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Sample records for 3m cavilon sobre

  1. Evaluación in vivo mediante microscopia confocal del efecto protector de la película barrera no irritante 3M Cavilon sobre la piel perilesional In vivo evaluation using confocal microscopy of protective effect of no-sting barrier film 3M Cavilon on periwound skin

    Directory of Open Access Journals (Sweden)

    Teresa Segovia Gómez

    2008-03-01

    Full Text Available Tradicionalmente, el manejo de las úlceras cutáneas incluye medidas que facilitan la cicatrización, tales como el buen desbridamiento, ya sea médico o quirúrgico, apósitos oclusivos, tratamiento de infección y buena nutrición; sin embargo, es importante la valoración y el tratamiento de la piel perilesional. En este sentido, recientemente, diversos autores han descrito la coexistencia de trastornos nutricionales y tróficos en la misma, muchos de ellos de causa iatrogénica, y donde el uso de la película barrera no irritante 3M Cavilon puede ser un pilar importante para una buena respuesta al tratamiento. Los objetivos que se persiguen con el presente estudio pretenden identificar las características confocales de la piel perilesional de las úlceras venosas y evaluar los cambios dinámicos que experimenta la misma tras el uso adyuvante de la película barrera no irritante 3M Cavilon en su tratamiento. Para ello, pacientes afectos con úlceras venosas de larga evolución fueron tratados durante una semana de manera convencional utilizando, además del material de cura, 3M Cavilon en una sección de la piel perilesional. La zona de piel perilesional en la que no se utilizó 3M Cavilon nos sirvió como control. Las úlceras fueron evaluadas por inspección visual, fotografía digital y microscopía confocal in vivo previa al uso de 3M Cavilon y a la semana de aplicación diaria del producto. Las úlceras demostraron una mejoría clínica. La evaluación con microscopía confocal de reflectancia evidenció importante mejoría histológica del área tratada con 3M Cavilon comparada con el área no tratada con este apósito. En el momento inicial del estudio, la piel perilesional demostró la presencia de áreas de necrosis epidérmicas, espongiosis, infiltración por células inflamatorias y vasodilatación prominente. Tras la semana de tratamiento, aunque todo el área de piel perilesional demostró mejoría, en el área tratada con 3M

  2. Efectividad del tratamiento de las úlceras venosas con vendaje compresivo multicapa asociado a protección de la piel perilesional con Cavilon® (película barrera no irritante Effectiveness of the association of multilayer compression therapy and periwound protection with Cavilon® (no sting barrier film in the treatment of venous leg ulcers

    Directory of Open Access Journals (Sweden)

    N. Serra

    2010-09-01

    Full Text Available Introducción: el adecuado tratamiento de las úlceras de extremidad inferior de etiología venosa es fundamental para mejorar la calidad de vida de los pacientes. El uso de terapia compresiva con vendaje multicapa es el tratamiento que mejores resultados presenta. En la práctica, se utiliza en combinación con unos adecuados cuidados locales de la herida y de la piel perilesional. El objetivo del estudio fue evaluar la efectividad clínica de un vendaje multicapa de compresión y el impacto de la utilización de la película barrera Cavilon® en úlceras vasculares de origen venoso. Metodología: ensayo clínico controlado, aleatorizado, abierto, multicéntrico y pragmático en España. Todos los pacientes incluidos fueron tratados con terapia de compresión con el mismo vendaje multicapa y asignados aleatoriamente al grupo de intervención, tratados con la PBNI Cavilon®, o al grupo control. Se realizaron un máximo de 13 visitas de estudio separadas entre ellas por una semana. El estudio fue evaluado y aprobado por los comités éticos de investigación clínica (CEIC de los siete centros participantes. Resultados: participaron 98 pacientes en el estudio (49 en el grupo intervención y 49 como control. Tras cuatro semanas, el grupo intervención presentó una reducción media (DE del tamaño de úlcera superior al grupo control (56,7% (30,3 vs. 45,5% (47,4; p = 0,087. A las 12 semanas de tratamiento, las diferencias observadas fueron estadísticamente significativas (83,4% (31,1 vs. 71,6% (44,1; p = 0,046. El 69,4% de los pacientes del grupo intervención redujo el área de úlcera en > 50% en las cuatro primeras semanas de tratamiento, respecto al 46,9% de los pacientes del grupo control (p Aim: appropriate treatment of venous leg ulcers is essential to improve the quality of life of patients. Compression therapy using multilayer bandages show to the best clinical results. In practice, it is used in combination with a suitable local care of

  3. Synthesis and elecrophysical properties of superionic conductors Li3M2(PO4)3 (M = Fe, Sc, Cr)

    International Nuclear Information System (INIS)

    Detailed study of a new class of superionic conductors Li3M2(PO4)3 (M = Fe, Sc, Cr) is conducted. Optimal conditions of synthesis and growing of monocrystals of individual compounds and solid solutions are found. Electrophysical characteristics of the matrials obtained are investigated. Effect of isomorphous substitutions in Li3M2(PO4)3 structural type on electrophysical properties is studied. 18 refs.; 10 figs.; 6 tabs

  4. MISC_0_3M_CLR_2008

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset (MISC_0_3M_CLR_2008) includes truecolor ortho imagery covering an area north and south of the VT/Canadian border. VCGI extracted the imagery from a...

  5. MISC_0_3M_CLR_2009

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset (MISC_0_3M_CLR_2009)includes truecolor ortho imagery covering the Barre-Monteplier (Capital Region) of Vermont. VCGI reprojected the imagery from its...

  6. Stephen Hawking bags big new 3m physics prize

    Science.gov (United States)

    Johnston, Hamish

    2013-01-01

    A massive 3m in prize money has gone to the British cosmologist Stephen Hawking for his work on black holes, quantum gravity and the early universe. The award is one of two "special fundamental physics prizes" from the Fundamental Physics Prize Foundation, which was set up earlier this year by the Russian physicist-turned-entrepreneur Yuri Milner.

  7. Testing of the 3M Company Composite Conductor

    Energy Technology Data Exchange (ETDEWEB)

    Stovall, John P [ORNL; Rizy, D Tom [ORNL; Kisner, Roger A [ORNL

    2010-10-01

    The 3M Company has developed a high-temperature low-sag conductor referred to as Aluminum-Conductor Composite-Reinforced or ACCR. The conductor uses an aluminum metal matrix material to replace the steel in conventional conductors. The objective of this work is to accelerate the commercial acceptance by electric utilities of this new conductor design by testing four representative conductor classes in controlled conditions. A unique facility called the Powerline Conductor Accelerated Testing (PCAT) Facility was built at ORNL for testing overhead conductors. The PCAT has been uniquely designed for testing overhead bare transmission line conductors at high currents and temperatures after they have been installed and tensioned to the manufacturer's specifications. The ability to operate a transmission line conductor in this manner does not exist elsewhere in the United States. Four classes of ACCR cable designed by the 3M Company have been successfully test at ORNL small, medium, large and small/compact. Based on these and other manufacturer tests, the 3M Company has successfully introduced the ACCR into the commercial market and has completed over twenty installations for utility companies.

  8. Hamline/3M Project: Liaison for Curricular Change

    Science.gov (United States)

    Rundquist, Andy

    2002-03-01

    This project was designed to catalyze curricular changes to better prepare students for the workplace. Industrial managers provided a list of 16 characteristics valued in the workplace: most were NOT related to science course content. The project formed 5 teams each including 3M professionals and students. Each team developed curricular changes in one of the 16 areas. Team goals were to improve skills in communication, data analysis, business/economics, team problem solving, and culture competency. Curricular changes realized include communication skill activities embodied in science courses and faculty communication teaching skill seminars, self learning tools in data analysis, statistics and model building, a new course developed with assistance from 3M personnel focussing on topics directly related to technological industries, high performance team problem solving training/coaching for faculty and workshops for students and faculty relative to importance of cultural competencies in the workplace, and a new course focusing on culture, team problem solving and conflict resolution in the technical workplace. Process for developing and content of curricular changes will be reported.

  9. Hamline/3M Corp. Project: Liason for Curricular Change*

    Science.gov (United States)

    Artz, Jerry L.

    2002-04-01

    This project was designed to catalyze curricular changes to better prepare students for the workplace. Industrial managers provided a list of 16 characteristics valued in the workplace; most were NOT related to science course content. The project formed 5 teams each including 3M professionals and students. Each team developed curricular changes in one of the 16 areas. Team goals were to improve skills in communication, data analysis, business/economics, team problem solving, and cultural competency. Curricular changes realized include communication skill activities embodied in science courses and faculty communication teaching skill seminars; self learning tools in data analysis, statistics and model building; a new course developed with assistance from 3M personnel focusing on topics directly related to technological industries; high performance team problem solving training/coaching for faculty; workshops for students and faculty relative to importance of cultural competencies in the workplace; and a new course focusing on culture, team problem solving and conflict resolution in the technical workplace. Process for developing and content of curricular changes will be reported. *Thanks to: NSF GOALI CHE-99010782

  10. 30 years of ergonomics at 3M: a case study.

    Science.gov (United States)

    Larson, N; Wick, H

    2012-01-01

    The added value of the Ergonomics Program at 3M was found to be improved employee safety, compliance with regulations and reduction of work-related illness, increases in productivity, and quality and operating efficiency. This paper describes the thirty years of existence of this program. For the first twenty years, the program objectives were to: respond to requests for assistance related to work-related musculoskeletal disorder (WMSD) concerns, raise employee awareness of MSDs and ergonomics; educate engineers in ergonomics design; and develop ergonomics teams at manufacturing locations. Since the year 2000, 3M's Ergonomics Program has been in transition from a US-centric and corporate-based technical-expertled program to a global program applying participatory ergonomics strategies within a macroergonomics framework. During that transition, the existing program requirements were revised, new methods and program tools were created, and expectations for implementation at the manufacturing locations clarified. This paper focuses on the company's manufacturing ergonomics program activities during the past ten years and includes specifics of the program's objectives, risk assessment reduction process, and ergonomics technical expertise development. The main benefit achieved throughout the company is reducing employee injury while also increasing productivity and operating efficiency.

  11. Alloying behavior of Ni3M-type GCP compounds

    International Nuclear Information System (INIS)

    The site preference of ternary additions in Ni3M-type GCP compounds was determined from the direction of solubility lobe of the GCP phase on the ternary phase diagram that have been experimentally reported. In Ni3Nb (D0a), Co and Cu preferred the substitution for Ni-site, Ti, V and W the substitution for Nb-site, and Fe the substitution for both sites. In Ni3V (D022), Co preferred the substitution for Ni-site, Cr the substitution for both sites, and Ti the substitution for V-site. In Ni3Ti (D024), Fe, Co, Cu, and Si preferred the substitution for Ni-site, Nb, Mo and V the substitution for Ti-site. The thermodynamic model, which was based on the change in total bonding energy of the host compound by a small addition of ternary solute, was applied to predict the site preference of ternary additions. The bond energy of each nearest neighbor pair used in the thermodynamic calculation was derived from the heat of compound formation by Miedema's formula. The agreement between the thermodynamic model and the result of the literature search was excellent. From both experimental and theoretical results, it was shown in three Ni3M-type GCP compounds that both transition and B-subgroup elements have two possibilities, i.e., the case of substitution for Ni-site or the case for M-site, depending on the relative value of two interaction energies.

  12. Testing of the 3M Company ACCR Conductor

    Energy Technology Data Exchange (ETDEWEB)

    Stovall, J.P.; RIzy, D.T.; Kisner, R.A.; Deve, H.E. (3M Comp.)

    2010-09-15

    The 3M Company has developed a high-temperature low-sag conductor referred to as Aluminum- Conductor Composite-Reinforced or ACCR. The conductor uses an aluminum metal matrix material to replace the steel in conventional conductors so the core has a lower density and higher conductivity. The objective of this work is to accelerate the commercial acceptance by electric utilities of these new conductor designs by testing four representative conductor classes in controlled conditions. Overhead transmission lines use bare aluminum conductor strands wrapped around a steel core strands to transmit electricity. The typical cable is referred to as aluminum-conductor steel-reinforced (ACSR). The outer strands are aluminum, chosen for its conductivity, low weight, and low cost. The center strand is of steel for the strength required to support the weight without stretching the aluminum due to its ductility. The power density of a transmission corridor has been directly increased by increasing the voltage level. Transmission voltages have increased from 115-kV to 765- kV over the past 80 years. In the United States, further increasing the voltage level is not feasible at this point in time, so in order to further increase the power density of a transmission corridor, conductor designs that increase the current carrying capability have been examined. One of the key limiting factors in the design of a transmission line is the conductor sag which determines the clearance of the conductor above ground or underlying structures needed for electrical safety. Increasing the current carrying capability of a conductor increases the joule heating in the conductor which increases the conductor sag. A conductor designed for high-temperature and lowsag operation requires an engineered modification of the conductor materials. To make an advanced cable, the 3M Company solution has been the development of a composite conductor consisting of Nextel ceramic fibers to replace the steel core and

  13. 3m vacuum ultraviolet spectrometer with optical multichanel detector

    International Nuclear Information System (INIS)

    This paper, describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT: It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate/phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the arrays is digitized by a 12-bit analog to digital converter and stored in a computer for its later analysis. The necessary software to store and display data has been developed. (Author)

  14. Neurotrophin-3 mRNA expression in rat intrafusal muscle fibres after denervation and reinnervation

    NARCIS (Netherlands)

    Copray, JCVM; Brouwer, N

    1997-01-01

    We have studied the regulation of the expression of neurotrophin-3 (NT-3) mRNA in neonatal and adult rat muscle spindles after denervation and after denervation followed by reinnervation. Denervation of the intrafusal fibres did not result in an upregulation of the NT-3 mRNA expression but decreased

  15. Modification of the Simpson moduli space M_{3m+1}(P_2) by vector bundles (I)

    CERN Document Server

    Iena, Oleksandr

    2010-01-01

    We consider the moduli space of stable vector bundles on curves embedded in P_2 with Hilbert polynomial 3m+1 and construct a compactification of this space by vector bundles. The result is a blow up of the Simpson moduli space M_{3m+1}(P_2).

  16. 3M3200型高效防尘口罩佩戴试验应用%3M3200 -efficiency dust masks to wear test application

    Institute of Scientific and Technical Information of China (English)

    周和军

    2011-01-01

    为了做好煤矿职业危害作业场所防护,杜绝煤矿职业尘肺病发病率,提升职工个体防护用品,分三个月时间在协庄煤矿、翟镇煤矿两矿进行了3M3200型高效防尘口罩全员佩戴试验,通过抽样调查得出结论:3M3200型高效防尘口罩具有阻垂效果好、体积小、重量轻、佩戴方便等特点,可以推广应用。%In order to make coal workplace occupational hazard protection, to prevent the incidence of pneumoconiosis Oeupational , improve employee personal protection products, sub - three months in the co - Mine, Mine Zhaizhen coal were the two high - efficiency dust masks, 3M 3200 full wear test', a sample survey concluded by : 3 M 3200 High - efficiency dust masks, dust with effective resistance, small size, light weight, convenient to wear, can be popularized.

  17. Digital signage sobre IP

    OpenAIRE

    Casademont Filella, Albert

    2012-01-01

    Projecte que versa sobre el disseny i la implementació d'un sistema de Digital Signage (Cartelleria Digital) sobre IP, creant un gestor que permeti controlar de forma remota tot un conjunt de petits dispositius connectats a pantalles que emeten continguts multimèdia com vídeos, imatges, feeds rss...

  18. CRM System Using PA-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    Ajay kumar

    2010-04-01

    Full Text Available In today’s business world, Customer Relationship Management has become conventional. Inspite of the unpredictable economy, CRM is being forced into corporate budgets and is believed to be the leading and initiative factor by many companies. The custom of CRM system has become mandatory. An adequate CRM system helps in acquiring new customers and increasing the value of existing customers. Datawarehouse acts as the data resource for D3M on CRM. This paper introduces the CRM based on PA-AKD and managing relationships with customers which has become the critical competition betweenorganizations. Then the structure of CRM is described with the help of D3M, discusses the procedure to Data warehouse and the significance of D3M applied to CRM. At the end, the promoting effects of D3M to individual service are presented

  19. Pengaruh Penerapan Sistem Informasi Akuntansi Terhadap Pengambilan Keputusan Pada Politeknik Unggul LP3M Medan

    OpenAIRE

    Nasir, Miftah Faridh

    2014-01-01

    The purpose of this study was to determine how the analysis of the application of information systems in the management accounting can affect decision-making at the Polytechnic Unggul LP3M Medan and to determine the accounting information system to ensure accurate decision-making in a company. Primary data were collected by interviewing management and data documenting the Polytechnic Superior LP3M Medan. The analytical method used is descriptive. Hypothesis in this study is a significa...

  20. Ultrafiltros sobre ω.

    OpenAIRE

    Mancilla Hernández, Salvador

    2012-01-01

    El objetivo del presente trabajo estudiar los ideales y filtros sobre conjuntos numerables, los que comúnmente conocemos como filtros sobre ω o ideales sobre ω. Dentro de estos, nos enfocaremos en la clase de I-ultrafiltros los cuales fueron estudiados por James Baumgartner en [11]. Y dentro de esta clase de ultrafiltros, nos concentraremos cuando I es {A ⊆ ω : n∈A g(n) < ∞}, también conocido como ideal sumable con respecto a g, donde g es una sucesión de números reales no negativ...

  1. Marketingová strategie hasících kapalin Novec firmy 3M

    OpenAIRE

    Peřina, Matěj

    2012-01-01

    This thesis is concerned with B2B market segmentation, situational analysis and proposes a markting strategy for Novec 1230 fire protection fluid marketed by 3M Česko. Firstly a marketing literature rewiev is carried out in order to uncover the most suitabe theoretical approaches to the subject at hand. Then the 3M Company and its Czech subsidiary are presented. In the methodological part there is a description of utilized methods and approaches. Data colection and analysis are executed in th...

  2. 3m Vacuum Ultraviolet Spectrometer with Optical Multichannel Detector; Espectrometro de ultravioleta de vacio de 3m provisto de sistema de deteccion optical multicanal

    Energy Technology Data Exchange (ETDEWEB)

    Martin, P.; Peraza, C.; Blanco, F.; Campos, J.

    1993-07-01

    This paper describes the design and the performance of a normal incidence vacuum ultraviolet spectrometer, for the 300-2400 A spectral range. It is provided with a multichannel detection system. The monochromator is original design and it has been built at CIEMAT. It is equipped with a 3 m concave holographic grating with 2400 grooves/mm. The multichannel detector consists of a windowless double microchannel plate / phosphor screen image intensifier, coupled by fiber optic to a 1024 elements self-scanning linear photodiode array. The output from the array is digitized by a 12-bit analog to digital converter and stored in a computer, for its later analysis. The necessary software to store and display data has been developed. (Author) 18 refs.

  3. Efficient use of electric power in corporative 3M Mexico; Uso eficiente de la energia electrica en el corporativo 3M Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Perez, Alfredo; Quinones Bonilla, Antonio S. [3M Mexico, S.A. de C.V. (Mexico); Bustos Antunez, Jorge I.; Reyes Arce, Manuel [Hines Interests, S.A. de C.V. (Mexico)

    2003-07-01

    It is not enough to count on with the state of the art technology for the daily operation of a building, the challenge is to be able to make a clear analysis and with attainable goals for the optimization of rational use of the electrical energy in the operation of intelligent buildings without affecting the comfort and productivity for users as well as the functionality and profitability for the owner. This went our base to carry out control strategies that helped the efficient use of the electrical energy, obtaining important savings without neglecting the operative part, of services and human within the property. It is thus, that 3M Mexico wanting to reach these purposes, conducted actions to improve the efficiency of the equipment in the following items: electric network, general lighting, air conditioning system, ventilation and extraction, hydropneumatic system, and sumps operation. [Spanish] No basta contar con la tecnologia de punta para la operacion diaria de un edificio, el reto es ser capaces de realizar un analisis claro y con metas alcanzables para la optimizacion de uso racional de la energia electrica en las operaciones de edificios inteligentes sin afectar el confort y productividad para usuarios asi como la funcionalidad y rentabilidad para el propietario. Esta fue nuestra base para llevar a cabo estrategias de control que ayudaron al uso eficiente de la energia electrica, obteniendo ahorros importantes sin descuidar la parte operativa, de servicios y humana dentro de la propiedad. Es asi, que 3M Mexico queriendo alcanzar dichos propositos, realizo acciones para mejorar la eficiencia de los equipos en los siguientes rubros: red electrica, iluminacion general, sistema de aire acondicionado, ventilacion y extraccion, sistema hidroneumatico, y operacion de carcamos.

  4. CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer.

    Directory of Open Access Journals (Sweden)

    Eira Valeria Barrón

    Full Text Available The cyclin-dependent kinase inhibitor 3 (CDKN3 gene, involved in mitosis, is upregulated in cervical cancer (CC. We investigated CDKN3 mRNA as a survival biomarker and potential therapeutic target for CC. CDKN3 mRNA was measured in 134 CC and 25 controls by quantitative PCR. A 5-year survival study was conducted in 121 of these CC patients. Furthermore, CDKN3-specific siRNAs were used to investigate whether CDKN3 is involved in proliferation, migration, and invasion in CC-derived cell lines (SiHa, CaSki, HeLa. CDKN3 mRNA was on average 6.4-fold higher in tumors than in controls (p = 8 x 10-6, Mann-Whitney. A total of 68.2% of CC patients over expressing CDKN3 gene (fold change ≥ 17 died within two years of diagnosis, independent of the clinical stage and HPV type (Hazard Ratio = 5.0, 95% CI: 2.5-10, p = 3.3 x 10-6, Cox proportional-hazards regression. In contrast, only 19.2% of the patients with lower CDKN3 expression died in the same period. In vitro inactivation of CDKN3 decreased cell proliferation on average 67%, although it had no effect on cell migration and invasion. CDKN3 mRNA may be a good survival biomarker and potential therapeutic target in CC.

  5. CRM System Using CM-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    I.Kali Pradeep,

    2010-03-01

    Full Text Available In the present days, the Customer Relationship Management (CRM for short system has entered into the mainstream despite the uncertainty of the economy. CRM is being trust into corporate budgets and talked about as a critical initiative by various companies. CRM is an important edge in the business world. Building an effective CRM system can get more effectively in acquiring new customers, increasing value of existing customers and retaining good customers. At the same time, the data and data warehouse will offer the best dataresource for the application of Domain Drive Data Mining (D3M for short on CRM. The managing relationships with the customer have become a critical organizational competency. In this paper we introduce CRM with the advanced technologies for getting winning strategies. Later on, we introduce the architecture of CRM based on D3M. Which involves in designing the main steps of data warehouse and also it describes the managing of D3M applied to CRM. Finally, the promoting effects of D3M to individual services are presented.

  6. Regulation of TRIB3 mRNA and Protein in Breast Cancer

    NARCIS (Netherlands)

    Wennemers, M.; Bussink, J.; Beucken, T. van den; Sweep, F.C.; Span, P.N.

    2012-01-01

    Tribbles homolog 3 (TRIB3) is a scaffold protein activated under hypoxic conditions and involved in several cell survival and proliferation pathways. Recently, we reported opposite associations of TRIB3 mRNA and protein with breast cancer prognosis. In this study, we investigated this discrepancy be

  7. Syntheses, structures, optical properties, and electronic structures of KBaMSe{sub 3} (M = As, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Yin, Wenlong [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-306 Mianyang 621900 (China); Feng, Kai; Kang, Lei [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); University of the Chinese Academy of Sciences, Beijing 100049 (China); Kang, Bin; Deng, Jianguo [Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-306 Mianyang 621900 (China); Lin, Zheshuai [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Yao, Jiyong, E-mail: jyao@mail.ipc.ac.cn [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Wu, Yicheng [Key Laboratory of Functional Crystals and Laser Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-12-25

    Graphical abstract: KBaMSe{sub 3} (M = As, Sb) are isostructural and crystallize in the centrosymmetric monoclinic space group P2{sub 1}/c with zero-dimensional structures containing totally isolated MSe{sub 3} (M = As, Sb) pyramids with K{sup +} and Ba{sup 2+} cations lying between them. - Highlights: • Two new quaternary chalcogenides KBaMSe{sub 3} (M = As, Sb) were synthesized. • They are isostructural and crystallize in the centrosymmetric space group P2{sub 1}/c. • They adopt a zero-dimensional structure containing isolated MSe{sub 3} trigonal pyramids. • The optical band gaps are 2.26 (2) eV for KBaAsSe{sub 3} and 2.04 (2) eV for KBaSbSe{sub 3}. • KBaMSe{sub 3} (M = As, Sb) are indirect band gap semiconductors. - Abstract: The first two members in the quaternary A/A′/M/Q (A = alkali metal; A′ = alkaline-earth metal; M = As, Sb, Bi; Q = S, Se, Te) system, namely the KBaMSe{sub 3} (M = As, Sb) selenides, have been synthesized by solid state reactions. They are isostructural and crystallize in the centrosymmetric space group P2{sub 1}/c of the monoclinic system. In the structure, the trivalent M atom (M = As, Sb) is coordinated to three Se atoms forming a trigonal pyramid with the Se atoms serving as the triangle base, showing the stereochemical activity of the ns{sup 2} lone pair electron. The MSe{sub 3} (M = As, Sb) trigonal pyramids are totally isolated from each other with K{sup +} and Ba{sup 2+} cations located between them. The optical band gaps of 2.26 (2) eV for KBaAsSe{sub 3} and 2.04 (2) eV for KBaSbSe{sub 3}, were deduced from the diffuse reflectance spectra. The first principles calculations were performed to study the electronic structures of KBaMSe{sub 3} (M = As, Sb) compounds and the results indicated that these two compounds are indirect band gap semiconductors.

  8. miR-155 targets Caspase-3 mRNA in activated macrophages.

    Science.gov (United States)

    De Santis, Rebecca; Liepelt, Anke; Mossanen, Jana C; Dueck, Anne; Simons, Nadine; Mohs, Antje; Trautwein, Christian; Meister, Gunter; Marx, Gernot; Ostareck-Lederer, Antje; Ostareck, Dirk H

    2016-01-01

    To secure the functionality of activated macrophages in the innate immune response, efficient life span control is required. Recognition of bacterial lipopolysaccharides (LPS) by toll-like receptor 4 (TLR4) induces downstream signaling pathways, which merge to induce the expression of cytokine genes and anti-apoptotic genes. MicroRNAs (miRNAs) have emerged as important inflammatory response modulators, but information about their functional impact on apoptosis is scarce. To identify miRNAs differentially expressed in response to LPS, cDNA libraries from untreated and LPS-activated murine macrophages were analyzed by deep sequencing and regulated miRNA expression was verified by Northern blotting and qPCR. Employing TargetScan(TM) we identified CASPASE-3 (CASP-3) mRNA that encodes a key player in apoptosis as potential target of LPS-induced miR-155. LPS-dependent primary macrophage activation revealed TLR4-mediated enhancement of miR-155 expression and CASP-3 mRNA reduction. Endogenous CASP-3 and cleaved CASP-3 protein declined in LPS-activated macrophages. Accumulation of miR-155 and CASP-3 mRNA in miRNA-induced silencing complexes (miRISC) was demonstrated by ARGONAUTE 2 (AGO2) immunoprecipitation. Importantly, specific antagomir transfection effectively reduced mature miR-155 and resulted in significantly elevated CASP-3 mRNA levels in activated macrophages. In vitro translation assays demonstrated that the target site in the CASP-3 mRNA 3'UTR mediates miR-155-dependent Luciferase reporter mRNA destabilization. Strikingly, Annexin V staining of macrophages transfected with antagomir-155 and stimulated with LPS prior to staurosporine (SSP) treatment implied that LPS-induced miR-155 prevents apoptosis through CASP-3 mRNA down-regulation. In conclusion, we report that miR-155-mediated CASP-3 mRNA destabilization in LPS-activated RAW 264.7 macrophages suppresses apoptosis, as a prerequisite to maintain their crucial function in inflammation. PMID:26574931

  9. Assessment of zenith tropospheric delay derived from UNB3m model over Asia area

    Science.gov (United States)

    Huang, Liangke; Xie, Shaofeng; Liu, Lilong; Feng, Haiyang; Jiang, Maofang

    2015-12-01

    The tropospheric delay is one of the main errors for earth observation and a variety of radio navigation technologies, and the UNB3m model can be used to calculate the zenith tropospheric delay (ZTD) without any real measured meteorological data, which taking the major changes in water vapor profiles with latitude into account, and it widely applied in Wide Area Augmentation System in America. However, there are few researches carried out on the assessment of ZTD from UNB3m model over Asia area. In this study, three years of the ZTD data observed from 56 IGS (International GNSS service) sites distributed in Asia area is used to assess the effectiveness and accuracy of ZTD calculated from UNB3m model. The results are: (1) relative to IGS observed ZTD, the bias and root mean square (RMS) for ZTD calculated from UNB3m model are -0.1 cm and 6.0 cm, respectively. Besides, the bias shows significant periodic characteristics in Asia area. (2) The bias and RMS present seasonal variations, which generally show larger values in summer months. (3) The precision of ZTD calculated from UNB3m model increases with increasing altitude or latitude, and also the bias and RMS show inconsistently in different Asia areas. At last, the best results can be achieved in inland area where presents the mean yearly RMS of 2.4 cm. These results provide a reference for the study of the tropospheric delay correction model and the applications of real-time GNSS navigation and positioning.

  10. Relevance of the ligand exchange rate and mechanism of fac-[(CO)3M(H2O)3]+ (M = Mn, Tc, Re) complexes for new radiopharmaceuticals.

    Science.gov (United States)

    Grundler, Pascal V; Helm, Lothar; Alberto, Roger; Merbach, André E

    2006-12-11

    The water exchange process on fac-[(CO)3Mn(H2O)3]+ and fac-[(CO)3Tc(H2O)3]+ was kinetically investigated by 17O NMR as a function of the acidity, temperature, and pressure. Up to pH 6.3 and 4.4, respectively, the exchange rate is not affected by the acidity, thus demonstrating that the contribution of the monohydroxo species fac-[(CO)3M(OH)(H2O)2] is not significant, which correlates well with a higher pKa for these complexes compared to the homologue fac-[(CO)3Re(H2O)3]+ complex. The water exchange rate K298ex/s(-1) (DeltaHex double dagger/kJ mol(-1); DeltaSex double dagger/J mol(-1) K(-1); DeltaV double dagger/cm3 mol-1) decreases down group 7 from Mn to Tc and Re: 23 (72.5; +24.4; +7.1) > 0.49 (78.3; +11.7; +3.8) > 5.4 x 10(-3) (90.3; +14.5; -). For the Mn complex only, an O exchange on the carbonyl ligand could be measured (K338co = 4.3 x 10(-6) s(-1)), which is several orders of magnitude slower than the water exchange. In the case of the Tc complex, the coupling between 17O (I = 5/2) and 99Tc (I = 9/2) nuclear spins has been observed (1J99Tc,17O = 80 +/- 5 Hz). The substitution of water in fac-[(CO)3M(H2O)3]+ by dimethyl sulfide (DMS) is slightly faster than that by CH3CN: 3 times faster for Mn, 1.5 times faster for Tc, and 1.2 times faster for Re. The pressure dependence behavior is different for Mn and Re. For Mn, the change in volume to reach the transition state is always clearly positive (water exchange, CH3CN, DMS), indicating an Id mechanism. In the case of Re, an Id/Ia changeover is assigned on the basis of reaction profiles with a strong volume maximum for pyrazine and a minimum for DMS as the entering ligand. PMID:17140248

  11. Todo sobre el neobarroco

    Directory of Open Access Journals (Sweden)

    Arturo Carrera

    2007-07-01

    Full Text Available Lo que hemos escuchado y atendido hasta aquí, hoy, ayer, sobre todo en la propuesta poética esbozada por Sergio Raimondi en su ensayo sobre Aldo Oliva, demuestra que las singularidades, su pasión, anulan subrepticiamente las nominaciones.Anoche en la televisión una orquesta sinfónica y un coro numeroso. Súbitamente, me hubiera gustado ser uno de esos intérpretes solitarios para sí, a pesar de la armonía, anónimos, a pesar del brillo sonoro… un violín, un triángulo… apenas… tres grillos… como ...

  12. Inferencias sobre Grafos

    OpenAIRE

    Sira M. Allende; Carlos N. Bouza

    2002-01-01

    El estudio de un juego puede ser modelado asumiendo que solo algunas partidas son observadas. Entonces el árbol del juego debe ser estimado utilizando información muestral. Similarmente ocurre al obtener información sobre el comportamiento de las decisiones tomadas por individuos muestreados sobre un árbol de decisión teórico. Al considerar una medida de probabilidad que caracterice el comportamiento de redes aleatorias se puede obtener un estimado del árbol asociado. Este problema es el anal...

  13. Mitos sobre agroecologia.

    OpenAIRE

    Canuto, João Carlos

    2011-01-01

    O presente ensaio vem a discutir alguns aspectos do discurso sobre a Agroecologia, procurando evidenciar contradições do senso comum, advindas seja de parte da comunidade leiga, dos meios de comunicação ou da comunidade científica. Coloca em debate alguns mitos sobre os sistemas agroecológicos, tais como: que sejam tecnologicamente retrógrados, de baixa produtividade, exigentes em mão-de-obra, economicamente inviáveis e “puramente ideológicos”.

  14. Ultra Barrier Topsheet Film for Flexible Photovoltaics with 3M Company

    Energy Technology Data Exchange (ETDEWEB)

    Funkenbusch, Arnold W. [3M Company, Saint Paul, MN (United States); Charles, Ruth P. [3M Company, Saint Paul, MN (United States)

    2014-12-30

    In this DOE sponsored program, 3M achieved the critical UBT features to enable durable flexible high efficiency modules to be produced by a range of customers who have now certified the 3M UBT and are actively developing said flexible modules. The specific objectives and accomplishments of the work under this program were; Scale-up the current Generation-1 UBT from 12” width, as made on 3M’s pilot line, to 1+meter width full-scale manufacturing, while maintaining baseline performance metrics (see table below); This objective was fully met; Validate service life of Generation-1 UBT for the 25+ year lifetime demanded by the photovoltaic market; Aggressive testing revealed potential failure modes in the Gen 1 UBT. Deficiencies were identified and corrective action taken in the Gen 2 UBT; Develop a Generation-2 UBT on the pilot line, targeting improved performance relative to baseline, including higher %T (percent transmission), lower water vapor transmission rate (WVTR) with targets based on what the technology needs for 25 year lifetime, proven lifetime of 25 years in solar module construction in the field, and lower cost; Testing of UBT Gen 2 under a wide range of conditions presented in this report failed to reveal any failure mode. Therefore UBT Gen 2 is known to be highly durable. 3M will continue to test towards statistically validating a 25 year lifetime under 3M funding; Transfer Generation-2 UBT from the pilot line to the full-scale manufacturing line within three years; and This objective was fully met.

  15. Florida hospital saves 5.3 M dollars by adopting principles of lean manufacturing.

    Science.gov (United States)

    2005-01-01

    Florida hospital saves 5.3M dollars by adopting principles of lean manufacturing. Surgery cancellations have been slashed from 13% of cases to less than 3%, while emergency department admissions have increased by 20%. Those are just two of the results of a quality improvement project at Lee Memorial Health System in Fort Myers, FL, that focused on using the principles of lean manufacturing to improve patient flow in the five-hospital system

  16. IGFBP3 mRNA expression in benign and malignant breast tumors

    OpenAIRE

    Ren, Zefang; Shin, Aesun; Cai, Qiuyin; Shu, Xiao-Ou; Gao, Yu-Tang; Zheng, Wei

    2007-01-01

    Introduction Most previous studies have focused on evaluating the association between circulating insulin-like growth factor binding protein 3 (IGFBP-3) levels and breast cancer risk. Emerging evidence over the past few years suggests that IGFBP-3 may act directly on mammary epithelial cells. Methods To understand the role of IGFBP-3 in breast tumorigenesis, we investigated IGFBP3 mRNA expression levels in benign and malignant breast tumors and their adjacent normal tissues using real-time qu...

  17. Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

    Directory of Open Access Journals (Sweden)

    Omofoye Oluwaseun

    2008-05-01

    Full Text Available Abstract Background IGF binding protein-3 (IGFBP-3 regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of colorectal cancer (CRC, but the role of tissue IGFBP-3 is not well defined. We evaluated the association between tissue or plasma IGFBP-3 and risk of colorectal adenomas or low apoptosis. Methods Subjects were consenting patients who underwent a clinically indicated colonoscopy at UNC Hospitals and provided information on diet and lifestyle. IGFBP-3 mRNA in normal colon was assessed by real time RT-PCR. Plasma IGFBP-3 was measured by ELISA and apoptosis was determined by morphology on H & E slides. Logistic regression was used to compute odds ratio (OR and 95% confidence intervals. Results We observed a modest correlation between plasma IGFBP-3 and tissue IGFBP-3 expression (p = 0.007. There was no significant association between plasma IGFBP-3 and adenomas or apoptosis. Tissue IGFBP-3 mRNA expression was significantly lower in cases than controls. Subjects in the lowest three quartiles of tissue IGFBP-3 gene expression were more likely to have adenomas. Consistent with previous reports, low apoptosis was significantly associated with increased risk of adenomas (p = 0.003. Surprisingly, local IGFBP-3 mRNA expression was inversely associated with apoptosis. Conclusion Low expression of IGFBP-3 mRNA in normal colonic mucosa predicts increased risk of adenomas. Our findings suggest that local IGFBP-3 in the colon may directly increase adenoma risk but IGFBP-3 may act through a pathway other than apoptosis to influence adenoma risk.

  18. Modified Foxp3 mRNA protects against asthma through an IL-10 dependent mechanism

    OpenAIRE

    Mays, Lauren E.; Ammon-Treiber, Susanne; Mothes, Benedikt; Alkhaled, Mohammed; Rottenberger, Jennifer; Müller-Hermelink, Eva Sophie; Grimm, Melanie; Mezger, Markus; Beer-Hammer, Sandra; von Stebut, Esther; Rieber, Nikolaus; Nürnberg, Bernd; Schwab, Matthias; Handgretinger, Rupert; Idzko, Marco

    2013-01-01

    Chemically modified mRNA is capable of inducing therapeutic levels of protein expression while circumventing the threat of genomic integration often associated with viral vectors. We utilized this novel therapeutic tool to express the regulatory T cell transcription factor, FOXP3, in a time- and site-specific fashion in murine lung, in order to prevent allergic asthma in vivo. We show that modified Foxp3 mRNA rebalanced pulmonary T helper cell responses and protected from allergen-induced tis...

  19. Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

    International Nuclear Information System (INIS)

    IGF binding protein-3 (IGFBP-3) regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of colorectal cancer (CRC), but the role of tissue IGFBP-3 is not well defined. We evaluated the association between tissue or plasma IGFBP-3 and risk of colorectal adenomas or low apoptosis. Subjects were consenting patients who underwent a clinically indicated colonoscopy at UNC Hospitals and provided information on diet and lifestyle. IGFBP-3 mRNA in normal colon was assessed by real time RT-PCR. Plasma IGFBP-3 was measured by ELISA and apoptosis was determined by morphology on H & E slides. Logistic regression was used to compute odds ratio (OR) and 95% confidence intervals. We observed a modest correlation between plasma IGFBP-3 and tissue IGFBP-3 expression (p = 0.007). There was no significant association between plasma IGFBP-3 and adenomas or apoptosis. Tissue IGFBP-3 mRNA expression was significantly lower in cases than controls. Subjects in the lowest three quartiles of tissue IGFBP-3 gene expression were more likely to have adenomas. Consistent with previous reports, low apoptosis was significantly associated with increased risk of adenomas (p = 0.003). Surprisingly, local IGFBP-3 mRNA expression was inversely associated with apoptosis. Low expression of IGFBP-3 mRNA in normal colonic mucosa predicts increased risk of adenomas. Our findings suggest that local IGFBP-3 in the colon may directly increase adenoma risk but IGFBP-3 may act through a pathway other than apoptosis to influence adenoma risk

  20. Customer Relationship Management System with USCM-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    Ch. Raja Ramesh

    2010-09-01

    Full Text Available Customer Relationship Management (CRM for short System emerged in the last decade to reflect the central role of the customer for the strategic positioning of a company. One of the most significant changes in the practice of marketing during the last decade is the shift in emphasis from a transaction orientation customer to the CRM. Now a day’s it is an important edge but now a necessary tool for survival. CRM competence is very important source for enterprises to build and sustain competitive advantage. With the extensive applications in CRM enterprises have plenty of customer data. Main view of CRM is customer understanding, which is properly done will helps to understand customers and thus increases customer life time value. Effectively build CRM will maintain good relationships with customers. Companies have invested or are planning to invest huge amounts to implement CRM strategies, tools and infrastructures inorder to attract and retain profitable customers in today’s increasingly competitive markets. This paper introduces the architecture of RM based on Domain Driven Data Mining (D3M for short and with advanced technologies for knowing winning strategies. Italso discusses the important steps of designing the data warehouseand describes the meaning of D3M applied to the CRM and finally evolving of D3M to individual service are presented.

  1. Localization of orphan receptor TR3 mRNA in early developmental follicles in rat

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    By in situ hybridization, the localization of orphan receptor TR3 mRNA has been observed in early developmental follicles. TR3 mRNA is first expressed in the ovarian interstitial cells on day 2 after birth, and then in granulosa cells (GC) in primary follicles on day 4. The expression level of TR3 mRNA in GC increases following the follicular development. Its higher expression can be observed in the outer layer of GC and inner layer of theca cells (TC) on day 6, where the cells present active proliferation and differentiation. The expression of TR3 is in an increasing manner until the large antral follicles on day 30. The mRNA is only expressed in the healthy, but not atretic follicles in adult rat ovaries. Injection of epidermal growth factor (EGF) has dramatically enhanced its expression in the early stage of developmental follicles. It is therefore suggested that TR3 may play a role in regulating growth and differentiation of ovarian somatic cells in the early stage, and its expression is regulated by EGF.

  2. A layered antiferromagnetic semiconductor EuMTe{sub 3} (M = Bi, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Niu, Ying Y.; Wu, Dong; Shen, Liang; Wang, Biao [State Key Laboratory of Optoelectronic Materials and Technologies, School of Physics and Engineering, Sun Yat-sen University, Guangzhou, 510275 (China)

    2015-12-15

    We synthesized ternary tellurides EuMTe{sub 3} (M = Bi, Sb) using a low-temperature flux method. These compounds crystallize in the P{sub mmn} space group with layered structure. A superstructure modulation along the b-axis was observed. Physical property measurements revealed that these compounds are antiferromagnetic semiconductors. Finally, a strong spin-orbit coupling with possible novel quantum interference between localization and weak antilocalization effects was suggested in the present system. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. Zinc finger protein TTP interacts with CCL3 mRNA and regulates tissue inflammation*

    OpenAIRE

    Kang, Ju-Gyeong; Amar, Marcelo J.; Remaley, Alan T.; Kwon, Jaeyul; Blackshear, Perry J.; Wang, Ping-yuan; Hwang, Paul M.

    2011-01-01

    Zinc finger protein tristetraprolin (TTP) modulates macrophage inflammatory activity by destabilizing cytokine mRNAs. Here, through a screen of TTP-bound mRNAs in activated human macrophages, we have identified CC chemokine ligand 3 (CCL3) mRNA as the most abundantly bound TTP target mRNA and have characterized this interaction via conserved AU-rich elements. Compared to the wild-type cells, TTP−/− macrophages produced higher levels of LPS-induced CCL3. In addition, the plasma level of CCL3 i...

  4. Study of timing characteristics of a 3 m long plastic scintillator counter using waveform digitizers

    CERN Document Server

    Blondel, A; Dubreuil, A; Khotyantsev, A; Korzenev, A; Maalmi, J; Mefodev, A; Mermod, P; Noah, E

    2016-01-01

    A plastic scintillator bar with dimensions 3 m x 2.5 cm x 11 cm was exposed to a focused muon beam to study its light yield and timing characteristics as a function of position and angle of incidence. The scintillating light was read out at both ends by photomultiplier tubes whose pulse shapes were recorded by waveform digitizers. Results obtained with the WAVECATCHER and SAMPIC digitizers are analyzed and compared. A comprehensive discussion of the various factors affecting the timing resolution is presented. Prospects for applications of plastic scintillator technology in large-scale particle physics detectors with timing resolution around 100 ps are provided in light of the results.

  5. Theoretical study of 'Mixed' ligands superhalogens: Cl-M-NO3 (M = Li, Na, K)

    Science.gov (United States)

    Zhao, Xinghua; Liu, Weihui; Wang, Jiesheng; Li, Chun; Yuan, Guang

    2016-08-01

    MCl2-, M(NO3)2-, and (Cl-M-NO3)- (M = Li, Na, K) species are systematically investigated using the density functional theory. In all the cases studied, the vertical detachment energies (VDEs) exceed the electron affinity of chlorine atom, leading to the conclusion that MCl2-, M(NO3)2- and (Cl-M-NO3)- are superhalogens. The VDEs of (Cl-M-NO3)- are between that of MCl2- and M(NO3)2-, showing that replacing one ligand with a larger electronegative ligand leads to the higher VDE. Superhalogens with suitable VDEs can be built by using different ligands.

  6. Inferencias sobre Grafos

    Directory of Open Access Journals (Sweden)

    Sira M. Allende

    2002-05-01

    Full Text Available El estudio de un juego puede ser modelado asumiendo que solo algunas partidas son observadas. Entonces el árbol del juego debe ser estimado utilizando información muestral. Similarmente ocurre al obtener información sobre el comportamiento de las decisiones tomadas por individuos muestreados sobre un árbol de decisión teórico. Al considerar una medida de probabilidad que caracterice el comportamiento de redes aleatorias se puede obtener un estimado del árbol asociado. Este problema es el analizado en este trabajo. Algunos resultados experimentales obtenidos usando Recocido Simulado ilustran el procedimiento. Su papel en el estudio de modelos económicos y de mercadeo es discutido.

  7. Estudios sobre Borges

    OpenAIRE

    Facultad de Humanidades y Ciencias de la Educación

    1991-01-01

    Contenidos de la obra: De Barthes a Pierre Menard | José Luis De Diego Pierre Menard, autor del Quijote: De la poligrafía al fraude | Andrea Cucatto Homenaje a Roberto Arlt: La otra cara de la moneda | Fabio Espósito Emma a través del espejo: Una lectura de Emma Zunz | Graciela Beatriz Goldchluk Sobre el concepto de verdad en Borges | Sergio Pastormerlo

  8. Assessment of irradiation effects on beryllium reflector and heavy water tank of JRR-3M

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, Yoji; Kakehuda, Kazuhiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-10-01

    The JRR-3M, a swimming pool type research reactor with beryllium and heavy water reflectors, has been operated since 1990. Since the beryllium reflectors are close to fuel and receive high fast neutron fluence in a relatively short time, they may be subject to change their dimensions by swelling due mostly to entrapped helium gaseous. This may bend the reflectors to the outside and narrow gaps between the reflectors and the fuel elements. The gaps have been measured with an ultrasonic thickness gage in an annual inspection. The results in 1996 show that the maximum of expansion in the diametral directions was 0.6 mm against 1.6 mm of a managed value for replacement of the reflector. A heavy water tank of the JRR-3M is made of aluminum alloy A5052. Surveillance tests of the alloy have been conducted to evaluate irradiation effects of the heavy water tank. Five sets of specimens of the alloy have been irradiated in the beryllium reflectors where fast neutron flux is higher than that in the heavy water tank. In 1994, one set of specimens had been unloaded and carried out the post-irradiation tests. The results show that the heavy water tank preserved satisfactory mechanical properties. (author)

  9. Calculation of fine neutron spectrum in irradiation holes in fuel region of JRR-3M

    International Nuclear Information System (INIS)

    The authors have a plan to evaluate TRU neutron cross sections based on the activation experiments by using JRR-3M. Fine neutron spectrum expressed by 107 energy group structure at irradiation holes in fuel region of JRR-3M core, which was utilized to analyze experimental data, was calculated by 2 step calculation. The first step is the whole core calculation taking account of burnup history and control rod pattern, and the second step is the irradiation hole calculation without any homogenization of irradiation hole components by taking into account of the neutron spectrum of surrounding region. Fine neutron spectra calculated by 2 step calculation were compared with the experimental results on reaction rate, both agreed within several percents relatively. In the comparison of absolute values, however, the maximum difference was up to 30 percents in the vicinity of control rods. This originates from the neutron transport effect around control rods. An improvement for the treatment of neutron transport effect is needed to get higher accuracy. (author)

  10. Unique Roll-Off Roof for Housing 1.3 m Telescope at Devasthal, Nainital

    Science.gov (United States)

    Bangia, Tarun

    2016-05-01

    Aryabhatta Research Institute of Observational Sciences (ARIES) had set up a 1.3 m telescope at Devasthal, Nainital, India in the year 2010. Country's largest roll-off roof was indigenously designed, fabricated and installed on top of a building (17 × 8 m) for housing 1.3 m telescope. Telescope was supplied by M/s DFM Engineering Inc., USA to ARIES and was installed in the building with unique roll-off roof to protect it from external environment. Roll-off roof was designed and fabricated considering various parameters and available manpower and resources at ARIES. This paper presents mechanical development work, simple but distinct design approach and innovative selection of materials to economically manufacture roll-off roof of large size (8 × 8 × 4 m) at hilly remote site of Devasthal situated in Central Himalayan region. All operations in the roof viz. opening of shutters and rolling of roof were motorized to facilitate observers during night observations.

  11. GRACOS: Scalable and Load Balanced P3M Cosmological N-body Code

    CERN Document Server

    Shirokov, A; Shirokov, Alexander; Bertschinger, Edmund

    2005-01-01

    We present a parallel implementation of the particle-particle/particle-mesh (P3M) algorithm for distributed memory clusters. The GRACOS (GRAvitational COSmology) code uses a hybrid method for both computation and domain decomposition. Long-range forces are computed using a Fourier transform gravity solver on a regular mesh; the mesh is distributed across parallel processes using a static one-dimensional slab domain decomposition. Short-range forces are computed by direct summation of close pairs; particles are distributed using a dynamic domain decomposition based on a space-filling Hilbert curve. A nearly-optimal method was devised to dynamically repartition the particle distribution so as to maintain load balance even for extremely inhomogeneous mass distributions. Tests using $800^3$ simulations on a 40-processor beowulf cluster showed good load balance and scalability up to 80 processes. We discuss the limits on scalability imposed by communication and extreme clustering and suggest how they may be remove...

  12. Determination of the first hydrolysis constant of Europium (3) in 3 M of ionic strength

    Science.gov (United States)

    Ramirezbernal, Maria Elena

    The first hydrolysis constant of Eu(sup 3+) has been determined at 303 K and 3 M (NaCl) ionic strength. A solvent extraction method was used, the extractant was dibenzoylmethane in benzene and di glycolate anion in the aqueous phase provided competitive complexation. The tracer solution was (sup 152m1) Eu (III) in water. The radioactive solution of europium was obtained by neutron irradiation of europium nitrate solutions at pH 3.0, in a TRIGA Mark III nuclear reactor at a neutron flux of 1 x 10(exp 13) cm(sup -2) s(sup -1). The half life of the produced isotope, (sup 152m1) Eu (9.3 h), was verified by means of a Ge H detector and no interfering radiations were observed in the spectra.

  13. Determination of the first hydrolysis constant of Europium (III) in 3 M of ionic strength

    International Nuclear Information System (INIS)

    The first hydrolysis constant of Eu3+ has been determined at 303 K and 3 M (NaCl) ionic strength. A solvent extraction method was used, the extractant was dibenzoylmethane in benzene and di glycolate anion in the aqueous phase provided competitive complexation. The tracer solution was 152m1 Eu (III) in water. The radioactive solution of europium was obtained by neutron irradiation of europium nitrate solutions at pH 3.0, in a TRIGA Mark III nuclear reactor at a neutron flux of 1 x 1013 cm-2 s-1. The half life of the produced isotope, 152m1 Eu (9.3 h), was verified by means of a Ge H detector and no interfering radiations were observed in the spectra. (Author)

  14. Characteristics of Transient Outward Potassium Channel Exposed to 3 mT Static Magnetic Field

    Institute of Scientific and Technical Information of China (English)

    LI Gang; CHENG Lijun; QIAO Xiaoyan; LIN Ling; ZHANG Lu; LI Yuanyuan

    2009-01-01

    Acutely isolated mouse hippocampai CA3 pyramidal neurons were exposed to 3 mT static magnetic field, and the characteristics of transient outward K+ channel were studied using the whole-cell patch-clamp tech-nique. The experiment revealed that the amplitude of transient outward potassium channel current was reduced. The maximum activated current densities of control group and exposure group were 163.62±20.68 pA/pF and 98.74±16.57 pA/pF(n=12, P0.05)and the slope factor of the inactivation curves from 8.69±0.80 mV to 10.87±1.02 mV(n=12, P<0.05). The results show that the static magnetic field can change the characteristics of transient outward K+ channel, and affect the physiological functions of neurons.

  15. Lattice relaxation and ferromagnetic character of (LaVO3)m/SrVO3superlattices

    Science.gov (United States)

    Schuster, Cosima; Lüders, Ulrike; Frésard, Raymond; Schwingenschlögl, Udo

    2013-08-01

    The experimental observation that vanadate superlattices (LaVO3)m/SrVO3 show ferromagnetism up to room temperature (Lüders U. et al., Phys. Rev. B, 80 (2009) 241102(R)) is investigated by means of density functional theory, and the band structure for m = 5 and 6 is calculated. A buckling of the interface VO2 layers is found in both cases, but subtle differences in bond length lead to very different properties for even and odd values of m: in the even case, the two interface VO2 layers effectively decouple from the adjacent LaO layers due to a strong bond length enhancement. This results into a local inversion of the orbital occupancy and to the confinement of the charge carriers. In the odd case, the amplitude of the bond length variation is smaller, so that the charge carriers spill into the deeper-lying VO2 layers, and spin-polarised interfaces are obtained.

  16. 嵌入式工控机系统ARK-6310-3M04E

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    研华科技近期推出嵌入式工控机系统ARK-6310—3M04E,该产品配有Intel。ATOM处理器、Intel 945GSE芯片组和集成Mini—ITX母板,采用无风扇设计,可在恶劣环境中无噪声并可靠工作。该款紧凑、坚固型工业系统集成在一个多功能嵌入式机箱中,超紧凑的坚固构造,坚固的耳柄允许用户方便移动设备,扩展性能强,

  17. 3M:促进技术创新践行本土责任

    Institute of Scientific and Technical Information of China (English)

    马亮

    2009-01-01

    @@ 对3M而言,创新是,而且一直是,3M 最厉害的秘密致命武器. 此次EP展上,除了冷缩技术附件等传统优势产品,3M还重点展示了两款新品,即2008年12月正式登陆中国市场的加强型复合铝芯架空导线ACCR以及2009年4月推出的顺应国家环保大势的无机材料绝缘纸,使得3M在中国的产品范围从配电领域延伸到了输电领域及电力设备制造业.

  18. Preparation of Solid Strong Acid Catalysts S2O2-8/ZrO2-Al2O3-M2O3(M=Cr,Ce,La)%固体强酸催化剂S2O2-8/ZrO2-Al2O3-M2O3(M=Cr,Ce,La)的制备

    Institute of Scientific and Technical Information of China (English)

    但悠梦

    2002-01-01

    @@ 固体强酸具有酸强度高,不腐蚀设备,不污染环境,与产物分离方便等特点,是一种对环境友好的催化剂. 业已发现固体强酸对许多重要的有机反应如烃类异构化、傅克酰基化、傅克烷基化、酯化、缩合、聚合、氧化等具有良好的催化活性,可替代传统的浓H2SO4及AlCl3、HF等高污染催化剂. 在前文[1]基础上,本文通过添加Cr2O3、Ce2O3和La2O3对催化剂S2O2-8/ZrO2-Al2O3改进后制备出S2O2-8/ZrO2-Al2O3-M2O3(M=Cr,Ce,La)系列固体强酸催化剂,用对乙酸和正丁醇的酯化转化率评价了催化活性,用XRD、BET、流动Hammett指示剂法和化学分析法分别表征了催化剂的晶型结构、比表面积、酸强度和硫含量,证实了催化剂对酯化反应具有良好的催化活性和重复使用性.

  19. Informe APEI sobre movilidad

    OpenAIRE

    Arroyo Vázquez, Natalia

    2011-01-01

    Este informe incluye una amplia aproximación al concepto de movilidad, desde un punto de vista introductorio, que nunca antes en nuestro ámbito había abarcado todos los aspectos que tienen que ver con él, desde cuestiones técnicas como los dispositivos móviles, sistemas operativos y navegadores, conectividad y estándares —cuya intención es poder comprender todos aquellos aspectos relacionados con la movilidad y que tienen una incidencia directa sobre los contenidos— hasta otras más relacionad...

  20. Apuntes sobre liderazgo

    OpenAIRE

    Contreras, Manuel E.

    2010-01-01

    Este trabajo presenta una breve síntesis de las principales teorías de liderazgo y se centra sobre el enfoque de liderazgo adaptativo de Ronald Heifetz. El documento originalmente fue desarrollado para las sesiones de educación a distancia de INDES. Ha sido revisado para usar en otros ámbitos de capacitación y ha sido utilizado en sesiones presenciales llevadas a cabo por INDES, como por otras entidades en universidades y centros de capacitación de America Latina.

  1. Sobre el razonamiento judicial

    OpenAIRE

    Asís Roig, Rafael de

    1998-01-01

    El trabajo elabora modelos a través de los cuáles es posible reconstruir la argumentación judicial plasmada en las sentencias y, a la vez, hacer explícitas las reglas que sirven de justificación a sus decisiones, y el marco normativo utilizado como referencia. El estudio analiza tanto los pronunciamientos sobre hechos como los que se refieren a la calificación jurídica, en principio, desde una perspectiva descriptiva. Ahora bien, también se llevan a cabo reflexiones y propuestas que van más a...

  2. Puente sobre el Rin

    Directory of Open Access Journals (Sweden)

    Gortz, Wilhelm

    1961-12-01

    Full Text Available Del total de 35 proyectos presentados al concurso del puente para carretera sobre el Rin, entre Duisburg-Ruhrort y Homberg, sólo dos proposiciones de la Demag fueron consideradas: Una con tablero suspendido por vientos que parten de dos torres, y otra, con suspensión por cables flexibles que se apoyan en dos torres y anclaje en la misma estructura. Por razones netamente estéticas fue elegida la propuesta Demag de puente suspendido por cables, aunque la solución con vientos hubiera sido la más económica, teniendo en cuenta las condiciones existentes.

  3. Sobre la tragedia griega

    Directory of Open Access Journals (Sweden)

    Mauricio Vélez Upegui

    2015-01-01

    Full Text Available Luego de caracterizar la tragedia griega clásica como expresión de un arte ciudadano que participa por igual de un carácter festivo, cierto régimen discursivo y una clara inscripción físico-espacial, el texto se demora en considerar tres aspectos fundamentales de esta forma dramática inventada por los griegos, a saber: una exposición sobre las fuentes orales míticas de las que los autores echan mano para componer la historia de cada una de las piezas que son llevadas a escena al amparo de un espíritu agonal; una explicación del funcionamiento formal de la tragedia, basado en la alternancia de partes cantadas (coro y partes recitadas (héroe; y, finalmente, una acotación sobre el sentido –interno y externo– que la acción dramática posee, en tanto elemento articulador de la trama.

  4. Sobre historia mundial hoy

    Directory of Open Access Journals (Sweden)

    Vera Weiler

    2010-08-01

    Full Text Available Los procesos de globalización son una realidad; su enorme impacto sobre la vida humana los ha convertido en un tema recurrente sobre el que se escribe y se comenta a diario también en Colombia. Los libros que de ellos tratan, ante todo los que 10 hacen en tono crítico, baten records en la industria editorial en todo el mundo. Las expectativas que acerca del futuro abrigan cientos de millones de personas se relacionan con 10 que ellas esperan, para bien o para mal, de la globalización. Las posturas que los gobernantes ocupan al respecto en el mundo son, cuando menos de aceptación, generalmente de activa participación en pos de la globalización. Por un lado, crece la preocupación y se multiplican las protestas; por el otro, dominan los razonamientos de los especialistas en materia de maximización de los rendimientos de los capitales que presentan la globalización, al estilo que se viene imponiendo, como el camino ineludible del gobierno universal de la eficiencia. ¿Tienen que decir algo los historiadores frente a todo esto?.

  5. Subproject plan for demonstration of 3M technology for treatment of N Basin water

    International Nuclear Information System (INIS)

    A dissolved radionuclides removal demonstration is being conducted at the 105-N Basin as part of the 100-N Area Projects' policy of aggressively integrating innovative technologies to achieve more cost effective, faster, and/or safer deactivation operations. This subproject plan demonstrates new technology (marketed by the 3M trademark Company) that absorbs specific ions from water. The demonstration will take place at the spent fuel basin at the N Reactor facility. The 105-N Basin contains 1 million gal of water consisting of approximately 32 Ci of dissolved 90Sr at a concentration of 8.4 uCi/L and 7.3 Ci of dissolved 137Cs at a concentration of 1.92 uCi/L. The Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement [Ecology et al. 1990]) Milestone M-16-01E-T2 requires the initiation of pretreatment and removal of all N Reactor fuel storage basin waters by September 30, 1996, pursuant to the N Reactor Deactivation Program Plan (WHC 1993). 105-N Basin dewatering is on the critical path for overall deactivation of N Reactor by March 1997. The 105-N Basin Deactivation Program Plan (BHI 1995) includes removing debris, hardware, algae and sediment from the basin, followed by pretreatment (filtration) and removal of the 1005-N Basin water. Final water removal is currently scheduled for September 30, 1996. The recommended method of the 105-N Basin water is the treatment of the water at the Effluent Treatment Facility (ETF) in the 200 East Area. The demonstration of the 3M technology could be a feasible treatment alternative to the ETF if the ETF is not available to meet the project schedule or if additional pretreatment is needed to reduce the inventory of radioactive species to be handled at the ETF. Demonstration of this technology could be of value for other fuel basins at the Hanford Site and possibly other US Department of Energy (DOE) sites and non- DOE nuclear power plants

  6. GRACOS: Scalable and Load Balanced P3M Cosmological N-body Code

    Science.gov (United States)

    Shirokov, Alexander; Bertschinger, Edmund

    2010-10-01

    The GRACOS (GRAvitational COSmology) code, a parallel implementation of the particle-particle/particle-mesh (P3M) algorithm for distributed memory clusters, uses a hybrid method for both computation and domain decomposition. Long-range forces are computed using a Fourier transform gravity solver on a regular mesh; the mesh is distributed across parallel processes using a static one-dimensional slab domain decomposition. Short-range forces are computed by direct summation of close pairs; particles are distributed using a dynamic domain decomposition based on a space-filling Hilbert curve. A nearly-optimal method was devised to dynamically repartition the particle distribution so as to maintain load balance even for extremely inhomogeneous mass distributions. Tests using 800(3) simulations on a 40-processor beowulf cluster showed good load balance and scalability up to 80 processes. There are limits on scalability imposed by communication and extreme clustering which may be removed by extending the algorithm to include adaptive mesh refinement.

  7. 3M Petrifilm enterobacteriaceae count plate method for enumeration of enterobacteriaceae in selected foods: collaborative study.

    Science.gov (United States)

    Silbernagel, Karen M; Lindberg, Kathryn G

    2003-01-01

    The practice of detecting and enumerating all oxidase-negative, glucose-fermenting-Gram-negative rods (i.e., the family Enterobacteriaceae) is used to indicate unsanitary or inadequate food processing conditions. The objective of this interlaboratory collaborative study was to evaluate and compare the methods described in Standard Methods for the Examination of Dairy Products (SMEDP) and the Compendium of Methods for the Microbiological Examination of Foods (Compendium) with a commercial product, the 3M Petrifilm Enterobacteriaceae Count Plate, for the recovery of Enterobacteriaceae in foods. Six foods--cheddar cheese, milk, flour, frozen prepared meals, frozen broccoli, and nut pieces--were analyzed for Enterobacteriaceae by 12 collaborating laboratories. For each food tested, the collaborators received 8 blind test portions consisting of a control test portion and 3 levels of inoculated test portion, each in duplicate. Each test portion was tested by the Petrifilm Enterobacteriaceae Count Plate method as well as the SMEDP or Compendium methods. The precision estimates (repeatability or within-laboratory variation, and reproducibility or between-laboratory variation) were calculated with standard statistical techniques.

  8. Oxidation, Reduction, and Condensation of Alcohols over (MO3)3 (M=Mo, W) Nanoclusters

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Zongtang; Li, Zhenjun; Kelley, Matthew S.; Kay, Bruce D.; Li, Shenggang; Hennigan, Jamie M.; Rousseau, Roger J.; Dohnalek, Zdenek; Dixon, David A.

    2014-10-02

    The reactions of deuterated methanol, ethanol, 1-propanol, 1-butanol, 2-propanol, 2-butanol and t-butanol over cyclic (MO3)3 (M = Mo, W) clusters were studied experimentally with temperature programmed desorption (TPD) and theoretically with coupled cluster CCSD(T) theory and density functional theory. The reactions of two alcohols per M3O9 cluster are required to provide agreement with experiment for D2O release, dehydrogenation and dehydration. The reaction begins with the elimination of water by proton transfers and forms an intermediate dialkoxy species which can undergo further reaction. Dehydration proceeds by a β hydrogen transfer to a terminal M=O. Dehydrogenation takes place via an α hydrogen transfer to an adjacent MoVI = O atom or a WVI metal center with redox involved for M = Mo and no redox for M = W. The two channels have comparable activation energies. H/D exchange to produce alcohols can take place after olefin is released or via the dialkoxy species depending on the alcohol and the cluster. The Lewis acidity of the metal center with WVI being larger than MoVI results in the increased reactivity of W3O9 over Mo3O9 for dehydrogenation and dehydration.

  9. Magnetic properties and specific heat of MPS3 (M=Mn, Fe, Zn)

    International Nuclear Information System (INIS)

    The magnetic properties and specific heat of MPS3 (M=Mn, Fe and Zn) have been investigated. While ZnPS3 is non-magnetic, MnPS3 and FePS3 are antiferromagnets with the Neel temperature TN of 78 and 118 K, respectively. Nevertheless, the specific heat of MnPS3 and FePS3 is smaller than that of ZnPS3 below about 20 K. The temperature dependence of the magnetic specific heat CM of MnPS3 shows a broad hump which is characteristic to the two dimensional magnetic materials and a small sharp peak at TN. On the other hand, that of FePS3 shows a large sharp peak at TN. As for FePS3, the temperature dependences of the magnetization M and CM are well reproduced by taking account of the magneto-elastic effect which introduces an additional term proportional to the square of the average value of the spin to the exchange coupling constant. As for MnPS3, marked two dimensional characters appear in the temperature dependence of M and CM. The observed TN is much smaller than the paramagnetic Curie temperature of 240 K obtained from the temperature dependence of the magnetic susceptibility at high temperature

  10. Study of internal transport barriers in the initial phase of Ohmic discharges in TUMAN-3M

    Energy Technology Data Exchange (ETDEWEB)

    Askinazi, L G [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Bulanin, V V [St Petersburg State Polytechnical University, 195251 (Russian Federation); Vildjunas, M I [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Golant, V E [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Gorokhov, M V [St Petersburg State Polytechnical University, 195251 (Russian Federation); Kornev, V A [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Krikunov, S V [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Lebedev, S V [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Petrov, A V [St Petersburg State Polytechnical University, 195251 (Russian Federation); Rozhdestvensky, V V [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Tukachinsky, A S [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation); Zhubr, N A [Ioffe Physico-Technical Institute, RAS, 194021, St Petersburg (Russian Federation)

    2004-05-01

    A regime with electron heat confinement improvement was recently found in the initial phase of discharges in the TUMAN-3M tokamak. An internal transport barrier (ITB) formation in this regime was confirmed by Thomson scattering measurements and by transport modelling. Two possible reasons for the ITB formation are discussed in the paper: by reduction of turbulent transport in the presence of low magnetic shear or by plasma sheared rotation. It is demonstrated that low magnetic shear formation is possible in the current ramp-up phase of the Ohmic discharge. The low magnetic shear does not seem to be the only reason for the transport reduction. Results of Doppler reflectometry measurements of poloidal rotation of density fluctuations are presented. It is found that core confinement improvement correlates with the appearance of sheared rotation of the density fluctuations and with a burst of the MHD activity. The ITB formation in the regime seems to be a result of a combined action of reduced magnetic shear and plasma sheared rotation.

  11. Lattice relaxation and ferromagnetic character of (LaVO3) m/SrVO3superlattices

    KAUST Repository

    Schuster, Cosima B.

