Sample records for 3-dimensional traction forces

  1. Modeling traction forces in collective cell migration

    Zimmermann, Juliane; Basan, Markus; Hayes, Ryan L.; Rappel, Wouter-Jan; Levine, Herbert


    Collective cell migration is an important process in embryonic development, wound healing, and cancer metastasis. We have developed a particle-based simulation for collective cell migration that describes flow patterns and finger formation at the tissue edge observed in wound healing experiments. We can apply methods for calculating intercellular stress to our simulation model, and have thereby provided evidence for the validity of a stress reconstitution method from traction forces used in experiments. To accurately capture experimentally measured traction forces and stresses in the tissue, which are mostly tensile, we have to include intracellular acto-myosin contraction into our simulation. We can then reproduce the experimentally observed behavior of cells moving around a circular obstacle, and suggest underlying mechanisms for cell-cell alignment and generation of traction force patterns.

  2. Measurement of cell traction forces with ImageJ.

    Martiel, Jean-Louis; Leal, Aldo; Kurzawa, Laetitia; Balland, Martial; Wang, Irene; Vignaud, Timothée; Tseng, Qingzong; Théry, Manuel


    The quantification of cell traction forces requires three key steps: cell plating on a deformable substrate, measurement of substrate deformation, and the numerical estimation of the corresponding cell traction forces. The computing steps to measure gel deformation and estimate the force field have somehow limited the adoption of this method in cell biology labs. Here we propose a set of ImageJ plug-ins so that every lab equipped with a fluorescent microscope can measure cell traction forces.

  3. Rigid two-axis MEMS force plate for measuring cellular traction force

    Takahashi, Hidetoshi; Jung, Uijin G.; Kan, Tetsuo; Tsukagoshi, Takuya; Matsumoto, Kiyoshi; Shimoyama, Isao


    Cellular traction force is one of the important factors for understanding cell behaviors, such as spreading, migration and differentiation. Cells are known to change their behavior according to the mechanical stiffness of the environment. However, the measurement of cell traction forces on a rigid environment has remained difficult. This paper reports a micro-electromechanical systems (MEMS) force plate that provides a cellular traction force measurement on a rigid substrate. Both the high force sensitivity and high stiffness of the substrate were obtained using piezoresistive sensing elements. The proposed force plate consists of a 70 µm  ×  15 µm  ×  5 µm base as the substrate for cultivating a bovine aortic smooth muscle cell, and the supporting beams with piezoresistors on the sidewall and the surface were used to measure the forces in both the horizontal and vertical directions. The spring constant and force resolution of the fabricated force plate in the horizontal direction were 0.2 N m-1 and less than 0.05 µN, respectively. The cell traction force was measured, and the traction force increased by approximately 1 µN over 30 min. These results demonstrate that the proposed force plate is applicable as an effective traction force measurement.

  4. Traction Force and Tension Fluctuations During Axon Growth

    Jamison ePolackwich


    Full Text Available Actively generated mechanical forces play a central role in axon growthand guidance, but the mechanisms that underly force generation andregulation in growing axons remain poorly understood. We reportmeasurements of the dynamics of traction stresses from growth cones ofactively advancing axons from postnatal rat DRG neurons. By tracking themovement of the growth cone and analyzing the traction stress field froma reference frame that moves with it, we are able to show that there isa clear and consistent average stress field that underlies the complexspatial stresses present at any one time. The average stress field hasstrong maxima on the sides of the growth cone, directed inward towardthe growth cone neck. This pattern represents a contractile stresscontained within the growth cone, and a net force that is balanced bythe axon tension. Using high time-resolution measurements of the growthcone traction stresses, we show that the stress field is composed offluctuating local stress peaks, with a large number peaks that live fora short time, a population of peaks whose lifetime distribution followsan exponential decay, and a small number of very long-lived peaks. Weshow that the high time-resolution data also reveal that the tensionappears to vary randomly over short time scales, roughly consistent withthe lifetime of the stress peaks, suggesting that the tensionfluctuations originate from stochastic adhesion dynamics.

  5. Traction Forces of Endothelial Cells under Slow Shear Flow

    Perrault, Cecile M.; Brugues, Agusti; Bazellieres, Elsa; Ricco, Pierre; Lacroix, Damien; Trepat, Xavier


    Endothelial cells are constantly exposed to fluid shear stresses that regulate vascular morphogenesis, homeostasis, and disease. The mechanical responses of endothelial cells to relatively high shear flow such as that characteristic of arterial circulation has been extensively studied. Much less is known about the responses of endothelial cells to slow shear flow such as that characteristic of venous circulation, early angiogenesis, atherosclerosis, intracranial aneurysm, or interstitial flow. Here we used a novel, to our knowledge, microfluidic technique to measure traction forces exerted by confluent vascular endothelial cell monolayers under slow shear flow. We found that cells respond to flow with rapid and pronounced increases in traction forces and cell-cell stresses. These responses are reversible in time and do not involve reorientation of the cell body. Traction maps reveal that local cell responses to slow shear flow are highly heterogeneous in magnitude and sign. Our findings unveil a low-flow regime in which endothelial cell mechanics is acutely responsive to shear stress. PMID:26488643

  6. Matrix identity and tractional forces influence indirect cardiac reprogramming

    Kong, Yen P.; Carrion, Bita; Singh, Rahul K.; Putnam, Andrew J.


    Heart regeneration through in vivo cardiac reprogramming has been demonstrated as a possible regenerative strategy. While it has been reported that cardiac reprogramming in vivo is more efficient than in vitro, the influence of the extracellular microenvironment on cardiac reprogramming remains incompletely understood. This understanding is necessary to improve the efficiency of cardiac reprogramming in order to implement this strategy successfully. Here we have identified matrix identity and cell-generated tractional forces as key determinants of the dedifferentiation and differentiation stages during reprogramming. Cell proliferation, matrix mechanics, and matrix microstructure are also important, but play lesser roles. Our results suggest that the extracellular microenvironment can be optimized to enhance cardiac reprogramming.


    B. Ye. Bodnar


    Full Text Available Purpose. The article describes the most common methods for determining the locomotive traction force. Solving the tasks of traction calculations involves determination of the forces influencing the train at every point of the way. When choosing a rational trajectory of the train motion and the development of operational regulations of train driving it is necessary to determine the actual value of the locomotive traction force. Considering various factors, power value of traction electric motor of locomotive may have significant differences. Advancement of the operational definition system of the locomotive traction force during the calculations by electrical parameters of traction electric motor with regard to uneven load of wheel-motor block is the purpose of the article. Methodology. The method of determining the traction force of locomotives and diesel locomotives with electric transmission, which is based on primary data acquisition of traction electric engines of direct current behavior, was proposed. Sensors and their integration into the electrical circuitry of the locomotive in order to get the data in digital form and for operational calculation of the each traction motor mode and the definition of locomotive traction force are presented. Findings. The experimental investigation of the system of locomotive traction force determination with the electric traction motor ED-105 was offered. A comparison of electrical and mechanical power of the electric motor was conducted. Originality. The system of locomotives power operational definition, which takes into account the variable electro-mechanical factors of wheel and motor blocks and increases the accuracy of the calculations, was proposed. Practical value. The system is a part of an onboard complex in definition of energy-efficient regimes for trains movement and provides the definition of accelerating and decelerating forces.

  8. Scaling of traction forces with the size of cohesive cell colonies.

    Mertz, Aaron F; Banerjee, Shiladitya; Che, Yonglu; German, Guy K; Xu, Ye; Hyland, Callen; Marchetti, M Cristina; Horsley, Valerie; Dufresne, Eric R


    To understand how the mechanical properties of tissues emerge from interactions of multiple cells, we measure traction stresses of cohesive colonies of 1-27 cells adherent to soft substrates. We find that traction stresses are generally localized at the periphery of the colony and the total traction force scales with the colony radius. For large colony sizes, the scaling appears to approach linear, suggesting the emergence of an apparent surface tension of the order of 10(-3)  N/m. A simple model of the cell colony as a contractile elastic medium coupled to the substrate captures the spatial distribution of traction forces and the scaling of traction forces with the colony size.

  9. For whom the cells pull: Hydrogel and micropost devices for measuring traction forces.

    Ribeiro, Alexandre J S; Denisin, Aleksandra K; Wilson, Robin E; Pruitt, Beth L


    While performing several functions, adherent cells deform their surrounding substrate via stable adhesions that connect the intracellular cytoskeleton to the extracellular matrix. The traction forces that deform the substrate are studied in mechanotrasduction because they are affected by the mechanics of the extracellular milieu. We review the development and application of two methods widely used to measure traction forces generated by cells on 2D substrates: (i) traction force microscopy with polyacrylamide hydrogels and (ii) calculation of traction forces with arrays of deformable microposts. Measuring forces with these methods relies on measuring substrate displacements and converting them into forces. We describe approaches to determine force from displacements and elaborate on the necessary experimental conditions for this type of analysis. We emphasize device fabrication, mechanical calibration of substrates and covalent attachment of extracellular matrix proteins to substrates as key features in the design of experiments to measure cell traction forces with polyacrylamide hydrogels or microposts. We also report the challenges and achievements in integrating these methods with platforms for the mechanical stimulation of adherent cells. The approaches described here will enable new studies to understand cell mechanical outputs as a function of mechanical inputs and advance the understanding of mechanotransduction mechanisms.

  10. Traction Control of Electric Vehicles Using Sliding-Mode Controller with Tractive Force Observer

    Suwat Kuntanapreeda


    Full Text Available Traction control is an important element in modern vehicles to enhance drive efficiency, safety, and stability. Traction is produced by friction between tire and road, which is a nonlinear function of wheel slip. In this paper, a sliding-mode control approach is used to design a robust traction controller. The control objective is to operate vehicles such that a desired wheel slip ratio is achieved. A nonlinearity observer is employed to estimate tire tractive forces, which are used in the control law. Simulation and experimental results have illustrated the success of the proposed observer-based controller.

  11. The regulation of traction force in relation to cell shape and focal adhesions.

    Rape, Andrew D; Guo, Wei-Hui; Wang, Yu-Li


    Mechanical forces provide critical inputs for proper cellular functions. The interplay between the generation of, and response to, mechanical forces regulate such cellular processes as differentiation, proliferation, and migration. We postulate that adherent cells respond to a number of physical and topographical factors, including cell size and shape, by detecting the magnitude and/or distribution of traction forces under different conditions. To address this possibility we introduce a new simple method for precise micropatterning of hydrogels, and then apply the technique to systematically investigate the relationship between cell geometry, focal adhesions, and traction forces in cells with a series of spread areas and aspect ratios. Contrary to previous findings, we find that traction force is not determined primarily by the cell spreading area but by the distance from cell center to the perimeter. This distance in turn controls traction forces by regulating the size of focal adhesions, such that constraining the size of focal adhesions by micropatterning can override the effect of geometry. We propose that the responses of traction forces to center-periphery distance, possibly through a positive feedback mechanism that regulates focal adhesions, provide the cell with the information on its own shape and size. A similar positive feedback control may allow cells to respond to a variety of physical or topographical signals via a unified mechanism.

  12. Time-dependent traction force microscopy for cancer cells as a measure of invasiveness.

    Peschetola, Valentina; Laurent, Valérie M; Duperray, Alain; Michel, Richard; Ambrosi, Davide; Preziosi, Luigi; Verdier, Claude


    The migration of tumor cells of different degrees of invasivity is studied, on the basis of the traction forces exerted in time on soft substrates (Young modulus∼10 kPa). It is found that the outliers of the traction stresses can be an effective indicator to distinguish cancer cell lines of different invasiveness. Here, we test two different epithelial bladder cancer cell lines, one invasive (T24), and a less invasive one (RT112). Invasive cancer cells move in a nearly periodic motion, with peaks in velocity corresponding to higher traction forces exerted on the substrate, whereas less invasive cells develop traction stresses almost constant in time. The dynamics of focal adhesions (FAs) as well as cytoskeleton features reveals that different mechanisms are activated to migrate: T24 cells show an interconnected cytoskeleton linked to mature adhesion sites, leading to small traction stresses, whereas less invasive cells (RT112) show a less-structured cytoskeleton and unmature adhesions corresponding to higher traction stresses. Migration velocities are smaller in the case of less invasive cells. The mean squared displacement shows super-diffusive motion in both cases with higher exponent for the more invasive cancer cells. Further correlations between traction forces and the actin cytoskeleton reveal an unexpected pattern of a large actin rim at the RT112 cell edge where higher forces are colocalized, whereas a more usual cytoskeleton structure with stress fibers and FAs are found for T24 cancer cells. We conjecture that this kind of analysis can be useful to classify cancer cell invasiveness.

  13. The study of 3-dimensional structures of IgG with atomic force microscopy

    YU Yi-gang; XU Ru-xiang; JIANG Xiao-dan; KE Yi-quan


    Objective: To detect 3-dimensional images of anti-N-methyl-D-aspartate receptor Nr1 (NMDAr1) polycolonal IgG affixed on mica in physiological environment. Methods: The images and data were obtained from a contact mode and commercial Si3N4 probed tip by using atomic force microscope (AFM). Conclusions: Using AFM to investigate biomacromolecule can make us deeply understand the structure of IgG, which will instruct us to detect the membrane receptor protein as a labelling agent.

  14. The Regulation of Traction Force in Relation to Cell Shape and Focal Adhesions

    Rape, Andrew; Guo, Wei-hui; Wang, Yu-Li


    Mechanical forces provide critical inputs for proper cellular functions. The interplay between the generation of, and response to, mechanical forces regulate such cellular processes as differentiation, proliferation, and migration. We postulate that adherent cells respond to a number of physical and topographical factors, including cell size and shape, by detecting the magnitude and/or distribution of traction forces under different conditions. To address this possibility we introduce a new s...

  15. Quantifying the Traction Force of a Single Cell by Aligned Silicon Nanowire Array

    Li, Zhou


    The physical behaviors of stationary cells, such as the morphology, motility, adhesion, anchorage, invasion and metastasis, are likely to be important for governing their biological characteristics. A change in the physical properties of mammalian cells could be an indication of disease. In this paper, we present a silicon-nanowire-array based technique for quantifying the mechanical behavior of single cells representing three distinct groups: normal mammalian cells, benign cells (L929), and malignant cells (HeLa). By culturing the cells on top of NW arrays, the maximum traction forces of two different tumor cells (HeLa, L929) have been measured by quantitatively analyzing the bending of the nanowires. The cancer cell exhibits a larger traction force than the normal cell by ∼20% for a HeLa cell and ∼50% for a L929 cell. The traction forces have been measured for the L929 cells and mechanocytes as a function of culture time. The relationship between cells extending area and their traction force has been investigated. Our study is likely important for studying the mechanical properties of single cells and their migration characteristics, possibly providing a new cellular level diagnostic technique. © 2009 American Chemical Society.


    Ivanov, A.; А. Timkov


    The method calculation wich can been used to determine the distribution of traction and braking force of the vehicle in different driving cycles and use it when choosing characteristics of a hybrid vehicle deviced. The differential equation of vehicle’s motion basis of Newton’s second law lies in the basis of the given methodology.

  17. Model-based traction force microscopy reveals differential tension in cellular actin bundles.

    Soiné, Jérôme R D; Brand, Christoph A; Stricker, Jonathan; Oakes, Patrick W; Gardel, Margaret L; Schwarz, Ulrich S


    Adherent cells use forces at the cell-substrate interface to sense and respond to the physical properties of their environment. These cell forces can be measured with traction force microscopy which inverts the equations of elasticity theory to calculate them from the deformations of soft polymer substrates. We introduce a new type of traction force microscopy that in contrast to traditional methods uses additional image data for cytoskeleton and adhesion structures and a biophysical model to improve the robustness of the inverse procedure and abolishes the need for regularization. We use this method to demonstrate that ventral stress fibers of U2OS-cells are typically under higher mechanical tension than dorsal stress fibers or transverse arcs.

  18. Creep force modelling for rail traction vehicles based on the Fastsim algorithm

    Spiryagin, Maksym; Polach, Oldrich; Cole, Colin


    The evaluation of creep forces is a complex task and their calculation is a time-consuming process for multibody simulation (MBS). A methodology of creep forces modelling at large traction creepages has been proposed by Polach [Creep forces in simulations of traction vehicles running on adhesion limit. Wear. 2005;258:992-1000; Influence of locomotive tractive effort on the forces between wheel and rail. Veh Syst Dyn. 2001(Suppl);35:7-22] adapting his previously published algorithm [Polach O. A fast wheel-rail forces calculation computer code. Veh Syst Dyn. 1999(Suppl);33:728-739]. The most common method for creep force modelling used by software packages for MBS of running dynamics is the Fastsim algorithm by Kalker [A fast algorithm for the simplified theory of rolling contact. Veh Syst Dyn. 1982;11:1-13]. However, the Fastsim code has some limitations which do not allow modelling the creep force - creep characteristic in agreement with measurements for locomotives and other high-power traction vehicles, mainly for large traction creep at low-adhesion conditions. This paper describes a newly developed methodology based on a variable contact flexibility increasing with the ratio of the slip area to the area of adhesion. This variable contact flexibility is introduced in a modification of Kalker's code Fastsim by replacing the constant Kalker's reduction factor, widely used in MBS, by a variable reduction factor together with a slip-velocity-dependent friction coefficient decreasing with increasing global creepage. The proposed methodology is presented in this work and compared with measurements for different locomotives. The modification allows use of the well recognised Fastsim code for simulation of creep forces at large creepages in agreement with measurements without modifying the proven modelling methodology at small creepages.

  19. Flexible substrata for the detection of cellular traction forces

    Beningo, Karen A.; Wang, Yu-Li


    By modulating adhesion signaling and cytoskeletal organization, mechanical forces play an important role in various cellular functions, from propelling cell migration to mediating communication between cells. Recent developments have resulted in several new approaches for the detection, analysis and visualization of mechanical forces generated by cultured cells. Combining these methods with other approaches, such as green-fluorescent protein (GFP) imaging and gene manipulation, proves to be particularly powerful for analyzing the interplay between extracellular physical forces and intracellular chemical events.

  20. Cadherin-Based Intercellular Adhesions Organize Epithelial Cell-Matrix Traction Forces

    Mertz, Aaron F; Banerjee, Shiladitya; Goldstein, Jill; Rosowski, Kathryn R; Niessen, Carien M; Marchetti, M Cristina; Dufresne, Eric R; Horsley, Valerie


    Cell--cell and cell-matrix adhesions play essential roles in the function of tissues. There is growing evidence for the importance of crosstalk between these two adhesion types, yet little is known about the impact of these interactions on the mechanical coupling of cells to the extracellular-matrix (ECM). Here, we combine experiment and theory to reveal how intercellular adhesions modulate forces transmitted to the ECM. In the absence of cadherin-based adhesions, primary mouse keratinocytes within a colony appear to act independently, with significant traction forces extending throughout the colony. In contrast, with strong cadherin-based adhesions, keratinocytes in a cohesive colony localize traction forces to the colony periphery. Through genetic or antibody-mediated loss of cadherin expression or function, we show that cadherin-based adhesions are essential for this mechanical cooperativity. A minimal physical model in which cell--cell adhesions modulate the physical cohesion between contractile cells is ...

  1. Deletion of the cytoplasmic domain of N-cadherin reduces, but does not eliminate, traction force-transmission.

    Lee, Eliot; Ewald, Makena L; Sedarous, Mary; Kim, Timothy; Weyers, Brent W; Truong, Rose Hong; Yamada, Soichiro


    Collective migration of epithelial cells is an integral part of embryonic development, wound healing, tissue renewal and carcinoma invasion. While previous studies have focused on cell-extracellular matrix adhesion as a site of migration-driving, traction force-transmission, cadherin mediated cell-cell adhesion is also capable of force-transmission. Using a soft elastomer coated with purified N-cadherin as a substrate and a Hepatocyte Growth Factor-treated, transformed MDCK epithelial cell line as a model system, we quantified traction transmitted by N-cadherin-mediated contacts. On a substrate coated with purified extracellular domain of N-cadherin, cell surface N-cadherin proteins arranged into puncta. N-cadherin mutants (either the cytoplasmic deletion or actin-binding domain chimera), however, failed to assemble into puncta, suggesting the assembly of focal adhesion like puncta requires the cytoplasmic domain of N-cadherin. Furthermore, the cytoplasmic domain deleted N-cadherin expressing cells exerted lower traction stress than the full-length or the actin binding domain chimeric N-cadherin. Our data demonstrate that N-cadherin junctions exert significant traction stress that requires the cytoplasmic domain of N-cadherin, but the loss of the cytoplasmic domain does not completely eliminate traction force transmission.

  2. A simple and efficient quasi 3-dimensional viscoelastic model and software for simulation of tapping-mode atomic force microscopy.

    Solares, Santiago D


    This paper introduces a quasi-3-dimensional (Q3D) viscoelastic model and software tool for use in atomic force microscopy (AFM) simulations. The model is based on a 2-dimensional array of standard linear solid (SLS) model elements. The well-known 1-dimensional SLS model is a textbook example in viscoelastic theory but is relatively new in AFM simulation. It is the simplest model that offers a qualitatively correct description of the most fundamental viscoelastic behaviors, namely stress relaxation and creep. However, this simple model does not reflect the correct curvature in the repulsive portion of the force curve, so its application in the quantitative interpretation of AFM experiments is relatively limited. In the proposed Q3D model the use of an array of SLS elements leads to force curves that have the typical upward curvature in the repulsive region, while still offering a very low computational cost. Furthermore, the use of a multidimensional model allows for the study of AFM tips having non-ideal geometries, which can be extremely useful in practice. Examples of typical force curves are provided for single- and multifrequency tapping-mode imaging, for both of which the force curves exhibit the expected features. Finally, a software tool to simulate amplitude and phase spectroscopy curves is provided, which can be easily modified to implement other controls schemes in order to aid in the interpretation of AFM experiments.

  3. Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading.

    Benjamin J Dubin-Thaler

    Full Text Available Actin-based cell motility and force generation are central to immune response, tissue development, and cancer metastasis, and understanding actin cytoskeleton regulation is a major goal of cell biologists. Cell spreading is a commonly used model system for motility experiments -- spreading fibroblasts exhibit stereotypic, spatially-isotropic edge dynamics during a reproducible sequence of functional phases: 1 During early spreading, cells form initial contacts with the surface. 2 The middle spreading phase exhibits rapidly increasing attachment area. 3 Late spreading is characterized by periodic contractions and stable adhesions formation. While differences in cytoskeletal regulation between phases are known, a global analysis of the spatial and temporal coordination of motility and force generation is missing. Implementing improved algorithms for analyzing edge dynamics over the entire cell periphery, we observed that a single domain of homogeneous cytoskeletal dynamics dominated each of the three phases of spreading. These domains exhibited a unique combination of biophysical and biochemical parameters -- a motility module. Biophysical characterization of the motility modules revealed that the early phase was dominated by periodic, rapid membrane blebbing; the middle phase exhibited continuous protrusion with very low traction force generation; and the late phase was characterized by global periodic contractions and high force generation. Biochemically, each motility module exhibited a different distribution of the actin-related protein VASP, while inhibition of actin polymerization revealed different dependencies on barbed-end polymerization. In addition, our whole-cell analysis revealed that many cells exhibited heterogeneous combinations of motility modules in neighboring regions of the cell edge. Together, these observations support a model of motility in which regions of the cell edge exhibit one of a limited number of motility modules

  4. Characterization of Intracellular Streaming and Traction Forces in Migrating Physarum Plasmodia

    Zhang, Shun; Del Alamo, Juan C.; Guy, Robert D.; Lasheras, Juan C.


    Physarum plasmodium is a model organism for cell migration that exhibits fast intracellular streaming. Motile amoeboid physarum plasmodia were obtained from dish cultures of Physarum Polycephalum, a slime mold that inhabits shady cool moist areas in the wild, such as decaying vegetable material. The migrating amoebae were obtained by cutting successively smaller pieces from the growing tips of the cultured parent mold, and their size ranged 0.2 to 0.5 mm. Single amoebae were seeded and let adhere on flexible polyacrilamide gels that were functionalized with collagen, contained 0.2-micron fluorescent beads, and were embedded in an aqueous medium. Soon after adhering to the gel, the amoeabe began crawling at about 1mm/hr. Joint time-lapse sequences of intracellular streaming and gel deformation were acquired respectively in the bright and fluorescent fields of a confocal microscope at 20X magnification. These images were analyzed using particle-tracking algorithms, and the traction stresses applied by the amoebae on the surface were computed by solving the elastostatic equation for the gel using the measured bead displacements as boundary conditions. These measurements provide, for the first time, a joint characterization of intracellular mass transport and the forces driving this transport in motile amoeboid cells.

  5. Non-regularised Inverse Finite Element Analysis for 3D Traction Force Microscopy

    Munoz, Jose J


    The tractions that cells exert on a gel substrate from the observed displacements is an increasingly attractive and valuable information in biomedical experiments. The computation of these tractions requires in general the solution of an inverse problem. Here, we resort to the discretisation with finite elements of the associated direct variational formulation, and solve the inverse analysis using a least square approach. This strategy requires the minimisation of an error functional, which is usually regularised in order to obtain a stable system of equations with a unique solution. In this paper we show that for many common three-dimensional geometries, meshes and loading conditions, this regularisation is unnecessary. In these cases, the computational cost of the inverse problem becomes equivalent to a direct finite element problem. For the non-regularised functional, we deduce the necessary and sufficient conditions that the dimensions of the interpolated displacement and traction fields must preserve in ...

  6. Development And Use Of Advanced Microfabricated Traction Force Sensing Substrates To Study The Effect of Nanosilver On Human Macrophages

    Stark, Daniel Thomas

    While nanoparticles are a natural byproduct of combustion and a number of natural processes, engineered nanoparticles have only recently entered the consumer market. This motivates the development of methods for studying their effects on human cells, thereby indicating how larger models such as animals and humans might react to them. This research develops a method to mechanically characterize cellular traction forces as a measure of exposure to nanoparticles. To do this, 1microm micropillar molds were fabricated in silicon wafers using smooth sidewall reactive ion plasma etching technologies. Polydimethylsiloxane (PDMS), was cured inside the silicon molds, subsequently treated for cell culture and used to measure cellular traction forces over time in live cell time-lapse experiments. For the first time, transmitted light was used to visualize the PDMS micropillars; a force resolution of 5.6 +/-2.1nN was achieved across all experiments using a standard Olympus IX81 confocal microscope affixed with a 60x NA2.1 objective. To initiate cellular movement, monocyte chemoattractant protein (MCP-1) was conjugated to 1microm latex beads. The effects of 40nm silver nanoparticle exposures were quantified using the micropillar array. Changes in cellular behavior between the control group and cells exposed to nanosilver were not significant, although a comparison between the 5microg/ml and 10microg/ml nanosilver concentrations yielded strong significance using a 2 sided Students t test.

  7. Young adult patient with two palatally maxillary impacted canines and forced traction on rigid arches of stabilization. Case report



    SUMMARY Objective Young adult patient treated for impaction of two maxillary canines. Methods C.S., 15 years, female. Diagnostic evaluation by clinical and radiographic examinations shows permanent dentition with persistence of 5.3 and 6.3, impaction of 1.3 and 2.3, dento-skeletal Cl I malocclusion, normodivergence of bone bases. Analysis of TC dentalscan confirms the palatal impaction of 1.3 and 2.3. The treatment plan provided an orthodontic-surgical approach for adequate space management in dental arch, evaluation of eruption movements, choice of anchorage device, surgical exposure and application of the brackets. Results Deciduous canines have been extracted and an edgewise appliance with rigid rectangular full thickness archwires has been used to align the arches and to obtain maximum anchorage during the forced traction. The surgical phase, for exposure of 1.3 and 2.3 respectively, performed an open technique by excisional uncovering and a close technique by a repositioned flap. The case has been finalized for the achievement of the right occlusal keys. Conclusion The possibility to choose the surgical technique depending on the intraosseous position of impacted teeth in association to the edgewise therapy with full thickness arches allows to realize an effectiveness surgical-orthodontic approach for the forced traction of impacted teeth in a favourable position. PMID:28042427

  8. Computerized identification and classification of stance phases as made by front or hind feet of walking cows based on 3-dimensional ground reaction forces

    Skjøth, Flemming; Thorup, V. M.; do Nascimento, Omar Feix


    Lameness is a frequent disorder in dairy cows and in large dairy herds manual lameness detection is a time-consuming task. This study describes a method for automatic identification of stance phases in walking cows, and their classification as made by a front or a hind foot based on ground reaction...... force information. Features were derived from measurements made using two parallel 3-dimensional force plates. The approach presented is based on clustering of Centre of Pressure (COP) trace points over space and time, combined with logical sequencing of stance phases based on the dynamics...

  9. Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

    Yu, Cheng-han; Rafiq, Nisha Bte Mohd; Cao, Fakun; Zhou, Yuhuan; Krishnasamy, Anitha; Biswas, Kabir Hassan; Ravasio, Andrea; Chen, Zhongwen; Wang, Yu-Hsiu; Kawauchi, Keiko; Jones, Gareth E.; Sheetz, Michael P.


    The turnover of integrin receptors is critical for cell migration and adhesion dynamics. Here we find that force development at integrins regulates adaptor protein recruitment and endocytosis. Using mobile RGD (Arg-Gly-Asp) ligands on supported lipid membranes (RGD membranes) and rigid RGD ligands on glass (RGD-glass), we find that matrix force-dependent integrin signals block endocytosis. Dab2, an adaptor protein of clathrin-mediated endocytosis, is not recruited to activated integrin-beta3 clusters on RGD-glass; however, it is recruited to integrin-mediated adhesions on RGD membranes. Further, when force generation is inhibited on RGD-glass, Dab2 binds to integrin-beta3 clusters. Dab2 binding to integrin-beta3 excludes other adhesion-related adaptor proteins, such as talin. The clathrin-mediated endocytic machinery combines with Dab2 to facilitate the endocytosis of RGD-integrin-beta3 clusters. From these observations, we propose that loss of traction force on ligand-bound integrin-beta3 causes recruitment of Dab2/clathrin, resulting in endocytosis of integrins. PMID:26507506

  10. Cell origami: self-folding of three-dimensional cell-laden microstructures driven by cell traction force.

    Kaori Kuribayashi-Shigetomi

    Full Text Available This paper describes a method of generating three-dimensional (3D cell-laden microstructures by applying the principle of origami folding technique and cell traction force (CTF. We harness the CTF as a biological driving force to fold the microstructures. Cells stretch and adhere across multiple microplates. Upon detaching the microplates from a substrate, CTF causes the plates to lift and fold according to a prescribed pattern. This self-folding technique using cells is highly biocompatible and does not involve special material requirements for the microplates and hinges to induce folding. We successfully produced various 3D cell-laden microstructures by just changing the geometry of the patterned 2D plates. We also achieved mass-production of the 3D cell-laden microstructures without causing damage to the cells. We believe that our methods will be useful for biotechnology applications that require analysis of cells in 3D configurations and for self-assembly of cell-based micro-medical devices.

  11. Cell Origami: Self-Folding of Three-Dimensional Cell-Laden Microstructures Driven by Cell Traction Force

    Kuribayashi-Shigetomi, Kaori; Onoe, Hiroaki; Takeuchi, Shoji


    This paper describes a method of generating three-dimensional (3D) cell-laden microstructures by applying the principle of origami folding technique and cell traction force (CTF). We harness the CTF as a biological driving force to fold the microstructures. Cells stretch and adhere across multiple microplates. Upon detaching the microplates from a substrate, CTF causes the plates to lift and fold according to a prescribed pattern. This self-folding technique using cells is highly biocompatible and does not involve special material requirements for the microplates and hinges to induce folding. We successfully produced various 3D cell-laden microstructures by just changing the geometry of the patterned 2D plates. We also achieved mass-production of the 3D cell-laden microstructures without causing damage to the cells. We believe that our methods will be useful for biotechnology applications that require analysis of cells in 3D configurations and for self-assembly of cell-based micro-medical devices. PMID:23251426

  12. Micropillar displacements by cell traction forces are mechanically correlated with nuclear dynamics

    Li, Qingsen; Makhija, Ekta; Hameed, F.M. [Mechanobiology Institute, National University of Singapore (Singapore); Shivashankar, G.V., E-mail: [Mechanobiology Institute, National University of Singapore (Singapore); Department of Biological Sciences, National University of Singapore (Singapore)


    Cells sense physical cues at the level of focal adhesions and transduce them to the nucleus by biochemical and mechanical pathways. While the molecular intermediates in the mechanical links have been well studied, their dynamic coupling is poorly understood. In this study, fibroblast cells were adhered to micropillar arrays to probe correlations in the physical coupling between focal adhesions and nucleus. For this, we used novel imaging setup to simultaneously visualize micropillar deflections and EGFP labeled chromatin structure at high spatial and temporal resolution. We observed that micropillar deflections, depending on their relative positions, were positively or negatively correlated to nuclear and heterochromatin movements. Our results measuring the time scales between micropillar deflections and nucleus centroid displacement are suggestive of a strong elastic coupling that mediates differential force transmission to the nucleus. - Highlights: • Correlation between focal adhesions and nucleus studied using novel imaging setup. • Micropillar and nuclear displacements were measured at high resolution. • Correlation timescales show strong elastic coupling between cell edge and nucleus.

  13. MR-Imaging optimisation of the articular hip cartilage by using a T{sub 1}-weighted 3-dimensional gradient-echo sequence and the application of a hip joint traction; Magnetresonanztomographische Optimierung der Hueftknorpeldarstellung durch die Wahl einer T{sub 1}-Volumen-Gradienten-Echo-Sequenz und die Anwendung einer Hueftgelenkstraktion

    Rosenberg, R. [Heidelberg Univ. (Germany). Orthopaedische Klinik und Poliklinik; Bernd, L. [Heidelberg Univ. (Germany). Orthopaedische Klinik und Poliklinik; Wrazidlo, W. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo; Lederer, W. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo; Schneider, S. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo


    Images of three animal cadaver hips, 8 dissected patient femoral heads and 18 hip joints of human corpses, all either with arthrosis stage I-III or artificial cartilage defects, were compared with their corresponding anatomic sections. Additional histomorphologic examinations of the arthrotic cartilages were conducted, and MR-Imaging of 20 healthy and 21 arthrotic patient hips was performed using a specific traction method. Using a T{sub 1}-weighted 3-dimensional gradient-echo sequence and a traction of the hip joint, it was possible due to the low-signal imaging of the joint space to separate in vivo the high-signal femoral head cartilage from the high-signal acetabular cartilage. In horizontal position of the phase-encoding parameter, minimisation of the chemical-shift artifact, mainly in the ventro-lateral areas, was accomplished. MRI measurements of the articular cartilage widths showed significant correlations (p < 0.001) with the corresponding anatomic sections. At the same time the T{sub 1} 3-dimensional gradient-echo sequence of the lateral femoral head with r = 0.94 showed the lowest deviations of the measurements. It was possible with MR-Imaging to distinguish four cartilage qualities. (orig./MG) [Deutsch] Im experimentellen Teil der Studie wurden den MRT-Bildern von drei Kadavertierhueften, 8 resezierten Patientenhueftkoepfen und 18 Leichenhueftgelenken, an denen entweder artifizielle Knorpeldefekte gesetzt wurden oder die ein Koxarthrose-Stadium I-III aufwiesen, die korrespondierenden makroskopischen Kryomikrotomschnitte zugeordnet. Bei den Koxarthrosen erfolgten zusaetzliche histomorphologische Knorpeluntersuchungen. Im klinischen Teil der Studie wurden 20 gesunde und 21 arthrotische Probandenhueftgelenke mit einem speziellen Traktionsverfahren untersucht. Unter Anwendung einer T{sub 1}-Volumen-Gradienten-Echo-Sequenz und einer Traktion am zu untersuchenden Hueftgelenk konnte in vivo durch die signalarme Darstellung des Gelenkspaltes der

  14. The initial effects of orthopedic forces: a study of alterations in the craniofacial complex of a macerated human skull owing to high-pull headgear traction.

    Kragt, G; Duterloo, H S


    The initial reaction of components of the craniofacial skeleton of a macerated human skull was studied after high-pull headgear traction. The applied forces were increased step by step from 0.5 N to 3.25 N per side (1N = 100 grams). Laser holography was used for measuring displacements in three dimensions in seventeen indicator points on the skull. These points were located near sutures or on the outer surface of individual bones. The skull was observed from the right frontal and from the left lateral side. Results indicate that displacements range from 0 micrometer to 17.0 micrometers, depending on force magnitude and on the location of the observed point. Individual components of the craniofacial skeleton were mostly displaced in a horizontal backward direction when the skull was viewed from the frontal aspect. Various compression and shearing patterns were observed in the craniofacial sutures, apparently depending on their spatial locations and intersutural surface morphology.

  15. Role of Tractional Forces and Internal Limiting Membrane in Macular Hole Formation: Insights from Intraoperative Optical Coherence Tomography

    Elad Moisseiev


    Full Text Available We report the case of a 69-year-old patient who underwent vitrectomy for vitreomacular traction (VMT and developed a postoperative macular hole that was observed 1 week after surgery. The hole did not close by in-office fluid-gas exchange alone, but was achieved after repeat surgery with internal limiting membrane (ILM peeling. Intraoperative OCT (iOCT images from the first surgery revealed an occult macular hole that formed after VMT release. We discuss how iOCT findings provide insight into the role of the ILM in macular hole formation and emphasize the importance of carefully inspecting iOCT images in real time to avoid missing small but important findings.


    Petrut-Florin Trofin


    Full Text Available The game of football enjoys high popularity worldwide and has undergone significant changes in terms of the players’ physical strain. This study seeks to analyze the differences that may occur at the level of the tractive force between two junior groups: one of 15-16 years (n = 21, 177.5 ± 5.98 cm height, body mass 68.53 ± 6.28 cm and one of 17-18 years (n = 24, 175.3 cm ± 8.27 height, 61.93 ± 8.61 cm body mass. The tractive force was measured with an Axis FB5k dynamometer, adapted to such an assessment by the various accessories. Four tractive forces were evaluated: forward, backward, left and right. We assumed that the values of the tractive force would be different between the two age groups. The highest values within each group were noticed in the case of the forward tractive force (62.63 ± 8.39 kgf of the 17-18 years old players and the right tractive force (58.51 ± 13.09 kgf of those 15-16 years. The hypothesis of the study was invalidated by statistically insignificant differences that have emerged in each measurement.

  17. 3 - Dimensional Body Measurement Technology

    ZHOU Xu-dong; LI Yan-mei


    3 - dimensional body measurement technology, the basis of developing high technology in industry, accelerates digital development of aplparel industry. This paper briefly introduces the history of 3 - dimensional body measurement technology, and recounts the principle and primary structure of some types of 3 - dimensional automatic body measurement system. With this understanding, it discusses prospect of 3- dimensional CAD and virtual technology used in apparel industry.

  18. [Traction maculopathies--pathogenesis and diagnostics].

    Wylegała, Edward; Woyna-Orlewicz, Anna; Piłat, Jarosław; Teper, Sławomir; Ludyga, Aneta


    Traction maculopathies are a group of age-related degenerative diseases characterized by pathology of vitreomacular interface including idiopathic epimacular membranes, vitreomacular traction syndrome and idiopathic macular hole. The disorders develop due to mechanical forces caused by focal condensation or incomplete detachement of vitreous and shrinkage of pathological membranes. The forces can be tangential to retinal surface in epiretinal membranes, anterior-posterior in vitreomacular traction syndrome and oblique (trampoline) in idiopathic macular hole. Authors discuss pathogenesis and diagnostics of traction maculopathies with use of optical coherence tomography and microperimetry, based on current literature. This work presents also idiopathic macular hole classification with use of optical coherence tomography images compared with biomicroscopic classification by Gass.


    WANG Yan-shuang; ZHANG Luo-ping; YANG Bo-yuan


    A ball-disc traction test rig is improved through the development of a lubricant traction measurement system,consisting of a resonance force sensitive quartz sensor,a circuit of the sensor and a rigid bracket jointed by a frictionless hinge.The traction coefficients of a kind of domestic lubricating oil were measured at various normal loads,rolling velocities,lubricant inlet temperatures and slide-to-roll ratios on a ball-disc traction test rig equipped with this traction measurement system.The results show that the traction test curve is smooth and the data enjoy a good accuracy,which indicates that the design of the lubricant traction measurement system is reasonable and the precision of the system is high,especially,at high temperature,high rolling speed and small slide-to-roll ratio.

  20. Follicular traction urticaria*

    Duman, Hatice; Topal, Ilteris Oguz; Kocaturk, Emek


    Inducible urticaria is a heterogeneous subgroup of chronic urticarias caused by a wide variety of environmental stimuli, such as exercise, cold, heat, pressure, sunlight, vibration, and water. A new term, follicular traction urticaria, was suggested as an unusual form of inducible urticarias. We report a patient who was diagnosed with follicular traction urticaria.

  1. Soybean biodiesel consumption in agricultural tractor submitted the two forces in the traction bar; Consumo de biodiesel de soja em trator agricola submetido a duas forcas na barra de tracao

    Camara, Felipe T. da [Universidade Federal do Ceara (UFC), Juazeiro do Norte, CE (Brazil)], E-mail:; Lopes, Afonso; Silva, Rouverson P. da; Oliveira, Melina C.J. de; Torres, Luma S. [Universidade Estadual Paulista (FCAV/UNESP), SP (Brazil). Fac. de Ciencias Agrarias e Veterinarias. Dept. de Engenharia Rural


    Due to the great development occurred in the world after the Second World War and the establishment of patterns of increasingly intense, the energy demand amounted to the point, putting at risk the non-renewable energy sources such as oil, coal minerals, among others, with growing interest in renewable energies, among which the biodiesel has been detached. In this sense, the present work had for objective to evaluate the fuel consumption of a tractor Valtra BM100 4x2 TDA, running with ethyl biodiesel from soybean filtered in seven mixture proportions mixed with the diesel, subject to two forces in the traction bar. The work was conducted in the Department of Rural Engineering of the Paulista State University (UNESP), Jaboticabal Campus, in an entirely randomized designed, in a factorial diagram 2 x 7, with three repetitions. The treatments were a combination for two forces in the traction bar (10 and 22 kN) and seven mixture proportions (B{sub 0}, B{sub 5}, B{sub 1}5, B{sub 2}5, B{sub 5}0, B{sub 7}5 e B{sub 1}00). The results showed that the addition of up to 25% biodiesel to diesel has not changed the fuel consumption, and the greatest force resulted in greater consumption volume and weight, and lower specific consumption, by better use of the power of the tractor. (author)

  2. 21 CFR 888.5890 - Noninvasive traction component.


    ... (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES Surgical Devices § 888.5890 Noninvasive traction component. (a... apparatus so that a therapeutic pulling force may be applied to the patient's body. (b)...

