.9Y0.1O3, M = Zr, Ce were tested as ceramic electrolytes in hydrogen-oxygen solid oxide fuel cells operating at temperatures of 700 to 850 °C.

  16. Controversia sobre el origen del anime. Una nueva perspectiva sobre el primer dibujo animado japonés

    OpenAIRE

    2012-01-01

    Recientes descubrimientos sobre los orígenes de la animación japonesa muestran indicios consistentes de que la primera animación nipona en formato cinematográfico data de la década de 1900, lo que puede llegar a cuestionar algunos aspectos fundamentales que sustentan la historia de la animación tradicional. En este artículo se realiza un análisis de la documentación existente sobre las primeras animaciones japonesas, demostrando que este peculiar estilo de animación tuvo en realidad un origen...

  17. Puente metálico sobre el río Save

    Directory of Open Access Journals (Sweden)

    Schafer, G.

    1963-03-01

    Full Text Available The original «Kinfi Alexander» suspension bridge over the Save river, Yugoslavia, which was destroyed during the last world war has been reconstructed, after organising an international prize award for its design. 32 projects from various countries were submitted. The chosen design is a metal structure, of 261 ms span. The arch of the main span has a hollow box section. The deck consists of an orthotropic slab, which has been subjected to a number of tests. The bridge has three spans (two approach and one central span, and was built without scaffolding, i. e., by cantilevering it from the springers. The roadway is 12 ms wide and there are two 3 ms wide footways. The box section arch girders are 9.60 ms deep over the piles, and 4.50 ms at the crown. The slopes on either side of the crown are 0.7 and 0.25%, respectively. The deck is very rigid, and is well capable of supporting the design loads and windage.El primitivo puente colgante Rey Alejandro, sobre el río Save, Yugoslavia, destruido durante la última guerra mundial, ha sido reconstruido por la vía de concurso internacional, al cual se presentaron 32 proposiciones de diferentes países. La solución aceptada fue una estructura metálica de 261 m de luz. El arco de este tramo tiene una sección hueca en forma de cajón. El tablero se compone de una placa ortotrópica, de la que, previamente, se han realizado varios ensayos. La obra, de tres tramos —dos para los accesos y uno central—, se construyó por procedimientos sin andamiaje, es decir, en voladizo. La anchura de la calzada es de 12 m, y dos andenes, de 3 m cada uno, para peatones. Los arcos de las vigas cajón tienen 9,60 m de canto sobre las pilas y 4,50 m en la clave. Las pendientes hacia uno y otro lado de la clave son del 0,7 y 0,25%, respectivamente. La rigidez del tablero es perfecta y suficiente para- soportar las cargas previstas y para transmitir los efectos del viento a las pilas.

  18. EFECTIVIDAD DE DIFERENTES TRATAMIENTOS EN LA ADHESIÓN SOBRE CERÁMICA DE ZIRCONIO

    Directory of Open Access Journals (Sweden)

    Laura Angélica Hurtado Fino

    2011-12-01

    Full Text Available Normal 0 21 false false false ES-CO X-NONE X-NONE Objetivos: Evaluar el efecto en la adhesión sobre cerámica de zirconio de diferentes tratamientos en ensayos de cizalla. Métodos: 160 cilindros de resina fueron unidos a especímenes de cerámica de zirconio, cerámica feldespática y metal siguiendo diferentes protocolos. Se utilizaron 4 tipos de cemento y se utilizaron 16 diferentes métodos de adhesión. Los cilindros se almacenaron por 24 horas en ambiente húmedo a 37ºC y luego sometidos a prueba de resistencia al corte. El análisis estadístico fue realizado con el análisis de varianza (ANOVA a una y dos vías; procedimiento de diferencia mínima significativa (LSD de Fisher bajo un nivel de significancia del 5% y prueba de Kruskal-Wallis. Resultados: el zirconio tratado, luego de la cerámica feldespática fue el que presentó mayor resistencia de unión al corte. La media general más grande de los grupos de cerámica de zirconio fue el grupo 5 (acido fluorhídrico 8.0859 Mpa, seguida del grupo 8 (coral experimental, 7.62965 Mpa, el grupo 7 (acido nítrico, 6.7618 Mpa, el grupo 6 (acido sulfúrico, 6.24245 Mpa y el grupo 4 (zirconio tratado únicamente con silano, 3.66635 Mpa. En general para la cerámica de zirconio con los diferentes tratamientos superficiales se observa un mejor comportamiento en promedio del cemento RelyX® U100 (3M (8.00428 Mpa que el Multilink® (IVOCLAR (4.95018 Mpa con una diferencia estadísticamente significativa. Conclusión: Los tratamientos superficiales como el acido nítrico a temperatura ambiente y coral experimental sobre la cerámica de zirconio, son una alternativa de fácil manipulación para mejorar valores de adhesión.

