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Sample records for 35cl nucleus struktura

  1. Superdeformation and alpha - cluster structure in 35Cl

    CERN Document Server

    Bisoi, Abhijit; Sarkar, S; Ray, S; Basu, M Roy; Kanjilal, Debasmita; Nag, Somnath; Kumar, K Selva; Goswami, A; Madhavan, N; Muralithar, S; Bhowmik, R K

    2013-01-01

    A superdeformed (SD) band has been identified in a non - alpha - conjugate nucleus 35Cl. It crosses the negative parity ground band above 11/2- and becomes the yrast at 15/2-. Lifetimes of all relevant states have been measured to follow the evolution of collectivity. Enhanced B(E2), B(E1) values as well as energetics provide evidences for superdeformation and existence of parity doublet cluster structure in an odd-A nucleus for the first time in A = 40 region. Large scale shell model calculations assign (sd)16(pf)3 as the origin of these states. Calculated spectroscopic factors correlate the SD states in 35Cl to those in 36Ar.

  2. $^{35}$Cl+$^{12}$C asymmetrical fission excitation functions

    CERN Document Server

    Beck, C; Nouicer, R; Matsuse, T; Djerroud, B; Freeman, R M; Haas, F; Hachem, A; Morsad, A; Youlal, M; Sanders, S J; Dayras, R; Berthoumieux, E; Legrain, R; Pollacco, E C; Cavallaro, S; De Filippo, E; Lanzanò, G; Pagano, A; Sperduto, M L; Cavallaro, Sl

    1996-01-01

    The fully energy-damped yields from the ^{35}Cl+^{12}C reaction have been systematically investigated using particle-particle coincidence techniques at a ^{35}Cl bombarding energy of \\sim 8 MeV/nucleon. The fragment-fragment correlation data show that the majority of events arises from a binary-decay process with rather large numbers of secondary light-charged particles emitted from the two excited exit fragments. No evidence is observed for ternary break-up events. The binary-process results of the present measurement, along with those of earlier, inclusive experimental data obtained at several lower bombarding energies are compared with predictions of two different kinds of statistical model calculations. These calculations are performed using the transition-state formalism and the Extended Hauser-Feshbach method and are based on the available phase space at the saddle point and scission point of the compound nucleus, respectively. The methods give comparable predictions and are both in good agreement with ...

  3. 35Cl+12C asymmetrical fission excitation functions

    Science.gov (United States)

    Beck, C.; Mahboub, D.; Nouicer, R.; Matsuse, T.; Djerroud, B.; Freeman, R. M.; Haas, F.; Hachem, A.; Morsad, A.; Youlal, M.; Sanders, S. J.; Dayras, R.; Wieleczko, J. P.; Berthoumieux, E.; Legrain, R.; Pollacco, E.; Cavallaro, Sl.; de Filippo, E.; Lanzanó, G.; Pagano, A.; Sperduto, M. L.

    1996-07-01

    The fully energy-damped yields from the 35Cl+12C reaction have been systematically investigated using particle-particle coincidence techniques at a 35Cl bombarding energy of ~8 MeV/nucleon. The fragment-fragment correlation data show that the majority of events arises from a binary-decay process with rather large numbers of secondary light-charged particles emitted from the two excited exit fragments. No evidence is observed for ternary break-up events. The binary-process results of the present measurement, along with those of earlier, inclusive experimental data obtained at several lower bombarding energies are compared with predictions of two different kinds of statistical model calculations. These calculations are performed using the transition-state formalism and the extended Hauser-Feshbach method and are based on the available phase space at the saddle point and scission point of the compound nucleus, respectively. The methods give comparable predictions and are both in good agreement with the experimental results thus confirming the fusion-fission origin of the fully damped yields. The similarity of the predictions for the two models supports the claim that the scission point configuration is very close to that of the saddle point for the light 47V compound system. The results also give further support for the specific mass-asymmetry-dependent fission barriers needed in the transition-state calculation.

  4. {sup 35}Cl NQR in glassy crystal, 3-chlorothiophene

    Energy Technology Data Exchange (ETDEWEB)

    Fujimori, H., E-mail: fujimori@chs.nihon-u.ac.jp; Kaneko, T.; Asaji, T. [Nihon University, Department of Chemistry, College of Humanities and Sciences (Japan)

    2008-01-15

    {sup 35}Cl NQR measurements were carried out between 77 and 209 K for 3-chlorothiophene, which has a glass transition in a stable crystalline state. An NQR signal with full widths of about 100 kHz at half maximum was observed in this temperature range. The spin-lattice relaxation time T{sub 1} was measured at the peak frequencies. The activation energy {Delta}{epsilon}{sub a} obtained from the results of the T{sub 1} measurements showed a good agreement with those estimated from calorimetric measurements.

  5. Study of the Fusion-Fission Process in the $^{35}Cl + ^{24}Mg$ Reaction

    CERN Document Server

    Beck, C; Dayras, R; Cavallaro., Sl.

    1998-01-01

    Fusion-fission and fully energy-damped binary processes of the $^{35}$Cl+$^{24}$Mg reaction were investigated using particle-particle coincidence techniques at a $^{35}$Cl bombarding energy of E$_{lab}$ $\\approx$ 8 MeV/nucleon. Inclusive data were also taken in order to determine the partial wave distribution of the fusion process. The fragment-fragment correlation data show that the majority of events arises from a binary-decay process with a relatively large multiplicity of secondary light-charged particles emitted by the two primary excited fragments in the exit channel. No evidence is observed for ternary-breakup processes, as expected from the systematics recently established for incident energies below 15 MeV/nucleon and for a large number of reactions. The binary-process results are compared with predictions of statistical-model calculations. The calculations were performed using the Extended Hauser-Feshbach method, based on the available phase space at the scission point of the compound nucleus. This ...

  6. Fission fragment mass distributions in 35Cl+Sm,154144 reactions

    Science.gov (United States)

    Tripathi, R.; Sodaye, S.; Sudarshan, K.; Nayak, B. K.; Jhingan, A.; Pujari, P. K.; Mahata, K.; Santra, S.; Saxena, A.; Mirgule, E. T.; Thomas, R. G.

    2015-08-01

    Background: A new type of asymmetric fission was observed in β -delayed fission of 180Tl [Phys. Rev. Lett. 105, 252502 (2010), 10.1103/PhysRevLett.105.252502] as symmetric mass distribution would be expected based on conventional shell effects leading to the formation of N =50 fragments. Following this observation, theoretical calculations were carried out which predict asymmetric mass distribution for several mercury isotopes around mass region of ˜180 at low and moderate excitation energies [Moller, Randrup, and Sierk, Phys. Rev. C 85, 024306 (2012), 10.1103/PhysRevC.85.024306; Andreev, Adamian, and Antonenko, Phys. Rev. C 86, 044315 (2012), 10.1103/PhysRevC.86.044315]. Studies on fission fragment mass distribution are required in this mass region to investigate this newly observed phenomenon. Purpose: The fission fragment mass distributions have been measured in 35Cl+Sm,154144 reactions at Elab=152.5 ,156.1 ,and 163.7 MeV populating compound nuclei in the mass region of ˜180 with variable excitation energy and neutron number to investigate the nature of mass distribution. Method: The fission fragment mass distribution has been obtained by measuring the "time of flight (TOF)" of fragments with respect to the beam pulse using two multiwire proportional counters placed at θlab=±65 .5∘ with respect to the beam direction. From the TOF of fragments, their velocities were determined, which were used to obtain mass distribution taking the compound nucleus as the fissioning system. Results: For both systems, mass distributions, although, appear to be symmetric, could not be fitted well by a single Gaussian. The deviation from a single Gaussian fit is more pronounced for the 35Cl+144Sm reaction. A clear flat top mass distribution has been observed for the 35Cl+144Sm reaction at the lowest beam energy. The mass distribution is very similar to that observed in the 40Ca+142Nd reaction, which populated a similar compound nucleus, but for the pronounced dip in the

  7. Measuring 36Ar without H35Cl interference

    Science.gov (United States)

    Saxton, John

    2015-04-01

    Noble gas measurements are usually made in static mode, when the mass spectrometer sensitivity is inversely proportional to volume: this makes the building of very large instruments to obtain high mass resolution impracticable. A particularly challenging interference has hitherto been H35Cl, which differs in mass from 36Ar by 1 part in 3937. We have developed a method which makes improved use of the available MRP to remove interferences, and used it to obtain HCl-free 36Ar measurements on a multicollector instrument with MRP of only ~6000 (MRP= mass resolving power = m/dm 5-95% on side of peak). By arranging that the target mass position on a minor isotope (e.g. 36Ar), from which the interference must be removed, coincides with the ~50% point on the side of a major isotope (e.g. 40Ar), it is possible both to set the mass accurately and to verify the mass position and stability during measurements. The peak top of 40Ar is measured in a separate mass step. Two small corrections are necessary. One compensates for the residual HCl tail at the 36Ar position. The other arises because the peak is not totally flat in the region of interest: 40Ar and 36Ar+HCl are measured on the peak top, whilst 36Ar is measured at the extreme edge, with slightly lower efficiency. The required correction parameters can be obtained from a series of air calibrations with different target/interference ratios. With samples containing 4x10-15to 3x10-14moles of 40Ar, 36Ar/40Ar was measured, without HCl interference, to a 1σ precision of 0.5%, only slightly worse than counting statistics. This is potentially useful for 40Ar/39Ar dating, where 36Ar is used to correct for trapped air, and may be particularly significant for smaller or younger samples.

  8. First far-infrared high resolution analysis of the ν6 band of phosgene 35Cl2CO and 35Cl37ClCO

    Science.gov (United States)

    Flaud, J.-M.; Tchana, F. Kwabia; Lafferty, W. J.; Manceron, L.; Ndao, M.

    2016-08-01

    A Fourier transform spectrum of phosgene (Cl2CO) has been recorded in the 22.5 μm spectral region at a resolution of 0.00102 cm-1 using a Bruker IFS125HR spectrometer coupled to synchrotron radiation leading to the observation of the ν6 vibrational bands of the two isotopologues 35Cl2CO and 35Cl37ClCO. The corresponding upper state ro-vibrational levels were fit using Watson-type Hamiltonians. In this way it was possible to reproduce the upper state ro-vibrational levels to within the experimental uncertainty i.e. ∼0.30 × 10-3 cm-1. Very accurate rotational and centrifugal distortion constants were derived from the fit together with the following band centers: ν0(ν6,35Cl2CO) = 443.172062(15) cm-1, ν0(ν6,35Cl37ClCO) = 440.534956(17) cm-1.

  9. Dependence of (35)Cl NQR on hydrogen bonding and temperature in dichlorophenol-aniline charge transfer complexes.

    Science.gov (United States)

    Ramananda, D; Ramesh, K P; Uchil, J

    2007-10-01

    The hydrogen-bonded charge transfer complexes of aniline with pi-acceptors (or proton donors) such as 2,5-, 2,6-, 3,4- and 3,5-dichlorophenol were prepared. The (35)Cl nuclear quadrupole resonance (NQR) frequencies of these charge transfer complexes in the temperature range 77-300 K were measured to ascertain the existence or otherwise of a phase transition upon complex formation. Further, the NQR frequency and asymmetry parameter of the electric field gradient at the site of quadrupole nucleus were used to estimate the chemical bond parameters, namely ionic bond, double bond character of the carbon-chlorine(C--Cl) bond and the percentage charge transfer between the donor-acceptor components in charge transfer complexes. The effect of hydrogen bonding and temperature on the charge transfer process is analysed.

  10. Magnetic dipole interaction and line widths in NQR: 35Cl NQR spectrum of chloroform

    Science.gov (United States)

    Subramanian, V. Harihara; Narasimhan, P. T.

    35 Cl NQR spectra of CHC1 3 and CDCl 3 have been recorded at 77 K with an injection and phase-locked NQR spectrometer. The theoretical 35Cl NQR spectrum of CHC1 3 has been computed with the inclusion of H-C1 intramolecular magnetic dipole Interaction In the quadrupole Hamiltonian. It has been possible to obtain the H-C1 internuclear distance in the CHC1 3 molecule by assuming that contributions to 35Cl NQR line width from static electric effects and relaxation effects are the same in CHC1 3 and CDCl 3 and that the magnetic dipole interaction contribution to 35Cl NQR line width in CDCl 3 is negligible. The calculated H-C1 distance values are: 2.34 Å for the 'a' site and 2.49 Å for the 'b' site. These values may be compared with the x-ray value of 2.31 Å. It has also been possible to assign the observed NQR frequencies to the appropriate chlorine sites in the unit cell.

  11. High spin structure of {sup 35}Cl and the sd-fp shell gap

    Energy Technology Data Exchange (ETDEWEB)

    Kshetri, Ritesh [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Saha Sarkar, M. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India)]. E-mail: maitrayee.sahasarkar@saha.ac.in; Ray, Indrani [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Banerjee, P. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Sarkar, S. [Department of Physics, Bengal Engineering and Science University, Shibpur, Howrah 711103 (India); Raut, Rajarshi [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Goswami, A. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Chatterjee, J.M. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Chattopadhyay, S. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Datta Pramanik, U. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Mukherjee, A. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Dey, C.C. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Bhattacharya, S. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Dasmahapatra, B. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700064 (India); Bhowal, Samit [Department of Physics, Surendranath Evening College, Kolkata 700009 (India); Gangopadhyay, G. [University of Calcutta, 92, Acharya Prafulla Chandra Road, Kolkata 700009 (India); Datta, P. [Anandamohan College, 102/1, Raja Rammohan Sarani, Kolkata 700009 (India); Jain, H.C. [Tata Institute of Fundamental Research, Mumbai 400005 (India); Bhowmik, R.K. [Inter-University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India); Muralithar, S.; Singh, R.P.; Kumar, R. [Inter-University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India)

    2007-01-15

    The high spin states of {sup 35}Cl have been studied by in-beam {gamma}-spectroscopy following the fusion-evaporation reaction {sup 12}C({sup 28}Si,{alpha}p){sup 35}Cl at E{sub lab}=70 and 88 MeV, using the Indian National Gamma (Clover) Array (INGA). Lifetimes of six new excited states have been estimated for the first time. To understand the underlying structure of the levels and transition mechanisms, experimental results have been compared with those from the large basis cross-shell shell model calculations. Involvement of orbitals from fp shell and squeezing of the sd-fp shell gap seem to be essential for reliable reproduction of high spin states.

  12. 35Cl profiling using centric scan SPRITE with variable flip angle excitation

    Science.gov (United States)

    Romanenko, Konstantin V.; Cano-Barrita, P. F. de J.; Balcom, Bruce J.

    2009-05-01

    An efficient MRI technique for quantitative density profiling of samples with fast spin-lattice relaxation ( T1 technique. Strong excitation of the sample at the k-space origin improves the sensitivity with respect to the original centric scan SPRITE technique. Radio frequency pulse durations are defined so as to provide uniform excitation of the sample at every k-space point. For a particular k-space point the pulse duration is required to be less than the inverse sample bandwidth. Simulations permit one to examine distortions from ideal profile geometry due to flip angle and spin-lattice relaxation effects. The proposed technique is especially suitable for the observation of low sensitivity samples, in particular, low-γ nuclei like 35Cl. In some cases, this strategy permits one to reduce the number of scans, i.e. the experiment time, by a factor of 100, depending on hardware, sample length and tolerable resolution loss. The designed pulse scheme is tested on cylindrical agar gel and type 1 Portland cement paste phantoms prepared to provide 1H and 35Cl signals, respectively.

  13. Zeeman study of 35Cl NQR in tetrachlorocyclopentene-1,3-dione

    Science.gov (United States)

    Mano, K.; Sengupta, S.; Giezendanner, D.; Lucken, E. A. C.

    1983-01-01

    The 35Cl NQR Zeeman spectrum in a single crystal of tetrachlorocyclopentene-1,3-dione has been studied for the two lines, 38734.1 (H) and 35667.0 (L) KHz at 21°C by a pulsed FT NQR spectrometer equipped for automatic measurements. Each line yields 12 efgt's in a magnetic field. Their directional symmetry (three two-fold and four three-fold axes) indicates that the crystal system is cubic. This is confirmed by its X-ray powder pattern and inspection with the polarization microscope; space group Fd3 or Fm3, a = 21.910 Å, Z = 48, D c = 1.78, D o = 1.75 . The molecular structure and the molecular orientations in the unit cell are determined from the results. The η-values are 5.8 and 21.6% for H and L, respectively.

  14. Anomalous H/D isotope effect on {sup 35}Cl NQR frequencies in piperidinium p-chlorobenzoate

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, Ryo; Honda, Hisashi, E-mail: hhonda@yokohama-cu.ac.jp [Yokohama City University, Graduate School of Integrated Science (Japan); Kimura, Taiki [Yokohama City University, Faculty of Science (Japan); Nakata, Eiichi; Takamizawa, Satoshi; Noro, Sumiko [Yokohama City University, Graduate School of Integrated Science (Japan); Ishimaru, Shin' ichi [Tokyo Denki University, Department of Green and Sustainable Chemistry (Japan)

    2008-01-15

    Anomalous isotope effects were detected in the {sup 35}Cl nuclear quadrupole resonance (NQR) frequency of piperidinium p-chlrobenzoate (C{sub 5}H{sub 10}NH. ClC{sub 6}H{sub 4}COOH) by deuteration of hydrogen atoms. The atoms were determined to form two kinds of N-H...O type H-bonds in the crystal structure. Large frequency shifts of the {sup 35}Cl resonance lines reaching 288 kHz at 77 K and 278 kHz at room temperature were caused upon deuteration, in spite of the fact that the Cl atoms in the molecule do not form hydrogen bonds in the crystal. Results of single crystal X-ray diffraction measurements and density-functional-theorem calculations suggest that a dihedral-angle change of 1.8{sup o} between benzene and the piperidine ring contributes to {sup 35}Cl NQR anomalous frequency shifts.

  15. {sup 35}Cl NQR spectra of group 1 and silver dichloromethanesulfonates

    Energy Technology Data Exchange (ETDEWEB)

    Gillette, Gabriel; Wulfsberg, Gary, E-mail: gwulfsbe@mtsu.edu [Middle Tennessee State University, Department of Chemistry (United States)

    2008-01-15

    The dichloromethanesulfonates of silver and other +1-charged cations, M{sup +} (Cl{sub 2}CHSO{sub 3}{sup -}) (M = Ag, Tl, Li, Na, K, Rb, Cs) were synthesized and studied by {sup 35}Cl NQR. Dichloromethanesulfonic acid was prepared by the methanolysis of dichloromethanesulfonyl chloride, and was then neutralized with the carbonates of the +1-charged cations to produce the corresponding dichloromethanesulfonate salt. This NQR study completed the investigation of the chloroacetates and chloromethanesulfonates of silver, Ag{sup +} (Cl{sub x}CH{sub 3-x}SO{sub 3}{sup -}) and Ag{sup +}(Cl{sub x}CH{sub 3-x}CO{sub 2}{sup -}), and suggests (1) that the ability of organochlorine atoms to coordinate to silver decreases as the number of electron-withdrawing groups (Cl, SO{sub 3}{sup -}, CO{sub 2}{sup -}) attached to the carbon atom increases; (2) that the unusually large NQR spectral width found among M{sup +} (Cl{sub 2}CHCO{sub 2}{sup +}) salts is not present among M{sup +} (Cl{sub 2}CHSO{sub 3}{sup +}) salts, and therefore is not generally characteristic of the dichloromethyl group in salts.

  16. 35Cl NQR zeeman study of perchloro-bicyclopentadienyl by a pulsed FT nor spectrometer

    Science.gov (United States)

    Mano, K.; Sengupta, S.; Litzistorf, G.; Lucken, E. A. C.

    1983-12-01

    Zeeman measurements were performed on 35Cl NQR lines in a single crystal of perchloro-bicyclopentadienyl at room temperature by a pulsed FT NQR system. The compound gives ten NQR lines : ν 1 = 36347.6, ν 2 = 36361.2, ν 3 = 36634.2, ν 4 = 36684.8, ν 5 = 36715.5, ν 6 = 37008.0, ν 7 = 37194.4, ν 8 = 37266.9, ν 9 = 38871.1, and ν 0 = 39323.8(kHz) at 291.5 K. Each line yields two electric field gradients (efgt's) in a magnetic field. The asymmetry parameters (η) of ν 1, ν 2, ν 3, ν 4, ν 5, ν 6, ν 7, ν 8, ν 9 and ν 0 are 14.1, 14.0, 14.2, 13.9, 14.5, 9.6, 10.3, 12.1, 4.2 and 4.8%, respectively. From the relative orientations between the principal axes of the efgt's, the molecular structure has been deduced. The molecule has a cisoid conformation rotated by 51 o from the pure s-cis form. The rotation angle agrees well with the value calculated using Urey-Bradley force field constants.

  17. 35Cl NQR Zeeman study of perchloro-2-cyclopentenone by a pulsed FT NQR spectrometer

    Science.gov (United States)

    Mano, K.; Sengupta, S.; Lucken, E. A. C.; Litzistorf, G.

    Zeeman measurements have been performed on the 35Cl NQR lines of a single crystal of perchloro-2-cyclopentenone at room temperature using a pulsed FT NQR system. The compound exhibits six NQR lines, ν(1) = 36 589.4, ν(2) = 37 383.7, ν(3) = 38 631.7, ν(4) = 38 812.0, ν(5) = 39 429.7 and ν(6) = 39 750.0, at 288 K. Each line yields two electric field gradient tensors in a magnetic field. The asymmetry parameters (η) of ν(1), ν(2), ν(3), ν(4), ν(5) and ν(6) are 18.3, 12.8, 1.9, 0.8, 4.9 and 5.6%, respectively. From the relative orientations of the principal axes of the field gradient tensors, the molecular structure has been deduced. The five-membered ring is puckered by ca. 30°. The η values and the nature of the bonding are discussed in connection with the molecular structure.

  18. Analysis of temperature dependence of {sup 35}Cl-NQR frequency in 2,4-D herbicide (2,4-dichlorophenoxy acetic acid); Analiza temperaturowej zaleznosci czestosci {sup 35}Cl-NQR w herbicydzie 2,4-D (kwas dichlorofenoksyoctowy)

    Energy Technology Data Exchange (ETDEWEB)

    Mazurek, P.; Ostafin, M.; Kasprzak, J.; Nogaj, B. [Inst. Fizyki, Uniwersytet A. Mickiewicza, Poznan (Poland)

    1994-12-31

    Biological activity of herbicide depends on electronic structure and molecule dynamics. The former parameter has been investigated by means of NQR spectra on {sup 35}Cl nuclei of 2,4-dichlorophenoxy acetic acid. The analysis of temperature dependency of observed frequency has been done. 12 refs, 3 figs, 1 tab.

  19. Struktura i svojstva plazma sprej Aps - Nikal - Aluminid prevlake

    Directory of Open Access Journals (Sweden)

    Mihailo Rade Mrdak

    2013-06-01

    temperaturi pri brzini od 1 mm/min. Mikrostrukturna analiza slojeva prevlaka urađena je na svetlosnom mikroskopu. Morfologija površine deponovane prevlake i morfologija loma najboljih slojeva ispitana je na SEM-u (skening elektronskom mikroskopu. Rezultati i diskusija Vrednosti mikrotvrdoće slojeva prevlaka u direktnoj su vezi sa plazma sprej odstojanjem. Plazma sprej odstojanja bitno utiču na vrednosti mikrotvrdoće i čvrstoće spoja deponovanih slojeva. Slojevi Ni20Al prevlake deponovane sa najmanjim odstojanjem od 80 mm imaju vrednost mikrotvrdoće od  220HV0.3 koja je u granicama koju propisuje proizvođač praha (190–230HV0.3 (Material Product Data Sheet, 2011. Najveću vrednost mikrotvrdoće od 273 HV0.3 imali su slojevi sa najvećim udelom oksida koji su deponovani sa plazma sprej odstojanjem od 100 mm. Slojevi prevlaka deponovanih sa većim odstojanjem imali su vrednosti mikrotvrdoće iznad propisanih vrednosti. Vrednosti mikrotvrdoća prevlaka bile su u skladu sa udelima oksida u deponovanim slojevima. Merenjem vrednosti zatezne čvrstoće spoja ustanovljeno je da su se za sva tri plazma sprej odstojanja dobile vrednosti više od 20.7MPa, koju propisuje proizvođač praha (Material Product Data Sheet, 2011. Sve deponovane prevlake imale su dobre vrednosti zatezne čvrstoće spoja koje proizilaze iz egzotermne reakcije Al i Ni koja se dešava za vreme depozicije praha (McPherson, Cheang, 1989, (Deevi, et al., 1997, pp.335-344, (Material Product Data Sheet, 2011. Najveću vrednost čvrstoće spoja od 39MPa pokazali su slojevi koji su deponovani sa najmanjim plazma sprej odstojanjem. Ti slojevi imali su najmanji udeo oksida NiO i Υ- Al2O3 i pora. Na slikama 3 i 4. su prikazane mikrostrukture slojeva deponovanih sa plazma sprej odstojanjem 80 mm, koji su imali najbolju mikrostrukturu i mehaničke karakteristike. Struktura prevlake je lamelarna. Slojevi prevlake deponovani su kontinualno bez prisustva mikropukotina i makropukotina. U slojevima nisu prisutne

  20. Single crystal zeeman effect studies on 35Cl NQR lines of 2,6-dichlorophenol

    Science.gov (United States)

    Prasad, N. V. L. N.; Venkatacharyulu, P.; Premaswarup, D.

    1987-10-01

    Zeeman effect studies on the two 35Cl NQR lines in cylindrical single crystals of 2,6-dichlorophenol were carried out using a self-quenched super-regenerative NQR spectrometer to obtain information on the nature of the crystalline unit cell and the effect of hydrogen bonding on the electric field gradient tensor. Analysis of the experimental data reveals: (1) the results are in good agreement with those reported from X-ray studies; (2) the crystal is unequivocally identified as belonging to the orthorhombic system; (3) there are two crystallographically equivalent and four physically nonequivalent directions for the principal field gradients for both the low and high frequency resonance lines; (4) the directions of the crystalline a, b, c axes are uniquely identified as (90°, 0°), (0°, -), and (90°, 90°); (5) the b-axis is identified as the growth axis; (6) there are a minimum of four molecules per unit cell, the four molecules lie in different planes, which are, however, connected by symmetry operations; (7)_there exists a weak intramolecular hydrogen bonding in the crystal; (8) the asymmetry parameters for the loci corresponding to the low frequency resonance line, which is affected by hydrogen bonding, are less than the asymmetry parameters of the loci corresponding to the high frequency resonance line, which is not affected by hydrogen bonding; (9) the single bond and ionic bond characters for the hish frequency line are less than that of the low frequency line, while the double bond character for the low frequency line is less than that of the high frequency line and (10) the small deviation between the single bond and double bond characters of the two resonance lines is attributed to the existence of weak hydrogen bonding in the crystal.

  1. Electronic structure and biological activity of chosen DDT-type insecticides studied by 35Cl-NQR.

    Science.gov (United States)

    Jadzyn, Maciej; Nogaj, Bolesław

    2009-02-01

    A correlation between the electronic structure and biological activity of chosen dichlorodiphenyltrichloroethane (DDT)-type insecticides: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane, 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane, 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene, 2,2-bis(4-chlorophenyl)ethanoic acid and 4,4'-dichlorobenzophenone (used in agriculture) has been analysed on the basis of the (35)Cl-nuclear quadrupole resonance (NQR) spectroscopy. The (35)Cl-NQR resonance frequencies measured at 77 K have been correlated with the lethal dose (LD(50)) parameter that characterises the biological activity of these insecticides.

  2. Formation of a necklike structure in 35Cl+12C and 197Au reactions at 43 MeV/nucleon

    Science.gov (United States)

    Larochelle, Y.; Gingras, L.; Beaulieu, L.; Qian, X.; Saddiki, Z.; Djerroud, B.; Doré, D.; Laforest, R.; Roy, R.; Samri, M.; St-Pierre, C.; Ball, G. C.; Bowman, D. R.; Galindo-Uribarri, A.; Hagberg, E.; Horn, D.; López, J. A.; Robinson, T.

    1997-04-01

    The experimental signature of the formation of a necklike structure, with a velocity between that of the projectilelike emitter and that of the targetlike emitter, is investigated with the same beam and experimental setup for targets lighter and heavier than the projectile. The reactions are 35Cl on 12C and on 197Au at 43 MeV/nucleon. Particle velocity distributions are compared with two-source statistical simulations and the presence of a necklike structure is inferred from the data. In the second part of the paper, dynamical model simulations with the formation of a necklike structure are presented for the 35Cl+12C system at 43 MeV/nucleon.

  3. First measurement of the 34S(p ,γ )35Cl reaction rate through indirect methods for presolar nova grains

    Science.gov (United States)

    Gillespie, S. A.; Parikh, A.; Barton, C. J.; Faestermann, T.; José, J.; Hertenberger, R.; Wirth, H.-F.; de Séréville, N.; Riley, J. E.; Williams, M.

    2017-08-01

    Sulphur isotopic ratio measurements may help to establish the astrophysical sites in which certain presolar grains were formed. Nova model predictions of the 34S/32S ratio are, however, unreliable due to the lack of an experimental 34S(p ,γ )35Cl reaction rate. To this end, we have measured the 34S(3He,d )35Cl reaction at 20 MeV using a high resolution quadrupole-dipole-dipole-dipole magnetic spectrograph. Twenty-two levels over 6.2 MeV transfer spectroscopic factors have been measured for the first time over the energy range relevant for novae. With this new spectroscopic information a new 34S(p ,γ )35Cl reaction rate has been determined using a Monte Carlo method. Hydrodynamic nova model calculations have been performed using this new reaction rate. These models show that remaining uncertainties in the 34S(p ,γ ) rate affect nucleosynthesis predictions by less than a factor of 1.4, and predict a 34S/32S isotopic ratio of 0.014-0.017. Since recent type II supernova models predict 34S/32S=0.026 -0.053 , the 34S/32S isotopic ratio may be used, in conjunction with other isotopic signatures, to distinguish presolar grains from oxygen-neon nova and type II supernova origin. Our results address a key nuclear physics uncertainty on which recent considerations discounting the nova origin of several grains depend.

  4. The 35Cl/37Cl isotopic ratio in dense molecular clouds: HIFI observations of hydrogen chloride towards W3A

    CERN Document Server

    Cernicharo, J; Daniel, F; Agundez, M; Caux, E; de Graauw, T; De Jonge, A; Kester, D; Leduc, H G; Steinmetz, E; Stutzki, J; Ward, J S

    2010-01-01

    We report on the detection with the HIFI instrument on board the Herschel satellite of the two hydrogen chloride isotopologues, H35Cl and H37Cl, towards the massive star-forming region W3A. The J=1-0 line of both species was observed with receiver 1b of the HIFI instrument at 625.9 and 624.9 GHz. The different hyperfine components were resolved. The observations were modeled with a non-local, non-LTE radiative transfer model that includes hyperfine line overlap and radiative pumping by dust. Both effects are found to play an important role in the emerging intensity from the different hyperfine components. The inferred H35Cl column density (a few times 1e14 cm^-2), and fractional abundance relative to H nuclei (~7.5e^-10), supports an upper limit to the gas phase chlorine depletion of ~200. Our best-fit model estimate of the H35Cl/H37Cl abundance ratio is ~2.1+/-0.5, slightly lower, but still compatible with the solar isotopic abundance ratio (~3.1). Since both species were observed simultaneously, this is the...

  5. 35Cl NQR spectra of phosphorus chlorides and their molecular conformations in crystals. Part 1. Phosphorus (III) chlorides RPCl 2

    Science.gov (United States)

    Kozlov, E. S.; Kapustin, E. G.; Soifer, G. B.

    2000-09-01

    For the phosphorus chlorides RPCl 2 (R=Cl, Me, ClCH 2, CF 3, Et, i-Pr, Me 2C=CH, PhCH=CH, Me 2N, Et 2N, Pr 2N, MeO, PhO) and R'PCl 2 (R'=Ar, 2-thienyl) two linear correlations between the 35Cl NQR frequencies and charges on the chlorine atoms of the PCl 2 groups calculated by the MNDO procedure have been found. It was shown that the 35Cl NQR spectra and the relative magnitudes of the charges on the chlorine atoms of the PCl 2 groups can be used to determine conformation of the RPCl 2 molecules in crystal. Ab initio (RHF/6-31 G ∗ and MP2/6-31 G ∗) calculations showed that the gauche conformation of Me 2NPCl 2 molecule is more stable than trans conformation. In light of ab initio calculations electron diffraction results (Vilkov L.V., Khaikin L.S., Dokl. Akad. Nauk SSSR, 168 (1966) 810) are erroneous. The NBO analysis confirmed the presence of donor-acceptor interactions between the lone pair orbital of the nitrogen atom and the antibonding orbitals of the P-Cl bonds.

  6. Studies of the electronic structure and biological activity of chosen 1,4-benzodiazepines by {sup 35}Cl NQR spectroscopy and DFT calculations

    Energy Technology Data Exchange (ETDEWEB)

    Bronisz, K. [Department of Physics, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan (Poland); Ostafin, M. [Department of Physics, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan (Poland)], E-mail: ostifnqr@amu.edu.pl; Poleshchuk, O. Kh. [Department of Chemistry, Tomsk Pedagogical University, Komsomolskii 75, 634041 Tomsk (Russian Federation); Mielcarek, J. [Faculty of Pharmacy, University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan (Poland); Nogaj, B. [Department of Physics, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan (Poland)

    2006-11-08

    Selected derivatives of 1,4-benzodiazepine: lorazepam, lormetazepam, oxazepam and temazepam, used as active substances in anxiolytic drugs, have been studied by {sup 35}Cl NQR method in order to find the correlation between electronic structure and biological activity. The {sup 35}Cl NQR resonance frequencies ({nu} {sub Q}) measured at 77 K have been correlated with the following parameters characterising their biological activity: biological half-life period (t {sub 0.5}), affinity to benzodiazepine receptor (IC{sub 50}) and mean dose equivalent. The results of experimental study of some benzodiazepine derivatives by nuclear quadrupole resonance of {sup 35}Cl nuclei are compared with theoretical results based on DFT calculations which were carried out by means of Gaussian'98 W software.

  7. Studies of the electronic structure and biological activity of chosen 1,4-benzodiazepines by 35Cl NQR spectroscopy and DFT calculations

    Science.gov (United States)

    Bronisz, K.; Ostafin, M.; Poleshchuk, O. Kh.; Mielcarek, J.; Nogaj, B.

    2006-11-01

    Selected derivatives of 1,4-benzodiazepine: lorazepam, lormetazepam, oxazepam and temazepam, used as active substances in anxiolytic drugs, have been studied by 35Cl NQR method in order to find the correlation between electronic structure and biological activity. The 35Cl NQR resonance frequencies ( νQ) measured at 77 K have been correlated with the following parameters characterising their biological activity: biological half-life period ( t0.5), affinity to benzodiazepine receptor (IC 50) and mean dose equivalent. The results of experimental study of some benzodiazepine derivatives by nuclear quadrupole resonance of 35Cl nuclei are compared with theoretical results based on DFT calculations which were carried out by means of Gaussian'98 W software.

  8. Faktorska struktura, psihometrijske karakteristike i kritična vrijednost hrvatskoga prijevoda CORE-OM upitnika

    Directory of Open Access Journals (Sweden)

    Natasa Jokić-Begić

    2014-07-01

    Full Text Available Upitnik za ispitivanje općih psihopatoloških teškoća CORE-OM (engl. Clinical Outcomes in Routine Evaluation – Outcome Measure ljestvica je osmišljena kao panteorijska i pandijagnostička mjera opće psihičke uznemirenosti koja se upotrebljava na svim razinama psihološke skrbi, od trijaže do praćenja psihoterapijskih učinaka.Cilj je ovoga istraživanja provjeriti metrijske karakteristike hrvatskoga prijevoda CORE-OM upitnika na općem uzorku odraslih građana Republike Hrvatske te utvrditi diskriminativne sposobnosti utvrđivanjem kritičnoga graničnog rezultata.U istraživanju je sudjelovalo ukupno N=608 sudionika podijeljenih u dvije skupine, neklinička (n=425 i klinička skupina (n=183. Osim CORE-OM upitnika primijenjeni su Beckov upitnik depresivnosti – II te Upitnik anksioznosti kao stanja i osobine ličnosti.Utvrđena je četverofaktorska struktura s jednim g-faktorom koja odgovara originalnoj strukturi i koja sugerira da se ovim upitnikom mjeri stupanj opće psihičke uznemirenosti, pri čemu je moguće utvrditi u kojim je područjima ona posebno izražena. Potvrđena je zadovoljavajuća unutrašnja konzistencija i test-retest pouzdanost, te dobra konvergentna valjanost. Na temelju je provedenih ROC analiza određen kritični rezultat od 1.38, koji je isti za muškarce i žene i na temelju kojeg je moguće prepoznavanje osoba s izraženim psihičkim smetnjama.CORE-OM kliničarima može poslužiti za procjenu opće uznemirenosti te biti smjernica za daljnji psihodijagnostički postupak, a istraživačima kao pouzdana i valjana mjera prisutnosti i intenziteta psihopatoloških smetnji.

  9. (37)Cl/(35)Cl isotope ratio analysis in perchlorate by ion chromatography/multi collector -ICPMS: Analytical performance and implication for biodegradation studies.

    Science.gov (United States)

    Zakon, Yevgeni; Ronen, Zeev; Halicz, Ludwik; Gelman, Faina

    2017-10-01

    In the present study we propose a new analytical method for (37)Cl/(35)Cl analysis in perchlorate by Ion Chromatography(IC) coupled to Multicollector Inductively Coupled Plasma Mass Spectrometry (MC-ICPMS). The accuracy of the analytical method was validated by analysis of international perchlorate standard materials USGS-37 and USGS -38; analytical precision better than ±0.4‰ was achieved. (37)Cl/(35)Cl isotope ratio analysis in perchlorate during laboratory biodegradation experiment with microbial cultures enriched from the contaminated soil in Israel resulted in isotope enrichment factor ε(37)Cl = -13.3 ± 1‰, which falls in the range reported previously for perchlorate biodegradation by pure microbial cultures. The proposed analytical method may significantly simplify the procedure for isotope analysis of perchlorate which is currently applied in environmental studies. Copyright © 2017. Published by Elsevier Ltd.

  10. Correlation between proton transfer and (35)Cl NQR frequency as well as molecular geometry of chloranilic acid in co-crystals with some organic bases.

    Science.gov (United States)

    Asaji, Tetsuo; Seliger, Janez; Zagar, Veselko; Ishida, Hiroyuki

    2010-07-01

    Proton transfer in hydrogen-bonded organic co-crystals of chloranilic acid with some organic bases was investigated by nuclear quadrupole resonance (NQR) spectroscopy. The (35)Cl NQR frequencies of chloranilic acid molecule as well as (14)N NQR frequencies of the organic base molecule were measured with the conventional pulse methods as well as double-resonance methods, respectively. The extent of proton transfer in the O...H...N hydrogen bond was estimated from Townes-Dailey analysis of the (14)N NQR parameters. The (35)Cl NQR frequency and molecular geometry of chloranilic acid are correlated to the extent of proton transfer in the protonation process of the organic base molecule. It is shown that the hydrogen bond affects the pi-electron system of chloranilic acid. Geometry dependence of the O...H...N hydrogen bond, i.e. the H-N valence bond order versus the hydrogen-bond geometry correlation is also discussed.

  11. Formation of a necklike structure in {sup 35}Cl+{sup 12}C and {sup 197}Au reactions at 43 MeV/nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Larochelle, Y.; Gingras, L.; Beaulieu, L.; Qian, X.; Saddiki, Z.; Djerroud, B.; Dore, D.; Laforest, R.; Roy, R.; Samri, M.; St-Pierre, C. [Laboratoire de Physique Nucleaire, Departement de Physique, Universite Laval, Quebec, G1K 7P4 (CANADA); Ball, G.C.; Bowman, D.R.; Galindo-Uribarri, A.; Hagberg, E.; Horn, D. [AECL, Chalk River Laboratories, Ontario, K0J 1J0 (CANADA); Lopez, J.A.; Robinson, T. [Department of Physics, University of Texas at El Paso, El Paso, Texas 79968-0515 (United States)

    1997-04-01

    The experimental signature of the formation of a necklike structure, with a velocity between that of the projectilelike emitter and that of the targetlike emitter, is investigated with the same beam and experimental setup for targets lighter and heavier than the projectile. The reactions are {sup 35}Cl on {sup 12}C and on {sup 197}Au at 43 MeV/nucleon. Particle velocity distributions are compared with two-source statistical simulations and the presence of a necklike structure is inferred from the data. In the second part of the paper, dynamical model simulations with the formation of a necklike structure are presented for the {sup 35}Cl+{sup 12}C system at 43 MeV/nucleon. {copyright} {ital 1997} {ital The American Physical Society}

  12. Detection of chloronium and measurement of the 35Cl/37Cl isotopic ratio at z=0.89 toward PKS1830-211

    CERN Document Server

    Muller, S; Guelin, M; Henkel, C; Combes, F; Gerin, M; Aalto, S; Beelen, A; Darling, J; Horellou, C; Martin, S; Menten, K M; Dinh-V-Trung,; Zwaan, M A

    2014-01-01

    We report the first extragalactic detection of chloronium (H2Cl+), in the z=0.89 absorber in front of the lensed blazar PKS1830-211. The ion is detected through its 1_11-0_00 line along two independent lines of sight toward the North-East and South-West images of the blazar. The relative abundance of H2Cl+ is significantly higher (by a factor ~7) in the NE line of sight, which has a lower H2/H fraction, indicating that H2Cl+ preferably traces the diffuse gas component. From the ratio of the H2^35Cl+ and H2^37Cl+ absorptions toward the SW image, we measure a 35Cl/37Cl isotopic ratio of 3.1 (-0.2; +0.3) at z=0.89, similar to that observed in the Galaxy and the solar system.

  13. The C-Cl bonds in trichloroethylidene trichlorolactic ester, Cl3CCHOCOCHOCCl3. A 35Cl-NQR single crystal study

    Science.gov (United States)

    Hashimoto, M.; Nagarajan, V.; Weiden, Norbert; Weiss, Alarich

    1983-01-01

    By single crystal 35Cl-NQR with a 4π Zeeman spectrometer, the six independent 35Cl-nuclear quadrupole coupling tensors in trichloroethylidene trichlorolactic ester (chloralide) Cl3CCHOCOCHOCC13 have been studied at T=21 °C. The directions of the electric field gradient (EFG) tensor components have been determined. The main axes φzz are within ±0.5° parallel to the C-Cl bound directions. Very small asymmetry parameters in the range 0.005≤η≤0.053 are characteristic for the EFG tensors of Cl bond to carbon in aliphatic systems, and the six nuclear quadrupole coupling constants are found in the range 76.053≤e2qQh-1/MHz≤78.790. The orientations of the principal axes φxx and φyy is explained as due to intramolecular interactions likely of through space origin.

  14. A study of transition-metal organometallic complexes combining 35Cl solid-state NMR spectroscopy and 35Cl NQR spectroscopy and first-principles DFT calculations.

    Science.gov (United States)

    Johnston, Karen E; O'Keefe, Christopher A; Gauvin, Régis M; Trébosc, Julien; Delevoye, Laurent; Amoureux, Jean-Paul; Popoff, Nicolas; Taoufik, Mostafa; Oudatchin, Konstantin; Schurko, Robert W

    2013-09-09

    A series of transition-metal organometallic complexes with commonly occurring metal-chlorine bonding motifs were characterized using (35)Cl solid-state NMR (SSNMR) spectroscopy, (35)Cl nuclear quadrupole resonance (NQR) spectroscopy, and first-principles density functional theory (DFT) calculations of NMR interaction tensors. Static (35)Cl ultra-wideline NMR spectra were acquired in a piecewise manner at standard (9.4 T) and high (21.1 T) magnetic field strengths using the WURST-QCPMG pulse sequence. The (35)Cl electric field gradient (EFG) and chemical shielding (CS) tensor parameters were readily extracted from analytical simulations of the spectra; in particular, the quadrupolar parameters are shown to be very sensitive to structural differences, and can easily differentiate between chlorine atoms in bridging and terminal bonding environments. (35)Cl NQR spectra were acquired for many of the complexes, which aided in resolving structurally similar, yet crystallographically distinct and magnetically inequivalent chlorine sites, and with the interpretation and assignment of (35)Cl SSNMR spectra. (35)Cl EFG tensors obtained from first-principles DFT calculations are consistently in good agreement with experiment, highlighting the importance of using a combined approach of theoretical and experimental methods for structural characterization. Finally, a preliminary example of a (35)Cl SSNMR spectrum of a transition-metal species (TiCl4) diluted and supported on non-porous silica is presented. The combination of (35)Cl SSNMR and (35)Cl NQR spectroscopy and DFT calculations is shown to be a promising and simple methodology for the characterization of all manner of chlorine-containing transition-metal complexes, in pure, impure bulk and supported forms.

  15. 35Cl NQR study of lattice dynamic and magnetic property of a crystalline coordination polymer {CuCA(phz)(H 2O) 2} n

    Science.gov (United States)

    Gotoh, Kazuma; Terao, Takeshi; Asaji, Tetsuo

    2007-01-01

    Copper(II) compounds {CuCA(phz)(H 2O) 2} n (H 2CA = chloranilic acid, phz = phenazine) having a layer structure of -CuCA(H 2O) 2- polymer chains and phenazine were studied by 35Cl nuclear quadrupole resonance (NQR). The single NQR line observed at 35.635 MHz at 261.5 K increased to 35.918 MHz at 4.2 K. The degree of reduction of electric field gradient due to lattice vibrations was similar to that of chloranilic acid crystal. Temperature dependence of spin-lattice relaxation time, T1, of the 35Cl NQR signal below 20 K, between 20 and 210 K, and above 210 K, was explained by (1) a decrease of effective electron-spin density caused by antiferromagnetic interaction, (2) a magnetic interaction between Cl nuclear-spin and electron-spins on paramagnetic Cu(II) ions, and (3) an increasing contribution from reorientation of ligand molecules, respectively. The electron spin-exchange parameter ∣ J∣ between the neighboring Cu(II) electrons was estimated to be 0.33 cm -1 from the T1 value of the range 20-210 K. Comparing this value with that of J = -1.84 cm -1 estimated from the magnetic susceptibility, it is suggested that the magnetic dipolar coupling with the electron spins on Cu(II) ions must be the principal mechanism for the 35Cl NQR spin-lattice relaxation of {CuCA(phz)(H 2O) 2} n but a delocalization of electron spin over the chloranilate ligand has to be taken into account.

  16. NMR shielding and spin–rotation constants of {sup 175}LuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br, {sup 127}I) molecules

    Energy Technology Data Exchange (ETDEWEB)

    Demissie, Taye B. [Centre for Theoretical and Computational Chemistry Department of Chemistry, UiT – The Arctic University of Norway, N-9037 Tromsø (Norway)

    2015-12-31

    This presentation demonstrates the relativistic effects on the spin-rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants and shielding spans of {sup 175}LuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br, {sup 127}I) molecules. The results are obtained from calculations performed using density functional theory (non-relativistic and four-component relativistic) and coupled-cluster calculations. The spin-rotation constants are compared with available experimental values. In most of the molecules studied, relativistic effects make an order of magnitude difference on the NMR absolute shielding constants.

  17. Heavy-ion fusion cross sections and barrier distributions for {sup 12}C, {sup 16}O, {sup 28}Si and {sup 35}Cl on {sup 92}Zr

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P. [P G Department of Physics and Research Centre, Payyanur College, Payyanur-670327 (India)], E-mail: drkpsanthosh@gmail.com; Bobby Jose, V. [P G Department of Physics and Research Centre, Payyanur College, Payyanur-670327 (India); Joseph, Antony; Varier, K.M. [Department of Physics, University of Calicut, Calicut-673635 (India)

    2009-02-01

    The fusion excitation functions and barrier distributions for the fusion of {sup 12}C, {sup 16}O, {sup 28}Si and {sup 35}Cl on {sup 92}Zr have been calculated using one-dimensional barrier penetration model, taking scattering potential as the sum of Coulomb and proximity potential. Calculated results are compared with experimental data and CC calculations using code CCFULL. At and above the barrier the computed cross sections match well with the experimental data, whereas below the barrier, calculations with nuclear surface tension coefficient improved by Reisdorf in the proximity potential give good fit. Reduced reaction cross sections for the systems have also been described.

  18. Protonic motion in one-dimensional hydrogen-bonded molecular crystal [4,6-dmpH][Hca] as revealed by {sup 35}Cl NQR

    Energy Technology Data Exchange (ETDEWEB)

    Asaji, Tetsuo, E-mail: asaji@chs.nihon-u.ac.jp [Department of Chemistry, College of Humanities and Sciences, Nihon University, Sakurajosui 3-25-40, Setagaya-ku, Tokyo 156-8550 (Japan); Konnai, Akiko [Navigation and System Engineering Department, National Maritime Research Institute, Shinkawa 6-38-1, Mitaka, Tokyo 181-0004 (Japan); Oguni, Masaharu [Department of Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, O-okayama 2-12-1, Meguro-ku, Tokyo 152-8551 (Japan)

    2012-03-20

    Highlights: Black-Right-Pointing-Pointer 1-D ferroelectric hydrogen-bonded chain. Black-Right-Pointing-Pointer The migration of a protonic soliton in the chain. Black-Right-Pointing-Pointer Protonic motion was detected by {sup 35}Cl NQR spin-lattice relaxation measurements. Black-Right-Pointing-Pointer Heat capacity revealed no phase transition in [4,6-dmpH][Hca]. - Abstract: A protonic motion in the 1-D hydrogen-bonded zigzag chain in 4,6-dimethylpyrimidinium hydrogen chloranilate, [4,6-dmpH][Hca], was studied from the measurements of {sup 35}Cl nuclear quadrupole resonance (NQR) spin-lattice relaxation time (T{sub 1}). The four NQR frequencies were observed at 36.846, 36.767, 35.945, and 35.905 MHz at 77 K. The temperature dependences of these frequencies were smooth and continuous in 77-360 K. The absence of solid-solid phase transition and the metastable phase was confirmed by heat capacity measurements. Temperature dependence of the NQR T{sub 1} suggests an excitation of a motion above ca. 200 K with the activation energy of 11.5 kJ mol{sup -1}. In the stable phase too, the excitation of proton transfer is expected to occur as suggested for the metastable phase of as-grown crystals. Such transfer motion may be possible at the kink structure of the 1-D ferroelectric zigzag chain, and the kink can migrate in the chain accordingly.

  19. A measurement of parity-violating gamma-ray asymmetries in polarized cold neutron capture on 35Cl, 113Cd, and 139La

    CERN Document Server

    Mitchell, G S; Bowman, J D; Chupp, T E; Coulter, K P; Gericke, M T W; Jones, G L; Leuschner, M B; Nann, H; Page, S A; Penttila, S I; Smith, T B; Snow, W M; Wilburn, W S

    2004-01-01

    An apparatus for measuring parity-violating asymmetries in gamma-ray emission following polarized cold neutron capture was constructed as a 1/10th scale test of the design for the forthcoming n+p->d+gamma experiment at LANSCE. The elements of the polarized neutron beam, including a polarized 3He neutron spin filter and a radio frequency neutron spin rotator, are described. Using CsI(Tl) detectors and photodiode current mode readout, measurements were made of asymmetries in gamma-ray emission following neutron capture on 35Cl, 113Cd, and 139La targets. Upper limits on the parity-allowed asymmetry $s_n \\cdot (k_{\\gamma} \\times k_n)$ were set at the level of 7 x 10^-6 for all three targets. Parity-violating asymmetries $s_n \\cdot k_{\\gamma}$ were observed in 35Cl, A_gamma = (-29.1 +- 6.7) x 10^-6, and 139La, A_gamma = (-15.5 +- 7.1) x 10^-6, values consistent with previous measurements.

  20. Temperature variation of ultralow frequency modes and mean square displacements in solid lasamide (diuretic drug) studied by 35Cl-NQR, X-ray and DFT/QTAIM.

    Science.gov (United States)

    Latosińska, Jolanta Natalia; Latosińska, Magdalena; Kasprzak, Jerzy; Tomczak, Magdalena; Maurin, Jan Krzysztof

    2012-10-25

    The application of combined (35)Cl-NQR/X-ray/DFT/QTAIM methods to study the temperature variation of anisotropic displacement parameters and ultralow frequency modes of anharmonic torsional vibrations in the solid state is illustrated on the example of 2,4-dichloro-5-sulfamolybenzoic acid (lasamide, DSBA) which is a diuretic and an intermediate in the synthesis of furosemide and thus its common impurity. The crystallographic structure of lasamide is solved by X-ray diffraction and refined to a final R-factor of 3.06% at room temperature. Lasamide is found to crystallize in the triclinic space group P-1, with two equivalent molecules in the unit cell a = 7.5984(3) Å, b = 8.3158(3) Å, c = 8.6892(3) Å; α = 81.212(3)°, β = 73.799(3)°, γ = 67.599(3)°. Its molecules form symmetric dimers linked by two short and linear intermolecular hydrogen bonds O-H···O (O-H···O = 2.648 Å and ∠OHO = 171.5°), which are further linked by weaker and longer intermolecular hydrogen bonds N-H···O (N-H···O = 2.965 Å and ∠NHO = 166.4°). Two (35)Cl-NQR resonance frequencies, 36.899 and 37.129 MHz, revealed at room temperature are assigned to chlorine sites at the ortho and para positions, relative to the carboxyl functional group, respectively. The difference in C-Cl(1) and C-Cl(2) bond lengths only slightly affects the value of (35)Cl-NQR frequencies, which results mainly from chemical inequivalence of chlorine atoms but also involvement in different intermolecular interactions pattern. The smooth decrease in both (35)Cl-NQR frequencies with increasing temperature in the range of 77-300 K testifies to the averaging of EFG tensor at each chlorine site due to anharmonic torsional vibrations. Lasamide is thermally stable; no temperature-induced release of chlorine or decomposition of this compound is detected. The temperature dependence of ultralow frequency modes of anharmonic small-angle internal torsional vibrations averaging EFG tensor and mean square angle

  1. Temperature- and pressure-dependent study of 35Cl NQR frequency and spin lattice relaxation time in 2,3-dichloroanisole.

    Science.gov (United States)

    Ramu, L; Ramesh, K P; Ramananda, D; Chandramani, R

    2010-08-01

    The temperature and pressure dependence of (35)Cl NQR frequency and spin lattice relaxation time (T(1)) were investigated in 2,3-dichloroanisole. Two NQR signals were observed throughout the temperature and pressure range studied. T(1) were measured in the temperature range from 77 to 300 K and from atmospheric pressure to 5 kbar. Relaxation was found to be due to the torsional motion of the molecule and also reorientation of motion of the CH(3) group. T(1) versus temperature data were analyzed on the basis of Woessner and Gutowsky model, and the activation energy for the reorientation of the CH(3) group was estimated. The temperature dependence of the average torsional lifetimes of the molecules and the transition probabilities were also obtained. NQR frequency shows a nonlinear behavior with pressure, indicating both dynamic and static effects of pressure. The pressure coefficients were observed to be positive for both the lines. A thermodynamic analysis of the data was carried out to determine the constant volume temperature coefficients of the NQR frequency. The variation of spin lattice time with pressure was very small, showing that the relaxation is mainly due to the torsional motions of the molecules.

  2. 35Cl NQR frequency and spin lattice relaxation time in 3,4-dichlorophenol as a function of pressure and temperature.

    Science.gov (United States)

    Ramu, L; Ramesh, K P; Chandramani, R

    2013-01-01

    The pressure dependences of (35)Cl nuclear quadrupole resonance (NQR) frequency, temperature and pressure variation of spin lattice relaxation time (T(1)) were investigated in 3,4-dichlorophenol. T(1) was measured in the temperature range 77-300 K. Furthermore, the NQR frequency and T(1) for these compounds were measured as a function of pressure up to 5 kbar at 300 K. The temperature dependence of the average torsional lifetimes of the molecules and the transition probabilities W(1) and W(2) for the Δm = ±1 and Δm = ±2 transitions were also obtained. A nonlinear variation of NQR frequency with pressure has been observed and the pressure coefficients were observed to be positive. A thermodynamic analysis of the data was carried out to determine the constant volume temperature coefficients of the NQR frequency. An attempt is made to compare the torsional frequencies evaluated from NQR data with those obtained by IR spectra. On selecting the appropriate mode from IR spectra, a good agreement with torsional frequency obtained from NQR data is observed. The previously mentioned approach is a good illustration of the supplementary nature of the data from IR studies, in relation to NQR studies of compounds in solid state.

  3. Determination of molecular stopping cross section of 12C, 16O, 28Si, 35Cl, 58Ni, 79Br, and 127I in silicon nitride

    Science.gov (United States)

    Barradas, N. P.; Bergmaier, A.; Mizohata, K.; Msimanga, M.; Räisänen, J.; Sajavaara, T.; Simon, A.

    2015-10-01

    Silicon nitride is a technologically important material in a range of applications due to a combination of important properties. Ion beam analysis techniques, and in particular, heavy ion elastic recoil detection analysis can be used to determine the stoichiometry of silicon nitride films, which often deviates from the ideal Si3N4, as well as the content of impurities such as hydrogen, even in the presence of other materials or in a matrix containing heavier elements. Accurate quantification of IBA results depends on the basic data used in the data analysis. Quantitative depth profiling relies on the knowledge of the stopping power cross sections of the materials studied for the ions involved, which in the case of HI-ERDA is both the primary beam, and the recoiled species. We measured the stopping cross section of 12C, 16O, 28Si, 35Cl, 58Ni, 79Br, and 127I in a well-characterised silicon nitride membrane. The measurements were made by independent groups utilising different experimental setups and methods. In some cases there is extensive overlap of the energy range in different experiments, allowing a comparison of the different results. The four independent data sets reported in this work are in excellent agreement with each other, in the cases where similar energy ranges were measured. On the other hand, the data are in most cases higher than calculations made with the interpolative schemes SRIM and MSTAR together with the Bragg rule. Better agreement is found with MSTAR in some of the cases studied. This work is a significant extension of the heavy ion stopping power data base for silicon nitride.

  4. Spatial distribution of damage products of /sup 84/Kr ions (1 MeV/amu) and /sup 35/Cl ions (1 MeV/amu) in cellulose triacetate

    Energy Technology Data Exchange (ETDEWEB)

    Moliton, J.P. (Universite de Limoges, France); Boutinaud, C.; Decossas, J.L.; Vareille, J.C.; Teyssier, J.L.; Delaunay, B.

    1982-07-01

    The authors' earlier results on ..gamma..- and heavy-ion-radiation damage in cellulose triacetate (CTA) are compared with those of previous authors on uv- and ..gamma..-radiation damage in the same material. Thus the common effects of these different methods of irradiation can be distinguished from those characteristic of the radiation employed. With heavy-ion radiation the production of stable radicals is accompanied by C-O cleavage. In the case of /sup 84/Kr (1 MeV/amu) ions, the number of free radicals produced is investigated, without distinguishing the species, by using the scavenger technique in the solid phase, combined with uv spectroscopy. On the other hand, C-O cleavage is observed by ir spectroscopy, with its inherent selectivity. A statistical study shows that the experimental curves representative of the evolution of the optical transmittance ratio before and after irradiation L(N) versus the ion fluence N are of exponential type: L(N) = ..cap alpha..e/sup ..beta..N/ where ..beta.. is a parameter related to the volume damaged by a single ion and, therefore, to the latent track size. The latter is approximated by a cylinder whose height is equal to the range of the ion. For /sup 84/Kr/sup 8 +/ (1.1 MeV/amu) the track length is 21 ..mu... For each type, damages are localized within a radius of 250 A for free-radical yields, 148 A for cellulosic chain cleavages, 108 A for deacetylation, and 100 A for opening of pyrannosic rings. The track length is 14 ..mu.. for /sup 35/Cl/sup 6 +/ (1 MeV/amu), while the radius of the cylinder in which free radicals are produced is only 80 A.

  5. Herschel observations of interstellar chloronium. II - Detections toward G29.96-0.02, W49N, W51, and W3(OH), and determinations of the ortho-to-para and $^{35}$Cl/$^{37}$Cl isotopic ratios

    CERN Document Server

    Neufeld, David A; Gerin, Maryvonne; Goicoechea, Javier R; Goldsmith, Paul F; Gry, Cecile; Gupta, Harshal; Herbst, Eric; Indriolo, Nick; Lis, Dariusz; Menten, Karl M; Monje, Raquel; Mookerjea, Bhaswati; Persson, Carina; Sonnentrucker, Paule; Wolfire, Mark G

    2015-01-01

    We report additional detections of the chloronium molecular ion, H$_2$Cl$^+$, toward four bright submillimeter continuum sources: G29.96, W49N, W51, and W3(OH). With the use of the HIFI instrument on the Herschel Space Observatory, we observed the $2_{12}-1_{01}$ transition of ortho-H$_2^{35}$Cl$^+$ at 781.627 GHz in absorption toward all four sources. Much of the detected absorption arises in diffuse foreground clouds that are unassociated with the background continuum sources and in which our best estimates of the $N({\\rm H_2Cl^+})/N({\\rm H})$ ratio lie in the range $(0.9 - 4.8) \\times 10^{-9}$. These chloronium abundances relative to atomic hydrogen can exceed the predictions of current astrochemical models by up to a factor of 5. Toward W49N, we have also detected the $2_{12}-1_{01}$ transition of ortho-H$_2^{37}$Cl$^+$ at 780.053 GHz and the $1_{11}-0_{00}$ transition of para-H$_2^{35}$Cl$^+$ at 485.418 GHz. These observations imply $\\rm H_2^{35}Cl^+/H_2^{37}Cl^+$ column density ratios that are consisten...

  6. Struktura Fibonaccijevih kock: pregled

    OpenAIRE

    Klavžar, Sandi

    2015-01-01

    The Fibonacci cube ▫$Gamma_n$▫ is the subgraph of the ▫$n$▫-cube induced by the binary strings that contain no two consecutive 1s. These graphs are applicable as interconnection networks and in theoretical chemistry, and lead to the Fibonacci dimension of a graph. In this paper, a survey on Fibonacci cubes is given with an emphasis on their structure, including representations, recursive construction, hamiltonicity, degree sequence and other enumeration results. Their median nature that leads...

  7. Conformations and intermolecular interactions pattern in solid chloroxylenol and triclosan (API of anti-infective agents and drugs). A (35)Cl NQR, (1)H-(14)N NQDR, X-ray and DFT/QTAIM study.

    Science.gov (United States)

    Latosińska, J N; Latosińska, M; Tomczak, M A; Seliger, J; Zagar, V; Maurin, J K

    2012-02-01

    Two antibacterial and antifungal agents, chloroxylenol (4-chloro-3,5-dimethyl-phenol) and triclosan (5-chloro-2-(2',4'-dichlorophenoxy)-phenol), were studied experimentally in solid state with an X-ray, (35)Cl-nuclear quadrupole resonance (NQR) and (17)O-nuclear quadrupole double resonance (NQDR) spectroscopies and, theoretically, with the density functional theory/quantum theory of atoms in molecules (DFT/QTAIM). The crystallographic structure of triclosan, which crystallises in space group P31 with one molecule in the asymmetric unit [a = 12.64100(10), b = 12.64100(10), c = 6.71630(10) Å], was solved with an X-ray and refined to a final R-factor of 2.81% at room temperature. The NQR frequencies of (35)Cl and (17)O were detected with the help of the density functional theory (DFT) assigned to particular chlorine and oxygen sites in the molecules of both compounds. The NQR frequencies at (35)Cl sites in chloroxylenol and triclosan were found to be more differentiated than frequencies at the (17)O site. The former better describes the substituent withdrawing effects connected to π-electron delocalization within the benzene rings and the influence of temperature; whereas, those at the (17)O site provide more information on O-H bond and intermolecular interactions pattern. The conformation adopted by diphenyl ether of triclosan in solid state was found to be typical of diphenyl ethers, but the opposite to those adopted when it was bound to different inhibitors. According to an X-ray study, temperature had no effect on the conformation of the diphenyl ring of triclosan, which was the same at 90 K and at room temperature (RT). The scattering of NQR frequencies reproduced by the DFT under assumption of the X-ray data at 90 K and RT is found to be a good indicator of the quality of resolution of the crystallographic structure.

  8. BFKL Pomeron calculus: Nucleus-nucleus scattering

    Energy Technology Data Exchange (ETDEWEB)

    Contreras, Carlos, E-mail: carlos.contreras@usm.cl [Departamento de Fisica, Universidad Tecnica Federico Santa Maria, Avda. Espana 1680, and Centro Cientifico-Tecnologico de Valparaiso, Casilla 110-V, Valparaiso (Chile); Levin, Eugene, E-mail: leving@post.tau.ac.il [Departamento de Fisica, Universidad Tecnica Federico Santa Maria, Avda. Espana 1680, and Centro Cientifico-Tecnologico de Valparaiso, Casilla 110-V, Valparaiso (Chile); Department of Particle Physics, School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978 (Israel); Miller, Jeremy S., E-mail: jeremy.miller@ist.utl.pt [Department of Particle Physics, School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978 (Israel); CENTRA, Departamento de Fisica, Instituto Superior Tecnico (IST), Av. Rovisco Pais, 1049-001 Lisboa (Portugal)

    2012-04-15

    In this paper the action of the BFKL Pomeron calculus is rewritten in momentum representation, and the equations of motion for nucleus-nucleus collisions are derived, in this representation. We found the semiclassical solutions to these equations, outside of the saturation domain. Inside this domain these equations reduce to the set of delay differential equations, and their asymptotic solutions are derived.

  9. Development of ΔE-E telescope ERDA with 40 MeV 35Cl7+ beam at MALT in the University of Tokyo optimized for analysis of metal oxynitride thin films

    Science.gov (United States)

    Harayama, I.; Nagashima, K.; Hirose, Y.; Matsuzaki, H.; Sekiba, D.

    2016-10-01

    We have developed a compact ΔE-E telescope elastic recoil detection analysis (ERDA) system, for the first time at Micro Analysis Laboratory, Tandem Accelerator (MALT) in the University of Tokyo, which consists of a gas ionization chamber and solid state detector (SSD) for the quantitative analysis of light elements. The gas ionization chamber is designed to identify the recoils of O and N from metal oxynitrides thin films irradiated with 40 MeV 35Cl7+. The length of the electrodes along the beam direction is 50 mm optimized to sufficiently separate energy loss of O and N recoils in P10 gas at 6.0 × 103 Pa. The performance of the gas ionization chamber was examined by comparing the ERDA results on the SrTaO2N thin films with semi-empirical simulation and the chemical compositions previously determined by nuclear reaction analysis (NRA) and Rutherford backscattering spectrometry (RBS). We also confirmed availability of the gas ionization chamber for identifying not only the recoils of O and N but also those of lithium, carbon and fluorine.

  10. Absolute NMR shielding scales and nuclear spin-rotation constants in (175)LuX and (197)AuX (X = (19)F, (35)Cl, (79)Br and (127)I).

    Science.gov (United States)

    Demissie, Taye B; Jaszuński, Michał; Komorovsky, Stanislav; Repisky, Michal; Ruud, Kenneth

    2015-10-28

    We present nuclear spin-rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants, and shielding spans of all the nuclei in (175)LuX and (197)AuX (X = (19)F, (35)Cl, (79)Br, (127)I), calculated using coupled-cluster singles-and-doubles with a perturbative triples (CCSD(T)) correction theory, four-component relativistic density functional theory (relativistic DFT), and non-relativistic DFT. The total nuclear spin-rotation constants determined by adding the relativistic corrections obtained from DFT calculations to the CCSD(T) values are in general in agreement with available experimental data, indicating that the computational approach followed in this study allows us to predict reliable results for the unknown spin-rotation constants in these molecules. The total NMR absolute shielding constants are determined for all the nuclei following the same approach as that applied for the nuclear spin-rotation constants. In most of the molecules, relativistic effects significantly change the computed shielding constants, demonstrating that straightforward application of the non-relativistic formula relating the electronic contribution to the nuclear spin-rotation constants and the paramagnetic contribution to the shielding constants does not yield correct results. We also analyze the origin of the unusually large absolute shielding constant and its relativistic correction of gold in AuF compared to the other gold monohalides.

  11. Absolute NMR shielding scales and nuclear spin–rotation constants in {sup 175}LuX and {sup 197}AuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br and {sup 127}I)

    Energy Technology Data Exchange (ETDEWEB)

    Demissie, Taye B., E-mail: taye.b.demissie@uit.no; Komorovsky, Stanislav; Repisky, Michal; Ruud, Kenneth [Centre for Theoretical and Computational Chemistry, Department of Chemistry, UiT The Arctic University of Norway, N-9037 Tromsø (Norway); Jaszuński, Michał [Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44, 01 224 Warszawa (Poland)

    2015-10-28

    We present nuclear spin–rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants, and shielding spans of all the nuclei in {sup 175}LuX and {sup 197}AuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br, {sup 127}I), calculated using coupled-cluster singles-and-doubles with a perturbative triples (CCSD(T)) correction theory, four-component relativistic density functional theory (relativistic DFT), and non-relativistic DFT. The total nuclear spin–rotation constants determined by adding the relativistic corrections obtained from DFT calculations to the CCSD(T) values are in general in agreement with available experimental data, indicating that the computational approach followed in this study allows us to predict reliable results for the unknown spin–rotation constants in these molecules. The total NMR absolute shielding constants are determined for all the nuclei following the same approach as that applied for the nuclear spin–rotation constants. In most of the molecules, relativistic effects significantly change the computed shielding constants, demonstrating that straightforward application of the non-relativistic formula relating the electronic contribution to the nuclear spin–rotation constants and the paramagnetic contribution to the shielding constants does not yield correct results. We also analyze the origin of the unusually large absolute shielding constant and its relativistic correction of gold in AuF compared to the other gold monohalides.