  3. The Discussing of Traction Force Calculation in Three Different Theory of Pressure Distributing%三种不同压力分布理论下的牵引力计算探讨

    强新伟; 武良臣; 李建华; 牛永生


    本文通过对三种不同压力分布(弹流润滑理论、赫兹理论、平均赫兹理论)下牵引力的MATLAB编程计算,探讨了赫兹理论、平均赫兹理论的精确程度,以及其各自的适用范围。%: In this paper, through the programming calculation of traction force with MATLAB in three different pressure distribution (EHL theory、 HZ theory、 MP theory), we discuss the precision degree of both HZ theory and MP theory, and their applying field respectively.

  4. Loads in the lumbar spine during traction therapy.

    Lee, R Y; Evans, J H


    The purpose of the present study was to determine the loads acting on the lumbar spine when traction therapy was given in the Fowler's position. The study had two parts: a theoretical analysis which showed that traction produced a flexion moment on the spine as well as axial distraction; and an experimental study which measured the flexion moment induced by the adoption of the Fowler's position. The Fowler's position is clinically essential in that it flexes the spine and takes up the slack of the posterior tissues before the traction force is applied. Hence the axial tension and flexion moment generated by the traction force are more effective in stretching the posterior tissues. The angle of pull on the traction harness influences the friction between the body and the couch. However, this consideration is not necessary if a split traction table is used. The mechanical effects of traction are compared with those produced by postero-anterior mobilisation. The relative magnitude and direction of loads produced, and their variation with segmental level should be considered by therapists when choosing a technique for treating low back pain.

  5. 3-Dimensional Response of Composites


    AFWAL-TR-88-4242 3-DIMENSIONAL RESPONSE OF COMPOSITES S.R. Soni S. Chandrashekara G.P. Tandon U. Santhosh Ten-Lu Hsiao CADTECH SYSTEMS RESEARCH INC...Composites 12. PERSONAL AUTHOR(S) S. R. Soni, S. Chandrashekara, G. P. Tandon, U. Santhosh , T. Isiao 13a. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF REPRT...Chandrashekara, G.P. Tandon; Mr. U. Santhosh and Mr. Ten-Lu Hsiao. Accesion For NTIS CRAWI DTIC TAB 13 Unaonou,)ced 0 JustfCdtf)In ...._ By .... Di~t ibut;01 I

  6. Implementation of Fleet Management in Train Traction

    Tomislav Josip Mlinarić


    Full Text Available The implementation of fleet management in the train tractionactivity is a must in the conditions of market operation ofthe railway sector, since good management of traction units hasnot alternative. The crucial issue of implementing such sophisticatedtools is in real environment, and therefore SWOT analysisof the most important technological indicators has been carriedout, in order to determine the most efficient method of itsimplementation. The defined technological indicators and therespective criteria have been used to evaluate the possible implementationof the total fleet management system in the HiVuca vlakova (Hi- Train Traction company. The pilot projectcarried out in the activities of the Hi- Train Traction hasresulted in great savings at the annual level in fuel consumption,creating also the preconditions for the savings in fleetmaintenance and work force recruitment. Based on the resultsof the pilot project the methodology for efficient implementationof fleet management was defined. The defined methodologywas tested in real conditions and can be implemented atany company which provides services of train traction or manoeuvringof locomotives.

  7. Trunk muscle response to various protocols of lumbar traction.

    Cholewicki, Jacek; Lee, Angela S; Reeves, N Peter; Calle, Elizabeth A


    The purpose of this study was to compare trunk muscle activity, spinal decompression force, and trunk flexibility resulting from various protocols of spinal traction. Four experiments explored the effects of (1) sinusoidal, triangular, square, and continuous distraction-force waveforms, (2) 0, 10, 20, and 30 degrees of pull angle, (3) superimposed low, medium and high frequency force oscillations, and (4) sham traction. Nineteen healthy subjects volunteered for this study. Surface EMG was recorded during traction and later used in a biomechanical model to estimate spine decompression force. Trunk flexibility was measured before and after each treatment. There were no differences in muscle activity between any of the experimental conditions except the thoracic erector spinae muscle, which had lower EMG during continuous compared to sinusoidal distraction-force waveform (p=0.02). Thoracic and lumbar erector spinae muscles were significantly less active during sham than real traction (p=0.01 and p=0.04, respectively). The estimated L4-L5 spine compression force was 25N. Trunk flexibility decreased after each experimental session (p=0.01), and there were no differences between sessions. Our results suggest that the trunk muscle activity is minimal and point toward fluid exchange in the disc as one of the key biomechanical effects of spinal traction.

  8. Disc-shaped LIM for levitation and traction force control powered by the source using the component synchronous with the motor speed

    Morizane Toshimitsu


    Full Text Available It has been proposed that a novel maglev transport system uses both of the attractive force and thrust force of the Linear Induction Motor (LIM. In our proposal, these two forces will be controlled by two different frequency components. One of the frequency components is synchronous with the motor speed (fm. Another frequency component is drive frequency (fd. Our proposed system enables the independent and simultaneous control of the attractive and thrust force of LIM. Each value of the attractive and the thrust force generated by fm and fd must be identified in order to design that LIM control system. For these purpose, a disc-shaped LIM has been developed as an experimental equipment. The force profiles, especially around zero slip, have been analyzed under experimental conditions.

  9. Three-Dimensional Reflectance Traction Microscopy.

    Jihan Kim

    Full Text Available Cells in three-dimensional (3D environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed 3D reflectance traction microscopy which combines confocal reflection imaging and partial volume correlation postprocessing. We have measured the deformation field of collagen gel under controlled mechanical stress. We have also characterized the deformation field generated by invasive breast cancer cells of different morphologies in 3D collagen matrix. In contrast to employ dispersed tracing particles or fluorescently-tagged matrix proteins, our methods provide a label-free, computationally effective strategy to study the cell mechanics in native 3D extracellular matrix.

  10. Vitreomacular traction syndrome

    Shao Lei; Wei Wenbin


    Objective This study aimed to review the available literature on vitreomacular traction (VMT) syndrome and propose the future study prospect in this field.Data sources The data used in this review were mainly obtained from articles listed in Medline and Pubmed (1970-2013).The search terms were "vitreomacular traction," "optical coherence tomography," "vitrectomy," and "ocriplasmin."Study selection Articles regarding the pathophysiology,diagnosis,and treatments of VMT were selected and reviewed.Results VMT syndrome is a persistent attachment of vitreous to the macula in eyes with an incomplete posterior vitreous detachment and considered to be an uncommon status which correlated with some other macular disorders.Optical coherence tomography (OCT) can support a new way to examine and classify VMT.Nonoperative and operative intervenes on this disease have been developed recently,especially the intravitreal medical therapy.Conclusions VMT syndrome may be associated with various disorders in the macular region,depending in part on the size and strength of the residual vitreomacular adhesion.Regular OCT monitoring is recommended to detect it.Patients with asymptomatic VMT should be observed for at least 2-3 months; nonoperative treatment with ocriplasmin should be considered when disorders persist; surgery is recommended if VMT-related disease is significant.

  11. Vitreomacular Traction Syndrome

    Juliana Bottós


    Full Text Available The advent of new technologies such as high definition optical coherence tomography (OCT has not only provided unprecedented imaging capabilities, but also raised the need to define concepts not yet settled and often confusing such as the vitreomacular traction (VMT syndrome. While technological advances drive us into the future by clarifying the pathophysiology of many diseases and enabling novel therapeutic options, it is at the same time necessary to review basic disease concepts in addition to definitions and classifications. VMT syndrome is implicated in the pathophysiology of a number of macular disorders, translating into a variety of anatomical and functional consequences underscoring the complexity of the condition. These macular changes are closely related to the VMT configuration and have led to proposing classification of this syndrome based on OCT findings. The size and severity of the remaining vitreomacular attachment may define the specific maculopathy. Focal VMT usually leads to macular hole formation, tractional cystoid macular edema and foveal retinal detachment, while broad VMT is associated with epiretinal membranes, diffuse retinal thickening and impaired foveal depression recovery. Despite similar postoperative visual acuity (VA in focal and broad VMT subgroups, visual improvement is greater with focal VMT because preoperative VA is frequently lower. Surgical procedures are effective to relieve VMT and improve VA in most eyes; outcomes vary with VMT morphology and the duration of symptoms.

  12. Advanced Integrated Traction System

    Greg Smith; Charles Gough


    The United States Department of Energy elaborates the compelling need for a commercialized competitively priced electric traction drive system to proliferate the acceptance of HEVs, PHEVs, and FCVs in the market. The desired end result is a technically and commercially verified integrated ETS (Electric Traction System) product design that can be manufactured and distributed through a broad network of competitive suppliers to all auto manufacturers. The objectives of this FCVT program are to develop advanced technologies for an integrated ETS capable of 55kW peak power for 18 seconds and 30kW of continuous power. Additionally, to accommodate a variety of automotive platforms the ETS design should be scalable to 120kW peak power for 18 seconds and 65kW of continuous power. The ETS (exclusive of the DC/DC Converter) is to cost no more than $660 (55kW at $12/kW) to produce in quantities of 100,000 units per year, should have a total weight less than 46kg, and have a volume less than 16 liters. The cost target for the optional Bi-Directional DC/DC Converter is $375. The goal is to achieve these targets with the use of engine coolant at a nominal temperature of 105C. The system efficiency should exceed 90% at 20% of rated torque over 10% to 100% of maximum speed. The nominal operating system voltage is to be 325V, with consideration for higher voltages. This project investigated a wide range of technologies, including ETS topologies, components, and interconnects. Each technology and its validity for automotive use were verified and then these technologies were integrated into a high temperature ETS design that would support a wide variety of applications (fuel cell, hybrids, electrics, and plug-ins). This ETS met all the DOE 2010 objectives of cost, weight, volume and efficiency, and the specific power and power density 2015 objectives. Additionally a bi-directional converter was developed that provides charging and electric power take-off which is the first step

  13. Ultrahigh Resolution 3-Dimensional Imaging Project

    National Aeronautics and Space Administration — Southwest Sciences proposes to develop innovative instrumentation for the rapid, 3-dimensional imaging of biological tissues with cellular resolution. Our approach...

  14. Traction reveals mechanisms of wall effects for microswimmers near boundaries

    Shen, Xinhui; Marcos, Fu, Henry C.


    The influence of a plane boundary on low-Reynolds-number swimmers has frequently been studied using image systems for flow singularities. However, the boundary effect can also be expressed using a boundary integral representation over the traction on the boundary. We show that examining the traction pattern on the boundary caused by a swimmer can yield physical insights into determining when far-field multipole models are accurate. We investigate the swimming velocities and the traction of a three-sphere swimmer initially placed parallel to an infinite planar wall. In the far field, the instantaneous effect of the wall on the swimmer is well approximated by that of a multipole expansion consisting of a force dipole and a force quadrupole. On the other hand, the swimmer close to the wall must be described by a system of singularities reflecting its internal structure. We show that these limits and the transition between them can be independently identified by examining the traction pattern on the wall, either using a quantitative correlation coefficient or by visual inspection. Last, we find that for nonconstant propulsion, correlations between swimming stroke motions and internal positions are important and not captured by time-averaged traction on the wall, indicating that care must be taken when applying multipole expansions to study boundary effects in cases of nonconstant propulsion.

  15. Dynamics of Wire Rope and Pulley System, Amendments on the Computational Formula of Traction Force in Appendix M, EN81-1:1998%钢丝绳及滑轮系统动力学——GB 7588-2003附录M的曳引力计算公式更正



    The author discussed the calculation of traction force for lift system consist of complex pulley and steel reeving. By two quite other derivation methods it is proved that the formula delivered in M.3, Annex M, EN81-1:1998 is full of prunes, not only the masses of suspension rope and the moments of inertia of suspension pulley, but also the moments of inertia of pulley for tension device, the convert dynamic force are out in their reckoning completely. Further more, the author pointed out some nonstandard formats for mathematical expression, and ultimately gave out a universal formula, it can be applied for any reeving rate.

  16. Design on Buffer Structure of Traction Running with a Constant Speed

    Zeng Xianren


    Full Text Available This study mainly aims to study buffer structure design on the traction transport system when the traction transport boundary conditions are given. With such conditions as the maximum impact force, traction speed, maximum speed of alluvium, the elasticity coefficient and the mass of buffer structure, a mathematical model was established and the solution of differential equations was solved. At last, a program was compiled with MATLAB language. With this program the elasticity coefficient and the maximum impact force which meet the requirements in impact process can be solved as long as the boundary conditions are input. This provides a quick design basis of buffer structure for most mechanical engineers.

  17. 牵引式无级变速器牵引效率研究%Study of traction efficiency on traction type continuously variahle transmission



    By taking the traction type continuously variable transmission as the study object. Some analytic expressions for angular speed of spin, traction force caused by oil film sliding and moment generated by spinning are derived. By means of a real example, the changing regularity among traction efficiency and contact pressure, traction force of oil film, input rotation speed and geometric curvature ratio was calculated and analyzed.%以牵引式无级变速器为研究对象,推导出了自转角速度、由油膜滑动产生的牵引力和由自转产生的力矩等解析式.通过实例,计算和分析了牵引效率与接触压力、油膜牵引力、输入转速和几何曲率比等因素间的变化规律.

  18. Effects of intermittent traction therapy in an experimental spinal column model.

    Shin, Jeong-Hun; Jun, Seung-lyul; Lee, Young-Jun; Kim, Jae-Hyo; Hwang, Sung-Yeoun; Ahn, Seong-Hun


    Traction therapy, which is known to be a treatment method for scoliosis, one of many muscles disease, has been used since Hippocrates introduced it. However, the effects of traction therapy are still not clear. In addition, the meridian sinew theory, which is related to muscle treatment and is mentioned in the book on meridian sinews in the Miraculous Pivot of Huangdi's Internal Classic, has not been the subject of much study. For these reasons, experimental spinal models were made for this study to observe and analyze the lengths of vertebral interspaces after intermittent traction therapy, which is known to be excellent among muscle treatment methods, with various tensile forces. The results showed that the effects of intermittent traction therapy were unclear and that it might be harmful, especially when the pain was induced by muscle weakness. Because the results of this study on intermittent traction therapy were different from those expected from osteopathy or craniosacral theory, better studies of the subject are necessary.

  19. Primary 3-dimensional culture of mouse hepatocytes


    Complex 3-dimensional structures with good functions have been obtained under the primary mixcoculture of mouse hepatocytes with mouse liver fibroblasts without serum. Albumin secretion is kept above 10 μg/106 cells and urea synthesis reaches 25 μg/106 on the 7th day of culture. Avoiding serum affection, liver fibroblasts' effects on hepatocytes' viability, functions and 3-dimensional structure forming in primary serum-free culture have been studied. Important effects of the mesenchyma, especially the direct adherence of fibroblasts to hepatocytes, are shown.

  20. Properties of 3-dimensional line location models

    Brimberg, Jack; Juel, Henrik; Schöbel, Anita


    We consider the problem of locating a line with respect to some existing facilities in 3-dimensional space, such that the sum of weighted distances between the line and the facilities is minimized. Measuring distance using the l\\_p norm is discussed, along with the special cases of Euclidean...

  1. Traction of Pneumatic Tires on Wet Runways

    Horne, Walter B.; Joyner, Upshur T.


    Recent work on the traction of pneumatic tires on wet runways is discussed, and it is shown that a loss of tire traction adversely affects cross-wind landings. The effect of runway surface texture is discussed,, and a simple method for measuring surface texture is described. A preliminary correlation of tire traction with surface texture is shown. Results of work at Langley Research Center on the use of air jets to improve tire traction on wet or flooded runways indicate that this is a promising approach for alleviating the large losses in tire braking and sideways traction that occur when tire hydroplaning occurs on a flooded runway.

  2. Effect of intermittent, supine cervical traction on the myoelectric activity of the upper trapezius muscle in subjects with neck pain.

    Jette, D U; Falkel, J E; Trombly, C


    This study was undertaken to compare the myoelectric activity of the upper trapezius muscle before, during, and after intermittent, supine cervical traction. Twelve people with diagnosed disease or injury of the cervical spine served as subjects. Electromyographic recordings were taken from the upper trapezius muscle with bipolar surface electrodes. The subjects were treated with 20 minutes of intermittent, cervical traction at a force of 8% of their body weight. Recordings were taken with the subjects in the supine position before the traction, during one pull and release phase of the 10th and 20th minutes of traction, and after completion of the traction treatment. An analysis of variance with repeated measures showed no significant differences in the myoelectrical activity during the six time periods measured. The results of this study do not support the clinical use of intermittent, supine traction to produce cervical muscle relaxation.

  3. Lumbar spine traction: evaluation of effects and recommended application for treatment.

    Krause, M; Refshauge, K M; Dessen, M; Boland, R


    Despite the widespread use of traction, little is known of the mode of effect, and application remains largely anecdotal. The efficacy of traction is also unclear because of generally poor design of the clinical trials to date, and because subgroups of patients most likely to benefit have not been specifically studied. These observations prompted this review, the purposes of which are to evaluate the mechanisms by which traction may provide benefit and to provide rational guidelines for the clinical application of traction. Traction has been shown to separate the vertebrae and it appears that large forces are not required. Vertebral separation could provide relief from radicular symptoms by removing direct pressure or contact forces from sensitised neural tissue. Other mechanisms proposed to explain the effects of traction (e.g. reduction of disc protrusion or altered intradiscal pressure) have been shown not to occur. We conclude that traction is most likely to benefit patients with acute (less than 6 weeks' duration) radicular pain with concomitant neurological deficit. The apparent lack of a dose-response relationship suggests that low doses are probably sufficient to achieve benefit.

  4. Counter traction makes endoscopic submucosal dissection easier.

    Oyama, Tsuneo


    Poor counter traction and poor field of vision make endoscopic submucosal dissection (ESD) difficult. Good counter traction allows dissections to be performed more quickly and safely. Position change, which utilizes gravity, is the simplest method to create a clear field of vision. It is useful especially for esophageal and colon ESD. The second easiest method is clip with line method. Counter traction made by clip with line accomplishes the creation of a clear field of vision and suitable counter traction thereby making ESD more efficient and safe. The author published this method in 2002. The name ESD was not established in those days; the name cutting endoscopic mucosal resection (EMR) or EMR with hook knife was used. The other traction methods such as external grasping forceps, internal traction, double channel scope, and double scopes method are introduced in this paper. A good strategy for creating counter traction makes ESD easier.

  5. Control of Grasp and Manipulation by Soft Fingers with 3-Dimensional Deformation

    Nakashima, Akira; Shibata, Takeshi; Hayakawa, Yoshikazu

    In this paper, we consider control of grasp and manipulation of an object in a 3-dimensional space by a 3-fingered hand robot with soft finger tips. We firstly propose a 3-dimensional deformation model of a hemispherical soft finger tip and verify its relevance by experimental data. Second, we consider the contact kinematics and derive the dynamical equations of the fingers and the object where the 3-dimensional deformation is considered. For the system, we thirdly propose a method to regulate the object and the internal force with the information of the hand, the object and the deformation. A simulation result is presented to show the effectiveness of the control method.

  6. Plica neuropathica causing traction alopecia

    Pavithran K


    Full Text Available A middle aged woman developed matting of the hairs of the scalp following use of a home made shampoo that contained leaves of Hibiscus rosasiensis. The entangled and matted hair mass in the occipital region pulled hairs of the vertex region of the scalp, resulting in a patch of traction alopecia. Release of tension on the hairs by cutting them with scissors prevented further extension of alopecia.

  7. Periodic traction in migrating large amoeba of Physarum polycephalum.

    Rieu, Jean-Paul; Delanoë-Ayari, Hélène; Takagi, Seiji; Tanaka, Yoshimi; Nakagaki, Toshiyuki


    The slime mould Physarum polycephalum is a giant multinucleated cell exhibiting well-known Ca(2+)-dependent actomyosin contractions of its vein network driving the so-called cytoplasmic shuttle streaming. Its actomyosin network forms both a filamentous cortical layer and large fibrils. In order to understand the role of each structure in the locomotory activity, we performed birefringence observations and traction force microscopy on excised fragments of Physarum. After several hours, these microplasmodia adopt three main morphologies: flat motile amoeba, chain types with round contractile heads connected by tubes and motile hybrid types. Each type exhibits oscillations with a period of about 1.5 min of cell area, traction forces and fibril activity (retardance) when fibrils are present. The amoeboid types show only peripheral forces while the chain types present a never-reported force pattern with contractile rings far from the cell boundary under the spherical heads. Forces are mostly transmitted where the actomyosin cortical layer anchors to the substratum, but fibrils maintain highly invaginated structures and contribute to forces by increasing the length of the anchorage line. Microplasmodia are motile only when there is an asymmetry in the shape and/or the force distribution.

  8. Traction Stresses and Translational Distortion of the Nucleus During Fibroblast Migration on a Physiologically Relevant ECM Mimic

    Pan, Zhi; Ghosh, Kaustabh; Liu, Yajie; Clark, Richard A.F.; Rafailovich, Miriam H.


    Cellular traction forces, resulting in cell-substrate physical interactions, are generated by actin-myosin complexes and transmitted to the extracellular matrix through focal adhesions. These processes are highly dynamic under physiological conditions and modulate cell migration. To better understand the precise dynamics of cell migration, we measured the spatiotemporal redistribution of cellular traction stresses (force per area) during fibroblast migration at a submicron level and correlated it with nuclear translocation, an indicator of cell migration, on a physiologically relevant extracellular matrix mimic. We found that nuclear translocation occurred in pulses whose magnitude was larger on the low ligand density surfaces than on the high ligand density surfaces. Large nuclear translocations only occurred on low ligand density surfaces when the rear traction stresses completely relocated to a posterior nuclear location, whereas such relocation took much longer time on high ligand density surfaces, probably due to the greater magnitude of traction stresses. Nuclear distortion was also observed as the traction stresses redistributed. Our results suggest that the reinforcement of the traction stresses around the nucleus as well as the relaxation of nuclear deformation are critical steps during fibroblast migration, serving as a speed regulator, which must be considered in any dynamic molecular reconstruction model of tissue cell migration. A traction gradient foreshortening model was proposed to explain how the relocation of rear traction stresses leads to pulsed fibroblast migration. PMID:19450499


    Phuong Le Ngo


    Full Text Available The traction characteristic of an electric vehicle is the main characteristic of mechanical system that reflects its key performance indicators. Implementation of the traction characteristic is based on controlling angular speed and torque of electric traction motor in an automatic control system. The static mechanical characteristic of an electric traction motor in an automatic control system is the most important characteristic that determines weight, size and operating characteristics of an electric traction motor and serves as the basis for design. The most common variants of constructive implementation of a traction electric drive are analyzed, and a scheme is chosen for further design. Lagrange’s equation for electric mechanical system with one degree of freedom is written in generalized coordinates. In order to determine the generalized forces, elementary operation of all moments influencing on a moving car has been calculated. The resulting equation of motion of the electric vehicle corresponding to the design scheme, as well as the expressions for calculation of characteristic points of static mechanical characteristics of traction motor (i.e. the maximum and minimum time, minimum power are obtained. In order to determine the nominal values of the angular velocity and the power of electric traction motor, a method based on ensuring the movement of the vehicle in the standard cycle has been developed. The method makes it possible to calculate characteristic points of the mechanical characteristic with the lowest possible power rating. The algorithm for calculation of mechanical characteristics of the motor is presented. The method was applied to calculate static mechanical characteristic of an electric traction motor for a small urban electric truck.

  10. Traction Control System for Motorcycles

    Massimo Conti


    Full Text Available Traction control is a widely used control system to increase stability and safety of four wheel vehicles. Automatic stability control is used in the BMW K1200R motorcycle and in motoGP competition, but not in other motorcycles. This paper presents an algorithm and a low-cost real-time hardware implementation for motorcycles. A prototype has been developed, applied on a commercial motorcycle, and tested in a real track. The control system that can be tuned by the driver during the race has been appreciated by the test driver.

  11. Traction Stresses and Translational Distortion of the Nucleus During Fibroblast Migration on a Physiologically Relevant ECM Mimic

    Pan, Zhi; Ghosh, Kaustabh; Liu, Yajie; Clark, Richard A.F.; Rafailovich, Miriam H.


    Cellular traction forces, resulting in cell-substrate physical interactions, are generated by actin-myosin complexes and transmitted to the extracellular matrix through focal adhesions. These processes are highly dynamic under physiological conditions and modulate cell migration. To better understand the precise dynamics of cell migration, we measured the spatiotemporal redistribution of cellular traction stresses (force per area) during fibroblast migration at a submicron level and correlate...

  12. 牵引并电脑中频治疗颈性眩晕的疗效分析%Analysis of efficacy of traction plus computer middle frequency on cervical vertigo



    Objective We investigate the mechanism of comprehensive management in the treatment of cervical vertigo through treating 15 patients with cervical vertigo by cervical traction plus computer middle frequency machine.Method Sedentary jaw occiput traction band was used.Traction was regulated individually.Traction angle was determined according to patients' force line. Multifunctional computer machine K88 32 I was used after traction.Result 10 cases were cured completely,4 were improved,1 showed no any improvement.Conclusion cervical traction can increase space between cervical spine and uncinate cervical joint,relieve congestion and edema,improved compressed vertebral artery and distorted artery.Based on traction,computer middle frequency reinforces therapeutic effects of traction and produces cooperated effects.

  13. Elastohydrodynamic Traction Properties of Seed Oils

    The elastohydrodynamic traction coefficient (tc) properties of nine seed oils of varying chemical structures, PAO and hexadecane, were investigated using a ball-on disk traction apparatus. The seed oils were: castor oil, a triglyceride with hydroxyl functional group; jojoba, a monoglyceride; and s...

  14. Elastohydrodynamic (EHD) traction properties of seed oils

    The elastohydrodynamic traction coefficient (tc) properties of nine seed oils of varying chemical structures, PAO and hexadecane, were investigated using a ball-on disk traction apparatus. The seed oils were: castor oil, a triglyceride with hydroxyl functional group; jojoba, a monoglyceride; and sev...

  15. A dilogarithmic 3-dimensional Ising tetrahedron

    Broadhurst, D J


    In 3 dimensions, the Ising model is in the same universality class as unknown analytical nature. In contrast, all single-scale 4-dimensional tetrahedra were reduced, in hep-th/9803091, to special values of exponentially convergent polylogarithms. Combining dispersion relations with the integer-relation finder PSLQ, we find that $C^{Tet}/2^{5/2} = Cl_2(4\\alpha) - Cl_2(2\\alpha)$, with $Cl_2(\\theta):=\\sum_{n>0}\\sin(n\\theta)/n^2$ and 1,000-digit precision and readily yields 50,000 digits of $C^{Tet}$, after transformation to an exponentially convergent sum, akin to those studied in math.CA/9803067. It appears that this 3-dimensional result entails a polylogarithmic ladder beginning with the classical formula for $\\pi/\\sqrt2$, in the manner that 4-dimensional results build on that for $\\pi/\\sqrt3$.

  16. Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats Estudo comparativo da resistência de ruptura de cólon descendente por meio de ensaio uniaxial força de ruptura à tração e energia total de ruptura em ratos

    Feng Chung Wu


    Full Text Available PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study. For each one of the specimens, total energy of rupture and traction force of rupture necessary to promote colic wall burst were evaluated through the biomechanical total energy of rupture test using the Biomechanical Data Acquisition and Analysis System, version 2.0. Average, standard deviation, standard error of average and coefficient of variation were considered for analysis of results. RESULTS: Traction force of rupture average, standard deviation, standard error of average and coefficient of variation were 380.05 gf, 98.74, 28.5 e 25.98%, respectively while total energy of rupture presented average of 244.85 gf, standard deviation of 57.76, standard error of average of 16.67 and coefficient of variation of 23.59. CONCLUSION: Although, total energy of rupture considered a larger number of attributes to its calculation related to non-linear viscoelastic materials, such as colic wall, it presented a smaller coefficient of variation when compared to traction force of rupture, thus demonstrating to constitute a possible parameter to analyze intestinal resistance of rats.OBJETIVO: Comparação das grandezas físicas Energia Total de Ruptura e Força de Ruptura à Tração no estudo da resistência de ruptura do cólon descendente de ratos. MÉTODOS: Doze segmentos de cólon descendente de ratos foram utilizados como corpos de prova. Por meio do Teste Biomecânico Energia Total de Ruptura, obteve-se, de cada espécime, a Força de Ruptura à Tração e a Energia Total de Ruptura necessárias para promover o rompimento da parede cólica. Com esses valores, calculou-se a média, o desvio padrão, o erro padrão e o coeficiente de variação, sendo esse último atributo usado para a comparação das grandezas f

  17. Hexad Preons and Emergent Gravity in 3-dimensional Complex Spacetime

    Wang, Shun-Zhi


    We suggest that at high energy each space dimension has their own time dimension, forming a 3-dimensional complex spacetime. Based on this hypothesis, we propose that the primordial universe is made of six fundamental fermions and their complex conjugate states. These fermions are called Hexad Preons which carry hypercolor degree of freedom transforming under $U(3,3)$ gauge group. The Hermitian metric emerges upon the breakdown of the gauge group from $U(3,3)$ to its maximal compact subgroup $U(3)\\otimes U(3)$. Leptons, quarks, as well as other matter states may be formed from the subsequent condensate of Hexad Preons. Strong and electroweak forces are manifestations of the hypercolor interaction in the corresponding cases. Our framework sheds light on many problems in cosmology and particle physics.


    LOX Wouter


    Full Text Available Nowadays natural products interest has increased. However, when some products are included on textile fibers, they have no affinity and need some binders or other kind of auxiliaries to improve the yeld of the process, and some of them are not so natural as the product which are binding and consequently the “bio” definition is missed as some of them can be considered as highly pollutant. Chitosan is a common used bonding agent for cotton. It improves the antimicrobial and antifungal activity, improves wound healing and is a non-toxic bonding agent. The biopolymer used in this work is chitosan, which is a deacetylated derivative of chitin. These properties depend on the amount of deacetylation (DD and the Molecular weight (MW. Along with these improving properties, as it requires some acid pH to ve solved the treatment with chitosan can have some decreasing mechanical properties. The aim of that paper is to evaluate the change in breaking force of the treated samples and a change in elongation of those samples. It compared different amounts of concentration of chitosan with non treated cotton. The traction resistance test were performed on a dynamometer. The test was conducted according to the UNE EN ISO 13934-1 standard.

  19. Performance Analysis of 3-Dimensional Turbo Codes

    Rosnes, Eirik


    In this work, we consider the minimum distance properties and convergence thresholds of 3-dimensional turbo codes (3D-TCs), recently introduced by Berrou et al.. Here, we consider binary 3D-TCs while the original work of Berrou et al. considered double-binary codes. In the first part of the paper, the minimum distance properties are analyzed from an ensemble perspective, both in the finite-length regime and in the asymptotic case of large block lengths. In particular, we analyze the asymptotic weight distribution of 3D-TCs and show numerically that their typical minimum distance dmin may, depending on the specific parameters, asymptotically grow linearly with the block length, i.e., the 3D-TC ensemble is asymptotically good for some parameters. In the second part of the paper, we derive some useful upper bounds on the dmin when using quadratic permutation polynomial (QPP) interleavers with a quadratic inverse. Furthermore, we give examples of interleaver lengths where an upper bound appears to be tight. The b...

  20. Modern Electric Traction of Skoda Plzen Vehicles Modern Electric Traction of Skoda Plzen Vehicles

    Jiri Drabek


    Full Text Available The electric traction vehicle producting plant SKODA Plzen - Transportations develops and produces electric traction drives with the top technological niveau. Electric vehicles are delivered to transport institutions in Czech Republic as well as abroad. Many Ma, and PhD. graduates of the University of Zilina take part in this successful activity.The electric traction vehicle producting plant SKODA Plzen - Transportations develops and produces electric traction drives with the top technological niveau. Electric vehicles are delivered to transport institutions in Czech Republic as well as abroad. Many Ma, and PhD. graduates of the University of Zilina take part in this successful activity.

  1. Cardiothoracic Applications of 3-dimensional Printing.

    Giannopoulos, Andreas A; Steigner, Michael L; George, Elizabeth; Barile, Maria; Hunsaker, Andetta R; Rybicki, Frank J; Mitsouras, Dimitris


    Medical 3-dimensional (3D) printing is emerging as a clinically relevant imaging tool in directing preoperative and intraoperative planning in many surgical specialties and will therefore likely lead to interdisciplinary collaboration between engineers, radiologists, and surgeons. Data from standard imaging modalities such as computed tomography, magnetic resonance imaging, echocardiography, and rotational angiography can be used to fabricate life-sized models of human anatomy and pathology, as well as patient-specific implants and surgical guides. Cardiovascular 3D-printed models can improve diagnosis and allow for advanced preoperative planning. The majority of applications reported involve congenital heart diseases and valvular and great vessels pathologies. Printed models are suitable for planning both surgical and minimally invasive procedures. Added value has been reported toward improving outcomes, minimizing perioperative risk, and developing new procedures such as transcatheter mitral valve replacements. Similarly, thoracic surgeons are using 3D printing to assess invasion of vital structures by tumors and to assist in diagnosis and treatment of upper and lower airway diseases. Anatomic models enable surgeons to assimilate information more quickly than image review, choose the optimal surgical approach, and achieve surgery in a shorter time. Patient-specific 3D-printed implants are beginning to appear and may have significant impact on cosmetic and life-saving procedures in the future. In summary, cardiothoracic 3D printing is rapidly evolving and may be a potential game-changer for surgeons. The imager who is equipped with the tools to apply this new imaging science to cardiothoracic care is thus ideally positioned to innovate in this new emerging imaging modality.

  2. Incorporating 3-dimensional models in online articles

    Cevidanes, Lucia H. S.; Ruellasa, Antonio C. O.; Jomier, Julien; Nguyen, Tung; Pieper, Steve; Budin, Francois; Styner, Martin; Paniagua, Beatriz


    Introduction The aims of this article were to introduce the capability to view and interact with 3-dimensional (3D) surface models in online publications, and to describe how to prepare surface models for such online 3D visualizations. Methods Three-dimensional image analysis methods include image acquisition, construction of surface models, registration in a common coordinate system, visualization of overlays, and quantification of changes. Cone-beam computed tomography scans were acquired as volumetric images that can be visualized as 3D projected images or used to construct polygonal meshes or surfaces of specific anatomic structures of interest. The anatomic structures of interest in the scans can be labeled with color (3D volumetric label maps), and then the scans are registered in a common coordinate system using a target region as the reference. The registered 3D volumetric label maps can be saved in .obj, .ply, .stl, or .vtk file formats and used for overlays, quantification of differences in each of the 3 planes of space, or color-coded graphic displays of 3D surface distances. Results All registered 3D surface models in this study were saved in .vtk file format and loaded in the Elsevier 3D viewer. In this study, we describe possible ways to visualize the surface models constructed from cone-beam computed tomography images using 2D and 3D figures. The 3D surface models are available in the article’s online version for viewing and downloading using the reader’s software of choice. These 3D graphic displays are represented in the print version as 2D snapshots. Overlays and color-coded distance maps can be displayed using the reader’s software of choice, allowing graphic assessment of the location and direction of changes or morphologic differences relative to the structure of reference. The interpretation of 3D overlays and quantitative color-coded maps requires basic knowledge of 3D image analysis. Conclusions When submitting manuscripts, authors can

  3. Changes in joint space width during Kaltenborn traction according to traction grade in healthy adults.

    Moon, Gui-do; Kim, Tae-Ho; Lim, Jin-Yong


    [Purpose] The aim of this study was to analyze the joint space width of the humeral head and glenoid fossa during traction under 2 grade conditions (grade 2/grade 3). [Subjects and Methods] The subjects were 20 healthy male adults who had not experienced any shoulder injury. Three radiographs were obtained with the subjects in the supine position (resting, grades 2 and 3). The glenohumeral joint space was examined on radiography. Joint space width was measured by a radiologist at the points described by Petersson and Redlund-Johnell. A radiologist blinded to the variable "resting" or "traction" performed all radiographic measurements. The joint space widths were compared by using one-way repeated-measures analysis of variance. [Results] The results of this study indicated significant differences in the changes in joint space width according to traction grade. Compared to resting, grades 2 and 3 traction significantly increased joint space width. However, no significant difference in joint space width was found between grades 2 and 3 traction. [Conclusion] Although no significant differences were found between grades 2 and 3 traction during glenohumeral joint traction, the increase in joint space width between the glenoid fossa and humeral head was highest during grade 3 traction.

  4. Optimization of 3-dimensional imaging of the breast region with 3-dimensional laser scanners.

    Kovacs, Laszlo; Yassouridis, Alexander; Zimmermann, Alexander; Brockmann, Gernot; Wöhnl, Antonia; Blaschke, Matthias; Eder, Maximilian; Schwenzer-Zimmerer, Katja; Rosenberg, Robert; Papadopulos, Nikolaos A; Biemer, Edgar


    The anatomic conditions of the female breast require imaging the breast region 3-dimensionally in a normal standing position for quality assurance and for surgery planning or surgery simulation. The goal of this work was to optimize the imaging technology for the mammary region with a 3-dimensional (3D) laser scanner, to evaluate the precision and accuracy of the method, and to allow optimum data reproducibility. Avoiding the influence of biotic factors, such as mobility, we tested the most favorable imaging technology on dummy models for scanner-related factors such as the scanner position in comparison with the torso and the number of scanners and single shots. The influence of different factors of the breast region, such as different breast shapes or premarking of anatomic landmarks, was also first investigated on dummies. The findings from the dummy models were then compared with investigations on test persons, and the accuracy of measurements on the virtual models was compared with a coincidence analysis of the manually measured values. The best precision and accuracy of breast region measurements were achieved when landmarks were marked before taking the shots and when shots at 30 degrees left and 30 degrees right, relative to the sagittal line, were taken with 2 connected scanners mounted with a +10-degree upward angle. However, the precision of the measurements on test persons was significantly lower than those measured on dummies. Our findings show that the correct settings for 3D imaging of the breast region with a laser scanner can achieve an acceptable degree of accuracy and reproducibility.

  5. Posterior lip traction caused by intravitreal gas

    Lincoff, H.; Kreissig, I.


    Traction on the posterior edge of a large tear may be an irreparable consequence of an intraocular gas tamponade used in the first instance to treat the tear. In two of three patients treated with octofluorocyclobutane (C4F8) and perfluoromethane (CF4), redetachment of a retinal tear occurred as a result of traction on the posterior edge of the tear when, prior to the operation, the posterior edge seemed to be free of any traction. With redetachment, a membrane became visible between the anterior and posterior lips of the tear. The membrane was probably posterior hyaloid augmented by cellular proliferation. The gas bubble, which had been intended to press the retina against the pigment epithelium, probably brought the detached posterior hyaloid into contact with the retina as well, and an adhesion between the hyaloid and retina formed.

  6. Force

    Graybill, George


    Forces are at work all around us. Discover what a force is, and different kinds of forces that work on contact and at a distance. We use simple language and vocabulary to make this invisible world easy for students to ""see"" and understand. Examine how forces ""add up"" to create the total force on an object, and reinforce concepts and extend learning with sample problems.

  7. Experimental evaluation of 3-dimensional kinematic behavior of the cruciate ligaments


    PURPOSE: The purpose of this study was to evaluate a low-cost and easily reproducible technique for biomechanical studies in cadavers. In this kind of study, the natural effect of loading of the joint and shear forces are not taken into account. The objective is to describe the plastic deformation of the ligaments into 3-dimensional space. METHOD: For 18 intact human cadaver knees, the cruciate ligaments were divided into 3 fiber bundles, the tibial or femoral fixation points were marked, and...

  8. Analysis of 3-dimensional finite element after reconstruction of impaired ankle deltoid ligament

    Ji, Yunhan; Tang, Xianzhong; Li, Yifan; Xu, Wei; Qiu, Wenjun


    We compared four repair techniques for impaired ankle ligament deltoideum, namely Wiltberger, Deland, Kitaoka and Hintermann using a 3-dimensional finite element. We built an ankle ligament deltoideum model, including six pieces of bone structures, gristles and main ligaments around the ankle. After testing the model, we built an impaired ligament deltoideum model plus four reconstruction models. Subsequently, different levels of force on ankles with different flexion were imposed and ankle b...

  9. "The effect of halo traction between anterior and posterior spinal fusion on the correction of scoliosis "

    Behtash H


    Full Text Available Background: The currently accepted treatment of scoliosis are bracing and surgery. Two-stage anterior and posterior spinal fusion is used to correct scoliosis. It seems that the application of a longitudinal force to the axis of the spinal column as a means of stabilizing by halo traction, may increase the correction of the curve. The aim of this study was to evaluate the effect of halo traction used between the two stages of corrective surgery, anterior and posterior spinal fusion, on the correction of scoliosis curvature. Methods: In this randomized clinical trial twelve scoliotic patients, aged from 12-19 years old, were treated by two-stage anterior spinal release and fusion (ASF and posterior spinal fusion (PSF. The patients were divided in two groups: 6 scoliotic patients without any traction between ASF and PSF surgeries (group A, and 6 scoliotic patients were undergone halo traction for one week between ASF and PSF surgeries (group B. Major curve angle was measured before surgery, one week after ASF and one year after PSF surgeries. Data were collected and analyzed using SPSS v.13.5. Results: The mean baseline curve angles were 90° (SD=18.70 and 94.17°(SD=28.18 in groups A and B, respectively. Whereas, the mean final curve angles (one year after PSF were 51.17°(SD=29.59 and 39.17°(23.11 in groups A and B, respectively. Final angle improvement was 46.58% (SD=20.31 in patients without traction and 61.32% (SD=14.02 in patients with halo traction. The major curve angles showed significantly better correction in patients with traction one week after ASF [38.67°(SD=7.86 vs. 25°(SD=6.28, P=0.012]. This difference persisted at the end of the first year after operation. [55°(SD=8.94 vs. 38.83°(SD=11.65, P=0.022]. Conclusion: Application of halo traction between ASF and PSF surgeries may lead to better improvement of the scoliotic curvature and short time application of halo traction decreases possible complications.

  10. Facial nerve paralysis after cervical traction.

    So, Edmund Cheung


    Cervical traction is a frequently used treatment in rehabilitation clinics for cervical spine problems. This modality works, in principle, by decompressing the spinal cord or its nerve roots by applying traction on the cervical spine through a harness placed over the mandible (Olivero et al., Neurosurg Focus 2002;12:ECP1). Previous reports on treatment complications include lumbar radicular discomfort, muscle injury, neck soreness, and posttraction pain (LaBan et al., Arch Phys Med Rehabil 1992;73:295-6; Lee et al., J Biomech Eng 1996;118:597-600). Here, we report the first case of unilateral facial nerve paralysis developed after 4 wks of intermittent cervical traction therapy. Nerve conduction velocity examination revealed a peripheral-type facial nerve paralysis. Symptoms of facial nerve paralysis subsided after prednisolone treatment and suspension of traction therapy. It is suspected that a misplaced or an overstrained harness may have been the cause of facial nerve paralysis in this patient. Possible causes were (1) direct compression by the harness on the right facial nerve near its exit through the stylomastoid foramen; (2) compression of the right external carotid artery by the harness, causing transient ischemic injury at the geniculate ganglion; or (3) coincidental herpes zoster virus infection or idiopathic Bell's palsy involving the facial nerve.

