WorldWideScience

Sample records for 3d high frequency

  1. Volume Attenuation and High Frequency Loss as Auditory Depth Cues in Stereoscopic 3D Cinema

    Science.gov (United States)

    Manolas, Christos; Pauletto, Sandra

    2014-09-01

    Assisted by the technological advances of the past decades, stereoscopic 3D (S3D) cinema is currently in the process of being established as a mainstream form of entertainment. The main focus of this collaborative effort is placed on the creation of immersive S3D visuals. However, with few exceptions, little attention has been given so far to the potential effect of the soundtrack on such environments. The potential of sound both as a means to enhance the impact of the S3D visual information and to expand the S3D cinematic world beyond the boundaries of the visuals is large. This article reports on our research into the possibilities of using auditory depth cues within the soundtrack as a means of affecting the perception of depth within cinematic S3D scenes. We study two main distance-related auditory cues: high-end frequency loss and overall volume attenuation. A series of experiments explored the effectiveness of these auditory cues. Results, although not conclusive, indicate that the studied auditory cues can influence the audience judgement of depth in cinematic 3D scenes, sometimes in unexpected ways. We conclude that 3D filmmaking can benefit from further studies on the effectiveness of specific sound design techniques to enhance S3D cinema.

  2. Highly Omnidirectional and Frequency Controllable Carbon/Polyaniline-based 2D and 3D Monopole Antenna

    OpenAIRE

    Keun-Young Shin; Minkyu Kim; James S. Lee; Jyongsik Jang

    2015-01-01

    Highly omnidirectional and frequency controllable carbon/polyaniline (C/PANI)-based, two- (2D) and three-dimensional (3D) monopole antennas were fabricated using screen-printing and a one-step, dimensionally confined hydrothermal strategy, respectively. Solvated C/PANI was synthesized by low-temperature interfacial polymerization, during which strong π–π interactions between graphene and the quinoid rings of PANI resulted in an expanded PANI conformation with enhanced crystallinity and improv...

  3. Highly Omnidirectional and Frequency Controllable Carbon/Polyaniline-based 2D and 3D Monopole Antenna

    Science.gov (United States)

    Shin, Keun-Young; Kim, Minkyu; Lee, James S.; Jang, Jyongsik

    2015-09-01

    Highly omnidirectional and frequency controllable carbon/polyaniline (C/PANI)-based, two- (2D) and three-dimensional (3D) monopole antennas were fabricated using screen-printing and a one-step, dimensionally confined hydrothermal strategy, respectively. Solvated C/PANI was synthesized by low-temperature interfacial polymerization, during which strong π-π interactions between graphene and the quinoid rings of PANI resulted in an expanded PANI conformation with enhanced crystallinity and improved mechanical and electrical properties. Compared to antennas composed of pristine carbon or PANI-based 2D monopole structures, 2D monopole antennas composed of this enhanced hybrid material were highly efficient and amenable to high-frequency, omnidirectional electromagnetic waves. The mean frequency of C/PANI fiber-based 3D monopole antennas could be controlled by simply cutting and stretching the antenna. These antennas attained high peak gain (3.60 dBi), high directivity (3.91 dBi) and radiation efficiency (92.12%) relative to 2D monopole antenna. These improvements were attributed the high packing density and aspect ratios of C/PANI fibers and the removal of the flexible substrate. This approach offers a valuable and promising tool for producing highly omnidirectional and frequency-controllable, carbon-based monopole antennas for use in wireless networking communications on industrial, scientific, and medical (ISM) bands.

  4. Model based assessment of vestibular jawbone thickness using high frequency 3D ultrasound micro-scanning

    Science.gov (United States)

    Habor, Daniel; Neuhaus, Sarah; Vollborn, Thorsten; Wolfart, Stefan; Radermacher, Klaus; Heger, Stefan

    2013-03-01

    Endosseous implants are well-established in modern dentistry. However, without appropriate therapeutic intervention, progressive peri-implant bone loss may lead to failing implants. Conventionally, the particularly relevant vestibular jawbone thickness is monitored using radiographic 3D imaging methods. Ionizing radiation, as well as imaging artifacts caused by metallic implants and superstructures are major drawbacks of these imaging modalities. In this study, a high frequency ultrasound (HFUS) based approach to assess the vestibular jawbone thickness is being introduced. It should be emphasized that the presented method does not require ultrasound penetration of the jawbone. An in-vitro study using two porcine specimens with inserted endosseous implants has been carried out to assess the accuracy of our approach. The implant of the first specimen was equipped with a gingiva former while a polymer superstructure was mounted onto the implant of the second specimen. Ultrasound data has been acquired using a 4 degree of freedom (DOF) high frequency (vestibular peri-implant bone thickness has been assessed in the resulting 3D models. The accuracy of this approach has been evaluated by comparing the ultrasound based thickness measurement with a reference measurement acquired with an optical extra-oral 3D scanner prior to covering the specimens with gingiva. As a final result, the bone thicknesses of the two specimens were measured yielding an error of -46+/-89μm (first specimen) and 70+/-93μm (second specimen).

  5. Accuracy assessment of high frequency 3D ultrasound for digital impression-taking of prepared teeth

    Science.gov (United States)

    Heger, Stefan; Vollborn, Thorsten; Tinschert, Joachim; Wolfart, Stefan; Radermacher, Klaus

    2013-03-01

    Silicone based impression-taking of prepared teeth followed by plaster casting is well-established but potentially less reliable, error-prone and inefficient, particularly in combination with emerging techniques like computer aided design and manufacturing (CAD/CAM) of dental prosthesis. Intra-oral optical scanners for digital impression-taking have been introduced but until now some drawbacks still exist. Because optical waves can hardly penetrate liquids or soft-tissues, sub-gingival preparations still need to be uncovered invasively prior to scanning. High frequency ultrasound (HFUS) based micro-scanning has been recently investigated as an alternative to optical intra-oral scanning. Ultrasound is less sensitive against oral fluids and in principal able to penetrate gingiva without invasively exposing of sub-gingival preparations. Nevertheless, spatial resolution as well as digitization accuracy of an ultrasound based micro-scanning system remains a critical parameter because the ultrasound wavelength in water-like media such as gingiva is typically smaller than that of optical waves. In this contribution, the in-vitro accuracy of ultrasound based micro-scanning for tooth geometry reconstruction is being investigated and compared to its extra-oral optical counterpart. In order to increase the spatial resolution of the system, 2nd harmonic frequencies from a mechanically driven focused single element transducer were separated and corresponding 3D surface models were calculated for both fundamentals and 2nd harmonics. Measurements on phantoms, model teeth and human teeth were carried out for evaluation of spatial resolution and surface detection accuracy. Comparison of optical and ultrasound digital impression taking indicate that, in terms of accuracy, ultrasound based tooth digitization can be an alternative for optical impression-taking.

  6. Numerical Simulations of High-Frequency Respiratory Flows in 2D and 3D Lung Bifurcation Models

    Science.gov (United States)

    Chen, Zixi; Parameswaran, Shamini; Hu, Yingying; He, Zhaoming; Raj, Rishi; Parameswaran, Siva

    2014-07-01

    To better understand the human pulmonary system and optimize the high-frequency oscillatory ventilation (HFOV) design, numerical simulations were conducted under normal breathing frequency and HFOV condition using a CFD code Ansys Fluent and its user-defined C programs. 2D and 3D double bifurcating lung models were created, and the geometry corresponds to fifth to seventh generations of airways with the dimensions based on the Weibel's pulmonary model. Computations were carried out for different Reynolds numbers (Re = 400 and 1000) and Womersley numbers (α = 4 and 16) to study the air flow fields, gas transportation, and wall shear stresses in the lung airways. Flow structure was compared with experimental results. Both 2D and 3D numerical models successfully reproduced many results observed in the experiment. The oxygen concentration distribution in the lung model was investigated to analyze the influence of flow oscillation on gas transport inside the lung model.

  7. High-frequency 3D echodentographic imaging modality for early assessment of periodontal diseases: in vitro study

    Science.gov (United States)

    Mahmoud, Ahmed M.; Ngan, Peter; Crout, Richard; Mukdadi, Osama M.

    2009-02-01

    The use of ultrasound in dentistry is still an open growing area of research. Currently, there is a lack of imaging modalities to accurately predict minute structures and defects in the jawbone. In particular, the inability of 2D radiographic images to detect bony periodontal defects resulted from infection of the periodontium. This study investigates the feasibility of high frequency ultrasound to reconstruct high resolution 3D surface images of human jawbone. Methods: A dentate and non-dentate mandibles were used in this study. The system employs high frequency single-element ultrasound focused transducers (15-30 MHz) for scanning. Continuous acquisition using a 1 GHz data acquisition card is synchronized with a high precision two-dimensional stage positioning system of +/-1 μm resolution for acquiring accurate and quantitative measurements of the mandible in vitro. Radio frequency (RF) signals are acquired laterally 44-45.5 μm apart for each frame. Different frames are reconstructed 500 μm apart for the 3D reconstruction. Signal processing algorithms are applied on the received ultrasound signals for filtering, focusing, and envelope detection before frame reconstruction. Furthermore, an edge detection technique is adopted to detect the bone surface in each frame. Finally, all edges are combined together in order to render a 3D surface image of the jawbone. Major anatomical landmarks on the resultant images were confirmed with the anatomical structures on the mandibles to show the efficacy of the system. Comparison were also made with conventional 2D radiographs to show the superiority of the ultrasound imaging system in diagnosing small defects in the lateral, axial and elevation planes of space. Results: The landmarks on all ultrasound images matched with those on the mandible, indicating the efficacy of the system in detecting small structures in human jaw bones. Comparison with conventional 2D radiographic images of the same mandible showed superiority of

  8. High-Resolution Detection of Five Frequencies in a Single 3D Spectrum: HNHCACO - a Bidirectional Coherence Transfer Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Pang Yuxi; Zeng Lei; Kurochkin, Alexander V.; Zuiderweg, Erik R.P. [University of Michigan, Biophysics Research Division (United States)

    1998-02-15

    A new triple-resonance pulse sequence, 3D HNHCACO, is introduced and discussed, which identifies sequential correlations of the backbone nuclei (H{alpha}(i-1), C{alpha}(i-1), C'(i-1), NH(i)) of doubly labeled proteins in H2O. The three-dimensional (3D) method utilizes a recording of 15N and 13C resonances in a single indirect time domain, the 13C' resonance in another indirect time domain, and detects both NH and H{alpha} protons. A bidirectional coherence transfer (NH(i) {r_reversible} N(i) {r_reversible} C'(i-1) {r_reversible} C{alpha}(i-1) {r_reversible} H{alpha}(i-1)) is effectuated, resulting in a single high-resolution 3D spectrum that contains the frequencies of all five backbone nuclei. The experiment was applied to the 12.3 kDa ribonuclease from Bacillus intermedius (Binase)

  9. Utilization of multiple frequencies in 3D nonlinear microwave imaging

    DEFF Research Database (Denmark)

    Jensen, Peter Damsgaard; Rubæk, Tonny; Mohr, Johan Jacob

    2012-01-01

    The use of multiple frequencies in a nonlinear microwave algorithm is considered. Using multiple frequencies allows for obtaining the improved resolution available at the higher frequencies while retaining the regularizing effects of the lower frequencies. However, a number of different challenges...... at lower frequencies are used as starting guesses for reconstructions at higher frequencies. The performance is illustrated using simulated 2-D data and data obtained with the 3-D DTU microwave imaging system....

  10. A high capacity 3D steganography algorithm.

    Science.gov (United States)

    Chao, Min-Wen; Lin, Chao-hung; Yu, Cheng-Wei; Lee, Tong-Yee

    2009-01-01

    In this paper, we present a very high-capacity and low-distortion 3D steganography scheme. Our steganography approach is based on a novel multilayered embedding scheme to hide secret messages in the vertices of 3D polygon models. Experimental results show that the cover model distortion is very small as the number of hiding layers ranges from 7 to 13 layers. To the best of our knowledge, this novel approach can provide much higher hiding capacity than other state-of-the-art approaches, while obeying the low distortion and security basic requirements for steganography on 3D models.

  11. Low frequency electromagnetic wave propagation in 3D plasma configurations

    OpenAIRE

    Popovitch, Pavel

    2004-01-01

    We investigate low-frequency electromagnetic wave propagation and absorption properties in 2D and 3D plasma configurations. For these purposes, we have developed a new full-wave 3D code LEMan that determines a global solution of the wave equation in bounded stellarator plasmas excited with an external antenna. No assumption on the wavelength compared to the plasma size is made, all the effects of the 3D geometry and finite plasma extent are included. The equation is formulated in terms of ele...

  12. High accuracy 3-D laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    We have developed a mono-static staring 3-D laser radar based on gated viewing with range accuracy below 1 m at 10 m and 1 cm at 100. We use a high sensitivity, fast, intensified CCD camera, and a Nd:Yag passively Q-switched 32.4 kHz pulsed green laser at 532 nm. The CCD has 752x582 pixels. Camera...... shutter is controlled in steps of 100 ps. Camera delay is controlled in steps of 100 ps. Each laser pulse triggers the camera delay and shutter. A 3-D image is constructed from a sequence of 50-100 2-D reflectivity images, where each frame integrates about 700 laser pulses on the CCD. In 50 Hz video mode...... we record a 2-D sequence in a second and process a 3-D image in few seconds. We compare 3-D images with a system performance model....

  13. 3-D Printed High Power Microwave Magnetrons

    Science.gov (United States)

    Jordan, Nicholas; Greening, Geoffrey; Exelby, Steven; Gilgenbach, Ronald; Lau, Y. Y.; Hoff, Brad

    2015-11-01

    The size, weight, and power requirements of HPM systems are critical constraints on their viability, and can potentially be improved through the use of additive manufacturing techniques, which are rapidly increasing in capability and affordability. Recent experiments on the UM Recirculating Planar Magnetron (RPM), have explored the use of 3-D printed components in a HPM system. The system was driven by MELBA-C, a Marx-Abramyan system which delivers a -300 kV voltage pulse for 0.3-1.0 us, with a 0.15-0.3 T axial magnetic field applied by a pair of electromagnets. Anode blocks were printed from Water Shed XC 11122 photopolymer using a stereolithography process, and prepared with either a spray-coated or electroplated finish. Both manufacturing processes were compared against baseline data for a machined aluminum anode, noting any differences in power output, oscillation frequency, and mode stability. Evolution and durability of the 3-D printed structures were noted both visually and by tracking vacuum inventories via a residual gas analyzer. Research supported by AFOSR (grant #FA9550-15-1-0097) and AFRL.

  14. High resolution 3D nonlinear integrated inversion

    Institute of Scientific and Technical Information of China (English)

    Li Yong; Wang Xuben; Li Zhirong; Li Qiong; Li Zhengwen

    2009-01-01

    The high resolution 3D nonlinear integrated inversion method is based on nonlinear theory. Under layer control, the log data from several wells (or all wells) in the study area and seismic trace data adjacent to the wells are input to a network with multiple inputs and outputs and are integratedly trained to obtain an adaptive weight function of the entire study area. Integrated nonlinear mapping relationships are built and updated by the lateral and vertical geologic variations of the reservoirs. Therefore, the inversion process and its inversion results can be constrained and controlled and a stable seismic inversion section with high resolution with velocity inversion, impedance inversion, and density inversion sections, can be gained. Good geologic effects have been obtained in model computation tests and real data processing, which verified that this method has high precision, good practicality, and can be used for quantitative reservoir analysis.

  15. MAP3D: a media processor approach for high-end 3D graphics

    Science.gov (United States)

    Darsa, Lucia; Stadnicki, Steven; Basoglu, Chris

    1999-12-01

    Equator Technologies, Inc. has used a software-first approach to produce several programmable and advanced VLIW processor architectures that have the flexibility to run both traditional systems tasks and an array of media-rich applications. For example, Equator's MAP1000A is the world's fastest single-chip programmable signal and image processor targeted for digital consumer and office automation markets. The Equator MAP3D is a proposal for the architecture of the next generation of the Equator MAP family. The MAP3D is designed to achieve high-end 3D performance and a variety of customizable special effects by combining special graphics features with high performance floating-point and media processor architecture. As a programmable media processor, it offers the advantages of a completely configurable 3D pipeline--allowing developers to experiment with different algorithms and to tailor their pipeline to achieve the highest performance for a particular application. With the support of Equator's advanced C compiler and toolkit, MAP3D programs can be written in a high-level language. This allows the compiler to successfully find and exploit any parallelism in a programmer's code, thus decreasing the time to market of a given applications. The ability to run an operating system makes it possible to run concurrent applications in the MAP3D chip, such as video decoding while executing the 3D pipelines, so that integration of applications is easily achieved--using real-time decoded imagery for texturing 3D objects, for instance. This novel architecture enables an affordable, integrated solution for high performance 3D graphics.

  16. Fast 3D subsurface imaging with stepped-frequency GPR

    Science.gov (United States)

    Masarik, Matthew P.; Burns, Joseph; Thelen, Brian T.; Sutter, Lena

    2015-05-01

    This paper investigates an algorithm for forming 3D images of the subsurface using stepped-frequency GPR data. The algorithm is specifically designed for a handheld GPR and therefore accounts for the irregular sampling pattern in the data and the spatially-variant air-ground interface by estimating an effective "ground-plane" and then registering the data to the plane. The algorithm efficiently solves the 4th-order polynomial for the Snell reflection points using a fully vectorized iterative scheme. The forward operator is implemented efficiently using an accelerated nonuniform FFT (Greengard and Lee, 2004); the adjoint operator is implemented efficiently using an interpolation step coupled with an upsampled FFT. The imaging is done as a linearized version of the full inverse problem, which is regularized using a sparsity constraint to reduce sidelobes and therefore improve image localization. Applying an appropriate sparsity constraint, the algorithm is able to eliminate most the surrounding clutter and sidelobes, while still rendering valuable image properties such as shape and size. The algorithm is applied to simulated data, controlled experimental data (made available by Dr. Waymond Scott, Georgia Institute of Technology), and government-provided data with irregular sampling and air-ground interface.

  17. High-speed 3D shape measurement using array projection

    Science.gov (United States)

    Heist, Stefan; Sieler, Marcel; Breitbarth, Andreas; Kühmstedt, Peter; Notni, Gunther

    2013-04-01

    Measuring the three-dimensional (3D) surface shape of objects in real time has become an important task e.g. in industrial quality management or medical sciences. Stereo vision-based arrangements in connection with pattern projection offer high data acquisition speed and low computation time. However, these coded-light techniques are limited by the projection speed which is conventionally in the range of 200. . .250Hz. In this contribution, we present the concepts and a realized setup of a so-called 3D array projector. It is ultra-slim, but nonetheless able to project fixed patterns with high brightness and depth of focus. Furthermore, frame rates up to the 100 kHz range are achievable without any need of mechanically moving parts since the projection speed is limited mainly by the switching frequency of the used LEDs. According to the measurement requirements, type and structure of the patterns can be chosen almost freely: linear or sinusoidal fringes, binary codes such as the Gray code, square, hexagonal or random patterns and many more. First investigations on the functionality of such a 3D array projector were conducted using a prototype with a combination of Gray codes and phase-shifted sinusoidal fringes. Our contribution proves the high brightness of the proposed projector, its sharpness and the good Michelson contrast of the fringe patterns. We deal with the patterns' homogeneity and the accuracy of the phase shift between the sinusoidal patterns. Furthermore, we present first measurement results and outline future research which is, inter alia, addressed to the use of other structured light techniques with the help of new purpose-built 3D array projector prototypes.

  18. Reconstruction of High Resolution 3D Objects from Incomplete Images and 3D Information

    Directory of Open Access Journals (Sweden)

    Alexander Pacheco

    2014-05-01

    Full Text Available To this day, digital object reconstruction is a quite complex area that requires many techniques and novel approaches, in which high-resolution 3D objects present one of the biggest challenges. There are mainly two different methods that can be used to reconstruct high resolution objects and images: passive methods and active methods. This methods depend on the type of information available as input for modeling 3D objects. The passive methods use information contained in the images and the active methods make use of controlled light sources, such as lasers. The reconstruction of 3D objects is quite complex and there is no unique solution- The use of specific methodologies for the reconstruction of certain objects it’s also very common, such as human faces, molecular structures, etc. This paper proposes a novel hybrid methodology, composed by 10 phases that combine active and passive methods, using images and a laser in order to supplement the missing information and obtain better results in the 3D object reconstruction. Finally, the proposed methodology proved its efficiency in two complex topological complex objects.

  19. A 3D-printed high power nuclear spin polarizer.

    Science.gov (United States)

    Nikolaou, Panayiotis; Coffey, Aaron M; Walkup, Laura L; Gust, Brogan M; LaPierre, Cristen D; Koehnemann, Edward; Barlow, Michael J; Rosen, Matthew S; Goodson, Boyd M; Chekmenev, Eduard Y

    2014-01-29

    Three-dimensional printing with high-temperature plastic is used to enable spin exchange optical pumping (SEOP) and hyperpolarization of xenon-129 gas. The use of 3D printed structures increases the simplicity of integration of the following key components with a variable temperature SEOP probe: (i) in situ NMR circuit operating at 84 kHz (Larmor frequencies of (129)Xe and (1)H nuclear spins), (ii) 3D printing dramatically reduces production time and expenses while allowing reproducibility and integration of "off-the-shelf" components and enables the concept of printing on demand. The utility of this SEOP setup is demonstrated here to obtain near-unity (129)Xe polarization values in a 0.5 L optical pumping cell, including ∼74 ± 7% at 1000 Torr xenon partial pressure, a record value at such high Xe density. Values for the (129)Xe polarization exponential build-up rate [(3.63 ± 0.15) × 10(-2) min(-1)] and in-cell (129)Xe spin-lattice relaxation time (T1 = 2.19 ± 0.06 h) for 1000 Torr Xe were in excellent agreement with the ratio of the gas-phase polarizations for (129)Xe and Rb (PRb ∼ 96%). Hyperpolarization-enhanced (129)Xe gas imaging was demonstrated with a spherical phantom following automated gas transfer from the polarizer. Taken together, these results support the development of a wide range of chemical, biochemical, material science, and biomedical applications.

  20. Highly compressible 3D periodic graphene aerogel microlattices.

    Science.gov (United States)

    Zhu, Cheng; Han, T Yong-Jin; Duoss, Eric B; Golobic, Alexandra M; Kuntz, Joshua D; Spadaccini, Christopher M; Worsley, Marcus A

    2015-04-22

    Graphene is a two-dimensional material that offers a unique combination of low density, exceptional mechanical properties, large surface area and excellent electrical conductivity. Recent progress has produced bulk 3D assemblies of graphene, such as graphene aerogels, but they possess purely stochastic porous networks, which limit their performance compared with the potential of an engineered architecture. Here we report the fabrication of periodic graphene aerogel microlattices, possessing an engineered architecture via a 3D printing technique known as direct ink writing. The 3D printed graphene aerogels are lightweight, highly conductive and exhibit supercompressibility (up to 90% compressive strain). Moreover, the Young's moduli of the 3D printed graphene aerogels show an order of magnitude improvement over bulk graphene materials with comparable geometric density and possess large surface areas. Adapting the 3D printing technique to graphene aerogels realizes the possibility of fabricating a myriad of complex aerogel architectures for a broad range of applications.

  1. Highly compressible 3D periodic graphene aerogel microlattices

    Science.gov (United States)

    Zhu, Cheng; Han, T. Yong-Jin; Duoss, Eric B.; Golobic, Alexandra M.; Kuntz, Joshua D.; Spadaccini, Christopher M.; Worsley, Marcus A.

    2015-01-01

    Graphene is a two-dimensional material that offers a unique combination of low density, exceptional mechanical properties, large surface area and excellent electrical conductivity. Recent progress has produced bulk 3D assemblies of graphene, such as graphene aerogels, but they possess purely stochastic porous networks, which limit their performance compared with the potential of an engineered architecture. Here we report the fabrication of periodic graphene aerogel microlattices, possessing an engineered architecture via a 3D printing technique known as direct ink writing. The 3D printed graphene aerogels are lightweight, highly conductive and exhibit supercompressibility (up to 90% compressive strain). Moreover, the Young's moduli of the 3D printed graphene aerogels show an order of magnitude improvement over bulk graphene materials with comparable geometric density and possess large surface areas. Adapting the 3D printing technique to graphene aerogels realizes the possibility of fabricating a myriad of complex aerogel architectures for a broad range of applications. PMID:25902277

  2. A new method using orthogonal two-frequency grating in online 3D measurement

    Science.gov (United States)

    Peng, Kuang; Cao, Yiping; Wu, Yingchun; Lu, Mingteng

    2016-09-01

    In online 3D measurement, a new method using orthogonal two-frequency grating based on Phase Measuring Profilometry(PMP) is proposed. The modulation of the entire measured object is used to match pixels and this proposed method successfully resolves the contradiction of the demand for different frequency fringes between the extraction of the modulation information and the phase unwrapping. The high-frequency fringe is used to catch the better modulation patterns for pixel matching, and the low-frequency fringe is used to calculate the phase distribution and avoid phase unwrapping error. In addition, to extract the better modulation patterns for pixel matching, the flat filtering window replaces the circular filtering window to avoid the spectrum aliasing phenomenon. The simulations and experiments show its feasibility.

  3. Efficient 2D and 3D multiparameters frequency-domain full waveform inversion (Invited)

    Science.gov (United States)

    Virieux, J.; Operto, S.; Ribodetti, A.; Ben Hadj Ali, H.; Brossier, R.; Etienne, V.; Gholami, Y.; Hu, G.; Jia, Y.; Pageot, D.; Prieux, V.

    2010-12-01

    With the tremendous increase of the computational power provided by large-scale distributed-memory platforms and the development of dense 3D multi-component wide-aperture/wide-azimuth surveys, full waveform inversion (FWI) introduced in geophysics by Albert Tarantola has become a re-emerging technique to build high-resolution velocity models of the subsurface. Because of the cost of the forward modeling and the high dimensionality of the model space, full waveform inversion is actually a local optimization problem, the aim of which is the minimization of the misfit between the recorded and modeled seismic wavefields. Among all possible minimization criteria, the L1 norm provides the most robust and easy-to-tune criterion. With such criterion, white noise in all seismograms with outliers does not prevent the convergence to the nearly same minimum as for noise-free data. The frequency formulation of the FWI allows coarse sampling of the frequencies data over few frequencies for the reconstruction of the medium when wide-aperture geometries are considered. A preconditioned quasi-Newton L-BFGS modified algorithm provides scaled gradients of the misfit function for each class of parameters. The gradient is computed by the adjoint-state method where the forward field is stored in the core memory of the computer while computing the backpropagation of residuals for cross-correlation at each point of the medium, thanks to the frequency-domain approach. We are using a sequential multiscale hierarchical inversion algorithm with two nested levels of data preconditioning with respect to frequency and first-arrival time. We are able to reconstruct both Vp and Vs velocity structures in various offshore and onshore environments various configurations of crustal investigation where both body waves (and surface) waves are progressively included in the inversion scheme. Solving the forward problem for 2D geometry could be efficiently performed in frequency by using a direct solver

  4. High Resolution 3D Radar Imaging of Comet Interiors

    Science.gov (United States)

    Asphaug, E. I.; Gim, Y.; Belton, M.; Brophy, J.; Weissman, P. R.; Heggy, E.

    2012-12-01

    Knowing the interiors of comets and other primitive bodies is fundamental to our understanding of how planets formed. We have developed a Discovery-class mission formulation, Comet Radar Explorer (CORE), based on the use of previously flown planetary radar sounding techniques, with the goal of obtaining high resolution 3D images of the interior of a small primitive body. We focus on the Jupiter-Family Comets (JFCs) as these are among the most primitive bodies reachable by spacecraft. Scattered in from far beyond Neptune, they are ultimate targets of a cryogenic sample return mission according to the Decadal Survey. Other suitable targets include primitive NEOs, Main Belt Comets, and Jupiter Trojans. The approach is optimal for small icy bodies ~3-20 km diameter with spin periods faster than about 12 hours, since (a) navigation is relatively easy, (b) radar penetration is global for decameter wavelengths, and (c) repeated overlapping ground tracks are obtained. The science mission can be as short as ~1 month for a fast-rotating JFC. Bodies smaller than ~1 km can be globally imaged, but the navigation solutions are less accurate and the relative resolution is coarse. Larger comets are more interesting, but radar signal is unlikely to be reflected from depths greater than ~10 km. So, JFCs are excellent targets for a variety of reasons. We furthermore focus on the use of Solar Electric Propulsion (SEP) to rendezvous shortly after the comet's perihelion. This approach leaves us with ample power for science operations under dormant conditions beyond ~2-3 AU. This leads to a natural mission approach of distant observation, followed by closer inspection, terminated by a dedicated radar mapping orbit. Radar reflections are obtained from a polar orbit about the icy nucleus, which spins underneath. Echoes are obtained from a sounder operating at dual frequencies 5 and 15 MHz, with 1 and 10 MHz bandwidths respectively. The dense network of echoes is used to obtain global 3D

  5. Highly-stretchable 3D-architected Mechanical Metamaterials

    Science.gov (United States)

    Jiang, Yanhui; Wang, Qiming

    2016-09-01

    Soft materials featuring both 3D free-form architectures and high stretchability are highly desirable for a number of engineering applications ranging from cushion modulators, soft robots to stretchable electronics; however, both the manufacturing and fundamental mechanics are largely elusive. Here, we overcome the manufacturing difficulties and report a class of mechanical metamaterials that not only features 3D free-form lattice architectures but also poses ultrahigh reversible stretchability (strain > 414%), 4 times higher than that of the existing counterparts with the similar complexity of 3D architectures. The microarchitected metamaterials, made of highly stretchable elastomers, are realized through an additive manufacturing technique, projection microstereolithography, and its postprocessing. With the fabricated metamaterials, we reveal their exotic mechanical behaviors: Under large-strain tension, their moduli follow a linear scaling relationship with their densities regardless of architecture types, in sharp contrast to the architecture-dependent modulus power-law of the existing engineering materials; under large-strain compression, they present tunable negative-stiffness that enables ultrahigh energy absorption efficiencies. To harness their extraordinary stretchability and microstructures, we demonstrate that the metamaterials open a number of application avenues in lightweight and flexible structure connectors, ultraefficient dampers, 3D meshed rehabilitation structures and stretchable electronics with designed 3D anisotropic conductivity.

  6. High density 3D printed microfluidic valves, pumps, and multiplexers.

    Science.gov (United States)

    Gong, Hua; Woolley, Adam T; Nordin, Gregory P

    2016-07-01

    In this paper we demonstrate that 3D printing with a digital light processor stereolithographic (DLP-SLA) 3D printer can be used to create high density microfluidic devices with active components such as valves and pumps. Leveraging our previous work on optical formulation of inexpensive resins (RSC Adv., 2015, 5, 106621), we demonstrate valves with only 10% of the volume of our original 3D printed valves (Biomicrofluidics, 2015, 9, 016501), which were already the smallest that have been reported. Moreover, we show that incorporation of a thermal initiator in the resin formulation along with a post-print bake can dramatically improve the durability of 3D printed valves up to 1 million actuations. Using two valves and a valve-like displacement chamber (DC), we also create compact 3D printed pumps. With 5-phase actuation and a 15 ms phase interval, we obtain pump flow rates as high as 40 μL min(-1). We also characterize maximum pump back pressure (i.e., maximum pressure the pump can work against), maximum flow rate (flow rate when there is zero back pressure), and flow rate as a function of the height of the pump outlet. We further demonstrate combining 5 valves and one DC to create a 3-to-2 multiplexer with integrated pump. In addition to serial multiplexing, we also show that the device can operate as a mixer. Importantly, we illustrate the rapid fabrication and test cycles that 3D printing makes possible by implementing a new multiplexer design to improve mixing, and fabricate and test it within one day. PMID:27242064

  7. High density 3D printed microfluidic valves, pumps, and multiplexers.

    Science.gov (United States)

    Gong, Hua; Woolley, Adam T; Nordin, Gregory P

    2016-07-01

    In this paper we demonstrate that 3D printing with a digital light processor stereolithographic (DLP-SLA) 3D printer can be used to create high density microfluidic devices with active components such as valves and pumps. Leveraging our previous work on optical formulation of inexpensive resins (RSC Adv., 2015, 5, 106621), we demonstrate valves with only 10% of the volume of our original 3D printed valves (Biomicrofluidics, 2015, 9, 016501), which were already the smallest that have been reported. Moreover, we show that incorporation of a thermal initiator in the resin formulation along with a post-print bake can dramatically improve the durability of 3D printed valves up to 1 million actuations. Using two valves and a valve-like displacement chamber (DC), we also create compact 3D printed pumps. With 5-phase actuation and a 15 ms phase interval, we obtain pump flow rates as high as 40 μL min(-1). We also characterize maximum pump back pressure (i.e., maximum pressure the pump can work against), maximum flow rate (flow rate when there is zero back pressure), and flow rate as a function of the height of the pump outlet. We further demonstrate combining 5 valves and one DC to create a 3-to-2 multiplexer with integrated pump. In addition to serial multiplexing, we also show that the device can operate as a mixer. Importantly, we illustrate the rapid fabrication and test cycles that 3D printing makes possible by implementing a new multiplexer design to improve mixing, and fabricate and test it within one day.

  8. CVD Diamond Sink Application in High Power 3D MCMs

    Institute of Scientific and Technical Information of China (English)

    XIE Kuo-jun; JIANG Chang-shun; LI Cheng-yue

    2005-01-01

    As electronic packages become more compact, run at faster speeds and dissipate more heat, package designers need more effective thermal management materials. CVD diamond, because of its high thermal conductivity, low dielectric loss and its great mechanical strength, is an excellent material for three dimensional (3D) multichip modules (MCMs) in the next generation compact high speed computers and high power microwave components. In this paper, we have synthesized a large area freestanding diamond films and substrates, and polished diamond substrates, which make MCMs diamond film sink becomes a reality.

  9. 3-D MAPPING TECHNOLOGIES FOR HIGH LEVEL WASTE TANKS

    Energy Technology Data Exchange (ETDEWEB)

    Marzolf, A.; Folsom, M.

    2010-08-31

    time-of-flight data (3D image) collected with a single laser pulse, high frame rates, direct calculation of range, blur-free images without motion distortion, no need for precision scanning mechanisms, ability to combine 3D flash LIDAR with 2D cameras for 2D texture over 3D depth, and no moving parts. The major disadvantage of the 3D flash LIDAR camera is the cost of approximately $150,000, not including the software development time and repackaging of the camera for deployment in the waste tanks.

  10. High-Q 3D coaxial resonators for cavity QED

    Science.gov (United States)

    Yoon, Taekwan; Owens, John C.; Naik, Ravi; Lachapelle, Aman; Ma, Ruichao; Simon, Jonathan; Schuster, David I.

    Three-dimensional microwave resonators provide an alternative approach to transmission-line resonators used in most current circuit QED experiments. Their large mode volume greatly reduces the surface dielectric losses that limits the coherence of superconducting circuits, and the well-isolated and controlled cavity modes further suppress coupling to the environment. In this work, we focus on unibody 3D coaxial cavities which are only evanescently coupled and free from losses due to metal-metal interfaces, allowing us to reach extremely high quality-factors. We achieve quality-factor of up to 170 million using 4N6 Aluminum at superconducting temperatures, corresponding to an energy ringdown time of ~4ms. We extend our methods to other materials including Niobium, NbTi, and copper coated with Tin-Lead solder. These cavities can be further explored to study their properties under magnetic field or upon coupling to superconducting Josephson junction qubits, e.g. 3D transmon qubits. Such 3D cavity QED system can be used for quantum information applications, or quantum simulation in coupled cavity arrays.

  11. Design of the 1.5 MW, 30-96 MHz ultra-wideband 3 dB high power hybrid coupler for Ion Cyclotron Resonance Frequency (ICRF) heating in fusion grade reactor

    Energy Technology Data Exchange (ETDEWEB)

    Yadav, Rana Pratap, E-mail: ranayadav97@gmail.com; Kumar, Sunil; Kulkarni, S. V. [Thapar University, Patiala, Punjab 147004, India and Institute for Plasma Research, Gandhinagar 382428 (India)

    2016-01-15

    Design and developmental procedure of strip-line based 1.5 MW, 30-96 MHz, ultra-wideband high power 3 dB hybrid coupler has been presented and its applicability in ion cyclotron resonance heating (ICRH) in tokamak is discussed. For the high power handling capability, spacing between conductors and ground need to very high. Hence other structural parameters like strip-width, strip thickness coupling gap, and junction also become large which can be gone upto optimum limit where various constrains like fabrication tolerance, discontinuities, and excitation of higher TE and TM modes become prominent and significantly deteriorates the desired parameters of the coupled lines system. In designed hybrid coupler, two 8.34 dB coupled lines are connected in tandem to get desired coupling of 3 dB and air is used as dielectric. The spacing between ground and conductors are taken as 0.164 m for 1.5 MW power handling capability. To have the desired spacing, each of 8.34 dB segments are designed with inner dimension of 3.6 × 1.0 × 40 cm where constraints have been significantly realized, compensated, and applied in designing of 1.5 MW hybrid coupler and presented in paper.

  12. Design of the 1.5 MW, 30-96 MHz ultra-wideband 3 dB high power hybrid coupler for Ion Cyclotron Resonance Frequency (ICRF) heating in fusion grade reactor

    Science.gov (United States)

    Yadav, Rana Pratap; Kumar, Sunil; Kulkarni, S. V.

    2016-01-01

    Design and developmental procedure of strip-line based 1.5 MW, 30-96 MHz, ultra-wideband high power 3 dB hybrid coupler has been presented and its applicability in ion cyclotron resonance heating (ICRH) in tokamak is discussed. For the high power handling capability, spacing between conductors and ground need to very high. Hence other structural parameters like strip-width, strip thickness coupling gap, and junction also become large which can be gone upto optimum limit where various constrains like fabrication tolerance, discontinuities, and excitation of higher TE and TM modes become prominent and significantly deteriorates the desired parameters of the coupled lines system. In designed hybrid coupler, two 8.34 dB coupled lines are connected in tandem to get desired coupling of 3 dB and air is used as dielectric. The spacing between ground and conductors are taken as 0.164 m for 1.5 MW power handling capability. To have the desired spacing, each of 8.34 dB segments are designed with inner dimension of 3.6 × 1.0 × 40 cm where constraints have been significantly realized, compensated, and applied in designing of 1.5 MW hybrid coupler and presented in paper.

  13. Design of the 1.5 MW, 30-96 MHz ultra-wideband 3 dB high power hybrid coupler for Ion Cyclotron Resonance Frequency (ICRF) heating in fusion grade reactor

    International Nuclear Information System (INIS)

    Design and developmental procedure of strip-line based 1.5 MW, 30-96 MHz, ultra-wideband high power 3 dB hybrid coupler has been presented and its applicability in ion cyclotron resonance heating (ICRH) in tokamak is discussed. For the high power handling capability, spacing between conductors and ground need to very high. Hence other structural parameters like strip-width, strip thickness coupling gap, and junction also become large which can be gone upto optimum limit where various constrains like fabrication tolerance, discontinuities, and excitation of higher TE and TM modes become prominent and significantly deteriorates the desired parameters of the coupled lines system. In designed hybrid coupler, two 8.34 dB coupled lines are connected in tandem to get desired coupling of 3 dB and air is used as dielectric. The spacing between ground and conductors are taken as 0.164 m for 1.5 MW power handling capability. To have the desired spacing, each of 8.34 dB segments are designed with inner dimension of 3.6 × 1.0 × 40 cm where constraints have been significantly realized, compensated, and applied in designing of 1.5 MW hybrid coupler and presented in paper

  14. Emulsion Inks for 3D Printing of High Porosity Materials.

    Science.gov (United States)

    Sears, Nicholas A; Dhavalikar, Prachi S; Cosgriff-Hernandez, Elizabeth M

    2016-08-01

    Photocurable emulsion inks for use with solid freeform fabrication (SFF) to generate constructs with hierarchical porosity are presented. A high internal phase emulsion (HIPE) templating technique was utilized to prepare water-in-oil emulsions from a hydrophobic photopolymer, surfactant, and water. These HIPEs displayed strong shear thinning behavior that permitted layer-by-layer deposition into complex shapes and adequately high viscosity at low shear for shape retention after extrusion. Each layer was actively polymerized with an ultraviolet cure-on-dispense (CoD) technique and compositions with sufficient viscosity were able to produce tall, complex scaffolds with an internal lattice structure and microscale porosity. Evaluation of the rheological and cure properties indicated that the viscosity and cure rate both played an important role in print fidelity. These 3D printed polyHIPE constructs benefit from the tunable pore structure of emulsion templated material and the designed architecture of 3D printing. As such, these emulsion inks can be used to create ultra high porosity constructs with complex geometries and internal lattice structures not possible with traditional manufacturing techniques. PMID:27305061

  15. Emulsion Inks for 3D Printing of High Porosity Materials.

    Science.gov (United States)

    Sears, Nicholas A; Dhavalikar, Prachi S; Cosgriff-Hernandez, Elizabeth M

    2016-08-01

    Photocurable emulsion inks for use with solid freeform fabrication (SFF) to generate constructs with hierarchical porosity are presented. A high internal phase emulsion (HIPE) templating technique was utilized to prepare water-in-oil emulsions from a hydrophobic photopolymer, surfactant, and water. These HIPEs displayed strong shear thinning behavior that permitted layer-by-layer deposition into complex shapes and adequately high viscosity at low shear for shape retention after extrusion. Each layer was actively polymerized with an ultraviolet cure-on-dispense (CoD) technique and compositions with sufficient viscosity were able to produce tall, complex scaffolds with an internal lattice structure and microscale porosity. Evaluation of the rheological and cure properties indicated that the viscosity and cure rate both played an important role in print fidelity. These 3D printed polyHIPE constructs benefit from the tunable pore structure of emulsion templated material and the designed architecture of 3D printing. As such, these emulsion inks can be used to create ultra high porosity constructs with complex geometries and internal lattice structures not possible with traditional manufacturing techniques.

  16. High Current Density 2D/3D Esaki Tunnel Diodes

    CERN Document Server

    Krishnamoorthy, Sriram; Lee, Choong Hee; Zhang, Yuewei; McCulloch, William D; Johnson, Jared M; Hwang, Jinwoo; Wu, Yiying; Rajan, Siddharth

    2016-01-01

    The integration of two-dimensional materials such as transition metal dichalcogenides with bulk semiconductors offer interesting opportunities for 2D/3D heterojunction-based novel device structures without any constraints of lattice matching. By exploiting the favorable band alignment at the GaN/MoS2 heterojunction, an Esaki interband tunnel diode is demonstrated by transferring large area, Nb-doped, p-type MoS2 onto heavily n-doped GaN. A peak current density of 446 A/cm2 with repeatable room temperature negative differential resistance, peak to valley current ratio of 1.2, and minimal hysteresis was measured in the MoS2/GaN non-epitaxial tunnel diode. A high current density of 1 kA/cm2 was measured in the Zener mode (reverse bias) at -1 V bias. The GaN/MoS2 tunnel junction was also modeled by treating MoS2 as a bulk semiconductor, and the electrostatics at the 2D/3D interface was found to be crucial in explaining the experimentally observed device characteristics.

  17. The novel high-performance 3-D MT inverse solver

    Science.gov (United States)

    Kruglyakov, Mikhail; Geraskin, Alexey; Kuvshinov, Alexey

    2016-04-01

    We present novel, robust, scalable, and fast 3-D magnetotelluric (MT) inverse solver. The solver is written in multi-language paradigm to make it as efficient, readable and maintainable as possible. Separation of concerns and single responsibility concepts go through implementation of the solver. As a forward modelling engine a modern scalable solver extrEMe, based on contracting integral equation approach, is used. Iterative gradient-type (quasi-Newton) optimization scheme is invoked to search for (regularized) inverse problem solution, and adjoint source approach is used to calculate efficiently the gradient of the misfit. The inverse solver is able to deal with highly detailed and contrasting models, allows for working (separately or jointly) with any type of MT responses, and supports massive parallelization. Moreover, different parallelization strategies implemented in the code allow optimal usage of available computational resources for a given problem statement. To parameterize an inverse domain the so-called mask parameterization is implemented, which means that one can merge any subset of forward modelling cells in order to account for (usually) irregular distribution of observation sites. We report results of 3-D numerical experiments aimed at analysing the robustness, performance and scalability of the code. In particular, our computational experiments carried out at different platforms ranging from modern laptops to HPC Piz Daint (6th supercomputer in the world) demonstrate practically linear scalability of the code up to thousands of nodes.

  18. AUTOMATED, HIGHLY ACCURATE VERIFICATION OF RELAP5-3D

    Energy Technology Data Exchange (ETDEWEB)

    George L Mesina; David Aumiller; Francis Buschman

    2014-07-01

    Computer programs that analyze light water reactor safety solve complex systems of governing, closure and special process equations to model the underlying physics. In addition, these programs incorporate many other features and are quite large. RELAP5-3D[1] has over 300,000 lines of coding for physics, input, output, data management, user-interaction, and post-processing. For software quality assurance, the code must be verified and validated before being released to users. Verification ensures that a program is built right by checking that it meets its design specifications. Recently, there has been an increased importance on the development of automated verification processes that compare coding against its documented algorithms and equations and compares its calculations against analytical solutions and the method of manufactured solutions[2]. For the first time, the ability exists to ensure that the data transfer operations associated with timestep advancement/repeating and writing/reading a solution to a file have no unintended consequences. To ensure that the code performs as intended over its extensive list of applications, an automated and highly accurate verification method has been modified and applied to RELAP5-3D. Furthermore, mathematical analysis of the adequacy of the checks used in the comparisons is provided.

  19. (abstract) A High Throughput 3-D Inner Product Processor

    Science.gov (United States)

    Daud, Tuan

    1996-01-01

    A particularily challenging image processing application is the real time scene acquisition and object discrimination. It requires spatio-temporal recognition of point and resolved objects at high speeds with parallel processing algorithms. Neural network paradigms provide fine grain parallism and, when implemented in hardware, offer orders of magnitude speed up. However, neural networks implemented on a VLSI chip are planer architectures capable of efficient processing of linear vector signals rather than 2-D images. Therefore, for processing of images, a 3-D stack of neural-net ICs receiving planar inputs and consuming minimal power are required. Details of the circuits with chip architectures will be described with need to develop ultralow-power electronics. Further, use of the architecture in a system for high-speed processing will be illustrated.

  20. High aspect ratio 3D nanopatterning using Proton Beam Writing

    Science.gov (United States)

    van Kan, Jeroen A.

    2009-03-01

    Proton beam writing (PBW) is a new direct write lithography using MeV protons, and is unique because of its ability to fabricate 3D structures of high aspect ratio structures directly in resist material like PMMA, SU-8 and HSQ. The introduction by CIBA, Singapore of a dedicated PBW facility, capable of writing at the micro- and nano- scale has facilitated high aspect ratio nanostructuring. PBW has demontrated high aspect ratio walls in HSQ down to the 20nm level. In recent experiments details down to sub 20 nm have been achieved in PMMA. Monte-Carlo calculations have shown that structuring down to the nanometer level is feasible. All this is possible because of the virtual absence of proximity effects (unwanted resist exposure by stray secondary electrons). The design and performance of this unique nanoprobe facility will be discussed. Two potential fields of application (eg nanofluidics and nanowire integration) of PBW will be discussed. Currently nanofluidics devices have typically only one critical dimension below 100 nm. Here we will introduce PBW as a powerful technique to fabricate molds for replication of PDMS nanofluidic circuits down to the sub 100 nm level in two dimensions. Initial chips with dimension down to 150 nm have successfully been used to study DNA folding in quasi-1d nanochannels in tandem with fluorescence imaging. Since the size of these PDMS nanochannels is not limited by the PDMS or PBW further miniaturization down to the sub 100 nm level is a realistic goal and initial results will be discussed. Nanowires are a potential building block for nano-electronic devices, and one critical problem is the integration of nanowires to form contacts. Porous alumina templates and high energy ion-tracks have been used for the production of nanowire templates in a random orientation. Since PBW is the only true 3D direct write nanolithographic technique it can be used to fabricate nanowire templates in a controlled manner.

  1. High pressure behavior of 3d transition metal carbonates

    Science.gov (United States)

    Farfan, G. A.; Wang, S.; Boulard, E.; Mao, W. L.

    2012-12-01

    Understanding the behavior of carbon-rich phases in Earth's lower mantle is critical for modeling the global carbon cycle since the lower mantle may be the major repository for carbon in our planet. We were interested in the behavior of carbonates containing 3d transition metals, which can exhibit unusual properties at extreme conditions. Thus, we studied siderite (FeCO3) and rhodochrosite (MnCO3) at high pressure using a diamond anvil cell coupled with Raman spectroscopy, X-ray diffraction (XRD) and X-ray emission spectroscopy. In siderite we observed a high to low spin transition and associated volume collapse at approximately 46 GPa which is consistent with previous reports. Our Raman data show that the C-O bonds soften when the Fe2+ volume collapses (Farfan et al, 2012). In contrast, our XES results indicate that the Mn2+ in rhodochrosite does not undergo a spin transition like siderite up to 50 GPa. We observed a new Raman peak emerging above 48 GPa, which is a similar pressure at which a new structure was found in a previous XRD study.

  2. High resolution 3D imaging of synchrotron generated microbeams

    Energy Technology Data Exchange (ETDEWEB)

    Gagliardi, Frank M., E-mail: frank.gagliardi@wbrc.org.au [Alfred Health Radiation Oncology, The Alfred, Melbourne, Victoria 3004, Australia and School of Medical Sciences, RMIT University, Bundoora, Victoria 3083 (Australia); Cornelius, Iwan [Imaging and Medical Beamline, Australian Synchrotron, Clayton, Victoria 3168, Australia and Centre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales 2500 (Australia); Blencowe, Anton [Division of Health Sciences, School of Pharmacy and Medical Sciences, The University of South Australia, Adelaide, South Australia 5000, Australia and Division of Information Technology, Engineering and the Environment, Mawson Institute, University of South Australia, Mawson Lakes, South Australia 5095 (Australia); Franich, Rick D. [School of Applied Sciences and Health Innovations Research Institute, RMIT University, Melbourne, Victoria 3000 (Australia); Geso, Moshi [School of Medical Sciences, RMIT University, Bundoora, Victoria 3083 (Australia)

    2015-12-15

    Purpose: Microbeam radiation therapy (MRT) techniques are under investigation at synchrotrons worldwide. Favourable outcomes from animal and cell culture studies have proven the efficacy of MRT. The aim of MRT researchers currently is to progress to human clinical trials in the near future. The purpose of this study was to demonstrate the high resolution and 3D imaging of synchrotron generated microbeams in PRESAGE® dosimeters using laser fluorescence confocal microscopy. Methods: Water equivalent PRESAGE® dosimeters were fabricated and irradiated with microbeams on the Imaging and Medical Beamline at the Australian Synchrotron. Microbeam arrays comprised of microbeams 25–50 μm wide with 200 or 400 μm peak-to-peak spacing were delivered as single, cross-fire, multidirectional, and interspersed arrays. Imaging of the dosimeters was performed using a NIKON A1 laser fluorescence confocal microscope. Results: The spatial fractionation of the MRT beams was clearly visible in 2D and up to 9 mm in depth. Individual microbeams were easily resolved with the full width at half maximum of microbeams measured on images with resolutions of as low as 0.09 μm/pixel. Profiles obtained demonstrated the change of the peak-to-valley dose ratio for interspersed MRT microbeam arrays and subtle variations in the sample positioning by the sample stage goniometer were measured. Conclusions: Laser fluorescence confocal microscopy of MRT irradiated PRESAGE® dosimeters has been validated in this study as a high resolution imaging tool for the independent spatial and geometrical verification of MRT beam delivery.

  3. 双基地高频地波雷达三维曲面定位精度分析%Position accuracy for 3-D curved surface in bistatic high frequency surface wave radar

    Institute of Scientific and Technical Information of China (English)

    赵孔瑞; 周共健; 于长军; 权太范

    2012-01-01

    Bistatic high frequency surface wave radar (HFSWR) transmits vertically polarized high frequency wave propagating over coastal surface to detect nautical and aerial targets,the earth's curvature cannot be ignored.Target altitude formulations are established on a spherical coordinate system for different measurement subsets,the geometric dilution of precision (GDOP) is also conducted.Experiments demonstrate the GDOP of different subsets on variable flight altitude,the optimal distribution map of measurement subsets is also derived.%双基地高频地波雷达发射垂直极化电磁波沿海面绕射传播来探测海上和空中目标,导致地球曲率对探测精度的影响不可忽略.通过建立局部球面三维坐标系,在局部球面坐标系中求解不同测量子集下的目标高度解析式,并求解不同测量子集下的定位精度几何分布(geometric dilution of precision,GDOP).仿真分析目标在不同飞行高度时各测量子集的GDOP分布特性,最后得到飞行目标定位的最优测量子集分布图.

  4. A high efficiency all-PMOS charge pump for 3D NAND flash memory

    Science.gov (United States)

    Liyin, Fu; Yu, Wang; Qi, Wang; Zongliang, Huo

    2016-07-01

    For 3D vertical NAND flash memory, the charge pump output load is much larger than that of the planar NAND, resulting in the performance degradation of the conventional Dickson charge pump. Therefore, a novel all PMOS charge pump with high voltage boosting efficiency, large driving capability and high power efficiency for 3D V-NAND has been proposed. In this circuit, the Pelliconi structure is used to enhance the driving capability, two auxiliary substrate bias PMOS transistors are added to mitigate the body effect, and the degradation of the output voltage and boost efficiency caused by the threshold voltage drop is eliminated by dynamic gate control structure. Simulated results show that the proposed charge pump circuit can achieve the maximum boost efficiency of 86% and power efficiency of 50%. The output voltage of the proposed 9 stages charge pump can exceed 2 V under 2 MHz clock frequency in 2X nm 3D V-NAND technology. Our results provide guidance for the peripheral circuit design of high density 3D V-NAND integration.

  5. Generation of arbitrary order Bessel beams via 3D printed axicons at the terahertz frequency range.

    Science.gov (United States)

    Wei, Xuli; Liu, Changming; Niu, Liting; Zhang, Zhongqi; Wang, Kejia; Yang, Zhengang; Liu, Jinsong

    2015-12-20

    We present the generation of arbitrary order Bessel beams at 0.3 THz through the implementation of suitably designed axicons based on 3D printing technology. The helical axicons, which possess thickness gradients in both radial and azimuthal directions, can convert the incident Gaussian beam into a high-order Bessel beam with spiral phase structure. The evolution of the generated Bessel beams are characterized experimentally with a three-dimensional field scanner. Moreover, the topological charges carried by the high-order Bessel beams are determined by the fork-like interferograms. This 3D-printing-based Bessel beam generation technique is useful not only for THz imaging systems with zero-order Bessel beams but also for future orbital-angular-momentum-based THz free-space communication with higher-order Bessel beams. PMID:26837031

  6. 3D Shape Modeling Using High Level Descriptors

    DEFF Research Database (Denmark)

    Andersen, Vedrana

    The goal of this Ph.D. project is to investigate and improve the methods for describing the surface of 3D objects, with focus on modeling geometric texture on surfaces. Surface modeling being a large field of research, the work done during this project concentrated around a few smaller areas...

  7. A primary study of appropriate intraoral scanning frequency of single 3D image

    Science.gov (United States)

    Li, Hong; Lyu, Peijun; Sun, Yuchun; Wang, Yong; Liang, Xiaoyue

    2015-07-01

    Objective To make a quantitative analysis between sampling frequencies and micro-movement distance of mark points on tooth surfaces, and to provide a reference for sampling frequency settings of intraoral scanning systems. Methods Mark points affixed to the incisors of five subjects. In total, 3600 groups of tracking point coordinates were obtained with frequencies of 60, 150 and 300 Hz using an optical 3D tracking system. The data was then re-sampled to obtain coordinates at lower frequencies (5, 10, 15 and 20 Hz) at equal intervals of groups of tracking point coordinates. Change in distance (Δd) was defined as the change in position of a single v from one sampling time point to another, and was valued by clinical accuracy requirement (20-100μm). The curve equation was fit quantitatively between Δd median (M) and the sampling frequency (f). The difference between upper and lower incisor mark points were analyzed by a non-parametric test; α=0.05. Result When the frequency (f) was 60 Hz, upper jaw Δd median (M) and interquartile (Q) were 14.4 μm and 9.2 μm, respectively, while the lower Δd(M) and (Q) were 6.4 μm and 10.2 μm, respectively. Every Δd value was less than 100 μm, while 74% of Δd vales were less than 20 μm. Δd(M) and f satisfy the power curve equation: Δd(M)=0.526×f-0.979(f∈[5,300]). Significant differences of incisor feature points were noted between upper and lower jaws of the same subject (P<0.01). Conclusion Clinical accuracy can be met when the sampling frequency of the intraoral scanning system is 60 Hz.

  8. 3-D Experimental Fracture Analysis at High Temperature

    Energy Technology Data Exchange (ETDEWEB)

    John H. Jackson; Albert S. Kobayashi

    2001-09-14

    T*e, which is an elastic-plastic fracture parameter based on incremental theory of plasticity, was determined numerically and experimentally. The T*e integral of a tunneling crack in 2024-T3 aluminum, three point bend specimen was obtained through a hybrid analysis of moire interferometry and 3-D elastic-plastic finite element analysis. The results were verified by the good agreement between the experimentally and numerically determined T*e on the specimen surface.

  9. Compute extremely low-frequency electromagnetic field exposure by 3-D impendance method

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A 3-D impedance method has been introduced to compute the electric currents induced in a human body exposed to extremely low-frequency electromagnetic field.The 3-D impedance method has been deduced from Maxwell equations and is put into the computation and simulation effectively to the visible human body model, which has 196×114×626 cells and more than 40 types of tissues.As the result, two representative cases are investigated.One is exposure of the human body to 100 μT (1 000 mG), the limit recommended by the International Commission on Non-Ionizing Radiation Protection for the public and the other one is the exposure of human body to 0.4 μT (4 mG), the level at which a statistical link appears with a doubled risk of development of childhood leukaemia.The distribution of induced current density can be obtained and the maximum of induced current are found to be 16 mA/m2 and 0.07 mA/m2.

  10. High Current Density 2D/3D Esaki Tunnel Diodes

    OpenAIRE

    Krishnamoorthy, Sriram; Lee II, Edwin W.; Lee, Choong Hee; Zhang, Yuewei; McCulloch, William D.; Johnson, Jared M.; Hwang, Jinwoo; Wu, Yiying; Rajan, Siddharth

    2016-01-01

    The integration of two-dimensional materials such as transition metal dichalcogenides with bulk semiconductors offer interesting opportunities for 2D/3D heterojunction-based novel device structures without any constraints of lattice matching. By exploiting the favorable band alignment at the GaN/MoS2 heterojunction, an Esaki interband tunnel diode is demonstrated by transferring large area, Nb-doped, p-type MoS2 onto heavily n-doped GaN. A peak current density of 446 A/cm2 with repeatable roo...

  11. High-Performance 3D Articulated Robot Display

    Science.gov (United States)

    Powell, Mark W.; Torres, Recaredo J.; Mittman, David S.; Kurien, James A.; Abramyan, Lucy

    2011-01-01

    In the domain of telerobotic operations, the primary challenge facing the operator is to understand the state of the robotic platform. One key aspect of understanding the state is to visualize the physical location and configuration of the platform. As there is a wide variety of mobile robots, the requirements for visualizing their configurations vary diversely across different platforms. There can also be diversity in the mechanical mobility, such as wheeled, tracked, or legged mobility over surfaces. Adaptable 3D articulated robot visualization software can accommodate a wide variety of robotic platforms and environments. The visualization has been used for surface, aerial, space, and water robotic vehicle visualization during field testing. It has been used to enable operations of wheeled and legged surface vehicles, and can be readily adapted to facilitate other mechanical mobility solutions. The 3D visualization can render an articulated 3D model of a robotic platform for any environment. Given the model, the software receives real-time telemetry from the avionics system onboard the vehicle and animates the robot visualization to reflect the telemetered physical state. This is used to track the position and attitude in real time to monitor the progress of the vehicle as it traverses its environment. It is also used to monitor the state of any or all articulated elements of the vehicle, such as arms, legs, or control surfaces. The visualization can also render other sorts of telemetered states visually, such as stress or strains that are measured by the avionics. Such data can be used to color or annotate the virtual vehicle to indicate nominal or off-nominal states during operation. The visualization is also able to render the simulated environment where the vehicle is operating. For surface and aerial vehicles, it can render the terrain under the vehicle as the avionics sends it location information (GPS, odometry, or star tracking), and locate the vehicle

  12. Highly functional tunnelling devices integrated in 3D

    DEFF Research Database (Denmark)

    Wernersson, Lars-Erik; Lind, Erik; Lindström, Peter;

    2003-01-01

    circuit in order to optimize the performance of the device. In addition to the tunnelling structure below the grating, these transistors may be integrated in 3D by the introduction of another tunnelling structure directly over the metal grating. In the integrated device structure, the gate acts......We present a new technology for integrating tunnelling devices in three dimensions. These devices are fabricated by the combination of the growth of semiconductor heterostructures with the controlled introduction of metallic elements into an epitaxial layer by an overgrowth technique. First, we use...... simultaneously on both tunnelling structures and the obtained characteristics are the result of the interplay between the two tunnelling structures and the gate. An equivalent circuit model is developed and we show how this interaction influences the current-voltage characteristics. The gate may be used...

  13. Efficient 3D frequency response modeling with spectral accuracy by the rapid expansion method

    KAUST Repository

    Chu, Chunlei

    2012-07-01

    Frequency responses of seismic wave propagation can be obtained either by directly solving the frequency domain wave equations or by transforming the time domain wavefields using the Fourier transform. The former approach requires solving systems of linear equations, which becomes progressively difficult to tackle for larger scale models and for higher frequency components. On the contrary, the latter approach can be efficiently implemented using explicit time integration methods in conjunction with running summations as the computation progresses. Commonly used explicit time integration methods correspond to the truncated Taylor series approximations that can cause significant errors for large time steps. The rapid expansion method (REM) uses the Chebyshev expansion and offers an optimal solution to the second-order-in-time wave equations. When applying the Fourier transform to the time domain wavefield solution computed by the REM, we can derive a frequency response modeling formula that has the same form as the original time domain REM equation but with different summation coefficients. In particular, the summation coefficients for the frequency response modeling formula corresponds to the Fourier transform of those for the time domain modeling equation. As a result, we can directly compute frequency responses from the Chebyshev expansion polynomials rather than the time domain wavefield snapshots as do other time domain frequency response modeling methods. When combined with the pseudospectral method in space, this new frequency response modeling method can produce spectrally accurate results with high efficiency. © 2012 Society of Exploration Geophysicists.

  14. Implementation of low communication frequency 3D FFT algorithm for ultra-large-scale micromagnetics simulation

    Science.gov (United States)

    Tsukahara, Hiroshi; Iwano, Kaoru; Mitsumata, Chiharu; Ishikawa, Tadashi; Ono, Kanta

    2016-10-01

    We implement low communication frequency three-dimensional fast Fourier transform algorithms on micromagnetics simulator for calculations of a magnetostatic field which occupies a significant portion of large-scale micromagnetics simulation. This fast Fourier transform algorithm reduces the frequency of all-to-all communications from six to two times. Simulation times with our simulator show high scalability in parallelization, even if we perform the micromagnetics simulation using 32 768 physical computing cores. This low communication frequency fast Fourier transform algorithm enables world largest class micromagnetics simulations to be carried out with over one billion calculation cells.

  15. Inclusion of high resolution MODIS maps on a 3D tropospheric water vapor GPS tomography model

    Science.gov (United States)

    Benevides, Pedro; Catalao, Joao; Nico, Giovanni; Miranda, Pedro M. A.

    2015-10-01

    Observing the water vapor distribution on the troposphere remains a challenge for the weather forecast. Radiosondes provide precise water vapor profiles of the troposphere, but lack geographical and temporal coverage, while satellite meteorological maps have good spatial resolution but even poorer temporal resolution. GPS has proved its capacity to measure the integrated water vapor in all weather conditions with high temporal sampling frequency. However these measurements lack a vertical water vapor discretization. Reconstruction of the slant path GPS observation to the satellite allows oblique water vapor measurements. Implementation of a 3D grid of voxels along the troposphere over an area where GPS stations are available enables the observation ray tracing. A relation between the water vapor density and the distanced traveled inside the voxels is established, defining GPS tomography. An inverse problem formulation is needed to obtain a water vapor solution. The combination of precipitable water vapor (PWV) maps obtained from MODIS satellite data with the GPS tomography is performed in this work. The MODIS PWV maps can have 1 or 5 km pixel resolution, being obtained 2 times per day in the same location at most. The inclusion of MODIS PWV maps provides an enhanced horizontal resolution for the tomographic solution and benefits the stability of the inversion problem. A 3D tomographic grid was adjusted over a regional area covering Lisbon, Portugal, where a GNSS network of 9 receivers is available. Radiosonde measurements in the area are used to evaluate the 3D water vapor tomography maps.

  16. Imaging of 3D Ocean Turbulence Microstructure Using Low Frequency Acoustic Waves

    Science.gov (United States)

    Minakov, Alexander; Kolyukhin, Dmitriy; Keers, Henk

    2015-04-01

    In the past decade the technique of imaging the ocean structure with low-frequency signal (Hz), produced by air-guns and typically employed during conventional multichannel seismic data acquisition, has emerged. The method is based on extracting and stacking the acoustic energy back-scattered by the ocean temperature and salinity micro- and meso-structure (1 - 100 meters). However, a good understanding of the link between the scattered wavefield utilized by the seismic oceanography and physical processes in the ocean is still lacking. We describe theory and the numerical implementation of a 3D time-dependent stochastic model of ocean turbulence. The velocity and temperature are simulated as homogeneous Gaussian isotropic random fields with the Kolmogorov-Obukhov energy spectrum in the inertial subrange. Numerical modeling technique is employed for sampling of realizations of random fields with a given spatial-temporal spectral tensor. The model used is shown to be representative for a wide range of scales. Using this model, we provide a framework to solve the forward and inverse acoustic scattering problem using marine seismic data. Our full-waveform inversion method is based on the ray-Born approximation which is specifically suitable for the modelling of small velocity perturbations in the ocean. This is illustrated by showing a good match between synthetic seismograms computed using ray-Born and synthetic seismograms produced with a more computationally expensive finite-difference method.

  17. A 3D CZT high resolution detector for x- and gamma-ray astronomy

    DEFF Research Database (Denmark)

    Kuvvetli, Irfan; Budtz-Jørgensen, Carl; Zappettini, A.;

    2014-01-01

    At DTU Space we have developed a high resolution three dimensional (3D) position sensitive CZT detector for high energy astronomy. The design of the 3D CZT detector is based on the CZT Drift Strip detector principle. The position determination perpendicular to the anode strips is performed using...

  18. High-strength cellular ceramic composites with 3D microarchitecture

    OpenAIRE

    Bauer, Jens; Hengsbach, Stefan; Tesari, Iwiza; Schwaiger, Ruth; Kraft, Oliver

    2014-01-01

    It has been a long-standing effort to create materials with low density but high strength. Technical foams are very light, but compared with bulk materials, their strength is quite low because of their random structure. Natural lightweight materials, such as bone, are cellular solids with optimized architecture. They are structured hierarchically and actually consist of nanometer-size building blocks, providing a benefit from mechanical size effects. In this paper, we demonstrate that materia...

  19. Measuring the 3D shape of high temperature objects using blue sinusoidal structured light

    Science.gov (United States)

    Zhao, Xianling; Liu, Jiansheng; Zhang, Huayu; Wu, Yingchun

    2015-12-01

    The visible light radiated by some high temperature objects (less than 1200 °C) almost lies in the red and infrared waves. It will interfere with structured light projected on a forging surface if phase measurement profilometry (PMP) is used to measure the shapes of objects. In order to obtain a clear deformed pattern image, a 3D measurement method based on blue sinusoidal structured light is proposed in this present work. Moreover, a method for filtering deformed pattern images is presented for correction of the unwrapping phase. Blue sinusoidal phase-shifting fringe pattern images are projected on the surface by a digital light processing (DLP) projector, and then the deformed patterns are captured by a 3-CCD camera. The deformed pattern images are separated into R, G and B color components by the software. The B color images filtered by a low-pass filter are used to calculate the fringe order. Consequently, the 3D shape of a high temperature object is obtained by the unwrapping phase and the calibration parameter matrixes of the DLP projector and 3-CCD camera. The experimental results show that the unwrapping phase is completely corrected with the filtering method by removing the high frequency noise from the first harmonic of the B color images. The measurement system can complete the measurement in a few seconds with a relative error of less than 1 : 1000.

  20. Measuring the 3D shape of high temperature objects using blue sinusoidal structured light

    International Nuclear Information System (INIS)

    The visible light radiated by some high temperature objects (less than 1200 °C) almost lies in the red and infrared waves. It will interfere with structured light projected on a forging surface if phase measurement profilometry (PMP) is used to measure the shapes of objects. In order to obtain a clear deformed pattern image, a 3D measurement method based on blue sinusoidal structured light is proposed in this present work. Moreover, a method for filtering deformed pattern images is presented for correction of the unwrapping phase. Blue sinusoidal phase-shifting fringe pattern images are projected on the surface by a digital light processing (DLP) projector, and then the deformed patterns are captured by a 3-CCD camera. The deformed pattern images are separated into R, G and B color components by the software. The B color images filtered by a low-pass filter are used to calculate the fringe order. Consequently, the 3D shape of a high temperature object is obtained by the unwrapping phase and the calibration parameter matrixes of the DLP projector and 3-CCD camera. The experimental results show that the unwrapping phase is completely corrected with the filtering method by removing the high frequency noise from the first harmonic of the B color images. The measurement system can complete the measurement in a few seconds with a relative error of less than 1 : 1000. (paper)

  1. TORT-TD/ATTICA3D: a coupled neutron transport and thermal hydraulics code system for 3-D transient analysis of gas cooled high temperature reactors

    International Nuclear Information System (INIS)

    Comprehensive safety studies of high temperature gas cooled reactors (HTR) require full three dimensional coupled treatments of both neutron kinetics and thermal-hydraulics. In a common effort, GRS and IKE developed the coupled code system TORT-TD/ATTICA3D for pebble bed type HTR that connects the 3-D transient discrete-ordinates transport code TORT-TD with the 3-D porous medium thermal-hydraulics code ATTICA3D. In this paper, the physical models and calculation capabilities of TORT-TD and ATTICA3D are presented, focusing on model improvements in ATTICA3D and extensions made in TORT-TD related to HTR application. For first applications, the OECD/NEA/NSC PBMR-400 benchmark has been chosen. Results obtained with TORT-TD/ATTICA3D will be shown for transient exercises, e.g. control rod withdrawal and a control rod ejection. Results are compared to other benchmark participants' solutions with special focus on fuel temperature modelling features of ATTICA3D. The provided “grey-curtain” nuclear cross section libraries have been used. First results on 3-D effects during a control rod withdrawal transient will be presented. (author)

  2. Application of high resolution 2D/3D spectral induced polarization (SIP) in metalliferous ore exploration

    Science.gov (United States)

    Chen, R.; Zhao, X.; Yao, H.; He, X.; Zeng, P.; Chang, F.; Yang, Y.; Zhang, X.; Xi, X.; He, L.

    2015-12-01

    Induced polarization (IP) is a powerful tool in metalliferous ore exploration. However, there are many sources, such as clay and graphite, which can generate IP anomaly. Spectral induced polarization (SIP) measures IP response on a wide frequency range. This method provides a way to discriminate IP response generated by metalliferous ore or other objects. The best way to explore metalliferous ore is 3D SIP exploration. However, if we consider the exploration cost and efficiency, we can use SIP profiling to find an anomaly, and then use 2D/3D SIP sounding to characterize the anomaly. Based on above idea, we used a large-scale distributed SIP measurement system which can realize 800 sounding sites in one direction at the same time. This system can be used for SIP profiling, 2D/3D SIP sounding with high efficiency, high resolution, and large depth of investigation (> 1000 m). Qiushuwan copper - molybdenum deposit is located in Nanyang city, Henan province, China. It is only a middle-size deposit although over 100 holes were drilled and over 40 years of exploration were spent because of very complex geological setting. We made SIP measurement over 100 rock and ore samples to discriminate IP responses of ore and rock containing graphite. Then we carried out 7 lines of 2D SIP exploration with the depth of investigation great than 1000 m. The minimum electode spacing for potential difference is only 20 m. And we increase the spacing of current electodes at linear scale. This acquisition setting ensures high density data acquired and high quality data acquisition. Modeling and inversion result proves that we can get underground information with high resolution by our method. Our result shows that there exists a strong SIP response related to ore body in depth > 300 m. Pseudo-3D inversion of five 2D SIP sounding lines shows the location and size of IP anomaly. The new drillings based our result found a big copper-molybdenum ore body in new position with depth > 300 m and

  3. RAPID COMMUNICATION: A novel time frequency-based 3D Lissajous figure method and its application to the determination of oxygen saturation from the photoplethysmogram

    Science.gov (United States)

    Addison, Paul S.; Watson, James N.