  12. Absolute NMR shielding scales and nuclear spin-rotation constants in 175LuX and 197AuX (X = 19F, 35Cl, 79Br and 127I)

    Science.gov (United States)

    Demissie, Taye B.; Jaszuński, Michał; Komorovsky, Stanislav; Repisky, Michal; Ruud, Kenneth

    2015-10-01

    We present nuclear spin-rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants, and shielding spans of all the nuclei in 175LuX and 197AuX (X = 19F, 35Cl, 79Br, 127I), calculated using coupled-cluster singles-and-doubles with a perturbative triples (CCSD(T)) correction theory, four-component relativistic density functional theory (relativistic DFT), and non-relativistic DFT. The total nuclear spin-rotation constants determined by adding the relativistic corrections obtained from DFT calculations to the CCSD(T) values are in general in agreement with available experimental data, indicating that the computational approach followed in this study allows us to predict reliable results for the unknown spin-rotation constants in these molecules. The total NMR absolute shielding constants are determined for all the nuclei following the same approach as that applied for the nuclear spin-rotation constants. In most of the molecules, relativistic effects significantly change the computed shielding constants, demonstrating that straightforward application of the non-relativistic formula relating the electronic contribution to the nuclear spin-rotation constants and the paramagnetic contribution to the shielding constants does not yield correct results. We also analyze the origin of the unusually large absolute shielding constant and its relativistic correction of gold in AuF compared to the other gold monohalides.

  13. Onuf's nucleus X

    DEFF Research Database (Denmark)

    Schrøder, H D

    1981-01-01

    in the length of the nucleus was observed. Based on the cytoarchitecture the nucleus could be divided in three parts, a cranial, a dorsomedial and a ventrolateral. All parts of the nucleus consisted of chromatin-rich medium-sized neurons, and apparent direct appositions between different cells bodies as well......The first, second and third sacral segments of 59 human spinal cords were examined in order to localize and describe Onuf's nucleus X. The nucleus was found to be situated in the ventral horn of the segments S2 and S3; only in very few spinal cords did it extend into S1. A significant variation...... as between cell bodies and large dendrites were observed. Characteristic findings in the neuropil surrounding the nucleus were the sparsity of myelinated fibers and the presence of dendritic bundles. The present observations are compared to the descriptions of a morphologically similar nucleus...

  14. Determination of molecular stopping cross section of {sup 12}C, {sup 16}O, {sup 28}Si, {sup 35}Cl, {sup 58}Ni, {sup 79}Br, and {sup 127}I in silicon nitride

    Energy Technology Data Exchange (ETDEWEB)

    Barradas, N.P., E-mail: nunoni@ctn.ist.utl.pt [Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Unversidade de Lisboa, Estrada Nacional 10 ao km 139.7, 2695-066 Bobadela LRS (Portugal); Bergmaier, A. [Institut für Angewandte Physik und Messtechnik, Fakultät für Luft und Raumfahrttechnik, Werner-Heisenberg-Weg 39, D-85577 Neubiberg (Germany); Mizohata, K. [Department of Physics, University of Helsinki, P.O. Box 43, FI-00014 University of Helsinki (Finland); Msimanga, M. [iThemba LABS Gauteng, National Research Foundation, Private Bag 11, WITS 2050, Johannesburg (South Africa); Department of Physics, Tshwane University of Technology, Private Bag X680, Pretoria 0001 (South Africa); Räisänen, J. [Department of Physics, University of Helsinki, P.O. Box 43, FI-00014 University of Helsinki (Finland); Sajavaara, T. [Department of Physics, University of Jyväskylä, Survontie 9, 40014 Jyväskylä (Finland); Simon, A. [International Atomic Energy Agency, Division of Physical and Chemical Sciences, Vienna International Centre, P.O. Box 100, A-1400 Vienna (Austria); Institute of Nuclear Research of the Hungarian Academy of Sciences, (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary)

    2015-10-01

    Silicon nitride is a technologically important material in a range of applications due to a combination of important properties. Ion beam analysis techniques, and in particular, heavy ion elastic recoil detection analysis can be used to determine the stoichiometry of silicon nitride films, which often deviates from the ideal Si{sub 3}N{sub 4}, as well as the content of impurities such as hydrogen, even in the presence of other materials or in a matrix containing heavier elements. Accurate quantification of IBA results depends on the basic data used in the data analysis. Quantitative depth profiling relies on the knowledge of the stopping power cross sections of the materials studied for the ions involved, which in the case of HI-ERDA is both the primary beam, and the recoiled species. We measured the stopping cross section of {sup 12}C, {sup 16}O, {sup 28}Si, {sup 35}Cl, {sup 58}Ni, {sup 79}Br, and {sup 127}I in a well-characterised silicon nitride membrane. The measurements were made by independent groups utilising different experimental setups and methods. In some cases there is extensive overlap of the energy range in different experiments, allowing a comparison of the different results. The four independent data sets reported in this work are in excellent agreement with each other, in the cases where similar energy ranges were measured. On the other hand, the data are in most cases higher than calculations made with the interpolative schemes SRIM and MSTAR together with the Bragg rule. Better agreement is found with MSTAR in some of the cases studied. This work is a significant extension of the heavy ion stopping power data base for silicon nitride.

  15. STRUKTURA KOGNITIVNIH SPOSOBNOSTI PERSPEKTIVNIH BOKSERA

    Directory of Open Access Journals (Sweden)

    Benin Murić

    2011-09-01

    Full Text Available All psychosomatic characteristics and abilities are very important for achieving sportingsuccess in boxing. Therefore, it is the obligation of professionals to seek out, among other things, new methods that permit the identification of personality dimensions andtheir connections, which are responsible for achieving success in sport. We analyzed the structure of boxers’ cognitive abilities. The research’s mission is to determine the structure of boxers’ cognitive abilities. The study is managed with the hypothesis: H1-In the space of cognitive abilities it is expected to obtain a general factor. The population from which the sample was taken for this study can be defined as a population of boxers from boxing clubs in Serbia aged 15-19 years. Our sample of 100 boxers, boxing club members from Serbia, was optimal for the planned research. Basic cognitive processes can be reduced to perceptual functions, parallel and serial processes, which are probably controlled by a central processor responsible for coordinating all cognitive functions.

  16. In beam {gamma}-ray spectroscopy of the odd-odd nucleus {sup 144}Tb

    Energy Technology Data Exchange (ETDEWEB)

    Sferrazza, M. [Padua Univ. (Italy). Dipt. di Fisica]|[Istituto Nazionale di Fisica Nucleare, Padua (Italy)]|[Cambridge Univ. (United Kingdom). Cavendish Lab.; Cardona, M.A. [Istituto Nazionale di Fisica Nucleare, Legnaro (Italy). Lab. Nazionali di Legnaro; Bazzacco, D. [Padua Univ. (Italy). Dipt. di Fisica]|[Istituto Nazionale di Fisica Nucleare, Padua (Italy); Lunardi, S. [Padua Univ. (Italy). Dipt. di Fisica]|[Istituto Nazionale di Fisica Nucleare, Padua (Italy); Maglione, E. [Padua Univ. (Italy). Dipt. di Fisica]|[Istituto Nazionale di Fisica Nucleare, Padua (Italy); De Angelis, G. [Istituto Nazionale di Fisica Nucleare, Legnaro (Italy). Lab. Nazionali di Legnaro

    1996-03-01

    The level scheme of the N=79 nucleus {sup 144}Tb was investigated via in beam {gamma}-ray spectroscopy using the {sup 112}Sn({sup 35}Cl,n2p), {sup 116}Sn({sup 32}S,3np) and {sup 89}Y({sup 58}Ni,2np) reactions. States up to I{approx}20 and E{sub x}{approx}5 MeV were established above the 6{sup -} {beta}{sup +} decaying isomer. Two new isomers with half-life of 0.67(6) {mu}s and 2.8(3) {mu}s were identified. The level scheme of {sup 144}Tb is interpreted in the framework of the spherical shell model with a few valence nucleons outside the {sup 146}Gd core. (orig.)

  17. Nucleus Driven Electronic Pulsation

    CERN Document Server

    Ludwig, H; Xue, S -S

    2014-01-01

    We derive and solve by the spectral method the equations for a neutral system of ultra-relativistic electrons that are compressed to the radius of the nucleus and subject to a driving force. This driving force can be thought of as originating from a nuclear breathing mode, a possibility we discuss in detail.

  18. Neutrino nucleus cross sections

    CERN Document Server

    Athar, M Sajjad; Singh, S K; Vacas, M J Vicente

    2008-01-01

    We present the results of our calculation which has been performed to study the nuclear effects in the quasielastic, inelastic and deep inelastic scattering of neutrinos(antineutrinos) from nuclear targets. These calculations are done in the local density approximation. We take into account the effect of Pauli blocking, Fermi motion, Coulomb effect, renormalization of weak transition strengths in the nuclear medium in the case of the quasielastic reaction. The inelastic reaction leading to production of pions is calculated in a $\\Delta $- dominance model taking into account the renormalization of $\\Delta$ properties in the nuclear medium and the final state interaction effects of the outgoing pions with the residual nucleus. We discuss the nuclear effects in the $F_{3}^{A}(x)$ structure function in the deep inelastic neutrino(antineutrino) reaction using a relativistic framework to describe the nucleon spectral function in the nucleus.

  19. Heavy flavor in nucleus-nucleus and proton-nucleus: quenching, flow and correlations

    CERN Document Server

    Nardi, M; De Pace, A; Monteno, M; Prino, F

    2015-01-01

    We present recent results for heavy-flavor observables in nucleus-nucleus collisions at LHC energies, obtained with the POWLANG transport setup. The initial creation of c-cbar and b-bbar pairs is simulated with a perturbative QCD approach (POWHEG+PYTHIA); their propagation in the medium (created in the nucleus-nucleus or in proton-nucleus collision) is studied with the relativistic Langevin equation, here solved using weak-coupling transport coefficients. Successively, the heavy quarks hadronize in the medium. We compute the nuclear modification factor and the elliptic flow parameter of the final D mesons both in nucleus-nucleus and in (for the first time, in the POWLANG setup) proton-nucleus collisions and compare our results to experimental data.

  20. Nucleus-nucleus potential with shell-correction contribution

    CERN Document Server

    Denisov, V Yu

    2015-01-01

    The full relaxed-density potential between spherical nuclei is considered as a sum of the macroscopic and shell-correction contributions. The macroscopic part of the potential is related to a nucleus-nucleus potential obtained in the framework of the extended Thomas-Fermi approach with the Skyrme and Coulomb forces and the relaxed-density ansatz for evaluation of proton and neutron densities of interacting nuclei. A simple prescription for the shell-correction part of the total potential is discussed. The parameters of the shell-correction and macroscopic parts of the relaxed-density potential are found by fitting the empirical barrier heights of the 89 nucleus-nucleus systems as well as macroscopic potentials evaluated for 1485 nucleus-nucleus systems at 12 distances around touching points.

  1. Neutrino-nucleus interactions

    Energy Technology Data Exchange (ETDEWEB)

    Gallagher, H.; /Tufts U.; Garvey, G.; /Los Alamos; Zeller, G.P.; /Fermilab

    2011-01-01

    The study of neutrino oscillations has necessitated a new generation of neutrino experiments that are exploring neutrino-nuclear scattering processes. We focus in particular on charged-current quasi-elastic scattering, a particularly important channel that has been extensively investigated both in the bubble-chamber era and by current experiments. Recent results have led to theoretical reexamination of this process. We review the standard picture of quasi-elastic scattering as developed in electron scattering, review and discuss experimental results, and discuss additional nuclear effects such as exchange currents and short-range correlations that may play a significant role in neutrino-nucleus scattering.

  2. Antineutron-nucleus annihilation

    CERN Document Server

    Botta, E

    2001-01-01

    The n-nucleus annihilation process has been studied by the OBELIX experiment at the CERN Low Energy Antiproton Ring (LEAR) in the (50-400) MeV/c projectile momentum range on C, Al, Cu, Ag, Sn, and Pb nuclear targets. A systematic survey of the annihilation cross- section, sigma /sub alpha /(A, p/sub n/), has been performed, obtaining information on its dependence on the target mass number and on the incoming n momentum. For the first time the mass number dependence of the (inclusive) final state composition of the process has been analyzed. Production of the rho vector meson has also been examined. (13 refs).

  3. Higgs-Boson Production in Nucleus-Nucleus Collisions

    Science.gov (United States)

    Norbury, John W.

    1992-01-01

    Cross section calculations are presented for the production of intermediate-mass Higgs bosons produced in ultrarelativistic nucleus-nucleus collisions via two photon fusion. The calculations are performed in position space using Baur's method for folding together the Weizsacker-Williams virtual-photon spectra of the two colliding nuclei. It is found that two photon fusion in nucleus-nucleus collisions is a plausible way of finding intermediate-mass Higgs bosons at the Superconducting Super Collider or the CERN Large Hadron Collider.

  4. Source size determination in relativistic nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Nagle, J.L.; Kumar, B.S.; Bennett, M.J.; Diebold, G.E.; Pope, J.K. (Yale University, A. W. Wright Nuclear Structure Laboratory, New Haven, Connecticut 06520-8124 (United States)); Sorge, H.; Sullivan, J.P. (Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States))

    1994-08-29

    We describe a technique whereby the freeze-out interaction volumes of nucleus-nucleus collisions are extracted from a cascade (plus coalescence) model, after comparison to measured abundances of light nuclei. We conclude that the interaction volume undergoes significant expansion before light nuclei are produced.

  5. The Galactic Nucleus

    Science.gov (United States)

    Melia, Fulvio

    Exciting new broadband observations of the galactic nucleus have placed the heart of the Milky Way under intense scrutiny in recent years. This has been due in part to the growing interest from theorists motivated to study the physics of black hole accretion, magnetized gas dynamics, and unusual star formation. The center of our Galaxy is now known to harbor the most compelling supermassive black hole candidate, weighing in at 3-4 million solar masses. Its nearby environment is comprised of a molecular dusty ring, clusters of evolved and young stars, diffuse hot gas, ionized gas streamers, and several supernova remnants. This chapter will focus on the physical makeup of this dynamic region and the feasibility of actually imaging the black hole's shadow in the coming decade with mm interferometry.

  6. Mechanics of the Nucleus

    Science.gov (United States)

    Lammerding, Jan

    2015-01-01

    The nucleus is the distinguishing feature of eukaryotic cells. Until recently, it was often considered simply as a unique compartment containing the genetic information of the cell and associated machinery, without much attention to its structure and mechanical properties. This article provides compelling examples that illustrate how specific nuclear structures are associated with important cellular functions, and how defects in nuclear mechanics can cause a multitude of human diseases. During differentiation, embryonic stem cells modify their nuclear envelope composition and chromatin structure, resulting in stiffer nuclei that reflect decreased transcriptional plasticity. In contrast, neutrophils have evolved characteristic lobulated nuclei that increase their physical plasticity, enabling passage through narrow tissue spaces in their response to inflammation. Research on diverse cell types further demonstrates how induced nuclear deformations during cellular compression or stretch can modulate cellular function. Pathological examples of disturbed nuclear mechanics include the many diseases caused by mutations in the nuclear envelope proteins lamin A/C and associated proteins, as well as cancer cells that are often characterized by abnormal nuclear morphology. In this article, we will focus on determining the functional relationship between nuclear mechanics and cellular (dys-)function, describing the molecular changes associated with physiological and pathological examples, the resulting defects in nuclear mechanics, and the effects on cellular function. New insights into the close relationship between nuclear mechanics and cellular organization and function will yield a better understanding of normal biology and will offer new clues into therapeutic approaches to the various diseases associated with defective nuclear mechanics. PMID:23737203

  7. Neurons of human nucleus accumbens

    Directory of Open Access Journals (Sweden)

    Sazdanović Maja

    2011-01-01

    Full Text Available Background/Aim. Nucleus accumbens is a part of the ventral striatum also known as a drug active brain region, especially related with drug addiction. The aim of the study was to investigate the Golgi morphology of the nucleus accumbens neurons. Methods. The study was performed on the frontal and sagittal sections of 15 human brains by the Golgi Kopsch method. We classified neurons in the human nucleus accumbens according to their morphology and size into four types: type I - fusiform neurons; type II - fusiform neurons with lateral dendrite, arising from a part of the cell body; type III - pyramidal-like neuron; type IV - multipolar neuron. The medium spiny neurons, which are mostly noted regarding to the drug addictive conditions of the brain, correspond to the type IV - multipolar neurons. Results. Two regions of human nucleus accumbens could be clearly recognized on Nissl and Golgi preparations each containing different predominant neuronal types. Central part of nucleus accumbens, core region, has a low density of impregnated neurons with predominant type III, pyramidal-like neurons, with spines on secondary branches and rare type IV, multipolar neurons. Contrary to the core, peripheral region, shell of nucleus, has a high density of impregnated neurons predominantly contained of type I and type IV - multipolar neurons, which all are rich in spines on secondary and tertiary dendritic branches. Conclusion. Our results indicate great morphological variability of human nucleus accumbens neurons. This requires further investigations and clarifying clinical significance of this important brain region.

  8. Heavy flavors in nucleus-nucleus and proton-nucleus collisions

    Directory of Open Access Journals (Sweden)

    Nardi Marzia

    2016-01-01

    Full Text Available A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA and proton-nucleus (pA collisions is presented. The propagation of the heavy quarks in the medium is described in a framework provided by the relativistic Langevin equation, here solved using weak-coupling transport coefficients. Successively, the heavy quarks hadronize in the medium. We compute the nuclear modification factor and the elliptic flow parameter of the final Dmesons both in AA and in pA collisions and compare our results to experimental data.

  9. Heavy flavors in nucleus-nucleus and proton-nucleus collisions

    Science.gov (United States)

    Nardi, Marzia

    2016-11-01

    A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA) and proton-nucleus (pA) collisions is presented. The propagation of the heavy quarks in the medium is described in a framework provided by the relativistic Langevin equation, here solved using weak-coupling transport coefficients. Successively, the heavy quarks hadronize in the medium. We compute the nuclear modification factor and the elliptic flow parameter of the final Dmesons both in AA and in pA collisions and compare our results to experimental data.

  10. A scaling relation between proton-nucleus and nucleus-nucleus collisions

    OpenAIRE

    Basar, Gokce; Teaney, Derek

    2014-01-01

    It is recently discovered that at high multiplicy, the proton-nucleus ($pA$) collisions give rise to two particle correlations that are strikingly similar to those of nucleus-nucleus ($AA$) collisions at the same multiplicity, although the system size is smaller in $pA$. Using an independent cluster model and a simple conformal scaling argument, where the ratio of the mean free path to the system size stays constant at fixed multiplicity, we argue that flow in $pA$ emerges as a collective res...

  11. STAROSNA STRUKTURA VRHUNSKIH RVAČICA

    Directory of Open Access Journals (Sweden)

    Goran Kasum

    2007-05-01

    Full Text Available It’s pretty clear that todays wrestlers must possess comprehensive general and special preparation, rich technical-tactful repertoire, sport’s intelligence, strong nerv system, good motivation and emphasized readiness to carry all training and competitive temptations. These general assumptions were analyzed by many specialists through many different aspects. Some of them emphasized technical preparation as the main factor and others underlined tactful qualifi cation. The most of specialists emphasized the unbreakable unity and connection of technical, tactful, physical and psychological preparation of top wrestlers. Although there are some disagreements about the way of preparation, all specialists agree that good selection of candidates is necessary for the top results. Candidate’s age and his fi ttnes in age characteristics specifi cal for certain category are one of the main criterion for selection. It’s not rare coaches give up the most qualifi ed competitor at that moment with the reason that the competitor won’t be able to be a candidate for the highest standing at the time of Olimpics. In this essey, special attention is commited to the analyze of age-structure of womens wrestlers with the special Athens Olimpics 2004. review

  12. Optimalna starostna struktura intenzivnega nasada jablan

    OpenAIRE

    Šipek, Lidija

    2014-01-01

    Namen magistrskega dela je finančna ocena investicij obnove intenzivnega nasada jablan po 15-tih letih polne rodnosti, po 20-tih letih polne rodnosti (v starosti 25 let) in obnova šele v 30. letu starosti nasada. Osnovni cilj je celovita finančna analiza investicij sadjarske kmetije s statično in dinamično metodo ocene investicijskih projektov. Parametri ocenjevanja investicij so bili ocenjeni s pomočjo izračunov v računalniškem programu Microsft Office Excel. Po finančni oceni je najboljša d...

  13. Struktura političke znanosti

    OpenAIRE

    Strpić, Dag

    1997-01-01

    Ministarstvo znanosti Republike Hrvatske donijelo je novi Pravilnik o utvrđivanju znanstvenih područja. Po njemu je Politologija, znanstveno polje područja društvenih znanosti te podijeljeno na: 1. Politologiju, 2. Teoriju i povijest politike, te 3. Političku filozofiju. Autor dokumentirano navodi kako Političku znanost sasvim drukčije strukturiraju IPSA i APSA, te prikazuje 120 godina dominantno američkog razvoja političke znanosti i politoloških profesija, koji je doveo do novoga svjetskog ...

  14. STRUKTURA DRUŠTVENIH STAVOVA U HRVATSKOJ

    OpenAIRE

    Milas, Goran; RIHTAR, Stanko

    1998-01-01

    Radom su se nastojale otkriti temeljne organizacijske odrednice društvenih stavova u Hrvatskoj. Problem je razložen na dvije razine, metodološkoj i kulturalnoj. Anketno istraživanje provedeno je u dvjema vremenskim točkama, u ratnom vremenu 1992. i nakon završetka ratnih operacija 1996./97. U prvom dijelu istraživanja ispitan je reprezentativan uzorak Hrvatske (2366) a u drugom uzorak polaznika zagrebačkih gimnazija (444). Primijenjena su dva mjerna instrumenta s repre...

  15. Charged pion anisotropy in relativistic nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Poitou, J.; L' Hote, D.; Cavata, C.; Babinet, R.; Demoulins, M.; Fanet, H.; Gosset, J.; Lemaire, M.C.; Le Merdy, A.; Lucas, B.; Terrien, Y.; Valette, O. (CEN Saclay, 91 - Gif-sur-Yvette (France)); Alard, J.P.; Augerat, J.; Bastid, N.; Charmensat, P.; Dupieux, P.; Fraysse, L.; Marroncle, J.; Montarou, G.; Parizet, M.J.; Rahmani, A. (LPC Clermont-Ferrand, 63 - Aubiere (France)); Brochard, F.; Gorodetzky, P.; Racca, C. (CRN, 67 - Strasbourg (France))

    1992-01-27

    The momentum distributions with respect to the reaction plane for charged pions emitted in Ne-nucleus and Ar-nucleus collisions have been measured with the 4{pi} detector Diogene at the Saturne synchrotron. The reaction plane is estimated from the baryon momenta, using a standard technique for flow analysis. The pions exhibit a non-zero flow. For asymmetric systems, there is a preferential emission in the direction of the lighter (projectile) nucleus. Such a behaviour contradicts the predictions of INC calculations and is underestimated by QMD calculations which include mean field effects. It can be interpreted with a simple geometrical model in terms of absorption by the spectator nuclear matter. (orig.).

  16. Quasielastic K-nucleus scattering

    CERN Document Server

    Pace, A D; Oset, E

    1997-01-01

    Quasielastic K^+ - nucleus scattering data at q=290, 390 and 480 MeV/c are analyzed in a finite nucleus continuum random phase approximation framework, using a density-dependent particle-hole interaction. The reaction mechanism is consistently treated according to Glauber theory, keeping up to two-step inelastic processes. A good description of the data is achieved, also providing a useful constraint on the strength of the effective particle-hole interaction in the scalar-isoscalar channel at intermediate momentum transfers. We find no evidence for the increase in the effective number of nucleons participating in the reaction which has been reported in the literature.

  17. Heavy-ion nucleus scattering

    CERN Document Server

    Rahman, M A; Haque, S

    2003-01-01

    Heavy ion-nucleus scattering is an excellent laboratory to probe high spin phenomena, exotic nuclei and for the analysis of various exit channels. The Strong Absorption Model or the generalized diffraction models, which are semi-classical in nature, have been employed in the description of various heavy ion-nucleus scattering phenomena with reasonable success. But one needs to treat the deflection function (scattering angles) quantum mechanically in the Wave Mechanical picture for the appropriate description of the heavy-ion nucleus scattering phenomena. We have brought the mathematics for the cross-section of the heavy-ion nucleus scattering to an analytic expression taking account of the deflection function (scattering angles) quantum mechanically. sup 9 Be, sup 1 sup 6 O, sup 2 sup 0 Ne and sup 3 sup 2 S heavy-ion beams elastic scattering from sup 2 sup 8 Si, sup 2 sup 4 Mg and sup 4 sup 0 Ca target nuclei at various projectile energies over the range 20-151 MeV have been analysed in terms of the 2-paramet...

  18. Dimuon enhancement in nucleus-nucleus ultrarelativistic interactions

    Energy Technology Data Exchange (ETDEWEB)

    Bordalo, Paula; Abreu, M.C.; Alessandro, B.; Alexa, C.; Arnaldi, R.; Astruc, J.; Atayan, M.; Baglin, C.; Baldit, A.; Bedjidian, M.; Bellaiche, F.; Beole, S.; Bohrani, A.; Boldea, V.; Bussiere, A.; Capelli, L.; Caponi, V.; Casagrande, L.; Castor, J.; Chambon, T.; Chaurand, B.; Chevrot, I.; Cheynis, B.; Chiavassa, E.; Cicalo, C.; Comets, M.P.; Constans, N.; Constantinescu, S.; Contardo, D.; Cruz, J.; De Falco, A.; De Marco, N.; Dellacasa, G.; Devaux, A.; Dita, S.; Drapier, O.; Ducroux, L.; Espagnon, B.; Fargeix, J.; Ferreira, R.; Filippov, S.N.; Fleuret, F.; Force, P.; Gallio, M.; Gavrilov, Y.K.; Gerschel, C.; Giubellino, P.; Golubeva, M.B.; Gonin, M.; Gorodetzky, P.; Grigorian, A.A.; Grossiord, J.Y.; Guber, F.F.; Guichard, A.; Gulkanyan, H.; Hakobyan, R.; Haroutunian, R.; Idzik, M.; Jouan, D.; Karavitcheva, T.L.; Kluberg, L.; Kossakowski, R.; Kurepin, A.B.; Landau, G.; Le Bornec, Y.; Lourenco, C.; Luquin, L.; Macciotta, P.; Mac Cormick, M.; Mandry, R.; Marzari-Chiesa, A.; Masera, M.; Masoni, A.; Mehrabyan, S.; Monteno, M.; Mourgues, S.; Musso, A.; Ohlsson-Malek, F.; Petiau, P.; Piccotti, A.; Pizzi, J.R.; Prado da Silva, W.L.; Puddu, G.; Quintans, C.; Racca, C.; Ramello, L.; Ramos, S.; Rato-Mendes, P.; Riccati, L.; Romana, A.; Ropotar, I.; Saturnini, P.; Scomparin, E.; Serci, S.; Shahoyan, R.; Silva, S.; Sitta, M.; Soave, C.; Sonderegger, P.; Tarrago, X.; Topilskaya, N.S.; Usai, G.L.; Varela, J.; Vercellin, E.; Villatte, L

    1999-12-27

    The study of muon pairs in the mass region 1.5 < M{sub {mu}}{sub {mu}} < 2.5 GeV/c{sup 2} in 450 GeV/c p-A, 200 GeV/nucleon S-U and 158 GeV/nucleon Pb-Pb collisions is presented. In p-A interactions, the dimuon signal mass spectra are well described by a superposition of Drell-Yan and charmed meson semi-leptonic decay contributions, in agreement with previous experiments when considering a linear A dependence. In nucleus-nucleus reactions, taking only into account these two physical ingredients, a dimuon enhancement both with increasing A{center_dot}B and centrality is observed.

  19. Azimuthal correlation and collective behavior in nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Mali, P.; Mukhopadhyay, A., E-mail: amitabha-62@rediffmail.com; Sarkar, S. [University of North Bengal, Department of Physics (India); Singh, G. [SUNY at Fredonia, Department of Computer and Information Science (United States)

    2015-03-15

    Various flow effects of nuclear and hadronic origin are investigated in nucleus-nucleus collisions. Nuclear emulsion data collected from {sup 84}Kr + Ag/Br interaction at an incident energy of 1.52 GeV per nucleon and from {sup 28}Si + Ag/Br interaction at an incident energy of 14.5 GeV per nucleon are used in the investigation. The transverse momentum distribution and the flow angle analysis show that collective behavior, like a bounce-off effect of the projectile spectators and a sidesplash effect of the target spectators, are present in our event samples. From an azimuthal angle analysis of the data we also see a direct flow of the projectile fragments and of the produced charged particles. On the other hand, for both data samples the target fragments exhibit a reverse flow, while the projectile fragments exhibit an elliptic flow. Relevant flow parameters are measured.

  20. Transverse Energy in nucleus-nucleus collisions: A review

    Energy Technology Data Exchange (ETDEWEB)

    Tincknell, M.

    1988-11-15

    The status of Transverse Energy (E/sub T/) in relativistic nucleus-nucleus collisions at the Brookhaven AGS and the CERN SPS is reviewed. The definition of E/sub T/ and its physical significance are discussed. The basic techniques and limitations of the experimental measurements are presented. The acceptances of the major experiments to be discussed are shown, along with remarks about their idiosyncrasies. The data demonstrate that the nuclear geometry of colliding spheres primarily determines the shapes of the observed spectra. Careful account of the acceptances is crucial to comparing and interpreting results. It is concluded that nuclear stopping power is high, and that the amount of energy deposited into the interaction volume is increasing with beam energy even at SPS energies. The energy densities believed to be obtained at the SPS are close to the critical values predicted for the onset of a quark-gluon plasma. 25 refs., 8 figs.

  1. Atom as a "Dressed" Nucleus

    CERN Document Server

    Kalitvianski, V

    2008-01-01

    It is shown that electrostatic potential of atomic nucleus seen by a fast charged projectile at short distances is quite smeared due to nucleus motion around the atomic center of inertia. For example, the size of positive charge cloud in the Hydrogen ground state is much larger than the proper proton size. It is even bigger for the target atom in an excited state. Therefore the elastic scattering at large angles is generally weaker than the Rutherford one. In other words, the resulting elastic interaction with an atom at short distances is softer than the Colombian one due to a natural cutoff. In addition, the large angle scattering leads to the target atom excitations due to hitting the nucleus (inelastic processes). It is also shown that the Rutherford cross section is in fact the inclusive rather than the elastic one. These results are analogous to the QED ones. The difference and the value of the presented below non relativistic atomic calculations is in non perturbatively (exact) dressing that immediatel...

  2. Classifiers for centrality determination in proton-nucleus and nucleus-nucleus collisions

    CERN Document Server

    Altsybeev, Igor

    2016-01-01

    Centrality, as a geometrical property of the collision, is crucial for the physical interpretation of nucleus-nucleus and proton-nucleus experimental data. However, it cannot be directly accessed in event-by-event data analysis. Common methods for centrality estimation in A-A and p-A collisions usually rely on a single detector (either on the signal in zero-degree calorimeters or on the multiplicity in some semi-central rapidity range). In the present work, we made an attempt to develop an approach for centrality determination that is based on machine-learning techniques and utilizes information from several detector subsystems simultaneously. Different event classifiers are suggested and evaluated for their selectivity power in terms of the number of nucleons-participants and the impact parameter of the collision. Finer centrality resolution may allow to reduce impact from so-called volume fluctuations on physical observables being studied in heavy-ion experiments like ALICE at the LHC and fixed target exper...

  3. Pion production and absorption in relativistic nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Senger, P. [GSI Planckstr.1, Darmstadt (Germany)

    1993-12-31

    In a relativistic nucleus-nucleus collision the projectile kinetic energy is not only converted into thermal and compressional energy of the nucleonic system, but also into internal excitation energy of the nucleons. At bombarding energies around 1 GeV/nucleon a substantial amount of baryonic resonances is produced which decay predominantly into pions. Thus the pion multiplicity, momentum and angular distributions provide information on the space time dynamics of the nuclear reaction system. In this paper the authors report on experiments which try to measure the `primordial` delta or pion abundancy. The idea is to compare the pion yields measured in a heavy and a light system: in the first case pion final-state interactions should happen much more frequently than in the second case. Both inclusive pion cross sections and pion multiplicities per participant nucleon are measured. In addition the authors study the pion emission pattern with respect to the reaction plane to sort out pions which are less affected by absorption and rescattering even in a heavy collision system.

  4. Relativistic nucleus-nucleus collisions and the QCD phase diagram

    CERN Document Server

    Stock, Reinhard

    2005-01-01

    A steep maximum occurs in the Wroblewski ratio between strange and non-strange quarks created in central nucleus-nucleus collisions, of about A=200, at the lower SPS energy square root s approximately= 7 GeV. By analyzing hadronic multiplicities within the grand canonical statistical hadronization model this maximum is shown to occur at a baryochemical potential of about 450 MeV. In comparison, recent QCD lattice calculations at finite baryochemical potential suggest a steep maximum of the light quark susceptibility, to occur at similar mu /sub B/, indicative of "critical fluctuation" expected to occur at or near the QCD critical endpoint. This endpoint had not been firmly pinned down but should occur in the 300 MeV < mu /sub B//sup c/ < 700 MeV interval. It is argued that central collisions within the low SPS energy range should exhibit a turning point between compression /heating, and expansion/cooling at energy density, temperature and mu /sub B/ close to the suspected critical point. Whereas from to...

  5. Resonances in -light nucleus systems

    Indian Academy of Sciences (India)

    K P Khemchandani; N G Kelkar; M Nowakowski; B K Jain

    2006-04-01

    We locate resonances in -light nucleus elastic scattering using the time delay method. We solve few-body equations within the finite rank approximation in order to calculate the -matrices and hence the time delay for the - 3He and - 4He systems. We find a resonance very close to the threshold in - 3 He elastic scattering, at about 0.5 MeV above threshold with a width of ∼ 2 MeV. The calculations also hint at the presence of sub-threshold states in both the cases.

  6. Turbulent mixing condensation nucleus counter

    Science.gov (United States)

    Mavliev, Rashid

    The construction and operating principles of the Turbulent Mixing Condensation Nucleus Counter (TM CNC) are described. Estimations based on the semiempirical theory of turbulent jets and the classical theory of nucleation and growth show the possibility of detecting particles as small as 2.5 nm without the interference of homogeneous nucleation. This conclusion was confirmed experimentally during the International Workshop on Intercomparison of Condensation Nuclei and Aerosol Particle Counters (Vienna, Austria). Number concentration, measured by the Turbulent Mixing CNC and other participating instruments, is found to be essentially equal.

  7. Determination of Coil Inductances Cylindrical Iron Nucleus

    Directory of Open Access Journals (Sweden)

    Azeddine Mazouz

    2014-03-01

    Full Text Available The paper describes the investigation and development of a structure and performance characteristics of a coil iron nucleus cylindrical (C.I.N.C. The coil iron nucleus cylindrical is a nonlinear electro radio in which the moving of the nucleus in a sense or in other causes change in inductance and can reach extreme values at the superposition of nucleus and coil centers. The variation of the inductance and the degree of freedom of movement of the nucleus can lead to a device with electromechanical conversion The aim of this paper is the determination and visualization of self inductance and mutual of the (C.I.N.C based on geometric dimensions and the displacement of the nucleus.  

  8. Projections from the central amygdaloid nucleus to the precuneiform nucleus in the mouse.

    Science.gov (United States)

    Liang, Huazheng; Watson, Charles; Paxinos, George

    2015-01-01

    The mouse precuneiform nucleus has been proposed as the midbrain locomotion center, a function ascribed to its caudal neighbor, cuneiform nucleus, in the rat, cat and other species. The present study investigated the projections from the central amygdaloid nucleus to the precuneiform nucleus in the mouse using retrograde tracer injections (fluoro-gold) into the precuneiform nucleus and anterograde tracer injections (biotinylated dextran amine) into the central amygdaloid nucleus. The entire central amygdaloid nucleus except the rostral pole had retrogradely labeled neurons, especially in the middle portion where labeled neurons were densely packed. Anterogradely labeled amygdaloid fibers approached the precuneiform nucleus from the area ventrolateral to it and terminated in the entire precuneiform nucleus. Labeled fibers were also found in laminae 5 and 6 in the upper cervical cord on the ipsilateral side. The present study is the first demonstration of projections from the central amygdaloid nucleus to the precuneiform nucleus. This projection may underpin the role of the precuneiform nucleus in the modulation of the cardiovascular activity.

  9. Crossing axons in the third nerve nucleus.

    Science.gov (United States)

    Bienfang, D C

    1975-12-01

    The research presented in this paper studied the pathway taken by the crossed fibers of the third nerve nucleus in an animal whose nucleus has been well mapped and found to correlate well with higher mammals and man. Autoradiography using tritiated amino acid labeled the cell bodies an axons of the left side of the oculomotor nucleus of the cat. Axons so labeled could be seen emerging from the ventral portion of the left nucleus through the median longitudinal fasciculus (mlf) to join the left oculomotor nerve. Labeled axons were also seen to emerge from the medial border of the caudal left nucleus, cross the midline, and pass through the right nucleus and the right mlf to join the right oculomotor nerve. These latter axons must be the crossed axons of the superior rectus and levator palpebrae subnuclei. Since the path of these crossed axons is through the caudal portion of the nucleus of the opposite side, the destruction of one lateral half of the oculomotor nucleus would result in a bilateral palsy of the crossed subnuclei. Bilateral palsy of the superior rectus and bilateral assymetrical palsy of the levator palpebrae muscles would result.

  10. Music and the nucleus accumbens.

    Science.gov (United States)

    Mavridis, Ioannis N

    2015-03-01

    Music is a universal feature of human societies over time, mainly because it allows expression and regulation of strong emotions, thus influencing moods and evoking pleasure. The nucleus accumbens (NA), the most important pleasure center of the human brain (dominates the reward system), is the 'king of neurosciences' and dopamine (DA) can be rightfully considered as its 'crown' due to the fundamental role that this neurotransmitter plays in the brain's reward system. Purpose of this article was to review the existing literature regarding the relation between music and the NA. Studies have shown that reward value for music can be coded by activity levels in the NA, whose functional connectivity with auditory and frontal areas increases as a function of increasing musical reward. Listening to music strongly modulates activity in a network of mesolimbic structures involved in reward processing including the NA. The functional connectivity between brain regions mediating reward, autonomic and cognitive processing provides insight into understanding why listening to music is one of the most rewarding and pleasurable human experiences. Musical stimuli can significantly increase extracellular DA levels in the NA. NA DA and serotonin were found significantly higher in animals exposed to music. Finally, passive listening to unfamiliar although liked music showed activations in the NA.

  11. Study of Hadron Production in Hadron-Nucleus and Nucleus-Nucleus Collisions at the CERN SPS

    CERN Multimedia

    Selyuzhenkov, I; Klochkov, V; Kowalski, S; Kaptur, E A; Kowalik, K L; Dominik, W M; Krasnoperov, A; Feofilov, G; Vinogradov, L; Kovalenko, V; Johnson, S R; Mills, G B; Planeta, R J; Rubbia, A; Marton, K; Messerly, B A; Puzovic, J; Bogomilov, M V; Bravar, A; Sgalaberna, D; Renfordt, R A E; Deveaux, M; Engel, R R; Grzeszczuk, A; Davis, N; Kuich, M; Lyubushkin, V; Kondratev, V; Kadija, K; Diakonos, F; Slodkowski, M A; Rauch, W H; Pistillo, C; Laszlo, A; Nakadaira, T; Hasegawa, T; Sadovskiy, A; Morozov, S; Petukhov, O; Szuba, M K; Mathes, H; Herve, A E; Roehrich, D; Marino, A D; Grebieszkow, K; Wlodarczyk, Z; Rybczynski, M A; Wojtaszek-szwarc, A; Nirkko, M C; Sakashita, K; Golubeva, M; Kurepin, A; Manic, D; Kolev, D I; Kisiel, J E; Rondio, E; Larsen, D T; Czopowicz, T R; Seyboth, P; Turko, L; Guber, F; Marin, V; Busygina, O; Taranenko, A; Cirkovic, M; Gazdzicki, M; Roth, M A; Pulawski, S M; Aduszkiewicz, A M; Bunyatov, S; Vechernin, V; Nagai, Y; Anticic, T; Dynowski, K M; Mackowiak-pawlowska, M K; Stefanek, G; Pavin, M; Fodor, Z P; Nishikawa, K; Tada, M; Kobayashi, T; Blondel, A P P; Damyanova, A; Stroebele, H W; Posiadala, M Z; Kolesnikov, V; Andronov, E; Zimmerman, E D; Antoniou, N; Majka, Z; Di luise, S; Veberic, D; Dumarchez, J; Naskret, M; Ivashkin, A; Tsenov, R V; Koziel, M G; Schmidt, K J; Melkumov, G; Popov, B; Panagiotou, A; Richter-was, E M; Ereditato, A; Paolone, V; Unger, M T; Wilczek, A G; Stepaniak, J M; Matulewicz, T N; Seryakov, A; Susa, T; Staszel, P P; Brzychczyk, J; Maksiak, B; Tefelski, D B; Kucewicz, W; Dorosz, P A

    2007-01-01

    The NA61/SHINE (SHINE = SPS Heavy Ion and Neutrino Experiment) experiment is a large acceptance hadron spectrometer at the CERN SPS for the study of the hadronic final states produced in interactions of various beam particles (pions, protons, C, S and In) with a variety of fixed targets at the SPS energies. The main components of the current detector were constructed and used by the NA49 experiment. The physics program of NA61/SHINE consists of three main subjects. In the first stage of data taking (2007-2009) measurements of hadron production in hadron-nucleus interactions needed for neutrino (T2K) and cosmic-ray (Pierre Auger and KASCADE) experiments will be performed. In the second stage (2009-2011) hadron production in proton-proton and proton-nucleus interactions needed as reference data for a better understanding of nucleus-nucleus reactions will be studied. In the third stage (2009-2013) energy dependence of hadron production properties will be measured in nucleus-nucleus collisions as well as in p+p a...

  12. Large philipsite crystal as ferromanganese nodule nucleus

    Digital Repository Service at National Institute of Oceanography (India)

    Ghosh, A.K.; Mukhopadhyay, R.

    We report here the occurrence of, to date, the largest (21 x 10 x 8 mm) phillipsite crystal forming the nucleus of a diagenetically formed ferromanganese nodule from the Central Indian Ocean Basin (CIOB). Assuming an average rate of ferromanganese...

  13. Medium effect in high density region probed by nucleus-nucleus elastic scattering

    CERN Document Server

    Furumoto, T; Yamamoto, Y

    2014-01-01

    We investigate the sensitivity of the medium effect in the high density region on the nucleus-nucleus elastic scattering in the framework of the double-folding (DF) model with the complex $G$-matrix interaction. First, the evaluating position of the local density, which is an ambiguity of the DF model, is investigated. However, the effect has a minor role to the nucleus-nucleus system. Next, the medium effect including three-body-force (TBF) effect is investigated with two methods. In the both methods, the medium effect is clearly seen on the potential and the elastic cross section, but not on the total reaction cross section. Finally, we make clear the crucial role of the TBF effect up to $k_F =$ 1.6 fm$^{-1}$ in the nucleus-nucleus elastic scattering.

  14. Transport calculations of antiproton-nucleus interactions

    CERN Document Server

    Larionov, A B; Pshenichnov, I A; Satarov, L M; Greiner, W

    2010-01-01

    The Giessen Boltzmann-Uehling-Uhlenbeck transport model is extended and applied to the antiproton-nucleus interactions in a wide beam momentum range. The model calculations are compared with the experimental data on $\\bar p$-absorption cross sections on nuclei with an emphasis on extraction of the real part of an antiproton optical potential. The possibility of the cold compression of a nucleus by an antiproton in-flight is also considered.

  15. Commissural axons of the mouse cochlear nucleus.

    Science.gov (United States)

    Brown, M Christian; Drottar, Marie; Benson, Thane E; Darrow, Keith

    2013-05-01

    The axons of commissural neurons that project from one cochlear nucleus to the other were studied after labeling with anterograde tracer. Injections were made into the dorsal subdivision of the cochlear nucleus in order to restrict labeling only to the group of commissural neurons that gave off collaterals to, or were located in, this subdivision. The number of labeled commissural axons in each injection was correlated with the number of labeled radiate multipolar neurons, suggesting radiate neurons as the predominant origin of the axons. The radiate commissural axons are thick and myelinated, and they exit the dorsal acoustic stria of the injected cochlear nucleus to cross the brainstem in the dorsal half, near the crossing position of the olivocochlear bundle. They enter the opposite cochlear nucleus via the dorsal and ventral acoustic stria and at its medial border. Reconstructions of single axons demonstrate that terminations are mostly in the core and typically within a single subdivision of the cochlear nucleus. Extents of termination range from narrow to broad along both the dorsoventral (i.e., tonotopic) and the rostrocaudal dimensions. In the electron microscope, labeled swellings form synapses that are symmetric (in that there is little postsynaptic density), a characteristic of inhibitory synapses. Our labeled axons do not appear to include excitatory commissural axons that end in edge regions of the nucleus. Radiate commissural axons could mediate the broadband inhibition observed in responses to contralateral sound, and they may balance input from the two ears with a quick time course.

  16. BFKL Pomeron calculus: solution to equations for nucleus-nucleus scattering in the saturation domain

    CERN Document Server

    Contreras, Carlos; Meneses, Rodrigo

    2013-01-01

    In this paper we solve the equation for nucleus-nucleus scattering in the BFKL Pomeron calculus, suggested by Braun. We find these solutions analytically at high energies as well as numerically in the entire region of energies inside the saturation region. The semi-classical approximation is used to select out the infinite set of the parasite solutions. The nucleus-nucleus cross sections at high energy are estimated and compared with the Glauber-Gribov approach. It turns out that the exact formula gives the estimates that are very close to the ones based on Glauber-Gribov formula which is important for the practical applications

  17. Onset of Deconfinement in Nucleus-Nucleus Collisions - Past, Present and Future -

    CERN Document Server

    Gazdzicki, Marek

    2007-01-01

    In 2007 Mark I. Gorenstein celebrated his 60th birthday. This report is dedicated to Mark and it sketches the results obtained during the past ten years of our collaboration and friendship. They concern search for and study of the onset of deconfinement in high energy nucleus-nucleus collisions.

  18. High density QCD and nucleus-nucleus scattering deeply in the saturation region

    Science.gov (United States)

    Kormilitzin, Andrey; Levin, Eugene; Miller, Jeremy S.

    2011-06-01

    In this paper we solve the equations that describe nucleus-nucleus scattering, in high density QCD, in the framework of the BFKL Pomeron Calculus. We found that (i) the contribution of short distances to the opacity for nucleus-nucleus scattering dies at high energies, (ii) the opacity tends to unity at high energy, and (iii) the main contribution that survives comes from soft (long distance) processes for large values of the impact parameter. The corrections to the opacity Ω(Y,b)=1 were calculated and it turns out that they have a completely different form, namely ( 1-Ω→exp(-Const √{Y} )) than the opacity that stems from the Balitsky-Kovchegov equation, which is ( 1-Ω→exp(-Const Y)). We reproduce the formula for the nucleus-nucleus cross section that is commonly used in the description of nucleus-nucleus scattering, and there is no reason why it should be correct in the Glauber-Gribov approach.

  19. Control of nucleus positioning in mouse oocytes.

    Science.gov (United States)

    Almonacid, Maria; Terret, Marie-Emilie; Verlhac, Marie-Hélène

    2017-08-12

    The position of the nucleus in a cell can instruct morphogenesis in some cases, conveying spatial and temporal information and abnormal nuclear positioning can lead to disease. In oocytes from worm, sea urchin, frog and some fish, nucleus position regulates embryo development, it marks the animal pole and in Drosophila it defines the future dorso-ventral axis of the embryo and of the adult body plan. However, in mammals, the oocyte nucleus is centrally located and does not instruct any future embryo axis. Yet an off-center nucleus correlates with poor outcome for mouse and human oocyte development. This is surprising since oocytes further undergo two extremely asymmetric divisions in terms of the size of the daughter cells (enabling polar body extrusion), requiring an off-centering of their chromosomes. In this review we address not only the bio-physical mechanism controlling nucleus positioning via an actin-mediated pressure gradient, but we also speculate on potential biological relevance of nuclear positioning in mammalian oocytes and early embryos. Copyright © 2017. Published by Elsevier Ltd.

  20. Organisation of the human dorsomedial hypothalamic nucleus.

    Science.gov (United States)

    Koutcherov, Yuri; Mai, Juergen K; Ashwell, Ken W; Paxinos, George

    2004-01-19

    This study used acetylcholinesterase (AChE) histochemistry to reveal the organization of the dorsomedial hypothalamic nucleus (DM) in the human. Topographically, the human DM is similar to DM in the monkey and rat. It is wedged between the paraventricular nucleus, dorsally, and the ventromedial nucleus, ventrally. Laterally, DM borders the lateral hypothalamic area while medially it approaches the 3rd ventricle. The AChE staining distinguished two subcompartments of the human DM: the larger diffuse and the smaller compact DM. The subcompartmental organization of the human DM appears homologous to that found in the monkey and less complex than that reported in rats. Understanding of the organization of DM creates meaningful anatomical reference for physiological and pharmacological studies in the human hypothalamus.

  1. The nucleus: a black box being opened.

    Science.gov (United States)

    van Driel, R; Humbel, B; de Jong, L

    1991-12-01

    Until recently our knowledge about the structural and functional organization of the cell nucleus was very limited. Recent technical developments in the field of ultrastructural analysis, combined with ongoing research on the properties of the nuclear matrix, give new insight into how the nucleus is structured. Two types of observations shape our ideas about nuclear organization. First, most nuclear functions (replication, transcription, RNA processing, and RNA transport) are highly localized within the nucleus, rather than diffusely distributed. Moreover, they are associated with the nuclear matrix. Second, chromatin is organized in discrete loops, bordered by nuclear matrix attachment sequences (MARs). Each loop may contain one or several genes. The arrangement of chromatin in loops has profound consequences for the regulation of gene expression.

  2. Dirac Phenomenology and Hyperon-Nucleus Interactions

    OpenAIRE

    J., MARES; B. K., JENNINGS; E. D., COOPER; Triumf, 4004 Wesbrook Mall; Department of Physics, University College of the Fraser Valley

    1995-01-01

    We discuss various aspects of hyperon-nucleus interactions in the relativistic mean field theory. First, characteristics of Λ, Σ and Ξ hypernuclei, as well as multi-strange baryonic objects, are investigated. The spin-orbit splittings and magnetic moments are shown to be very sensitive to the value of the tensor coupling f_. Second, optical potentials for Λ and Σ scattering off nuclei are developed based on a global nucleon-nucleus Dirac optical potential and SU(3) symmetry. The tensor coupli...

  3. UNCOVERING THE NUCLEUS CANDIDATE FOR NGC 253

    Energy Technology Data Exchange (ETDEWEB)

    Günthardt, G. I.; Camperi, J. A. [Observatorio Astronómico, Universidad Nacional de Córdoba (Argentina); Agüero, M. P. [Observatorio Astronómico, Universidad Nacional de Córdoba, and CONICET (Argentina); Díaz, R. J.; Gomez, P. L.; Schirmer, M. [Gemini Observatory, AURA (United States); Bosch, G., E-mail: gunth@oac.uncor.edu, E-mail: camperi@oac.uncor.edu, E-mail: mpaguero@oac.uncor.edu, E-mail: rdiaz@gemini.edu, E-mail: pgomez@gemini.edu, E-mail: mschirmer@gemini.edu, E-mail: guille@fcaglp.unlp.edu.ar [Instituto de Astrofísica de La Plata (CONICET-UNLP) (Argentina)

    2015-11-15

    NGC 253 is the nearest spiral galaxy with a nuclear starburst that becomes the best candidate for studying the relationship between starburst and active galactic nucleus activity. However, this central region is veiled by large amounts of dust, and it has been so far unclear which is the true dynamical nucleus to the point that there is no strong evidence that the galaxy harbors a supermassive black hole co-evolving with the starburst as was supposed earlier. Near-infrared (NIR) spectroscopy, especially NIR emission line analysis, could be advantageous in shedding light on the true nucleus identity. Using Flamingos-2 at Gemini South we have taken deep K-band spectra along the major axis of the central structure and through the brightest infrared source. In this work, we present evidence showing that the brightest NIR and mid-infrared source in the central region, already known as radio source TH7 and so far considered just a large stellar supercluster, in fact presents various symptoms of a genuine galactic nucleus. Therefore, it should be considered a valid nucleus candidate. Mentioning some distinctive aspects, it is the most massive compact infrared object in the central region, located at 2.″0 of the symmetry center of the galactic bar, as measured in the K-band emission. Moreover, our data indicate that this object is surrounded by a large circumnuclear stellar disk and it is also located at the rotation center of the large molecular gas disk of NGC 253. Furthermore, a kinematic residual appears in the H{sub 2} rotation curve with a sinusoidal shape consistent with an outflow centered in the candidate nucleus position. The maximum outflow velocity is located about 14 pc from TH7, which is consistent with the radius of a shell detected around the nucleus candidate, observed at 18.3 μm (Qa) and 12.8 μm ([Ne ii]) with T-ReCS. Also, the Brγ emission line profile shows a pronounced blueshift and this emission line also has the highest equivalent width at this

  4. Nucleus-Nucleus Potential at Near-Barrier Energies from Self Consistent Calculations

    CERN Document Server

    Skalski, J

    2003-01-01

    We determine the static nucleus-nucleus potential from Hartree-Fock (HF) calculations with the Skyrme interaction. To this aim, HF equations are solved on a spatial mesh, with the initial configuration consisting of target and projectile positioned at various relative distances. For a number of reaction partners, the calculated barrier heights reasonably well compare with those extracted from the measured fusion and capture cross sections. At smaller target-projectile distances, our results show the intrinsic barriers to heavy compound nucleus formation. We speculate on their possible connection with the fusion hindrance observed for large Z sub T Z sub P.

  5. Inner Structure of Boiling Nucleus and Interfacial Energy Between Nucleus and Bulk Liquid

    Institute of Scientific and Technical Information of China (English)

    WANG Xiao-Dong; TIAN Yong; PENG Xiao-Feng; WANG Bu-Xuan

    2004-01-01

    @@ A model of two-region structure of a nucleus is proposed to describe nucleus evolution. The interfacial tension between bulk liquid phase and nucleus is dependent on the density gradient in the transition region and varies with the structure change of the transition region. With the interfacial tension calculated using this model, the predicted nucleation rate is very close to the experimental measurement. Furthermore, this model and associated analysis provide solid theoretical evidence to clarify the definition of nucleation rate and understand the nucleation phenomenon with insight into the physical nature.

  6. Nucleus-associated actin in Amoeba proteus.

    Science.gov (United States)

    Berdieva, Mariia; Bogolyubov, Dmitry; Podlipaeva, Yuliya; Goodkov, Andrew

    2016-10-01

    The presence, spatial distribution and forms of intranuclear and nucleus-associated cytoplasmic actin were studied in Amoeba proteus with immunocytochemical approaches. Labeling with different anti-actin antibodies and staining with TRITC-phalloidin and fluorescent deoxyribonuclease I were used. We showed that actin is abundant within the nucleus as well as in the cytoplasm of A. proteus cells. According to DNase I experiments, the predominant form of intranuclear actin is G-actin which is associated with chromatin strands. Besides, unpolymerized actin was shown to participate in organization of a prominent actin layer adjacent to the outer surface of nuclear envelope. No significant amount of F-actin was found in the nucleus. At the same time, the amoeba nucleus is enclosed in a basket-like structure formed by circumnuclear actin filaments and bundles connected with global cytoplasmic actin cytoskeleton. A supposed architectural function of actin filaments was studied by treatment with actin-depolymerizing agent latrunculin A. It disassembled the circumnuclear actin system, but did not affect the intranuclear chromatin structure. The results obtained for amoeba cells support the modern concept that actin is involved in fundamental nuclear processes that have evolved in the cells of multicellular organisms.

  7. An organism arises from every nucleus.

    Directory of Open Access Journals (Sweden)

    Nurullah Keklikoglu

    2009-12-01

    Full Text Available The fact that, cloning using somatic cell nuclear transfer (SCNT method has been performed, opened new horizons for cloning, and changed the way of our understanding and approach to cell and nucleus. The progress in cloning technology, brought the anticipation of the ability to clone an organism from each somatic cell nucleus. Therefore, the 'Cell Theory' is about to take the additional statement as "An organism arises from every nucleus". The development of gene targeting procedures which can be applied with SCNT, showed us that it may be possible to obtain different versions of the original genetic constitution of a cell. Because of this opportunity which is provided by SCNT, in reproductive cloning, it would be possible to clone enhanced organisms which can adapt to different environmental conditions and survive. Furthermore, regaining the genetic characteristics of ancestors or reverse herediter variations would be possible. On the other hand, in therapeutic cloning, more precise and easily obtainable alternatives for cell replacement therapy could be presented. However, while producing healthier or different organisms from a nucleus, it is hard to foresee the side effects influencing natural processes in long term is rather difficult.

  8. Uncovering the nucleus candidate for NGC 253

    CERN Document Server

    Günthardt, G I; Camperi, J A; Díaz, R J; Gomez, P L; Bosch, G; Schirmer, M

    2015-01-01

    NGC253 is the nearest spiral galaxy with a nuclear starburst which becomes the best candidate to study the relationship between starburst and AGN activity. However, this central region is veiled by large amounts of dust, and it has been so far unclear which is the true dynamical nucleus. The near infrared spectroscopy could be advantageous in order to shed light on the true nucleus identity. Using Flamingos-2 at Gemini South we have taken deep K-band spectra along the major axis and through the brightest infrared source. We present evidence showing that the brightest near infrared and mid infrared source in the central region, already known as radio source TH7 and so far considered just a stellar supercluster, in fact, presents various symptoms of a genuine galactic nucleus. Therefore, it should be considered a valid nucleus candidate. It is the most massive compact infrared object in the central region, located at 2.0" of the symmetry center of the galactic bar. Moreover, our data indicate that this object i...

  9. Nonequilibrium distribution functions of nucleons in relativistic nucleus-nucleus collisions

    CERN Document Server

    Anchishkin, D; Cleymans, J; 10.5488/CMP.16.13201

    2013-01-01

    The collision smearing of the nucleon momenta about their initial values during relativistic nucleus-nucleus collisions is investigated. To a certain degree, our model belongs to the transport type, and we investigate the evolution of the nucleon system created at a nucleus-nucleus collision. However, we parameterize this development by the number of collisions of every particle during evolution rather than by the time variable. It is assumed that the group of nucleons which leave the system after the same number of collisions can be joined in a particular statistical ensemble. The nucleon nonequilibrium distribution functions, which depend on a certain number of collisions of a nucleon before freeze-out, are derived.

  10. Study of -nucleus interaction through the formation of -nucleus bound state

    Indian Academy of Sciences (India)

    V Jha; B J Roy; A Chatterjee; H Machner

    2006-05-01

    The question of possible existence of -mesic nuclei is quite intriguing. Answer to this question will deeply enrich our understanding of -nucleus interaction which is not so well-understood. We review the experimental efforts for the search of -mesic nuclei and describe the physics motivation behind it. We present the description of an experiment for the search of -nucleus bound state using the GeV proton beam, currently being performed at COSY.

  11. Centrality Dependence of Flow in High-Energy Nucleus-Nucleus Collisions

    Institute of Scientific and Technical Information of China (English)

    杨红艳; 周代翠; 杨纯斌; 蔡勖

    2002-01-01

    Directed flow and elliptic flow of final state particles in high-energy nucleus-nucleus collisions in the EMU01 experiment have been studied. The dependences of directed flow and elliptic flow on incident energy and impact centrality of outgoing particles are presented. The results exhibit strong dependence of flow on centrality and energy. We also suggest a more reliable way to determine the event plane resolution here.

  12. Why do we have a caudate nucleus?

    Science.gov (United States)

    Villablanca, Jaime R

    2010-01-01

    In order to understand the physiological role of the caudate nucleus, we combine here our laboratory data on cats with reports of patients with selective damage to this nucleus. Cats with bilateral removal of the caudate nuclei showed a stereotyped behavior consisting of persistently approaching and then following a person, another cat, or any object, and attempting to contact the target. Simultaneously, the animals exhibited a friendly disposition and persistent docility together with purring and forelimbs treading/kneading. The magnitude and duration of this behavior was proportional to the extent of the removal reaching a maximum after ablations of 65% or more of the caudate tissue. These cats were hyperactive but they had lost the feline elegance of movements. Additional features of acaudate cats were: (1) postural and accuracy deficits (plus perseveration) in paw usage tasks including bar pressing for food reward; (2) cognitive and perceptual impairments on a T-maze battery of tasks and on the bar pressing tasks; (3) blockage or blunting of the species-specific behavioral response to a single injection of morphine; Unilateral caudate nucleus removal did not produce global behavioral effects, but only deficit in the contralateral paw contact placing reaction and paw usage/bar pressing. Moreover and surprisingly, we found hypertrophy of the ipsilateral caudate nucleus following prenatal focal neocortical removal. The findings in human were also behavioral (not neurological) and also occurred with unilateral caudate damage. The main manifestations consisted of loss of drive (apathy), obsessive-compulsive behavior, cognitive deficits, stimulus-bound perseverative behavior, and hyperactivity. Based on all of the above data we propose that the specific function of the caudate nucleus is to control approach-attachment behavior, ranging from plain approach to a target, to romantic love. This putative function would account well for the caudate involvement in the

  13. Transverse momentum spectra in high-energy nucleus-nucleus, proton-nucleus and proton-proton collisions

    Institute of Scientific and Technical Information of China (English)

    XIE Wen-Jie

    2011-01-01

    The transverse momentum distributions of final-state particles produced in nucleus-nucleus (AA),proton-nucleus (pA),and proton-proton (pp) collisions at high energies are investigated using a multisource ideal gas model.Our calculated results show that the contribution of hard emission can be neglected in the study of transverse momentum spectra of charged pions and kaons produced in Cu-Cu collisions at (√SNN)=22.5 GeV.And if we consider the contribution of hard emission,the transverse momentum spectra of p and (P) produced in Cu-Cu collisions at (√SNN)=22.5 GeV,KsO produced in Pb-Pb collisions at 158 A GeV,J/ψ particles produced in p-Pb collisions at 400 GeV and π+,K+,p produced in proton-proton collisions at (√S)=200 GeV,can be described by the model,especially in the tail part of spectra.

  14. Rutherford, Radioactivity, and the Atomic Nucleus

    CERN Document Server

    Kragh, Helge

    2012-01-01

    Modern atomic and nuclear physics took its start in the early part of the twentieth century, to a large extent based upon experimental investigations of radioactive phenomena. Foremost among the pioneers of the new kind of physics was Ernest Rutherford, who made fundamental contributions to the structure of matter for more than three decades and, in addition, founded important research schools in Manchester and Cambridge. This paper reviews the most important aspects of Rutherford's scientific work in the period from about 1900 to 1920, and it also refers to some of his last experiments of the 1930s. The emphasis is on his theory of radioactive disintegration (1902), the discovery of the atomic nucleus (1911), and the first artificially produced element transformation (1919). Following the transmutation experiments, Rutherford developed elaborate models of the atomic nucleus, but these turned out to be unsuccessful. Other subjects could be included, but the three mentioned are undoubtedly those of the greates...

  15. Correlations in neutrino-nucleus scattering

    CERN Document Server

    Van Cuyck, Tom; Jachowicz, Natalie; González-Jiménez, Raul; Martini, Marco; Ryckebusch, Jan; Van Dessel, Nils

    2016-01-01

    We present a detailed study of charged-current quasielastic neutrino-nucleus scattering and of the influence of correlations on one- and two-nucleon knockout processes. The quasielastic neutrino-nucleus scattering cross sections, including the influence of long-range correlations, are evaluated within a continuum random phase approximation approach. The short-range correlation formalism is implemented in the impulse approximation by shifting the complexity induced by the correlations from the wave functions to the operators. The model is validated by confronting $(e,e^\\prime)$ cross-section predictions with electron scattering data in the kinematic region where the quasielastic channel is expected to dominate. Further, the $^{12}$C$(\

  16. Single pion production in neutrino nucleus scattering

    CERN Document Server

    Hernández, E; Vacas, M J Vicente

    2013-01-01

    We study one pion production in both charged and neutral current neutrino nucleus scattering for neutrino energies below 2 GeV. We use a theoretical model for one pion production at the nucleon level that we correct for medium effects. The results are incorporated into a cascade program that apart from production also includes the pion final state interaction inside the nucleus. Besides, in some specific channels coherent pion production is also possible and we evaluate its contribution as well. Our results for total and differential cross sections are compared with recent data from the MiniBooNE Collaboration. The model provides an overall acceptable description of data, better for NC than for CC channels, although theory is systematically below data. Differential cross sections, folded with the full neutrino flux, show that most of the missing pions lie on the forward direction and at high energies.

  17. Coherency in Neutrino-Nucleus Elastic Scattering

    CERN Document Server

    Kerman, S; Deniz, M; Wong, H T; Chen, J -W; Li, H B; Lin, S T; Liu, C -P; Yue, Q

    2016-01-01

    Neutrino-nucleus elastic scattering provides a unique laboratory to study the quantum mechanical coherency effects in electroweak interactions, towards which several experimental programs are being actively pursued. We report results of our quantitative studies on the transitions towards decoherency. A parameter ($\\alpha$) is identified to describe the degree of coherency, and its variations with incoming neutrino energy, detector threshold and target nucleus are studied. The ranges of $\\alpha$ which can be probed with realistic neutrino experiments are derived, indicating complementarity between projects with different sources and targets. Uncertainties in nuclear physics and in $\\alpha$ would constrain sensitivities in probing physics beyond the standard model. The maximum neutrino energies corresponding to $\\alpha$>0.95 are derived.

  18. Protein quality control in the nucleus

    DEFF Research Database (Denmark)

    Nielsen, Sofie V.; Poulsen, Esben Guldahl; Rebula, Caio A.

    2014-01-01

    to aggregate, cells have evolved several elaborate quality control systems to deal with these potentially toxic proteins. First, various molecular chaperones will seize the misfolded protein and either attempt to refold the protein or target it for degradation via the ubiquitin-proteasome system...... to be particularly active in protein quality control. Thus, specific ubiquitin-protein ligases located in the nucleus, target not only misfolded nuclear proteins, but also various misfolded cytosolic proteins which are transported to the nucleus prior to their degradation. In comparison, much less is known about...... these mechanisms in mammalian cells. Here we highlight recent advances in our understanding of nuclear protein quality control, in particular regarding substrate recognition and proteasomal degradation....

  19. Neutrino-nucleus reactions in supernovae

    Science.gov (United States)

    Dzhioev, Alan A.; Vdovin, A. I.

    2016-01-01

    We study thermal effects on neutrino-nucleus reactions occurring under supernova conditions. The approach we use is based on the QRPA extended to finite temperature by the thermofield dynamics formalism. For the relevant supernova conditions we calculate inelastic neutrino scattering and neutrino absorption cross sections for two sample nuclei, 56Fe and 82Ge. In addition, we apply the approach to examine the rate of neutrino-antineutrino pair emission by hot nuclei.

  20. Neutrino-nucleus reactions in supernovae

    Directory of Open Access Journals (Sweden)

    Dzhioev Alan A.

    2016-01-01

    Full Text Available We study thermal effects on neutrino-nucleus reactions occurring under supernova conditions. The approach we use is based on the QRPA extended to finite temperature by the thermofield dynamics formalism. For the relevant supernova conditions we calculate inelastic neutrino scattering and neutrino absorption cross sections for two sample nuclei, 56Fe and 82Ge. In addition, we apply the approach to examine the rate of neutrino-antineutrino pair emission by hot nuclei.

  1. Theoretical highlights of neutrino-nucleus interactions

    CERN Document Server

    Alvarez-Ruso, Luis

    2009-01-01

    The recent theoretical developments in the field of neutrino-nucleus interactions in the few-GeV region are reviewed based on the presentations made at the NuInt09 Workshop. The topics of electron scattering and its connections with neutrino interactions, neutrino induced quasielastic scattering and pion production (coherent and incoherent) are covered, with special emphasis on the challenges that arise in the comparison with new experimental data.

  2. Neutrino-nucleus CCQE-like scattering

    CERN Document Server

    Nieves, J; Simo, I Ruiz; Sanchez, F; Vacas, M J Vicente

    2014-01-01

    RPA correlations, spectral function and 2p2h (multi-nucleon) effects on charged-current neutrino-nucleus reactions without emitted pions are discussed. We pay attention to the influence of RPA and multi-nucleon mechanisms on the MiniBooNE and MINERvA flux folded differential cross sections, the MiniBooNE flux unfolded total cross section and the neutrino energy reconstruction.

  3. Development of a Mobile Ice Nucleus Counter

    Energy Technology Data Exchange (ETDEWEB)

    Kok, Gregory [Droplet Measurement Technologies, Boulder, CO (United States); Kulkarni, Gourihar [Droplet Measurement Technologies, Boulder, CO (United States)

    2014-07-10

    An ice nucleus counter has been constructed. The instrument uses built-in refrigeration systems for wall cooling. A cascade refrigeration system will allow the cold wall to operate as low as -70°C, and a single stage system can operate the warm wall at -45C. A unique optical particle counter has been constructed using polarization detection of the scattered light. This allows differentiation of the particles exiting the chamber to determine if they are ice or liquid.