  19. Teorización sobre el uso de precedentes jurisprudenciales en Colombia

    Directory of Open Access Journals (Sweden)

    Abdón Mauricio Rojas

    2015-11-01

    Full Text Available Dando por descontado que los jueces y abogados colombianos usan cada vez con mayor disciplina y regularidad las sentencias judiciales, en el marco de sus litigios y en la resolución de casos nuevos, este artículo intenta presentar algunas sugerencias para reformular teóricamente algunos de los puntos de partida en el examen del precedente, tanto en la versión del análisis estático como en la del análisis dinámico. El objetivo de este trabajo es ayudar en la labor constante e inevitable que soportamos algunos abogados, en el sentido de teorizar sobre el tipo de cosas que hacemos en la práctica diaria. El artículo empieza con la enunciación de las 3 más importantes explicaciones disponibles en nuestro contexto –y dos variaciones intermedias–, que justifican el creciente uso de las sentencias judiciales como parte del quehacer profesional. Posteriormente, presenta las tres partes de la estructura básica del argumento analógico, en el que se ubica el análisis estático de las sentencias, introduciendo en ese punto algunas sugerencias de reformulación analítica, especialmente aquellas que den cabida a la analogía a fortiori; todo ello, de la mano de algunas contribuciones, bastantes conocidas por cierto, que la filosofía del lenguaje ha realizado en relación con los distintos actos de habla y las metodologías para su interpretación. Termino con dos ejemplos que intentan mostrar cómo esta metodología –guiada fundamentalmente por las distinciones entre la fuerza ilocutiva y los efectos perlocutivos de los actos de habla, así como por la diferencia entre un problema de significado y un problema de seguimiento-, podrían funcionar en casos concretos. Cierro con algunos interrogantes sobre la manera en que se construyen los análisis relacionales de sentencias.

  20. Una mirada sobre lo popular. Reflexiones sobre el etnocentrismo en el nuevo cine argentino

    Directory of Open Access Journals (Sweden)

    Gonzalo Assusa

    2013-01-01

    Full Text Available La emergencia del nuevo cine argentino desata una serie de debates teóricos. Probablemente una de las caracterizaciones más convincentes es la que lo define como surgido de una misma crisis, no sólo en el campo cinematográfico, sino también de una misma crisis social. En el marco de un análisis sociológico de este fenómeno cultural, el presente trabajo planteará una hipótesis de lectura para algunas de las producciones audiovisuales del denominado nuevo cine argentino, en pos de establecer conceptualmente la estructuración desde el polo productivo de la elaboración imaginaria de esta crisis social, concretamente, de la emergencia de las clases populares en sus filmes. Para finalizar, se evaluará la productividad de la hipótesis de lectura basada en una definición teórica de lo popular, aplicándola a un cuerpo de filmes del realizador argentino Adrián Caetano, para concluir con reflexiones sobre la importancia del cruce entre la estructuración textual y la estructuración en el momento del consumo.

  1. Reflexiones sobre la corrupción y su impacto sobre la salud

    Directory of Open Access Journals (Sweden)

    Alfredo Jácome Roca

    2017-04-01

    Existe una gran variedad de teorías biológicas, psicológicas, sociológicas y económicas que explican la conducta corrupta, algunas de las cuales profundizan sobre cómo las prácticas generalizadas de violación de las reglas pueden afectar la honestidad individual y la voluntad intrínseca de seguir las leyes. Así, por ejemplo, hay quienes sostienen que el engaño es común en el mundo animal y hace parte del proceso evolutivo; en ese sentido, se considera como un acto natural, innato y que responde a la lucha por la supervivencia. Por eso, se encuentran especies que se camuflan, se mimetizan, se hacen las muertas, utilizan químicos que no permiten ver la gravedad de un ataque, consiguen que el competidor las considere más grandes de lo que realmente son adoptando ciertas posturas, etc.

  2. Construcciones sociales sobre mujeres desde el discurso jurídico en sentencias penales sobre infanticidio

    Directory of Open Access Journals (Sweden)

    María Eugenia Gastiazoro

    2015-12-01

    Full Text Available El infanticidio como figura penal se suprime del Código Penal Argentino en 1994, para ser una figura de homicidio agravado por el vínculo con prisión o reclusión perpetua. Diez años después de su última derogación, el caso Romina Tejerina en Jujuy generó una serie de cuestionamientos respecto de su penalización. Otro caso, que tomó estado público fue el de Eli Díaz en la ciudad de Villa Dolores en Córdoba, juzgada en el 2006, siendo (en contraposición al caso Tejerina absuelta por una mayoría compuesta solo de ciudadanos comunes (jurados. En el presente trabajo se analiza la construcción y la producción que desde el discurso jurídico se hace de las diferentes mujeres en los casos de infanticidio. A su vez, estas imágenes se comparan con las representaciones que los legisladores tuvieron en el debate del Congreso del año 2010 cuando se intentó reponer la figura. La sujeción del género centrada en la buena o mala madre, mujer, esposa, en intersección con otras dimensiones de clase social, y edad, se categoriza en el discurso de los tribunales de acuerdo a imaginarios sociales que sostienen una identidad normativa sobre estas mujeres.