    2013-08-01

    The experimental observation that vanadate superlattices (LaVO 3)m/SrVO3 show ferromagnetism up to room temperature (Lüders U. et al., Phys. Rev. B, 80 (2009) 241102(R)) is investigated by means of density functional theory, and the band structure for m = 5 and 6 is calculated. A buckling of the interface VO2 layers is found in both cases, but subtle differences in bond length lead to very different properties for even and odd values of m: in the even case, the two interface VO2 layers effectively decouple from the adjacent LaO layers due to a strong bond length enhancement. This results into a local inversion of the orbital occupancy and to the confinement of the charge carriers. In the odd case, the amplitude of the bond length variation is smaller, so that the charge carriers spill into the deeper-lying VO2 layers, and spin-polarised interfaces are obtained. © Copyright EPLA, 2013.

  12. $P^{3}M-SPH$ simulations of the Lyman-$\\alpha $ Forest

    CERN Document Server

    Theuns, T; Efstathiou, G P; Pearce, F R; Thomas, P A; Theuns, Tom; Leonard, Anthony; Efstathiou, George

    1998-01-01

    (Abridged) We investigate the importance of several numerical artifacts such as lack of resolution on spectral properties of the Lyman alpha forest as computed from cosmological hydrodynamic simulations in a standard cold dark matter universe. We assume an ionising background produced by quasars as computed by Haardt & Madau. We use a new simulation code based on P3M and SPH, which we compare in detail with a modified version of HYDRA (Couchman et al.) and published results of TREESPH (Hernquist et al.). The agreement is very good between all three codes. We then use our new code to investigate several numerical effects such as resolution on spectral statistics deduced from Voigt profile fitting. Our highest resolution simulation has a mass resolution of 2.1x10^5 solar masses. The column density distribution is converged but the b-parameter distribution is only marginally converged. The simulation reproduces both the HI column density and b-parameter distribution when we assume a high baryon density, Omeg...

  13. Theoretical studies of the paramagnetic perovskites MTaO{sub 3} (M = Ca, Sr and Ba)

    Energy Technology Data Exchange (ETDEWEB)

    Ali, Zahid, E-mail: zahidf82@gmail.com [Center for Computational Materials Science, University of Malakand, Chakdara, Dir (Lower) (Pakistan); Khan, Imad; Ahmad, Iftikhar; Khan, M. Salman [Center for Computational Materials Science, University of Malakand, Chakdara, Dir (Lower) (Pakistan); Asadabadi, S. Jalali [Department of Physics, Faculty of Science, University of Isfahan, Hezar Gerib Avenue, Isfahan, 81744 (Iran, Islamic Republic of)

    2015-07-15

    In the present density functional studies, structural, mechanical and magneto-electronic properties of CaTaO{sub 3,} SrTaO{sub 3} and BaTaO{sub 3} perovskites have been investigated. The calculated structural parameters by DFT and analytical methods are found consistent with the experiments. The analytically calculated tolerance factors of these compounds as well as their mechanical properties show that they are stable in the cubic phase. Furthermore elastic properties show that these materials are ductile in nature and confirm that BaTaO{sub 3} is harder than the rest compounds. The calculated spin dependent magneto-electronic properties reveal the paramagnetic metallic nature of these compounds. The electrical conductivity curve demonstrates significant conductivity above room temperature. On the basis of the presented properties it is expected that these compounds could be efficient electrode materials and need experimental investigations. - Highlights: • MTaO{sub 3} (M = Ca, Sr and Ba) perovskites are investigated theoretically in the frame work of density functional theory. • Mechanical properties explain the stability of these compounds and show that BaTaO{sub 3} is more ductile. • The magneto-electronic studies reveal the paramagnetic metallic nature of these compounds. • Significant electrical conductivity is observed above room temperature.

  14. CRM System Using UI-AKD Approach of D3M

    Directory of Open Access Journals (Sweden)

    J.N.V.R.Swarup kumar,

    2010-03-01

    Full Text Available Customer Relationship Management has entered the mainstream. Despite the uncertainty of the economy, CRM is being thrust into corporate budgets and talked about as a critical initiative by numerous of companies. It has gone from being an important edge in the business world to a necessary tool for survival. Building an effective CRM system can get more effectively in acquiring new customers, increasing value of existing customers and retaining good customers. At the same time, the data of data warehouse will offer the best dataresource for the application of Domain Driven Data Mining (D3M for short on CRM. This paper introduces CRM and managing relationships with customers has become a critical organizational competency. Get winning strategies with the latent advanced technologies. Then ntroduces the architecture of CRM based on Domain Driven Data Mining, discusses the main steps of designing the Data warehouse and describes the meaning of Domain Driven Data Mining applied to CRM. Atlast, the promoting effects of Domain Driven Data Mining to individual service are presented .

  15. Astrometric and Photometric Accuracy of the 1.3 m Robotically Controlled Telescope on Kitt Peak

    Science.gov (United States)

    McGruder, Charles H.; Carini, M. T.; Engle, S. G.; Gelderman, R.; Guinan, E. F.; Laney, D.; Strolger, L.; Treffers, R. R.; Walter, D. K.

    2014-01-01

    The 1.3 m (50 inch) telescope on Kitt Peak has been refurbished and provided with an autonomous scheduler. It is operated by The Robotically Controlled Telescope (RCT) consortium whose members are: South Carolina State, Villanova and Western Kentucky Universities. The facility possesses 5 board (UBVRI) and 11 narrow-band filters. Attached to the RCT camera is a 2048 x 2048 SITe SI-424A back-illuminated CCD with 24 micrometer pixels. We used over 7,000 star measurements from 37, 198s R-images to compute the astrometric and photometric accuracy. The difference of the J2000 coordinates computed from the RCT images and the J2000 Nomad catalog coordinate values in right ascension peaks at 0.058”, while the declination peaks at -0.125”. We obtained these astrometric results using the simplest assumptions: linear relationship between standard coordinates and measured coordinates, no color or magnitude dependency and no differential refraction (all images taken in the zenith). We express the photometric accuracy in the following manner: The Signal-to-Noise-Ratio as a function of apparent magnitude shows that the RCT is not noise dominated at m < 20 magnitude.

  16. KEPADATAN JENTIK Aedes aegypti SEBAGAI INDIKATOR KEBERHASILAN PEMBERANTASAN SARANG NYAMUK (3M PLUS: DI KELURAHAN SRONDOL WETAN, SEMARANG

    Directory of Open Access Journals (Sweden)

    Bhinuri

    2008-06-01

    Full Text Available Aedes aegypti larva density as an indicator of the success in mosquito breeding place irradication in East Srondol village, Semarang. Interventions have been done to reduce DHF incidence, such as fogging and suggestion to do 3 M plus, but ABJ (larva’s number of Semarang is still under the target. The best intervention is by doing 3M plus. The aims of this research are to know the relation between social characteristics, knowledge, and attitude with the habitual elimination 3 M Plus of mosquito sites, the relation between the habitual elimination 3 M Plus of mosquito sites with larva density, the larva density and also the prediction model of larva density from the habitual elimination 3 M Plus of mosquito sites. The research has been done at Kelurahan Srondol Wetan, with observational, quantitative, and explanatory research by using cross-sectional survey method. The population were the houses with the respondent-the person who did the habitual elimination 3 M Plus of mosquito sites. Sample number were 188 with stratified random sampling. The statistic test was the Kendalls Tau and multiple regresion. The result showed that there are relation between social characteristics such as education, family number, job, and salary, with the habitual elimination 3 M Plus of mosquito sites but there is no relation with age, knowledge and attitude. There are also relations between the habitual elimination 3 M Plus of mosquito sites at bath tub, water tub and also bucket with the larva density. Based on those results, Health Department of Semarang especially Community Health Center in Srondol Wetan expected to do health education about 3 M Plus at bath tub, bucket and water tub. Suggestion also addressed to the next researcher to use purposive sampling and water storage classification for the same research.

  17. Voz sobre frame relay

    OpenAIRE

    D´Elia, Gabriel Anibal

    2000-01-01

    Esta tesis trata el tema de VOFR, desde la digitalización de la voz hasta su transmisión a través de dicha red, así también como la comparación con otros medios de transporte como VOIP. Dada las características del protocolo frame relay y su disponibilidad se eligió como el medio más apropiado para la transmisión de voz y datos en forma integrada sobre una misma red. El trabajo comienza con una breve explicación de la voz, su digitalización y forma actual de transmisión a través de una red di...

  18. Excertos sobre o sedentarismo

    Directory of Open Access Journals (Sweden)

    Alexandre Palma

    2014-09-01

    Full Text Available O sedentarismo tem sido tratado como algo perfeitamente determinável, objetivo e, portanto, que pode ser apreendido. Por outro lado, o conceito de sedentarismo ainda permanece questionável e, por conseguinte, os instrumentos mostram-se inconsistentes. Neste sentido, o objetivo do presente estudo foi mostrar que diferentes discursos de verdade vêm concorrendo por esse conceito, o que nos motiva a pensar qual é a verdade ou, até mesmo, se há alguma verdade sobre ele. Após apresentarmos diferentes possibilidades de compreender o sedentarismo, através do uso de aforismos, entendemos que postular um discurso como verdade talvez apenas signifique que as pessoas nele creem e que há uma vontade de verdade como uma vontade voltada para o poder.

  19. ErbB3 mRNA leukocyte levels as a biomarker for major depressive disorder

    Directory of Open Access Journals (Sweden)

    Milanesi Elena

    2012-09-01

    Full Text Available Abstract Background In recent years, the identification of peripheral biomarkers that are associated with psychiatric diseases, such as Major Depressive Disorder (MDD, has become relevant because these biomarkers may improve the efficiency of the differential diagnosis process and indicate targets for new antidepressant drugs. Two recent candidate genes, ErbB3 and Fgfr1, are growth factors whose mRNA levels have been found to be altered in the leukocytes of patients that are affected by bipolar disorder in a depressive state. On this basis, the aim of the study was to determine if ErbB3 and Fgfr1 mRNA levels could be a biomarkers of MDD. Methods We measured by Real Time PCR ErbB3 and Fgfr1 mRNA expression levels in leukocytes of MDD patients compared with controls. Successively, to assess whether ErbB3 mRNA levels were influenced by previous antidepressant treatment we stratified our patients sample in two cohorts, comparing drug-naive versus drug-free patients. Moreover, we evaluated the levels of the transcript in MDD patients after 12 weeks of antidepressant treatment, and in prefrontal cortex of rats stressed and treated with an antidepressant drug of the same class. Results These results showed that ErbB3 but not Fgfr1 mRNA levels were reduced in leukocytes of MDD patients compared to healthy subjects. Furthermore, ErbB3 levels were not affected by antidepressant treatment in either human or animal models Conclusions Our data suggest that ErbB3 might be considered as a biomarker for MDD and that its deficit may underlie the pathopsysiology of the disease and is not a consequence of treatment. Moreover the study supports the usefulness of leukocytes as a peripheral system for identifying biomarkers in psychiatric diseases.

  20. Synthesis of LaMO3 (M = Fe, Co, Ni) using nitrate or nitrite molten salts

    International Nuclear Information System (INIS)

    Research highlights: → The molten salt, synthesis temperature, the oxidising properties, the basicity and oxidation states of the melt play an important role in LaMO3 synthesis. → The system needs a careful optimisation of these parameters to obtain pure orthorhombic LaFeO3, hexagonal LaCoO3 and LaNiO3. Purely hexagonal LaNiO3 nanocrystals were successfully synthesized. → SEM analyses were taken to investigate how the different parameters affect the microstructure of the samples. → The specific surface area and crystallite size of LaMO3 show much difference in different system. - Abstract: Perovskite compound LaMO3 (M = Fe, Co, Ni) nanocrystals were successfully synthesized in molten nitrates or nitrites from a mixture of lanthanum nitrate and an M-containing nitrate for 2 h. The effect of the various process parameters on the phase purity, crystallite size, specific surface area and morphology of the synthesized nanocrystals were systematically studied by XRD, scanning electron microscopy (SEM), simultaneous TG/DSC and BET measurements. The results showed that salt medium, annealing temperatures (mainly 450-850 oC), oxidising properties and basicity of the melt played an important role in the synthesis of LaMO3. The addition of Na2O2 facilitated the reaction between La2O3 and NiO or Co3O4, leading to the formation of LaNiO3 and LaCoO3 at a much lower temperature of 450 oC. Pure hexagonal LaNiO3 nanocrystals were obtained in molten NaNO3-KNO3 eutectic with Na2O2 at 550-750 oC.

  1. Forkhead box protein 3 mRNA expression in the peripheral blood of kidney-transplant recipients with acute rejection

    Institute of Scientific and Technical Information of China (English)

    WANG Wei; LI Xiao-bei; YANG Xiao-yong; ZHANG Xiao-dong

    2011-01-01

    Background Regulatory T cells (Tregs) are immunologically and clinically interesting not least because of the important role they play in allograft rejection. Likewise, expression of the transcription factor forkhead box protein 3 (FOXP3), detected in transplant biopsies, is also of interest because of its role in the development of regulatory T cells. In this study, we Investigated the relationship between FoxP3 mRNA expression and acute organ rejection in kidney-transplant recipients.Methods In this prospective study, FoxP3 mRNA expression levels in peripheral blood samples from 10 recipients of living relative-donor kidney transplants were measured before transplantation as well as at the 14th and 90th days post-transplantation. In addition, 46 first-time kidney-transplant recipients participated in a cross-sectional study, with 28 patients classified as having acute organ rejection; whilst the remaining 18 patients had functionally stable allografts. FoxP3 mRNA expression levels in peripheral blood samples were compared between these two different groups.Results Before transplantation mean FoxP3 mRNA levels vs. GADPH mRNA levels (lg(FoxP3 mRNA/GADPH mRNA)) in the 10 recipients were 1.11±0.67. The mean FoxP3 mRNA expression levels measured at 14th and 90th days post-transplantation were significantly higher than before transplantation (1.69±0.38, P=0.03; 1.44±0.21, P=0.04, respectively). Additionally, the mean FoxP3 mRNA levels vs. GADPH mRNA expression levels (lg(FoxP3 mRNA/GADPH mRNA)) were significantly higher in recipients suffering acute rejection compared with those with stable allografts (1.77±0.61 and 1.43±0.27, respectively, P=0.03).Conclusions After kidney transplantation, FoxP3 mRNA levels were found to increase in the peripheral blood of all recipients. Considerably higher FoxP3 mRNA levels were observed in recipients suffering acute rejection. These results suggest that FoxP3 mRNA levels in peripheral blood samples can be used as a diagnostic

  2. Error analysis for CO and CH4 total column retrievals from SCIAMACHY 2.3 ?m spectra

    OpenAIRE

    Aben, I.; O. P. Hasekamp; Schrijver, H.; Gloudemans, A. M. S.

    2008-01-01

    International audience A detailed sensitivity analysis of the Iterative Maximum Likelihood Method (IMLM) algorithm and its application to the SCIAMACHY 2.3 ?m spectra is presented. The sensitivity analysis includes a detailed assessment of the impact of aerosols in the 2.3 ?m range. Results show that near strong aerosol sources mineral dust and biomass aerosols can have an effect of ~7?10% on the CH4 total columns retrieved from this wavelength range. Similar but somewhat larger effects ar...

  3. Tumor Necrosis Factor-related Apoptosis Ligand Induces Apoptosis in Prostate Cancer PC-3M Cell Line

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhohui; WANG Huafang; GU Longjie; YE Zhewei; XIAO Yajun

    2005-01-01

    To study the effect of tumor necrosis factor-related apoptosis inducing ligand (TRAIL)on PC-3M cell line, PC-3M cell line was incubated with gradient concentrations of TRAIL for 4-24h. Annixin-Ⅴ fluorescence staining and TUNEL method were employed to detect the apoptosis of PC-3M cells. The morphology of apoptotic PC-3M cells was observed by electron microscopy. The relationship between TRAIL concentrations and the percentage of apoptotic cells was evaluated by flow cytometry. The proliferation inhibitory ratio was calculated by using MTT colorimetry. Our results showed that apoptosis of PC-3M cells could be induced by treatment with TRAIL for at most 4 h. The results of flow cytometry and MTT colorimetry demonstrated a time- and concentration-dependent relationship between cell apoptosis rate and TRAIL concentration. It is concluded that apoptosis of PC-3M cells can be induced by TRAIL. Because of the selective killing effect of TRAIL on tumor ceils, it may become a potential alternative for the treatment of advanced prostate cancer.

  4. In vivo left ventricular assist induced coagulation derangements. Comparison of Sarns-3M and St. Jude Medical circuits.

    Science.gov (United States)

    Curtis, J J; Wagner-Mann, C C; Mann, F A; Demmy, T L; Walls, J T; Schmaltz, R A

    1997-01-01

    An in vitro comparison of centrifugal pumping systems manufactured by Sarns-3M and St. Jude Medical revealed a difference in blood cell derangement. The purpose of this study was to compare in vivo the effects of 96 hr of left ventricular assist (LVA) on indexes of coagulopathy, hemolysis, and complement activation. Two groups of calves (each: n = 5) were instrumented with identical left atrial to thoracic aorta centrifugal pumping circuits using either Sarns-3M or St. Jude centrifugal pumps. Laboratory evaluations were performed pre-assist and at 1, 4, 24, 48, 72, and 96 hr during LVA. Platelet counts dropped significantly by 24 hr (Sarns-3M: 28%; St. Jude: 30%); no significant change in function was noted. Activated clotting time increased slightly (p > 0.05). Prothrombin time increased at 4 and 24 hr of LVA, returning to baseline by 96 hr (p Sarns-3M device never reached significance. No significant changes in lactate dehydrogenase or plasma free hemoglobin were detected. Complement fraction C5a rose by 1 hr of LVA (p Sarns-3M and St. Jude LVA caused coagulation derangement in calves, 2) neither pump demonstrated an advantage regarding coagulation and complement parameters, 3) hemolysis observed with the Sarns-3M pump in vitro was not evidenced in vivo, and 4) in vitro evidenced centrifugal pump differences may not be realized in vivo.

  5. Sobre la muerte voluntaria

    Directory of Open Access Journals (Sweden)

    Juan Álvarez-Cienfuegos Fidalgo

    2012-03-01

    Full Text Available El problema de cómo morir en nuestra sociedad se ha convertido en una inquietud para los ciudadanos y la reflexión moral. Especialmcnte por dos razones: por el desarrollo de la tecnología médica y por el hecho de que la mayor parte de los fallecimientos tienen lugar fuera del hogar, donde tradicionalmente ocurra el deceso. El presente artículo tiene como objetivo acercarse a esta cuestión. Para ello, se parte de la autonomía del ciudadano, con derecho a decidir sobre lo que considera cuál sea su manera de vivir y de morir. A tal fin, se hace una breve introducción sobre el dolor, el suicidio y la muerte, desde un punto de vista antropológico, pasando, después, a mostrar las cuestiones relacionadas con el problema de la eutanasia, donde la atención se dirigirá, ante todo, al enjuiciamiento crítico del tenso equilibrio en el que se mantienen dos principios fundamentales de la bioética: el de no maleficencia y el de autonomía del ciudadano.The problem of how to die in modern society has become a concern for both the citizen and moral reflection for two reasons in particular: due to developments in medical technology, and because most deaths occur outside the honre, where they traditionaÍlY took place. This paper addresses this issue, starting from citizen autonomy, the right to decide on what s/he considers to be his or her way of living and dying. To this end, a brief introduction considers pain, suicide and death from an anthropological viewpoint. Questions related to the problem of euthanasia are then exposed, with particular attention to, above all the critical judgement of the tense balance in which two fundamental principies of bioethics are held, the principle of non-maleficence and that of citizen autonomy.

  6. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    Energy Technology Data Exchange (ETDEWEB)

    Cai, X.Z. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Huang, W.Y.; Qiao, Y.; Chen, Y.; Du, S.Y.; Chen, D.; Yu, S. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Liu, N. [Department of Nephrology, First Affiliated Hospital, China Medical University, Shenyang (China); Dou, L.Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Jiang, Y. [Central Laboratory, First Affiliated Hospital, China Medical University, Shenyang (China); Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang (China); Department of Dermatology, First Affiliated Hospital, China Medical University, Shenyang (China)

    2014-10-17

    The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the expression of TIM-3 mRNA is associated with pathogenesis of SLE. Quantitative real-time reverse transcription-polymerase chain reaction analysis (qRT-PCR) was used to determine TIM-1, TIM-3, and TIM-4 mRNA expression in peripheral blood mononuclear cells (PBMCs) from 132 patients with SLE and 62 healthy controls. The PBMC surface protein expression of TIMs in PBMCs from 20 SLE patients and 15 healthy controls was assayed by flow cytometry. Only TIM-3 mRNA expression decreased significantly in SLE patients compared with healthy controls (P<0.001). No significant differences in TIM family protein expression were observed in leukocytes from SLE patients and healthy controls (P>0.05). SLE patients with lupus nephritis (LN) had a significantly lower expression of TIM-3 mRNA than those without LN (P=0.001). There was no significant difference in the expression of TIM-3 mRNA within different classes of LN (P>0.05). Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (r{sub s}=0.283, P=0.049) and serum albumin (r{sub s}=0.297, P=0.047). TIM-3 mRNA expression was weakly correlated with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; r{sub s}=-0.272, P=0.032). Our results suggest that below-normal expression of TIM-3 mRNA in PBMC may be involved in the pathogenesis of SLE.

  7. Downregulation of TIM-3 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    International Nuclear Information System (INIS)

    The T-cell immunoglobulin and mucin domain (TIM) family is associated with autoimmune diseases, but its expression level in the immune cells of systemic lupus erythematosus (SLE) patients is not known. The aim of this study was to investigate whether the expression of TIM-3 mRNA is associated with pathogenesis of SLE. Quantitative real-time reverse transcription-polymerase chain reaction analysis (qRT-PCR) was used to determine TIM-1, TIM-3, and TIM-4 mRNA expression in peripheral blood mononuclear cells (PBMCs) from 132 patients with SLE and 62 healthy controls. The PBMC surface protein expression of TIMs in PBMCs from 20 SLE patients and 15 healthy controls was assayed by flow cytometry. Only TIM-3 mRNA expression decreased significantly in SLE patients compared with healthy controls (P<0.001). No significant differences in TIM family protein expression were observed in leukocytes from SLE patients and healthy controls (P>0.05). SLE patients with lupus nephritis (LN) had a significantly lower expression of TIM-3 mRNA than those without LN (P=0.001). There was no significant difference in the expression of TIM-3 mRNA within different classes of LN (P>0.05). Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (rs=0.283, P=0.049) and serum albumin (rs=0.297, P=0.047). TIM-3 mRNA expression was weakly correlated with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; rs=-0.272, P=0.032). Our results suggest that below-normal expression of TIM-3 mRNA in PBMC may be involved in the pathogenesis of SLE

  8. Sobre el nombre "Quechua"

    Directory of Open Access Journals (Sweden)

    Rodolfo Cerrón-Palomino

    1985-06-01

    Full Text Available Uno de los primeros problemas con el que a menudo tropiezael estudioso de los idiomas ágrafos, como es el caso de las lenguasaborígenes de América, es el de su denominación (glotónimo.En la medida ,en que, por razones históricas, las noticias sobretales lenguas, y por consiguiente los primeros estudios sobre lasmismas, surgen a partir del contacto con los miembros de la civilización occidental, los nombres de los distintos idiomas, así comode los grupos étnicos que los manejan, son el resultado casi siempre arbitrario cie designaciones fortuitas hechas por viajeros, misiioneros y exploradores, quienes por lo general se basan, para ello, bien en descripciones físicas de los grupo étnicos, en ciertos indios geográficos que constituyen el habitat de los mismos, e incluso en prejuicios que se nutren de un marcado europocentrismo.

  9. Refletindo sobre idosos institucionalizado

    Directory of Open Access Journals (Sweden)

    Cenir Gonçalves Tier

    2004-06-01

    Full Text Available Trata-se de uma pesquisa qualitativa, descritiva que teve por objetivo identificar como vem sendo o relacionamento idoso-família, identificando os motivos que levaram os familiares a optarem pela institucionalização do seu idoso, obtendo-se também a visão da família sobre o cuidado no lar. Para coleta dos dados utilizou-se um instrumento com perguntas abertas. A coleta dos dados efetivou-se nos meses de agosto de 2002 a julho de 2003, sendo sujeitos da pesquisa, familiares de idosos de uma instituição asilar em um município da região noroeste do Rio Grande do Sul. Através da análise de conteúdo constatou-se que a maior dificuldade encontrada pela família, visando dispensar cuidados ao idoso é a "falta de tempo para cuidar" do seu familiar idoso, pois a maioria deles exige cuidados em tempo integral.

  10. An assessment of beaked redfish (S. mentella and S. fasciatus) in NAFO division 3M (with an approach to the likely impact of recent 3M cod growth on redfish natural mortality)

    OpenAIRE

    Ávila de Melo, A.; SABORIDO-REY Fran; González-Troncoso, Diana; Pochtar, Maria; Alpoim, R. (Ricardo)

    2011-01-01

    The 3M redfish assessment is focused on the beaked redfish, regarded as a management unit composed of two populations from two very similar species: the Flemish Cap S. mentella and S. fasciatus. The reason for this approach is the historical dominance of this group in the 3M redfish commercial catch until 2005. However a new golden redfish fishery (S. marinus) started on September 2005 on shallower depths of the Flemish Cap bank above 300m. This new reality implied a revision of c...

  11. CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes.

    Science.gov (United States)

    Wang, Miao-xing; Itoh, Masanori; Li, Shimo; Hida, Yoko; Ohta, Kazunori; Hayakawa, Miki; Nishida, Emika; Ueda, Masashi; Islam, Saiful; Tana; Nakagawa, Toshiyuki

    2016-01-29

    Cell death abnormal (ced)-3 and ced-4 genes regulate apoptosis to maintain tissue homeostasis in Caenorhabditis elegans. Apoptosome formation and CED-4 translocation drive CED-3 activation. However, the precise role of CED-4 translocation is not yet fully understood. In this study, using a combination of immunoprecipitation and reverse transcription-polymerase chain reaction methods in cells and a glutathione-S-transferase pull down assay in a cell-free system, we show that CED-4 binds ced-3 mRNA. In the presence of ced-3 mRNA, CED-4 protein is enriched in the microsomal fraction and interacts with ribosomal protein L10a in mammalian cells, increasing the levels of CED-3. These results suggest that CED-4 forms a complex with ced-3 mRNA and delivers it to ribosomes for translation.

  12. Study on New Typical Ionic Clusters K+(KNO3)n and NO3-(KNO3)m

    Institute of Scientific and Technical Information of China (English)

    石磊; 刘志强; 宋凤瑞; 刘淑莹

    2001-01-01

    The sample solution of KNO3 is ejectedinto the gas phase and the ionic clusters of K+(KNO3)n and NO3-(KNO3)m, are formed and observed by electrospray ionization mass spectrometry (ESIMS). The full mass spectra of both the positive ion and the negative ion show that the differences between each peak nearby are all about 101 ( m/ z ), which correspond to the molecular weight of KNO3. The general formula of the ionic clusters can be assigned as K+ (KNO3)n and NO3-(KNO3)m.

  13. Decrease of FOXP3 mRNA in CD4~+ T cells in latent autoimmune diabetes in adult

    Institute of Scientific and Technical Information of China (English)

    杨治芳

    2006-01-01

    Objective To study the percentage of peripheral blood CD4+ CD25+ T cells and the expression of F0XP3 mRNA in patients with latent autoimmune diabetes in adult (LADA). Methods Fresh peripheral blood samples were obtained from 60 patients with LADA,30 patients with type 2 diabetes and 30 age- and sex-matched

  14. On the multi-index (3m-parametric) Mittag-Leffler functions, fractional calculus relations and series convergence

    Science.gov (United States)

    Paneva-Konovska, Jordanka

    2013-10-01

    In this paper we consider a family of 3m-indices generalizations of the classical Mittag-Leffler function, called multi-index (3m-parametric) Mittag-Leffler functions. We survey the basic properties of these entire functions, find their order and type, and new representations by means of Mellin-Barnes type contour integrals, Wright pΨq-functions and Fox H-functions, asymptotic estimates. Formulas for integer and fractional order integration and differentiations are found, and these are extended also for the operators of the generalized fractional calculus (multiple Erdélyi-Kober operators). Some interesting particular cases of the multi-index Mittag-Leffler functions are discussed. The convergence of series of such type functions in the complex plane is considered, and analogues of the Cauchy-Hadamard, Abel, Tauber and Littlewood theorems are provided.

  15. Separation of isotope mixtures of molecular hydrogen on NaX-3M zeolite. 2. Isotopic equilibrium

    International Nuclear Information System (INIS)

    Isotopic equilibrium in the molecular hydrogen-NaX-3M zeolite system was investigated. Sorption isotherms of H2, D2, HD, HT, DT, T2 on zeolite were used to calculate the dependencies of binary factors of separation of isotope mixtures of molecular hydrogen on temperature (30-100 K) and pressure (0.25x105-1x107 Pa), which were compared with experimentally obtained results. Satisfactory agreement of experimental and calculation data was obtained

  16. Fermi level tuning in (Y1-yMy)1-xUxPd3 (M=Th, La)

    International Nuclear Information System (INIS)

    The effects of the increase of the U 5f binding energy and the decrease in the localized U 5f electron-conduction electron hybridization on the Kondo temperature, with U intersite interactions held constant to first approximation, are under investigation by means of electrical resistivity, magnetic susceptibility, and specific heat as a function of y for fixed values of x in the (Y1-yMy)1-xUxPd3 (M=Th, La) systems. ((orig.))

  17. Acueducto pretensado sobre el Holme

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1958-04-01

    Full Text Available Breve descripción del paso de una canalización de 0,60 m de diámetro, destinada al abastecimiento de aguas, sobre el río Holme (Inglaterra. El puente formado tiene dos vigas de hormigón pretensado, cuyas armaduras se componen de barras McCall.

  18. Room temperature syntheses and thermal behaviors of hydrogarnets Sr3M2(OH)12 (M = Al, Cr and Fe)

    International Nuclear Information System (INIS)

    Highlights: • All starting materials were common metal inorganic salts. • Hydrogarnets were synthesized by solid state reaction at room temperature. • The novel synthesis method has an advantage of quick reaction and easy operation. • As-synthesized hydrogarnets have different morphologies. - Abstract: Hydrogarnets Sr3M2(OH)12 (M = Al, Cr and Fe) were synthesized through a solid state reaction at room temperature with Al(NO3)3·9H2O, CrCl3·6H2O, FeCl3·6H2O, Sr(NO3)2 and NaOH as the starting materials. All X-ray diffraction (XRD) data of Sr3M2(OH)12 were indexed by the cubic system with the space group of Ia−3d. XRD, differential thermal analysis and thermogravimetric (DTA–TG), and scanning electron microscopy (SEM) were employed to investigate the structural stability, thermal properties and morphologies of Sr based hydrogarnets. The cause of room temperature synthesis and the thermal decomposition behaviors of Sr-based hydrogarnets Sr3M2(OH)12 (M = Al, Cr and Fe) are discussed

  19. Design of multichord Hα detector arrays for the U-3M torsatron and identification of rotating plasma perturbations

    Science.gov (United States)

    Dreval, M. B.; Shapoval, A. M.; Ozherelyev, F. I.; Makhov, M. M.

    2016-07-01

    An Hα camera has been designed and installed in the U-3M torsatron for spatially and temporally resolved measurements. This device provides fast measurements of the emission brightness profile in the noisy environment of the radio frequency (RF) heated plasma. Unusual topology of diagnostics and the data acquisition system are applied. All the system components, including digitizers, are assembled in a single unit. It allows the suppression of a low-frequency electromagnetic interference by eliminating the ground loops. And the suppression of RF noises is achieved by eliminating the signal interface cables and digital interface cables in the design. The Wi-Fi interface is used to prevent a ground loop in the data transfer stage. The achieved sensitivity of our diagnostics is high enough for measuring the Hα emission from the low-density (ne ≈ (1-2)ṡ1010 cm-3) plasma with a temporal resolution of about 20 μs in the noisy environment. Different types of Hα emission fluctuations within the frequency range of 1-5 kHz and poloidal mode numbers m = 0 and m = 5 have been observed in U-3M. A simple technique of the line-of-sight data analysis, based on the U-3M magnetic surface asymmetry, is proposed and used for the spatial localization of the rotating mode and for the determination of mode numbers and its poloidal rotation direction using a single Hα array.

  20. Third molar maturity index (I3M) for assessing age of majority in a black African population in Botswana.

    Science.gov (United States)

    Cavrić, Jelena; Galić, Ivan; Vodanović, Marin; Brkić, Hrvoje; Gregov, Jelena; Viva, Serena; Rey, Laura; Cameriere, Roberto

    2016-07-01

    Assessment of legal age, also known as age of majority, is a controversial issue as there are few body biomarkers or evidence during late adolescence differentiating a subject from being a minor or adult. The third molar was recognized as a suitable site for age examination in late adolescence. We analyzed the development of the left mandibular third molar by the third molar maturity index (I3M) and a specific cut-off value of I3M = 0.08, established by Cameriere et al. in 2008 and used it for discriminating between minors and adult black Africans from Gaborone, Botswana. A final sample of panoramic radiographs (OPTs) of 1294 people (582 males and 712 females) aged between 13 and 23 years was evaluated. The real age decreased as I3M gradually increased. There was no statistically significant difference in the third molar development evaluated using I3M between males and females (p > 0.05) across different I3M classes. Results of 2 × 2 contingency tables for different cut-off values indicated that I3M = 0.08 was useful in discriminating between adults and minors. Precisely, for I3M = 0.08, the values of accuracy or overall fraction of correctly classified were 0.91 in males with a 95 % confidence interval (95 % CI) of 0.88 to 0.93 and 0.92 (95 % CI, 0.90 to 0.93) in females. Values of sensitivity of the test or the proportion of participants being 18 years and older were 0.88 (95 % CI, 0.87 to 0.90) in males and 0.88 (95 % CI, 0.90 to 0.93) in females, while values of specificity or proportion of individuals younger than 18 who have I3M age of 18 years in Botswana. Further studies should address the usefulness of this method and specific cut-off for different adolescent populations.

  1. SF3M 2.0: improvement of 3D photo-reconstruction interface based on freely available software

    Science.gov (United States)

    Castillo, Carlos; James, Michael R.; Pérez, Rafael; Gómez, Jose A.

    2016-04-01

    During recent years, a number of tools based on Structure-from-Motion algorithms have been released for full image-based 3D reconstruction either freely (e.g. Bundler, PMVS2, VisualSFM, MicMac) or commercially (e.g. Agisoft PhotoScan). The SF3M interface was developed in Matlab® to use link software developments (VisualSFM, CloudCompare) and new applications to create a semi-automated workflow including reconstruction, georeferencing and point-cloud filtering, and has been tested for gully erosion assessment with terrestrial images (Castillo et al., 2015). The main aim of this work to provide an improved freely-available and easy-to-use alternative for 3D reconstruction intended for public agencies, non-profit organisations, researchers and other stakeholders interested in 3D modelling. In this communication we present SF3M 2.0, a new version of the graphical user interface. In this case, the SfM module is based on MicMac, an open-software tool (Pierrot-Deseilligny and Cléry, 2011) which provides advanced features such as camera calibration and constrained bundle adjustment using ground control points. SF3M 2.0 will be tested in two scenarios: a) using the same ground-based image set tested in Castillo et al. (2015) to compare the performance of both versions and b) using aerial images taken from a helium balloon to assess a gully network in a 40-hectares catchment. In this study we explore the advantages of SF3M 2.0, explain its operation and evaluate its accuracy and performance. This tool will be also available for free download. References Castillo, C., James, M.R., Redel-Macías, M. D., Pérez, R., and Gómez, J.A.: SF3M software: 3-D photo-reconstruction for non-expert users and its application to a gully network, SOIL, 1, 583-594. Pierrot-Deseilligny, M and Cléry, I. APERO, an Open Source Bundle Adjusment Software for Automatic Calibration and Orientation of a Set of Images. Proceedings of the ISPRS Commission V Symposium, Image Engineering and Vision

  2. Clinical significance of expression of Foxp3 mRNA in patients with asthma%哮喘患者外周血转录因子Foxp3mRNA表达水平及临床意义

    Institute of Scientific and Technical Information of China (English)

    谭楠

    2012-01-01

    目的:探讨哮喘患者外周血叉头翼状螺旋转录因子3(Foxp3)mRNA表达水平及临床意义.方法:采用实时荧光定量PCR技术检测63例哮喘患者和40例正常对照组外周血中转录因子Foxp3 mRNA表达水平.结果:哮喘组患者外周血Foxp3 mRNA表达水平(0.32±0.13)较对照组(1.15±0.31)明显降低,差异有统计学意义(P<0.05);急性发作期患者外周血Foxp3 mRNA表达水平(0.22±0.06)较非急性发作期患者(0.47±0.15)明显降低,差异有统计学意义(P<0.05);急性发作期重度患者外周血Foxp3 mRNA表达水平(0.18±0.04)较对照组(0.29±0.07)明显降低,差异有统计学意义(P<0.05).结论:哮喘患者外周血中转录因子Foxp3 mRNA表达水平明显降低且与疾病分期及病情严重程度密切相关,Foxp3可能参与了哮喘发病过程.%Objective:To explore the expression of Foxp3 Mrna in peripheral blood from patients with asthma and its clinical significance. Methods: 63 patients with asthma and 40 controls were enrolled. The expressions of Foxp3 Mrna were analyzed by real-time PCR. Results:The Mrna levels of Foxp3 in peripheral blood from patients with asthma (0. 32 ± 0. 13) were significantly decreased. There were significantly different between the experimental group and control group (1. 15 ± 0. 31) (P <0. 05). The Mrna levels of Foxp3 in in peripheral blood from patients during acute phase (. 22 ± 0. 06) were in patients during chronic phase (0. 47+0. 15). The Mrna levels of Foxp3 in severe group (0. 18 ± 0. 04) were significantly decreased. There were significantly different between the severe group and slight, moderate group (0. 29 ± 0. 07) (P <0. 05). Conclusion:The Mrna levels of Foxp3 in peripheral blood from patients with asthma are significantly decreased and have association with disease stages and disease severity. Foxp3 may participate in the development of asthma.

  3. Bolt study - behaviour of bolts in drop accident scenarios of the Nirex 3m{sup 3} Box ILW package

    Energy Technology Data Exchange (ETDEWEB)

    Turner, G. [United Kingdom Nirex Ltd., Harwell (United Kingdom); Tso, C.F. [Arup, London (United Kingdom)

    2004-07-01

    The mission of Nirex is to provide the UK with safe, environmentally sound and publicly acceptable options for the long-term management of radioactive materials. One of the key tasks is to ensure that waste is packaged by waste producers in a form which is suitable for safe storage, transport, handling and potential disposal. In pursuit of this key requirement, Nirex has developed specifications to set the standard for the design and performance of waste packages, and has developed standard containers for the packaging of intermediate level (ILW) and some low level waste (LLW) - one of these is the 3m{sup 3} Box for immobilised operational and decommissioning ILW. The dimension envelope of this package is 1716 mm x 1716 mm in plan with 430 mm corner radii, 1226 mm tall. The maximum loaded weight is 12 tonnes. A generic design of this container has been developed, which is a welded structure manufactured from austenitic stainless steel (EN 10088-2 steel number 1.4404). The lid is connected to the body by 28 stainless steel bolts. An extensive study was carried out to develop a robust FE model of the bolts. The specific focus of this work was to use improved bolt modelling to optimize the design of the 3m{sup 3} Box, although this work could be applied to other bolted containers. This paper presents a summary of the findings from the study as follows: 1. Development of a FE bolt model for application in a 3m{sup 3} Box model. 2. Development and execution of a bolt testing programme which included tensile and shear tests on a total of 88 bolts, representing four grades of stainless steel materials, three thread sizes, and two geometries at three strain rates. 3. Benchmarking of the FE bolt model that can be used with confidence in simulating waste package behaviour in drop scenarios.

  4. Breve informe sobre la coca

    Directory of Open Access Journals (Sweden)

    Lauro Hinostroza García

    1985-12-01

    Full Text Available El presente informe se integra en la investigación dirigida por el doctor Juan Ossio, por encargo de la Organización de los Estados Americanos (O.E.A. sobre “EFECTOS SOCIALES, CULTURALES, MÉDICOS Y ECONÓMICOS DEL USO TRADICIONAL DE LA COCA EN POBLACIONES DEL ANTIPLANO Y SIERRA DEL PERÚ, EN ESPECIAL DE LAS POBLACIONES INDÍGENAS”. Expone tópicos sobre la hoja de coca en la cultura andina: criterios clasificatorios, mitos, canciones y una muestra de qatipay o seguimiento. Este último es una práctica ritual importante para el campesinado andino, orienta el presente, pasado y futuro de toda su actividad. Cada hoja, por su forma, posición y tamaño, develará los roles sociales que ha de asumir, es decir los misterios del tiempo.

  5. Extension of Studies with 3M Empore TM and Selentec MAG *SEP SM Technologies for Improved Radionuclide Field Sampling

    International Nuclear Information System (INIS)

    The Savannah River Technology Center is evaluating new field sampling methodologies to more easily determine concentrations of radionuclides in aqueous systems. One methodology studied makes use of 3M EmporeTM disks. The disks are composed of selective resins embedded in a Teflon support. The disks remove the ion of interest from aqueous solutions when the solution is passed through the disk. The disk can then be counted directly to quantify the isotope of interest. Four types of disks were studied during this work: for the extraction of technetium (two types), cesium, plutonium, and strontium. A sampler has been developed for automated, unattended, in situ use of the EmporeTM disks

  6. MRI of the lung using hyperpolarized He-3 at very low magnetic field (3 mT)

    CERN Document Server

    Bidinosti, C P; Tastevin, G; Vignaud, A; Nacher, P J

    2004-01-01

    Optical pumping of He-3 produces large (hyper) nuclear-spin polarizations independent of the magnetic resonance imaging (MRI) field strength. This allows lung MRI to be performed at reduced fields with many associated benefits, such as lower tissue susceptibility gradients and decreased power absorption rates. Here we present results of 2D imaging as well as accurate 1D gas diffusion mapping of the human lung using He-3 at very low field (3 mT). Furthermore, measurements of transverse relaxation in zero applied gradient are shown to accurately track pulmonary oxygen partial pressure, opening the way for novel imaging sequences.

  7. Synthesis of titanates MTiO{sub 3} (M = Mn, Co, Ni) by the sol-gel method

    Energy Technology Data Exchange (ETDEWEB)

    Moreno, J.; Tavizon, G.; Vicente, L. [UNAM, Mexico City (Mexico). Dept. de Fisica y Quimica Teorica; Viveros, T. [UAM-Iztapalapa, Mexico City (Mexico). Dept. de Ingenieria Quimica

    1996-12-31

    The titanates MTiO{sub 3} (M = Ni, Co, Mn) were prepared by a sol-gel method. The reaction between the metal solution and titanium butoxide leads to the formation of gels. The amorphous gels so obtained under different pH conditions, were calcined at temperatures between 750 C and 1,200 C to obtain in some cases high purity, crystalline MTiO{sub 3} powders. The characterization of the samples was done by X-ray powder diffraction, differential thermal analysis (DTA), thermal gravimetry (TG) and BET surface measurements.

  8. FABRICATION OF A 3 m Ø x 5 m SUPERCONDUCTING SOLENOID FOR THE FERMILAB COLLIDER DETECTOR FACILITY

    OpenAIRE

    Minemura, H.; Mori, S.; Yoshizaki, R.; Kondo, K.(Yamagata University, Yamagata, 992-8510, Japan); Fast, R; Kephart, R.; Wands, R.; Yamada, R.

    1984-01-01

    The 3mØ x 5m (1.5 Tesla) superconducting solenoid for the Fermilab Collider Detector Facility (CDF) is under construction in Japan. The coil consists of a single layer aluminum-stabilized monolithic NbTi/Cu superconductor fabricated with the EFT (extrusion with front tension) method. The forced flow cooling method of two-phase helium is used. In order to minimize the material thickness of the solenoid the coil is built without a permanent inner bobbin. The radial electromagnetic forces are su...

  9. Mutual transformation of light waves by reflection holograms in photorefractive crystals of the 4-bar 3m symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Naunyka, V. N.; Shepelevich, V. V., E-mail: vasshep@inbox.ru [Mozyr State Pedagogical University (Belarus)

    2011-05-15

    The mutual transformation of light waves in the case of their simultaneous diffraction from a bulk reflection phase hologram, which was formed in a cubic photorefractive crystal of the 4-bar 3m symmetry class, has been studied. The indicator surfaces of the polarization-optimized values of the relative intensity of the object wave, which make it possible to determine the amplification of this wave for any crystal cut, are constructed. The linear polarization azimuths at which the energy exchange between the light waves reaches a maximum are found numerically for crystals of different cuts.

  10. Sobre la verdad en periodismo

    Directory of Open Access Journals (Sweden)

    Julio Estremadoyro Alegre

    2011-05-01

    Full Text Available Cuando un periodista informa sobre un desastre natural, con granpérdida de vidas, las autoridades y las fuentes de primera manodan cifras que son difundidas como verdades del suceso. Sinembargo, y la experiencia lo confirma, al día siguiente la cifraspueden haber cambiado y, por lo tanto, la verdad informativa esotra. Y así, sucesivamente, cada día habrá novedades y nuevas cifras verdaderas.

  11. SNaPshot技术检测Y-SNP位点O3-M122单倍群的应用%The application of Y-SNP genotyping by SNaPshot assay under the O3-M122 haplogroup

    Institute of Scientific and Technical Information of China (English)

    孙亚男; 李安; 史斌; 董庆旭; 李貌; 何玮; 翟滇; 程宝文

    2013-01-01

    目的 采用SNaPshot技术检测案例检材O3-M122位点6个亚群的分型,并调查其在云南3个民族无关男性人群中的频率分布.方法 建立5-plex Y-SNPs复合扩增体系,采用SNaPshot Multiplex试剂盒,检测案例检材O3-M122单倍群下O3*-M122、O3a*-M324、O3a3*-P201、O3a3b*-M7、O3a3c*-M134、O3a3c1*-M117共6个Y-SNPs分型,并对上述6个Y-SNPs在云南佤族、白族、傣族共174名无关男性个体中的分布进行调查.结果 17份案例检材均得到良好的分型结果.上述3个民族分别在3个、5个、5个位点上发现多态性,其中佤族O3a3*-P201分布频率最高(0.430 0);白族O3a*-M324频率最高(0.2123);傣族O3a3c1*-M117频率最高(0.158 2).结论 多重PCR反应及SNaPshot技术的联合应用适用于法医案件检材DNA检测,3个民族多态性数据可为相关应用所参考.

  12. STUDY OF MORPHOLOGICAL CHANGES OF HEART IN VIRAL MYOCARDITIS CAUSED BY REPETITIVE INFECTION OF CVB3m

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Objective To investigate the morphological changes of heart in viral myocarditis caused by repetitive infection of CVB3m. Methods 4-week-old mice were infected four times intraperitoneally with a timedependent dose and killed at the 10th,30th and 60th day after the final infection respectively, then we examined the heart changes and collagen hyperplasia by HE, VG stain and IHC. Results Heart damage appeared very serious at the tenth day, even there were small necrotic foci at the day of 30th, but we could not see any injury of heart 2 months later after final infection. Collagen turned up at the tenth day and there was much more collagen in heart and increased PCVA, CVF index at the sixtieth day. The IHC of collagen demonstrated the collagen Ⅰ hyperplasia was much obvious compared to collagen Ⅲ. Conclusion It strongly indicated that repetitive infection of CVB3m could lead to heart fibrosis and ventricular remodeling, which resulted in decreased systolic and diastolic function of heart.

  13. PARTICIPAÇÃO DO CONSUMIDOR NO DESENVOLVIMENTO DO SISTEMA LINUX: APLICAÇÃO DO 3M DE MOWEN

    Directory of Open Access Journals (Sweden)

    Alexandre Eugenio Pieske

    2012-03-01

    Full Text Available Este trabalho investiga o prosumidor, indivíduo parte produtor, parte consumidor. Para entender seu comportamento, selecionou-se o 3M (Modelo Metateórico de Motivação e Personalidade, de Mowen (2000, adaptado por Monteiro (2006, que interpreta o comportamento do consumidor por traços de personalidade. O objeto de estudo são prosumidores do Linux, já que este sistema operacional possibilita livre modifi cação. Foi realizada pesquisa em duas etapas: qualitativa preparatória e quantitativa, para testar a aplicação do modelo. Foram realizadas entrevistas individuais com usuários Linux, resultando na identifi cação de cinco níveis de participação. Na segunda fase, foi aplicado um survey, pela Internet, a membros de comunidades Linux. Por meio de modelagem em equações estruturais, o 3M foi aplicado, fazendo-se os devidos ajustes. Apesar de os coefi cientes de determinação terem sido signifi cativos, alguns índices de ajuste apresentaram-se baixos.

  14. Photoelectron velocity-map imaging and theoretical studies of heteronuclear metal carbonyls MNi(CO)3- (M = Mg, Ca, Al)

    Science.gov (United States)

    Xie, Hua; Zou, Jinghan; Yuan, Qinqin; Fan, Hongjun; Tang, Zichao; Jiang, Ling

    2016-03-01

    The heteronuclear metal carbonyl anions MNi(CO)3- (M = Mg, Ca, Al) have been investigated using photoelectron velocity-map imaging spectroscopy. Electron affinities of neutral MNi(CO)3 (M = Mg, Ca, Al) are measured from the photoelectron spectra to be 1.064 ± 0.063, 1.050 ± 0.064, and 1.541 ± 0.040 eV, respectively. The C-O stretching mode in these three clusters is observed and the vibrational frequency is determined to be 2049, 2000, and 2041 cm-1 for MgNi(CO)3, CaNi(CO)3, and AlNi(CO)3, respectively. Density functional theory calculations are carried out to elucidate the geometric and electronic structures and to aid the experimental assignments. It has been found that three terminal carbonyls are preferentially bonded to the nickel atom in these heterobinuclear nickel carbonyls MNi(CO)3-1/0, resulting in the formation of the Ni(CO)3 motif. Ni remains the 18-electron configuration for MgNi(CO)3 and CaNi(CO)3 neutrals, but not for AlNi(CO)3. This is different from the homobinuclear nickel carbonyl Ni-Ni(CO)3 with the involvement of three bridging ligands. Present findings would be helpful for understanding CO adsorption on alloy surfaces.

  15. Measurements of radiation exposure on commercial aircraft with the LIULIN-3M instrument; Mesure de l'exposition aux radiations sur les vols commerciaux avec l'equipement LIULIN-3M

    Energy Technology Data Exchange (ETDEWEB)

    Stassinopoulos, E.G. [NASA Centre des Vols Spatiaux Goddard, Greenbelt, MD (United States); Stauffer, C.A. [Stinger Gaffarian Technologies, Greenbelt, MD (United States); Dachev, T.P.; Tomov, B.T.; Dimitrov, P.G. [Academie des Sciences, Bulgarie, Lab. d' Etudes des Influences Soleil-Terre, Sofia (Bulgaria); Brucker, G.J. [Radiation Effects Consultants, Inc., West Long Branch, NJ (United States)

    1999-07-01

    The LIULIN-3M evolved from an international cooperative project by a group of Bulgarian, Russian, German, and American scientists. The radiometer is a low power, small size, light weight, and low cost instrument composed of a solid state detector (SSD) with supporting electronics that enable it to operate as a pulse height analyzer of energy deposited in the detector, and to obtain from these measurements the total dose or the dose rate produced by charged particles. The instrument has also been used as a low-LET radiation spectrometer for measuring biological doses of potential human exposures. A flash memory allows self-storage of data during flights and post flight retrieval. Results will be presented and discussed. (author)

  16. Phycocyanin for protecting brain ischemia-reperfusion injury and its effect on the expression of Caspase-3 mRNA

    Institute of Scientific and Technical Information of China (English)

    Xuewei Yang; Yunliang Guo; Hongbing Chen

    2006-01-01

    BACKGROUND: Phycocyanin can anti-oxidize and clear free radial. Whether its protective effect on brain is related to Caspase-3, the promoter and operator of apoptosis, is highly concerned.OBJECTIVE: To observe phycocyanin for protecting nerve function and reducing the size of cerebral infarction of rats with brain ischemia-reperfusion and its effect on the expression of Caspase-3 mRNA.DESIGN: A randomized controlled experiment.SETrING: Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University.MATERIALS: Totally 84 adult healthy female Wistar rats, weighing 210 to 250 g, of clean grade, were provided by the Animal Experimental Center of Shandong University. Phycocyanin (Institute of Oceanography of Chinese Academy of Sciences) was used.METHODS: This experiment was carried out in the Key Laboratory for Prevention and Treatment of Brain Diseases during May to December 2005. ① The rats were randomized into sham-operation group (n=4),control group (n=40) and phycocyanin-treated group (n=40). Middle cerebral artery occlusion/reperfusion (MACO/R) models were created on the rats of control and phycocyanin-treated groups with suture-occluded method by inserting a thread into left side external-internal carotid artery. In the sham-operation group, inserting suture was omitted. After ischemia for 1 hour and reperfusion for 2 hours, suspension of phycocyanin was intragastrically administrated into the rats of the phycocyanin-treated group at 100 mg/kg , and the same volume of normal saline was isochronously administrated into the rats of control group as the same. ② Six rats were chosen respectively from the control group and phycocyanin-treated group, then neurologic impairment degrees of rats were evaluated according to Bederson's grading. ③ Six rats were chosen respectively from the control and phycocyanin-treated groups. The isolated brain tissue was stained with triphenyltetrazolium chloride, and then the size of cerebral

  17. Nonlinear elastic properties of superconducting antiperovskites MNNi 3 (M =Zn, Cd, Mg, Al, Ga, and In) from first principles

    KAUST Repository

    Liu, Lili

    2014-05-22

    We present theoretical studies for the third-order elastic constants (TOECs) of superconducting antiperovskites MNNi 3 (M = Zn, Cd, Mg, Al, Ga, and In) using the density functional theory (DFT) and homogeneous deformation method. From the nonlinear least-square fitting, the elastic constants are extracted from a polynomial fit to the calculated strain-energy data. Calculated second-order elastic constants (SOECs) are compared with the previous theoretical calculations, and a very good agreement was found. The nonlinear effects often play an important role when the finite strains are larger than approximately 2.5 %. Besides, we have computed the pressure derivatives of SOECs and provided rough estimations for the Grüneisen constants of long-wavelength acoustic modes by using the calculated TOECs. © 2014 Springer Science+Business Media New York.

  18. Characteristics of the three-half-turn-antenna-driven RF discharge in the Uragan-3M torsatron

    Energy Technology Data Exchange (ETDEWEB)

    Grigor’eva, L. I.; Chechkin, V. V., E-mail: chechkin@ipp.kharkov.ua; Moiseenko, V. E.; Grekov, D. L.; Pavlichenko, R. O.; Lozin, A. V.; Tarasov, I. K.; Kulaga, A. Ye.; Zamanov, N. V.; Tretiak, K. K.; Kozulya, M. M.; Beletskii, A. A.; Kasilov, A. A.; Mironov, Yu. K.; Romanov, V. S.; Voitsenya, V. S. [National Science Center Kharkiv Institute of Physics and Technology, Institute of Plasma Physics (Ukraine)

    2015-12-15

    In the ℓ = 3 Uragan-3M torsatron hydrogen plasma is produced by RF fields in the Alfvén range of frequencies (ω ≤ ω{sub ci}). The initial (target) plasma with the line-averaged density of units 10{sup 12} cm{sup −3} is produced by a frame antenna with a broad spectrum of generated parallel wavenumbers. After this, to heat the plasma and bring its density to ∼10{sup 13} cm{sup –3}, another, shorter wavelength three-half-turn antenna with large transverse currents is used. The behavior of the density, electron temperature, and loss of the plasma supported by the three-half-turn antenna is studied depending on the RF power fed to the antenna and initial values of the density and electron temperature supplied by the frame antenna.

  19. Dry rehydratable film method for rapid enumeration of coliforms in foods (3M Petrifilm Rapid Coliform Count plate): collaborative study.

    Science.gov (United States)

    Kinneberg, Karen M; Lindberg, Kathryn G

    2002-01-01

    A rehydratable dry-film plating method for coliforms in foods, the 3M Petrifilm Rapid Coliform Count plate method, was compared with the U.S. Food and Drug Administration's Bacteriological Analytical Manual method for nondairy foods and the American Public Health Association's Standard Methods for the Examination of Dairy Products (SMEDP) method for dairy foods. Six food types, vanilla ice cream, cheddar cheese, fresh refrigerated uncooked pasta, wheat flour, prepared frozen macaroni and cheese, and frozen hash browns, were analyzed for coliforms by 11 collaborating laboratories. For each food product tested, the collaborators received 8 blind samples consisting of a control sample and 3 levels of inoculated sample, each in duplicate. The mean log counts for the methods were comparable. The repeatability and reproducibility variances of the Petrifilm Rapid Coliform Count method at 14 and 24 h were not significantly different from those of the standard methods.

  20. 3M Petrifilm Staph Express Count plate method for the enumeration of Staphylococcus aureus in selected dairy foods: collaborative study.

    Science.gov (United States)

    Silbernagel, Karen M; Jechorek, Robert P; Carver, Charles N; Horter, Barbara L; Lindberg, Kathryn G

    2003-01-01

    The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Five foods--ice cream, raw milk, yogurt, whey powder, and cheese--were analyzed for S. aureus by 12 collaborating laboratories. For each food tested, the collaborators received 8 blind test samples consisting of a control sample, a low inoculation level, a medium inoculation level, and a medium inoculation level with background flora, each in duplicate. The mean log10 counts for the methods were comparable for all 5 foods. The repeatability and reproducibility variances of the 24 h Petrifilm Staph Express Count plate method were similar to those of the 72 h standard method.

  1. Trends in (LaMnO3)n/(SrTiO3)m superlattices with varying layer thicknesses

    KAUST Repository

    Jilili, J.

    2015-09-01

    We investigate the thickness dependence of the structural, electronic, and magnetic properties of (LaMnO3)n/(SrTiO3)m (n, m = 2, 4, 6, 8) superlattices using density functional theory. The electronic structure turns out to be highly sensitive to the onsite Coulomb interaction. In contrast to bulk SrTiO3, strongly distorted O octahedra are observed in the SrTiO3 layers with a systematic off centering of the Ti atoms. The systems favour ferromagnetic spin ordering rather than the antiferromagnetic spin ordering of bulk LaMnO3 and all show half-metallicity, while a systematic reduction of the minority spin band gaps as a function of the LaMnO3 and SrTiO3 layer thicknesses originates from modifications of the Ti dxy states.

  2. Automated IBM PC/XT/AT based measurement and control system for the DRON-3M X-ray diffractometer

    International Nuclear Information System (INIS)

    An automated IBM PC/XT/AT based measurement and control system for the DRON-3M X-ray diffractometer is decribed. The system permits carrying out of real time diffractometer control automatic X-spectra measurement and data acquisition, as well as experimental information computing and representation. The electronic of the system consists of a CAMAC crate with analog and power modules, and a control and measurement organization module, performed as a single bord in the standard of PC electronics. The system provides X-spectra acquisition with volume up to 4K in the angle range from 100 to 160 degrees with a resolution of 0.01 degree, a dead time less than 1mks and an exposition time from tenths of a second to dozens of minutes. 3 refs.; 5 figs

  3. Piezoelectric Enhancement of (PbTiO3)m/(BaTiO3)n Ferroelectric Superlattices through Domain Engineering

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Liang; Wu, Pingping; Li, Yulan; Gopalan, Venkatraman; Eom, C.B.; Schlom, Darrell G.; Chen, Long-Qing

    2014-11-20

    The phase diagram of (PbTiO3)m/(BaTiO3)n ferroelectric superlattices was computed using the phase-field approach as a function of layer volume fraction and biaxial strain to tune ferroelectric properties through domain engineering. Two interesting domain structures are found: one with mixed Bloch-Néel-Ising domain wall structures and the other with stabilized monoclinic phases. The polarization of the monoclinic phase is able to rotate from out-of-plane to in-plane or vice versa under an electric field, and thus facilitates the domain reversal of rhombohedral domains. This contributes significantly to both reduced coercive fields and enhanced piezoelectric responses.

  4. Evaluation of the 3M Petrifilm Enterobacteriaceae Count plate method for the enumeration of Enterobacteriaceae in foods.

    Science.gov (United States)

    Silbernagel, Karen M; Lindberg, Kathryn G

    2002-09-01

    Results of the 3M Petrifilm Enterobacteriaceae Count (EB) plate method were compared with those of the standard violet red bile glucose agar (VRBG) method for the detection and enumeration of Enterobacteriaceae. Studies involving 107 bacterial strains demonstrated that the Petrifilm EB plate method is as sensitive as and more selective than the VRBG method. Sixty of the 62 pure Enterobacteriaceae cultures were recovered by both methods. In addition, 38 of the 45 non-Enterobacteriaceae organisms did not grow on the Petrifilm EB plate, while 28 of the 45 non-Enterobacteriaceae organisms did not grow on the VRBG plate. Colony counts from 174 naturally contaminated and 120 artificially inoculated dairy and nondairy food samples showed that the Petrifilm EB plate method performed as well as or better than the standard VRBG method for the enumeration of Enterobacteriaceae.

  5. Overview of the O3M SAF GOME-2 operational atmospheric composition and UV radiation data products and data availability

    Science.gov (United States)

    Hassinen, S.; Balis, D.; Bauer, H.; Begoin, M.; Delcloo, A.; Eleftheratos, K.; Gimeno Garcia, S.; Granville, J.; Grossi, M.; Hao, N.; Hedelt, P.; Hendrick, F.; Hess, M.; Heue, K.-P.; Hovila, J.; Jønch-Sørensen, H.; Kalakoski, N.; Kauppi, A.; Kiemle, S.; Kins, L.; Koukouli, M. E.; Kujanpää, J.; Lambert, J.-C.; Lang, R.; Lerot, C.; Loyola, D.; Pedergnana, M.; Pinardi, G.; Romahn, F.; van Roozendael, M.; Lutz, R.; De Smedt, I.; Stammes, P.; Steinbrecht, W.; Tamminen, J.; Theys, N.; Tilstra, L. G.; Tuinder, O. N. E.; Valks, P.; Zerefos, C.; Zimmer, W.; Zyrichidou, I.

    2016-02-01

    The three Global Ozone Monitoring Experiment-2 instruments will provide unique and long data sets for atmospheric research and applications. The complete time period will be 2007-2022, including the period of ozone depletion as well as the beginning of ozone layer recovery. Besides ozone chemistry, the GOME-2 (Global Ozone Monitoring Experiment-2) products are important e.g. for air quality studies, climate modelling, policy monitoring and hazard warnings. The heritage for GOME-2 is in the ERS/GOME and Envisat/SCIAMACHY instruments. The current Level 2 (L2) data cover a wide range of products such as ozone and minor trace gas columns (NO2, BrO, HCHO, H2O, SO2), vertical ozone profiles in high and low spatial resolution, absorbing aerosol indices, surface Lambertian-equivalent reflectivity database, clear-sky and cloud-corrected UV indices and surface UV fields with different weightings and photolysis rates. The Satellite Application Facility on Ozone and Atmospheric Chemistry Monitoring (O3M SAF) processes and disseminates data 24/7. Data quality is guaranteed by the detailed review processes for the algorithms, validation of the products as well as by a continuous quality monitoring of the products and processing. This paper provides an overview of the O3M SAF project background, current status and future plans for the utilisation of the GOME-2 data. An important focus is the provision of summaries of the GOME-2 products including product principles and validation examples together with sample images. Furthermore, this paper collects references to the detailed product algorithm and validation papers.

  6. Overview of the O3M SAF GOME-2 operational atmospheric composition and UV radiation data products and data availability

    Directory of Open Access Journals (Sweden)

    S. Hassinen

    2015-07-01

    Full Text Available The three GOME-2 instruments will provide unique and long data sets for atmospheric research and applications. The complete time period will be 2007–2022, including the period of ozone depletion as well as the beginning of ozone layer recovery. Besides ozone chemistry, the GOME-2 products are important e.g. for air quality studies, climate modeling, policy monitoring and hazard warnings. The heritage for GOME-2 is in the ERS/GOME and Envisat/SCIAMACHY instruments. The current Level 2 (L2 data cover a wide range of products such as trace gas columns (NO2, BrO, H2CO, H2O, SO2, tropospheric columns of NO2, total ozone columns and vertical ozone profiles in high and low spatial resolution, absorbing aerosol indices from the main science channels as well as from the polarization channels (AAI, AAI-PMD, Lambertian-equivalent reflectivity database, clear-sky and cloud-corrected UV indices and surface UV fields with different weightings and photolysis rates. The Ozone Monitoring and Atmospheric Composition Satellite Application Facility (O3M SAF processing and data dissemination is operational and running 24/7. Data quality is quarantined by the detailed review processes for the algorithms, validation of the products as well as by a continuous quality monitoring of the products and processing. This is an overview paper providing the O3M SAF project background, current status and future plans to utilization of the GOME-2 data. An important focus is the provision of summaries of the GOME-2 products including product principles and validation examples together with the product sample images. Furthermore, this paper collects the references to the detailed product algorithm and validation papers.

  7. Nota sobre Keynes y Brentano

    OpenAIRE

    Crespo, Ricardo F.; IAE (Universidad Austral) y CONICET

    2013-01-01

    Este trabajo explora la posibilidad de una relación entre el pensamiento de John Maynard Keynes y el del filósofo alemán Franz Brentano (1839-1917) en los campos lógico y epistemológico. George E. Moore -profesor de Keynes- y Keynes mismo leyeron y alabaron el libro de Brentano El origen del conocimiento moral (1889). ¿Tomó Keynes algunas ideas lógicas o epistemológicas de Brentano? El trabajo sugiere que, a pesar de ciertas similitudes entre las ideas lógicas y sobre la verdad de Keynes y Br...

  8. Thomas Hobbes: sobre el miedo

    OpenAIRE

    Carlos Bührle

    2004-01-01

    Este trabajo pretende echar cierta luz sobre el papel del miedo en el pensamiento político de Hobbes. Sabido es que esta pasión subyace al contrato social, en el sentido de que impulsa al hombre a abandonar el estado de naturaleza a fin de encontrar seguridad y de deshacerse de la amenaza de la muerte violenta. Teniendo en cuenta que el miedo y la muerte son inseparables en la filosofía de Hobbes, surge una pregunta fundamental: ¿hasta qué punto podemos decir que el miedo desaparece completam...

  9. Modelos ambientales sobre la vejez

    OpenAIRE

    Izal, María; Fernández-Ballesteros, Rocío

    1990-01-01

    La perspectiva ambiental en el estudio de la vejez es probablemente un ámbito poco conocido. En este trabajo se expone una revisión crítica de los principales modelos de explicación de las relaciones ambiente-conducta en la vejez. Finalmente, se discute sobre la superación de algunas limitaciones presentes en estas formulaciones teóricas, presentándose posibles alternativas teóricas y metodológicas para el desarrollo de esta área.

  10. Historicismo: notas sobre um paradigma

    OpenAIRE

    José D’Assunção Barros

    2012-01-01

    Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder,...

  11. Entorno colaborativo sobre laboratorios remotos

    OpenAIRE

    Grosclaude, Eduardo; Sznek, Jorge Eduardo; Ramos Garcia, Vicente; Bertogna, Mario Leandro; López Luro, Francisco; Zanellato, Claudio

    2006-01-01

    El proyecto de investigación Software para Procesos Colaborativos incluye una línea de acción sobre el desarrollo de experiencias en Laboratorios Remotos. Esta línea está dedicada a complementar las tareas de aprendizaje con un soporte tecnológico de sistemas, entendido como todas aquellas actividades de infraestructura que promuevan la disponibilidad de recursos y apoyen la escalabilidad de procesos en la tarea educativa apuntalada por tecnologías de información. En este trabajo se describe ...