    2004-11-01

    We present a novel time-frequency method for the measurement of oxygen saturation using the photoplethysmogram (PPG) signals from a standard pulse oximeter machine. The method utilizes the time-frequency transformation of the red and infrared PPGs to derive a 3D Lissajous figure. By selecting the optimal Lissajous, the method provides an inherently robust basis for the determination of oxygen saturation as regions of the time-frequency plane where high- and low-frequency signal artefacts are to be found are automatically avoided.

  4. Serum induced degradation of 3D DNA box origami observed by high speed atomic force microscope

    DEFF Research Database (Denmark)

    Jiang, Zaixing; Zhang, Shuai; Yang, Chuanxu;

    2015-01-01

    DNA box origami in serum using high-speed atomic force microscope optimized for imaging 3D DNA origami in real time. The time resolution allows characterizing the stages of serum effects on individual 3D DNA box origami with nanometer resolution. Our results indicate that the whole digest process...

  5. Creating Realistic 3D Graphics with Excel at High School--Vector Algebra in Practice

    Science.gov (United States)

    Benacka, Jan

    2015-01-01

    The article presents the results of an experiment in which Excel applications that depict rotatable and sizable orthographic projection of simple 3D figures with face overlapping were developed with thirty gymnasium (high school) students of age 17-19 as an introduction to 3D computer graphics. A questionnaire survey was conducted to find out…

  6. 3-D P- and S-wave velocity structure and low-frequency earthquake locations in the Parkfield, California region

    Science.gov (United States)

    Zeng, Xiangfang; Thurber, Clifford H.; Shelly, David R.; Harrington, Rebecca M.; Cochran, Elizabeth S.; Bennington, Ninfa L.; Peterson, Dana; Guo, Bin; McClement, Kara

    2016-09-01

    To refine the 3-D seismic velocity model in the greater Parkfield, California region, a new data set including regular earthquakes, shots, quarry blasts and low-frequency earthquakes (LFEs) was assembled. Hundreds of traces of each LFE family at two temporary arrays were stacked with time-frequency domain phase weighted stacking method to improve signal-to-noise ratio. We extend our model resolution to lower crustal depth with LFE data. Our result images not only previously identified features but also low velocity zones (LVZs) in the area around the LFEs and the lower crust beneath the southern Rinconada Fault. The former LVZ is consistent with high fluid pressure that can account for several aspects of LFE behaviour. The latter LVZ is consistent with a high conductivity zone in magnetotelluric studies. A new Vs model was developed with S picks that were obtained with a new autopicker. At shallow depth, the low Vs areas underlie the strongest shaking areas in the 2004 Parkfield earthquake. We relocate LFE families and analyse the location uncertainties with the NonLinLoc and tomoDD codes. The two methods yield similar results.

  7. Methodology of High Accuracy and Resolution 3D Geological Model Generation and Application

    Institute of Scientific and Technical Information of China (English)

    吴键; 曹代勇; 邓爱居; 李东津; 蒋涛; 翟光华

    2004-01-01

    By generating a high accuracy and high resolution geological model in Liuchu oil field, the technique of geological modeling is expanded and involved in primary geological study, making the sand bodies and reservoir be easily described in detail. The 3D visualization and 3D interactive editing of geological structure model are the key for modeling procedure. And a high accuracy and resolution geological model has been well applied in optimizing the production scheme.

  8. Ultra-compact, High Resolution, LADAR system for 3D Imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SiWave proposes to develop an innovative, ultra-compact, high resolution, long range LADAR system to produce a 3D map of the exterior of any object in space such as...

  9. EXPLORING THE POTENTIAL OF AERIAL PHOTOGRAMMETRY FOR 3D MODELLING OF HIGH-ALPINE ENVIRONMENTS

    Directory of Open Access Journals (Sweden)

    K. Legat

    2016-03-01

    Based on the very promising results, some general recommendations for aerial photogrammetry processing in high-alpine areas are made to achieve best possible accuracy of the final 3D-, 2.5D- and 2D products.

  10. High-resolution laser radar for 3D imaging in artwork cataloging, reproduction, and restoration

    Science.gov (United States)

    Ricci, Roberto; Fantoni, Roberta; Ferri de Collibus, Mario; Fornetti, Giorgio G.; Guarneri, Massimiliano; Poggi, Claudio

    2003-10-01

    A high resolution Amplitude Modulated Laser Radar (AM-LR) sensor has recently been developed, aimed at accurately reconstructing 3D digital models of real targets, either single objects or complex scenes. The sensor sounding beam can be swept linearly across the object or circularly around it, by placing the object on a controlled rotating platform, enabling to obtain respectively linear and cylindrical range maps. Both amplitude and phase shift of the modulating wave of back-scattered light are collected and processed, providing respectively a shade-free, high resolution, photographic-like picture and accurate range data in the form of a range image. The resolution of range measurements depends mainly on the laser modulation frequency, provided that the power of the backscattered light reaching the detector is at least a few nW (current best performances are ~100 μm). The complete object surface can be reconstructed from the sampled points by using specifically developed software tools. The system has been successfully applied to scan different types of real surfaces (stone, wood, alloys, bones), with relevant applications in different fields, ranging from industrial machining to medical diagnostics, to vision in hostile environments. Examples of artwork reconstructed models (pottery, marble statues) are presented and the relevance of this technology for reverse engineering applied to cultural heritage conservation and restoration are discussed. Final 3D models can be passed to numeric control machines for rapid-prototyping, exported in standard formats for CAD/CAM purposes and made available on the Internet by adopting a virtual museum paradigm, thus possibly enabling specialists to perform remote inspections on high resolution digital reproductions of hardly accessible masterpieces.

  11. BioSig3D: High Content Screening of Three-Dimensional Cell Culture Models.

    Directory of Open Access Journals (Sweden)

    Cemal Cagatay Bilgin

    Full Text Available BioSig3D is a computational platform for high-content screening of three-dimensional (3D cell culture models that are imaged in full 3D volume. It provides an end-to-end solution for designing high content screening assays, based on colony organization that is derived from segmentation of nuclei in each colony. BioSig3D also enables visualization of raw and processed 3D volumetric data for quality control, and integrates advanced bioinformatics analysis. The system consists of multiple computational and annotation modules that are coupled together with a strong use of controlled vocabularies to reduce ambiguities between different users. It is a web-based system that allows users to: design an experiment by defining experimental variables, upload a large set of volumetric images into the system, analyze and visualize the dataset, and either display computed indices as a heatmap, or phenotypic subtypes for heterogeneity analysis, or download computed indices for statistical analysis or integrative biology. BioSig3D has been used to profile baseline colony formations with two experiments: (i morphogenesis of a panel of human mammary epithelial cell lines (HMEC, and (ii heterogeneity in colony formation using an immortalized non-transformed cell line. These experiments reveal intrinsic growth properties of well-characterized cell lines that are routinely used for biological studies. BioSig3D is being released with seed datasets and video-based documentation.

  12. BioSig3D: High Content Screening of Three-Dimensional Cell Culture Models.

    Science.gov (United States)

    Bilgin, Cemal Cagatay; Fontenay, Gerald; Cheng, Qingsu; Chang, Hang; Han, Ju; Parvin, Bahram

    2016-01-01

    BioSig3D is a computational platform for high-content screening of three-dimensional (3D) cell culture models that are imaged in full 3D volume. It provides an end-to-end solution for designing high content screening assays, based on colony organization that is derived from segmentation of nuclei in each colony. BioSig3D also enables visualization of raw and processed 3D volumetric data for quality control, and integrates advanced bioinformatics analysis. The system consists of multiple computational and annotation modules that are coupled together with a strong use of controlled vocabularies to reduce ambiguities between different users. It is a web-based system that allows users to: design an experiment by defining experimental variables, upload a large set of volumetric images into the system, analyze and visualize the dataset, and either display computed indices as a heatmap, or phenotypic subtypes for heterogeneity analysis, or download computed indices for statistical analysis or integrative biology. BioSig3D has been used to profile baseline colony formations with two experiments: (i) morphogenesis of a panel of human mammary epithelial cell lines (HMEC), and (ii) heterogeneity in colony formation using an immortalized non-transformed cell line. These experiments reveal intrinsic growth properties of well-characterized cell lines that are routinely used for biological studies. BioSig3D is being released with seed datasets and video-based documentation. PMID:26978075

  13. 3D Modeling Activity for Novel High Power Electron Guns at SLAC

    CERN Document Server

    Krasnykh, Anatoly K

    2003-01-01

    The next generation of powerful electronic devices requires new approaches to overcome the known limitations of existing tube technology. Multi-beam and sheet beam approaches are novel concepts for the high power microwave devices. Direct and indirect modeling methods are being developed at SLAC to meet the new requirements in the 3D modeling. The direct method of solving of Poisson's equations for the multi-beam and sheet beam guns is employed in the TOPAZ 3D tool. The combination of TOPAZ 2D and EGUN (in the beginning) with MAFIA 3D and MAGIC 3D (at the end) is used in an indirect method to model the high power electron guns. Both methods complement each other to get reliable representation of the beam trajectories. Several gun ideas are under consideration at the present time. The collected results of these simulations are discussed.

  14. High-resolution MRI of the labyrinth. Optimization of scan parameters with 3D-FSE

    International Nuclear Information System (INIS)

    The aim of our study was to optimize the parameters of high-resolution MRI of the labyrinth with a 3D fast spin-echo (3D-FSE) sequence. We investigated repetition time (TR), echo time (TE), Matrix, field of view (FOV), and coil selection in terms of CNR (contrast-to-noise ratio) and SNR (signal-to-noise ratio) by comparing axial images and/or three-dimensional images. The optimal 3D-FSE sequence parameters were as follows: 1.5 Tesla MR unit (Signa LX, GE Medical Systems), 3D-FSE sequence, dual 3-inch surface coil, acquisition time=12.08 min, TR=5000 msec, TE=300 msec, 3 number of excitations (NEX), FOV=12 cm, matrix=256 x 256, slice thickness=0.5 mm/0.0 sp, echo train=64, bandwidth=±31.5 kHz. High-resolution MRI of the labyrinth using the optimized 3D-FSE sequence parameters permits visualization of important anatomic details (such as scala tympani and scala vestibuli), making it possible to determine inner ear anomalies and the patency of cochlear turns. To obtain excellent heavily T2-weighted axial and three-dimensional images in the labyrinth, high CNR, SNR, and spatial resolution are significant factors at the present time. Furthermore, it is important not only to optimize the scan parameters of 3D-FSE but also to select an appropriate coil for high-resolution MRI of the labyrinth. (author)

  15. 3D nanochannel electroporation for high-throughput cell transfection with high uniformity and dosage control

    Science.gov (United States)

    Chang, Lingqian; Bertani, Paul; Gallego-Perez, Daniel; Yang, Zhaogang; Chen, Feng; Chiang, Chiling; Malkoc, Veysi; Kuang, Tairong; Gao, Keliang; Lee, L. James; Lu, Wu

    2015-12-01

    Of great interest to modern medicine and biomedical research is the ability to inject individual target cells with the desired genes or drug molecules. Some advances in cell electroporation allow for high throughput, high cell viability, or excellent dosage control, yet no platform is available for the combination of all three. In an effort to solve this problem, here we show a ``3D nano-channel electroporation (NEP) chip'' on a silicon platform designed to meet these three criteria. This NEP chip can simultaneously deliver the desired molecules into 40 000 cells per cm2 on the top surface of the device. Each 650 nm pore aligns to a cell and can be used to deliver extremely small biological elements to very large plasmids (>10 kbp). When compared to conventional bulk electroporation (BEP), the NEP chip shows a 20 fold improvement in dosage control and uniformity, while still maintaining high cell viability (>90%) even in cells such as cardiac cells which are characteristically difficult to transfect. This high-throughput 3D NEP system provides an innovative and medically valuable platform with uniform and reliable cellular transfection, allowing for a steady supply of healthy, engineered cells.Of great interest to modern medicine and biomedical research is the ability to inject individual target cells with the desired genes or drug molecules. Some advances in cell electroporation allow for high throughput, high cell viability, or excellent dosage control, yet no platform is available for the combination of all three. In an effort to solve this problem, here we show a ``3D nano-channel electroporation (NEP) chip'' on a silicon platform designed to meet these three criteria. This NEP chip can simultaneously deliver the desired molecules into 40 000 cells per cm2 on the top surface of the device. Each 650 nm pore aligns to a cell and can be used to deliver extremely small biological elements to very large plasmids (>10 kbp). When compared to conventional bulk

  16. Mussel-inspired biopolymer modified 3D graphene foam for enzyme immobilization and high performance biosensor

    International Nuclear Information System (INIS)

    Highlights: • Outstanding 3D biosensing platform was explored for reagentless detection of H2O2. • Monolithic 3D graphene foam served as a freestanding electrode scaffold. • MB-CNTs hybrid assembled on 3D graphene as efficient electron mediator. • Mussel inspired polydopamine as a green linker for enzyme immobilization. - Abstract: A simple and versatile method is described to construct high performance three-dimensional (3D) graphene-based enzyme biosensor. Monolithic and macroporous 3D graphene foam grown by chemical vapor deposition (CVD) was used as a freestanding electrode for co-immobilization of horseradish peroxidase (HRP) and a commonly used redox mediator, methylene blue (MB). Carbon nanotubes (CNTs) were employed as carriers of MB molecules to immobilize them on 3D graphene surface through strong π-π stacking force. Mussel-inspired biopolymer polydopamine (PDA) was formed by in-situ polymerization and served as a green linker, which could covalently graft HRP on the surface of 3D graphene/MB-CNTs electrode. In addition, PDA layer could also effectively prevent the leakage of inner electron mediators. Owing to the 3D macroporous architecture, exceptional properties of graphene and surface-bound mediators, the biosensor demonstrated outstanding performance for reagentless detection of H2O2 in terms of wide linear range (0.2 μM to 1.1 mM), high sensitivity (227.8 μA mM−1 cm−2), low detection limit (58.0 nM), and fast response (reaching 95% of the steady current within 3 s). The biosensor exhibited high reproducibility and stability

  17. Frequency-Stable Offset-Locked Lasers for ASCENDS and 3D Winds Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose the potential to develop significant improvements to size, weight, and prime power requirements of front-end cw lasers and associated frequency...

  18. A 3D tunable and multi-frequency graphene plasmonic cloak

    KAUST Repository

    Farhat, Mohamed Dhia Eddine

    2013-01-01

    We demonstrate the possibility of cloaking three-dimensional objects at multi-frequencies in the far-infrared part of the spectrum. The proposed cloaking mechanism exploits graphene layers wrapped around the object to be concealed. Graphene layers are doped via a variable external voltage difference permitting continuous tuning of the cloaking frequencies. Particularly, two configurations are investigated: (i) Only one graphene layer is used to suppress the scattering from a dielectric sphere. (ii) Several of these layers biased at different gate voltages are used to achieve a multi-frequency cloak. These frequencies can be set independently. The proposed cloak\\'s functionality is verified by near- and far-field computations. By considering geometry and material parameters that are realizable by practical experiments, we contribute to the development of graphene based plasmonic applications that may find use in disruptive photonic technologies. © 2013 Optical Society of America.

  19. 3D nanochannel electroporation for high-throughput cell transfection with high uniformity and dosage control.

    Science.gov (United States)

    Chang, Lingqian; Bertani, Paul; Gallego-Perez, Daniel; Yang, Zhaogang; Chen, Feng; Chiang, Chiling; Malkoc, Veysi; Kuang, Tairong; Gao, Keliang; Lee, L James; Lu, Wu

    2016-01-01

    Of great interest to modern medicine and biomedical research is the ability to inject individual target cells with the desired genes or drug molecules. Some advances in cell electroporation allow for high throughput, high cell viability, or excellent dosage control, yet no platform is available for the combination of all three. In an effort to solve this problem, here we show a "3D nano-channel electroporation (NEP) chip" on a silicon platform designed to meet these three criteria. This NEP chip can simultaneously deliver the desired molecules into 40,000 cells per cm(2) on the top surface of the device. Each 650 nm pore aligns to a cell and can be used to deliver extremely small biological elements to very large plasmids (>10 kbp). When compared to conventional bulk electroporation (BEP), the NEP chip shows a 20 fold improvement in dosage control and uniformity, while still maintaining high cell viability (>90%) even in cells such as cardiac cells which are characteristically difficult to transfect. This high-throughput 3D NEP system provides an innovative and medically valuable platform with uniform and reliable cellular transfection, allowing for a steady supply of healthy, engineered cells. PMID:26309218

  20. 3D nanochannel electroporation for high-throughput cell transfection with high uniformity and dosage control.

    Science.gov (United States)

    Chang, Lingqian; Bertani, Paul; Gallego-Perez, Daniel; Yang, Zhaogang; Chen, Feng; Chiang, Chiling; Malkoc, Veysi; Kuang, Tairong; Gao, Keliang; Lee, L James; Lu, Wu

    2016-01-01

    Of great interest to modern medicine and biomedical research is the ability to inject individual target cells with the desired genes or drug molecules. Some advances in cell electroporation allow for high throughput, high cell viability, or excellent dosage control, yet no platform is available for the combination of all three. In an effort to solve this problem, here we show a "3D nano-channel electroporation (NEP) chip" on a silicon platform designed to meet these three criteria. This NEP chip can simultaneously deliver the desired molecules into 40,000 cells per cm(2) on the top surface of the device. Each 650 nm pore aligns to a cell and can be used to deliver extremely small biological elements to very large plasmids (>10 kbp). When compared to conventional bulk electroporation (BEP), the NEP chip shows a 20 fold improvement in dosage control and uniformity, while still maintaining high cell viability (>90%) even in cells such as cardiac cells which are characteristically difficult to transfect. This high-throughput 3D NEP system provides an innovative and medically valuable platform with uniform and reliable cellular transfection, allowing for a steady supply of healthy, engineered cells.

  1. Preliminary results of a low-frequency 3D-SAR approach for glacier volume mapping

    OpenAIRE

    Henke*, D; Meier, E

    2010-01-01

    First experimental results with a low-frequency, ultra widebad (UWB) radar for estimating the height of glacier beds are illustrated. We use a 3-dimensional Time-Domain Back-Projection (TDBP) algorithm which incorporates the influence of the refractivity of ice to reconstruct the glacier bed of the Aletsch Glacier in the Swiss Alps using several CARABAS data sets. As the results indicate, the proposed method underlines the ability of low-frequency Synthetic Aperture Radar (SAR) to penetrate i...

  2. High-purity 3D nano-objects grown by focused-electron-beam induced deposition.

    Science.gov (United States)

    Córdoba, Rosa; Sharma, Nidhi; Kölling, Sebastian; Koenraad, Paul M; Koopmans, Bert

    2016-09-01

    To increase the efficiency of current electronics, a specific challenge for the next generation of memory, sensing and logic devices is to find suitable strategies to move from two- to three-dimensional (3D) architectures. However, the creation of real 3D nano-objects is not trivial. Emerging non-conventional nanofabrication tools are required for this purpose. One attractive method is focused-electron-beam induced deposition (FEBID), a direct-write process of 3D nano-objects. Here, we grow 3D iron and cobalt nanopillars by FEBID using diiron nonacarbonyl Fe2(CO)9, and dicobalt octacarbonyl Co2(CO)8, respectively, as starting materials. In addition, we systematically study the composition of these nanopillars at the sub-nanometer scale by atom probe tomography, explicitly mapping the homogeneity of the radial and longitudinal composition distributions. We show a way of fabricating high-purity 3D vertical nanostructures of ∼50 nm in diameter and a few micrometers in length. Our results suggest that the purity of such 3D nanoelements (above 90 at% Fe and above 95 at% Co) is directly linked to their growth regime, in which the selected deposition conditions are crucial for the final quality of the nanostructure. Moreover, we demonstrate that FEBID and the proposed characterization technique not only allow for growth and chemical analysis of single-element structures, but also offers a new way to directly study 3D core-shell architectures. This straightforward concept could establish a promising route to the design of 3D elements for future nano-electronic devices. PMID:27454835

  3. High-purity 3D nano-objects grown by focused-electron-beam induced deposition

    Science.gov (United States)

    Córdoba, Rosa; Sharma, Nidhi; Kölling, Sebastian; Koenraad, Paul M.; Koopmans, Bert

    2016-09-01

    To increase the efficiency of current electronics, a specific challenge for the next generation of memory, sensing and logic devices is to find suitable strategies to move from two- to three-dimensional (3D) architectures. However, the creation of real 3D nano-objects is not trivial. Emerging non-conventional nanofabrication tools are required for this purpose. One attractive method is focused-electron-beam induced deposition (FEBID), a direct-write process of 3D nano-objects. Here, we grow 3D iron and cobalt nanopillars by FEBID using diiron nonacarbonyl Fe2(CO)9, and dicobalt octacarbonyl Co2(CO)8, respectively, as starting materials. In addition, we systematically study the composition of these nanopillars at the sub-nanometer scale by atom probe tomography, explicitly mapping the homogeneity of the radial and longitudinal composition distributions. We show a way of fabricating high-purity 3D vertical nanostructures of ˜50 nm in diameter and a few micrometers in length. Our results suggest that the purity of such 3D nanoelements (above 90 at% Fe and above 95 at% Co) is directly linked to their growth regime, in which the selected deposition conditions are crucial for the final quality of the nanostructure. Moreover, we demonstrate that FEBID and the proposed characterization technique not only allow for growth and chemical analysis of single-element structures, but also offers a new way to directly study 3D core-shell architectures. This straightforward concept could establish a promising route to the design of 3D elements for future nano-electronic devices.

  4. High-purity 3D nano-objects grown by focused-electron-beam induced deposition

    Science.gov (United States)

    Córdoba, Rosa; Sharma, Nidhi; Kölling, Sebastian; Koenraad, Paul M.; Koopmans, Bert

    2016-09-01

    To increase the efficiency of current electronics, a specific challenge for the next generation of memory, sensing and logic devices is to find suitable strategies to move from two- to three-dimensional (3D) architectures. However, the creation of real 3D nano-objects is not trivial. Emerging non-conventional nanofabrication tools are required for this purpose. One attractive method is focused-electron-beam induced deposition (FEBID), a direct-write process of 3D nano-objects. Here, we grow 3D iron and cobalt nanopillars by FEBID using diiron nonacarbonyl Fe2(CO)9, and dicobalt octacarbonyl Co2(CO)8, respectively, as starting materials. In addition, we systematically study the composition of these nanopillars at the sub-nanometer scale by atom probe tomography, explicitly mapping the homogeneity of the radial and longitudinal composition distributions. We show a way of fabricating high-purity 3D vertical nanostructures of ∼50 nm in diameter and a few micrometers in length. Our results suggest that the purity of such 3D nanoelements (above 90 at% Fe and above 95 at% Co) is directly linked to their growth regime, in which the selected deposition conditions are crucial for the final quality of the nanostructure. Moreover, we demonstrate that FEBID and the proposed characterization technique not only allow for growth and chemical analysis of single-element structures, but also offers a new way to directly study 3D core–shell architectures. This straightforward concept could establish a promising route to the design of 3D elements for future nano-electronic devices.

  5. Efficient and high speed depth-based 2D to 3D video conversion

    Science.gov (United States)

    Somaiya, Amisha Himanshu; Kulkarni, Ramesh K.

    2013-09-01

    Stereoscopic video is the new era in video viewing and has wide applications such as medicine, satellite imaging and 3D Television. Such stereo content can be generated directly using S3D cameras. However, this approach requires expensive setup and hence converting monoscopic content to S3D becomes a viable approach. This paper proposes a depth-based algorithm for monoscopic to stereoscopic video conversion by using the y axis co-ordinates of the bottom-most pixels of foreground objects. This code can be used for arbitrary videos without prior database training. It does not face the limitations of single monocular depth cues nor does it combine depth cues, thus consuming less processing time without affecting the efficiency of the 3D video output. The algorithm, though not comparable to real-time, is faster than the other available 2D to 3D video conversion techniques in the average ratio of 1:8 to 1:20, essentially qualifying as high-speed. It is an automatic conversion scheme, hence directly gives the 3D video output without human intervention and with the above mentioned features becomes an ideal choice for efficient monoscopic to stereoscopic video conversion. [Figure not available: see fulltext.

  6. Design for High Performance, Low Power, and Reliable 3D Integrated Circuits

    CERN Document Server

    Lim, Sung Kyu

    2013-01-01

    This book describes the design of through-silicon-via (TSV) based three-dimensional integrated circuits.  It includes details of numerous “manufacturing-ready” GDSII-level layouts of TSV-based 3D ICs, developed with tools covered in the book. Readers will benefit from the sign-off level analysis of timing, power, signal integrity, and thermo-mechanical reliability for 3D IC designs.  Coverage also includes various design-for-manufacturability (DFM), design-for-reliability (DFR), and design-for-testability (DFT) techniques that are considered critical to the 3D IC design process. Describes design issues and solutions for high performance and low power 3D ICs, such as the pros/cons of regular and irregular placement of TSVs, Steiner routing, buffer insertion, low power 3D clock routing, power delivery network design and clock design for pre-bond testability. Discusses topics in design-for-electrical-reliability for 3D ICs, such as TSV-to-TSV coupling, current crowding at the wire-to-TSV junction and the e...

  7. Numerical 2D And 3D Simulations of a Spherical Fabry–Pérot Resonator for Application as a Reference Cavity for Laser Frequency Stabilisation

    Directory of Open Access Journals (Sweden)

    Nitiss E.

    2015-06-01

    Full Text Available We report on the results of a numerical study of deformations of a spherical Fabry-Pérot cavity that can be used for laser frequency stabilisation. It is demonstrated that for a precise simulation of the cavity deformations a 3D model has to be used instead of a simpler 2D model, which employs simulation on the symmetry plane of the cavity. To lower the sensitivity to environmental perturbations, it is suggested to use a material with a low density and a high Young’s modulus. We also show that the mechanical resonance frequencies of the cavity are mainly determined by the size of the cavity.

  8. Scalable, High-performance 3D Imaging Software Platform: System Architecture and Application to Virtual Colonoscopy

    OpenAIRE

    Yoshida, Hiroyuki; Wu, Yin; Cai, Wenli; Brett, Bevin

    2012-01-01

    One of the key challenges in three-dimensional (3D) medical imaging is to enable the fast turn-around time, which is often required for interactive or real-time response. This inevitably requires not only high computational power but also high memory bandwidth due to the massive amount of data that need to be processed. In this work, we have developed a software platform that is designed to support high-performance 3D medical image processing for a wide range of applications using increasingl...

  9. Composite 3D-printed metastructures for low-frequency and broadband vibration absorption

    Science.gov (United States)

    Matlack, Kathryn H.; Bauhofer, Anton; Krödel, Sebastian; Palermo, Antonio; Daraio, Chiara

    2016-07-01

    Architected materials that control elastic wave propagation are essential in vibration mitigation and sound attenuation. Phononic crystals and acoustic metamaterials use band-gap engineering to forbid certain frequencies from propagating through a material. However, existing solutions are limited in the low-frequency regimes and in their bandwidth of operation because they require impractical sizes and masses. Here, we present a class of materials (labeled elastic metastructures) that supports the formation of wide and low-frequency band gaps, while simultaneously reducing their global mass. To achieve these properties, the metastructures combine local resonances with structural modes of a periodic architected lattice. Whereas the band gaps in these metastructures are induced by Bragg scattering mechanisms, their key feature is that the band-gap size and frequency range can be controlled and broadened through local resonances, which are linked to changes in the lattice geometry. We demonstrate these principles experimentally, using advanced additive manufacturing methods, and inform our designs using finite-element simulations. This design strategy has a broad range of applications, including control of structural vibrations, noise, and shock mitigation.

  10. Composite 3D-printed metastructures for low-frequency and broadband vibration absorption.

    Science.gov (United States)

    Matlack, Kathryn H; Bauhofer, Anton; Krödel, Sebastian; Palermo, Antonio; Daraio, Chiara

    2016-07-26

    Architected materials that control elastic wave propagation are essential in vibration mitigation and sound attenuation. Phononic crystals and acoustic metamaterials use band-gap engineering to forbid certain frequencies from propagating through a material. However, existing solutions are limited in the low-frequency regimes and in their bandwidth of operation because they require impractical sizes and masses. Here, we present a class of materials (labeled elastic metastructures) that supports the formation of wide and low-frequency band gaps, while simultaneously reducing their global mass. To achieve these properties, the metastructures combine local resonances with structural modes of a periodic architected lattice. Whereas the band gaps in these metastructures are induced by Bragg scattering mechanisms, their key feature is that the band-gap size and frequency range can be controlled and broadened through local resonances, which are linked to changes in the lattice geometry. We demonstrate these principles experimentally, using advanced additive manufacturing methods, and inform our designs using finite-element simulations. This design strategy has a broad range of applications, including control of structural vibrations, noise, and shock mitigation. PMID:27410042

  11. 3D hierarchical porous graphene aerogels for highly improved adsorption and recycled capacity

    Energy Technology Data Exchange (ETDEWEB)

    Chi, Caixia [School of Chemical Engineering and Technology, Harbin Institute of Technology, Xida Zhi street 92, Harbin 150001 (China); Food and Pharmaceutical Engineering College, Suihua University, Suihua 152061 (China); Xu, Hongbo [School of Chemical Engineering and Technology, Harbin Institute of Technology, Xida Zhi street 92, Harbin 150001 (China); Zhang, Ke, E-mail: zhangke@hit.edu.cn [School of Chemical Engineering and Technology, Harbin Institute of Technology, Xida Zhi street 92, Harbin 150001 (China); Wang, Yibo [School of Chemical Engineering and Technology, Harbin Institute of Technology, Xida Zhi street 92, Harbin 150001 (China); Zhang, Shuanghu [Food and Pharmaceutical Engineering College, Suihua University, Suihua 152061 (China); Liu, Xusong; Liu, Xin; Zhao, Jiupeng [School of Chemical Engineering and Technology, Harbin Institute of Technology, Xida Zhi street 92, Harbin 150001 (China); Li, Yao, E-mail: yaoli@hit.edu.cn [Center for Composite Materials, Harbin Institute of Technology, Harbin 150001 (China)

    2015-04-15

    Graphical abstract: - Highlights: • 3D HGAs were prepared by a “fishing” process. • Their porous morphologies were varied by changing of PS particles. • HGAs are used as adsorbents for removal of oils and organic solvents. • They exhibit highly improved adsorption and recycled capacity. - Abstract: This article demonstrates the fabrication of 3D hierarchical porous graphene aerogels (HGAs) with tunable porous architecture by a “fishing” process with polystyrene (PS) particles as sacrificial templates. Structure and morphology were characterized by X-ray diffraction (XRD), Raman spectroscopy, and scanning electron microscopy (SEM), respectively. The 3D HGAs exhibits low density, super hydrophobicity, high porosity and good thermal stability, which were used as adsorbents for removal of oils and organic solvents, showing highly efficient adsorption. In addition, they could be regenerated by heat treatment to release the adsorbates. After eight toluene-adsorbing and drying recycles, the adsorption capacity of HGAs reaches 93% of the initial uptake.

  12. User-Appropriate Viewer for High Resolution Interactive Engagement with 3d Digital Cultural Artefacts

    Science.gov (United States)

    Gillespie, D.; La Pensée, A.; Cooper, M.

    2013-07-01

    Three dimensional (3D) laser scanning is an important documentation technique for cultural heritage. This technology has been adopted from the engineering and aeronautical industry and is an invaluable tool for the documentation of objects within museum collections (La Pensée, 2008). The datasets created via close range laser scanning are extremely accurate and the created 3D dataset allows for a more detailed analysis in comparison to other documentation technologies such as photography. The dataset can be used for a range of different applications including: documentation; archiving; surface monitoring; replication; gallery interactives; educational sessions; conservation and visualization. However, the novel nature of a 3D dataset is presenting a rather unique challenge with respect to its sharing and dissemination. This is in part due to the need for specialised 3D software and a supported graphics card to display high resolution 3D models. This can be detrimental to one of the main goals of cultural institutions, which is to share knowledge and enable activities such as research, education and entertainment. This has limited the presentation of 3D models of cultural heritage objects to mainly either images or videos. Yet with recent developments in computer graphics, increased internet speed and emerging technologies such as Adobe's Stage 3D (Adobe, 2013) and WebGL (Khronos, 2013), it is now possible to share a dataset directly within a webpage. This allows website visitors to interact with the 3D dataset allowing them to explore every angle of the object, gaining an insight into its shape and nature. This can be very important considering that it is difficult to offer the same level of understanding of the object through the use of traditional mediums such as photographs and videos. Yet this presents a range of problems: this is a very novel experience and very few people have engaged with 3D objects outside of 3D software packages or games. This paper

  13. Inversion of multi-frequency electromagnetic induction data for 3D characterization of hydraulic conductivity

    Science.gov (United States)

    Brosten, T.R.; Day-Lewis, F. D.; Schultz, G.M.; Curtis, G.P.; Lane, J.W.

    2011-01-01

    Electromagnetic induction (EMI) instruments provide rapid, noninvasive, and spatially dense data for characterization of soil and groundwater properties. Data from multi-frequency EMI tools can be inverted to provide quantitative electrical conductivity estimates as a function of depth. In this study, multi-frequency EMI data collected across an abandoned uranium mill site near Naturita, Colorado, USA, are inverted to produce vertical distribution of electrical conductivity (EC) across the site. The relation between measured apparent electrical conductivity (ECa) and hydraulic conductivity (K) is weak (correlation coefficient of 0.20), whereas the correlation between the depth dependent EC obtained from the inversions, and K is sufficiently strong to be used for hydrologic estimation (correlation coefficient of -0.62). Depth-specific EC values were correlated with co-located K measurements to develop a site-specific ln(EC)-ln(K) relation. This petrophysical relation was applied to produce a spatially detailed map of K across the study area. A synthetic example based on ECa values at the site was used to assess model resolution and correlation loss given variations in depth and/or measurement error. Results from synthetic modeling indicate that optimum correlation with K occurs at ~0.5m followed by a gradual correlation loss of 90% at 2.3m. These results are consistent with an analysis of depth of investigation (DOI) given the range of frequencies, transmitter-receiver separation, and measurement errors for the field data. DOIs were estimated at 2.0??0.5m depending on the soil conductivities. A 4-layer model, with varying thicknesses, was used to invert the ECa to maximize available information within the aquifer region for improved correlations with K. Results show improved correlation between K and the corresponding inverted EC at similar depths, underscoring the importance of inversion in using multi-frequency EMI data for hydrologic estimation. ?? 2011.

  14. High-performance 3D printing of hydrogels by water-dispersible photoinitiator nanoparticles

    Science.gov (United States)

    Pawar, Amol A.; Saada, Gabriel; Cooperstein, Ido; Larush, Liraz; Jackman, Joshua A.; Tabaei, Seyed R.; Cho, Nam-Joon; Magdassi, Shlomo

    2016-01-01

    In the absence of water-soluble photoinitiators with high absorbance in the ultraviolet (UV)–visible range, rapid three-dimensional (3D) printing of hydrogels for tissue engineering is challenging. A new approach enabling rapid 3D printing of hydrogels in aqueous solutions is presented on the basis of UV-curable inks containing nanoparticles of highly efficient but water-insoluble photoinitiators. The extinction coefficient of the new water-dispersible nanoparticles of 2,4,6-trimethylbenzoyl-diphenylphosphine oxide (TPO) is more than 300 times larger than the best and most used commercially available water-soluble photoinitiator. The TPO nanoparticles absorb significantly in the range from 385 to 420 nm, making them suitable for use in commercially available, low-cost, light-emitting diode–based 3D printers using digital light processing. The polymerization rate at this range is very fast and enables 3D printing that otherwise is impossible to perform without adding solvents. The TPO nanoparticles were prepared by rapid conversion of volatile microemulsions into water-dispersible powder, a process that can be used for a variety of photoinitiators. Such water-dispersible photoinitiator nanoparticles open many opportunities to enable rapid 3D printing of structures prepared in aqueous solutions while bringing environmental advantages by using low-energy curing systems and avoiding the need for solvents. PMID:27051877

  15. High-performance 3D printing of hydrogels by water-dispersible photoinitiator nanoparticles.

    Science.gov (United States)

    Pawar, Amol A; Saada, Gabriel; Cooperstein, Ido; Larush, Liraz; Jackman, Joshua A; Tabaei, Seyed R; Cho, Nam-Joon; Magdassi, Shlomo

    2016-04-01

    In the absence of water-soluble photoinitiators with high absorbance in the ultraviolet (UV)-visible range, rapid three-dimensional (3D) printing of hydrogels for tissue engineering is challenging. A new approach enabling rapid 3D printing of hydrogels in aqueous solutions is presented on the basis of UV-curable inks containing nanoparticles of highly efficient but water-insoluble photoinitiators. The extinction coefficient of the new water-dispersible nanoparticles of 2,4,6-trimethylbenzoyl-diphenylphosphine oxide (TPO) is more than 300 times larger than the best and most used commercially available water-soluble photoinitiator. The TPO nanoparticles absorb significantly in the range from 385 to 420 nm, making them suitable for use in commercially available, low-cost, light-emitting diode-based 3D printers using digital light processing. The polymerization rate at this range is very fast and enables 3D printing that otherwise is impossible to perform without adding solvents. The TPO nanoparticles were prepared by rapid conversion of volatile microemulsions into water-dispersible powder, a process that can be used for a variety of photoinitiators. Such water-dispersible photoinitiator nanoparticles open many opportunities to enable rapid 3D printing of structures prepared in aqueous solutions while bringing environmental advantages by using low-energy curing systems and avoiding the need for solvents. PMID:27051877

  16. High-performance 3D printing of hydrogels by water-dispersible photoinitiator nanoparticles.

    Science.gov (United States)

    Pawar, Amol A; Saada, Gabriel; Cooperstein, Ido; Larush, Liraz; Jackman, Joshua A; Tabaei, Seyed R; Cho, Nam-Joon; Magdassi, Shlomo

    2016-04-01

    In the absence of water-soluble photoinitiators with high absorbance in the ultraviolet (UV)-visible range, rapid three-dimensional (3D) printing of hydrogels for tissue engineering is challenging. A new approach enabling rapid 3D printing of hydrogels in aqueous solutions is presented on the basis of UV-curable inks containing nanoparticles of highly efficient but water-insoluble photoinitiators. The extinction coefficient of the new water-dispersible nanoparticles of 2,4,6-trimethylbenzoyl-diphenylphosphine oxide (TPO) is more than 300 times larger than the best and most used commercially available water-soluble photoinitiator. The TPO nanoparticles absorb significantly in the range from 385 to 420 nm, making them suitable for use in commercially available, low-cost, light-emitting diode-based 3D printers using digital light processing. The polymerization rate at this range is very fast and enables 3D printing that otherwise is impossible to perform without adding solvents. The TPO nanoparticles were prepared by rapid conversion of volatile microemulsions into water-dispersible powder, a process that can be used for a variety of photoinitiators. Such water-dispersible photoinitiator nanoparticles open many opportunities to enable rapid 3D printing of structures prepared in aqueous solutions while bringing environmental advantages by using low-energy curing systems and avoiding the need for solvents.

  17. High-resolution 3D ultrasound jawbone surface imaging for diagnosis of periodontal bony defects: an in vitro study.

    Science.gov (United States)

    Mahmoud, Ahmed M; Ngan, Peter; Crout, Richard; Mukdadi, Osama M

    2010-11-01

    Although medical specialties have recognized the importance of using ultrasonic imaging, dentistry is only beginning to discover its benefit. This has particularly been important in the field of periodontics which studies infections in the gum and bone tissues that surround the teeth. This study investigates the feasibility of using a custom-designed high-frequency ultrasound imaging system to reconstruct high-resolution (3D) surface images of periodontal defects in human jawbone. The system employs single-element focused ultrasound transducers with center frequencies ranging from 30 to 60 MHz. Continuous acquisition using a 1 GHz data acquisition card is synchronized with a high-precision two-dimensional (2D) positioning system of ±1 μm resolution for acquiring accurate measurements of the mandible, in vitro. Signal and image processing algorithms are applied to reconstruct high-resolution ultrasound images and extract the jawbone surface in each frame. Then, all edges are combined and smoothed in order to render a 3D surface image of the jawbone. In vitro experiments were performed to assess the system performance using mandibles with teeth (dentate) or without (nondentate). The system was able to reconstruct 3D images for the mandible's outer surface with superior spatial resolution down to 24 μm, and to perform the whole scanning in images were confirmed with the anatomical structures on the mandibles. All the anatomical landmarks were detected and fully described as 3D images using this novel ultrasound imaging technique, whereas the 2D X-ray radiographic images suffered from poor contrast. These results indicate the great potential of utilizing high-resolution ultrasound as a noninvasive, nonionizing imaging technique for the early diagnosis of the more severe form of periodontal disease.

  18. Development of a High Resolution 3D Infant Stomach Model for Surgical Planning

    Science.gov (United States)

    Chaudry, Qaiser; Raza, S. Hussain; Lee, Jeonggyu; Xu, Yan; Wulkan, Mark; Wang, May D.

    Medical surgical procedures have not changed much during the past century due to the lack of accurate low-cost workbench for testing any new improvement. The increasingly cheaper and powerful computer technologies have made computer-based surgery planning and training feasible. In our work, we have developed an accurate 3D stomach model, which aims to improve the surgical procedure that treats the infant pediatric and neonatal gastro-esophageal reflux disease (GERD). We generate the 3-D infant stomach model based on in vivo computer tomography (CT) scans of an infant. CT is a widely used clinical imaging modality that is cheap, but with low spatial resolution. To improve the model accuracy, we use the high resolution Visible Human Project (VHP) in model building. Next, we add soft muscle material properties to make the 3D model deformable. Then we use virtual reality techniques such as haptic devices to make the 3D stomach model deform upon touching force. This accurate 3D stomach model provides a workbench for testing new GERD treatment surgical procedures. It has the potential to reduce or eliminate the extensive cost associated with animal testing when improving any surgical procedure, and ultimately, to reduce the risk associated with infant GERD surgery.

  19. 3D High Resolution l1-SPIRiT Reconstruction on Gadgetron based Cloud

    DEFF Research Database (Denmark)

    Xue, Hui; Kelmann, Peter; Inati, Souheil;

    framework to support distributed computing in a cloud environment. This extension is named GT-Plus. A cloud version of 3D l1-SPIRiT was implemented on the GT-Plus framework. We demonstrate that a 3mins reconstruction could be achieved for 1mm3 isotropic resolution neuro scans with significantly improved......Applying non-linear reconstruction to high resolution 3D MRI is challenging because of the lengthy computing time needed for those iterative algorithms. To achieve practical processing duration to enable clinical usage of non-linear reconstruction, we have extended previously published Gadgetron...

  20. Minimally Invasive Cardiac Surgery Using a 3D High-Definition Endoscopic System.

    Science.gov (United States)

    Ruttkay, Tamas; Götte, Julia; Walle, Ulrike; Doll, Nicolas

    2015-01-01

    We describe a minimally invasive heart surgery application of the EinsteinVision 2.0 3D high-definition endoscopic system (Aesculap AG, Tuttlingen, Germany) in an 81-year-old man with severe tricuspid valve insufficiency. Fourteen years ago, he underwent a Ross procedure followed by a DDD pacemaker implantation 4 years later for tachy-brady-syndrome. His biventricular function was normal. We recommended minimally invasive tricuspid valve repair. The application of the aformentioned endoscopic system was simple, and the impressive 3D depth view offered an easy and precise manipulation through a minimal thoracotomy incision, avoiding the need for a rib spreading retractor.

  1. 2D and 3D CMOS MAPS with high performance pixel-level signal processing

    Energy Technology Data Exchange (ETDEWEB)

    Traversi, Gianluca, E-mail: gianluca.traversi@unibg.i [University of Bergamo and INFN Pavia, Via Marconi 5, Dalmine 24044 (Italy); Gaioni, Luigi; Manghisoni, Massimo [University of Bergamo and INFN Pavia, Via Marconi 5, Dalmine 24044 (Italy); Ratti, Lodovico [University of Pavia and INFN Pavia (Italy); Re, Valerio [University of Bergamo and INFN Pavia, Via Marconi 5, Dalmine 24044 (Italy)

    2011-02-01

    Deep N-well (DNW) MAPS have been developed in the last few years with the aim of building monolithic sensors with similar functionalities as hybrid pixels systems. These devices have been fabricated in a planar (2D) 130 nm CMOS technology. The triple-well structure available in such an ultra-deep submicron technology is exploited by using the deep N-well as the charge-collecting electrode. This paper intends to discuss the design features and measurement results of the last prototype (Apsel5T chip) recently fabricated in a 2D 130 nm CMOS technology. Recent advances in microelectronics industry have made 3D integrated circuits an option for High Energy Physics experiments. A 3D version of the Apsel5T chip has been designed in a 130 nm CMOS, two-layer, vertically integrated technology. The main features of this new 3D monolithic detector are presented in this paper.

  2. The new high resolution method of Godunov`s type for 3D viscous flow calculations

    Energy Technology Data Exchange (ETDEWEB)

    Yershov, S.V.; Rusanov, A.V. [Ukranian National Academy of Sciences, Kahrkov (Ukraine)

    1996-12-31

    The numerical method is suggested for the calculations of the 3D viscous compressible flows described by the thin-layer Reynolds-averaged Navier-Stokes equations. The method is based on the Godunov`s finite-difference scheme and it uses the ENO reconstruction suggested by Harten to achieve the uniformly high-order accuracy. The computational efficiency is provided with the simplified multi grid approach and the implicit step written in {delta} -form. The turbulent effects are simulated with the Baldwin - Lomax turbulence model. The application package FlowER is developed to calculate the 3D turbulent flows within complex-shape channels. The numerical results for the 3D flow around a cylinder and through the complex-shaped channels show the accuracy and the reliability of the suggested method. (author)

  3. 3-D Rat Brain Phantom for High-Resolution Molecular Imaging

    NARCIS (Netherlands)

    F.J. Beekman; B. Vastenhouw; G. van der Wilt; M. Vervloet; R. Visscher; J. Booij; M. Gerrits; C. Ji; R. Ramakers; F. van der Have

    2009-01-01

    With the steadily improving resolution of novel small-animal single photon emission computed tomography (SPECT) and positron emission tomography devices, highly detailed phantoms are required for testing and optimizing these systems. We present a three-dimensional (3-D) digital and physical phantom

  4. Unidirectional high fiber content composites: Automatic 3D FE model generation and damage simulation

    DEFF Research Database (Denmark)

    Qing, Hai; Mishnaevsky, Leon

    2009-01-01

    A new method and a software code for the automatic generation of 3D micromechanical FE models of unidirectional long-fiber-reinforced composite (LFRC) with high fiber volume fraction with random fiber arrangement are presented. The fiber arrangement in the cross-section is generated through random...

  5. High-order finite difference solution for 3D nonlinear wave-structure interaction

    DEFF Research Database (Denmark)

    Ducrozet, Guillaume; Bingham, Harry B.; Engsig-Karup, Allan Peter;

    2010-01-01

    This contribution presents our recent progress on developing an efficient fully-nonlinear potential flow model for simulating 3D wave-wave and wave-structure interaction over arbitrary depths (i.e. in coastal and offshore environment). The model is based on a high-order finite difference scheme...

  6. Frequency of infraossal aproximal bone defects in maxilla and mandibulla, found with 3D cone beam volumetric tomography

    International Nuclear Information System (INIS)

    Periodontal disease is characterized with two types of bone resorption: horizontal and vertical. The latter is responsible for formation of intraossal bone defects (ID). These defects are treated by regenerative periodontal therapy. The 'golden standard' for their diagnosis is a full set of intraoral radiographs, followed by ortopantomographic (OPG) images. With the introduction of 3D cone beam volumetric tomography (CVT) method, which is highly sensitive, many limitations of 2D images are overwhelmed. The aim of the study was to the ability of 3D VCT to discover ID in comparison with 2D OPG; 2) To describe the ID by: sex, age. number of teeth, tooth number, degree of alveolar bone resorption, depth of ID, width of ID, angle of ID, Tooth condition with ID The study used 121 patients who had visited FDM - Plovdiv. 47,1% were man and 52,9% women. Their age was form 11 to 99 years. 2698 were evaluated. We accepted ID with depth (INFRA) >3mm. Images were acquired with Galileos (Sirona). First were studied the 2D images for ID and then again with the help of 3D CVT after which the parameters of the ID were recorded. With 2D and 3D were found correspondingly: ID in 20 (16,5%) and 49 (40.5%) patients; 45 (1.66%) and 113 (4.18%) in teeth, with statistical significance (p<0.0001). ID were mainly prevalent in lower jaw (62.8%), and in molars 47,37,36 (26.5%). We found statistically significant more ID with the increase of age and degree of alveolar bone resorption. 3D CVT is significantly more sensitive than 2D OPG. It is advisable that this method is used more frequently in periodontology for diagnosis and evaluation of treatment effect

  7. 3D high spectral and spatial resolution imaging of ex vivo mouse brain

    Energy Technology Data Exchange (ETDEWEB)

    Foxley, Sean, E-mail: sean.foxley@ndcn.ox.ac.uk; Karczmar, Gregory S. [Department of Radiology, University of Chicago, Chicago, Illinois 60637 (United States); Domowicz, Miriam [Department of Pediatrics, University of Chicago, Chicago, Illinois 60637 (United States); Schwartz, Nancy [Department of Pediatrics, Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637 (United States)

    2015-03-15

    Purpose: Widely used MRI methods show brain morphology both in vivo and ex vivo at very high resolution. Many of these methods (e.g., T{sub 2}{sup *}-weighted imaging, phase-sensitive imaging, or susceptibility-weighted imaging) are sensitive to local magnetic susceptibility gradients produced by subtle variations in tissue composition. However, the spectral resolution of commonly used methods is limited to maintain reasonable run-time combined with very high spatial resolution. Here, the authors report on data acquisition at increased spectral resolution, with 3-dimensional high spectral and spatial resolution MRI, in order to analyze subtle variations in water proton resonance frequency and lineshape that reflect local anatomy. The resulting information compliments previous studies based on T{sub 2}{sup *} and resonance frequency. Methods: The proton free induction decay was sampled at high resolution and Fourier transformed to produce a high-resolution water spectrum for each image voxel in a 3D volume. Data were acquired using a multigradient echo pulse sequence (i.e., echo-planar spectroscopic imaging) with a spatial resolution of 50 × 50 × 70 μm{sup 3} and spectral resolution of 3.5 Hz. Data were analyzed in the spectral domain, and images were produced from the various Fourier components of the water resonance. This allowed precise measurement of local variations in water resonance frequency and lineshape, at the expense of significantly increased run time (16–24 h). Results: High contrast T{sub 2}{sup *}-weighted images were produced from the peak of the water resonance (peak height image), revealing a high degree of anatomical detail, specifically in the hippocampus and cerebellum. In images produced from Fourier components of the water resonance at −7.0 Hz from the peak, the contrast between deep white matter tracts and the surrounding tissue is the reverse of the contrast in water peak height images. This indicates the presence of a shoulder in

  8. 3D MODELLING OF PROPHYLACTIC FOOTWEAR FOR A HIGH ARCHED FOOT

    Directory of Open Access Journals (Sweden)

    COSTEA Mariana

    2016-05-01

    Full Text Available This article approaches the methodology of designing customized footwear for high arched foot. The authors propose to reconsider the classical structure of footwear bottom components for people with high arched foot and recommend incorporating custom components, with the role of compensation or adjustment. This study continues the authors’ research, starting from a foot’s 3D shape obtained by 3D scanning, the anthropometrical and biomechanical parameters, shoe lasts’ 3D modelling and continuing with 3D footwear design. Including customized orthosis can help to stop the evolution of abnormalities, diminishes sensations of pain during walking and improves performance in various physical activities carried out during the day, walking, running, and standing. The prophylactic footwear has to meet four main requirements: to protect the foot and ankle during walking and static; to ensure the normal resistance systems (bones, muscle and joint of the foot; to prevent the installation of irreversible structural changes by reducing stress on the foot; to contribute to increased performance in conducting regular physical activity. It is presented the steps of modelling an orthosis, a virtual simulation of its cutting process, followed by the integration and development of the insole, filling and sole for a customized shoe. Delcam Crispin CAD system and its applications for orthopaedics are used to design the bottom components of prophylactic footwear for a high arched foot.

  9. High sensitivity plasmonic biosensor based on nanoimprinted quasi 3D nanosquares for cell detection

    Science.gov (United States)

    Zhu, Shuyan; Li, Hualin; Yang, Mengsu; Pang, Stella W.

    2016-07-01

    Quasi three-dimensional (3D) plasmonic nanostructures consisting of Au nanosquares on top of SU-8 nanopillars and Au nanoholes on the bottom were developed and fabricated using nanoimprint lithography with simultaneous thermal and UV exposure. These 3D plasmonic nanostructures were used to detect cell concentration of lung cancer A549 cells, retinal pigment epithelial (RPE) cells, and breast cancer MCF-7 cells. Nanoimprint technology has the advantage of producing high uniformity plasmonic nanostructures for such biosensors. Multiple resonance modes were observed in these quasi 3D plasmonic nanostructures. The hybrid coupling of localized surface plasmon resonances and Fabry-Perot cavity modes in the quasi 3D nanostructures resulted in high sensitivity of 496 nm/refractive index unit. The plasmonic resonance peak wavelength and sensitivity could be tuned by varying the Au thickness. Resonance peak shifts for different cells at the same concentration were distinct due to their different cell area and confluency. The cell concentration detection limit covered a large range of 5 × 102 to 1 × 107 cells ml-1 with these new plasmonic nanostructures. They also provide a large resonance peak shift of 51 nm for as little as 0.08 cells mm-2 of RPE cells for high sensitivity cell detection.

  10. IGUANA A high-performance 2D and 3D visualisation system

    CERN Document Server

    Alverson, G; Muzaffar, S; Osborne, I; Taylor, L; Tuura, L A

    2004-01-01

    The IGUANA project has developed visualisation tools for multiple high-energy experiments. At the core of IGUANA is a generic, high- performance visualisation system based on OpenInventor and OpenGL. This paper describes the back-end and a feature-rich 3D visualisation system built on it, as well as a new 2D visualisation system that can automatically generate 2D views from 3D data, for example to produce R/Z or X/Y detector displays from existing 3D display with little effort. IGUANA has collaborated with the open-source gl2ps project to create a high-quality vector postscript output that can produce true vector graphics output from any OpenGL 2D or 3D display, complete with surface shading and culling of invisible surfaces. We describe how it works. We also describe how one can measure the memory and performance costs of various OpenInventor constructs and how to test scene graphs. We present good patterns to follow and bad patterns to avoid. We have added more advanced tools such as per-object clipping, sl...

  11. GIS Data Based Automatic High-Fidelity 3D Road Network Modeling

    Science.gov (United States)

    Wang, Jie; Shen, Yuzhong

    2011-01-01

    3D road models are widely used in many computer applications such as racing games and driving simulations_ However, almost all high-fidelity 3D road models were generated manually by professional artists at the expense of intensive labor. There are very few existing methods for automatically generating 3D high-fidelity road networks, especially those existing in the real world. This paper presents a novel approach thai can automatically produce 3D high-fidelity road network models from real 2D road GIS data that mainly contain road. centerline in formation. The proposed method first builds parametric representations of the road centerlines through segmentation and fitting . A basic set of civil engineering rules (e.g., cross slope, superelevation, grade) for road design are then selected in order to generate realistic road surfaces in compliance with these rules. While the proposed method applies to any types of roads, this paper mainly addresses automatic generation of complex traffic interchanges and intersections which are the most sophisticated elements in the road networks

  12. Dubai 3d Textuerd Mesh Using High Quality Resolution Vertical/oblique Aerial Imagery

    Science.gov (United States)

    Tayeb Madani, Adib; Ziad Ahmad, Abdullateef; Christoph, Lueken; Hammadi, Zamzam; Manal Abdullah Sabeal, Manal Abdullah x.

    2016-06-01

    Providing high quality 3D data with reasonable quality and cost were always essential, affording the core data and foundation for developing an information-based decision-making tool of urban environments with the capability of providing decision makers, stakeholders, professionals, and public users with 3D views and 3D analysis tools of spatial information that enables real-world views. Helps and assist in improving users' orientation and also increase their efficiency in performing their tasks related to city planning, Inspection, infrastructures, roads, and cadastre management. In this paper, the capability of multi-view Vexcel UltraCam Osprey camera images is examined to provide a 3D model of building façades using an efficient image-based modeling workflow adopted by commercial software's. The main steps of this work include: Specification, point cloud generation, and 3D modeling. After improving the initial values of interior and exterior parameters at first step, an efficient image matching technique such as Semi Global Matching (SGM) is applied on the images to generate point cloud. Then, a mesh model of points is calculated using and refined to obtain an accurate model of buildings. Finally, a texture is assigned to mesh in order to create a realistic 3D model. The resulting model has provided enough LoD2 details of the building based on visual assessment. The objective of this paper is neither comparing nor promoting a specific technique over the other and does not mean to promote a sensor-based system over another systems or mechanism presented in existing or previous paper. The idea is to share experience.

  13. DUBAI 3D TEXTUERD MESH USING HIGH QUALITY RESOLUTION VERTICAL/OBLIQUE AERIAL IMAGERY

    Directory of Open Access Journals (Sweden)

    A. T. Madani

    2016-06-01

    Full Text Available Providing high quality 3D data with reasonable quality and cost were always essential, affording the core data and foundation for developing an information-based decision-making tool of urban environments with the capability of providing decision makers, stakeholders, professionals, and public users with 3D views and 3D analysis tools of spatial information that enables real-world views. Helps and assist in improving users’ orientation and also increase their efficiency in performing their tasks related to city planning, Inspection, infrastructures, roads, and cadastre management. In this paper, the capability of multi-view Vexcel UltraCam Osprey camera images is examined to provide a 3D model of building façades using an efficient image-based modeling workflow adopted by commercial software’s. The main steps of this work include: Specification, point cloud generation, and 3D modeling. After improving the initial values of interior and exterior parameters at first step, an efficient image matching technique such as Semi Global Matching (SGM is applied on the images to generate point cloud. Then, a mesh model of points is calculated using and refined to obtain an accurate model of buildings. Finally, a texture is assigned to mesh in order to create a realistic 3D model. The resulting model has provided enough LoD2 details of the building based on visual assessment. The objective of this paper is neither comparing nor promoting a specific technique over the other and does not mean to promote a sensor-based system over another systems or mechanism presented in existing or previous paper. The idea is to share experience.

  14. High fidelity digital inline holographic method for 3D flow measurements.

    Science.gov (United States)

    Toloui, Mostafa; Hong, Jiarong

    2015-10-19

    Among all the 3D optical flow diagnostic techniques, digital inline holographic particle tracking velocimetry (DIH-PTV) provides the highest spatial resolution with low cost, simple and compact optical setups. Despite these advantages, DIH-PTV suffers from major limitations including poor longitudinal resolution, human intervention (i.e. requirement for manually determined tuning parameters during tracer field reconstruction and extraction), limited tracer concentration, and expensive computations. These limitations prevent this technique from being widely used for high resolution 3D flow measurements. In this study, we present a novel holographic particle extraction method with the goal of overcoming all the major limitations of DIH-PTV. The proposed method consists of multiple steps involving 3D deconvolution, automatic signal-to-noise ratio enhancement and thresholding, and inverse iterative particle extraction. The entire method is implemented using GPU-based algorithm to increase the computational speed significantly. Validated with synthetic particle holograms, the proposed method can achieve particle extraction rate above 95% with fake particles less than 3% and maximum position error below 1.6 particle diameter for holograms with particle concentration above 3000 particles/mm3. The applicability of the proposed method for DIH-PTV has been further validated using the experiment of laminar flow in a microchannel and the synthetic tracer flow fields generated using a DNS turbulent channel flow database. Such improvements will substantially enhance the implementation of DIH-PTV for 3D flow measurements and enable the potential commercialization of this technique. PMID:26480377

  15. Development of a version of the reactor dynamics code DYN3D applicable for High Temperature Reactors; Entwicklung einer Version des Reaktordynamikcodes DYN3D fuer Hochtemperaturreaktoren. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Rohde, Ulrich; Apanasevich, Pavel; Baier, Silvio; Duerigen, Susan; Fridman, Emil; Grahn, Alexander; Kliem, Soeren; Merk, Bruno

    2012-07-15

    Based on the reactor dynamics code DYN3D for the simulation of transient processes in Light Water Reactors, a code version DYN3D-HTR for application to graphitemoderated, gas-cooled block-type high temperature reactors has been developed. This development comprises: - the methodical improvement of the 3D steady-state neutron flux calculation for the hexagonal geometry of the HTR fuel element blocks - the development of methods for the generation of homogenised cross section data taking into account the double heterogeneity of the fuel element block structure - the implementation of a 3D model for heat conduction and heat transport in the graphite matrix. The nodal method for neutron flux calculation based on SP3 transport approximation was extended to hexagonal fuel element geometry, where the hexagons are subdivided into triangles, thus the method had finally to be derived for triangular geometry. In triangular geometry, a subsequent subdivision of the hexagonal elements can be considered, and therefore, the effect of systematic mesh refinement can be studied. The algorithm was verified by comparison with Monte Carlo reference solutions, on the node-wise level, as well as also on the pin-wise level. New procedures were developed for the homogenization of the double-heterogeneous fuel element structures. One the one hand, the so-called Reactivity equivalent Physical Transformation (RPT), the two-step homogenization method based on 2D deterministic lattice calculations, was extended to cells with different temperatures of the materials. On the other hand, the progress in development of Monte Carlo methods for spectral calculations, in particular the development of the code SERPENT, opened a new, fully consistent 3D approach, where all details of the structures on fuel particle, fuel compact and fuel block level can be taken into account within one step. Moreover, a 3D heat conduction and heat transport model was integrated into DYN3D to be able to simulate radial

  16. Assessment of dose-volume histograms in brachytherapy 3D high-rate; Evaluacion de los histogramas dosis volumen en braquiterapia de alta tasa 3D

    Energy Technology Data Exchange (ETDEWEB)

    Gomez Barrado, A.; Tripero Oter, J.; Sanchez Jimenez, E.; Sanchez-Reyes, A.

    2013-07-01

    The use of systems of treatment planning using 3D reconstruction algorithms are becoming more frequent in brachytherapy treatments. The implementation of these systems entails great qualitative and quantitative procedural changes in the way to evaluate the clinical dosimetry about the 2D classical systems. This paper describes the experience of our Centre in employment and prescription dose using histograms dose-volume in the treatment of brachytherapy of high rate. (Author)

  17. High sensitivity and high resolution element 3D analysis by a combined SIMS–SPM instrument

    Directory of Open Access Journals (Sweden)

    Yves Fleming

    2015-04-01

    Full Text Available Using the recently developed SIMS–SPM prototype, secondary ion mass spectrometry (SIMS data was combined with topographical data from the scanning probe microscopy (SPM module for five test structures in order to obtain accurate chemical 3D maps: a polystyrene/polyvinylpyrrolidone (PS/PVP polymer blend, a nickel-based super-alloy, a titanium carbonitride-based cermet, a reticle test structure and Mg(OH2 nanoclusters incorporated inside a polymer matrix. The examples illustrate the potential of this combined approach to track and eliminate artefacts related to inhomogeneities of the sputter rates (caused by samples containing various materials, different phases or having a non-flat surface and inhomogeneities of the secondary ion extraction efficiencies due to local field distortions (caused by topography with high aspect ratios. In this respect, this paper presents the measured relative sputter rates between PVP and PS as well as in between the different phases of the TiCN cermet.

  18. The extent of the Cratonic keel underneath the Southern African region: A 3D image using Finite-Frequency Tomograph

    DEFF Research Database (Denmark)

    Soliman, Mohammad Youssof Ahmad; Bezada, Max; Thybo, Hans;

    2010-01-01

    We have re-examined the P body wave data from the South Africa Seismic Experiment (Carlson et al, EOS 77, 1996) across the Kaapvaal and Zimbabwe cratons and the Bushveld complex. Using finite-frequency kernels, we inverted the P-wave delay times to obtain 3-D images of compressional velocity....... We also image significant positive and negative anomalies (±3.0%) unconnected to the cratons under the cratonic keels and in the transition zone. We are currently inverting the P wave data using different reference models, and examining the S-wave travel times....... parameter in the deeper layers progressively and examined the rms misfit and the imaged structure. Visual inspection of the tomographic images produced from these inversions showed that the lateral distribution of structures remained unchanged as the depth of the model was reduced and deep structures...

  19. Towards high resolution mapping of 3-D mesoscale dynamics from observations

    Directory of Open Access Journals (Sweden)

    B. Buongiorno Nardelli

    2012-10-01

    Full Text Available The MyOcean R&D project MESCLA (MEsoSCaLe dynamical Analysis through combined model, satellite and in situ data was devoted to the high resolution 3-D retrieval of tracer and velocity fields in the oceans, based on the combination of in situ and satellite observations and quasi-geostrophic dynamical models. The retrieval techniques were also tested and compared with the output of a primitive equation model, with particular attention to the accuracy of the vertical velocity field as estimated through the Q vector formulation of the omega equation. The project focused on a test case, covering the region where the Gulf Stream separates from the US East Coast. This work demonstrated that innovative methods for the high resolution mapping of 3-D mesoscale dynamics from observations can be used to build the next generations of operational observation-based products.

  20. Identifying High Potential Well Targets with 3D Seismic and Mineralogy

    Energy Technology Data Exchange (ETDEWEB)

    Mellors, R. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-30

    Seismic reflection the primary tool used in petroleum exploration and production, but use in geothermal exploration is less standard, in part due to cost but also due to the challenges in identifying the highly-permeable zones essential for economic hydrothermal systems [e.g. Louie et al., 2011; Majer, 2003]. Newer technology, such as wireless sensors and low-cost high performance computing, has helped reduce the cost and effort needed to conduct 3D surveys. The second difficulty, identifying permeable zones, has been less tractable so far. Here we report on the use of seismic attributes from a 3D seismic survey to identify and map permeable zones in a hydrothermal area.

  1. 3D silicon sensors with variable electrode depth for radiation hard high resolution particle tracking

    International Nuclear Information System (INIS)

    3D sensors, with electrodes micro-processed inside the silicon bulk using Micro-Electro-Mechanical System (MEMS) technology, were industrialized in 2012 and were installed in the first detector upgrade at the LHC, the ATLAS IBL in 2014. They are the radiation hardest sensors ever made. A new idea is now being explored to enhance the three-dimensional nature of 3D sensors by processing collecting electrodes at different depths inside the silicon bulk. This technique uses the electric field strength to suppress the charge collection effectiveness of the regions outside the p-n electrodes' overlap. Evidence of this property is supported by test beam data of irradiated and non-irradiated devices bump-bonded with pixel readout electronics and simulations. Applications include High-Luminosity Tracking in the high multiplicity LHC forward regions. This paper will describe the technical advantages of this idea and the tracking application rationale

  2. A high-throughput in vitro ring assay for vasoactivity using magnetic 3D bioprinting.

    Science.gov (United States)

    Tseng, Hubert; Gage, Jacob A; Haisler, William L; Neeley, Shane K; Shen, Tsaiwei; Hebel, Chris; Barthlow, Herbert G; Wagoner, Matthew; Souza, Glauco R

    2016-01-01

    Vasoactive liabilities are typically assayed using wire myography, which is limited by its high cost and low throughput. To meet the demand for higher throughput in vitro alternatives, this study introduces a magnetic 3D bioprinting-based vasoactivity assay. The principle behind this assay is the magnetic printing of vascular smooth muscle cells into 3D rings that functionally represent blood vessel segments, whose contraction can be altered by vasodilators and vasoconstrictors. A cost-effective imaging modality employing a mobile device is used to capture contraction with high throughput. The goal of this study was to validate ring contraction as a measure of vasoactivity, using a small panel of known vasoactive drugs. In vitro responses of the rings matched outcomes predicted by in vivo pharmacology, and were supported by immunohistochemistry. Altogether, this ring assay robustly models vasoactivity, which could meet the need for higher throughput in vitro alternatives. PMID:27477945

  3. P-Cable: New High-Resolution 3D Seismic Acquisition Technology

    Science.gov (United States)

    Planke, Sverre; Berndt, Christian; Mienert, Jürgen; Bünz, Stefan; Eriksen, Frode N.; Eriksen, Ola K.

    2010-05-01

    We have developed a new cost-efficient technology for acquisition of high-resolution 3D seismic data: the P-Cable system. This technology is very well suited for deep water exploration, site surveys, and studies of shallow gas and fluid migration associated with gas hydrates or leaking reservoirs. It delivers unparalleled 3D seismic images of subsurface sediment architectures. The P-Cable system consists of a seismic cable towed perpendicular to a vessel's steaming direction. This configuration allows us to image an up to 150 m wide swath of the sub-surface for each sail line. Conventional 3D seismic technology relies on several very long streamers (up to 10 km long streamers are common), large sources, and costly operations. In contrast, the P-Cable system is light-weight and fast to deploy from small vessels. Only a small source is required as the system is made for relatively shallow imaging, typically above the first water-bottom multiple. The P-Cable system is particularly useful for acquisition of small 3D cubes, 10-50 km2, in focus areas, rather than extensive mapping of large regions. The rapid deployment and recovery of the system makes it possible to acquire several small cubes (10 to 30 km2) with high-resolution (50-250 Hz) seismic data in during one cruise. The first development of the P-Cable system was a cooperative project achieved by Volcanic Basin Petroleum Research (VBPR), University of Tromsø, National Oceanography Centre, Southampton, and industry partners. Field trials using a 12-streamer system were conducted on sites with active fluid-leakage systems on the Norwegian-Barents-Svalbard margin, the Gulf of Cadiz, and the Mediterranean. The second phase of the development introduced digital streamers. The new P-Cable2 system also includes integrated tow and cross cables for power and data transmission and improved doors to spread the larger cross cable. This digital system has been successfully used during six cruises by the University of Troms

  4. Microwave Radiometer - high frequency

    Data.gov (United States)

    Oak Ridge National Laboratory — The Microwave Radiometer-High Frequency (MWRHF) provides time-series measurements of brightness temperatures from two channels centered at 90 and 150 GHz. These two...

  5. Markerless 3D Head Tracking for Motion Correction in High Resolution PET Brain Imaging

    DEFF Research Database (Denmark)

    Olesen, Oline Vinter

    This thesis concerns application specific 3D head tracking. The purpose is to improve motion correction in position emission tomography (PET) brain imaging through development of markerless tracking. Currently, motion correction strategies are based on either the PET data itself or tracking devices...... images. Incorrect motion correction can in the worst cases result in wrong diagnosis or treatment. The evolution of a markerless custom-made structured light 3D surface tracking system is presented. The system is targeted at state-of-the-art high resolution dedicated brain PET scanners with a resolution...... of a few millimeters. Stateof- the-art hardware and software solutions are integrated into an operational device. This novel system is tested against a commercial tracking system popular in PET brain imaging. Testing and demonstrations are carried out in clinical settings. A compact markerless tracking...

  6. General 3D Lumped Thermal Model with Various Boundary Conditions for High Power IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2016-01-01

    Accurate thermal dynamics modeling of high power Insulated Gate Bipolar Transistor (IGBT) modules is important information for the reliability analysis and thermal design of power electronic systems. However, the existing thermal models have their limits to correctly predict these complicated...... thermal behaviors in the IGBTs. In this paper, a new three-dimensional (3D) lumped thermal model is proposed, which can easily be characterized from Finite Element Methods (FEM) based simulation and acquire the thermal distribution in critical points. Meanwhile the boundary conditions including...... the cooling system and power losses are modeled in the 3D thermal model, which can be adapted to different real field applications of power electronic converters. The accuracy of the proposed thermal model is verified by experimental results....

  7. A highly heterogeneous 3D PWR core benchmark: deterministic and Monte Carlo method comparison

    Science.gov (United States)

    Jaboulay, J.-C.; Damian, F.; Douce, S.; Lopez, F.; Guenaut, C.; Aggery, A.; Poinot-Salanon, C.

