WorldWideScience

Sample records for 3he apparent diffusion

  1. Simultaneous measurement of pulmonary partial pressure of oxygen and apparent diffusion coefficient by hyperpolarized 3He MRI

    OpenAIRE

    Yu, Jiangsheng; Law, Michelle; Kadlecek, Stephen; Emami, Kiarash; Ishii, Masaru; Stephen, Michael; Woodburn, John M.; Vahdat, Vahid; Rizi, Rahim R.

    2009-01-01

    Hyperpolarized 3He (HP 3He) MRI shows promise to assess structural and functional pulmonary parameters in a sensitive, regional and non-invasive way. Structural HP 3He MRI has applied the apparent diffusion coefficient (ADC) for the detection of disease-induced lung microstructure changes at the alveolar level, and HP 3He pulmonary partial pressure of oxygen (pO2) imaging measures the oxygen transfer efficiency between the lung and blood stream. Although both parameters are affected in chroni...

  2. Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva;

    2008-01-01

    PURPOSE: To compare apparent diffusion coefficient (ADC) measurements from hyperpolarized (HP) helium ((3)He)-magnetic resonance imaging (MRI) with quantitative data from multislice Computed Tomography (CT) (MSCT) of the whole lungs and pulmonary function tests (PFT). MATERIALS AND METHODS: Twenty...

  3. Hyperpolarized 3He apparent diffusion coefficient MRI of the lung: reproducibility and volume dependency in healthy volunteers and patients with emphysema

    DEFF Research Database (Denmark)

    Diaz, S.; Casselbrant, I.; Piitulainen, E.;

    2008-01-01

    PURPOSE: To measure the apparent diffusion coefficient (ADC) of hyperpolarized (HP) (3)He gas using diffusion weighted MRI in healthy volunteers and patients with emphysema and examine the reproducibility and volume dependency. MATERIALS AND METHODS: A total of eight healthy volunteers and 16...... in mean ADC with increased inhaled gas volume was observed in both groups. CONCLUSION: Mean ADC and SD of HP (3)He MRI is reproducible and discriminates well between healthy controls and patients with emphysema at the higher gas volume. This method is robust and may be useful to gain new insights...

  4. Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva;

    2008-01-01

    . Correlations between mean ADC and EI and 15th percentile were both r=0.90 and for MLD r=0.59. There was higher correlation between mean ADC and %predicted DLCO (r=0.90) than between EI and %predicted DLCO (r=0.76). CONCLUSION: HP (3)He-MRI correlates well with density measurements from MSCT and agrees better...

  5. Hyperpolarized 3He and 129Xe magnetic resonance imaging apparent diffusion coefficients: physiological relevance in older never‐ and ex‐smokers

    Science.gov (United States)

    Kirby, Miranda; Ouriadov, Alexei; Svenningsen, Sarah; Owrangi, Amir; Wheatley, Andrew; Etemad‐Rezai, Roya; Santyr, Giles E.; McCormack, David G.; Parraga, Grace

    2014-01-01

    Abstract Noble gas pulmonary magnetic resonance imaging (MRI) is transitioning away from 3He to 129Xe gas, but the physiological/clinical relevance of 129Xe apparent diffusion coefficient (ADC) parenchyma measurements is not well understood. Therefore, our objective was to generate 129Xe MRI ADC for comparison with 3He ADC and with well‐established measurements of alveolar structure and function in older never‐smokers and ex‐smokers with chronic obstructive pulmonary disease (COPD). In four never‐smokers and 10 COPD ex‐smokers, 3He (b = 1.6 sec/cm2) and 129Xe (b = 12, 20, and 30 sec/cm2) ADC, computed tomography (CT) density‐threshold measurements, and the diffusing capacity for carbon monoxide (DLCO) were measured. To understand regional differences, the anterior–posterior (APG) and superior–inferior (∆SI) ADC differences were evaluated. Compared to never‐smokers, COPD ex‐smokers showed greater 3He ADC (P = 0.006), 129Xe ADCb12 (P = 0.006), and ADCb20 (P = 0.006), but not for ADCb30 (P > 0.05). Never‐smokers and COPD ex‐smokers had significantly different APG for 3He ADC (P = 0.02), 129Xe ADCb12 (P = 0.006), and ADCb20 (P = 0.01), but not for ADCb30 (P > 0.05). ∆SI for never‐ and ex‐smokers was significantly different for 3He ADC (P = 0.046), but not for 129Xe ADC (P > 0.05). There were strong correlations for DLCO with 3He ADC and 129Xe ADCb12 (both r = −0.95, P < 0.05); in a multivariate model 129Xe ADCb12 was the only significant predictor of DLCO (P = 0.049). For COPD ex‐smokers, CT relative area <−950 HU (RA950) correlated with 3He ADC (r = 0.90, P = 0.008) and 129Xe ADCb12 (r = 0.85, P = 0.03). In conclusion, while 129Xe ADCb30 may be appropriate for evaluating subclinical or mild emphysema, in this small group of never‐smokers and ex‐smokers with moderate‐to‐severe emphysema, 129Xe ADCb12 provided a physiologically appropriate estimate of gas exchange abnormalities and alveolar microstructure. PMID:25347853

  6. Magnetization and spin diffusion of liquid 3He in aerogel

    International Nuclear Information System (INIS)

    We report theoretical calculations and experimental measurements of the normal-state spin diffusion coefficient of 3He in aerogel, including both elastic and inelastic scattering of 3He quasiparticles, and compare these results with data for 3He in 98% porous silica aerogel. This analysis provides a determination of the elastic mean free path within the aerogel. Measurements of the magnetization of the superfluid phase in the same aerogel samples provide a test of the theory of pairbreaking and magnetic response of low-energy excitations in the 'dirty' B phase of 3He in aerogel. A consistent interpretation of the data for the spin-diffusion coefficient, magnetization, and superfluid transition temperature is obtained by including correlation effects in the aerogel density

  7. Phase-contrast MRI and CFD modeling of apparent 3He gas flow in rat pulmonary airways

    Science.gov (United States)

    Minard, Kevin R.; Kuprat, Andrew P.; Kabilan, Senthil; Jacob, Richard E.; Einstein, Daniel R.; Carson, James P.; Corley, Richard A.

    2012-08-01

    Phase-contrast (PC) magnetic resonance imaging (MRI) with hyperpolarized 3He is potentially useful for developing and testing patient-specific models of pulmonary airflow. One challenge, however, is that PC-MRI provides apparent values of local 3He velocity that not only depend on actual airflow but also on gas diffusion. This not only blurs laminar flow patterns in narrow airways but also introduces anomalous airflow structure that reflects gas-wall interactions. Here, both effects are predicted in a live rat using computational fluid dynamics (CFD), and for the first time, simulated patterns of apparent 3He gas velocity are compared with in vivo PC-MRI. Results show (1) that correlations (R2) between measured and simulated airflow patterns increase from 0.23 to 0.79 simply by accounting for apparent 3He transport, and (2) that remaining differences are mainly due to uncertain airway segmentation and partial volume effects stemming from relatively coarse MRI resolution. Higher-fidelity testing of pulmonary airflow predictions should therefore be possible with future imaging improvements.

  8. Phase-Contrast MRI and CFD Modeling of Apparent 3He Gas Flow in Rat Pulmonary Airways

    International Nuclear Information System (INIS)

    Phase-contrast (PC) magnetic resonance imaging (MRI) with hyperpolarized 3He is potentially useful for developing and testing patient-specific models of pulmonary airflow. One challenge, however, is that PC-MRI provides apparent values of local 3He velocity that not only depend on actual airflow but also on gas diffusion. This not only blurs laminar flow patterns in narrow airways but also introduces anomalous airflow structure that reflects gas-wall interactions. Here, both effects are predicted in a live rat using computational fluid dynamics (CFD), and for the first time, simulated patterns of apparent 3He gas velocity are compared with in-vivo PC-MRI. Results show (1) that correlations (R2) between measured and simulated airflow patterns increase from 0.23 to 0.79 simply by accounting for apparent 3He transport, and that (2) remaining differences are mainly due to uncertain airway segmentation and partial volume effects stemming from relatively coarse MRI resolution. Higher-fidelity testing of pulmonary airflow predictions should therefore be possible with future imaging improvements.

  9. Phase-Contrast MRI and CFD Modeling of Apparent 3He Gas Flow in Rat Pulmonary Airways

    Energy Technology Data Exchange (ETDEWEB)

    Minard, Kevin R.; Kuprat, Andrew P.; Kabilan, Senthil; Jacob, Rick E.; Einstein, Daniel R.; Carson, James P.; Corley, Richard A.

    2012-08-01

    Phase-contrast (PC) magnetic resonance imaging (MRI) with hyperpolarized 3He is potentially useful for developing and testing patient-specific models of pulmonary airflow. One challenge, however, is that PC-MRI provides apparent values of local 3He velocity that not only depend on actual airflow but also on gas diffusion. This not only blurs laminar flow patterns in narrow airways but also introduces anomalous airflow structure that reflects gas-wall interactions. Here, both effects are predicted in a live rat using computational fluid dynamics (CFD), and for the first time, simulated patterns of apparent 3He gas velocity are compared with in-vivo PC-MRI. Results show (1) that correlations (R2) between measured and simulated airflow patterns increase from 0.23 to 0.79 simply by accounting for apparent 3He transport, and that (2) remaining differences are mainly due to uncertain airway segmentation and partial volume effects stemming from relatively coarse MRI resolution. Higher-fidelity testing of pulmonary airflow predictions should therefore be possible with future imaging improvements.

  10. In vivo lung morphometry with hyperpolarized 3He diffusion MRI: Theoretical background

    Science.gov (United States)

    Sukstanskii, A. L.; Yablonskiy, D. A.

    2008-02-01

    MRI-based study of 3He gas diffusion in lungs may provide important information on lung microstructure. Lung acinar airways can be described in terms of cylinders covered with alveolar sleeve [Haefeli-Bleuer, Weibel, Anat. Rec. 220 (1988) 401]. For relatively short diffusion times (on the order of a few ms) this geometry allows description of the 3He diffusion attenuated MR signal in lungs in terms of two diffusion coefficients—longitudinal (D) and transverse (D) with respect to the individual acinar airway axis [Yablonskiy et al., PNAS 99 (2002) 3111]. In this paper, empirical relationships between D and D and the geometrical parameters of airways and alveoli are found by means of computer Monte Carlo simulations. The effects of non-Gaussian signal behavior (dependence of D and D on b-value) are also taken into account. The results obtained are quantitatively valid in the physiologically important range of airway parameters characteristic of healthy lungs and lungs with mild emphysema. In lungs with advanced emphysema, the results provide only "apparent" characteristics but still could potentially be used to evaluate emphysema progression. This creates a basis for in vivo lung morphometry—evaluation of the geometrical parameters of acinar airways from hyperpolarized 3He diffusion MRI, despite the airways being too small to be resolved by direct imaging. These results also predict a rather substantial dependence of 3He ADC on the experimentally-controllable diffusion time, Δ. If Δ is decreased from 3 ms to 1 ms, the ADC in normal human lungs may increase by almost 50%. This effect should be taken into account when comparing experimental data obtained with different pulse sequences.

  11. Emphysematous changes and normal variation in smokers and COPD patients using diffusion 3He MRI

    International Nuclear Information System (INIS)

    Introduction: This study aims to quantify global and regional changes of diffusive motion of 3He gas within the lung, as determined by hyperpolarized 3He MR apparent diffusion coefficient (ADC) measurement, in non-smokers, smokers and chronic obstructive pulmonary disease (COPD) patients. Methods: Age-matched groups of six healthy non-smokers, five healthy smokers and five patients with COPD. The experiments were performed with approval from the local Research Ethics Committee. Diffusion imaging was performed following hyperpolarized 3He gas inhalation, producing ADC maps. Mean and standard deviation of the ADCs were used to compare the subject groups and assess regional variations within individuals. Results: The intra-individual standard deviation of ADC in the healthy smokers was significantly larger than that of the non-smoking group (P < 0.02). Compared to the non-smoking group, COPD patients had significantly higher mean and standard deviation of ADC (P < 0.01). The mean ADC in the anterior half of the chest was systematically higher than in the posterior half in the healthy non-smoking subject group. Discussion: This study suggests that there are regional trends in the ADC values of healthy volunteers that may have implications for the clinical interpretation of ADC values. Less homogeneous ADC values have been detected in asymptomatic smokers, indicative of damage to the distal air spaces

  12. Magnetization and Spin-Diffusion of Liquid 3He in Aerogel

    OpenAIRE

    Sauls, J. A.; Bunkov, Yu. M.; Collin, E.; Godfrin, H.; Sharma, P

    2004-01-01

    We report theoretical calculations of the normal-state spin diffusion coefficient of 3He in aerogel, including both elastic and inelastic scattering of 3He quasiparticles, and compare these results with experimental data for 3He in 98% porous silica aerogel. This analysis provides a determination of the elastic mean free path within the aerogel. Measurements of the magnetization of the superfluid phase provide a test of the theory of pairbreaking and magnetic response of low-energy excitation...

  13. 3D MRI of non-Gaussian 3He gas diffusion in the rat lung

    Science.gov (United States)

    Jacob, Richard E.; Laicher, Gernot; Minard, Kevin R.

    2007-10-01

    In 3He magnetic resonance images of pulmonary air spaces, the confining architecture of the parenchymal tissue results in a non-Gaussian distribution of signal phase that non-exponentially attenuates image intensity as diffusion weighting is increased. Here, two approaches previously used for the analysis of non-Gaussian effects in the lung are compared and related using diffusion-weighted 3He MR images of mechanically ventilated rats. One approach is model-based and was presented by Yablonskiy et al., while the other approach utilizes the second order decay contribution that is predicted from the cumulant expansion theorem. Total lung coverage is achieved using a hybrid 3D pulse sequence that combines conventional phase encoding with sparse radial sampling for efficient gas usage. This enables the acquisition of nine 3D images using a total of only ˜1 L of hyperpolarized 3He gas. Diffusion weighting ranges from 0 s/cm 2 to 40 s/cm 2. Results show that the non-Gaussian effects of 3He gas diffusion in healthy rat lungs are directly attributed to the anisotropic geometry of lung microstructure as predicted by the Yablonskiy model, and that quantitative analysis over the entire lung can be reliably repeated in time-course studies of the same animal.

  14. NMR measurements of hyperpolarized 3He gas diffusion in high porosity silica aerogels

    OpenAIRE

    Tastevin, Geneviève; Nacher, Pierre-Jean

    2005-01-01

    Hyperpolarized 3He is used to nondestructively probe by NMR the structure of custom-made and commercial silica aerogels (97% and 98.5% porous). Large spin-echo signals are obtained at room temperature and very low magnetic field (2mT) even with small mounts of gas. Attenuation induced by applied field gradients results from the combined effects of gas diffusion and confinement by the porous medium on atomic motion. Nitrogen is used as a buffer gas to reach equivalent 3He pressures ranging fro...

  15. Dynamical Behavior of Core 3 He Nuclear Reaction-Diffusion Systems and Sun's Gravitational Field

    Institute of Scientific and Technical Information of China (English)

    DU Jiulin; SHEN Hong

    2005-01-01

    The coupling of the sun's gravitational field with processes of diffusion and convection exerts a significant influence on the dynamical behavior of the core 3He nuclear reaction-diffusion system. Stability analyses of the system are made in this paper by using the theory of nonequilibrium dynamics. It is showed that, in the nuclear reaction regions extending from the center to about 0.38 times of the radius of the sun, the gravitational field enables the core 3He nuclear reaction-diffusion system to become unstable and, after the instability, new states to appear in the system have characteristic of time oscillation. This may change the production rates of both 7Be and 8B neutrinos.

  16. Response to Commentary on "The influence of lung airways branching structure and diffusion time on measurements and models of short-range 3He gas MR diffusion".

    Science.gov (United States)

    Parra-Robles, Juan; Wild, Jim M

    2014-02-01

    Our extensive investigation of the cylinder model theory through numerical modelling and purpose-designed experiments has demonstrated that it does produce inaccurate estimates of airway dimensions at all diffusion times currently used. This is due to a variety of effects: incomplete treatment of non-Gaussian effects, finite airway size, branching geometry, background susceptibility gradients and diffusion time dependence of the (3)He MR diffusion behaviour in acinar airways. The cylinder model is a good starting point for the development of a lung morphometry technique from (3)He diffusion MR but its limitations need to be understood and documented in the interest of reliable clinical interpretation. PMID:24342570

  17. Radiation-damage-controlled He diffusion and 4He/3He spectra in apatite: an example of mutually consistent results from the Grand Canyon (Invited)

    Science.gov (United States)

    Farley, K. A.; Flowers, R. M.

    2009-12-01

    Recent work indicates that He diffusion from apatite is impeded by the accumulation of radiation damage from actinide decay. Supporting evidence includes laboratory diffusion measurements as well as (U-Th)/He dates positively correlated with effective uranium (eU) concentration in certain geologic situations. Here we investigate whether the radiation damage effect can be identified in 4He concentration profiles, as it must be if the system behaves as we anticipate. Apatites from nearby igneous basement samples in the Upper Gorge of the Grand Canyon showing a strong date-eU correlation were proton irradiated, step-heated, and analyzed for 4He/3He spectra. The low eU apatites with younger He dates yielded nearly flat spectra, while the high eU apatites with older He dates yielded highly rounded spectra (see Figure). This implies that the higher eU apatites were partially retaining He while the lower eU apatites were still acting as an open system. Using the RDAAM kinetic model (Flowers et al. 2009) and local geologic constraints we confirm that this behavior is consistent with the observed differences in date and eU, providing compelling evidence that both the He dates and the 4He profiles are sensitive to radiation damage accumulation. Equally importantly, the combination of multiple samples with differing eU and thus differing 4He/3He spectra yields remarkably tight constraints on the time-temperature path experienced by these rocks, from ~90oC down to < 30oC.

  18. Tritium/ 3He dating of shallow groundwater

    Science.gov (United States)

    Schlosser, Peter; Stute, Martin; Dörr, Helmut; Sonntag, Christian; Münnich, Karl Otto

    1988-08-01

    Combined tritium/ 3He data from three multi-level sampling wells (DFG 1, DFG 4, DFG 7) located at Liedern/ Bocholt, West Germany, are presented and principles of the tritium/ 3He method in shallow groundwater studies are discussed. The 3He excess produced by radioactive decay of bomb tritium (released mainly between 1952 and 1963) is clearly reflected in the data. The tritiogenic 3He signal can be detected with a good resolution (signal/1σ error: ≈ 350). The confinement of the tritiogenic 3He is estimated to approximately 77-85% at site DFG 4. For the bomb tritium peak the deviation of the tritium/ 3He age from the age determined by identifying the groundwater layer recharged between 1962 and 1965 is about 3 years (15%). The deviation can be explained by diffusive 3He loss across the groundwater table and by flow dispersion.

  19. Apparent diffusion coefficient correlation with oesophageal tumour stroma and angiogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Aoyagi, Tomoyoshi; Shuto, Kiyohiko; Okazumi, Shinichi; Hayano, Kohichi; Satoh, Asami; Saitoh, Hiroshige; Shimada, Hideaki; Nabeya, Yoshihiro; Matsubara, Hisahiro [Chiba University, Department of Frontier Surgery, Graduate School of Medicine, Chiba (Japan); Kazama, Toshiki [Chiba University, Department of Radiology, Graduate School of Medicine, Chiba (Japan)

    2012-06-15

    Because diffusion-weighted imaging (DWI) can predict the prognosis of patients with oesophageal squamous cell carcinoma (ESCC), we hypothesised that apparent diffusion coefficient (ADC) values might be correlated with the collagen content and tumour angiogenesis. The purpose of this study was to determine the correlation between ADC values of ESCC before treatment and oesophageal tumour stroma and angiogenesis. Seventeen patients with ESCC were enrolled. The ADC values were calculated from the DWI score. Seventeen patients who had undergone oesophagectomy were analysed for tumour stroma, vascular endothelial growth factor (VEGF) and CD34. Tissue collagen was stained with azocarmine and aniline blue to quantitatively analyse the extracellular matrix in cancer stroma. Tissues were stained with VEGF and CD34 to analyse the angiogenesis. The ADC values decreased with stromal collagen growth. We found a negative correlation between the tumour ADC and the amount of stromal collagen (r = -0.729, P = 0.001), i.e. the ADC values decreased with growth of VEGF. We also found a negative correlation between the ADC of the tumours and the amount of VEGF (r = 0.538, P = 0.026). Our results indicated that the ADC value may be a novel prognostic factor and contribute to the treatment of oesophageal cancer. circle Magnetic resonance apparent diffusion coefficient values inversely indicate tumour stromal collagen circle There is also negative correlation between ADCs and vascular endothelial growth factor circle ADC values may contribute to the treatment of oesophageal cancer. (orig.)

  20. Apparent diffusion coefficient measurements in progressive supranuclear palsy

    International Nuclear Information System (INIS)

    We measured the apparent diffusion coefficient (ADC), using diffusion-weighted imaging (DWI) and signal intensity on T2-weighted MRI in the cerebral white matter of patients with progressive supranuclear palsy (PSP) and age-matched normal subjects. In PSP, ADC in the prefrontal and precentral white matter was significantly higher than in controls. There was no significant difference in signal intensity on T2-weighted images. The ADC did correlate with signal intensity. The distribution of the elevation of ADC may be the consequence of underlying pathological changes, such as neurofibrillary tangles or glial fibrillary tangles in the cortex. Our findings suggest that ADC measurement might be useful for demonstrating subtle neuropathological changes. (orig.)

  1. Apparent diffusion coefficient measurements in progressive supranuclear palsy

    Energy Technology Data Exchange (ETDEWEB)

    Ohshita, T.; Oka, M.; Imon, Y.; Yamaguchi, S.; Mimori, Y.; Nakamura, S. [Hiroshima Univ. (Japan). School of Medicine

    2000-09-01

    We measured the apparent diffusion coefficient (ADC), using diffusion-weighted imaging (DWI) and signal intensity on T2-weighted MRI in the cerebral white matter of patients with progressive supranuclear palsy (PSP) and age-matched normal subjects. In PSP, ADC in the prefrontal and precentral white matter was significantly higher than in controls. There was no significant difference in signal intensity on T2-weighted images. The ADC did correlate with signal intensity. The distribution of the elevation of ADC may be the consequence of underlying pathological changes, such as neurofibrillary tangles or glial fibrillary tangles in the cortex. Our findings suggest that ADC measurement might be useful for demonstrating subtle neuropathological changes. (orig.)

  2. Discrimination of paediatric brain tumours using apparent diffusion coefficient histograms

    Energy Technology Data Exchange (ETDEWEB)

    Bull, Jonathan G.; Clark, Christopher A. [UCL Institute of Child Health, Imaging and Biophysics Unit, London (United Kingdom); Saunders, Dawn E. [Great Ormond Street Hospital for Children NHS Trust, Department of Radiology, London (United Kingdom)

    2012-02-15

    To determine if histograms of apparent diffusion coefficients (ADC) can be used to differentiate paediatric brain tumours. Imaging of histologically confirmed tumours with pre-operative ADC maps were reviewed (54 cases, 32 male, mean age 6.1 years; range 0.1-15.8 years) comprising 6 groups. Whole tumour ADC histograms were calculated; normalised for volume. Stepwise logistic regression analysis was used to differentiate tumour types using histogram metrics, initially for all groups and then for specific subsets. All 6 groups (5 dysembryoplastic neuroectodermal tumours, 22 primitive neuroectodermal tumours (PNET), 5 ependymomas, 7 choroid plexus papillomas, 4 atypical teratoid rhabdoid tumours (ATRT) and 9 juvenile pilocytic astrocytomas (JPA)) were compared. 74% (40/54) were correctly classified using logistic regression of ADC histogram parameters. In the analysis of posterior fossa tumours, 80% of ependymomas, 100% of astrocytomas and 94% of PNET-medulloblastoma were classified correctly. All PNETs were discriminated from ATRTs (22 PNET and 4 supratentorial ATRTs) (100%). ADC histograms are useful in differentiating paediatric brain tumours, in particular, the common posterior fossa tumours of childhood. PNETs were differentiated from supratentorial ATRTs, in all cases, which has important implications in terms of clinical management. (orig.)

  3. ^3He Spin Pump

    Science.gov (United States)

    Yamaguchi, A.; Ishimoto, H.; Kojima, H.

    2009-03-01

    The superfluid component of ^3He A1 phase is spin-polarized. The process of forcing the superfluid component through a spin filtering structure, in a manner of mechano-magnetic effect, can be used to increase the spin polarization beyond the equilibrium under a given applied magnetic field. We have constructed a test cell in which a glass capillary array acts as the spin (and entropy) filter and an electrostatically actuated diaphragm forces the superfluid flow through it. Preliminary results show that a maximum relative increase of polarization by 50 % could be achieved. The maximum increase in polarization appears to be limited by the critical superfluid flow through the channels in the glass capillary array. The dependence of the observed effects on temperature, pressure and magnetic field will be presented.

  4. Hyperpolarised 3He MRI and 81mKr SPECT in chronic obstructive pulmonary disease

    International Nuclear Information System (INIS)

    During recent years, magnetic resonance imaging (MRI) using hyperpolarised (HP) 3He gas has emerged as a promising new method for the imaging of lung ventilation. However, systematic comparisons with nuclear medicine techniques have not yet been performed. The aim of this study was to compare ventilation imaging methods in 26 patients with chronic obstructive pulmonary disease (COPD) and nine lung healthy volunteers. HP 3He MRI, 81mKr single-photon emission computed tomography (SPECT), high-resolution computed tomography (HRCT) and pulmonary function tests were performed. The three scans were scored visually as percentage of non-ventilated/diseased lung, and a computer-based objective measure of the ventilated volume in HP 3He MRI and 81mKr SPECT and an emphysema index in HRCT were calculated. We found a good correlation between HP 3He MRI and 81mKr SPECT for both visual defect score (r=0.80, p81mKr SPECT (the score on HP 3He MRI was one-third less than that on 81mKr SPECT), but the difference was reduced after normalisation for different breathing depths (HP 3He MRI at total lung capacity; 81mKr SPECT at tidal breathing at functional residual capacity). HP 3He MRI provides detailed ventilation distribution images and defect scores are comparable on HP 3He MRI and 81mKr SPECT. Additionally, new insights into the regional pulmonary microstructure via the apparent diffusion coefficient measurements are provided by HP 3He MRI. HP 3He MRI is a promising new diagnostic tool for the assessment of ventilation distribution. (orig.)

  5. Tritium//sup 3/He dating of shallow groundwater

    Energy Technology Data Exchange (ETDEWEB)

    Schlosser, P.; Stute, M.; Doerr, H.; Sonntag, C.; Muennich, K.O.

    1988-08-01

    Combined tritium//sup 3/He data from three multi-level sampling wells (DFG 1, DFG 4, DFG 7) located at Liedern/Bocholt, West Germany, are presented and principles of the tritium//sup 3/He method in shallow groundwater studies are discussed. The /sup 3/He excess produced by radioactive decay of bomb tritium (released mainly between 1952 and 1963) is clearly reflected in the data. The tritiogenic /sup 3/He signal can be detected with a good resolution (signal/1sigma error: approx. = 350). The confinement of the tritiogenic /sup 3/He is estimated to approximately 77-85% at site DFG 4. For the bomb tritium peak the deviation of the tritium//sup 3/He age from the age determined by identifying the groundwater layer recharged between 1962 and 1965 is about 3 years (15%). The deviation can be explained by diffusive /sup 3/He loss across the groundwater table and by flow dispersion.

  6. Hyperpolarized 3He magnetic resonance imaging: Preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease

    International Nuclear Information System (INIS)

    Rationale and objectives: Emphysema and small airway obstruction are the pathological hallmarks of chronic obstructive pulmonary disease (COPD). The aim of this pilot study in a small group of chronic obstructive pulmonary disease (COPD) patients was to quantify hyperpolarized helium-3 (3He) magnetic resonance imaging (MRI) functional and structural measurements and to explore the potential role for 3He MRI in detecting the lung structural and functional COPD phenotypes. Materials and methods: We evaluated 20 ex-smokers with stage I (n = 1), stage II (n = 9) and stage III COPD (n = 10). All subjects underwent same-day plethysmography, spirometry, 1H MRI and hyperpolarized 3He MRI at 3.0 T. 3He ventilation defect percent (VDP) was generated from 3He static ventilation images and 1H thoracic images and the 3He apparent diffusion coefficient (ADC) was derived from diffusion-weighted MRI. Results: Based on the relative contribution of normalized ADC and VDP, there was evidence of a predominant 3He MRI measurement in seven patients (n = 3 mainly ventilation defects or VDP dominant (VD), n = 4 mainly increased ADC or ADC dominant (AD)). Analysis of variance (ANOVA) showed significantly lower ADC for subjects with predominantly elevated VDP (p = 0.02 compared to subjects with predominantly elevated ADC; p = 0.008 compared to mixed group) and significantly decreased VDP for subjects with predominantly elevated ADC (p = 0.003, compared to mixed group). Conclusion: In this small pilot study, a preliminary analysis shows the potential for 3He MRI to categorize or phenotype COPD ex-smokers, providing good evidence of feasibility for larger prospective studies.

  7. Diffusion-weighted imaging in breast cancer: relationship between apparent diffusion coefficient and tumour aggressiveness

    Energy Technology Data Exchange (ETDEWEB)

    Costantini, M.; Belli, P.; Rinaldi, P. [Department of Bio-Sciences and Radiological Imaging, Catholic University, Rome (Italy); Bufi, E., E-mail: reagandus@alice.i [Department of Bio-Sciences and Radiological Imaging, Catholic University, Rome (Italy); Giardina, G. [Department of Bio-Sciences and Radiological Imaging, Catholic University, Rome (Italy); Franceschini, G. [Department of Surgery, Catholic University, Rome (Italy); Petrone, G. [Department of Pathology, Catholic University, Rome (Italy); Bonomo, L. [Department of Bio-Sciences and Radiological Imaging, Catholic University, Rome (Italy)

    2010-12-15

    Aim: To assess the utility of diffusion-weighted imaging in diagnosing and characterizing breast malignancy. Materials and methods: From April 2006 to April 2009, all consecutive patients with breast cancer undergoing breast magnetic resonance imaging (MRI) and subsequent surgery in our hospital were enrolled in this study. MRI was performed using a 1.5 T MRI unit using a dedicated, bilateral, four-channel breast coil. The MRI protocol included a diffusion sequence acquired using b values of 0 and 1000 s/mm{sup 2}. For each malignant lesion the relationships between tumour grade and histology and the relative value of the apparent diffusion coefficient (ADC) were analysed. Results: There were 136 female patients with 162 lesions. Histology revealed 149 invasive carcinomas and 13 ductal carcinomas in situ. There were 34 grade 1, 61 grade 2, and 67 grade 3 lesions. The mean ADC value of all malignant lesions was 1.03 x 10{sup -3} mm{sup 2}/s. The mean ADC values for invasive and in situ carcinomas were 1.03 x 10{sup -3} mm{sup 2}/s and 1.05 x 10{sup -3} mm{sup 2}/s, respectively. The mean ADC values for grade 1, 2, and 3 tumours were 1.25 x 10{sup -3} mm{sup 2}/s, 1.02 x 10{sup -3} mm{sup 2}/s, and 0.92 x 10{sup -3} mm{sup 2}/s, respectively. A statistically significant (p < 0.001) inverse correlation was disclosed between the ADC value and the tumour grading. The mean ADC value of the 'less aggressive' group of disease (G1 and in situ lesions) was 1.19 x 10{sup -3} mm{sup 2}/s, whereas the mean ADC value of the 'more aggressive' group (G2-G3 invasive carcinomas) was 0.96 x 10{sup -3} mm{sup 2}/s (p < 0.001). Conclusion: The study confirms the usefulness of diffusion imaging in assessing the aggressiveness of breast tumours. ADC appears to be a promising parameter in the evaluation of the degree of malignancy of breast cancer tissue.

  8. Apparent diffusion coefficient of diffusion weighted MRI in endometrial carcinoma—Relationship with local invasiveness

    International Nuclear Information System (INIS)

    Objective: To evaluate the relationship between apparent diffusion coefficient (ADC) value and the local invasiveness of endometrial carcinoma. Methods and materials: The MR imaging of seventy-three patients with endometrial carcinoma proved by post-operative pathology and sixty-four patients with healthy uteri were retrospectively reviewed. All MR examinations included axial T2WI and T1WI, sagittal T2WI and diffusion-weighted sequences (b = 0 and b = 1000 s/mm2). Tumor size, mean ADC value (ADCm) and quartile ADC (ADCq) were acquired on post-processing workstation using voxel-analysis software. Differences between the ADC values among three layers of normal uterine body and endometrial carcinomas were compared by ANOVA test. Groups were divided according to pathologic type, histologic grade, depth of myometrial infiltration, presence of cervical invasion and lymphovascular space invasion, and lymph node metastasis. Tumor size and ADC values were compared and analyzed. Results: ADC values were different in three zones of uterine body (P −3 mm2/s] and highest in outer myometrium [(1.496 ± 0.196) × 10−3 mm2/s]. Mean ADC value of endometrial carcinomas [(1.011 ± 0.121) × 10−3 mm2/s] was lower than the normal uterine body. Quartile ADC and tumor size were greater in groups with more invasive pathologic factors (P < 0.05). Deep myometrial infiltration, cervical invasion, lymphovascular space invasion and lymph node metastasis were more common as quartile ADC values and tumor sizes increased. Conclusion: Mean ADC value was lower in endometrial carcinoma was lower than the normal uterus. Quartile ADC, representing the intra-tumor heterogeneity of water movement, had a profound relationship with invasiveness of endometrial carcinomas, while mean ADC value did not. ADC values may serve as a quantitative indicator to complement routine sequences.

  9. Association of early CT abnormalities, infarct size, and apparent diffusion coefficient reduction in acute ischemic stroke

    NARCIS (Netherlands)

    Somford, DM; Marks, MP; Thijs, VN; Tong, DC

    2004-01-01

    BACKGROUND AND PURPOSE: Diffusion-weighted (DW) imaging is more sensitive for early ischemia than CT, and apparent diffusion coefficient (ADC) mapping permits quantification of the severity of cytotoxic edema. We examined the relationship between early CT findings, ischemic lesion volume on DW image

  10. Diffusion-weighted imaging of normal fibroglandular breast tissue : influence of microperfusion and fat suppression technique on the apparent diffusion coefficient

    NARCIS (Netherlands)

    Baron, Paul; Dorrius, Monique D.; Kappert, Peter; Oudkerk, Matthijs; Sijens, Paul E.

    2010-01-01

    The influence of microperfusion and fat suppression technique on the apparent diffusion coefficient (ADC) values obtained with diffusion weighted imaging (DWI) of normal fibroglandular breast tissue was investigated. Seven volunteers (14 breasts) were scanned using diffusion weighting factors (b val

  11. Apparent diffusive motion of centrin foci in living cells: implications for diffusion-based motion in centriole duplication

    Science.gov (United States)

    Rafelski, Susanne M.; Keller, Lani C.; Alberts, Jonathan B.; Marshall, Wallace F.

    2011-04-01

    The degree to which diffusion contributes to positioning cellular structures is an open question. Here we investigate the question of whether diffusive motion of centrin granules would allow them to interact with the mother centriole. The role of centrin granules in centriole duplication remains unclear, but some proposed functions of these granules, for example, in providing pre-assembled centriole subunits, or by acting as unstable 'pre-centrioles' that need to be captured by the mother centriole (La Terra et al 2005 J. Cell Biol. 168 713-22), require the centrin foci to reach the mother. To test whether diffusive motion could permit such interactions in the necessary time scale, we measured the motion of centrin-containing foci in living human U2OS cells. We found that these centrin foci display apparently diffusive undirected motion. Using the apparent diffusion constant obtained from these measurements, we calculated the time scale required for diffusion to capture by the mother centrioles and found that it would greatly exceed the time available in the cell cycle. We conclude that mechanisms invoking centrin foci capture by the mother, whether as a pre-centriole or as a source of components to support later assembly, would require a form of directed motility of centrin foci that has not yet been observed.

  12. Apparent diffusive motion of centrin foci in living cells: implications for diffusion-based motion in centriole duplication

    International Nuclear Information System (INIS)

    The degree to which diffusion contributes to positioning cellular structures is an open question. Here we investigate the question of whether diffusive motion of centrin granules would allow them to interact with the mother centriole. The role of centrin granules in centriole duplication remains unclear, but some proposed functions of these granules, for example, in providing pre-assembled centriole subunits, or by acting as unstable 'pre-centrioles' that need to be captured by the mother centriole (La Terra et al 2005 J. Cell Biol. 168 713–22), require the centrin foci to reach the mother. To test whether diffusive motion could permit such interactions in the necessary time scale, we measured the motion of centrin-containing foci in living human U2OS cells. We found that these centrin foci display apparently diffusive undirected motion. Using the apparent diffusion constant obtained from these measurements, we calculated the time scale required for diffusion to capture by the mother centrioles and found that it would greatly exceed the time available in the cell cycle. We conclude that mechanisms invoking centrin foci capture by the mother, whether as a pre-centriole or as a source of components to support later assembly, would require a form of directed motility of centrin foci that has not yet been observed

  13. A multipurpose 3He refrigerator

    Science.gov (United States)

    Pizzo, L.; Dall'Oglio, G.; Martinis, L.; Sabbatini, L.

    2006-10-01

    We introduce a mini 3He refrigerator, operating at ˜300 mK starting from 4.2 K without pumping on the main 4He bath. The innovative idea is that the present one is suitable for a very fast operation; for its use, it is sufficient a storage 4He Dewar. In this way we drastically reduce the time required to cool it down, because there is no need for a classic cryostat. This prototype is particularly aimed for all those operations in which it is necessary to test a large number of samples that do not require long duration measurements at low temperature.

  14. Role of magnetic resonance diffusion imaging and apparent diffusion coefficient values in the evaluation of spinal tuberculosis in Indian patients

    International Nuclear Information System (INIS)

    To define a range of apparent diffusion coefficient values in spinal tuberculosis and to evaluate the sensitivity of diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient values in patients of spinal tuberculosis. This study was conducted over a period of 20 months and included 110 patients with a total of 230 vertebral bodies. The study was performed in two parts. The first part included all patients of known tuberculosis and patients with classical features of tuberculosis. The second part included patients with spinal pathology of indeterminate etiology. All the patients underwent a routine MRI examination along with diffusion sequences. The apparent diffusion coefficient (ADC) values were calculated from all the involved vertebral bodies. The mean ADC value of affected vertebrae in first part of the study was found to be 1.4 ± 0.20 × 10−3 mm2/s. This ADC value was then applied to patients in the second part of study in order to determine its ability in predicting tuberculosis. This range of ADC values was significantly different from the mean ADC values of normal vertebrae and those with metastatic involvement. However, there was an overlap of ADC values in a few tuberculous vertebrae with the ADC values in metastatic vertebrae. We found that DW-MRI and ADC values may help in the differentiation of spinal tuberculosis from other lesions of similar appearance. However, an overlap of ADC values was noted with those of metastatic vertebrae. Therefore diffusion imaging and ADC values must always be interpreted in association with clinical history and routine MRI findings and not in isolation

  15. The apparent diffusion coefficient does not reflect cytotoxic edema on the uninjured side after traumatic brain injury

    OpenAIRE

    Lu, Hong; Lei, Xiaoyan

    2014-01-01

    After traumatic brain injury, vasogenic and cytotoxic edema appear sequentially on the involved side. Neuroimaging investigations of edema on the injured side have employed apparent diffusion coefficient measurements in diffusion tensor imaging. We investigated the changes occurring on the injured and uninjured sides using diffusion tensor imaging/apparent diffusion coefficient and histological samples in rats. We found that, on the injured side, that vasogenic edema appeared at 1 hour and in...

  16. A comparison of concentration measurement techniques for the estimation of the apparent mass diffusion coefficient

    Directory of Open Access Journals (Sweden)

    L.M. Pereira

    2001-09-01

    Full Text Available In this article we compare two different techniques to measure the concentration of saline solutions for the identification of the apparent mass diffusion coefficient in soils saturated with distilled water. They are the radiation measurement technique and the electrical conductivity measurement technique. These techniques are compared in terms of measured quantities, sensitivity coefficients with respect to unknown parameters and the determinant of the information matrix. The apparent mass diffusion coefficient is estimated by utilizing simulated measurements containing random errors. The Levenberg-Marquardt method of minimization of the least-squares norm is used as the parameter estimation procedure. The effects of the volume of saline solution injected into the column devised for the experiments on the accuracy of the estimated parameters are also addressed in this article.

  17. Apparent diffusion coefficient ratio correlates significantly with prostate cancer gleason score at final pathology

    DEFF Research Database (Denmark)

    Boesen, Lars; Chabanova, Elizaveta; Løgager, Vibeke;

    2015-01-01

    PURPOSE: To evaluate the correlation between apparent diffusion coefficient measurements (ADCtumor and ADCratio ) and the Gleason score from radical prostatectomy specimens. MATERIALS AND METHODS: Seventy-one patients with clinically localized prostate cancer scheduled for radical prostatectomy...... were prospectively enrolled. Multiparametric magnetic resonance imaging (MRI) was performed prior to prostatectomy and mean ADC values from both cancerous (ADCtumor ) and benign (ADCbenign ) tissue were measured to calculate the ADCratio (ADCtumor divided by ADCbenign ). The ADC measurements were...

  18. Hyperpolarized {sup 3}He magnetic resonance imaging: Preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease

    Energy Technology Data Exchange (ETDEWEB)

    Mathew, Lindsay, E-mail: lmathew@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Department of Medical Biophysics, University of Western Ontario, London (Canada); Kirby, Miranda, E-mail: mkirby@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Department of Medical Biophysics, University of Western Ontario, London (Canada); Etemad-Rezai, Roya, E-mail: Roya.EtemadRezai@lhsc.on.ca [Department of Medical Imaging, University of Western Ontario (Canada); Wheatley, Andrew, E-mail: awheat@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); McCormack, David G., E-mail: David.McCormack@lhsc.on.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Division of Respirology, Department of Medicine, University of Western Ontario, London (Canada); Lawson Health Research Institute, London (Canada); Parraga, Grace, E-mail: gep@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Department of Medical Biophysics, University of Western Ontario, London (Canada); Department of Medical Imaging, University of Western Ontario (Canada); Lawson Health Research Institute, London (Canada)

    2011-07-15

    Rationale and objectives: Emphysema and small airway obstruction are the pathological hallmarks of chronic obstructive pulmonary disease (COPD). The aim of this pilot study in a small group of chronic obstructive pulmonary disease (COPD) patients was to quantify hyperpolarized helium-3 ({sup 3}He) magnetic resonance imaging (MRI) functional and structural measurements and to explore the potential role for {sup 3}He MRI in detecting the lung structural and functional COPD phenotypes. Materials and methods: We evaluated 20 ex-smokers with stage I (n = 1), stage II (n = 9) and stage III COPD (n = 10). All subjects underwent same-day plethysmography, spirometry, {sup 1}H MRI and hyperpolarized {sup 3}He MRI at 3.0 T. {sup 3}He ventilation defect percent (VDP) was generated from {sup 3}He static ventilation images and {sup 1}H thoracic images and the {sup 3}He apparent diffusion coefficient (ADC) was derived from diffusion-weighted MRI. Results: Based on the relative contribution of normalized ADC and VDP, there was evidence of a predominant {sup 3}He MRI measurement in seven patients (n = 3 mainly ventilation defects or VDP dominant (VD), n = 4 mainly increased ADC or ADC dominant (AD)). Analysis of variance (ANOVA) showed significantly lower ADC for subjects with predominantly elevated VDP (p = 0.02 compared to subjects with predominantly elevated ADC; p = 0.008 compared to mixed group) and significantly decreased VDP for subjects with predominantly elevated ADC (p = 0.003, compared to mixed group). Conclusion: In this small pilot study, a preliminary analysis shows the potential for {sup 3}He MRI to categorize or phenotype COPD ex-smokers, providing good evidence of feasibility for larger prospective studies.

  19. Emphysema Quantification in Inflation-Fixed Lungs Using Low-Dose Computed Tomography and 3He Magnetic Resonance Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Gierada, David S.; Woods, Jason C.; Jacob, Rick E.; Bierhals, Andrew J.; Choong, Cliff K.; Bartel, Seth T.; Chang, Yulin V.; Das, Nitin A.; Hong, Cheng; Lutey, Barbara; Ritter, Jon H.; Pilgram, Thomas K.; Cooper, Joel D.; Patterson, G Alexander; Battafarano, Richard J.; Meyers, Bryan F.; Yablonskiy, Dmitriy A.; Conradi, Mark S.

    2010-09-02

    Abstract: Objective: To evaluate the use of inflation-fixed lung tissue for emphysema quantification with CT and 3He MR diffusion imaging. Methods: Fourteen subjects representing a range of chronic obstructive pulmonary disease severity who underwent complete or lobar lung resection were studied. CT measurements of lung attenuation and MR measurements of the hyperpolarized 3He apparent diffusion coefficient (ADC) in resected specimens fixed in inflation with heated formalin vapor were compared with measurements obtained before fixation. Results: The mean CT emphysema index was 56% ± 17% before and 58% ± 19% after fixation (P=0.77;R=0.76). Index differences correlated with differences in lung volume (R2=0.47). The mean 3He ADC was 0.40 ± 0.15 cm2/sec before and 0.39 ± 0.14 cm2/sec after fixation (P=0.03, R=0.98). The CT emphysema index and the 3He ADC were correlated before (R=0.89) and after fixation (R=0.79). Conclusion: Concordance of CT and 3He MR imaging measurements in unfixed and inflation-fixed lungs supports the use of inflation-fixed lungs for quantitative imaging studies in emphysema.

  20. Models and Applications of in Vivo Lung Morphometry with Hyperpolarized 3He MRI in a Mild COPD Population

    Science.gov (United States)

    Quirk, James D.; Sukstanskii, Alexander L.; Gierada, David S.; Woods, Jason C.; Conradi, Mark S.; Yablonskiy, Dmitriy A.

    2008-12-01

    Hyperpolarized 3He diffusion MRI is increasingly used to non-invasively quantify local alveolar structure changes, such as those from Chronic Obstructive Pulmonary Disease (COPD). Previously, we described an in vivo lung morphometry technique that decouples the helium apparent diffusion coefficient (ADC) into components oriented along the longitudinal (DL) and transverse (DT) axes of the acinar airways. Herein, we discuss our recent expansion of this theory, which relates the anisotropy of the MRI diffusion signal to the geometrical parameters of the acinar airways. We demonstrate the utility of this model in human studies and compare the measured airway radii with prior ex vivo experiments.

  1. The Panofsky ratio in 3He

    International Nuclear Information System (INIS)

    The branching ratios have been measured for γ-ray channels produced by π- stopping in liquid 3He. The results for the Panofsky ratio are P3 = ω(π-3He → π0t)/ω(π-3He → γt) = 2.83±0.07, and for the ratio of the radiative breakup channels, B3 = ω(π-3He → γnd+γnnp)/ω(π-3He → γt) = 1.35±0.11. (orig.)

  2. The Panofsky ratio in 3He

    Science.gov (United States)

    Corriveau, F.; Hasinoff, M. D.; Measday, D. F.; Poutissou, J.-M.; Salomon, M.

    1987-11-01

    The branching ratios have been measured for γ-ray channels produced by π- stopping in liquid 3He. The results for the Panofsky ratio are P3 = ω( π-3He → π0t)/ ω( π-3He → γt) = 2.83 ± 0.07, and for the ratio of the radiative breakup channels, B3 = ω)( π-3He → γnd + γnnp)/ ω( π-3He → γt) = 1.35 ±0.11.

  3. Apparent Diffusion Coefficient Maps of Pediatric Mass Lesions with Free-Breathing Diffusion-Weighted Magnetic Resonance: Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, Oe.E.; Sebire, N.J. [Great Ormond Street Hospital for Children NHS Trust, London (United Kingdom). Radiology and Histopathology Depts.

    2006-03-15

    Purpose: To assess the technical feasibility of apparent diffusion coefficient (ADC) mapping based on free-breathing diffusion-weighted magnetic resonance (DW-MR) outside the CNS in children. Material and Methods: Twelve children with mass lesions of varied histopathology were scanned with short-tau inversion recovery (STIR), contrast-enhanced T1-weighted (CE-T1W), and diffusion-weighted (b = 0, 500 and 1,000 s/mm{sup 2}) sequences. ADC maps were calculated. Lesion-to-background signal intensity ratios were measured and compared between STIR/CE-T1W/ADC overall (Friedman test) and between viable embryonal tumors and other lesions (Kruskal-Wallis test). Results: ADC maps clearly depicted all lesions. Lesion-to-background signal intensity ratios of STIR (median 3.7), CE-T1W (median 1.4), and ADC (median 1.6) showed no overall difference (chi-square = 3.846; P = 0.146), and there was no difference between viable embryonal tumors and other lesions within STIR/CE-T1W/ADC (chi-square 1.118/0.669/<0.001; P = 0.290/0.414/1.000, respectively). Conclusion: ADC mapping is feasible in free-breathing imaging of pediatric mass lesions outside the CNS using standard clinical equipment. Keywords: Diffusion-weighted magnetic resonance imaging; infants and children; neoplasms.

  4. A new in-situ method to determine the apparent gas diffusion coefficient of soils

    Science.gov (United States)

    Laemmel, Thomas; Paulus, Sinikka; Schack-Kirchner, Helmer; Maier, Martin

    2015-04-01

    Soil aeration is an important factor for the biological activity in the soil and soil respiration. Generally, gas exchange between soil and atmosphere is assumed to be governed by diffusion and Fick's Law is used to describe the fluxes in the soil. The "apparent soil gas diffusion coefficient" represents the proportional factor between the flux and the gas concentration gradient in the soil and reflects the ability of the soil to "transport passively" gases through the soil. One common way to determine this coefficient is to take core samples in the field and determine it in the lab. Unfortunately this method is destructive and needs laborious field work and can only reflect a small fraction of the whole soil. As a consequence insecurity about the resulting effective diffusivity on the profile scale must remain. We developed a new in-situ method using new gas sampling device, tracer gas and inverse soil gas modelling. The gas sampling device contains several sampling depths and can be easily installed into vertical holes of an auger, which allows for fast installation of the system. At the lower end of the device inert tracer gas is injected continuously. The tracer gas diffuses into the surrounding soil. The resulting distribution of the tracer gas concentrations is used to deduce the diffusivity profile of the soil. For Finite Element Modeling of the gas sampling device/soil system the program COMSOL is used. We will present the results of a field campaign comparing the new in-situ method with lab measurements on soil cores. The new sampling pole has several interesting advantages: it can be used in-situ and over a long time; so it allows following modifications of diffusion coefficients in interaction with rain but also vegetation cycle and wind.

  5. Apparent diffusion coefficient parametric response mapping MRI for follow-up of glioblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Ra Gyoung [Catholic Kwandong University International St. Mary' s Hospital, Catholic Kwandong University College of Medicine, Department of Radiology, Seo-gu, Incheon (Korea, Republic of); Kim, Ho Sung; Hong, Gil Sun; Kim, Sang Joon [Asan Medical Center, University of Ulsan College of Medicine, Department of Radiology and Research Institute of Radiology, Songpa-Gu, Seoul (Korea, Republic of); Kim, Dae Yoon [Bundang Jesaeng Hospital, Department of Radiology, Seongnam-si, Gyeonggi-do (Korea, Republic of)

    2016-04-15

    To determine the diagnostic superiority of parametric response mapping of apparent diffusion coefficient (ADCPR) for predicting glioblastoma treatment response, compared to single time point measurement. Fifty post-treatment glioblastoma patients were enrolled. ADCPR was calculated from serial apparent diffusion coefficient (ADC) maps acquired before and at the time of first detection of an enlarged contrast-enhancing lesion on voxel-by-voxel basis. The percentage-decrease in ADCPR and tenth percentile histogram cutoff value of ADC (ADC10) were compared at subsequent 3-month and 1-year follow-ups. The percentage-decrease in ADCPR was significantly higher in the progression group (mean = 33.2-38.3 %) than in the stable-response group (mean = 9.7 %) at 3 months follow-up (corrected p < 0.001 for both readers). ADCPR significantly improved area under the receiver operating characteristic curve from 0.67 to 0.88 (corrected p = 0.037) and from 0.70 to 0.92 (corrected p = 0.020) for both readers, respectively, compared to ADC10 at 3-month follow-up, but did not significantly improve at 1-year follow-up. The inter-reader agreement was higher for ADCPR than ADC10 (intraclass correlation coefficient, 0.93 versus 0.86). Voxel-based ADCPR appears to be a superior imaging biomarker than ADC, particularly for predicting early tumour progression in patients with glioblastoma. (orig.)

  6. Functional evaluation of hydronephrosis by diffusion-weighted MR imaging: Relationship between apparent diffusion coefficient and split glomerular filtration rate

    Energy Technology Data Exchange (ETDEWEB)

    Toyoshima, S.; Noguchi, K.; Seto, H.; Shimizu, M.; Watanabe, N. [Toyama Medical and Pharmaceutical Univ. (Japan). Dept. of Radiology

    2000-11-01

    To determine the relationship between apparent diffusion coefficient (ADC) values measured by diffusion-weighted MR imaging and split renal function determined by renal scintigraphy in patients with hydronephrosis. Material and Methods: Diffusion-weighted imaging on a 1.5 T MR unit and renal scintigraphy were performed in 36 patients with hydronephrosis (45 hydronephrotic kidneys, 21 non-hydronephrotic kidneys). ADC values of the individual kidneys were measured by diffusion-weighted MR imaging. Split renal function (glomerular filtration rate (GFR)) was determined by renal scintigraphy using {sup 99m}Tc-DTPA. The relationship between ADC values and split GFR was examined in 66 kidneys. The hydronephrotic kidneys were further classified into three groups (severe renal dysfunction, GFR <10 ml/min, n=7; moderate renal dysfunction, GFR 10-25 ml/min, n=10; normal renal function, GFR >25 ml/min, n=28), and mean values for ADCs were calculated. Results: In hydronephrotic kidneys, there was a moderate positive correlation between ADC values and split GFR (R2=0.56). On the other hand, in non-hydronephrotic kidneys, poor correlation between ADC values and split GFR was observed (R2=0.08). The mean values for ADCs of the dysfunctioning hydronephrotic kidneys (severe renal dysfunction, 1.32x10{sup -3}{+-}0.18x10{sup -3} mm{sup 2}/s; moderate renal dysfunction, 1.38x10{sup -3}{+-}0.10x10{sup -3} mm2/s) were significantly lower than that of the normal functioning hydronephrotic kidneys (1.63x10{sup -3}{+-}0.12{+-}10{sup -3} mm{sup 2}/s). Conclusion: These results indicated that measurement of ADC values by diffusion-weighted MR imaging has a potential value in the evaluation of the functional status of hydronephrotic kidneys.

  7. Correlation between 3 T apparent diffusion coefficient values and grading of invasive breast carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Cipolla, Valentina, E-mail: valentina.cipolla@yahoo.it [Department of Radiological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy); Santucci, Domiziana; Guerrieri, Daniele; Drudi, Francesco Maria [Department of Radiological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy); Meggiorini, Maria Letizia [Department of Gynaecological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy); Felice, Carlo de [Department of Radiological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy)

    2014-12-15

    Highlights: • Apparent diffusion coefficient is a quantitative parameter which reflects molecular water movement. • Grading is an independent prognostic factor which correlates with other histopathological features. • Apparent diffusion coefficient values were significantly different between G1 and G3 classes. - Abstract: Purpose: The aim of this study was to evaluate whether the apparent diffusion coefficient (ADC) provided by 3.0 T (3 T) magnetic resonance diffusion-weighted imaging (DWI) varied according to the grading of invasive breast carcinoma. Materials and methods: A total of 92 patients with 96 invasive breast cancer lesions were enrolled; all had undergone 3 T magnetic resonance imaging (MRI) for local staging. All lesions were confirmed by histological analysis, and tumor grade was established according to the Nottingham Grading System (NGS). MRI included both dynamic contrast-enhanced and DWI sequences, and ADC value was calculated for each lesion. ADC values were compared with NGS classification using the Mann–Whitney U and the Kruskal–Wallis H tests. Grading was considered as a comprehensive prognostic factor, and Rho Spearman test was performed to determine correlation between grading and tumor size, hormonal receptor status, HER2 expression and Ki67 index. Pearson's Chi square test was carried out to compare grading with the other prognostic factors. Results: ADC values were significantly higher in G1 than in G3 tumors. No significant difference was observed when G1 and G3 were compared with G2. Tumor size, hormonal receptor status, HER2 expression and Ki67 index correlated significantly with grading but there was a significant difference only between G1 and G3 related to the ER and PR status, HER2 expression and Ki67 index. There was no statistically significant difference in lesion size between the two groups. Conclusion: ADC values obtained on 3 T DWI correlated with low-grade (G1) and high-grade (G3) invasive breast carcinoma. 3

  8. Apparent diffusion coefficient and fractional anisotropy of newly diagnosed grade II gliomas†

    Science.gov (United States)

    Khayal, Inas S.; McKnight, Tracy R.; McGue, Colleen; Vandenberg, Scott; Lamborn, Kathleen R.; Chang, Susan M.; Cha, Soonmee; Nelson, Sarah J.

    2013-01-01

    Distinguishing between low-grade oligodendrogliomas (ODs) and astrocytomas (AC) is of interest for defining prognosis and stratifying patients to specific treatment regimens. The purpose of this study was to determine if the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) from diffusion imaging can help to differentiate between newly diagnosed grade II OD and AC subtypes and to evaluate the ADC and FA values for the mixed population of oligoastrocytomas (OA). Fifty-three patients with newly diagnosed grade II gliomas were studied using a 1.5T whole body scanner (23 ODs, 16 ACs, and 14 OAs). The imaging protocol included post-gadolinium T1-weighted images, T2-weighted images, and either three and/or six directional diffusion imaging sequence with b = 1000 s/mm2. Diffusion-weighted images were analyzed using in-house software to calculate maps of ADC and for six directional acquisitions, FA. The intensity values were normalized by values from normal appearing white matter (NAWM) to generate maps of normalized apparent diffusion coefficient (nADC) and normalized fractional anisotropy (nFA). The hyperintense region in the T2 weighted image was defined as the T2All region. A Mann–Whitney rank-sum test was performed on the 25th, median, and 75th nADC and nFA among the three subtypes. Logistic regression was performed to determine how well the nADC and nFA predict subtype. Lesions diagnosed as being OD had significantly lower nADC and significantly higher nFA, compared to AC. The nADC and nFA values individually classified the data with an accuracy of 87%. Combining the two did not enhance the classification. The patients with OA had nADC and nFA values between those of OD and AC. This suggests that ADC and FA may be helpful in directing tissue sampling to the most appropriate regions for taking biopsies in order to make a definitive diagnosis. PMID:19125391

  9. The apparent diffusion coefficient does not reflect cytotoxic edema on the uninjured side after traumatic brain injury

    Institute of Scientific and Technical Information of China (English)

    Hong Lu; Xiaoyan Lei

    2014-01-01

    After traumatic brain injury, vasogenic and cytotoxic edema appear sequentially on the in-volved side. Neuroimaging investigations of edema on the injured side have employed apparent diffusion coefficient measurements in diffusion tensor imaging. We investigated the changes occurring on the injured and uninjured sides using diffusion tensor imaging/apparent diffusion coefficient and histological samples in rats. We found that, on the injured side, that vasogen-ic edema appeared at 1 hour and intracellular edema appeared at 3 hours. Mixed edema was observed at 6 hours, worsening until 12-24 hours post-injury. Simultaneously, microglial cells proliferated at the trauma site. Apparent diffusion coefficient values increased at 1 hour, decreased at 6 hours, and increased at 12 hours. The uninjured side showed no significant pathological change at 1 hour after injury. Cytotoxic edema appeared at 3 hours, and vasogen-ic edema was visible at 6 hours. Cytotoxic edema persisted, but vasogenic edema tended to decrease after 12-24 hours. Despite this complex edema pattern on the uninjured side with associated pathologic changes, no significant change in apparent diffusion coefficient values was detected over the first 24 hours. Apparent diffusion coefficient values accurately detected the changes on the injured side, but did not detect the changes on the uninjured side, giving a false-negative result.

  10. Apparent diffusion coefficient histogram analysis of neonatal hypoxic-ischemic encephalopathy

    Energy Technology Data Exchange (ETDEWEB)

    Cauley, Keith A. [University of Massachusetts Medical School, Department of Radiology, Worcester, MA (United States); New York Presbyterian Hospital, Columbia University Medical Center, Department of Radiology, New York, NY (United States); Filippi, Christopher G. [New York Presbyterian Hospital, Columbia University Medical Center, Department of Radiology, New York, NY (United States)

    2014-06-15

    Diffusion-weighted imaging is a valuable tool in the assessment of the neonatal brain, and changes in diffusion are seen in normal development as well as in pathological states such as hypoxic-ischemic encephalopathy (HIE). Various methods of quantitative assessment of diffusion values have been reported. Global ischemic injury occurring during the time of rapid developmental changes in brain myelination can complicate the imaging diagnosis of neonatal HIE. To compare a quantitative method of histographic analysis of brain apparent coefficient (ADC) maps to the qualitative interpretation of routine brain MR imaging studies. We correlate changes in diffusion values with gestational age in radiographically normal neonates, and we investigate the sensitivity of the method as a quantitative measure of hypoxic-ischemic encephalopathy. We reviewed all brain MRI studies from the neonatal intensive care unit (NICU) at our university medical center over a 4-year period to identify cases that were radiographically normal (23 cases) and those with diffuse, global hypoxic-ischemic encephalopathy (12 cases). We histographically displayed ADC values of a single brain slice at the level of the basal ganglia and correlated peak (s-sD{sub av}) and lowest histogram values (s-sD{sub lowest}) with gestational age. Normative s-sD{sub av} values correlated significantly with gestational age and declined linearly through the neonatal period (r {sup 2} = 0.477, P < 0.01). Six of 12 cases of known HIE demonstrated significantly lower s-sD{sub av} and s-sD{sub lowest} ADC values than were reflected in the normative distribution; several cases of HIE fell within a 95% confidence interval for normative studies, and one case demonstrated higher-than-normal s-sD{sub av}. Single-slice histographic display of ADC values is a rapid and clinically feasible method of quantitative analysis of diffusion. In this study normative values derived from consecutive neonates without radiographic evidence of

  11. Optimal Experiment Design for Monoexponential Model Fitting: Application to Apparent Diffusion Coefficient Imaging

    Science.gov (United States)

    Alipoor, Mohammad; Maier, Stephan E.; Gu, Irene Yu-Hua; Mehnert, Andrew; Kahl, Fredrik

    2015-01-01

    The monoexponential model is widely used in quantitative biomedical imaging. Notable applications include apparent diffusion coefficient (ADC) imaging and pharmacokinetics. The application of ADC imaging to the detection of malignant tissue has in turn prompted several studies concerning optimal experiment design for monoexponential model fitting. In this paper, we propose a new experiment design method that is based on minimizing the determinant of the covariance matrix of the estimated parameters (D-optimal design). In contrast to previous methods, D-optimal design is independent of the imaged quantities. Applying this method to ADC imaging, we demonstrate its steady performance for the whole range of input variables (imaged parameters, number of measurements, and range of b-values). Using Monte Carlo simulations we show that the D-optimal design outperforms existing experiment design methods in terms of accuracy and precision of the estimated parameters. PMID:26839880

  12. LUNG DIFFUSION CAPACITY CAN PREDICT MAXIMAL EXERCISE IN APPARENTLY HEALTHY HEAVY SMOKERS

    Directory of Open Access Journals (Sweden)

    Alfredo Chetta

    2008-06-01

    Full Text Available Chronic exposure to tobacco smoking may damage lung and heart function. The aim of this study was to assess maximal exercise capacity and its relationship with lung function in apparently healthy smokers. We recruited 15 heavy smokers (age 47 years ± 7, BMI 25 kg/m2 ± 3, pack/years 32 ± 9 without any cardiovascular or pulmonary signs and symptoms. Fifteen healthy non smoking subjects were enrolled as a control group. All subjects underwent pulmonary function tests, electrocardiograms at rest and graded cycle exercise tests. In smokers and controls, resting lung and cardiac function parameters were in the normal range, apart from diffusing lung capacity (TLCO values which were significantly lower in smokers (p < 0.05. As compared to controls, smokers presented lower maximal exercise capacity with lower values at peak of exercise of oxygen uptake (peak VO2, workload, oxygen uptake/watt ratio and oxygen pulse (p < 0.05 and higher dyspnoea perception (p < 0.05. Moreover, peak VO2, maximal workload and oxygen pulse at peak exercise were related to and predicted by TLCO (p < 0. 05. Our study confirms that maximal exercise capacity is reduced in apparently healthy heavy smokers, and shows that TLCO explains some of the variance in maximal exercise

  13. Tritiogenic 3He in shallow groundwater

    Science.gov (United States)

    Schlosser, Peter; Stute, Martin; Sonntag, Christian; Otto Münnich, Karl

    1989-09-01

    Tritium, helium isotope and neon data from a multi-level sampling well (DFG 7) at Liedern/Bocholt (West Germany) are presented and discussed. The presence of a radiogenic helium component leads to 3He/ 4He ratios below that of atmospheric helium ( minimumδ 3He values≈ -60% ) below about 20 m depth. The 3He profile can be corrected for the nucleogenic 3He component using the neon measurements. Based on the "Vogel" model of a shallow aquifer the tritium/ 3He distributions are simulated for the years 1987, 2000 and 2025. The model results show that under favourable conditions the tritiogenic 3He peak will be detectable in shallow aquifers for at least the next 4 decades. The influence of the vertical flow velocity and the transversal dispersion coefficient on simulated distributions are estimated. 3He confinement is calculated as a function of the vertical flow velocity and the transversal dispersion coefficient. There is a critical value of the vertical flow velocity (about 0.25-0.5 m/year) below which the 3He loss increases rapidly to high values.

  14. Tritiogenic sup 3 He in shallow groundwater

    Energy Technology Data Exchange (ETDEWEB)

    Schlosser, P.; Stute, M.; Sonntag, C.; Muennich, K.O. (Heidelberg Univ. (Germany, F.R.). Inst. fuer Umweltphysik)

    1989-09-01

    Tritium, helium isotope and neon data from a multi-level sampling well (DFG 7) at Liedern/Bocholt (West Germany) are presented and discussed. The presence of a radiogenic helium component leads to {sup 3}He/{sup 4}He ratios below that of atmospheric helium (minimum {delta}{sup 3}He values {approx equal} -60%) below about 20 m depth. The {sup 3}He profile can be corrected for the nucleogenic {sup 3}He component using the neon measurements. Based on the ''Vogel'' model of a shallow aquifer the tritium/{sup 3}He distributions are simulated for the years 1987, 2000 and 2025. The model results show that under favourable conditions the tritiogenic {sup 3}He peak will be detectable in shallow aquifers for at least the next 4 decades. The influence of the vertical flow velocity and the transversal dispersion coefficient on simulated distributions are estimated. {sup 3}He confinement is calculated as a function of the vertical flow velocity and the transversal dispersion coefficient. There is a critical value of the vertical flow velocity (about 0.25-0.5 m/year) below which the {sup 3}He loss increases rapidly to high values. (orig.).

  15. Apparent diffusion coefficient in cervical cancer of the uterus: comparison with the normal uterine cervix

    Energy Technology Data Exchange (ETDEWEB)

    Naganawa, Shinji; Sato, Chiho; Ishigaki, Takeo [Nagoya University School of Medicine, Department of Radiology, Nagoya (Japan); Kumada, Hisashi; Miura, Shunichi [Toyohashi Municipal hospital, Department of Radiology, Toyohashi, Aich (Japan); Takizawa, Osamu [Siemens-Asahi Medical Technologies Ltd, Tokyo (Japan)

    2005-01-01

    A relation between apparent diffusion coefficient (ADC) values and tumor cellular density has been reported. The purpose of this study was to measure the ADC values of cervical cancers in the uterus and compare them with those of normal cervical tissues, and to test whether ADC could differentiate between normal and malignant cervical tissues in the uterus. Twelve consecutive female patients with cervical cancer of the uterus and ten female patients with other pelvic abnormalities were included in this study. ADC was measured at 1.5 T with b-factors of 0, 300 and 600 s/mm{sup 2} using single-shot echo-planar diffusion-weighted imaging and a parallel imaging technique. The mean ADC value of cervical cancer lesions was 1.09{+-}0.20 x 10{sup -3} mm{sup 2}/s, and that of normal cervix tissue was 1.79{+-}0.24 x 10{sup -3} mm{sup 2}/s (P<0.0001). In nine patients treated by chemotherapy and/or radiation therapy, the mean ADC value of the cervical cancer lesion increased significantly after therapy (P<0.001). The present study showed, with a small number of patients, that ADC measurement has a potential ability to differentiate between normal and cancerous tissue in the uterine cervix. Further study is necessary to determine the accuracy of ADC measurement in monitoring the treatment response. (orig.)

  16. Regional apparent diffusion coefficient values in 3rd trimester fetal brain

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, Chen [Tel Aviv University, Department of Radiology, Sheba Medical Center, Tel Hashomer (affiliated to the Sackler School of Medicine), Tel Aviv (Israel); Sheba Medical Center, Diagnostic Imaging, 52621, Tel Hashomer (Israel); Weisz, Boaz; Lipitz, Shlomo; Katorza, Eldad [Tel Aviv University, Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer (affiliated to the Sackler School of Medicine), Tel Aviv (Israel); Yaniv, Gal; Bergman, Dafi [Tel Aviv University, Department of Radiology, Sheba Medical Center, Tel Hashomer (affiliated to the Sackler School of Medicine), Tel Aviv (Israel); Biegon, Anat [Stony Brook University School of Medicine, Department of Neurology, Stony Brook, NY (United States)

    2014-07-15

    Apparent diffusion coefficient (ADC) values in the developing fetus can be used in the diagnosis and prognosis of prenatal brain pathologies. To this end, we measured regional ADC in a relatively large cohort of normal fetal brains in utero. Diffusion-weighted imaging (DWI) was performed in 48 non-sedated 3rd trimester fetuses with normal structural MR imaging results. ADC was measured in white matter (frontal, parietal, temporal, and occipital lobes), basal ganglia, thalamus, pons, and cerebellum. Regional ADC values were compared by one-way ANOVA with gestational age as covariate. Regression analysis was used to examine gestational age-related changes in regional ADC. Four other cases of CMV infection were also examined. Median gestational age was 32 weeks (range, 26-33 weeks). There was a highly significant effect of region on ADC, whereby ADC values were highest in white matter, with significantly lower values in basal ganglia and cerebellum and the lowest values in thalamus and pons. ADC did not significantly change with gestational age in any of the regions tested. In the four cases with fetal CMV infection, ADC value was associated with a global decrease. ADC values in normal fetal brain are relatively stable during the third trimester, show consistent regional variation, and can make an important contribution to the early diagnosis and possibly prognosis of fetal brain pathologies. (orig.)

  17. Relationship of apparent diffusion coefficient to survival for patients with unresectable primary hepatocellular carcinoma after chemoembolization

    International Nuclear Information System (INIS)

    Objectives: to evaluate the prognostic value of apparent diffusion coefficient (ADC) values from MR diffusion-weighted imaging of unresectable hepatocellular carcinoma after chemoembolization. Methods: our study was proved by our institute and informed consent was obtained from all patients before commencement of the study. Twenty-three patients with unresectable hepatocellular carcinoma were scanned immediately before and after chemoembolization within 24 h using conventional anatomical MR imaging and diffusion-weighted imaging, from which ADC values in the lesions were measured. The changes in ADC values after chemoembolization were calculated. The relationship between the lesion ADC and the survival time was analyzed by correlation analysis. The overall cumulative survival was analyzed by the Kaplan–Meier method, and survival curves were compared by the log-rank test. Results: the mean overall survival period was (25.0 ± 8.7) months. The pre-chemoembolization lesion ADC value was (1.36 ± 0.249) ×10−3 mm2/s; the change in ADC values post-chemoembolization was (0.377 ± 0.332) ×10−3 mm2/s. There were significant linear regression relation between the survival time and pre-chemoembolization lesion ADC values (r = −0.698, P 2 = 7.339, P = 0.007) or the changes in ADC value post-chemoembolization (χ2 = 9.820, P = 0.002) significantly influenced the overall cumulative survival. Conclusion: Pre-treatment ADC values as well as changes in ADC values after treatment may provide useful information for predicting survival for patients with unresectable hepatocellular carcinoma.

  18. Brachial and lumbar plexuses in chronic inflammatory demyelinating polyradiculoneuropathy: MRI assessment including apparent diffusion coefficient

    Energy Technology Data Exchange (ETDEWEB)

    Adachi, Yuko; Sato, Noriko; Yamashita, Fumio; Kida, Jiro; Takahashi, Tomoyuki [National Center Hospital of Neurology and Psychiatry, Department of Radiology, Kodaira, Tokyo (Japan); Okamoto, Tomoko [National Center Hospital of Neurology and Psychiatry, Department of Neurology, Kodaira, Tokyo (Japan); Sasaki, Masayuki; Komaki, Hirofumi [National Center Hospital of Neurology and Psychiatry, Department of Child Neurology, Kodaira, Tokyo (Japan); Matsuda, Hiroshi [Saitama Medial University Hospital, Department of Nuclear Medicine, Iruma-gun, Saitama (Japan)

    2011-01-15

    Our purpose was to clarify the magnetic resonance (MR) imaging characteristics of the brachial and lumbar plexuses in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) using various kinds of sequences, including diffusion-weighted images (DWI). We evaluated the MR imaging findings for lumbar and/or brachial nerve plexuses in 13 CIDP patients and 11 normal volunteers. The nerve swelling was evaluated in comparison with normal controls by coronal short tau inversion recovery (STIR), and signal abnormalities were evaluated by coronal STIR, T1-weighted images, and DWIs. The degrees of contrast enhancement and apparent diffusion coefficient (ADC) values of the plexus were also assessed. In the patient group, diffuse enlargement and abnormally high signals were detected in 16 out of 24 plexuses (66.7%) on STIR, a slightly high signal was detected in 12 of 24 plexuses (50%) on T1-weighted images, and a high-intensity signal was detected in 10 of 18 plexuses (55.6%) on DWIs with high ADC values. Contrast enhancement of the plexuses was revealed in 6 of 19 plexuses (31.6%) and was mild in all cases. There were statistically significant differences between the ADC values of patients with either swelling or abnormal signals and those of both normal volunteers and patients without neither swelling nor abnormal signals. There were no relationships between MR imaging and any clinical findings. STIR is sufficient to assist clinicians in diagnosing CIDP. T1-weighted images and DWIs seemed useful for speculating about the pathological changes in swollen plexuses in CIDP patients. (orig.)

  19. Apparent diffusion coefifcient values of normal testis and variations with age

    Institute of Scientific and Technical Information of China (English)

    Athina C Tsili; Dimitrios Giannakis; Anastasios Sylakos; Alexandra Ntorkou; Loukas G Astrakas; Nikolaos Soifkitis; Maria I Argyropoulou

    2014-01-01

    The usefulness of diffusion-weighted magnetic resonance imaging (DWI) in the evaluation of scrotal pathology has recently been reported. A standard reference of normal testicular apparent diffusion coefifcient (ADC) values and their variations with age is necessary when interpreting normal testicular anatomy and pathology. We evaluated 147 normal testes using DWI, including 71 testes from 53 men aged 20-39 years (group 1), 67 testes from 42 men aged 40-69 years (group 2) and nine testes from six men older than 70 years (group 3). DWI was performed along the axial plane, using a single shot, multislice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm-2. The mean and standard deviation of the ADC values of normal testicular parenchyma were calculated for each age group separately. Analysis of variance (ANOVA) followed by post hoc analysis (Dunnett T3) was used for statistical purposes. The ADC values (× 10-3 mm2 s-1) of normal testicular tissue were different among age groups (group 1:1.08 ± 0.13;group 2:1.15 ± 0.15 and group 3:1.31 ± 0.22). ANOVA revealed differences in mean ADC among age groups (F=11.391, P<0.001). Post hoc analysis showed differences between groups 1 and 2 (P=0.008) and between groups 1 and 3 (P=0.043), but not between groups 2 and 3 (P=0.197). Our ifndings suggest that ADC values of normal testicular tissue increase with advancing age.

  20. Apparent diffusion coefficient values of normal testis and variations with age

    Directory of Open Access Journals (Sweden)

    Athina C Tsili

    2014-06-01

    Full Text Available The usefulness of diffusion-weighted magnetic resonance imaging (DWI in the evaluation of scrotal pathology has recently been reported. A standard reference of normal testicular apparent diffusion coefficient (ADC values and their variations with age is necessary when interpreting normal testicular anatomy and pathology. We evaluated 147 normal testes using DWI, including 71 testes from 53 men aged 20-39 years (group 1, 67 testes from 42 men aged 40-69 years (group 2 and nine testes from six men older than 70 years (group 3. DWI was performed along the axial plane, using a single shot, multislice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm−2 . The mean and standard deviation of the ADC values of normal testicular parenchyma were calculated for each age group separately. Analysis of variance (ANOVA followed by post hoc analysis (Dunnett T3 was used for statistical purposes. The ADC values (× 10−3 mm 2 s−1 of normal testicular tissue were different among age groups (group 1: 1.08 ± 0.13; group 2: 1.15 ± 0.15 and group 3: 1.31 ± 0.22. ANOVA revealed differences in mean ADC among age groups (F = 11.391, P < 0.001. Post hoc analysis showed differences between groups 1 and 2 (P = 0.008 and between groups 1 and 3 (P = 0.043, but not between groups 2 and 3 (P = 0.197. Our findings suggest that ADC values of normal testicular tissue increase with advancing age.

  1. Pressure Dependent Wall Relaxation in Polarized $^3$He Gaseous Cells

    CERN Document Server

    Peng, C; Chu, P -H; Gao, H; Zhang, Y

    2013-01-01

    Pressure dependence of longitudinal relaxation time (T$_1$) due to the cell wall was observed previously at both room temperature and low temperature in valved Rb-coated refillable $^3$He gaseous cells in \\cite{Zheng2}. The diffusion of $^3$He from measurement cell through a capillary tube to the valve and the subsequent depolarization on the surface of the valve was proposed to possibly explain such a pressure dependence at room temperature \\cite{Saam}. In this paper, we investigate this diffusion effect through measurements of T$_1$ with newly designed Rb-coated Pyrex glass cells at 295 K as well as finite element analysis (FEA) studies. Both the experimental results and FEA studies show that the diffusion effect is insufficient to explain the observed linear pressure-dependent behavior of T$_1$.

  2. Apparent diffusion coefficient evaluation for secondary changes in the cerebellum of rats after middle cerebral artery occlusion.