  12. Phycocyanin for protecting brain ischemia-reperfusion injury and its effect on the expression of Caspase-3 mRNA

    Institute of Scientific and Technical Information of China (English)

    Xuewei Yang; Yunliang Guo; Hongbing Chen

    2006-01-01

    BACKGROUND: Phycocyanin can anti-oxidize and clear free radial. Whether its protective effect on brain is related to Caspase-3, the promoter and operator of apoptosis, is highly concerned.OBJECTIVE: To observe phycocyanin for protecting nerve function and reducing the size of cerebral infarction of rats with brain ischemia-reperfusion and its effect on the expression of Caspase-3 mRNA.DESIGN: A randomized controlled experiment.SETrING: Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University.MATERIALS: Totally 84 adult healthy female Wistar rats, weighing 210 to 250 g, of clean grade, were provided by the Animal Experimental Center of Shandong University. Phycocyanin (Institute of Oceanography of Chinese Academy of Sciences) was used.METHODS: This experiment was carried out in the Key Laboratory for Prevention and Treatment of Brain Diseases during May to December 2005. ① The rats were randomized into sham-operation group (n=4),control group (n=40) and phycocyanin-treated group (n=40). Middle cerebral artery occlusion/reperfusion (MACO/R) models were created on the rats of control and phycocyanin-treated groups with suture-occluded method by inserting a thread into left side external-internal carotid artery. In the sham-operation group, inserting suture was omitted. After ischemia for 1 hour and reperfusion for 2 hours, suspension of phycocyanin was intragastrically administrated into the rats of the phycocyanin-treated group at 100 mg/kg , and the same volume of normal saline was isochronously administrated into the rats of control group as the same. ② Six rats were chosen respectively from the control group and phycocyanin-treated group, then neurologic impairment degrees of rats were evaluated according to Bederson's grading. ③ Six rats were chosen respectively from the control and phycocyanin-treated groups. The isolated brain tissue was stained with triphenyltetrazolium chloride, and then the size of cerebral

  13. Study on Catalytic Combustion of VOCs over LaMO3 (M = Co, Mn) Perovskite Catalysts%LaMO3(M=Co,Mn)钙钛矿型催化剂上VOCs催化燃烧的研究

    Institute of Scientific and Technical Information of China (English)

    黄海凤; 唐伟; 陈银飞; 陈碧芬

    2004-01-01

    研究了LaMO3(M=Co,Mn)钙钛矿型催化剂对VOCs的催化燃烧性能,该类催化剂对单一VOC和混合VOCs均有很好的催化活性,而LaMnO3的催化活性要比LaCoO3的催化活性更好,氧化还原滴定实验表明,LaMnO3催化剂中锰以Mn4+(大约35%)和Mn3+价态存在,而在LaCoO3催化剂中发现钴均以Co3+价态存在;在混合VOCs催化燃烧的试验中,3种有机物的易氧化性依次为正丙醇>甲苯>环己烷,达到99%的转化率时,环己烷的反应温度则比甲苯的反应温度要约低40℃.

  14. Recursos y enlaces sobre comunidades de aprendizaje

    OpenAIRE

    Ferrer Esteban, Gerard

    2005-01-01

    Obras y artículos sobre el proyecto Comunidades de Aprendizaje desarrollado en el Estado español. Tesis doctorales sobre comunidades de aprendizaje. Fundamentación teórica de las comunidades de aprendizaje. Sitios en Internet relacionados con las comunidades de aprendizaje y proyectos afines de desarrollo comunitario en contextos escolares.

  15. On GAMER, plataforma de continguts sobre videojocs

    OpenAIRE

    Villegas Bonachera, José Ricardo

    2015-01-01

    Desenvolupament d'una plana web amb disseny responsiu sobre videojocs en català a partir del gestor de continguts WordPress. Desarrollo de una página web con diseño responsivo sobre videojuegos en catalán a partir del gestor de contenidos WordPress. Bachelor thesis for the Multimedia program on Computer Science.

  16. Residual strain measurements of a fatigued metal stick and heat treated steel pipe at JRR3M-RESA

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Kazuko; Horikawa, Takeshi; Kawashima, Hisaichi [Ryukoku Univ., Kyoto (Japan); Minakawa, Nobuaki; Tsuchiya, Yoshinori

    1997-06-01

    A residual strain on section of notched edge after fatiguing the carbon steel round bar with ring shape and semi-circular section and on thick direction of 13% Cr-steel pipe for oil well heat-treated after machining was tried to test. It was one of the initial experiments in residual strain measurement apparatus (RESA; old name is DIVE) installed at T2-1 port of JRR-3M to test a residual strain at section of 8 mm in diameter of the fatigue specimen at three (x{sup -}, y{sup -} and z{sup -}) directions on a fine mesh of 1 mm step. This test has another aim to inspect the apparatus itself such as obtained accuracy, required testing time, and so on, except original aim to find out strain of the specimen. As a result of the initial experiment, a lot of points to be investigated and improved were found out. According to these results, at present a fatigue specimen with large diameter (40 mm) is now in preparation. And, as is now processing on improvement of a monochromator to increase the beam intensity and so on, a higher resolution as well as a finer (about 1 micron) beam diameter for the specimen is expected to establish. (G.K.)

  17. The Horizontal Branch in the UV Colour Magnitude Diagrams. II. The case of M3, M13 and M79

    CERN Document Server

    Dalessandro, Emanuele; Ferraro, Francesco R; Mucciarelli, Alessio; Cassisi, Santi

    2012-01-01

    We present a detailed comparison between far-UV/optical colour Magnitude Diagrams obtained with high-resolution Hubble Space Telescope data and suitable theoretical models for three Galactic Globular Clusters: M3, M13 and M79. These systems represents a classical example of clusters in the intermediate metallicity regime that, even sharing similar metal content and age, show remarkably different Horizontal Branch morphologies. As a consequence, the observed differences in the colour distributions of Horizontal Branch stars cannot be interpreted in terms of either first (metallicity) or a second parameter such as age. We investigate here the possible role of variations of initial Helium abundance (Y). Thanks to the use of a proper setup of far-UV filters, we are able to put strong constraints on the maximum Y (Y_{max}) values compatible with the data. We find differences Delta Y_{max} ~ 0.02-0.04 between the clusters with M13 showing the largest value (Y_{max} ~ 0.30) and M3 the smallest (Y_{max} ~ 0.27). In g...

  18. Patterns of mouse reticulon 3 mRNA and protein expression in the mouse central nervous system

    Institute of Scientific and Technical Information of China (English)

    LIU Jin; QIANG Boqin; YUAN Jiangang; HUANG Xiaowei; PENG Xiaozhong; YANG Hongbo; YIN Bin; TAN Xinyu; FAN Ming; FAN Wenhong; LIU Bingyan

    2003-01-01

    Reticulons (RTN) are endoplasmic reticulumassociated protein complexes, which are localized in the endoplasmic reticulum (ER) and identified as markers for neuroendocrine differentiation. At least four different RTN genes have been identified in mammals, but in most cases,the functions of the encoded proteins except mammalian RTN4-A and RTN4-B are still elusive. In the present study,mouse reticulon 3 (mRTN3) is cloned and its expression pattern in a variety of tissues is investigated. Three alternatively spliced transcripts of 1.8, 2.8 and 4.2 kb are revealed by Northern blotting hybridization. The 1.8 and 2.8 kb transcripts are expressed in many tissues. The 2.8 kb transcript has a high level in brain and the 4.2 kb transcript is only found in brain. In situ hybridization and immunohistochemical analysis indicated its high expression in non-glial cells in some particular region of mouse central nervous system, such as hippocampus, sub-thalamus nucleus, thalamus nucleus and cerebrum cortex.

  19. Calculation of design load for the MOD-5A 7.3 mW wind turbine system

    Science.gov (United States)

    Mirandy, L.; Strain, J. C.

    1995-01-01

    Design loads are presented for the General Electric MOD-SA wind turbine. The MOD-SA system consists of a 400 ft. diameter, upwind, two-bladed, teetered rotor connected to a 7.3 mW variable-speed generator. Fatigue loads are specified in the form of histograms for the 30 year life of the machine, while limit (or maximum) loads have been derived from transient dynamic analysis at critical operating conditions. Loads prediction was accomplished using state of the art aeroelastic analyses developed at General Electric. Features of the primary predictive tool - the Transient Rotor Analysis Code (TRAC) are described in the paper. Key to the load predictions are the following wind models: (1) yearly mean wind distribution; (2) mean wind variations during operation; (3) number of start/shutdown cycles; (4) spatially large gusts; and (5) spatially small gusts (local turbulence). The methods used to develop statistical distributions from load calculations represent an extension of procedures used in past wind programs and are believed to be a significant contribution to Wind Turbine Generator analysis. Test/theory correlations are presented to demonstrate code load predictive capability and to support the wind models used in the analysis. In addition MOD-5A loads are compared with those of existing machines. The MOD-5A design was performed by the General Electric Company, Advanced Energy Program Department, under Contract DEN3-153 with NASA Lewis Research Center and sponsored by the Department of Energy.

  20. Control system design for the MOD-5A 7.3 mW wind turbine generator

    Science.gov (United States)

    Barton, Robert S.; Hosp, Theodore J.; Schanzenbach, George P.

    1995-01-01

    This paper provides descriptions of the requirements analysis, hardware development and software development phases of the Control System design for the MOD-5A 7.3 mW Wind Turbine Generator. The system, designed by General Electric Company, Advanced Energy Programs Department, under contract DEN 3-153 with NASA Lewis Research Center and DOE, provides real time regulation of rotor speed by control of both generator torque and rotor torque. A variable speed generator system is used to provide both airgap torque control and reactive power control. The wind rotor is designed with segmented ailerons which are positioned to control blade torque. The central component of the control system, selected early in the design process, is a programmable controller used for sequencing, alarm monitoring, communication, and real time control. Development of requirements for use of aileron controlled blades and a variable speed generator required an analytical simulation that combined drivetrain, tower and blade elastic modes with wind disturbances and control behavior. An orderly two phase plan was used for controller software development. A microcomputer based turbine simulator was used to facilitate hardware and software integration and test.

  1. SOLITONS: Dark spatial optical solitons in planar gradient waveguides in the Z-cut of the 3m symmetry crystals

    Science.gov (United States)

    Frolova, M. N.; Borodin, M. V.; Shandarov, S. M.; Shandarov, V. M.; Larionov, Yu M.

    2003-11-01

    The propagation of light beams is studied in a planar photorefractive waveguide fabricated by high-temperature diffusion of metal ions in the Z-cut substrate of the 3m symmetry crystal. The wave equations are obtained for single-mode light beams with TE and TM polarisations in planar diffusion waveguides, which take into account the two-dimensional distribution of the optical field. Expressions are found for a nonlinear change in the refractive index when the photovoltaic mechanism makes a dominant contribution to the photorefractive effect. The propagation of single-mode light beams is analysed numerically for a Ti:Fe:LiNbO3 waveguide fabricated by the successive diffusion of titanium and iron into lithium niobate. It is shown that single-mode light beams with a smooth amplitude envelope can propagate without significant changes in the region of a dip in the intensity modelling a dark soliton. The relations between the amplitude and width of a dark spatial soliton are obtained for the TM modes of a photorefractive planar waveguide.

  2. Escenarios sobre el orden internacional

    Directory of Open Access Journals (Sweden)

    Luis Dallanegra Pedraza

    2012-01-01

    Full Text Available Luego de las grandes cambios que se dieron con la caída del Muro de Berlín y la desintegración en la URSS, se analizan, desde una perspectiva realista-sistémicaestructural, los componentes que intervienen en la generación del orden mundial, qué factores intervienen y cuáles son las diferentes aspiraciones respecto de las características que debería tener. Se tiene en especial consideración la creciente heterogeneización del sistema y la manera en que actores transnacionales operan como motores del futuro orden, predominando por sobre las posibilidades del actor históricamente dominante: el Estado-Nación. Se estudian las características principales del funcionamiento del sistema internacional y el significado de su marco institucional.

  3. Constitucional sobre la justicia ordinaria

    Directory of Open Access Journals (Sweden)

    José Luis Cea Egaña

    2005-01-01

    Full Text Available El artículo analiza el efecto vinculante y de irradiación de las sentencias del Tribunal Constitucional sobre el conjunto del ordenamiento jurídico y de sus órganos. El autor toma partido por la consideración de la ratio decidendi del fallo como vinculante junto al dictum de la sentencia respectiva. Se plantea la necesidad que la LOC del Tribunal Constitucional explicite los efectos vinculantes de los fallos respecto de los tribunales ordinarios y especiales. Finalmente analiza los efectos de la res iudicata en el ámbito del control reparador de constitucionalidad de preceptos legales en control concreto y en control abstracto.

  4. Historicismo: notas sobre um paradigma

    Directory of Open Access Journals (Sweden)

    José D’Assunção Barros

    2012-08-01

    Full Text Available Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder, combinando-se com a consolidação dos modernos estados-nações. A especificação das características deste paradigma constituem o principal ponto de análise

  5. As monografias sobre plantas medicinais

    Directory of Open Access Journals (Sweden)

    Valdir F. Veiga Junior

    2008-09-01

    Full Text Available As monografias sobre plantas medicinais ou drogas vegetais contêm informações para atender não somente aos órgãos de regulamentação, mas também às empresas industriais farmacêuticas e farmácias, e mesmo ao público consumidor. Este artigo revê as monografias da Comissão E, do American Botanical Council, ESCOP, PDR e da Organização Mundial de Saúde em suas origens, objetivos e formatos. Duas publicações recentemente organizadas pela FIOCRUZ do Rio de Janeiro e as contribuições da Farmacopéia Brasileira também são avaliadas.

  6. Design report for an indirectly cooled 3-m diameter superconducting solenoid for the Fermilab Collider Detector Facility

    International Nuclear Information System (INIS)

    The Fermilab Collider Detector Facility (CDF) is a large detector system designed to study anti pp collisions at very high center of mass energies. The central detector for the CDF shown employs a large axial magnetic field volume instrumented with a central tracking chamber composed of multiple layers of cylindrical drift chambers and a pair of intermediate tracking chambers. The purpose of this system is to determine the trajectories, sign of electric charge, and momenta of charged particles produced with polar angles between 10 and 170 degrees. The magnetic field volume required for tracking is approximately 3.5 m long an 3 m in diameter. To provide the desired δp/sub T/p/sub T/ less than or equal to 1.5% at 50 GeV/c using drift chambers with approx. 200μ resolution the field inside this volume should be 1.5 T. The field should be as uniform as is practical to simplify both track finding and the reconstruction of particle trajectories with the drift chambers. Such a field can be produced by a cylindrical current sheet solenoid with a uniform current density of 1.2 x 106 A/m (1200 A/mm) surrounded by an iron return yoke. For practical coils and return yokes, both central electromagnetic and central hadronic calorimetry must be located outside the coil of the magnet. This geometry requires that the coil and the cryostat be thin both in physical thickness and in radiation and absorption lengths. This dual requirement of high linear current density and minimal coil thickness can only be satisfied using superconducting technology. In this report we describe the design for an indirectly cooled superconducting solenoid to meet the requirements of the Fermilab CDF. The components of the magnet system are discussed in the following chapters, with a summary of parameters listed in Appendix A

  7. Activity identification of chimeric anti-caspase-3 mRNA hammerhead ribozyme in vitro and in vivo

    Institute of Scientific and Technical Information of China (English)

    XU; Renhuan; (

    2001-01-01

    [1]Andrew, F., Gerard, E., A license to kill, Cell, 1996, 85: 781-784.[2]Thornberry, N. A., Lazebnik, Y., Caspases: Enemies within, Science, 1998, 281: 1312-1316.[3]Kijima, H., Ishida, H., Ohkawa, T. et al., Therapeutic application of ribozymes, Pharmacol. Ther., 1995, 68: 247-264.[4]Phylactou, L. A., Kilpatrick, M. W., Wood, M. J., Ribozymes as therapeutic tools for genetic disease, Hum. Mol. Genet., 1998, 7(10): 1649-1653.[5]Bettrand, E., Pictet, R ., Grange, T., Can heamerhead ribozymes be efficient tools inactivate gene function? Nucleic Acids Res., 1994, 22: 293-300.[6]Lieber, A., Strauss, M., Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library, Mol. Cell Biol., 1995, 15: 540-551.[7]Xu, R. H., Zhou, X. Q., Xie, Q. et al., Preparation and identification of hammerhead ribozyme in vitro against rat caspase-3 mRNA fragment, Chin. J. Hepatol., 2000,8: 361-363.[8]Liu, J., Jin, Y. X., Wang, D. B., A novel vector for abundant expression of antisense RNA, triplex-forming RNA and ribozyme in vivo, High Technology Letters, 2000, 6: 84-88.[9]Sambrook, J., Fritsch, E. F., Maniatis, T., Molecular Cloning: A Laboratory Manual, 2nd ed., New York: Cold Spring Harbor Laboratory Press, 1989.[10]Porter, A. G., J?nicke, R. U., Emerging roles of caspase-3 in apoptosis, Cell Death Differ, 1999, 6: 99-104.[11]Cryns, V., Yuan, J., Proteases to die for, Genes Dev., 1998, 12: 1551-1570.[12]Narendra, K. V., Anikumar, R. K., Fritz, E., Recent developments in the hammerhead ribozyme field, Nucleic Acids Research, 1998, 26: 5237-5242.

  8. Detailed DFT studies of the electronic structure and optical properties of KBaMSe{sub 3} (M = As, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Azam, Sikander; Khan, Saleem Ayaz; Khan, Wilayat [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Muhammad, Saleh; Udin, Haleem [Materials Modeling Lab, Department of Physics, Hazara University, Mansehra (Pakistan); Murtaza, G., E-mail: murtaza@icp.edu.pk [Materials Modeling Laboratory, Department of Physics, Islamia College University, Peshawar (Pakistan); Khenata, R., E-mail: khenata_rabah@yahoo.fr [Laboratoire de Physique Quantique et de Modélisation Mathématique (LPQ3M), Département de Technologie, Université de Mascara, Mascara 29000 (Algeria); Shah, Fahad Ali [Materials Modeling Lab, Department of Physics, Hazara University, Mansehra (Pakistan); Minar, Jan [New Technologies – Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Ahmed, W.K. [ERU, College of Engineering, United Arab Emirates University, Al Ain (United Arab Emirates)

    2015-09-25

    Highlights: • The compounds are studied by FP-LAPW method within LDA, GGA, EV-GGA approximations. • All the compounds show indirect band gap nature. • Bonding nature is mixed covalent and ionic. • High absorption peaks and reflectivity ensures there utility in optoelectronic devices. - Abstract: Bonding nature as well as the electronic band structure, electronic charge density and optical properties of KBaMSe{sub 3} (M = As, Sb) compounds have been calculated using a full-potential augmented plane wave (FP-LAPW) method within the density functional theory. The exchange–correlation potential was handled with LDA and PBE-GGA approximations. Moreover, the Engel–Vosko generalized gradient approximation (EV-GGA) and the modified Beck–Johnson potential (mBJ) were also applied to improve the electronic band structure calculations. The study of band structure shows that KBaAsSe{sub 3}/KBaSbSe{sub 3} compounds have an indirect band gap of 2.08/2.10 eV which are in close agreement with the experimental data. The bonding nature has been studied as well using the electronic charge density (ECD) contour in the (1 0 1) crystallographic plane. It has been revealed that As/Sb–O atoms forms a strong covalent, while Ba–Se atoms form weak covalent bonding and the ionic bonding is mainly found between K and Ba atoms. Moreover, the complex dielectric function, absorption coefficient, refractive index, energy-loss spectrum and reflectivity have been estimated. From the reflectivity spectra, we found that KBaAsSe{sub 3} compound shows greater reflectivity than KBaSbSe{sub 3}, which means that KBaAsSe{sub 3} compound can be used as shielding material in visible and also in ultra violet region.

  9. Site-preferential design of itinerant ferromagnetic borides: experimental and theoretical investigation of MRh6B3 (M = Fe, Co).

    Science.gov (United States)

    Misse, Patrick R N; Gillessen, Michael; Fokwa, Boniface P T

    2011-10-17

    Single-phase polycrystalline samples of the compounds MRh(6)B(3) (M = Fe, Co) as well as single crystals of CoRh(6)B(3) have been synthesized by arc-melting the elements under a purified argon atmosphere in a water-cooled copper crucible. The characterization of the new phases was achieved by using single-crystal and powder X-ray diffraction as well as EDX measurements. The two phases are isotypic and crystallize in the hexagonal Th(7)Fe(3) structure type (space group P6(3)mc, no. 186, Z = 2). In this structure, the magnetically active atoms (Fe, Co) are preferentially found on only one of the three available rhodium sites, and together with rhodium they build a three-dimensional network of interconnected (Rh/M)(3) triangles. Magnetic properties investigations show that both phases order ferromagnetically below Curie temperatures of 240 K (for FeRh(6)B(3)) and 150 K (for CoRh(6)B(3)). First-principles DFT calculations correctly reproduce not only the lattice parameters but also the ground state magnetic ordering in the two phases. These calculations also show that the long-range magnetic ordering in both phases occurs via indirect ferromagnetic coupling between the iron atoms mediated by rhodium. This magnetic structural model also predicts the saturation magnetizations to be 4.02 μ(B) for FeRh(6)B(3) (3.60 μ(B) found experimentally) and 2.75 μ(B) for CoRh(6)B(3). Furthermore, both phases are predicted to be metallic conductors as expected for these intermetallic borides. PMID:21905755

  10. Synthesis of LaMO{sub 3} (M = Fe, Co, Ni) using nitrate or nitrite molten salts

    Energy Technology Data Exchange (ETDEWEB)

    Yang Jun, E-mail: tyangj@jnu.edu.c [Department of Chemistry, Jinan University, Shipai, Guangzhou, Guangdong Province 510632 (China); Li Runsheng; Zhou Junyi; Li Xiaoci; Zhang Yuanming; Long Yulin [Department of Chemistry, Jinan University, Shipai, Guangzhou, Guangdong Province 510632 (China); Li Yongwang [State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Sciences, Taiyuan 030001 (China)

    2010-10-22

    Research highlights: {yields} The molten salt, synthesis temperature, the oxidising properties, the basicity and oxidation states of the melt play an important role in LaMO{sub 3} synthesis. {yields} The system needs a careful optimisation of these parameters to obtain pure orthorhombic LaFeO{sub 3}, hexagonal LaCoO{sub 3} and LaNiO{sub 3}. Purely hexagonal LaNiO{sub 3} nanocrystals were successfully synthesized. {yields} SEM analyses were taken to investigate how the different parameters affect the microstructure of the samples. {yields} The specific surface area and crystallite size of LaMO{sub 3} show much difference in different system. - Abstract: Perovskite compound LaMO{sub 3} (M = Fe, Co, Ni) nanocrystals were successfully synthesized in molten nitrates or nitrites from a mixture of lanthanum nitrate and an M-containing nitrate for 2 h. The effect of the various process parameters on the phase purity, crystallite size, specific surface area and morphology of the synthesized nanocrystals were systematically studied by XRD, scanning electron microscopy (SEM), simultaneous TG/DSC and BET measurements. The results showed that salt medium, annealing temperatures (mainly 450-850 {sup o}C), oxidising properties and basicity of the melt played an important role in the synthesis of LaMO{sub 3}. The addition of Na{sub 2}O{sub 2} facilitated the reaction between La{sub 2}O{sub 3} and NiO or Co{sub 3}O{sub 4}, leading to the formation of LaNiO{sub 3} and LaCoO{sub 3} at a much lower temperature of 450 {sup o}C. Pure hexagonal LaNiO{sub 3} nanocrystals were obtained in molten NaNO{sub 3}-KNO{sub 3} eutectic with Na{sub 2}O{sub 2} at 550-750 {sup o}C.

  11. Puente sobre el rio Medway

    Directory of Open Access Journals (Sweden)

    Freeman, Fox, Ingenieros

    1963-02-01

    have been prestressed both longitudinally and transversally. Between the two circulation roadways an elastic barrier has been placed, supported on metal posts.El puente sobre el río Medway tiene la misión de salvar dicho río en el nuevo trazado de carretera necesario para aliviar el denso tráfico estival entre Dower y Londres. Está situado en las proximidades de la ciudad de Rochester. La estructura se ha construido utilizando las vías de concurso. De todos los tipos presentados se eligió una estructura de hormigón armado. La longitud total de la obra es de 1.000 m. Los tres tramos principales de la obra salvan el río. El central es de 152 m de luz, y los dos adyacentes son de 103 m cada uno. Los accesos tienen un total de 18 tramos, que arrojan una longitud de 654 m. La anchura del puente es de 34 m, y la calzada se ha subdividido en dos direcciones de tráfico de 7,30 m cada una y, además, se han dejado dos espaldones laterales de 2,40 m de anchura. En planta se puede admitir que el puente tiene una alineación recta con una ligerísima curva, y que en el plano vertical presenta una pendiente de desagüe entre las pilas 9 y 10. Los estribos son de hormigón armado: tipo celular el del este y de hormigón en masa el del oeste. Los estribos se apoyan sobre pilotes hexagonales de hormigón armado cuya circunferencia circunscrita tiene 55 cm de radio y de 12 a 20 m de longitud. Cuando el firme se hallaba a profundidades inferiores a 6 m, los estribos se cimentaban directamente sobre el firme. Las pilas constituyen pórtico y tienen una altura variable de 9 a 30 m sobre el nivel del suelo. Los tramos de acceso forman una estructura continua simplemente apoyada. Cada tramo se compone de ocho vigas longitudinales de 30 a 41 m de longitud y de 190 toneladas cada una. Estas vigas son del tipo pretensado y prefabricado. El tramo central es del tipo cantilever, constituido por dos brazos, de 30 m de longitud, formados por vigas cajón. Cada una de estas vigas consta

  12. FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis

    DEFF Research Database (Denmark)

    Ryder, L Rebekka; Bartels, Else Marie; Woetmann, Anders;

    2012-01-01

    Our aim was to elucidate the relative amount of the different splice forms of FoxP3 mRNA in CD4+ T cells in peripheral blood (PB) compared to synovial fluid (SF) in RA and PsA patients. FoxP3 mRNA was measured using a quantitative real-time PCR method. CD4+ T cells were isolated from 17 paired sa...

  13. Puente sobre el Oosterschelde, Holanda

    Directory of Open Access Journals (Sweden)

    Hoving, H. T.

    1967-03-01

    Full Text Available This new bridge, forming part of the Delta project, is made of concrete, and was built by successive overhangs. Precast units were mainly used. The bridge is 5,000 m long, and is 11.85 m wide. The main spans are 95 m in length, except one, which can be opened up to sea traffic, which is 40 m long. The free height of the bridge over the sea is 15 m, which is insufficient for large ships. This required that one of the spans, in deep water, should open up, on hinges, and provide free passage to large ships. The intermediate bridge supports are of special interest. They rest on piles which go down to 38 m. They are hollow, cylindrical, of 4.35 m external diameter, and are driven into the ground in several stages, as they penetrate through the sands at the bottom of the Oosterschelde. To drive them in, an excavating device, inside the pile, was utilised, and also a dredging and suction mechanism, to clean out the bottom, and allow the piles to sink by gravity. But when external friction did not allow this to happen, the piles were weighed down with up to 500 tons of ballast. A series of three of these piles, in a row, makes up each bridge support. A cross member over the pile heads supports, in turn, the bridge deck. The bridge was built in successive sections, overhanging from each support, and then finally connected with a central portion. Use of precast units has been very extensive, so that the bridge can be justiaflably regarded as being prefabricated.Este nuevo puente, que forma parte del Plan de obras denominadas del Delta, es de hormigón y se ha construido por el procedimiento de voladizos sucesivos, utilizando, en su mayor parte, elementos prefabricados. Tiene una longitud total de 5.000 m; una anchura de 11,85 m; tramos principales de 95 m de luz, salvo uno, levadizo, que tiene 40 m. La altura libre sobre las ag^uas del mar es de 15 m, que es insuficiente para las naves de gran tonelaje; esto exigió que uno de sus tramos, en aguas

  14. Somos un envase : Discursos sobre el aborto

    OpenAIRE

    Löcher, Jennifer Irene

    2014-01-01

    No hay persona que no tenga opinión acerca del asunto y, cada vez más, la sociedad argentina debate sobre la pregunta de si se debe legalizar/despenalizar el aborto o no. Nunca antes se habló tanto sobre el tema públicamente: se publican artículos en los diarios, hay manifestaciones a favor y hay manifestaciones en contra de la legalización del aborto. El siguiente trabajo pretende relevar y analizar discursos que circulan socialmente alrededor del debate sobre el aborto. (Párrafo extraíd...

  15. Concepciones sobre la docencia universitaria de calidad

    OpenAIRE

    Arbeláez López, Ruby; Fortes del Valle, M. Carmen; Grau Rubio, Claudia

    2008-01-01

    Con esta investigación hemos querido participar en el proceso de búsqueda y construcción del sentido de calidad aplicado a la docencia universitaria, con el objetivo general de evidenciar las concepciones sobre docencia de calidad que pueden deducirse de los procesos de evaluación de los profesores universitarios. Nuestra meta final intenta propiciar la revisión de las políticas educativas y el enriquecimiento de la cultura sobre docencia y sobre evaluación docente. La mayor aportación de nue...

  16. CAST3M/ARCTURUS: a coupled heat transfer / CFD code for thermal-hydraulic analyses of gas cooled reactors

    International Nuclear Information System (INIS)

    , heat exchangers...) are highly recommended. Nevertheless, in case of a total loss of station service power, the safety demonstration of the concept should be guaranteed by natural circulation decay heat removal. This could be performed by keeping a relatively high back-up pressure for pure He natural convection and also by heavy gas injection. So, it also necessary to compute the mixing of different gases and the on-set of natural convection. In this paper, we will report on the developments of the CAST3M/ARCTURUS thermal-hydraulics code developed at CEA, including its coupling to the neutronics code CRONOS2 and the system code CATHARE. Elementary validation cases will be detailed, as well as application of the code to benchmark problems such as the GT-MHR or the HTTR. Examples of thermal-hydraulic calculations decay heat removal of fast reactors designs (GCFR) will also be described. (authors)

  17. Overview of the O3M-SAF validation facility for operational GOME-2 NO2 column data

    Science.gov (United States)

    Pinardi, Gaia; Lambert, Jean-Christopher; Granville, Jos; van Roozendael, Michel; Delcloo, Andy; Debacker, Hugo; Valks, Pieter; Hao, Nan

    In the framework of EUMETSAT's Satellite Application Facility on Ozone and Atmospheric Chemistry Monitoring (O3M-SAF,) nitrogen dioxide (NO2) total column and tropospheric column data are generated operationally from GOME-2 measurements in near-real-time (within 2:30 hours after sensing). NO2 column data are retrieved from the Earth radiance and solar irradiance spectra by a chain of several modules (currently, the level-0-to-1 processor v4.0 and the level-1-to-2 DOAS retrieval processor GDP v4.3). These intermediate modules calculates the parameters needed to derive the final column data: the slant column density along the optical path, the fractional cover and top pressure of clouds affecting the measurement scene, the geometrical enhancement factor (AMF, needed to convert slant into vertical columns), and the NO2 stratospheric reference to be subtracted from the total column to obtain the tropospheric column. In order to validate the final product (the total and tropospheric NO2 columns) in the best way, and due to the complexity of the GOME-2 retrieval chain and the existing issues related to the set-up of a validation strategy in an operational environment, an end-to-end validation ap-proach has been developed, as recommended by Reference Protocols and Guidelines. To ensure meaningful and continuous quality assessment of GOME-2 NO2 data products, the end-to-end validation approach performs the verification and validation of critical individual components of the level-1-to-2 retrieval chain. Particular interest is given to recurring validation issues, such as the particular way remote sensing samples and smoothes the significant variability of atmospheric NO2, the diurnal cycle of NO2, the poor availability of correlative measure-ments (especially for tropospheric column), as well as the current lack of homogenisation of the validation methods. The end-to-end validation process of GOME-2 NO2 data is based on a set of correlative obser-vations performed by

  18. Sobre a psicopatologia dos atos

    Directory of Open Access Journals (Sweden)

    Roberto Calazans

    2015-07-01

    Full Text Available Este artigo pretende apresentar a psicopatologia dos atos a partir do esquema de Jacques Lacan sobre a angústia. Diferenciamos os acting-out, a passagem ao ato, os sintomas, as inibições e a angústia fazendo uma duplicação do esquema de Lacan levando em consideração os registros do simbólico, do real e do imaginário. Esse esquema permite uma abordagem da questão dos atos do sujeito sem cair em uma perplexidade do clínico, nem na confusão entre os atos e a ação. Permite também uma melhor orientação do clínico em relação às diversas modalidades de respostas subjetivas que não se restringem à questão sintomática, que é o campo inaugural da clínica psicanalítica desde a sua fundação por Sigmund Freud. Acreditamos contribuir, assim, para um maior esclarecimento desse esquema no ensino de Lacan e para que ele possa servir de orientação para o tratamento dos atos do sujeito na clínica.

  19. Estudo multicasos sobre atividades inovativas

    Directory of Open Access Journals (Sweden)

    Sonia Regina Hierro Parolin

    2013-09-01

    Full Text Available Em estudos sobre competitividade argumenta-se que as empresas necessitam de estratégias baseadas em inovações e de capacidades internas em constantes e intensas transformações, não somente nos padrões tecnológicos, mas também no encadeamento do processo de gestão das atividades inovativas, como processos dinâmicos, não lineares e diversificados, em função de múltiplos fatores dos ambientes interno e externo. Para contribuir com essas discussões, neste artigo apresenta-se um estudo multicasos em quatro indústrias de médio e grande portes, de segmentos, densidades tecnológicas e históricos com inovações diferentes entre si. Como principais resultados, salientam-se o encadeamento das atividades inovativas como parte de uma estratégia organizacional para obter resultados com inovação e a afluência de todas as pessoas, e não somente as alocadas em pesquisa e desenvolvimento, para o cumprimento dessa estratégia.

  20. PERSPECTIVAS INFANTILES SOBRE LA TERRITORIALIDAD

    Directory of Open Access Journals (Sweden)

    Noelia Enriz

    2009-12-01

    Full Text Available En este trabajo nos proponemos un acercamiento a las diversas ideas infantiles sobre el territorio habitado, en el contexto particular de la población mbyá guaraní de Misiones. La fragilidad territorialidad a la que es expuesta la población indígena en Argentina se manifiestan cotidianamente en diversas áreas. La población mbyá, ha sido surcada por los límites de los estados nacionales de Paraguay, Brasil y Argentina. La sedentarización y los cercamientos de tierras en los diferentes estados, han impulsado transformaciones de las lógicas de subsistencia, de habitación y organización comunitaria. En el caso de la provincia de Misiones la acreditación burocrática de los títulos de tierras se encuentra aplazada, el estado no se compromete con la concreción de este derecho.

  1. Puente colgante sobre el Lillebaelt

    Directory of Open Access Journals (Sweden)

    Ostenfeld, Chr.

    1971-09-01

    Full Text Available This bridge, which was opened to traffic in October 1970 over the Lillebaelt, is the first of its kind in Denmark. It consists of a central span of 600 m, and two lateral ones of 240 m length each. The suspension cables, each 1,500 m, are the world's largest prefabricated cables. The bridge has original features, such as flaps on the main box girder, and new design of the anchorage blocks. These and other details are described in the article.Inaugurado en octubre de 1970, el puente colgante sobre el Lillebselt es el primer puente danés de este tipo. Consta de un tramo central de 600 m y dos tramos laterales de 240 m. Los cables sustentantes son, con sus 1.500 m de longitud, los mayores cables prefabricados del mundo. El puente presenta características origínales —empleo de «flaps» en la vigacajón de la superestructura, concepción nueva de los macizos de anclaje...— que, junto con el sistema de ejecución y las demás particularidades de la obra, son descritas en el artículo.

  2. Los derechos de autor sobre obtenciones vegetales

    Directory of Open Access Journals (Sweden)

    Rosario Silva Gilli

    2015-01-01

    Full Text Available Contenido: Las creaciones en la agricultura. Los derechos de autor sobre obtenciones vegetales. El Convenio Internacional para la protección de las obtenciones vegetales (París 1961 y sus revisiones de Ginebra 1972, 1978,1991 Objeto de la protección legal. Condiciones del cultivar. Alcance de la protección. La protección de obtenciones vegetales en el Mercosur. Los Derechos de autor en el Mercosur. El Protocolo de Armonización de normas sobre Propiedad Intelectual en el Mercosur. El Acuerdo de Cooperación y facilitación sobre la protección de las obtenciones vegetales en los Estados Partes del Mercosur.  Alcance de la normativa Mercosur. Los Derechos sobre cultivares en Uruguay. Los Derechos de autor como derechos humanos. ¿Derechos de autor vs. derecho de propiedad intelectual? Reflexión final

  3. Analysis of CD4+CD25+ Regulatory T Cells and Foxp3 mRNA in the Peripheral Blood of Patients with Asthma

    Institute of Scientific and Technical Information of China (English)

    XUE Keying; ZHOU Yongming; XIONG Shengdao; XIONG Weining; TANG Tao

    2007-01-01

    The changes of CD4+CD25+ regulatory T cells (CD4+CD25+ Treg) and Foxp3 mRNA in peripheral blood mononuclear cells (PBMCs) from patients with asthma were investigated in order to elucidate the possible roles of CD4+CD25+ Treg in the development of asthma. The peripheral blood samples were collected from 29 healthy controls (normal control group) and 78 patients with asthma which included 30 patients in exacerbation group, 25 patients in persistent group, and 23 patients in remission group. By using flow cytometry and RT-PCR, the CD4+CD25+ Treg ratio and Foxp3 mRNA in PBMCs were detected. The CD4+CD25+ Treg ratio and Foxp3 mRNA in PBMCs of exacerbation and persistent groups were lower than that of remission and normal control groups (P<0.05). Although the CD4+CD25+ Treg ratio and Foxp3 mRNA of remission group were also lower than that of normal control group, there was no significant difference between them (P>0.05). As compared with persistent group, exacerbation group had lower CD4+CD25+ Treg ratio and Foxp3 mRNA (P<0.05). It was indicated that the decrease of CD4+CD25+Treg ratio and its function in PBMCs may be responsible for pathogenesis of asthma.

  4. PERSPECTIVAS INFANTILES SOBRE LA TERRITORIALIDAD

    Directory of Open Access Journals (Sweden)

    NOELIA ENRIZ

    2009-12-01

    Full Text Available In this paper we propose a different approach to children's ideas about the geographical area in the particular context of the Mbyá Guarani population, from Misiones (Argentine. The territorial fragility, that is exposed to the indigenous people in Argentina aremanifested daily in several areas. Mbyá population, has been crossed by the boundaries of national states of Paraguay, Brazil and Argentina. The sedentary and enclosures land processes in different states, have prompted changes in the logic of subsistence, housing and community organization. In Misiones province case, bureaucratic accreditation of land titles is postponed, the state is not committed to the realization of this right.RESUMEN: En este trabajo nos proponemos un acercamiento a las diversas ideas infantiles sobre el territorio habitado, en el contexto particular de la población mbyá guaraní de Misiones. La fragilidad territorialidad a la que es expuesta la población indígena en Argentina se manifiestan cotidianamente en diversas áreas. La población mbyá, ha sido surcada por los límites de los estados nacionales de Paraguay, Brasil y Argentina. La sedentarización y los cercamientos de tierras en los diferentes estados, han impulsado transformaciones de las lógicas de subsistencia, de habitación y organización comunitaria. En el caso de la provincia de Misiones la acreditación burocrática de los títulos de tierras se encuentra aplazada, el estado no se compromete con la concreción de este derecho.

  5. Consideraciones preliminares sobre la credibilidad

    Directory of Open Access Journals (Sweden)

    Fernando Verdugo

    2004-01-01

    Full Text Available A modo de introducción al Seminario Interno de Profesores de la Facultad de Teología de la PUC, el autor recuerda, en primer lugar, lo que suele entenderse por "credibilidad" y, también, algunos de los criterios generales por los cuales algo o alguien adquiere la calidad de creíble (el que sea razonable, relevante o significativo, capaz de producir gozo estético, etc.. Luego, en la parte más extensa, el autor vuelve a llamar la atención sobre la necesidad de atender a los condicionamientos culturales de la fe cristiana. La fe, al igual que toda experiencia humana, está culturalmente mediada. Tomar conciencia de ese hecho y asumir las consecuencias metodológicas es indispensable para una teología que quiere poner atención a los desafíos actuales y contribuir así a la credibilidad del cristianismoThis article reprints the introductory session to the internal seminar of lecturers from the Faculty of Theology of the UC. In the first place, the author sums up what is usually understood by `credibility' and the general criteria through which something or someone gains credibility (being reasonable, relevant or significant, capable of producing aesthetic pleasure. Then the author deals at length with the need to take notice of the cultural conditionings of the Christian faith. The faith, the same as any other human experience, is culturally mediated. It is crucial for theology to become aware of this fact and come to terms with its methodological consequences, if it wants to face current challenges and so contribute to the credibility of Christianity

  6. Ligand exchange and complex formation kinetics studied by NMR exemplified on fac-[(CO)3M(H2O)]+ (M = Mn, Tc, Re)

    OpenAIRE

    Helm, Lothar

    2008-01-01

    In this review ligand exchange and complex formation reactions on fac-[(CO)3M(H2O)3]+ (M = Mn, Tc, Re) and on fac-[(CO)2(NO)Re(H2O)3]2+ are presented. A variety of experimental NMR techniques are described and it is shown that sometimes combinations of techniques applied at variable temperature or variable pressure allowed to measure exchange rate constants and their activation parameters as well as thermodynamic parameters. Furthermore, the use of uncommon nuclei for NMR like 17O or 99Tc ext...

  7. TNFAIP3 mRNA及其蛋白在尿路上皮乳头状癌组织中的表达与临床意义

    Institute of Scientific and Technical Information of China (English)

    杨慧敏; 段秀枝; 吴秀玲; 沈默; 万丽; 翁志梁; 余志贤; 陶志华

    2012-01-01

    目的探讨肿瘤坏死因子α诱导蛋白3(TNFAIP3)在膀胱尿路上皮乳头状癌(UPC)组织中的表达及临床意义。方法用实时荧光定量PCR方法和免疫组化Envision法分别检测62例UPC组织及20例正常膀胱组织标本中TNFAIP3 mRNA和蛋白的表达情况,ROC曲线对TNFAIP3 mRNA诊断UPC的价值进行分析,并结合患者的临床资料分析TNFAIP3的表达与UPC临床参数的关系。结果 TNFAIP3 mRNA及其蛋白在UPC中的表达均高于正常组织(P均<0.05)。TNFAIP3 mRNA ROC曲线下面积(AUC)为0.811,当TNFAIP3 mRNA/GAPDH mRNA×10~4的cutoff为0.89时,TNFAIP3 mRNA诊断UPC的敏感度和特异度分别为72.6%和85.0%;另外,TNFAIP3 mRNA及其蛋白的表达与UPC的病理分级,肿瘤浸润及淋巴结转移密切相关(P均<0.05),但与患者的性别,年龄无关(P均>0.05)。结论 TNFAIP3 mRNA及其蛋白在膀胱UPC组织中表达上调,并与肿瘤的分级,浸润和转移相关,提示其可能参与了膀胱肿瘤的发生和发展,是有价值的膀胱肿瘤新的标记物。

  8. DISERTACIÓN SOBRE JUSTICIA Y EQUIDAD

    Directory of Open Access Journals (Sweden)

    Sayuri P. Tamura M.

    2001-01-01

    Full Text Available «Disertación sobre equidad y justicia» es básicamente una respuesta a una inquietud en particular que yo tenía sobre las distintas posiciones que existen sobre estos dos temas y cómo definir cuál es la más acertada. Hice una descripción del punto de vista de Amartya Sen –la violación de los derechos sobre la propiedad privada es justificable si evitan las hambrunas2– frente al de Robert Nozick –la propiedad privada es un derecho fundamental y como tal debe ser respetado3–, sin embargo, aunque ambos enfoques son totalmente contrarios tienen mucho sentido, por lo cual es bastante difícil decidirse por uno en particular. Fue de esta forma, enfrentando sus opiniones, que yo logré desarrollar una posición frente a estas dos perspectivas, y así dar mi opinión al DISERTACIÓN SOBRE JUSTICIA Y EQUIDAD SAYURI P. TAMURA M. Estudiante de Economía y Negocios Internacionales de la Universidad ICESI. respecto. Al final, llegué a una conclusión, que aunque no es la más original y tampoco es la única, tiene mucho sentido y seguramente de ser posible, la situación del país podría cambiar para bien.

  9. 1.3 m m InGaAsN/ GaAs Lasers Grown by MOCVD Using TBAs and DMHy Sources

    Institute of Scientific and Technical Information of China (English)

    Gray Lin; C. M. Lu; C. H. Chiou; I. F. Chen; T. D. Lee; J. Y. Chi; D.A. Livshits

    2003-01-01

    We have demonstrated InGaAsN/ GaAs single quantum well (SQW) lasers grown by MOCVD using TBAs and DMHy sources. For un-buffer-strained InGaAsN/ GaAs system, our SQW lasers of 1.3 m m range is among the best in terms of transparency and threshold current density.

  10. The Inhibitory Effects of an Antisense u-PAR Vector on Invasion of Highly Invasive Human Prostate Carcinoma PC-3M Cell Subclones

    Institute of Scientific and Technical Information of China (English)

    廖国宁; 李清芬; 冯友梅; 邓耀祖; 李卓娅; 龚非力; 马丁

    2003-01-01

    Summary: To observe the inhibitory effects of an antisense u-PAR vector on invasion of highly inva-sive PC-3M cell subclones, the effects of the antisense u-PAR on activity of MMP-9 in those highlyinvasive cell subclones were detected by a quantitative RT-PCR and zymography. The monolayer in-vasion assay and colony formation assay in soft agar were used. And tumorigenesis rate and invasionsby the cell subclones with or without the antisense u-PAR were observed in nude mice. It was foundthat in vitro growth of highly invasive PC-3M cell subclones transfected with the antisense u-PARwas declined, and the ability of anchorage-independent growth of those cell subclones was found de-creased sharply, with the inhibiting rate becoming 79 % and 60 %, respectively. Although the anti-sense u-PAR didn't change MMP-9 gene transcription, they could inhibit the activation of MMP-9 ofhighly invasive PC-3M cell subclones. Moreover, the tumorigenesis rate of the cell subclones with theantisense u-PAR decreased and the growth of a neoplasm also slowed down. Thet tests showed thedifference between experimental and control groups was statistically significant (P<0. 01). The anti-sense u-PAR vector could not only inhibit the invasion ability of highly invasive PC-3M cell subclonesin vitro but also restrain the growth of those cell subclones in vivo.

  11. Developmentally Regulated Expression of HDNF/NT-3 mRNA in Rat Spinal Cord Motoneurons and Expression of BDNF mRNA in Embryonic Dorsal Root Ganglion.

    Science.gov (United States)

    Ernfors, Patrik; Persson, Håkan

    1991-01-01

    Northern blot analysis was used to demonstrate high levels of hippocampus-derived neurotrophic factor/neurotrophin-3 (HDNF/NT-3) mRNA in the embryonic day (E) 13 - 14 and 15 - 16 spinal cord. The level decreased at E18 - 19 and remained the same until postnatal day (P) 1, after which it decreased further to a level below the detection limit in the adult. In situ hybridization revealed that the NT-3 mRNA detected in the developing spinal cord was derived from motoneurons and the decrease seen at E18 - 19 was caused by a reduction in the number of motoneurons expressing NT-3 mRNA. The distribution of NT-3 mRNA-expressing cells in the E15 spinal cord was very similar to the distribution of cells expressing choline acetyltransferase or nerve growth factor receptor (NGFR) mRNA. Moreover, a striking similarity between the developmentally regulated expression of NT-3 and NGFR mRNA was noted in spinal cord motoneurons. A subpopulation of all neurons in the dorsal root ganglia expressed brain-derived neurotrophic factor (BDNF) mRNA from E13, the earliest time examined, to adulthood. These results are consistent with a trophic role of NT-3 for proprioceptive sensory neurons innervating the ventral horn, and imply a local action of BDNF for developing sensory neurons within the dorsal root ganglia. PMID:12106253

  12. Rastros: dizendo sobre os fazeres/dizeres

    OpenAIRE

    MELLO MARISOL BARENCO CORRÊA DE

    2001-01-01

    Com vistas ao aclaramento de noções erroneamente herdadas do contexto social e histórico da cultura moderna ocidental, que teve/tem como um de seus projetos o "apagamento" do sujeito, ou o distanciamento entre os sujeitos e suas formas de fazer, dizer, pensar, este artigo pretende contribuir com elementos para a construção de um outro paradigma nas ciências humanas. Trata-se de um relato sobre o processo de construção de nossa própria pesquisa, articulado à reflexão sobre as diversas formas d...

  13. Sobre la esclavitud: libro de artista

    OpenAIRE

    MACHADO JIMÉNEZ, ALBERTO

    2015-01-01

    Sobre la esclavitud es un libro de artista, donde encontraremos imágenes acompañadas de breves frases que hacen referencia al tema propuesto en cada ilustración para que así se pueda comprender mejor la intención de este trabajo, reflexionar sobre la manera que tenemos de ver las cosas, en este caso, con respecto a la esclavitud. Dar a conocer distintas formas de ser esclavo en este sistema sería uno de los objetivos principales. Hacer litografías, dibujos con el uso de acua...

  14. Consideraciones sobre diferentes procesos productivos y sus consecuencias sobre el medio ambiente

    OpenAIRE

    Caridad Ramos Alvariño

    2004-01-01

    En el presente trabajo se exponen algunas consideraciones sobre diferentes procesos productivos y sus consecuencias sobre el medio ambiente. La disminución del impacto negativo de algunas producciones sobre el medio ambiente es favorable, pero el problema va más allá y de lo que se trata es de la necesidad de una transformación sostenible de las producciones que puedan conducir a una vida agradable y una naturaleza conservada entre otras muchas cuestiones que agobian hoy al mundo. La solución...

  15. Influência do "primer" sobre o esmalte na resistência ao cisalhamento de sistemas adesivos

    OpenAIRE

    RUSSO Eliza Maria Agueda; Garone NETTO Narciso; Rubens Corte Real de CARVALHO; Márcio Garcia dos SANTOS

    1998-01-01

    A proposta deste estudo foi comparar a adesão ao esmalte de dois sistemas adesivos de frasco único com sistemas que usam "primer" e "bond" separadamente, com o objetivo de verificar se a força de adesão da resina composta ao esmalte é influenciada pela presença do "primer" de dentina sobre o esmalte. Foram avaliados quatro sistemas adesivos: ONE STEP (Bisco), PRIME & BOND (Dentsply), SCOTCHBOND MULTI-PURPOSE PLUS (3M) e PROBOND (Dentsply). Molares humanos foram seccionados no sentido ocluso-c...

  16. Las fuentes cristianas sobre Jesús

    Directory of Open Access Journals (Sweden)

    Melero Martínez, J.M.

    2010-01-01

    Full Text Available El artículo es una presentación de las fuentes históricas sobre Jesús de Nazaret: fuentes sinópticas, fuente Q, fuentes afines a la gnosis, fragmentos de evangelio con material sinóptico o joánico, evangelios judeocristianos y otras fuentes.

  17. Sobre un sistema no lineal de epidemias

    OpenAIRE

    Ortega S., Luis

    2012-01-01

    Un modelo sobre epidemias que describe la población infectada y la población susceptible de ser infectada en el cual se toma en consideraci6n el efecto de difusión es el siguiente: [Formula Matemática].

  18. Puente pretensado sobre el Guadarrama. Villalba

    Directory of Open Access Journals (Sweden)

    Páez, A.

    1958-12-01

    Full Text Available En este artículo se describe y comenta la solución dada al puente de hormigón pretensado sobre el río Guadarrama, primero de los construidos mediante dovelas prefabricadas y solidarizadas después, mediante el pretensado de la armadura longitudinal.

  19. Sobre o natural e o actor

    OpenAIRE

    Tavares, Margarida

    2010-01-01

    Neste artigo, procura-se reflectir sobre o conceito de natural quando aplicado ao trabalho do actor. Parte-se de quatro relevantes textos da dramaturgia ocidental, a saber: Hamlet, de Shakespeare; Crítica da ‘Escola das mulheres’ e O improviso de Versalhes, de Molière; e O teatro cómico, de Goldoni.

  20. Comparisons of fission track age-determination and radioactivation analysis among radiation fields. Characteristic values for pneumatic tube, JRR-3M PN2

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Tatsuro [Kagoshima Univ. (Japan). Faculty of Education; Tomura, Kenji

    1996-01-01

    It is necessary for Fission track age determination and radioactivation analysis to define the energy spectrum of a reactor neutron as the basis for calculating the nuclear reaction rate. This study was made aiming to define the spectrum for PN2 pneumatic tube of No. 3 plant of Japan Atomic Energy Research Institute (JAERI). Characteristics such as conventional flux, cross reaction, neutron temperature and integral fast flux were examined for 3 facilities; JRR-2, JRR-4 and JRR-3M. And the neutron spectrum for each facility was estimated based on the assumptions; Maxwell distribution for thermal neutrons, 1/E for intermediate neutrons and Watt`s formula for fast neutrons. The present results showed that the spectrum for JRR-3M, PN2 was discontinuous in the range from the intermediate to the fast neutron, whereas those for other facilities were found considerably improved. (M.N.)

  1. Behaviour of the radiation of the suprathermal electrons at the Uragan-3M torsatron after rf heating off from ECE measurements

    International Nuclear Information System (INIS)

    The microwave radiometry is a well-known diagnostics to obtain the information on temporal evolution and radial profile of the electron temperature at U-3M torsatron plasma experiments. However, under low plasma density with this diagnostics we report on the large production of runaway electrons after RF heating pulse off. We notice a gradually increasing of the radiometer signal at the frequencies that match the second and third harmonics of electron cyclotron emission of the extraordinary mode. This effect could be explained with the existence of the ''runaway'' electrons in U-3M discharge. A phenomenological description of this process is presented, where the time evolution of the ECE radiation signal is compared to the electron density evolution

  2. Feasibility of CDP seismic reflection to image structures in a 200-m deep, 3-m thick coal zone near Palau, Coahuila, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Miller, R.D.; Saenz, V.; Huggins, R.J. (Kansas University, Lawrence, KS (USA). Kansas Geological Survey)

    1992-10-01

    The common-depth-point (CDP) seismic-reflection method was used to delineate subsurface structure in a 3-m thick, 220-m deep coal zone in the Palau area of Coahuila, Mexico. An extensive series of walkaway-noise tests was performed to optimize recording parameters and equipment. Reflection events can be interpreted from depths of approximately 100 to 300 m on CDP stacked seismic sections. The seismic data allow accurate identification of the horizontal location of the structure responsible for a drill-discovered 3-m difference in coal-zone depth between boreholes 150m apart. The reflection method can discriminate folding with wavelengths in excess of 20 m and faulting with offset greater than 2 m at this site.

  3. Temporal information needs in ResPubliQA: an attempt to improve accuracy. The UC3M Participation at CLEF 2010

    OpenAIRE

    Vicente-Díez, María Teresa; Moreno Schneider, Julián; Paloma MARTÍNEZ

    2010-01-01

    The UC3M team participates in 2010 in the second ResPubliQA evaluation campaign taking part in the monolingual Spanish task. On this occasion we have completely redesigned our Question Answering system, product of multiple efforts while being part of the MIRACLE team, by creating a whole new architecture. The aim was to gain in modularity, flexibility and evaluation capabilities that previous versions left pending. Despite its initial open-domain philosophy, the new system was tes...

  4. Analýza obchodních a marketingových aktivit společnosti 3M

    OpenAIRE

    Stašová, Jana

    2010-01-01

    The subject of this diploma thesis is besides the general introduction of the 3M Company and the B2B orientation which becomes more and more important nowadays also the practical part in form of situation analysis of the Automotive Aftermarket Division (AAD) as well as its marketing mix. The target market conditions, customer and competitive environment much like available human resources are important factors having influence on the components of the 4P concept. The objective of the thesis i...

  5. Anticancer Effect of a Novel Proteasome Inhibitor, YSY01A, via G2/M Arrest in PC-3M Cells in vitro and in vivo.

    Science.gov (United States)

    Zhang, Mei; Yuan, Xia; Xu, Bo; Guo, Wei; Ran, Fu-Xiang; Li, Run-Tao; Cui, Jing-Rong

    2015-01-01

    YSY01A is a new tripeptideboronic acid and an analog of PS341. However, YSY01A's antitumor effects and mechanism have not yet been elucidated. This study demonstrates that YSY01A inhibited proteasome activity by combining with the chymotrypsin-like (CT-L) site (β5i/β5), the post-glutamyl peptide hydrolase (PGPH) site (β1i/β1) and the trypsin-like (T-L) site (β2i/β2) in special fluorgonic substrates and proteasome probe tests. We explored the anticancer effect using methyl thiazolyltetrazolium (MTT) or sulforhodamine B (SRB), and PC-3M cells were sensitive to YSY01A among the four cancer cell types tested. The YSY01A antiproliferative effect was stronger than that of PS341. In vivo, YSY01A (1.25, 2.25, and 3.25 mg/kg) inhibited PC-3M cell xenograft tumor growth, and the tumor volume inhibition rate was approximately 40% to 60%. YSY01A arrested PC-3M cells in the G2/M phase of the cell cycle by flow cytometry (FCM). Many proteins related to the cell cycle were analyzed using western blot, and YSY01A was shown to increase p21, p27, cyclinB1, P-cdc2 (tyr15) and wee1 protein expression in both cells and tumor tissue in a concentration-dependent manner. YSY01A, a proteasome inhibitor, exerts anticancer effects on PC-3M cells in vitro and in vivo. The mechanism of the YSY01A-mediated antitumor effect is that the cell cycle is arrested at the G2/M stage. This study suggests that YSY01A may be a novel therapeutic agent for prostate cancer. PMID:26185531

  6. Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.

    Science.gov (United States)

    Bubier, Jason A; Jay, Jeremy J; Baker, Christopher L; Bergeson, Susan E; Ohno, Hiroshi; Metten, Pamela; Crabbe, John C; Chesler, Elissa J

    2014-08-01

    Extensive genetic and genomic studies of the relationship between alcohol drinking preference and withdrawal severity have been performed using animal models. Data from multiple such publications and public data resources have been incorporated in the GeneWeaver database with >60,000 gene sets including 285 alcohol withdrawal and preference-related gene sets. Among these are evidence for positional candidates regulating these behaviors in overlapping quantitative trait loci (QTL) mapped in distinct mouse populations. Combinatorial integration of functional genomics experimental results revealed a single QTL positional candidate gene in one of the loci common to both preference and withdrawal. Functional validation studies in Ap3m2 knockout mice confirmed these relationships. Genetic validation involves confirming the existence of segregating polymorphisms that could account for the phenotypic effect. By exploiting recent advances in mouse genotyping, sequence, epigenetics, and phylogeny resources, we confirmed that Ap3m2 resides in an appropriately segregating genomic region. We have demonstrated genetic and alcohol-induced regulation of Ap3m2 expression. Although sequence analysis revealed no polymorphisms in the Ap3m2-coding region that could account for all phenotypic differences, there are several upstream SNPs that could. We have identified one of these to be an H3K4me3 site that exhibits strain differences in methylation. Thus, by making cross-species functional genomics readily computable we identified a common QTL candidate for two related bio-behavioral processes via functional evidence and demonstrate sufficiency of the genetic locus as a source of variation underlying two traits.

  7. c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells.

    OpenAIRE

    Ming, X F; Kaiser, M.; Moroni, C

    1998-01-01

    Whereas signalling pathways involved in transcriptional control have been studied extensively, the pathways regulating mRNA turnover remain poorly understood. We are interested in the role of mRNA stability in cell activation and oncogenesis using PB-3c mast cells as a model system. In these cells the short-lived interleukin-3 (IL-3) mRNA is stabilized by ionomycin treatment and following oncogenesis. To identify the signalling pathways involved in these mechanisms, we analysed the effect of ...

  8. Measurement of the radiative L3-M vacancy transfer probabilities of some 4f elements and compounds using Indus-2 synchrotron radiation

    Science.gov (United States)

    Krishnananda; Mirji, Santosh; Badiger, N. M.; Tiwari, M. K.

    2016-08-01

    The L X-ray intensity ratios (ILα/ILl, ILα/ILβ, ILα/ILγ) and the radiative L3-M vacancy transfer probabilities (ηL3-M) of some 4f elements such as Gd, Tb, Ho and compounds; Pr2O3, Pr2(CO3)3·8H2O, Nd2O3, Sm2O3, Sm2(CO3)3·2.85H2O, Sm2(SO4)3·8H2O, Gd2(CO3)3, Tb2O3, Dy2(SO4)3, Ho2O3 and HoF3 have been measured using Indus-2 synchrotron radiation. The elements and compounds are excited by synchrotron radiation and the emitted characteristic L X-ray photons are measured with high resolution silicon drift detector. The measured intensity ratios of compounds are not influenced by the chemical environment. However, the ηL3-M values of compound targets indicate the effect of crystal structure.

  9. Room temperature syntheses and thermal behaviors of hydrogarnets Sr{sub 3}M{sub 2}(OH){sub 12} (M = Al, Cr and Fe)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yun-Feng [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Yang, Zhi, E-mail: kmyangz@hotmail.com [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Li, Yong-Ming; Guo, Jing [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Fu, Wen-Fu, E-mail: fuwf@mail.ipc.ac.cn [College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500 (China); Wang, Ying-Xia; Liao, Fu-Hui [College of Chemistry and Molecular Engineering, Peking University, Beijing 100871 (China); Li, Jianye [University of Wisconsin-Madison, Madison, WI 53706 (United States)

    2015-07-15

    Highlights: • All starting materials were common metal inorganic salts. • Hydrogarnets were synthesized by solid state reaction at room temperature. • The novel synthesis method has an advantage of quick reaction and easy operation. • As-synthesized hydrogarnets have different morphologies. - Abstract: Hydrogarnets Sr{sub 3}M{sub 2}(OH){sub 12} (M = Al, Cr and Fe) were synthesized through a solid state reaction at room temperature with Al(NO{sub 3}){sub 3}·9H{sub 2}O, CrCl{sub 3}·6H{sub 2}O, FeCl{sub 3}·6H{sub 2}O, Sr(NO{sub 3}){sub 2} and NaOH as the starting materials. All X-ray diffraction (XRD) data of Sr{sub 3}M{sub 2}(OH){sub 12} were indexed by the cubic system with the space group of Ia{sup −}3d. XRD, differential thermal analysis and thermogravimetric (DTA–TG), and scanning electron microscopy (SEM) were employed to investigate the structural stability, thermal properties and morphologies of Sr based hydrogarnets. The cause of room temperature synthesis and the thermal decomposition behaviors of Sr-based hydrogarnets Sr{sub 3}M{sub 2}(OH){sub 12} (M = Al, Cr and Fe) are discussed.

  10. Comparison of Sarns 3M heparin bonded to Duraflo II and control circuits in a porcine model: macro- and microanalysis of thrombi accumulation in circuit arterial filters.

    Science.gov (United States)

    Larson, D F; Arzouman, D; Kleinert, L; Patula, V; Williams, S

    2000-01-01

    Heparin-bonded perfusion circuits have been reported to reduce the thrombus formation during various levels of systemic heparinization. The goal of this study was to compare the efficacy of thrombo-resistance of the Sarns 3M heparin-bonded circuit to Baxter Duraflo II and untreated control in a porcine model. Fifteen Yorkshire pigs (60-65 kg) were anesthetized, heparinized with 3000 IU, intravenously (i.v.) and surgically cannulated with an internal jugular outflow and a femoral vein inflow. All circuits consisted of a 22-Fr venous cannula, centrifugal pump, arterial filter, an 18-Fr cannula for return and connected with equal lengths of 3/8" polyvinyl chloride tubing. The flows were maintained at 2.0 l/min for 4 h. Thrombus formation in filter samples were morphometrically analyzed through macro-densitometry, light microscopy, and scanning electron microscopy (SEM). Our findings revealed that the 3M circuit had significantly less gross thrombus (p < 0.001), 66% and 84% less microscopic thrombi and fivefold less SEM-measured aggregates (p = 0.03) compared to the Duraflo II and uncoated groups. This study demonstrated that the 3M heparin-bonded circuit had significantly reduced the formation of micro- and macro-thrombi in the minimally heparinized pig model compared to the Duraflo II and untreated control circuits.

  11. Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic lupus erythematosus.

    Science.gov (United States)

    Xiang, Nan; Li, Xiang-Pei; Li, Xiao-Mei; Wang, Guo-Sheng; Tao, Jin-Hui; Pan, Hai-Feng; Fang, Xuan; Ma, Qian; Yu, Ning

    2014-11-01

    Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with complex genetic predisposing factors involved. Ets-1 transcription factor plays an important role in the suppressive activity of CD4(+)CD25(+) Treg cells and stable expression of FOXP3. To find its potential role in the pathogenesis of SLE, we investigate the mRNA expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25(+) Treg cells from patients with SLE. Real-time transcription-polymerase chain reaction analysis was used to determine the expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25(+) Treg cells from 36 patients with SLE and 18 sex-and-age-matched healthy controls. The Ets-1 mRNA expression level was decreased in patients with SLE [0.225 (0.135, 0.337)] than healthy controls [0.528 (0.303, 0.681)] (P Ets-1 and FOXP3 expression was also found in new-onset SLE subgroup when compared with healthy controls (P Ets-1 and FOXP3 mRNA was not significantly different in hyperactive and lower active SLE group when compared with inactive SLE group, respectively (P > 0.05). There were no significant differences between SLE with lupus nephritis (LN) and SLE without LN either (P > 0.05). Associations of Ets-1 and FOXP3 mRNA expression levels with major clinical and laboratory parameters of SLE patients were also analyzed. However, no significant association was found. Significant positive correlation was found between Ets-1 and FOXP3 mRNA expression in CD4(+)CD25(+) Treg cells from SLE patients (r = 0.698, P Ets-1 mRNA were decreased in SLE patients and Ets-1 expression was positively correlated with the expression of FOXP3. It indicated that Ets-1 may play an important role in the stable expression of FOXP3 in CD4(+)CD25(+) Treg cells.

  12. Expression of CYP2A3 mRNA and its regulation by 3-methylcholanthrene, pyrazole, and ß-ionone in rat tissues

    Directory of Open Access Journals (Sweden)

    A.B. Robottom-Ferreira

    2003-07-01

    Full Text Available Cytochrome P450 (CYP 2A enzymes are involved in the metabolism of numerous drugs and hormones and activate different carcinogens. Human CYP2A6, mouse CYP2A5 and rat CYP2A3 are orthologous enzymes that present high similarity in their amino acid sequence and share substrate specificities. However, different from the human and mouse enzyme, CYP2A3 is not expressed in the rat liver. There are limited data about expression of CYP2A3 in extrahepatic tissues and its regulation by typical CYP inducers. Therefore, the objective of the present study was to analyze CYP2A3 mRNA expression in different rat tissues by RT-PCR, and to study the influence of 3-methylcholanthrene, pyrazole and ß-ionone treatment on its expression. Male Wistar rats were divided into four groups of 5 rats each, and were treated ip for 4 days with 3-methylcholanthrene (25 mg/kg body weight, pyrazole (150 mg/kg body weight, ß-ionone (1 g/kg body weight, or vehicle. Total RNA was extracted from tissues and CYP2A3 mRNA levels were analyzed by semiquantitative RT-PCR. CYP2A3 mRNA was constitutively expressed in the esophagus, lung and nasal epithelium, but not along the intestine, liver, or kidney. CYP2A3 mRNA levels were increased in the esophagus by treatment with 3-methylcholanthrene and pyrazole (17- and 7-fold, respectively, in lung by pyrazole and ß-ionone (3- and 4-fold, respectively, although not statistically significant, in the distal part of the intestine and kidney by 3-methylcholanthrene and pyrazole, and in the proximal part of the intestine by pyrazole. CYP2A3 mRNA was not induced in nasal epithelium, liver or in the middle part of the intestine. These data show that, in the rat, CYP2A3 is constitutively expressed in several extrahepatic tissues and its regulation occurs through a complex mechanism that is essentially tissue specific.

  13. 前列腺癌患者手术前后外周血调节性T细胞和FOXP3mRNA的表达及临床意义%Levels of CD4+CD25+Regulatory T Cells & Expression of FOXP3 mRNA after Operation in Peripheral Blood from Patients with Prostate Cancer and its Clinical Significance

    Institute of Scientific and Technical Information of China (English)

    章更生

    2011-01-01

    目的 探讨前列腺癌(Pca)患者手术前后外周血CD4+CD25+调节性T细胞(Tregs)及其特异标志物FOXP3mRNA的表达比例的变化及临床意义.方法 应用流式细胞术检测50例前列腺癌及50例正常对照组外周血单个核细胞(PBMC)中Tregs占CD4+T细胞的比例,应用RT-PCR技术检测人外周血PBMC FOXP3 mRNA的表达.结果 随着Gleason分级升高,CD4+CD25+Tregs/CD4+T比值和FOXP3 mRNA表达量均有升高趋势;Pca患者术前CD4+CD25+ Treg细胞占CD4+T细胞的比例和FOXP3 mRNA表达水平高于正常对照组(均P<0.05),术后水平与正常对照组差异无统计学意义;Pca组Tregs表达率与FOXP3 mRNA呈正相关(r=0.623,P<0.01).结论 Tregs及其特异标志物FOXP3具有维持自身免疫稳定和抑制肿瘤免疫作用,可能参与前列腺癌的发生.%Objective To explore the rate change of CD4+ CD25+ regulatory T cells and expression of F0XP3 mRNA after operation in peripheral blood from patients with prostate cancer and its clinical significance. Methods Flow cytometry was used to analyze the proportion of CD4+CD25+ regulatory T cells/CD4T cells in peripheral blood mononuclear cells (PBMC) among 50 patients with prostate cancer and 50 healthy controls. The expression of FOXP3 mRNA in PBMC was detected by RT-PCR. Results The value of CD4+CU25+Tregs/CD4+ T cells and expression of FOXP3 mRNA were increased with Gleason pathological parameters increased. And the value of CD4+CD25+ regulatory T cells/CD4+T cells and expression of FOXP3 mRNA in PBMC from patients with prostate cancer before operation were significantly higher than that of the healthy controls. But there were no statistical significance between patients with prostate cancer after operation and healthy controls. Correlative analysis showed that there was a positive correlation between the CD4+CD25+ regulatory T cells and the expression of F0XP3 mRNA in PBMC of the patients with prostate cancer (r=0.623,p<0.01). Conclusion CD4+CD25

  14. Observaciones sobre didáctica

    Directory of Open Access Journals (Sweden)

    Alfonso Tamayo Valencia

    2014-02-01

    Full Text Available  En el presente artículo, a partir de la conceptualización sobre didáctica y enseñanza, se plantean sus posibilidades en la educación superior, especialmente cuando reflexionamos en las prácticas de enseñanza desde un saber hacer que supere el hacer de esquemas tácitos y espontáneos que caracteriza en buena parte docencia universitaria. Desde esta perspectiva se aboga por la renovación de la concepción de la didáctica desde una postura epistemológica y psicológica sobre la manera como se construye el conocimiento.