    2014-06-01

    Physical analyses of the LWR potential performances with regards to the fuel utilization require an important part of the work dedicated to the validation of the deterministic models used for theses analyses. Advances in both codes and computer technology give the opportunity to perform the validation of these models on complex 3D core configurations closed to the physical situations encountered (both steady-state and transient configurations). In this paper, we used the Monte Carlo Transport code TRIPOLI-4®; to describe a whole 3D large-scale and highly-heterogeneous LWR core. The aim of this study is to validate the deterministic CRONOS2 code to Monte Carlo code TRIPOLI-4®; in a relevant PWR core configuration. As a consequence, a 3D pin by pin model with a consistent number of volumes (4.3 millions) and media (around 23,000) is established to precisely characterize the core at equilibrium cycle, namely using a refined burn-up and moderator density maps. The configuration selected for this analysis is a very heterogeneous PWR high conversion core with fissile (MOX fuel) and fertile zones (depleted uranium). Furthermore, a tight pitch lattice is selcted (to increase conversion of 238U in 239Pu) that leads to harder neutron spectrum compared to standard PWR assembly. In these conditions two main subjects will be discussed: the Monte Carlo variance calculation and the assessment of the diffusion operator with two energy groups for the core calculation.

  8. Highly Concentrated Alginate-Gellan Gum Composites for 3D Plotting of Complex Tissue Engineering Scaffolds

    Directory of Open Access Journals (Sweden)

    Ashwini Rahul Akkineni

    2016-04-01

    Full Text Available In tissue engineering, additive manufacturing (AM technologies have brought considerable progress as they allow the fabrication of three-dimensional (3D structures with defined architecture. 3D plotting is a versatile, extrusion-based AM technology suitable for processing a wide range of biomaterials including hydrogels. In this study, composites of highly concentrated alginate and gellan gum were prepared in order to combine the excellent printing properties of alginate with the favorable gelling characteristics of gellan gum. Mixtures of 16.7 wt % alginate and 2 or 3 wt % gellan gum were found applicable for 3D plotting. Characterization of the resulting composite scaffolds revealed an increased stiffness in the wet state (15%–20% higher Young’s modulus and significantly lower volume swelling in cell culture medium compared to pure alginate scaffolds (~10% vs. ~23%. Cytocompatibility experiments with human mesenchymal stem cells (hMSC revealed that cell attachment was improved—the seeding efficiency was ~2.5–3.5 times higher on the composites than on pure alginate. Additionally, the composites were shown to support hMSC proliferation and early osteogenic differentiation. In conclusion, print fidelity of highly concentrated alginate-gellan gum composites was comparable to those of pure alginate; after plotting and crosslinking, the scaffolds possessed improved qualities regarding shape fidelity, mechanical strength, and initial cell attachment making them attractive for tissue engineering applications.

  9. High-Resolution 3-D Imaging and Tissue Differentiation with Transmission Tomography

    Science.gov (United States)

    Marmarelis, V. Z.; Jeong, J.; Shin, D. C.; Do, S.

    A three-dimensional High-resolution Ultrasonic Transmission Tomography (HUTT) system has been developed recently under the sponsorship of the Alfred Mann Institute at the University of Southern California that holds the promise of early detection of breast cancer (mm-size lesions) with greater sensitivity (true positives) and specificity (true negatives) than current x-ray mammograghy. In addition to sub-mm resolution in 3-D, the HUTT system has the unique capability of reliable tissue classification by means of the frequency-dependent attenuation characteristics of individual voxels that are extracted from the tomographic data through novel signal processing methods. These methods yield "multi-band signatures" of the various tissue types that are utilized to achieve reliable tissue differentiation via novel segmentation and classification algorithms. The unparalleled high-resolution and tissue differentiation capabilities of the HUTT system have been demonstrated so far with man-made and animal-tissue phantoms. Illustrative results are presented that corroborate these claims, although several challenges remain to make HUTT a clinically acceptable technology. The next critical step is to collect and analyze data from human subjects (female breasts) in order to demonstrate the key capability of the HUTT system to detect breast lesions early (at the mm-size stage) and to differentiate between malignant and benign lesions in a manner that is far superior (in terms of sensitivity and specificity) to the current x-ray mammography. The key initial application of the HUTT imaging technology is envisioned to be the early (at the mm-size) detection of breast cancer, which represents a major threat to the well-being of women around the world. The potential impact is estimated in hundreds of thousands lives saved, millions of unnecessary biopsies avoided, and billions of dollars saved in national health-care costs every year - to say nothing of the tens of thousands of

  10. Optimal fourth-order staggered-grid finite-difference scheme for 3D frequency-domain viscoelastic wave modeling

    Science.gov (United States)

    Li, Y.; Han, B.; Métivier, L.; Brossier, R.

    2016-09-01

    We investigate an optimal fourth-order staggered-grid finite-difference scheme for 3D frequency-domain viscoelastic wave modeling. An anti-lumped mass strategy is incorporated to minimize the numerical dispersion. The optimal finite-difference coefficients and the mass weighting coefficients are obtained by minimizing the misfit between the normalized phase velocities and the unity. An iterative damped least-squares method, the Levenberg-Marquardt algorithm, is utilized for the optimization. Dispersion analysis shows that the optimal fourth-order scheme presents less grid dispersion and anisotropy than the conventional fourth-order scheme with respect to different Poisson's ratios. Moreover, only 3.7 grid-points per minimum shear wavelength are required to keep the error of the group velocities below 1%. The memory cost is then greatly reduced due to a coarser sampling. A parallel iterative method named CARP-CG is used to solve the large ill-conditioned linear system for the frequency-domain modeling. Validations are conducted with respect to both the analytic viscoacoustic and viscoelastic solutions. Compared with the conventional fourth-order scheme, the optimal scheme generates wavefields having smaller error under the same discretization setups. Profiles of the wavefields are presented to confirm better agreement between the optimal results and the analytic solutions.

  11. Multi-frequency color-marked fringe projection profilometry for fast 3D shape measurement of complex objects.

    Science.gov (United States)

    Jiang, Chao; Jia, Shuhai; Dong, Jun; Bao, Qingchen; Yang, Jia; Lian, Qin; Li, Dichen

    2015-09-21

    We propose a novel multi-frequency color-marked fringe projection profilometry approach to measure the 3D shape of objects with depth discontinuities. A digital micromirror device projector is used to project a color map consisting of a series of different-frequency color-marked fringe patterns onto the target object. We use a chromaticity curve to calculate the color change caused by the height of the object. The related algorithm to measure the height is also described in this paper. To improve the measurement accuracy, a chromaticity curve correction method is presented. This correction method greatly reduces the influence of color fluctuations and measurement error on the chromaticity curve and the calculation of the object height. The simulation and experimental results validate the utility of our method. Our method avoids the conventional phase shifting and unwrapping process, as well as the independent calculation of the object height required by existing techniques. Thus, it can be used to measure complex and dynamic objects with depth discontinuities. These advantages are particularly promising for industrial applications. PMID:26406621

  12. Three-dimensional parallel UNIPIC-3D code for simulations of high-power microwave devices

    Science.gov (United States)

    Wang, Jianguo; Chen, Zaigao; Wang, Yue; Zhang, Dianhui; Liu, Chunliang; Li, Yongdong; Wang, Hongguang; Qiao, Hailiang; Fu, Meiyan; Yuan, Yuan

    2010-07-01

    This paper introduces a self-developed, three-dimensional parallel fully electromagnetic particle simulation code UNIPIC-3D. In this code, the electromagnetic fields are updated using the second-order, finite-difference time-domain method, and the particles are moved using the relativistic Newton-Lorentz force equation. The electromagnetic field and particles are coupled through the current term in Maxwell's equations. Two numerical examples are used to verify the algorithms adopted in this code, numerical results agree well with theoretical ones. This code can be used to simulate the high-power microwave (HPM) devices, such as the relativistic backward wave oscillator, coaxial vircator, and magnetically insulated line oscillator, etc. UNIPIC-3D is written in the object-oriented C++ language and can be run on a variety of platforms including WINDOWS, LINUX, and UNIX. Users can use the graphical user's interface to create the complex geometric structures of the simulated HPM devices, which can be automatically meshed by UNIPIC-3D code. This code has a powerful postprocessor which can display the electric field, magnetic field, current, voltage, power, spectrum, momentum of particles, etc. For the sake of comparison, the results computed by using the two-and-a-half-dimensional UNIPIC code are also provided for the same parameters of HPM devices, the numerical results computed from these two codes agree well with each other.

  13. High-resolution 3D X-ray imaging of intracranial nitinol stents

    Energy Technology Data Exchange (ETDEWEB)

    Snoeren, Rudolph M.; With, Peter H.N. de [Eindhoven University of Technology (TU/e), Faculty Electrical Engineering, Signal Processing Systems group (SPS), Eindhoven (Netherlands); Soederman, Michael [Karolinska University Hospital, Department of Neuroradiology, Stockholm (Sweden); Kroon, Johannes N.; Roijers, Ruben B.; Babic, Drazenko [Philips Healthcare, Best (Netherlands)

    2012-02-15

    To assess an optimized 3D imaging protocol for intracranial nitinol stents in 3D C-arm flat detector imaging. For this purpose, an image quality simulation and an in vitro study was carried out. Nitinol stents of various brands were placed inside an anthropomorphic head phantom, using iodine contrast. Experiments with objects were preceded by image quality and dose simulations. We varied X-ray imaging parameters in a commercially interventional X-ray system to set 3D image quality in the contrast-noise-sharpness space. Beam quality was varied to evaluate contrast of the stents while keeping absorbed dose below recommended values. Two detector formats were used, paired with an appropriate pixel size and X-ray focus size. Zoomed reconstructions were carried out and snapshot images acquired. High contrast spatial resolution was assessed with a CT phantom. We found an optimal protocol for imaging intracranial nitinol stents. Contrast resolution was optimized for nickel-titanium-containing stents. A high spatial resolution larger than 2.1 lp/mm allows struts to be visualized. We obtained images of stents of various brands and a representative set of images is shown. Independent of the make, struts can be imaged with virtually continuous strokes. Measured absorbed doses are shown to be lower than 50 mGy Computed Tomography Dose Index (CTDI). By balancing the modulation transfer of the imaging components and tuning the high-contrast imaging capabilities, we have shown that thin nitinol stent wires can be reconstructed with high contrast-to-noise ratio and good detail, while keeping radiation doses within recommended values. Experimental results compare well with imaging simulations. (orig.)

  14. High frequency energy measurements

    International Nuclear Information System (INIS)

    High-frequency (> 100 MHz) energy measurements present special problems to the experimenter. Environment or available electronics often limit the applicability of a given detector type. The physical properties of many detectors are frequency dependent and in some cases, the physical effect employed can be frequency dependent. State-of-the-art measurements generally involve a detection scheme in association with high-speed electronics and a method of data recording. Events can be single or repetitive shot requiring real time, sampling, or digitizing data recording. Potential modification of the pulse by the detector and the associated electronics should not be overlooked. This presentation will review typical applications, methods of choosing a detector, and high-speed detectors. Special considerations and limitations of some applications and devices will be described

  15. High-performance computational and geostatistical experiments for testing the capabilities of 3-d electrical tomography

    Energy Technology Data Exchange (ETDEWEB)

    Carle, S. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Daily, W. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Newmark, R. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ramirez, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Tompson, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    1999-01-19

    This project explores the feasibility of combining geologic insight, geostatistics, and high-performance computing to analyze the capabilities of 3-D electrical resistance tomography (ERT). Geostatistical methods are used to characterize the spatial variability of geologic facies that control sub-surface variability of permeability and electrical resistivity Synthetic ERT data sets are generated from geostatistical realizations of alluvial facies architecture. The synthetic data sets enable comparison of the "truth" to inversion results, quantification of the ability to detect particular facies at particular locations, and sensitivity studies on inversion parameters

  16. Object data mining and analysis on 3D images of high precision industrial CT

    International Nuclear Information System (INIS)

    There are some areas of interest on 3D images of the high precision industrial CT, such as defects caused during the production process. In order to take a close analysis of these areas, the image processing software Amira was used on the data of a particular work piece sample to do defects segmentation and display, defects measurement. evaluation and documentation. A data set obtained by scanning a vise sample using the lab CT system was analyzed and the results turn out to be fairly good. (authors)

  17. Asymptotic solution for high vorticity regions in incompressible 3D Euler equations

    CERN Document Server

    Agafontsev, D S; Mailybaev, A A

    2016-01-01

    Incompressible 3D Euler equations develop high vorticity in very thin pancake-like regions from generic large-scale initial conditions. In this work we propose an exact solution of the Euler equations for the asymptotic pancake evolution. This solution combines a shear flow aligned with an asymmetric straining flow, and is characterized by a single asymmetry parameter and an arbitrary transversal vorticity profile. The analysis is based on detailed comparison with numerical simulations performed using a pseudo-spectral method in anisotropic grids of up to 972 x 2048 x 4096.

  18. Dense high-aspect ratio 3D carbon pillars on interdigitated microelectrode arrays

    DEFF Research Database (Denmark)

    Amato, Letizia; Heiskanen, Arto; Hansen, Rasmus;

    2015-01-01

    In this work we present high-aspect ratio carbon pillars (1.4 μm in diameter and ∼11 μm in height) on top of interdigitated electrode arrays to be used for electrochemical applications. For this purpose, different types of 2D and 3D pyrolysed carbon structures were fabricated and characterised...... including surface- and microstructure, electrical and electrochemical properties. A pre-treatment of oxidised Si wafers is introduced to eliminate electrode delamination and ensure structure stability in water during long time-experiments. Additionally, a heat treatment method is reported for regeneration...

  19. A CZT high efficiency detector with 3D spatial resolution for Laue lens applications

    DEFF Research Database (Denmark)

    Auricchio, N.; Basili, A.; Caroli, E.;

    2010-01-01

    high performance focal plane detectors in order to exploit to the maximum the intrinsic capabilities of these new high energy telescopes. We describe the ongoing development of a three dimensional (3D) position sensitive device suitable as the basic unit of a high efficiency focal plane detector......For X- and γ-ray astronomy in the coming decades, both ESA and NASA have indicated in their guidelines the importance of developing innovative instrumentation operating in the hard X- and soft γ-ray range where important scientific issues are still open, exploiting high sensitivity (50–100 times...... better than current instruments) for spectroscopic imaging and polarimetric observations. In this framework, the development of new focusing optics based on wide band Laue lenses operating from ∼60 keV up to several hundred keV is particularly challenging. These new high energy focusing optics require...

  20. Design and 3D simulation of a two-cavity wide-gap relativistic klystron amplifier with high power injection

    Science.gov (United States)

    Bai, Xianchen; Yang, Jianhua; Zhang, Jiande

    2012-08-01

    By using an electromagnetic particle-in-cell (PIC) code, an S-band two-cavity wide-gap klystron amplifier (WKA) loaded with washers/rods structure is designed and investigated for high power injection application. Influences of the washers/rods structure on the high frequency characteristics and the basic operation of the amplifier are presented. Generally, the rod structure has great impacts on the space-charge potential depression and the resonant frequency of the cavities. Nevertheless, if only the resonant frequency is tuned to the desired operation frequency, effects of the rod size on the basic operation of the amplifier are expected to be very weak. The 3-dimension (3-D) PIC simulation results show an output power of 0.98 GW corresponding to an efficiency of 33% for the WKA, with a 594 keV, 5 kA electron beam guided by an external magnetic field of 1.5 Tesla. Moreover, if a conductive plane is placed near the output gap, such as the electron collector, the beam potential energy can be further released, and the RF power can be increased to about 1.07 GW with the conversion efficiency of about 36%.

  1. SPADAS: a high-speed 3D single-photon camera for advanced driver assistance systems

    Science.gov (United States)

    Bronzi, D.; Zou, Y.; Bellisai, S.; Villa, F.; Tisa, S.; Tosi, A.; Zappa, F.

    2015-02-01

    Advanced Driver Assistance Systems (ADAS) are the most advanced technologies to fight road accidents. Within ADAS, an important role is played by radar- and lidar-based sensors, which are mostly employed for collision avoidance and adaptive cruise control. Nonetheless, they have a narrow field-of-view and a limited ability to detect and differentiate objects. Standard camera-based technologies (e.g. stereovision) could balance these weaknesses, but they are currently not able to fulfill all automotive requirements (distance range, accuracy, acquisition speed, and frame-rate). To this purpose, we developed an automotive-oriented CMOS single-photon camera for optical 3D ranging based on indirect time-of-flight (iTOF) measurements. Imagers based on Single-photon avalanche diode (SPAD) arrays offer higher sensitivity with respect to CCD/CMOS rangefinders, have inherent better time resolution, higher accuracy and better linearity. Moreover, iTOF requires neither high bandwidth electronics nor short-pulsed lasers, hence allowing the development of cost-effective systems. The CMOS SPAD sensor is based on 64 × 32 pixels, each able to process both 2D intensity-data and 3D depth-ranging information, with background suppression. Pixel-level memories allow fully parallel imaging and prevents motion artefacts (skew, wobble, motion blur) and partial exposure effects, which otherwise would hinder the detection of fast moving objects. The camera is housed in an aluminum case supporting a 12 mm F/1.4 C-mount imaging lens, with a 40°×20° field-of-view. The whole system is very rugged and compact and a perfect solution for vehicle's cockpit, with dimensions of 80 mm × 45 mm × 70 mm, and less that 1 W consumption. To provide the required optical power (1.5 W, eye safe) and to allow fast (up to 25 MHz) modulation of the active illumination, we developed a modular laser source, based on five laser driver cards, with three 808 nm lasers each. We present the full characterization of

  2. 3D Polyaniline Architecture by Concurrent Inorganic and Organic Acid Doping for Superior and Robust High Rate Supercapacitor Performance

    Science.gov (United States)

    Gawli, Yogesh; Banerjee, Abhik; Dhakras, Dipti; Deo, Meenal; Bulani, Dinesh; Wadgaonkar, Prakash; Shelke, Manjusha; Ogale, Satishchandra

    2016-02-01

    A good high rate supercapacitor performance requires a fine control of morphological (surface area and pore size distribution) and electrical properties of the electrode materials. Polyaniline (PANI) is an interesting material in supercapacitor context because it stores energy Faradaically. However in conventional inorganic (e.g. HCl) acid doping, the conductivity is high but the morphological features are undesirable. On the other hand, in weak organic acid (e.g. phytic acid) doping, interesting and desirable 3D connected morphological features are attained but the conductivity is poorer. Here the synergy of the positive quality factors of these two acid doping approaches is realized by concurrent and optimized strong-inorganic (HCl) and weak-organic (phytic) acid doping, resulting in a molecular composite material that renders impressive and robust supercapacitor performance. Thus, a nearly constant high specific capacitance of 350 F g-1 is realized for the optimised case of binary doping over the entire range of 1 A g-1 to 40 A g-1 with stability of 500 cycles at 40 A g-1. Frequency dependant conductivity measurements show that the optimized co-doped case is more metallic than separately doped materials. This transport property emanates from the unique 3D single molecular character of such system.

  3. 3-D space time kinetics of compact high temperature reactor with fuel temperature feedback

    International Nuclear Information System (INIS)

    The Compact High Temperature Reactor (CHTR) is being developed as technology demonstrator for Indian High Temperature Reactor programme. Physics design of conceptual core of (Th-233U) fuelled CHTR is in advance stage and various core configurations have been proposed. Reactor core operation at high temperature necessitates sophisticated safety and anticipated transients analyses including postulated LORA, LOCA, and power set-back transients in CHTR. Recently, efficient IQS module in ARCH with adiabatic fuel temperature feedback capability has been developed. For accounting fuel and coolant temperature feedbacks in the simulation of 3D space time transients in CHTR, module for 1D (radial) heat conduction based module for heat transfer from fuel to coolant has been incorporated in 3D space-time analysis code ARCH. The AER benchmarking results of ARCH-IQS code with Doppler feedback and results of anticipated transient without scram (ATWS) of (Th-233U) fuelled CHTR with the present capability in ARCH-IQS code have been presented in this paper. (author)

  4. Focus Variation - A New Technology for High Resolution Optical 3D Surface Metrology

    Science.gov (United States)

    Scherer, S.

    2009-04-01

    Focus Variation - A New Technology for High Resolution Optical 3D Surface Metrology S. Scherer1, E. Cristea1, O. Huber1, A. Krenn1 1 ALICONA GmbH Graz, Austria The need for increasing accuracy is a characteristic of all geo-applications, and hence of the instruments contributing to obtaining relevant data. Small and fine sensors are being developed, measuring different parameters of our geosystem and requiring continuous validation and calibration. These sensors have often very small components (fine sensors able to sense dust, atmospheric water vapour characteristics, pressure change, gravimeters, satellite micro-components), showing complex topographies including steep flanks and having varying reflective properties. In order to get valid and reliable results, quality assurance of these instruments and sensors is required. The optical technology Focus-Variation, developed by Alicona and added in the latest draft of the upcoming ISO standard 25178, provides high resolution 3D surface metrology even at those complex topographies. The technique of Focus-Variation combines the small depth of focus of an optical system with vertical scanning to provide topographical and color information from the variation of focus. It is used for high-resolution optical 3D surface measurements. The traceable and repeatable measurement results are further being used for calibration and validation purposes. Some of the characteristics of the technology are: - Measurement of instruments / samples with steep flanks up to 80° - Measurement of materials with strongly varying reflection properties - Measurement of surfaces presenting fine (from 10nm) or strong roughness Here, we present the operating principle and possible applications of the optical 3D measurement system "InfiniteFocus", which is based on the technology of Focus-Variation and used for quality assurance in the lab and in production. With the vertical resolution of up to 10nm, InfiniteFocus yields meaningful form and

  5. High frequency electromagnetic dosimetry

    CERN Document Server

    Sánchez-Hernández, David A

    2009-01-01

    Along with the growth of RF and microwave technology applications, there is a mounting concern about the possible adverse effects over human health from electromagnetic radiation. Addressing this issue and putting it into perspective, this groundbreaking resource provides critical details on the latest advances in high frequency electromagnetic dosimetry.

  6. 3D-image-guided high-dose-rate intracavitary brachytherapy for salvage treatment of locally persistent nasopharyngeal carcinoma

    OpenAIRE

    Ren, Yu-Feng; Cao, Xin-Ping; Xu, Jia; Ye, Wei-Jun; Gao, Yuan-Hong; Teh, Bin S.; Wen, Bi-Xiu

    2013-01-01

    Background To evaluate the therapeutic benefit of 3D-image-guided high-dose-rate intracavitary brachytherapy (3D-image-guided HDR-BT) used as a salvage treatment of intensity modulated radiation therapy (IMRT) in patients with locally persistent nasopharyngeal carcinoma (NPC). Methods Thirty-two patients with locally persistent NPC after full dose of IMRT were evaluated retrospectively. 3D-image-guided HDR-BT treatment plan was performed on a 3D treatment planning system (PLATO BPS 14.2). The...

  7. 3D-printed surface mould applicator for high-dose-rate brachytherapy

    Science.gov (United States)

    Schumacher, Mark; Lasso, Andras; Cumming, Ian; Rankin, Adam; Falkson, Conrad B.; Schreiner, L. John; Joshi, Chandra; Fichtinger, Gabor

    2015-03-01

    In contemporary high-dose-rate brachytherapy treatment of superficial tumors, catheters are placed in a wax mould. The creation of current wax models is a difficult and time consuming proces.The irradiation plan can only be computed post-construction and requires a second CT scan. In case no satisfactory dose plan can be created, the mould is discarded and the process is repeated. The objective of this work was to develop an automated method to replace suboptimal wax moulding. We developed a method to design and manufacture moulds that guarantee to yield satisfactory dosimetry. A 3D-printed mould with channels for the catheters designed from the patient's CT and mounted on a patient-specific thermoplastic mesh mask. The mould planner was implemented as an open-source module in the 3D Slicer platform. Series of test moulds were created to accommodate standard brachytherapy catheters of 1.70mm diameter. A calibration object was used to conclude that tunnels with a diameter of 2.25mm, minimum 12mm radius of curvature, and 1.0mm open channel gave the best fit for this printer/catheter combination. Moulds were created from the CT scan of thermoplastic mesh masks of actual patients. The patient-specific moulds have been visually verified to fit on the thermoplastic meshes. The masks were visually shown to fit onto the thermoplastic meshes, next the resulting dosimetry will have to be compared with treatment plans and dosimetry achieved with conventional wax moulds in order to validate our 3D printed moulds.

  8. 3D Reconstruction of the Vortex in a Human Right Ventricle Model using High Speed PIV

    Science.gov (United States)

    Kheradvar, Arash; Falahatpisheh, Ahmad

    2011-11-01

    This work aims to characterize the formation process and translation of the vortex, which forms along with the trans-tricuspid jet in a realistic model of a human right ventricle (RV). A clear model of the RV made of silicone rubber was carefully casted in real size from echocardiographic data of an adult human heart. The RV model was used in our heart pulsed-flow simulator at KLAB at UCI to perform experiments. Bioprosthetic heart valves in appropriate sizes were used at tricuspid and pulmonary positions. Multi-planar high-speed PIV was performed to capture and reconstruct the 3D flow field with a 1-millisecond time gap between each two velocity frames. λ2 iso-surfaces were used to illustrate the evolution of vortex cores. The highly asymmetric shape of the RV chamber results in a complex 3D trans-tricuspid vortex that forms and translates toward right ventricular outflow tract, and finally departs RV from pulmonary valve. Through this study, -for the first time- the formation, evolution and pathway of the RV vortex have been characterized in vitro.

  9. Dense 3D Reconstruction from High Frame-Rate Video Using a Static Grid Pattern.

    Science.gov (United States)

    Sagawa, Ryusuke; Furukawa, Ryo; Kawasaki, Hiroshi

    2014-09-01

    Dense 3D reconstruction of fast moving objects could contribute to various applications such as body structure analysis, accident avoidance, and so on. In this paper, we propose a technique based on a one-shot scanning method, which reconstructs 3D shapes for each frame of a high frame-rate video capturing the scenes projected by a static pattern. To avoid instability of image processing, we restrict the number of colors used in the pattern to less than two. The proposed technique comprises (1) an efficient algorithm to eliminate ambiguity of projected parallel-line patterns by using intersection points, (2) a batch reconstruction algorithm of multiple frames by using spatio-temporal constraints, and (3) an efficient detection method of color-encoded grid pattern based on de Bruijn sequence. In the experiments, the line detection algorithm worked effectively and the dense reconstruction algorithm produces accurate and robust results. We also show the improved results by using temporal constraints. Finally, the dense reconstructions of fast moving objects in a high frame-rate video are presented. PMID:26352228

  10. 3D cut-cell modelling for high-resolution atmospheric simulations

    CERN Document Server

    Yamazaki, H; Nikiforakis, N

    2015-01-01

    With the recent, rapid development of computer technology, the resolution of atmospheric numerical models has increased substantially. As a result, steep gradients in mountainous terrain are now being resolved in high-resolution models. This results in large truncation errors in those models using terrain-following coordinates. In this study, a new 3D Cartesian coordinate non-hydrostatic atmospheric model is developed. A cut-cell representation of topography based on finite-volume discretization is combined with a cell-merging approach, in which small cut-cells are merged with neighboring cells either vertically or horizontally. In addition, a block-structured mesh-refinement technique achieves a variable resolution on the model grid with the finest resolution occurring close to the terrain surface. The model successfully reproduces a flow over a 3D bell-shaped hill that shows a good agreement with the flow predicted by the linear theory. The ability of the model to simulate flows over steep terrain is demons...

  11. Early Earth plume-lid tectonics: A high-resolution 3D numerical modelling approach

    Science.gov (United States)

    Fischer, R.; Gerya, T.

    2016-10-01

    Geological-geochemical evidence point towards higher mantle potential temperature and a different type of tectonics (global plume-lid tectonics) in the early Earth (>3.2 Ga) compared to the present day (global plate tectonics). In order to investigate tectono-magmatic processes associated with plume-lid tectonics and crustal growth under hotter mantle temperature conditions, we conduct a series of 3D high-resolution magmatic-thermomechanical models with the finite-difference code I3ELVIS. No external plate tectonic forces are applied to isolate 3D effects of various plume-lithosphere and crust-mantle interactions. Results of the numerical experiments show two distinct phases in coupled crust-mantle evolution: (1) a longer (80-100 Myr) and relatively quiet 'growth phase' which is marked by growth of crust and lithosphere, followed by (2) a short (∼20 Myr) and catastrophic 'removal phase', where unstable parts of the crust and mantle lithosphere are removed by eclogitic dripping and later delamination. This modelling suggests that the early Earth plume-lid tectonic regime followed a pattern of episodic growth and removal also called episodic overturn with a periodicity of ∼100 Myr.

  12. High-resolution 3D seismic model of the crustal and uppermost mantle structure in Poland

    Science.gov (United States)

    Grad, Marek; Polkowski, Marcin; Ostaficzuk, Stanisław R.

    2016-01-01

    In the area of Poland a contact between the Precambrian and Phanerozoic Europe and the Carpathians has a complicated structure and a complex P-wave velocity of the sedimentary cover, crystalline crust, Moho depth and the uppermost mantle. The geometry of the uppermost several kilometers of sediments is relatively well recognized from over 100,000 boreholes. The vertical seismic profiling (VSP) from 1188 boreholes provided detailed velocity data for regional tectonic units and for stratigraphic successions from Permian to the Tertiary and Quaternary deposits. These data, however, do not provide information about the velocity and basement depth in the central part of the Trans-European suture zone (TESZ) and in the Carpathians. So, the data set is supplemented by 2D velocity models from 32 deep seismic sounding refraction profiles which also provide information about the crust and uppermost mantle. Together with the results of other methods: vertical seismic profiling, magnetotelluric, allow for the creation of a detailed, high-resolution 3D model for the entire Earth's crust and the uppermost mantle down to a depth of 60 km. The thinnest sedimentary cover in the Mazury-Belarus anteclise is only 0.3 to 1 km thick, which increases to 7 to 8 km along the East European Craton (EEC) margin, and 9 to 12 km in the TESZ. The Variscan domain is characterized by a 1-4 km thick sedimentary cover, while the Carpathians are characterized by very thick sedimentary layers, up to about 20 km. The crystalline crust is differentiated and has a layered structure. The crust beneath the West European Platform (WEP; Variscan domain) is characterized by P-wave velocities of 5.8-6.6 km/s. The upper and middle crusts beneath the EEC are characterized by velocities of 6.1-6.6 km/s, and are underlain by a high velocity lower crust with a velocity of about 7 km/s. A general decrease in velocity is observed from the older to the younger tectonic domains. The TESZ is associated with a steep dip

  13. Effect of high magnetic field on a quasi-3D silver dendrite growing system

    Science.gov (United States)

    Tang, Fengzhi; Katsuki, Akio; Tanimoto, Yoshifumi

    2006-05-01

    The Ag+/Cu liquid-solid redox reaction was investigated in a vertical and inhomogeneous high magnetic field (up to 15 T). According to a comparison between the morphologies of quasi-3D silver dendrites generated under different magnetic flux densities, the imposition of a high magnetic field strongly affected the aggregation process of the silver dendrites. The present experiment used four kinds of liquid-solid boundaries, which are affected by the reaction direction and solution condition, as bases for the diffusion limited aggregation (DLA)-like dendritic growth of silver deposition. Results are interpreted in terms of convections of the aqueous solution and a tentative quantitative analysis of forces acting on particles arising from the magnetic field. A new force is predicted theoretically and is discussed in detail.

  14. A nanofiber based artificial electronic skin with high pressure sensitivity and 3D conformability

    Science.gov (United States)

    Zhong, Weibin; Liu, Qiongzhen; Wu, Yongzhi; Wang, Yuedan; Qing, Xing; Li, Mufang; Liu, Ke; Wang, Wenwen; Wang, Dong

    2016-06-01

    Pressure sensors with 3D conformability are highly desirable components for artificial electronic skin or e-textiles that can mimic natural skin, especially for application in real-time monitoring of human physiological signals. Here, a nanofiber based electronic skin with ultra-high pressure sensitivity and 3D conformability is designed and built by interlocking two elastic patterned nanofibrous membranes. The patterned membrane is facilely prepared by casting conductive nanofiber ink into a silicon mould to form an array of semi-spheroid-like protuberances. The protuberances composed of intertwined elastic POE nanofibers and PPy@PVA-co-PE nanofibers afford a tunable effective elastic modulus that is capable of capturing varied strains and stresses, thereby contributing to a high sensitivity for pressure sensing. This electronic skin-like sensor demonstrates an ultra-high sensitivity (1.24 kPa-1) below 150 Pa with a detection limit as low as about 1.3 Pa. The pixelated sensor array and a RGB-LED light are then assembled into a circuit and show a feasibility for visual detection of spatial pressure. Furthermore, a nanofiber based proof-of-concept wireless pressure sensor with a bluetooth module as a signal transmitter is proposed and has demonstrated great promise for wireless monitoring of human physiological signals, indicating a potential for large scale wearable electronic devices or e-skin.Pressure sensors with 3D conformability are highly desirable components for artificial electronic skin or e-textiles that can mimic natural skin, especially for application in real-time monitoring of human physiological signals. Here, a nanofiber based electronic skin with ultra-high pressure sensitivity and 3D conformability is designed and built by interlocking two elastic patterned nanofibrous membranes. The patterned membrane is facilely prepared by casting conductive nanofiber ink into a silicon mould to form an array of semi-spheroid-like protuberances. The

  15. PolyHIPE Derived Freestanding 3D Carbon Foam for Cobalt Hydroxide Nanorods Based High Performance Supercapacitor

    Science.gov (United States)

    Patil, Umakant M.; Ghorpade, Ravindra V.; Nam, Min Sik; Nalawade, Archana C.; Lee, Sangrae; Han, Haksoo; Jun, Seong Chan

    2016-01-01

    The current paper describes enhanced electrochemical capacitive performance of chemically grown Cobalt hydroxide (Co(OH)2) nanorods (NRs) decorated porous three dimensional graphitic carbon foam (Co(OH)2/3D GCF) as a supercapacitor electrode. Freestanding 3D porous GCF is prepared by carbonizing, high internal phase emulsion (HIPE) polymerized styrene and divinylbenzene. The PolyHIPE was sulfonated and carbonized at temperature up to 850 °C to obtain graphitic 3D carbon foam with high surface area (389 m2 g−1) having open voids (14 μm) interconnected by windows (4 μm) in monolithic form. Moreover, entangled Co(OH)2 NRs are anchored on 3D GCF electrodes by using a facile chemical bath deposition (CBD) method. The wide porous structure with high specific surface area (520 m2 g−1) access offered by the interconnected 3D GCF along with Co(OH)2 NRs morphology, displays ultrahigh specific capacitance, specific energy and power. The Co(OH)2/3D GCF electrode exhibits maximum specific capacitance about ~1235 F g−1 at ~1 A g−1 charge-discharge current density, in 1 M aqueous KOH solution. These results endorse potential applicability of Co(OH)2/3D GCF electrode in supercapacitors and signifies that, the porous GCF is a proficient 3D freestanding framework for loading pseudocapacitive nanostructured materials. PMID:27762284

  16. Numerical 3D analysis of cloud cavitation shedding frequency on a circular leading edge hydrofoil with a barotropic cavitation model

    Science.gov (United States)

    Blume, M.; Skoda, R.

    2015-12-01

    A compressible density-based time-explicit low Mach number consistent viscous flow solver is utilised in combination with a barotropic cavitation model for the analysis of cloud cavitation on a circular leading edge (CLE) hydrofoil. For 5° angle of attack, cloud structure and shedding frequency for different cavitation numbers are compared to experimental data. A strong grid sensitivity is found in particular for high cavitation numbers. On a fine grid, a very good agreement with validation data is achieved even without explicit turbulence model. The neglect of viscous effects as well as a two-dimensional set-up lead to a less realistic prediction of cloud structures and frequencies. Comparative simulations with the Sauer-Schnerr cavitation model and modified pre-factors of the mass transfer terms underestimate the measured shedding frequency.

  17. Nitrogen-doped 3D macroporous graphene frameworks as anode for high performance lithium-ion batteries

    Science.gov (United States)

    Liu, Xiaowu; Wu, Ying; Yang, Zhenzhong; Pan, Fusen; Zhong, Xiongwu; Wang, Jiaqing; Gu, Lin; Yu, Yan

    2015-10-01

    Nitrogen-doped 3D graphene frameworks (N-3D GFs) were synthesized by a facile two-step method: Polystyrene (PS) encapsulated in graphene oxide (GO) composites (denoted as PS@GO) are first synthesized, followed by a post-thermal annealing in ammonia step to get N-doped 3D GFs. The resulting N-3D GFs inherit the advantages of graphene, which possesses high electrical conductivity and high specific surface area. Furthermore, the well-defined 3D interconnected structure can facilitate the access of the electrolyte to the electrode surface, thus shortening the diffusion length of both Li+/e-, keeping the overall electrode highly conductive and active in lithium storage. Simultaneously, the in-situ formation of pyridinic N and pyrrolic N in 3D GFs provide high electronic conductivity and structure stability for lithium storage. The designed N-3D GFs electrode delivers a high specific capacity of 1094 mAhg-1 after 100 cycles at 200 mAg-1 and superior rate capability (691 mAhg-1 after 500 cycles at 1000 mAg-1) when used as anode for LIBs. We believe that such an inherently inexpensive, scalable, facile method can significantly increase the feasibility of building high performance energy storage system.

  18. High-energy particle transport in 3D hydrodynamic models of colliding-wind binaries

    CERN Document Server

    Reitberger, K; Reimer, A; Dubus, G; Reimer, O

    2014-01-01

    Massive stars in binary systems (as WR140, WR147 or $\\eta$ Carinae) have long been regarded as potential sources of high-energy $\\gamma$-rays. The emission is thought to arise in the region where the stellar winds collide and produce relativistic particles which subsequently might be able to emit $\\gamma$-rays. Detailed numerical hydrodynamic simulations have already offered insight in the complex dynamics of the wind collision region (WCR), while independent analytical studies, albeit with simplified descriptions of the WCR, have shed light on the spectra of charged particles. In this paper, we describe a combination of these two approaches. We present a 3D-hydrodynamical model for colliding stellar winds and compute spectral energy distributions of relativistic particles for the resulting structure of the WCR. The hydrodynamic part of our model incorporates the line-driven acceleration of the winds, gravity, orbital motion and the radiative cooling of the shocked plasma. In our treatment of charged particle...

  19. Reversible Assembly of Graphitic Carbon Nitride 3D Network for Highly Selective Dyes Absorption and Regeneration.

    Science.gov (United States)

    Zhang, Yuye; Zhou, Zhixin; Shen, Yanfei; Zhou, Qing; Wang, Jianhai; Liu, Anran; Liu, Songqin; Zhang, Yuanjian

    2016-09-27

    Responsive assembly of 2D materials is of great interest for a range of applications. In this work, interfacial functionalized carbon nitride (CN) nanofibers were synthesized by hydrolyzing bulk CN in sodium hydroxide solution. The reversible assemble and disassemble behavior of the as-prepared CN nanofibers was investigated by using CO2 as a trigger to form a hydrogel network at first. Compared to the most widespread absorbent materials such as active carbon, graphene and previously reported supramolecular gel, the proposed CN hydrogel not only exhibited a competitive absorbing capacity (maximum absorbing capacity of methylene blue up to 402 mg/g) but also overcame the typical deficiencies such as poor selectivity and high energy-consuming regeneration. This work would provide a strategy to construct a 3D CN network and open an avenue for developing smart assembly for potential applications ranging from environment to selective extraction.

  20. High-resolution 3D analysis of mouse small-intestinal stroma.

    Science.gov (United States)

    Bernier-Latmani, Jeremiah; Petrova, Tatiana V

    2016-09-01

    Here we detail a protocol for whole-mount immunostaining of mouse small-intestinal villi that can be used to generate high-resolution 3D images of all gut cell types, including blood and lymphatic vessel cells, neurons, smooth muscle cells, fibroblasts and immune cells. The procedure describes perfusion, fixation, dissection, immunostaining, mounting, clearing, confocal imaging and quantification, using intestinal vasculature as an example. As intestinal epithelial cells prevent visualization with some antibodies, we also provide an optional protocol to remove these cells before fixation. In contrast to alternative current techniques, our protocol enables the entire villus to be visualized with increased spatial resolution of cell location, morphology and cell-cell interactions, thus allowing for easy quantification of phenotypes. The technique, which takes 7 d from mouse dissection to microscopic examination, will be useful for researchers who are interested in most aspects of intestinal biology, including mucosal immunology, infection, nutrition, cancer biology and intestinal microbiota. PMID:27560169

  1. Development of Focused Ion Beam technique for high speed steel 3D-SEM artefact fabrication

    DEFF Research Database (Denmark)

    Carli, Lorenzo; MacDonald, A. Nicole; De Chiffre, Leonardo;

    2009-01-01

    The work describes preliminary manufacture by grinding, followed by machining on a Focused Ion Beam (FIB), of a high speed steel step artefact for 3D-SEM calibration. The FIB is coupled with a SEM in the so called dual beam instrument. The milling capabilities of FIB were checked from a qualitative...... point of view, using the dual beam SEM imaging, and quantitatively using a reference stylus instrument, to establish traceability. A triangular section having a depth of about 10 μm was machined, where the 50 μm curvature radius due to grinding was reduced to about 2 μm by FIB milling...... as it was estimated using the dual beam SEM....

  2. Development and Evaluation of High-Performance Decorrelation Algorithms for the Nonalternating 3D Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Quiles FJ

    2007-01-01

    Full Text Available We introduce and evaluate the implementations of three parallel video-sequences decorrelation algorithms. The proposed algorithms are based on the nonalternating classic three-dimensional wavelet transform (3D-WT. The parallel implementations of the algorithms are developed and tested on a shared memory system, an SGI origin 3800 supercomputer making use of a message-passing paradigm. We evaluate and analyze the performance of the implementations in terms of the response time and speed-up factor by varying the number of processors and various video coding parameters. The key points enabling the development of highly efficient implementations rely on the partitioning of the video sequences into groups of frames and a workload distribution strategy supplemented by the use of parallel I/O primitives, for better exploiting the inherent features of the application and computing platform. We also evaluate the effectiveness of our algorithms in terms of the first-order entropy.

  3. 3D imaging provides a high-resolution, volumetric approach for analyzing biofouling.

    Science.gov (United States)

    First, Matthew R; Policastro, Steven A; Strom, Matthew J; Riley, Scott C; Robbins-Wamsley, Stephanie H; Drake, Lisa A

    2014-01-01

    A volumetric approach for determining the fouling burden on surfaces is presented, consisting of a 3D camera imaging system with fine (5 μm) resolution. Panels immersed in an estuary on the southwest coast of Florida, USA were imaged and the data were used to quantify seasonal changes in the biofouling community. Test panels, which were submerged in seawater for up to one year, were analyzed before and after gentle scrubbing to quantify the biovolume of the total fouling community (ie soft and hard organisms) and the hard fouling community. Total biofouling ranged from 0.01 to 1.16 cm(3) cm(-2) throughout the immersion period; soft fouling constituted 22-87% of the total biovolume. In the future, this approach may be used to inform numerical models of fluid-surface interfaces and to evaluate, with high resolution, the morphology of fouling organisms in response to antifouling technologies.

  4. Portable high-intensity focused ultrasound system with 3D electronic steering, real-time cavitation monitoring, and 3D image reconstruction algorithms: a preclinical study in pigs

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jin Woo; Lee, Jae Young; Hwang, Eui Jin; Hwang, In Pyeong; Woo, Sung Min; Lee, Chang Joo; Park, Eun Joo; Choi, Byung Ihn [Dept. of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, Seoul (Korea, Republic of)

    2014-10-15

    The aim of this study was to evaluate the safety and accuracy of a new portable ultrasonography-guided high-intensity focused ultrasound (USg-HIFU) system with a 3-dimensional (3D) electronic steering transducer, a simultaneous ablation and imaging module, real-time cavitation monitoring, and 3D image reconstruction algorithms. To address the accuracy of the transducer, hydrophones in a water chamber were used to assess the generation of sonic fields. An animal study was also performed in five pigs by ablating in vivo thighs by single-point sonication (n=10) or volume sonication (n=10) and ex vivo kidneys by single-point sonication (n=10). Histological and statistical analyses were performed. In the hydrophone study, peak voltages were detected within 1.0 mm from the targets on the y- and z-axes and within 2.0-mm intervals along the x-axis (z-axis, direction of ultrasound propagation; y- and x-axes, perpendicular to the direction of ultrasound propagation). Twenty-nine of 30 HIFU sessions successfully created ablations at the target. The in vivo porcine thigh study showed only a small discrepancy (width, 0.5-1.1 mm; length, 3.0 mm) between the planning ultrasonograms and the pathological specimens. Inordinate thermal damage was not observed in the adjacent tissues or sonic pathways in the in vivo thigh and ex vivo kidney studies. Our study suggests that this new USg-HIFU system may be a safe and accurate technique for ablating soft tissues and encapsulated organs.

  5. Laser processes and analytics for high power 3D battery materials

    Science.gov (United States)

    Pfleging, W.; Zheng, Y.; Mangang, M.; Bruns, M.; Smyrek, P.

    2016-03-01

    Laser processes for cutting, modification and structuring of energy storage materials such as electrodes, separator materials and current collectors have a great potential in order to minimize the fabrication costs and to increase the performance and operational lifetime of high power lithium-ion-batteries applicable for stand-alone electric energy storage devices and electric vehicles. Laser direct patterning of battery materials enable a rather new technical approach in order to adjust 3D surface architectures and porosity of composite electrode materials such as LiCoO2, LiMn2O4, LiFePO4, Li(NiMnCo)O2, and Silicon. The architecture design, the increase of active surface area, and the porosity of electrodes or separator layers can be controlled by laser processes and it was shown that a huge impact on electrolyte wetting, lithium-ion diffusion kinetics, cell life-time and cycling stability can be achieved. In general, the ultrafast laser processing can be used for precise surface texturing of battery materials. Nevertheless, regarding cost-efficient production also nanosecond laser material processing can be successfully applied for selected types of energy storage materials. A new concept for an advanced battery manufacturing including laser materials processing is presented. For developing an optimized 3D architecture for high power composite thick film electrodes electrochemical analytics and post mortem analytics using laser-induced breakdown spectroscopy were performed. Based on mapping of lithium in composite electrodes, an analytical approach for studying chemical degradation in structured and unstructured lithium-ion batteries will be presented.

  6. Feasibility analysis of high resolution tissue image registration using 3-D synthetic data

    Directory of Open Access Journals (Sweden)

    Yachna Sharma

    2011-01-01

    Full Text Available Background: Registration of high-resolution tissue images is a critical step in the 3D analysis of protein expression. Because the distance between images (~4-5μm thickness of a tissue section is nearly the size of the objects of interest (~10-20μm cancer cell nucleus, a given object is often not present in both of two adjacent images. Without consistent correspondence of objects between images, registration becomes a difficult task. This work assesses the feasibility of current registration techniques for such images. Methods: We generated high resolution synthetic 3-D image data sets emulating the constraints in real data. We applied multiple registration methods to the synthetic image data sets and assessed the registration performance of three techniques (i.e., mutual information (MI, kernel density estimate (KDE method [1], and principal component analysis (PCA at various slice thicknesses (with increments of 1μm in order to quantify the limitations of each method. Results: Our analysis shows that PCA, when combined with the KDE method based on nuclei centers, aligns images corresponding to 5μm thick sections with acceptable accuracy. We also note that registration error increases rapidly with increasing distance between images, and that the choice of feature points which are conserved between slices improves performance. Conclusions: We used simulation to help select appropriate features and methods for image registration by estimating best-case-scenario errors for given data constraints in histological images. The results of this study suggest that much of the difficulty of stained tissue registration can be reduced to the problem of accurately identifying feature points, such as the center of nuclei.

  7. 3D Reconstruction of Human Laryngeal Dynamics Based on Endoscopic High-Speed Recordings.

    Science.gov (United States)

    Semmler, Marion; Kniesburges, Stefan; Birk, Veronika; Ziethe, Anke; Patel, Rita; Dollinger, Michael

    2016-07-01

    Standard laryngoscopic imaging techniques provide only limited two-dimensional insights into the vocal fold vibrations not taking the vertical component into account. However, previous experiments have shown a significant vertical component in the vibration of the vocal folds. We present a 3D reconstruction of the entire superior vocal fold surface from 2D high-speed videoendoscopy via stereo triangulation. In a typical camera-laser set-up the structured laser light pattern is projected on the vocal folds and captured at 4000 fps. The measuring device is suitable for in vivo application since the external dimensions of the miniaturized set-up barely exceed the size of a standard rigid laryngoscope. We provide a conservative estimate on the resulting resolution based on the hardware components and point out the possibilities and limitations of the miniaturized camera-laser set-up. In addition to the 3D vocal fold surface, we extended previous approaches with a G2-continuous model of the vocal fold edge. The clinical applicability was successfully established by the reconstruction of visual data acquired from 2D in vivo high-speed recordings of a female and a male subject. We present extracted dynamic parameters like maximum amplitude and velocity in the vertical direction. The additional vertical component reveals deeper insights into the vibratory dynamics of the vocal folds by means of a non-invasive method. The successful miniaturization allows for in vivo application giving access to the most realistic model available and hence enables a comprehensive understanding of the human phonation process. PMID:26829782

  8. Performance analysis of high quality parallel preconditioners applied to 3D finite element structural analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kolotilina, L.; Nikishin, A.; Yeremin, A. [and others

    1994-12-31

    The solution of large systems of linear equations is a crucial bottleneck when performing 3D finite element analysis of structures. Also, in many cases the reliability and robustness of iterative solution strategies, and their efficiency when exploiting hardware resources, fully determine the scope of industrial applications which can be solved on a particular computer platform. This is especially true for modern vector/parallel supercomputers with large vector length and for modern massively parallel supercomputers. Preconditioned iterative methods have been successfully applied to industrial class finite element analysis of structures. The construction and application of high quality preconditioners constitutes a high percentage of the total solution time. Parallel implementation of high quality preconditioners on such architectures is a formidable challenge. Two common types of existing preconditioners are the implicit preconditioners and the explicit preconditioners. The implicit preconditioners (e.g. incomplete factorizations of several types) are generally high quality but require solution of lower and upper triangular systems of equations per iteration which are difficult to parallelize without deteriorating the convergence rate. The explicit type of preconditionings (e.g. polynomial preconditioners or Jacobi-like preconditioners) require sparse matrix-vector multiplications and can be parallelized but their preconditioning qualities are less than desirable. The authors present results of numerical experiments with Factorized Sparse Approximate Inverses (FSAI) for symmetric positive definite linear systems. These are high quality preconditioners that possess a large resource of parallelism by construction without increasing the serial complexity.

  9. Robust automatic high resolution segmentation of SOFC anode porosity in 3D

    DEFF Research Database (Denmark)

    Jørgensen, Peter Stanley; Bowen, Jacob R.

    2008-01-01

    anode in 3D. The technique is based on numerical approximations to partial differential equations to evolve a 3D surface to the desired phase boundary. Vector fields derived from the experimentally acquired data are used as the driving force. The automatic segmentation compared to manual delineation...

  10. High-frequency ventilation.

    Science.gov (United States)

    Crawford, M R

    1986-08-01

    Over the last six years high-frequency ventilation has been extensively evaluated both in the clinical and laboratory settings. It is now no longer the great mystery it once was, and it is now no longer believed (as many had hoped), that it will solve all the problems associated with mechanical pulmonary ventilation. Although the technique is safe and appears to cause no harm even in the long term, it has not yet been shown to offer any major advantages over conventional mechanical ventilation. PMID:3530042

  11. High-Efficiency Solar-Powered 3-D Printers for Sustainable Development

    Directory of Open Access Journals (Sweden)

    Jephias Gwamuri

    2016-01-01

    Full Text Available The release of the open source 3-D printer known as the RepRap (a self-Replicating Rapid prototyper resulted in the potential for distributed manufacturing of products for significantly lower costs than conventional manufacturing. This development, coupled with open source-appropriate technology (OSAT, has enabled the opportunity for 3-D printers to be used for sustainable development. In this context, OSAT provides the opportunity to modify and improve the physical designs of their printers and desired digitally-shared objects. However, these 3-D printers require electricity while more than a billion people still lack electricity. To enable the utilization of RepRaps in off-grid communities, solar photovoltaic (PV-powered mobile systems have been developed, but recent improvements in novel delta-style 3-D printer designs allows for reduced costs and improved performance. This study builds on these innovations to develop and experimentally validate a mobile solar-PV-powered delta 3-D printer system. It is designed to run the RepRap 3-D printer regardless of solar flux. The electrical system design is tested outdoors for operating conditions: (1 PV charging battery and running 3-D printer; (2 printing under low insolation; (3 battery powering the 3-D printer alone; (4 PV charging the battery only; and (5 battery fully charged with PV-powered 3-D printing. The results show the system performed as required under all conditions providing feasibility for adoption in off-grid rural communities. 3-D printers powered by affordable mobile PV solar systems have a great potential to reduce poverty through employment creation, as well as ensuring a constant supply of scarce products for isolated communities.

  12. Characteristics of neurovascular compression in facial neuralgia patients by 3D high-resolution MRI and fusion technology

    Institute of Scientific and Technical Information of China (English)

    Zi-Yi Guo; Jing Chen; Guang Yang; Qian-Yu Tang; Cai-Xiang Chen; Shui-Xi Fu; Dan Yu

    2012-01-01

    Objective: To evaluate the anatomical characteristics and patterns of neurovascular compression in patients suffering trigeminal neuralgia, using 3D high-resolution magnetic resonance imaging methods and fusion technologies. Methods: The analysis of the anatomy of the facial nerve, brain stem and the vascular structures related to this nerve was made in 100 consecutive patients for TN. 3D high resolution MRI studies (3D SPGR, T1 enhanced 3D MP-RAGE and T2/T1 3D FIESTA) simultaneous visualization were used to assessed using the software 3D DOCTOR. Results: In 93 patients (93%), there were one or several locals of neurovascular compression (NVC). The superior cerebellar artery was involved in 71 cases (76%), the other vessels including the antero-inferior cerebellar artery, the basilar artery, the vertebral artery, and some venous structures. The mean distance between NVC and nerve origin site in the brainstem was (3.76 ± 2.90) mm). In 39 patients (42%), the vascular compression was located proximally and in 42 (45%) the compression was located distally. Nerve dislocation or distortion by the vessel was observed in 30 cases (32%). Conclusions: This 3D high resolution MRI and image fusion technology could be useful for diagnostic and therapeutic decisions in TN.

  13. Continuous frequency and phase spectrograms: a study of their 2D and 3D capabilities and application to musical signal analysis

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new lighting and enlargement on phase spectrogram (PS) and frequency spectrogram (FS) is presented in this paper.These representations result from the coupling of power spectrogram and short time Fourier transform (STFT). The main contribution is the construction of the 3D phase spectrogram (3DPS) and the 3D frequency spectrogram (3DFS). These new tools allow such specific test signals as small slope linear chirp, phase jump and small frequency jump to be analyzed. An application case of musical signal analysis is reported. The main objective is to detect small frequency and phase variations in order to characterize each type of sound attack without losing the amplitude information given by power spectrogram.

  14. Closed-loop high-speed 3D thermal probe nanolithography

    Science.gov (United States)

    Knoll, A. W.; Zientek, M.; Cheong, L. L.; Rawlings, C.; Paul, P.; Holzner, F.; Hedrick, J. L.; Coady, D. J.; Allen, R.; Dürig, U.

    2014-03-01

    Thermal Scanning Probe Lithography (tSPL) is an AFM based patterning technique, which uses heated tips to locally evaporate organic resists such as molecular glasses [1] or thermally sensitive polymers.[2][3] Organic resists offer the versatility of the lithography process known from the CMOS environment and simultaneously ensure a highly stable and low wear tip-sample contact due to the soft nature of the resists. Patterning quality is excellent up to a resolution of sub 15 nm,[1] at linear speeds of up to 20 mm/s and pixel rates of up to 500 kHz.[4] The patterning depth is proportional to the applied force which allows for the creation of 3-D profiles in a single patterning run.[2] In addition, non-destructive imaging can be done at pixel rates of more than 500 kHz.[4] If the thermal stimulus for writing the pattern is switched off the same tip can be used to record the written topography with Angstrom depth resolution. We utilize this unique feature of SPL to implement an efficient control system for reliable patterning at high speed and high resolution. We combine the writing and imaging process in a single raster scan of the surface. In this closed loop lithography (CLL) approach, we use the acquired data to optimize the writing parameters on the fly. Excellent control is in particular important for an accurate reproduction of complex 3D patterns. These novel patterning capabilities are equally important for a high quality transfer of two-dimensional patterns into the underlying substrate. We utilize an only 3-4 nm thick SiOx hardmask to amplify the 8±0.5 nm deep patterns created by tSPL into a 50 nm thick transfer polymer. The structures in the transfer polymer can be used to create metallic lines by a lift-off process or to further process the pattern into the substrate. Here we demonstrate the fabrication of 27 nm wide lines and trenches 60 nm deep into the Silicon substrate.[5] In addition, the combined read and write approach ensures that the lateral

  15. High-resolution 3D seismic investigation of giant seafloor craters in the Barents Sea

    Science.gov (United States)

    Waage, Malin; Bünz, Stefan; Andreassen, Karin

    2016-04-01

    Multiple giant craters exist on the seafloor in an area of ~ 100 km2 east of Bear Island Trough in the west-central Barents Sea. It has been hypothesized that these craters might have been caused by gas eruptions following the last deglaciation. Gas seepage from the seafloor occurs abundantly in this area. The crater area is still likely to represent one of the largest hot-spots for shallow marine methane release in the arctic. In summer 2015, we acquired high-resolution P-Cable 3D seismic data in this area covering several of the craters and their associated pingo structures. Due to the shallow and hard Triassic bedrock, penetration of the seismic signals is limited to approximately 450 ms bsf. The crater structures are up to 1 km wide and 40 m deep. Pingo structures occur on the rim of some of the craters and are up to 700 m wide and up to 15 m high above the surrounding seafloor. The 3D seismic data reveals faults, fracture networks and weakness zone that resemble pipes or similar vertical, focused fluid-flow structures in the Triassic sedimentary rocks below the craters. The principal orientation of the faults is in a ~ NW-SE direction that coincides with regional faulting from Permo-Triassic extension. The seismic data also show high-amplitude anomalies beneath some of representing shallow gas accumulations that might be the intermediate source of the gas seepage. This might suggest that craters are caused by high pressured gas that migrated from deeper petroleum systems and accumulated in the shallow Triassic rocks during the last glaciation. Previous work indicate that craters of similar size are likely a cause of enormous blow-outs of gas. Our study discusses the formation mechanisms and timing of these potential blow-out craters and whether they formed during the last deglaciation, when this area was likely quite unstable as severe glacial erosion caused localized high isostatic rebound rates here. We also investigate the role of gas hydrates that might

  16. High-frequency ECG

    Science.gov (United States)

    Tragardh, Elin; Schlegel, Todd T.

    2006-01-01

    The standard ECG is by convention limited to 0.05-150 Hz, but higher frequencies are also present in the ECG signal. With high-resolution technology, it is possible to record and analyze these higher frequencies. The highest amplitudes of the high-frequency components are found within the QRS complex. In past years, the term "high frequency", "high fidelity", and "wideband electrocardiography" have been used by several investigators to refer to the process of recording ECGs with an extended bandwidth of up to 1000 Hz. Several investigators have tried to analyze HF-QRS with the hope that additional features seen in the QRS complex would provide information enhancing the diagnostic value of the ECG. The development of computerized ECG-recording devices that made it possible to record ECG signals with high resolution in both time and amplitude, as well as better possibilities to store and process the signals digitally, offered new methods for analysis. Different techniques to extract the HF-QRS have been described. Several bandwidths and filter types have been applied for the extraction as well as different signal-averaging techniques for noise reduction. There is no standard method for acquiring and quantifying HF-QRS. The physiological mechanisms underlying HF-QRS are still not fully understood. One theory is that HF-QRS are related to the conduction velocity and the fragmentation of the depolarization wave in the myocardium. In a three-dimensional model of the ventricles with a fractal conduction system it was shown that high numbers of splitting branches are associated with HF-QRS. In this experiment, it was also shown that the changes seen in HF-QRS in patients with myocardial ischemia might be due to the slowing of the conduction velocity in the region of ischemia. This mechanism has been tested by Watanabe et al by infusing sodium channel blockers into the left anterior descending artery in dogs. In their study, 60 unipolar ECGs were recorded from the entire

  17. Determination of the spatial TDR-sensor characteristics in strong dispersive subsoil using 3D-FEM frequency domain simulations in combination with microwave dielectric spectroscopy

    Science.gov (United States)

    Wagner, Norman; Trinks, Eberhard; Kupfer, Klaus

    2007-04-01

    The spatial sensor characteristics of a 6 cm TDR flat band cable sensor section was simulated with finite element modelling (high frequency structure simulator—HFSS) under certain conditions: (i) in direct contact with the surrounding material (air, water of different salinities, different synthetic and natural soils (sand-silt-clay mixtures)), (ii) with consideration of a defined gap of different size filled with air or water and (iii) the cable sensor pressed at a borehole-wall. The complex dielectric permittivity ɛsstarf(ω, τi) or complex electrical conductivity σsstarf(ω, τi) = iωɛsstarf(ω, τi) of the investigated saturated and unsaturated soils was examined in the frequency range 50 MHz-20 GHz at room temperature and atmospheric pressure with a HP8720D-network analyser. Three soil-specific relaxation processes are assumed to act in the investigated frequency-temperature-pressure range: one primary α-process (main water relaxation) and two secondary (α', β)-processes due to clay-water-ion interactions (bound water relaxation and the Maxwell-Wagner effect). The dielectric relaxation behaviour of every process is described with the use of a simple fractional relaxation model. 3D finite element simulation is performed with a λ/3 based adaptive mesh refinement at a solution frequency of 1 MHz, 10 MHz, 0.1 GHz, 1 GHz and 12.5 GHz. The electromagnetic field distribution, S-parameter and step responses were examined. The simulation adequately reproduces the spatial and temporal electrical and magnetic field distribution. High-lossy soils cause, as a function of increasing gravimetric water content and bulk density, an increase in TDR signal rise time as well as a strong absorption of multiple reflections. An air or water gap works as a quasi-waveguide, i.e. the influence of the surrounding medium is strongly reduced. Appropriate TDR-travel-time distortions can be quantified.

  18. A Fast Full Tensor Gravity computation algorithm for High Resolution 3D Geologic Interpretations

    Science.gov (United States)

    Jayaram, V.; Crain, K.; Keller, G. R.

    2011-12-01

    We present an algorithm to rapidly calculate the vertical gravity and full tensor gravity (FTG) values due to a 3-D geologic model. This algorithm can be implemented on single, multi-core CPU and graphical processing units (GPU) architectures. Our technique is based on the line element approximation with a constant density within each grid cell. This type of parameterization is well suited for high-resolution elevation datasets with grid size typically in the range of 1m to 30m. The large high-resolution data grids in our studies employ a pre-filtered mipmap pyramid type representation for the grid data known as the Geometry clipmap. The clipmap was first introduced by Microsoft Research in 2004 to do fly-through terrain visualization. This method caches nested rectangular extents of down-sampled data layers in the pyramid to create view-dependent calculation scheme. Together with the simple grid structure, this allows the gravity to be computed conveniently on-the-fly, or stored in a highly compressed format. Neither of these capabilities has previously been available. Our approach can perform rapid calculations on large topographies including crustal-scale models derived from complex geologic interpretations. For example, we used a 1KM Sphere model consisting of 105000 cells at 10m resolution with 100000 gravity stations. The line element approach took less than 90 seconds to compute the FTG and vertical gravity on an Intel Core i7 CPU at 3.07 GHz utilizing just its single core. Also, unlike traditional gravity computational algorithms, the line-element approach can calculate gravity effects at locations interior or exterior to the model. The only condition that must be met is the observation point cannot be located directly above the line element. Therefore, we perform a location test and then apply appropriate formulation to those data points. We will present and compare the computational performance of the traditional prism method versus the line element

  19. High Torque Density Transverse Flux Machine without the Need to Use SMC Material for 3D Flux Paths

    DEFF Research Database (Denmark)

    Lu, Kaiyuan; Wu, Weimin

    2015-01-01

    machine topology proposed in this paper, by advantageously utilizing the magnetic flux path provided by an additional rotor, use of laminations that allow 2-D flux paths only will be sufficient to accomplish the required 3-D flux paths. The machine also has a high torque density and is therefore......This paper presents a new transverse flux permanent magnet machine. In a normal transverse flux machine, complicated 3-D flux paths often exist. Such 3-D flux paths would require the use of soft magnetic composites material instead of laminations for construction of the machine stator. In the new...

  20. Data-fusion of high resolution X-ray CT, SEM and EDS for 3D and pseudo-3D chemical and structural characterization of sandstone.

    Science.gov (United States)

    De Boever, Wesley; Derluyn, Hannelore; Van Loo, Denis; Van Hoorebeke, Luc; Cnudde, Veerle

    2015-07-01

    When dealing with the characterization of the structure and composition of natural stones, problems of representativeness and choice of analysis technique almost always occur. Since feature-sizes are typically spread over the nanometer to centimeter range, there is never one single technique that allows a rapid and complete characterization. Over the last few decades, high resolution X-ray CT (μ-CT) has become an invaluable tool for the 3D characterization of many materials, including natural stones. This technique has many important advantages, but there are also some limitations, including a tradeoff between resolution and sample size and a lack of chemical information. For geologists, this chemical information is of importance for the determination of minerals inside samples. We suggest a workflow for the complete chemical and structural characterization of a representative volume of a heterogeneous geological material. This workflow consists of combining information derived from CT scans at different spatial resolutions with information from scanning electron microscopy and energy-dispersive X-ray spectroscopy.

  1. Numerical Calculations of 3-D High-Lift Flows and Comparison with Experiment

    Science.gov (United States)

    Compton, William B, III

    2015-01-01

    Solutions were obtained with the Navier-Stokes CFD code TLNS3D to predict the flow about the NASA Trapezoidal Wing, a high-lift wing composed of three elements: the main-wing element, a deployed leading-edge slat, and a deployed trailing-edge flap. Turbulence was modeled by the Spalart-Allmaras one-equation turbulence model. One case with massive separation was repeated using Menter's two-equation SST (Menter's Shear Stress Transport) k-omega turbulence model in an attempt to improve the agreement with experiment. The investigation was conducted at a free stream Mach number of 0.2, and at angles of attack ranging from 10.004 degrees to 34.858 degrees. The Reynolds number based on the mean aerodynamic chord of the wing was 4.3 x 10 (sup 6). Compared to experiment, the numerical procedure predicted the surface pressures very well at angles of attack in the linear range of the lift. However, computed maximum lift was 5% low. Drag was mainly under predicted. The procedure correctly predicted several well-known trends and features of high-lift flows, such as off-body separation. The two turbulence models yielded significantly different solutions for the repeated case.

  2. Development of high vorticity structures in incompressible 3D Euler equations

    CERN Document Server

    Agafontsev, D S; Mailybaev, A A

    2015-01-01

    We perform the systematic numerical study of high vorticity structures that develop in the 3D incompressible Euler equations from generic large-scale initial conditions. We observe that a multitude of high vorticity structures appear in the form of thin vorticity sheets (pancakes). Our analysis reveals the self-similarity of the pancakes evolution, which is governed by two different exponents $e^{-t/T_{\\ell}}$ and $e^{t/T_{\\omega}}$ describing compression in the transverse direction and the vorticity growth respectively, with the universal ratio $T_{\\ell}/T_{\\omega} \\approx 2/3$. We relate development of these structures to the gradual formation of the Kolmogorov energy spectrum $E_{k}\\propto\\, k^{-5/3}$, which we observe in a fully inviscid system. With the spectral analysis we demonstrate that the energy transfer to small scales is performed through the pancake structures, which accumulate in the Kolmogorov interval of scales and evolve according to the scaling law $\\omega_{\\max} \\propto \\ell^{-2/3}$ for th...

  3. Recipe for High Moment Materials with Rare-earth and 3d Transition Metal Composites.

    Science.gov (United States)

    Autieri, Carmine; Kumar, P Anil; Walecki, Dirk; Webers, Samira; Gubbins, Mark A; Wende, Heiko; Sanyal, Biplab

    2016-01-01

    Materials with high volume magnetization are perpetually needed for the generation of sufficiently large magnetic fields by writer pole of magnetic hard disks, especially for achieving increased areal density in storage media. In search of suitable materials combinations for this purpose, we have employed density functional theory to predict the magnetic coupling between iron and gadolinium layers separated by one to several monolayers of 3d transition metals (Sc-Zn). We demonstrate that it is possible to find ferromagnetic coupling for many of them and in particular for the early transition metals giving rise to high moment. Cr and Mn are the only elements able to produce a significant ferromagnetic coupling for thicker spacer layers. We also present experimental results on two trilayer systems Fe/Sc/Gd and Fe/Mn/Gd. From the experiments, we confirm a ferromagnetic coupling between Fe and Gd across a 3 monolayers Sc spacer or a Mn spacer thicker than 1 monolayer. In addition, we observe a peculiar dependence of Fe/Gd magnetic coupling on the Mn spacer thickness. PMID:27381456

  4. 3D modeling of GJ1214b's atmosphere: formation of inhomogeneous high clouds and observational implications

    CERN Document Server

    Charnay, Benjamin; Misra, Amit; Leconte, Jérémy; Arney, Giada

    2015-01-01

    The warm sub-Neptune GJ1214b has a featureless transit spectrum which may be due to the presence of high and thick clouds or haze. Here, we simulate the atmosphere of GJ1214b with a 3D General Circulation Model for cloudy hydrogen-dominated atmospheres, including cloud radiative effects. We show that the atmospheric circulation is strong enough to transport micrometric cloud particles to the upper atmosphere and generally leads to a minimum of cloud at the equator. By scattering stellar light, clouds increase the planetary albedo to 0.4-0.6 and cool the atmosphere below 1 mbar. However, the heating by ZnS clouds leads to the formation of a stratospheric thermal inversion above 10 mbar, with temperatures potentially high enough on the dayside to evaporate KCl clouds. We show that flat transit spectra consistent with HST observations are possible if cloud particle radii are around 0.5 micron, and that such clouds should be optically thin at wavelengths > 3 microns. Using simulated cloudy atmospheres that fit th...

  5. Recipe for High Moment Materials with Rare-earth and 3d Transition Metal Composites

    Science.gov (United States)

    Autieri, Carmine; Kumar, P. Anil; Walecki, Dirk; Webers, Samira; Gubbins, Mark A.; Wende, Heiko; Sanyal, Biplab

    2016-01-01

    Materials with high volume magnetization are perpetually needed for the generation of sufficiently large magnetic fields by writer pole of magnetic hard disks, especially for achieving increased areal density in storage media. In search of suitable materials combinations for this purpose, we have employed density functional theory to predict the magnetic coupling between iron and gadolinium layers separated by one to several monolayers of 3d transition metals (Sc-Zn). We demonstrate that it is possible to find ferromagnetic coupling for many of them and in particular for the early transition metals giving rise to high moment. Cr and Mn are the only elements able to produce a significant ferromagnetic coupling for thicker spacer layers. We also present experimental results on two trilayer systems Fe/Sc/Gd and Fe/Mn/Gd. From the experiments, we confirm a ferromagnetic coupling between Fe and Gd across a 3 monolayers Sc spacer or a Mn spacer thicker than 1 monolayer. In addition, we observe a peculiar dependence of Fe/Gd magnetic coupling on the Mn spacer thickness. PMID:27381456

  6. High-resolution, real-time simultaneous 3D surface geometry and temperature measurement.

    Science.gov (United States)

    An, Yatong; Zhang, Song

    2016-06-27

    This paper presents a method to simultaneously measure three-dimensional (3D) surface geometry and temperature in real time. Specifically, we developed 1) a holistic approach to calibrate both a structured light system and a thermal camera under exactly the same world coordinate system even though these two sensors do not share the same wavelength; and 2) a computational framework to determine the sub-pixel corresponding temperature for each 3D point as well as discard those occluded points. Since the thermal 2D imaging and 3D visible imaging systems do not share the same spectrum of light, they can perform sensing simultaneously in real time: we developed a hardware system that can achieve real-time 3D geometry and temperature measurement at 26 Hz with 768 × 960 points per frame. PMID:27410608

  7. High-Resolution Visual 3D Recontructions for Rapid Archaeological Characterization

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The final output will be geotiffs and a custom 3D texture model format that allows for dynamic level-of-detail rendering. The work discussed in the proposal will...

  8. Airborne LIDAR and high resolution satellite data for rapid 3D feature extraction

    Science.gov (United States)

    Jawak, S. D.; Panditrao, S. N.; Luis, A. J.