  3. SOBRE LA PAZ Y LOS DIÁLOGOS. CONSIDERACIONES SOBRE EL PAPEL DE LA SOCIEDAD CIVIL

    Directory of Open Access Journals (Sweden)

    William Ortiz Jiménez

    2014-10-01

    Full Text Available El ensayo hace una reflexión en torno al proceso de paz que se llevó a cabo en el gobierno del presidente Andrés Pastrana, y la participación que tuvo la sociedad civil en este asunto. Pero, trasciende, además, a la situación actual del conflicto en Colombia. A partir de las formulaciones de varios teóricos, entre los que se destacan Daniel Pécaut, Cohen, y Arato., Margarita Bonamusa, María Teresa Uribe, Daniel García-Peña, Habermas, Rawls, entre otros, se fortalece un marco teórico y de referencia bastante sólido para mostrar cómo lo público es indispensable en las acotaciones que lleven a la solución de los conflictos. Sin el concurso de lo público, tampoco sería viable la participación de la sociedad civil. Los espacios de solución de conflictos, el ágora, en palabras de Hanna Arendt, es el lugar esencial para la discusión, el consenso y los acuerdos. En política, la esfera de lo público prima sobre lo privado, porque el reconocimiento de las libertades, manifestaciones y la plenitud de los derechos sólo se logra en lugares comunes.

  4. Apontamentos sobre Economia Política em Rousseau

    Directory of Open Access Journals (Sweden)

    Antônio Marcos Alves Sá

    2011-12-01

    Full Text Available O presente artigo tem o objetivo de apontar alguns elementos acerca da relação entre economia, a política no pensamento filosófico de Jean-Jacques Rousseau, a partir do seu Tratado sobre Economia Política.

  5. Indagación sobre la visión

    OpenAIRE

    Solbes Matarredona, Jordi

    2011-01-01

    Indagación sobre la luz y la visión usando objetos de la vida cotidiana: camara oscura y su fabricación con tubos de cartón, espejos planos, concavos y convexos (cucharas pulidas), lentes convergentes y divergentes, funcionamiento del ojo, etc.

  6. Sobre o estilo e o modo de falar e escrever

    Directory of Open Access Journals (Sweden)

    Pedro Caruso

    2001-02-01

    Full Text Available

    Este trabalho apresenta o texto crítico de uma Lei ou Provisão de Filipe I , rei de Portugal, sobre as diversas formas de tratamento no período arcaico da língua portuguesa.

  7. Aspectos sobre el matrimonio en el Derecho Romano arcaico

    OpenAIRE

    Fern??ndez Baquero, Mar??a-Eva

    2004-01-01

    El libro "El Derecho de Familia: De Roma al Derecho actual" donde se encuentra recogido este cap??tulo "Aspectos sobre el matrimonio en el Derecho Romano arcaico" (p??gs. 193-207) tiene un total de 853 p??ginas.

  8. Indagación sobre la visión

    OpenAIRE

    Solbes Matarredona, Jordi

    2011-01-01

    Indagación sobre la luz y la visión usando objetos de la vida cotidiana: camara oscura y su fabricación con tubos de cartón, espejos planos, concavos y convexos (cucharas pulidas), lentes convergentes y divergentes, funcionamiento del ojo, etc.

  9. II Foro-Taller Sobre Vacunación

    National Research Council Canada - National Science Library

    Yolanda Ruán de la Carrera; Elmer Escobar Cifuentes

    2012-01-01

    ... su conferencia sobre “Presente y futuro de la vigilancia epidemiológica de las enfermedades inmuno-prevenibles en Colombia”. A continuación siguió la ponencia “Introducción de nuevas vacunas: procesos...

  10. La investigación sobre el estudiante universitario colombiano

    Directory of Open Access Journals (Sweden)

    Americo Calero

    1989-04-01

    Full Text Available RESUMEN El artículo presenta de forma general  una revisión de los trabajos realizados  a nivel nacional sobre el estudiante universitario colombiano, identificando las distintas tendencias que se han dado en este tipo de investigaciones: Macro institucional, política, socioeconómica, vida universitaria.

  11. Consideraciones del bioderecho sobre la eutanasia en Colombia

    Directory of Open Access Journals (Sweden)

    José Antonio García Pereáñez

    2017-01-01

    Full Text Available Este artículo aborda de manera reflexiva las incidencias del bioderecho sobre situaciones de eutanasia en Colombia, al interpretar conflictos morales y jurídicos suscitados por las sentencias de la Corte Constitucional C239 de 1997, T970 de 2014 y la Resolución del Ministerio de Salud y Protección Social 1216, de 2015. El propósito fundamental es el análisis de las decisiones judiciales sobre el final de la vida humana. Por lo tanto, se realiza una revisión de la construcción histórica y jurídica del concepto de eutanasia y se propone la discusión sobre su manejo jurídico y su influencia en el colectivo moral. Asimismo, se diserta sobre el concepto de dignidad humana y muerte digna, como precedentes para dirimir los conflictos éticos que la eutanasia suscita. Al final, se analiza el caso de don Ovidio González, quien se convirtió en 2015 en el primer colombiano en recibir la eutanasia de manera legal dentro del sistema de salud.

  12. Sobre-educación en el mercado laboral colombiano

    Directory of Open Access Journals (Sweden)

    Jhon James Mora

    2008-12-01

    Full Text Available Este artículo analiza la sobre-educación en Colombia con datos de individuos y empresas compilados por el Servicio Nacional de Aprendizaje de Colombia en 2006, encuentra que la probabilidad de estar sobre-educado es del 14% y que depende de la movilidad entre áreas de desempeño, la experiencia, el género, el tamaño de la empresa y el nivel de educación. Los trabajadores sobre-educados ganan un 2% menos que los trabajadores correctamente educados, conforme al patrón internacional. Los resultados también muestran que la probabilidad de que los profesionales permanezcan en la misma área de desempeño aumenta con la experiencia, que cuanto mayor es la sobre-educación menor es la probabilidad de permanecer en dicha área y que los trabajadores con postgrado tienen menor probabilidad de permanecer en su área de desempeño.