    Science.gov (United States)

    Yang, Yunjun; Gao, Lingyun; Fu, Jun; Zhang, Jun; Li, Yuxin; Yin, Bo; Chen, Weijian; Geng, Daoying

    2013-11-01

    Supratentorial cerebral infarction can cause functional inhibition of remote regions such as the cerebellum, which may be relevant to diaschisis. This phenomenon is often analyzed using positron emission tomography and single photon emission CT. However, these methods are expensive and radioactive. Thus, the present study quantified the changes of infarction core and remote regions after unilateral middle cerebral artery occlusion using apparent diffusion coefficient values. Diffusion-weighted imaging showed that the area of infarction core gradually increased to involve the cerebral cortex with increasing infarction time. Diffusion weighted imaging signals were initially increased and then stabilized by 24 hours. With increasing infarction time, the apparent diffusion coefficient value in the infarction core and remote bilateral cerebellum both gradually decreased, and then slightly increased 3-24 hours after infarction. Apparent diffusion coefficient values at remote regions (cerebellum) varied along with the change of supratentorial infarction core, suggesting that the phenomenon of diaschisis existed at the remote regions. Thus, apparent diffusion coefficient values and diffusion weighted imaging can be used to detect early diaschisis. PMID:25206615

  3. Hyperpolarised {sup 3}He MRI and {sup 81m}Kr SPECT in chronic obstructive pulmonary disease

    Energy Technology Data Exchange (ETDEWEB)

    Stavngaard, Trine [Copenhagen University Hospital, Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet (Denmark); Copenhagen University Hospital, Danish Research Centre for Magnetic Resonance, Hvidovre (Denmark); Soegaard, Lise Vejby; Hanson, Lars G. [Copenhagen University Hospital, Danish Research Centre for Magnetic Resonance, Hvidovre (Denmark); Mortensen, Jann; Berthelsen, Anne Kiil [Copenhagen University Hospital, Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet (Denmark); Schmiedeskamp, Joerg [Johannes Gutenberg Universitaet, Institut fuer Physik, Mainz (Germany); Dirksen, Asger [Gentofte University Hospital, Department of Respiratory Medicine, Hellerup (Denmark)

    2005-04-01

    During recent years, magnetic resonance imaging (MRI) using hyperpolarised (HP) {sup 3}He gas has emerged as a promising new method for the imaging of lung ventilation. However, systematic comparisons with nuclear medicine techniques have not yet been performed. The aim of this study was to compare ventilation imaging methods in 26 patients with chronic obstructive pulmonary disease (COPD) and nine lung healthy volunteers. HP {sup 3}He MRI, {sup 81m}Kr single-photon emission computed tomography (SPECT), high-resolution computed tomography (HRCT) and pulmonary function tests were performed. The three scans were scored visually as percentage of non-ventilated/diseased lung, and a computer-based objective measure of the ventilated volume in HP {sup 3}He MRI and {sup 81m}Kr SPECT and an emphysema index in HRCT were calculated. We found a good correlation between HP {sup 3}He MRI and {sup 81m}Kr SPECT for both visual defect score (r=0.80, p<0.0001) and objective estimate of ventilation (r=0.45, p=0.0157). In addition, both scans were well correlated with reference methods for the diagnosis of emphysema (pulmonary function test and HRCT). The defect scores were largest on {sup 81m}Kr SPECT (the score on HP {sup 3}He MRI was one-third less than that on {sup 81m}Kr SPECT), but the difference was reduced after normalisation for different breathing depths (HP {sup 3}He MRI at total lung capacity; {sup 81m}Kr SPECT at tidal breathing at functional residual capacity). HP {sup 3}He MRI provides detailed ventilation distribution images and defect scores are comparable on HP {sup 3}He MRI and {sup 81m}Kr SPECT. Additionally, new insights into the regional pulmonary microstructure via the apparent diffusion coefficient measurements are provided by HP {sup 3}He MRI. HP {sup 3}He MRI is a promising new diagnostic tool for the assessment of ventilation distribution. (orig.)

  4. Measurement of polarization of 3He with mobile polarized 3He neutron spin filter

    Science.gov (United States)

    Ino, T.; Kim, G. N.; Lee, M. W.; Lee, S. M.; Kim, J. Y.; Lee, S. W.; Skoy, V. R.

    2014-03-01

    A mobile polarized 3He neutron spin filter was developed for both optical pumping and transportation, and the polarization of 3He was measured with cold neutrons of HANARO in KAERI. The progress of polarization build-up during the optical pumping of the 3He cell was observed by adiabatic fast-passage NMR system. The 3He cell was made of an alumino-silicate glass GE-180 with a cylindrical shape of 40 mm in diameter and 60 mm in length from KEK. A cell contained 5.74 barṡcm of 3He gas. The whole installation after 8 h pumping was transported to the general-purpose test station of the HANARO research reactor and the polarization of 3He was measured with cold neutrons. The measured polarization of 3He was 0.18 ± 0.01 by measuring the neutron transmission through the 3He cell.

  5. Apparent Diffusion Coefficient (ADC) as a quantitative parameter in diffusion weighted MR imaging in gynecologic cancer: Dependence on b-values used

    DEFF Research Database (Denmark)

    Kallehauge, Jesper Folsted; Tanderup, Kari; Haack, Søren;

    2010-01-01

    Diffusion weighted imaging (DWI) has gained interest as an imaging modality for assessment of tumor extension and response to cancer treatment. The purpose of this study is to assess the impact of the choice of b-values on the calculation of the Apparent Diffusion Coefficient (ADC) for locally...

  6. Evaluation of true diffusion, perfusion factor, and apparent diffusion coefficient in non-necrotic liver metastases and uncomplicated liver hemangiomas using black-blood echo planar imaging

    NARCIS (Netherlands)

    K. Coenegrachts; J. Delanote; L. ter Beek; M. Haspeslagh; S. Bipat; J. Stoker; L. Steyaert; H. Rigauts

    2009-01-01

    PURPOSE: To assess the added value of true diffusion (D), perfusion factor (f) and apparent diffusion coefficient at low b-values (ADC(low)) for differentiation between liver metastases and hemangiomas based on respiratory-triggered high-resolution Black-Blood Single-Shot SpinEcho Echo Planar Imagin

  7. Diffusion-weighted imaging of the abdomen at 3.0 Tesla: image quality and apparent diffusion coefficient reproducibility compared with 1.5 Tesla.

    NARCIS (Netherlands)

    Rosenkrantz, A.B.; Oei, M.T.H.; Babb, J.S.; Niver, B.E.; Taouli, B.

    2011-01-01

    PURPOSE: To compare single-shot echo-planar imaging (SS EPI) diffusion-weighted MRI (DWI) of abdominal organs between 1.5 Tesla (T) and 3.0T in healthy volunteers in terms of image quality, apparent diffusion coefficient (ADC) values, and ADC reproducibility. MATERIALS AND METHODS: Eight healthy vol

  8. 3He melting pressure temperature scale

    DEFF Research Database (Denmark)

    Halperin, W.P.; Archie, C.N.; Richardson, R.C.;

    1976-01-01

    temperatures. The A feature of the melting curve which suggests itself as a thermometric fixed point is found to be T//A equals 2. 75 plus or minus 0. 11 mK. The agreement between this value and independent measurements of T//A, based on nuclear or electronic paramagnetism, Johnson noise thermometry......The latent heat for solidification of **3He has been measured along the **3He melting curve between 23 and 1 mK. A temperature scale is established which depends only on measurements of heat, pressure and volume, and on the condition that the entropy of solid **3He approaches R ln 2 at high...

  9. Density dependence of the single particle kinetic energy in {sup 3}He-{sup 4}He

    Energy Technology Data Exchange (ETDEWEB)

    Azuah, R.T. [Keele Univ. (United Kingdom). Dept. of Physics]|[Rutherford Appleton Lab., Chilton, Didcot (United Kingdom); Stirling, W.G. [Keele Univ. (United Kingdom). Dept. of Physics; Gibbs, M.R. [Keele Univ. (United Kingdom). Dept. of Physics; Sokol, P.E. [Dept. of Physics, Pennsylvania State Univ., University Park, PA (United States); Mayers, J. [Rutherford Appleton Lab., Chilton, Didcot (United Kingdom)

    1995-08-01

    We present inelastic neutron scattering measurements of liquid {sup 3}He-{sup 4}He mixtures at 1.5 K and at {sup 3}He concentrations of 0,15,40,70 and 100%. There is little apparent concentration dependence of the {sup 3}He kinetic energy, in disagreement with recent variational calculations for mixtures. The kinetic energy of the {sup 4}He component for the lower concentration mixtures is consistent with theoretical predictions. (orig.).

  10. Relationships between brain water content and diffusion tensor imaging parameters (apparent diffusion coefficient and fractional anisotropy) in multiple sclerosis

    International Nuclear Information System (INIS)

    Fifteen multiple sclerosis patients were examined by diffusion tensor imaging (DTI) to determine fractional anisotropy (FA) and apparent diffusion coefficient (ADC) in a superventricular volume of interest of 8 x 8 x 2 cm3 containing gray matter (GM) and white matter (WM) tissue. Point resolved spectroscopy 2D-chemical shift imaging of the same volume was performed without water suppression. The water contents and DTI parameters in 64 voxels of 2 cm3 were compared. The water content was increased in patients compared with controls (GM: 244±21 vs. 194±10 a.u.; WM: 245±32 vs. 190±11 a.u.), FA decreased (GM: 0.226±0.038 vs. 0.270±0.020; WM: 0.337±0.044 vs. 0.402±0.011) and ADC increased [GM: 1134±203 vs. 899±28 (x 10-6 mm2/s); WM: 901±138 vs. 751±17 (x 10-6 mm2/s)]. Correlations of water content with FA and ADC in WM were strong (r=-0.68, P<0.02; r=0.75; P<0.01, respectively); those in GM were weaker (r=-0.50, P<0.05; r=0.45, P<0.1, respectively). Likewise, FA and ADC were more strongly correlated in WM (r=-0.88; P<0.00001) than in GM (r=-0.69, P<0.01). The demonstrated relationship between DTI parameters and water content in multiple sclerosis patients suggests a potential for therapy monitoring in normal-appearing brain tissue. (orig.)

  11. Relationships between brain water content and diffusion tensor imaging parameters (apparent diffusion coefficient and fractional anisotropy) in multiple sclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Sijens, Paul E.; Irwan, Roy; Potze, Jan Hendrik; Oudkerk, Matthijs [University Medical Center Groningen and University of Groningen, Department of Radiology, Groningen (Netherlands); Mostert, Jop P.; Keyser, Jacques de [University Medical Center Groningen and University of Groningen, Department of Neurology, Groningen (Netherlands)

    2006-04-15

    Fifteen multiple sclerosis patients were examined by diffusion tensor imaging (DTI) to determine fractional anisotropy (FA) and apparent diffusion coefficient (ADC) in a superventricular volume of interest of 8 x 8 x 2 cm{sup 3} containing gray matter (GM) and white matter (WM) tissue. Point resolved spectroscopy 2D-chemical shift imaging of the same volume was performed without water suppression. The water contents and DTI parameters in 64 voxels of 2 cm{sup 3} were compared. The water content was increased in patients compared with controls (GM: 244{+-}21 vs. 194{+-}10 a.u.; WM: 245{+-}32 vs. 190{+-}11 a.u.), FA decreased (GM: 0.226{+-}0.038 vs. 0.270{+-}0.020; WM: 0.337{+-}0.044 vs. 0.402{+-}0.011) and ADC increased [GM: 1134{+-}203 vs. 899{+-}28 (x 10{sup -6} mm{sup 2}/s); WM: 901{+-}138 vs. 751{+-}17 (x 10{sup -6} mm{sup 2}/s)]. Correlations of water content with FA and ADC in WM were strong (r=-0.68, P<0.02; r=0.75; P<0.01, respectively); those in GM were weaker (r=-0.50, P<0.05; r=0.45, P<0.1, respectively). Likewise, FA and ADC were more strongly correlated in WM (r=-0.88; P<0.00001) than in GM (r=-0.69, P<0.01). The demonstrated relationship between DTI parameters and water content in multiple sclerosis patients suggests a potential for therapy monitoring in normal-appearing brain tissue. (orig.)

  12. Relationships between brain water content and diffusion tensor imaging parameters (apparent diffusion coefficient and fractional anisotropy) in multiple sclerosis.

    Science.gov (United States)

    Sijens, Paul E; Irwan, Roy; Potze, Jan Hendrik; Mostert, Jop P; De Keyser, Jacques; Oudkerk, Matthijs

    2006-04-01

    Fifteen multiple sclerosis patients were examined by diffusion tensor imaging (DTI) to determine fractional anisotropy (FA) and apparent diffusion coefficient (ADC) in a superventricular volume of interest of 8 x 8 x 2 cm(3) containing gray matter (GM) and white matter (WM) tissue. Point resolved spectroscopy 2D-chemical shift imaging of the same volume was performed without water suppression. The water contents and DTI parameters in 64 voxels of 2 cm(3) were compared. The water content was increased in patients compared with controls (GM: 244+/-21 vs. 194+/-10 a.u.; WM: 245+/-32 vs. 190+/-11 a.u.), FA decreased (GM: 0.226+/-0.038 vs. 0.270+/-0.020; WM: 0.337+/-0.044 vs. 0.402+/-0.011) and ADC increased [GM: 1134+/-203 vs. 899+/-28 (x10(-6) mm(2)/s); WM: 901+/-138 vs. 751+/-17 (x10(-6) mm(2)/s)]. Correlations of water content with FA and ADC in WM were strong (r=-0.68, P<0.02; r=0.75; P<0.01, respectively); those in GM were weaker (r=-0.50, P<0.05; r=0.45, P<0.1, respectively). Likewise, FA and ADC were more strongly correlated in WM (r=-0.88; P<0.00001) than in GM (r=-0.69, P<0.01). The demonstrated relationship between DTI parameters and water content in multiple sclerosis patients suggests a potential for therapy monitoring in normal-appearing brain tissue.

  13. Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions

    Energy Technology Data Exchange (ETDEWEB)

    Mahmoud, Omar M., E-mail: omarmostafa2008@yahoo.co [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Department of Radiology, South Egypt Cancer Institute, Assiut University, Assiut 71515 (Egypt); Tominaga, Atsushi, E-mail: atom@hiroshima-u.ac.j [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Amatya, Vishwa Jeet, E-mail: amatya@hiroshima-u.ac.j [Department of Pathology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551 (Japan); Ohtaki, Megu, E-mail: ohtaki@hiroshima-u.ac.j [Department of Environmetrics and Biometrics, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8551 (Japan); Sugiyama, Kazuhiko, E-mail: brain@hiroshima-u.ac.j [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Saito, Taiichi, E-mail: taiichi@hiroshima-u.ac.j [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Sakoguchi, Tetsuhiko, E-mail: sakog@hiroshima-u.ac.j [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Kinoshita, Yasuyuki, E-mail: d055634@hiroshima-u.ac.j [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Shrestha, Prabin, E-mail: prabinshrestha@hotmail.co [Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Abe, Nobukazu, E-mail: abebe@hiroshima-u.ac.j [Dept. of Clinical Radiology, Graduate School of Biomedical Sciences, Hiroshima Univ., Hiroshima 734-8551 (Japan)

    2010-06-15

    Objective: To evaluate the role of the apparent diffusion coefficient (ADC) using periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) diffusion weighted imaging (DWI) in the differentiation between sellar and parasellar mass lesions. Materials and methods: The study protocol was approved by our institutional review board. We retrospectively studied 60 patients with sellar and parasellar lesions who had undergone PROPELLER DWI on a 3-T MR imager. Conventional MRI findings were expressed as the ratio of signal intensity (SI) in the lesions to the normal white matter and the degree of contrast enhancement. ADC values were calculated as the minimum (ADC-MIN), mean (ADC-MEAN), and maximum (ADC-MAX). All patients underwent surgery and all specimens were examined histologically. Logistic discriminant analysis was performed by using the SI ratios on T1- and T2-weighted images (T1-WI, T2-WI), the degree of enhancement, and absolute ADC values as independent variables. Results: ADC-MIN of hemorrhagic pituitary adenomas was lower than of the other lesions with similar appearance on conventional MRI (non-hemorrhagic pituitary adenomas, craniopharyngiomas, Rathke's cleft cysts; accuracy 100%); the useful cut-off value was 0.700 x 10{sup -3} mm{sup 2}/s. ADC-MAX of meningiomas was lower than of non-hemorrhagic pituitary adenomas (accuracy 90.3%; p < 0.01). ADC-MIN of craniopharyngiomas was lower than of Rathke's cleft cysts (accuracy 100%; p < 0.05). Conclusion: As PROPELLER DWI is less sensitive to susceptibility artifacts than single-shot echoplanar DWI, it is more useful in the examination of sellar and parasellar lesions. Calculation of the ADC values helps to differentiate between various sellar and parasellar lesions.

  14. Apparent diffusion coefficient value of gastric cancer by diffusion-weighted imaging: Correlations with the histological differentiation and Lauren classification

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Song, E-mail: songliu532909756@gmail.com [Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Guan, Wenxian, E-mail: wenxianguan123@126.com [Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Wang, Hao, E-mail: wanghao20140525@126.com [Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Pan, Liang, E-mail: panliang2014@126.com [Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Zhou, Zhuping, E-mail: zhupingzhou@126.com [Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Yu, Haiping, E-mail: haipingyu2012@126.com [Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Liu, Tian, E-mail: tianliu2014@126.com [Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322 (United States); Yang, Xiaofeng, E-mail: xiaofengyang2014@126.com [Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322 (United States); He, Jian, E-mail: hjxueren@126.com [Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China); Zhou, Zhengyang, E-mail: zyzhou@nju.edu.cn [Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008 (China)

    2014-12-15

    Highlights: • Gastric cancers’ ADC values were significantly lower than normal gastric wall. • Gastric adenocarcinomas with different differentiation had different ADC values. • Gastric adenocarcinomas’ ADC values correlated with histologic differentiations. • Gastric cancers’ ADC values correlated with Lauren classifications. • Mean ADC value was better than min ADC value in characterizing gastric cancers. - Abstract: Objective: The purpose of this study was to evaluate the correlations between histological differentiation and Lauren classification of gastric cancer and the apparent diffusion coefficient (ADC) value of diffusion weighted imaging (DWI). Materials and methods: Sixty-nine patients with gastric cancer lesions underwent preoperative magnetic resonance imaging (MRI) (3.0T) and surgical resection. DWI was obtained with a single-shot, echo-planar imaging sequence in the axial plane (b values: 0 and 1000 s/mm{sup 2}). Mean and minimum ADC values were obtained for each gastric cancer and normal gastric walls by two radiologists, who were blinded to the histological findings. Histological type, degree of differentiation and Lauren classification of each resected specimen were determined by one pathologist. Mean and minimum ADC values of gastric cancers with different histological types, degrees of differentiation and Lauren classifications were compared. Correlations between ADC values and histological differentiation and Lauren classification were analyzed. Results: The mean and minimum ADC values of gastric cancers, as a whole and separately, were significantly lower than those of normal gastric walls (all p values <0.001). There were significant differences in the mean and minimum ADC values among gastric cancers with different histological types, degrees of differentiation and Lauren classifications (p < 0.05). Mean and minimum ADC values correlated significantly (all p < 0.001) with histological differentiation (r = 0.564, 0.578) and

  15. Apparent diffusion coefficient values and dynamic contrast enhancement patterns in differentiating seminomas from nonseminomatous testicular neoplasms

    International Nuclear Information System (INIS)

    Highlights: • Functional MRI in the characterization of testicular germ cell tumors was assessed. • ADC values proved useful in the characterization of testicular germ cell tumors. • Testicular germ cell tumors had similar enhancement patterns of dynamic MRI. - Abstract: Introduction: The aim of this study is to investigate the role of apparent diffusion coefficient (ADC) values and dynamic contrast enhancement (DCE) patterns in differentiating seminomas from nonseminomatous germ cell tumors (NSGCTs). Materials and methods: The MRI examinations of the scrotum of 26 men with histologically proven testicular GCTs were reviewed. DWI was performed in all patients, using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s/mm2. Subtraction DCE-MRI was performed in 20 cases using a 3D fast-field echo sequence after gadolinium administration. Time-signal intensity curves were created and semi-quantitative parameters (peak enhancement, time to peak, wash-in and wash-out rate) were calculated. The Student's t-test was used to compare the mean values of ADC, peak enhancement, time to peak, wash-in and wash-out rate between seminomas and NSGCTs. ROC analysis was also performed. Results: Histopathology disclosed the presence of 15 seminomas and 11 NSGCTs. The mean ± s.d. of ADC values (× 10−3 mm2/s) of seminomas (0.59 ± 0.009) were significantly lower than those of NSGCTs (0.90 ± 0.33) (P = 0.01). The optimal ADC cut-off value was 0.68 × 10−3 mm2/s. No differences between the two groups were observed for peak enhancement (P = 0.18), time to peak (P = 0.63) wash-in rate (P = 0.32) and wash-out rate (P = 0.18). Conclusions: ADC values may be used to preoperatively differentiate seminomas from NSGCTs

  16. The role of apparent diffusion coefficient values in detecting testicular intraepithelial neoplasia: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Tsili, Athina C., E-mail: a_tsili@yahoo.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Ntorkou, Alexandra, E-mail: alexdorkou@yahoo.com [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Baltogiannis, Dimitrios, E-mail: Greece.dbaltog@cc.uoi.gr [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Goussia, Anna, E-mail: agoussia@uoi.gr [Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Astrakas, Loukas G., E-mail: astrakas@uoi.gr [Department of Medical Physics, Medical School, University of Ioannina, 45110 Ioannina (Greece); Malamou-Mitsi, Vasiliki, E-mail: vmalamou@cc.uoi.gr [Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Sofikitis, Nikolaos, E-mail: akrosnin@hotmail.com [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Argyropoulou, Maria I., E-mail: margyrop@cc.uoi.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece)

    2015-05-15

    Highlights: • ADC values proved useful in the discrimination between TGCNs and normal testis. • Testicular intraepithelial neoplasia represents the precursor of most TGCNs. • ADC values cannot be used to detect testicular intraepithelial neoplasia. - Abstract: Introduction: The aim of this study is to improve detection of testicular intraepithelial neoplasia (TIN) by measurement of apparent diffusion coefficient (ADC) values. Materials and methods: Fifty-six MRI examinations of the scrotum, including 26 histologically proven testicular germ cell neoplasms were retrospectively evaluated. DWI was performed using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm{sup −2}. ADC measurements were classified into three groups according to their location: group 1 (n = 19), non-tumoral part, adjacent to testicular carcinoma, where the possible location of TIN was; group 2 (n = 26), testicular carcinoma; and group 3 (n = 60), normal testicular parenchyma. Analysis of variance (ANOVA) followed by post hoc analysis (Dunnett T3) was used for statistical purposes. Results: The mean ± s.d. of ADC values (×10{sup −3} mm{sup 2}/s) of different groups were: group 1, 1.08 ± 0.20; group 2, 0.72 ± 0.27; and group 3, 1.11 ± 0.14. ANOVA revealed differences of mean ADC between groups (F = 38.859, P < 0.001). Post hoc analysis showed differences between groups 2 and 3 (P < 0.001), groups 2 and 1 (P < 0.001), but not between groups 3 and 1 (P = 0.87). Conclusions: Based on our preliminary results, ADC values do not provide a reliable differentiation between TIN and testicular carcinoma or normal testicular parenchyma.

  17. Parameterization of the Age-Dependent Whole Brain Apparent Diffusion Coefficient Histogram

    Directory of Open Access Journals (Sweden)

    Uwe Klose

    2015-01-01

    Full Text Available Purpose. The distribution of apparent diffusion coefficient (ADC values in the brain can be used to characterize age effects and pathological changes of the brain tissue. The aim of this study was the parameterization of the whole brain ADC histogram by an advanced model with influence of age considered. Methods. Whole brain ADC histograms were calculated for all data and for seven age groups between 10 and 80 years. Modeling of the histograms was performed for two parts of the histogram separately: the brain tissue part was modeled by two Gaussian curves, while the remaining part was fitted by the sum of a Gaussian curve, a biexponential decay, and a straight line. Results. A consistent fitting of the histograms of all age groups was possible with the proposed model. Conclusions. This study confirms the strong dependence of the whole brain ADC histograms on the age of the examined subjects. The proposed model can be used to characterize changes of the whole brain ADC histogram in certain diseases under consideration of age effects.

  18. Value of Apparent Diffusion Coefficient(ADC) of Diffusion eighted Magnetic Resonance Imaging in Common Renal Disease Diagnosis

    Institute of Scientific and Technical Information of China (English)

    Yuelang Zhang; Xingwang Sun; Guangnan Quan; Yongqian Qiang; Chenxia Li

    2008-01-01

    Objective:To find the value of the apparent diffusion coefficient (ADC) of diffusion weighted magnetic resonance imaging of common renal diseases. Methods: There were 30 healthy subjects and 81 patients with renal lesions (56 cases of renal carcinoma, 18 lesions of 12 cases of renal angiomyolipoma, and 21 lesions of 13 cases of renal cysts). Conventional magnetic resonance imaging and diffusion weighted magnetic resonance imaging were carded out. We measured the average ADC value of the renal lesions and normal kidneys. ADC maps from different b values were generated by a statistical package. Results: The ADC values of normal kidneys with three different motion-probing gradients(b=500, 800, 1000 sec/mm2) were 2.78±0.14×10-3mm2s-1,2.45±0.13×10-3mm2s-1, 2.13±0.14×10-3mm2s-1, respectively. The ADC values of renal cell carcinoma with three different motion-probing gradients(b=500, 800, 1008 sec/mm2) were 1.63±0.14×10-3mm2s-1, 1.31±0.18×10-3mm2s-1, 1.07±0.15-310-3mm2s-1, respectively. Among the renal cell carcinoma, the ADC value of clear cell type were 1.67±0.09×10-3mm2s-1, 1.36±0.13×10-3mm2s-1, 1.15±0.14×10-3mm2s-1,respectively; the ADC values of granular cell type were 1.59±0.19×10-3mm2s-1, 1.25±0.22×10-3mm2s-1, 0.97±0.12×10-3mm2s-1, respectively. The ADC values of renal angiomyolipoma with three different motion-probing gradients(b=500, 800, 1008 sec/mm2) were 0.88±0.08×10-3mm2s-1, 0.63±0.07×10-3mm2s-1, 0.43±0.04×10-3mm2s-1, respectively. The ADC values of renal cystic lesions with three different motion-probing gradients(b=500, 800, 1000 sec/mm2) were 3.73±0.18×10-3mm2s-1, 3.44±0.13×10-3mm2s-1, 3.09±0.21×10-3mm2s-1, respectively. Statistically significant differences exists between the ADC values of normal kidney, renal carcinomas, renal angiomyolipomas and renal cysts when the b value is the same. Among the different cell types of renal carcinomas, the ADC value of granular cell carcinoma is lower than that of clear cell

  19. Fluctuations above the superfluid transition in liquid 3He

    International Nuclear Information System (INIS)

    It is shown that fluctuations above the superfluid transition in liquid 3He depend strongly upon the relative angular momentum l of a Cooper pair but are insensitive to the fourth order term in the Ginsburg-Landau free energy. The effects are shown to be observable in the static magnetization, viscosity and spin diffusion and give a means of determining the value of l. (U.S.)

  20. Diffusion-weighted MRI of epithelial ovarian cancers: Correlation of apparent diffusion coefficient values with histologic grade and surgical stage

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Ji-Won, E-mail: fromentin@naver.com [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Rha, Sung Eun, E-mail: serha@catholic.ac.kr [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Oh, Soon Nam, E-mail: hiohsn@catholic.ac.kr [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Park, Michael Yong, E-mail: digirave@kmle.com [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Byun, Jae Young, E-mail: jybyun@catholic.ac.kr [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Lee, Ahwon, E-mail: klee@catholic.ac.kr [Department of Hospital Pathology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of)

    2015-04-15

    Highlights: •The solid component of all invasive epithelial cancers showed high b{sub 1000} signal intensity. •ADCs can predict the histologic grade of epithelial ovarian cancer. •ADCs correlate negatively to the surgical stage of epithelial ovarian cancer. •ADCs may be useful imaging biomarkers to assess epithelial ovarian cancer. -- Abstract: Objective: The purpose of this article is to correlate the apparent diffusion coefficient (ADC) values of epithelial ovarian cancers with histologic grade and surgical stage. Materials and methods: We enrolled 43 patients with pathologically proven epithelial ovarian cancers for this retrospective study. All patients underwent preoperative pelvic magnetic resonance imaging (MRI) including diffusion-weighted images with b value of 0 and 1000 s/mm{sup 2} at 3.0-T unit. The mean ADC values of the solid portion of the tumor were measured and compared among different histologic grades and surgical stages. Results: The mean ADC values of epithelial ovarian cancers differed significantly between grade 1 (well-differentiated) and grade 2 (moderately-differentiated) (P = 0.013) as well as between grade 1 and grade 3 (poorly-differentiated) (P = 0.01); however, no statistically significant difference existed between grade 2 and grade 3 (P = 0.737). The receiver-operating characteristic analysis indicated that a cutoff ADC value of less than or equal to 1.09 × 10{sup −3} mm{sup 2}/s was associated with 94.4% sensitivity and 85.7% specificity in distinguishing grade 1 and grade 2/3 cancer. The difference in mean ADC values was statistically significant for early stage (FIGO stage I) and advanced stage (FIGO stage II-IV) cancer (P = 0.011). The interobserver agreement for the mean ADC values of epithelial ovarian cancers was excellent. Conclusion: The mean ADC values of the solid portion of epithelial ovarian cancers negatively correlated to histologic grade and surgical stage. The mean ADC values may be useful imaging

  1. Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas

    Energy Technology Data Exchange (ETDEWEB)

    Mahmoud, Omar M. [Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Department of Radiology, South Egypt Cancer Institute, Assiut University, Assiut 71515 (Egypt); Tominaga, Atsushi [Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Amatya, Vishwa Jeet [Department of Pathology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551 (Japan); Ohtaki, Megu [Department of Environmetrics and Biometrics, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8551 (Japan); Sugiyama, Kazuhiko; Sakoguchi, Tetsuhiko; Kinoshita, Yasuyuki [Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Takeshima, Yukio [Department of Pathology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551 (Japan); Abe, Nobukazu; Akiyama, Yuji [Department of Clinical Radiology, Hiroshima University Hospital, Hiroshima 734-8551 (Japan); El-Ghoriany, Ahmad I. [Department of Neurosurgery, Faculty of Medicine, Assiut University, Assiut 71515 (Egypt); Alla, Abdel Karim H. Abd; El-Sharkawy, Mostafa A.M. [Department of Radiology, Faculty of Medicine, Assiut University, Assiut 71515 (Egypt); Arita, Kazunori [Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima (Japan); Kurisu, Kaoru [Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan); Yamasaki, Fumiyuki, E-mail: fyama@hiroshima-u.ac.jp [Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551 (Japan)

    2011-11-15

    Objective: The relationship between tumor consistency and apparent diffusion coefficient (ADC) values is controversial. We evaluated the role of the ADC using an advanced diffusion-weighted imaging (DWI) technique. We employed periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) DWI acquired on a 3-T magnetic resonance imaging (MRI) scanner to assess the consistency of pituitary adenomas and examined the relationship between the ADC and the hormone secretion status of the tumors and their MIB-1 labeling index (MIB-1 LI). Materials and methods: The study protocol was approved by our institutional review board. We retrospectively studied 24 operated patients with pituitary adenomas who had undergone PROPELLER DWI on a 3-T MRI scanner. Conventional MRI findings were expressed as the ratio of the signal intensity (SI) in the lesions to the SI of the normal white matter and the degree of contrast enhancement. Minimum-, mean-, and maximum ADC (ADC{sub min}, ADC{sub mean}, ADC{sub max}) values were calculated. The consistency of the tumors was determined by neurosurgeons. All surgical specimens were submitted for histological study to calculate the MIB-1 LI and the percent collagen content. Preoperative MRI-, intraoperative-, and histological findings were analyzed by a statistician. Results: Our study included 15 soft-, 5 fibrous-, and 4 hard tumors. Tumor consistency was strongly associated with the percent collagen content. However, neither the tumor consistency nor the percent collagen content was correlated with MRI findings or ADC values. The SI of growth hormone-producing adenomas on T2-WI was lower than of the other pituitary adenomas studied (p < 0.01); no other significant difference was found in the ADC or on conventional MRI between pituitary adenomas with different secretory functions. The MIB-1 LI of pituitary adenomas was not correlated with their appearance on conventional MRI or their ADC values. Conclusion: Using the

  2. Diffusion-weighted magnetic resonance imaging of the normal endometrium: temporal and spatial variations of the apparent diffusion coefficient

    Energy Technology Data Exchange (ETDEWEB)

    Fornasa, Francesca; Montemezzi, Stefania [Dept. of Radiology, San Bonifacio Hospital, Verona (Italy)], e-mail: francescafornasa@libero.it

    2012-06-15

    Background: Diffusion-weighted magnetic resonance imaging (DWI) is increasingly used in the diagnosis of endometrial disease. No complete knowledge, however, exists yet of the influence of physiology on the endometrial apparent diffusion coefficient (ADC) values on which DWI is based. Purpose: To establish whether the ADC values measured with DWI in the endometrium of healthy reproductive-aged women significantly vary from the early proliferative to the periovulatory phase of the menstrual cycle and between the fundus and the isthmus of the uterus. Material and Methods: In 17 women the endometrial ADC values measured on the fifth menstrual day, both at the fundus and at the isthmus of the uterus, were compared to the values obtained on the 14th day before the subsequent cycle. In 81 women (menstrual day: fifth through 21st) the endometrial ADC values measured at the fundus were compared to the values obtained at the isthmus of the uterus. All examinations were performed with a 1.5 T magnet (b values: 0 and 800 mm/s{sup 2}). The results were analyzed by means of Student's t-test per paired data. Results: The endometrial ADC values measured on the fifth day of the menstrual cycle were lower than those obtained in the periovulatory phase both at the fundus (mean 0.923 vs. 1.256 x 10{sup -}3 mm{sup 2}/s) and at the isthmus (mean 1.297 vs. 1.529 x 10{sup -}3 mm{sup 2}/s) of the uterus. The endometrial ADC values measured at the fundus of the uterus were lower than those obtained at the isthmus (mean 1.132 vs. 1.420 x 10{sup -}3 mm{sup 2}/s) through the menstrual cycle. All these differences were highly significant (P < 0.001) at statistical analysis. Conclusion: Physiological variations occurring in endometrial ADC values of healthy women should be considered by the radiologists when interpreting DWI examinations in patients with endometrial disease.

  3. Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas

    International Nuclear Information System (INIS)

    Objective: The relationship between tumor consistency and apparent diffusion coefficient (ADC) values is controversial. We evaluated the role of the ADC using an advanced diffusion-weighted imaging (DWI) technique. We employed periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) DWI acquired on a 3-T magnetic resonance imaging (MRI) scanner to assess the consistency of pituitary adenomas and examined the relationship between the ADC and the hormone secretion status of the tumors and their MIB-1 labeling index (MIB-1 LI). Materials and methods: The study protocol was approved by our institutional review board. We retrospectively studied 24 operated patients with pituitary adenomas who had undergone PROPELLER DWI on a 3-T MRI scanner. Conventional MRI findings were expressed as the ratio of the signal intensity (SI) in the lesions to the SI of the normal white matter and the degree of contrast enhancement. Minimum-, mean-, and maximum ADC (ADCmin, ADCmean, ADCmax) values were calculated. The consistency of the tumors was determined by neurosurgeons. All surgical specimens were submitted for histological study to calculate the MIB-1 LI and the percent collagen content. Preoperative MRI-, intraoperative-, and histological findings were analyzed by a statistician. Results: Our study included 15 soft-, 5 fibrous-, and 4 hard tumors. Tumor consistency was strongly associated with the percent collagen content. However, neither the tumor consistency nor the percent collagen content was correlated with MRI findings or ADC values. The SI of growth hormone-producing adenomas on T2-WI was lower than of the other pituitary adenomas studied (p < 0.01); no other significant difference was found in the ADC or on conventional MRI between pituitary adenomas with different secretory functions. The MIB-1 LI of pituitary adenomas was not correlated with their appearance on conventional MRI or their ADC values. Conclusion: Using the PROPELLER DWI

  4. Photodisintegration of 3H and 3He

    International Nuclear Information System (INIS)

    The photoneutron cross sections for 3H and 3He have been measured from threshold to approx. 25 MeV with monoenergetic photons from the annihilation in flight of fast positrons at the LLL Electron-Positron Linear Accelerator facility. These reactions include the two-body breakup of 3H and the three-body breakup of both 3H and 3He; these measurements for 3H are the first to span the energy region across the peaks of the cross sections. An efficient BF3-tube-and-paraffin neutron detector and high-pressure gaseous samples of several moles each (the activity of the 3H sample was approx. 200,000 Ci) were employed in these measurements. Measurements on 16O and 2H also were performed to verify the absolute cross-section scale. The results, when compared with each other and with results for the two-body breakup cross section for 3He from the literature, show that the two-body breakup cross sections for 3H and 3He have nearly the same shape, but the one for 3He lies lower in magnitude; the three-body breakup cross section for 3He lies higher in magnitude and is broader in the peak region and also rises less sharply from threshold than that for 3H; and these measured differences between the cross sections for the breakup modes largely compensate in their sum, so that the total photon absorption cross sections for 3H and 3He are nearly the same in both size and shape at energies near and above their peaks. Theoretical results from the literature disagree with the experimental results to a certain extent over the entire photon-energy region for which the photoneutron cross sections were measured. 50 figures, 7 tables

  5. Pancreatic cancer: Lack of association between apparent diffusion coefficient values and adverse pathological features

    International Nuclear Information System (INIS)

    Aim: To identify retrospectively potential associations between apparent diffusion coefficient (ADC) values of pancreatic adenocarcinoma and tumour grade as well as other pathological features, using histopathological assessment from the Whipple procedure as the reference standard. Materials and methods: Thirty patients with pancreatic adenocarcinoma underwent magnetic resonance imaging (MRI) including diffusion-weighted imaging with b-values of 0 and 500 s/mm2 before the Whipple procedure. Two radiologists independently recorded the ADC values of the tumour and benign pancreas for all cases. ADC values were compared with histopathological findings following the Whipple procedure. Results: The intra-class correlation coefficient was 0.689 for benign pancreas and 0.695 for tumours, indicating good inter-reader agreement for ADC values. The mean ADC value was significantly lower in tumours than in benign pancreas for both readers (reader 1: 1.74 ± 0.34 × 10−3 mm2/s versus 2.08 ± 0.48 × 10−3 mm2/s, respectively, p = 0.006; reader 2: 1.69 ± 0.41 × 10−3 mm2/s versus 2.11 ± 0.54 × 10−3 mm2/s, respectively, p −3 mm2/s versus 1.78 ± 0.33 × 10−3 mm2/s, respectively, p = 0.491; reader 2: 1.62 ± 0.33 × 10−3 mm2/s versus 1.75 ± 0.49 × 10−3 mm2/s, respectively, p = 0.405). The area under the curve (AUC) for differentiation of poorly and well/moderately differentiated tumours was 0.611 and 0.596 for readers 1 and 2, respectively, and was not significantly better than an AUC of 0.500 for either reader (p ≥ 0.306). In addition, ADC was not significantly different for either reader between tumours with stage T3 versus stage T1/T2, between tumours with and without metastatic peri-pancreatic lymph nodes, or between tumours located in the pancreatic head versus other pancreatic regions (p ≥ 0.413). Conclusion: No associations between ADC values of pancreatic adenocarcinoma and tumour grade or other adverse pathological features were observed

  6. Apparent diffusion coefficient values and dynamic contrast enhancement patterns in differentiating seminomas from nonseminomatous testicular neoplasms

    Energy Technology Data Exchange (ETDEWEB)

    Tsili, Athina C., E-mail: a_tsili@yahoo.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Sylakos, Anastasios, E-mail: anasylakos@yahoo.gr [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Ntorkou, Alexandra, E-mail: alexdorkou@yahoo.com [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Stavrou, Sotirios, E-mail: s.sotiris@yahoo.gr [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Astrakas, Loukas G., E-mail: astrakas@uoi.gr [Department of Medical Physics, Medical School, University of Ioannina, 45110 Ioannina (Greece); Sofikitis, Nikolaos, E-mail: akrosnin@hotmail.com [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Argyropoulou, Maria I., E-mail: margyrop@cc.uoi.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece)

    2015-07-15

    Highlights: • Functional MRI in the characterization of testicular germ cell tumors was assessed. • ADC values proved useful in the characterization of testicular germ cell tumors. • Testicular germ cell tumors had similar enhancement patterns of dynamic MRI. - Abstract: Introduction: The aim of this study is to investigate the role of apparent diffusion coefficient (ADC) values and dynamic contrast enhancement (DCE) patterns in differentiating seminomas from nonseminomatous germ cell tumors (NSGCTs). Materials and methods: The MRI examinations of the scrotum of 26 men with histologically proven testicular GCTs were reviewed. DWI was performed in all patients, using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s/mm{sup 2}. Subtraction DCE-MRI was performed in 20 cases using a 3D fast-field echo sequence after gadolinium administration. Time-signal intensity curves were created and semi-quantitative parameters (peak enhancement, time to peak, wash-in and wash-out rate) were calculated. The Student's t-test was used to compare the mean values of ADC, peak enhancement, time to peak, wash-in and wash-out rate between seminomas and NSGCTs. ROC analysis was also performed. Results: Histopathology disclosed the presence of 15 seminomas and 11 NSGCTs. The mean ± s.d. of ADC values (× 10{sup −3} mm{sup 2}/s) of seminomas (0.59 ± 0.009) were significantly lower than those of NSGCTs (0.90 ± 0.33) (P = 0.01). The optimal ADC cut-off value was 0.68 × 10{sup −3} mm{sup 2}/s. No differences between the two groups were observed for peak enhancement (P = 0.18), time to peak (P = 0.63) wash-in rate (P = 0.32) and wash-out rate (P = 0.18). Conclusions: ADC values may be used to preoperatively differentiate seminomas from NSGCTs.

  7. Photoproduction of eta-mesic 3He

    CERN Document Server

    Pfeiffer, M; Annand, J R M; Beck, R; Caselotti, G; Cherepnya, S N; Föhl, K; Fog, L S; Hornidge, D; Janssen, S; Kashevarov, V; Kondratiev, R; Kotulla, M; Krusche, B; McGeorge, J C; MacGregor, I J D; Mengel, K; Messchendorp, J G; Metag, V; Novotny, R; Rost, M; Sack, S; Sanderson, R; Schadmand, S; Thomas, A; Watts, D P

    2003-01-01

    The photoproduction of eta-mesic 3He has been investigated using the TAPS calorimeter at the Mainz Microtron accelerator facility MAMI. The total inclusive cross section for the reaction gamma+3He->eta+X has been measured for photon energies from threshold to 820 MeV. The total and angular differential coherent eta cross sections have been extracted up to energies of 745 MeV. A resonance-like structure just above the eta production threshold with an isotropic angular distribution suggests the existence of a resonant quasi-bound state. This is supported by studies of a competing decay channel of such a quasi-bound eta-mesic nucleus into pi^0+p+X. A binding energy of (4+-4) MeV and a width of (25+-6) MeV is deduced for the quasi-bound eta-mesic state in 3He.

  8. Quantum prewetting transitions in liquid 3He

    International Nuclear Information System (INIS)

    Multilayer 3He film growth on weak-binding alkali substrates is investigated with a non-local density functional theory. Although 3He wets all substrates, prewetting transitions are predicted to occur on cesium and potassium. Emphasis is put on the role played by the Fermi statistics. Prewetting critical temperatures are estimated. Continuous wetting at zero temperature is recovered with increasing strength of substrate potential. The heat capacity and the magnetization of the films exhibits steps associated with the occupation of two-dimensional (2D) Fermi discs. (authors). 24 refs., 4 figs

  9. Progression of Emphysema Evaluated by MRI Using Hyperpolarized 3He (HP 3He Measurements in Patients with Alpha-1-Antitrypsin (A1AT) Deficiency Compared with CT and Lung Function Tests

    International Nuclear Information System (INIS)

    Background: The progression of emphysema is traditionally measured by pulmonary function test, with forced expiratory volume in 1 s (FEV1) being the most accepted and used measurement. However, FEV1 is insensitive in detecting mild/slow progression of emphysema because of low reproducibility as compared to yearly decline. Purpose: To investigate the progression of emphysema over a period of 2 years using diffusion-weighted hyperpolarized (HP) 3He magnetic resonance imaging (MRI) in patients with alpha-1-antitrypsin (A1AT) deficiency. Material and Methods: Nine patients with severe A1AT deficiency were studied over a period of 2 years (baseline, year 1, and year 2) with HP 3He MRI using apparent diffusion coefficient (ADC), lung function tests (FEV1 and carbon monoxide lung diffusion capacity [DL,CO]), and computed tomography (CT) using densitometric parameters (15th percentile density [CT-PD15] and relative area of emphysema below -910 HU [CT-RA-910]). Results: Seven patients were scanned three times, one patient two times, and one patient only at baseline. The mean increase in ADC values from first to last HP 3He MR scanning was 3.8% (0.014 cm2/s [SD 0.024 cm2/s]; not significant). The time trends for FEV1, DL,CO, CT-PD15, and CT-RA-910 were all statistically significant. We found a high correlation between ADC and DL,CO (P3He MRI for monitoring the progression of emphysema. However, in the future, larger studies are needed to confirm these preliminary results

  10. Progression of Emphysema Evaluated by MRI Using Hyperpolarized 3He (HP 3He) Measurements in Patients with Alpha-1-Antitrypsin (A1AT) Deficiency Compared with CT and Lung Function Tests

    Energy Technology Data Exchange (ETDEWEB)

    Stavngaard, T.; Vejby Soegaard, L. (Danish Research Center for Magnetic Resonance, Copenhagen Univ. Hospital Hvidovre, Hvidovre (Denmark)); Batz, M. (Inst. of Physics, Johannes Gutenberg Univ., Mainz (Germany)); Schreiber, L.M. (Dept. of Interventional and Diagnostic Radiology, Johannes Gutenberg Univ. Medical School, Mainz (Germany)); Dirksen, A. (Dept. of Respiratory Medicine, Gentofte Hospital, Univ. of Copenhagen, Copenhagen (Denmark))

    2009-11-15

    Background: The progression of emphysema is traditionally measured by pulmonary function test, with forced expiratory volume in 1 s (FEV1) being the most accepted and used measurement. However, FEV1 is insensitive in detecting mild/slow progression of emphysema because of low reproducibility as compared to yearly decline. Purpose: To investigate the progression of emphysema over a period of 2 years using diffusion-weighted hyperpolarized (HP) 3He magnetic resonance imaging (MRI) in patients with alpha-1-antitrypsin (A1AT) deficiency. Material and Methods: Nine patients with severe A1AT deficiency were studied over a period of 2 years (baseline, year 1, and year 2) with HP 3He MRI using apparent diffusion coefficient (ADC), lung function tests (FEV1 and carbon monoxide lung diffusion capacity [DL,CO]), and computed tomography (CT) using densitometric parameters (15th percentile density [CT-PD15] and relative area of emphysema below -910 HU [CT-RA-910]). Results: Seven patients were scanned three times, one patient two times, and one patient only at baseline. The mean increase in ADC values from first to last HP 3He MR scanning was 3.8% (0.014 cm2/s [SD 0.024 cm2/s]; not significant). The time trends for FEV1, DL,CO, CT-PD15, and CT-RA-910 were all statistically significant. We found a high correlation between ADC and DL,CO (P<0.001). Conclusion: This pilot study indicates the possible use of nonionizing HP 3He MRI for monitoring the progression of emphysema. However, in the future, larger studies are needed to confirm these preliminary results

  11. Assessment and quantification of sources of variability in breast apparent diffusion coefficient (ADC) measurements at diffusion weighted imaging

    Energy Technology Data Exchange (ETDEWEB)

    Giannotti, E., E-mail: ytteb84@hotmail.com [Breast Imaging Department, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Waugh, S., E-mail: shelley.waugh@nhs.net [Department of Medical Physics, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Department of Clinical Radiology, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Priba, L., E-mail: lpriba@nhs.net [Department of Medical Physics, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Davis, Z., E-mail: zoedavis@doctors.org.uk [Breast Imaging Department, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Crowe, E., E-mail: e.crowe@nhs.net [Department of Clinical Radiology, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Vinnicombe, S., E-mail: s.vinnicombe@dundee.ac.uk [Division of Imaging and Technology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY (United Kingdom)

    2015-09-15

    Highlights: • Inter-scan errors have minimal contribution to ADC measurement variability. • Intra-observer measures of ADC values in breast cancer are excellent. • ADC measures in whole tumour are more reproducible than minimum ADC measures. • ADC measurement error is most influenced by multiple readers. - Abstract: Purpose: Apparent Diffusion Coefficient (ADC) measurements are increasingly used for assessing breast cancer response to neoadjuvant chemotherapy although little data exists on ADC measurement reproducibility. The purpose of this work was to investigate and characterise the magnitude of errors in ADC measures that may be encountered in such follow-up studies- namely scanner stability, scan–scan reproducibility, inter- and intra- observer measures and the most reproducible measurement of ADC. Methods: Institutional Review Board approval was obtained for the prospective study of healthy volunteers and written consent acquired for the retrospective study of patient images. All scanning was performed on a 3.0-T MRI scanner. Scanner stability was assessed using an ice-water phantom weekly for 12 weeks. Inter-scan repeatability was assessed across two scans of 10 healthy volunteers (26–61 years; mean: 44.7 years). Inter- and intra-reader analysis repeatability was measured in 52 carcinomas from clinical patients (29–70 years; mean: 50.0 years) by measuring the whole tumor ADC value on a single slice with maximum tumor diameter (ADC{sub S}) and the ADC value of a small region of interest (ROI) on the same slice (ADC{sub min}). Repeatability was assessed using intraclass correlation coefficients (ICC) and coefficients of repeatability (CoR). Results: Scanner stability contributed 6% error to phantom ADC measurements (0.071 × 10{sup −3} mm{sup 2}/s; mean ADC = 1.089 × 10{sup −3} mm{sup 2}/s). The measured scan-scan CoR in the volunteers was 0.122 × 10{sup −3} mm{sup 2}/s, contributing an error of 8% to the mean measured values (ADC

  12. {sup 3}He retention and structural evolution in erbium tritides: Phase and aging effects

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, X.S., E-mail: zlxs77@163.com [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Thin Film Centre, Scottish Universities Physics Alliance (SUPA), University of West of Scotland, Paisley PA1 2BE, Scotland (United Kingdom); Zhang, L.; Wang, W.D.; Liu, Q. [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Peng, S.M., E-mail: pengshuming@caep.cn [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Ding, W.; Long, X.G.; Cheng, G.J.; Liang, J.H. [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Fu, Y.Q. [Thin Film Centre, Scottish Universities Physics Alliance (SUPA), University of West of Scotland, Paisley PA1 2BE, Scotland (United Kingdom)

    2015-06-15

    Highlights: • Effects of phase changes on {sup 3}He retention of Er tritide films were investigated. • The α phase in Er tritide films had no apparent effect on {sup 3}He release/retention. • Tritium content in the β phase showed significant effects on {sup 3}He retention. • Evolution of {sup 3}He in the β phase was apparently influenced by the γ phase. • Effects of phase changes on structure evolution of Er tritides were investigated. - Abstract: Effects of phase changes on {sup 3}He release/retention and crystal lattice evolution during aging of erbium (Er) tritide films were investigated using X-ray diffraction. The contents of α phase and γ phase in the Er tritide films showed significant different effects on {sup 3}He release/retention. The initial tritium stoichiometry or excess tritium atoms accommodated in the octahedral sites and the microstructure (i.e., the texture and Er{sub 2}O{sub 3} oxide inclusions) played an important role for the {sup 3}He release and the evolution of {sup 3}He bubbles in the β phase Er tritide films. In the β + γ region, evolution of {sup 3}He in the β phase was apparently influenced by the γ phase, which could result in a strongly anisotropic lattice dilation and an earlier inflection point of the expansion rate of (1 1 1) lattice parameter. A preferred occupation of {sup 3}He in basal plane of the hexagonal γ phase and the lattice expansion along the hexagonal direction were identified.

  13. Orientationally invariant metrics of apparent compartment eccentricity from double pulsed field gradient diffusion experiments

    DEFF Research Database (Denmark)

    Jespersen, Sune Nørhøj; Lundell, Henrik; Sønderby, Casper Kaae;

    2013-01-01

    Pulsed field gradient diffusion sequences (PFG) with multiple diffusion encoding blocks have been indicated to offer new microstructural tissue information, such as the ability to detect nonspherical compartment shapes in macroscopically isotropic samples, i.e. samples with negligible directional...... signal dependence on diffusion gradients in standard diffusion experiments. However, current acquisition schemes are not rotationally invariant in the sense that the derived metrics depend on the orientation of the sample, and are affected by the interplay of sampling directions and compartment...... orientation dispersion when applied to macroscopically anisotropic systems. Here we propose a new framework, the d-PFG 5-design, to enable rotationally invariant estimation of double wave vector diffusion metrics (d-PFG). The method is based on the idea that an appropriate orientational average of the signal...

  14. Extraterrestrial 3He in marine polymetallic nodules: a potential method for measuring growth rate of nodules

    Institute of Scientific and Technical Information of China (English)

    李延河; 宋鹤彬; 李金城

    2002-01-01

    The comparative measurements of helium isotope compositions between marine polymetallic nodules and their surrounding sediments, their magnetic fractions and bulk from C-C Zone of the East Pacific Basin are reported. The 4He content and 3He/4He ratio of polymetallic nodules and their surrounding sediments are extremely high; the 3He, 4He concentrations and most 3He/4He ratios of magnetic fractions in nodules and sediments are apparently higher than those in bulk. The helium isotope data points of nodules and sediments are all distributed along or closely to the mixing curve of the interplanetary dust particles (IDPs) and the terrigenous sediments in the chart of 3He-3He/4He. In the same sampling site, the 3He/4He ratios of nodules and their surrounding sediments are very similar, and the changes of both ratios are synchronous. It shows that the high 3He/4He ratios in nodules and sediments may all result from IDPs. So, if the flux of extraterrestrial 3He into the nodules and sediments is constant, the growth rate of polymetallic nodules and the sedimentation rate of sediments can be independently calculated according to the concentration of extraterrestrial 3He in nodules and sediments.

  15. Apparent diffusive motion of centrin foci in living cells: implications for diffusion-based motion in centriole duplication

    OpenAIRE

    Rafelski, Susanne M.; Keller, Lani C.; Alberts, Jonathan B.; Marshall, Wallace F

    2011-01-01

    The degree to which diffusion contributes to positioning cellular structures is an open question. Here we investigate the question of whether diffusive motion of centrin granules would allow them to interact with the mother centriole. The role of centrin granules in centriole duplication remains unclear, but some proposed functions of these granules, for example in providing pre-assembled centriole subunits, or by acting as unstable “pre-centrioles” that need to be captured by the mother cent...

  16. The apparent diffusion coefficient of water in gray and white matter of the infant brain

    DEFF Research Database (Denmark)

    Toft, P B; Leth, H; Peitersen, Birgit;

    1996-01-01

    at the basal ganglia level was investigated with the diffusion-encoding gradients in the slice-selection direction. RESULTS: On ADC maps, the corpus callosum and the optic radiations appeared dark before the onset of myelination, and the crus posterior of the internal capsule could be visualized...

  17. Pion absorption in flight on 3He

    International Nuclear Information System (INIS)

    Pion absorption in flight on 3He has been measured in a kinematically complete manner. The experiment was done in the πE1-channel at the Swiss Institute for Nuclear Research, SIN, using π+- and π--beams of 120 and 165 MeV kinetic energy. Two of the emitted particles were measured in coincidence and identified by their time-of-flight/pulseheight relation. The obtained two-dimensional energy representation enabled a separation of the different kinematical regions and exhibited a clear enhancement in the region of quasifree absorption, QFA. (orig./WL)

  18. The ground state energy of 3He droplet in the LOCV framework

    International Nuclear Information System (INIS)

    The (extended) lowest order constrained variational method was used to calculate the ground state energy of liquid helium 3 (3He) droplets at zero temperature. Different types of density distribution profiles, such as the Gaussian, the Quasi-Gaussian and the Woods-Saxon were used. It was shown that at least, on average, near 20 3He atoms are needed to get the bound state for 3He liquid droplet. Depending on the choice of the density profiles and the atomic radius of 3He, the above estimate can increase to 300. Our calculated ground state energy and the number of atoms in liquid 3He droplet were compared with those of Variational Monte Carlo method, Diffusion Monte Carlo method and Density Functional Theory, for which a reasonable agreement was found.

  19. Duoplasmatron source modifications for 3He+ operation

    International Nuclear Information System (INIS)

    A duoplasmatron ion source is used to produce 25 mA of 3He+ with a pulse width of ∼80ms at 360 Hz for acceleration to 10.5 MeV. At this energy, 3He striking water or carbon targets can produce short lived isotopes of 11C, 13N, 15O, and 18F for medical positron emission tomography (PET). A duoplasmatron ion source was chosen originally since it is capable of a sufficient singly charged helium beam with an acceptable gas consumption. Stable long-term operation of the source required a change in the filament material to molybdenum, and a careful understanding of the oxide filament conditioning, operation and geometry. Other improvements, particularly in the electronics, were helpful to increasing the reliability. The source has operated for many months at ∼2.5% duty factor without significant problems and with good stability. We report here the effort that was done to make this source understandable and reliable

  20. Apparent diffusion coefficients in GEC ESTRO target volumes for image guided adaptive brachytherapy of locally advanced cervical cancer

    Energy Technology Data Exchange (ETDEWEB)

    Haack, Soeren (Dept. of Clinical Engineering, Aarhus Univ. Hospital (Denmark)), E-mail: Soeren.haack@stab.rm.dk; Morre Pedersen, Erik (Dept. of Radiology, Aarhus Sygehus, Aarhus Univ. Hospital (Denmark)); Jespersen, Sune N. (Center of Functionally Integrative Neuroscience, Aarhus Univ. Hospital (Denmark)); Kallehauge, Jesper F. (Dept. of Medical Physics, Aarhus Univ. Hospital (Denmark)); Lindegaard, Jacob Christian; Tanderup, Kari (Dept. of Oncology Aarhus Univ. Hospital (Denmark))

    2010-10-15

    Background and purpose. T2 weighted MRI is recommended for image guided adaptive brachytherapy (IGABT) in cervical cancer. Diffusion weighted imaging (DWI) and the derived apparent diffusion coefficient (ADC) may add additional biological information on tumour cell density. The purpose of this study was to evaluate the distribution of the ADC within target volumes as recommended by GEC-ESTRO: Gross Tumour Volume at BT (GTVBT), High-Risk Clinical Tumour Volume (HR-CTV) and Intermediate-Risk Clinical Target Volume (IR-CTV) and to evaluate the change of diffusion between fractions of IGABT. Material and methods. Fifteen patients with locally advanced cervical cancer were examined by MRI before their first (BT1) and second (BT2) fraction of IGABT, resulting in a total of 30 MR examinations including both T2 weighted and DWI sequences. The Apparent Diffusion Coefficient (ADC) was calculated by use of three levels of b-values (0, 600, 1000 s/mm2). ADC maps were constructed and fused with the GEC ESTRO target contours. The mean ADC value within each target volume was calculated. Furthermore, volumes of low diffusion (ADClow) were defined based on an ADC threshold of 1.2 x 10-3 mm2/s, and overlap with target volumes was evaluated. Change of ADC level in target volumes and change of ADClow volume from BT1 to BT2 was also evaluated. Results. The mean ADC was significantly lower in GTVBT than in HR-CTV (p<0.001) which again was significantly lower than in IR-CTV (p<0.001). There was no significant change of the ADClow volume or ADC level within each target structure between BT1 and BT2 (p=0.242). All three GEC-ESTRO volumes contained volumes with low diffusion. The GTVBT contained 37.2% volume of low diffusion, HR-CTV 20.3% and IR-CTV 10.8%. Conclusion. With DWI we were able to find a significant difference in ADC-values for the three different GEC ESTRO targets. This supports the assumption that the target volumes used for dose prescription in IGABT contain tissues with

  1. Coronal Diffusion-weighted Magnetic Resonance Imaging of the Kidney: Agreement with Axial Diffusion-weighted Magnetic Imaging in Terms of Apparent Diffusion Coefficient Values

    Institute of Scientific and Technical Information of China (English)

    Hai-Yi Wang; Jia Wang; Ye-Huan Tang; Hui-Yi Ye; Lin Ma

    2015-01-01

    Background:Coronal diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient (ADC) values have gradually become applied (following conventional axial DW-MRI) in the renal analysis.To explore whether data obtained using coronal DW-MRI are comparable with those derived using axial DW-MRI,this preliminary study sought to assess the agreement in renal ADC values between coronal DW-MRI and axial DW-MRI.Methods:Thirty-four healthy volunteers were enrolled in the study; written consents were obtained.All subjects underwent respiratory-triggered axial and coronal DW-MRI using a 1.5-MR system with b values of 0 and 800 s/mm2.The signal-to-noise ratios (SNRs) of the two DW-MRI sequences were measured and statistically compared using the paired t-test.The extent of agreement of ADC values of the upper pole,mid-pole,and lower pole of the kidney; the mean ADC values of the left kidney and right kidney; and the mean ADC values of the bilateral kidneys were evaluated via calculation of intraclass correlation coefficients (ICCs) or Bland-Altman method between the two DW-MRI sequences.Results:The SNR of coronal DW-MR images was statistically inferior to that of axial DW-MR images (P < 0.001).The ICCs of the ADC values of each region of interest,and the mean ADC values of bilateral kidneys,between the two sequences,were greater than 0.5,and the mean ADCs of the bilateral kidneys demonstrated the highest ICC (0.869; 95% confidence interval:0.739-0.935).In addition,94.1% (32/34),94.1% (32/34),and 97.1% (31/34) of the ADC bias was inside the limits of agreement in terms of the mean ADC values of the left kidneys,right kidneys,and bilateral kidneys when coronal and axial DWI-MRI were compared.Conclusions:ADC values derived using coronal DW-MRI exhibited moderate-to-good agreement to those of axial DW-MRI,rendering the former an additional useful DW-MRI method,and causing the ADC values derived using the two types of DW-MRI to be comparable.

  2. Measurement of the apparent diffusion coefficient in paediatric mitochondrial encephalopathy cases and a comparison of parenchymal changes associated with the disease using follow-up diffusion coefficient measurements

    Energy Technology Data Exchange (ETDEWEB)

    Uysal, Fatma, E-mail: afatmauysal@gmail.com [Dokuz Eylül University, Department of Pediatric Radiology, Izmir (Turkey); Çakmakçı, Handan, E-mail: handan.cakmakci@deu.edu.tr [Dokuz Eylül University, Department of Pediatric Radiology, Izmir (Turkey); Yiş, Uluç, E-mail: ulucyis@deu.edu.tr [Dokuz Eylül University, Department of Pediatric Neurology, Izmir (Turkey); Ellidokuz, Hülya, E-mail: hulyaellidokuz@deu.edu.tr [Dokuz Eylül University, Department of Medical Statistics, Izmir (Turkey); Hız, Ayşe Semra, E-mail: aysesemrahiz@deu.edu.tr [Dokuz Eylül University, Department of Pediatric Neurology, Izmir (Turkey)

    2014-01-15

    Objectives: To reveal the contribution of MRI and diffusion-weighted imaging (DWI) to the diagnosis of mitochondrial encephalopathy (ME) and to evaluate the parenchymal changes associated with this disease in the involved parenchymal areas using the apparent diffusion coefficient (ADC) parameter. Methods: Ten patients who had undergone MRI and DWI analysis with a pre-diagnosis of neurometabolic disease, and who were subsequently diagnosed with ME in laboratory and/or genetic studies, were included in our study. ADC values were compared with a control group composed of 20 patients of similar age with normal brains. Evaluations involved measurements made in 20 different areas determined on the ADC map. The dominance or contribution of ADC coefficient measurements to the conventional sequences was compared with the controls. Results: In the first examination, an increase in both diffusion and ADC values was detected in six cases and diffusion restriction and a decrease in ADC values in three patients. While an increase in both diffusion and ADC values was demonstrated in four cases, there was diffusion restriction and a decrease in ADC values in three cases in the control examinations. Conclusions: DWI provides information that complements conventional MRI sequences in the diagnosis of ME.

  3. Molecular Dynamics and Monte Carlo simulations resolve apparent diffusion rate differences for proteins confined in nanochannels

    Energy Technology Data Exchange (ETDEWEB)

    Tringe, J.W., E-mail: tringe2@llnl.gov [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA (United States); Ileri, N. [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA (United States); Department of Chemical Engineering & Materials Science, University of California, Davis, CA (United States); Levie, H.W. [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA (United States); Stroeve, P.; Ustach, V.; Faller, R. [Department of Chemical Engineering & Materials Science, University of California, Davis, CA (United States); Renaud, P. [Swiss Federal Institute of Technology, Lausanne, (EPFL) (Switzerland)

    2015-08-18

    Highlights: • WGA proteins in nanochannels modeled by Molecular Dynamics and Monte Carlo. • Protein surface coverage characterized by atomic force microscopy. • Models indicate transport characteristics depend strongly on surface coverage. • Results resolve of a four orders of magnitude difference in diffusion coefficient values. - Abstract: We use Molecular Dynamics and Monte Carlo simulations to examine molecular transport phenomena in nanochannels, explaining four orders of magnitude difference in wheat germ agglutinin (WGA) protein diffusion rates observed by fluorescence correlation spectroscopy (FCS) and by direct imaging of fluorescently-labeled proteins. We first use the ESPResSo Molecular Dynamics code to estimate the surface transport distance for neutral and charged proteins. We then employ a Monte Carlo model to calculate the paths of protein molecules on surfaces and in the bulk liquid transport medium. Our results show that the transport characteristics depend strongly on the degree of molecular surface coverage. Atomic force microscope characterization of surfaces exposed to WGA proteins for 1000 s show large protein aggregates consistent with the predicted coverage. These calculations and experiments provide useful insight into the details of molecular motion in confined geometries.

  4. Formation of 3He droplets in dilute 3He-4He solid solutions

    Science.gov (United States)

    Huan, Chao; Candela, Don; Kim, Sung; Yin, Liang; Xia, Jiang-Sheng; Sullivan, Neil

    2015-03-01

    We review the different stages of the formation of 3He droplets in dilute solid 3He-4He solutions. The studies are interesting because the phase separation in isotopic helium mixtures is a first-order transition with a conserved order parameter. The rate of growth of the droplets as observed in NMR studies is compared with the rates expected for homogeneous nucleation followed by a period of coarsening known as Ostwald ripening. Work suported by the National Science Foundation - DMR-1303599 and DMR- 1157490 (National High Magnetic Field Laboratory).

  5. Analysis of the utility of diffusion-weighted MRI and apparent diffusion coefficient values in distinguishing central nervous system toxoplasmosis from lymphoma

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, Paul C.; Donovan Post, M. Judith; Bruce-Gregorios, Jocelyn [University of Miami, Jackson Memorial Hospital, Miami, FL (United States); Oschatz, Elizabeth; Stadler, Alfred; Thurnher, Majda M. [Medical University of Vienna, Department of Radiology Neuroradiology Section, Vienna (Austria)

    2006-10-15

    Toxoplasmosis and lymphoma are common lesions of the central nervous system in patients with AIDS. It is often difficult to distinguish between these lesions both clinically and radiographically. Previous research has demonstrated restricted diffusion within cerebral lymphomas and bacterial abscesses. However, little work has been done to evaluate the diffusion characteristics of toxoplasmosis lesions. This study was designed to explore further the utility of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps and values in making the distinction between toxoplasmosis and lymphoma. The magnetic resonance imaging (MRI) studies of 36 patients, including 22 with toxoplasmosis (all of whom had AIDS) and 14 with lymphoma (8 of whom had AIDS), at two institutions were reviewed retrospectively. The characteristics of the lesions on DWI were evaluated, and the ADC ratios of the lesions were calculated and compared. There was significant overlap of the ADC ratios of toxoplasma and lymphoma, most notably in the intermediate (1.0-1.6) range. There was variability in ADC ratios even among different lesions in the same patient. In only a minority of the lymphoma patients were the ADC ratios low enough to suggest the correct diagnosis. Our study showed that toxoplasmosis exhibits a wide spectrum of diffusion characteristics with ADC ratios which have significant overlap with those of lymphoma. Therefore, in the majority of patients, ADC ratios are not definitive in making the distinction between toxoplasmosis and lymphoma. (orig.)

  6. The origin of a large apparent tortuosity factor for the Knudsen diffusion inside monoliths of a samaria-alumina aerogel catalyst: a diffusion NMR study.

    Science.gov (United States)

    Mueller, R; Zhang, S; Klink, M; Bäumer, M; Vasenkov, S

    2015-11-01

    Pulsed field gradient (PFG) NMR was applied to measure tortuosity factors for carbon dioxide diffusion in the Knudsen and gas regimes inside monoliths of a samaria-alumina aerogel catalyst, a high porosity material containing micropores in addition to meso- and macropores. The apparent tortuosity factor obtained from PFG NMR measurements for the Knudsen diffusion in the meso- and macropores of the catalyst has an unexpectedly large value of approximately 6 if carbon dioxide adsorption in the micropores and other types of surface adsorption sites of the catalyst is ignored. At the same time, the corresponding apparent tortuosity factor in the gas regime was found to be around 2. Application of a proposed model which describes fast molecular exchange between the surface adsorption sites and the main pore volume of the catalyst yields corrected tortuosity factors which depend only on the pore system geometry. Using this model, the corrected tortuosity factors were found to be around 2 for both diffusion regimes, in agreement with the expectations based on a high porosity of the studied catalyst.

  7. Gene interference regulates aquaporin-4 expression in swollen tissue of rats with cerebral ischemic edema Correlation with variation in apparent diffusion coefficient

    Institute of Scientific and Technical Information of China (English)

    Hui Hu; Hong Lu; Zhanping He; Xiangjun Han; Jing Chen; Rong Tu

    2012-01-01

    To investigate the effects of mRNA interference on aquaporin-4 expression in swollen tissue of rats with ischemic cerebral edema, and diagnose the significance of diffusion-weighted MRI, we injected 5 μL shRNA- aquaporin-4 (control group) or siRNA- aquaporin-4 solution (1:800) (RNA interference group) into the rat right basal ganglia immediately before occlusion of the middle cerebral artery. At 0.25 hours after occlusion of the middle cerebral artery, diffusion-weighted MRI displayed a high signal; within 2 hours, the relative apparent diffusion coefficient decreased markedly, aquaporin-4 expression increased rapidly, and intracellular edema was obviously aggravated; at 4 and 6 hours, the relative apparent diffusion coefficient slowly returned to control levels, aquaporin-4 expression slightly increased, and angioedema was observed. In the RNA interference group, during 0.25- 6 hours after injection of siRNA- aquaporin-4 solution, the relative apparent diffusion coefficient slightly fluctuated and aquaporin-4 expression was upregulated; during 0.5-4 hours, the relative apparent diffusion coefficient was significantly higher, while aquaporin-4 expression was significantly lower when compared with the control group, and intracellular edema was markedly reduced; at 0.25 and 6 hours, the relative apparent diffusion coefficient and aquaporin-4 expression were similar when compared with the control group; obvious angioedema remained at 6 hours. Pearson's correlation test results showed that aquaporin-4 expression was negatively correlated with the apparent diffusion coefficient (r = -0.806, P < 0.01). These findings suggest that upregulated aquaporin-4 expression is likely to be the main molecular mechanism of intracellular edema and may be the molecular basis for decreased relative apparent diffusion coefficient. Aquaporin-4 gene interference can effectively inhibit the upregulation of aquaporin-4 expression during the stage of intracellular edema with time

  8. Automatic Detection and Quantification of Acute Cerebral Infarct by Fuzzy Clustering and Histographic Characterization on Diffusion Weighted MR Imaging and Apparent Diffusion Coefficient Map

    Directory of Open Access Journals (Sweden)

    Jang-Zern Tsai

    2014-01-01

    Full Text Available Determination of the volumes of acute cerebral infarct in the magnetic resonance imaging harbors prognostic values. However, semiautomatic method of segmentation is time-consuming and with high interrater variability. Using diffusion weighted imaging and apparent diffusion coefficient map from patients with acute infarction in 10 days, we aimed to develop a fully automatic algorithm to measure infarct volume. It includes an unsupervised classification with fuzzy C-means clustering determination of the histographic distribution, defining self-adjusted intensity thresholds. The proposed method attained high agreement with the semiautomatic method, with similarity index 89.9 ± 6.5%, in detecting cerebral infarct lesions from 22 acute stroke patients. We demonstrated the accuracy of the proposed computer-assisted prompt segmentation method, which appeared promising to replace the laborious, time-consuming, and operator-dependent semiautomatic segmentation.

  9. Relative apparent diffusion coefficient: a promising tool to differentiate metastatic from benign lymph nodes in animal models

    Institute of Scientific and Technical Information of China (English)

    XING Wei; SHENG Jing; CHEN Jie; TIAN Jian-ming; BI Heng-liang

    2011-01-01

    Background Diffusion-weighted imaging has been widely used to differentiate the character of lymphadenopathy. But there are significant differences between prior studies. The aim of the study was to compare the benefit of apparent diffusion coefficient (ADC) and rADC in the differentiation of metastatic and benign lymph nodes in a rabbit model.Methods Two observers independently measured ADCs in quadriceps of every rabbit on diffusion-weighted images with different sizes of regions of interest (ROI). The appropriate ROI for rADC was determined using the interobserver coefficient. rADC was calculated by ADClesion/ADCreference site. Receiver operating characteristics (ROC) analysis was performed to compare the diagnostic value of the ADC values and rADC values in differentiating metastatic from benign lymph nodes.Results When the ROIs included five pixels, the ICC was 0.816, indicating a good interobserver agreement. The differences of ADC and rADC values between metastatic and benign lymph nodes were both statistically significant. The area under the ROC curve was greater for the rADC than for the ADC. With the rADC criteria of 0.640, the sensitivity and specificity for differentiating metastatic from benign lymph nodes were 93% and 90%, respectively.Conclusion As a reference site, muscles reveal a good repeatability using a small ROI and the rADC may improve diagnostic accuracy for detecting metastatic nodes in animal models.

  10. Assessment of Apparent Diffusion Coefficient Values as Predictor of Aggressiveness in Peripheral Zone Prostate Cancer: Comparison with Gleason Score

    International Nuclear Information System (INIS)

    Purpose. To determine association between apparent diffusion coefficient value on diffusion-weighted imaging and Gleason score in patients with prostate cancer. Methods. This retrospective case series was conducted at Radiology Department of Aga Khan University between June 2009 and June 2011. 28 patients with biopsy-proven prostate cancer were included who underwent ultrasound guided sextant prostate biopsy and MRI. MRI images were analyzed on diagnostic console and regions of interest were drawn. Data were entered and analyzed on SPSS 20.0. ADC values were compared with Gleason score using one-way ANOVA test. Results. In 28 patients, 168 quadrants were biopsied and 106 quadrants were positive for malignancy. 89 lesions with proven malignancy showed diffusion restriction. The mean ADC value for disease with a Gleason score of 6 was 935 mm2/s (SD = 248.4 mm2/s); Gleason score of 7 was 837 mm2/s (SD = 208.5 mm2/s); Gleason score of 8 was 614 mm2/s (SD = 108 mm2/s); and Gleason score of 9 was 571 mm2/s (SD = 82 mm2/s). Inverse relationship was observed between Gleason score and mean ADC values. Conclusion. DWI and specifically quantitative ADC values may help differentiate between low-risk (Gleason score, 6), intermediate-risk (Gleason score, 7), and high-risk (Gleason score 8 and 9) prostate cancers, indirectly determining the aggressiveness of the disease

  11. Critical opalescent light scattering from 3He

    International Nuclear Information System (INIS)

    The experimental work reported in this paper was stimulated by the widespread revival of interest in critical phenomena. In this experiment the authors measured the intensity of light scattered from 3He while very slowly warming the sample at constant pressure through the critical region. About 0.3 mW from a helium-neon laser was incident on the cell; cell temperature was recorded continuously, as was the light scattered at 45 degrees and 135 degrees. A succession of passes was made at different pressures, all less than c, so these results apply only in the one-phase region above the critical point. Sample density at the beginning of a pass began at ρ > c, then decreased as the sample warmed to ρ c. The scattering intensity increased monotonically as the molar density decreased toward the critical density, then decreased monotonically thereafter on that isobaric pass. The scattering maximum on each pass occurred at the temperature max where the isothermal compressibility was a maximum. The asymptotic divergence of T was evaluated along the locus of these maxima

  12. {eta} photoproduction off {sup 3}He

    Energy Technology Data Exchange (ETDEWEB)

    Witthauer, Lilian [Department of Physics, University Basel (Switzerland)

    2010-07-01

    Quark models predict many more states in the excitation spectrum of the nucleon than observed in experiments. Most previous experiments investigating the excitation spectrum of nucleons are based on elastic scattering of charged pions. This makes it probable that the data is biased against states that couple only weakly to N{pi}. Hence, one can study different excitation mechanisms and channels as the photoproduction of mesons via excitation of nucleon resonances. Measurements at ELSA in Bonn investigated the quasi-free {eta} photoproduction off the neutron (I. Jaegle et al., Phys. Rev. Lett 100 (2008) 252002). The resulting cross section shows a narrow structure at W=1.68 GeV with a width smaller than 60 MeV. This structure is only visible in the cross section on the neutron and not in that on the proton. Experiments of the GRAAL collaboration (V.Kuznetsov et al., arXiv:hep-ex/0606065v2) and LNS-Sendai (F. Miyahara et al., Prog. Theor. Phys. Suppl. 168 (2007) 90) showed the same effect in quasi-free photoproduction off the deuteron. In order to exclude any possibility that the structure could arise from nuclear effects (re-scattering of mesons, final state interaction) we have studied it for a nucleon system with different momentum distribution and different neutron/proton ratio, namely {sup 3}He. Preliminary results for the quasi-free {eta} cross section obtained in coincidence with recoil nucleons will be discussed.

  13. Possibility of optically pumped 3He as an internal target

    International Nuclear Information System (INIS)

    A number of techniques can be listed for obtaining polarized 3He nuclei. This paper focuses only on direct optical pumping of 3He(3S1) with collisional transfer to 3He. A comprehensive review is not attempted. The basic aspects of the method are presented followed by a discussion of only the most recent work

  14. Can measurement of apparent diffusion coefficient before treatment predict the response to uterine artery embolization for adenomyosis?