  11. 3 dimensional volume MR imaging of intratemporal facial nerve

    Seo, Jeong Jin; Kang, Heoung Keun; Kim, Hyun Ju; Kim, Jae Kyu; Jung, Hyun Ung; Moon, Woong Jae [Chonnam University Medical School, Kwangju (Korea, Republic of)


    To evaluate the usefulness of 3 dimensional volume MR imaging technique for demonstrating the facial nerves and to describe MR findings in facial palsy patients and evaluate the significance of facial nerve enhancement. We reviewed the MR images of facial nerves obtained with 3 dimensional volume imaging technique before and after intravenous administration of Gadopentetate dimeglumine in 13 cases who had facial paralysis and 33 cases who had no facial palsy. And we analyzed the detectability of ananatomical segments of intratemporal facial nerves and facial nerve enhancement. When the 3 dimensional volume MR images of 46 nerves were analyzed subjectively, the nerve courses of 43(93%) of 46 nerves were effectively demonstrated on 3 dimensional volume MR images. Internal acoustic canal portions and geniculate ganglion of facial nerve were well visualized on axial images and tympanic and mastoid segments were well depicted on oblique sagittal images. 10 of 13 patients(77%) were visibly enhanced along at least one segment of the facial nerve with swelling or thickening, and nerves of 8 of normal 33 cases(24%) were enhanced without thickening or swelling. MR findings of facial nerve parelysis is asymmetrical thickening of facial nerve with contrast enhancement. The 3 dimensional volume MR imaging technique should be a useful study for the evaluation of intratemporal facial nerve disease.

  12. Identifying traction-separation behavior of self-adhesive polymeric films from in situ digital images under T-peeling

    Nase, Michael; Rennert, Mirko; Naumenko, Konstantin; Eremeyev, Victor A.


    In this paper procedures are developed to identify traction-separation curves from digital images of the deformed flexible films during peeling. T-peel tests were performed for self-adhesive polymeric films. High quality photographs of the deformed shape within and outside the zone of adhesive interaction were made in situ by the digital light microscope. The deformed line is approximated by a power series with coefficients computed by minimizing a least squares functional. Two approaches to identify the traction-separation curve for the given deformation line are proposed. The first one is based on the energy integral of the non-linear theory of rods and allows the direct evaluation of the adhesion force potential. The second one utilizes the complementary energy type variational equation and the Ritz method to compute the adhesion force. The accuracy of both approaches is analyzed with respect to different approximations for the deformed line and the force of interaction. The obtained traction vs. axial coordinate and the traction-separation curves provide several properties of the adhesive system including the maximum adhesion force, the length of the adhesive zone and the equilibrium position, where the adhesive force is zero while the separation is positive.

  13. Digital Model of Railway Electric Traction Lines

    Garg, Rachana; Mahajan, Priya; Kumar, Parmod


    The characteristic impedance and propagation constant define the behavior of signal propagation over the transmission lines. The digital model for railway traction lines which includes railway tracks is developed, using curve fitting technique in MATLAB. The sensitivity of this model has been computed with respect to frequency. The digital sensitivity values are compared with the values of analog sensitivity. The developed model is useful for digital protection, integrated operation, control and planning of the system.

  14. Proximal sural traction neurectomy during transtibial amputations.

    Tintle, Scott M; Donohue, Michael A; Shawen, Scott; Forsberg, Jonathan A; Potter, Benjamin K


    Symptomatic neuroma formation after trauma-related transtibial amputations remains a clinical problem. The sural nerve is frequently overlooked in its vulnerable subcutaneous location in the posterior myofasciocutaneous flap and commonly leads to chronic pain and decreased prosthesis use. The standard sural traction neurectomy may actually predispose the sural neuroma to form in a region that becomes symptomatic with prosthesis wear. The proposed modified proximal sural traction neurectomy using a standard or extended posterior flap begins with identification of the sural nerve in the subcutaneous tissue of the distal flap in identical fashion to a standard sural neurectomy. In the proximal posterior flap, a limited anterior approach is then performed and gentle traction on the distal end of the sural nerve aids in the identification of the most proximally accessible portion of the medial sural cutaneous nerve. After locating the medial sural cutaneous nerve proximally, a neurectomy at this location is performed, allowing the retraction of the nerve into a healthy tissue bed substantially more proximal than with a standard sural neurectomy. This technique ensures that the resulting neuroma does not form directly at the distal end of the residual limb where it is, in our experience, more likely to become symptomatic.


    V. A. Zhirnov


    Full Text Available Based on the survey of 148 patients with an lumbar degenerative disease, there have been studied immediate and medium-term results of the comprehensive conservative treatment of the patients with and without application of traction exposure on the spine. It was found out that the traction of the spine leads to a quicker and more durable relief of symptoms in comparison with the control groups where traction therapy wasn't carried out. Application of the traction-extended therapy in three planes with a usage of robotized set for dry skeletal traction of a new generation KinetracKNX-7000 is proved to increase the effectiveness of treatment for the patients with stated pathology, fasten regress of the pain syndrome and clinical symptomatology, lead to more durable and lasting remission of the desease, in comparison with the patients that had traction of the spine in one plane only during the treatment.

  16. Interexaminer and intraexaminer reliabilities of 3-dimensional orthodontic digital setups

    Fabels, L.N.J.; Nijkamp, P.G.


    Introduction The use of digital orthodontic setups has grown quickly. The purpose of this study was to test the interexaminer and intraexaminer reliabilities of 3-dimensional orthodontic digital setups in OrthoCAD (Align Technology, San Jose, Calif). Methods Six clinicians made digital orthodontic s

  17. Differential Cross Section Kinematics for 3-dimensional Transport Codes

    Norbury, John W.; Dick, Frank


    In support of the development of 3-dimensional transport codes, this paper derives the relevant relativistic particle kinematic theory. Formulas are given for invariant, spectral and angular distributions in both the lab (spacecraft) and center of momentum frames, for collisions involving 2, 3 and n - body final states.

  18. [Potentialities of traction therapy for diskogenic compressive radicular syndromes].

    Ziniakov, N N; Ziniakov, N T


    This study included 78 patients with lumbar subligamentary herniation. Based on their clinical and functional examination, several variants of diskogenic radiculopathies were distinguished. Special emphasis was laid on the evaluation of efficiency of underwater vertical traction in these patients. The proposed method was shown to produce better effect than underwater horizontal traction when used for the treatment of both axonopathies and axonomyelinopathies. The efficiency of underwater vertical traction applied to the treatment of axonopathies appears to be higher than in patients with axonomyelinopathies.


    V. A. Zhirnov; D. P. Krest'yanov; A. K. Vasil'kin


    Based on the survey of 148 patients with an lumbar degenerative disease, there have been studied immediate and medium-term results of the comprehensive conservative treatment of the patients with and without application of traction exposure on the spine. It was found out that the traction of the spine leads to a quicker and more durable relief of symptoms in comparison with the control groups where traction therapy wasn't carried out. Application of the traction-extended therapy in three plan...


    V. A. Bratash


    Full Text Available In the article the calculation formulas for determination of unloadings (finish loadings of wheels and bendings of a spring suspension of eight-wheel electric locomotive DS3 with the traction transmission of the second kind at transmitting the traction forces from bogies to body by means of sloping rods are presented. The numeral calculations on the example of main line freight-and-passenger electric locomotive DS3 are performed.

  1. 3-Dimensional reconstruction of fluorescent structures in tardigrades

    Franz BRÜMMER


    Full Text Available Tardigrades are microscopic animals, thus brightfield microscopy is a well established method for tardigrade observation. Modern techniques in functional genetics like fluorescence in situ hybridisation or fluorescently labelled expression markers demand high resolution fluorescence microscopy. Nevertheless tardigrades are still considered to be difficult objects for fluorescence techniques as they are covered by an opaque and diffracting cuticle. We show a modern technique of structured light illumination that enables us to acquire thin optical sections and consequently to reconstruct 3-dimensional structures in tardigrades with a high spatial resolution in all 3 dimensions. This technique is evaluated on taxonomically valuable internal as well as external structures of eutardigrades: the bucco-pharyngeal apparatus and the claws. The 3-dimensional reconstructions allow the measurement of distances in all 3 dimensions.

  2. Wetting characteristics of 3-dimensional nanostructured fractal surfaces

    Davis, Ethan; Liu, Ying; Jiang, Lijia; Lu, Yongfeng; Ndao, Sidy


    This article reports the fabrication and wetting characteristics of 3-dimensional nanostructured fractal surfaces (3DNFS). Three distinct 3DNFS surfaces, namely cubic, Romanesco broccoli, and sphereflake were fabricated using two-photon direct laser writing. Contact angle measurements were performed on the multiscale fractal surfaces to characterize their wetting properties. Average contact angles ranged from 66.8° for the smooth control surface to 0° for one of the fractal surfaces. The change in wetting behavior was attributed to modification of the interfacial surface properties due to the inclusion of 3-dimensional hierarchical fractal nanostructures. However, this behavior does not exactly obey existing surface wetting models in the literature. Potential applications for these types of surfaces in physical and biological sciences are also discussed.

  3. Circuit-Switched Gossiping in the 3-Dimensional Torus Networks

    Delmas, Olivier; Pérennes, Stéphane


    In this paper we describe, in the case of short messages, an efficient gossiping algorithm for 3-dimensional torus networks (wrap-around or toroidal meshes) that uses synchronous circuit-switched routing. The algorithm is based on a recursive decomposition of a torus. The algorithm requires an optimal number of rounds and a quasi-optimal number of intermediate switch settings to gossip in an $7^i \\times 7^i \\times 7^i$ torus.

  4. Análisis de la fuerza isométrica en la propulsión y tracción en slalom en silla de ruedas y su relación con el rendimiento y la clasificación funcional. [Isometric force in wheelchair slalom during traction and propulsion and their relationship with performance and functional classification].

    Raúl Reina


    profiles of the Cerebral Palsy International Sports and Recreation Association, took part in the study (5 ♂ and 4 ♀. Participants performed two maximal isometric force tests (propulsion and traction with their competition wheelchairs in which maximum force (Fmax, average force (Fmed, execution time and time used to reach different Fmax percentages were recorded. In addition, participants carried out two specific performance tests: a 16 m linear sprint with an inversion door after 8 m; and two 4 m linear displacements with a zig-zag round trip. The measured variable was execution time using photocell gates. Significant differences were found between D3 and D4 in propulsion tests for Fmax (p = 0,007 and Fmean (p = 0,002, being this last one higher. Significant statistical differences were found between D2 and D3 in specific performance tests (inversion: p = 0,034 and zig-zag: p = 0,010, being D3 the quickest group. Results show a non-linear relationship between classification divisions and the performance.

  5. The Study of Several Variants of the Traction Drive with Middle-Frequency Transformer

    Martin Pittermann


    Full Text Available This paper presents research motivated by industrial demand for special traction drive topology devoted to minimization of traction transformer weight of traction vehicles. The main attention has been given to the special traction drive topology for AC power systems: input high voltage trolley converter (single phase – middle frequency transformer (single phase – output converter (single phase voltage-source active rectifier + three phase voltage-source inverter - traction motor. This configuration can minimize traction transformer weight against topology with classical 50Hz traction transformer. Several variants of innovative topologies of the traction vehicles fulfil the weight reduce requirements have beenpresented.

  6. Potential Development of Vehicle Traction Levitation Systems with Magnetic Suspension

    A.V. Kireev


    Full Text Available Below is given the brief analysis of development trend for vehicle traction levitation systems with magnetic suspension. It is presented the assessment of potential development of traction levitation systems in terms of their simplicity. The examples are considered of technical solutions focused on reducing the complexity of transport systems. It is proposed the forecast of their further development.

  7. Development of Traction Drive Motors for the Toyota Hybrid System

    Kamiya, Munehiro

    Toyota Motor Corporation developed in 2005 a new hybrid system for a large SUV. This system included the new development of a high-speed traction drive motor achieving a significant increase in power weight ratio. This paper provides an overview of the hybrid system, discusses the characteristics required of a traction drive motor, and presents the technologies employed in the developed motor.

  8. Computed tomographic evaluation of lumbar spinal structures during traction.

    Sari, Hidayet; Akarirmak, Ulkü; Karacan, Ilhan; Akman, Haluk


    In the previous studies, it is reported that traction diminishes the compressive load on intervertebral discs, reduces herniation, stretches lumbar spinal muscle and ligaments, decreases muscle spasm, and widens intervertebral foramina. The aim of this study was to evaluate the effects of horizontal motorized static traction on spinal anatomic structures (herniated area, spinal canal area, intervertebral disc heights, neural foraminal diameter, and m.psoas diameter) by quantitative measures in patients with lumbar disc herniation (LDH). At the same time the effect of traction in different localizations (median and posterolateral herniation) and at different levels (L4-L5 and L5-S1) was assessed. Thirty two patients with acute LDH participated in the study. A special traction system was used to apply horizontally-motorized static lumbar traction. Before and during traction a CT- scan was made to observe the changes in the area of spinal canal and herniated disc material, in the width of neural foramina, intervertebral disc heights, and in the thickness of psoas muscle. During traction, the area of protruded disc area, and the thickness of psoas muscle decreased 24.5% (p = 0.0001), and 5.7% (p = 0.0001), respectively. The area of the spinal canal and the width of the neural foramen increased 21.6% (p = 0.0001) and 26.7% (p = 0.0001), respectively. The anterior intervertebral disc height remained unchanged with traction however the posterior intervertebral disc height was significantly expanded. This study is the first to evaluated in detail and quantitatively the effect of motorized horizontal lumbar spinal traction on spinal structures and herniated area. According to detailed measures it was concluded that during traction of individuals with acute LDH there was a reduction of the size of the herniation, increased space within the spinal canal, widening of the neural foramina, and decreased thickness of the psoas muscle.

  9. Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness

    Marinković, Aleksandar; Mih, Justin D.; Park, Jin-Ah; Liu, Fei


    Lung fibroblast functions such as matrix remodeling and activation of latent transforming growth factor-β1 (TGF-β1) are associated with expression of the myofibroblast phenotype and are directly linked to fibroblast capacity to generate force and deform the extracellular matrix. However, the study of fibroblast force-generating capacities through methods such as traction force microscopy is hindered by low throughput and time-consuming procedures. In this study, we improved at the detail level methods for higher-throughput traction measurements on polyacrylamide hydrogels using gel-surface-bound fluorescent beads to permit autofocusing and automated displacement mapping, and transduction of fibroblasts with a fluorescent label to streamline cell boundary identification. Together these advances substantially improve the throughput of traction microscopy and allow us to efficiently compute the forces exerted by lung fibroblasts on substrates spanning the stiffness range present in normal and fibrotic lung tissue. Our results reveal that lung fibroblasts dramatically alter the forces they transmit to the extracellular matrix as its stiffness changes, with very low forces generated on matrices as compliant as normal lung tissue. Moreover, exogenous TGF-β1 selectively accentuates tractions on stiff matrices, mimicking fibrotic lung, but not on physiological stiffness matrices, despite equivalent changes in Smad2/3 activation. Taken together, these results demonstrate a pivotal role for matrix mechanical properties in regulating baseline and TGF-β1-stimulated contraction of lung fibroblasts and suggest that stiff fibrotic lung tissue may promote myofibroblast activation through contractility-driven events, whereas normal lung tissue compliance may protect against such feedback amplification of fibroblast activation. PMID:22659883

  10. The 3-dimensional architecture of the Upsilon Andromedae planetary system

    Deitrick, Russell; McArthur, Barbara; Quinn, Thomas R; Luger, Rodrigo; Antonsen, Adrienne; Benedict, G Fritz


    The Upsilon Andromedae system is the first exoplanetary system to have the relative inclination of two planets' orbital planes directly measured, and therefore offers our first window into the 3-dimensional configurations of planetary systems. We present, for the first time, full 3-dimensional, dynamically stable configurations for the 3 planets of the system consistent with all observational constraints. While the outer 2 planets, c and d, are inclined by about 30 degrees, the inner planet's orbital plane has not been detected. We use N-body simulations to search for stable 3-planet configurations that are consistent with the combined radial velocity and astrometric solution. We find that only 10 trials out of 1000 are robustly stable on 100 Myr timescales, or about 8 billion orbits of planet b. Planet b's orbit must lie near the invariable plane of planets c and d, but can be either prograde or retrograde. These solutions predict b's mass is in the range 2 - 9 $M_{Jup}$ and has an inclination angle from the...

  11. Automated feature extraction for 3-dimensional point clouds

    Magruder, Lori A.; Leigh, Holly W.; Soderlund, Alexander; Clymer, Bradley; Baer, Jessica; Neuenschwander, Amy L.


    Light detection and ranging (LIDAR) technology offers the capability to rapidly capture high-resolution, 3-dimensional surface data with centimeter-level accuracy for a large variety of applications. Due to the foliage-penetrating properties of LIDAR systems, these geospatial data sets can detect ground surfaces beneath trees, enabling the production of highfidelity bare earth elevation models. Precise characterization of the ground surface allows for identification of terrain and non-terrain points within the point cloud, and facilitates further discernment between natural and man-made objects based solely on structural aspects and relative neighboring parameterizations. A framework is presented here for automated extraction of natural and man-made features that does not rely on coincident ortho-imagery or point RGB attributes. The TEXAS (Terrain EXtraction And Segmentation) algorithm is used first to generate a bare earth surface from a lidar survey, which is then used to classify points as terrain or non-terrain. Further classifications are assigned at the point level by leveraging local spatial information. Similarly classed points are then clustered together into regions to identify individual features. Descriptions of the spatial attributes of each region are generated, resulting in the identification of individual tree locations, forest extents, building footprints, and 3-dimensional building shapes, among others. Results of the fully-automated feature extraction algorithm are then compared to ground truth to assess completeness and accuracy of the methodology.

  12. Materials applications of an advanced 3-dimensional atom probe

    Cerezo, A. [Oxford Univ. (United Kingdom). Dept. of Materials; Gibuoin, D. [Oxford Univ. (United Kingdom). Dept. of Materials; Kim, S. [Oxford Univ. (United Kingdom). Dept. of Materials; Sijbrandij, S.J. [Oxford Univ. (United Kingdom). Dept. of Materials; Venker, F.M. [Oxford Univ. (United Kingdom). Dept. of Materials]|[Rijksuniversiteit Groningen (Netherlands). Dept. of Applied Physics; Warren, P.J. [Oxford Univ. (United Kingdom). Dept. of Materials; Wilde, J. [Oxford Univ. (United Kingdom). Dept. of Materials; Smith, G.D.W. [Oxford Univ. (United Kingdom). Dept. of Materials


    An advanced 3-dimensional atom probe system has been constructed, based on an optical position-sensitive atom probe (OPoSAP) detector with energy compensation using a reflectron lens. The multi-hit detection capability of the OPoSAP leads to significant improvements in the efficiency of the instrument over the earlier serial position-sensing system. Further gains in efficiency are obtained by using a biassed grid in front of the detector to collect secondary electrons generated when ions strike the interchannel area. The improvement in detection efficiency gives enhanced performance in the studies of ordered materials and the determination of site occupation. Energy compensation leads to a much improved mass resolution (m/{Delta}m=500 full width at half maximum) making it possible to map out the 3-dimensional spatial distributions of all the elements in complex engineering alloys, even when elements lie close together in the mass spectrum. For example, in the analysis of a maraging steel, this allows separation between the {sup 61}Ni{sup 2+} and {sup 92}Mo{sup 3+} peaks, which are only 1/6 of a mass unit apart. (orig.).

  13. Cascade Control Solution for Traction Motor for Hybrid Electric Vehicles

    Zsuzsa Preitl


    Full Text Available In this paper a hybrid electric vehicle is considered, which contains both aninternal combustion engine and an electric motor (EM. Without focusing on the othercomponents of the vehicle, the EM is treated in detail, both regarding modelling aspectsand control solutions.After a brief modelling of the plant, two cascade speed control solutions are presented: firsta classical PI+PI cascade control solution is presented. The control systems related totraction electric motors (used in vehicle traction must be able to cope with differentrequests, such as variation of the reference signal, load disturbances which depend on thetransport conditions and parametric disturbances regarding changes in the total mass ofthe vehicle. For this purpose, in the design of the speed controller (external loop a specificmethodology based on extension of the symmetrical optimum method is presented. Thecontrollers are developed using the Modulus–Optimum method for the inner loop, and theExtended Symmetrical Optimum Method, corrected based on the 2p-SO-method, for theouter loop (for a more efficient disturbance rejection.In order to force the behaviour of the system regarding the reference input, a correctionterm is introduced as a non-homogenous structured PI controller solution.Simulations were performed using numerical values taken from a real applicationconsisting in a hybrid vehicle prototype, showing satisfactory behaviour.

  14. Resistência mecânica do solo e força de tração em hastes sulcadoras de semeadoras-adubadoras em sistema de integração lavoura-pecuária Mechanical resistance of soil and traction force by planter chisel type openers in crop-livestock system

    Osmar Conte


    Full Text Available A integração lavoura-pecuária, realizada mediante a implantação de pastagens no inverno e a semeadura de milho ou soja no verão, constitui-se numa alternativa para a diversificação de atividades e ampliação dos lucros. Animais em pastejo, principalmente em áreas agrícolas manejadas sob semeadura direta, podem resultar na compactação adicional do solo, diagnosticada geralmente pelo aumento de resistência do solo à penetração (RP. Com o objetivo de avaliar a correlação entre RP e força de tração (FT medida em hastes sulcadoras de semeadoras-adubadoras, nos anos de 2004 e 2005, foi conduzido um experimento em São Miguel das Missões - RS, em Latossolo Vermelho (0.540 kg kg-1 de argila. Os tratamentos consistiram em quatro intensidades de pastejo, que resultaram em alturas de pastagem de 10; 20; 30 e 40 cm, e de testemunha sem pastejo, organizados em DBC, com três repetições. Avaliou-se a RP, no final do período de pastejo, e na semeadura da soja, obteve-se a FT exigida nas hastes sulcadoras de semeadoras-adubadoras. A RP e a FT aumentaram com o incremento na intensidade de pastejo. A correlação entre essas variáveis foi significativa, comprovando que é possível avaliar o estado de compactação do solo por meio da medição da FT requerida pelas hastes sulcadoras de semeadoras-adubadoras.The use of crop-livestock integration systems, with forage implantation during winter and corn or soybean sown during summer, has become an alternative to activity diversification while magnifying profits. Cattle grazing, mainly in agricultural areas under no-tillage, can result in additional soil compaction, which can usually be diagnosed by increases in soil resistance to penetration (RP. Aiming to evaluate the correlation between RP and traction force (FT measured with cutting shafts, in the years of 2004 and 2005, an experiment was conducted in São Miguel das Missões - RS, Brazil, in an Oxisoil (0.540 kg kg-1 clay content


    G. K. Getman


    Full Text Available The method of determination of constituents of expense of electric power on traction of quarry trains is resulted in the article, and also the degree of their intercommunication with the mode of train motion is analysed.

  16. Mechanical Lumbar Traction: What Is Its Place in Clinical Practice?


    Summary evidence concludes that mechanical lumbar traction is not effective for treating acute or chronic nonspecific low back pain (LBP). However, many physical therapists continue to use it, primarily as an additional modality. Indeed, expert clinical opinion, theoretical models, and some research evidence suggest that certain patients with LBP respond positively to traction. A study published in the March 2016 issue of JOSPT investigates the effectiveness of traction in prone as an adjunct to an extension-oriented exercise program in patients with LBP and leg pain and explores whether a previously identified set of patient characteristics is associated with better outcomes from traction. In this Perspectives for Practice, the authors explain the impact of their findings for clinicians treating these patients.


    V. A. Bratash


    Full Text Available In the article the calculation formulas for determination of unloadings (finishings loadings of wheels and bendings of a spring suspension of 8-wheel electric locomotive DS 3 with the hauling transmission of the second kind at the transmission of tractive forces from the bogies to the body through sloping tractions are presented. Numerical calculations are executed on the example of mainline freight-and-passenger electric locomotive DS 3.

  18. Hamiltonian Formulation of Jackiw-Pi 3-Dimensional Gauge Theories

    Dayi, O F


    A 3-dimensional non-abelian gauge theory was proposed by Jackiw and Pi to create mass for the gauge fields. However, the set of gauge invariances of the quadratic action obtained by switching off the non-abelian interactions is larger than the original one. This inconsistency in the gauge invariances causes some problems in quantization. Jackiw and Pi proposed another action by enlarging the space of states whose gauge invariances are consistent with the quadratic part. It is shown that all of these theories yield the same number of physical degrees of freedom in the hamiltonian framework. Hence, as far as the physical states are considered there is no inconsistency. Nevertheless, perturbation expansion is still problamatic.

  19. α1 -AR agonist induced piloerection protects against the development of traction alopecia.

    Goren, Andy; Shapiro, Jerry; Sinclair, Rodney; Kovacevic, Maja; McCoy, John


    Traction alopecia is hair loss that occurs after persistent pulling (e.g., during cosmetic procedures) on the roots of hair over time. Unlike plucking, which is painful, persistent pulling may go unnoticed until a patient presents with either bald spots or diffuse telogen shedding. Each hair follicle in the scalp contains an arrector pili muscle that, when contracted, erects the hair. The smooth muscle in the arrector pili expresses α1 adrenergic receptors (α1 -AR). As such, we hypothesized that contraction of the arrector pili muscle via an α1 -AR agonist would increase the threshold of force required to pluck hair during cosmetic procedures. Female subjects, ages 18-40, were recruited to study the effect of topically applied phenylephrine, a selective α1 -AR agonist, on epilation force and hair shedding during cosmetic procedures. In our blinded study, 80% of subjects demonstrated reduced shedding on days using phenylephrine compared to days using a placebo solution. The average reduction in hair loss was approximately 42%. In addition, the force threshold required for epilation increased by approximately 172% following topical phenylephrine application. To our knowledge this is the first study demonstrating the utility of α1 -AR agonists in the treatment of traction alopecia and hair shedding during cosmetic procedures.

  20. Rare-Earth-Free Traction Motor: Rare Earth-Free Traction Motor for Electric Vehicle Applications



    REACT Project: Baldor will develop a new type of traction motor with the potential to efficiently power future generations of EVs. Unlike today’s large, bulky EV motors which use expensive, imported rare-earth-based magnets, Baldor’s motor could be light, compact, contain no rare earth materials, and have the potential to deliver more torque at a substantially lower cost. Key innovations in this project include the use of a unique motor design, incorporation of an improved cooling system, and the development of advanced materials manufacturing techniques. These innovations could significantly reduce the cost of an electric motor.

  1. Thermal crosstalk in 3-dimensional RRAM crossbar array.

    Sun, Pengxiao; Lu, Nianduan; Li, Ling; Li, Yingtao; Wang, Hong; Lv, Hangbing; Liu, Qi; Long, Shibing; Liu, Su; Liu, Ming


    High density 3-dimensional (3D) crossbar resistive random access memory (RRAM) is one of the major focus of the new age technologies. To compete with the ultra-high density NAND and NOR memories, understanding of reliability mechanisms and scaling potential of 3D RRAM crossbar array is needed. Thermal crosstalk is one of the most critical effects that should be considered in 3D crossbar array application. The Joule heat generated inside the RRAM device will determine the switching behavior itself, and for dense memory arrays, the temperature surrounding may lead to a consequent resistance degradation of neighboring devices. In this work, thermal crosstalk effect and scaling potential under thermal effect in 3D RRAM crossbar array are systematically investigated. It is revealed that the reset process is dominated by transient thermal effect in 3D RRAM array. More importantly, thermal crosstalk phenomena could deteriorate device retention performance and even lead to data storage state failure from LRS (low resistance state) to HRS (high resistance state) of the disturbed RRAM cell. In addition, the resistance state degradation will be more serious with continuously scaling down the feature size. Possible methods for alleviating thermal crosstalk effect while further advancing the scaling potential are also provided and verified by numerical simulation.

  2. Mandibular reconstruction using stereolithographic 3-dimensional printing modeling technology.

    Cohen, Adir; Laviv, Amir; Berman, Phillip; Nashef, Rizan; Abu-Tair, Jawad


    Mandibular reconstruction can be challenging for the surgeon wishing to restore its unique geometry. Reconstruction can be achieved with titanium bone plates followed by autogenous bone grafting. Incorporation of the bone graft into the mandible provides continuity and strength required for proper esthetics and function and permitting dental implant rehabilitation at a later stage. Precious time in the operating room is invested in plate contouring to reconstruct the mandible. Rapid prototyping technologies can construct physical models from computer-aided design via 3-dimensional (3D) printers. A prefabricated 3D model is achieved, which assists in accurate contouring of plates and/or planning of bone graft harvest geometry before surgery. The 2 most commonly used rapid prototyping technologies are stereolithography and 3D printing (3DP). Three-dimensional printing is advantageous to stereolithography for better accuracy, quicker printing time, and lower cost. We present 3 clinical cases based on 3DP modeling technology. Models were fabricated before the resection of mandibular ameloblastoma and were used to prepare bridging plates before the first stage of reconstruction. In 1 case, another model was fabricated and used as a template for iliac crest bone graft in the second stage of reconstruction. The 3DP technology provided a precise, fast, and cheap mandibular reconstruction, which aids in shortened operation time (and therefore decreased exposure time to general anesthesia, decreased blood loss, and shorter wound exposure time) and easier surgical procedure.

  3. Pneumatic release of focal vitreomacular traction.

    Claus, M G; Feron, E; Veckeneer, M


    PurposeTo study the efficacy of a single intravitreal injection of expansile gas as a valuable alternative to current treatment options (conservative, pharmacological, and surgical) in patients with symptomatic, focal vitreomacular traction (VMT).Patients and methodsThis study comprises a retrospective, interventional case series of patients. Twenty eyes in seventeen patients with symptomatic and persisting focal VMT were treated in an outpatient setting with an intravitreal gas injection of 0.2 ml. In 19 eyes, 100% hexafluoroethane (C2F6) was used. One eye received sulfur hexafluoride (SF6). To all but three patients posturing advice was given. Patients were reviewed with a full-eye examination and ocular coherence tomography (OCT) after 14 days and later. The primary outcome measure was the release of VMT on OCT.ResultsIn 17 of the 20 (85.0%) treated eyes, a release of VMT was achieved as documented on OCT. The release of VMT was diagnosed during the first month after injection in 11 eyes of 11 patients and within 3 months in 16 eyes of 15 patients. In all but five of our patients, best corrected visual acuity (BCVA) remained stable or improved. In four patients, the progression or development of cataract was the probable cause of the decrease in BCVA. One patient developed a stage II macular hole after injection and needed vitrectomy. None of the treated patients developed retinal breaks.ConclusionIntravitreal expansile gas injection could offer a minimally invasive, low-cost alternative treatment in patients with symptomatic, persisting VMT. Additional studies on a larger number of patients are required.

  4. Advantages of diabetic tractional retinal detachment repair

    Sternfeld, Amir; Axer-Siegel, Ruth; Stiebel-Kalish, Hadas; Weinberger, Dov; Ehrlich, Rita


    Purpose To evaluate the outcomes and complications of patients with diabetic tractional retinal detachment (TRD) treated with pars plana vitrectomy (PPV). Patients and methods We retrospectively studied a case series of 24 eyes of 21 patients at a single tertiary, university-affiliated medical center. A review was carried out on patients who underwent PPV for the management of TRD due to proliferative diabetic retinopathy from October 2011 to November 2013. Preoperative and final visual outcomes, intraoperative and postoperative complications, and medical background were evaluated. Results A 23 G instrumentation was used in 23 eyes (95.8%), and a 25 G instrumentation in one (4.2%). Mean postoperative follow-up time was 13.3 months (4–30 months). Visual acuity significantly improved from logarithm of the minimum angle of resolution (LogMAR) 1.48 to LogMAR 1.05 (P<0.05). Visual acuity improved by ≥3 lines in 75% of patients. Intraoperative complications included iatrogenic retinal breaks in seven eyes (22.9%) and vitreal hemorrhage in nine eyes (37.5%). In two eyes, one sclerotomy was enlarged to 20 G (8.3%). Postoperative complications included reoperation in five eyes (20.8%) due to persistent subretinal fluid (n=3), vitreous hemorrhage (n=1), and dislocated intraocular lens (n=1). Thirteen patients (54.2%) had postoperative vitreous hemorrhage that cleared spontaneously, five patients (20.8%) required antiglaucoma medications for increased intraocular pressure, seven patients (29.2%) developed an epiretinal membrane, and two patients (8.3%) developed a macular hole. Conclusion Patients with diabetic TRD can benefit from PPV surgery. Intraoperative and postoperative complications can be attributed to the complexity of this disease. PMID:26604667

  5. [Neurogenic bladder caused by spinal cord traction].

    Garat, J M; Aragona, F; Martinez, E


    A neurogenic bladder was the presenting syndrome in three cases of spinal cord traction. Of the typical symptomatic triad: neuro-orthopedic, cutaneous and urologic, the latter was of primary importance. Symptoms in the first case were incomplete bladder retention with distention of upper urinary tract, right-sided vesicorenal reflux and renal insufficiency. Six months after excision of a sacral lipoma and freeing of the filum terminale, micturition had become normal without residue, and renal function normalized. Right-sided reflux was corrected by submucosal advancement surgery with good results. The clinical history was more suggestive in the second case. Although inaugural symptoms were mictional, there was foot paralysis and a retrosacral lipoma above an abnormal hairy tuft in the upper part of the gluteal cleft. Operation revealed the presence of a dermoid cyst and a lipoma. Their excision combined with section of the filum terminale allowing ascension of the medullary cone. Marked clinical and urodynamic improvement was obtained with normal micturition and disappearance of incontinence. An anti-reflux operation suppressed residual reflux with good urographic results. Marked improvement in mictional disorders was obtained also in the 3rd case after excision of a sacral extradural lipoma and section of the filum terminale, allowing objective ascension of the medullary cone by 4 cm. A very detailed analysis was conducted of similar cases reported in the literature, about 2% of neurogenic bladders in children being affected. The importance of early diagnosis is emphasized as well as the essential need to establish a precise diagnosis of the lipoma of cauda equina and of medullary fixation. Early neurosurgery is justified by the high frequency of improvement in cases treated in this way.

  6. Effect of Traffic and Tillage on Agriculture Machine Traction and Fuel Consumption in Northern China Plain

    Hao Chen


    Full Text Available Controlled traffic with conservation tillage can reduce soil compaction, thus to improve operation performance and fuel consumption of agricultural machine. Northern Chinese Plain is one of the main agricultural production bases with high level of agricultural mechanization. To explore the effect of wheel traffic on machine traction force and fuel consumption, three treatments were conducted: zero tillage with Controlled Traffic (NTCN, Compacted Treatment (CT and traditional tillage system with random traffic (CK. Results showed that wheel traffic increased soil bulk density in the top soil layer in both fully compacted and random compacted plots. Controlled traffic system should certain potential on soil compaction amelioration. Controlled traffic system reduced traction force on winter wheat planting by 9.5 and 6.3%, compared with fully compacted treatment and random compacted treatment. Controlled traffic system reduced fuel consumption in both winter wheat planting and sub soiling (significantly, compared with fully compacted treatment and random compacted treatment. Results indicated that controlled traffic system had certain advantages in soil compaction and fuel consumption in this region and with high application potential.

  7. The Simulation of the Traction Drive with Middle-Frequency Transformer

    Miroslav Los


    Full Text Available This paper presents research motivated by industrial demand for special traction drive topology devoted to minimization of traction transformer weight against topology with classical 50Hz traction transformer. The special traction drive topology for AC power systems consists of input high voltage trolley converter (single phase matrix converter –middle frequency transformer - output converter - traction motor has been described. The main attention has been given tothe control algorithm of the traction topology (inserting of NULL vector of matrix converter and Two-value control ofsecondary active rectifier.

  8. Maximum Safety Regenerative Power Tracking for DC Traction Power Systems

    Guifu Du


    Full Text Available Direct current (DC traction power systems are widely used in metro transport systems, with running rails usually being used as return conductors. When traction current flows through the running rails, a potential voltage known as “rail potential” is generated between the rails and ground. Currently, abnormal rises of rail potential exist in many railway lines during the operation of railway systems. Excessively high rail potentials pose a threat to human life and to devices connected to the rails. In this paper, the effect of regenerative power distribution on rail potential is analyzed. Maximum safety regenerative power tracking is proposed for the control of maximum absolute rail potential and energy consumption during the operation of DC traction power systems. The dwell time of multiple trains at each station and the trigger voltage of the regenerative energy absorbing device (READ are optimized based on an improved particle swarm optimization (PSO algorithm to manage the distribution of regenerative power. In this way, the maximum absolute rail potential and energy consumption of DC traction power systems can be reduced. The operation data of Guangzhou Metro Line 2 are used in the simulations, and the results show that the scheme can reduce the maximum absolute rail potential and energy consumption effectively and guarantee the safety in energy saving of DC traction power systems.

  9. Development of Multi-function Cervical Vertebra and Lumbar Vertebra Traction Treatment Apparatus%多功能颈腰椎牵引治疗仪的研制

    赵东亮; 郭艳幸; 冯坤


    Objective To develop a kind of multi-function cervical vertebra and lumbar vertebra treatment apparatus which can realize constant traction in lumbar and cervical spine. Methods The traction force and treatment time got automatic control by using single chip microcomputer technology, through which, continuous traction, intermittent traction and other models can be realized. Results The developed prototype has the advantages of convenient use and small volume. Traction control precision can reach ± 1N. The treatment time can accurate to one second. Conclusion The traction force and the treatment time can be controlled accurately according to the treatment needs, which could make the treatment more effective.%目的:研制一种可以对颈椎和腰椎实现多种模式牵引的多功能治疗仪。方法采用单片机技术对牵引力和治疗时间进行自动控制,实现连续牵引、间歇牵引等多种模式。结果研制出的样机体积小巧、使用方便,牵引力控制精度和间歇治疗时间精确度均达到了设计要求。结论牵引力和治疗时间可根据治疗需求任意精确控制,使得治疗效果更显著。

  10. A new preclinical 3-dimensional agarose colony formation assay.

    Kajiwara, Yoshinori; Panchabhai, Sonali; Levin, Victor A


    The evaluation of new drug treatments and combination treatments for gliomas and other cancers requires a robust means to interrogate wide dose ranges and varying times of drug exposure without stain-inactivation of the cells (colonies). To this end, we developed a 3-dimensional (3D) colony formation assay that makes use of GelCount technology, a new cell colony counter for gels and soft agars. We used U251MG, SNB19, and LNZ308 glioma cell lines and MiaPaCa pancreas adenocarcinoma and SW480 colon adenocarcinoma cell lines. Colonies were grown in a two-tiered agarose that had 0.7% agarose on the bottom and 0.3% agarose on top. We then studied the effects of DFMO, carboplatin, and SAHA over a 3-log dose range and over multiple days of drug exposure. Using GelCount we approximated the area under the curve (AUC) of colony volumes as the sum of colony volumes (microm2xOD) in each plate to calculate IC50 values. Adenocarcinoma colonies were recognized by GelCount scanning at 3-4 days, while it took 6-7 days to detect glioma colonies. The growth rate of MiaPaCa and SW480 cells was rapid, with 100 colonies counted in 5-6 days; glioma cells grew more slowly, with 100 colonies counted in 9-10 days. Reliable log dose versus AUC curves were observed for all drugs studied. In conclusion, the GelCount method that we describe is more quantitative than traditional colony assays and allows precise study of drug effects with respect to both dose and time of exposure using fewer culture plates.

  11. Traction sheave elevator, hoisting unit and machine space

    Hakala, Harri; Mustalahti, Jorma; Aulanko, Esko


    Traction sheave elevator consisting of an elevator car moving along elevator guide rails, a counterweight moving along counterweight guide rails, a set of hoisting ropes (3) on which the elevator car and counterweight are suspended, and a drive machine unit (6) driving a traction sheave (7) acting on the hoisting ropes (3) and placed in the elevator shaft. The drive machine unit (6) is of a flat construction. A wall of the elevator shaft is provided with a machine space with its open side facing towards the shaft, the essential parts of the drive machine unit (6) being placed in the space. The hoisting unit (9) of the traction sheave elevator consists of a substantially discoidal drive machine unit (6) and an instrument panel (8) mounted on the frame (20) of the hoisting unit.

  12. [The effect of indomethacin suppository in preventing mesenteric traction syndrome].

    Koyama, K; Kaneko, I; Mori, K


    Mesenteric traction syndrome consists of cutaneous hyperemia with hypotension and tachycardia. NSAIDs could inhibit the phenomenon, but there are few reports about when to administer these drugs. In this study, we evaluated the effect of indomethacin on preventing mesenteric traction syndrome when administered preoperatively and just after induction of anesthesia. Thirty-six patients scheduled for abdominal hysterectomy were studied. Patients were randomized into three groups. Group C (n = 12); control, group T (n = 12); indomethacin 50 mg suppository just after induction of anesthesia, group P (n = 12); indomethacin 50 mg suppository about 90 min before incision. The effect of indomethacin was evaluated from the extent of cutaneous hyperemia. MTS was suppressed in group P, but not in group T (P traction syndrome.

  13. Advantages of diabetic tractional retinal detachment repair

    Sternfeld A


    Full Text Available Amir Sternfeld, Ruth Axer-Siegel, Hadas Stiebel-Kalish, Dov Weinberger, Rita Ehrlich Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petach Tikva, Israel Purpose: To evaluate the outcomes and complications of patients with diabetic tractional retinal detachment (TRD treated with pars plana vitrectomy (PPV.Patients and methods: We retrospectively studied a case series of 24 eyes of 21 patients at a single tertiary, university-affiliated medical center. A review was carried out on patients who underwent PPV for the management of TRD due to proliferative diabetic retinopathy from October 2011 to November 2013. Preoperative and final visual outcomes, intraoperative and postoperative complications, and medical background were evaluated.Results: A 23 G instrumentation was used in 23 eyes (95.8%, and a 25 G instrumentation in one (4.2%. Mean postoperative follow-up time was 13.3 months (4–30 months. Visual acuity significantly improved from logarithm of the minimum angle of resolution (LogMAR 1.48 to LogMAR 1.05 (P<0.05. Visual acuity improved by ≥3 lines in 75% of patients. Intraoperative complications included iatrogenic retinal breaks in seven eyes (22.9% and vitreal hemorrhage in nine eyes (37.5%. In two eyes, one sclerotomy was enlarged to 20 G (8.3%. Postoperative complications included reoperation in five eyes (20.8% due to persistent subretinal fluid (n=3, vitreous hemorrhage (n=1, and dislocated intraocular lens (n=1. Thirteen patients (54.2% had postoperative vitreous hemorrhage that cleared spontaneously, five patients (20.8% required antiglaucoma medications for increased intraocular pressure, seven patients (29.2% developed an epiretinal membrane, and two patients (8.3% developed a macular hole.Conclusion: Patients with diabetic TRD can benefit from PPV surgery. Intraoperative and postoperative complications can be attributed to the complexity of this disease. Keywords: diabetic retinopathy, proliferative

  14. 3-dimensional lattice studies of the electroweak phase transition at M$_{Higgs}$ $\\appprox$ 70 GeV

    Gürtler, M; Kripfganz, J; Perlt, H; Schiller, A


    We study the electroweak phase transition by lattice simulations of an effective 3--dimensional theory, for a Higgs mass of about 70 GeV. Exploiting, among others, a variant of the equal weight criterion of phase equilibrium, we obtain transition temperature, latent heat and surface tension, and compare with M_H approx 35 GeV. In the broken phase masses and Higgs condensates are compared to perturbation theory. For the symmetric phase, bound state masses and the static force are determined.