  4. Development of a Mobile Ice Nucleus Counter

    Energy Technology Data Exchange (ETDEWEB)

    Kok, Gregory; Kulkarni, Gourihar

    2014-07-10

    An ice nucleus counter has been constructed. The instrument uses built-in refrigeration systems for wall cooling. A cascade refrigeration system will allow the cold wall to operate as low as -70 deg C, and a single stage system can operate the warm wall at -45 deg C. A unique optical particle counter has been constructed using polarization detection of the scattered light. This allows differentiation of the particles exiting the chamber to determine if they are ice or liquid.

  5. Comet nucleus and asteroid sample return missions

    Science.gov (United States)

    1992-01-01

    Three Advanced Design Projects have been completed this academic year at Penn State. At the beginning of the fall semester the students were organized into eight groups and given their choice of either a comet nucleus or an asteroid sample return mission. Once a mission had been chosen, the students developed conceptual designs. These were evaluated at the end of the fall semester and combined into three separate mission plans, including a comet nucleus same return (CNSR), a single asteroid sample return (SASR), and a multiple asteroid sample return (MASR). To facilitate the work required for each mission, the class was reorganized in the spring semester by combining groups to form three mission teams. An integration team consisting of two members from each group was formed for each mission so that communication and information exchange would be easier among the groups. The types of projects designed by the students evolved from numerous discussions with Penn State faculty and mission planners at the Johnson Space Center Human/Robotic Spacecraft Office. Robotic sample return missions are widely considered valuable precursors to manned missions in that they can provide details about a site's environment and scientific value. For example, a sample return from an asteroid might reveal valuable resources that, once mined, could be utilized for propulsion. These missions are also more adaptable when considering the risk to humans visiting unknown and potentially dangerous locations, such as a comet nucleus.

  6. Struktura i prediktori samoprocjene kreativnosti kod srednjoškolaca

    OpenAIRE

    Ljubotina, Damir; Juničić, Nataša; VLAHOVIĆ ŠTETIĆ, Vesna

    2015-01-01

    En esta investigación fue examinada la estructura de autoevaluaciones de la creatividad y de la conducta creativa y su conexión con los factores cognitivos, conativos y ambientales. Además, fue examinada la relación que estas variables tienen con el rendimiento escolar general. En la muestra de 255 estudiantes de secundaria se aplicaron el Cuestionario sobre la autoevaluación de la conducta creativa, el Cuestionario sobre la autoevaluación de creatividad, la Batería de pruebas de pensamiento ...

  7. Oscillations of moments in high-energy nucleus-nucleus collisions

    Institute of Scientific and Technical Information of China (English)

    杨红艳; 周代翠; 钱琬燕; 王晓荣

    2001-01-01

    The definitions of density function and moment of multiplicity distribution are introduced,and the method of moment analysis in e+ e- and proton-proton (pp) interactions is extended into nu-cleus-nucleus (AA) interactions. We analyze the data for relativistic nucleus-nucleus collisions and cal-culate the values of Hq for charged particle multiplicity distributions, by which we study systematically the dependences of Hq on incident energy, mass of colliding system, pseudorapidity interval, centrality and truncation of multiplicity. We compare the oscillation structures induced by e + e-, pp and AA inter-actions, and the comparison and analysis are carried out between experimental data and QCD predic-tion. The latest results are given in this paper.

  8. Transverse energy distributions in nucleus-nucleus collisions at 200 GeV/nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Baglin, C.; Baldisseri, A.; Bussiere, A.; Guillaud, J.P.; Kossakowski, R.; Liaud, P.; Staley, F. (Institut National de Physique Nucleaire et de Physique des Particules, 74 - Annecy-le-Vieux (France). Lab. de Physique des Particules); Baldit, A.; Castor, J.; Chambon, T.; Devaux, A.; Fargeix, J.; Felgeyrolles, X.; Force, P.; Fredj, L.; Landaud, G.; Vazeille, F. (Institut National de Physique Nucleaire et de Physique des Particules, 63 - Clermont-Ferrand (France). Lab. de Physique Corpusculaire Clermont-Ferrand-2 Univ., 63 - Aubiere (France)); Sonderegger, P. (European Organization for Nuclear Research, Geneva (Switzerland)); Abreu, M.C.; Bordalo, P.; Ferreira, R.; Gago, J.M.; Lourenco, C.; Peralta, L.; Pimenta, M.; Ramos, S.; Silva, S.; Varela, J. (LIP, Lisbon (Portugal)); Gerschel, C.; Jouan, D.; Papillon, S.; Tarrago, X. (Institut National de Physique Nucleaire et de Physique des Particules, 91 - Orsay (France). Inst. de Physique Nucleaire Paris-11 Univ., 91 - Orsay (France)); Bus; NA38 Collaboration

    1990-11-22

    The transverse energy E{sub T} distributions of nucleus-nucleus collisions are studied in the framework of a simple geometrical model. The distributions for inclusive production of J/{psi} and muon pairs in the mass continuum are analyzed. The shape of the E{sub T} distribution of the continuum agrees with the model. The previously observed decrease of the ratio (J/{psi})/continuum with increasing E{sub T} is due to the behavior of the J/{psi}. (orig.).

  9. Aspects of Coulomb dissociation and interference in peripheral nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Nystrand, Joakim; Baltz, Anthony; Klein, Spencer R.

    2001-10-21

    Coherent vector meson production in peripheral nucleus-nucleus collisions is discussed. These interactions may occur for impact parameters much larger than the sum of the nuclear radii. Since the vector meson production is always localized to one of the nuclei, the system acts as a two-source interferometer in the transverse plane. By tagging the outgoing nuclei for Coulomb dissociation it is possible to obtain a measure of the impact parameter and thus the source separation in the interferometer. This is of particular interest since the life-time of the vector mesons are generally much shorter than the impact parameters of the collisions.

  10. Jet tomography of high-energy nucleus-nucleus collisions at next-to-leading order

    Energy Technology Data Exchange (ETDEWEB)

    Vitev, Ivan [Los Alamos National Laboratory; Zhang, Ben - Wei [Los Alamos National Laboratory

    2009-01-01

    We demonstrate that jet observables are highly sensitive to the characteristics of the vacuum and the in-medium QCD parton showers and propose techniques that exploit this sensitivity to constrain the mechanism of quark and gluon energy loss in strongly-interacting plasmas. As a first example, we calculate the inclusive jet cross section in high-energy nucleus-nucleus collisions to {Omicron}({alpha}{sub s}{sup 3}). Theoretical predictions for the medium-induced jet broadening and the suppression of the jet production rate due to cold and hot nuclear matter effects in Au+Au and Cu+Cu reactions at RHIC are presented.

  11. Azimuthal correlations of hadrons and fragments in nucleus-nucleus collisions

    Institute of Scientific and Technical Information of China (English)

    LI Hui-Ling

    2011-01-01

    Two-particle (two-fragment) azimuthal correlation functions are studied by using a simple formula which describes uniformly azimuthal distributions of final-state charged particles and nuclear fragments.This formula is obtained in the framework of a multi-source thermal model (or multi-source ideal gas model).The calculated results are compared and found to be in agreement with the experimental data of charged hadrons and nuclear fragments in nucleus-nucleus collisions at intermediate and high energies.

  12. The effect of the relative nuclear size on the nucleus-nucleus interactions

    Science.gov (United States)

    Erofeeva, I. N.; Murzin, V. S.; Sivoklokov, S. Y.; Smirnova, L. N.

    1985-01-01

    The experimental data on the interactions of light nuclei (d, He(4), C(12)) at the momentum 4.2 GeV/cA with the carbon nuclei were taken in the 2-m propane bubble chamber. The distributions in the number of interacting nucleons, the spectra of protons, the mean energies of secondary pions and protons, the mean fractions of energy transferred to the pion and nucleon components are presented. The results of the investigation of the mechanism of nucleus-nucleus interactions can be used to calculate the nuclear cascades in the atmosphere.

  13. Electromagnetic processes in nucleus-nucleus collisions relating to space radiation research

    Science.gov (United States)

    Norbury, John W.

    1992-01-01

    Most of the papers within this report deal with electromagnetic processes in nucleus-nucleus collisions which are of concern in the space radiation program. In particular, the removal of one and two nucleons via both electromagnetic and strong interaction processes has been extensively investigated. The theory of relativistic Coulomb fission has also been developed. Several papers on quark models also appear. Finally, note that the theoretical methods developed in this work have been directly applied to the task of radiation protection of astronauts. This has been done by parameterizing the theoretical formalism in such a fashion that it can be used in cosmic ray transport codes.

  14. 35Cl NQR spectra of certain chlorine-containing chromium compounds

    Science.gov (United States)

    Kuznetsov, S. I.; Bryukhova, E. V.; Semin, G. K.

    2015-03-01

    The coordination of chlorobenzene to Cr(CO)3 and ClC6H5Cr+ fragments is shown to result in a considerable rise in the NQR frequency of chlorine atoms. The field constant in (chlorobenzene)chromium tricarbonyl was found to grow markedly, relative to pure chlorobenzene.

  15. Recent results on (anti)nucleus and (anti)hyperon production in nucleus-nucleus collisions at CERN SPS energies

    CERN Document Server

    Melkumov, G L; Anticic, T; Baatar, B; Barna, D; Bartke, J; Betev, L; Bialkowska, H; Blume, C; Boimska, B; Botje, M; Bracinik, J; Bramm, R; Buncic, P; Cerny, V; Christakoglou, P; Chung, P; Chvala, O; Cramer, J G; Csató, P; Dinkelaker, P; Eckardt, V; Flierl, D; Fodor, Z; Foka, P; Friese, V; Gál, J; Gazdzicki, M; Genchev, V; Georgopoulos, G; Grebieszkow, K; Hegyi, S; Höhne, C; Kadija, K; Karev, A; Kikola, D; Gladysz-Dziadus, E; Kliemant, M; Kniege, S; Kolesnikov, V I; Kornas, E; Korus, R; Kowalski, M; Kraus, I; Kreps, M; Laszlo, A; Lacey, R; Van Leeuwen, M; Lvai, P; Litov, L; Lungwitz, B; Makariev, M; Malakhov, A I; Mateev, M; Melkumov, G L; Mischke, A; Mitrovski, M; Molnár, J; Mrówczynski, S; Nicolic, V; Pálla, G; Panagiotou, A D; Panayotov, D; Petridis, A; Peryt, W; Pikna, M; Pluta, J; Prindle, D; Pühlhofer, F; Renfordt, R; Roland, C; Roland5, G; Rybczynski, M; Rybicki, A; Sandoval, A; Schmitz, N; Schuster, T; Siklér, F; Sitár, B; Skrzypczak, E; Slodkowski, M; Stefanek, G; Stock, R; Seyboth, P; Strabel, C; Ströbele, H; Susa, T; Szentpetery, I; Sziklai, J; Szuba, M; Szymanski, P; Trubnikov, V; Varga, D; Vassiliou, M; Veres, G I; Vesztergombi, G; Vranic, D; Wlodarczyk, Z; Wojtaszek11, A; Yoo, I K; Zimnyi, J; Wetzler, A

    2007-01-01

    The NA49 experiment has collected comprehensive data on particle production in nucleus-nucleus collisions over the whole SPS beam energies range, the critical energy domain where the expected phase transition to a deconfined phase is expected to occur. The latest results from Pb+Pb collisions between 20$A$ GeV and 158$A$ GeV on baryon stopping and light nuclei production as well as those for strange hyperons are presented. The measured data on $p$, $\\bar{p}$, $\\Lambda$, $\\bar{\\Lambda}$, $\\Xi^-$ and $\\bar{\\Xi}^+$ production were used to evaluate the rapidity distributions of net-baryons at SPS energies and to compare with the results from the AGS and the RHIC for central Pb+Pb (Au+Au) collisions. The dependence of the yield ratios and the inverse slope parameter of the $m_t$ spectra on the collision energy and centrality, and the mass number of the produced nuclei $^3He$, $t$, $d$ and $\\bar{d}$ are discussed within coalescence and statistical approaches. Analysis of the total multiplicity exhibits remarkable a...

  16. Contemporary models of the atomic nucleus

    CERN Document Server

    Nemirovskii, P E

    2013-01-01

    Contemporary Models of the Atomic Nucleus discusses nuclear structure and properties, expounding contemporary theoretical concepts of the low-energy nuclear processes underlying in nuclear models. This book focuses on subjects such as the optical nuclear model, unified or collective model, and deuteron stripping reaction. Other topics discussed include the basic nuclear properties; shell model; theoretical analysis of the shell model; and radiative transitions and alpha-decay. The deuteron theory and the liquid drop nuclear model with its application to fission theory are also mentioned, but o

  17. A thalamic input to the nucleus accumbens mediates opiate dependence.

    Science.gov (United States)

    Zhu, Yingjie; Wienecke, Carl F R; Nachtrab, Gregory; Chen, Xiaoke

    2016-02-11

    Chronic opiate use induces opiate dependence, which is characterized by extremely unpleasant physical and emotional feelings after drug use is terminated. Both the rewarding effects of a drug and the desire to avoid withdrawal symptoms motivate continued drug use, and the nucleus accumbens is important for orchestrating both processes. While multiple inputs to the nucleus accumbens regulate reward, little is known about the nucleus accumbens circuitry underlying withdrawal. Here we identify the paraventricular nucleus of the thalamus as a prominent input to the nucleus accumbens mediating the expression of opiate-withdrawal-induced physical signs and aversive memory. Activity in the paraventricular nucleus of the thalamus to nucleus accumbens pathway is necessary and sufficient to mediate behavioural aversion. Selectively silencing this pathway abolishes aversive symptoms in two different mouse models of opiate withdrawal. Chronic morphine exposure selectively potentiates excitatory transmission between the paraventricular nucleus of the thalamus and D2-receptor-expressing medium spiny neurons via synaptic insertion of GluA2-lacking AMPA receptors. Notably, in vivo optogenetic depotentiation restores normal transmission at these synapses and robustly suppresses morphine withdrawal symptoms. This links morphine-evoked pathway- and cell-type-specific plasticity in the paraventricular nucleus of the thalamus to nucleus accumbens circuit to opiate dependence, and suggests that reprogramming this circuit holds promise for treating opiate addiction.

  18. Ventromedial arcuate nucleus communicates peripheral metabolic information to the suprachiasmatic nucleus.

    NARCIS (Netherlands)

    Yi, C.-X.; Vliet, J. van der; Dai, J.; Yin, G.; Ru, L.; Buijs, R.M.

    2006-01-01

    The arcuate nucleus (ARC) is crucial for the maintenance of energy homeostasis as an integrator of long- and short-term hunger and satiety signals. The expression of receptors for metabolic hormones, such as insulin, leptin, and ghrelin, allows ARC to sense information from the periphery and signal

  19. Experimental study of collective flow phenomena in high-energy nucleus-nucleus collisions

    CERN Document Server

    Chkhaidze, L V; Kharkhelauri, L L

    2002-01-01

    The results of the experimental study of collective flow phenomena, such as the sideward and elliptic flow of nuclear matter, discovered during the last 10-15 years in high-energy nucleus-nucleus collisions are presented in this review. Sideward (often termed directed) and elliptic flows have been observed for protons, antiprotons, light nuclei, pions, kaons, and lambdas emitted in nucleus-nucleus collisions at 0.1-1.8 GeV/nucleon of LBL Bevalac and GSI/SIS by Plastic-Ball, Streamer Chamber, EOS-NPC, FOPI, LAND, TAPS, and KAOS collaborations; at 2-4 GeV/nucleon of Dubna JINR by SKM-200-GIBS, Propane Buble Chamber, and Emulsion Chamber collaborations; at 2-14 GeV/nucleon of BNL AGS, by the E877, E895, and E917 collaborations; and at 60 and 200 GeV/nucleon of CERN SPS, by the WA98 and NA49 collaborations and more recently by the STAR at RHIC BNL. In the review, the results of the SKM-200-GIBS collaboration of JINR are presented and compared with the results of different experiments by Bevalac, GSI/SIS, BNL, and...

  20. 5-hydroxytryptamine-mediated apnea caused by the habenular nucleus

    Institute of Scientific and Technical Information of China (English)

    Min Wang; Weihong Lin; Jinghua Wang; Min Huang; Chunyong Wang; Mingxian Li; Shao Wang

    2011-01-01

    5-hydroxytryptamine contributes to the control of activities of the dilator muscle in the upper respiratory tract, and is derived from the raphe nuclei, in which the habenular nucleus exerts a sustained inhibitory effect. In the present study, respiratory motion curve of the genioglossus muscle and peripheral 5-hydroxytryptamine changes were observed following L-glutamate stimulation of the habenular nucleus of adult Wistar rats. Results showed that the rats had apnea and decreased plasma 5-hydroxytryptamine content after the neurons in habenular nucleus were excited. Genioglossus muscle electromyogram amplitude and integral were significantly reduced. The genioglossus myoelectric activity and respiratory motion curve were similar to obstructive sleep apnea syndrome, thus confirming that the habenular nucleus is the key nucleus involved in the pathogenesis of obstructive sleep apnea syndrome, and is the primary regulated center in the raphe nuclei. Stimulation of the habenular nucleus may suppress 5-hydroxytryptamine release and result in apnea, which is similar to obstructive sleep apnea syndrome.

  1. Caudal topographic nucleus isthmi and the rostral nontopographic nucleus isthmi in the turtle, Pseudemys scripta.

    Science.gov (United States)

    Sereno, M I; Ulinski, P S

    1987-07-15

    Isthmotectal projections in turtles were examined by making serial section reconstructions of axonal and dendritic arborizations that were anterogradely or retrogradely filled with HRP. Two prominent tectal-recipient isthmic nuclei--the caudal magnocellular nucleus isthmi (Imc) and the rostral magnocellular nucleus isthmi (Imr)--exhibited strikingly different patterns of organization. Imc cells have flattened, bipolar dendritic fields that cover a few percent of the area of the cell plate constituting the nucleus and they project topographically to the ipsilateral tectum without local axon branches. The topography was examined explicitly at the single-cell level by using cases with two injections at widely separated tectal loci. Each Imc axon terminates as a compact swarm of several thousand boutons placed mainly in the upper central gray and superficial gray layers. One Imc terminal spans less that 1% of the tectal surface. Imr cells, by contrast, have large, sparsely branched dendritic fields overlapped by local axon collaterals while distally, their axons nontopographically innervate not only the deeper layers of the ipsilateral tectum but also ipsilateral Imc. Imr receives a nontopographic tectal input that contrasts with the topographic tectal input to Imc. Previous work on nucleus isthmi emphasized the role of the contralateral isthmotectal projection (which originates from a third isthmic nucleus in turtles) in mediating binocular interactions in the tectum. The present results on the two different but overlapping ipsilateral tecto-isthmo-tectal circuits set up by Imc and Imr are discussed in the light of physiological evidence for selective attention effects and local-global interactions in the tectum.

  2. Nucleus properties of P/Schwassmann-Wachmann 1

    Science.gov (United States)

    Meech, Karen J.; Belton, Michael J. S.; Mueller, Beatrice E. A.; Dicksion, Matthew W.; Li, Heide R.

    1993-01-01

    Time series photometric measurements are presented of Comet P/Schwassmann-Wachmann 1 at a heliocentric distance of 5.886 AU when the comet possessed an extensive coma. The light curve shows a modulation caused by the rotation of the nucleus. The rotation period is considerably shorter than the 5 day period found by Whipple (1980), and we find substantial evidence that the nucleus may be in a complex spin state characterized by two periods 14.0 and 32.3 hr. Models of the rate at which the rotational light curve range decreases as a function of the amount of coma in the aperture have determined that the projected maximum to minimum axis ratio of the comet is 2.6 and that the product of the albedo times the rotationally averaged nucleus radius size is 9.54 +/- 0.3 sq km. Assuming a minimum geometric albedo of pR = 0.04, the maximum projected average nucleus radius is 15.44 +/-0.2 km, which is only 44 percent of the size estimated by Roemer (1966). However, using the albedo determined by Cruikshank & Brown (1983) of p = 0.13, the nucleus radius is only RN = 8.6 +/-0.l km. Because of the unknown nucleus orientation, these will be upper limits to the nucleus size. It appears that the nucleus of P/Schwassmann-Wachmann 1 is not the large nucleus that it has been believed to be for nearly 40 yr.

  3. Delta-nucleus dynamics: proceedings of symposium

    Energy Technology Data Exchange (ETDEWEB)

    Lee, T.S.H.; Geesaman, D.F.; Schiffer, J.P. (eds.)

    1983-10-01

    The appreciation of the role in nuclear physics of the first excited state of the nucleon, the delta ..delta..(1232), has grown rapidly in the past decade. The delta resonance dominates nuclear reactions induced by intermediate energy pions, nucleons, and electromagnetic probes. It is also the most important non-nucleonic degree of freedom needed to resolve many fundamental problems encountered in the study of low-energy nuclear phenomena. Clearly, a new phase of nuclear physics has emerged and conventional thinking must be extended to account for this new dimension of nuclear dynamics. The most challenging problem we are facing is how a unified theory can be developed to describe ..delta..-nucleus dynamics at all energies. In exploring this new direction, it is important to have direct discussions among researchers with different viewpoints. Separate entries were prepared for the 49 papers presented. (WHK)

  4. Analysis of Returned Comet Nucleus Samples

    Science.gov (United States)

    Chang, Sherwood

    1997-12-01

    This volume contains abstracts that have been accepted by the Program Committee for presentation at the Workshop on Analysis of Returned Comet Nucleus Samples, held in Milpitas, California, January 16-18, 1989. Conveners are Sherwood Chang (NASA Ames Research Center) and Larry Nyquist (NASA Johnson Space Center). Program Committee members are Thomas Ahrens (ex-officio; California Institute of Technology), Lou Allamandola (NASA Ames Research Center), David Blake (NASA Ames Research Center), Donald Brownlee (University of Washington, Seattle), Theodore E. Bunch (NASA Ames Research Center), Humberto Campins (Planetary Science Institute), Jeff Cuzzi (NASA Ames Research Center), Eberhard Griin (Max-Plank-Institut fiir Kemphysik), Martha Hanner (Jet Propulsion Laboratory), Alan Harris (Jet Propulsion Laboratory), John Kerrid-e (University of Califomia, Los Angeles), Yves Langevin (University of Paris), Gerhard Schwehm (ESTEC), and Paul Weissman (Jet Propulsion Laboratory). Logistics and administrative support for the workshop were provided by the Lunar and Planetary Institute Projects Office.

  5. Jet energy loss and bulk parton collectivity in nucleus-nucleus collisions at RHIC

    Institute of Scientific and Technical Information of China (English)

    HUANG Huan-Zhong

    2009-01-01

    Nucleus-nucleus collisions at RHIC produce high temperature and high energy density matter which exhibits paxtonic degrees of freedom. We will discuss measurements of nuclear modification factors for light hadrons and non-photonic electrons from heavy quark decays, which reflect the flavor dependence of energy loss of high momentum partons traversing the dense QCD medium. The dense QCD medium responds to energy loss of high momentum patrons in a pattern consistent with that expected from a hydrodynamic fluid. The hadronization of bulk partonic matter exhibits collectivity with effective partonic degrees of freedom. Nuclear collisions at RHIC provide an intriguing environment, where many constituent quark ingredients are readily available for possible formation of exotic particles through quark coalescence or recombinations.

  6. Study of Strange and Multistrange Particles in Ultrarelativistic Nucleus-Nucleus Collisions

    CERN Multimedia

    Vande vyvre, P; Feofilov, G; Snoeys, W; Hetland, K F; Campbell, M; Klempt, W

    2002-01-01

    % NA57\\\\ \\\\ The goal of the experiment is to study the production of strange and multi-strange particles in nucleus-nucleus collisions. This study was initiated at the OMEGA spectrometer, where three ion experiments have been performed: WA85 (S-W and p-W collisions at 200 A GeV/c), WA94 (S-S and p-S collisions at 200 A GeV/c) and WA97 (Pb-Pb, p-Pb and p-Be collisions at 160 A GeV/c).\\\\ \\\\ The experiment aims at extending the scope of WA97 by:\\\\ \\\\ - investigating the beam energy dependence of the enhancements of multi-strange particle production reported by the previous experiments, and by\\\\ \\\\\\\\ \\\\- measuring the yields of strange and multi-strange particles over an extended centrality range compared with the previous experiments.\\\\ \\\\ The apparatus consists mainly of silicon pixel detector planes.

  7. Heavy flavors in nucleus-nucleus collisions at RHIC and LHC

    Directory of Open Access Journals (Sweden)

    Nardi Marzia

    2014-04-01

    Full Text Available A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA collisions — addressing within a comprehensive framework the initial QQ¯$Q\\overline Q $ production, the propagation in the hot medium until decoupling and the final hadronization and decays — is presented. The propagation of the heavy quarks in the medium is described in a framework provided by the relativistic Langevin equation and the corresponding numerical results are compared to experimental data from RHIC and the LHC. In particular, outcomes for the nuclear modification factor RAA and for the elliptic flow υ2 of D/B mesons, heavy-flavor electrons and non-prompt J/ψ’s are displayed.

  8. CASTOR: Centauro and strange object research in nucleus-nucleus collisions at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Angelis, A.L.S.; Bartke, J.; Bogolyubsky, M.Yu.; Gadysz-Dziadus, E.; Kharlov, Yu.V.; Kurepin, A.B.; Maevskaya, A.I.; Mavromanolakis, G.; Panagiotou, A.D.; Sadovsky, S.A.; Stefanski, P.; Wodarczyk, Z

    2001-04-01

    We present a phenomenological model which describes the formation of a Centauro fireball in the baryon-rich projectile fragmentation region in nucleus-nucleus interactions in the upper atmosphere and at the LHC, and its decay to non-strange baryons and Strangelets. Strangelets are assimilated to the 'strongly penetrating component' frequently observed accompanying hadron-rich cosmic ray events. We describe the CASTOR subdetector for the ALICE experiment at the LHC. CASTOR will probe, in an event-by-event mode, the very forward, baryon-rich phase space 5.6 {<=} {eta} {<=} 7.2 in 5.5 x A TeV central Pb + Pb collisions. It will look for events with pronounced imbalance between hadronic and photonic content and for deeply penetrating objects. We present results of simulations for the response of the CASTOR calorimeter to the passage of Strangelets.

  9. CASTOR Centauro and Strange Object Research in nucleus-nucleus collisions at LHC

    CERN Document Server

    Angelis, Aris L S; Bartke, Jerzy; Chileev, K; Gladysz-Dziadus, E; Golubeva, M B; Guber, F F; Karavitcheva, T L; Kharlov, Yu V; Kurepin, A B; Mavromanolakis, G; Panagiotou, A D; Sadovsky, S A; Tiflov, V V; Wlodarczyk, Z

    2002-01-01

    We describe the CASTOR detector designed to probe the very forward, baryon-rich rapidity region in nucleus-nucleus collisions at the LHC. We present a phenomenological model describing the formation of a QGP fireball in a high baryochemical potential environment, and its subsequent decay into baryons and strangelets. The model explains Centauros and the long-penetrating component and makes predictions for the LHC. Simulations of Centauro-type events were done. To study the response of the apparatus to new effects different exotic species (DCC, Centauros, strangelets etc.) were passed through the deep calorimeter. The energy deposition pattern in the calorimeter appears to be a new clear signature of the QGP.

  10. CASTOR Centauro And STrange Object Research in nucleus-nucleus collisions at the LHC

    CERN Document Server

    Angelis, Aris L S; Bogolyubsky, M Yu; Gladysz-Dziadus, E; Kharlov, Yu V; Kurepin, A B; Maevskaya, A I; Mavromanolakis, G; Panagiotou, A D; Sadovsky, S A; Stefanski, P; Wiodarczyk, Z

    2001-01-01

    We present a phenomenological model which describes the formation of a Centauro fireball in the baryon-rich projectile fragmentation region in nucleus-nucleus interactions in the upper atmosphere and at the LHC, and its decay to non-strange baryons and Strangelets. Strangelets are assimilated to the "strongly penetrating component" frequently observed accompanying hadron-rich cosmic ray events. We describe the CASTOR subdetector for the ALICE experiment at the LHC. CASTOR will probe, in an event-by-event mode, the very forward, baryon-rich phase space 5.6< eta <7.2 in 5.5*A TeV central Pb+Pb collisions. It will look for events with pronounced imbalance between hadronic and photonic content and for deeply penetrating objects. We present results of simulations for the response of the CASTOR calorimeter to the passage of Strangelets. (15 refs).

  11. Experimental and phenomenological investigations of QCD matter in high-energy nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Andronic, Anton

    2014-07-15

    This thesis is heterogeneous, comprising experimental papers at low energies (SIS-18 at GSI) and at the LHC, papers on phenomenology of high-energy nucleus-nucleus collisions, and papers on detectors. The overview covers the experimental papers and those on phenomenology. I have chosen to write it in a general manner, intended to be accessible to non-experts. It emphasizes recent measurements and their understanding at the LHC. The detector papers, which address many principle aspects of gaseous detectors, are summarized and placed in context in the review I co-wrote and which closes the stack. The detector papers included here are the outcome of an R and D program for the Transition Radiation Detector of ALICE.

  12. The Confined Hydrogen Atom with a Moving Nucleus

    Science.gov (United States)

    Fernandez, Francisco M.

    2010-01-01

    We study the hydrogen atom confined to a spherical box with impenetrable walls but, unlike earlier pedagogical articles on the subject, we assume that the nucleus also moves. We obtain the ground-state energy approximately by means of first-order perturbation theory and show that it is greater than that for the case in which the nucleus is clamped…

  13. A Frame Nucleus on a Two-side Prequantale

    Institute of Scientific and Technical Information of China (English)

    XUShao-xian; WANGShun-qin; MAFei-fei

    2004-01-01

    In this paper, a Frame nucleus and prime elements in a Prequantale are defined. The concrete structure of a Frame prequantic quotient is considered, and the relation between the half-prime element and the Frame nucleus in a two-side Prequantale are obtained.

  14. The subthalamic nucleus : Part I: Development, cytology, topography and connections

    NARCIS (Netherlands)

    Marani, Enrico; Heida, Tjitske; Lakke, Egbert A.J.F.; Usunoff, Kamen G.

    2008-01-01

    This monograph on the subthalamic nucleus accentuates in Part I the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections. The light and electron microscopical cytology concerns the open nucleus concept and the neuronal types p

  15. The Confined Hydrogen Atom with a Moving Nucleus

    Science.gov (United States)

    Fernandez, Francisco M.

    2010-01-01

    We study the hydrogen atom confined to a spherical box with impenetrable walls but, unlike earlier pedagogical articles on the subject, we assume that the nucleus also moves. We obtain the ground-state energy approximately by means of first-order perturbation theory and show that it is greater than that for the case in which the nucleus is clamped…

  16. Nucleus retroambiguus projections to the periaqueductal gray in the cat

    NARCIS (Netherlands)

    Klop, EM; Mouton, LJ; Holstege, G

    2002-01-01

    The nucleus retroambiguus (NRA) of the caudal medulla is a relay nucleus by which neurons of the mesencephalic periaqueductal gray (PAG) reach motoneurons of pharynx, larynx, soft palate, intercostal and abdominal muscles, and several muscles of the hindlimbs. These PAG-NRA-motoneuronal projections

  17. Glycine immunoreactivity of multipolar neurons in the ventral cochlear nucleus which project to the dorsal cochlear nucleus.

    Science.gov (United States)

    Doucet, J R; Ross, A T; Gillespie, M B; Ryugo, D K

    1999-06-14

    Certain distinct populations of neurons in the dorsal cochlear nucleus are inhibited by a neural source that is responsive to a wide range of acoustic frequencies. In this study, we examined the glycine immunoreactivity of two types of ventral cochlear nucleus neurons (planar and radiate) in the rat which project to the dorsal cochlear nucleus (DCN) and thus, might be responsible for this inhibition. Previously, we proposed that planar neurons provided a tonotopic and narrowly tuned input to the DCN, whereas radiate neurons provided a broadly tuned input and thus, were strong candidates as the source of broadband inhibition (Doucet and Ryugo [1997] J. Comp. Neurol. 385:245-264). We tested this idea by combining retrograde labeling and glycine immunohistochemical protocols. Planar and radiate neurons were first retrogradely labeled by injecting biotinylated dextran amine into a restricted region of the dorsal cochlear nucleus. The labeled cells were visualized using streptavidin conjugated to indocarbocyanine (Cy3), a fluorescent marker. Sections that contained planar or radiate neurons were then processed for glycine immunocytochemistry using diaminobenzidine as the chromogen. Immunostaining of planar neurons was light, comparable to that of excitatory neurons (pyramidal neurons in the DCN), whereas immunostaining of radiate neurons was dark, comparable to that of glycinergic neurons (cartwheel cells in the dorsal cochlear nucleus and principal cells in the medial nucleus of the trapezoid body). These results are consistent with the hypothesis that radiate neurons in the ventral cochlear nucleus subserve the wideband inhibition observed in the dorsal cochlear nucleus.

  18. Functional network inference of the suprachiasmatic nucleus.

    Science.gov (United States)

    Abel, John H; Meeker, Kirsten; Granados-Fuentes, Daniel; St John, Peter C; Wang, Thomas J; Bales, Benjamin B; Doyle, Francis J; Herzog, Erik D; Petzold, Linda R

    2016-04-19

    In the mammalian suprachiasmatic nucleus (SCN), noisy cellular oscillators communicate within a neuronal network to generate precise system-wide circadian rhythms. Although the intracellular genetic oscillator and intercellular biochemical coupling mechanisms have been examined previously, the network topology driving synchronization of the SCN has not been elucidated. This network has been particularly challenging to probe, due to its oscillatory components and slow coupling timescale. In this work, we investigated the SCN network at a single-cell resolution through a chemically induced desynchronization. We then inferred functional connections in the SCN by applying the maximal information coefficient statistic to bioluminescence reporter data from individual neurons while they resynchronized their circadian cycling. Our results demonstrate that the functional network of circadian cells associated with resynchronization has small-world characteristics, with a node degree distribution that is exponential. We show that hubs of this small-world network are preferentially located in the central SCN, with sparsely connected shells surrounding these cores. Finally, we used two computational models of circadian neurons to validate our predictions of network structure.

  19. Spontaneous fission of superheavy nucleus $^{286}$Fl

    CERN Document Server

    Poenaru, Dorin N

    2016-01-01

    The decimal logarithm of spontaneous fission half-life of the superheavy nucleus $^{286}$Fl experimentally determined is $\\log_{10} T_f^{exp} (s) = -0.632$. We present a method to calculate the half-life based on the cranking inertia and the deformation energy, functions of two independent surface coordinates, using the best asymmetric two center shell model. In the first stage we study the statics. At a given mass asymmetry up to about $\\eta=0.5$ the potential barrier has a two hump shape, but for larger $\\eta$ it has only one hump. The touching point deformation energy versus mass asymmetry shows the three minima, produced by shell effects, corresponding to three decay modes: spontaneous fission, cluster decay and $\\alpha$~decay. The least action trajectory is determined in the plane $(R,\\eta)$ where $R$ is the separation distance of the fission fragments and $\\eta$ is the mass asymmetry. We may find a sequence of several trajectories one of which gives the least action. The parametrization with two deforma...

  20. Inside a plant nucleus: discovering the proteins.

    Science.gov (United States)

    Petrovská, Beáta; Šebela, Marek; Doležel, Jaroslav

    2015-03-01

    Nuclear proteins are a vital component of eukaryotic cell nuclei and have a profound effect on the way in which genetic information is stored, expressed, replicated, repaired, and transmitted to daughter cells and progeny. Because of the plethora of functions, nuclear proteins represent the most abundant components of cell nuclei in all eukaryotes. However, while the plant genome is well understood at the DNA level, information on plant nuclear proteins remains scarce, perhaps with the exception of histones and a few other proteins. This lack of knowledge hampers efforts to understand how the plant genome is organized in the nucleus and how it functions. This review focuses on the current state of the art of the analysis of the plant nuclear proteome. Previous proteome studies have generally been designed to search for proteins involved in plant response to various forms of stress or to identify rather a modest number of proteins. Thus, there is a need for more comprehensive and systematic studies of proteins in the nuclei obtained at individual phases of the cell cycle, or isolated from various tissue types and stages of cell and tissue differentiation. All this in combination with protein structure, predicted function, and physical localization in 3D nuclear space could provide much needed progress in our understanding of the plant nuclear proteome and its role in plant genome organization and function.

  1. Observation of the antimatter helium-4 nucleus.

    Science.gov (United States)

    2011-05-19

    High-energy nuclear collisions create an energy density similar to that of the Universe microseconds after the Big Bang; in both cases, matter and antimatter are formed with comparable abundance. However, the relatively short-lived expansion in nuclear collisions allows antimatter to decouple quickly from matter, and avoid annihilation. Thus, a high-energy accelerator of heavy nuclei provides an efficient means of producing and studying antimatter. The antimatter helium-4 nucleus (4He), also known as the anti-α (α), consists of two antiprotons and two antineutrons (baryon number B = -4). It has not been observed previously, although the α-particle was identified a century ago by Rutherford and is present in cosmic radiation at the ten per cent level. Antimatter nuclei with B Collider (RHIC; ref. 6) in 10(9) recorded gold-on-gold (Au+Au) collisions at centre-of-mass energies of 200 GeV and 62 GeV per nucleon-nucleon pair. The yield is consistent with expectations from thermodynamic and coalescent nucleosynthesis models, providing an indication of the production rate of even heavier antimatter nuclei and a benchmark for possible future observations of 4He in cosmic radiation.

  2. Functional network inference of the suprachiasmatic nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Abel, John H.; Meeker, Kirsten; Granados-Fuentes, Daniel; St. John, Peter C.; Wang, Thomas J.; Bales, Benjamin B.; Doyle, Francis J.; Herzog, Erik D.; Petzold, Linda R.

    2016-04-04

    In the mammalian suprachiasmatic nucleus (SCN), noisy cellular oscillators communicate within a neuronal network to generate precise system-wide circadian rhythms. Although the intracellular genetic oscillator and intercellular biochemical coupling mechanisms have been examined previously, the network topology driving synchronization of the SCN has not been elucidated. This network has been particularly challenging to probe, due to its oscillatory components and slow coupling timescale. In this work, we investigated the SCN network at a single-cell resolution through a chemically induced desynchronization. We then inferred functional connections in the SCN by applying the maximal information coefficient statistic to bioluminescence reporter data from individual neurons while they resynchronized their circadian cycling. Our results demonstrate that the functional network of circadian cells associated with resynchronization has small-world characteristics, with a node degree distribution that is exponential. We show that hubs of this small-world network are preferentially located in the central SCN, with sparsely connected shells surrounding these cores. Finally, we used two computational models of circadian neurons to validate our predictions of network structure.

  3. Development of the human dorsal nucleus of the vagus.

    Science.gov (United States)

    Cheng, Gang; Zhu, Hua; Zhou, Xiangtian; Qu, Jia; Ashwell, K W S; Paxinos, G

    2008-01-01

    The dorsal nucleus of the vagus nerve plays an integral part in the control of visceral function. The aim of the present study was to correlate structural and chemical changes in the developing nucleus with available data concerning functional maturation of human viscera and reflexes. The fetal development (ages 9 to 26 weeks) of the human dorsal nucleus of the vagus nerve has been examined with the aid of Nissl staining and immunocytochemistry for calbindin and tyrosine hydroxylase. By 13 weeks, the dorsal vagal nucleus emerges as a distinct structure with at least two subnuclei visible in Nissl stained preparations. By 15 weeks, three subnuclei (dorsal intermediate, centrointermediate and ventrointermediate) were clearly discernible at the open medulla level with caudal and caudointermediate subnuclei visible at the level of the area postrema. All subnuclei known to exist in the adult were visible by 21 weeks and cytoarchitectonic differentiation of the nucleus was largely completed by 25 weeks. The adult distribution pattern of calbindin and tyrosine hydroxylase immunoreactive neurons was also largely completed by 21 weeks, although morphological differentiation of labeled neurons continued until the last age examined (26 weeks). The structural development of the dorsal nucleus of the vagus nerve appears to occur in parallel with functional maturation of the cardiovascular and gastric movements, which the nucleus controls.

  4. Nonthermal Fluctuations and Mechanics of the Active Cell Nucleus

    CERN Document Server

    Smith, K; Byrd, H; MacKintosh, F C; Kilfoil, M L

    2013-01-01

    We present direct measurements of fluctuations in the nucleus of yeast cells. While prior work has shown these fluctuations to be active and non-thermal in character, their origin and time dependence are not understood. We show that nuclear fluctuations can be quantitatively understood by uncorrelated, active force fluctuations driving a nuclear medium that is dominated by an uncondensed DNA solution, for which we perform rheological measurements on an in vitro model system under similar conditions to what is expected in the nucleus. We conclude that the eukaryotic nucleus of living cells is a nonequilibrium soft material whose fluctuations are actively driven, and are far from thermal in their time dependence.

  5. Quarkonium-nucleus bound states from lattice QCD

    Energy Technology Data Exchange (ETDEWEB)

    Beane, S.  R. [Univ. of Washington, Seattle, WA (United States); Chang, E. [Univ. of Washington, Seattle, WA (United States); Cohen, S.  D. [Univ. of Washington, Seattle, WA (United States); Detmold, W. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Lin, H. -W. [Univ. of Washington, Seattle, WA (United States); Orginos, K. [College of William and Mary, Williamsburg, VA (United States); Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Parreño, A. [Univ., de Barcelona, Marti Franques (Spain); Savage, M.  J. [Univ. of Washington, Seattle, WA (United States)

    2015-06-11

    Quarkonium-nucleus systems are composed of two interacting hadronic states without common valence quarks, which interact primarily through multi-gluon exchanges, realizing a color van der Waals force. We present lattice QCD calculations of the interactions of strange and charm quarkonia with light nuclei. Both the strangeonium-nucleus and charmonium-nucleus systems are found to be relatively deeply bound when the masses of the three light quarks are set equal to that of the physical strange quark. Extrapolation of these results to the physical light-quark masses suggests that the binding energy of charmonium to nuclear matter is B < 40 MeV.

  6. Nucleas (hadron) nucleus elastic scattering and geometrical picture

    Energy Technology Data Exchange (ETDEWEB)

    Aleem F.; Ali, S.; Saleem, M. [Univ. of the Punjab, Lahore (Pakistan)

    1995-08-01

    A comprehensive explanation of nucleus-nucleus and hadron-nucleus elastic scattering is elusive ever since the measurements of these reactions were made. By proposing energy dependent hadronic form factors for deuteron and alpha, in analogy to that of the proton as suggested by Chou and Yang recently, the authors have fitted all the available data for alpha-alpha and deuteron-deuteron elastic scattering. In order to further verify the validity of the proposed form factor, they have also fitted the data for proton-alpha and proton-deuteron elastic scattering. It is concluded that the hadronic matter is expanding with an increase in energy. 30 refs., 11 figs.

  7. The Acasta Gneiss - a Hadean cratonic nucleus

    Science.gov (United States)

    Sprung, P.; Scherer, E. E.; Maltese, A.; Bast, R.; Bleeker, W.; Mezger, K.

    2016-12-01

    The known terrestrial rock record lacks undisputed, chemically intact Hadean crust. Direct evidence from this eon has been restricted to zircon grains within younger rocks [1]. The Acasta Gneiss Complex (AGC; NT, CA) has yielded zircon with Hadean domains [e.g., 2,3], but the time at which AGC rocks became closed chemical systems is unclear [4,5]. Determining this `time of last disturbance' (tld) would provide a minimum protolith age, and is crucial for using radiogenic isotope compositions of bulk rocks to trace crust-mantle evolution. Recent studies mostly focused on the `low-strain' eastern AGC [e.g., 6, 7], which records an evolving, early-mid Archean cratonic nucleus [7]. We also studied the `high-strain' banded gneiss in the western AGC, which hosts >4 Ga zircon domains [2,3], too. Our focusing lay on adjoining, lithologically distinct bands [8] of two distinct chemical groups: A) Mafic, chondrite-normalized LaN/YbN ≦20, slightly HFSE- depleted, and B) TTG-like, LaN/YbN up to 145, markedly HFSE-depleted. Six adjacent bands yield a well-defined 4 Ga Sm-Nd isochron with a ɛNd4Ga of +2 and ɛHf4Ga values from +1 to +6. Within-band Sm-Nd and Lu-Hf systematics imply younger mineral re-equilibration [9]. We interpret the 4 Ga Sm-Nd isochron to date the physical juxtaposition of bands in the gneiss unit and to define tld among bands for elements less mobile and diffusive than Sm and Nd. Contrasting Sm-Nd results from the same unit [10] likely are due to sampling at too fine a scale. Digestion of metamict pre-tld zircon likely caused the scatter in Lu-Hf. Both decay systems hint at the existence of a possibly local, strongly depleted Hadean mantle domain. The TTG-like bands are 0.4 Gyr older than similar rocks in the `low-strain' eastern AGC [7]. The AGC was thus an evolved cratonic nucleus already at 4 Ga, possibly with a depleted lithospheric keel. [1] Cavosie et al. (2004) Prec. Res. 135, 251-279 [2] Bowring & Williams (1999) CMP 134, 3-16 [3] Iizuka et al

  8. Structural Description of Polyaromatic Nucleus in Residue

    Institute of Scientific and Technical Information of China (English)

    Zhang Huicheng; Yan Yongjie; Sun Wanfu; Wang Jifeng

    2007-01-01

    The proton nuclear magnetic resonance spectroscopy(1H-NMR),the synchronous fluorescence spectrometry(SFS)and the rutheniam ions catalyzed oxidation(RICO)method wen used to determine the chemical structure of polyaromatic nucleus in Oman residue fractions.The results of1H-NMR analyses showed that the average numbers of aromatic rings in the aromatics,resins and asphaltenes units were 3.2,5.6 and 8.2.respectively.SFS was used to investigate the distribution of aromatic tings in residue fractions,the main distribution range of aromatic rings in aromatics,resins and asphaltenes were 3-4 rings,3-5 rings and more than 5 tings,respectively.The aromatic network in residue fractions was oxidized to produce numerous carboxylic acids.The types and content of benzenepolycarboxylic acids,such as phthalic acid,benzenetricarboxylic acids,benzenetetracarbOxylic acids,benzenepentacarboxylic acid and benzenehexacarboxylic acid disclosed the condensed types of aromatic nuclei in the core.The biphenyl fraction(BIPH),the cata-condensed fraction(CATA),the peri-condensed fraction(PERI)and the condensed index(BCI)were calculated based on the benzenepolycarboxylic acids formed.The results implied that there was less biphenyl type structures in all residue fractions.The aromatics fraction was almost composed of the cata-condensed type system,and the asphaltenes fraction was wholly composed of the peri-condensed type system,while in the resins fraction co-existed the two types,herein the peri-condensed type Was predominant over the cata-condensed type.Based on the analytical results obtained in the study,the components-aromatics,resins and asphaltenes-were given the likely structural models.

  9. Nuclear mean field and double-folding model of the nucleus-nucleus optical potential

    CERN Document Server

    Khoa, Dao T; Loan, Doan Thi; Loc, Bui Minh

    2016-01-01

    Realistic density dependent CDM3Yn versions of the M3Y interaction have been used in an extended Hartree-Fock (HF) calculation of nuclear matter (NM), with the nucleon single-particle potential determined from the total NM energy based on the Hugenholtz-van Hove theorem that gives rise naturally to a rearrangement term (RT). Using the RT of the single-nucleon potential obtained exactly at different NM densities, the density- and energy dependence of the CDM3Yn interactions was modified to account properly for both the RT and observed energy dependence of the nucleon optical potential. Based on a local density approximation, the double-folding model of the nucleus-nucleus optical potential has been extended to take into account consistently the rearrangement effect and energy dependence of the nuclear mean-field potential, using the modified CDM3Yn interactions. The extended double-folding model was applied to study the elastic $^{12}$C+$^{12}$C and $^{16}$O+$^{12}$C scattering at the refractive energies, wher...

  10. Statistical Model of the Early Stage of nucleus-nucleus collisions with exact strangeness conservation

    CERN Document Server

    Poberezhnyuk, R V; Gorenstein, M I

    2015-01-01

    The Statistical Model of the Early Stage, SMES, describes a transition between confined and deconfined phases of strongly interacting matter created in nucleus-nucleus collisions. The model was formulated in the late 1990s for central Pb+Pb collisions at the CERN SPS energies. It predicted several signals of the transition (onset of deconfinement) which were later observed by the NA49 experiment. The grand canonical ensemble was used to calculate entropy and strangeness production. This approximation is valid for reactions with mean multiplicities of particles carrying conserved charges being significantly larger than one. Recent results of NA61/SHINE on hadron production in inelastic p+p interactions suggest that the deconfinement may also take place in these reactions. However, in this case mean multiplicity of particles with non-zero strange charge is smaller than one. Thus for the modeling of p+p interactions the exact strangeness conservation has to be implemented in the SMES. This extension of the SMES ...

  11. Heavy-flavor dynamics in nucleus-nucleus collisions: from RHIC to LHC

    CERN Document Server

    Monteno, M; Beraudo, A; De Pace, A; Molinari, A; Nardi, M; Prino, F

    2011-01-01

    The stochastic dynamics of c and b quarks in the fireball created in nucleus-nucleus collisions at RHIC and LHC is studied employing a relativistic Langevin equation, based on a picture of multiple uncorrelated random collisions with the medium. Heavy-quark transport coefficients are evaluated within a pQCD approach, with a proper HTL resummation of medium effects for soft scatterings. The Langevin equation is embedded in a multi-step setup developed to study heavy-flavor observables in pp and AA collisions, starting from a NLO pQCD calculation of initial heavy-quark yields, complemented in the nuclear case by shadowing corrections, k_T-broadening and nuclear geometry effects. Then, only for AA collisions, the Langevin equation is solved numerically in a background medium described by relativistic hydrodynamics. Finally, the propagated heavy quarks are made hadronize and decay into electrons. Results for the nuclear modification factor R_AA of heavy-flavor hadrons and electrons from their semi-leptonic decays...

  12. EOS: A time projection chamber for the study of nucleus-nucleus collisions at the Bevalac

    Energy Technology Data Exchange (ETDEWEB)

    Pugh, H.G.; Odyniec, G.; Rai, G.; Seidl, P.

    1986-12-01

    The conceptual design is presented for a detector to identify and measure (..delta..p/p approx. = 1%) most of the 200 or so mid-rapidity charged particles (p, d, t, /sup 3/He, /sup 4/He, ..pi../sup + -/, K/sup + -/) produced in each central nucleus-nucleus collision (Au + Au) at Bevalac energies, as well as K/sub 3//sup 0/ and ..lambda../sup 0/. The beam particles and heavy spectator fragments are excluded from the detection volume by means of a central vacuum pipe. Particle identification is achieved by a combination of dE/dx measurements in the TPC, and of time-of-flight measurements in a scintillator array. The TPC is single-ended and its end cap is entirely covered with cathode pads (about 25,000 pads and about 1000 anode wires). A non-uniform pad distribution is proposed to accommodate the high multiplicity of particles emitted at forward angles. The performance of the detector is assessed with regard to multihit capability, tracking, momentum resolution, particle identification, ..lambda../sup 0/ reconstruction, space charge effects, field non-uniformity, dynamic range, data acquisition rate, and data analysis rate. 72 refs., 48 figs., 11 tabs.

  13. Charm quarks as a probe of matter produced in relativistic nucleus-nucleus collisions

    Directory of Open Access Journals (Sweden)

    Ali Yasir

    2014-04-01

    Full Text Available Direct measurement of hadrons containing charm quark carries important information about the initial stage of the nucleus-nucleus collision at relativistic energies. The study of open charm in Pb-Pb collisions at SPS energies will be a powerful tool to investigate the production of heavy flavours and their interaction with the medium produced in such collisions. A feasibility study was initiated for the measurement of the D0 mesons (open charm by its two-body decay into pion and kaon in central Pb-Pb collision at SPS energies in NA61/SHINE experiment. To generate the physical input we used AMPT (A Multi Phase Transport Model event generator and employed GEANT4 application to describe particle transport through the NA61/SHINE experimental setup supplemented by a future vertex detector (VD that will allow for precise vertex reconstruction close to the primary interaction point. The results of the simulation shows that this measurement is feasible with a dedicated VD which allows the precise tracking close to the target.

  14. Formation and identification of Centauro and Strangelets in nucleus- nucleus collisions at the LHC

    CERN Document Server

    Angelis, Aris L S; Bogolyubsky, M Yu; Filippov, S N; Gladysz-Dziadus, E; Kharlov, Yu V; Kurepin, A B; Maevskaya, A I; Mavromanolakis, G; Panagiotou, A D; Sadovsky, S A; Stefanski, P; Wlodarczyk, Z

    1999-01-01

    We present a phenomenological model for the formation and decay of a cosmic ray Centauro fireball in the baryon-rich projectile fragmentation rapidity region in nucleus-nucleus interactions. Our model naturally incorporates the $9 possibility of strangelet formation, Strangelets being conjectured to be the "strongly penetrating component" observed in hadron-rich cosmic ray events. Based on this model we have performed Monte-Carlo simulations to study the $9 Centauro and strangelet dynamic and kinematic characteristics in central Pb+Pb collisions at LHC energies, as well as their identification by the detector system CASTOR. CASTOR is being developed for the ALICE heavy ion experiment at $9 the LHC and will probe the very forward pseudorapidity region 5.6

  15. Formation and identification of Centauro and strangelets in nucleus-nucleus collisions at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Angelis, A.L.S.; Bartke, J.; Bogolyubsky, M.Yu.; Filippov, S.N.; Gladysz-Dziadus, E.; Kharlov, Yu.V.; Kurepin, A.B.; Maevskaya, A.I.; Mavromanolakis, G.; Panagiotou, A.D.; Sadovsky, S.A.; Stefanski, P.; Wlodarczyk, Z

    1999-03-01

    We present a phenomenological model for the formation and decay of a cosmic ray Centauro fireball in the baryon-rich projectile fragmentation rapidity region in nucleus-nucleus interactions. Our model naturally incorporates the possibility of Strangelet formation, Strangelets being conjectured to be the 'strongly penetrating component' observed in hadron-rich cosmic ray events. Based on this model we have performed Monte-Carlo simulations to study the Centauro and Strangelet dynamic and kinematic characteristics in central Pb + Pb collisions at LHC energies, as well as their identification by the detector system CASTOR. CASTOR is being developed for the ALICE heavy ion experiment at the LHC and will probe the very forward pseudorapidity region 5.6 {<=} {eta} {<=} 7.2, characterized by very high baryon density. CASTOR is optimised to search for Centauro signatures and long penetrating objects. Simulations show that CASTOR is well able to distinguish events with abnormal values of E{sub em}/E{sub had} or N{sub {gamma}}/N{sub ch}. In addition simulations of the transition curves of Strangelets traversing the CASTOR calorimeter show long penetration and many-maxima structure such as observed in cosmic ray events.

  16. Quantitative analysis of the fusion cross sections using different microscopic nucleus-nucleus interactions

    Science.gov (United States)

    Adel, A.; Alharbi, T.

    2017-01-01

    The fusion cross sections for reactions involving medium and heavy nucleus-nucleus systems are investigated near and above the Coulomb barrier using the one-dimensional barrier penetration model. The microscopic nuclear interaction potential is computed by four methods, namely: the double-folding model based on a realistic density-dependent M3Y NN interaction with a finite-range exchange part, the Skyrme energy density functional in the semiclassical extended Thomas-Fermi approximation, the generalized Proximity potential, and the Akyüz-Winther interaction. The comparison between the calculated and the measured values of the fusion excitation functions indicates that the calculations of the DFM give quite satisfactory agreement with the experimental data, being much better than the other methods. New parameterized forms for the fusion barrier heights and positions are presented. Furthermore, the effects of deformation and orientation degrees of freedom on the distribution of the Coulomb barrier characteristics as well as the fusion cross sections are studied for the reactions 16 O + 70 Ge and 28 Si + 100 Mo. The calculated values of the total fusion cross sections are compared with coupled channel calculations using the code CCFULL and compared with the experimental data. Our results reveal that the inclusion of deformations and orientation degrees of freedom improves the comparison with the experimental data.

  17. Constraining in-medium nucleon-nucleon interactions via nucleus-nucleus reactions

    Science.gov (United States)

    Sammarruca, Francesca; White, Larz

    2010-11-01

    The nuclear equation of state is a broadly useful tool. Besides being the main input of stellar structure calculations, it allows a direct connection to the physics of nuclei. For instance, an energy functional (such as a mass formula), together with the energy/particle in nuclear matter, can be used to predict nuclear energies and radii [1]. The single-particle properties are also a key point to link infinite nuclear matter and actual nuclei. The parameters of the single-particle potential, in particular the effective mass, enter the calculations of, for instance, in-medium effective cross sections. From the well-known Glauber reaction theory, the total nucleus-nucleus reaction cross section is expressed in terms of the nuclear transparency, which, in turn, depends on the overlap of the nuclear density distributions and the elementary nucleon-nucleon (NN) cross sections. We explore the sensitivity of the reaction calculation to medium modifications of the NN cross sections to estimate the likelihood of constraining the latter through nuclear reactions. Ultimately, we wish to incorporate isospin asymmetry in the reaction model, having in mind connections with rare isotopes. [1] F. Sammarruca, arXiv:1002.00146 [nucl-th]; International Journal of Modern Physics, in press.

  18. Suprachiasmatic Nucleus Interaction with the Arcuate Nucleus; Essential for Organizing Physiological Rhythms

    Science.gov (United States)

    Guzmán-Ruiz, Mara

    2017-01-01

    Abstract The suprachiasmatic nucleus (SCN) is generally considered the master clock, independently driving all circadian rhythms. We recently demonstrated the SCN receives metabolic and cardiovascular feedback adeptly altering its neuronal activity. In the present study, we show that microcuts effectively removing SCN-arcuate nucleus (ARC) interconnectivity in Wistar rats result in a loss of rhythmicity in locomotor activity, corticosterone levels, and body temperature in constant dark (DD) conditions. Elimination of these reciprocal connections did not affect SCN clock gene rhythmicity but did cause the ARC to desynchronize. Moreover, unilateral SCN lesions with contralateral retrochiasmatic microcuts resulted in identical arrhythmicity, proving that for the expression of physiological rhythms this reciprocal SCN-ARC interaction is essential. The unaltered SCN c-Fos expression following glucose administration in disconnected animals as compared to a significant decrease in controls demonstrates the importance of the ARC as metabolic modulator of SCN neuronal activity. Together, these results indicate that the SCN is more than an autonomous clock, and forms an essential component of a larger network controlling homeostasis. The present novel findings illustrate how an imbalance between SCN and ARC communication through circadian disruption could be involved in the etiology of metabolic disorders. PMID:28374011

  19. Isotope Dependence of Superheavy Nucleus Formation Cross Section

    Institute of Scientific and Technical Information of China (English)

    LIU Zu-Hua; BAG Jing-Dong

    2006-01-01

    The dynamical process in the superheavy nucleus synthesis is studied on the basis of the two-dimensional Smolu-chowski equation. Special attention is paid to the isotope dependence of the cross section for the superheavy nucleus formation by means of making a comparison among the reaction systems of 54Fe + 204Pb, 56Fe + 206Pb, and 58Fe + 208Pb. It is found by this comparison that the formation cross section is very sensitive to the conditional saddle-point height and the neutron separation energy of the compound nucleus. Reaction systems with lower height of conditional saddle-point and smaller neutron separation energy are more favourable for the synthesis of the superheavy nucleus.

  20. Cytotoxicity of nucleus-targeting fluorescent gold nanoclusters

    Science.gov (United States)

    Zhao, Jing-Ya; Cui, Ran; Zhang, Zhi-Ling; Zhang, Mingxi; Xie, Zhi-Xiong; Pang, Dai-Wen

    2014-10-01

    Gold nanoclusters (AuNCs) with ultra small sizes and unique fluorescence properties have shown promising potential for imaging the nuclei of living cells. However, little is known regarding the potential cytotoxicity of AuNCs after they enter the cell nucleus. The aim of this study is to investigate whether and how nucleus-targeting AuNCs affect the normal functioning of cells. Highly stable, water-soluble and bright fluorescent Au25NCs (the core of each nanocluster is composed of 25 gold atoms) were synthesized. Specific targeting of Au25NCs to the cell nucleus was achieved by conjugating the TAT peptide to the Au25NCs. Cell viability, cell morphology, cell apoptosis/necrosis, reactive oxygen species (ROS) level and mitochondrial membrane potential examinations were performed on different cell lines exposed to the nucleus-targeting Au25NCs. We found that the nucleus-targeting Au25NCs caused cell apoptosis in a dose-dependent manner. A possible mechanism for the cytotoxicity of the nucleus-targeting Au25NCs was proposed as follows: the nucleus-targeting Au25NCs induce the production of ROS, resulting in the oxidative degradation of mitochondrial components, in turn leading to apoptosis via a mitochondrial damage pathway. This work facilitates a better understanding of the toxicity of AuNCs, especially nucleus-targeting AuNCs.Gold nanoclusters (AuNCs) with ultra small sizes and unique fluorescence properties have shown promising potential for imaging the nuclei of living cells. However, little is known regarding the potential cytotoxicity of AuNCs after they enter the cell nucleus. The aim of this study is to investigate whether and how nucleus-targeting AuNCs affect the normal functioning of cells. Highly stable, water-soluble and bright fluorescent Au25NCs (the core of each nanocluster is composed of 25 gold atoms) were synthesized. Specific targeting of Au25NCs to the cell nucleus was achieved by conjugating the TAT peptide to the Au25NCs. Cell viability, cell

  1. Nucleus management in manual small incision cataract surgery by phacosection

    Directory of Open Access Journals (Sweden)

    Ravindra M

    2009-01-01

    Full Text Available Nucleus management is critical in manual small incision cataract surgery (MSICS, as the integrity of the tunnel, endothelium and posterior capsule needs to be respected. Several techniques of nucleus management are in vogue, depending upon the specific technique of MSICS. Nucleus can be removed in toto or bisected or trisected into smaller segments. The pressure in the eye can be maintained at the desired level with the use of an anterior chamber maintainer or kept at atmospheric levels. In MSICS, unlike phacoemulsification, there is no need to limit the size of the tunnel or restrain the size of capsulorrhexis. Large well-structured tunnels and larger capsulorrhexis provide better control on the surgical maneuvers. Safety and simplicity of MSICS has made it extremely popular. The purpose of this article is to describe nucleus management by phacosection in MSICS.

  2. Low-energy antinucleon-nucleus interaction revisited

    Science.gov (United States)

    Friedman, E.

    2015-08-01

    Annihilation cross sections of antiprotons and antineutrons on the proton between 50 and 400 MeV/c show Coulomb focusing below 200 MeV/c and almost no charge-dependence above 200 MeV/c. Similar comparisons for heavier targets are not possible for lack of overlap between nuclear targets studied with and beams. Interpolating between -nucleus annihilation cross sections with the help of an optical potential to compare with -nucleus annihilation cross sections reveal unexpected features of Coulomb interactions in the latter. Direct comparisons between -nucleus and -nucleus annihilations at very low energies could be possible if cross sections are measured on the same targets and at the same energies as the available cross sections for . Such measurements may be feasible in the foreseeable future.

  3. The integrative role of the pedunculopontine nucleus in human gait.

    Science.gov (United States)

    Lau, Brian; Welter, Marie-Laure; Belaid, Hayat; Fernandez Vidal, Sara; Bardinet, Eric; Grabli, David; Karachi, Carine

    2015-05-01

    The brainstem pedunculopontine nucleus has a likely, although unclear, role in gait control, and is a potential deep brain stimulation target for treating resistant gait disorders. These disorders are a major therapeutic challenge for the ageing population, especially in Parkinson's disease where gait and balance disorders can become resistant to both dopaminergic medication and subthalamic nucleus stimulation. Here, we present electrophysiological evidence that the pedunculopontine and subthalamic nuclei are involved in distinct aspects of gait using a locomotor imagery task in 14 patients with Parkinson's disease undergoing surgery for the implantation of pedunculopontine or subthalamic nuclei deep brain stimulation electrodes. We performed electrophysiological recordings in two phases, once during surgery, and again several days after surgery in a subset of patients. The majority of pedunculopontine nucleus neurons (57%) recorded intrasurgically exhibited changes in activity related to different task components, with 29% modulated during visual stimulation, 41% modulated during voluntary hand movement, and 49% modulated during imaginary gait. Pedunculopontine nucleus local field potentials recorded post-surgically were modulated in the beta and gamma bands during visual and motor events, and we observed alpha and beta band synchronization that was sustained for the duration of imaginary gait and spatially localized within the pedunculopontine nucleus. In contrast, significantly fewer subthalamic nucleus neurons (27%) recorded intrasurgically were modulated during the locomotor imagery, with most increasing or decreasing activity phasically during the hand movement that initiated or terminated imaginary gait. Our data support the hypothesis that the pedunculopontine nucleus influences gait control in manners extending beyond simply driving pattern generation. In contrast, the subthalamic nucleus seems to control movement execution that is not likely to be gait

  4. Shell Correction at the Saddle Point for Superheavy Nucleus

    Institute of Scientific and Technical Information of China (English)

    张炜; 张时声; 张双全; 孟杰

    2003-01-01

    The potential energy surface for superheavy nucleus has been studied within the framework of the constrained relativistic mean field theory, and the shell correction energy as a function of deformation has been extracted by the Strutinsky shell correction procedure. Contrary to the usual expectation, the shell correction energy at the saddle point is too important to be neglected, and it has essential contribution to the fission barrier in superheavy nucleus.

  5. Colour, albedo and nucleus size of Halley's comet

    Science.gov (United States)

    Cruikshank, D. P.; Tholen, D. J.; Hartmann, W. K.

    1985-01-01

    Photometry of Halley's comet in the B, J, V, and K broadband filters during a time when the coma was very weak and presumed to contribute negligibly to the broadband photometry is reported. The V-J and J-K colors suggest that the color of the nucleus of Halley's comet is similar to that of the D-type asteroids, which in turn suggests that the surface of the nucleus has an albedo less than 0.1.

  6. Truncal ataxia from infarction involving the inferior olivary nucleus.

    Science.gov (United States)

    Park, Jae Hyun; Ryoo, Sookyung; Moon, So Young; Seo, Sand Won; Na, Duk L

    2012-08-01

    Truncal ataxia in medullary infarction may be caused by involvement of the lateral part of the medulla; however, truncal ataxia in infarction involving the inferior olivary nucleus (ION) has received comparatively little attention. We report a patient with truncal ataxia due to medial medullary infarction located in the ION. A lesion in the ION could produce a contralateral truncal ataxia due to increased inhibitory input to the contralesional vestibular nucleus from the contralesional flocculus.

  7. A FIBER APPARATUS IN THE NUCLEUS OF THE YEAST CELL

    Science.gov (United States)

    Robinow, C. F.; Marak, J.

    1966-01-01

    The structure and mode of division of the nucleus of budding yeast cells have been studied by phase-contrast microscopy during life and by ordinary microscopy after Helly fixation. The components of the nucleus were differentially stained by the Feulgen procedure, with Giemsa solution after hydrolysis, and with iron alum haematoxylin. New information was obtained in cells fixed in Helly's by directly staining them with 0.005% acid fuchsin in 1% acetic acid in water. Electron micrographs have been made of sections of cells that were first fixed with 3% glutaraldehyde, then divested of their walls with snail juice, and postfixed with osmium tetroxide. Light and electron microscopy have given concordant information about the organization of the yeast nucleus. A peripheral segment of the nucleus is occupied by relatively dense matter (the "peripheral cluster" of Mundkur) which is Feulgen negative. The greater part of the nucleus is filled with fine-grained Feulgen-positive matter of low density in which chromosomes could not be identified. Chromosomes become visible in this region under the light microscope at meiosis. In the chromatin lies a short fiber with strong affinity for acid fuchsin. The nucleus divides by elongation and constriction, and during this process the fiber becomes long and thin. Electron microscopy has resolved it into a bundle of dark-edged 150 to 180 A filaments which extends between "centriolar plaques" that are attached to the nuclear envelope. PMID:5331666

  8. Stopping powers and cross sections due to two-photon processes in relativistic nucleus-nucleus collisions

    Science.gov (United States)

    Cheung, Wang K.; Norbury, John W.

    1994-01-01

    The effects of electromagnetic-production processes due to two-photon exchange in nucleus-nucleus collisions are discussed. Feynman diagrams for two-photon exchange are evaluated using quantum electrodynamics. The total cross section and stopping power for projectile and target nuclei of identical charge are found to be significant for heavy nuclei above a few GeV per nucleon-incident energy.

  9. Coherent production of the long-lived pionium nP states in relativistic nucleus-nucleus collisions

    CERN Document Server

    Gevokyan, S

    2015-01-01

    The coherent production of the $nP$ states of the $\\pi^+\\pi^-$ atoms ($A_{2\\pi}$) in relativistic nucleus-nucleus collisions is considered as a possible source of the $A_{2\\pi}(nP)$ beam for the pionium Lamb-shift measurement. A general expression for estimation of the $A_{2\\pi}(nP)$ yields is derived in the framework of the equivalent photon approximation.

  10. The interfascicular trigeminal nucleus: a precerebellar nucleus in the mouse defined by retrograde neuronal tracing and genetic fate mapping.

    Science.gov (United States)

    Fu, Yuhong; Tvrdik, Petr; Makki, Nadja; Machold, Robert; Paxinos, George; Watson, Charles

    2013-02-15

    We have found a previously unreported precerebellar nucleus located among the emerging fibers of the motor root of the trigeminal nerve in the mouse, which we have called the interfascicular trigeminal nucleus (IF5). This nucleus had previously been named the tensor tympani part of the motor trigeminal nucleus (5TT) in rodent brain atlases, because it was thought to be a subset of small motor neurons of the motor trigeminal nucleus innervating the tensor tympani muscle. However, following injection of retrograde tracer in the cerebellum, the labeled neurons in IF5 were found to be choline acetyltransferase (ChAT) negative, indicating that they are not motor neurons. The cells of IF5 are strongly labeled in mice from Wnt1Cre and Atoh1 CreER lineage fate mapping, in common with the major precerebellar nuclei that arise from the rhombic lip and that issue mossy fibers. Analysis of sections from mouse Hoxa3, Hoxb1, and Egr2 Cre labeled lineages shows that the neurons of IF5 arise from rhombomeres caudal to rhombomere 4, most likely from rhombomeres 6-8. We conclude that IF5 is a significant precerebellar nucleus in the mouse that shares developmental gene expression characteristics with mossy fiber precerebellar nuclei that arise from the caudal rhombic lip.