    Energy Technology Data Exchange (ETDEWEB)

    Park, Yaewon; Kim, Man Deuk; Jung, Dae Chul; Lee, Shin Jae; Kim, Gyoungmin; Park, Sung Il; Won, Jong Yun; Lee, Do Yun [Yonsei University College of Medicine, Department of Radiology, Severance Hospital, Seoul (Korea, Republic of)

    2015-05-01

    To determine the usefulness of the apparent diffusion coefficient (ADC) in predicting response to uterine artery embolization (UAE) for symptomatic adenomyosis. A prospective study was performed on 25 patients who underwent diffusion-weighted (DW) magnetic resonance imaging (MRI) before UAE between June 2011 and December 2012. All patients underwent 3-month follow-up MRI after UAE using non-spherical polyvinyl alcohol (PVA) particles ranging from 150 to 500 μm. Quantitative measurement of the ADC was performed for each adenomyosis. Complete response and incomplete response were defined as ≥90 % or <90 %, respectively, of the non-perfusion area with adenomyosis at the follow-up MRI. The ADC values were compared between patients who achieved complete or incomplete response which was assessed according to the MRI findings after UAE. Nineteen patients showed complete response, and six showed incomplete response. The ADC value ranged from 0.842 to 1.346 x 10{sup -3} mm{sup 2}/s (mean 1.075 ± 0.117). The mean ADC was 1.043 ± 0.237 in the complete response group and 1.176 ± 0.429 in the incomplete response group (0.012). Using a threshold of <1.147 x 10{sup -3} mm{sup 2}/s, the sensitivity and specificity of the ADC to predict success after UAE were 83.3 % and 84.2 %. The ADC of adenomyosis may potentially predict a successful response to UAE for adenomyosis. (orig.)

  15. Acoustic and optical investigations of superfluid 3He. Doctoral thesis

    Energy Technology Data Exchange (ETDEWEB)

    Manninen, A.

    1993-06-15

    The thesis is an experimental survey of properties of rotating and stationary superfluid (3)He. Two techniques, acoustics and optics, were used. Ultrasound, together with NMR, has provided most of the present experimental knowledge about the superfluid phases of (3)He. The author applied acoustics for the first time to study rotating (3)He. The main result was the discovery of a new vortex in (3)He-A when the magnetic field is low. New phenomena were observed in stationary (3)He as well. Most importantly, one of the collective modes, the real squashing (rsq) mode, of (3)He-B could be excited by means of two-phonon absorption. Superfluid (3)He was studied optically for the first time. No one has previously seen (3)He in the superfluid state. The principal achievement was developing techniques which facilitate optical experiments at temperatures below 1 mK, required to study superfluid (3)He. Optical fibers were used to transmit light between room temperature and the cold parts of the cryostat. Before these investigations, photography had not been done below 10 mK. The usefulness of optics as a proble of the superfluid phases of (3)He was demonstrated by studying the macroscopic shape of the free surface of rotating (3)He-B. The classical parabolic meniscus was observed, which is indicative of the equilibrium density of vortices.

  16. Efficiency of apparent diffusion coefficients in differentiation of colorectal tumor recurrences and posttherapeutical soft-tissue changes

    Energy Technology Data Exchange (ETDEWEB)

    Nural, Mehmet Selim, E-mail: msnural@omu.edu.tr [Department of Radiology, Medical Faculty, Ondokuz Mayis University, 55139 Samsun (Turkey); Danaci, Murat, E-mail: danacim55@yahoo.com [Department of Radiology, Medical Faculty, Ondokuz Mayis University, 55139 Samsun (Turkey); Soyucok, Ahmet, E-mail: soyucokac@hotmail.com [Department of Radiology, Medical Faculty, Ondokuz Mayis University, 55139 Samsun (Turkey); Okumus, Nilgun Ozbek, E-mail: 2121@omu.edu.tr [Department of Radiation Oncology, Medical Faculty, Ondokuz Mayis University, 55139 Samsun (Turkey)

    2013-10-01

    Objective: To evaluate effectiveness of apparent diffusion coefficient (ADC) values measured by diffusion-weighted magnetic resonance imaging (DW-MRI) in differentiation of colorectal tumor recurrences and posttherapeutical soft tissue changes. Methods: For this prospective study, 30 patients (22 males, 8 females; age range 30–81 years; mean age 61 ± 12 years) who underwent surgery for colorectal tumors and had a mass detected by computed tomography (CT) and/or MRI during follow-up examinations were divided into 2 groups [17 patients (Group 1) with recurrence and 13 patients (Group 2) with benign fibrosis/granulation tissue]. Final diagnoses were based on histopathological examination in 14 patients and clinical follow-up at least 6 months in the remaining 16. In the latter, the diagnosis of recurrence was made in cases in which the lesion was larger on follow-up CT and MRI; recurrence was ruled out in cases of stable or shrinking lesions without any increase in tumor markers. DW-MRI was performed in the axial plane, for two different b values (b = 0 and 800 s/mm{sup 2}). The mean apparent diffusion coefficient (ADC) values were measured by manual delineation of regions of interest on ADC maps. Results: The median ADC values were 1.07 × 10{sup −3} mm/s{sup 2} (min: 0.82, max: 2.05) and 1.91 × 10{sup −3} mm/s{sup 2} (min: 1.51, max: 2.22) in Groups 1 and 2, respectively. A statistically significant difference was detected between the two groups (P < 0.001). When the threshold value used to determine whether the lesions recurred was 1.48 × 10{sup −3} mm/s{sup 2} based on ROC analysis, the sensitivity was 82% and the specificity was 100%. There were three patients with a false-negative diagnosis, and the primary histopathological diagnosis of all was mucinous adenocarcinoma. Conclusions: Because recurrences in mucinous adenocarcinomas have high ADC values, they may show overlap with benign lesions. In the detection of the local recurrence of colorectal

  17. Initial Experience of 3-Tesla Apparent Diffusion Coefficient Values in Characterizing Squamous Cell Carcinomas of the Head and Neck

    International Nuclear Information System (INIS)

    Background: With the increased clinical use of 3-Tesla (3T) magnets, it becomes important to identify the potential applications of advanced magnetic resonance (MR) imaging techniques such as diffusion-weighted imaging in head and neck pathologies. Purpose: To establish the 3T apparent diffusion coefficient (ADC) values for normal neck structures, and to examine the utility of ADC values in distinguishing head and neck squamous cell carcinomas (HNSCC) from normal neck anatomy. Material and Methods: 3T diffusion-weighted imaging was performed on 10 normal volunteers and 10 patients with known HNSCC. In the volunteers, mean ADC was calculated in the parotid gland, submandibular gland, base of the tongue, pterygoid muscle, masseter muscle, paraspinal muscles, true vocal cord, thyroid gland, thyroid cartilage, cricoid cartilage, and lymph nodes. The mean tumor ADC value was calculated from the 10 patients with HNSCC and compared with the normal ADC values from various neck structures. Results: The mean ADC value measured in the HNSCC was 1.101 (±0.214)x10-3mm2/s. This was significantly lower than ADC values of paraspinal muscles, pterygoid muscle, masseter muscle, thyroid gland, and base of the tongue (P=0.0006, 0.0002, 0.0001, 0.001, and 0.002, respectively). The tumor ADC values were not significantly different from ADC values of parotid and submandibular glands (P=0.057 and 0.14, respectively). Conclusion: 3T ADC values show potential for distinguishing HNSCC from normal extracranial head and neck structures

  18. Apparent diffusion coefficient vale of the brain in patients with Gaucher's disease type II and type III

    Energy Technology Data Exchange (ETDEWEB)

    Abdel Razek, Ahmed Abdel Khalek; Abd El-Gaber, Nahed [Mansoura Faculty of Medicine, Department of Diagnostic Radiology, Mansoura (Egypt); Abdalla, Ahmed; Fathy, Abeer [Mansoura Faculty of Medicine, Department of Pediatric, Mansoura (Egypt); Azab, Ahmed [Mansoura Faculty of Medicine, Department of Neurology, Mansoura (Egypt); Rahman, Ashraf Abdel [Radiology Unit of Pediatric Hospital, Mansoura (Egypt)

    2009-11-15

    The aim of this work is to assess the usefulness of apparent diffusion coefficient (ADC) value of the brain for diagnosis of patients with Gaucher's disease type II and type III. Prospective study was conducted upon 13 patients (nine boys and four girls aged 8 months-14 years: mean 6.1 years) with Gaucher's disease type II and III and for age-matched control group (n = 13). Diffusion-weighted magnetic resonance imaging using a single-shot echo-planar imaging with a diffusion-weighted factor b of 0, 500, and 1,000 s/mm{sup 2} was done for all patients and volunteers. The ADC value was calculated in ten regions of the brain parenchyma and correlated with genotyping. There was significantly lower ADC value of the cortical frontal (P = 0.003), cortical temporal (P = 0.04), frontal subcortical white matter (P = 0.02), corticospinal tract (P = 0.001), cerebellum (P = 0.001), medulla (P = 0.002), and midbrain (P = 0.02) between patients and volunteers. There was significant difference in the ADC value of the frontal and temporal gray matter (P = 0.04 and 0.05, respectively) between patients with heterozygous and homozygous gene mutation. We concluded that ADC value is a new promising quantitative imaging parameter that can be used for the detection of brain abnormalities in patients with Gaucher's disease type II and type III and has a correlation with genotyping. (orig.)

  19. Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study.

    Directory of Open Access Journals (Sweden)

    Matthew D Blackledge

    Full Text Available We describe our semi-automatic segmentation of whole-body diffusion-weighted MRI (WBDWI using a Markov random field (MRF model to derive tumor total diffusion volume (tDV and associated global apparent diffusion coefficient (gADC; and demonstrate the feasibility of using these indices for assessing tumor burden and response to treatment in patients with bone metastases. WBDWI was performed on eleven patients diagnosed with bone metastases from breast and prostate cancers before and after anti-cancer therapies. Semi-automatic segmentation incorporating a MRF model was performed in all patients below the C4 vertebra by an experienced radiologist with over eight years of clinical experience in body DWI. Changes in tDV and gADC distributions were compared with overall response determined by all imaging, tumor markers and clinical findings at serial follow up. The segmentation technique was possible in all patients although erroneous volumes of interest were generated in one patient because of poor fat suppression in the pelvis, requiring manual correction. Responding patients showed a larger increase in gADC (median change = +0.18, range = -0.07 to +0.78 × 10(-3 mm2/s after treatment compared to non-responding patients (median change = -0.02, range = -0.10 to +0.05 × 10(-3 mm2/s, p = 0.05, Mann-Whitney test, whereas non-responding patients showed a significantly larger increase in tDV (median change = +26%, range = +3 to +284% compared to responding patients (median change = -50%, range = -85 to +27%, p = 0.02, Mann-Whitney test. Semi-automatic segmentation of WBDWI is feasible for metastatic bone disease in this pilot cohort of 11 patients, and could be used to quantify tumor total diffusion volume and median global ADC for assessing response to treatment.

  20. Comparative Analysis of Signal Intensity and Apparent Diffusion Coefficient at Varying b-values in the Brain : Diffusion Weighted-Echo Planar Image (T2 and FLAIR) Sequence

    International Nuclear Information System (INIS)

    Diffusion-weighted imaging (DWI) has been demonstrated to be a practical method for the diagnosis of various brain diseases such as acute infarction, brain tumor, and white matter disease. In this study, we used two techniques to examine the average signal intensity (SI) and apparent diffusion coefficient (ADC) of the brains of patients who ranged in age from 10 to 60 years. Our results indicated that the average SI was the highest in amygdala (as derived from DWI), whereas that in the cerebrospinal fluid was the lowest. The average ADC was the highest in the cerebrospinal fluid, whereas the lowest measurement was derived from the pons. The average SI and ADC were higher in T2-DW-EPI than in FLAIR-DW-EPI. The higher the b-value, the smaller the average difference in both imaging techniques; the lower the b-value, the greater the average difference. Also, comparative analysis of the brains of patients who had experienced cerebral infarction showed no distinct lesion in the general MR image over time. However, there was a high SI in apparent weighted images. Analysis of other brain diseases (e.g., bleeding, acute, subacute, chronic infarction) indicated SI variance in accordance with characteristics of the two techniques. The higher the SI, the lower the ADC. Taken together, the value of SI and ADC in accordance with frequently occurring areas and various brain disease varies based on the b-value and imaging technique. Because they provide additional useful information in the diagnosis and treatment of patients with various brain diseases through signal recognition, the proper imaging technique and b-value are important for the detection and interpretation of subacute stroke and other brain diseases.

  1. Apparent diffusion coefficient values of diffusion-weighted imaging for distinguishing focal pulmonary lesions and characterizing the subtype of lung cancer: a meta-analysis

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Guohua; Jia, Zhiyun; Deng, Houfu [Sichuan University, Department of Nuclear Medicine, West China Hospital, Chengdu, Sichuan (China)

    2016-02-15

    The potential performance of apparent diffusion coefficient (ADC) values for distinguishing malignant and benign pulmonary lesions, further characterizing the subtype of lung cancer was assessed. PubMed, EMBASE, Cochrane Library, EBSCO, and three Chinese databases were searched to identify eligible studies on diffusion-weighted imaging (DWI) of focal pulmonary lesions. ADC values of malignant and benign lesions were extracted by lesion type and statistically pooled based on a linear mixed model. Further analysis for subtype of lung cancer was also performed. The methodological quality was assessed using the quality assessment of diagnostic accuracy studies tool. Thirty-four articles involving 2086 patients were included. Malignant pulmonary lesions have significantly lower ADC values than benign lesions [1.21 (95 % CI, 1.19-1.22) mm{sup 2}/s vs. 1.76 (95 % CI, 1.72-1.80) mm{sup 2}/s; P < 0.05]. There is a significant difference between ADC values of small cell lung cancer and non-small cell lung cancer (P < 0.05), while the differences were not significant among histological subtypes of lung cancer. The methodological quality was relatively high, and the data points from Begg's test indicated that there was probably no obvious publication bias. The ADC value is helpful for distinguishing malignant and benign pulmonary lesions and provides a promising method for differentiation of SCLC from NSCLC. (orig.)

  2. Apparent diffusion coefficient values of diffusion-weighted imaging for distinguishing focal pulmonary lesions and characterizing the subtype of lung cancer: a meta-analysis

    International Nuclear Information System (INIS)

    The potential performance of apparent diffusion coefficient (ADC) values for distinguishing malignant and benign pulmonary lesions, further characterizing the subtype of lung cancer was assessed. PubMed, EMBASE, Cochrane Library, EBSCO, and three Chinese databases were searched to identify eligible studies on diffusion-weighted imaging (DWI) of focal pulmonary lesions. ADC values of malignant and benign lesions were extracted by lesion type and statistically pooled based on a linear mixed model. Further analysis for subtype of lung cancer was also performed. The methodological quality was assessed using the quality assessment of diagnostic accuracy studies tool. Thirty-four articles involving 2086 patients were included. Malignant pulmonary lesions have significantly lower ADC values than benign lesions [1.21 (95 % CI, 1.19-1.22) mm2/s vs. 1.76 (95 % CI, 1.72-1.80) mm2/s; P < 0.05]. There is a significant difference between ADC values of small cell lung cancer and non-small cell lung cancer (P < 0.05), while the differences were not significant among histological subtypes of lung cancer. The methodological quality was relatively high, and the data points from Begg's test indicated that there was probably no obvious publication bias. The ADC value is helpful for distinguishing malignant and benign pulmonary lesions and provides a promising method for differentiation of SCLC from NSCLC. (orig.)

  3. Role of diffusion-weighted imaging, apparent diffusion coefficient and correlation with hepatobiliary phase findings in the differentiation of hepatocellular carcinoma from dysplastic nodules in cirrhotic liver

    Energy Technology Data Exchange (ETDEWEB)

    Inchingolo, Riccardo; De Gaetano, Anna Maria; Curione, Davide; Ciresa, Marzia; Bonomo, Lorenzo [Catholic University of the Sacred Heart, Department of Bioimaging and Radiological Sciences, Institute of Radiology, ' ' Agostino Gemelli' ' Hospital, Rome (Italy); Miele, Luca; Pompili, Maurizio [Catholic University of the Sacred Heart, Department of Internal Medicine, ' ' Agostino Gemelli' ' Hospital, Rome (Italy); Vecchio, Fabio Maria [Catholic University of the Sacred Heart, Department of Anatomo-Pathology, ' ' Agostino Gemelli' ' Hospital, Rome (Italy); Giuliante, Felice [Catholic University of the Sacred Heart, Department of Surgery, ' ' Agostino Gemelli' ' Hospital, Rome (Italy)

    2015-04-01

    To investigate the utility of diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) and the correlation with hepatobiliary phase (delayed phase imaging, DPI) findings in the differentiation of cirrhotic hepatocellular nodules. Forty-three patients with 53 pathology-proven nodules (29 hepatocellular carcinomas (HCCs), 13 high-grade (HGDNs) and 11 low-grade dysplastic nodules (LGDNs); mean size 2.17 cm, range 1-4 cm), who underwent liver MRI with DWI and DPI sequences, were retrospectively reviewed. Lesions were classified as hypointense, isointense, or hyperintense relative to the adjacent liver parenchyma. ADC of each nodule, of the surrounding parenchyma, and lesion-to-liver ratio were calculated. Hyperintensity versus iso/hypointensity on DWI, hypointensity versus iso/hyperintensity on DPI, and the mean lesion-to-liver ratio showed a statistically significant difference both between HCCs versus DNs and between ''HCCs + HGDNs'' versus LGDNs (p < 0.05); sensitivity, specificity, and accuracy for the diagnosis of ''HCCs + HGDNs'' were 96.8 %, 100 %, 97.4 % respectively when combining hyperintensity on DWI and hypointensity on DPI, and 90.9 %, 81.0 %, 83.6 % respectively when lesion-to-liver ratio was <0.95. Hyperintensity on DWI, especially in association with hypointensity on DPI, and low lesion-to-liver ratios should raise the suspicion of HCC, or at least of HGDN, thus helping the characterization of atypically enhancing lesions. (orig.)

  4. Using the apparent diffusion coefficient to identifying MGMT promoter methylation status early in glioblastoma: importance of analytical method

    Energy Technology Data Exchange (ETDEWEB)

    Rundle-Thiele, Dayle [Centre for Clinical Research, University of Queensland, Brisbane, Queensland (Australia); Day, Bryan; Stringer, Brett [Brain Cancer Research Unit, Queensland Institute of Medical Research, Brisbane, Queensland (Australia); Fay, Michael [Department of Radiation Oncology, Royal Brisbane and Women' s Hospital, Brisbane, Queensland (Australia); Martin, Jennifer [Discipline of Clinical Pharmacology, School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales (Australia); Jeffree, Rosalind L [Department of Neurosurgery, Royal Brisbane and Women' s Hospital, Brisbane, Queensland (Australia); Thomas, Paul [Queensland PET Service, Royal Brisbane and Women' s Hospital, Brisbane, Queensland (Australia); Bell, Christopher [Centre for Clinical Research, University of Queensland, Brisbane, Queensland (Australia); Salvado, Olivier [CSIRO Digital Productivity Flagship, CSIRO, Herston, Queensland (Australia); Gal, Yaniv [Centre for Medical Diagnostic Technologies in Queensland, University of Queensland, Brisbane, Queensland (Australia); Coulthard, Alan [Discipline of Medical Imaging, University of Queensland, St Lucia, Queensland (Australia); Department of Medical Imaging, Royal Brisbane and Women' s Hospital, Brisbane, Queensland (Australia); Crozier, Stuart [Centre for Medical Diagnostic Technologies in Queensland, University of Queensland, Brisbane, Queensland (Australia); Rose, Stephen, E-mail: stephen.rose@csiro.au [CSIRO Digital Productivity Flagship, CSIRO, Herston, Queensland (Australia); Centre for Clinical Research, University of Queensland, Brisbane, Queensland (Australia)

    2015-06-15

    Accurate knowledge of O{sup 6}-methylguanine methyltransferase (MGMT) gene promoter subtype in patients with glioblastoma (GBM) is important for treatment. However, this test is not always available. Pre-operative diffusion MRI (dMRI) can be used to probe tumour biology using the apparent diffusion coefficient (ADC); however, its ability to act as a surrogate to predict MGMT status has shown mixed results. We investigated whether this was due to variations in the method used to analyse ADC. We undertook a retrospective study of 32 patients with GBM who had MGMT status measured. Matching pre-operative MRI data were used to calculate the ADC within contrast enhancing regions of tumour. The relationship between ADC and MGMT was examined using two published ADC methods. A strong trend between a measure of ‘minimum ADC’ and methylation status was seen. An elevated minimum ADC was more likely in the methylated compared to the unmethylated MGMT group (U = 56, P = 0.0561). In contrast, utilising a two-mixture model histogram approach, a significant reduction in mean measure of the ‘low ADC’ component within the histogram was associated with an MGMT promoter methylation subtype (P < 0.0246). This study shows that within the same patient cohort, the method selected to analyse ADC measures has a significant bearing on the use of that metric as a surrogate marker of MGMT status. Thus for dMRI data to be clinically useful, consistent methods of data analysis need to be established prior to establishing any relationship with genetic or epigenetic profiling.

  5. Apparent Diffusion Coefficient (ADC value: a potential imaging biomarker that reflects the biological features of rectal cancer.

    Directory of Open Access Journals (Sweden)

    Yiqun Sun

    Full Text Available OBJECTIVE: We elected to analyze the correlation between the pre-treatment apparent diffusion coefficient (ADC and the clinical, histological, and immunohistochemical status of rectal cancers. MATERIALS AND METHODS: Forty-nine rectal cancer patients who received surgical resection without neoadjuvant therapy were selected that underwent primary MRI and diffusion-weighted imaging (DWI. Tumor ADC values were determined and analyzed to identify any correlations between these values and pre-treatment CEA or CA19-9 levels, and/or the histological and immunohistochemical properties of the tumor. RESULTS: Inter-observer agreement of confidence levels from two separate observers was suitable for ADC measurement (k  =  0.775. The pre-treatment ADC values of different T stage tumors were not equal (p  =  0.003. The overall trend was that higher T stage values correlated with lower ADC values. ADC values were also significantly lower for the following conditions: tumors with the presence of extranodal tumor deposits (p  =  0.006 and tumors with CA19-9 levels ≥ 35 g/ml (p  =  0.006. There was a negative correlation between Ki-67 LI and the ADC value (r  =  -0.318, p  =  0.026 and between the AgNOR count and the ADC value (r  =  -0.310, p  =  0.030. CONCLUSION: Significant correlations were found between the pre-treatment ADC values and T stage, extranodal tumor deposits, CA19-9 levels, Ki-67 LI, and AgNOR counts in our study. Lower ADC values were associated with more aggressive tumor behavior. Therefore, the ADC value may represent a useful biomarker for assessing the biological features and possible relationship to the status of identified rectal cancers.

  6. Using the apparent diffusion coefficient to identifying MGMT promoter methylation status early in glioblastoma: importance of analytical method

    International Nuclear Information System (INIS)

    Accurate knowledge of O6-methylguanine methyltransferase (MGMT) gene promoter subtype in patients with glioblastoma (GBM) is important for treatment. However, this test is not always available. Pre-operative diffusion MRI (dMRI) can be used to probe tumour biology using the apparent diffusion coefficient (ADC); however, its ability to act as a surrogate to predict MGMT status has shown mixed results. We investigated whether this was due to variations in the method used to analyse ADC. We undertook a retrospective study of 32 patients with GBM who had MGMT status measured. Matching pre-operative MRI data were used to calculate the ADC within contrast enhancing regions of tumour. The relationship between ADC and MGMT was examined using two published ADC methods. A strong trend between a measure of ‘minimum ADC’ and methylation status was seen. An elevated minimum ADC was more likely in the methylated compared to the unmethylated MGMT group (U = 56, P = 0.0561). In contrast, utilising a two-mixture model histogram approach, a significant reduction in mean measure of the ‘low ADC’ component within the histogram was associated with an MGMT promoter methylation subtype (P < 0.0246). This study shows that within the same patient cohort, the method selected to analyse ADC measures has a significant bearing on the use of that metric as a surrogate marker of MGMT status. Thus for dMRI data to be clinically useful, consistent methods of data analysis need to be established prior to establishing any relationship with genetic or epigenetic profiling

  7. Intra- and interobserver variability of whole-tumour apparent diffusion coefficient measurements in nephroblastoma: a pilot study

    Energy Technology Data Exchange (ETDEWEB)

    Littooij, Annemieke S. [University Medical Centre Utrecht, Department of Radiology, Utrecht (Netherlands); Humphries, Paul D. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); University College London Hospital, Department of Radiology, London (United Kingdom); Olsen, Oeystein E. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom)

    2015-10-15

    The apparent diffusion coefficient (ADC) is potentially useful for assessing treatment response in nephroblastoma (Wilms tumour). However the precision of ADC measurements in these heterogeneous lesions is unknown. To assess intra- and interobserver variability of whole-tumour ADC measurements in viable parts of nephroblastomas at diagnosis and after preoperative chemotherapy. We included children with histopathologically proven nephroblastoma who had undergone MRI with diffusion-weighted imaging before and after preoperative chemotherapy. Three independent observers performed whole-tumour ADC measurements of all lesions, excluding non-enhancing areas. One observer evaluated all lesions on two occasions. We performed analyses using Bland-Altman plots and concordance correlation coefficient (CCC) calculations with 95% limits of agreement for median ADC, difference between pre- and post-chemotherapy median ADC (ADC shift) and percentage of pixels with ADC values <1.0 x 10{sup -3} mm{sup 2}/s. In 22 lesions (13 pretreatment and 9 post-treatment) in 10 children the interobserver variability in median ADC and ADC shift were within the interval of approximately ±0.1 x 10{sup -3} mm{sup 2}/s (limits of agreement for median ADC ranged -0.08-0.11 x 10{sup -3} mm{sup 2}/s and for ADC-shift -0.11-0.09 x 10{sup -3} mm{sup 2}/s). The interobserver variability for percentage of low-ADC pixels was larger and also biased. The calculated CCC confirmed good intra- and interobserver agreement (ρ-c ranging from 0.968 to 0.996). Measurements of whole-tumour ADC values excluding necrotic areas seem to be sufficiently precise for detection of chemotherapy-related change. (orig.)

  8. Improvised Levelset method for segmentation and grading of brain tumors in dynamic contrast susceptibility and apparent diffusion coefficient magnetic resonance images

    Directory of Open Access Journals (Sweden)

    Vijayakumar Chinnadurai

    2010-05-01

    Full Text Available A novel Neuro – level set algorithm is proposed and evaluated for simultaneous segmentation and grading of brain tumors. The algorithm utilizes vascular and cellular information provided by the reconstructed images of dynamic contrast susceptibility magnetic resonance images and apparent diffusion coefficient images. The reconstructed images are relative cerebral blood volume (rCBV image, time to peak (TTP image and percentage of base at peak (PBP image along with apparent diffusion coefficient (ADC maps. The proposed neural - levelset algorithm utilizes a neural block to provide the speed image for the levelset methods. In this study, two different architectures of levelset method have been implemented and their results are compared. The results show that the proposed Neuro- Levelset method performs better in differentiating the tumor, edema,necrosis in reconstructed images of dynamic contrast susceptibility magnetic resonance images and apparent diffusion coefficient MR images.

  9. Change apparent diffusion coefficient immediately after recanalization through intra-arterial revascularization therapy in acute ischemic stroke

    Energy Technology Data Exchange (ETDEWEB)

    Roh, Ji Eun; Yeom, Joeng A; Kim, Young Soo; Yoon, Chang Hyo; Park, Min Gyu; Park, Kyung Pil; Baik, Seung Kug [Pusan National University Yangsan Hospital, Yangsan (Korea, Republic of)

    2016-04-15

    Intra-arterial revascularization therapy (IART) for acute ischemic stroke has become increasingly popular recently. However, early change in apparent diffusion coefficient (ADC) values after full recanalization in human stroke has not received much attention. The aim of this study was to evaluate ADC changes immediately after interventional full-recanalization in patients with acute ischemic stroke. ADC values of 25 lesions from 18 acute ischemic stroke patients were recorded with both pre- and post-recanalization ADC maps. Measurement was done by placing region of interests over the representative images of the lesion. For analysis, lesions were divided into territorial infarction (TI) and watershed infarction (WI). Mean ADC values of the overall 25 lesions before IART were 415.12 × 10-6 mm{sup 2}/sec, and increased to 619.08 × 10-6 mm{sup 2}/sec after the IART. Average relative ADC (rADC) value for 22 TI increased from 0.59 to 0.92 (p < 0.000), whereas, average rADC value for 3 WI did not change significantly. There was a conspicuous increase of ADC values immediately after full-recanalization in TI lesions. On the other hand, WI lesions did not show significant change in ADC values after recanalization.

  10. Enhancing tumor apparent diffusion coefficient histogram skewness stratifies the postoperative survival in recurrent glioblastoma multiforme patients undergoing salvage surgery.

    Science.gov (United States)

    Zolal, Amir; Juratli, Tareq A; Linn, Jennifer; Podlesek, Dino; Sitoci Ficici, Kerim Hakan; Kitzler, Hagen H; Schackert, Gabriele; Sobottka, Stephan B; Rieger, Bernhard; Krex, Dietmar

    2016-05-01

    Objective To determine the value of apparent diffusion coefficient (ADC) histogram parameters for the prediction of individual survival in patients undergoing surgery for recurrent glioblastoma (GBM) in a retrospective cohort study. Methods Thirty-one patients who underwent surgery for first recurrence of a known GBM between 2008 and 2012 were included. The following parameters were collected: age, sex, enhancing tumor size, mean ADC, median ADC, ADC skewness, ADC kurtosis and fifth percentile of the ADC histogram, initial progression free survival (PFS), extent of second resection and further adjuvant treatment. The association of these parameters with survival and PFS after second surgery was analyzed using log-rank test and Cox regression. Results Using log-rank test, ADC histogram skewness of the enhancing tumor was significantly associated with both survival (p = 0.001) and PFS after second surgery (p = 0.005). Further parameters associated with prolonged survival after second surgery were: gross total resection at second surgery (p = 0.026), tumor size (0.040) and third surgery (p = 0.003). In the multivariate Cox analysis, ADC histogram skewness was shown to be an independent prognostic factor for survival after second surgery. Conclusion ADC histogram skewness of the enhancing lesion, enhancing lesion size, third surgery, as well as gross total resection have been shown to be associated with survival following the second surgery. ADC histogram skewness was an independent prognostic factor for survival in the multivariate analysis. PMID:26830088

  11. In Vitro Assessment of Factors Affecting the Apparent Diffusion Coefficient of Ramos Cells Using Bio-phantoms

    Directory of Open Access Journals (Sweden)

    Sasaki,Takanori

    2012-06-01

    Full Text Available The roles of cell density, extracellular space, intracellular factors, and apoptosis induced by the molecularly targeted drug rituximab on the apparent diffusion coefficient (ADC values were investigated using bio-phantoms. In these bio-phantoms, Ramos cells (a human Burkittセs lymphoma cell line were encapsulated in gellan gum. The ADC values decreased linearly with the increase in cell density, and declined steeply when the extracellular space became less than 4 μm. The analysis of ADC values after destruction of the cellular membrane by sonication indicated that approximately 65% of the ADC values of normal cells originate from the cell structures made of membranes and that the remaining 35% originate from intracellular components. Microparticles, defined as particles smaller than the normal cells, increased in number after rituximab treatments, migrated to the extracellular space and significantly decreased the ADC values of bio-phantoms during apoptosis. An in vitro study using bio-phantoms was conducted to quantitatively clarify the roles of cellular factors and of extracellular space in determining the ADC values yielded by tumor cells and the mechanism by which apoptosis changes those values.

  12. 3He Neutron Spin Filter cell development program at JCNS

    International Nuclear Information System (INIS)

    In order to produce high-quality 3He Neutron Spin Filters (NSF) with a high polarisation level, it is necessary to achieve a long 3He relaxation time by the reduction of the wall relaxation. This requires one to minimise the amount of impurities at the surface of the glass cells, and to have as few contaminants as possible in the gas filling system. In this report we describe the detailed procedure we employ to produce 3He cells using our newly built filling station. The obtained life times for a number of cells are practically approaching the fundamental limit imposed by the dipole-dipole interaction between 3He atoms.

  13. Model formalism of liquid 3He-B at equilibrium

    International Nuclear Information System (INIS)

    The approximate formal treatment of the nuclear spin system of normal liquid 3He given some time ago is extended to the ordered 3He phase. The formalism leads to the prediction of normal thermal behavior of 3He-B at lower pressures and at temperatures approaching its phase-boundary temperatures. In contrast to the disordered normal liquid phase, which is thermally anomalous, the entropy of the 3He-B decreases on isothermal compression, or its isobaric volume expansion coefficient is positive. The equilibrium thermal behavior of ordered 3He-B is thus qualitatively different from that of disordered liquid 3He. Experimental control of these aspects of the liquid 3He phase transformation is lacking at the present time. Both early and new 3He-B paramagnetic susceptibility data, extended recently over a wide reduced-temperature range, disclose a fundamental competition between the spontaneous ordering mechanism responsible for the existence of 3He-B and the specific ordering process imposed upon this phase on application of an external constant and uniform magnetic field. As a consequence, magnetized 3He-B will be shown to increase its entropy on isothermal magnetization and to cool on adiabatic magnetization. The magnetocaloric effect is, however, only moderate. The competition of the ordering process leads to the delay or possibly even to the suppression of the formation of the ordered phase, a state of affairs foreseen in our earlier work. At low or moderate magnetic field strengths, the zero-field phase-boundary temperatures are shown to shift toward lower temperatures while, simultaneously, the order of the phase change decreases, from second order, in the absence of the field, to first order. Although of model-theoretic character, involving limitations of various types, the rich physical content of 3He-B at equilibrium clearly emerges in the present work

  14. Quantitative {sup 1}H and hyperpolarized {sup 3}He magnetic resonance imaging: Comparison in chronic obstructive pulmonary disease and healthy never-smokers

    Energy Technology Data Exchange (ETDEWEB)

    Owrangi, Amir M., E-mail: aowrangi@robats.ca [Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada N6A 5K8 (Canada); Graduate Program in Biomedical Engineering, The University of Western Ontario, London (Canada); Wang, Jian X., E-mail: jxwang@robats.ca [Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada N6A 5K8 (Canada); Applied Science Laboratories, General Electric Healthcare (Canada); Wheatley, Andrew, E-mail: awheat@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada N6A 5K8 (Canada); McCormack, David G., E-mail: David.Mccormack@lhsc.on.ca [Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada N6A 5K8 (Canada); Division of Respirology, Department of Medicine, The University of Western Ontario, London (Canada); Parraga, Grace, E-mail: gparraga@robats.ca [Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada N6A 5K8 (Canada); Graduate Program in Biomedical Engineering, The University of Western Ontario, London (Canada); Department of Medical Imaging, The University of Western Ontario, London (Canada); Department of Medical Biophysics, The University of Western Ontario, London (Canada)

    2014-01-15

    Objective: The aim of this study was to quantitatively evaluate the relationship between short echo time pulmonary {sup 1}H magnetic resonance imaging (MRI) signal intensity (SI) and {sup 3}He MRI apparent diffusion coefficients (ADC), high-resolution computed tomography (CT) measurements of emphysema, and pulmonary function measurements. Materials and methods: Nine healthy never-smokers and 11 COPD subjects underwent same-day plethysmography, spirometry, short echo time ((TE) = 1.2 ms) {sup 1}H and diffusion-weighted hyperpolarized {sup 3}He MRI (b = 1.6 s/cm{sup 2}) at 3.0 T. In addition, for COPD subjects only, CT densitometry was also performed. Results: Mean {sup 1}H SI was significantly greater for never-smokers (12.1 ± 1.1 arbitrary units (AU)) compared to COPD subjects (10.9 ± 1.3 AU, p = 0.04). The {sup 1}H SI AP-gradient was also significantly greater for never-smokers (0.40 AU/cm, R{sup 2} = 0.94) compared to COPD subjects (0.29 AU/cm, R{sup 2} = 0.968, p = 0.05). There was a significant correlation between {sup 1}H SI and {sup 3}He ADC (r = −0.58, p = 0.008) and significant correlations between {sup 1}H MR SI and CT measurements of emphysema (RA{sub 950}, r = −0.69, p = 0.02 and HU{sub 15}, r = 0.66, p = 0.03). Conclusions: The significant and moderately strong relationship between {sup 1}H SI and {sup 3}He ADC, as well as between {sup 1}H SI and CT measurements of emphysema suggests that these imaging methods and measurements may be quantifying similar tissue changes in COPD and that pulmonary {sup 1}H SI may be used to monitor emphysema as a complement to CT and noble gas MRI.

  15. Quantitative 1H and hyperpolarized 3He magnetic resonance imaging: Comparison in chronic obstructive pulmonary disease and healthy never-smokers

    International Nuclear Information System (INIS)

    Objective: The aim of this study was to quantitatively evaluate the relationship between short echo time pulmonary 1H magnetic resonance imaging (MRI) signal intensity (SI) and 3He MRI apparent diffusion coefficients (ADC), high-resolution computed tomography (CT) measurements of emphysema, and pulmonary function measurements. Materials and methods: Nine healthy never-smokers and 11 COPD subjects underwent same-day plethysmography, spirometry, short echo time ((TE) = 1.2 ms) 1H and diffusion-weighted hyperpolarized 3He MRI (b = 1.6 s/cm2) at 3.0 T. In addition, for COPD subjects only, CT densitometry was also performed. Results: Mean 1H SI was significantly greater for never-smokers (12.1 ± 1.1 arbitrary units (AU)) compared to COPD subjects (10.9 ± 1.3 AU, p = 0.04). The 1H SI AP-gradient was also significantly greater for never-smokers (0.40 AU/cm, R2 = 0.94) compared to COPD subjects (0.29 AU/cm, R2 = 0.968, p = 0.05). There was a significant correlation between 1H SI and 3He ADC (r = −0.58, p = 0.008) and significant correlations between 1H MR SI and CT measurements of emphysema (RA950, r = −0.69, p = 0.02 and HU15, r = 0.66, p = 0.03). Conclusions: The significant and moderately strong relationship between 1H SI and 3He ADC, as well as between 1H SI and CT measurements of emphysema suggests that these imaging methods and measurements may be quantifying similar tissue changes in COPD and that pulmonary 1H SI may be used to monitor emphysema as a complement to CT and noble gas MRI

  16. Prognostic value of diffusion-weighted imaging summation scores or apparent diffusion coefficient maps in newborns with hypoxic-ischemic encephalopathy

    Energy Technology Data Exchange (ETDEWEB)

    Cavalleri, Francesca; Todeschini, Alessandra [Azienda Unita Sanitaria Locale di Modena, Neuroradiology Unit, Department of Neuroscience, Nuovo Ospedale Civile S. Agostino Estense di Modena, Modena (Italy); Lugli, Licia; Pugliese, Marisa; Della Casa, Elisa; Gallo, Claudio; Frassoldati, Rossella; Ferrari, Fabrizio [Modena University Hospital, Institute of Pediatrics and Neonatal Medicine and NICU, Modena (Italy); D' Amico, Roberto [University of Modena and Reggio Emilia, Department of Clinical and Diagnostic Medicine and Public Health, Modena (Italy)

    2014-09-15

    The diagnostic and prognostic assessment of newborn infants with hypoxic-ischemic encephalopathy (HIE) comprises, among other tools, diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps. To compare the ability of DWI and ADC maps in newborns with HIE to predict the neurodevelopmental outcome at 2 years of age. Thirty-four term newborns with HIE admitted to the Neonatal Intensive Care Unit of Modena University Hospital from 2004 to 2008 were consecutively enrolled in the study. All newborns received EEG, conventional MRI and DWI within the first week of life. DWI was analyzed by means of summation (S) score and regional ADC measurements. Neurodevelopmental outcome was assessed with a standard 1-4 scale and the Griffiths Mental Developmental Scales - Revised (GMDS-R). When the outcome was evaluated with a standard 1-4 scale, the DWI S scores showed very high area under the curve (AUC) (0.89) whereas regional ADC measurements in specific subregions had relatively modest predictive value. The lentiform nucleus was the region with the highest AUC (0.78). When GMDS-R were considered, DWI S scores were good to excellent predictors for some GMDS-R subscales. The predictive value of ADC measurements was both region- and subscale-specific. In particular, ADC measurements in some regions (basal ganglia, white matter or rolandic cortex) were excellent predictors for specific GMDS-R with AUCs up to 0.93. DWI S scores showed the highest prognostic value for the neurological outcome at 2 years of age. Regional ADC measurements in specific subregions proved to be highly prognostic for specific neurodevelopmental outcomes. (orig.)

  17. Ions Preheated in 3He-Rich Solar Particle Events

    Institute of Scientific and Technical Information of China (English)

    王德焴

    2003-01-01

    A wave-particle resonance absorption model in the two-ion plasma is suggested in explanation to the coronal ions preheating in 3He-rich solar particle events. It is found that 3He and Fe ions are preferably preheated by the ion-ion hybrid waves at their fundamental and second harmonic ion cyclotron frequencies, respectively.

  18. magnetic resonance of 3He nuclei in porous media

    International Nuclear Information System (INIS)

    The data on 3He spin kinetics in porous media above the Fermi temperature of 3He are summarized. Presented results are obtained in Kazan Federal University in last ten years and are the base of developing method of helium porometry. Guidelines for investigation of samples with unknown pore sizes and superficial their properties are proposed

  19. Improving malignancy prediction in breast lesions with the combination of apparent diffusion coefficient and dynamic contrast-enhanced kinetic descriptors

    International Nuclear Information System (INIS)

    Aim: To assess how the joint use of apparent diffusion coefficient (ADC) and kinetic parameters (uptake phase and delayed enhancement characteristics) from dynamic contrast-enhanced (DCE) can boost the ability to predict breast lesion malignancy. Materials and methods: Breast magnetic resonance examinations including DCE and diffusion-weighted imaging (DWI) were performed on 51 women. The association between kinetic parameters and ADC were evaluated and compared between lesion types. Models with binary outcome of malignancy were studied using generalized estimating equations (GEE), (GEE), and using kinetic parameters and ADC values as malignancy predictors. Model accuracy was assessed using the corrected maximum quasi-likelihood under the independence confidence criterion (QICC). Predicted probability of malignancy was estimated for the best model. Results: ADC values were significantly associated with kinetic parameters: medium and rapid uptake phase (p<0.001) and plateau and washout curve types (p=0.004). Comparison between lesion type showed significant differences for ADC (p=0.001), early phase (p<0.001), and curve type (p<0.001). The predicted probabilities of malignancy for the first ADC quartile (≤1.17×10−3 mm2/s) and persistent, plateau and washout curves, were 54.6%, 86.9%, and 97.8%, respectively, and for the third ADC quartile (≥1.51×10−3 mm2/s) were 3.2%, 15.5%, and 54.8%, respectively. The predicted probability of malignancy was less than 5% for 18.8% of the lesions and greater than 33% for 50.7% of the lesions (24/35 lesions, corresponding to a malignancy rate of 68.6%). Conclusion: The best malignancy predictors were low ADCs and washout curves. ADC and kinetic parameters provide differentiated information on the microenvironment of the lesion, with joint models displaying improved predictive performance. -- Highlights: •ADC and kinetic parameters provide diverse information regarding lesion environment. •The best predictors of

  20. Nuclear Overhauser Enhancement imaging of glioblastoma at 7 Tesla: region specific correlation with apparent diffusion coefficient and histology.

    Directory of Open Access Journals (Sweden)

    Daniel Paech

    Full Text Available To explore the correlation between Nuclear Overhauser Enhancement (NOE-mediated signals and tumor cellularity in glioblastoma utilizing the apparent diffusion coefficient (ADC and cell density from histologic specimens. NOE is one type of chemical exchange saturation transfer (CEST that originates from mobile macromolecules such as proteins and might be associated with tumor cellularity via altered protein synthesis in proliferating cells.For 15 patients with newly diagnosed glioblastoma, NOE-mediated CEST-contrast was acquired at 7 Tesla (asymmetric magnetization transfer ratio (MTRasym at 3.3ppm, B1 = 0.7 μT. Contrast enhanced T1 (CE-T1, T2 and diffusion-weighted MRI (DWI were acquired at 3 Tesla and coregistered. The T2 edema and the CE-T1 tumor were segmented. ADC and MTRasym values within both regions of interest were correlated voxelwise yielding the correlation coefficient rSpearman (rSp. In three patients who underwent stereotactic biopsy, cell density of 12 specimens per patient was correlated with corresponding MTRasym and ADC values of the biopsy site.Eight of 15 patients showed a weak or moderate positive correlation of MTRasym and ADC within the T2 edema (0.16≤rSp≤0.53, p0.05, n = 4 or yielded rSp≈0 (p0.05, n = 6. The biopsy-analysis within CE-T1 tumor revealed a strong positive correlation between tumor cellularity and MTRasym values in two of the three patients (rSppatient3 = 0.69 and rSppatient15 = 0.87, p<0.05, while the correlation of ADC and cellularity was heterogeneous (rSppatient3 = 0.545 (p = 0.067, rSppatient4 = -0.021 (p = 0.948, rSppatient15 = -0.755 (p = 0.005.NOE-imaging is a new contrast promising insight into pathophysiologic processes in glioblastoma regarding cell density and protein content, setting itself apart from DWI. Future studies might be based on the assumption that NOE-mediated CEST visualizes cellularity more accurately than ADC, especially in the CE-T1 tumor region.

  1. Peritumoral apparent diffusion coefficients for prediction of lymphovascular invasion in clinically node-negative invasive breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Naoko; Mugikura, Shunji; Takasawa, Chiaki; Shimauchi, Akiko; Ota, Hideki; Takase, Kei; Takahashi, Shoki [Tohoku University Graduate School of Medicine, Department of Diagnostic Radiology, Sendai (Japan); Miyashita, Minoru; Ishida, Takanori [Tohoku University Graduate School of Medicine, Department of Surgical Oncology, Sendai (Japan); Kasajima, Atsuko [Tohoku University Graduate School of Medicine, Department of Pathology, Sendai (Japan); Kodama, Tetsuya [Tohoku University Graduate School of Medicine, Department of Biomedical Engineering, Sendai (Japan)

    2016-02-15

    To evaluate whether visual assessment of T2-weighted imaging (T2WI) or an apparent diffusion coefficient (ADC) could predict lymphovascular invasion (LVI) status in cases with clinically node-negative invasive breast cancer. One hundred and thirty-six patients with 136 lesions underwent MRI. Visual assessment of T2WI, tumour-ADC, peritumoral maximum-ADC and the peritumour-tumour ADC ratio (the ratio between them) were compared with LVI status of surgical specimens. No significant relationship was found between LVI and T2WI. Tumour-ADC was significantly lower in the LVI-positive (n = 77, 896 ± 148 x 10{sup -6} mm{sup 2}/s) than the LVI-negative group (n = 59, 1002 ± 163 x 10{sup -6} mm{sup 2}/s; p < 0.0001). Peritumoral maximum-ADC was significantly higher in the LVI-positive (1805 ± 355 x 10{sup -6} mm{sup 2}/s) than the LVI-negative group (1625 ± 346 x 10{sup -6} mm{sup 2}/s; p = 0.0003). Peritumour-tumour ADC ratio was significantly higher in the LVI-positive (2.05 ± 0.46) than the LVI-negative group (1.65 ± 0.40; p < 0.0001). Receiver operating characteristic curve analysis revealed that the area under the curve (AUC) of the peritumour-tumour ADC ratio was the highest (0.81). The most effective threshold for the peritumour-tumour ADC ratio was 1.84, and the sensitivity, specificity, positive predictive value and negative predictive value were 77 % (59/77), 76 % (45/59), 81 % (59/73) and 71 % (45/63), respectively. We suggest that the peritumour-tumour ADC ratio can assist in predicting LVI status on preoperative imaging. (orig.)

  2. Diagnostic accuracy of apparent diffusion coefficient and 123I-metaiodobenzylguanidine for differentiation of multiple system atrophy and Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Atsushi Umemura

    Full Text Available BACKGROUND: It is often hard to differentiate Parkinson's disease (PD and parkinsonian variant of multiple system atrophy (MSA-P, especially in the early stages. Cardiac sympathetic denervation and putaminal rarefaction are specific findings for PD and MSA-P, respectively. PURPOSE: We investigated diagnostic accuracy of putaminal apparent diffusion coefficient (ADC test for MSA-P and (123I-metaiodobenzylguanidine (MIBG scintigram for PD, especially in early-stage patients. METHODS: The referral standard diagnosis of PD and MSA-P were the diagnostic criteria of the United Kingdom Parkinson's Disease Society Brain Bank Criteria and the second consensus criteria, respectively. Based on the referral standard criteria, diagnostic accuracy [area under the receiver-operator characteristic curve (AUC, sensitivity and specificity] of the ADC and MIBG tests was estimated retrospectively. Diagnostic accuracy of these tests performed within 3 years of symptom onset was also investigated. RESULTS: ADC and MIBG tests were performed on 138 patients (20 MSA and 118 PD. AUC was 0.95 and 0.83 for the ADC and MIBG tests, respectively. Sensitivity and specificity were 85.0% and 89.0% for MSA-P diagnosis by ADC test and 67.0% and 80.0% for PD diagnosis by MIBG test. When these tests were restricted to patients with disease duration ≤ 3 years, the sensitivity and specificity were 75.0% and 91.4% for the ADC test (MSA-P diagnosis and 47.7% and 92.3% for the MIBG test (PD diagnosis. CONCLUSIONS: Both tests were useful in differentiating between PD and MSA-P, even in the early stages. In early-stage patients, elevated putaminal ADC was a diagnostic marker for MSA-P. Despite high specificity of the MIBG test, careful neurological history and examinations were required for PD diagnosis because of possible false-negative results.

  3. Feasibility study of a sup 3 He-magnetometer for neutron electric dipole moment experiments

    CERN Document Server

    Borisov, Y; Leduc, M; Lobashev, V; Otten, E W; Sobolev, Y

    2000-01-01

    We report on a sup 3 He-magnetometer capable of detecting tiny magnetic field fluctuations of less than 10 sup - sup 1 sup 4 T in experiments for measuring the electric dipole moment (EDM) of the neutron. It is based on the Ramsey technique of separated oscillating fields and uses nuclear spin-polarized sup 3 He gas which is stored in two vessels of V approx =10 l in a sandwich-type arrangement around the storage bottle for ultra-cold neutrons (UCN). The gas is polarized by means of optical pumping in a separate, small discharge cell at pressures around 0.5 mbar and is then expanded into the actual magnetometer volume. To detect the polarization of sup 3 He gas at the end of the storage cycle the gas is pumped out by means of an oil-diffusion pump and compressed again into the discharge cell where optical detection of nuclear polarization is used.

  4. Tumor Extension in High-Grade Gliomas Assessed with Diffusion Magnetic Resonance Imaging: Values and Lesion-to-Brain Ratios of Apparent Diffusion Coefficient and Fractional Anisotropy

    Energy Technology Data Exchange (ETDEWEB)

    Westen, D. van; Laett, J.; Englund, E.; Brockstedt, S.; Larsson, E.M. [Lund Univ. Hospital (Sweden). Depts. of Radiology, of Medical Radiation Physics and of Pathology and Cytology

    2006-04-15

    Purpose: To determine whether the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) can distinguish tumor-infiltrated edema in gliomas from pure edema in meningiomas and metastases. Material and Methods: Thirty patients were studied: 18 WHO grade III or IV gliomas, 7 meningiomas, and 5 metastatic lesions. ADC and FA were determined from ROIs placed in peritumoral areas with T2-signal changes, adjacent normal appearing white matter (NAWM), and corresponding areas in the contralateral healthy brain. Values and lesion-to-brain ratios from gliomas were compared to those from meningiomas and metastases. Results: Values and lesion-to-brain ratios of ADC and FA in peritumoral areas with T2-signal changes did not differ between gliomas, meningiomas, and metastases (P = 0.40, P = 0.40, P = 0.61, P 0.34). Values of ADC and FA and the lesion-to-brain ratio of FA in the adjacent NAWM did not differ between tumor types (P = 0.74, P = 0.25, and P = 0.31). The lesion-to-brain ratio of ADC in the adjacent NAWM was higher in gliomas than in meningiomas and metastases (P = 0.004), but overlapped between tumor types. Conclusion: Values and lesion-to-brain ratios of ADC and FA in areas with T2-signal changes surrounding intracranial tumors and adjacent NAWM were not helpful for distinguishing pure edema from tumor-infiltrated edema when data from gliomas, meningiomas, and metastases were compared.

  5. Usefulness of Diffusion-Weighted MR Imaging for Breast Lesions: Comparing the Apparent Diffusion Coefficient (ADC) Values and the Pathologic Results

    International Nuclear Information System (INIS)

    We wanted to evaluate the ability of the apparent diffusion coefficient (ADC) values to differentiate between benign and malignant breast lesions and the normal breast parenchyma. We used breast MRI, including DWI, to obtain images of 167 breast lesions (18 benign lesions and 149 malignant lesions) of 152 women (mean age: 48.6 years, range: 24-80 years). The mean ADC values of the malignant lesions were compared to those of the benign lesions and the normal parenchyma. We compared the ADC values of IDC, DCIS and other types of breast cancer and we also compared the ADC values with the nuclear grade of IDC. The mean ADC values of the malignant lesions were lower than those of the benign lesions and the normal parenchyma (p-3 mm2/s for discriminating between malignant and benign lesion showed a specificity of 53% and a sensitivity of 100%, and the ADC threshold value of 1.33 X 10-3 mm2/s showed a specificity of 93% and a sensitivity of 94% for discriminating between malignant and benign lesion.

  6. The Influence of the b-Value Combination on Apparent Diffusion Coefficient Based Differentiation Between Malignant and Benign Tissue in Cervical Cancer

    NARCIS (Netherlands)

    J.P. Hoogendam; W.M. Klerkx; G.A.P. de Kort; S. Bipat; R.P. Zweemer; D.M.D.S. Sie-Go; R.H.M. Verheijen; W.P.T.M. Mali; W.B. Veldhuis

    2010-01-01

    Purpose: To analyze the influence of different b-value combinations on apparent diffusion coefficient (ADC)based differentiation of known malignant and benign tissue in cervical cancer patients. Materials and Methods: A total of 35 patients with stage IB1, IB2, IIA cervical cancer underwent a 3.0T M

  7. Zeeman Relaxation of Cold Atomic Iron and Nickel in Collisions with 3He

    CERN Document Server

    Johnson, Cort; Brahms, Nathan; Doyle, John M; Kleppner, Daniel; Greytak, Thomas J

    2010-01-01

    We have measured the ratio of the diffusion cross-section to the angular momentum reorientation cross-section in the colliding Fe-3He and Ni-3He systems. Nickel (Ni) and iron (Fe) atoms are introduced via laser ablation into a cryogenically cooled experimental cell containing cold (< 1 K) 3He buffer gas. Elastic collisions rapidly cool the translational temperature of the ablated atoms to the helium temperature. The cross-section ratio is extracted by measuring the decays of the atomic Zeeman sublevels. For our experimental conditions, thermal energy is comparable to the Zeeman splitting. As a result, thermal excitations between Zeeman sublevels significantly impact the observed decay. To determine the cross-section ratio accurately, we introduce a model of Zeeman state dynamics that includes thermal excitations. We find the cross-section ratio for Ni-3He = 5 x 10^3 and Fe-3He <= 3 x 10^3 at 0.75 K in a 0.8 T magnetic field. These measurements are interpreted in the context of submerged shell suppressio...

  8. Degassing of 3H/3He, CFCs and SF6 by denitrification: measurements and two-phase transport simulations.

    Science.gov (United States)

    Visser, Ate; Schaap, Joris D; Broers, Hans Peter; Bierkens, Marc F P

    2009-01-26

    The production of N2 gas by denitrification may lead to the appearance of a gas phase below the water table prohibiting the conservative transport of tracer gases required for groundwater dating. We used a two-phase flow and transport model (STOMP) to study the reliability of 3H/3He, CFCs and SF6 as groundwater age tracers under agricultural land where denitrification causes degassing. We were able to reproduce the amount of degassing (R2=69%), as well as the 3H (R2=79%) and 3He (R2=76%) concentrations observed in a 3H/3He data set using simple 2D models. We found that the TDG correction of the 3H/3He age overestimated the control 3He/3He age by 2.1 years, due to the accumulation of 3He in the gas phase. The total uncertainty of degassed 3H/3He ages of 6 years (+/-2 sigma) is due to the correction of degassed 3He using the TDG method, but also due to the travel time in the unsaturated zone and the diffusion of bomb peak 3He. CFCs appear to be subject to significant degradation in anoxic groundwater and SF6 is highly susceptible to degassing. We conclude that 3H/3He is the most reliable method to date degassed groundwater and that two-phase flow models such as STOMP are useful tools to assist in the interpretation of degassed groundwater age tracer data. PMID:19042054

  9. Feasibility studies of D—3He fusion power in China

    Institute of Scientific and Technical Information of China (English)

    DengBai-Quan; FengKei-Ming; 等

    1997-01-01

    The systematic study on D-3He advanced fuel fusion in China has been performed.Comparisons between D-3He and D-T fuel cycles in physics,engineering,environmental safety and so on have been made.D-3He fusion offers significant adavantages for reducing the neutron yield by a factor of 10-60,The 3He resource and mining possibility are investigated.The energy payback factor of 97 for mining lunar 3He resource is calculated.The operating parameter scope for D-3He fueled Tokamak reactor is analyzed.The prompt energy broadening for fusion products is calculated and results are consistent with those obtained by Lehner using a different method.Centrally peaked current drive with high efficiency is studied utilizing plasma synchrotron radiation.Centrally peaked current drive with gigh efficiency is studied utilizing plasma synchrotron radiation.More than 80% of plasma current required can be driven passively.A D-3He fueled Tokamak commercial reactor-Mooncity was designed.Neutronics calculations show that the radioactivity,afterheat,BHP value for Mooncity are 10-60 times less than those for D-T fusion.

  10. D-3He fuel cycles for neutron lean reactors

    International Nuclear Information System (INIS)

    The intrinsic potential of D-3He as a reactor fuel is investigated for a large range of 3He to D density ratios. A steady-state zero-dimensional reactor model is developed in which much care is attributed to a proper treatment of fast fusion products. Useful ranges of reactor parameters as well as temperature-density windows for driven and ignited operation are identified. Various figures of merit are calculated, such as power densities, net power production, neutron production, tritium load and radiative power. These results suggest several optimistic conclusions about the performance of D-3He as a reactor fuel

  11. The diagnostic value of diffusion-weighted imaging and the apparent diffusion coefficient values in the differentiation of benign and malignant breast lesions

    International Nuclear Information System (INIS)

    The goal of our study was to evaluate the diagnostic efficacy of diffusion-weighted imaging (DWI) in the differentiation of benign and malignant breast lesions. Between June 2012 and March 2013, 60 patients with 63 lesions (age range 29-70 years, mean age 48.6 years) were included in our study. All lesions, except complicated cysts and intra-mammary lymph nodes, were confirmed histopathologically. The patients were evaluated with a 1.5 Tesla MR scanner using dedicated bilateral breast coil. DWI images were obtained by echo planar imaging sequence and 'b' values were selected as 200, 600 and 1000 s/mm2. Apparent diffusion coefficient (ADC) values of both breast lesions and the normal fibroglandular tissue of the contralateral breast were calculated and statistically compared using Shapiro-Wilk test, Student's t-test, Mann-Whitney U test, chi-square test and the receiver operating curve. Of 63 lesions, 22 were malignant and 41 were benign. In malignant lesions, the mean ADC values were 1.40 ± 0.41 × 10−3mm2/s for b = 200, 1.05 ± 0.28 × 10−3mm2/s for b = 600 and 0.91 ± 0.20 × 10−3mm2/s for b = 1000 and in benign lesions, the mean ADC values were 2.13 ± 0.85 × 10−3mm2/s for b = 200, 1.64 ± 0.47 × 10−3mm2/s for b = 600 and 1.40 ± 0.43 × 10−3mm2/s for b = 1000. The success of ADC values in differentiation of benign and malignant lesions was statistically significant (P = 0.0001). The threshold values were determined to be 1.50 × 10−3mm2/s for b = 200, 1.22 × 10−3mm2/s for b = 600 and 0.98 × 10−3mm2/s for b = 1000 (P < 0.05). DWI can be an effective radiological method in the differentiation of benign and malignant breast lesions.

  12. Usefulness of Diffusion-Weighted MR Imaging for Breast Lesions: Comparing the Apparent Diffusion Coefficient (ADC) Values and the Pathologic Results

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Hye Shin; Chang, Yun Woo; Choi, Kyung Hee; Kim, Hyun Joo; Hong, Seong Suk; Hwang, Jung Hwa; Kwon, Kui Hyang [Dept.of Radiology, Soonchunhyang University Hospital, Seoul (Korea, Republic of); Kim, Yong Bae [Dept. of Preventive Medicine, Soonchunhyang University Hospital, Seoul (Korea, Republic of)

    2011-04-15

    We wanted to evaluate the ability of the apparent diffusion coefficient (ADC) values to differentiate between benign and malignant breast lesions and the normal breast parenchyma. We used breast MRI, including DWI, to obtain images of 167 breast lesions (18 benign lesions and 149 malignant lesions) of 152 women (mean age: 48.6 years, range: 24-80 years). The mean ADC values of the malignant lesions were compared to those of the benign lesions and the normal parenchyma. We compared the ADC values of IDC, DCIS and other types of breast cancer and we also compared the ADC values with the nuclear grade of IDC. The mean ADC values of the malignant lesions were lower than those of the benign lesions and the normal parenchyma (p<0.001, respectively). The mean ADC value of IDC was lower than those of DCIS and other breast cancers (p<0.001, respectively). The mean ADC value of mucinous carcinoma among the other breast cancer was characteristic high compared with that of the normal parenchyma. There was no significant differentiation of the ADC values between the nuclear grades of IDC (p<0.828). The ADC threshold value of 0.98 X 10{sup -3} mm{sup 2}/s for discriminating between malignant and benign lesion showed a specificity of 53% and a sensitivity of 100%, and the ADC threshold value of 1.33 X 10{sup -3} mm{sup 2}/s showed a specificity of 93% and a sensitivity of 94% for discriminating between malignant and benign lesion.

  13. Safeguards Technology Factsheet 3He-free Neutron Coincidence Counter

    International Nuclear Information System (INIS)

    A full scale thermal neutron coincidence counter (High Level Neutron Counter - Boron: HLNB) based on 3He alternative detection technology was designed and built at LANL and field tested at Plutonium Conversion Development Facility (PCDF) of Japan Atomic Energy Agency (JAEA) during FY15. HLNB is based on boron-lined proportional plates that replace the traditional 3He proportional tubes and was designed as a direct alternative to 3He-based High Level Neutron Coincidence Counter (HLNC-II). During the JAEA field trial the HLNB demonstrated comparable performance to HLNC-II, which represents a key development in the area of 3He alternative technologies and provides a complete demonstration of the technology for nuclear safeguards applications including high mass MOX samples.

  14. Ultrasound Attenuation in Liquid ^3He/High Porosity Aerogel

    Science.gov (United States)

    Choi, H. C.; Mulders, N.

    2005-11-01

    High porosity silica aerogels have been extensively used to study the influence of disorder in p-wave superfluid ^3He. Experimental investigations performed during the last decade revealed three distinct superfluid phases in liquid ^3He /98% aerogel system. The three phases found in this system are called as A, B, and A1-like phases (using the same nomenclature as in the bulk), although only the spin component of the order parameter has been studied and found to resemble that of corresponding bulk phases. A complete understanding of the microscopic structure of the p-wave superfluid phases requires identification of both orbital and spin components of the order parameter. Until now, there is no experimental attempt to directly probe the orbital structure in ^3He/aerogel system. To resolve this issue, we performed acoustic measurements by direct transmission of ultrasound through the ^3He/98% aerogel sample. We will present and discuss our preliminary results.

  15. Polar Phase of Superfluid (3)He in Anisotropic Aerogel.

    Science.gov (United States)

    Dmitriev, V V; Senin, A A; Soldatov, A A; Yudin, A N

    2015-10-16

    We report the first observation of the polar phase of superfluid (3)He. This phase appears in (3)He confined in a new type of aerogel with a nearly parallel arrangement of strands which play the role of ordered impurities. Our experiments qualitatively agree with theoretical predictions and suggest that in other systems with unconventional Cooper pairing (e.g., in unconventional superconductors) similar phenomena may be found in the presence of anisotropic impurities.

  16. Analytic vortices in rotating superfluid 3He-A

    International Nuclear Information System (INIS)

    Recent works on analytic vortices in rotating 3He-A are reviewed. It is shown that the circular-hyperbolic vortex lattice has the lowest free energy in an axial magnetic field. The associated nuclear magnetic resonance satellites account for not only the observed satellite frequencies in a rotating 3He-A experiment but also the observed intensity of the satellite resonances. 15 references, 3 figures

  17. The 3He spectral function in light-front dynamics

    CERN Document Server

    Rinaldi, Matteo; Kaptari, Leonid; Pace, Emanuele; Salmè, Giovanni; Scopetta, Sergio

    2016-01-01

    A distorted spin-dependent spectral function for 3He is considered for the extraction of the transverse-momentum dependent parton distributions in the neutron from semi-inclusive deep inelastic electron scattering off polarized 3He at finite momentum transfers, where final state interactions are taken into account. The generalization of the analysis to a Poincar\\'e covariant framework within the light-front dynamics is outlined.

  18. K^- ^3He and K^+K^- interactions in the reaction pd -> ^3He K^+K^-

    CERN Document Server

    Grishina, V Yu; Kondratyuk, L A

    2006-01-01

    We investigate the K^- ^3He and K^+K^- interactions in the reaction pd -> ^3He K^+K^- near threshold and compare our model calculations with data from the MOMO experiment at COSY-Juelich. The data do not support a strong attraction between the K^- and ^3He system needed for formation of deeply bound K^- nuclear states. We also estimate upper limits for the a_0(980) and f_0(980) contributions to the produced K^+ K^- pairs.

  19. 3-He in the Milky Way Interstellar Medium: Ionization Structure

    CERN Document Server

    Bania, T M; Rood, Robert T; Wilson, T L; LaRocque, Jennifer M

    2007-01-01

    The cosmic abundance of the 3-He isotope has important implications for many fields of astrophysics. We are using the 8.665 GHz hyperfine transition of 3-He+ to determine the 3-He/H abundance in Milky Way HII regions and planetary nebulae. This is one in a series of papers in which we discuss issues involved in deriving accurate 3-He/H abundance ratios from the available measurements. Here we describe the ionization correction we use to convert the 3-He+/H+ abundance, y3+, to the 3-He/H abundance, y3. In principle the nebular ionization structure can significantly influence the y3 derived for individual sources. We find that in general there is insufficient information available to make a detailed ionization correction. Here we make a simple correction and assess its validity. The correction is based on radio recombination line measurements of H+ and 4-He+, together with simple core-halo source models. We use these models to establish criteria that allow us to identify sources that can be accurately corrected...

  20. Thermal hysteresis of the thermal conductivity in isotopically impure bcc 3He

    Science.gov (United States)

    Greenberg, A. S.; Armstrong, G.

    1980-11-01

    We have measured the thermal conductivity of bcc 3He containing 10 and 500 ppm 4He for temperatures below the isotopic phase separation. We find the conductivity measured during cooling can be significantly greater, as much as an order of magnitude, than upon warming. This hysteresis depends strongly on the molar volume and 4He concentration. We interpret our results in terms of phonon scattering from the boundary of solid 4He clusters formed by quantum diffusion and nucleated by crystalline faults.

  1. The (t,3He) and (3He,t) reactions as probes of Gamow-Teller strength

    CERN Document Server

    Zegers, R G T; Austin, S M; Bazin, D; Berg, G P A; Brown, B A; Cole, A L; Daito, I; Fujita, Y; Fujiwara, M; Galès, Sydney; Harakeh, M N; Hashimoto, H; Hayami, R; Hitt, G W; Howard, M E; Itoh, M; Jänecke, J; Kawabata, T; Kawase, K; Kinoshita, M; Nakamura, T; Nakanishi, K; Nakayama, S; Okamura, S; Richter, W A; Roberts, D A; Sherrill, B M; Shimbara, Y; Steiner, M; Uchida, M; Ueno, H; Van den Berg, A M; Yamagata, T; Yosoi, M; Austin, Sam M.

    2006-01-01

    Charge-exchange reactions are an important tool for determining weak-interaction rates. They provide stringent tests for nuclear structure models necessary for modeling astrophysical environments such as neutron stars and core-collapse supernovae. In this paper we demonstrate via a study of 26Mg(t,3He) that the (t,3He) reaction at 115 MeV/nucleon is an accurate probe for extracting Gamow-Teller strengths. This study is complemented by 26Mg(3He,t) data taken at 140 MeV/nucleon which allows for a comparison of T=2 analog states excited via the mirror reactions. A good correspondence is found between Gamow-Teller distributions measured via the 26Mg(3He,t) and 26Mg(p,n) experiments, indicating probe-independence of the strength extraction. Results from 26Mg(t,3He) and 26Mg(d,2He) also display good correspondence, showing that with the (t,3He) reaction a new tool has become available for studying Gamow-Teller strengths in the beta+ direction. Furthermore, we test shell-model calculations using the new USD-05B inte...

  2. Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: A multi-center study

    OpenAIRE

    Pope, WB; Qiao, XJ; Kim, HJ; Lai, A.; Nghiemphu, P; Xue, X.; Ellingson, BM; Schiff, D.; Aregawi, D; Cha, S; Puduvalli, VK; Wu, J.; Yung, WKA; Young, GS; Vredenburgh, J

    2012-01-01

    We have tested the predictive value of apparent diffusion coefficient (ADC) histogram analysis in stratifying progression-free survival (PFS) and overall survival (OS) in bevacizumab-treated patients with recurrent glioblastoma multiforme (GBM) from the multi-center BRAIN study. Available MRI's from patients enrolled in the BRAIN study (n = 97) were examined by generating ADC histograms from areas of enhancing tumor on T1 weighted post-contrast images fitted to a two normal distribution mixtu...

  3. Radiation measurement and inverse analysis techniques applied on the determination of the apparent mass diffusion coefficient for diverse contaminants and soil samples

    International Nuclear Information System (INIS)

    Full text of publication follows: The study of the dispersion of radioactive materials in soils and in engineering barriers plays an important role in the safety analysis of nuclear waste repositories. In order to proceed with such kind of study the involved physical properties must be determined with precision, including the apparent mass diffusion coefficient, which is defined as the ratio between the effective mass diffusion coefficient and the retardation factor. Many different experimental and estimation techniques are available on the literature for the identification of the diffusion coefficient and this work describes the implementation of that developed by Pereira et al [1]. This technique is based on non-intrusive radiation measurements and the experimental setup consists of a cylindrical column filled with compacted media saturated with water. A radioactive contaminant is mixed with a portion of the media and then placed in the bottom of the column. Therefore, the contaminant will diffuse through the uncontaminated media due to the concentration gradient. A radiation detector is used to measure the number of counts, which is associated to the contaminant concentration, at several positions along the column during the experiment. Such measurements are then used to estimate the apparent diffusion coefficient of the contaminant in the porous media by inverse analysis. The inverse problem of parameter estimation is solved with the Levenberg-Marquart Method of minimization of the least-square norm. The experiment was optimized with respect to the number of measurement locations, frequency of measurements and duration of the experiment through the analysis of the sensitivity coefficients and by using a D-optimum approach. This setup is suitable for studying a great number of combinations of diverse contaminants and porous media varying in composition and compacting, with considerable easiness and reliable results, and it was chosen because that is the

  4. (3)He MRI in healthy volunteers: preliminary correlation with smoking history and lung volumes.

    Science.gov (United States)

    Guenther, D; Eberle, B; Hast, J; Lill, J; Markstaller, K; Puderbach, M; Schreiber, W G; Hanisch, G; Heussel, C P; Surkau, R; Grossmann, T; Weiler, N; Thelen, M; Kauczor, H U

    2000-06-01

    MRI with hyperpolarized helium-3 ((3)He) provides high-resolution imaging of ventilated airspaces. The first aim of this (3)He-study was to compare observations of localized signal defects in healthy smokers and non-smokers. A second aim was to describe relationships between parameters of lung function, volume of inspired (3)He and signal-to-noise ratio. With Ethics Committee approval and informed consent, 12 healthy volunteers (seven smokers and five non-smokers) were studied. Imaging was performed in a 1.5 T scanner using a two-dimensional FLASH sequence at 30V transmitter amplitude (TR/TE/alpha = 11 ms/4.2 ms/microprocessor-controlled delivery device and imaged during single breath-holds. Images were evaluated visually, and scored using a prospectively defined 'defect-index'. Signal-to-noise ratio of the images were correlated with localization, (3)He volumes and static lung volumes. Due to poor image quality studies of two smokers were not eligible for the evaluation. Smokers differed from non-smokers in total number and size of defects: the 'defect-index' of smokers ranged between 0.8 and 6.0 (median = 1.1), that of non-smokers between 0.1 and 0.8 (median = 0.4). Intraindividually, an anteroposterior gradient of signal-to-noise ratio was apparent. Signal-to-noise ratio correlated with the estimated amount of hyperpolarization administered (r = 0. 77), but not with static lung volumes. We conclude that (3)He MRI is a sensitive measure to detect regional abnormalities in the distribution of ventilation in clinically healthy persons with normal pulmonary function tests.

  5. Evolution of D and $^{3}He$ in the Galaxy

    CERN Document Server

    Tosi, M P

    2000-01-01

    The predictions of Galactic chemical evolution models for D and $^3$He are described in connection with those on the other Galactic quantities for which observational constraints are available. Models in agreement with the largest set of data predict deuterium depletions from the Big Bang to the present epoch smaller than a factor of 3 and do not allow for D/H primordial abundances larger than $\\sim4\\times10^{-5}$. Models predicting higher D consumption do not reproduce other observed features of our Galaxy. If both the primordial D and $^3$He are low, models assuming that 90% of low-mass stars experience an extra-mixing during the red giant phase reproduce all the $^3$He observed abundances. The same percentage allows to fit also the observed carbon isotopic ratios, thus supporting the self-consistency of the extra-mixing mechanism.

  6. An Optical Cryostat with $^{3}$He Sorption Refrigerator

    CERN Document Server

    Trofimov, V N; Perminov, V G; Vdovin, V F; Vystavkin, A N

    2005-01-01

    An optical cryostat with $^{3}$He sorption refrigerator is described. The refrigerator is mounted on a copper plate with temperature 4.2 K in vacuum volume of a helium cryostat. It has two sorption steps: the first with working gas $^4$He is intended for condensation of $^{3}$He, the second with $^{3}$He for cooling down to 0.3 K. The cryostat is an independent device that does not contain the external gas communications aimed at reaching low temperatures, and working gases are stored in cans integrated with the cryostat. The refrigerator can be used together with the cryocoolers of Gifford--McMahon or pulse tube types with cooling power not less than 0.3 W/4 K, thus allowing operating without any liquid cryoagents.

  7. Light-Front Dynamics and the 3He Spectral Function

    CERN Document Server

    Pace, Emanuele; Kaptari, Leonid; Rinaldi, Matteo; Salme', Giovanni; Scopetta, Sergio

    2016-01-01

    Two topics are presented. The first one is a novel approach for a Poincare' covariant description of nuclear dynamics based on light-front Hamiltonian dynamics. The key quantity is the light-front spectral function, where both normalization and momentum sum rule can be satisfied at the same time. Preliminary results are discussed for an initial analysis of the role of relativity in the EMC effect in 3He. A second issue, very challenging, is considered in a non-relativistic framework, namely a distorted spin-dependent spectral function for 3He in order to take care of the final state interaction between the observed pion and the remnant in semi-inclusive deep inelastic electron scattering off polarized 3He. The generalization of the analysis within the light-front dynamics is outlined.

  8. Strong-Coupling and the Stripe Phase of ^3He

    Science.gov (United States)

    Wiman, Joshua J.; Sauls, J. A.

    2016-09-01

    Thin films of superfluid 3He were predicted, based on weak-coupling BCS theory, to have a stable phase which spontaneously breaks translational symmetry in the plane of the film. This crystalline superfluid, or "stripe" phase, develops as a one-dimensional periodic array of domain walls separating degenerate B phase domains. We report calculations of the phases and phase diagram for superfluid 3He in thin films using a strong-coupling Ginzburg-Landau theory that accurately reproduces the bulk 3He superfluid phase diagram. We find that the stability of the Stripe phase is diminished relative to the A phase, but the Stripe phase is stable in a large range of temperatures, pressures, confinement, and surface conditions.

  9. Recurring 3He-rich Solar Energetic Particle Events

    CERN Document Server

    Bucik, R; Mall, U; Korth, A; Mason, G M

    2013-01-01

    Using the SIT instrument aboard STEREO we have examined the abundance of the 3He during the ascending phase of solar cycle 24 from January 2010 through December 2012. We report on several cases when 3He-rich solar energetic particle events were successively observed on ACE and STEREO-A with delays consistent with the Carrington rotation rate. In the investigated period ACE and STEREO-A were significantly separated in the heliolongitude corresponding to solar rotation times of 5 to 10 days. We inspect STEREO-A EUV images and use the potential-field source-surface extrapolations together with in-situ magnetic field data to identify responsible solar sources. We find the 3He/4He ratio highly variable in these events and correlated between the spacecraft for the cases with the same connection region on the Sun.

  10. Ultrasensitive 3He magnetometer for measurements of high magnetic fields

    CERN Document Server

    Nikiel, A; Heil, W; Hehn, M; Karpuk, S; Maul, A; Otten, E; Schreiber, L M; Terekhov, M

    2014-01-01

    We describe a 3He magnetometer capable to measure high magnetic fields (B > 0.1 Tesla) with a relative accuracy of better than 10^-12. Our approach is based on the measurement of the free induction decay of gaseous, nuclear spin polarized 3He following a resonant radio frequency pulse excitation. The measurement sensitivity can be attributed to the long coherent spin precession time T2* being of order minutes which is achieved for spherical sample cells in the regime of motional narrowing where the disturbing influence of field inhomogeneities is strongly suppressed. The 3He gas is spin polarized in-situ using a new, non-standard variant of the metastability exchange optical pumping. We show that miniaturization helps to increase T2* further and that the measurement sensitivity is not significantly affected by temporal field fluctuations of order 10^-4.

  11. Anisotropic phases of superfluid ^{3}he in compressed aerogel.

    Science.gov (United States)

    Li, J I A; Zimmerman, A M; Pollanen, J; Collett, C A; Halperin, W P

    2015-03-13

    It has been shown that the relative stabilities of various superfluid states of ^{3}He can be influenced by anisotropy in a silica aerogel framework. We prepared a suite of aerogel samples compressed up to 30% for which we performed pulsed NMR on ^{3}He imbibed within the aerogel. We identified A and B phases and determined their magnetic field-temperature phase diagrams as a function of strain. From these results, we infer that the B phase is distorted by negative strain forming an anisotropic superfluid state more stable than the A phase.