  13. Pensamiento escolástico actual sobre el evolucionismo

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    Jorge Enrique Leal G.

    1962-07-01

    A este propósito nos ha parecido no solo conveniente, sino quizá útil, ensayar un recuento así sea somero y sintético, sobre las ideas que en la actualidad abriga la escuela escolástica en sus principales matices.

  14. Sobre el potencial teorico de las representaciones sociales en el campo de la comunicacion

    National Research Council Canada - National Science Library

    Rodriguez Salazar, Tania

    2009-01-01

    En este articulo se desarrollan algunas reflexiones teoricas y metodologicas sobre como la teoria de las representaciones sociales podria ser utilizada en el campo de los estudios sobre comunicacion...

  15. Tiempo de feminismo. Sobre feminismo, proyecto ilustrado y postmodernidad, de Celia Amorós [Ressenya

    OpenAIRE

    Campillo, Neus

    1998-01-01

    Se trata de una reseña sobre el libro Amorós, C., Tiemp de feminismo. Sobre feminismo, proyecto ilustrado y postmodernidad. Madrid, Cátedra, Universitat de Valencia, Instituto de la Mujer, 1997, 463 pp.

  16. A cis-acting element known to block 3' mRNA degradation enhances expression of polyA-minus mRNA in wild-type yeast cells and phenocopies a ski mutant.

    Science.gov (United States)

    Brown, J T; Johnson, A W

    2001-11-01

    mRNA lacking a 3' polyA tail is not translated efficiently in wild-type eukaryotic cells, but is translated efficiently in yeast ski mutants. This enhanced expression could be due to altered translational specificity. However, as the SKI genes are required for 3' mRNA degradation, it could be a consequence of inhibition of 3' mRNA decay. Therefore, we asked if inhibition of 3' decay of a polyA-minus mRNA in cis would allow its efficient expression in wild-type cells. Capped in vitro reporter transcripts were prepared with or without a 3' cis-acting element known to inhibit 3' degradation (oligoG) and electroporated into yeast cells. The addition of oligoG to a polyA-minus mRNA enhanced expression 30-fold in wild-type cells. This level of expression was the same as that for an oligoG-minus, polyA-minus transcript in a ski mutant. The addition of oligoG did not significantly enhance the expression of polyA-minus mRNA in a ski mutant. The oligoG-dependent increase in expression was due to an increase in initial rate of translation and an increase in the functional half-life of the mRNA, similar to the effects observed in a ski mutant. The enhanced expression of the oligoG-containing RNA did not require Pab1p. We conclude that the enhanced translation of polyA-minus RNA in a ski mutant is due to inhibition of 3' mRNA degradation. Furthermore, a polyA-minus mRNA is expressed in wild-type cells when terminated in an element known to inhibit 3' decay in cis.

  17. Functionalization of N2 to NH3 via direct N ≡ N bond cleavage using M(III)(NMe2)3 (M=W/Mo): A theoretical study

    Indian Academy of Sciences (India)

    Sambath Baskaran; Perumal Balu; Chinnappan Sivasankar

    2015-01-01

    Atmospheric N2 can be cleaved directly to yield metal-nitride (before proceeding to the functionalization of N of coordinated N2) and subsequently functionalized to ammonia using M(III)(NMe2)3 (M = W/Mo) as a catalyst, and suitable proton and electron sources. The calculated energies of thermodynamic and kinetic states of the various intermediates and transition states in the reaction coordinate to yield ammonia confirmed the viability of the proposed reaction pathway. Rationale of different pathways have been examined and discussed in detail. Changes in the structural features of the catalyst and some important intermediates and transition states have also been examined.

  18. 一些新的型为3m的3-互补(3,2;1)-frame%Some new 3-complementary (3,2;1)-frames of type 3m

    Institute of Scientific and Technical Information of China (English)

    严洁

    2008-01-01

    Lamken has made investigation into 3-complementary frames of type 3m with block size 3,leaving 22 undecided values.Ten of them are determined by using starter-adder method.%Lamken 对区组大小为3,型为3m的3-互补 frame 进行了研究,剩下22个值尚未解决.我们利用 starter-adder 方法确定了其中的10个值.

  19. "Meu prazer agora é risco": sentidos sobre sexualidade entre jovens de um grupo sobre saúde

    Directory of Open Access Journals (Sweden)

    João Paulo Pereira Barros

    2013-04-01

    Full Text Available A sexualidade assumiu a condição de centralidade subjetiva pelo entrecruzamento de diversos demarcadores da Modernidade, como a legitimação do saber-verdade da ciência, a afirmação da individualidade e a institucionalização dos segmentos infanto-juvenis. Partindo dessa premissa, este artigo analisa sentidos produzidos por jovens sobre "sexualidade" em um grupo de discussão sobre saúde, com base em uma pesquisa-intervenção operacionalizada por observações-participantes e pela formação de oficinas sobre saúde, em uma escola pública de Fortaleza. Acerca dos sentidos sobre "sexualidade", as articulações entre "sexualidade" e "risco" se sobressaíram em relação às conexões entre "sexualidade" e "prazer". Isso sugere a força de um viés educativo baseado na scientia sexualis, aludido por Michael Foucault, operando com uma visão normativa-prescritiva da sexualidade, reiterando-a, mediante o signo da "prevenção", como tecnologia de governo. Usando como ferramenta o conceito de biopolítica, aponta-se que tais questões remetem à instalação de um paradigma de "gestão do risco" na contemporaneidade.