    2014-11-01

    This work uses the canopy height model (CHM) based workflow for individual tree crown delineation and 3D feature extraction approach (Overwatch Geospatial's proprietary algorithm) for building feature delineation from high-density light detection and ranging (LiDAR) point cloud data in an urban environment and evaluates its accuracy by using very high-resolution panchromatic (PAN) (spatial) and 8-band (multispectral) WorldView-2 (WV-2) imagery. LiDAR point cloud data over San Francisco, California, USA, recorded in June 2010, was used to detect tree and building features by classifying point elevation values. The workflow employed includes resampling of LiDAR point cloud to generate a raster surface or digital terrain model (DTM), generation of a hill-shade image and an intensity image, extraction of digital surface model, generation of bare earth digital elevation model (DEM) and extraction of tree and building features. First, the optical WV-2 data and the LiDAR intensity image were co-registered using ground control points (GCPs). The WV-2 rational polynomial coefficients model (RPC) was executed in ERDAS Leica Photogrammetry Suite (LPS) using supplementary *.RPB file. In the second stage, ortho-rectification was carried out using ERDAS LPS by incorporating well-distributed GCPs. The root mean square error (RMSE) for the WV-2 was estimated to be 0.25 m by using more than 10 well-distributed GCPs. In the second stage, we generated the bare earth DEM from LiDAR point cloud data. In most of the cases, bare earth DEM does not represent true ground elevation. Hence, the model was edited to get the most accurate DEM/ DTM possible and normalized the LiDAR point cloud data based on DTM in order to reduce the effect of undulating terrain. We normalized the vegetation point cloud values by subtracting the ground points (DEM) from the LiDAR point cloud. A normalized digital surface model (nDSM) or CHM was calculated from the LiDAR data by subtracting the DEM from the DSM

  9. Extension and application of the reactor dynamics code DYN3D for Block-type High Temperature Reactors

    International Nuclear Information System (INIS)

    The reactor code DYN3D was developed at the Helmholtz-Zentrum Dresden-Rossendorf to study steady state and transient behavior of Light Water Reactors. Concerning the neutronics part, the multigroup diffusion or SP3 transport equation based on nodal expansion methods is solved both for hexagonal and square fuel element geometry. To deal with Block-type High Temperature Reactor cores DYN3D was extended to a version DYN3D-HTR. A 3D heat conduction model was introduced to include 3D effects of heat transfer and heat conduction and the detailed structure of the fuel element. Homogenized neutronic cross sections were generated by applying a Monte Carlo approach with resolution of each individual TRISO fuel particle. Results of coupled steady state and transient calculations with 12 energy groups are presented. Transient case studies are control rod insertion, a change of the inlet coolant temperature and a change of the coolant gas mass flow rate. It is shown that DYN3D-HTR is an appropriate code system to simulate steady states and short time transients. Furthermore the necessity of the 3D heat conduction model is demonstrated

  10. High-Efficiency Solar-Powered 3-D Printers for Sustainable Development

    OpenAIRE

    Jephias Gwamuri; Dhiogo Franco; Khalid Y. Khan; Lucia Gauchia; Joshua M. Pearce

    2016-01-01

    The release of the open source 3-D printer known as the RepRap (a self-Replicating Rapid prototyper) resulted in the potential for distributed manufacturing of products for significantly lower costs than conventional manufacturing. This development, coupled with open source-appropriate technology (OSAT), has enabled the opportunity for 3-D printers to be used for sustainable development. In this context, OSAT provides the opportunity to modify and improve the physical designs of their printer...

  11. EUV magnetic-dipole lines from highly-charged high-Z ions with an open 3d shell

    CERN Document Server

    Osin, D; Reader, J; Ralchenko, Yu

    2012-01-01

    The electron beam ion trap (EBIT) at the National Institute of Standards and Technology was used to produce highly-charged ions of hafnium, tantalum and gold with an open 3d shell. The extreme-ultraviolet (EUV) spectra from these ions were recorded with a flat-field grazing-incidence spectrometer in the wavelength range of 4.5 nm to 25 nm. A total of 133 new spectral lines, primarily due to magnetic-dipole transitions within the ground-state $3d^n$ configurations of the Co-like to K-like ions, were identified by comparing energy-dependent experimental spectra with a detailed collisional-radiative modeling of the EBIT plasma.

  12. Precise 3D printing of micro/nanostructures using highly conductive carbon nanotube-thiol-acrylate composites

    Science.gov (United States)

    Liu, Y.; Xiong, W.; Jiang, L. J.; Zhou, Y. S.; Lu, Y. F.

    2016-04-01

    Two-photon polymerization (TPP) is of increasing interest due to its unique combination of truly three-dimensional (3D) fabrication capability and ultrahigh spatial resolution of ~40 nm. However, the stringent requirements of non-linear resins seriously limit the material functionality of 3D printing via TPP. Precise fabrication of 3D micro/nanostructures with multi-functionalities such as high electrical conductivity and mechanical strength is still a long-standing challenge. In this work, TPP fabrication of arbitrary 3D micro/nanostructures using multi-walled carbon nanotube (MWNT)-thiolacrylate (MTA) composite resins has been developed. Up to 0.2 wt% MWNTs have been incorporated into thiol-acrylate resins to form highly stable and uniform composite photoresists without obvious degradation for one week at room temperature. Various functional 3D micro/nanostructures including woodpiles, micro-coils, spiral-like photonic crystals, suspended micro-bridges, micro-gears and complex micro-cars have been successfully fabricated. The MTA composite resin offers significant enhancements in electrical conductivity and mechanical strength, and on the same time, preserving high optical transmittance and flexibility. Tightly controlled alignment of MWNTs and the strong anisotropy effect were confirmed. Microelectronic devices including capacitors and resistors made of the MTA composite polymer were demonstrated. The 3D micro/nanofabrication using the MTA composite resins enables the precise 3D printing of micro/nanostructures of high electrical conductivity and mechanical strength, which is expected to lead a wide range of device applications, including micro/nano-electromechanical systems (MEMS/NEMS), integrated photonics and 3D electronics.

  13. Benchmarking of 3D space charge codes using direct phase space measurements from photoemission high voltage DC gun

    OpenAIRE

    Bazarov, Ivan V.; Dunham, Bruce M.; Gulliford, Colwyn; Li, Yulin; Liu, Xianghong; Sinclair, Charles K.; Soong, Ken; Hannon, Fay

    2008-01-01

    We present a comparison between space charge calculations and direct measurements of the transverse phase space for space charge dominated electron bunches after a high voltage photoemission DC gun followed by an emittance compensation solenoid magnet. The measurements were performed using a double-slit setup for a set of parameters such as charge per bunch and the solenoid current. The data is compared with detailed simulations using 3D space charge codes GPT and Parmela3D with initial parti...

  14. 3D hybrid-porous carbon derived from carbonization of metal organic frameworks for high performance supercapacitors

    Science.gov (United States)

    Bao, Weizhai; Mondal, Anjon Kumar; Xu, Jing; Wang, Chengyin; Su, Dawei; Wang, Guoxiu

    2016-09-01

    We report a rational design and synthesis of 3D hybrid-porous carbon with a hierarchical pore architecture for high performance supercapacitors. It contains micropores (3D hybrid-porous carbon demonstrates a specific capacitance of 332 F g-1 at a constant charge/discharge current of 500 mA g-1. The supercapacitors can endure more than 10,000 cycles without degradation of capacitance.

  15. Detection of 3D tree root systems using high resolution ground penetration radar

    Science.gov (United States)

    Altdorff, D.; Honds, M.; Botschek, J.; Van Der Kruk, J.

    2014-12-01

    Knowledge of root systems and its distribution are important for biomass estimation as well as for the prevention of subsurface distribution network damages. Ground penetration radar (GPR) is a promising technique that enables a non-invasive imaging of tree roots. Due to the polarisation-dependent reflection coefficients and complicated three-dimensional root structure, accurate measurements with perpendicularly polarized antennas are needed. In this study, we show GPR data from two planes and one chestnut at two locations with different soil conditions. Perpendicular 10 x 10 cm grid measurements were made with a shielded 250 MHz antenna in combination with a high precision self-tracking laser theodolite that provides geo-referenced traces with a spatial resolution of ~ 2 cm. After selecting potential root hyperbolas within the perpendicular GPR profiles, the corresponding three-dimensional coordinates were extracted and visualized in planar view to reveal any linear structure that indicates a possible tree root. The coordinates of the selected linear structures were projected back to the surface by means of the laser-theodolite to indicate the locations for groundtruthing. Additionally, we interpolated the measured data into a 3D cube where time slices confirmed the locations of linear reflection events. We validated the indicated predictions by excavation of the soil with a suction dredge. Subsequent georeferencing of the true root distribution and comparison with the selected linear events showed that the approach was able to identify the precise position of roots with a diameter between 3 and 10 cm and a depth of up to 70 cm. However, not all linear events were roots; also mouse channels were found in these depths, since they also generate GPR hyperbolas aligned in linear structures. Roots at a second location at depths of 1 to 1.20 m did not generate identifiable hyperboles, which was probably due to an increased electrical conductivity below 86 cm depth. The

  16. Study of CT-based positron range correction in high resolution 3D PET imaging

    Energy Technology Data Exchange (ETDEWEB)

    Cal-Gonzalez, J., E-mail: jacobo@nuclear.fis.ucm.es [Grupo de Fisica Nuclear, Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Herraiz, J.L. [Grupo de Fisica Nuclear, Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Espana, S. [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Vicente, E. [Grupo de Fisica Nuclear, Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Instituto de Estructura de la Materia, Consejo Superior de Investigaciones Cientificas (CSIC), Madrid (Spain); Herranz, E. [Grupo de Fisica Nuclear, Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Desco, M. [Unidad de Medicina y Cirugia Experimental, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Vaquero, J.J. [Dpto. de Bioingenieria e Ingenieria Espacial, Universidad Carlos III, Madrid (Spain); Udias, J.M. [Grupo de Fisica Nuclear, Dpto. Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain)

    2011-08-21

    Positron range limits the spatial resolution of PET images and has a different effect for different isotopes and positron propagation materials. Therefore it is important to consider it during image reconstruction, in order to obtain optimal image quality. Positron range distributions for most common isotopes used in PET in different materials were computed using the Monte Carlo simulations with PeneloPET. The range profiles were introduced into the 3D OSEM image reconstruction software FIRST and employed to blur the image either in the forward projection or in the forward and backward projection. The blurring introduced takes into account the different materials in which the positron propagates. Information on these materials may be obtained, for instance, from a segmentation of a CT image. The results of introducing positron blurring in both forward and backward projection operations was compared to using it only during forward projection. Further, the effect of different shapes of positron range profile in the quality of the reconstructed images with positron range correction was studied. For high positron energy isotopes, the reconstructed images show significant improvement in spatial resolution when positron range is taken into account during reconstruction, compared to reconstructions without positron range modeling.

  17. In vivo high-resolution 3D photoacoustic imaging of superficial vascular anatomy

    International Nuclear Information System (INIS)

    The application of a photoacoustic imaging instrument based upon a Fabry-Perot polymer film ultrasound sensor to imaging the superficial vasculature is described. This approach provides a backward mode-sensing configuration that has the potential to overcome the limitations of current piezoelectric based detection systems used in superficial photoacoustic imaging. The system has been evaluated by obtaining non-invasive images of the vasculature in human and mouse skin as well as mouse models of human colorectal tumours. These studies showed that the system can provide high-resolution 3D images of vascular structures to depths of up to 5 mm. It is considered that this type of instrument may find a role in the clinical assessment of conditions characterized by changes in the vasculature such as skin tumours and superficial soft tissue damage due to burns, wounds or ulceration. It may also find application in the characterization of small animal cancer models where it is important to follow the tumour vasculature over time in order to study its development and/or response to therapy.

  18. Efficient Simplification Methods for Generating High Quality LODs of 3D Meshes

    Institute of Scientific and Technical Information of China (English)

    Muhammad Hussain

    2009-01-01

    Two simplification algorithms are proposed for automatic decimation of polygonal models, and for generating their LODs. Each algorithm orders vertices according to their priority values and then removes them iteratively. For setting the priority value of each vertex, exploiting normal field of its one-ring neighborhood, we introduce a new measure of geometric fidelity that reflects well the local geometric features of the vertex. After a vertex is selected, using other measures of geometric distortion that are based on normal field deviation and distance measure, it is decided which of the edges incident on the vertex is to be collapsed for removing it. The collapsed edge is substituted with a new vertex whose position is found by minimizing the local quadric error measure. A comparison with the state-of-the-art algorithms reveals that the proposed algorithms are simple to implement, are computationally more efficient, generate LODs with better quality, and preserve salient features even after drastic simplification. The methods are useful for applications such as 3D computer games, virtual reality, where focus is on fast running time, reduced memory overhead, and high quality LODs.

  19. Enhanced high dynamic range 3D shape measurement based on generalized phase-shifting algorithm

    CERN Document Server

    Wang, Minmin; Zhou, Canlin; Zhang, Chaorui; Si, Shuchun; Li, Hui; Lei, Zhenkun; Li, YanJie

    2016-01-01

    It is a challenge for Phase Measurement Profilometry (PMP) to measure objects with a large range of reflectivity variation across the surface. Saturated or dark pixels in the deformed fringe patterns captured by the camera will lead to phase fluctuations and errors. Jiang et al. proposed a high dynamic range real-time 3D shape measurement method without changing camera exposures. Three inverted phase-shifted fringe patterns are used to complement three regular phase-shifted fringe patterns for phase retrieval when any of the regular fringe patterns are saturated. But Jiang's method still has some drawbacks: (1) The phases in saturated pixels are respectively estimated by different formulas for different cases. It is shortage of an universal formula; (2) it cannot be extended to four-step phase-shifting algorithm because inverted fringe patterns are the repetition of regular fringe patterns; (3) only three unsaturated intensity values at every pixel of fringe patterns are chosen for phase demodulation, lying i...

  20. Interlayer Simplified Depth Coding for Quality Scalability on 3D High Efficiency Video Coding

    Directory of Open Access Journals (Sweden)

    Mengmeng Zhang

    2014-01-01

    Full Text Available A quality scalable extension design is proposed for the upcoming 3D video on the emerging standard for High Efficiency Video Coding (HEVC. A novel interlayer simplified depth coding (SDC prediction tool is added to reduce the amount of bits for depth maps representation by exploiting the correlation between coding layers. To further improve the coding performance, the coded prediction quadtree and texture data from corresponding SDC-coded blocks in the base layer can be used in interlayer simplified depth coding. In the proposed design, the multiloop decoder solution is also extended into the proposed scalable scenario for texture views and depth maps, and will be achieved by the interlayer texture prediction method. The experimental results indicate that the average Bjøntegaard Delta bitrate decrease of 54.4% can be gained in interlayer simplified depth coding prediction tool on multiloop decoder solution compared with simulcast. Consequently, significant rate savings confirm that the proposed method achieves better performance.

  1. Nonlinear 3-D simulation of high-intensity focused ultrasound therapy in the kidney

    CERN Document Server

    Suomi, Visa; Treeby, Bradley; Cleveland, Robin

    2016-01-01

    Kidney cancer is a severe disease which can be treated non-invasively using high-intensity focused ultrasound (HIFU) therapy. However, tissue in front of the transducer and the deep location of kidney can cause significant losses to the efficiency of the treatment. The effect of attenuation, refraction and reflection due to different tissue types on HIFU therapy of the kidney was studied using a nonlinear ultrasound simulation model. The geometry of the tissue was derived from a computed tomography (CT) dataset of a patient which had been segmented for water, bone, soft tissue, fat and kidney. The combined effect of inhomogeneous attenuation and sound-speed was found to result in an 11.0 dB drop in spatial peak-temporal average (SPTA) intensity in the kidney compared to pure water. The simulation without refraction effects showed a 6.3 dB decrease indicating that both attenuation and refraction contribute to the loss in focal intensity. The losses due to reflections at soft tissue interfaces were less than 0....

  2. 3D interconnect architecture for high-bandwidth massively paralleled imager

    International Nuclear Information System (INIS)

    The proton radiography group at LANL is developing a fast (5x106 frames/s or 5 megaframe/s) multi-frame imager for use in dynamic radiographic experiments with high-energy protons. The mega-pixel imager will acquire and process a burst of 32 frames captured at inter-frame time ∼200 ns. Real time signal processing and storage requirements for entire frames, of rapidly acquired pixels impose severe demands on the space available for the electronics in a standard monolithic approach. As such, a 3D arrangement of detector and circuit elements is under development. In this scheme, the readout integrated circuits (ROICs) are stacked vertically (like playing cards) into a cube configuration. Another die, a fully depleted pixel photo-diode focal plane array (FPA), is bump bonded to one of the edge surfaces formed by the resulting ROIC cube. Recently, an assembly of the proof-of-principle test cube and sensor has been completed

  3. 3D interconnect architecture for high-bandwidth massively paralleled imager

    Energy Technology Data Exchange (ETDEWEB)

    Kwiatkowski, K. E-mail: krisk@lanl.gov; Lyke, J.C.; Wojnarowski, R.J.; Beche, J.-F.; Fillion, R.; Kapusta, C.; Millaud, J.; Saia, R.; Wilke, M.D

    2003-08-21

    The proton radiography group at LANL is developing a fast (5x10{sup 6} frames/s or 5 megaframe/s) multi-frame imager for use in dynamic radiographic experiments with high-energy protons. The mega-pixel imager will acquire and process a burst of 32 frames captured at inter-frame time {approx}200 ns. Real time signal processing and storage requirements for entire frames, of rapidly acquired pixels impose severe demands on the space available for the electronics in a standard monolithic approach. As such, a 3D arrangement of detector and circuit elements is under development. In this scheme, the readout integrated circuits (ROICs) are stacked vertically (like playing cards) into a cube configuration. Another die, a fully depleted pixel photo-diode focal plane array (FPA), is bump bonded to one of the edge surfaces formed by the resulting ROIC cube. Recently, an assembly of the proof-of-principle test cube and sensor has been completed.

  4. Carbon Nanofiber/3D Nanoporous Silicon Hybrids as High Capacity Lithium Storage Materials.

    Science.gov (United States)

    Park, Hyeong-Il; Sohn, Myungbeom; Kim, Dae Sik; Park, Cheolho; Choi, Jeong-Hee; Kim, Hansu

    2016-04-21

    Carbon nanofiber (CNF)/3D nanoporous (3DNP) Si hybrid materials were prepared by chemical etching of melt-spun Si/Al-Cu-Fe alloy nanocomposites, followed by carbonization using a pitch. CNFs were successfully grown on the surface of 3DNP Si particles using residual Fe impurities after acidic etching, which acted as a catalyst for the growth of CNFs. The resulting CNF/3DNP Si hybrid materials showed an enhanced cycle performance up to 100 cycles compared to that of the pristine Si/Al-Cu-Fe alloy nanocomposite as well as that of bare 3DNP Si particles. These results indicate that CNFs and the carbon coating layer have a beneficial effect on the capacity retention characteristics of 3DNP Si particles by providing continuous electron-conduction pathways in the electrode during cycling. The approach presented here provides another way to improve the electrochemical performances of porous Si-based high capacity anode materials for lithium-ion batteries. PMID:26970098

  5. Electrochemical reduction approach-based 3D graphene/Ni(OH)2 electrode for high-performance supercapacitors

    International Nuclear Information System (INIS)

    Highlights: • 3D graphene foam is synthesized by a simple electrochemical reduction method. • The 3D graphene/Ni(OH)2 composite is used as a monolithic free-standing electrode material. • The 3D conductive graphene network improves the contact between electrode and electrolyte. • Compositing graphene with Ni(OH)2 sheets take full advantage of the synergistic effects. • Results show that the as-synthesized products have good electrochemical property. - Abstract: Using a simple electrochemical reduction approach, we have produced three-dimensional (3D) graphene foam having high conductivity and well-defined macroporous structure. Through a hydrothermal process, Ni(OH)2 sheets are grown in-situ onto the graphene surface. This monolithic 3D graphene/Ni(OH)2 composite is used as the free-standing electrode for supercapacitor application; it shows a high specific capacitance of 183.1 F g−1 (based on the total mass of the electrode), along with excellent rate capability and cycle performance. The asymmetric supercapacitor based on the 3D graphene/Ni(OH)2 as a positive electrode and active carbon (AC) as a negative electrode is also assembled and it exhibits a specific capacitance of 148.3 F g−1 at 0.56 A g−1 and a high energy density of 52.7 W h kg−1 at a power density of 444.4 W kg−1. Moreover, 3D graphene/Ni(OH)2//AC has a good cycle stability (87.9% capacitance retention after 1000 cycles), making it promising as one of the most attractive candidates for electrochemical energy storage. This excellent electrochemical performance results from the multiplexed 3D graphene network facilitating electron transport; the interlaced Ni(OH)2 sheets shorten ion diffusion paths and facilitate the rapid migration of electrolyte ions

  6. 3D AGENT methodology validation for prismatic high-temperature gas-cooled reactor

    International Nuclear Information System (INIS)

    The Generation IV of nuclear reactors includes as highly competitive the design of a Very High Temperature Reactor (VHTR). This type of reactors can be of a prismatic block, or pebble-bed type. An example of a prismatic block nuclear reactor is the High Temperature Test Reactor (HTTR) operated by Japan Atomic Energy Agency; the reactor reached its full power of 30 MWth for the first time in 1999. The primary coolant is helium at the pressure of ∼4 MPa, with inlet-outlet temperatures of 395°C and 850 – 950°C, respectively. The fuel is 6% enriched uranium, and the moderator is made of graphite. Using the literature available data, a comprehensive validation study is performed to benchmark and assess the AGENT (Arbitrary GEometry Neutron Transport) methodology capabilities in predicting and capturing reactor physics details affected by double heterogeneity of the fuel. Using AGENT with explicit modeling of the fuel double heterogeneity, the HTTR neutronics parameters are compared to NEWT and KENO VI, as well as to experimental data as found in literature. Detailed analysis of spatial steady-state reaction rates and flux spatial maps are provided. The AGENT methodology is based on the method of characteristics and the only one in the world as applied to reactor systems, the R-function based reactor solid modeler, in providing an accurate deterministic solution for 3D steady-state reactor physics. The R-functions modeler presents no limits to reactor geometry and materials types with their distributions. (author)

  7. Exploring the Potential of Aerial Photogrammetry for 3d Modelling of High-Alpine Environments

    Science.gov (United States)

    Legat, K.; Moe, K.; Poli, D.; Bollmannb, E.

    2016-03-01

    cameras of Microsoft's UltraCam series and the in-house processing chain centred on the Dense-Image-Matching (DIM) software SURE by nFrames. This paper reports the work carried out at AVT for the surface- and terrain modelling of several high-alpine areas using DIM- and ALS-based approaches. A special focus is dedicated to the influence of terrain morphology, flight planning, GNSS/IMU measurements, and ground-control distribution in the georeferencing process on the data quality. Based on the very promising results, some general recommendations for aerial photogrammetry processing in high-alpine areas are made to achieve best possible accuracy of the final 3D-, 2.5D- and 2D products.

  8. CellSegm - a MATLAB toolbox for high-throughput 3D cell segmentation.

    Science.gov (United States)

    Hodneland, Erlend; Kögel, Tanja; Frei, Dominik Michael; Gerdes, Hans-Hermann; Lundervold, Arvid

    2013-08-09

    : The application of fluorescence microscopy in cell biology often generates a huge amount of imaging data. Automated whole cell segmentation of such data enables the detection and analysis of individual cells, where a manual delineation is often time consuming, or practically not feasible. Furthermore, compared to manual analysis, automation normally has a higher degree of reproducibility. CellSegm, the software presented in this work, is a Matlab based command line software toolbox providing an automated whole cell segmentation of images showing surface stained cells, acquired by fluorescence microscopy. It has options for both fully automated and semi-automated cell segmentation. Major algorithmic steps are: (i) smoothing, (ii) Hessian-based ridge enhancement, (iii) marker-controlled watershed segmentation, and (iv) feature-based classfication of cell candidates. Using a wide selection of image recordings and code snippets, we demonstrate that CellSegm has the ability to detect various types of surface stained cells in 3D. After detection and outlining of individual cells, the cell candidates can be subject to software based analysis, specified and programmed by the end-user, or they can be analyzed by other software tools. A segmentation of tissue samples with appropriate characteristics is also shown to be resolvable in CellSegm. The command-line interface of CellSegm facilitates scripting of the separate tools, all implemented in Matlab, offering a high degree of flexibility and tailored workflows for the end-user. The modularity and scripting capabilities of CellSegm enable automated workflows and quantitative analysis of microscopic data, suited for high-throughput image based screening.

  9. Gold@silver bimetal nanoparticles/pyramidal silicon 3D substrate with high reproducibility for high-performance SERS

    Science.gov (United States)

    Zhang, Chao; Jiang, Shou Zhen; Yang, Cheng; Li, Chong Hui; Huo, Yan Yan; Liu, Xiao Yun; Liu, Ai Hua; Wei, Qin; Gao, Sai Sai; Gao, Xing Guo; Man, Bao Yuan

    2016-05-01

    A novel and efficient surface enhanced Raman scattering (SERS) substrate has been presented based on Gold@silver/pyramidal silicon 3D substrate (Au@Ag/3D-Si). By combining the SERS activity of Ag, the chemical stability of Au and the large field enhancement of 3D-Si, the Au@Ag/3D-Si substrate possesses perfect sensitivity, homogeneity, reproducibility and chemical stability. Using R6G as probe molecule, the SERS results imply that the Au@Ag/3D-Si substrate is superior to the 3D-Si, Ag/3D-Si and Au/3D-Si substrate. We also confirmed these excellent behaviors in theory via a commercial COMSOL software. The corresponding experimental and theoretical results indicate that our proposed Au@Ag/3D-Si substrate is expected to develop new opportunities for label-free SERS detections in biological sensors, biomedical diagnostics and food safety.

  10. Gold@silver bimetal nanoparticles/pyramidal silicon 3D substrate with high reproducibility for high-performance SERS

    Science.gov (United States)

    Zhang, Chao; Jiang, Shou Zhen; Yang, Cheng; Li, Chong Hui; Huo, Yan Yan; Liu, Xiao Yun; Liu, Ai Hua; Wei, Qin; Gao, Sai Sai; Gao, Xing Guo; Man, Bao Yuan

    2016-01-01

    A novel and efficient surface enhanced Raman scattering (SERS) substrate has been presented based on Gold@silver/pyramidal silicon 3D substrate (Au@Ag/3D-Si). By combining the SERS activity of Ag, the chemical stability of Au and the large field enhancement of 3D-Si, the Au@Ag/3D-Si substrate possesses perfect sensitivity, homogeneity, reproducibility and chemical stability. Using R6G as probe molecule, the SERS results imply that the Au@Ag/3D-Si substrate is superior to the 3D-Si, Ag/3D-Si and Au/3D-Si substrate. We also confirmed these excellent behaviors in theory via a commercial COMSOL software. The corresponding experimental and theoretical results indicate that our proposed Au@Ag/3D-Si substrate is expected to develop new opportunities for label-free SERS detections in biological sensors, biomedical diagnostics and food safety. PMID:27143507

  11. Synthesis on structure and properties of zinc nanocrystal in high ordered 3D nanostructures

    International Nuclear Information System (INIS)

    The wet impregnation method was employed to prepare ZnO encapsulated in mesoporous silica (ZnO/KIT-6). The prepared ZnO/KIT-6 samples have been studied by X-ray diffraction, transmission electron microscope, and nitrogen adsorption–desorption isotherm. The low angle powder XRD patterns of Calcined ZnO/KIT-6 materials showed a phase that can be indexed to cubic Ia3d. Tem images revealed well ordered cubic 3D nanoporous chennels. The ZnO encapsulated in KIT-6 can be used as light-emitting diodes and ultraviolet nanolasers

  12. 3D-image-guided high-dose-rate intracavitary brachytherapy for salvage treatment of locally persistent nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    To evaluate the therapeutic benefit of 3D-image-guided high-dose-rate intracavitary brachytherapy (3D-image-guided HDR-BT) used as a salvage treatment of intensity modulated radiation therapy (IMRT) in patients with locally persistent nasopharyngeal carcinoma (NPC). Thirty-two patients with locally persistent NPC after full dose of IMRT were evaluated retrospectively. 3D-image-guided HDR-BT treatment plan was performed on a 3D treatment planning system (PLATO BPS 14.2). The median dose of 16 Gy was delivered to the 100% isodose line of the Gross Tumor Volume. The whole procedure was well tolerated under local anesthesia. The actuarial 5-y local control rate for 3D-image-guided HDR-BT was 93.8%, patients with early-T stage at initial diagnosis had 100% local control rate. The 5-y actuarial progression-free survival and distant metastasis-free survival rate were 78.1%, 87.5%. One patient developed and died of lung metastases. The 5-y actuarial overall survival rate was 96.9%. Our results showed that 3D-image-guided HDR-BT would provide excellent local control as a salvage therapeutic modality to IMRT for patients with locally persistent disease at initial diagnosis of early-T stage NPC

  13. Three-dimensional (3-D) thermal investigation below high Alpine topography

    Science.gov (United States)

    Kohl, T.; Signorelli, S.; Rybach, L.

    2001-11-01

    The characteristics of severe topography in active mountain belts represent a special challenge for the evaluation of subsurface temperatures. These conditions require in particular a proper treatment of possible thermally relevant mechanisms. In the present analysis temperature data from depths of up to 1.5 km are investigated which have been collected at the intermediate "point-of-attack" in the framework of the new Alpine transverse (NEAT) project in central Switzerland for the construction of a 57 km long base tunnel. Specially designed temperature measurements were used in a 800 m deep shaft and along a 1200 m long access adit. Additional thermal information was provided by temperature logs from two nearby exploration boreholes and from laboratory measurements of various samples. For a detailed investigation of the temperature data a transient finite element (FE) model has been used which accounts for fluid and mass advection (uplift) as well as for climatic changes. The uplift and exhumation scenario assumed the surface to be in steady-state conditions. Special emphasis was given to structural effects like topography and anisotropy. The 3-D numerical model extends over an area of ˜ 20 km×20 km and includes Alpine high topographic relief with altitudes between 1500 and 3000 m a.s.l. Without modifying petrophysical parameters determined from laboratory measurements, all reliable temperature data could be nearly perfectly fitted by adjusting the two principal thermal boundary conditions at the surface and at the bottom. This study reveals that hydraulic influence is generally negligible at depths below ˜500 m which is in contrast to results from lower-dimensional methods such as 1-D Péclet analyses. Vertical heat flow variations are rather due to topographic than to hydraulic impact. Sensitivity studies highlight the importance of uplift in the central Swiss Alps and of local ground surface temperature (GST) distribution which both can influence the

  14. A Scheme of 3-D Breakdown-whip Analysis Methodology for High Energy Piping

    International Nuclear Information System (INIS)

    excessive conservatism. It is thought that more accurate and effective system design is possible by making a combination of fluid transient analysis and 3-D structural analysis. The main purpose of this study is to introduce the procedure and method for analyzing 3-dimensional breakdown-whip of high energy piping. This study also shows some results of analyzing the fluid transient loads at the main steam line of APR1400

  15. High-resolution magnetic resonance angiography of the internal carotid artery: 2D vs 3D TOF in stenotic disease

    Energy Technology Data Exchange (ETDEWEB)

    Carriero, A.; Magarelli, N.; Marano, R.; Ambrosini, R.; Bonomo, L. [Department of Radiology, University of Chieti (Italy); Scarabino, T. [IRCCS, S. Giovanni Rotondo, Foggia (Italy); Salvolini, U. [Department of Neuroradiology, University of Ancona (Italy)

    1998-10-01

    The aim of this study was to compare high-resolution 2D TOF with high-resolution 3D TOF in the study of internal carotid artery disease. Sixty-four patients with clinical signs of cerebrovascular insufficiency were studied with a superconductive 1.5 T magnet using two techniques: 2D and 3D TOF. Digital subtraction angiography (DSA) was the gold standard. The 2D TOF technique was performed using the following parameters: TR/TE/FA/MA 49 ms/9 ms/60 /512 x 256; the 3D TOF was performed with the following parameters: TR/TE/FA/MA 50 ms/8 ms/20 /512 x 256. The 2D TOF agreed with DSA in 116 of 128 diagnostic judgments (90 %) and overestimated seven times. The 3D TOF technique agreed with DSA in 125 of 128 diagnostic judgments (97 %) with one overestimation and two underestimations. There was no statistically significant difference (P < 0.05) between the two different techniques. Our study confirms the high reliability of themethodology carried out with the high-resolution 2D and 3D technique. (orig.) (orig.) With 1 fig., 5 refs.

  16. 3D imaging of subducting and fragmenting Indian continental lithosphere beneath southern and central Tibet using body-wave finite-frequency tomography

    Science.gov (United States)

    Liang, Xiaofeng; Chen, Yun; Tian, Xiaobo; Chen, Yongshun John; Ni, James; Gallegos, Andrea; Klemperer, Simon L.; Wang, Minling; Xu, Tao; Sun, Changqing; Si, Shaokun; Lan, Haiqiang; Teng, Jiwen

    2016-06-01

    We perform a finite-frequency tomographic inversion to image 3D velocity structures beneath southern and central Tibet using teleseismic body-wave data recorded by the TIBET-31N passive seismic array as well as waveforms from previous temporary seismic arrays. High-velocity bodies dip ∼40° northward beneath the Himalaya and the Lhasa Terrane. We interpret these high-velocity anomalies as subducting Indian Continental Lithosphere (ICL). The ICL appears to extend further north in central Tibet than in eastern Tibet, reaching 350 km depth at ∼31°N along 85°E but at ∼30°N along 91°E. Low P- and S-wave velocity anomalies extend from the lower crust to ≥180 km depth beneath the Tangra Yum Co Rift, Yadong-Gulu Rift, and the Cona Rift, suggesting that rifting in southern Tibet may involve the entire lithosphere. The anomaly beneath Tangra Yum Co Rift extends down to about 180 km, whereas the anomalies west of the Yadong-Gulu Rift and east of the Cona Rift extend to more than 300 km depth. The low-velocity upper mantle west of the Yadong-Gulu Rift extends furthest north and appears to connect with the extensive upper-mantle low-velocity region beneath central Tibet. Thus the northward-subducting Indian Plate is fragmented along north-south breaks that permit or induce asthenospheric upwellings indistinguishable from the upper mantle of northern Tibet.

  17. Thermal-hydraulic system study of a high pressure, high temperature helium loop using RELAP5-3D code

    International Nuclear Information System (INIS)

    Highlights: ► A thermal-hydraulic system analysis for a high pressure, high temperature helium loop has been investigated. ► The loop belongs to the Helium Loop Karlsruhe (HELOKA) facility, which contains the European Helium Cooled Pebble Beds Test Blanket Module (HCPB TBM) as the test module. ► The loop including all components has been modeled using the system code REALP5-3D, and the main control strategy has been implemented as well. ► With this model, the loop dynamics in conditions relevant for blanket module operation have been demonstrated. - Abstract: The thermal-hydraulic system analysis for the Helium Loop Karlsruhe (HELOKA) facility, a high pressure, high temperature experimental helium loop having the European Helium Cooled Pebble Beds Test Blanket Module (HCPB TBM) as the test module, was investigated. Using the system code REALP5-3D, all components in the loop are modeled as well as the main control strategy. With this model, the loop dynamics in conditions relevant for blanket module operation are simulated and analyzed.

  18. Preparation of 3D nanoporous copper-supported cuprous oxide for high-performance lithium ion battery anodes.

    Science.gov (United States)

    Liu, Dequan; Yang, Zhibo; Wang, Peng; Li, Fei; Wang, Desheng; He, Deyan

    2013-03-01

    Three-dimensional (3D) nanoporous architectures can provide efficient and rapid pathways for Li-ion and electron transport as well as short solid-state diffusion lengths in lithium ion batteries (LIBs). In this work, 3D nanoporous copper-supported cuprous oxide was successfully fabricated by low-cost selective etching of an electron-beam melted Cu(50)Al(50) alloy and subsequent in situ thermal oxidation. The architecture was used as an anode in lithium ion batteries. In the first cycle, the sample delivered an extremely high lithium storage capacity of about 2.35 mA h cm(-2). A high reversible capacity of 1.45 mA h cm(-2) was achieved after 120 cycles. This work develops a promising approach to building reliable 3D nanostructured electrodes for high-performance lithium ion batteries.

  19. 3D frequency modeling of elastic seismic wave propagation via a structured massively parallel direct Helmholtz solver

    Science.gov (United States)

    Wang, S.; De Hoop, M. V.; Xia, J.; Li, X.

    2011-12-01

    We consider the modeling of elastic seismic wave propagation on a rectangular domain via the discretization and solution of the inhomogeneous coupled Helmholtz equation in 3D, by exploiting a parallel multifrontal sparse direct solver equipped with Hierarchically Semi-Separable (HSS) structure to reduce the computational complexity and storage. In particular, we are concerned with solving this equation on a large domain, for a large number of different forcing terms in the context of seismic problems in general, and modeling in particular. We resort to a parsimonious mixed grid finite differences scheme for discretizing the Helmholtz operator and Perfect Matched Layer boundaries, resulting in a non-Hermitian matrix. We make use of a nested dissection based domain decomposition, and introduce an approximate direct solver by developing a parallel HSS matrix compression, factorization, and solution approach. We cast our massive parallelization in the framework of the multifrontal method. The assembly tree is partitioned into local trees and a global tree. The local trees are eliminated independently in each processor, while the global tree is eliminated through massive communication. The solver for the inhomogeneous equation is a parallel hybrid between multifrontal and HSS structure. The computational complexity associated with the factorization is almost linear with the size of the Helmholtz matrix. Our numerical approach can be compared with the spectral element method in 3D seismic applications.

  20. MoS2 Nanosheets Supported on 3D Graphene Aerogel as a Highly Efficient Catalyst for Hydrogen Evolution.

    Science.gov (United States)

    Zhao, Yufei; Xie, Xiuqiang; Zhang, Jinqiang; Liu, Hao; Ahn, Hyo-Jun; Sun, Kening; Wang, Guoxiu

    2015-11-01

    The development of efficient catalysts for electrochemical hydrogen evolution is essential for energy conversion technologies. Molybdenum disulfide (MoS2 ) has emerged as a promising electrocatalyst for hydrogen evolution reaction, and its performance greatly depends on its exposed edge sites and conductivity. Layered MoS2 nanosheets supported on a 3D graphene aerogel network (GA-MoS2 ) exhibit significant catalytic activity in hydrogen evolution. The GA-MoS2 composite displays a unique 3D architecture with large active surface areas, leading to high catalytic performance with low overpotential, high current density, and good stability.

  1. Design, Analysis, and Initial Testing of a Fiber-Optic Shear Gage for 3D, High-Temperature Flows

    OpenAIRE

    Orr, Matthew William

    2004-01-01

    Design, Analysis, and Initial Testing of a Fiber-Optic Shear Gage for 3D, High-Temperature Flows Matthew W. Orr Dr. Joseph A. Schetz, Chairman Aerospace Engineering Abstract This investigation concerns the design, analysis, and initial testing of a new, two-component wall shear gage for 3D, high-temperature flows. This gage is a direct-measuring, non-nulling design with a round head surrounded by a small gap. Two flexure wheels are used to allow small motions of the flo...

  2. Fully Automated One-Step Production of Functional 3D Tumor Spheroids for High-Content Screening.

    Science.gov (United States)

    Monjaret, François; Fernandes, Mathieu; Duchemin-Pelletier, Eve; Argento, Amelie; Degot, Sébastien; Young, Joanne

    2016-04-01

    Adoption of spheroids within high-content screening (HCS) has lagged behind high-throughput screening (HTS) due to issues with running complex assays on large three-dimensional (3D) structures.To enable multiplexed imaging and analysis of spheroids, different cancer cell lines were grown in 3D on micropatterned 96-well plates with automated production of nine uniform spheroids per well. Spheroids achieve diameters of up to 600 µm, and reproducibility was experimentally validated (interwell and interplate CV(diameter) integration of micropatterned spheroid models within fundamental research and drug discovery applications.

  3. Parameter analysis for a high-gain harmonic generation FEL using a recently developed 3D polychromatic code

    CERN Document Server

    Biedron, S G; Yu, L H

    2000-01-01

    One possible design for a fourth-generation light source is the high-gain harmonic generation (HGHG) free-electron laser (FEL). Here, a coherent seed with a wavelength at a subharmonic of the desired output radiation interacts with the electron beam in an energy-modulating section. This energy modulation is then converted into spatial bunching while traversing a dispersive section (a three-dipole chicane). The final step is passage through an undulator tuned to the desired higher harmonic output wavelength. The coherent seed serves to suppress and can be at a much lower subharmonic of the output radiation. Recently, a 3D code that includes multiple frequencies, multiple undulators (both in quantity and/or type), quadrupole magnets, and dipole magnets was developed to easily simulate HGHG. Here, a brief review of the HGHG theory, the code development, the Accelerator Test Facility's (ATF) HGHG FEL experimental parameters, and the parameter analysis from simulations of this specific experiment will be discussed...

  4. Parameter analysis for a high-gain harmonic generation FEL using a recently developed 3D polychromatic code

    International Nuclear Information System (INIS)

    One possible design for a fourth-generation light source is the high-gain harmonic generation (HGHG) free-electron laser (FEL). Here, a coherent seed with a wavelength at a subharmonic of the desired output radiation interacts with the electron beam in an energy-modulating section. This energy modulation is then converted into spatial bunching while traversing a dispersive section (a three-dipole chicane). The final step is passage through a radiative section, an undulator tuned to the desired higher harmonic output wavelength. The coherent seed serves to remove noise and can be at a much lower subharmonic of the output radiation, thus eliminating the concerns found in self-amplified spontaneous emission (SASE) and seeded FELs, respectively. Recently, a 3D code that includes multiple frequencies, multiple undulatory (both in quantity and/or type), quadruple magnets, and dipole magnets was developed to easily simulate HGHG. Here, a brief review of the HGHG theory, the code development, the Accelerator Test Facility's (ATF) HGHG FEL experimental parameters, and the parameter analysis from simulations of this specific experiment will be discussed

  5. Parameter analysis for a high-gain harmonic generation FEL using a recently developed 3D polychromatic code

    International Nuclear Information System (INIS)

    One possible design for a fourth-generation light source is the high-gain harmonic generation (HGHG) free-electron laser (FEL). Here, a coherent seed with a wavelength at a subharmonic of the desired output radiation interacts with the electron beam in an energy-modulating section. This energy modulation is then converted into spatial bunching while traversing a dispersive section (a three-dipole chicane). The final step is passage through an undulator tuned to the desired higher harmonic output wavelength. The coherent seed serves to suppress and can be at a much lower subharmonic of the output radiation. Recently, a 3D code that includes multiple frequencies, multiple undulators (both in quantity and/or type), quadrupole magnets, and dipole magnets was developed to easily simulate HGHG. Here, a brief review of the HGHG theory, the code development, the Accelerator Test Facility's (ATF) HGHG FEL experimental parameters, and the parameter analysis from simulations of this specific experiment will be discussed

  6. Biomimetic component coating on 3D scaffolds using high bioactivity of mesoporous bioactive ceramics

    Directory of Open Access Journals (Sweden)

    Yun HS

    2011-10-01

    coated on MBG-PCL scaffolds after immersing in SBF containing dilute collagen-I solution only for 24 hours due to the high bone-forming bioactivity of MBG. Both cell affinity and osteoconductivity of MBG-PCL scaffolds were dramatically enhanced by this precoating process.Conclusion: The precoating process of ECM components on MBG-PCL scaffold using a high bioactivity of MBG was not only effective in enhancing the functionality of scaffolds but also effective in eliminating the unexpected side effect. The MBG-PCL scaffold-coated ECM components ideally satisfied the required conditions of scaffold in tissue engineering, including 3D well-interconnected pore structures with high porosity, good bioactivity, enhanced cell affinity, biocompatibility, osteoconductivity, and sufficient mechanical properties, and promise excellent potential application in the field of biomaterials.Keywords: biomimic, mesoporous, ECM components, scaffold, bone regeneration

  7. Feasibility study on 3-D shape analysis of high-aspect-ratio features using through-focus scanning optical microscopy

    Science.gov (United States)

    Attota, Ravi Kiran; Weck, Peter; Kramar, John A.; Bunday, Benjamin; Vartanian, Victor

    2016-01-01

    In-line metrologies currently used in the semiconductor industry are being challenged by the aggressive pace of device scaling and the adoption of novel device architectures. Metrology and process control of three-dimensional (3-D) high-aspect-ratio (HAR) features are becoming increasingly important and also challenging. In this paper we present a feasibility study of through-focus scanning optical microscopy (TSOM) for 3-D shape analysis of HAR features. TSOM makes use of 3-D optical data collected using a conventional optical microscope for 3-D shape analysis. Simulation results of trenches and holes down to the 11 nm node are presented. The ability of TSOM to analyze an array of HAR features or a single isolated HAR feature is also presented. This allows for the use of targets with area over 100 times smaller than that of conventional gratings, saving valuable real estate on the wafers. Indications are that the sensitivity of TSOM may match or exceed the International Technology Roadmap for Semiconductors (ITRS) measurement requirements for the next several years. Both simulations and preliminary experimental results are presented. The simplicity, lowcost, high throughput, and nanometer scale 3-D shape sensitivity of TSOM make it an attractive inspection and process monitoring solution for nanomanufacturing. PMID:27464112

  8. Feasibility study on 3-D shape analysis of high-aspect-ratio features using through-focus scanning optical microscopy.

    Science.gov (United States)

    Attota, Ravi Kiran; Weck, Peter; Kramar, John A; Bunday, Benjamin; Vartanian, Victor

    2016-07-25

    In-line metrologies currently used in the semiconductor industry are being challenged by the aggressive pace of device scaling and the adoption of novel device architectures. Metrology and process control of three-dimensional (3-D) high-aspect-ratio (HAR) features are becoming increasingly important and also challenging. In this paper we present a feasibility study of through-focus scanning optical microscopy (TSOM) for 3-D shape analysis of HAR features. TSOM makes use of 3-D optical data collected using a conventional optical microscope for 3-D shape analysis. Simulation results of trenches and holes down to the 11 nm node are presented. The ability of TSOM to analyze an array of HAR features or a single isolated HAR feature is also presented. This allows for the use of targets with area over 100 times smaller than that of conventional gratings, saving valuable real estate on the wafers. Indications are that the sensitivity of TSOM may match or exceed the International Technology Roadmap for Semiconductors (ITRS) measurement requirements for the next several years. Both simulations and preliminary experimental results are presented. The simplicity, lowcost, high throughput, and nanometer scale 3-D shape sensitivity of TSOM make it an attractive inspection and process monitoring solution for nanomanufacturing. PMID:27464112

  9. Hybrid wide-field and scanning microscopy for high-speed 3D imaging.

    Science.gov (United States)

    Duan, Yubo; Chen, Nanguang

    2015-11-15

    Wide-field optical microscopy is efficient and robust in biological imaging, but it lacks depth sectioning. In contrast, scanning microscopic techniques, such as confocal microscopy and multiphoton microscopy, have been successfully used for three-dimensional (3D) imaging with optical sectioning capability. However, these microscopic techniques are not very suitable for dynamic real-time imaging because they usually take a long time for temporal and spatial scanning. Here, a hybrid imaging technique combining wide-field microscopy and scanning microscopy is proposed to accelerate the image acquisition process while maintaining the 3D optical sectioning capability. The performance was demonstrated by proof-of-concept imaging experiments with fluorescent beads and zebrafish liver.

  10. Parameter Estimation of Fossil Oysters from High Resolution 3D Point Cloud and Image Data

    Science.gov (United States)

    Djuricic, Ana; Harzhauser, Mathias; Dorninger, Peter; Nothegger, Clemens; Mandic, Oleg; Székely, Balázs; Molnár, Gábor; Pfeifer, Norbert

    2014-05-01

    A unique fossil oyster reef was excavated at Stetten in Lower Austria, which is also the highlight of the geo-edutainment park 'Fossilienwelt Weinviertel'. It provides the rare opportunity to study the Early Miocene flora and fauna of the Central Paratethys Sea. The site presents the world's largest fossil oyster biostrome formed about 16.5 million years ago in a tropical estuary of the Korneuburg Basin. About 15,000 up to 80-cm-long shells of Crassostrea gryphoides cover a 400 m2 large area. Our project 'Smart-Geology for the World's largest fossil oyster reef' combines methods of photogrammetry, geology and paleontology to document, evaluate and quantify the shell bed. This interdisciplinary approach will be applied to test hypotheses on the genesis of the taphocenosis (e.g.: tsunami versus major storm) and to reconstruct pre- and post-event processes. Hence, we are focusing on using visualization technologies from photogrammetry in geology and paleontology in order to develop new methods for automatic and objective evaluation of 3D point clouds. These will be studied on the basis of a very dense surface reconstruction of the oyster reef. 'Smart Geology', as extension of the classic discipline, exploits massive data, automatic interpretation, and visualization. Photogrammetry provides the tools for surface acquisition and objective, automated interpretation. We also want to stress the economic aspect of using automatic shape detection in paleontology, which saves manpower and increases efficiency during the monitoring and evaluation process. Currently, there are many well known algorithms for 3D shape detection of certain objects. We are using dense 3D laser scanning data from an instrument utilizing the phase shift measuring principle, which provides accurate geometrical basis < 3 mm. However, the situation is difficult in this multiple object scenario where more than 15,000 complete or fragmentary parts of an object with random orientation are found. The goal

  11. High-detail 3D capture and non-sequential alignment of facial performance

    OpenAIRE

    Klaudiny M.; Hilton A.

    2012-01-01

    This paper presents a novel system for the 3D capture of facial performance using standard video and lighting equipment. The mesh of an actor's face is tracked non-sequentially throughout a performance using multi-view image sequences. The minimum spanning tree calculated in expression dissimilarity space defines the traversal of the sequences optimal with respect to error accumulation. A robust patch-based frame-to-frame surface alignment combined with the optimal traversal significantly red...

  12. Solid friction at high sliding velocities: an explicit 3D dynamical SPH approach

    OpenAIRE

    Maveyraud, C.; Benz, W.; Ouillon, G.; Sornette, A.; Sornette, D.

    1998-01-01

    We present realistic 3D numerical simulations of elastic bodies sliding on top of each other in a regime of velocities ranging from meters to tens of meters per second using the so-called Smoothed Particle Hydrodynamics (SPH) method. Our investigations are restricted to regimes of pressure and roughness where only elastic deformations occur between asperities at the contact surface between the slider block and the substrate. In this regime, solid friction is due to the generation of vibration...

  13. 3D silicon pixel detectors for the High-Luminosity LHC

    CERN Document Server

    Lange, J; Cavallaro, E; Förster, F; Grinstein, S; Paz, I López; Manna, M; Pellegrini, G; Quirion, D; Terzo, S; Furelos, D Vázquez

    2016-01-01

    3D silicon pixel detectors have been investigated as radiation-hard candidates for the innermost layers of the HL-LHC upgrade of the ATLAS pixel detector. 3D detectors are already in use today in the ATLAS IBL and AFP experiments. These are based on 50x250 um2 large pixels connected to the FE-I4 readout chip. Detectors of this generation were irradiated to HL-LHC fluences and demonstrated excellent radiation hardness with operational voltages as low as 180 V and power dissipation of 12--15 mW/cm2 at a fluence of about 1e16 neq/cm2, measured at -25 degree C. Moreover, to cope with the higher occupancies expected at the HL-LHC, a first run of a new generation of 3D detectors designed for the HL-LHC was produced at CNM with small pixel sizes of 50x50 and 25x100 um2, matched to the FE-I4 chip. They demonstrated a good performance in the laboratory and in beam tests with hit efficiencies of about 97% at already 1--2V before irradiation.

  14. High Precision 3D Facial Image Database%高精度三维人脸图像数据库

    Institute of Scientific and Technical Information of China (English)

    许磊; 黎智辉; 王俊娟; 谢兰迟; 张宁; 王永强; 郭晶晶

    2015-01-01

    Three-dimensional (3D) facial database can be wildly used in computer vision, animated drawing designing, medicine and etc. In forensic science, facial image database is used to classify face features, calculate the distribution of face features, and train the model. These analyses are the base for face identification and recognition. 3D facial image database can provide more information than traditional 2D database. For example, the special structure and shape in 3D facial image include multi-view profile. The 3D facial image capturing methods include multi-view geometry information, structured light and 3D scanning. These methods have different capturing devices and environments. There are several typical 3D facial image databases such as the MPI from MPI lab and the BJUT-3D from BJUT, which have some disadvantages in resolution and precision. In this paper, we first reviewed MPI and BJUT-3D databases and their capturing environments. Then we established our high precision 3D facial image database of Chinese people. 1100 3D facial images had been captured, including their color texture and depth (geometry shape or point cloud) information with Artec Spider, a portable 3D scanner. The number of sampling points of the geometry shape was more than 20 million. The number of triangle surfaces of 3D image was more than 40 million. The results showed that the images in our database exhibited higher precision than those in BJUT-3D database when considering face shape, resolution and texture. Meanwhile, these images presented more details in mouth, nose, eyes etc. than the images in the other databases. The established database would support our further work in 3D facial identification and algorithm evaluation.%3D 人脸图像数据库广泛应用于计算机视觉、动画绘图设计、医学等很多领域。在法庭科学领域,采集三维人脸图像并建立数据库,可进行人像特征分类、统计人像特征的分布以及训练人像模型,这些分

  15. 3D analytical model for the SOI LDMOS with alternating silicon and high-k dielectric pillars

    Science.gov (United States)

    Yao, Jia-fei; Guo, Yu-feng; Xia, Tian; Zhang, Jun; Lin, Hong

    2016-08-01

    In this paper, a 3D analytical model for the SOI LDMOS with alternating silicon and high-k dielectric pillars (HK LDMOS) is presented. By solving the 3D Poisson's equation, the surface potential and electric field distribution are derived. A criterion for obtaining the optimal breakdown voltage and drift region doping concentration is obtained. The analytical results are well matched with the numerical results, which confirms the model validity. Based on these models and the numerical simulation, the electric field modulation mechanism and the breakdown characteristics of HK LDMOS are investigated.

  16. High-throughput analysis of horse sperms' 3D swimming patterns using computational on-chip imaging.

    Science.gov (United States)

    Su, Ting-Wei; Choi, Inkyum; Feng, Jiawen; Huang, Kalvin; Ozcan, Aydogan

    2016-06-01

    Using a high-throughput optical tracking technique that is based on partially-coherent digital in-line holography, here we report a detailed analysis of the statistical behavior of horse sperms' three-dimensional (3D) swimming dynamics. This dual-color and dual-angle lensfree imaging platform enables us to track individual 3D trajectories of ∼1000 horse sperms at sub-micron level within a sample volume of ∼9μL at a frame rate of 143 frames per second (FPS) and collect thousands of sperm trajectories within a few hours for statistical analysis of their 3D dynamics. Using this high-throughput imaging platform, we recorded >17,000 horse sperm trajectories that can be grouped into six major categories: irregular, linear, planar, helical, ribbon, and hyperactivated, where the hyperactivated swimming patterns can be further divided into four sub-categories, namely hyper-progressive, hyper-planar, hyper-ribbon, and star-spin. The large spatio-temporal statistics that we collected with this 3D tracking platform revealed that irregular, planar, and ribbon trajectories are the dominant 3D swimming patterns observed in horse sperms, which altogether account for >97% of the trajectories that we imaged in plasma-free semen extender medium. Through our experiments we also found out that horse seminal plasma in general increases sperms' straightness in their 3D trajectories, enhancing the relative percentage of linear swimming patterns and suppressing planar swimming patterns, while barely affecting the overall percentage of ribbon patterns. PMID:26826909

  17. High power density microbial fuel cell with flexible 3D graphene-nickel foam as anode

    Science.gov (United States)

    Wang, Hanyu; Wang, Gongming; Ling, Yichuan; Qian, Fang; Song, Yang; Lu, Xihong; Chen, Shaowei; Tong, Yexiang; Li, Yat

    2013-10-01

    The structure and electrical conductivity of anode play a significant role in the power generation of microbial fuel cells (MFCs). In this study, we developed a three-dimensional (3D) reduced graphene oxide-nickel (denoted as rGO-Ni) foam as an anode for MFC through controlled deposition of rGO sheets onto the nickel foam substrate. The loading amount of rGO sheets and electrode surface area can be controlled by the number of rGO loading cycles. 3D rGO-Ni foam anode provides not only a large accessible surface area for microbial colonization and electron mediators, but also a uniform macro-porous scaffold for effective mass diffusion of the culture medium. Significantly, at a steady state of the power generation, the MFC device with flexible rGO-Ni electrodes produced an optimal volumetric power density of 661 W m-3 calculated based on the volume of anode material, or 27 W m-3 based on the volume of the anode chamber. These values are substantially higher than that of plain nickel foam, and other conventional carbon based electrodes (e.g., carbon cloth, carbon felt, and carbon paper) measured in the same conditions. To our knowledge, this is the highest volumetric power density reported for mL-scale MFC device with a pure strain of Shewanella oneidensis MR-1. We also demonstrated that the MFC device can be operated effectively in a batch-mode at least for a week. These new 3D rGO-Ni electrodes show great promise for improving the power generation of MFC devices.The structure and electrical conductivity of anode play a significant role in the power generation of microbial fuel cells (MFCs). In this study, we developed a three-dimensional (3D) reduced graphene oxide-nickel (denoted as rGO-Ni) foam as an anode for MFC through controlled deposition of rGO sheets onto the nickel foam substrate. The loading amount of rGO sheets and electrode surface area can be controlled by the number of rGO loading cycles. 3D rGO-Ni foam anode provides not only a large accessible

  18. A High-Resolution 3D Weather Radar, MSG, and Lightning Sensor Observation Composite

    Science.gov (United States)

    Diederich, Malte; Senf, Fabian; Wapler, Kathrin; Simmer, Clemens

    2013-04-01

    Within the research group 'Object-based Analysis and SEamless prediction' (OASE) of the Hans Ertel Centre for Weather Research programme (HerZ), a data composite containing weather radar, lightning sensor, and Meteosat Second Generation observations is being developed for the use in object-based weather analysis and nowcasting. At present, a 3D merging scheme combines measurements of the Bonn and Jülich dual polarimetric weather radar systems (data provided by the TR32 and TERENO projects) into a 3-dimensional polar-stereographic volume grid, with 500 meters horizontal, and 250 meters vertical resolution. The merging takes into account and compensates for various observational error sources, such as attenuation through hydrometeors, beam blockage through topography and buildings, minimum detectable signal as a function of noise threshold, non-hydrometeor echos like insects, and interference from other radar systems. In addition to this, the effect of convection during the radar 5-minute volume scan pattern is mitigated through calculation of advection vectors from subsequent scans and their use for advection correction when projecting the measurements into space for any desired timestamp. The Meteosat Second Generation rapid scan service provides a scan in 12 spectral visual and infrared wavelengths every 5 minutes over Germany and Europe. These scans, together with the derived microphysical cloud parameters, are projected into the same polar stereographic grid used for the radar data. Lightning counts from the LINET lightning sensor network are also provided for every 2D grid pixel. The combined 3D radar and 2D MSG/LINET data is stored in a fully documented netCDF file for every 5 minute interval, and is made ready for tracking and object based weather analysis. At the moment, the 3D data only covers the Bonn and Jülich area, but the algorithms are planed to be adapted to the newly conceived DWD polarimetric C-Band 5 minute interval volume scan strategy. An

  19. A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals

    CERN Document Server

    Loudos, G K; Giokaris, N D; Styliaris, E; Archimandritis, S C; Varvarigou, A D; Papanicolas, C N; Majewski, S; Weisenberger, D; Pani, R; Scopinaro, F; Uzunoglu, N K; Maintas, D; Stefanis, K

    2003-01-01

    The results of studies conducted with a small field of view tomographic gamma camera based on a Position Sensitive Photomultiplier Tube are reported. The system has been used for the evaluation of radiopharmaceuticals in small animals. Phantom studies have shown a spatial resolution of 2 mm in planar and 2-3 mm in tomographic imaging. Imaging studies in mice have been carried out both in 2D and 3D. Conventional radiopharmaceuticals have been used and the results have been compared with images from a clinically used system.

  20. Technology development of 3D detectors for high energy physics and medical imaging

    CERN Document Server

    Pellegrini, G

    2003-01-01

    This thesis is concerned with the fabrication, characterisation and simulation of 3D semiconductor detectors. Due to their geometry, these detectors have more efficient charge collection properties than current silicon and gallium arsenide planar detectors. The unit cell of these detectors is hexagonal with a central anode surrounded by six cathode contacts. This geometry gives a uniform electric field with the maximum drift and depletion distance set by electrode spacing, 85m in this project, rather than detector thickness, as in the case of planar detectors (typically 100-300m). This results in lower applied biases (35-40 V in the work of this project) compared to >200 V in typical planar detectors. The reduction in bias offers the possibility of improved detector operation in the presence of bulk radiation damage as lower voltage reduces leakage current which limits the signal to noise ratio and hence the overall detector efficiency. In this work, 3D detectors realised in Si, GaAs and SiC have ...

  1. High frequency nanotube oscillator

    Science.gov (United States)

    Peng, Haibing; Zettl, Alexander K.

    2012-02-21

    A tunable nanostructure such as a nanotube is used to make an electromechanical oscillator. The mechanically oscillating nanotube can be provided with inertial clamps in the form of metal beads. The metal beads serve to clamp the nanotube so that the fundamental resonance frequency is in the microwave range, i.e., greater than at least 1 GHz, and up to 4 GHz and beyond. An electric current can be run through the nanotube to cause the metal beads to move along the nanotube and changing the length of the intervening nanotube segments. The oscillator can operate at ambient temperature and in air without significant loss of resonance quality. The nanotube is can be fabricated in a semiconductor style process and the device can be provided with source, drain, and gate electrodes, which may be connected to appropriate circuitry for driving and measuring the oscillation. Novel driving and measuring circuits are also disclosed.

  2. Comprehensive evaluation of high-steep slope stability and optimal high-steep slope design by 3D physical modeling

    Institute of Scientific and Technical Information of China (English)

    Xing-ping Lai; Peng-fei Shan; Mei-feng Cai; Fen-hua Ren; Wen-hui Tan

    2015-01-01

    High-steep slope stability and its optimal excavation design in Shuichang open pit iron mine were analyzed based on a large 3D physical simulation technique. An optimal excavation scheme with a relatively steeper slope angle was successfully implemented at the northwest wall between Nos. 4 and 5 exploration lines of Shuichang Iron Mine, taking into account the 3D scale effect. The phys-ico-mechanical properties of rock materials were obtained by laboratory tests conducted on sample cores from exploration drilling directly from the iron mine. A porous rock-like composite material was formed for the model, and the mechanical parameters of the material were assessed experimentally;specifically, the effect of water on the sample was quantitatively determined. We adopted an experimental setup using stiff modular applied static loading to carry out a visual excavation of the slope at a random depth. The setup was equipped with acous-tic emission (AE) sensors, and the experiments were monitored by crack optical acquirement, ground penetrating radar, and close-field pho-togrammetry to investigate the mechanisms of rock-mass destabilization in the high-steep slope. For the complex study area, the model re-sults indicated a clear correlation between the model’s destabilization resulting from slope excavation and the collected monitoring informa-tion. During the model simulation, the overall angle of the slope increased by 1–6 degrees in different sections. Dramatically, the modeled excavation scheme saved over 80 million tons of rock from extraction, generating enormous economic and ecological benefits.

  3. 3D printing of high-resolution PLA-based structures by hybrid electrohydrodynamic and fused deposition modeling techniques

    International Nuclear Information System (INIS)

    Recently, the three-dimensional (3D) printing technique has received much attention for shape forming and manufacturing. The fused deposition modeling (FDM) printer is one of the various 3D printers available and has become widely used due to its simplicity, low-cost, and easy operation. However, the FDM technique has a limitation whereby its patterning resolution is too low at around 200 μm. In this paper, we first present a hybrid mechanism of electrohydrodynamic jet printing with the FDM technique, which we name E-FDM. We then develop a novel high-resolution 3D printer based on the E-FDM process. To determine the optimal condition for structuring, we also investigated the effect of several printing parameters, such as temperature, applied voltage, working height, printing speed, flow-rate, and acceleration on the patterning results. This method was capable of fabricating both high resolution 2D and 3D structures with the use of polylactic acid (PLA). PLA has been used to fabricate scaffold structures for tissue engineering, which has different hierarchical structure sizes. The fabrication speed was up to 40 mm/s and the pattern resolution could be improved to 10 μm. (paper)

  4. Spatial 3D infrastructure: display-independent software framework, high-speed rendering electronics, and several new displays

    Science.gov (United States)

    Chun, Won-Suk; Napoli, Joshua; Cossairt, Oliver S.; Dorval, Rick K.; Hall, Deirdre M.; Purtell, Thomas J., II; Schooler, James F.; Banker, Yigal; Favalora, Gregg E.

    2005-03-01

    We present a software and hardware foundation to enable the rapid adoption of 3-D displays. Different 3-D displays - such as multiplanar, multiview, and electroholographic displays - naturally require different rendering methods. The adoption of these displays in the marketplace will be accelerated by a common software framework. The authors designed the SpatialGL API, a new rendering framework that unifies these display methods under one interface. SpatialGL enables complementary visualization assets to coexist through a uniform infrastructure. Also, SpatialGL supports legacy interfaces such as the OpenGL API. The authors" first implementation of SpatialGL uses multiview and multislice rendering algorithms to exploit the performance of modern graphics processing units (GPUs) to enable real-time visualization of 3-D graphics from medical imaging, oil & gas exploration, and homeland security. At the time of writing, SpatialGL runs on COTS workstations (both Windows and Linux) and on Actuality"s high-performance embedded computational engine that couples an NVIDIA GeForce 6800 Ultra GPU, an AMD Athlon 64 processor, and a proprietary, high-speed, programmable volumetric frame buffer that interfaces to a 1024 x 768 x 3 digital projector. Progress is illustrated using an off-the-shelf multiview display, Actuality"s multiplanar Perspecta Spatial 3D System, and an experimental multiview display. The experimental display is a quasi-holographic view-sequential system that generates aerial imagery measuring 30 mm x 25 mm x 25 mm, providing 198 horizontal views.

  5. Real-time patch sweeping for high-quality depth estimation in 3D video conferencing applications

    Science.gov (United States)

    Waizenegger, Wolfgang; Feldmann, Ingo; Schreer, Oliver

    2011-03-01

    In future 3D videoconferencing systems, depth estimation is required to support autostereoscopic displays and even more important, to provide eye contact. Real-time 3D video processing is currently possible, but within some limits. Since traditional CPU centred sub-pixel disparity estimation is computationally expensive, the depth resolution of fast stereo approaches is directly linked to pixel quantization and the selected stereo baseline. In this work we present a novel, highly parallelizable algorithm that is capable of dealing with arbitrary depth resolutions while avoiding texture interpolation related runtime penalties by application of GPU centred design. The cornerstone of our patch sweeping approach is the fusion of space sweeping and patch based 3D estimation techniques. Especially for narrow baseline multi-camera configurations, as commonly used for 3D videoconferencing systems (e.g. [1]), it preserves the strengths of both techniques and avoid their shortcomings at the same time. Moreover, we provide a sophisticated parameterization and quantization scheme that establishes a very good scalability of our algorithm in terms of computation time and depth estimation quality. Furthermore, we present an optimized CUDA implementation for a multi GPU setup in a cluster environment. For each GPU, it performs three pair wise high quality depth estimations for a trifocal narrow baseline camera configuration on a 256x256 image block within real-time.

  6. Oxygen lines in solar granulation. I. Testing 3D models against new observations with high spatial and spectral resolution

    CERN Document Server

    Pereira, Tiago M D; Asplund, Martin

    2009-01-01

    Aims: we seek to provide additional tests of the line formation of theoretical 3D solar photosphere models. In particular, we set out to test the spatially-resolved line formation at several viewing angles, from the solar disk-centre to the limb and focusing on atomic oxygen lines. The purpose of these tests is to provide additional information on whether the 3D model is suitable to derive the solar oxygen abundance. We also aim to empirically constrain the NLTE recipes for neutral hydrogen collisions, using the spatially-resolved observations of the OI 777 nm lines. Methods: using the Swedish 1-m Solar Telescope we obtained high-spatial-resolution observations of five atomic oxygen lines (along with lines for other species) for five positions on the solar disk. These observations have a high spatial and spectral resolution, and a continuum intensity contrast up to 9% at 615 nm. The theoretical line profiles were computed using the 3D model, with a full 3D NLTE treatment for oxygen and LTE for the other lines...

  7. 3D printing of high-resolution PLA-based structures by hybrid electrohydrodynamic and fused deposition modeling techniques

    Science.gov (United States)

    Zhang, Bin; Seong, Baekhoon; Nguyen, VuDat; Byun, Doyoung

    2016-02-01

    Recently, the three-dimensional (3D) printing technique has received much attention for shape forming and manufacturing. The fused deposition modeling (FDM) printer is one of the various 3D printers available and has become widely used due to its simplicity, low-cost, and easy operation. However, the FDM technique has a limitation whereby its patterning resolution is too low at around 200 μm. In this paper, we first present a hybrid mechanism of electrohydrodynamic jet printing with the FDM technique, which we name E-FDM. We then develop a novel high-resolution 3D printer based on the E-FDM process. To determine the optimal condition for structuring, we also investigated the effect of several printing parameters, such as temperature, applied voltage, working height, printing speed, flow-rate, and acceleration on the patterning results. This method was capable of fabricating both high resolution 2D and 3D structures with the use of polylactic acid (PLA). PLA has been used to fabricate scaffold structures for tissue engineering, which has different hierarchical structure sizes. The fabrication speed was up to 40 mm/s and the pattern resolution could be improved to 10 μm.

  8. Extension of the reactor dynamics code MGT-3D for pebblebed and blocktype high-temperature-reactors

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Dunfu

    2015-07-01

    The High Temperature Gas cooled Reactor (HTGR) is an improved, gas cooled nuclear reactor. It was chosen as one of the candidates of generation IV nuclear plants [1]. The reactor can be shut down automatically because of the negative reactivity feedback due to the temperature's increasing in designed accidents. It is graphite moderated and Helium cooled. The residual heat can be transferred out of the reactor core by inactive ways as conduction, convection, and thermal radiation during the accident. In such a way, a fuel temperature does not go beyond a limit at which major fission product release begins. In this thesis, the coupled neutronics and fluid mechanics code MGT-3D used for the steady state and time-dependent simulation of HTGRs, is enhanced and validated [2]. The fluid mechanics part is validated by SANA experiments in steady state cases as well as transient cases. The fuel temperature calculation is optimized by solving the heat conduction equation of the coated particles. It is applied in the steady state and transient simulation of PBMR, and the results are compared to the simulation with the old overheating model. New approaches to calculate the temperature profile of the fuel element of block-type HTGRs, and the calculation of the homogeneous conductivity of composite materials are introduced. With these new developments, MGT-3D is able to simulate block-type HTGRs as well. This extended MGT-3D is used to simulate a cuboid ceramic block heating experiment in the NACOK-II facility. The extended MGT-3D is also applied to LOFC and DLOFC simulation of GT-MHR. It is a fluid mechanics calculation with a given heat source. This calculation result of MGT-3D is verified with the calculation results of other codes. The design of the Japanese HTTR is introduced. The deterministic simulation of the LOFC experiment of HTTR is conducted with the Monte-Carlo code Serpent and MGT-3D, which is the LOFC Project organized by OECD/NEA [3]. With Serpent the burnup

  9. UAV based 3D digital surface model to estimate paleolandscape in high mountainous environment

    Science.gov (United States)

    Mészáros, János; Árvai, Mátyás; Kohán, Balázs; Deák, Márton; Nagy, Balázs

    2016-04-01

    Our method to present current state of a peat bog was focused on the possible use of a UAV-system and later Structure-from-motion algorithms as processing technique. The peat bog site is located on the Vinderel Plateau, Farcǎu Massif, Maramures Mountains (Romania). The peat bog (1530 m a.s.l., N47°54'11", E24°26'37") lies below Rugasu ridge (c. 1820 m a.s.l.) and the locality serves as a conservation area for fallen down coniferous trees. Peat deposits were formed in a landslide concavity on the western slope of Farcǎu Massif. Nowadays the site is surrounded by a completely deforested landscape, and Farcǎu Massif lies above the depressed treeline. The peat bog has an extraordinary geomorphological situation, because a gully reached the bog and drained the water. In the recent past sedimentological and dendrochronological researches have been initiated. However, an accurate 3D digital surface model also needed for a complex paleoenvironmental research. Last autumn the bog and its surroundings were finally surveyed by a multirotor UAV developed in-house based on an open-source flight management unit and its firmware. During this survey a lightweight action camera (mainly to decrease payload weight) was used to take aerial photographs. While our quadcopter is capable to fly automatically on a predefined flight route, several over- and sidelapping flight lines were generated prior to the actual survey on the ground using a control software running on a notebook. Despite those precautions, limited number of batteries and severe weather affected our final flights, resulting a reduced surveyed area around peat bog. Later, during the processing we looked for a reliable tool which powerful enough to process more than 500 photos taken during flights. After testing several software Agisoft PhotoScan was used to create 3D point cloud and mesh about bog and its environment. Due to large number of photographs PhotoScan had to be configured for network processing to get

  10. Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection.