  12. Rotational quenching of CS in ultracold 3He collisions

    Science.gov (United States)

    Kaur, Rajwant; Dhilip Kumar, T. J.

    2016-08-01

    Quantum mechanical scattering calculations of rotational quenching of CS (v = 0) collision with 3He are performed at ultracold temperatures and results are compared with isotopic 4He collision. Rotational quenching cross sections and rate coefficients have been calculated in the ultracold region for rotational levels up to j = 10 using the He-CS potential energy surface computed at the CCSD(T)/aug-cc-pVQZ level of theory. The quenching cross sections are found to be two orders of magnitude larger for the 3He than the 4He isotope under ultracold conditions. Wigner threshold law is found to be valid below 10-3 K temperature.

  13. A measurement of the Panofsky ratio in 3He

    International Nuclear Information System (INIS)

    The nucleus 3He is one of the simplest nuclear systems; hence it is often used to study the complications introduced by the presence of additional nucleons on basic processes such as pion absorption on a free nucleon. 3He is the only nucleus for which both the pion charge exchange and radiative capture processes can occur at rest with reasonable probability. The ratio of these two processes is the well-known Panofsky ratio, P3 = ω(π-3He→π0T)/ω(π-+3He→γT). (orig./WL)

  14. 3He-MRI of pulmonary ventilation: First clinical applications

    International Nuclear Information System (INIS)

    Purpose of the study is the visualisation of normal pulmonary ventilation in healthy volunteers and the evaluation of abnormalities in patients with different lung diseases using 3He magnetic resonance imaging (3He-MRI). Material und methods: Hyperpolarised 3He gas (V=300 ml, p=3x105 Pa, polarised to 35-45% by optical pumping, provided in special glass cells) was inhaled by eight healthy volunteers and ten patients with different lung diseases. A 3 D FLASH sequence (TR=11.8 ms; TE=5 ms; matrix 144x256, FOV 350 mm, section thickness 7-10 mm, coronal orientation) was performed in a single breath-hold (22-42 s). Clinical and radiological examinations were available for correlation. Results: The studies were successfully carried out in 8/8 volunteers and in 8/10 patients. The central airways were constantly visualised with intermediate to high signal instensity. The lung parenchyma of volunteers with normal ventilatory function showed rather homogeneous intermediate to high signal, whereas patients with chronic abstructive lung disease and/or pneumonia presented severe signal inhomogeneitises. Space-occupying lesions and pleural effusion caused large areas with little or no signal. The represented the lesion and adjacent ventilatory disturbances whose extent had not been presumed from chest X-ray or CT. The spatial resolution was higher than in ventilation scintigraphy. Conclusion: 3He MRI is a promising new modality for the assessment of pulmonary ventilation and its anormalies. (orig.)

  15. Theoretical description of deeply virtual Compton scattering off $^3$He

    CERN Document Server

    Rinaldi, Matteo

    2014-01-01

    Recently, coherent deeply virtual Compton scattering (DVCS) off $^3$He nuclei has been proposed to access the neutron generalized parton distributions (GPDs). In Impulse Approximation (IA) studies, it has been shown, in particular, that the sum of the two leading twist, quark helicity conserving GPDs of $^3$He, $H$ and $E$, at low momentum transfer, is dominated by the neutron contribution, so that $^3$He is very promising for the extraction of the neutron information. Nevertheless, such an extraction could be not trivial. A technique, able to take into account the nuclear effects included in the IA analysis in the extraction procedure, has been therefore developed. In this work, the IA calculation of the spin dependent GPD $\\tilde H$ of $^3$He is presented for the first time. This quantity is found to be largely dominated, at low momentum transfer, by the neutron contribution, which could be extracted using arguments similar to the ones previously proposed for the other GPDs. The known forward limit of the I...

  16. The {sup 3}He neutron-spin filter at ILL

    Energy Technology Data Exchange (ETDEWEB)

    Tasset, F.; Heil, W.; Humblot, H.; Lelievre-Berna, E.; Roberts, T. [Institut Max von Laue - Paul Langevin (ILL), 38 - Grenoble (France)

    1997-04-01

    Neutron-Spin Filters (NSF) using gaseous polarised {sup 3}He have long been recognised as of enormous potential value in many polarised neutron-scattering applications and, accordingly, ILL started a development programme some years ago. This report gives an account of the present status of the project. (author). 13 refs.

  17. Conceptual design of the D- sup 3 He reactor artemis

    Energy Technology Data Exchange (ETDEWEB)

    Momoto, H.; Tomita, Y. (National Inst. for Fusion Science, Nagoya (JP)); Ishida, A. (Niigata Univ. (Japan)); Miley, G.H. (Illinois Univ., Urbana, IL (United States)); Kohzaki, Y. (Inst. for Future Technology, Tokyo (JP)); Ohi, S. (Osaka Univ., Suita (Japan)); Ohnishi, M. (Kyoto Univ. (Japan)); Sato, H. (Himeji Inst. of Tech., Hyogo (Japan)); Steinhauer, L.C. (STI Optronics, Inc., Bellevue, WA (US)); Tuszewski, M. (Los Alamos National Lab., NM (United States))

    1992-07-01

    In this paper, a comprehensive design study of the D-{sup 3}He-fueled field-reversed configuration (FRC) reactor Artemis is carried out for the purpose of proving its attractive characteristics and clarifying the critical issues for a commercial fusion reactor. The FRC burning plasma is stabilized and sustained in a steady equilibrium by means of preferential trapping of D-{sup 3}He fusion-produced energetic protons. A novel direct energy converter for 15-MeV protons is also presented. On the basis of consistent fusion plasma production and simple engineering, a compact and simple reactor concept is presented. The D-{sup 3}He FRC power plant offers a most attractive prospect for energy development. It is environmentally acceptable in terms of radioactivity and fuel resources, and the estimated cost of electricity is low compared with a light water reactor. Critical physics and engineering issues in the development of the D-{sup 3}He FRC reactor are clarified.

  18. Depth profiling of deuterium with the D(3He,p)4He reaction

    International Nuclear Information System (INIS)

    The use of the nuclear reaction D(3He,p)4He for the depth profiling of deuterium was studied. The detection at backward angles of the protons which have energies in excess of 13 MeV, presents distinct advantages with respect to the more conventional method of detecting the associated α particles. The various contributions to the depth resolution in α-Si have been measured or calculated, taking into account detector acceptance angle, size of the probing 3He beam, energy straggling, multiple scattering and lateral spread contributions. Sensitivities are discussed with respect to depth resolution requirements. The method has been applied to deuterium depth profiling in amorphous silicon hydrogenated by implantation or plasma diffusion of deuterium. (orig.)

  19. Surface Scattering Effect and the Stripe Order in Films of the Superfluid 3He B Phase

    Science.gov (United States)

    Aoyama, Kazushi

    2016-09-01

    Surface scattering effects in thin films of the superfluid 3He B phase have been theoretically investigated, with an emphasis on the stability of the stripe order with spontaneous broken translational symmetry in the film plane and quasiparticle excitations in this spatially inhomogeneous phase. Based on the Ginzburg-Landau theory in the weak coupling limit, we have shown that the stripe order, which was originally discussed for a film with two specular surfaces, can be stable in a film with one specular and one diffusive surfaces which should correspond to superfluid 3He on a substrate. It is also found by numerically solving the Eilenberger equation that due to the stripe structure, a midgap state distinct from the surface Andreev bound state emerges and its signature is reflected in the local density of states.

  20. Magnetic resonance imaging in children with sickle cell disease - detecting alterations in the apparent diffusion coefficient in hips with avascular necrosis

    Energy Technology Data Exchange (ETDEWEB)

    MacKenzie, John D. [Children' s Hospital of Philadelphia, Department of Pediatric Radiology, Philadelphia, PA (United States); UCSF Benioff Children' s Hospital, Department of Radiology and Biomedical Imaging, San Francisco, CA (United States); Hernandez, Andrea; Pena, Andres; Khrichenko, Dmitry; Gonzalez, Leonardo; Jaramillo, Diego [Children' s Hospital of Philadelphia, Department of Pediatric Radiology, Philadelphia, PA (United States); Ruppert, Kai [Children' s Hospital of Philadelphia, Department of Pediatric Radiology, Philadelphia, PA (United States); University of Virginia, Department of Radiology, Charlottesville, VA (United States); Jawad, Abbas F. [Children' s Hospital of Philadelphia, Department of Pediatrics, Philadelphia, PA (United States); Wells, Lawrence [Children' s Hospital of Philadelphia, Department of Orthopedics, Philadelphia, PA (United States); Smith-Whitley, Kim [Children' s Hospital of Philadelphia, Department of Hematology, Philadelphia, PA (United States)

    2012-06-15

    Avascular necrosis (AVN) is a common morbidity in children with sickle cell disease (SCD) that leads to pain and joint immobility. However, the diagnosis is often uncertain or delayed. To examine the ability of apparent diffusion coefficient (ADC) measurements on diffusion-weighted imaging to detect AVN in children with SCD. ADC values were calculated at the hips of normal children (n = 19) and children with SCD who were either asymptomatic with no known previous hip disease (n = 13) or presented for the first time with clinical symptoms of hip pathology (n = 12). ADC values were compared for differences among groups with and without AVN using non-parametric statistical methods. The ADC values were elevated in the hips of children with AVN (median ADC = 1.57 x 10{sup -3} mm{sup 2}/s [95% confidence interval = 0.86-2.10]) and differed significantly in pairwise comparisons (all P < 0.05) from normal children (0.74 [0.46-0.98]), asymptomatic children with SCD (0.55 [0.25-0.85]), and SCD children who had symptoms referable to their hips but did not show findings of hip AVN on conventional MRI or radiographs (0.46 [0.18-0.72]). Children with sickle cell disease have elevated apparent diffusion coefficient values in their affected hips on initial diagnosis of avascular necrosis. (orig.)

  1. Functional {sup 3}He-MRI of the lungs; Funktionelle {sup 3}He-MRT der Lunge

    Energy Technology Data Exchange (ETDEWEB)

    Gast, K.K.; Wolf, U. [Universitaetsmedizin der Johannes-Gutenberg-Universitaet Mainz, Klinik und Poliklinik fuer Diagnostische und Interventionelle Radiologie, Mainz (Germany)

    2009-08-15

    Pulmonary diseases have a high health-related and economic significance. {sup 3}He-MRI is an alternative imaging method which can detect ventilatory disturbances with a high sensitivity. The application of different pulse sequences allows static and dynamic assessment of ventilation and bronchial gas flow, non-invasive measurement of intrapulmonary oxygen partial pressure and quantification of pulmonary parenchyma destruction and overinflation. Generally, the method is applicable for obstructive and restrictive ventilatory disturbances but initial approaches also exist for vascular pulmonary diseases. Specific clinical applications remain to be determined but {sup 3}He-MRI is an excellent instrument for the assessment of physiologic and pathophysiologic interrelations in the distribution of ventilation. (orig.) [German] Lungenerkrankungen haben einen hohen gesundheitlichen und volkswirtschaftlichen Stellenwert. Die {sup 3}He-MRT ist eine alternative bildgebende Methode, die sensitiv Ventilationsstoerungen nachweisen kann. Ueber unterschiedliche Pulssequenzen koennen Ventilation und Gasfluesse statisch und dynamisch dargestellt, der intrapulmonale Sauerstoffpartialdruck nichtinvasiv gemessen und die Destruktion und Ueberblaehung des Lungenparenchyms quantifiziert werden. Prinzipiell ist die Methode fuer die Untersuchung obstruktiver und restriktiver Ventilationsstoerungen anwendbar, Ansaetze existieren jedoch auch fuer vaskulaere Lungenerkrankungen. Spezifische klinische Anwendungen fuer die {sup 3}He-MRT muessen noch erarbeitet werden, sie ist jedoch ein hervorragendes Instrument zur Untersuchung physiologischer und pathophysiologischer Zusammenhaenge bei der Ventilationsverteilung. (orig.)

  2. Nuclear (K) Bound States in 4He and 3He

    Institute of Scientific and Technical Information of China (English)

    LI Yi-He; WU Shi-Shu

    2009-01-01

    @@ We construct a phenomenological K N interaction which reproduces the two resonances: the energy of the first resonance is 1420MeV and the other is 1392MeV. The A(1405) is found by a superposition of the two reso-nances with appropriate weights. Within the framework of the Brueckner-Hartree-Fock theory, we have studied K- - 3He(T=0) and K- - 4He(T=1/2). The binding energy BK-is 93MeV(72MeV) and the width F is 13 MeV(25 MeV) for K- - 3He(T=0) (K- - 4He(T=1/2)).

  3. Photoassociation spectroscopy of ultracold metastable ^3He dimers

    CERN Document Server

    Cocks, Daniel G; Whittingham, Ian B

    2011-01-01

    The bound states of the fermionic ^3He(2 ^3S_1)+ ^3He(2 ^3P_j)system, where j=0,1,2, are investigated using the recently available ab initio short-range ${}^{1,3,5}\\Sigma^{+}_{g,u}$ and ${}^{1,3,5}\\Pi_{g,u}$ potentials computed by Deguilhem et al. (J. Phys. B: At. Mol. Opt. Phys., 2009, 42, 015102). Single-channel and multichannel calculations have been undertaken in order to investigate the effects of Coriolis and non-adiabatic couplings. The possible experimental observability of the theoretical levels is assessed using criteria based upon the short-range character of each level and their coupling to metastable ground states. Purely long-range levels have been identified and 30 short-range levels near five asymptotes are suggested for experimental investigation.

  4. Studies of 3He Induced Nuclear Reactions on Cadmium

    International Nuclear Information System (INIS)

    Excitation functions of 3He induced nuclear reactions on natural cadmium were measured using the standard stacked foil technique and high resolution gamma ray spectroscopy. The experimental cross sections for the nuclear reactions natCd(3He,xnp )117m,g,116m115m,114m,113m,111,110m,g,109,108,107 In were measured from their threshold energy up to 27 MeV. The integral yields for some medically important products were determined. Theoretical calculations using the nuclear codes ALICE- IPPE, TAL YS, and EMPIRE-3 were used to describe the formation of these products. Theoretical and experimental results were compared with each other. K

  5. A polarized sup 3 He internal target for storage rings

    CERN Document Server

    Poolman, H R; Bulten, H J; Doets, M; Ent, R; Ferro-Luzzi, M; Geurts, D G; Harvey, M; Mul, F A

    2000-01-01

    A polarized sup 3 He internal target was employed at the internal target facility of the Amsterdam electron Pulse Stretcher and Storage ring (AmPS) at the Dutch National Institute for Nuclear and High-Energy Physics (NIKHEF). The unique features of internal targets such as chemical and isotopic purity, high and rapidly reversible polarization, and the ability to manipulate the target spin orientation were successfully demonstrated. A nuclear polarization of 0.50 (0.42) at a sup 3 He gas flow of 1.0 (2.0)x10 sup 1 sup 7 at s sup - sup 1 could be obtained. Operation at a nominal flow of 1x10 sup 1 sup 7 at s sup - sup 1 resulted in a target thickness of 0.7x10 sup 1 sup 5 at cm sup - sup 2 at a target temperature of 17 K.

  6. Hard Two-body Photodisintegration of 3He

    CERN Document Server

    Pomerantz, I; Gilman, R; Higinbotham, D W; Piasetzky, E; Strauch, S; Adhikari, K P; Aghasyan, M; Allada, K; Amaryan, M J; Pereira, S Anefalos; Anghinolfi, M; Baghdasaryan, H; Ball, J; Baltzell, N A; Battaglieri, M; Batourine, V; Beck, A; Beck, S; Bedlinskiy, I; Berman, B L; Biselli, A S; Boeglin, W; Bono, J; Bookwalter, C; Boiarinov, S; Briscoe, W J; Brooks, W K; Bubis, N; Burkert, V; Camsonne, A; Canan, M; Carman, D S; Celentano, A; Chandavar, S; Charles, G; Chirapatpimol, K; Cisbani, E; Cole, P L; Contalbrigo, M; Crede, V; Cusanno, F; D'Angelo, A; Daniel, A; Dashyan, N; de Jager, C W; De Vita, R; De Sanctis, E; Deur, A; Djalali, C; Dodge, G E; Doughty, D; Dupre, R; Dutta, C; Egiyan, H; Alaoui, A El; Fassi, L El; Eugenio, P; Fedotov, G; Fegan, S; Fleming, J A; Fradi, A; Garibaldi, F; Geagla, O; Gevorgyan, N; Giovanetti, K L; Girod, F X; Glister, J; Goetz, J T; Gohn, W; Golovatch, E; Gothe, R W; Griffioen, K A; Guegan, B; Guidal, M; Guo, L; Hafidi, K; Hakobyan, H; Harrison, N; Heddle, D; Hicks, K; Ho, D; Holtrop, M; Hyde, C E; Ireland, D G; Ishkhanov, B S; Isupov, E L; Jiang, X; Jo, H S; Joo, K; Katramatou, A T; Keller, D; Khandaker, M; Khetarpal, P; Khrosinkova, E; Kim, A; Kim, W; Klein, F J; Koirala, S; Kubarovsky, A; Kubarovsky, V; Kuleshov, S V; Kvaltine, N D; Lee, B; LeRose, J J; Lewis, S; Lindgren, R; Livingston, K; Lu, H Y; MacGregor, I J D; Mao, Y; Martinez, D; Mayer, M; McCullough, E; McKinnon, B; Meekins, D; Meyer, C A; Michaels, R; Mineeva, T; Mirazita, M; Moffit, B; Mokeev, V; Montgomery, R A; Moutarde, H; Munevar, E; Camacho, C Munoz; Nadel-Turonski, P; Nasseripour, R; Nepali, C S; Niccolai, S; Niculescu, G; Niculescu, I; Osipenko, M; Ostrovidov, A I; Pappalardo, L L; Paremuzyan, R; Park, K; Park, S; Petratos, G G; Phelps, E; Pisano, S; Pogorelko, O; Pozdniakov, S; Procureur, S; Protopopescu, D; Puckett, A J R; Qian, X; Qiang, Y; Ricco, G; Rimal, D; Ripani, M; Ritchie, B G; Rodriguez, I; Ron, G; Rosner, G; Rossi, P; Sabatie, F; Saha, A; Saini, M S; Sarty, A J; Sawatzky, B; Saylor, N A; Schott, D; Schulte, E; Schumacher, R A; Seder, E; Seraydaryan, H; Shneor, R; Smith, G D; Sokhan, D; Sparveris, N; Stepanyan, S S; Stepanyan, S; Stoler, P; Subedi, R; Sulkosky, V; Taiuti, M; Tang, W; Taylor, C E; Tkachenko, S; Ungaro, M; Vernarsky, B; Vineyard, M F; Voskanyan, H; Voutier, E; Walford, N K; Wang, Y; Watts, D P; Weinstein, L B; Weygand, D P; Wojtsekhowski, B; Wood, M H; Yan, X; Yao, H; Zachariou, N; Zhan, X; Zhang, J; Zhao, Z W; Zheng, X; Zonta, I

    2013-01-01

    We have measured cross sections for the gamma+3He->p+d reaction at photon energies of 0.4 - 1.4 GeV and a center-of-mass angle of 90 deg. We observe dimensional scaling above 0.7 GeV at this center-of-mass angle. This is the first observation of dimensional scaling in the photodisintegration of a nucleus heavier than the deuteron.

  7. Orbital angular momentum in /sup 3/He-A-italic

    Energy Technology Data Exchange (ETDEWEB)

    Balatskii-breve, A.V.; Mineev, V.P.

    1985-12-01

    The intrinsic angular momentum in the A-italic phase of superfluid /sup 3/He is found in terms of the response to the angular velocity of rotation. It is shown that in the weak-coupling approximation at an arbitrary temperature and with allowance for the Fermi-liquid renormalization the intrinsic angular momentum is small in accordance with the smallness of the asymmetry in the distribution of particles and holes.

  8. Hard Photodisintegration of 3He into pd pair

    CERN Document Server

    Maheswari, Dhiraj

    2016-01-01

    The recent measurements of high energy photodisintegration of the $^3He$ nucleus to the $pd$ pair at $90^0$ center of mass demonstrated an energy scaling consistent with the quark counting rule with unprecedentedly large exponent of $s^{-17}$. To understand the underlying mechanism of this process we extended the theoretical formalism of hard rescattering mechanism to calculate the $\\gamma ^3He\\rightarrow pd$ reaction. In HRM the incoming high energy photon strikes a quark from one of the nucleons in the target which subsequently undergoes hard rescattering with the quarks from the other nucleons generating hard two-body system in the final state of the reaction. Within the HRM we derived the parameter free expression for the differential cross section of the reaction, which is expressed through the $^3He\\rightarrow pd$ transition spectral function, cross section of hard $pd\\rightarrow pd$ scattering and the effective charge of the quarks being interchanged during the hard rescattering process. The numerical ...

  9. High Efficiency Spin Flipper for the n3He Experiment

    Science.gov (United States)

    Hayes, Christopher; n3He Collaboration

    2015-10-01

    The n3He experiment, constructed on the Fundamental Neutron Physics Beamline (FnPB) at the Spallation Neutron Source, is designed to measure the parity violating (PV) proton asymmetry Ap in the capture reaction n +3 He -->3 H + p + 765 keV The asymmetry has an estimated value Ap ~ - 1 ×10-7 and is directly related to the weak isospin conserved couplings hρ0 and ωρ0 which are of fundamental interest in the verification of the meson exchange model of low energy NN intereactions. Data production for the n3He experiment began in February 2015 and is scheduled to continue thru December 2015 - reaching a statistical sensitivity δAp ~10-8 or better. I will discuss the spin flipper which is designed using the theory of double cosine-theta coils, and capable of flipping neutron spins with an efficiency approaching its maximum value ɛsf = 1 . I will also discuss the theory of Spin Magnetic Resonance (SMR) and how it is employed by the spin flipper to flip 60 Hz pulses of cold neutrons over a range of wavelengths.

  10. Search for 3He and 4He in Arata-Style Palladium Cathodes I: A Negative Result

    International Nuclear Information System (INIS)

    The 3He and 4He concentrations in 2- to 6-mg samples of palladium-black from the interior of Arata-style cathodes were investigated using a tungsten wire furnace on-line to an ultrahigh sensitivity static mass spectrometer. The detection limit of the mass spectrometer was ∼104 atoms 3He and 108 atoms 4He, and the mass resolution of 1 part in 620 was sufficient to cleanly resolve 3He from H3 and HD. Three specimens of palladium-black (A, B, and C) were from hollow Pd cathodes that had generated excess heat in D2O electrolysis experiments carried out by Arata and Zhang in their laboratory. One specimen of Pd-black (D) had not been used in any electrolysis experiment. A total of twelve samples, three from each specimen, were analyzed. The 3He and 4He concentrations were variable as if due to sample inhomogeneity. Two samples (C-1 and B-1) showed apparent 4He of 4.4 x 109 atoms/mg and 6.6 x 109 atoms/mg, respectively, and three (A-3, B-2, and D-3) showed excess 3He from 77 to 1096 x 103 atoms/mg relative to the atmospheric 3He/4He ratio. Seven samples showed no apparent excess of 3He or 4He. Five samples of the aluminum foil used to wrap Pd-black samples were also analyzed and gave mean values of 13 ± 18 x 103 atoms/mg and 1.50 ± 0.66 x 109 atoms/mg for 3He and 4He, respectively. The values for Al and Pd-black are comparable to the 1978 results of Mamyrin, Khabarin, and Yudenich, who examined helium isotopes in many ordinary metals and other materials including Al and Pd. At present, there is no evidence for the very much larger concentrations (1016 to 1017 atoms/mg) of 3He and 4He that Arata and Zhang claim to have detected in similar specimens of Pd-black from Pd cathodes subjected to D2O electrolysis

  11. Apparent diffusion coefficient measurements of bilateral kidneys at 3 T MRI: Effects of age, gender, and laterality in healthy adults

    International Nuclear Information System (INIS)

    Aim: To investigate the effects of age and gender on apparent diffusion coefficient (ADC) measurements of bilateral kidneys at 3 T MRI, and compare the ADC values of left and right kidneys. Materials and methods: In all, 137 healthy participants (mean age 42.8 ± 14.7 years; age range 16–75 years) comprising 68 male and 69 female participants were enrolled. Three Tesla echo-planar diffusion-weighted imaging (DWI) of bilateral kidneys was performed and ADC values were measured in the cortex, medulla, and whole parenchyma. Pearson correlation analysis and linear regression were performed to determine the associations between the ADC values in each region and age. Effects of age and gender on ADC values were analysed using two-factor analysis of variance (ANOVA). The paired-samples t-test was established to compare the ADC values between left and right kidneys. Results: ADC values were significantly higher in the young group (≤50 years) than in the old group (>50 years), and correlated inversely with the age in all regions. Male participants had higher ADC values than female participants in all regions except left medulla. Two-factor ANOVA of age × gender showed no significant interactions between the variables age and gender were found. No significant differences in ADC values between left and right kidneys were observed. Conclusion: Renal ADC values are age- and gender-dependent, and show no significant difference between left and right kidneys. Age- and gender-related effects should be taken into consideration in future renal DWI studies when using normal ADC values from health controls. - Highlights: • Renal apparent diffusion coefficient (ADC) values decrease with ageing. • Men tend to have higher renal ADC values than women. • Bilateral kidneys seem to have no significantly different ADC values

  12. Evolution of Apparent Diffusion Coefficient and Fractional Anisotropy in the Cerebrum of Asphyxiated Newborns Treated with Hypothermia over the First Month of Life

    Directory of Open Access Journals (Sweden)

    Saskia Kwan

    2015-01-01

    Full Text Available The objective of this study was to assess the evolution of diffusion-weighted imaging (DWI and diffusion-tensor imaging (DTI over the first month of life in asphyxiated newborns treated with hypothermia and to compare it with that of healthy newborns. Asphyxiated newborns treated with hypothermia were enrolled prospectively; and the presence and extent of brain injury were scored on each MRI. Apparent diffusion coefficient (ADC and fractional anisotropy (FA values were measured in the basal ganglia, in the white matter and in the cortical grey matter. Sixty-one asphyxiated newborns treated with hypothermia had a total of 126 ADC and FA maps. Asphyxiated newborns developing brain injury eventually had significantly decreased ADC values on days 2-3 of life and decreased FA values around day 10 and 1 month of life compared with those not developing brain injury. Despite hypothermia treatment, asphyxiated newborns may develop brain injury that still can be detected with advanced neuroimaging techniques such as DWI and DTI as early as days 2-3 of life. A study of ADC and FA values over time may aid in the understanding of how brain injury develops in these newborns despite hypothermia treatment.

  13. Vortex clusters in superfluid 3He-B

    International Nuclear Information System (INIS)

    A unique property of 3He-B is vortex-free rotation, due to a high nucleation threshold of the singular vortices. In contrast to other superfluids, rotational states consisting of a vortex cluster surrounded by vortex-free counterflow form spontaneously and can also be prepared with a fixed number of vortices. The clusters can be analyzed by means of NMR measurements with high precision. These techniques have been exploited to study rotational states in the presence of different phase boundaries. (orig.)

  14. The 3H-3He Charge Radii Difference

    Energy Technology Data Exchange (ETDEWEB)

    Myers, Luke S. [Bluffton University, Bluffton, OH; Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Arrington, John R. [Argonne National Lab. (ANL), Argonne, IL (United States); Higinbotham, Douglas W. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-03-01

    The upcoming E12-14-009 [1] experiment at Jefferson Lab will determine the ratio of the electric form factors for the A=3 mirror nuclei 3He and 3H. The measurement will use a 1.1 GeV electron beam, a special collimator plate to allow for simultaneous optics measurements, and the low-activity tritium target being prepared for Jefferson Lab. By observing the dependence of the form factor ratio as a function of Q2 over 0.05–0.09 GeV2, the dependence of the radii extraction on the shape of the form factors is minimized. As a result, we anticipate the uncertainty of the extracted charge radii difference to be 0.03 fm, a reduction of 70% from the current measurement. Using precise measurements of the 3He charge radius from isotopic shift or μHe measurements [2–4], we can deduce the absolute 3H charge radius. The results will provide a direct comparison to recent calculations of the charge radii.

  15. Neutron scattering from liquid {sup 3}He at intermediate energies

    Energy Technology Data Exchange (ETDEWEB)

    Guckelsberger, K. [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany); Azuah, R.T. [Department of Physics, Keele University, Keele Staffordshire, ST5 5BG (United Kingdom)]|[Rutherford Appleton Laboratory, Chilton, Didcot, Oxon, OX11 0Qx (United Kingdom); Stirling, W.G. [Keele University (United Kingdom); Bennington, S.M.; Yates, M. [Rutherford Appleton Laboratory, Chilton, Didcot, Oxon, OX11 0Qx (United Kingdom)

    1997-06-01

    Understanding the dynamics of strongly interacting quantum liquids is at the heart of much of contemporary physics and the archetypal Fermi liquid is {sup 3}He at low temperatures. However, due to the enormous absorption of neutrons by {sup 3}He, experiments are exceedingly difficult. At very high incident neutron energies (>1 eV), the struck atoms behave as if they were free. In a sense, one can ``switch on the interaction`` by using neutrons with ever lower energies until they are-near 1 meV-comparable to that of the interaction. In the present work we use 80-400 meV neutrons to resolve a long standing puzzle: previous measurements suggested strong fluctuations in the width of the recoil peak that could not be understood in terms of a simple theory. Using improved instrumentation (MARI at the spallation source) and novel sample cell design we could improve statistics by more than one order of magnitude. The new data covering an extended energy range are presented and seem to confirm the theory. (orig.).

  16. Hard photodisintegration of a proton pair in {sup 3}He

    Energy Technology Data Exchange (ETDEWEB)

    Stanley Brodsky; Leonid Frankfurt; Ronald Gilman; J. R. Hiller; G. A. Miller; Eliezer Piasetzky; Misak Sargsian; Mark Strikman

    2003-05-01

    Hard photodisintegration of the deuteron has been extensively studied in order to understand the dynamics of the transition from hadronic to quark-gluon descriptions of the strong interaction. In this work, we discuss the extension of this program to hard photodisintegration of a pp pair in the {sup 3}He nucleus. Experimental confirmation of new features predicted here for the suggested reaction would advance our understanding of hard nuclear reactions. A main prediction, in contrast with low-energy observations, is that the pp breakup cross section is not much smaller than the one for pn break up. In some models, the energy-dependent oscillations observed for pp scattering are predicted to appear in the {gamma} {sup 3}He {yields} pp + n reaction. Such an observation would open up a completely new field in studies of color coherence phenomena in hard nuclear reactions. We also demonstrate that, in addition to the energy dependence, the measurement of the light-cone momentum distribution of the recoil neutron provides an independent test of the underlying dynamics of hard disintegration.

  17. Intercomparison of tritium and noble gases analyses, 3H/3He ages and derived parameters excess air and recharge temperature

    International Nuclear Information System (INIS)

    Highlights: • Key results of the groundwater age-dating interlaboratory comparison exercise. • The reproducibility of the tritium measurements was 13.5%. • The noble gas reproducibility was <2% (R, He, Ne) and <3% (Ar, Kr, Xe). • The measurement uncertainty meets the requirements for 3H/3He dating. • Other sources of uncertainty are less well defined than the analytical uncertainty. - Abstract: Groundwater age dating with the tritium–helium (3H/3He) method has become a powerful tool for hydrogeologists. The uncertainty of the apparent 3H/3He age depends on the analytical precision of the 3H measurement and the uncertainty of the tritiogenic 3He component. The goal of this study, as part of the groundwater age-dating interlaboratory comparison exercise, was to quantify the analytical uncertainty of the 3H and noble gas measurements and to assess whether they meet the requirements for 3H/3He dating and noble gas paleotemperature reconstruction. Samples for the groundwater dating intercomparison exercise were collected on 1 February, 2012, from three previously studied wells in the Paris Basin (France). Fourteen laboratories participated in the intercomparison for tritium analyses and ten laboratories participated in the noble gas intercomparison. Not all laboratories analyzed samples from every borehole. The reproducibility of the tritium measurements was 13.5%. The reproducibility of the 3He/4He ratio and 4He, Ne, Ar, Kr and Xe concentrations was 1.4%, 1.8%, 1.5%, 2.2%, 2.9%, and 2.4% respectively. The uncertainty of the tritium and noble gas measurements results in a typical 3H/3He age precision of better than 2.5 years in this case. However, the measurement uncertainties for the noble gas concentrations are insufficient to distinguish the appropriate excess air model if the measured helium concentration is not included. While the analytical uncertainty introduces an unavoidable source of uncertainty in the 3H/3He apparent age estimate, other sources of

  18. Effects of gender, age, and body mass index on fat contents and apparent diffusion coefficients in healthy parotid glands: an MRI evaluation

    International Nuclear Information System (INIS)

    To establish standard apparent diffusion coefficient (ADC) and the fat content as a function of age, gender and body mass index (BMI) in healthy parotid glands, and to address the influences of fat suppression on ADC measurements. A total of 100 healthy adults (gender and age evenly distributed) were prospectively recruited, with parotid fat content measured from gradient-echo images with fat-water separated using iterative decomposition with echo asymmetry and least squares (IDEAL). The ADCs were estimated using both fat-saturated and non-fat-saturated diffusion-weighted imaging via a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) technique. Parotid fat content was larger in men than in women by about 10 percentage points (P < 0.005), and positively associated with BMI and age for both genders (mostly with P < 0.001). ADCs estimated with non-fat-saturated PROPELLER were significantly lower in men than in women (P < 0.005), but showed no gender difference if measured using fat-saturated PROPELLER (P = 0.840). The negative association between parotid ADC and age/BMI/fat (P < 0.001) showed greater regression slopes in non-fat-saturated PROPELLER than in fat-saturated data. Parotid fat content in healthy adults correlates positively with both age and BMI; the correlation with age is gender-dependent. Parotid ADC measurements are strongly influenced by fat saturation. (orig.)

  19. Effects of gender, age, and body mass index on fat contents and apparent diffusion coefficients in healthy parotid glands: an MRI evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Hing-Chiu [National Taiwan University, Graduate Institute of Biomedical Electronics and Bioinformatics, Taipei (China); Duke University Medical Center, Brain Imaging and Analysis Center, Durham, NC (United States); GE Healthcare, Applied Science Laboratory, Taipei (China); Juan, Chun-Jung; Hsu, Hsian-He [National Defense Medical Center, Department of Radiology, Taipei (China); Tri-Service General Hospital, Department of Radiology, Taipei (China); Chiu, Hui-Chu [Tatung University, Graduate Institute of Design Science, Taipei (China); Cheng, Cheng-Chieh; Chiu, Su-Chin [National Taiwan University, Graduate Institute of Biomedical Electronics and Bioinformatics, Taipei (China); Liu, Yi-Jui [Feng Chia University, Department of Automatic Control Engineering, Taichung (China); Chung, Hsiao-Wen [National Taiwan University, Graduate Institute of Biomedical Electronics and Bioinformatics, Taipei (China); Tri-Service General Hospital, Department of Radiology, Taipei (China); National Taiwan University, MD.624, Department of Electrical Engineering, Taipei (China)

    2014-09-15

    To establish standard apparent diffusion coefficient (ADC) and the fat content as a function of age, gender and body mass index (BMI) in healthy parotid glands, and to address the influences of fat suppression on ADC measurements. A total of 100 healthy adults (gender and age evenly distributed) were prospectively recruited, with parotid fat content measured from gradient-echo images with fat-water separated using iterative decomposition with echo asymmetry and least squares (IDEAL). The ADCs were estimated using both fat-saturated and non-fat-saturated diffusion-weighted imaging via a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) technique. Parotid fat content was larger in men than in women by about 10 percentage points (P < 0.005), and positively associated with BMI and age for both genders (mostly with P < 0.001). ADCs estimated with non-fat-saturated PROPELLER were significantly lower in men than in women (P < 0.005), but showed no gender difference if measured using fat-saturated PROPELLER (P = 0.840). The negative association between parotid ADC and age/BMI/fat (P < 0.001) showed greater regression slopes in non-fat-saturated PROPELLER than in fat-saturated data. Parotid fat content in healthy adults correlates positively with both age and BMI; the correlation with age is gender-dependent. Parotid ADC measurements are strongly influenced by fat saturation. (orig.)

  20. MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter.

    Science.gov (United States)

    Sijens, P E; Fock, J M; Meiners, L C; Potze, J H; Irwan, R; Oudkerk, M

    2007-06-01

    Brain magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) in one patient with merosin-deficient congenital muscular dystrophy (MDCMD) revealed significant metabolite (choline, creatine, N-acetyl aspartate) level reductions, fractional anisotropy (FA) reduction and increased apparent diffusion coefficient (ADC) in the white matter (p<0.01, all). In the gray matter, the MRS properties did not differ significantly from those in controls. The ADC and FA, however, differed significantly as in the white matter, although the differences were less pronounced. This is the first quantitative MR study of the brain in a patient with MDCMD, which revealed that the concentrations of all MRS measured metabolites were decreased only in the white matter. This observation, combined with the DTI observed ADC increases and FA decrease, indicated a presence of vasogenic edema in the white matter.

  1. A dynamic model for power deposition in 3He lasers pumped by 3He(n,p) 3H reactions

    Science.gov (United States)

    Çetin, Füsun

    2004-07-01

    The coupled variation of power density with gas density in a nuclear-pumped laser, which is excited by 3He(n,p) 3H reaction products, is considered. In the literature, volumetric excitation by reaction products of 3He(n,p) 3H is only considered for the case in which gas density is uniform and does not change during the pumping. In this work, a time-dependent model describing the coupled fluid dynamic and particle transport behaviour of the gas has been developed. In modelling charge particle transport behaviour, a previously reported energy deposition model for a constant gas density is extended for a variable gas density by taking into account variations in the particle range, macroscopic cross sections and neutron flux depending on density field of the gas. The coupled equations, which are obtained by using the power deposition density expression obtained for variable gas density in the acoustically filtered equations of motion of the gas, are solved numerically. Spatial and temporal variations of power deposition density and gas density during the pumping pulse are determined for various operating pressures ranging from 0.5 to 10 atm. In the calculations, the characteristics of I.T.U TRIGA Mark-II Reactor are used and it is assumed that laser tube is placed in the centre of the reactor core. Obtained results are presented and examined.

  2. X-rays from antiprotonic3He and4He

    Science.gov (United States)

    Schneider, M.; Bacher, R.; Blüm, P.; Gotta, D.; Heitlinger, K.; Kunold, W.; Rohmann, D.; Egger, J.; Simons, L. M.; Elsener, K.

    1991-06-01

    Antiprotonic X-rays from the helium isotopes have been observed at pressures of 36, 72, 375 and 600 mbar. The antiproton beam from LEAR with momenta of 309 and 202 MeV/c has been stopped at these pressures using the cyclotron trap. The X-rays were detected with Si (Li) and intrinsic Ge semiconductor detectors. Absolute X-ray yields were determined and the strong-interaction 2p shifts and the 2p and 3d broadenings measured to be ɛ2p=(-17±4) eV, Γ2p=(25±9) eV and Γ3d=(2.14 ±0.18) meV for ¯p3He and ɛ2p=(-18±2) eV, Γ2p =(45±5) eV and Γ3d=(2.36±0.10) meV for ¯p4He.

  3. Fermion Monte Carlo Calculations on Liquid-3He

    Energy Technology Data Exchange (ETDEWEB)

    Kalos, M H; Colletti, L; Pederiva, F

    2004-03-16

    Methods and results for calculations of the ground state energy of the bulk system of {sup 3}He atoms are discussed. Results are encouraging: they believe that they demonstrate that their methods offer a solution of the ''fermion sign problem'' and the possibility of direct computation of many-fermion systems with no uncontrolled approximations. Nevertheless, the method is still rather inefficient compared with variational or fixed-node approximate methods. There appears to be a significant populations size effect. The situation is improved by the inclusion of ''Second Stage Importance Sampling'' and of ''Acceptance/Rejection'' adapted to their needs.

  4. Realization of administration unit for 3He with gas recycling

    International Nuclear Information System (INIS)

    Since many years hyperpolarized (HP) noble gases are used for MR-imaging of the lung. In the beginning the HP gas was filled in Tedlar-bags and directly inhaled by the patients. An administration unit was built respectively to the Medical Devices Law to administer patients HP noble gas boli (3He,129Xe) in defined quantities and at a predefined time during inspiration with high reproducibility and reliability without reducing MR-quality. The patient's airflows are monitored and recorded. It is possible to use gas admixtures, measure the polarization on line and collect the exhaled gas for later recycling. The first images with healthy volunteers were taken with this setup in a clinical study. Current results will be presented.

  5. Nuclear spin dynamics in solid 3He at ultralow temperatures

    International Nuclear Information System (INIS)

    In this thesis the experimental study of the spin dynamics of solid 3He is described. By means of magnetization measurements above 3 mK a Curie-Weiss behaviour was found with θW∼2.1 mK and by this an order parameter of J=θWkB/∼-0.5 KkB was observed, while in the range of 1 to 3 mK a pure Curie behaviour was found. By means of NMR measurements the values of τ1(6 mK)=240 ms±12 ms and τ1(1 mK)∼ 40 ms were determined, while spin-echo measurements yielded the spin-spin relaxation time τ2(6 mK)=4540 μs±140 μs. Furthermore neutron scattering studies were performed. (HSI)

  6. Vortex structure in rotational state superfluid 3He

    International Nuclear Information System (INIS)

    The structure of vortices in rotational superfluid 3He is considered. It is marked that in the A-phase quantum vortices are possible, in which the A-phase superfluid state is never disturbed. As a consequence of a discrete combined invariance (calibration transformation plus rotation of a spin subsystem) one more exotic type of vortices is possible in the A-phase. This is a hybrid of disclination in a magnetic anisotropy vector field d (with a half-integer Frank index) and vortex that possesses a half-integer number of circulation quanta. Such vortices can be observed at rotation of the A-phase confined between parallel plates. The vortex properties in the B-phase are determined by a continuous combined symmetry. The calculations show the vortex in the β-phase at low pressures to be in the ν-state. The vortices considered are observed in the NMR experiments

  7. Estimation of the extraterrestrial 3He and 20Ne fluxes on Earth from He and Ne systematics in marine sediments

    Science.gov (United States)

    Chavrit, Déborah; Moreira, Manuel; Moynier, Frédéric

    2016-04-01

    Sediments contain interplanetary dust particles (IDPs) carrying extraterrestrial noble gases, such as 3He, which have previously been used to estimate the IDP accretion flux over time and the duration of past environmental events. However, due to its high diffusivity, He can be lost by diffusion either due to frictional heating during entry in the atmosphere, or once it has been incorporated in the sediments. Therefore the absolute values of 3He IDP fluxes cannot be known. Due to its lower diffusivity, Ne is less likely to be lost by diffusion than He and can potentially provide an absolute IDP flux value. Here, we studied the Ne and He isotopic composition of 21 sediments of different ages (3 to 38 Myr, 56 Myr and 183 Myr) in order to better constrain the retention of 3He in such deposits. The samples are carbonates from 2 sites of the Integrated Ocean Drilling Program (IODP), which previously showed evidence of detectable extraterrestrial 3He, and from the Sancerre core in the Paris basin. The 3He/4He, 20Ne/22Ne and 21Ne/22Ne ratios of decarbonated residues vary respectively from 0.09×10-6 to 76.5×10-6, 9.54±0.08 to 11.30±0.60 and from 0.0295±0.0001 to 0.0344±0.0003. These isotopic compositions can be explained by a mixing between two terrestrial components (atmosphere and radiogenic He and nucleogenic Ne present in the terrigenous fractions) and an extraterrestrial component. The linear relationship between 20Ne/22Ne and 3He/22Ne ratios shows that the extraterrestrial component has a unique composition and is similar to the He and Ne composition of implanted solar wind. This composition is different from the individual stratospheric IDPs for which the Ne and He isotopic compositions have been measured. We suggest that this difference is due to a bias in the sampling of the individual IDPs previously analyzed toward the largest ones that are more likely to lose He during entry in the atmosphere. Our data further constrains the size of the majority of the

  8. Muon capture on the deuteron and 3He

    Directory of Open Access Journals (Sweden)

    Elmeshneb A. E.

    2014-01-01

    Full Text Available We plan to investigate the role of meson exchange currents in the description of the µ− + d → νµ + n + n and µ− + 3He → νµ + 3H reactions. They both are treated as the decay of the corresponding muonic atoms, with the muon initially on the lowest K shell. The muon binding energy in these atoms can be safely neglected and in the initial state we deal essentially with the deuteron (or 3He and muon at rest. These two reactions are interesting for several reasons. First of all, they offer a testing ground for the nuclear wave functions, which for any nucleon-nucleon (NN and three-nucleon (3N forces can be constructed for such light systems with great accuracy. In these reactions few-nucleon weak current operators are an important dynamical ingredient. In the current operators apart from the relatively well known single nucleon contributions, two-nucleon parts (generated by various meson exchanges play an important role. Their details are not well known and several models should be considered. We present our formalism for dealing with these reactions and a simple method for partial wave decomposition of the two-nucleon operators. The crucial nuclear matrix elements of the corresponding weak current operators will be calculated in the momentum space and using partial wave decomposition. The effect of meson exchanges will be investigated in the energy spectrum of the emitted neutrinos (in the deuteron case and in the total decay rates for the two reactions. We will employ various models of NN and 3N forces, such as the Bonn B or chiral NNLO potentials. Our results with the single nucleon currents look already very promising and we hope for the improvement in the description of the experimental data, when dominant two-nucleon current operators are included in our framework.

  9. Nuclear spin dynamics in solid {sup 3}He at ultralow temperatures; Kernspindynamik in festem {sup 3}He bei ultratiefen Temperaturen

    Energy Technology Data Exchange (ETDEWEB)

    Kath, Matthias

    2009-11-06

    In this thesis the experimental study of the spin dynamics of solid {sup 3}He is described. By means of magnetization measurements above 3 mK a Curie-Weiss behaviour was found with {theta}{sub W}{approx}2.1 mK and by this an order parameter of J={theta}{sub W}k{sub B}/{approx}-0.5 Kk{sub B} was observed, while in the range of 1 to 3 mK a pure Curie behaviour was found. By means of NMR measurements the values of {tau}{sub 1}(6 mK)=240 ms{+-}12 ms and {tau}{sub 1}(1 mK){approx} 40 ms were determined, while spin-echo measurements yielded the spin-spin relaxation time {tau}{sub 2}(6 mK)=4540 {mu}s{+-}140 {mu}s. Furthermore neutron scattering studies were performed. (HSI)

  10. Influence of lesion ratio on diagnostic performance of in-phase/opposed-phase imaging and apparent diffusion coefficient for differentiating acute benign vertebral fractures and metastases

    Institute of Scientific and Technical Information of China (English)

    LIN Fan; LEI Yi; LI Yang-bin

    2009-01-01

    Background The usefulness of in-phase/opposed-phase imaging and diffusion weighted imaging (DWI) in differentiating benign and neoplastic vertebral fractures has been described. In this study, we aimed to evaluate the influence of the severity of vertebral damage on the diagnostic performance of these two technologies.Methods Totally 59 patients with 68 acute benign vertebral fractures and 43 patients with 79 vertebral metastases were included in this study. The MR protocol included DWls and sagittal in-phase/opposed-phase gradient recalled sequence.The severity of vertebral damage was expressed by lesion ratio (LR, the ratio of lesion area to vertebral area on the slices of largest abnormal signal area in the T1-weighted sequence). Quantitative (signal intensity ratio (SIR) defined as signal intensity (SI) on opposed-phase gradient recalled echo (GRE) images divided by SI on in-phase; apparent diffusion coefficient (ADC) value derived from DWI analysis was performed, the relationships between LR and the measurements of these two technologies were analyzed using linear regression. The covariate-specific receiver operating characteristic (ROC) curves were also fitted to evaluate the influence of LR on the diagnostic performance of ADC and SIR. Results The difference in both SIR and ADC for vertebral metastasis and acute benign vertebral fractures was significant (P 0.05). More severe cases were associated with increased AUC for SIR.Conclusions LR is capable of affecting the diagnostic performances of chemical shift imaging. Thus, when applying these tests to make diagnoses on vertebral fractures, the severity of the vertebral damage should be taken into account.The covariate-specific ROC model is recommended because it substantially improves the ability to avoid bias when evaluating tests.

  11. Incorporating 3-D parent nuclide zonation for apatite 4He/3He thermochronometry: An example from the Appalachian Mountains

    Science.gov (United States)

    Fox, Matthew; McKeon, Ryan E.; Shuster, David L.

    2014-11-01

    ability to constrain km-scale exhumation with apatite 4He/3He thermochronometry is well established and the technique has been applied to a range of tectonic and geomorphic problems. However, multiple sources of uncertainty in specific crystal characteristics limit the applicability of the method, especially when geologic problems require identifying small perturbations in a cooling path. Here we present new 4He/3He thermochronometric data from the Appalachian Mountains, which indicate significant parent nuclide zonation in an apatite crystal. Using LA-ICPMS measurements of U and Th in the same crystal, we design a 3-D model of the crystal to explore the effects of intracrystal variability in radiation damage accumulation. We describe a numerical approach to solve the 3-D production-diffusion equation. Using our numerical model and a previously determined time temperature path for this part of the Appalachians, we find excellent agreement between predicted and observed 4He/3He spectra. Our results confirm this time-temperature path and highlight that for complex U and Th zonation patterns, 3-D numerical models are required to infer an accurate time-temperature history. In addition, our results provide independent and novel evidence for a radiation damage control on diffusivity. The ability to exploit intracrystal differences in 4He diffusivity [i.e., temperature sensitivity) greatly increases the potential to infer complex thermal histories.

  12. Correlation of Choline/Creatine and Apparent Diffusion Coefficient values with the prognostic parameters of Head and Neck Squamous Cell Carcinoma.

    Science.gov (United States)

    Razek, Ahmed Abdel Khalek Abdel; Nada, Nadia

    2016-04-01

    The aim of this study was to measure choline/creatine (Ch/Cr) levels through (1)H-MRS and apparent diffusion coefficient (ADC) values through diffusion-weighted MRI, and to correlate these values with the prognostic parameters of head and neck squamous cell carcinoma (HNSCC). The institutional review board approved this study and informed written consent was obtained from all study participants. A prospective study of 43 patients (31 men and 12 women; mean age, 65 years) with HNSCC was conducted. Single-voxel (1)H-MRS was performed at the tumor or metastatic cervical lymph node with point-resolved spectroscopy (PRESS) at TE = 135 ms. Diffusion-weighted MR images with b values of 0, 500 and 1000 s/mm(2) and contrast MRI of the head and neck were performed. The Ch/Cr levels and ADC values of HNSCC were calculated. The gross tumor volume (GTV) was also calculated. The degree of tumor differentiation was determined through pathological examination. The HNSCC Ch/Cr level was negatively correlated with the ADC value (r = -0.662, p = 0.001). There was a significant difference in the Ch/Cr and ADC values at different degrees of tumor differentiation (p = 0.003 and p = 0.001) and with different GTVs (p = 0.122 and p = 0.001). The following prognostic parameter categories were used: (i) poorly differentiated and undifferentiated versus well differentiated to moderately differentiated; and (ii) HNSCC with GTV 30 cm(3). The cut-off values for Cho/Cr and ADC for each category were 1.83, 0.95 and 1.94, 0.99, respectively, and the areas under the curve were 0.771, 0.967 and 0.726, 0.795, respectively, for each category. We conclude that the Ch/Cr levels determined using (1)H-MRS and the ADC values are well correlated with several prognostic parameters of HNSCC.

  13. Correlation between apparent diffusion coefficients and standardized uptake values in hybrid {sup 18}F-FDG PET/MR: Preliminary results in rectal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Ju Hye [Dept. of Nuclear Medicine, Kyungpook National University Hospital, Daegu (Korea, Republic of); Cho, Ihn Ho; Chun, Kyung Ah; Kong, Eun Jung; Kwon, Sang Don; Kim, Jae Hwang [Yeungnam University Hospital, Daegu (Korea, Republic of)

    2016-06-15

    Fluorine-18-fluorodeoxyglucose ({sup 18}F-FDG) positron emission tomography (PET) and diffusion-weighted magnetic resonance imaging (DWI) share the same role in clinical oncology and it is feasible to obtain the standardized uptake value (SUV) and apparent diffusion coefficient (ADC) simultaneously by emerging the hybrid positron emission tomography/magnetic resonance (PET/MR). This study investigated the correlation between the ADCs of rectal cancer lesions and their SUVs derived from hybrid PET/MR. Nine patients with histologically proven rectal adenocarcinoma (5 men, 4 women; mean age, 70 ± 15.91 years) underwent torso {sup 18}F-FDG PET/CT and regional hybrid {sup 18}F-FDG PET/MR sequentially. A fixed threshold value of 40 % of maximum uptake was used to determine tumor volume of interest (VOI) on PET image; SUV{sub max}, SUV{sub peak}, and SUV{sub mean} were calculated automatically. A single freehand region of interest (ROI) was drawn on high b-value (b1000) DWI image and copied to corresponding ADC map to determine the ADCmean of rectal cancer lesion. Spearman'rank correlation coefficient (ρ) was calculated to determine the correlation between SUVs and ADC values. SUV{sub max}, SUV{sub peak}, and SUV{sub mean} derived by hybrid PET/MR were 12.35 ± 4.66 (mean ± standard deviation), 9.66  ± 3.15 and 7.41 ± 2.54, respectively. The ADCmean value of rectal cancer lesions was 1.02 ± 0.08 × 10{sup -3}mm{sup 2}/s. ADCmean was significantly and inversely correlated with SUV values (SUV{sub max}, ρ = -0.95, p < 0.001; SUV{sub peak}, ρ = -0.93, p < 0.001; SUV{sub mean}, ρ = -0.91, p = 0.001). This preliminary hybrid PET/MR study demonstrates a significant inverse correlation exists between metabolic activity on {sup 18}F-FDG PET and water diffusion on DWI in rectal cancer.

  14. NMR studies on vortices in rotating 3He-A

    International Nuclear Information System (INIS)

    NMR measurements are reported on rotating 3He-A in a long cylindrical geometry of 5 mm diameter at a liquid pressure of 29.3 bar and in axial magnetic fields of 14.2, 28.4, and 56.9 mT. At 28.4 mT, NMR studies are also reported in fields inclined by 250 and 900 from the axis of rotation. The frequency shift, the width, and the intensity of the spin wavemodes localized on the soft vortex cores, as well as the additional broadening of the main NMR line during rotation, were measured as a function of temperature, angular velocity Ω, magnetic field intensity, and its inclination angle. Also observed were a critical angular velocity of vortex formation, hysteretic behavior in the number of vortices when comparing accelerating rotation to decelerating, and metastable vortex densities, presumably a vortex tangle after rapid oscillatory acceleration. The results can be understood in terms of the continuous 4π vortices first proposed by Seppaelae and Volovik

  15. Vortex sheet in superfluid 3He-A

    International Nuclear Information System (INIS)

    A new state of rotating superfluid 3He-A has been found recently. Usually superfluids respond to rotation by creating an array of vortex lines, which are parallel to the rotation axis, and the circulation around them is quantized. In the new state the vorticity is located on a 2 dimensional sheet instead of 1 D lines. The sheet is parallel to the rotation axis z but in the x - y plane it folds to equidistant layers. The distance between the layers is larger but on the same order of magnitude as the distance between vortex lines. In contrast to other superfluids, the sheet is stable in the A phase because, of its internal structure. The sheet has as a backbone a topologically stable domain wall called soliton, to which non-singular vorticity is bound. Thus it can exist in spite of its presumably higher energy. The vortex sheet is distinguished by its NMR response, in particular because of its higher absorption at a characteristic frequency. Experiment and theory on the vortex sheet are in good agreement

  16. The Diagnostic Ability of Follow-Up Imaging Biomarkers after Treatment of Glioblastoma in the Temozolomide Era: Implications from Proton MR Spectroscopy and Apparent Diffusion Coefficient Mapping

    Directory of Open Access Journals (Sweden)

    Martin Bulik

    2015-01-01

    Full Text Available Objective. To prospectively determine institutional cut-off values of apparent diffusion coefficients (ADCs and concentration of tissue metabolites measured by MR spectroscopy (MRS for early differentiation between glioblastoma (GBM relapse and treatment-related changes after standard treatment. Materials and Methods. Twenty-four GBM patients who received gross total resection and standard adjuvant therapy underwent MRI examination focusing on the enhancing region suspected of tumor recurrence. ADC maps, concentrations of N-acetylaspartate, choline, creatine, lipids, and lactate, and metabolite ratios were determined. Final diagnosis as determined by biopsy or follow-up imaging was correlated to the results of advanced MRI findings. Results. Eighteen (75% and 6 (25% patients developed tumor recurrence and pseudoprogression, respectively. Mean time to radiographic progression from the end of chemoradiotherapy was 5.8 ± 5.6 months. Significant differences in ADC and MRS data were observed between those with progression and pseudoprogression. Recurrence was characterized by N-acetylaspartate ≤ 1.5 mM, choline/N-acetylaspartate ≥ 1.4 (sensitivity 100%, specificity 91.7%, N-acetylaspartate/creatine ≤ 0.7, and ADC ≤ 1300 × 10−6 mm2/s (sensitivity 100%, specificity 100%. Conclusion. Institutional validation of cut-off values obtained from advanced MRI methods is warranted not only for diagnosis of GBM recurrence, but also as enrollment criteria in salvage clinical trials and for reporting of outcomes of initial treatment.

  17. A spatiotemporal theory for MRI T2 relaxation time and apparent diffusion coefficient in the brain during acute ischaemia: Application and validation in a rat acute stroke model.

    Science.gov (United States)

    Knight, Michael J; McGarry, Bryony L; Rogers, Harriet J; Jokivarsi, Kimmo T; Gröhn, Olli Hj; Kauppinen, Risto A

    2016-07-01

    The objective of this study is to present a mathematical model which can describe the spatiotemporal progression of cerebral ischaemia and predict magnetic resonance observables including the apparent diffusion coefficient (ADC) of water and transverse relaxation time T2 This is motivated by the sensitivity of the ADC to the location of cerebral ischaemia and T2 to its time-course, and that it has thus far proven challenging to relate observations of changes in these MR parameters to stroke timing, which is of considerable importance in making treatment choices in clinics. Our mathematical model, called the cytotoxic oedema/dissociation (CED) model, is based on the transit of water from the extra- to the intra-cellular environment (cytotoxic oedema) and concomitant degradation of supramacromolecular and macromolecular structures (such as microtubules and the cytoskeleton). It explains experimental observations of ADC and T2, as well as identifying the rate of spread of effects of ischaemia through a tissue as a dominant system parameter. The model brings the direct extraction of the timing of ischaemic stroke from quantitative MRI closer to reality, as well as providing insight on ischaemia pathology by imaging in general. We anticipate that this may improve patient access to thrombolytic treatment as a future application. PMID:26661188

  18. The apparent diffusion coefficient of a primary lesion correlates with local failure of head and neck squamous cell carcinoma treated with radiotherapy. President award proceedings

    International Nuclear Information System (INIS)

    We prospectively investigated whether the value of the apparent diffusion coefficient (ADC) of a primary lesion prior to treatment correlated with local failure of head and neck squamous cell carcinoma (HNSCC) following radiotherapy. In 17 patients who underwent radiotherapy for primary HNSCC, we compared variables considered to affect local failure, including parameters related to magnetic resonance (MR) imaging, such as ADC and its alteration ratio, between cases of local failure and controls and analyzed survival among those patients in whom the variables differed or demonstrated association with local failure. We also retrospectively analyzed variables in a validation study of 40 patients. In the prospective study, pretreatment values of ADChigh (calculated with b-values of 300, 500, 750, and 1000 s/mm2) alone showed significant association with local failure (P=0.0186). In the validation study, pretreatment values of tumor volume (P=0.0217) and ADChigh (P=0.0001) were significantly associated with local failure. Pretreatment ADChigh was superior to pretreatment tumor volume regarding association with local failure. These results suggest that pretreatment values of both ADC obtained using high b-values and tumor volume correlate with local failure of HNSCC treated with radiotherapy. (author)

  19. Transfer Excitation Processes Observed in N3+-He and O3+-He Collisions at Elab = 33 eV

    Science.gov (United States)

    Itoh, Yoh

    2016-09-01

    We measured the relative state-selective differential cross sections (DCSs) for one-electron capture reactions using a crossed-beam apparatus. The scattering angle θlab studied in the laboratory frame ranged from -3.0 to 22° and the laboratory collision energy Elab was 33 eV. Only the transfer excitation processes, i.e., the electron capture reactions with the simultaneous excitation of the projectile, were observed. The DCSs were determined for the following reactions: N3+ (1s2 2s2 1S) + He (1s2 1S) → N2+ (1s2 2s2p2 2D) + He+ (1s 2S) + 10.3 eV, O3+ (1s2 2s2 2p 2P) + He (1s2 1S) → O2+ (1s2 2s 2p3 3P) + He+ (1s 2S) + 12.7 eV, and O3+ (1s2 2s2 2p 2P) + He (1s2 1S) → O2+ (1s2 2s 2p3 3D) + He+ (1s 2S) + 15.5 eV. In the N3+-He system, the DCSs for the reaction are zero at the center-of-mass angle θcm = 0 and show a peak at a certain angle and a shoulder at a larger angle. In the O3+-He system, the DCSs are again zero at θcm = 0. The capture process to the O2+ (1s2 2s 2p3 3P) state is mainly observed at smaller scattering angles, and the reaction to the O2+ (1s2 2s 2p3 3D) state becomes dominant with increasing scattering angle. A classical trajectory analysis within the two-state approximation based on the ab initio potentials for (NHe)3+ revealed that the transfer excitation of a two-electron process takes place through a single crossing of the relevant potentials.

  20. Economic evaluation of D-T, D-3He, and catalyzed D-D fusion reactors

    International Nuclear Information System (INIS)

    Because the D-3He reaction generates no neutrons and the D-D reaction can use abundant fuel resources, these reactions are expected to be used in advanced fuel fusion reactors. Economic considerations and engineering problems are important for realizing such reactors as commercial plants. Therefore, we estimate and compare the cost of electricity (COE) from D-T, D-3He, and catalyzed D-D (cat D-D) fusion reactors. D-3He and cat D-D reactors have a low neutron wall load. Therefore, the D-3He reactor has no wall replacement cost. In addition, no tritium breeding system is needed for the D-3He reactor, but 3He gas is rare. Because the reaction rates of the D-3He and D-D reactions are less, D-3He and D-D reactors require highly efficient confinement properties and operation at high ion temperatures. Furthermore, the power densities of D-3He and D-D reactors are smaller than that of the D-T reactor; thus, D-3He and D-D reactors require a large plasma volume. Assuming a high ion temperature (= 60 keV) and high normalized beta (= 7-8), the COE of a D-3He reactor is expected to be similar to that of a D-T reactor. In terms of cost, cat D-D is disadvantageous in comparison with D-3He and D-T reactors. (author)

  1. Chlorofluorocarbons and ~3H/~3He in groundwater——Applications in tracing and dating young groundwater

    Institute of Scientific and Technical Information of China (English)

    秦大军; 王浩

    2001-01-01

    Based on the CFC concentration, the fraction of young groundwater in a mixture with old groundwater can be defined if the age of the young component is known. The authors argued that the ratio of [3HeJ/[3Ht] in a young water is independent of its mixing with old waters. Hence, the 3H-3He can be used to determine age of the young groundwater, though mixing with old ground-water may occur. CFC concentrations are susceptible to change by mixing of young and old water. The combination of CFCs and tritium/helium can provide confidential apparent age of the young groundwater and fraction of the young water in the mixture with old groundwater.

  2. Assessment of diffusional anisotropy of the corpus callosum in patients with multiple lacunar infarcts. Relationship between the apparent diffusion coefficient ratio and global cognitive impairment

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, Makiko; Hayashi, Hiromitsu; Amano, Yasuo; Takagi, Ryo; Nakahara, Madoka; Kumazaki, Tatsuo [Nippon Medical School, Tokyo (Japan); Cho, Keiichi; Okada, Susumu

    1998-06-01

    The purpose of the present study is to evaluate diffusional anisotropy of white matter in patients with multiple lacunar infarcts using diffusion-weighted echo-planar imaging (DW-EPI), and to examine the relationship between diffusional anisotropy and global cognitive ability as assessed by the mini-mental status examination (MMSE). In particular, we focused on the parameter changes for the corpus callosum as a marker for disconnection of the associative cortices. Twenty-nine patients divided into 2 cognitive level groups (low MMSE, n=16; high MMSE, n=13) and 8 normal controls were examined with a GE 1.5 T Horizon system. Three series of DW-EPI images were obtained using the following epidw{sub g}{center_dot}psd{sup TM} sequence: TR/TE=6500/120 ms, single shot, 6.5 mm slice thickness and 1.5 mm gap transaxial sections of the whole brain, with b-factors of 0 and 710 along each x- and y-axial direction. The parametric maps for apparent diffusion coefficient (ADC) in each direction, ADC(x) and ADC(y), and their rate map (ADC rate=ADC(x)/ADC(y)) were created on a pixel-by-pixel basis. ROI data were extracted from images of the corpus callosum and bilateral optic radiata. As a result, the ADC(x) was markedly larger for corpus callosum than that for optic radiata, whereas the ADC(y) showed an inverse trend, attributable to regional differences of diffusional anisotropy. In corpus callosum, however, the ADC(y) values were observed to increase with the level of disease severity, resulting in a decrease of the ADC rate. Notably, there was a significant difference between the three groups for callosal genu, with a slight positive correlation between the ADC rate and the MMSE scores. Our study suggests that a relationship exists between the reduction of diffusional anisotropy in callosal genu and the global cognitive impairment seen in patients with multiple lacunar infarcts. (K.H.)

  3. K− 3He and K− 4He interactions at low energies

    Directory of Open Access Journals (Sweden)

    Grishina V.Yu.

    2010-04-01

    Full Text Available Using the multiple scattering approach (MSA in the fixed center approximation we calculated the K− 4He and K− 3He scattering lengths. The K− 4He scattering length is also analyzed in the optical potential model. Within the MSA the K− 3He final state interaction factor was also calculated. It is found that the K− 3He mass spectrum for the pd → 3HeK+ K− reaction is expected to be influenced by the K− 3He FSI effect.

  4. Investigation of adsorption and wetting of 3He on cesium and cesiated glass

    International Nuclear Information System (INIS)

    Experiments have been carried out to investigate the binding of 3He on cesium substrates, using optical pumping to spin-polarize the atoms. The behavior of 3He on the walls at low temperature can be analyzed through the evolution of the nuclear magnetization of the sample. Preliminary results are presented, including: (1) adsorption studies of gaseous 3He on cesiated glass; (2) magnetic relaxation time of polarized liquid 3He on cesium and cesiated glass; (3) evidence for wetting of liquid 3He on cesium. 8 refs., 2 figs

  5. Simultaneous [18F]FDG-PET/MRI: Correlation of Apparent Diffusion Coefficient (ADC and Standardized Uptake Value (SUV in Primary and Recurrent Cervical Cancer.

    Directory of Open Access Journals (Sweden)

    P Brandmaier

    Full Text Available Previous non-simultaneous PET/MR studies have shown heterogeneous results about the correlation between standardized uptake values (SUVs and apparent diffusion coefficients (ADCs. The aim of this study was to investigate correlations in patients with primary and recurrent tumors using a simultaneous PET/MRI system which could lead to a better understanding of tumor biology and might play a role in early response assessment.We included 31 patients with histologically confirmed primary (n = 14 or recurrent cervical cancer (n = 17 who underwent simultaneous whole-body 18F-FDG-PET/MRI comprising DWI. Image analysis was performed by a radiologist and a nuclear physician who identified tumor margins and quantified ADC and SUV. Pearson correlations were calculated to investigate the association between ADC and SUV.92 lesions were detected. We found a significant inverse correlation between SUVmax and ADCmin (r = -0.532, p = 0.05 in primary tumors as well as in primary metastases (r = -0.362, p = 0.05 and between SUVmean and ADCmin (r = -0.403, p = 0.03. In recurrent local tumors we found correlations for SUVmax and ADCmin (r = -0.747, p = 0.002 and SUVmean and ADCmin (r = -0.773, p = 0.001. Associations for recurrent metastases were not significant (p>0.05.Our study demonstrates the feasibility of fast and reliable measurement of SUV and ADC with simultaneous PET/MRI. In patients with cervical cancer we found significant inverse correlations for SUV and ADC which could play a major role for further tumor characterization and therapy decisions.

  6. OBSERVATIONS OF SOLAR ENERGETIC PARTICLES FROM {sup 3}He-RICH EVENTS OVER A WIDE RANGE OF HELIOGRAPHIC LONGITUDE

    Energy Technology Data Exchange (ETDEWEB)

    Wiedenbeck, M. E. [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Mason, G. M.; Haggerty, D. K [Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723 (United States); Cohen, C. M. S. [Space Radiation Laboratory, California Institute of Technology, Pasadena, CA 91125 (United States); Nitta, N. V. [Lockheed-Martin Solar and Astrophysics Lab, Palo Alto, CA 94304 (United States); Gomez-Herrero, R., E-mail: mark.e.wiedenbeck@jpl.nasa.gov [Christian-Albrechts Universitaet zu Kiel, D-24118 Kiel (Germany)

    2013-01-01

    A prevailing model for the origin of {sup 3}He-rich solar energetic particle (SEP) events attributes particle acceleration to processes associated with the reconnection between closed magnetic field lines in an active region and neighboring open field lines. The open field from the small reconnection volume then provides a path along which accelerated particles escape into a relatively narrow range of angles in the heliosphere. The narrow width (standard deviation <20 Degree-Sign ) of the distribution of X-ray flare longitudes found to be associated with {sup 3}He-rich SEP events detected at a single spacecraft at 1 AU supports this model. We report multispacecraft observations of individual {sup 3}He-rich SEP events that occurred during the solar minimum time period from 2007 January through 2011 January using instrumentation carried by the two Solar Terrestrial Relations Observatory spacecraft and the Advanced Composition Explorer. We find that detections of {sup 3}He-rich events at pairs of spacecraft are not uncommon, even when their longitudinal separation is >60 Degree-Sign . We present the observations of the {sup 3}He-rich event of 2010 February 7, which was detected at all three spacecraft when they spanned 136 Degree-Sign in heliographic longitude. Measured fluences of {sup 3}He in this event were found to have a strong dependence on longitude which is well fit by a Gaussian with standard deviation {approx}48 Degree-Sign centered at the longitude that is connected to the source region by a nominal Parker spiral magnetic field. We discuss several mechanisms for distributing flare-accelerated particles over a wide range of heliographic longitudes including interplanetary diffusion perpendicular to the magnetic field, spreading of a compact cluster of open field lines between the active region and the source surface where the field becomes radial and opens out into the heliosphere, and distortion of the interplanetary field by a preceding coronal mass

  7. WE-G-18C-02: Estimation of Optimal B-Value Set for Obtaining Apparent Diffusion Coefficient Free From Perfusion in Non-Small Cell Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Karki, K; Hugo, G; Ford, J; Saraiya, S; Weiss, E [Radiation Oncology, Virginia Commonwealth University, Richmond, VA (United States); Olsen, K; Groves, R [Radiology, Virginia Commonwealth University, Richmond, VA (United States)

    2014-06-15

    Purpose: Diffusion-weighted MRI (DW-MRI) is increasingly being investigated for radiotherapy planning and response assessment. Selection of a limited number of b-values in DW-MRI is important to keep geometrical variations low and imaging time short. We investigated various b-value sets to determine an optimal set for obtaining monoexponential apparent diffusion coefficient (ADC) close to perfusion-insensitive intravoxel incoherent motion (IVIM) model ADC (ADCIVIM) in nonsmall cell lung cancer. Methods: Seven patients had 27 DW-MRI scans before and during radiotherapy in a 1.5T scanner. Respiratory triggering was applied to the echo-planar DW-MRI with TR=4500ms approximately, TE=74ms, pixel size=1.98X1.98mm{sub 2}, slice thickness=4–6mm and 7 axial slices. Diffusion gradients were applied to all three axes producing traceweighted images with eight b-values of 0–1000μs/μm{sup 2}. Monoexponential model ADC values using various b-value sets were compared to ADCIVIM using all b-values. To compare the relative noise in ADC maps, intra-scan coefficient of variation (CV) of active tumor volumes was computed. Results: ADCIVIM, perfusion coefficient and perfusion fraction for tumor volumes were in the range of 880-1622 μm{sup 2}/s, 8119-33834 μm{sup 2}/s and 0.104–0.349, respectively. ADC values using sets of 250, 800 and 1000; 250, 650 and 1000; and 250–1000μs/μm{sup 2} only were not significantly different from ADCIVIM(p>0.05, paired t-test). Error in ADC values for 0–1000, 50–1000, 100–1000, 250–1000, 500–1000, and three b-value sets- 250, 500 and 1000; 250, 650 and 1000; and 250, 800 and 1000μs/μm{sup 2} were 15.0, 9.4, 5.6, 1.4, 11.7, 3.7, 2.0 and 0.2% relative to the reference-standard ADCIVIM, respectively. Mean intrascan CV was 20.2, 20.9, 21.9, 24.9, 32.6, 25.8, 25.4 and 24.8%, respectively, whereas that for ADCIVIM was 23.3%. Conclusion: ADC values of two 3 b-value sets

  8. 3He lung morphometry technique: Accuracy analysis and pulse sequence optimization

    Science.gov (United States)

    Sukstanskii, A. L.; Conradi, M. S.; Yablonskiy, D. A.

    2010-12-01

    The 3He lung morphometry technique (Yablonskiy et al., JAP, 2009), based on MRI measurements of hyperpolarized gas diffusion in lung airspaces, provides unique information on the lung microstructure at the alveolar level. 3D tomographic images of standard morphological parameters (mean airspace chord length, lung parenchyma surface-to-volume ratio, and the number of alveoli per unit lung volume) can be created from a rather short (several seconds) MRI scan. These parameters are most commonly used to characterize lung morphometry but were not previously available from in vivo studies. A background of the 3He lung morphometry technique is based on a previously proposed model of lung acinar airways, treated as cylindrical passages of external radius R covered by alveolar sleeves of depth h, and on a theory of gas diffusion in these airways. The initial works approximated the acinar airways as very long cylinders, all with the same R and h. The present work aims at analyzing effects of realistic acinar airway structures, incorporating airway branching, physiological airway lengths, a physiological ratio of airway ducts and sacs, and distributions of R and h. By means of Monte-Carlo computer simulations, we demonstrate that our technique allows rather accurate measurements of geometrical and morphological parameters of acinar airways. In particular, the accuracy of determining one of the most important physiological parameter of lung parenchyma - surface-to-volume ratio - does not exceed several percent. Second, we analyze the effect of the susceptibility induced inhomogeneous magnetic field on the parameter estimate and demonstrate that this effect is rather negligible at B0 ⩽ 3T and becomes substantial only at higher B0 Third, we theoretically derive an optimal choice of MR pulse sequence parameters, which should be used to acquire a series of diffusion-attenuated MR signals, allowing a substantial decrease in the acquisition time and improvement in accuracy of the

  9. Experimental study of fusion neutron and proton yields produced by petawatt-laser-irradiated D2-3He or CD4-3He clustering gases

    CERN Document Server

    Bang, W; Bonasera, A; Quevedo, H J; Dyer, G; Bernstein, A C; Hagel, K; Schmidt, K; Gaul, E; Donovan, M E; Consoli, F; De Angelis, R; Andreoli, P; Barbarino, M; Kimura, S; Mazzocco, M; Natowitz, J B; Ditmire, T

    2013-01-01

    We report on experiments in which the Texas Petawatt laser irradiated a mixture of deuterium or deuterated methane clusters and helium-3 gas, generating three types of nuclear fusion reactions: D(d, 3He)n, D(d, t)p and 3He(d, p)4He. We measured the yields of fusion neutrons and protons from these reactions and found them to agree with yields based on a simple cylindrical plasma model using known cross sections and measured plasma parameters. Within our measurement errors, the fusion products were isotropically distributed. Plasma temperatures, important for the cross sections, were determined by two independent methods: (1) deuterium ion time-of-flight, and (2) utilizing the ratio of neutron yield to proton yield from D(d, 3He)n and 3He(d, p)4He reactions, respectively. This experiment produced the highest ion temperature ever achieved with laser-irradiated deuterium clusters.

  10. Interferometric and acoustic measurements in superfluid (3)He-B and wetting studies in (3)He/(4)He mixtures. Doctoral thesis

    Energy Technology Data Exchange (ETDEWEB)

    Alles, H.

    1995-06-22

    In this thesis work superfluid (3)He was investigated by two methods. First, ultrasonic experiments on (3)He-B were carried out using two coincident zero sound pulses. The second technique is optics, a novel method for ultra low temperatures. The developed method, two-beam interferometry, was employed successfully for studies of wetting phenomena in liquid (3)He/(4)He mixtures as well. This publication contains the results of a acoustic spectroscopy on (3)He-B. Most importantly, the real squashing collective mode (rsq) was excited by two simultaneous sound pulses yielding two phonon absorption (TPA). This nonlinear phenomenon was applied to study the dispersion relation of the rsq-mode. Zeeman splitting of the nonlinearly excited rsq-mode was investigated in a magnetic field. By means of TPA, an anomalous behavior was found also near the pair-breaking edge.