  11. Fluctuations and correlations in nucleus-nucleus collisions within transport approaches

    Energy Technology Data Exchange (ETDEWEB)

    Konchakovski, Volodymyr P.

    2009-10-01

    The current thesis is devoted to a systematic study of fluctuations and correlations in heavy-ion collisions, which might be considered as probes for the phase transition and the critical point in the phase diagram, within the Hadron-String- Dynamics (HSD) microscopic transport approach. This is a powerful tool to study nucleus-nucleus collisions and allows to completely simulate experimental collisions on an event-by-event basis. Thus, the transport model has been used to study fluctuations and correlations including the influence of experimental acceptance as well as centrality, system size and collision energy. The comparison to experimental data can separate the effects induced by a phase transition since there is no phase transition in the HSD version used here. Firstly the centrality dependence of multiplicity fluctuations has been studied. Different centrality selections have been performed in the analysis in correspondence to the experimental situation. For the fixed target experiment NA49 events with fixed numbers of the projectile participants have been studied while in the collider experiment PHENIX centrality classes of events have been defined by the multiplicity in certain phase space region. A decrease of participant number fluctuations (and thus volume fluctuations) in more central collisions for both experiments has been obtained. Another area of this work addresses to transport model calculations of multiplicity fluctuations in nucleus-nucleus collisions as a function of colliding energy and system size. This study is in full correspondence to the experimental program of the NA61 Collaboration at the SPS. Central C+C, S+S, In+In, and Pb+Pb nuclear collisions at Elab = 10, 20, 30, 40, 80, 158 AGeV have been investigated. The expected enhanced fluctuations - attributed to the critical point and phase transition - can be observed experimentally on top of a monotonic and smooth 'hadronic background'. These findings should be helpful for the

  12. Questions and prospects in quarkonium polarization measurements from proton-proton to nucleus-nucleus collisions

    CERN Document Server

    Faccioli, Pietro

    2012-01-01

    Polarization measurements are the best instrument to understand how quark and antiquark combine into the different quarkonium states, but no model has so far succeeded in explaining the measured J/psi and Upsilon polarizations. On the other hand, the experimental data in proton-antiproton and proton-nucleus collisions are inconsistent, incomplete and ambiguous. New analyses will have to properly address often underestimated issues: the existence of azimuthal anisotropies, the dependence on the reference frame, the influence of the experimental acceptance on the comparison with other measurements and with theory. Additionally, a recently developed frame-invariant formalism will provide an alternative and often more immediate physical viewpoint and, at the same time, will help probing systematic effects due to experimental biases. The role of feed-down decays from heavier states, a crucial missing piece in the current experimental knowledge, will have to be investigated. Ultimately, quarkonium polarization meas...

  13. PREFACE: 11th International Conference on Nucleus-Nucleus Collisions (NN2012)

    Science.gov (United States)

    Li, Bao-An; Natowitz, Joseph B.

    2013-03-01

    The 11th International Conference on Nucleus-Nucleus Collisions (NN2012) was held from 27 May to 1 June 2012, in San Antonio, Texas, USA. It was jointly organized and hosted by The Cyclotron Institute at Texas A&M University, College Station and The Department of Physics and Astronomy at Texas A&M University-Commerce. Among the approximately 300 participants were a large number of graduate students and post-doctoral fellows. The Keynote Talk of the conference, 'The State of Affairs of Present and Future Nucleus-Nucleus Collision Science', was given by Dr Robert Tribble, University Distinguished Professor and Director of the TAMU Cyclotron Institute. During the conference a very well-received public lecture on neutrino astronomy, 'The ICEcube project', was given by Dr Francis Halzen, Hilldale and Gregory Breit Distinguished Professor at the University of Wisconsin, Madison. The Scientific program continued in the general spirit and intention of this conference series. As is typical of this conference a broad range of topics including fundamental areas of nuclear dynamics, structure, and applications were addressed in 42 plenary session talks, 150 parallel session talks, and 21 posters. The high quality of the work presented emphasized the vitality and relevance of the subject matter of this conference. Following the tradition, the NN2012 International Advisory Committee selected the host and site of the next conference in this series. The 12th International Conference on Nucleus-Nucleus Collisions (NN2015) will be held 21-26 June 2015 in Catania, Italy. It will be hosted by The INFN, Laboratori Nazionali del Sud, INFN, Catania and the Dipartimento di Fisica e Astronomia of the University of Catania. The NN2012 Proceedings contains the conference program and 165 articles organized into the following 10 sections 1. Heavy and Superheavy Elements 2. QCD and Hadron Physics 3. Relativistic Heavy-Ion Collisions 4. Nuclear Structure 5. Nuclear Energy and Applications of

  14. Morphology of Human Nucleus Accumbens Neurons Based on the Immunohistochemical Expression of Gad67

    Directory of Open Access Journals (Sweden)

    Sazdanovic Maja

    2016-12-01

    Full Text Available The nucleus accumbens is a part of the ventral striatum along with the caudate nucleus and putamen. The role of the human nucleus accumbens in drug addiction and other psychiatric disorders is of great importance. The aim of this study was to characterize medium spiny neurons in the nucleus accumbens according to the immunohistochemical expression of GAD67.

  15. The red nucleus and the rubrospinal projection in the mouse.

    Science.gov (United States)

    Liang, Huazheng; Paxinos, George; Watson, Charles

    2012-04-01

    We studied the organization and spinal projection of the mouse red nucleus with a range of techniques (Nissl stain, immunofluorescence, retrograde tracer injections into the spinal cord, anterograde tracer injections into the red nucleus, and in situ hybridization) and counted the number of neurons in the red nucleus (3,200.9 ± 230.8). We found that the rubrospinal neurons were mainly located in the parvicellular region of the red nucleus, more lateral in the rostral part and more medial in the caudal part. Labeled neurons were least common in the rostral and caudal most parts of the red nucleus. Neurons projecting to the cervical cord were predominantly dorsomedially placed and neurons projecting to the lumbar cord were predominantly ventrolaterally placed. Immunofluorescence staining with SMI-32 antibody showed that ~60% of SMI-32-positive neurons were cervical cord-projecting neurons and 24% were lumbar cord-projecting neurons. SMI-32-positive neurons were mainly located in the caudomedial part of the red nucleus. A study of vGluT2 expression showed that the number and location of glutamatergic neurons matched with those of the rubrospinal neurons. In the anterograde tracing experiments, rubrospinal fibers travelled in the dorsal portion of the lateral funiculus, between the lateral spinal nucleus and the calretinin-positive fibers of the lateral funiculus. Rubrospinal fibers terminated in contralateral laminae 5, 6, and the dorsal part of lamina 7 at all spinal cord levels. A few fibers could be seen next to the neurons in the dorsolateral part of lamina 9 at levels of C8-T1 (hand motor neurons) and L5-L6 (foot motor neurons), which is consistent with a view that rubrospinal fibers may play a role in distal limb movement in rodents.

  16. Nucleus Pearl Coating Process of Freshwater Mussel Anodonta woodiana (Unionidae

    Directory of Open Access Journals (Sweden)

    WASMEN MANALU

    2013-03-01

    Full Text Available The limiting factor which is a weakness of sea water pearl production are high costs, the risk of major business failures and a long coating time. From the issue of freshwater pearls appear to have prospects of alternative substitution for sea water pearl. This present study aimed to evaluate effect of loads (the number and diameter nucleus on freshwater pearl coating process and the number and size of the appropriate nucleus diameter, to produce the optimum coating thickness of half-round pearls. The research consists of experimental implantation of 2, 4, and 6 nucleus number per individual mussel was maintained by the method stocked in hapa in bottom waters. Observation method and factorial randomized block design used in the study of the influence of the load to the successfulness of pearl coating and the pearl layer thickness. The results showed that A. woodiana can be utilized as a producer of freshwater pearls. In addition, the number of optimum nucleus that can be attached to the mussel A. woodiana was 2 grains/individuals with a diameter of 10 mm. Shells implanted with the optimum nucleus diameter and number of pearls produced the highest layer thickness of 17 m after 9 months cultivation. This result was good enough compared with the layer thickness of sea water pearl production after the same cultivation time.

  17. Alteration of Paramecium candatum germinal nucleus morphology after UV irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Fokin, S.I. (Leningradskij Gosudarstvennyj Univ. (USSR). Biologicheskij Nauchno-Issledovatel' skij Inst.)

    1982-09-01

    A study was made on morphologic changes of micronucleus (Mi) after whole-body ultraviolet (UV) irradiation of paramecia as well as after local irradiation of this nucleus or the area of macronucleus (Ma). The whole-body irradiation of its Ma part leads to generative nucleus growth in sizes and chromatin structure change, which is expressed in occurence of large chromatin bodies. Aftereffects of local action on Mi for viable descendants are expressed in nucleus size transformation (usually in reduction), gaining ''comet-shaped'' form and probably in reduction of dna amount. Irradiation of Ma and total effect on cell cause Mi changes of reversible character. All morphologic changes of Mi after local ultraviolet irradiation are conserved in descendants and are not photoreactivated. Possible reasons for this phenomenon are discussed. The results obtained make it possible to speak about different mechanisms of action on Mi in the case of local and whole-body UV irradiation of cell. The effect of irradiated Ma on generative nucleus, but not direct damage of this nucleus is the reason for Mi morphologic reconstruction after whole-body action on paramecium.

  18. The stellar population of the decoupled nucleus in M 31

    CERN Document Server

    Silchenko, O K; Vlasyuk, V V

    1998-01-01

    The results of a spectroscopic and photometric investigation of the central region of M 31 are presented. An analysis of absorption-index radial profiles involving magnesium, calcium, and iron lines has shown that the unresolved nucleus of M 31 is distinct by its increased metallicity; unexpectedly, among two nuclei of M 31, it is the faintest one located exactly in the dynamical center of the galaxy (and dynamically decoupled) which is chemically distinct. The Balmer absorption line H-beta has been included into the analysis to disentangle metallicity and age effects; an age difference by a factor 3 is detected between stellar populations of the nucleus and of the bulge, the nucleus being younger. The morphological analysis of CCD images has revealed the presence of a nuclear stellar-gaseous disk with a radius of some 100 pc, the gas component of which looks non-stationary, well inside the bulge of M 31.

  19. Low energy neutron inelastic scattering on /sup 152/Sm nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, D.J.R.; Cabezas, S.R.; Lopez, M.R.

    1984-01-01

    A study of inelastic neutron scattering by the nucleus /sup 152/Sm at incident energies of 2.47 and 2.75 MeV using the coupled-channel method has been made. Consideration is made of the 2/sup +//0.122 MeV/, 4/sup +//0.366 MeV/ and 2/sup +//1.086 MeV/excited states. It is shown that in this energy range the process may be described satisfactorily considering /sup 152/Sm as a deformed nucleus with non-axial symmetry, given the quadrupole and hexadecapole deformations. The scattering process through the compound nucleus is calculated according to the Hauser-Feshbach formula with width fluctuation correction. It is shown that the presence of direct excitation process is partly due to the non-axiality of /sup 152/Sm.

  20. Separable Representation of Multichannel Nucleon-Nucleus Optical Potentials

    CERN Document Server

    Hlophe, Linda

    2016-01-01

    One important ingredient for many applications of nuclear physics to astrophysics, nuclear energy, and stockpile stewardship are cross sections for reactions of neutrons with rare isotopes. Since direct measurements are often not feasible, indirect methods, e.g. (d,p) reactions, should be used. Those (d,p) reactions may be viewed as three-body reactions and described with Faddeev techniques. Faddeev equations in momentum space have a long tradition of utilizing separable interactions in order to arrive at sets of coupled integral equations in one variable. Optical potentials representing the effective interactions in the neutron (proton) nucleus subsystem are usually non-Hermitian as well as energy-dependent. Including excitations of the nucleus in the calculation requires a multichannel optical potential. The purpose of this paper is to introduce a separable, energy-dependent multichannel representation of complex, energy-dependent optical potentials that contain excitations of the nucleus and that fulfill r...

  1. Reaction cross sections of the deformed halo nucleus 31Ne

    CERN Document Server

    Urata, Y; Sagawa, H

    2012-01-01

    Using the Glauber theory, we calculate reaction cross sections for the deformed halo nucleus $^{31}$Ne. To this end, we assume that the $^{31}$Ne nucleus takes the $^{30}$Ne + $n$ structure. In order to take into account the rotational excitation of the core nucleus $^{30}$Ne, we employ the particle-rotor model (PRM). We compare the results to those in the adiabatic limit of PRM, that is, the Nilsson model, and show that the Nilsson model works reasonably well for the reaction cross sections of $^{31}$Ne. We also investigate the dependence of the reaction cross sections on the ground state properties of $^{31}$Ne, such as the deformation parameter and the p-wave component in the ground state wave function.

  2. Microinjection of limonene into caudate nucleus inhibits IMC of rats

    Institute of Scientific and Technical Information of China (English)

    Hong Guo; Xin Yi Zhu; Yi Quan Wei; De Zhi Yang

    2000-01-01

    AIM We have discovered that Limonene modulates interdigestive myoelectrical complexes (IMCs) ofgastrointestinal tract in rats. In this research we will elucidate weather limonene affects acetylcholine M-receptor in caudate nucleus.METHODS Changes of IMCs were studied after limonene and/or atropine were microinjected into caudatenucleus. IMCs were recorded by a RM-6200 four-channel recorder and then delivered to Maclab and PowerMacintosh.RESULTS The active phases of IMCs occupied about 40% of total cycle in average. After microinjection oflimonene into caudate nucleus, the active phases were significantly shortened, while the cycle time of IMCswere not changed significantly. The inhibitory effects of limonene were abolished by pretreatment withatropine, whilst the atropine has no effect on IMCs.CONCLUSION It is suggested that limonene inhabits the gastrointestinal IMCs by affecting M-receptor incaudate nucleus.

  3. Extreme alpha-clustering in the 18O nucleus

    CERN Document Server

    Johnson, E D; Goldberg, V Z; Brown, S; Robson, D; Crisp, A M; Cottle, P D; Fu, C; Giles, J; Green, B W; Kemper, K W; Lee, K; Roeder, B T; Tribble, R E

    2009-01-01

    The structure of the 18O nucleus at excitation energies above the alpha decay threshold was studied using 14C+alpha resonance elastic scattering. A number of states with large alpha reduced widths have been observed, indicating that the alpha-cluster degree of freedom plays an important role in this N not equal Z nucleus. However, the alpha-cluster structure of this nucleus is very different from the relatively simple pattern of strong alpha-cluster quasi-rotational bands in the neighboring 16O and 20Ne nuclei. A 0+ state with an alpha reduced width exceeding the single particle limit was identified at an excitation energy of 9.9+/-0.3 MeV. We discuss evidence that states of this kind are common in light nuclei and give possible explanations of this feature.

  4. New integral formula and its applications to light nucleus reactions

    CERN Document Server

    Sun, Xiaojun

    2015-01-01

    A new integral formula, which has not been compiled in any integral tables or mathematical softwares, is proposed to obtain the analytical energy-angular spectra of the particles that are sequentially emitted from the discrete energy levels of the residual nuclei in the statistical theory of light nucleus reaction (STLN). In the cases of the neutron induced light nucleus reactions, the demonstration of the kinetic energy conservation in the sequential emission processes becomes straightforward thanks to this new integral formula and it is also helpful to largely reduce the volume of file-6 in nuclear reaction databases. Furthermore, taking p+$^9$Be reaction at 18 MeV as an example, this integral formula is extended to calculate the energy-angular spectra of the sequentially emitted neutrons for proton induced light nucleus reactions in the frame of STLN.

  5. Comparison of neuronal activities of external cuneate nucleus, spinocerebellar cortex and interpositus nucleus during passive movements of the rat's forelimb.

    Science.gov (United States)

    Casabona, A; Valle, M S; Bosco, G; Perciavalle, V

    2008-11-11

    In this paper we examined the neuronal activities of external cuneate nucleus, spinocerebellar Purkinje cells and interpositus nucleus during passive forelimb movements in anesthetized rats with the aim of identifying common or different patterns of activation across structures. By means of principal components analysis, we identified two main patterns of discharge which explained most of the dataset variance. One component characterized the movement-related activity of external cuneate and spinocerebellar cortical neurons, while the other reflected neuronal activity of the interpositus nucleus. We also found that both principal components were related to global forelimb kinematics but, while most of the variance of the activity of external cuneate cells and spinocerebellar Purkinje cells was explained by the limb axis orientation and orientation velocity, interpositus neurons' firing was best related to length and length velocity. This difference in the forelimb kinematics representation observed in external cuneate nucleus and spinocerebellar cortex compared with the interpositus nucleus is discussed with respect to the specific role that these structures may play also during active control of limb movements.

  6. Immobility, inheritance and plasticity of shape of the yeast nucleus

    Directory of Open Access Journals (Sweden)

    Andrulis Erik D

    2007-11-01

    Full Text Available Abstract Background Since S. cerevisiae undergoes closed mitosis, the nuclear envelope of the daughter nucleus is continuous with that of the maternal nucleus at anaphase. Nevertheless, several constitutents of the maternal nucleus are not present in the daughter nucleus. The present study aims to identify proteins which impact the shape of the yeast nucleus and to learn whether modifications of shape are passed on to the next mitotic generation. The Esc1p protein of S. cerevisiae localizes to the periphery of the nucleoplasm, can anchor chromatin, and has been implicated in targeted silencing both at telomeres and at HMR. Results Upon increased Esc1p expression, cell division continues and dramatic elaborations of the nuclear envelope extend into the cytoplasm. These "escapades" include nuclear pores and associate with the nucleolus, but exclude chromatin. Escapades are not inherited by daughter nuclei. This exclusion reflects their relative immobility, which we document in studies of prezygotes. Moreover, excess Esc1p affects the levels of multiple transcripts, not all of which originate at telomere-proximal loci. Unlike Esc1p and the colocalizing protein, Mlp1p, overexpression of selected proteins of the inner nuclear membrane is toxic. Conclusion Esc1p is the first non-membrane protein of the nuclear periphery which – like proteins of the nuclear lamina of higher eukaryotes – can modify the shape of the yeast nucleus. The elaborations of the nuclear envelope ("escapades" which appear upon induction of excess Esc1p are not inherited during mitotic growth. The lack of inheritance of such components could help sustain cell growth when parental nuclei have acquired potentially deleterious characteristics.

  7. Morphometric study of dentate nucleus of cerebellum in Bangladeshi cadaver.

    Science.gov (United States)

    Haque, M A; Khalil, M; Sultana, S Z; Mannan, S; Uddin, M M; Hossain, M; Ara, A; Choudhury, S; Shammi, N J

    2015-01-01

    This cross sectional descriptive study was done by using nonprobability sampling technique and performed by examining 63 (sixty three) cerebellum. Out of them 40 postmortem human cerebellum collected from Bangladeshi cadavers of both sexes (male 25 and female 15) age ranging from 5 to 60 years and 23 cerebellums from caesarian section of intrauterine death cases of both sexes (male 14 and female 9) age ranging from 34 to 41 weeks of gestation. Specimens were collected from dead bodies autopsied on different dates from April' 2009 to September' 2009 at the autopsy laboratory of department of Forensic Medicine and prenatal cases from Gynaecology and Obstetrics Department of Mymensingh Medical College, Mymensingh. The collected specimens were grouped into three age groups like Group A (28 to 42 weeks of gestation), Group B (5 to 30 years) and Group C (31 to 60 years) and, two sex groups (male and female) and two sides (right and left). A transverse section was made at the level of horizontal fissure, and length and breadth of dentate nucleus were measured by divider and scale. The mean (±SD) length and breadth of dentate nucleus was 8.619±2.995mm and 14.770±3.604mm respectively and it was observed that length and breadth of dentate nucleus increased with age upto certain level then slightly decreased in the late age Group C. In this study, differences of the mean length of dentate nucleus on both right and left sides were statistically moderately significant between age Groups A&B. The differences of mean breadth of dentate nucleus on both right and left side were statistically highly significant between age Groups A&B and moderately significant between age Groups A&C on right side and only significant on left side. The differences between male & female were statistically insignificant in length and breadth of dentate nucleus.

  8. Silk fibroin porous scaffolds for nucleus pulposus tissue engineering

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Chao; Yang, Qiang [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Tianjin Medical University, Tianjin 300070 (China); Zhu, Meifeng [The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071 (China); Du, Lilong [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Tianjin Medical University, Tianjin 300070 (China); Zhang, Jiamin [The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071 (China); Ma, Xinlong [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Xu, Baoshan, E-mail: xubaoshan99@126.com [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Wang, Lianyong, E-mail: wly@nankai.edu.cn [The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071 (China)

    2014-04-01

    Intervertebral discs (IVDs) are structurally complex tissue that hold the vertebrae together and provide mobility to spine. The nucleus pulposus (NP) degeneration often results in degenerative IVD disease that is one of the most common causes of back and neck pain. Tissue engineered nucleus pulposus offers an alternative approach to regain the function of the degenerative IVD. The aim of this study is to determine the feasibility of porous silk fibroin (SF) scaffolds fabricated by paraffin-sphere-leaching methods with freeze-drying in the application of nucleus pulposus regeneration. The prepared scaffold possessed high porosity of 92.38 ± 5.12% and pore size of 165.00 ± 8.25 μm as well as high pore interconnectivity and appropriate mechanical properties. Rabbit NP cells were seeded and cultured on the SF scaffolds. Scanning electron microscopy, histology, biochemical assays and mechanical tests revealed that the porous scaffolds could provide an appropriate microstructure and environment to support adhesion, proliferation and infiltration of NP cells in vitro as well as the generation of extracellular matrix. The NP cell–scaffold construction could be preliminarily formed after subcutaneously implanted in a nude mice model. In conclusion, The SF porous scaffold offers a potential candidate for tissue engineered NP tissue. - Highlights: • Paraffin microsphere-leaching method is used to fabricate silk fibroin scaffold. • The scaffold has appropriate mechanical property, porosity and pore size • The scaffold supports growth and infiltration of nucleus pulposus cells. • Nucleus pulposus cells can secrete extracellular matrix in the scaffolds. • The scaffold is a potential candidate for tissue engineered nucleus pulposus.

  9. Slow flow of passive neutrophils and sequestered nucleus into micropipette.

    Science.gov (United States)

    Kaleridis, V; Athanassiou, G; Deligianni, D; Missirlis, Y

    2010-01-01

    In the present study, the role of the nucleus and its contribution to the deformability of the passive neutrophils was investigated. To determine the rheological properties of the nucleus and of the neutrophil itself, deformation tests on single neutrophil and sequestered nucleus have been performed by micropipette under low aspiration pressure (80 Pa = 2-3 Pcr). The stiffness of the nucleus was found to be larger than that of the neutrophil, and its viscosity was found almost ten-fold higher. A subpopulation of neutrophils (Sub-A) showed two phases of deformation, a first rapid phase and a second phase with a constant deformation rate up to their full entrance, with an apparent viscosity mu app-second-Phase(N Sub-A) = 286 +/- 123 Pa x s, calculated by the liquid drop model. Another subpopulation (Sub-B) of the tested neutrophils displayed three deformation phases: a first one reflecting the rapid entry of cell into the micropipette, a second with constant deformation rate, and a third phase, with a slower, also constant, deformation rate were recorded. The corresponding apparent viscosities were found as mu app-second-Phase(N Sub-B) = 341 +/- 94 Pa x s and mu app-third-Phase(N Sub-B) = 1651 +/- 734 Pa x s. The apparent viscosity values of the neutrophilic nucleus, mu app (N nucl) = 2468 +/- 1345 Pa x s and of the whole neutrophil calculated in the third phase of deformation, mu app-third-Phase(N Sub-B) = 1651 +/- 734 Pa.s were comparable. These results support our hypothesis that the nucleus plays a significant role in the mechanical and rheological behavior of the neutrophil, especially when it has to pass through openings much smaller than its size.

  10. Brain networks modulated by subthalamic nucleus deep brain stimulation.

    Science.gov (United States)

    Accolla, Ettore A; Herrojo Ruiz, Maria; Horn, Andreas; Schneider, Gerd-Helge; Schmitz-Hübsch, Tanja; Draganski, Bogdan; Kühn, Andrea A

    2016-09-01

    Deep brain stimulation of the subthalamic nucleus is an established treatment for the motor symptoms of Parkinson's disease. Given the frequent occurrence of stimulation-induced affective and cognitive adverse effects, a better understanding about the role of the subthalamic nucleus in non-motor functions is needed. The main goal of this study is to characterize anatomical circuits modulated by subthalamic deep brain stimulation, and infer about the inner organization of the nucleus in terms of motor and non-motor areas. Given its small size and anatomical intersubject variability, functional organization of the subthalamic nucleus is difficult to investigate in vivo with current methods. Here, we used local field potential recordings obtained from 10 patients with Parkinson's disease to identify a subthalamic area with an analogous electrophysiological signature, namely a predominant beta oscillatory activity. The spatial accuracy was improved by identifying a single contact per macroelectrode for its vicinity to the electrophysiological source of the beta oscillation. We then conducted whole brain probabilistic tractography seeding from the previously identified contacts, and further described connectivity modifications along the macroelectrode's main axis. The designated subthalamic 'beta' area projected predominantly to motor and premotor cortical regions additional to connections to limbic and associative areas. More ventral subthalamic areas showed predominant connectivity to medial temporal regions including amygdala and hippocampus. We interpret our findings as evidence for the convergence of different functional circuits within subthalamic nucleus' portions deemed to be appropriate as deep brain stimulation target to treat motor symptoms in Parkinson's disease. Potential clinical implications of our study are illustrated by an index case where deep brain stimulation of estimated predominant non-motor subthalamic nucleus induced hypomanic behaviour.

  11. Recent Developments in Neutrino/Antineutrino-Nucleus Interactions

    Directory of Open Access Journals (Sweden)

    Jorge G. Morfín

    2012-01-01

    Full Text Available Recent experimental results and developments in the theoretical treatment of neutrino-nucleus interactions in the energy range of 1–10 GeV are discussed. Difficulties in extracting neutrino-nucleon cross sections from neutrino-nucleus scattering data are explained and significance of understanding nuclear effects for neutrino oscillation experiments is stressed. Detailed discussions of the status of two-body current contribution in the kinematic region dominated by quasielastic scattering and specific features of partonic nuclear effects in weak DIS scattering are presented.

  12. Spectra Statistics for the Odd-Odd Nucleus 86Nb

    Institute of Scientific and Technical Information of China (English)

    ZHENG Ren-Rong; ZHU Shun-Quan; CHENG Nan-Pu

    2001-01-01

    The energy levels of the odd-odd nucleus 86 Nb at low spins are calculated by using quasi-particles plus a rotor model. The distribution of the nearest-neighbour spacing and the spectral rigidity are studied. We find that the chaotic degree of the energy spectra increases with the increasing spin and reaches a maximum at I = 10; then it decreases gradually for spins above I = 10. The recoil term in the model Haniltonian makes the energy spectra slightly regular. The Coriolis force, however, makes the spectra chaotic and plays a major role in the spectral statistics of the odd-odd nucleus 86Nb.

  13. Recent Developments in Neutrino/Antineutrino-Nucleus Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Morfín, Jorge G.; Nieves, Juan; Sobczyk, Jan T.

    2012-01-01

    Recent experimental results and developments in the theoretical treatment of neutrino-nucleus interactions in the energy range of 1–10 GeV are discussed. Difficulties in extracting neutrino-nucleon cross sections from neutrino-nucleus scattering data are explained and significance of understanding nuclear effects for neutrino oscillation experiments is stressed. Detailed discussions of the status of two-body current contribution in the kinematic region dominated by quasielastic scattering and specific features of partonic nuclear effects in weak DIS scattering are presented.

  14. Formation and decay of a hot compound nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, B.V.; Dalmolin, F.T.; Dutra, M.; Santos, T.J., E-mail: brett@ita.br [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos SP (Brazil); Souza, S.R. [Universidade Federal de Rio Grande do Sul (UFRS), Porto Alegre RS, (Brazil); Universidade Federal de Rio de Janeiro (UFRJ), RJ (Brazil). Instituto de Fisica; Donangelo, R. [Instituto de Fisica, Universidad de la Republica de Uruguay, Montevideo (Uruguay); Universidade Federal de Rio Grande do Sul (UFRS), Porto Alegre RS, (Brazil)

    2014-07-01

    The compound nucleus plays an important role in nuclear reactions over a wide range of projectile-target combinations and energies. The limits that angular momentum places on its formation and existence are, for the most part, well understood. The limits on its excitation energy are not as clear. Here we first analyze general geometrical and thermodynamical features of a hot compound nucleus. We then discuss the manners by which it can decay and close by speculating on the high energy limit to its formation and existence. (author)

  15. Separable Representation of Proton-Nucleus Optical Potentials

    CERN Document Server

    Hlophe, L; Elster, Ch; Nunes, F M; Arbanas, G; Escher, J E; Thompson, I J

    2014-01-01

    Recently, a new approach for solving the three-body problem for (d,p) reactions in the Coulomb-distorted basis in momentum space was proposed. Important input quantities for such calculations are the scattering matrix elements for proton- and neutron-nucleus scattering. We present a generalization of the Ernst-Shakin-Thaler scheme in which a momentum space separable representation of proton-nucleus scattering matrix elements can be calculated in the Coulomb basis. The viability of this method is demonstrated by comparing S-matrix elements obtained for p$+^{48}$Ca and p$+^{208}$Pb for a phenomenological optical potential with corresponding coordinate space calculations.

  16. Final State Interactions Effects in Neutrino-Nucleus Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Golan, Tomasz [Univ. of Wroctaw (Poland); Juszczak, Cezary [Univ. of Wroctaw (Poland); Sobczyk, Jan T. [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States)

    2012-07-01

    Final State Interactions effects are discussed in the context of Monte Carlo simulations of neutrino-nucleus interactions. A role of Formation Time is explained and several models describing this effect are compared. Various observables which are sensitive to FSI effects are reviewed including pion-nucleus interaction and hadron yields in backward hemisphere. NuWro Monte Carlo neutrino event generator is described and its ability to understand neutral current $\\pi^0$ production data in $\\sim 1$ GeV neutrino flux experiments is demonstrated.

  17. Neurophysiological evaluation of the pedunculopontine nucleus in humans.

    Science.gov (United States)

    Profice, P; Mazzone, P; Pilato, F; Dileone, M; Insola, A; Ranieri, F; Di Lazzaro, V

    2011-10-01

    The pedunculopontine nucleus (PPTg) is constituted by a heterogeneous cluster of neurons located in caudal mesencephalic tegmentum which projects to the thalamus to trigger thalamocortical rhythms and the brainstem to modulate muscle tone and locomotion. It has been investigated as potential deep brain stimulation (DBS) target for treating Parkinson's disease (PD) symptoms. Neurophysiological studies conducted in humans using DBS electrodes for exploring functional properties of PPTg in vivo, reviewed in this paper, demonstrated that the functional connections between PPTg and cortex, basal ganglia, brainstem network involved in sleep/wake control, and spinal cord can be explored in vivo and provided useful insights about the physiology of this nucleus and pathophysiology of PD.

  18. Odd-Even Nucleus Calculation Using exp(S) Method.

    Science.gov (United States)

    Mihaila, Bogdan; Heisenberg, Jochen

    1997-04-01

    We apply the equation of motion technique to calculate the ground state and excited states of the nucleus ^15N. First, we define a complete basis for ^15N relative to the reference ^16O ground state, | A >. Then, the eigenstate | (A-1)j > with energy Ej are given as a linear superposition of these basis configurations. Assuming that this state is an eigenstate of the many-body Hamiltonian, we solve an eigenvalue problem for the energies and wave functions describing the excited states of the ^15N nucleus.

  19. CASTOR The ALICE forward detector for identification of Centauros and Strangelets in Nucleus-Nucleus Collisions at the LHC

    CERN Document Server

    Angelis, Aris L S; Bogolyubsky, M Yu; Filippov, S N; Gladysz-Dziadus, E; Kharlov, Yu V; Kurepin, A B; Maevskaya, A I; Mavromanolakis, G; Panagiotou, A D; Sadovsky, S A; Stefanski, P; Wlodarczyk, Z; Kharlov, Yu. V.

    1999-01-01

    The physics motivation for a very forward detector for the ALICE heavy ion experiment at the CERN LHC is discussed. A phenomenological model describing the formation and decay of a Centauro fireball in nucleus-nucleus collisions is presented. The CASTOR detector which is aimed to measure the hadronic and photonic content of an interaction and to identify deeply penetrating objects in the very forward, baryon-rich phase space 5.6 < eta < 7.2 in an event-by-event mode is described. Results of simulations of the expected response of the calorimeter, and in particular to the passage of strangelets, are presented.

  20. Altered morphology of the nucleus accumbens in persistent developmental stuttering.

    Science.gov (United States)

    Neef, Nicole E; Bütfering, Christoph; Auer, Tibor; Metzger, F Luise; Euler, Harald A; Frahm, Jens; Paulus, Walter; Sommer, Martin

    2017-05-24

    Neuroimaging studies in persistent developmental stuttering repeatedly report altered basal ganglia functions. Together with thalamus and cerebellum, these structures mediate sensorimotor functions and thus represent a plausible link between stuttering and neuroanatomy. However, stuttering is a complex, multifactorial disorder. Besides sensorimotor functions, emotional and social-motivational factors constitute major aspects of the disorder. Here, we investigated cortical and subcortical gray matter regions to study whether persistent developmental stuttering is also linked to alterations of limbic structures. The study included 33 right-handed participants who stutter and 34 right-handed control participants matched for sex, age, and education. Structural images were acquired using magnetic resonance imaging to estimate volumetric characteristics of the nucleus accumbens, hippocampus, amygdala, pallidum, putamen, caudate nucleus, and thalamus. Volumetric comparisons and vertex-based shape comparisons revealed structural differences. The right nucleus accumbens was larger in participants who stutter compared to controls. Recent theories of basal ganglia functions suggest that the nucleus accumbens is a motivation-to-movement interface. A speaker intends to reach communicative goals, but stuttering can derail these efforts. It is therefore highly plausible to find alterations in the motivation-to-movement interface in stuttering. While behavioral studies of stuttering sought to find links between the limbic and sensorimotor system, we provide the first neuroimaging evidence of alterations in the limbic system. Thus, our findings might initialize a unified neurobiological framework of persistent developmental stuttering that integrates sensorimotor and social-motivational neuroanatomical circuitries. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Inclusive jet production in ultrarelativistic proton-nucleus collisions

    CERN Document Server

    Perepelitsa, Dennis

    High-$p_\\mathrm{T}$ processes in proton- and deuteron-nucleus collisions at TeV energies are the best presently available way to study the partonic structure of the nucleus in a high-density regime. Jet production over a wide range of phase space can significantly constrain the current knowledge of nuclear parton distribution functions (nPDFs), which are substantially less well understood than the corresponding PDFs in protons and which have only recently begun to be treated in a spatially-dependent way. An accurate knowledge of nPDFs is crucial for a definitive control of perturbative processes in a cold nuclear environment, since high-$p_\\mathrm{T}$ probes are used to quantitatively investigate the hot QCD matter created in ultrarelativistic nucleus-nucleus collisions. Furthermore, jets from low Bjorken-$x$ partons can probe the transition from the dilute to saturated nuclear regimes. Jet production is investigated in $d$+Au collisions at $\\sqrt{s} = 200$ GeV with the PHENIX detector at the Relativistic Hea...

  2. RELATIVISTIC CALCULATIONS OF THE SUPERHEAVY NUCLEUS 114-298

    NARCIS (Netherlands)

    BOERSMA, HF

    1993-01-01

    We investigate ground-state properties of the superheavy nucleus with N = 184 and Z = 114, (298)114, using conventional relativistic mean-field theory and density-dependent mean-field theory, which reproduces Dirac-Brueckner calculations in nuclear matter. Our calculations provide support for N = 18

  3. Empirical Example of Nucleus with Transitional Dynamical Symmetry X(5)

    Institute of Scientific and Technical Information of China (English)

    张大立; 赵惠英

    2002-01-01

    By analysing the energy spectrum, E2 transition rates and branching ratios, it is shown explicitly that the nucleus 150Nd provides an empirical example with X(5) symmetry at the critical point of the transition from U(5) to SU(3) symmetry.

  4. Rapid feedback processing in human nucleus accumbens and motor thalamus

    NARCIS (Netherlands)

    Schüller, T.; Gründler, T.O.J.; Jocham, G.; Klein, T.A.; Timmermann, L.; Visser-Vandewalle, V.E.R.M.; Kuhn, J.

    2015-01-01

    The nucleus accumbens (NAcc) and thalamus are integral parts in models of feedback processing. Deep brain stimulation (DBS) has been successfully employed to alleviate symptoms of psychiatric conditions including obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS). Common target structu

  5. Calcium-regulated import of myosin IC into the nucleus.

    Science.gov (United States)

    Maly, Ivan V; Hofmann, Wilma A

    2016-06-01

    Myosin IC is a molecular motor involved in intracellular transport, cell motility, and transcription. Its mechanical properties are regulated by calcium via calmodulin binding, and its functions in the nucleus depend on import from the cytoplasm. The import has recently been shown to be mediated by the nuclear localization signal located within the calmodulin-binding domain. In the present paper, it is demonstrated that mutations in the calmodulin-binding sequence shift the intracellular distribution of myosin IC to the nucleus. The redistribution is displayed by isoform B, described originally as the "nuclear myosin," but is particularly pronounced with isoform C, the normally cytoplasmic isoform. Furthermore, experimental elevation of the intracellular calcium concentration induces a rapid import of myosin into the nucleus. The import is blocked by the importin β inhibitor importazole. These findings are consistent with a mechanism whereby calmodulin binding prevents recognition of the nuclear localization sequence by importin β, and the steric inhibition of import is released by cell signaling leading to the intracellular calcium elevation. The results establish a mechanistic connection between the calcium regulation of the motor function of myosin IC in the cytoplasm and the induction of its import into the nucleus. © 2016 Wiley Periodicals, Inc.

  6. Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms.

    Science.gov (United States)

    Good, Matthew C

    2015-06-08

    Reporting in Developmental Cell, Hara and Merten (2015) apply the use of microfabrication and in vitro analysis in cell-free extracts to the old problem of nuclear size control. The authors make insights into the regulation of nuclear growth that potentially explain the widely reported correlation between nucleus size and cell size. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Saturating Cronin effect in ultrarelativistic proton-nucleus collisions

    CERN Document Server

    Papp, G; Fái, G; Papp, Gabor; Levai, Peter; Fai, George

    2000-01-01

    Pion and photon production cross sections are analyzed in proton-proton and proton-nucleus collisions at energies 20 GeV < s^1/2 < 60 GeV. We separate the proton-proton and nuclear contributions to transverse-momentum broadening and suggest a new mechanism for the nuclear enhancement in the high transverse-momentum region.

  8. Nucleus accumbens dopamine receptors in the consolidation of spatial memory.

    NARCIS (Netherlands)

    Mele, A.; Avena, M.; Roullet, P.; Leonibus, E. de; Mandillo, S.; Sargolini, F.; Coccurello, R.; Oliverio, A.

    2004-01-01

    Nucleus accumbens dopamine is known to play an important role in motor activity and in behaviours governed by drugs and natural reinforcers, as well as in non-associative forms of learning. At the same time, activation of D1 and D2 dopamine receptors has been suggested to promote intracellular event

  9. The nucleus of Darkschwitsch in Pantodactylus schreiberii Wiegmann (Lacertilia, Reptilia).

    Science.gov (United States)

    Quiroga, J C

    1977-01-01

    The nuclear mass considered the representative of the nucleus of Darkschwitsch in reptiles in studied. It is composed of small, stellate, pyriform or rounded cells, with two or three dendritic trunks resolved in a plexus near the cellular body. Its axons take an ascending direction to the posterior commissure, and not to be medial longitudinal fasciculus as has been conventionally described.

  10. CTP synthase forms cytoophidia in the cytoplasm and nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Gou, Ke-Mian [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193 (China); Chang, Chia-Chun [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Shen, Qing-Ji [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); Sung, Li-Ying, E-mail: liyingsung@ntu.edu.tw [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan, ROC (China); Liu, Ji-Long, E-mail: jilong.liu@dpag.ox.ac.uk [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom)

    2014-04-15

    CTP synthase is an essential metabolic enzyme responsible for the de novo synthesis of CTP. Multiple studies have recently showed that CTP synthase protein molecules form filamentous structures termed cytoophidia or CTP synthase filaments in the cytoplasm of eukaryotic cells, as well as in bacteria. Here we report that CTP synthase can form cytoophidia not only in the cytoplasm, but also in the nucleus of eukaryotic cells. Both glutamine deprivation and glutamine analog treatment promote formation of cytoplasmic cytoophidia (C-cytoophidia) and nuclear cytoophidia (N-cytoophidia). N-cytoophidia are generally shorter and thinner than their cytoplasmic counterparts. In mammalian cells, both CTP synthase 1 and CTP synthase 2 can form cytoophidia. Using live imaging, we have observed that both C-cytoophidia and N-cytoophidia undergo multiple rounds of fusion upon glutamine analog treatment. Our study reveals the coexistence of cytoophidia in the cytoplasm and nucleus, therefore providing a good opportunity to investigate the intracellular compartmentation of CTP synthase. - Highlights: • CTP synthase forms cytoophidia not only in the cytoplasm but also in the nucleus. • Glutamine deprivation and Glutamine analogs promotes cytoophidium formation. • N-cytoophidia exhibit distinct morphology when compared to C-cytoophidia. • Both CTP synthase 1 and CTP synthase 2 form cytoophidia in mammalian cells. • Fusions of cytoophidia occur in the cytoplasm and nucleus.

  11. Physical interrelation of volatile and refractories in a cometary nucleus

    Science.gov (United States)

    Fulle, Marco; Alice Team; Stern, Alan; CONSTERT Team; Kofman, Wlodek; COSIMA Team; Hilchenbach, Martin; GIADA Team; Rotundi, Alessandra; MIDAS Team; Bentley, Mark; MIRO Team; Hofstadter, Mark; OSIRIS Team; Sierks, Holger; ROSINA Team; Altwegg, Kathrin; RPC Team; Nilsson, Hans; Burch, James; Eriksson, Anders; Heinz-Glassmeier, Karl; Henri, Pierre; Carr, Christopher; RSI Team; Paetzold, Martin; , VIRTIS Team; Capaccioni, Fabrizio; Lander Team; Boehnhardt, Hermann; Bibring, Jean-Pierre; IDS Team; Gruen, Eberhard; Fulchignoni, Marcello; Weissman, Paul; Project Scientist Team; Taylor, Matt; Buratti, Bonnie; Altobelli, Nicolas; Choukroun, Mathieu; Ground-Based Observations Team; Snodgrass, Colin

    2016-10-01

    The Rosetta mission has been taking measurements of its target comet Comet 67P/Churyumov-Gerasimenko since early 2014 and will complete operations at the end of September 2016. The mission Science Management Plan, in 1994, laid out the the prime goals and themes of the mission. These five themes were: 1) To study the global characterisation of the Nuclues, the determination of the dynamics properties , surface morpholy and composition of the comet. 2) Examination of the Chemical, Mineralogical and isotopic compositions of volatiles and refractories in a cometary nucleus.3) Physical interrelation of volatile and refractories in a cometary nucleus4) Study the development of cometary activity and the process in the surface layer of the nucleus and in the inner coma5) The origins of comets, the relationship between cometary and interstellar material and the implications for the origin of the solar system,To cover all aspects of the Rosetta mission in this special Show case session, this abstracts is one of 5, with this particular presentation focusing on theme 3, in particular on a) The dust-to-gas ratio; b) distributed sources of volatiles; c) seasonal evolution of the dust size distribution.a) The dust-to-gas ratio has been provided by coma observations measuring the gas and dust loss rates from the nucleus surface. The ratio of these two loss rates provides a lower limit of the dust-to-gas ratio at the nucleus surface, since it does not take into account the largest chunks unable to leave the nucleus, or falling back due to the dominant gravity. We review the value inferred so far, its time evolution, and new techniques to directly measure it in the nucleus.b) Evidences offered by Rosetta observations of gas sublimating from dust particles are up to now faint. We report the few available observations and an estimate of the probable average water content in dust particles inferred by 3D gas-dynamical codes of 67P coma.c) The dust-size distribution tunes the sizes

  12. Brackett Gamma Imaging of the Nucleus of M83

    Science.gov (United States)

    Crosthwaite, L. P.; Turner, J. L.; Beck, S. C.; Meier, D. S.

    2004-12-01

    The gas-rich nucleus of barred spiral galaxy, M83, is a hotbed of star formation, with a total infrared luminosity of 4 X 109 Lo. We have observed the nucleus of M83 with the near infrared spectrometer, NIRSPEC, on Keck 2 to obtain high resolution Brγ recombination line spectra of the nucleus. Simultaneous imaging with the SCAM camera in a broadband K filter shows the position of the slit on the near-infrared galaxy. This allows us to map the nucleus with a continuum reference. The SCAM image shows a bright peak at the nucleus and a complex semi-circular arc of emission to the southwest. We stepped the 0.5'' X 24'' length slit in small declination increments to map a 20'' X 20'' region just west of the nucleus. Individual spectra were used to form a ra-dec-lambda cube and an integrated intensity map of Brγ . A total of 1.1 X 10-16 W m-2 of Brγ emission is detected in the map, in good agreement with previous low resolution observations (Turner, Ho, & Beck 1987, ApJ, 313, 644). This is not corrected for extinction within the molecular clouds in M83 or to the nebulae themselves and is therefore a lower limit to the true Brγ flux. Extinction is estimated to be at least a magnitude in the near-IR as measured in larger (4'') beams (Turner et al.) The bulk of the Brγ emission extends along the northern portion of the near-IR continuum semi-circle. Twenty percent of the total Brγ emission comes from single a 3'' (FWHM) source located 5'' west of the near-IR nucleus. The complementary NIRSPEC Brα data we have obtained will eventually allow us to evaluate the near-IR extinction on subarcsecond sizescales and obtain an extinction-corrected estimate of the Lyman continuum rate and therefore the number of ionizing stars.

  13. Subthalamic nucleus stimulation in severe obsessive-compulsive disorder.

    Science.gov (United States)

    Mallet, Luc; Polosan, Mircea; Jaafari, Nematollah; Baup, Nicolas; Welter, Marie-Laure; Fontaine, Denys; du Montcel, Sophie Tezenas; Yelnik, Jérôme; Chéreau, Isabelle; Arbus, Christophe; Raoul, Sylvie; Aouizerate, Bruno; Damier, Philippe; Chabardès, Stephan; Czernecki, Virginie; Ardouin, Claire; Krebs, Marie-Odile; Bardinet, Eric; Chaynes, Patrick; Burbaud, Pierre; Cornu, Philippe; Derost, Philippe; Bougerol, Thierry; Bataille, Benoit; Mattei, Vianney; Dormont, Didier; Devaux, Bertrand; Vérin, Marc; Houeto, Jean-Luc; Pollak, Pierre; Benabid, Alim-Louis; Agid, Yves; Krack, Paul; Millet, Bruno; Pelissolo, Antoine

    2008-11-13

    Severe, refractory obsessive-compulsive disorder (OCD) is a disabling condition. Stimulation of the subthalamic nucleus, a procedure that is already validated for the treatment of movement disorders, has been proposed as a therapeutic option. In this 10-month, crossover, double-blind, multicenter study assessing the efficacy and safety of stimulation of the subthalamic nucleus, we randomly assigned eight patients with highly refractory OCD to undergo active stimulation of the subthalamic nucleus followed by sham stimulation and eight to undergo sham stimulation followed by active stimulation. The primary outcome measure was the severity of OCD, as assessed by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), at the end of two 3-month periods. General psychopathologic findings, functioning, and tolerance were assessed with the use of standardized psychiatric scales, the Global Assessment of Functioning (GAF) scale, and neuropsychological tests. After active stimulation of the subthalamic nucleus, the Y-BOCS score (on a scale from 0 to 40, with lower scores indicating less severe symptoms) was significantly lower than the score after sham stimulation (mean [+/-SD], 19+/-8 vs. 28+/-7; P=0.01), and the GAF score (on a scale from 1 to 90, with higher scores indicating higher levels of functioning) was significantly higher (56+/-14 vs. 43+/-8, P=0.005). The ratings of neuropsychological measures, depression, and anxiety were not modified by stimulation. There were 15 serious adverse events overall, including 1 intracerebral hemorrhage and 2 infections; there were also 23 nonserious adverse events. These preliminary findings suggest that stimulation of the subthalamic nucleus may reduce the symptoms of severe forms of OCD but is associated with a substantial risk of serious adverse events. (ClinicalTrials.gov number, NCT00169377.) 2008 Massachusetts Medical Society

  14. Structures and functions in the crowded nucleus: new biophysical insights

    Directory of Open Access Journals (Sweden)

    Ronald eHancock

    2014-09-01

    Full Text Available Concepts and methods from the physical sciences have catalysed remarkable progress in understanding the cell nucleus in recent years. To share this excitement with physicists and encourage their interest in this field, this review offers an overview of how the physics which underlies structures and functions in the nucleus is becoming more clear thanks to methods which have been developed to simulate and study macromolecules, polymers, and colloids. The environment in the nucleus is very crowded with macromolecules, making entropic (depletion forces major determinants of interactions. Simulation and experiments are consistent with their key role in forming membraneless compartments such as nucleoli, PML and Cajal bodies, and discrete territories for chromosomes. The chromosomes, giant linear polyelectrolyte polymers, exist in vivo in a state like a polymer melt. Looped conformations are predicted in crowded conditions, and have been confirmed experimentally and are central to the regulation of gene expression. Polymer theory has revealed how the chromosomes are so highly compacted in the nucleus, forming a crumpled globule with fractal properties which avoids knots and entanglements in DNA while allowing facile accessibility for its replication and transcription. Entropic repulsion between looped polymers can explain the confinement of each chromosome to a discrete region of the nucleus. Crowding and looping are predicted to facilitate finding the specific targets of factors which modulate activities of DNA. Simulation shows that entropic effects contribute to finding and repairing potentially lethal double-strand breaks in DNA by increasing the mobility of the broken ends, favouring their juxtaposition for repair. Signaling pathways are strongly influenced by crowding, which favours a processive mode of response (consecutive reactions without releasing substrates. This new information contributes to understanding the sometimes counter

  15. Neuropathological changes in the nucleus basalis in schizophrenia.

    Science.gov (United States)

    Williams, M R; Marsh, R; Macdonald, C D; Jain, J; Pearce, R K B; Hirsch, S R; Ansorge, O; Gentleman, S M; Maier, M

    2013-09-01

    The nucleus basalis has not been examined in detail in severe mental illness. Several studies have demonstrated decreases in glia and glial markers in the cerebral cortex in schizophrenia, familial bipolar disorder and recurrent depression. Changes in neocortical neuron size and shape have also been reported. The nucleus basalis is a collection of large cholinergic neurons in the basal forebrain receiving information from the midbrain and limbic system, projecting to the cortex and involved with attention, learning and memory, and receives regulation from serotonergic inputs. Forty-one cases aged 41-60 years with schizophrenia or major depressive disorder with age-matched controls were collected. Formalin-fixed paraffin-embedded coronal nucleus basalis sections were histologically stained for oligodendrocyte identification with cresyl-haematoxylin counterstain, for neuroarchitecture with differentiated cresyl violet stain and astrocytes were detected by glial fibrillary acid protein immunohistochemistry. Cell density and neuroarchitecture were measured using Image Pro Plus. There were larger NB oval neuron soma in the combined schizophrenia and major depression disorder groups (p = 0.038), with no significant change between controls and schizophrenia and major depression disorder separately. There is a significant reduction in oligodendrocyte density (p = 0.038) in the nucleus basalis in schizophrenia. The ratio of gemistocytic to fibrillary astrocytes showed a greater proportion of the former in schizophrenia (18.1 %) and major depressive disorder (39.9 %) than in controls (7.9 %). These results suggest glial cell abnormalities in the nucleus basalis in schizophrenia possibly leading to cortical-limbic disturbance and subcortical dysfunction.

  16. Structures and functions in the crowded nucleus: new biophysical insights

    Science.gov (United States)

    Hancock, Ronald

    2014-09-01

    Concepts and methods from the physical sciences have catalysed remarkable progress in understanding the cell nucleus in recent years. To share this excitement with physicists and encourage their interest in this field, this review offers an overview of how the physics which underlies structures and functions in the nucleus is becoming more clear thanks to methods which have been developed to simulate and study macromolecules, polymers, and colloids. The environment in the nucleus is very crowded with macromolecules, making entropic (depletion) forces major determinants of interactions. Simulation and experiments are consistent with their key role in forming membraneless compartments such as nucleoli, PML and Cajal bodies, and discrete "territories" for chromosomes. The chromosomes, giant linear polyelectrolyte polymers, exist in vivo in a state like a polymer melt. Looped conformations are predicted in crowded conditions, and have been confirmed experimentally and are central to the regulation of gene expression. Polymer theory has revealed how the chromosomes are so highly compacted in the nucleus, forming a "crumpled globule" with fractal properties which avoids knots and entanglements in DNA while allowing facile accessibility for its replication and transcription. Entropic repulsion between looped polymers can explain the confinement of each chromosome to a discrete region of the nucleus. Crowding and looping are predicted to facilitate finding the specific targets of factors which modulate activities of DNA. Simulation shows that entropic effects contribute to finding and repairing potentially lethal double-strand breaks in DNA by increasing the mobility of the broken ends, favouring their juxtaposition for repair. Signaling pathways are strongly influenced by crowding, which favours a processive mode of response (consecutive reactions without releasing substrates). This new information contributes to understanding the sometimes counter-intuitive consequences.

  17. Influence of ionizing radiation on nucleus 24 cochlear implants.

    Science.gov (United States)

    Klenzner, T; Knapp, F; Röhner, F; von Wallenberg, E; Mauch, H; Pedersen, P; Aschendorff, A; Laszig, R; Lutterbach, J

    2005-07-01

    To evaluate the influence of conventional or hyperfractionated radiotherapy on Nucleus CI24M or CI24R(CS) implant systems. As a consequence of more than 70,000 cochlear implant recipients worldwide, the potential need for radiotherapy is an issue requiring consideration by both implantees and implantation centers. Conditions requiring radiotherapy of the head may include head, neck, or brain tumors. The study examines the effect of ionizing radiation on cochlear implant function. The implanted devices examined were the Nucleus CI24M and Nucleus CI24R(CS). In a modeled study, two implants of each type were treated with fraction schemes most frequently used in clinical routine (e.g., conventional fractionation [total dose, 120 Gy] and hyperfractionation [total dose, 116 Gy]). Parameters quantified were the implant output amplitude changes at high and low current level (current levels 255 and 100, respectively), the charge balance of the biphasic pulse, and the accuracy of the impedance telemetry function. Within the clinically relevant dose range (< 80 Gy), implant function in all four devices was normal. Failure occurred in one Nucleus CI24R(CS) device treated with hyperfractionation. A dramatic drop in the output amplitude at 106 Gy was observed, and the impedance measurement failed at a total dose of 111 Gy. The results suggest that conventional or hyperfractionated radiotherapy can be applied safely at Nucleus CI24M or CI24R(CS) implant systems in a patient-like setting. Therefore, the authors propose that the results of the study can be applicable in clinical practice.

  18. ARGININE VASOPRESSIN GENE EXPRESSION IN SUPRAOPTIC NUCLEUS AND PARAVENTRICULAR NUCLEUS OF HYPOTHALAMOUS FOLLOWING CEREBRAL ISCHEMIA AND REPERFUSION

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Background. Our previous studies indicated that the increased arginine vasopressin(AVP) in ischemic brain regions of gerbils could exacerbate the ischemic brain edema. This experiments is further clarify the relation between AVP and cerebral ischemia at the molecular level. Methods. The contents of AVP, AVP mRNA, AVP immunoreactive(ir) neurons in supraoptic nucleus(SON)and paraventricular nucleus(PVN) after cerebral ischemia and reperfusion were respectively determined by radioim-munoassay(RIA), immunocytochemistry( Ⅱ C), situ hybridization and computed image pattem analysis. Results. The contents of AVP in SON, PVN were increased, and the AVP ir positive neurons in SON and PVN were also significantly increased as compared with the controls after ischemia and reperfusion. And there were very light staining of AVP ir positive neurons in the other brain areas such as suprachiasmatic nucleus (SC) and periven-tricular hypothalamic nucleus (PE), but these have no significant changes as compared with the controls. During dif-ferent periods of cerebral ischemia (30~ 120 min) and reperfusion (30 min), AVP mRNA expression in SON and PVN were more markedly increased than the controls. Condusions. The transcription of AVP gene elevated, then promoting synthesis and release of AVP in SON,PVN. Under the specific condition of cerebral ischemia and repeffusion, the activity and contents of central AVP in-creased abnormally is one of the important factors which causes ischemia brain damage.

  19. Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

    National Research Council Canada - National Science Library

    Nakazawa, Naotaka; Sathe, Aneesh R; Shivashankar, G. V; Sheetz, Michael P

    2016-01-01

    ...) between FAs and the nucleus depends on matrix mechanics. In particular, on soft surfaces or after the loss of force, FHL2 moves from FAs into the nucleus and concentrates at RNA polymerase (Pol...

  20. Preservation of the nucleus X-pelvic floor motosystem in amyotrophic lateral sclerosis

    DEFF Research Database (Denmark)

    Schrøder, H D; Reske-Nielsen, E

    1984-01-01

    Fourteen cases of amyotrophic lateral sclerosis (ALS) were investigated neuropathologically, emphazising the sacral spinal cord which contains Onuf's nucleus X. The nucleus innervates the pelvic sphincters. In two cases, small striated pelvic muscles were studied. No changes characteristic of ALS...

  1. Functional identification of central afferent projections conveying information of acute "stress" to the hypothalamic paraventricular nucleus

    DEFF Research Database (Denmark)

    Larsen, P.J.; Mikkelsen, J.D.

    1995-01-01

    c-fos, corticotropin-releasing factor, neurosecretory neurons, paraventricular nucleus, transcription factors, neuroendocrinology, cholera toxin subunit B, retrograde tracing......c-fos, corticotropin-releasing factor, neurosecretory neurons, paraventricular nucleus, transcription factors, neuroendocrinology, cholera toxin subunit B, retrograde tracing...

  2. Projections from the raphe nuclei to the suprachiasmatic nucleus of the rat

    DEFF Research Database (Denmark)

    Hay-Schmidt, Anders; Vrang, N.; Larsen, P.J.

    2003-01-01

    Hypothalamus, Circadian rhythm, Serotonin, Nucleus, Neuronal connections, Phaseolus vulgaris-leucoagglutinin (PHA-L), Cholera toxin (ChB)......Hypothalamus, Circadian rhythm, Serotonin, Nucleus, Neuronal connections, Phaseolus vulgaris-leucoagglutinin (PHA-L), Cholera toxin (ChB)...

  3. Responses of primate caudal parabrachial nucleus and Kolliker-fuse nucleus neurons to whole body rotation

    Science.gov (United States)

    Balaban, Carey D.; McGee, David M.; Zhou, Jianxun; Scudder, Charles A.

    2002-01-01

    The caudal aspect of the parabrachial (PBN) and Kolliker-Fuse (KF) nuclei receive vestibular nuclear and visceral afferent information and are connected reciprocally with the spinal cord, hypothalamus, amygdala, and limbic cortex. Hence, they may be important sites of vestibulo-visceral integration, particularly for the development of affective responses to gravitoinertial challenges. Extracellular recordings were made from caudal PBN cells in three alert, adult female Macaca nemestrina through an implanted chamber. Sinusoidal and position trapezoid angular whole body rotation was delivered in yaw, roll, pitch, and vertical semicircular canal planes. Sites were confirmed histologically. Units that responded during rotation were located in lateral and medial PBN and KF caudal to the trochlear nerve at sites that were confirmed anatomically to receive superior vestibular nucleus afferents. Responses to whole-body angular rotation were modeled as a sum of three signals: angular velocity, a leaky integration of angular velocity, and vertical position. All neurons displayed angular velocity and integrated angular velocity sensitivity, but only 60% of the neurons were position-sensitive. These responses to vertical rotation could display symmetric, asymmetric, or fully rectified cosinusoidal spatial tuning about a best orientation in different cells. The spatial properties of velocity and integrated velocity and position responses were independent for all position-sensitive neurons; the angular velocity and integrated angular velocity signals showed independent spatial tuning in the position-insensitive neurons. Individual units showed one of three different orientations of their excitatory axis of velocity rotation sensitivity: vertical-plane-only responses, positive elevation responses (vertical plane plus ipsilateral yaw), and negative elevation axis responses (vertical plane plus negative yaw). The interactions between the velocity and integrated velocity components

  4. Nucleus downscaling in mouse embryos is regulated by cooperative developmental and geometric programs

    OpenAIRE

    Elina Tsichlaki; Greg FitzHarris

    2016-01-01

    Maintaining appropriate nucleus size is important for cell health, but the mechanisms by which this is achieved are poorly understood. Controlling nucleus size is a particular challenge in early development, where the nucleus must downscale in size with progressive reductive cell divisions. Here we use live and fixed imaging, micromanipulation approaches, and small molecule analyses during preimplantation mouse development to probe the mechanisms by which nucleus size is determined. We find a...

  5. File list: NoD.Neu.05.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  9. File list: InP.Neu.20.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  10. File list: His.Neu.20.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  11. File list: His.Neu.50.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  14. File list: InP.Neu.50.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  18. File list: Unc.Neu.50.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  19. File list: Unc.Neu.10.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  20. File list: Pol.Neu.10.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  1. File list: InP.Neu.05.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  3. File list: His.Neu.10.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  4. File list: Pol.Neu.50.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  5. File list: Oth.Neu.20.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  6. File list: ALL.Neu.20.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  7. File list: NoD.Neu.20.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  8. File list: NoD.Neu.50.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  9. File list: His.Neu.05.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  10. File list: Oth.Neu.50.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  11. File list: Pol.Neu.05.AllAg.Nucleus_Accumbens [Chip-atlas[Archive

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  12. File list: His.Neu.50.AllAg.Caudate_Nucleus [Chip-atlas[Archive

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  13. File list: ALL.Neu.10.AllAg.Caudate_Nucleus [Chip-atlas[Archive

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  14. File list: His.Neu.20.AllAg.Caudate_Nucleus [Chip-atlas[Archive

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  18. File list: His.Neu.10.AllAg.Caudate_Nucleus [Chip-atlas[Archive

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  19. File list: ALL.Neu.50.AllAg.Caudate_Nucleus [Chip-atlas[Archive

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  20. Experiments on parity violation in the compound nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, J.D.

    1996-09-01

    Results from experiments that measure parity-violating longitudinal asymmetries in the scattering of epithermal neutrons from compound-nuclear resonances at the Manuel Lujan Neutron Scattering Center at Los Alamos are discussed. Parity non-conserving asymmetries have been observed for many p-wave resonances in a single target. Measurements were performed on several nuclei in the mass region of A-100 and A-230. The statistical model of the compound nucleus provides a theoretical basis for extracting mean-squared matrix elements from the experimental asymmetry data, and for interpreting the mean-squared matrix elements. The constraints on the weak meson-exchange couplings calculated from the compound-nucleus asymmetry data agree qualitatively with the results from few-body and light-nuclei experiments. For all nuclei but {sup 232}Th measured asymmetries have random signs. For {sup 232}Th eight of eight measured asymmetries are positive. This phenomenon is discussed in terms or doorway models.

  1. Determination of the {\\eta}'-nucleus optical potential

    CERN Document Server

    Nanova, M; Paryev, E Ya; Bayadilov, D; Bantes, B; Beck, R; Beloglazov, Y A; Böse, S; Brinkmann, K -T; Challand, Th; Crede, V; Dahlke, T; Dietz, F; Drexler, P; Eberhardt, H; Elsner, D; Ewald, R; Fornet-Ponse, K; Friedrich, S; Frommberger, F; Funke, Ch; Gottschall, M; Gridnev, A; Grüner, M; Gutz, E; Hammann, Ch; Hammann, D; Hannappel, J; Hartmann, J; Hillert, W; Hoffmeister, P; Honisch, Ch; Jaegle, I; Kaiser, D; Kalinowsky, H; Kammer, S; Keshelashvili, I; Kleber, V; Klein, F; Klempt, E; Krusche, B; Lang, M; Lopatin, I V; Maghrbi, Y; Makonyi, K; Müller, J; Odenthal, T; Piontek, D; Schaepe, S; Schmidt, Ch; Schmieden, H; Schmitz, R; Seifen, T; Thiel, A; Thoma, U; van Pee, H; Walther, D; Wendel, Ch; Wiedner, U; Wilson, A; Winnebeck, A; Zenke, F

    2013-01-01

    The excitation function and momentum distribution of $\\eta^\\prime$ mesons have been measured in photon induced reactions on $^{12}{}$C in the energy range of 1250-2600 MeV. The experiment was performed with tagged photon beams from the ELSA electron accelerator using the Crystal Barrel and TAPS detectors. The data are compared to model calculations to extract information on the sign and magnitude of the real part of the $\\eta^\\prime$-nucleus potential. Within the model, the comparison indicates an attractive potential of -($37 \\pm 10(stat)\\pm10(syst)$) MeV depth at normal nuclear matter density. Since the modulus of this depth is larger than the modulus of the imaginary part of the $\\eta^\\prime$-nucleus potential of -($10\\pm2.5$) MeV, determined by transparency ratio measurements, a search for resolved $\\eta^\\prime$-bound states appears promising.

  2. Leading Neutrons From Polarized Proton-Nucleus Collisions

    CERN Document Server

    Kopeliovich, B Z; Schmidt, Ivan

    2016-01-01

    Leading neutron production on protons is known to be subject to strong absorptive corrections, which have been under debate for a long time. On nuclear targets these corrections are significantly enhanced and push the partial cross sections of neutron production to the very periphery of the nucleus. As a result, the A-dependences of inclusive and diffractive neutron production turn out to be similar. The mechanism of \\pi-a_1 interference, which successfully explained the observed single-spin asymmetry of neutrons in polarized pp interactions, is extended here to polarized pA collisions. Corrected for nuclear effects it explains well the magnitude and sign of the asymmetry A_N observed in inelastic events, resulting in a violent break up of the nucleus. However the excessive magnitude of A_N observed in the diffractive sample, remains a challenge.

  3. Neutrino-nucleus interactions at the LBNF near detector

    Energy Technology Data Exchange (ETDEWEB)

    Mosel, Ulrich [Institut fuer Theoretische Physik, Universitaet Giessen, D-35392 Giessen (Germany)

    2015-10-15

    The reaction mechanisms for neutrino interactions with an {sup 40}Ar nucleus with the LBNF flux are calculated with the Giessen-Boltzmann-Uehling-Uhlenbeck (GiBUU) transport-theoretical implementation of these interactions. Quasielastic scattering, many-body effects, pion production and absorption and Deep Inelastic Scattering are discussed; they all play a role at the LBNF energies and are experimentally entangled with each other. Quasielastic scattering makes up for only about 1/3 of the total cross section whereas pion production channels make up about 2/3 of the total. This underlines the need for a consistent description of the neutrino-nucleus reaction that treats all channels on an equal, consistent footing. The results discussed here can also serve as useful guideposts for the Intermediate Neutrino Program.

  4. Neutrino-Nucleus Interactions at the LBNF Near Detector

    CERN Document Server

    Mosel, Ulrich

    2015-01-01

    The reaction mechanisms for neutrino interactions with an $^{40}Ar$ nucleus with the LBNF flux are calculated with the Giessen-Boltzmann-Uehling-Uhlenbeck (GiBUU) transport-theoretical implementation of these interactions. Quasielastic scattering, many-body effects, pion production and absorption and Deep Inelastic Scattering are discussed; they all play a role at the LBNF energies and are experimentally entangled with each other. Quasielastic scattering makes up for only about 1/3 of the total cross section whereas pion production channels make up about 2/3 of the total. This underlines the need for a consistent description of the neutrino-nucleus reaction that treats all channels on an equal, consistent footing. The results discussed here can also serve as useful guideposts for the Intermediate Neutrino Program.

  5. Neutral current neutrino-nucleus interactions at intermediate energies

    CERN Document Server

    Leitner, T; Mosel, U

    2006-01-01

    We have extended our model for charged current neutrino-nucleus interactions to neutral current reactions. For the elementary neutrino-nucleon interaction, we take into account quasielastic scattering, Delta excitation and the excitation of the resonances in the second resonance region. Our model for the neutrino-nucleus collisions includes in-medium effects such as Fermi motion, Pauli blocking, nuclear binding, and final-state interactions. They are implemented by means of the Giessen Boltzmann-Uehling-Uhlenbeck (GiBUU) coupled-channel transport model. This allows us to study exclusive channels, namely pion production and nucleon knockout. We find that final-state interactions modify considerably the distributions through rescattering, charge-exchange and absorption. Side-feeding induced by charge-exchange scattering is important in both cases. In the case of pions, there is a strong absorption associated with the in-medium pionless decay modes of the Delta, while nucleon knockout exhibits a considerable enh...