    T. M. Serdiuk


    Full Text Available The original automated method of measurement of electrical noise in the return electric-traction network is proposed. It is realized on the base of car-laboratory “Automatics, telemechanics and communication”. The mathematic model of return electric-traction network is developed to scientific bases of automated measurement. It allows us obtaining the mathematic expressions for change of voltage and current harmonics in the rail net and taking into account the inhomogeneity of lines for the following analytic determination of a source of electric noise.

  16. Fault Location in Power Electrical Traction Line System

    Yimin Zhou


    Full Text Available In this paper, methods of fault location are discussed in electrical traction single-end direct power supply network systems. Based on the distributed parameter model of the system, the position of the short-circuit fault can be located with the aid of the current and voltage value at the measurement end of the electrical traction line. Furthermore, the influence of the transient resistance, the position of the locomotive, locomotive load for fault location are also discussed. MATLAB simulation tool is used for the simulation experiments. Simulation results are proved the effectiveness of the proposed algorithms.

  17. Adhesion energy, surface traction and surface tension in liquid xenon

    B Mathew; G A Adebayo


    We calculated the adhesion energy, the surface traction and the surface energy of liquid xenon using molecular dynamics (MD) simulation. The value of the adhesion energy for liquid xenon at a reduced density of 0.630 was found to be 0.591 J/m2 and the surface traction has a peak at = 3.32 Å. It was observed that the attraction of the molecules in the liquid surface which produces a resistance to penetration decreases with temperature. This may be attributed to the greater average separation of molecules at higher temperature.


    Ling Weiqing; Liu Gang; Xie Youbai


    Based on improved test rig with cooling system,the traction experiments for 4109 Chinese aviation lubricant are tested under various simulated working conditions.Both the experimental data thanks to their accuracy and stability and the better cooling effect of the electric shafts has given the rationality of the experimental rig a strong support.An empirical equation for calculating the traction coefficient of 4109 lubricant,which may be conveniently used for engineering application,is obtained.Furthermore,the rheological properties of the lubricant are investigated.

  19. Analysis of 3-dimensional finite element after reconstruction of impaired ankle deltoid ligament.

    Ji, Yunhan; Tang, Xianzhong; Li, Yifan; Xu, Wei; Qiu, Wenjun


    We compared four repair techniques for impaired ankle ligament deltoideum, namely Wiltberger, Deland, Kitaoka and Hintermann using a 3-dimensional finite element. We built an ankle ligament deltoideum model, including six pieces of bone structures, gristles and main ligaments around the ankle. After testing the model, we built an impaired ligament deltoideum model plus four reconstruction models. Subsequently, different levels of force on ankles with different flexion were imposed and ankle biomechanics were compared. In the course of bending, from plantar flexion 20° to back flexion 20°, the extortion of talus decreased while the eversion increased. Four reconstruction models failed to bring back the impaired ankle to normal, with an obvious increase of extortion and eversion. The Kitaoka technique was useful to reduce the extortion angle in a consequential manner. Compared with the other three techniques, the Kitaoka technique produced better results for extortion angle and the difference was statistically significant. However, in case of eversion, there was no significant difference among the four techniques (P>0.05). Lateral ligament's stress in all the four models was different from the normal one. When the ankle was imposed with extortion moment of force, stress of anterior talofibular ligament with the Kitaoka reconstruction method was close to that of the complete deltoid ligament. When ankle was imposed with eversion moment of force, stress of anterior talofibular ligament with Kitaoka and Deland reconstruction methods were close to that of the complete deltoid ligament. We concluded that Kitaoka and Deland tendon reconstruction technique could recover impaired ankle deltoid ligament and re-established its normal biomechanics characteristics.


    A. V. Petrov


    Full Text Available The research results showing an opportunity to use a power quality rating in a system of direct current electric traction on a traction substation input and output are stated. It is demonstrated that these ratings essentially simplify the quality analysis of power coming into traction circuits.

  1. 21 CFR 888.5850 - Nonpowered orthopedic traction apparatus and accessories.


    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nonpowered orthopedic traction apparatus and... HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES Surgical Devices § 888.5850 Nonpowered orthopedic traction apparatus and accessories. (a) Identification. A nonpowered orthopedic traction...

  2. Design of Spiral Wheel Horizontal Well Traction Robot%螺旋轮式水平井牵引机器人设计与分析∗

    吴超群; 刘晨阳; 刘明尧; 张凤辉; 张玺亮


    In order to efficiently transport horizontal well operation tools, a spiral drive⁃based traction robot is designed. A support bar mechanism in parallelogram is proposed, and the screw nut adjusting mechanism and flexi⁃ble spring support are adopted to meet pipe diameter changes. The positive pressure of centralized wheel and pipe wall is analyzed and a traction model for robot is established. A virtual prototype of traction robot is built by using Pro/E and ADAMS software, simulation analysis is conducted for positive pressure and traction force of the drive wheel, and pipeline test conditions are set up to conduct the robot traction force test. Test results indicate that the robot can steadily move in the pipeline with the inner diameter of 125 mm and its traction force is up to 5. 4 kN. The results have important engineering significance on design of horizontal well propeller with large traction force.%针对水平井作业工具输送困难的问题,设计了基于螺旋驱动原理的牵引机器人。提出了一种平行四边形支撑杆机构,采用丝杠螺母调节机构和弹簧柔性支撑来适应管径变化。对扶正机构轮与管壁的正压力进行分析,并建立了机器人的牵引力模型。应用P ro/E和ADAMS软件建立牵引机器人的虚拟样机,对驱动轮的正压力和牵引力进行仿真分析,搭建了管道试验环境进行机器人牵引力试验。试验结果表明:该机器人能够在内径125 mm的管道中平稳行进,最大牵引力能达到5400 N。研究结果对于设计较大牵引力的水平井推进器具有重要的工程意义。

  3. Mesenchymal Stem Cells Ability to Generate Traction Stress in Response to Substrate Stiffness is Modulated by the Changing Extracellular Matrix Composition of the Heart During Development

    Gershlak, Joshua R.; Resnikoff, Joshua IN; Sullivan, Kelly E; Williams, Corin; Wang, Raymond M.; Black, Lauren D.


    In this study we present a novel method for studying cellular traction force generation and mechanotransduction in the context of cardiac development. Rat hearts from three distinct stage of development (fetal, neonatal and adult) were isolated, decellularized and characterized via mechanical testing and protein compositional analysis. Stiffness increased ~2 fold between fetal and neonatal time points but not between neonatal and adult. Composition of structural extracellular matrix (ECM) proteins was significantly different between all three developmental ages. ECM that was solubilized via pepsin digestion was cross-linked into polyacrylamide gels of varying stiffness and traction force microscopy was used to assess the ability of mesenchymal stem cells (MSCs) to generate traction stress against the substrates. The response to increasing stiffness was significantly different depending on the developmental age of the ECM. An investigation into early cardiac differentiation of MSCs demonstrated a dependence of the level of expression of early cardiac transcription factors on the composition of the complex ECM. In summary, this study found that complex ECM composition plays an important role in modulating a cell’s ability to generate traction stress against a substrate, which is a significant component of mechanotransductive signaling. PMID:23994333


    S. V. Pylypenko


    Full Text Available In the article the results of dynamic running and traction-energy tests of the electric locomotive VL40U are presented. In accordance with the test results a conclusion about the suitability of electric locomotive of such a type for operation with trains containing up to 15 passenger coaches inclusive is made.


    A. I. Safonov


    Full Text Available The paper analyzes factors that determine dynamic loads of mechanical transmission of trolleybus traction driving gear. The paper proposes a methodology for determination of calculative moments of loading transmission elements. Results of the research are analyzed and recommendations on  dynamic reduction of trolleybus transmission are given in the paper. 

  6. Apicotomy as Treatment for Failure of Orthodontic Traction

    Leandro Berni Osório


    Full Text Available Objective. The purpose of this study was to present a case report that demonstrated primary failure in a tooth traction that was subsequently treated with apicotomy technique. Case Report. A 10-year-old girl had an impacted upper right canine with increased pericoronal space, which was apparent on a radiographic image. The right maxillary sinus showed an opacity suggesting sinusitis. The presumptive diagnosis was dentigerous cyst associated with maxillary sinus infection. The plan for treatment included treatment of the sinus infection and cystic lesion and orthodontic traction of the canine after surgical exposure and bonding of an orthodontic appliance. The surgical procedure, canine position, root dilaceration, and probably apical ankylosis acted in the primary failure of the orthodontic traction. Surgical apical cut of the displaced teeth was performed, and tooth position in the dental arch was possible, with a positive response to the pulp vitality test. Conclusion. Apicotomy is an effective technique to treat severe canine displacement and primary orthodontic traction failure of palatally displaced canines.

  7. Structural strength analysis and fatigue life prediction of traction converter box in high-speed EMU

    Tan, Qin; Li, Qiang


    The method of building the FEA model of traction converter box in high-speed EMU and analyzing the static strength and fatigue strength of traction converter box based on IEC 61373-2010 and EN 12663 standards is presented in this paper. The load-stress correlation coefficients of weak points is obtained by FEA model, applied to transfer the load history of traction converter box to stress history of each point. The fatigue damage is calculated based on Miner's rule and the fatigue life of traction converter box is predicted. According to study, the structural strength of traction converter box meets design requirements.

  8. Research on a New Bilateral Self-locking Mechanism for an Inchworm Micro In-pipe Robot with Large Traction

    Junhong Yang


    Full Text Available In this paper, we present an innovative bilaterally-controllable self-locking mechanism that can be applied to the micro in-pipe robot. The background and state of the art of the inchworm micro in-pipe robot is briefly described in the very beginning of the paper, where the main factors that influence the traction ability are also discussed. Afterwards, the micro in-pipe robots’ propulsion principle based on a unidirectional self- locking mechanism is discussed. Then, several kinds of self-locking mechanisms are compared, and a new bilaterally-controllable self-locking mechanism is proposed. By implementing the self-locking mechanism, the robot’s tractive force is no longer restricted by the friction force, and both two-way motion and position locking for the robot can be achieved. Finally, the traction experiment is conducted using a prototype robot with the new bilaterally-controllable self-locking mechanism. Test results show that this new self-locking mechanism can adapt itself to a diameter of Φ17~Φ20 mm and has a blocking force up to 25N, and the maximum tractive force of the in-pipe robot based on such a locking mechanism is 12N under the maximum velocity of 10mm/s.

  9. Retinal Changes Induced by Epiretinal Tangential Forces

    Mario R. Romano


    Full Text Available Two kinds of forces are active in vitreoretinal traction diseases: tangential and anterior-posterior forces. However, tangential forces are less characterized and classified in literature compared to the anterior-posterior ones. Tangential epiretinal forces are mainly due to anomalous posterior vitreous detachment (PVD, vitreoschisis, vitreopapillary adhesion (VPA, and epiretinal membranes (ERMs. Anomalous PVD plays a key role in the formation of the tangential vectorial forces on the retinal surface as consequence of gel liquefaction (synchysis without sufficient and fast vitreous dehiscence at the vitreoretinal interface. The anomalous and persistent adherence of the posterior hyaloid to the retina can lead to vitreomacular/vitreopapillary adhesion or to a formation of avascular fibrocellular tissue (ERM resulting from the proliferation and transdifferentiation of hyalocytes resident in the cortical vitreous remnants after vitreoschisis. The right interpretation of the forces involved in the epiretinal tangential tractions helps in a better definition of diagnosis, progression, prognosis, and surgical outcomes of vitreomacular interfaces.

  10. Research of the multipolar induction traction frequency regulated motor

    V. Ia. Bespalov


    Full Text Available The paper considers the application features of traction induction electric motors in transmissions of vehicles. It shows that one of important stages in their designing is to choose the number of poles. In traction electric drives engines with the raised number of poles without comprehensive assessment of such solution are often applied. The paper investigates dynamic and power characteristics of the multi-polar traction asynchronous engine (TAE designed and made for using in the individual electric drive of heavy-load wheeled cars. The basic functional elements of the model to simulate the electric drive in Matlab environment with the Simulink and SimPower Systems applications in the structure with vector control are described, and the simulation modeling results of its dynamic mechanical characteristics are provided. It is established that because of increased alternating frequency of currents of the multi-polar engine in the range of high speeds there is an excessive decrease in the torque and the requirement for constancy of the target capacity, corresponding to the specified traction characteristic is not fulfilled. It is a consequence of the waveform distortion of engine phase current in the range of high speeds because of incapability of the power source to compensate an increasing EMF of movement as the speed continues to grow.The paper studies the influence of increased current frequencies on the additional losses in the engine. The analysis of electromagnetic field penetration depth in the copper conductor of stator winding at high frequency allowed us to establish a significant skin – effect. The quantitative assessment is given to this phenomenon by results of numerical calculation of electromagnetic field distribution in a stator groove. Significant increase in additional losses in the engine is established, and estimates of flow loss extent because of damping actions of eddy currents in the laminated steel of stator at

  11. Experimental evaluation of 3-dimensional kinematic behavior of the cruciate ligaments Avaliação experimental do comportamento cinemático tridimensional dos ligamentos cruzados

    Silvio Antonio Garbelotti Júnior; Osvaldo Pelozo Júnior; Rogério Pedreschi Caldana; Amâncio Ramalho Jr; Ricardo Luiz Smith


    PURPOSE: The purpose of this study was to evaluate a low-cost and easily reproducible technique for biomechanical studies in cadavers. In this kind of study, the natural effect of loading of the joint and shear forces are not taken into account. The objective is to describe the plastic deformation of the ligaments into 3-dimensional space. METHOD: For 18 intact human cadaver knees, the cruciate ligaments were divided into 3 fiber bundles, the tibial or femoral fixation points were marked, and...


    LI Yong-chi; YAO Lei; HU Xiu-zhang; CAO Jie-dong; DONG Jie


    Based on the general conservation laws in continuum mechanics, the Eulerian and Lagrangian descriptions of the jump conditions of shock waves in 3-dimensional solids were presented respectively. The implication of the jump conditions and their relations between each other, particularly the relation between the mass conservation and the displacement continuity, were discussed. Meanwhile the shock wave response curves in 3-dimensional solids, i.e. the Hugoniot curves were analysed, which provide the foundation for studying the coupling effects of shock waves in 3-dimensional solids.

  13. Topological Entropy and Renormalization group flow in 3-dimensional spherical spaces

    Asorey, M; Cavero-Peláez, I; D'Ascanio, D; Santangelo, E M


    We analyze the renormalization group flow of the temperature independent term of the entropy in the high temperature limit \\beta/a S^IR_top between the topological entropies of the conformal field theories connected by such flow. From a 3-dimensional viewpoint the same term arises in the 3-dimensional Euclidean effective action and has the same monotone behavior under the RG group flow. We conjecture that such monotonic behavior is generic, which would give rise to a 3-dimensional generalization of the c-theorem, along the lines of the 2-dimensional c-theorem and the 4-dimensional a-theorem.


    Zhang Xianjie; William E.Tobler; Zhang Yi; Zou Zhanjiang


    A computer model for the performance simulation of vehicles equipped with traction drive continuously variable transmission (CVT) is presented. The model integrates the traction drive CVT subsystem into an existing overall vehicle system. The characteristics of engine output torque are formulated using neural networks, and torque converter is modeled using lookup tables. Component inputs and outputs are coupled in the dynamic equations and interfaces in the powertrain system. The model simulation can provide evaluation of vehicle performance in drivability, fuel economy and emission levels for various drive ranges prior to the prototyping of the vehicle. As a design tool, the model assists engineers in understanding the effect of powertrain components on vehicle performance and making decisions in the selection of key design parameters. The model is implemented in the MATLAB/Simulink environment. The performance simulation of a test vehicle is included as a numerical example to illustrate the effectiveness of the model.

  15. Systematic traction techniques in minimal-access pediatric cardiac surgery.

    Oiwa, Hiroshi; Ishida, Ryoichi; Sudo, Kenichi


    Minimal-access pediatric cardiac surgery is now common in the treatment of simple congenital heart defects. However, methods of securing a good, unobstructed view for surgery and the difficulties of working in a deep, narrow field jeopardize safety in surgical procedures, especially for less experienced surgeons have been described. Our systematic, step-by-step traction techniques on the skin, the pericardium, the right atrial appendage, the aortic root, both venae cavae, and the free wall of the right ventricular outflow, using a mechanical retractor and traction sutures, facilitate surgical field exposure and the achievement of safety. As described below, our procedures are simple, allow direct inspection, and assist those working toward technical mastery.

  16. Minimal Role of Basal Shear Tractions in Driving Nubia-Somalia Divergence Across the East African Rift System

    Stamps, D. S.; Calais, E.; Iaffaldano, G.; Flesch, L. M.


    The Nubian and Somalian plates actively diverge along the topographically high, ~5000 km long East African Rift System (EARS). As no major subduction zones bound Africa, one can assume that the forces driving the Nubia-Somalia plate system result primarily from mantle buoyancies and lateral variation in lithospheric gravitational potential energy. Images from seismic tomography and convection models suggest active mantle flow beneath Africa. However, the contribution from large-scale convection to the force balance driving plate divergence across the EARS remains in question. In this work we investigate the impact of mantle shear tractions on the dynamics of Nubia-Somalia divergence across the EARS. We compare surface motions inferred from GPS observations with strain rates and velocities predicted from dynamic models where basal shear stresses are (1) derived from forward mantle circulation models and (2) inferred from stress field boundary conditions that balance buoyancy forces in the African lithosphere. Upper mantle anisotropy derived from seismic observations beneath Africa provide independent constraints for the latter. Preliminary results suggest that basal shear tractions play a minor role in the dynamics of Nubia-Somalia divergence along the EARS. This result implies mantle-lithosphere decoupling, possibly promoted by a low viscosity asthenosphere. We corroborate the robustness of our results with estimates of upper mantle viscosity based on local upper mantle temperature estimates and rheological parameters obtained from laboratory experiments.

  17. 腰椎牵引的力的三要素探讨%Investigation on the three elements of the lumbar traction

    孙戴; 林德快; 林建强


    目的 探讨腰椎牵引力的三要素对腰椎间盘突出症患者康复的影响.方法 将160例行腰椎牵引的腰椎间盘突出的患者随机分成力量组、时间组和体位组,三组均采用钱璟康复器材有限公司生产的T-YZQ型牵引设备进行牵引治疗.力量组分成大、小剂量分别给予患者体重30%和60%的牵引力进行治疗;时间组分成长、短时间组,分别给予20和40min的时间进行治疗;体位组分成仰卧位、俯卧位组进行治疗.结果 体位组中,俯卧位牵引的疗效优于仰卧位,其余两组之间无明显差别.结论 根据患者的实际情况选择合适的时间、力量和体位,可优化物理治疗的效果.%Objective To investigate the effects of the three elements of the lumbar traction on the patients with the lumbar hemiated disc(LHD). Methods 160 patients with LHD given lumbar traction were randomly divided into force group,time group and posture group. AH groups used the traction equipment T-YXQ type produced by the QIANJING rehabilitation equipment ltd. The force group was divided into big force group and small force group,which given 30% and 60% of the Patient's body weight for lumbar traction respectively. Hie time group was divided into long time group and short time group,which given 20 min and 40 min of the lumbar traction respectively. The posture group was divided into supination group and prostration group. Results In posturegroup,the effect of traction in the prostration group was better than the supination group,while the rest two groups had no sensible difference. Conclusion According o the actual situation of patients, choosing the appropriate time,strength and postures can optimize physical therapy effect.


    M. O. Kostin


    Full Text Available A comparative characteristic of different concepts and expressions for determination of reactive power in the circuits with non-sinusoidal electric values has been given. For the first Ukrainian electric locomotives of DE1 type with the system of DC electric traction, the values of reactive power after Budeany, Fryze, and also the differential, integral and generalized reactive powers have been determined. Some measures on reducing its consumption by the DC electric rolling stock have been suggested.

  19. Modern Solutions for Automation of Electrical Traction Power Supply Systems

    Ana Mihaela Andreica


    Full Text Available This paper presents modern solutions for the automation of the electrical traction power supply system used in urban public transport (trams, trolleybuses and subway trains. The monitoring and control of this process uses SCADA distributed architectures, grouped around a central point (dispatcher who controls all field sensors, transmitters and actuators using programmable logical controllers. The presented applications refer to the Bucharest electrical transport infrastructure.

  20. Creation of electromechanical device for electric vehicle traction

    Денис Юрьевич Зубенко


    Full Text Available The problems of creation of electromechanical device for electric vehicle traction are considered in the article. The aim of creation this design are the replacement of the internal combustion engine on electromechanical device. For this electromechanical device are constructed model, which describe processes that occur in the electric drive of electromechanical device. Characteristics of the main modes of motion were recorded. The introduction of electromechanical device will reduce the level of emissions and reduce noise in the cities

  1. [Acupuncture combined with traction therapy for lumbar disc herniation: a systematic review].

    Li, Xiu-zhen; Chen, Hai-yong; Zheng, Xiao; Liu, Nong-yu


    To evaluate the efficacy and safety of acupuncture combined with traction therapy for lumbar disc herniation, providing the basis for future research strategies. Randomized control trials. (RCT) of acupuncture combined with traction therapy for lumber disc herniation at home and abroad from 2000 to 2013 were searched, analysis and evaluation of literature and strength of evidence were based on the principles and methods of Evidence-based Medicine. The total effective rate and curative rate were considered as primary outcome measures; pain improvement, quality of life, relapse rate and adverse effects were considered as secondary outcome measures. Seventeen RCTs were identified, Meta-analysis showed that (1) total effective rate and curative rate: acupuncture combined with traction therapy was better than single therapy (acupuncture or traction); (2) pain improvement: acupuncture combined with traction therapy was better than traction therapy; (3) relapse rate: current evidence could not support the conclusion that acupuncture combined with traction therapy was better than traction therapy. Acupuncture combined with traction therapy for lumbar disc herniation was effective. However, the included studies were with high risk of bias, important outcome measures such as quality of life, relapse rate and adverse effects were not found in most of the studies. Current evidence has not yet been able to fully reflect acupuncture combined with traction therapy for lumbar disc herniation is better than single therapy, so more RCTs of higher quality are needed to further confirm its efficacy and safety.

  2. Biomechanical analysis of two-step traction therapy in the lumbar spine.

    Park, Won Man; Kim, Kyungsoo; Kim, Yoon Hyuk


    Traction therapy is one of the most common conservative treatments for low back pain. However, the effects of traction therapy on lumbar spine biomechanics are not well known. We investigated biomechanical effects of two-step traction therapy, which consists of global axial traction and local decompression, on the lumbar spine using a validated three-dimensional finite element model of the lumbar spine. One-third of body weight was applied on the center of the L1 vertebra toward the superior direction for the first axial traction. Anterior translation of the L4 vertebra was considered as the second local decompression. The lordosis angle between the superior planes of the L1 vertebra and sacrum was 44.6° at baseline, 35.2° with global axial traction, and 46.4° with local decompression. The fibers of annulus fibrosus in the posterior region, and intertransverse and posterior longitudinal ligaments experienced stress primarily during global axial traction, these stresses decreased during local decompression. A combination of global axial traction and local decompression would be helpful for reducing tensile stress on the fibers of the annulus fibrosus and ligaments, and intradiscal pressure in traction therapy. This study could be used to develop a safer and more effective type of traction therapy.

  3. Effect of continuous lumbar traction on the size of herniated disc material in lumbar disc herniation.

    Ozturk, Bulent; Gunduz, Osman Hakan; Ozoran, Kursat; Bostanoglu, Sevinc


    We investigated the effects of continuous lumbar traction in patients with lumbar disc herniation on clinical findings, and size of the herniated disc measured by computed tomography (CT). In this prospective, randomized, controlled study, 46 patients with lumbar disc herniation were included, and randomized into two groups as the traction group (24 patients), and the control group (22 patients). The traction group was given a physical therapy program and continuous lumbar traction. The control group was given the same physical therapy program without traction, for the same duration of time. Data for the clinical symptoms and signs were collected before and after the treatment together with calculation of a herniation index, from the CT images that showed the size of the herniated disc material. In the traction group, most of the clinical findings significantly improved with treatment. Size of the herniated disc material in CT decreased significantly only in the traction group. In the traction group the herniation index decreased from 276.6+/-129.6 to 212.5+/-84.3 with treatment (p0.05). Patients with greater herniations tended to respond better to traction. In conclusion, lumbar traction is both effective in improving symptoms and clinical findings in patients with lumbar disc herniation and also in decreasing the size of the herniated disc material as measured by CT.

  4. Road dust from pavement wear and traction sanding

    Kupiainen, K.


    Vehicles affect the concentrations of ambient airborne particles through exhaust emissions, but particles are also formed in the mechanical processes in the tire-road interface, brakes, and engine. Particles deposited on or in the vicinity of the road may be re-entrained, or resuspended, into air through vehicle-induced turbulence and shearing stress of the tires. A commonly used term for these particles is 'road dust'. The processes affecting road dust emissions are complex and currently not well known. Road dust has been acknowledged as a dominant source of PM10 especially during spring in the sub-arctic urban areas, e.g. in Scandinavia, Finland, North America and Japan. The high proportion of road dust in sub-arctic regions of the world has been linked to the snowy winter conditions that make it necessary to use traction control methods. Traction control methods include dispersion of traction sand, melting of ice with brine solutions, and equipping the tires with either metal studs (studded winter tires), snow chains, or special tire design (friction tires). Several of these methods enhance the formation of mineral particles from pavement wear and/or from traction sand that accumulate in the road environment during winter. When snow and ice melt and surfaces dry out, traffic-induced turbulence makes some of the particles airborne. A general aim of this study was to study processes and factors underlying and affecting the formation and emissions of road dust from paved road surfaces. Special emphasis was placed on studying particle formation and sources during tire road interaction, especially when different applications of traction control, namely traction sanding and/or winter tires were in use. Respirable particles with aerodynamic diameter below 10 micrometers (PM10) have been the main concern, but other size ranges and particle size distributions were also studied. The following specific research questions were addressed: (i) How do traction

  5. Viscous erosion with a generalized traction integral equation

    Mitchell, William H


    A double-layer integral equation for the surface tractions on a body moving in a viscous fluid is derived, allowing for the incorporation of a background flow and/or the presence of a plane wall. The Lorentz reciprocal theorem is used to link the surface tractions on the body to integrals involving the background velocity and stress fields on an imaginary bounding sphere (or hemisphere for wall-bounded flows). The derivation requires the velocity and stress fields associated with numerous fundamental singularity solutions which we provide for free-space and wall-bounded domains. Two sample applications of the method are discussed: we study the tractions on an ellipsoid moving near a plane wall, which provides a more detailed understanding of the well-studied glancing and reversing trajectories, and we explore a new problem, erosion of bodies by a viscous flow, in which the surface is ablated at a rate proportional to the local viscous shear stress. Simulations and analytical estimates suggest that a spherical...

  6. Various approaches to the modelling of large scale 3-dimensional circulation in the Ocean

    Shaji, C.; Bahulayan, N.; Rao, A.D.; Dube, S.K.

    In this paper, the three different approaches to the modelling of large scale 3-dimensional flow in the ocean such as the diagnostic, semi-diagnostic (adaptation) and the prognostic are discussed in detail. Three-dimensional solutions are obtained...



    Focusing on the study of the components of mechanical rotational body,the data structure and algorithm of component model generation are discussed.Some problems in assembly process of 3-dimensional graph of components are studied in great detail.

  8. On an asymptotic distribution of dependent random variables on a 3-dimensional lattice.

    Harvey, Danielle J; Weng, Qian; Beckett, Laurel A


    We define conditions under which sums of dependent spatial data will be approximately normally distributed. A theorem on the asymptotic distribution of a sum of dependent random variables defined on a 3-dimensional lattice is presented. Examples are also presented.

  9. Dynamic in vivo 3-dimensional moment arms of the individual quadriceps components.

    Wilson, Nicole A; Sheehan, Frances T


    The purpose of this study was to provide the first in vivo 3-dimensional (3D) measures of knee extensor moment arms, measured during dynamic volitional activity. The hypothesis was that the vastus lateralis (VL) and vastus medialis (VM) have significant off-axis moment arms compared to the central quadriceps components. After obtaining informed consent, three 3D dynamic cine phase contrast (PC) MRI sets (x,y,z velocity and anatomic images) were acquired from 22 subjects during active knee flexion and extension. Using a sagittal-oblique and two coronal-oblique imaging planes, the origins and insertions of each quadriceps muscle were identified and tracked through each time frame by integrating the cine-PC velocity data. The moment arm (MA) and relative moment (RM, defined as the cross product of the tendon line-of-action and a line connecting the line-of-action with the patellar center of mass) were calculated for each quadriceps component. The tendencies of the VM and VL to produce patellar tilt were evenly balanced. Interestingly, the magnitude of RM-P(Spin) for the VM and VL is approximately four times greater than the magnitude of RM-P(Tilt) for the same muscles suggesting that patellar spin may play a more important role in patellofemoral kinematics than previously thought. Thus, a force imbalance that leads to excessive lateral tilt, such as VM weakness in patellofemoral pain syndrome, would produce excessive negative spin (positive spin: superior patellar pole rotates laterally) and to a much greater degree. This would explain the increased negative spin found in recent studies of patellar maltracking. Assessing the contribution of each quadriceps component in three dimensions provides a more complete understanding of muscle functionality.

  10. A Traction Three-Phase to Single-Phase Cascade Converter Substation in an Advanced Traction Power Supply System

    Xiaoqiong He


    Full Text Available The advanced traction power supply system (ATPSS is a new directional development for traction power supply systems, which can totally remove the neutral sections and effectively promote power quality. However, the existing converters suffer from small substation capacity. In this paper, a new configuration based on a three-level neutral point clamped (3L-NPC three-phase to single-phase cascade converter in a substation is proposed for ATPSS, which can be used to match the capacity of the converter for high voltage and large power applications. The control strategy of the proposed converter is analyzed in depth, and the phase disposition sinusoidal pulse width modulation (PD-SPWM with phase shift carrier SPWM (PSC-SPWM is employed in the inverters. Then, the inductance equalizing circuit is applied for the voltage balance on the DC-link. Besides, a LC filter circuit is designed to eliminate the double line-frequency ripple of DC voltage. Afterwards, a simulation model and an experimental prototype are developed, respectively. The simulation results show that the proposed converter in this paper can not only meet the requirements of voltage and capacity for the traction network, but also improve power quality. Finally, the experimental results verify the correctness and feasibility of the proposed control strategy.

  11. Simulation software for CRH2 and CRH3 traction driver systems based on SIMULINK and VC

    Qin-fen LU; Bin WANG; Xiao-yan HUANG; Ji-en MA; You-tong FANG; Jin YU; Wen-ping CAO


    Simulation models of traction driver systems were established using SIMULINK,according to the actual structure and parameters of China Railway High-Speed 2 (CRH2) and China Railway High-Speed 3 (CRH3) trains.In these models,the traction motor adopts transient current control and an indirect rotor magnetic field orientation vector control strategy,and the traction converter uses sinusoidal pulse width modulation (SPWM) and space vector pulse width modulation (SVPWM) methods.After these models are transformed in VC++ program,and a friendly interface and data processing system are constructed.simulation software is obtained for CRH2 and CRH3 traction driver systems.On this basis,the operational performance of a traction converter was simulated and analyzed at different train speeds and in different conditions.The simulation results can provide a reference for the actual design and production of a traction converter.

  12. The investigation of reverse traction current influence on tone track circuit modes



    Full Text Available Introduction: With the introduction of high-speed traffic there is an increased consumption of traction current by new types of rolling stock. This issue is important, as high levels of traction currents can have not only prevents, but also a dangerous impact on the equipment of railway automation devices. It is necessary to investigate the propagation of traction currents and potentials along the rails. Objective: Investigate the propagation of traction currents and potentials along the rails, the determination of critical currents, which not executed tone track circuits modes. Methods: In order to investigate the mathematical model, and the method of calculation tone track circuits modes was used. Results: By means of mathematical model, which includes being several rolling-stocks at the feeder zone, different rail resistance and isolation, the diagrams of currents and potentials propagations for DC and AC electric traction have been obtained. A comparative analysis of the experimental data and the results of the investigation has been realized. Based on received levels of reverse traction current their influence on track circuit modes has been investigated. Conclusions: The reverse traction current level near the substation and rolling-stock can be more than 600A. Great reverse traction current levels have an influence on tonal track circuit functioning, namely normal and shunt modes. When the traction current arrives 200 A there is a reduction criteria of tonal track circuits.

  13. FreedomCAR Advanced Traction Drive Motor Development Phase I

    Ley, Josh (UQM Technologies, Inc.); Lutz, Jon (UQM Technologies, Inc.)


    The overall objective of this program is to design and develop an advanced traction motor that will meet the FreedomCAR and Vehicle Technologies (FCVT) 2010 goals and the traction motor technical targets. The motor specifications are given in Section 1.3. Other goals of the program include providing a cost study to ensure the motor can be developed within the cost targets needed for the automotive industry. The program has focused on using materials that are both high performance and low costs such that the performance can be met and cost targets are achieved. In addition, the motor technologies and machine design features must be compatible with high volume manufacturing and able to provide high reliability, efficiency, and ruggedness while simultaneously reducing weight and volume. Weight and volume reduction will become a major factor in reducing cost, material cost being the most significant part of manufacturing cost at high volume. Many motor technology categories have been considered in the past and present for traction drive applications, including: brushed direct current (DC), PM (PM) brushless dc (BLDC), alternating current (AC) induction, switched reluctance and synchronous reluctance machines. Of these machine technologies, PM BLDC has consistently demonstrated an advantage in terms of power density and efficiency. As rare earth magnet cost has declined, total cost may also be reduced over the other technologies. Of the many different configurations of PM BLDC machines, those which incorporate power production utilizing both magnetic torque as well as reluctance torque appear to have the most promise for traction applications. There are many different PM BLDC machine configurations which employ both of these torque producing mechanisms; however, most would fall into one of two categories--some use weaker magnets and rely more heavily on reluctance torque (reluctance-dominant PM machines), others use strong PMs and supplement with reluctance torque

  14. Model-based efficiency evaluation of combine harvester traction drives

    Steffen Häberle


    Full Text Available As part of the research the drive train of the combine harvesters is investigated in detail. The focus on load and power distribution, energy consumption and usage distribution are explicitly explored on two test machines. Based on the lessons learned during field operations, model-based studies of energy saving potential in the traction train of combine harvesters can now be quantified. Beyond that the virtual machine trial provides an opportunity to compare innovative drivetrain architectures and control solutions under reproducible conditions. As a result, an evaluation method is presented and generically used to draw comparisons under local representative operating conditions.

  15. Control algorithms for single inverter dual induction motor system applied to railway traction; Commande algorithmique d'un systeme mono-onduleur bimachine asynchrone destine a la traction ferroviaire

    Pena Eguiluz, R.


    The goal of this work concerns the modelling and the behaviour characterisation of a single inverter dual induction motor system applied to a railway traction bogie (BB36000) in order to concept its control. First part of this job is dedicated to the detailed description of overall system. The influence analysis of the internal perturbations (motor parameters variation) and, external perturbations (pantograph detachment, adherence loss, stick-slip) of the system have made considering the field oriented control applied to each motor of the bogie (classical traction structure). vi In a second part, a novel propulsion structure is proposed. It is composed by a single pulse-width modulated two level voltage source inverter. It supplies two parallel connected induction motors, which generate the transmitted traction force to the bogie wheels. The locomotive case represents the common load for the two motors. Several co-operative control strategies (CS) are studied. They are: the mean CS, the double mean CS, the master - slave switched CS and, the mean differential CS. In addition, an appropriated electric modes observer structure for these different controls has studied. These controls have validated applying the perturbations to the models using the solver SABER. This special approach is equivalent to quasi-experimentation, because the mechanical and the electrical system components have modelled using MAST language and, the sample control has created by a C code programme in the SABER environment. Third part is dedicated to the mechanical sensor suppression and, its adaptation in the cooperative control strategies. The partial speed reconstruction methods are: the fundamental frequency relation, the mechanical Kalman filter, the variable structure observer and the MRAS. Finally, the hardware system configuration of the experimental realisation is described. (author)

  16. The 3-Dimensional q-Deformed Harmonic Oscillator and Magic Numbers of Alkali Metal Clusters

    Bonatsos, Dennis; Raychev, P P; Roussev, R P; Terziev, P A; Bonatsos, Dennis


    Magic numbers predicted by a 3-dimensional q-deformed harmonic oscillator with Uq(3) > SOq(3) symmetry are compared to experimental data for alkali metal clusters, as well as to theoretical predictions of jellium models, Woods--Saxon and wine bottle potentials, and to the classification scheme using the 3n+l pseudo quantum number. The 3-dimensional q-deformed harmonic oscillator correctly predicts all experimentally observed magic numbers up to 1500 (which is the expected limit of validity for theories based on the filling of electronic shells), thus indicating that Uq(3), which is a nonlinear extension of the U(3) symmetry of the spherical (3-dimensional isotropic) harmonic oscillator, is a good candidate for being the symmetry of systems of alkali metal clusters.

  17. Initial displacements and variations of eight human child skulls owing to high-pull headgear traction determined with laser holography.

    Kragt, G; Duterloo, H S; Algra, A M


    In this study eight macerated, human child skulls (dental age approximately 9.5 years) were subjected to a standardized high-pull headgear traction system. Tensile forces from 0.5 to 3.5 N (1 N = 0.1 kgf) per side were produced to the maxillae. Displacements of skeletal components were determined at 22 indicator points per skull by means of laser holography. Coordinated displacements and variations in amount and direction were established in all skulls. The overall amount of displacements was primarily a characteristic of an individual skull, not of a particular displacement. On the average, the maxillae were displaced in a slightly downward and posterior direction almost parallel to the occlusal plane. No deformations of skeletal components were seen. Results indicated that initial displacements of the maxillae and other skeletal components are not in the same direction as the direction of applied forces.

  18. 3-dimensional echocardiography and its role in preoperative mitral valve evaluation.

    Andrawes, Michael N; Feinman, Jared W


    Echocardiography plays a key role in the preoperative evaluation of mitral valve disease. 3-dimensional echocardiography is a relatively new development that is being used more and more frequently in the evaluation of these patients. This article reviews the available literature comparing the use of this new technology to classic techniques in the assessment of mitral valve pathology. The authors also review some of the novel insights learned from 3-dimensional echocardiography and how they may be used in surgical decision making and planning.

  19. Regenerative material for aneurysm embolization A 3-dimensional culture system of fibroblasts and calcium alginate gel

    Jingdong Zhang; Kan Xu; Jinlu Yu; Jun Wang; Qi Luo


    Calcium alginate gel (CAG) has been shown to successfully model aneurysm embolization within a short period of time. However, gradually degrading CAG potentially results in aneurysm recanalization.In the present study, a regenerative embolic material was designed by seeding rat fibroblasts in a CAG. The study investigated the feasibility of constructing a 3-dimensional culture system. The fibroblasts grew well and firmly attached to the CAG. CAG was conducive for fibroblast growth, and resulted in a 3-dimensional culture system. Results show that CAG can be used theoretically as a vascular, regenerative, embolic material.

  20. Fatigue behavior of carbon/epoxy composites reinforced with 3-Dimensional woven fabric

    Mehmet Karahan


    Full Text Available This paper reports results of study of fatigue behavior of a non-crimp 3-dimensional woven carbon/epoxy composite in tension-tension fatigue. Infinite fatigue life limit corresponds to the load of 27.5 kN for fill direction. The damage under fatigue loading starts and develops from intersection of z-yarns and fill yarns. Since the z-yarns bonded the yarn layers, it is not seen the delaminastion damages. This indicate that for load carrying capacity and stiffness of 3-dimensional composites better than classic 2-dimensional textile composites.

  1. Changes in dynamics processes of the muscles’ traction under influence of stress-factors

    D. M. Nozdrenko


    Full Text Available Change of fibers’ dynamic parameters of the frog Rana temporaria skeletal muscle m. tibialis traction under influence of modulated stimulation and aluminium chloride solutions was studied. At 10-4,5·10-4 and 10‑3 M·l-1 concentrations of aluminium chloride the nonlinear decrease of the muscle fibers’ traction parameters was observed.

  2. Bilateral Vitreopapillary Traction Demonstrated by Optical Coherence Tomography Mistaken for Papilledema

    Elizabeth Houle


    Full Text Available Purpose. The purpose of this study was to report a case of bilateral vitreopapillary traction, previously misdiagnosed as papilledema. Methods. A case report is presented of a 47-year-old woman with a prior diagnosis of papilledema, who is shown to have bilateral vitreopapillary traction rather than true optic disc swelling, confirmed by optical coherence tomography (OCT. Results. OCT showed vitreous traction surrounding the optic discs of both eyes. Fluorescein angiography demonstrated focal leakage of both discs. Conclusion. Bilateral disc elevation caused by vitreous traction can be confused with papilledema. In such cases, OCT can be used to arrive at the correct diagnosis. Although the phenomenon of vitreopapillary traction is well reported, this case indicates that not all ophthalmologists recognize the condition.

  3. 3-dimensional orthodontics visualization system with dental study models and orthopantomograms

    Zhang, Hua; Ong, S. H.; Foong, K. W. C.; Dhar, T.


    The aim of this study is to develop a system that provides 3-dimensional visualization of orthodontic treatments. Dental plaster models and corresponding orthopantomogram (dental panoramic tomogram) are first digitized and fed into the system. A semi-auto segmentation technique is applied to the plaster models to detect the dental arches, tooth interstices and gum margins, which are used to extract individual crown models. 3-dimensional representation of roots, generated by deforming generic tooth models with orthopantomogram using radial basis functions, is attached to corresponding crowns to enable visualization of complete teeth. An optional algorithm to close the gaps between deformed roots and actual crowns by using multi-quadratic radial basis functions is also presented, which is capable of generating smooth mesh representation of complete 3-dimensional teeth. User interface is carefully designed to achieve a flexible system with as much user friendliness as possible. Manual calibration and correction is possible throughout the data processing steps to compensate occasional misbehaviors of automatic procedures. By allowing the users to move and re-arrange individual teeth (with their roots) on a full dentition, this orthodontic visualization system provides an easy and accurate way of simulation and planning of orthodontic treatment. Its capability of presenting 3-dimensional root information with only study models and orthopantomogram is especially useful for patients who do not undergo CT scanning, which is not a routine procedure in most orthodontic cases.