  11. Estimation of optimal b-value sets for obtaining apparent diffusion coefficient free from perfusion in non-small cell lung cancer

    Science.gov (United States)

    Karki, Kishor; Hugo, Geoffrey D.; Ford, John C.; Olsen, Kathryn M.; Saraiya, Siddharth; Groves, Robert; Weiss, Elisabeth

    2015-10-01

    The purpose of this study was to determine optimal sets of b-values in diffusion-weighted MRI (DW-MRI) for obtaining monoexponential apparent diffusion coefficient (ADC) close to perfusion-insensitive intravoxel incoherent motion (IVIM) model ADC (ADCIVIM) in non-small cell lung cancer. Ten subjects had 40 DW-MRI scans before and during radiotherapy in a 1.5 T MRI scanner. Respiratory triggering was applied to the echo-planar DW-MRI with \\text{TR}≈ 4500 ms, TE  =  74 ms, eight b-values of 0-1000 μs μm-2, pixel size  =  1.98× 1.98 mm2, slice thickness  =  6 mm, interslice gap  =  1.2 mm, 7 axial slices and total acquisition time ≈6 min. One or more DW-MRI scans together covered the whole tumour volume. Monoexponential model ADC values using various b-value sets were compared to reference-standard ADCIVIM values using all eight b-values. Intra-scan coefficient of variation (CV) of active tumour volumes was computed to compare the relative noise in ADC maps. ADC values for one pre-treatment DW-MRI scan of each of the 10 subjects were computed using b-value pairs from DW-MRI images synthesized for b-values of 0-2000 μs μm-2 from the estimated IVIM parametric maps and corrupted by various Rician noise levels. The square root of mean of squared error percentage (RMSE) of the ADC value relative to the corresponding ADCIVIM for the tumour volume of the scan was computed. Monoexponential ADC values for the b-value sets of 250 and 1000; 250, 500 and 1000; 250, 650 and 1000; 250, 800 and 1000; and 250-1000 μs μm-2 were not significantly different from ADCIVIM values (p>0.05 , paired t-test). Mean error in ADC values for these sets relative to ADCIVIM were within 3.5%. Intra-scan CVs for these sets were comparable to that for ADCIVIM. The monoexponential ADC values for other sets—0-1000 50-1000 100-1000 500-1000 and 250 and 800 μs μm-2 were significantly different from the ADCIVIM values. From Rician noise simulation

  12. Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas

    Energy Technology Data Exchange (ETDEWEB)

    Server, Andres, E-mail: a.s.alonso@medisin.uio.no [Section of Neuroradiology, Department of Radiology and Nuclear Medicine, Oslo University Hospital-Ullevaal and University of Oslo, Kirkeveien 166, NO-0407 Oslo (Norway); Kulle, Bettina, E-mail: b.k.andreassen@medisin.uio.no [Department of Biostatistics, University of Oslo, Oslo (Norway); Gadmar, Oystein B., E-mail: gays@uus.no [Interventional Centre, Oslo University Hospital and Institute for Hospital Medicine, University of Oslo, Oslo (Norway); Josefsen, Roger, E-mail: roos@uus.no [Department of Neurosurgery, Oslo University Hospital-Ullevaal, Oslo (Norway); Kumar, Theresa, E-mail: thku@uus.no [Department of Pathology, Oslo University Hospital-Ullevaal, Oslo (Norway); Nakstad, Per H., E-mail: pena@uus.no [Section of Neuroradiology, Department of Radiology and Nuclear Medicine, Oslo University Hospital-Ullevaal and University of Oslo, Kirkeveien 166, NO-0407 Oslo (Norway)

    2011-11-15

    Purpose: Tumor grading is very important both in treatment decision and evaluation of prognosis. While tissue samples are obtained as part of most therapeutic approaches, factors that may result in inaccurate grading due to sampling error (namely, heterogeneity in tissue sampling, as well as tumor-grade heterogeneity within the same tumor specimen), have led to a desire to use imaging better to ascertain tumor grade. The purpose in our study was to evaluate the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), area under the curve (AUC), and accuracy of diffusion-weighted MR imaging (DWI), proton MR spectroscopic imaging (MRSI) or both in grading primary cerebral gliomas. Materials and methods: We performed conventional MR imaging (MR), DWI, and MRSI in 74 patients with newly diagnosed brain gliomas: 59 patients had histologically verified high-grade gliomas: 37 glioblastomas multiform (GBM) and 22 anaplastic astrocytomas (AA), and 15 patients had low-grade gliomas. Apparent diffusion coefficient (ADC) values of tumor and peritumoral edema, and ADC ratios (ADC in tumor or peritumoral edema to ADC of contralateral white matter, as well as ADC in tumor to ADC in peritumoral edema) were determined from three regions of interest. The average of the mean, maximum, and minimum for ADC variables was calculated for each patient. The metabolite ratios of Cho/Cr and Cho/NAA at intermediate TE were assessed from spectral maps in the solid portion of tumor, peritumoral edema and contralateral normal-appearing white matter. Tumor grade determined with the two methods was then compared with that from histopathologic grading. Logistic regression and receiver operating characteristic (ROC) curve analysis were performed to determine optimum thresholds for tumor grading. Measures of diagnostic examination performance, such as sensitivity, specificity, PPV, NPV, AUC, and accuracy for identifying high-grade gliomas were also calculated

  13. Near threshold two meson production with the pd→3Heπ+π- and pd→3HeK+K- reactions

    Science.gov (United States)

    Bellemann, F.; Berg, A.; Bisplinghoff, J.; Bohlscheid, G.; Ernst, J.; Henrich, C.; Hinterberger, F.; Ibald, R.; Jahn, R.; Jarczyk, L.; Joosten, R.; Kozela, A.; Machner, H.; Magiera, A.; Maschuw, R.; Mayer-Kuckuk, T.; Mertler, G.; Munkel, J.; von Neumann-Cosel, P.; Rosendaal, D.; von Rossen, P.; Schnitker, H.; Scho, K.; Smyrski, J.; Strzalkowski, A.; Tölle, R.; Wilkin, C.

    2000-06-01

    Near threshold two meson production via the reactions pd→3Heπ+π- and pd→3HeK+K- was measured kinematically complete with the MOMO experiment at COSY. The obtained two pion invariant mass spectra and angular distributions depict a remarkable deviation from phase space. The two kaon data are consistent with phase space topped by a clear signal of the φ meson.

  14. Energy dependence of the 6Li(π+,3He)3He reaction at 60, 75 and 90 MeV

    International Nuclear Information System (INIS)

    Differential cross sections for the pionic fission reaction 6Li(π+,3He)3He at T sub(π) = 60, 75 and 90 MeV have been measured for theta sub(c.m.) = 4l degrees. The energy dependence of the differential cross section is found to follow an exponential decrease with increasing incident pion energy and is compared with existing theoretical predictions

  15. A 3He Cryostat for Scientific Measurements in Pulsed High Magnetic Fields

    Science.gov (United States)

    Wang, Shaoliang; Li, Liang; Liu, Mengyu; Zuo, Huakun; Peng, Tao

    A top loading 3He cryostat has been developed for scientific experiments with a 60 T pulsed magnetic field facility at Wuhan National High Magnetic Field Center. The cryostat consists of a 4He bath cryostat, a 3He insert and a closed circulation system for 3He gas handling. To eliminate the eddy current heating during the pulse, the tail of the 3He insert with a vacuum space at the bottom is made from fiberglass tubing coated with epoxy. The 3He bath is separated from the 4He bath with the vacuum space. The 4He bath cryostat provides cooling power to condense 3He gas by a neck tube on top of the tail. Experimental results have shown that the sample can be cooled down to 385 mK and kept cold for more than 150 second by one-shot cooling, which is sufficiently long for an experiment in a pulsed high magnetic field.

  16. Observation of Majorana Quasiparticles Surface States in Superfluid ${^3}$He-B by Heat Capacity Measurements

    OpenAIRE

    Bunkov, Yury M.; Gazizulin, Rasul R.

    2016-01-01

    We report about direct measurements of heat capacity of Majorana quasiparticles in superfluid ${^3}$He-B which appear near the surface of the experimental bolometer on the coherence length ${\\xi}$. Two bolometers with different surface-to-volume ratios were used which allows us to have different calibrated contributions from Majorana quasiparticles to the ${^3}$He heat capacity. Estimations of possible impact of ${^3}$He layers adsorbed on the walls of the bolometer have been done.

  17. Development of polarized {sup 3}He filter for polarized neutron experiment

    Energy Technology Data Exchange (ETDEWEB)

    Sakai, K.; Sato, H.; Yoshimi, A.; Asahi, K. [Tokyo Inst. of Tech. (Japan). Faculty of Science; Masuda, Y.; Muto, S.; Ishimoto, S.; Morimoto, K.

    1996-08-01

    A high-pressure polarized {sup 3}He gas cell, pumped with two diode lasers, has been developed at KEK for use as a polarizer and a spin analyzer for low energy neutrons. The polarization attained of {sup 3}He was determined through the measurement of the transmission of the unpolarized neutrons through the {sup 3}He cell. So far we obtained P{sub He}=18% at 10 atm and P{sub He}=12% at 20 atm. (author)

  18. {sup 3}He-MRI in follow-up of lung transplant recipients

    Energy Technology Data Exchange (ETDEWEB)

    Gast, Klaus Kurt; Zaporozhan, Julia; Ley, Sebastian; Biedermann, Alexander; Knitz, Frank; Eberle, Balthasar; Schmiedeskamp, Joerg; Heussel, Claus-Peter; Mayer, Eckhard; Schreiber, Wolfgang Guenter; Thelen, Manfred; Kauczor, Hans-Ulrich [Department of Radiology, Johannes Gutenberg University Hospital, Langenbeckstrasse 1, 55131, Mainz (Germany)

    2004-01-01

    The aim of this study was to evaluate the possible contribution of {sup 3}He-MRI to detect obliterative bronchiolitis (OB) in the follow-up of lung transplant recipients. Nine single- and double-lung transplanted patients were studied by an initial and a follow-up {sup 3}He-MRI study. Images were evaluated subjectively by estimation of ventilation defect area and quantitatively by individually adapted threshold segmentation and subsequent calculation of ventilated lung volume. Bronchiolitis obliterans syndrome (BOS) was diagnosed using pulmonary function tests. At {sup 3}He-MRI, OB was suspected if ventilated lung volume had decreased by 10% or more at the follow-up MRI study compared with the initial study. General accordance between pulmonary function testing and {sup 3}He-MRI was good, although subjective evaluation of {sup 3}He-MRI underestimated improvement in ventilation as obtained by pulmonary function tests. The {sup 3}He-MRI indicated OB in 6 cases. According to pulmonary function tests, BOS was diagnosed in 5 cases. All diagnoses of BOS were also detected by {sup 3}He-MRI. In 2 of these 5 cases, {sup 3}He-MRI indicated OB earlier than pulmonary function tests. The results support the hypothesis that {sup 3}He-MRI may be sensitive for early detection of OB and emphasize the need for larger prospective follow-up studies. (orig.)

  19. Development of a thermodynamic model for a cold cycle 3He-4He dilution refrigerator

    Science.gov (United States)

    Mueller, B. W.; Miller, F. K.

    2016-10-01

    A thermodynamic model of a 3He-4He cold cycle dilution refrigerator with no actively-driven mechanical components is developed and investigated. The refrigerator employs a reversible superfluid magnetic pump, passive check valves, a phase separation chamber, and a series of recuperative heat exchangers to continuously circulate 3He-4He and maintain a 3He concentration gradient across the mixing chamber. The model predicts cooling power and mixing chamber temperature for a range of design and operating parameters, allowing an evaluation of feasibility for potential 3He-4He cold cycle dilution refrigerator prototype designs. Model simulations for a prototype refrigerator design are presented.

  20. Diffusion weighted MRI and 18F-FDG PET/CT in non-small cell lung cancer (NSCLC): Does the apparent diffusion coefficient (ADC) correlate with tracer uptake (SUV)?

    Energy Technology Data Exchange (ETDEWEB)

    Regier, M., E-mail: mregier@uke.uni-hamburg.de [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Derlin, T. [Center for Radiology and Endoscopy, Department of Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Schwarz, D.; Laqmani, A.; Henes, F.O.; Groth, M.; Buhk, J.-H. [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Kooijman, H. [Philips Healthcare, Clinical Application, Luebeckertordamm 5, 20099 Hamburg (Germany); Adam, G. [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany)

    2012-10-15

    Introduction: To investigate the potential correlation of the apparent diffusion coefficient assessed by diffusion-weighted MRI (DWI) and glucose metabolism determined by the standardized uptake value (SUV) at 18F-FDG PET/CT in non-small cell lung cancer (NSCLC). Materials and methods: 18F-FDG PET/CT and DWI (TR/TE, 2000/66 ms; b-values, 0 and 500 s/mm{sup 2}) were performed in 41 consecutive patients with histologically verified NSCLC. Analysing the PET-CT data calculation of the mean (SUV{sub mean}) and maximum (SUV{sub max}) SUV was performed. By placing a region-of-interest (ROI) encovering the entire tumor mean (ADC{sub mean}) and minimum ADC (ADC{sub min}) were determined by two independent radiologists. Results of 18F-FDG PET-CT and DWI were compared on a per-patient basis. For statistical analysis Pearson's correlation coefficient, Bland–Altman and regression analysis were assessed. Results: Data analysis revealed a significant inverse correlation of the ADC{sub min} and SUV{sub max} (r = −0.46; p = 0.032). Testing the correlation of the ADC{sub min} and SUV{sub max} for each histological subtype separately revealed that the inverse correlation was good for both adenocarcinomas (r = −0.47; p = 0.03) and squamouscell carcinomas (r = −0.71; p = 0.002), respectively. No significant correlation was found for the comparison of ADC{sub min} and SUV{sub mean} (r = −0.29; p = 0.27), ADC{sub mean} vs. SUV{sub mean} (r = −0.28; p = 0.31) or ADC{sub mean} vs. SUV{sub max} (r = −0.33; p = 0.23). The κ-value of 0.88 indicated a good agreement between both observers. Conclusion: This preliminary study is the first to verify the relation between the SUV and the ADC in NSCLC. The significant inverse correlation of these two quantitative imaging approaches points out the association of metabolic activity and tumor cellularity. Therefore, DWI with ADC measurement might represent a new prognostic marker in NSCLC.

  1. Detection of D-^3He Fusion γ-Rays using Gas Cherenkov Detectors

    Science.gov (United States)

    Kim, Y.; Herrmann, H. W.; Mack, J. M.; Young, C. S.; Hale, G. M.; Evans, S. C.; Sedillo, T. J.; Cahill, A.; Horsfield, C. J.; Rubery, M. S.; Grafil, E.; Stoeffl, W.; Waugh, C.; Rinderknecht, H. G.; Frenje, J. A.; Petrasso, R. D.; Miller, E. Kirk

    2012-10-01

    The high-energy γ-ray from ^3He(d,γ)^5Li reactions has drawn the attention of the nuclear physics and fusion community as a diagnostic signature to study the ^5Li nuclear structure and the D-^3He fusion reaction. In the past, the D-^3He γ-rays have been measured via accelerator-based beam-target experiments and recently in tokamak-based fusion reactors. In this work, we report the detection of D-^3He fusion γ-rays generated from inertial confinement fusion (ICF) implosions at the OMEGA laser facility. The γ-ray signal observed using Gas Cherenkov Detectors (GCD) is proportional to the independently measured 14.7-MeV fusion proton yield and provides a high-bandwidth alternative to fusion protons for D-^3He burn-history measurements. By comparing γ-rays from D-^3He and D-T implosions, we were able to examine (1) similarities in the γ-ray spectra of D-^3He and D-T and (2) disparities in the γ-to-particle branching ratios of D-^3He and D-T. This experimental work motivates further theoretical investigation of the multichannel ^5Li- and ^5He-system.

  2. DC discharge characteristics and fluorine atom yield in NF3/He

    Institute of Scientific and Technical Information of China (English)

    Liping Duo; Shukai Tang; Haijun Yu; Jian Wang; Xiangde Min; Liucheng Li; Yuqi Jin; Bailing Yang; Fengting Sang

    2006-01-01

    @@ DC discharge characteristics of NF3/He have been investigated experimentally under different experimental conditions, for example, different electrode materials, separations, flow rates of the gas NF3 or He, and series resistances. The optimum discharge parameters and the fluorine atom yield from the DC discharge of NF3/He as function of load power are studied experimentally.

  3. A moving domain wall and order parameter orientation in 3He-B

    International Nuclear Information System (INIS)

    It is shown that movement of domain wall in the earlier considered two-domain structure in superfluid 3He β-phase eliminates the structure double degeneracy. It is suggested to use this fact for one-valued order parameter orientation in 3He-B

  4. First detection of 3He+ in the planetary nebula IC 418

    Science.gov (United States)

    Guzman-Ramirez, L.; Rizzo, J. R.; Zijlstra, A. A.; García-Miró, C.; Morisset, C.; Gray, M. D.

    2016-07-01

    The 3He isotope is important to many fields of astrophysics, including stellar evolution, chemical evolution, and cosmology. The isotope is produced in low-mass stars which evolve through the planetary nebula (PN) phase. 3He abundances in PNe can help test models of the chemical evolution of the Galaxy. We present the detection of the 3He+ emission line using the single dish Deep Space Station 63, towards the PN IC 418. We derived a 3He/H abundance in the range 1.74 ± 0.8 × 10-3 to 5.8 ± 1.7 × 10-3, depending on whether part of the line arises in an outer ionized halo. The lower value for 3He/H ratio approaches values predicted by stellar models which include thermohaline mixing, but requires that large amounts of 3He are produced inside low-mass stars which enrich the interstellar medium (ISM). However, this overpredicts the 3He abundance in H II regions, the ISM, and protosolar grains, which is known to be of the order of 10-5. This discrepancy questions our understanding of the evolution of the 3He, from circumstellar environments to the ISM.

  5. Possible Dimensional Crossover to 1D of ^3He Fluid in Nanochannels Observed in Susceptibilities

    Science.gov (United States)

    Matsushita, Taku; Kurebayashi, Katsuya; Shibatsuji, Ryosuke; Hieda, Mitsunori; Wada, Nobuo

    2016-05-01

    Dimensional crossover to the one-dimensional (1D) state from higher dimensions has been studied for dilute ^3He fluid adsorbed in 2.4 nm ^4He-preplated nanochannels, by susceptibility measurements down to 70 mK using 4.29 MHz nuclear magnetic resonance. In nanochannels, since energy states of ^3He motion perpendicular to the channel axis are discrete, a genuine 1D ^3He fluid is expected when the Fermi energy is less than the first excitation Δ _{01} for azimuthal motion. The susceptibilities χ above 0.3 K show the Curie-law susceptibilities independent of the ^3He density, which are characteristic of nondegenerate fluid in higher dimensions. With decreasing the temperature, a significant reduction of χ T was observed from about 0.3 K for all ^3He densities. It is considered to be due to the dimensional crossover below Δ _{01}˜ 0.5 K to the 1D ^3He state in the semi-degenerate regime above the Fermi temperature. In the 1D state at lower temperatures, T-independent χ were observed for ^3He of 0.019 layers below 0.1 K. It suggests that the 1D ^3He fluid enters the quantum degenerate regime.

  6. Towards the observation of the magnetic structure of solid 3He

    International Nuclear Information System (INIS)

    Experiments involving neutron scattering by 3He for which thermalization problems have been solved, along with the development of novel measurement techniques (density, magnetization, temperature) by polarized neutron transmission, crystallization experiments with 3He and 4He: a single crystal of helium have been obtained within a sintered metal in which the pore size is less than a micron are presented

  7. Burnup of fusion produced tritons and 3He ions in PLT and PDX

    International Nuclear Information System (INIS)

    The d(d,p)t and d(d,n)3He fusion reactions produce 1 MeV tritons and 0.8 MeV 3He ions which can subsequently undergo d(t,n)α and d(3He,p)α fusion reactions. The magnitude of this triton and 3He ion burnup was measured on the PLT and PDX tokamaks by detection of the 14 MeV neutron and 15 MeV proton emission. In discharges with B/sub phi/ greater than or equal to 2 T, the measured 3He burnup agrees well with predictions based on classical theories of ion confinement and slowing down, while the triton burnup was about four times lower than theoretically predicted. In discharges with weaker toroidal fields, the burnup of both ions fell by more than a factor of ten

  8. Electron bubbles and Weyl fermions in chiral superfluid 3He-A

    Science.gov (United States)

    Shevtsov, Oleksii; Sauls, J. A.

    2016-08-01

    Electrons embedded in liquid 3He form mesoscopic bubbles with large radii compared to the interatomic distance between 3He atoms, voids of Nbubble≈200 3He atoms, generating a negative ion with a large effective mass that scatters thermal excitations. Electron bubbles in chiral superfluid 3He-A also provide a local probe of the ground state. We develop a scattering theory of Bogoliubov quasiparticles by negative ions embedded in 3He-A that incorporates the broken symmetries of 3He-A , particularly broken symmetries under time reversal and mirror symmetry in a plane containing the chiral axis l ̂. Multiple scattering by the ion potential, combined with branch conversion scattering by the chiral order parameter, leads to a spectrum of Weyl fermions bound to the ion that support a mass current circulating the electron bubble—a mesoscopic realization of chiral edge currents in superfluid 3He-A films. A consequence is that electron bubbles embedded in 3He-A acquire angular momentum, L ≈-(Nbubble/2 ) ℏ l ̂ , inherited from the chiral ground state. We extend the scattering theory to calculate the forces on a moving electron bubble, both the Stokes drag and a transverse force, FW=e/c v ×BW , defined by an effective magnetic field, BW∝l ̂ , generated by the scattering of thermal quasiparticles off the spectrum of Weyl fermions bound to the moving ion. The transverse force is responsible for the anomalous Hall effect for electron bubbles driven by an electric field reported by the RIKEN group. Our results for the scattering cross section, drag, and transverse forces on moving ions are compared with experiments and shown to provide a quantitative understanding of the temperature dependence of the mobility and anomalous Hall angle for electron bubbles in normal and superfluid 3He-A . We also discuss our results in relation to earlier work on the theory of negative ions in superfluid 3He.

  9. PREFACE: JCNS Workshop on Modern Trends in Production and Applications of Polarized 3He

    Science.gov (United States)

    Ioffe, Alexander; Babcock, Earl; Gutberlet, Thomas

    2011-03-01

    Polarized neutron scattering techniques are an indispensable and highly requested tool for studying magnetic phenomena in condensed matter. The different coherent and incoherent scattering of isotopes such as protons and deuterons also allows applications of polarized neutrons in soft matter and biological studies of molecular and macromolecular dynamics. One method to polarize neutrons is to use polarized 3He gas which absorbs, or filters, one spin state of the neutron beam as it passes through it. Only about ten years ago, early polarized neutron scattering experiments using such 3He neutron spin filters (3He NSF) were being conducted using starting 3He polarizations of 55%. Currently there are two different commonly used methods to polarize high quantities of 3He. These methods both collisionally transfer spin polarization to ground state 3He nucleuses; one method uses optical pumping of an excited metastable state of 3He atoms, and the other uses optical pumping of the ground state of an alkali-metal vapour. Within the last decade immense progress in both methods has resulted in 3He polarizations of up to 80% being reported in atmosphere-pressure 3He cells by the world's leading labs. This progress in optical pumped 3He promises to give rise to much more efficient and novel polarized neutron scattering experiments as and also impacts other areas of science. Polarized 3He is additionally applied in research fields such as particle physics, fundamental studies and medicine. Thus not only the techniques and methods of polarization, but the research groups themselves exploring polarized 3He, have a large breadth and diversity spanning different fields of science and locations in the world. Given this diversity, it is rare for this community to meet as a group at any one meeting or conference. Because it is crucial to discuss new developments in 3He polarization in a multi-disciplinary international setting, an international workshop on "Modern Trends in Production

  10. Gas cells for 3He hyperpolarized via spin-exchange optical pumping

    Science.gov (United States)

    Kim, W.; Stepanyan, S. S.; Kim, A.; Tan, J. A.; Woo, S.

    2016-01-01

    We present a device for the production of hyperpolarized 3He, which is widely used in spinrelated nuclear physics research. Spin-exchange optical pumping (SEOP) is employed to polarize 3He enclosed in a circular borosilicate glass cell suitable not only for the production of polarized gas but also for its storage. The portable glass cell can, thus, be transported to any other research facility. The glass cell can be refilled several times. Special attention is given to the preparation and the filling of the cell to minimize the impurities on its walls and in the gas. We employ glass tubes with shorter lengths and larger diameters in the gas-filling system to achieve the improvement in the air flow necessary to obtain purer polarized 3He samples. The cell is prepared, and after it has been filled with rubidium (Rb) and 3He-N2 mixture, it is sealed under high vacuum conditions. The cell containing the mixture is exposed to circularly-polarized laser light with a wavelength of 795 nm at temperatures of 180 - 220 °C for SEOP. The polarization of 3He is measured via nuclear magnetic resonance (NMR). We obtained 40% polarized 3He in less than 15 hours and 50% in about 25 hours. The longitudinal relaxation time T 1 of the polarized 3He we measured was about 58 hours.

  11. First Detection of $^3$He$^+$ in the Planetary Nebula IC$\\,$418

    CERN Document Server

    Guzman-Ramirez, L; Zijlstra, A A; García-Miró, C; Morisset, C; Gray, M D

    2016-01-01

    The $^3$He isotope is important to many fields of astrophysics, including stellar evolution, chemical evolution, and cosmology. The isotope is produced in low-mass stars which evolve through the planetary nebula (PN) phase. $^3$He abundances in PNe can help test models of the chemical evolution of the Galaxy. We present the detection of the $^3$He$^+$ emission line using the single dish Deep Space Station 63, towards the PN IC$\\,$418. We derived a $^3$He/H abundance in the range 1.74$\\pm$0.8$\\times$10$^{-3}$ to 5.8$\\pm$1.7$\\times$10$^{-3}$, depending on whether part of the line arises in an outer ionized halo. The lower value for $^3$He/H ratio approaches values predicted by stellar models which include thermohaline mixing, but requires that large amounts of $^3$He are produced inside low-mass stars which enrich the interstellar medium (ISM). However, this over-predicts the $^3$He abundance in HII regions, the ISM, and proto-solar grains, which is known to be of the order of 10$^{-5}$. This discrepancy questi...

  12. 3He(d,p)4He reaction calculation with three-body Faddeev equations

    International Nuclear Information System (INIS)

    In order to investigate the 3He-n-p system as a three-body problem, we have formulated 3He-n and 3H-p effective potentials using both a microscopic treatment and a phenomenological approach. In the microscopic treatment, potentials are generated by means of the resonating group method (RGM) based on the Minnesota nucleon-nucleon potential. These potentials are converted into separable form by means of the microscopic Pauli correct (MPC) method. The MPC potentials are properly formulated to avoid Pauli forbidden states. The phenomenological potentials are obtained by modifying parameters of the EST approximation to the Paris nucleon-nucleon potential, such that they fit the low-energy 3He-n, 3H-p, and 3He-p phase shifts. Therefore, they describe the 3He-n differential cross section, the polarization observables, and the energy levels of 4He. The 3He-n-p Faddeev equations are solved numerically. We reproduce correctly the ground state and the first excited state of 5Li. Furthermore, the Paris-type potential is used to investigate the 3He(d,p)4He reaction at a deuteron bombarding energy of 270 MeV, where the system is treated as a three-body problem. Results for the polarized and unpolarized differential cross sections demonstrate convergence of the Born series. (orig.)

  13. Evidence of Cluster Structure of $^9$Be from $^3$He+$^9$Be Reaction

    CERN Document Server

    Lukyanov, S M; Naumenko, M A; Xu, Yi; Trzaska, W H; Burjan, V; Kroha, V; Mrazek, J; Glagolev, V; Piskoř, Š; Voskoboynik, E I; Khlebnikov, S V; Penionzhkevich, Yu E; Skobelev, N K; Sobolev, Yu G; Tyurin, G P; Kuterbekov, K; Tuleushev, Yu

    2015-01-01

    The study of inelastic scattering and multi-nucleon transfer reactions was performed by bombarding a $^{9}$Be target with a $^3$He beam at an incident energy of 30 MeV. Angular distributions for $^9$Be($^3$He,$^3$He)$^{9}$Be, $^9$Be($^3$He,$^4$He)$^{8}$Be, $^9$Be($^3$He,$^5$He)$^{7}$Be, $^9$Be($^3$He,$^6$Li)$^6$Li and $^9$Be($^3$He,$^5$Li)$^7$Li reaction channels were measured. Experimental angular distributions for the corresponding ground states (g.s.) were analysed within the framework of the optical model, the coupled-channel approach and the distorted-wave Born approximation. Cross sections for channels leading to unbound $^5$He$_{g.s.}$, $^5$Li$_{g.s.}$ and $^8$Be systems were obtained from singles measurements where the relationship between the energy and the scattering angle of the observed stable ejectile is constrained by two-body kinematics. Information on the cluster structure of $^{9}$Be was obtained from the transfer channels. It was concluded that cluster transfer is an important mechanism in t...

  14. Study on (n3, He) fusion reactions cross sections using optical model

    International Nuclear Information System (INIS)

    Non-elastic cross-sections have been calculated by using optical model for (n3, He) reactions at 22.5 MeV energy. The empirical formula including optical model non-elastic effects by fitting two parameters for the (n3, He) reaction cross-sections have been suggested. Reaction Q-values depending on the asymmetry term effect for the (n3, He) reaction have been investigated. The obtained cross-section formula with new coefficients has been compared with the experimental data and discussed. It has seen that the fit of formula in this paper is in good agreement with the experimental data

  15. New data and evaluation of sup 3 He-induced nuclear reactions on Cu

    CERN Document Server

    Tarkanyi, F; Takács, S; Al-Abyad, M; Mustafa, M G; Shubin, Y; Zhuang, Y

    2002-01-01

    Excitation functions of sup n sup a sup t Cu( sup 3 He, x) sup 6 sup 6 Ga, sup n sup a sup t Cu( sup 3 He, x) sup 6 sup 7 Ga, sup n sup a sup t Cu( sup 3 He, x) sup 6 sup 3 Zn and sup n sup a sup t Cu( sup 3 He, x) sup 6 sup 5 Zn nuclear reactions were measured up to 36 MeV using stacked foil irradiation arrangement and activation technique. The results were compared with compiled literature data. The status of the experimental database was investigated with the goal to produce recommended values for different applications. The application of the deduced data in the field of beam monitoring and thin layer activation is discussed.

  16. The ion optics of a miniature 3He/4He mass spectrometer of high resolution

    International Nuclear Information System (INIS)

    To measure the isotopic abundance ratio of 3He and 4He in samples by mass spectrometers is an important detection mean for helium isotope geochemistry research. A symmetrically arranged tandem 3He/4He mass spectrometer is described in the paper. The front stage, used to analyse 3He (including HD and H3) and 4He, is a homogeneous analysing magnet with a bending angle of 90 deg and a bending radius of 6 cm. The end stage, used to analyse 3He, HD and H3, is a non-homogeneous analysing magnet with a bending angle of 180 deg, a bending radius of 15 cm and a magnetic field gradient of 0.75. Because of the use of the non-zero second order coefficient β and curved entrance face of the later magnet for eliminating second order aberrations, the resolving power of the system is notably improved, and theoretically reaches about 3800

  17. Core Plasma Characteristics of a Spherical Tokamak D-3He Fusion Reactor

    Institute of Scientific and Technical Information of China (English)

    Shi Bingren

    2005-01-01

    The magnetic fusion reactor using the advanced D-3He fuels has the advantage of much less-neutron productions so that the consequent damages to the first wall are less serious. If the establishment of this kind of reactor becomes realistic, the exploration of 3He on the moon will be largely motivated. Based on recent progresses in the spherical torus (ST) research, we have physically designed a D-3He fusion reactor using the extrapolated results from the ST experiments and also the present-day tokamak scaling. It is found that the reactor size significantly depends on the wall reflection coefficient of the synchrotron radiation and of the impurity contaminations.The secondary reaction between D-D that promptly leads to the D-T reaction producing 14 MeV neutrons is also estimated. Comparison of this D-3He ST reactor with the D-T reactor is made.

  18. Measurements of the structure and nucleation of vorticity in the (3)He superfluids. Doctoral thesis

    Energy Technology Data Exchange (ETDEWEB)

    Parts, U.

    1995-10-01

    This thesis reports experiments on rotating superfluid 3He, which were performed in the Low Temperature Laboratory during the period 1991-94, and which are published in a series of original publications. Rotation is particularly useful for creating various types of topological objecs, e.g. quantized vortex lines, in large quantities for systematic investigation. The author`s method to study them is the nuclear magnetic resonance (NMR) technique, which has been an important experimental tool in various fields of physics for about fifty years. In the case of superfluid 3He, NMR provides direct information on the spatial distribution of the order parameter field. Both superfluid phases of 3He, the A- and the B-phase, have been under investigation in this thesis work. In 3He-B the main concern has been the nucleation of singular vortices. This process involves an energy barrier, similar to a first order phase transition.

  19. Hyperpolarized 3He MRI and 81mKr SPECT in chronic obstructive pulmonary disease

    DEFF Research Database (Denmark)

    Stavngaard, Trine; Søgaard, Lise; Mortensen, J;

    2005-01-01

    was to compare ventilation imaging methods in 26 patients with chronic obstructive pulmonary disease (COPD) and nine lung healthy volunteers. METHODS: HP 3He MRI, 81mKr single-photon emission computed tomography (SPECT), high-resolution computed tomography (HRCT) and pulmonary function tests were performed....... The three scans were scored visually as percentage of non-ventilated/diseased lung, and a computer-based objective measure of the ventilated volume in HP 3He MRI and 81mKr SPECT and an emphysema index in HRCT were calculated. RESULTS: We found a good correlation between HP 3He MRI and 81mKr SPECT for both...... visual defect score (r=0.80, pKr SPECT (the score on HP 3He MRI...

  20. Discovery of superfluid 3He phases wins 1996 nobel prize in physics

    International Nuclear Information System (INIS)

    The 1996 Nobel prize in physics was awarded to David M. Lee, Douglas D. Osheroff and Robert C. Richardson for their discovery of superfluidity in 3He in 1971. A short account of the discovery and its importance is given

  1. Cryopol: a superconducting magnetostatic cavity for a sup 3 He neutron spin filter

    CERN Document Server

    Dreyer, J; Bourgeat-Lami, E; Lelievre-Berna, E; Pujol, S; Thomas, F; Thomas, M; Tasset, F

    2000-01-01

    We present a device called 'Cryopol' that provides a clean magnetic environment for a sup 3 He spin filter cell, even in the presence of strong magnetic stray fields like those of a superconducting magnet.

  2. 3He spin filters for a thermal neutron triple axis spectrometer

    Science.gov (United States)

    Chen, W. C.; Armstrong, G.; Chen, Y.; Collett, B.; Erwin, R.; Gentile, T. R.; Jones, G. L.; Lynn, J. W.; McKenney, S.; Steinberg, J. E.

    2007-07-01

    We have tested two 3He neutron spin filters (NSF), one for the polarizer and one for the analyzer, in conjunction with a doubly focusing pyrolytic graphite (PG) monochromator on the state-of-the-art BT-7 thermal triple axis spectrometer (TAS) at the National Institute of Standards and Technology (NIST) Center for Neutron Research (NCNR). This system will provide significantly better neutronic performance for polarization analysis over a conventional TAS with Heusler crystals. We discuss the scheme for employing NSFs on the TAS instrument, including the 3He cell design, spin-exchange optical pumping (SEOP) of these large 3He cells, and the holding fields on the spectrometer. Using Rb/K hybrid SEOP, we have produced 75% 3He polarization for the 11 cm diameter cells for TAS in less than two days.

  3. Precise tests of fundamental symmetries at low energies using a {sup 3}He-{sup 129}Xe comagnetometer

    Energy Technology Data Exchange (ETDEWEB)

    Allmendinger, Fabian

    2015-01-21

    Effects of theories beyond the Standard Model would become directly apparent at high energies, which are probably out of reach for colliders. As an alternative, low-energy high-precision measurements of quantities are performed, looking for deviations from the Standard Model (SM) predictions. In this case: Firstly, a small amount of the large effects of quantum gravity at the Planck scale should remain at low energies, which is tested by looking for Lorentz invariance violation in the neutron sector. Secondly, new sources of CP-violation would cause permanent electric dipole moments (EDMs)of particles that are many orders of magnitude larger than the EDMs predicted by the SM. The experimental approach is to measure the free precession of nuclear spin polarized {sup 3}He and {sup 129}Xe atoms in a homogeneous magnetic guiding field of about 400 nT using LT{sub C} SQUIDs as low-noise magnetic flux detectors. This dissertation reports on the search for a CPT and Lorentz invariance violating coupling of the {sup 3}He and {sup 129}Xe nuclear spins to posited background fields. An upper limit on the equatorial component of the background field interacting with the spin of the bound neutron b{sup n} {sub perpendicular} {sub to} <8.4.10{sup -34} GeV (68% C.L.) was obtained. Furthermore, the technical developments and preparations for measurements of the {sup 129}Xe EDM are described.

  4. High-efficiency microstructured semiconductor neutron detectors for direct 3He replacement

    International Nuclear Information System (INIS)

    High-efficiency Microstructured Semiconductor Neutron Detectors (MSNDs) have been tiled and arranged in a cylindrical form factor in order to serve as a direct replacement to aging and increasingly expensive 3He gas-filled proportional neutron detectors. Two 6-in long by 2-in diameter cylinders were constructed and populated with MSNDs which were then directly compared to a 4 atm Reuter Stokes 3He detector of the same dimensions. The Generation 1 MSND-based 3Helium-Replacement (HeRep Mk I) device contained sixty-four 1-cm2 active-area MSNDs, each with an intrinsic neutron detection efficiency of approximately 7%. A Generation 2 device (the HeRep Mk II) was populated with thirty 4-cm2 active-area MSNDs, with an intrinsic thermal neutron detection efficiency of approximately 30%. The MSNDs of each HeRep were integrated to count as a single device. The 3He proportional counter and the HeRep devices were tested while encased in a cylinder of high-density polyethylene measuring a total of 6-in by 9-in. The 3He counter and the HeRep Mk II were each placed 1 m from a 54-ng 252Cf source and tested for efficiency. The 3He proportional counter had a net count rate of 17.13±0.10 cps at 1 m. The HeRep Mk II device had a net count rate of 17.60±0.10 cps, amounting to 102.71±2.65% of the 3He gas counter while inside of the moderator. Outside of moderator, the 3He tube had a count rate of 3.35±0.05 cps and the HeRep Mk II device reported 3.19±05, amounting to 95.15±9.04% of the 3He neutron detector

  5. A compact SEOP 3He neutron spin filter with AFP NMR

    Science.gov (United States)

    Ino, Takashi; Arimoto, Yasushi; Shimizu, Hirohiko M.; Sakaguchi, Yoshifumi; Sakai, Kenji; Kira, Hiroshi; Shinohara, Takenao; Oku, Takayuki; Suzuki, Jun-ichi; Kakurai, Kazuhisa; Chang, Lieh-Jeng

    2012-02-01

    We developed AFP NMR in an aluminum container for polarized noble gas nuclei. The radio frequency magnetic field inside the aluminum container was designed from computer simulations. The polarization loss by the AFP spin flip of 3He was measured to be as low as 3.8×10-4. With this technique, a compact in-situ polarizing 3He neutron spin filter with AFP NMR is demonstrated.

  6. {sup 3}He spectrum at small atmospheric depths for different geomagnetic cutoff values

    Energy Technology Data Exchange (ETDEWEB)

    Papini, P. [Florence Univ. (Italy)]|[INFN, Florence (Italy); Grimani, C. [Perugia Univ. (Italy)]|[INFN, Perugia (Italy); Stephens, S.A. [Tata Institute of Fundamental Research, Bombay (International Commission on Radiation Units and Measurements)

    1995-09-01

    It is carried out a calculation to determine the energy spectra of secondary {sup 3}He at small atmospheric depths. It is produced in the spallation reaction of primary helium and heavier nuclei in the overlying atmosphere. It is examined the effect of the geomagnetic cut-off on the spectral shape of the secondary {sup 3}He nuclei. The calculations are being carried out for both solar minimum and maximum periods. Results from these calculations will be presented at the Conference.

  7. Improved Technique for Measurement of Regional Fractional Ventilation by Hyperpolarized 3He MRI

    OpenAIRE

    Emami, Kiarash; Kadlecek, Stephen J.; Woodburn, John M.; Zhu, Jianliang; Yu, Jiangsheng; Vahdat, Vahid; Pickup, Stephen; Ishii, Masaru; Rizi, Rahim R.

    2010-01-01

    Quantitative measurement of regional lung ventilation is of great significance in assessment of lung function in many obstructive and restrictive pulmonary diseases. A new technique for regional measurement of fractional ventilation using hyperpolarized 3He MRI is proposed, addressing the shortcomings of an earlier approach that limited its use to small animals. The new approach allows for the acquisition of similar quantitative maps over a shortened period and requires substantially less 3He...

  8. Possibilities for breakeven and ignition of D-3He fusion fuel in a near term tokamak

    International Nuclear Information System (INIS)

    The recent realization that the moon contains a large amount of the isotope 3He has rekindled interest in the D-3He fuel cycle. In this study we consider the feasibility of investigating D-3He reactor plasma conditions in a tokamak of the NET/INTOR class. We have found that, depending on the energy confinement scaling law, energy breakeven may be achieved without significant modification to the NET design. The best results are for the more optimistic ASDEX H-mode scaling law. Kaye-Goldston scaling with a modest improvement due to the H-mode is more pessimistic and makes achieving breakeven more difficult. Significant improvement in Q (ratio of the fusion power to the injected power), or the ignition margin, can be achieved by taking advantage of the much reduced neutron production of the D-3He fuel cycle. Removal of the tritium producing blanket and replacing the inboard neutron shield by a thinner shield optimized for the neutron spectrum in D-3He allows the plasma to be increased without changing the magnetic field at the toroidal field magnet. This allows the plasma to achieve higher beta and Q values up to about 3. The implications of D-3He operation for fast ion loss, neutron shielding, heat loads on the first wall and divertor, plasma refuelling, changes to the poloidal field coil system, and pumping of the helium from the vacuum chamber are considered in the report. (orig.)

  9. First doubly polarised photoproduction on 3He at the photon beam of MAMI

    International Nuclear Information System (INIS)

    A first experiment with a polarised 3He target was carried out in July 2009 at the MAMI accelerator in Mainz in a photon energy range between 200 MeV and 800 MeV. The aim of this measurement was to investigate the Gerasimov-Drell-Hearn sum rule on the neutron. The use of the data obtained with the polarised 3He target, compared to existing data on the deuteron, gives a complementary and more direct access to the neutron, due to the spin structure of the 3He. The measurement of the helicity dependence of the inclusive total photoabsorption cross section required a beam of tagged circularly polarised photons incident on the longitudinally polarised 3He target. The data were taken using the 4π Crystal Ball photon spectrometer in combination with TAPS as a forward wall and complemented by a threshold Cherenkov detector used to on-line suppress the background from electromagnetic events. The development and preparation of the different components of the 3He experimental setup was an important part of this work and are described in detail in this thesis. The detector system and the analysis method were tested by the measurement of the unpolarised total inclusive photoabsorption cross section on liquid hydrogen. The results obtained are in good agreement with previous published data. Preliminary results of the unpolarised total photoabsorption cross section, as well as the helicity dependent photoabsorption cross section difference on 3He compared with several theoretical models will also be presented. (orig.)

  10. Polarized 3He+2 ions in the Alternate Gradient Synchrotron to RHIC transfer line

    Science.gov (United States)

    Tsoupas, N.; Huang, H.; Méot, F.; Ptitsyn, V.; Roser, T.; Trbojevic, D.

    2016-09-01

    The proposed electron-hadron collider (eRHIC) to be built at Brookhaven National Laboratory (BNL) will allow the collisions of 20 GeV polarized electrons with 250 GeV polarized protons, or 100 GeV /n polarized 3He+2 ions, or other unpolarized ion species. The large value of the anomalous magnetic moment of the 3He nucleus GHe=(g -2 )/2 =-4.184 (where g is the g -factor of the 3He nuclear spin) combined with the peculiar layout of the transfer line which transports the beam bunches from the Alternate Gradient Synchrotron (AGS) to the Relativistic Heavy Ion Collider (RHIC) makes the transfer and injection of polarized 3He ions from AGS to RHIC (AtR) a special case as we explain in the paper. Specifically in this paper we calculate the stable spin direction of a polarized 3He beam at the exit of the AtR line which is also the injection point of RHIC, and we discuss a simple modifications of the AtR beam-transfer-line, to perfectly match the stable spin direction of the injected polarized 3He beam to that of the circulating beam, at the injection point of RHIC.

  11. Difusividade térmica aparente de sementes de cajá em temperaturas acima do congelamento até ultrabaixas temperaturas Apparent thermal diffusivity of caja seeds in above freezing to ultra low temperatures

    Directory of Open Access Journals (Sweden)

    Marcos J. de A. Gama

    2012-01-01

    Full Text Available O objetivo do trabalho foi determinar a difusividade térmica aparente de sementes de cajá avaliando o efeito da variação do teor de água e da temperatura e ajustar diferentes modelos matemáticos aos valores experimentais. Sementes com a faixa de teor de água de 6,05 a 61,84% (b.u. foram submetidas a secagem e à temperatura de 40 ºC. A redução do teor de água ao longo da secagem foi acompanhada pelo método gravimétrico (perda de massa enquanto a difusividade térmica aparente da semente de cajá foi determinada pelo método de Dickerson. Concluiu-se que a difusividade térmica aparente, em temperatura acima do congelamento e em ultrabaixas temperaturas em função do teor de água (b.u, podem ser representados satisfatoriamente por um modelo de regressão linear e que o valor da difusividade térmica aparente aumenta exponencialmente com o aumento da temperatura.The aim of this study was to determine experimentally the apparent thermal diffusivity caja seeds, evaluating the effect of variation of water content and temperature and adjust different mathematical models to experimental values. Seeds with the range of water content from 6.05 to 61.84% (wb subjected to drying at a temperature of 40 ºC were studied. The reduction of water content during drying was monitored by gravimetric method (weight loss. The apparent thermal diffusivity of caja seed was determined by the method of Dickerson. It was concluded that the apparent thermal diffusivity in temperature above freezing and ultralow temperatures as a function of water content (wb, can be satisfactorily represented by a linear regression model and that value of the apparent thermal diffusivity increases exponentially with increasing temperature.

  12. Terrestrial cosmogenic 3He: where are we 30 years after its discovery?

    Science.gov (United States)

    Blard, Pierre-Henri; Pik, Raphaël; Farley, Kenneth A.; Lavé, Jérôme; Marrocchi, Yves

    2016-04-01

    It is now 30 years since cosmogenic 3He has been detected for the first time in a terrestrial sample (Kurz, 1986). 3He is now a widely used geochemical tool in many fields of Earth sciences: volcanology, tectonics, paleoclimatology. 3He has the advantage to have a high "production rate" to "detection limit" ratio, allowing surfaces as young as hundred of years to be dated. Although its nuclear stability implies several limitations, it moreover represents a useful alternative to 10Be in mafic environments. This contribution is a review of the progresses that have been accomplished since this discovery, and discuss strategies to improve both the accuracy and the precision of this geochronometer. 1) Measurement of cosmogenic 3He Correction of magmatic 3He. To estimate the non-cosmogenic magmatic 3He, Kurz (1986) invented a two steps method involving crushing of phenocrysts (to analyze the isotopic ratio of the magmatic component), followed by a subsequent melting of the sample, to extract the remaining components, including the cosmogenic 3He: 3Hec = 3Hemelt -4Hemelt x (3He/4He)magmatic (1) Several studies suggested that the preliminary crushing may induce a loss of cosmogenic 3He (Hilton et al., 1993; Yokochi et al., 2005; Blard et al., 2006), implying an underestimate of the cosmogenic 3He measurement. However, subsequent work did not replicate these observations (Blard et al., 2008; Goerhing et al., 2010), suggesting an influence of the used apparatus. An isochron method (by directly melting several phenocrysts aliquots) is an alternative to avoid the preliminary crushing step (Blard and Pik, 2008). Atmospheric contamination. Protin et al. (in press) provides robust evidences for a large and irreversible contamination of atmospheric helium on silicate surfaces. This unexpected behavior may reconcile the contrasted observations about the amplitude of crushing loss. This undesirable atmospheric contamination is negligible if grain fractions smaller than 150 mm are

  13. Terrestrial cosmogenic 3He: where are we 30 years after its discovery?

    Science.gov (United States)

    Blard, Pierre-Henri; Pik, Raphaël; Farley, Kenneth A.; Lavé, Jérôme; Marrocchi, Yves

    2016-04-01

    It is now 30 years since cosmogenic 3He has been detected for the first time in a terrestrial sample (Kurz, 1986). 3He is now a widely used geochemical tool in many fields of Earth sciences: volcanology, tectonics, paleoclimatology. 3He has the advantage to have a high "production rate" to "detection limit" ratio, allowing surfaces as young as hundred of years to be dated. Although its nuclear stability implies several limitations, it moreover represents a useful alternative to 10Be in mafic environments. This contribution is a review of the progresses that have been accomplished since this discovery, and discuss strategies to improve both the accuracy and the precision of this geochronometer. 1) Measurement of cosmogenic 3He Correction of magmatic 3He. To estimate the non-cosmogenic magmatic 3He, Kurz (1986) invented a two steps method involving crushing of phenocrysts (to analyze the isotopic ratio of the magmatic component), followed by a subsequent melting of the sample, to extract the remaining components, including the cosmogenic 3He: 3Hec = 3Hemelt ‑4Hemelt x (3He/4He)magmatic (1) Several studies suggested that the preliminary crushing may induce a loss of cosmogenic 3He (Hilton et al., 1993; Yokochi et al., 2005; Blard et al., 2006), implying an underestimate of the cosmogenic 3He measurement. However, subsequent work did not replicate these observations (Blard et al., 2008; Goerhing et al., 2010), suggesting an influence of the used apparatus. An isochron method (by directly melting several phenocrysts aliquots) is an alternative to avoid the preliminary crushing step (Blard and Pik, 2008). Atmospheric contamination. Protin et al. (in press) provides robust evidences for a large and irreversible contamination of atmospheric helium on silicate surfaces. This unexpected behavior may reconcile the contrasted observations about the amplitude of crushing loss. This undesirable atmospheric contamination is negligible if grain fractions smaller than 150 mm are

  14. Development of a 3He/Xe gas scintillation counter to measure the 3He(n,p)T cross section in the intermediate energy range

    International Nuclear Information System (INIS)

    A 3He/Xe gas scintillation counter has been developed for measuring the neutron energy range from thermal to 3 MeV. Great effort was concentrated on improving the detector design to optimize light production and collection to improve the energy resolution which is primarily controlled by photon statistics. The detectors were tested using a 238Pu alpha-particle source, a thermal neutron beam from the NBS reactor, and the white-neutron spectrum from the NBS linac. The detector measures an energy resolution of 17 % (FWHM) for the 3He(n,p)T reaction at 2.0 MeV which is sufficient for cross section measurement. (author)

  15. Development of a 3He/Xe gas scintillation counter to measure the 3He(n,p)T cross section in the intermediate energy range

    International Nuclear Information System (INIS)

    A 3He/Xe gas scintillation counter has been developed for measuring the neutron energy range from thermal to 3 MeV. Great effort was concentrated on improving the detector design to optimize light production and collection to improve the energy resolution which is primarily controlled by photon statistics. The detectors were tested using a 238Pu alpha-particle source, a thermal neutron beam from the NBS reactor, and the white-neutron spectrum from the NBS linac. The detector measures an energy resolution of 17% (FWHM) for the 3He(n,p)T reaction at 2.0 MeV which is sufficient for cross section measurement. 12 refs., 8 figs

  16. Photodisintegration of /sup 3/H and /sup 3/He. [Threshold to 25 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Faul, D.D.

    1980-09-01

    The photoneutron cross sections for /sup 3/H and /sup 3/He have been measured from threshold to approx. 25 MeV with monoenergetic photons from the annihilation in flight of fast positrons at the LLL Electron-Positron Linear Accelerator facility. These reactions include the two-body breakup of /sup 3/H and the three-body breakup of both /sup 3/H and /sup 3/He; these measurements for /sup 3/H are the first to span the energy region across the peaks of the cross sections. An efficient BF/sub 3/-tube-and-paraffin neutron detector and high-pressure gaseous samples of several moles each (the activity of the /sup 3/H sample was approx. 200,000 Ci) were employed in these measurements. Measurements on /sup 16/O and /sup 2/H also were performed to verify the absolute cross-section scale. The results, when compared with each other and with results for the two-body breakup cross section for /sup 3/He from the literature, show that the two-body breakup cross sections for /sup 3/H and /sup 3/He have nearly the same shape, but the one for /sup 3/He lies lower in magnitude; the three-body breakup cross section for /sup 3/He lies higher in magnitude and is broader in the peak region and also rises less sharply from threshold than that for /sup 3/H; and these measured differences between the cross sections for the breakup modes largely compensate in their sum, so that the total photon absorption cross sections for /sup 3/H and /sup 3/He are nearly the same in both size and shape at energies near and above their peaks. Theoretical results from the literature disagree with the experimental results to a certain extent over the entire photon-energy region for which the photoneutron cross sections were measured. 50 figures, 7 tables.

  17. Coherent deeply virtual Compton scattering off 3He and neutron generalized parton distributions

    CERN Document Server

    Rinaldi, Matteo

    2014-01-01

    It has been recently proposed to study coherent deeply virtual Compton scattering (DVCS) off 3He nuclei to access neutron generalized parton distributions (GPDs). In particular, it has been shown that, in Impulse Approximation (IA) and at low momentum transfer, the sum of the quark helicity conserving GPDs of 3He, H and E, is dominated by the neutron contribution. This peculiar result makes the 3He target very promising to access the neutron information. We present here the IA calculation of the spin dependent GPD tilde-H of 3He. Also for this quantity the neutron contribution is found to be the dominant one, at low momentum transfer. The known forward limit of the IA calculation of tilde-H, yielding the polarized parton distributions of 3He, is correctly recovered. The extraction of the neutron information could be anyway non trivial, so that a procedure, able to take into account the nuclear effects encoded in the IA analysis, is proposed. These calculations, essential for the evaluation of the coherent DVC...

  18. Oxygen-sensitive {sup 3}He-MRI in bronchiolitis obliterans after lung transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Gast, Klaus K. [Klinikum der Johannes Gutenberg-Universitaet, Klinik und Poliklinik fuer diagnostische und interventionelle Radiologie, Mainz (Germany); Biedermann, Alexander [Klinikum der Johannes Gutenberg-Universitaet, 3. Medizinische Klinik, Pulmonologie, Mainz (Germany); Herweling, Annette [Klinikum der Johannes Gutenberg-Universitaet, Klinik fuer Anaesthesiologie, Mainz (Germany); Schreiber, Wolfgang G. [Klinikum der Johannes Gutenberg-Universitaet, Klinik und Poliklinik fuer diagnostische und interventionelle Radiologie, MR-Physik, Mainz (Germany); Schmiedeskamp, Joerg [Max-Planck-Institut fuer Polymerforschung, Mainz (Germany); Mayer, Eckhard [Klinikum der Johannes Gutenberg-Universitaet, Klinik fuer Herz-, Thorax- und Gefaesschirurgie, Mainz (Germany); Heussel, Claus P. [Abteilung fuer Radiologie, Thoraxklinik Heidelberg, Heidelberg (Germany); Markstaller, Klaus; Eberle, Balthasar [Inselspital/Universitaetsspital, Klinik fuer Anaesthesiologie, Bern (Switzerland); Kauczor, Hans-Ulrich [Radiologie, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg (Germany)

    2008-03-15

    Oxygen-sensitive {sup 3}He-MRI was studied for the detection of differences in intrapulmonary oxygen partial pressure (pO{sub 2}) between patients with normal lung transplants and those with bronchiolitis obliterans syndrome (BOS). Using software developed in-house, oxygen-sensitive {sup 3}He-MRI datasets from patients with normal lung grafts (n = 8) and with BOS (n = 6) were evaluated quantitatively. Datasets were acquired on a 1.5-T system using a spoiled gradient echo pulse sequence. Underlying diseases were pulmonary emphysema (n = 10 datasets) and fibrosis (n = 4). BOS status was verified by pulmonary function tests. Additionally, {sup 3}He-MRI was assessed blindedly for ventilation defects. Median intrapulmonary pO{sub 2} in patients with normal lung grafts was 146 mbar compared with 108 mbar in patients with BOS. Homogeneity of pO2 distribution was greater in normal grafts (standard deviation pO2 34 versus 43 mbar). Median oxygen decrease rate during breath hold was higher in unaffected patients (-1.75 mbar/s versus -0.38 mbar/s). Normal grafts showed fewer ventilation defects (5% versus 28%, medians). Oxygen-sensitive {sup 3}He-MRI appears capable of demonstrating differences of intrapulmonary pO2 between normal lung grafts and grafts affected by BOS. Oxygen-sensitive {sup 3}He-MRI may add helpful regional information to other diagnostic techniques for the assessment and follow-up of lung transplant recipients. (orig.)

  19. Coherent deeply virtual Compton scattering off 3He and neutron generalized parton distributions

    Directory of Open Access Journals (Sweden)

    Rinaldi Matteo

    2014-06-01

    Full Text Available It has been recently proposed to study coherent deeply virtual Compton scattering (DVCS off 3He nuclei to access neutron generalized parton distributions (GPDs. In particular, it has been shown that, in Impulse Approximation (IA and at low momentum transfer, the sum of the quark helicity conserving GPDs of 3He, H and E, is dominated by the neutron contribution. This peculiar result makes the 3He target very promising to access the neutron information. We present here the IA calculation of the spin dependent GPD H See Formula in PDF of 3He. Also for this quantity the neutron contribution is found to be the dominant one, at low momentum transfer. The known forward limit of the IA calculation of H See Formula in PDF , yielding the polarized parton distributions of 3He, is correctly recovered. The extraction of the neutron information could be anyway non trivial, so that a procedure, able to take into account the nuclear effects encoded in the IA analysis, is proposed. These calculations, essential for the evaluation of the coherent DVCS cross section asymmetries, which depend on the GPDs H,E and H See Formula in PDF , represent a crucial step for planning possible experiments at Jefferson Lab.

  20. Multi-Spacecraft Observations of Recurrent 3He-Rich Solar Energetic Particles

    CERN Document Server

    Bucik, R; Mall, U; Korth, A; Mason, G M; Gomez-Herrero, R

    2014-01-01

    We study the origin of 3He-rich solar energetic particles (<1 MeV/nucleon) that are observed consecutively on STEREO-B, ACE, and STEREO-A spacecraft when they are separated in heliolongitude by more than 90{\\deg}. The 3He-rich period on STEREO-B and STEREO-A commences on 2011 July 1 and 2011 July 16, respectively. The ACE 3He-rich period consists of two sub-events starting on 2011 July 7 and 2011 July 9. We associate the STEREO-B July 1 and ACE July 7 3He-rich events with the same sizeable active region producing X-ray flares accompanied by prompt electron events, when it was near the west solar limb as seen from the respective spacecraft. The ACE July 9 and STEREO-A July 16 events were dispersionless with enormous 3He enrichment, lacking solar energetic electrons and occurring in corotating interaction regions. We associate these events with a small, recently emerged active region near the border of a low-latitude coronal hole that produced numerous jet-like emissions temporally correlated with type III r...

  1. Results on Double-polarization Asymmetries in Quasielastic Scattering from Polarized 3He

    Directory of Open Access Journals (Sweden)

    Sulkosky Vincent A.

    2016-01-01

    Full Text Available The 3He nucleus has become extremely important in the investigation of the neutron’s spin structure. When polarized, 3He acts as an effective polarized neutron target and hence facilitates our understanding of the neutron’s internal structure. However, to be used in this manner, our understanding of the internal structure of 3He is of extreme importance. As the precision of experiments has improved, the extraction of polarized neutron information from 3He leads to an ever larger share of the systematic uncertainty for these experiments. In these proceedings, I present a precise measurement of beam-target asymmetries in the He→3(e→ ,e′d${}^3\\overrightarrow {He} (\\vec e,e'd$ and He→3(e→,e′p${}^3\\overrightarrow {He} (\\vec e,e'p$ reactions. The former process is a uniquely sensitive probe of hadron dynamics in 3He and the structure of the underlying electromagnetic currents. The measurements have been performed around the quasi-elastic peak at Q2 = 0.25 (GeV/c2 and 0.35 (GeV/c2 for recoil momenta up to 270 MeV/c. The experimental apparatus, analysis and results were presented together with a comparison to state-of-the art Faddeev calculations.

  2. The development of 3He neutron detectors for applications in high level gamma-ray backgrounds

    International Nuclear Information System (INIS)

    To measure high-level-activity scrap and waste, it is necessary to use neutron detectors that are insensitive to the high gamma-ray background. We have developed a combination of 3He tubes and custom preamplifiers to provide the high efficiency associated with 3He detectors with good gamma-ray rejection. We have preamplifiers with short time constants in the signal processing to help separate the neutron signals from the slower risetime gamma signals. We have compared AMPTEK (A-111) preamplifiers with Precision Data Technology (PDT 110A) preamplifiers with experimental tests for gamma rejection and radiation damage. Hot cell radiation tests using a 4.5 Ci radium source were performed using 10B and 3He detectors to evaluate relative efficiency and the ability to separate neutrons and gamma rays. The AMPTEK A-111 and PDT-110A amplifiers were exposed to gamma doses between ∼0.1 R/h and 1500 R/h to observe where the gamma pileup would interfere with the neutron counting. The conclusion is that both amplifiers can operate in gamma fields up to ∼500 R/h with modest loss of neutron efficiency. This is valid for the case of only one 3He tube (30-cm active length) connected to a single amplifier. If an amplifier services multiple tubes or longer tubes, the gamma rejection will get worse. Studies are in progress to determine the lifetime of the amplifiers and 3He tubes in the high-radiation fields

  3. Results on Double-polarization Asymmetries in Quasielastic Scattering from Polarized 3He

    Energy Technology Data Exchange (ETDEWEB)

    Sulkosky, Vincent A. [Univ. of Virginia, Charlottesville, VA (United States); Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-03-01

    The 3He nucleus has become extremely important in the investigation of the neutron’s spin structure. When polarized, 3He acts as an effective polarized neutron target and hence facilitates our understanding of the neutron’s internal structure. However, to be used in this manner, our understanding of the internal structure of 3He is of extreme importance. As the precision of experiments has improved, the extraction of polarized neutron information from 3He leads to an ever larger share of the systematic uncertainty for these experiments. In these proceedings, I present a precise measurement of beam-target asymmetries in the and reactions. The former process is a uniquely sensitive probe of hadron dynamics in 3He and the structure of the underlying electromagnetic currents. The measurements have been performed around the quasi-elastic peak at Q2 = 0.25 (GeV/c)2 and 0.35 (GeV/c)2 for recoil momenta up to 270 MeV/c. The experimental apparatus, analysis and results were presented together with a comparison to state-of-the art Faddeev calculations.

  4. Longitudinal assessment of treatment effects on pulmonary ventilation using 1H/3He MRI multivariate templates

    Science.gov (United States)

    Tustison, Nicholas J.; Contrella, Benjamin; Altes, Talissa A.; Avants, Brian B.; de Lange, Eduard E.; Mugler, John P.

    2013-03-01

    The utitlity of pulmonary functional imaging techniques, such as hyperpolarized 3He MRI, has encouraged their inclusion in research studies for longitudinal assessment of disease progression and the study of treatment effects. We present methodology for performing voxelwise statistical analysis of ventilation maps derived from hyper­ polarized 3He MRI which incorporates multivariate template construction using simultaneous acquisition of IH and 3He images. Additional processing steps include intensity normalization, bias correction, 4-D longitudinal segmentation, and generation of expected ventilation maps prior to voxelwise regression analysis. Analysis is demonstrated on a cohort of eight individuals with diagnosed cystic fibrosis (CF) undergoing treatment imaged five times every two weeks with a prescribed treatment schedule.

  5. A Short History of the Theory and Experimental Discovery of Superfluidity in 3He

    Science.gov (United States)

    Brinkman, W. F.

    I discuss the development of the theory and experiments on superfluid 3He. After the discovery of superfluidity in 3He by Osheroff, Richardson and Lee, Phil Anderson quickly recruited Doug Osheroff to come to Bell Labs and set up a dilution fridge to continue his experiments. One of the mysteries at that time was how the high-temperature A-phase, which has a gapless excitation spectrum, could be stabilized relative to the fully gapped, lower temperature B-phase. I explain how Phil Anderson and I developed the spin fluctuation theory of the A-phase of superfluid 3He which accounted for its stability, leading to the Anderson-Brinkman-Morel (ABM) theory of the superfluid A-phase...

  6. Experimental study of the 56Ni(3He,d)57Cu reaction in inverse kinematics

    International Nuclear Information System (INIS)

    Measurements of (3He,d) reactions can provide information on the proton widths of states that play a role in astrophysically important (p,γ) reactions. We report on the first study of the (3He,d) reaction in inverse kinematics with a 56Ni (T1/2=6.1 d) ion beam. The Q-value resolution of ∼ keV achieved in this experiment was sufficient to separate the transitions populating the ground state and the 1/2--5/2- doublet at Ex∼1.1 MeV in 57Cu. Prospects for similar (3He,d) experiments with improved energy resolution are also discussed.

  7. The Effect Of Neutron Attenuation On Power Deposition In Nuclear Pumped 3He-Lasers

    Science.gov (United States)

    Çetin, Füsun

    2007-04-01

    Nuclear-pumped lasers (NPLs) are driven by the products of nuclear reactions and directly convert the nuclear energy to directed optical energy. Pumping gas lasers by nuclear reaction products has the advantage of depositing large energies per reaction. The need for high laser power output implies high operating pressure. In the case of volumetric excitation by 3He(n, p)3H reactions, however, operation at high pressure (more than a few atm) causes excessive neutron attenuation in the 3He gas. This fact adversely effects on energy deposition and, hence, laser output power and beam quality. Here, spatial and temporal variations of neutron flux inside a closed 3He -filled cylindrical laser tube have been numerically calculated for various tube radii and operating pressures by using a previously reported dynamic model for energy deposition. Calculations are made by using ITU TRIGA Mark II Reactor as the neutron source. The effects of neutron attenuation on power deposition are examined.

  8. Study of 68Zn, 70Zn and 74Ge using the (d,3He) reaction

    International Nuclear Information System (INIS)

    The 69Ga, 71Ga(d,3He)68Zn, 70Zn and 75As(d,3He)74Ge reactions have been studied at 26MeV with an overall resolution of 18-20keV using a split pole magnetic spectrometer. Spectroscopic factors have been extracted for 16 levels in 68Zn, 14 levels in 70Zn and 24 levels in 74Ge. The ratio R=sigma(02+)/sigma(0+g.s.) shows a singularity at N=40. The small value of R for 74Ge is consistent with a previously proposed description of the structure of the states involved which is based on a simple mixing of psub(3/2) and fsub(5/2) proton configurations. The results for the Ga(d,3He)Zn reactions are compared to a recent shell model calculation

  9. Modelling the effect of 3He in direct drive capsule implosions

    Science.gov (United States)

    Garbett, W. J.; Horsfield, C. J.; Herrmann, H. W.; Langenbrunner, J. R.; Cooley, J. H.; Wilson, D. C.; Evans, S. C.; Sedillo, T. J.; Rubery, M. S.; Drew, D.; Mack, J. M.; Young, C. S.; Kyrala, G. A.; Frenje, J.; Glebov, V. Yu

    2010-08-01

    D3He fuels are often used in ICF implosion experiments, either as a surrogate for DT to restrict the output neutron yield, or to produce protons for use in diagnosis of core conditions. Recent experiments have suggested that capsules filled with D3He do not behave as expected, but that both proton and neutron yields are anomalously degraded relative to the pure D2 case. We have performed direct drive implosion experiments using the Omega laser to examine the effect of 3He on DT-filled glass capsules. The use of DT fuel allows reaction history measurements to be obtained using the Gas Cherenkov diagnostic (GCD). It was hoped that the detailed information provided by GCD measurements would complement existing measurements to constrain modelling. We present recent modelling and analysis of the experiments using radiation-hydrocode simulations, and explore some of the hypotheses proposed to explain the results.

  10. Binding energy of one [sup 4]He impurity in liquid [sup 3]He

    Energy Technology Data Exchange (ETDEWEB)

    Boronat, J. (Universitat Politecnica de Catalunya, Barcelona (Spain)); Saavedra, F.A. de; Buendia, E. (Universidad de Granola (Spain)); Polls, A. (Universitat de Barcelona (Spain))

    1994-02-01

    A variational microscopic calculation of the binding energy of a [sup 4]He impurity ([mu][sub I]) in homogeneous liquid [sup 3]He at zero temperature is presented. Starting on an extended Jastrow-Slater wave function including three-body correlations, the expression for [mu][sub I] is derived and the appropriated FHNC formalism for this problem is reviewed. In the framework of the Average Correlation Approximation (ACA), it is proved that it is possible to obtain the chemical potential of the impurity only from liquid [sup 3]He magnitudes with a good accuracy. The results are consistent with both a recent experimental determination of [mu][sub I] at zero pressure and the non-solubility of [sup 4]He in [sup 3]He. However, numerical uncertainties preclude a firm conclusion about the latter property.

  11. Double-Cell Geometry for 129Xe/3He Co-Magnetometry

    Science.gov (United States)

    Ohtomo, Yuichi; Ichikawa, Yuichi; Sato, Tomoya; Sakamoto, Yu; Kojima, Shuichiro; Suzuki, Takahiro; Shirai, Hazuki; Chikamori, Masatoshi; Hikota, Eri; Miyatake, Hirokazu; Nanao, Tsubasa; Suzuki, Kunifumi; Tsuchiya, Masato; Inoue, Takeshi; Furukawa, Takeshi; Yoshimi, Akihiro; Bidinosti, Christopher P.; Ino, Takashi; Ueno, Hideki; Matsuo, Yukari; Fukuyama, Takeshi; Asahi, Koichiro

    Comagnetometers play a key role in EDM experiments. They allow one to quantify, and subsequently correct for, any long-term drifts of the external magnetic field. In order to improve the performance of the 3He comagnetometer for our 129Xe EDM measurements, we have decided to incorporate a double-cell geometry which enables us to suppress a frequency shift due to contact interaction with polarized Rb atoms. In this study, the production and relaxation of 3He spin polarization in the double cell were studied. As a result, the followings were achieved: a polarization of 1.04(8)%, a longitudinal spin relaxation time of 10.1(5) h, and a transverse relaxation time of 2,340 s. With these improvements, concurrent operation of the 129Xe and 3He masers has been realized, and EDM measurement will be started in near future using a cell designed based on the results of this study.

  12. Antisymmetry and channel coupling contributions to the absorption for $p + \\alpha /d + ^{3}He$

    CERN Document Server

    Cooper, S G

    1997-01-01

    To understand recently established empirical p + alpha potentials, RGM calculations followed by inversion are made to study contributions of the d + 3He reaction channels and deuteron distortion effects to the p + alpha potential. An equivalent study of the d + 3He potential is also presented. The contributions of exchange non-locality to the absorption are simulated by including an phenomenological imaginary potential in the RGM. These effects alone strongly influence the shape of the imaginary potentials for both p + alpha and d + 3He. The potentials local-equivalent to the fully antisymmetrised-coupled channels calculations have a significant parity-dependence in both real and imaginary components, which for p + alpha is qualitatively similar to that found empirically. The effects on the potentials of the further inclusion of deuteron distortion are also presented. The inclusion of a spin-orbit term in the RGM, adds additional terms to the phase-equivalent potential, most notably the comparatively large im...

  13. Bi-layer ^3He: a simple two dimensional heavy fermion system with quantum criticality

    Science.gov (United States)

    Saunders, John

    2008-03-01

    Two dimensional helium films provide simple model systems for the investigation of quantum phase transitions in two dimensions. Monolayer ^3He absorbed on graphite, with various pre-platings, behaves as a two dimensional Mott-Hubbard system, complete with a density driven ``metal-insulator'' transition [1, 2] into what appears to be a gapless spin-liquid. In two dimensions the corrections to the temperature dependence of the fluid heat capacity, beyond the term linear in T, are anomalous and attributed to quasi-1D scattering [3]. On the other hand, bi-layer ^3He films adsorbed on the surface of graphite show evidence of two-band heavy-fermion behavior and quantum criticality [4, 5]. The relevant control parameter is the total density of the ^3He film. The ^3He bilayer system can be driven toward a quantum critical point (QCP) at which the effective mass appears to diverge, the effective inter-band hybridization vanishes, and a local moment state appears. A theoretical model in terms of a ``Kondo breakdown selective Mott transition'' has recently been suggested [6]. * In collaboration with: A Casey, M Neumann, J Nyeki, B Cowan. [1] Evidence for a Mott-Hubbard Transition in a Two-Dimensional ^3He Fluid Monolayer, A. Casey, H. Patel, J. Ny'eki, B. P. Cowan, and J. Saunders Phys. Rev. Lett. 90, 115301 (2003) [2] D Tsuji et al. J. Low Temp. Phys. 134, 31 (2004) [3] A V Chubukov et al. Phys. Rev. B71, 205112 (2005) [4] Bilayer ^3He; a simple two dimensional heavy fermion system with quantum criticality, Michael Neumann, Jan Nyeki, Brian Cowan, John Saunders. Science 317, 1356 (2007) [5] Heavy fermions in the original Fermi liquid. Christopher A Hooley and Andrew P Mackenzie. Science 317, 1332 (2007) [6] C Pepin, Phys. Rev. Lett. 98, 206401 (2007) and A Benlagra and C Pepin, arXiv: 0709.0354

  14. Boron-coated straws as a replacement for 3He-based neutron detectors

    Science.gov (United States)

    Lacy, Jeffrey L.; Athanasiades, Athanasios; Sun, Liang; Martin, Christopher S.; Lyons, Tom D.; Foss, Michael A.; Haygood, Hal B.

    2011-10-01

    US and international government efforts to equip major seaports with large area neutron detectors, aimed to intercept the smuggling of nuclear materials, have precipitated a critical shortage of 3He gas. It is estimated that the annual demand of 3He for US security applications alone is more than the worldwide supply. This is strongly limiting the prospects of neutron science, safeguards, and other applications that rely heavily on 3He-based detectors. Clearly, alternate neutron detection technologies that can support large sensitive areas, and have low gamma sensitivity and low cost must be developed. We propose a low-cost technology based on long copper tubes (straws), coated on the inside with a thin layer of 10B-enriched boron carbide ( 10B 4C). In addition to the high abundance of boron on Earth and low cost of 10B enrichment, the boron-coated straw (BCS) detector offers distinct advantages over conventional 3He-based detectors, and alternate technologies such as 10BF 3 tubes and 10B-coated rigid tubes. These include better distribution inside moderator assemblies, many-times faster electronic signals, no pressurization, improved gamma-ray rejection, no toxic or flammable gases, and ease of serviceability. We present the performance of BCS detectors dispersed in a solid plastic moderator to address the need for portal monitoring. The design adopts the outer dimensions of currently deployed 3He-based monitors, but takes advantage of the small BCS diameter to achieve a more uniform distribution of neutron converter throughout the moderating material. We show that approximately 63 BCS detectors, each 205 cm long, distributed inside the moderator, can match or exceed the detection efficiency of typical monitors fitted with a 5 cm diameter 3He tube, 187 cm long, pressurized to 3 atm.

  15. First doubly polarised photoproduction on {sup 3}He at the photon beam of MAMI

    Energy Technology Data Exchange (ETDEWEB)

    Aguar Bartolome, Patricia

    2010-11-15

    A first experiment with a polarised {sup 3}He target was carried out in July 2009 at the MAMI accelerator in Mainz in a photon energy range between 200 MeV and 800 MeV. The aim of this measurement was to investigate the Gerasimov-Drell-Hearn sum rule on the neutron. The use of the data obtained with the polarised {sup 3}He target, compared to existing data on the deuteron, gives a complementary and more direct access to the neutron, due to the spin structure of the {sup 3}He. The measurement of the helicity dependence of the inclusive total photoabsorption cross section required a beam of tagged circularly polarised photons incident on the longitudinally polarised {sup 3}He target. The data were taken using the 4{pi} Crystal Ball photon spectrometer in combination with TAPS as a forward wall and complemented by a threshold Cherenkov detector used to on-line suppress the background from electromagnetic events. The development and preparation of the different components of the {sup 3}He experimental setup was an important part of this work and are described in detail in this thesis. The detector system and the analysis method were tested by the measurement of the unpolarised total inclusive photoabsorption cross section on liquid hydrogen. The results obtained are in good agreement with previous published data. Preliminary results of the unpolarised total photoabsorption cross section, as well as the helicity dependent photoabsorption cross section difference on {sup 3}He compared with several theoretical models will also be presented. (orig.)

  16. Neutron fluence determination at reactor filters by 3He proportional counters: Comparison of unfolding algorithms

    International Nuclear Information System (INIS)

    Multichannel pulse height measurements with a cylindrical 3He proportional counter obtained at a reactor filter of natural iron are taken to investigate the properties of three algorithms for neutron spectrum unfolding. For a systematic application of uncertainty propagation the covariance matrix of previously determined 3He response functions is evaluated. The calculated filter transmission function together with a covariance matrix estimated from cross-section uncertainties of the filter material is used as fluence pre-information. The results obtained from algorithms with and without pre-information differ in shape and uncertainties for single group fluence values, but there is sufficient agreement when evaluating integrals over neutron energy intervals

  17. Precision measurement of thermal neutron beam densities using a 3He proportional counter

    DEFF Research Database (Denmark)

    Als-Nielsen, Jens Aage; Bahnsen, A.; Brown, W.K.

    1967-01-01

    A new method, based on the 3He(n, p)T reaction, has been developed for the accurate determination of thermal neutron beam densities. Several comparisons were made with the conventional Au-foil activation method, and agreement was obtained between the two methods within an experimental uncertainty...... of ±0.4%. Fundamental advantages of the method include the 1ν dependence of the 3He(n, p)T cross section up to 1 keV, and the assurance of homogeneity even for very small macroscopic cross sections, because of the gaseous detector material. Although the method requires a relatively clean neutron beam...

  18. EXISTENCE AND REGULARITY OF SOLUTIONS TO MODEL FOR LIQUID MIXTURE OF 3HE-4HE

    Institute of Scientific and Technical Information of China (English)

    Luo Hong; Pu Zhilin

    2012-01-01

    Existence and regularity of solutions to model for liquid mixture of 3He-4He is considered in this paper.First,it is proved that this system possesses a unique global weak solution in H1(Ω,C × R) by using Galerkin method.Secondly,by using an iteration procedure,regularity estimates for the linear semigroups,it is proved that the model for liquid mixture of 3He-4He has a unique solution in Hk(Ω,C × R) for all k ≥ 1.

  19. SEOP polarized 3He Neutron Spin Filters for the JCNS user program

    Science.gov (United States)

    Babcock, Earl; Salhi, Zahir; Theisselmann, Tobias; Starostin, Denis; Schmeissner, Johann; Feoktystov, Artem; Mattauch, Stefan; Pistel, Patrick; Radulescu, Aurel; Ioffe, Alexander

    2016-04-01

    Over the past several years the JCNS has been developing in-house applications for neutron polarization analysis (PA). These methods include PA for separation of incoherent from coherent scattering in soft matter studies (SANS), and online polarization for analysis for neutron reflectometry, SANS, GISANS and eventually spectroscopy. This paper will present an overview of the user activities at the JCNS at the MLZ and gives an overview of the polarization 3He methods and devices used. Additionally we will summarise current projects which will further support the user activities using polarised 3He spin filters.

  20. Precision Measurement of the n-3He Incoherent Scattering Length Using Neutron Interferometry

    OpenAIRE

    Huber, M. G.; Arif, M.; Black, T. C.; W.C. Chen; Gentile, T. R.; Hussey, D. S.; Pushin, D.; Wietfeldt, F. E.; Yang, L

    2008-01-01

    We report the first measurement of the low-energy neutron-$^3$He incoherent scattering length using neutron interferometry: $b_i' = (-2.512\\pm 0.012{statistical}\\pm0.014{systematic})$ fm. This is in good agreement with a recent calculation using the AV18+3N potential. The neutron-$^3$He scattering lengths are important for testing and developing nuclear potential models that include three nucleon forces, effective field theories for few-body nuclear systems, and neutron scattering measurement...