  20. Narrativas sobre síndrome de Down no Festival Internacional de Filmes sobre Deficiência Assim Vivemos

    Directory of Open Access Journals (Sweden)

    Ana Cristina Bohrer Gilbert

    Full Text Available O Festival Internacional de Filmes sobre Deficiência Assim Vivemos acontece bienalmente no Brasil desde 2003. Busca engajar a audiência em novas perspectivas sobre deficiência por meio de filmes, atividades interativas, imagens e discursos institucionais. Neste artigo, analisam-se os filmes cujo tema central é a síndrome de Down, exibidos entre 2003 e 2013, com o objetivo de examinar o tipo de construção narrativa e as imagens e os significados sobre pessoas com essa condição que são veiculados no festival. Foram utilizadas estratégias etnográficas no tratamento do material empírico e procedimentos semióticos de leitura isotópica na sua análise. Foram identificados três núcleos narrativos principais que acompanham o desenvolvimento teórico sobre deficiência, sendo que um deles apresenta-se alinhado com o que tem sido denominado de ‘estética da deficiência’.

  1. 自酸蚀黏结剂加树脂直接充填深龋的临床观察%Clinical effect of Xeno III as 3 m Filtek P60 on treatment of deep caries

    Institute of Scientific and Technical Information of China (English)

    佟小辉; 季丽玢

    2013-01-01

    目的 评价用自酸蚀黏结剂XenoIII(XO)和树脂直接充填深龋窝洞和用全酸蚀黏结剂:Single bond 2加玻璃离子垫底树脂充填深龋窝洞的敏感性比较.方法 选取166个患深龋的磨牙,随机分为实验组和对照组,实验组使用自酸蚀黏结剂XenoIII处理窝洞后直接用树脂3 m Filtek P60充填,对照组采用玻璃离子水门汀(GIC)垫底,后用全酸蚀黏接剂Sing bond 2处理窝洞,树脂3 m Filtek P60充填.分别与充填后7 d,6个月和1年观察.结果实验组和对照组在术后7 d,6个月和1年的敏感性无显著性差异.结论 自酸蚀黏结剂能有效降低树脂充填深龋后的敏感性,提高牙髓的存活率,且操作简单.

  2. Comparative study of the plasma globulin level, CD21(-) B-cell counts and FOXP3 mRNA expression level in CD4(+) T-cells for different clinical stages of feline immunodeficiency virus infected cats.

    Science.gov (United States)

    Takano, Tomomi; Hosoya, Shinobu; Shibao, Akari; Nagasaki, Bunpei; Yoshioka, Hisao; Satoh, Ryoichi; Hohdatsu, Tsutomu

    2012-02-01

    Feline immunodeficiency virus (FIV) infection leads to hypergammaglobulinemia through mechanisms that remain poorly understood. We investigated changes in plasma globulin level, B cells, and T cells with progression of the clinical stage of FIV-infected cats. We classified FIV-infected cats into the stage of Asymptomatic carrier (AC) and AIDS-related complex (ARC) based on the clinical symptoms, and measured the plasma globulin level, the CD4(+) T-cell counts, and analyzed surface markers of B cells. We investigated the relationship between the plasma globulin level and regulatory T cells (Tregs) using the Forkhead box P3 (FOXP3) mRNA expression level. In FIV-infected cats, the plasma globulin level and the surface immunoglobulin (sIg)(+) CD21(-) B-cell counts were increased, whereas the CD4(+) T-cell counts were decreased compared with specific-pathogen free (SPF) cats. The mRNA expression of Blimp-1 (master gene of plasma cells) was increased in peripheral blood, and the FOXP3 mRNA expression level was decreased in CD4(+) T-cells. These immunological changes were marked in the ARC stage. These data indicate that the decrease of Tregs and the increase of plasma cells lead to hypergammaglobulinemia.

  3. Cultivares e portaenxertos sobre o vigor de plantas de pereira europeias

    Directory of Open Access Journals (Sweden)