  15. Consideraciones sobre la motricidad del violinista

    OpenAIRE

    Allende, Pablo

    2009-01-01

    Comienza la exposición hablando de que intenta prevenir las patologías en los violinistas mediante secuencias de ejercicios específicos, de diferentes técnicas corporales y fisioterapéuticas. Presenta datos estadísticos sobre el índice de patologías que se encuentran entre estos intérpretes para por último presentar tablas de ejercicios propiamente dichas para intentar paliar estas dolencias

  16. Productos derivados sobre bienes de consumo

    OpenAIRE

    Francisco Venegas Martinez; Salvador Cruz Ake

    2010-01-01

    Este trabajo de investigacion desarrolla un modelo de equilibrio general con expectativas racionales en tiempo continuo util para la determinacion de precios de contratos forward, contratos futuros, bonos cupon cero y opciones europeas (de compra y venta) sobre bienes de consumo. Para ello, el modelo considera un individuo representativo en una economia con dos bienes, los cuales son producidos con tecnologias estocasticas. Por ultimo, el modelo propuesto permite examinar estrategias para obt...

  17. Reflexiones sobre el concepto de justicia

    Directory of Open Access Journals (Sweden)

    Víctor C. Pascual Planchuelo

    2005-06-01

    Full Text Available Este ensayo constituye una reflexión sobre el concepto de Justicia. No se centra, como tantos estudios al respecto, en el plano teórico y metafísico, sino que atiende problemas de mayor actualidad: la opinión de los ciudadanos, la postura de los profesionales y otros asuntos controvertidos del ámbito del Derecho.

  18. Neopolares de problemas de empaquetamiento sobre semigrupos

    OpenAIRE

    Aráoz Durand, Julián Arturo

    1982-01-01

    Los neopolares permiten caracterizar las caras de un poliedro combinatorio como vértices de poliedros altamente estructurados. Esto sirve para generar planos de cortes y para obtener propiedades duales en problemas de programación entera. Gomory caracterizó neopolares para problemas sobre grupos, Aráoz en "Polyhedral Neopolarities" extendió estos resultados a semigrupos de cubrimiento. En este trabajo se caracterizan neopolares importantes de semigrupos de empaquetamiento que incluyen los pro...

  19. 3M纸片法在水质检验工作中的应用%Applications 3M Method in Water Quality Testing Work

    Institute of Scientific and Technical Information of China (English)

    吴波

    2015-01-01

    Objective To investigate the value of 3M method in water quality testing work. Methods Comparison of two methods to take random samples of the area of tap water, the second pressurized water samples and a total of 54 well water samples and water quality testing plate count method were used to detect disk diffusion method 3M Petrifilm (3M paper method). the total number of bacterial strains and testing standards in water samples. Results There were detected the presence of E. coli and Staphylococcus aureus significant differences were statistically significant (P<0.05). 3M method to detect the use of tap water samples, the second pressurized water sample and the average number of colonies well water sample was (32.7±8.31), the average number of colonies in plate count assay was (22.9±2.58) months, the two groups 54 parts of water samples to detect the average number of colonies was statistically significant difference (P<0.05). Conclusion Accurate conclusions 3M method to detect water quality, specificity, convenient, has application value.%目的:探讨3M纸片法在水质检验工作中的应用价值。方法随机采取该辖区内末梢水样品、二次加压水样品和井水样品共54份,分别采用3M Petrifilm检测纸片法(3M纸片法)和平皿计数法进行水质检验,比较两种方法检测标准菌株和水样中的细菌总数。结果比较两组方法检测大肠杆菌和金黄色葡萄球菌的结果,差异有统计学意义(P<0.05)。采用3M纸片法检测末梢水样品、二次加压水样品和井水样品的平均菌落数为(32.7±8.31)个,平皿计数法检测的平均菌落数为(22.9±2.58)个,两组方法检测54份水样品平均菌落数比较,差异有统计学意义(P<0.05)。结论3M纸片法检测水质的准确度高、特异性强,方便快捷,具有推广应用价值。

  20. Enseñanza sin puertas. La UC3M lanza una Convocatoria de Cursos Masivos Abiertos para profesores y departamentos

    OpenAIRE

    Santiuste Romero, Carlos; Delgado Kloos, Carlos

    2014-01-01

    La universidad se ha adherido a la plataforma edX, creada por el MIT y la Universidad de Harvard, y que reúne a prestigiosas universidades de todo el mundo. Y acaba de lanzar una convocatoria para que profesores y departamentos puedan presentar propuestas de cursos MOOCs (cursos masivos abiertos en línea, Massive Open Online Courses) para la plataforma edX. La UC3M pretende lanzar cuatro MOOCs en enero de 2015 y añadir posteriores cursos en sucesivas convocatorias. Contine: La...

  1. Influence of chisel width on shear bond strength of composite to enamel = Influência da largura do cinzel sobre a resistência ao cisalhamento da união esmalte/resina composta

    OpenAIRE

    Oliveira, Antônio Carlos Castellan de

    2009-01-01

    Objetivo: Avaliar a influência de diferentes larguras de cinzel sobre a resistência de união ao cisalhamento na interface esmalte dental/resina composta. Metodologia: As coroas de 60 dentes incisivos bovinos foram incluídas em resina acrílica e as superfícies vestibulares de esmalte foram planificadas e condicionadas com ácido fosfórico a 35 %. O sistema adesivo Single Bond (3M/ESPE) e de resina composta Z-250 (3M/ESPE) foram utilizados para fabricar restaurações cilíndricas de resina compost...

  2. 寻常型银屑病患者外周血单个核细胞SOCS-1、SOCS-3 mRNA的表达%The expression of SOCS-1 and SOCS-3 mRNA in patients with psoriasis vulgaris

    Institute of Scientific and Technical Information of China (English)

    郭红卫; 王京滨; 李国明; 李顺凡; 吴志华

    2007-01-01

    目的: 检测细胞因子信号抑制因子SOCS-1、SOCS-3 mRNA在寻常型银屑病患者外周血单个核细胞(PBMC)中的表达.方法: 从20例银屑病患者及20例健康志愿者外周血中分离PBMC,提取RNA,应用逆转录-聚合酶链反应(RT-PCR)方法检测SOCS-1、SOCS-3 mRNA的表达.结果: SOCS-1、SOCS-3 mRNA在银屑病患者中表达,在正常人中无表达,活动期银屑病患者较静止期患者SOCS-1、SOCS-3 mRNA表达增高.结论: SOCS-1、SOCS-3可能在银屑病的Th1免疫反应中发挥作用.

  3. The expression of DcR3 mRNA in peripheral blood mononuclear cells from patients with Guillain-Barré syndrome%吉兰-巴雷综合征外周血单个核细胞DcR3mRNA表达

    Institute of Scientific and Technical Information of China (English)

    陆嘉茵; 李静; 朱太卿; 田发发; 杨欢; 陈毓茜

    2011-01-01

    Objective To investigate the expression of DcR3 mRNA in peripheral blood mononuclear cells (PBMCs) from patients with Guillain-Barré syndrome (GBS).And to discuss the correlation among cerebrospinal fluid (CSF) -Ig, the severity of GBS and DcR3 mRNA.Methods Thirty-six patients with GBS and 20 healthy controls were included.The expression of DcR3 mRNA in PBMCs was detected by reverse transcription-polymerase chain reaction (RT-PCR).The correlation between the severity of GBS and the expression of DcR3 mRNA was analyzed.The CSF level of CSF-Ig was also analyzed.Results DcR3 mRNA level in GBS patients (0.40 ± 0.08) was significantly higher than in the healthy control (0.17 ± 0.04) (P<0.01).The expression of DcR3 mRNA was comparable between the mild group (0.39 ±0.07) and the severe group (0.41±0.05) (P>0.05).The level of CSF-Ig was also comparable between the mild group [IgG (0.l23 ±0.113) g/L, IgA (0.016± 0.012) g/L, IgM (0.012 ±0.011) g/L]and the severe group [IgG (0.128 ±0.112) g/L, IgA (0.015 ± 0.011) g/L, IgM (0.013±0.013) g/L](P>0.05).There was no correlation between the levels of CSF-Ig and DcR3 mRNA (rIgG = 0.0083, rIgA = 0.0056, rIgM = 0.0015, P> 0.05).Conclusions The expression of DcR3 mRNA in PBMCs increased significantly in GBS patients, indicating that DcR3 could be involved in the pathogenesis of GBS.There was no correlation between GBS severity and DcR3 mRNA level or between CSF-Ig and DcR3 mRNA levels.%目的 研究吉兰-巴雷综合征(Guillain-Barré syndrome,GBS)患者外周血单个核细胞(PBMCs)中凋亡相关基因诱骗受体(DCR3)mRNA的表达水平.探讨DcR3与GBS疾病严重程度及脑脊液免疫球蛋白(CSFIg,包括IgG、IgA、IgM)水平之间的关联性.方法 以36例GBS患者和20名健康人为研究对象,应用反转录聚合酶链反应(RT-PCR)检测外周静脉血PBMCs DcR3 mRNA表达水平,并对GBS患者CSF-Ig水平与疾病严重程度和DcR3 mRNA表达的相关性进行分析.结果 GBS

  4. Expressions of T-bet, GATA-3, RORγt and FoxP3 mRNA in peripheral blood of patients with allergic asthma%过敏性哮喘患者外周血T-bet、GATA-3、RORγt和FoxP3 mRNA的表达变化

    Institute of Scientific and Technical Information of China (English)

    施宇衡; 时国朝; 马佳韵; 艾香艳; 朱海星; 万欢英

    2011-01-01

    Objective To investigate the expressions of T-bet, GA TA-3, RORγt and FoxP3 mRNA in peripheral blood of patients with allergic asthma. Methods Seventeen patients with mild persistent and 13 patients with moderate-severe persistent house dust mite allergic asthma and 14 healthy controls were enrolled in this study.Expressions of T-bet,GATA-3,RORγt and FoxP3 mRNA in peripheral blood mononuclear cell (PBMC) were determined by quantitative fluorescence PCR. Results Expression of GATA-3 mRNA in mild and moderate-severe asthma patients was significantly higher than that in normal controls (P<0.01). Furthermore, expression of RORγt mRNA in patients with moderate-severe asthma was significantly higher than that in mild asthma patients and normal controls (P<0.01). However, there was no difference in expressions of T-bet and FoxP3 mRNA among these three groups (P>0.05). Conclusions GATA-3 expression was increased in allergic asthma,and RORγt expression was increased in moderate-severe allergic asthma. GA TA-3 and RORγt may play important role in the pathogenesis of allergic asthma.%目的:探讨特异性转录因子T-bet、GATA-3、RORγt和FoxP3 mRNA在过敏性哮喘患者外周血中的表达变化.方法:选择30例慢性持续期的屋尘螨过敏性哮喘患者,其中轻度哮喘17例、中重度哮喘13例,14名正常人作为对照.通过荧光实时定量PCR方法检测3组患者外周血单个核细胞(PBMC)中T-bet、GATA-3、RORγt和FoxP3mRNA的表达.结果:轻度和中重度哮喘患者的GATA-3 mRNA表达均显著高于正常人(均P0.05).结论:过敏性哮喘中GATA-3表达增加,中重度哮喘中RORγt表达增加,GATA-3和RORγt在哮喘发病中起着重要的作用.

  5. Expression and significance of T - bet mRNA and GATA3 mRNA of preeclampsia patients' decidua basalis%T-bet mRNA和GATA3 mRNA在子痫前期蜕膜组织中的表达

    Institute of Scientific and Technical Information of China (English)

    田晓瑜; 杨海澜; 何银芳

    2012-01-01

    Objective: To investigate the different expression of various in decidua basalis between preeclampsia and normal pregnant women. Methods; The patients with preeclampsia and normot ensive of late pregnancy were selected as study group and control group. The levels of T - bet mRNA and GATA3 mRNA in both group were measured by RT - PCR. Results: ①The levels of T - bet mRNA were significant differences between severe preeclampsia group and normal pregnancy group, severe preeclampsia group and mild preeclampsia group (P <0.01, P <0.01 ). There was no significantly statistical difference between mild preeclampsia group and normal pregnancy group (P = 0. 089). ②The levels of GATA3 mRNA were significant differences between severe preeclampsia group and normal pregnancy group, severe preeclampsia group and Mild preeclampsia group (P < 0.01, P < 0.01). There was no significantly statistical difference between mild preeclampsia group and normal pregnancy group (P = 0.127). ③The ratio of T - bet mRNA and GATA3 mRNA were differerces between severe preeclampsia group and normal pregnancy group, severe preeclampsia group and mild preeclampsia group (P < 0.01, P < 0.01). The difference of The ratio of T - bet mRNA and GATA3 mRNA among mild preeclampsia group and normal pregnancy group were no statistically significant (P = 0. 322). Conclusions: The disbalant expression levels of T - bet mRNA and GATA - 3 mRNA may be lead to the shift of Th1 in preeclampsia.%目的 探讨T - bet mRNA和GATA3 mRNA在正常妊娠产妇及子痫前期患者蜕膜组织中的表达差异.方法 选取子痫前期和正常妊娠产妇作为实验组和对照组,采用RT - PCR方法,检测各组产妇蜕膜组织中T- bet mRNA和GA-TA3mRNA表达水平.结果 ①子痫前期重度组与轻度组相比,子痫前期重度组与正常组相比T- bet mRNA表达量的差异有统计学意义(P<0.01,P<0.01).子痫前期轻度组与正常组T- bet mRNA表达量相比较差异无统计学意义(P=0

  6. The degree of leukocytosis and urine GATA-3 mRNA levels are risk factors for severe acute kidney injury in Puumala virus nephropathia epidemica.

    Directory of Open Access Journals (Sweden)

    Daniel H Libraty

    Full Text Available Puumala hantavirus (PUUV infection, also known as nephropathia epidemica, is the most common cause of hemorrhagic fever with renal syndrome (HFRS in Europe. The pathogenesis of PUUV nephropathia epidemica is complex and multifactorial, and the risk factors for severe acute kidney injury (AKI during acute PUUV infection are not well defined. We conducted a prospective study of hospitalized patients with PUUV infection in Tampere, Finland to identify acute illness risk factors for HFRS severity. Serial daily blood and urine samples were collected throughout acute illness and at 2 week and 6 month convalescent visits. By univariate analyses, the maximum white blood cell count during acute illness was a risk factor for severe AKI. There were no significant associations between PUUV-induced AKI severity and platelet counts, C-reactive protein, or alanine aminotransferase levels. Maximum plasma interleukin (IL-6, urine IL-6, and urine IL-8 concentrations were positively associated with PUUV-induced AKI. Finally, the maximum urinary sediment GATA-3 mRNA level was positively correlated with the peak fold-change in serum creatinine, regardless of AKI severity classification. By multivariate analyses, we found that the maximum levels of leukocytes and urinary sediment GATA-3 mRNA during acute illness were independent risk factors for severe PUUV-induced AKI. We have identified novel acute illness risk factors for severe PUUV-induced AKI.

  7. Exploring artificial layered heterostructures of LaM'O3/LaM''O3 (M'M''= NiCr, FeCr and NiV).

    Science.gov (United States)

    Liu, J.; Kareev, M.; Freeland, J. W.; Kareev, A.; Lee, H. N.; Chakhalian, J.

    2008-03-01

    Digital synthesis of atomically sharp interfaces between strongly correlated electron systems can provide a template to build completely new materials. Here we present our results on magnetism and electronic structure in LaM'O3/LaM''O3 (M'M''= NiCr, FeCr and NiV) superlattices by using polarized X-ray spectroscopies. Using laser MBE, the (111) and (100) oriented ultra-thin superlattices were grown with alternating layer thicknesses of 1 unit cell. In the bulk, LaMO3 (M=Cr,Fe,V) are antiferromagnetic insulators while LaNiO3 is a paramagnetic metal. The evolution of element specific magnetism and charge at the interface of LFO/LCO, LNO/LVO and LNO/LCO superlattices with temperature and an applied magnetic field will be discussed in detail. The superlattice results will be contrasted to the bulk magnetic properties of the constituent layers. The work has been supported by U.S. DOD-ARO under Contract No. 0402-17291.

  8. Y chromosome haplotype diversity in Mongolic-speaking populations and gene conversion at the duplicated STR DYS385a,b in haplogroup C3-M407.

    Science.gov (United States)

    Malyarchuk, Boris A; Derenko, Miroslava; Denisova, Galina; Woźniak, Marcin; Rogalla, Urszula; Dambueva, Irina; Grzybowski, Tomasz

    2016-06-01

    Y chromosome microsatellite (Y-STR) diversity has been studied in different Mongolic-speaking populations from South Siberia, Mongolia, North-East China and East Europe. The results obtained indicate that the Mongolic-speaking populations clustered into two groups, with one group including populations from eastern part of South Siberia and Central Asia (the Buryats, Barghuts and Khamnigans) and the other group including populations from western part of Central Asia and East Europe (the Mongols and Kalmyks). High frequency of haplogroup C3-M407 (>50%) is present in the Buryats, Barghuts and Khamnigans, whereas in the Mongols and Kalmyks its frequency is much lower. In addition, two allelic combinations in DYS385a,b loci of C3-M407 haplotypes have been observed: the combination 11,18 (as well as 11,17 and 11,19) is frequent in different Mongolic-speaking populations, but the 11,11 branch is present mainly in the Kalmyks and Mongols. Results of locus-specific sequencing suggest that the action of gene conversion is a more likely explanation for origin of homoallelic 11,11 combination. Moreover, analysis of median networks of Y-STR haplotypes demonstrates that at least two gene conversion events can be revealed-one of them has probably occurred among the Mongols, and the other event occurred in the Barghuts. These two events give an average gene conversion rate range of 0.24-7.1 × 10(-3) per generation. PMID:26911356

  9. New rock salt-related oxides Li{sub 3}M{sub 2}RuO{sub 6} (M=Co, Ni): Synthesis, structure, magnetism and electrochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Laha, S. [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012 (India); Morán, E., E-mail: emoran@quim.ucm.es [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Sáez-Puche, R.; Alario-Franco, M.Á.; Dos santos-Garcia, A.J. [Departamento de Químicas Inorganica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid (Spain); Gonzalo, E.; Kuhn, A.; García-Alvarado, F. [Universidad CEU San Pablo, Facultad de Farmacia, Departamento de Química, 28668 Boadilla del Monte, Madrid (Spain); Sivakumar, T.; Tamilarasan, S.; Natarajan, S.; Gopalakrishnan, J. [Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012 (India)

    2013-07-15

    We describe the synthesis, crystal structure, magnetic and electrochemical characterization of new rock salt-related oxides of formula, Li{sub 3}M{sub 2}RuO{sub 6} (M=Co, Ni). The M=Co oxide adopts the LiCoO{sub 2} (R-3m) structure, where sheets of LiO{sub 6} and (Co{sub 2}/Ru)O{sub 6} octahedra are alternately stacked along the c-direction. The M=Ni oxide also adopts a similar layered structure related to Li{sub 2}TiO{sub 3}, where partial mixing of Li and Ni/Ru atoms lowers the symmetry to monoclinic (C2/c). Magnetic susceptibility measurements reveal that in Li{sub 3}Co{sub 2}RuO{sub 6}, the oxidation states of transition metal ions are Co{sup 3+} (S=0), Co{sup 2+} (S=1/2) and Ru{sup 4+} (S=1), all of them in low-spin configuration and at 10 K, the material orders antiferromagnetically. Analogous Li{sub 3}Ni{sub 2}RuO{sub 6} presents a ferrimagnetic behavior with a Curie temperature of 100 K. The differences in the magnetic behavior have been explained in terms of differences in the crystal structure. Electrochemical studies correlate well with both magnetic properties and crystal structure. Li-transition metal intermixing may be at the origin of the more impeded oxidation of Li{sub 3}Ni{sub 2}RuO{sub 6} when compared to Li{sub 3}Co{sub 2}RuO{sub 6}. Interestingly high first charge capacities (between ca. 160 and 180 mAh g{sup −1}) corresponding to ca. 2/3 of theoretical capacity are reached albeit, in both cases, capacity retention and cyclability are not satisfactory enough to consider these materials as alternatives to LiCoO{sub 2}. - Graphical abstract: Two new rock salt related oxides of formula, Li{sub 3}M{sub 2}RuO{sub 6}, (M=Co, Ni) have been prepared. The M=Co oxide adopts the LiCoO{sub 2} (R-3m) structure and the M=Ni oxide adopts a similar layered structure related to Li{sub 2}TiO{sub 3,} monoclinic (C2/c), with partial mixing of Li and Ni/Ru atoms. For Li{sub 3}Co{sub 2}RuO{sub 6}, oxidation state for Ru is 4+ and antiferromagnetic (AFM) order is

  10. Comentario sobre levantar la mano sobre uno mismo, de jean améry

    OpenAIRE

    Pilar González Rivera

    2010-01-01

    Resumen En el libro de Jean Améry (seudónimo de Hans Mayer), Levantar la mano sobre uno mismo. Discurso sobre la muerte voluntaria, el autor utiliza argumentos de orden filosófico y suministra algunos escasos datos autobiográficos (como la aterradora experiencia sufrida por él al haber sido víctima de la persecución y tortura nazis en dos ocasiones, debido a su condición de hijo de padre judío) para justificar la “muerte voluntaria”, como llama al sui...

  11. ESTUDO SOBRE O IMPACTO DOS PROCESSADORES HOSPEDEIROS

    Directory of Open Access Journals (Sweden)

    Alba S. B. Lopes

    2008-05-01

    Full Text Available Arquiteturas reconfiguráveis são dispositivos de hardware capazes de modificar sua estrutura de hardware de acordo com a aplicação a ser executada. Tais dispositivos surgiram como uma alternativa às soluções de hardware tradicionais na tentativa de equilibrar flexibilidade e desempenho. Uma das principais formas de utilização de arquiteturas reconfiguráveis corresponde a um bloco reconfigurável anexado a um processador hospedeiro. Esse processador é responsável por executar diversas tarefas críticas, incluindo o particionamento hardware/software e indicar o momento do bloco reconfigurável executar. Apesar de existirem diversas propostas de arquiteturas reconfiguráveis na literatura, pouco se estudou sobre o impacto do processador hospedeiro na arquitetura. Nesse contexto, esse artigo apresenta um estudo sobre o impacto do processador hospedeiro no desempenho da arquitetura reconfigurável híbrida. Como estudo de caso foi realizada uma avaliação sobre o uso dos processadores SPARC V8 da Sun Microsystems e Nios II da Altera como processadores hospedeiros da arquitetura reconfigurável híbrida RoSA. O objetivo deste estudo é realizar a comparação entre o desempenho desses processadores e identificar qual deles é o mais adequado para anexar a arquitetura em questão. Os resultados mostraram que foi possível alcançar até 47% de ganho de desempenho com o uso do processador Nios II em comparação ao SPARC V8, indicando o primeiro como mais adequado para a arquitetura RoSA. PALAVRAS-CHAVE: arquiteturas reconfiguráveis, processador hospedeiro, desempenho.

  12. Literatura infantil sobre problemas infantiles: la diabetes

    OpenAIRE

    Lázaro Fernández, Patricia

    2015-01-01

    Debido al creciente número de casos de diabetes infantil que se está dando en la sociedad actual, no es raro encontrarse en las aulas cada vez más casos de esta enfermedad. Por esta razón, he decidido analizar dos libros sobre esta temática, para hacer un acercamiento del material seleccionado a las aulas y poder desarrollar junto con los niños un aprendizaje colectivo y cooperativo. En este trabajo se expone la importancia de la literatura y la literatura infantil como una ...

  13. Claves sobre el poder de las mujeres

    OpenAIRE

    García de León Álvarez, María Antonia

    2012-01-01

    El objeto de este texto es esbozar una síntesis sobre algunos nudos de mi obra en el área de Género y Poder. El estudio del poder es un punto de partida ineludible para abordar todo tema de Género, es decir, es necesario arrancar desde la comprensión del fenómeno social del poder, ya que el Patriarcado es un sistema estructurado de poder por género. Este punto de partida indica la relevancia del tema (nada más ni nada menos que el poder, tema clave en las Ciencias Sociales).

  14. Mapping sobre arquitecturas heterogéneas

    OpenAIRE

    De Giusti, Laura Cristina

    2008-01-01

    La programación de algoritmos paralelos, a diferencia de los algoritmos secuenciales, no cuenta para su representación con un único modelo. Esa carencia ocasiona que su aplicación sobre una arquitectura heterogénea, a través de modelos existentes, no halle el resultado que se ambiciona. La computación paralela ha propuesto, como pocas, significativos quiebres en el ámbito de la Ciencia de la Computación, al provocar la reformulación y generación de nuevos conceptos. El desarrollo de nuevos mo...

  15. Apuntes Sobre el Cultivo del Cacao.

    Directory of Open Access Journals (Sweden)

    Ochoa Horacio Ochoa

    1940-12-01

    Full Text Available En el presente artículo se hablara del proceso de fermentación del cacao, pero antes de entrar a detallar este proceso, es conveniente dar algunas anotaciones sobre los sistemas de recolección o “cosecha” empleados en distintos lugares, pues ellos tienen sus diferencias y en ocasiones no se efectúan con todo el cuidado necesario tanto para el árbol como para el producto que irá a los depósitos de fermentación.

  16. Futuros: estudo de caso sobre futuros cambiais

    OpenAIRE

    Santo, Paula Cristina Rosa da Silva Espírito

    2010-01-01

    Mestrado em Contabilidade A presente dissertação foi realizada com vista à obtenção do grau de mestre em Contabilidade pelo Instituto Superior de Contabilidade e Administração de Lisboa. Para o desenvolvimento desta dissertação foi escolhido o tema “Contratos de Futuros”. Em termos estruturais esta monografia divide-se em duas partes. Na primeira parte faz-se uma exposição sobre o tema os “Futuros”. Na segunda parte é apresentado o trabalho de investigação que foi desenvolvido. Na...

  17. Algunas reflexiones sobre la supervivencia empresarial

    OpenAIRE

    Sarabia Alzaga, José María

    1995-01-01

    Dos bloques-tópico, bien conocidos, configuran el esquema lógico de las reflexiones que se proponen. El primero de ellos se centra en nuestra realidad global: el entorno; el segundo, en los impactos que éste ha generado en la empresa, exponiendo una síntesis contrastada -y hoy día vigente- sobre cómo las empresas de éxito están consiguiendo sobrevivir. Como conclusión, se sintetizan algunas ideas o lineas generales de actuación que pudieran ayudar a mejorar o reforzar las propias experiencias...

  18. Sentencias Constitucionales sobre la muerte digna

    OpenAIRE

    Serrano, J. M.

    2006-01-01

    La sentencia comentada ha sido considerada como relevante en la discusión sobre el derecho a la vida en relación con la eutanasia. Sin embargo, las peculiaridades del caso qeu le dio origen y la propia argumentación del tribunal la alejan d euna interpretación relevante en torno a los dos tópicos del derecho a la vida y a la dignidad. Por el contrario la sentencia resulta decepcionate en su argumentación más propia. Primero respecto a la propia huelga de hambre que condena sin matices en rela...

  19. Consideraciones sobre de la ética

    OpenAIRE

    Enrique Cantolla Bernal

    2005-01-01

    El presente ensayo muestra como el hombre, a través de la historia, a estado constantemente buscando beneficios para su vida y ha debido cumplir con varias tareas, que con el tiempo han dado origen a costumbres y comportamientos que han llevado a constituir la moral y la ética. Esta última, nos permite definir y determinar los principales fines de la vida del hombre y cuales son los principios y normas que lo rigen. Así, el estudio de la ética nos plantea la interrogante sobre "los fines de l...

  20. Puntualizaciones sobre el concepto de latencia

    OpenAIRE

    Bortolazzo, Antonela

    2007-01-01

    El presente escrito revisa un concepto elaborado por Freud, como es la noción de Período de latencia sexual. Antes de hacer explícito el enfoque desde el cual será abordado quisiera mencionar que, lo que a continuación se desarrolla se enmarca en el trabajo de investigación que sobre el concepto de Latencia realiza, desde hace catorce años, la Cátedra de Psicología Evolutiva I, de la cual formo parte. En esta oportunidad me propongo indagar el concepto de latencia en el marco de la teoría ...

  1. Notas sobre envidia, equilibrio y optimalidad

    OpenAIRE

    Cristini, Marcela; Chisari, Omar Osvaldo

    1980-01-01

    Demostramos aquí -aún para coeficientes de producción distintos de la unidad- la suficiencia de las características del equilibrio para determinar el efecto aludido sobre la situación de ambos agentes. Damos otra condición suficiente, que no supone necesariamente el equilibrio; generalizamos los resultados a un número mayor de consumidores y deducimos propiedades del óptimo de Pareto, definido como aquella situación en la que no es posible mejorar el nivel de utilidad de un agente sin reducir...

  2. Efecto de masticar chicle sobre la halitosis

    OpenAIRE

    De Luca Monasterios, Fiorella; Chimenos Küstner, Eduardo; López López, José

    2014-01-01

    Fundamento y objetivo: Este estudio pretende estimar la prevalencia de halitosis oral en una población joven y mostrar el efecto del chicle sobre el aliento. Pacientes y método: Estudio prospectivo de campo descriptivo correlacional, de corte transversal. Se seleccionaron a conveniencia 121 jóvenes, de los que 98 concluyeron el estudio, el cual se realizó en el Hospital Odontológico Universitario-Universidad de Barcelona. El protocolo consistió en: cuestionario, evaluación clínica oral, prueb...

  3. El tullido. Un cuento sobre los cuentos

    OpenAIRE

    Fernández-Urtasun, R. (Rosa)

    2005-01-01

    Este artículo realiza una lectura literaria y simbólica de El tullido, uno de los cuentos de Christian Andersen que pasó desapercibido entre los relatos que se publicaron tras su muerte. El relato del argumento va acompañado de una reflexión sobre los temas que aparecen recogidos en el texto: las tradiciones orales, la belleza del arte, la esperanza, la creación, la importancia de la escritura y de la lectura, la esencia de la literatura.

  4. Ensayo sobre la melancolía

    Directory of Open Access Journals (Sweden)

    Marta Chacón Salinas

    2013-07-01

    Full Text Available Este trabajo es un intento de delimitar la melancolía del conjunto de los trastornos depresivos y de reflexionar sobre sus características tal como aparecen en el discurso de los melancólicos. Se consideran algunas hipótesis en la línea psicoanalítica freudiana y lacaniana (Lambottc, Kristeva para entender cómo se va constituyendo en sus características principales: la intolerancia a la pérdida del objeto y el desfallecimiento del símbolo que le impide elaborar este duelo.

  5. Recursos sobre propiedad intelectual en internet

    OpenAIRE

    Sorli Rojo, Ángela; Merlo Vega, José Antonio

    2001-01-01

    El concepto de propiedad intelectual, entendido en su sentido más amplio, englobaría todos los aspectos relacionados con los derechos que se obtienen de una creación, tanto en su forma original, como de sus posibles reproducciones y transformaciones. En este trabajo se recopilan y analizan una serie de fuentes de información accesibles en Internet sobre este tema. No obstante, la idea de propiedad intelectual no coincide plenamente con la de propiedad industrial, que es mucho m...

  6. Productos derivados sobre bienes de consumo

    OpenAIRE

    Francisco Venegas Martínez; Salvador Cruz Ake

    2010-01-01

    Este trabajo de investigación desarrolla un modelo de equilibrio general con expectativas racionales en tiempo continuo útil para la determinación de precios de contratos forward , contratos futuros, bonos cupón cero y opciones europeas (de compra y venta) sobre bienes de consumo. Para ello, el modelo considera un individuo representativo en una economía con dos bienes, los cuales son producidos con tecnologías estocásticas. Por último, el modelo propuesto permite examinar estrategias para o...

  7. Avances sobre bases de datos no convencionales

    OpenAIRE

    Arroyuelo, Jorge; Esquivel, Susana Cecilia; Grosso, Alejandro; Ludueña, Verónica; Reyes, Nora Susana; Chávez, Edgar; Navarro, Gonzalo

    2014-01-01

    En la actualidad han surgido, debido a los avances alcanzados en tecnologías de información y comunicación, aplicaciones no tradicionales sobre bases de datos de todo tipo de datos, valga la redundancia. Éstos pueden ser imágenes, texto libre, secuencias de ADN, audio, video, etc., pueden estar o no estructurados y provenir de diversas fuentes (satélites, telescopios, revistas, fotografías, música, etc.), como también ser de diferentes tamaños, generalmente muy grandes. Por otro lado, las con...

  8. Soportes apoyados sobre vigas pretensadas (EE. UU.

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1965-12-01

    Full Text Available This work has been awarded a prize by the Prestreesed Concrete Institute. It refers to a number of flyovers on the Arroyo Seco, of California. This river has been canalized, to help drainage in case of heavy rainfall. The canal runs through a highly populated zone, and a motor road and accessory ramps had to cross the canal. The resulting design involves three prestressed girders, lightly arched in a parabolic outline, resting on each river shore, running along the line of the bridge, over the canal. It was decided that the bridge piles should not rest on the river bed, in order not to reduce its flow capacity. The girders of a maximum length of 39 ms, are box shaped, and stiffened with thin diaphragms. The cylindrical pile, 1.50 m in diameter, is an integral part of the girder, and applies to it a concentrated load of about 4000 tons. The girders rest on reinforced concrete cubes, which in turn are supported by concrete slabs and piles driven into the soil.Esta obra ha sido premiada por el Prestressed Concrete Institute y se refiere a una serie de pasos superiores sobre el Arroyo Seco, en California, que se ha canalizado para servir de desagüe en el caso de avenidas torrenciales. El canal se halla en una zona de edificación densa y se trata del paso—sobre aquél—de una autopista y rampas de acceso. La solución adoptada consistió en tres vigas pretensadas, ligeramente arqueadas con perfil parabólico, apoyadas en las dos márgenes y situadas en correspondencia con los tres soportes, sobre el propio canal, ya que ninguno de aquéllos debía apoyarse en el lecho de este último al objeto de no disminuir su capacidad de desagüe. Las vigas—de unos 39 m de longitud la mayor—son del tipo cajón, rigidizadas con unos diafragmas de pequeño espesor. El soporte cilíndrico, de 1,50 m de diámetro, se solidariza con la viga y le transmite una notable carga concentrada, del orden de 4.000 toneladas. Los apoyos de estas vigas son simples dados

  9. Reflexiones sobre contabilidad privada y contabilidad nacional

    OpenAIRE

    José Arturo Gutiérrez

    1995-01-01

    Se discuten las interrelaciones de la contabilidad privada y la contabilidad nacional, insistiendo en sus condicionantes internos contradictorios en relación con la sobredeterminación de la formación económico-social vigente. En relación con ello se introduce la reflexión sobre la unidad contradictoria entre empresa y capital, esto es, la base técnica frente a su determinante socioeconómico, conflicto que la propia contabilidad privada expresa: al describir el capital aporta necesariamente el...

  10. 3M Petrifilm Staph Express Count plate method for the enumeration of Staphylococcus aureus in selected types of meat, seafood, and poultry: collaborative study.

    Science.gov (United States)

    McMahon, Wendy A; Aleo, Victoria A; Schultz, Ann M; Horter, Barbara L; Lindberg, Kathryn G

    2003-01-01

    The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Four foods--cooked, diced chicken; cured ham; smoked salmon; and pepperoni--were analyzed for S. aureus by 12 collaborating laboratories. For each food tested, the collaborators received 8 blind test samples consisting of a control sample, a low inoculation level, a medium inoculation level, and a medium inoculation level with background flora, each in duplicate. The mean log10 counts for the methods were comparable for all 4 foods. The repeatability and reproducibility variances of the 24 h Petrifilm Staph Express Count plate method were similar to those of the 72 h standard method.

  11. 3M Petrifilm Staph Express Count plate method for the enumeration of Staphylococcus aureus in selected types of processed and prepared foods: collaborative study.

    Science.gov (United States)

    Silbernagel, Karen M; Jechorek, Robert P; Carver, Charles N; Horter, Barbara L; Lindberg, Kathryn G

    2003-01-01

    The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Five foods--frozen lasagna, custard, frozen mixed vegetables, frozen hashbrowns, and frozen batter-coated mushrooms--were analyzed for S. aureus by 13 collaborating laboratories. For each food tested, the collaborators received 8 blind test samples consisting of a control sample, a low inoculation level, a medium inoculation level, and a medium inoculation level with background flora, each in duplicate. The mean log10 counts for the methods were comparable for all 5 foods. The repeatability and reproducibility variances of the 24 h Petrifilm Staph Express Count plate method were similar to those of the 72 h standard method.

  12. Synthesis and structure of new framework phosphates Li1/4M7/4(PO4)3(M = Nb, Ta)

    International Nuclear Information System (INIS)

    New lithium-niobium and lithium-tantalum phosphates Li1/4M7/4(PO4)3(M = Nb, Ta) are synthesized by the solid-phase method. The compounds prepared are characterized using electron microprobe analysis, X-ray powder diffraction, and IR spectroscopy. The crystal structure of the Li1/4Ta7/4(PO4)3 phosphate is determined from the X-ray powder diffraction data (the Rietveld method) and belongs to the framework type. The framework of the structure consists of TaO6 and LiO6 vertex-shared octahedra and PO4 tetrahedra. The isostructural phosphates Li1/4M7/4(PO4)3 crystallize in the trigonal crystal system (space group R3-barc, Z = 6) and belong to the NaZr2(PO4)3 structure type.

  13. Structural and electronic properties of ScnOm (n=1~3, m=1~2n) clusters: Theoretical study using screened hybrid density functional theory

    CERN Document Server

    Yang, Yu; Zhang, Ping; 10.1103/PhysRevB.84.205430

    2011-01-01

    The structural and electronic properties of small scandium oxide clusters ScnOm (n = 1 - 3, m = 1 - 2n) are systematically studied within the screened hybrid density functional theory. It is found that the ground states of these scandium oxide clusters can be obtained by the sequential oxidation of small "core" scandium clusters. The fragmentation analysis demonstrates that the ScO, Sc2O2, Sc2O3, Sc3O3, and Sc3O4 clusters are especially stable. Strong hybridizations between O-2p and Sc-3d orbitals are found to be the most significant character around the Fermi level. In comparison with standard density functional theory calculations, we find that the screened hybrid density functional theory can correct the wrong symmetries and yield more precise description for the localized 3d electronic states of scandium.

  14. Large magnetocaloric effect in La0.845Sr0.155Mn1-xMxO3 (M = Mn, Cu, Co) perovskites

    Science.gov (United States)

    Phan, Manh-Huong; Phan, The-Long; Yu, Seong-Cho; Tho, Nguyen Duc; Chau, Nguyen

    2004-06-01

    We present the results of an investigation on the magnetocaloric effect in the perovskites of La0.845Sr0.155Mn1-xMxO3 (M = Mn, Cu, Co). It is found that there was a large magnetic entropy change, i.e. a large magneto-caloric effect, in all these samples. Among them, the magnetic entropy change reaches a maximum value of 2.67 J/kg K at the applied field of 13.5 kOe for the Cu-doped sample, suggesting that this material would be a suitable candidate for the advanced magnetic refrigeration technology. The large magnetic entropy change produced by the abrupt reduction of magnetization is attributed to the strong coupling between spin and lattice that occurs in the vicinity of the ferromagnetic-paramagnetic transition temperature (TC) - which is experimentally verified by electron paramagnetic resonance study.

  15. Yellow phosphors doping with Gd3+, Tb3+ and Lu3+ in MTiO3 (M = Mg and Sr) luminescence properties

    Indian Academy of Sciences (India)

    Esra Korkmaz; Nilgun Ozpozan Kalaycioglu; V Emir Kafadar

    2013-11-01

    This paper reports Gd3+, Tb3+ and Lu3+ doped MTiO3 (M = Mg and Sr)-based phosphors which were synthesized by the conventional solid-state reaction method, their crystal structures and luminescence properties were investigated. X-ray diffraction patterns (XRD) showed that phosphors sintered at 1000 °C for 2 h were the pure SrTiO3 and MgTiO3 phases. The optimization of reaction conditions was carried out by thermogravimetry and differential thermal analysis (DTA/TG) methods. Surface and elemental analyses were performed by using SEM instrument. The excitation and emission spectra were recorded by a photoluminescence spectrophotometer (PL). The thermoluminescence (TL) properties of MgTiO3:RE (RE = Gd3+, Tb3+, Lu3+) and SrTiO3:RE (RE = Gd3+, Tb3+, Lu3+) were investigated.

  16. Commissioning ShARCS: the Shane Adaptive optics infraRed Camera-Spectrograph for the Lick Observatory 3-m telescope

    CERN Document Server

    McGurk, Rosalie; Gavel, Donald; Kupke, Renate; Peck, Michael; Pfister, Terry; Ward, Jim; Deich, William; Gates, John; Gates, Elinor; Alcott, Barry; Cowley, David; Dillon, Daren; Lanclos, Kyle; Sandford, Dale; Saylor, Mike; Srinath, Srikar; Weiss, Jason; Norton, Andrew

    2014-01-01

    We describe the design and first-light early science performance of the Shane Adaptive optics infraRed Camera-Spectrograph (ShARCS) on Lick Observatory's 3-m Shane telescope. Designed to work with the new ShaneAO adaptive optics system, ShARCS is capable of high-efficiency, diffraction-limited imaging and low-dispersion grism spectroscopy in J, H, and K-bands. ShARCS uses a HAWAII-2RG infrared detector, giving high quantum efficiency (>80%) and Nyquist sampling the diffraction limit in all three wavelength bands. The ShARCS instrument is also equipped for linear polarimetry and is sensitive down to 650 nm to support future visible-light adaptive optics capability. We report on the early science data taken during commissioning.

  17. Tributos sobre a folha ou sobre o faturamento? Efeitos quantitativos para o Brasil

    Directory of Open Access Journals (Sweden)

    Tiago V Cavalcanti

    2008-09-01

    Full Text Available Este artigo estuda os impactos alocativos e de bem-estar de uma reforma tributária que substitui os impostos sobre a folha de salários por outro que incide sobre a receita. Para isso, desenvolve-se um modelo neoclássico de crescimento econômico com impostos sobre a receita e sobre a folha de salários. As simulações com parâmetros da economia brasileira mostram que tal reforma tributária tem um efeito negativo no bem-estar, no estoque de capital de longo prazo e consequentemente no produto per capita de longo prazo. Contudo, o emprego aumenta.This paper studies the impacts of a tax reform which substitutes taxes on labor income by taxes on total revenue. In order to accomplish that, we construct and solve a general equilibrium neoclassical growth model with taxes on labor income and total revenue. The numerical simulations with Brazilian parameters show that such tax reforms would negatively affect welfare, the capital stock, and consequently per capita output. However, employment would increase. Such effects are quantitatively important.

  18. Establishmant of a real-time fluorescent quantitative method far detection of VEGF-C mRNA/VEGFR-3mRNA expression and its application%VEGF-C mRNA和VEGFR-3 mRNA实时荧光定量检测方法的建立及初步应用

    Institute of Scientific and Technical Information of China (English)

    卢培; 陆慧琦; 韩焕兴; 朱学源; 黄秋芳; 龚炜

    2009-01-01

    Objective To establish a real-time fluorescent quantitative reverse transcription pol-ymerase chain reaction (FQ-RT-PCR) method for detecting the expression levels of VEGF-C mRNA and VEGFR-3 mRNA,and explore its clinical application in esophageal carcinoma. Methods The real-time FQ-RT-PCR for detecting VEGF-C mRNA and VEGFR-3 mRNA was espabished based on Taq-Man fluorescent probe technology. In this method pMD18-VEGF-C and pMD18-VEGFR-3 were used as standard plasmid and RNA quantification was based on the threshold cycle (Ct) values to examine the specific expression of VEGF-C mRNA and VEGFR-3 mRNA in esophageal carcinoma. Results The detection linear range of the assay: VEGF-CmRNA and VEGFR-3 mRNA was both 103~ 108 copies/μg total RNA. The interassay and intraassay coefficient o{ variation of VEGF-C mRNA lower value was 7.07% and 9.04% respectively,7.55% and 10.28% for higher value respectively; the in-terassay and intraassay coefficient of variation of VEGFR-3 mRNA lower value was 7.69% and 12. 49% respectively,7.31% and 0.17%for higher value respectively. TheVEGF-C mRNA and theVEGFR-3 mRNA range in carcinoma tissue from 24 patients with lymphatic metastasis of esophageal carcinoma was 3.69×104-9.44 × 106 copies/μg total RNA and 2.54 × 104-8.03 × 106 copies/μg total RNA respectively, the mean value was 2.18 × 106 copies/μg total RNA and 2.27 × 106 copies/μg total RNA respectively. The VEGF-C mRNA and VEGFR-3 mRNA range in carcinoma tissue from 16 pa-tients without lymphatic metastasis of esophageal carcinoma was 2.32 × 103-5.85 × 105 copies/μg total RNA and 7.31 × 102-8.21 × 104 copies/μg total RNA respectively,the mean value was 1.08×105 cop-ies/μg total RNA and 1.68 ×104 copies/μg total RNA respectively. The VEGF-C mRNA and VEGFR-3 mRNA copy number per microgram of total RNA in carcinoma tissue from patients with lymphatic metastasis of esophageal carcinoma was significantly higher than that in carcinoma tissue from patients without

  19. Expression of T cell immunogloblin and mucin domain-containing molecule 3 mRNA and its relationship with asthma%T淋巴细胞免疫球蛋白黏蛋白-3 mRNA表达在支气管哮喘中的作用

    Institute of Scientific and Technical Information of China (English)

    韩锋; 陆小霞; 王莹

    2014-01-01

    Objective To detect the expression of T cell immunogloblin and mucin domain-containing molecule 3 (Tim-3) mRNA in peripheral blood mononuclear cells (PBMC) isolated from asthmatic children and asthmatic murine,and to explore the role of Tim-3 in bronchial asthma.Methods Recruiting 97 cases asthmatic children,47 children with acute asthma exacerbation(acute attack group),50 children with asthma remission (remittent group)and 42 children as the healthy control group.The Tim-3 mRNA expression was measured by using reverse transcription-polymerase chain reaction(RT-PCR) method.The levels of interleukin-6 (IL-6) and transforming growth factor-5 (TGF-β)were determined with enzyme-linked immunosorbent assay (ELISA),and to analyze the correlation between Tim-3 mRNA and the level of IL-6.The asthmatic murine models were randomly divided into 2 groups:normal control group and asthma group.There were 10 mice in each group.PBMC in each group were collected.Expression of Tim-3 mRNA was detected by using real-time PCR.The level of CD4 + IL-17 + and CD4 + CD~ + FoxP3 + which reflected Th17 and regulatory T cells(Treg) expression respectively were detected by using flow cytometry,and the correlation between Tim-3 and Thl7/Treg level was analyzed.Results Expression of Tim-3 mRNA in children with acute asthma exacerbation was significantly higher than those in remission stage and healthy control group (all P < 0.05).The expression of Tim-3 mRNA in children with asthma remission was significantly higher than that in healthy control group (P < 0.05),and the level of IL-6 in children with acute asthma exacerbation was significantly higher than those in remission stage and healthy control group (all P < 0.05).In the murine model of asthma group,the level of Tim-3 mRNA in PBMC was significantly higher than that in normal control group (P < 0.01),and in asthma group CD4 + IL-17 + expression was significantly higher than normal control group but CD4 + CD25 + FoxP3 + was

  20. β-catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase M3 mRNA

    Institute of Scientific and Technical Information of China (English)

    Yu-Sang Li; Min Liu; Yoshihiro Nakata; He-Bin Tang

    2011-01-01

    AIM: To identify the differentially over-expressed genes associated with β-catenin accumulation in nuclei of hepatocellular carcinoma (HCC) cells.METHODS: Differentially expressed genes were identified in radiation-induced B6C3 F1 mouse HCC cells by mRNA differential display, Northern blot and RT-PCR,respectively. Total glutathione-s-transferase (GST) activity was measured by GST activity assay and β-catenin localization was detected with immunostaining in radiation-induced mouse HCC cells and in HepG2 cell lines.RESULTS: Two up-regulated genes, glutamine synthetase and glutathione-s-transferase M3 (GSTM3), were identified in radiation-induced mouse HCC cells. Influence of β-catenin accumulation in nuclei of HCC cells on upregulation of GSTM3 mRNA was investigated. The nearby upstream domain of GSTM3 contained the β-catenin/Tcf-Lef consensus binding site sequences [5'-(A/T)(A/T)CAAAG-3'], and the total GST activity ratio was considerably higher in B6C3F1 mouse HCC cells with β-cateninaccumulation in nuclei of HCC cells than in those withoutβ-catenin accumulation (0.353 ± 0.117 vs 0.071 ± 0.064,P < 0.001). The TWS119 (a distinct GSK-3β inhibitor)-induced total GST activity was significantly higher in HepG2 cells with β-catenin accumulation than in those withoutβ-catenin accumulation in nuclei of HCC cells. Additionally,the GSTM3 mRNA level was significantly higher at 24 h than at 12 h in TWS119-treated HepG2 cells.CONCLUSION: β-catenin accumulation increases GST activity in nuclei of HCC cells, and GSTM3 may be a novel target gene of the β-catenin/Tcf-Lef complex.

  1. CAST3M modelling of a spent fuel assembly bending during a handling accident Rod failure risk evaluation from the experimental results of spent fuel rod bending test

    International Nuclear Information System (INIS)

    The fuel handling operating rules exclude any accidental risk. However in the framework of the PRECCI R and D project, the bending of a spent fuel assembly resulting from its locking during a translation displacement is taken into account. This enabled us to develop an approach based on experiments and calculations that allows us to simulate the behaviour of an assembly under such loading. This study was carried out in CEA laboratories with the funding and the technical support of EDF. A three points bending test on a spent fuel rod segment was performed at the Laboratory for Mechanical Behaviour of Irradiated Materials (LCMI). From the experimental strength-displacement curve, a maximum failure strain, a maximum failure curvature and an equivalent constitutive equation were determined. CAST3M modelling of the fuel rod taking into account the elasto-plastic behaviour of the clad and the cracking of the UO2 fuel pellets was verified by the experimental results. Consequently, the identification of the respective contributions of the clad and of the pellets to the rod global behaviour was made possible. A two dimensional assembly with beam elements was modelled with CAST3M. The properties of the beams modelling the different parts of the assembly (top and bottom nozzle, grids) were chosen and adjusted according to their materials (zirconium alloys, steel) in order to obtain stiffness, tensile and shear behaviour, sliding and holding functions close to the experimental ones. Assembly bending calculations were performed. In order to obtain a rod integrity estimator, their maximum calculated strains and curvatures as a function of the bending angles can be compared to the failure experimental ones. (authors)

  2. Density functional theory studies on theelectronic, structural, phonon dynamicaland thermo-stability properties of bicarbonates MHCO3, M D Li, Na, K

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Yuhua; Zhang, Bo; Sorescu, Dan C.; Johnson, Karl; Majzoub, Eric H; Luebke, David R.

    2012-07-01

    The structural, electronic, phonon dispersion and thermodynamic properties of MHCO3 (M D Li, Na, K) solids were investigated using density functional theory. The calculated bulk properties for both their ambient and the high-pressure phases are in good agreement with available experimental measurements. Solid phase LiHCO3 has not yet been observed experimentally. We have predicted several possible crystal structures for LiHCO3 using crystallographic database searching and prototype electrostatic ground state modeling. Our total energy and phonon free energy .FPH/ calculations predict that LiHCO3 will be stable under suitable conditions of temperature and partial pressures of CO2 and H2O. Our calculations indicate that the HCO 3 groups in LiHCO3 and NaHCO3 form an infinite chain structure through O H O hydrogen bonds. In contrast, the HCO 3 anions form dimers, .HCO 3 /2, connected through double hydrogen bonds in all phases of KHCO3. Based on density functional perturbation theory, the Born effective charge tensor of each atom type was obtained for all phases of the bicarbonates. Their phonon dispersions with the longitudinal optical–transverse optical splitting were also investigated. Based on lattice phonon dynamics study, the infrared spectra and the thermodynamic properties of these bicarbonates were obtained. Over the temperature range 0–900 K, the FPH and the entropies (S) of MHCO3 (M D Li, Na, K) systems vary as FPH.LiHCO3/ > FPH.NaHCO3/ > FPH.KHCO3/ and S.KHCO3/ > S.NaHCO3/ > S.LiHCO3/, respectively, in agreement with the available experimental data. Analysis of the predicted thermodynamics of the CO2 capture reactions indicates that the carbonate/bicarbonate transition reactions for Na and K could be used for CO2 capture technology, in agreement with experiments.

  3. Consideraciones criminológicas sobre las bandas juveniles

    OpenAIRE

    Medina, Juanjo, Ralphs, Robert, Aldridge, Judith

    2010-01-01

    Este artículo ofrece una serie de reflexiones originales sobre la definición de las bandas juveniles y resume algunos de los debates claves en el campo de investigación sobre bandas. En particular, se presta especial atención a los estudios sobre la relación entre bandas y delincuencia, las teorías que explican la formación de las bandas y los factores que empujan a los jóvenes a vincularse a las mismas, los estudios sobre respuestas de política criminal a este fenómeno, ...

  4. Influences of Inhaled Corticosteroids on CD4+ CD25+ Regulatory T Cells and Foxp3 mRNA of Asthmatic Patients%吸入激素对哮喘患者外周血CD4+CD25+调节性T细胞水平及Foxp3mRNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    薛克营; 柯明耀; 姜燕; 陈玲玲; 吴雪梅; 谢红旗

    2011-01-01

    目的 观察支气管哮喘患者外周血CD4 CD25调节性T细胞(CD4CD25Treg)、Foxp3 mRNA的水平及吸入糖皮质激素对其的影响.方法 流式细胞仪检测非急性发作期哮喘患者吸入激素前、后和健康志愿者(正常对照组)外周血单个核细胞(PBMCs)中CD4CD25Treg的比例,RT-PCR检测Foxp3 mRNA表达变化,肺功能仪检测第1秒用力呼气容积占预计值百分比(FEV.%pred)和呼气峰流量(PEF).结果 哮喘组治疗前CD4CD25Treg水平及Foxp3 mRNA的表达显著低于正常对照组(PCD25Treg水平及Foxp3 mRNA的表达较治疗前显著升高(P%pred、PEF显著低于正常对照组(P%pred、PEF较治疗前显著增加(PCD25Treg数量减少,功能下降,参与了哮喘的发病过程;吸入激素可以上调哮喘患者外周血CD4CD25Treg及Foxp3 mRNA的水平,改善哮喘患者的肺功能.%Objective To investigate the percentage of CD4+ CD25+ Treg cells and expression of Foxp3 mRNA in asthmatic patients and the impacts of inhaled steroids.Methods The percentages of CD4 + CID25 + Treg cells was assayed by flow cytometry and the expression of Foxp3 mRNA was detected by RT-PCR in peripheral blood mononuclear cells from the patients with chronic persistent asthma before and after steroids inhalation in comparison with healthy control.The forced expired volum in one second/predicted value( FEV1 % pred)and peak expired flow (PEF) were measured by spirometry.Results The level of CD4 + CD25 + Treg cells and the expression of Foxp3 mRNA were lower in asthmatics before steroids treatment than those in control ( P < 0.05 ) which were increased significantly after steroids treatment ( P < 0.05 ).FEV1 % pred and PEF were declined significantly than those in control but improved markedly after treatment (P < 0.05 ).Conclusions The insufficiency of amount and function of immue-suppressive CD4 + CD25 + Treg cells may play a role in the pathogenesis of asthma.Inhaled steroids can improve the lung function of asthmatics

  5. Sobre los límites

    Directory of Open Access Journals (Sweden)

    Walter Cabrera-Febola

    2014-10-01

    Full Text Available El intercambio de información entre entes naturales se produce a través de los boundaries [límites], este hecho reclama un estudio sistemático de ellos, lo cual hasta el momento no se ha realizado. En el presente trabajo, establecemos el concepto general de boundary, para luego identificar ciertos tipos de boundaries como interface, límite, borde y algunos de sus tipos, y barrera son identificados y conceptualizados. Luego realizamos un estudio parcial de algunos de los boundaries conceptualizados, tratando de analizarlos lo más posible. Finalmente, se da una discusión general sobre la existencia e importancia de los boundaries remarcando la generalidad y robustez del concepto de boundary y sus diferentes tipos, de aquí su utilidad en la ciencia y la tecnología es posible de apreciarse. Por último se comenta sobre su perspectiva en ciencia y tecnología.

  6. Expression and Significance of RORC and Foxp3 mRNA in Peripheral Blood Mononuclear Cells (PBMC) in Children with Bronchial Asthma%哮喘患儿外周血RORC和Foxp3mRNA表达水平的变化及其意义

    Institute of Scientific and Technical Information of China (English)

    黄雪琼; 檀卫平; 麦贤弟; 吴葆菁; 蓝丹

    2012-01-01

    [Objective] To investigate the mRNA expression and significance of RORC (the transcription factor of Thl7 cells) and Foxp3 (the transcription factor of Treg cells) in PBMC in children with bronchial asthma. [Methods] To detect the mRNA expressions of RORC and Foxp3 in PBMC by quantitative real-time PCR in 40 asthmatic children, including 20 children of acute attack group (age 8.5 ±2.3) , 20 children of remission group (age 9.2 ±1.8) and 10 children of healthy control (age 8.0 ± 1.6). To analyze the relationship between the RORC and Foxp3 mRNA expressions and the FEV1 of pulmonary function in asthmatic children. [Results] It was showed that RORC mRNA expressions in asthmatic children was higher in attack stage than in remission stage and in control group (5.41 ± 0.12 vs 3.33 ± 0.27 vs 3.78 ±0.13, P 0.05). The ratio of RORC/Foxp3 mRNA in PBMCs of asthmatic children in attack stage was significantly higher than those in remission stage and healthy controls (1.68 ± 0.09 vs 0.76 ± 0.06 vs 0.92 ± 0.04, P < 0.01). Pearson correlation analysis revealed that RORC mRNA was negatively correlated with FEV,, but Foxp3 mRNA was positively correlated with FEV,(r = -0.58 and 0.52, P < 0.01). [Conclusions] The imbalance of RORC/Foxp3 mRNA expression exists in asthmatic children, suggesting a potential role forThl7/Treg imbalance in the pathogenesis and reduction of lung function in asthmatic children.%[目的]研究淋巴细胞亚群Th17与Treg上游调控基因维甲酸相关孤儿核受体(RORC)、叉状头转录因子P3( Foxp3) mRNA在支气管哮喘患儿外周血单个核细胞中的表达变化,并探讨其临床意义.[方法]采用荧光实时定量PCR技术分别检测20例哮喘发作期(年龄8.5±2.3)和20例哮喘缓解期(年龄9.2±1.8)外周血单个核细胞的RORC和Foxp3mRNA表达水平,并与10例健康对照组(年龄8.0±1.6)进行比较.并将哮喘患儿RORC和Foxp3 mRNA表达水平与其同期肺功能第一秒用力呼气容积(FEV1)进行相关

  7. 新型材料3M Ketac Molar超硬玻璃离子与银汞合金充填后牙窝洞的对比%Comparative study on filling dental cavities with new material 3M Ketac Molar ultrahard glass ionomer cements and silver amalgams

    Institute of Scientific and Technical Information of China (English)

    熊轶

    2009-01-01

    背景:近年来,传统的银汞合金充填修复的缺点已日益显现.寻找其替代产品是目前研究的热点,而新型材料3M Ketac Molar 超硬玻璃离子充填修复的报道尚不多见.目的:比较3M Ketac Molar超硬玻璃离子与银汞合金充填后牙窝洞的临床效果.设计、时间及地点:回顾性分析,对照观察,于2002-02/2006-04在南昌市第九医院口腔科完成.对象:选择南昌市第九医院口腔科门诊就诊的后牙龋病患者187例307颗牙,平均年龄45岁.方法:用3M Ketac Molar后牙超硬玻璃离子填162颗后牙窝洞,银汞合金充填145颗后牙窝洞,连续观察1,2年,评价其临床效果,以充填材料完好,边缘密合,无继发龋、无磨损者为治疗成功.主要观察指标:两种材料修复后牙窝洞1,2年临床疗效.结果:3M Ketac Molar后牙超硬玻璃离子和银汞合金充填1年复查,成功率分别为96.30%,91.03%;2年复查,成功率分别为91.36%,90.34%.两组疗效差异无显著性意义(P>0.05).结论:3M Ketac Molar后牙超硬玻璃离子既能修复缺损牙面,而且改善美观,防龋,是替代银汞合金的较好材料.

  8. 支气管哮喘患者外周血CD4+ CD25+调节性T细胞水平及Foxp3 mRNA表达的分析%CD4+ CD25+ regulatory T cells and expressions of forkhead/winged helix transcription factor ( Foxp 3 ) mRNA in peripheral blood of patients with asthma

    Institute of Scientific and Technical Information of China (English)

    薛克营; 周咏明; 熊盛道; 熊维宁

    2006-01-01

    目的 观察支气管哮喘(哮喘)患者外周血单个核细胞(PBMCs)中CD4+ CD25+调节性T细胞(Treg)水平及叉状头/翅膀状螺旋转录因子(Foxp3)mRNA表达的变化,探讨CD4+ CD25+ Treg在哮喘发病中的作用.方法采用流式细胞仪检测78例哮喘患者(急性发作期组30例,慢性持续期组25例,缓解期组23例)和29例健康志愿者(正常对照组)PBMCs中CD4+ CD25+ Treg的比例;反转录-聚合酶链反应(RT-PCR)检测PBMCs中Foxp3 mRNA的表达.结果 急性发作期组和慢性持续期组PBMCs中CD4+ CD25+ Treg的比例及Foxp3 mRNA的表达明显低于缓解期组和正常对照组(P<0.05);缓解期组CD4+ CD25+ Treg的比例及Foxp3 mRNA的表达虽亦低于正常对照组,但差异无统计学意义(P>0.05);急性发作期组CD4+ CD25+ Treg的比例及Foxp3 mRNA的表达低于慢性持续期组(P<0.05).结论 哮喘患者外周血中具有免疫抑制活性的CD4+ CD25+ Treg数量减少,功能下降,可能参与哮喘的发生和发展.

  9. Topochemical fluorination of Sr3(M(0.5)Ru(0.5))2O7 (M = Ti, Mn, Fe), n = 2, Ruddlesden-Popper phases.

    Science.gov (United States)

    Romero, Fabio Denis; Bingham, Paul A; Forder, Susan D; Hayward, Michael A

    2013-03-18

    Reaction of the appropriate Sr3(M(0.5)Ru(0.5))2O7 (M = Ti, Mn, Fe), n = 2, Ruddlesden-Popper oxide with CuF2 under flowing oxygen results in formation of the oxide-fluoride phases Sr3(Ti(0.5)Ru(0.5))2O7F2, Sr3(Mn(0.5)Ru(0.5))2O7F2, and Sr3(Fe(0.5)Ru(0.5))2O(5.5)F(3.5) via a topochemical anion insertion/substitution process. Analysis indicates the titanium and manganese phases have Ti(4+), Ru(6+) and Mn(4+), Ru(6+) oxidation state combinations, respectively, while Mössbauer spectra indicate an Fe(3+), Ru(5.5+) combination for the iron phase. Thus, it can be seen that the soft fluorination conditions employed lead to formation of highly oxidized Ru(6+) centers in all three oxide-fluoride phases, while oxidation states of the other transition metal M cations remain unchanged. Fluorination of Sr3(Ti(0.5)Ru(0.5))2O7 to Sr3(Ti(0.5)Ru(0.5))2O7F2 leads to suppression of magnetic order as the fluorinated material approaches metallic behavior. In contrast, fluorination of Sr3(Mn(0.5)Ru(0.5))2O7 and Sr3(Fe(0.5)Ru(0.5))2O7 lifts the magnetic frustration present in the oxide phases, resulting in observation of long-range antiferromagnetic order at low temperature in Sr3(Mn(0.5)Ru(0.5))2O7F2 and Sr3(Fe(0.5)Ru(0.5))2O(5.5)F(3.5). The influence of the topochemical fluorination on the magnetic behavior of the Sr3(M(0.5)Ru(0.5))2O(x)F(y) phases is discussed on the basis of changes to the ruthenium oxidation state and structural distortions.

  10. 3M technology research based on robot system%基于机器人系统的3M技术研究

    Institute of Scientific and Technical Information of China (English)

    郭海冰; 王金涛; 封文江

    2012-01-01

    This paper introduces the application of robot system in 3M technology and its key technology in detail such as robot calibrate, machine vision and off-line programming technology. Through calibration the absolute precision of robot system can be unproved hugely, thus the robot can hand the measuring instrument to accomplish the measurement, then uses the robot system modeling and the equation of kinematics, constructs a model of the measuring data, creates the machining path of the uniform world coordinate system, transforms the path to the movement instruction of robot, and controls the robot to work, so the robot system is very important in the measuring, modeling and manufacturing ( 3 M ). Simultaneously, this paper introduces an integrated system of measuring, modeling and manufacturing which can satisfy the consumer and be applied to the rubbing-polishing field successfully.%介绍了机器人系统在3M技术中的应用,并详细介绍了机器人系统的关键技术:机器人标定技术、机器视觉技术和离线编程技术.经过标定后机器人系统绝对精度大幅度提高,可满足机器人“手持”测量工具进行测量的需要,同时通过机器人模型和运动学方程,将测量数据建模,生成统一世界坐标系下的加工路径,将生成的加工路径通过离线编程技术转化成机器人系统的运动指令,控制机器人进行加工,因此机器人系统在测量、建模和加工过程中发挥了非常重要的作用.同时介绍了一种机器人系统在3M技术中的典型应用,并开发了智能测量、建模及加工机器人一体化系统,该系统集成了透明件测量、自由曲面建模、机器人离线加工等先进技术,满足了用户需求,已经成功应用于透明件研磨抛光领域.

  11. Hábitos de consumo sobre la cerveza

    OpenAIRE

    Velasco Matilla, Débora

    2015-01-01

    Estudio de los hábitos de consumo de cerveza en un pueblo determinado situado en la provincia de Segovia, Cantalejo. Contiene un resumen sobre la historia de la cerveza y su tipología y un estudio de mercado sobre la cerveza partiendo de una encuesta. Grado en Comercio

  12. Violência sobre Crianças

    OpenAIRE

    Sacadura, Catarina Brito; Aragão, Maria José

    2014-01-01

    Trata-se de um estudo de revisão sobre a violência exercida sobre crianças, os agentes da violência, os sujeitos da violência, os factores de risco, as consequências na idade adulta e a recidividade de violência sexual.

  13. Algunas observaciones sobre el mundo actual

    OpenAIRE

    Tello, Ángel Pablo

    1993-01-01

    El artículo expone las nuevas condiciones políticas creadas en el mundo a partir de la caída del Muro de Brelín y la disolución de la Unión Soviética. Desde allí, el autor intenta reflexionar sobre las líneas de acción que emergen en el planeta como consecuencia de ello y de la ausencia de referencias globales que se observaron durante décadas. En particular, el ascenso de los nacionalismos que no sólo es un fenómeno que afecta a los países en desarrollo, sino también a las potencias industri...

  14. Algunas reflexiones sobre el turismo cultural

    Directory of Open Access Journals (Sweden)

    Claudia Toselli

    2006-01-01

    Full Text Available El presente artículo, si bien no pretende hacer un análisis exhaustivo sobre el turismo cultural, tiene por objetivo presentar algunas reflexiones acerca de esta modalidad turística desde diferentes aspectos. En primer lugar se abordará la relación entre turismo cultural y globalización, para luego centrarse en la incidencia de esta actividad como factor de desarrollo local y regional, haciendo referencia a algunos ejemplos de Argentina. Intentará también introducir acerca de los aspectos positivos y negativos, o puntos fuertes y débiles del turismo cultural. Y por último, esbozará algunas consideraciones acerca del rol de las organizaciones internacionales y de las principales agencias de cooperación internacional, incluyendo las resoluciones, declaraciones y recomendaciones más significativas en este campo del turismo.