  6. Exporting RNA from the nucleus to the cytoplasm.

    Science.gov (United States)

    Köhler, Alwin; Hurt, Ed

    2007-10-01

    The transport of RNA molecules from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes via mobile export receptors. Small RNAs (such as tRNAs and microRNAs) follow relatively simple export routes by binding directly to export receptors. Large RNAs (such as ribosomal RNAs and mRNAs) assemble into complicated ribonucleoprotein (RNP) particles and recruit their exporters via class-specific adaptor proteins. Export of mRNAs is unique as it is extensively coupled to transcription (in yeast) and splicing (in metazoa). Understanding the mechanisms that connect RNP formation with export is a major challenge in the field.

  7. Gamma-ray spectroscopy of the nucleus {sup 139}Ce

    Energy Technology Data Exchange (ETDEWEB)

    Bucurescu, D.; Cata-Danil, G.; Cata-Danil, I.; Ivascu, M.; Marginean, N.; Marginean, R.; Mihailescu, L.C.; Rusu, C.; Suliman, G. [Horia Hulubei National Institute of Physics and Nuclear Engineering, P.O. Box MG-6, Bucharest (Romania)

    2006-03-15

    Gamma-ray coincidence techniques are used to determine new level structures in the N=81 nucleus {sup 139}Ce, at low spins and excitation energies with the {sup 139}La(p,n{gamma}) reaction at 5.0 and 6.0 MeV incident energy, and at high spins with the {sup 130}Te({sup 12}C,3n{gamma}) reaction at 50.5 MeV, respectively. Lifetime determinations are also made in the (p,n{gamma}) reaction with the centroid DSA method. The observed level structures are discussed by comparison with existing calculations and with those in the neighbouring nucleus {sup 140}Ce. (orig.)

  8. Shape transitions far from stability: The nucleus {sup 58}Cr

    Energy Technology Data Exchange (ETDEWEB)

    Marginean, N. [INFN, Laboratori Nazionali di Legnaro, Legnaro (Italy) and National Institute for Physics and Nuclear Engineering, Bucharest (Romania)]. E-mail: nicolae.marginean@lnl.infn.it; Lenzi, S.M. [Dipartimento di Fisica and INFN, Padova (Italy); Gadea, A. [INFN, Laboratori Nazionali di Legnaro, Legnaro (Italy)] (and others)

    2006-02-23

    Excited states up to I{sup {pi}}=8{sup +} in the neutron-rich nucleus {sup 58}Cr have been identified by using a new experimental setup composed of the large acceptance magnetic spectrometer PRISMA and the highly efficient {gamma}-detector array CLARA. Interestingly, the excitation energy sequence of the ground-state band follows the one expected by the E(5) dynamical symmetry for a nucleus at the critical point of the shape phase transition from a spherical vibrator (U(5)) to a {gamma}-soft rotor (O(6)). For the first time, in the same physical system, large scale shell-model calculations in the full fp shell are compared to the E(5) analytical model results and to the Interacting Boson Model. The theoretical results are in excellent agreement with the present data.

  9. Efficient And Portable SDR Waveform Development: The Nucleus Concept

    CERN Document Server

    Ramakrishnan, Venkatesh; Kempf, Torsten; Kammler, David; Ascheid, Gerd; Meyr, Heinrich; Adrat, Marc; Antweiler, Markus

    2009-01-01

    Future wireless communication systems should be flexible to support different waveforms (WFs) and be cognitive to sense the environment and tune themselves. This has lead to tremendous interest in software defined radios (SDRs). Constraints like throughput, latency and low energy demand high implementation efficiency. The tradeoff of going for a highly efficient implementation is the increase of porting effort to a new hardware (HW) platform. In this paper, we propose a novel concept for WF development, the Nucleus concept, that exploits the common structure in various wireless signal processing algorithms and provides a way for efficient and portable implementation. Tool assisted WF mapping and exploration is done efficiently by propagating the implementation and interface properties of Nuclei. The Nucleus concept aims at providing software flexibility with high level programmability, but at the same time limiting HW flexibility to maximize area and energy efficiency.

  10. ηproduction in proton-nucleus collisions near threshold

    Institute of Scientific and Technical Information of China (English)

    YANG You-Chang; CHEN Hong; JIANG Huan-Qing

    2008-01-01

    The η-meson production in proton-nucleus(pA)collisions near threshold is studied within a relativistic meson-exchange model.The primary production amplitude is presented in the distorted-wave impulse approximation for the nucleus with isospin 0 or [1]by assuming that N*(1535)is excited via a meson exchange and then decays into η and nucleon pair(ηN).Taking 18O and 12C nuclei as examples,we evaluate the production cross sections as a function of the incident proton energy,and analyze the effects of nuclear medium and various meson-exchange contributions.Finally we discuss implications for further experimental studies at the Cooling Storage Ring(CSR)in Lanzhou.

  11. Relativistic Spin-Isospin Dependent Response Function of Nucleus

    Institute of Scientific and Technical Information of China (English)

    LIU Liang-Gang; CHEN Wei; AI Bao-Quan; ZHENG Xiao-Ping; Masahiro Nakano

    2000-01-01

    A full relativistic formalism is employed to derive the relativistic particle-hole and delta-hole excitation polariza tion insertion of pion propagator in nuclear matter. The spin-isospin-dependent response function of nucleus at high energy-momentum transfer is calculated with the nuclear matter approximation. The short range correlation effect, two-nucleon absorption and nucleus form factor effects are included in the calculation. The position and width of the resonance peak of the spin-isospin mode are reproduced and found to be coincident with experiment data. The position of the peak and its width is sensitive to Landau-Migdal parameter g' which is about 0.6.

  12. Triple F - A Comet Nucleus Sample Return Mission

    Science.gov (United States)

    Kueppers, Michael; Keller, H. U.; Kuehrt, E.; A'Hearn, M. F.; Altwegg, K.; Bertrand, R.; Busemann, H.; Capria, M. T.; Colangeli, L.; Davidsson, B.; hide

    2008-01-01

    The Triple F (Fresh From the Fridge) mission, a Comet Nucleus Sample Return, has been proposed to ESA's Cosmic Vision program. A sample return from a comet enables us to reach the ultimate goal of cometary research. Since comets are the least processed bodies in the solar system, the proposal goes far beyond cometary science topics (like the explanation of cometary activity) and delivers invaluable information about the formation of the solar system and the interstellar molecular cloud from which it formed. The proposed mission would extract three sample cores of the upper 50 cm from three locations on a cometary nucleus and return them cooled to Earth for analysis in the laboratory. The simple mission concept with a touch-andgo sampling by a single spacecraft was proposed as an M-class mission in collaboration with the Russian space agency ROSCOSMOS.

  13. Proton emission from an oblate nucleus {sup 151}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Procter, M.G., E-mail: mark.procter@postgrad.manchester.ac.uk [School of Physics and Astronomy, Schuster Laboratory, The University of Manchester, Manchester M13 9PL (United Kingdom); Cullen, D.M.; Taylor, M.J.; Alharshan, G.A. [School of Physics and Astronomy, Schuster Laboratory, The University of Manchester, Manchester M13 9PL (United Kingdom); Ferreira, L.S. [Centro de Física das Interacções Fundamentais, Departamento de Física, Instituto Superior Tecnico, Avenida Rovisco Pais, P1049-001 Lisbon (Portugal); Maglione, E. [Dipartimento di Fisica “G. Galilei”, Istituto Nazionale di Fisica Nucleare, Via Marzolo 8, I-3513, Padova (Italy); Auranen, K.; Grahn, T.; Greenlees, P.T.; Jakobsson, U.; Julin, R.; Herzáň, A.; Konki, J.; Leino, M. [Department of Physics, University of Jyväskylä, FIN-40014 Jyväskylä (Finland); Pakarinen, J. [Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Partanen, J. [Institut für Kernphysik, Universität zu Köln, D-50937, Köln (Germany); Peura, P.; Rahkila, P.; Ruotsalainen, P.; Sandzelius, M. [Department of Physics, University of Jyväskylä, FIN-40014 Jyväskylä (Finland); and others

    2013-08-09

    Excited states in the proton-unbound nucleus {sup 151}Lu have been established using γ-ray coincidence techniques. The lifetime of the first excited state above the proton-emitting ground state has been measured using the recoil-distance Doppler-shift method combined with recoil-decay tagging. The experimental level scheme and extracted lifetime have been compared with state-of-the-art theoretical calculations based upon a non-adiabatic deformed Woods–Saxon potential. This comparison suggests that the proton-emitting ground state in {sup 151}Lu is mildly oblate with a deformation β=−0.11{sub −0.05}{sup +0.02} and represents the best evidence to date for proton emission from an oblate nucleus.

  14. Pairing reentrance in warm rotating $^{104}$Pd nucleus

    CERN Document Server

    Hung, N Quang; Agrawal, B K; Datar, V M; Mitra, A; Chakrabarty, D R

    2015-01-01

    Pairing reentrance phenomenon in the warm rotating $^{104}$Pd nucleus is studied within the Bardeen-Cooper-Schrieffer (BCS)-based approach (the FTBCS1). The theory takes into account the effect of quasiparticle number fluctuations on the pairing field at finite temperature and angular momentum within the pairing model plus noncollective rotation along the symmetry axis. The numerical calculations for the pairing gaps and nuclear level densities (NLD), of which an anomalous enhancement has been experimentally observed at low excitation energy $E^*$ and high angular momentum $J$, show that the pairing reentrance is seen in the behavior of pairing gap obtained within the FTBCS1 at low $E$ and high $J$. This leads to the enhancement of the FTBCS1 level densities, in good agreement with the experimental observation. This agreement indicates that the observed enhancement of the NLD might be the first experimental detection of the pairing reentrance in a finite nucleus.

  15. Charge, neutron, and weak size of the atomic nucleus

    CERN Document Server

    Hagen, G; Forssén, C; Jansen, G R; Nazarewicz, W; Papenbrock, T; Wendt, K A; Bacca, S; Barnea, N; Carlsson, B; Drischler, C; Hebeler, K; Hjorth-Jensen, M; Miorelli, M; Orlandini, G; Schwenk, A; Simonis, J

    2015-01-01

    What is the size of the atomic nucleus? This deceivably simple question is difficult to answer. While the electric charge distributions in atomic nuclei were measured accurately already half a century ago, our knowledge of the distribution of neutrons is still deficient. In addition to constraining the size of atomic nuclei, the neutron distribution also impacts the number of nuclei that can exist and the size of neutron stars. We present an ab initio calculation of the neutron distribution of the neutron-rich nucleus $^{48}$Ca. We show that the neutron skin (difference between radii of neutron and proton distributions) is significantly smaller than previously thought. We also make predictions for the electric dipole polarizability and the weak form factor; both quantities are currently targeted by precision measurements. Based on ab initio results for $^{48}$Ca, we provide a constraint on the size of a neutron star.

  16. The size-wise nucleus: nuclear volume control in eukaryotes.

    Science.gov (United States)

    Huber, Michael D; Gerace, Larry

    2007-11-19

    Eukaryotic cells have an "awareness" of their volume and organellar volumes, and maintain a nuclear size that is proportional to the total cell size. New studies in budding and fission yeast have examined the relationship between cell and nuclear volumes. It was found that the size of the nucleus remains proportional to cell size in a wide range of genetic backgrounds and growth conditions that alter cell volume and DNA content. Moreover, in multinucleated fission yeast cells, Neumann and Nurse (see p. 593 of this issue) found that the sizes of individual nuclei are controlled by the relative amount of cytoplasm surrounding each nucleus. These results highlight a role of the cytoplasm in nuclear size control.

  17. The identification of musical instruments through nucleus cochlear implants.

    Science.gov (United States)

    Grasmeder, M L; Lutman, M E

    2006-09-01

    In this study, self-reported ability to recognize musical instruments was investigated by means of a questionnaire, which was sent to a group of adult Nucleus cochlear implant users and a group of normally hearing subjects. In addition, spectrograms and electrodograms were produced and analysed for samples of music played on 10 different musical instruments. Self-reported ability to recognize some instruments was poor in the group of implant users, particularly for the saxophone, tuba and clarinet. Electrodograms showed that these instruments could only be identified using distorted spectral information or reduced temporal information. Other instruments, such as the drum and piano, could be identified using temporal information. Limited spectral resolution makes the recognition of musical instruments difficult for Nucleus implant users.

  18. $K^+$-nucleus potentials from $K^+$-nucleon amplitudes

    CERN Document Server

    Friedman, E

    2016-01-01

    Optical potentials for $K^+$-nucleus interactions are constructed from $K^+$-nucleon amplitudes using recently developed algorithm based on $K^+$-N kinematics in the nuclear medium. With the deep penetration of $K^+$ mesons into the nucleus at momenta below 800~MeV/c it is possible to test this approach with greater sensitivity than hitherto done with $K^-$ and pions. The energy-dependence of experimental reaction and total cross sections on nuclei is better reproduced with this approach compared to fixed-energy amplitudes. The inclusion of Pauli correlations in the medium also improves the agreement between calculation and experiment. The absolute scale of the cross sections is reproduced very well for $^6$Li but for C, Si and Ca calculated cross sections are (23$\\pm4$)\\% smaller than experiment, in agreement with earlier analyses. Two phenomenological models that produce such missing strength suggest that the imaginary part of the potential needs about 40\\% enhancement.

  19. K+-nucleus potentials from K+-nucleon amplitudes

    Science.gov (United States)

    Friedman, E.

    2016-10-01

    Optical potentials for K+-nucleus interactions are constructed from K+-nucleon amplitudes using recently developed algorithm based on K+-N kinematics in the nuclear medium. With the deep penetration of K+ mesons into the nucleus at momenta below 800 MeV / c it is possible to test this approach with greater sensitivity than hitherto done with K- and pions. The energy-dependence of experimental reaction and total cross sections on nuclei is better reproduced with this approach compared to fixed-energy amplitudes. The inclusion of Pauli correlations in the medium also improves the agreement between calculation and experiment. The absolute scale of the cross sections is reproduced very well for 6Li but for C, Si and Ca calculated cross sections are (23 ± 4)% smaller than experiment, in agreement with earlier analyses. Two phenomenological models that produce such missing strength suggest that the imaginary part of the potential needs about 40% enhancement.

  20. Electromagnetic properties of the Beryllium-11 nucleus in Halo EFT

    Directory of Open Access Journals (Sweden)

    Hammer H.-W.

    2010-04-01

    Full Text Available We compute electromagnetic properties of the Beryllium-11 nucleus using an effective field theory that exploits the separation of scales in this halo system. We fix the parameters of the EFT from measured data on levels and scattering lengths in the 10Be plus neutron system. We then obtain predictions for the B(E1 strength of the 1/2+ to 1/2− transition in the 11Be nucleus. We also compute the charge radius of the ground state of 11Be. Agreement with experiment within the expected accuracy of a leading-order computation in this EFT is obtained. We also indicate how higher-order corrections that affect both s-wave and p-wave 10 Be-neutron interactions will affect our results.

  1. NPY and VGF Immunoreactivity Increased in the Arcuate Nucleus, but Decreased in the Nucleus of the Tractus Solitarius, of Type-II Diabetic Patients

    OpenAIRE

    Nadia Saderi; Roberto Salgado-Delgado; Rafael Avendaño-Pradel; Maria del Carmen Basualdo; Gian-Luca Ferri; Laura Chávez-Macías; Juan E Olvera Roblera; Carolina Escobar; Buijs, Ruud M.

    2012-01-01

    Ample animal studies demonstrate that neuropeptides NPY and α-MSH expressed in Arcuate Nucleus and Nucleus of the Tractus Solitarius, modulate glucose homeostasis and food intake. In contrast is the absence of data validating these observations for human disease. Here we compare the post mortem immunoreactivity of the metabolic neuropeptides NPY, αMSH and VGF in the infundibular nucleus, and brainstem of 11 type-2 diabetic and 11 non-diabetic individuals. α-MSH, NPY and tyrosine hydroxylase i...

  2. The Cl-35/Cl-37 isotopic ratio in dense molecular clouds : HIFI observations of hydrogen chloride towards W3 A

    NARCIS (Netherlands)

    Cernicharo, J.; Goicoechea, J. R.; Daniel, F.; Agundez, M.; Caux, E.; de Graauw, T.; De Jonge, A.; Kester, D.; Leduc, H. G.; Steinmetz, E.; Stutzki, J.; Ward, J. S.

    2010-01-01

    We report on the detection with the HIFI instrument on board the Herschel satellite of the two hydrogen chloride isotopologues, (HCl)-Cl-35 and (HCl)-Cl-37, towards the massive star-forming region W3 A. The J = 1-0 line of both species was observed with receiver 1b of the HIFI instrument at similar

  3. Light and variable 37Cl/35Cl ratios in rocks from Gale Crater, Mars: Possible signature of perchlorate

    Science.gov (United States)

    Farley, K. A.; Martin, P.; Archer, P. D.; Atreya, S. K.; Conrad, P. G.; Eigenbrode, J. L.; Fairén, A. G.; Franz, H. B.; Freissinet, C.; Glavin, D. P.; Mahaffy, P. R.; Malespin, C.; Ming, D. W.; Navarro-Gonzalez, R.; Sutter, B.

    2016-03-01

    Cl isotope ratios measured on HCl thermally evolved from as-yet-unknown phases in sedimentary rocks and sand in Gale Crater provide unexpected insights to the Martian surficial Cl cycle. The seven samples yield δ37Cl values ranging from - 1 ± 25 ‰ to - 51 ± 5 ‰. Five analyses from two samples of the Sheepbed mudstone (Yellowknife Bay study area) are analytically indistinguishable with a mean δ37Cl of - 11 ± 7 ‰ (1 σ). In contrast, four mudstones/sandstones from the Kimberley and Pahrump study areas also yielded indistinguishable ratios, but with a mean δ37Cl of - 43 ± 6 ‰. The Rocknest sand deposit gave a highly uncertain δ37Cl value of - 7 ± 44 ‰. These light and highly variable δ37Cl values are unique among known solar system materials. Two endmember models are offered to account for these observations, and in both, perchlorate, with its extreme ability to fractionate Cl isotopes, is critical. In the first model, SAM is detecting HCl from an oxychlorine compound (e.g., perchlorate) produced from volcanic gas emissions by atmospheric chemical reactions. Similar reactions in Earth's atmosphere may be responsible for the isotopically lightest known Cl outside of this study, in perchlorate from the Atacama Desert. Some of the Gale Crater δ37Cl values are more negative than those in Atacama perchlorate, but because reaction mechanisms and associated fractionation factors are unknown, it is impossible to assess whether this difference is prohibitive. If the negative δ37Cl signal is produced in this fashion, the isotopic variability among samples could arise either from variations in the relative size of the reactant chloride and product perchlorate reservoirs, or from variations in the fraction of perchlorate reduced back to chloride after deposition. Such reduction strongly enriches 37Cl in the residual perchlorate. Perchlorate reduction alone offers an alternative endmember model that can explain the observed data if SAM measured HCl derived from chloride. In this model isotopically normal perchlorate produced by an unspecified mechanism is reduced to chloride. Depending on the relative size of the reduced reservoir, the integrated product chloride can vary in isotopic composition from - 70 ‰ in the first increment all the way to the starting composition if the perchlorate is fully reduced. Thus, variable degrees of perchlorate reduction can produce chloride with the appropriate δ37Cl range. Combination of the two endmember models, in which the perchlorate subject to post-deposition reduction is isotopically negative from atmospheric reactions, is also possible. Determination of the phase hosting the Cl measured by SAM, an oxychlorine compound or chloride, is critical for selecting between these models, and for developing implications of the results for the Mars surficial Cl cycle. At present it is not possible to conclusively establish which phase is responsible (possibly both), but limited evidence favors the conclusion that the measured Cl derives mostly from an oxychlorine compound.

  4. Isospin effects in elastic proton-nucleus scattering

    Science.gov (United States)

    Chinn, C. R.; Elster, Ch.; Thaler, R. M.

    1993-05-01

    Isovector effects in proton-nucleus elastic scattering at medium energies are studied. The accuracy of the Kerman-McManus-Thaler isospin averaging procedure is found to be very good for nuclei larger than 4He. Studies of 40Ca and 208Pb suggest that the surface neutrons may be pulled in somewhat relative to the protons, although uncertainties in the detailed applicability of the present truncation of the multiple scattering treatment render firm conclusions premature.

  5. Isospin effects in elastic proton-nucleus scattering

    Energy Technology Data Exchange (ETDEWEB)

    Chinn, C.R. (Service de Physique et Techniques Nucleaires, Centre d' Etudes de Bruyeres-le-Chatel, B.P. No. 12, 91680 Bruyeres-le-Chatel (France)); Elster, C. (Institute of Nuclear and Particle Physics and Department of Physics, Ohio University, Athens, Ohio 45701 (United States)); Thaler, R.M. (Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States) Case Western Reserve University, Cleveland, Ohio 44106 (United States))

    1993-05-01

    Isovector effects in proton-nucleus elastic scattering at medium energies are studied. The accuracy of the Kerman-McManus-Thaler isospin averaging procedure is found to be very good for nuclei larger than [sup 4]He. Studies of [sup 40]Ca and [sup 208]Pb suggest that the surface neutrons may be pulled in somewhat relative to the protons, although uncertainties in the detailed applicability of the present truncation of the multiple scattering treatment render firm conclusions premature.

  6. PHARMACOLOGIC TREATMENT OF HYPERALGESIA EXPERIMENTALLY INDUCED BY NUCLEUS PULPOSUS

    OpenAIRE

    de Souza Grava, André Luiz; Ferrari,Luiz Fernando; Parada, Carlos Amílcar; Defino, Helton Luiz Aparecido

    2015-01-01

    Objective: To evaluate the effect of anti-inflammatory drugs (dexamethasone, indomethacin, atenolol and indomethacin plus atenolol) and analgesic drugs (morphine) on hyperalgesia experimentally induced by the nucleus pulposus (NP) in contact with the L5 dorsal root ganglion (DRG). Methods: Thirty male Wistar rats of weights ranging from 220 to 250 g were used in the study. Hyperalgesia was induced by means of a fragment of NP removed from the sacrococcygeal region that was placed in contact w...

  7. Methods and compositions for targeting macromolecules into the nucleus

    Science.gov (United States)

    Chook, Yuh Min

    2013-06-25

    The present invention includes compositions, methods and kits for directing an agent across the nuclear membrane of a cell. The present invention includes a Karyopherin beta2 translocation motif in a polypeptide having a slightly positively charged region or a slightly hydrophobic region and one or more R/K/H-X.sub.(2-5)-P-Y motifs. The polypeptide targets the agent into the cell nucleus.

  8. {alpha}-nucleus potentials and photon-induced nucleosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Galaviz, D. E-mail: redondo@ikp.tu-darmstadt.de; Babilon, M.; Fueloep, Zs.; Gyuerky, Gy.; Hillier, R.; Mate, Z.; Mohr, P.; Rauscher, T.; Somorjai, E.; Zilges, A.; Zolnai, L

    2003-05-05

    New data for the {sup 112,124}Sn({alpha},{alpha}){sup 112,124}Sn reaction have been measured and are presently analyzed. Results of the {sup 112} Sn x {alpha} potential at the energy E{sub c.m.} {approx} 14 MeV are presented. The determination of this {alpha}-nucleus potential may allow a prediction of the {sup 112}Sn({alpha},{gamma}){sup 116}Te cross section.

  9. Theoretical Aspects of Coherent Elastic Neutrino Nucleus Scattering

    Science.gov (United States)

    McLaughlin, Gail

    2014-09-01

    We will discuss the physics potential of coherent elastic neutrino nucleus scattering. This standard model process has never been directly measured, although there are a number of experiments proposed at stopped pion/muon or reactor sites that could make such a first detection. Such a measurement opens up the possibility for a number of interesting physics probes. We will review these from a theoretical point of view, with a particular focus on the nuclear-neutron form factor.

  10. High-spin states in the {sup 97}Tc nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Bucurescu, D.; Cata-Danil, G.; Cata-Danil, I.; Ivascu, M.; Marginean, N.; Rusu, C.; Stroe, L.; Ur, C.A. [National Institute of Physics and Nuclear Engineering, P.O. Box MG-6, Bucharest 76900 (Romania); Gadea, A. [INFN, Laboratori Nazionali di Legnaro, Legnaro (Italy)

    2003-04-01

    High-spin states in the {sup 97}Tc nucleus have been studied by in-beam {gamma}-ray spectroscopy with the reaction {sup 82}Se({sup 19}F,4n{gamma}) at 68 MeV incident energy. Excited states have been observed up to about 8 MeV excitation and spin 43/2{Dirac_h}. The observed level scheme is compared with results of shell model calculations. (orig.)

  11. Decay of the N =126 , 213Fr nucleus

    Science.gov (United States)

    Pragati, Deo, A. Y.; Podolyák, Zs.; Walker, P. M.; Algora, A.; Rubio, B.; Agramunt, J.; Fraile, L. M.; Al-Dahan, N.; Alkhomashi, N.; Briz, J. A.; Aguado, M. E. Estevez; Farrelly, G.; Gelletly, W.; Herlert, A.; Köster, U.; Maira, A.

    2016-12-01

    γ rays following the EC/β+ and α decay of the N = 126, 213Fr nucleus have been observed at the CERN isotope separator on-line (ISOLDE) facility with the help of γ -ray and conversion-electron spectroscopy. These γ rays establish several hitherto unknown excited states in 213Rn. Also, five new α -decay branches from the 213Fr ground state have been discovered. Shell model calculations have been performed to understand the newly observed states in 213Rn.

  12. Nucleus-associated intermediate filaments from chicken erythrocytes

    OpenAIRE

    1980-01-01

    Chicken erythrocyte nuclei prepared by isolation in isotonic KCl and Nonidet P-40 detergent were found to contain numerous attached filaments with a mean diameter of 11.0 nm. In polypeptide content and solubility properties, they resembled the vimentin type of intermediate filament found in cells of mesenchymal origin. Examination of their association with the nucleus suggests that more than a simple membrane attachment is involved.

  13. How did nucleus and sexual reproduction come into being?

    OpenAIRE

    Ping Xie

    2016-01-01

    The origin of eukaryote is a fundamental, forbidding evolutionary puzzle, and the popular scenarios of eukaryogenesis are far from being clear. So far, there have been various theories (e.g., syntrophic model, autogenous model, viral eukaryogenesis model, exomembrane hypothesis), but few explain why. I observed that C-value (the amount of DNA contained within a haploid nucleus) increased by 3.5 orders of magnitude from prokaryote to eukaryotes, which is inconceivably close to the packing rati...

  14. Nucleus accumbens μ-opioid receptors mediate social reward

    OpenAIRE

    Trezza, Viviana; Damsteegt, Ruth; Achterberg, E J Marijke; Vanderschuren, Louk J. M. J

    2011-01-01

    Positive social interactions are essential for emotional well-being and proper behavioral development of young individuals. Here, we studied the neural underpinnings of social reward, by investigating the involvement of opioid neurotransmission in the nucleus accumbens (NAc) in social play behavior, a highly rewarding social interaction in adolescent rats. Intra-NAc infusion of morphine (0.05–0.1 μg) increased pinning and pouncing, characteristic elements of social play behavior in rats, and ...

  15. High-spin states in the {sup 96}Tc nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Bucurescu, D.; Cata-Danil, G.; Cata-Danil, I.; Ivascu, M.; Marginean, N.; Rusu, C.; Stroe, L.; Ur, C.A. [National Inst. of Physics and Nuclear Engineering, Bucharest (Romania); Gizon, A.; Gizon, J. [Inst. des Sciences Nucleaires, IN2P3-CNRS/UPJ, Grenoble (France); Nyako, B.; Timar, J.; Zolnai, L. [Inst. of Nuclear Research, Debrecen (Hungary); Boston, A.J.; Joss, D.T.; Paul, E.S.; Semple, A.T. [Oliver Lodge Lab., Liverpool Univ. (United Kingdom); Parry, C.M. [Dept. of Physics, York Univ., Heslington, York (United Kingdom)

    2001-03-01

    High-spin states in the {sup 96}Tc nucleus have been studied with the reactions {sup 82}Se({sup 19}F,5n{gamma}) at 68 MeV and Zn({sup 36}S,{alpha}pxn) at 130 MeV. Two {gamma}-ray cascades (irregular bandlike structures) have been observed up to an excitation energy of about 10 MeV and spin 21-22{Dirac_h}. (orig.)

  16. Altered mechanical properties of the nucleus in disease.

    Science.gov (United States)

    Lombardi, Maria Lucia; Lammerding, Jan

    2010-01-01

    In eukaryotic cells, the nucleus is the largest and most rigid organelle. Therefore, its physical properties contribute critically to the biomechanical behavior of cells, e.g., during amoeboid migration or perfusion through narrow capillaries. Furthermore, it has been speculated that nuclear deformations could directly allow cells to sense mechanical stress, e.g., by modulating the access of specific transcription factors to their binding sites. Defects in nuclear mechanics have also been reported in a variety of muscular dystrophies caused by mutations in nuclear envelope proteins, indicating an important role in the maintenance of cells in mechanically stressed tissue. These findings have prompted the growing field of nuclear mechanics to develop advanced experimental methods to study the physical properties of the nucleus as a function of nuclear structure and organization, and to understand its role in physiology and disease. These experimental techniques include micropipette aspiration, atomic force microscopy of isolated nuclei, cellular strain and compression experiments, and microneedle manipulation of intact cells. These experiments have provided important insights into the mechanical behavior of the nucleus under physiological conditions, the distinct mechanical contributions of the nuclear lamina and interior, and how mutations in nuclear envelope proteins associated with a variety of human diseases can cause distinct alterations in the physical properties of the nucleus and contribute to the disease mechanism. Here, we provide a brief overview of the most common experimental techniques and their application and discuss the implication of their results on our current understanding of nuclear mechanics. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  17. K--Nucleus Potentials Consistent with Kaonic Atoms

    Science.gov (United States)

    Cieply, A.; Friedman, E.; Gal, A.; Mares, J.

    2004-03-01

    Various models of the K- nucleus potential have been compared and tested in fits to kaonic atom data. The calculations give basically two vastly different predictions for the depth of the K- optical potential at the nuclear density. The study of the (K-stop, π ) reaction could help to distinguish between K- optical potentials as the Λ -hypernuclear formation rates are sensitive to the details of the initial-state K- wave function.

  18. Hidden Glashow resonance in neutrino–nucleus collisions

    Directory of Open Access Journals (Sweden)

    I. Alikhanov

    2016-05-01

    Full Text Available Today it is widely believed that s-channel excitation of an on-shell W boson, commonly known as the Glashow resonance, can be initiated in matter only by the electron antineutrino in the process ν¯ee−→W− at the laboratory energy around 6.3 PeV. In this Letter we argue that the Glashow resonance within the Standard Model also occurs in neutrino–nucleus collisions. The main conclusions are as follows. 1 The Glashow resonance can be excited by both neutrinos and antineutrinos of all the three flavors scattering in the Coulomb field of a nucleus. 2 The Glashow resonance in a neutrino–nucleus reaction does not manifest itself as a Breit–Wigner-like peak in the cross section but the latter exhibits instead a slow logarithmic-law growth with the neutrino energy. The resonance turns thus out to be hidden. 3 More than 98% of W bosons produced in the sub-PeV region in neutrino-initiated reactions in water/ice will be from the Glashow resonance. 4 The vast majority of the Glashow resonance events in a neutrino detector are expected at energies from a few TeV to a few tens of TeV, being mostly initiated by the conventional atmospheric neutrinos dominant in this energy range. Calculations of the cross sections for Glashow resonance excitation on the oxygen nucleus as well as on the proton are carried out in detail. The results of this Letter can be useful for studies of neutrino interactions at large volume water/ice neutrino detectors. For example, in the IceCube detector one can expect 0.3 Glashow resonance events with shower-like topologies and the deposited energies above 300 TeV per year. It is therefore likely already to have at least one Glashow resonance event in the IceCube data set.

  19. Neutrino-Nucleus Cross Sections for Oscillation Experiments

    CERN Document Server

    Katori, Teppei

    2016-01-01

    Neutrino oscillations physics is entered in the precision era. In this context accelerator-based neutrino experiments need a reduction of systematic errors to the level of a few percent. Today one of the most important sources of systematic errors are neutrino-nucleus cross sections which in the hundreds-MeV to few-GeV energy region are known with a precision not exceeding 20%. In this article we review the present experimental and theoretical knowledge of the neutrino-nucleus interaction physics. After introducing neutrino oscillation physics and accelerator-based neutrino experiments, we overview general aspects of the neutrino-nucleus cross sections, both theoretical and experimental views. Then we focus on these quantities in different reaction channels. We start with the quasielastic and quasielastic-like cross section, putting a special emphasis on multinucleon emission channel which attracted a lot of attention in the last few years. We review the main aspects of the different microscopic models for th...

  20. Integration of sensory quanta in cuneate nucleus neurons in vivo.

    Directory of Open Access Journals (Sweden)

    Fredrik Bengtsson

    Full Text Available Discriminative touch relies on afferent information carried to the central nervous system by action potentials (spikes in ensembles of primary afferents bundled in peripheral nerves. These sensory quanta are first processed by the cuneate nucleus before the afferent information is transmitted to brain networks serving specific perceptual and sensorimotor functions. Here we report data on the integration of primary afferent synaptic inputs obtained with in vivo whole cell patch clamp recordings from the neurons of this nucleus. We find that the synaptic integration in individual cuneate neurons is dominated by 4-8 primary afferent inputs with large synaptic weights. In a simulation we show that the arrangement with a low number of primary afferent inputs can maximize transfer over the cuneate nucleus of information encoded in the spatiotemporal patterns of spikes generated when a human fingertip contact objects. Hence, the observed distributions of synaptic weights support high fidelity transfer of signals from ensembles of tactile afferents. Various anatomical estimates suggest that a cuneate neuron may receive hundreds of primary afferents rather than 4-8. Therefore, we discuss the possibility that adaptation of synaptic weight distribution, possibly involving silent synapses, may function to maximize information transfer in somatosensory pathways.

  1. Maturation of firing pattern in chick vestibular nucleus neurons.

    Science.gov (United States)

    Shao, M; Hirsch, J C; Peusner, K D

    2006-08-25

    The principal cells of the chick tangential nucleus are vestibular nucleus neurons participating in the vestibuloocular and vestibulocollic reflexes. In birds and mammals, spontaneous and stimulus-evoked firing of action potentials is essential for vestibular nucleus neurons to generate mature vestibular reflex activity. The emergence of spike-firing pattern and the underlying ion channels were studied in morphologically-identified principal cells using whole-cell patch-clamp recordings from brain slices of late-term embryos (embryonic day 16) and hatchling chickens (hatching day 1 and hatching day 5). Spontaneous spike activity emerged around the perinatal period, since at embryonic day 16 none of the principal cells generated spontaneous action potentials. However, at hatching day 1, 50% of the cells fired spontaneously (range, 3 to 32 spikes/s), which depended on synaptic transmission in most cells. By hatching day 5, 80% of the principal cells could fire action potentials spontaneously (range, 5 to 80 spikes/s), and this activity was independent of synaptic transmission and showed faster kinetics than at hatching day 1. Repetitive firing in response to depolarizing pulses appeared in the principal cells starting around embryonic day 16, when calcium-dependent potassium current modulated both the spontaneous and evoked spike firing activity. Altogether, these in vitro studies showed that during the perinatal period, the principal cells switched from displaying no spontaneous spike activity at resting membrane potential and generating one spike on depolarization to the tonic firing of spontaneous and evoked action potentials.

  2. Clinical outcomes of sleeveless phacotip assisted levitation of dropped nucleus.

    Science.gov (United States)

    Agarwal, Amar; Narang, Priya; A Kumar, Dhivya; Agarwal, Ashvin

    2014-10-01

    To demonstrate the feasibility of a sleeveless phacotip-assisted approach to levitate dropped nucleus. This single-centre, retrospective, interventional, non-comparative case series reviewed the medical records of 34 eyes of 34 patients. Corrected and uncorrected distance visual acuity (CDVA, UDVA), early and late postoperative complications and ultrasound biomicroscopic (UBM) evaluation of the sclerotomy site was analysed. At 18 months follow-up, the mean postoperative UDVA and CDVA in Snellen's decimal equivalent was 0.42 ± 0.16 and 0.91 ± 0.2, respectively. There was a significant improvement in the UDVA (p=0.001) and CDVA (p=0.002). Nucleus drop occurred following intraoperative posterior capsular rupture in 25 eyes (73.5%), zonular weakness in 5 eyes (14.8%) and post-trauma in 4 eyes (11.7%). In the early postoperative period, corneal oedema was seen in 2 eyes, pigment dispersion in 3 eyes and vitritis in 2 eyes. There was loss of CDVA in 1 (2.9%) eye due to persistent cystoid macular oedema. UBM did not reveal any vitreous incarceration into the sclerotomy site. Dropped nucleus was successfully levitated into anterior chamber with this technique, resulting in a significant visual outcome with a favourable complication rate. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  3. Coexistence of central nucleus, cores, and rods: Diagnostic relevance

    Science.gov (United States)

    Dhinakaran, Sathiyabama; Kumar, Rashmi Santhosh; Thakkar, Ravindra; Narayanappa, Gayathri

    2016-01-01

    Background: Congenital myopathies (CMs) though considered distinct disorders, simultaneous occurrence of central nucleus, nemaline rods, and cores in the same biopsy are scarcely reported. Objective: A retrospective reassessment of cases diagnosed as CMs to look for multiple pathologies missed, if any, during the initial diagnosis. Materials and Methods: Enzyme histochemical, and immunohistochemical-stained slides from 125 cases diagnosed as congenital myopathy were reassessed. Results: The study revealed 15 cases (12%) of congenital myopathy with more than one morphological feature. Central nucleus with cores (n = 11), central nucleus, nemaline rods and cores (n = 3), and nemaline rods with cores (n = 1). 4/11 cases were diagnosed as centronuclear myopathy (CNM) in the first instance; in addition, cores were revealed on reassessment. Discussion: The prevalence of CMs of all neuromuscular disorders is approximately 6 in 100,000 live births, with regional variations. Three main defined CMs include centro nuclear myopathy (CNM), nemaline rod myopathy (NRM), and central core disease (CCD). However, they are more diverse with overlapping clinical and histopathological features, thus broadening the spectra within each category of congenital myopathy. Conclusion: Identification of cases with overlap of pathological features has diagnostic relevance. PMID:27293330

  4. An off-centered active galactic nucleus in NGC 3115

    CERN Document Server

    Menezes, R B; Ricci, T V

    2014-01-01

    NGC 3115 is an S0 galaxy that has always been considered to have a pure absorption-line spectrum. Some recent studies have detected a compact radio-emitting nucleus in this object, coinciding with the photometric center and with a candidate for the X-ray nucleus. This is evidence of the existence of a low-luminosity active galactic nucleus (AGN) in the galaxy, although no emission line has ever been observed. We report the detection of an emission-line spectrum of a type 1 AGN in NGC 3115, with an H$\\alpha$ luminosity of $L_{H\\alpha} = (4.2 \\pm 0.4) \\times 10^{37}$ erg s$^{-1}$. Our analysis revealed that this AGN is located at a projected distance of $\\sim 0.29" \\pm 0.05"$ (corresponding to $\\sim 14.3 \\pm 2.5$ pc) from the stellar bulge center, which is coincident with the kinematic center of this object's stellar velocity map. The black hole corresponding to the observed off-centered AGN may form a binary system with a black hole located at the stellar bulge center. However, it is also possible that the dis...

  5. Nucleus- and cell-specific gene expression in monkey thalamus.

    Science.gov (United States)

    Murray, Karl D; Choudary, Prabhakara V; Jones, Edward G

    2007-02-06

    Nuclei of the mammalian thalamus are aggregations of neurons with unique architectures and input-output connections, yet the molecular determinants of their organizational specificity remain unknown. By comparing expression profiles of thalamus and cerebral cortex in adult rhesus monkeys, we identified transcripts that are unique to dorsal thalamus or to individual nuclei within it. Real-time quantitative PCR and in situ hybridization analyses confirmed the findings. Expression profiling of individual nuclei microdissected from the dorsal thalamus revealed additional subsets of nucleus-specific genes. Functional annotation using Gene Ontology (GO) vocabulary and Ingenuity Pathways Analysis revealed overrepresentation of GO categories related to development, morphogenesis, cell-cell interactions, and extracellular matrix within the thalamus- and nucleus-specific genes, many involved in the Wnt signaling pathway. Examples included the transcription factor TCF7L2, localized exclusively to excitatory neurons; a calmodulin-binding protein PCP4; the bone extracellular matrix molecules SPP1 and SPARC; and other genes involved in axon outgrowth and cell matrix interactions. Other nucleus-specific genes such as CBLN1 are involved in synaptogenesis. The genes identified likely underlie nuclear specification, cell phenotype, and connectivity during development and their maintenance in the adult thalamus.

  6. Study of the structure of borromean nucleus 17Ne

    Institute of Scientific and Technical Information of China (English)

    LU Fei; HUA Hui; YE Yan-Lin; LI Zhi-Huan; JIANG Dong-Xing; MA Li-Ying; GE Yu-Cheng; ZHENG Tao; SONG Yu-Shou; LI Xiang-Qing; Qureshi Faisal-Jamil

    2009-01-01

    The 17Ne nucleus is a possible candidate with a two-proton borromean halo structure. Since the theoretical model is difficult to handle the three-body system, it is difficult to determine the two-proton halo structure in 17Ne. In the present research, we try to study the breakup reaction of 17Ne. For the Borromean nuclei, one-proton knockout results in an unstable nucleus which is decaying further by proton emission. This process will result in an angular correlation between the direction of the aligned recoiling unstable nucleus and its decay products. The angular correlations can give us information about the configuration of the valence proton in the 17Ne. Furthermore, theoretical calculations indicate that the momentum distributions of 16F c.m are sensitive to the structure of the halo in 17Ne. Thus the measurement of momentum distributions of 16F c.m may also give us conclusive information on the structure of 17Ne. The present experiment has been done at IMP in Lanzhou using the radioactive beam 17Ne at 30.8 MeV/u on a 43mg/cm2 12C target. The data analysis is under procedure and the primary results are provided.

  7. The size of the nucleus increases as yeast cells grow.

    Science.gov (United States)

    Jorgensen, Paul; Edgington, Nicholas P; Schneider, Brandt L; Rupes, Ivan; Tyers, Mike; Futcher, Bruce

    2007-09-01

    It is not known how the volume of the cell nucleus is set, nor how the ratio of nuclear volume to cell volume (N/C) is determined. Here, we have measured the size of the nucleus in growing cells of the budding yeast Saccharomyces cerevisiae. Analysis of mutant yeast strains spanning a range of cell sizes revealed that the ratio of average nuclear volume to average cell volume was quite consistent, with nuclear volume being approximately 7% that of cell volume. At the single cell level, nuclear and cell size were strongly correlated in growing wild-type cells, as determined by three different microscopic approaches. Even in G1-phase, nuclear volume grew, although it did not grow quite as fast as overall cell volume. DNA content did not appear to have any immediate, direct influence on nuclear size, in that nuclear size did not increase sharply during S-phase. The maintenance of nuclear size did not require continuous growth or ribosome biogenesis, as starvation and rapamycin treatment had little immediate impact on nuclear size. Blocking the nuclear export of new ribosomal subunits, among other proteins and RNAs, with leptomycin B also had no obvious effect on nuclear size. Nuclear expansion must now be factored into conceptual and mathematical models of budding yeast growth and division. These results raise questions as to the unknown force(s) that expand the nucleus as yeast cells grow.

  8. The TLC: a novel auditory nucleus of the mammalian brain.

    Science.gov (United States)

    Saldaña, Enrique; Viñuela, Antonio; Marshall, Allen F; Fitzpatrick, Douglas C; Aparicio, M-Auxiliadora

    2007-11-28

    We have identified a novel nucleus of the mammalian brain and termed it the tectal longitudinal column (TLC). Basic histologic stains, tract-tracing techniques and three-dimensional reconstructions reveal that the rat TLC is a narrow, elongated structure spanning the midbrain tectum longitudinally. This paired nucleus is located close to the midline, immediately dorsal to the periaqueductal gray matter. It occupies what has traditionally been considered the most medial region of the deep superior colliculus and the most medial region of the inferior colliculus. The TLC differs from the neighboring nuclei of the superior and inferior colliculi and the periaqueductal gray by its distinct connections and cytoarchitecture. Extracellular electrophysiological recordings show that TLC neurons respond to auditory stimuli with physiologic properties that differ from those of neurons in the inferior or superior colliculi. We have identified the TLC in rodents, lagomorphs, carnivores, nonhuman primates, and humans, which indicates that the nucleus is conserved across mammals. The discovery of the TLC reveals an unexpected level of longitudinal organization in the mammalian tectum and raises questions as to the participation of this mesencephalic region in essential, yet completely unexplored, aspects of multisensory and/or sensorimotor integration.

  9. Ground control to major TOM: mitochondria-nucleus communication.

    Science.gov (United States)

    Eisenberg-Bord, Michal; Schuldiner, Maya

    2017-01-01

    Mitochondria have crucial functions in the cell, including ATP generation, iron-sulfur cluster biogenesis, nucleotide biosynthesis, and amino acid metabolism. All of these functions require tight regulation on mitochondrial activity and homeostasis. As mitochondria biogenesis is controlled by the nucleus and almost all mitochondrial proteins are encoded by nuclear genes, a tight communication network between mitochondria and the nucleus has evolved, which includes signaling cascades, proteins which are dual-localized to the two compartments, and sensing of mitochondrial products by nuclear proteins. All of these enable a crosstalk between mitochondria and the nucleus that allows the 'ground control' to get information on mitochondria's status. Such information facilitates the creation of a cellular balance of mitochondrial status with energetic needs. This communication also allows a transcriptional response in case mitochondrial function is impaired aimed to restore mitochondrial homeostasis. As mitochondrial dysfunction is related to a growing number of genetic diseases as well as neurodegenerative conditions and aging, elucidating the mechanisms governing the mitochondrial/nuclear communication should progress a better understanding of mitochondrial dysfunctions. © 2016 Federation of European Biochemical Societies.

  10. Coexistence of central nucleus, cores, and rods: Diagnostic relevance

    Directory of Open Access Journals (Sweden)

    Sathiyabama Dhinakaran

    2016-01-01

    Full Text Available Background: Congenital myopathies (CMs though considered distinct disorders, simultaneous occurrence of central nucleus, nemaline rods, and cores in the same biopsy are scarcely reported. Objective: A retrospective reassessment of cases diagnosed as CMs to look for multiple pathologies missed, if any, during the initial diagnosis. Materials and Methods: Enzyme histochemical, and immunohistochemical-stained slides from 125 cases diagnosed as congenital myopathy were reassessed. Results: The study revealed 15 cases (12% of congenital myopathy with more than one morphological feature. Central nucleus with cores (n = 11, central nucleus, nemaline rods and cores (n = 3, and nemaline rods with cores (n = 1. 4/11 cases were diagnosed as centronuclear myopathy (CNM in the first instance; in addition, cores were revealed on reassessment. Discussion: The prevalence of CMs of all neuromuscular disorders is approximately 6 in 100,000 live births, with regional variations. Three main defined CMs include centro nuclear myopathy (CNM, nemaline rod myopathy (NRM, and central core disease (CCD. However, they are more diverse with overlapping clinical and histopathological features, thus broadening the spectra within each category of congenital myopathy. Conclusion: Identification of cases with overlap of pathological features has diagnostic relevance.

  11. Incorporation of mammalian actin into microfilaments in plant cell nucleus

    Directory of Open Access Journals (Sweden)

    Paves Heiti

    2004-04-01

    Full Text Available Abstract Background Actin is an ancient molecule that shows more than 90% amino acid homology between mammalian and plant actins. The regions of the actin molecule that are involved in F-actin assembly are largely conserved, and it is likely that mammalian actin is able to incorporate into microfilaments in plant cells but there is no experimental evidence until now. Results Visualization of microfilaments in onion bulb scale epidermis cells by different techniques revealed that rhodamine-phalloidin stained F-actin besides cytoplasm also in the nuclei whereas GFP-mouse talin hybrid protein did not enter the nuclei. Microinjection of fluorescently labeled actin was applied to study the presence of nuclear microfilaments in plant cells. Ratio imaging of injected fluorescent rabbit skeletal muscle actin and phalloidin staining of the microinjected cells showed that mammalian actin was able to incorporate into plant F-actin. The incorporation occurred preferentially in the nucleus and in the perinuclear region of plant cells whereas part of plant microfilaments, mostly in the periphery of cytoplasm, did not incorporate mammalian actin. Conclusions Microinjected mammalian actin is able to enter plant cell's nucleus, whereas incorporation of mammalian actin into plant F-actin occurs preferentially in the nucleus and perinuclear area.

  12. Pictures of Particle Production in Proton-Nucleus Collisions

    CERN Document Server

    Mueller, Alfred H

    2016-01-01

    This work focuses on gluon(jet) production in dilute(proton)-dense(nucleus) collisions. Depending on the frame and gauge, gluon production can be viewed as a freeing of gluons coming from either the proton wave function or from the nucleus wave function. These (apparently) very different pictures must lead to the same result and the purpose of this paper is to see how that happens. The focus is on gluons having $k_\\perp\\sim Q_S$ or gluons in the scaling region $k_\\perp/Q_S\\gg 1$. In the McLerran-Venugopalan(MV) model with $k_\\perp\\sim Q_S$ we are able to derive gluon production in a way that (graphically) manifestly shows $k_\\perp$-factorization in terms of the number density of gluons in the nuclear wave function. We presume that this picture, and $k_\\perp$-factorization, continues to hold in the presence of small-$x$ evolution although we have not been able to explicitly verify this. Our result is in agreement with usual $k_\\perp$-factorization where the gluon number density of the nucleus does not appear i...

  13. Formation of dense partonic matter in relativistic nucleus-nucleus collisions at RHIC: Experimental evaluation by the PHENIX collaboration

    CERN Document Server

    Adcox, K; Ajitanand, N N; Akiba, Y; Alexander, J; Aphecetche, L; Arai, Y; Aronson, S H; Averbeck, R; Awes, T C; Barish, K N; Barnes, P D; Barrette, J; Bassalleck, B; Bathe, S; Baublis, V; Bazilevsky, A; Belikov, S V; Bellaiche, F G; Belyaev, S T; Bennett, M J; Berdnikov, Yu A; Botelho, S S; Brooks, M L; Brown, D S; Bruner, N L; Bucher, D; Büsching, H; Bumazhnov, V A; Bunce, G M; Burward-Hoy, J M; Butsyk, S; Carey, T A; Chand, P; Chang, J; Chang, W C; Chavez, L L; Chernichenko, S K; Chi, C Y; Chiba, J; Chiu, M; Choudhury, R K; Christ, T; Chujo, T; Chung, M S; Chung, P; Cianciolo, V; Cole, B A; D'Enterria, D G; Dávid, G; Delagrange, H; Denisov, A; Deshpande, A A; Desmond, E J; Dietzsch, O; Dinesh, B V; Drees, A; Durum, A A; Dutta, D; Ebisu, K; Efremenko, Yu V; El-Chenawi, K F; Enyo, H; Esumi, S C; Ewell, L A; Ferdousi, T; Fields, D E; Fokin, S L; Fraenkel, Zeev; Franz, A; Frawley, A D; Fung, S Y; Garpman, S; Ghosh, T K; Glenn, A; Godoi, A L; Goto, Y; Greene, S V; Grosse-Perdekamp, M; Sen-Gupta, S K; Guryn, W; Gustafsson, Hans Åke; Haggerty, J S; Hamagaki, H; Hansen, A G; Hara, H; Hartouni, E P; Hayano, R S; Hayashi, N; He, X; Hemmick, T K; Heuser, J M; Hill, J C; Ho, D S; Homma, K; Hong, B; Hoover, A; Ichihara, T; Imai, K; Ippolitov, M S; Ishihara, M; Jacak, B V; Jang, W Y; Jia, J; Johnson, B M; Johnson, S C; Joo, K S; Kametani, S; Kang, J H; Kann, M; Kapoor, S S; Kelly, S; Khachaturov, B A; Khanzadeev, A V; Kikuchi, J; Kim, D J; Kim, H J; Kim, S Y; Kim, Y G; Kinnison, W W; Kistenev, E P; Kiyomichi, A; Klein-Bösing, C; Klinksiek, S A; Kochenda, L M; Kochetkov, D; Kochetkov, V; Köhler, D; Kohama, T; Kozlov, A; Kroon, P J; Kurita, K; Kweon, M J; Kwon, Y; Kyle, G S; Lacey, R A; Lajoie, J G; Lauret, J; Lebedev, A; Lee, D M; Leitch, M J; Li, X H; Li, Z; Lim, D J; Liu, M X; Liu, X; Liu Zu Ping; Maguire, C F; Mahon, J R; Makdisi, Y I; Man'ko, V I; Mao, Y; Mark, S K; Markacs, S; Martínez, G; Marx, M D; Masaike, A; Matathias, F; Matsumoto, T; McGaughey, P L; Melnikov, E A; Merschmeyer, M; Messer, F; Messer, M; Miake, Y; Miller, T E; Milov, A M; Mioduszewski, S; Mischke, R E; Mishra, G C; Mitchell, J T; Mohanty, A K; Morrison, D P; Moss, J M; Muhlbacher, F; Muniruzzaman, M; Murata, J; Nagamiya, S; Nagasaka, Y; Nagle, J L; Nakada, Y; Nandi, B K; Newby, J; Nikkinen, L; Nilsson, P O; Nishimura, S; Nyanin, A S; Nystrand, J; O'Brien, E; Ogilvie, C A; Ohnishi, H; Ojha, I D; Ono, M; Onuchin, V A; Oskarsson, A; Österman, L; Otterlund, I; Oyama, K; Paffrath, L; Palounek, A P T; Pantuev, V S; Papavassiliou, V; Pate, S F; Peitzmann, Thomas; Petridis, A; Pinkenburg, C H; Pisani, R P; Pitukhin, P; Plasil, F; Pollack, M E; Pope, K; Purschke, M L; Ravinovich, I; Read, K F; Reygers, K; Riabov, V; Riabov, Y; Rosati, M; Rose, A A; Ryu, S S; Saitô, N; Sakaguchi, A; Sakaguchi, T; Sako, H; Sakuma, T; Samsonov, V; Sangster, T C; Santo, R; Sato, H D; Sato, S; Sawada, S; Schlei, B R; Schutz, Y; Semenov, V; Seto, R K; Shea, T K; Shein, I V; Shibata, T A; Shigaki, K; Shiina, T; Shin, Y H; Sibiryak, Yu; Silvermyr, D; Sim, K S; Simon-Gillo, J; Singh, C P; Singh, V; Sivertz, M; Soldatov, A; Soltz, R A; Sørensen, S; Stankus, P W; Starinsky, N; Steinberg, P; Stenlund, E; Ster, A; Stoll, S P; Sugioka, M; Sugitate, T; Sullivan, J P; Sumi, Y; Sun, Z; Suzuki, M; Takagui, E M; Taketani, A; Tamai, M; Tanaka, K H; Tanaka, Y; Taniguchi, E; Tannenbaum, M J; Thomas, J; Thomas, J H; Thomas, T L; Tian, W; Tojo, J; Torii, H A; Towell, R S; Tserruya, Itzhak; Tsuruoka, H; Tsvetkov, A A; Tuli, S K; Tydesjo, H; Tyurin, N; Ushiroda, T; van Hecke, H; Velissaris, C; Velkovska, J; Velkovsky, M; Vinogradov, A A; Volkov, M A; Vorobyov, A A; Vznuzdaev, E A; Wang, H; Watanabe, Y; White, S N; Witzig, C; Wohn, F K; Woody, C L; Xie, W; Yagi, K; Yokkaichi, S; Young, G R; Yushmanov, I E; Zajc, W A; Zhang, Z; Zhou, S

    2004-01-01

    Extensive experimental data from high-energy nucleus-nucleus collisions were recorded using the PHENIX detector at the Relativistic Heavy Ion Collider (RHIC). The comprehensive set of measurements from the first three years of RHIC operation includes charged particle multiplicities, transverse energy, yield ratios and spectra of identified hadrons in a wide range of transverse momenta (p_T), elliptic flow, two-particle correlations, non-statistical fluctuations, and suppression of particle production at high p_T. The results are examined with an emphasis on implications for the formation of a new state of dense matter. We find that the state of matter created at RHIC cannot be described in terms of ordinary color neutral hadrons.

  14. A transport set-up for heavy-flavour observables in nucleus-nucleus collisions at RHIC and LHC

    CERN Document Server

    Nardi, Marzia; Beraudo, A; De Pace, A; Molinari, A; Monteno, M; Prino, F; Sitta, M

    2014-01-01

    A multi-step setup for heavy-flavour studies in high-energy nucleus–nucleus collisions is presented. The initial hard production of View the MathML sourceQ$\\bar{Q}$ pairs is simulated with the POWHEG pQCD event generator, interfaced with the PYTHIA parton shower. In a nucleus–nucleus collision the propagation of the heavy quarks in the medium is described through the relativistic Langevin equation. The numerical results are compared to experimental data from the RHIC and the LHC. In particular we show the comparisons of the nuclear modification factor of D-mesons, non-prompt J/ψJ/ψ's and heavy-flavour electrons. Furthermore, first results on azimuthal correlations of heavy quark pair and open charm/beauty meson pairs are presented.

  15. Distinct effect of orphanin FQ in nucleus raphe magnus and nucleus reticularis gigantocellularis on the rat tail flick reflex.

    Science.gov (United States)

    Yang, Z; Zhang, Y; Wu, G

    2001-06-22

    The aim of the present study is to investigate the effects of orphanin FQ (OFQ) microinjected into the nucleus raphe magnus (NRM) and the nucleus reticularis gigantocellularis (NGC) on pain modulation. The tail-flick latency (TFL) was used as a behavioral index of nociceptive responsiveness. The result showed microinjection of OFQ into the NRM significantly increased the TFL, whereas microinjection of OFQ into the NGC decreased the TFL, suggesting the analgesic effect of OFQ in the NRM and the hyperalgesic effect of OFQ in the NGC. As there are three classes of putative pain modulating neurons in the rostral ventromedial medulla (RVM), the hyperalgesic or analgesic effect of OFQ in the RVM might depend upon the different class of the neurons being acted.

  16. Formation of Centauro and Strangelets in Nucleus-Nucleus Collisions at the LHC and their Identification by the ALICE Experiment

    CERN Document Server

    Angelis, Aris L S; Bogolyubsky, M Yu; Filippov, S N; Gladysz-Dziadus, E; Kharlov, Yu V; Kurepin, A B; Maevskaya, A I; Mavromanolakis, G; Panagiotou, A D; Sadovsky, S A; Stefanski, P; Wlodarczyk, Z

    1999-01-01

    Presentation made at the 26th International Cosmic Ray Conference, ICRC'99We present a phenomenological model which describes the formation of a Centauro fireball in nucleus-nucleus interactions in the upper atmosphere and at the LHC, and its decay to non-strange baryons and Strangelets. We describe the CASTOR detector for the ALICE experiment at the LHC. CASTOR will probe, in an event-by-event mode, the very forward, baryon-rich phase space 5.6eta7.2 in 5.5xA TeV central Pb+Pb collisions. We present results of simulations for the response of the CASTOR calorimeter and, in particular, to the transversal of Strangelets.

  17. CASTOR A Forward Detector for the Identification of Centauro and Strangelets in Nucleus-Nucleus Collisions at the LHC

    CERN Document Server

    Angelis, Aris L S; Bogolyubsky, M Yu; Filippov, S N; Gladysz-Dziadus, E; Kharlov, Yu V; Kurepin, A B; Maevskaya, A I; Mavromanolakis, G; Panagiotou, A D; Sadovsky, S A; Stefanski, P; Wlodarczyk, Z

    2000-01-01

    Presentation made at the XXVIIIth Symposium on Multiparticle Dynamics, 6-11 September 1998, Delphi and published in World ScientificThe physics motivation for a very forward detector to be employed in heavy ion collisions at the CERN LHC is discussed. A phenomenological model describing the formation and decay of a Centauro fireball in nucleus-nucleus collisions is presented. The CASTOR detector which is aimed to measure the hadronic and photonic content of an interaction and to identify deeply penetrating objects in the very forward, baryon-rich phase space 5.6eta7.2 in an event-by-event mode is described. Results of simulations of the expected response of the calorimeter and, in particular, to the passage of strangelets, are presented.

  18. Nucleus-encoded periplastid-targeted EFL in chlorarachniophytes.

    Science.gov (United States)

    Gile, Gillian H; Keeling, Patrick J

    2008-09-01

    Chlorarachniophytes are cercozoan amoeboflagellates that acquired photosynthesis by enslaving a green alga, which has retained a highly reduced nucleus called a nucleomorph. The nucleomorph lacks many genes necessary for its own maintenance and expression, suggesting that some genes have been moved to the host nucleus and their products are now targeted back to the periplastid compartment (PPC), the reduced eukaryotic cytoplasm of the endosymbiont. Protein trafficking in chlorarachniophytes is therefore complex, including nucleus-encoded plastid-targeted proteins, nucleomorph-encoded plastid-targeted proteins, and nucleus-encoded periplastid-targeted proteins. A major gap in our understanding of this system is the PPC-targeted proteins because none have been described in any chlorarachniophytes. Here we describe the first such protein, the GTPase EFL. EFL was characterized from 7 chlorarachniophytes, and 2 distinct types were found. One is related to foraminiferan EFL and lacks an amino-terminal extension. The second, distantly related, type encodes an amino-terminal extension consisting of a signal peptide followed by sequence sharing many characteristics with transit peptides from nucleus-encoded plastid-targeted proteins and which we conclude is most likely PPC targeted. Western blotting with antibodies specific to putative host and PPC-targeted EFL from the chlorarachniophytes Bigelowiella natans and Gymnochlora stellata is consistent with posttranslational cleavage of the leaders from PPC-targeted proteins. Immunolocalization of both proteins in B. natans confirmed the cytosolic location of the leaderless EFL and a distinct localization pattern for the PPC-targeted protein but could not rule out a plastid location (albeit very unlikely). We sought other proteins with a similar leader and identified a eukaryotic translation initiation factor 1 encoding a bipartite extension with the same properties. Transit peptide sequences were characterized from all 3

  19. Serotonergic modulation of astrocytic activity in the hamster suprachiasmatic nucleus.

    Science.gov (United States)

    Glass, J D; Chen, L

    1999-01-01

    The present study was undertaken to explore the effects of central serotonin receptor activation on the expression of glial fibrillary acidic protein in the suprachiasmatic nucleus of Syrian hamsters. Immunoblot and immunohistochemical procedures were used to examine the effects of systemic application of the serotonin-1A and serotonin-7 receptor agonist, (+/-)-2-dipropyl-amino-8-hydroxyl-1,2,3,4-tetrahydronaphthalene hydrobromide (8-OH-DPAT; 3.75 mg/kg) on the contents and distribution of glial fibrillary acidic protein in the suprachiasmatic nucleus. Administration of 8-OH-DPAT at midday caused a significant reduction in immunoreactive glial fibrillary acidic protein content within 1 h of injection, compared to vehicle controls. This effect was not evident 3 h after drug injection. Treatment with 8-OH-DPAT during the late dark phase had little effect on glial fibrillary acidic protein content. The 8-OH-DPAT-induced reduction in glial fibrillary acidic protein content seen at midday was blocked partially by pretreatment with the serotonin-2 and serotonin-7 receptor antagonist, ritanserin, and more substantially by pretreatment with the serotonin-1A receptor antagonist, NAN-190. Treatment with 8-OH-DPAT also caused a significant redistribution of immunoreactive glial fibrillary acidic protein, such that the dense mesh-like appearance seen in vehicle controls was significantly reduced. The 8-OH-DPAT treatment also significantly decreased expression of polysialic acid, a cell-surface molecule associated with neural plasticity. Immunoblot assessments of glial fibrillary acidic protein contents 2 h before and 1 h after lights off revealed a significant time-of-day difference in glial fibrillary acidic protein expression, with lowest levels occurring at the latter time-point, associated with maximal endogenous serotonin release in the suprachiasmatic nucleus. Collectively, these results indicate that acute plastic changes in glial fibrillary acidic protein

  20. Study of the peculiarities of multiparticle production via event-by-event analysis in asymmetric nucleus-nucleus interactions

    Science.gov (United States)

    Fedosimova, Anastasiya; Gaitinov, Adigam; Grushevskaya, Ekaterina; Lebedev, Igor

    2017-06-01

    In this work the study on the peculiarities of multiparticle production in interactions of asymmetric nuclei to search for unusual features of such interactions, is performed. A research of long-range and short-range multiparticle correlations in the pseudorapidity distribution of secondary particles on the basis of analysis of individual interactions of nuclei of 197 Au at energy 10.7 AGeV with photoemulsion nuclei, is carried out. Events with long-range multiparticle correlations (LC), short-range multiparticle correlations (SC) and mixed type (MT) in pseudorapidity distribution of secondary particles, are selected by the Hurst method in accordance with Hurst curve behavior. These types have significantly different characteristics. At first, they have different fragmentation parameters. Events of LC type are processes of full destruction of the projectile nucleus, in which multicharge fragments are absent. In events of mixed type several multicharge fragments of projectile nucleus are discovered. Secondly, these two types have significantly different multiplicity distribution. The mean multiplicity of LC type events is significantly more than in mixed type events. On the basis of research of the dependence of multiplicity versus target-nuclei fragments number for events of various types it is revealed, that the most considerable multiparticle correlations are observed in interactions of the mixed type, which correspond to the central collisions of gold nuclei and nuclei of CNO-group, i.e. nuclei with strongly asymmetric volume, nuclear mass, charge, etc. Such events are characterised by full destruction of the target-nucleus and the disintegration of the projectile-nucleus on several multi-charged fragments.

  1. Superscaling in electron-nucleus scattering and its link to CC and NC QE neutrino-nucleus scattering

    CERN Document Server

    Barbaro, M B; Caballero, J A; Donnelly, T W; Gonzalez-Jimenez, R; Ivanov, M; Udias, J M

    2013-01-01

    The superscaling approach (SuSA) to neutrino-nucleus scattering, based on the assumed universality of the scaling function for electromagnetic and weak interactions, is reviewed. The predictions of the SuSA model for bot CC and NC differential and total cross sections are presented and compared with the MiniBooNE data. The role of scaling violations, in particular the contribution of meson exchange currents in the two-particle two-hole sector, is explored.

  2. Superscaling in electron-nucleus scattering and its link to CC and NC QE neutrino-nucleus scattering

    Energy Technology Data Exchange (ETDEWEB)

    Barbaro, M. B. [Università di Torino and INFN, Sezione di Torino, 10125 Torino (Italy); Amaro, J. E. [Universidad de Granada, 18071 Granada (Spain); Caballero, J. A.; González-Jiménez, R. [Universidad de Sevilla, 41080 Sevilla (Spain); Donnelly, T. W. [CTP, LNS and Department of Physics, MIT, Cambridge, MA 02139 (United States); Ivanov, M. [Institute for Nuclear Research and Nuclear Energy, Sofia 1784 (Bulgaria); Udías, J. M. [Universidad Complutense de Madrid, 28040 Madrid (Spain)

    2015-05-15

    The superscaling approach (SuSA) to neutrino-nucleus scattering, based on the assumed universality of the scaling function for electromagnetic and weak interactions, is reviewed. The predictions of the SuSA model for bot CC and NC differential and total cross sections are presented and compared with the MiniBooNE data. The role of scaling violations, in particular the contribution of meson exchange currents in the two-particle two-hole sector, is explored.

  3. Volumetric alterations in the nucleus accumbens and caudate nucleus in bulimia nervosa: a structural magnetic resonance imaging study.

    Science.gov (United States)

    Coutinho, Joana; Ramos, Ana Filipa; Maia, Liliana; Castro, Liliana; Conceição, Eva; Geliebter, Allan; Machado, Paulo P P; Gonçalves, Óscar; Sampaio, Adriana

    2015-03-01

    Bulimia nervosa (BN) is an eating disorder characterized by recurrent episodes of binge eating and inappropriate compensatory behaviors (such as purging, fasting, or excessive exercise) to prevent weight gain. BN has been associated with deficits in inhibitory control processes. The basal ganglia specifically, the nucleus accumbens (NAc) and the caudate nucleus (CN) are part of the frontostriatal circuits involved in inhibitory control. The main goal of this study was to investigate the presence of morphological alterations in the NAc and the CN in a sample of patients diagnosed with BN. Forty-one female participants, 21 diagnosed with BN and 20 healthy matched controls (HC), underwent a structural magnetic resonance imaging (MRI) acquisition and clinical assessment. The NAc and the CN were manually segmented using the software Slicer 3D. The results reveal a significant volumetric decrease in the CN and a preserved NAc volume in BN compared to the control group. These findings suggest a contributory role of the caudate nucleus part of the dorsal striatum in the psychopathology of BN. © 2014 Wiley Periodicals, Inc.