  4. 3-Dimensional and Interactive Istanbul University Virtual Laboratory Based on Active Learning Methods

    Ince, Elif; Kirbaslar, Fatma Gulay; Yolcu, Ergun; Aslan, Ayse Esra; Kayacan, Zeynep Cigdem; Alkan Olsson, Johanna; Akbasli, Ayse Ceylan; Aytekin, Mesut; Bauer, Thomas; Charalambis, Dimitris; Gunes, Zeliha Ozsoy; Kandemir, Ceyhan; Sari, Umit; Turkoglu, Suleyman; Yaman, Yavuz; Yolcu, Ozgu


    The purpose of this study is to develop a 3-dimensional interactive multi-user and multi-admin IUVIRLAB featuring active learning methods and techniques for university students and to introduce the Virtual Laboratory of Istanbul University and to show effects of IUVIRLAB on students' attitudes on communication skills and IUVIRLAB. Although…

  5. On Maximal Surfaces in Certain Non-Flat 3-Dimensional Robertson-Walker Spacetimes

    Romero, Alfonso, E-mail: [Universidad de Granada, Departamento de Geometria y Topologia (Spain); Rubio, Rafael M., E-mail: [Universidad de Cordoba, Departamento de Matematicas, Campus de Rabanales (Spain)


    An upper bound for the integral, on a geodesic disc, of the squared length of the gradient of a distinguished function on any maximal surface in certain non-flat 3-dimensional Robertson-Walker spacetimes is obtained. As an application, a new proof of a known Calabi-Bernstein's theorem is given.

  6. 3-Dimensional Cahn-Hilliard Equation with Concentration Dependent Mobility and Gradient Dependent Potential

    Rui HUANG; Yang CAO


    In this paper we investigate the initial boundary value problem of Cahn-Hilliard equation with concentration dependent mobility and gradient dependent potential. By the energy method and the theory of Campanato spaces, we prove the existence and the uniqueness of classical solutions in 3-dimensional space.

  7. Design of Biphasic Polymeric 3-Dimensional Fiber Deposited Scaffolds for Cartilage Tissue Engineering Applications

    Moroni, L.; Hendriks, J.A.A.; Schotel, R.; Wijn, de J.R.; Blitterswijk, van C.A.


    This report describes a novel system to create rapid prototyped 3-dimensional (3D) fibrous scaffolds with a shell-core fiber architecture in which the core polymer supplies the mechanical properties and the shell polymer acts as a coating providing the desired physicochemical surface properties. Pol

  8. Reproducibility of a 3-dimensional gyroscope in measuring shoulder anteflexion and abduction

    Penning, L.I.F.; Guldemond, N.A.; De Bie, R.A.; Walenkamp, G.H.I.M.


    Background: Few studies have investigated the use of a 3-dimensional gyroscope for measuring the range of motion (ROM) in the impaired shoulder. Reproducibility of digital inclinometer and visual estimation is poor. This study aims to investigate the reproducibility of a tri axial gyroscope in measu

  9. Full 3-dimensional digital workflow for multicomponent dental appliances : A proof of concept

    van der Meer, W. Joerd; Vissink, Arjan; Ren, Yijin


    BACKGROUND: The authors used a 3-dimensional (3D) printer and a bending robot to produce a multicomponent dental appliance to assess whether 3D digital models of the dentition are applicable for a full digital workflow. METHODS: The authors scanned a volunteer's dentition with an intraoral scanner (

  10. An application of the 3-dimensional q-deformed harmonic oscillator to the nuclear shell model

    Raychev, P P; Lo-Iudice, N; Terziev, P A


    An analysis of the construction of a q-deformed version of the 3-dimensional harmonic oscillator, which is based on the application of q-deformed algebras, is presented. The results together with their applicability to the shell model are compared with the predictions of the modified harmonic oscillator.

  11. Full 3-dimensional digital workflow for multicomponent dental appliances A proof of concept

    Meer, van der Joerd; Vissink, Arjan; Ren, Yijin


    Background. The authors used a 3-dimensional (3D) printer and a bending robot to produce a multicomponent dental appliance to assess whether 3D digital models of the dentition are applicable for a full digital workflow. Methods. The authors scanned a volunteer's dentition with an intraoral scanner (

  12. On an asymptotic distribution of dependent random variables on a 3-dimensional lattice✩

    Harvey, Danielle J.; Weng, Qian; Beckett, Laurel A.


    We define conditions under which sums of dependent spatial data will be approximately normally distributed. A theorem on the asymptotic distribution of a sum of dependent random variables defined on a 3-dimensional lattice is presented. Examples are also presented. PMID:20436940

  13. Estimating 3-Dimensional Structure of Tropical Forests from Radar Interferometry / Estimativa da Estrutura 3-Dimensional das Florestas Tropicais Através de Interferometria de Radar

    Robert Treuhaft


    Full Text Available This paper describes the retrieval of 3-dimensional vegetation density profiles from interferometric synthetic aperture radar (InSAR using physical models. InSAR’s sensitivity to vertical structure is generally regarded as less direct and more difficult to understand than that of lidar. But InSAR’s coverage is superior to that of lidar, suggesting InSAR is more promising as an important component of a global 3-dimensional forest monitoring technique. The goal of this paper is to introduce, simplify and demystify the use of simple physical models to understand InSAR. A general equation expressing the InSAR observation in terms of density is described heuristically, along with the approximations in its development. The information content of the equation leads to the estimation of density parameters. Preliminary results are shown from a multibaseline C-band (wavelength=0.056 m vertical-polarization interferometer, realized with AirSAR flown at multiple altitudes over primary, secondary, and selectively logged tropical forests, as well as abandoned pastures at La Selva Biological Station in Costa Rica.

  14. Topological entropy and renormalization group flow in 3-dimensional spherical spaces

    Asorey, M. [Departamento de Física Teórica, Universidad de Zaragoza,E-50009 Zaragoza (Spain); Beneventano, C.G. [Departamento de Física, Universidad Nacional de La Plata,Instituto de Física de La Plata, CONICET-Universidad Nacional de La Plata,C.C. 67, 1900 La Plata (Argentina); Cavero-Peláez, I. [Departamento de Física Teórica, Universidad de Zaragoza,E-50009 Zaragoza (Spain); CUD,E-50090, Zaragoza (Spain); D’Ascanio, D.; Santangelo, E.M. [Departamento de Física, Universidad Nacional de La Plata,Instituto de Física de La Plata, CONICET-Universidad Nacional de La Plata,C.C. 67, 1900 La Plata (Argentina)


    We analyze the renormalization group (RG) flow of the temperature independent term of the entropy in the high temperature limit β/a≪1 of a massive field theory in 3-dimensional spherical spaces, M{sub 3}, with constant curvature 6/a{sup 2}. For masses lower than ((2π)/β), this term can be identified with the free energy of the same theory on M{sub 3} considered as a 3-dimensional Euclidean space-time. The non-extensive part of this free energy, S{sub hol}, is generated by the holonomy of the spatial metric connection. We show that for homogeneous spherical spaces the holonomy entropy S{sub hol} decreases monotonically when the RG scale flows to the infrared. At the conformal fixed points the values of the holonomy entropy do coincide with the genuine topological entropies recently introduced. The monotonic behavior of the RG flow leads to an inequality between the topological entropies of the conformal field theories connected by such flow, i.e. S{sub top}{sup UV}>S{sub top}{sup IR}. From a 3-dimensional viewpoint the same term arises in the 3-dimensional Euclidean effective action and has the same monotonic behavior under the RG group flow. We conjecture that such monotonic behavior is generic, which would give rise to a 3-dimensional generalization of the c-theorem, along the lines of the 2-dimensional c-theorem and the 4-dimensional a-theorem. The conjecture is related to recent formulations of the F-theorem. In particular, the holonomy entropy on lens spaces is directly related to the topological Rényi entanglement entropy on disks of 2-dimensional flat spaces.

  15. Nascent Focal Adhesions Are Responsible for the Generation of Strong Propulsive Forces in Migrating Fibroblasts


    Fibroblast migration involves complex mechanical interactions with the underlying substrate. Although tight substrate contact at focal adhesions has been studied for decades, the role of focal adhesions in force transduction remains unclear. To address this question, we have mapped traction stress generated by fibroblasts expressing green fluorescent protein (GFP)-zyxin. Surprisingly, the overall distribution of focal adhesions only partially resembles the distribution of traction stress. In ...

  16. 直供方式下牵引变电所轨地回流研究%Research on Return Current to Traction Substation of TRNF Traction Network

    李良威; 楚振宇; 邓云川


    Research purposes; The real tests and simulation analysis were made for the return current to the traction substation of TRNF traction network for passenger dedicated line to know the regulation of the traction return current to the traction substation of the TRNF traction network for guiding the design work. Research conclusions:This paper analyzes the principle of the traction return system of TRNF traction network. From the simulation calculation and analysis of the tested data of the return current to the Chongshan substation of the TRNF traction network with return wire for the Chengdu - Dujiangyan Passenger Dedicated Line, it can be seen using the TRNF traction network with return wire can significantly improve the distribution form of the return current system, reduce the proportion of the return current of the rail - earth and cut the impacts on the traction power supply equipment and communications signals equipments. Thus it can provide the design basis for selection of the equipments for the substation and communications signaling systems.%研究目的:通过对客运专线采用的带回流线的直供方式下牵引变电所轨地回流的实测和仿真分析,对牵引变电所处牵引回流规律获得认识,有利于指导设计工作.研究结论:本文分析了直供方式下牵引回流系统的原理,针对新建客运专线成都至都江堰铁路采用的带回流线的直供方式,通过对崇山变电所轨地回流系统的仿真计算和实测数据分析,得出采用带回流线的直供方式,可以明显改善回流系统的分配方式,减少轨地回流所占的比例,降低对牵引供电设备和通信信号设备的影响,并由此可以为牵引供变电和信号系统的设备选型提供设计依据.

  17. The Fault Interpretation and Maintenance of the Traction Drive System for CRH5 Multiple-unit Train%CRH5型动车组牵引传动系统故障解析及维护保养



    动车组传动系统为动车组的动力传输装置,CRH5型动车组牵引传动装置区别于其他高速动车组传动系统,独具特点。CRH5型动车组牵引传动系统由牵引电机、万向轴、齿轮箱三大部件组成。牵引电机产生的牵引力通过万向轴及齿轮箱传导至车轮上,最终产生了牵引作用。本文通过牵引系统常见故障的分析,研究出可行性的预防方法,可以有效地规避动车组运行风险。%The drive system is the power transfer unit for multi-ple-unit trains. The traction drive system of CRH5 multiple-unit train differs from the drive system of other multiple-unit trains and has its own features. The traction and drive system of CRH5 multiple-unit train consists of such three major parts as traction motor, cardan shaft and gear case. The tractive force produced by the traction motor is transferred to the wheels through the cardan shaft and gear case, finally generating the function of traction. By analyzing common faults in the traction system, this paper studies feasible prevention methods which can effectively avoid the risks in the working of multiple-unit trains.

  18. Single-incision laparoscopic splenectomy with innovative gastric traction suture

    Srikanth G


    Full Text Available Laparoscopic splenectomy is now the gold standard for patients with idiopathic thrombocytopenic purpura (ITP undergoing splenectomy. There are a few reports in literature on single-incision laparoscopic (SIL splenectomy. Herein, we describe a patient undergoing SIL splenectomy for ITP without the use of a disposable port device. We report a 20-year-old female patient with steroid-refractory ITP having a platelet count of 14,000/cmm who underwent a SIL splenectomy. Dissection was facilitated by the use of a single articulating grasper and a gastric traction suture and splenic vessels were secured at the hilum with an endo-GIA stapler. She made an uneventful postoperative recovery and was discharged on the second postoperative day. She is doing well with no visible scar at 8-month follow-up.

  19. Novel Transverse Flux Machine for Vehicle Traction Applications: Preprint

    Wan, Z.; Ahmed, A.; Husain, I.; Muljadi, E.


    A novel transverse flux machine topology for electric vehicle traction applications using ferrite magnets is presented in this paper. The proposed transverse flux topology utilizes novel magnet arrangements in the rotor that are similar to the Halbach array to boost flux linkage; on the stator side, cores are alternately arranged around a pair of ring windings in each phase to make use of the entire rotor flux that eliminates end windings. Analytical design considerations and finite-element methods are used for an optimized design of a scooter in-wheel motor. Simulation results from finite element analysis (FEA) show that the motor achieved comparable torque density to conventional rare-earth permanent magnet (PM) machines. This machine is a viable candidate for direct-drive applications with low cost and high torque density.

  20. Brachial plexus injury: the London experience with supraclavicular traction lesions.

    Birch, Rolfe


    In this article, the author details the experiences of his hospital and other London hospitals in treating brachial plexus injury. As noted, important advances have been made in methods of diagnosis and repair. Myelography was replaced by CT scan and later by MRI. Among the topics the author explores are diagnosis (including pain, the presence or absence of the Tinel sign, and the irradiation of pins and needles) and the principles of repair. The author emphasizes that it is imperative that ruptured nerves be repaired as soon as possible, with the closed traction lesion coming, in urgency, close behind reattachment of the amputated hand or repair of a great artery and a trunk nerve in the combined lesion. Finally, the article concludes that the surgeon must be actively engaged in the whole process of rehabilitation and treatment of pain. This is part of a Point-Counterpoint discussion with Dr. David G. Kline's presentation of "A Personal Experience."

  1. Initial experience with ocriplasmin in the treatment of vitreomacular traction

    José Maurício Botto de Barros Garcia


    Full Text Available ABSTRACT This study aimed to report the clinical and structural outcomes of intravitreal ocriplasmin in the treatment of vitreomacular interface disorders in two tertiary centers in Brazil. A retrospective study was performed by reviewing medical records and spectral domain optical coherence tomography (SD-OCT findings of seven patients who were treated with a single ocriplasmin injection. A total of 57.14% of patients achieved resolution of vitreomacular traction as evidenced by SD-OCT. Regarding our functional results, 87.71% maintained or improved visual acuity after follow-up. To the best of our knowledge, this is the first study reporting initial results of ocriplasmin therapy in Brazil.

  2. Halo Gravity Traction Is Associated with Reduced Bone Mineral Density of Patients with Severe Kyphoscoliosis

    Xiao Han


    Full Text Available Background. Halo gravity traction (HGT is one of the most commonly used perioperative techniques for the treatment of severe kyphoscoliosis. This study was to explore the influence of HGT on the BMD of these patients. Methods. Patients with severe kyphoscoliosis treated by preoperative HGT for at least 2 months were included. Patients’ BMD were assessed by dual-energy X-ray absorptiometry at lumbar spine (LS, L2–L4 and femur neck (FN of the nondominant side. The weight and duration of traction, as well as baseline characteristics, were recorded. Results. Twenty patients were recruited. The average traction duration was 77.9±13.0 days while the mean traction weight was 39.9%±11.1% of total body weight. Remarkable decrease of BMD was observed at LS of 17 (85% patients and at FN of 18 (90% patients. After HGT, 75% of patients were found to have osteoporosis, the incidence of which was significantly higher than that before HGT (35%. The correlation analysis revealed BMD reduction was only significantly correlated with the traction duration. Conclusions. The current study showed that preoperative HGT can have obvious impact on the BMD. The BMD reduction is associated with traction duration, suggesting that long traction duration may bring more bone mineral loss.

  3. [The effect of halo-gravity traction in the preoperative treatment of neuromuscular scoliosis].

    Flierl, S; Carstens, C


    The purpose of this study is to evaluate the influence of halo-gravity-traction on paralytic scoliosis in various neurologic diseases. Between 1980 and 1993 preoperative halo-gravity-traction was applied in 32 patients with paralytic scoliosis (23 patients with myelomeningocele, 6 patients with poliomyelitis, 3 patients with cerebral palsy). In the myelomeningocele group the average curvature before treatment was 97.8 degrees, after surgery 45.1 degrees; which is an improvement of 53.9%. Halo-gravity-traction accounted for 12.8% improvement. In the poliomyelitis group the average curvature before treatment was 104.3 degrees, after surgery 58.0 degrees; which is an improvement of 44.4%. Halo-gravity-traction accounted for 16.9% improvement. In the cerebral palsy group the average curvature before treatment was 75.0 degrees, after surgery 39.0 degrees; which is an improvement of 48.0%. Halo-gravity-traction accounted for -2.7% improvement. If there is an effect the question remains, whether this will have consequences for the surgical outcome. The comparison between good and bad responders with the surgical result shows, that this result is independent of the halo-gravity-traction. From this results we draw the conclusion, that preoperative halo-gravity-traction can not be recommended in paralytic scoliosis.

  4. Analysis of electromyographic activities of the lumbar erector spinae caused by inversion traction.

    Kim, Chung Yoo; Kang, Jong Ho


    [Purpose] The purpose of this study was to analyze changes in the electromyographic activities of the lumbar erector spinae caused by inversion traction in order to verify the relaxation effect. [Subjects and Methods] The subjects included 60 healthy male adults who were equally and randomly assigned to a 30-30° group, a 30-60° group, and a 60-60° group. Inversion traction was performed for six minutes, and the electromyographic activities of the lumbar erector spinae (L2, L4) were measured before and after inversion traction. [Results] The root mean square values at the L2 and L4 levels on both sides were statistically significantly higher after inversion traction compared with before inversion traction. Before inversion traction, the root mean square values at the L2 and L4 levels on both sides in the 30-60° group and 60-60° group were significantly higher than those in the 30-30° group, while the root mean square values at the L2 and L4 levels on both sides showed no significant differences between the groups before inversion traction. [Conclusion] The findings of this study indicated that IT is more likely to elicits an increase in muscle tension and prevent relaxation of the lumbar erector spinae.


    I.V. Domanskyi


    Full Text Available The paper presents a systematic analysis of existing methods of reactive power compensation. The study of operating modes of the systems external and traction power supply is carried out. The methodology for selecting promising compensation schemes and energy-saving in the traction networks AC electrified railway lines is offered. The comparative evaluation of prospective controlled compensation devices shows that use of seamlessly adjustable devices with unregulated condensing the battery and with parallel translator regulated with thyristor unit and with filters to reduce harmonics bond to the large capital investments. For traction networks of domestic railways payback period is more than 10-15 years. The most promising for traction power supply today is a stepwise adjustable devices of reactive power compensation. For the efficient allocation of investments in programs and projects of modernization of system traction power supply developed by the methodology of selecting parameters and places placement devices transverse compensation in the system traction power supply, which is based on the use of software systems with imitation of interconnected instant circuits moving loads of electric rolling stock. Based on the results of multiple calculations full factor experiment when simulating work of the systems traction power supply during the day marked the most influencing factors on energy-saving in process freight on electric traction and established the extent of their influence. These include the overflows of power, the resistance of traction network, reactive power compensation, power supply circuits and the organization of trains. Innovative technologies energy-saving railways from positions of consideration their close connection with the systems external power supply are proposed.

  6. Surgical management of retinal diseases: proliferative diabetic retinopathy and traction retinal detachment.

    Cruz-Iñigo, Yousef J; Acabá, Luis A; Berrocal, Maria H


    Current indications for pars plana vitrectomy in patients with proliferative diabetic retinopathy (PDR) include vitreous hemorrhage, tractional retinal detachment (TRD), combined tractional and rhegmatogenous retinal detachment (CTRRD), diabetic macular edema associated with posterior hyaloidal traction, and anterior segment neovascularization with media opacities. This chapter will review the indications, surgical objectives, adjunctive pharmacotherapy, microincision surgical techniques, and outcomes of diabetic vitrectomy for PDR, TRD, and CTRRD. With the availability of new microincision vitrectomy technology, wide-angle microscope viewing systems, and pharmacologic agents, vitrectomy can improve visual acuity and achieve long-term anatomic stability in eyes with severe complications from PDR.

  7. 3-dimensional slope stability analyses using non-associative stress-strain relationships

    CHEN ZuYu; SUN Ping; WANG YuJie; ZHANG HongTao


    The research work presented in this paper refers to a new slope stability analysis method used for landslide risk evaluations. It is an extension of the 3-dimensional upper-bound slope stability analysis method proposed by Chen et sl. in 2001, which employs the Mohr-Coulomb's associative flow rule. It has been found that in a 3-dimensional area, a prism may not be able to move at friction angles to all its surrounding interfaces, as required by this associative rule, and convergence problems may occa-sionally arise. The new method establishes two velocity fields: (i) The plastic one that represents a non-associative and the best representative dilation behavior, and (ii) the virtual one that permits the solution for factor of safety in the work and energy balance equation. The new method can then allow any input value of dilation angle and thus solve the convergence problem. A practical application to a concrete dam foundation is illustrated.

  8. Zeeman-Tomography of the Solar Photosphere -- 3-Dimensional Surface Structures Retrieved from Hinode Observations

    Carroll, T A


    AIMS :The thermodynamic and magnetic field structure of the solar photosphere is analyzed by means of a novel 3-dimensional spectropolarimetric inversion and reconstruction technique. METHODS : On the basis of high-resolution, mixed-polarity magnetoconvection simulations, we used an artificial neural network (ANN) model to approximate the nonlinear inverse mapping between synthesized Stokes spectra and the underlying stratification of atmospheric parameters like temperature, line-of-sight (LOS) velocity and LOS magnetic field. This approach not only allows us to incorporate more reliable physics into the inversion process, it also enables the inversion on an absolute geometrical height scale, which allows the subsequent combination of individual line-of-sight stratifications to obtain a complete 3-dimensional reconstruction (tomography) of the observed area. RESULTS : The magnetoconvection simulation data, as well as the ANN inversion, have been properly processed to be applicable to spectropolarimetric obser...

  9. 3-Dimensional analysis for class III malocclusion patients with facial asymmetry


    Objectives The aim of this study is to investigate the correlation between 2-dimensional (2D) cephalometric measurement and 3-dimensional (3D) cone beam computed tomography (CBCT) measurement, and to evaluate the availability of 3D analysis for asymmetry patients. Materials and Methods A total of Twenty-seven patients were evaluated for facial asymmetry by photograph and cephalometric radiograph, and CBCT. The 14 measurements values were evaluated and those for 2D and 3D were compared. The pa...


    K.T.Joseph; Manas R. Sahoo


    The 3-dimensional zero-pressure gas dynamics system appears in the modeling for the large scale structure formation in the universe.The aim of this paper is to construct spherically symmetric solutions to the system.The radial component of the velocity and density satisfy a simpler one dimensional problem.First we construct explicit solutions of this one dimensional case with initial and boundary conditions.Then we get special radial solutions with different behaviours at the origin.

  11. On the structure of 3-dimensional 2-body problem solutions in Wheeler-Feynman electrodynamics

    Klimenko, S. [Institute for High Energy Physics, Protvino (Russian Federation); Nikitin, I. [National Research Center for Information Technology, St. Augustin (Germany)


    The problem of the relativistic 3-dimensional motion of 2 oppositely charged equally massive particles in classical electrodynamics with half-retarded/half-advanced interactions is investigated. It is shown that at a certain critical energy value the topological structure of phase space is changed, leading to bifurcation (splitting) of solutions, appearance of extra non-Newtonian degrees of freedom and break of reflectional symmetries.

  12. Energy Sources of the Dominant Frequency Dependent 3-dimensional Atmospheric Modes

    Schubert, S.


    The energy sources and sinks associated with the zonally asymmetric winter mean flow are investigated as part of an on-going study of atmospheric variability. Distinctly different horizontal structures for the long, intermediate and short time scale atmospheric variations were noted. In previous observations, the 3-dimensional structure of the fluctuations is investigated and the relative roles of barotropic and baroclinic terms are assessed.



    A 3-dimensional type-K competitive Lotka-Volterra system is considered in this paper. Two discretization schemes are applied to the system with an positive interior fixed point, and two corresponding discrete systems are obtained. By analyzing the local dynamics of the corresponding discrete system near the interior fixed point, it is showed that this system is not dynamically consistent with the continuous counterpart system.

  14. Cultivation of human neural progenitor cells in a 3-dimensional self-assembling peptide hydrogel.

    Liedmann, Andrea; Rolfs, Arndt; Frech, Moritz J


    The influence of 3-dimensional (3D) scaffolds on growth, proliferation and finally neuronal differentiation is of great interest in order to find new methods for cell-based and standardised therapies in neurological disorders or neurodegenerative diseases. 3D structures are expected to provide an environment much closer to the in vivo situation than 2D cultures. In the context of regenerative medicine, the combination of biomaterial scaffolds with neural stem and progenitor cells holds great promise as a therapeutic tool. Culture systems emulating a three dimensional environment have been shown to influence proliferation and differentiation in different types of stem and progenitor cells. Herein, the formation and functionalisation of the 3D-microenviroment is important to determine the survival and fate of the embedded cells. Here we used PuraMatrix (RADA16, PM), a peptide based hydrogel scaffold, which is well described and used to study the influence of a 3D-environment on different cell types. PuraMatrix can be customised easily and the synthetic fabrication of the nano-fibers provides a 3D-culture system of high reliability, which is in addition xeno-free. Recently we have studied the influence of the PM-concentration on the formation of the scaffold. In this study the used concentrations of PM had a direct impact on the formation of the 3D-structure, which was demonstrated by atomic force microscopy. A subsequent analysis of the survival and differentiation of the hNPCs revealed an influence of the used concentrations of PM on the fate of the embedded cells. However, the analysis of survival or neuronal differentiation by means of immunofluorescence techniques posses some hurdles. To gain reliable data, one has to determine the total number of cells within a matrix to obtain the relative number of e.g. neuronal cells marked by βIII-tubulin. This prerequisites a technique to analyse the scaffolds in all 3-dimensions by a confocal microscope or a comparable

  15. The Preoperative Evaluation of Infective Endocarditis via 3-Dimensional Transesophageal Echocardiography.

    Yong, Matthew S; Saxena, Pankaj; Killu, Ammar M; Coffey, Sean; Burkhart, Harold M; Wan, Siu-Hin; Malouf, Joseph F


    Transesophageal echocardiography continues to have a central role in the diagnosis of infective endocarditis and its sequelae. Recent technological advances offer the option of 3-dimensional imaging in the evaluation of patients with infective endocarditis. We present an illustrative case and review the literature regarding the potential advantages and limitations of 3-dimensional transesophageal echocardiography in the diagnosis of complicated infective endocarditis. A 51-year-old man, an intravenous drug user who had undergone bioprosthetic aortic valve replacement 5 months earlier, presented with prosthetic valve endocarditis. Preoperative transesophageal echocardiography with 3D rendition revealed a large abscess involving the mitral aortic intervalvular fibrosa, together with a mycotic aneurysm that had ruptured into the left atrium, resulting in a left ventricle-to-left atrium fistula. Three-dimensional transesophageal echocardiography enabled superior preoperative anatomic delineation and surgical planning. We conclude that 3-dimensional transesophageal echocardiography can be a useful adjunct to traditional 2-dimensional transesophageal echocardiography as a tool in the diagnosis of infective endocarditis.

  16. 3-dimensional resin casting and imaging of mouse portal vein or intrahepatic bile duct system.

    Walter, Teagan J; Sparks, Erin E; Huppert, Stacey S


    In organs, the correct architecture of vascular and ductal structures is indispensable for proper physiological function, and the formation and maintenance of these structures is a highly regulated process. The analysis of these complex, 3-dimensional structures has greatly depended on either 2-dimensional examination in section or on dye injection studies. These techniques, however, are not able to provide a complete and quantifiable representation of the ductal or vascular structures they are intended to elucidate. Alternatively, the nature of 3-dimensional plastic resin casts generates a permanent snapshot of the system and is a novel and widely useful technique for visualizing and quantifying 3-dimensional structures and networks. A crucial advantage of the resin casting system is the ability to determine the intact and connected, or communicating, structure of a blood vessel or duct. The structure of vascular and ductal networks are crucial for organ function, and this technique has the potential to aid study of vascular and ductal networks in several ways. Resin casting may be used to analyze normal morphology and functional architecture of a luminal structure, identify developmental morphogenetic changes, and uncover morphological differences in tissue architecture between normal and disease states. Previous work has utilized resin casting to study, for example, architectural and functional defects within the mouse intrahepatic bile duct system that were not reflected in 2-dimensional analysis of the structure(1,2), alterations in brain vasculature of a Alzheimer's disease mouse model(3), portal vein abnormalities in portal hypertensive and cirrhotic mice(4), developmental steps in rat lymphatic maturation between immature and adult lungs(5), immediate microvascular changes in the rat liver, pancreas, and kidney in response in to chemical injury(6). Here we present a method of generating a 3-dimensional resin cast of a mouse vascular or ductal network


    V. Ravino


    Full Text Available   The paper presents a methodology that permits to construct regression dependences for traction curves of various tractors while using different operational backgrounds. The dependence construction process is carried out with the help of Microsoft Excel.

  18. Treatment of 150 Cases of Lumber Intervertebral Disk Displacement by Acupuncture plus Traction

    CHEN Qing-bao; WU Xue-fei


    Needling Point Jiaji ( Ex-B 2), Dachangshu ( BL 25), Huantiao ( GB 30), Weizhong ( BL 40), and Yanglingquan (GB 34) etc with the cooperation of traction, treated lumbar intervertebral disk displacement.The effective rate was 91.3%.

  19. Iliotibial band traction syndrome in guided motion TKA. A new clinical entity after TKA.

    Luyckx, Lucas; Luyckx, Thomas; Bellemans, Johan; Victor, Jan


    This study aimed at systematic documentation of lateral knee pain in a consecutive series of 1102 cruciate-substituting, guided motion total knee arthroplasties (TKA) (Journey, Smith and Nephew, Memphis, TN, USA) performed in 1085 patients; 1070 knees were available for review. Follow-up time ranged from one to five years, with a mean of 2.5 years. Symptoms mimicking the well known iliotibial band (ITB) friction syndrome were observed in 77 knees (7.2%). Initial conservative treatment consisted of anti-inflammatory medication (77 knees) and local steroid injection (35 knees). The pain persisted in 22 knees (2%), leading to a surgical release of the iliotibial band. Other surgical interventions included revision for infection (6 knees, 0.5%), revision for tibial component loosening (6 knees, 0.5%), revision for tibiofemoral dislocation (3 knees, 0.3%), revision for patellar component loosening (5 knees, 0.4%), revision for instability (1 knee, 0.1%) and secondary patellar resurfacing (1 knee, 0.1%). The overall survivorship with partial or total implant revision as an endpoint was 98%. The development of lateral knee pain in association with the use of a guided motion design can be explained by the forced posterior translation of the lateral condyle in flexion. The asymmetric cam and post mechanism, acting as a hard driver of posterior femoral translation and internal tibial rotation during flexion, does not allow for the natural kinematic variability occurring in native knees. This repetitive and forced stretching of the ITB seems to induce a painful traction syndrome in some patients.

  20. Transcondylar traction as a closed reduction technique in vertically unstable pelvic ring disruption

    Thaunat, M.; Laude, F.; Paillard, P.; Saillant, G.; Catonné, Y.


    Little information is provided in the literature describing an efficient reduction technique for pelvic ring disruption. The aim of this study is to assess the use of the transcondylar traction as a closed reduction technique for vertically unstable fracture-dislocations of the sacro-iliac joint. Twenty-four pelvic ring disruptions were treated with attempted closed reduction followed by percutaneous screw fixation. Transcondylar traction was used as a closed reduction technique. Closed reduc...

  1. Size and composition of airborne particles from pavement wear, tires, and traction sanding.

    Kupiainen, Kaarle J; Tervahattu, Heikki; Räisänen, Mika; Mäkelä, Timo; Aurela, Minna; Hillamo, Risto


    Mineral matter is an important component of airborne particles in urban areas. In northern cities of the world, mineral matter dominates PM10 during spring because of enhanced road abrasion caused by the use of antiskid methods, including studded tires and traction sanding. In this study, factors that affect formation of abrasion components of springtime road dust were assessed. Effects of traction sanding and tires on concentrations, mass size distribution, and composition of the particles were studied in a test facility. Lowest particle concentrations were observed in tests without traction sanding. The concentrations increased when traction sand was introduced and continued to increase as a function of the amount of aggregate dispersed. Emissions were additionally affected by type of tire, properties of traction sand aggregate, and driving speed. Aggregates with high fragmentation resistance and coarse grain size distribution had the lowest emissions. Over 90% of PM10 was mineral particles. Mineralogy of the dust and source apportionment showed that they originated from both traction sand and pavement aggregates. The remaining portion was mostly carbonaceous and originated from tires and road bitumen. Mass size distributions were dominated by coarse particles. Contribution of fine and submicron size ranges were approximately 15 and 10% in PM10, respectively.

  2. Simplified and advanced modelling of traction control systems of heavy-haul locomotives

    Spiryagin, Maksym; Wolfs, Peter; Szanto, Frank; Cole, Colin


    Improving tractive effort is a very complex task in locomotive design. It requires the development of not only mechanical systems but also power systems, traction machines and traction algorithms. At the initial design stage, traction algorithms can be verified by means of a simulation approach. A simple single wheelset simulation approach is not sufficient because all locomotive dynamics are not fully taken into consideration. Given that many traction control strategies exist, the best solution is to use more advanced approaches for such studies. This paper describes the modelling of a locomotive with a bogie traction control strategy based on a co-simulation approach in order to deliver more accurate results. The simplified and advanced modelling approaches of a locomotive electric power system are compared in this paper in order to answer a fundamental question. What level of modelling complexity is necessary for the investigation of the dynamic behaviours of a heavy-haul locomotive running under traction? The simulation results obtained provide some recommendations on simulation processes and the further implementation of advanced and simplified modelling approaches.

  3. A Study of Torque Vectoring and Traction Control for an All-Wheel Drive Electric Vehicle

    Maharun Mui’nuddin


    Full Text Available Common vehicle always experience energy loss during cornering manoeuver. Thus, to ensure it did not happened especially at high speed, a study of torque vectoring and traction control need to be made since it can increase the traction control of tyres during cornering at high speed. The study of torque vectoring and traction control for an all-wheel drive electric vehicle was conducted by modelling an all-wheel drive electric vehicle (EV in ADAMS/Car software. In addition, an optimal control algorithm will be developed for best performance to minimize energy losses using MATLAB/Simulink software. Furthermore, to prove the effectiveness of the all-wheel drive electric, the torque and traction control simulation of the all-wheel drive electric vehicle will be compared with uncontrolled electric vehicle model. According to the result, torque vectoring and traction control of in-wheel motor in all wheel drive EV can help to increase the performance of the electric vehicle during cornering manoeuver. In conclusion, this study of torque vectoring and traction control for an all-wheel drive electric vehicle will help researchers to improve the design of the future electric vehicle in term of the vehicle performance during cornering manoeuvre.

  4. Influence of basketball shoe mass, outsole traction, and forefoot bending stiffness on three athletic movements.

    Worobets, Jay; Wannop, John William


    Prior research has shown that footwear can enhance athletic performance. However, public information is not available on what basketball shoe properties should be selected to maximise movement performance. Therefore, the purpose of the study was to investigate the influence of basketball shoe mass, outsole traction, and forefoot bending stiffness on sprinting, jumping, and cutting performance. Each of these three basketball shoe properties was systematically varied by ± 20% to produce three shoe conditions of varying mass, three conditions of varying traction, and three conditions of varying bending stiffness. Each shoe was tested by 20 recreational basketball players completing maximal effort sprints, vertical jumps, and a cutting drill. Outsole traction had the largest influence on performance, as the participants performed significantly worse in all tests when traction was decreased by 20% (p < 0.001), and performed significantly better in the cutting drill when traction was increased by 20% (p = 0.005). Forefoot bending stiffness had a moderate effect on sprint and cutting performance (p = 0.013 and p = 0.016 respectively) and shoe mass was found to have no effect on performance. Therefore, choosing a shoe with relatively high outsole traction and forefoot bending stiffness should be prioritised, and less concern should be focused on selecting the lightest shoe.

  5. Effects of Non-Uniform Wall Heating on Thermal and Momentum Fields in a 3-Dimensional Urban Environment

    Nazarian, N.; Kleissl, J. P.


    As urbanization progresses, microclimate modifications are also aggravated and the increasing environmental concerns call for more sophisticated methods of urban microclimate analysis. Comprehensive numerical simulations for a clear summer day in southern California are performed in a compact low-rise urban environment. The effect of realistic unsteady, non-uniform thermal forcing, that is caused by solar insolation and inter-building shadowing on thermal and flow conditions are analyzed based on Algebraic Wall-Modeled Large Eddy Simulation (LES) model. The urban thermal field is influenced by urban density, material properties and local weather conditions, as well as urban canyon flow. Urban canyon conditions are translated into vertical and horizontal bulk Richardson numbers indicating atmospheric instability and solar tilt with respect to the momentum forcing of the canyon vortex, respectively. The effect of roof heating is found to be critical on the vortex formation between buildings when the vertical bulk Richardson number is low. Variations of Convective Heat Transfer Coefficients (CHTCs) along building walls are studied and the street canyon ventilation performance is characterized by the mean of air exchange rate (ACH). It is found that volumetric air exchange from street canyons, as well as the distribution of heat transfer along the wall depends strongly on the three-dimensional orientation of the heated wall in relation to wind direction. For example, air removal increases by surface heating and is larger when the leeward wall is heated. In summary, we demonstrate the importance of considering complex realistic conditions on 3-dimensional thermal and momentum fields in Urban Environments.

  6. [Mesenteric traction syndrome during coronary artery bypass graft surgery].

    Koyama, K; Kaneko, I; Mori, K


    Mesenteric traction syndrome (MTS) consists of decreased systemic vascular resistance, increased cardiac output, facial flushing and palmar erythema. Local production of PGI2 is thought to be the cause. We experienced a rare case of MTS that occurred during coronary artery bypass graft surgery (CABG). A 64-year-old man was scheduled for CABG for the treatment of angina pectoris. Hemodynamic variables were stable until 50 minutes after surgical incision. Blood pressure fell down suddenly from 110/50 to 70/40 mmHg, accompanied by obvious facial flushing and palmar erythema, when the surgeons were preparing the right gastroepiploic artery. Hemodynamic changes and cutaneous hyperemia returned to the baseline level in about 40 minutes. After this episode, the operation was performed uneventfully. The time sequence between the onset of the surgical procedure and the hemodynamic and cutaneous findings strongly suggest the release of PGI2 and MTS. In patients undergoing CABG with the gastroepiploic artery graft, pretreatment with NSAID might avoid sudden circulatory changes of MTS.

  7. Super Low Traction under EHD and Mixed Lubrication Regimes

    Vergne, Philippe


    After the pioneered experimental works on superlubricity by Martin et al. on MoS2 [1], Hirano et al. on tungsten and silicon [2] and the further confirmation by Dienwiebel et al. on graphite [3], many groups around the word investigated the occurrence of near frictionless sliding contacts. This large mobilization of tribologists, material sciences specialists and physicists has lead to emerging solutions involving new materials and coatings, the most promising being carbon based like graphite, diamond, carbon composites or diamond-like-carbons. Some of them are currently used in practical applications. The situation is different especially in EHL: the highest friction coefficients are close to 10% when traction fluids are involved, i.e. fluids that have especially designed to transmit the highest friction, and they vary within 3-6% for the rest of lubricants. The range of variation is consequently very narrow and these typical values are really low compared to those obtained in dry contacts: as a consequence ...

  8. 3-Dimensional quantitative detection of nanoparticle content in biological tissue samples after local cancer treatment

    Rahn, Helene, E-mail: [Institute of Fluid Mechanics, Chair of Magnetofluiddynamics, Technische Universitaet Dresden, Dresden 01069 (Germany); Alexiou, Christoph [ENT-Department, Section for Experimental Oncology and Nanomedicine (Else Kröner-Fresenius-Stiftungsprofessur), University Hospital Erlangen, Waldstraße 1, Erlangen 91054 (Germany); Trahms, Lutz [Physikalisch-Technische Bundesanstalt, Abbestraße 2-12, Berlin 10587 (Germany); Odenbach, Stefan [Institute of Fluid Mechanics, Chair of Magnetofluiddynamics, Technische Universitaet Dresden, Dresden 01069 (Germany)


    X-ray computed tomography is nowadays used for a wide range of applications in medicine, science and technology. X-ray microcomputed tomography (XµCT) follows the same principles used for conventional medical CT scanners, but improves the spatial resolution to a few micrometers. We present an example of an application of X-ray microtomography, a study of 3-dimensional biodistribution, as along with the quantification of nanoparticle content in tumoral tissue after minimally invasive cancer therapy. One of these minimal invasive cancer treatments is magnetic drug targeting, where the magnetic nanoparticles are used as controllable drug carriers. The quantification is based on a calibration of the XµCT-equipment. The developed calibration procedure of the X-ray-µCT-equipment is based on a phantom system which allows the discrimination between the various gray values of the data set. These phantoms consist of a biological tissue substitute and magnetic nanoparticles. The phantoms have been studied with XµCT and have been examined magnetically. The obtained gray values and nanoparticle concentration lead to a calibration curve. This curve can be applied to tomographic data sets. Accordingly, this calibration enables a voxel-wise assignment of gray values in the digital tomographic data set to nanoparticle content. Thus, the calibration procedure enables a 3-dimensional study of nanoparticle distribution as well as concentration. - Highlights: • Local cancer treatments are promising in reducing negative side effects occurring during conventional chemotherapy. • The nanoparticles play an important role in delivering drugs to the designated area during local cancer treatments as magnetic drug targeting. • We study the nanoparticles distribution in tumor tissue after magnetic drug targeting with X-ray computed tomography. • We achieved a 3-dimensional quantification of the nanoparticles content in tumor tissue out of digital tomographic data.

  9. A Study of the Power Loss of Traction Continuously Variable Transmission%牵引式无级变速器功率损耗研究



    For studying the traction continuously variable transmission( CVT), analytical formulas for spin speed, traction force of oil film and spin moment are derived. By means of a real example, the relationships of sliding power loss and spin power loss with the contact pressure, traction force of oil film, input rotation speed and geometry curvature ratio are analyzed. It has been shown that the gross power loss for a certain contact pressure and a certain geometry curvature ratio reaches to a minimal value separately. When the oil film traction force becomes greater, both the relative sliding speed and the sliding power loss become also greater, but the spin power loss keeps constant. When the the input rotation speed gets higher, both the sliding power loss and the spin power loss become greater gradually.%以牵引式无级变速器为研究对象,推导出了自转角速度、由油膜滑动产生的牵引力和由自转产生的力矩等解析式。通过实例,计算和分析了由滑动和自转产生的功率损耗与接触压力、油膜牵引力、输入转速和几何曲率比等因素间的变化规律。存在一个接触压力和一个曲率比会使得总功率损耗分别取得极小值。油膜牵引力的增大,必然产生较大的相对滑动速度,增大了功率损耗,但由自转产生的功率损耗不会发生变化。随着输入转速的增大,由相对滑动和自转所产生的功率损耗均会逐渐增大。

  10. Incorporating a 3-dimensional printer into the management of early-stage cervical cancer.

    Baek, Min-Hyun; Kim, Dae-Yeon; Kim, Namkug; Rhim, Chae Chun; Kim, Jong-Hyeok; Nam, Joo-Hyun


    We used a 3-dimensional (3D) printer to create anatomical replicas of real lesions and tested its application in cervical cancer. Our study patient decided to undergo radical hysterectomy after seeing her 3D model which was then used to plan and simulate this surgery. Using 3D printers to create patient-specific 3D tumor models may aid cervical cancer patients make treatment decisions. This technology will lead to better surgical and oncological outcomes for cervical cancer patients. J. Surg. Oncol. 2016;114:150-152. © 2016 Wiley Periodicals, Inc.