    Bruno Dalazen Machado

    2013-09-01

    Full Text Available A cultura da pereira (Pyrus communis possui grande potencial de expansão no sul do Brasil devido às condições climáticas e solo. A carência de informações a respeito da(s melhor(es combinação(ões de cultivares copa de pereira europeia e portaenxertos, quanto ao aspecto vegetativo e potencial produtivo, tem limitado o cultivo. O objetivo do trabalho foi avaliar a influência de cultivares copa de pereira europeia e portaenxertos de marmeleiro (Cydonia oblonga sobre o vigor e variáveis de plantas. Os experimentos foram conduzidos em pomares comerciais da cidade de Fraiburgo, Estado de Santa Catarina, durante os ciclos de cultivo 2008/09, 09/10 e 10/11. As cultivares avaliadas foram 'Packham's Triumph', 'Santa Maria', 'Rocha' e 'Abbè Fetel' e os portaenxertos de marmeleiro EMC e Adams. O espaçamento de plantio foi de 0,3m entre plantas e 4m entre linhas. As variáveis analisadas foram: a. incremento de altura de plantas (m; b. incremento de volume de copa (m³; c. incremento de diâmetro do tronco da cv. 'copa' (mm; d. incremento de diâmetro do tronco do portaenxerto (mm; e. diferença de diâmetro do tronco entre a cultivar copa e o portaenxerto (mm; f. índice de fertilidade (no de gemas cm-1; g. massa fresca média total acumulada do material vegetativo das três podas de inverno (kg; h. diferença cumulativa entre a massa fresca e a massa seca dos ramos podados (kg. As diferentes combinações de cultivares e portaenxertos interferiram nas diferentes variáveis analisadas. As combinações Abbè Fetel e Rocha sobre marmelo Adams, foram significativamente mais vigorosas em termos de incremento de diâmetro do tronco da cultivar copa, incremento de altura de plantas, incremento de volume de copa e massa fresca média total acumulada do material vegetativo das podas de inverno dos três anos. A combinação Santa Maria sobre marmelo Adams apresentou vigor intermediário significativo de plantas de acordo com o incremento em volume

  4. Centros de informação sobre medicamentos no Brasil : passado, presente e perspectivas do Sistema Brasileiro de Informação sobre Medicamentos

    OpenAIRE

    Carlos Cezar Flores Vidotti

    1999-01-01

    Resumo: Introdução. Após discussão dos diferentes fatores que justificam aexistência de Centros de Informação sobre Medicamentos (CIM), foram apresentadas as definições de informação sobre medicamentos (IM)e de centro de informação sobre medicamentos (CIM), e relacionadas às atividades usuais dos centros, tendo a informação passiva como atividade fundamental. O farmacêutico especialista em informação sobre medicamentos é o profissional com perfil mais adequado para atuar nos CIM, devendo ser ...

  5. Sobre a Pesquisa nas Artes: um discurso amoroso

    Directory of Open Access Journals (Sweden)

    Victoria Pérez Royo

    2015-09-01

    Full Text Available Este artigo resulta de um exercício de reescrita experimental e de um pensamento analógico cujo objetivo era abrir uma nova perspectiva sobre pesquisa nas artes. Metodologicamente, as diferentes figuras de amor no livro Fragmentos de um Discurso Amoroso, de Barthes, são levadas a conversar sobre a relação entre pesquisador e objeto de estudo. Essa analogia nos permite encontrar parâmetros de qualidade baseados em uma escala de valores diferentes dos hegemônicos na academia (produtividade, competitividade, inovação. Esses novos parâmetros podem constituir uma sólida base ontológica para a construção de uma nova política de pesquisa artística na academia que permita uma reconsideração radical dos processos de investigação em artes.

  6. Pregnancias. Sobre cuatro lavis de Colette Deblé

    Directory of Open Access Journals (Sweden)

    Jacques Derrida

    2013-07-01

    Full Text Available ¿Cómo citar la representación del cuerpo femenino en la Historia del Arte occidental dejándose impregnar por los patrones y modelos pictóricos masculinos pero imprimiendo, a su vez, otras huellas, las de otro cuerpo? Esta pregunta atraviesa el texto del filósofo Jacques Derrida sobre las aguadas (lavis de la pintora francesa Colette Deblé, dando lugar a una reflexión sobre el engendramiento, el parto y la cita pictórica. En el trabajo de Colette Deblé, el legado de la Historia del Arte y su mitología engendrarán una serie infinita de aguadas donde el agua no pretende “lavar” la tradición (deshacerse de ella, acabar con ella sino inundarla, mojarla, empaparla con nuevas aguas para, escurriéndola, hacerla resonar nuevamente.

  7. Concepções sobre criminalidade e modelos de policiamento

    Directory of Open Access Journals (Sweden)

    Marco Antônio de Azevedo

    Full Text Available Podem-se conceber duas perspectivas teóricas básicas para explicar a criminalidade: a culturalista e a racionalista. Da primeira derivam políticas públicas destinadas a reduzir a criminalidade através de uma atuação sobre a desorganização social. Na segunda privilegia-se uma estratégia segundo a qual o principal papel do Estado é dissuadir o criminoso da prática delituosa. Este trabalho revisa a literatura, evidenciando mitos sobre o crime e a atividade policial. São discutidos dois modelos de policiamento: um mais tradicional e reativo e outro mais preventivo, procurando-se mostrar que o racionalismo dá maior suporte teórico a políticas de segurança pública que valorizam a promoção da cidadania.

  8. Consenso Cultural sobre el Intento de Suicidio en Adolescentes

    Directory of Open Access Journals (Sweden)

    Javier Eduardo García de Alba García

    2011-01-01

    Full Text Available Este estudio buscó identificar la estructura semántica del dominio cultural, el promedio de conocimiento y el grado de consenso cultural manifestado por los adolescentes sobre el intento de suicidio. Fue un estudio cualitativo de listas libres, con un muestreo propositivo no aleatorizado de 27 adolescentes entre 13 y 18 años. Los resultados evidenciaron un solo modelo semántico. En lo estructural se identificó el problema familiar como una causa importante del intento suicida; las categorías depresión y tristeza se consideraron como signos y síntomas previos a esta tentativa y no como causas. Como estrategias de prevención, se consideró recibir información mediante pláticas o establecer conversaciones sobre los problemas. Este modelo permite proponer estrategias de prevención que privilegien el núcleo familiar.