    Directory of Open Access Journals (Sweden)

    Kamfai Chan

    Full Text Available Most molecular diagnostic assays require upfront sample preparation steps to isolate the target's nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques. Because molecular diagnostic methods are generally rather difficult to perform manually without highly trained users, automated and integrated systems are highly desirable but too costly for use at point-of-care or low-resource settings. Here, we showcase the development of a low-cost and rapid nucleic acid isolation and amplification platform by modifying entry-level 3D printers that cost between $400 and $750. Our modifications consisted of replacing the extruder with a tip-comb attachment that houses magnets to conduct magnetic particle-based nucleic acid extraction. We then programmed the 3D printer to conduct motions that can perform high-quality extraction protocols. Up to 12 samples can be processed simultaneously in under 13 minutes and the efficiency of nucleic acid isolation matches well against gold-standard spin-column-based extraction technology. Additionally, we used the 3D printer's heated bed to supply heat to perform water bath-based polymerase chain reactions (PCRs. Using another attachment to hold PCR tubes, the 3D printer was programmed to automate the process of shuttling PCR tubes between water baths. By eliminating the temperature ramping needed in most commercial thermal cyclers, the run time of a 35-cycle PCR protocol was shortened by 33%. This article demonstrates that for applications in resource-limited settings, expensive nucleic acid extraction devices and thermal cyclers that are used in many central laboratories can be potentially replaced by a device modified from inexpensive entry-level 3D printers.

  11. Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection.

    Science.gov (United States)

    Chan, Kamfai; Coen, Mauricio; Hardick, Justin; Gaydos, Charlotte A; Wong, Kah-Yat; Smith, Clayton; Wilson, Scott A; Vayugundla, Siva Praneeth; Wong, Season

    2016-01-01

    Most molecular diagnostic assays require upfront sample preparation steps to isolate the target's nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques. Because molecular diagnostic methods are generally rather difficult to perform manually without highly trained users, automated and integrated systems are highly desirable but too costly for use at point-of-care or low-resource settings. Here, we showcase the development of a low-cost and rapid nucleic acid isolation and amplification platform by modifying entry-level 3D printers that cost between $400 and $750. Our modifications consisted of replacing the extruder with a tip-comb attachment that houses magnets to conduct magnetic particle-based nucleic acid extraction. We then programmed the 3D printer to conduct motions that can perform high-quality extraction protocols. Up to 12 samples can be processed simultaneously in under 13 minutes and the efficiency of nucleic acid isolation matches well against gold-standard spin-column-based extraction technology. Additionally, we used the 3D printer's heated bed to supply heat to perform water bath-based polymerase chain reactions (PCRs). Using another attachment to hold PCR tubes, the 3D printer was programmed to automate the process of shuttling PCR tubes between water baths. By eliminating the temperature ramping needed in most commercial thermal cyclers, the run time of a 35-cycle PCR protocol was shortened by 33%. This article demonstrates that for applications in resource-limited settings, expensive nucleic acid extraction devices and thermal cyclers that are used in many central laboratories can be potentially replaced by a device modified from inexpensive entry-level 3D printers. PMID:27362424

  12. Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection

    Science.gov (United States)

    Chan, Kamfai; Coen, Mauricio; Hardick, Justin; Gaydos, Charlotte A.; Wong, Kah-Yat; Smith, Clayton; Wilson, Scott A.; Vayugundla, Siva Praneeth; Wong, Season

    2016-01-01

    Most molecular diagnostic assays require upfront sample preparation steps to isolate the target’s nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques. Because molecular diagnostic methods are generally rather difficult to perform manually without highly trained users, automated and integrated systems are highly desirable but too costly for use at point-of-care or low-resource settings. Here, we showcase the development of a low-cost and rapid nucleic acid isolation and amplification platform by modifying entry-level 3D printers that cost between $400 and $750. Our modifications consisted of replacing the extruder with a tip-comb attachment that houses magnets to conduct magnetic particle-based nucleic acid extraction. We then programmed the 3D printer to conduct motions that can perform high-quality extraction protocols. Up to 12 samples can be processed simultaneously in under 13 minutes and the efficiency of nucleic acid isolation matches well against gold-standard spin-column-based extraction technology. Additionally, we used the 3D printer’s heated bed to supply heat to perform water bath-based polymerase chain reactions (PCRs). Using another attachment to hold PCR tubes, the 3D printer was programmed to automate the process of shuttling PCR tubes between water baths. By eliminating the temperature ramping needed in most commercial thermal cyclers, the run time of a 35-cycle PCR protocol was shortened by 33%. This article demonstrates that for applications in resource-limited settings, expensive nucleic acid extraction devices and thermal cyclers that are used in many central laboratories can be potentially replaced by a device modified from inexpensive entry-level 3D printers. PMID:27362424

  13. Two Eyes, 3D Early Results: Stereoscopic vs 2D Representations of Highly Spatial Scientific Imagery

    Science.gov (United States)

    Price, Aaron

    2013-06-01

    "Two Eyes, 3D" is a 3-year NSF funded research project to study the educational impacts of using stereoscopic representations in informal settings. The first study conducted as part of the project tested children 5-12 on their ability to perceive spatial elements of slides of scientific objects shown to them in either stereoscopic or 2D format. Children were also tested for prior spatial ability. Early results suggest that stereoscopy does not have a major impact on perceiving spatial elements of an image, but it does have a more significant impact on how the children apply that knowledge when presented with a common sense situation. The project is run by the AAVSO and this study was conducted at the Boston Museum of Science.

  14. 3-D readout-electronics packaging for high-bandwidth massively paralleled imager

    Science.gov (United States)

    Kwiatkowski, Kris; Lyke, James

    2007-12-18

    Dense, massively parallel signal processing electronics are co-packaged behind associated sensor pixels. Microchips containing a linear or bilinear arrangement of photo-sensors, together with associated complex electronics, are integrated into a simple 3-D structure (a "mirror cube"). An array of photo-sensitive cells are disposed on a stacked CMOS chip's surface at a 45.degree. angle from light reflecting mirror surfaces formed on a neighboring CMOS chip surface. Image processing electronics are held within the stacked CMOS chip layers. Electrical connections couple each of said stacked CMOS chip layers and a distribution grid, the connections for distributing power and signals to components associated with each stacked CSMO chip layer.

  15. Biomimetic staggered composites with highly enhanced energy dissipation: Modeling, 3D printing, and testing

    Science.gov (United States)

    Zhang, Pu; Heyne, Mary A.; To, Albert C.

    2015-10-01

    We investigate the damping enhancement in a class of biomimetic staggered composites via a combination of design, modeling, and experiment. In total, three kinds of staggered composites are designed by mimicking the structure of bone and nacre. These composite designs are realized by 3D printing a rigid plastic and a viscous elastomer simultaneously. Greatly-enhanced energy dissipation in the designed composites is observed from both the experimental results and theoretical prediction. The designed polymer composites have loss modulus up to ~500 MPa, higher than most of the existing polymers. In addition, their specific loss modulus (up to 0.43 km2/s2) is among the highest of damping materials. The damping enhancement is attributed to the large shear deformation of the viscous soft matrix and the large strengthening effect from the rigid inclusion phase.

  16. Toward high-speed 3D nonlinear soft tissue deformation simulations using Abaqus software.

    Science.gov (United States)

    Idkaidek, Ashraf; Jasiuk, Iwona

    2015-12-01

    We aim to achieve a fast and accurate three-dimensional (3D) simulation of a porcine liver deformation under a surgical tool pressure using the commercial finite element software Abaqus. The liver geometry is obtained using magnetic resonance imaging, and a nonlinear constitutive law is employed to capture large deformations of the tissue. Effects of implicit versus explicit analysis schemes, element type, and mesh density on computation time are studied. We find that Abaqus explicit and implicit solvers are capable of simulating nonlinear soft tissue deformations accurately using first-order tetrahedral elements in a relatively short time by optimizing the element size. This study provides new insights and guidance on accurate and relatively fast nonlinear soft tissue simulations. Such simulations can provide force feedback during robotic surgery and allow visualization of tissue deformations for surgery planning and training of surgical residents. PMID:26530842

  17. Oscillations of the Boundary Layer and High-frequency QPOs

    Directory of Open Access Journals (Sweden)

    Blinova A. A.

    2014-01-01

    Full Text Available We observed persistent high-frequency oscillations of the boundary layer near an accreting, weakly-magnetized star in global 3D MHD simulations. The tilted dipole magnetic field is not strong enough to open a gap between the star and the disk. Instead, it forms a highly-wrapped azimuthal field near the surface of the star which slows down rotation of the disk matter, while a small tilt of the field excites oscillations of the boundary layer with a frequency below the Keplerian frequency. This mechanism may be responsible for the high-frequency oscillations in accreting neutron stars, white dwarfs and classical T Tauri stars.

  18. High linearity SPAD and TDC array for TCSPC and 3D ranging applications

    Science.gov (United States)

    Villa, Federica; Lussana, Rudi; Bronzi, Danilo; Dalla Mora, Alberto; Contini, Davide; Tisa, Simone; Tosi, Alberto; Zappa, Franco

    2015-01-01

    An array of 32x32 Single-Photon Avalanche-Diodes (SPADs) and Time-to-Digital Converters (TDCs) has been fabricated in a 0.35 μm automotive-certified CMOS technology. The overall dimension of the chip is 9x9 mm2. Each pixel is able to detect photons in the 300 nm - 900 nm wavelength range with a fill-factor of 3.14% and either to count them or to time stamp their arrival time. In photon-counting mode an in-pixel 6-bit counter provides photon-numberresolved intensity movies at 100 kfps, whereas in photon-timing mode the 10-bit in-pixel TDC provides time-resolved maps (Time-Correlated Single-Photon Counting measurements) or 3D depth-resolved (through direct time-of-flight technique) images and movies, with 312 ps resolution. The photodetector is a 30 μm diameter SPAD with low Dark Count Rate (120 cps at room temperature, 3% hot-pixels) and 55% peak Photon Detection Efficiency (PDE) at 450 nm. The TDC has a 6-bit counter and a 4-bit fine interpolator, based on a Delay Locked Loop (DLL) line, which makes the TDC insensitive to process, voltage, and temperature drifts. The implemented sliding-scale technique improves linearity, giving 2% LSB DNL and 10% LSB INL. The single-shot precision is 260 ps rms, comprising SPAD, TDC and driving board jitter. Both optical and electrical crosstalk among SPADs and TDCs are negligible. 2D fast movies and 3D reconstructions with centimeter resolution are reported.

  19. 3-D structure below Aevroe Island from high-resolution reflection seismic studies, southeastern Sweden

    International Nuclear Information System (INIS)

    Reflection seismology has served as a useful tool for imaging and mapping of fracture zones in crystalline rock along 2-D lines in nuclear waste disposal studies. Two 1-km-long perpendicular seismic reflection lines were acquired on Aevroe Island, southeast Sweden, in October 1996 in order to (1) test the seismic reflection method for future site investigations, (2) map known fracture zones, and (3) add to the Swedish database of reflection seismic studies of the shallow crystalline crust. An east-west line was shot with 5-m geophone and shot-point spacing, and a north-south line was shot with 10-m geophone and shotpoint spacing. An explosive source with a charge size of 100 g was used along both lines. The data clearly image three major dipping reflectors and one subhorizontal one in the upper 200 ms (600 m). The dipping reflectors (to the south, east, and northwest) intersect or project to the surface at or close to where surface-mapped fracture zones exist. The south-dipping reflector correlates with the top of a heavily fractured interval observed in a borehole (KAV01) at about 400 m. The subhorizontal zone at about 100--200 m correlates with a known fracture zone in the same borehole (KAV01). 3-D effects are apparent in the data, and only where the profiles cross can the true orientation of the reflecting events be determined. To properly orient and locate all events observed on the lines requires acquisition of 3-D data

  20. Mode transformation and frequency change with height in 3D numerical simulations of magneto-acoustic wave propagation in sunspots

    CERN Document Server

    Felipe, T; Collados, M

    2010-01-01

    Three-dimensional numerical simulations of magnetoacoustic wave propagation are performed in a sunspot atmosphere with a computational domain covering from the photosphere to the chromosphere. The wave source, with properties resembling the solar spectrum, is located at different distances from the axis of the sunspot for each simulation. These results are compared with the theory of mode transformation and also with observational features. Simulations show that the dominant oscillation frequency in the chromosphere decreases with the radial distance from the sunspot axis. The energy flux of the different wave modes involved, including de Alfv\\'en mode, is evaluated and discussed.

  1. A HIGHLY COLLIMATED WATER MASER BIPOLAR OUTFLOW IN THE CEPHEUS A HW3d MASSIVE YOUNG STELLAR OBJECT

    Energy Technology Data Exchange (ETDEWEB)

    Chibueze, James O.; Imai, Hiroshi; Tafoya, Daniel; Omodaka, Toshihiro; Chong, Sze-Ning [Department of Physics and Astronomy, Graduate School of Science and Engineering, Kagoshima University, 1-21-35 Korimoto, Kagoshima 890-0065 (Japan); Kameya, Osamu; Hirota, Tomoya [Mizusawa VLBI Observatory, National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Torrelles, Jose M., E-mail: james@milkyway.sci.kagoshima-u.ac.jp [Instituto de Ciencias del Espacio (CSIC)-UB/IEEC, Facultat de Fisica, Universitat de Barcelona, Marti i Franques 1, E-08028 Barcelona (Spain)

    2012-04-01

    We present the results of multi-epoch very long baseline interferometry (VLBI) water (H{sub 2}O) maser observations carried out with the VLBI Exploration of Radio Astrometry toward the Cepheus A HW3d object. We measured for the first time relative proper motions of the H{sub 2}O maser features, whose spatio-kinematics traces a compact bipolar outflow. This outflow looks highly collimated and expanding through {approx}280 AU (400 mas) at a mean velocity of {approx}21 km s{sup -1} ({approx}6 mas yr{sup -1}) without taking into account the turbulent central maser cluster. The opening angle of the outflow is estimated to be {approx}30 Degree-Sign . The dynamical timescale of the outflow is estimated to be {approx}100 years. Our results provide strong support that HW3d harbors an internal massive young star, and the observed outflow could be tracing a very early phase of star formation. We also have analyzed Very Large Array archive data of 1.3 cm continuum emission obtained in 1995 and 2006 toward Cepheus A. The comparative result of the HW3d continuum emission suggests the possibility of the existence of distinct young stellar objects in HW3d and/or strong variability in one of their radio continuum emission components.

  2. Automatic Building Damage Detection Method Using High-Resolution Remote Sensing Images and 3d GIS Model

    Science.gov (United States)

    Tu, Jihui; Sui, Haigang; Feng, Wenqing; Song, Zhina

    2016-06-01

    In this paper, a novel approach of building damaged detection is proposed using high resolution remote sensing images and 3D GIS-Model data. Traditional building damage detection method considers to detect damaged building due to earthquake, but little attention has been paid to analyze various building damaged types(e.g., trivial damaged, severely damaged and totally collapsed.) Therefore, we want to detect the different building damaged type using 2D and 3D feature of scenes because the real world we live in is a 3D space. The proposed method generalizes that the image geometric correction method firstly corrects the post-disasters remote sensing image using the 3D GIS model or RPC parameters, then detects the different building damaged types using the change of the height and area between the pre- and post-disasters and the texture feature of post-disasters. The results, evaluated on a selected study site of the Beichuan earthquake ruins, Sichuan, show that this method is feasible and effective in building damage detection. It has also shown that the proposed method is easily applicable and well suited for rapid damage assessment after natural disasters.

  3. 3D branched ZnO nanowire arrays decorated with plasmonic au nanoparticles for high-performance photoelectrochemical water splitting.

    Science.gov (United States)

    Zhang, Xing; Liu, Yang; Kang, Zhenhui

    2014-03-26

    Plasmonic photoelectrochemical (PEC) water splitting is very promising in the conversion of abundant solar energy into chemical energy. However, the solar-to-hydrogen efficiencies reported so far are still too low for practical use, which can be improved by optimizing the design and synthesis of individual blocks (i. e., the compositions, sizes, shapes of the metal and the coupling semiconductors) and the assembly of these blocks into targeted three-dimensional (3D) structures. Here, we constructed a composite plasmonic metal/semiconductor photoanode by decorating gold nanoparticles (Au NPs) on 3D branched ZnO nanowire arrays (B-ZnO NWs) through a series of simple solution chemical routes. The 3D ordered Au/B-ZnO NWs photoanodes exhibited excellent PEC activities in both ultraviolet and visible region. The improved photoactivities in visible region were demonstrated to be caused by the surface-plasmon-resonance effect of Au NPs. The photoconversion efficiency of Au/B-ZnO NWs photoanode reached 0.52% under simulated sunlight illumination. This is a high value of solar-to-hydrogen efficiencies reported till nowadays for plasmonic PEC water splitting, which was mainly benefit from the extensive metal/semiconductor interfaces for efficient extraction of hot electron from Au NPs and excellent charge-carries collection efficiency of the 3D ordered Au/B-ZnO NWs photoelectrode. PMID:24598779

  4. An algorithm for the calculation of 3-D ICRF [Ion Cyclotron Range of Frequencies] fields in tokamak geometry

    International Nuclear Information System (INIS)

    A computational scheme is developed which permits tractable calculation of three-dimensional full-wave solutions to the Maxwell-Vlasov equations under typical Ion Cyclotron Range of Frequencies (ICRF) experimental conditions. The method is unique in that power deposition to the plasma is determined via the anti-Hermitian part of a truncated warm-plasma dielectric operator, rather than as the result of an assumed phenomenological collision frequency. The resulting computer code allows arbitrary variation of density, temperature, magnetic field, and minority concentration in the poloidal plane by performing a convolution of poloidal modes to produce a coupled system of differential equations in the radial variable. By assuming no inhomogeneity along the toroidal axis, an inverse transform over k/sub parallel/ is performed to yield the full three-dimensional field solutions. The application of the code to TFTR-like plasmas shows a mild resonance structure in antenna loading related to the changing number of wavelengths between antenna and the resonance layer. 48 figs

  5. Observation of a topological 3D Dirac semimetal phase in high-mobility Cd3As2

    Science.gov (United States)

    Neupane, M.; Xu, S.-Y.; Sankar, R.; Alidoust, N.; Bian, G.; Liu, Chang; Belopolski, I.; Chang, T.-R.; Jeng, H.-T.; Lin, H.; Bansil, A.; Chou, Fangcheng; Hasan, M. Z.

    2014-03-01

    Experimental identification of three-dimensional (3D) Dirac semimetals in solid state systems is critical for realizing exotic topological phenomena and quantum transport. Using high-resolution angle-resolved photoemission spectroscopy, we performed systematic electronic structure studies on well-known compound Cd3As2. For the first time, we observe a highly linear bulk Dirac cone located at the Brillouin zone center projected onto the (001) surface, which is consistent with a 3D Dirac semimetal phase in Cd3As2. Remarkably, an unusually high Dirac Fermion velocity is seen in samples where the mobility far exceeds 20,000 cm2/V.s suggesting that Cd3As2 can be a promising candidate as a hypercone analog of graphene in many device-applications, which can also incorporate topological quantum phenomena in a large gap setting. This work is primarily supported by U.S. DOE and Princeton University.

  6. High-speed dynamic 3D photoacoustic imaging of sentinel lymph node in a murine model using an ultrasound array.

    Science.gov (United States)

    Song, Liang; Kim, Chulhong; Maslov, Konstantin; Shung, K Kirk; Wang, Lihong V

    2009-08-01

    Noninvasive photoacoustic sentinel lymph node (SLN) mapping with high spatial resolution has the potential to improve the false negative rate and eliminate the use of radioactive tracers in SLN identification. In addition, the demonstrated high spatial resolution may enable physicians to replace SLN biopsy with fine needle aspiration biopsy, and thus reduce the risk of associated morbidity. The primary goal of this study is to demonstrate the feasibility of high-speed 3D photoacoustic imaging of the uptake and clearance dynamics of Evans blue dye in SLNs. The photoacoustic imaging system was developed with a 30 MHz ultrasound array and a kHz repetition rate laser system. It acquires one 3D photoacoustic image of 166 B-scan frames in 1 s, with axial, lateral, and elevational resolutions of 25, 70, and 200 microm, respectively. With optic-fiber based light delivery, the entire system is compact and is convenient to use. Upon injection of Evans blue, a blue dye currently used in clinical SLN biopsy, SLNs in mice and rats were accurately and noninvasively mapped in vivo using our imaging system. In our experiments, the SLNs were found to be located at approximately 0.65 mm below the skin surface in mice and approximately 1.2 mm in rats. In some cases, lymph vessels and lymphatic valves were also imaged. The dye dynamics--accumulation and clearance--in SLNs were quantitatively monitored by sequential 3D imaging with temporal resolution of as high as approximately 6 s. The demonstrated capability suggests that high-speed 3D photoacoustic imaging should facilitate the understanding of the dynamics of various dyes in SLNs and potentially help identify SLNs with high accuracy. PMID:19746805

  7. 3D hybrid-porous carbon derived from carbonization of metal organic frameworks for high performance supercapacitors

    Science.gov (United States)

    Bao, Weizhai; Mondal, Anjon Kumar; Xu, Jing; Wang, Chengyin; Su, Dawei; Wang, Guoxiu

    2016-09-01

    We report a rational design and synthesis of 3D hybrid-porous carbon with a hierarchical pore architecture for high performance supercapacitors. It contains micropores (<2 nm diameter) and mesopores (2-4 nm), derived from carbonization of unique porous metal organic frameworks (MOFs). Owning to the synergistic effect of micropores and mesopores, the hybrid-porous carbon has exceptionally high ion-accessible surface area and low ion diffusion resistance, which is desired for supercapacitor applications. When applied as electrode materials in supercapacitors, 3D hybrid-porous carbon demonstrates a specific capacitance of 332 F g-1 at a constant charge/discharge current of 500 mA g-1. The supercapacitors can endure more than 10,000 cycles without degradation of capacitance.

  8. First MMS Observations of High Time Resolution 3D Electric and Magnetic fields at the Dayside Magnetopause.

    Science.gov (United States)

    Torbert, R. B.; Burch, J. L.; Russell, C. T.; Magnes, W.; Ergun, R. E.; Lindqvist, P. A.; Le Contel, O.; Vaith, H.; Macri, J.; Myers, S.; Rau, D.; Needell, J.; King, B.; Granoff, M.; Chutter, M.; Dors, I.; Argall, M. R.; Shuster, J. R.; Olsson, G.; Marklund, G. T.; Khotyaintsev, Y. V.; Eriksson, A. I.; Kletzing, C.; Bounds, S. R.; Anderson, B. J.; Baumjohann, W.; Steller, M.; Bromund, K. R.; Le, G.; Nakamura, R.; Strangeway, R. J.; Leinweber, H. K.; Tucker, S.; Westfall, J.; Fischer, D.; Plaschke, F.; Pollock, C. J.; Giles, B. L.; Moore, T. E.; Mauk, B.; Fuselier, S. A.

    2015-12-01

    The electrodynamics at the magnetopause is key to our understanding of ion and electron acceleration within reconnection regions. The Magnetospheric Multiscale (MMS) fleet of four spacecraft was launched into its Phase-1 equatorial orbit of 12 Re apogee specifically to investigate these regions at the Earth's magnetopause. In addition to a comprehensive suite of particle measurements, MMS makes very high time resolution 3D electric and magnetic field measurements of high accuracy using flux-gate, search coil, 3-axis double probe, and electron drift sensors. In September 2015, the MMS fleet will begin to encounter the dusk-side magnetopause in its initial configuration of approximately 160 km separation, allowing investigation of the spatial and temporal characteristics of important electrodynamics during reconnection. Using these field and particle measurements, we present first observations of 3D magnetic and electric fields (including their parallel component), and inferred current sheets, during active magnetopause crossings using the highest time resolution data available on MMS.

  9. High resolution 3D imaging of bump-bonds by means of synchrotron radiation computed laminography

    Science.gov (United States)

    Cecilia, A.; Hamann, E.; Koenig, T.; Xu, F.; Cheng, Y.; Helfen, L.; Ruat, M.; Scheel, M.; Zuber, M.; Baumbach, T.; Fauler, A.; Fiederle, M.

    2013-12-01

    During the flip-chip bonding process of a semiconductor sensor onto readout electronics, a formation of defects may take place, like solder joint displacements, voids, cracks, pores and bridges. This may result in blind spots on the detector, which are insensitive to photons and thus reduce the detector performance. In this work, the flip-chip interconnections of selected CdTe and GaAs Medipix detectors were investigated by synchrotron radiation computed laminography at a micrometer scale. The analysis of the volume rendering proved the presence of voids in the CdTe sensor flip-chip interconnections, with sizes between 3 μm and 9 μm. These voids can be harmful for the long term use of the device, because their presence weakens the adhesive strength between a contact and the readout electronics. Consequently, their formation needs to be avoided. The GaAs Medipix detectors investigated include two sensors that were produced with different flip-chip methods. The comparison of the 3D renderings of the bump-bond interconnections in the two GaAs sensors demonstrated the presence of a misalignment in the range of 5-12 μm between pixel passivation and bump-bonds in the detector produced with an older technique. In contrast to this, no misalignment was observed for the most recently produced detector. The only remarkable observation is the presence of ``satellites'' of solder that do not compromise the detector operation.

  10. Automated Analysis of Barley Organs Using 3D Laser Scanning: An Approach for High Throughput Phenotyping

    Directory of Open Access Journals (Sweden)

    Stefan Paulus

    2014-07-01

    Full Text Available Due to the rise of laser scanning the 3D geometry of plant architecture is easy to acquire. Nevertheless, an automated interpretation and, finally, the segmentation into functional groups are still difficult to achieve. Two barley plants were scanned in a time course, and the organs were separated by applying a histogram-based classification algorithm. The leaf organs were represented by meshing algorithms, while the stem organs were parameterized by a least-squares cylinder approximation. We introduced surface feature histograms with an accuracy of 96% for the separation of the barley organs, leaf and stem. This enables growth monitoring in a time course for barley plants. Its reliability was demonstrated by a comparison with manually fitted parameters with a correlation R2 = 0:99 for the leaf area and R2 = 0:98 for the cumulated stem height. A proof of concept has been given for its applicability for the detection of water stress in barley, where the extension growth of an irrigated and a non-irrigated plant has been monitored.

  11. Possible use of small UAV to create high resolution 3D model of vertical rock faces

    Science.gov (United States)

    Mészáros, János; Kerkovits, Krisztian

    2014-05-01

    One of the newest and mostly emerging acquisition technologies is the use of small unmanned aerial vehicles (UAVs) to photogrammetry and remote sensing. Several successful research project or industrial use can be found worldwide (mine investigation, precision agriculture, mapping etc.) but those surveys are focusing mainly on the survey of horizontal areas. In our research a mixed acquisition method was developed and tested to create a dense, 3D model about a columnar outcrop close to Kő-hegy (Pest County). Our primary goal was to create a model whereat the pattern of different layers is clearly visible and measurable, as well as to test the robustness of our idea. Our method uses a consumer grade camera to take digital photographs about the outcrop. A small, custom made tricopter was built to carry the camera above middle and top parts of the rock, the bottom part can be photographed only from several ground positions. During the field survey ground control points were installed and measured using a kinematic correction GPS. These latter data were used during the georeferencing of generated point cloud. Free online services built on Structure from Motion (SfM) algorithms and desktop software also were tested to generate the relative point cloud and for further processing and analysis.

  12. Automated analysis of barley organs using 3D laser scanning: an approach for high throughput phenotyping.

    Science.gov (United States)

    Paulus, Stefan; Dupuis, Jan; Riedel, Sebastian; Kuhlmann, Heiner

    2014-01-01

    Due to the rise of laser scanning the 3D geometry of plant architecture is easy to acquire. Nevertheless, an automated interpretation and, finally, the segmentation into functional groups are still difficult to achieve. Two barley plants were scanned in a time course, and the organs were separated by applying a histogram-based classification algorithm. The leaf organs were represented by meshing algorithms, while the stem organs were parameterized by a least-squares cylinder approximation. We introduced surface feature histograms with an accuracy of 96% for the separation of the barley organs, leaf and stem. This enables growth monitoring in a time course for barley plants. Its reliability was demonstrated by a comparison with manually fitted parameters with a correlation R(2) = 0:99 for the leaf area and R(2) = 0:98 for the cumulated stem height. A proof of concept has been given for its applicability for the detection of water stress in barley, where the extension growth of an irrigated and a non-irrigated plant has been monitored. PMID:25029283

  13. Use of High resolution 3D Diffusion tensor imaging to study brain white matter development in live neonatal rats

    Directory of Open Access Journals (Sweden)

    Yu eCai

    2011-10-01

    Full Text Available High resolution diffusion tensor imaging (DTI can provide important information on brain development, yet it is challenging in live neonatal rats due to the small size of neonatal brain and motion-sensitive nature of DTI. Imaging in live neonatal rats has clear advantages over fixed brain scans, as longitudinal and functional studies would be feasible to understand neuro-developmental abnormalities. In this study, we developed imaging strategies that can be used to obtain high resolution 3D DTI images in live neonatal rats at postnatal day 5 (PND5 and postnatal day 14 (PND14, using only 3 hours of imaging acquisition time. An optimized 3D DTI pulse sequence and appropriate animal setup to minimize physiological motion artifacts are the keys to successful high resolution 3D DTI imaging. Thus, a 3D RARE DTI sequence with twin navigator echoes was implemented to accelerate imaging acquisition time and minimize motion artifacts. It has been suggested that neonatal mammals possess a unique ability to tolerate mild to moderate hypothermia and hypoxia without long term impact. Thus, we additionally utilized this ability to minimize motion artifacts in MR images by carefully suppressing the respiratory rate to around 15/min for PND5 and 30/min for PND14 using mild to moderate hypothermia. These imaging strategies have been successfully implemented to study how the effect of cocaine exposure in dams might affect brain development in their rat pups. Image quality resulting from this in vivo DTI study was comparable to ex vivo scans. FA values were also similar between the live and fixed brain scans. The capability of acquiring high quality in vivo DTI imaging offers a valuable opportunity to study many neurological disorders in brain development in an authentic living environment.

  14. High frequency ultrasound imaging of a single-species biofilm

    NARCIS (Netherlands)

    Shemesh, H.; Goertz, D. E.; van der Sluis, L. W. M.; de Jong, N.; Wu, M. K.; Wesselink, P. R.

    2007-01-01

    Objective: This study evaluated the feasibility of a high frequency ultrasound scan to examine the 3D morphology of Streptococcus mutans biofilms grown in vitro. Methods: Six 2-day S. mutans biofilms and six 7-day biofilms were grown on tissue culture membranes and on bovine dentine discs. A sterile

  15. High-quality 3-D coronary artery imaging on an interventional C-arm x-ray system

    Energy Technology Data Exchange (ETDEWEB)

    Hansis, Eberhard; Carroll, John D.; Schaefer, Dirk; Doessel, Olaf; Grass, Michael [Philips Technologie GmbH Forschungslaboratorien, Roentgenstrasse 24-26, 22335 Hamburg (Germany); Department of Medicine, Division of Cardiology, Health Sciences Center, University of Colorado, Denver, Colorado 80262 (United States); Philips Technologie GmbH Forschungslaboratorien, Roentgenstrasse 24-26, 22335 Hamburg (Germany); Institute of Biomedical Engineering, University of Karlsruhe, Kaiserstr. 12, 76131 Karlsruhe (Germany); Philips Technologie GmbH Forschungslaboratorien, Roentgenstrasse 24-26, 22335 Hamburg (Germany)

    2010-04-15

    Purpose: Three-dimensional (3-D) reconstruction of the coronary arteries during a cardiac catheter-based intervention can be performed from a C-arm based rotational x-ray angiography sequence. It can support the diagnosis of coronary artery disease, treatment planning, and intervention guidance. 3-D reconstruction also enables quantitative vessel analysis, including vessel dynamics from a time-series of reconstructions. Methods: The strong angular undersampling and motion effects present in gated cardiac reconstruction necessitate the development of special reconstruction methods. This contribution presents a fully automatic method for creating high-quality coronary artery reconstructions. It employs a sparseness-prior based iterative reconstruction technique in combination with projection-based motion compensation. Results: The method is tested on a dynamic software phantom, assessing reconstruction accuracy with respect to vessel radii and attenuation coefficients. Reconstructions from clinical cases are presented, displaying high contrast, sharpness, and level of detail. Conclusions: The presented method enables high-quality 3-D coronary artery imaging on an interventional C-arm system.

  16. Early Earth tectonics: A high-resolution 3D numerical modelling approach

    Science.gov (United States)

    Fischer, R.; Gerya, T.

    2014-12-01

    Early Earth had a higher amount of remaining radiogenic elements as well as a higher amount of leftover primordial heat. Both contributed to the increased temperature in the Earth's interior and it is mainly this increased mantle potential temperature ΔTp that controls the dynamics of the crust and upper mantle and the style of Early Earth tectonics. For a minor increase in temperature ΔTp buckling, delamination and Rayleigh-Taylor style dripping of the plate is observed in addition. For higher temperatures ΔTp > 250 K no subduction can be observed anymore and tectonics is dominated by delamination and Rayleigh-Taylor instabilities. We conduct 3D petrological-thermomechanical numerical modelling experiments of the crust and upper mantle under Early Earth conditions and a plume tectonics model setup. For varying crustal structures and an increased mantle potential temperature ΔTp, a thermal anomaly in the bottom temperature boundary introduces a plume. The model is able to self-sufficiently form depleted mantle lithosphere after repeated melt removal. New crust can be produced in the form of volcanics or plutonics. To simulate differentiation the newly formed crust can have a range in composition from basaltic over dacitic to granitic depending on its source rock. Models show large amounts of subcrustal decompression melting and consequently large amounts of new formed crust which in turn influences the dynamics. Mantle and crust are convecting separately. Dome-shaped plutons of mafic or felsic composition can be observed in the crust. Between these domes elongated belts of upper crust, volcanics and sediments are formed. These structures look similar to, for example, the Kaapvaal craton in South Africa where the elongated shape of the Barberton Greenstone Belt is surrounded by multiple plutons.

  17. Patterns of failure following high-dose 3-D conformal radiotherapy for high-grade astrocytomas: a quantitative dosimetric study

    International Nuclear Information System (INIS)

    Purpose: To analyze the failure patterns for patients with high-grade astrocytomas treated with high-dose conformal radiotherapy (CRT) using a quantitative technique to calculate the dose received by the CT- or MR-defined recurrence volume and to assess whether the final target volume margin used in the present dose escalation study requires redefinition before further escalation. Methods and Materials: Between 4/89 and 10/95, 71 patients with high-grade supratentorial astrocytomas were entered in a phase I/II dose escalation study using 3-D treatment planning and conformal radiotherapy. All patients were treated to either 70 or 80 Gy in conventional daily fractions of 1.8-2.0 Gy. The clinical and planning target volumes (CTV, PTV) consisted of successively smaller volumes with the final PTV defined as the enhancing lesion plus 0.5 cm margin. As of 10/95, 47 patients have CT or MR evidence of disease recurrence/progression. Of the 47 patients, 36 scans obtained at the time of recurrence were entered into the 3-D radiation therapy treatment planning system. After definition of the recurrent tumor volumes, the recurrence scan dataset was registered with the pretreatment CT dataset so that the actual dose received by the recurrent tumor volumes during treatment could be accurately calculated and then analyzed dosimetrically using dose-volume histograms. Recurrences were divided into several categories: 1) 'central', in which 95% or more of the recurrent tumor volume (Vrecur) was within D95, the region treated to high dose (95% of the prescription dose); 2) ''in-field,'' in which 80% or more of Vrecur was within the D95 isodose surface; 3) ''marginal,'' when between 20 and 80% of Vrecur was inside the D95 surface; 4) 'outside', in which less than 20% of Vrecur was inside the D95 surface. Results: In 29 of 36 patients, a solitary lesion was seen on recurrence scans. Of the 29 solitary recurrences, 26 were central, 3 were marginal, and none were outside. Multiple

  18. Benchmarking of 3D space charge codes using direct phase space measurements from photoemission high voltage DC gun

    CERN Document Server

    Bazarov, Ivan V; Gulliford, Colwyn; Li, Yulin; Liu, Xianghong; Sinclair, Charles K; Soong, Ken; Hannon, Fay

    2008-01-01

    We present a comparison between space charge calculations and direct measurements of the transverse phase space for space charge dominated electron bunches after a high voltage photoemission DC gun followed by an emittance compensation solenoid magnet. The measurements were performed using a double-slit setup for a set of parameters such as charge per bunch and the solenoid current. The data is compared with detailed simulations using 3D space charge codes GPT and Parmela3D with initial particle distributions created from the measured transverse and temporal laser profiles. Beam brightness as a function of beam fraction is calculated for the measured phase space maps and found to approach the theoretical maximum set by the thermal energy and accelerating field at the photocathode.

  19. High Frequency Trade Direction Prediction

    OpenAIRE

    Stav, Augustine Dexter

    2015-01-01

    High Frequency Trade Direction PredictionbyAugustine StavAbstract High frequency trading involves large volumes and rapid price changes. The Volume Synchronized Probability of Informed Trading (VPIN) metric characterizes order flow toxicity. This toxicity is the unbalance of order flow between informed traders who possess knowledge of future price directions and market makers who do not have this information. VPIN requires trades to be classified as buys or sells and works with volume as a pr...

  20. Stochastic 3D modeling of Ostwald ripening at ultra-high volume fractions of the coarsening phase

    Science.gov (United States)

    Spettl, A.; Wimmer, R.; Werz, T.; Heinze, M.; Odenbach, S.; Krill, C. E., III; Schmidt, V.

    2015-09-01

    We present a (dynamic) stochastic simulation model for 3D grain morphologies undergoing a grain coarsening phenomenon known as Ostwald ripening. For low volume fractions of the coarsening phase, the classical LSW theory predicts a power-law evolution of the mean particle size and convergence toward self-similarity of the particle size distribution; experiments suggest that this behavior holds also for high volume fractions. In the present work, we have analyzed 3D images that were recorded in situ over time in semisolid Al-Cu alloys manifesting ultra-high volume fractions of the coarsening (solid) phase. Using this information we developed a stochastic simulation model for the 3D morphology of the coarsening grains at arbitrary time steps. Our stochastic model is based on random Laguerre tessellations and is by definition self-similar—i.e. it depends only on the mean particle diameter, which in turn can be estimated at each point in time. For a given mean diameter, the stochastic model requires only three additional scalar parameters, which influence the distribution of particle sizes and their shapes. An evaluation shows that even with this minimal information the stochastic model yields an excellent representation of the statistical properties of the experimental data.

  1. "High-precision, reconstructed 3D model" of skull scanned by conebeam CT: Reproducibility verified using CAD/CAM data.

    Science.gov (United States)

    Katsumura, Seiko; Sato, Keita; Ikawa, Tomoko; Yamamura, Keiko; Ando, Eriko; Shigeta, Yuko; Ogawa, Takumi

    2016-01-01

    Computed tomography (CT) scanning has recently been introduced into forensic medicine and dentistry. However, the presence of metal restorations in the dentition can adversely affect the quality of three-dimensional reconstruction from CT scans. In this study, we aimed to evaluate the reproducibility of a "high-precision, reconstructed 3D model" obtained from a conebeam CT scan of dentition, a method that might be particularly helpful in forensic medicine. We took conebeam CT and helical CT images of three dry skulls marked with 47 measuring points; reconstructed three-dimensional images; and measured the distances between the points in the 3D images with a computer-aided design/computer-aided manufacturing (CAD/CAM) marker. We found that in comparison with the helical CT, conebeam CT is capable of reproducing measurements closer to those obtained from the actual samples. In conclusion, our study indicated that the image-reproduction from a conebeam CT scan was more accurate than that from a helical CT scan. Furthermore, the "high-precision reconstructed 3D model" facilitates reliable visualization of full-sized oral and maxillofacial regions in both helical and conebeam CT scans. PMID:26832374

  2. High Resolution 3d Imaging during the Construction of National Radioactive Waste Repository from BÁTAAPÁTI, Hungary

    Science.gov (United States)

    Gaich, A.; Deák, F.; Pötsch, M.

    2012-12-01

    investigation of the photorealistic 3D models reproducibility in the both cases JMX and SMX. Regularly geotechnical rock mass classifications (Q, RMR and GSI) were used on the basis of the 3D models without field experience of the given tunnel faces. All documentations were analysed with statistical methods considering the circumstances of scanning and picturing. The orientation of main characteristic discontinuities were defined by each geologist, but also some differences occured. These discrepancies had not occurred in the results of geotechnical evaluation. Due to several cases the information provided by the 3D modelling systems could be very useful in different phases of excavation works. These information were applied in geoscience researches for example in surface roughness determination, fracture system modelling of the host rock and geological or technical objects findings behind the shotcrete layer. Beside the above mentioned advanteges we have to emphasize that JMX and SMX systems provide contact free acqusition and assessment of rock and terrain surfaces by metric high resolution 3D images in very short time period.

  3. Absolute frequency and isotope shift of the magnesium (3 s2) 1S0→(3 s 3 d ) 1D2 two-photon transition by direct frequency-comb spectroscopy

    Science.gov (United States)

    Peters, E.; Reinhardt, S.; Hänsch, Th. W.; Udem, Th.

    2015-12-01

    We use a picosecond frequency-doubled mode-locked titanium sapphire laser to generate a frequency comb at 431 nm in order to probe the (3 s2) 1S0 →(3 s 3 d ) 1D2 transition in atomic magnesium. Using a second, self-referenced femtosecond frequency comb, the absolute transition frequency and the 24Mg and 26Mg isotope shift is determined relative to a global-positioning-system-referenced hydrogen maser. Our result for the transition frequency of the main isotope 24Mg of 1 391 128 606.14 (12 ) MHz agrees with previous measurements and reduces its uncertainty by four orders of magnitude. For the isotope shift we find δ ν26 ,24=3915.13 (39 ) MHz. Accurate values for transition frequencies in Mg are relevant in astrophysics and to test atomic structure calculations.

  4. 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

    Energy Technology Data Exchange (ETDEWEB)

    Wenzel, Carsten; Riefke, Björn; Gründemann, Stephan; Krebs, Alice; Christian, Sven; Prinz, Florian; Osterland, Marc; Golfier, Sven; Räse, Sebastian [Bayer Pharma AG, Global Drug Discovery, Muellerstrasse 178, 13353 Berlin (Germany); Ansari, Nariman [Physical Biology Group, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt (Germany); Esner, Milan; Bickle, Marc [Max Planck Institute of Molecular Cell Biology and Genetics, High-Throughput Technology Development Studio (TDS), Dresden (Germany); Pampaloni, Francesco; Mattheyer, Christian; Stelzer, Ernst H. [Physical Biology Group, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt (Germany); Parczyk, Karsten; Prechtl, Stefan [Bayer Pharma AG, Global Drug Discovery, Muellerstrasse 178, 13353 Berlin (Germany); Steigemann, Patrick, E-mail: Patrick.Steigemann@bayer.com [Bayer Pharma AG, Global Drug Discovery, Muellerstrasse 178, 13353 Berlin (Germany)

    2014-04-15

    Cancer cells in poorly vascularized tumor regions need to adapt to an unfavorable metabolic microenvironment. As distance from supplying blood vessels increases, oxygen and nutrient concentrations decrease and cancer cells react by stopping cell cycle progression and becoming dormant. As cytostatic drugs mainly target proliferating cells, cancer cell dormancy is considered as a major resistance mechanism to this class of anti-cancer drugs. Therefore, substances that target cancer cells in poorly vascularized tumor regions have the potential to enhance cytostatic-based chemotherapy of solid tumors. With three-dimensional growth conditions, multicellular tumor spheroids (MCTS) reproduce several parameters of the tumor microenvironment, including oxygen and nutrient gradients as well as the development of dormant tumor regions. We here report the setup of a 3D cell culture compatible high-content screening system and the identification of nine substances from two commercially available drug libraries that specifically target cells in inner MCTS core regions, while cells in outer MCTS regions or in 2D cell culture remain unaffected. We elucidated the mode of action of the identified compounds as inhibitors of the respiratory chain and show that induction of cell death in inner MCTS core regions critically depends on extracellular glucose concentrations. Finally, combinational treatment with cytostatics showed increased induction of cell death in MCTS. The data presented here shows for the first time a high-content based screening setup on 3D tumor spheroids for the identification of substances that specifically induce cell death in inner tumor spheroid core regions. This validates the approach to use 3D cell culture screening systems to identify substances that would not be detectable by 2D based screening in otherwise similar culture conditions. - Highlights: • Establishment of a novel method for 3D cell culture based high-content screening. • First reported high

  5. High rate performance of virus enabled 3D n-type Si anodes for lithium-ion batteries

    Energy Technology Data Exchange (ETDEWEB)

    Chen Xilin [Department of Chemical and Biomolecular Engineering, University of Maryland College Park, MD 20742 (United States); Gerasopoulos, Konstantinos [Department of Materials Science and Engineering, Institute for Systems Research, Department of Electrical and Computer Engineering, University of Maryland College Park, MD 20742 (United States); Guo Juchen [Department of Chemical and Biomolecular Engineering, University of Maryland College Park, MD 20742 (United States); Brown, Adam [Institute for Bioscience and Biotechology Research, Department of Plant Science and Landscape Architecture, University of Maryland College Park, MD 20742 (United States); Ghodssi, Reza [Department of Materials Science and Engineering, Institute for Systems Research, Department of Electrical and Computer Engineering, University of Maryland College Park, MD 20742 (United States); Culver, James N. [Institute for Bioscience and Biotechology Research, Department of Plant Science and Landscape Architecture, University of Maryland College Park, MD 20742 (United States); Wang Chunsheng, E-mail: cswang@umd.edu [Department of Chemical and Biomolecular Engineering, University of Maryland College Park, MD 20742 (United States)

    2011-05-30

    Research highlights: > A novel three-dimensional Tobacco mosaic virus (TMV) assembled n-type silicon anode is reported for the first time. > The combination of the large surface area conferred by the virus-enabled 3D Ni/TMV1cys current collector with the high electric conductivity of n-type Si rods results in excellent cyclic stability and rate capability for the core-shell n-type Si/Ni/TMV1cys anodes. > Electrochemical impedance spectroscopy reveals that the high electronic conductivity of n-type Si significantly reduces charge transfer resistance, thus even at high C-rates the capacity of the n-type Si is increased to almost 1000 mAh/g compared to undoped Si. - Abstract: A patterned 3D Si anode is fabricated by physical vapor deposition of n-type Si on a self-assembled TMV1cys-structured nickel current collector. The combination of the large surface area conferred by the virus-enabled 3D Ni/TMV1cys current collector with the high electric conductivity of n-type Si rods results in excellent cyclic stability and rate capability for the core-shell n-type Si/Ni/TMV1cys anodes. Electrochemical impedance spectroscopy reveals that the high electronic conductivity of n-type Si significantly reduces charge transfer resistance, thus even at high current densities the capacity of the n-type Si is increased to almost 630 mAh/g compared to undoped Si.

  6. A high throughput colorimetric assay of β-1,3-D-glucans by Congo red dye.

    Science.gov (United States)

    Semedo, Magda C; Karmali, Amin; Fonseca, Luís

    2015-02-01

    Mushroom strains contain complex nutritional biomolecules with a wide spectrum of therapeutic and prophylactic properties. Among these compounds, β-d-glucans play an important role in immuno-modulating and anti-tumor activities. The present work involves a novel colorimetric assay method for β-1,3-d-glucans with a triple helix tertiary structure by using Congo red. The specific interaction that occurs between Congo red and β-1,3-d-glucan was detected by bathochromic shift from 488 to 516 nm (>20 nm) in UV-Vis spectrophotometer. A micro- and high throughput method based on a 96-well microtiter plate was devised which presents several advantages over the published methods since it requires only 1.51 μg of polysaccharides in samples, greater sensitivity, speed, assay of many samples and very cheap. β-D-Glucans of several mushrooms (i.e., Coriolus versicolor, Ganoderma lucidum, Pleurotus ostreatus, Ganoderma carnosum, Hericium erinaceus, Lentinula edodes, Inonotus obliquus, Auricularia auricular, Polyporus umbellatus, Cordyseps sinensis, Agaricus blazei, Poria cocos) were isolated by using a sequence of several extractions with cold and boiling water, acidic and alkaline conditions and quantified by this microtiter plate method. FTIR spectroscopy was used to study the structural features of β-1,3-D-glucans in these mushroom samples as well as the specific interaction of these polysaccharides with Congo red. The effect of NaOH on triple helix conformation of β-1,3-D-glucans was investigated in several mushroom species. PMID:25555819

  7. Ordering Single Cells and Single Embryos in 3D Confinement: A New Device for High Content Screening.

    Science.gov (United States)

    Wollrab, Viktoria; Caballero, David; Thiagarajan, Raghavan; Riveline, Daniel

    2016-01-01

    Biological cells are usually observed on flat (2D) surfaces. This condition is not physiological, and phenotypes and shapes are highly variable. Screening based on cells in such environments have therefore serious limitations: cell organelles show extreme phenotypes, cell morphologies and sizes are heterogeneous and/or specific cell organelles cannot be properly visualized. In addition, cells in vivo are located in a 3D environment; in this situation, cells show different phenotypes mainly because of their interaction with the surrounding extracellular matrix of the tissue. In order to standardize and generate order of single cells in a physiologically-relevant 3D environment for cell-based assays, we report here the microfabrication and applications of a device for in vitro 3D cell culture. This device consists of a 2D array of microcavities (typically 10(5) cavities/cm(2)), each filled with single cells or embryos. Cell position, shape, polarity and internal cell organization become then normalized showing a 3D architecture. We used replica molding to pattern an array of microcavities, 'eggcups', onto a thin polydimethylsiloxane (PDMS) layer adhered on a coverslip. Cavities were covered with fibronectin to facilitate adhesion. Cells were inserted by centrifugation. Filling percentage was optimized for each system allowing up to 80%. Cells and embryos viability was confirmed. We applied this methodology for the visualization of cellular organelles, such as nucleus and Golgi apparatus, and to study active processes, such as the closure of the cytokinetic ring during cell mitosis. This device allowed the identification of new features, such as periodic accumulations and inhomogeneities of myosin and actin during the cytokinetic ring closure and compacted phenotypes for Golgi and nucleus alignment. We characterized the method for mammalian cells, fission yeast, budding yeast, C. elegans with specific adaptation in each case. Finally, the characteristics of this

  8. Development of 3D ultrasound needle guidance for high-dose-rate interstitial brachytherapy of gynaecological cancers

    Science.gov (United States)

    Rodgers, J.; Tessier, D.; D'Souza, D.; Leung, E.; Hajdok, G.; Fenster, A.

    2016-04-01

    High-dose-rate (HDR) interstitial brachytherapy is often included in standard-of-care for gynaecological cancers. Needles are currently inserted through a perineal template without any standard real-time imaging modality to assist needle guidance, causing physicians to rely on pre-operative imaging, clinical examination, and experience. While two-dimensional (2D) ultrasound (US) is sometimes used for real-time guidance, visualization of needle placement and depth is difficult and subject to variability and inaccuracy in 2D images. The close proximity to critical organs, in particular the rectum and bladder, can lead to serious complications. We have developed a three-dimensional (3D) transrectal US system and are investigating its use for intra-operative visualization of needle positions used in HDR gynaecological brachytherapy. As a proof-of-concept, four patients were imaged with post-insertion 3D US and x-ray CT. Using software developed in our laboratory, manual rigid registration of the two modalities was performed based on the perineal template's vaginal cylinder. The needle tip and a second point along the needle path were identified for each needle visible in US. The difference between modalities in the needle trajectory and needle tip position was calculated for each identified needle. For the 60 needles placed, the mean trajectory difference was 3.23 +/- 1.65° across the 53 visible needle paths and the mean difference in needle tip position was 3.89 +/- 1.92 mm across the 48 visible needles tips. Based on the preliminary results, 3D transrectal US shows potential for the development of a 3D US-based needle guidance system for interstitial gynaecological brachytherapy.

  9. 2-D/3-D quench simulation using ANSYS for epoxy impregnated $Nb_{3}$ Sn high field magnets

    CERN Document Server

    Yamada, R; Marscin, E; Rey, J M; Wake, M

    2003-01-01

    A quench program using ANSYS is developed for the high field collider magnet for 3-D analysis. Its computational procedure is explained. The quench program is applied to a one meter Nb/sub 3/Sn high field model magnet, which is epoxy impregnated. The quench simulation program is used to estimate the temperature and mechanical stress inside the coil as well as over the whole magnet. It is concluded that for the one meter magnet with the presented cross section and configuration, the thermal effects due to the quench is tolerable. But we need much more quench study and improvements in the design for longer magnets. (6 refs).

  10. Digitized crime scene forensics: automated trace separation of toolmarks on high-resolution 2D/3D CLSM surface data

    Science.gov (United States)

    Clausing, Eric; Vielhauer, Claus

    2015-03-01

    Locksmith forensics is an important and very challenging part of classic crime scene forensics. In prior work, we propose a partial transfer to the digital domain, to effectively support forensic experts and present approaches for a full process chain consisting of five steps: Trace positioning, 2D/3D acquisition with a confocal 3D laser scanning microscope, detection by segmentation, trace type determination, and determination of the opening method. In particular the step of trace segmentation on high-resolution 3D surfaces thereby turned out to be the part most difficult to implement. The reason for that is the highly structured and complex surfaces to be analyzed. These surfaces are cluttered with a high number of toolmarks, which overlap and distort each other. In Clausing et al., we present an improved approach for a reliable segmentation of relevant trace regions but without the possibility of separating single traces out of segmented trace regions. However, in our past research, especially features based on shape and dimension turned out to be highly relevant for a fully automated analysis and interpretation. In this paper, we consequently propose an approach for this separation. To achieve this goal, we use our segmentation approach and expand it with a combination of the watershed algorithm with a graph-based analysis. Found sub-regions are compared based on their surface character and are connected or divided depending on their similarity. We evaluate our approach with a test set of about 1,300 single traces on the exemplary locking cylinder component 'key pin' and thereby are able of showing the high suitability of our approach.

  11. Fabrication of continuous flow microfluidics device with 3D electrode structures for high throughput DEP applications using mechanical machining.

    Science.gov (United States)

    Zeinali, Soheila; Çetin, Barbaros; Oliaei, Samad Nadimi Bavil; Karpat, Yiğit

    2015-07-01

    Microfluidics is the combination of micro/nano fabrication techniques with fluid flow at microscale to pursue powerful techniques in controlling and manipulating chemical and biological processes. Sorting and separation of bio-particles are highly considered in diagnostics and biological analyses. Dielectrophoresis (DEP) has offered unique advantages for microfluidic devices. In DEP devices, asymmetric pair of planar electrodes could be employed to generate non-uniform electric fields. In DEP applications, facing 3D sidewall electrodes is considered to be one of the key solutions to increase device throughput due to the generated homogeneous electric fields along the height of microchannels. Despite the advantages, fabrication of 3D vertical electrodes requires a considerable challenge. In this study, two alternative fabrication techniques have been proposed for the fabrication of a microfluidic device with 3D sidewall electrodes. In the first method, both the mold and the electrodes are fabricated using high precision machining. In the second method, the mold with tilted sidewalls is fabricated using high precision machining and the electrodes are deposited on the sidewall using sputtering together with a shadow mask fabricated by electric discharge machining. Both fabrication processes are assessed as highly repeatable and robust. Moreover, the two methods are found to be complementary with respect to the channel height. Only the manipulation of particles with negative-DEP is demonstrated in the experiments, and the throughput values up to 105 particles / min is reached in a continuous flow. The experimental results are compared with the simulation results and the limitations on the fabrication techniques are also discussed.

  12. High-Frequency Rayleigh-Wave Method

    Institute of Scientific and Technical Information of China (English)

    Jianghai Xia; Richard D Millerg; Xu Yixian; Luo Yinhe; Chen Chao; Liu Jiangping; Julian Ivanov; Chong Zeng

    2009-01-01

    High-frequency (≥2 Hz) Rayleigh-wave data acquired with a multichannei recording sys-tem have been utilized to determine shear (S)-wave velocities in near-surface geophysics since the early 1980s. This overview article discusses the main research results of high-frequency surface-wave tech-niques achieved by research groups at the Kansas Geological Survey and China University of Geosciences in the last 15 years. The multichannel analysis of surface wave (MASW) method is a nou-iuvasive acoustic approach to estimate near-surface S-wave velocity. The differences between MASW results and direct borehole measurements are approximately 15% or less and random. Studies show that simultaneous inversion with higher modes and the fundamental mode can increase model resolution and an investigation depth. The other important seismic property, quality factor (Q), can also be estimated with the MASW method by inverting attenuation coefficients of Rayleigh waves. An inverted model (S-wave velocity or Q) obtained using a damped least-squares method can be assessed by an optimal damping vector in a vicinity of the inverted model determined by an objective function, which is the trace of a weighted sum of model-resolution and model-covariance matrices. Current developments include modeling high-frequency Rayleigh-waves in near-surface media, which builds a foundation for shallow seismic or Rayleigh-wave inversion in the time-offset domain; imaging dispersive energy with high resolution in the frequency-velocity domain and possibly with data in an arbitrary acquisition geometry, which opens a door for 3D surface-wave techniques; and successfully separating surface-wave modes, which provides a valuable tool to perform S-wave velocity profiling with high-horizontal resolution.

  13. High-speed 3D imaging using two-wavelength parallel-phase-shift interferometry.

    Science.gov (United States)

    Safrani, Avner; Abdulhalim, Ibrahim

    2015-10-15

    High-speed three dimensional imaging based on two-wavelength parallel-phase-shift interferometry is presented. The technique is demonstrated using a high-resolution polarization-based Linnik interferometer operating with three high-speed phase-masked CCD cameras and two quasi-monochromatic modulated light sources. The two light sources allow for phase unwrapping the single source wrapped phase so that relatively high step profiles having heights as large as 3.7 μm can be imaged in video rate with ±2  nm accuracy and repeatability. The technique is validated using a certified very large scale integration (VLSI) step standard followed by a demonstration from the semiconductor industry showing an integrated chip with 2.75 μm height copper micro pillars at different packing densities. PMID:26469586

  14. 3-D Modeling of Tomato Canopies Using a High-Resolution Portable Scanning Lidar for Extracting Structural Information

    OpenAIRE

    Fumiki Hosoi; Kazushige Nakabayashi; Kenji Omasa

    2011-01-01

    In the present study, an attempt was made to produce a precise 3D image of a tomato canopy using a portable high-resolution scanning lidar. The tomato canopy was scanned by the lidar from three positions surrounding it. Through the scanning, the point cloud data of the canopy were obtained and they were co-registered. Then, points corresponding to leaves were extracted and converted into polygon images. From the polygon images, leaf areas were accurately estimated with a mean absolute percent...

  15. 3s2S-3d2D electric quadrupole transitions for highly stripped Na-like ions

    International Nuclear Information System (INIS)

    A fully relativistic multiconfiguration Dirac-Fock method with Breit and QED corrections is used to calculated the 3s2S-3d2D (Z = 14-103) transition energy level separations, transition probabilities and oscillator strengths for the Na-like ions. In calculation, the author considered significant Breit and QED corrections, the results are in good agreement with recent experimental data and other theoretical values. The results show that the electric quadruple transition probabilities are in correspondence with those of E1 transitions and can not be ignored in high temperature laser plasma in ICF and MCF Fusion

  16. Denoising of high resolution small animal 3D PET data using the non-subsampled Haar wavelet transform

    Energy Technology Data Exchange (ETDEWEB)

    Ochoa Domínguez, Humberto de Jesús, E-mail: hochoa@uacj.mx [Departamento de Ingeniería Eléctrica y computación, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chih. (Mexico); Máynez, Leticia O. [Departamento de Ingeniería Eléctrica y computación, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chih. (Mexico); Vergara Villegas, Osslan O. [Departamento de Ingeniería Industrial, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chih. (Mexico); Mederos, Boris; Mejía, José M.; Cruz Sánchez, Vianey G. [Departamento de Ingeniería Eléctrica y computación, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chih. (Mexico)

    2015-06-01

    PET allows functional imaging of the living tissue. However, one of the most serious technical problems affecting the reconstructed data is the noise, particularly in images of small animals. In this paper, a method for high-resolution small animal 3D PET data is proposed with the aim to reduce the noise and preserve details. The method is based on the estimation of the non-subsampled Haar wavelet coefficients by using a linear estimator. The procedure is applied to the volumetric images, reconstructed without correction factors (plane reconstruction). Results show that the method preserves the structures and drastically reduces the noise that contaminates the image.

  17. 3D organization of high-speed compressible jets by tomographic PIV

    NARCIS (Netherlands)

    Violato, D.; Ceglia, G.; Tuinstra, M.; Scarano, F.

    2013-01-01

    This work investigates the three dimensional organization of compressible jets at high-speed regime by tomographic particle image velocimetry (TOMO PIV). Experiments are conducted at Mach numbers 0.3, 0.9 and 1.1 (underexpanded regime) across the end of the potential core within a large cylindrica

  18. Integrated Automotive High-Power LED-Lighting Systems in 3D-MID Technology

    NARCIS (Netherlands)

    Thomas, W.

    2014-01-01

    The growing energy consumption of lighting as well as rising luminous efficacies and -fluxes of high-power Light Emitting Diodes (LEDs) have contributed to the widespread use of LEDs in modern lighting systems. One of the most prominent users of the LED-technology is automotive (exterior) lighting.

  19. TOWARDS: 3D INTERNET

    OpenAIRE

    Ms. Swapnali R. Ghadge

    2013-01-01

    In today’s ever-shifting media landscape, it can be a complex task to find effective ways to reach your desired audience. As traditional media such as television continue to lose audience share, one venue in particular stands out for its ability to attract highly motivated audiences and for its tremendous growth potential the 3D Internet. The concept of '3D Internet' has recently come into the spotlight in the R&D arena, catching the attention of many people, and leading to a lot o...

  20. High-frequency complex pitch

    DEFF Research Database (Denmark)

    Santurette, Sébastien; Dau, Torsten

    2012-01-01

    Harmonics in a complex tone are typically considered unresolved when they interact with neighboring harmonics in the cochlea and cannot be heard out separately. Recent studies have suggested that the low pitch evoked by unresolved high-frequency harmonics may be coded via temporal fine-structure ......Harmonics in a complex tone are typically considered unresolved when they interact with neighboring harmonics in the cochlea and cannot be heard out separately. Recent studies have suggested that the low pitch evoked by unresolved high-frequency harmonics may be coded via temporal fine...

  1. An overset mesh approach for 3D mixed element high-order discretizations

    Science.gov (United States)

    Brazell, Michael J.; Sitaraman, Jayanarayanan; Mavriplis, Dimitri J.

    2016-10-01

    A parallel high-order Discontinuous Galerkin (DG) method is used to solve the compressible Navier-Stokes equations in an overset mesh framework. The DG solver has many capabilities including: hp-adaption, curved cells, support for hybrid, mixed-element meshes, and moving meshes. Combining these capabilities with overset grids allows the DG solver to be used in problems with bodies in relative motion and in a near-body off-body solver strategy. The overset implementation is constructed to preserve the design accuracy of the baseline DG discretization. Multiple simulations are carried out to validate the accuracy and performance of the overset DG solver. These simulations demonstrate the capability of the high-order DG solver to handle complex geometry and large scale parallel simulations in an overset framework.

  2. DEMONSTRATION OF 3D EFFECTS WITH HIGH GAIN AND EFFICIENCY IN A UV FEL OSCILLATOR

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Benson; George Biallas; Keith Blackburn; James Boyce; Donald Bullard; James Coleman; Cody Dickover; David Douglas; Forrest Ellingsworth; Pavel Evtushenko; Carlos Hernandez-Garcia; Christopher Gould; Joseph Gubeli; David Hardy; Kevin Jordan; John Klopf; James Kortze; Robert Legg; Matthew Marchlik; Steven Moore; George Neil; Thomas Powers; Daniel Sexton; Michelle D. Shinn; Christopher Tennant; Richard Walker; Anne Watson; Gwyn Williams; Frederick Wilson; Shukui Zhang

    2011-03-01

    We report on the performance of a high gain UV FEL oscillator operating on an energy recovery linac at Jefferson Lab. The high brightness of the electron beam leads to both gain and efficiency that cannot be reconciled with a one-dimensional model. Three-dimensional simulations do predict the performance with reasonable precision. Gain in excess of 100% per pass and an efficiency close to 1/2NW, where NW is the number of wiggler periods, is seen. The laser mirror tuning curves currently permit operation in the wavelength range of 438 to 362 nm. Another mirror set allows operation at longer wavelengths in the red with even higher gain and efficiency.

  3. Sub-nm 3D observation of human hair melanin by high-voltage STEM.

    Science.gov (United States)

    Imai, Takehito; Higuchi, Kimitaka; Yamamoto, Yuta; Arai, Shigeo; Nakano, Takashi; Tanaka, Nobuo

    2016-04-01

    The ultrastructure of melanin granules in human hair was studied using 1,000 kV high-voltage scanning transmission electron microscopy to successfully reconstruct three-dimensional images of the whole melanin granule. It was revealed that the melanin granule was composed of a membrane-like outer structure that included many spherical vesicles, and an inner matrix containing a sheet-like structure in the elongated direction of the melanin granule and a sheet-like arrays structure in the cross direction. The outer structure of the melanin granule was maintained even after exposure to hair-bleaching agents to decompose the melanin granule, suggesting that the outer structure was a highly robust structure and composition compared with the inner matrix . PMID:26705324

  4. A novel 3D detector configuration enabling high quantum efficiency, low crosstalk, and low output capacitance

    Science.gov (United States)

    Aurola, A.; Marochkin, V.; Tuuva, T.

    2016-03-01

    The benefits of pixelated planar direct conversion semiconductor radiation detectors comprising a thick fully depleted substrate are that they offer low crosstalk, small output capacitance, and that the planar configuration simplifies manufacturing. In order to provide high quantum efficiency for high energy X-rays and Gamma-rays such a radiation detector should be as thick as possible. The maximum thickness and thus the maximum quantum efficiency has been limited by the substrate doping concentration: the lower the substrate doping the thicker the detector can be before reaching the semiconductor material's electric breakdown field. Thick direct conversion semiconductor detectors comprising vertical three-dimensional electrodes protruding through the substrate have been previously proposed by Sherwood Parker in order to promote rapid detection of radiation. An additional advantage of these detectors is that their thickness is not limited by the substrate doping, i.e., the size of the maximum electric field value in the detector does not depend on detector thickness. However, the thicker the substrate of such three dimensional detectors is the larger the output capacitance is and thus the larger the output noise is. In the novel direct conversion pixelated radiation detector utilizing a novel three dimensional semiconductor architecture, which is proposed in this work, the detector thickness is not limited by the substrate doping and the output capacitance is small and does not depend on the detector thickness. In addition, by incorporating an additional node to the novel three-dimensional semiconductor architecture it can be utilized as a high voltage transistor that can deliver current across high voltages. Furthermore, it is possible to connect a voltage difference of any size to the proposed novel three dimensional semiconductor architecture provided that it is thick enough—this is a novel feature that has not been previously possible for semiconductor

  5. A novel 3D detector configuration enabling high quantum efficiency, low crosstalk, and low output capacitance

    International Nuclear Information System (INIS)

    The benefits of pixelated planar direct conversion semiconductor radiation detectors comprising a thick fully depleted substrate are that they offer low crosstalk, small output capacitance, and that the planar configuration simplifies manufacturing. In order to provide high quantum efficiency for high energy X-rays and Gamma-rays such a radiation detector should be as thick as possible. The maximum thickness and thus the maximum quantum efficiency has been limited by the substrate doping concentration: the lower the substrate doping the thicker the detector can be before reaching the semiconductor material's electric breakdown field. Thick direct conversion semiconductor detectors comprising vertical three-dimensional electrodes protruding through the substrate have been previously proposed by Sherwood Parker in order to promote rapid detection of radiation. An additional advantage of these detectors is that their thickness is not limited by the substrate doping, i.e., the size of the maximum electric field value in the detector does not depend on detector thickness. However, the thicker the substrate of such three dimensional detectors is the larger the output capacitance is and thus the larger the output noise is. In the novel direct conversion pixelated radiation detector utilizing a novel three dimensional semiconductor architecture, which is proposed in this work, the detector thickness is not limited by the substrate doping and the output capacitance is small and does not depend on the detector thickness. In addition, by incorporating an additional node to the novel three-dimensional semiconductor architecture it can be utilized as a high voltage transistor that can deliver current across high voltages. Furthermore, it is possible to connect a voltage difference of any size to the proposed novel three dimensional semiconductor architecture provided that it is thick enough—this is a novel feature that has not been previously possible for semiconductor

  6. A Compact 3D Omnidirectional Range Sensor of High Resolution for Robust Reconstruction of Environments

    Directory of Open Access Journals (Sweden)

    Roberto Marani

    2015-01-01

    Full Text Available In this paper, an accurate range sensor for the three-dimensional reconstruction of environments is designed and developed. Following the principles of laser profilometry, the device exploits a set of optical transmitters able to project a laser line on the environment. A high-resolution and high-frame-rate camera assisted by a telecentric lens collects the laser light reflected by a parabolic mirror, whose shape is designed ad hoc to achieve a maximum measurement error of 10 mm when the target is placed 3 m away from the laser source. Measurements are derived by means of an analytical model, whose parameters are estimated during a preliminary calibration phase. Geometrical parameters, analytical modeling and image processing steps are validated through several experiments, which indicate the capability of the proposed device to recover the shape of a target with high accuracy. Experimental measurements show Gaussian statistics, having standard deviation of 1.74 mm within the measurable range. Results prove that the presented range sensor is a good candidate for environmental inspections and measurements.

  7. 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions.

    Science.gov (United States)

    Wenzel, Carsten; Riefke, Björn; Gründemann, Stephan; Krebs, Alice; Christian, Sven; Prinz, Florian; Osterland, Marc; Golfier, Sven; Räse, Sebastian; Ansari, Nariman; Esner, Milan; Bickle, Marc; Pampaloni, Francesco; Mattheyer, Christian; Stelzer, Ernst H; Parczyk, Karsten; Prechtl, Stefan; Steigemann, Patrick

    2014-04-15

    Cancer cells in poorly vascularized tumor regions need to adapt to an unfavorable metabolic microenvironment. As distance from supplying blood vessels increases, oxygen and nutrient concentrations decrease and cancer cells react by stopping cell cycle progression and becoming dormant. As cytostatic drugs mainly target proliferating cells, cancer cell dormancy is considered as a major resistance mechanism to this class of anti-cancer drugs. Therefore, substances that target cancer cells in poorly vascularized tumor regions have the potential to enhance cytostatic-based chemotherapy of solid tumors. With three-dimensional growth conditions, multicellular tumor spheroids (MCTS) reproduce several parameters of the tumor microenvironment, including oxygen and nutrient gradients as well as the development of dormant tumor regions. We here report the setup of a 3D cell culture compatible high-content screening system and the identification of nine substances from two commercially available drug libraries that specifically target cells in inner MCTS core regions, while cells in outer MCTS regions or in 2D cell culture remain unaffected. We elucidated the mode of action of the identified compounds as inhibitors of the respiratory chain and show that induction of cell death in inner MCTS core regions critically depends on extracellular glucose concentrations. Finally, combinational treatment with cytostatics showed increased induction of cell death in MCTS. The data presented here shows for the first time a high-content based screening setup on 3D tumor spheroids for the identification of substances that specifically induce cell death in inner tumor spheroid core regions. This validates the approach to use 3D cell culture screening systems to identify substances that would not be detectable by 2D based screening in otherwise similar culture conditions.