  11. Brief communications: visualization of coronary arteries in rats by 3-dimensional real-time contrast echocardiography.

    Ishikura, Fuminobu; Hirayama, Hideo; Iwata, Akiko; Toshida, Tsutomu; Masuda, Kasumi; Otani, Kentaro; Asanuma, Toshihiko; Beppu, Shintaro


    Angiogenesis is under intense investigation to advance the treatment of various ischemic diseases. Small animals, such as mice and rats, are often used for this purpose. However, evaluating the structure of coronary arteries in small animals in situ is not easy. We succeeded in visualizing the coronary artery in rats on 3-dimensional real-time contrast echocardiography using a high-frequency transducer. These methods will be applied for more convenient assessment in a new study, examining issues such as angiogenesis using rats in situ.

  12. Eikonal slant helices and eikonal Darboux helices in 3-dimensional pseudo-Riemannian manifolds

    Önder, Mehmet; Ziplar, Evren


    In this study, we give definitions and characterizations of eikonal slant helices, eikonal Darboux helices and non-normed eikonal Darboux helices in 3-dimensional pseudo- Riemannian manifold M . We show that every eikonal slant helix is also an eikonal Darboux helix for timelike and spacelike curves. Furthermore, we obtain that if the non-null curve a is a non-normed eikonal Darboux helix, then a is an eikonal slant helix if and only if 2 2 e 3k +e1t = constant, where k and t are curvature an...

  13. Computer modelling of the 3-dimensional structures of the cyanobacterial hepatotoxins microcystin-LR and nodularin.

    Lanaras, T; Cook, C M; Eriksson, J E; Meriluoto, J A; Hotokka, M


    The 3-dimensional structures of two cyanobacterial hepatotoxins microcystin-LR, a cyclic heptapeptide and nodularin, a cyclic pentapeptide, and the novel amino acid ADDA (3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid) were constructed, and optimized using the CHEM-X molecular mechanics program. The peptide rings were planar and of rectangular shape. Optimized ADDA formed a U-shape and a difference in the orientation of ADDA with respect to the peptide ring of the two hepatotoxins was observed.

  14. Generation and Active Absorption of 2- and 3-Dimensional Linear Water Waves in Physical Models

    Christensen, Morten

    Methods for mechanical generation of 2-dimensional (2-D) and 3-dimensional (3-D) linear water waves in physical models are presented. The results of a series of laboratory 3-D wave generation tests are presented and discussed. The tests preformed involve reproduction of wave fields characterised...... by different directional wave spectra. The wave generator displacement signals applied in the tests are generated by means of linear digital filtering of Gaussian white noise in the time domain. An absorbing wave generator for 2-D wave facilities (wave channels) is developed. The absorbing wave generator...

  15. Patterned 3-dimensional metal grid electrodes as alternative electron collectors in dye-sensitized solar cells.

    Chua, Julianto; Mathews, Nripan; Jennings, James R; Yang, Guangwu; Wang, Qing; Mhaisalkar, Subodh G


    We describe the application of 3-dimensional metal grid electrodes (3D-MGEs) as electron collectors in dye-sensitized solar cells (DSCs) as a replacement for fluorinated tin oxide (FTO) electrodes. Requirements, structure, advantages, and limitations of the metal grid electrodes are discussed. Solar conversion efficiencies of 6.2% have been achieved in 3D-MGE based solar cells, comparable to that fabricated on FTO (7.1%). The charge transport properties and collection efficiencies in these novel solar cells have been studied using electrochemical impedance spectroscopy.

  16. Hamiltonian Analysis of 3-Dimensional Connection Dynamics in Bondi-like Coordinates

    Huang, Chao-Guang


    The Hamiltonian analysis for a 3-dimensional $SO(1,1)\\times T_+$-connection dynamics is conducted in a Bondi-like coordinate system.A null coframe with 5 independent variables and 9 connection coefficients are treated as basic configuration variables.All constraints and their consistency conditions, as well as the equations of motion,for the system are presented.There is no physical degree of freedom in the system as expected.The Ba\\~nados-Teitelboim-Zanelli spacetime as an example is used to check the analysis.

  17. Towards a mathematical definition of Coulomb branches of $3$-dimensional $\\mathcal N=4$ gauge theories, II

    Braverman, Alexander; Nakajima, Hiraku


    Consider the $3$-dimensional $\\mathcal N=4$ supersymmetric gauge theory associated with a compact Lie group $G_c$ and its quaternionic representation $\\mathbf M$. Physicists study its Coulomb branch, which is a noncompact hyper-K\\"ahler manifold with an $\\mathrm{SU}(2)$-action, possibly with singularities. We give a mathematical definition of the Coulomb branch as an affine algebraic variety with $\\mathbb C^\\times$-action when $\\mathbf M$ is of a form $\\mathbf N\\oplus\\mathbf N^*$, as the second step of the proposal given in arXiv:1503.03676.

  18. Nano-yttria dispersed stainless steel composites composed by the 3 dimensional fiber deposition technique

    Verhiest, K., E-mail: [ArcelorMittal Gent, Hot Strip Mill Department, J. Kennedylaan 51, 9042 Ghent (Belgium); Belgian Nuclear Research Centre, SCK-CEN, Boeretang 200, 2400 Mol (Belgium); Ghent University, UGent, Department of Materials Science and Engineering (DMSE), Technologiepark 903, 9052 Ghent (Belgium); Mullens, S. [Flemish Institute for Technological Research, VITO, Materials Technology, Boeretang 200, 2400 Mol (Belgium); De Wispelaere, N.; Claessens, S. [ArcelorMittal Research Industry Gent, OCAS, J. Kennedylaan 3, 9060 Zelzate (Belgium); DeBremaecker, A. [Belgian Nuclear Research Centre, SCK-CEN, Boeretang 200, 2400 Mol (Belgium); Verbeken, K. [Ghent University, UGent, Department of Materials Science and Engineering (DMSE), Technologiepark 903, 9052 Ghent (Belgium)


    In this study, oxide dispersion strengthened (ODS) 316L steel samples were manufactured by the 3 dimensional fiber deposition (3DFD) technique. The performance of 3DFD as colloidal consolidation technique to obtain porous green bodies based on yttria (Y{sub 2}O{sub 3}) nano-slurries or paste, is discussed within this experimental work. The influence of the sintering temperature and time on sample densification and grain growth was investigated in this study. Hot consolidation was performed to obtain final product quality in terms of residual porosity reduction and final dispersion homogeneity.

  19. A 3-dimensional finite-difference method for calculating the dynamic coefficients of seals

    Dietzen, F. J.; Nordmann, R.


    A method to calculate the dynamic coefficients of seals with arbitrary geometry is presented. The Navier-Stokes equations are used in conjunction with the k-e turbulence model to describe the turbulent flow. These equations are solved by a full 3-dimensional finite-difference procedure instead of the normally used perturbation analysis. The time dependence of the equations is introduced by working with a coordinate system rotating with the precession frequency of the shaft. The results of this theory are compared with coefficients calculated by a perturbation analysis and with experimental results.

  20. A novel solar cell fabricated with spiral photo-electrode for capturing sunlight 3-dimensionally

    LIU Yong; SHEN Hui; DENG Youjun


    A novel solar cell fabricated with spiral photo-electrode for capturing sunlight 3-dimensionally (3D-cell) is proposed in this paper. We studied its performance both in solar simulator and in nature sunlight. Spiral photo-electrode of 3D-cell can receive sunlight from all directions and therefore can track the sun passively. And it is much insensitive to solar azimuth angle and shade. In addition, it increases the area to obtain scattered sunlight and reflected light. Compared with the dye-sensitized solar cells using sandwich structure, it would be more advantageous in the sealing technique.

  1. Quantum Computing - A new Implementation of Simon Algorithm for 3-Dimensional Registers

    Adina Bărîlă


    Full Text Available Quantum computing is a new field of science aiming to use quantum phenomena in order to perform operations on data. The Simon algorithm is one of the quantum algorithms which solves a certain problem exponentially faster than any classical algorithm solving the same problem. Simulating of quantum algorithms is very important since quantum hardware is not available outside of the research labs. QCL (Quantum Computation Language is the most advanced implemented quantum computer simulator and was conceived by Bernhard Ömer. The paper presents an implementation in QCL of the Simon algorithm in the case of 3-dimensional registers.

  2. Design of the Buffer Structure of Traction Running with a Constant Speed%恒定速度牵引运行的缓冲结构设计

    罗茜; 曾宪任


    This paper mainly aimed to study buffer structure design on the traction transport system when the traction transport boundary conditions were given.With such conditions as the maximum impact force,traction speed,maximum speed of alluvium,the elasticity coefficient and the mass of buffer structure,a mathematical model was established and the solution of differential equations was solved.At last,a program was compiled with MATLAB language.With this program the elasticity coefficient and the maximum impact force which meet the requirements in impact process could be solved as long as the boundary conditions were input.This provided a quick design basis of buffer structure for most mechanical engineers.%主要研究牵引运输中的缓冲结构设计;通过对给定的牵引运输的边界条件:最大冲击作用力、牵引速度、冲击物最大速度、缓冲结构弹性系数及质量,建立数学模型,求解微分方程,得到问题的解;最后通过MATLAB语言对问题的求解过程进行了程序设计,只要将边界条件输入,就可以解出满足要求的缓冲结构的弹性系数及冲击过程的最大冲击力。给广大机械设计人员提供了快速的缓冲结构设计依据。

  3. Unobservable Problem of Target Tracking with Bearing-only Measurements in 3-dimensional Space

    XU Zhi-gang; SHENG An-dong


    The bearings-only tracking (BOT) system is said to be observability if and only if the target motion parameters can be uniquely determined by noise-free bearing measurements. By utilizing the method of orthogonal vectors and characteristic of linear matrix equation, the problem of observability for BOT in noise-free bearings measurements from single observer is discussed based on the target and observer traveling in the 3-dimensional space. A proposition that BOT for target and observer traveling in the 3-dimensional space with constant acceleration remains unsolvable is presented and proved. By proving the proposition, it is also shown that some motion parameter ratios of target can be estimated under certain condition satisfied by measurements and time samples. The proposition is extended to arbitrary rank of manoeuvre for the observer and the target, which BOT remains unobservable property while the rank of target manoeuvre is higher than that of the observer manoeuvre. The theoretical analysis of this paper provides the guidelines for how the observer trajectory should be formulated to avoid unobservable state for BOT in practice application.

  4. 3-dimensional slope stability analyses using non-associative stress-strain relationships


    The research work presented in this paper refers to a new slope stability analysis method used for landslide risk evaluations. It is an extension of the 3-dimensional upper-bound slope stability analysis method proposed by Chen et al. in 2001,which employs the Mohr-Coulomb’s associative flow rule. It has been found that in a 3-dimensional area,a prism may not be able to move at friction angles to all its surrounding interfaces,as required by this associative rule,and convergence problems may occasionally arise. The new method establishes two velocity fields:(i) The plastic one that represents a non-associative and the best representative dilation behavior,and (ii) the virtual one that permits the solution for factor of safety in the work and energy balance equation. The new method can then allow any input value of dilation angle and thus solve the convergence problem. A practical application to a concrete dam foundation is illustrated.

  5. Candidate gene analyses of 3-dimensional dentoalveolar phenotypes in subjects with malocclusion

    Weaver, Cole A.; Miller, Steven F.; da Fontoura, Clarissa S. G.; Wehby, George L.; Amendt, Brad A.; Holton, Nathan E.; Allareddy, Veeratrishul; Southard, Thomas E.; Moreno Uribe, Lina M.


    Introduction Genetic studies of malocclusion etiology have identified 4 deleterious mutations in genes, DUSP6, ARHGAP21, FGF23, and ADAMTS1 in familial Class III cases. Although these variants may have large impacts on Class III phenotypic expression, their low frequency (subjects were digitized with 48 landmarks. The 3-dimensional coordinate data were submitted to a geometric morphometric approach along with principal component analysis to generate continuous phenotypes including symmetric and asymmetric components of dentoalveolar shape variation, fluctuating asymmetry, and size. The subjects were genotyped for 222 single-nucleotide polymorphisms in 82 genes/loci, and phenotpye-genotype associations were tested via multivariate linear regression. Results Principal component analysis of symmetric variation identified 4 components that explained 68% of the total variance and depicted anteroposterior, vertical, and transverse dentoalveolar discrepancies. Suggestive associations (P right discrepancies resulting in midline deviations, unilateral crossbites, and ectopic eruptions. Suggestive associations were found with TBX1 AJUBA, SNAI3 SATB2, TP63, and 1p22.1. Fluctuating asymmetry was associated with BMP3 and LATS1. Associations for SATB2 and BMP3 with asymmetric variations remained significant after the Bonferroni correction (P <0.00022). Suggestive associations were found for centroid size, a proxy for dentoalveolar size variation with 4p16.1 and SNAI1. Conclusions Specific genetic pathways associated with 3-dimensional dentoalveolar phenotypic variation in malocclusions were identified. PMID:28257739

  6. Simple parameter estimation for complex models — Testing evolutionary techniques on 3-dimensional biogeochemical ocean models

    Mattern, Jann Paul; Edwards, Christopher A.


    Parameter estimation is an important part of numerical modeling and often required when a coupled physical-biogeochemical ocean model is first deployed. However, 3-dimensional ocean model simulations are computationally expensive and models typically contain upwards of 10 parameters suitable for estimation. Hence, manual parameter tuning can be lengthy and cumbersome. Here, we present four easy to implement and flexible parameter estimation techniques and apply them to two 3-dimensional biogeochemical models of different complexities. Based on a Monte Carlo experiment, we first develop a cost function measuring the model-observation misfit based on multiple data types. The parameter estimation techniques are then applied and yield a substantial cost reduction over ∼ 100 simulations. Based on the outcome of multiple replicate experiments, they perform on average better than random, uninformed parameter search but performance declines when more than 40 parameters are estimated together. Our results emphasize the complex cost function structure for biogeochemical parameters and highlight dependencies between different parameters as well as different cost function formulations.

  7. MR imaging of the knee joint with 3-dimensional gradient echo

    Shimagaki, Hajime; Matsubara, T.; Narisawa, Hiroko; Yamazaki, Yukio [Tsubame Rosai Hospital, Niigata (Japan)


    Authors considered and discussed whether various lesions of the knee joint can be diagnosed under the MR imaging condition with a pulse sequence of 3-dimensional fourier transformed gradient recalled acquisition in the steady state and what advantages the method has. The apparatus was 1.5T Signa (General Electric) equipped with surface coil for the knee. The consecutive 124 sagittal images of 0.8 mm thickness taken primarily for 3-dimensional reconstruction were processed to give any cross sections of coronary, horizontal, sagittal or further additional ones. Subjects were 243 knees (138 internal derangement and 105 osteoarthritis) whose lesions were confirmed by arthroscope or by arthrostomy after the MR imaging. Comparison of the MR imaging and surgical finding revealed that accuracy, specificity and sensitivity of the present MR imaging method were all >90% for diagnosis of internal derangement of anterior cruciate ligament and meniscus. For osteoarthritis, the method was thought useful for evaluation of the depth of cartilage deficit. (K.H.)

  8. Comparison of nonnavigated and 3-dimensional image-based computer navigated balloon kyphoplasty.

    Sembrano, Jonathan N; Yson, Sharon C; Polly, David W; Ledonio, Charles Gerald T; Nuckley, David J; Santos, Edward R G


    Balloon kyphoplasty is a common treatment for osteoporotic and pathologic compression fractures. Advantages include minimal tissue disruption, quick recovery, pain relief, and in some cases prevention of progressive sagittal deformity. The benefit of image-based navigation in kyphoplasty has not been established. The goal of this study was to determine whether there is a difference between fluoroscopy-guided balloon kyphoplasty and 3-dimensional image-based navigation in terms of needle malposition rate, cement leakage rate, and radiation exposure time. The authors compared navigated and nonnavigated needle placement in 30 balloon kyphoplasty procedures (47 levels). Intraoperative 3-dimensional image-based navigation was used for needle placement in 21 cases (36 levels); conventional 2-dimensional fluoroscopy was used in the other 9 cases (11 levels). The 2 groups were compared for rates of needle malposition and cement leakage as well as radiation exposure time. Three of 11 (27%) nonnavigated cases were complicated by a malpositioned needle, and 2 of these had to be repositioned. The navigated group had a significantly lower malposition rate (1 of 36; 3%; P=.04). The overall rate of cement leakage was also similar in both groups (P=.29). Radiation exposure time was similar in both groups (navigated, 98 s/level; nonnavigated, 125 s/level; P=.10). Navigated kyphoplasty procedures did not differ significantly from nonnavigated procedures except in terms of needle malposition rate, where navigation may have decreased the need for needle repositioning.

  9. Crossover from 2-dimensional to 3-dimensional aggregations of clusters on square lattice substrates

    Cheng, Yi; Zhu, Yu-Hong; Pan, Qi-Fa; Yang, Bo; Tao, Xiang-Ming; Ye, Gao-Xiang


    A Monte Carlo study on the crossover from 2-dimensional to 3-dimensional aggregations of clusters is presented. Based on the traditional cluster-cluster aggregation (CCA) simulation, a modified growth model is proposed. The clusters (including single particles and their aggregates) diffuse with diffusion step length l (1 ≤ l ≤ 7) and aggregate on a square lattice substrate. If the number of particles contained in a cluster is larger than a critical size sc, the particles at the edge of the cluster have a possibility to jump onto the upper layer, which results in the crossover from 2-dimensional to 3-dimensional aggregations. Our simulation results are in good agreement with the experimental findings. Project supported by the National Natural Science Foundation of China (Grant Nos. 11374082 and 11074215), the Science Foundation of Zhejiang Province Department of Education, China (Grant No. Y201018280), the Fundamental Research Funds for Central Universities, China (Grant No. 2012QNA3010), and the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20100101110005).

  10. Device for lengthening of a musculotendinous unit by direct continuous traction in the sheep

    Zumstein Matthias A


    Full Text Available Abstract Background Retraction, atrophy and fatty infiltration are signs subsequent to chronic rotator cuff tendon tears. They are associated with an increased pennation angle and a shortening of the muscle fibers in series. These deleterious changes of the muscular architecture are not reversible with current repair techniques and are the main factors for failed rotator cuff tendon repair. Whereas fast stretching of the retracted musculotendinous unit results in proliferation of non-contractile fibrous tissue, slow stretching may lead to muscle regeneration in terms of sarcomerogenesis. To slowly stretch the retracted musculotendinous unit in a sheep model, two here described tensioning devices have been developed and mounted on the scapular spine of the sheep using an expandable threaded rod, which has been interposed between the retracted tendon end and the original insertion site at the humeral head. Traction is transmitted in line with the musculotendinous unit by sutures knotted on the expandable threaded rod. The threaded rod of the tensioner is driven within the body through a rotating axis, which enters the body on the opposite side. The tendon end, which was previously released (16 weeks prior from its insertion site with a bone chip, was elongated with a velocity of 1 mm/day. Results After several steps of technical improvements, the tensioner proved to be capable of actively stretching the retracted and degenerated muscle back to the original length and to withstand the external forces acting on it. Conclusion This technical report describes the experimental technique for continuous elongation of the musculotendinous unit and reversion of the length of chronically shortened muscle.



    This article is concerned with second-order necessary and sufficient optimality conditions for optimal control problems governed by 3-dimensional Navier-Stokes equations. The periodic state constraint is considered.

  12. The value of preoperative 3-dimensional over 2-dimensional valve analysis in predicting recurrent ischemic mitral regurgitation after mitral annuloplasty

    Wijdh-den Hamer, Inez J.; Bouma, Wobbe; Lai, Eric K.; Levack, Melissa M.; Shang, Eric K.; Pouch, Alison M.; Eperjesi, Thomas J.; Plappert, Theodore J.; Yushkevich, Paul A.; Hung, Judy; Mariani, Massimo A.; Khabbaz, Kamal R.; Gleason, Thomas G.; Mahmood, Feroze; Acker, Michael A.; Woo, Y. Joseph; Cheung, Albert T.; Gillespie, Matthew J.; Jackson, Benjamin M.; Gorman, Joseph H.; Gorman, Robert C.


    Objectives: Repair for ischemic mitral regurgitation with undersized annuloplasty is characterized by high recurrence rates. We sought to determine the value of pre-repair 3-dimensional echocardiography over 2-dimensional echocardiography in predicting recurrence at 6 months. Methods: Intraoperative

  13. Nano-mechanics of Tunable Adhesion using Non Covalent Forces

    Kenneth Liechti


    The objective of this program was to examine, via experiment and atomistic and continuum analysis, coordinated noncovalent bonding over a range of length scales with a view to obtaining modulated, patterned and reversible bonding at the molecular level. The first step in this project was to develop processes for depositing self-assembled monolayers (SAMs) bearing carboxylic acid and amine moieties on Si (111) surfaces and probe tips of an interfacial force microscope (IFM). This allowed the adhesive portion of the interactions between functionalized surfaces to be fully captured in the force-displacement response (force profiles) that are measured by the IFM. The interactionswere extracted in the form of traction-separation laws using combined molecular and continuum stress analyses. In this approach, the results of molecular dynamics analyses of SAMs subjected to simple stress states are used to inform continuum models of their stress-strain behavior. Continuum analyses of the IFM experiment were then conducted, which incorporate the stress-strain behavior of the SAMs and traction-separation relations that represent the interactions between the tip and functionalized Si surface. Agreement between predicted and measured force profiles was taken to imply that the traction-separation relations have been properly extracted. Scale up to larger contact areas was considered by forming Si/SAM/Si sandwiches and then separating them via fracture experiments. The mode 1 traction-separation relations have been extracted using fracture mechanics concepts under mode 1 and mixed-mode conditions. Interesting differences were noted between the three sets of traction-separation relations.

  14. Oracle9i database gains traction among leading European customers


    The Oracle Corporation software group, today announced that more than 600 customers worldwide have purchased Oracle9i Real Application Clusters. Some of the European customers include Austrian Railways, BACS, Bavarian Police Force, CERN, e-Spatial, Navision a/s and the North Rhine-Westphalia Police Force.


    I.V. Domanskyi


    Full Text Available Currently, the cause deterioration of quality rating of electricity on tire traction substations AC can be either how mode of operation of power systems, industrial loads so and the impact of electric traction. The experience of energy surveys show that the loss from flow potential equalization currents in each the third plot between traction substations AC is amount to not less than 250 thousand kW∙h per year. To select the optimum power and places location of the device longitudinal capacitive of compensation and decision other tasks it is necessary methodology of systems of calculation that takes into account the complex nature of the mutual influence of the quality of the electricity coming from the energy system of and the transportation process. In the paper proposed three options for calculation algorithms modes work of existing and perspective systems, traction power supply AC jointly with power supply their by energy systems, including the algorithm for calculating networks of different nominal voltages using the transformations; decomposition and synthesis of networks with different voltage levels; the iterations and probabilistic assessment of the impact of power mains. Developed the schemes formalization of graphs and the matrices of portions of the outer and traction power supply and method of selecting parameters and places location of the devices longitudinal capacitive of compensation, which are based on direct methods solving systems of linear algebraic equations with a dense banded and profile-sparse the matrix. Are generalized ways of formation and transformation of graphs of schemes traction power supply and feeding them energy systems and proposed the method of calculation the complex the moment of schemes, which increases the accuracy of calculating of flows power on traction networks to 1-2 % and allows you to select the optimal parameters and places location of the devices longitudinal capacitive of compensation

  16. Numerical estimation of 3D mechanical forces exerted by cells on non-linear materials.

    Palacio, J; Jorge-Peñas, A; Muñoz-Barrutia, A; Ortiz-de-Solorzano, C; de Juan-Pardo, E; García-Aznar, J M


    The exchange of physical forces in both cell-cell and cell-matrix interactions play a significant role in a variety of physiological and pathological processes, such as cell migration, cancer metastasis, inflammation and wound healing. Therefore, great interest exists in accurately quantifying the forces that cells exert on their substrate during migration. Traction Force Microscopy (TFM) is the most widely used method for measuring cell traction forces. Several mathematical techniques have been developed to estimate forces from TFM experiments. However, certain simplifications are commonly assumed, such as linear elasticity of the materials and/or free geometries, which in some cases may lead to inaccurate results. Here, cellular forces are numerically estimated by solving a minimization problem that combines multiple non-linear FEM solutions. Our simulations, free from constraints on the geometrical and the mechanical conditions, show that forces are predicted with higher accuracy than when using the standard approaches.


    Mamoona Anwar


    Full Text Available Background: Cervical radiculopathy is a condition of pain and sensorimotor deficits due to cervical nerve root compression. The symptoms may include weakness, tingling, numbness and pain. C6, C7 nerve roots are most involved in cervical radiculopathy. Various modalities and therapeutic interventions are used and recommended for management of cervical radiculopathy including cervical collars, immobilization, manipulation, cervical traction TENS and therapeutic exercises.The aimof this study is to evaluate the efficacy of neurodynamics in comparison to manual traction in the management of cervical radiculopathy. Methods: An Interventional research was performed in the Department of Physiotherapy, Mayo hospital Lahore, Pakistan. 40 subjects aged between 18-60 years participated in the study. They were divided into two groups namely Group A and Group B with 20 subjects in each group. The duration of the study was 4 weeks with 4 sessions per week. GroupA received neurodynamics along with strengthening exercises while Group B received manual traction along with strengthening exercises. Neck Disability Index (NDI scale was used as an outcome measure andpaired sample t-test was used for statistical analysis. Results: A significant improvement was found in both neurodynamics group and manual traction group for pain and functional status with p value< 0.05. Conclusion: This study concluded that the treatment techniques, neurodynamics and manual traction were effective in alleviating the symptoms associated with cervical radiculopathy in terms of decreasing pain intensity, increasing ranges of motion and improving functional capacity.

  18. DIEP Flap Breast Reconstruction Using 3-dimensional Surface Imaging and a Printed Mold

    Koichi Tomita, MD, PhD


    Full Text Available Summary: Recent advances in 3-dimensional (3D surface imaging technologies allow for digital quantification of complex breast tissue. We performed 11 unilateral breast reconstructions with deep inferior epigastric artery perforator (DIEP flaps (5 immediate, 6 delayed using 3D surface imaging for easier surgery planning and 3D-printed molds for shaping the breast neoparenchyma. A single- or double-pedicle flap was preoperatively planned according to the estimated tissue volume required and estimated total flap volume. The DIEP flap was then intraoperatively shaped with a 3D-printed mold that was based on a horizontally inverted shape of the contralateral breast. Cosmetic outcomes were assessed as satisfactory, as confirmed by the postoperative 3D measurements of bilateral breasts. We believe that DIEP flap reconstruction assisted with 3D surface imaging and a 3D-printed mold is a simple and quick method for rebuilding a symmetric breast.

  19. Vectors a Fortran 90 module for 3-dimensional vector and dyadic arithmetic

    Brock, B.C.


    A major advance contained in the new Fortran 90 language standard is the ability to define new data types and the operators associated with them. Writing computer code to implement computations with real and complex three-dimensional vectors and dyadics is greatly simplified if the equations can be implemented directly, without the need to code the vector arithmetic explicitly. The Fortran 90 module described here defines new data types for real and complex 3-dimensional vectors and dyadics, along with the common operations needed to work with these objects. Routines to allow convenient initialization and output of the new types are also included. In keeping with the philosophy of data abstraction, the details of the implementation of the data types are maintained private, and the functions and operators are made generic to simplify the combining of real, complex, single- and double-precision vectors and dyadics.

  20. A customizable 3-dimensional digital atlas of the canary brain in multiple modalities

    Vellema, Michiel; Verschueren, Jacob; Van Meir, Vincent


    the number of detectable brain regions, including most of the areas involved in song perception, learning, and production. The brain atlas can readily be used to determine the stereotactic location of delineated brain areas at any desirable head angle. Alternatively the brain data can be used to determine...... throughout their lives. This trait makes this bird species particularly valuable to study the functional relationship between the continued plasticity in the singing behavior and alterations in the anatomy and physiology of the brain. In order to optimally interpret these types of studies, a detailed...... understanding of the brain anatomy is essential. Because traditional 2-dimensional brain atlases are limited in the information they can provide about the anatomy of the brain, here we present a 3-dimensional MRI-based atlas of the canary brain. Using multiple imaging protocols we were able to maximize...

  1. Reference Trajectory Generation for 3-Dimensional Walking of a Humanoid Robot


    Humanoid walking planning is a complicated task because of the high number of degrees of freedom (DOFs) and the variable mechanical structure during walking. In this paper, a planning method for 3-dimensional (3-D) walking movements was developed based on a model of a typical humanoid robot with 12 DOFs on the lower body. The planning process includes trajectory generation for the hip, ankle, and knee joints in the Cartesian space. The balance of the robot was ensured by adjusting the hip motion. The angles for each DOF were obtained from 3-D kinematics calculation. The calculation gave reference trajectories of all the DOFs on the humanoid robot which were used to control the real robot. The simulation results show that the method is effective.

  2. Investigation of 3-dimensional structural morphology for enhancing light trapping with control of surface haze

    Park, Hyeongsik; Shin, Myunghun; Kim, Hyeongseok; Kim, Sunbo; Le, Anh Huy Tuan; Kang, Junyoung; Kim, Yongjun; Pham, Duy Phong; Jung, Junhee; Yi, Junsin


    A comparative study of 3-dimensional textured glass morphologies with variable haze value and chemical texturing of the glass substrates was conducted to enhance light trapping in silicon (Si) thin film solar cells (TFSCs). The light trapping characteristics of periodic honeycomb structures show enhanced transmittance and haze ratio in numerical and experimental approaches. The periodic honeycomb structure of notched textures is better than a random or periodic carved structure. It has high transmittance of ∼95%, and haze ratio of ∼52.8%, and the haze property of the angular distribution function of transmittance shows wide scattering angles in the long wavelength region because of the wide spacing and aspect ratio of the texture. The numerical and experimental approaches of the 3-D texture structures in this work will be useful in developing high-performance Si TFSCs with light trapping.

  3. Simple computer program to model 3-dimensional underground heat flow with realistic boundary conditions

    Metz, P. D.

    A FORTRAN computer program called GROCS (GRound Coupled Systems) has been developed to study 3-dimensional underground heat flow. Features include the use of up to 30 finite elements or blocks of Earth which interact via finite difference heat flow equations and a subprogram which sets realistic time and depth dependent boundary conditions. No explicit consideration of mositure movement or freezing is given. GROCS has been used to model the thermal behavior of buried solar heat storage tanks (with and without insulation) and serpentine pipe fields for solar heat pump space conditioning systems. The program is available independently or in a form compatible with specially written TRNSYS component TYPE subroutines. The approach taken in the design of GROCS, the mathematics contained and the program architecture, are described. Then, the operation of the stand-alone version is explained. Finally, the validity of GROCS is discussed.

  4. On Exact Controllability of Networks of Nonlinear Elastic Strings in 3-Dimensional Space

    Günter R. LEUGERING; E. J. P. Georg SCHMIDT


    This paper concerns a system of nonlinear wave equations describing the vibrations of a 3-dimensional network of elastic strings.The authors derive the equations and appropriate nodal conditions,determine equilibrium solutions,and,by using the methods of quasilinear hyperbolic systems,prove that for tree networks the natural initial,bound-ary value problem has classical solutions existing in neighborhoods of the "stretched" equilibrium solutions.Then the local controllability of such networks near such equilibrium configurations in a certain specified time interval is proved.Finally,it is proved that,given two different equilibrium states satisfying certain conditions,it is possible to control the network from states in a small enough neighborhood of one equilibrium to any state in a suitable neighborhood of the second equilibrium over a sufficiently large time interval.

  5. Use of 3-Dimensional Printing for Preoperative Planning in the Treatment of Recurrent Anterior Shoulder Instability

    Sheth, Ujash; Theodoropoulos, John; Abouali, Jihad


    Recurrent anterior shoulder instability often results from large bony Bankart or Hill-Sachs lesions. Preoperative imaging is essential in guiding our surgical management of patients with these conditions. However, we are often limited to making an attempt to interpret a 3-dimensional (3D) structure using conventional 2-dimensional imaging. In cases in which complex anatomy or bony defects are encountered, this type of imaging is often inadequate. We used 3D printing to produce a solid 3D model of a glenohumeral joint from a young patient with recurrent anterior shoulder instability and complex Bankart and Hill-Sachs lesions. The 3D model from our patient was used in the preoperative planning stages of an arthroscopic Bankart repair and remplissage to determine the depth of the Hill-Sachs lesion and the degree of abduction and external rotation at which the Hill-Sachs lesion engaged. PMID:26759768

  6. Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes.

    Degner-Leisso, Stephanie C; Feeney, Ann J


    V(D)J recombination is a crucial component of the adaptive immune response, allowing for the production of a diverse antigen receptor repertoire (Ig and TCR). This review will focus on how epigenetic regulation and 3-dimensional (3D) interactions may control V(D)J recombination at Ig loci. The interplay between transcription factors and post-translational modifications at the Igh, Igκ, and Igλ loci will be highlighted. Furthermore, we propose that the spatial organization and epigenetic boundaries of each Ig loci before and during V(D)J recombination may be influenced in part by the CTCF/cohesin complex. Taken together, the many epigenetic and 3D layers of control ensure that Ig loci are only rearranged at appropriate stages of B cell development.

  7. Towards a mathematical definition of Coulomb branches of $3$-dimensional $\\mathcal N=4$ gauge theories, I

    Nakajima, Hiraku


    Consider the $3$-dimensional $\\mathcal N=4$ supersymmetric gauge theory associated with a compact Lie group $G$ and its quaternionic representation $\\mathbf M$. Physicists study its Coulomb branch, which is a noncompact hyper-K\\"ahler manifold, such as instanton moduli spaces on $\\mathbb R^4$, $SU(2)$-monopole moduli spaces on $\\mathbb R^3$, etc. In this paper and its sequel, we propose a mathematical definition of the coordinate ring of the Coulomb branch, using the vanishing cycle cohomology group of a certain moduli space for a gauged $\\sigma$-model on the $2$-sphere associated with $(G,\\mathbf M)$. In this first part, we check that the cohomology group has the correct graded dimensions expected from the monopole formula proposed by Cremonesi, Hanany and Zaffaroni arXiv:1309.2657. A ring structure (on the cohomology of a modified moduli space) will be introduced in the sequel of this paper.

  8. Large-eddy-simulation of 3-dimensional Rayleigh-Taylor instability in incompressible fluids


    The 3-dimensional incompressible Rayleigh-Taylor instability is numerically studied through the large-eddy-simulation (LES) approach based on the passive scalar transport model. Both the instantaneous velocity and the passive scalar fields excited by sinusoidal perturbation and random perturbation are simulated. A full treatment of the whole evolution process of the instability is addressed. To verify the reliability of the LES code, the averaged turbulent energy as well as the flux of passive scalar are calculated at both the resolved scale and the subgrid scale. Our results show good agreement with the experimental and other numerical work. The LES method has proved to be an effective approach to the Rayleigh-Taylor instability.

  9. The distribution of particles in the plane dispersed by a simple 3-dimensional diffusion process

    Stockmarr, Anders


    Populations of particles dispersed in the 2-dimensional plane from a single pointsource may be grouped as focus expansion patterns, with an exponentially decreasing density, and more diffuse patterns with thicker tails. Exponentially decreasing distributions are often modelled as the result of 2......-dimensional diffusion processes acting to disperse the particles, while thick-tailed distributions tend to be modelled by purely descriptive distributions. Models based on the Cauchy distribution have been suggested, but these have not been related to diffusion modelling. However, the distribution...... of particles dispersed from a point source by a 3-dimensional Brownian motion that incorporates a constant drift, under the condition that the particle starts at a given height and is stopped when it reaches the xy plane (zero height) may be shown to result in both slim-tailed exponentially decreasing...

  10. The role of the cytoskeleton in cellular force generation in 2D and 3D environments

    Kraning-Rush, Casey M.; Carey, Shawn P.; Califano, Joseph P.; Smith, Brooke N.; Reinhart-King, Cynthia A.


    To adhere and migrate, cells generate forces through the cytoskeleton that are transmitted to the surrounding matrix. While cellular force generation has been studied on 2D substrates, less is known about cytoskeletal-mediated traction forces of cells embedded in more in vivo-like 3D matrices. Recent studies have revealed important differences between the cytoskeletal structure, adhesion, and migration of cells in 2D and 3D. Because the cytoskeleton mediates force, we sought to directly compare the role of the cytoskeleton in modulating cell force in 2D and 3D. MDA-MB-231 cells were treated with agents that perturbed actin, microtubules, or myosin, and analyzed for changes in cytoskeletal organization and force generation in both 2D and 3D. To quantify traction stresses in 2D, traction force microscopy was used; in 3D, force was assessed based on single cell-mediated collagen fibril reorganization imaged using confocal reflectance microscopy. Interestingly, even though previous studies have observed differences in cell behaviors like migration in 2D and 3D, our data indicate that forces generated on 2D substrates correlate with forces within 3D matrices. Disruption of actin, myosin or microtubules in either 2D or 3D microenvironments disrupts cell-generated force. These data suggest that despite differences in cytoskeletal organization in 2D and 3D, actin, microtubules and myosin contribute to contractility and matrix reorganization similarly in both microenvironments.

  11. Traction endurance biomechanical study of metallic suture anchors at different insertion angles

    Azato Flávia Namie


    Full Text Available The suture anchors' insertion angle and its traction resistance are the main subjects of this study. Twenty trials were realized using threaded suture anchors in four diferents angulations (30º /45º /60º /90º in human bone (distal femur and another twenty trials in artificial bone (SawboneTM. The anchors were pulled out being tractioned uprightly from its bone surface by a Kratos Universal test machine. The human bone results found no relation between the main subjects of this study, so whithout statistical value. On the other hand at the artificial bone the insertion angle of 90º beared more traction, being statistically significant compared to the other angles.

  12. Bayesian Network Based Fault Prognosis via Bond Graph Modeling of High-Speed Railway Traction Device

    Yunkai Wu


    component-level faults accurately for a high-speed railway traction system, a fault prognosis approach via Bayesian network and bond graph modeling techniques is proposed. The inherent structure of a railway traction system is represented by bond graph model, based on which a multilayer Bayesian network is developed for fault propagation analysis and fault prediction. For complete and incomplete data sets, two different parameter learning algorithms such as Bayesian estimation and expectation maximization (EM algorithm are adopted to determine the conditional probability table of the Bayesian network. The proposed prognosis approach using Pearl’s polytree propagation algorithm for joint probability reasoning can predict the failure probabilities of leaf nodes based on the current status of root nodes. Verification results in a high-speed railway traction simulation system can demonstrate the effectiveness of the proposed approach.

  13. Some effects of grooved runway configurations on aircraft tire braking traction under flooded runway conditions

    Byrdsong, T. A.


    An experimental investigation was conducted to study the effect of grooved runway configurations on aircraft tire braking traction on flooded runway surfaces. The investigation was performed, utilizing size 49 x 17, type VII, aircraft tires with an inflation pressure of 170 lb per square inch at ground speeds up to approximately 120 knots. The results of this investigation indicate that when the runway is flooded, grooved surfaces provide better braking traction than an ungrooved surface and, in general, the level of braking traction was found to improve as the tire bearing pressure was increased because of an increase in the groove area of either the surface or the tire tread. Rounding the groove edges tended to degrade the tire braking capability from that developed on the same groove configuration with sharp edges. Results also indicate that braking friction coefficients for the test tires and runway surfaces decreased as ground speed was increased because of the hydroplaning effects.

  14. Evaluation of Stress Intensity Factors for Multiple Cracked Circular Disks Under Crack Surface Tractions with SBFEM

    LIU Jun-yu; LIN Gao; LI Xiao-chuan; XU Feng-lin


    Stress intensity factors (SIFs) for the cracked circular disks under different distributing surface tractions are evaluated with the scaled boundary finite element method (SBFEM).In the SBFEM,the analytical advantage of the solution in the radial direction allows SIFs to be directly determined from its definition,therefore no special crack-tip treatment is necessary.Furthermore anisotropic material behavior can be treated easily.Different distributions of surface tractions are considered for the center and double-edge-cracked disks.The benchmark examples are modeled and an excellent agreement between the results in the present study and those in published literature is found.It shows that SBFEM is effective and possesses high accuracy.The SIFs of the cracked orthotropic material circular disks subjected to different surface tractions are also evaluated.The technique of substructure is applied to handle the multiple cracks problem.

  15. Zero Dynamics Analysis for Inverse Decoupling Control of Asynchronous Traction Motor

    Haiying Dong


    Full Text Available Considering the problem for inverse system method in EMU AC induction traction motor linear decoupling, the zero dynamics subsystem will be separated from the original dynamic system through coordinate transformation. Firstly, a getting method for zero dynamics of the multiple input multiple output nonlinear system is discussed when γ<n. Second, the zero dynamics analysis for five order nonlinear model of asynchronous traction motor which base on the stationary coordinate system is given by using inverse decoupling method. The analysis results show that if the stability of the zero dynamics can be ensured, then the entire linearization of original nonlinear system is not necessary, need only partial linearization which effect on the external dynamic portion. The inverse decoupling process of asynchronous traction motor can be simplified by this conclusion.

  16. Head-Down Tilt with Balanced Traction as a Model for Simulating Spinal Acclimation to Microgravity

    Ballard, R. E.; Styf, J. R.; Watenpaugh, D. E.; Fechner, K.; Haruna, Y.; Kahan, N. J.; Hargens, A. R.


    Astronauts experience total body height increases of 4 to 7 cm in microgravity. Thus, stretching of the spinal cord, nerve roots, and muscular and ligamentous tissues may be responsible for the hyperreflexia, back pain, and muscular atrophy associated with exposure to microgravity. Axial compression of the spine makes 6 deg. head-down tilt (HDT) an unsuitable model for spinal acclimation to microgravity. However, this axial compression may be counteracted by balanced traction consisting of 10% body weight (sin 6 deg. = 0.1) applied to the legs. Six healthy male subjects underwent 3 days each of 60 HDT with balanced traction and horizontal bed rest (HBR), with a 2 week recovery period between treatments. Total body and spine length, lumbar disc height, back pain, erector spinae intramuscular pressure, and ankle joint torque were measured before, during and after each treatment. Total body and spine (processes of L5 - C7) lengths increased significantly more during HDT with balanced traction (22 +/- 8 mm and 25 +/- 8 mm, respectively) than during HBR (16 +/- 4 mm and 14 +/- 9 mm, respectively). Back and leg pain were significantly greater during HDT with balanced traction than during HBR. The distance between the lower end plate of L4 and the upper endplate of S1, as measured by sonography, increased significantly in both treatments to the same degree (2.9 +/- 1.9 mm, HDT with balanced traction; 3.3 +/- 1.5 mm, HBR). Intramuscular pressure of the erector spinae muscles and maximal ankle joint torque were unaltered with both models. While neither model increased height to the magnitude observed in microgravity, HDT with balanced traction may be a better model for simulating the body lengthening and back pain experienced in microgravity.