  9. Instalación fotovoltaica sobre cubierta de nave industrial

    OpenAIRE

    Ramírez Basalo, Miguel Ángel

    2013-01-01

    El objetivo de este proyecto es el diseño y estudio de la instalación fotovoltaica con conexión a red sobre cubierta en una nave industrial, así como la iluminación interior y exterior de la misma nave. La instalación fotovoltaica sobre cubierta con conexión a red es una de las más demandadas hoy en día, y que puede reportar muchos beneficios y ventajas en el futuro. No es una necesidad real, pero se justificara su elección a través de un estudio técnico y económico, en el q...

  10. Planteamientos sobre la pobreza: una aproximación conceptual

    Directory of Open Access Journals (Sweden)

    Bertha Lucía Martínez Bernal

    2015-07-01

    Full Text Available En el presente artículo se presentan varias definiciones o conceptos para la comprensión, medición y el análisis de la pobreza. Para ello se retoma la producción escrita de diferentes estudiosos e investigadores que han hecho aportes valiosos sobre el tema. Al lado de estos conceptos se analizan los diferentes enfoques que se utilizan para aproximarse al estudio de la pobreza, aunque estas no son teorías ni explicaciones de sus causas, sino perspectivas sobre pobreza que denotan dichos enfoques. Así mismo se desarrolla una revisión de las metodologías más utilizadas en los procesos de identificación y agregación. Finalmente se interpretan las políticas públicas en los sectores sociales.

  11. EL PENSAMIENTO SOCIAL SOBRE EL SUICIDIO EN ESTUDIANTES DE BACHILLERATO

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    Gabriel Montes Sosa

    2009-01-01

    Full Text Available En este estudio se analiza desde el marco de las representaciones sociales cómo los jóvenes preparatorianos manifiestan su pensamiento social sobre el suicidio. Se aplicaron cuestionarios abiertos a 169 jóvenes, mujeres y varones de bachillerato, para conocer la ocurrencia potencial de suicidio, las situaciones a las que se debe y su definición. Los resultados muestran que los jóvenes organizan su idea sobre el suicidio a partir de varios elementos en común: problemas diversos, depresión, baja autoestima y comunicación deficiente. Así, el suicidio se objetiviza en estos esquemas y se ancla en sus relaciones existentes. Para contextualizar el estudio, en la primera parte del trabajo los autores incluyen una somera descripción de los datos estadísticos más importantes respecto del suicidio en el estado de Puebla.

  12. MITOS Y LEYENDAS SOBRE LOS JUEGOS DE ROL

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    Rocío Tizón

    2010-11-01

    Full Text Available Los juegos de rol aparecen en la década de los años 70 en Estados Unidos, creados por Gary Gigax y Dave Arneson, padres del ya famoso Dragones & Mazmorras. No obstante, fueron pocos los años de tranquilidad, ya que en su país natal se le consideró culpable de promover el suicidio de varios adolescentes que habían sido jugadores de Dragones & Mazmorras. Los engaños de la información y los prejuicios de las noticias sobre estos juegos de rol provocaron que varias personas se interesaran por este fenómeno, analizando dichos mitos y comprobando la verdad de estos rumores. Uno de estos estudiosos fue William Watson, creador de la página web The Inquirer, en la que se dedica a desmontar estos y otros tópicos sobre juegos de rol.

  13. Bombeiros: um olhar sobre a qualidade de vida no trabalho

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    Janine Kieling Monteiro

    Full Text Available Este trabalho apresenta uma intervenção no corpo de bombeiros (São Leopoldo - RS realizada pelo NEPT (Núcleo de Excelência em Psicologia do Trabalho. Utilizamos um diagnóstico com sessenta e três entrevistas semi-estruturadas sobre o trabalho e funcionamento da corporação. Partindo da análise deste, propusemos palestras sobre estresse e qualidade de vida no trabalho (QVT. Foram levantados questionamentos acerca do mito do herói e do amor pela profissão bombeiro, que deixa em segundo plano seus problemas. Destacou-se o estresse no trabalho por situações traumáticas, como risco de vida eminente e mortes nos salvamentos. Entendemos que as intervenções contribuíram como espaço de escuta que propiciou reflexões a respeito da QVT.

  14. Hölderlin: sobre la religión

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    Andrés Alfredo Castrillón Castrillón

    2014-06-01

    Full Text Available El artículo se propone dilucidar la noción de religión que tiene Friedrich Hölderlin en el ensayo “Sobre la religión”, el cual traza un pensamiento tan o más complejo de la relación hombre - dios, y hombre - comunidad, que los de filósofos como Kant o Hegel en sus reflexiones sobre Dios y la religión. Destacar por medio del análisis del ensayo cómo comprende Hölderlin la religión y cómo la vincula con la vida de los hombres en su contexto es la tarea fundamental del escrito, para concluir con las propuestas poéticas de la fundación de religiones o sus manifestaciones a través del mito.