  1. Benchmark calculation of p-3H and n-3He scattering

    CERN Document Server

    Viviani, M; Lazauskas, R; Fonseca, A C; Kievsky, A; Marcucci, L E

    2016-01-01

    p-3H and n-3He scattering in the energy range above the n-3He but below the d-d thresholds is studied by solving the 4-nucleon problem with a realistic nucleon-nucleon interaction. Three different methods -- Alt, Grassberger and Sandhas, Hyperspherical Harmonics, and Faddeev-Yakubovsky -- have been employed and their results for both elastic and charge-exchange processes are compared. We observe a good agreement between the three different methods, thus the obtained results may serve as a benchmark. A comparison with the available experimental data is also reported and discussed.

  2. High-efficiency microstructured semiconductor neutron detectors for direct {sup 3}He replacement

    Energy Technology Data Exchange (ETDEWEB)

    Fronk, R.G., E-mail: rfronk@ksu.edu [S.M.A.R.T. Laboratory, Department of Mechanical and Nuclear Engineering, Kansas State University, Manhattan, KS 66506 (United States); Bellinger, S.L.; Henson, L.C. [S.M.A.R.T. Laboratory, Department of Mechanical and Nuclear Engineering, Kansas State University, Manhattan, KS 66506 (United States); Huddleston, D.E. [Electronics Design Laboratory, Kansas State University, Manhattan, KS 66506 (United States); Ochs, T.R. [S.M.A.R.T. Laboratory, Department of Mechanical and Nuclear Engineering, Kansas State University, Manhattan, KS 66506 (United States); Sobering, T.J. [Electronics Design Laboratory, Kansas State University, Manhattan, KS 66506 (United States); McGregor, D.S. [S.M.A.R.T. Laboratory, Department of Mechanical and Nuclear Engineering, Kansas State University, Manhattan, KS 66506 (United States)

    2015-04-11

    High-efficiency Microstructured Semiconductor Neutron Detectors (MSNDs) have been tiled and arranged in a cylindrical form factor in order to serve as a direct replacement to aging and increasingly expensive {sup 3}He gas-filled proportional neutron detectors. Two 6-in long by 2-in diameter cylinders were constructed and populated with MSNDs which were then directly compared to a 4 atm Reuter Stokes {sup 3}He detector of the same dimensions. The Generation 1 MSND-based {sup 3}Helium-Replacement (HeRep Mk I) device contained sixty-four 1-cm{sup 2} active-area MSNDs, each with an intrinsic neutron detection efficiency of approximately 7%. A Generation 2 device (the HeRep Mk II) was populated with thirty 4-cm{sup 2} active-area MSNDs, with an intrinsic thermal neutron detection efficiency of approximately 30%. The MSNDs of each HeRep were integrated to count as a single device. The {sup 3}He proportional counter and the HeRep devices were tested while encased in a cylinder of high-density polyethylene measuring a total of 6-in by 9-in. The {sup 3}He counter and the HeRep Mk II were each placed 1 m from a 54-ng {sup 252}Cf source and tested for efficiency. The {sup 3}He proportional counter had a net count rate of 17.13±0.10 cps at 1 m. The HeRep Mk II device had a net count rate of 17.60±0.10 cps, amounting to 102.71±2.65% of the {sup 3}He gas counter while inside of the moderator. Outside of moderator, the {sup 3}He tube had a count rate of 3.35±0.05 cps and the HeRep Mk II device reported 3.19±05, amounting to 95.15±9.04% of the {sup 3}He neutron detector.

  3. Liquid crystal polarimetry for metastability exchange optical pumping of {sup 3}He

    Energy Technology Data Exchange (ETDEWEB)

    Maxwell, J.D., E-mail: jdmax@mit.edu; Epstein, C.S.; Milner, R.G.

    2014-11-11

    We detail the design and operation of a compact, discharge light polarimeter for metastability exchange optical pumping of {sup 3}He gas near 1 torr under a low magnetic field. The nuclear polarization of {sup 3}He can be discerned from its electron polarization, measured via the circular polarization of 668 nm discharge light from an RF excitation. This apparatus measures the circular polarization of this very dim discharge light using a nematic liquid crystal wave retarder (LCR) and a high-gain, transimpedance amplified Si photodiode. We outline corrections required in such a measurement and discuss contributions to its systematic error.

  4. Decoupling between first sound and second sound in $^3$He - superfluid $^4$He mixtures

    OpenAIRE

    Riekki, T. S.; Manninen, M. S.; Tuoriniemi, J. T.

    2016-01-01

    Bulk superfluid helium supports two sound modes: first sound is an ordinary pressure wave, while second sound is a temperature wave, unique to inviscid superfluid systems. These sound modes do not usually exist independently, but rather variations in pressure are accompanied by variations in temperature, and vice versa. We studied the coupling between first and second sound in dilute $^3$He - superfluid $^4$He mixtures, between 1.6 K and 2.2 K, at $^3$He concentrations ranging from 0 to 11 %,...

  5. The Gas Motion Due To Non-Uniform Heating By 3He(n,p)3H Reactions In The Nuclear-Pumped3He -Lasers

    Science.gov (United States)

    Çetin, Füsun

    2007-04-01

    In the nuclear pumped-lasers, the passage of these energetic charged particles through gas results in a non-uniform volumetric energy deposition. This spatial non-uniformity induces a gas motion, which results in density and hence refractive index gradients that affects the laser's optical behaviour. The motion of 3He gas in a closed cavity is studied when it experiences transient and spatially non-uniform volumetric heating caused by the passage of 3He(n,p)3H reaction products. Gas motion is described by the radial velocity field of gas flow. Spatial and temporal variations of radial gas velocity are calculated for various tube parameters by using a dynamic energy deposition model. In the calculations, it is assumed that the laser tube is irradiated with neutrons from the pulse at a peak power of 1200 MW corresponding to a maximum thermal neutron flux of 8×1016 n / cm2sn in the central channel of ITU TRIGA Mark II Reactor. Results are examined.

  6. Study of response of {sup 3}He detectors to monoenergetic neutrons; Etude des reponses des detecteurs a {sup 3}He par des neutrons monoenergetiques

    Energy Technology Data Exchange (ETDEWEB)

    Abanades, A. [European Organization for Nuclear Research, Geneva (CERN); Andriamonje, S.; Arnould, H.; Barreau, G.; Bercion, M. [Centre d`Etudes Nucleaires, Bordeaux-1 Univ., 33 Gradignan (France); Casagrande, F.; Cennini, P. [European Organization for Nuclear Research, Geneva (CERN); Del Moral, R. [Centre d`Etudes Nucleaires, Bordeaux-1 Univ., 33 Gradignan (France); Gonzales, E. [European Organization for Nuclear Research, Geneva (CERN); Lacoste, V.; Pdemay, G.; Pravikoff, M.S. [Centre d`Etudes Nucleaires, Bordeaux-1 Univ., 33 Gradignan (France); TARC Collaboration under leadership of C. Rubbia

    1997-06-01

    In the search of a hybrid system (the coupling of the particle accelerator to an under-critical reactor) for radioactive waste transmutation the TARC (Transmutation by Adiabatic Resonance Crossing) program has been developed. Due to experimental limitations, the time-energy relation at higher neutron energies, particularly, around 2 MeV, which is an important domain for TARC, cannot be applied. Consequently the responses of the {sup 3}He ionization neutron detector developed for TARC experiment have been studied using a fast monoenergetic neutron source. The neutrons were produced by the interaction of the proton delivered by Van de Graaff accelerator of CENBG. The originality of the detector consists in its structure of three series of electric conductors which are mounted around the anode: a grid ensuring the detector proportionality, a cylindrical suit of alternating positive voltage and grounded wires aiming at eliminating the radial end effects, serving as veto and two cylinders serving as end plugs to eliminate the perpendicular end effects. Examples of anode spectra conditioned (in anticoincidence) by the mentioned vetoes are given. One can see the contribution of the elastic scattering from H and {sup 3}He. By collimating the neutron beam through a borated polyethylene system it was possible to obtain a mapping of the detector allowing the study of its response as a function of the irradiated zones (anode and grid) 2 refs. This paper is related to TRN FR9810178

  7. 3He(α,γ7Be cross section measured using complementary techniques

    Directory of Open Access Journals (Sweden)

    Carmona-Gallardo M.

    2014-03-01

    Full Text Available The astrophysical S-factor for the 3He(α,γ7Be reaction plays an important role in the Solar Standard Model and in the Big Bang Nucleosynthesis scenario. The advances from two recent experiments performed using complementary techniques at center of mass (C.M. energies between 1 and 3 MeV are discussed.

  8. Energy spectra of 3He-rich solar energetic particles associated with coronal waves

    CERN Document Server

    Bucik, R; Mason, G M; Wiedenbeck, M E

    2016-01-01

    In addition to their anomalous abundances, 3He-rich solar energetic particles (SEPs) show puzzling energy spectral shapes varying from rounded forms to power laws where the later are characteristics of shock acceleration. Solar sources of these particles have been often associated with jets and narrow CMEs, which are the signatures of magnetic reconnection involving open field. Recent reports on new associations with large-scale EUV waves bring new insights on acceleration and transport of 3He-rich SEPs in the corona. We examined energy spectra for 32 3He-rich SEP events observed by ACE at L1 near solar minimum in 2007-2010 and compared the spectral shapes with solar flare signatures obtained from STEREO EUV images. We found the events with jets or brightenings tend to be associated with rounded spectra and the events with coronal waves with power laws. This suggests that coronal waves may be related to the unknown second stage mechanism commonly used to interpret spectral forms of 3He-rich SEPs.

  9. Association of 3He-rich solar energetic particles with large-scale coronal waves

    Science.gov (United States)

    Bucik, Radoslav; Innes, Davina; Guo, Lijia; Mason, Glenn M.; Wiedenbeck, Mark

    2016-07-01

    Impulsive or 3He-rich solar energetic particle (SEP) events have been typically associated with jets or small EUV brightenings. We identify 30 impulsive SEP events from ACE at L1 during the solar minimum period 2007-2010 and examine their solar sources with high resolution STEREO-A EUV images. At beginning of 2007, STEREO-A was near the Earth while at the end of the investigated period, when there were more events, STEREO-A was leading the Earth by 90°. Thus STEREO-A provided a better (more direct) view on 3He-rich flares generally located on the western Sun's hemisphere. Surprisingly, we find that about half of the events are associated with large-scale EUV coronal waves. This finding provides new insights on acceleration and transport of 3He-rich SEPs in solar corona. It is believed that elemental and isotopic fractionation in impulsive SEP events is caused by more localized processes operating in the flare sites. The EUV waves have been reported in gradual SEP events in association with fast coronal mass ejections. To examine their role on 3He-rich SEPs production the energy spectra and relative abundances are discussed. R. Bucik is supported by the Deutsche Forschungsgemeinschaft under grant BU 3115/2-1.

  10. The reaction mechanism of the (3HE,T) reaction and applications to nuclear structure

    NARCIS (Netherlands)

    1986-01-01

    In this thesis we present a study on the reaction meachanism of the (3He,t) reaction at 70-80 MeV bombarding energy and on structures of the residual nuclei excited in this reaction: 24-Al, 26-Al, 28-P, 32-Cl, 40-Sc, 42-Sc and 58-Cu... Zie: Summary

  11. Study of the deeply bound hole states by the (3He,α) reaction

    International Nuclear Information System (INIS)

    The (3He,α) reactions at 110 - 120 MeV on even tin isotopes revealed the presence of the new (1g)-1 state at Ex = 6 -- 7 MeV with a spectroscopic factor comparable to the known (1g sub(9/2))-1 deeply bound hole state. (author)

  12. Observations of EUV Waves in 3He-Rich Solar Energetic Particle Events

    CERN Document Server

    Bucik, R; Guo, L; Mason, G M; Wiedenbeck, M E

    2015-01-01

    Small 3He-rich solar energetic particle (SEP) events with their anomalous abundances, markedly different from solar system, provide evidence for a unique acceleration mechanism that operates routinely near solar active regions. Although the events are sometimes accompanied by coronal mass ejections (CMEs) it is believed that mass and isotopic fractionation is produced directly in the flare sites on the Sun. We report on a large-scale extreme ultraviolet (EUV) coronal wave observed in association with 3He-rich SEP events. In the two examples discussed, the observed waves were triggered by minor flares and appeared concurrently with EUV jets and type III radio bursts but without CMEs. The energy spectra from one event are consistent with so-called class-1 (characterized by power laws) while the other with class-2 (characterized by rounded 3He and Fe spectra) 3He-rich SEP events, suggesting different acceleration mechanisms in the two. The observation of EUV waves suggests that large-scale disturbances, in addit...

  13. The effects of nuclear structure on generalized parton distributions of 3He

    OpenAIRE

    Scopetta, S.

    2004-01-01

    The effect of the nuclear medium on generalized parton distributions (GPDs) is studied for the 3He nucleus, through a realistic microscopic analysis. In Impulse Approximation, Fermi motion and binding effects, evaluated by modern potentials, are found to be larger than in the forward case and very sensitive to the details of nuclear structure at short distances.

  14. Association of 3He-Rich Solar Energetic Particles with Large-Scale Coronal Waves

    CERN Document Server

    Bucik, Radoslav; Mason, Glenn M; Wiedenbeck, Mark E

    2016-01-01

    Small 3He-rich solar energetic particle (SEP) events have been commonly associated with extreme-ultraviolet (EUV) jets and narrow coronal mass ejections (CMEs) which are believed to be the signatures of magnetic reconnection involving field lines open to interplanetary space. The elemental and isotopic fractionation in these events are thought to be caused by processes confined to the flare sites. In this study we identify 32 3He-rich SEP events observed by the Advanced Composition Explorer near the Earth during the solar minimum period 2007-2010 and examine their solar sources with the high resolution Solar Terrestrial Relations Observatory (STEREO) EUV images. Leading the Earth, STEREO-A provided for the first time a direct view on 3He-rich flares, which are generally located on the Sun's western hemisphere. Surprisingly, we find that about half of the 3He-rich SEP events in this survey are associated with large-scale EUV coronal waves. An examination of the wave front propagation, the source-flare distribu...

  15. Nuclear effects and neutron structure in deeply virtual Compton scattering off 3He

    CERN Document Server

    Rinaldi, Matteo

    2014-01-01

    The study of nuclear generalized parton distributions (GPDs) could be a crucial achievement of hadronic physics since they open new ways to obtain new information on the structure of bound nucleons, in particular, to access the neutron GPDs. Here, the results of calculations of 3He GPDs in Impulse Approximation are presented. The calculation of the sum of GPDs H + E, and "tilde H", with the correct limits, will be shown. These quantities, at low momentum transfer, are largely dominated by the neutron contribution so that 3He is an ideal target for these kind of studies. Nevertheless the extraction of neutron information from future 3He data could be non trivial. A procedure, which takes into account nuclear effects encoded in IA, is presented. The calculation of H,E and "tilde H" allows also to evaluate the cross section asymmetries for deeply virtual compton scattering at Jefferson Lab kinematics. Thanks to these observations, DVCS off 3He could be an ideal process to access the neutron information in the ne...

  16. Neutron scattering from liquid {sup 3}He at large momentum transfers

    Energy Technology Data Exchange (ETDEWEB)

    Azuah, R.T. [Keele Univ. (United Kingdom). Dept. of Physics]|[Department of Physics and Astronomy, University of Delaware, Newark, Delaware 19716 (United States); Stirling, W.G. [Keele Univ. (United Kingdom). Dept. of Physics; Guckelsberger, K. [Physikalisch-Technische Bundesanstalt, Bundesallee 100, Postfach 3345, 38116 Braunschweig (Germany); Scherm, R. [Physikalisch-Technische Bundesanstalt, Bundesallee 100, Postfach 3345, 38116 Braunschweig (Germany)]|[Institut Laue-Langevin, BP 156X, F-38042 Grenoble (France); Glyde, H.R. [Department of Physics and Astronomy, University of Delaware, Newark, Delaware 19716 (United States); Bennington, S.M. [Rutherford Appleton Laboratory, Chilton, Didcot, Oxon, OX11 0QX (United Kingdom); Taylor, A.D. [Rutherford Appleton Laboratory, Chilton, Didcot, Oxon, OX11 0QX (United Kingdom)

    1995-08-01

    Neutron inelastic scattering measurements have been made on liquid {sup 3}He at 1.4 K for wave vectors between 9 and 20 A{sup -1}. The peak positions and widths are extracted and the mean kinetic energy determined. A new (theoretical) moment technique is used to investigate the momentum distribution and final-state effects. (orig.).

  17. sup 3 He neutron polarising filters -- theoretical comparison with supermirrors and Heusler alloy polarisers

    CERN Document Server

    Cussen, L D; Hicks, T J

    2000-01-01

    There is currently intense interest in the development of gaseous sup 3 He neutron polarising transmission filters. The key areas of development are increasing the currently achievable levels of nuclear spin polarisation, pi, within the sup 3 He gas and improving the reliability of the devices. Recent work has identified 'quality factors' which can be used to determine the optimum thickness of such filters under various experimental conditions. The best achievable quality factor for a sup 3 He polariser with a given pi is determined. It is demonstrated that the optimum filter thickness depends only weakly on pi and is always approximately given by the dimensionless expression rho sigma lambda t=3.4 where rho is the density of sup 3 He atoms in the filter, sigma is the absorption cross section at a wavelength of 1 A, lambda is the neutron wavelength in A and t is the filter thickness. Quality factors are calculated for existing types of neutron polariser (supermirrors and Heusler alloy monochromators) as a fun...

  18. {sup 3}He neutron polarising filters -- theoretical comparison with supermirrors and Heusler alloy polarisers

    Energy Technology Data Exchange (ETDEWEB)

    Cussen, L.D. E-mail: leocussen@vut.edu.au; Goossens, D.J.; Hicks, T.J

    2000-02-01

    There is currently intense interest in the development of gaseous {sup 3}He neutron polarising transmission filters. The key areas of development are increasing the currently achievable levels of nuclear spin polarisation, {pi}, within the {sup 3}He gas and improving the reliability of the devices. Recent work has identified 'quality factors' which can be used to determine the optimum thickness of such filters under various experimental conditions. The best achievable quality factor for a {sup 3}He polariser with a given {pi} is determined. It is demonstrated that the optimum filter thickness depends only weakly on {pi} and is always approximately given by the dimensionless expression {rho}{sigma}{lambda}t=3.4 where {rho} is the density of {sup 3}He atoms in the filter, {sigma} is the absorption cross section at a wavelength of 1 A, {lambda} is the neutron wavelength in A and t is the filter thickness. Quality factors are calculated for existing types of neutron polariser (supermirrors and Heusler alloy monochromators) as a function of instrumental parameters. These results are used to determine the 'break even' point for the new polarisers - the {pi} needed for the new polarisers to outperform existing types of polarisers. A quantitative discussion of regimes of usefulness of the different polariser types for all common instrument types is presented.

  19. The polarized 3He(d,p)4He reaction at Elab = 270Mev

    International Nuclear Information System (INIS)

    The 3He(d, p)4He reaction is one of the important processes in the primordial nuclearsynthesis of the universe. Furthermore, the reaction of a polarized 3He target with a polarized deuterium beam at E1ab = 270MeV would be an ambitious experiment in which a constraint on the deuteron D-state probability could be measured directly. Moreover, the reaction is interesting as an example of how to treat the five-body problem from a Faddeev theory point of view. Our approach involves coupled Faddeev equations for the 3He-p-n and d-d-p systems. Using two Faddeev equations, we obtained the scattering amplitudes 'Xhpn' and 'Xddp' for both the 3He-p-n and the d-d-p systems. Xhpn and Xddp were combined with each other by a proper normalization method. Finally, the differential cross section, the tensor analysing power, Ayy and Axx, the spin correlation coefficient, Cyy and Cxx, and the polarization correlation coefficient C// were investigated. We found that the amplitude Xhpn contributes mainly to the forward region of the differential cross section while Xddp contributes mainly to the backward region. Even for this calculation, the observables are smaller than the theoretical values at forward scattering angles. (author)

  20. Experimental Research of the Radiative Capture of Thermal Neutrons in $^{3}$He

    CERN Document Server

    Bystritsky, V M; Enik, T L; Filipowicz, M; Gerasimov, V V; Grebenyuk, V M; Kobzev, A P; Kublikov, R V; Nesvizhevsky, V V; Parzhitskii, S S; Pavlov, V N; Popov, N P; Salamatin, A V; Shvetsov, V N; Slepnev, V M; Strelkov, A V; Wozniak, J; Zamyatin, N I

    2006-01-01

    A project of an experiment on measurement of the cross sections of radiative thermal neutron capture by $^{3}$He nuclei with production of one and two $\\gamma $-quanta ($n_{\\rm th}+^{3}$He $\\to \\alpha + \\gamma $(2$\\gamma $)) is presented. The interest in studying the processes is dictated by the following factors: a possibility of obtaining information on parameters of the nucleon $N$-$N$ potential and structure of exchange meson currents; a possibility of verifying the model of the mechanism for nucleon capture by the nucleus $^{3}$He in the low-energy region; necessity to solve some questions existing in astrophysics. The experiment is planned to be carried out on the PF1B beam of ILL reactor (Grenoble). The target is a hollow cylinder of pure aluminium ($\\varnothing$140$\\times $80~mm) filled with $^{3}$He and $^{4}$He (background experiment) at the pressure 2~atm. Registration of the $\\gamma $-quanta is carried out by four BGO crystal ($\\varnothing$100$\\times $70~mm) detectors. According to the calculation...

  1. The effects of nuclear structure on generalized parton distributions of 3He

    CERN Document Server

    Scopetta, S

    2005-01-01

    The effect of the nuclear medium on generalized parton distributions (GPDs) is studied for the 3He nucleus, through a realistic microscopic analysis. In Impulse Approximation, Fermi motion and binding effects, evaluated by modern potentials, are found to be larger than in the forward case and very sensitive to the details of nuclear structure at short distances.

  2. Connection between the 3HE-enrichment and spectral index of solar energetic particles

    International Nuclear Information System (INIS)

    A model is presented which explains the observed tendency of events with large He-3/He-4 ratios to have steeper spectra. In this model preferential injection of He-3, acceleration by Alfven waves and Coulomb deceleration of ions are considered simultaneously. The observed tendency may be obtained as a result of competition between injection and acceleration processes

  3. On temperature variations during 3He Polarization experiments in Pomeranchuk cells

    DEFF Research Database (Denmark)

    Geng, Q.; Rasmussen, Finn Berg

    1984-01-01

    Simple model calculations have been performed in relation to temperature changes in decompression experiments with Pomeranchuk cells, aiming at the production of spin polarized liquid **3He. Comparison with reported experiments indicates that thermal contact with the surroundings is too strong...

  4. Precision measurement of thermal neutron beam densities using a 3He proportional counter

    DEFF Research Database (Denmark)

    Als-Nielsen, Jens Aage; Bahnsen, A.; Brown, W.K.

    1967-01-01

    of ±0.4%. Fundamental advantages of the method include the 1ν dependence of the 3He(n, p)T cross section up to 1 keV, and the assurance of homogeneity even for very small macroscopic cross sections, because of the gaseous detector material. Although the method requires a relatively clean neutron beam...

  5. Possibility of Establishing D-3He Fusion Reactor Using Spherical Tokamaks

    Institute of Scientific and Technical Information of China (English)

    石秉仁

    2004-01-01

    Based on the recent progress in the spherical torus approach (ST), it is meaningful to revisit the possibility of establishing D-3He fusion reactor using both the ST and the tokamak scaling. Fundamental requirements then are obtained and some important issues are discussed. The wall reflection of the synchrotron radiation is very important for a good reactor merit.

  6. Moisture distribution measurements in adhesive-bonded composites using the D (3He,p)4 He reaction

    International Nuclear Information System (INIS)

    Adhesive bonding of composite materials for many aircraft components offers a distinct advantage in weight and cost reduction compared to similar structures that have been joined by riveting. However, the long term performance of adhesive-bonded components depends on the degree and rate of moisture absorption by the adhesive in the service environment. To investigate the rate and the mechanism of water transport in adhesive-bonded composite materials, a nuclear reaction analysis method based on the D(3He,p)4He reaction is used to measure the moisture distributions. Samples of graphite/epoxy composite materials were bonded with an epoxy adhesive and isothermally conditioned in a controlled D2O environment at 70% relative humidity and 770C for various exposure times. The moisture profiles were measured along the adhesive (adhesive scan) as well as through the thickness of the bonded joint (transverse scan). The dimensions of the probing beam were 125 μm x 125 μm for the adhesive scan and 25 μ x 200 μm for the transverse scan. Absolute deuterium concentrations were determined by comparison of the proton yield from the composite/adhesive to that from reference standards. Calculations from diffusion models of water transport based on parameters determined from bulk measurement techniques are compared to the measured profile and the agreement indicates that classical Fickian diffusion describes the transport of moisture in these materials

  7. Study of the pd(dp) -> 3He pi pi reactions close to threshold

    CERN Document Server

    Bellemann, F; Bisplinghoff, J; Bohlscheid, G; Ernst, J; Henrich, C; Hinterberger, F; Ibald, R; Jahn, R; Joosten, R; Kilian, K; Kozela, A; Machner, H; Magiera, A; Munkel, J; von Neumann-Cosel, P; von Rossen, P; Schnitker, H; Scho, K; Smyrski, J; Toelle, R; Wilkin, C

    2016-01-01

    New experimental data on the pd -> 3He pi+ pi- reaction obtained with the COSY-MOMO detector below the three-pion threshold are presented. The reaction was also studied in inverse kinematics with a deuteron beam and the higher counting rates achieved were especially important at low excess energies. The comparison of these data with inclusive pd -> 3He+X rates allowed estimates also to be made of pi0 pi0 production. The results confirm our earlier findings that close to threshold there is no enhancement at low excitation energies in the pi+ pi- system, where the data seem largely suppressed compared to phase space. Possible explanations for this behavior, such as strong p- waves in the pi+pi- -system or the influence of two-step processes, are explored.

  8. Probing Bogoliubov Quasiparticles in Superfluid ^3He with a `Vibrating-Wire Like' MEMS Device

    Science.gov (United States)

    Defoort, M.; Dufresnes, S.; Ahlstrom, S. L.; Bradley, D. I.; Haley, R. P.; Guénault, A. M.; Guise, E. A.; Pickett, G. R.; Poole, M.; Woods, A. J.; Tsepelin, V.; Fisher, S. N.; Godfrin, H.; Collin, E.

    2016-05-01

    We have measured the interaction between superfluid ^3He-B and a micro-machined goalpost-shaped device at temperatures below 0.2 T_c. The measured damping follows well the theory developed for vibrating wires, in which the Andreev reflection of quasiparticles in the flow field around the moving structure leads to a nonlinear frictional force. At low velocities, the damping force is proportional to velocity, while it tends to saturate for larger excitations. Above a velocity of 2.6 mm s^{-1}, the damping abruptly increases, which is interpreted in terms of Cooper-pair breaking. Interestingly, this critical velocity is significantly lower than that reported with other mechanical probes immersed in superfluid ^3He. Furthermore, we report on a nonlinear resonance shape for large motion amplitudes that we interpret as an inertial effect due to quasiparticle friction, but other mechanisms could possibly be invoked as well.

  9. High-3He plume origin and temporal-spatial evolution of the Siberian flood basalts

    Science.gov (United States)

    Basu, A.R.; Poreda, R.J.; Renne, P.R.; Teichmann, F.; Vasiliev, Y.R.; Sobolev, N.V.; Turrin, B.D.

    1995-01-01

    An olivine nephelinite from the lower part of a thick alkalic ultrabasic and mafic sequence of volcanic rocks of the northeastern part of the Siberian flood basalt province (SFBP) yielded a 40ArX39Ar plateau age of 253.3 ?? 2.6 million years, distinctly older than the main tholeiitic pulse of the SFBP at 250.0 million years. Olivine phenocrysts of this rock showed 3He/4He ratios up to 12.7 times the atmospheric ratio; these values suggest a lower mantle plume origin. The neodymium and strontium isotopes, rare earth element concentration patterns, and cerium/lead ratios of the associated rocks were also consistent with their derivation from a near-cnondritic, primitive plume. Geochemical data from the 250-million-year-old volcanic rocks higher up in the sequence indicate interaction of this high-3He SFBP plume with a suboceanic-type upper mantle beneath Siberia.

  10. JLab Measurements of the 3He Form Factors at Large Momentum Transfers

    CERN Document Server

    Camsonne, A; Olson, M; Acha, A; Allada, K; Anderson, B D; Arrington, J; Baldwin, A; Chen, J -P; Choi, S; Chudakov, E; Cisbani, E; Craver, B; Decowski, P; Dutta, C; Folts, E; Frullani, S; Garibaldi, F; Gilman, R; Gomez, J; Hahn, B; Hansen, J -O; Higinbotham, D W; Holmstrom, T; Huang, J; Iodice, M; Jiang, X; Kelleher, A; Khrosinkova, E; Kievsky, A; Kuchina, E; Kumbartzki, G; Lee, B; LeRose, J J; Lindgren, R A; Lott, G; Lu, H; Marcucci, L E; Margaziotis, D J; Markowitz, P; Marrone, S; Meekins, D; Meziani, Z -E; Michaels, R; Moffit, B; Norum, B; Petratos, G G; Puckett, A; Qian, X; Rondon, O; Saha, A; Sawatzky, B; Segal, J; Shabestari, M; Shahinyan, A; Solvignon, P; Sparveris, N; Subedi, R R; Suleiman, R; Sulkosky, V; Urciuoli, G M; Viviani, M; Wang, Y; Wojtsekhowski, B B; Yan, X; Yao, H; Zhang, W -M; Zheng, X; Zhu, L

    2016-01-01

    The charge and magnetic form factors, FC and FM, of 3He have been extracted in the kinematic range 25 fm-2 < Q2 < 61 fm-2 from elastic electron scattering by detecting 3He recoil nuclei and electrons in coincidence with the High Resolution Spectrometers of the Hall A Facility at Jefferson Lab. The measurements are indicative of a second diffraction minimum for the magnetic form factor, which was predicted in the Q2 range of this experiment, and of a continuing diffractive structure for the charge form factor. The data are in qualitative agreement with theoretical calculations based on realistic interactions and accurate methods to solve the three-body nuclear problem.

  11. Constraining short-range spin-dependent forces with polarized $^3$He

    CERN Document Server

    Guigue, Mathieu; Petukhov, Alexander K; Pignol, Guillaume

    2015-01-01

    We have searched for a short-range spin-dependent interaction using the spin relaxation of hyperpolarized $^3$He. Such a new interaction would be mediated by a hypothetical light scalar boson with \\CP-violating couplings to the neutron. The walls of the $^3$He cell would generate a pseudomagnetic field and induce an extra depolarization channel. We did not see any anomalous spin relaxation and we report the limit for interaction ranges $\\lambda$ between $1$ and $100~\\rm{\\mu m}$: $g_sg_p \\lambda ^2 \\leq 2.6\\times 10^{-28}~\\mathrm{m^2}\\, ( 95~\\%\\, \\mathrm{C.L.})$, where $g_s$($g_p$) are the (pseudo)scalar coupling constant, improving the previous best limit by 1 order of magnitude.

  12. Neutron scattering from liquid {sup 3}He at intermediate to large wavevectors

    Energy Technology Data Exchange (ETDEWEB)

    Azuah, R.T.; Stirling, W.G. [Keele Univ. (United Kingdom); Guckelsberger, K. [PTB, Braunschweig (Germany)] [and others

    1995-12-01

    Neutron inelastic scattering experiments have been performed on liquid {sup 3}He at saturated vapour pressure and T = 1.4 K covering a wide range of energy and momentum transfers (9 {le} Q {le} 20 {angstrom}{sup -1}). Allowing for the very strong {sup 3}He neutron absorption, the data is of excellent quality and it has been analysed to extract information on the scattering function widths, peak positions and single particle kinetic energies. It is found that there are no width oscillations with momentum transfer and that the average atomic kinetic energy is approximately 20% lower than theoretical predictions, in agreement with previous neutron scattering results. A new method of analysis aimed at extracting both the atomic momentum distribution and final state effects is also presented and the results discussed in the light of current theory.

  13. Introduction to the vortex sheet of superfluid 3He-A

    International Nuclear Information System (INIS)

    It is well known that superfluids respond to rotation by forming vortex lines. It has been recently discovered that a different type of state consisting of a vortex sheet, instead of lines, can be created in the A phase of superfluid 3He. This paper presents an introduction to the vortex sheet. We first discuss 4He, where a vortex sheet is unstable. The way to realize a stable sheet in 3He-A is called a vortex soliton. It consists of a topologically stable domain wall to which nonsingular vorticity is bound. The vortex soliton has been observed by nuclear magnetic resonance, and its most prominent experimental properties are explained. The macroscopic shape of the sheet and the superfluid flow in a rotating container are discussed. (orig.)

  14. Spin-Correlation Coefficients and Phase-Shift Analysis for p+$^3$He Elastic Scattering

    CERN Document Server

    Daniels, T V; Cesaratto, J M; Clegg, T B; Couture, A H; Karwowski, H J; Katabuchi, T

    2010-01-01

    Angular Distributions for the target spin-dependent observables A$_{0y}$, A$_{xx}$, and A$_{yy}$ have been measured using polarized proton beams at several energies between 2 and 6 MeV and a spin-exchange optical pumping polarized $^3$He target. These measurements have been included in a global phase-shift analysis following that of George and Knutson, who reported two best-fit phase-shift solutions to the previous global p+$^3$He elastic scattering database below 12 MeV. These new measurements, along with measurements of cross-section and beam-analyzing power made over a similar energy range by Fisher \\textit{et al.}, allowed a single, unique solution to be obtained. The new measurements and phase-shifts are compared with theoretical calculations using realistic nucleon-nucleon potential models.

  15. Neutron radiography of a static density gradient of 3He gas at cryogenic temperatures

    Science.gov (United States)

    Wichmann, G.; Antognini, A.; Eggenberger, A.; Kirch, K.; Piegsa, F. M.; Soler, U.; Stahn, J.; Taqqu, D.

    2016-04-01

    We demonstrate a stationary helium gas density gradient which is needed for a proposed novel low-energy μ+ beam line. In a closed system with constant pressure the corresponding density gradient is only a function of the temperature. In a neutron radiography experiment two gas cells with different geometries were filled with 3He gas at constant pressures of about 10 mbar. Temperatures in the range from 6 K to 40 K were applied and density distributions with a maximum to minimum density ratio of larger than 3 were realized. The distribution was investigated employing the strongly neutron absorbing isotope 3He. A simple one-dimensional approach derived from Fourier's law describes the obtained gas density with a deviation < 2 %.

  16. Posture-Dependent Human 3He Lung Imaging in an Open Access MRI System: Initial Results

    CERN Document Server

    Tsai, L L; Li, C -H; Rosen, M S; Patz, S; Walsworth, R L

    2007-01-01

    The human lung and its functions are extremely sensitive to orientation and posture, and debate continues as to the role of gravity and the surrounding anatomy in determining lung function and heterogeneity of perfusion and ventilation. However, study of these effects is difficult. The conventional high-field magnets used for most hyperpolarized 3He MRI of the human lung, and most other common radiological imaging modalities including PET and CT, restrict subjects to lying horizontally, minimizing most gravitational effects. In this paper, we briefly review the motivation for posture-dependent studies of human lung function, and present initial imaging results of human lungs in the supine and vertical body orientations using inhaled hyperpolarized 3He gas and an open-access MRI instrument. The open geometry of this MRI system features a "walk-in" capability that permits subjects to be imaged in vertical and horizontal positions, and potentially allows for complete rotation of the orientation of the imaging su...

  17. Laboratory tests of a modified {sup 3}He detector for use with startup instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Qian, T.; Tonner, P.; Keller, N. [Atomic Eerngy of Canada Limited, Chalk River, ON (Canada)] [and others

    1997-07-01

    Boron trifluoride (BF{sub 3}) detectors are currently used in all CANDU stations as startup instrumentation (SUI) detectors for monitoring neutron flux during extended outages and startups. Experience at some CANDU stations has shown that some models of BF{sub 3} detectors degrade quickly, even in moderate neutron and gamma fields. Degradation and life expectancy tests for five models of BF{sub 3} detectors from different manufacturers were performed at Chalk River Laboratories (CRL) to investigate the problem. The test results reveal that most BF{sub 3} detectors have low neutron and gamma durability, and some exhibit an undesirable time-dependent degradation followed by recovery. As a result of this finding, other detector options including a modified helium ({sup 3}He) detector described herein were investigated. Modified {sup 3}He detectors were procured from an established supplier and were found to perform without degradation in neutron and gamma fields. (author)

  18. A Light-Front Approach to the 3He Spectral Function

    Science.gov (United States)

    Scopetta, Sergio; Del Dotto, Alessio; Kaptari, Leonid; Pace, Emanuele; Rinaldi, Matteo; Salmè, Giovanni

    2015-09-01

    The analysis of semi-inclusive deep inelastic electron scattering off polarized 3He at finite momentum transfers, aimed at the extraction of the quark transverse-momentum distributions in the neutron, requires the use of a distorted spin-dependent spectral function for 3He, which takes care of the final state interaction effects. This quantity is introduced in the non-relativistic case, and its generalization in a Poincaré covariant framework, in plane wave impulse approximation for the moment being, is outlined. Studying the light-front spin-dependent spectral function for a J = 1/2 system, such as the nucleon, it is found that, within the light-front dynamics with a fixed number of constituents and in the valence approximation, only three of the six leading twist T-even transverse-momentum distributions are independent.

  19. A Light-Front approach to the $^3$He spectral function

    CERN Document Server

    Scopetta, Sergio; Kaptari, Leonid; Pace, Emanuele; Rinaldi, Matteo; Salmè, Giovanni

    2014-01-01

    The analysis of semi-inclusive deep inelastic electron scattering off polarized $^3$He at finite momentum transfers, aimed at the extraction of the quark transverse-momentum distributions in the neutron, requires the use of a distorted spin-dependent spectral function for $^3$He, which takes care of the final state interaction effects. This quantity is introduced in the non-relativistic case, and its generalization in a Poincar\\'e covariant framework, in plane wave impulse approximation for the moment being, is outlined. Studying the light-front spin-dependent spectral function for a J=1/2 system, such as the nucleon, it is found that, within the light-front dynamics with a fixed number of constituents and in the valence approximation, only three of the six leading twist T-even transverse-momentum distributions are independent.

  20. Application of δ18O, δD, 3H-3He and CFCs to characterize the nitrate contamination of groundwater in Eumsung, Korea

    Science.gov (United States)

    Ju, Y. J.; Kaown, D.; Hahm, D.; Kim, I.; Lee, S. S.; Koh, E. H.; Kim, M.; Yoon, Y. Y.; Lee, K. K.

    2015-12-01

    We measured the major ions, stable oxygen and hydrogen isotopes, 3H-3He and CFCs concentration in groundwater to identify the characteristics of nitrate contamination and to understand the groundwater recharge patterns. In this study, 17 groundwater samples were collected for 5days (from March 3rd to 7th, 2015) in Eumseong, Korea. In the study area, NO3- concentrations in some groundwater samples (16 of 17) ranged from 5.7 to 103.7 mg/L (avg. 43.3 mg/L), which were substantially higher than the drinking water quality standard (10 mg/L). These excess NO3- inputs in groundwater seem to be originated from the agricultural use of chemical fertilizers because major ions associated with fertilizers were significantly correlated with NO3-. It seems that major groundwater recharge event during monsoon season is highly probable from the analysis of δ18O and δD. The apparent groundwater age using 3H-3He and CFCs varies from 5 to 40 yrs although the study area is small (1 km2). For the samples showed large deficiency of 3He, the sensitivity analysis was performed using NOBLE 90 in an effort to quantify the degassed amount. Since nitrate sources are quite evenly distributed through the field site, groundwater ages from shallow aquifer is inversely correlated with the nitrate concentrations. Our result implies that the 3H-3He ratio can be a useful indicator of tracing the recharge pattern of groundwater but also the nitrate loading characteristic in a small scale agricultural area. Acknowlegments: Financial support was provided by the "R&D Project on Environmental Management of Geologic CO2 Storage" from the KEITI (Project Number: 2014001810003) and the research project of "Advanced Technology for Groundwater Development and Application in Riversides (Geowater+)" in "Water Resources Management Program (code 11 Technology Innovation C05)" of the MOLIT and the KAIA in Korea.

  1. Experiment E89-044 on the Quasielastic 3He(e,e'p) Reaction at Jefferson Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    E. Penel-Nottaris

    2004-07-07

    The Jefferson Lab Hall A E89-044 experiment has measured the 3He(e,e'p) reaction cross-sections. The extraction of the longitudinal and transverse response functions for the two-body break-up 3He(e,e'p)d reaction in parallel kinematics allows the study of the bound proton electromagnetic properties inside the 3He nucleus and the involved nuclear mechanisms beyond plane wave approximations.

  2. Energy dissipation and multifragment decay in the 3He+natAg system

    International Nuclear Information System (INIS)

    Multifragment emission data from the 3He+Ag reaction are examined in the context of an intranuclear cascade code followed by an expanding, emitting source calculation. The role of Δ resonances in the energy dissipation process is stressed. In addition, the importance of employing a distribution of excitation energies in such analyses is pointed out. In order to describe the data within the context of this hybrid model, excitation via Δ resonance formation and expansion of the emitting source are required

  3. Positive parity levels populated in the 17O(3He,p)19F reaction

    International Nuclear Information System (INIS)

    Positive parity levels in 19F populated in the 17O(3He,p) reaction are studied upto Esub(x) approx.=7 MeV. The angular distributions of the levels are studied in terms of the DWBA method of single-step process using two-particle spectroscopic amplitudes derived from (sd) shell model calculations. The difference in shape presented by different levels of the same Jsup(π)-value is well given by the shell model amplitudes. (author)

  4. Orienting effect of vortices on the directrix of rotating 3He--B

    International Nuclear Information System (INIS)

    The combined effect of a magnetic field and superfluid vortex flows on the equilibrium orientation of the directrix of rotating 3He--B is theoretically investigated. It is shown that the presence of vortices is revealed by a shift in the transverse-NMR frequency, the effect being greatest when the external magnetic field is inclined at an angle of theta = π/4 to the axis of rotation

  5. Continuous vortices with broken symmetry in rotating superfluid 3He-A

    International Nuclear Information System (INIS)

    New NMR measurements are reported on continuous 3He-A vortices in tilted magnetic fields. We introduce a symmetry classification of the continuous vortices with broken axial symmetry. It is found that the discrete internal symmetry may in addition be broken in two inequivalent ways, producing two different continuous vortices. Although NMR may not distinguish between these two vortices, the observed vortex satellite peak is well accounted for by spin waves localized in the soft cores of such vortices

  6. A search for disordered (glassy) phase in solid 3He deformed in situ

    OpenAIRE

    Lisunov, A. A.; Maidanov, V. A.; Rubanskiy, V. Yu.; Rubets, S. P.; Rudavskii, E. Ya.; Rybalko, A. S.; Tikhii, V. A.

    2010-01-01

    A disordered (glassy) state has been searched in solid 3He deformed in the course of experiment employing precise measurements of pressure. The analysis of the temperature dependence of the crystal pressure measured at a constant volume shows that the main contribution to the pressure is made by the phonon subsystem, the influence of the disordered phase being very weak. Annealing of the deformed crystal does not affect this state. The results obtained differ greatly from the corresponding da...

  7. Testing on novel neutron detectors as alternative to 3He for security applications

    International Nuclear Information System (INIS)

    Detection of illicit trafficking of nuclear material relies on the detection of the radiation emitted. In the case of plutonium, one of the characteristic signatures derives from neutron emission. For this reason, neutron detectors cover an important role in detection systems. Most current neutron detection systems used for nuclear security are based on the 3He technology. Unfortunately, in the last few years the market of 3He has encountered huge problems in matching the supply and the demand. The need has grown significantly due to the increasing demand of instrumentation for security. This has caused an exponential increase of the price from one side and on the other side a serious strategic problem of resources. In order to guarantee the availability of detection systems for nuclear security, it is necessary to develop alternative detection systems based on technologies different from 3He. Many research projects have been devoted for the development of novel neutron detectors both by research organisations and by industries. Scientists from the PERLA laboratory of the Joint Research Centre (JRC) in Ispra, Italy, and their collaborators have tested several of these novel concepts in the last couple of years. This paper describes the detector systems tested at JRC and preliminary results on detectors that can be considered as promising alternatives to 3He. -- Highlights: ► The paper tackles the problem of lack of He-3 supply. ► This impacts neutron detection for security applications. ► The aim is to test innovative/alternative solutions for neutron detectors. ► Encouraging results obtained with organic and Li-based scintillators.

  8. Diffraction model analysis of polarized triton and 3He elastic scattering

    International Nuclear Information System (INIS)

    The differential cross-section and analyzing power angular distributions are presented for the elastic scattering of polarized 3H from 40Ca and 58Ni at 17MeV and 3He from 26Mg, 27Al and 58Ni at different energies. The data obtained for spin 1/2 strongly absorbed particles elastically scattered by spinless targets are analyzed by the diffraction model. (author)

  9. Isotopic separation of 3He/4He from solar wind gases evolved from the lunar regolith

    International Nuclear Information System (INIS)

    The potential benefits of 3He when utilized in a nuclear fusion reactor to provide clean, safe electricity in the 21st century for the world's inhabitants has been documented. Unfortunately, He is scarce on earth. Large quantities of 3He, perhaps a million tonnes, are embedded in the lunar regolith, presumably implanted by the solar wind together with other elements, notably 4He, H, C and N. Several studies have suggested processing the lunar regolith and recovering these valuable solar wind gases. Once released, these gases can be separated for use. The separation of helium isotopes is described in this paper. 3He constitutes only 400 at·ppm of lunar He, too dilute to separate economically by distillation alone. A ''superfluid'' separator is being considered to preconcentrate the 3He. The superfluid separator consists of a porous filter in a tube maintained at a temperature of 2.17 K or less. Although the 4He, which is superfluid below 2.17 K, flows readily through the filter, the He is blocked by the filter, and becomes enriched at the feed end. He can be enriched to about 10% in such a system. The enriched product from the superfluid separation serves as a feed to a distillation apparatus operating at a pressure of 9 kPa, with a boiler temperature of 2.4 K, and a condenser temperature of 1.6 K. Under constant flow conditions, a 99.9% enriched He product can be produced in this apparatus. The heat rejection load of the refrigeration equipment necessary to cool the separation operations would be conducted during the lunar nights

  10. Final-State Spectrum of $^3$He after $\\beta^-$ Decay of Tritium Anions T$^-$

    OpenAIRE

    Stark, Alexander; Saenz, Alejandro

    2009-01-01

    The final-state spectrum of $\\beta$ decaying tritium anions T$^-$ was calculated. The wavefunctions describing the initial T$^-$ ground state and the final $^3$He states were obtained by the full configuration-interaction method. The transition probability was calculated within the sudden approximation. The transition probability into the electronic continuum is extracted from the complex-scaled resolvent and is shown to converge for very high-energies to an approximate analytical model proba...

  11. Discrete nuclear-elastic-scattering effects in Cat-D and D-3He fusion plasmas

    International Nuclear Information System (INIS)

    The effects of Nuclear Elastic Scattering (NES) of fusion products are investigated for Cat-D and D-3He plasmas. It is found that accounting for the discrete nature of the large energy transfer associated with NES is necessary to accurately calculate the plasma distribution functions, and effects on overall plasma characteristics such as ignition requirements. For cases where cyclotron losses are important, inclusion of NES can reduce the ignition requirements by 50%

  12. A broadband Ytterbium-doped tunable fiber laser for 3He optical pumping at 1083 nm

    OpenAIRE

    Tastevin, Geneviève; Grot, Sébastien; Courtade, Emmanuel; Bordais, Sylvain; Nacher, Pierre-Jean

    2004-01-01

    Submitted: July 2003, Published online: December 2003, Published: Appl. Phys. B 78 (2004) 145-156. Copyright : Springer-Verlag 2003 (http://www.springerlink.com). V3: symbols corrected in Figs 10-11; minor final changes included. Large amounts of hyperpolarized 3He gas with high nuclear polarization rates are required for use in neutron spin filters or nuclear magnetic resonance imaging of human lung. Very high efficiency can be obtained by metastability exchange optical pumping using mult...

  13. Saddle point condition for D minus sup 3 He tokamak fusion reactor

    Energy Technology Data Exchange (ETDEWEB)

    Mitarai, O. (Kumamoto Inst. of Technology, Dept. of Electrical Engineering, Ikeda 4-22-1, Kumamoto 860 (JP)); Hirose, A.; Skarsgard, H.M. (Univ. of Saskatchewan, Dept. of Physics Sasakatoon, Saskatchewan, S7N 0W0 (CA))

    1991-03-01

    In this paper the concept of a generalized ignition contour map, showing {bar P}{sub ht}T{sup 2}{sub E}, NT{sub E}, and T, is used to study the ignition criterion for a D{minus}{sup 3}He fusion reactor with plasma temperature and density profiles. Direct heating scenarios to the D {minus} {sup 3}He ignition regime without the help of deuterium-tritium burning are considered. The machine size and enhancement factor for the confinement time required to reach D {minus} {sup 3}He ignition can be simple determined by comparing the height of the operation path with Goldston L-mode scaling and the height of the generalized saddle point. A confinement enhancement factor of 2 to 3 is required in the case of a large plasma current (30 to 80 MA) in a small-aspect-ratio tokamak. On the other hand, for a small plasma current ({approx lt} 10 MA), large-aspect-ratio tokamak, an enhancement factor of 5 to 6 is necessary to reach ignition. Fuel dilution effects by fusion products and impurities, the confinement degradation effect due to 14-MeV protons, and the operation paths are also considered. To lower the height of the saddle point, and hence the auxiliary heating power, we optimize the fuel composition and examine operation in the hot ion mode.

  14. A microscopic cluster model study of $^3$He+$p$ scatterings

    CERN Document Server

    Arai, K; Suzuki, Y

    2008-01-01

    We calculate $^3$He+$p$ scattering phase shifts in two different microscopic cluster models, Model T and Model C, in order to show the effects of tensor force as well as $D$-wave components in the cluster wave function. Model T employs a realistic nucleon-nucleon potential and includes the $D$-wave, whereas Model C employs an effective potential in which the tensor-force effect is considered to be renormalized into the central force and includes only the $S$-wave for the cluster intrinsic motion. The $S$- and $P$-wave elastic scattering phase shifts are obtained in the \\{$^3$He+$p$\\}+\\{$d$ + 2$p$\\} coupled-channels calculation. In Model T, the $d$ + 2$p$ channel plays a significant role in producing the $P$-wave resonant phase shifts but hardly affects the $S$-wave non-resonant phase shifts. In Model C, however, the effect of the $d$ + 2$p$ channel is suppressed in both of the $S$- and $P$-wave phase shifts, suggesting that it is renormalized mostly as the $^3$He(1/2$^+$)+$p$ channel in the resonance region.

  15. First measurement of unpolarized SIDIS cross section and cross section ratios from a $^3$He target

    CERN Document Server

    Yan, X; Aniol, K; Annand, J R M; Averett, T; Benmokhtar, F; Bertozzi, W; Bradshaw, P C; Bosted, P; Camsonne, A; Canan, M; Cates, G D; Chen, C; Chen, J -P; Chen, W; Chirapatpimol, K; Chudakov, E; Cisbani, E; Cornejo, J C; Cusanno, F; Dalton, M M; Deconinck, W; de Jager, C W; De Leo, R; Deng, X; Deur, A; Ding, H; Dolph, P A M; Dutta, C; Dutta, D; Fassi, L El; Frullani, S; Gao, H; Garibaldi, F; Gaskell, D; Gilad, S; Gilman, R; Glamazdin, O; Golge, S; Guo, L; Hamilton, D; Hansen, O; Higinbotham, D W; Holmstrom, T; Huang, J; Huang, M; Ibrahim, H F; Iodice, M; Jiang, X; Jin, G; Jones, M K; Katich, J; Kelleher, A; Kim, W; Kolarkar, A; Korsch, W; LeRose, J J; Li, X; Li, Y; Lindgren, R; Liu, T; Liyanage, N; Long, E; Lu, H -J; Margaziotis, D J; Markowitz, P; Marrone, S; McNulty, D; Meziani, Z -E; Michaels, R; Moffit, B; Camacho, C Munoz; Nanda, S; Narayan, A; Nelyubin, V; Norum, B; Oh, Y; Osipenko, M; Parno, D; Peng, J -C; Phillips, S K; Posik, M; Puckett, A J R; Qian, X; Qiang, Y; Rakhman, A; Ransome, R; Riordan, S; Saha, A; Sawatzky, B; Schulte, E; Shahinyan, A; Shabestari, M H; Sirca, S; Stepanyan, S; Subedi, R; Sulkosky, V; Tang, L -G; Tobias, W A; Urciuoli, G M; Vilardi, I; Wang, K; Wojtsekhowski, B; Wang, Y; Yan, X; Yao, H; Ye, Y; Ye, Z; Yuan, L; Zhan, X; Zhang, Y; Zhang, Y -W; Zhao, B; Zhao, Y X; Zheng, X; Zhu, L; Zhu, X; Zong, X

    2016-01-01

    The unpolarized semi-inclusive deep-inelastic scattering (SIDIS) differential cross sections in $^3$He($e,e^{\\prime}\\pi^{\\pm}$)$X$ have been measured for the first time in Jefferson Lab experiment E06-010 performed with a $5.9\\,$GeV $e^-$ beam on a $^3$He target. The experiment focuses on the valence quark region, covering a kinematic range $0.12 < x_{bj} < 0.45$, $1 < Q^2 < 4 \\, \\textrm{(GeV/c)}^2$, $0.45 < z_{h} < 0.65$, and $0.05 < P_t < 0.55 \\, \\textrm{GeV/c}$. The extracted SIDIS differential cross sections of $\\pi^{\\pm}$ production are compared with existing phenomenological models while the $^3$He nucleus approximated as two protons and one neutron in a plane wave picture, in multi-dimensional bins. Within the experimental uncertainties, the azimuthal modulations of the cross sections are found to be consistent with zero.

  16. A New 3He-Target Design for Compton Scattering Experiment

    Science.gov (United States)

    Mahalchick, S.; Gao, H.; Laskaris, G.; Weir, W.; Ye, Q.; Ye, Q. J.

    2011-10-01

    The neutron spin polarizabilities describe the stiffness of the neutron spin to external electric and magnetic fields. A double-polarized elastic Compton Scattering experiment will try to determine the neutron spin polarizabilities using a new polarized 3He target and the circularly polarized γ-beam of HI γS facility at the Duke Free Electron Laser Laboratory (DFELL). To polarize the 3He target, a newly constructed solenoid is being used which can provide a very uniform magnetic field around the target area and allows to place High Intensity Gamma Source NaI Detector Arrays (HINDA) closer to the target. The ideal target polarization is 40-60% and will be measured using the nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) techniques. A prototype of the polarized 3He target is being constructed in the Medium Energy Physics Group laboratories at Duke and is currently being tested. The experiment is expected to take place in 2013 after the DFELL upgrade. I will be presenting details of the construction process, including design specifications and data from the magnetic field mapping, as well as preliminary target polarization results. This work is supported by the US Department of Energy, under contract number DE-FG02-03ER41231, and by the National Science Foundation, grant number NSF-PHY-08-51813.

  17. Spin correlation parameter Cyy of p+3He elastic backward scattering

    International Nuclear Information System (INIS)

    We measured the differential cross section and the spin correlation parameter Cyy of the p-vector+3He-vector elastic backward scattering at 200, 300, and 400 MeV at θ=180 deg. in the center-of-mass frame to study the mechanism of the reaction and to examine the validity of the 3He wave functions based on two different realistic two-body forces. This is the first measurement of the spin correlation parameter Cyy of the p-vector+3He-vector EBS at intermediate energies. The experimental results were compared with few-body calculations, including three reaction mechanisms: two-nucleon-pair exchange, pion exchange, and direct pp scattering. It was found that few-body calculations describe the differential cross-section data reasonably well. The spin correlation parameter Cyy shows clear evidence for the two-nucleon-pair exchange processes in the reaction, demonstrating that the spin observables are helpful for deeper understanding of the reaction mechanism

  18. A 3 He-129 Xe co-magnetometer with 87 Rb magnetometry

    Science.gov (United States)

    Limes, Mark; Sheng, Dong; Romalis, Mike

    2016-05-01

    We report progress on a 3 He-129 Xe co-magnetometer detected with a 87 Rb magnetometer. The noble-gas co-magnetometer is insensitive to any long-term bias field drifts, but the presence of hot Rb can cause instability in the ratio of 3 He-129 Xe precession frequencies. We use a sequence of Rb π pulses to suppress the instability due to Rb-noble gas interactions by a factor of 104 along all three spatial axes. For detection, our 87 Rb magnetometer operates using single-axis 87 Rb π pulses with σ+ /σ- pumping-this technique decouples the 87 Rb magnetometer from bias fields, and allows for SERF operation. We are presently investigating systematic effects due to combinations of several imperfections, such as longitudinal noble gas polarization, imperfect 87 Rb π pulses, and 87 Rb pump light shifts. Thus far, our 87 Rb magnetometer has a sensitivity of 40 fT/√{Hz}, and our 3 He-129 Xe co-magnetometer has achieved a single-shot precession frequency ratio error of 20 nHz and a long-term bias drift of 8 nHz at 7 h. We are developing the co-magnetometer for use as an NMR gyro, and to search for possible spin-gravity interactions. Supported by DARPA and NSF.

  19. Hyperpolarized 3He Functional Magnetic Resonance Imaging of Bronchoscopic Airway Bypass in Chronic Obstructive Pulmonary Disease

    Directory of Open Access Journals (Sweden)

    Lindsay Mathew

    2012-01-01

    Full Text Available A 73-year-old exsmoker with Global initiative for chronic Obstructive Lung Disease stage III chronic obstructive pulmonary disease underwent airway bypass (AB as part of the Exhale Airway Stents for Emphysema (EASE trial, and was the only EASE subject to undergo hyperpolarized 3He magnetic resonance imaging for evaluation of lung function pre- and post-AB. 3He magnetic resonance imaging was acquired twice previously (32 and eight months pre-AB and twice post-AB (six and 12 months post-AB. Six months post-AB, his increase in forced vital capacity was <12% predicted, and he was classified as an AB nonresponder. However, post-AB, he also demonstrated improvements in quality of life scores, 6 min walk distance and improvements in 3He gas distribution in the regions of stent placement. Given the complex relationship between well-established pulmonary function and quality of life measurements, the present case provides evidence of the value-added information functional imaging may provide in chronic obstructive pulmonary disease interventional studies.

  20. Chiral effective field theory predictions for muon capture on deuteron and {3}He.

    Science.gov (United States)

    Marcucci, L E; Kievsky, A; Rosati, S; Schiavilla, R; Viviani, M

    2012-02-01

    The muon-capture reactions {2}H(μ{-},ν{μ})nn and {3}He(μ{-},ν{μ}){3}H are studied with nuclear potentials and charge-changing weak currents, derived in chiral effective field theory. The low-energy constants (LECs) c{D} and c{E}, present in the three-nucleon potential and (c{D}) axial-vector current, are constrained to reproduce the A=3 binding energies and the triton Gamow-Teller matrix element. The muon-capture rates on deuteron and {3}He are predicted to be 399±3  sec{-1} and 1494±21  sec{-1}, respectively. The spread accounts for the cutoff sensitivity, as well as uncertainties in the LECs and electroweak radiative corrections. By comparing the calculated and precisely measured rates on {3}He, a value for the induced pseudoscalar form factor is obtained in good agreement with the chiral perturbation theory prediction. PMID:22400928

  1. Chiral effective field theory predictions for muon capture on deuteron and $^3$He

    Energy Technology Data Exchange (ETDEWEB)

    Laura E. Marcucci, A. Kievsky, S. Rosati, R. Schiavilla, M. Viviani

    2012-01-01

    The muon-capture reactions {sup 2}H({mu}{sup -}, {nu}{sub {mu}})nn and {sup 3}He({mu}{sup -},{nu}{sub {mu}}){sup 3}H are studied with nuclear strong-interaction potentials and charge-changing weak currents, derived in chiral effective field theory. The low-energy constants (LEC's) c{sub D} and c{sub E}, present in the three-nucleon potential and (c{sub D}) axial-vector current, are constrained to reproduce the A=3 binding energies and the triton Gamow-Teller matrix element. The vector weak current is related to the isovector component of the electromagnetic current via the conserved-vector-current constraint, and the two LEC's entering the contact terms in the latter are constrained to reproduce the A=3 magnetic moments. The muon capture rates on deuteron and {sup 3}He are predicted to be 399 {+-} 3 sec{sup -1} and 1494 {+-} 21 sec{sup -1}, respectively, where the spread accounts for the cutoff sensitivity as well as uncertainties in the LEC's and electroweak radiative corrections. By comparing the calculated and precisely measured rates on {sup 3}He, a value for the induced pseudoscalar form factor is obtained in good agreement with the chiral perturbation theory prediction.

  2. Comparison of various stopping gases for {sup 3}He-based position sensitive neutron detectors

    Energy Technology Data Exchange (ETDEWEB)

    Doumas, A. [United States Merchant Marine Academy, Steamboat Road, Kings Point, NY 11024 (United States); Smith, G.C., E-mail: gsmith@bnl.gov [Instrumentation Division, Brookhaven National Laboratory, Upton, NY 11973 (United States)

    2012-05-21

    A range of solid state, scintillator and gas based detectors are being developed for use at the next generation of high flux neutron facilities. Since gas detectors are expected to continue to play a key role in future specific thermal neutron experiments, a comparison of the performance characteristics of prospective stopping gases is beneficial. Gas detectors typically utilize the reaction {sup 3}He(n,p)t to detect thermal neutrons; the {sup 3}He gas is used in a mixture containing a particular stopping gas in order to maintain relatively short ranges for the proton and triton pair emitted from the n-{sup 3}He reaction. Common stopping gases include hydrocarbons (e.g. propane), carbon tetrafluoride, and noble gases such as argon and xenon. For this study, we utilized the Monte Carlo simulation code 'Stopping and Range of Ions in Matter' to analyze the expected behavior of argon, xenon, carbon dioxide, difluoroethane and octafluoropropane as stopping gases for thermal neutron detectors. We also compare these findings to our previously analyzed performance of propane, butane and carbon tetrafluoride. A discussion of these gases includes their behavior in terms of proton and triton range, ionization distribution and straggle.

  3. Long-range states in excited ultracold 3He*-4He* dimers

    CERN Document Server

    Cocks, Daniel G; Whittingham, Ian B

    2014-01-01

    Long-range bound states of the excited heteronuclear 3He*--4He* system that dissociate to either 3He(1s2s 3S_1) + 4He(1s2p 3P_j) or 3He(1s2p 3P_j) + 4He(1s2s 3S_1), where j=0, 1, 2, are investigated using both single-channel and multichannel calculations in order to analyse the effects of Coriolis and non-adiabatic couplings. The multichannel calculations predict two groups of resonances above the lowest asymptotic energy. One of these groups dissociates to an atomic pair with the 2p excitation on the fermionic atom and the other dissociates to two asymptotes which correspond to the 2p excitation on either atom. Many of these resonances could be identified with levels in the single-channel calculation although the differences in energies were large. The total parity was found to have a significant influence on the ability to make these identifications. No purely bound states were found, although several resonances with line widths smaller than 1 MHz were obtained.

  4. Hyperpolarised sup 3 He gas production for magnetic resonance imaging of the human air ways

    CERN Document Server

    Fichele, S

    2002-01-01

    This thesis describes the experimental techniques, and methods employed in hyperpolarised sup 3 He gas production and magnetic resonance imaging of the human air-ways, using spin-echo sequences and MR tagging techniques. An in-house polariser utilising the metastability optical pumping technique was constructed. The main results of this work are concerned with engineering difficulties involved in compressing HP sup 3 He and a large proportion of this PhD thesis details the design, construction, and performance of an in-house built peristaltic compressor. In preliminary imaging experiments using RARE, high signal to noise projection images of the lungs were acquired using less than 0.5 cm sup 3 (STP) of purely polarised HP gas. Later, increased HP gas quantities (typically 10 cm sup 3) were obtained by employing the peristaltic compressor. Consequently we could acquire 10 mm thick slices spanning the entire lung following a single sup 3 He gas bolus administration. Finally, the first results using MR tagging t...

  5. Significance of apparent diffusion coefficient measurement for the differential diagnosis of multiple system atrophy, progressive supranuclear palsy, and Parkinson's disease: evaluation by 3.0-T MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Tsukamoto, Kazumichi; Kanasaki, Yoshiko; Kakite, Suguru; Fujii, Shinya; Kaminou, Toshio; Ogawa, Toshihide [Tottori University, Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Yonago, Tottori (Japan); Matsusue, Eiji [Tottori Prefectural Central Hospital, Department of Radiology, Tottori (Japan)

    2012-09-15

    The clinical differentiation of Parkinson's disease (PD) from multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) may be challenging, especially in their early stages. The aim of this study was to evaluate the utility of apparent diffusion coefficient (ADC) measurement to distinguish among these degenerative disorders. Twenty-five MSA, 20 PSP, and 17 PD patients and 18 healthy controls were retrospectively studied. Axial diffusion-weighted and T2-weighted images were obtained using a 3-T MR system. Regions of interest (ROIs) were precisely placed in the midbrain, pons, putamen, globus pallidus, caudate nucleus, thalamus, superior cerebellar peduncle, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus, and the regional ADC (rADC) value was calculated in each ROI. In MSA, rADC values in the pons, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus were significantly higher than in PSP, PD, and controls. Furthermore, rADC values in the posterior putamen were significantly higher in MSA than in PSP and controls. In PSP, rADC values were significantly higher in the globus pallidus and midbrain than in MSA, PD, and controls. Furthermore, rADC values in the caudate nucleus and superior cerebellar peduncle were significantly higher in PSP than in MSA and controls. In PD, there were no significant differences in the rADC values compared to in MSA, PSP, and controls in all regions. Evaluation of rADC values in characteristic lesions in MSA, PSP, and PD by placing ROIs using 3-T systems can provide useful additional information for differentiating these disorders. (orig.)

  6. Precision Measurement of the Spin-dependent Asymmetry in the Threshold Region of Quasielastic 3He

    Energy Technology Data Exchange (ETDEWEB)

    Feng Xiong

    2002-09-01

    The first precision measurement of the spin-dependent asymmetry in the threshold region of polarized {sup 3}He(polarized e, e') was carried out in Hall A at the Jefferson Laboratory, using a longitudinally polarized continuous electron beam incident on a high-pressure polarized {sup 3}He gas target. The polarized electron beam was generated by illuminating a strained GaAs cathode with high intensity circularly polarized laser light, and an average beam polarization of about 70% was achieved. The {sup 3}He target was polarized based on the principle of spin-exchange optical pumpint and the average target polarization was about 30%. The scattered electrons were detected in the two Hall A high resolution spectrometers, HRSe and HRSh. The data from HRSh were used for this analysis and covered both the elastic peak and the threshold region. Two kinematic points were measured in the threshold region, one with a central Q{sup 2}-value of 0.1 (GeV/c){sup 2} at an incident beam energy E{sub 0} = 0.778 GeV and the other with a central Q{sup 2}-value of 0.2 (GeV/c){sup 2} at E-0 = 1.727 GeV. The average beam current was 10 mu-A, which was mainly due to the limitation of the polarized {sup 3}He target. The measured asymmetry was compared with both plane wave impulse approximation (PWIA) calculations and non-relativistic full Faddeev calculations which include both final-state interactions (FSIs) and meson-exchange currents (MECs) effects. The poor description of the data by PWIA calculations at both Q{sup 2}-values suggests the existence of strong FSI and MEC effects in the threshold region of polarized {sup 3}He (polarized e, e'). Indeed, the agreement between the data and full calculations is very good at Q{sup 2} = 0.1 (GeV/c){sup 2}. On the other hand, a small discrepancy at Q{sup 2} = 0.2 (GeV/c){sup 2} is observed, which might be due to some Q{sup 2} -dependent effects such as relativity and three-nucleon forces (3NFs), which are not included in the framework

  7. Safety analysis of high pressure 3He-filled micro-channels for thermal neutron detection.

    Energy Technology Data Exchange (ETDEWEB)

    Ferko, Scott M.; Galambos, Paul C.; Derzon, Mark Steven; Renzi, Ronald F.

    2008-11-01

    This document is a safety analysis of a novel neutron detection technology developed by Sandia National Laboratories. This technology is comprised of devices with tiny channels containing high pressure {sup 3}He. These devices are further integrated into large scale neutron sensors. Modeling and preliminary device testing indicates that the time required to detect the presence of special nuclear materials may be reduced under optimal conditions by several orders of magnitude using this approach. Also, these devices make efficient use of our {sup 3}He supply by making individual devices more efficient and/or extending the our limited {sup 3}He supply. The safety of these high pressure devices has been a primary concern. We address these safety concerns for a flat panel configuration intended for thermal neutron detection. Ballistic impact tests using 3 g projectiles were performed on devices made from FR4, Silicon, and Parmax materials. In addition to impact testing, operational limits were determined by pressurizing the devices either to failure or until they unacceptably leaked. We found that (1) sympathetic or parasitic failure does not occur in pressurized FR4 devices (2) the Si devices exhibited benign brittle failure (sympathetic failure under pressure was not tested) and (3) the Parmax devices failed unacceptably. FR4 devices were filled to pressures up to 4000 + 100 psig, and the impacts were captured using a high speed camera. The brittle Si devices shattered, but were completely contained when wrapped in thin tape, while the ductile FR4 devices deformed only. Even at 4000 psi the energy density of the compressed gas appears to be insignificant compared to the impact caused by the incoming projectile. In conclusion, the current FR4 device design pressurized up to 4000 psi does not show evidence of sympathetic failure, and these devices are intrinsically safe.

  8. Neutron production rates during four transitions from DT to D3He ignited plasmas in a compact tokamak

    International Nuclear Information System (INIS)

    Neutron production rates (due to DT, DD, TT and T3He reactions) and D3He reaction rate during four transitions from DT to D3He ignited plasmas (characterized by different evolutions of ion densities and temperature) in a compact tokamak have been calculated. In this paper, for each transition, the results are reported in graphical form (one curve for each reaction) and shortly discussed. The main feature is the predominance of 14 MeV DT-neutrons, whose production rate does not appear to be negligible. It is therefore concluded that while acceptable in experiments of D3He ignition, tritium-assistance may not be suitable for routine startup of D3He fusion power plants, in which plasma temperature will hae to be raised to ignition level probably by other means. Mention to a program aimed at measuring cross sections of some neutron-lean fusion reactions is also made

  9. Barshay-Temmer test for the 4He( overlined, 3He) 3H reaction

    Science.gov (United States)

    Bruno, M.; Cannata, F.; D'agostino, M.; Fiandri, M. L.; Herman, M.; Hofmann, H. M.; Vuaridel, B.; Grüebler, W.; König, V.; Schmelzbach, P. A.; Elsener, K.

    1989-09-01

    The mechanisms of isospin violation in the reaction 4He( overlined, 3He) 3H is studied, in the framework of a microscopic model. To describe realistically the intermediate 6Li nucleus and the fragment states we use the refined resonating group model (RRGM). A detailed analysis of the matrix elements responsible for the asymmetry of cross sections and vector analyzing powers is presented. The isospin violation is found typically of the order of 5-10% and arises mainly from coupling to intermediate "5 + 1" structures in a two-step mechanism. The agreement with the experimental data is fair.

  10. Additional Beta due to Fast Fusion Products in D-3He Fusion Plasma

    Institute of Scientific and Technical Information of China (English)

    DENG Bai-Quan(邓柏权); G.A.Emmert; PENG Li-Lin(彭利林)

    2003-01-01

    An analytical formula for the additional beta due to fast fusion-born ions is derived by using the slowing-down approximation from the Fokker-Planck equation under the assumption of negligible loss term. It is found that the fast ion beta in a D-3 He fusion plasma at a typical temperature of 55 ke V is about 20% of the thermal beta,which is the same ratio as that obtained in a D-T plasma at 20keV.

  11. A self-contained 3He refrigerator suitable for long duration balloon experiments

    Science.gov (United States)

    Masi, S.; Aquilini, E.; Cardoni, P.; de Bernardis, P.; Martinis, L.; Scaramuzzi, F.; Sforna, D.

    We describe the design, development and test of a self-contained 3He fridge, aimed to cool at ≲0.3 K a bolometric detection system with a hold time of two weeks. The system is robust and suitable for operation on a long-duration stratospheric balloon payload. A physical model of the fridge has been developed, which describes the measured hold time, limiting temperature and load curve of the fridge. The system has been flight tested successfully during two balloon flights of the BOOMERanG payload in summer 1997.

  12. Observations of homogeneous phase separation in liquid He3-He4 mixtures

    Science.gov (United States)

    Hoffer, J. K.; Campbell, L. J.; Bartlett, R. J.

    1980-01-01

    The so-called miscibility gap that exists below the critical point in liquid He-3 - H-4 mixtures makes it possible to study binary phase composition, and the ensuing dispersions, in a system possessing an additional order parameter in one of the components. The physical behavior of a superfluid dispersion produced by pressure quenching an He-3 - He-4 mixture into the miscibility gap is described. The description applies both to quenches of homogeneous and phase-separated initial states in various regions of the miscibility gap.

  13. Single Particle and Fermi Liquid Properties of He-3/--He-4 Mixtures: A Microscopic Analysis

    OpenAIRE

    Krotscheck, E.; Paaso, J.; Saarela, M.; Schoerkhuber, K.; Zillich, R.

    1998-01-01

    We calculate microscopically the properties of the dilute He-3 component in a He-3/--He-4 mixture. These depend on both, the dominant interaction between the impurity atom and the background, and the Fermi liquid contribution due to the interaction between the constituents of the He-3 component. We first calculate the dynamic structure function of a He-3 impurity atom moving in He-3. From that we obtain the excitation spectrum and the momentum dependent effective mass. The pole strength of th...

  14. NMR Response of a Vortex Tangle in Rotating 3He-B

    International Nuclear Information System (INIS)

    Following the injection of vortex loops into an originally vortex-free sample of superfluid 3He-B at T < 0.6Tc, transient states appear which exhibit a modified response in transverse NMR experiments when compared with the response from the final equilibrium state of rectilinear vortices. Here we investigate the NMR response of a model state where a random vortex tangle is assumed to be superimposed on the equilibrium vortex state. We show that this model can qualitatively account for the experimental findings, provided that the tangle is anisotropic

  15. Orientational effect of uniaxially deformed aerogel on the order parameter of superfluid $^3He$

    OpenAIRE

    Surovtsev, E. V.

    2008-01-01

    Effect of uniaxially-deformed aerogel on orientation of the order parameter of superfluid $^3He$ is considered. Approach used takes into account correlations in positions of particles forming aerogel. Calculations show that for the case of the B-like phase in the uniaxially-stretched aerogel deformation on the order of $10^{-2}\\div10^{-4}$ is already strong enough to achieve orientation of the order parameter which is different from that required by magnetic field in bulk liquid. For the A-li...

  16. Manipulating textures of rotating superfluid 3 He- A phase in a single narrow cylinder

    OpenAIRE

    Kunimatsu, T.; Nema, H.; Ishiguro, R; Kubota, M.; Takagi, T; Sasaki, Y.; Ishikawa, O

    2014-01-01

    We investigated order parameter textures of the rotating superfluid 3 He-A phase in a single narrow cylinder witha diameter of about 10 times the dipole coherence length by the cw-NMR method. It is theoretically proposedthat in such a narrow cylinder, a few special textures will appear due to the confinement in a cylindrical geometry.We observed three types of NMR spectra in the A phase. The NMR spectra of the textures were identified bya comparison with the spin waves excited in the NMR pote...

  17. Two-Nucleon Momentum Distributions Measured in 3He(e,e'pp)n

    CERN Document Server

    Niyazov, R A; Weinstein, L B; Adams, G; Ambrozewicz, P; Anciant, E; Anghinolfi, M; Asavapibhop, B; Audit, G; Auger, T; Avakian, H; Bagdasaryan, H; Ball, J P; Barrow, S; Battaglieri, M; Beard, K; Bektasoglu, M; Bellis, M; Benmouna, N; Berman, Barry L; Bianchi, N; Biselli, A S; Boiarinov, S; Bonner, B E; Bouchigny, S; Bradford, R; Branford, D; Brooks, W K; Burkert, V D; Butuceanu, C; Calarco, J R; Carman, D S; Carnahan, B; Cetina, C; Chen, S; Ciciani, L; Cole, P L; Coleman, A; Cords, D; Corvisiero, P; Crabb, D; Crannell, H; Cummings, J P; De Sanctis, E; De Vita, R; Degtyarenko, P V; Denizli, H; Dennis, L; Dharmawardane, K V; Dhuga, K S; Djalali, C; Dodge, G E; Doughty, D C; Dragovitsch, P; Dugger, M; Dytman, S; Dzyubak, O P; Eckhause, M; Egiyan, H; Egiyan, K S; Elouadrhiri, L; Empl, A; Eugenio, P; Fatemi, R; Feuerbach, R J; Ficenec, J; Forest, T A; Funsten, H; Gavalian, G; Gilfoyle, G P; Giovanetti, K L; Girard, P; Gordon, C I O; Griffioen, K; Guidal, M; Guillo, M R; Guo, L; Gyurjyan, V; Hadjidakis, C; Hakobyan, R S; Hardie, J; Heddle, D; Hersman, F W; Hicks, K; Holtrop, M; Hu, J; Hyde-Wright, C E; Ilieva, Y; Ito, M M; Jenkins, D; Joo, K; Jüngst, H G; Kelley, J H; Khandaker, M; Kim, D H; Kim, K Y; Kim, K; Kim, M S; Kim, W; Klein, A; Klein, F J; Klimenko, A V; Klusman, M; Kossov, M; Kramer, L H; Kuang, Y; Kuhn, S E; Kühn, J; Lachniet, J; Laget, J M; Langheinrich, J; Lawrence, D; Ji Li; Lukashin, K; Manak, J J; Marchand, C; McAleer, S; McNabb, J W C; Mecking, B A; Mehrabyan, S S; Melone, J J; Mestayer, M D; Meyer, C A; Mikhailov, K; Mirazita, M; Miskimen, R; Morand, L; Morrow, S A; Muccifora, V; Müller, J; Mutchler, G S; Napolitano, J; Nasseripour, R; Nelson, S O; Niccolai, S; Niculescu, G; Niculescu, I; Niczyporuk, B B; Nozar, M; O'Rielly, G V; Osipenko, M; Park, K; Pasyuk, E A; Peterson, G; Philips, S A; Pivnyuk, N; Pocanic, D; Pogorelko, O I; Polli, E; Pozdniakov, S; Preedom, B M; Price, J W; Prok, Y; Protopopescu, D; Qin, L M; Raue, B A; Riccardi, G; Ricco, G; Ripani, M; Ritchie, B G; Ronchetti, F; Rossi, P; Rowntree, D; Rubin, P D; Sabatie, F; Sabourov, K; Salgado, C; Santoro, J P; Sapunenko, V; Sargsyan, M; Schumacher, R A; Serov, V S; Shafi, A; Sharabyan, Yu G; Shaw, J; Simionatto, S; Skabelin, A V; Smith, E S; Smith, L C; Sober, D I; Spraker, M; Stavinsky, A V; Stepanyan, S; Stoler, P; Strakovsky, I I; Strauch, S; Taiuti, M; Taylor, S; Tedeschi, D J; Thoma, U; Thompson, R; Todor, L; Tur, C; Ungaro, M; Vineyard, M F; Vlassov, A V; Wang, K; Weller, H; Weygand, D P; Whisnant, C S; Wolin, E; Wood, M H; Yegneswaran, A; Yun, J; Zhang, B

    2004-01-01

    We have measured the 3He(e,e'pp)n reaction at 2.2 GeV over a wide kinematic range. The kinetic energy distribution for `fast' nucleons (p > 250 MeV/c) peaks where two nucleons each have 20% or less, and the third nucleon has most of the transferred energy. These fast pp and pn pairs are back-to-back with little momentum along the three-momentum transfer, indicating that they are spectators. Experimental and theoretical evidence indicates that we have measured distorted two-nucleon momentum distributions by striking the third nucleon and detecting the spectator correlated pair.