  4. The Double Nucleus and Central Black Hole of M31

    Science.gov (United States)

    Kormendy, John; Bender, Ralf

    1999-09-01

    New spectroscopy of M31 supports Tremaine's model in which both nuclei are parts of a single eccentric disk of stars orbiting the black hole (BH). The kinematics and Hubble Space Telescope photometry are used to measure the offset of the BH from the center of mass. This confirms that the BH mass is ~3×107 Msolar by a technique that is nearly independent of stellar-dynamical models. We present spectroscopy of the nucleus of M31 obtained with the Canada-France-Hawaii Telescope and Subarcsecond Imaging Spectrograph. Spectra at the Ca infrared triplet lines (seeing σ*=0.27") are used to measure the stellar kinematics, and spectra at the Mg I b lines (σ*=0.31") are used to measure metallicities. We also measure nonparametric line-of-sight velocity distributions (LOSVDs). All spectra confirm the steep rotation and velocity dispersion gradients that imply that M31 contains a 3.3×107 Msolar central dark object. At σ*=0.27", the maximum bulge-subtracted rotation velocity of the nucleus is 233+/-4 km s-1 on the P2 side, and the maximum velocity dispersion is 287+/-9 km s-1. The dispersion peak is displaced by 0.20"+/-0.03" from the velocity center in the direction opposite to P1, confirming a result by Bacon and coworkers. The higher surface brightness nucleus, P1, is colder than the bulge, with σ~=100 km s-1 at r~=1''. Cold light from P1 contributes at the velocity center; this explains part of the σ(r) asymmetry. The nucleus is cold at r>~1'' on both sides of the center. Our results are used to test Tremaine's model in which the double nucleus is a single eccentric disk of stars orbiting the BH. (1) The model predicts that the velocity center of the nucleus is displaced by 0.2" from P2 toward P1. Our observations show a displacement of 0.08"+/-0.01" before bulge subtraction and 0.10"+/-0.01" after bulge subtraction. (2) The model predicts a minimum σ~=135 km s-1 at P1. We observe σ=123+/-2 km s-1. Observations (1) and (2) may be reconciled with the model if its

  5. Stereotactic localization and visualization of the subthalamic nucleus

    Institute of Scientific and Technical Information of China (English)

    SHEN Wei-gao; WANG Hai-yang; LIN Zhi-guo; SHEN Hong; CHEN Xiao-guang; FU Yi-li; GAO Wen-peng

    2009-01-01

    Background The subthalamic nucleus (STN) is widely recognized as one of the most important and commonly targeted nuclei in stereotactic and functional neurosurgery. The success of STN surgery depends on accuracy in target determination. Construction of a digitalized atlas of STN based on stereotactic MRI will play an instrumental role in the accuracy of anatomical localization. The aim of this study was to investigate the three-dimensional (3D) target location of STN in stereotactic space and construct a digitalized atlas of STN to accomplish the visualization of the STN on stereotactic MRI, thus providing clinical guidance on the precise anatomical localization of STN.Methods One hundred and twenty healthy people volunteered to be scanned by 1.5 Tesla MRI scanning with 1-mm-thick slice in the standard stereotactic space between 2005 and 2006. One adult male was selected for 3D reconstruction of STN. The precess of 3D reconstruction included identification, manual segmentation, extraction,conservation and reconstruction.Results There was a significant correlation between the coordinates and age (P <0.05). The volume of left STN was significantly larger than the right STN, and there was a significant negative correlation between volume and age (P <0.05).The surface of the STN nucleus after 3D reconstruction appeared smooth, natural and realistic. The morphological feature of STN on the individual brain could be visualized directly in 3D. The 3D reconstructed STN could be rotated,zoomed and displayed at any direction in the stereotactic space. The anteroposterior diameter of the STN nucleus was longer than the vertical and transverse diameters in 3D space. The 3D reconstruction of STN manifested typical structure of the "dual lens".Conclusions The visualization of individual brain atlas based on stereotactic MRI is feasible. However, software for automated segmentation, extraction and registration of MR images need to be further developed.

  6. Tractography patterns of subthalamic nucleus deep brain stimulation.

    Science.gov (United States)

    Vanegas-Arroyave, Nora; Lauro, Peter M; Huang, Ling; Hallett, Mark; Horovitz, Silvina G; Zaghloul, Kareem A; Lungu, Codrin

    2016-04-01

    Deep brain stimulation therapy is an effective symptomatic treatment for Parkinson's disease, yet the precise mechanisms responsible for its therapeutic effects remain unclear. Although the targets of deep brain stimulation are grey matter structures, axonal modulation is known to play an important role in deep brain stimulation's therapeutic mechanism. Several white matter structures in proximity to the subthalamic nucleus have been implicated in the clinical benefits of deep brain stimulation for Parkinson's disease. We assessed the connectivity patterns that characterize clinically beneficial electrodes in Parkinson's disease patients, after deep brain stimulation of the subthalamic nucleus. We evaluated 22 patients with Parkinson's disease (11 females, age 57 ± 9.1 years, disease duration 13.3 ± 6.3 years) who received bilateral deep brain stimulation of the subthalamic nucleus at the National Institutes of Health. During an initial electrode screening session, one month after deep brain stimulation implantation, the clinical benefits of each contact were determined. The electrode was localized by coregistering preoperative magnetic resonance imaging and postoperative computer tomography images and the volume of tissue activated was estimated from stimulation voltage and impedance. Brain connectivity for the volume of tissue activated of deep brain stimulation contacts was assessed using probabilistic tractography with diffusion-tensor data. Areas most frequently connected to clinically effective contacts included the thalamus, substantia nigra, brainstem and superior frontal gyrus. A series of discriminant analyses demonstrated that the strength of connectivity to the superior frontal gyrus and the thalamus were positively associated with clinical effectiveness. The connectivity patterns observed in our study suggest that the modulation of white matter tracts directed to the superior frontal gyrus and the thalamus is associated with favourable clinical

  7. Natural orbital description of the halo nucleus 6He

    CERN Document Server

    Constantinou, Ch; Vary, J P; Maris, P

    2016-01-01

    Ab initio calculations of nuclei face the challenge of simultaneously describing strong short-range internucleon correlations and the long-range properties of weakly-bound halo nucleons. Natural orbitals, which diagonalize the one-body density matrix, provide a basis which is better matched to the physical structure of the many-body wave function. We demonstrate that the use of natural orbitals significantly improves convergence for ab initio no-core configuration interaction calculations of the neutron halo nucleus 6He, relative to the traditional oscillator basis.

  8. Modelling of compound nucleus formation in fusion of heavy nuclei

    CERN Document Server

    Díaz-Torres, A

    2004-01-01

    A new model that includes the time-dependent dynamics of the single-particle (s.p.) motion in conjunction with the macroscopic evolution of the system is proposed for describing the compound nucleus (CN) formation in fusion of heavy nuclei. The diabaticity initially keeps the entrance system around its contact configuration, but the gradual transition from the diabatic to the adiabatic potential energy surface (PES) leads to fusion or quasifission. Direct measurements of the probability for CN formation are crucial to discriminate between the current models.

  9. Neutrino-nucleus interactions and the determination of oscillation parameters

    CERN Document Server

    Benhar, Omar; Mariani, Camillo; Meloni, Davide

    2015-01-01

    We review the status and prospects of theoretical studies of neutrino-nucleus interactions, and discuss the influence of the treatment of nuclear effects on the determination of oscillation parameters. The models developed to describe the variety of reaction mechanisms contributing to the nuclear cross sections are analysed, with emphasis placed on their capability to reproduce the available electron scattering data.The impact of the uncertainties associated with the description of nuclear dynamics on the the oscillation parameters is illustrated through examples, and possible avenues towards a better understanding of the signals detected by long baseline experiments are outlined.

  10. Dopamine system, cerebellum, and nucleus ruber in fish and mammals.

    Science.gov (United States)

    Matsui, Hideaki

    2017-05-01

    Small teleost fish including zebrafish and medaka have been used as animal models for research because of their small body size, vast amounts of eggs produced, their rapid development, low husbandry costs, and transparency during embryogenesis. Although the body size and appearance seem different, fish and mammals including human still possess anatomical and functional similarities in their brains. This review summarizes the similarities of brain structures and functions between teleost fish and mammalian brains, focusing on the dopamine system, functional regionalization of the cerebellum, and presence of the nucleus ruber. © 2017 Japanese Society of Developmental Biologists.

  11. Spatial regulation and organization of DNA replication within the nucleus.

    Science.gov (United States)

    Natsume, Toyoaki; Tanaka, Tomoyuki U

    2010-01-01

    Duplication of chromosomal DNA is a temporally and spatially regulated process. The timing of DNA replication initiation at various origins is highly coordinated; some origins fire early and others late during S phase. Moreover, inside the nuclei, the bulk of DNA replication is physically organized in replication factories, consisting of DNA polymerases and other replication proteins. In this review article, we discuss how DNA replication is organized and regulated spatially within the nucleus and how this spatial organization is linked to temporal regulation. We focus on DNA replication in budding yeast and fission yeast and, where applicable, compare yeast DNA replication with that in bacteria and metazoans.

  12. On the symmetries of the 12C nucleus

    CERN Document Server

    Cseh, J

    2016-01-01

    The consequences of some symmetries of the three-alpha system are discussed. In particular, the recent description of the low-energy spectrum of the 12C nucleus in terms of the Algebraic Cluster Model (ACM) is compared to that of the Semimicroscopic Algebraic Cluster Model (SACM). The previous one applies interactions of a D3h geometric symmetry [1], while the latter one has a U(3) multichannel dynamical symmetry, that connects the shell and cluster pictures. The available data is in line with both descriptions.

  13. [Mutations in the personality nucleus at puberty and adolescence].

    Science.gov (United States)

    Schiopu, U

    1989-01-01

    The author considers that analysing the personality by means of concrete research, the axis "self-perceptual Ego and the prospective, ideal Ego" make up an operational axis included in personality nucleus. The selected interference of the alter image about the Ego permanently readjusts this axis. In this purpose an adjective checklist and the projective test TST in two alternative have been used. The author concludes that during puberty and adolescence several changes take place as far as the number of adjective used, descriptors prevailing characteristics, and affective finality are concerned.

  14. Spin Symmetry for Anti-Lambda Spectrum in atomic nucleus

    CERN Document Server

    Song, Chunyan; Meng, Jie

    2009-01-01

    The spin symmetry of anti-Lambda spectrum in nucleus ^{16}O has been studied in the relativistic mean field theory. The spin-orbit splittings of spin doublets are found to be around 0.03-0.07 MeV and the dominant components of the Dirac spinor for the anti-Lambda spin doublets are found to be near identical. It indicates that there is an even better spin symmetry in the anti-Lambda spectrum than that in the anti-nucleon spectrum.

  15. Active galactic nucleus feedback in clusters of galaxies

    CERN Document Server

    Blanton, Elizabeth L; Sarazin, Craig L; Randall, Scott W; McNamara, Brian R; ),

    2010-01-01

    Observations made during the last ten years with the Chandra X-ray Observatory have shed much light on the cooling gas in the centers of clusters of galaxies and the role of active galactic nucleus (AGN) heating. Cooling of the hot intracluster medium in cluster centers can feed the supermassive black holes found in the nuclei of the dominant cluster galaxies leading to AGN outbursts which can reheat the gas, suppressing cooling and large amounts of star formation. AGN heating can come in the form of shocks, buoyantly rising bubbles that have been inflated by radio lobes, and the dissipation of sound waves.

  16. New method of estimation of cosmic ray nucleus energy

    CERN Document Server

    Korotkova, N A; Postnikov, E B; Roganova, T M; Sveshnikova, L G; Turundaevskij, A N

    2002-01-01

    The new approach to estimation of primary cosmic nucleus energy is presented. It is based on measurement of spatial density of secondary particles, originated in nuclear interactions in the target and strengthened by thin converter layer. The proposed method allows creation of relatively lightweight apparatus of large square with large geometrical factor and can be applied in satellite and balloon experiments for all nuclei in a wide energy range of 10 sup 1 sup 1 -10 sup 1 sup 6 eV/particle. The physical basis of the method, full Monte Carlo simulation, the field of application are presented

  17. Research Program towards Observation of Neutrino-Nucleus Coherent Scattering

    CERN Document Server

    Wong, H T

    2006-01-01

    The article describes the research program pursued by the TEXONO Collaboration towards an experiment to observe coherent scattering between neutrinos and the nucleus at the power reactor. The motivations of studying this process are surveyed. In particular, a threshold of 100-200 eV has been achieved with an ultra-low-energy germanium detector prototype. This detection capability at low energy can also be adapted to conduct searches of Cold Dark Matter in the low-mass region as well as to enhance the sensitivities in the study of neutrino magnetic moments.

  18. Spin Symmetry for Anti-Lambda Spectrum in Atomic Nucleus

    Institute of Scientific and Technical Information of China (English)

    SONG Chun-Yan; YAO Jiang-Ming; MENG Jie

    2009-01-01

    The spin symmetry of the anti-Lambda spectrum in nucleus ~(16)O is studied in the relativistic mean field theory.The spin-orbit splittings of spin doublets are found to be around 0.03-0.07 MeV and the dominant components of the Dirac spinor for the anti-Lambda spin doublets are found to be near identical.It is indicated that there is an even better spin symmetry in the anti-Lambda spectrum than that in the anti-nucleon spectrum.

  19. Hypersexuality following subthalamic nucleus stimulation for Parkinson's disease.

    Science.gov (United States)

    Doshi, Paresh; Bhargava, Pranshu

    2008-01-01

    Subthalamic nucleus (STN) stimulation is an established surgical treatment for Parkinson's disease (PD). Though the motor benefits of STN stimulation are well understood, its cognitive and behavioral effects are still not fully understood. Manic psychosis, hypersexuality, pathological gambling and mood swings are associated with advanced PD. There have been reports to suggest improvement or worsening in these symptoms following STN deep brain stimulation (DBS). We report two cases as the sole behavioral side-effects of STN stimulation despite good clinical improvement on long-term follow-up. These patients and literature review suggests the complex role of STN stimulation in motor and behavioral control.

  20. Hypersexuality following subthalamic nucleus stimulation for Parkinson′s disease

    Directory of Open Access Journals (Sweden)

    Doshi Paresh

    2008-01-01

    Full Text Available Subthalamic nucleus (STN stimulation is an established surgical treatment for Parkinson′s disease (PD. Though the motor benefits of STN stimulation are well understood, its cognitive and behavioral effects are still not fully understood. Manic psychosis, hypersexuality, pathological gambling and mood swings are associated with advanced PD. There have been reports to suggest improvement or worsening in these symptoms following STN deep brain stimulation (DBS. We report two cases as the sole behavioral side-effects of STN stimulation despite good clinical improvement on long-term follow-up. These patients and literature review suggests the complex role of STN stimulation in motor and behavioral control.

  1. Isospin symmetry violation, meson production and -nucleus interaction studies

    Indian Academy of Sciences (India)

    B J Roy; V Jha; A Chatterje; H Machner; GEM Collaboration

    2006-05-01

    We have studied isospin symmetry violation in nuclear reactions by measuring simultaneously the cross-section of the following two reactions + → 3H + and + → 3He 0. The experiment was perfomed at the cooler synchrotron accelerator. COSY, Jülich at several beam energies close to the corresponding production threshold. We also have ongoing programmes on -nucleus final-state interaction studies via + 6Li → 7Be + reactions, high resolution search for dibaryonic resonances and lambda-proton final state interaction studies. The experimental details and results obtained so far are presented here.

  2. Magnetic Moment of Proton Drip-Line Nucleus (9)C

    Science.gov (United States)

    Matsuta, K.; Fukuda, M.; Tanigaki, M.; Minamisono, T.; Nojiri, Y.; Mihara, M.; Onishi, T.; Yamaguchi, T.; Harada, A.; Sasaki, M.

    1994-01-01

    The magnetic moment of the proton drip-line nucleus C-9(I(sup (pi)) = 3/2, T(sub 1/2) = 126 ms) has been measured for the first time, using the beta-NMR detection technique with polarized radioactive beams. The measure value for the magnetic moment is 1mu(C-9)! = 1.3914 +/- 0.0005 (mu)N. The deduced spin expectation value of 1.44 is unusually larger than any other ones of even-odd nuclei.

  3. Sizing and shaping the nucleus: mechanisms and significance.

    Science.gov (United States)

    Jevtić, Predrag; Edens, Lisa J; Vuković, Lidija D; Levy, Daniel L

    2014-06-01

    The size and shape of the nucleus are tightly regulated, indicating the physiological significance of proper nuclear morphology, yet the mechanisms and functions of nuclear size and shape regulation remain poorly understood. Correlations between altered nuclear morphology and certain disease states have long been observed, most notably many cancers are diagnosed and staged based on graded increases in nuclear size. Here we review recent studies investigating the mechanisms regulating nuclear size and shape, how mitotic events influence nuclear morphology, and the role of nuclear size and shape in subnuclear chromatin organization and cancer progression. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Collective Band Structures in Neutron-Rich 108Mo Nucleus

    Institute of Scientific and Technical Information of China (English)

    DING Huai-Bo; WANG Jian-Guo; XU Qiang; ZHU Sheng-Jiang; J. H. Hamilton; A. V. Ramayya; J. K. Hwang; Y. X. Luo; J. O. Rasmussen; I. Y. Lee; CHE Xing-Lai

    2007-01-01

    High spin states in the neutron-rich 108Mo nucleus are studied by measuring prompt γ-rays following the spontaneous fission of 252Cf with a Gammasphere detector array. The ground-state band is confirmed, and the one-phonon γ-vibrational band is updated with spin up to 12 h. A new collective band with the band head level at 1422.4 keV is suggested as a two-phonon γ-vibrational band. Another new band is proposed as a two-quasi-proton excitation band. Systematic characteristics of the collective bands are discussed.

  5. Electric multipole response of the halo nucleus {sup 6}He

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Jagjit; Fortunato, L.; Vitturi, A. [Dipartimento di Fisica e Astronomia ' ' G. Galilei' ' , Padova (Italy); INFN, Sezione di Padova, Padova (Italy); Chatterjee, R. [Indian Institute of Technology, Department of Physics, Roorkee (India)

    2016-07-15

    The role of different continuum components in the weakly bound nucleus {sup 6}He is studied by coupling unbound spd-waves of {sup 5}He by means of simple pairing contact-delta interaction. The results of our previous investigations in a model space containing only p-waves showed the collective nature of the ground state and allowed the calculation of the electric quadrupole transitions. We extend this simple model by including also sd-continuum neutron states and we investigate the electric monopole, dipole and octupole response of the system for transitions to the continuum, discussing the contribution of different configurations. (orig.)

  6. The exosome and RNA quality control in the nucleus

    OpenAIRE

    Vanacova, Stepanka; Stef, Richard

    2007-01-01

    To control the quality of RNA biogenesis in the nucleus, cells use sophisticated molecular machines. These machines recognize and degrade not only RNA trimmings—the leftovers of RNA processing—but also incorrectly processed RNAs that contain defects. By using this mechanism, cells ensure that only high-quality RNAs are engaged in protein synthesis and other cellular processes. The exosome—a complex of several exoribonucleolytic and RNA-binding proteins—is the central 3′-end RNA degradation an...

  7. Anisomycin infusions in the parabrachial nucleus and taste neophobia.

    Science.gov (United States)

    Lin, Jian-You; Amodeo, Leslie Renee; Arthurs, Joe; Reilly, Steve

    2012-11-01

    To investigate whether de novo protein synthesis in the parabrachial nucleus (PBN) is required for recovery from taste neophobia, anisomycin (a protein synthesis inhibitor) was infused immediately after consumption of a novel saccharin solution (Experiment 1). Unexpectedly, this PBN treatment caused a reduction in saccharin intake. In addition, we found that the anisomycin-induced suppression of tastant intake was attenuated by prior intra-PBN infusions of lidocaine (Experiment 2). This pattern of results raises concerns about using anisomycin to investigate memory consolidation processes in the PBN. Thus, a different manipulation may be needed to examine the nature of the neuroplastic changes that occur in the PBN during taste memory formation.

  8. Hyperpolarisation effects on the electric field gradient at a nucleus

    Science.gov (United States)

    Fowler, P. W.

    1989-04-01

    The electric field gradient at the nucleus of an atom or ion depends quadratically on the external electric field through the ɛ hyperpolarisability. Ab initio Hartree-Fock calculations on the He, Ne and Ar isoelectronic series show that ɛ is positive for s 2 and negative for p 6 electronic configurations, always having the opposite sign to the Sternheimer antishielding factor. The ab initio values for free atoms and ions conflict in sign with the effective hyperpolarisation term in one ionic model of nuclear quadrupole constants of gaseous alkali halides but the sign of the empirical parameter could change if overlap damping of the Sternheimer response were included in the model.

  9. Red nucleus and rubrospinal tract disorganization in the absence of Pou4f1

    Directory of Open Access Journals (Sweden)

    Jesus E. eMartinez-Lopez

    2015-02-01

    Full Text Available The red nucleus is a neuronal population that plays an important role in forelimb motor control and locomotion. Histologically it is subdivided into two subpopulations, the parvocellular red nucleus located in the diencephalon and the magnocellular red nucleus in the mesencephalon. The red nucleus integrates signals from motor cortex and cerebellum and projects to spinal cord interneurons and motor neurons through the rubrospinal tract. Pou4f1 is a transcription factor highly expressed in this nucleus that has been related to its specification. Here we profoundly analyzed consequences of Pou4f1 loss-of-function in development, maturation and axonal projection of the red nucleus. Surprisingly, red nucleus neurons are specified and maintained in the mutant, no cell death was detected. Nevertheless, the nucleus appeared disorganized with a strong delay in radial migration and with a wider neuronal distribution; the neurons did not form a compacted population as they do in controls, Robo1 and Slit2 were miss-expressed. Cplx1 and Npas1, expressed in the red nucleus, are transcription factors involved in neurotransmitter release, neuronal maturation and motor function processes among others. In our mutant mice, both transcription factors are lost, suggesting an abnormal maturation of the red nucleus. The resulting altered nucleus occupied a wider territory. Finally, we examined rubrospinal tract development and found that the red nucleus neurons were able to project to the spinal cord but their axons appeared defasciculated. These data suggest that Pou4f1 is necessary for the maturation of red nucleus neurons but not for their specification and maintenance.

  10. Nucleus-Dependent Valence-Space Approach to Nuclear Structure

    Science.gov (United States)

    Stroberg, S. R.; Calci, A.; Hergert, H.; Holt, J. D.; Bogner, S. K.; Roth, R.; Schwenk, A.

    2017-01-01

    We present a nucleus-dependent valence-space approach for calculating ground and excited states of nuclei, which generalizes the shell-model in-medium similarity renormalization group to an ensemble reference with fractionally filled orbitals. Because the ensemble is used only as a reference, and not to represent physical states, no symmetry restoration is required. This allows us to capture three-nucleon (3 N ) forces among valence nucleons with a valence-space Hamiltonian specifically targeted to each nucleus of interest. Predicted ground-state energies from carbon through nickel agree with results of other large-space ab initio methods, generally to the 1% level. In addition, we show that this new approach is required in order to obtain convergence for nuclei in the upper p and s d shells. Finally, we address the 1+/3+ inversion problem in 22Na and 46V. This approach extends the reach of ab initio nuclear structure calculations to essentially all light- and medium-mass nuclei.

  11. Finding Hierarchical and Overlapping Dense Subgraphs using Nucleus Decompositions

    Energy Technology Data Exchange (ETDEWEB)

    Seshadhri, Comandur [The Ohio State Univ., Columbus, OH (United States); Pinar, Ali [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sariyuce, Ahmet Erdem [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Catalyurek, Umit [The Ohio State Univ., Columbus, OH (United States)

    2014-11-01

    Finding dense substructures in a graph is a fundamental graph mining operation, with applications in bioinformatics, social networks, and visualization to name a few. Yet most standard formulations of this problem (like clique, quasiclique, k-densest subgraph) are NP-hard. Furthermore, the goal is rarely to nd the \\true optimum", but to identify many (if not all) dense substructures, understand their distribution in the graph, and ideally determine a hierarchical structure among them. Current dense subgraph nding algorithms usually optimize some objective, and only nd a few such subgraphs without providing any hierarchy. It is also not clear how to account for overlaps in dense substructures. We de ne the nucleus decomposition of a graph, which represents the graph as a forest of nuclei. Each nucleus is a subgraph where smaller cliques are present in many larger cliques. The forest of nuclei is a hierarchy by containment, where the edge density increases as we proceed towards leaf nuclei. Sibling nuclei can have limited intersections, which allows for discovery of overlapping dense subgraphs. With the right parameters, the nuclear decomposition generalizes the classic notions of k-cores and k-trusses. We give provable e cient algorithms for nuclear decompositions, and empirically evaluate their behavior in a variety of real graphs. The tree of nuclei consistently gives a global, hierarchical snapshot of dense substructures, and outputs dense subgraphs of higher quality than other state-of-theart solutions. Our algorithm can process graphs with tens of millions of edges in less than an hour.

  12. Lifetime measurements in shape transition nucleus {sup 188}Pt

    Energy Technology Data Exchange (ETDEWEB)

    Rohilla, Aman; Gupta, C.K.; Chamoli, S.K. [University of Delhi, Department of Physics and Astrophysics, New Delhi (India); Singh, R.P.; Muralithar, S. [Inter University Accelerator Centre, New Delhi (India); Chakraborty, S.; Sharma, H.P. [Banaras Hindu University, Department of Physics, Varanasi (India); Kumar, A.; Govil, I.M. [Panjab University, Department of Physics, Chandigarh (India); Biswas, D.C. [Bhabha Atomic Research Center, Nuclear Physics Division, Trombay, Mumbai (India)

    2017-04-15

    Nuclear level lifetimes of high spin states in yrast and non-yrast bands of {sup 188}Pt nucleus have been measured using recoil distance plunger setup present at IUAC, Delhi. In the experiment nuclear states of interest were populated via {sup 174}Yb({sup 18}O,4n){sup 188}Pt reaction at a beam energy of 79MeV provided by 15 UD Pelletron accelerator. The extracted B(E2 ↓) values show an initial rise up to 4{sup +} state and then a nearly constant behavior with spin along yrast band, indicating change of nuclear structure in {sup 188}Pt at low spins. The good agreement between experimental and TPSM model B(E2 ↓) values up to 4{sup +} state suggests an increase in axial deformation of the nucleus. The average absolute β{sub 2} = 0.20 (3) obtained from measured B(E2 ↓) values matches well the values predicted by CHFB and IBM calculations for oblate (β{sub 2} ∝ -0.19) and prolate (β{sub 2} ∝ 0.22) shapes. As the lifetime measurements do not yield the sign of β{sub 2}, no definite conclusion can be drawn on the prolate or oblate collectivity of {sup 188}Pt on the basis of present measurements. (orig.)

  13. Gas Accretion in the M32 Nucleus: Past & Present

    CERN Document Server

    Seth, Anil C

    2010-01-01

    Using adaptive optics assisted Gemini/NIFS data, I study the present and past gas accretion in the central 3" of the M32 nucleus. From changes in the spectral slope and CO line depths near the center, I find evidence for unresolved dust emission resulting from BH accretion. With a luminosity of ~2e38 erg/s, this dust emission appears to be the most luminous tracer of current BH accretion, two orders of magnitude more luminous than previously detected X-ray emission. These observations suggest that using high resolution infrared data to search for dust emission may be an effective way to detect other nearby, low luminosity BHs, such as those in globular clusters. I also examine the fossil evidence of gas accretion contained in the kinematics of the stars in the nucleus. The higher-order moments (h3 and h4) of the line-of-sight velocity distribution show patterns that are remarkably similar to those seen on larger scales in elliptical galaxies and in gas-rich merger simulations. The kinematics suggests the pres...

  14. Volume regulation and shape bifurcation in the cell nucleus.

    Science.gov (United States)

    Kim, Dong-Hwee; Li, Bo; Si, Fangwei; Phillip, Jude M; Wirtz, Denis; Sun, Sean X

    2015-09-15

    Alterations in nuclear morphology are closely associated with essential cell functions, such as cell motility and polarization, and correlate with a wide range of human diseases, including cancer, muscular dystrophy, dilated cardiomyopathy and progeria. However, the mechanics and forces that shape the nucleus are not well understood. Here, we demonstrate that when an adherent cell is detached from its substratum, the nucleus undergoes a large volumetric reduction accompanied by a morphological transition from an almost smooth to a heavily folded surface. We develop a mathematical model that systematically analyzes the evolution of nuclear shape and volume. The analysis suggests that the pressure difference across the nuclear envelope, which is influenced by changes in cell volume and regulated by microtubules and actin filaments, is a major factor determining nuclear morphology. Our results show that physical and chemical properties of the extracellular microenvironment directly influence nuclear morphology and suggest that there is a direct link between the environment and gene regulation. © 2015. Published by The Company of Biologists Ltd.

  15. The nucleus accumbens beyond the anterior commissure: implications for psychosurgery.

    Science.gov (United States)

    Lucas-Neto, Lia; Mourato, Beatriz; Neto, Daniel; Oliveira, Edson; Martins, Hugo; Correia, Francisco; Gonçalves-Ferreira, António

    2014-01-01

    The nucleus accumbens (Acc) is a basal forebrain structure integrated in the dopaminergic cerebral rewarding circuits and implicated in some neuropsychiatric disorders. It has become a target for deep brain stimulation for some of these disorders when refractory to medical treatment. However, it is controversial as to which target is the best and similar results have been achieved with the stimulation of neighboring structures such as the bed nucleus of the stria terminalis (BNST). Previous studies have established the stereotactic anatomy of the human Acc, but some difficulties remain concerning its precise posterior limit, which is assumed to be at the level of the anterior commissure (AC). It is our purpose to clarify the anatomy of this zone, given the importance of its exact identification in psychosurgery. A total of 16 Acc were collected by autopsy, fixed, dissected, embedded and cut in coronal 5-µm slices. The slices were stained with hematoxylin and eosin, marked with anti-D1 and anti-D2 antibodies and analyzed under a microscope. The human Acc has the same cellular structure as the dorsal striatum, except in its posterior subcommissural part where voluminous neurons prevail, similar to and contiguous with the BNST. The Acc is longer than previously described, with a sub- and postcommissural extension behind the AC, continuous with the BNST. © 2014 S. Karger AG, Basel.

  16. Identifying folding nucleus based on residue contact networks of proteins.

    Science.gov (United States)

    Li, Jie; Wang, Jun; Wang, Wei

    2008-06-01

    In the native structure of a protein, all the residues are tightly parked together in a specific order following its folding and every residue contacts with some spatially neighbor residues. A residue contact network can be constructed by defining the residues as nodes and the native contacts as edges. During the folding of small single-domain proteins, there is a set of contacts (or bonds), defined as the folding nucleus (FN), which is formed around the transition state, i.e., a rate-limiting barrier located at about the middle between the unfolded states and the native state on the free energy landscape. Such a FN plays an essential role in the folding dynamics and the residues, which form the related contacts called as folding nucleus residues (FNRs). In this work, the FNRs in proteins are identified by using quantities which characterize the topology of residue contact networks of proteins. By comparing the specificities of residues with the network quantities K(R), L(R), and D(R), up to 90% FNRs of six typical proteins found experimentally are identified. It is found that the FNRs behave the full-closeness centrals rather than degree or closeness centers in the residue contact network, implying that they are important to the folding cooperativity of proteins. Our study shows that the FNRs can be identified solely from the native structures of proteins based on the analysis of residue contact network without any knowledge of the transition state ensemble. (c) 2008 Wiley-Liss, Inc.

  17. Monte Carlo Simulation for Statistical Decay of Compound Nucleus

    Directory of Open Access Journals (Sweden)

    Chadwick M.B.

    2012-02-01

    Full Text Available We perform Monte Carlo simulations for neutron and γ-ray emissions from a compound nucleus based on the Hauser-Feshbach statistical theory. This Monte Carlo Hauser-Feshbach (MCHF method calculation, which gives us correlated information between emitted particles and γ-rays. It will be a powerful tool in many applications, as nuclear reactions can be probed in a more microscopic way. We have been developing the MCHF code, CGM, which solves the Hauser-Feshbach theory with the Monte Carlo method. The code includes all the standard models that used in a standard Hauser-Feshbach code, namely the particle transmission generator, the level density module, interface to the discrete level database, and so on. CGM can emit multiple neutrons, as long as the excitation energy of the compound nucleus is larger than the neutron separation energy. The γ-ray competition is always included at each compound decay stage, and the angular momentum and parity are conserved. Some calculations for a fission fragment 140Xe are shown as examples of the MCHF method, and the correlation between the neutron and γ-ray is discussed.

  18. Evaluation of novel injectable hydrogels for nucleus pulposus replacement.

    Science.gov (United States)

    Vernengo, J; Fussell, G W; Smith, N G; Lowman, A M

    2008-01-01

    Branched copolymers composed of poly(N-isopropylacrylamide) (PNIPAAm) and poly(ethylene glycol) (PEG) are being investigated as an in situ forming replacement for the nucleus pulposus of the intervertebral disc. A family of copolymers was synthesized by varying the molecular weight of the PEG blocks and molar ratio of NIPAAm monomer units to PEG branches. Gel swelling, dissolution, and compressive mechanical properties were characterized over 90 days and stress relaxation behavior over 30 days immersion in vitro. It was found that the NIPAAm to PEG molar ratio did not affect the equilibrium swelling and compressive mechanical properties. However, gel elasticity exhibited a dependency on both the PEG block molecular weight and content. The equilibrium gel water content increased and compressive modulus decreased with increasing PEG block size. While all of the branched copolymers showed significant increases in stress relaxation time constant compared to the homopolymer (p < 0.05), the high PEG content PNIPAAm-PEG (4600 and 8000 g/mol) exhibited the maximum elasticity. Because of its high water content, requisite stiffness and high elastic response, PNIPAAm-PEG (4600 g/mol) will be further evaluated as a candidate material for nucleus pulposus replacement.

  19. Automatic leukocyte nucleus segmentation by intuitionistic fuzzy divergence based thresholding.

    Science.gov (United States)

    Jati, Arindam; Singh, Garima; Mukherjee, Rashmi; Ghosh, Madhumala; Konar, Amit; Chakraborty, Chandan; Nagar, Atulya K

    2014-03-01

    The paper proposes a robust approach to automatic segmentation of leukocyte's nucleus from microscopic blood smear images under normal as well as noisy environment by employing a new exponential intuitionistic fuzzy divergence based thresholding technique. The algorithm minimizes the divergence between the actual image and the ideally thresholded image to search for the final threshold. A new divergence formula based on exponential intuitionistic fuzzy entropy has been proposed. Further, to increase its noise handling capacity, a neighborhood-based membership function for the image pixels has been designed. The proposed scheme has been applied on 110 normal and 54 leukemia (chronic myelogenous leukemia) affected blood samples. The nucleus segmentation results have been validated by three expert hematologists. The algorithm achieves an average segmentation accuracy of 98.52% in noise-free environment. It beats the competitor algorithms in terms of several other metrics. The proposed scheme with neighborhood based membership function outperforms the competitor algorithms in terms of segmentation accuracy under noisy environment. It achieves 93.90% and 94.93% accuracies for Speckle and Gaussian noises, respectively. The average area under the ROC curves comes out to be 0.9514 in noisy conditions, which proves the robustness of the proposed algorithm.

  20. Black hole in the West Nucleus of Arp 220

    CERN Document Server

    Downes, D

    2007-01-01

    We present new observations with the IRAM Interferometer, in its longest-baseline configuration, of the CO(2-1) line and the 1.3mm dust radiation from the Arp 220 nuclear region. The dust source in the West nucleus has a size of 0.19 x 0.13 arcsec and a 1.3mm brightness temperature of 90K. This implies that the dust ring in the West nucleus has a high opacity, with tau = 1 at 1.1mm. Not only is the dust ring itself optically thick in the submm and far-IR, but it is surrounded by the previously-known, rapidly rotating molecular disk of size 0.5 arcsec that is also optically thick in the mid-IR. The molecular ring is cooler than the hot dust disk because the CO(2-1) line is seen in absorption against the dust disk. The dust ring is massive (1E9 solar masses), compact (radius 35pc), and hot (true dust temperature 170K). It resembles rather strikingly the dust ring detected around the quasar APM 08279+52, and is most unlike the warm, extended dust sources in starburst galaxies. Because there is a strong temperatu...

  1. Nucleus accumbens functional connectivity discriminates medication-overuse headache

    Directory of Open Access Journals (Sweden)

    D.M. Torta

    2016-01-01

    Full Text Available Medication-overuse headache (MOH is a secondary form of headache related to the overuse of triptans, analgesics and other acute headache medications. It is believed that MOH and substance addiction share some similar pathophysiological mechanisms. In this study we examined the whole brain resting state functional connectivity of the dorsal and ventral striatum in 30 patients (15 MOH and 15 non-MOH patients to investigate if classification algorithms can successfully discriminate between MOH and non-MOH patients on the basis of the spatial pattern of resting state functional connectivity of the dorsal and ventral striatal region of interest. Our results indicated that both nucleus accumbens and dorsal rostral putamen functional connectivity could discriminate between MOH and non-MOH patients, thereby providing possible support to two interpretations. First, that MOH patients show altered reward functionality in line with drug abusers (alterations in functional connectivity of the nucleus accumbens. Second, that MOH patients show inability to break habitual behavior (alterations in functional connectivity of the dorsal striatum. In conclusion, our data showed that MOH patients were characterized by an altered functional connectivity of motivational circuits at rest. These differences could permit the blind discrimination between the two conditions using classification algorithms. Considered overall, our findings might contribute to the development of novel diagnostic measures.

  2. Neutrino-nucleus reactions based on recent structure studies

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Toshio [Department of Physics and Graduate School of Integrated Basic Sciences, College of Humanities and Sciences, Nihon University, Sakurajosui 3-25-40, Setagaya-ku, Tokyo 156-8550 (Japan); National Astronomical Observatory of Japan, Mitaka, Tokyo 181-8588 (Japan)

    2015-05-15

    Neutrino-nucleus reactions are studied with the use of new shell model Hamiltonians, which have proper tensor components in the interactions and prove to be successful in the description of Gamow-Teller (GT) strengths in nuclei. The new Hamiltonians are applied to obtain new neutrino-nucleus reaction cross sections in {sup 12}C, {sup 13}C, {sup 56}Fe and {sup 56}Ni induced by solar and supernova neutrinos. The element synthesis by neutrino processes in supernova explosions is discussed with the new cross sections. The enhancement of the production yields of {sup 7}Li, {sup 11}B and {sup 55}Mn is obtained while fragmented GT strength in {sup 56}Ni with two-peak structure is found to result in smaller e-capture rates at stellar environments. The monopole-based universal interaction with tensor force of π+ρ meson exchanges is used to evaluate GT strength in {sup 40}Ar and ν-induced reactions on {sup 40}Ar. It is found to reproduce well the experimental GT strength in {sup 40}Ar.

  3. Formation of the avian nucleus magnocellularis from the auditory anlage.

    Science.gov (United States)

    Hendricks, Susan J; Rubel, Edwin W; Nishi, Rae

    2006-10-01

    In the avian auditory system, the neural network for computing the localization of sound in space begins with bilateral innervation of nucleus laminaris (NL) by nucleus magnocellularis (NM) neurons. We used antibodies against the neural specific markers Hu C/D, neurofilament, and SV2 together with retrograde fluorescent dextran labeling from the contralateral hindbrain to identify NM neurons within the anlage and follow their development. NM neurons could be identified by retrograde labeling as early as embryonic day (E) 6. While the auditory anlage organized itself into NM and NL in a rostral-to-caudal fashion between E6 and E8, labeled NM neurons were visible throughout the extent of the anlage at E6. By observing the pattern of neuronal rearrangements together with the pattern of contralaterally projecting NM fibers, we could identify NL in the ventral anlage. Ipsilateral NM fibers contacted the developing NL at E8, well after NM collaterals had projected contralaterally. Furthermore, the formation of ipsilateral connections between NM and NL neurons appeared to coincide with the arrival of VIIIth nerve fibers in NM. By E10, immunoreactivity for SV2 was heavily concentrated in the dorsal and ventral neuropils of NL. Thus, extensive pathfinding and morphological rearrangement of central auditory nuclei occurs well before the arrival of cochlear afferents. Our results suggest that NM neurons may play a central role in formation of tonotopic connections in the auditory system.

  4. Pilot biomechanical design of biomaterials for artificial nucleus prosthesis using 3D finite-element modeling

    Institute of Scientific and Technical Information of China (English)

    Qijin Huang; Guoquan Liu; Yong Li; Jin Gao; Zhengqiu Gu; Yuanzheng Ma; Haibin Xue

    2004-01-01

    Pilot biomechanical design of biomaterials for artificial nucleus prosthesis was carried out based on the 3D finite-element method. Two 3D models of lumbar intervertebral disc respectively with a real human nucleus and with the nucleus removed were developed and validated using published experimental and clinical data. Then the models with a stainless steel nucleus prosthesis implanted and with polymer nucleus prostheses of various properties implanted were used for the 3D finite-element biomechanical analysis. All the above simulation and analysis were carried out for the L4/L5 disc under a human worst-daily compression load of 2000 N. The results show that the polymer materials with Young's modulus of elasticity E = 0.1-100 MPa and Poisson's ratio v=0.35-0.5 are suitable to produce artificial nucleus prosthesis in view of biomechanical consideration.

  5. Critical nucleus size for disease-related polyglutamine aggregation is repeat length dependent

    Science.gov (United States)

    Kar, Karunakar; Jayaraman, Murali; Sahoo, Bankanidhi; Kodali, Ravindra; Wetzel, Ronald

    2010-01-01

    Since polyglutamine (polyQ) aggregate formation has been implicated as playing an important role in expanded CAG repeat diseases, it is important to understand the biophysics underlying the initiation of aggregation. Previously we showed that relatively long polyQ peptides aggregate by nucleated growth polymerization and a monomeric critical nucleus. We show here that, over a short repeat length range from Q26 to Q23, the size of the critical nucleus for aggregation increases from monomeric to dimeric to tetrameric. This variation in nucleus size suggests a common duplex anti-parallel β-sheet framework for the nucleus, and further supports the feasibility of an organized monomeric aggregation nucleus for longer polyQ repeat peptides. The data also suggest that a change in aggregation nucleus size may play a role in the pathogenicity of polyQ expansion in this series of familial neurodegenerative diseases. PMID:21317897

  6. Drill-and-crack technique for nuclear disassembly of hard nucleus.

    Science.gov (United States)

    Hwang, Ho Sik; Kim, Eun Chul; Kim, Man Soo

    2010-10-01

    We describe a new technique for nuclear disassembly of a hard nucleus in cataract surgery. The drill-and-crack technique, which combines phaco chop and the prechopper, makes a deep hole (drill) in the central nucleus with the phaco tip and divides the nucleus (crack) with the prechopper inside the hole. Copyright © 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  7. Tolerance to Sound Intensity of Binaural Coincidence Detection in the Nucleus Laminaris of the Owl

    OpenAIRE

    Peña, Jose Luis; Viete, Svenja; Albeck, Yehuda; Konishi, Masakazu

    1996-01-01

    Neurons of the owl's nucleus laminaris serve as coincidence detectors for measurement of interaural time difference. The discharge rate of nucleus laminaris neurons for both monaural and binaural stimulation increased with sound intensity until they reached an asymptote. Intense sounds affected neither the ratio between binaural and monaural responses nor the interaural time difference for which nucleus laminaris neurons were selective. Theoretical analysis showed that high afferent discharge...

  8. Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease.

    OpenAIRE

    Ferraye, Murielle; Debû, Bettina; Fraix, Valérie; Goetz, Laurent; Ardouin, Claire; Yelnik, Jérôme; Henry-Lagrange, Christelle; Seigneuret, Eric; Piallat, Brigitte; Krack, Paul; Le Bas, Jean-François; Benabid, Alim-Louis; Chabardès, Stephan; Pollak, Pierre

    2010-01-01

    International audience; Gait disturbances are frequent and disabling in advanced Parkinson's disease. These symptoms respond poorly to usual medical and surgical treatments but were reported to be improved by stimulation of the pedunculopontine nucleus. We studied the effects of stimulating the pedunculopontine nucleus area in six patients with severe freezing of gait, unresponsive to levodopa and subthalamic nucleus stimulation. Electrodes were implanted bilaterally in the pedunculopontine n...

  9. Study of the Pion Production Mechanisms in Nucleus-Nucleus Collisions at the CERN SC using the Omicron Spectrometer

    CERN Multimedia

    2002-01-01

    The aim of this experiment is to study the pion production mechanism in nucleus-nucleus collisions with the |3He and |1|2C beams of the CERN SC using the Omicron Spectrometer. The high intensity ion beams delivered now by the SC combined with the favourable characteristics of the Omicron Spectrometer offer a unique possibility of measuring very low cross-sections (typically in the order of 1 pb/(sr~MeV/c). In a first stage we will measure with an energy resolution of about 3~MeV the spectra of @p@+ emitted at 0|0 in two-body reactions induced by |3He ions of 910~MeV on targets of |6Li, |7Li, |9Be and |1|2C. The aim is to understand the reaction mechanisms and the nuclear wave functions most appropriate to describe the formation of nuclear bound states at momentum transfers of about 1.6@/1.7~GeV/c. The apparatus is shown in the figure. The same instrument will allow the measurement of the @p@+ inclusive spectra emitted at 0|0 after the interaction of the |1|2C|4|+ beam at 1032 MeV with the same targets. At 86 ...

  10. The Spectator-Induced Electromagnetic Effect on Meson Production in Nucleus-Nucleus Collisions at SPS Energies

    Directory of Open Access Journals (Sweden)

    Rybicki Andrzej

    2012-12-01

    Full Text Available The electromagnetic interaction between the spectator system and the charged mesons produced in the course of the high energy heavy ion collision was studied experimentally and theoretically in earlier works [1,2]. This effect was found to result in very large distortions of the final state spectra of the produced mesons [3] and to bring new information on the space-time evolution of the non-perturbative meson production process [4]. In this paper a more extended analysis of this effect will be presented, including a comparative study between charged meson spectra produced in Pb+Pb collisions as well as collisions of Pb ions with smaller nuclei. The experimental results will be compared with Monte Carlo simulations, giving a fair overall understanding of the interplay between the strong and the electromagnetic interaction in the heavy ion collision. A universal behaviour of charged meson spectra emerges from the above comparative study. This gives a unique chance of using the spectator charge as a tool to study the space-time evolution of the high energy nucleus-nucleus reaction.

  11. Medium effect in high-density nuclear matter probed by systematic analyses of nucleus-nucleus elastic scattering

    CERN Document Server

    Furumoto, T; Yamamoto, Y

    2016-01-01

    We investigate the property of the high-density nuclear matter probed by the nucleus-nucleus elastic scattering in the framework of the double-folding (DF) model with the complex $G$-matrix interaction. The medium effect including three-body-force (TBF) effect is investigated with present two methods based on the frozen density approximation. With the both methods, the medium effect in the high density region is clearly seen on the potential and the elastic cross section of the $^{16}$O + $^{16}$O system at $E/A =$ 70 MeV. The crucial role of the medium effect for the high-density nuclear matter is also confirmed with other effective nucleon-nucleon ($NN$) interactions. In addition, present methods are applied to other heavy-ion elastic scattering systems. Again, the medium effect in the high-density region is clearly seen in the heavy-ion elastic cross section. The effect on the elastic cross section becomes invisible with the increase of the target mass and the incident energy within existing the experiment...

  12. The suprachiasmatic nucleus changes the daily activity of the arcuate nucleus α-MSH neurons in male rats.

    Science.gov (United States)

    Guzmán-Ruiz, M; Saderi, N; Cazarez-Márquez, F; Guerrero-Vargas, N N; Basualdo, M C; Acosta-Galván, G; Buijs, R M

    2014-02-01

    Timing of metabolic processes is crucial for balanced physiology; many studies have shown the deleterious effects of untimely food intake. The basis for this might be an interaction between the arcuate nucleus (ARC) as the main integration site for metabolic information and the suprachiasmatic nucleus (SCN) as the master clock. Here we show in male rats that the SCN influences ARC daily neuronal activity by imposing a daily rhythm on the α-MSH neurons with a peak in neuronal activity at the end of the dark phase. Bilateral SCN lesions showed a complete disappearance of ARC neuronal rhythms and unilateral SCN lesions showed a decreased activation in the ARC at the lesioned side. Moreover light exposure during the dark phase inhibited ARC and α-MSH neuronal activity. The daily inhibition of ARC neuronal activity occurred in light-dark conditions as well as in dark-dark conditions, demonstrating the inhibitory effect to be mediated by increased SCN (subjective) day neuronal activity. Injections into the SCN with the neuronal tracer cholera toxin B showed that α-MSH neurons receive direct projections from the SCN. The present study demonstrates that the SCN activates and possibly also inhibits depending on the moment of the circadian cycle ARC α-MSH neurons via direct neuronal input. The persistence of these activity patterns in fasted animals demonstrates that this SCN-ARC interaction is not necessarily satiety associated but may support physiological functions associated with changes in the sleep-wake cycle.

  13. Role of the red nucleus in suppressing the jaw-opening reflex following stimulation of the raphe magnus nucleus.

    Science.gov (United States)

    Satoh, Yoshihide; Ishizuka, Ken'Ichi; Iwasaki, Shin-ichi

    2014-08-01

    In a previous study, we found that electrical and chemical stimulation of the red nucleus (RN) suppressed the high-threshold afferent-evoked jaw-opening reflex (JOR). It has been reported that the RN receives bilaterally projection fibers from the raphe magnus nucleus (RMg), and that stimulation of the RMg inhibits the tooth pulp-evoked nociceptive JOR. These facts imply that RMg-induced inhibition of the JOR could be mediated via the RN. The present study first examines whether stimulation of the RMg suppresses the high-threshold afferent-evoked JOR. The JOR was evoked by electrical stimulation of the inferior alveolar nerve (IAN), and was recorded as the electromyographic response of the anterior belly of the digastric muscle. The stimulus intensity was 4.0 (high-threshold) times the threshold. Conditioning electrical stimulation of the RMg significantly suppressed the JOR. A further study then examined whether electrically induced lesions of the RN or microinjection of muscimol into the RN affects RMg-induced suppression of the JOR. Electrically induced lesions of the bilateral RN and microinjection of muscimol into the bilateral RN both reduced the RMg-induced suppression of the JOR. These results suggest that RMg-induced suppression of the high-threshold afferent-evoked JOR is mediated by a relay in the RN.

  14. Heavy ion fusion: Possible dynamical solution of the problem of the abnormally large diffuseness of the nucleus-nucleus potential

    Science.gov (United States)

    Chushnyakova, M. V.; Gontchar, I. I.

    2013-01-01

    We attempt to make some progress in the problem of the apparently large diffuseness of the Woods-Saxon strong nucleus-nucleus interaction potential (SnnP) needed to fit a large number of precision fusion excitation functions. This problem has been formulated in Newton [Phys. Lett. B10.1016/j.physletb.2004.02.052 586, 219 (2004);Phys. Rev. C10.1103/PhysRevC.70.024605 70, 024605 (2004)]. We applied the classical dissipative trajectory model to describe the data on fusion (capture) of 16O with 92Zr, 144Sm, and 208Pb. No fluctuations or dynamical deformations of the interacting nuclei are accounted for. The friction force is supposed to be proportional to the squared derivative of the SnnP (the surface friction model). The SnnP is calculated within the framework of the double-folding model with the density-dependent M3Y NN forces. This potential is known to possess rather small diffuseness in contradistinction to what is required by the data analysis in Newton [Phys. Lett. B10.1016/j.physletb.2004.02.052 586, 219 (2004);Phys. Rev. C10.1103/PhysRevC.70.024605 70, 024605 (2004)]. Varying slightly the strength of radial friction (universally for all three reactions) and the diffuseness of the charge density of 208Pb we have obtained satisfactory agreement of the calculated excitation functions with the data.

  15. Rodent anxiety and kindling of the central amygdala and nucleus basalis.

    Science.gov (United States)

    Adamec, R; Shallow, T

    We studied lasting behavioral effects of kindling of three parts of the central nucleus of the amygdala and the anterior nucleus basalis in the right hemisphere of male Wistar rats. Kindling lastingly changed two measures of anxiety in the elevated plus-maze. The nature of the change depended on the location of the kindled focus. Kindling of the posterior central nucleus decreased both open-arm exploration and frequency of risk assessment in the elevated plus-maze 1 week after the fourth stage 5 seizure. Kindling of the middle parts of the central nucleus was without behavioral effects. Kindling of the anterior central nucleus and the anterior nucleus basalis increased risk assessment, which was interpreted as an anxiolytic effect. Changes in risk assessment produced by kindling of the central nucleus were dependent on open-arm avoidance, whereas the effects of nucleus basalis kindling were independent of open-arm avoidance. Analysis of covariance and factor analysis support the view that control of risk assessment is by circuitry, which is independent of that which controls open-arm avoidance. Moreover, part of this circuitry appears to involve the anterior nucleus basalis. Changes in plus-maze behavior were independent of changes in exploration or activity in either the plus-maze or hole board. These findings add to a growing body of evidence that suggests that subtle differences in location of a kindled focus within the rat amygdala lead to different behavioral outcomes.

  16. Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway

    Energy Technology Data Exchange (ETDEWEB)

    De Angelis Campos, Ana Carolina; Rodrigues, Michele Angela; Andrade, Carolina de; Miranda de Goes, Alfredo [Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, MG (Brazil); Nathanson, Michael H. [Department of Internal Medicine, Yale University School of Medicine, New Haven, CT (United States); Gomes, Dawidson A., E-mail: dawidson@icb.ufmg.br [Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, MG (Brazil)

    2011-08-26

    Highlights: {yields} EGF and its receptor translocates to the nucleus in liver cells. {yields} Real time imaging shows that EGF moves to the nucleus. {yields} EGF moves with its receptor to the nucleus. {yields} Dynamin and clathrin are necessary for EGFR nuclear translocation. -- Abstract: The epidermal growth factor (EGF) transduces its actions via the EGF receptor (EGFR), which can traffic from the plasma membrane to either the cytoplasm or the nucleus. However, the mechanism by which EGFR reaches the nucleus is unclear. To investigate these questions, liver cells were analyzed by immunoblot of cell fractions, confocal immunofluorescence and real time confocal imaging. Cell fractionation studies showed that EGFR was detectable in the nucleus after EGF stimulation with a peak in nuclear receptor after 10 min. Movement of EGFR to the nucleus was confirmed by confocal immunofluorescence and labeled EGF moved with the receptor to the nucleus. Small interference RNA (siRNA) was used to knockdown clathrin in order to assess the first endocytic steps of EGFR nuclear translocation in liver cells. A mutant dynamin (dynamin K44A) was also used to determine the pathways for this traffic. Movement of labeled EGF or EGFR to the nucleus depended upon dynamin and clathrin. This identifies the pathway that mediates the first steps for EGFR nuclear translocation in liver cells.

  17. Deuterium target data and precision neutrino-nucleus cross sections

    CERN Document Server

    Meyer, Aaron S; Gran, Richard; Hill, Richard J

    2016-01-01

    Amplitudes derived from scattering data on elementary targets are basic inputs to neutrino-nucleus cross section predictions. A prominent example is the isovector axial nucleon form factor, $F_A(q^2)$, which controls charged current signal processes at accelerator-based neutrino oscillation experiments. Previous extractions of $F_A$ from neutrino-deuteron scattering data rely on a dipole shape assumption that introduces an unquantified error. A new analysis of world data for neutrino-deuteron scattering is performed using a model-independent, and systematically improvable, representation of $F_A$. A complete error budget for the nucleon isovector axial radius leads to $r_A^2=0.46(22) \\,{\\rm fm}^2$, with a much larger uncertainty than determined in the original analyses. The quasielastic neutrino-neutron cross section is determined as $\\sigma(\

  18. Circadian rhythm. Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing.

    Science.gov (United States)

    Fernandez, Fabian; Lu, Derek; Ha, Phong; Costacurta, Patricia; Chavez, Renee; Heller, H Craig; Ruby, Norman F

    2014-11-14

    Chronic circadian dysfunction impairs declarative memory in humans but has little effect in common rodent models of arrhythmia caused by clock gene knockouts or surgical ablation of the suprachiasmatic nucleus (SCN). An important problem overlooked in these translational models is that human dysrhythmia occurs while SCN circuitry is genetically and neurologically intact. Siberian hamsters (Phodopus sungorus) are particularly well suited for translational studies because they can be made arrhythmic by a one-time photic treatment that severely impairs spatial and recognition memory. We found that once animals are made arrhythmic, subsequent SCN ablation completely rescues memory processing. These data suggest that the inhibitory effects of a malfunctioning SCN on cognition require preservation of circuitry between the SCN and downstream targets that are lost when these connections are severed.

  19. The ventral premammillary nucleus links leptin action and reproduction

    Directory of Open Access Journals (Sweden)

    Jose eDonato

    2011-10-01

    Full Text Available The amount of body fat and the energy balance are important factors that influence the timing of puberty and the normal reproductive function. Leptin is a key hormone that conveys to the central nervous system information about the individual energy reserve and modulates the hypothalamus-pituitary-gonad axis. Recent findings suggest that the ventral premammillary nucleus (PMV mediates the effects of leptin as a permissive factor for the onset of puberty and the coordinated secretion of luteinizing hormone during conditions of negative energy balance. Thus, in this review we will summarize the existing literature about the potential role played by PMV neurons in the regulation of the hypothalamus-pituitary-gonad axis.

  20. One-pion production in neutrino-nucleus collisions

    CERN Document Server

    Hernández, E; Vicente-Vacas, M J

    2013-01-01

    We use our model for neutrino pion production on the nucleon to study pion production on a nucleus. The model is conveniently modified to include in-medium corrections and its validity is extended up to 2 GeV neutrino energies by the inclusion of new resonant contributions in the production process. Our results are compared with recent MiniBooNE data measured in mineral oil. Our total cross sections are below data for neutrino energies above 1 GeV. As with other theoretical calculations, the agreement with data improves if we neglect pion final state interaction. This is also the case for differential cross sections convoluted over the neutrino flux.

  1. Mechanical and SEM analysis of artificial comet nucleus samples

    Science.gov (United States)

    Thiel, K.; Kochan, H.; Roessler, K.; Gruen, E.; Schwehm, G.; Hellmann, H.; Hsiung, P.; Koelzer, G.

    1989-01-01

    Since 1987 experiments dealing with comet nucleus phenomena have been carried out in the DFVLR space simulation chambers. The main objective of these experiments is a better understanding of thermal behavior, surface phenomena and especially the gas dust interaction. As a function of different sample compositions and exposure to solar irradiation (xenon-bulbs) crusts of different hardness and thickness were measured. The measuring device consists of a motor driven pressure foot (5 mm diameter), which is pressed into the sample. The applied compressive force is electronically monitored. The microstructure of the crust and dust residuals is investigated by scanning electron microscopy (SEM) techniques. Stress-depth profiles of an unirradiated and an irradiated model comet are given.

  2. In-beam spectroscopic studies of $^{44}$S nucleus

    CERN Document Server

    Caceres, L; Grévy, S; Sorlin, O; Dombradi, Zs; Bastin, B; Achouri, N L; Angélique, J C; Azaiez, F; Baiborodin, D; Borcea, R; Bourgeois, C; Buta, A; Bürger, A; Chapman, R; Dalouzy, J C; Dlouhy, Z; Drouard, A; Elekes, Z; Franchoo, S; Gaudefroy, L; Iacob, S; Laurent, B; Lazar, M; Liang, X; Liénard, E; Mrazek, J; Nalpas, L; Negoita, F; Nowacki, F; Orr, N A; Penionzhkevich, Y; Podolyak, Zs; Pougheon, F; Poves, A; Roussel-Chomaz, P; Saint-Laurent, M G; Stanoiu, M; Stefan, I

    2012-01-01

    The structure of the $^{44}$S nucleus has been studied at GANIL through the one proton knock-out reaction from a $^{45}$Cl secondary beam at 42 A$\\cdot$MeV. The $\\gamma$ rays following the de-excitation of $^{44}$S were detected in flight using the 70 BaF${_2}$ detectors of the Ch\\^{a}teau de Cristal array. An exhaustive $\\gamma\\gamma$-coincidence analysis allowed an unambiguous construction of the level scheme up to an excitation energy of 3301 keV. The existence of the spherical 2$^+_2$ state is confirmed and three new $\\gamma$-ray transitions connecting the prolate deformed 2$^+_1$ level were observed. Comparison of the experimental results to shell model calculations further supports a prolate and spherical shape coexistence with a large mixing of states built on the ground state band in $^{44}$S.

  3. One-pion production in neutrino-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Hernández, E. [Departamento de Física Fundamental e IUFFyM, Universidad de Salamanca, E-37008 Salamanca (Spain); Nieves, J. [Instituto de Física Corpuscular (IFIC), Centro Mixto CSIC-Universidad de Valencia, Institutos de Investigación de Paterna, Apartado 22085, E-46071 Valencia (Spain); Vicente-Vacas, J. M. [Departamento de Física Teórica e IFIC, Centro Mixto Universidad de Valencia-CSIC, Institutos de Investigación de Paterna, Apartado 22085, E-46071 Valencia (Spain)

    2015-05-15

    We use our model for neutrino pion production on the nucleon to study pion production on a nucleus. The model is conveniently modified to include in-medium corrections and its validity is extended up to 2 GeV neutrino energies by the inclusion of new resonant contributions in the production process. Our results are compared with recent MiniBooNE data measured in mineral oil. Our total cross sections are below data for neutrino energies above ≈ 1 GeV. As with other theoretical calculations, the agreement with data improves if we neglect pion final state interaction. This is also the case for differential cross sections convoluted over the neutrino flux.

  4. Band Structure in the Doubly Magic Nucleus 56Ni

    Institute of Scientific and Technical Information of China (English)

    DONG Bao-Guo; GUO Hong-Chao

    2004-01-01

    @@ Band structures near yrast lines of the Z = N doubly magic nucleus 56Ni are investigated with the configurationdependent cranked Nilsson-Strutinsky approach. The observed deformed bands are confirmed as highly deformed and their properties are explained theoretically. The calculated transition quadrupole moments Qt, ~ 1.7 eb at low spin as well as the kinematic and dynamic moments of inertia J1) and J(2) for configurations of interest are found to be generally in good agreement with the observed results. Two terminating states at 20+ and 29- for the two observed bands and other terminations in 56Ni are also predicted. It is found that the configuration-dependent cranked Nilsson-Strutinsky approach is better in the description of nuclear properties and band structures at high spin than other models.

  5. The LHC as a Proton-Nucleus Collider

    CERN Document Server

    Carli, C

    2006-01-01

    Following its initial operation as a proton-proton (p-p) and heavy-ion (208Pb82+-208Pb82+) collider, the LHC is expected to operate as a p-Pb collider. Later it may collide protons with other lighter nuclei such as 40Ar18+ or 16O8+. We show how the existing proton and lead-ion injector chains may be efficiently operated in tandem to provide these hybrid collisions. The two-in-one magnet design of the LHC main rings imposes different revolution frequencies for the two beams in part of the magnetic cycle. We discuss and evaluate the consequences for beam dynamics and estimate the potential performance of the LHC as a proton-nucleus collider.

  6. Observation of top quark production in proton-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Sirunyan, Albert M; et al.

    2017-09-21

    The first observation of top quark production in proton-nucleus collisions is reported using proton-lead data collected by the CMS experiment at the CERN LHC at a nucleon-nucleon center-of-mass energy of $\\sqrt{s_\\mathrm{NN}} =$ 8.16 TeV. The measurement is performed using events with exactly one isolated electron or muon and at least four jets. The data sample corresponds to an integrated luminosity of 174 nb$^{-1}$. The significance of the $\\mathrm{t}\\overline{\\mathrm{t}}$ signal against the background-only hypothesis is above five standard deviations. The measured cross section is $\\sigma_{\\mathrm{t}\\overline{\\mathrm{t}}} =$ 45$\\pm$8 nb, consistent with predictions from perturbative quantum chromodynamics.

  7. Highlight on the dynamic organization of the nucleus

    Science.gov (United States)

    2017-01-01

    ABSTRACT The last decade has seen rapid advances in our understanding of the proteins of the nuclear envelope, which have multiple roles including positioning the nucleus, maintaining its structural organization, and in events ranging from mitosis and meiosis to chromatin positioning and gene expression. Diverse new and stimulating results relating to nuclear organization and genome function from across kingdoms were presented in a session stream entitled “Dynamic Organization of the Nucleus” at this year's Society of Experimental Biology (SEB) meeting in Brighton, UK (July 2016). This was the first session stream run by the Nuclear Dynamics Special Interest Group, which was organized by David Evans, Katja Graumann (both Oxford Brookes University, UK) and Iris Meier (Ohio State University, USA). The session featured presentations on areas relating to nuclear organization across kingdoms including the nuclear envelope, chromatin organization, and genome function. PMID:27715428

  8. Collective Bands in Neutron-Rich 104Mo Nucleus

    Institute of Scientific and Technical Information of China (English)

    杨利明; 姜卓; 全明吉; J. H. Hamilton; A. V. Ramayya; J. K. Hwang; X. Q. Zhang; B. R. S. Babu; J. Komicki; E. F. Jones; W. C. Ma; 朱胜江; J. D. Cole; R. Aryaeinejad; M. W. Drigert; I. Y. Lee; J. O. Rasmussen; M. A. Stover; G. M. Ter-Akopian; A. V. Daniel; 李科; 朱凌燕; 甘翠云; 萨哈伊; 龙桂鲁; 许瑞清; 张征

    2001-01-01

    Levels in the neutron-rich 104Mo nucleus have been investigated by observing prompt γ-rays from the spontaneous fission of 252Cf with the Gammasphere detector array. The ground-state band, the one-phonon and the twophonon γ-vibrational bands as well as a quasiparticle band have been confirmed and expanded with spin up to 14h. Other two side bands probably built on new quasiparticle states are identified. The possible configurations for the quasiparticle bands are discussed. Two of the quasiparticle bands show larger moments of inertia and may have pair-free characteristics. The levels of the ground-state band, the one-phonon γ-band and the two-phonon γ-band calculated from a general collective model are in close agreement with the experimental data.

  9. Superficial stellate cells of the dorsal cochlear nucleus

    Directory of Open Access Journals (Sweden)

    Pierre F. Apostolides

    2014-06-01

    Full Text Available The dorsal cochlear nucleus (DCN integrates auditory and multisensory signals at the earliest levels of auditory processing. Proposed roles for this region include sound localization in the vertical plane, head orientation to sounds of interest, and suppression of sensitivity to expected sounds. Auditory and non-auditory information streams to the DCN are refined by a remarkably complex array of inhibitory and excitatory interneurons, and the role of each cell type is gaining increasing attention. One inhibitory neuron that has been poorly appreciated to date is the superficial stellate cell. Here we review previous studies and describe new results that reveal the surprisingly rich interactions that this tiny interneuron has with its neighbors, interactions which enable it to respond to both multisensory and auditory afferents.

  10. Input/output properties of the lateral vestibular nucleus

    Science.gov (United States)

    Boyle, R.; Bush, G.; Ehsanian, R.

    2004-01-01

    This article is a review of work in three species, squirrel monkey, cat, and rat studying the inputs and outputs from the lateral vestibular nucleus (LVN). Different electrophysiological shock paradigms were used to determine the synaptic inputs derived from thick to thin diameter vestibular nerve afferents. Angular and linear mechanical stimulations were used to activate and study the combined and individual contribution of inner ear organs and neck afferents. The spatio-temporal properties of LVN neurons in the decerebrated rat were studied in response to dynamic acceleration inputs using sinusoidal linear translation in the horizontal head plane. Outputs were evaluated using antidromic identification techniques and identified LVN neurons were intracellularly injected with biocytin and their morphology studied.

  11. Relativistic models for quasielastic electron and neutrino-nucleus scattering

    Directory of Open Access Journals (Sweden)

    Meucci Andrea

    2012-12-01

    Full Text Available Relativistic models developed within the framework of the impulse approximation for quasielastic (QE electron scattering and successfully tested in comparison with electron-scattering data have been extended to neutrino-nucleus scattering. Different descriptions of final-state interactions (FSI in the inclusive scattering are compared. In the relativistic Green’s function (RGF model FSI are described consistently with the exclusive scattering using a complex optical potential. In the relativistic mean field (RMF model FSI are described by the same RMF potential which gives the bound states. The results of the models are compared for electron and neutrino scattering and, for neutrino scattering, with the recently measured charged-current QE (CCQE MiniBooNE cross sections.

  12. Dynamical Analysis of Protein Regulatory Network in Budding Yeast Nucleus

    Institute of Scientific and Technical Information of China (English)

    LI Fang-Ting; JIA Xun

    2006-01-01

    @@ Recent progresses in the protein regulatory network of budding yeast Saccharomyces cerevisiae have provided a global picture of its protein network for further dynamical research. We simplify and modularize the protein regulatory networks in yeast nucleus, and study the dynamical properties of the core 37-node network by a Boolean network model, especially the evolution steps and final fixed points. Our simulation results show that the number of fixed points N(k) for a given size of the attraction basin k obeys a power-law distribution N(k)∝k-2.024. The yeast network is more similar to a scale-free network than a random network in the above dynamical properties.

  13. Transcription in the context of the 3D nucleus.

    Science.gov (United States)

    Wendt, Kerstin S; Grosveld, Frank G

    2014-04-01

    Gene activity is not only determined by processes occurring very close to or at the gene, such as transcription factor or RNA Polymerase II (PolII) binding. A multitude of past observations such as the localization of inactive chromatin to the nuclear periphery and active chromatin in the centre of the nucleus, the clustering of highly transcribed genes at transcriptional hotspots as well as the looping of active genes out of the chromosome territory made clear that the 'context matters' and the 3-dimensional organization of the chromatin fibre is fundamental for genome function. Here we want to review whether and how the different architectural levels that were recently identified by high-throughput chromatin conformation capturing techniques influence transcription.

  14. Neutrino-Nucleus Reactions and Muon Capture in 12C

    CERN Document Server

    Krmpotic, F; Mariano, A; Mariano, and A.

    2004-01-01

    The neutrino-nucleus cross section and the muon capture rate are discussed within a simple formalism which facilitates the nuclear structure calculations. The corresponding formulae only depend on four types of nuclear matrix elements, which are currently used in the nuclear beta decay. We have also considered the non-locality effects arising from the velocity-dependent terms in the hadronic current. We show that for both observables in 12C the higher order relativistic corrections are of the order of ~5 only, and therefore do not play a significant role. As nuclear model framework we use the projected QRPA (PQRPA) and show that the number projection plays a crucial role in removing the degeneracy between the proton-neutron two quasiparticle states at the level of the mean field. Comparison is done with both the experimental data and the previous shell model calculations. Possible consequences of the present study on the determination of the $\

  15. Quantum Monte Carlo Calculations of Nucleon-Nucleus Scattering

    Science.gov (United States)

    Wiringa, R. B.; Nollett, Kenneth M.; Pieper, Steven C.; Brida, I.