  15. NOTAS SOBRE A LÓGICA ESTOICA

    Directory of Open Access Journals (Sweden)

    Valter Duarte Moreira Júnior

    2014-02-01

    Full Text Available Diante do grande desenvolvimento da Lógica e do cálculo proposicional no século XX, estudiosos do assunto em todo o mundo se concentraram em um rigoroso estudo dessa disciplina e sua história. Nesse processo, o eminente lógico polonês Jan Lukaziewicz descobriu em sua pesquisa sobre história da lógica a Lógica Estoica, que, já em III a. C., havia antecipado diversos métodos e conceitos da Lógica Moderna. Nossa intenção neste artigo é fazer um breve esboço da lógica desenvolvida pelos Estoicos.

  16. Reflexiones sobre el tratamiento ambulatorio de drogodependientes.

    Directory of Open Access Journals (Sweden)

    Juan Carlos González García

    1989-01-01

    Full Text Available Intentamos plantear algunas de las innumerables contradicciones, paradojas y mitos que se presentan en relación con las demandas y con las necesidades terapéuticas de los consumidores de drogas, desde el nivel de atención extrahospitalaria pública y dentro de una Unidad de Salud Mental. Se intenta reflexionar sobre los conocimientos teóricos y la realidad práctica, su interdependencia, complementariedad y divergencia, con la finalidad de evitar la huida asistencial o la omnipotencia terapéutica. Se valoran las diferencias existentes entre la farmacología teórica, anclada en el paradigma lewiniano, y la realidad clínica.

  17. Conceptos fundamentales sobre el mantenimiento de edificios

    Directory of Open Access Journals (Sweden)

    Juan Miguel Arencibia Fernández

    2007-01-01

    Full Text Available En esta investigación se realiza una profunda búsqueda sobre el tema del Mantenimiento de Edificios donde se abundan diferentes conceptos y criterios de la misma, encontrándose de esta forma los más utilizados métodos a emplear. Luego teniendo en cuenta las clasificación del Mantenimiento de Edificio según los tipos de obras, propietarios del inmueble y el momento que éste se realiza, como los costos de una edificación y su equipamiento a utilizar. Otros de los aspectos a tener en cuenta es la organización del Mantenimiento su planificación y responsabilidad, las ventajas que puede traer tanto para la economía y para el mismo usuario, como su vida útil, para el cual fueron ejecutadas las edificaciones.

  18. Sobre a moralidade do direito em Kant

    Directory of Open Access Journals (Sweden)

    Joãosinho Beckenkamp

    2009-07-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2009v8n1p63Na atual literatura sobre a fi losofi a prática de Kant há uma tendência a negligenciar a distinção feita na Metaphysik der Sitten entre direito (Jus e ética (Ethica, a ponto de ser a doutrina do direito de Kant vista como uma mera aplicação do imperativo categórico. Este artigo procura mostrar que Kant apresenta em sua doutrina do direito uma série de argumentos que logram estabelecer o direito de modo inteiramente independente da ética.

  19. Neruda e Drummond: um olhar sobre Stalingrado

    Directory of Open Access Journals (Sweden)

    Moacir Lopes de Camargos

    2015-07-01

    Full Text Available Este artigo tem por objetivo promover uma aproximação entre dois expoentes da lírica latino-americana do século XX, a saber: Pablo Neruda e Carlos Drummond de Andrade, a partir da análise dos poemas Canto a Stalingrado (1942 e Carta a Stalingrado (1943. Apresentaremos a visão histórica desses poetas sobre a Batalha de Stalingrado, considerada um dos principais eventos da Segunda Guerra Mundial. Ademais, será abordada a questão do engajamento político, que envolve a produção poética dos referidos autores.

  20. NOTAS SOBRE A LÓGICA ESTOICA

    OpenAIRE

    Valter Duarte Moreira Júnior

    2014-01-01

    Diante do grande desenvolvimento da Lógica e do cálculo proposicional no século XX, estudiosos do assunto em todo o mundo se concentraram em um rigoroso estudo dessa disciplina e sua história. Nesse processo, o eminente lógico polonês Jan Lukaziewicz descobriu em sua pesquisa sobre história da lógica a Lógica Estoica, que, já em III a. C., havia antecipado diversos métodos e conceitos da Lógica Moderna. Nossa intenção neste artigo é fazer um breve esboço da lógica desenvolvida pelos Estoicos....

  1. Apuntes sobre el Cultivo del Cacao

    Directory of Open Access Journals (Sweden)

    Ochoa Horacio

    1940-03-01

    Full Text Available Por muchos años permaneció el cultivo del cacao en nuestro país, en un deplorable atraso técnico; el agricultor a duras penas si tenía conocimientos generales de su explotación y, de una industria que tuvo su auge debido a la extensividad de las plantaciones, hoy sólo resta una reducida porción de ella. ¿Qué factores operaron esa tan notoria reducción hasta el punto de que exportadores en otros tiempos nos convertimos en importadores obligados de ese producto? Hay muchas razones de orden técnico y de orden económico. Los cacaotaleros obtenían halagadoras retribuciones cuando el jornal consistía en la alimentación que se le daba a la peonada y cuando, generoso, añadía una sobretasa en dinero. Bajo ese sistema de explotación, el descuadre que pudiera ocasionar tanto las enfermedades criptogámicas como los plagas, no era suficiente como para provocar el pesimismo en el hacendado y por tanto inducirlo al abandono de la plantación. A medida que las condiciones sociales del campesino se fueron modificando y su standard de vida aumentaba, cambió fundamentalmente el mecanismo de la industria Se observó entonces que los árboles morían y que era pobre la producción; que lo que en tiempos pasados fuera un negocio lucrativo, se les había convertido en una actividad improductiva y, para controlar estos fenómenos que se generalizaban en todas las zonas cacaotaleras, opusieron la ignorancia, el rutinarismo y la desidia. Lentamente se han ido modificando los conceptos antiguos sobre el trabajo cultural y los cuidados que con relación a las enfermedades y plagas requiere este delicado cultivo; la rutina está echando paso atrás y las experiencias científicas que procuran la prosperidad del plantío, se ponen en práctica en algunas zonas . Esto da esperanza para la reconstitución de la industria cacaotalera en nuestro país, que cuenta con inmensas regiones de óptima calidad para hacerla florecer sobre bases nuevas, con

  2. Sobre el Boletín

    Directory of Open Access Journals (Sweden)

    Andrés Arias

    2014-03-01

    Full Text Available En la página de Internet de la Biblioteca Luis Ángel Arango se indica que una de la funciones principales del Boletín es la de reseñar la novedades bibliográfica que van apareciendo en el país. "Novedades": de lo nuevo, tanto en las publicaciones como en las reseñas. Es decir, si lo que asegura la página de la Biblioteca es cierto, quien se acerca al Boletín debe encontrarse con comentarios recientes sobre libros recientes. Con guía que le ayuden a elegir entre las mil ofertas que hay en el mercado bibliográfico. Pero bien sabemos que este objetivo no se cumple.

  3. Tim-3 mRNA Expression in Peripheral Blood Mononuclear Cells and Its Relationship with CD4+CD25+ Regulatory T Cells from Asthmatic Children%哮喘儿童外周血单个核细胞Tim-3mRNA的表达及其与CD4+CD25+调节性T细胞的关系

    Institute of Scientific and Technical Information of China (English)

    陆小霞

    2011-01-01

    目的 观察哮喘患儿外周血单个核细胞(PBMC)中Tim-3 mRNA的表达及其与CD4+CD25+调节性T细胞(Treg)的关系,探讨Tim-3在哮喘发生发展中的作用.方法 收集哮喘门诊或住院患儿73例,其中哮喘缓解期38例(缓解组),轻至中度急性发作期35例(发作组).利用RT-PCR检测哮喘患儿PBMC中Tim-3 mRNA的表达并做半定量分析,流式细胞术检测PBMC中的CD4+CD25+ Treg的水平(CD4+CD25+ Treg占CD4+T细胞的百分比).利用酶联免疫吸附试验(ELISA)检测血浆中白细胞介素6(IL-6)、转化生长因子β(TGF-β)的水平,并分析Tim-3 mRNA与CD4+CD25+ Treg、IL-6水平的相关性.结果 哮喘发作组PBMC中Tim-3 mRNA吸光度值为(0.86±0.17),与缓解组(0.39±0.11)和正常对照组(0.06±0.03)比较,差异具有统计学意义(均P<0.05),并且缓解组与正常对照组比较差异亦具有统计学意义(P<0.05).哮喘发作组外周血CD4+CD25+ Treg百分率为(8.35±1.67)%,与缓解组[(10.21±2.04)%]和正常对照组[(12.43±2.58)%]比较,差异均具有统计学意义(P<0.05),并且缓解组与正常对照组比较差异亦具有统计学意义(P<0.05);哮喘发作组血浆中IL-6水平为(78.35±14.59)pg/mL,与缓解组[(36.48±9.18)pg/mL]和正常对照组[(10.24±3.57)pg/mL]比较,差异均具有统计学意义(P<0.05),缓解组与正常对照组比较差异亦有统计学意义(P<0.05).3组血浆中TGF-β水平没有明显差异;哮喘发作组和缓解组PBMC中Tim-3 mRNA的表达水平与CD4+CD25+ Treg百分率均呈负相关(r=-0.81,-0.79,均P<0.05),与IL-6的水平呈正相关(r=0.87,0.83,均P<0.01).结论 哮喘患儿PBMC中Tim-3 mRNA表达增高参与哮喘的发生与发展,其机制可能与升高血浆IL-6,抑制CD4+CD25+ Treg的生成有关.%Objective To detect the expression of T cell immunoglobulin mucin 3 ( Tim-3)mRNA in pcripheral blood mono nuclear cells(PBMC)isolated from asthmatic children and analyze its rclationship with CD4+ CD25+ rcgulatory T cells

  4. Aspectos da pesquisa sobre tipologia textual

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Travaglia

    2014-03-01

    Full Text Available Este artigo chama a atenção dos pesquisadores sobre tipologiatextual, na área da Linguística Textual, sobre aspectos que sãoimportantes para que estas pesquisas gerem conclusões egeneralizações mais confiáveis. Os pontos comentados são: a anecessidade de uma teoria tipológica geral de textos que inclusivedetermine se as categorias de texto são todas da mesma natureza. Oautor propõe uma teoria geral; b a necessidade de estudos maishorizontalizados ou amplos que estabeleçam campos de pesquisa ede estudos mais verticalizados, que aprofundam o conhecimentode pontos específicos; c os aspectos metodológicos para superarproblemas no levantamento das categorias de texto existentes emuma sociedade e cultura, em suas diversas comunidades discursivase esferas de ação social; d a questão dos parâmetros e critérios paraconsiderar uma categoria de texto como sendo uma categoria e seela é de determinada natureza; e a questão dos critérios e parâmetrospara a caracterização das categorias de texto; f a necessidade deestudar as diversas relações de diferentes tipos que podem ocorrerentre as categorias de texto (de diferentes naturezas, tanto em suacomposição quanto em seu funcionamento sociodiscursivo; e g aatenção que merece a questão teminológica.

  5. Theoretical and experimental studies of formation and migration of oxygen vacancies in BaM x Ti1- x O3 (M = Zr, Ge)

    Science.gov (United States)

    Umeda, Yuji; Aman, Sanshiro; Kuwabara, Akihide; Moriwake, Hiroki

    2016-10-01

    The formation and migration energies of oxygen vacancies in pure BaTiO3, and BaM x Ti1- x O3 (M = Zr, Ge) are calculated by first-principles calculations to understand the effect of doping on the reliability of multilayer ceramic capacitors (MLCCs). The formation and migration energies of oxygen vacancies are found to be larger in BaZr x Ti1- x O3 than in BaTiO3. This finding could be one of the possible reasons behind the improved reliability of Zr-doped MLCCs materials. On the other hand, by substituting Ge, the migration energy of BaGe x Ti1- x O3 becomes larger than that of BaTiO3. This is despite the smaller oxygen vacancy formation energy in BaGe x Ti1- x O3 than in BaTiO3. Even though Zr and Ge are tetravalent in BaM x Ti1- x O3, their valence states are different after the formation of oxygen vacancies, providing an explanation for the differences in vacancy formation and migration energies between BaZr x Ti1- x O3 and BaGe x Ti1- x O3. Our theoretical results are further confirmed by experiments on these model systems.

  6. Rapid identification of a novel complex I MT-ND3 m.10134C>A mutation in a Leigh syndrome patient.

    Directory of Open Access Journals (Sweden)

    David K Miller

    Full Text Available Leigh syndrome (LS is a rare progressive multi-system neurodegenerative disorder, the genetics of which is frequently difficult to resolve. Rapid determination of the genetic etiology of LS in a 5-year-old girl facilitated inclusion in Edison Pharmaceutical's phase 2B clinical trial of EPI-743. SNP-arrays and high-coverage whole exome sequencing were performed on the proband, both parents and three unaffected siblings. Subsequent multi-tissue targeted high-depth mitochondrial sequencing was performed using custom long-range PCR amplicons. Tissue-specific mutant load was also assessed by qPCR. Complex I was interrogated by spectrophotometric enzyme assays and Western Blot. No putatively causal mutations were identified in nuclear-encoded genes. Analysis of low-coverage off-target mitochondrial reads revealed a previously unreported mitochondrial mutation in the proband in MT-ND3 (m.10134C>A, p.Q26K, a Complex I mitochondrial gene previously associated with LS. Targeted investigations demonstrated that this mutation was 1% heteroplasmic in the mother's blood and homoplasmic in the proband's blood, fibroblasts, liver and muscle. Enzyme assays revealed decreased Complex I activity. The identification of this novel LS MT-ND3 variant, the genomics of which was accomplished in less than 3.5 weeks, indicates that rapid genomic approaches may prove useful in time-sensitive cases with an unresolved genetic diagnosis.

  7. Rapid identification of a novel complex I MT-ND3 m.10134C>A mutation in a Leigh syndrome patient.

    Science.gov (United States)

    Miller, David K; Menezes, Minal J; Simons, Cas; Riley, Lisa G; Cooper, Sandra T; Grimmond, Sean M; Thorburn, David R; Christodoulou, John; Taft, Ryan J

    2014-01-01

    Leigh syndrome (LS) is a rare progressive multi-system neurodegenerative disorder, the genetics of which is frequently difficult to resolve. Rapid determination of the genetic etiology of LS in a 5-year-old girl facilitated inclusion in Edison Pharmaceutical's phase 2B clinical trial of EPI-743. SNP-arrays and high-coverage whole exome sequencing were performed on the proband, both parents and three unaffected siblings. Subsequent multi-tissue targeted high-depth mitochondrial sequencing was performed using custom long-range PCR amplicons. Tissue-specific mutant load was also assessed by qPCR. Complex I was interrogated by spectrophotometric enzyme assays and Western Blot. No putatively causal mutations were identified in nuclear-encoded genes. Analysis of low-coverage off-target mitochondrial reads revealed a previously unreported mitochondrial mutation in the proband in MT-ND3 (m.10134C>A, p.Q26K), a Complex I mitochondrial gene previously associated with LS. Targeted investigations demonstrated that this mutation was 1% heteroplasmic in the mother's blood and homoplasmic in the proband's blood, fibroblasts, liver and muscle. Enzyme assays revealed decreased Complex I activity. The identification of this novel LS MT-ND3 variant, the genomics of which was accomplished in less than 3.5 weeks, indicates that rapid genomic approaches may prove useful in time-sensitive cases with an unresolved genetic diagnosis. PMID:25118196

  8. EMR study of electronic and magnetic ordering in doped CaMn1-x,yMx,yO3 (M = Ru, Mo) perovskites

    International Nuclear Information System (INIS)

    X-band electron magnetic resonance of polycrystalline CaMn1-x,yMx,yO3 (M = Ru, 0 ≤ x≤ 0.5, M = Mo, 0≤ y ≤ 0.14) samples were performed at 120 K ≤ T ≤ 540 K. The observed anomalies of electron magnetic resonance parameters correlate pretty well with the temperatures of antiferro-, ferromagnetic-like and orbital/charge ordering transitions in these systems and specify phase diagrams obtained by order techniques. However, a strong difference between resonant properties of Ru- and Mo-doped series is observed in both paramagnetic and magnetically ordered states. To describe such a difference, the energy band diagrams, which comprise the deep impurity t2g-like states = eg-like conductive band for Ca Mn1-xRuxO3 and shallow impurity states + conductive band, both having eg-like symmetry, for CaMn1-yMoyO3, are proposed. Specific electrons' contribution to the electron magnetic resonance line width explains concentration and temperature dependences of this parameter in the paramagnetic state in considered systems. (author)

  9. Strain-dependent ferroic properties of doped LaMO{sub 3}(M=Mn or Co) and BiFeO{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, Kathrin; Rata, Diana; Herklotz, Andreas; Bilani, Orkidia; Dekker, Martina; Schultz, Ludwig [IFW Dresden, Postfach 270116, 01171 Dresden (Germany); Reibold, Marianne [Technische Universitaet Dresden, Speziallabor Triebenberg, 01328 Dresden (Germany); Biegalski, Michael; Christen, Hans [Oak Ridge National Laboratory, CNMS, PO Box 2008, Bethel Valley Rd., Oak Ridge, TN 37831 (United States)

    2010-07-01

    Elastic strain at epitaxially grown interfaces provides an efficient coupling mechanism in two-phase multiferroics: piezoelectric or magnetostrictive strain arising from application of an electric or a magnetic field is transferred readily between the components. We employ a piezoelectric single-crystalline substrate to apply reversible biaxial strain to epitaxially grown magnetic or ferroelectric films and study the strain response of their ferroic properties. The relaxor-based 0.72PbMg{sub 1/3}Nb{sub 2/3}O{sub 3} -0.28PbTiO{sub 3}(001) (PMN-PT) proved to be a favourable piezo-substrate with large, reversible, uniform in-plane strain which shows little temperature dependence. The magnetization vs. strain of doped LaMO{sub 3} (M=Mn or Co) phases has been studied. It reveals the impact of the strain-induced tetragonal lattice distortion on the ferromagnetic double exchange and the magnetic moment of Co ions that leads to moderate or large magnetization modulation. Further, the strain dependence of ferroelectric switching has been investigated for multiferroic BiFeO{sub 3}. It displays a large response of unexpected sign attributed to a strain influence on kinetics.

  10. Antiferromagnetic spin glass-like behavior in sintered multiferroic Aurivillius Bim+1Ti3Fem−3O3m+3 compounds

    International Nuclear Information System (INIS)

    The structure, hyperfine interactions and magnetic properties of the series of multiferroic Bim+1Ti3Fem−3O3m+3 Aurivillius compounds with m=4–8 were studied using X-ray diffraction, 57Fe Mössbauer spectroscopy and vibrating sample magnetometry. Samples were prepared by the conventional solid-state sintering method. Bulk magnetic measurements showed that for m=4 the compound is paramagnetic down to 2 K while in the compound with m=5 the antiferromagnetic type transition was observed at 11 K. In the case of compounds with m=6–8 much more complex magnetic behavior was found. For these compounds a gradual spin freezing and antiferromagnetic spin glass-like ordering were observed on decreasing temperature. The temperature of spin glass freezing was determined as 260, 280 and 350 K for m=6, 7 and 8, respectively. Room-temperature Mössbauer spectra of all the compounds studied confirm their paramagnetic state. However, liquid nitrogen and liquid helium temperature measurements reveal magnetic ordering with a residual paramagnetic phase contribution for the compounds with m=5–8. - Highlights: • Aurivillius compounds prepared by solid-state sintering. • Coexistence of antiferromagnetic and paramagnetic phases seen by Mössbauer spectra. • Hyperfine interactions parameters of compounds determined. • Antiferromagnetic spin glass-like ordering observed down to 10 K

  11. Competition between Alkalide Characteristics and Nonlinear Optical Properties in OLi3-M-Li3O (M=Li, Na and K) Complexes

    CERN Document Server

    Srivastava, Ambrish Kumar

    2016-01-01

    Alkalides possess enhanced nonlinear optical (NLO) responses due to localization of excess electrons on alkali metals. We have proposed a new class of alkalides by sandwiching alkali atoms (M) between two Li3O superalkali clusters at MP2/6-311++G(d,p) level. We notice a competition between alkalide characteristics and NLO properties in OLi3-M-Li3O (M=Li, Na and K) isomers. For instance, the atomic charge on M (qM) in D2h structure is -0.58e for M=Li and its first static mean hyperpolarizablity (\\b{eta}o) is 1 a.u., but in C2v structure, qM=-0.12e and \\b{eta}o= 3.4*103 a.u. More interestingly, the \\b{eta}o value for M=K (C2v) increases to 1.9*104 a.u. in which qM=0.24e. These findings may provide new insights into the design of alkalides, an unusual class of salts and consequently, lead to further researches in this direction.

  12. 3M Filtek Z350流动树脂与Pekaseal光固化窝沟封闭剂预防儿童龋病的临床效果研究%Comparison of Preventive Effect of 3M Filtek Z350 Flowable Resin and Pekaseal Light-Cured Sealant for Caries in Children

    Institute of Scientific and Technical Information of China (English)

    蒲寒秋; 肖世芳; 勾京东

    2013-01-01

      目的对比观察3M Filtek Z350流动复合树脂与Pekaseal光固化窝沟封闭剂预防儿童恒磨牙龋病的临床效果。方法对2009年1月至2011年6月间本院门诊符合纳入标准的126名6~10岁儿童的315颗恒磨牙随机分为两组,观察组选择3M Filtek Z350流动复合树脂进行窝沟封闭治疗(病例数=63,牙数=136),对照组采用Pekaseal光固化窝沟封闭剂进行窝沟封闭治疗(病例数=63,牙数=179),随访6个月~1年,复查封闭剂保留情况和患龋情况。结果术后6个月观察组和对照组窝沟封闭剂保留率无统计学差异(P>0.05),术后1年观察组封闭剂保留率高于对照组,差异有统计学意义(P<0.05)。术后6个月、1年,观察组患龋率均低于对照组,差异均有统计学意义(P<0.05)。结论采用3M Filtek Z350流动复合树脂进行窝沟封闭预防儿童恒磨牙窝沟龋效果显著,使龋病发生率大大降低,优于传统的窝沟封闭剂,值得临床推广应用。%Objective To compare the preventive effect of 3M Filtek Z350 flowable resin and Pekaseal light-cured pit and fissure sealant for caries in children. Methods One hundred and twenty six children aged 6 to 10 years were selected to perform sealant technique on their first permanent molars. First molars in trial group were sealed with 3M Filtek Z350 flowable resin and in control group were sealed with Pekaseal light-cured sealant. Sealant retention rate and caries prevalence were observed during 1-year follow up. Rusults At 6-month follow up, there were no statistical difference in sealant retention rate between the two groups(P>0.05). At 1 year follow up, the retention rate of flowable resin group was significantly higher than that of light-cured sealant group(P<0.05). However,caries prevalence of flowable resin group was significantly lower than that of light-cured sealant group at both 6-month and 1-year follow up(P<0.05).Conclusion 3M Filtek Z350 flowable

  13. Effect of Skullcap Bupleurum Chinense and Compatibility Extract on Expression of CVB3m -RNA and IFN mRNA in the Myocardium in Mice with Viral Myocarditis%黄芩柴胡及其配伍提取物对心肌炎小鼠心肌组织CVB3m RNA复制及IFNm RNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    刘芳; 王雪峰; 闫丽娟; 南春红; 岳志军; 杨贵将

    2010-01-01

    目的:研究黄芩、柴胡及其配伍提取物对心肌炎小鼠心肌组织CVB3m RNA复制及IFN mRNA表达的影响.方法:将Balb/c小鼠随机分为:柴胡组、黄芩组、配伍组,模型组和正常对照组.腹腔注射CVB3m病毒诱导Balb/c小鼠心肌炎模型.采用RT-PCR技术,检测各组小鼠给药后不同时间点心肌组织中CVB3m RNA的复制和IFN mRNA的表达情况.结果:3个给药组心肌组织中CVB3m-RNA的量明显低于模型对照组,其中黄芩组和配伍物组抗病毒作用明显:柴胡组和配伍组均可诱生干扰素,与模型组比较有显著差异.结论:黄芩提取物组具有明显抗病毒作用;柴胡在疾病早期具有明显抗病毒作用,且具有明显诱生干扰素的作用;配伍提取物组具有明显抗病毒和诱生干扰素作用,在疾病极期表现明显优势.

  14. High Expression, Purification and Characterization of cDNA Encoding M3-M4 Loop in the Essential Subuint of hNMDA Receptor%人NMDA受体主亚基M3-M4环基因片段的高效表达、纯化与鉴定

    Institute of Scientific and Technical Information of China (English)

    张玉梅; 孙长凯; 范明; 李伍举; 刘淑红; 赵杰; 韩大跃; 王嘉玺

    2003-01-01

    用基因工程方法获得人N-甲基-D-天冬氨酸(N-methyl-D-aspartate,NMDA)受体主亚基M3-M4环靶片段,以此为免疫原,用于进一步免疫原性及相关应用研究. 自人脑胶质瘤组织中提取总RNA, 采用RT-PCR扩增出人NMDA受体主亚基M3-M4环的基因片段, 并按照计算机辅助原核表达载体pBV220中外源基因高效表达的数学模型预测方法, 将其进行优化改构. 将目的基因克隆到pBV220中,转化大肠杆菌DH5α,升温诱导表达,从蛋白质水平检测重组体在大肠杆菌中的表达情况, 通过制备性SDS-PAGE 进行纯化, 从相对分子质量、免疫反应性、肽质谱指纹分析等方面进行鉴定. 结果表明,成功构建了人NMDA受体主亚基M3-M4环的原核表达载体(命名为pBV-NR1L3),通过基因优化,实现了高效表达.凝胶扫描分析表达量约占菌体总蛋白29 %,重组肽纯度达95 %以上.

  15. Expression and relationship of microRNA-31 and FOXP3 mRNAs in CD4 + T cells from a mouse asthma model%哮喘小鼠CD4+T细胞中microRNA-31和FOXP3mRNA的表达及相互关系的研究

    Institute of Scientific and Technical Information of China (English)

    酆孟洁; 史菲; 邱晨

    2012-01-01

    Objective To determine the expression levels of microRNA-31 and FOXP3 mRNAs in the spleen CD4 + T cells from asthma mice, and identify their relationship. Methods A total of 15 Balb/c mice were randomly divided into 3 groups, normal control group, model group, and dexamethasone treatment group. The murine asthma model was sensitized and challenged by ovalbumin ( OVA). The inflammatory cytokines IL-4 and IFN-γ in the bronchoalveolar lavage fluid ( BALF) in the 3 groups were measured by ELISA. Expression of microRNA-31 and FOXP3 mRNAs in spleen CD4 + T cells from the 3 groups were detected by quantitative real time-PCR assay. The relationship of the expression were also analyzed. Results The BALF level of IL-4 was increased in the model group (228.29 ±66. 18 pg/ml) compared with the normal control group (66.63 ± 17.33 pg/ml, P 0.05). There was no significant difference in levels of IFN-γ among the three groups( P > 0.05). The expression of FOXP3 Mrna in the spleen CD4 + T cells in the model group was 0. 10 times as great as in the normal control group (P 0. 05 ). The expressions of microRNA-31 Mrna in the splenn CD4+ T lymphocytes in the model group were 4.79 times as great as in the normal control (P 0. 05). Pearson correlation coefficient between microRNA-31 and FOXP3 Mrna was -0.609 (P<0.05). Conclusion There is a negative linear correlation between microRNA-31 and FOXP3 Mrna in asthma, and microRNA-31 and dexamethasone mayaffect the expression of FOXP3 Mrna via different pathways.%目的 初步探讨哮喘CD4+T细胞中microRNA-31和FOXP3的表达水平、两者的相关性及激素对它们的影响.方法 以卵蛋白(OVA)致敏激发建立哮喘小鼠模型.将15只BALB/c小鼠分为正常对照组、OVA组和地塞米松组,EHSA检测小鼠支气管肺泡灌洗液(BALF)中IL-4和IFN-γ水平;实时荧光定量PCR检测小鼠脾脏CD4+T细胞的microRNA-31和FOXP3 mRNA的水平,并分析二者之间的相关性.结果 OVA组BALF中IL-4

  16. Effects of TGF-β1 on the expression of MMP-1 and MMP-3 mRNA in skin fibroblasts induced by UVA in vitro%TGF-β1对UVA照射人皮肤成纤维细胞MMP-1和MMP-3 mRNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    何永静; 刘垠; 王继华; 赵亚南; 杨云; 李颖

    2010-01-01

    目的:研究转化生长因子-β1(tansforming gowth fctor-beta 1,TGF-β1)对长波紫外线(ultrayiolet A,OVA)照射人皮肤成纤维细胞基质金属蛋白酶-1(matrix metalloproteinasv-1,MMP-1)和基质金属蛋白酶-3(matrix metalloprotein ase-3,MMP-3)mRNA表达的影响,探讨TGF-β1对皮肤成纤维细胞的光保护机制.方法:通过体外培养人皮肤成纤维细胞,加入不同浓度TGF-β1(0.1、1、10ng/m1)预处理细胞后UVA15J/cm2照射诱导细胞光老化,用四甲基偶氮唑蓝(MTT)法检测成纤维细胞增殖活性,半定量逆转录聚合酶链反应(RT-PCR)测定MMP-1、MMP-3mRNA表达. 结果:UVA15J/cm2照射前给予不同剂量TGF-β1预处理,随TGF-β1剂量增加成纤维细胞增殖活性明显提高,MMP-1、MMP-3mRNA表达随着TGF-β1剂量增加而降低.结论:TGF-β1可提高UVA照射体外培养成纤维细胞增殖活性,减少UVA照射体外培养的皮肤成纤维细胞MMP-1、MMP-3 mRNA表达,减少其对胶原的降解,对UVA照射皮肤成纤维细胞起保护作用.

  17. Concretando la tercera misión (3m de la Universidad Pública Regional. Impactos y percepciones de un proyecto de extensión. Caso Universidad del Magdalena

    Directory of Open Access Journals (Sweden)

    Pablo Hernán Vera Salazar

    2014-08-01

    Full Text Available El propósito de este artículo es presentar un análisis de la orientación asumida por una universidad de la región Caribe colombiana para desarrollar acciones ubicadas en lo que se ha denominado “la tercera misión de la universidad”. Adicionalmente, se hace análisis del efecto generado en la universidad por la ejecución de proyectos de extensión. El enfoque metodológico utilizado fue el de estudio de caso tomando un proyecto de intervención de alcance regional como unidad de análisis. En este contexto, las fuentes de información utilizadas fueron: información documental de la ejecución del proyecto, entrevistas semiestructuradas a los coordinadores del proyecto y una encuesta de percepción sobre la tercera misión dirigida a una muestra de profesores de la universidad. El principal hallazgo de este estudio fue la identificación y caracterización de la orientación asumida por la universidad objeto de estudio para desarrollar la tercera misión con énfasis en el desarrollo social del entorno. Aunque este estudio se limitó a un único caso en un contexto particular, los hallazgos obtenidos permitieron evidenciar algunos rasgos de la materialización de la tercera misión de la universidad, los cuales pueden servir de referencia para desarrollar estudios similares en otros contextos institucionales de la región y del país.Palabras clave: Tercera misión; extensión universitaria; responsabilidad social Universitaria; gestión de proyectos; innovación social.Specifying the third mission (3m of the Regional Public University. Impacts and perceptions of extension project. Case: University of MagdalenaAbstractThe purpose of this paper is to present an analysis of the orientation that is assumed by a university in the Colombian Caribbean region for developing actions in what has been known as “the university’s third mission”. In addition, an analysis about the effect on the university that is generated by the execution of

  18. Photoluminescence properties of M{sub 2}Mg(BO{sub 3}){sub 2}:Sm{sup 3+} (M:Sr and Ba)

    Energy Technology Data Exchange (ETDEWEB)

    PEKGOeZLUe, Ilhan, E-mail: pekgozluilhan@yahoo.com [Bartin University, Faculty of Engineering, Department of Environmental Engineering, Bartin 74100 (Turkey)

    2013-02-15

    M{sub 2}Mg(BO{sub 3}){sub 2}:Sm{sup 3+} (M:Sr and Ba) phosphors were synthesized by a solution combustion synthesis method followed by heating of the precursor combustion ash at 900 Degree-Sign C in air. The synthesized materials were characterized by using the powder XRD. The emission and excitation spectra of these materials were measured at room temperature with a spectrofluorometer. Both Sr{sub 2}Mg(BO{sub 3}){sub 2}:Sm{sup 3+} and Ba{sub 2}Mg(BO{sub 3}){sub 2}:Sm{sup 3+} phosphors emit a strong in orange-red region. It was observed that the optimum concentration of Sm{sup 3+} in Sr{sub 2}Mg(BO{sub 3}){sub 2} and Ba{sub 2}Mg(BO{sub 3}){sub 2} are 0.01 and 0.04 mol, respectively. Finally, the relation between the photoluminescence properties of Sm{sup 3+} and host compositions was discussed in detail. - Highlights: Black-Right-Pointing-Pointer It has synthesized two novel inorganic borate phosphors for the first time. Black-Right-Pointing-Pointer The synthesized materials were characterized by using the powder X Ray Diffraction. Black-Right-Pointing-Pointer The photoluminescence properties of both phosphors were investigated using a spectrofluorometer. Black-Right-Pointing-Pointer Both Sr{sub 2}Mg(BO{sub 3}){sub 2}: Sm{sup 3+} and Ba{sub 2}Mg(BO{sub 3}){sub 2}: Sm{sup 3+} phosphors emit a strong in orange-red region.

  19. σ-Aromatic cyclic M3(+) (M = Cu, Ag, Au) clusters and their complexation with dimethyl imidazol-2-ylidene, pyridine, isoxazole, furan, noble gases and carbon monoxide.

    Science.gov (United States)

    Pan, Sudip; Saha, Ranajit; Mandal, Subhajit; Chattaraj, Pratim K

    2016-04-28

    The σ-aromaticity of M3(+) (M = Cu, Ag, Au) is analyzed and compared with that of Li3(+) and a prototype σ-aromatic system, H3(+). Ligands (L) like dimethyl imidazol-2-ylidene, pyridine, isoxazole and furan are employed to stabilize these monocationic M3(+) clusters. They all bind M3(+) with favorable interaction energy. Dimethyl imidazol-2-ylidene forms the strongest bond with M3(+) followed by pyridine, isoxazole and furan. Electrostatic contribution is considerably more than that of orbital contribution in these M-L bonds. The orbital interaction arises from both L → M σ donation and L ← M back donation. M3(+) clusters also bind noble gas atoms and carbon monoxide effectively. In general, among the studied systems Au3(+) binds a given L most strongly followed by Cu3(+) and Ag3(+). Computation of the nucleus-independent chemical shift (NICS) and its different extensions like the NICS-rate and NICS in-plane component vs. NICS out-of-plane component shows that the σ-aromaticity in L bound M3(+) increases compared to that of bare clusters. The aromaticity in pyridine, isoxazole and furan bound Au3(+) complexes is quite comparable with that in the recently synthesized Zn3(C5(CH3)5)3(+). The energy gap between the highest occupied molecular orbital and the lowest unoccupied molecular orbital also increases upon binding with L. The blue-shift and red-shift in the C-O stretching frequency of M3(CO)3(+) and M3(OC)3(+), respectively, are analyzed through reverse polarization of the σ- and π-orbitals of CO as well as the relative amount of OC → M σ donation and M → CO π back donation. The electron density analysis is also performed to gain further insight into the nature of interaction. PMID:26624276

  20. Alkaline Earth Metal Zirconate Perovskites MZrO3 (M=Ba(2+), Sr(2+), Ca(2+)) Derived from Molecular Precursors and Doped with Eu(3+) Ions.

    Science.gov (United States)

    Drąg-Jarząbek, Anna; John, Łukasz; Petrus, Rafał; Kosińska-Klähn, Magdalena; Sobota, Piotr

    2016-03-24

    The effect of alkaline earth metal alkoxides on the protonation of zirconocene dichloride was investigated. This approach enabled the design of compounds with preset molecular structures for generating high-purity binary metal oxide perovskites MZrO3 (M=Ba(2+), Sr(2+), Ca(2+)). Single-source molecular precursors [Ba4 Zr2 (μ6 -O)(μ3 ,η(2)-OR)8 (OR)2(η(2) -HOR)2 (HOR)2 Cl4], [Sr4 Zr2 (μ6 -O)(μ3 ,η(2)-OR)8 (OR)2 (HOR)4 Cl4], [Ca4 Zr2 (μ6-O)(μ3 ,η(2)-OR)8 (OR)2 Cl4], and [Ca6 Zr2 (μ2 ,η(2)-OR)12 (μ-Cl)2 (η(2) -HOR)4 Cl6 ]⋅8 CH2 Cl2 were prepared via elimination of the cyclopentadienyl ring from Cp2 ZrCl2 as CpH in the presence of M(OR)2 and alcohol ROH (ROH=CH3OCH2 CH2OH) as a source of protons. The resulting complexes were characterized by elemental analysis, IR and NMR spectroscopy, and single-crystal X-ray diffraction. The compounds were then thermally decomposed to MCl2 /MZrO3 mixtures. Leaching of MCl2 from the raw powder with deionized water produced highly pure perovskite-like oxide particles of 40-80 nm in size. Luminescence studies on Eu(3+)-doped MZrO3 revealed that the perovskites are attractive host lattices for potential applications in display technology. PMID:26891039

  1. Investigation of exchange bias in 0.1MFe2O4/0.9BiFeO3 (M=Co, Cu, Ni) nanocomposite

    International Nuclear Information System (INIS)

    The 0.1MFe2O4/0.9BiFeO3 (M=Co, Cu, Ni) nanocomposite samples were synthesized by the sol–gel method. Phase composition analysis was carried out, which showed that these bulk samples were composed of a ferrimagnetic MFe2O4 (M=Co, Cu, Ni) and a ferroelectric antiferromagnet (FEAF) BiFeO3 phases, respectively. The magnetic properties of all the samples were investigated by measuring their magnetization as a function of temperature and magnetic field. These results indicated that the magnetic hysteresis loops of 0.1CuFe2O4/0.9BiFeO3 sample sintered in air atmosphere at 550 °C for 3 h exhibited a negative shift and an enhanced coercivity at low temperature ascribed to strong exchange coupling between the BiFeO3 and CuFe2O4 grains. However, there were no magnetic hysteresis loops in both the 0.1CoFe2O4/0.9BiFeO3 sample and the 0.1NiFe2O4/0.9BiFeO3 sample. In view of these results, we tend to think the CuFe2O4/BiFeO3 nanocomposite system may be a useful multifunctional material. - Highlights: ► Exchange bias effect in ferroelectric antiferromagnet (FEAF)/ferromagnet (FM) nanocomposites. ► Exchange bias effect is only observed in the 0.1CuFe2O4/0.9BiFeO3 nanocomposite. ► Lower saturation magnetization is important for producing exchange bias in FEAF/FM system.

  2. Structural and soft magnetic properties of Fe73.5Nb3M1Si13.5B9 (M=Cu, Mn, Pt)

    International Nuclear Information System (INIS)

    The magnetic and the structural properties have been investigated for Fe73.5Nb3M1Si13.5B9 (M=Cu, Mn, Pt) alloys in their as-received and heat-treated state. Differential scanning calorimeter and scanning electrical resistivity were used to study crystallization behaviour and to examine the influence of the nucleation elements Cu, Mn and Pt on the structural and magnetic properties of Fe-based nanocrystalline materials. The temperature coefficient of resistivity above Curie temperature was found to be very low (0.2x10-4 K-1) in the Cu containing alloy as compared to the alloys which contained Mn or Pt. A broad exothermic DSC peak for the formation of Fe3Si nanoparticles was absent when Cu was replaced by Mn or Pt. Instead, a sharp exothermic peak for the formation of Fe3(SiB) phase was observed with an onset at 875 K. The magnetic properties of the three alloys measured after stress relaxed annealing were similar. However, after first-stage crystallization, the soft magnetic properties were further enhanced only in Cu containing alloys due to the formation of Fe3Si nanoparticles. Such nanoparticles together with different intermetallic phases like FeMn3 or FePt3 were formed in Mn or Pt containing alloys. Moreover, the NbFeSi phase was also formed in the latter alloys after higher temperature annealing which reduced not only the amount of the Fe3Si phase but also the grain refining effect due to the lesser amount of Nb available at the grain boundary. When Cu was replaced by Mn or Pt, the formation of different intermetallics reduced the volume fraction of Fe3Si nanoparticles and the lesser amount of grain refining Nb made the materials magnetically inferior after annealing above 775 K

  3. Ab initio investigation of the oxygen reduction reaction activity on noble metal (Pt, Au, Pd), Pt3M (M = Fe, Co, Ni, Cu) and Pd3M (M = Fe, Co, Ni, Cu) alloy surfaces, for Lisbnd O2 cells

    Science.gov (United States)

    Sankarasubramanian, Shrihari; Singh, Nikhilendra; Mizuno, Fuminori; Prakash, Jai

    2016-07-01

    First principles, density functional theory (DFT) modelling of the oxygen reduction reaction (ORR) on noble metal (Pt, Au, Pd), Pt3M (M = Fe, Co, Ni, Cu) and Pd3M (M = Fe, Co, Ni, Cu) alloy surfaces, was carried out. Periodic models of close-packed (111) surfaces were constructed, their geometry was optimized and the most stable geometric surface configuration was identified. The correlation between the intermediate species binding energy and the favored reaction pathway from amongst 1e-, 2e-, and 4e- mechanisms were studied by calculating the binding energies of a 1/4 monolayer of O, O2, LiO, LiO2, Li2O2, and Li2O on various sites and orientations. The reaction free energies (ΔGrxn) were calculated and used to compute the catalytic activity of the surfaces using molecular kinetics theory. Plots of the catalytic activity vs. Oxygen binding energy (EBinding (O)) showed a typical "volcano" profile. The insights gained from this study can be used to guide the choice of cathode catalysts in Lisbnd O2 cells.

  4. Therapeutic effect of Skullcap,Bupleurum chinense and compatibility extract on the mice with Coxsackievirus B3m myocarditis%黄芩、柴胡及其配伍提取物对柯萨奇病毒B3m 感染Balb/c小鼠心肌炎治疗作用

    Institute of Scientific and Technical Information of China (English)

    刘芳; 王雪峰; 南春红; 闫丽娟; 岳志军; 孟宪生

    2011-01-01

    Objective: To explore the therapeutic effect of Skullcap extract (SE), Bupleurum chinense extract (BCE) and compatibility extract (CE) on the mice with viral myocarditis. Methods: Viral myocardititis (VMC) model was induced by an intraperitoneal injection of Coxsackievirus B3m (CVB3m) in the BALB/c mouse. After the model was confirmed, the three treatment groups were administered with SE, BCE and CE separately. The general state, heart / body mass, survival rate, myocardial pathologic score and CVB3m viral titer in the myocardium in all groups were observed. Result: The general state, heart / body mass, survival rate, myocardial pathologic score of mice in the three treatment groups compared with the model control group were improved obviously. The viral titers of three treatment groups significantly decreased compared with the model group. The myocardial pathologic score in BCE and CE gruops significantly decreased compared with SE group.The viral titers of SE group were significantly lower than BCE group. Conclusion: Bupleurum chinense extrac significantly reduced myocardial pathologic damage.skullcap extrac can inhibited virus multiplication obviously. Compatibility extract can both inhibited virus multiplication and reduce cardiac pathological damage.%目的:探讨黄芩、柴胡及其配伍提取物对柯萨奇病毒B3m(CVB3m)感染小鼠心肌炎的治疗作用.方法:采用腹腔注射CVB3m诱导Balb/c小鼠心肌炎模型,用黄芩、柴胡及其配伍提取物对此动物模型进行治疗,观察各组小鼠给药后不同时间点的一般状态、存活率、心脏/体质量比值、心肌组织病理积分和心肌CVB3m病毒滴度情况.结果:3组药物均能不同程度改善模型小鼠的一般状态、心脏/体质量比值、存活率及心肌组织病理积分,同时降低模型小鼠的心肌组织病毒滴度;柴胡组和配伍组心肌组织病理积分明显低于黄芩组;黄芩组的病毒滴度明显低于柴胡组.结论:柴胡在减轻

  5. El puente Bendorf sobre el Rin (Alemania

    Directory of Open Access Journals (Sweden)

    Hirschfeld, Kurt

    1966-03-01

    Full Text Available This recently completed bridge over the Rhine is 524 m long, and is a reinforced concrete structure, built by successive overhangs, without the aid of formwork or scaffolding. The centre span is 208 m in length, and the other six vary between 43 and 71 m. The deck consists of two independent parts, including a continuous box girder, with a hinge at the crown of the main span. It is stiffened with transversal diaphragms, spaced every 34 m. The piles rest on pneumatic caissons, which go down to 16 m below the river bed. The attachment between the piles and the caissons is rigid, at the central pile, and at the other piles it operates through a roller bearing. The central span was constructed without intermediate supports for the first 40 m, and beyond that stage, for greater safety, a provisional movable tower was built, as a temporary point of support for the free overhang. The various sections were concreted and post-tensioned with 32 mm bars, by the Dywidag procedure. Account was taken of the varying deformations that took place at each section, so as to add the necessary counter-deflection that finally enabled the two sides of the arch to meet at the crown at the calculated point.Este puente, recientemente construido, sobre el Rin, tiene una longitud total de 524 m, es de hormigón armado y se ha realizado por el procedimiento de voladizos sucesivos, sin entramado auxiliar ni cimbras. La luz del tramo central es de 208 m, y las de los otros seis oscilan entre 43 y 71 m. La estructura del tablero se compone de dos partes independientes, formadas por una viga tipo cajón, continua, con una articulación en la clave del tramo central y rigidizada con diafragmas transversales espaciados a 34 m. Las pilas centrales se apoyan sobre cajones neumáticos que descienden 16 m debajo del fondo del río. La unión entre estas pilas y la estructura cajón es rígida, y de tipo rodillo en las otras pilas. El tramo central se ha construido por voladizos

  6. Algunas reflexiones sobre el poder itinerante almohade.

    Directory of Open Access Journals (Sweden)

    Maribel FIERRO

    2009-12-01

    Full Text Available La primera parte del artículo consiste en la presentación de dos estudios sobre el poder itinerante en el Magreb: Jocelyne Dakhlia (1988 para las épocas hafsí y posteriores; Manuela Marín (2005 sobre el caso almohade. En la segunda parte, primeramente se analiza la convergencia del itinerario de Ibn Tumart con las conquistas de ‘Abd al-Mu’min: el movimiento –real o legendario– del fundador mesiánico del imperio marca el territorio conquistado por su sucesor el califa y su presencia inserta el espacio en la memoria, la geografía y el poder imperiales. A continuación, se plantea la compleja cuestión de la «capitalidad» almohade: se puede hablar de una capital sagrada (Tinmal, una capital central (Marrakech, capitales regionales (Sevilla, Túnez y de una nueva capital inacabada (Rabat. Pero es la presencia (hadar del propio califa la que determina dónde está el centro del imperio.La première partie de cet article présente deux études sur le pouvoir itinérant au Mahgreb : celle de Jocelyne Dakhlia (1986 sur la période hafside et les suivantes, celle de Manuela Marín (2005 sur le cas almohade.Dans la seconde partie, on analyse d’abord la convergence de l’itinéraire d’Ibn Tumart avec les conquêtes d’‘Abd al-Mu’min : le  trajet – réel ou légendaire – du fondateur messianique de l’empire marque le territoire conquis par son successeur le calife et sa présence ancre l’espace dans la mémoire, la géographie et le pouvoir impériaux. Ensuite, on examine la question complexe de la « capitalité » almohade : on peut parler d’une capitale sacrée (Tinmal, d’une capitale centrale (Marrakech, de capitales régionales (Séville, Tunis et d’une nouvelle capitale inachevée (Rabat. Mais c’est la présence (hadar du calife lui-même qui détermine où est le centre de l’empire.

  7. Sobre la rehabilitación de la arquitectura

    OpenAIRE

    Iglesia Salgado, Félix de la

    2012-01-01

    El presente ensayo reflexiona sobre el papel actual de la técnica de la arquitectura ante determinadas estrategias y comportamientos urbanos que, volcadas sobre nuevas situaciones resultado del cambio cualitativo y cuantitativo que se produce en nuestras ciudades, proponen una nueva urbanidad; una búsqueda, a partir de la rehabilitación del tejido residencial y los espacios de relación, sobre el control de los nuevos lugares y formas de habitabilidad que se hacen visibles como partes de una r...

  8. Pilas de arena sobre grafos dirigidos y algo de complejidad

    Directory of Open Access Journals (Sweden)

    Carolina Mejía Moreno

    2006-01-01

    Full Text Available En este artículo estudiamos el Modelo de Pilas de Arena sobre grafos dirigidos. El comportamiento del modelo sobre grafos dirigidos es más complejo (en término estrictos que sobre grafos no dirigidos; es por ello que, para muchas de las preguntas centrales de la teoría, no se conoce la respuesta en el caso dirigido. En este artículo se ha sintetizado la teoría para digrafos, se han simplificado algunas pruebas y se concretan algunos resultados relacionados con la complejidad de predicción del autómata.

  9. Pistas para pensar las significaciones imaginarias sobre la invariancia

    OpenAIRE

    Bilyk, Pablo Andrés

    2011-01-01

    Este escrito propone un primer esbozo de nominalizaciones sobre las significaciones imaginarias en torno a la idea de invariancia, con el fin de comenzar a mapear categorías para transitar que nos permitan pensar las construcciones fantasmáticas sobre el no-cambio. En definitiva, se trata de avanzar sobre la problematización de los modos de funcionamiento, constitución y reconfiguraciones de las hegemonías en los entramados sociales contemporáneos.

  10. Sobre a "conveniência" da escola

    Directory of Open Access Journals (Sweden)

    Marisa Vorraber Costa

    2009-01-01

    Full Text Available El artículo pretende mostrar un nuevo "uso" para la escuela, vinculado a la lógica de la etapa actual de la globalización en la que la cultura ocupa una posición singularmente importante, entrelazándose en la vida social, en los circuitos económicos y en los regímenes políticos. Recurriendo a la teorización de George Yúdice sobre los usos de la cultura en la era global, se analizan tres proyectos sociales - Você Apita, Tim Música nas Escolas y Escola Aberta - considerados expresivos de la forma como empresas, organizaciones públicas e iniciativas de la sociedad civil se articulan con la cultura y con la educación para hacer con que los mercados globalizados se muevan, pero no sólo en sus propios intereses, aunque ellos persistan en la cima de las prioridades. Hay indicios de que la "conveniencia" de la escuela sobrepasa el interés mercantil inmediato, y se proyecta como estrategia dirigida hacia una variada gama de propósitos socio-políticos, económicos y culturales. Entre ellos, la posibilidad de gobernar la vida de las personas, forjando visiones de mundo y de sociedad.

  11. sobre la población

    Directory of Open Access Journals (Sweden)

    Mauricio Schoijet

    2005-01-01

    Full Text Available En este artículo se analizan varios elementos de la obra de Thomas Malthus sobre población, en particular la recepción de su teoría y su posición política. Se resumen las críticas políticas, ideológicas y científicas que ha recibido, y se examinan asuntos hasta ahora no tratados por otros comentaristas, como es el caso de las excepciones admitidas por Malthus respecto al papel de las relaciones sociales feudales en la agricultura de Polonia y Rusia. Se sugiere que pese a que su teoría tendía a reforzar la pesada represión social y sexual existente, Malthus no fue apoyado por la burguesía británica (contrariamente a la apreciación de Marx. Se deduce que Malthus no percibió cabalmente los avances de la agricultura, y se refuta la tesis de Donald Winch de que habría sido un liberal de izquierda en política pues si bien en algunos aspectos se le puede considerar progresista, en otros, esenciales, conservador extremadamente represivo o protofascista, incluso precursor de la teoría de los golpes de Estado.

  12. Consideraciones sobre de la ética

    Directory of Open Access Journals (Sweden)

    Enrique Cantolla Bernal

    2005-12-01

    Full Text Available El presente ensayo muestra como el hombre, a través de la historia, a estado constantemente buscando beneficios para su vida y ha debido cumplir con varias tareas, que con el tiempo han dado origen a costumbres y comportamientos que han llevado a constituir la moral y la ética. Esta última, nos permite definir y determinar los principales fines de la vida del hombre y cuales son los principios y normas que lo rigen. Así, el estudio de la ética nos plantea la interrogante sobre "los fines de la vida en este mundo" y cuales son las conductas para conseguirlos. Sin embargo, el autor plantea que el hombre se enfrenta a la elección de valores alternativos y ante la interrogante de ¿cuál es el sumo bien del ser humano y de la sociedad?, han surgido diversas teorías que muestran como, casi todas las sociedades, han elegido la búsqueda de la felicidad como "el sumo bien", pero este concepto de "la felicidad" ha variando producto de las diversas teorías y doctrinas, que han emergido a lo largo de su historia.

  13. Apuntes sobre el Cultivo del Cacao

    Directory of Open Access Journals (Sweden)

    Chavarriaga. Eduardo

    1940-09-01

    Full Text Available El sombrío constituye uno de los problemas que se presentan en el cultivo del cacao, de necesaria resolución para ayuda del agricultor en su labor al producir tan importante grano. Contribuye a la economía del cultivo un conocimiento amplio de la cuestión que debe preocupar al productor inquiriendo no solamente por lo acostumbrado en la región, sino por lo que en otras partes se conoce sobre el particular, para abandonar un poco el emperismo y hacer una industria cada día más próspera. Como razón a favor del sombrío, tenemos los países en donde se produce cacao de fina calidad; Trinidad, Venezuela. Nicaragua, siempre acostumbran la sombra; y sin ir muy lejos, en el Valle del Cauca, donde no se cultiva a pleno sol y se obtienen plantaciones de larga duración y producto superior, es bien conocido el beneficio de ella; allí, los agricultores conocen los desastrosos efectos que ocasiona la falta de sombra, cuando por cualquier causa mueren los árboles que la suministran. Por tanto, en este estudio indicaremos el uso de la sombra para el cacao, como el medio de conservar la fertilidad y buenas condiciones del suelo, obtener buenos rendimientos y asegurar larga vida a la plantación.

  14. NOTAS SOBRE A IRRACIONALIDADE DA GUERRA

    Directory of Open Access Journals (Sweden)

    Edilene Leal

    2014-08-01

    Full Text Available Nesse artigo, procedemos a uma análise sobre a irracionalidade da guerra em tempos cada vez mais caracterizados pela evolução da racionalidade técnica, ou seja, em tempos contemporâneos. Esse é o ponto a partir do qual traçamos, aqui, um percurso argumentativo dividido em duas partes. Na primeira, reconstituímos elementos da concepção de guerra de filósofos como Maquiavel, Clausewitz e Kant, destacando, nos dois primeiros pensadores, a prerrogativa de que a guerra é racional quando se configura meio para fins políticos. Na segunda parte, confrontamos essa racionalidade política da guerra com a dupla dimensão técnica que a guerra assumiu: de um lado, a guerra como um fim em si mesmo e não mais como meio da ação política; de outro, a dimensão racionalizante da guerra como resultado do progresso técnico e científico, atualizada como guerra do terror.

  15. Cassirer e Sartre sobre o esclarecimento

    Directory of Open Access Journals (Sweden)

    Vinicius de Figueiredo

    2005-12-01

    Full Text Available O presente ensaio levanta alguns aspectos da estética no século XVIII. Partindo da apresentação de duas interpretações hoje clássicas sobre o assunto (a de Cassirer e a de Sartre, busca rever o pressuposto analítico comum a ambas, para, em seguida, apontar as conseqüências que a relação entre autor e público trazem para a compreensão de aspectos estilísticos que nos parecem centrais para a literatura do Esclarecimento.This paper aims at throwing some light on the Eighteenth-Century aesthetics. After examining two classical interpretations - Cassirer e Sartre's - concerning this subject, I argue that both authors share a common analytical pressupposition. My main purpose is to show that without taking account of the the relationship between author and public, we cannot understand some essential characteristics of the literature in the Enlightenment.

  16. Fechas y sospechas sobre Lucas de Tuy

    Directory of Open Access Journals (Sweden)

    Linehan, Peter

    2002-06-01

    Full Text Available The present essay seeks to establish what we know, as opposed to what we think we know, about the author of the Chronicon Mundi. Amongst the issues investigated are those of don Lucas's origins, the nature of his connections with León, the date of his activity as chronicler, and the use which may have been made of that work by D. Rodrigo Jiménez de Rada in the De rebus Hispaniae.

    El presente estudio busca establecer qué es lo que sabemos, en oposición a qué es lo que pensamos que sabemos, sobre el autor del Chronicon mundi. Entre los aspectos investigados están los orígenes de don Lucas de Tuy, la naturaleza de sus conexiones con León, la datación de su actividad como cronista así como el uso que pudiera haber hecho Rodrigo Jiménez de Rada de su obra en el De rebus Hispaniae.

  17. BTG/Tob family members Tob1 and Tob2 inhibit proliferation of mouse embryonic stem cells via Id3 mRNA degradation

    International Nuclear Information System (INIS)

    The mammalian BTG/Tob family is a group of proteins with anti-proliferative ability, and there are six members including BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. Among them, Tob subfamily members, specifically Tob1/Tob and Tob2, have the most extensive C-terminal regions. As previously reported, overexpression of BTG/Tob proteins is associated with the inhibition of G1 to S-phase cell cycle progression and decreased cell proliferation in a variety of cell types. Tob subfamily proteins have similar anti-proliferative effects on cell cycle progression in cultured tumor cells. An important unresolved question is whether or not they have function in rapidly proliferating cells, such as embryonic stem cells (ESCs). Tob1 and Tob2 were expressed ubiquitously in mouse ESCs (mESCs), suggesting a possible role in early embryonic development and mESCs. To address the above question and explore the possible functions of the Tob subfamily in ESCs, we established ESCs from different genotypic knockout inner cell mass (ICM). We found that Tob1−/−, Tob2−/−, and Tob1/2 double knockout (DKO, Tob1−/− & Tob2−/−) ESCs grew faster than wild type (WT) ESCs without losing pluripotency, and we provide a possible mechanistic explanation for these observations: Tob1 and Tob2 inhibit the cell cycle via degradation of Id3 mRNA, which is a set of directly targeted genes of BMP4 signaling in mESCs that play critical roles in the maintenance of ESC properties. Together, our data suggest that BTG/Tob family protein Tob1 and Tob2 regulation cell proliferation does not compromise the basic properties of mESCs. - Highlights: • We established mouse Tob1/2 double knockout embryonic stem cells. • Tob1 and Tob2 inhibit the proliferation of ESCs without effect on pluripotency. • Tob1 and Tob2 involved in the degradation of Id3 in mESCs

  18. Elastic relaxations associated with the Pm3m-R3c transition in LaA103 III: superattenuation of acoustic resonances

    Energy Technology Data Exchange (ETDEWEB)

    Darling, Timothy W [Los Alamos National Laboratory; Carpenter, M A [UNIV OF CAMBRIDGE; Buckley, A [UNIV OF CAMBRIDGE; Taylor, P A [UNIV OF CAMBRIDGE; Mcknight, R E A [UNIV OF CAMBRIDGE

    2009-01-01

    Resonant Ultrasound Spectroscopy has been used to characterize elastic softening and a variety of new acoustic dissipation processes associated with the Pm{bar 3}m {leftrightarrow} R{bar 3}c transition in single crystal and ceramic samples of LaAlO{sub 3}. Softening of the cubic structure ahead of the transition point is not accompanied by an increase in dissipation but follows different temperature dependences for the bulk modulus, 1/3(C{sub 11} + 2C{sub 12}), and the shear components 1/2(C{sub 11}-C{sub 12}) and C{sub 44} as if the tilting instability contains two slightly different critical temperatures. The transition itself is marked by the complete disappearance of resonance peaks (superattenuation), which then reappear below {approx}700 K in spectra from single crystals. Comparison with low frequency, high stress data from the literature indicate that the dissipation is not due to macroscopic displacement of needle twins. An alternative mechanism, local bowing of twin walls under low dynamic stress, is proposed. Pinning of the walls with respect to this displacement process occurs below {approx}350 K. Anelasticity maps, analogous to plastic deformation mechanism maps, are proposed to display dispersion relations and temperature/frequency/stress fields for different twin wall related dissipation mechanisms. An additional dissipation process, with an activation energy of 43 {+-} 6 kJ.mole{sup -1}, occurs in the vicinity of 250 K. The mechanism for this is not known, but it is associated with C{sub 44} and therefore appears to be related in some way to the cubic {leftrightarrow} rhombohedral transition at {approx}817 K. Slight softening in the temperature interval {approx}220 {yields} 70 K of resonance peaks determined by shear elastic constants hints at an incipient E{sub g} ferroelastic instability in LaAlO{sub 3}. The softening interval ends with a further dissipation peak at {approx} 60 K, the origin of which is discussed in terms of freezing of atomic

  19. The central dynamics of M3, M13, and M92: stringent limits on the masses of intermediate-mass black holes

    Science.gov (United States)

    Kamann, S.; Wisotzki, L.; Roth, M. M.; Gerssen, J.; Husser, T.-O.; Sandin, C.; Weilbacher, P.

    2014-06-01

    We used the PMAS integral field spectrograph to obtain large sets of radial velocities in the central regions of three northern Galactic globular clusters: M3, M13, and M92. By applying the novel technique of crowded field 3D spectroscopy, we measured radial velocities for about 80 stars within the central ~10″ of each cluster. These are by far the largest spectroscopic datasets obtained in the innermost parts of these clusters up to now. To obtain kinematical data across the whole extent of the clusters, we complement our data with measurements available in the literature. We combine our velocity measurements with surface brightness profiles to analyse the internal dynamics of each cluster using spherical Jeans models, and investigate whether our data provide evidence for an intermediate-mass black hole in any of the clusters. The surface brightness profiles reveal that all three clusters are consistent with a core profile, although shallow cusps cannot be excluded. We find that spherical Jeans models with a constant mass-to-light ratio provide a good overall representation of the kinematical data. A massive black hole is required in none of the three clusters to explain the observed kinematics. Our 1σ (3σ) upper limits are 5300 M⊙ (12 000 M⊙) for M3, 8600 M⊙ (13 000 M⊙) for M13, and 980 M⊙ (2700 M⊙) for M92. A puzzling circumstance is the existence of several potential high velocity stars in M3 and M13, as their presence can account for the majority of the discrepancies that we find in our mass limits compared to M92. Based on observations collected at the Centro Astronómico Hispano-Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Appendices are available in electronic form at http://www.aanda.orgTables D.1 to D.6 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc

  20. BTG/Tob family members Tob1 and Tob2 inhibit proliferation of mouse embryonic stem cells via Id3 mRNA degradation

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yuanfan; Wang, Chenchen [Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191 (China); Peking University Stem Cell Research Center, China National Center for International Research, Peking University Health Science Center, Beijing 100191 (China); SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, University of Chinese Academy of Sciences, Shanghai 200120 (China); Wu, Jenny [SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, University of Chinese Academy of Sciences, Shanghai 200120 (China); Li, Lingsong, E-mail: lils@sari.ac.cn [Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191 (China); Peking University Stem Cell Research Center, China National Center for International Research, Peking University Health Science Center, Beijing 100191 (China); SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, University of Chinese Academy of Sciences, Shanghai 200120 (China)

    2015-07-03

    The mammalian BTG/Tob family is a group of proteins with anti-proliferative ability, and there are six members including BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. Among them, Tob subfamily members, specifically Tob1/Tob and Tob2, have the most extensive C-terminal regions. As previously reported, overexpression of BTG/Tob proteins is associated with the inhibition of G1 to S-phase cell cycle progression and decreased cell proliferation in a variety of cell types. Tob subfamily proteins have similar anti-proliferative effects on cell cycle progression in cultured tumor cells. An important unresolved question is whether or not they have function in rapidly proliferating cells, such as embryonic stem cells (ESCs). Tob1 and Tob2 were expressed ubiquitously in mouse ESCs (mESCs), suggesting a possible role in early embryonic development and mESCs. To address the above question and explore the possible functions of the Tob subfamily in ESCs, we established ESCs from different genotypic knockout inner cell mass (ICM). We found that Tob1{sup −/−}, Tob2{sup −/−}, and Tob1/2 double knockout (DKO, Tob1{sup −/−} & Tob2{sup −/−}) ESCs grew faster than wild type (WT) ESCs without losing pluripotency, and we provide a possible mechanistic explanation for these observations: Tob1 and Tob2 inhibit the cell cycle via degradation of Id3 mRNA, which is a set of directly targeted genes of BMP4 signaling in mESCs that play critical roles in the maintenance of ESC properties. Together, our data suggest that BTG/Tob family protein Tob1 and Tob2 regulation cell proliferation does not compromise the basic properties of mESCs. - Highlights: • We established mouse Tob1/2 double knockout embryonic stem cells. • Tob1 and Tob2 inhibit the proliferation of ESCs without effect on pluripotency. • Tob1 and Tob2 involved in the degradation of Id3 in mESCs.

  1. Consideraciones sobre diferentes procesos productivos y sus consecuencias sobre el medio ambiente

    Directory of Open Access Journals (Sweden)

    Caridad Ramos Alvariño

    2004-01-01

    Full Text Available En el presente trabajo se exponen algunas consideraciones sobre diferentes procesos productivos y sus consecuencias sobre el medio ambiente. La disminución del impacto negativo de algunas producciones sobre el medio ambiente es favorable, pero el problema va más allá y de lo que se trata es de la necesidad de una transformación sostenible de las producciones que puedan conducir a una vida agradable y una naturaleza conservada entre otras muchas cuestiones que agobian hoy al mundo. La solución al problema puede ser alcanzada con mayor prioridad en la reducci ón de la fuente primaria de la contaminación, seguida por el reciclaje y el desarrollo de tecnologías limpias. La reducción en la fuente se aplica por los cambios de productos y procesos. El cambio de la fuente se relaciona con la composición o el uso de los productos intermedios y finales, que reduzcan los residuos de producción, su uso o la disposición de los productos. Los cambios de procesos están relacionados con la sustitución de las materias primas de entrada, la modificación de las tecnologías y las mejoras operacionales. Las opciones específicas pueden incluir: el uso de materiales menos tóxicos, el aumento de la automatización, los procedimientos para las operaciones y el mantenimiento, el control de inventario, entre otros.

  2. 氧气治疗3M透明敷料致皮肤过敏患儿的效果观察%Effect of oxygen therapy 3 M transparent dressings cause skin allergies in children

    Institute of Scientific and Technical Information of China (English)

    杨慧; 王金叶; 黄青

    2015-01-01

    Objective:To evaluate the effect of the blow - by oxygen therapy on skin allergy caused by 3 M transparent dressing. Methods:From August 2010 - August 2014 in our hospital due to the use of 3 M transparent dressings cause skin allergies in children 46 cases,the August 2010 - December 2012 occurred 3 M transparent dressings allergy 23 patients as the control group,conventional topical applicator every 4 h 1 time nursing,the January 2013 - Au-gust 2014 3 M transparent dressings occurred 23 cases of children with allergies as the observation group on the basis of conventional topical 4 h 1 time ap-plicator care on the use of oxygen therapy,observed the changes in the two groups of children with skin reactions,rash regression. Results:The clinical effica-cy of children in the observation group was better than the control group(P ﹤ 0. 05). Conclusion:The home oxygen therapy 3 M transparent dressings cause skin allergies effect is obvious,worthy of clinical application.%目的:探讨氧气治疗3 M 透明敷料所致过敏患儿的效果。方法:选取2010年8月~2014年8月我院因使用3 M 透明敷料致皮肤过敏患儿46例,将2010年8月~2012年12月发生3 M 透明敷料过敏的23例患儿作为对照组,常规局部每4 h 1次涂药护理,将2013年1月~2014年8月发生3 M 透明敷料过敏的23例患儿作为观察组,在常规局部4 h 1次涂药护理的基础上加用氧气疗法,观察两组患儿皮肤反应的变化、皮疹消退情况。结果:观察组患儿的临床疗效优于对照组(P ﹤0.05)。结论:加用氧气治疗3M 透明敷料致皮肤过敏效果明显,值得临床推广应用。

  3. Normativa sobre el impuesto sobre los gases efecto hivernadero (Green house gases tax)

    OpenAIRE

    Rodrigo de Larrucea, Jaime

    2013-01-01

    Como dice el apartado V de la Exposición de motivos de la Ley 16/2013, se crea un nuevo impuesto sobre los gases de efecto invernadero, relativo a los gases fluorados que se utilizan habitualmente en numerosos sectores como refrigerantes, disolventes, agentes espumantes o agentes extintores de incendios, para paliar de alguna manera su negativa contribución al calentamiento de la atmósfera, con un potencial de calentamiento global mucho más elevado que el CO2.