  18. Second-order perturbation theory for 3He and pd scattering in pionless EFT

    CERN Document Server

    König, Sebastian

    2016-01-01

    This work implements pionless effective field theory with the two-nucleon system expanded around the unitarity limit at second order perturbation theory. The expansion is found to converge well. All Coulomb effects are treated in perturbation theory, including two-photon contributions at next-to-next-to-leading order. After fixing a three-nucleon force to the 3He binding energy at this order, proton-deuteron scattering in the doublet S-wave channel is calculated for moderate center-of-mass momenta.

  19. Two-nucleon momentum distributions measured in 3He(e,e'pp)n.

    Science.gov (United States)

    Niyazov, R A; Weinstein, L B; Adams, G; Ambrozewicz, P; Anciant, E; Anghinolfi, M; Asavapibhop, B; Asryan, G; Audit, G; Auger, T; Avakian, H; Bagdasaryan, H; Ball, J P; Barrow, S; Battaglieri, M; Beard, K; Bektasoglu, M; Bellis, M; Benmouna, N; Berman, B L; Bertozzi, W; Bianchi, N; Biselli, A S; Boiarinov, S; Bonner, B E; Bouchigny, S; Bradford, R; Branford, D; Brooks, W K; Burkert, V D; Butuceanu, C; Calarco, J R; Carman, D S; Carnahan, B; Cetina, C; Chen, S; Ciciani, L; Cole, P L; Coleman, A; Cords, D; Corvisiero, P; Crabb, D; Crannell, H; Cummings, J P; De Sanctis, E; Dashyan, N; DeVita, R; Degtyarenko, P V; Denizli, H; Dennis, L; Dharmawardane, K V; Dhuga, K S; Djalali, C; Dodge, G E; Doughty, D; Dragovitsch, P; Dugger, M; Dytman, S; Dzyubak, O P; Eckhause, M; Egiyan, H; Egiyan, K S; Elouadrhiri, L; Empl, A; Eugenio, P; Fatemi, R; Feuerbach, R J; Ficenec, J; Forest, T A; Funsten, H; Gavalian, G; Gilad, S; Gilfoyle, G P; Giovanetti, K L; Girard, P; Gordon, C I O; Gothe, R W; Griffioen, K; Guidal, M; Guillo, M; Guo, L; Gyurjyan, V; Hadjidakis, C; Hakobyan, R S; Hardie, J; Heddle, D; Hersman, F W; Hicks, K; Holtrop, M; Hu, J; Hyde-Wright, C E; Ilieva, Y; Ingram, W; Ito, M M; Jenkins, D; Joo, K; Juengst, H G; Kelley, J H; Kellie, J; Khandaker, M; Kim, D H; Kim, K Y; Kim, K; Kim, M S; Kim, W; Klein, A; Klein, F J; Klimenko, A V; Klusman, M; Kossov, M; Kramer, L H; Kuang, Y; Kuhn, S E; Kuhn, J; Lachniet, J; Laget, J M; Langheinrich, J; Lawrence, D; Li, Ji; Livingston, K; Lukashin, K; Manak, J J; Marchand, C; McAleer, S; McLauchlan, S; McNabb, J W C; Mecking, B A; Mehrabyan, S; Melone, J J; Mestayer, M D; Meyer, C A; Mikhailov, K; Mirazita, M; Miskimen, R; Morand, L; Morrow, S A; Muccifora, V; Mueller, J; Mutchler, G S; Napolitano, J; Nasseripour, R; Nelson, S O; Niccolai, S; Niculescu, G; Niculescu, I; Niczyporuk, B B; Nozar, M; O'Rielly, G V; Osipenko, M; Park, K; Pasyuk, E; Peterson, G; Philips, S A; Pivnyuk, N; Pocanic, D; Pogorelko, O; Polli, E; Pozdniakov, S; Preedom, B M; Price, J W; Prok, Y; Protopopescu, D; Qin, L M; Raue, B A; Riccardi, G; Ricco, G; Ripani, M; Ritchie, B G; Ronchetti, F; Rossi, P; Rowntree, D; Rubin, P D; Sabatié, F; Sabourov, K; Salgado, C; Santoro, J P; Sapunenko, V; Schumacher, R A; Serov, V S; Shafi, A; Sharabian, Y G; Shaw, J; Simionatto, S; Skabelin, A V; Smith, E S; Smith, L C; Sober, D I; Spraker, M; Stavinsky, A; Stepanyan, S; Stoler, P; Strakovsky, I I; Strauch, S; Taiuti, M; Taylor, S; Tedeschi, D J; Thoma, U; Thompson, R; Todor, L; Tur, C; Ungaro, M; Vineyard, M F; Vlassov, A V; Wang, K; Weller, H; Weygand, D P; Whisnant, C S; Wolin, E; Wood, M H; Yegneswaran, A; Yun, J; Zhang, B

    2004-02-01

    We have measured the 3He(e,e'pp)n reaction at 2.2 GeV over a wide kinematic range. The kinetic energy distribution for "fast" nucleons (p>250 MeV/c) peaks where two nucleons each have 20% or less, and the third nucleon has most of the transferred energy. These fast pp and pn pairs are back to back with little momentum along the three-momentum transfer, indicating that they are spectators. Calculations by Sargsian and by Laget also indicate that we have measured distorted two-nucleon momentum distributions by striking one nucleon and detecting the spectator correlated pair. PMID:14995301

  20. Diversity of fragment sizes in multifragmentation of gold nuclei induced by relativistic {sup 3}He ions

    Energy Technology Data Exchange (ETDEWEB)

    Brzychczyk, J.; Pollacco, E.C.; Volant, C.; Legrain, R. [DAPNIA/SPhN CEA/Saclay, F-91191 Gif-sur-Yvette Cedex (France); Lacroix, D. [GANIL, BP5027 F-14021 Caen Cedex (France); Kwiatkowski, K.; Bracken, D.S.; Morley, K.B.; Renshaw Foxford, E.; Viola, V.E.; Yoder, N.R. [Departments of Chemistry and Physics and Indiana University Cyclotron Facility, Indiana University, Bloomington, Indiana 47405 (United States); Cugnon, J. [Universite de Liege, Institut de Physique, B-4000 Liege 1 (Belgium); Korteling, R.G. [Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, (Canada) V5A S16; Breuer, H. [Department of Physics, University of Maryland, College Park, Maryland 20742 (United States)

    1998-09-01

    The charge-moment technique has been used to study the fragment charge distribution for the {sup 3}He(4.8thinspGeV)+{sup 197}Au reaction. A large variety of fragment charges characterized by a relative variance {approximately}2.3, is observed for excitation energies around 5.5 MeV/nucleon. Similar signals related to a phase transition are predicted by the percolation model and the statistical multifragmentation model. Effects of detector acceptance and contribution from fission are discussed. {copyright} {ital 1998} {ital The American Physical Society}

  1. Diversity of fragment sizes in multifragmentation of gold nuclei induced by relativistic 3He ions

    International Nuclear Information System (INIS)

    The charge-moment technique has been used to study the fragment charge distribution for the 3He(4.8thinspGeV)+197Au reaction. A large variety of fragment charges characterized by a relative variance ∼2.3, is observed for excitation energies around 5.5 MeV/nucleon. Similar signals related to a phase transition are predicted by the percolation model and the statistical multifragmentation model. Effects of detector acceptance and contribution from fission are discussed. copyright 1998 The American Physical Society

  2. Charge symmetry breaking effect for 3H and 3He within s-wave approach

    Science.gov (United States)

    Filikhin, I.; Suslov, V. M.; Vlahovic, B.

    2016-06-01

    Three-nucleon systems are considered assuming the neutrons and protons to be distinguishable particles. The configuration space Faddeev equations are exploited to calculate ground state energies of 3H and 3He nuclei within an s-wave approach applying the Malfliet-Tjon, Tamagaki G3RS and Afnan-Tang ATS3 NN potentials. We modify the potentials by scaling strength parameters to define nn, pp and np singlet components. The scaling parameters are fixed to reproduce experimental scattering lengths. The charge symmetry breaking energy is numerically evaluated. The relation between nn, pp and np singlet potentials is discussed.

  3. Evidence for soft vortex cores in 3He-B at high magnetic fields

    International Nuclear Information System (INIS)

    Negative ion mobility in rotating 3He-B at magnetic fields H ≅ 0.1 T has been measured along the common direction of H and the rotation axis Ω. When Ω > 0, we observed an increase of mobility, which originates from a reorientation of the anisotropic energy gap. The increase can be understood quantitatively only if soft vortex cores, predicted by Sonin, are assumed. Their size was found to be on the order of the magnetic Healing length ξH

  4. Trapping of ultra cold atoms in a 3He/4He dilution refrigerator

    CERN Document Server

    Jessen, F; Bell, S C; Vergien, P; Hattermann, H; Weiss, P; Rudolph, M; Reinschmidt, M; Meyer, K; Gaber, T; Cano, D; Guenther, A; Bernon, S; Koelle, D; Kleiner, R; Fortagh, J

    2013-01-01

    We describe the preparation of ultra cold atomic clouds in a dilution refrigerator. The closed cycle 3He/4He cryostat was custom made to provide optical access for laser cooling, optical manipulation and detection of atoms. We show that the cryostat meets the requirements for cold atom experiments, specifically in terms of operating a magneto-optical trap, magnetic traps and magnetic transport under ultra high vacuum conditions. The presented system is a step towards the creation of a quantum hybrid system combining ultra cold atoms and solid state quantum devices.

  5. Investigation of the exclusive 3He(e,e' pn)1H reaction.

    Science.gov (United States)

    Middleton, D G; Annand, J R M; Antelo, M Ases; Ayerbe, C; Barneo, P; Baumann, D; Bermuth, J; Bernauer, J; Blok, H P; Böhm, R; Bosnar, D; Ding, M; Distler, M O; Friedrich, J; Llongo, J García; Glazier, D I; Golak, J; Glöckle, W; Grabmayr, P; Hehl, T; Heim, J; Hesselink, W H A; Jans, E; Kamada, H; Mañas, G Jover; Kohl, M; Lapikás, L; MacGregor, I J D; Martin, I; McGeorge, J C; Merkel, H; Merle, P; Monstad, K; Moschini, F; Müller, U; Nogga, A; Pérez-Benito, R; Pospischil, Th; Potokar, M; Rosner, G; Seimetz, M; Skibiński, R; de Vries, H; Walcher, Th; Watts, D P; Weinriefer, M; Weiss, M; Witała, H; Zihlmann, B

    2009-10-01

    Cross sections for the 3He(e,e' pn)1H reaction were measured for the first time at energy transfers of 220 and 270 MeV for several momentum transfers ranging from 300 to 450 MeV/c. Cross sections are presented as a function of the momentum of the recoil proton and the momentum transfer. Continuum Faddeev calculations using the Argonne V18 and Bonn-B nucleon-nucleon potentials overestimate the measured cross sections by a factor 5 at low recoil proton momentum with the discrepancy becoming smaller at higher recoil proton momentum. PMID:19905628

  6. Investigation of the Exclusive ^{3}He(e,e'pn)p Reaction

    CERN Document Server

    Middleton, D G; Antelo, M Ases; Ayerbe, C; Barneo, P; Baumann, D; Bermuth, J; Bernauer, J; Blok, H P; Bosnar, D; Böhm, R; Ding, M; Distler, M O; Friedrich, J; Llongo, J García; Glazier, D I; Golak, J; Glöckle, W; Grabmayr, P; Hehl, T; Heim, J; Hesselink, W H A; Jans, E; Kamada, H; Mañas, G Jover; Köhl, M; Lapikás, L; MacGregor, I J D; Martin, I; McGeorge, J C; Merkel, H; Merle, P; Monstad, K; Moschini, F; Müller, U; Nogga, A; Benito, R Pérez; Pospischil, Th; Potokar, M; Rosner, G; Seimetz, M; Skibiński, R; De Vries, H; Walcher, Th; Watts, D P; Weinriefer, M; Weiss, M; Witała, H; Zihlmann, B

    2009-01-01

    Cross sections for the ^{3}He(e,e'pn)p reaction were measured for the first time at energy transfers of 220 and 270 MeV for several momentum transfers ranging from 300 to 450 MeV/c. Cross sections are presented as a function of the momentum of the recoil proton and the momentum transfer. Continuum Faddeev calculations using the Argonne V18 and Bonn-B nucleon-nucleon potentials overestimate the measured cross sections by a factor 5 at low recoil proton momentum with the discrepancy becoming much smaller at higher recoil momentum.

  7. Lowest vibrational states of 4He3He+: Non-Born-Oppenheimer calculations

    International Nuclear Information System (INIS)

    Very accurate quantum mechanical calculations of the first five vibrational states of the 4He3He+ molecular ion are reported. The calculations have been performed explicitly including the coupling of the electronic and nuclear motions [i.e., without assuming the Born-Oppenheimer (BO) approximation]. The nonrelativistic non-BO wave functions were used to calculate the α2 relativistic mass velocity, Darwin, and spin-spin interaction corrections. For the lowest vibrational transition, whose experimental energy is established with high precision, the calculated and the experimental results differ by only 0.16 cm-1

  8. Low-density phases of 3He monolayers adsorbed on graphite

    Science.gov (United States)

    Ruggeri, Michele; Vitali, Ettore; Galli, Davide Emilio; Boninsegni, Massimo; Moroni, Saverio

    2016-03-01

    Quantum Monte Carlo simulations at zero temperature of a 3He monolayer adsorbed on graphite, either clean or preplated with 4He, unexpectedly point to a gas-liquid phase transition at a very low areal density of the order of 0.01 Å-2 . This result stems from an essentially unbiased calculation of the ground-state energy for an infinite, defect-free substrate, which interacts with He atoms via a realistic potential, whereas the interaction between two He atoms includes two- and three-body terms. The sensitivity of the gas-liquid coexistence region on the model Hamiltonian employed is discussed.

  9. Development of a 3He nuclear spin flip system on an in-situ SEOP 3He spin filter and demonstration for a neutron reflectometer and magnetic imaging technique

    Science.gov (United States)

    Hayashida, H.; Oku, T.; Kira, H.; Sakai, K.; Hiroi, K.; Ino, T.; Shinohara, T.; Imagawa, T.; Ohkawara, M.; Ohoyama, K.; Kakurai, K.; Takeda, M.; Yamazaki, D.; Oikawa, K.; Harada, M.; Miyata, N.; Akutsu, K.; Mizusawa, M.; Parker, J. D.; Matsumoto, Y.; Zhang, S.; Suzuki, J.; Soyama, K.; Aizawa, K.; Arai, M.

    2016-04-01

    We have been developing a 3He neutron spin filter (NSF) using the spin exchange optical pumping (SEOP) technique. The 3He NSF provides a high-energy polarized neutron beam with large beam size. Moreover the 3He NSF can work as a π-flipper for a polarized neutron beam by flipping the 3He nuclear spin using a nuclear magnetic resonance (NMR) technique. For NMR with the in-situ SEOP technique, the polarization of the laser must be reversed simultaneously because a non-reversed laser reduces the polarization of the spin-flipped 3He. To change the polarity of the laser, a half-wavelength plate was installed. The rotation angle of the half-wavelength plate was optimized, and a polarization of 97% was obtained for the circularly polarized laser. The 3He polarization reached 70% and was stable over one week. A demonstration of the 3He nuclear spin flip system was performed at the polarized neutron reflectometer SHARAKU (BL17) and NOBORU (BL10) at J-PARC. Off-specular measurement from a magnetic Fe/Cr thin film and magnetic imaging of a magnetic steel sheet were performed at BL17 and BL10, respectively.

  10. Double antikaonic nuclear clusters in antiproton-{sup 3}He annihilation at J-PARC

    Energy Technology Data Exchange (ETDEWEB)

    Sakuma, Fuminori, E-mail: sakuma@ribf.riken.jp [RIKEN, RIKEN Nishina Center (Japan); Curceanu, Catalina [Laboratori Nazionali di Frascati dell' INFN (Italy); Iwasaki, Masahiko [RIKEN, RIKEN Nishina Center (Japan); Kienle, Paul [Technische Universiat Munchen (Germany); Ohnishi, Hiroaki [RIKEN, RIKEN Nishina Center (Japan); Tokuda, Makoto [The University of Tokyo, Department of Physics (Japan); Tsukada, Kyo [Tohoku University, Department of Physics (Japan); Widmann, Eberhard [Stefan-Meyer-Institut fuer Subatomare Physik (Austria); Yamazaki, Toshimitsu [RIKEN, RIKEN Nishina Center (Japan); Zmeskal, Johannes [Stefan-Meyer-Institut fuer Subatomare Physik (Austria)

    2012-12-15

    We search for double anti-kaon nuclear bound states in the p-bar annihilation reaction in {sup 3}He nuclei at rest. In view of the strongly attractive K-bar N interaction, the existence of nuclear clusters with more than one K{sup }- has been predicted theoretically. The double anti-kaon production in elementary antiproton annihilation at rest is forbidden because of the negative Q-value; however, a double anti-kaon nuclear bound state, such as K{sup }- K{sup }- pp, with deep binding energy would enable double anti-kaon production in the nuclei. In order to investigate the K{sup }- K{sup }- pp production in the p-bar + {sup 3}He {yields} K{sup +} + K{sup 0} + X (X = K{sup -} K{sup -} pp) channel, the produced K{sup }- K{sup }- pp cluster is identified both using missing mass spectroscopy via the K{sup + }K{sup 0} channel with a {Lambda}-tag, and invariant mass analysis of the expected decay particles from the K{sup }- K{sup }- pp cluster such as {Lambda}{Lambda}. We propose to perform the experiment at the existing K1.8BR beam line at J-PARC with the E15 spectrometer.

  11. The nuclear reaction n + 3He -> 1H + 3H as proximity reaction

    International Nuclear Information System (INIS)

    The present thesis tries to give by means of the nuclear reaction n + 3He -> 1H + 3H as proximity reaction on the three-particle system 3He + 9Be -> 1H + 3H + 8Be an experimental verification to the second term of a multiple scattering series. The study of these rescattering effects is of great interest for the present theory of the final-state interaction. At three incident energies (7.08 MeV, 8.98 MeV, and 6.37 MeV) to detector telescopes identify the exit channel of the three-particle system in list-mode coincidence experiments according to protons and tritons. Peaks on the kinematical curves occur. The detailed study of their kinematic behaviour allows to exclude the inconcurrence to the proximity reaction lying cascade decays via intermediate states in 4He, 9B, and 11B. Regarding the Coulomb interaction the experimental results can be also explained in the sense of the classical kinematics by the proximity model. (orig.)

  12. Study of anti-deuterons, anti-tritons and anti-{sup 3}He at Belle

    Energy Technology Data Exchange (ETDEWEB)

    Kuenze, Stephanie; Galuska, Martin; Gessler, Thomas; Kuehn, Wolfgang; Lange, Jens Soeren; Muenchow, David; Semmler, Diego; Spruck, Bjoern; Ullrich, Matthias; Werner, Marcel [2. Physikalisches Institut, Universitaet Giessen (Germany)

    2010-07-01

    Events of the type e{sup +}e{sup -}{yields} anti d+X, anti t+X, anti-{sup 3}He+X, are rare events in e{sup +}e{sup -} collisions as they require the production of several anti-quarks together with their corresponding quarks (6+6 in the deuteron case, 9+9 for triton and {sup 3}He). In addition, in order to form a bound state, the anti-quarks must be close in phasespace, so that coalescence (i.e. overlap of the wave functions) can be applied. Preliminary results from Belle at {radical}(s){approx_equal}10.6 GeV with a data set of 589fb{sup -1}, using dE/dx in the Belle drift chamber for particle identification, are presented. The momentum distribution of the anti-nuclei can be compared to a fireball model. Preliminary results of the search for anti-{sup 4}He are also presented.

  13. Vortices with half-integer number of circulation quanta in superfluid 3He-A

    International Nuclear Information System (INIS)

    A method is proposed for the experimental observation of the exotic vortices with a half-integer number of superfluid velocity circulation quanta in rotating 3He-A. The existence of such vortices in 3He-A is possible due to the presence of discrete combined symmetry (gauge transformation+spin rotation). This symmetry couples in a nontrivial manner the superfluid and magnetic properties of the liquid and gives rise to the hybrid of the vortex and disclination in the field of the magnetic anisotropy vector. In a free geometry such vortices are energetically not advantageous due to the spin-orbit (dipole) energy since they are termination lines of the topological solitons. For a parallel-plane geometry with distances between the planes which are smaller than the dipole lenght and in the presence of a sufficiently strong magnetic field normal to the plates the dipole energy is neutralized, and the vortices with half-integer circulation may compete successfully with other types of vortices. Vortices with a half-integer number of quanta should lead to a characteristic behaviour of the NMR signal, and on this basis they may distinguished from singular vortices with a single circulation quantum and from nonsingular vortices with two quanta

  14. Textures of Superfluid 3He-B in Applied Flow and Comparison with Hydrostatic Theory

    CERN Document Server

    de Graaf, R; Hosio, J J; Heikkinen, P J; Krusius, M

    2011-01-01

    Measurements of the order parameter texture of rotating superfluid 3He-B have been performed as a function of the applied azimuthal counterflow velocity down to temperatures of 0.2Tc. The results are compared to the hydrostatic theory of 3He-B. Good agreement is found at all measured temperatures and rotation velocities when the flow anisotropy contribution to the textural free energy is adjusted. This gives a superfluid energy gap Delta(T) which agrees with that measured by Todoshchenko et al., with Delta(0)=1.97kBTc at 29.0 bar. The B-phase susceptibility, longitudinal resonance frequency, and textural phase transition have been extracted from the measurements as a function of temperature and azimuthal counterflow velocity. Owing to decreasing absorption intensities the present measuring method, based on the line shape analysis of the NMR spectrum, loses its sensitivity with decreasing temperature. However, we find that in practice the measurement of vortex numbers and counterflow velocities is still feasib...

  15. The 31P(3He,d)32S reactions at 25MeV

    International Nuclear Information System (INIS)

    The 31P(3He,d)32S reaction was investigated at 25 MeV incident energy. One hundred and eleven levels up to an excitation energy of 12.5 MeV were observed using a split-pole magnetic spectrograph. The experimental angular distributions were analyzed with the distorted-wave Born approximation. The optical model parameters used in the DWBA calculations were obtained from a fit to elastic 3He scattering data taken on 31P at 25 MeV. Gamov functions were used as form factors for the transfered proton in the case of unbound states. Values of the transfered orbital angular momenta l and spectroscopic strengths were obtained for sixty levels, with many odd-parity levels being observed above 9 MeV excitation. Spin and parity assignments were made upon the basis of the l-values obtained from the shapes of the angular distributions and upon comparison with the results of other reactions. Isospin assignments were made by comparison with 32P levels. Except for the lsub(P)=1, T=0 transfers, most of the observed spectroscopic strength is concentrated into a few levels. The existence of a T-mixed doublet of levels, Jsup(π)=1-, is suggested in the 11 MeV region of excitation. The excitation energies and spectroscopic strengths are compared with results of a recent shell-model calculation

  16. Light Higgs channel of the resonant decay of magnon condensate in superfluid 3He-B

    Science.gov (United States)

    Zavjalov, V. V.; Autti, S.; Eltsov, V. B.; Heikkinen, P. J.; Volovik, G. E.

    2016-01-01

    In superfluids the order parameter, which describes spontaneous symmetry breaking, is an analogue of the Higgs field in the Standard Model of particle physics. Oscillations of the field amplitude are massive Higgs bosons, while oscillations of the orientation are massless Nambu-Goldstone bosons. The 125 GeV Higgs boson, discovered at Large Hadron Collider, is light compared with electroweak energy scale. Here, we show that such light Higgs exists in superfluid 3He-B, where one of three Nambu-Goldstone spin-wave modes acquires small mass due to the spin–orbit interaction. Other modes become optical and acoustic magnons. We observe parametric decay of Bose-Einstein condensate of optical magnons to light Higgs modes and decay of optical to acoustic magnons. Formation of a light Higgs from a Nambu-Goldstone mode observed in 3He-B opens a possibility that such scenario can be realized in other systems, where violation of some hidden symmetry is possible, including the Standard Model. PMID:26743951

  17. (83)Kr nuclear magnetic moment in terms of that of (3)He.

    Science.gov (United States)

    Makulski, Włodzimierz

    2014-08-01

    High resolution NMR spectroscopy was applied to precisely determine the (83)Kr nuclear magnetic dipole moment on the basis of new results available for nuclear magnetic shielding in krypton and helium-3 atoms. Small amounts of (3)He as the solutes and (83)Kr as the buffer gas were observed in (3)He and (83)Kr NMR spectra at the constant external field, B0 = 11.7578 T. In each case, the resonance frequencies (ν(He) and ν(Kr)) were linearly dependent on the density of gaseous solvent. The extrapolation of experimental points to the zero density of gaseous krypton allowed for the evaluation of both resonance frequencies free from intermolecular interactions. By combining these measurements with the recommended (83)Kr chemical shielding value, the nuclear magnetic moment could be determined with much better precision than ever before, μ((83)Kr) = -0.9707297(32)μN, with the improvement due to the greater accuracy of the spectral data.

  18. Neutron spectrometry using artificial neural networks for a Bonner sphere spectrometer with a 3He detector

    International Nuclear Information System (INIS)

    Neutron spectra unfolding and dose equivalent calculation are complicated tasks in radiation protection, are highly dependent of the neutron energy, and a precise knowledge on neutron spectrometry is essential for all dosimetry-related studies as well as many nuclear physics experiments. In previous works have been reported neutron spectrometry and dosimetry results, by using the artificial neural networks (Ann) technology as alternative solution, starting from the count rates of a Bonner spheres system with a 6LiI(Eu) thermal neutrons detector, 7 polyethylene spheres and the UTA4 response matrix with 31 energy bins. In this work, an Ann was designed and optimized by using the RDAnn methodology for the Bonner spheres system used at CIEMAT Spain, which is composed of a 3He neutron detector, 12 moderator spheres and a response matrix for 72 energy bins. For the Ann design process a neutrons spectra catalogue compiled by the IAEA was used. From this compilation, the neutrons spectra were converted from lethargy to energy spectra. Then, the resulting energy fluence spectra were re-bin ned by using the MCNP code to the corresponding energy bins of the 3He response matrix before mentioned. With the response matrix and the re-bin ned spectra the counts rate of the Bonner spheres system were calculated and the resulting re-bin ned neutrons spectra and calculated counts rate were used as the Ann training data set. (Author)

  19. Light Higgs channel of the resonant decay of magnon condensate in superfluid (3)He-B.

    Science.gov (United States)

    Zavjalov, V V; Autti, S; Eltsov, V B; Heikkinen, P J; Volovik, G E

    2016-01-01

    In superfluids the order parameter, which describes spontaneous symmetry breaking, is an analogue of the Higgs field in the Standard Model of particle physics. Oscillations of the field amplitude are massive Higgs bosons, while oscillations of the orientation are massless Nambu-Goldstone bosons. The 125 GeV Higgs boson, discovered at Large Hadron Collider, is light compared with electroweak energy scale. Here, we show that such light Higgs exists in superfluid (3)He-B, where one of three Nambu-Goldstone spin-wave modes acquires small mass due to the spin-orbit interaction. Other modes become optical and acoustic magnons. We observe parametric decay of Bose-Einstein condensate of optical magnons to light Higgs modes and decay of optical to acoustic magnons. Formation of a light Higgs from a Nambu-Goldstone mode observed in (3)He-B opens a possibility that such scenario can be realized in other systems, where violation of some hidden symmetry is possible, including the Standard Model. PMID:26743951

  20. Ultrasonic Spectroscopy in Liquid ^3He in 98% Porosity Aerogel by Direct Propagation

    Science.gov (United States)

    Choi, H. C.; Masuhara, N.; Park, J.-H.; Meisel, M. W.; Lee, Y.; Mulders, N.

    2006-03-01

    Systematic investigations on the effect of static disorder on p-wave superfluid ^3He have been made possible by utilizing its unique structure of high porosity silica aerogel. For the past 10 years, a burst of experimental effort revealed that three distinct superfluid phases exist in the P-H-T phase diagram of the ^3He/98% aerogel system. These three phases are conveniently named the A-, B-, and A1-phases as in the bulk, although only spin structures of the superfluid phases have been identified. In particular, the verdict on the so called A-phase is by no means conclusive. As has been the case in the bulk, for a clear identification of the order parameter structure, both spin and orbital components need to be examined. We report our preliminary results of sound propagation in an attempt to directly investigate the orbital structure of the superfluid phases in 98% aerogel using a pulsed ultrasound spectroscopic technique. Preliminary data for the transmission and the surface impedance will be presented.

  1. Measurement of the excitation function of {sup 65}Cu({sup 3}He,2n){sup 66}Ga; Medida da funcao excitacao da reacao {sup 65} Cu({sup 3} He,2n) {sup 66} Ga

    Energy Technology Data Exchange (ETDEWEB)

    Bastos, M.A.V.; Vinagre Filho, U.M.; Costa, V.L. da [Instituto de Engenharia Nuclear (IEN), Rio de Janeiro, RJ (Brazil)

    1996-07-01

    The excitation function of the {sup 65} Cu({sup 3} He,2n) {sup 66} Ga reaction was measured. It was performed by irradiation of several stacks of two copper foils with {sup 3} He until 36 MeV from the cyclotron CV-28 of IEN. The initial energy of {sup 3} He beam was measured by spectrometry of charged particles with Si (au) detector, placed at 90 deg C respecting to the incident beam. The activities was measured by gamma rays spectrometry using HPGe detector. The results are compared with others found in the literature. (author)

  2. Studies on the atomic capture of stopped negative pions in binary mixtures of /sup 3/He with other gases

    Energy Technology Data Exchange (ETDEWEB)

    Bannikov, A.V.; Levay, B.; Petrukhin, V.I.; Vasilyev, V.A. (Joint Inst. for Nuclear Research, Dubna (USSR)); Kochenda, L.M.; Markov, A.A.; Medvedev, V.I.; Sokolov, G.L.; Strakovsky, I.I. (Leningrad Nuclear Physics Inst., Gatchina (USSR)); Horvath, D. (Hungarian Academy of Sciences, Budapest. Central Research Inst. for Physics)

    1983-07-25

    Systematic experimental study has been carried out on the atomic capture of negative pions by /sup 3/He in binary gas mixtures of /sup 3/He + Z, where Z is Ne, Ar, Kr, Xe, N/sub 2/, O/sub 2/, CO/sub 2/ and SF/sub 6/. The results are analysed in the framework of a phenomenological model. It is shown that there is no pion transfer from the /sup 3/He..pi../sup -/ mesic atoms to the heavier Z-atoms. The probabilities of pion capture in the various atoms of the mixtures are found to be proportional to the atomic concentraions, thereby excluding the possibility of a concentration dependence in the atomic capture ratio A(Z//sup 3/He). In contradiction to previous assumptions the probability of pion capture into an atomic orbit is not proportional to the stopping power of the components of the mixture. The atomic capture ratio of pions in a /sup 3/He + /sup 4/He mixture is A(/sup 4/He//sup 3/He) = 0.75 +- 0.13, which might be the indication of an isotopic effect. The branching ratio for the charge-exchange reaction at rest ..pi../sup -/ + /sup 3/He -> ..pi../sup 0/ + /sup 3/H) is found to be 0.128 +- 0.012.

  3. Studies on the atomic capture of stopped negative pions in binary mixtures of /sup 3/He with other gases

    Energy Technology Data Exchange (ETDEWEB)

    Bannikov, A.V.; Levay, B.; Petrukhin, V.I.; Vasilyev, V.A. (Joint Inst. for Nuclear Research, Dubna (USSR)); Kochenda, L.M.; Markov, A.A.; Medvedev, V.I.; Sokolov, G.L.; Strakovsky, I.I. (Leningrad Nuclear Physics Inst., Gatchina (USSR)); Horvath, D. (Hungarian Academy of Sciences, Budapest. Central Research Inst. for Physics)

    1983-07-25

    Systematic experimental study has been carried out on the atomic capture of negative pions by /sup 3/He in binary gas mixtures of /sup 3/He + Z, where Z is Ne, Ar, Kr, Xe, N/sub 2/, O/sub 2/, CO/sub 2/ and SF/sub 6/. The results are analyzed in the framework of a phenomenological model. It is shown that there is no pion transfer from the /sup 3/He..pi../sup -/ mesic atoms to the heavier Z-atoms. The probabilities of pion capture in the various atoms of the mixtures are found to be proportional to the atomic concentraions, thereby excluding the possibility of a concentration dependence in the atomic capture ratio A(Z//sup 3/He). In contradiction to previous assumptions the probability of pion capture into an atomic orbit is not proportional to the stopping power of the components of the mixture. The atomic capture ratio of pions in a /sup 3/He + /sup 4/He mixture is A(/sup 4/He//sup 3/He) = 0.75 +- 0.13, which might be the indication of an isotopic effect. The branching ratio for the charge-exchange reaction at rest ..pi../sup -/ + /sup 3/He -> ..pi../sup 0/ + /sup 3/H is found to be 0.128 +- 0.012.

  4. Correlation of the apparent diffusion coefficient (ADC with the standardized uptake value (SUV in lymph node metastases of non-small cell lung cancer (NSCLC patients using hybrid 18F-FDG PET/MRI.

    Directory of Open Access Journals (Sweden)

    Benedikt Michael Schaarschmidt

    Full Text Available To compare the apparent diffusion coefficient (ADC in lymph node metastases of non-small cell lung cancer (NSCLC patients with standardized uptake values (SUV derived from combined 18F-fluoro-deoxy-glucose-positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI.38 patients with histopathologically proven NSCLC (mean age 60.1 ± 9.5 y received whole-body PET/CT (Siemens mCT™ 60 min after injection of a mean dose of 280 ± 50 MBq 18F-FDG and subsequent PET/MRI (mean time after tracer injection: 139 ± 26 min, Siemens Biograph mMR. During PET acquisition, simultaneous diffusion-weighted imaging (DWI, b values: 0, 500, 1000 s/mm² was performed. A maximum of 10 lymph nodes per patient suspicious for malignancy were analyzed. Regions of interest (ROI were drawn covering the entire lymph node on the attenuation-corrected PET-image and the monoexponential ADC-map. According to histopathology or radiological follow-up, lymph nodes were classified as benign or malignant. Pearson's correlation coefficients were calculated for all lymph node metastases correlating SUVmax and SUVmean with ADCmean.A total of 146 suspicious lymph nodes were found in 25 patients. One hundred lymph nodes were eligible for final analysis. Ninety-one lymph nodes were classified as malignant and 9 as benign according to the reference standard. In malignant lesions, mean SUVmax was 9.1 ± 3.8 and mean SUVmean was 6.0 ± 2.5 while mean ADCmean was 877.0 ± 128.6 x10(-5 mm²/s in PET/MRI. For all malignant lymph nodes, a weak, inverse correlation between SUVmax and ADCmean as well as SUVmean and ADCmean (r = -0.30, p<0.05 and r = -0.36, p<0.05 existed.The present data show a weak inverse correlation between increased glucose-metabolism and cellularity in lymph node metastases of NSCLC patients. 18F-FDG-PET and DWI thus may offer complementary information for the evaluation of treatment response in lymph node metastases of NSCLC.

  5. Reaction mechanism and characteristics of T_{20} in d + ^3He backward elastic scattering at intermediate energies

    OpenAIRE

    Tanifuji, M.; Ishikawa, S.; Iseri, Y.; Uesaka, T.; Sakamoto, N; Satou, Y.; Itoh, K.; Sakai, H.; Tamii, A.; Ohnishi, T.; Sekiguchi, K.; Yako, K.; Sakoda, S.; Okamura, H.; Suda, K.

    1999-01-01

    For backward elastic scattering of deuterons by ^3He, cross sections \\sigma and tensor analyzing power T_{20} are measured at E_d=140-270 MeV. The data are analyzed by the PWIA and by the general formula which includes virtual excitations of other channels, with the assumption of the proton transfer from ^3He to the deuteron. Using ^3He wave functions calculated by the Faddeev equation, the PWIA describes global features of the experimental data, while the virtual excitation effects are impor...

  6. Oblique ion acoustic wave instabilities in a multi-ion plasma and 3He-rich events

    International Nuclear Information System (INIS)

    Oblique ion acoustic waves in a current-carrying, magnetized plasma are investigated. For a multi-ion plasma whose dominant components are hydrogen and helium, it is found that for some plasma parameters oblique ion acoustic waves can have positive growth rates at frequencies ω ≅ Ω3He (3He cyclotron frequency) and, at the same time, negative growth rates at ω ≅ Ω4He, It is then suggested that these waves can play an essential role in the 3He-rich solar flares. (author)

  7. Near Threshold Two Meson Production with the pd {yields} {sup 3}He{pi}{sup +}{pi}{sup {minus}} and pd {yields} {sup 3}HeK{sup +}K{sup {minus}} Reactions

    Energy Technology Data Exchange (ETDEWEB)

    COSY-MOMO Collaboration

    2000-12-31

    Near-threshold two-meson production via the reactions pd {yields} {sup 3}He{pi}{sup +}{pi}{sup {minus}} and pd {yields} {sup 3}HeK{sup +}K{sup {minus}} was measured kinematically complete with the MOMO experiment at COSY. The obtained two-pion variant mass spectra and angular distributions depict a remarkable deviation from phase space. The two-kaon data are consistent with phase space topped by a clear signal of the {phi} meson.

  8. Construction of a $^3$He magnetic force microscope with a vector magnet

    CERN Document Server

    Yang, Jinho; Kim, Yun Won; Shin, Dongwoo; Jeong, Juyoung; Wulferding, Dirk; Yeom, Han Woong; Kim, Jeehoon

    2016-01-01

    We constructed a $^3$He magnetic force microscope operating at the base temperature of 300 mK under a vector magnetic field of 2-2-9 T in the $x-y-z$ direction. Fiber optic interferometry as a detection scheme is employed in which two home-built fiber walkers are used for the alignment between the cantilever and the optical fiber. The noise level of the laser interferometer is close to its thermodynamic limit. The capabilities of the sub-Kelvin and vector field are demonstrated by imaging the coexistence of magnetism and superconductivity in a ferromagnetic superconductor (ErNi$_2$B$_2$C) at $T$=500 mK and by probing a dipole shape of a single Abrikosov vortex with an in-plane tip magnetization.

  9. On Larkin-Imry-Ma State of 3He-A in Aerogel

    CERN Document Server

    Volovik, G E

    2007-01-01

    Superfluid 3He-A shares the properties of spin nematic and chiral orbital ferromagnet. Its order parameter is characterized by two vectors d and l. This doubly anisotropic superfluid, when it is confined in aerogel, represents the most interesting example of a system with continuous symmetry in the presence of random anisotropy disorder. We discuss the Larkin-Imry-Ma state, which is characterized by the short-range orientational order of the vector l, while the long-range orientational order is destroyed by the collective action of the randomly oriented aerogel strings. On the other hand, sufficiently large regular anisotropy produced either by the deformation of the aerogel or by applied superflow destroys the Larkin-Imry-Ma effect leading to the uniform orientation of the vector l. This interplay of regular and random anisotropy allows us to study many different effects.

  10. A two-stage 3He- 4He fridge for bolometric photometry

    Science.gov (United States)

    Maiani, T.; de Bernardis, P.; De Petris, M.; Granata, S.; Masi, S.; Orlando, A.; Aquilini, E.; Cardoni, P.; Martinis, L.; Scaramuzzi, F.

    1999-09-01

    We describe the design, construction and performance of a double stage 3He- 4He refrigerator, built to cool down a multiband bolometric photometer at the MITO telescope. The fridge was optimized to work without external pumps, with the main cryostat providing a 4.2 K thermostat at sea level and a 4.0 K one at high mountain pressure conditions. The measured ultimate temperature of the fridge is 290 mK, with a hold time of 81 h. The external heat input on the cold flange is ˜35 μW, with the main bath at 4.0 K. The recycle time is 8 h with a heat input on the thermostat during recycling of ˜6800 J. The cryostat can operate without any relevant changes to performance tilted down to 50° from the vertical position, as needed at the telescope focal plane.

  11. Inclusive $^{2}H(^{3}He,t)$ reaction at 2 GeV

    CERN Document Server

    Ramstein, B; Bachelier, D; Berquist, I; Boivin, M; Boyard, J L; Brockstedt, A; Carlén, L; Dahl, R; Ekström, R E; Ellegaard, C; Gaarde, C; Hennino, T; Jourdain, J C; Goodman, C; Larsen, J S; Radvanyi, P; Roy-Stephan, M

    1999-01-01

    The inclusive 2H(3He,t) reaction has been studied at 2 GeV for energy transfers up to 500 MeV and scattering angles from 0.25 up to 4 degrees. Data are well reproduced by a model based on a coupled-channel approach for describing the NN and N Delta systems. The effect of final state interaction is important in the low energy part of the spectra. In the delta region, the cross-section is very sensitive to the effects of Delta-N interaction and Delta N - NN process. The latter has also a large influence well below the pion threshold. The calculation underestimates the experimental cross-section between the quasi-elastic and the delta peaks; this is possibly due to projectile excitation or purely mesonic exchange currents.

  12. The ( sup 3 He,t) reaction at intermediate energies; Spin-isospin multipole transitions

    Energy Technology Data Exchange (ETDEWEB)

    Brockstedt, A.; Bergquist, I.; Carlen, L.; Ekstroem, L.P.; Jakobsson, B. (Lund Univ. (Sweden). Inst. of Physics); Ellegaard, C.; Gaarde, C.; Larsen, J.S. (Niels Bohr Inst., Copenhagen (Denmark)); Goodman, C. (Indiana Univ., Bloomington, IN (USA)); Bedjidian, M.; Contardo, D.; Grossiord, J.Y.; Guichard, A.; Pizzi, J.R. (Lyon Univ., 69 - Villeurbanne (France). Inst. de Physique Nucleaire); Bachelier, D.; Boyard, J.L.; Hennino, T.; Jourdain, J.C.; Roy-Stephan, M. (Institut de Physique Nucleaire, 91 - Orsay (France)); Boivin, M.; Hasegawa, T.; Radvanyi, P. (Laboratoire National Saturne, 91 - Gif-sur-Yvette (France))

    1991-08-01

    Data for the ({sup 3}He, t) reaction at 900 MeV and 2 GeV on the targets {sup 26}Mg, {sup 40}Ca, {sup 48}Ca, {sup 54}Fe, {sup 90}Zr and {sup 208}Pb are presented. A multipole decomposition for the data at 900 MeV has been made and the different distributions have been analysed. From the L=0 cross section the Gamow-Teller strength distributions are extracted and compared with (p, n) data. The L=1 and 2 distributions are analysed in a schematic model which describes the general systematics fairly well. The spectra at 2 GeV and {Theta}=4deg show for all targets a well-developed quasi-elastic peak. The A-dependence of the cross section is analysed in a simple model. (orig.).

  13. ABC Effect and Resonance Structure in the Double-Pionic Fusion to $^3$He

    CERN Document Server

    Adlarson, P; Bardan, W; Bashkanov, M; Bergmann, F S; Berłowski, M; Bhatt, H; Bondar, A; Büscher, M; Calén, H; Ciepał, I; Clement, H; Coderre, D; Czerwiński, E; Demmich, K; Doroshkevich, E; Engels, R; Erven, A; Erven, W; Eyrich, W; Fedorets, P; Föhl, K; Fransson, K; Goldenbaum, F; Goslawski, P; Goswami, A; Grigoryev, K; Gullström, C --O; Hauenstein, F; Heijkenskjöld, L; Hejny, V; Höistad, B; Hüsken, N; Jarczyk, L; Johansson, T; Kamys, B; Kemmerling, G; Khan, F A; Khoukaz, A; Kirillov, D A; Kistryn, S; Kleines, H; Kłos, B; Krzemień, W; Kulessa, P; Kupść, A; Kuzmin, A; Lalwani, K; Lersch, D; Lorentz, B; Magiera, A; Maier, R; Marciniewski, P; Mariański, B; Mikirtychiants, M; Morsch, H -P; Moskal, P; Ohm, H; Ozerianska, I; del Rio, E Perez; Piskunov, N M; Podkopał, P; Prasuhn, D; Pricking, A; Pszczel, D; Pysz, K; Pyszniak, A; Ritman, J; Roy, A; Rudy, Z; Sawant, S; Schadmand, S; Sefzick, T; Serdyuk, V; Shwartz, B; Siudak, R; Skorodko, T; Skurzok, M; Smyrski, J; Sopov, V; Stassen, R; Stepaniak, J; Stephan, E; Sterzenbach, G; Stockhorst, H; Ströher, H; Szczurek, A; Täschner, A; Trzciński, A; Varma, R; Wagner, G J; Wolke, M; Wrońska, A; Wüstner, P; Wurm, P; Yamamoto, A; Yurev, L; Zabierowski, J; Zieliński, M J; Zink, A; Złomańczuk, J; Żuprański, P; Żurek, M

    2014-01-01

    Exclusive and kinematically complete measurements of the double pionic fusion to $^3$He have been performed in the energy region of the so-called ABC effect, which denotes a pronounced low-mass enhancement in the $\\pi\\pi$-invariant mass spectrum. The experiments were carried out with the WASA detector setup at COSY. Similar to the observations in the basic $pn \\to d \\pi^0\\pi^0$ reaction and in the $dd \\to ^4$He$\\pi^0\\pi^0$ reaction, the data reveal a correlation between the ABC effect and a resonance-like energy dependence in the total cross section. Differential cross sections are well described by the hypothesis of $d^*$ resonance formation during the reaction process in addition to the conventional $t$-channel $\\Delta\\Delta$ mechanism. The deduced $d^*$ resonance width can be understood from collision broadening due to Fermi motion of the nucleons in initial and final nuclei.

  14. Vortex pairs in rotating 3He-A in a tilted magnetic field

    International Nuclear Information System (INIS)

    We extend our analysis of Seppaaumllaauml-Volovik vortices in rotating 3He-A in a high magnetic field to the configuration where the magnetic field is tilted from the rotation axis. We find that the distance between vortices in a vortex pair decreases as the tilting angle increases from 0 to π/2. While the transverse NMR satellite frequency is quite insensitive to tilting except at lower temperature, the intensity of the resonance increases by almost 30% when theta0 = π/2 compared to that for theta0 = 0 (theta0 is the tilting angle) at T/T/sub c/approx. =0.75. This is quite consistent with the recent experimental result of Seppaaumllaauml et al

  15. Tensor Correlations Measured in 3He(e,e'pp)n

    CERN Document Server

    Baghdasaryan, H; Laget, J M; Adhikari, K P; Aghasyan, M; Amarian, M; Anghinolfi, M; Avakian, H; Ball, J; Battaglieri, M; Bedlinskiy, I; Berman, B L; Biselli, A S; Bookwalter, C; Briscoe, W J; Brooks, W K; B?ultmann, S; Burkert, V D; Carman, D S; Crede, V; D'Angelo, A; Daniel, A; Dashyan, N; DeVita, R; DeSanctis, E; Deur, A; Dey, B; Dickson, R; Djalali, C; Dodge, G E; Doughty, D; Dupre, R; Egiyan, H; Alaoui, A El; Fassi, L El; Eugenio, P; Fegan, S; Gabrielyan, M Y; Gilfoyle, G P; Giovanetti, K L; Gohn, W; Gothe, R W; Griffioen, K A; Guidal, M; Guo, L; Gyurjyan, V; Hakobyan, H; Hanretty, C; Hyde, C E; Hicks, K; Holtrop, M; Ilieva, Y; Ireland, D G; Joo, K; Keller, D; Khandaker, M; Khetarpal, P; Kim, A; Kim, W; Klein, A; Klein, F J; Konczykowski, P; Kubarovsky, V; Kuhn, S E; Kuleshov, S V; Kuznetsov, V; Kvaltine, N D; Livingston, K; Lu, H Y; MacGregor, I J D; Markov, N; Mayer, M; McAndrew, J; McKinnon, B; Meyer, C A; Mikhailov, K; Mokeev, V; Moreno, B; Moriya, K; Morrison, B; Moutarde, H; Munevar, E; Nadel-Turonski, P; Nepali, C; Niccolai, S; Niculescu, G; Niculescu, I; Osipenko, M; Ostrovidov, A I; Paremuzyan, R; Park, K; Park, S; Pasyuk, E; Pereira, S Anefalos; Pisano, S; Pogorelko, O; Pozdniakov, S; Price, J W; Procureur, S; Protopopescu, D; Ricco, G; Ripani, M; Rosner, G; Rossi, P; Sabati?e, F; Salgado, C; Schumacher, R A; Seraydaryan, H; Smith, G D; Sober, D I; Sokhan, D; Stepanyan, S S; Stepanyan, S; Stoler, P; Strauch, S; Taiuti, M; Tang, W; Taylor, C E; Tedeschi, D J; Ungaro, M; Vineyard, M F; Voutier, E; Watts, D P; Weygand, D P; Wood, M H; Zhao, B; Zhao, Z W

    2010-01-01

    We have measured the 3He(e,e'pp)n reaction at an incident energy of 4.7 GeV over a wide kinematic range. We identified spectator correlated pp and pn nucleon pairs using kinematic cuts and measured their relative and total momentum distributions. This is the first measurement of the ratio of pp to pn pairs as a function of pair total momentum, $p_{tot}$. For pair relative momenta between 0.3 and 0.5 GeV/c, the ratio is very small at low $p_{tot}$ and rises to approximately 0.5 at large $p_{tot}$. This shows the dominance of tensor over central correlations at this relative momentum.

  16. Determination of the nuclear induced electrical conductivity of 3He for magnetohydrodynamic energy conversion

    International Nuclear Information System (INIS)

    This is the final report for a one-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The continual need for more efficient, high-output energy conversion techniques has renewed interest in nuclear-driven magnetohydrodynamic (MHD) energy conversion. To provide the fundamental knowledge required to evaluate the potential value of this concept, a one-year project aimed at measuring the nuclear-induced electrical conductivity of a 3He/4He gas mixture under thermodynamic conditions consistent with the MHD flow conditions was carried out. The range of bulk gas conditions to be considered were: pressure = 0.1 to 3800 Torr and temperature = 300 to 1500 K. The maximum neutron flux to be considered was 1016/cm2sec. The range of parameters considered surpassed previous experiments in all aspects

  17. Extending the Gutzwiller approximation for liquid {sup 3}He by including intersite correlations

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, D.; Pilgram, S.; Rice, T.M.; Sigrist, M. [Institut fuer Theoretische Physik, ETH Zuerich, 8093 Zuerich (Switzerland)

    2011-08-26

    The simple Gutzwiller approximation, applied to the approach to Mott localization in a half-filled band Hubbard model, gives a remarkably good description of the properties of liquid {sup 3}He as the liquid-solid transition is approached under pressure. The key variable, the density of unbound doubly occupied and empty sites is evaluated keeping only single site correlations. We extend the Gutzwiller approximation to incorporate nearest neighbor correlations. This extension improves the agreement with the experimental evolution of the spin susceptibility and effective mass with pressure, but does not remove the large discrepancy in the compressibility. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Bilayer Hubbard model for 3He: a cluster dynamical mean-field calculation

    International Nuclear Information System (INIS)

    Inspired by recent experiments on bilayer 3He, we consider a bilayer Hubbard model on a triangular lattice. For appropriate model parameters, we observe a band-selective Mott transition at a critical chemical potential, μc, corresponding to the solidification of the fermions in the first layer. The growth of the effective mass on the metallic side (μ c) is cut off by a first order transition in which the first layer fermions drop out of the Luttinger volume and their spin degrees of freedom become locked in a spin singlet state. These results are obtained from a cluster dynamical mean-field calculation on an eight-site cluster with a quantum Monte Carlo cluster solver.

  19. Boost Effects in the (e,e') Transverse Response of 3He

    Science.gov (United States)

    Tomusiak, Edward; Efros, Victor; Leidemann, Winfried; Orlandini, Giuseppina; Yuan, Luping

    2015-10-01

    In an earlier paper Efros et al. investigated frame dependence in calculations of the transverse (e,e') response function of 3He. These calculations were non-relativistic but did incorporate relativistic corrections in the electromagnetic operators. Those corrections, taken from the work of Ritz et al. are of order M-3 and represent kinematical effects. It was found that in the region of the quasi-elastic peak, with one proviso, frame dependence held to a good approximation up to q = 700 MeV/c. The one proviso was that we not include one of the corrections - the so-called ω-dependent term. Although this term vanishes in one of the frames (the ANB frame) the question arises as to whether or not another correction exists which might nearly restore frame independence. This work investigates the possibility that Boost effects may provide an explanation. We report on our progress in this regard.

  20. Precision Hyperfine Structure of 2;^3P State of ^3He with External Magnetic

    Science.gov (United States)

    Wu, Qixue; Drake, G. W. F.

    2007-06-01

    The theory of the Zeeman effect can be used to extrapolate precise measurements for the fine structure or the hyperfine structure to zero-field strength. In the present work, the hyperfine structure of 2;^3P state of ^3He with external magnetic fields is precisely calculated. The values of the fields for 32 crossings and five anticrossings of the magnetic sublevels are theoretically predicted for magnetic field strengths up to 1 Tesla. The results are compared with experimental work. We include the linear terms, diamagnetic terms, and the 2̂ relativistic correction terms in the Zeeman Hamiltonian. All related matrix elements are calculated with high accuracy by the use of double basis set Hylleraas type variational wave functions[1,2].[1] Z. -C. Yan and G.W.F. Drake, Phys. Rev. A 50, R1980 (1994).[2] Q. Wu and G.W.F. Drake, J. Phys. B 40, 393 (2007).

  1. Distinguishing 3He and 4He with the Electron Proton Telescope (EPT) on Solar Orbiter

    Science.gov (United States)

    Boden, S.; Kulkarni, S. R.; Steinhagen, J.; Tammen, J.; Martin-Garcia, C.; Wimmer-Schweingruber, R. F.; Boettcher, S. I.; Seimetz, L.; Ravanbakhsh, A.; Elftmann, R.; Schuster, B.; Kulemzin, A.; Kolbe, S.; Mahesh, Y.; Knieriem, V.; Yu, J.; Kohler, J.; Panitzsch, L.; Terasa, C.; Boehm, E.; Rodriguez-Pacheco, J.; Prieto, M.; Gomez-Herrero, R.

    2015-12-01

    The Electron Proton Telescope (EPT) is one of the sensors of the Energetic Particle Detector (EPD) for the Solar Orbiter mission, which will provide key measurements to address particle acceleration at and near the Sun. The EPD suite consists of four different sensors (STEP, SIS, EPT and HET) which together will resolve the energetic particle spectrum from 2 keV to 20 MeV for electrons, 3 keV to 100 MeV for protons and circa 100 keV/nuc to 100 MeV/nuc for heavier ions.EPT itself is primarily designed to cleanly separate and measure electrons in the energy range from 20 - 400 keV and protons from 20 - 7000 keV. To achieve this, EPT uses two back-to-back solid state detectors with a magnet system to deflect electrons on one side and a Polyimide foil to stop protons below ~400 keV on the other side. The two detectors then serve as each other's anti-coincidence. Additionally this setup also allows us to measure penetrating particles with deposited energies in the 1 MeV to 40 MeV range. Looking at the ratio of deposited energy in the two detectors versus total deposited energy allows us to differentiate between protons and alpha particles. Distinguishing 3He from 4He will be challenging, but possible provided good knowledge of the instrument, high-fidelity modeling and a precise calibration of EPT. Here, we will present feasibility studies leading to a determination of the 3He / 4He ratio with EPT.

  2. Magnetized liquid 3He at finite temperature: A variational calculation approach

    Science.gov (United States)

    Bordbar, Gholam Hossein; Mohammadi Sabet, Mohammad Taghi

    2016-08-01

    Using the spin-dependent (SD) and spin-independent (SI) correlation functions, we have investigated the properties of liquid 3He in the presence of magnetic field at finite temperature. Our calculations have been done using the variational method based on cluster expansion of the energy functional. Our results show that the low field magnetic susceptibility obeys Curie law at high temperatures. This behavior is in a good agreement with the experimental data as well as the molecular field theory results in which the spin dependency has been introduced in correlation function. Reduced susceptibility as a function of temperature as well as reduced temperature has been also investigated, and again we have seen that the spin-dependent correlation function leads to a good agreement with the experimental data. The Landau parameter, F0a, has been calculated, and for this parameter, a value about ‑ 0.75 has been found in the case of spin-spin correlation. In the case of spin-independent correlation function, this value is about ‑ 0.7. Therefore, inclusion of spin dependency in the correlation function leads to a more compatible value of F0a with experimental data. The magnetization and susceptibility of liquid 3He have also been investigated as a function of magnetic field. Our results show a downward curvature in magnetization of system with spin-dependent correlation for all densities and relevant temperatures. A metamagnetic behavior has been observed as a maximum in susceptibility versus magnetic field, when the spin-spin correlation has been considered. This maximum occurs at 45T ≤ B ≤ 100T for all densities and temperatures. This behavior has not been observed in the case of spin-independent correlation function.

  3. Semi-catalyzed deuterium reactors for co-generation of 3He and synfuels (the CoSCD concept)

    International Nuclear Information System (INIS)

    The potential of developing semi-catalyzed deuterium reactors for co-generation of 3He and synthetic fuels is discussed. Such factors as environmental impact, siting, energy basics, and engineering technology are also discussed

  4. Search and discovery: Nobel prize in physics to Lee, Osheroff and Richardson for discovery of superfluidity in {sup 3}He

    Energy Technology Data Exchange (ETDEWEB)

    Lubkin, G.B. [American Institute of Physics, 500 Sunnyside Boulevard, Woodbury, New York 11797 (United States)

    1996-12-01

    A quarter of a century ago three Cornell experimenters found that when they cooled {sup 3}He below 3 mK it had three different superfluid phases and behaved anisotropically. {copyright} {ital 1996 American Institute of Physics.}

  5. Novel and efficient 10B lined tubelet detector as a replacement for 3He neutron proportional counters

    Science.gov (United States)

    Tsorbatzoglou, Kyriakos; McKeag, Robert D.

    2011-10-01

    This paper presents a novel and robust proportional detector which addresses the well publicized shortage of 3He gas by using a 10B lining applied to a tubelet configuration. The advantage of the tubelet structure is that it yields a detector maintaining the form factor of a conventional 3He tube whilst achieving a sensitivity of up to 75% of a 3 atm 3He device. The design and fabrication of the tubelet detector is presented and discussed with test data comparing the new detector to existing 3He and BF 3 tubes. The application of the tubelet design to security and industrial applications including retro-fitting to existing portals and suitability for high integrity oil and gas installations is addressed.

  6. Search and discovery: Nobel prize in physics to Lee, Osheroff and Richardson for discovery of superfluidity in 3He

    International Nuclear Information System (INIS)

    A quarter of a century ago three Cornell experimenters found that when they cooled 3He below 3 mK it had three different superfluid phases and behaved anisotropically. copyright 1996 American Institute of Physics

  7. Comparison of Thermal Neutron Detection Efficiency of $^{6}$Li Scintillation Glass and $^{3}$He Gas Proportional Tube

    OpenAIRE

    Xu, Ming; Tang, Zhi-Cheng; Chen, Guo-Ming; Tao, Jun-Quan

    2013-01-01

    We report on a comparison study of the $^{3}$He gas proportional tube and the $^{6}$Li incorporated scintillation glasses on thermal neutron detection efficiency. Both $^{3}$He and $^{6}$Li are used commonly for thermal neutron detection because of their high neutron capture absorption coefficient. By using a neutron source $^{252}$Cf and a paraffin moderator in an alignment system, we can get a small beam of thermal neutrons. A flash ADC is used to measure the thermal neutron spectrum of eac...

  8. Assessing the use of 3H-3He dating to determine the subsurface transit time of cave drip waters.

    Science.gov (United States)

    Kluge, Tobias; Wieser, Martin; Aeschbach-Hertig, Werner

    2010-09-01

    (3)H-(3)He measurements constitute a well-established method for the determination of the residence time of young groundwater. However, this method has rarely been applied to karstified aquifers and in particular to drip water in caves, despite the importance of the information which may be obtained. Besides the determination of transfer times of climate signals from the atmosphere through the epikarst to speleothems as climate archives, (3)H-(3)He together with Ne, Ar, Kr, Xe data may also help to give new insights into the local hydrogeology, e.g. the possible existence of a perched aquifer above a cave. In order to check the applicability of (3)H-(3)He dating to cave drips, we collected drip water samples from three adjacent caves in northwestern Germany during several campaigns. The noble gas data were evaluated by inverse modelling to obtain recharge temperature and excess air, supporting the calculation of the tritiogenic (3)He and hence the (3)H-(3)He age. Although atmospheric noble gases were often found to be close to equilibrium with the cave atmosphere, several drip water samples yielded an elevated (3)He/(4)He ratio, providing evidence for the accumulation of (3)He from the decay of (3)H. No significant contribution of radiogenic (4)He was found, corresponding to the low residence times mostly in the range of one to three years. Despite complications during sampling, conditions of a perched aquifer could be confirmed by replicate samples at one drip site. Here, the excess air indicator ΔNe was about 10 %, comparable to typical values found in aquifers in mid-latitudes. The mean (3)H-(3)He age of 2.1 years at this site presumably refers to the residence time in the perched aquifer and is lower than the entire transit time of 3.4 years estimated from the tritium data.

  9. {gamma} decay of spin-isospin states in {sup 13}N via ({sup 3}He, t{gamma}) reaction

    Energy Technology Data Exchange (ETDEWEB)

    Ihara, F.; Akimune, H.; Daito, I.; Fujimura, H.; Fujiwara, M.; Inomata, T.; Ishibashi, K.; Yoshida, H. [Osaka Univ., Ibaraki (Japan). Research Center for Nuclear Physics; Fujita, Y.

    1998-03-01

    Spin-isospin states in {sup 13}N have been studied by means of the {sup 13}C ({sup 3}He,t) reaction at and near zero degree, at E({sup 3}He)=450 MeV. Decayed {gamma}-rays from each state were measured at backward angle in coincidence with the ejectile tritons. The branching ratio of {gamma} decay for some of spin-isospin states were determined and were compared to those from previous data. (author)

  10. Analysis and depth profiling of deuterium with the D(3He,p) 4He reaction by detecting the protons at backward angles

    International Nuclear Information System (INIS)

    Detection at backward angles of protons from D(3He, p)4He presents distinct advantages with respect to the associated α particle detection used until now for depth profiling deuterium. This geometry does not require glancing incidence for good depth resolution so that rough samples may be analyzed, while the flux and energy of the elastically scattered beam particles is reduced, their pile-up problems minimized, their filtering, when necessary, with mylar absorbers or electrostatic deflectors more favourable, etc. The various contributions to the depth resolution have been calculated taking into account detector acceptance angle, size of the probing beam, energy straggling, multiple scattering and lateral spread contributions and the way to combine them discussed in detail. The 13 MeV protons emitted at 1650 for E(3He) = 700 keV were detected using a 1500 μ deep silicon surface barrier detector with a measured overall resolution of 17 keV (fwhm). The probing beam was produced with a 350 kV HVEE accelerator using 3He(2+) ions thus demonstrating the feasibility of such measurements with low energy ion implantation machines. Depth resolutions were measured and found to be in good agreement with theory. Typically, surface resolutions of 500 A were reached for incident beams normal to the target surface. This resolution could be reduced below 200 A by tilting the target with respect to the beam. The method has been applied to deuterium depth profiling in amorphous silicon hydrogenated by implantation or plasma diffusion of deuterium. A comparison with SIMS measurements is reported. (orig.)

  11. Two and three-dimensional segmentation of hyperpolarized 3He magnetic resonance imaging of pulmonary gas distribution

    Science.gov (United States)

    Heydarian, Mohammadreza; Kirby, Miranda; Wheatley, Andrew; Fenster, Aaron; Parraga, Grace

    2012-03-01

    A semi-automated method for generating hyperpolarized helium-3 (3He) measurements of individual slice (2D) or whole lung (3D) gas distribution was developed. 3He MRI functional images were segmented using two-dimensional (2D) and three-dimensional (3D) hierarchical K-means clustering of the 3He MRI signal and in addition a seeded region-growing algorithm was employed for segmentation of the 1H MRI thoracic cavity volume. 3He MRI pulmonary function measurements were generated following two-dimensional landmark-based non-rigid registration of the 3He and 1H pulmonary images. We applied this method to MRI of healthy subjects and subjects with chronic obstructive lung disease (COPD). The results of hierarchical K-means 2D and 3D segmentation were compared to an expert observer's manual segmentation results using linear regression, Pearson correlations and the Dice similarity coefficient. 2D hierarchical K-means segmentation of ventilation volume (VV) and ventilation defect volume (VDV) was strongly and significantly correlated with manual measurements (VV: r=0.98, phierarchical K-means segmentation of VV and VDV was also strongly and significantly correlated with manual measurements (VV: r=0.98, psemi-automated segmentation of 3He MRI gas distribution provides a way to generate novel pulmonary function measurements.

  12. Super enrichment of Fe-group nuclei in solar flares and their association with large 3He enrichments

    International Nuclear Information System (INIS)

    ''Fe''/He ratios at approximately 2 MeV/n have been measured in 60 solar flares and periods of enhanced fluxes during the interval 1972-1976. The observed ditribution of ratios is extremely wide with values ranging from approximately 1 to more than 1000 times the solar abundance ratio. In constrast, most of the CHO/He ratios for the same flares lie within a factor 2 of the observed mean value of 2 x 10-2. While experimental limitations prevent a complete correlation study of Fe-group and 3He abundances, comparison of flares with large Fe enrichments with flares with large 3He enrichments for the period 1969-1976 shows that a 3He-rich flare is also likely to be rich in iron. We feel that the association of 3He and Fe enrichments may be explained by a two-stage process in which a preliminary enrichment of heavy nuclei precedes the preferential acceleration of ambient 3He. Nuclear interactions are ruled out as the principal source of the enriched 3He. (author)

  13. ADC 值在儿童常见小脑肿瘤鉴别诊断中的应用%The utility of apparent diffusion coefficient in differential diagnosis of common pediatric cerebellar tumors

    Institute of Scientific and Technical Information of China (English)

    卜春晓; 张勇; 程敬亮; 李颜良

    2015-01-01

    Objective To investigate the assessment value of diffusion-weighted magnetic resonance imaging (DWI)and apparent diffusion coefficient (ADC)in the differential diagnosis of common cerebellar tumors of children.Methods 45 patients with cerebel-lar tumors were retrospectively analyzed,including 23 medulloblastomas,14 astrocytomas,and 8 ependymomas .The ADCmin of parenchyma of different tumors were measured and Receiver operating characteristic (ROC)curve were delineated.The optimum ADC value for differential diagnosis of common cerebellar tumors of children was analyzed and determined.Results The mean ADC-min of medulloblastoma (0.497 ± 0.023 )× 10 -3 mm2/s was lowest,the mean ADCmin of astrocytoma (1.572 ± 0.145 )× 10 -3 mm2/s was highest,while that of ependymoma was (0.784 ± 0.037 )× 10 -3 mm2/s.The optimum ADC to distinguish ependymomas from medulloblastomas was 0.61 1 × 10 -3 mm2/s (100% sensitivity and 95.7% specificity).The optimum ADC to distinguish low-grade astrocytomas from ependymomas was 1.064×10 -3 mm2/s (92.9% sensitivity and 100% specificity).Conclu-sion ADC is very helpful with differential diagnosis of common cerebellar tumors of children.%目的:探讨扩散加权成像(DWI)和表观扩散系数(ADC)值在鉴别儿童小脑常见肿瘤中的价值。方法回顾性分析本院经手术病理证实的45例儿童小脑肿瘤患者,其中髓母细胞瘤23例,星形细胞瘤14例,室管膜瘤8例。测量不同肿瘤的实质部分的最小 ADC 值,绘制 ROC 曲线,预测儿童常见小脑肿瘤鉴别诊断的最佳 ADC 值。结果髓母细胞瘤的平均最小 ADC 值最低,为(0.497±0.023)×10-3 mm2/s;低级星形细胞瘤的平均最小 ADC 值最高,为(1.572±0.145)×10-3 mm2/s;室管膜瘤的平均最小ADC 值为(0.784±0.037)×10-3 mm2/s。髓母细胞瘤鉴别室管膜瘤的最佳 ADC 值为0.611×10-3 mm2/s,敏感度100%,特异性95.7%;室管膜瘤鉴别低级星形细胞瘤的最佳 ADC 值为1.064×10-3 mm2/s,敏感度92

  14. Application value of apparent diffusion coefficient in diagnosis of different histological subtypes of lung cancers%表观扩散系数值在鉴别不同组织学类型肺癌中的价值

    Institute of Scientific and Technical Information of China (English)

    陈利华; 陈永峰; 张久权; 王文伟; 夏云宝; 王健

    2012-01-01

    目的 探讨DWI表观扩散系数(ADC)值鉴别肺癌组织学类型的价值.方法 对58例高度怀疑肺癌患者(男39例,女19例)行胸部DWI检查,b值选择为50和1000 s/mm2,计算ADC值.采用单因素方差分析方法检测不同组织学类型肺癌ADC值的差异,并应用ROC曲线评价ADC值鉴别肺癌组织学类型的能力.结果 小细胞肺癌的平均ADC值为(1.02±0.24)×10-3 mm2/s;非小细胞肺癌的平均ADC值为(1.03±0.24)×10-3 mm2/s,其中腺癌、鳞癌的平均ADC值分别为(1.10±0.14)×10-3 mm2/s、(0.89±0.09)×10-3 mm2/s.腺癌的平均ADC值显著高于鳞癌(P<0.001).在非小细胞肺癌中,腺癌的ROC曲线下面积为0.91±0.04.结论 腺癌的平均ADC值显著高于鳞癌;ADC值有助于鉴别肺腺癌和鳞癌.%Objective To investigate the possibility of using the apparent diffusion coefficient (ADC) value to differentiate histological subtypes of lung cancers. Methods Fifty-eight patients with suspected lung cancer (39 men, 19 women) underwent magnetic resonance diffusion-weighted imaging (DWI)of the chest with b factor of 50 and 1000 s/mm2. ADC values were calculated and correlated with histological subtypes of lung cancers. ROC analysis of ADC value was used to predict histological subtypes. Results The mean ADC value of small and non-small cell lung cancer was (1. 02±0. 24) X 10-3 mm2/s and (1. 03 ± 0. 24) X 10-3 mm2/s, respectively, while of squamous cell carcinoma and adenocarcinoma was (0. 89±0. 09)X10-3 mm2/s and (1. 10±0. 14)X10-3 mm2/s, respectively. ADC value of adenocarcinoma was significantly higher than that of squamous cell carcinoma (P<0. 001). The area under ROC curve was 0. 91±0. 04 for adenocarcinoma of non-small cell lung cancer. Conclusion The mean ADC value of lung adenocarcinoma is significantly higher than that of squamous cell carcinoma. ADC value may help to differentiate the histological subtypes of lung cancers.

  15. Remembering apparent behavior

    DEFF Research Database (Denmark)

    Wagoner, Brady

    2011-01-01

    The present experiment systematically investigates the role of narrative templates (Wertsch, 2002) in remembering. To stimulate the construction of a diversity of narratives I used Heider and Simmel’s (1944) celebrated “apparent behavior” film, in which geometric shapes moving around a screen are...

  16. Particle transport in 3He-rich events: wave-particle interactions and particle anisotropy measurements

    Directory of Open Access Journals (Sweden)

    T. Hada

    Full Text Available Energetic particles and MHD waves are studied using simultaneous ISEE-3 data to investigate particle propagation and scattering between the source near the Sun and 1 AU. 3 He-rich events are of particular interest because they are typically low intensity "scatter-free" events. The largest solar proton events are of interest because they have been postulated to generate their own waves through beam instabilities. For 3 He-rich events, simultaneous interplanetary magnetic spectra are measured. The intensity of the interplanetary "fossil" turbulence through which the particles have traversed is found to be at the "quiet" to "intermediate" level of IMF activity. Pitch angle scattering rates and the corresponding particle mean free paths lW - P are calculated using the measured wave intensities, polarizations, and k directions. The values of lW - P are found to be ~ 5 times less than the value of lHe , the latter derived from He intensity and anisotropy time profiles. It is demonstrated by computer simulation that scattering rates through a 90° pitch angle are lower than that of other pitch angles, and that this is a possible explanation for the discrepancy between the lW - P and lHe values. At this time the scattering mechanism(s is unknown. We suggest a means where a direct comparison between the two l values could be made. Computer simulations indicate that although scattering through 90° is lower, it still occurs. Possibilities are either large pitch angle scattering through resonant interactions, or particle mirroring off of field compression regions. The largest solar proton events are analyzed to investigate the possibilities of local wave generation at 1 AU. In accordance with the results of a previous calculation (Gary et al., 1985 of beam stability, proton beams at 1 AU are found to be marginally stable. No evidence for substantial wave amplitude was found. Locally generated waves, if present, were less than 10-3 nT 2 Hz-1 at the leading

  17. Search for eta-mesic 4He in the dd->3He n pi0 and dd->3He p pi- reactions with the WASA-at-COSY facility

    CERN Document Server

    Adlarson, P; Bardan, W; Bashkanov, M; Bergmann, F S; Berlowski, M; Bhatt, H; Bondar, A; Buescher, 9 M; Calen, H; Ciepal, I; Clement, H; Czerwinski, E; Demmich, K; Engels, R; Erven, A; Erven, W; Eyrich, W; Fedorets, P; Foehl, K; Fransson, K; Goldenbaum, F; Goswami, A; Grigoryev, K; Gullstroem, C -O; Heijkenskjoeld, L; Hejny, V; Huesken, N; Jarczyk, L; Johansson, T; Kamys, B; Kelkar, N G; Kemmerling, G; Khatri, G; Khoukaz, A; Khreptak, O; Kirillov, D A; Kistryn, S; Kleines, H; Klos, B; Krzemien, W; Kulessa, P; Kupsc, A; Kuzmin, A; Lalwani, K; Lersch, D; Lorentz, B; Magiera, A; Maier, R; Marciniewski, P; Marianski, B; Morsch, H -P; Moskal, P; Ohm, H; del Rio, E Perez; Piskunov, N M; Prasuhn, D; Pszczel, D; Pysz, K; Pyszniak, A; Ritman, J; Roy, A; Rudy, Z; Rundel, O; Sawant, S; Schadmand, S; Schaetti-Ozerianska, I; Sefzick, T; Serdyuk, V; Shwartz, B; Sitterberg, K; Skorodko, T; Skurzok, M; Smyrski, J; Sopov, V; Stassen, R; Stepaniak, J; Stephan, E; Sterzenbach, G; Stockhorst, H; Stroeher, H; Szczurek, A; Trzcinski, A; Varma, R; Wolke, M; Wronska, A; Wuestner, P; Yamamoto, A; Zabierowski, J; Zielinski, M J; Zlomanczuk, J; Zupranski, P; Zurek, M

    2016-01-01

    The search for 4He-eta bound states was performed with the WASA-at-COSY facility via the measurement of the excitation function for the dd->3He n pi0 and dd->3He p pi- processes. The beam momentum was varied continuously between 2.127 GeV/c and 2.422 GeV/c, corresponding to the excess energy for the dd->4He eta reaction ranging from Q=-70 MeV to Q=30 MeV. The luminosity was determined based on the dd->3He n reaction and quasi-free proton-proton scattering via dd->pp n_spectator n_spectator reactions. The excitation functions determined independently for the measured reactions do not reveal a structure which could be interpreted as a narrow mesic nucleus. Therefore, the upper limits of the total cross sections for the bound state production and decay in dd->(4He-eta)_bound->3He n pi0 and dd->(4He-eta)_bound->3He p pi- processes were determined taking into account the isospin relation between both the channels considered. The results of the analysis depend on the assumptions of the N* momentum distribution in t...