  8. High-resolution 3D-GRE imaging of the abdomen using controlled aliasing acceleration technique - a feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    AlObaidy, Mamdoh; Ramalho, Miguel; Busireddy, Kiran K.R.; Liu, Baodong; Burke, Lauren M.; Altun, Ersan; Semelka, Richard C. [University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC (United States); Dale, Brian M. [Siemens Medical Solutions, MR Research and Development, Morrisville, NC (United States)

    2015-12-15

    To assess the feasibility of high-resolution 3D-gradient-recalled echo (GRE) fat-suppressed T1-weighted images using controlled aliasing acceleration technique (CAIPIRINHA-VIBE), and compare image quality and lesion detection to standard-resolution 3D-GRE images using conventional acceleration technique (GRAPPA-VIBE). Eighty-four patients (41 males, 43 females; age range: 14-90 years, 58.8 ± 15.6 years) underwent abdominal MRI at 1.5 T with CAIPIRINHA-VIBE [spatial resolution, 0.76 ± 0.04 mm] and GRAPPA-VIBE [spatial resolution, 1.17 ± 0.14 mm]. Two readers independently reviewed image quality, presence of artefacts, lesion conspicuity, and lesion detection. Kappa statistic was used to assess interobserver agreement. Wilcoxon signed-rank test was used for image qualitative pairwise comparisons. Logistic regression with post-hoc testing was used to evaluate statistical significance of lesions evaluation. Interobserver agreement ranged between 0.45-0.93. Pre-contrast CAIPIRINHA-VIBE showed significantly (p < 0.001) sharper images and lesion conspicuity with decreased residual aliasing, but more noise enhancement and inferior image quality. Post-contrast CAIPIRINHA-VIBE showed significantly (p < 0.001) sharper images and higher lesion conspicuity, with less respiratory motion and residual aliasing artefacts. Inferior fat-suppression was noticeable on CAIPIRINHA-VIBE sequences (p < 0.001). High in-plane resolution abdominal 3D-GRE fat-suppressed T1-weighted imaging using controlled-aliasing acceleration technique is feasible and yields sharper images compared to standard-resolution images using standard acceleration, with higher post-contrast image quality and trend for improved hepatic lesions detection. (orig.)

  9. Highly ordered large-scale neuronal networks of individual cells - toward single cell to 3D nanowire intracellular interfaces.

    Science.gov (United States)

    Kwiat, Moria; Elnathan, Roey; Pevzner, Alexander; Peretz, Asher; Barak, Boaz; Peretz, Hagit; Ducobni, Tamir; Stein, Daniel; Mittelman, Leonid; Ashery, Uri; Patolsky, Fernando

    2012-07-25

    The use of artificial, prepatterned neuronal networks in vitro is a promising approach for studying the development and dynamics of small neural systems in order to understand the basic functionality of neurons and later on of the brain. The present work presents a high fidelity and robust procedure for controlling neuronal growth on substrates such as silicon wafers and glass, enabling us to obtain mature and durable neural networks of individual cells at designed geometries. It offers several advantages compared to other related techniques that have been reported in recent years mainly because of its high yield and reproducibility. The procedure is based on surface chemistry that allows the formation of functional, tailormade neural architectures with a micrometer high-resolution partition, that has the ability to promote or repel cells attachment. The main achievements of this work are deemed to be the creation of a large scale neuronal network at low density down to individual cells, that develop intact typical neurites and synapses without any glia-supportive cells straight from the plating stage and with a relatively long term survival rate, up to 4 weeks. An important application of this method is its use on 3D nanopillars and 3D nanowire-device arrays, enabling not only the cell bodies, but also their neurites to be positioned directly on electrical devices and grow with registration to the recording elements underneath.

  10. Focus Variation - A New Technology for High Resolution Optical 3D Surface Metrology in the Micro- and Nanometer Range

    Science.gov (United States)

    Huber, O.

    2009-04-01

    Focus Variation - A New Technology for High Resolution Optical 3D Surface Metrology in the Micro- and Nanometer Range S. Scherer1, E. Cristea1, O. Huber1, A. Krenn1 1 ALICONA GmbH Graz, Austria The need for increasing accuracy is a characteristic of all geo-applications, and hence of the instruments contributing to obtaining relevant data. Small and fine sensors are being developed, measuring different parameters of our geosystem and requiring continuous validation and calibration. These sensors have often very small components (fine sensors able to sense dust, atmospheric water vapour characteristics, pressure change, gravimeters, satellite micro-components), showing complex topographies including steep flanks and having varying reflective properties. In order to get valid and reliable results, quality assurance of these instruments and sensors is required. The optical technology Focus-Variation, developed by Alicona and added in the latest draft of the upcoming ISO standard 25178, provides high resolution 3D surface metrology even at those complex topographies. The technique of Focus-Variation combines the small depth of focus of an optical system with vertical scanning to provide topographical and color information from the variation of focus. It is used for high-resolution optical 3D surface measurements. The traceable and repeatable measurement results are further being used for e.g. calibration and validation purposes. Some of the characteristics of the technology are: - Measurement of instruments / samples with steep flanks up to 80° - Measurement of materials with strongly varying reflection properties - Measurement of surfaces presenting fine (from 10nm) or strong roughness Here, we present the operating principle and possible applications of the optical 3D measurement system "InfiniteFocus", which is based on the technology of Focus-Variation. With the vertical resolution of up to 10nm, InfiniteFocus yields meaningful form and roughness measurements. The

  11. High-Resolution 3D Bathymetric Mapping for Small Streams Using Low-Altitude Aerial Photography

    Science.gov (United States)

    Dietrich, J. T.; Duffin, J.

    2015-12-01

    Geomorphic monitoring of river restoration projects is a critical component of measuring their success. In smaller streams, with depths less than 2 meters, one of the more difficult variables to map at high-resolution is bathymetry. In larger rivers, bathymetry can be measured with instruments like multi-beam sonar, bathymetric airborne LiDAR, or acoustic doppler current profilers (ADCP). However, these systems are often limited by their minimum operating depths, which makes them ineffective in shallow water. Remote sensing offers several potential solutions for collecting bathymetry, spectral depth mapping and photogrammetric measurement (e.g. Structure-from-Motion (SfM) multi-view photogrammetry). In this case study, we use SfM to produce both high-resolution above water topography and below water bathymetry for two reaches of a stream restoration project on the Middle Fork of the John Day River in eastern Oregon and one reach on the White River in Vermont. We collected low-allitude multispectral (RGB+NIR) aerial photography at all of the sites at altitudes of 30 to 50 meters. The SfM survey was georeferenced with RTK-GPS ground control points and the bathymetry was refraction-corrected using additional RTK-GPS sample points. The resulting raster data products have horizontal resolutions of ~4-8 centimeters for the topography and ~8-15 cm for the bathymetry. This methodology, like many fluvial remote sensing methods, will only work under ideal conditions (e.g. clear water), but it provides an additional tool for collecting high-resolution bathymetric datasets for geomorphic monitoring efforts.

  12. APEnet+: high bandwidth 3D torus direct network for petaflops scale commodity clusters

    CERN Document Server

    Ammendola, Roberto; Frezza, Ottorino; Cicero, Francesca Lo; Lonardo, Alessandro; Paolucci, Pier Stanislao; Rossetti, Davide; Salamon, Andrea; Salina, Gaetano; Simula, Francesco; Tosoratto, Laura; Vicini, Piero

    2011-01-01

    We describe herein the APElink+ board, a PCIe interconnect adapter featuring the latest advances in wire speed and interface technology plus hardware support for a RDMA programming model and experimental acceleration of GPU networking; this design allows us to build a low latency, high bandwidth PC cluster, the APEnet+ network, the new generation of our cost-effective, tens-of-thousands-scalable cluster network architecture. Some test results and characterization of data transmission of a complete testbench, based on a commercial development card mounting an Altera FPGA, are provided.

  13. A new ray-tracing scheme for 3D diffuse radiation transfer on highly parallel architectures

    OpenAIRE

    Tanaka, Satoshi; Yoshikawa, Kohji; Okamoto, Takashi; HASEGAWA, Kenji

    2014-01-01

    We present a new numerical scheme to solve the transfer of diffuse radiation on three-dimensional mesh grids which is efficient on processors with highly parallel architecture such as recently popular GPUs and CPUs with multi- and many-core architectures. The scheme is based on the ray-tracing method and the computational cost is proportional to $N_{\\rm m}^{5/3}$ where $N_{\\rm m}$ is the number of mesh grids, and is devised to compute the radiation transfer along each light-ray completely in ...

  14. APEnet+: high bandwidth 3D torus direct network for petaflops scale commodity clusters

    International Nuclear Information System (INIS)

    We describe herein the APElink+ board, a PCIe interconnect adapter featuring the latest advances in wire speed and interface technology plus hardware support for a RDMA programming model and experimental acceleration of GPU networking; this design allows us to build a low latency, high bandwidth PC cluster, the APEnet+ network, the new generation of our cost-effective, tens-of-thousands-scalable cluster network architecture. Some test results and characterization of data transmission of a complete testbench, based on a commercial development card mounting an Altera® FPGA, are provided.

  15. An Optimized Data Structure for High Throughput 3D Proteomics Data: mzRTree

    CERN Document Server

    Nasso, Sara; Tisiot, Francesco; Di Camillo, Barbara; Pietracaprina, Andrea; Toffolo, Gianna Maria

    2010-01-01

    As an emerging field, MS-based proteomics still requires software tools for efficiently storing and accessing experimental data. In this work, we focus on the management of LC-MS data, which are typically made available in standard XML-based portable formats. The structures that are currently employed to manage these data can be highly inefficient, especially when dealing with high-throughput profile data. LC-MS datasets are usually accessed through 2D range queries. Optimizing this type of operation could dramatically reduce the complexity of data analysis. We propose a novel data structure for LC-MS datasets, called mzRTree, which embodies a scalable index based on the R-tree data structure. mzRTree can be efficiently created from the XML-based data formats and it is suitable for handling very large datasets. We experimentally show that, on all range queries, mzRTree outperforms other known structures used for LC-MS data, even on those queries these structures are optimized for. Besides, mzRTree is also mor...

  16. 3-D high-speed imaging of volcanic bomb trajectory in basaltic explosive eruptions

    Science.gov (United States)

    Gaudin, D.; Taddeucci, J; Houghton, B. F.; Orr, Tim R.; Andronico, D.; Del Bello, E.; Kueppers, U.; Ricci, T.; Scarlato, P.

    2016-01-01

    Imaging, in general, and high speed imaging in particular are important emerging tools for the study of explosive volcanic eruptions. However, traditional 2-D video observations cannot measure volcanic ejecta motion toward and away from the camera, strongly hindering our capability to fully determine crucial hazard-related parameters such as explosion directionality and pyroclasts' absolute velocity. In this paper, we use up to three synchronized high-speed cameras to reconstruct pyroclasts trajectories in three dimensions. Classical stereographic techniques are adapted to overcome the difficult observation conditions of active volcanic vents, including the large number of overlapping pyroclasts which may change shape in flight, variable lighting and clouding conditions, and lack of direct access to the target. In particular, we use a laser rangefinder to measure the geometry of the filming setup and manually track pyroclasts on the videos. This method reduces uncertainties to 10° in azimuth and dip angle of the pyroclasts, and down to 20% in the absolute velocity estimation. We demonstrate the potential of this approach by three examples: the development of an explosion at Stromboli, a bubble burst at Halema'uma'u lava lake, and an in-flight collision between two bombs at Stromboli.

  17. 3D high-efficiency video coding for multi-view video and depth data.

    Science.gov (United States)

    Muller, Karsten; Schwarz, Heiko; Marpe, Detlev; Bartnik, Christian; Bosse, Sebastian; Brust, Heribert; Hinz, Tobias; Lakshman, Haricharan; Merkle, Philipp; Rhee, Franz Hunn; Tech, Gerhard; Winken, Martin; Wiegand, Thomas

    2013-09-01

    This paper describes an extension of the high efficiency video coding (HEVC) standard for coding of multi-view video and depth data. In addition to the known concept of disparity-compensated prediction, inter-view motion parameter, and inter-view residual prediction for coding of the dependent video views are developed and integrated. Furthermore, for depth coding, new intra coding modes, a modified motion compensation and motion vector coding as well as the concept of motion parameter inheritance are part of the HEVC extension. A novel encoder control uses view synthesis optimization, which guarantees that high quality intermediate views can be generated based on the decoded data. The bitstream format supports the extraction of partial bitstreams, so that conventional 2D video, stereo video, and the full multi-view video plus depth format can be decoded from a single bitstream. Objective and subjective results are presented, demonstrating that the proposed approach provides 50% bit rate savings in comparison with HEVC simulcast and 20% in comparison with a straightforward multi-view extension of HEVC without the newly developed coding tools. PMID:23715605

  18. Piezoresistive Sensor with High Elasticity Based on 3D Hybrid Network of Sponge@CNTs@Ag NPs.

    Science.gov (United States)

    Zhang, Hui; Liu, Nishuang; Shi, Yuling; Liu, Weijie; Yue, Yang; Wang, Siliang; Ma, Yanan; Wen, Li; Li, Luying; Long, Fei; Zou, Zhengguang; Gao, Yihua

    2016-08-31

    Pressure sensors with high elasticity are in great demand for the realization of intelligent sensing, but there is a need to develope a simple, inexpensive, and scalable method for the manufacture of the sensors. Here, we reported an efficient, simple, facile, and repeatable "dipping and coating" process to manufacture a piezoresistive sensor with high elasticity, based on homogeneous 3D hybrid network of carbon nanotubes@silver nanoparticles (CNTs@Ag NPs) anchored on a skeleton sponge. Highly elastic, sensitive, and wearable sensors are obtained using the porous structure of sponge and the synergy effect of CNTs/Ag NPs. Our sensor was also tested for over 2000 compression-release cycles, exhibiting excellent elasticity and cycling stability. Sensors with high performance and a simple fabrication process are promising devices for commercial production in various electronic devices, for example, sport performance monitoring and man-machine interfaces.

  19. Compressive Sensing in High-resolution 3D SAR Tomography of Urban Scenarios

    Directory of Open Access Journals (Sweden)

    Liao Ming-sheng

    2015-04-01

    Full Text Available In modern high resolution SAR data, due to the intrinsic side-looking geometry of SAR sensors, layover and foreshortening issues inevitably arise, especially in dense urban areas. SAR tomography provides a new way of overcoming these problems by exploiting the back-scattering property for each pixel. However, traditional non-parametric spectral estimators, e.g. Truncated Singular Value Decomposition (TSVD, are limited by their poor elevation resolution, which is not comparable to the azimuth and slant-range resolution. In this paper, the Compressive Sensing (CS approach using Basis Pursuit (BP and TWo-step Iterative Shrinkage/Thresholding (TWIST are introduced. Experimental studies with real spotlight-mode TerraSAR-X dataset are carried out using both BP and TWIST, to demonstrate the merits of compressive sensing approaches in terms of robustness, computational efficiency, and super-resolution capability.

  20. High resolution processing of 3D seismic data for thin coal seam in Guqiao coal mine

    Science.gov (United States)

    Li, Qiaoling; Peng, Suping; Zou, Guangui

    2015-04-01

    Accurate identification of small faults for coal seams is very important for coal-field exploration, which can greatly improve mining efficiency and safety. However, coal seams in China are mostly thin layers, ranging from 2-5 m. Moreover, the shallow coal seam with strong reflection forms a shield underneath thin coal seam which is only about 40 m deeper. This causes great difficulty in seismic processing and interpretation. The primary concern is to obtain high-resolution seismic image of underneath thin coal seam for mining safety. In this paper, field data is carefully analyzed and fit-for-purpose solutions are adopted in order to improve the quality of reprocessed data and resolution of target coal seam. Identification of small faults has been enhanced significantly.

  1. A 3-D miniaturized high selectivity bandpass filter in LTCC technology

    KAUST Repository

    Arabi, Eyad A.

    2014-01-01

    Transmission zeros are used to improve the roll-off factors of filters but as a consequence, the out-of-band rejection decreases. In this work, an LTCC filter design is presented which employs a series inductor (implemented as a via hole) to improve the out-of-band rejection by introducing a third transmission zero. The filter, designed for GPS band (1.57 GHz), has one of the smallest reported foot prints ((0.063×0.048×0.005)λg) and demonstrates the highest roll off factor (16.7 dB/100 MHz) for this band. With only four LTCC layers, the design is cost effective and thus highly suitable for miniaturized, ultra-thin system-on-package applications. © 2001-2012 IEEE.

  2. High-Temperature Cutoff Approximation of the 3D Kinetic Ising Model

    Institute of Scientific and Technical Information of China (English)

    ZHU JianYang; YANG ZhanRu

    2001-01-01

    A single-spin transition critical dynamics is used to investigate the three-dimensional kinetic Ising model on an anisotropic cubic lattice. We first derive the fundamental dynamical equations, and then linearize them by a cutoff approximation. We obtain the approximate solutions of the local magnetization and equal-time pair correlation function in zero field. In which the axial-decoupling terms γ1γ2, γ2γ3 and γ1γ3 as higher infinitesimal quantity are ignored, where γa = tanh(2kα) = tanh(2Jα/kβT) (α = 1,2,3). We think that it is reasonable as the temperature of the system is very high. The result of what we obtain in this paper can go back to the one-dimensional Glauber's theory as long as k2 = k3= 0.

  3. High-performance 3D waveguide architecture for astronomical pupil-remapping interferometry

    CERN Document Server

    Norris, Barnaby; Gross, Simon; Jovanovic, Nemanja; Stewart, Paul N; Charles, Ned; Lawrence, Jon S; Withford, Michael J; Tuthill, Peter

    2014-01-01

    The detection and characterisation of extra-solar planets is a major theme driving modern astronomy, with the vast majority of such measurements being achieved by Doppler radial-velocity and transit observations. Another technique -- direct imaging -- can access a parameter space that complements these methods, and paves the way for future technologies capable of detailed characterization of exoplanetary atmospheres and surfaces. However achieving the required levels of performance with direct imaging, particularly from ground-based telescopes which must contend with the Earth's turbulent atmosphere, requires considerable sophistication in the instrument and detection strategy. Here we demonstrate a new generation of photonic pupil-remapping devices which build upon the interferometric framework developed for the {\\it Dragonfly} instrument: a high contrast waveguide-based device which recovers robust complex visibility observables. New generation Dragonfly devices overcome problems caused by interference from...

  4. A novel high-order, entropy stable, 3D AMR MHD solver with guaranteed positive pressure

    Science.gov (United States)

    Derigs, Dominik; Winters, Andrew R.; Gassner, Gregor J.; Walch, Stefanie

    2016-07-01

    We describe a high-order numerical magnetohydrodynamics (MHD) solver built upon a novel non-linear entropy stable numerical flux function that supports eight travelling wave solutions. By construction the solver conserves mass, momentum, and energy and is entropy stable. The method is designed to treat the divergence-free constraint on the magnetic field in a similar fashion to a hyperbolic divergence cleaning technique. The solver described herein is especially well-suited for flows involving strong discontinuities. Furthermore, we present a new formulation to guarantee positivity of the pressure. We present the underlying theory and implementation of the new solver into the multi-physics, multi-scale adaptive mesh refinement (AMR) simulation code FLASH (http://flash.uchicago.edu)

  5. A Novel High-Order, Entropy Stable, 3D AMR MHD Solver with Guaranteed Positive Pressure

    CERN Document Server

    Derigs, Dominik; Gassner, Gregor J; Walch, Stefanie

    2016-01-01

    We describe a high-order numerical magnetohydrodynamics (MHD) solver built upon a novel non-linear entropy stable numerical flux function that supports eight travelling wave solutions. By construction the solver conserves mass, momentum, and energy and is entropy stable. The method is designed to treat the divergence-free constraint on the magnetic field in a similar fashion to a hyperbolic divergence cleaning technique. The solver described herein is especially well-suited for flows involving strong discontinuities. Furthermore, we present a new formulation to guarantee positivity of the pressure. We present the underlying theory and implementation of the new solver into the multi-physics, multi-scale adaptive mesh refinement (AMR) simulation code $\\texttt{FLASH}$ (http://flash.uchicago.edu). The accuracy, robustness and computational efficiency is demonstrated with a number of tests, including comparisons to available MHD implementations in $\\texttt{FLASH}$.

  6. High order spatial expansion for the method of characteristics applied to 3-D geometries

    International Nuclear Information System (INIS)

    The method of characteristics is an efficient and flexible technique to solve the neutron transport equation and has been extensively used in two-dimensional calculations because it permits to deal with complex geometries. However, because of a very fast increase in storage requirements and number of floating operations, its direct application to three-dimensional routine transport calculations it is not still possible. In this work we introduce and analyze several modifications aimed to reduce memory requirements and to diminish the computing burden. We explore high-order spatial approximation, the use of intermediary trajectory-dependent flux expansions and the possibility of dynamic trajectory reconstruction from local tracking for typed subdomains. (authors)

  7. Two-photon luminescence thermometry: towards 3D high-resolution thermal imaging of waveguides.

    Science.gov (United States)

    He, Ruiyun; Vázquez de Aldana, Javier Rodríguez; Pedrola, Ginés Lifante; Chen, Feng; Jaque, Daniel

    2016-07-11

    We report on the use of the Erbium-based luminescence thermometry to realize high resolution, three dimensional thermal imaging of optical waveguides. Proof of concept is demonstrated in a 980-nm laser pumped ultrafast laser inscribed waveguide in Er:Yb phosphate glass. Multi-photon microscopy images revealed the existence of well confined intra-waveguide temperature increments as large as 200 °C for moderate 980-nm pump powers of 120 mW. Numerical simulations and experimental data reveal that thermal loading can be substantially reduced if pump events are separated more than the characteristic thermal time that for the waveguides investigated is in the ms time scale. PMID:27410882

  8. Calorimetric approach for 3D dosimetry of high intensity therapeutic electron beams

    Science.gov (United States)

    Lamanna, E.; Fiorillo, A. S.; Vena, R.; Berdondini, A.; Bettuzzi, M.; Brancaccio, R.; Casali, F.; Morigi, M. P.; Bilokon, H.; Barca, G.; Castrovillari, F.; Siaka, Y. F. T.

    2009-12-01

    The technique of High Dose Rate Intra-Operative Radiation Therapy (HDR-IORT) consists in the delivery of irradiation immediately after the removal of a cancerous mass, where the same incision is used to focalize the radiation to the tumour bed. Given its particular characteristics, IORT requires dose measurements that are different from those requested in external radiotherapy treatments. The main reason lies in the fact that in this case a single high dose must be delivered to a target volume whose extension and depth will be determined directly during the operation. Because of this peculiar characteristics, until now there is not a dosimetric system able to detect the electron beam giving at once a realtime response and an extensive spatial measure of the absorbed dose. Within the framework of a research project of the INFN (Italian National Institute of Nuclear Physics), we proposed a new system to overcome the problems, Dosiort. The final set-up is a solid phantom having a density approximately 1 g/cm3 with sensitive layers of scintillating fibres at fixed positions in a calorimetric configuration for the containment of electrons of energy 4-12 MeV. The prototype will be able to define the physical and geometrical characteristics of the electron beam (energy, isotropy, homogeneity, etc) and to measure the parameters needed to select the energy, the intensity and the Monitor Units (MU) for the exposition: percentage Depth Dose; beam profiles; isodose curves; values of dose per MU. In this work we present the results obtained by using two orthogonal layers of the calorimetric phantom Dosiort, in particular we report the measurement of the dynamic range of the read-out system and the first qualitative study of the results which can be extracted from the measurements taken in a test beam.

  9. High-resolution direct 3D printed PLGA scaffolds: print and shrink

    International Nuclear Information System (INIS)

    Direct three-dimensional printing (3DP) produces the final part composed of the powder and binder used in fabrication. An advantage of direct 3DP is control over both the microarchitecture and macroarchitecture. Prints which use porogen incorporated in the powder result in high pore interconnectivity, uniform porosity, and defined pore size after leaching. The main limitations of direct 3DP for synthetic polymers are the use of organic solvents which can dissolve polymers used in most printheads and limited resolution due to unavoidable spreading of the binder droplet after contact with the powder. This study describes a materials processing strategy to eliminate the use of organic solvent during the printing process and to improve 3DP resolution by shrinking with a non-solvent plasticizer. Briefly, poly(lactic-co-glycolic acid) (PLGA) powder was prepared by emulsion solvent evaporation to form polymer microparticles. The printing powder was composed of polymer microparticles dry mixed with sucrose particles. After printing with a water-based liquid binder, the polymer microparticles were fused together to form a network by solvent vapor in an enclosed vessel. The sucrose is removed by leaching and the resulting scaffold is placed in a solution of methanol. The methanol acts as a non-solvent plasticizer and allows for polymer chain rearrangement and efficient packing of polymer chains. The resulting volumetric shrinkage is ∼80% at 90% methanol. A complex shape (honey-comb) was designed, printed, and shrunken to demonstrate isotropic shrinking with the ability to reach a final resolution of ∼400 μm. The effect of type of alcohol (i.e. methanol or ethanol), concentration of alcohol, and temperature on volumetric shrinking was studied. This study presents a novel materials processing strategy to overcome the main limitations of direct 3DP to produce high resolution PLGA scaffolds. (paper)

  10. Hydrogel Based 3-Dimensional (3D System for Toxicity and High-Throughput (HTP Analysis for Cultured Murine Ovarian Follicles.

    Directory of Open Access Journals (Sweden)

    Hong Zhou

    Full Text Available Various toxicants, drugs and their metabolites carry potential ovarian toxicity. Ovarian follicles, the functional unit of the ovary, are susceptible to this type of damage at all stages of their development. However, despite of the large scale of potential negative impacts, assays that study ovarian toxicity are limited. Exposure of cultured ovarian follicles to toxicants of interest served as an important tool for evaluation of toxic effects for decades. Mouse follicles cultured on the bottom of a culture dish continue to serve an important approach for mechanistic studies. In this paper, we demonstrated the usefulness of a hydrogel based 3-dimensional (3D mouse ovarian follicle culture as a tool to study ovarian toxicity in a different setup. The 3D in vitro culture, based on fibrin alginate interpenetrating network (FA-IPN, preserves the architecture of the ovarian follicle and physiological structure-function relationship. We applied the novel 3D high-throughput (HTP in vitro ovarian follicle culture system to study the ovotoxic effects of an anti-cancer drug, Doxorobucin (DXR. The fibrin component in the system is degraded by plasmin and appears as a clear circle around the encapsulated follicle. The degradation area of the follicle is strongly correlated with follicle survival and growth. To analyze fibrin degradation in a high throughput manner, we created a custom MATLAB® code that converts brightfield micrographs of follicles encapsulated in FA-IPN to binary images, followed by image analysis. We did not observe any significant difference between manually processed images to the automated MATLAB® method, thereby confirming that the automated program is suitable to measure fibrin degradation to evaluate follicle health. The cultured follicles were treated with DXR at concentrations ranging from 0.005 nM to 200 nM, corresponding to the therapeutic plasma levels of DXR in patients. Follicles treated with DXR demonstrated decreased

  11. Stress-Free Bonding Technology with Pyrex for Highly Integrated 3D Fluidic Microsystems

    Directory of Open Access Journals (Sweden)

    Florian Thoma

    2014-09-01

    Full Text Available In this article, a novel Pyrex reflow bonding technology is introduced which bonds two functional units made of silicon via a Pyrex reflow bonding process. The practical application demonstrated here is a precision dosing system that uses a mechanically actuated membrane micropump which includes passive membranes for fluid metering. To enable proper functioning after full integration, a technique for device assembly must be established which does not introduce additional stress into the system, but fulfills all other requirements, like pressure tolerance and chemical stability. This is achieved with a stress-free thermal bonding principle to bond Pyrex to silicon in a five-layer stack: after alignment, the silicon-Pyrex-silicon stack is heated to 730 °C. Above the glass transition temperature of 525 °C Pyrex exhibits viscoelastic behavior. This allows the glass layer to come into close mechanical contact with the upper and lower silicon layers. The high temperature and the close contact promotes the formation of a stable and reliable Si-O-Si bond, without introducing mechanical stress into the system, and without deformation upon cooling due to thermal mismatch.

  12. High-quality molybdenum disulfide nanosheets with 3D structure for electrochemical sensing

    Science.gov (United States)

    Yin, Aiping; Wei, Xuehong; Cao, Yexia; Li, Huiqing

    2016-11-01

    An electrochemical sensor has been developed for simultaneous detection of dopamine (DA), uric acid (UA) and ascorbic acid (AA) based on pure MoS2 nanosheets modified electrode. The MoS2 nanosheets are achieved via a facile strategy, one-step pyrolysis of ammonium molybdate, thiourea and layered g-C3N4 template. Possessing hierarchical porous structure and large pore volume as well as good conductivity, MoS2 nanosheets demonstrates significantly improved electrocatalytic activity toward oxidation of AA, DA, and UA. In the coexisting system, the peak separation of AA-DA, DA-UA and AA-UA is 208.3 mV, 128.0 mV and 336.3 mV, respectively, which is much larger than for other MoS2-based catalyst. On the basis of large potential separation and high current response, selective and sensitive simultaneous determination of AA, DA, and UA was successfully accomplished by DPV, displaying a linear response from 5 to 1200 μM, from 1 to 900 μM, and from 1 to 60 μM with a detection limit (S/N = 3) of 0.82, 0.15, and 0.06 μM. This work highlights the importance of Mo-edge sites of MoS2 and hierarchical porous structure for efficient catalysis.

  13. Geographies of High Frequency Trading

    DEFF Research Database (Denmark)

    Grindsted, Thomas Skou

    2016-01-01

    the valuation of time. As high frequency trading accelerates financial markets, the paper examines the spatio-temporalities of automated trading by the ways in which the speed of knowledge exploitation in financial markets is not only of interest, but also the expansion between different temporalities...

  14. Toward 3D graphene oxide gels based adsorbents for high-efficient water treatment via the promotion of biopolymers.

    Science.gov (United States)

    Cheng, Chong Sage; Deng, Jie; Lei, Bei; He, Ai; Zhang, Xiang; Ma, Lang; Li, Shuang; Zhao, Changsheng

    2013-12-15

    Recent studies showed that graphene oxide (GO) presented high adsorption capacities to various water contaminants. However, the needed centrifugation after adsorption and the potential biological toxicity of GO restricted its applications in wastewater treatment. In this study, a facile method is provided by using biopolymers to mediate and synthesize 3D GO based gels. The obtained hybrid gels present well-defined and interconnected 3D porous network, which allows the adsorbate molecules to diffuse easily into the adsorbent. The adsorption experiments indicate that the obtained porous GO-biopolymer gels can efficiently remove cationic dyes and heavy metal ions from wastewater. Methylene blue (MB) and methyl violet (MV), two cationic dyes, are chosen as model adsorbates to investigate the adsorption capability and desorption ratio; meanwhile, the influence of contacting time, initial concentration, and pH value on the adsorption capacity of the prepared GO-biopolymer gels are also studied. The GO-biopolymer gels displayed an adsorption capacity as high as 1100 mg/g for MB dye and 1350 mg/g for MV dye, respectively. Furthermore, the adsorption kinetics and isotherms of the MB were studied in details. The experimental data of MB adsorption fitted well with the pseudo-second-order kinetic model and the Langmuir isotherm, and the results indicated that the adsorption process was controlled by the intraparticle diffusion. Moreover, the adsorption data revealed that the porous GO-biopolymer gels showed good selective adsorbability to cationic dyes and metal ions.

  15. Petrophysical analysis of limestone rocks by nuclear logging and 3D high-resolution X-ray computed microtomography

    International Nuclear Information System (INIS)

    This study presents the pore-space system analysis of the 2-ITAB-1-RJ well cores, which were drilled in the Sao Jose do Itaborai Basin, in the state of Rio de Janeiro, Brasil. The analysis presented herein has been developed based on two techniques: nuclear logging and 3D high-resolution X-ray computed microtomography. Nuclear logging has been proven to be the technique that provides better quality and more quantitative information about the porosity using radioactive sources. The Density Gamma Probe and the Neutron Sonde used in this work provide qualitative information about bulk density variations and compensated porosity of the geological formation. The samples obtained from the well cores were analyzed by microtomography. The use of this technique in sedimentary rocks allows quantitative evaluation of pore system and generates high-resolution 3D images (∼microns order). The images and data obtained by microtomography were integrated with the response obtained by nuclear logging. The results obtained by these two techniques allow the understanding of the pore-size distribution and connectivity, as well as the porosity values. Both techniques are important and they complement each other.

  16. High resolution 3D MRI of mouse mammary glands with intra-ductal injection of contrast media.

    Science.gov (United States)

    Markiewicz, Erica; Fan, Xiaobing; Mustafi, Devkumar; Zamora, Marta; Roman, Brian B; Jansen, Sanaz A; Macleod, Kay; Conzen, Suzanne D; Karczmar, Gregory S

    2015-01-01

    The purpose of this study was to use high resolution three-dimensional (3D) magnetic resonance imaging (MRI) to study mouse mammary gland ductal architecture based on intra-ductal injection of contrast agents. Female FVB/N mice age 12-20 weeks (n=12), were used in this study. A 34G, 45° tip Hamilton needle with a 25μL Hamilton syringe was inserted into the tip of the nipple. Approximately 20-25μL of a Gadodiamide/Trypan blue/saline solution was injected slowly over one minute into the nipple and duct. To prevent washout of contrast media from ducts due to perfusion, and maximize the conspicuity of ducts on MRI, mice were sacrificed one minute after injection. High resolution 3D T1-weighted images were acquired on a 9.4T Bruker scanner after sacrifice to eliminate motion artifacts and reduce contrast media leakage from ducts. Trypan blue staining was well distributed throughout the ductal tree. MRI showed the mammary gland ductal structure clearly. In spoiled gradient echo T1-weighted images, the signal-to-noise ratio of regions identified as enhancing mammary ducts following contrast injection was significantly higher than that of muscle (pcontrast media (pcontrast agents to measure metabolism or target receptors in normal ducts and ducts with in situ cancers.

  17. High-temperature compatible 3D-integration processes for a vacuum-sealed CNT-based NEMS

    Science.gov (United States)

    Gueye, R.; Lee, S. W.; Akiyama, T.; Briand, D.; Roman, C.; Hierold, C.; de Rooij, N. F.

    2013-03-01

    A System-in-Package (SiP) concept for the 3D-integration of a Single Wall Carbon Nanotube (SWCNT) resonator with its CMOS driving electronics is presented. The key element of this advanced SiP is the monolithic 3D-integration of the MEMS with the CMOS electronics using Through Silicon Vias (TSVs) on an SOI wafer. This SiP includes: A glass cap vacuum-sealed to the main wafer using an eutectic bonding process: a low leak rate of 2.7 10-9 mbar•l/s was obtained; Platinum-TSVs, compatible with the SWCNT growth and release process; The TSVs were developed in a "via first" process and characterized at high-temperature — up to 850 °C. An ohmic contact between the Pt-metallization and the SOI silicon device layer was obtained; The driving CMOS electronic device is assembled to the MEMS using an Au stud bump technology. Keywords: System-in-Package (SiP), vacuum packaging, eutectic bonding, "via-first" TSVs, high-temperature platinum interconnects, ohmic contacts, Au-stud bumps assembly, CMOS electronics.

  18. High Resolution 3-D Finite-Volume Coastal Ocean Modeling in Lower Campbell River and Discovery Passage, British Columbia, Canada

    Directory of Open Access Journals (Sweden)

    Yuehua Lin

    2014-03-01

    Full Text Available The 3-D unstructured-grid, Finite-Volume Coastal Ocean Model (FVCOM was used to simulate the flows in Discovery Passage including the adjoining Lower Campbell River, British Columbia, Canada. Challenges in the studies include the strong tidal currents (e.g., up to 7.8 m/s in Seymour Narrows and tailrace discharges, small-scale topographic features and steep bottom slopes, and stratification affected by the Campbell River freshwater discharges. Two applications of high resolution 3-D FVCOM modeling were conducted. One is for the Lower Campbell River extending upstream as far as the John Hart Hydroelectric dam. The horizontal resolution varies from 0.27 m to 32 m in the unstructured triangular mesh to resolve the tailrace flow. The bottom elevation decreases ~14 m within the distance of ~1.4 km along the river. This pioneering FVCOM river modeling demonstrated a very good performance in simulating the river flow structures. The second application is to compute ocean currents immediately above the seabed along the present underwater electrical cable crossing routes across Discovery Passage. Higher resolution was used near the bottom with inter-layer spacing ranging from 0.125 to 0.0005 of total water depth. The model behaves very well in simulating the strong tidal currents in the area at high resolution in both the horizontal and vertical. One year maximum near bottom tidal current along the routes was then analyzed using the model results.

  19. 3D similarity-dissimilarity plot for high dimensional data visualization in the context of biomedical pattern classification.

    Science.gov (United States)

    Arif, Muhammad; Basalamah, Saleh

    2013-06-01

    In real life biomedical classification applications, it is difficult to visualize the feature space due to high dimensionality of the feature space. In this paper, we have proposed 3D similarity-dissimilarity plot to project the high dimensional space to a three dimensional space in which important information about the feature space can be extracted in the context of pattern classification. In this plot it is possible to visualize good data points (data points near to their own class as compared to other classes) and bad data points (data points far away from their own class) and outlier points (data points away from both their own class and other classes). Hence separation of classes can easily be visualized. Density of the data points near each other can provide some useful information about the compactness of the clusters within certain class. Moreover, an index called percentage of data points above the similarity-dissimilarity line (PAS) is proposed which is the fraction of data points above the similarity-dissimilarity line. Several synthetic and real life biomedical datasets are used to show the effectiveness of the proposed 3D similarity-dissimilarity plot.

  20. A compact single-camera system for high-speed, simultaneous 3-D velocity and temperature measurements.

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Louise; Sick, Volker; Frank, Jonathan H.

    2013-09-01

    The University of Michigan and Sandia National Laboratories collaborated on the initial development of a compact single-camera approach for simultaneously measuring 3-D gasphase velocity and temperature fields at high frame rates. A compact diagnostic tool is desired to enable investigations of flows with limited optical access, such as near-wall flows in an internal combustion engine. These in-cylinder flows play a crucial role in improving engine performance. Thermographic phosphors were proposed as flow and temperature tracers to extend the capabilities of a novel, compact 3D velocimetry diagnostic to include high-speed thermometry. Ratiometric measurements were performed using two spectral bands of laser-induced phosphorescence emission from BaMg2Al10O17:Eu (BAM) phosphors in a heated air flow to determine the optimal optical configuration for accurate temperature measurements. The originally planned multi-year research project ended prematurely after the first year due to the Sandia-sponsored student leaving the research group at the University of Michigan.

  1. Fully Automated One-Step Production of Functional 3D Tumor Spheroids for High-Content Screening.

    Science.gov (United States)

    Monjaret, François; Fernandes, Mathieu; Duchemin-Pelletier, Eve; Argento, Amelie; Degot, Sébastien; Young, Joanne

    2016-04-01

    Adoption of spheroids within high-content screening (HCS) has lagged behind high-throughput screening (HTS) due to issues with running complex assays on large three-dimensional (3D) structures.To enable multiplexed imaging and analysis of spheroids, different cancer cell lines were grown in 3D on micropatterned 96-well plates with automated production of nine uniform spheroids per well. Spheroids achieve diameters of up to 600 µm, and reproducibility was experimentally validated (interwell and interplate CV(diameter) imaging confirmed that micropatterned spheroids exhibit characteristic cell heterogeneity with distinct microregions. Furthermore, central necrosis appears at a consistent spheroid size, suggesting standardized growth.Using three reference compounds (fluorouracil, irinotecan, and staurosporine), we validated HT-29 micropatterned spheroids on an HCS platform, benchmarking against hanging-drop spheroids. Spheroid formation and imaging in a single plate accelerate assay workflow, and fixed positioning prevents structures from overlapping or sticking to the well wall, augmenting image processing reliability. Furthermore, multiple spheroids per well increase the statistical confidence sufficiently to discriminate compound mechanisms of action and generate EC50 values for endpoints of cell death, architectural change, and size within a single-pass read. Higher quality data and a more efficient HCS work chain should encourage integration of micropatterned spheroid models within fundamental research and drug discovery applications. PMID:26385905

  2. A high resolution hydrodynamic 3-D model simulation of the malta shelf area

    Directory of Open Access Journals (Sweden)

    A. F. Drago

    Full Text Available The seasonal variability of the water masses and transport in the Malta Channel and proximity of the Maltese Islands have been simulated by a high resolution (1.6 km horizontal grid on average, 15 vertical sigma layers eddy resolving primitive equation shelf model (ROSARIO-I. The numerical simulation was run with climatological forcing and includes thermohaline dynamics with a turbulence scheme for the vertical mixing coefficients on the basis of the Princeton Ocean Model (POM. The model has been coupled by one-way nesting along three lateral boundaries (east, south and west to an intermediate coarser resolution model (5 km implemented over the Sicilian Channel area. The fields at the open boundaries and the atmospheric forcing at the air-sea interface were applied on a repeating "perpetual" year climatological cycle.

    The ability of the model to reproduce a realistic circulation of the Sicilian-Maltese shelf area has been demonstrated. The skill of the nesting procedure was tested by model-modelc omparisons showing that the major features of the coarse model flow field can be reproduced by the fine model with additional eddy space scale components. The numerical results included upwelling, mainly in summer and early autumn, along the southern coasts of Sicily and Malta; a strong eastward shelf surface flow along shore to Sicily, forming part of the Atlantic Ionian Stream, with a presence throughout the year and with significant seasonal modulation, and a westward winter intensified flow of LIW centered at a depth of around 280 m under the shelf break to the south of Malta. The seasonal variability in the thermohaline structure of the domain and the associated large-scale flow structures can be related to the current knowledge on the observed hydrography of the area. The level of mesoscale resolution achieved by the model allowed the spatial and temporal evolution of the changing flow patterns, triggered by

  3. High-frequency solitons in media with induced scattering from damped low-frequency waves with nonuniform dispersion and nonlinearity

    Energy Technology Data Exchange (ETDEWEB)

    Aseeva, N. V., E-mail: vtyutin@hse.ru; Gromov, E. M.; Tyutin, V. V. [National Research University Higher School of Economics (Russian Federation)

    2015-12-15

    The dynamics of high-frequency field solitons is considered using the extended nonhomogeneous nonlinear Schrödinger equation with induced scattering from damped low-frequency waves (pseudoinduced scattering). This scattering is a 3D analog of the stimulated Raman scattering from temporal spatially homogeneous damped low-frequency modes, which is well known in optics. Spatial inhomogeneities of secondorder linear dispersion and cubic nonlinearity are also taken into account. It is shown that the shift in the 3D spectrum of soliton wavenumbers toward the short-wavelength region is due to nonlinearity increasing in coordinate and to decreasing dispersion. Analytic results are confirmed by numerical calculations.

  4. High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization.

    Science.gov (United States)

    Holden, Seamus J; Pengo, Thomas; Meibom, Karin L; Fernandez Fernandez, Carmen; Collier, Justine; Manley, Suliana

    2014-03-25

    We created a high-throughput modality of photoactivated localization microscopy (PALM) that enables automated 3D PALM imaging of hundreds of synchronized bacteria during all stages of the cell cycle. We used high-throughput PALM to investigate the nanoscale organization of the bacterial cell division protein FtsZ in live Caulobacter crescentus. We observed that FtsZ predominantly localizes as a patchy midcell band, and only rarely as a continuous ring, supporting a model of "Z-ring" organization whereby FtsZ protofilaments are randomly distributed within the band and interact only weakly. We found evidence for a previously unidentified period of rapid ring contraction in the final stages of the cell cycle. We also found that DNA damage resulted in production of high-density continuous Z-rings, which may obstruct cytokinesis. Our results provide a detailed quantitative picture of in vivo Z-ring organization.

  5. Development of a 3D Tissue Culture-Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine Kinases.

    NARCIS (Netherlands)

    Booij, T.H.; Klop, M.J.; Yan, K.; Szántai-Kis, C.; Szokol, B.; Orfi, L .; Water, van de B.; Keri, G.; Price, L.S.

    2016-01-01

    3D tissue cultures provide a more physiologically relevant context for the screening of compounds, compared with 2D cell cultures. Cells cultured in 3D hydrogels also show complex phenotypes, increasing the scope for phenotypic profiling. Here we describe a high-content screening platform that uses

  6. 3D printed sample holder for in-operando EPR spectroscopy on high temperature polymer electrolyte fuel cells.

    Science.gov (United States)

    Niemöller, Arvid; Jakes, Peter; Kayser, Steffen; Lin, Yu; Lehnert, Werner; Granwehr, Josef

    2016-08-01

    Electrochemical cells contain electrically conductive components, which causes various problems if such a cell is analyzed during operation in an EPR resonator. The optimum cell design strongly depends on the application and it is necessary to make certain compromises that need to be individually arranged. Rapid prototyping presents a straightforward option to implement a variable cell design that can be easily adapted to changing requirements. In this communication, it is demonstrated that sample containers produced by 3D printing are suitable for EPR applications, with a particular emphasis on electrochemical applications. The housing of a high temperature polymer electrolyte fuel cell (HT-PEFC) with a phosphoric acid doped polybenzimidazole membrane was prepared from polycarbonate by 3D printing. Using a custom glass Dewar, this fuel cell could be operated at temperatures up to 140°C in a standard EPR cavity. The carbon-based gas diffusion layer showed an EPR signal with a characteristic Dysonian line shape, whose evolution could be monitored in-operando in a non-invasive manner.

  7. Ultra-low-cost 3D gaze estimation: an intuitive high information throughput compliment to direct brain-machine interfaces.

    Science.gov (United States)

    Abbott, W W; Faisal, A A

    2012-08-01

    Eye movements are highly correlated with motor intentions and are often retained by patients with serious motor deficiencies. Despite this, eye tracking is not widely used as control interface for movement in impaired patients due to poor signal interpretation and lack of control flexibility. We propose that tracking the gaze position in 3D rather than 2D provides a considerably richer signal for human machine interfaces by allowing direct interaction with the environment rather than via computer displays. We demonstrate here that by using mass-produced video-game hardware, it is possible to produce an ultra-low-cost binocular eye-tracker with comparable performance to commercial systems, yet 800 times cheaper. Our head-mounted system has 30 USD material costs and operates at over 120 Hz sampling rate with a 0.5-1 degree of visual angle resolution. We perform 2D and 3D gaze estimation, controlling a real-time volumetric cursor essential for driving complex user interfaces. Our approach yields an information throughput of 43 bits s(-1), more than ten times that of invasive and semi-invasive brain-machine interfaces (BMIs) that are vastly more expensive. Unlike many BMIs our system yields effective real-time closed loop control of devices (10 ms latency), after just ten minutes of training, which we demonstrate through a novel BMI benchmark--the control of the video arcade game 'Pong'.

  8. 3D printed sample holder for in-operando EPR spectroscopy on high temperature polymer electrolyte fuel cells

    Science.gov (United States)

    Niemöller, Arvid; Jakes, Peter; Kayser, Steffen; Lin, Yu; Lehnert, Werner; Granwehr, Josef

    2016-08-01

    Electrochemical cells contain electrically conductive components, which causes various problems if such a cell is analyzed during operation in an EPR resonator. The optimum cell design strongly depends on the application and it is necessary to make certain compromises that need to be individually arranged. Rapid prototyping presents a straightforward option to implement a variable cell design that can be easily adapted to changing requirements. In this communication, it is demonstrated that sample containers produced by 3D printing are suitable for EPR applications, with a particular emphasis on electrochemical applications. The housing of a high temperature polymer electrolyte fuel cell (HT-PEFC) with a phosphoric acid doped polybenzimidazole membrane was prepared from polycarbonate by 3D printing. Using a custom glass Dewar, this fuel cell could be operated at temperatures up to 140 °C in a standard EPR cavity. The carbon-based gas diffusion layer showed an EPR signal with a characteristic Dysonian line shape, whose evolution could be monitored in-operando in a non-invasive manner.

  9. Experimental study on the confined 3D laminar flow past a square prism with a high blockage ratio

    International Nuclear Information System (INIS)

    Highlights: • Experimental study of the flow past a confined square section prism. • Flow regime is 3D and laminar. • Different regimes are identified depending on the Reynolds number. • Results could be used for practical engineering design purposes. -- Abstract: An experimental PIV study is presented that addresses the confined 3D laminar flow behaviour past a square prism. The Reynolds number (Re), based on prism cross-section height varies between 100 and 256. The channel aspect ratio is 1/1 and the blockage ratio is 1/2.5. This geometry is representative of a passive method to enhance mixing in otherwise highly ordered laminar channel flow. It is found that the lateral walls exert a strong effect on the flow behaviour with two main consequences: (a) the onset of vortex shedding is delayed to a Re in the vicinity of 170, as opposed to the unconfined case where the critical Re is reported to be between 50 and 60 and (b) transition from the steady closed recirculation bubble regime to the vortex shedding regime is not abrupt. In particular, there is a range of Re for which the closed recirculation bubble pulsates with increasing amplitude prior to the onset of the Karman street regime. The experimental results are supported by numerical computations, and the relation of the results with the practical design of engineering systems is also discussed

  10. 3D strain engineered self-rolled thin-film architecture for high-energy density lithium-ion batteries

    Science.gov (United States)

    Godbey, Griffin; Gong, Chen; Yu, Cynthia; Blythe, Clayton; Leite, Marina

    Recently, multiple 3D geometries have been implemented into energy storage devices (e . g . nanowire anodes and arrays of interdigitated rods) in order to better accommodate the large volume expansion experienced by the anode during lithiation and to increase the structure energy density. However, most approached structures are difficult to scale up. Here we show how self-rolled thin-films can maintain a high energy density and can potentially accommodate the volume expansion suffered by the anode. The self-rolled tubes are fabricated by physical deposition of the active layers, creating a stress gradient between thin-film stack due to differences in coefficient of thermal expansion. Upon a sacrificial layer removal, the thin-film rolls to relieve this built-in stress. We predict the final dimension of self-rolled battery tubes using known elastic properties of materials commonly used as the active layers of the device. We will discuss an appropriate figure-of-merit that defines how the winding process can ultimately affect the volumetric capacity of 3D self-rolled batteries.

  11. 3D Online Submicron Scale Observation of Mixed Metal Powder's Microstructure Evolution in High Temperature and Microwave Compound Fields

    Directory of Open Access Journals (Sweden)

    Dan Kang

    2014-01-01

    Full Text Available In order to study the influence on the mechanical properties caused by microstructure evolution of metal powder in extreme environment, 3D real-time observation of the microstructure evolution of Al-Ti mixed powder in high temperature and microwave compound fields was realized by using synchrotron radiation computerized topography (SR-CT technique; the spatial resolution was enhanced to 0.37 μm/pixel through the designed equipment and the introduction of excellent reconstruction method for the first time. The process of microstructure evolution during sintering was clearly distinguished from 2D and 3D reconstructed images. Typical sintering parameters such as sintering neck size, porosity, and particle size of the sample were presented for quantitative analysis of the influence on the mechanical properties and the sintering kinetics during microwave sintering. The neck size-time curve was obtained and the neck growth exponent was 7.3, which indicated that surface diffusion was the main diffusion mechanism; the reason was the eddy current loss induced by the external microwave fields providing an additional driving force for mass diffusion on the particle surface. From the reconstructed images and the curve of porosity and average particle size versus temperature, it was believed that the presence of liquid phase aluminum accelerated the densification and particle growth.

  12. 3D printed sample holder for in-operando EPR spectroscopy on high temperature polymer electrolyte fuel cells.

    Science.gov (United States)

    Niemöller, Arvid; Jakes, Peter; Kayser, Steffen; Lin, Yu; Lehnert, Werner; Granwehr, Josef

    2016-08-01

    Electrochemical cells contain electrically conductive components, which causes various problems if such a cell is analyzed during operation in an EPR resonator. The optimum cell design strongly depends on the application and it is necessary to make certain compromises that need to be individually arranged. Rapid prototyping presents a straightforward option to implement a variable cell design that can be easily adapted to changing requirements. In this communication, it is demonstrated that sample containers produced by 3D printing are suitable for EPR applications, with a particular emphasis on electrochemical applications. The housing of a high temperature polymer electrolyte fuel cell (HT-PEFC) with a phosphoric acid doped polybenzimidazole membrane was prepared from polycarbonate by 3D printing. Using a custom glass Dewar, this fuel cell could be operated at temperatures up to 140°C in a standard EPR cavity. The carbon-based gas diffusion layer showed an EPR signal with a characteristic Dysonian line shape, whose evolution could be monitored in-operando in a non-invasive manner. PMID:27323280

  13. A Dielectric-Filled Waveguide Antenna Element for 3D Imaging Radar in High Temperature and Excessive Dust Conditions

    Science.gov (United States)

    Xu, Ding; Li, Zhiping; Chen, Xianzhong; Wang, Zhengpeng; Wu, Jianhua

    2016-01-01

    Three-dimensional information of the burden surface in high temperature and excessive dust industrial conditions has been previously hard to obtain. This paper presents a novel microstrip-fed dielectric-filled waveguide antenna element which is resistant to dust and high temperatures. A novel microstrip-to-dielectric-loaded waveguide transition was developed. A cylinder and cuboid composite structure was employed at the terminal of the antenna element, which improved the return loss performance and reduced the size. The proposed antenna element was easily integrated into a T-shape multiple-input multiple-output (MIMO) imaging radar system and tested in both the laboratory environment and real blast furnace environment. The measurement results show that the proposed antenna element works very well in industrial 3D imaging radar. PMID:27556469

  14. The Addition of Noncondensable Gases into RELAP5-3D for Analysis of High Temperature Gas-Cooled Reactors

    International Nuclear Information System (INIS)

    Oxygen, carbon dioxide, and carbon monoxide have been added to the RELAP5-3D computer code as noncondensable gases to support analysis of high temperature gas-cooled reactors. Models of these gases are required to simulate the effects of air ingress on graphite oxidation following a loss-of-coolant accident. Correlations were developed for specific internal energy, thermal conductivity, and viscosity for each gas at temperatures up to 3000 K. The existing model for internal energy (a quadratic function of temperature) was not sufficiently accurate at these high temperatures and was replaced by a more general, fourth-order polynomial. The maximum deviation between the correlations and the underlying data was 2.2% for the specific internal energy and 7% for the specific heat capacity at constant volume. The maximum deviation in the transport properties was 4% for oxygen and carbon monoxide and 12% for carbon dioxide

  15. A Dielectric-Filled Waveguide Antenna Element for 3D Imaging Radar in High Temperature and Excessive Dust Conditions.

    Science.gov (United States)

    Xu, Ding; Li, Zhiping; Chen, Xianzhong; Wang, Zhengpeng; Wu, Jianhua

    2016-01-01

    Three-dimensional information of the burden surface in high temperature and excessive dust industrial conditions has been previously hard to obtain. This paper presents a novel microstrip-fed dielectric-filled waveguide antenna element which is resistant to dust and high temperatures. A novel microstrip-to-dielectric-loaded waveguide transition was developed. A cylinder and cuboid composite structure was employed at the terminal of the antenna element, which improved the return loss performance and reduced the size. The proposed antenna element was easily integrated into a T-shape multiple-input multiple-output (MIMO) imaging radar system and tested in both the laboratory environment and real blast furnace environment. The measurement results show that the proposed antenna element works very well in industrial 3D imaging radar. PMID:27556469

  16. True 3D kinematic analysis for slope instability assessment in the Siq of Petra (Jordan), from high resolution TLS

    Science.gov (United States)

    Gigli, Giovanni; Margottini, Claudio; Spizzichino, Daniele; Ruther, Heinz; Casagli, Nicola

    2016-04-01

    released, stratigraphic setting and tectonic activity can be recognized. As a consequence, rock-falls have been occurring, even recently, with unstable rock mass volumes ranging from 0.1 m3 up to over some hundreds m3. Slope instability, acceleration of crack deformation and consequent increasing of rock-fall hazard conditions, could threaten the safety of tourist as well as the integrity of the heritage. 3D surface model coming from Terrestrial Laser Scanner acquisitions was developed almost all over the site of Petra, including the Siq. Comprehensively, a point cloud of five billion points was generated making the site of Petra likely the largest scanned archaeological site in the word. As far as the Siq, the scanner was positioned on the path floor at intervals of not more than 10 meters from each station. The total number of scans in the Siq was 220 with an average point cloud interval of approximately 3 cm. Subsequently, for the definition of the main rockfall source areas, a spatial kinematic analysis for the whole Siq has been performed, by using discontinuity orientation data extracted from the point cloud by means of the software Diana. Orientation, number of sets, spacing/frequency, persistence, block size and scale dependent roughness was obtained combining fieldwork and automatic analysis. This kind of analysis is able to establish where a particular instability mechanism is kinematically feasible, given the geometry of the slope, the orientation of discontinuities and shear strength of the rock. The final outcome of this project was a detail landslide kinematic index map, reporting main potential instability mechanisms for a given area. The kinematic index was finally calibrated for each instability mechanism (plane failure; wedge failure; block toppling; flexural toppling) surveyed in the site. The latter is including the collapse occurred in May 2015, likely not producing any victim, in a sector clearly identified by the susceptibility maps produced by the

  17. High-Frequency Seafloor Acoustics

    CERN Document Server

    Jackson, Darrell R

    2007-01-01

    High-Frequency Seafloor Acoustics is the first book in a new series sponsored by the Office of Naval Research on the latest research in underwater acoustics. This exciting new title provides ready access to experimental data, theory, and models relevant to high-frequency seafloor acoustics and will be of interest to sonar engineers and researchers working in underwater acoustics. The physical characteristics of the seafloor affecting acoustic propagation and scattering are covered, including physical and geoacoustic properties and surface roughness. Current theories for acoustic propagation in sediments are presented along with corresponding models for reflection, scattering, and seafloor penetration. The main text is backed up by an extensive bibliography and technical appendices.

  18. Parallel phase-shifting digital holography and its application to high-speed 3D imaging of dynamic object

    Science.gov (United States)

    Awatsuji, Yasuhiro; Xia, Peng; Wang, Yexin; Matoba, Osamu

    2016-03-01

    Digital holography is a technique of 3D measurement of object. The technique uses an image sensor to record the interference fringe image containing the complex amplitude of object, and numerically reconstructs the complex amplitude by computer. Parallel phase-shifting digital holography is capable of accurate 3D measurement of dynamic object. This is because this technique can reconstruct the complex amplitude of object, on which the undesired images are not superimposed, form a single hologram. The undesired images are the non-diffraction wave and the conjugate image which are associated with holography. In parallel phase-shifting digital holography, a hologram, whose phase of the reference wave is spatially and periodically shifted every other pixel, is recorded to obtain complex amplitude of object by single-shot exposure. The recorded hologram is decomposed into multiple holograms required for phase-shifting digital holography. The complex amplitude of the object is free from the undesired images is reconstructed from the multiple holograms. To validate parallel phase-shifting digital holography, a high-speed parallel phase-shifting digital holography system was constructed. The system consists of a Mach-Zehnder interferometer, a continuous-wave laser, and a high-speed polarization imaging camera. Phase motion picture of dynamic air flow sprayed from a nozzle was recorded at 180,000 frames per second (FPS) have been recorded by the system. Also phase motion picture of dynamic air induced by discharge between two electrodes has been recorded at 1,000,000 FPS, when high voltage was applied between the electrodes.

  19. 3D processing on 6 in. high resistive SOI wafers: Fabrication of edgeless strip and pixel detectors

    International Nuclear Information System (INIS)

    An insight is given into the state-of-the-art 3D processing on 6 in. (150 mm) high resistivity silicon-on-insulator (SOI) wafers. The edgeless detector design offers some attractive properties for high-energy physics experiments and medical imaging studies, such as seamless tileability of the detectors with an inactive region width of about 10 μm. These detectors can be made very thin and the active edge avoids inhomogeneous electric fields and surface leakage currents. The paper summarizes the fabrication of edgeless detectors and the issues faced in the 3D processing on 6 in. SOI wafers. The fabrication process employed highly doped polysilicon filling in order to implement the active edges of the detector. Several planarization and ICP-etching steps were required. The layout had microstrip detectors with a pitch of 50 μm and sizes of 5x5 cm2 and 1x1 cm2, and Medipix2 compatible 1.4x1.4 cm2 pixel detectors. Also several test structures were fabricated. Electrical characterization of a 150-μm-thick edgeless diode showed low leakage currents, below 1 nA/cm2 at full depletion. The single-strip measurements showed leakage currents of about 10 pA/cm, regardless of the detector size. Low breakdown voltage of about 20 V was observed for several detectors. This might be caused by cracking of the detector edges following self-dicing. A simplified process flow for the fabrication of edgeless detectors is presented. The process is straightforward and fast because it excludes multiple ion coupled plasma (ICP)-etching steps, slow and wafer-damaging polysilicon filling and planarization steps. First images of the prototype are presented.

  20. 3D Animation Essentials

    CERN Document Server

    Beane, Andy

    2012-01-01

    The essential fundamentals of 3D animation for aspiring 3D artists 3D is everywhere--video games, movie and television special effects, mobile devices, etc. Many aspiring artists and animators have grown up with 3D and computers, and naturally gravitate to this field as their area of interest. Bringing a blend of studio and classroom experience to offer you thorough coverage of the 3D animation industry, this must-have book shows you what it takes to create compelling and realistic 3D imagery. Serves as the first step to understanding the language of 3D and computer graphics (CG)Covers 3D anim

  1. 3D video

    CERN Document Server

    Lucas, Laurent; Loscos, Céline

    2013-01-01

    While 3D vision has existed for many years, the use of 3D cameras and video-based modeling by the film industry has induced an explosion of interest for 3D acquisition technology, 3D content and 3D displays. As such, 3D video has become one of the new technology trends of this century.The chapters in this book cover a large spectrum of areas connected to 3D video, which are presented both theoretically and technologically, while taking into account both physiological and perceptual aspects. Stepping away from traditional 3D vision, the authors, all currently involved in these areas, provide th

  2. Single objective light-sheet microscopy for high-speed whole-cell 3D super-resolution.

    Science.gov (United States)

    Meddens, Marjolein B M; Liu, Sheng; Finnegan, Patrick S; Edwards, Thayne L; James, Conrad D; Lidke, Keith A

    2016-06-01

    We have developed a method for performing light-sheet microscopy with a single high numerical aperture lens by integrating reflective side walls into a microfluidic chip. These 45° side walls generate light-sheet illumination by reflecting a vertical light-sheet into the focal plane of the objective. Light-sheet illumination of cells loaded in the channels increases image quality in diffraction limited imaging via reduction of out-of-focus background light. Single molecule super-resolution is also improved by the decreased background resulting in better localization precision and decreased photo-bleaching, leading to more accepted localizations overall and higher quality images. Moreover, 2D and 3D single molecule super-resolution data can be acquired faster by taking advantage of the increased illumination intensities as compared to wide field, in the focused light-sheet. PMID:27375939

  3. Influence of ultrasound power on acoustic streaming and micro-bubbles formations in a low frequency sono-reactor: mathematical and 3D computational simulation.

    Science.gov (United States)

    Sajjadi, Baharak; Raman, Abdul Aziz Abdul; Ibrahim, Shaliza

    2015-05-01

    This paper aims at investigating the influence of ultrasound power amplitude on liquid behaviour in a low-frequency (24 kHz) sono-reactor. Three types of analysis were employed: (i) mechanical analysis of micro-bubbles formation and their activities/characteristics using mathematical modelling. (ii) Numerical analysis of acoustic streaming, fluid flow pattern, volume fraction of micro-bubbles and turbulence using 3D CFD simulation. (iii) Practical analysis of fluid flow pattern and acoustic streaming under ultrasound irradiation using Particle Image Velocimetry (PIV). In mathematical modelling, a lone micro bubble generated under power ultrasound irradiation was mechanistically analysed. Its characteristics were illustrated as a function of bubble radius, internal temperature and pressure (hot spot conditions) and oscillation (pulsation) velocity. The results showed that ultrasound power significantly affected the conditions of hotspots and bubbles oscillation velocity. From the CFD results, it was observed that the total volume of the micro-bubbles increased by about 4.95% with each 100 W-increase in power amplitude. Furthermore, velocity of acoustic streaming increased from 29 to 119 cm/s as power increased, which was in good agreement with the PIV analysis.

  4. High-resolution 3D surface displacements from 2004 - 2012 at Santorini volcano, Greece measured by LiDAR-differencing

    Science.gov (United States)

    Parks, M.; Pyle, D. M.; Nissen, E.; Mather, T. A.; Raptakis, C.; Nomikou, P.

    2012-12-01

    In January 2011 Santorini volcano entered a period of unrest characterised by earthquake swarms and caldera-wide uplift. Interferometric Synthetic Aperture Radar (InSAR) measurements indicate vertical motions of 8 - 14 cm across the central volcanic island of Nea Kameni since the onset of unrest. In April 2004, a NERC funded Airborne Research and Survey Facility (ARSF) flight acquired high-resolution (1m per pixel) light detection and ranging laser radar (LiDAR) data over the central volcanic islands of Nea Kameni and Palea Kameni. This survey was repeated in May 2012 to provide an updated digital elevation model (DEM). We apply a new method of differencing pre- and post- deformation LiDAR point clouds using the Iterative Closest Point (ICP) algorithm to produce a high-resolution grid of 3D surface displacements from 2004 - 2012. The 2004 ("source") and 2012 ("target") point clouds are first split into square subsets ("windows") and the displacement for each window is determined by iterating three steps: (1) identifying closest point pairs; (2) calculating the translation and rotation required that best aligns the paired points; (3) applying this transformation to the source cloud. The surface displacement map spans both a period of slow subsidence (from 2004 - 2010), and a subsequent period of inflation (from 2011 - 2012). We shall compare our results with those obtained from simple DEM elevation differencing and from InSAR. To our knowledge, this is the first application of the ICP technique to measuring volcanic deformation. This approach may be implemented at other volcanoes to monitor 3D surface displacements during periods of unrest.

  5. Commissioning of a 3D image-based treatment planning system for high-dose-rate brachytherapy of cervical cancer.

    Science.gov (United States)

    Kim, Yongbok; Modrick, Joseph M; Pennington, Edward C; Kim, Yusung

    2016-01-01

    The objective of this work is to present commissioning procedures to clinically implement a three-dimensional (3D), image-based, treatment-planning system (TPS) for high-dose-rate (HDR) brachytherapy (BT) for gynecological (GYN) cancer. The physical dimensions of the GYN applicators and their values in the virtual applicator library were varied by 0.4 mm of their nominal values. Reconstruction uncertainties of the titanium tandem and ovoids (T&O) were less than 0.4 mm on CT phantom studies and on average between 0.8-1.0 mm on MRI when compared with X-rays. In-house software, HDRCalculator, was developed to check HDR plan parameters such as independently verifying active tandem or cylinder probe length and ovoid or cylinder size, source calibration and treatment date, and differences between average Point A dose and prescription dose. Dose-volume histograms were validated using another independent TPS. Comprehensive procedures to commission volume optimization algorithms and process in 3D image-based planning were presented. For the difference between line and volume optimizations, the average absolute differences as a percentage were 1.4% for total reference air KERMA (TRAK) and 1.1% for Point A dose. Volume optimization consistency tests between versions resulted in average absolute differences in 0.2% for TRAK and 0.9 s (0.2%) for total treatment time. The data revealed that the optimizer should run for at least 1 min in order to avoid more than 0.6% dwell time changes. For clinical GYN T&O cases, three different volume optimization techniques (graphical optimization, pure inverse planning, and hybrid inverse optimization) were investigated by comparing them against a conventional Point A technique. End-to-end testing was performed using a T&O phantom to ensure no errors or inconsistencies occurred from imaging through to planning and delivery. The proposed commissioning procedures provide a clinically safe implementation technique for 3D image-based TPS for HDR

  6. 3D Bridged Carbon Nanoring/Graphene Hybrid Paper as a High-Performance Lateral Heat Spreader.

    Science.gov (United States)

    Zhang, Jianwei; Shi, Gang; Jiang, Cai; Ju, Su; Jiang, Dazhi

    2015-12-01

    Graphene paper (GP) has attracted great attention as a heat dissipation material due to its unique thermal transfer property exceeding the limit of graphite. However, the relatively poor thermal transfer properties in the normal direction of GP restricts its wider applications in thermal management. In this work, a 3D bridged carbon nanoring (CNR)/graphene hybrid paper is constructed by the intercalation of polymer carbon source and metal catalyst particles, and the subsequent in situ growth of CNRs in the confined intergallery spaces between graphene sheets through thermal annealing. Further investigation demonstrates that the CNRs are covalently bonded to the graphene sheets and highly improve the thermal transport in the normal direction of the CNR/graphene hybrid paper. This full-carbon architecture shows excellent heat dissipation ability and is much more efficient in removing hot spots than the reduced GP without CNR bridges. This highly thermally conductive CNR/graphene hybrid paper can be easily integrated into next generation commercial high-power electronics and stretchable/foldable devices as high-performance lateral heat spreader materials. This full-carbon architecture also has a great potential in acting as electrodes in supercapacitors or hydrogen storage devices due to the high surface area. PMID:26476622

  7. Crust Uppermost Mantle Structure beneath Eastern Asia: Progress towards a Uniform, Tightly Constrained, High Resolution 3-D Model

    Science.gov (United States)

    Shen, W.; Ritzwoller, M. H.; Zheng, Y.; Lin, F. C.; Kim, Y.; Ning, J.; Kang, D.; Feng, L.; Wiens, D. A.

    2015-12-01

    In the past decade, large and dense seismic arrays have been deployed across much of eastern Asia (e.g., the "CEArray" and the "China Array" deployed by the China Earthquake Administration (CEA), the NECESS Array deployed collaboratively by China, Japan and the US, Korean Seismic Network, KNET and other networks in Japan, and historical PASSCAL installations), which have been used to produce increasingly well resolved models of the crust and uppermost mantle at different length scales. These models, however, do not cover eastern Asia uniformly. In this presentation, we report on an effort to generate a uniform high resolution 3-D model of the crust and uppermost mantle beneath eastern Asia using state-of-art surface wave and body wave inversion techniques. Highlights of this effort include: 1) We collect ambient noise cross-correlations using more than 1,800 seismic stations from multiple seismic arrays in this area and perform uniform surface wave tomography for the study area. 2) We collect P-wave receiver functions for over 1,000 stations and Rayleigh wave H/V ratio measurements for over 200 stations in this area. 3) We adopt a Bayesian Monte Carlo inversion to the Rayleigh wave dispersion maps and produce a uniform 3-D model with uncertainties of the crust and uppermost mantle. 4) In the areas where receiver functions and/or Rayleigh wave H/V ratios are collected, we replace the surface wave inversion by a joint inversion of surface waves and these seismic observables. The resulting model displays a great variety and considerable richness of geological and tectonic features in the crust and in the uppermost mantle which we summarize and discuss with focus on the relationship between the observed crustal variations and tectonic/geological boundaries and lithospheric modifications associated with volcanism in Northeast China.

  8. A High-resolution 3D Geodynamical Model of the Present-day India-Asia Collision System

    Science.gov (United States)

    Kaus, B.; Baumann, T.

    2015-12-01

    We present a high-resolution, 3D geodynamic model of the present-day India-Asia collision system. The model is separated into multiple tectonic blocks, for which we estimate the first order rheological properties and the impact on the dynamics of the collision system. This is done by performing systematic simulations with different rheologies to minimize the misfit to observational constraints such as the GPS-velocity field. The simulations are performed with the parallel staggered grid FD code LaMEM using a numerical resolution of at least 512x512x256 cells to resolve dynamically important shear zones reasonably well. A fundamental part of this study is the reconstruction of the 3D present-day geometry of Tibet and the adjacent regions. Our interpretations of crust and mantle lithosphere geometry are jointly based on a globally available shear wave tomography (Schaeffer and Lebedev, 2013) and the Crust 1.0 model (Laske et al. http://igppweb.ucsd.edu/~gabi/crust1.html). We regionally refined and modified our interpretations based on seismicity distributions and focal mechanisms and incorporated regional receiver function studies to improve the accuracy of the Moho in particular. Results suggest that we can identify at least one "best-fit" solution in terms of rheological model properties that reproduces the observed velocity field reasonably well, including the strong rotation of the GPS velocity around the eastern syntax of the Himalaya. We also present model co-variances to illustrate the trade-offs between the rheological model parameters, their respective uncertainties, and the model fit. Schaeffer, A.J., Lebedev, S., 2013. Global shear speed structure of the upper mantle and transition zone. Geophysical Journal International 194, 417-449. doi:10.1093/gji/ggt095

  9. Sea level history in 3D: Data acquisition and processing for an ultra-high resolution MCS survey across IODP Expedition 313 drillsite

    Science.gov (United States)

    Nedimovic, M. R.; Mountain, G. S.; Austin, J. A., Jr.; Fulthorpe, C.; Aali, M.; Baldwin, K.; Bhatnagar, T.; Johnson, C.; Küçük, H. M.; Newton, A.; Stanley, J.