  15. MEMORIA EMOCIONAL: EFECTOS DE LA CORTICOSTERONA SOBRE LOS RECUERDOS

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    ELIANA RUETTI

    2008-01-01

    Full Text Available Las hormonas adrenales, administradas inmediatamente antes o después de una tarea de aprendizaje, modulan la memoria. Este efecto varía de acuerdo al tiempo y a la intensidad con que se incrementan las hormonas. La liberación o administración de glucocorticoides inmediatamente antes o después de una tarea, facilitan la memoria. Por el contrario, la elevación o administración de glucocorticoides antes de una prueba de aprendizaje, deteriora la evocación de la información previamente adquirida. En este trabajo se revisan los principales estudios realizados con animales y humanos acerca del papel de los glucocorticoides sobre la memoria de eventos aversivos. A su vez se describe el efecto de la elevación aguda y crónica de las hormonas adrenales sobre la memoria.

  16. ensayo crítico sobre Oliverio Girondo

    Directory of Open Access Journals (Sweden)

    Luis Felipe González G.

    2005-01-01

    Full Text Available A partir de la aparición, por cerca de diez años, del movimiento surrealista, se hará un esbozo de algunas las características de uno de los representantes de esta escuela literaria, Oliverio Girondo, partiendo de un poema del libro Veinte poemas para ser leídos en el tranvía, del cual se encontraron dos posiciones, en apariencia antagónicas, sobre la vanguardia, derivadas en un antiestilo o decadencia de los principios modernos (Calinescu, 1991 y una posibilidad de crítica a la institución arte (Bürger, 1987. Estas posiciones permitieron establecer algunas reflexiones acerca del concepto de saturación social que postula el construccionismo social y las características generales que propone Mukarovsky (1992 sobre la teoría crítica estructuralista.

  17. Preparation and thermoelectric properties of M0.05Ca0.95MnO3%M0.05Ca0.95MnO3的制备及其热电性能

    Institute of Scientific and Technical Information of China (English)

    许洁; 魏长平; 贾坤

    2011-01-01

    采用溶胶-凝胶法,以硝酸盐为原料,在常压空气气氛中于1 000℃烧结8 h制备出CaMnO3和M0.05Ca0.95MnO3(M=Sr2+,Sm3+)块体材料。利用X线衍射、扫描电子显微镜等研究材料的物相和微观形貌,考察Sr2+和Sm3+M+掺杂对CaMnO3的高温热电性能参数Seebeck系数、电阻率和功率因子的影响。研究结果表明:制备的样品具有单一的物相,结构致密;金属离子Sr2+和Sm3+掺杂可以有效地改善其热电性能;当Sm3+的掺杂量为0.05时可获得最佳的热电性能,600℃时功率因子为23×10-5W·m-1·K-2。%CaMnO3 and M0.05Ca0.95MnO3 (M=Sr2+, Sm3+) samples were synthesized by sol-gel method and sintered in air at 1 000 "C for 8 h with nitrates as starting materials. The phase composition and microstructure were studied by XRD and SEM. Thermoelectric properties such as the Seebeck coefficient, electrical resistivity and power factor of M0.05Ca0.95MnO3 samples were studied. The results show that theM0.05Ca0.95MnO3 samples have single phase and condensed microstructure. The samples substituted by metal ions(Sr2+, Sm3+) enhance the electrical transmission performance effectively, and the highest power factor is 23×10-5 W·m-1·K-2 at 600 ℃ for the sample of Sm0.05Ca0.95MnO3.

  18. Algumas considerações informais sobre inferência

    OpenAIRE

    Ibaños, Ana

    2010-01-01

    El presente texto es una discusión informal sobre la inferencia, uno de los aspectos esenciales de la Teoría de la Relevancia (TR) de Sperber y Wilson. Desde la Lógica tradicional hasta modelos cognoscitivos, los autores trabajan con la hipótesis de que los patrones convenidos por una sociedad X que usa una lengua Y rigen las restricciones de los procesos de inferencias en un cambio comunicativo.

  19. Efectos del tipo funcional de entrenamiento sobre el ajuste lector

    OpenAIRE

    Rosalinda Arroyo Hernández; Guadalupe Mares Cárdenas

    2009-01-01

    El presente trabajo tuvo por objetivo evaluar los efectos de entrenar cinco tipos de contacto con las relaciones entre objetos y sus elaboraciones lingüísticas sobre el ajuste lector de estudiantes universitarios. Primeramente los participantes fueron expuestos a una evaluación de ajuste lector, consistente en preguntas de diferente complejidad funcional, para posteriormente ser asignados aleatoriamente a uno de cinco grupos experimentales diferenciados por el nivel de complejidad funcional d...

  20. Corpus de inscripciones sobre la esclavitud infantil en Hispania romana

    OpenAIRE

    Crespo Ortiz de Zárate, Santos

    2009-01-01

    Se presenta en este trabajo el corpus epigráfico relativo a la servidumbre infantil en Hispania romana, como base a una serie de estudios sobre la dependencia personal en este ámbito social. This work shows the epigraphic sources dealing with the children-slaves in Roman Spain and sets up a base for future studies about personal dependence in this social sphere.