    Full Text Available Nous proposons une approche générale des critères de résistance à la rupture pour des matériaux présentant une dissymétrie de comportement en traction et compression. Elle est basée sur l’égalité des énergies de rupture en traction et compression et repose sur le concept d’endommagement associé à un formalisme énergétique.


    T. N. Mishchenko


    Full Text Available Purpose. Development and substantiation of a new method of structural identification of electrical devices of electric traction systems for both DC and AC current. Methodology. To solve this problem the following methods are used: the methods and techniques of the linear electrical engineering, in particular, the Laplace operator method; the numerical method for solving the integral equation, which is based on the representation of the Wiener-Hopf linear equations system (this allows forming the solutions of the problem in a mathematical form of the correlation and weight functions; the factorization method, which provides certain partition of the correlation functions of the stochastic processes. Findings. It was developed the method of weight function of the electrical devices identification, which can be fully used in the systems of electric traction. As the use example of the developed method it was considered a feeder section of DC electric traction with the single power supply. On this section move two electric locomotives of the type DE 1, they have been identified by the weighting functions. The required currents and voltages of electric locomotives are also formulated in the electric traction network in probabilistic and statistical form, that is, the functions of mathematical expectation and the correlation functions are determined. At this, it is taken into account that the correlation function of the sum of random functions is equal to the sum of the correlation functions of additives, and the correlation function of the integral of a random function is defined as the double integral of the correlation function of the output of a random function. Originality. Firstly, originality consists of the adaption of the developed method of structural identification for the devices of electric traction system. Secondly, it lies in the proper development of the new method of weight function. And finally, it lies in the solution of the Wiener

  19. [Lengthening of residual digit by gradual traction and bone grafting (a report of 143 cases)].

    Hou, C L


    Since 1985, a device for gradual traction was used for lengthening of 143 residual digits in 75 patients. The average lengthening was 2.2 cm. This method is simple, safe, and effective. The advantages of this method over the previously exercised tubed bone graft and other digital lengthening methods are that the digit reconstructed by the gradual traction-lengthening method has the normal cutaneous structure, good sensation function, and better contour. Multiple digits can be reconstructed simultaneously. Because the periosteum at the osteotomy site is kept intact, the long term results are consistent.

  20. Analysis of electromyographic activities of the lumbar erector spinae caused by inversion traction

    Kim, Chung Yoo; Kang, Jong Ho


    [Purpose] The purpose of this study was to analyze changes in the electromyographic activities of the lumbar erector spinae caused by inversion traction in order to verify the relaxation effect. [Subjects and Methods] The subjects included 60 healthy male adults who were equally and randomly assigned to a 30–30° group, a 30–60° group, and a 60–60° group. Inversion traction was performed for six minutes, and the electromyographic activities of the lumbar erector spinae (L2, L4) were measured b...

  1. Effect of combining traction and vibration on back muscles, heart rate and blood pressure.

    Wang, Lizhen; Zhao, Meiya; Ma, Jian; Tian, Shan; Xiang, Pin; Yao, Wei; Fan, Yubo


    Eighty-five percent of the population has experienced low back pain (LBP), which may result in decreasing muscle strength and endurance, functional capacity of the spine, and so on. Traction and vibration are commonly used to relieve the low back pain. The effect of the combing traction and vibration on back muscles, heart rate (HR) and blood pressure (BP) was investigated in this study. Thirty healthy subjects participated in 12 trials lying supine on the spine-combing bed with different tilt angle (0°, 10°, 20° and 30°) and vibration modes (along with the sagittal and coronal axis with 0 Hz, 2 Hz and 12 Hz separately). EMG was recorded during each trial. Power spectral frequency analysis was applied to evaluate muscle fatigue by the shift of median power frequency (MPF). Pulse pressure (PP) was calculated from BP. HR and PP were used to estimate the effect of the combination of traction and vibration on the cardio-vascular system. It was shown that vibration could increase HR and decrease PP. The combination of traction and vibration (2 Hz vibration along Z-axis and 12 Hz vibration along Y-axis) had no significant effect on the cardio-vascular system. The MPF of lumbar erector spinae (LES) and upper trapezius (UT) decreased significantly when the angle reached 20° under the condition of 2 Hz vibration along Z-axis compared with it of 0°. Furthermore, the MPF also decreased significantly compared with it of static mode at 20° for LES and at 30° for UT. However at 12 Hz vibration along Y-axis, the MPF had significant increase when the angle reached 20° in LES and 30° in UT compared to 0°. For LES, the MPF also had significant difference when the angle was increased from 10° to 20°. Therefore, combining 2 Hz vibration along Z-axis and traction (tilt angles that less than 20°) may to reduce muscle fatigue both for LES and UT compared with either vibration or traction alone. The combination of 12 Hz vibration along Y-axis and traction (tilt angles


    G. K. Getman


    Full Text Available Purpose. In general the well known methods for determination of energy saving due to the partial traction engines cut-off based on their comparison to efficiency coefficient or to the power of energy losses do not allow objective estimation of efficiency of these measures and in a number of cases result in erroneous results and errors. The search for new more advanced methods for determination of energy saving at the partial cut-off of the traction engines is needed. Methodology. The method of calculation determination of energy saving when partial cutting-off of the traction engines is offered. It is based on the use of rationality coefficient as the loading mode of the electric power consumption for the measuring instrument of transportation activity. Findings. Using the given mathematical expressions it is possible to determine the energy saving in both the relative and absolute values and set the terms (motion speed and route gradient, under which the energy saving will take place. Originality. The method of the task solving, which is based on the evaluation of energy consumption differences for the compared variants (not on the comparison of efficiency coefficient or differences of power of energy losses is offered. Practical value. The given methodology allows obtaining more exact conclusions in relation to the electric power consumption, as the comparison of energy losses power or the efficiency coefficient does not determine precisely the electric power consumption for traction. Therefore the conclusions based on the comparison of power of energy losses or efficiency coefficient can appear inexact.

  3. Stress analysis in platform-switching implants: a 3-dimensional finite element study.

    Pellizzer, Eduardo Piza; Verri, Fellippo Ramos; Falcón-Antenucci, Rosse Mary; Júnior, Joel Ferreira Santiago; de Carvalho, Paulo Sérgio Perri; de Moraes, Sandra Lúcia Dantas; Noritomi, Pedro Yoshito


    The aim of this study was to evaluate the influence of the platform-switching technique on stress distribution in implant, abutment, and peri-implant tissues, through a 3-dimensional finite element study. Three 3-dimensional mandibular models were fabricated using the SolidWorks 2006 and InVesalius software. Each model was composed of a bone block with one implant 10 mm long and of different diameters (3.75 and 5.00 mm). The UCLA abutments also ranged in diameter from 5.00 mm to 4.1 mm. After obtaining the geometries, the models were transferred to the software FEMAP 10.0 for pre- and postprocessing of finite elements to generate the mesh, loading, and boundary conditions. A total load of 200 N was applied in axial (0°), oblique (45°), and lateral (90°) directions. The models were solved by the software NeiNastran 9.0 and transferred to the software FEMAP 10.0 to obtain the results that were visualized through von Mises and maximum principal stress maps. Model A (implants with 3.75 mm/abutment with 4.1 mm) exhibited the highest area of stress concentration with all loadings (axial, oblique, and lateral) for the implant and the abutment. All models presented the stress areas at the abutment level and at the implant/abutment interface. Models B (implant with 5.0 mm/abutment with 5.0 mm) and C (implant with 5.0 mm/abutment with 4.1 mm) presented minor areas of stress concentration and similar distribution pattern. For the cortical bone, low stress concentration was observed in the peri-implant region for models B and C in comparison to model A. The trabecular bone exhibited low stress that was well distributed in models B and C. Model A presented the highest stress concentration. Model B exhibited better stress distribution. There was no significant difference between the large-diameter implants (models B and C).


    YU. S. Bondarenko


    Full Text Available Purpose. Application of physical modeling as a tool for research of any events or systems is becoming more widespread, including the field of railway transport. At the same time the adequacy of results that can be obtained, depends largely on the similarity degree of the physical model to real system. From the standpoint of the traction asynchronous electric drive (TAED research together with the traction power supply system research, the similarity can not be determined by the direct proportion of the parameters, because the processes nature accompanying the operation of these systems is non-linear. These features should be taken into account in the experimental setup, the basis for constructing of which is establishing of the system similarity that defines the purpose of this paper. Methodology. At the heart of the experimental setup creation laid reproduction of processes of energy transformation in the system of the DC traction power supply. Determination of the similarity degree of the proposed facility to the real system was carried out using the basic theorems of the similarity theory, their additional provisions on the complexity and nonlinear systems, as well as elements of mathematical analysis. Findings. According to the results of work: 1 The block diagram, the energy conversion mechanism of which is similar to the real system was received. This scheme is the basis of experimental setup, built in the future for the study of electromagnetic compatibility of TAED in the structure of DC traction electric power supply system. 2 Similarity of obtained structural scheme with the real system with the mechanism definition of calculating the scaling relations was established. Originality. In the process of establishing the similarity a simplified method for determining the scaling relations for nonlinear systems was suggested. They are identical in their structure components, but have different capacities. Practical value. Experimental


    E. S. Ryabov


    Full Text Available In the article a simulation model of traction direct drive on the basis of inductor motor with the axial magnetic flux realized in the visual programming environment Simulink is considered. At creation of the AIМ model a method block diagrams is used.

  6. The bond-graph design of a motor used for electrical traction

    Adriana Grava


    Full Text Available In this paper the asynchronous motorwith cage, used for electrical traction is studied andanalyzed. For this motor we realized the associatedbond-graph, we pointed out the equations thatdescribe this motor, and we analyzed the electricaland mechanical features of this motor, by using thesimulation program 20 SIM, in order to improve theperformances of this motor even from the early stageof design.

  7. 77 FR 4914 - Consumer Information Regulations; Fees for Use of Traction Skid Pads


    ... use of the traction skid pads at NHTSA's San Angelo Test Facility, formerly called the Uniform Tire Quality Grading Test Facility, in San Angelo, Texas, and by eliminating fees for course monitoring tires... NHTSA's San Angelo Test Facility. 49 CFR 575.104, App. B. Several commercial facilities also...

  8. Wavelet Entropy-Based Traction Inverter Open Switch Fault Diagnosis in High-Speed Railways

    Keting Hu


    Full Text Available In this paper, a diagnosis plan is proposed to settle the detection and isolation problem of open switch faults in high-speed railway traction system traction inverters. Five entropy forms are discussed and compared with the traditional fault detection methods, namely, discrete wavelet transform and discrete wavelet packet transform. The traditional fault detection methods cannot efficiently detect the open switch faults in traction inverters because of the low resolution or the sudden change of the current. The performances of Wavelet Packet Energy Shannon Entropy (WPESE, Wavelet Packet Energy Tsallis Entropy (WPETE with different non-extensive parameters, Wavelet Packet Energy Shannon Entropy with a specific sub-band (WPESE3,6, Empirical Mode Decomposition Shannon Entropy (EMDESE, and Empirical Mode Decomposition Tsallis Entropy (EMDETE with non-extensive parameters in detecting the open switch fault are evaluated by the evaluation parameter. Comparison experiments are carried out to select the best entropy form for the traction inverter open switch fault detection. In addition, the DC component is adopted to isolate the failure Isolated Gate Bipolar Transistor (IGBT. The simulation experiments show that the proposed plan can diagnose single and simultaneous open switch faults correctly and timely.


    何涛; 何岚


    Objective: To observe the therapeutic effect of traction combined with acupuncture on lumbar intervertebral disc herniation (LIDH).Methods:Eighty-three patients diagnosed as LIDH were randomly divided into treatment group (n=42)and control group (n=41).In the treatment group, besides lumbar traction, electroacupuncture at Jiaji (EX-B 2, L3~5), Shenshu (BL 23), Qihai (CV 6), Mingmen (GV 4), Huantiao (GB 30), Chengshan (BL 57) and Yanglingquan (GB 34) was added.In the control group, only lumbar traction was applied.Results: In treatment group, the cure plus markedly effective rate was 80.95% with a total effective rate of 92.86%, while in control group, it was 39.02% with a total effective rate of 80.48%.The therapeutic effect in the treatment group was obviously better than that in the control group (P<0.001).Conclusion: Lumbar traction plus EA can effectively alleviate or even eliminate clinical symptoms and signs of lumbar intervertebral disc herniation.

  10. Performance Availability Assessment of Combined Multi Power Source Traction Drive Considering Real Operational Conditions

    Frenkel Ilia


    Full Text Available The present paper deals with the vehicle’s traction electric drive, consisting of several various electric power sources. One of the main requirements for such systems are the safety and sustainable operations, achieved largely the implementation of an uninterrupted supply of the vehicle’s propulsion system with an electric power.

  11. Operation analysis of AC traction motors in terms of electromagnetic torque capability on sustainable railway vehicles

    Bulucea Cornelia A.


    Full Text Available Sustainable operation of electric railway systems represents a significant purpose nowadays in the development of high power and high speed locomotives and trains. At present, high speed electric vehicles mostly work with three-phase induction motors or three-phase synchronous motors as traction motors. The two electric machine types have different efficiencies at different operation points, and experience differences with respect to safety, speed and power, energy use and exergy efficiency. An important issue that correlates these aspects is the electromagnetic torque developed by an electric traction motor. In order to provide an overview of the technical performance of the operation of sustainable railway systems, a detailed analysis is carried out of the electromagnetic torque capability of AC electric motors utilized as traction motors in modern locomotives of high power and/or high speed. The results of this work may help in enhancing the main criteria for optimising the safe and sustainable operation of electric railway traction systems.

  12. Comparison of the environmental performance of light mechanization and animal traction using a modular LCA approach

    Cerutti, Alessandro K.; Calvo, Angela; Bruun, Sander


    operations. This achievement completely changed food production systems for all populations able to access such technology. Nowadays, animal traction is mainly used in the developing countries, in specific contexts such as mountainous areas due to the difficulties in using tractors, and within farm tourism...

  13. The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.

    Gottlieb, A; Skrinska, V A; O'Hara, P; Boutros, A R; Melia, M; Beck, G J


    Mesenteric traction syndrome consists of sudden tachycardia, hypotension, and cutaneous hyperemia, and frequently occurs during mesenteric traction in patients undergoing abdominal aortic aneurysm (AAA) reconstructive surgery. The etiology and clinical impact of this phenomenon are unknown, but the symptoms suggest a release of vasoactive materials from the mesenteric vascular bed. Thirty-one patients who underwent AAA surgery were studied. Mesenteric traction was accompanied by a decrease in systolic (p = 0.005) and diastolic (p less than 0.05) blood pressures, and in systemic vascular resistance (p less than 0.005), and was accompanied by an increase in heart rate (HR) (p less than 0.005), and cardiac output (p = 0.01). These hemodynamic changes coincided with an increase (p less than 0.001) in plasma concentrations of 6-keto-prostaglandin F1 (6-K-PGF1). No apparent change was found in prostaglandin E2, thromboxane B2, and histamine concentrations. The concentration of 6-K-PGF1 was correlated with diastolic blood pressure (r = -0.52, p less than 0.005) and HR (r = 0.65, p less than 0.001). Cutaneous hyperemia was observed in 58% of the patients. In an additional six patients, who had taken aspirin daily before AAA surgery, no significant changes were observed in the hemodynamic measurements or 6-K-PGF1 concentrations. These data suggest that mesenteric traction syndrome may be mediated at least in part by a selective release of prostacyclin.

  14. [Mobilization and traction therapy for lumbar dorsopathies in obese individuals working in sedentary conditions].

    Drobyshev, V A; Strepetov, O M; Gerasomenko, O N


    Obese individuals working in sedentary conditions, if having neurologic symptoms in lumbar dorsopathies, when subjected to mobilization and traction therapy in rehabilitation complex, demonstrated less pain, increased spine mobility and prospective observations proved longer clinical remission, if compared to standard treatment.

  15. Role of pars plana vitrectomy and membrane peel in vitreomacular traction associated with retinal vasoproliferative tumors

    Castro-Navarro, Verónica; Saktanasate, Jarin; Say, Emil Anthony T.; Chiang, Allen; Shields, Carol Lally


    To report a case of retinal vasoproliferative tumor (VPT) with secondary epiretinal membrane (ERM) formation and vitreo-macular traction managed by pars plana vitrectomy (PPV) and membrane peel. A 29-year-old male was referred for management of decreased vision in the right eye (OD) for 1 week. Presenting visual acuity was 20/50 Snellen feet (ft) OD, and fundus examination showed an ERM associated with a reddish-yellow mass in the inferotemporal quadrant with overlying exudation, hemorrhage, and subretinal fluid consistent with VPT, and cryotherapy was recommended. Two months later, there was complete tumor regression, but there was decreased vision from progressive vitreomacular traction to 20/400 ft. PPV with combined ERM and internal limiting membrane (ILM) peel were performed with resolution of vitreomacular traction and improvement of visual acuity to 20/50 ft at 6 months. PPV with combined ERM and ILM peel is effective for vision loss secondary to ERM and vitreomacular traction associated with retinal VPT. PMID:27843233

  16. Electro-Acupuncture and Block Therapy Combined with Traction for Treatment of Cervical Dysopia

    Jiang Feizhou; Zhu Gengchuang


    @@ Cervical spondylopathy is a commonly and frequently encountered disease characterized by pain in the head, neck and upper extremities, often accompanied with numbness in the extremities and dizziness. The authors have treated 11 cases of cervical spondylopathy whose main symptom is dysopia with electro-acupuncture, block therapy and traction. The quite satisfactory therapeutic results are reported as follows.

  17. Increase of energy efficiency of testing of traction electric machines of direct and pulsating current

    A.M. Afanasov


    Full Text Available The results of the analysis of the effect of the load current of traction electric machines when tested for heating on the total electricity consumption for the test are presented. It is shown that increase of load current at the heating test permits to significantly reduce the consumption of electrical energy, and reduce the testing time without reducing its quality.

  18. Distributed Active Traction Control System Applied to the RoboCup Middle Size League

    José Almeida


    Full Text Available This work addresses the problem of traction control in mobile wheeled robots in the particular case of the RoboCup Middle Size League (MSL. The slip control problem is formulated using simple friction models for ISePorto Team Robots with a differential wheel configuration. Traction was also characterized experimentally in the MSL scenario for relevant game events. This work proposes a hierarchical traction control architecture which relies on local slip detection and control at each wheel, with relevant information being relayed to a higher level responsible for global robot motion control. A dedicated one axis control embedded hardware subsystem allowing complex local control, high frequency current sensing and odometric information procession was developed. This local axis control board is integrated in a distributed system using CAN bus communications. The slipping observer was implemented in the axis control hardware nodes integrated in the ISePorto Robots and was used to control and detect loss of traction. An external vision system was used to perform a qualitative analysis of the slip detection and observer performance results are presented.

  19. Automated image analysis reveals the dynamic 3-dimensional organization of multi-ciliary arrays.

    Galati, Domenico F; Abuin, David S; Tauber, Gabriel A; Pham, Andrew T; Pearson, Chad G


    Multi-ciliated cells (MCCs) use polarized fields of undulating cilia (ciliary array) to produce fluid flow that is essential for many biological processes. Cilia are positioned by microtubule scaffolds called basal bodies (BBs) that are arranged within a spatially complex 3-dimensional geometry (3D). Here, we develop a robust and automated computational image analysis routine to quantify 3D BB organization in the ciliate, Tetrahymena thermophila. Using this routine, we generate the first morphologically constrained 3D reconstructions of Tetrahymena cells and elucidate rules that govern the kinetics of MCC organization. We demonstrate the interplay between BB duplication and cell size expansion through the cell cycle. In mutant cells, we identify a potential BB surveillance mechanism that balances large gaps in BB spacing by increasing the frequency of closely spaced BBs in other regions of the cell. Finally, by taking advantage of a mutant predisposed to BB disorganization, we locate the spatial domains that are most prone to disorganization by environmental stimuli. Collectively, our analyses reveal the importance of quantitative image analysis to understand the principles that guide the 3D organization of MCCs.

  20. Superimposition of 3-dimensional cone-beam computed tomography models of growing patients

    Cevidanes, Lucia H. C.; Heymann, Gavin; Cornelis, Marie A.; DeClerck, Hugo J.; Tulloch, J. F. Camilla


    Introduction The objective of this study was to evaluate a new method for superimposition of 3-dimensional (3D) models of growing subjects. Methods Cone-beam computed tomography scans were taken before and after Class III malocclusion orthopedic treatment with miniplates. Three observers independently constructed 18 3D virtual surface models from cone-beam computed tomography scans of 3 patients. Separate 3D models were constructed for soft-tissue, cranial base, maxillary, and mandibular surfaces. The anterior cranial fossa was used to register the 3D models of before and after treatment (about 1 year of follow-up). Results Three-dimensional overlays of superimposed models and 3D color-coded displacement maps allowed visual and quantitative assessment of growth and treatment changes. The range of interobserver errors for each anatomic region was 0.4 mm for the zygomatic process of maxilla, chin, condyles, posterior border of the rami, and lower border of the mandible, and 0.5 mm for the anterior maxilla soft-tissue upper lip. Conclusions Our results suggest that this method is a valid and reproducible assessment of treatment outcomes for growing subjects. This technique can be used to identify maxillary and mandibular positional changes and bone remodeling relative to the anterior cranial fossa. PMID:19577154

  1. Using Interior Point Method Optimization Techniques to Improve 2- and 3-Dimensional Models of Earth Structures

    Zamora, A.; Gutierrez, A. E.; Velasco, A. A.


    2- and 3-Dimensional models obtained from the inversion of geophysical data are widely used to represent the structural composition of the Earth and to constrain independent models obtained from other geological data (e.g. core samples, seismic surveys, etc.). However, inverse modeling of gravity data presents a very unstable and ill-posed mathematical problem, given that solutions are non-unique and small changes in parameters (position and density contrast of an anomalous body) can highly impact the resulting model. Through the implementation of an interior-point method constrained optimization technique, we improve the 2-D and 3-D models of Earth structures representing known density contrasts mapping anomalous bodies in uniform regions and boundaries between layers in layered environments. The proposed techniques are applied to synthetic data and gravitational data obtained from the Rio Grande Rift and the Cooper Flat Mine region located in Sierra County, New Mexico. Specifically, we improve the 2- and 3-D Earth models by getting rid of unacceptable solutions (those that do not satisfy the required constraints or are geologically unfeasible) given the reduction of the solution space.

  2. Casting of 3-dimensional footwear prints in snow with foam blocks.

    Petraco, Nicholas; Sherman, Hal; Dumitra, Aurora; Roberts, Marcel


    Commercially available foam blocks are presented as an alternative material for the casting and preservation of 3-dimensional footwear impressions located in snow. The method generates highly detailed foam casts of questioned footwear impressions. These casts can be compared to the known outsole standards made from the suspects' footwear. Modification of the commercially available foam casting blocks is simple and fast. The foam block is removed and a piece of cardboard is secured to one side of the block with painter's masking tape. The prepared foam block is then placed back into its original box, marked appropriately, closed and stored until needed. When required the foam block is carefully removed from its storage box and gently placed, foam side down, over the questioned footwear impression. Next, the crime scene technician's hands are placed on top of the cardboard and pressure is gently applied by firmly pressing down onto the impression. The foam cast is removed, dried and placed back into its original container and sealed. The resulting 3D impressions can be directly compared to the outsole of known suspected item(s) of footwear.

  3. Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model

    Tezera, Liku B; Bielecka, Magdalena K; Chancellor, Andrew; Reichmann, Michaela T; Shammari, Basim Al; Brace, Patience; Batty, Alex; Tocheva, Annie; Jogai, Sanjay; Marshall, Ben G; Tebruegge, Marc; Jayasinghe, Suwan N; Mansour, Salah; Elkington, Paul T


    Cell biology differs between traditional cell culture and 3-dimensional (3-D) systems, and is modulated by the extracellular matrix. Experimentation in 3-D presents challenges, especially with virulent pathogens. Mycobacterium tuberculosis (Mtb) kills more humans than any other infection and is characterised by a spatially organised immune response and extracellular matrix remodelling. We developed a 3-D system incorporating virulent mycobacteria, primary human blood mononuclear cells and collagen–alginate matrix to dissect the host-pathogen interaction. Infection in 3-D led to greater cellular survival and permitted longitudinal analysis over 21 days. Key features of human tuberculosis develop, and extracellular matrix integrity favours the host over the pathogen. We optimised multiparameter readouts to study emerging therapeutic interventions: cytokine supplementation, host-directed therapy and immunoaugmentation. Each intervention modulates the host-pathogen interaction, but has both beneficial and harmful effects. This methodology has wide applicability to investigate infectious, inflammatory and neoplastic diseases and develop novel drug regimes and vaccination approaches. DOI: PMID:28063256

  4. Scaffold Free Bio-orthogonal Assembly of 3-Dimensional Cardiac Tissue via Cell Surface Engineering

    Rogozhnikov, Dmitry; O’Brien, Paul J.; Elahipanah, Sina; Yousaf, Muhammad N.


    There has been tremendous interest in constructing in vitro cardiac tissue for a range of fundamental studies of cardiac development and disease and as a commercial system to evaluate therapeutic drug discovery prioritization and toxicity. Although there has been progress towards studying 2-dimensional cardiac function in vitro, there remain challenging obstacles to generate rapid and efficient scaffold-free 3-dimensional multiple cell type co-culture cardiac tissue models. Herein, we develop a programmed rapid self-assembly strategy to induce specific and stable cell-cell contacts among multiple cell types found in heart tissue to generate 3D tissues through cell-surface engineering based on liposome delivery and fusion to display bio-orthogonal functional groups from cell membranes. We generate, for the first time, a scaffold free and stable self assembled 3 cell line co-culture 3D cardiac tissue model by assembling cardiomyocytes, endothelial cells and cardiac fibroblast cells via a rapid inter-cell click ligation process. We compare and analyze the function of the 3D cardiac tissue chips with 2D co-culture monolayers by assessing cardiac specific markers, electromechanical cell coupling, beating rates and evaluating drug toxicity.

  5. Development of a 3-Dimensional Dosimetry System for Leksell Gamma Knife-Perfexion

    Yoon, KyoungJun; Lee, DoHeui; Cho, ByungChul; Lee, SangWook; Ahn, SeungDo


    The purpose of our study is to develop a new, 3-dimensional dosimetry system to verify the accuracy of dose deliveries in Leksell Gamma Knife-Perfexion TM (LGKP) (Elekta, Norcross, GA, USA). The instrument consists of a moving head phantom, an embedded thin active layer and a CCD camera system and was designed to be mounted to LGKP. As an active material concentrically located in the hemispheric head phantom, we choose Gafchromic EBT3 films and Gd2O2S;Tb phosphor sheets for dosimetric measurements. Also, to compensate the lack of backscatter, we located a 1 cm thick PMMA plate downstream of the active layer. The PMMA plate was transparent for scintillation lights to reach the CCD with 1200x1200 pixels by a 5.2 um pitch. Using this system, three hundred images by a 0.2 mm slice gap were acquired under each of three collimator setups, i.e. 4 mm, 8 mm, and 16 mm, respectively. The 2D projected images taken by CCD camera were compared with the dose distributions measured by EBT3 films in the same conditions. All ...

  6. 3-dimensionally integrated photo-detector for neutrino physics and beyond

    Retiere, Fabrice


    Silicon photo-multipliers (SiPMs) are a promising solution for the detection of scintillation light of liquid Xenon and Argon in applications requiring minimum radioactivity content such as neutrinoless double beta decay. The nEXO experiment in particular is planning to use SiPM planes covering 5 m2 for the detection of the light emitted within 5tons of liquid Xenon. The 3-dimensionally digital integrated SiPMs (3DdSiPMs) is an emerging technology that if successful would challenge the analog SiPM technology. Indeed, by combining separate photo-detector and electronics chips within a single package, 3DdSiPM achieve excellent performances for photon counting and time stamping, while dissipating minimum power. Being mostly based on high purity silicon chips, 3DdSiPMs are also expected to achieve excellent radiopurity.The development of 3DdSiPMs for applications in liquid Xenon is expected to progress rapidly by altering the design of the first successful chip assembly developed for medical imaging, focusing on minimizing power dissipation and large area (> cm2) scaling. In this talk we will describe the 3DdSiPM concept a solution for ``light to bit conversion'' within a single package and show how it may revolutionize light detection in noble-gas liquids and beyond.

  7. The Usefulness of 3-Dimensional Virtual Simulation Using Haptics in Training Orotracheal Intubation

    Dong Hoon Lee


    Full Text Available Objectives. Airway control is the most critical treatment. The most common and basic method of endotracheal intubation is orotracheal intubation. To perform accurate and rapid tracheal intubation, appropriate education and training are required. We developed the virtual simulation program utilizing the 3-dimensional display and haptic device to exercise orotracheal intubation, and the educational effect of this program was compared with that of the mannequin method. Method. The control group used airway mannequin and virtual intubation group was trained with new program. We videotaped both groups during objective structured clinical examination (OSCE with airway mannequin. The video was reviewed and scored, and the rate of success and time were calculated. Result. The success rate was 78.6% in virtual intubation group and 93.3% in control group (P=0.273. There was no difference in overall score of OSCE (21.14 ± 4.28 in virtual intubation group and 23.33 ± 4.45 in control group, P=0.188, the time spent in successful intubation (P=0.432, and the number of trials (P>0.101. Conclusion. The virtual simulation with haptics had a similar effect compared with mannequin, but it could be more cost effective and convenient than mannequin training in time and space.

  8. Characterization of 3-dimensional superconductive thin film components for gravitational experiments in space

    Hechler, S.; Nawrodt, R.; Nietzsche, S.; Vodel, W.; Seidel, P. [Friedrich-Schiller-Univ. Jena (Germany). Inst. fuer Festkoerperphysik; Dittus, H. [ZARM, Univ. Bremen (Germany); Loeffler, F. [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany)


    Superconducting quantum interference devices (SQUIDs) are used for high precise gravitational experiments. One of the most impressive experiments is the satellite test of the equivalence principle (STEP) of NASA/ESA. The STEP mission aims to prove a possible violation of Einstein's equivalence principle at an extreme level of accuracy of 1 part in 10{sup 18} in space. In this contribution we present an automatically working measurement equipment to characterize 3-dimensional superconducting thin film components like i.e. pick-up coils and test masses for STEP. The characterization is done by measurements of the transition temperature between the normal and the superconducting state using a special built anti-cryostat. Above all the setup was designed for use in normal LHe transport Dewars. The sample chamber has a volume of 150 cm{sup 3} and can be fully temperature controlled over a range from 4.2 K to 300 K with a resolution of better then 100 mK. (orig.)

  9. Research on the method of cavitations resistance in a piezoelectric pump with 3-dimensional mesh structure

    ZHANG Jian-hui; XIA Qi-xiao; Bai Heng-jun; NING Hong-gang; ONUKI Akiyoshi


    The volume valve piezoelectric pump has received increasing attention from many areas because of its different characteristics such as the absence of chemical pollution and electromagnetic pollution.However,when the pump is working,it produces cavitations and the air bubbles that originate from these will flow out of the pump.Cavitations occurring in the pump will bring out noise and shorten the life of the pump.Furthermore,air bubbles flowing out of the pump will hinder its application in areas such as medical treatment and health care where blood transfusion and infusion are concerned.As a solution to this disadvantage,the CR3DMS (cavitations resistance with 3-dimensional mesh structure) method is developed,which is tested and verified to be effective on not only reducing the occurrence of cavitations and eliminating cavitations' flowing out,but also restraining the emission of noise.In conclusion,the pump with CR3DMS,on the relationship between flow and driving frequency and the relationship between flow and the number of Resistant-Layers in both theory and test,are analyzed.

  10. Assessment and Planning for a Pediatric Bilateral Hand Transplant Using 3-Dimensional Modeling: Case Report.

    Gálvez, Jorge A; Gralewski, Kevin; McAndrew, Christine; Rehman, Mohamed A; Chang, Benjamin; Levin, L Scott


    Children are not typically considered for hand transplantation for various reasons, including the difficulty of finding an appropriate donor. Matching donor-recipient hands and forearms based on size is critically important. If the donor's hands are too large, the recipient may not be able to move the fingers effectively. Conversely, if the donor's hands are too small, the appearance may not be appropriate. We present an 8-year-old child evaluated for a bilateral hand transplant following bilateral amputation. The recipient forearms and model hands were modeled from computed tomography imaging studies and replicated as anatomic models with a 3-dimensional printer. We modified the scale of the printed hand to produce 3 proportions, 80%, 100% and 120%. The transplant team used the anatomical models during evaluation of a donor for appropriate match based on size. The donor's hand size matched the 100%-scale anatomical model hand and the transplant team was activated. In addition to assisting in appropriate donor selection by the transplant team, the 100%-scale anatomical model hand was used to create molds for prosthetic hands for the donor.

  11. PAMELA positron and electron spectra are reproduced by 3-dimensional cosmic-ray modeling

    Gaggero, Daniele; Maccione, Luca; Di Bernardo, Giuseppe; Evoli, Carmelo


    The PAMELA collaboration recently released the $e^+$ absolute spectrum between 1 and 300 GeV in addition to the positron fraction and $e^-$ spectrum previously measured in the same time period. We use the newly developed 3-dimensional upgrade of the DRAGON code and the charge dependent solar modulation HelioProp code to consistently describe those data. We obtain very good fits of all data sets if a $e^+$ + $e^-$ hard extra-component peaked at 1 TeV is added to a softer $e^-$ background and the secondary $e^\\pm$ produced by the spallation of cosmic ray proton and helium nuclei. All sources are assumed to follow a realistic spiral arm spatial distribution. Remarkably, PAMELA data do not display any need of charge asymmetric extra-component. Finally, plain diffusion, or low re-acceleration, propagation models which are tuned against nuclear data, nicely describe PAMELA lepton data with no need to introduce a low energy break in the proton and Helium spectra.

  12. 3-DIMENSIONAL Numerical Modeling on the Combustion and Emission Characteristics of Biodiesel in Diesel Engines

    Yang, Wenming; An, Hui; Amin, Maghbouli; Li, Jing


    A 3-dimensional computational fluid dynamics modeling is conducted on a direct injection diesel engine fueled by biodiesel using multi-dimensional software KIVA4 coupled with CHEMKIN. To accurately predict the oxidation of saturated and unsaturated agents of the biodiesel fuel, a multicomponent advanced combustion model consisting of 69 species and 204 reactions combined with detailed oxidation pathways of methyl decenoate (C11H22O2), methyl-9-decenoate (C11H20O2) and n-heptane (C7H16) is employed in this work. In order to better represent the real fuel properties, the detailed chemical and thermo-physical properties of biodiesel such as vapor pressure, latent heat of vaporization, liquid viscosity and surface tension were calculated and compiled into the KIVA4 fuel library. The nitrogen monoxide (NO) and carbon monoxide (CO) formation mechanisms were also embedded. After validating the numerical simulation model by comparing the in-cylinder pressure and heat release rate curves with experimental results, further studies have been carried out to investigate the effect of combustion chamber design on flow field, subsequently on the combustion process and performance of diesel engine fueled by biodiesel. Research has also been done to investigate the impact of fuel injector location on the performance and emissions formation of diesel engine.

  13. A Novel Method of Orbital Floor Reconstruction Using Virtual Planning, 3-Dimensional Printing, and Autologous Bone.

    Vehmeijer, Maarten; van Eijnatten, Maureen; Liberton, Niels; Wolff, Jan


    Fractures of the orbital floor are often a result of traffic accidents or interpersonal violence. To date, numerous materials and methods have been used to reconstruct the orbital floor. However, simple and cost-effective 3-dimensional (3D) printing technologies for the treatment of orbital floor fractures are still sought. This study describes a simple, precise, cost-effective method of treating orbital fractures using 3D printing technologies in combination with autologous bone. Enophthalmos and diplopia developed in a 64-year-old female patient with an orbital floor fracture. A virtual 3D model of the fracture site was generated from computed tomography images of the patient. The fracture was virtually closed using spline interpolation. Furthermore, a virtual individualized mold of the defect site was created, which was manufactured using an inkjet printer. The tangible mold was subsequently used during surgery to sculpture an individualized autologous orbital floor implant. Virtual reconstruction of the orbital floor and the resulting mold enhanced the overall accuracy and efficiency of the surgical procedure. The sculptured autologous orbital floor implant showed an excellent fit in vivo. The combination of virtual planning and 3D printing offers an accurate and cost-effective treatment method for orbital floor fractures.

  14. Optimal iodine dose for 3-dimensional multidetector-row CT angiography of the liver

    Ichikawa, Tomoaki, E-mail: [Department of Radiology, University of Yamanashi, Yamanashi (Japan); Motosugi, Utaroh; Morisaka, Hiroyuki; Sou, Hironobu; Onohara, Kojiro; Sano, Katsuhiro; Araki, Tsutomu [Department of Radiology, University of Yamanashi, Yamanashi (Japan)


    Purpose: To clarify the optimal iodine dose of contrast material for 3-dimensional multidetector-row CT angiography (3D-MDCTA) of the venous vasculature of the liver using volume rendering technique. Materials and methods: This study included 103 patients who were randomly assigned to 5 contrast-enhanced MDCT protocol groups with different body-weight-tailored doses of contrast material: 500, 600, 630, 650, and 700 mgI/kg body weight. The arterial, portal, and hepatic parenchymal phases were obtained to evaluate enhancement values of the aorta, portal vein, and hepatic vein. Visualization of the portal and hepatic veins on the volume-rendering images of 3D-MDCTA was evaluated using a 5-point grade. Dunnett's test was used to compare the mean enhancement value and mean grades of image quality (700 mgI/kg dose group was control). Results: The mean enhancement values of portal and hepatic vein in the group with 500 and 600 mgI/kg were significantly lower than those of the control group. During visual assessment, a significantly lower mean grades were observed in 500 mgI/kg groups for the portal vein, and 500 and 600 mgI/kg groups for hepatic vein. There were no significant intergroup differences in mean enhancement values and visual assessment among the groups using 630 mgI/kg or more. Conclusion: Iodine doses of 630 mgI/kg was recommended for 3D-MDCTA.

  15. A 3-Dimensional discrete fracture network generator to examine fracture-matrix interaction using TOUGH2

    Ito, Kazumasa; Yongkoo, Seol


    Water fluxes in unsaturated, fractured rock involve the physical processes occurring at fracture-matrix interfaces within fracture networks. Modeling these water fluxes using a discrete fracture network model is a complicated effort. Existing preprocessors for TOUGH2 are not suitable to generate grids for fracture networks with various orientations and inclinations. There are several 3-D discrete-fracture-network simulators for flow and transport, but most of them do not capture fracture-matrix interaction. We have developed a new 3-D discrete-fracture-network mesh generator, FRACMESH, to provide TOUGH2 with information about the fracture network configuration and fracture-matrix interactions. FRACMESH transforms a discrete fracture network into a 3 dimensional uniform mesh, in which fractures are considered as elements with unique rock material properties and connected to surrounding matrix elements. Using FRACMESH, individual fractures may have uniform or random aperture distributions to consider heterogeneity. Fracture element volumes and interfacial areas are calculated from fracture geometry within individual elements. By using FRACMESH and TOUGH2, fractures with various inclinations and orientations, and fracture-matrix interaction, can be incorporated. In this paper, results of flow and transport simulations in a fractured rock block utilizing FRACMESH are presented.

  16. A 3-dimensional rigid cluster thorax model for kinematic measurements during gait.

    Kiernan, D; Malone, A; O'Brien, T; Simms, C K


    The trunk has been shown to work as an active segment rather than a passenger unit during gait and it is felt that trunk kinematics should be given more consideration during gait assessment. While 3-dimensional assessment of the thorax with respect to the pelvis and laboratory can provide a comprehensive description of trunk movement, the majority of existing 3-D thorax models demonstrate shortcomings such as the need for multiple skin marker configurations, difficult landmark identification and practical issues for assessment on female subjects. A small number of studies have used rigid cluster models to quantify thorax movement, however the models and points of attachment are not well described and validation rarely considered. The aim of this study was to propose an alternative rigid cluster 3-D thorax model to quantify movement during gait and provide validation of this model. A rigid mount utilising active markers was developed and applied over the 3rd thoracic vertebra, previously reported as an area of least skin movement artefact on the trunk. The model was compared to two reference thorax models through simultaneous recording during gait on 15 healthy subjects. Excellent waveform similarity was demonstrated between the proposed model and the two reference models (CMC range 0.962-0.997). Agreement of discrete parameters was very-good to excellent. In addition, ensemble average graphs demonstrated almost identical curve displacement between models. The results suggest that the proposed model can be confidently used as an alternative to other thorax models in the clinical setting.

  17. Characterization of the 3-dimensional microstructure of a graphite negative electrode from a Li-ion battery

    Shearing, P.R.; Howard, L.E.; Jørgensen, Peter Stanley


    The 3-dimensional microstructure of a porous electrode from a lithium-ion battery has been characterized for the first time. We use X-ray tomography to reconstruct a 43 × 348 × 478 μm sample volume with voxel dimensions of 480 nm, subsequent division of the reconstructed volumes into sub-volumes ......The 3-dimensional microstructure of a porous electrode from a lithium-ion battery has been characterized for the first time. We use X-ray tomography to reconstruct a 43 × 348 × 478 μm sample volume with voxel dimensions of 480 nm, subsequent division of the reconstructed volumes into sub...