    2015-12-01

    In June-July 2015, we acquired the first 3D/2D hybrid (short/long streamer) multichannel seismic (MCS) reflection dataset. These data were collected simultaneously across IODP Exp. 313 drillsites, off New Jersey, using R/V Langsethand cover ~95% of the planned 12x50 km box. Despite the large survey area, the lateral and vertical resolution for the 3D dataset is almost a magnitude of order higher than for data gathered for standard petroleum exploration. Such high-resolution was made possible by collection of common midpoint (CMP) lines whose combined length is ~3 times the Earth's circumference (~120,000 profile km) and a source rich in high-frequencies. We present details on the data acquisition, ongoing data analysis, and preliminary results. The science driving this project is presented by Mountain et al. The 3D component of this innovative survey used an athwartship cross cable, extended laterally by 2 barovanes roughly 357.5 m apart and trailed by 24 50-m P-Cables spaced ~12.5 m with near-trace offset of 53 m. Each P-Cable had 8 single hydrophone groups spaced at 6.25 m for a total of 192 channels. Record length was 4 s and sample rate 0.5 ms, with no low cut and an 824 Hz high cut filter. We ran 77 sail lines spaced ~150 m. Receiver locations were determined using 2 GPS receivers mounted on floats and 2 compasses and depth sensors per streamer. Streamer depths varied from 2.1 to 3.7 m. The 2D component used a single 3 km streamer, with 240 9-hydrophone groups spaced at 12.5 m, towed astern with near-trace offset of 229 m. The record length was 4 s and sample rate 0.5 ms, with low cut filter at 2 Hz and high cut at 412 Hz. Receiver locations were recorded using GPS at the head float and tail buoy, combined with 12 bird compasses spaced ~300 m. Nominal streamer depth was 4.5 m. The source for both systems was a 700 in3 linear array of 4 Bolt air guns suspended at 4.5 m towing depth, 271.5 m behind the ship's stern. Shot spacing was 12.5 m. Data analysis to

  10. High-frequency magnetic components

    CERN Document Server

    Kazimierczuk, Marian K

    2013-01-01

    A unique text on the theory and design fundaments of inductors and transformers, updated with more coverage on the optimization of magnetic devices and many new design examples The first edition is popular among a very broad audience of readers in different areas of engineering and science. This book covers the theory and design techniques of the major types of high-frequency power inductors and transformers for a variety of applications, including switching-mode power supplies (SMPS) and resonant dc-to-ac power inverters and dc-to-dc power converters. It describes eddy-current phenomena (su

  11. A Novel 2D Image Compression Algorithm Based on Two Levels DWT and DCT Transforms with Enhanced Minimize-Matrix-Size Algorithm for High Resolution Structured Light 3D Surface Reconstruction

    Science.gov (United States)

    Siddeq, M. M.; Rodrigues, M. A.

    2015-09-01

    Image compression techniques are widely used on 2D image 2D video 3D images and 3D video. There are many types of compression techniques and among the most popular are JPEG and JPEG2000. In this research, we introduce a new compression method based on applying a two level discrete cosine transform (DCT) and a two level discrete wavelet transform (DWT) in connection with novel compression steps for high-resolution images. The proposed image compression algorithm consists of four steps. (1) Transform an image by a two level DWT followed by a DCT to produce two matrices: DC- and AC-Matrix, or low and high frequency matrix, respectively, (2) apply a second level DCT on the DC-Matrix to generate two arrays, namely nonzero-array and zero-array, (3) apply the Minimize-Matrix-Size algorithm to the AC-Matrix and to the other high-frequencies generated by the second level DWT, (4) apply arithmetic coding to the output of previous steps. A novel decompression algorithm, Fast-Match-Search algorithm (FMS), is used to reconstruct all high-frequency matrices. The FMS-algorithm computes all compressed data probabilities by using a table of data, and then using a binary search algorithm for finding decompressed data inside the table. Thereafter, all decoded DC-values with the decoded AC-coefficients are combined in one matrix followed by inverse two levels DCT with two levels DWT. The technique is tested by compression and reconstruction of 3D surface patches. Additionally, this technique is compared with JPEG and JPEG2000 algorithm through 2D and 3D root-mean-square-error following reconstruction. The results demonstrate that the proposed compression method has better visual properties than JPEG and JPEG2000 and is able to more accurately reconstruct surface patches in 3D.

  12. Investigating particle phase velocity in a 3D spouted bed by a novel fiber high speed photography method

    Science.gov (United States)

    Qian, Long; Lu, Yong; Zhong, Wenqi; Chen, Xi; Ren, Bing; Jin, Baosheng

    2013-07-01

    A novel fiber high speed photography method has been developed to measure particle phase velocity in a dense gas-solid flow. The measurement system mainly includes a fiber-optic endoscope, a high speed video camera, a metal halide light source and a powerful computer with large memory. The endoscope which could be inserted into the reactors is used to form motion images of particles within the measurement window illuminated by the metal halide lamp. These images are captured by the high speed video camera and processed through a series of digital image processing algorithms, such as calibration, denoising, enhancement and binarization in order to improve the image quality. Then particles' instantaneous velocity is figured out by tracking each particle in consecutive frames. Particle phase velocity is statistically calculated according to the probability of particle velocity in each frame within a time period. This system has been applied to the investigation of particles fluidization characteristics in a 3D spouted bed. The experimental results indicate that the particle fluidization feature in the region investigated could be roughly classified into three sections by particle phase vertical velocity and the boundary between the first section and the second is the surface where particle phase velocity tends to be 0, which is in good agreement with the results published in other literature.

  13. 3D-CFD-simulation of melting processes in a high-speed-extruder with solid-melt-separation

    Science.gov (United States)

    Karrenberg, G.; Wortberg, J.

    2014-05-01

    This paper deals with the development of the so called High-Speed-S-Truder. The alternative extrusion concept uses a special plastification sleeve with hundreds of bores surrounding the screw to separate the emerging melt from solid material in the screw channel. To analyze and improve the complex fluid flow in this process CFD-simulations are used. However, the ability of simulating the flow as well as the plastification process is yet not given in any CFD-software. Thus an approach for 3D-CFDsimulations of melting polymeric materials in extrusion processes has been developed. A new material model enables to differ between solid phase and fluid phase in dependence of temperature in just one set of property descriptions. Hence it becomes possible to simulate melting in a single fluid domain without presupposing any melting mechanism. Therefore the model is universally applicable and can be used for the simulation of ordinary extrusion processes under high speed conditions as well as for the investigation and improvement of the melting mechanism in the High-Speed-S-Truder.

  14. High-resolution X-ray CT for 3D petrography of ferruginous sandstone for an investigation of building stone decay.

    Science.gov (United States)

    Cnudde, Veerle; Dewanckele, Jan; Boone, Matthieu; de Kock, Tim; Boone, Marijn; Brabant, Loes; Dusar, Michiel; de Ceukelaire, Marleen; de Clercq, Hilde; Hayen, Roald; Jacobs, Patric

    2011-11-01

    Diestian ferruginous sandstone has been used as the dominant building stone for monuments in the Hageland, a natural landscape in east-central Belgium. Like all rocks, this stone type is sensitive to weathering. Case hardening was observed in combination with blackening of the exterior parts of the dressed stones. To determine the 3D petrography and to identify the structural differences between the exterior and interior parts, X-ray computed tomography was used in combination with more traditional research techniques like optical microscopy and scanning electron microscopy. The 3D characterization of the ferruginous sandstone was performed with a high-resolution X-ray CT scanner (www.ugct.ugent.be) in combination with the flexible 3D analysis software Morpho+, which provides the necessary petrophysical parameters of the scanned samples in 3D. Besides providing the required 3D parameters like porosity, pore-size distribution, grain size, grain orientation, and surface analysis, the results of the 3D analysis can also be visualized, which enables to understand and interpret the analysis results in a straightforward way. The complementarities between high-quality X-ray CT images and flexible 3D software and its relation with the more traditional microscopical research techniques are opening up new gateways in the study of weathering processes of natural building stones.

  15. Scalable, incremental learning with MapReduce parallelization for cell detection in high-resolution 3D microscopy data

    KAUST Repository

    Sung, Chul

    2013-08-01

    Accurate estimation of neuronal count and distribution is central to the understanding of the organization and layout of cortical maps in the brain, and changes in the cell population induced by brain disorders. High-throughput 3D microscopy techniques such as Knife-Edge Scanning Microscopy (KESM) are enabling whole-brain survey of neuronal distributions. Data from such techniques pose serious challenges to quantitative analysis due to the massive, growing, and sparsely labeled nature of the data. In this paper, we present a scalable, incremental learning algorithm for cell body detection that can address these issues. Our algorithm is computationally efficient (linear mapping, non-iterative) and does not require retraining (unlike gradient-based approaches) or retention of old raw data (unlike instance-based learning). We tested our algorithm on our rat brain Nissl data set, showing superior performance compared to an artificial neural network-based benchmark, and also demonstrated robust performance in a scenario where the data set is rapidly growing in size. Our algorithm is also highly parallelizable due to its incremental nature, and we demonstrated this empirically using a MapReduce-based implementation of the algorithm. We expect our scalable, incremental learning approach to be widely applicable to medical imaging domains where there is a constant flux of new data. © 2013 IEEE.

  16. A simple and high-resolution stereolithography-based 3D bioprinting system using visible light crosslinkable bioinks.

    Science.gov (United States)

    Wang, Zongjie; Abdulla, Raafa; Parker, Benjamin; Samanipour, Roya; Ghosh, Sanjoy; Kim, Keekyoung

    2015-01-01

    Bioprinting is a rapidly developing technique for biofabrication. Because of its high resolution and the ability to print living cells, bioprinting has been widely used in artificial tissue and organ generation as well as microscale living cell deposition. In this paper, we present a low-cost stereolithography-based bioprinting system that uses visible light crosslinkable bioinks. This low-cost stereolithography system was built around a commercial projector with a simple water filter to prevent harmful infrared radiation from the projector. The visible light crosslinking was achieved by using a mixture of polyethylene glycol diacrylate (PEGDA) and gelatin methacrylate (GelMA) hydrogel with eosin Y based photoinitiator. Three different concentrations of hydrogel mixtures (10% PEG, 5% PEG + 5% GelMA, and 2.5% PEG + 7.5% GelMA, all w/v) were studied with the presented systems. The mechanical properties and microstructure of the developed bioink were measured and discussed in detail. Several cell-free hydrogel patterns were generated to demonstrate the resolution of the solution. Experimental results with NIH 3T3 fibroblast cells show that this system can produce a highly vertical 3D structure with 50 μm resolution and 85% cell viability for at least five days. The developed system provides a low-cost visible light stereolithography solution and has the potential to be widely used in tissue engineering and bioengineering for microscale cell patterning. PMID:26696527

  17. A simple and high-resolution stereolithography-based 3D bioprinting system using visible light crosslinkable bioinks.

    Science.gov (United States)

    Wang, Zongjie; Abdulla, Raafa; Parker, Benjamin; Samanipour, Roya; Ghosh, Sanjoy; Kim, Keekyoung

    2015-12-22

    Bioprinting is a rapidly developing technique for biofabrication. Because of its high resolution and the ability to print living cells, bioprinting has been widely used in artificial tissue and organ generation as well as microscale living cell deposition. In this paper, we present a low-cost stereolithography-based bioprinting system that uses visible light crosslinkable bioinks. This low-cost stereolithography system was built around a commercial projector with a simple water filter to prevent harmful infrared radiation from the projector. The visible light crosslinking was achieved by using a mixture of polyethylene glycol diacrylate (PEGDA) and gelatin methacrylate (GelMA) hydrogel with eosin Y based photoinitiator. Three different concentrations of hydrogel mixtures (10% PEG, 5% PEG + 5% GelMA, and 2.5% PEG + 7.5% GelMA, all w/v) were studied with the presented systems. The mechanical properties and microstructure of the developed bioink were measured and discussed in detail. Several cell-free hydrogel patterns were generated to demonstrate the resolution of the solution. Experimental results with NIH 3T3 fibroblast cells show that this system can produce a highly vertical 3D structure with 50 μm resolution and 85% cell viability for at least five days. The developed system provides a low-cost visible light stereolithography solution and has the potential to be widely used in tissue engineering and bioengineering for microscale cell patterning.

  18. Improvement of 3D Scanner

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The disadvantage remaining in 3D scanning system and its reasons are discussed. A new host-and-slave structure with high speed image acquisition and processing system is proposed to quicken the image processing and improve the performance of 3D scanning system.

  19. Synthesis of 3D structured graphene as a high performance catalyst support for methanol electro-oxidation

    Science.gov (United States)

    Li, Yecheng; Zhang, Lei; Hu, Zhuofeng; Yu, Jimmy C.

    2015-06-01

    A simple process for preparing 3D structured graphene (3D-G) by a solution combustion method is reported. The product was deposited with platinum and used for methanol electro-oxidation. The catalyst shows a considerable enhancement in both the activity and stability towards methanol electro-oxidation reaction. Characterization reveals that the Pt/3D-G catalyst has a more negative onset potential as well as a higher electrochemically active specific surface area than a commercial Pt/C catalyst. Moreover, the catalyst exhibits higher tolerance to corrosion than carbon black. This work provides an efficient way for preparing 3D-G as a promising support for the oxidation of small organic molecules in fuel cells.

  20. GIS-based 3D limit equilibrium analysis for design optimization of a 600 m high slope in an open pit mine

    Institute of Scientific and Technical Information of China (English)

    Meifeng Cai; Mowen Xie; Chunlei Li

    2007-01-01

    Combining the GIS (geographic information systems) grid-based data with four proposed column-based 3D slope stability analysis models,a comprehensive solution of a high-steep open-pit slope has been obtained.For six searching ranges,19 critical slip surfaces of different sizes have been studied,in which the minimum 3D safety factor is 1.33.Comparison of 3D safety factors of designed and proposed slope plans shows for all the critical slip surfaces for the proposed plan,the smallest 3D safety factor is 1.33 under the most unfavorable condition.This means that the proposed plan of the high slopes,about 600 m,of an open pit (2-5°steeper than designed plan) is feasible.

  1. EUROPEANA AND 3D

    Directory of Open Access Journals (Sweden)

    D. Pletinckx

    2012-09-01

    Full Text Available The current 3D hype creates a lot of interest in 3D. People go to 3D movies, but are we ready to use 3D in our homes, in our offices, in our communication? Are we ready to deliver real 3D to a general public and use interactive 3D in a meaningful way to enjoy, learn, communicate? The CARARE project is realising this for the moment in the domain of monuments and archaeology, so that real 3D of archaeological sites and European monuments will be available to the general public by 2012. There are several aspects to this endeavour. First of all is the technical aspect of flawlessly delivering 3D content over all platforms and operating systems, without installing software. We have currently a working solution in PDF, but HTML5 will probably be the future. Secondly, there is still little knowledge on how to create 3D learning objects, 3D tourist information or 3D scholarly communication. We are still in a prototype phase when it comes to integrate 3D objects in physical or virtual museums. Nevertheless, Europeana has a tremendous potential as a multi-facetted virtual museum. Finally, 3D has a large potential to act as a hub of information, linking to related 2D imagery, texts, video, sound. We describe how to create such rich, explorable 3D objects that can be used intuitively by the generic Europeana user and what metadata is needed to support the semantic linking.

  2. High-resolution sub-bottom sonar imaging and 3D modeling of drowned Pleistocene river paleochannel architecture (Strunjan bay, Adriatic Sea)

    Science.gov (United States)

    Trobec, Ana; Šmuc, Andrej; Poglajen, Sašo; Vrabec, Marko

    2015-04-01

    In the Gulf of Trieste (northern Adriatic), the seafloor is covered by up to several 100s of m of continental sediments, characterized predominately by alluvial and aeolian deposits that formed during Pleistocene sea-level lowstands. High-resolution multibeam bathymetry revealed the existence of several meandering river channels. One such channel appears to be vertically offset across a linear, NE-SW striking morphological flexure, which could be an expression of active faulting. Initial sub-bottom sonar profiles showed abrupt terminations of subhorizontal strata of Pleistocene sediments which roughly coincide with the flexure position. To obtain a high-resolution 3D interpretation of this peculiar feature, we investigated the outermost part of the Strunjan bay (southern Slovenian coast). A grid of 25 m spaced sub-bottom profiles covering the area of 1225 x 500 m and comprising a total of 71 orthogonal profiles was acquired with the Innomar parametric sediment echo sounder SES-2000, using a sampling interval of 69 μs and a frequency of 8000 Hz. Data processing included conversion from proprietary to standard SEG-Y data format, deconvolution, elimination of swell movement and Automatic Gain Control. Geopositioned profiles were interpreted and correlated in IHS Kingdom seismic interpretation software, which was used to pick horizons and model 3D geometry of key stratigraphic surfaces. Four distinct acoustic facies were resolved from the sonar profiles to a depth of up to 10 m below the seafloor. The first reflection represents the seafloor, ranging in depth from 20 to 26 m. Acoustic facies A in the immediate subsurface represents Holocene marine sediments that are up to 9 m thick. The paleochannel and associated river deposits are represented in the underlying acoustic facies B. Characteristic for this facies is strong attenuation of signal along the river channel which we interpret as a consequence of lateral channel migration and/or later gas accumulations in this

  3. Solid works 3D

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Cheol Yeong

    2004-02-15

    This book explains modeling of solid works 3D and application of 3D CAD/CAM. The contents of this book are outline of modeling such as CAD and 2D and 3D, solid works composition, method of sketch, writing measurement fixing, selecting projection, choosing condition of restriction, practice of sketch, making parts, reforming parts, modeling 3D, revising 3D modeling, using pattern function, modeling necessaries, assembling, floor plan, 3D modeling method, practice floor plans for industrial engineer data aided manufacturing, processing of CAD/CAM interface.

  4. Solid works 3D

    International Nuclear Information System (INIS)

    This book explains modeling of solid works 3D and application of 3D CAD/CAM. The contents of this book are outline of modeling such as CAD and 2D and 3D, solid works composition, method of sketch, writing measurement fixing, selecting projection, choosing condition of restriction, practice of sketch, making parts, reforming parts, modeling 3D, revising 3D modeling, using pattern function, modeling necessaries, assembling, floor plan, 3D modeling method, practice floor plans for industrial engineer data aided manufacturing, processing of CAD/CAM interface.

  5. High-resolution 3-D imaging of surface damage sites in fused silica with Optical Coherence Tomography

    Energy Technology Data Exchange (ETDEWEB)

    Guss, G; Bass, I; Hackel, R; Mailhiot, C; Demos, S G

    2007-10-30

    In this work, we present the first successful demonstration of a non-contact technique to precisely measure the 3D spatial characteristics of laser induced surface damage sites in fused silica for large aperture laser systems by employing Optical Coherence Tomography (OCT). What makes OCT particularly interesting in the characterization of optical materials for large aperture laser systems is that its axial resolution can be maintained with working distances greater than 5 cm, whether viewing through air or through the bulk of thick optics. Specifically, when mitigating surface damage sites against further growth by CO{sub 2} laser evaporation of the damage, it is important to know the depth of subsurface cracks below the damage site. These cracks are typically obscured by the damage rubble when imaged from above the surface. The results to date clearly demonstrate that OCT is a unique and valuable tool for characterizing damage sites before and after the mitigation process. We also demonstrated its utility as an in-situ diagnostic to guide and optimize our process when mitigating surface damage sites on large, high-value optics.

  6. Study on Bubbly Two-Phase Flow Across Twisted Tube Bundles Based on Quasi 3D High Speed Video

    Directory of Open Access Journals (Sweden)

    Jicheng Zhou

    2013-12-01

    Full Text Available In flooded evaporators, refrigerants are boiling outside the tubes. This paper focuses on the bubbly two-phase flow characteristics in twisted tube bundles. The quasi 3-D high speed video method and computational fluid dynamics are carried out to understand the effects which angles between the major axis of the cylinder and vertical direction ( and bubble diameters have on the motion behaviours of bubbly flow.  is adjusted to 0°, 30°, 45° and 60°,respectively. Bubble diameter is 4mm, 6mm and 8mm, respectively. The turbulence intensity of fluid outside the tubes which is resulted by bubble rising behaviour is also investigated. The results show that the elliptical cylinders with different  s lead to bubble sliding out the surface of tubes, rising steadily and spreading widely in tube bundles. And larger bubbles have a stronger effect on turbulence intensity of liquid phase flow. It also can be concluded that the surface geometry of twisted tube plays an active role in heat transfer enhancement of the twisted tube evaporator

  7. Characterization of 3D Trench PZT Capacitors for High Density FRAM Devices by Synchrotron X-ray Micro-diffraction

    Science.gov (United States)

    Shin, Sangmin; Han, Hee; Park, Yong Jun; Choi, Jae-Young; Park, Youngsoo; Baik, Sunggi

    2007-01-01

    3D trench PbZrxTi1-xO3 (PZT) capacitors for 256 Mbit 1T-1C FRAM devices were characterized by synchrotron X-ray micro-diffraction at Pohang Light Source. Three layes, Ir/PZT/Ir were deposited on SiO2 trench holes with different widths ranging from 180 nm to 810 nm and 400 nm in depth by ALD and MOCVD. Each hole is separated from neighboring holes by 200 nm. The cross sectional TEM analysis for the trenches revealed that the PZT layers were consisted of columnar grains at the trench entrance and changes to polycrystalline granular grains at the lower part of the trench. The transition from columnar to granular grains was dependent on the trench size. The smaller trenches were favorable to granular grain formation. High resolution synchrotron X-ray diffraction analysis was performed to determine the crystal structure of each region. The beam was focused to about 500 μm and the diffraction patterns were obtained from a single trench. Only the peaks corresponding to ferroelectric tetragonal phases are observed for the trenches larger than 670 nm, which consist of fully columnar grains. However, the trenches smaller than 670 nm showed the peaks corresponding the pyrochlore phases, which suggested that the granular grains are of pyrochlore phases and non-ferroelectric.

  8. Structural modelling and testing of failed high energy pipe runs: 2D and 3D pipe whip

    Energy Technology Data Exchange (ETDEWEB)

    Reid, S.R., E-mail: steve.reid@abdn.ac.uk [School of Engineering, University of Aberdeen, Aberdeen AB24 3UE (United Kingdom); Wang, B.; Aleyaasin, M. [School of Engineering, University of Aberdeen, Aberdeen AB24 3UE (United Kingdom)

    2011-05-15

    The sudden rupture of a high energy piping system is a safety-related issue and has been the subject of extensive study and discussed in several industrial reports (e.g. ). The dynamic plastic response of the deforming pipe segment under the blow-down force of the escaping liquid is termed pipe whip. Because of the potential damage that such an event could cause, various geometric and kinematic features of this phenomenon have been modelled from the point of view of dynamic structural plasticity. After a comprehensive summary of the behaviour of in-plane deformation of pipe runs that deform in 2D in a plane, the more complicated case of 3D out-of-plane deformation is discussed. Both experimental studies and modelling using analytical and FE methods have been carried out and they show that, for a good estimate of the 'hazard zone' when unconstrained pipe whip motion could occur, a large displacement analysis is essential. The classical, rigid plastic, small deflection analysis (e.g. see ), is valid for estimating the initial failure mechanisms, however it is insufficient for describing the details and consequences of large deflection behaviour. - Highlights: > Dynamic plastic response of piping system under extreme loading (fluid escape). > Two and three dimensional analysis of the pipe whipping phenomena. > Comparison between theory and the experiments. > Determination of the Hazard Zone (HZ) and safety-related issues.

  9. High-performance parallel solver for 3D time-dependent Schrodinger equation for large-scale nanosystems

    Science.gov (United States)

    Gainullin, I. K.; Sonkin, M. A.

    2015-03-01

    A parallelized three-dimensional (3D) time-dependent Schrodinger equation (TDSE) solver for one-electron systems is presented in this paper. The TDSE Solver is based on the finite-difference method (FDM) in Cartesian coordinates and uses a simple and explicit leap-frog numerical scheme. The simplicity of the numerical method provides very efficient parallelization and high performance of calculations using Graphics Processing Units (GPUs). For example, calculation of 106 time-steps on the 1000ṡ1000ṡ1000 numerical grid (109 points) takes only 16 hours on 16 Tesla M2090 GPUs. The TDSE Solver demonstrates scalability (parallel efficiency) close to 100% with some limitations on the problem size. The TDSE Solver is validated by calculation of energy eigenstates of the hydrogen atom (13.55 eV) and affinity level of H- ion (0.75 eV). The comparison with other TDSE solvers shows that a GPU-based TDSE Solver is 3 times faster for the problems of the same size and with the same cost of computational resources. The usage of a non-regular Cartesian grid or problem-specific non-Cartesian coordinates increases this benefit up to 10 times. The TDSE Solver was applied to the calculation of the resonant charge transfer (RCT) in nanosystems, including several related physical problems, such as electron capture during H+-H0 collision and electron tunneling between H- ion and thin metallic island film.

  10. HIGH RESOLUTION X-RAY TECHNIQUES AS NEW TOOL TO INVESTIGATE THE 3D VASCULARIZATION OF ENGINEERED-BONE TISSUE

    Directory of Open Access Journals (Sweden)

    Inna eBukreeva

    2015-09-01

    Full Text Available The understanding of structure-function relationships in normal and pathologic mammalian tissues is at the basis of tissue engineering (TE approach for the development of biological substitutes to restore or improve tissue function. In this framework it is interesting to investigate engineered bone tissue, which is formed when porous ceramic constructs are loaded with Bone Marrow Stromal Cells (BMSC and implanted in vivo. To monitor the relation between bone formation and vascularization, it is important to achieve a detailed imaging and a quantitative description of the complete three-dimensional vascular network in such constructs. Here we used synchrotron X-ray phase contrast micro-tomography to visualize and analyze the three-dimensional micro-vascular networks in bone-engineered constructs, in ectopic bone formation mouse-model. We compared samples seeded with and without BMSC as well as samples differently stained (comprising unstained samples. Thanks to the high quality of the images, we investigated the 3D distribution of both vessels and collagen matrix and we obtained quantitative information for all different sample preparations.We propose our approach as a tool for quantitative studies of angiogenesis in TE and for any other pre-clinical investigations where a quantitative analysis of the vascular network is required.

  11. Highly optimized simulations on single- and multi-GPU systems of the 3D Ising spin glass model

    Science.gov (United States)

    Lulli, M.; Bernaschi, M.; Parisi, G.

    2015-11-01

    We present a highly optimized implementation of a Monte Carlo (MC) simulator for the three-dimensional Ising spin-glass model with bimodal disorder, i.e., the 3D Edwards-Anderson model running on CUDA enabled GPUs. Multi-GPU systems exchange data by means of the Message Passing Interface (MPI). The chosen MC dynamics is the classic Metropolis one, which is purely dissipative, since the aim was the study of the critical off-equilibrium relaxation of the system. We focused on the following issues: (i) the implementation of efficient memory access patterns for nearest neighbours in a cubic stencil and for lagged-Fibonacci-like pseudo-Random Numbers Generators (PRNGs); (ii) a novel implementation of the asynchronous multispin-coding Metropolis MC step allowing to store one spin per bit and (iii) a multi-GPU version based on a combination of MPI and CUDA streams. Cubic stencils and PRNGs are two subjects of very general interest because of their widespread use in many simulation codes.

  12. Self-arrangement of nanoparticles toward crystalline metal oxides with high surface areas and tunable 3D mesopores

    Science.gov (United States)

    Lee, Hyung Ik; Lee, Yoon Yun; Kang, Dong-Uk; Lee, Kirim; Kwon, Young-Uk; Kim, Ji Man

    2016-02-01

    We demonstrate a new design concept where the interaction between silica nanoparticles (about 1.5 nm in diameter) with titania nanoparticles (anatase, about 4 nm or 6 nm in diameter) guides a successful formation of mesoporous titania with crystalline walls and controllable porosity. At an appropriate solution pH (~1.5, depending on the deprotonation tendencies of two types of nanoparticles), the smaller silica nanoparticles, which attach to the surface of the larger titania nanoparticles and provide a portion of inactive surface and reactive surface of titania nanoparticles, dictate the direction and the degree of condensation of the titania nanoparticles, resulting in a porous 3D framework. Further crystallization by a hydrothermal treatment and subsequent removal of silica nanoparticles result in a mesoporous titania with highly crystalline walls and tunable mesopore sizes. A simple control of the Si/Ti ratio verified the versatility of the present method through the successful control of mean pore diameter in the range of 2-35 nm and specific surface area in the ranges of 180-250 m2 g-1. The present synthesis method is successfully extended to other metal oxides, their mixed oxides and analogues with different particle sizes, regarding as a general method for mesoporous metal (or mixed metal) oxides.

  13. An Acinetobacter trimeric autotransporter adhesin reaped from cells exhibits its nonspecific stickiness via a highly stable 3D structure.

    Science.gov (United States)

    Yoshimoto, Shogo; Nakatani, Hajime; Iwasaki, Keita; Hori, Katsutoshi

    2016-01-01

    Trimeric autotransporter adhesins (TAAs), cell surface proteins of Gram-negative bacteria, mediate bacterial adhesion to host cells and extracellular matrix proteins. However, AtaA, a TAA in the nonpathogenic Acinetobacter sp. strain Tol 5, shows nonspecific, high adhesiveness to abiotic material surfaces as well as to biotic surfaces. AtaA is a homotrimer of polypeptides comprising 3,630 amino acids and forms long nanofibers; therefore, it is too large and structurally complex to be produced as a recombinant protein. In this study, we isolated AtaA's passenger domain (AtaA PSD), which is translocated to the cell surface through the C-terminal transmembrane domain and exhibits biological functions, using a new method. We introduced a protease recognition site and reaped AtaA nanofibers 225 nm in length from the cell surface through proteolytic cleavage with a specific protease. Biochemical and biophysical analyses of the purified native AtaA PSD revealed that it has a stable structure under alkaline and acidic conditions. Temperatures above 80 °C, which disrupted AtaA's higher-order structure but maintained the full-length AtaA polypeptide, inactivated AtaA's nonspecific adhesiveness, suggesting that the stickiness of AtaA requires its 3D structure. This finding refutes the widespread but vague speculation that large unfolded polypeptides readily stick to various surfaces. PMID:27305955

  14. Highly uniform residual layers for arrays of 3D nanoimprinted cavities in Fabry-Pérot-filter-array-based nanospectrometers

    Science.gov (United States)

    Memon, Imran; Shen, Yannan; Khan, Abdullah; Woidt, Carsten; Hillmer, Hartmut

    2016-04-01

    Miniaturized optical spectrometers can be implemented by an array of Fabry-Pérot (FP) filters. FP filters are composed of two highly reflecting parallel mirrors and a resonance cavity. Each filter transmits a small spectral band (filter line) depending on its individual cavity height. The optical nanospectrometer, a miniaturized FP-based spectrometer, implements 3D NanoImprint technology for the fabrication of multiple FP filter cavities in a single process step. However, it is challenging to avoid the dependency of residual layer (RL) thickness on the shape of the printed patterns in NanoImprint. Since in a nanospectrometer the filter cavities vary in height between neighboring FP filters and, thus, the volume of each cavity varies causing that the RL varies slightly or noticeably between different filters. This is one of the few disadvantages of NanoImprint using soft templates such as substrate conformal imprint lithography which is used in this paper. The advantages of large area soft templates can be revealed substantially if the problem of laterally inhomogeneous RLs can be avoided or reduced considerably. In the case of the nanospectrometer, non-uniform RLs lead to random variations in the designed cavity heights resulting in the shift of desired filter lines. To achieve highly uniform RLs, we report a volume-equalized template design with the lateral distribution of 64 different cavity heights into several units with each unit comprising four cavity heights. The average volume of each unit is kept constant to obtain uniform filling of imprint material per unit area. The imprint results, based on the volume-equalized template, demonstrate highly uniform RLs of 110 nm thickness.

  15. Plant tissues in 3D via X-ray tomography: simple contrasting methods allow high resolution imaging.

    Directory of Open Access Journals (Sweden)

    Yannick M Staedler

    Full Text Available Computed tomography remains strongly underused in plant sciences despite its high potential in delivering detailed 3D phenotypical information because of the low X-ray absorption of most plant tissues. Existing protocols to study soft tissues display poor performance, especially when compared to those used on animals. More efficient protocols to study plant material are therefore needed. Flowers of Arabidopsis thaliana and Marcgravia caudata were immersed in a selection of contrasting agents used to treat samples for transmission electron microscopy. Grayscale values for floral tissues and background were measured as a function of time. Contrast was quantified via a contrast index. The thick buds of Marcgravia were scanned to determine which contrasting agents best penetrate thick tissues. The highest contrast increase with cytoplasm-rich tissues was obtained with phosphotungstate, whereas osmium tetroxide and bismuth tatrate displayed the highest contrast increase with vacuolated tissues. Phosphotungstate also displayed the best sample penetration. Furthermore, infiltration with phosphotungstate allowed imaging of all plants parts at a high resolution of 3 µm, which approaches the maximum resolution of our equipment: 1.5 µm. The high affinity of phosphotungstate for vasculature, cytoplasm-rich tissue, and pollen causes these tissues to absorb more X-rays than the surrounding tissues, which, in turn, makes these tissues appear brighter on the scan data. Tissues with different brightness can then be virtually dissected from each other by selecting the bracket of grayscale to be visualized. Promising directions for the future include in silico phenotyping and developmental studies of plant inner parts (e.g., ovules, vasculature, pollen, and cell nuclei via virtual dissection as well as correlations of quantitative phenotypes with omics datasets. Therefore, this work represents a crucial improvement of previous methods, allowing new directions of

  16. Construction of 3D polymer brushes by dip-pen nanodisplacement lithography: understanding the molecular displacement for ultrafine and high-speed patterning.

    Science.gov (United States)

    Chen, Chaojian; Zhou, Xuechang; Xie, Zhuang; Gao, Tingting; Zheng, Zijian

    2015-02-01

    Dip-pen nanodisplacement lithography (DNL) is a versatile scanning probe-based technique that can be employed for fabricating ultrafine 3D polymer brushes under ambient conditions. Many fundamental studies and applications require the large-area fabrication of 3D structures. However, the fabrication throughput and uniformity are still far from satisfactory. In this work, the molecular displacement mechanism of DNL is elucidated by systematically investigating the synergistic effect of z extension and contact time. The in-depth understanding of molecular displacement results in the successful achievement of ultrafine control of 3D structures and high-speed patterning at the same time. Remarkably, one can prepare arbitrary 3D polymer brushes on a large area (1.3 mm × 1.3 mm), with <5% vertical and lateral size variations, and a patterning speed as much as 200-fold faster than the current state-of-the-art. PMID:25256006

  17. Polyaniline/Carbon Nitride Nanosheets Composite Hydrogel: A Separation-Free and High-Efficient Photocatalyst with 3D Hierarchical Structure.

    Science.gov (United States)

    Jiang, Wenjun; Luo, Wenjiao; Zong, Ruilong; Yao, Wenqing; Li, Zhanping; Zhu, Yongfa

    2016-08-01

    A polyaniline (PANI)/carbon nitride nanosheets (CNNS) composite hydrogel with 3D hierarchical nanostructure is synthesized via in situ polymerization. The 3D hierarchical structure is robust and stable, making the composite hydrogel separation-free and easy to recycling. It is highly excellent in removing organic pollutant for PANI/CNNS composite hydrogel on account of the cooperation of adsorptive preconcentration and the following photocatalytic oxidation. Pollutants are first adsorbed and concentrated into the 3D hierarchical nanostructure of the composite hydrogel. Then the pollutants are in situ oxidized via photocatalysis. The promoted photocatalytic performance can be mainly ascribed to the outstanding interfacial charge separation and photoelectrochemical performance. A new idea of the construction of 3D hierarchical photocatalysts is presented, which can be applied in the sustainability field.

  18. Development of a 3D Tissue Culture-Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine Kinases.

    Science.gov (United States)

    Booij, Tijmen H; Klop, Maarten J D; Yan, Kuan; Szántai-Kis, Csaba; Szokol, Balint; Orfi, Laszlo; van de Water, Bob; Keri, Gyorgy; Price, Leo S

    2016-10-01

    3D tissue cultures provide a more physiologically relevant context for the screening of compounds, compared with 2D cell cultures. Cells cultured in 3D hydrogels also show complex phenotypes, increasing the scope for phenotypic profiling. Here we describe a high-content screening platform that uses invasive human prostate cancer cells cultured in 3D in standard 384-well assay plates to study the activity of potential therapeutic small molecules and antibody biologics. Image analysis tools were developed to process 3D image data to measure over 800 phenotypic parameters. Multiparametric analysis was used to evaluate the effect of compounds on tissue morphology. We applied this screening platform to measure the activity and selectivity of inhibitors of the c-Met and epidermal growth factor (EGF) receptor (EGFR) tyrosine kinases in 3D cultured prostate carcinoma cells. c-Met and EGFR activity was quantified based on the phenotypic profiles induced by their respective ligands, hepatocyte growth factor and EGF. The screening method was applied to a novel collection of 80 putative inhibitors of c-Met and EGFR. Compounds were identified that induced phenotypic profiles indicative of selective inhibition of c-Met, EGFR, or bispecific inhibition of both targets. In conclusion, we describe a fully scalable high-content screening platform that uses phenotypic profiling to discriminate selective and nonselective (off-target) inhibitors in a physiologically relevant 3D cell culture setting.

  19. A new type of 3-D peripheral ultrastructure in Glaucocystis (Glaucocystales, Glaucophyta) as revealed by ultra-high voltage electron microscopy.

    Science.gov (United States)

    Takahashi, Toshiyuki; Nishida, Tomoki; Saito, Chieko; Yasuda, Hidehiro; Nozaki, Hisayoshi

    2016-06-01

    The coccoid glaucophyte genus Glaucocystis is characterized by having a thick cell wall, which has to date prohibited examination of the native ultrastructural features of the protoplast periphery. Recently, however, the three-dimensional (3-D) ultrastructure of the protoplast periphery was revealed in two divergent Glaucocystis species, with the world's most powerful ultra-high voltage electron microscope (UHVEM). The two species exhibit morphological diversity in terms of their 3-D ultrastructural features. However, these two types do not seem to encompass actual ultrastructural diversity in the genetically diverse genus Glaucocystis. Here, we report a new type of peripheral 3-D ultrastructure resolved in "G. incrassata" SAG 229-2 cells by 3-D modeling based on UHVEM tomography using high-pressure freezing and freeze-substitution fixation. The plasma membrane and underlying flattened vesicles in "G. incrassata" SAG 229-2 exhibited grooves at intervals of 200-600 nm, and the flattened vesicles often overlapped one another at the protoplast periphery. This 3-D ultrastructure differs from those of the two types previously reported in other species of Glaucocystis. The possibility of classification of Glaucocystis species based on the 3-D ultrastructure of the protoplast periphery is discussed. PMID:27273537

  20. High 3D:5D ratio: A possible correlate of externalizing and internalizing problems: An exploratory study

    Directory of Open Access Journals (Sweden)

    Esther I. de Bruin

    2011-03-01

    Full Text Available Background and Objectives: The second to fourth (2D:4D digit ratio is a sexually dimorphic trait which has been studied to examine the association between fetal hormones and a variety of behaviors. Lower 2D:4D ratios, suggestive of exposure to higher levels of prenatal testosterone, have been associated with male-linked disorders, while higher 2D:4D ratios, suggestive of exposure to weaker prenatal androgen action, have been associated with female-linked disorders. Past research has concentrated on the 2D:4D ratio, whereas the relationship between other ratios, such as the 3D:5D ratio, and psychopathology has not much been studied before. Therefore, the aim of this study was to assess the correlation between the 2D:4D and 3D:5D ratio, and internalizing as well as externalizing symptoms, in a large non-clinical sample (143 boys, 150 girls of white Caucasian children aged 7 to 13 years. Methods: Externalizing and internalizing symptoms were assessed with the Child Behavior Checklist (CBCL. Results: The 3D:5D ratio in boys and in girls was positively associated with scores on Externalizing Problems. Further, in girls only, the 3D:5D ratio was positively correlated to scores on Internalizing Problems. Conclusions: The 3D:5D ratio can be considered a correlate of externalizing and internalizing problems in children from the general population.

  1. 3D Printing of Graphene Aerogels.

    Science.gov (United States)

    Zhang, Qiangqiang; Zhang, Feng; Medarametla, Sai Pradeep; Li, Hui; Zhou, Chi; Lin, Dong

    2016-04-01

    3D printing of a graphene aerogel with true 3D overhang structures is highlighted. The aerogel is fabricated by combining drop-on-demand 3D printing and freeze casting. The water-based GO ink is ejected and freeze-cast into designed 3D structures. The lightweight (aerogel presents superelastic and high electrical conduction. PMID:26861680

  2. Reconstruct the high myopic eye modules with 3D-MRI imaging technology%应用3D-MRI成像技术重建高度近视眼球形态

    Institute of Scientific and Technical Information of China (English)

    施靖容; 何玉萍; 赵婷婷; 陈秋莹; 华怡红; 胡运胜; 李念云; 张琳; 张贵祥

    2016-01-01

    目的 利用3D-MRI眼球建模技术探讨高度近视眼的MRI影像表现、形态特征,并与其他影像方法比较,评估其临床价值.方法 横断面研究.65例(124眼)高度近视患者(球镜度高于-6.00 D,且眼轴长度≥26 mm)进行眼部常规临床检查、眼眶磁共振检查,其中40例(80眼)进行眼部B超检查.磁共振图像经处理为眼球模型.按年龄分为<50岁组和≥50岁组.按球镜度分为:①-6.00~-12.00 D组,②-12.25~-18.00 D组,③-18.25~-24.00 D组.按眼轴分为:①26.00~28.00 mm组,②28.01~30.00 mm组,③30.01~32.00 mm组,④>32.00 mm组.MRI与B超对于后巩膜葡萄肿的诊断准确率比较采用McNemar检验,不同组别中眼球类型的分布差异采用卡方检验.结果 B超检出后巩膜葡萄肿的诊断准确率为70%,MRI检出后巩膜葡萄肿的诊断准确率为100%,差异有统计学意义(P<0.05).高度近视眼球形态可分为球型、锥型、碗型、柱型4种类型,碗型、锥型视为后巩膜葡萄肿存在.而4种眼球类型的分布在不同年龄组(x2=57.19,P<0.05)、不同眼轴组(x2=87.36,P<0.05)中的差异有统计学意义,在不同球镜度组(x2=67.94,P>0.05)中的差异没有统计学意义.部分病例于MRI眼球模型上可见不规则隆起与凹陷,但B超不能精确显示.结论 3D-MRI眼球建模能清晰显示高度近视眼球形态与后巩膜葡萄肿的位置及特征,在眼科影像检查手段中诊断准确率高于B超检查,可作为高度近视眼科检查的新手段.%Objective Analyze the shapes and features of high myopic eyes by 3D-MRI exanmination.To investigate 3D-MRI exanmination methods and imaging manifestations of high myopic eyes,and to evaluate its clinical values when comparing with other diagnostic imaging facilities.Methods 65 cases (124 eyes) of high myopic (the spherical diopter was equal or less than-6.00 diopter,and the eye axial length was equal or more than 26 mm) accepted the routine

  3. Detection of latent fingerprints using high-resolution 3D confocal microscopy in non-planar acquisition scenarios

    Science.gov (United States)

    Kirst, Stefan; Vielhauer, Claus

    2015-03-01

    In digitized forensics the support of investigators in any manner is one of the main goals. Using conservative lifting methods, the detection of traces is done manually. For non-destructive contactless methods, the necessity for detecting traces is obvious for further biometric analysis. High resolutional 3D confocal laser scanning microscopy (CLSM) grants the possibility for a detection by segmentation approach with improved detection results. Optimal scan results with CLSM are achieved on surfaces orthogonal to the sensor, which is not always possible due to environmental circumstances or the surface's shape. This introduces additional noise, outliers and a lack of contrast, making a detection of traces even harder. Prior work showed the possibility of determining angle-independent classification models for the detection of latent fingerprints (LFP). Enhancing this approach, we introduce a larger feature space containing a variety of statistical-, roughness-, color-, edge-directivity-, histogram-, Gabor-, gradient- and Tamura features based on raw data and gray-level co-occurrence matrices (GLCM) using high resolutional data. Our test set consists of eight different surfaces for the detection of LFP in four different acquisition angles with a total of 1920 single scans. For each surface and angles in steps of 10, we capture samples from five donors to introduce variance by a variety of sweat compositions and application influences such as pressure or differences in ridge thickness. By analyzing the present test set with our approach, we intend to determine angle- and substrate-dependent classification models to determine optimal surface specific acquisition setups and also classification models for a general detection purpose for both, angles and substrates. The results on overall models with classification rates up to 75.15% (kappa 0.50) already show a positive tendency regarding the usability of the proposed methods for LFP detection on varying surfaces in non

  4. 3D MODELING OF GJ1214b's ATMOSPHERE: FORMATION OF INHOMOGENEOUS HIGH CLOUDS AND OBSERVATIONAL IMPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Charnay, B.; Meadows, V.; Misra, A.; Arney, G. [Astronomy Department, University of Washington, Seattle, WA 98125 (United States); Leconte, J., E-mail: bcharnay@uw.edu [Canadian Institute for Theoretical Astrophysics, 60 St George Street, University of Toronto, Toronto, ON M5S 3H8 (Canada)

    2015-11-01

    The warm sub-Neptune GJ1214b has a featureless transit spectrum that may be due to the presence of high and thick clouds or haze. Here, we simulate the atmosphere of GJ1214b with a 3D General Circulation Model for cloudy hydrogen-dominated atmospheres, including cloud radiative effects. We show that the atmospheric circulation is strong enough to transport micrometric cloud particles to the upper atmosphere and generally leads to a minimum of cloud at the equator. By scattering stellar light, clouds increase the planetary albedo to 0.4–0.6 and cool the atmosphere below 1 mbar. However, the heating by ZnS clouds leads to the formation of a stratospheric thermal inversion above 10 mbar, with temperatures potentially high enough on the dayside to evaporate KCl clouds. We show that flat transit spectra consistent with Hubble Space Telescope observations are possible if cloud particle radii are around 0.5 μm, and that such clouds should be optically thin at wavelengths >3 μm. Using simulated cloudy atmospheres that fit the observed spectra we generate transit, emission, and reflection spectra and phase curves for GJ1214b. We show that a stratospheric thermal inversion would be readily accessible in near- and mid-infrared atmospheric spectral windows. We find that the amplitude of the thermal phase curves is strongly dependent on metallicity, but only slightly impacted by clouds. Our results suggest that primary and secondary eclipses and phase curves observed by the James Webb Space Telescope in the near- to mid-infrared should provide strong constraints on the nature of GJ1214b's atmosphere and clouds.

  5. Highly Resolved Long-term 3D Hydrological Simulation of a Forested Catchment with Litter Layer and Fractured Bedrock

    Science.gov (United States)

    Fang, Z.; Bogena, H. R.; Kollet, S. J.; Vereecken, H.

    2014-12-01

    Soil water content plays a key role in the water and energy balance in soil, vegetation and atmosphere systems. According to Wood et al. (2011) there is a grand need to increase global-scale hyper-resolution water-energy-biogeochemistry land surface modelling capabilities. However, such a model scheme should also recognize the epistemic uncertainties, as well as the nonlinearity and hysteresis in its dynamics. Unfortunately, it is not clear how to parameterize hydrological processes as a function of scale and how to test deterministic models with regard to epistemic uncertainties. In this study, high resolution long-term simulations were conducted in the highly instrumented TERENO hydrological observatory, the Wüstebach catchment. Soil hydraulic parameters were derived using inverse modeling with the Hydrus-1D model using the global optimization scheme SCE-UA and soil moisture data from a wireless soil moisture sensor network. The estimated parameters were then used for 3D simulations using the integrated parallel simulation platform ParFlow-CLM. The simulated soil water content, as well as evapotranspiration and runoff, were compared with long-term field observations to illustrate how well the model was able to reproduce the water budget dynamics. With variable model setup scenarios in boundary conditions and anisotropy of hydraulic conductivity, we investigated how lateral flow processes above the underlying fractured bedrock affects the simulation results. Furthermore, we explored the importance of the litter layer and the heterogeneity of the forest soil in the simulation of flow processes and model performance. For the analysis of spatial patterns of simulated and observed soil water content we applied the method of empirical orthogonal function (EOF). The results suggest that strong anisotropy in the hydraulic conductivity may be the reason for the fast lateral flow observed in Wüstebach. Introduction of heterogeneity in the hydraulic properties in the

  6. An efficient compact fourth order FD method for simulating 3-D mantle convection at high Rayleigh number

    Science.gov (United States)

    Wright, G. B.; Barnett, G. A.; Yuen, D. A.

    2009-12-01

    , 533, 1984. Isosurfaces of the temperature field from a 3-D mantle convection simulation at Rayleigh number 10**7 during the transition from a purely conductive state to a double-layer convection state. Simulation was performed using the compact fourth order finite difference scheme at a resolution of 200-by-200-by-100 (length-by-width-by-height).

  7. High frequency, high power capacitor development

    Science.gov (United States)

    White, C. W.; Hoffman, P. S.

    1983-03-01

    A program to develop a special high energy density, high power transfer capacitor to operate at frequency of 40 kHz, 600 V rms at 125 A rms plus 600 V dc bias for space operation. The program included material evaluation and selection, a capacitor design was prepared, a thermal analysis performed on the design. Fifty capacitors were manufactured for testing at 10 kHz and 40 kHz for 50 hours at Industrial Electric Heating Co. of Columbus, Ohio. The vacuum endurance test used on environmental chamber and temperature plate furnished by Maxwell. The capacitors were energized with a special power conditioning apparatus developed by Industrial Electric Heating Co. Temperature conditions of the capacitors were monitored by IEHCo test equipment. Successful completion of the vacuum endurance test series confirmed achievement of the main goal of producing a capacitor or reliable operation at high frequency in an environment normally not hospitable to electrical and electronic components. The capacitor developed compared to a typical commercial capacitor at the 40 kHz level represents a decrease in size and weight by a factor of seven.

  8. High Frequency Characteristic Of Rogowski Coil

    Directory of Open Access Journals (Sweden)

    Ping Li

    2012-12-01

    Full Text Available According to the transfer impedance getting from distributed parameter model,we analyse the influences of magnetic conductivity ,the number of turns ,capacitance to the shield and interturn capacitance on the high frequency characteristic of Rogowski coil through theories and simulations. Simulation shows that there are a series of zeros in high frequency band, but on the whole, the high frequency response does not change with the increase of frequency. The magnetic conductivity, number of turns and capacitance to the shield can influence the frequency at which zero appears, but the high frequency characteristic of Rogowski coil can’t be influenced. Considering the interturn capacitance, the curve of high-frequency response characteristic presents a "V" shape ", and this leads to the reduction of higher cut-off frequency. So we should try to decrease the interturn capacitance to reduce the influence on the high frequency characteristic.

  9. Econometrics of financial high-frequency data

    CERN Document Server

    Hautsch, Nikolaus

    2011-01-01

    This book covers major approaches in high-frequency econometrics. It discusses implementation details, provides insights into properties of high-frequency data as well as institutional settings and presents applications.

  10. 3d-3d correspondence revisited

    Science.gov (United States)

    Chung, Hee-Joong; Dimofte, Tudor; Gukov, Sergei; Sułkowski, Piotr

    2016-04-01

    In fivebrane compactifications on 3-manifolds, we point out the importance of all flat connections in the proper definition of the effective 3d {N}=2 theory. The Lagrangians of some theories with the desired properties can be constructed with the help of homological knot invariants that categorify colored Jones polynomials. Higgsing the full 3d theories constructed this way recovers theories found previously by Dimofte-Gaiotto-Gukov. We also consider the cutting and gluing of 3-manifolds along smooth boundaries and the role played by all flat connections in this operation.

  11. Beyond optical molasses: 3D raman sideband cooling of atomic cesium to high phase-space density

    Science.gov (United States)

    Kerman; Vuletic; Chin; Chu

    2000-01-17

    We demonstrate a simple, general purpose method to cool neutral atoms. A sample containing 3x10(8) cesium atoms prepared in a magneto-optical trap is cooled and simultaneously spin polarized in 10 ms at a density of 1.1x10(11) cm (-3) to a phase space density nlambda(3)(dB) = 1/500, which is almost 3 orders of magnitude higher than attainable in free space with optical molasses. The technique is based on 3D degenerate Raman sideband cooling in optical lattices and remains efficient even at densities where the mean lattice site occupation is close to unity.

  12. The StaggerGrid Project: a Grid of 3D Model Atmospheres for High-Precision Spectroscopy

    CERN Document Server

    Collet, Remo; Asplund, Martin

    2011-01-01

    In this contribution, we present the StaggerGrid, a collaborative project for the construction of a comprehensive grid of time-dependent, three-dimensional (3D), hydrodynamic model atmospheres of solar- and late-type stars with different effective temperatures, surface gravities, and chemical compositions. We illustrate the main characteristics of these 3D models and their effects on the predicted strengths, wavelength-shifts, and shapes of spectral lines, highlighting the differences with respect to calculations based on classical, one-dimensional, hydrostatic models, and discuss some of their possible applications to elemental abundance analysis of stellar spectra in the context of large observational surveys.

  13. IZDELAVA TISKALNIKA 3D

    OpenAIRE

    Brdnik, Lovro

    2015-01-01

    Diplomsko delo analizira trenutno stanje 3D tiskalnikov na trgu. Prikazan je razvoj in principi delovanja 3D tiskalnikov. Predstavljeni so tipi 3D tiskalnikov, njihove prednosti in slabosti. Podrobneje je predstavljena zgradba in delovanje koračnih motorjev. Opravljene so meritve koračnih motorjev. Opisana je programska oprema za rokovanje s 3D tiskalniki in komponente, ki jih potrebujemo za izdelavo. Diploma se oklepa vprašanja, ali je izdelava 3D tiskalnika bolj ekonomična kot pa naložba v ...

  14. Lagrangian 3D particle tracking in high-speed flows: Shake-The-Box for multi-pulse systems

    Science.gov (United States)

    Novara, Matteo; Schanz, Daniel; Reuther, Nico; Kähler, Christian J.; Schröder, Andreas

    2016-08-01

    The Shake-The-Box (STB) particle tracking technique, recently introduced for time-resolved 3D particle image velocimetry (PIV) images, is applied here to data from a multi-pulse investigation of a turbulent boundary layer flow with adverse pressure gradient in air at 36 m/s ( Re τ = 10,650). The multi-pulse acquisition strategy allows for the recording of four-pulse long time-resolved sequences with a time separation of a few microseconds. The experimental setup consists of a dual-imaging system and a dual-double-cavity laser emitting orthogonal polarization directions to separate the four pulses. The STB particle triangulation and tracking strategy is adapted here to cope with the limited amount of realizations available along the time sequence and to take advantage of the ghost track reduction offered by the use of two independent imaging systems. Furthermore, a correction scheme to compensate for camera vibrations is discussed, together with a method to accurately identify the position of the wall within the measurement domain. Results show that approximately 80,000 tracks can be instantaneously reconstructed within the measurement volume, enabling the evaluation of both dense velocity fields, suitable for spatial gradients evaluation, and highly spatially resolved boundary layer profiles. Turbulent boundary layer profiles obtained from ensemble averaging of the STB tracks are compared to results from 2D-PIV and long-range micro particle tracking velocimetry; the comparison shows the capability of the STB approach in delivering accurate results across a wide range of scales.

  15. 3D tissue-engineered construct analysis via conventional high-resolution microcomputed tomography without X-ray contrast.

    Science.gov (United States)

    Voronov, Roman S; VanGordon, Samuel B; Shambaugh, Robert L; Papavassiliou, Dimitrios V; Sikavitsas, Vassilios I

    2013-05-01

    As the field of tissue engineering develops, researchers are faced with a large number of degrees of freedom regarding the choice of material, architecture, seeding, and culturing. To evaluate the effectiveness of a tissue-engineered strategy, histology is typically done by physically slicing and staining a construct (crude, time-consuming, and unreliable). However, due to recent advances in high-resolution biomedical imaging, microcomputed tomography (μCT) has arisen as a quick and effective way to evaluate samples, while preserving their structure in the original state. However, a major barrier for using μCT to do histology has been its inability to differentiate between materials with similar X-ray attenuation. Various contrasting strategies (hardware and chemical staining agents) have been proposed to address this problem, but at a cost of additional complexity and limited access. Instead, here we suggest a strategy for how virtual 3D histology in silico can be conducted using conventional μCT, and we provide an illustrative example from bone tissue engineering. The key to our methodology is an implementation of scaffold surface architecture that is ordered in relation to cells and tissue, in concert with straightforward image-processing techniques, to minimize the reliance on contrasting for material segmentation. In the case study reported, μCT was used to image and segment porous poly(lactic acid) nonwoven fiber mesh scaffolds that were seeded dynamically with mesenchymal stem cells and cultured to produce soft tissue and mineralized tissue in a flow perfusion bioreactor using an osteogenic medium. The methodology presented herein paves a new way for tissue engineers to identify and distinguish components of cell/tissue/scaffold constructs to easily and effectively evaluate the tissue-engineering strategies that generate them.

  16. Highly-flexible 3D Li2S/graphene cathode for high-performance lithium sulfur batteries

    Science.gov (United States)

    He, Jiarui; Chen, Yuanfu; Lv, Weiqiang; Wen, Kechun; Li, Pingjian; Qi, Fei; Wang, Zegao; Zhang, Wanli; Li, Yanrong; Qin, Wu; He, Weidong

    2016-09-01

    Three-dimensional Li2S/graphene hierarchical architecture (3DLG) is synthesized with a facile infiltration method. Highly-crystalline Li2S nanoparticles are deposited homogenously into three-dimensional graphene foam (3DGF) network grown by chemical vapor deposition (CVD), resulting in 3DLG with high surface area, porosity, flexibility and conductivity. The 3DLG is employed as flexible, free-standing and binder-free cathode without metallic current collectors or conducting additives. Due to the unique structure, the 3DLG exhibits a high discharge capacity of 894.7 mAh g-1 at 0.1 C, a high capacity retention of 87.7% after 300 cycles at 0.2 C, and the high-rate capacity up to 4 C reaches 598.6 mAh g-1. The cyclic performance is record-breaking compared to the previous reports on free-standing graphene-Li2S cathodes. Flexible lithium-sulfur batteries based on the high-capacity 3DLG cathode have promising application potentials in flexible electronics, electrical vehicles, etc.

  17. Comparative analysis of 2D and 3D dosimetry with brachytherapy high dose rate cervix carcinoma un operated

    International Nuclear Information System (INIS)

    It has recently been installed in our department based on an SPB CT images, and found that the dose at points H is less than that obtained by calculations based on radiographs. This study aims to analyze this discrepancy in the transition from 2D to 3D calculation in patients with carcinoma of the cervix not operated.

  18. Reconstruction of high-resolution 3D dose from matrix measurements : error detection capability of the COMPASS correction kernel method

    NARCIS (Netherlands)

    Godart, J.; Korevaar, E. W.; Visser, R.; Wauben, D. J. L.; van t Veld, Aart

    2011-01-01

    TheCOMPASS system (IBADosimetry) is a quality assurance (QA) tool which reconstructs 3D doses inside a phantom or a patient CT. The dose is predicted according to the RT plan with a correction derived from 2D measurements of a matrix detector. This correction method is necessary since a direct recon

  19. Characterization of a high resolution and high sensitivity pre-clinical PET scanner with 3D event reconstruction

    CERN Document Server

    Rissi, M; Bolle, E; Dorholt, O; Hines, K E; Rohne, O; Skretting, A; Stapnes, S; Volgyes, D

    2012-01-01

    COMPET is a preclinical PET scanner aiming towards a high sensitivity, a high resolution and MRI compatibility by implementing a novel detector geometry. In this approach, long scintillating LYSO crystals are used to absorb the gamma-rays. To determine the point of interaction (P01) between gamma-ray and crystal, the light exiting the crystals on one of the long sides is collected with wavelength shifters (WLS) perpendicularly arranged to the crystals. This concept has two main advantages: (1) The parallax error is reduced to a minimum and is equal for the whole field of view (FOV). (2) The P01 and its energy deposit is known in all three dimension with a high resolution, allowing for the reconstruction of Compton scattered gamma-rays. Point (1) leads to a uniform point source resolution (PSR) distribution over the whole FOV, and also allows to place the detector close to the object being imaged. Both points (1) and (2) lead to an increased sensitivity and allow for both high resolution and sensitivity at the...

  20. High Frequency Chandler Wobble Excitation

    Science.gov (United States)

    Seitz, F.; Stuck, J.; Thomas, M.

    2003-04-01

    and OMCT forcing fields give no hint for increased excitation power in the Chandler band. Thus it is assumed, that continuous high frequency excitation due to stochastic weather phenomena is responsible for the perpetuation of the Chandler wobble.

  1. 3D Printing of Graphene Aerogels.

    Science.gov (United States)

    Zhang, Qiangqiang; Zhang, Feng; Medarametla, Sai Pradeep; Li, Hui; Zhou, Chi; Lin, Dong

    2016-04-01

    3D printing of a graphene aerogel with true 3D overhang structures is highlighted. The aerogel is fabricated by combining drop-on-demand 3D printing and freeze casting. The water-based GO ink is ejected and freeze-cast into designed 3D structures. The lightweight (<10 mg cm(-3) ) 3D printed graphene aerogel presents superelastic and high electrical conduction.

  2. TOWARDS: 3D INTERNET

    Directory of Open Access Journals (Sweden)

    Ms. Swapnali R. Ghadge

    2013-08-01

    Full Text Available In today’s ever-shifting media landscape, it can be a complex task to find effective ways to reach your desired audience. As traditional media such as television continue to lose audience share, one venue in particular stands out for its ability to attract highly motivated audiences and for its tremendous growth potential the 3D Internet. The concept of '3D Internet' has recently come into the spotlight in the R&D arena, catching the attention of many people, and leading to a lot of discussions. Basically, one can look into this matter from a few different perspectives: visualization and representation of information, and creation and transportation of information, among others. All of them still constitute research challenges, as no products or services are yet available or foreseen for the near future. Nevertheless, one can try to envisage the directions that can be taken towards achieving this goal. People who take part in virtual worlds stay online longer with a heightened level of interest. To take advantage of that interest, diverse businesses and organizations have claimed an early stake in this fast-growing market. They include technology leaders such as IBM, Microsoft, and Cisco, companies such as BMW, Toyota, Circuit City, Coca Cola, and Calvin Klein, and scores of universities, including Harvard, Stanford and Penn State.

  3. 3D and Education

    Science.gov (United States)

    Meulien Ohlmann, Odile

    2013-02-01

    Today the industry offers a chain of 3D products. Learning to "read" and to "create in 3D" becomes an issue of education of primary importance. 25 years professional experience in France, the United States and Germany, Odile Meulien set up a personal method of initiation to 3D creation that entails the spatial/temporal experience of the holographic visual. She will present some different tools and techniques used for this learning, their advantages and disadvantages, programs and issues of educational policies, constraints and expectations related to the development of new techniques for 3D imaging. Although the creation of display holograms is very much reduced compared to the creation of the 90ies, the holographic concept is spreading in all scientific, social, and artistic activities of our present time. She will also raise many questions: What means 3D? Is it communication? Is it perception? How the seeing and none seeing is interferes? What else has to be taken in consideration to communicate in 3D? How to handle the non visible relations of moving objects with subjects? Does this transform our model of exchange with others? What kind of interaction this has with our everyday life? Then come more practical questions: How to learn creating 3D visualization, to learn 3D grammar, 3D language, 3D thinking? What for? At what level? In which matter? for whom?

  4. High Frequency Electronic Packaging Technology

    Science.gov (United States)

    Herman, M.; Lowry, L.; Lee, K.; Kolawa, E.; Tulintseff, A.; Shalkhauser, K.; Whitaker, J.; Piket-May, M.

    1994-01-01

    Commercial and government communication, radar, and information systems face the challenge of cost and mass reduction via the application of advanced packaging technology. A majority of both government and industry support has been focused on low frequency digital electronics.

  5. Handbook of 3D integration

    CERN Document Server

    Garrou , Philip; Ramm , Peter

    2014-01-01

    Edited by key figures in 3D integration and written by top authors from high-tech companies and renowned research institutions, this book covers the intricate details of 3D process technology.As such, the main focus is on silicon via formation, bonding and debonding, thinning, via reveal and backside processing, both from a technological and a materials science perspective. The last part of the book is concerned with assessing and enhancing the reliability of the 3D integrated devices, which is a prerequisite for the large-scale implementation of this emerging technology. Invaluable reading fo

  6. 3D Object Visual Tracking for the 220 kV/330 kV High-Voltage Live-Line Insulator Cleaning Robot

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jian; YANG Ru-qing

    2009-01-01

    The 3D object visual tracking problem is studied for the robot vision system of the 220 kV/330 kV high-voltage live-line insulator cleaning robot. The SUSAN Edge based Scale Invariant Feature (SESIF) algorithm based 3D objects visual tracking is achieved in three stages: the first frame stage, tracking stage, and recovering stage. An SESIF based objects recognition algorithm is proposed to fred initial location at both the first frame stage and recovering stage. An SESIF and Lie group based visual tracking algorithm is used to track 3D object. Experiments verify the algorithm's robustness. This algorithm will be used in the second generation of the 220 kV/330 kV high-voltage five-line insulator cleaning robot.

  7. High-performance III-V MOSFET with nano-stacked high-k gate dielectric and 3D fin-shaped structure.

    Science.gov (United States)

    Chen, Szu-Hung; Liao, Wen-Shiang; Yang, Hsin-Chia; Wang, Shea-Jue; Liaw, Yue-Gie; Wang, Hao; Gu, Haoshuang; Wang, Mu-Chun

    2012-01-01

    A three-dimensional (3D) fin-shaped field-effect transistor structure based on III-V metal-oxide-semiconductor field-effect transistor (MOSFET) fabrication has been demonstrated using a submicron GaAs fin as the high-mobility channel. The fin-shaped channel has a thickness-to-width ratio (TFin/WFin) equal to 1. The nano-stacked high-k Al2O3 dielectric was adopted as a gate insulator in forming a metal-oxide-semiconductor structure to suppress gate leakage. The 3D III-V MOSFET exhibits outstanding gate controllability and shows a high Ion/Ioff ratio > 105 and a low subthreshold swing of 80 mV/decade. Compared to a conventional Schottky gate metal-semiconductor field-effect transistor or planar III-V MOSFETs, the III-V MOSFET in this work exhibits a significant performance improvement and is promising for future development of high-performance n-channel devices based on III-V materials. PMID:22853458

  8. Direct growth of single-crystal Pt nanowires on Sn@CNT Nanocable: 3D electrodes for highly active electrocatalysts.

    Science.gov (United States)

    Sun, Shuhui; Zhang, Gaixia; Geng, Dongsheng; Chen, Yougui; Banis, Mohammad Norouzi; Li, Ruying; Cai, Mei; Sun, Xueliang

    2010-01-18

    A newly designed and fabricated novel three dimensional (3D) nanocomposite composed of single-crystal Pt nanowires (PtNW) and a coaxial nanocable support consisting of a tin nanowire and a carbon nanotube (Sn@CNT) is reported. This nanocomposite is fabricated by the synthesis of Sn@CNT nanocables by means of a thermal evaporation method, followed by the direct growth with PtNWs through a facile aqueous solution approach at room temperature. Electrochemical measurements demonstrate that the PtNW--Sn@CNT 3D electrode exhibits enhanced electrocatalytic performance in oxygen reduction reaction (ORR) for polymer electrolyte membrane fuel cells (PEMFCs), methanol oxidation (MOR) for direct methanol fuel cells (DMFCs), and CO tolerance compared with commercial ETEK Pt/C catalyst made of Pt nanoparticles. PMID:20024993

  9. Viral Infection at High Magnification: 3D Electron Microscopy Methods to Analyze the Architecture of Infected Cells.

    Science.gov (United States)

    Romero-Brey, Inés; Bartenschlager, Ralf

    2015-12-01

    As obligate intracellular parasites, viruses need to hijack their cellular hosts and reprogram their machineries in order to replicate their genomes and produce new virions. For the direct visualization of the different steps of a viral life cycle (attachment, entry, replication, assembly and egress) electron microscopy (EM) methods are extremely helpful. While conventional EM has given important information about virus-host cell interactions, the development of three-dimensional EM (3D-EM) approaches provides unprecedented insights into how viruses remodel the intracellular architecture of the host cell. During the last years several 3D-EM methods have been developed. Here we will provide a description of the main approaches and examples of innovative applications.

  10. 3-D Video Processing for 3-D TV

    Science.gov (United States)

    Sohn, Kwanghoon; Kim, Hansung; Kim, Yongtae

    One of the most desirable ways of realizing high quality information and telecommunication services has been called "The Sensation of Reality," which can be achieved by visual communication based on 3-D (Three-dimensional) images. These kinds of 3-D imaging systems have revealed potential applications in the fields of education, entertainment, medical surgery, video conferencing, etc. Especially, three-dimensional television (3-D TV) is believed to be the next generation of TV technology. Figure 13.1 shows how TV's display technologies have evolved , and Fig. 13.2 details the evolution of TV broadcasting as forecasted by the ETRI (Electronics and Telecommunications Research Institute). It is clear that 3-D TV broadcasting will be the next development in this field, and realistic broadcasting will soon follow.

  11. Process development for the manufacturing of flat knitted innovative 3D spacer fabrics for high performance composite applications

    OpenAIRE

    Abounaim, Md.

    2011-01-01

    Innovative 3D spacer fabrics made from individual planes and connecting layers present great potential as complexly shaped textile preforms in lightweight composite applications. As one of the most flexible textile manufacturing methods, flat knitting enables the production of intricately shaped textile structures. The major advantages coupled with flat knitting techniques include the ability to produce multi-layer reinforcements, a diminishing waste, reducing production time and near-net sha...

  12. A Numerical Study on the Thermal Conductivity of 3D Woven C/C Composites at High Temperature

    Science.gov (United States)

    Shigang, Ai; Rujie, He; Yongmao, Pei

    2015-12-01

    Experimental data for Carbon/Carbon (C/C) constituent materials are combined with a three dimensional steady state heat transfer finite element analysis to demonstrate the average in-plane and out-of-plane thermal conductivities (TCs) of C/C composites. The finite element analysis is carried out at two distinct length scales: (a) a micro scale comparable with the diameter of carbon fibres and (b) a meso scale comparable with the carbon fibre yarns. Micro-scale model calculate the TCs at the fibre yarn scale in the three orthogonal directions ( x, y and z). The output results from the micro-scale model are then incorporated in the meso-scale model to obtain the global TCs of the 3D C/C composite. The simulation results are quite consistent with the theoretical and experimental counterparts reported in references. Based on the numerical approach, TCs of the 3D C/C composite are calculated from 300 to 2500 K. Particular attention is given in elucidating the variations of the TCs with temperature. The multi-scale models provide an efficient approach to predict the TCs of 3D textile materials, which is helpful for the thermodynamic property analysis and structure design of the C/C composites.

  13. Feasibility and evaluation of dual-source transmit 3D imaging of the orbits: Comparison to high-resolution conventional MRI at 3T

    Energy Technology Data Exchange (ETDEWEB)

    Seeger, Achim, E-mail: achim.seeger@gmx.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Schulze, Maximilian, E-mail: maximilian.schulze@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Schuettauf, Frank, E-mail: fschuettauf@uni-tuebingen.de [University Eye Hospital, Department of Ophthalmology, Eberhard-Karls-University, Schleichstrasse 12, Tübingen 72076 (Germany); Klose, Uwe, E-mail: uwe.klose@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Ernemann, Ulrike, E-mail: ulrike.ernemann@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Hauser, Till-Karsten, E-mail: till-karsten.hauser@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany)

    2015-06-15

    Highlights: • Reduced FOV imaging enables a 3D approach for a very fast assessment of the orbits. • Conventional MRI exhibited higher eSNR values and consecutively higher scores for overall image quality in the subjective readers’ analysis. • All pathologies could be detected compared to high-resolution conventional MRI making 3D pTX SPACE to a potential alternative and fast imaging technique. - Abstract: Purpose: To prospectively compare the image quality and diagnostic performance of orbital MR images obtained by using a dual-source parallel transmission (pTX) 3D sequence (Sampling Perfection with Application optimized Contrasts using different flip angle Evolution, SPACE) with the image quality of conventional high-resolution standard protocol for clinical use in patients at 3T. Materials and methods: After obtaining institutional review board approval and patient consent, 32 patients with clinical indication for orbital MRI were examined using a high-resolution conventional sequences and 3D pTX SPACE sequences. Quantitative measurements, image quality of the healthy orbit, incidence of artifacts, and the subjective diagnostic performance to establish diagnosis was rated. Statistical significance was calculated by using a Student's t-test and nonparametric Wilcoxon signed rank test. Results: Length measurements were comparable in the two techniques, 3D pTX SPACE resulted in significant faster image acquisition with higher spatial resolution and less motion artifacts as well as better delineation of the optic nerve sheath. However, estimated contrast-to-noise and signal-to-noise and overall image quality as well as subjective scores of the conventional TSE imaging were rated significantly higher. The conventional MR sequences were the preferred techniques by the readers. Conclusion: This study demonstrates the feasibility of 3D pTX SPACE of the orbit resulting in a rapid acquisition of isotropic high-resolution images. Although no pathology was

  14. High resolution 3D ERT to help GPR data interpretation for researching archaeological items in a geologically complex subsurface

    Science.gov (United States)

    Negri, S.; Leucci, G.; Mazzone, F.