  18. Non-intrusive measurement of tritium activity in waste drums by modelling a 3He leak quantified by mass spectrometry

    International Nuclear Information System (INIS)

    This study deals with a new method that makes it possible to measure very low tritium quantities inside radioactive waste drums. This indirect method is based on measuring the decaying product, 3He, and requires a study of its behaviour inside the drum. Our model considers 3He as totally free and its leak through the polymeric joint of the drum as two distinct phenomena: permeation and laminar flow. The numerical simulations show that a pseudo-stationary state takes place. Thus, the 3He leak corresponds to the tritium activity inside the drum but it appears, however, that the leak peaks when the atmospheric pressure variations induce an overpressure in the drum. Nevertheless, the confinement of a drum in a tight chamber makes it possible to quantify the 3He leak. This is a non-intrusive measurement of its activity, which was experimentally checked by using reduced models, representing the drum and its confinement chamber. The drum's confinement was optimised to obtain a reproducible 3He leak measurement. The gaseous samples taken from the chamber were purified using selective adsorption onto activated charcoals at 77 K to remove the tritium and pre-concentrate the 3He. The samples were measured using a leak detector mass spectrometer. The adaptation of the signal acquisition and the optimisation of the analysis parameters made it possible to reach the stability of the external calibrations using standard gases with a 3He detection limit of 0.05 ppb. Repeated confinement of the reference drums demonstrated the accuracy of this method. The uncertainty of this non-intrusive measurement of the tritium activity in 200-liter drums is 15% and the detection limit is about 1 GBq after a 24 h confinement. These results led to the definition of an automated tool able to systematically measure the tritium activity of all storage waste drums. (authors)

  19. X-rays from antiprotonic sup 3 He and sup 4 He

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, M.; Bacher, R.; Bluem, P.; Gotta, D.; Heitlinger, K.; Kunold, W.; Rohmann, D. (Kernforschungszentrum Karlsruhe GmbH (Germany, F.R.). Inst. fuer Kernphysik Karlsruhe Univ. (T.H.) (Germany, F.R.). Inst. fuer Experimentelle Kernphysik); Egger, J.; Simons, L.M. (Paul Scherrer Inst. (PSI), Villigen (Switzerland)); Elsener, K. (European Organization for Nuclear Research, Geneva (Switzerland))

    1991-02-01

    Antiprotonic X-rays from the helium isotopes have been observed at pressures of 36, 72, 375 and 600 mbar. The antiproton beam from LEAR with momenta of 309 and 202 MeV/c has been stopped at these pressures using the cyclotron trap. The X-rays were detected with Si(Li) and intrinsic Ge semiconductor detectors. Absolute X-ray yields were determined and the strong-interaction 2p shifts and the 2p and 3d broadenings measured to be {epsilon}{sub 2p}=(-17{plus minus}4) eV, {Gamma}{sub 2p}=(25{plus minus}9) eV and {Gamma}{sub 3d}=(2.14{plus minus}0.18) meV for anti p{sup 3}He and {epsilon}{sub 2p}=(-18{plus minus}2) eV, {Gamma}{sub 2p}=(45{plus minus}5) eV and {Gamma}{sub 3d}=(2.36{plus minus}0.10) meV for anti p{sup 4}He. (orig.).

  20. Parametric excitation of the J=2+ modes by zero sound in superfluid 3He-B

    International Nuclear Information System (INIS)

    We discuss order-parameter collective modes in weakly inhomogeneous states of superfluid 3He-B, i.e., states in which the scale of the inhomogeneities is considerably longer than the coherence length ξ0=vt/2πTc and the energy associated with the inhomogeneity is small compared to the condensation energy. The theory describes resonance phenomena between order-parameter modes and zero sound. We discuss two specific cases, both of which involve excitation of the J=2+ modes via a parametric field that lifts the selection rule due to particle-hole symmetry. In the case of a static superflow the modes with J=2+, M=±1 couple to sound for qparallelH, and should be observable as Zeeman states with a maximum absorption that scales as the square of the superflow velocity. The J=2+ modes may also be excited parametrically in a three-wave resonance process involving two zero-sound phonons. We summarize the nonlinear response theory for two-phonon excitation of these modes. (orig.)

  1. Search for Solar Axions Produced in the $p + d \\rightarrow\\rm{^3He}+ A$ Reaction

    CERN Document Server

    Derbin, A V; Muratova, V N; 10.3103/S106287381006016X

    2010-01-01

    A search for the axioelectric absorption of 5.5-MeV solar axions produced in the $p+d\\rightarrow \\rm{^3He}+\\gamma(5.5 \\rm{MeV})$ reaction was performed with two BGO detectors placed inside a low-background setup. A model independent limit on axion-photon and axion-nucleon couplings was obtained: $|g_{Ae}\\times g_{AN}| \\leq 3.2\\times 10^{-9} (m_A=0)$. Constraints on the axion-electron coupling constant were obtained for axions with masses in the $(0.1-1.0)$ MeV range: $g_{Ae}\\leq (1.8-9.0)\\times 10^{-7}$. The solar positron flux from $A\\rightarrow e^-+e^+$ decay was determined for axions with masses $m_A > 2m_e$. Using the existing experimental data on the interplanetary positron flux, a new constraint on the axion-electron coupling constant for axions with masses in the $(1.2-5.4)$ MeV range was obtained: $g_{Ae} \\leq (1-5)\\times 10^{-17}$.

  2. End-compensated magnetostatic cavity for polarized 3He neutron spin filters.

    Science.gov (United States)

    McIver, J W; Erwin, R; Chen, W C; Gentile, T R

    2009-06-01

    We have expanded upon the "Magic Box" concept, a coil driven magnetic parallel plate capacitor constructed out of mu-metal, by introducing compensation sections at the ends of the box that are tuned to limit end-effects similar to those of short solenoids. This ability has reduced the length of the magic box design without sacrificing any loss in field homogeneity, making the device far more applicable to the often space limited neutron beam line. The appeal of the design beyond affording longer polarized 3He lifetimes is that it provides a vertical guide field, which facilitates neutron spin transport for typical polarized beam experiments. We have constructed two end-compensated magic boxes of dimensions 28.4 x 40 x 15 cm3 (length x width x height) with measured, normalized volume-averaged transverse field gradients ranging from 3.3 x 10(-4) to 6.3 x 10(-4) cm(-1) for cell sizes ranging from 8.1 x 6.0 to 12.0 x 7.9 cm2 (diameter x length), respectively.

  3. End-compensated magnetostatic cavity for polarized {sup 3}He neutron spin filters

    Energy Technology Data Exchange (ETDEWEB)

    McIver, J. W.; Erwin, R.; Gentile, T. R. [National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, Maryland 20899 (United States); Chen, W. C. [National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, Maryland 20899 (United States); Indiana University, Bloomington, Indiana 47408 (United States)

    2009-06-15

    We have expanded upon the ''Magic Box'' concept, a coil driven magnetic parallel plate capacitor constructed out of mu-metal, by introducing compensation sections at the ends of the box that are tuned to limit end-effects similar to those of short solenoids. This ability has reduced the length of the magic box design without sacrificing any loss in field homogeneity, making the device far more applicable to the often space limited neutron beam line. The appeal of the design beyond affording longer polarized {sup 3}He lifetimes is that it provides a vertical guide field, which facilitates neutron spin transport for typical polarized beam experiments. We have constructed two end-compensated magic boxes of dimensions 28.4x40x15 cm{sup 3} (lengthxwidthxheight) with measured, normalized volume-averaged transverse field gradients ranging from 3.3x10{sup -4} to 6.3x10{sup -4} cm{sup -1} for cell sizes ranging from 8.1x6.0 to 12.0x7.9 cm{sup 2} (diameterxlength), respectively.

  4. An array of low-background 3He proportional counters for theSudbury Neutrino Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Amsbaugh, J.F.; Anaya, J.M.; Banar, J.; Bowles, T.J.; Browne,M.C.; Bullard, T.V.; Burritt, T.H.; Cox-Mobrand, G.A.; Dai, X.; H.Deng,X.; Di Marco, M.; Doe, P.J.; Dragowsky, M.R.; Duba, C.A.; Duncan, F.A.; Earle, E.D.; Elliott, S.R.; Esch, E.-I.; Fergani, H.; Formaggio, J.A.; Fowler, M.M.; Franklin, J.E.; Geissbuehler, P.; Germani, J.V.; Goldschmidt, A.; Guillian, E.; Hallin, A.L.; Harper, G.; Harvey, P.J.; Hazama, R.; Heeger, K.M.; Heise, J.; Hime, A.; Howe, M.A.; Huang, M.; Kormos, L.L.; Kraus, C.; Krauss, C.B.; Law, J.; Lawson, I.T.; Lesko,K.T.; Loach, J.C.; Majerus, S.; Manor, J.; McGee, S.; Miknaitis, K.K.S.; Miller, G.G.; Morissette, B.; Myers, A.; Oblath, N.S.; O' Kee, H.M.; Ollerhead, R.W.; Peeters, S.J.M.; Poon, A.W.P.; Prior, G.; Reitzner,S.D.; Rielage, K.; Robertson, R.G.H.; Skensved, P.; Smith, A.R.; Smith,M.W.E.; Steiger, T.D.; Stonehill,L.C.; Thornewell, P.M.; Tolich, N.; VanDevender, B.A.; VanWechel, T.D.; Wall, B.L.; Tseung, H.W.C.; Wendland,J.; West, N.; Wilhelmy, J.B.; Wilkerson, J.F.; Wouters, J.M.

    2007-02-01

    An array of Neutral-Current Detectors (NCDs) has been builtin order to make a unique measurement of the total active ux of solarneutrinos in the Sudbury Neutrino Observatory (SNO). Data in the thirdphase of the SNO experiment were collected between November 2004 andNovember 2006, after the NCD array was added to improve theneutral-current sensitivity of the SNO detector. This array consisted of36 strings of proportional counters lled with a mixture of 3He and CF4gas capable of detecting the neutrons liberated by the neutrino-deuteronneutral current reaction in the D2O, and four strings lled with a mixtureof 4He and CF4 gas for background measurements. The proportional counterdiameter is 5 cm. The total deployed array length was 398 m. The SNO NCDarray is the lowest-radioactivity large array of proportional countersever produced. This article describes the design, construction,deployment, and characterization of the NCD array, discusses theelectronics and data acquisition system, and considers event signaturesand backgrounds.

  5. An array of low-background $^3$He proportional counters for the Sudbury Neutrino Observatory

    CERN Document Server

    Amsbaugh, J F; Banar, J C; Bowles, T J; Browne, M C; Bullard, T V; Burritt, T H; Cox-Mobrand, G A; Dai, X; Deng, H; Di Marco, M; Doe, P J; Dragowsky, M R; Duba, C A; Duncan, F A; Earle, E D; Elliott, S R; Esch, E -I; Fergani, H; Formaggio, J A; Fowler, M M; Franklin, J E; Geissbühler, P; Germani, J V; Goldschmidt, A; Guillian, E; Hallin, A L; Harper, G; Harvey, P J; Hazama, R; Heeger, K M; Heise, J; Hime, A; Howe, M A; Huang, M; Kormos, L L; Kraus, C V; Krauss, C B; Law, J; Lawson, I T; Lesko, K T; Loach, J C; Majerus, S; Manor, J; McGee, S; Miknaitis, K K S; Miller, G G; Morissette, B; Myers, A; Oblath, N S; O'Keeffe, H M; Ollerhead, R W; Peeters, S J M; Poon, A W P; Prior, G; Reitzner, S D; Rielage, K; Robertson, R G H; Skensved, P; Smith, A R; Smith, M W E; Steiger, T D; Stonehill, L C; Thornewell, P M; Tolich, N; VanDevender, B A; Van Wechel, T D; Wall, B L; Tseung, H Wan Chan; Wendland, J; West, N; Wilhelmy, J B; Wilkerson, J F; Wouters, J M

    2007-01-01

    An array of Neutral-Current Detectors (NCDs) has been built in order to make a unique measurement of the total active flux of solar neutrinos in the Sudbury Neutrino Observatory (SNO). Data in the third phase of the SNO experiment were collected between November 2004 and November 2006, after the NCD array was added to improve the neutral-current sensitivity of the SNO detector. This array consisted of 36 strings of proportional counters filled with a mixture of $^3$He and CF$_4$ gas capable of detecting the neutrons liberated by the neutrino-deuteron neutral current reaction in the D$_2$O, and four strings filled with a mixture of $^4$He and CF$_4$ gas for background measurements. The proportional counter diameter is 5 cm. The total deployed array length was 398 m. The SNO NCD array is the lowest-radioactivity large array of proportional counters ever produced. This article describes the design, construction, deployment, and characterization of the NCD array, discusses the electronics and data acquisition sys...

  6. An array of low-background 3He proportional counters for the Sudbury Neutrino Observatory

    Science.gov (United States)

    Amsbaugh, J. F.; Anaya, J. M.; Banar, J.; Bowles, T. J.; Browne, M. C.; Bullard, T. V.; Burritt, T. H.; Cox-Mobrand, G. A.; Dai, X.; Deng, H.; Di Marco, M.; Doe, P. J.; Dragowsky, M. R.; Duba, C. A.; Duncan, F. A.; Earle, E. D.; Elliott, S. R.; Esch, E.-I.; Fergani, H.; Formaggio, J. A.; Fowler, M. M.; Franklin, J. E.; Geissbühler, P.; Germani, J. V.; Goldschmidt, A.; Guillian, E.; Hallin, A. L.; Harper, G.; Harvey, P. J.; Hazama, R.; Heeger, K. M.; Heise, J.; Hime, A.; Howe, M. A.; Huang, M.; Kormos, L. L.; Kraus, C.; Krauss, C. B.; Law, J.; Lawson, I. T.; Lesko, K. T.; Loach, J. C.; Majerus, S.; Manor, J.; McGee, S.; Miknaitis, K. K. S.; Miller, G. G.; Morissette, B.; Myers, A.; Oblath, N. S.; O'Keeffe, H. M.; Ollerhead, R. W.; Peeters, S. J. M.; Poon, A. W. P.; Prior, G.; Reitzner, S. D.; Rielage, K.; Robertson, R. G. H.; Skensved, P.; Smith, A. R.; Smith, M. W. E.; Steiger, T. D.; Stonehill, L. C.; Thornewell, P. M.; Tolich, N.; VanDevender, B. A.; Van Wechel, T. D.; Wall, B. L.; Wan Chan Tseung, H.; Wendland, J.; West, N.; Wilhelmy, J. B.; Wilkerson, J. F.; Wouters, J. M.

    2007-09-01

    An array of Neutral-Current Detectors (NCDs) has been built in order to make a unique measurement of the total active flux of solar neutrinos in the Sudbury Neutrino Observatory (SNO). Data in the third phase of the SNO experiment were collected between November 2004 and 2006, after the NCD array was added to improve the neutral-current sensitivity of the SNO detector. This array consisted of 36 strings of proportional counters filled with a mixture of 3He and CF 4 gas capable of detecting the neutrons liberated by the neutrino-deuteron neutral-current reaction in the D 2O, and four strings filled with a mixture of 4He and CF 4 gas for background measurements. The proportional counter diameter is 5 cm. The total deployed array length was 398 m. The SNO NCD array is the lowest-radioactivity large array of proportional counters ever produced. This article describes the design, construction, deployment, and characterization of the NCD array, discusses the electronics and data acquisition system, and considers event signatures and backgrounds.

  7. Narrow structure in η-photoproducion off {sup 2}H and {sup 3}He

    Energy Technology Data Exchange (ETDEWEB)

    Witthauer, Lilian; Werthmueller, Dominik [Department of Physics, University of Basel (Switzerland); Collaboration: A2-Collaboration

    2013-07-01

    Large efforts have been made in the last years to investigate the complicated excitation spectrum of the nucleons. Especially η-Photoproduction has been studied by many collaborations. Experiments at CBELSA/TAPS and GRAAL revealed a bump-like structure in the quasi-free η-Photoproduction on the neutron, which is not seen on the proton (I. Jaegle et al., PRL 100 (2008), V.Kuznetsov et al., PLB 647 (2007)). To examine this structure high statistics experiments using the A2 detector setup with the Crystal Ball calorimeter and the TAPS detector at the electron acceleration facility MAMI have been carried out. To exclude any possibility that the structure could arise from nuclear effects, η-photoproduction in coincidence with recoil nucleons has been measured on two different targets, namely {sup 2}H and {sup 3}He. This talk gives an overview over the final results on quasi-free inclusive and exclusive η-Photoproduction off quasi-free protons and neutrons.

  8. Dispersion induced splitting of the collective mode spectrum in A-phase of superfluid 3He

    International Nuclear Information System (INIS)

    The whole collective mode spectrum in A-phase of superfluid 3He with dispersion corrections is calculated. The degeneracy of clapping-modes depends on the direction of the collective mode momentum k with respect to the vector l (mutual orbital moment of Cooper pairs), namely: the mode degeneracy remains the same as in case of zero momentum k for k-parallel l only. For any other directions there is a three-fold splitting of these modes, which reaches maximum for k-perpendicular l. The obtained results means that new interesting features can be observed in ultrasound experiments in axial-phase: the change of the number of peaks in ultrasound absorption into clapping-mode. Single peak, observed for these modes in axial-phase by Ling et al. [R. Ling, W. Wojtanowski, J. Saunders, E.R. Dobbs, J. Low Temp. Phys. 78 (1990) 187] will split into three peaks under change the ultrasound direction with respect to the vector l.

  9. NMR Properties of the Polar Phase of Superfluid ^3He in Anisotropic Aerogel Under Rotation

    Science.gov (United States)

    Mineev, V. P.

    2016-09-01

    The polar phase of superfluid ^3He is stable in "nematically ordered" densed aerogel. A rotating vessel with the polar superfluid can be filled either by an array of the single quantum vortices or by an array of the half-quantum vortices. It is shown that the inhomogeneous distribution of the spin part of the order parameter arising in an array of half-quantum vortices in strong enough magnetic field tilted to the average direction of aerogel strands leads to the appearance of a satellite in the NMR signal shifted in the negative direction with respect to the Larmor frequency. The satellite is absent in the case of an array of single quantum vortices which allows to distinguish these two configurations. The polar state in the anisotropic aerogel with lower density transforms at lower temperatures to the axipolar state. The array of half-quantum vortices created in the polar phase keeps its structure under transition to the axipolar state. The temperature dependence of the vortex-satellite NMR frequency is found to be slower below the transition temperature to the axipolar state.

  10. The 3He long-counter TETRA at the ALTO ISOL facility

    Science.gov (United States)

    Testov, D.; Verney, D.; Roussière, B.; Bettane, J.; Didierjean, F.; Flanagan, K.; Franchoo, S.; Ibrahim, F.; Kuznetsova, E.; Li, R.; Marsh, B.; Matea, I.; Penionzhkevich, Yu.; Pai, H.; Smirnov, V.; Sokol, E.; Stefan, I.; Suzuki, D.; Wilson, J. N.

    2016-04-01

    A new β-decay station (BEDO) has been installed behind the PARRNe mass separator operated on-line at the electron-driven ALTO ISOL facility. The station is equipped with a movable tape collector allowing the creation of the radioactive sources of interest at the very center of a modular detection system. The mechanical structure was designed to host various assemblies of detectors in compact geometry. We report here the first on-line use of this system equipped with the 4π 3He neutron counter TETRA built at JINR Dubna associated with HPGe and plastic 4π β detectors. The single neutron detection efficiency achieved is 53(2)% measured using the 252Cf source. For β-delayed neutron measurements the neutron detection efficiency was derived from the comparison of gated γ-spectra. The on-line commissioning of the TETRA setup was performed with laser-ionized gallium beams. β and neutron events were recorded as a function of time. From these data we report P1n(82Ga)=22(2)% and T1/2(82Ga)=0.604(11) s in good agreement with values available in the literature. The new detection system will be used in other experiments aimed at investigations of β-decay properties of neutron-rich isotopes produced at ALTO.

  11. CAST search for sub-eV mass solar axions with $^{3}$He buffer gas

    CERN Document Server

    Aune, S; Belov, A; Borghi, S; Brauninger, H; Cantatore, G; Carmona, J M; Cetin, S A; Collar, J I; Dafni, T; Davenport, M; Eleftheriadis, C; Elias, N; Ezer, C; Fanourakis, G; Ferrer-Ribas, E; Friedrich, P; Galan, J; Garcia, J A; Gardikiotis, A; Gazis, E N; Geralis, T; Giomataris, I; Gninenko, S; Gomez, H; Gruber, E; Guthorl, T; Hartmann, R; Haug, F; Hasinoff, M D; Hoffmann, D H H; Iguaz, F J; Irastorza, I G; Jacoby, J; Jakovcic, K; Karuza, M; Konigsmann, K; Kotthaus, R; Krcmar, M; Kuster, M; Lakic, B; Laurent, J M; Liolios, A; Ljubicic, A; Lozza, V; Lutz, G; Luzon, G; Morales, J; Niinikoski, T; Nordt, A; Papaevangelou, T; Pivovaroff, M J; Raffelt, G; Rashba, T; Riege, H; Rodriguez, A; Rosu, M; Ruz, J; Savvidis, I; Silva, P S; Solanki, S.K; Stewart, L; Tomas, A; Tsagri, M; van Bibber, K; Vafeiadis, T; Villar, J A; Vogel, J K; Yildiz, S C; Zioutas, K

    2011-01-01

    The CERN Axion Solar Telescope (CAST) has extended its search for solar axions by using 3He as a buffer gas. At T=1.8 K this allows for larger pressure settings and hence sensitivity to higher axion masses than our previous measurements with 4He. With about 1 h of data taking at each of 252 different pressure settings we have scanned the axion mass range 0.39 eV < m_a < 0.64 eV. From the absence of excess X-rays when the magnet was pointing to the Sun we set a typical upper limit on the axion-photon coupling of g_ag < 2.3 x 10^{-10} GeV^{-1} at 95% CL, the exact value depending on the pressure setting. KSVZ axions are excluded at the upper end of our mass range, the first time ever for any solar axion search. In future we will extend our search to m_a < 1.15 eV, comfortably overlapping with cosmological hot dark matter bounds.

  12. Source size and time dependence of multifragmentation induced by GeV {sup 3}He beams

    Energy Technology Data Exchange (ETDEWEB)

    Wang, G.; Kwiatkowski, K.; Bracken, D.S.; Renshaw Foxford, E.; Hsi, W.; Morley, K.B.; Viola, V.E.; Yoder, N.R. [Departments of Chemistry and Physics and IUCF, Indiana University, Bloomington, Indiana 47405 (United States); Volant, C.; Legrain, R.; Pollacco, E.C. [DAPNIA/SPhN, CEA/Saclay, F-91191 Gif-sur-Yvette (France); Korteling, R.G. [Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, (Canada) V5A 156; Friedman, W.A. [Department of Physics, University of Wisconsin, Madison, Wisconsin 53706 (United States); Botvina, A. [INFN and Department of Physics, University of Bologna, 40126 Bologna (Italy); Brzychczyk, J. [Institute of Physics, Jagiellonian University, Krakow (Poland); Breuer, H. [Department of Physics, University of Maryland, College Park, Maryland 20740 (United States)

    1999-07-01

    To investigate the source size and time dependence of multifragmentation reactions, small- and large-angle relative velocity correlations between coincident complex fragments have been measured for the 1.8{endash}4.8 GeV {sup 3}He+{sup nat}Ag, {sup 197}Au systems. The results support an evolutionary scenario for the fragment emission process in which lighter IMFs (Z{approx_lt}6) are emitted from a hot, more dense source prior to breakup of an expanded residue. For the most highly excited residues, for which there is a significant yield of fragments with very soft energy spectra (E/A{le}3 MeV), comparisons with an {ital N}-body simulation suggest a breakup time of {tau}{approximately}50 fm/c for the expanded residue. Comparison of these data with both the evolutionary expanding emitting source model and the Copenhagen statistical multifragmentation model shows good agreement for heavier IMF{close_quote}s formed in the final breakup stage, but only the evolutionary model is successful in accounting for the lighter IMFs. thinsp {copyright} {ital 1999} {ital The American Physical Society}

  13. Source size and time dependence of multifragmentation induced by GeV 3He beams

    International Nuclear Information System (INIS)

    To investigate the source size and time dependence of multifragmentation reactions, small- and large-angle relative velocity correlations between coincident complex fragments have been measured for the 1.8 - 4.8 GeV 3He+natAg, 197Au systems. The results support an evolutionary scenario for the fragment emission process in which lighter IMFs (Z approx-lt 6) are emitted from a hot, more dense source prior to breakup of an expanded residue. For the most highly excited residues, for which there is a significant yield of fragments with very soft energy spectra (E/A≤3 MeV), comparisons with an N-body simulation suggest a breakup time of τ∼50 fm/c for the expanded residue. Comparison of these data with both the evolutionary expanding emitting source model and the Copenhagen statistical multifragmentation model shows good agreement for heavier IMF close-quote s formed in the final breakup stage, but only the evolutionary model is successful in accounting for the lighter IMFs. copyright 1999 The American Physical Society

  14. Source size and time dependence of multifragmentation induced by GeV [sup 3]He beams

    Energy Technology Data Exchange (ETDEWEB)

    Wang, G.; Kwiatkowski, K.; Bracken, D.S.; Renshaw Foxford, E.; Hsi, W.; Morley, K.B.; Viola, V.E.; Yoder, N.R. (Departments of Chemistry and Physics and IUCF, Indiana University, Bloomington, Indiana 47405 (United States)); Volant, C.; Legrain, R.; Pollacco, E.C. (DAPNIA/SPhN, CEA/Saclay, F-91191 Gif-sur-Yvette (France)); Korteling, R.G. (Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, (Canada) V5A 156); Friedman, W.A. (Department of Physics, University of Wisconsin, Madison, Wisconsin 53706 (United States)); Botvina, A. (INFN and Department of Physics, University of Bologna, 40126 Bologna (Italy)); Brzychczyk, J. (Institute of Physics, Jagiellonian University, Krakow (Poland)); Breuer, H. (Department of Physics, University of Maryland, College Park, Maryland 20740 (United States))

    1999-07-01

    To investigate the source size and time dependence of multifragmentation reactions, small- and large-angle relative velocity correlations between coincident complex fragments have been measured for the 1.8[endash]4.8 GeV [sup 3]He+[sup nat]Ag, [sup 197]Au systems. The results support an evolutionary scenario for the fragment emission process in which lighter IMFs (Z[approx lt]6) are emitted from a hot, more dense source prior to breakup of an expanded residue. For the most highly excited residues, for which there is a significant yield of fragments with very soft energy spectra (E/A[le]3 MeV), comparisons with an [ital N]-body simulation suggest a breakup time of [tau][approximately]50 fm/c for the expanded residue. Comparison of these data with both the evolutionary expanding emitting source model and the Copenhagen statistical multifragmentation model shows good agreement for heavier IMF[close quote]s formed in the final breakup stage, but only the evolutionary model is successful in accounting for the lighter IMFs. thinsp [copyright] [ital 1999] [ital The American Physical Society

  15. The injection of ten electron/$^{3}$He-rich SEP events

    CERN Document Server

    Wang, Linghua; Mason, Glenn M; Lin, Robert P; Li, Gang

    2016-01-01

    We have derived the particle injections at the Sun for ten good electron/$^{3}$He-rich solar energetic particle (SEP) events, using a 1.2 AU particle path length (suggested by analysis of the velocity dispersion). The inferred solar injections of high-energy ($\\sim$10 to 300 keV) electrons and of $\\sim$MeV/nucleon ions (carbon and heavier) start with a delay of 17$\\pm$3 minutes and 75$\\pm$14 minutes, respectively, after the injection of low-energy ($\\sim$0.4 to 9 keV) electrons. The injection duration (averaged over energy) ranges from $\\sim$200 to 550 minutes for ions, from $\\sim$90 to 160 minutes for low-energy electrons, and from $\\sim$10 to 30 minutes for high-energy electrons. Most of the selected events have no reported H$\\alpha$ flares or GOES SXR bursts, but all have type III radio bursts that typically start after the onset of a low-energy electron injection. All nine events with SOHO/LASCO coverage have a relatively fast ($>$570km/s), mostly narrow ($\\lesssim$30$^{\\circ}$), west-limb coronal mass ej...

  16. Spin waves in the B-phase of superfluid 3He in confined cylindrical geometry

    International Nuclear Information System (INIS)

    We describe experiments on superfluid 3He in a cylinder of 1 mm in diameter. This geometry causes the preferred orientation of the n-vector in the superfluid B-phase to be locally different, resulting in a curved configuration across the sample. Exclusive to our experiment is the observation that we succeeded in obtaining a texture which is metastable and unchanged in our pressure and temperature ranges, most likely because the experiment is performed at low pressures and low magnetic fields. As this texture can be considered as a potential for spin waves, we had the unique opportunity to study spin waves for several pressures in exactly the same texture. Our geometry causes this texture potential to be nearly quadratic, allowing an analytic solution of the theory which can be compared to our experimental results. As predicted we find the intensities of all spin wave modes more or less equal. Increasing the pressure shows a gradual increase in the number of spin wave modes in our cell. Finally we were able to cause a transition from the metastable to the predicted stable texture, concluding unexpectedly that the metastable texture is realized if the growing (or cooling) speed is sufficiently slow.

  17. A capture-gated neutron calorimeter using plastic scintillators and 3He drift tubes

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhehui [Los Alamos National Laboratory; Morris, Christopher L [Los Alamos National Laboratory; Spaulding, Randy J [Los Alamos National Laboratory; Bacon, Jeffrey D [Los Alamos National Laboratory; Borozdin, Konstantin N [Los Alamos National Laboratory; Chung, Kiwhan [Los Alamos National Laboratory; Clark, Deborah J [Los Alamos National Laboratory; Green, Jesse A [Los Alamos National Laboratory; Greene, Steven J [Los Alamos National Laboratory; Hogan, Gary E [Los Alamos National Laboratory; Jason, Andrew [Los Alamos National Laboratory; Lisowski, Paul W [Los Alamos National Laboratory; Makela, Mark F [Los Alamos National Laboratory; Mariam, Fessaha G [Los Alamos National Laboratory; Miyadera, Haruo [Los Alamos National Laboratory; Murray, Matthew M [Los Alamos National Laboratory; Saunders, Alexander [Los Alamos National Laboratory; Wysocki, Frederick J [Los Alamos National Laboratory; Gray, Frederick E [REGIS UNIV.

    2010-01-01

    A segmented neutron calorimeter using nine 4-inch x 4-inch x 48-inch plastic scintillators and sixteen 2-inch-diameter 48-inch-long 200-mbar-{sup 3}He drift tubes is described. The correlated scintillator and neutron-capture events provide a means for n/{gamma} discrimination, critical to the neutron calorimetry when the {gamma} background is substantial and the {gamma} signals are comparable in amplitude to the neutron signals. A single-cell prototype was constructed and tested. It can distinguish between a {sup 17}N source and a {sup 252}Cf source when the {gamma} and the thermal neutron background are sufficiently small. The design and construction of the nine-cell segmented detector assembly follow the same principle. By recording the signals from individual scintillators, additional {gamma}-subtraction schemes, such as through the time-of-flight between two scintillators, may also be used. The variations of the light outputs from different parts of a scintillator bar are less than 10%.

  18. Neutral beam injection in a D-{sup 3}He FRC reactor

    Energy Technology Data Exchange (ETDEWEB)

    Ferrari, Hugo; Farengo, Ricardo [Centro Atomico Bariloche (CNEA) and Instituto Balseiro (UNC-CNEA) 8400 S. C. de Bariloche, RN (Argentina)

    2007-06-15

    The use of neutral beam injection (NBI) to sustain a fraction of the plasma current in a field reversed configuration (FRC) reactor operating with the D-{sup 3}He reaction is studied. A Monte Carlo code already used to study NBI in medium size FRCs is employed (Lifschitz A F, Farengo R and Arista N R 2002 Nucl. Fusion 42 863, Lifschitz A F, Farengo R and Arista N R 2002 Plasma Phys. Control. Fusion 44 1979, Lifschitz A F, Farengo R and Hoffman A L 2004 Nucl. Fusion 44 1015) and the plasma parameters are similar to those proposed in the ARTEMIS (Momota H, Ishida A, Kohzaki Y, Miley G, Ohi S, Ohnishi M, Sato K, Steinhauer L, Tomita Y and Tuszewki M 1992 Fusion Technol. 21 2307) conceptual reactor design. A simple analysis shows that the driven current cannot reach the values quoted in the ARTEMIS project and a procedure to search for plasma parameters that result in higher efficiencies is presented.

  19. Dispersion induced splitting of the collective mode spectrum in A-phase of superfluid 3He

    Science.gov (United States)

    Brusov, Peter; Brusov, Pavel

    2009-05-01

    The whole collective mode spectrum in A-phase of superfluid 3He with dispersion corrections is calculated. The degeneracy of clapping-modes depends on the direction of the collective mode momentum k with respect to the vector l (mutual orbital moment of Cooper pairs), namely: the mode degeneracy remains the same as in case of zero momentum k for k∥l only. For any other directions there is a three-fold splitting of these modes, which reaches maximum for k⊥l. The obtained results means that new interesting features can be observed in ultrasound experiments in axial-phase: the change of the number of peaks in ultrasound absorption into clapping-mode. Single peak, observed for these modes in axial-phase by Ling et al. [R. Ling, W. Wojtanowski, J. Saunders, E.R. Dobbs, J. Low Temp. Phys. 78 (1990) 187] will split into three peaks under change the ultrasound direction with respect to the vector l.

  20. 3He/4He Ratio in Olivines from Linosa, Ustica, and Pantelleria Islands (Southern Italy

    Directory of Open Access Journals (Sweden)

    Elise Fourré

    2012-01-01

    Full Text Available We report helium isotope data for 0.03–1 Ma olivine-bearing basaltic hawaiites from three volcanoes of the southern Italy magmatic province (Ustica, Pantelleria, and Linosa Islands. Homogenous 3He/4He ratios (range: 7.3–7.6 Ra for the three islands, and their similarity with the ratio of modern volcanic gases on Pantelleria, indicate a common magmatic end-member. In particular, Ustica (7.6±0.2 Ra clearly differs from the nearby Aeolian Islands Arc volcanism, despite its location on the Tyrrhenian side of the plate boundary. Although limited in size, our data set complements the large existing database for helium isotope in southern Italy and adds further constraints upon the spatial extent of intraplate alkaline volcanism in southern Mediterranea. As already discussed by others, the He-Pb isotopic signature of this magmatic province indicates a derivation from a mantle diapir of a OIB-type that is partially diluted by the depleted upper mantle (MORB mantle at its periphery.

  1. Progression of emphysema in a 12-month hyperpolarized 3He-MRI study: lacunarity analysis provided a more sensitive measure than standard ADC analysis

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva;

    2009-01-01

    subject was imaged at two lung volumes: functional residual capacity (FRC) and FRC plus 15% of total lung capacity. Means and standard deviations of apparent diffusion coefficients (ADCs) were calculated from coronal images of the entire lung and correlated with pulmonary function test results...

  2. Search for the 4He-eta bound state in dd->(4He-eta)_{bound}->3He n pi0 and dd->(4He-eta)_{bound}->3He p pi- reactions with the WASA-at-COSY facility

    CERN Document Server

    Skurzok, M; Moskal, P

    2014-01-01

    In November 2010, the search for the 4He-{\\eta} bound state was per formed with high statistics and high acceptance with the WASA-at-COSY facility using a ramped beam technique. The signature of eta - mesic nuclei is searched for in the measured excitation functions for the two reaction channels: dd ->3He n pi0 and dd ->3He p pi- near the eta production threshold. This report includes the description of the experimental method and the status of the data analysis.

  3. Diffusion coefficient in photon diffusion theory

    NARCIS (Netherlands)

    Graaff, R; Ten Bosch, JJ

    2000-01-01

    The choice of the diffusion coefficient to be used in photon diffusion theory has been a subject of discussion in recent publications on tissue optics. We compared several diffusion coefficients with the apparent diffusion coefficient from the more fundamental transport theory, D-app. Application to

  4. Orientation-Dependent 3He Lung Imaging in an Open Access, Very-Low-Field Human MRI System

    CERN Document Server

    Mair, R W; Patz, S; Rosen, M S; Ruset, I C; Topulos, G P; Tsai, L L; Butler, J P; Hersman, F W; Walsworth, R L

    2004-01-01

    Orientation-dependent imaging of human lungs is demonstrated using inhaled laser-polarized 3He gas and an open-access very-low-magnetic field (< 5 mT) MRI instrument. This prototype device employs a simple, low-cost electromagnet, with an open geometry that allows variation of the orientation of the imaging subject in a two-dimensional plane. Two-dimensional 3He images were acquired with 2 mm in-plane resolution from a subject in two orientations: lying supine, and sitting in a vertical position with one arm raised. The images show clear differences in lung shape and inhaled 3He gas distribution, consistent with the expected orientation dependence of pulmonary physiology.

  5. An experimental study of the reaction p + d → 3He + π0 in the Δ(1236) resonance region

    International Nuclear Information System (INIS)

    The differential cross section of the reaction p + d → 3He + π0 was measured at an incident proton energy of 462 MeV for 3He cm angles between 50 and 1300. Limited angular distributions were also obtained at 377 and 576 MeV. The 3He particle momentum was measured by using wire spark chambers in conjunction with a total energy absorption scintillation counter. A decay photon from the π0 was detected in a lead glass Cherenkov counter. The results are discussed in terms of a two-nucleon model and a OPE model of the reaction. The cross section at 462 MeV is also compared with that of its isospin conjugate reaction, p + d → 3H + π+, and agreement with the principle of isospin invariance is satisfactory, except at small pion angles. (U.S.)

  6. Reaction mechanism and characteristics of $T_{20}$ in $d + ^3He$ backward elastic scattering at intermediate energies

    CERN Document Server

    Tanifuji, M; Iseri, Y; Uesaka, T; Sakamoto, N; Satou, Y; Itoh, K; Sakai, H; Tamii, A; Ohnishi, T; Sekiguchi, K; Yako, K; Sakoda, S; Okamura, H; Suda, K; Wakasa, T

    2000-01-01

    For backward elastic scattering of deuterons by ^3He, cross sections \\sigma and tensor analyzing power T_{20} are measured at E_d=140-270 MeV. The data are analyzed by the PWIA and by the general formula which includes virtual excitations of other channels, with the assumption of the proton transfer from ^3He to the deuteron. Using ^3He wave functions calculated by the Faddeev equation, the PWIA describes global features of the experimental data, while the virtual excitation effects are important for quantitative fits to the T_{20} data. Theoretical predictions on T_{20}, K_y^y (polarization transfer coefficient) and C_{yy} (spin correlation coefficient) are provided up to GeV energies.

  7. Threshold groundwater ages and young water fractions estimated from 3H, 3He, and 14C

    Science.gov (United States)

    Kirchner, James; Jasechko, Scott

    2016-04-01

    It is widely recognized that a water sample taken from a running stream is not described by a single age, but rather by a distribution of ages. It is less widely recognized that the same principle holds true for groundwaters, as indicated by the commonly observed discordances between model ages obtained from different tracers (e.g., 3H vs 14C) in the same sample. Water age distributions are often characterized by their mean residence times (MRT's). However, MRT estimates are highly uncertain because they depend on the shape of the assumed residence time distribution (in particular on the thickness of the long-time tail), which is difficult or impossible to constrain with data. Furthermore, because MRT's are typically nonlinear functions of age tracer concentrations, they are subject to aggregation bias. That is, MRT estimates derived from a mixture of waters with different ages (and thus different tracer concentrations) will systematically underestimate the mixture's true mean age. Here, building on recent work with stable isotope tracers in surface waters [1-3], we present a new framework for using 3H, 3He and 14C to characterize groundwater age distributions. Rather than describing groundwater age distributions by their MRT, we characterize them by the fraction of the distribution that is younger or older than a threshold age. The threshold age that separates "young" from "old" water depends on the characteristics of the specific tracer, including its history of atmospheric inputs. Our approach depends only on whether a given slice of the age distribution is younger or older than the threshold age, but not on how much younger or older it is. Thus our approach is insensitive to the tails of the age distribution, and is therefore relatively unaffected by uncertainty in the distribution's shape. Here we show that concentrations of 3H, 3He, and 14C are almost linearly related to the fractions of water that are younger or older than specified threshold ages. These

  8. 3 He Co-magnetometer Readout for the SNS nEDM Experiment

    Science.gov (United States)

    Kim, Young Jin; Clayton, Steven

    2014-09-01

    A search for a permanent electric dipole moment (EDM) of the neutron would provide one of the most important low energy tests of the discrete symmetries beyond the Standard Model of particle physics. A new experimental search of neutron EDM, to be conducted at the Spallation Neutron Source (SNS) at ORNL, has been proposed with a goal of 100-fold improvement in the present experimental limit of 10-26e .cm The experiment is based on the magnetic-resonance technique in which polarized neutrons precess at the Larmor frequency when placed in a static magnetic field; a non-zero EDM would be evident as a difference in precession frequency when a strong electric field is applied parallel vs. anti-parallel to the magnetic field. In addition to its role as neutron spin-analyzer via the spin-dependent n+3He nuclear capture process, polarized helium-3 (which has negligible EDM) will serve as co-magnetometer to correct for drifts in the magnetic field. The helium-3 co-magnetometer will be directly read out by superconducting gradiometers coupled to SQUIDs. We describe a proposed SQUID system suitable for the complex neutron EDM apparatus, and demonstrate that the field noise in the SQUID system, tested in an environment similar to the EDM apparatus, meets the nEDM requirement. We also present a test of the compatibility of low-noise SQUID operation with other devices, potential sources of electromagnetic interference, which are necessarily operating during the EDM measurement period and effective ambient magnetic field noise cancellation with an implementation of reference channels.

  9. Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis

    Directory of Open Access Journals (Sweden)

    Jean-Philippe Lanoix

    2015-06-01

    Full Text Available Mice are the most commonly used species for non-clinical evaluations of drug efficacy against tuberculosis (TB. Unlike commonly used strains, C3HeB/FeJ mice develop caseous necrosis in the lung, which might alter the representation of drug efficacy in a way that is more like human TB. Because the development of such pathology requires time, we investigated the effect of infection incubation period on the activity of six drugs in C3HeB/FeJ and BALB/c mice. Mice were aerosol infected and held for 6, 10 or 14 weeks before receiving therapy with rifampin (RIF, rifapentine (RPT, pyrazinamide (PZA, linezolid (LZD, sutezolid (PNU or metronidazole (MTZ for 4-8 weeks. Outcomes included pathological assessments, pH measurements of liquefied caseum and assessment of colony-forming unit (CFU counts from lung cultures. Remarkable heterogeneity in the timing and extent of disease progression was observed in C3HeB/FeJ mice, largely independent of incubation period. Likewise, drug efficacy in C3HeB/FeJ mice was not affected by incubation period. However, for PZA, LZD and PNU, dichotomous treatment effects correlating with the presence or absence of large caseous lesions were observed. In the case of PZA, its poor activity in the subset of C3HeB/FeJ mice with large caseous lesions might be explained by the pH of 7.36±0.09 measured in liquefied caseum. This study highlights the potential value of C3HeB/FeJ mice for non-clinical efficacy testing, especially for investigating the interaction of lesion pathology and drug effect. Careful use of this model could enhance the bridging of non-clinical results with clinical outcomes.

  10. Study of the {sup 3} He(d, p){sup 4} He reaction through the Trojan Horse Method

    Energy Technology Data Exchange (ETDEWEB)

    La Cognata, M. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, Catania (Italy); Dipartimento di Metodologie Chimiche e Fisiche per l' Ingegneria, Universita di Catania (Italy); Musumarra, A. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, Catania (Italy); Dipartimento di Metodologie Chimiche e Fisiche per l' Ingegneria, Universita di Catania (Italy); Spitaleri, C. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, Catania (Italy); Dipartimento di Metodologie Chimiche e Fisiche per l' Ingegneria, Universita di Catania (Italy)] (and others)

    2005-07-25

    The astrophysically relevant {sup 3} He(d, p){sup 4} He reaction was indirectly studied by means of the Trojan Horse Method applied to the {sup 6} Li({sup 3} He, p{alpha}){sup 4} He three body process performed at 5 and 6 MeV. The bare astrophysical S(E)-factor extracted in Modified Plane Wave Born Approximation was compared with the free behaviour and an independent estimate of the screening potential was obtained, confirming the discrepancy with the adiabatic limit.

  11. Activation measurement of the 3He(a,g)7Be reaction cross section at high energies

    CERN Document Server

    Bordeanu, C; Halász, Z; Szücs, T; Kiss, G G; Elekes, Z; Farkas, J; Fülöp, Zs; Somorjai, E; 10.1016/j.nuclphysa.2013.03.012

    2013-01-01

    The astrophysically important 3He(a,g)7Be reaction was studied at high energies where the available experimental data are in contradiction. A thin window 3He gas cell was used and the cross section was measured with the activation method. The obtained cross sections at energies between Ec.m. = 1.5 and 2.5 MeV are compared with the available data and theoretical calculations. The present results support the validity of the high energy cross section energy dependence observed by recent experiments.

  12. Geometrical aspects of reaction cross sections for {sup 3}He, {sup 4}He and {sup 12}C projectiles

    Energy Technology Data Exchange (ETDEWEB)

    Ingemarsson, A. [Uppsala Univ. (Sweden). Dept. of Radiation Sciences; Lantz, M. [Uppsala Univ. (Sweden). The Svedberg Laboratory

    2003-04-01

    A black-disc model combined with accurate matter densities has been used for an investigation of reaction cross sections for {sup 3}He, {sup 4}He and {sup 12}C projectiles. A simple relation is derived between the energy dependence of the reaction cross sections and the strength of the nucleon-nucleon interaction. A comparison is also made of the reaction cross sections for {sup 3}He and {sup 4}He for six different nuclei {sup 12}C, {sup 16}O, {sup 40}Ca, {sup 58,60}Ni and {sup 208}Pb.

  13. 正常中老年人群颅脑表观弥散系数特点分析%Apparent diffusion coefficient measurement of brain tissue in normal middle-aged and aged adults

    Institute of Scientific and Technical Information of China (English)

    杨运俊; 郭献忠; 高凌云; 郭翔; 付军; 陈伟建

    2013-01-01

    Objective To investigate the variability and trends of apparent diffusion coefficient (ADC) of different brain segments in normal middle- aged and aged Han adults. Methods Thirty Han normal adult subjects aged 40~70 without positive cerebral symptoms were divided into 3 age groups (40~49, 50~59, 60~70). Plain scan and diffusion weighted imaging (DWI) were performed by 3.0T MR in al subjects. The images were transferred to ADW 4.3 workstations for post- processing. Regions of interest were placed covering grey and white matter of frontal lobe, putamen, thalamus and cerebel um. The relationship of ADC value with different ages and cerebral regions was analyzed. Results The cerebral tissues of different location had differ-ent values in the same age group. The highest ADC value was detected in gray matter of the frontal lobe, fol owed by putamen, white matter of frontal lobe and the thalamus, and the lowest one was in cerebel um. There was no significant difference in ADCs between two sides of the same cerebral parts of different regions.(P>0.05).Although there was no significant difference in ADCs between grey and white matter of frontal lobe, putamen, thalamus and cerebel um of different age groups, the ADC value of the same region tended to increase with age. The changes of ADC value in subjects aged 40~60 presented a much slower rate and an upshift tendency was observed in subjects aged>60. Conclusion The ADC value of the same region in middle- aged and elderly people tended to increase with the age, particularly in subjects aged>60 years.%目的:探讨40~70岁年龄段正常汉族人颅脑各区域磁共振表观弥散系数(ADC)变化特点,建立正常中老年人群颅脑ADC值变化趋势的基准。方法选择30例无阳性颅脑病征的正常汉族受试者,按年龄段分为3组,使用GE Medical System 3.0 T超导磁共振扫描仪进行头部平扫及弥散加权成像,测量额叶灰质、白质、壳核、丘脑及小脑感兴趣区

  14. Apparent Superluminal Behavior

    CERN Document Server

    Jackson, A D; Lautrup, B

    2000-01-01

    The apparent superluminal propagation of electromagnetic signals seen in recent experiments is shown to be the result of simple and robust properties of relativistic field equations. Although the wave front of a signal passing through a classically forbidden region can never move faster than light, an attenuated replica of the signal is reproduced ``instantaneously'' on the other side of the barrier. The reconstructed signal, causally connected to the forerunner rather than the bulk of the input signal, appears to move through the barrier faster than light.

  15. Precise Tests of Fundamental Symmetries at Low Energies using a 3He-129Xe Comagnetometer

    OpenAIRE

    Allmendinger, Fabian

    2015-01-01

    Effects of theories beyond the Standard Model would become directly apparent at high energies, which are probably out of reach for colliders. As an alternative, low-energy high-precision measurements of quantities are performed, looking for deviations from the Standard Model (SM) predictions. In this case: Firstly, a small amount of the large effects of quantum gravity at the Planck scale should remain at low energies, which is tested by looking for Lorentz invariance violation in the neut...

  16. 双指数表观弥散系数对颈内动脉狭窄者大脑的评价%Biexponential apparent diffusion coefficients in brain with stenosis of internal carotid artery

    Institute of Scientific and Technical Information of China (English)

    彭雯佳; 陆建平; 王敏杰; 金爱国; 方亮; 陈士跃; 黄挺

    2013-01-01

    Objective To compare the differences of parameters of diffusion weighted imaging (DWI) with both biexponential and monocxponcntial model between affected and opposite cerebral hemisphere in patients with unilateral stenosis of internal carotid artery (ICA). Methods From June to August, 2011 , patients who had no stenosis artcriostcnosis or had only unilateral stenosis of ICA which diagnosed by CTA, and had no MR imaging contraindication and signed the informed consent underwent DWI at both biexponential and monocxponcntial decay model, the b-valucs were 0, 5, 10, 20, 50, 100, 200, 400, 600, 1000, 1500, 2000, 3000 s/mm2. Then apparent diffusion coefficients (ADCs) of Monocxponcntial model, and Fast ADCs, Slow ADCs, Fraction of Fast ADCs of bi-cxponcntial model were calculated through workstation. According to the stcnotic degrees of ICA, patients were divided as following three groups: no stcnotic group, mild/moderate stcnotic group, and severe stcnotic/occlusivc group. Every parameters of both cerebral side in every groups were calculated, and compared the differences among groups by using Kruskal-Wallis statistic for Wilcoxon rank sum test. Results Fifty-two patients were enrolled in our study, among whom 10 cases in no stcnotic group, 23 cases in mild/moderate stcnotic group, and 19 cases in severe stcnotic/occlusivc group. In the patients with ICA stenosis, Monocxponcntial ADC, Fast ADC and Slow ADC on the affected sides were higher than that in the opposite sides. The differences between affected and opposite side of Monocxponcntial ADC and Slow ADC increased along with the severity of ICA stenosis, and the differences among groups had statistical significance (P = 0. 0046 and P = 0. 0054 ). The absolute different value of Fast ADC in bilateral was highest in no stcnotic group, followed by severe stcnotic/occlusivc group and mild/moderate stcnotic group, there was no of statistical significance between group ( P = 0. 0368 ). The differences of fraction of Fast

  17. Experimental resolution of deuterium and hydrogen depth profiling with the nuclear reactions D(3He,p)α and p(15N,α,γ)12C

    International Nuclear Information System (INIS)

    In this paper well defined test samples are used to show how the analysis depth and the matrix material influence the depth resolution of nuclear reaction analysis. The reaction D(3He,p)α is used to detect deuterium. By covering 10 nm thin deuterated amorphous carbon (a–C:D) films on silicon with tungsten (ZW = 74) and titanium (ZTi = 22) of various thicknesses between 500 nm and 8 μm the influence of the atomic number and the overlayer thickness on the depth resolution is studied. The most probable depth profiles are calculated from the experimental data with the program NRADC, which implements Bayesian statistics. The resulting apparent layer width of the deuterium containing layer broadens with increasing thickness of the coating and this broadening is more pronounced for coatings with higher Z. These apparent layer widths are a measure for the experimentally achievable depth resolution. Their absolute values are in the same range as the theoretical optimum calculated with RESOLNRA. To investigate the depth resolution of the p(15N,α,γ)12C reaction, a 12 nm thin hydrogenated amorphous carbon (a–C:H) film on silicon and a pure tungsten sample are analysed. The width of the instrument function of this method is deduced from the surface hydrogen peak of the pure tungsten sample. The two methods are compared

  18. The CREp program, a fully parameterizable program to compute exposure ages (3He, 10Be)

    Science.gov (United States)

    Martin, L.; Blard, P. H.; Lave, J.; Delunel, R.; Balco, G.

    2015-12-01

    Over the last decades, cosmogenic exposure dating permitted major advances in Earth surface sciences, and particularly in paleoclimatology. Yet, exposure age calculation is a dense procedure. It requires numerous choices of parameterization and the use of an appropriate production rate. Nowadays, Earth surface scientists may either calculate exposure ages on their own or use the available programs. However, these programs do not offer the possibility to include all the most recent advances in Cosmic Ray Exposure (CRE) dating. Notably, they do not propose the most recent production rate datasets and they only offer few possibilities to test the impact of the atmosphere model and the geomagnetic model on the computed ages. We present the CREp program, a Matlab © code that computes CRE ages for 3He and 10Be over the last 2 million years. The CREp program includes the scaling models of Lal-Stone in the "Lal modified" version (Balco et al., 2008; Lal, 1991; Stone, 2000) and the LSD model (Lifton et al., 2014). For any of these models, CREP allows choosing between the ERA-40 atmosphere model (Uppala et al., 2005) and the standard atmosphere (National Oceanic and Atmospheric Administration, 1976). Regarding the geomagnetic database, users can opt for one of the three proposed datasets: Muscheler et al. 2005, GLOPIS-75 (Laj et al. 2004) and the geomagnetic framework proposed in the LSD model (Lifton et al., 2014). They may also import their own geomagnetic database. Importantly, the reference production rate can be chosen among a large variety of possibilities. We made an effort to propose a wide and homogenous calibration database in order to promote the use of local calibration rates: CREp includes all the calibration data published until July 2015 and will be able to access an updated online database including all the newly published production rates. This is crucial for improving the ages accuracy. Users may also choose a global production rate or use their own data

  19. Adsorbed Layers of D2, H2, O2, and 3He on Graphite Studied by Neutron Scattering

    DEFF Research Database (Denmark)

    Nielsen, Mourits; McTague, J. P.; Ellenson, W. D.

    1977-01-01

    The phase diagrams of adsorbed monolayers of D2, H2, O2, and 3He on graphite have been measured by neutron diffraction. H2 and D2-layers have a registered √3 structure at low coverages, and at monolayer completion they have a dense triangular structure, which is incommensurate with the substrate...

  20. A High-Pressure Polarized $^3$He Gas Target for Nuclear Physics Experiments Using A Polarized Photon Beam

    CERN Document Server

    Ye, Q; Chen, W; Gao, H; Zheng, W; Zong, X; Averett, T; Cates, G D; Tobias, W A

    2009-01-01

    Following the first experiment on three-body photodisintegration of polarized $^3$He utilizing circularly polarized photons from High Intensity Gamma Source (HI$\\gamma$S) at Duke Free Electron Laser Laboratory (DFELL), a new high-pressure polarized $^3$He target cell made of pyrex glass coated with a thin layer of sol-gel doped with aluminum nitrate nonahydrate has been built in order to reduce photon beam induced backgrounds. The target is based on the technique of spin-exchange optical pumping of hybrid rubidium and potassium and the highest polarization achieved is $\\sim$62\\% determined from both NMR-AFP and EPR polarimetry. The $X$ parameter is estimated to be $0.17\\pm0.06$ and the performance of the target is in good agreement with theoretical predictions. We also present beam test results from this new target cell and the comparison with the GE180 $^3$He target cell used previously at HI$\\gamma$S. This is the first time that sol-gel coating technique has been used in a polarized $^3$He target for nuclea...

  1. Two-dimensional and three-dimensional oxygen mapping by 3He-MRI validation in a lung phantom

    International Nuclear Information System (INIS)

    The aim of this study was to validate oxygen-sensitive 3He-MRI in noninvasive determination of the regional, two- and three-dimensional distribution of oxygen partial pressure. In a gas-filled elastic silicon ventilation bag used as a lung phantom, oxygen sensitive two- and three-dimensional 3He-MRI measurements were performed at different oxygen concentrations which had been equilibrated in a range of normal and pathologic values. The oxygen partial pressure distribution was determined from 3He-MRI using newly developed software allowing for mapping of oxygen partial pressure. The reference bulk oxygen partial pressure inside the phantom was measured by conventional respiratory gas analysis. In two-dimensional measurements, image-based and gas-analysis results correlated with r=0.98; in three-dimensional measurements the between-methods correlation coefficient was r=0.89. The signal-to-noise ratio of three-dimensional measurements was about half of that of two-dimensional measurements and became critical (below 3) in some data sets. Oxygen-sensitive 3He-MRI allows for noninvasive determination of the two- and three-dimensional distribution of oxygen partial pressure in gas-filled airspaces. (orig.)

  2. The apparent Universe

    Science.gov (United States)

    Binétruy, P.; Helou, A.

    2015-10-01

    We exploit the parallel between dynamical black holes and cosmological spacetimes to describe the evolution of Friedmann-Lemaître-Robertson-Walker universes from the point of view of an observer in terms of the dynamics of the apparent horizon. Using the Hayward-Kodama formalism of dynamical black holes, we clarify the role of the Clausius relation to derive the Friedmann equations for a Universe, in the spirit of Jacobson’s work on the thermodynamics of spacetime. We also show how dynamics at the horizon naturally leads to the quantum-mechanical process of Hawking radiation. We comment on the connection of this work with recent ideas to consider our observable Universe as a Bose-Einstein condensate and on the corresponding role of vacuum energy.

  3. A survey of 3He enhancements at 2–20 MeV/nucleon: Ulysses COSPIN/LET

    Directory of Open Access Journals (Sweden)

    M. Y. Hofer

    Full Text Available We present the results of a survey of enhancements in the ratio of 3He/4 He as measured by the COSPIN/LET instrument on board the Ulysses spacecraft in the energy range 2–20 MeV/n. In the context of this study, all ratios of 3He/4 He above 0.05 are considered to be enhanced compared with the solar system value of ~0.0004. Previous studies have shown that enhanced fluxes of 3He are frequently associated with small, impulsive solar flare events in which the observer is well connected to the flare site. These events also often show enrichments in heavy ion composition compared with standard coronal values. Recent attention has also focused on 3He enrichments as evidence for re-acceleration of remnant particle populations that are present in the inner heliosphere following periods of enhanced solar activity. For this study, we have examined the Ulysses data set from launch (October 1990 up to the present, representing a full solar cycle. The spatial coverage extends from 1–5.4 AU in heliocentric distance, and effectively includes the complete range of heliomagnetic latitudes from pole to pole. We have identified 12 periods of enhanced 3He/4 He, occurring at heliocentric distances out to 5 AU, and heliolatitudes up to 48°. We investigate the characteristics of the events, many of which last for several days, in order to establish possible origins.Key words. Interplanetary physics (energetic particles – Solar physics, astrophysics and astronomy (energetic particles; flares and mass ejections

  4. A software tool for analysis and quantification of regional pulmonary ventilation using dynamic hyperpolarised-3He-MRI

    International Nuclear Information System (INIS)

    Purpose: 3He-MRI is able to visualize the regional distribution of lung ventilation with a temporal and spatial resolution so far unmatched by any other technique. The main of the study was the development of a new software tool for quantification of dynamic ventilation parameters in absolute physical units. Materials and Methods: During continuous breathing, a bolus of hyperpolarized 3He (300 ml) was applied at inspiration and a series of 168 coronal projection images simultaneously acquired using a 2D FLASH-sequence. Postprocessing software was developed to analyze the 3He distribution in the lung. After correction for lung motion, several ventilation parameters (rise time, delay time, 3He amount and 3He peak flow) were calculated. Due to normalization of signal intensities, these parameters are presented in absolute physical units. The data sets were analyzed on a ROI basis as well as on a pixel-by-pixel basis. Results: Using the developed software, the measurements were analyzed in 6 lung-healthy volunteers, in one patient after lung transplantation, and in one patient with lung emphysema. The volunteers' parameter maps of the pixel-based analysis showed an almost homogeneous distribution of the ventilation parameters within the lung. In the parameter maps of both patients, regions with poor ventilation were observed. Conclusion: The developed software permits an objective and quantitative analysis of regional lung ventilation in absolute physical units. The clinical significance of the parameters, however, has to be determined in larger clinical studies. The software may become valuable in grading and following pulmonary function as well as in monitoring any therapy. (orig.)

  5. The development of {sup 3}He neutron detectors for applications in high level gamma-ray backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Menlove, H.O.; Beddingfield, D.H.

    1995-12-01

    To measure high-level-activity scrap and waste, it is necessary to use neutron detectors that are insensitive to the high gamma-ray background. We have developed a combination of {sup 3}He tubes and custom preamplifiers to provide the high efficiency associated with {sup 3}He detectors with good gamma-ray rejection. We have preamplifiers with short time constants in the signal processing to help separate the neutron signals from the slower risetime gamma signals. We have compared AMPTEK (A-111) preamplifiers with Precision Data Technology (PDT 110A) preamplifiers with experimental tests for gamma rejection and radiation damage. Hot cell radiation tests using a 4.5 Ci radium source were performed using {sup 10}B and {sup 3}He detectors to evaluate relative efficiency and the ability to separate neutrons and gamma rays. The AMPTEK A-111 and PDT-110A amplifiers were exposed to gamma doses between {approximately}0.1 R/h and 1500 R/h to observe where the gamma pileup would interfere with the neutron counting. The conclusion is that both amplifiers can operate in gamma fields up to {approximately}500 R/h with modest loss of neutron efficiency. This is valid for the case of only one {sup 3}He tube (30-cm active length) connected to a single amplifier. If an amplifier services multiple tubes or longer tubes, the gamma rejection will get worse. Studies are in progress to determine the lifetime of the amplifiers and {sup 3}He tubes in the high-radiation fields.

  6. Evidence for a Common Acceleration Mechanism for Enrichments of 3He and Heavy Ions in Impulsive SEP Events

    Science.gov (United States)

    Mason, Glenn M.; Nitta, Nariaki V.; Wiedenbeck, Mark E.; Innes, Davina E.

    2016-06-01

    We have surveyed the period 1997–2015 for a rare type of 3He-rich solar energetic particle (SEP) event, with enormously enhanced values of the S/O ratio, that differs from the majority of 3He-rich events, which show enhancements of heavy ions increasing smoothly with mass. Sixteen events were found, most of them small but with solar source characteristics similar to other 3He-rich SEP events. A single event on 2014 May 16 had higher intensities than the others, and curved Si and S spectra that crossed the O spectrum above ∼200 keV nucleon‑1. Such crossings of heavy-ion spectra have never previously been reported. The dual enhancement of Si and S suggests that element Q/M ratio is critical to the enhancement since this pair of elements uniquely has very similar Q/M ratios over a wide range of temperatures. Besides 3He, Si, and S, in this same event the C, N, and Fe spectra also showed curved shape and enhanced abundances compared to O. The spectral similarities suggest that all have been produced from the same mechanism that enhances 3He. The enhancements are large only in the high-energy portion of the spectrum, and so affect only a small fraction of the ions. The observations suggest that the accelerated plasma was initially cool (∼0.4 MK) and was then heated to a few million kelvin to generate the preferred Q/M ratio in the range C–Fe. The temperature profile may be the distinct feature of these events that produces the unusual abundance signature.

  7. The Value of Apparent Diffusion Coefficient in Differentiation of Pediatric Posterior Fossa Tumors%表观扩散系数值鉴别儿童后颅窝肿瘤的价值

    Institute of Scientific and Technical Information of China (English)

    季学满; 张宗军; 卢光明; 毕俊; 袁彩云; 王俊鹏; 贾传海

    2011-01-01

    Objective To assess the utility of apparent diffusion coefficient ADC) for differential diagnosis of common pediatric posterior possa tumors. Materials and Methods In 43 pediatric patients with surgically and pathologically confirmed posterior possa tumors, there were 24 medulloblastomas,10 pilocytic astrocytomas,and 9 ependymomas. All pediatric patients recevied conventional MRI,DWI and contrast enhanced MRI examination, the signal intensity of tumor parenchyma was compared with that of normal cerebellar parenchymas. ADC values of tumor parenchyma were measured quantitatively. ADC values of medullohlastomas, pilocytic a8trocytomas,and ependymomas were compared by Wilcoxon rank sum test. Results On ADC map,In 24 patients with medulloblastomas, the tumors showed hypointense in 9 patients, slightly hypointense in 12 patients, and isointense in 3 patients; the average ADC value of tumor parenchymas was (0.70 ±0. II) x 10-3 mm2/s. All tumors showed hyperintense in 10 patients with pilocytic astrocytoma, the average ADC value of tumor parenchymas was (1.80 ±0.30) ×10-3 mm2/s. In 9 patients with ependymomas, the tumors showed slightly hyperintense in 5 patients, hyperintense in 4 patients; the average ADC value of tumor parenchymas was ( 1. 16 ±0.18) ×10-3 mm2/s. The ADC value of medulloblastoma was lower than that of pilocytic astrocytoma, which was statistically significant ( Z = -4. 54, P < 0.01). The ADC value of medulloblastoma was lower than that of ependymoma, which was statistically significant (Z= -4.29,P < 0.01), The ADC value of pilocytic astrocytoma was higher than that of ependymoma,which was statistically significant (Z= -3. 27,P < 0. 05). Conclusion Measurement of ADC value of cerebral tumor parenchyma is a simple and available method, which is useful for preoperative differentiation of pediatric posterior possa tumors, especially in differential diagnosis of medulloblastoma and pilocytic astrocytoma.%目的 评价MRI表观扩散系数(ADC)值在儿

  8. B0-correction and k-means clustering for accurate and automatic identification of regions with reduced apparent diffusion coefficient (ADC) in adva nced cervical cancer at the time of brachytherapy

    DEFF Research Database (Denmark)

    Haack, Søren; Pedersen, Erik Morre; Vinding, Mads Sloth;

    Diffusion weighted MRI has shown great potential in diagnostic cancer imaging and may also have value for monitoring tumor response during radiotherapy. Uncertainties due to geometric distortions caused by B0-inhomogeneity and tumor delineation are major obstacles for implementing DWI for use in ...... of advanced cervical cancer.......Diffusion weighted MRI has shown great potential in diagnostic cancer imaging and may also have value for monitoring tumor response during radiotherapy. Uncertainties due to geometric distortions caused by B0-inhomogeneity and tumor delineation are major obstacles for implementing DWI for use...

  9. Measure of elastic differential cross sections 3He (π±,π±) 3He and 4He (π±,π±) 4He in the 25 to 65 MeV range

    International Nuclear Information System (INIS)

    Measurement of low energy pion elastic differential cross sections on light nuclei 3He and 4He has been made to improve our understanding of pion-nucleus interaction mechanisms. For this purpose, π+ and π- cross sections at 25 and 51 MeV on 4He and 30, 45 and 65 MeV on 3He have been measured for scattering angles between 40 and 140 deg. in the laboratory. The pion flux was known within 2 pc accuracy and low temperature liquid targets were used. The scattered π+ and π- were detected in range spectrometers with 90 pc efficiency and 2 MeV energy resolution. Overall accuracy on the cross section is 5 pc. Comparison with microscopic optical potential calculations shows that much remains to be done to reproduced the measured cross sections. More particularly, Coulomb corrections, binding energy effects of the scattering nucleon and pion absorption should be more realistic to account properly for the data. (author)

  10. 肺癌MR表观弥散系数及最佳b值的初步研究%MR Apparent Diffusion Coefficient and Optimal b Value of Pulmonary Carcinomas:A Preliminary Study

    Institute of Scientific and Technical Information of China (English)

    贺伟; 徐金萍; 谢汝明; 周新华; 吕岩; 宁锋钢

    2014-01-01

    目的 研究肺癌MR表观扩散系数(ADC)的特点,比较不同类型肺癌的ADC值差异,并探讨最佳b值的选择.方法 经临床、穿刺或手术病理证实的44例肺癌,行MRI常规T1WI、T2 WI和DWI扫描(b值为0、500、800、1000 s/mm2);对DWI序列上显示高信号的病灶分别测量并比较不同b值的ADC值,用方差分析比较其差异;采用受试者操作特征曲线(ROC)分析不同b值下ADC值对不同类型肺癌的鉴别诊断效能,选择出最佳b值;在最佳b值下分别对小细胞肺癌及非小细胞肺癌组,中心型肺癌和周围型肺癌组,各种不同类型的肺癌组的ADC值进行比较计算,符合正态分布者以t检验和方差分析进行比较.结果 本组42例肺癌显示高信号,2例腺癌未显示高信号.三种不同b值组的平均ADC值均随b值增加逐渐变小,差异有统计学意义(F=11.606,P=0.000),但b值为800和1000 s/mm2时两者未见显著差异(P =0.164,P>0.05);8组不同类型肺癌的ROC曲线分析显示,三组不同b值下的ADC值比较均有诊断意义(曲线下面积均<0.5),但其中7组以b取800 s/mm2时诊断效能最高,故认为b取800 s/mm2时为最佳;小细胞肺癌、类癌的ADC值高于非小细胞肺癌(P =0.046,P<0.05;P =0.073;P<0.1),腺癌的ADC值明显低于类癌(P=0.042,P<0.05),腺癌的ADC值明显低于小细胞肺癌(P =0.020,P<0.05),鳞癌与类癌略有差异(P =0.103),其他各种类型ADC值未见显著差异(P>0.05).结论 800 s/mm2为最佳b值,ADC值对肺癌的组织学分型有一定意义.%Objective To investigate the characteristics of MR apparent diffusion coefficient (ADC) values of the pulmonary carcinomas,to compare ADC values between the different types of lung carcinomas,and to discuss the optimal b value.Methods A total of 44 patients with pathologically-proved lung cancer were enrolled in this study.Conventional MRI T1 WI and T2WI as well as DWI (b value =0,500,800 and 1000 s/mm2) was performed in all patients.ADC values

  11. Comparison of Thermal Neutron Detection Efficiency of $^{6}$Li Scintillation Glass and $^{3}$He Gas Proportional Tube

    CERN Document Server

    Xu, Ming; Chen, Guo-Ming; Tao, Jun-Quan

    2013-01-01

    We report on a comparison study of the $^{3}$He gas proportional tube and the $^{6}$Li incorporated scintillation glasses on thermal neutron detection efficiency. Both $^{3}$He and $^{6}$Li are used commonly for thermal neutron detection because of their high neutron capture absorption coefficient. By using a neutron source $^{252}$Cf and a paraffin moderator in an alignment system, we can get a small beam of thermal neutrons. A flash ADC is used to measure the thermal neutron spectrum of each detector, and the detected number of events is determined from the spectrum, then we can calculate the detection efficiency of different detectors. Meanwhile, the experiment have been modeled with GEANT4 to validate the results against the Monte Carlo simulation.

  12. Experimental study of the p d (d p )→3Heπ π reactions close to threshold

    Science.gov (United States)

    Bellemann, F.; Berg, A.; Bisplinghoff, J.; Bohlscheid, G.; Ernst, J.; Henrich, C.; Hinterberger, F.; Ibald, R.; Jahn, R.; Joosten, R.; Kilian, K.; Kozela, A.; Machner, H.; Magiera, A.; Munkel, J.; von Neumann-Cosel, P.; von Rossen, P.; Schnitker, H.; Scho, K.; Smyrski, J.; Tölle, R.; Wilkin, C.; COSY-MOMO Collaboration

    2016-09-01

    New experimental data on the p d → 3Heπ+π- reaction obtained with the COSY-MOMO detector below the three-pion threshold are presented. The reaction was also studied in inverse kinematics with a deuteron beam and the higher counting rates achieved were especially important at low excess energies. The comparison of these data with inclusive p d → 3HeX0 rates allowed estimates also to be made of π0π0 production. The results confirm our earlier findings that, close to threshold, there is no enhancement at low excitation energies in the π+π- system, where the data seem largely suppressed compared with phase space. Possible explanations for this behavior, such as strong p waves in the π+π- system or the influence of two-step processes, are explored.

  13. Low-energy effective field theory of superfluid 3He-B and its gyromagnetic and Hall responses

    CERN Document Server

    Fujii, Keisuke

    2016-01-01

    The low-energy physics of a superfluid 3He-B is governed by Nambu-Goldstone bosons resulting from its characteristic symmetry breaking pattern. Here we construct an effective field theory at zero temperature consistent with all available symmetries in curved space, which are the U(1) phase x SU(2) spin x SO(3) orbital gauge invariance and the nonrelativistic general coordinate invariance, up to the next-to-leading order in a derivative expansion. The obtained low-energy effective field theory is capable of predicting gyromagnetic responses of the superfluid 3He-B, such as a magnetization generated by a rotation and an orbital angular momentum generated by a magnetic field, in a model-independent and nonperturbative way. We furthermore show that the stress tensor exhibits a dissipationless Hall viscosity with coefficients uniquely fixed by the orbital angular momentum density, which manifests itself as an elliptical polarization of sound wave with an induced transverse component.

  14. Comparison of thermal neutron detection efficiency of 6Li scintillation glass and 3He gas proportional tube

    International Nuclear Information System (INIS)

    We report on a comparison study of the 3He gas proportional tube and the 6Li incorporated scintillation glasses on thermal neutron detection efficiency. Both 3He and 6Li are used commonly for thermal neutron detection because of their high neutron capture absorption coefficient. By using a neutron source 252Cf and a paraffin moderator in an alignment system, we can get a small beam of thermal neutrons. A flash ADC is used to measure the thermal neutron spectrum of each detector, and the detected number of events is determined from the spectrum, then we can calculate the detection efficiency of different detectors. Meanwhile, the experiment has been modeled with GEANT4 to validate the results against the Monte Carlo simulation. (authors)

  15. Non-singlet structure function of the 3He-3H system and divergence of the Gottfried integral

    CERN Document Server

    Guzey, V; Strikman, M I; Thomas, A W; Tsushima, K

    2001-01-01

    We study shadowing and antishadowing corrections to the flavor non-singlet structure function F_2(3He)-F_2(3H) and show that the difference between the one-particle density distributions of 3He and 3H plays an important role at very small x. We find that the flavor non-singlet structure function in these mirror nuclei is enhanced at small x by nuclear shadowing, which increases the nuclear Gottfried integral, integrated from 10^{-4} to 1, by 11-36 %. When integrated from zero, the Gottfried integral is divergent for these mirror nuclei. It seems likely that, as a consequence of charge symmetry breaking, this may also apply to the proton-neutron system.

  16. Tyree-body mechanisms in the 3^He(e,e'p) reactions at high missing momentum

    CERN Document Server

    Laget, J M

    2004-01-01

    A particular three-body mechanism is responsible for the missing strength which has been reported in $^3$He(e,e$'$p) reactions at missing momentum above 700 MeV/c. It corresponds to the absorption of the virtual photon by a nucleon at rest which subsequently propagates on-shell and emits a meson which is reabsorbed by the pair formed by the two other nucleons. Its amplitude, which is negligible in photon induced reactions as well as in the electro-production of an on-shell meson, becomes maximal in the quasi-free kinematics (X=1). It relates the amplitude of the $^3$He(e,e$'$p)D reaction to the amplitude of $pD$ elastic scattering at backward angles.

  17. Ab Initio Calculations of Differential Cross Sections for Single Charge Transfer in 3He2++4 He Collisions

    Institute of Scientific and Technical Information of China (English)

    WU Yong; YAN Bing; LIU Ling; WANG Jian-Guo

    2007-01-01

    The single charge transfer process in 3 He2+ + 4He collisions is investigated using the quantum-mechanical molecularorbital close-coupling method, in which the adiabatic potentials and radial couplings are calculated by using the ab initio multireference single- and double-excitation configuration interaction methods. The differential cross sections for the single charge transfer are presented at the laboratorial energies E = 6kev and 10keV for the projectile 3He2+. Comparison with the existing data shows that the present results are better in agreement with the experimental measurements than other calculations in the dominant small angle scattering, which is attributed to the accurate calculations of the adiabatic potentials and the radial couplings.

  18. Study of the {sup 6}Li + p → {sup 3}He + {sup 4}He reaction in inverse kinematics

    Energy Technology Data Exchange (ETDEWEB)

    Betsou, C.; Pakou, A.; Aslanoglou, X.; Nicolis, N.G.; Sgouros, O.; Soukeras, V. [The University of Ioannina, Department of Physics and HINP, Ioannina (Greece); Cappuzzello, F. [Laboratori Nazionali del Sud, INFN, Catania (Italy); Universita di Catania, Dipartimento di Fisica e Astronomia, Catania (Italy); Acosta, L. [Universidad Nacional Autonoma de Mexico, Instituto de Fisica, Mexico Distrito Federal (Mexico); INFN, Catania (Italy); Agodi, C.; Carbone, D.; Cavallaro, M.; Di Pietro, A.; Fernandez-Garcia, J.P.; Figuera, P.; Fisichella, M. [Laboratori Nazionali del Sud, INFN, Catania (Italy); Foti, A. [Universita di Catania, Dipartimento di Fisica e Astronomia, Catania (Italy); INFN, Catania (Italy); Keeley, N. [National Centre for Nuclear Research, Otwock (Poland); Marquinez-Duran, G.; Martel, I. [Universidad de Huelva, Departamento de Fisica Aplicada, Huelva (Spain); Mazzocco, M.; Strano, E.; Torresi, D. [Universita di Padova, Departimento di Fisica e Astronomia, Padova (Italy); INFN, Padova (Italy); Pierroutsakou, D. [INFN, Napoli (Italy); Rusek, K. [University of Warsaw, Heavy Ion Laboratory, Warsaw (Poland); Stiliaris, E. [University of Athens, Institute of Accelerating Systems and Applications and Department of Physics, Athens (Greece)

    2015-07-15

    Angular distribution measurements were performed for the {sup 6}Li + p → {sup 3}He + {sup 4}He reaction in inverse kinematics at incident energies of 2.7, 3.3, 4.2 and 4.8 MeV/u. The detection of both recoils ({sup 3}He and {sup 4}He) over the laboratory angle range θ{sub lab} = 16 {sup circle} to 34 {sup circle} allowed the determination of the angular distribution over a wide angular range in the center-of-mass frame (θ{sub c.m.} ∝ 40 {sup circle} to 140 {sup circle}). The results clarify inconsistencies between existing data sets and are consistent with compound nucleus model calculations. (orig.)

  19. Measurements of Correlated Pair Momentum Distributions in {sup 3}He(e,e{prime}pp)n with CLAS

    Energy Technology Data Exchange (ETDEWEB)

    Rustam Niyazov

    2003-05-01

    We have measured the {sup 3}He(e,e{prime}pp)n reaction at 2.2 and 4.4 GeV over a wide kinematic range. The kinetic energy distribution for ''fast'' nucleons (p > 250 MeV/c) peaks where two nucleons each have 20% or less and the third or ''leading'' nucleon carries most of the transferred energy. These fast nucleon pairs (both pp and pn) are back-to-back and carry very little momentum along {rvec q}, indicating that they are spectators. Experimental and theoretical evidence indicates that we have measured NN correlations in {sup 3}He(e,e{prime}pp)n by striking the third nucleon and detecting the spectator correlated pair.

  20. Limit on Lorentz-Invariance- and CPT-Violating Neutron Spin Interactions Using a $^3$He-$^{129}$Xe Comagnetometer

    CERN Document Server

    Allmendinger, Fabian; Heil, Werner; Karpuk, Sergej; Sobolev, Yuri

    2016-01-01

    We performed a search for a Lorentz-invariance- and CPT-violating coupling of the $^3$He and $^{129}$Xe nuclear spins to posited background fields. Our experimental approach is to measure the free precession of nuclear spin polarized $^3$He and $^{129}$Xe atoms using SQUID detectors. As the laboratory reference frame rotates with respect to distant stars, we look for a sidereal modulation of the Larmor frequencies of the co-located spin samples. As a result we obtain an upper limit on the equatorial component of the background field $\\tilde{b}^n_{\\bot}< 8.4 \\cdot 10^{-34}$ GeV (68\\% C.L.). Furthermore, this technique was modified to search for an electric dipole moment (EDM) of $^{129}$Xe.