  4. Ação da melatonina sobre a dinâmica sanguínea de ratas prenhes e sobre a histogênese do baço e do timo da prole

    Directory of Open Access Journals (Sweden)

    A.C.C. Araújo

    2013-04-01

    Full Text Available Investigou-se a influência da melatonina sobre o hemograma de ratas prenhes e dos filhotes e sobre a histogênese e morfometria do baço e do timo dos filhotes. A melatonina foi administrada na dose 0,5mg/kg de peso corporal, dissolvida em 0,1mL de etanol e diluída em 0,3mL de solução salina. Para análise do hematócrito, contagem total de hemácias e contagem total e diferencial dos leucócitos, amostras de sangue foram coletadas no sétimo, 14ºe 21ºdias de prenhez e aos 10 dias de nascimento dos filhotes. Cortes histológicos do baço e do timo da prole foram utilizados para histoquímica e morfometria. A ausência da melatonina promoveu alterações no hemograma apenas no terço final da gestação, sem interferir no hemograma dos filhotes, e induziu modificações morfológicas e morfométricas no timo e no baço nos primeiros dias de vida dos filhotes. Concluiu-se que a melatonina materna é importante para a modulação do hemograma em ratas prenhes e para o desenvolvimento normal do baço e do timo dos filhotes.

  5. Algunas reflexiones acerca de la encuesta sobre trabajo colaborativo

    OpenAIRE

    Gargiulo, Sandra; Ponz, María Jimena

    2014-01-01

    Comenzamos el mes de noviembre con un nuevo tema del mes: Dinámicas de trabajo colaborativo virtual. Para ello, queremos compartir los resultados arrojados por la encuesta sobre el trabajo colaborativo que muchos de ustedes han completado.

  6. Reflexiones sobre el género y la censura

    OpenAIRE

    Daniel Cazés Menache

    2006-01-01

    Este trabajo analiza y reflexiona sobre la primera censura social: la censura genérica, es decir, la estructurada sobre la adscripción de género, arena en la que se sintetizan todas las censuras sociales destinadas a controlar a cada sujeto y a mantenerlo sometido a dominios de los que no podrá librarse ni para aceptarlos ni para ejercerlos.

  7. Banco Interamericano de Desarrollo informe sobre sostenibilidad 2011

    OpenAIRE

    Banco Interamericano de Desarrollo (BID)

    2012-01-01

    El Informe de Sostenibilidad contiene información sobre las contribuciones del BID a la sostenibilidad durante el año 2011. También proporciona información sobre las tendencias fundamentales del desarrollo y las dimensiones de sostenibilidad en América Latina y el Caribe. Este año, el informe se centra en la sostenibilidad y la agricultura en la región

  8. The expression levels of T -bet mRNA and GATA3 mRNA in peripheral blood of patients with preeclampsia%子痫前期患者外周血T - bet mRNA和GATA3mRNA的表达水平

    Institute of Scientific and Technical Information of China (English)

    李净; 杨海澜; 何银芳

    2011-01-01

    目的:从Th细胞特异性转录因子T- bet和GATA3的角度探讨其在子痫前期(pre - eclampsia)发病过程中可能的病理生理机制,为子痫前期的病因研究及免疫治疗提供思路.方法:采集正常产妇和子痫前期患者外周血单个核细胞(PBMCs),提取总RNA,逆转录成cDNA,利用SYBRGreenl荧光定量PCR方法,以β- actin为内对照基因检测每组PBMCs中T-bet mRNA和GATA3 mRNA的表达水平.结果:①GATA3 mRNA在正常妊娠组、子痫前期轻度组和子痫前期重度组的表达随病情的加重表达减弱,子痫前期重度组与正常妊娠组相比差异有统计学意义(P<0.05),子痫前期轻度组与正常妊娠组、子痫前期重度组比较差异无统计学意义(P>0.05);②T - bet mRNA的表达随病情的加重表达增强,子痫前期重度组与正常妊娠组、子痫前期轻度组相比差异有统计学意义(P<0.05),子痫前期轻度组的表达也高于正常妊娠组,但差异无统计学意义(P>0.05);③T - bet mRNA/GATA3 mRNA比值结果显示,随病情的加重比值增大,且子痫前期重度组与正常妊娠组比较差异有统计学意义(P<0.05),子痫前期轻度组与正常妊娠组、子痫前期重度组相比差异无统计学意义(P>0.05).结论:子痫前期患者外周血中表现为免疫杀伤的Th1型细胞转录因子T- bet mRNA表达增强,表现为免疫保护或免疫营养的Th2型细胞转录因子GATA3 mRNA表达减弱,提示子痫前期患者外周血中T- bet mRNA的高表达与其发病有关,GATA3 mRNA在子痫前期的发生、发展中的作用不如T - bet mRNA明显;T- bet mRNA/GATA3 mRNA比值随病情的加重而增大,提示外周血中Th1/Th2转录因子的平衡偏离可能是导致子痫前期发病的病因之一.%Objective: To explore the probable pathogenesis of preeclampsia from the point of T - bet and GATA3, provide ideas for etiological research and immune therapy of preeclampsia Methods: Mononuclear cells were obtained

  9. PROTOCOLO DE KYOTO: DEBATE SOBRE AMBIENTE Y DESARROLLO EN LAS DISCUSIONES SOBRE CAMBIO CLIMÁTICO

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    Rodríguez S. Liliana

    2008-07-01

    Full Text Available El comportamiento climático del planeta y sus consecuencias han propiciado debates sobre los modelos de desarrollo de los países responsables del deterioro acelerado del ambiente y de los fenómenos naturales por estos días recurrentes. Sin embargo, países como Estados Unidos, luego de firmar compromisos como la Convención sobre Cambio Climático, rehúsan adquirir las obligaciones del Protocolo de Kyoto, por temor a sufrir deterioro en sus economías. En este escenario, donde la nación responsable de la emisión de aproximadamente 36% de los gases efecto invernadero resultado de la acción humana en el planeta no se compromete a adoptar políticas restrictivas tendientes a hacer sus modelos de producción más amigables con la naturaleza a pesar de que dichas medidas empiezan a ser impuestas a otras naciones como condicionantes en las negociaciones comerciales internacionales, parece ser que la adopción del Protocolo de Kyoto para países en desarrollo como Colombia no es del todo benéfica.

  10. EFEITO DE CALDAS SOBRE Corynespora cassiicola

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    Mercia Celoto

    2014-11-01

    Full Text Available The target spot (Corynespora cassiicola, main leaf disease occurred in barbados cherry in the regionof Junqueirópolis, SP, causing severe defoliates of plants. After the cleaning prune, producers apply line sulfhur in plants, for presenting fungicidal, insecticide and acaricide action. The objective of this study was to assess the effect of line sulfhur (75% and 3% - used by producers, bordeaux mixture (75% and „calda Viçosa‟ (75% on Corynespora cassiicola. The syrups were incorporate into potato-dextrose-agar or spore suspension for determination of inhibition of the mycelia growth and spores germination. Leaves barbados cherry, with symptoms of target spot, were treated with syrups. In wet champer, high humidity, was verified that sporulation occured in lesions, however the spores lost viability by presence of syrups in surface. In vitro, line sulfhur to 75% inhibited completely the mycelia growth of the fungus. Line sulfhur, Bordeaux mixture and „calda Viçosa‟ inhibited completely the spores germination. For the reasons, the use of syrups in barbados cherry, can contribute in reduction of souce of inoculum of the pathogen. A mancha alvo (Corynespora cassiicola é a principal doença da cultura da acerola, na região de Junqueirópolis, SP, causando desfolha precoce nas plantas. Após a realização da poda de limpeza anual, os produtores aplicam a calda sulfocálcica nas plantas, por apresentar ação fungicida, inseticida e acaricida. O objetivo deste trabalho foi avaliar em condições in vitro e in vivo o efeito das caldas sulfocálcica, bordalesa e Viçosa sobre Corynespora cassiicola. As caldas foram utilizadas nas seguintes concentrações: calda sulfocálcica (75 e 3% - concentração utilizada por produtores, calda Bordalesa (75% e calda Viçosa (75%. As caldas foram incorporadas em meio de batata-dextrose-ágar ou suspensão de esporos para determinação das inibições do crescimento micelial e da germinação de esporos

  11. Sobre o campo da Psicologia Social

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    Belinda Mandelbaum

    2012-03-01

    Full Text Available O campo da Psicologia Social é apresentado como território fértil, na contemporaneidade, para constituir-se como um laboratório para a produção em Ciências Humanas, uma vez que, no século XX, cada vez mais o social foi em direção ao psicológico. Neste campo, nosso embate dá-se no modo como entendemos o hífen pressuposto na integração psicossocial. A autora propõe que, entre o psicológico e o social, o hífen domina, pois ele é a própria essência relacional que é inerente a cada um dos elementos. Sugere que o modelo para entender o homem e suas circunstâncias proposto por Freud imbrica de forma indissociável o psicológico e o social, a ontogênese e a filogênese, com uma potência que teve impacto sobre todo o campo das Ciências Humanas. A Psicanálise é um instrumento hermenêutico para colaborar na elucidação dos fenômenos sociais. A autora utiliza imagens construídas por Freud e Walter Benjamin e poemas de Carlos Drummond de Andrade para fortalecer o entendimento do hífen psicossocial tanto em sua ação multidimensional quanto em sua organização.

  12. Construcciones en yeso proyectado sobre vegetales

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    Martínez, Hubert

    1986-07-01

    Full Text Available A construction method developed in early 1981 in Senegal, whose main objective is the evaluation of natural and human sources, specially those of wild vegetables and the phosphogypsum (a waste of chemical industry in Senegal. The introduction of the mechanical projection allows a noticeably growth in work performances and an improvement of the quality. The projection reduces de number of trades intervening in the work, doing away with plasters, watertightness systems and paintings, and simplifying the setting of technical installations and of carpentry. The acquisition of this projecting material is not very expensive, so, it is easy for small and medium enterprises to reach an expertness in gypsum work. Its finantial rentability is assured for a prize of the gypsum of 180% of the prize of the cement.Procedimiento de construcción desarrollado al comienzo de 1981 en el Senegal, teniendo como objetivo la valoración de las fuentes naturales y humanas, especialmente los vegetales en estado silvestre y el fosfoyeso, residuo de la industria química del Senegal. La introducción de la proyección mecánica permite aumentar sensiblemente el rendimiento del trabajo y mejorar la calidad. La proyección reduce el número de oficios que intervienen en la obra por la supresión de enlucidos, sistemas de estanquidad y pinturas sobre la gruesa obra y simplifica la colocación de las instalaciones técnicas y de carpintería. La adquisición del material de proyección, necesitando un capital relativamente modesto, se encuentra al alcance de pequeñas y medianas empresas que deseen especializarse en los trabajos de yeso. La rentabilidad financiera del procedimiento está asegurada para un precio del yeso de hasta el 180% del precio del cemento.

  13. Puente sobre el Rhin – Suiza

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    Bänziger, D. J.

    1972-10-01

    Full Text Available In the brief period of two months a new bridge over the Rhine has been constructed to substitute one which collapsed on August 1970, because of the undermining of one of its pillars. On November 28 1970 the new bridge was opened to the traffic, including trucks of up to 3.5 Kp, and on December 7th of the same year vehicles of up to 26 Kp could use it. In the construction of this bridge, for the first time, use has been made of cylindrical, prefabricated, precast thin shells. This project is of special significance because of its operational importance, since it connects Lichtenstein and Switzerland; the exceptionally short time of its construction; and the new type of deck used.Para sustituir un puente sobre el Rhin, hundido el 14 de agosto de 1970 por socavación de uno de sus pilares, se ha construido un nuevo puente en el escaso plazo de dos meses. El 28 de noviembre de 1970, este nuevo puente se abrió al tráfico de vehículos de hasta 3,5 Mp, y el 7 de diciembre del mismo año, a los vehículos de hasta 26 Mp. En la construcción de este puente se han utilizado, por vez primera, láminas cilíndricas de cubierta, prefabricadas y pretensadas. La importancia del puente, que sirve para el enlace entre el Principado de Liechtenstein y Suiza, el nuevo tipo de tablero utilizado, así como el plazo de construcción, extraordinariamente breve, dan un interés especial a esta obra.

  14. Perspectivas sobre la comunicación

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    María Luisa Naranjo Pereira

    2005-01-01

    Full Text Available Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la relación humana y en las etapas donde se desarrolla. A partir de la comunicación pragmática, se analizan los axiomas comunicacionales en que se fundamenta y lo que se conoce como patologías de esos axiomas. Además se revisan las principales características que distinguen la asertividad en la comunicación y las distintas formas de manipulación que la entorpecen. Del enfoque de Virginia Satir, se presentan los diversos aspectos de la comunicación, tanto funcional como disfuncional y los modelos de comunicación propuestos por esta autora. Se revisan aspectos importantes del enfoque de la comunicación educativa, tales como el control de la distancia, la voz y el cuerpo, las palabras y el situacional; así como los elementos que bloquean el proceso de comunicación y las sugerencias acerca de formas correctas de escuchar. Además, se hace referencia a la necesidad de emplear procesos educativos más holísticos y constructivistas y una comunicación-interrelación horizontal y con equidad.

  15. Sobre el genio de las mujeres

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    Valcárcel, Amelia

    1992-11-01

    Full Text Available Not available.

    A los varones, desde Tácito a Schopenhauer, nunca les ha parecido que las verdaderas mujeres son las que tienen en casa, sino las que tienen los otros varones (los germanos, los orientales. Por su parte, Wojtyla ha hecho profesión de fe «en el genio de las mujeres», reclutando enternecidos agradecimientos como el de Macciochi. La autora del presente artículo adopta una perspectiva histórica y una actitud analítica para aclarar qué es ese genio que como genérico nos adjudican. En primer lugar, la idea de genio es romántica y va emparejada con la de destino, sobre todo en el caso de los genios colectivos. Se trata de nociones que se construyen estipulativamente con fines pragmáticos y no admiten, por definición, contraejemplos. En el caso del genio de las mujeres, los llamados «valores femeninos» que lo constituyen pertenecen al ámbito de la Siulichkeit, y su eventual convalidación en el de la Moralitiit no puede obviar el proceso consistente en la crítica y el desmarcarse de una Sittlichkeit adjudicada como estereotipia que se contrasta, no con otra estereotipia simétrica, sino con lo universal, que se solapa con el genérico masculino. La autora, por último, nos recuerda que la fabricación de este genio que, a título de colectivo, se nos atribuye a las mujeres tiene lugar a costa de la usurpación de nuestra individualidad y de la ausencia de esquemas pragmáticos de reconocimiento de la genialidad individual que pueda producirse en el genérico femenino. Ahora bien: es esta última la que las mujeres necesitamos para poder romper con las tradiciones establecidas e instituir nuevos relatos.

  16. Estudio sobre encofrados de madera modernos

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    de la Peña Aznar, Juan M.

    1980-12-01

    Full Text Available The author continues the development of the subject «Modern Timber Formwork», by summing up the comparative examination —already carried out in Part III of this Study— of the different types of glued timber existing on the market. In addition, the loads and stresses allovk/able for coniferous timber and the proposal for establishing Regulations for the Timber Section of the Research and Experimental Forestry Institute of Spain are given. In part V of the author's Study, published in this article, the important subject of the glues used for joining timber, a truly vital point in order to obtain louvered timber beams which are simply glued together, is approached.

    El autor continúa el desarrollo del tema sobre «Encofrados de madera modernos», resumiendo el estudio comparativo —ya hecho en la Parte III de este Estudio— de las diferentes vigas de madera encolada existentes en el mercado dando, además, las cargas y tensiones admisibles para maderas coníferas y la propuesta de Reglamentación de la Sección de Maderas del Instituto Forestal de Investigaciones y Experiencias de España. En la parte V del Estudio del autor, publicada en este artículo, se aborda el importante tema de las colas empleadas para las uniones de madera, algo realmente vital para la obtención de vigas de madera en celosía simplemente encoladas.

  17. Estudos sobre a Esquistosomose em Pernambuco, Brasil

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    Aggeu Magalhães

    1940-01-01

    Full Text Available Os autores referem os resultados dos estudos sobre esquistosomose realisados, em Pernambuco, de Novembro de 1938 a Dezembro de 1939. Não se extendem em discussão, nem comentarios, tampouco, relacionam suas verificações com o que já foi relatado sobre o assunto em trabalhos nacionais e estrangeiros, pelo fato de que, não se trata de um resultado definitivo e sim de atividades que irão proseguir. Os estudos sistematicos em torno da endemia esquistosomica foram executados em duas localidades diversas pela população e pela situação geografica e ecologica. Pontezinha é uma povoação de 1200 habitantes localizada proximo a um conjunto de charcos e lagõas de agua dôce onde pululam caramujos do tipo olivaceus de Spix, e apresenta uma taxa de infestação de 21,4% para individuos do sexo masculino, e de 14,7% para os do sexo feminino. A distribuição por grupos de idade mostra que a incidencia cresce até o grupo de 16 a 20 anos de idade, quando atinge a percentagem de 37,8%, para decrescer em seguida. Em Vitoria a incidencia foi maior nos indivíduos do sexo feminino, atingindo a taxa de 41,4%, dando o sexo masculino a taxa de 36,9%. Por idade a percentagem maxima é atingida pelo grupo de 11 a 15 anos. Vitoria é uma cidade de 1500 habitantes, construida á margem do rio Tapacurá, onde se encontram numerosos caramujos do tipo centimetralis Lutz. A divergencia de incidencia corre por conta dos habitos da população e pela utilização que ela faz do rio, sendo maior em Vitoria porque a proximidade do rio facilita o uso de suas aguas para banho e serviços domesticos, condicionando este ultimo fato, a maior infestação das mulheres. O estudo da frequencia da infestação dos caramujos por cercarias de diversos trematodios, permite suspeitar uma relação inversa entre a taxa de infestação e o diametro maximo atingido pelos caramujos, parecendo este fato confirmar os trabalhos de Vianna Martins sobre a identidade dos hospedeiros

  18. Abrogation of heat-shock protein (HSP)70 expression induced cell growth inhibition and apoptosis in human androgen-independent prostate cancer cell line PC-3m

    Institute of Scientific and Technical Information of China (English)

    Zhi-GangZhao; Qing-ZhengMa; Chun-XiaoXu

    2004-01-01

    Aim: To investigate the effect of abrogating heat shock protein (HSP) 70 expression by antisense HSP70 oligonucleotides treatment on human androgen-independent prostate cancer cell line PC-3m growth. Methods: PC3m cells were treated with 0-16μmol/L antisense HSP70 oligomers for 0-100 hr. Cell growth inhibition was analyzed using a trypan blue dye exclusion test. Apoptotic cells were detected and confirmed by flow cytometric analysis and DNA fragmentation analysis. The protein expression of HSP70 and bcl-2 affected by antisense HSP70 oligomers were determined using Western blot. Results: Antisense HSP70 oligomer induced apoptosis and then inhibited proliferation of PC-3m cells in a dose- and time-dependent manner. Ladder-like patterns of DNA fragments were observed in PC-3m cells treated with 10μmol/L antisense HSP70 oligomer for 48 hr or 8μtmol/L for 72 hr on agarose gel electrophoresis. Antisense HSP70 oligomer pretreatment enhanced the subsequent induction of apoptosis by heat shock in PC-3m cells. In addition, undetectable HSP70 expression was observed at a concentration of 10μtmol/L antisense HSP70 oligomer treatment for 48 hr or 8μtmol/L for 72 hr in Western blot, which was paralleled by decreased expression levels of anti-apoptotic protein bcl-2. Conclusion: HSP70 antisense oligomer treatment abro-gates the expression of HSP70, which may disrupt HSP70-bcl-2-interactions and further down-regulate bcl-2 expression,in turn inducing apoptosis and inhibiting cell growth in PC-3m cells. (Asian JAndro12004 Dec;6:319-324)

  19. Dois estudos sobre o trabalho dos petroleiros

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    Leda Leal Ferreira

    1996-06-01

    Full Text Available O presente artigo traz um resumo de dois estudos realizados na área do petróleo, o primeiro feito em uma unidade de refino e o segundo abarcando o trabalho de operadores exercendo várias funções dentro de uma refinaria e de terminais marítimos de petróleo. Nos dois casos, o ponto central foi a análise da atividade dos trabalhadores, isto é, o que eles faziam e como o faziam para dai conta das exigências de produção que lhes eram atribuídas. No entanto, os métodos utilizados foram diferentes: no primeiro caso utilizou-se a Análise Ergonômica do Trabalho (AET e no segundo, a Análise Coletiva do Trabalho (ACT. Além de apresentar os principais resultados destes estudos, a autora faz considerações sobre as diferenças entre os dois métodos e um apelo à comunidade científica para que se preocupe mais em estudar a atividade real dos trabalhadores e assim contribuir para um melhor conhecimento do que se passa no interior das unidades produtivas, evitando que sofrimentos humanos inúteis e até catástrofes industriais continuem a ocorrer.This paper describes two studies about petroleum industry. The first was developed in a refinery and the second focuses on the work of operators in various jobs within a refinery and maritime petroleum units. In both cases, the focal point was the analyses of activities, that is, what the workers do and how they do it in order to meet production demandai put on them. However, two different methods were applied in the studies. Ergonomics Work Analyses (EWA was used on the first case and Collective Work Analyses (CWA, on the second. Besides showing the main results, the author compares the two methods. She also draws the scientific community attention to the importance of studding the workers actual activity in order to contribute to a better understanding of what is going on inside production units, avoiding useless human suffering, and the still ocurring undustrial disasters.

  20. Marginalia: algumas notas adicionais sobre o dom

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    Pierre Bourdieu

    1996-10-01

    Full Text Available Prosseguindo a análise do dom, este artigo busca ultrapassar as visões fenomenológica, estruturalista e economicista do fenômeno. Para tanto, desloca o eixo de interrogação na direção do tempo e da incerteza ligados ao intervalo entre o dom e o contradom, do agente e da ação ligados às práticas, da economia de bens simbólicos e o habitus específico que a funda. Demonstrase assim, contra todo reducionismo (à consciência, ao cálculo inconsciente ou ao cálculo propriamente dito, que a razão do dom só pode repousar sobre sua dupla verdade, seu caráter generoso e obrigatório. Por outro lado, demonstrase também que foi somente através de uma revolução simbólica, e não o desenvolvimento de uma suposta natureza humana, que uma economia da troca pôde, historicamente, se destacar da economia do dom, cuja possibilidade continua aberta, dependendo apenas dos investimentos coletivos que sejam efetuados em sua direção.Resuming an analysis of the gift, this article seeks to go beyond the phenomenological, structuralist, and economicist view of this phenomenon. It thereby shifts the trust of questioning towards the time and uncertainty linked with the interval between the gift and the counter-gift, the agent and the action linked to such practices, the economy of symbolic goods, and the specific habitus underlying it. It thus demonstrates against any and all reductionism (to consciousness, to unconcious calculation, and to calculation per se that the gift's reason can only lie in its double truth, its generous and obligatory nature, both disinterested and interested. The author also demonstrates historically that it is only through a symbolic revolution, and not the development of a supposed human nature, that an economy of exchange can stand out from the economy of the gift, whose possibility remains open, requiring collective investments in its direction.

  1. As vicissitudes do "ensaio sobre o dom"

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    Lygia Sigaud

    1999-10-01

    Full Text Available A partir dos anos 60, antropólogos de diferentes tradições nacionais passaram a convergir no sentido de considerar que o texto de Marcel Mauss, "Ensaio sobre o Dom", contivesse uma teoria da troca, que atribui à identificação entre a coisa dada e o espírito do doador o princípio de explicação das transações. Esta interpretação contrasta com a que tiveram os contemporâneos de Mauss, os quais resgataram do trabalho suas dimensões relativas ao direito, às obrigações e às prestações totais. Partindo desta constatação, o artigo problematiza o destino do ensaio e busca torná-lo inteligível. Para tanto examina as condições sociointelectuais que contribuíram para que se produzisse a inflexão na leitura e a consolidação de uma espécie de crença coletiva em relação ao trabalho. Através deste estudo de caso, a autora identifica mecanismos que operam no processo de construção de teorias, na conformação de representações acerca de textos e na sua consagração no âmbito da antropologia.From the 1960s, anthropologists of different national traditions came to share the view that Marcel Mauss’s text, "Essay on the Gift," contained a theory of exchange which takes the identification between the thing given and the spirit of the donor as the explanatory principle of transactions. This interpretation contrasts with that held by Mauss’s contemporaries, who lifted from the work aspects relating to law, obligations and total prestations. Starting from this fact, the article problematizes the essay’s fate and seeks to make it intelligible. To this end, it examines the socio-intellectual conditions which contributed to producing this inflection in the readings of the work and the consolidation of a kind of collective belief concerning it. Through this case study, the author identifies mechanisms which operate in the process of constructing theories, in the conformity found in representations of certain texts, and in the

  2. Measurement uncertainty evaluation of 3M PetrifilmTM aerobic count plate method for drinking water%生活饮用水3M PetrifilmTM菌落总数测试片法的不确定度评定

    Institute of Scientific and Technical Information of China (English)

    谭和平; 叶德萍; 沈兴中; 唐祥凯; 王智

    2012-01-01

    3M PetrifilmTM菌落总数测试片法检测生活饮用水中菌落总数的测量结果进行了不确定度评定,评述了引起测量结果不确定度的主要因素,对样品稀释及方法精密度因素进行了详细评价,并对单一样品重复测量10次及30个样品每个样品平行测量2次的两种情况,分别进行了重复性标准偏差评价.结果显示:单一样品重复测量时,测量结果的不确定度主要由样品稀释和重复性标准偏差引起,扩展不确定度U95为20 CFU/mL,k=2;多个样品每个样品平行测量2次时,测量结果的不确定度主要由重复性标准偏差引起,在95%的置信度时,扩展不确定度U(/lgxj)为0.093,k=2.75.%The aerobic plate count in drinking water was determined with 3M Petrifilm? Aerobic count plate, and their measurement uncertainties were evaluated in this study. Firstly, the main components of measurement uncertainty were discussed and analyzed. Then, two most important components, sample dilution and measurement precision were evaluated in detail. And for the precision, the authors evaluated two kinds of precision commonly used in routine work, the repeatability of 10 repeated measurements of single sample and those of double repeated measurements of thirty samples. Experimental results show the sample dilution affects the measurement uncertainty obviously for the case of single-sample test, and the standard deviation of repeated measurement is the most important source of uncertainty for that case and the case of multi -sample test. The expandeduncertainty f/95 was 20CFU/mL(A;=2) for the former case and the expanded uncertainty UilgXj ) was0.093 (k=2.75) for the latter when the degree of confidence is 95%.

  3. Plumbagin, a medicinal plant (Plumbago zeylanica) - derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model

    OpenAIRE

    Hafeez, Bilal Bin; Zhong, Weixiong; Fischer, Joseph W.; Mustafa, Ala; Shi, Xudong Daniel; Meske, Louise; Hong, Hao; Cai, Weibo; Havighurst, Thomas; Kim, KyungMann; Verma, Ajit K.

    2012-01-01

    We present here first time that Plumbagin (PL), a medicinal plant-derived 1,4-naphthoquinone, inhibits the growth and metastasis of prostate cancer (PCa) in an orthotopic xenograft mouse model. In this study, human PCa PC-3M-luciferase cells (2X106) were injected into the prostate of athymic nude mice. Three days post cell implantation, mice were treated with PL (2 mg/kg body wt. i.p five days in a week) for 8 weeks. Growth and metastasis of PC-3M-luciferase cells was examined weekly by biolu...

  4. Nota sobre Marcel Mauss e o ensaio sobre a dádiva

    Directory of Open Access Journals (Sweden)

    Lanna Marcos

    2000-01-01

    Full Text Available Este artigo analisa a obra clássica de M. Mauss, Ensaio sobre a dádiva, à luz de desenvolvimentos recentes da Antropologia. Salienta como contribuição de Mauss o entendimento da dimensão política da troca de dádivas, assim como a sugestão de sua universalidade, posteriormente demonstrada por Lévi-Strauss, constituir-se em princípio formal-abstrato, e não num fato empírico-concreto. A partir desse princípio, avalia a tese segundo a qual a dádiva é fundamento de toda sociabilidade e comunicação humanas, assim como sua presença e sua diferente institucionalização em várias sociedades analisadas por Mauss, capitalistas e não-capitalistas.

  5. Comentarios sobre la Ley de Ordenamiento Territorial Sostenible

    Directory of Open Access Journals (Sweden)

    Arturo J. Yglesias

    2014-04-01

    Full Text Available La denominada Ley de Ordenamiento Territorial Sostenible, no fue bien recibida en el medio jurídico. Tanto los profesores de las diferentes materias de Derecho de nuestra Facultad como las asociaciones profesionales y otros grupos e juristas de nuestro medio, formularon reservas de diverso calibre sobre el texto de la ley que van desde sus aspectos adjetivos como la terminología y redacción hasta cuestiones sustanciales como lo que ella dice sobre el régimen de la propiedad territorial y otras cuestiones vinculadas.Desde el discurso político vimos lanzar opiniones iracundas y alarmistas sobre las modificaciones que la ley estaría haciendo al régimen de la propiedad privada, sobre su supuesta inconstitucionalidad.Nosotros nos vamos a referir a la ley a sus antecedentes y de las críticas que se le hacían, en la parte que toca a nuestra materia, esto es en lo relativo al régimen de la propiedad y debemos decir, a vía de adelanto, que no vemos en ella nada que afecte el derecho de propiedad consagrado por la Constitución de la República, ni los principios generales que regulan la propiedad territorial conforme al Código Civil, conforme a la vieja ley de Centros Poblados, sus modificativas ni demás normas sobre la materia.

  6. 寻常性银屑病患者外周血白介素27、白介素35及EBI3 mRNA表达的研究%Expressions of interleukin-27,-35 and Epstein-Barr virus-induced gene 3 mRNA in peripheral blood of patients with psoriasis vulgaris

    Institute of Scientific and Technical Information of China (English)

    李姝文; 王秀敏; 李玉娟

    2013-01-01

    Objective To detect the expression of interleukin (IL)-27,-35 and their common subunit Epstein-Barr virus-induced gene 3 (EBI3) mRNA in peripheral blood from patients with psoriasis vulgaris (PV).Methods Peripheral blood was collected from patients with psoriasis vulgaris (PV) in progressive (n =22),stationary (n =20) and regressive (n =20) stage as well as 30 healthy human controls.A competitive enzymelinked immunosorbent assay (ELISA) was performed to determine the serum level of IL-27 and IL-35.SYBR Green-based real-time reverse transcription (RT)-PCR was carried out to measure the mRNA expression of EBI3 in peripheral blood mononuclear cells (PBMCs).Results The patients with psoriasis vulgaris showed a higher level of IL-27 and IL-35 compared with the healthy controls.The serum level of IL-27 was significantly higher in the patients with progressive,stationary and regressive psoriasis vulgaris than in the healthy human controls ((226.72 ±71.32) ng/L,(160.80 ± 20.02) ng/L and (181.93 ± 27.36) ng/L vs.(138.66 ± 33.93) ng/L,P< 0.01,0.05,0.01,respectively),and higher in the patients with progressive and regressive psoriasis vulgaris than in those with stationary psoriasis vulgaris (P < 0.01,0.05,respectively).Increased serum level of IL-35 was observed in the patients with regressive psoriasis compared with those with progressive and stationary psoriasis and healthy controls ((355.78 ± 49.82) ng/L vs.(309.36 ± 36.10) ng/L,(299.14 ± 31.98) ng/L and (292.43 ± 36.26) ng/L,all P < 0.01),while no statistical difference was observed between the patients with progressive and stationary psoriasos and healthy controls.The mRNA expression level of EBI3 in the patients with progressive,stationary and regressive psoriasis was 20.15,16.17 and 19.74 times,respectively,higher than that in the healthy controls.Conclusion IL-27,IL-35 and EBI3 may function as anti-inflammatory factors in the development,as well as the reversal of progression,of psoriasis.%目的 探

  7. Roles of vimentin and 14-3-3 zeta/delta in the inhibitory effects of heparin on PC-3M cell proliferation and B16-F10-luc-G5 cells metastasis

    Institute of Scientific and Technical Information of China (English)

    Yah PAN; Xue-jun LI; Li-jun ZHONG; Hong ZHOU; Xin WANG; Kui CHEN; Hao-peng YANG; Yilixiati XIAOKAITI; Aikebaier MAIMAITI; Ling JIANG

    2012-01-01

    Aim:To investigate the inhibitory effects of heparin on PC-3M cells proliferation in vitro and B16-F10-luc-G5 cells metastasis in Balb/c nude mice and identify the protein expression patterns to elucidate the action mechanism of heparin.Methods:Human prostate cancer PC-3M cells were incubated with heparin 0.5 to 125 μg/mL for 24 h.The proliferation of PC-3M ceils was assessed by MTS assay.BrdU incoporation and Ki67 expression were detected using a high content screening (HCS) assay.The cell cycle and apoptosis of PC-3M cells were tested by flow cytometry.B16-F10-luc-G5 cardinoma cells were injected into the lateral tail vein of 6-week old male Balb/c nude mice and heparin 30 mg/kg was administered iv 30 min before and 24 h after injection.The metasis of B16-F10-luc-G5 cells was detected by bioluminescence assay.Activated partial thromboplastin time (APTT) and hemorheological parameters were measured on d 14 after injection of B16-F10-luc-G5 carcinoma cells in Balb/c mice.The global protein changes in PC-3M cells and frozen lung tissues from mice burdened with B16-F10-luc-G5 cells were determined by 2-dimensional gel electrophoresis and image analysis.The protein expression of vimentin and 14-3-3 zeta/delta was measured by Western blot.The mRNA transcription of vimentin,transforming growth factor (TGF)-β,E-cadherin,and αv-integrin was measured by RT-PCR.Results:Heparin 25 and 125 μg/mL significantly inhibited the proliferation,arrested the cells in G1 phase,and suppressed BrdU incorporation and Ki67 expression in PC-3M cells compared with the model group.But it had no significant effect on apoptosis of PC-3M cells.Heparin 30 mg/kg markedly inhibits the metastasis of B16-F10-luc-G5 cells on day 8.Additionally,heparin administration maintained relatively normal red blood hematocrit but had no influence on APTT in nude mice burdened with B16-F10-luc-G5 cells.Thirty of down-regulated protein spots were identified after heparin treatment,many of which are related to

  8. Perspectivas sobre la comunicación

    Directory of Open Access Journals (Sweden)

    Naranjo Pereira, María Luisa

    2005-12-01

    Full Text Available Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la relación humana y en las etapas donde se desarrolla. A partir de la comunicación pragmática, se analizan los axiomas comunicacionales en que se fundamenta y lo que se conoce como patologías de esos axiomas. Además se revisan las principales características que distinguen la asertividad en la comunicación y las distintas formas de manipulación que la entorpecen. Del enfoque de Virginia Satir, se presentan los diversos aspectos de la comunicación, tanto funcional como disfuncional y los modelos de comunicación propuestos por esta autora. Se revisan aspectos importantes del enfoque de la comunicación educativa, tales como el control de la distancia, la voz y el cuerpo, las palabras y el situacional; así como los elementos que bloquean el proceso de comunicación y las sugerencias acerca de formas correctas de escuchar. Además, se hace referencia a la necesidad de emplear procesos educativos más holísticos y constructivistas y una comunicación-interrelación horizontal y con equidad. Each of the diverse theories, approaches, and models of communication can provide valuable elements for the attainment of effective communication. This article presents a review of those elements with the goal of providing a better understanding and enhancement of one of the most important processes for human beings: the process of communication. This essay presents the author´s position on the topic. The importance given to human relationships and the stages

  9. Efeitos dos choques fiscais sobre o mercado de trabalho brasileiro

    Directory of Open Access Journals (Sweden)

    Diogo Baerlocher Carvalho

    2013-06-01

    Full Text Available Esse trabalho tem por objetivo entender quais os efeitos dos choques fiscais sobre o mercado de trabalho brasileiro. Em particular, utiliza se uma abordagem SVAR para avaliar esses efeitos sobre o emprego e o salário real. Os choques fiscais são identificados a partir da imposição de restrições de sinais puras sobre a relação dinâmica entre os gastos do governo, o produto real e a oferta de trabalho. As restrições são obtidas a partir de funções de resposta a impulso Bayesianas derivadas de um modelo DSGE na tradição da Nova Síntese Neoclássica. As funções de resposta a impulso obtidas a partir da abordagem SVAR mostram que choques fiscais aumentam o salário real e o emprego.

  10. Revisitando uma carta em português sobre Sabbatai Zvi

    Directory of Open Access Journals (Sweden)

    Rodrigues da Silva Tavim, José Alberto

    2007-06-01

    Full Text Available The present paper deals with the Iberian context of the production-translation of a text in Portuguese language about Shabbatai Zevi, in 1666. We refer the production of similar texts and the information about the adherents in Spain, mostly in Malaga. We reflect on the various messsianic currents that crossed the different social groups in Portugal. We present a text that proves the spreading of news about Shabbatai in Portuguese Lands, and the interest kindled among the Portuguese Conversos. And we place the hypothesis that this text to the movement of Shabbatai, could have different readings, among them one that could be convenient to the conversos.

    Este artículo aborda el contexto de la producción-traducción de un texto en portugués sobre Sabetay Sebí, en 1666. Se alude a la producción de otros textos similares y a la información sobre los adeptos del movimiento en España, sobre todo en Málaga. Se reflexiona sobre las varias corrrientes mesiánicas que cruzaban los diferentes grupos sociales en Portugal. Se presenta un texto que prueba la divulgación de noticias sobre Sabetay, en tierras portuguesas y del interés desperttado entre los medios conversos sobre el movimiento. Y se plantea la hipótesis de que este texto contrario al movimiento de Sabbatai pudiera tener varias lecturas, entre ellas una que debería ser conveniente para los conversos.

  11. Santa sexualidad: concepciones de dos monjas sobre feminidad y sexualidad

    OpenAIRE

    Isabel Cristina Giraldo Quijano

    2009-01-01

    En el contexto de la religión católica, la feminidad y la sexualidad femenina se configuran según dogmas y representaciones sociales específicos, en los que la imagen de Cristo -y todo lo que ello implica- actúa como elemento fundamental en la construcción de las concepciones de las mujeres consagradas a la vida religiosa sobre sex ualidad, erotismo, cuerpo. amor. Este artículo pretende explorar desde un punto de vista sociológico las concepciones de dos monjas sobre los temas mencionados....

  12. Datos sobre la vida sexual en dos ciudades colombianas

    OpenAIRE

    Giraldo Neira, Octavio

    2012-01-01

    Uno de los temas más difíciles de investigar científicamente es el referente a la vida sexual, principalmente por la dificultad de obtener datos precisos y verídicos sobre la conducta de los individuos. Este es un tema que se trata vagamente ó solo a través de la consulta médica ó el chiste. Resulta difícil preguntar a la gente sobre su conducta sexual y más difícil aun obtener una respuesta verdadera y clara. Este informe, aunque breve, ha logrado en parte eludir estos escollos. En primer lu...

  13. Fiscalidad de las entidades financieras. Impuesto sobre Sociedades

    OpenAIRE

    Muñoz Ortega, Julián

    2015-01-01

    Las entidades de crédito experimentan cambios de calado en su tributación directa con la reforma 2014 del Impuesto sobre Sociedades, en especial por lo que respecta a la nueva regulación de las pérdidas por deterioro y la doble imposición nacional e internacional Archivo con presentación de las novedades más relevantes a aplicar por entidades de crédito a partir de la Ley 27/2014, de 27 de noviembre, del Impuesto sobre Sociedades

  14. Diálogos sobre juventudes : Estudios de otras miradas

    OpenAIRE

    Fornasari, María Elisa; Decca, Lorena

    2012-01-01

    Medina, Gabriel (ed.) (2009). Juventudes, territorios de identidad y tecnologías. Círculo de Reflexiones de Estudios Poscoloniales. Universidad Autónoma de la Ciudad de México. México. Los estudios sobre juventud/es han seguido diversas trayectorias y han sido abordados desde diferentes perspectivas a partir de su visibilización como problemática. El libro de Gabriel Medina parte de un diagnóstico: la existencia de importantes vacíos en los estudios sobre lo joven y la vigencia de trabajos...

  15. La perspectiva cualitativa en los estudios sobre pobreza

    OpenAIRE

    Mateo Pérez, Miguel A.

    2002-01-01

    Los estudios sobre pobreza internacional han estado marcados por el enfoque cuantitativo. Sin embargo desde hace unos años los estudios cualitativos están adquiriendo una gran relevancia. Este artículo presenta las características de un estudio cualitativo sobre pobreza y género realizado en España durante los últimos tres años, estableciendo algunas líneas de trabajo básicas para el estudio de la pobreza desde la perspectiva cualitativa.

  16. Códigos y grafos sobre anillos de enteros complejos

    OpenAIRE

    Martínez Fernández, María del Carmen

    2007-01-01

    RESUMEN: El objetivo de esta tesis es definir códigos perfectos sobre diferentes espacios de señal multidimensionales. Para resolver este problema, esta memoria presenta una relación original entre las Teorías de Grafos, Números y Códigos. Uno de nuestros principales resultados es la propuesta de una métrica adecuada sobre constelaciones de señal de tipo cuadrático, hexagonal y cuatro-dimensional. Esta métrica es la distancia entre los vértices de una nueva clase de grafos de Cayley definidos...

  17. Banco Interamericano de Desarrollo informe sobre sostenibilidad 2010

    OpenAIRE

    Banco Interamericano de Desarrollo (BID)

    2011-01-01

    Este es el sexto Informe Anual sobre Sostenibilidad del Banco. Cubre el progreso y desempeño del Banco Interamericano de Desarrollo en materia de sostenibilidad durante el año fiscal 2010. El documento proporciona información sobre las tendencias fundamentales del desarrollo y las dimensiones relacionadas con la sostenibilidad en América Latina y el Caribe. Estas tendencias afectan, tanto positiva como negativamente, la capacidad de los países para garantizar la sostenibilidad, el crecimiento...

  18. Concepciones implícitas sobre el desarrollo infantil

    OpenAIRE

    Vilar Martínez, C.; Blasco Cubedo, María Jesús; Hernández Blasi, Carlos

    2001-01-01

    Setenes Jornades de Foment de la Investigació de la FCHS (Any 2001-2002) Partiendo del trabajo de Martí, E. et al. (1994) “ Ideas previas de una población universitaria sobre el desarrollo infantil” hemos realizado un estudio descriptivo para identificar las concepciones implícitas del conocimiento que tienen estudiantes universitarios sobre el desarrollo infantil. La muestra estaba constituida por 111 estudiantes de la Universitat Jaume I, con una media de edad de 19 años. Median...

  19. La tributación estatal sobre los residuos nucleares

    OpenAIRE

    Rozas Valdés, José Andrés

    2014-01-01

    Este trabajo se dedica al análisis pormenorizado de los nuevos impuestos estatales -'Impuesto de la producción de combustible nuclear gastado y residuos radiactivos resultantes de la generación de energía nucleoeléctrica' y el 'Impuesto sobre el almacenamiento del combustible nuclear gestado y residuos radiactivos en instalaciones centralizadas'- a partir de sus fundamentos, para terminar con unas consideraciones sobre su compatibilidad con las tasas equivalentes y con los impuestos autonómic...

  20. UN PENSAMIENTO EMERGENTE SOBRE EL ARTE CONTEMPORÁNEO

    OpenAIRE

    Ingrid Solana

    2009-01-01

    Este artículo trata de configurar un pensamiento emergente en torno a la reflexividad actual sobre el arte. Para ello, se analizan el stencil y el net.art como medios expresivos eminentemente autocríticos. Este ensayo recoge algunos aspectos teóricos sobre el pensamiento actual en torno al arte. Se basa, en su mayor parte, en las teorías estéticas de Gilles Deleuze y de Félix Guattari en ¿Qué es la filosofía?, aunque señala múltiples problemáticas que conciernen al pensamiento posmoderno. Las...

  1. Expression of regulatory CD4+CD25+ Treg,CD4+CD25higTreg cells and Foxp3 mRNA in wheezing infants and its clinical significance%CD4+CD25+、CD4+CD25hig调节性T细胞和Foxp3mRNA在婴幼儿喘息中的表达及意义

    Institute of Scientific and Technical Information of China (English)

    彭力; 钟礼立; 黄寒; 厉娟; 梁沫; 李云

    2012-01-01

    Objective To evaluate the changes of CD4+ CD25+ Treg,CD4 +CD25hig Treg and Foxp3 mRNA in peripheral blood from wheezing infantsMethods Fifty-one wheezing infants and twenty healthy volunteers were included in this study. The proportion of CD4 + CD25 + Treg and CD4 + CD25hig Treg population in total T cells was evaluated by flow cytometric analysis. The expression of Foxp3 mRNA was tested by flow cytometry. Total serum IgE of wheezy infants was detected by enzyme immunoassay. Results Compared with those of healthy control, the frequency of CD4 + CD25 + Treg and CD4 + CD25hig Treg in the peripheral blood from wheezing infants showed a significant increase (6. 31 + 2. 96) % / (3.52 + 1.46) % ,P<0. 01 ,P<0. 01, respectively).The expression of CD4 + CD25+ Treg,CD4 + CD25hig Treg and Foxp3 mRNA in peripheral blood from wheezing infants with atopy burden was lower than those from non-wheezing infants(P<0. 05). The correlation analysis showed that CD4 + CD25hig Treg (r= -0. 75 , P<0.01) and Foxp3 mRNA(r= -0. 61,P<0. 01) had significantly positive relation with total serum IgE,while CD4+CD25 + Treg had significantly negative relation with total serum IgE(r=0. 36,P<0. 05). Conclusion CD4+CD25+ Treg, CD4+CD25hig Treg and Foxp3 mRNA play an important role in activation of wheezing infants.%目的 探讨婴幼儿喘息CD4+CD25+、CD4+CD25hig调节性T细胞(Treg)和叉头/翼状螺旋转录因子(Foxp3)mRNA的表达及意义.方法 采用流式细胞术检测51例首次喘息婴幼儿外周血CD4+CD25+Treg和CD4+CD25higTreg的比例,RT-PCR检测Foxp3 mRNA的表达量,酶联免疫吸附法(ELASA)检测总IgE水平,并与正常婴幼儿对照.结果 喘息婴幼儿外周血CD4+CD25+Treg、CD4+CD25higTreg占CD4+T细胞的百分比分别为(6.31+2.96)%和(3.52+1.46)%,均明显低于健康对照组(P<0.01);特应征喘息组CD4+CD25+Treg、CD4+CD25higTreg及Foxp3 mRNA表达均低于非特应征喘息组(P<0.05).喘息患儿CD4+CD25higTreg百分率及Foxp3 mRNA表达与

  2. Efecto in vitro de aceites esenciales de tres especies de lippia sobre moniliophthora roreri (cif. y par.) evans et al., agente causante de la moniliasis del cacao (theobroma cacao l.)

    OpenAIRE

    Lozada, Betty Stefany; Herrera, Laura Viviana; Perea, Janeth Aidé; Stashenko, Elena; Escobar, Patricia

    2012-01-01

    Se evaluó el efecto antifúngico in vitro de cinco aceites esenciales (AEs) (AE1, AE2, AE3, AE4 y AE5) extraídos de Lippia origanoides, L. citriodora y L. alba sobre aislados de monilia (Moniliophthora roreri) obtenidos de frutos de cacao infectados provenientes de San Vicente de Chucurí, Santander, Colombia. Las plantas de Lippia fueron colectadas en cinco localidades colombianas. Los aislados de monilia (M1, M2, M3, M4 y M5) fueron caracterizados por su morfología, germinación y crecimiento ...

  3. "Meu prazer agora é risco": sentidos sobre sexualidade entre jovens de um grupo sobre saúde

    OpenAIRE

    João Paulo Pereira Barros; Veriana de Fátima Rodrigues Colaço

    2013-01-01

    A sexualidade assumiu a condição de centralidade subjetiva pelo entrecruzamento de diversos demarcadores da Modernidade, como a legitimação do saber-verdade da ciência, a afirmação da individualidade e a institucionalização dos segmentos infanto-juvenis. Partindo dessa premissa, este artigo analisa sentidos produzidos por jovens sobre "sexualidade" em um grupo de discussão sobre saúde, com base em uma pesquisa-intervenção operacionalizada por observações-participantes e pela formação de ofici...

  4. Protocolo de kyoto: debate sobre ambiente y desarrollo en las discusiones sobre cambio climático

    OpenAIRE

    Rodríguez S. Liliana

    2008-01-01

    El comportamiento climático del planeta y sus consecuencias han propiciado debates sobre los modelos de desarrollo de los países responsables del deterioro acelerado del ambiente y de los fenómenos naturales por estos días recurrentes. Sin embargo, países como Estados Unidos, luego de firmar compromisos como la Convención sobre Cambio Climático, rehúsan adquirir las obligaciones del Protocolo de Kyoto, por temor a sufrir deterioro en sus economías. En este escenario, donde la nació...

  5. Controversia sobre el origen del anime. Una nueva perspectiva sobre el primer dibujo animado japonés

    OpenAIRE

    Horno López, Antonio

    2012-01-01

    Recientes descubrimientos sobre los orígenes de la animación japonesa muestran indicios consistentes de que la primera animación nipona en formato cinematográfico data de la década de 1900, lo que puede llegar a cuestionar algunos aspectos fundamentales que sustentan la historia de la animación tradicional. En este artículo se realiza un análisis de la documentación existente sobre las primeras animaciones japonesas, demostrando que este peculiar estilo de animación tuvo en realidad un origen...

  6. Puente metálico sobre el río Save

    Directory of Open Access Journals (Sweden)

    Schafer, G.

    1963-03-01

    Full Text Available The original «Kinfi Alexander» suspension bridge over the Save river, Yugoslavia, which was destroyed during the last world war has been reconstructed, after organising an international prize award for its design. 32 projects from various countries were submitted. The chosen design is a metal structure, of 261 ms span. The arch of the main span has a hollow box section. The deck consists of an orthotropic slab, which has been subjected to a number of tests. The bridge has three spans (two approach and one central span, and was built without scaffolding, i. e., by cantilevering it from the springers. The roadway is 12 ms wide and there are two 3 ms wide footways. The box section arch girders are 9.60 ms deep over the piles, and 4.50 ms at the crown. The slopes on either side of the crown are 0.7 and 0.25%, respectively. The deck is very rigid, and is well capable of supporting the design loads and windage.El primitivo puente colgante Rey Alejandro, sobre el río Save, Yugoslavia, destruido durante la última guerra mundial, ha sido reconstruido por la vía de concurso internacional, al cual se presentaron 32 proposiciones de diferentes países. La solución aceptada fue una estructura metálica de 261 m de luz. El arco de este tramo tiene una sección hueca en forma de cajón. El tablero se compone de una placa ortotrópica, de la que, previamente, se han realizado varios ensayos. La obra, de tres tramos —dos para los accesos y uno central—, se construyó por procedimientos sin andamiaje, es decir, en voladizo. La anchura de la calzada es de 12 m, y dos andenes, de 3 m cada uno, para peatones. Los arcos de las vigas cajón tienen 9,60 m de canto sobre las pilas y 4,50 m en la clave. Las pendientes hacia uno y otro lado de la clave son del 0,7 y 0,25%, respectivamente. La rigidez del tablero es perfecta y suficiente para- soportar las cargas previstas y para transmitir los efectos del viento a las pilas.

  7. Construcciones sociales sobre mujeres desde el discurso jurídico en sentencias penales sobre infanticidio

    Directory of Open Access Journals (Sweden)

    María Eugenia Gastiazoro

    2015-12-01

    Full Text Available El infanticidio como figura penal se suprime del Código Penal Argentino en 1994, para ser una figura de homicidio agravado por el vínculo con prisión o reclusión perpetua. Diez años después de su última derogación, el caso Romina Tejerina en Jujuy generó una serie de cuestionamientos respecto de su penalización. Otro caso, que tomó estado público fue el de Eli Díaz en la ciudad de Villa Dolores en Córdoba, juzgada en el 2006, siendo (en contraposición al caso Tejerina absuelta por una mayoría compuesta solo de ciudadanos comunes (jurados. En el presente trabajo se analiza la construcción y la producción que desde el discurso jurídico se hace de las diferentes mujeres en los casos de infanticidio. A su vez, estas imágenes se comparan con las representaciones que los legisladores tuvieron en el debate del Congreso del año 2010 cuando se intentó reponer la figura. La sujeción del género centrada en la buena o mala madre, mujer, esposa, en intersección con otras dimensiones de clase social, y edad, se categoriza en el discurso de los tribunales de acuerdo a imaginarios sociales que sostienen una identidad normativa sobre estas mujeres.

  8. Sobre-educación en el mercado laboral colombiano

    Directory of Open Access Journals (Sweden)

    Jhon James Mora

    2008-12-01

    Full Text Available Este artículo analiza la sobre-educación en Colombia con datos de individuos y empresas compilados por el Servicio Nacional de Aprendizaje de Colombia en 2006, encuentra que la probabilidad de estar sobre-educado es del 14% y que depende de la movilidad entre áreas de desempeño, la experiencia, el género, el tamaño de la empresa y el nivel de educación. Los trabajadores sobre-educados ganan un 2% menos que los trabajadores correctamente educados, conforme al patrón internacional. Los resultados también muestran que la probabilidad de que los profesionales permanezcan en la misma área de desempeño aumenta con la experiencia, que cuanto mayor es la sobre-educación menor es la probabilidad de permanecer en dicha área y que los trabajadores con postgrado tienen menor probabilidad de permanecer en su área de desempeño.

  9. Reflexiones sobre la dirección de centros

    OpenAIRE

    Felpeto, Ángel

    2004-01-01

    Se presenta una reflexión sobre el modelo de dirección de centros desde la experiencia en la gestión de dos centros educativos de muy diferente tamaño y en diferentes épocas. El autor plantea la necesidad de un director líder, que encabece un proyecto educativo gestionado por un equipo.

  10. Sobre el costo de los protocolos de commitment

    OpenAIRE

    Zanconi, Marcelo; Ardenghi, Jorge Raúl

    1995-01-01

    Se presenta en este trabajo, una evaluación sobre los costos de los protocolos de terminación en dos fases, relacionados con la correctitud y la serializabilidad, considerando los mecanismos de apropiación de recursos basados en locking, time-sta.mping y control optimista.

  11. SONETO SOBRE O MISTÉRIO DO AMOR

    Directory of Open Access Journals (Sweden)

    Jorge Antunes

    2012-01-01

    Full Text Available SONETO SOBRE O MISTÉRIO DO AMOR Dedicado ao Prof. Dioney Moreira Gomes Jorge Antunes Um expert em linguística pariu dois meninos simpáticos, felizes. De um homem que era só então surgiu planta viçosa plena de raízes.

  12. Reflexiones y recomendaciones sobre la poda de frutales

    OpenAIRE

    Urbina Vallejo, Valero; Dalmases Mestre, Josep; Pascual Roca, Miquel

    1999-01-01

    Ante la nueva campaña de poda invernal se plantean una serie de consideraciones que pueden ser de utilidad para el fruticultor a la hora de tomar decisiones en la planificación de la poda y en la ejecución de las diferentes intervenciones que se llevan a cabo sobre el árbol.

  13. Aspectos sobresalientes del Informe sobre Sostenibilidad de 2012

    OpenAIRE

    Banco Interamericano de Desarrollo (BID)

    2013-01-01

    Este Informe sobre Sostenibilidad abarca el progreso y desempeño del Banco Interamericano de Desarrollo en materia de sostenibilidad durante el ejercicio fiscal de 2012. En este informe nos enfocamos en el tema emergente de la gestión de recursos hídricos.

  14. Apuntes de José Antonio Valverde sobre dientes

    OpenAIRE

    Valverde Gómez, José Antonio, 1926-2003

    2008-01-01

    Apuntes sobre dientes, que el autor utilizó para elaborar su conferencia "L'Evolution Humaine Apercue Generale", impartida en el Musèe de l'Homme de París, y patrocinada por la Société d’Anthropologie de Paris, el 21 de marzo de 1963.

  15. Apuntes de José Antonio Valverde sobre manos

    OpenAIRE

    Valverde Gómez, José Antonio, 1926-2003

    2008-01-01

    Apuntes sobre manos, que el autor utilizó para elaborar su conferencia "L'Evolution Humaine Apercue Generale", impartida en el Musèe de l'Homme de París, y patrocinada por la Société d’Anthropologie de Paris, el 21 de marzo de 1963.

  16. Las competencias sobre cooperativas y econom??a social

    OpenAIRE

    P??rez-Villalobos, M. Concepci??n

    2007-01-01

    El cap??tulo desarrolla la competencia sobre cooperativas y econom??a social de las Comunidades Aut??nomas espa??olas. El t??rmino "econom??a social" es nuevo en los Estatutos de autonom??a, aunque la constituci??n espa??ola apost?? fuerte por ??l como instituci??n que coopera al desarrollo del Estado social

  17. Sobre o estilo e o modo de falar e escrever

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    Pedro Caruso

    2001-02-01

    Full Text Available

    Este trabalho apresenta o texto crítico de uma Lei ou Provisão de Filipe I , rei de Portugal, sobre as diversas formas de tratamento no período arcaico da língua portuguesa.

  18. Integración de las actuales definiciones sobre función ejecutiva

    OpenAIRE

    Cadavid Ruiz, Natalia; Río Pereda, Pablo del; Martínez, R.

    2007-01-01

    Cartel expositivo del curso sobre Integración de las actuales definiciones sobre función ejecutiva realizado por la Universidad de Salamanca en colaboración con la Universidad Carlos III de Madrid.

  19. Influences of androgen on the growth of human prostate cancer PC-3M model in nude mice and the changes of the androgen receptor levels and protein kinase C activity

    International Nuclear Information System (INIS)

    Nude mice bearing transplanted human prostate cancer cell line PC-3M were treated with male sex hormone. Results demonstrated that low dose of testosterone propionate (TP) (50 mg/kg wt.) stimulated the tumor growth, and the androgen receptor (AR) levels and protein kinase C (PKC) activity were elevated in the tumor tissue. On the contrary higher dose of TP (400 mg/kg wt.) inhibited the tumor growth, and the AR level and PKC activity in tumor tissue were reduced significantly. These results showed that TP has a biphasic effect on the growth of human prostate cancer PC-3M cell line. The mechanism of the biphasic effect and its relationship between AR and PKC levels are also discussed

  20. "Meu prazer agora é risco": sentidos sobre sexualidade entre jovens de um grupo sobre saúde

    Directory of Open Access Journals (Sweden)

    João Paulo Pereira Barros

    2013-04-01

    Full Text Available A sexualidade assumiu a condição de centralidade subjetiva pelo entrecruzamento de diversos demarcadores da Modernidade, como a legitimação do saber-verdade da ciência, a afirmação da individualidade e a institucionalização dos segmentos infanto-juvenis. Partindo dessa premissa, este artigo analisa sentidos produzidos por jovens sobre "sexualidade" em um grupo de discussão sobre saúde, com base em uma pesquisa-intervenção operacionalizada por observações-participantes e pela formação de oficinas sobre saúde, em uma escola pública de Fortaleza. Acerca dos sentidos sobre "sexualidade", as articulações entre "sexualidade" e "risco" se sobressaíram em relação às conexões entre "sexualidade" e "prazer". Isso sugere a força de um viés educativo baseado na scientia sexualis, aludido por Michael Foucault, operando com uma visão normativa-prescritiva da sexualidade, reiterando-a, mediante o signo da "prevenção", como tecnologia de governo. Usando como ferramenta o conceito de biopolítica, aponta-se que tais questões remetem à instalação de um paradigma de "gestão do risco" na contemporaneidade.

  1. Corrosion behaviour of groundnut shell ash and silicon carbide hybrid reinforced Al-Mg-Si alloy matrix composites in 3.5% NaCl and 0.3M H2SO4 solutions

    Directory of Open Access Journals (Sweden)

    Kenneth Kanayo ALANEME

    2015-05-01

    Full Text Available The corrosion behaviour of Al-Mg-Si alloy based composites reinforced with groundnut shell ash (GSA and silicon carbide (SiC was investigated. The aim is to assess the corrosion properties of Al-Mg-Si alloy based hybrid reinforced composites developed using different mix ratios of GSA (a cheaply processed agro waste derivative which served as partial replacement for SiC and SiC as reinforcing materials. GSA and SiC mixed in weight ratios 0:1, 1:3, 1:1, 3:1, and 1:0 were utilized to prepare 6 and 10 wt% of the reinforcing phase with Al‐Mg‐Si alloy as matrix using two‐step stir casting method. Mass loss and corrosion rate measurement was used to study the corrosion behaviour of the produced composites in 3.5% NaCl and 0.3M H2SO4 solutions. The results show that the Al-Mg-Si alloy based composites containing 6 and 10 wt% GSA and SiC in varied weight ratios were resistant to corrosion in 3.5% NaCl solution. The composites were however more susceptible to corrosion in 0.3M H2SO4 solution (in comparison with the 3.5% NaCl solution. It was noted that the Al-Mg-Si/6 wt% GSA-SiC hybrid composite grades containing GSA and SiC in weight ratio 1:3 and 3:1 respectively exhibited superior corrosion resistance in the 0.3M H2SO4 solution compared to other composites produced for this series. In the case of the Al-Mg-Si/10 wt% GSA-SiC hybrid composite grades, the corrosion resistance was relatively superior for the composites containing a greater weight ratio of GSA (75% and 100% in 0.3M H2SO4 solution.

  2. Comparison of 3M Petrifilm Aerobic Count Plates to standard plating methodology for use with AOAC antimicrobial efficacy methods 955.14, 955.15, 964.02, and 966.04 as an alternative enumeration procedure: collaborative study.

    Science.gov (United States)

    Nelson, Maria T; LaBudde, Robert A; Tomasino, Stephen F; Pines, Rebecca M

    2013-01-01

    A multilaboratory study was conducted to determine the equivalence of the 3M Petrifilm Aerobic Count Plate and standard plating methodology for measuring viable bacteria and spores recovered from hard-surface carriers (stainless steel and porcelain), also known as "control carrier counts," used in AOAC antimicrobial efficacy test methods. Six laboratories participated in the study in which carriers inoculated with Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella enterica, and spores of Bacillus subtilis were evaluated using 3M Petrifilm Aerobic Count (AC) plates and standard plating side-by-side. The data were analyzed using a matched-pair t-test to determine the between-method effect with confidence intervals. For all test organisms pooled across all laboratories, the mean difference in log10 concentration between the standard plate count method and 3M Petrifilm AC Plates was -0.012, with a 95% confidence interval of (-0.090, +0.066), which was well within the -0.5, +0.5 interval established as the acceptance criterion. The between-carrier SD averaged 0.139; the between-replicate SD was 0.050. The carrier reproducibility, given that a single replicate per carrier is done, was estimated to be 0.148. Although differences were seen in the final concentrations of the test organisms among laboratories, there were no statistical differences between the enumeration methods. Based on the results from this study, 3M Petrifilm AC Plates are equivalent to standard plating methodology and can be used as an alternative procedure for the enumeration of test organisms used in AOAC Methods 955.14, 955.15, 964.02, and 966.04.

  3. Rapamycin inhibited the proliferation of prostate carcinoma cell line PC-3M-2B4 in vitro%雷帕霉素抑制人前列腺癌细胞增殖及其作用机制

    Institute of Scientific and Technical Information of China (English)

    郑航; 胡伟; 郑新民; 李世文; 王行环

    2011-01-01

    目的 观察雷帕霉素(Rapamycin)对体外培养的人前列腺癌PC-3M-2B4细胞增殖及凋亡的影响,探讨其机制.方法 分别用不同浓度的雷帕霉素(100、200、400、800μg/L)对细胞进行干预后,采用噻唑蓝(MTT)比色法检测细胞增殖变化,流式细胞术检测细胞凋亡变化,Western blot 法检测凋亡相关蛋白bcl-2及bax表达的变化.结果 雷帕霉素能明显抑制PC-3M-2B4细胞的增殖活性,此作用呈现量-效、时-效关系.雷帕霉素呈浓度依赖性诱导细胞凋亡.雷帕霉素作用PC-3M-2B4细胞后,细胞内凋亡抑制蛋白bcl-2的表达明显降低,bax蛋白的表达明显增加.结论 雷帕霉素能够通过调节凋亡相关蛋白bcl-2和bax的表达比例,诱导前列腺癌细胞凋亡,从而抑制肿瘤生长.%Objective To investigate the effects of Rapamycin on the growth and apoptosis of human prostate carcinoma cell line PC-3M-2B4. Methods The inhibitory effect of Rapamycin was observed at 100,200,400,800μg/L on the growth of human prostate carcinoma cell line PC-3M-2B4 in serum-free medium for different concentrations by methyl thiazol tetrazolium (MTF) assays. Flow cytometry (FCM)analysis was used to study the changes of cell apoptosis. The expression level of bcl-2 and bax was determined by Western blotting. Results Rapamycin caused dose-dependent inhibition on the growth of human prostate carcinoma cell line PC-3M-2B4 in a concentration-and time dependent manner. Rapamycin induced the apoptosis of PC-3M-2B4 cells in a concentration-dependent manner. The levels of bcl-2 protein were reduced gradually with the increase of concentration or action time. Conclusion Rapamycin, a mTOR inhibitor, inhibits the growth of human prostate cancer cell and induces apoptosis of human prostate cancer cell. mTOR might be a potential target for anti-prostate cancer.

  4. EL PENSAMIENTO SOCIAL SOBRE EL SUICIDIO EN ESTUDIANTES DE BACHILLERATO

    Directory of Open Access Journals (Sweden)

    Gabriel Montes Sosa

    2009-01-01

    Full Text Available En este estudio se analiza desde el marco de las representaciones sociales cómo los jóvenes preparatorianos manifiestan su pensamiento social sobre el suicidio. Se aplicaron cuestionarios abiertos a 169 jóvenes, mujeres y varones de bachillerato, para conocer la ocurrencia potencial de suicidio, las situaciones a las que se debe y su definición. Los resultados muestran que los jóvenes organizan su idea sobre el suicidio a partir de varios elementos en común: problemas diversos, depresión, baja autoestima y comunicación deficiente. Así, el suicidio se objetiviza en estos esquemas y se ancla en sus relaciones existentes. Para contextualizar el estudio, en la primera parte del trabajo los autores incluyen una somera descripción de los datos estadísticos más importantes respecto del suicidio en el estado de Puebla.

  5. Preguntas y consideraciones sobre anestesia en el anciano

    OpenAIRE

    Evangelina Dávila Cabo de Villa

    2011-01-01

    El avance en los conocimientos sobre la fisiopatología de las enfermedades, apoyado por los adelantos científicos ha hecho posible la realización de mayor número de procedimientos quirúrgicos y con más complejidad, bajo la aplicación de métodos anestésicos y con calidad en los desempeños. El empleo juicioso de fármacos, la actualización tecnológica, la preocupación por crear mayores beneficios en los enfermos, conforman objetivos fundamentales en la anestesiología, sobre todo en ancianos. Es...

  6. Consenso Cultural sobre el Intento de Suicidio en Adolescentes

    Directory of Open Access Journals (Sweden)

    Javier Eduardo García de Alba García

    2011-01-01

    Full Text Available Este estudio buscó identificar la estructura semántica del dominio cultural, el promedio de conocimiento y el grado de consenso cultural manifestado por los adolescentes sobre el intento de suicidio. Fue un estudio cualitativo de listas libres, con un muestreo propositivo no aleatorizado de 27 adolescentes entre 13 y 18 años. Los resultados evidenciaron un solo modelo semántico. En lo estructural se identificó el problema familiar como una causa importante del intento suicida; las categorías depresión y tristeza se consideraron como signos y síntomas previos a esta tentativa y no como causas. Como estrategias de prevención, se consideró recibir información mediante pláticas o establecer conversaciones sobre los problemas. Este modelo permite proponer estrategias de prevención que privilegien el núcleo familiar.

  7. Passagens sobre o moderno na cidade de Georg Simmel

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    Felipe Ziotti Narita

    2013-07-01

    Full Text Available Este trabalho sugere alguns pontos para reflexão sobre o ensaio “As grandes cidades e a vida do espírito” (publicado em 1903, de Georg Simmel. Trata-se, fundamentalmente, de discutir as principais balizas teóricas e conceituais construídas pelo autor para refletir sobre a vida urbana, analisando, a partir das formas das interações sociais, as próprias especificidades da modernidade. Além do citado ensaio, este artigo discute as análises de Simmel à luz de alguns debates sociológicos de seu tempo, tomando como referência o conjunto mais amplo de seus trabalhos e interlocutores.

  8. Sobre a Pesquisa nas Artes: um discurso amoroso

    Directory of Open Access Journals (Sweden)

    Victoria Pérez Royo

    2015-09-01

    Full Text Available Este artigo resulta de um exercício de reescrita experimental e de um pensamento analógico cujo objetivo era abrir uma nova perspectiva sobre pesquisa nas artes. Metodologicamente, as diferentes figuras de amor no livro Fragmentos de um Discurso Amoroso, de Barthes, são levadas a conversar sobre a relação entre pesquisador e objeto de estudo. Essa analogia nos permite encontrar parâmetros de qualidade baseados em uma escala de valores diferentes dos hegemônicos na academia (produtividade, competitividade, inovação. Esses novos parâmetros podem constituir uma sólida base ontológica para a construção de uma nova política de pesquisa artística na academia que permita uma reconsideração radical dos processos de investigação em artes.