    2008-09-01

    Muro Leccese (Lecce) contains one the most important Messapian archaeological sites in southern Italy. The archaeological interest of the site arises from the discovery of the remains of Messapian walls, tombs, roads, etc. (4th-2nd centuries BC) in the neighbourhood. The archaeological remains were found at about 0.3 m depth. At present the site belongs to the municipality, which intends to build a new sewer network through it. The risk of destroying potentially interesting ancient archaeological structures during the works prompted an archaeological survey of the area. The relatively large dimensions of the area (almost 10,000 m 2), together with time and cost constraints, made it necessary to use geophysical investigations as a faster means to ascertain the presence of archaeological items. Since the most important targets were expected to be located at a soil depth of about 0.3 m, a ground-penetrating radar (GPR) survey was carried out in an area located near the archaeological excavations. Unfortunately the geological complexity did not allow an easy interpretation of the GPR data. Therefore a 3D electrical resistivity tomography (ERT) scan was conducted in order to resolve these interpretation problems. A three-way comparison of the results of the dense ERT measurements parallel to the x axis, the results of the measurements parallel to the y axis and the combined results was performed. Subsequently the synthetic model approach was used to provide a better characterization of the resistivity anomalies visible on the ERT field data. The 3D inversion results clearly illustrate the capability to resolve in view of quality 3D structures of archaeological interest. According to the presented data the inversion models along one direction ( x or y) seems to be adequate in reconstructing the subsurface structures. Naturally field data produce good quality reconstructions of the archaeological features only if the x-line and y-line measurements are considered together

  15. Studies on image quality, high contrast resolution and dose for the axial skeleton and limbs with a new, dedicated CT system (ISO-C-3D)

    International Nuclear Information System (INIS)

    Purpose: Evaluation of 3D-CT imaging of the axial skeleton and different joints of the lower and upper extremities with a new dedicated CT system (ISO-C-3D) based on a mobile isocentric C-arm image amplifier. Material and Methods: 27 cadaveric specimes of different joints of the lower and upper extremities and of the spinal column were examined with 3D-CT imaging (ISO-C-3d). All images were evaluated by 3 radiologists for image quality using a semiquantitative score (score value 1: poor quality; score value 4: excellent quality). In addition, dose measurements and measurements of high contrast resolution were performed in comparison to conventional and low-dose spiral CT using a high contrast phantom (Catphan, Phantom Laboratories). Results: Adequate image quality (mean score values 3-4) could be achieved with an applied dose comparable to low-dose CT in smaller joints such as wrist, elbow, ankle and knee. A remarkably inferior image quality resulted in imaging of the hip, lumbar and thoracic spine (mean score values 2-3) in spite of almost doubling the dose (dose increased by 85 percent). The image quality of shoulder examinations was insufficient (mean score value 1). Phantom studies showed a high-contrast resolution comparable to helical CT in the xy-axis (9 lp/cm). Conclusion: Preliminary results show, that image quality of C-arm-based CT-imaging (ISO-C-3D) seems to be adequate in smaller joints. ISO-C-3D images of the hip and axial skeleton show a decreased image quality, which does not seem to be sufficient for diagnosing subtle fractures. (orig.)

  16. Application of high-precision 3D seismic technology to shale gas exploration: A case study of the large Jiaoshiba shale gas field in the Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Zuqing Chen

    2016-03-01

    Full Text Available The accumulation pattern of the marine shale gas in South China is different from that in North America. The former has generally thin reservoirs and complex preservation conditions, so it is difficult to make a fine description of the structural features of shale formations and to reflect accurately the distribution pattern of high-quality shale by using the conventional 2D and 3D seismic exploration technology, which has an adverse effect on the successful deployment of horizontal wells. In view of this, high-precision 3D seismic prospecting focusing on lithological survey was implemented to make an accurate description of the distribution of shale gas sweet spots so that commercial shale gas production can be obtained. Therefore, due to the complex seismic geological condition of Jiaoshiba area in Fuling, SE Sichuan Basin, the observation system of high-precision 3D seismic acquisition should have such features as wide-azimuth angles, small trace intervals, high folds, uniform vertical and horizontal coverage and long spread to meet the needs of the shale gas exploration in terms of structural interpretation, lithological interpretation and fracture prediction. Based on this idea, the first implemented high-precision 3D seismic exploration project in Jiaoshiba area played an important role in the discovery of the large Jiaoshiba shale gas field. Considering that the high-quality marine shale in the Sichuan Basin shows the characteristics of multi-layer development from the Silurian system to the Cambrian system, the strategy of shale gas stereoscopic exploration should be implemented to fully obtain the oil and gas information of the shallow, medium and deep strata from the high-precision 3D seismic data, and ultimately to expand the prospecting achievements in an all-round way to balance the high upstream exploration cost, and to continue to push the efficient shale gas exploration and development process in China.

  17. A Novel 3D Thermal Impedance Model for High Power Modules Considering Multi-layer Thermal Coupling and Different Heating/Cooling Conditions

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2015-01-01

    accurate temperature estimation either vertically or horizontally inside the power devices is still hard to identify. This paper investigates the thermal behavior of high power module in various operating conditions by means of Finite Element Method (FEM). A novel 3D thermal impedance network considering...

  18. 3D virtuel udstilling

    DEFF Research Database (Denmark)

    Tournay, Bruno; Rüdiger, Bjarne

    2006-01-01

    3d digital model af Arkitektskolens gård med virtuel udstilling af afgangsprojekter fra afgangen sommer 2006. 10 s.......3d digital model af Arkitektskolens gård med virtuel udstilling af afgangsprojekter fra afgangen sommer 2006. 10 s....

  19. High Temporal and Spatial Resolution 3D Time-Resolved Contrast-Enhanced MR Angiography of the Hands and Feet

    OpenAIRE

    Haider, Clifton R.; Riederer, Stephen J.; Borisch, Eric A.; Glockner, James F; Grimm, Roger C.; Hulshizer, Thomas C.; Macedo, Thanila A.; Mostardi, Petrice M.; Rossman, Phillip J.; Vrtiska, Terri J.; Young, Phillip M.

    2011-01-01

    Methods are described for generating 3D time-resolved contrast-enhanced MR angiograms of the hands and feet. Given targeted spatial resolution and frame times, it is shown that acceleration of about one order of magnitude or more is necessary. This is obtained by a combination of 2D Sensitivity Encoding (SENSE) and homodyne (HD) acceleration methods. Image update times from 3.4 to 6.8 sec are provided in conjunction with view sharing. Modular receiver coil arrays are described which can be de...

  20. High frequency pressure oscillator for microcryocoolers

    NARCIS (Netherlands)

    Vanapalli, S.; Brake, ter H.J.M.; Jansen, H.V.; Zhao, Y.; Holland, H.J.; Burger, J.F.; Elwenspoek, M.C.

    2008-01-01

    Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pre

  1. Transponder System for High-Frequency Ranging

    Science.gov (United States)

    Lichtenberg, C. L.; Shores, P. W.; Kobayashi, H. S.

    1986-01-01

    Transponder system uses phase difference between transmitted and reflected high-frequency radio waves to measure distance to target. To suppress spurious measurements of reflections from objects near target at transmitted frequency and its harmonics, transponder at target generates return signal at half transmitted frequency. System useful in such applications as surveying, docking of ships, and short-range navigation.

  2. High-Throughput Cancer Cell Sphere Formation for Characterizing the Efficacy of Photo Dynamic Therapy in 3D Cell Cultures

    Science.gov (United States)

    Chen, Yu-Chih; Lou, Xia; Zhang, Zhixiong; Ingram, Patrick; Yoon, Euisik

    2015-07-01

    Photodynamic therapy (PDT), wherein light sensitive non-toxic agents are locally and selectively activated using light, has emerged as an appealing alternative to traditional cancer chemotherapy. Yet to date, PDT efficacy has been mostly characterized using 2D cultures. Compared to 2D cultures, 3D sphere culture generates unique spatial distributions of nutrients and oxygen for the cells that better mimics the in-vivo conditions. Using a novel polyHEMA (non-adherent polymer) fabrication process, we developed a microfluidic sphere formation platform that can (1) generate 1,024 uniform (size variation cancer spheres within a 2 cm by 2 cm core area, (2) culture spheres for more than 2 weeks, and (3) allow the retrieval of spheres. Using the presented platform, we have successfully characterized the different responses in 2D and 3D cell culture to PDT. Furthermore, we investigated the treatment resistance effect in cancer cells induced by tumor associated fibroblasts (CAF). Although the CAFs can enhance the resistance to traditional chemotherapy agents, no significant difference in PDT was observed. The preliminary results suggest that the PDT can be an attractive alternative cancer therapy, which is less affected by the therapeutic resistance induced by cancer associated cells.

  3. 3-D flexible nano-textured high-density microelectrode arrays for high-performance neuro-monitoring and neuro-stimulation.

    Science.gov (United States)

    Gabran, S R I; Salam, Muhammad Tariqus; Dian, Joshua; El-Hayek, Youssef; Perez Velazquez, J L; Genov, Roman; Carlen, Peter L; Salama, M M A; Mansour, Raafat R

    2014-09-01

    We introduce a new 3-D flexible microelectrode array for high performance electrographic neural signal recording and stimulation. The microelectrode architecture maximizes the number of channels on each shank and minimizes its footprint. The electrode was implemented on flexible polyimide substrate using microfabrication and thin-film processing. The electrode has a planar layout and comprises multiple shanks. Each shank is three mm in length and carries six gold pads representing the neuro-interfacing channels. The channels are used in recording important precursors with potential clinical relevance and consequent electrical stimulation to perturb the clinical condition. The polyimide structure satisfied the mechanical characteristics required for the proper electrode implantation and operation. Pad postprocessing technique was developed to improve the electrode electrical performance. The planar electrodes were used for creating 3-D "Waterloo Array" microelectrode with controlled gaps using custom designed stackers. Electrode characterization and benchmarking against commercial equivalents demonstrated the superiority of the Flex electrodes. The Flex and commercial electrodes were associated with low-power implantable responsive neuro-stimulation system. The electrodes performance in recording and stimulation application was quantified through in vitro and in vivo acute and chronic experiments on human brain slices and freely-moving rodents. The Flex electrodes exhibited remarkable drop in the electric impedance (100 times at 100 Hz), improved electrode-electrolyte interface noise (dropped by four times) and higher signal-to-noise ratio (3.3 times). PMID:24876130

  4. Low voltage operation of electro-absorption modulator promising for high-definition 3D imaging application using a three step asymmetric coupled quantum well structure

    International Nuclear Information System (INIS)

    In this paper, we propose a transmission type electro-absorption modulator (EAM) operating at 850 nm having low operating voltage and high absorption change with low insertion loss using a novel three step asymmetric coupled quantum well (3 ACQW) structure which can be used as an optical image shutter for high-definition (HD) three dimensional (3D) imaging. Theoretical calculations show that the exciton red shift of 3 ACQW structure is more than two times larger than that of rectangular quantum well (RQW) structure while maintaining high absorption change. The EAM having coupled cavities with 3 ACQW structure shows a wide spectral bandwidth and high amplitude modulation at a bias voltage of only -8V, which is 41% lower in operating voltage than that of RQW, making the proposed EAM highly attractive as an optical image shutter for HD 3D imaging applications

  5. High-dose radiotherapy in inoperable nonsmall cell lung cancer: comparison of volumetric modulated arc therapy, dynamic IMRT and 3D conformal radiotherapy.

    Science.gov (United States)

    Bree, Ingrid de; van Hinsberg, Mariëlle G E; van Veelen, Lieneke R

    2012-01-01

    Conformal 3D radiotherapy (3D-CRT) combined with chemotherapy for inoperable non-small cell lung cancer (NSCLC) to the preferable high dose is often not achievable because of dose-limiting organs. This reduces the probability of regional tumor control. Therefore, the surplus value of using intensity-modulated radiation therapy (IMRT) techniques, specifically volumetric modulated arc therapy (RapidArc [RA]) and dynamic IMRT (d-IMRT) has been investigated. RA and d-IMRT plans were compared with 3D-CRT treatment plans for 20 patients eligible for concurrent high-dose chemoradiotherapy, in whom a dose of 60 Gy was not achievable. Comparison of dose delivery in the target volume and organs at risk was carried out by evaluating 3D dose distributions and dose-volume histograms. Quality of the dose distribution was assessed using the inhomogeneity and conformity index. For most patients, a higher dose to the target volume can be delivered using RA or d-IMRT; in 15% of the patients a dose ≥60 Gy was possible. Both IMRT techniques result in a better conformity of the dose (p < 0.001). There are no significant differences in homogeneity of dose in the target volume. IMRT techniques for NSCLC patients allow higher dose to the target volume, thus improving regional tumor control. PMID:22459649

  6. High-dose radiotherapy in inoperable nonsmall cell lung cancer: Comparison of volumetric modulated arc therapy, dynamic IMRT and 3D conformal radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Bree, Ingrid de, E-mail: i.de.bree@zrti.nl [Zeeuws Radiotherapeutisch Instituut, Vlissingen (Netherlands); Hinsberg, Marieelle G.E. van; Veelen, Lieneke R. van [Zeeuws Radiotherapeutisch Instituut, Vlissingen (Netherlands)

    2012-01-01

    Conformal 3D radiotherapy (3D-CRT) combined with chemotherapy for inoperable non-small cell lung cancer (NSCLC) to the preferable high dose is often not achievable because of dose-limiting organs. This reduces the probability of regional tumor control. Therefore, the surplus value of using intensity-modulated radiation therapy (IMRT) techniques, specifically volumetric modulated arc therapy (RapidArc [RA]) and dynamic IMRT (d-IMRT) has been investigated. RA and d-IMRT plans were compared with 3D-CRT treatment plans for 20 patients eligible for concurrent high-dose chemoradiotherapy, in whom a dose of 60 Gy was not achievable. Comparison of dose delivery in the target volume and organs at risk was carried out by evaluating 3D dose distributions and dose-volume histograms. Quality of the dose distribution was assessed using the inhomogeneity and conformity index. For most patients, a higher dose to the target volume can be delivered using RA or d-IMRT; in 15% of the patients a dose {>=}60 Gy was possible. Both IMRT techniques result in a better conformity of the dose (p < 0.001). There are no significant differences in homogeneity of dose in the target volume. IMRT techniques for NSCLC patients allow higher dose to the target volume, thus improving regional tumor control.

  7. High-dose radiotherapy in inoperable nonsmall cell lung cancer: Comparison of volumetric modulated arc therapy, dynamic IMRT and 3D conformal radiotherapy

    International Nuclear Information System (INIS)

    Conformal 3D radiotherapy (3D-CRT) combined with chemotherapy for inoperable non–small cell lung cancer (NSCLC) to the preferable high dose is often not achievable because of dose-limiting organs. This reduces the probability of regional tumor control. Therefore, the surplus value of using intensity-modulated radiation therapy (IMRT) techniques, specifically volumetric modulated arc therapy (RapidArc [RA]) and dynamic IMRT (d-IMRT) has been investigated. RA and d-IMRT plans were compared with 3D-CRT treatment plans for 20 patients eligible for concurrent high-dose chemoradiotherapy, in whom a dose of 60 Gy was not achievable. Comparison of dose delivery in the target volume and organs at risk was carried out by evaluating 3D dose distributions and dose-volume histograms. Quality of the dose distribution was assessed using the inhomogeneity and conformity index. For most patients, a higher dose to the target volume can be delivered using RA or d-IMRT; in 15% of the patients a dose ≥60 Gy was possible. Both IMRT techniques result in a better conformity of the dose (p < 0.001). There are no significant differences in homogeneity of dose in the target volume. IMRT techniques for NSCLC patients allow higher dose to the target volume, thus improving regional tumor control.

  8. 3D high resolution mineral phase distribution and seismic velocity structure of the transition zone: predicted by a full spherical-shell compressible mantle convection model

    Science.gov (United States)

    Geenen, T.; Heister, T.; Van Den Berg, A. P.; Jacobs, M.; Bangerth, W.

    2011-12-01

    We present high resolution 3D results of the complex mineral phase distribution in the transition zone obtained by numerical modelling of mantle convection. We extend the work by [Jacobs and van den Berg, 2011] to 3D and illustrate the efficiency of adaptive mesh refinement for capturing the complex spatial distribution and sharp phase transitions as predicted by their model. The underlying thermodynamical model is based on lattice dynamics which allows to predict thermophysical properties and seismic wave speeds for the applied magnesium-endmember olivine-pyroxene mineralogical model. The use of 3D geometry allows more realistic prediction of phase distribution and seismic wave speeds resulting from 3D flow processes involving the Earth's transition zone and more significant comparisons with interpretations from seismic tomography and seismic reflectivity studies aimed at the transition zone. Model results are generated with a recently developed geodynamics modeling application based on dealII (www.dealii.org). We extended this model to incorporate both a general thermodynamic model, represented by P,T space tabulated thermophysical properties, and a solution strategy that allows for compressible flow. When modeling compressible flow in the so called truncated anelastic approximation framework we have to adapt the solver strategy that has been proven by several authors to be highly efficient for incompressible flow to incorporate an extra term in the continuity equation. We present several possible solution strategies and discuss their implication in terms of robustness and computational efficiency.

  9. Fabrication of Highly Stretchable Conductors Based on 3D Printed Porous Poly(dimethylsiloxane) and Conductive Carbon Nanotubes/Graphene Network.

    Science.gov (United States)

    Duan, Shasha; Yang, Ke; Wang, Zhihui; Chen, Mengting; Zhang, Ling; Zhang, Hongbo; Li, Chunzhong

    2016-01-27

    The combination of carbon nanomaterial with three-dimensional (3D) porous polymer substrates has been demonstrated to be an effective approach to manufacture high-performance stretchable conductive materials (SCMs). However, it remains a challenge to fabricate 3D-structured SCMs with outstanding electrical conductivity capability under large strain in a facile way. In this work, the 3D printing technique was employed to prepare 3D porous poly(dimethylsiloxane) (O-PDMS) which was then integrated with carbon nanotubes and graphene conductive network and resulted in highly stretchable conductors (OPCG). Two types of OPCG were prepared, and it has been demonstrated that the OPCG with split-level structure exhibited both higher electrical conductivity and superior retention capability under deformations, which was illustrated by using a finite element method. The specially designed split-level OPCG is capable of sustaining both large strain and repeated deformations showing huge potential in the application of next-generation stretchable electronics. PMID:26713456

  10. Blender 3D cookbook

    CERN Document Server

    Valenza, Enrico

    2015-01-01

    This book is aimed at the professionals that already have good 3D CGI experience with commercial packages and have now decided to try the open source Blender and want to experiment with something more complex than the average tutorials on the web. However, it's also aimed at the intermediate Blender users who simply want to go some steps further.It's taken for granted that you already know how to move inside the Blender interface, that you already have 3D modeling knowledge, and also that of basic 3D modeling and rendering concepts, for example, edge-loops, n-gons, or samples. In any case, it'

  11. Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing and simultaneous acquisition of chemical shift correlation spectra

    Energy Technology Data Exchange (ETDEWEB)

    Bellstedt, Peter [Fritz Lipmann Institute, Biomolecular NMR spectroscopy, Leibniz Institute for Age Research (Germany); Herbst, Christian [Ubon Ratchathani University, Department of Physics, Faculty of Science (Thailand); Haefner, Sabine; Leppert, Joerg; Goerlach, Matthias; Ramachandran, Ramadurai, E-mail: raman@fli-leibniz.de [Fritz Lipmann Institute, Biomolecular NMR spectroscopy, Leibniz Institute for Age Research (Germany)

    2012-12-15

    We have carried out chemical shift correlation experiments with symmetry-based mixing sequences at high MAS frequencies and examined different strategies to simultaneously acquire 3D correlation spectra that are commonly required in the structural studies of proteins. The potential of numerically optimised symmetry-based mixing sequences and the simultaneous recording of chemical shift correlation spectra such as: 3D NCAC and 3D NHH with dual receivers, 3D NC Prime C and 3D C Prime NCA with sequential {sup 13}C acquisitions, 3D NHH and 3D NC Prime H with sequential {sup 1}H acquisitions and 3D CANH and 3D C'NH with broadband {sup 13}C-{sup 15}N mixing are demonstrated using microcrystalline samples of the {beta}1 immunoglobulin binding domain of protein G (GB1) and the chicken {alpha}-spectrin SH3 domain.

  12. Kondo effect at low electron density and high particle-hole asymmetry in 1D, 2D, and 3D

    Science.gov (United States)

    Žitko, Rok; Horvat, Alen

    2016-09-01

    Using the perturbative scaling equations and the numerical renormalization group, we study the characteristic energy scales in the Kondo impurity problem as a function of the exchange coupling constant J and the conduction-band electron density. We discuss the relation between the energy gain (impurity binding energy) Δ E and the Kondo temperature TK. We find that the two are proportional only for large values of J , whereas in the weak-coupling limit the energy gain is quadratic in J , while the Kondo temperature is exponentially small. The exact relation between the two quantities depends on the detailed form of the density of states of the band. In the limit of low electron density the Kondo screening is affected by the strong particle-hole asymmetry due to the presence of the band-edge van Hove singularities. We consider the cases of one- (1D), two- (2D), and three-dimensional (3D) tight-binding lattices (linear chain, square lattice, cubic lattice) with inverse-square-root, step-function, and square-root onsets of the density of states that are characteristic of the respective dimensionalities. We always find two different regimes depending on whether TK is higher or lower than μ , the chemical potential measured from the bottom of the band. For 2D and 3D, we find a sigmoidal crossover between the large-J and small-J asymptotics in Δ E and a clear separation between Δ E and TK for TKband edge. Furthermore, we find that in 1D the particle-hole asymmetry leads to a large decrease of TK compared to the standard result obtained by approximating the density of states to be constant (flat-band approximation), while in 3D the opposite is the case; this is due to the nontrivial interplay of the exchange and potential scattering renormalization in the presence of particle-hole asymmetry. The 2D square-lattice density of states behaves to a very good approximation as a band with constant density of states.

  13. High Temporal and Spatial Resolution 3D Time-Resolved Contrast-Enhanced MR Angiography of the Hands and Feet

    Science.gov (United States)

    Haider, Clifton R.; Riederer, Stephen J.; Borisch, Eric A.; Glockner, James F.; Grimm, Roger C.; Hulshizer, Thomas C.; Macedo, Thanila A.; Mostardi, Petrice M.; Rossman, Phillip J.; Vrtiska, Terri J.; Young, Phillip M.

    2010-01-01

    Methods are described for generating 3D time-resolved contrast-enhanced MR angiograms of the hands and feet. Given targeted spatial resolution and frame times, it is shown that acceleration of about one order of magnitude or more is necessary. This is obtained by a combination of 2D Sensitivity Encoding (SENSE) and homodyne (HD) acceleration methods. Image update times from 3.4 to 6.8 sec are provided in conjunction with view sharing. Modular receiver coil arrays are described which can be designed to the targeted vascular region. Images representative of the technique are generated in the vasculature of the hands and feet in volunteers and in patient studies. PMID:21698702

  14. High-Temperature Processing of Solids Through Solar Nebular Bow Shocks: 3D Radiation Hydrodynamics Simulations with Particles

    CERN Document Server

    Boley, A C; Desch, S J

    2013-01-01

    A fundamental, unsolved problem in Solar System formation is explaining the melting and crystallization of chondrules found in chondritic meteorites. Theoretical models of chondrule melting in nebular shocks has been shown to be consistent with many aspects of thermal histories inferred for chondrules from laboratory experiments; but, the mechanism driving these shocks is unknown. Planetesimals and planetary embryos on eccentric orbits can produce bow shocks as they move supersonically through the disk gas, and are one possible source of chondrule-melting shocks. We investigate chondrule formation in bow shocks around planetoids through 3D radiation hydrodynamics simulations. A new radiation transport algorithm that combines elements of flux-limited diffusion and Monte Carlo methods is used to capture the complexity of radiative transport around bow shocks. An equation of state that includes the rotational, vibrational, and dissociation modes of H$_2$ is also used. Solids are followed directly in the simulati...

  15. Electro-optical microwave signal processor for high-frequency wideband frequency channelization

    Science.gov (United States)

    Dawber, William N.; Webster, Ken

    1998-08-01

    An electro-optic microwave signal processor for activity monitoring in an electronic warfare receiver, offering wideband operation, parallel output in real time and 100 percent probability of intercept is presented, along with results from a prototype system. Requirements on electronic warfare receiver system are demanding, because they have to defect and identify potential threats across a large frequency bandwidth and in the high pulse density expected of the battlefield environment. A technique of processing signals across a wide bandwidth is to use a channelizer in the receiver front-end, in order to produce a number of narrow band outputs that can be individually processed. In the presented signal processor, received microwave signals ar unconverted onto an optical carrier using an electro- optic modulator and then spatially separated into a series of spots. The position and intensity of the spots is determined by the received signal(s) frequency and strength. Finally a photodiode array can be used for fast parallel data readout. Thus the signal processor output is fully channelized according to frequency. A prototype signal processor has been constructed, which can process microwave frequencies from 500MHz to 8GHz. A standard telecommunications electro-optic intensity modulator with a 3dB bandwidth of approximately 2.5GHz provides frequency upconversion. Readout is achieved using either a near IR camera or a 16 element linear photodiode array.

  16. Influence of extremely low frequency, low energy electromagnetic fields and combined mechanical stimulation on chondrocytes in 3-D constructs for cartilage tissue engineering.

    Science.gov (United States)

    Hilz, Florian M; Ahrens, Philipp; Grad, Sibylle; Stoddart, Martin J; Dahmani, Chiheb; Wilken, Frauke L; Sauerschnig, Martin; Niemeyer, Philipp; Zwingmann, Jörn; Burgkart, Rainer; von Eisenhart-Rothe, Rüdiger; Südkamp, Norbert P; Weyh, Thomas; Imhoff, Andreas B; Alini, Mauro; Salzmann, Gian M

    2014-02-01

    Articular cartilage, once damaged, has very low regenerative potential. Various experimental approaches have been conducted to enhance chondrogenesis and cartilage maturation. Among those, non-invasive electromagnetic fields have shown their beneficial influence for cartilage regeneration and are widely used for the treatment of non-unions, fractures, avascular necrosis and osteoarthritis. One very well accepted way to promote cartilage maturation is physical stimulation through bioreactors. The aim of this study was the investigation of combined mechanical and electromagnetic stress affecting cartilage cells in vitro. Primary articular chondrocytes from bovine fetlock joints were seeded into three-dimensional (3-D) polyurethane scaffolds and distributed into seven stimulated experimental groups. They either underwent mechanical or electromagnetic stimulation (sinusoidal electromagnetic field of 1 mT, 2 mT, or 3 mT; 60 Hz) or both within a joint-specific bioreactor and a coil system. The scaffold-cell constructs were analyzed for glycosaminoglycan (GAG) and DNA content, histology, and gene expression of collagen-1, collagen-2, aggrecan, cartilage oligomeric matrix protein (COMP), Sox9, proteoglycan-4 (PRG-4), and matrix metalloproteinases (MMP-3 and -13). There were statistically significant differences in GAG/DNA content between the stimulated versus the control group with highest levels in the combined stimulation group. Gene expression was significantly higher for combined stimulation groups versus static control for collagen 2/collagen 1 ratio and lower for MMP-13. Amongst other genes, a more chondrogenic phenotype was noticed in expression patterns for the stimulated groups. To conclude, there is an effect of electromagnetic and mechanical stimulation on chondrocytes seeded in a 3-D scaffold, resulting in improved extracellular matrix production.

  17. Martian terrain - 3D

    Science.gov (United States)

    1997-01-01

    This area of terrain near the Sagan Memorial Station was taken on Sol 3 by the Imager for Mars Pathfinder (IMP). 3D glasses are necessary to identify surface detail.The IMP is a stereo imaging system with color capability provided by 24 selectable filters -- twelve filters per 'eye.' It stands 1.8 meters above the Martian surface, and has a resolution of two millimeters at a range of two meters.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.Click below to see the left and right views individually. [figure removed for brevity, see original site] Left [figure removed for brevity, see original site] Right

  18. Retrodirective Antenna Array Using High Frequency Offset

    Directory of Open Access Journals (Sweden)

    P. Sindler

    2012-12-01

    Full Text Available The paper deals with the design of a simple retrodirective antenna array exhibiting by high frequency offset between received and transmitted wave. Analysis of the beam pointing error using antenna array model developed in MATLAB is described. The frequencies of transmitted wave and received wave are chosen on the basis of this analysis. Then a suitable structure for further design is determined and particular blocks of complete retrodirective antenna array are briefly described and their measured parameters are presented. Relatively high frequency offset between received and transmitted wave makes it possible to use frequency filters for received and transmitted signal separation which led to significant reduction of the circuit complexity.

  19. MPML3D: Scripting Agents for the 3D Internet.

    Science.gov (United States)

    Prendinger, Helmut; Ullrich, Sebastian; Nakasone, Arturo; Ishizuka, Mitsuru

    2011-05-01

    The aim of this paper is two-fold. First, it describes a scripting language for specifying communicative behavior and interaction of computer-controlled agents ("bots") in the popular three-dimensional (3D) multiuser online world of "Second Life" and the emerging "OpenSimulator" project. While tools for designing avatars and in-world objects in Second Life exist, technology for nonprogrammer content creators of scenarios involving scripted agents is currently missing. Therefore, we have implemented new client software that controls bots based on the Multimodal Presentation Markup Language 3D (MPML3D), a highly expressive XML-based scripting language for controlling the verbal and nonverbal behavior of interacting animated agents. Second, the paper compares Second Life and OpenSimulator platforms and discusses the merits and limitations of each from the perspective of agent control. Here, we also conducted a small study that compares the network performance of both platforms.

  20. Comparative analysis of 2D and 3D dosimetry with brachytherapy high dose rate cervix carcinoma un operated; Analisis comparativo de dosimetria 2D y 3D con braquiterapia de alta tasa de dosis

    Energy Technology Data Exchange (ETDEWEB)

    Garcia Castejon, M. A.; Penedo Cobos, J. M.; Rincon Perez, M.; Gomez Alonso, S.; Luna Tirado, J.; Perez Casas, A. M.

    2011-07-01

    It has recently been installed in our department based on an SPB CT images, and found that the dose at points H is less than that obtained by calculations based on radiographs. This study aims to analyze this discrepancy in the transition from 2D to 3D calculation in patients with carcinoma of the cervix not operated.

  1. SU-E-CAMPUS-T-05: Validation of High-Resolution 3D Patient QA for Proton Pencil Beam Scanning and IMPT by Polymer Gel Dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Cardin, A; Avery, S; Ding, X; Kassaee, A; Lin, L [University of Pennsylvania, Philadelphia, PA (United States); Maryanski, M [MGS Research, Inc., Madison, CT (United States)

    2014-06-15

    Purpose: Validation of high-resolution 3D patient QA for proton pencil beam scanning and IMPT by polymer gel dosimetry. Methods: Four BANG3Pro polymer gel dosimeters (manufactured by MGS Research Inc, Madison, CT) were used for patient QA at the Robert's Proton Therapy Center (RPTC, Philadelphia, PA). All dosimeters were sealed in identical thin-wall Pyrex glass spheres. Each dosimeter contained a set of markers for 3D registration purposes. The dosimeters were mounted in a consistent and reproducible manner using a custom build holder. Two proton pencil beam scanning plans were designed using Varian Eclipse™ treatment planning system: 1) A two-field intensity modulated proton therapy (IMPT) plan and 2) one single field uniform dose (SFUD) plan. The IMPT fields were evaluated as a composite plan and individual fields, the SFUD plan was delivered as a single field plan.Laser CT scanning was performed using the manufacturer's OCTOPUS-IQ axial transmission laser CT scanner using a 1 mm slice thickness. 3D registration, analysis, and OD/cm to absorbed dose calibrations were perfomed using DICOM RT-Dose and CT files, and software developed by the manufacturer. 3D delta index, a metric equivalent to the gamma tool, was used for dose comparison. Results: Very good agreement with single IMPT fields and with SFUD was obtained. Composite IMPT fields had a less satisfactory agreement. The single fields had 3D delta index passing rates (3% dose difference, 3 mm DTA) of 98.98% and 94.91%. The composite 3D delta index passing rate was 80.80%. The SFUD passing rate was 93.77%. Required shifts of the dose distributions were less than 4 mm. Conclusion: A formulation of the BANG3Pro polymer gel dosimeter, suitable for 3D QA of proton patient plans is established and validated. Likewise, the mailed QA analysis service provided by the manufacturer is a practical option when required resources are unavailable. We fully disclose that the subject of this research regards a

  2. High frequency group pulse electrochemical machining

    Institute of Scientific and Technical Information of China (English)

    WU Gaoyang; ZHANG Zhijing; ZHANG Weimin; TANG Xinglun

    2007-01-01

    In the process of machining ultrathin metal structure parts,the signal composition of high frequency group pulse,the influence of frequency to reverse current,and the design of the cathode in high frequency group pulse electrochemical machining (HGPECM) are discussed.The experiments on process were carried out.Results indicate that HGPECM can greatly improve the characteristics of the inter-electrode gap flow field,reduce electrode passivation,and obtain high machining quality.The machining quality is obviously improved by increasing the main pulse frequency.The dimensional accuracy reaches 30-40 pro and the roughness attained is at 0.30-0.35 μm.High frequency group pulse electrochemical machining can be successfully used in machining micro-parts.

  3. Ultra-high frequency magnetic resonance imaging

    OpenAIRE

    Magill, Arthur W.

    2007-01-01

    This thesis addresses the problem of radiofrequency probe design for Ultra High Frequency Magnetic Resonance Imaging (7T). The signal-to-noise ratio available in Magnetic Resonance Imaging (MRI) is determined by the static magnetic field strength, causing a continued drive toward higher fields to enable faster image acquisition at finer spatial resolution. The resonant frequency increases linearly with static field strength. At 7T the proton resonant frequency is 300MHz, with a wavelength...

  4. Ultra-High-Frequency Capacitive Displacement Sensor

    Science.gov (United States)

    Vanzandt, Thomas R.; Kenny, Thomas W.; Kaiser, William J.

    1994-01-01

    Improved class of compact, high-resolution capacitive displacement sensors operates at excitation frequency of 915 MHz and measures about 7.5 by 4 by 2 centimeters. Contains commercially available 915-MHz oscillator and transmission-line resonator. Resonator contains stripline inductor in addition to variable capacitor. Ultrahigh excitation frequency offers advantages of resolution and frequency response. Not deleteriously affected by mechanical overdriving, or contact between electrodes.

  5. Novel 3D media technologies

    CERN Document Server

    Dagiuklas, Tasos

    2015-01-01

    This book describes recent innovations in 3D media and technologies, with coverage of 3D media capturing, processing, encoding, and adaptation, networking aspects for 3D Media, and quality of user experience (QoE). The contributions are based on the results of the FP7 European Project ROMEO, which focuses on new methods for the compression and delivery of 3D multi-view video and spatial audio, as well as the optimization of networking and compression jointly across the future Internet. The delivery of 3D media to individual users remains a highly challenging problem due to the large amount of data involved, diverse network characteristics and user terminal requirements, as well as the user’s context such as their preferences and location. As the number of visual views increases, current systems will struggle to meet the demanding requirements in terms of delivery of consistent video quality to fixed and mobile users. ROMEO will present hybrid networking solutions that combine the DVB-T2 and DVB-NGH broadcas...

  6. 3D future internet media

    CERN Document Server

    Dagiuklas, Tasos

    2014-01-01

    This book describes recent innovations in 3D media and technologies, with coverage of 3D media capturing, processing, encoding, and adaptation, networking aspects for 3D Media, and quality of user experience (QoE). The main contributions are based on the results of the FP7 European Projects ROMEO, which focus on new methods for the compression and delivery of 3D multi-view video and spatial audio, as well as the optimization of networking and compression jointly across the Future Internet (www.ict-romeo.eu). The delivery of 3D media to individual users remains a highly challenging problem due to the large amount of data involved, diverse network characteristics and user terminal requirements, as well as the user’s context such as their preferences and location. As the number of visual views increases, current systems will struggle to meet the demanding requirements in terms of delivery of constant video quality to both fixed and mobile users. ROMEO will design and develop hybrid-networking solutions that co...

  7. Engineering 3D bicontinuous hierarchically macro-mesoporous LiFePO4/C nanocomposite for lithium storage with high rate capability and long cycle stability

    Science.gov (United States)

    Zhang, Qian; Huang, Shao-Zhuan; Jin, Jun; Liu, Jing; Li, Yu; Wang, Hong-En; Chen, Li-Hua; Wang, Bin-Jie; Su, Bao-Lian

    2016-01-01

    A highly crystalline three dimensional (3D) bicontinuous hierarchically macro-mesoporous LiFePO4/C nanocomposite constructed by nanoparticles in the range of 50~100 nm via a rapid microwave assisted solvothermal process followed by carbon coating have been synthesized as cathode material for high performance lithium-ion batteries. The abundant 3D macropores allow better penetration of electrolyte to promote Li+ diffusion, the mesopores provide more electrochemical reaction sites and the carbon layers outside LiFePO4 nanoparticles increase the electrical conductivity, thus ultimately facilitating reverse reaction of Fe3+ to Fe2+ and alleviating electrode polarization. In addition, the particle size in nanoscale can provide short diffusion lengths for the Li+ intercalation-deintercalation. As a result, the 3D macro-mesoporous nanosized LiFePO4/C electrode exhibits excellent rate capability (129.1 mA h/g at 2 C; 110.9 mA h/g at 10 C) and cycling stability (87.2% capacity retention at 2 C after 1000 cycles, 76.3% at 5 C after 500 cycles and 87.8% at 10 C after 500 cycles, respectively), which are much better than many reported LiFePO4/C structures. Our demonstration here offers the opportunity to develop nanoscaled hierarchically porous LiFePO4/C structures for high performance lithium-ion batteries through microwave assisted solvothermal method. PMID:27181195

  8. Engineering 3D bicontinuous hierarchically macro-mesoporous LiFePO4/C nanocomposite for lithium storage with high rate capability and long cycle stability

    Science.gov (United States)

    Zhang, Qian; Huang, Shao-Zhuan; Jin, Jun; Liu, Jing; Li, Yu; Wang, Hong-En; Chen, Li-Hua; Wang, Bin-Jie; Su, Bao-Lian

    2016-05-01

    A highly crystalline three dimensional (3D) bicontinuous hierarchically macro-mesoporous LiFePO4/C nanocomposite constructed by nanoparticles in the range of 50~100 nm via a rapid microwave assisted solvothermal process followed by carbon coating have been synthesized as cathode material for high performance lithium-ion batteries. The abundant 3D macropores allow better penetration of electrolyte to promote Li+ diffusion, the mesopores provide more electrochemical reaction sites and the carbon layers outside LiFePO4 nanoparticles increase the electrical conductivity, thus ultimately facilitating reverse reaction of Fe3+ to Fe2+ and alleviating electrode polarization. In addition, the particle size in nanoscale can provide short diffusion lengths for the Li+ intercalation-deintercalation. As a result, the 3D macro-mesoporous nanosized LiFePO4/C electrode exhibits excellent rate capability (129.1 mA h/g at 2 C; 110.9 mA h/g at 10 C) and cycling stability (87.2% capacity retention at 2 C after 1000 cycles, 76.3% at 5 C after 500 cycles and 87.8% at 10 C after 500 cycles, respectively), which are much better than many reported LiFePO4/C structures. Our demonstration here offers the opportunity to develop nanoscaled hierarchically porous LiFePO4/C structures for high performance lithium-ion batteries through microwave assisted solvothermal method.

  9. Development of High Frequency Miniature Ultrasound Transducers

    OpenAIRE

    Manh, Tung

    2013-01-01

    Small, high frequency (≥ 10MHz) broadband ultrasound transducers are required in modern medical imaging systems to provide short range, high resolution images for studying of microstructures in soft tissues, such as the composition of small tumors or a vessel wall. The manufacturing of these probes using conventional methods, i.e. lapping and dicing, becomes difficult and expensive for high frequency applications and there is a need to produce small ultrasound transducers with low cost and hi...

  10. 78 FR 70567 - Nationwide Use of High Frequency and Ultra High Frequency Active SONAR Technology; Final...

    Science.gov (United States)

    2013-11-26

    ... SECURITY Coast Guard Nationwide Use of High Frequency and Ultra High Frequency Active SONAR Technology...) and Ultra High Frequency (UHF) Sound Navigation and Ranging (SONAR) Technology and Finding of No Significant Impact (FONSI). The USCG is proposing the nationwide use of active SONAR technologies that...

  11. Markerless 3D Face Tracking

    DEFF Research Database (Denmark)

    Walder, Christian; Breidt, Martin; Bulthoff, Heinrich;

    2009-01-01

    We present a novel algorithm for the markerless tracking of deforming surfaces such as faces. We acquire a sequence of 3D scans along with color images at 40Hz. The data is then represented by implicit surface and color functions, using a novel partition-of-unity type method of efficiently...... combining local regressors using nearest neighbor searches. Both these functions act on the 4D space of 3D plus time, and use temporal information to handle the noise in individual scans. After interactive registration of a template mesh to the first frame, it is then automatically deformed to track...... the scanned surface, using the variation of both shape and color as features in a dynamic energy minimization problem. Our prototype system yields high-quality animated 3D models in correspondence, at a rate of approximately twenty seconds per timestep. Tracking results for faces and other objects...

  12. Radiochromic 3D Detectors

    Science.gov (United States)

    Oldham, Mark

    2015-01-01

    Radiochromic materials exhibit a colour change when exposed to ionising radiation. Radiochromic film has been used for clinical dosimetry for many years and increasingly so recently, as films of higher sensitivities have become available. The two principle advantages of radiochromic dosimetry include greater tissue equivalence (radiologically) and the lack of requirement for development of the colour change. In a radiochromic material, the colour change arises direct from ionising interactions affecting dye molecules, without requiring any latent chemical, optical or thermal development, with important implications for increased accuracy and convenience. It is only relatively recently however, that 3D radiochromic dosimetry has become possible. In this article we review recent developments and the current state-of-the-art of 3D radiochromic dosimetry, and the potential for a more comprehensive solution for the verification of complex radiation therapy treatments, and 3D dose measurement in general.

  13. 3D Projection Installations

    DEFF Research Database (Denmark)

    Halskov, Kim; Johansen, Stine Liv; Bach Mikkelsen, Michelle

    2014-01-01

    Three-dimensional projection installations are particular kinds of augmented spaces in which a digital 3-D model is projected onto a physical three-dimensional object, thereby fusing the digital content and the physical object. Based on interaction design research and media studies, this article...... contributes to the understanding of the distinctive characteristics of such a new medium, and identifies three strategies for designing 3-D projection installations: establishing space; interplay between the digital and the physical; and transformation of materiality. The principal empirical case, From...... Fingerplan to Loop City, is a 3-D projection installation presenting the history and future of city planning for the Copenhagen area in Denmark. The installation was presented as part of the 12th Architecture Biennale in Venice in 2010....

  14. Genotoxic Effects of Low- and High-LET Radiation on Human Epithelial Cells Grown in 2-D Versus 3-D Culture

    Science.gov (United States)

    Patel, Z. S.; Cucinotta, F. A.; Huff, J. L.

    2011-01-01

    Risk estimation for radiation-induced cancer relies heavily on human epidemiology data obtained from terrestrial irradiation incidents from sources such as medical and occupational exposures as well as from the atomic bomb survivors. No such data exists for exposures to the types and doses of high-LET radiation that will be encountered during space travel; therefore, risk assessment for space radiation requires the use of data derived from cell culture and animal models. The use of experimental models that most accurately replicate the response of human tissues is critical for precision in risk projections. This work compares the genotoxic effects of radiation on normal human epithelial cells grown in standard 2-D monolayer culture compared to 3-D organotypic co-culture conditions. These 3-D organotypic models mimic the morphological features, differentiation markers, and growth characteristics of fully-differentiated normal human tissue and are reproducible using defined components. Cultures were irradiated with 2 Gy low-LET gamma rays or varying doses of high-LET particle radiation and genotoxic damage was measured using a modified cytokinesis block micronucleus assay. Our results revealed a 2-fold increase in residual damage in 2 Gy gamma irradiated cells grown under organotypic culture conditions compared to monolayer culture. Irradiation with high-LET particle radiation gave similar results, while background levels of damage were comparable under both scenarios. These observations may be related to the phenomenon of "multicellular resistance" where cancer cells grown as 3-D spheroids or in vivo exhibit an increased resistance to killing by chemotherapeutic agents compared to the same cells grown in 2-D culture. A variety of factors are likely involved in mediating this process, including increased cell-cell communication, microenvironment influences, and changes in cell cycle kinetics that may promote survival of damaged cells in 3-D culture that would

  15. Annual to sub-annual 3D surface evolution of an Antarctic blue-ice moraine using multi-platform, multi-temporal high resolution topography

    Science.gov (United States)

    Westoby, Matthew; Dunning, Stuart; Woodward, John; Hein, Andrew; Marrero, Shasta; Winter, Kate; Sugden, David

    2016-04-01

    High-resolution topographic data products are now routinely used for the geomorphological characterisation of Earth surface landforms and landscapes, whilst the acquisition and differencing of such datasets are swiftly becoming the preferred method for quantifying the transfer of mass through landscapes at the spatial scales of observation at which many processes operate. In this research, we employ 3-D differencing of repeat high-resolution topography to quantify the surface evolution of a 0.3 km2 blue-ice moraine complex in front of Patriot Hills, Antarctica. We used terrestrial laser scanning (TLS) to acquire multiple overlapping 3D datasets of the moraine surface at the beginning and end of the austral summer season in 2012/2013 and during a resurvey campaign in 2014. An additional topographic dataset was acquired at the end of season 1 through the application of a Structure-from-Motion with Multi-View Stereo (SfM-MVS) workflow to a set of aerial photographs acquired during a single unmanned aerial vehicle (UAV) sortie. 3D cloud-to-cloud differencing was undertaken using the M3C2 algorithm. The results of 3D differencing revealed net uplift (median ~0.05 m) and lateral (xy) movement (median 0.02 m) of the moraine crests within season 1. Analysis of results from the longest differencing epoch (start of season 1 to season 2) suggests gradual but persistent surface uplift (median ~0.11 m) and sustained lateral movement (median ~0.05 m). Locally, lowering of a similar magnitude to uplift was observed in inter-moraine troughs and close to the current ice margin. This research demonstrates that it is possible to detect dynamic surface topographic change across glacial moraines over short timescales through the acquisition and differencing of high-resolution topographic datasets. Such data and methods of analysis offer new opportunities to understand glaciological and geomorphological process linkages in remote glacial environments.

  16. High frequency dynamics in centrifugal compressors

    NARCIS (Netherlands)

    Twerda, A.; Meulendijks, D.; Smeulers, J.P.M.; Handel, R. van den; Lier, L.J. van

    2008-01-01

    Problems with centrifugal compressors relating to high frequency, i.e. Blade passing frequency (BPF) are increasing. Pulsations and vibrations generated in centrifugal compressors can lead to nuisance, due to strong tonal noise, and even breakdown. In several cases the root cause of a failure or a n

  17. Herramientas SIG 3D

    Directory of Open Access Journals (Sweden)

    Francisco R. Feito Higueruela

    2010-04-01

    Full Text Available Applications of Geographical Information Systems on several Archeology fields have been increasing during the last years. Recent avances in these technologies make possible to work with more realistic 3D models. In this paper we introduce a new paradigm for this system, the GIS Thetrahedron, in which we define the fundamental elements of GIS, in order to provide a better understanding of their capabilities. At the same time the basic 3D characteristics of some comercial and open source software are described, as well as the application to some samples on archeological researchs

  18. Bootstrapping 3D fermions

    Science.gov (United States)

    Iliesiu, Luca; Kos, Filip; Poland, David; Pufu, Silviu S.; Simmons-Duffin, David; Yacoby, Ran

    2016-03-01

    We study the conformal bootstrap for a 4-point function of fermions in 3D. We first introduce an embedding formalism for 3D spinors and compute the conformal blocks appearing in fermion 4-point functions. Using these results, we find general bounds on the dimensions of operators appearing in the ψ × ψ OPE, and also on the central charge C T . We observe features in our bounds that coincide with scaling dimensions in the GrossNeveu models at large N . We also speculate that other features could coincide with a fermionic CFT containing no relevant scalar operators.

  19. Interaktiv 3D design

    DEFF Research Database (Denmark)

    Villaume, René Domine; Ørstrup, Finn Rude

    2002-01-01

    Projektet undersøger potentialet for interaktiv 3D design via Internettet. Arkitekt Jørn Utzons projekt til Espansiva blev udviklet som et byggesystem med det mål, at kunne skabe mangfoldige planmuligheder og mangfoldige facade- og rumudformninger. Systemets bygningskomponenter er digitaliseret som...... 3D elementer og gjort tilgængelige. Via Internettet er det nu muligt at sammenstille og afprøve en uendelig  række bygningstyper som  systemet blev tænkt og udviklet til....

  20. 3D Printing: Exploring Capabilities

    Science.gov (United States)

    Samuels, Kyle; Flowers, Jim

    2015-01-01

    As 3D printers become more affordable, schools are using them in increasing numbers. They fit well with the emphasis on product design in technology and engineering education, allowing students to create high-fidelity physical models to see and test different iterations in their product designs. They may also help students to "think in three…

  1. The approximate analysis of the electromagnetic characters of 3-D radome by complex astigmatic wave theory

    Science.gov (United States)

    Wang, Yueqing; Wu, Guisheng; Chen, Zhenyang

    The complex astigmatic wave, which imitates the 3-D beam in high-frequency, is an effective method to analyze the electromagnetic characters of the 3-D arbitrarily curved radome. A number of calculations for the ellipsoidal sandwich radome are performed, and the stereoscopic graphics of the results are constructed. Comparing with the experiments, it is shown that this method can be used to simplify analysis and optimization design for many kinds of 3-D radome.

  2. Performance Analysis of a 3D Ionosphere Tomographic Model

    Institute of Scientific and Technical Information of China (English)

    Liu Zhi-zhao; Gao Yang

    2003-01-01

    A 3D high precision ionospheric model is developed based on tomography technique. This tomographic model employs GPS data observed by an operational network of dual-frequency GPS receivers. The methodology of developing a 3D ionospheric tomography model is briefly summarized. However emphasis is put on the analysis and evaluation of the accuracy variation of 3D ionosphere modeling with respect to the change of GPS data cutoff angle.Three typical cutoff angle values (15°, 20° and 25°) are tested. For each testing cutoff angle, the performances of the3D ionospheric model constructed using tomography technique are assessed by calibrating the model predicted ionospheric TEC with the GPS measured TEC and by employing the model predicted TEC to a practical GPS positioning application single point positioning (SPP).Test results indicate the 3D model predicted VTEC has about 0.4 TECU improvement in accuracy when cutoff angle rises from 15° to 20°. However, no apparent improvement is found from 20° to 25°. The model's improvement is also validated by the better SPP accuracy of 3D model than its counterpart-dual frequency model in the 20° and 25° cases.

  3. FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons

    Science.gov (United States)

    Bosch, Carles; Martínez, Albert; Masachs, Nuria; Teixeira, Cátia M.; Fernaud, Isabel; Ulloa, Fausto; Pérez-Martínez, Esther; Lois, Carlos; Comella, Joan X.; DeFelipe, Javier; Merchán-Pérez, Angel; Soriano, Eduardo

    2015-01-01

    The fine analysis of synaptic contacts is usually performed using transmission electron microscopy (TEM) and its combination with neuronal labeling techniques. However, the complex 3D architecture of neuronal samples calls for their reconstruction from serial sections. Here we show that focused ion beam/scanning electron microscopy (FIB/SEM) allows efficient, complete, and automatic 3D reconstruction of identified dendrites, including their spines and synapses, from GFP/DAB-labeled neurons, with a resolution comparable to that of TEM. We applied this technology to analyze the synaptogenesis of labeled adult-generated granule cells (GCs) in mice. 3D reconstruction of dendritic spines in GCs aged 3–4 and 8–9 weeks revealed two different stages of dendritic spine development and unexpected features of synapse formation, including vacant and branched dendritic spines and presynaptic terminals establishing synapses with up to 10 dendritic spines. Given the reliability, efficiency, and high resolution of FIB/SEM technology and the wide use of DAB in conventional EM, we consider FIB/SEM fundamental for the detailed characterization of identified synaptic contacts in neurons in a high-throughput manner. PMID:26052271

  4. FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons.

    Science.gov (United States)

    Bosch, Carles; Martínez, Albert; Masachs, Nuria; Teixeira, Cátia M; Fernaud, Isabel; Ulloa, Fausto; Pérez-Martínez, Esther; Lois, Carlos; Comella, Joan X; DeFelipe, Javier; Merchán-Pérez, Angel; Soriano, Eduardo

    2015-01-01

    The fine analysis of synaptic contacts is usually performed using transmission electron microscopy (TEM) and its combination with neuronal labeling techniques. However, the complex 3D architecture of neuronal samples calls for their reconstruction from serial sections. Here we show that focused ion beam/scanning electron microscopy (FIB/SEM) allows efficient, complete, and automatic 3D reconstruction of identified dendrites, including their spines and synapses, from GFP/DAB-labeled neurons, with a resolution comparable to that of TEM. We applied this technology to analyze the synaptogenesis of labeled adult-generated granule cells (GCs) in mice. 3D reconstruction of dendritic spines in GCs aged 3-4 and 8-9 weeks revealed two different stages of dendritic spine development and unexpected features of synapse formation, including vacant and branched dendritic spines and presynaptic terminals establishing synapses with up to 10 dendritic spines. Given the reliability, efficiency, and high resolution of FIB/SEM technology and the wide use of DAB in conventional EM, we consider FIB/SEM fundamental for the detailed characterization of identified synaptic contacts in neurons in a high-throughput manner.

  5. Extracellular vesicles of calcifying turkey leg tendon characterized by immunocytochemistry and high voltage electron microscopic tomography and 3-D graphic image reconstruction

    Science.gov (United States)

    Landis, W. J.; Hodgens, K. J.; McKee, M. D.; Nanci, A.; Song, M. J.; Kiyonaga, S.; Arena, J.; McEwen, B.

    1992-01-01

    To gain insight into the structure and possible function of extracellular vesicles in certain calcifying vertebrate tissues, normally mineralizing leg tendons from the domestic turkey, Meleagris gallopavo, have been studied in two separate investigations, one concerning the electron microscopic immunolocalization of the 66 kDa phosphoprotein, osteopontin, and the other detailing the organization and distribution of mineral crystals associated with the vesicles as determined by high voltage microscopic tomography and 3-D graphic image reconstruction. Immunolabeling shows that osteopontin is related to extracellular vesicles of the tendon in the sense that its initial presence appears coincident with the development of mineral associated with the vesicle loci. By high voltage electron microscopy and 3-D imaging techniques, mineral crystals are found to consist of small irregularly shaped particles somewhat randomly oriented throughout individual vesicles sites. Their appearance is different from that found for the mineral observed within calcifying tendon collagen, and their 3-D disposition is not regularly ordered. Possible spatial and temporal relationships of vesicles, osteopontin, mineral, and collagen are being examined further by these approaches.

  6. FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons

    Directory of Open Access Journals (Sweden)

    Carles eBosch

    2015-05-01

    Full Text Available The fine analysis of synaptic contacts is usually performed using transmission electron microscopy (TEM and its combination with neuronal labeling techniques. However, the complex 3D architecture of neuronal samples calls for their reconstruction from serial sections. Here we show that focused ion beam/scanning electron microscopy (FIB/SEM allows efficient, complete, and automatic 3D reconstruction of identified dendrites, including their spines and synapses, from GFP/DAB-labeled neurons, with a resolution comparable to that of TEM. We applied this technology to analyze the synaptogenesis of labeled adult-generated granule cells (GCs in mice. 3D reconstruction of spines in GCs aged 3–4 and 8–9 weeks revealed two different stages of spine development and unexpected features of synapse formation, including vacant and branched spines and presynaptic terminals establishing synapses with up to 10 spines. Given the reliability, efficiency, and high resolution of FIB/SEM technology and the wide use of DAB in conventional EM, we consider FIB/SEM fundamental for the detailed characterization of identified synaptic contacts in neurons in a high-throughput manner.

  7. Mapping the 3D distribution of CdSe nanocrystals in highly oriented and nanostructured hybrid P3HT-CdSe films grown by directional epitaxial crystallization.

    Science.gov (United States)

    Roiban, L; Hartmann, L; Fiore, A; Djurado, D; Chandezon, F; Reiss, P; Legrand, J-F; Doyle, S; Brinkmann, M; Ersen, O

    2012-11-21

    Highly oriented and nanostructured hybrid thin films made of regioregular poly(3-hexylthiophene) and colloidal CdSe nanocrystals are prepared by a zone melting method using epitaxial growth on 1,3,5-trichlorobenzene oriented crystals. The structure of the films has been analyzed by X-ray diffraction using synchrotron radiation, electron diffraction and 3D electron tomography to afford a multi-scale structural and morphological description of the highly structured hybrid films. A quantitative analysis of the reconstructed volumes based on electron tomography is used to establish a 3D map of the distribution of the CdSe nanocrystals in the bulk of the films. In particular, the influence of the P3HT-CdSe ratio on the 3D structure of the hybrid layers has been analyzed. In all cases, a bi-layer structure was observed. It is made of a first layer of pure oriented semi-crystalline P3HT grown epitaxially on the TCB substrate and a second P3HT layer containing CdSe nanocrystals uniformly distributed in the amorphous interlamellar zones of the polymer. The thickness of the P3HT layer containing CdSe nanoparticles increases gradually with increasing content of NCs in the films. A growth model is proposed to explain this original transversal organization of CdSe NCs in the oriented matrix of P3HT.

  8. WE-F-16A-04: Micro-Irradiator Treatment Verification with High-Resolution 3D-Printed Rodent-Morphic Dosimeters

    International Nuclear Information System (INIS)

    Purpose: Pre-clinical micro-radiation therapy studies often utilize very small beams (∼0.5-5mm), and require accurate dose delivery in order to effectively investigate treatment efficacy. Here we present a novel high-resolution absolute 3D dosimetry procedure, capable of ∼100-micron isotopic dosimetry in anatomically accurate rodent-morphic phantoms Methods: Anatomically accurate rat-shaped 3D dosimeters were made using 3D printing techniques from outer body contours and spinal contours outlined on CT. The dosimeters were made from a radiochromic plastic material PRESAGE, and incorporated high-Z PRESASGE inserts mimicking the spine. A simulated 180-degree spinal arc treatment was delivered through a 2 step process: (i) cone-beam-CT image-guided positioning was performed to precisely position the rat-dosimeter for treatment on the XRad225 small animal irradiator, then (ii) treatment was delivered with a simulated spine-treatment with a 180-degree arc with 20mm x 10mm cone at 225 kVp. Dose distribution was determined from the optical density change using a high-resolution in-house optical-CT system. Absolute dosimetry was enabled through calibration against a novel nano-particle scintillation detector positioned in a channel in the center of the distribution. Results: Sufficient contrast between regular PRESAGE (tissue equivalent) and high-Z PRESAGE (spinal insert) was observed to enable highly accurate image-guided alignment and targeting. The PRESAGE was found to have linear optical density (OD) change sensitivity with respect to dose (R2 = 0.9993). Absolute dose for 360-second irradiation at isocenter was found to be 9.21Gy when measured with OD change, and 9.4Gy with nano-particle detector- an agreement within 2%. The 3D dose distribution was measured at 500-micron resolution Conclusion: This work demonstrates for the first time, the feasibility of accurate absolute 3D dose measurement in anatomically accurate rat phantoms containing variable density PRESAGE

  9. WE-F-16A-04: Micro-Irradiator Treatment Verification with High-Resolution 3D-Printed Rodent-Morphic Dosimeters

    Energy Technology Data Exchange (ETDEWEB)

    Bache, S; Belley, M [Duke University Medical Physics Graduate Program, Durham, NC (United States); Benning, R; Adamovics, J [Rider University, Lawrenceville, NJ (United States); Stanton, I; Therien, M [Department of Chemistry, Duke University, Durham, NC (United States); Yoshizumi, T [Department of Radiology, Duke University Medical Center, Durham, NC (United States); Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Oldham, M [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States)

    2014-06-15

    Purpose: Pre-clinical micro-radiation therapy studies often utilize very small beams (∼0.5-5mm), and require accurate dose delivery in order to effectively investigate treatment efficacy. Here we present a novel high-resolution absolute 3D dosimetry procedure, capable of ∼100-micron isotopic dosimetry in anatomically accurate rodent-morphic phantoms Methods: Anatomically accurate rat-shaped 3D dosimeters were made using 3D printing techniques from outer body contours and spinal contours outlined on CT. The dosimeters were made from a radiochromic plastic material PRESAGE, and incorporated high-Z PRESASGE inserts mimicking the spine. A simulated 180-degree spinal arc treatment was delivered through a 2 step process: (i) cone-beam-CT image-guided positioning was performed to precisely position the rat-dosimeter for treatment on the XRad225 small animal irradiator, then (ii) treatment was delivered with a simulated spine-treatment with a 180-degree arc with 20mm x 10mm cone at 225 kVp. Dose distribution was determined from the optical density change using a high-resolution in-house optical-CT system. Absolute dosimetry was enabled through calibration against a novel nano-particle scintillation detector positioned in a channel in the center of the distribution. Results: Sufficient contrast between regular PRESAGE (tissue equivalent) and high-Z PRESAGE (spinal insert) was observed to enable highly accurate image-guided alignment and targeting. The PRESAGE was found to have linear optical density (OD) change sensitivity with respect to dose (R{sup 2} = 0.9993). Absolute dose for 360-second irradiation at isocenter was found to be 9.21Gy when measured with OD change, and 9.4Gy with nano-particle detector- an agreement within 2%. The 3D dose distribution was measured at 500-micron resolution Conclusion: This work demonstrates for the first time, the feasibility of accurate absolute 3D dose measurement in anatomically accurate rat phantoms containing variable density

  10. High Energy Single Frequency Resonant Amplifier Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR phase I project proposes a single frequency high energy resonant amplifier for remote sensing. Current state-of-art technologies can not provide all...

  11. BUILDING A HOMEMADE 3D PRINTER

    OpenAIRE

    Tunc, Baran

    2015-01-01

    3D printing has been attracted much attention around the world due to its high potential of new application fields. In this respect, developing and inventing new filament materials for 3D printers or new techniques of 3D printing are the main interest of the many materials scientists. This paper reports a comprehensive overview of 3D printing followed by a summary of my ongoing study of building a composite homemade 3D printer. At this stage of this study, a CNC router was successfully conver...

  12. Tangible 3D Modelling

    DEFF Research Database (Denmark)

    Hejlesen, Aske K.; Ovesen, Nis

    2012-01-01

    This paper presents an experimental approach to teaching 3D modelling techniques in an Industrial Design programme. The approach includes the use of tangible free form models as tools for improving the overall learning. The paper is based on lecturer and student experiences obtained through facil...

  13. 3D Harmonic Echocardiography:

    NARCIS (Netherlands)

    M.M. Voormolen

    2007-01-01

    textabstractThree dimensional (3D) echocardiography has recently developed from an experimental technique in the ’90 towards an imaging modality for the daily clinical practice. This dissertation describes the considerations, implementation, validation and clinical application of a unique

  14. Evaluation of 3D radio-frequency electromagnetic fields for any matching and coupling conditions by the use of basis functions

    Science.gov (United States)

    Tiberi, Gianluigi; Fontana, Nunzia; Monorchio, Agostino; Stara, Riccardo; Retico, Alessandra; Tosetti, Michela

    2015-12-01

    A procedure for evaluating radio-frequency electromagnetic fields in anatomical human models for any matching and coupling conditions is introduced. The procedure resorts to the extraction of basis functions: such basis functions, which represent the fields produced by each individual port without any residual coupling, are derived through an algebraic procedure which uses the S parameter matrix and the fields calculated in one (only) full-wave simulation. The basis functions are then used as building-blocks for calculating the fields for any other S parameter matrix. The proposed approach can be used both for volume coil driven in quadrature and for parallel transmission configuration.

  15. A capacitive DAC with custom 3-D 1-fF MOM unit capacitors optimized for fast-settling routing in high speed SAR ADCs

    Science.gov (United States)

    Chixiao, Chen; Jixuan, Xiang; Huabin, Chen; Jun, Xu; Fan, Ye; Ning, Li; Junyan, Ren

    2015-05-01

    Asynchronous successive approximation register (SAR) analog-to-digital converters (ADC) feature high energy efficiency but medium performance. From the point of view of speed, the key bottleneck is the unit capacitor size. In this paper, a small size three-dimensional (3-D) metal—oxide—metal (MOM) capacitor is proposed. The unit capacitor has a capacitance of 1-fF. It shapes as an umbrella, which is designed for fast settling consideration. A comparison among the proposed capacitor with other 3-D MOM capacitors is also given in the paper. To demonstrate the effectiveness of the MOM capacitor, a 6-b capacitive DAC is implemented in TSMC 1P9M 65 nm LP CMOS technology. The DAC consumes a power dissipation of 0.16 mW at the rate of 100 MS/s, excluding a source-follower based output buffer. Static measurement result shows that INL is less than ±1 LSB and DNL is less than ±0.5 LSB. In addition, a 100 MS/s 9-bit SAR ADC with the proposed 3-D capacitor is simulated.

  16. Topographic deformation patterns of knee cartilage after exercises with high knee flexion: an in vivo 3D MRI study using voxel-based analysis at 3T

    International Nuclear Information System (INIS)

    To implement a novel voxel-based technique to identify statistically significant local cartilage deformation and analyze in-vivo topographic knee cartilage deformation patterns using a voxel-based thickness map approach for high-flexion postures. Sagittal 3T 3D-T1w-FLASH-WE-sequences of 10 healthy knees were acquired before and immediately after loading (kneeling/squatting/heel sitting/knee bends). After cartilage segmentation, 3D-reconstruction and 3D-registration, colour-coded deformation maps were generated by voxel-based subtraction of loaded from unloaded datasets to visualize cartilage thickness changes in all knee compartments. Compression areas were found bifocal at the peripheral medial/caudolateral patella, both posterior femoral condyles and both anterior/central tibiae. Local cartilage thickening were found adjacent to the compression areas. Significant local strain ranged from +13 to -15 %. Changes were most pronounced after squatting, least after knee bends. Shape and location of deformation areas varied slightly with the loading paradigm, but followed a similar pattern consistent between different individuals. Voxel-based deformation maps identify individual in-vivo load-specific and posture-associated strain distribution in the articular cartilage. The data facilitate understanding individual knee loading properties and contribute to improve biomechanical 3 models. They lay a base to investigate the relationship between cartilage degeneration patterns in common osteoarthritis and areas at risk of cartilage wear due to mechanical loading in work-related activities. (orig.)

  17. Topographic deformation patterns of knee cartilage after exercises with high knee flexion: an in vivo 3D MRI study using voxel-based analysis at 3T

    Energy Technology Data Exchange (ETDEWEB)

    Horng, Annie; Stockinger, M.; Notohamiprodjo, M. [Ludwig-Maximilians-University Hospital Munich, Institute for Clinical Radiology, Munich (Germany); Raya, J.G. [New York University Langone Medical Center, Center for Biomedical Imaging, New York, NY (United States); Pietschmann, M. [Ludwig-Maximilians-University Hospital Munich, Department of Orthopedic Surgery, Munich (Germany); Hoehne-Hueckstaedt, U.; Glitsch, U.; Ellegast, R. [Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA), Sankt Augustin (Germany); Hering, K.G. [Miner' s Hospital, Department of Diagnostic Radiology, Dortmund (Germany); Glaser, C. [Ludwig-Maximilians-University Hospital Munich, Institute for Clinical Radiology, Munich (Germany); RZM Zentrum, Munich (Germany)

    2015-06-01

    To implement a novel voxel-based technique to identify statistically significant local cartilage deformation and analyze in-vivo topographic knee cartilage deformation patterns using a voxel-based thickness map approach for high-flexion postures. Sagittal 3T 3D-T1w-FLASH-WE-sequences of 10 healthy knees were acquired before and immediately after loading (kneeling/squatting/heel sitting/knee bends). After cartilage segmentation, 3D-reconstruction and 3D-registration, colour-coded deformation maps were generated by voxel-based subtraction of loaded from unloaded datasets to visualize cartilage thickness changes in all knee compartments. Compression areas were found bifocal at the peripheral medial/caudolateral patella, both posterior femoral condyles and both anterior/central tibiae. Local cartilage thickening were found adjacent to the compression areas. Significant local strain ranged from +13 to -15 %. Changes were most pronounced after squatting, least after knee bends. Shape and location of deformation areas varied slightly with the loading paradigm, but followed a similar pattern consistent between different individuals. Voxel-based deformation maps identify individual in-vivo load-specific and posture-associated strain distribution in the articular cartilage. The data facilitate understanding individual knee loading properties and contribute to improve biomechanical 3 models. They lay a base to investigate the relationship between cartilage degeneration patterns in common osteoarthritis and areas at risk of cartilage wear due to mechanical loading in work-related activities. (orig.)

  18. A capacitive DAC with custom 3-D 1-fF MOM unit capacitors optimized for fast-settling routing in high speed SAR ADCs

    International Nuclear Information System (INIS)

    Asynchronous successive approximation register (SAR) analog-to-digital converters (ADC) feature high energy efficiency but medium performance. From the point of view of speed, the key bottleneck is the unit capacitor size. In this paper, a small size three-dimensional (3-D) metal—oxide—metal (MOM) capacitor is proposed. The unit capacitor has a capacitance of 1-fF. It shapes as an umbrella, which is designed for fast settling consideration. A comparison among the proposed capacitor with other 3-D MOM capacitors is also given in the paper. To demonstrate the effectiveness of the MOM capacitor, a 6-b capacitive DAC is implemented in TSMC 1P9M 65 nm LP CMOS technology. The DAC consumes a power dissipation of 0.16 mW at the rate of 100 MS/s, excluding a source-follower based output buffer. Static measurement result shows that INL is less than ±1 LSB and DNL is less than ±0.5 LSB. In addition, a 100 MS/s 9-bit SAR ADC with the proposed 3-D capacitor is simulated. (paper)

  19. Electrochemical Behavior of Paraquat on a Highly Ordered Biosensor Based on an Unmodified DNA-3D Gold Nanoparticle Composite and Its Application

    International Nuclear Information System (INIS)

    Highlights: • Construction of unmodified DNA-3D gold nanoparticle composite was investigated. • Fabrication of hairpin DNA on GNPs was studied. • Redox mechanism of paraquat on the modified electrode was elucidated. • Determination method of paraquat on the modified electrode was established. - Abstract: DNA usually adsorbs gold nanoparticle by virtue of mercapto or amino group at one end of a DNA molecule. However, in this study, we report a highly ordered biosensor constructed using unmodified DNA molecules with consecutive adenines and three-dimensional gold nanoparticles (3D GNPs). The unmodified DNA-3D GNP composite was fabricated on gold electrodes and characterized through the use of scanning electron microscopy (SEM), atomic force microscopy (AFM), and electrochemical methods. Using an electrochemical quartz crystal microbalance (EQCM), the mechanism by which the unmodified DNA and GNPs combined was also studied. The modified electrode exhibited an ultrasensitive response to paraquat. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to study the linear relationships between the concentrations and the reduction peak currents. The linear relationship for DPV is 7.0 × 10−9 M to 1.5 × 10−6 M with a detection limit of 2.0 × 10−10 M. The redox mechanism of paraquat on this modified electrode was also elucidated. The feasibility of the proposed assay for use in human serum, human urine, and natural samples was investigated, and satisfactory results were obtained

  20. High-efficiency and wideband interlayer grating couplers in multilayer Si/SiO2/SiN platform for 3D integration of optical functionalities.

    Science.gov (United States)

    Sodagar, Majid; Pourabolghasem, Reza; Eftekhar, Ali A; Adibi, Ali

    2014-07-14

    We have designed interlayer grating couplers with single/double metallic reflectors for Si/SiO(2)/SiN multilayer material platform. Out-of-plane diffractive grating couplers separated by 1.6 μm thick buffer SiO(2) layer are vertically stacked against each other in Si and SiN layers. Geometrical optimization using genetic algorithm coupled with electromagnetic simulations using two-dimensional (2D) finite element method (FEM) results in coupler designs with high peak coupling efficiency of up to 89% for double- mirror and 64% for single-mirror structures at telecom wavelength. Also, 3-dB bandwidths of 40 nm and 50 nm are theoretically predicted for the two designs, respectively. We have fabricated the grating coupler structure with single mirror. Measured values for insertion loss and 3-dB bandwidth in the fabricated single-mirror coupler confirms the theoretical results. This opens up the possibility of low-loss 3D dense integration of optical functionalities in hybrid material platforms.