    2009-10-01

    We report recent quantum Monte Carlo (variational and Green's function) calculations of elastic nucleon-nucleus scattering. We are adding the cases of proton-^4He, neutron-^3H and proton-^3He scattering to a previous GFMC study of neutron-^4He scattering [1]. To do this requires generalizing our methods to include long-range Coulomb forces and to treat coupled channels. The two four-body cases can be compared to other accurate four-body calculational methods such as the AGS equations and hyperspherical harmonic expansions. We will present results for the Argonne v18 interaction alone and with Urbana and Illinois three-nucleon potentials. [4pt] [1] K.M. Nollett, S. C. Pieper, R.B. Wiringa, J. Carlson, and G.M. Hale, Phys. Rev. Lett. 99, 022502 (2007)

  16. Failure of the statistical hypothesis for compound nucleus decay

    Energy Technology Data Exchange (ETDEWEB)

    Chrien, R E

    1976-01-01

    In the past five years, conclusive evidence has accumulated that channel correlations are important in resonance reactions. Experiments showing the failure of the statistical hypothesis for compound nucleus decay are described. The emphasis is on the radiative neutron capture reaction, where much detailed work has been done. A short summary of the theory of the (n,..gamma..) reaction is presented; it is demonstrated that this reaction is a sensitive probe of the wave functions for highly excited nuclear states. Various experimental techniques using reactor and accelerator-based neutron sources are presented. The experiments have shown that both resonant and non-resonant reactions can show single particle effects where the external part of configuration space is dominant. In the non-resonant case, hard sphere capture is important; on resonances, valence particle motion and the contributions of 1 and 3 quasi-particle doorway states make up a significant fraction of the radiative width.

  17. Traces of the Θ+ Pentaquark in K+-Nucleus Dynamics

    Science.gov (United States)

    Gal, A.; Friedman, E.

    2005-02-01

    Long-standing anomalies in K+-nucleus integral cross sections could be resolved by extending the impulse-approximation tρ optical-potential framework to incorporate K+ absorption on pairs of nucleons. Substantially improved fits to the data at plab˜500 700 MeV/c are obtained. An upper bound on the absorption cross section per nucleon is derived, σabs(K+)/A˜3.5 mb. We conjecture that the underlying microscopic absorption process is K+nN→Θ+N, where Θ+(1540) is the newly discovered exotic Y=2, I=0, Z=1 pentaquark baryon, and estimate that σ(K+d→Θ+p) is a fraction of millibarn. Comments are made on Θ+ production reactions on nuclei.

  18. Ferrofluid nucleus phase transitions in an external uniform magnetic field

    Institute of Scientific and Technical Information of China (English)

    B. M. Tanygin; S. I. Shulyma; V. F. Kovalenko; M. V. Petrychuk

    2015-01-01

    The phase transition between a massive dense phase and a diluted superparamagnetic phase has been studied by means of a direct molecular dynamics simulation. The equilibrium structures of the ferrofluid aggregate nucleus are obtained for different values of a temperature and an external magnetic field magnitude. An approximate match of experiment and simulation has been shown for the ferrofluid phase diagram coordinates “field–temperature”. The provided phase coexistence curve has an opposite trend comparing to some of known theoretical results. This contradiction has been discussed. For given experimental parameters, it has been concluded that the present results describe more precisely the transition from linear chains to a dense globes phase. The theoretical concepts which provide the opposite binodal curve dependency trend match other experimental conditions:a diluted ferrofluid, a high particle coating rate, a high temperature, and/or a less particles coupling constant value.

  19. Observation of top quark production in proton-nucleus collisions

    CERN Document Server

    Sirunyan, Albert M; CMS Collaboration; Adam, Wolfgang; Ambrogi, Federico; Asilar, Ece; Bergauer, Thomas; Brandstetter, Johannes; Brondolin, Erica; Dragicevic, Marko; Erö, Janos; Escalante Del Valle, Alberto; Flechl, Martin; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Grossmann, Johannes; Hrubec, Josef; Jeitler, Manfred; König, Axel; Krammer, Natascha; Krätschmer, Ilse; Liko, Dietrich; Madlener, Thomas; Mikulec, Ivan; Pree, Elias; Rad, Navid; Rohringer, Herbert; Schieck, Jochen; Schöfbeck, Robert; Spanring, Markus; Spitzbart, Daniel; Waltenberger, Wolfgang; Wittmann, Johannes; Wulz, Claudia-Elisabeth; Zarucki, Mateusz; Chekhovsky, Vladimir; Mossolov, Vladimir; Suarez Gonzalez, Juan; De Wolf, Eddi A; Di Croce, Davide; Janssen, Xavier; Lauwers, Jasper; Van De Klundert, Merijn; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Abu Zeid, Shimaa; Blekman, Freya; D'Hondt, Jorgen; De Bruyn, Isabelle; De Clercq, Jarne; Deroover, Kevin; Flouris, Giannis; Lontkovskyi, Denys; Lowette, Steven; Marchesini, Ivan; Moortgat, Seth; Moreels, Lieselotte; Python, Quentin; Skovpen, Kirill; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Parijs, Isis; Beghin, Diego; Bilin, Bugra; Brun, Hugues; Clerbaux, Barbara; De Lentdecker, Gilles; Delannoy, Hugo; Dorney, Brian; Fasanella, Giuseppe; Favart, Laurent; Goldouzian, Reza; Grebenyuk, Anastasia; Kalsi, Amandeep Kaur; Lenzi, Thomas; Luetic, Jelena; Maerschalk, Thierry; Marinov, Andrey; Seva, Tomislav; Starling, Elizabeth; Vander Velde, Catherine; Vanlaer, Pascal; Vannerom, David; Yonamine, Ryo; Zenoni, Florian; Cornelis, Tom; Dobur, Didar; Fagot, Alexis; Gul, Muhammad; Khvastunov, Illia; Poyraz, Deniz; Roskas, Christos; Salva Diblen, Sinem; Tytgat, Michael; Verbeke, Willem; Zaganidis, Nicolas; Bakhshiansohi, Hamed; Bondu, Olivier; Brochet, Sébastien; Bruno, Giacomo; Caputo, Claudio; Caudron, Adrien; David, Pieter; De Visscher, Simon; Delaere, Christophe; Delcourt, Martin; Francois, Brieuc; Giammanco, Andrea; Komm, Matthias; Krintiras, Georgios; Lemaitre, Vincent; Magitteri, Alessio; Mertens, Alexandre; Musich, Marco; Piotrzkowski, Krzysztof; Quertenmont, Loic; Saggio, Alessia; Vidal Marono, Miguel; Wertz, Sébastien; Zobec, Joze; Aldá Júnior, Walter Luiz; Alves, Fábio Lúcio; Alves, Gilvan; Brito, Lucas; Correa Martins Junior, Marcos; Hensel, Carsten; Moraes, Arthur; Pol, Maria Elena; Rebello Teles, Patricia; Belchior Batista Das Chagas, Ewerton; Carvalho, Wagner; Chinellato, Jose; Coelho, Eduardo; Melo Da Costa, Eliza; Da Silveira, Gustavo Gil; De Jesus Damiao, Dilson; Fonseca De Souza, Sandro; Huertas Guativa, Lina Milena; Malbouisson, Helena; Melo De Almeida, Miqueias; Mora Herrera, Clemencia; Mundim, Luiz; Nogima, Helio; Sanchez Rosas, Luis Junior; Santoro, Alberto; Sznajder, Andre; Thiel, Mauricio; Tonelli Manganote, Edmilson José; Torres Da Silva De Araujo, Felipe; Vilela Pereira, Antonio; Ahuja, Sudha; Bernardes, Cesar Augusto; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Romero Abad, David; Ruiz Vargas, José Cupertino; Aleksandrov, Aleksandar; Hadjiiska, Roumyana; Iaydjiev, Plamen; Misheva, Milena; Rodozov, Mircho; Shopova, Mariana; Sultanov, Georgi; Dimitrov, Anton; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Fang, Wenxing; Gao, Xuyang; Yuan, Li; Ahmad, Muhammad; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Chen, Ye; Jiang, Chun-Hua; Leggat, Duncan; Liao, Hongbo; Liu, Zhenan; Romeo, Francesco; Shaheen, Sarmad Masood; Spiezia, Aniello; Tao, Junquan; Wang, Chunjie; Wang, Zheng; Yazgan, Efe; Zhang, Huaqiao; Zhang, Sijing; Zhao, Jingzhou; Ban, Yong; Chen, Geng; Li, Jing; Li, Qiang; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Xu, Zijun; Zhang, Fengwangdong; Wang, Yi; Avila, Carlos; Cabrera, Andrés; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; González Hernández, Carlos Felipe; Ruiz Alvarez, José David; Segura Delgado, Manuel Alejandro; Courbon, Benoit; Godinovic, Nikola; Lelas, Damir; Puljak, Ivica; Ribeiro Cipriano, Pedro M; Sculac, Toni; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Ferencek, Dinko; Kadija, Kreso; Mesic, Benjamin; Starodumov, Andrei; Susa, Tatjana; Ather, Mohsan Waseem; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Rykaczewski, Hans; Finger, Miroslav; Finger Jr, Michael; Carrera Jarrin, Edgar; Assran, Yasser; Elgammal, Sherif; Mahrous, Ayman; Dewanjee, Ram Krishna; Kadastik, Mario; Perrini, Lucia; Raidal, Martti; Tiko, Andres; Veelken, Christian; Eerola, Paula; Kirschenmann, Henning; Pekkanen, Juska; Voutilainen, Mikko; Havukainen, Joona; Heikkilä, Jaana Kristiina; Jarvinen, Terhi; Karimäki, Veikko; Kinnunen, Ritva; Lampén, Tapio; Lassila-Perini, Kati; Laurila, Santeri; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Siikonen, Hannu; Tuominen, Eija; Tuominiemi, Jorma; Tuuva, Tuure; Besancon, Marc; Couderc, Fabrice; Dejardin, Marc; Denegri, Daniel; Faure, Jean-Louis; Ferri, Federico; Ganjour, Serguei; Ghosh, Saranya; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Kucher, Inna; Leloup, Clément; Locci, Elizabeth; Machet, Martina; Malcles, Julie; Negro, Giulia; Rander, John; Rosowsky, André; Sahin, Mehmet Özgür; Titov, Maksym; Abdulsalam, Abdulla; Amendola, Chiara; Antropov, Iurii; Baffioni, Stephanie; Beaudette, Florian; Busson, Philippe; Cadamuro, Luca; Charlot, Claude; Granier de Cassagnac, Raphael; Jo, Mihee; Lisniak, Stanislav; Lobanov, Artur; Martin Blanco, Javier; Nguyen, Matthew; Ochando, Christophe; Ortona, Giacomo; Paganini, Pascal; Pigard, Philipp; Salerno, Roberto; Sauvan, Jean-Baptiste; Sirois, Yves; Stahl Leiton, Andre Govinda; Strebler, Thomas; Yilmaz, Yetkin; Zabi, Alexandre; Zghiche, Amina; Agram, Jean-Laurent; Andrea, Jeremy; Bloch, Daniel; Brom, Jean-Marie; Buttignol, Michael; Chabert, Eric Christian; Chanon, Nicolas; Collard, Caroline; Conte, Eric; Coubez, Xavier; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Jansová, Markéta; Le Bihan, Anne-Catherine; Tonon, Nicolas; Van Hove, Pierre; Gadrat, Sébastien; Beauceron, Stephanie; Bernet, Colin; Boudoul, Gaelle; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fay, Jean; Finco, Linda; Gascon, Susan; Gouzevitch, Maxime; Grenier, Gérald; Ille, Bernard; Lagarde, Francois; Laktineh, Imad Baptiste; Lethuillier, Morgan; Mirabito, Laurent; Pequegnot, Anne-Laure; Perries, Stephane; Popov, Andrey; Sordini, Viola; Vander Donckt, Muriel; Viret, Sébastien; Toriashvili, Tengizi; Bagaturia, Iuri; Autermann, Christian; Feld, Lutz; Kiesel, Maximilian Knut; Klein, Katja; Lipinski, Martin; Preuten, Marius; Schomakers, Christian; Schulz, Johannes; Teroerde, Marius; Zhukov, Valery; Albert, Andreas; Dietz-Laursonn, Erik; Duchardt, Deborah; Endres, Matthias; Erdmann, Martin; Erdweg, Sören; Esch, Thomas; Fischer, Robert; Güth, Andreas; Hamer, Matthias; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Knutzen, Simon; Merschmeyer, Markus; Meyer, Arnd; Millet, Philipp; Mukherjee, Swagata; Pook, Tobias; Radziej, Markus; Reithler, Hans; Rieger, Marcel; Scheuch, Florian; Teyssier, Daniel; Thüer, Sebastian; Flügge, Günter; Kargoll, Bastian; Kress, Thomas; Künsken, Andreas; Müller, Thomas; Nehrkorn, Alexander; Nowack, Andreas; Pistone, Claudia; Pooth, Oliver; Stahl, Achim; Aldaya Martin, Maria; Arndt, Till; Asawatangtrakuldee, Chayanit; Beernaert, Kelly; Behnke, Olaf; Behrens, Ulf; Bermúdez Martínez, Armando; Bin Anuar, Afiq Aizuddin; Borras, Kerstin; Botta, Valeria; Campbell, Alan; Connor, Patrick; Contreras-Campana, Christian; Costanza, Francesco; Diez Pardos, Carmen; Eckerlin, Guenter; Eckstein, Doris; Eichhorn, Thomas; Eren, Engin; Gallo, Elisabetta; Garay Garcia, Jasone; Geiser, Achim; Grados Luyando, Juan Manuel; Grohsjean, Alexander; Gunnellini, Paolo; Guthoff, Moritz; Harb, Ali; Hauk, Johannes; Hempel, Maria; Jung, Hannes; Kasemann, Matthias; Keaveney, James; Kleinwort, Claus; Korol, Ievgen; Krücker, Dirk; Lange, Wolfgang; Lelek, Aleksandra; Lenz, Teresa; Leonard, Jessica; Lipka, Katerina; Lohmann, Wolfgang; Mankel, Rainer; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mittag, Gregor; Mnich, Joachim; Mussgiller, Andreas; Ntomari, Eleni; Pitzl, Daniel; Raspereza, Alexei; Savitskyi, Mykola; Saxena, Pooja; Shevchenko, Rostyslav; Stefaniuk, Nazar; Van Onsem, Gerrit Patrick; Walsh, Roberval; Wen, Yiwen; Wichmann, Katarzyna; Wissing, Christoph; Zenaiev, Oleksandr; Aggleton, Robin; Bein, Samuel; Blobel, Volker; Centis Vignali, Matteo; Dreyer, Torben; Garutti, Erika; Gonzalez, Daniel; Haller, Johannes; Hinzmann, Andreas; Hoffmann, Malte; Karavdina, Anastasia; Klanner, Robert; Kogler, Roman; Kovalchuk, Nataliia; Kurz, Simon; Lapsien, Tobias; Marconi, Daniele; Meyer, Mareike; Niedziela, Marek; Nowatschin, Dominik; Pantaleo, Felice; Peiffer, Thomas; Perieanu, Adrian; Scharf, Christian; Schleper, Peter; Schmidt, Alexander; Schumann, Svenja; Schwandt, Joern; Sonneveld, Jory; Stadie, Hartmut; Steinbrück, Georg; Stober, Fred-Markus Helmut; Stöver, Marc; Tholen, Heiner; Troendle, Daniel; Usai, Emanuele; Vanhoefer, Annika; Vormwald, Benedikt; Akbiyik, Melike; Barth, Christian; Baselga, Marta; Baur, Sebastian; Butz, Erik; Caspart, René; Chwalek, Thorsten; Colombo, Fabio; De Boer, Wim; Dierlamm, Alexander; Faltermann, Nils; Freund, Benedikt; Friese, Raphael; Giffels, Manuel; Harrendorf, Marco Alexander; Hartmann, Frank; Heindl, Stefan Michael; Husemann, Ulrich; Kassel, Florian; Kudella, Simon; Mildner, Hannes; Mozer, Matthias Ulrich; Müller, Thomas; Plagge, Michael; Quast, Gunter; Rabbertz, Klaus; Schröder, Matthias; Shvetsov, Ivan; Sieber, Georg; Simonis, Hans-Jürgen; Ulrich, Ralf; Wayand, Stefan; Weber, Marc; Weiler, Thomas; Williamson, Shawn; Wöhrmann, Clemens; Wolf, Roger; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Kyriakis, Aristotelis; Loukas, Demetrios; Topsis-Giotis, Iasonas; Karathanasis, George; Kesisoglou, Stilianos; Panagiotou, Apostolos; Saoulidou, Niki; Kousouris, Konstantinos; Evangelou, Ioannis; Foudas, Costas; Gianneios, Paraskevas; Katsoulis, Panagiotis; Kokkas, Panagiotis; Mallios, Stavros; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Strologas, John; Triantis, Frixos A; Tsitsonis, Dimitrios; Csanad, Mate; Filipovic, Nicolas; Pasztor, Gabriella; Surányi, Olivér; Veres, Gabor Istvan; Bencze, Gyorgy; Hajdu, Csaba; Horvath, Dezso; Hunyadi, Ádám; Sikler, Ferenc; Veszpremi, Viktor; Beni, Noemi; Czellar, Sandor; Karancsi, János; Makovec, Alajos; Molnar, Jozsef; Szillasi, Zoltan; Bartók, Márton; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Choudhury, Somnath; Komaragiri, Jyothsna Rani; Bahinipati, Seema; Bhowmik, Sandeep; Mal, Prolay; Mandal, Koushik; Nayak, Aruna; Sahoo, Deepak Kumar; Sahoo, Niladribihari; Swain, Sanjay Kumar; Bansal, Sunil; Beri, Suman Bala; Bhatnagar, Vipin; Chawla, Ridhi; Dhingra, Nitish; Kaur, Anterpreet; Kaur, Manjit; Kaur, Sandeep; Kumar, Ramandeep; Kumari, Priyanka; Mehta, Ankita; Singh, Jasbir; Walia, Genius; Kumar, Ashok; Shah, Aashaq; Bhardwaj, Ashutosh; Chauhan, Sushil; Choudhary, Brajesh C; Garg, Rocky Bala; Keshri, Sumit; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Ramkrishna; Bhardwaj, Rishika; Bhattacharya, Rajarshi; Bhattacharya, Satyaki; Bhawandeep, Bhawandeep; Dey, Sourav; Dutt, Suneel; Dutta, Suchandra; Ghosh, Shamik; Majumdar, Nayana; Modak, Atanu; Mondal, Kuntal; Mukhopadhyay, Supratik; Nandan, Saswati; Purohit, Arnab; Roy, Ashim; Roy Chowdhury, Suvankar; Sarkar, Subir; Sharan, Manoj; Thakur, Shalini; Behera, Prafulla Kumar; Chudasama, Ruchi; Dutta, Dipanwita; Jha, Vishwajeet; Kumar, Vineet; Mohanty, Ajit Kumar; Netrakanti, Pawan Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Dugad, Shashikant; Mahakud, Bibhuprasad; Mitra, Soureek; Mohanty, Gagan Bihari; Sur, Nairit; Sutar, Bajrang; Banerjee, Sudeshna; Bhattacharya, Soham; Chatterjee, Suman; Das, Pallabi; Guchait, Monoranjan; Jain, Sandhya; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Sarkar, Tanmay; Wickramage, Nadeesha; Chauhan, Shubhanshu; Dube, Sourabh; Hegde, Vinay; Kapoor, Anshul; Kothekar, Kunal; Pandey, Shubham; Rane, Aditee; Sharma, Seema; Chenarani, Shirin; Eskandari Tadavani, Esmaeel; Etesami, Seyed Mohsen; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Rezaei Hosseinabadi, Ferdos; Safarzadeh, Batool; Zeinali, Maryam; Felcini, Marta; Grunewald, Martin; Abbrescia, Marcello; Calabria, Cesare; Colaleo, Anna; Creanza, Donato; Cristella, Leonardo; De Filippis, Nicola; De Palma, Mauro; Errico, Filippo; Fiore, Luigi; Iaselli, Giuseppe; Lezki, Samet; Maggi, Giorgio; Maggi, Marcello; Miniello, Giorgia; My, Salvatore; Nuzzo, Salvatore; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Ranieri, Antonio; Selvaggi, Giovanna; Sharma, Archana; Silvestris, Lucia; Venditti, Rosamaria; Verwilligen, Piet; Abbiendi, Giovanni; Battilana, Carlo; Bonacorsi, Daniele; Borgonovi, Lisa; Braibant-Giacomelli, Sylvie; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Chhibra, Simranjit Singh; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Montanari, Alessandro; Navarria, Francesco; Perrotta, Andrea; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Albergo, Sebastiano; Costa, Salvatore; Di Mattia, Alessandro; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Chatterjee, Kalyanmoy; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Russo, Lorenzo; Sguazzoni, Giacomo; Strom, Derek; Viliani, Lorenzo; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Primavera, Federica; Calvelli, Valerio; Ferro, Fabrizio; Ravera, Fabio; Robutti, Enrico; Tosi, Silvano; Benaglia, Andrea; Beschi, Andrea; Brianza, Luca; Brivio, Francesco; Ciriolo, Vincenzo; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Ghezzi, Alessio; Govoni, Pietro; Malberti, Martina; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pauwels, Kristof; Pedrini, Daniele; Pigazzini, Simone; Ragazzi, Stefano; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; Di Guida, Salvatore; Fabozzi, Francesco; Fienga, Francesco; Iorio, Alberto Orso Maria; Khan, Wajid Ali; Lista, Luca; Meola, Sabino; Paolucci, Pierluigi; Sciacca, Crisostomo; Thyssen, Filip; Azzi, Patrizia; Bacchetta, Nicola; Benato, Lisa; Bisello, Dario; Boletti, Alessio; Carlin, Roberto; Carvalho Antunes De Oliveira, Alexandra; Checchia, Paolo; De Castro Manzano, Pablo; Dorigo, Tommaso; Dosselli, Umberto; Gasparini, Fabrizio; Gasparini, Ugo; Gozzelino, Andrea; Lacaprara, Stefano; Margoni, Martino; Meneguzzo, Anna Teresa; Pozzobon, Nicola; Ronchese, Paolo; Rossin, Roberto; Simonetto, Franco; Torassa, Ezio; Zanetti, Marco; Zotto, Pierluigi; Zumerle, Gianni; Braghieri, Alessandro; Magnani, Alice; Montagna, Paolo; Ratti, Sergio P; Re, Valerio; Ressegotti, Martina; Riccardi, Cristina; Salvini, Paola; Vai, Ilaria; Vitulo, Paolo; Alunni Solestizi, Luisa; Biasini, Maurizio; Bilei, Gian Mario; Cecchi, Claudia; Ciangottini, Diego; Fanò, Livio; Leonardi, Roberto; Manoni, Elisa; Mantovani, Giancarlo; Mariani, Valentina; Menichelli, Mauro; Rossi, Alessandro; Santocchia, Attilio; Spiga, Daniele; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Boccali, Tommaso; Borrello, Laura; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Fedi, Giacomo; Giannini, Leonardo; Giassi, Alessandro; Grippo, Maria Teresa; Ligabue, Franco; Lomtadze, Teimuraz; Manca, Elisabetta; Mandorli, Giulio; Messineo, Alberto; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Spagnolo, Paolo; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Barone, Luciano; Cavallari, Francesca; Cipriani, Marco; Daci, Nadir; Del Re, Daniele; Di Marco, Emanuele; Diemoz, Marcella; Gelli, Simone; Longo, Egidio; Margaroli, Fabrizio; Marzocchi, Badder; Meridiani, Paolo; Organtini, Giovanni; Paramatti, Riccardo; Preiato, Federico; Rahatlou, Shahram; Rovelli, Chiara; Santanastasio, Francesco; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bartosik, Nazar; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Cenna, Francesca; Costa, Marco; Covarelli, Roberto; Degano, Alessandro; Demaria, Natale; Kiani, Bilal; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Monteil, Ennio; Monteno, Marco; Obertino, Maria Margherita; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Pinna Angioni, Gian Luca; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Shchelina, Ksenia; Sola, Valentina; Solano, Ada; Staiano, Amedeo; Traczyk, Piotr; Belforte, Stefano; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Zanetti, Anna; Kim, Dong Hee; Kim, Gui Nyun; Kim, Min Suk; Lee, Jeongeun; Lee, Sangeun; Lee, Seh Wook; Moon, Chang-Seong; Oh, Young Do; Sekmen, Sezen; Son, Dong-Chul; Yang, Yu Chul; Lee, Ari; Kim, Hyunchul; Moon, Dong Ho; Oh, Geonhee; Brochero Cifuentes, Javier Andres; Goh, Junghwan; Kim, Tae Jeong; Cho, Sungwoong; Choi, Suyong; Go, Yeonju; Gyun, Dooyeon; Ha, Seungkyu; Hong, Byung-Sik; Jo, Youngkwon; Kim, Yongsun; Lee, Kisoo; Lee, Kyong Sei; Lee, Songkyo; Lim, Jaehoon; Park, Sung Keun; Roh, Youn; Almond, John; Kim, Junho; Kim, Jae Sung; Lee, Haneol; Lee, Kyeongpil; Nam, Kyungwook; Oh, Sung Bin; Radburn-Smith, Benjamin Charles; Seo, Seon-hee; Yang, Unki; Yoo, Hwi Dong; Yu, Geum Bong; Kim, Hyunyong; Kim, Ji Hyun; Lee, Jason Sang Hun; Park, Inkyu; Choi, Young-Il; Hwang, Chanwook; Lee, Jongseok; Yu, Intae; Dudenas, Vytautas; Juodagalvis, Andrius; Vaitkus, Juozas; Ahmed, Ijaz; Ibrahim, Zainol Abidin; Md Ali, Mohd Adli Bin; Mohamad Idris, Faridah; Wan Abdullah, Wan Ahmad Tajuddin; Yusli, Mohd Nizam; Zolkapli, Zukhaimira; Reyes-Almanza, Rogelio; Ramirez-Sanchez, Gabriel; Duran-Osuna, Cecilia; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-De La Cruz, Ivan; Rabadán-Trejo, Raúl Iraq; Lopez-Fernandez, Ricardo; Mejia Guisao, Jhovanny; Sánchez Hernández, Alberto; Carrillo Moreno, Salvador; Oropeza Barrera, Cristina; Vazquez Valencia, Fabiola; Eysermans, Jan; Pedraza, Isabel; Salazar Ibarguen, Humberto Antonio; Uribe Estrada, Cecilia; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Ahmad, Ashfaq; Ahmad, Muhammad; Hassan, Qamar; Hoorani, Hafeez R; Saddique, Asif; Shah, Mehar Ali; Shoaib, Muhammad; Waqas, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bozena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Szleper, Michal; Zalewski, Piotr; Bunkowski, Karol; Byszuk, Adrian; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Olszewski, Michal; Pyskir, Andrzej; Walczak, Marek; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Di Francesco, Agostino; Faccioli, Pietro; Galinhas, Bruno; Gallinaro, Michele; Hollar, Jonathan; Leonardo, Nuno; Lloret Iglesias, Lara; Nemallapudi, Mythra Varun; Seixas, Joao; Strong, Giles; Toldaiev, Oleksii; Vadruccio, Daniele; Varela, Joao; Afanasiev, Serguei; Bunin, Pavel; Gavrilenko, Mikhail; Golutvin, Igor; Gorbunov, Ilya; Kamenev, Alexey; Karjavin, Vladimir; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Palichik, Vladimir; Perelygin, Victor; Shmatov, Sergey; Shulha, Siarhei; Skatchkov, Nikolai; Smirnov, Vitaly; Voytishin, Nikolay; Zarubin, Anatoli; Ivanov, Yury; Kim, Victor; Kuznetsova, Ekaterina; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sosnov, Dmitry; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Karneyeu, Anton; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Pozdnyakov, Ivan; Safronov, Grigory; Spiridonov, Alexander; Stepennov, Anton; Toms, Maria; Vlasov, Evgueni; Zhokin, Alexander; Aushev, Tagir; Bylinkin, Alexander; Chistov, Ruslan; Danilov, Mikhail; Parygin, Pavel; Philippov, Dmitry; Polikarpov, Sergey; Tarkovskii, Evgenii; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Terkulov, Adel; Baskakov, Alexey; Belyaev, Andrey; Boos, Edouard; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Kodolova, Olga; Korotkikh, Vladimir; Lokhtin, Igor; Miagkov, Igor; Obraztsov, Stepan; Petrushanko, Sergey; Savrin, Viktor; Snigirev, Alexander; Vardanyan, Irina; Blinov, Vladimir; Skovpen, Yuri; Shtol, Dmitry; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Elumakhov, Dmitry; Godizov, Anton; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Mandrik, Petr; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Cirkovic, Predrag; Devetak, Damir; Dordevic, Milos; Milosevic, Jovan; Rekovic, Vladimir; Alcaraz Maestre, Juan; Bachiller, Irene; Barrio Luna, Mar; Cerrada, Marcos; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Flix, Jose; Fouz, Maria Cruz; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Moran, Dermot; Pérez-Calero Yzquierdo, Antonio María; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Senghi Soares, Mara; Álvarez Fernández, Adrian; Albajar, Carmen; de Trocóniz, Jorge F; Missiroli, Marino; Cuevas, Javier; Erice, Carlos; Fernandez Menendez, Javier; Gonzalez Caballero, Isidro; González Fernández, Juan Rodrigo; Palencia Cortezon, Enrique; Sanchez Cruz, Sergio; Vischia, Pietro; Vizan Garcia, Jesus Manuel; Cabrillo, Iban Jose; Calderon, Alicia; Chazin Quero, Barbara; Curras, Esteban; Duarte Campderros, Jordi; Fernandez, Marcos; Garcia-Ferrero, Juan; Gomez, Gervasio; Lopez Virto, Amparo; Marco, Jesus; Martinez Rivero, Celso; Martinez Ruiz del Arbol, Pablo; Matorras, Francisco; Piedra Gomez, Jonatan; Rodrigo, Teresa; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Trevisani, Nicolò; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Akgun, Bora; Auffray, Etiennette; Baillon, Paul; Ball, Austin; Barney, David; Bendavid, Joshua; Bianco, Michele; Bloch, Philippe; Bocci, Andrea; Botta, Cristina; Camporesi, Tiziano; Castello, Roberto; Cepeda, Maria; Cerminara, Gianluca; Chapon, Emilien; Chen, Yi; D'Enterria, David; Dabrowski, Anne; Daponte, Vincenzo; David Tinoco Mendes, Andre; De Gruttola, Michele; De Roeck, Albert; Deelen, Nikkie; Dobson, Marc; Du Pree, Tristan; Dünser, Marc; Dupont, Niels; Elliott-Peisert, Anna; Everaerts, Pieter; Fallavollita, Francesco; Franzoni, Giovanni; Fulcher, Jonathan; Funk, Wolfgang; Gigi, Dominique; Gilbert, Andrew; Gill, Karl; Glege, Frank; Gulhan, Doga; Harris, Philip; Hegeman, Jeroen; Innocente, Vincenzo; Jafari, Abideh; Janot, Patrick; Karacheban, Olena; Kieseler, Jan; Knünz, Valentin; Kornmayer, Andreas; Kortelainen, Matti J; 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Bouvier, Elvire; Burt, Kira; Clare, Robert; Ellison, John Anthony; Gary, J William; Ghiasi Shirazi, Seyyed Mohammad Amin; Hanson, Gail; Heilman, Jesse; Karapostoli, Georgia; Kennedy, Elizabeth; Lacroix, Florent; Long, Owen Rosser; Olmedo Negrete, Manuel; Paneva, Mirena Ivova; Si, Weinan; Wang, Long; Wei, Hua; Wimpenny, Stephen; Yates, Brent; Branson, James G; Cittolin, Sergio; Derdzinski, Mark; Gerosa, Raffaele; Gilbert, Dylan; Hashemi, Bobak; Holzner, André; Klein, Daniel; Kole, Gouranga; Krutelyov, Vyacheslav; Letts, James; Masciovecchio, Mario; Olivito, Dominick; Padhi, Sanjay; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Tadel, Matevz; Vartak, Adish; Wasserbaech, Steven; Wood, John; Würthwein, Frank; Yagil, Avraham; Zevi Della Porta, Giovanni; Amin, Nick; Bhandari, Rohan; Bradmiller-Feld, John; Campagnari, Claudio; Dishaw, Adam; Dutta, Valentina; Franco Sevilla, Manuel; Gouskos, Loukas; Heller, Ryan; Incandela, Joe; Ovcharova, Ana; Qu, Huilin; Richman, Jeffrey; Stuart, David; Suarez, Indara; Yoo, Jaehyeok; Anderson, Dustin; Bornheim, Adolf; Lawhorn, Jay Mathew; Newman, Harvey B; Nguyen, Thong; Pena, Cristian; Spiropulu, Maria; Vlimant, Jean-Roch; Xie, Si; Zhang, Zhicai; Zhu, Ren-Yuan; Andrews, Michael Benjamin; Ferguson, Thomas; Mudholkar, Tanmay; Paulini, Manfred; Russ, James; Sun, Menglei; Vogel, Helmut; Vorobiev, Igor; Weinberg, Marc; Cumalat, John Perry; Ford, William T; Jensen, Frank; Johnson, Andrew; Krohn, Michael; Leontsinis, Stefanos; Mulholland, Troy; Stenson, Kevin; Wagner, Stephen Robert; Alexander, James; Chaves, Jorge; Chu, Jennifer; Dittmer, Susan; Mcdermott, Kevin; Mirman, Nathan; Patterson, Juliet Ritchie; Quach, Dan; Rinkevicius, Aurelijus; Ryd, Anders; Skinnari, Louise; Soffi, Livia; Tan, Shao Min; Tao, Zhengcheng; Thom, Julia; Tucker, Jordan; Wittich, Peter; Zientek, Margaret; Abdullin, Salavat; Albrow, Michael; Alyari, Maral; Apollinari, Giorgio; Apresyan, Artur; Apyan, Aram; Banerjee, Sunanda; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; 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Taylor, Devin; Woods, Nathaniel

    2017-01-01

    The first observation of top quark production in proton-nucleus collisions is reported using proton-lead data collected by the CMS experiment at the CERN LHC at a nucleon-nucleon center-of-mass energy of $\\sqrt{\\smash[b]{s_{\\mathrm{NN}}}} = $ 8.16 TeV. The measurement is performed using events with exactly one isolated electron or muon and at least four jets. The data sample corresponds to an integrated luminosity of 174 nb$^{-1}$. The significance of the $\\mathrm{t\\bar{t}}$ signal against the background-only hypothesis is above five standard deviations. The measured cross section is $\\sigma_{\\mathrm{t\\bar{t}}} = $ 45 $\\pm$ 8 nb, consistent with predictions from perturbative quantum chromodynamics.

  20. Reward and reinforcement activity in the nucleus accumbens during learning

    Directory of Open Access Journals (Sweden)

    John Thomas Gale

    2014-04-01

    Full Text Available The nucleus accumbens core (NAcc has been implicated in learning associations between sensory cues and profitable motor responses. However, the precise mechanisms that underlie these functions remain unclear. We recorded single-neuron activity from the NAcc of primates trained to perform a visual-motor associative learning task. During learning, we found two distinct classes of NAcc neurons. The first class demonstrated progressive increases in firing rates at the go-cue, feedback/tone and reward epochs of the task, as novel associations were learned. This suggests that these neurons may play a role in the exploitation of rewarding behaviors. In contrast, the second class exhibited attenuated firing rates, but only at the reward epoch of the task. These findings suggest that some NAcc neurons play a role in reward-based reinforcement during learning.

  1. The dolphin cochlear nucleus: topography, histology and functional implications.

    Science.gov (United States)

    Malkemper, E P; Oelschläger, H H A; Huggenberger, S

    2012-02-01

    Despite the outstanding auditory capabilities of dolphins, there is only limited information available on the cytology of the auditory brain stem nuclei in these animals. Here, we investigated the cochlear nuclei (CN) of five brains of common dolphins (Delphinus delphis) and La Plata dolphins (Pontoporia blainvillei) using cell and fiber stain microslide series representing the three main anatomical planes. In general, the CN in dolphins comprise the same set of subnuclei as in other mammals. However, the volume ratio of the dorsal cochlear nucleus (DCN) in relation to the ventral cochlear nucleus (VCN) of dolphins represents a minimum among the mammals examined so far. Because, for example, in cats the DCN is necessary for reflexive orientation of the head and pinnae towards a sound source, the massive restrictions in head movability in dolphins and the absence of outer ears may be correlated with the reduction of the DCN. Moreover, the same set of main neuron types were found in the dolphin CN as in other mammals, including octopus and multipolar cells. Because the latter two types of neurons are thought to be involved in the recognition of complex sounds, including speech, we suggest that, in dolphins, they may be involved in the processing of their communication signals. Comparison of the toothed whale species studied here revealed that large spherical cells were present in the La Plata dolphin but absent in the common dolphin. These neurons are known to be engaged in the processing of low-frequency sounds in terrestrial mammals. Accordingly, in the common dolphin, the absence of large spherical cells seems to be correlated with a shift of its auditory spectrum into the high-frequency range above 20 kHz. The existence of large spherical cells in the VCN of the La Plata dolphin, however, is enigmatic asthis species uses frequencies around 130 kHz.

  2. A universal description of pseudorapidity distributions in both nucleus-nucleus and p-p collisions at now available energy regions

    CERN Document Server

    Jiang, Z J; Huang, Y

    2016-01-01

    Investigations have shown that the collective motion not only appears in nucleus-nucleus but also in p-p collisions. The best tool for depicting such collective motion is relativistic hydrodynamics. In this paper, the collective motion is assumed obeying the hydro model which integrates the features of Landau and Hwa-Bjorken theory and is one of a very few analytically solvable models. The fluid is then supposed freezing out into charged particles from a time-like hypersurface with a fixed time of t_FO . The researches of present paper show that this part of charged particles together with leading particles, which, by conventional definition, carry on the quantum numbers of colliding nucleons and take away the most part of incident energy, can give a proper universal description to the pseudorapidity distributions of charged particles measured in both nucleus-nucleus and p-p collisions at now available energy regions.

  3. GABAergic projections to the oculomotor nucleus in the goldfish (Carassius auratus

    Directory of Open Access Journals (Sweden)

    M. Angeles eLuque

    2011-02-01

    Full Text Available The mammalian oculomotor nucleus receives a strong -aminobutyric acid (GABAergic synaptic input, whereas such projections have rarely been reported in fish. In order to determine whether this synaptic organization is preserved across vertebrates, we investigated the GABAergic projections to the oculomotor nucleus in the goldfish by combining retrograde transport of biotin dextran amine, injected into the antidromically identified oculomotor nucleus, and GABA immunohistochemistry. The main source of GABAergic afferents to the oculomotor nucleus was the ipsilateral anterior octaval nucleus, with only a few, if any, GABAergic neurons being located in the contralateral tangential and descending nuclei of the octaval column. In mammals there is a nearly exclusive ipsilateral projection from vestibular neurons to the oculomotor nucleus via GABAergic inhibitory inputs; thus, the vestibulooculomotor GABAergic circuitry follows a plan that appears to be shared throughout the vertebrate phylogeny. The second major source of GABAergic projections was the rhombencephalic reticular formation, primarily from the medial area but, to a lesser extent, from the inferior area. A few GABAergic oculomotor projecting neurons were also observed in the ipsilateral nucleus of the medial longitudinal fasciculus. The GABAergic projections from neurons located in both the reticular formation surrounding the abducens nucleus and the nucleus of the medial reticular formation have primarily been related to the control of saccadic eye movements. Finally, all retrogradely labeled internuclear neurons of the abducens nucleus, and neurons in the cerebellum (close to the caudal lobe, were negative for GABA. These data suggest that the vestibuloocular and saccadic inhibitory GABAergic systems appear early in vertebrate phylogeny to modulate the firing properties of the oculomotor nucleus motoneurons.

  4. Multiplicity distribution of final-state particles and different contributions of related Sources in nucleus-nucleus collisions at high energies

    Institute of Scientific and Technical Information of China (English)

    SUN Zhu; LIU Pu-Hu

    2008-01-01

    The final state particle multiplicity distributions in high-energy nucleus-nucleus collisions are described by two different sub-distributious contributed by a single nucleon.The Monte Carlo calculated results from the two sub-distributions and the participant-spectator model are compared and found to be in agreement with the experimental data of Au-Au collisions ats=130 AGeV and Pb-Pb collisions at 158 AGeV.

  5. NPY and VGF Immunoreactivity Increased in the Arcuate Nucleus, but Decreased in the Nucleus of the Tractus Solitarius, of Type-II Diabetic Patients

    Science.gov (United States)

    Saderi, Nadia; Salgado-Delgado, Roberto; Avendaño-Pradel, Rafael; Basualdo, Maria del Carmen; Ferri, Gian-Luca; Chávez-Macías, Laura; Escobar, Carolina; Buijs, Ruud M.

    2012-01-01

    Ample animal studies demonstrate that neuropeptides NPY and α-MSH expressed in Arcuate Nucleus and Nucleus of the Tractus Solitarius, modulate glucose homeostasis and food intake. In contrast is the absence of data validating these observations for human disease. Here we compare the post mortem immunoreactivity of the metabolic neuropeptides NPY, αMSH and VGF in the infundibular nucleus, and brainstem of 11 type-2 diabetic and 11 non-diabetic individuals. α-MSH, NPY and tyrosine hydroxylase in human brain are localized in the same areas as in rodent brain. The similar distribution of NPY, α-MSH and VGF indicated that these neurons in the human brain may share similar functionality as in the rodent brain. The number of NPY and VGF immuno positive cells was increased in the infundibular nucleus of diabetic subjects in comparison to non-diabetic controls. In contrast, NPY and VGF were down regulated in the Nucleus of the Tractus Solitarius of diabetic patients. These results suggest an activation of NPY producing neurons in the arcuate nucleus, which, according to animal experimental studies, is related to a catabolic state and might be the basis for increased hepatic glucose production in type-2 diabetes. PMID:22808091

  6. NPY and VGF immunoreactivity increased in the arcuate nucleus, but decreased in the nucleus of the Tractus Solitarius, of type-II diabetic patients.

    Science.gov (United States)

    Saderi, Nadia; Salgado-Delgado, Roberto; Avendaño-Pradel, Rafael; Basualdo, Maria del Carmen; Ferri, Gian-Luca; Chávez-Macías, Laura; Roblera, Juan E Olvera; Escobar, Carolina; Buijs, Ruud M

    2012-01-01

    Ample animal studies demonstrate that neuropeptides NPY and α-MSH expressed in Arcuate Nucleus and Nucleus of the Tractus Solitarius, modulate glucose homeostasis and food intake. In contrast is the absence of data validating these observations for human disease. Here we compare the post mortem immunoreactivity of the metabolic neuropeptides NPY, αMSH and VGF in the infundibular nucleus, and brainstem of 11 type-2 diabetic and 11 non-diabetic individuals. α-MSH, NPY and tyrosine hydroxylase in human brain are localized in the same areas as in rodent brain. The similar distribution of NPY, α-MSH and VGF indicated that these neurons in the human brain may share similar functionality as in the rodent brain. The number of NPY and VGF immuno positive cells was increased in the infundibular nucleus of diabetic subjects in comparison to non-diabetic controls. In contrast, NPY and VGF were down regulated in the Nucleus of the Tractus Solitarius of diabetic patients. These results suggest an activation of NPY producing neurons in the arcuate nucleus, which, according to animal experimental studies, is related to a catabolic state and might be the basis for increased hepatic glucose production in type-2 diabetes.

  7. NPY and VGF immunoreactivity increased in the arcuate nucleus, but decreased in the nucleus of the Tractus Solitarius, of type-II diabetic patients.

    Directory of Open Access Journals (Sweden)

    Nadia Saderi

    Full Text Available Ample animal studies demonstrate that neuropeptides NPY and α-MSH expressed in Arcuate Nucleus and Nucleus of the Tractus Solitarius, modulate glucose homeostasis and food intake. In contrast is the absence of data validating these observations for human disease. Here we compare the post mortem immunoreactivity of the metabolic neuropeptides NPY, αMSH and VGF in the infundibular nucleus, and brainstem of 11 type-2 diabetic and 11 non-diabetic individuals. α-MSH, NPY and tyrosine hydroxylase in human brain are localized in the same areas as in rodent brain. The similar distribution of NPY, α-MSH and VGF indicated that these neurons in the human brain may share similar functionality as in the rodent brain. The number of NPY and VGF immuno positive cells was increased in the infundibular nucleus of diabetic subjects in comparison to non-diabetic controls. In contrast, NPY and VGF were down regulated in the Nucleus of the Tractus Solitarius of diabetic patients. These results suggest an activation of NPY producing neurons in the arcuate nucleus, which, according to animal experimental studies, is related to a catabolic state and might be the basis for increased hepatic glucose production in type-2 diabetes.

  8. Antiproton Production in 11.5A GeV/c Au+Pb Nucleus-Nucleus Collisions

    Energy Technology Data Exchange (ETDEWEB)

    De Cataldo, G.; Giglietto, N.; Raino, A.; Spinelli, P. [University of Bari/INFN, Bari (Italy); Dover, C.B. [Brookhaven National Laboratory, Upton, New York 11973 (United States); Huang, H.Z. [University of California at Los Angeles, Los Angeles, California 90024 (United States); Hill, J.C.; Libby, B.; Wohn, F.K. [Iowa State University, Ames, Iowa 50011 (United States); Rabin, M.S. [University of Massachusetts, Amherst, Massachusetts 01003 (United States); Haridas, P.; Pless, I.A.; Van Buren, G. [Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Armstrong, T.A.; Lewis, R.A.; Reid, J.D.; Smith, G.A.; Toothacker, W.S. [Pennsylvania State University, University Park, Pennsylvania 16802 (United States); Davies, R.; Hirsch, A.S.; Porile, N.T.; Rimai, A.; Scharenberg, R.P.; Srivastava, B.K.; Tincknell, M.L. [Purdue University, West Lafayette, Indiana 47907 (United States); Greene, S.V. [Vanderbilt University, Nashville, Tennessee 37235 (United States); Bennett, S.J.; Cormier, T.M.; Dee, P.; Fachini, P.; Kim, B.; Li, Q.; Li, Y.; Munhoz, M.G.; Pruneau, C.A.; Wilson, W.K.; Zhao, K. [Wayne State University, Detroit, Michigan 48201 (United States); Barish, K.N.; Bennett, M.J.; Chikanian, A.; Coe, S.D.; Diebold, G.E.; Finch, L.E.; George, N.K.; Kumar, B.S.; Lajoie, J.G.; Majka, R.D.; Nagle, J.L.; Pope, J.K.; Rotondo, F.S.; Sandweiss, J.; Slaughter, A.J.; Wolin, E.J. [Yale University, New Haven, Connecticut 06520 (United States)

    1997-11-01

    We present the first results from the E864 Collaboration on the production of antiprotons in 10{percent} central 11.5A GeV /c Au+Pb nucleus collisions at the Brookhaven Alternating Gradient Synchrotron. We report invariant multiplicities for antiproton production in the kinematic region 1.4{lt}y{lt}2.2 and 50{lt} p{sub T}{lt} 300 MeV/c , and compare our data with a first collision scaling model and previously published results from the E878 Collaboration. The differences between the E864 and E878 antiproton measurements and the implications for antihyperon production are discussed. {copyright} {ital 1997} {ital The American Physical Society}

  9. Functional interactions between the nucleus tractus solitarius (NTS) and nucleus accumbens shell in modulating memory for arousing experiences.

    Science.gov (United States)

    Kerfoot, Erin C; Chattillion, Elizabeth A; Williams, Cedric L

    2008-01-01

    The shell division of the nucleus accumbens receives noradrenergic input from neurons in the nucleus of the solitary tract (NTS) that transmit information regarding fluctuations in peripheral hormonal and autonomic activity. Accumbens shell neurons also receive converging inputs from limbic areas such as the hippocampus and amygdala that process newly acquired information. However, few studies have explored whether peripheral information regarding changes in emotional arousal contributes to memory processing in the accumbens. The beneficial effects on memory produced by emotional arousal and the corresponding activation of NTS neurons may be mediated through influences on neuronal activity in the accumbens shell during memory encoding. To explore this putative relationship, Experiment 1 examined interactions between the NTS and the accumbens shell in modulating memory for responses acquired after footshock training in a water-motivated inhibitory avoidance task. Memory for the noxious shock was significantly improved by posttraining excitation of noradrenergic NTS neurons. The enhanced retention produced by activating NTS neurons was attenuated by suppressing neuronal activity in the accumbens shell with bupivacaine (0.25%/0.5 microl). Experiment 2 examined the direct involvement of accumbens shell noradrenergic activation in the modulation of memory for psychologically arousing events such as a reduction in perceived reward value. Noradrenergic activation of the accumbens shell with phenylephrine (1.0 microg/0.5 microl) produced an enhancement in memory for the frustrating experience relative to control injections as evidenced by runway performance on an extended seven-day retention test. These findings demonstrate a functional relationship between NTS neurons and the accumbens shell in modulating memory following physiological arousal and identifies a role of norepinephrine in modulating synaptic activity in the accumbens shell to facilitate this process.

  10. Characteristics of rostral solitary tract nucleus neurons with identified afferent connections that project to the parabrachial nucleus in rats.

    Science.gov (United States)

    Suwabe, Takeshi; Bradley, Robert M

    2009-07-01

    Afferent information derived from oral chemoreceptors is transmitted to second-order neurons in the rostral solitary tract nucleus (rNST) and then relayed to other CNS locations responsible for complex sensory and motor behaviors. Here we investigate the characteristics of rNST neurons sending information rostrally to the parabrachial nucleus (PBN). Afferent connections to these rNST-PBN projection neurons were identified by anterograde labeling of the chorda tympani (CT), glossopharyngeal (IX), and lingual (LV) nerves. We used voltage- and current-clamp recordings in brain slices to characterize the expression of both the transient A-type potassium current, IKA and the hyperpolarization-activated inward current, Ih, important determinants of neuronal repetitive discharge characteristics. The majority of rNST-PBN neurons express IKA, and these IKA-expressing neurons predominate in CT and IX terminal fields but were expressed in approximately half of the neurons in the LV field. rNST-PBN neurons expressing Ih were evenly distributed among CT, IX and LV terminal fields. However, expression patterns of IKA and Ih differed among CT, IX, and LV fields. IKA-expressing neurons frequently coexpress Ih in CT and IX terminal fields, whereas neurons in LV terminal field often express only Ih. After GABAA receptor block all rNST-PBN neurons responded to afferent stimulation with all-or-none excitatory synaptic responses. rNST-PBN neurons had either multipolar or elongate morphologies and were distributed throughout the rNST, but multipolar neurons were more often encountered in CT and IX terminal fields. No correlation was found between the biophysical and morphological characteristics of the rNST-PBN projection neurons in each terminal field.

  11. Spatial and dynamic organization of molecular structures in the cell nucleus

    NARCIS (Netherlands)

    Brouwer, Anne-Kee

    2010-01-01

    In this thesis we attempt to provide a better understanding of the principles that underlie the spatial dynamic organization of the cell nucleus. Chapter 1 reviews the current status of knowledge about the structural and functional organization of the cell nucleus. In chapter 2, the development of a

  12. Whisker movements evoked by stimulation of single motor neurons in the facial nucleus of the rat

    NARCIS (Netherlands)

    L.J. Herfst (Lucas); M. Brecht (Michael)

    2008-01-01

    textabstractThe lateral facial nucleus is the sole output structure whose neuronal activity leads to whisker movements. To understand how single facial nucleus neurons contribute to whisker movement we combined single-cell stimulation and high-precision whisker tracking. Half of the 44 stimulated ne

  13. The Stimulatory Effect of Notochordal Cell-Conditioned Medium in a Nucleus Pulposus Explant Culture

    NARCIS (Netherlands)

    de Vries, Stefan A H; van Doeselaar, Marina; Meij, Björn P; Tryfonidou, Marianna A; Ito, K

    2016-01-01

    Objectives: Notochordal cell-conditioned medium (NCCM) has previously shown to have a stimulatory effect on nucleus pulposus cells (NPCs) and bone marrow stromal cells (BMSCs) in alginate and pellet cultures. These culture methods provide a different environment than the nucleus pulposus (NP) tissue

  14. The Stimulatory Effect of Notochordal-Cell Conditioned Medium in a Nucleus Pulposus Explant Culture

    NARCIS (Netherlands)

    de Vries, Stefan; Doeselaar, Marina van; Meij, Björn; Tryfonidou, M; Ito, Keita

    2015-01-01

    OBJECTIVES: Notochordal cell-conditioned medium (NCCM) has previously shown to have a stimulatory effect on nucleus pulposus cells (NPCs) and bone marrow stromal cells (BMSCs) in alginate and pellet cultures. These culture methods provide a different environment than the nucleus pulposus (NP) tissue

  15. Subthalamic nucleus stimulation influences expression and suppression of impulsive behavior in Parkinson's disease

    NARCIS (Netherlands)

    Wylie, S.A.; Ridderinkhof, K.R.; Elias, W.J.; Frysinger, R.C.; Bashore, T.R.; Downs, K.E.; van Wouwe, N.C.; van den Wildenberg, W.P.M.

    2010-01-01

    Past studies show beneficial as well as detrimental effects of subthalamic nucleus deep-brain stimulation on impulsive behaviour. We address this paradox by investigating individuals with Parkinson’s disease treated with subthalamic nucleus stimulation (n = 17) and healthy controls without Parkinson

  16. Phylogeny of nucleus medianus of the posterior tubercle in rayfinned fishes.

    Science.gov (United States)

    Northcutt, R Glenn

    2009-03-01

    The brains of ray-finned fishes form a morphocline of increasing complexity, from cladistians through teleosts. This is particularly apparent in the posterior tubercle of the diencephalon. In cladistians, the posterior tubercle consists of a periventricular nucleus and a migrated nucleus medianus that is fused across the midline. In more advanced ray-finned fishes, such as gars and bowfins, the posterior tubercle comprises numerous additional migrated nuclei, termed the preglomerular complex, in addition to a more well developed nucleus medianus. In teleosts, the most derived ray-finned fishes, there is an even more elaborate preglomerular complex, but there is no recognizable nucleus medianus. In an attempt to explain the variation in the posterior tubercle of the diencephalon in ray-finned fishes, the immunohistochemistry and connections of nucleus medianus were examined in cladistians, gars and bowfins. In each of these taxa, nucleus medianus exhibits large numbers of calretinin-positive neurons and has ascending projections that terminate in several divisions of the pallium. Although teleosts, such as goldfish, also exhibit numerous cell groups in the posterior tubercle that are rich in calretinin, none of these cell groups has connections that are comparable to those of nucleus medianus in non-teleost ray-finned fishes. It is possible, therefore, that nucleus medianus was lost with the origin of teleosts.

  17. A stereological study of the mediodorsal thalamic nucleus in Down syndrome

    DEFF Research Database (Denmark)

    Karlsen, A S; Korbo, S; Uylings, H B M

    2014-01-01

    The total number of neurons and glial cells in the mediodorsal thalamic (MDT) nucleus of four aged females with Down syndrome (DS; mean age 69years) was estimated and compared to six age- and sex-matched controls. The MDT nucleus was delineated on coronal sections, and cell numbers (large and small...

  18. Shape study of the N=Z waiting-point nucleus 72Kr via beta decay

    CERN Document Server

    Briz Monago, Jose Antonio; Nácher González, Enrique

    The Ph.D. thesis entitled “Shape study of the N=Z waiting-point nucleus 72Kr via beta decay” is devoted to the study of the shape of the ground state of the 72Kr nucleus. It is an N=Z nucleus in the mass region A~70-80 where shape transitions and the shape coexistence phenomena have been identified. Furthermore, this nucleus participates in the rp-process as a waiting point due to the slowdown of the process taking place at the arrival to this nucleus. The study of the properties of this nucleus is interesting from the Nuclear Structure point of view, for the phenomena occurring in its mass region and have been predicted for it, and from the Nuclear Astrophysics for the accurate performance of astrophysical calculations. The β+/EC decay of the 72Kr nucleus has been studied through two complementary experiments at the ISOLDE facility at CERN in Geneva (Switzerland). In one of them, the low-spin structure of the daughter nucleus, 72Br, has been revised via conversion electron spectroscopy where the convers...

  19. Evidence for a periaqueductal gray-nucleus retroambiguus spinal cord pathway in the rat

    NARCIS (Netherlands)

    Holstege, G.; Kerstens, Lenka; Moes, M.C.; Horst, V.G.J.M. van der

    1997-01-01

    The nucleus retroambiguus in the cat has been shown to receive strong projections from the periaqueductal gray and to send fibres to distinct motoneuronal cell groups in brainstem and spinal cord. The nucleus retroambiguus plays a role in the production of vocalization and possibly copulatory

  20. Formation of the dumbbell-like nucleus of a comet by sublimation

    Science.gov (United States)

    Vavilov, Dmitrii; Medvedev, Yurii; Zatitskiy, Pavel

    2016-10-01

    The nucleus of the comet 67P/Churyumov-Gerasimenko is an elongated body with a deep groove around the middle. There are also other comets that look like dumbbells (e.g. 103P/Hartley 2, 19P/Borrelly, 1P/Halley). Two most probable interpretations are discussed in the scientific society. The first hypothesis explains the creation of such an object as sticking of two cometesimals during the process of formation. The second one suggests that the sublimation process can change the nucleus shape and make a groove in the middle.In this work we consider the second hypothesis. It was assumed that the spin axis of the nucleus is perpendicular to the plane of the cometary orbit and that initially the nucleus shape is a sphere. Thus, the problem is represented as a differential equation, which describes the change of the cometary nucleus. We solved this equation analytically. It was shown that initially a convex cometary nucleus (e.g. a sphere), consisting of homogeneous material, can not be transformed into a dumbbell-like body by the influence of sublimation. However, assuming that the density in the centre of the nucleus is less than on the surface, a groove can arise on the equator of the cometary nucleus as a result of sublimation.

  1. Spatial and dynamic organization of molecular structures in the cell nucleus

    NARCIS (Netherlands)

    Brouwer, Anne-Kee

    2010-01-01

    In this thesis we attempt to provide a better understanding of the principles that underlie the spatial dynamic organization of the cell nucleus. Chapter 1 reviews the current status of knowledge about the structural and functional organization of the cell nucleus. In chapter 2, the development of a

  2. Strangeness production in light and intermediate size nucleus–nucleus collisions

    National Research Council Canada - National Science Library

    Gorenstein, M.I; Greiner, W; Rustamov, A

    2014-01-01

    ....+ ratio in nucleus-nucleus collisions. In doing so we assumed that different values of K.sup.+/I.sup.+, measured in p + p and Pb + Pb interactions at the same collision energy per nucleon, are driven by the finite size effects only...

  3. Three-Dimensional Organization of Chromosome Territories in the Human Interphase Nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); J. Langowski (Jörg)

    1999-01-01

    textabstractDespite the successful linear sequencing of the human genome its three-dimensional structure is widely unknown. The regulation of genes has been shown to be connected closely to the three-dimensional organization of the genome in the cell nucleus. The nucleus of the cell has for a long t

  4. Role of orexin receptors in the nucleus accumbens in dopamine-dependent turning behaviour of rats.

    NARCIS (Netherlands)

    Kotani, A.; Ikeda, H.; Koshikawa, N.; Cools, A.R.

    2008-01-01

    The role of orexin receptors in the nucleus accumbens shell in rat turning behaviour of rats was studied. Unilateral injection of neither the orexin 1 and 2 receptor agonist orexin A (2 microg) nor the orexin 1 receptor antagonist SB 334867 (20 ng) into the nucleus accumbens shell elicited turning b

  5. Planar multipolar cells in the cochlear nucleus project to medial olivocochlear neurons in mouse.

    Science.gov (United States)

    Darrow, Keith N; Benson, Thane E; Brown, M Christian

    2012-05-01

    Medial olivocochlear (MOC) neurons originate in the superior olivary complex and project to the cochlea, where they act to reduce the effects of noise masking and protect the cochlea from damage. MOC neurons respond to sound via a reflex pathway; however, in this pathway the cochlear nucleus cell type that provides input to MOC neurons is not known. We investigated whether multipolar cells of the ventral cochlear nucleus have projections to MOC neurons by labeling them with injections into the dorsal cochlear nucleus. The projections of one type of labeled multipolar cell, planar neurons, were traced into the ventral nucleus of the trapezoid body, where they were observed terminating on MOC neurons (labeled in some cases by a second cochlear injection of FluoroGold). These terminations formed what appear to be excitatory synapses, i.e., containing small, round vesicles and prominent postsynaptic densities. These data suggest that cochlear nucleus planar multipolar neurons drive the MOC neuron's response to sound.

  6. Realizm i idealizm: struktura problemu (Realism and Idealism: the Structure of the Debate

    Directory of Open Access Journals (Sweden)

    Stanisław Judycki

    2009-06-01

    Full Text Available The aim of the article is to systematize fundamental concepts involved in the philosophical debate on realism and idealism. In the first (historical part distinction between appearance and reality (which has its roots in ancient philosophy is presented as one of the sources of the modern debate on realism and idealism. In this part different interpretations of realism and idealism (Descartes, Leibniz, Berkeley, Kant, Heidegger, Moore, Carnap are also analyzed. The second part is concerned with definitions of four fundamental oppositions: metaphysical idealism and epistemological idealism, metaphysical realism and epistemological realism. The third part discusses different forms of realism (naïve realism, critical realism, scientific realism, transcendental realism and conceptual realism and introduces the concept of antirealism. Fourth part deals with connections between realism and idealism debate and such philosophical standpoints as skepticism, agnosticism and solipsism.

  7. Struktura agrarna a rozwój gospodarczy w pracach Władysława Grabskiego

    OpenAIRE

    1982-01-01

    The article is devoted to analysis of Wł. Grabski's (one of the leading Polish interwar economists) opinions concerning the most favourable agrarian structure. Taking into account the fact that Poland's economy in the interwar period possessed distinct characteristics of economic backwardness, the evaluation of "optimal" — according to Grabski — agrarian structure is performed from the viewpoint of a start to accelerated economic devełopment. In this article the author was t...

  8. POMACI STRUKTURA I SEIZMOTEKTONSKA AKTIVNOST ZAPADNOG VELEBITA: NEKA NOVA OPAŽANJA

    OpenAIRE

    Prelogović, Eduard; Kuk, Vlado; Buljan, Renato

    1998-01-01

    U području sjevernog Velebita stalno je prisutna seizmotektonska aktivnost. U povijesti se više puta spominju potresi intenziteta VII° i IX° MCS. U ovom stoljeću najjači potres dogodio se 1916. godine magnitude 5,8. Ključni tektonski pokreti koji uzrokuju pojavljivanje potresa jesu pomaci Jadranske platforme prema sjeveru i odupiranje Dinarida tim pomacima. Tektonska dinamika strukturnog sklopa ovisi o odnosu stresa i deformacija strukturnih jedinica. Prema podacima terenskog mjerenja u iz...