  9. Dialogos negativos anotaciones sobre el montaje de Medea Okupa

    Directory of Open Access Journals (Sweden)

    Marcelo José Islas

    2013-09-01

    Full Text Available En este texto hablamos de dos temas: la adaptación de una obra de Eurípides, ]Medea, y su montaje en el contexto de un espacio público a partir de un trabajo de investigación en actuación sobre la poética de la tragedia.Estos dos temas, que exponemos por separado una mejor comprensión.

  10. Sobre inundaciones y anegamientos / Reflections on floods and flooding

    Directory of Open Access Journals (Sweden)

    Ferrando A., Francisco J.

    2006-11-01

    Full Text Available Respecto a anegamientos e inundaciones, el autor realiza algunas precisiones conceptuales que afectan la gestión de acciones preventivas, la planificación y el ordenamiento territorial; además se ofrece una sistematización del quehacer sobre las inundaciones./ The author punctualizes the concepts regarding preventive actions and territorial planning. Also the article includes a systematized list of actions related to flood management.

  11. El buen vivir repolitiza los debates sobre el desarrollo

    OpenAIRE

    Gudynas, Eduardo

    2014-01-01

    El presente texto relaciona una importante entrevista realizado por Eduardo Gydynas, Investigador en el Centro Latino Americano de Ecología Social (CLAES), de Montevideo, Uruguay, al pensador Arturo Escobar. Se trató de un abierto diálogo donde el entrevistado, comenta algunas vertientes sobre las alternativas al desarrollo y el Buen Vivir. Encuentro personal, realizado en la Universidad de North Carolina, en mayo de 2015.

  12. La red sobre trabajo infantil peligroso (Red Tip

    Directory of Open Access Journals (Sweden)

    Walter Varillas

    2003-01-01

    Full Text Available En el mundo, aproximadamente 351.7 millones de niños entre 5 y 17 años realizaban algún tipo de actividad económica, de ellos 170.5 millones (48.5% realizaban algún tipo de trabajo considerado peligroso. Un alto porcentaje se encuentra en la agricultura, otros en minas, manufacturas, ladrilleras, predominantemente en la economía informal. El Convenio 138 (cobre la edad mínima de admisión en el empleo de la OIT y el Convenio 182 (sobre las peores formas de trabajo infantil, definen como trabajo infantil peligroso el que puede afectar la salud, seguridad y moralidad de los menores. Estudios específicos sobre los menores muestran su susceptibilidad particular frente a los riesgos laborales, aumentando la peligrosidad para su normal desarrollo y crecimiento: "los niños no son adultos pequeños". Los profesionales de la seguridad y salud en el trabajo pueden colaborar con los profesionales y las organizaciones especializadas en el trabajo infantil, en la definición y caracterización de lo que significa el trabajo infantil peligroso. Para ello se ha conformado la Red sobre Trabajo Infantil Peligroso (Red TIP, con la finalidad de articular estos dos espacios, orientados a eliminar el trabajo infantil peligroso y rescatar al menor y devolverle la oportunidad de sonreír ahora y en el futuro.

  13. Variações sobre a porta barroca

    Directory of Open Access Journals (Sweden)

    Roger Bastide

    2006-07-01

    Full Text Available Publicado em francês no segundo número da revista Habitat (São Paulo, 1951, com fotografias de Pierre Verger, "Variações sobre a porta barroca" é um ensaio que sintetiza linhas de força da obra de Roger Bastide. Com foco em igrejas da Bahia e de Pernambuco, o autor tece formulações iluminadoras sobre a função sociológica da porta e, por extensão, da ornamentação no barroco brasileiro.First published in French in the second issue of Habitat (São Paulo, 1951, with photographs by Pierre Verger, "Variações sobre a porta barroca" is an essay that is representative of Roger Bastide’s work in Brazil. Taking churches in Bahia and Pernambuco as an example, the author formulates challenging interpretations about the sociologial function of the door and ornaments during Baroque period in Brazil.

  14. AUTOPERCEPCIÓN DE LOS ADULTOS MAYORES SOBRE SU VEJEZ*

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    Sagrario Garay Villegas

    2010-03-01

    Full Text Available El objetivo de este artículo es aproximarse a los significados y percepciones que tienen los adultos mayores sobre esta etapa de su vida. Para ello utilizaremos herramientas de carácter cualitativo y cuantitativo. Nuestra pretensión de usar ambos métodos es contar con la visión de la población con 60 años o más, sobre aspectos relacionados con su salud física y mental, pero también indagar el los factores que podrían estar influyendo en dicha percepción. Los resultados encontrados nos revelan que existe una asociación muy cercana entre la percepción sobre la salud física y el estado mental de las personas adultas mayores. Palabras clave: vejez; significados; salud mental; salud física y felicidad. * Agradecemos los valiosos comentarios a versiones preeliminares de este documento realizados por la Dra. Verónica Montes de Oca.

  15. Conhecimentos de estudantes de enfermagem sobre distanásia

    Directory of Open Access Journals (Sweden)

    Mariana Costa Matos

    2015-01-01

    Full Text Available Objetivo: evaluar conocimientos de estudiantes de enfermería sobre distanasia como proceso de intervención humana en pacientes terminales. Métodos: estudio cualitativo, con 28 estudiantes de enfermería de una institución de educación superior pública. Análisis de datos de las entrevistas se realizó a través del análisis de contenido temático. Resultados: la mayoría de los estudiantes no entienden el significado de la distanasia, aunque conviven con situaciones de esta práctica en sus campos de entrenamiento. Los que definieron el término, describieron como prolongación excesiva de la vida o muerte sufrida con mucho dolor, tratamiento agresivo que sólo prolonga el proceso de morir. Conclusión: los estudiantes de enfermería presentaron conocimientos insuficientes sobre la distanasia y es necesario ampliar los espacios de discusión en posgrado y realización de estudios sobre el tema, relacionándolo con la muerte y el morir, con finalidad de preparación de los futuros profesionales de la salud.

  16. Sobre os conceitos de risco em Luhmann e Giddens

    Directory of Open Access Journals (Sweden)

    Marília Luz David

    2011-11-01

    Full Text Available http://dx.doi.org/10.5007/1806-5023.2011v8n1p30 O presente artigo discute as contribuições de Anthony Giddens e Niklas Luhmann para uma melhor definição do conceito de risco, tendo em vista o rigor teórico de ambos os autores. Inicialmente é feita uma breve exposição sobre como o conceito de risco passou a ser utilizado na Modernidade e recebeu a atenção de autores das Ciências Sociais, principalmente a partir da abordagem cultura proposta por Mary Douglas. Em seguida, as definições e correspondentes argumentos sobre o conceito de risco em Luhmann e Giddens são apresentados respectivamente. Finalmente, alguns pontos de distanciamento entre os autores são discutidos e de que maneira cada um contribuiu para o debate sobre os riscos na teoria social e para o diagnóstico da Modernidade.

  17. O Impacto do Mobbing sobre o estresse no trabalho

    Directory of Open Access Journals (Sweden)

    Tássia Donadello Ferreira Lima

    2015-07-01

    Full Text Available Definido como um conjunto de ações hostis e antiéticas, desenvolvidas no ambiente de trabalho de forma sistemática e recorrente que deixa o trabalhador em uma posição indefesa, o mobbing tem sido investigado na sua relação com a saúde e qualidade de vida do trabalhador. Neste sentido, o objetivo no presente trabalho foi (1 o desenvolvimento de três instrumentos para mensuração do mobbing, considerando sua prática por chefes, colegas e subordinados e (2 investigar o impacto do mobbing sobre o estresse no trabalho. Participaram do estudo 300 servidores de uma universidade federal do estado do Rio de Janeiro, sendo 157 homens e 143 mulheres. Os participantes preencheram os três instrumentos para mensuração do mobbing e a EET (Escala de Estresse no Trabalho. A análise fatorial exploratória dos principais eixos com rotação promax revelou uma estrutura ideal de dois fatores em cada instrumento, sendo nomeados de (1 comportamento respeitoso e (2 mobbing praticado por chefes, colegas ou subordinados, conforme o caso. A Modelagem por Equações Estruturais revelou um impacto positivo significativo do mobbing sobre o estresse no trabalho. Da mesma maneira, o comportamento respeitoso por parte de chefes, colegas e subordinados teve influência negativa significativa sobre o estresse no trabalho.

  18. Hegel sobre Tácito y la libertad teutona

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    Valerio Rocco Lozano

    2015-09-01

    Full Text Available Una investigación sobre la presencia (así como sobre la ausencia de Tácito en Hegel es crucial para entender la posición política y filosófica de este pensador, especialmente en la época de Jena. Tras algunas consideraciones sobre el conocimiento hegeliano de la historia y la cultura romanas, se abordará un análisis de su noción de "libertad teutona": Hegel se opone tanto a la neo-romanidad de los revolucionarios franceses como al esencialismo teutómano de los conservadores alemanes (derivado fundamentalmente de un uso fuertemente ideológico de la "Germania" de Tácito, así como a las caducas instituciones imperiales. Esta doble oposición sitúa a Hegel en medio de dos corrientes políticas (e incluso de dos ejércitos en guerra y se lleva a cabo desde una actitud que puede denominarse como “mediación sin nostalgia”

  19. Efectos del D-003 sobre patrones conductuales de roedores

    Directory of Open Access Journals (Sweden)

    Lilia Fernández Dorta

    2005-01-01

    Full Text Available El D-003 es una mezcla de ácidos alifáticos de muy alto peso molecular purificada de la cera de la caña de azúcar con efectos hipocolesterolemizante y antiagregante plaquetario demostrados experimentalmente y en estudios clínicos Fase I y II. Los estudios experimentales y clínicos culminados han mostrado que el D-003 es seguro y bien tolerado. Sin embargo, la farmacología de la seguridad de nuevos medicamentos investiga sus efectos sobre diversos sistemas que pudieran ser blancos potenciales de toxicidad. Teniendo en cuenta que los efectos adversos relacionados con el Sistema Nervioso (SN están entre los más frecuentes para diversas áreas terapéuticas, estos estudios suelen investigar los efectos de las sustancias sobre la función y estructura del SN. La investigación de los efectos sobre patrones conductuales de roedores comúnmente representa la primera etapa de estos estudios. De acuerdo con ello, el presente estudio tuvo como objetivo investigar los efectos del tratamiento oral con D-003 (dosis únicas y repetidas sobre la actividad exploratoria, la respuesta al plato caliente, la sujeción y ejecución en varilla rotatoria y la evitación pasiva de una sola prueba de aprendizaje en ratones. Los animales se distribuyeron aleatoriamente en cinco grupos experimentales (10 animales/grupo: uno control que recibió el vehículo goma acacia-H20 y cuatro tratados con D-003 (5, 25, 100 y 400 mg/kg, respectivamente. El tratamiento oral con dosis únicas y repetidas de D-003 (400 mg/kg aumentó de forma modesta, pero significativa, la actividad exploratoria con respecto al grupo control. Sin embargo, el D-003 no modificó la respuesta en el ensayo de plato caliente, la capacidad de sujeción y ejecución motora en varilla rotatoria ni la retención del aprendizaje en el ensayo de evitación pasiva. Se necesitan estudios ulteriores que diluciden las causas por las cuales el D-003 aumenta la actividad exploratoria en ratones y que

  20. Efecto del D-004 sobre patrones conductuales en roedores

    Directory of Open Access Journals (Sweden)

    Daisy Carbajal Quintana

    2007-01-01

    Full Text Available El D-004 es un extracto lipídico de los frutos de la palma real cubana (Roystonea regia que ha mostrado efectos protectores sobre la hyperplasia prostática (HP inducida en roedores con testosterona, pero no con dihidrotestosterona y que además, antagoniza respuestas mediadas por los ¿1-adrenoreceptores prostáticos. El D-004 mostró una modesta acción antiinflamatoria en el modelo de granuloma por algodón, modelo que se acerca más a la condición de inflamación crónica aparejada a la hiperplasia prostatica benigna (HPB en el hombre, lo que podría contribuir, en alguna medida, a su efecto en los modelos de HP. Teniendo en cuenta que los efectos adversos relacionados con el sistema nervioso (SN están entre los más frecuentes para diversas áreas terapéuticas, es obligado investigar los efectos de las sustancias sobre la función y estructura del SN. La investigación de los efectos sobre patrones conductuales de roedores comúnmente representa la primera etapa de estos estudios. El presente estudio investigó los efectos del tratamiento oral con D-004 (dosis únicas y repetidas sobre la actividad exploratoria, la respuesta al plato caliente y a las contracciones inducidas con ácido acético (200, 400 y 800 mg/kg, así como sobre la sujeción en varilla rotatoria y la fuerza de agarre en ratones (250, 500 y 1 000 mg/kg. El tratamiento oral con D-004 no modificó la actividad exploratoria, la respuesta al plato caliente y a las contracciones inducidas con ácido acético, así como la sujeción en varilla y la fuerza de agarre . El tratamiento oral con D-004 en el intervalo de dosis indicado no indujo efectos neurotóxicos, ya que no modificó ninguna de las conductas estudiadas.

  1. Functionalization of N2 to NH3 via direct N ≡ N bond cleavage using M(III)(NMe2)3 (M=W/Mo): A theoretical study

    Indian Academy of Sciences (India)

    Sambath Baskaran; Perumal Balu; Chinnappan Sivasankar

    2015-01-01

    Atmospheric N2 can be cleaved directly to yield metal-nitride (before proceeding to the functionalization of N of coordinated N2) and subsequently functionalized to ammonia using M(III)(NMe2)3 (M = W/Mo) as a catalyst, and suitable proton and electron sources. The calculated energies of thermodynamic and kinetic states of the various intermediates and transition states in the reaction coordinate to yield ammonia confirmed the viability of the proposed reaction pathway. Rationale of different pathways have been examined and discussed in detail. Changes in the structural features of the catalyst and some important intermediates and transition states have also been examined.

  2. Investigation of the R{sub 2}Te{sub 3}-M{sub 2}Te-PbTe (R = Tb, Dy; M = Cu, Ag) systems at 770 K

    Energy Technology Data Exchange (ETDEWEB)

    Marchuk, O.V. [Department of Physical and Colloidal Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine); Daszkiewicz, M. [W. Trzebiatowski Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna str. 2, P.O. Box 1410, 50-950 Wroclaw (Poland); Gulay, L.D. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine)], E-mail: gulay@lab.univer.lutsk.ua; Olekseyuk, I.D. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine); Pietraszko, A. [W. Trzebiatowski Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna str. 2, P.O. Box 1410, 50-950 Wroclaw (Poland)

    2008-05-08

    The interactions between the components in the R{sub 2}Te{sub 3}-M{sub 2}Te-PbTe (R Tb, Dy; M = Cu, Ag) systems at 770 K were determined using X-ray powder diffraction. The formation of the compounds R{sub 7}Cu{sub 3}Te{sub 12} (Ho{sub 7}Cu{sub 3}Te{sub 12} structure type, space group R3-barm), RCu{sub 5}Te{sub 4} (unknown structure), RAgTe{sub 2} (ErAgTe{sub 2} structure type, space group P4-bar2{sub 1}m) and the solid solutions R{sub (2+x)/3}Cu{sub 2-x}Te{sub 2} (0 {<=} x {<=} 1) (Er{sub 2/3}Cu{sub 2}S{sub 2} structure type, space group P3-bar) in the R{sub 2}Te{sub 3}-M{sub 2}Te sections was observed. No compounds exist in the R{sub 2}Te{sub 3}-PbTe and M{sub 2}Te-PbTe sections. The formation of quaternary compounds was not observed in the investigated systems.

  3. Synthesis and characterization of aluminum and gallium complexes of heterocyclic thiosemicarbazones. crystal structures of Me2M[SC4H3CHNNC(S)SCH3] (M=Al, Ga)

    International Nuclear Information System (INIS)

    The synthesis and characterization of the monomeric group 13 heterocyclic thiosemicarbazone complexes Me2M[SC4H3CHNNC(S)SCH3] (M=Al (2), Ga (3)) are described. Compounds 2-3 were prepared using MMe3 (M=Al, Ga) in toluene with 2-thiophenecarboxaldehyde-S-methyldithiocarbazate under anaerobic conditions. These complexes have been characterized by 1H NMR, 13C NMR, elemental analyses, and single-crystal X-ray diffraction. 2 crystallizes in the monoclinic space group P21/c with unit cell parameters a=10.2930(5) A, b=18.564 (1) A, c=7.3812(6) A, V=1347.9(2) A3, Dcalc=1.342 gcm-3 for Z=4, 9281 reflections with Ibca with unit cell parameters a=13.340(3) A, b=19.9070(5) A, c=11.3690(2) A, V=2673.88(9) A3, Dcalc=1.511 gcm-3 for Z=8, 17004 reflections with I>3σ(I), R1=0.0480 and wR2=0.0524. Compound 3 is a monomeric gallium compound with a weak interaction between the pendant thiophene and the gallium center

  4. 自酸蚀黏结剂加树脂直接充填深龋的临床观察%Clinical effect of Xeno III as 3 m Filtek P60 on treatment of deep caries

    Institute of Scientific and Technical Information of China (English)

    佟小辉; 季丽玢

    2013-01-01

    目的 评价用自酸蚀黏结剂XenoIII(XO)和树脂直接充填深龋窝洞和用全酸蚀黏结剂:Single bond 2加玻璃离子垫底树脂充填深龋窝洞的敏感性比较.方法 选取166个患深龋的磨牙,随机分为实验组和对照组,实验组使用自酸蚀黏结剂XenoIII处理窝洞后直接用树脂3 m Filtek P60充填,对照组采用玻璃离子水门汀(GIC)垫底,后用全酸蚀黏接剂Sing bond 2处理窝洞,树脂3 m Filtek P60充填.分别与充填后7 d,6个月和1年观察.结果实验组和对照组在术后7 d,6个月和1年的敏感性无显著性差异.结论 自酸蚀黏结剂能有效降低树脂充填深龋后的敏感性,提高牙髓的存活率,且操作简单.

  5. Estado del arte del conocimiento sobre perifiton en Colombia

    Directory of Open Access Journals (Sweden)

    Yimmy Montoya Moreno

    2013-12-01

    Full Text Available El perifiton es un componente de las comunidades bióticas acuáticas, su estudio es importante tanto desde la perspectiva ecológica, para comprender el funcionamiento de los ecosistemas acuáticos, como desde el punto de vista ambiental, pues su composición y estructura pueden servir como indicadores de la calidad del agua y de procesos que como la contaminación puedan estar afectando a los ecosistemas. La investigación sobre el perifiton es compleja; la definición misma de perifiton aún genera controversias. Sumado a esto, la variedad de metodologías para su estudio integral, la diversidad de arquitecturas de la matriz perifítica, la gran diversidad de ecosistemas y la ausencia de escuelas taxonómicas en el país, contribuyen a que sean pocos los trabajos que se publican sobre el tema, lo que incrementa el valor e importancia de los estudios reseñados en esta revisión. El objetivo de este artículo es dar a conocer el estado del arte en la investigación sobre el perifiton en Colombia, mediante el análisis de diferentes líneas de investigación que se han desarrollado y su grado de avance. Con este fin, se examinaron 84 trabajos a los que los autores tuvieron acceso. La mayoría de investigaciones consultadas en este trabajo (90%, corresponden al estudio de ficoperifiton, el 10% restante incluyó ambos componentes del perifiton y se encontró una dedicada exclusivamente al zooperifiton. Sólo el 10,5% de las investigaciones (8 trabajos se han dedicado al estudio taxonómico detallado, el resto de publicaciones se orientan al estudio de la estructura y dinámica de la comunidad perifítica.

  6. Dos hipótesis sobre el presidencialismo autoritario

    Directory of Open Access Journals (Sweden)

    Soledad Loaeza

    2013-01-01

    Full Text Available El presidencialismo autoritario mexicano ha sido objeto de muchas reflexiones y opiniones. No obstante, se ha impuesto un paradigma presidencialista que privilegia la perspectiva personalizada e idiosincrática del ejercicio del poder, con un importante componente cultu- ralista. Aquí se propone, por una parte, una perspectiva histórica que contextualiza las accio- nes presidenciales en el período 1944-1970; por la otra, se parte de dos presupuestos generales. Uno, sostiene que los presidentes mexicanos actuaban bajo importantes restricciones y según los ritmos de un proceso que avanzó en episodios, más que en forma lineal o acumulativa; el otro destaca la limitación geopolítica que se deriva de la vecindad con Estados Unidos que incidió sobre las acciones presidenciales, pero también sobre el desarrollo institucional del país. La evolución del presidencialismo autoritario lleva la huella de esta influencia. Este artículo introduce elementos para la discusión de las hipótesis. La primera parte hace una revisión crítica del paradigma presidencialista; la segunda expone las restricciones que se derivaban de la vecindad con Estados Unidos. La tercera y última está dedicada a la descripción del tipo de episodios que Pueden servir para ilustrar la evolución del presidencialismo autoritario. Las dos hipótesis que aquí se presentan han guiado una investigación más amplia sobre el impacto de la Guerra Fría en México y el desarrollo del presidencialismo.

  7. Propuesta de programa educativo sobre enfermedades del cuello uterino

    Directory of Open Access Journals (Sweden)

    Grisel Mariela Mass Basulto

    2011-10-01

    Full Text Available Fundamento: El cáncer ginecológico está entre las más frecuentes causas de muerte en la población femenina. En Cuba, el diagnóstico precoz de tal afección está entre los programas priorizados del Sistema de Salud Pública; pero también es necesario enfatizar en la prevención, que puede lograse, sobre todo, desde la atención primaria de salud, mediante la implementación de programas educativos. Objetivo: Diseñar un programa educativo sobre afecciones del cuello uterino. Métodos: Estudio descriptivo y retrospectivo, en el período comprendido del 1 de enero de 2008 al 1 de enero de 2009. Se analizaron variables como edad, escolaridad, primeras relaciones sexuales, número de partos, número de compañeros sexuales, uso de anticonceptivo, antecedentes de infecciones de transmisión sexual, hábitos tóxicos y nivel de conocimiento. Se aplicó el criterio de expertos para la validación de la propuesta educativa. Resultados: La mayoría de las mujeres tuvieron relaciones sexuales precoces, cuatro o más compañeros sexuales y eran fumadoras, mientras que el total de ellas había presentado alguna vez infecciones vaginales. El nivel de conocimiento que predominó fue regular. Conclusiones: Es evidente que en la población estudiada se concentran varios factores de riesgo para el cáncer de cuello uterino. El Programa Educativo sobre enfermedades del cuello uterino, fue validado mediante criterio de expertos, los cuales coincidieron en que tiene gran actualidad científica, congruencia interna y en que favorece el proceso de preparación de la mujer para evitar ese tipo de enfermedades.

  8. Resúmenes de los trabajos sobre trastornos del movimiento

    Directory of Open Access Journals (Sweden)

    Congreso Nacional de Neurología

    2010-03-01

    Full Text Available En el salón sobre trastornos del movimiento se presentaron un total de 10 trabajos científicos en los cuales se destacó tanto la participación de autores nacionales como extranjeros. A continuación se pueden var en este apartado  los resúmenes de los artículos en el mismo orden que fueron presentados. También se puede encontrar en ellos las direcciones electrónicas de los responsables.

  9. Sobre nuevas miradas del peronismo y la prensa escrita

    OpenAIRE

    Ruvituso, Clara Inés

    2008-01-01

    Antes de que los académicos llenaran las numerosas páginas que almacena el debate sobre los orígenes y desarrollo del peronismo, la prensa fue uno de los ámbitos de producción de diferentes y dicotómicas representaciones, juicios y prejuicios respecto de la naturaleza y accionar del heterogéneo movimiento político liderado por Juan D. Perón. La compilación de artículos realizada por los historiadores Raanan Rein y Claudio Panella es una significativa contribución a la historia de la intrin...

  10. Sobre a bondade a partir da literatura do holocausto

    Directory of Open Access Journals (Sweden)

    Márcio Bruno Barra Valente

    2015-11-01

    Full Text Available Em termos filosóficos, a bondade é uma efetivação da possibilidade de homens e mulheres se colocarem em relações dialógicas autênticas, isto é, constituídas pela abertura e responsabilidade ética pelo Outro mesmo em situações de exceção. Este artigo objetiva construir uma proposta de investigação sobre a bondade a partir da literatura do holocausto.

  11. Bibliografía selecta sobre otros autores

    OpenAIRE

    Farré Vidal, Judith

    2013-01-01

    TC/12, Patrimonio teatral clásico español. Textos e instrumentos de investigación. Programa Consolider Ingenio CSD 2009-00033, es un macroproyecto de investigación sobre el teatro clásico español que ha sido seleccionado por el programa ministerial Consolider, la punta de lanza del Plan Nacional de I+D+i. El proyecto, con 12 equipos y más de 150 investigadores de 52 universidades y centros de investigación de todo el mundo, está coordinado por el catedrático de la Universitat de València Joan...

  12. Nota sobre el archivo de la familia Pardo Gil Taboada

    Directory of Open Access Journals (Sweden)

    Saurín de la Iglesia, María Rosa

    2007-12-01

    Full Text Available The intention of the bequest of the archives of Pardo Gil-Taboada to the Archive of the Kingdom of Galicia was that of establishing the genealogy of those who were the original source of such document. These notes attempt to sketch the profile of a noble family from they left the first traces of their existence, to well into the XX century. Going beyond the simple enumeration of individuals – “as if the nobility had no other function than the reproductive” – requires the addition of evidence about the way individuals behaved and collective traits and predispositions of the family group. Hence it is hoped that in future researchs this guide will facilitate and provide data about the formation of a family heritage and criteria on its administration, on the role played by women in the accumulation of wealth, attitudes towards life and the participacion by the nobility in the economic development of Galicia, and other aspects which may be of interest to both historians of sociology and economics.

    La donación del archivo Pardo Gil-Taboada al del Reino de Galicia requería establecer la genealogía de quienes originaron tales documentos. Estos apuntes intentan trazar el perfil de una familia hidalga desde que empezó a dejar señales de su existencia hasta bien entrado el siglo XX. Superar la simple enumeración de personas - “como si la nobleza no hubiera tenido más función que la reproductora”, en palabras de Domínguez Ortiz – suponía añadir indicaciones sobre comportamientos individuales y tendencias colectivas del grupo familiar y eso es lo que se ofrece aquí sinteticamente, como una guía de urgencia que anuncie a futuros investigadores lo que podrán hallar en esta documentación: datos sobre la formación de un patrimonio familiar y sobre los criterios de administrarlo, sobre el papel de las mujeres en la acumulación de bienes, actitudes ante la vida, participación de la hidalguía en el crecimiento económico de

  13. Antioxidantes de origen vegetal. Efecto sobre el envejecimiento

    OpenAIRE

    Descalzo Perea, Virginia

    2016-01-01

    Este trabajo consiste en una revisión bibliográfica sobre diferentes tipos de antioxidantes de origen vegetal que podemos encontrar en los alimentos, así como sus características y efectos principales. Los radicales libres más frecuentes son los derivados del oxígeno y se producen como consecuencia de las reacciones de oxidación, que constituyen una parte esencial del metabolismo. Cuando la producción de radicales libres excede a la defensa antioxidante se da un desequilibrio y, como consecue...

  14. Ferropenia: impacto sobre el estado de salud mental

    OpenAIRE

    Sánchez Jiménez, Apolonia

    2015-01-01

    La deficiencia de hierro y la anemia por déficit del mismo, son trastornos nutricionales y hematológicos frecuentes en el mundo y afectan a una población estimada de 2.000.000 de personas. La deficiencia de hierro tiene efectos adversos sobre la actividad de numerosas enzimas y en bebés pueden provocar alteraciones del crecimiento y del desarrollo intelectual. Los aspectos hematológicos de la deficiencia de hierro no son específicos, y con demasiada frecuencia se confunden con otras causas d...

  15. Percepções da elite sobre pobreza e desigualdade

    OpenAIRE

    Reis Elisa P.

    2000-01-01

    O artigo analisa a visão de setores da elite brasileira sobre a pobreza e a desigualdade. Com base no argumento de que as percepções daqueles que comandam recursos estratégicos afetam diretamente a formulação e implementação de políticas sociais, e amparada por alguns estudos pioneiros realizados na Europa e nos Estados Unidos, a autora se propõe a investigar como as conseqüências da pobreza e da desigualdade são vistas fora do mundo dos pobres. A partir de dados de survey, entrevistas em pro...

  16. Actualizaciones sobre declaraciones nutricionales y de propiedades saludables

    OpenAIRE

    Perales Albert, Alejandro; Bernácer Martínez, Raquel; García Gómez, Julián; Álvarez-Dardet Díaz, Carlos; Ortiz Moncada, Rocío

    2013-01-01

    Existe preocupación por la influencia de los determinantes sociales relacionados con la publicidad, la comunicación y la información sobre la selección de productos alimenticios para conseguir una alimentación saludable y segura. Desde este punto de vista, la legislación española normaliza este aspecto, a través del Reglamento Europeo 1924/2006 (RE1924/2006). El objetivo es asegurar y favorecer el acceso a alimentos inocuos que beneficien la salud y, evitar que la información recibida por los...

  17. Reflexiones Sobre el Contrato en el Derecho Colombiano

    OpenAIRE

    Vargas-Chaves, Ivan

    2015-01-01

    Spanish Abstract: En este capítulo de libro se realiza una aproximación al contrato en el derecho colombiano, a través de una guía de estudio que abarca su conceptualización doctrinal. Ello con el fin de motivar el interés para los estudiosos y estudiantes del derecho comparado iberoamericano, quienes son los destinatarios finales del libro que tiene por título: Reflexiones sobre Derecho Privado Patrimonial (Universidad de Salamanca, 2015). English Abstract: This book chapter makes an approac...

  18. Sobre espacios y álgebras de funciones holomorfas

    OpenAIRE

    Sevilla Peris, Pablo

    2001-01-01

    RESUMEN La Tesis Sobre espacios y ´algebras de funciones holomorfas se estructura en tres cap´ýtulos diferentes. En cada uno de ellos se aborda un problema diferente. El primer cap´ýtulo se dedica al estudio de los operadores de composici´on. La idea original es bastante sencilla y natural. Tomamos el disco unidad complejo, que denotamos D, y una funci´on holomorfa : D −! D. Con esto se define un operador f 7! f donde f : D −! C es una funci´on holomorfa. Consideramos el cas...

  19. Algunas reflexiones metodológicas sobre la Historia Constitucional

    OpenAIRE

    Varela Suanzes-Carpegna, Joaquín Victoriano

    2007-01-01

    En este artículo defino la Historia Constitucional como una rama de la Historia, de marcado contenido jurídico, que se ocupa de la génesis y desarrollo del Estado liberal y liberal-democrático, de acuerdo con un concepto axiológico de Constitución. Conforme a esta definición abordo algun o de los problemas que plantea el estudio histórico de las normas y de las instituciones, así como sobre todo de las doctrinas y de los conceptos constitucionales. A este respecto, insisto en la necesidad de ...

  20. Estudio sobre la presencia de Legionella en agua sanitaria

    OpenAIRE

    Bonet Ivars, Verónica

    2012-01-01

    RESUM: Estudi sobre la variabilitat de la legionel·losi en funció del tamany de la mostra. L'objectiu és, d'una banda, estudiar la presència i concentracions de Legionella a diversos hospitals durant un any, i per un altre, demostrar la variabilitat de l'inòcul segons els punts de mostreig recollits en aquests hospitals. El resultat ha estat que tots els hospitals testats estaven colonitzats per Legionella encara que els inòculs han variat durant un mateix mostreig i amb diferents mostrejos e...

  1. Estudio sobre el bruxismo y una nueva prueba de esfuerzo

    OpenAIRE

    Hernández Aliaga, Manuel

    2010-01-01

    Actualmente en la literatura encontramos cientos de publicaciones sobre etiología, efectos y tratamiento del bruxismo, sin embargo no están claros los criterios diagnósticos aplicados para etiquetar a una persona de bruxista. Sería deseable hallar nuevos signos de diagnóstico de bruxismo menos alejados de la incertidumbre, con la que conviven mal los clínicos. En nuestro trabajo hemos determinado unos signos patológicos a nivel dentario y muscular como criterios de diagnóstico de bruxismo, ad...

  2. Notas sobre tres especies de Gigartinaceae (Rhodophyta del litoral peruano

    Directory of Open Access Journals (Sweden)

    Martha Calderón

    2011-05-01

    Full Text Available La gran variabilidad morfológica de la familia Gigartinaceae ha producido constantes cambios taxonómicos en sus especies miembros. Tradicionalmente su taxonomía ha estado basada en caracteres de la morfología externa; sin embargo, recientes estudios morfológicos, respaldados con trabajos moleculares, han delimitado los géneros en base a al desarrollo del cistocarpo y de los tetrasporangios. El presente trabajo revisa y comenta sobre las estructuras morfológicas vegetativas y reproductivas de tres especies presentes en Perú: Chondracanthus chamissoi, Mazzaella denticulata y Chondrus canaliculatus.

  3. Ensayos sobre la sonrisa de volatilidad en mercados de opciones

    OpenAIRE

    Serna Calvo, Gregorio

    2000-01-01

    La tesis comienza analizando los determinantes de la "sonrisa de volatilidad" en el mercado de opciones sobre el indice IBEX-35,obteniendose evidencia de causalidad lineal en el sentido de Granger de los costes de transacción, representados por el diferencial "bid-ask" relativo, ala forma de la sonrisa. A continuación, se propone un modelo de Black-Scholes ampliando donde la volatilidad depende del precio de ejercicio y del diferencial "bid-ask" relativo, obteniendose que dicho modelo no mejo...

  4. Anotaciones sobre la escritura de lo político

    Directory of Open Access Journals (Sweden)

    Markus Schultze-Kraft

    2009-06-01

    Full Text Available Escribir bien sobre lo político es una forma de arte. Hoy, pocos escritores entienden el significado de esta premisa. Constantemente nos enfrentamos a artículos, ensayos, informes y libros mediocres y sesgados que pretenden ser “políticos” y “científicos”, pero que en realidad son expresiones de sensacionalismo y confusión ideológica o de falta de conocimiento empírico del autor, y generalmente de perspectiva.

  5. ESTUDIO SOBRE LA PERCEPCIONES Y LA EDUCACIÓN AMBIENTAL

    OpenAIRE

    Raúl Calixto Flores; Lucila Herrera Reyes

    2010-01-01

    La educación ambiental como un campo emergente de construcción de nuevas propuestas, demanda de otros campos de estudio, información para comprender el origen de los comportamientos ambientales desfavorables hacia el medio ambiente. Se asume que la forma en que la persona percibe y construye los problemas ambientales, no se sustenta, necesariamente, en una forma neutral de contemplar el mundo; estas percepciones y los sesgos que las llevan a privilegiar ciertos problemas por sobre otros con d...

  6. Desenvolvimento da Tanatologia: estudos sobre a morte e o morrer

    OpenAIRE

    Maria Julia Kovács

    2008-01-01

    Este artigo discute os principais temas e pesquisas na área da Tanatologia, estudos sobre a morte e o morrer. São apresentados os autores pioneiros que escreveram as primeiras obras de sistematização da Tanatologia entre os quais: Herman Feifel, Robert Kastenbaum e Elizabeth Kübler-Ross, e os principais temas de estudo: luto, violência e guerra, a morte e a TV, cuidados a pacientes gravemente enfermos, além da formação de profissionais da área de saúde e educação para lidar com pessoas vivend...

  7. Sobre la industria ósea de Altamira

    OpenAIRE

    Giménez la Rosa, Marta; Cabrera Valdés, Victoria

    1991-01-01

    Las últimas excavaciones en Altamira ofrecen cierta luz sobre el yacimiento y la probabilidad de interpretaciones que hasta el momento implicaban dificultades en cuanto a la atribución de industria. Con las dos referencias publicadas que ya existen (FREEMAN, L. G., 1988 y GONZÁLEZ ECHEGARAY, J., 1988) esta aportación se suma para completar en lo posible la visión del yacimiento desde el apartado de la industria ósea, con el estudio de la serie de piezas que se obtuvieron en ...

  8. Sobre el presente de la Arqueología Púnica

    Directory of Open Access Journals (Sweden)

    Miquel TARRADELL

    2009-10-01

    Full Text Available Notas sobre un viaje a Túnez y Argelia podría titularse también este articulo. En efecto, la información que puede dar y las novedades que para los investigadores que trabajan en el ámbitoi arqueológico peninsular en él se contienen son debidas en gran parte a la estancia que en la primavera de 1951 he podido hacer en estos territorios, aparte de la aportación respecto a Marruecos, fruto de mis propias excavaciones.

  9. Confianza como consecuencia del compromiso percibido: Implicaciones sobre el aprendizaje y la innovación

    OpenAIRE

    García Cruz, Joaquín; Real Fernández, Juan Carlos

    2013-01-01

    En este trabajo pretendemos alcanzar un doble objetivo. En primer lugar, estudiamos la influencia del compromiso afectivo de los empleados percibido por el directivo, tanto sobre su nivel de confianza, como sobre la capacidad de aprendizaje organizativo (CAO). Igualmente, analizamos cómo influye sobre la CAO esta predisposición del directivo a confiar en sus empleados. En segundo lugar, examinamos si el compromiso afectivo de los empleados percibido por el directivo, la confianza del directiv...

  10. Preparation and thermoelectric properties of M0.05Ca0.95MnO3%M0.05Ca0.95MnO3的制备及其热电性能

    Institute of Scientific and Technical Information of China (English)

    许洁; 魏长平; 贾坤

    2011-01-01

    采用溶胶-凝胶法,以硝酸盐为原料,在常压空气气氛中于1 000℃烧结8 h制备出CaMnO3和M0.05Ca0.95MnO3(M=Sr2+,Sm3+)块体材料。利用X线衍射、扫描电子显微镜等研究材料的物相和微观形貌,考察Sr2+和Sm3+M+掺杂对CaMnO3的高温热电性能参数Seebeck系数、电阻率和功率因子的影响。研究结果表明:制备的样品具有单一的物相,结构致密;金属离子Sr2+和Sm3+掺杂可以有效地改善其热电性能;当Sm3+的掺杂量为0.05时可获得最佳的热电性能,600℃时功率因子为23×10-5W·m-1·K-2。%CaMnO3 and M0.05Ca0.95MnO3 (M=Sr2+, Sm3+) samples were synthesized by sol-gel method and sintered in air at 1 000 "C for 8 h with nitrates as starting materials. The phase composition and microstructure were studied by XRD and SEM. Thermoelectric properties such as the Seebeck coefficient, electrical resistivity and power factor of M0.05Ca0.95MnO3 samples were studied. The results show that theM0.05Ca0.95MnO3 samples have single phase and condensed microstructure. The samples substituted by metal ions(Sr2+, Sm3+) enhance the electrical transmission performance effectively, and the highest power factor is 23×10-5 W·m-1·K-2 at 600 ℃ for the sample of Sm0.05Ca0.95MnO3.

  11. Clinical observation of 3M polyester foam dressing for bedsore intervention%3M聚酯泡沫敷料用于压疮高危患者的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    黄菊; 何功永

    2014-01-01

    Objective To investigate the prevention effect of 3M polyester foam dressing for patients with high risk of bedsore. Methods Made 240 cases of patients with high risk of bedsore as the object of study, 160 patients using 3M polyester foam dressing intervention as the dressing group, and collected 80 cases using the traditional method of intervention patients as control. Results the incidence of bedsore in dressing group were 11.3% (18/160), which was significantly lower than the control group 46.3% (37/80), the differences of the bedsore rate, efficacy and the total efficiency in two groups were statistically significant (P<0.05).Conclusion Using 3M polyester foam dressing in the prevention of high-risk bedsore patients, bedsore rate is low, effect is significant, which worthy of further clinical use.%目的:探讨3M聚酯泡沫敷料对压疮高危患者的预防效果。方法以240例压疮高危患者作为研究对象,160例用3M聚酯泡沫敷料进行干预为敷料组,80例采用传统方法干预患者为对照组。结果敷料组患者中压疮发生率11.3%(18/160),明显低于对照组的46.3%(37/80),2组压疮发生率、以及总有效率比较差异均有统计学意义(P<0.05)。结论对高危压疮患者应用3M聚酯泡沫敷料进行压疮预防,压疮发生率低,疗效显著,值得临床推广使用。

  12. Socialismo y peronismo en la historiografía sobre el Partido Socialista

    OpenAIRE

    Silvana Ferreyra

    2011-01-01

    Este artículo es un estado de la cuestión sobre el lugar del peronismo en la historiografía sobre el socialismo en la Argentina. Por un lado, analizamos cómo influyó el peronismo en la formulación de los interrogantes que guiaron las investigaciones sobre la historia del Partido Socialista. A tal efecto nos detendremos en los trabajos del revisionismo de izquierda, la historiografía de la transición democrática y el campo de estudio sobre la historia de la izquierda. A continuación analizamos...

  13. Apuntes para un debate sobre el impacto cognoscitivo de la televisión

    OpenAIRE

    Orozco-Gómez, Guillermo

    1986-01-01

    Artículo que presenta un análisis sobre el impacto cognoscitivo de la televisión y que sustenta la tesis de que la falta de conocimiento sobre el impacto negativo de este medio es consecuencia de la forma en que los investigadores han abordado el tema. Se habla sobre el libro “Mind and media. The effects of TV, videogames and computers” de Patricia Marks Greenfield, como un buen ejemplo del paradigma de investigación dominante, y porque es uno de los primeros intentos de estudio sobre los efe...

  14. Reflexiones sobre los medios de comunicación de masas en la Europa moderna

    OpenAIRE

    Burke, Peter

    2005-01-01

    Este artículo muestra las reflexiones que Peter Burke se hace sobre los últimos estudios y la más reciente bibliografía aparecidos tras la publicación del libro De Gutenberg a Internet: Una historia social de los medios de comunicación, escrito por el propio Burke y A. Briggs sobre este tema. Sus reflexiones se centran y tratan la comunicación oral, los manuscritos, el debate Eisenstein sobre la revolución de la imprenta y sus consecuencias y la polémica Habermas sobre la esfera pública. Adem...

  15. El punzante pasado : sobre arte, historia y memoria en el estado español

    OpenAIRE

    Vicente Aliaga, Juan

    2012-01-01

    En el texto se plantea la pregunta, y se trata de ofrecer algunas respuestas, sobre la ausencia durante muchos años de trabajos artísticos surgidos en el estado español sobre el pasado histórico, y concretamente sobre el periodo de la II República, la guerra civil y la dictadura franquista. Asimismo se propone una reflexión sobre la amnesia generada en la etapa de la transición a la democracia tras la muerte de Franco. Se estudian distintas propuestas artísticas que han abordado desde finales...

  16. Intervenção sobre intervenção: sobre a transferência em um trabalho social

    Directory of Open Access Journals (Sweden)

    Fabio Azeredo

    2014-05-01

    Full Text Available Este trabalho visa a refletir sobre a relação de trabalho estabelecida entre a família assistida pelo Projeto de Reinserção Familiar (PRF, junto à Fundação para a Infância e Adolescência (FIA, e a equipe técnica de um dispositivo de atenção diária para pessoas com deficiência. Será feita uma exposição da nossa intervenção sobre a intervenção da referida equipe. O PRF destina-se a crianças e adolescentes portadores de necessidades especiais institucionalizados, realizando um acompanhamento psicossocial sistemático aos familiares dos mesmos, mediante visitas domiciliares e contatos de rede, que residem em comunidades carentes do estado do Rio de Janeiro. Um caso será relatado à luz da nossa linha de pesquisa, intitulada A pobreza como direito à exceção. O texto Intervenção sobre a transferência, do psicanalista Jacques Lacan, será utilizado para explicitar as peculiaridades de uma intervenção de orientação psicanalítica em oposição a uma intervenção de cunho assistencialista. Ademais, utilizar-se-á a discussão que o sociólogo francês Serge Paugam propõe no texto A desqualificação social, no intuito de ressaltar as principais diferenças entre a intervenção realizada por uma equipe de trabalhadores sociais e a nossa intervenção, calcada na interpretação psicanalítica, não só junto à família assistida como junto a esta equipe.

  17. Descontruindo mapas, revelando espacializações: reflexões sobre o uso da cartografia em estudos sobre o Brasil colonial

    OpenAIRE

    Tiago Kramer de Oliveira

    2014-01-01

    O artigo discute o uso da cartografia em estudos históricos com base em obras recentes no campo da Cartografia Histórica e da História da Cartografia, em particular nas pesquisas sobre o Brasil Colonial. Na primeira parte refletimos sobre o uso de ferramentas digitais em estudos de cartografia histórica. Na segunda, discutimos algumas definições sobre a "natureza dos mapas" e suas implicações teóricas e metodológicas. Por fim, fazemos um pequeno exercício de interpretação com base em um fragm...

  18. Synthesis and characterization of aluminum and gallium complexes of heterocyclic thiosemicarbazones. crystal structures of Me{sub 2}M[SC{sub 4}H{sub 3}CHNNC(S)SCH{sub 3}] (M=Al, Ga)

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Young Jin; Yoo, Byung Woo; Kang, Sang Ook; Ko, Jae Jung [Korea Univ., Chochiwon (Korea, Republic of); Kang, Seung Joo [Korea National University of Education, Chongwon (Korea, Republic of)

    1998-01-01

    The synthesis and characterization of the monomeric group 13 heterocyclic thiosemicarbazone complexes Me{sub 2}M[SC{sub 4}H{sub 3}CHNNC(S)SCH{sub 3}] (M=Al (2), Ga (3)) are described. Compounds 2-3 were prepared using MMe{sub 3} (M=Al, Ga) in toluene with 2-thiophenecarboxaldehyde-S-methyldithiocarbazate under anaerobic conditions. These complexes have been characterized by {sup 1}H NMR, {sup 13}C NMR, elemental analyses, and single-crystal X-ray diffraction. 2 crystallizes in the monoclinic space group P2{sub 1}/c with unit cell parameters a=10.2930(5) A, b=18.564 (1) A, c=7.3812(6) A, V=1347.9(2) A{sup 3}, D{sub calc}=1.342 gcm{sup -3} for Z=4, 9281 reflections with I<3{sigma} (I), R1=0.0500 and wR2=0.0526. 3 crystallizes in the orthorhombic space group P{sub bca} with unit cell parameters a=13.340(3) A, b=19.9070(5) A, c=11.3690(2) A, V=2673.88(9) A{sup 3}, D{sub calc}=1.511 gcm{sup -3} for Z=8, 17004 reflections with I>3{sigma}(I), R1=0.0480 and wR2=0.0524. Compound 3 is a monomeric gallium compound with a weak interaction between the pendant thiophene and the gallium center.

  19. Expression of RFamide-Related Peptide-3 (RFRP-3) mRNA in Dorsomedial Hypothalamic Nucleus and KiSS-1 mRNA in Arcuate Nucleus of Rat during Pregnancy

    Science.gov (United States)

    Sabet Sarvestani, Fatemeh; Tamadon, Amin; Koohi-Hosseinabadi, Omid; Mohammadi Nezhad, Saeed; Rahmanifar, Farhad; Jafarzadeh Shirazi, Mohammad Reza; Tanideh, Nader; Moghadam, Ali; Niazi, Ali

    2014-01-01

    Background RFamide-related peptide-3 (RFRP-3) and kisspeptin (KiSS-1) are known to respectively inhibit and stimulate gonadotropin releasing hormone (GnRH) and lute- inizing hormone (LH) secretion in rat. The aim of the present study was to evaluate the relative mRNA expression of RFRP-3 and KiSS-1 in the hypothalamus of pregnant rats. Materials and Methods In a randomized controlled experimental study, the exact preg- nancy day of 18 Sprague-Dawley rats were confirmed using the vaginal smear method and were equally assigned to three groups of days 7, 14 and 21 of pregnancy. Four non- pregnant female rats were ovariectomized and assigned as the control group. All rats were decapitated, and the dorsomedial hypothalamic nucleus (DMH) and the arcuate nucleus (ARC) for detection of KiSS-1 mRNA were separated from their hypothalamus to detect RFRP-3 and KiSS-1 mRNA respectively. Then, their relative expressions were compared between control and pregnant groups using real-time polymerase chain reac- tion (PCR). Results The relative expression of RFRP-3 mRNA in DMH did not change significantly during pregnancy (p>0.01). However, the relative expression of KiSS-1 mRNA in ARC was at its highest in day 7 of pregnancy and decreased until day 21 of pregnancy (p<0.01). Conclusion Decrease in GnRH and LH secretion during the pregnancy of rat may be controlled by constant expression of RFRP-3 mRNA and reduced expression of KiSS-1 mRNA in hypothalamus. PMID:25379163

  20. Tungsten bronze-based nuclear waste form ceramics. Part 3: The system Cs 0.3M xW 1- xO 3 for the immobilization of radio cesium

    Science.gov (United States)

    Luca, Vittorio; Drabarek, Elizabeth; Chronis, Harriet; McLeod, Terry

    2006-11-01

    Previous studies in this series have indicated that Cs- and Sr-loaded Mo-doped hexagonal tungsten bronze (MoW-HTB) oxides, either in the form of fine grained powders, or as composite granules, can be converted to leach resistant ceramics at modest temperatures in the range 600-1200 °C. In the present study it has been shown that such waste form ceramics can also be readily prepared through very simple conventional routes involving the blending of cesium nitrate with tungstic acid and other oxide components followed by heating in air. The phase chemistry resulting from the blending of these oxides has been explored. In the Cs 0.3M xW 1- xO 3 compositional system where x = Ti, Zr, Nb and Ta the solid solution limit has been found to be where x = 0.2. For all values of x between 0 and 0.2 mixed phase materials of HTB and WO 3 were obtained and Cs was found associated with HTB phases that are both rich and depleted in M element. At temperatures above about 1000 °C, phase pure HTB compounds in the space group P63/ mcm were obtained. Even when x greatly exceeds 0.2, the additional oxide content did not interfere with the formation of the HTB phase. Durability of the Cs 0.3M xW 1- xO 3 compositions as gauged by the fractional Cs loss in de-mineralized water was lowest when M = Ti and Nb, and greatest when M = Zr. From these results the durability appears intimately linked with the unit cell a-dimension which in turn varies with M cation radius.

  1. Heterotetranuclear oxalato-bridged Re(IV)3M(II) (M = Mn, Fe, Co, Ni, Cu) complexes: a new example of a single-molecule magnet (M = Ni).

    Science.gov (United States)

    Martínez-Lillo, José; Armentano, Donatella; De Munno, Giovanni; Wernsdorfer, Wolfgang; Clemente-Juan, Juan Modesto; Krzystek, J; Lloret, Francesc; Julve, Miguel; Faus, Juan

    2009-04-01

    The use of the mononuclear species (NBu(4))(2)[Re(IV)Cl(4)(ox)] (NBu(4)(+) = tetra-n-butylammonium cation; ox = oxalate dianion) as a ligand toward fully solvated divalent first-row transition-metal ions affords the tetranuclear complexes (NBu(4))(4)[{Re(IV)Cl(4)(mu-ox)}(3)M(II)] with M = Mn (1), Fe (2), Co (3), Ni (4), and Cu (5). Their structure is made up of discrete [{ReCl(4)(mu-ox)}(3)M](4-) anions and bulky NBu(4)(+) cations. The complexes 2-5 crystallize in the triclinic system with space group P1; 2 and 5 as well as 3 and 4 are isostructural. The Re and M atoms exhibit somewhat distorted ReCl(4)O(2) and MO(6) octahedral surroundings, with the oxalate groups adopting the bis-bidentate bridging mode. Magnetic susceptibility measurements on polycrystalline samples of 1-5 in the temperature range 1.9-300 K show the occurrence of intramolecular antiferromagnetic [J = -1.30 cm(-1) (1)] and ferromagnetic couplings [J = +1.62 (2), +3.0 (3), +16.3 (4), and +4.64 cm(-1) (5)], with the Hamiltonian being defined as H = -J[S(M)(S(Re1) + S(Re2) + S(Re3))]. Compound 4 is the first example of an oxalato-bridged heterometallic species that behaves as a single-molecule magnet with a ground-state spin S = (11)/(2) and D = -0.8(1) cm(-1), as shown by the study of its static and dynamic magnetic properties and a high-frequency electron paramagnetic resonance study on polycrystalline samples together with detailed micro-SQUID measurements on single crystals.

  2. Expression of RFamide-Related Peptide-3 (RFRP-3 mRNA in Dorsomedial Hypothalamic Nucleus and KiSS-1 mRNA in Arcuate Nucleus of Rat during Pregnancy

    Directory of Open Access Journals (Sweden)

    Fatemeh Sabet Sarvestani

    2014-11-01

    Full Text Available Background: RFamide-related peptide-3 (RFRP-3 and kisspeptin (KiSS-1 are known to respectively inhibit and stimulate gonadotropin releasing hormone (GnRH and luteinizing hormone (LH secretion in rat. The aim of the present study was to evaluate the relative mRNA expression of RFRP-3 and KiSS-1 in the hypothalamus of pregnant rats. Materials and Methods: In a randomized controlled experimental study, the exact pregnancy day of 18 Sprague-Dawley rats were confirmed using the vaginal smear method and were equally assigned to three groups of days 7, 14 and 21 of pregnancy. Four nonpregnant female rats were ovariectomized and assigned as the control group. All rats were decapitated, and the dorsomedial hypothalamic nucleus (DMH and the arcuate nucleus (ARC for detection of KiSS-1 mRNA were separated from their hypothalamus to detect RFRP-3 and KiSS-1 mRNA respectively. Then, their relative expressions were compared between control and pregnant groups using real-time polymerase chain reaction (PCR. Results: The relative expression of RFRP-3 mRNA in DMH did not change significantly during pregnancy (p>0.01. However, the relative expression of KiSS-1 mRNA in ARC was at its highest in day 7 of pregnancy and decreased until day 21 of pregnancy (p<0.01. Conclusion: Decrease in GnRH and LH secretion during the pregnancy of rat may be controlled by constant expression of RFRP-3 mRNA and reduced expression of KiSS-1 mRNA in hypothalamus.

  3. sobre o que aprendem com a tevê

    Directory of Open Access Journals (Sweden)

    Rosália Duarte

    2006-01-01

    Full Text Available Este artículo presenta los resultados de una encuesta realizada por el Grupo de Pesquisa en Educación y Medios de Comunicación, de la Pontificia Universidad Católica de Río de Janeiro (PUC-Río, en 2004, que tuvo como objetivo describir y comprender las relaciones que los niños establecen con la televisión, desde el punto de vista de ellos. El estudio tuvo como soporte empírico textos escritos por más de cuatrocientos niños de la Región Sudeste, con edades entre 8 y 12 años, en los que ellos expresan lo que piensan sobre lo que ven en la tele. Los procedimientos analíticos de los textos de los niños fueron estructurados a partir de ejes temáticos extraídos de los mismos. Este artículo privilegia el tema “lo que los niños piensan sobre lo que aprenden con la tele”.

  4. "Encontrando Bianca": discursos sobre o corpo-travesti

    Directory of Open Access Journals (Sweden)

    Nilson Fernandes Dinis

    2014-08-01

    Full Text Available Este artigo objetiva realizar uma análise dos discursos produzidos sobre o corpo travesti em um vídeo educativo. Toma-se como corpus de análise o vídeo: "Encontrando Bianca", que narra uma história fictícia sobre os dilemas de uma travesti na escola em que estuda. Esse vídeo compõe parte do material educativo Kit anti-homofobia. Faz-se como opção metodológica trabalhar a partir da arqueogenealogia foucaultiana, uma vez que esse acontecimento se insere numa ordem de saber e poder. A conclusão é de que o vídeo, constituindo-se como uma produção discursiva, pode, no lugar de realizar seu propósito de combate à homofobia, apresentar um poder ressurgido que aprisiona o corpo a um discurso ideal e cria um corpo idealizado para as travestis.

  5. Precisiones sobre la luz en el Pantheon de Roma

    Directory of Open Access Journals (Sweden)

    Oscar Linares de la Torre

    2015-04-01

    Full Text Available El Pantheon de Adriano es una de las obras más celebradas de la historia de la arquitectura. Han sido muchas las cuestiones que han cautivado a cuantos han entrado en él, pero es la luz la que ha acaparado el mayor protagonismo: una vez despojado el edificio de su originaria carga simbólica, la manifestación de su luz interior parece ser el único fin de este inmenso espacio-luz que tanto ha fascinado a arquitectos, historiadores del arte, pintores y fotógrafos. Parece difícil poder aportar nada nuevo. Consciente de ello, el autor del presente artículo sólo pretende apuntar algunas cuestiones sobre distintos aspectos de la luz en el Pantheon que considera que no han sido aún suficientemente desarrolladas: el por qué de la orientación solar y urbana del templo con respecto al eje norte-sur; la reconstrucción de la secuencia de luz y sombra que debió de darse en el recorrido original de acceso al interior del templo; la interpretación del haz de luz ocular como reminiscencia inmaterial del soporte central de las falsas cúpulas etruscas, convertida en una columna de materia sutil que, sin alcanzar nunca la vertical, incide de manera variada sobre los paramentos que conforman el interior.

  6. Familias reconstituidas: Un estudio sobre las nuevas estructuras familiares

    Directory of Open Access Journals (Sweden)

    ISABEL ESPINAR FELLMANN

    2003-01-01

    Full Text Available En la mayoría de las investigaciones sobre la familia, los estudios se han centrado en las familias intactas o primeras familias. Sin embargo, es cada vez mayor el número de familias cuya configuración incluye un segundo matrimonio e hijos de una unión anterior (i.e. familias reconstituidas. En la consolidación del complejo proceso de ajuste de estas familias se han identificado unas fuentes comunes de estrés relacionadas principalmente con la formación de un nuevo sistema familiar. El objetivo de este artículo es realizar una revisión de las variables que inciden en el bienestar y/o malestar psicológico sobre una muestra de padrastros y madrastras españoles en el seno de estas nuevas configuraciones familiares. En una primera fase se realizaron, desde un diseño cualitativo, 20 entrevistas en profundidad a una muestra de padrastros y madrastras. En una segunda fase, se diseñó un cuestionario que fue respondido por 77 sujetos con la finalidad de analizar la posible relación entre alguna de las variables estudiadas.

  7. La undécima tesis de Marx sobre Feuerbach

    Directory of Open Access Journals (Sweden)

    Federico Camino Macedo

    1993-06-01

    Full Text Available El artículo pretende ser una reflexión libre sobre la legitimidad de la exigencia a la filosofía formulada en la undécima tesis de Marx sobre Feuerbach. Esta, sin embargo,se refiere a un grupo determinado y a una manera de entender la filosofía, los neohegelianos llamados de izquierda y su concepción de la crítica, así como a Feuerbache inclusive a Hegel. Es en este contexto filosófico que hay que entenderla. Pese ala contraposición entre interpretación y tranformación que la tesis parece sugerir,el autor desarrolla la idea de que la unidadestá dada por el hombre que interpreta cosas,las ordena en teorías y actúa en el mundo.De allí que si se le pide a la filosofía que transforme el mundo se extralimita su poder,pero sin ella toda transformación es impensable

  8. A etnografia das ruas: notas sobre estudar e ser estudado

    Directory of Open Access Journals (Sweden)

    Hecht, Tobias

    2002-01-01

    Full Text Available Passeando entre as notas e as lembranças de dois períodos distintos de trabalho de campo, este ensaio "impressionista" trata da dinâmica em mudança de uma relação de pesquisa com crianças de rua. Em 1992-1993, conduzi trabalho de campo para uma dissertação sobre crianças de rua no nordeste brasileiro. Retornando à região seis anos mais tarde, descobri que a maioria das crianças estudadas apenas uma fração de geração antes estavam então mortas. Estas anotações enfocam minhas conversas com um dos sobreviventes e com quem (e sobre quem estou agora escrevendo uma biografia. Esse esforço colaborativo, voltado de certo modo a reconsiderar as implicações éticas da pesquisa com crianças que levam vidas violentas e vulneráveis, levanta uma gama de novos desafios éticos, alguns dos quais inteiramente imprevistos

  9. Nuevas reflexiones sobre la Posgerontología

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    Ricardo Iacub

    2014-03-01

    Full Text Available La Posgerontología plantea una lectura epistemológica, crítica y política sobre los relatos con los que se construye el envejecimiento y la vejez desde la gerontología. En este artículo se analizará crítica y políticamente a la gerontología, tanto como un objeto cultural exótico - por su pretensión omnicomprensiva -, como por ser un campo de conocimientos cuyos presupuestos explícitos e implícitos inciden sobre su objeto de estudio. Estos factores ponen en consideración los ajustes que debe realizar todo campo de conocimiento frente a los cambios que le imprime el contexto. Así como también expresan la necesidad de dar cuenta de los efectos de la realidad que construyen en las diversas formas de saber y en las prácticas sociales.

  10. Movimientos correctos a la velocidad correcta sobre los ciclos correctos

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Mejía Q.

    2006-05-01

    Full Text Available El propósito del estudio fue explicar cómo una pequeña empresa colombiana compite en el mercado de telecomunicaciones de Estados Unidos. Esto fue posible usando el modelo de la Doble Hélice de Fine, que muestra los ciclos estructurales de cambios tecnológicos, sobre los que la compañía tuvo que tomar las decisiones estratégicas correctas para seguir la dinámica sectorial a la velocidad correcta. El estudio de caso consistió en una síntesis histórica sectorial y de la empresa, incluyendo hitos claves, después, la velocidad fue medida y finalmente una decisión fue recomendada para poder sobrevivir sobre el patrón de movimientos y cambios sectoriales. / The purpose of this study was to explain how a little Colombian company competes in the dynamic US telecomm market. It was possible by using Fine´s Double Helix Model that shows two structural cycles to explain technological movements, in each cycle, the company studied had to do the correct strategic decisions to follow the industrial dynamics at the right clockspeed. The case study consisted of an industrial and a company historical synthesis, including key issues, afterwards, clockspeed is measured and finally a decision is recommended to survive on the pattern of industrial changes and movements.

  11. Puente sobre el río Severn – Inglaterra

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1970-09-01

    Full Text Available The bridge described in this article has solved the increasing traffic problem in the South West of Wales. The total project involves the suspension bridge itself, a second bridge over the river Wye, and a 10 span metal viaduct, which joins both bridges, and runs over the Beachley peninsula. The suspension bridge is outstanding because of its main towers and the compact construction of the main deck, as well as for the oblique positioning of the secondary cables.El puente que se describe en el artículo ha venido a resolver el problema del tráfico creciente en el SO. del País de Gales. La obra completa comprende: el puente colgante propiamente dicho, otro puente sobre el río Wye y un viaducto metálico, de 10 tramos, que une a ambos, sobre la península de Beachley. Se trata de una solución muy interesante, por sus torres de suspensión, por la construcción compacta de su tablero y por la disposición oblicua de los cables, entre otros detalles.

  12. Códigos de linguagem no discurso sobre o cinema

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    Rosemari Fagás Viégas

    2014-01-01

    Full Text Available Este trabalho consiste em um estudo sobre os códigos da linguagem cinematográfica a partir de seus significados estético, psicológico e sociológico. Adotam-se como pontos de vista teóricos a divisão tricotômica dos signos proposta por Charles S. Peirce, a revisão crítica da Teoria da Imagem, a descrição de Walter Benjamin sobre a natureza política inerente aos processos técnicos de produção fílmica e a hipótese de que as respostas às questões apontadas pela análise do cinema, realizada por Christian Metz, dependem da solução de problemas lógicos da construção de classes de significação dentro da semiótica. O método utilizado é tanto o bibliográfico quanto aquele baseado em análise de filmografia selecionada. O trabalho procura explicitar a nova classe de signos e de representações que a linguagem digital do cinema deverá produzir no futuro próximo.

  13. Percepções de adolescentes sobre sua sexualidade

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    Kelly Ribeiro de Freitas

    2010-01-01

    Full Text Available Es un estudio cualitativo de naturaleza descriptiva, con el objetivo de conocer las percepciones de los adolescentes sobre el desarrollo de su sexualidad. Se utilizó el enfoque del método creativo y sensible que presenta una alternativa a la investigación en enfermería a través de la dinámica de grupos de "creatividad y sensibilidad". Los participantes del estudio son 12 adolescentes de una escuela estatal de Porto Alegre. Para la recolección de los datos se hicieron cuatro talleres. El análisis siguió las etapas del método en el contexto de la pedagogía crítica de Paulo Freire. Tres temas emergieron del análisis: el adolescente: conflictos y dificultades de vida; la sexualidad para los adolescentes; y el acto sexual. Se considera importante hacer hincapié en que las percepciones de los adolescentes sobre su sexualidad surgieron en los debates y la alianza de conocimientos durante las reuniones, lo que contribuyó a la creación de un nuevo ambiente de diálogo en el contexto escolar que promovió y ayudó a la profundización del tema en un lenguaje accesible, en colaboración con los adolescentes.

  14. Efecto in vitro de aceites esenciales de tres especies de Lippia sobre Moniliophthora roreri (Cif. y Par. Evans et al., agente causante de la moniliasis del cacao (Theobroma cacao L.

    Directory of Open Access Journals (Sweden)

    Betty Stefany Lozada

    2012-04-01

    Full Text Available Se evaluó el efecto antifúngico in vitro de cinco aceites esenciales (AEs (AE1, AE2, AE3, AE4 y AE5 extraídos de Lippia origanoides, L. citriodora y L. alba sobre aislados de monilia (Moniliophthora roreri obtenidos de frutos de cacao infectados provenientes de San Vicente de Chucurí, Santander, Colombia. Las plantas de Lippia fueron colectadas en cinco localidades colombianas. Los aislados de monilia (M1, M2, M3, M4 y M5 fueron caracterizados por su morfología, germinación y crecimiento en medios de cultivo. La actividad antifúngica de diferentes concentraciones de los AEs fue evaluada contra el aislado M2 y la cepa de M. roreri (ATCC 64239, para determinar su efecto sobre la germinación y la inhibición del crecimiento micelial. Los AEs estudiados inhibieron 100% de la germinación y del crecimiento micelial cuando fueron utilizados en concentraciones de 800 - 1000 µg/ml. Concentraciones de 200 µg/ml también mostraron efecto sobre los aislamientos fúngicos, siendo los AEs obtenidos de L. origanoides (AE2 y AE3 los más activos. Estos estaban compuestos principalmente por timol, p-cimeno, g-terpineno, acetato de timilo, carvacrol, b-mirceno, trans-b-cariofileno. Diferencias significativas (P < 0.05 sobre la susceptibilidad se observaron entre las dos cepas fúngicas estudiadas, siendo en general más susceptible el aislado M2 que la cepa ATCC. Los AEs de L. origanoides son candidatos para ser usados como posibles biofungicidas en el control de la moniliasis. Son necesarios estudios futuros orientados a determinar la actividad in vivo antifúngica de estos AEs y sus principales componentes.

  15. Advecciones de polvo africano sobre la costa central venezolana y sus efectos sobre el desarrollo de la nubosidad

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    Estatio José Gutiérrez Quevedo

    2006-01-01

    Full Text Available Empleando el índice de aerosol, determinado a través de las mediciones del sensor TOMS, se ha realizado un análisis del comportamiento de las magnitudes del parámetro sobre la costa central venezolana en base al período 19972005; los resultados señalaron que se presentaron los máximos valores del índice en los meses de Julio y Agosto correspondientes a la temporada de lluvias. Para este período las masas de aire cargadas de partículas de polvo llegan al Caribe provenientes del desierto del Sahara, como lo demuestra el mapa con la distribución espacial de la mediana del índice para el mes de julio, por el contrarío existe una disminución sustancial en la cantidad de partículas dispersas sobre la troposfera venezolana en la temporada seca en donde las nubes de polvo se desplazan generalmente desde el Sahel. Los productos atmosféricos del sensor MODIS han sido utilizados para determinar la relación entre la concentración de aerosoles y el comportamiento de la nubosidad, presentando ésta una disminución en su desarrollo en presencia de valores altos del índice de aerosol principalmente en los meses de abril y mayo.

  16. Considerações sobre cuidado paliativo e trabalho hospitalar: uma abordagem plural sobre o processo de trabalho de enfermagem

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    Miguel de Simoni

    2003-01-01

    Full Text Available O objetivo deste artigo é apresentar o esforço de síntese dos autores sobre material de pesquisa em cuidados paliativos e bibliografia estudada. Inicialmente, apresentamos algumas considerações sobre cuidado paliativo em dois países estruturalmente distintos, Brasil e França. A discussão está centrada nas experiências de pesquisa dos autores em um serviço de AIDS no Brasil e em um serviço de Medicina Interna na França, que adotava a lógica dos cuidados paliativos e abrigava predominantemente pacientes com AIDS e câncer. Abordamos, em seguida, aspectos referidos à dor e à morte, considerando conceitos da Bioética e a dimensão relacional do cuidado em saúde. Os conceitos assinalados são os de justiça, autonomia, beneficência e não-maleficência. Concluímos, apresentando algumas possíveis contribuições da Ergonomia e da Psicodinâmica do Trabalho na área de Cuidados Paliativos, considerando especialmente a dimensão psicológica deste debate.

  17. Eflorescencias y costras sobre areniscas de Villamayor. Ensayos de laboratorio

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    Madruga, F.

    1994-06-01

    Full Text Available Accelerated tests carried out in the laboratory allow us to study the crystalline material settled over the surface of the sandstones when in contact with watery solutions of different compositions. Sandstone specimens of three different textures were placed on trays containing watery solutions, putting one surface in contact with the liquid. In order to accelarate the capillary absorption, a flow of air was established over the opposite surfaces. The humidity and dryness cycles were repeated 45 times. The crystallized salts were identified by X-ray diffraction, SEM and chemical microanalysis by X-rays dispersive energy. The following results were obtained: gypsum, hexahydrite, picromerite, natrone, arcanite in saline solutions; trone, aftitalite, and presence of gypsy m in cement solutions; gypsum and syngenite in the guano solution test. These salts are analogous to those found in the superficially damaged stones of the Cathedral of Salamanca.

    Ensayos acelerados realizados en el laboratorio, permiten estudiar el material cristalino depositado sobre la superficie de areniscas cuando están en contacto con disoluciones acuosas de diferente composición. Probetas de areniscas de tres texturas diferentes se colocan sobre bandejas que contienen las disoluciones acuosas, de tal forma que una de las superficies esté en contacto con el líquido. Sobre las superficies opuestas se establece una corriente de aire que acelere la absorción capilar del líquido. Ciclos de humedad y secado se repiten 45 veces. Las sales cristalizadas se identifican por difracción de rayos-X, SEM y microanálisis químico por energía dispersiva de rayos-X. Los resultados son los siguientes; yeso, hexahidrita, picromerita, natrón y arcanita cuando se trata de disoluciones salinas; trona, aftitalita y presencia de yeso cuando la disolución es de cemento; yeso y syngenita en el ensayo con disolución de guano. Estas sales son análogas a las encontradas en las

  18. Anotaciones sobre patología del esófago

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    Ibañez Castro, H.

    2010-01-01

    Actualidad sobre el tratamiento de la patología de esta parte del tubo digestivo. El artículo quiere llamar la atención sobre puntos poco frecuentados en general: Ampula frénica - Hernia diafragmática - Estemosis extrínsecas - Megaesófago - Causas locales - Causas extrínsecas

  19. Estudio muestra importancia de conversaciones tempranas sobre el cuidado en etapa final de la vida

    Science.gov (United States)

    Artículo sobre la importancia de hablar en forma temprana sobre el cuidado paliativo para asegurar que la atención prestada en la etapa final de la vida sea más acorde con las preferencias de los pacientes.

  20. Efecto in vitro de aceites esenciales de tres especies de Lippia sobre Moniliophthora roreri (Cif. y Par.) Evans et al., agente causante de la moniliasis del cacao (Theobroma cacao L.) In vitro effect of essential oils of three Lippia species on Moniliophthora roreri (Cif. and Par.) Evans et al., causative agent of moniliasis of cocoa (Theobroma cacao L.)

    OpenAIRE

    Betty Stefany Lozada; Laura Viviana Herrera; Janeth Aidé Perea; Elena Stashenko; Patricia Escobar

    2012-01-01

    Se evaluó el efecto antifúngico in vitro de cinco aceites esenciales (AEs) (AE1, AE2, AE3, AE4 y AE5) extraídos de Lippia origanoides, L. citriodora y L. alba sobre aislados de monilia (Moniliophthora roreri) obtenidos de frutos de cacao infectados provenientes de San Vicente de Chucurí, Santander, Colombia. Las plantas de Lippia fueron colectadas en cinco localidades colombianas. Los aislados de monilia (M1, M2, M3, M4 y M5) fueron caracterizados por su morfología, germinación y crecimiento ...

  1. Barbon versus Locke sobre o valor da moeda

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    Mauricio C. Coutinho

    2011-12-01

    Full Text Available O artigo discute as posições contrastantes de Nicholas Barbon e John Locke no debate monetário inglês sobre a "valorização do dinheiro" dos anos 1690. Embora referidos às condições do sistema monetário inglês da época, os temas e argumentos do debate foram fundamentais na formação da teoria monetária e da teoria econômica, entre o final do século XVII e o século XVIII. O artigo acompanha a crítica de Barbon a Locke, e procura efetuar um sumário da teoria monetária de Locke, cuja importância no debate econômico se estendeu por 150 anos.

  2. Revestimientos asfálticos sobre bases continuas

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    Eberle, Karl

    1963-10-01

    Full Text Available In the course of a meeting connected with research on road pavements, held at Konstance, in Germany, Dr. Eberle submitted for discussion and study two new methods for the construction of modern pavements. In general outline, the first of these methods consists in placing a layer of gravel, of about 18 cms depth, on top of the foundation base, after suitably treating the latter to protect it against frost. An asphaltic layer of much smaller depth is then placed on the gravel layer, which constitutes a flexible base. The asphaltic layer is the actual traffic pavement. The second method is similar to the first as regards the grading, box and foundation. The only difference is that cement mortar is applied to the gravel base, into the hollow spaces of which the mortar is made to penetrate. In both methods the top pavement is consolidated mechanically by means of suitable auxiliary equipment. The choice of one or other of the previous two methods depends on the results obtained from a general study of the location and quality of the available crushed stone, and on the facility to transport these materials to the prepared graded subbases. The author claims that the rational use of these methods gives good results, both technically and economically.Con motivo de celebrarse una reunión encargada de la investigación I sobre firmes para carreteras, verificada en Konstanz, Alemania, el autor expuso para su estudio y consideración dos nuevos métodos constructivos para afirmados modernos. El primero de estos métodos consiste, a grandes rasgos, en colocar una capa, de grava, de unos 18 cm de espesor, sobre la superficie de la base de cimiento, convenientemente tratada, para protegerla contra las heladas. Sobre esta capa, que constituye un firme flexible, se coloca otra asfáltica de mucho menor espesor, que sirve de rodadura. El segundo método es similar al anterior en lo que se refiere a la explanación, caja y cimiento; la única diferencia estriba en

  3. Algunas consideraciones teóricas sobre el liderazgo transformacional

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    Otilia Bracho Parra

    2013-05-01

    Full Text Available El artículo tuvo como objetivo, realizar algunas consideraciones teóricas sobre el liderazgo transformacional, tomando como referencia los planteamientos de Bass y Avolio (2006, Velásquez (2006, Lerma (2007, Leithwood, Mascall y Strauss (2009, entre otros. El proceso metodológico implico revisión bibliográfica, a través de la hermenéutica. Concluyendo que el liderazgo transformacional implica convertir a los colaboradores en personas creativas, motivadas al logro, comprometidas e identificadas con la organización, además de inspirar en sus seguidores la participación, pensar en colectivo, esforzándose en alcanzar metas significativas, en pro de la misión y visión de la empresa.

  4. Sobre el allanamiento al interior de los grupos societarios

    OpenAIRE

    Cubillos Garzón, Camilo

    2014-01-01

    Comprender cómo una teoría jurídica societaria afecta el desarrollo de un fenómeno económico es una tarea compleja, pero si además se considera que esta anomalía se inmiscuye en otro suceso mercantil, como es el de una situación patrimonial de hecho, el asunto aparece aún más confuso; comenzando de esta manera, y a partir de tales supuestos, es un deber concretar el marco sobre el cual girará esta investigación. Los partícipes de una economía perciben separadamente las políticas de crecimi...

  5. Notas sobre el contenido del Principio de la democracia

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    Pablo Marshall Barberan

    2011-07-01

    Full Text Available El presente trabajo busca exponer aspectos sustantivos del principio de la democracia.Para ello se vale de las importantes investigaciones que, inspiradoen la metodología de Carl Schmitt, E.W. Böckenförde ha realizado sobre elcontenido y alcance de la cláusula democrática en el derecho constitucionalpositivo. Para ello se realiza una pequeña explicación del rol que cabe ala democracia en la teoría de las formas de gobierno para después tratar elfundamento, rol y aplicación que tiene el principio de la democracia comoprincipio constitucional reconocido en el ordenamiento jurídico. Se fi nalizacon una breve aplicación de la teoría al caso del sistema jurídico chileno.

  6. Apuntes sobre historia empresarial: Relatos de algunas experiencias

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    Elber Berdugo Cotera

    2003-10-01

    Full Text Available El presente articulo tiene como objetivo mostrar la importancia de la Historia Empresarial y la constitución de una línea de investigación para el entendimiento de la historia del país y la comprensión de las principales características de nuestros empresarios tanto en el ámbito regional como en el nacional. Se trata igualmente, de dar cuenta de los aspectos teóricos y metodológicos utilizados en la investigación sobre el estudio de caso de Servientrega y sus gestores, lo mismo que de los principales hallazgos encontrados en ella. Por último, señalar cómo ésta clase de experiencias pueden resultar enriquecedoras para aquellas personas que ejercen una función educativa empresarial o pretenden asumir como proyecto personal y familiar de vida ser empresarios.

  7. Carlos Cruz : um olhar sobre o escândalo

    OpenAIRE

    Diniz, Mafalda

    2012-01-01

    O trabalho apresentado sob o título Carlos Cruz: um olhar sobre o escândalo, aborda o caso Carlos Cruz. Este insere-se no processo Casa Pia e é visto como um escândalo mediático. Atualmente, a palavra “escândalo” aparece com alguma frequência nos mass media. Esta palavra prende-se com a transgressão dos códigos morais que provocam a desaprovação dos outros. Algumas transgressões são pequenas demais para serem consideradas escândalo, enquanto outras podem ser demasiado sérias. O escândal...

  8. Los procesos ante los juzgados de violencia sobre la mujer

    OpenAIRE

    Laguna Pontanilla, Gonzalo

    2015-01-01

    La entrada en vigor de la "Ley Organica 1/2004, de 28 de diciembre, de Medidas de Protección integral contra la Violencia de Género, generó desde su origen graves críticas, a nivel ideológico, dogmático y doctrinal, y una compleja y heterogénea problemática en la práctica judicial que cristalizó en diversas cuestiones interpretativas que plantea la aplicación práctica de la Ley Integral a diario en los proxcesos seguidos ante los juzgados de Violencia sobre la Mujer. La tesis aborda la neces...

  9. Influencia del CO2 sobre un cemento portland anhidro

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    Gaspar-Tebar, Demetrio

    1976-03-01

    Full Text Available Not availableEn el lETcc se han desarrollado diversos trabajos para determinar la influencia que el aire húmedo ejerce sobre las propiedades de distintos conglomerantes hidráulicos industriales con el fin de fijar un límite al tiempo durante el cual un conglomerante puede conservarse sin que pierda su valor hidráulico; estos trabajos han dedicado la mayor atención a la evolución de las resistencias mecánicas, así como a la finura, trabajos que se completaron, posteriormente, con la aplicación de la espectrometría IR (1, (2.

  10. INFORME SOBRE DESLAZAMIENTO FORZADO Y PROBLEMÁTICA AGRARIA

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    Nicolás Castrillón

    2008-12-01

    Full Text Available El presente articulo presenta resultados de investigación sobre las causas del desplazamiento forzado y la problemática agraria en Colombia. Para entender esta problemática es necesario el análisis de las políticas macroeconómicas dictaminadas desde los principales organismos financieros y las multinacionales con mayor acumulación de capital en el mundo (El BM, el FMI, El BID, la OMC, entre otros, quienes influyen de manera determinante en las economías periféricas y en los sistemas políticos que se han de configurar en los países subdesarrollados para garantizar el buen desarrollo del modelo neoliberal y por ende, la acumulación acelerada del capital.

  11. Informe sobre el XIII congreso internacional de Ahila

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    Fernando Mayorga García

    2010-08-01

    Full Text Available Informe sobre el XIII congreso internacional de Ahila , Azores,  Entre el 3 y el 6 de septiembre de 2002, en la Universidad de las Azores (Ponta Delgada, sesionó el XIII Congreso Internacional de la Asociación de Historiadores Latinoamericanistas Europeos (AHILA convocado bajo el lema "El Atlántico como eslabón de unión de pueblos: sociedades, políticas, economías y culturas". La conferencia inaugural tuvo lugar en el Complejo Científico de la Universidade dos Acores y estuvo a cargo del doctor Avelino de Freitas Meneses, quien se refirió al tema "Os Acores no centro do mundo: um propósito de reflexao histórica".

  12. Desenvolvimento da Tanatologia: estudos sobre a morte e o morrer

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    Maria Julia Kovács

    2008-12-01

    Full Text Available Este artigo discute os principais temas e pesquisas na área da Tanatologia, estudos sobre a morte e o morrer. São apresentados os autores pioneiros que escreveram as primeiras obras de sistematização da Tanatologia entre os quais: Herman Feifel, Robert Kastenbaum e Elizabeth Kübler-Ross, e os principais temas de estudo: luto, violência e guerra, a morte e a TV, cuidados a pacientes gravemente enfermos, além da formação de profissionais da área de saúde e educação para lidar com pessoas vivendo situações de perdas e morte. São feitas propostas de estudos para o futuro desenvolvimento da Tanatologia em nosso país.

  13. UNA PERSPECTIVA NEUROCIENTÍFICA SOBRE LA HISTERIA

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    Lucía Amoruso

    2010-01-01

    Full Text Available En la última década, el desarrollo y la puesta en marcha delas modernas técnicas de neuroimagen en el campo de laneurociencia cognitiva han proporcionado una nueva vía deacercamiento al estudio experimental de algunos trastornosmentales. Dentro de esta perspectiva, denominada por algunosautores “neuropsiquiatría cognitiva”, la histeria (o trastornode conversión, de acuerdo con la clasificación psiquiátricaactual ha cobrado un amplio protagonismo. De acuerdo conlo anterior, el objetivo del presente trabajo consiste en introducirestudios pioneros basados en una perspectiva neurocientíficade la histeria. Conviene destacar que, si bien estosaportan evidencia significativa sobre algunas de las áreascerebrales y las disfunciones cognitivas comprometidas enel mencionado trastorno, los resultados obtenidos a la fechadistan aún de ser concluyentes.

  14. Sobre las bases prejurídicas del derecho ambiental

    OpenAIRE

    Souvirón Morenilla, José María

    2015-01-01

    La preocupación por el ambiente, en sí mismo considerado y en su relación con el ser humano, son un fenómeno característico de nuestro tiempo. Sobre este soporte científico y la paralela reflexión ética, el ambiente se ha incorporado de modo progresivo también al campo del Derecho y la protección del ambiente se ha convertido en un título legitimador de la intervención de los poderes públicos decididamente expansivo.Dado el riesgo global que el problema ambiental hoy suscita, n...

  15. Reflexiones sobre el futuro del servicio social universitario

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    Concepción Cano Castellanos

    2004-01-01

    Full Text Available El presente artículo pretende compartir algunas reflexiones sobre el futuro del servicio social universitario, enriqueciendo el concepto de servicio con el de educación humanista ya que ésta es la base que impulsa la realización de proyectos comunes a futuro. Dichas reflexiones parten de la experiencia vivida en la Universidad Iberoamericana a ese respecto. Dentro de los retos para mejorar el servicio social en el futuro se plantea la opción de integrarlo al currículum universitario como un proceso de reconstrucción práctica, y una serie estructurada de conocimientos y experiencias de aprendizaje que se traduzcan en formas de pensar y actuar frente a los problemas de la realidad.

  16. Puente Kohlbrand Sobre el Elba Hamburgo -Alemania Federal

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    Schwab, Rudolf

    1976-02-01

    Full Text Available The suspension bridge, in the port of Hamburg, is one of the most important engineering works in northern Germany. The work is divided into three sectors: 1 The eastern accommodation ramp, 2,410 m long. 2 The bridge across the river bed, 520 m long. 3 The western accommodation ramp, -,050 meters. The bridge is 17.60 m wide and has four traffic lanes. Sectors 1 and 3 were solved by means of prestressed concrete superstructures, with one or two cell box girders. Sector 2 has a 325 m span between the two piers and a 54 m high and 150 m ship passage. The central piers that rise 130 m above the ground consist of a base of reinforced concrete and a 98 m high metallic part, formed by a box of bolted and subsequently welded beams. In the upper part of this last part are the connections for the suspension cables for the overhanging part of the bridge. The construction works were carried out beginning with sectors 1 and 3 on both sides of the river simultaneously. Once these were completed and the piers were raised, the work.El puente elevado de Kohlbrand, en el puerto de Hamburgo, es una de las obras de ingeniería más importantes de la parte norte de Alemania. La obra se divide en tres sectores: 1° La rampa este de acceso, de 2.410 m. 2° El puente sobre el cauce del río, de 520 m. 3° La rampa oeste de acceso, de 1.050 m. El puente tiene 17,60 m de anchura y cuatro carriles. Los sectores 1.» y 3.° se resolvieron mediante superestructuras de hormigón pretensado, con vigas cajón de una o dos células. El sector 2.° posee una luz de 325 m entre las dos pilas principales, y una altura útil de paso sobre el nivel del agua de 54 m en un ancho de 150 m. Las pilas centrales, de 130 m de altura sobre la cota del terreno, se hallan constituidas por una base de hormigón armado y una parte metálica de 98 m de altura, formada por un cajón de vigas atornilladas y posteriormente soldadas. En la parte superior de esta última se

  17. Mecanismos de control sobre la seguridad privada en el Brasil

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    Carolina de MATTOS RICARDO

    2009-01-01

    Full Text Available RESUMEN: El presente artículo sistematiza los mecanismos de control sobre la seguridad privada en el Brasil, ya sean éstos legales, institucionales o externos. La sistematización permite evaluar la organización de la estructura de reglamentación y fiscalización, así como la regularización de la prestación de estos servicios. Al final del artículo se dan algunas sugerencias para el perfeccionamiento de ese sistema.ABSTRACT: This article systematizes the control mechanisms on the private security in Brazil – the legal as well as the institutional and the external ones. That systematization enables to evaluate the organization of the structure of regulation and fiscalization, as well as the regularization of the provision of these services. At the end of the paper, some suggestions are proposed for the improvement of that system.

  18. Sobre la complejidad del Estado y las contrataciones administrativas

    Directory of Open Access Journals (Sweden)

    Armando Rodriguez García

    2011-12-01

    Full Text Available El tema de los contratos que celebra el Estado ha significado un tema de interés constante para el Derecho administrativo, debido a las particularidades que adoptan las figuras contractuales aplicadas en el sector público en el orden científico. Adicionalmente ese interés se ha incrementado con la ampliación del empleo de los contratos -con ocasión de los cambios operados por la globalización-. El enfoque que se ofrece a continuación apunta a la consideración de la complejidad presente en la acción pública, para así comprender mejor el entorno de los contratos públicos y su alcance, y obtener una clara perspectiva sobre lo que aporta el Derecho administrativo global.

  19. Personajes: notas sobre Deleuze y la novela modernista

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    Juan Carlos Gorlier

    2012-12-01

    Full Text Available Las contribuciones de Deleuze revelan nuevas dimensiones en la literatura modernista. Para muchos escritores modernistas, lo que la conciencia puede captar es menos relevante que lo que afecta al cuerpo; esta convicción se plasma en la aparición de personajes difíciles de clasificar. La primera sección del ensayo explora la relación entre acontecimiento y personaje; la segunda indaga las reflexiones de Nietzsche sobre Zaratustra; la tercera está dedicada a la noción de personaje original en Melville; la cuarta presenta la idea de los personajes como fuerzas impersonales en Lawrence; y la última la concepción del personaje ausente en Woolf.

  20. Notas sobre o autotelismo discursivo em ciências humanas

    Directory of Open Access Journals (Sweden)

    Paulo Eduardo Lopes

    1994-12-01

    Full Text Available O Ateliê de Semiótica Discursiva, coordenado por Denis Bertrand, propôs focalizar, no ano letivo 1991-1992, a " Estética do Discurso Erudito", no quadro da temática "Estética da Ética" do Seminário de Semântica Geral, de A.J . Greimas, na Escola de Altos Estudos em Ciências Sociais de Paris (E. H. E. S. S.. Bertrand distribuiu cópias de trechos de textos célebres em ciências humanas (Lévi-Strauss, Deleuze e Guattari, Greimas, Barthes, Foucault e outros, sobre os quais os participantes deveriam realizar análises que tomassem como modelo, por exemplo, aquelas praticadas por Greimas e Landowski em lntroduction à L 'Analyse du Discours en Sciences Sociales ( 1979.

  1. Sobre Análise do Relato Verbal

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    Tunes Elizabeth

    1998-01-01

    Full Text Available Neste artigo caracterizamos descritivamente aspectos básicos de um trabalho coordenado pela Professora Carolina Bori, junto ao Ciclo Básico da Universidade Federal de São Carlos, em 1977, trabalho este que desencadeou duas vertentes de pesquisa no Brasil: uma no âmbito do ensino de Química e a outra no âmbito da pesquisa com relatos verbais em Psicologia. Descrevemos, em seguida, as principais características de cada uma dessas vertentes, em termos das questões que as originaram e dos primeiros trabalhos que daí resultaram. Finalmente, contextualizamos a contribuição da abordagem ao relato verbal assim construída para a pesquisa em psicologia, especialmente à luz de colocações de Vygotsky sobre o papel dos relatos verbais na pesquisa experimental.

  2. Teorías sobre cobertura con contratos de futuro

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    Aragó Mananza Vicent

    2009-10-01

    Full Text Available En este trabajo se presenta una revisión de las principales teorías sobre cobertura con contratos de futuro y de los distintos métodos de estimación utilizados para determinar el ratio de cobertura óptimo. La aproximación a la cobertura más utilizada en la literatura especializada es la basada en el modelo de la teoría de carteras. No obstante, debido a sus hipótesis relacionadas con la función de utilidad del inversor y con las propiedades de la función de distribución de los rendimientos, XI han surgido nuevas propuestas (por ejemplo, las construidas a partir del coeficiente de Gini y el concepto de Lower Partial Moments, que intentan reducir dichas restricciones.

  3. Resúmenes de los trabajos sobre enfermedades cerebrovasculares

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    Congreso Nacional de Neurología

    2010-03-01

    Full Text Available La enfermedad cererebrovascular constituye un serio problema sociosanitario, actualmente se considera una de las principales causas de muerte en la población adulta, con tendencia creciente en su incidencia y prevalencia en la población cubana de dichas edades. Teniendo en cuenta la importancia de las investigaciones científicas para cambiar ese curso, en el salón sobre estas enfermedades que sesionó en el marco del Congreso Nacional de Neurología, se presentaron un total de 33 trabajos científicos que abordaron de una forma u otra aspectos relacionados con estos temas. A continuación se presentan los resúmenes de los artículos presentados en el orden de presentación. También se puede encontrar en ellos las direcciones electrónicas de los responsables de cada resumen.

  4. Estudos sobre a paz e cultura da paz

    OpenAIRE

    Pureza, José Manuel

    2000-01-01

    Segundo o autor, a cultura da paz implica uma mudança quer na forma como a “alta cultura” lida com a realidade quer no tipo de abordagem que o senso comum faz às relações sociais, sendo que a ruptura com a ideologia conservadora, ou seja, com o senso comum realista só é possível graças a estas alterações. O autor realça tanto a importância que os estudos sobre a paz têm para o surgimento de um conceito amplo de paz, desenvolvido por Johan Galtung, como o facto destes esta...

  5. A first-principles density functional theory study of the electronic structural and thermodynamic properties of M2ZrO3 and M2CO3 (M=Na, K) and their capabilities for CO2 capture

    Energy Technology Data Exchange (ETDEWEB)

    Yuhua Duan

    2012-01-01

    Alkali metal zirconates could be used as solid sorbents for CO{sub 2} capture. The structural, electronic, and phonon properties of Na{sub 2}ZrO{sub 3}, K{sub 2}ZrO{sub 3}, Na{sub 2}CO{sub 3}, and K{sub 2}CO{sub 3} are investigated by combining the density functional theory with lattice phonon dynamics. The thermodynamics of CO{sub 2} absorption/desorption reactions of these two zirconates are analyzed. The calculated results show that their optimized structures are in a good agreement with experimental measurements. The calculated band gaps are 4.339 eV (indirect), 3.641 eV (direct), 3.935 eV (indirect), and 3.697 eV (direct) for Na{sub 2}ZrO{sub 3}, K{sub 2}ZrO{sub 3}, Na{sub 2}CO{sub 3}, and K{sub 2}CO{sub 3}, respectively.The calculated phonon dispersions and phonon density of states for M{sub 2}ZrO{sub 3} and M{sub 2}CO{sub 3} (M = K, Na, Li) revealed that from K to Na to Li, their frequency peaks are shifted to high frequencies due to the molecular weight decreased from K to Li. From the calculated reaction heats and relationships of free energy change versus temperatures and CO{sub 2} pressures of the M{sub 2}ZrO{sub 3} (M = K, Na, Li) reacting with CO{sub 2}, we found that the performance of Na{sub 2}ZrO{sub 3} capturing CO{sub 2} is similar to that of Li{sub 2}ZrO{sub 3} and is better than that of K{sub 2}ZrO{sub 3}. Therefore, Na{sub 2}ZrO{sub 3} and Li{sub 2}ZrO{sub 3} are good candidates of high temperature CO{sub 2} sorbents and could be used for post combustion CO{sub 2} capture technologies.

  6. Debates sobre el exilio en la revista Controversia

    Directory of Open Access Journals (Sweden)

    Juan Pablo Gauna

    2016-03-01

    Full Text Available El artículo que presentamos retoma cuestiones trabajadas en el Seminario Los exilios políticos masivos contemporáneos en España y Cono Sur. Una aproximación desde los estudios comparados y transnacionales de la Universidad Nacional de La Plata. En el mismo reflexionamos sobre las polémicas del exilio impulsadas desde la revista Controversia para el examen de la realidad argentina (1979-1981. El recorrido que proponemos incluye la ubicación de Controversia en un contexto de experiencias exilares parecidas, y el repaso de los temas centrales que intersectan la cuestión del exilio –la derrota, derechos humanos, los intelectuales y la política, entre otros. Como hilos conductores del análisis confrontaremos la categoría de exilio propuesta por Luis Roniger y Mario Sznajder con los ensayos de caracterización del exiliado que hacen los redactores de la revista; al mismo tiempo se pondrá de manifiesto las memorias en pugna sobre el período de la última dictadura militar argentina. La apuesta de este trabajo apunta a reponer el derrotero de la crítica a los proyectos políticos que terminaron en el exilio, con las modulaciones específicas propiciadas desde la revista que analizamos; y abrir interrogantes que entren en diálogo las propias preguntas de los editores de la publicación.

  7. Cine comercial y conocimiento sobre el proceso de morir

    Directory of Open Access Journals (Sweden)

    María Campo-Redondo

    2009-05-01

    Full Text Available El cine como recurso tecnológico para generar conocimientos ha empezado a dar sus frutos. En este artículose presenta los resultados de la inserción del cine en la generación de conocimientos bajo dos vertientes: una teórica,discutiendo la intersección entre la era de la tecnología digital y el modo de crear conocimiento propio de esta era, yotra empírica, describiendo una propuesta de utilización didáctica del “cine comercial” con el fin de analizar el significadode la muerte. Así, el artículo se divide en cinco sub-partes. En primer lugar, se contextualiza la era de la tecnologíadigital en la creación de conocimiento. En segundo lugar, se resalta las ventajas de utilizar el cine en la transmisión deconocimiento, en especial aquel que es difícil de adquirir por la vía experiencial. En tercer lugar, se describe la metodologíautilizada en la aplicación de una propuesta didáctica llevada a cabo con estudiantes de una cátedra de Psicologíadel Desarrollo, en la que la película “Antes de Partir” fue el estímulo sobre el cual se organizó la discusión relacionadacon el fin del ciclo la vida de los seres humanos. En cuarto lugar, se resume los hallazgos más importantes sobre estaexperiencia de investigación, al combinar el cine con aspectos teóricos relacionados con la conceptualización de lamuerte. Por último, se destaca las virtudes de la metodología empleada.

  8. GPLAD: PROGRAMACIÓN ESTRUCTURADA SOBRE DISPOSITIVOS ANDROID

    Directory of Open Access Journals (Sweden)

    LUISA FERNANDA HERNÁNDEZ RAMÍREZ

    2012-12-01

    Full Text Available La programación por medio de bloqueses un enfoque visual que permite a las personas jóvenesadquirir interés en el desarrollo de software.Así lo han demostrado herramientas para computadorescomo Scratch, StarLogo y Alice. Hoy en díahay estudiantes e ingenieros programadores quedesean implementar soluciones más estructuradas yhay pocas herramientas que, a través de programacióngráfica ofrezcan la posibilidad de solucionar problemasque se manejen en primeros semestres universitarios.Por otro lado, los dispositivos móviles, enespecial los que poseen sistema operativo Android,han tenido acogida en los últimos años, además, sonutilizados para resolver problemas en tiempo real.El objetivo de este trabajo fue demostrar la utilidadde una aplicación que soporta la programación estructuradapor medio de bloques sobre dispositivosAndroid, que facilita la creación y ejecución de códigoen el lenguaje Java sobre un servidor remoto. Serealizó un análisis para determinar el ambiente deprogramación, la creación de bloques con su representaciónintermedia y las validaciones para la generaciónde código, además, se realizaron pruebas através de la formulación de problemas matemáticosque se enseñan durante los primeros cursos de Ingenieríade sistemas en la Fundación UniversitariaSan Martín. Finalmente, se obtuvo el código Javade la solución a cada problema planteado dentro deGplad

  9. Estudio sobre patentes y dominio público

    Directory of Open Access Journals (Sweden)

    Ernesto Rengifo García

    2011-11-01

    Full Text Available Este artículo analiza el impacto del sistema de patentes y el dominio público en el desarrollo de la ciencia, la innovación y la tecnología en Colombia. A partir de la estructuración de una política pública sobre el tema, el gobierno colombiano busca garantizar una protección efectiva para la actividad creadora y fomentar el acceso y la utilización de los avances técnicos encontrados en documentos de patente de dominio público. Los principales objetivos de esta iniciativa son fomentar la creación y la innovación mediante el uso del sistema de propiedad intelectual y su promoción como mecanismo para el desarrollo de los negocios, de la empresa y generación de empleo en el país. En virtud de dichos esfuerzos, el Estado, a través de las entidades delegadas del gobierno para tal fin, ha avanzado en la gestión y promoción de la información de patentes de dominio público, por medio de la capacitación sobre la utilización eficiente, la investigación y el uso de bancos de patentes. Si bien esta tarea ha generado avances importantes, ha sido insuficiente para consolidar la correcta utilización de las herramientas tecnológicas y es necesario reforzar las estrategias y aunar esfuerzos para que el uso de esta información pueda reflejarse en la creación de nuevas tecnologías o en la mejora de las existentes.

  10. A gênese do imposto sobre o valor agregado

    Directory of Open Access Journals (Sweden)

    Ubaldo César Balthazar

    2008-06-01

    Full Text Available Este artigo tem como objetivo analisara história do princípio das deduções, ínsito aoImposto sobre o Valor Agregado, a partir de umaanálise de textos das doutrinas francesa e belga,principalmente. Procura demonstrar que, ao contráriodo que pretendem autores franceses, o citadoprincípio não foi pensado originalmente naFrança, mas foi antes produto de um processoevolutivo registrado em vários ordenamentos positivos.Em um segundo momento é estudada ainstituição do IVA francês, verificando-se os avançose recuos, as dificuldades encontradas no longoprocesso de consolidação do imposto naquele país.Com isso pretende-se oferecer uma reflexão à doutrinabrasileira, no momento em que se discute ainstituição de um imposto sobre o valor agregadono direito positivo pátrio.The objective of the article is toanalyze the history of the principles ofdeduction, in accordance with the ‘Tax on AddedValue’, and primarily from an analysis of textsof the French and Belgian doctrine. The articlewill demonstrate that, in contrast of intendFrench authors, cited principle was not thoughtoriginally in France, but rather a registeredevolutionary process in some positive orders.Secondly, the French institution IVA will bestudied, assessing its pros and cons as well aslooking at the difficulties found in the longprocess of tax consolidation in that country. Thisis intended to offer a reflection of thecorresponding Brazilian doctrine, when it isbeing discussed the imposition of a ‘Tax onAdded Value’ in the native positive law.Keys-words: Tax, Principle of deduction, TaxHistory, Buttoir rule, Added value.

  11. Paso elevado sobre el ferrocarril, en Cannes Francia

    Directory of Open Access Journals (Sweden)

    Idelberger, Klaus

    1979-12-01

    Full Text Available This article describes the construction in Cannes of the third section of an overpass bridging a number of railway tracks and platforms, achieving the supression of many curves in the coastal highway and this without Interfering with city traffic. For this third section the construction method chosen was a metal structure, despite the fact that the two previous sections were built in concrete. This overpass section has 15 spans, 14 of them are solved with a grid of welded beams supporting reinforced concrete slabs while the remaining span is a grid of laminated beams on concrete. The total amount of steel used was 3360 Tm, aside from the foundations and decking reinforcements.

    Se describe en este artículo la construcción, en Cannes, de la tercera fase de un paso elevado realizado sobre andenes y vías de ferrocarril, con el que se consigue eliminar una serle de curvas de la carretera costera y, además, no interferir el tráfico en la ciudad. Para este tercer tramo se eligió la construcción a base de estructura metálica, a pesar de que los dos tramos anteriores eran de hormigón. Se construyeron 15 vanos, de los cuales 14 de ellos llevan un emparrillado de vigas soldadas con losas de hormigón armado y el otro es un emparrillado de vigas laminadas sobre hormigón. El total de acero utilizado fue de 3.360 t sin contar las armaduras de los cimientos y de los tableros.

  12. Sobre la edificación en arcillas expansivas

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    Llorca Aquesolo, J.

    1980-06-01

    Full Text Available The different problems that building on expansive clay presents are studied in this article and which do not have as complete and precise an answer as builders would need today. The lack of theoretical methods that would allow us to have feasible results about the possible danger of an expansive soil, and the fact that with land studies using laboratory tests — especially when these are made with inalterable samples — certain important results are obtained, but they are incomplete, and bring us to the conclusion that the analysis of local building experience and of the damages and deformations of the existing works, and also field measurements constitute the best information over the possibility and way of building on this kind of soil.

    En este artículo se estudian los diferentes problemas que plantea la edificación en arcillas expansivas, los cuales, hoy en día, no tienen una respuesta todo lo completa y precisa que necesitarían los constructores. La falta de métodos teóricos que nos permitan obtener resultados fiables sobre la posible peligrosidad de un suelo expansivo y el hecho de que, con el estudio del terreno mediante ensayos de laboratorio —especialmente cuando éstos se hacen con muestras inalteradas— se consiguen ciertos resultados importantes pero incompletos, nos llevan a la conclusión de que el análisis de la experiencia local de edificación y de los daños y deformaciones de las obras existentes, así como las mediciones de campo, constituyen la mejor información sobre la posibilidad y el modo de construir en este tipo de suelos.

  13. Reflexiones etnográficas sobre el ocio infantil

    Directory of Open Access Journals (Sweden)

    Begoña Leyra Fatou

    2014-06-01

    Full Text Available El presente artículo revisa y amplía parte de los resultados de un estudio realizado sobre el ocio infantil en la Comunidad de Madrid (España (Gaitán, Domínguez, Bárcenas y Leyra, 2011, tratando de analizar el concepto de ocio, como proceso educativo, que de manera transversal enlaza diferentes elementos de la vida cotidiana de niños y niñas. Asimismo, a través de estas páginas se examinarán los diferentes discursos, comportamientos y percepciones que tienen respecto al ocio tanto los niños y niñas como las personas adultas que participaron en la investigación. Se tratará de hacer un recorrido por la propia concepción del ocio infantil así como del tiempo libre, y de los usos y prácticas diferenciadas en distintos grupos de niños y niñas, analizando cómo el ocio forma parte de la educación formal y no formal, llevando consigo elementos transversales de género y edad. Para este estudio se contó con un “grupo junior” de investigación, compuesto por niños y niñas que realizaron reflexiones y aportaciones tanto a lo largo del proceso etnográfico como sobre los resultados obtenidos, fortaleciendo el propio enfoque de “Protagonismo Infantil” y de “Co-investigación de niños y niñas”.

  14. Constraints on the Distance Moduli, Helium and Metal Abundances, and Ages of Globular Clusters from their RR Lyrae and Non-Variable Horizontal-Branch Stars. I. M3, M15, and M92

    CERN Document Server

    VandenBerg, Don A; Catelan, Marcio

    2016-01-01

    Up-to-date isochrones, zero-age horizontal branch (ZAHB) loci, and evolutionary tracks for core He-burning stars are applied to the color-magnitude diagrams (CMDs) of M3, M15, and M92, focusing in particular on their RR Lyrae populations. Periods for ab- and c-type variables are calculated using the latest theoretical calibrations of log P_ab and log P_c as a function of luminosity, mass, effective temperature, and metallicity. Our models are generally able to reproduce the measured periods to well within the uncertainties implied by the stellar properties on which pulsation periods depend, as well as the mean periods and cluster-to-cluster differences in and , on the assumption of well-supported values of E(B-V), (m-M)_V, and [Fe/H]. While many of the RR Lyrae in M3 lie close to the same ZAHB that fits the faintest HB stars at bluer or redder colors, the M92 variables are all significantly evolved stars from ZAHB locations on the blue side of the instability strip. M15 appears to contain a similar populatio...

  15. Structural phase transition behaviour of Zn_4Sb_3 and its substitutional compounds(Zn_(0.98)M_(0.02))_4Sb_3(M=A1,Ga and In)at low temperatures

    Institute of Scientific and Technical Information of China (English)

    Liu Feng; Qin Xiao-Ying; Liu Mian

    2009-01-01

    Structural phase transitions of Zn_4Sb_3 and its substitutional compounds(Zn_(0.98)M_(0.02))_4Sb_3(M=A1, Ga and In)are investigated by electrical transport measurement and differential scanning calorimetry below room temperature. The results indicate that bothβ→α andα→α' phase transitions of Zn_4Sb_3 are reversible and exothermic processes, which may be explained as that both the transitions originate from the ordering of the disordered interstitial Zn and vacancies in regular sizes. The derived activation energies of β→αand α→α'phase transition processes for Zn_4Sb3 are E_1=3.9 eV and E_2=4.1 eV, respectively. Although no remarkable influence on activation energy E_2 is observedafter Al doping, Al substitution for Zn Causes El to increase to 4.6 eV, implying its suppression of β reversible αtransition to a great extent. Moreover, it is found that both β reversible α and α reversible α' transitions are completely prohibited by substitution of either In or Ga for Zn in Zn_4Sb_3.The underlying mechanisms for these phenomena are discussed.

  16. Catalytic properties of La0.8Sr0.2Co0.5M0.5O3 (M Co, Ni, Cu) in methane combustion1

    Science.gov (United States)

    Yue-Hui, Wu; Lai-Tao, Luo; Wei, Liu

    2010-03-01

    A set of perovskite-type catalysts of general formula La0.8Sr0.2Co0.5M0.5O3 (M = Co, Ni, Cu) were prepared by alanine solution combustion method and used successfully for the methane combustion. The property of these materials were characterized by XRD, and TPR measurements. The effects of transition-metal ions on site B on structure and performance of the catalysts were studied. The result indicated that the structure and catalytic activities of the catalysts can remarkably affect by transition-metal ions on site B, the decrease of the electrons filled in d orbitals in the atom on site B is propitious to increase the catalytic activity for methane combustion, and the sequences of catalysts activities are La0.8Sr0.2CoO3 τ; Ce0.8Sr0.2CoO3 τ; Nd0.8Sr0.2CoO3.

  17. 工业用3M圆弧齿同步带动力学仿真分析研究%Research on Dynamic Simulation Analysis of Industrial 3 M Arc Teeth Synchronous Belt

    Institute of Scientific and Technical Information of China (English)

    李占国; 李浩; 史尧臣; 应建立

    2015-01-01

    Considering industrial 3M arc teeth synchronous belt, this paper establishes a 3D model of synchronous belt and pulley by UG, makes a gridding division on the synchronous belt by HyperMesh, then builds a MFBD model of the belt and pulley by RecurDyn and carries out a dynamic simulation and analysis, to get the stress curve during the belt’ s driving, and it systematically analyzes the effects of different velocity of driving wheel and tension on the biggest stress, which provides a kind of digital simulation analysis meth-od for the industrial arc teeth synchronous belt life.%针对工业用3M圆弧齿同步带,利用UG软件建立同步带与带轮3D模型,通过HyperMesh软件对同步带进行网格划分,再利用RecurDyn软件建立带与带轮的刚柔耦合模型并进行动力学仿真分析,获得传动过程中带应力变化曲线,系统分析不同转速和张紧力对带最大应力影响规律。为研究工业用圆弧齿同步带的使用寿命提供了一种数字化仿真分析方法。

  18. Optical and fluorescence spectroscopy of Eu2O3-doped P2O5-K2O-KF-MO-Al2O3 (M = Mg, Sr and Ba) glasses

    Science.gov (United States)

    Kumar, K. Upendra; Babu, S. Surendra; Rao, Ch. Srinivasa; Jayasankar, C. K.

    2011-06-01

    Fluorophosphate glasses of composition, P2O5 + K2O + KF + MO + Al2O3 + xEu2O3 (M = Mg, Sr and Ba; x = 0.01, 0.05, 0.1, 1.0, 2.0, 4.0 and 6.0 mol%) were prepared and characterized their optical properties. Crystal-field (CF) analysis revealed a relatively weak CF strength around Eu3+ ions in the Ba based fluorophosphate glasses. The Judd-Ofelt parameters have been estimated from the oscillator strengths of 7F0 → 5D2, 7F0 → 5D4 and 7F0 → 5L6 absorption transitions of Eu3+ ions and were used to evaluate the radiative properties of the 5D0 → 7FJ (J = 0-4) transitions. Considerable variation has been observed in the relative intensity ratio of 5D0 → 7F2 to 5D0 → 7F1 transitions of Eu3+ ions due to change in the alkaline earth metal ions. The decay of the 5D0 level shows single exponential and less sensitive to Eu3+ ions concentration as well as MgO/SrO/BaO modifiers.

  19. Neutron and magnetic studies of L a0.7S r0.3M n1 -xC rxO3 (x ≤0.7 ) : A homogeneous charge-ordered system

    Science.gov (United States)

    Creel, Thomas F.; Yang, Jinbo; Malik, Satish K.; Quezado, S.; Pringle, O. A.; Yelon, William B.; James, William J.

    2016-02-01

    Structural and magnetic properties of L a0.7S r0.3M n1 -xC rxO3(0

  20. Refletindo sobre liderança em Enfermagem Reflexionando sobre liderazgo en enfermería Reflecting on nursing leadership

    Directory of Open Access Journals (Sweden)

    Mirtes Ribeiro

    2006-04-01

    Full Text Available Este estudo refletiu sobre as diversas formas de liderança. A liderança envolve relação interpessoal. A comunicação é indispensável nesse processo, pois através dela o enfermeiro troca conhecimento, organiza seu serviço, traçando objetivos junto a sua equipe. No exercício da liderança, o profissional deve propiciar um ambiente favorável para a execução das atividades no cotidiano de trabalho. A liderança torna-se essencial para a profissão, pois ter aptidão para comunicar, solucionar conflitos e ter iniciativa são atributos que contribuem para o cuidar.Este estudio reflexionó sobre las diversas formas de liderazgo. El liderazgo envuelve relación interpersonal. La comunicación es indispensable en ese proseso, pués através de ella el enfermero cambia el conocimiento, organiza su servicio trazando objetivos junto a su equipo. En el ejercicio del liderazgo, el profesional debe propiciar un ambiente favorable para la ejecución de las actividades en el cotidiano de trabajo. El liderazgo es esencial para la profesión, requiere actitud para comunicar, solucionar conflictos y tener de una iniciativa, son atributos que contribuyen para el cuidar.This study reflected on the diverse ways of leadership. The leadership involves interpersonal relationship. The communication is indispensable in this process, therefore through it the nurse exchanges knowledge, it organizes the nurses' service, tracing objective with the team. In the exercise of the leadership, the professional must propitiate a favorable environment for the execution of the activities in the daily work. The leadership becomes essential for the profession, therefore to have aptitude to communicate, to solve conflicts and to have initiative are attributes that contribute for the take care.

  1. Efecto de los extractos de Geranium ayavacense W. (Pasuchaca sobre la glicemia en ratas con diabetes mellitus experimental

    Directory of Open Access Journals (Sweden)

    José Aranda-Ventura

    2014-04-01

    Full Text Available Objetivos . Determinar si el extracto acuoso liofilizado de Geranium ayavacense (Pasuchaca tiene algún efecto sobre la glicemia en ratas con diabetes mellitus experimental. Materiales y métodos. La diabetes experimental fue inducida con aloxano. Las ratas cumplieron los criterios: glicemia > 200 mg/dL posadministración de aloxano y un peso > 200 g. Las ratas con diabetes experimental fueron distribuidas en seis grupos de ocho ratas cada uno. El grupo I recibió 3 mL de agua destilada (control; el grupo II recibió Geranium ayavacense 12,7 mg/kg; el grupo III recibió Geranium ayavacense 100 mg/kg; el grupo IV recibió Geranium ayavacense 200 mg/kg; el grupo V recibió Geranium ayavacense 300 mg/kg; el grupo VI recibió Geranium ayavacense 500 mg/kg. Se determinó la glicemia basal. Las evaluaciones de la glicemia se realizaron a la 1.ª, 3.ª, 6.ª, 12.ª y 24ª hora después de administrar las diferentes intervenciones. Resultados. Los grupos de Geranium ayavacense de 300 y 500 mg/kg disminuyeron significativamente (p<0,01 la glicemia en todas las horas evaluadas después de la administración de los extractos, cuando se compara con el grupo control. El grupo de Geranium ayavacense de 300 mg/kg decreció su glucosa sanguínea en 8,14; 10,68; 14,87; 19.36 y 23,7% a la 1.ª, 3.ª, 6.ª, 12.ª y 24.ª hora respectivamente. Conclusiones. En condiciones experimentales, el extracto acuoso de Geranium ayavacense tiene efecto hipoglicemiante en ratas

  2. Efecto de los extractos de Geranium ayavacense W. (Pasuchaca sobre la glicemia en ratas con diabetes mellitus experimental

    Directory of Open Access Journals (Sweden)

    José Aranda-Ventura

    2014-06-01

    Full Text Available Objetivos . Determinar si el extracto acuoso liofilizado de Geranium ayavacense (Pasuchaca tiene algún efecto sobre la glicemia en ratas con diabetes mellitus experimental. Materiales y métodos. La diabetes experimental fue inducida con aloxano. Las ratas cumplieron los criterios: glicemia > 200 mg/dL posadministración de aloxano y un peso > 200 g. Las ratas con diabetes experimental fueron distribuidas en seis grupos de ocho ratas cada uno. El grupo I recibió 3 mL de agua destilada (control; el grupo II recibió Geranium ayavacense 12,7 mg/kg; el grupo III recibió Geranium ayavacense 100 mg/kg; el grupo IV recibió Geranium ayavacense 200 mg/kg; el grupo V recibió Geranium ayavacense 300 mg/kg; el grupo VI recibió Geranium ayavacense 500 mg/kg. Se determinó la glicemia basal. Las evaluaciones de la glicemia se realizaron a la 1.ª, 3.ª, 6.ª, 12.ª y 24ª hora después de administrar las diferentes intervenciones. Resultados. Los grupos de Geranium ayavacense de 300 y 500 mg/kg disminuyeron significativamente (p<0,01 la glicemia en todas las horas evaluadas después de la administración de los extractos, cuando se compara con el grupo control. El grupo de Geranium ayavacense de 300 mg/kg decreció su glucosa sanguínea en 8,14; 10,68; 14,87; 19.36 y 23,7% a la 1.ª, 3.ª, 6.ª, 12.ª y 24.ª hora respectivamente. Conclusiones. En condiciones experimentales, el extracto acuoso de Geranium ayavacense tiene efecto hipoglicemiante en ratas

  3. Puente pretensado sobre el río Main

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    Wittfoht, Hans

    1965-04-01

    tablero es también circular, de 14.000 m de radio, con concavidad hacia arriba y parte más baja en las proximidades de la clave. El hormigonado de las dos vigas cajón que soportan las calzadas y andenes se ha realizado por un sistema mixto de voladizo y cimbra móvil apoyada sobre un entramado que se iba corriendo, a medida que avanzaba el brazo en voladizo, por trozos de 3,5 y hasta 7 m de longitud, iniciándose sobre un pilar y avanzando después simultáneamente a uno y otro lado del trozo inicial. El pretensado ha sido la parte principal del sistema mixto de construcción. La construcción por trozos y el gran número de cables longitudinales y transversales, ha exigido especial atención para sus anclajes y colocación. Con objeto de evitar la fisuración se procedió a colocar una serie de tubos en el interior del hormigón fresco, a modo de serpentín refrigerador, que absorbían su calor de hidratación durante el fraguado. Durante el período de construcción, la articulación prevista sobre los soportes se solidarizó con el cuerpo de la pila, constituyendo un todo monolítico con la estructura celular del brazo en voladizo.

  4. Propuesta de programa educativo sobre enfermedades del cuello uterino

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    Grisel Mariela Mass Basulto

    2011-12-01

    Full Text Available Fundamento: El cáncer ginecológico está entre las más frecuentes causas de muerte en la población femenina. En Cuba, el diagnóstico precoz de tal afección está entre los programas priorizados del Sistema de Salud Pública; pero también es necesario enfatizar en la prevención, que puede lograse, sobre todo, desde la atención primaria de salud, mediante la implementación de programas educativos. Objetivo: Diseñar un programa educativo sobre afecciones del cuello uterino. Métodos: Estudio descriptivo y retrospectivo, en el período comprendido del 1 de enero de 2008 al 1 de enero de 2009. Se analizaron variables como edad, escolaridad, primeras relaciones sexuales, número de partos, número de compañeros sexuales, uso de anticonceptivo, antecedentes de infecciones de transmisión sexual, hábitos tóxicos y nivel de conocimiento. Se aplicó el criterio de expertos para la validación de la propuesta educativa. Resultados: La mayoría de las mujeres tuvieron relaciones sexuales precoces, cuatro o más compañeros sexuales y eran fumadoras, mientras que el total de ellas había presentado alguna vez infecciones vaginales. El nivel de conocimiento que predominó fue regular. Conclusiones: Es evidente que en la población estudiada se concentran varios factores de riesgo para el cáncer de cuello uterino. El Programa Educativo sobre enfermedades del cuello uterino, fue validado mediante criterio de expertos, los cuales coincidieron en que tiene gran actualidad científica, congruencia interna y en que favorece el proceso de preparación de la mujer para evitar ese tipo de enfermedades.A Proposal for an Educational Program on Cervical DiseaseBackground: Gynecologic cancer is among the most frequent causes of death in women. In Cuba, early diagnosis of this condition is among the prioritized programs of the Public Health System, but it is also necessary to emphasize on prevention. This can be achieved especially in the primary health care

  5. Puente sobre el río Ain

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    Editorial, Equipo

    1963-02-01

    against the deforming effect of the wind.Como consecuencia de la construcción del nuevo embalse sobre el río Ain, las aguas de éste se han elevado considerablemente sobre los niveles asignados a la cota media de desagüe del puente suspendido existente en las inmediaciones de Serrières-sur-Ain. Por ello, se ha tenido que pensar en la sustitución de esta obra por otra moderna y de capacidad suficiente para las exigencias del tráfico actual. En este artículo se reseñan los datos más importantes de esta obra, entre los que, resumiendo, diremos que el nuevo puente salva el río con un arco de hormigón armado, de 120 m de luz, de intradós circular, tablero apoyado sobre una palizada levantada a partir del extradós del arco y con una flecha máxima de 30 m en la clave del arco. El tablero sostiene una calzada de 7 m de anchura y lleva dos andenes, de 1 m de anchura cada uno, para el paso de peatones.

  6. Constraints on the Distance Moduli, Helium and Metal Abundances, and Ages of Globular Clusters from their RR Lyrae and Non-variable Horizontal-branch Stars. I. M3, M15, and M92

    Science.gov (United States)

    VandenBerg, Don A.; Denissenkov, P. A.; Catelan, Márcio

    2016-08-01

    Up-to-date isochrones, zero-age horizontal-branch (ZAHB) loci, and evolutionary tracks for core He-burning stars are applied to the color–magnitude diagrams of M3, M15, and M92, focusing in particular on their RR Lyrae populations. Periods for the ab- and c-type variables are calculated using the latest theoretical calibrations of {log} {P}{ab} and {log} {P}c as a function of luminosity, mass, effective temperature ({T}{{eff}}), and metallicity. Our models are generally able to reproduce the measured periods to well within the uncertainties implied by the stellar properties on which pulsation periods depend, as well as the mean periods and cluster-to-cluster differences in and , on the assumption of well-supported values of E(B-V), {(m-M)}V, and [Fe/H]. While many of RR Lyrae in M3 lie close to the same ZAHB that fits the faintest horizontal-branch (HB) stars at bluer or redder colors, the M92 variables are all significantly evolved stars from ZAHB locations on the blue side of the instability strip. M15 appears to contain a similar population of HB stars as M92, along with additional helium-enhanced populations not present in the latter which comprise most of its RR Lyrae stars. The large number of variables in M15 and the similarity of the observed values of and in M15 and M92 can be explained by HB models that allow for variations in Y. Similar ages (∼12.5 Gyr) are found for all three clusters, making them significantly younger than the field halo subgiant HD 140283. Our analysis suggests a preference for stellar models that take diffusive processes into account.

  7. Consideraciones sobre la produccion de frutas en Venezuela

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    Jesús Aular

    2011-10-01

    Full Text Available En la presente revisión se presenta información sobre superficie, producción, y rendimiento de los frutales en Venezuela. Además se hacen consideraciones sobre los sistemas de producción, destacando limitaciones, avances y sugerencias. La fruticultura en Venezuela ocupa el 3er. lugar dentro del sector agrícola vegetal. Existen 167.691 Ha de frutales y una producción 2.232.088 TM por año. Se producen comercialmente una docena de rubros frutícolas, siendo los principales: plátano, banano, naranjo y piña. Las áreas de producción van desde zonas bajas y áridas, en donde se obtienen uvas y piñas; hasta zonas altas y húmedas donde se hallan duraznos y fresas. Ha habido reducción de la superficie plantada, con excepción de lechosa, piña y aguacate. El manejo hortícola de los huertos frutícolas es heterogéneo, ya que se observa desde bajo hasta alto nivel de tecnología. La incorrecta aplicación de las prácticas hortícolas origina baja productividad y calidad de fruta. La poscosecha podría mejorarse a través del desarrollo e implementación de normas de clasificación, empaque, embalaje, y cadena de frío. La exportación de frutas venezolanas se ha reducido en los últimos años y se concentra en mango, naranja y lima Tahití. Los principales destinos son Colombia, Europa, Norteamérica y las islas del Caribe. Sólo la naranja se procesa de manera importante en Venezuela. Las perspectivas para la fruticultura venezolana es continuar como una actividad dirigida al mercado interno, no se vislumbra una mayor participación del país en el mercado internacional.

  8. Los estudios sobre el ambiente y la ciencia ambiental

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    Amelia Nancy Giannuzzo

    2010-03-01

    Full Text Available La existencia de la ciencia ambiental es reconocida en libros, revistas de publicación científica y carreras de grado y posgrado. Sin embargo, se desconoce su existencia en forma literal o indirecta, al no ser considerado su aporte, por ejemplo, en los planteos referidos sobre la ciencia y la tecnología de la sustentabilidad. En este trabajo se presentan estos antecedentes, relacionándolos con el objetivo del mismo, que es el de aportar a la dilucidación de la existencia y conformación de la ciencia ambiental. Para esto, se analiza la relación de las disciplinas con la dimensión compleja del ambiente como objeto de estudio y aspectos metodológicos derivados. A los fines de aportar al esclarecimiento conceptual, se identifican las distintas acepciones de ambiente comúnmente referidas en la bibliografía. Además, se discuten aspectos relacionados de multidisciplinariedad, interdisciplinariedad y transdisciplinariedad, y sobre el status epistémico de la ciencia ambiental. Se concluye que una mayor precisión conceptual embasada en un marco compartido por las disciplinas que estudian el ambiente, incluida la ciencia ambiental, y los distintos actores involucrados en las problemáticas ambientales, favorecerá el refinamiento de las metodologías tendientes a disminuir la fragmentación de las investigaciones concernientes y las aplicaciones para su resolución.The existence of an environmental science is recognized in books, journals of science as well as in undergraduate and graduate studies. Its existence, however, is unknown either literally or indirectly when, for instance, its contribution to topics connected to the science and technology of sustainability is not considered. This background is presented in this paper and connected to its objective, which is to elucidate the existence and structure of the environmental science. To this goal, I analyse the relationship of the disciplines with the complex dimension of the environment

  9. Informe sobre la violencia en América Latina

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    Pierre Salama

    2008-06-01

    Full Text Available ¿Es por la pobreza, por las enorme desigualdades en materia de ingreso o por sus evoluciones respectivas que la violencia ha alcanzado cifras record en muchos países de América Latina? ¿Es debido a la insuficiente represión, a las escasas tropas de policía, a la gran ineficiencia de la justicia o a su extrema laxitud que se desencadena la violencia? ¿Es a causa de las recientes guerras civiles, de las dictaduras que han dejado profundas huellas en el comportamiento, tanto de las fuerzas del orden como de los ciudadanos, que la violencia se mantiene en un nivel tan elevado? ¿Es porque poblaciones enteras han sido excluidas, y sus culturas y sus identidades ignoradas, que las sociedades se encuentren tan poco cohesionadas y que se desarrolle la violencia? ¿Es debido a la producción y comercialización de las drogas que la violencia es tan elevada?El propósito de este artículo es analizar los factores que inducen a tales tipos de violencia. La reducción de la violencia en el mediano y en el largo plazo requiere un cierto número de prerrequisitos para lograr una sociedad más cohesionada: disminuir sustancialmente las desigualdades socioeconómicas, promover una redistribución más equitativa, desarrollar una educación primaria y profesional de calidad, mejorar la calidad de las instituciones, particularmente y sobre todo, las de justicia y policía, e inventar políticas urbanas. Es en este contexto que se inscriben las “soluciones culturales”, por medio de políticas urbanas pero, sobre todo, y muy particularmente, en cierto número de países, el reconocimiento de los derechos y valores, ignorados durante mucho tiempo, de poblaciones completas. Esta es la dificultad y la magnitud de las tareas, sin la cual una política de represión no sabría ser eficaz.

  10. Coxins interfalangeanos sobre paquidermodactilia Interphalangeal pads on pachydermodactyly

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    José Marcos Pereira

    2004-05-01

    Full Text Available Coxins interfalangeanos são nodulações ceratósicas, de limites precisos, com aproximadamente um centímetro de diâmetro, geralmente sobre as articulações interfalangenas das mãos. A paquidermodactilia é uma tumefação uniforme da pele que ocorre nas falanges proximais das mãos. É relatado o caso de um jovem com associação de paquidermodactilia e coxins interfalangeanos, fato não encontrado na literatura médica. Embora haja descrição que considera serem essas manifestações diversas da mesma doença, acredita-se que sejam entidades distintas. O ato compulsivo de atritar a pele parece ser o denominador comum mais aceito para justificar as duas doenças. Os autores postulam que o coxim interfalangeano seria uma resposta epidérmica, enquanto a paquidermodactilia, uma resposta dérmica a um mesmo fator traumático sobre a pele. O paciente foi tratado com infiltração intralesional de triancinolona, com melhora clínica expressiva das duas manifestações.Knuckle pads are keratotic nodulations within precise limits and approximately one centimeter in diameter, usually on the interphalangeal joints of the hands. Pachydermodactyly is a uniform swelling of the skin occurring in the proximal phalanges of the hands. A case involving a young man suffering from several knuckle pad lesions concomitant with pachydermodactyly was studied. This association has not been previously described in the literature. Although it has been reported that both conditions are different manifestations of the same disease, they are believed to be distinct disorders. The compulsive act of rubbing the skin seems to be a common denominator mostly accepted as the cause of both diseases. The authors affirm that knuckle pads may be acquired as an epidermal response, while pachydermodactyly, is a dermal response to the same traumatic factor to the skin. The patient was treated with intralesional infiltration of triamcinolone resulting in a remarkable clinical

  11. Base de datos sobre necesidades hídricas

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    Felicita González Robaina

    2012-01-01

    Full Text Available El ordenamiento y accesibilidad a la información sobre régimen hídrico de los principales cultivos agrícolas resulta de gran impacto económico social ya que la misma permite la definición de la función agua rendimiento y la productividad del agua como herramientas eficientes en el planeamiento, diseño y operación del suministro de agua a los cultivos. Este trabajo se trazó como objetivo obtener a partir de la recopilación y tabulación de los resultados experimentales existentes en el Instituto de Investigaciones de Riego y Drenaje (IIRD, una base de datos sobre necesidades hídricas de algunos cultivos de interés agrícola. La base de datos comprende la información experimental de 1971 hasta 2009, más de 22 cultivos, cinco tipos de suelos, con diferentes técnicas de riego y un rango amplio de tratamientos de riego. Así como las variables: evaporación, consumo de agua, rendimientos, número de riegos, agua aplicada por riego, precipitaciones reportadas, lluvia aprovechable. Esta base de datos permitirá en etapas posteriores determinar para cultivos de interés su potencial de producción, así como la productividad agronómica del agua y el factor de respuesta del rendimiento como expresión de la función agua rendimiento; contribuyendo a la definición de estrategias que den respuesta al problema de la escasez de agua y a la seguridad alimentaria a un costo ambiental más bajo. Se programó la base de datos para su colocación en la página WEB del Instituto de Investigaciones de Ingeniería Agrícola (IAgric como parte del sistema de asesoramiento al regante y su consulta por parte de todos los usuarios interesados.

  12. Efectos del vendaje neuromuscular sobre la flexibilidad del raquis lumbar

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    A.M. Labrador-Cerrato

    2015-03-01

    Full Text Available Introducción: El vendaje neuromuscular es una técnica que produce una estimulación muy selectiva sobre la piel a través de la aplicación de unas vendas elásticas especiales con el fin de lograr cambios propioceptivos, aumento o inhibición del tono muscular y mitigación de algias, entre otros. Objetivos: Comprobar si la aplicación del vendaje neuromuscular permite aumentar la flexión del raquis lumbar comparándola con otras técnicas de vendaje placebo (esparadrapo rígido convencional; Omniplaste®-E; observar la concordancia entre la prueba sit-and-reach y el test de Schober en la valoración de la ganancia de flexión lumbar. Material y métodos: Estudio piloto experimental a triple ciego. Se distribuyeron aleatoriamente 45 sujetos sanos de 20-55 años en tres grupos: 1 esparadrapo convencional; 2 Omniplaste®-E; 3 vendaje neuromuscular. En todos los participantes se evaluó la flexión del raquis lumbar mediante la prueba sit-and-reach y el test de Schober antes y después de la intervención siguiendo el mismo protocolo. Resultados: Considerado un intervalo de confianza del 95% y grado de significación estadística p<0,05 en todos los casos, se obtuvo un incremento estadísticamente significativo de la flexión lumbar en todos los grupos según la prueba sit-and-reach, que fue mayor en el grupo del vendaje neuromuscular (1,5 cm de mediana; p=0,011. Según el test de Schober, solamente el vendaje neuromuscular se mostró eficiente (p<0,001, incrementándose el valor basal en un 6,25% (1 cm de mediana. Conclusiones: La aplicación del vendaje neuromuscular sobre la columna lumbar mejora la flexión lumbar respecto a técnicas placebo a partir de los resultados obtenidos mediante el test de Schober, así como una mayor flexión global del tronco que estas técnicas según la prueba sit-and-reach. El test de Schober parece ser más fiable y preciso que la prueba sit-and-reach para estudios de este tipo.

  13. Diálogo sobre el Dios escondido. La búsqueda de Dios

    OpenAIRE

    Cusa, N. (Nicolás) de

    2011-01-01

    EL OPÚSCULO DIÁLOGO SOBRE EL DIOS ESCONDIDO El breve, y también maravilloso, escrito Diálogo sobre el Dios escondido (también denominado a veces con el nombre entero del Diálogo de un gentil y un cristiano sobre el Dios escondido) fue redactado por Nicolás de Cusa entre 1440 y 1445; se sitúa entre esas fechas, porque se sabe que es posterior a La docta ignorancia y previo a La búsqueda de Dios; suele considerarse que es el primer diálogo que escribió el Cusano1 da seguridad, es...

  14. Influencia de la lactancia materna sobre el desarrollo psicomotor y mental del niño

    OpenAIRE

    Gómez Sanchiz, Manuela

    2003-01-01

    En 1929 Hoefer y Hardy plantearon la hipótesis que la lactancia materna influía sobre el desarrollo mental del niño, además del físico. Los resultados de las investigaciones realizadas en esta área, hasta el momento, son contradictorios; no obstante una meta-análisis publicado en el año 1999 concluye que la lactancia materna influye positivamente sobre el desarrollo mental del niño, tanto a término como pretérmino. El objetivo del estudio fue analizar los efectos de la lactancia materna sobre...

  15. Indagando sobre el papel de la tecnología en el aula

    OpenAIRE

    Gavilán-Izquierdo, José María

    2014-01-01

    En este trabajo abordamos la problemática de investigación sobre el papel de la tecnología en el aula, centrándonos en el profesor. Utilizaremos la complementariedad entre dos ideas socioculturales, orquestación instrumental y modelación de la descomposición genética de un concepto, para aproximarnos a la caracterización del papel de la tecnología en el aula. Reflexionamos sobre la aportación que esta complementariedad hace a la discusión sobre la articulación de marcos teóricos...

  16. Efeito da mono-semi-carbazona do adrenocromo sobre o metabolismo de frangos de corte

    OpenAIRE

    Andriguetto, Jose Luciano

    2012-01-01

    Este estudo foi planejado com o objetivo de verificar o efeito da mono-semi-carbazona do adrenocromo (MSCA), um derivado estável do adrenocromo, sobre o metabolismo de frangos de corte, machos e fêmeas. A MSCA foi pouco pesquisada em termos de sua atividade sobre o organismo animal, inexistindo estudos da ação de substância em frangos de corte. Os efeitos da MSCA sobre o metabolismo de frangos de corte foram avaliados através da performance produtiva das aves e por acompanhamento da atividade...

  17. La literatura sobre la industrialización colombiana: Balance y perspectivas

    OpenAIRE

    Paulo César León Palacios

    2004-01-01

    Este artículo presenta una revisión extensa y analítica de la literatura producida sobre el tema de la industria en Colombia, a través de los ámbitos teórico, metodológico y gnoseológico. Es una referencia necesaria tanto para expertos, en tanto propone un debate global y crítico sobre el tema, como para estudiantes o investigadores que deseen tener una visión panorámica del estado del arte sobre la industrialización sin tener que sumergirse más de lo necesario.

  18. Investigación documental sobre la vida y obra de Científicos Holguineros

    OpenAIRE

    Jandy Alí Sánchez; Edith Guerra Ávila; Marisol Leyva Ruiz; Cecilia Fernández Peña

    2010-01-01

    Se muestran los resultados de la realización del Proyecto Territorial sobre la vida y obra de las personalidades investigadas y se argumenta la revisión bibliográfica sobre la elaboración de metodologías y la que se confeccionó y aplicó posteriormente. Se consultaron diferentes Fuentes de Información en distintos portadores con el objetivo de realizar un estudio bibliográfico sobre científicos holguineros, resaltando aspectos novedosos de su vida y obra y destacando los aportes alcanzados en ...

  19. Conhecimento, opinião e conduta de ginecologistas e obstetras brasileiros sobre o aborto induzido

    OpenAIRE

    Faúndes Aníbal; Duarte Graciana Alves; Andalaft Neto Jorge; Olivatto Adriane Elisabeth; Simoneti Rosana Martins

    2004-01-01

    OBJETIVO: avaliar conhecimento, opinião e conduta de ginecologistas e obstetras sobre o aborto induzido. MÉTODO: questionário estruturado e pré-testado foi enviado a ginecologistas e obstetras associados a FEBRASGO. Solicitou-se preenchê-lo sem identificar-se e retorná-lo em envelope pré-selado que o acompanhava, para assegurar anonimato. Perguntou-se sobre conhecimento da legalidade do aborto no Brasil, opinião sobre a mesma e conduta em situações de solicitação de aborto. RESULTADOS: para 9...

  20. Una nota sobre formación y formalismo del contrato electrónico

    Directory of Open Access Journals (Sweden)

    Silvana Fortich

    2011-07-01

    Full Text Available Este artículo pretende llamar la atención sobre algunas de las particularidades que presenta la celebración de contratos por medios electrónicos, indagando sobre las características propias de su formación y sobre la influencia del proceso general de renacimiento del formalismo en el campo del comercio electrónico. El estudio es realizado con base en las normas del derecho contemporáneo francés y colombiano que se ocupan de regular la materia.