  9. Svojstva i struktura wolframkarbid-kobalt prevlake deponovane plazma-sprej postupkom

    Directory of Open Access Journals (Sweden)

    Mihailo Rade Mrdak

    2013-10-01

    Full Text Available Cilj istraživanja bio je da se optimizacijom plazma-sprej parametara deponuju WC17Co slojevi optimalnih strukturno-mehaničkih karakteristika. Prah je deponovan plazma-sprej postupkom na atmosferskom pritisku (APS.Pri izboru parametara kao osnovni parametar uzet je protok plazma gasa He. Helijum u odnosu na druge gasove ne reaguje sa prahom, proizvodi gušću plazmu sa manjim toplotnim sadržajem i manje inkorporira okolni vazduh u mlaz plazme, što smanjuje dekarburizaciju praha. U istraživanju su korišćene tri grupe uzoraka dobijene sa tri protoka  plazma gasa od 12, 22 i 32 l/min He.  Prevlaka sa najboljim karakteristikama deponovana je na rukavcu vratila glavnog rotora helikoptera "gazela H42" da bi  se smanjio uticaj ležaja  i vibracija na habanje rukavca do 500°C. Procene WC17Co slojeva prevlake urađene su na osnovu njihovih strukturno-mehaničkih karakteristika. Morfologija površine čestica praha WC17Co ispitana je na SEM-u. Mehaničke karakteristike deponovanih prevlaka ispitane su  u skladu sa standardom TURBOMECA. Procena mehaničkih karakteristika slojeva urađena je ispitivanjem mikrotvrdoće metodom HV0.3 i čvrstoće spoja ispitivanjem na zatezanje. Metalografska procena udela pora u slojevima WC17Co prevlaka (image analiza urađena je tehnikom svetlosne mikroskopije u skladu sa standardom Pratt & Whitney. Istraživanja su pokazala da protok plazma gasa bitno utiče na mehaničke osobine i strukture prevlaka. Uvod Plazma-sprej postupak je zastupljen u mnogim industrijama radi poboljšanja karakteristika komponenti ili produženja njihovog radnog veka. Ovaj postupak našao je široku primenu u vazduhoplovnoj industriji i jedan je od najprimenjenijih postupaka za termičko nanošenje prevlaka. Na resurs prevlaka utiču karakteristike deponovanog materijala, njegov faznih sastav, udeo pora i nestopljenih čestica, koheziona i adheziona čvrstoća. Deponovane prevlake WC17Co termosprej postupcima uvek pokazuju promenu u faznom sastavu u odnosu na sastav polaznog praha, što se ne može izbeći. Promenu faznog sastava u deponovanim karbidnim prevlakama opisao je Saha,G.C. i dr. autori (Saha, et al., 2010, pp. 592-595 koji su objasnili uzrok faznih promena. Ispitivanjem faza nanokristalne prevlake WC17Co deponovane termičkim postupkom HVOF i polikristalne prevlake deponovane plazma-sprej postupkom,  ustanovljeno je da u obe prevlake dolazi do, manje ili više, razgradnje polazne faze WC u fazu W2C i W. Ovo razlaganje je izraženije kod plazme zbog viših temperatura. U strukturi polikristalne prevlake deponovane plazmom, pored faze WC uvek su prisutne i faze W2C,W,W3C i mešoviti karbid ή – Co3W3C (Saha, et al., 2010, pp. 592-595. Zbog inkorporiranja vazduha u mlaz plazme i njegovog uticaja na redukciju ugljenika iz karbida, depozicija praha radi se srednjom snagom napajanja plazma-pištolja i sa helijumom kao plazma gasom. Helijum kao plemeniti gas ima velike prednosti kao plazma gas u odnosu na druge gasove. Eksperimentalna istraživanja karakteristika mlazeva plazmi pokazala su da izoterme blizu izlaza iz anode imaju manji prečnik za plazmu Ar-He u odnosu na Ar-H2. Dužina izotermi je takođe manja kod plazme Ar-He zbog manje specifične entalpije i  većeg viskoziteta u odnosu na Ar-H2. Gušća plazma, kao što je Ar-He, može znatno da smanji inkorporiranje okolnog vazduha u mlaz plazme. Mešanje mlaza plazme sa okolnim vazduhom povećava se sa povećanjem jačine strujnog luka i protokom plazma gasa (Roumilhac, et al., 1988, pp. 105-119, (Roumilhac, Fauchais, 1988, pp. 121-126. Helijum zbog ovih osobina omogućuje deponovanje karbidnih prevlaka sa umanjenim procesom dekarburizacije i sa manjim sadržajem  pora. Osobine prevlaka su u direktnoj vezi sa parametrima depozicije. Prah WC17Co razvijen je za potrebe vazduhoplovne industrije. Prevlake na bazi WC17Co su otporne na habanje, abraziju, eroziju, koroziju i kavitaciju do 500°C (Material Product Data Sheet, 2011. U ovom radu predstavljeni su rezultati eksperimentalnih istraživanja uticaja protoka plazma gasa (He na mehanička svojstva i mikrostrukturu slojeva WC17Co. Glavni cilj je bio da se stara tehnologija cementacije  rukavaca vratila zameni deponovanjem WC17Co prevlake plazma-sprej tehnologijom. Analizirane su mehaničke karakteristike i mikrostrukture prevlaka da bi se odabrala prevlaka najboljih karakteristika. Prevlaka sa najboljim mehaničkim i strukturnim karakteristikama je testirana i homologovana na rukavcu vratila glavnog rotora helikoptera "gazela H42" letnim ispitivanjem u trajanju od 50 časova u VZ „Moma Stanojlović" u Batajnici. Materijali za ispitivanje i uzorci Za izradu prevlaka upotrebljen je prah firme „Sulzer Metco” sa oznakom Metco 73F-NS-1. Za izradu praha korišćena je tehnika suvo  raspršavanje/sinterovanje sa sadržajem od 83 tež.%WC i 17 tež.%Co. Prah koji se koristio u eksperimentu imao je raspon granulacije od 11 µm do 53 µm (Material Product Data Sheet, 2011. Čestice praha su porozne  i sfernog oblika. Osnove na koje su deponovane prevlake za procenu strukture i za ispitivanje mikrotvrdoće izrađene su od čelika Č.4171 (X15Cr13 EN10027 u termički neobrađenom stanju dimenzija 70x20x1,5mm . Osnove za ispitivanje čvrstoće spoja takođe su izrađene od čelika Č.4171(X15Cr13EN10027 u termički neobrađenom stanju dimenzija Ø25x50 mm (Turbojet engine-standard practices manuel TURBOMECA. Mehaničke karakterizacije prevlaka WC17Co urađene su prema standardu TURBOMECA (Turbojet engine-standard practices manuel TURBOMECA. Za merenje mikrotvrdoće i metalografska ispitivanja korišćeni su uzorci dimanzija 70 × 20 x 1,5 mm, dok su za ispitivanje zatezne čvrstoće korišćeni uzorci  Ø25 x 50 mm. Merenja mikrotvrdoća izvršena su korišćenjem Vikers dijamant piramide indenter i 300 grama opterećenje (HV0.3. Merenje je urađeno u pravcu duž lamela, u sredini i na krajevima uzorka. Na tri mesta sprovedeno je pet očitavanja, a rezultati su bili  usrednjeni. Testovi zatezne čvrstoće rađeni su na sobnoj temperaturi na hidrauličnoj opremi sa brzinom od 10 mm/min. Korišćena su dva uzoraka u paru, od kojih je prevlaka deponovana samo na jednom od njih. Za svaku grupu WC17Co prevlaka ispitano je po pet uzoraka, a dobijeni rezultati su usrednjeni. Metalografska procena udela pora (image analiza u slojevima WC17Co prevlaka urađena je tehnikom svetlosne mikroskopije u skladu sa standardom Pratt & Whitney (Turbojet Engine – Standard Practices Manual (PN 582005, 2002, Pratt & Whitney, East Hartford, USA. Morfologija čestica praha urađena je na SEM-u (skening elektronskom mikroskopu. Depozicija praha Proces deponovanja slojeva na metalne osnove urađen je plazma-sprej postupkom na atmosferskom pritisku (APS firme Plasmadyne. Depozicija praha urađena je plazma pištoljem SG-100 koji se sastojao od katode tipa K 1083A -129 , anode tipa A 2083-175 i gas-injektora tipa  GI 1083-113. Kao gas korišćen je argon u kombinaciji sa helijumom i snaga napajanja od 40 KW. Protok plazma gasa helijuma bio je osnovni parameter za deponovanje praha. U eksperimentu su korišćena tri različita protoka helijuma od 12 l/min, 22 l/min i 32 l/min. Slojevi su deponovani na supstratima ukupne debljine od 0,020 do 0,025 mm sa plazma pištoljem brzine 500 mm/s. Rezultati i diskusija Vrednosti mikrotvrdoće i čvrstoće spoja deponovanih slojeva su u direktnoj vezi sa protocima helijuma kao plazma gasa. Svi deponovani slojevi imaju vrednosti mikrotvrdoće u propisanim granicama od 850 do 1300 HV0.3 (Material Product Data Sheet, 2011, (Turbojet engine-standard practices manuel TURBOMECA.  Najravnomerniju raspodelu mikrotvrdoće imali su slojevi deponovani sa protokom plazma gasa od 22 l/min.He. Ti slojevi su imali najmanju razliku  mikrotvrdoće između maksimalnih i minimalnih vrednosti (289 HV0.3. Najveću raspodelu mikrotvrdoće pokazali su slojevi  deponovani sa najvećim protokom plazma gasa od 32 l/min He. Ti slojevi imali su najveću razliku mikrotvrdoće između maksimalnih i minimalnih vrednosti (404 HV0.3. Višu raspodelu mikrotvrdoće imali su i slojevi sa najmanjim protokom plazma gasa od 12 l/min He.  Razlika između maksimalnih i minimalnih vrednosti mikrotvrdoće za te slojeve bila je  373 HV0.3. Zatezna čvrstoća spoja je u direktnoj vezi sa protocima plazma gasa He. Vrednosti zatezne čvrstoće spoja deponovanih slojeva sa protocima plazma gasa od 12 l/min i 22 l/ min He, u propisanim su granicama po standardu ( min. 45 MPa (Turbojet engine-standard practices manuel TURBOMECA. Ti slojevi imali su dobru adhezionu čvrstoću sa supstratom i dobru međulamelarnu kohezionu čvrstoću. Najveću vrednost čvrstoće spoja od 49MPa pokazali su slojevi deponovani sa protokom plazma gasa od 22 l/min He, koji su imali najmanju raspodelu mikrotvrdoće. Ti su slojevi imali najmanji udeo pora. Najmanju vrednost zatezne čvrstoće spoja od 42MPa imali su slojevi deponovani sa najvećim protokom plazma gasa He. Ti su slojevi imali najveću raspodelu mikrotvrdoće i najveći udeo mikropora. Ispitivanja zatezne čvrstoće spoja pokazalo je da je za sve deponovane prevlake mehanizam razaranja bio na interfejsu između substrata i prevlake. Kvantitativna analiza ukupnog sadržaja pora u WC17Co slojevima  pokazala je da su izmerene vrednosti u direktnoj vezi sa protocima plazma gasa He. Na prikazanim mikrofotografijama jasno se uočavaju različiti udeli pora u deponovanim slojevima. Najmanji udeo pora bio je u slojevima WC17Co prevlake deponovane sa protokom plazma gasa od 22 l/ min He. U tim slojevima je ukupan udeo pora bio 1%. U slojevima deponovanim sa protokom plazma gasa od 12 l/min He, ukupan udeo pora je bio 1,3%. Najveći udeo pora je bio u slojevima deponovanim sa protokom plazma gasa od 32 l/min He. U tim slojevima pore su izraženije i grublje sa udelom od 2,5%. U svim slojevima  ukupan udeo pora bio je u propisanim granicama od 0,5 do 3% (Material Product Data Sheet, 2011, (Turbojet engine-standard practices manuel TURBOMECA. Mikrostruktura svih prevlaka je lamelarna. Na mikrofotografijama se vidi da su istopljene čestice praha pravilno razlivene. Slojevi prevlake deponovani su kontinualno bez prisutnih mikro i makropukotina kroz slojeve. U slojevima nisu prisutne neistopljene čestice praha, precipitati i interlamelarne pore. U deponovanim slojevima svih prevlaka jasno se uočavaju ravnomerno distribuirane karbidne faze u žilavoj osnovi kobalta. Na svim mikrofotografijama jasno se uočavaju svetla polja metalnih faza i tamnosiva polja karbidnih faza. U svetlim poljima prisutna je polazna metalna faza Co i metalna faza W koja potiče od delimične razgradnje polaznog kubnog monocarbidea WC (Saha, et al., 2010, pp.592-595. U sivim poljima prisutna je polazna faza kubnog monokarbidea WC i karbidne faze koje su nastale razlaganjem kubnog karbida WC u karbide tipa W2C,W3C i mešoviti karbid ή - Co3W3C (Saha, et al., 2010, pp.592-595, (de Villiers Lovelock, 1998, pp.357–373. Zaključak Plazma-sprej postupkom (APS deponovane su prevlake WC17Co sa  protocima plazma gasa od 12 l/min, 22 l/min i 32 l/ min He. U radu su analizirane mehaničke karakteristike deponovanih slojeva i mikrostrukturne karakteristike na svetlosnom mikroskopu. Morfologija čestica praha ispitana je na (SEM skening elektronskom mikroskopu. Na osnovu izvršenih analiza došlo se do određenih zaključaka. Morfologija čestica praha WC17Co je sfernog oblika i tipična je za čestice praha koje se proizvode tehnikom  suvo  raspršavanje/sinterovanje. Vrednosti mikrotvrdoće i čvrstoće spoja deponovanih slojeva bili su u direktnoj vezi sa protocima helijuma kao plazma gasa. Svi deponovani slojevi imali su vrednosti mikrotvrdoće u propisanim granicama od 850 do 1300 HV0.3. Najravnomerniju raspodelu mikrotvrdoće imali su slojevi deponovani sa protokom plazma gasa od 22 l/min He.  Ti su slojevi imali najmanju razliku  mikrotvrdoće između maksimalnih i minimalnih vrednosti (289 HV0.3. Vrednosti zatezne čvrstoće spoja slojeva deponovanih sa protocima plazma gasa od 12 l/min  i 22 l/ min He  bile su u propisanim granicama po standardu ( min. 45 Mpa. Ti su slojevi imali dobru adhezionu čvrstoću sa supstratom i dobru međulamelarnu kohezionu čvrstoću. Najveću vrednost čvrstoće spoja od 49 MPa pokazali su slojevi deponovani sa protokom plazma gasa He, koji su imali najmanju raspodelu mikrotvrdoće. Ti su slojevi imali najmanji udeo pora. Najmanju vrednost zatezne čvrstoće spoja od 42 MPa imali su slojevi deponovani sa najvećim protokom plazma gasa He. Ti su slojevi imali najveću raspodelu mikrotvrdoće i najveći udeo mikropora. Kvantitativna analiza ukupnog sadržaja pora u WC17Co slojevima  pokazala je da su izmerene vrednosti u direktnoj vezi sa protocima plazma gasa He. Najmanji udeo pora bio je u slojevima WC17Co prevlake deponovane sa protokom plazma gasa od 22 l/min He. U tim slojevima je ukupan udeo porao bio 1%. U slojevima deponovanim sa protokom plazma gasa od 12 l/min He, ukupan udeo pora bio je 1,3%. Najveći udeo pora bio je u slojevima deponovanim sa protokom plazma gasa od 32 l/ min He. U tim slojevima pore su izraženije i grublje sa udelom od 2,5%. U svim slojevima  ukupan udeo pora bio je u propisanim granicama od 0,5 do 3%. Mikrostruktura svih prevlaka je lamelarna. Slojevi prevlake su deponovani kontinualno bez prisutnih mikro i makropukotina kroz slojeve. U slojevima nisu prisutne neistopljene čestice praha, precipitati i interlamelarne pore. U deponovanim slojevima svih prevlaka jasno se uočavaju ravnomerno raspoređene karbidne faze u žilavoj osnovi kobalta. U svetlim poljima prisutna je polazna metalna faza Co i metalna faza W koja potiče od delimične razgradnje polaznog kubnog monokarbidea WC. U sivim poljima prisutna je polazna faza kubnog monokarbidea WC i karbidne faze koje su nastale razlaganjem kubnog karbida WC u karbide tipa W2C,W3C i mešoviti karbid ή – Co3W3C. Dobijeni rezultati su pokazali da protok plazma gasa He bitno utiče na mehaničke karakteristike slojeva i udeo pora u prevlakama. Ispitivanja su potvrdila da su najbolji slojevi deponovani sa protokom plazma gasa od 22 l/min He. Prevlaka sa najboljim mehaničkim i strukturnim karakteristikama je testirana i homologovana na rukavcu vratila glavnog rotora helikoptera „gazela H42" letnim ispitivanjem u trajanju od 50 časova u VZ „Moma Stanojlović" u Batajnici.

  10. Struktura obitelji i životni uvjeti obitelji u selu i u gradu

    OpenAIRE

    2009-01-01

    Autori se bave strukturom i životnim uvjetima suvremene obitelji u Hrvatskoj s djecom osnovnoškolske dobi, ovisno o tome prebiva li u selu, malom i srednjem ili u velikom gradu. U analizi strukture obitelji ispitali su tko čini obitelji, te dob, stupanj obrazovanja i zanimanje članova obitelji. Životni uvjeti raščlanjeni su temeljem subjektivne procjene stambenih uvjeta obitelji te dostupnosti i rada raznih služba u lokalnoj zajednici. Ispitanici su ocijenili uvjete od...

  11. Sertifikatõ ISO - mafioznaja struktura so znakom pljuss / Olesja Bõkova

    Index Scriptorium Estoniae

    Bõkova, Olesja

    2005-01-01

    Esimesed ISO sertifikaadid, mille aluseks on briti kvaliteedi standardite süsteem, anti Euroopa Liidus välja 1987. a. ISO sertifikaadid Eestis. Diagramm: Välja antud ISO 9000 sertifikaadid 1994-2004

  12. Fiziološki značaj, struktura i metode izolacije α-laktalbumina

    OpenAIRE

    Lisak Jakopović, Katarina; Barukčić, Irena; Božanić, Rajka

    2016-01-01

    Količina proizvedene sirutke na svjetskoj razini (>2 % godišnje) neprestano raste, s obzirom da neprekidno raste i svjetska proizvodnja sira. Visoka nutritivna vrijednost sirutke zasniva se prije svega na prisustvu visokovrijednih proteina sirutke koji se odlikuju brojnim poželjnim biološkim i funkcionalnim svojstvima. Najzastupljeniji proteini sirutke su β-laktoglobulin (β-Lg) i α-laktalbumin (α-La) koji se naširoko upotrebljavaju u proizvodnji funkcionalne hrane i napitaka, te dojenačkim fo...

  13. Kapitálová struktura a její optimalizace

    OpenAIRE

    Nováková, Jana

    2012-01-01

    In this bachelor thesis, I would like to present the capital structure and its optimization. This work has two major parts. The theoretical part deals with a description of following: the structure of capital construction, valuation of company assets and liabilities and ultimately the possible optimization of capital structure. This thesis evaluates statistical data about asses of the capital adequacy of Czech companies. The practical part is evaluated in terms of a particular company and its...

  14. Zasoby mieszkaniowe Łodzi: rozwój, struktura przedmiotowa i przestrzenna

    OpenAIRE

    Dzieciuchowicz, Jerzy

    2002-01-01

    W artykule przedstawiono rozwój oraz strukturę przedmiotową i przestrzenną zasobów mieszkaniowych Łodzi, z uwzględnieniem kompleksowej oceny i typologii standardu mieszkaniowego jednostek urbanistycznych. The article is about the development, structure and spatial distribution of the housing resources in Łódź with regard to evaluation and spatial typology of habitation standard. It was found that from the beginning of the industrialisation period till the present time a cont...

  15. Sertifikatõ ISO - mafioznaja struktura so znakom pljuss / Olesja Bõkova

    Index Scriptorium Estoniae

    Bõkova, Olesja

    2005-01-01

    Esimesed ISO sertifikaadid, mille aluseks on briti kvaliteedi standardite süsteem, anti Euroopa Liidus välja 1987. a. ISO sertifikaadid Eestis. Diagramm: Välja antud ISO 9000 sertifikaadid 1994-2004

  16. Genetická struktura lokálních plemen domestikantů

    OpenAIRE

    Neradilová, Silvie

    2015-01-01

    A switch from hunting to beginnings of farming and agriculture was a crucial step for humans and for developing civilization. This period was suitable for domestication processes. Dogs were the first domesticated animals at all. Their breeding was connected with settlement and cattle protection and they were used as shepherd and hunting dogs. In some cultures they are even used as food source. Recent trends lead to breeding of new breeds and division of original gene pool into smaller closed ...

  17. Rotational structures in the {sup 125}Cs nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Singh, K.; Sihotra, S.; Mehta, D.; Singh, N. [Panjab University, Department of Physics, Chandigarh (India); Malik, S.S. [Guru Nanak Dev University, Department of Physics, Amritsar (India); Goswamy, J. [Panjab University, UIET, Chandigarh (India); Kumar, R.; Singh, R.P.; Muralithar, S. [Inter University Accelerator Centre, New Delhi (India); Paul, E.S. [University of Liverpool, Oliver Lodge Laboratory (United Kingdom); Sheikh, J.A. [University of Kashmir, Department of Physics, Kashmir (India); Praharaj, C.R. [Institute of Physics, Bhubaneshwar (India)

    2006-03-15

    The collective band structures of the {sup 125}Cs nucleus have been investigated by in-beam {gamma}-ray spectroscopic techniques following the {sup 110}Pd({sup 19}F,4n) reaction at 75 MeV. The previously known level scheme, with rotational bands built on {pi}g{sub 7/2}, {pi}g{sub 9/2} and {pi}h{sub 11/2} orbitals, has been extended and evolves into bands involving rotationally aligned {nu}(h{sub 11/2}){sup 2} and {pi}(h{sub 11/2}){sup 2} quasiparticles. A strongly coupled band has been reassigned a high-K {pi}h{sub 11/2} x {nu}g{sub 7/2} x {nu}h{sub 11/2} three-quasiparticle configuration and a new side band likely to be its chiral partner has been identified. Configurations assigned to various bands are discussed in the framework of Principal/Tilted Axis Cranking (PAC/TAC) model calculations. (orig.)

  18. Depolarizing actions of hydrogen sulfide on hypothalamic paraventricular nucleus neurons.

    Directory of Open Access Journals (Sweden)

    C Sahara Khademullah

    Full Text Available Hydrogen sulfide (H2S is a novel neurotransmitter that has been shown to influence cardiovascular functions as well and corticotrophin hormone (CRH secretion. Since the paraventricular nucleus of the hypothalamus (PVN is a central relay center for autonomic and endocrine functions, we sought to investigate the effects of H2S on the neuronal population of the PVN. Whole cell current clamp recordings were acquired from the PVN neurons and sodium hydrosulfide hydrate (NaHS was bath applied at various concentrations (0.1, 1, 10, and 50 mM. NaHS (1, 10, and 50 mM elicited a concentration-response relationship from the majority of recorded neurons, with almost exclusively depolarizing effects following administration. Cells responded and recovered from NaHS administration quickly and the effects were repeatable. Input differences from baseline and during the NaHS-induced depolarization uncovered a biphasic response, implicating both a potassium and non-selective cation conductance. The results from the neuronal population of the PVN shed light on the possible physiological role that H2S has in autonomic and endocrine function.

  19. ATG5: a distinct role in the nucleus.

    Science.gov (United States)

    Simon, Hans-Uwe; Friis, Robert

    2014-01-01

    Both apoptotic and autophagic pathways are activated in cells during anticancer treatment using DNA-damaging agents. Thus, the outcome is balanced between apoptotic cell death and enhanced autophagy, with the possibility of prolonged cell survival. It seems intuitively obvious that this survival mechanism might interfere with the desired tumor cell killing. We addressed this question by tipping the balance in favor of autophagy, using etoposide or cisplatin at low, sublethal doses. Over 4 days, only a little apoptosis was observed, but both drugs sharply increased autophagic flux. Surprisingly, cells underwent a cell cycle arrest at G 2/M, followed later by mitotic catastrophe with formation of multipolar spindles, missegregated chromosomes, or enlarged, irregular, sometimes multiple nuclei. Why? The answer is that even a low level of DNA damage not only upregulates autophagy, but also provokes the recruitment of an autophagy-related protein, ATG5, to the nucleus, where it binds BIRC5/survivin, thereby interfering with correct assembly of the chromosome passenger complex needed for cytokinesis.

  20. SUNrises on the International Plant Nucleus Consortium: SEB Salzburg 2012.

    Science.gov (United States)

    Graumann, Katja; Bass, Hank W; Parry, Geraint

    2013-01-01

    The nuclear periphery is a dynamic, structured environment, whose precise functions are essential for global processes-from nuclear, to cellular, to organismal. Its main components-the nuclear envelope (NE) with inner and outer nuclear membranes (INM and ONM), nuclear pore complexes (NPC), associated cytoskeletal and nucleoskeletal components as well as chromatin are conserved across eukaryotes (Fig. 1). In metazoans in particular, the structure and functions of nuclear periphery components are intensely researched partly because of their involvement in various human diseases. While far less is known about these in plants, the last few years have seen a significant increase in research activity in this area. Plant biologists are not only catching up with the animal field, but recent findings are pushing our advances in this field globally. In recognition of this developing field, the Annual Society of Experimental Biology Meeting in Salzburg kindly hosted a session co-organized by Katja Graumann and David E. Evans (Oxford Brookes University) highlighting new insights into plant nuclear envelope proteins and their interactions. This session brought together leading researchers with expertise in topics such as epigenetics, meiosis, nuclear pore structure and functions, nucleoskeleton and nuclear envelope composition. An open and friendly exchange of ideas was fundamental to the success of the meeting, which resulted in founding the International Plant Nucleus Consortium. This review highlights new developments in plant nuclear envelope research presented at the conference and their importance for the wider understanding of metazoan, yeast and plant nuclear envelope functions and properties.

  1. Simultaneous electrophysiological recording and calcium imaging of suprachiasmatic nucleus neurons.

    Science.gov (United States)

    Irwin, Robert P; Allen, Charles N

    2013-12-08

    Simultaneous electrophysiological and fluorescent imaging recording methods were used to study the role of changes of membrane potential or current in regulating the intracellular calcium concentration. Changing environmental conditions, such as the light-dark cycle, can modify neuronal and neural network activity and the expression of a family of circadian clock genes within the suprachiasmatic nucleus (SCN), the location of the master circadian clock in the mammalian brain. Excitatory synaptic transmission leads to an increase in the postsynaptic Ca(2+) concentration that is believed to activate the signaling pathways that shifts the rhythmic expression of circadian clock genes. Hypothalamic slices containing the SCN were patch clamped using microelectrodes filled with an internal solution containing the calcium indicator bis-fura-2. After a seal was formed between the microelectrode and the SCN neuronal membrane, the membrane was ruptured using gentle suction and the calcium probe diffused into the neuron filling both the soma and dendrites. Quantitative ratiometric measurements of the intracellular calcium concentration were recorded simultaneously with membrane potential or current. Using these methods it is possible to study the role of changes of the intracellular calcium concentration produced by synaptic activity and action potential firing of individual neurons. In this presentation we demonstrate the methods to simultaneously record electrophysiological activity along with intracellular calcium from individual SCN neurons maintained in brain slices.

  2. Recording Gamma Band Oscillations in Pedunculopontine Nucleus Neurons.

    Science.gov (United States)

    Urbano, Francisco J; Luster, Brennon R; D'Onofrio, Stasia; Mahaffey, Susan; Garcia-Rill, Edgar

    2016-09-14

    Synaptic efferents from the PPN are known to modulate the neuronal activity of several intralaminar thalamic regions (e.g., the centrolateral/parafascicular; Cl/Pf nucleus). The activation of either the PPN or Cl/Pf nuclei in vivo has been described to induce the arousal of the animal and an increment in gamma band activity in the cortical electroencephalogram (EEG). The cellular mechanisms for the generation of gamma band oscillations in Reticular Activating System (RAS) neurons are the same as those found to generate gamma band oscillations in other brains nuclei. During current-clamp recordings of PPN neurons (from parasagittal slices from 9 - 25 day-old rats), the use of depolarizing square steps rapidly activated voltage-dependent potassium channels that prevented PPN neurons from being depolarized beyond -25 mV. Injecting 1 - 2 sec long depolarizing current ramps gradually depolarized PPN membrane potential resting values towards 0 mV. However, injecting depolarizing square pulses generated gamma-band oscillations of membrane potential that showed to be smaller in amplitude compared to the oscillations generated by ramps. All experiments were performed in the presence of voltage-gated sodium channels and fast synaptic receptors blockers. It has been shown that the activation of high-threshold voltage-dependent calcium channels underlie gamma-band oscillatory activity in PPN neurons. Specific methodological and pharmacological interventions are described here, providing the necessary tools to induce and sustain PPN subthreshold gamma band oscillation in vitro.

  3. Subthalamic nucleus stimulation affects incentive salience attribution in Parkinson's disease.

    Science.gov (United States)

    Serranová, Tereza; Jech, Robert; Dušek, Petr; Sieger, Tomáš; Růžička, Filip; Urgošík, Dušan; Růžička, Evžen

    2011-10-01

    Deep brain stimulation (DBS) of the subthalamic nucleus (STN) can induce nonmotor side effects such as behavioral and mood disturbances or body weight gain in Parkinson's disease (PD) patients. We hypothesized that some of these problems could be related to an altered attribution of incentive salience (ie, emotional relevance) to rewarding and aversive stimuli. Twenty PD patients (all men; mean age ± SD, 58.3 ± 6 years) in bilateral STN DBS switched ON and OFF conditions and 18 matched controls rated pictures selected from the International Affective Picture System according to emotional valence (unpleasantness/pleasantness) and arousal on 2 independent visual scales ranging from 1 to 9. Eighty-four pictures depicting primary rewarding (erotica and food) and aversive fearful (victims and threat) and neutral stimuli were selected for this study. In the STN DBS ON condition, the PD patients attributed lower valence scores to the aversive pictures compared with the OFF condition (P weight gain correlated with arousal ratings from the food pictures in the STN DBS ON condition (P weight gain.

  4. GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats.

    Directory of Open Access Journals (Sweden)

    Lei Ding

    Full Text Available Chemical stimulation of white adipose tissue (WAT induces adipose afferent reflex (AAR, and thereby causes a general sympathetic activation. Paraventricular nucleus (PVN is important in control of sympathetic outflow. This study was designed to investigate the role of γ-aminobutyric acid (GABA in PVN in regulating the AAR.Experiments were carried out in anesthetized rats. Renal sympathetic nerve activity (RSNA and mean arterial pressure (MAP were continuously recorded. AAR was evaluated by the RSNA and MAP responses to electrical stimulation of the right epididymal WAT (eWAT afferent nerve. Electrical stimulation of eWAT afferent nerve increase RSNA. Bilateral microinjection of the GABAA receptor agonist isoguvacine or the GABAB receptor agonist baclofen attenuated the AAR. The effect of isoguvacine on the AAR was greater than that of baclofen. The GABAA receptor antagonist gabazine enhanced the AAR, while the GABAB receptor antagonist CGP-35348 had no significant effect on the AAR. Bilateral PVN microinjection of vigabatrin, a selective GABA-transaminase inhibitor, to increase endogenous GABA levels in the PVN abolished the AAR. The inhibitory effect of vigabatrin on the AAR was attenuated by the pretreatment with gabazine or CGP-35348. Pretreatment with combined gabazine and CGP-35348 abolished the effects of vigabatrin.Activation of GABAA or GABAB receptors in the PVN inhibits the AAR. Blockade of GABAA receptors in the PVN enhances the AAR. Endogenous GABA in the PVN plays an important role in regulating the AAR.

  5. In vivo histamine voltammetry in the mouse premammillary nucleus.

    Science.gov (United States)

    Samaranayake, Srimal; Abdalla, Aya; Robke, Rhiannon; Wood, Kevin M; Zeqja, Anisa; Hashemi, Parastoo

    2015-06-07

    Histamine plays a major role in the mediation of allergic reactions such as peripheral inflammation. This classical monoamine is also a neurotransmitter involved in the central nervous system but its role in this context is poorly understood. Studying histamine neurotransmission is important due to its implications in many neurological disorders. The sensitivity, selectivity and high temporal resolution of fast scan cyclic voltammetry (FSCV) offer many advantages for studying electroactive neurotransmitters. Histamine has previously been studied with FSCV; however, the lack of a robust Faradaic electrochemical signal makes it difficult to selectively identify histamine in complex media, as found in vivo. In this work, we optimize an electrochemical waveform that provides a stimulation-locked and unique electrochemical signal towards histamine. We describe in vitro waveform optimization and a novel in vivo physiological model for stimulating histamine release in the mouse premammillary nucleus via stimulation of the medial forebrain bundle. We demonstrate that a robust signal can be used to effectively identify histamine and characterize its in vivo kinetics.

  6. GUSTATORY RESPONSES OF NEURONS IN THE PARABRACHIAL NUCLEUS OF RATS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Objective:To investigate the gustatory neural response of the neurons to five basic taste stimuli in the parabrachial nucleus(PBN),Methods:Evoked responses from PBN taste neurons to tastants were recorded using standard extracellular microelectrode technique.Results:46 taste neurons were recorded in PBN,and most of them were broadly responsive.On the basis of their most effective taste stimuli,these taste neurons were classified into five types.Those are NaCl-,HCl-,quinine-sucrose-,and monosodium glutamate(MSG)-best neurons.Except for the quinine-best neurons,the responses of each best-stimulus category to its best stimulus were significantly stronger than those of others(P<0.01),The results of correlation analysis showed that the correlations between sucrose and each of the other 4 tastants were smaller than those among others.Conclusion:The results suggest that PBN taste neurons probably play an important role in discriminating for hedonic taste.

  7. GUSTATORY RESPONSES OF NEURONS IN THE PARABRACHIAL NUCLEUS OF RATS

    Institute of Scientific and Technical Information of China (English)

    黄涛; 闫剑群; 康怡

    2002-01-01

    Objective To investigate the gustatory neural r esponse of the neurons to five basic taste stimuli in the parabrachial nucleus ( PBN). Methods Evoked responses from PBN taste neurons to t astants were recorded using standard extracellular microelectrode technique. Results 46 taste neurons were recorded in PBN, and most of th em were broadly respo nsive. On the basis of their most effective taste stimuli, these taste neurons w ere classified into five types. Those are NaCl-, HCl-, quinine-, sucrose-, and monosodium glutamate (MSG)-best neurons. Except for the quinine-best neur ons, the responses of each best-stimulus category to its best stimulus were sig nificantly stronger than those of others (P<0.01). The results of correlati on analysis showed that the correlations between sucrose and each of the other 4 tastants were smaller than those among others. Conclusion Th e results suggest that PBN taste neurons probably play an important role in disc riminating for hedonic taste.

  8. Spontaneous resorption of a large cervical herniated nucleus pulposus.

    Science.gov (United States)

    Cvetanovich, Gregory L; Hsu, Andrew R; Frank, Rachel M; An, Howard S; Andersson, Gunnar B

    2014-07-01

    The majority of patients with symptomatic herniated discs can be successfully and conservatively managed and can achieve clinical improvement without surgical intervention. Resorption of the herniated nucleus pulposus (HNP) is 1 conservative mechanism for clinical improvement. We present the case of a 76-year-old healthy man with acute cervical radicular right arm pain and positive Spurling test. Magnetic resonance imaging (MRI) showed a large disc extrusion behind the C6 vertebral body, causing severe central canal stenosis and right-greater-than-left foraminal stenosis. The patient did not want surgical intervention, and his symptoms resolved with conservative treatment. A follow-up MRI 7 months after his initial presentation showed almost complete resorption of the herniated disc. The patient returned to his normal activities and has not had recurrence of symptoms for 2 years. This report provides an interesting example of complete resorption of a large, extruded cervical herniated disc in a symptomatic patient and a review of the literature on resorption of herniated discs. The review suggests that larger herniations with an epidural location (penetration of the posterior longitudinal ligament) have a greater chance of resorption.

  9. Probing Hadron Structure in Proton-Nucleus Collisions

    CERN Document Server

    Zaslavsky, David

    2014-01-01

    Understanding the behavior of large atomic nuclei (heavy ions) in high-energy collisions has been the focus of a concerted research effort over the past 10-15 years, with a recent focus on transverse momentum-dependent (or "unintegrated") parton distributions and their high-energy behavior. With the advent of high-energy proton-nucleus collisions at RHIC and the LHC, we are able to experimentally test this behavior for the first time. In this dissertation, I examine two sample predictions of this high-energy behavior. First, I analyze the azimuthal angular correlation for Drell-Yan pair and associated hadron production. I show that the correlation is a sensitive probe of the underlying gluon distribution, and a proper prediction of the correlation at all angles requires a gluon distribution with physically realistic behavior at all momenta. I'll then describe a numerical calculation of the cross section for inclusive hadron production, incorporating all corrections up to next-to-leading order in the strong co...

  10. Morphological differences in the lateral geniculate nucleus associated with dyslexia

    Directory of Open Access Journals (Sweden)

    Mónica Giraldo-Chica

    2015-01-01

    Full Text Available Developmental dyslexia is a common learning disability characterized by normal intelligence but difficulty in skills associated with reading, writing and spelling. One of the most prominent, albeit controversial, theories of dyslexia is the magnocellular theory, which suggests that malfunction of the magnocellular system in the brain is responsible for the behavioral deficits. We sought to test the basis of this theory by directly measuring the lateral geniculate nucleus (LGN, the only location in the brain where the magnocellular and parvocellular streams are spatially disjoint. Using high-resolution proton-density weighted MRI scans, we precisely measured the anatomical boundaries of the LGN in 13 subjects with dyslexia (five female and 13 controls (three female, all 22–26 years old. The left LGN was significantly smaller in volume in subjects with dyslexia and also differed in shape; no differences were observed in the right LGN. The functional significance of this asymmetry is unknown, but these results are consistent with the magnocellular theory and support theories of dyslexia that involve differences in the early visual system.

  11. The highly reduced genome of an enslaved algal nucleus.

    Science.gov (United States)

    Douglas, S; Zauner, S; Fraunholz, M; Beaton, M; Penny, S; Deng, L T; Wu, X; Reith, M; Cavalier-Smith, T; Maier, U G

    2001-04-26

    Chromophyte algae differ fundamentally from plants in possessing chloroplasts that contain chlorophyll c and that have a more complex bounding-membrane topology. Although chromophytes are known to be evolutionary chimaeras of a red alga and a non-photosynthetic host, which gave rise to their exceptional membrane complexity, their cell biology is poorly understood. Cryptomonads are the only chromophytes that still retain the enslaved red algal nucleus as a minute nucleomorph. Here we report complete sequences for all three nucleomorph chromosomes from the cryptomonad Guillardia theta. This tiny 551-kilobase eukaryotic genome is the most gene-dense known, with only 17 diminutive spliceosomal introns and 44 overlapping genes. Marked evolutionary compaction hundreds of millions of years ago eliminated nearly all the nucleomorph genes for metabolic functions, but left 30 for chloroplast-located proteins. To allow expression of these proteins, nucleomorphs retain hundreds of genetic-housekeeping genes. Nucleomorph DNA replication and periplastid protein synthesis require the import of many nuclear gene products across endoplasmic reticulum and periplastid membranes. The chromosomes have centromeres, but possibly only one loop domain, offering a means for studying eukaryotic chromosome replication, segregation and evolution.

  12. Morphological differences in the lateral geniculate nucleus associated with dyslexia.

    Science.gov (United States)

    Giraldo-Chica, Mónica; Hegarty, John P; Schneider, Keith A

    2015-01-01

    Developmental dyslexia is a common learning disability characterized by normal intelligence but difficulty in skills associated with reading, writing and spelling. One of the most prominent, albeit controversial, theories of dyslexia is the magnocellular theory, which suggests that malfunction of the magnocellular system in the brain is responsible for the behavioral deficits. We sought to test the basis of this theory by directly measuring the lateral geniculate nucleus (LGN), the only location in the brain where the magnocellular and parvocellular streams are spatially disjoint. Using high-resolution proton-density weighted MRI scans, we precisely measured the anatomical boundaries of the LGN in 13 subjects with dyslexia (five female) and 13 controls (three female), all 22-26 years old. The left LGN was significantly smaller in volume in subjects with dyslexia and also differed in shape; no differences were observed in the right LGN. The functional significance of this asymmetry is unknown, but these results are consistent with the magnocellular theory and support theories of dyslexia that involve differences in the early visual system.

  13. Regulation of nucleus accumbens activity by the hypothalamic neuropeptide MCH

    Science.gov (United States)

    Sears, Robert M.; Liu, Rong-Jian; Narayanan, Nandakumar S.; Sharf, Ruth; Yeckel, Mark F.; Laubach, Mark; Aghajanian, George K.; DiLeone, Ralph J.

    2010-01-01

    The lateral hypothalamus (LH) and the nucleus accumbens shell (AcbSh) are brain regions important for food intake. The AcbSh contains high levels of receptor for melanin-concentrating hormone (MCH), a lateral hypothalamic peptide critical for feeding and metabolism. MCH receptor (MCHR1) activation in the AcbSh increases food intake while AcbSh MCHR1 blockade reduces feeding. Here biochemical and cellular mechanisms of MCH action in the rodent AcbSh are described. A reduction of phosphorylation of GluR1 at Serine 845 (pSer845) is shown to occur after both pharmacological and genetic manipulations of MCHR1 activity. These changes depend upon signaling through Gi/o, and result in decreased surface expression of GluR1-containing AMPA receptors (AMPARs). Electrophysiological analysis of medium spiny neurons (MSNs) in the AcbSh revealed decreased amplitude of AMPAR-mediated synaptic events (mEPSC) with MCH treatment. In addition, MCH suppressed action potential firing MSNs through K+ channel activation. Finally, in vivo recordings confirmed that MCH reduces neuronal cell firing in the AcbSh in freely moving animals. The ability of MCH to reduce cell firing in the AcbSh is consistent with a general model from other pharmacological and electrophysiological studies whereby reduced AcbSh neuronal firing leads to food intake. The current work integrates the hypothalamus into this model, providing biochemical and cellular mechanisms whereby metabolic and limbic signals converge to regulate food intake. PMID:20554878

  14. The sperm nucleus: chromatin, RNA and the nuclear matrix

    Science.gov (United States)

    Johnson, Graham D.; Lalancette, Claudia; Linnemann, Amelia K.; Leduc, Frédéric; Boissonneault, Guylain; Krawetz, Stephen A.

    2017-01-01

    Within the sperm nucleus the paternal genome remains functionally inert and protected following protamination. This is marked by a structural morphogenesis that is heralded by a striking reduction in nuclear volume. Despite these changes, both human and mouse spermatozoa maintain low levels of nucleosomes that appear non-randomly distributed throughout the genome. These regions may be necessary for organizing higher order genomic structure through interactions with the nuclear matrix. The promoters of this transcriptionally quiescent genome are differentially marked by modified histones that may poise downstream epigenetic effects. This notion is supported by increasing evidence that the embryo inherits these differing levels of chromatin organization. In concert with the suite of RNAs retained in the mature sperm they may synergistically interact to direct early embryonic gene expression. Irrespective, these features reflect the transcriptional history of spermatogenic differentiation. As such they may soon be utilized as clinical markers of male fertility. In this review we explore and discuss how this may be orchestrated. PMID:20876223

  15. On the origin of shape fluctuations of the cell nucleus.

    Science.gov (United States)

    Chu, Fang-Yi; Haley, Shannon C; Zidovska, Alexandra

    2017-09-26

    The nuclear envelope (NE) presents a physical boundary between the cytoplasm and the nucleoplasm, sandwiched in between two highly active systems inside the cell: cytoskeleton and chromatin. NE defines the shape and size of the cell nucleus, which increases during the cell cycle, accommodating for chromosome decondensation followed by genome duplication. In this work, we study nuclear shape fluctuations at short time scales of seconds in human cells. Using spinning disk confocal microscopy, we observe fast fluctuations of the NE, visualized by fluorescently labeled lamin A, and of the chromatin globule surface (CGS) underneath the NE, visualized by fluorescently labeled histone H2B. Our findings reveal that fluctuation amplitudes of both CGS and NE monotonously decrease during the cell cycle, serving as a reliable cell cycle stage indicator. Remarkably, we find that, while CGS and NE typically fluctuate in phase, they do exhibit localized regions of out-of-phase motion, which lead to separation of NE and CGS. To explore the mechanism behind these shape fluctuations, we use biochemical perturbations. We find the shape fluctuations of CGS and NE to be both thermally and actively driven, the latter caused by forces from chromatin and cytoskeleton. Such undulations might affect gene regulation as well as contribute to the anomalously high rates of nuclear transport by, e.g., stirring of molecules next to NE, or increasing flux of molecules through the nuclear pores.

  16. Oxytocin excites nucleus accumbens shell neurons in vivo.

    Science.gov (United States)

    Moaddab, Mahsa; Hyland, Brian I; Brown, Colin H

    2015-09-01

    Oxytocin modulates reward-related behaviors. The nucleus accumbens shell (NAcSh) is a major relay in the brain reward pathway and expresses oxytocin receptors, but the effects of oxytocin on the activity of NAcSh neurons in vivo are unknown. Hence, we used in vivo extracellular recording to show that intracerebroventricular (ICV) oxytocin administration (0.2μg) robustly increased medial NAcSh neuron mean firing rate; this increase was almost exclusively evident in slow-firing neurons and was not associated with any change in firing pattern. To determine whether oxytocin excitation of medial NAcSh neurons is modulated by drugs that impact the brain reward pathway, we next tested the effects of ICV oxytocin following repeated morphine treatment. In morphine-treated rats, ICV oxytocin did not affect the mean firing rate of medial NAcSh neurons. Taken together, these results show that oxytocin excites medial NAcSh neurons but does not do so after repeated morphine. This could be an important factor in oxytocin modulation of reward-related behaviors, such as drug addiction.

  17. Tryptophan synthase of Phaeophyceae originated from the secondary host nucleus

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yalan; CHI Shan; WU Shuangxiu; LIU Cui; YU Jun; WANG Xumin; CHEN Shengping; LIU Tao

    2014-01-01

    Tryptophan synthase (TS, EC 4.2.1.20) catalyzes the last two steps of L-tryptophan biosynthesis. In pro-karyotes, tryptophan synthase is a multi-enzyme complex, and it consists ofαandβsubunit which forms anα-ββ-αcomplex. In fungi and diatoms, TS is a bifunctional enzyme. Because of the limited genomic and transcriptomic data of algae, there are few studies on TS evolution of algae. Here we analyzed the data of the 1000 Plants Project (1KP), and focused on red algae and brown algae. We found out that the TS of Phaeophy-ceae were fusion genes, which probably originated from the secondary host nucleus, and that the TS of Rho-dophyta contained two genes, TSA and TSB, which both display a possible cyanobacterial origin at the time of primary endosymbiosis. In addition, there were two types of TSB genes (TSB1 and TSB2). Through the multiple sequence alignment of TSB proteins, we found several residues conserved in TSB1 but variable in TSB2 which connect withαsubunit. The phenomenon may suggest that the TSB2 sequences of Rhodophyta cannot form stable complex with TSA.

  18. Dopaminergic stimulation of subthalamic nucleus elicits oral dyskinesia in rats.

    Science.gov (United States)

    Parry, T J; Eberle-Wang, K; Lucki, I; Chesselet, M F

    1994-08-01

    The effects of dopaminergic stimulation of the subthalamic nucleus (STh) on motor behavior were examined in conscious rats. Unilateral infusion of apomorphine (0.1 to 3.2 micrograms) into the STh induced a dose-dependent increase in abnormal, nondirected orofacial movements without altering turning, sniffing, grooming, or rearing behaviors. Orofacial movements elicited by local infusion of apomorphine (1.0 microgram) into the STh were blocked by peripheral administration of the D1 antagonist, SCH 23390 (0.1 mg/kg, sc), but not by the D2 antagonists haloperidol (1.0 mg/kg, sc) or sulpiride (50 mg/kg, sc). Furthermore, coinfusion of SCH 23390 (1.0 microgram), but not sulpiride (5.0 micrograms), with apomorphine (1.0 microgram) into the STh blocked oral dyskinesia. Oral movements could not be reelicited by an infusion of apomorphine into the STh after a kainic acid lesion of the STh. In addition, infusion of apomorphine (1.0 microgram) into sites proximal to but deliberately outside of the STh failed to elicit nondirected oral movements above baseline levels. The results indicate that stimulation of D1 dopaminergic receptors within the STh induces abnormal orofacial movements. This highlights the importance of the dopaminergic input to the STh in the regulation of motor function and suggests that D1 receptor antagonists could prove useful in the treatment of orofacial dyskinesia in humans.

  19. The planetary nebula Abell 48 and its [WN4] nucleus

    CERN Document Server

    Frew, David J; Parker, Q A; Stupar, M; Wachter, S; DePew, K; Danehkar, A; Fitzgerald, M F

    2013-01-01

    We have conducted a detailed multi-wavelength study of the peculiar planetary nebula Abell 48 and its central star. We present evidence for a new classification of the nucleus as a helium-rich, hydrogen-deficient star of type [WN4], one of only two currently known examples of its type. The evidence for either a massive WN or a low-mass [WN] interpretation is critically examined, and we firmly conclude that Abell 48 is a planetary nebula around an evolved low-mass star, rather than a Population I ejecta nebula. Importantly, the surrounding nebula has a morphology typical of planetary nebulae, and is not enriched in nitrogen, and thus not the 'peeled atmosphere' of a massive star. We estimate a distance of 1.6 kpc and a reddening, E(B-V) = 1.90 mag, the latter value clearly showing the nebula lies on the near side of the Galactic bar, and therefore cannot be a massive WN star. The planetary nebula has an ionized mass (0.3 M_sun) and electron density (740 cm^-3) typical of somewhat evolved objects. The observed ...

  20. Multiparametric characterization of neuronal subpopulations in the ventrolateral preoptic nucleus.

    Science.gov (United States)

    Dubourget, Romain; Sangare, Aude; Geoffroy, Hélène; Gallopin, Thierry; Rancillac, Armelle

    2017-04-01

    The characterization of neuronal properties is a necessary first step toward understanding how the ventrolateral preoptic nucleus (VLPO) neuronal network regulates slow-wave sleep (SWS). Indeed, the electrophysiological heterogeneity of VLPO neurons suggests the existence of subtypes that could differently contribute in SWS induction and maintenance. The aim of the present study was to define cell classes in the VLPO using an unsupervised clustering classification method. Electrophysiological features extracted from 289 neurons recorded in whole-cell patch-clamp allowed the identification of three main classes of VLPO neurons subdivided into five distinct subpopulations (cluster 1, 2a, 2b, 3a and 3b). The high occurrence of a low-threshold calcium spike (LTS) was one of the most distinctive features of cluster 1 and 3. Since sleep-promoting neurons are generally identified by their ability to generate an LTS and by their inhibitory response to noradrenaline (NA), 189 neurons from our dataset were also tested for this neurotransmitter. Neurons from cluster 3 were the most frequently inhibited by NA. Biocytin labeling and Neurolucida reconstructions of 112 neurons furthermore revealed a small dendritic arbor of cluster 3b neurons compared, in particular, to cluster 2b neurons. Altogether, we performed an exhaustive characterization of VLPO neuronal subtypes that is a crucial step toward a better understanding of the neuronal network within the VLPO and thereby sleep physiology.

  1. Neuronal Complexity in Subthalamic Nucleus is Reduced in Parkinson's Disease.

    Science.gov (United States)

    Vyas, Saurabh; Huang, He; Gale, John T; Sarma, Sridevi V; Montgomery, Erwin B

    2016-01-01

    Several theories posit increased Subthalamic Nucleus (STN) activity is causal to Parkinsonism, yet in our previous study we showed that activity from 113 STN neurons from two epilepsy patients and 103 neurons from nine Parkinson's disease (PD) patients demonstrated no significant differences in frequencies or in the coefficients of variation of mean discharge frequencies per 1-s epochs. We continued our analysis using point process modeling to capture higher order temporal dynamics; in particular, bursting, beta-band oscillations, excitatory and inhibitory ensemble interactions, and neuronal complexity. We used this analysis as input to a logistic regression classifier and were able to differentiate between PD and epilepsy neurons with an accuracy of 92%. We also found neuronal complexity, i.e., the number of states in a neuron's point process model, and inhibitory ensemble dynamics, which can be interpreted as a reduction in complexity, to be the most important features with respect to classification accuracy. Even in a dataset with no significant differences in firing rate, we observed differences between PD and epilepsy for other single-neuron measures. Our results suggest PD comes with a reduction in neuronal "complexity," which translates to a neuron's ability to encode information; the more complexity, the more information the neuron can encode. This is also consistent with studies correlating disease to loss of variability in neuronal activity, as the lower the complexity, the less variability.

  2. D¯ D meson pair production in antiproton-nucleus collisions

    Science.gov (United States)

    Shyam, R.; Tsushima, K.

    2016-10-01

    We study the D ¯D (D¯0D0 and D-D+) charm meson pair production in antiproton (p ¯) induced reactions on nuclei at beam energies ranging from threshold to several GeV. Our model is based on an effective Lagrangian approach that has only the baryon-meson degrees of freedom and involves the physical hadron masses. The reaction proceeds via the t -channel exchanges of Λc+, Σc+, and Σc++ baryons in the initial collision of the antiproton with one of the protons of the target nucleus. The medium effects on the exchanged baryons are included by incorporating in the corresponding propagators, the effective charm baryon masses calculated within a quark-meson coupling (QMC) model. The wave functions of the bound proton have been determined within the QMC model as well as in a phenomenological model where they are obtained by solving the Dirac equation with appropriate scalar and vector potentials. The initial- and final-state distortion effects have been approximated by using an eikonal approximation-based procedure. Detailed numerical results are presented for total and double differential cross sections for the D¯0D0 and D-D+ production reactions on 16O and 90Zr targets. It is noted that at p ¯ beam momenta of interest to the P ¯ ANDA experiment, medium effects lead to noticeable enhancements in the charm meson production cross sections.

  3. Consolidation of altered associability information by amygdala central nucleus.

    Science.gov (United States)

    Schiffino, Felipe L; Holland, Peter C

    2016-09-01

    The surprising omission of a reinforcer can enhance the associability of the stimuli that were present when the reward prediction error was induced, so that they more readily enter into new associations in the future. Previous research from this laboratory identified brain circuit elements critical to the enhancement of stimulus associability by the omission of an expected event and to the subsequent expression of that altered associability in more rapid learning. These elements include the amygdala, the midbrain substantia nigra, the basal forebrain substantia innominata, the dorsolateral striatum, the secondary visual cortex, and the posterior parietal cortex. Here, we found that consolidation of a surprise-enhanced associability memory in a serial prediction task depends on processing in the amygdala central nucleus (CeA) after completion of sessions that included the surprising omission of an expected event. Post-surprise infusions of anisomycin, lidocaine, or muscimol prevented subsequent display of surprise-enhanced associability. Because previous studies indicated that CeA function is unnecessary for the expression of associability enhancements that were induced previously when CeA function was intact (Holland & Gallagher, 2006), we interpreted these results as indicating that post-surprise activity of CeA ("surprise replay") is necessary for the consolidation of altered associability memories elsewhere in the brain, such as the posterior parietal cortex (Schiffino et al., 2014a).

  4. Microtubules contribute to maintain nucleus shape in epithelial cell monolayer

    Science.gov (United States)

    Tremblay, Dominique; Andrzejewski, Lukasz; Pelling, Andrew

    2013-03-01

    INTRODUCTION: Tissue strains can result in significant nuclear deformations and may regulate gene expression. However, the precise role of the cytoskeleton in regulating nuclear mechanics remains poorly understood. Here, we investigate the nuclear deformability of Madin-Darky canine kidney cells (MDCK) under various stretching conditions to clarify the role of the microtubules and actin network on the mechanical behavior of the nucleus. METHODS: A custom-built cell-stretching device allowing for real time imaging of MDCK nuclei was used. Cells were seeded on a silicone membrane coated with rat-tail collagen I. A nuclear stain, Hoechst-33342, was used to image nuclei during stretching. We exposed cells to a compressive and non-compressive stretching strain field of 25%. Nocodazole and cytochalasin-D were used to depolymerize the microtubules and actin network. RESULTS: Nuclei in control cells stretched more along their minor axis than major axis with a deformation of 5% and 2% respectively. This anisotropy vanished completely in microtubule-deprived cells and these cells showed a very high nuclear deformability along the minor axis when exposed to a compressive stretching strain field. CONCLUSIONS: The microtubules drive the anisotropic deformability of MDCK nuclei in a monolayer and maintain nuclear shape when exposed to compressive strain. Such intrinsic mechanical behavior indicates that microtubules are essential to maintain nuclear shape and may prevent down regulation of gene expression.

  5. On Parallel Streams through the Mouse Dorsal Lateral Geniculate Nucleus

    Directory of Open Access Journals (Sweden)

    Daniel eDenman

    2016-03-01

    Full Text Available The mouse visual system is an emerging model for the study of cortical and thalamic circuit function. To maximize the usefulness of this model system, it is important to analyze the similarities and differences between the organization of all levels of the murid visual system with other, better studied systems (e.g., non-human primates and the domestic cat. While the understanding of mouse retina and cortex has expanded rapidly, less is known about mouse dorsal lateral geniculate nucleus (dLGN. Here, we study whether parallel processing streams exist in mouse dLGN. We use a battery of stimuli that have been previously shown to successfully distinguish parallel streams in other species: electrical stimulation of the optic chiasm, contrast-reversing stationary gratings at varying spatial phase, drifting sinusoidal gratings, dense noise for receptive field reconstruction, and frozen contrast-modulating noise. As in the optic nerves of domestic cats and non-human primates, we find evidence for multiple conduction velocity groups after optic chiasm stimulation. As in so-called ‘visual mammals’, we find a subpopulation of mouse dLGN cells showing non-linear spatial summation. However, differences in stimulus selectivity and sensitivity do not provide sufficient basis for identification of clearly distinct classes of relay cells. Nevertheless, consistent with presumptively homologous status of dLGNs of all mammals, there are substantial similarities between response properties of mouse dLGN neurons and those of cats and primates.

  6. Decay Properties of the Halo Nucleus $^{11}$Li

    CERN Multimedia

    2002-01-01

    During the past years a considerable experimental effort has been devoted to the production and study of nuclei close to the neutron and proton drip-lines. The most spectacular phenomenon encountered is the occurrence of neutron halos in the loosely bound neutron rich nuclei. \\\\ \\\\ Another interesting feature, observed at ISOLDE, which most likely is connected to the halo structure, is the very strong (super-allowed) Gamow-Teller $\\beta$- transitions to highly excited states which are systematically observed for the lightest neutron rich drip-line nuclei. These transitions might be viewed as arising from the quasi-free $\\beta$ -decay of the halo neutrons. It is proposed to make a detailed study of the $\\beta$- strength function for $^{11}$Li, a nuclide having a half-life of 8.2 ms and a Q $\\beta$-value of 20.73~MeV. \\\\ \\\\ So far only a lower limit of the Gamow-Teller transition rate to highly excited states ($\\approx$~18.5~MeV) in the daughter nucleus has been obtained from measurements of $\\beta$-delayed tri...

  7. Contour Detection of Leukocyte Cell Nucleus Using Morphological Image

    Science.gov (United States)

    Supriyanti, R.; Satrio, G. P.; Ramadhani, Y.; Siswandari, W.

    2017-04-01

    Leukocytes are blood cells that do not contain color pigments. Leukocyte function to the tool body’s defenses. Abnormal forms of leukocytes can be a sign of serious diseases such example is leukemia. Most laboratories still use cell morphology examination to assist the diagnosis of illness associated with white blood cells such example is leukemia because of limited resources, both infrastructure, and human resources as happens in developing nations, such as Indonesia. This examination is less expensive and quicker process. However, morphological review requires the expertise of a specialist clinical pathology were limited. This process is sometimes less valid cause in some cases trying to differentiate morphology blast cells into the type of myoblasts, lymphoblast, monoblast, or erythroblast thus potentially misdiagnosis. The goal of this research is to develop a detection device types of blood cells automatically as lower-priced, easy to use and accurate so that the tool can be distributed across all units in existing health services throughout Indonesia and in particular for remote areas. However, because the variables used in the identification of abnormal leukocytes are very complex, in this paper, we emphasize on the contour detection of leukocyte cell nucleus using the morphological image. The results show that this method is promising for further development.

  8. Whole transcriptome organisation in the dehydrated supraoptic nucleus

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    C.C.T. Hindmarch

    2013-12-01

    Full Text Available The supraoptic nucleus (SON is part of the central osmotic circuitry that synthesises the hormone vasopressin (Avp and transports it to terminals in the posterior lobe of the pituitary. Following osmotic stress such as dehydration, this tissue undergoes morphological, electrical and transcriptional changes to facilitate the appropriate regulation and release of Avp into the circulation where it conserves water at the level of the kidney. Here, the organisation of the whole transcriptome following dehydration is modelled to fit Zipf's law, a natural power law that holds true for all natural languages, that states if the frequency of word usage is plotted against its rank, then the log linear regression of this is -1. We have applied this model to our previously published euhydrated and dehydrated SON data to observe this trend and how it changes following dehydration. In accordance with other studies, our whole transcriptome data fit well with this model in the euhydrated SON microarrays, but interestingly, fit better in the dehydrated arrays. This trend was observed in a subset of differentially regulated genes and also following network reconstruction using a third-party database that mines public data. We make use of language as a metaphor that helps us philosophise about the role of the whole transcriptome in providing a suitable environment for the delivery of Avp following a survival threat like dehydration.

  9. PREFACE: Hot Quarks 2014: Workshop for young scientists on the physics of ultrarelativistic nucleus-nucleus collisions

    Science.gov (United States)

    2015-05-01

    The 6th edition of the Workshop for Young Scientists on the Physics of Ultrarelativistic Nucleus-Nucleus Collisions (Hot Quarks 2014) was held in Las Negras, Spain from 21-28 September 2014. Following the traditions of the conference, this meeting gathered more than 70 participants in the first years of their scientific careers. The present issue contains the proceedings of this workshop. As in the past, the Hot Quarks workshop offered a unique atmosphere for a lively discussion and interpretation of the current measurements from high energy nuclear collisions. Recent results and upgrades at CERN's Large Hadron Collider (LHC) and Brookhaven's Relativistic Heavy Ion Collider (RHIC) were presented. Recent theoretical developments were also extensively discussed as well as the perspectives for future facilities such as the Facility for Antiproton and Ion Research (FAIR) at Darmstadt and the Electron-Ion Collider at Brookhaven. The conference's goal to provide a platform for young researchers to learn and foster their interactions was successfully met. We wish to thank the sponsors of the Hot Quarks 2014 Conference, who supported the authors of this volume: Brookhaven National Laboratory (USA), CPAN (Spain), Czech Science Foundation (GACR) under grant 13-20841S (Czech Republic), European Laboratory for Particle Physics CERN (Switzerland), European Research Council under grant 259612 (EU), ExtreMe Matter Institute EMMI (Germany), Helmholtz Association and GSI under grant VH-NG-822, Helmholtz International Center for FAIR (Germany), National Science Foundation under grant No.1359622 (USA), Nuclear Physics Institute ASCR (Czech Republic), Patronato de la Alhambra y Generalife (Spain) and the Universidad de Granada (Spain). Javier López Albacete, Universidad de Granada (Spain) Jana Bielcikova, Nuclear Physics Inst. and Academy of Sciences (Czech Republic) Rainer J. Fries, Texas A&M University (USA) Raphaël Granier de Cassagnac, CNRS-IN2P3 and École polytechnique (France

  10. Squish and squeeze-the nucleus as a physical barrier during migration in confined environments.

    Science.gov (United States)

    McGregor, Alexandra Lynn; Hsia, Chieh-Ren; Lammerding, Jan

    2016-06-01

    From embryonic development to cancer metastasis, cell migration plays a central role in health and disease. It is increasingly becoming apparent that cells migrating in three-dimensional (3-D) environments exhibit some striking differences compared with their well-established 2-D counterparts. One key finding is the significant role the nucleus plays during 3-D migration: when cells move in confined spaces, the cell body and nucleus must deform to squeeze through available spaces, and the deformability of the large and relatively rigid nucleus can become rate-limiting. In this review, we highlight recent findings regarding the role of nuclear mechanics in 3-D migration, including factors that govern nuclear deformability, and emerging mechanisms by which cells apply cytoskeletal forces to the nucleus to facilitate nuclear translocation. Intriguingly, the 'physical barrier' imposed by the nucleus also impacts cytoplasmic dynamics that affect cell migration and signaling, and changes in nuclear structure resulting from the mechanical forces acting on the nucleus during 3-D migration could further alter cellular function. These findings have broad relevance to the migration of both normal and cancerous cells inside living tissues, and motivate further research into the molecular details by which cells move their nuclei, as well as the consequences of the mechanical stress on the nucleus.

  11. Age-related structural and functional changes in the cochlear nucleus.

    Science.gov (United States)

    Frisina, Robert D; Walton, Joseph P

    2006-01-01

    Presbycusis - age-related hearing loss - is a key communication disorder and chronic medical condition of our aged population. The cochlear nucleus is the major site of projections from the auditory portion of the inner ear. Relative to other levels of the peripheral and central auditory systems, relatively few studies have been conducted examining age-related changes in the cochlear nucleus. The neurophysiological investigations suggest declines in glycine-mediated inhibition, reflected in increased firing rates in cochlear nucleus neurons from old animals relative to young adults. Biochemical investigations of glycine inhibition in the cochlear nucleus are consistent with the functional aging declines of this inhibitory neurotransmitter system that affect complex sound processing. Anatomical reductions in neurons of the cochlear nucleus and their output pathways can occur due to aging changes in the brain, as well as due to age-dependent plasticity of the cochlear nucleus in response to the age-related loss of inputs from the cochlea, particularly from the basal, high-frequency regions. Novel preventative and curative biomedical interventions in the future aimed at alleviating the hearing loss that comes with age, will likely emanate from increasing our knowledge and understanding of its neural and molecular bases. To the extent that this sensory deficit resides in the central auditory system, including the cochlear nucleus, future neural therapies will be able to improve hearing in the elderly.

  12. M-CSF TARGETING INTO LCL NUCLEUS BEHAVES AS A MALIGNANCY PROMOTOR

    Institute of Scientific and Technical Information of China (English)

    曹震宇; 吴克复; 宋玉华; 李戈; 林永敏; 饶青; 马小彤

    2003-01-01

    Objective: To investigate the functions of nM-CSF in malignant cells. Methods: recombinant M-CSF was targeted into cell nucleus by employing a eukaryotic expression plasmid vector pCMV/myc/nuc. The constructed plasmid was transfected into cells of EBV transformed lymphoblastoid cell line (LCL). RT-PCR, Western blot and immunofluorescent staining showed that recombinant M-CSF was localized into LCL cell nucleus. The transgenic cells showed elevated proliferation potential, enhanced resistance to apoptosis and increased ability of in vitro migration. Conclusion: Nucleus presenting M-CSF might act as a promoting factor in the processes of cell malignancy.

  13. LEVEL DENSITY AND FINITE-TEMPERATURE SPECIFIC HEATOF NUCLEUS 104pd UNDER MICROSCOPIC IBM

    Institute of Scientific and Technical Information of China (English)

    石筑一; 刘庸; 桑建平

    2001-01-01

    By using the microscopic sdgIBM-Fmax approach, the procedure of canonical ensemble average and the saddle point approximation, the thermodynamics of the nucleus is established under microscopic IBM. Calculations of spectrum, level density and finite-temperature specific heat for the nucleus 104pd are carried out. The calculated values are coincident with the experimental data reported recently. The results predict that the shape phase transition in the groundstate band appears at about T ≈0.230MeV and the phase transition of the thermal excitation mode takes place at T ≈0.630 MeV for the nucleus 104pd.

  14. Comparative differential gene expression analysis of nucleus-encoded proteins for Rafflesia cantleyi against Arabidopsis thaliana

    Science.gov (United States)

    Ng, Siuk-Mun; Lee, Xin-Wei; Wan, Kiew-Lian; Firdaus-Raih, Mohd

    2015-09-01

    Regulation of functional nucleus-encoded proteins targeting the plastidial functions was comparatively studied for a plant parasite, Rafflesia cantleyi versus a photosynthetic plant, Arabidopsis thaliana. This study involved two species of different feeding modes and different developmental stages. A total of 30 nucleus-encoded proteins were found to be differentially-regulated during two stages in the parasite; whereas 17 nucleus-encoded proteins were differentially-expressed during two developmental stages in Arabidopsis thaliana. One notable finding observed for the two plants was the identification of genes involved in the regulation of photosynthesis-related processes where these processes, as expected, seem to be present only in the autotroph.

  15. Variational treatment of the confined hydrogen atom with a moving nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, Francisco M, E-mail: fernande@quimica.unlp.edu.a [INIFTA (UNLP, CCT La Plata-CONICET), Division Quimica Teorica, Blvd. 113 S/N, Sucursal 4, Casilla de Correo 16, 1900 La Plata (Argentina)

    2010-05-15

    We solve the Schroedinger equation for a hydrogen atom within a spherical box approximately by means of the variational method. We propose two simple trial functions for the case in which both the nucleus and the electron move within the box. Present results are sufficiently accurate for all values of the box radius and therefore an improvement on an earlier calculation based on perturbation theory. We compare the energies of three alternative approaches for the moving-nucleus model with that of the nucleus clamped at origin. We also outline some physical applications of the model.

  16. Shuttling of the autoantigen La between nucleus and cell surface after uv irradiation of human keratinocytes

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, M.; Chang, S.; Slor, H.; Kukulies, J.; Mueller, W.E. (Universitaet, Mainz (Germany, F.R.))

    1990-12-01

    During the past years we have established that the nuclear autoantigen La shuttles between the nucleus and the cytoplasm in tumor cells after inhibition of transcription or virus infection. We reinvestigated this shuttling using primary human keratinocytes from both healthy donors and patients with xeroderma pigmentosum. Ultraviolet irradiation resulted in both an inhibition of transcription and a translocation of La protein from the nucleus to the cytoplasm. After a prolonged inhibition of transcription La protein relocated into the nucleus and assembled with nuclear storage regions. The uv-induced shuttling included a translocation to the cell surface, where La protein colocalized with epidermal growth factor receptors.

  17. Reduced nucleus accumbens and caudate nucleus activation to a pleasant taste is associated with obesity in older adults.

    Science.gov (United States)

    Green, Erin; Jacobson, Aaron; Haase, Lori; Murphy, Claire

    2011-04-22

    Although obesity is recognized as a global health epidemic, insufficient research has been directed to understanding the rising prevalence of obesity in the fastest growing segment of the population, older adults. Late-life obesity has been linked to declines in physical health and cognitive function, with implications not only for the individual, but also for society. We investigated the hypothesis that altered brain responses to food reward is associated with obesity, using fMRI of response to pleasant and aversive taste stimuli in young and older adults performing a hedonic evaluation task. Correlations between higher levels of abdominal fat/body mass index and reduced fMRI activation to sucrose in dopamine-related brain regions (caudate, nucleus accumbens) were large in older adults. Significant associations between a hypofunctioning reward response and obesity suggest the hypothesis that decreased dopamine functioning may be a plausible mechanism for weight gain in older adults. Copyright © 2011 Elsevier B.V. All rights reserved.

  18. Weakly interacting massive particle-nucleus elastic scattering response

    Science.gov (United States)

    Anand, Nikhil; Fitzpatrick, A. Liam; Haxton, W. C.

    2014-06-01

    Background: A model-independent formulation of weakly interacting massive particle (WIMP)-nucleon scattering was recently developed in Galilean-invariant effective field theory. Purpose: Here we complete the embedding of this effective interaction in the nucleus, constructing the most general elastic nuclear cross section as a factorized product of WIMP and nuclear response functions. This form explicitly defines what can and cannot be learned about the low-energy constants of the effective theory—and consequently about candidate ultraviolet theories of dark matter—from elastic scattering experiments. Results: We identify those interactions that cannot be reliably treated in a spin-independent/spin-dependent (SI/SD) formulation: For derivative- or velocity-dependent couplings, the SI/SD formulation generally mischaracterizes the relevant nuclear operator and its multipolarity (e.g., scalar or vector) and greatly underestimates experimental sensitivities. This can lead to apparent conflicts between experiments when, in fact, none may exist. The new nuclear responses appearing in the factorized cross section are related to familiar electroweak nuclear operators such as angular momentum l⃗(i) and the spin-orbit coupling σ⃗(i).l⃗(i). Conclusions: To unambiguously interpret experiments and to extract all of the available information on the particle physics of dark matter, experimentalists will need to (1) do a sufficient number of experiments with nuclear targets having the requisite sensitivities to the various operators and (2) analyze the results in a formalism that does not arbitrarily limit the candidate operators. In an appendix we describe a code that is available to help interested readers implement such an analysis.

  19. Nucleus of the active Centaur C/2011 P2 (PANSTARRS)

    Science.gov (United States)

    Mazzotta Epifani, E.; Perna, D.; Dotto, E.; Palumbo, P.; Dall'Ora, M.; Micheli, M.; Ieva, S.; Perozzi, E.

    2017-01-01

    Aims: In this paper we present observations of the active Centaur C/2011 P2 (PANSTARRS), showing a compact comet-like coma at the heliocentric distance of rh = 9 au. The observations were obtained in the framework of a wider program on Centaurs aimed at searching for comet-like activity in several targets outside Jupiter's aphelion. Methods: We analysed visible images of the Centaur taken at the TNG telescope in the R filter to investigate the level of coma contributing to the target brightness and to derive information on its nucleus size. Results: Centaur C/2011 P2 (PANSTARRS) shows a faint but still detectable comet-like activity, which accounts for more than 50% to the observed brightness. The coma contribution has been subtracted in order to derive an estimate for the Centaur's diameter of D 16 km, assuming an albedo of A = 0.07 (average of albedo measured within the Centaur group). The results for Centaur C/2011 P2 (PANSTARRS) fit in the general picture of the group: Centaurs with smaller perihelion distance q and semi-major axis a are smaller than those remaining farther from the Sun during their orbital path, thus reinforcing the idea that active Centaurs are "comets in fieri". Based on observations collected at the Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the Centro Galileo Galilei of the INAF (Istituto Nazionale di Astrofisica) at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias.

  20. Subthalamic nucleus stimulation and somatosensory temporal discrimination in Parkinson's disease.

    Science.gov (United States)

    Conte, Antonella; Modugno, Nicola; Lena, Francesco; Dispenza, Sabrina; Gandolfi, Barbara; Iezzi, Ennio; Fabbrini, Giovanni; Berardelli, Alfredo

    2010-09-01

    Whereas numerous studies document the effects of dopamine medication and deep brain stimulation on motor function in patients with Parkinson's disease, few have investigated deep brain stimulation-induced changes in sensory functions. In this study of 13 patients with Parkinson's disease, we tested the effects of deep brain stimulation on the somatosensory temporal discrimination threshold. To investigate whether deep brain stimulation and dopaminergic medication induce similar changes in somatosensory discrimination, somatosensory temporal discrimination threshold values were acquired under four experimental conditions: (i) medication ON/deep brain stimulation on; (ii) medication ON/deep brain stimulation off; (iii) medication OFF/deep brain stimulation on; and (iv) medication OFF/deep brain stimulation off. Patients also underwent clinical and neuropsychological evaluations during each experimental session. Somatosensory temporal discrimination threshold values obtained in patients were compared with 13 age-matched healthy subjects. Somatosensory temporal discrimination threshold values were significantly higher in patients than in healthy subjects. In patients, somatosensory temporal discrimination threshold values were significantly lower when patients were studied in medication ON than in medication OFF conditions. Somatosensory temporal discrimination threshold values differed significantly between deep brain stimulation on and deep brain stimulation off conditions only when the patients were studied in the medication ON condition and were higher in the deep brain stimulation on/medication ON than in the deep brain stimulation off/medication ON condition. Dopamine but not subthalamic nucleus deep brain stimulation restores the altered somatosensory temporal discrimination in patients with Parkinson's disease. Deep brain stimulation degrades somatosensory temporal discrimination by modifying central somatosensory processing whereas dopamine restores the