  18. Brachial plexus palsy caused by halo traction before posterior correction in patients with severe scoliosis

    QIAN Bang-ping; QIU Yong; WANG Bin; YU Yang; ZHU Ze-zhang


    Objective: To explore the clinical features and treatment results of brachial plexus palsy caused by halo traction before posterior correction in patients with severe scoliosis.Methods: A total of 300 cases of severe scoliosis received halo traction before posterior correction in our department from July 1997 to November 2004. Among them, 7 cases were complicated with brachial plexus palsy.The average Cobb angle was 110° (range, 90°-135°).Diagnoses were made as idiopathic scoliosis in 1 case,congenital scoliosis in 3 cases, and neuromuscular scoliosis in 3 cases. Additionally, diastematomyelia and tethered cord syndrome were found in 3 cases and thoracolumbar kyphosis in 2 cases. Weight of traction was immediately reduced when the patient developed any abnormal neurological symptoms in the upper extremity, and rehabilitation training was undertaken. Simultaneously,neurotrophic pharmacotherapy was applied, and the neurological function restoration of the upper limbs and the recovery time were documented.Results: Traction was used for an average of 3.5 weeks (range, 2-6 weeks) before spinal fusion for these 7 patients. The average traction weight was 8 kg, which was 19% on average (range, 13%-26%) of the average body weight (40.2 kg). These 7 patients had long and thin body configuration with a mean height of 175 cm. The duration between symptoms of brachial plexus paralysis and the diagnosis was 1-3 hours. All of these 7 patients presented various degrees of numbness in the ulnar side of the hand and forearm. Median nerve paresis was found in 3 cases and ulnar nerve paresis in 4 cases. Complete recovery of the neurological function had been achieved by the end of three months.Conclusions: The clinical features of brachial plexus palsy caused by halo traction include median nerve paresis,ulnar nerve paralysis, and numbness in the ulnar side of the hand and forearm, which may be due to the injury of the inferior part of the brachial plexus, i.e. , damage of Cs and


    V. E. Bondarenko


    Full Text Available Innovative scenarios of reliable energy supply of transportation process aimed at reducing the specific energy consumption and increase energy efficiency of the systems of electric traction. The paper suggests innovative energy saving directions in traction networks of railways and new circuit solutions accessing traction substations in energy systems networks, ensure energy security of the transportation process. To ensure the energy security of rail transport special schemes were developed to propose the concept of external power traction substations, which would increase the number of connections to the networks of 220 – 330 kV, as well as the creation of transport and energy corridors, development of its own supply of electric networks of 110 kV substations and mobile RP-110 kV of next generation. Therefore, the investment program of the structures owned by the Ukrainian Railways (Ukrzaliznytsia need to be synchronized in their technological characteristics, as well as the criteria of reliability and quality of power supply with the same external energy investment programs. It is found that without any load on left or right supplying arm one of two less loaded phases of traction transformer begins generating specific modes in the supplying three-phase line. Thus, modes of mobile substation cause leakage in one of the phases of the supply line of traction transformers of active-capacitive current, and as a result generating energy in the main power line of 154 kV, which is fixed and calculated by electricity meters. For these three phase mode supply network is necessary to use 1st algorithm, i.e. taking into account the amount of electricity as the energy in all phases. For effective application of reactive power compensation devices in the AC traction power supply systems it is proposed to develop regulatory documentation on necessity of application and the order of choice of parameters and placement of compensation systems taking into


    M. O. Kostin


    Full Text Available Purpose. Theoretical justification of the "field" approach (based on electromagnetic field to the transmission and losses of power in the devices of traction power supply systems and electric rolling stock. Methodology. The methods of electromagnetic field theory and, in particular, the theory and practice of electromagnetic energy transmission based on the concept of the Poynting vector and elements of the theory of propagation, reflection and refraction of plane electromagnetic waves were used. Findings. Theoretical studies of electromagnetic energy transmission from the traction substation to the electric rolling stock through dielectric (air surrounding traction network: between the contact wire and the rail were carried out. It is proposed strategic designing "squat" (low types of electric rolling stock. The components of electric energy flow through the roof of electric rolling stock and its frontal part of the body were estimated. This allows reliable etimating active power losses in electric traction system. To compensate the reactive power consumed by electric rolling stock, which is conditioned by standing waves, it is proposed (for extinction of the the last to develop and put in front of electric rolling stock the layer of particular environment with the necessary parameters. Originality. The "field" principle of the power transmission analysis and its losses arising in electric traction system was first proposed. The laws of motion of electromagnetic energy flows through the roof and the frontal part of the body of electric rolling stock were established. Practical value. An expression of the absolute value of the Poynting vector in the points of dielectric (air between the contact wire and the rail was obtained. This allows assessing the highest density of energy, which is transferred to the time unit and predicting the main dimensions of the unit of electric rolling stock. The energy indices of the roof of electric rolling stock

  1. Study of the asynchronous traction drive's operating modes by computer simulation. Part 1: Problem formulation and computer model



    Full Text Available In this paper, the problems arising from the design of electric locomotives with asynchronous traction drive (with three-phase AC induction motors are considered as including the debugging of control algorithms. The electrical circuit provides the individual (by axle control of traction motors. This allows realizing the operational disconnection/connection of one or more axles in the automatic mode, with account of actual load. In perspective, the evaluation of locomotive's energy efficiency at the realization of various control algorithms must be obtained. Another objective is to research the dynamic processes in various modes of the electric locomotive operation (start and acceleration, traction regime, coasting movement, wheel-slide protection, etc. To solve these problems, a complex computer model based on the representation of AC traction drive as controlled electromechanical system, is developed in Part 1. The description of methods applied in modeling of traction drive elements (traction motors, power converters, control systems, as well as of mechanical part and of "wheel-rail" contact, is given. The control system provides the individual control of the traction motors. Part 2 of the paper focuses on the results of dynamic processes modeling in various modes of electric locomotive operation.

  2. Diagnostic performance of direct traction MR arthrography of the hip: detection of chondral and labral lesions with arthroscopic comparison

    Schmaranzer, Florian; Klauser, Andrea; Henninger, Benjamin [Medical University Innsbruck, Department of Radiology, Innsbruck (Austria); Kogler, Michael; Schmaranzer, Ehrenfried [District Hospital St. Johann in Tyrol, Department of Radiology, St. Johann in Tyrol (Austria); Forstner, Thomas [Johannes Keppler University, Department for Applied Systems Research and Statistics, Linz (Austria); Reichkendler, Markus [District Hospital St. Johann in Tyrol, Department of Orthopedic Surgery, St. Johann in Tyrol (Austria)


    To assess diagnostic performance of traction MR arthrography of the hip in detection and grading of chondral and labral lesions with arthroscopic comparison. Seventy-five MR arthrograms obtained ± traction of 73 consecutive patients (mean age, 34.5 years; range, 14-54 years) who underwent arthroscopy were included. Traction technique included weight-adapted traction (15-23 kg), a supporting plate for the contralateral leg, and intra-articular injection of 18-27 ml (local anaesthetic and contrast agent). Patients reported on neuropraxia and on pain. Two blinded readers independently assessed femoroacetabular cartilage and labrum lesions which were correlated with arthroscopy. Interobserver agreement was calculated using κ values. Joint distraction ± traction was evaluated in consensus. No procedure had to be stopped. There were no cases of neuropraxia. Accuracy for detection of labral lesions was 92 %/93 %, 91 %/83 % for acetabular lesions, and 92 %/88 % for femoral cartilage lesions for reader 1/reader 2, respectively. Interobserver agreement was moderate (κ = 0.58) for grading of labrum lesions and substantial (κ = 0.7, κ = 0.68) for grading of acetabular and femoral cartilage lesions. Joint distraction was achieved in 72/75 and 14/75 hips with/without traction, respectively. Traction MR arthrography safely enabled accurate detection and grading of labral and chondral lesions. (orig.)


    A. M. Afanasov


    Full Text Available Purpose. Loading-back systems are used for post-maintenance acceptance tests of electric traction motors of electric rolling stock (ERS in mainline and industrial transport. The aim of the research is justification of choice method of the rational loading-back parameters of traction electric motors during the tests for heating. Methodology. At the heart of the choice method justification of the rational loading-back parameters is a theory of heating the homogeneous solid body and well-known methods of heating calculations of traction electric machines. Findings. Expediency of heating tests for electric traction motors at load currents equal to the starting current (for ERS of mainline transport or fifteen minutes current (for ERS of industrial transport was substantiated. It was shown that this increase of load current will reduce the electricity costs of the tests for 20–30% and shorten the tests duration for three–four times while ensuring the corrected power minimum of energy sources in loading-back system. Originality. It is shown that the energy costs for heating tests of the traction motors can be reduced by both the increasing the energy efficiency of the loading-back system and by the optimizing of loading mode of traction electric machines. Choice technique of rational modes of loading-back for electric traction motors of rolling stock in mainline and industrial transport was grounded. Practical value. Load current increase of traction electric motors during their tests for heating will reduce the total electricity consumption for the acceptance tests, reduce test time and total material costs for repair of the electric traction motors of rolling stock in mainline and industrial transport.

  4. [Tension force in dynamic splints made of neoprene].

    Punsola-Izard, V; Rouzaud, J C; Thomas, D; Lluch; Garcia-Elias


    Dynamic splints are the most difficult ortheses to make. Unrestricted finger joint mobility is usually prevented by the size of their components. Ortheses made out of neoprene material have the advantage of being pliable and at the same time can be constructed as dynamic splints. Neoprene material elasticity allows conforming it into a tube that can be fitted over a finger, spreading uniform pressure. A traction slip can be cemented to the neoprene finger tube. With neoprene splints, lever arms are more efficient. Their tubular design applies and spreads traction and countertraction forces in all directions. Neoprene material's elasticity contributes in reducing edema formation as well as distributes forces applied to the finger over a large area. The risk of excessive pressure is the only drawback of an elastic tubular design, it may cause pain and tissue ischemia. A meticulous tailoring prevents this potential risk.

  5. Holographic and cephalometric study of the relationship between craniofacial morphology and the initial reactions to high-pull headgear traction.

    Duterloo, H S; Kragt, G; Algra, A M


    Eight macerated human child skulls with a dental age of approximately 9.5 years (mixed dentition) were consecutively subjected to an experimental standardized high-pull headgear traction system attached to the maxilla at the first permanent molar area via an immovable acrylic resin splint covering all teeth. This system produced tensile forces from 0.5 to 3.5 N (1 N = 0.10 kg) per side. Laser holography was used to measure displacements in a three-dimensional coordinate system. Displacements varied in direction. In addition, conventional cephalometric analysis of standardized lateral roentgen cephalograms was performed. Displacements and cephalometric data were then compared. Results indicate that the direction of initial displacements of bones of the facial skeleton bears a definite relationship to the morphology of the individual skull. In skulls with high divergency values (large angles, sella-nasion-occlusal plane, sella-nasion-mandibular plane), displacements are in a backward and posterior downward direction; in skulls with a small sella-nasion-occlusal plane angle, backward displacements occur in a direction almost parallel to the occlusal plane.

  6. An integrated 3-Dimensional Genome Modeling Engine for data-driven simulation of spatial genome organization.

    Szałaj, Przemysław; Tang, Zhonghui; Michalski, Paul; Pietal, Michal J; Luo, Oscar J; Sadowski, Michał; Li, Xingwang; Radew, Kamen; Ruan, Yijun; Plewczynski, Dariusz


    ChIA-PET is a high-throughput mapping technology that reveals long-range chromatin interactions and provides insights into the basic principles of spatial genome organization and gene regulation mediated by specific protein factors. Recently, we showed that a single ChIA-PET experiment provides information at all genomic scales of interest, from the high-resolution locations of binding sites and enriched chromatin interactions mediated by specific protein factors, to the low resolution of nonenriched interactions that reflect topological neighborhoods of higher-order chromosome folding. This multilevel nature of ChIA-PET data offers an opportunity to use multiscale 3D models to study structural-functional relationships at multiple length scales, but doing so requires a structural modeling platform. Here, we report the development of 3D-GNOME (3-Dimensional Genome Modeling Engine), a complete computational pipeline for 3D simulation using ChIA-PET data. 3D-GNOME consists of three integrated components: a graph-distance-based heat map normalization tool, a 3D modeling platform, and an interactive 3D visualization tool. Using ChIA-PET and Hi-C data derived from human B-lymphocytes, we demonstrate the effectiveness of 3D-GNOME in building 3D genome models at multiple levels, including the entire genome, individual chromosomes, and specific segments at megabase (Mb) and kilobase (kb) resolutions of single average and ensemble structures. Further incorporation of CTCF-motif orientation and high-resolution looping patterns in 3D simulation provided additional reliability of potential biologically plausible topological structures.

  7. Realization of masticatory movement by 3-dimensional simulation of the temporomandibular joint and the masticatory muscles.

    Park, Jong-Tae; Lee, Jae-Gi; Won, Sung-Yoon; Lee, Sang-Hee; Cha, Jung-Yul; Kim, Hee-Jin


    Masticatory muscles are closely involved in mastication, pronunciation, and swallowing, and it is therefore important to study the specific functions and dynamics of the mandibular and masticatory muscles. However, the shortness of muscle fibers and the diversity of movement directions make it difficult to study and simplify the dynamics of mastication. The purpose of this study was to use 3-dimensional (3D) simulation to observe the functions and movements of each of the masticatory muscles and the mandible while chewing. To simulate the masticatory movement, computed tomographic images were taken from a single Korean volunteer (30-year-old man), and skull image data were reconstructed in 3D (Mimics; Materialise, Leuven, Belgium). The 3D-reconstructed masticatory muscles were then attached to the 3D skull model. The masticatory movements were animated using Maya (Autodesk, San Rafael, CA) based on the mandibular motion path. During unilateral chewing, the mandible was found to move laterally toward the functional side by contracting the contralateral lateral pterygoid and ipsilateral temporalis muscles. During the initial mouth opening, only hinge movement was observed at the temporomandibular joint. During this period, the entire mandible rotated approximately 13 degrees toward the bicondylar horizontal plane. Continued movement of the mandible to full mouth opening occurred simultaneously with sliding and hinge movements, and the mandible rotated approximately 17 degrees toward the center of the mandibular ramus. The described approach can yield data for use in face animation and other simulation systems and for elucidating the functional components related to contraction and relaxation of muscles during mastication.

  8. Estimating the costs of intensity-modulated and 3-dimensional conformal radiotherapy in Ontario

    Yong, J.H.E.; McGowan, T.; Redmond-Misner, R.; Beca, J.; Warde, P.; Gutierrez, E.; Hoch, J.S.


    Background Radiotherapy is a common treatment for many cancers, but up-to-date estimates of the costs of radiotherapy are lacking. In the present study, we estimated the unit costs of intensity-modulated radiotherapy (imrt) and 3-dimensional conformal radiotherapy (3D-crt) in Ontario. Methods An activity-based costing model was developed to estimate the costs of imrt and 3D-crt in prostate cancer. It included the costs of equipment, staff, and supporting infrastructure. The framework was subsequently adapted to estimate the costs of radiotherapy in breast cancer and head-and-neck cancer. We also tested various scenarios by varying the program maturity and the use of volumetric modulated arc therapy (vmat) alongside imrt. Results From the perspective of the health care system, treating prostate cancer with imrt and 3D-crt respectively cost $12,834 and $12,453 per patient. The cost of radiotherapy ranged from $5,270 to $14,155 and was sensitive to analytic perspective, radiation technique, and disease site. Cases of head-and-neck cancer were the most costly, being driven by treatment complexity and fractions per treatment. Although imrt was more costly than 3D-crt, its cost will likely decline over time as programs mature and vmat is incorporated. Conclusions Our costing model can be modified to estimate the costs of 3D-crt and imrt for various disease sites and settings. The results demonstrate the important role of capital costs in studies of radiotherapy cost from a health system perspective, which our model can accommodate. In addition, our study established the need for future analyses of imrt cost to consider how vmat affects time consumption. PMID:27330359

  9. Novel Radiobiological Gamma Index for Evaluation of 3-Dimensional Predicted Dose Distribution

    Sumida, Iori, E-mail: [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Yamaguchi, Hajime; Kizaki, Hisao; Aboshi, Keiko; Tsujii, Mari; Yoshikawa, Nobuhiko; Yamada, Yuji [Department of Radiation Oncology, NTT West Osaka Hospital, Osaka (Japan); Suzuki, Osamu; Seo, Yuji [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Isohashi, Fumiaki [Department of Radiation Oncology, NTT West Osaka Hospital, Osaka (Japan); Yoshioka, Yasuo [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Ogawa, Kazuhiko [Department of Radiation Oncology, NTT West Osaka Hospital, Osaka (Japan)


    Purpose: To propose a gamma index-based dose evaluation index that integrates the radiobiological parameters of tumor control (TCP) and normal tissue complication probabilities (NTCP). Methods and Materials: Fifteen prostate and head and neck (H&N) cancer patients received intensity modulated radiation therapy. Before treatment, patient-specific quality assurance was conducted via beam-by-beam analysis, and beam-specific dose error distributions were generated. The predicted 3-dimensional (3D) dose distribution was calculated by back-projection of relative dose error distribution per beam. A 3D gamma analysis of different organs (prostate: clinical [CTV] and planned target volumes [PTV], rectum, bladder, femoral heads; H&N: gross tumor volume [GTV], CTV, spinal cord, brain stem, both parotids) was performed using predicted and planned dose distributions under 2%/2 mm tolerance and physical gamma passing rate was calculated. TCP and NTCP values were calculated for voxels with physical gamma indices (PGI) >1. We propose a new radiobiological gamma index (RGI) to quantify the radiobiological effects of TCP and NTCP and calculate radiobiological gamma passing rates. Results: The mean RGI gamma passing rates for prostate cases were significantly different compared with those of PGI (P<.03–.001). The mean RGI gamma passing rates for H&N cases (except for GTV) were significantly different compared with those of PGI (P<.001). Differences in gamma passing rates between PGI and RGI were due to dose differences between the planned and predicted dose distributions. Radiobiological gamma distribution was visualized to identify areas where the dose was radiobiologically important. Conclusions: RGI was proposed to integrate radiobiological effects into PGI. This index would assist physicians and medical physicists not only in physical evaluations of treatment delivery accuracy, but also in clinical evaluations of predicted dose distribution.

  10. New stereoacuity test using a 3-dimensional display system in children.

    Sang Beom Han

    Full Text Available The previously developed 3-dimensional (3D display stereoacuity tests were validated only at distance. We developed a new stereoacuity test using a 3D display that works both at near and distance and evaluated its validity in children with and without strabismus. Sixty children (age range, 6 to 18 years with variable ranges of stereoacuity were included. Side-by-side randot images of 4 different simple objects (star, circle, rectangle, and triangle with a wide range of crossed horizontal disparities (3000 to 20 arcsec were randomly displayed on a 3D monitor with MATLAB (Matworks, Inc., Natick, MA, USA and were presented to subjects wearing shutter glasses at 0.5 m and 3 m. The 3D image was located in front of (conventional or behind (proposed the background image on the 3D monitor. The results with the new 3D stereotest (conventional and proposed were compared with those of the near and distance Randot stereotests. At near, the Bland-Altman plots of the conventional and proposed 3D stereotest did not show significant difference, both of which were poorer than the Randot test. At distance, the results of the proposed 3D stereotest were similar to the Randot test, but the conventional 3D stereotest results were better than those of the other two tests. The results of the proposed 3D stereotest and Randot stereotest were identical in 83.3% at near and 88.3% at distance. More than 95% of subjects showed concordance within 2 grades between the 2 tests at both near and distance. In conclusion, the newly proposed 3D stereotest shows good concordance with the Randot stereotests in children with and without strabismus.

  11. Design of biphasic polymeric 3-dimensional fiber deposited scaffolds for cartilage tissue engineering applications.

    Moroni, L; Hendriks, J A A; Schotel, R; de Wijn, J R; van Blitterswijk, C A


    This report describes a novel system to create rapid prototyped 3-dimensional (3D) fibrous scaffolds with a shell-core fiber architecture in which the core polymer supplies the mechanical properties and the shell polymer acts as a coating providing the desired physicochemical surface properties. Poly[(ethylene oxide) terephthalate-co-poly(butylene) terephthalate] (PEOT/PBT) 3D fiber deposited (3DF) scaffolds were fabricated and examined for articular cartilage tissue regeneration. The shell polymer contained a higher molecular weight of the initial poly(ethylene glycol) (PEG) segments used in the copolymerization and a higher weight percentage of the PEOT domains compared with the core polymer. The 3DF scaffolds entirely produced with the shell or with the core polymers were also considered. After 3 weeks of culture, scaffolds were homogeneously filled with cartilage tissue, as assessed by scanning electron microscopy. Although comparable amounts of entrapped chondrocytes and of extracellular matrix formation were found for all analyzed scaffolds, chondrocytes maintained their rounded shape and aggregated during the culture period on shell-core 3DF scaffolds, suggesting a proper cell differentiation into articular cartilage. This finding was also observed in the 3DF scaffolds fabricated with the shell composition only. In contrast, cells spread and attached on scaffolds made simply with the core polymer, implying a lower degree of differentiation into articular cartilaginous tissue. Furthermore, the shell-core scaffolds displayed an improved dynamic stiffness as a result of a "prestress" action of the shell polymer on the core one. In addition, the dynamic stiffness of the constructs increased compared with the stiffness of the bare scaffolds before culture. These findings suggest that shell-core 3DF PEOT/PBT scaffolds with desired mechanical and surface properties are a promising solution for improved cartilage tissue engineering.

  12. Using a clinical protocol for orthognathic surgery and assessing a 3-dimensional virtual approach: current therapy.

    Quevedo, Luis A; Ruiz, Jessica V; Quevedo, Cristobal A


    Oral and maxillofacial surgeons who perform orthognathic surgery face major changes in their practices, and these challenges will increase in the near future, because the extraordinary advances in technology applied to our profession are not only amazing but are becoming the standard of care as they promote improved outcomes for our patients. Orthognathic surgery is one of the favorite areas of practicing within the scope of practice of an oral and maxillofacial surgeon. Our own practice in orthognathic surgery has completed over 1,000 surgeries of this type. Success is directly related to the consistency and capability of the surgical-orthodontic team to achieve predictable, stable results, and our hypothesis is that a successful result is directly related to the way we take our records and perform diagnosis and treatment planning following basic general principles. Now that we have the opportunity to plan and treat 3-dimensional (3D) problems with 3D technology, we should enter into this new era with appropriate standards to ensure better results, instead of simply enjoying these new tools, which will clearly show not only us but everyone what we do when we perform orthognathic surgery. Appropriate principles need to be taken into account when implementing this new technology. In other words, new technology is welcome, but we do not have to reinvent the wheel. The purpose of this article is to review the current protocol that we use for orthognathic surgery and compare it with published protocols that incorporate new 3D and virtual technology. This report also describes our approach to this new technology.

  13. Reproducibility of a 3-dimensional gyroscope in measuring shoulder anteflexion and abduction

    Penning Ludo I F


    Full Text Available Abstract Background Few studies have investigated the use of a 3-dimensional gyroscope for measuring the range of motion (ROM in the impaired shoulder. Reproducibility of digital inclinometer and visual estimation is poor. This study aims to investigate the reproducibility of a tri axial gyroscope in measurement of anteflexion, abduction and related rotations in the impaired shoulder. Methods Fifty-eight patients with either subacromial impingement (27 or osteoarthritis of the shoulder (31 participated. Active anteflexion, abduction and related rotations were measured with a tri axial gyroscope according to a test retest protocol. Severity of shoulder impairment and patient perceived pain were assessed by the Disability of Arm Shoulder and Hand score (DASH and the Visual Analogue Scale (VAS. VAS scores were recorded before and after testing. Results In two out of three hospitals patients with osteoarthritis (n = 31 were measured, in the third hospital patients with subacromial impingement (n = 27. There were significant differences among hospitals for the VAS and DASH scores measured before and after testing. The mean differences between the test and retest means for anteflexion were −6 degrees (affected side, 9 (contralateral side and for abduction 15 degrees (affected side and 10 degrees (contralateral side. Bland & Altman plots showed that the confidence intervals for the mean differences fall within −6 up to 15 degrees, individual test - retest differences could exceed these limits. A simulation according to ‘Generalizability Theory’ produces very good coefficients for anteflexion and related rotation as a comprehensive measure of reproducibility. Optimal reproducibility is achieved with 2 repetitions for anteflexion. Conclusions Measurements were influenced by patient perceived pain. Differences in VAS and DASH might be explained by different underlying pathology. These differences in shoulder pathology however did not alter

  14. Delineation of right and left lobe of the liver accessed by 3-dimensional CT images

    Teleuhan, Nadira [Hiroshima Univ. (Japan). Graduate School of Biomedical Sciences


    Adequate delineation of right and left liver lobes is very important especially in partial hepatectomy. We analyzed the sub-volumes of middle hepatic vein (MHV) draining area divided by the Cantlie's plane and MHV plane using CT 3-dimensional images. We examined 10 donor candidates for liver transplantation with multi-detector-row CT. Three-dimensional rendering images of the liver parenchyma and the hepatic vein were created. After identifying hepatic vein draining area, liver volume was divided into three hepatic vein-draining areas. The MHV draining area was divided by two different planes, Cant lie's plane and MHV plane, and draining volumes from right and left lobes were calculated. Total liver volume and right, middle, left hepatic vein-draining volume (ratio of total liver volume) were 1472{+-}259 ml, 708{+-}150 ml (48{+-}10%), 414{+-}175 ml (28{+-}12%), 350{+-}110 ml (24{+-}7%) divided by Cant lie's plane, draining volumes from right and left lobes were 306{+-}200 ml (21{+-}14%) and 108{+-}69 ml (7{+-}5%). Divided by MHV plane, draining volumes from right and left lobes were 198{+-}123 ml (13{+-}8%) and 216{+-}73 ml (15{+-}5%). Volume difference of two sub-volumes was 108{+-}92 ml (7{+-}6%, 0-270 ml). The proportion of MHV draining volume had a considerable dispersion among 10 persons. In most of cases the draining volumes from the left lobe were bigger than those from right lobes. (author)

  15. Albedo and heat transport in 3-dimensional model simulations of the early Archean climate

    H. Kienert


    Full Text Available At the beginning of the Archean eon (ca. 3.8 billion yr ago, the Earth's climate state was significantly different from today due to the lower solar luminosity, smaller continental fraction, higher rotation rate and, presumably, significantly larger greenhouse gas concentrations. All these aspects play a role in solutions to the "faint young Sun problem" which must explain why the ocean surface was not fully frozen at that time. Here, we present 3-dimensional model simulations of climate states that are consistent with early Archean boundary conditions and have different CO2 concentrations, aiming at an understanding of the fundamental characteristics of the early Archean climate system. We focus on three states: one of them is ice-free, one has the same mean surface air temperature of 288 K as today's Earth and the third one is the coldest stable state in which there is still an area with liquid surface water (i.e. the critical state at the transition to a "snowball Earth". We find a reduction in meridional heat transport compared to today which leads to a steeper latitudinal temperature profile and has atmospheric as well as oceanic contributions. Ocean surface velocities are largely zonal, and the strength of the atmospheric meridional circulation is significantly reduced in all three states. These aspects contribute to the observed relation between global mean temperature and albedo, which we suggest as a parameterisation of the ice-albedo feedback for 1-dimensional model simulations of the early Archean and thus the faint young Sun problem.

  16. A customized bolus produced using a 3-dimensional printer for radiotherapy.

    Shin-Wook Kim

    Full Text Available OBJECTIVE: Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect. In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps. Hence, we fabricated a customized bolus using a 3-dimensional (3D printer and evaluated its feasibility for radiotherapy. METHODS: We designed two kinds of bolus for production on a 3D printer, one of which was the 3D printed flat bolus for the Blue water phantom and the other was a 3D printed customized bolus for the RANDO phantom. The 3D printed flat bolus was fabricated to verify its physical quality. The resulting 3D printed flat bolus was evaluated by assessing dosimetric parameters such as D1.5 cm, D5 cm, and D10 cm. The 3D printed customized bolus was then fabricated, and its quality and clinical feasibility were evaluated by visual inspection and by assessing dosimetric parameters such as Dmax, Dmin, Dmean, D90%, and V90%. RESULTS: The dosimetric parameters of the resulting 3D printed flat bolus showed that it was a useful dose escalating material, equivalent to a commercially available flat bolus. Analysis of the dosimetric parameters of the 3D printed customized bolus demonstrated that it is provided good dose escalation and good contact with the irregular surface of the RANDO phantom. CONCLUSIONS: A customized bolus produced using a 3D printer could potentially replace commercially available flat boluses.

  17. Low energy scattering parameters from the solutions of the non-relativistic Yukawa model on a 3-dimensional lattice

    De Soto, F


    The numerical solutions of the non-relativistic Yukawa model on a 3-dimensional size lattice with periodic boundary conditions are obtained. The possibility to extract the corresponding -- infinite space -- low energy parameters and bound state binding energies from eigensates computed at finite lattice size is discussed.

  18. Integrated Cooling System for Induction Motor Traction Drives, CARAT Program Phase Two Final Report

    Konrad, Charles E. [VPT, Inc., Blacksburg, VA (United States)


    This Program is directed toward improvements in electric vehicle/hybrid electric vehicle traction systems, and in particular, the development of a low cost, highly efficient, compact traction motor-controller system targeted for high volume automotive use. Because of the complex inter-relationships between the motor and the controller, the combination of motor and controller must be considered as a system in the design and evaluation of overall cost and performance. The induction motor is ideally suited for use as a traction motor because of its basic ruggedness, low cost, and high efficiency. As one can see in Figure 1.1, the induction motor traction drive has been continually evolving through a succession of programs spanning the past fifteen years. VPT marketed an induction motor-based traction drive system, the EV2000, which proved to be a reliable, high performance system that was used in a wide range of vehicles. The EV2000 drives evolved from the Modular Electric Vehicle Program (MEVP) and has been used in vehicles ranging in size from 3,000 lb. autos and utility vans, to 32,000 lb. city transit buses. Vehicles powered by the EV2000 induction motor powertrain have accumulated over 2 million miles of service. The EV2000 induction motor system represents 1993 state-of-the-art technology, and evolved from earlier induction motor programs that drove induction motor speeds up to 15,000 rpm to reduce the motor size and cost. It was recognized that the improvements in power density and motor cost sought in the PNGV program could only be achieved through increases in motor speed. Esson’s Rule for motor power clearly states that the power obtainable from a given motor design is the product of motor speed and volume. In order to meet the CARAT Program objectives, the maximum speed goal of the induction motor designed in this Program was increased from 15,000 rpm to 20,000 rpm while maintaining the efficiency and durability demonstrated by lower speed designs done in

  19. Traction curves for the decohesion of covalent crystals

    Enrique, Raúl A.; Van der Ven, Anton


    We study, by first principles, the energy versus separation curves for the cleavage of a family of covalent crystals with the diamond and zincblende structure. We find that there is universality in the curves for different materials which is chemistry independent but specific to the geometry of the particular cleavage plane. Since these curves do not strictly follow the universal binding energy relationship (UBER), we present a derivation of an extension to this relationship that includes non-linear force terms. This extended form of UBER allows for a flexible and practical mathematical description of decohesion curves that can be applied to the quantification of cohesive zone models.

  20. 3-Dimensional modelling of chick embryo eye development and growth using high resolution magnetic resonance imaging.

    Goodall, Nicola; Kisiswa, Lilian; Prashar, Ankush; Faulkner, Stuart; Tokarczuk, Paweł; Singh, Krish; Erichsen, Jonathan T; Guggenheim, Jez; Halfter, Willi; Wride, Michael A


    Magnetic resonance imaging (MRI) is a powerful tool for generating 3-dimensional structural and functional image data. MRI has already proven valuable in creating atlases of mouse and quail development. Here, we have exploited high resolution MRI to determine the parameters necessary to acquire images of the chick embryo eye. Using a 9.4 Tesla (400 MHz) high field ultra-shielded and refrigerated magnet (Bruker), MRI was carried out on paraformaldehyde-fixed chick embryos or heads at E4, E6, E8, and E10. Image data were processed using established and custom packages (MRICro, ImageJ, ParaVision, Bruker and mri3dX). Voxel dimensions ranged from 62.5 microm to 117.2 microm. We subsequently used the images obtained from the MRI data in order to make precise measurements of chick embryo eye surface area, volume and axial length from E4 to E10. MRI was validated for accurate sizing of ocular tissue features by direct comparison with previously published literature. Furthermore, we demonstrate the utility of high resolution MRI for making accurate measurements of morphological changes due to experimental manipulation of chick eye development, thereby facilitating a better understanding of the effects on chick embryo eye development and growth of such manipulations. Chondroitin sulphate or heparin were microinjected into the vitreous cavity of the right eyes of each of 3 embryos at E5. At E10, embryos were fixed and various eye parameters (volume, surface area, axial length and equatorial diameter) were determined using MRI and normalised with respect to the un-injected left eyes. Statistically significant alterations in eye volume (p < 0.05; increases with chondroitin sulphate and decreases with heparin) and changes in vitreous homogeneity were observed in embryos following microinjection of glycosaminoglycans. Furthermore, in the heparin-injected eyes, significant disturbances at the vitreo-retinal boundary were observed as well as retinal folding and detachment

  1. Human embryonic growth and development of the cerebellum using 3-dimensional ultrasound and virtual reality.

    Rousian, M; Groenenberg, I A L; Hop, W C; Koning, A H J; van der Spek, P J; Exalto, N; Steegers, E A P


    The aim of our study was to evaluate the first trimester cerebellar growth and development using 2 different measuring techniques: 3-dimensional (3D) and virtual reality (VR) ultrasound visualization. The cerebellum measurements were related to gestational age (GA) and crown-rump length (CRL). Finally, the reproducibility of both the methods was tested. In a prospective cohort study, we collected 630 first trimester, serially obtained, 3D ultrasound scans of 112 uncomplicated pregnancies between 7 + 0 and 12 + 6 weeks of GA. Only scans with high-quality images of the fossa posterior were selected for the analysis. Measurements were performed offline in the coronal plane using 3D (4D view) and VR (V-Scope) software. The VR enables the observer to use all available dimensions in a data set by visualizing the volume as a "hologram." Total cerebellar diameter, left, and right hemispheric diameter, and thickness were measured using both the techniques. All measurements were performed 3 times and means were used in repeated measurements analysis. After exclusion criteria were applied 177 (28%) 3D data sets were available for further analysis. The median GA was 10 + 0 weeks and the median CRL was 31.4 mm (range: 5.2-79.0 mm). The cerebellar parameters could be measured from 7 gestational weeks onward. The total cerebellar diameter increased from 2.2 mm at 7 weeks of GA to 13.9 mm at 12 weeks of GA using VR and from 2.2 to 13.8 mm using 3D ultrasound. The reproducibility, established in a subset of 35 data sets, resulted in intraclass correlation coefficient values ≥0.98. It can be concluded that cerebellar measurements performed by the 2 methods proved to be reproducible and comparable with each other. However, VR-using all three dimensions-provides a superior method for the visualization of the cerebellum. The constructed reference values can be used to study normal and abnormal cerebellar growth and development.

  2. IOL tilt and decentration estimation from 3 dimensional reconstruction of OCT image.

    Xiaogang Wang

    Full Text Available PURPOSE: To evaluate intraocular lens (IOL tilt and decentration by anterior segment optical coherence tomography (AS-OCT using 3-dimensional (3D reconstruction method. DESIGN: Prospective observational case series. PARTICIPANTS: Thirty-nine patients (39 eyes were included. METHODS: The IOL positions of all eyes were examined by AS-OCT. Images were obtained in 4 axes (0-180 degrees, 45-225 degrees, 90-270 degrees, and 135-315 degrees using the quadrant-scan model. The cross-sectional images were analyzed with MATLAB software. MAIN OUTCOME MEASURES: The angle (θ between the reference pupillary plane and the IOL plane, the distances between the center points of the pupil circle and the IOL on the x-axis (dx and y-axis (dy and the spatial distance (ds were calculated after 3D-reconstruction. RESULTS: The mean angle (θ between the pupillary plane and the IOL plane was 2.94±0.99 degrees. The mean IOL decentration of dx and dy was 0.32±0.26 mm and 0.40±0.27 mm, respectively. The ds of the IOL decentration was 0.56±0.31 mm. There was no significant correlation between the ocular residual astigmatism (ORA and the tilted angle or the decentration distance. There was a significant correlation between the ORA and total astigmatism (r = 0.742, P<0.001. There was no significant correlation between the postoperative best corrected visual acuity (BCVA and the ORA (r = 0.156; P = 0.344, total astigmatism (r = 0.012; P = 0.942, tilted angle (θ; r = 0.172; P = 0.295 or decentration distance (dx: r = 0.191, P = 0.244; dy: r = 0.253, P = 0.121; ds: r = 0.298, P = 0.065. CONCLUSIONS: AS-OCT can be used as an alternative for the analysis of IOL tilt and decentration using 3D-reconstruction.

  3. New Technique for Developing a Proton Range Compensator With Use of a 3-Dimensional Printer

    Ju, Sang Gyu, E-mail: [Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Kim, Min Kyu; Hong, Chae-Seon; Kim, Jin Sung; Han, Youngyih; Choi, Doo Ho [Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Shin, Dongho; Lee, Se Byeong [Proton Therapy Center, National Cancer Center, Gyeonggi-do (Korea, Republic of)


    Purpose: A new system for manufacturing a proton range compensator (RC) was developed by using a 3-dimensional printer (3DP). The physical accuracy and dosimetric characteristics of the new RC manufactured by 3DP (RC{sub 3}DP) were compared with those of a conventional RC (RC{sub C}MM) manufactured by a computerized milling machine (CMM). Methods and Materials: An RC for brain tumor treatment with a scattered proton beam was calculated with a treatment planning system, and the resulting data were converted into a new format for 3DP using in-house software. The RC{sub 3}DP was printed with ultraviolet curable acrylic plastic, and an RC{sub C}MM was milled into polymethylmethacrylate using a CMM. The inner shape of both RCs was scanned by using a 3D scanner and compared with TPS data by applying composite analysis (CA; with 1-mm depth difference and 1 mm distance-to-agreement criteria) to verify their geometric accuracy. The position and distal penumbra of distal dose falloff at the central axis and field width of the dose profile at the midline depth of spread-out Bragg peak were measured for the 2 RCs to evaluate their dosimetric characteristics. Both RCs were imaged on a computed tomography scanner to evaluate uniformity of internal density. The manufacturing times for both RCs were compared to evaluate the production efficiency. Results: The pass rates for the CA test were 99.5% and 92.5% for RC{sub 3}DP and RC{sub C}MM, respectively. There was no significant difference in dosimetric characteristics and uniformity of internal density between the 2 RCs. The net fabrication times of RC{sub 3}DP and RC{sub C}MM were about 18 and 3 hours, respectively. Conclusions: The physical accuracy and dosimetric characteristics of RC{sub 3}DP were comparable with those of the conventional RC{sub C}MM, and significant system minimization was provided.

  4. Long-Life, Oil-Free, Light-Weight, Multi-Roller Traction Drives for Planetary Vehicle Surface Exploration Project

    National Aeronautics and Space Administration — A multi-roller "oil free" traction drive is under development for use on vehicles used in hostile environments like those that will be encountered on planetary...

  5. Long-Life, Oil-Free Polymeric, Multi-Roller Traction Drives for Planetary Vehicle Surface Exploration Project

    National Aeronautics and Space Administration — Multi-roller traction drives have several advantages relative to geared units for aerospace and commercial drive applications. Among these are zero backlash, low...

  6. Novel Material to Quantify Sharpness and Traction of Vitreous Cutters

    Nazafarin Honarpisheh


    Full Text Available There is no available method for evaluating cutting quality of vitreotomes. The available methods of assessment allow only indirect judgment of their quality and are difficult to apply in clinical practice. We propose using a collagen film with maximum thickness of 1-2 micron to test the sharpness of instruments under conditions resembling clinical ones. The collagen film is fixed by a special device, then place in physiological saline, and then cut under the operation microscope. It shows whether the cutting edges are sharp enough, and the collagen film is cut smoothly. We also use an Electroforce 3100 machine and Dynamic Mechanical Analysis software to quantify the vitreoretinal force applied to the retina during vitrectomy.


    O.O. Matusevych


    Full Text Available Purpose. The purpose of this paper is development of methodology for definition of a quality system of maintenance and repair (M and P power equipment of traction substations (TS of electrified railways operating under conditions of uncertainty based on expert information. Methodology. The basic tenets of the theory of fuzzy sets and marks, linguistic and interval estimates of experts were applied to solve this problem. Results. Analysis of the existing diversity of approaches to development of modern methods of improvement of M and P allows us to conclude that the improvement in the quality of the system is achieved by solving individual problems increase the operational reliability of power equipment of traction substations in the following main interrelated areas. There are technical, economic and organizational. The basis of the quality evaluation system is initial data and expertise developed version of the document formalized quality evaluation of electrical equipment of traction substations by experts. The choice of determining the level of Quality service system based on the marks, linguistic and interval estimates of experts, which are reflected in quantitative and / or qualitative form was done. The possible options for expert data presentation and their corresponding quantitative methods of calculating the integral index of quality improvement system maintenance and P of traction substations were described. The methodology and the method of assessing the quality of system maintenance and P of TS allows quickly respond to changing operating conditions of power equipment of traction substations, and to determine the most effective strategies for maintenance of electrical and P TS under conditions of uncertainty functioning distance electricity. Originality. The method of a systematic approach to improve the quality of the system maintenance and P of power equipment of traction substation under conditions of uncertainty based on expert

  8. Experimental Research of Harmonic Spectrum of Currents at Traction Drive with PMSM

    J. Novak


    Full Text Available The paper deals with the significant results of the experimental research of current harmonic spectrum of traction drive with permanent magnet synchronous motor. The experiments were done on a special workplace with a real traction drive for wheel vehicles. Current harmonic spectrum was analyzed by a specialized device on the base of central measuring station. The knowledge of current marked subharmonic components of stator winding is the most significant finding of experiments. The frequencies of these components are given by multiples of frequency of mechanical speeds. The subharmonic components also pass to input DC current of drive. This fact is important in particular from the point of view of legislative requirements to electromagnetic compatibility of drive with railway interlocking devices.


    GUZELBEY Ibrahim H.; KANBER Bahattin; AKPOLAT Abdullah


    In this study, the stress based finite element method is coupled with the boundary element method in two different ways. In the first one, the ordinary distribution matrix is used for coupling. In the second one, the stress traction equilibrium is used at the interface line of both regions as a new coupling process. This new coupling procedure is presented without a distribution matrix. Several case studies are solved for the validation of the developed coupling procedure. The results of case studies are compared with the distribution matrix coupling, displacement based finite element method, assumed stress finite element method, boundary element method, ANSYS and analytical results whenever possible. It is shown that the coupling of the stress traction equilibrium with assumed stress finite elements gives as accurate results as those by the distribution matrix coupling.

  10. Study on Low-Temperature Traction Behavior of a Space Lubricating Oil No. 4116

    Wang Yanshuang; Cheng Junwei; Cai Yujun


    The traction behavior of space lubricating oil No. 4116 was measured and analyzed at various oil inlet tempera-tures below 0℃and various rolling speeds under normal loads by a test rig simulating the operating conditions of space bearings. A traction coefifcient calculation model was presented. The rheological property and rheological parameters of the lubricant at a low oil inlet temperature were analyzed based on the Tevaarwerk-Johnson model. The results showed that the lubricating oil No. 4116 was sensitive to the rolling speed and had lower sensitivity to the normal load. This lubricating oil is more suitable for applications under high speed when it is used below 0℃. It behaves as an elastic-plastic lfuid operating below 0℃. Both the average limiting shear stress and the average elastic shear modulus have a negative correlation with the rolling speed and oil inlet temperature and have a positive correlation with the normal load.

  11. Analysis and Comparison of Modular Railway Power Conditioner for High-Speed Railway Traction System

    Xu, Qianming; Ma, Fujun; He, Zhixing


    With the rapid development of modern electrified railway, negative sequence current (NSC) minimization is one of the most important considerations in the high-speed railway traction system. In the past, many multiple or multilevel topologies with high compensation capacity have been introduced...... for railway power conditioner (RPC). This paper presents a simplified quantitative comparison of five previous modular RPC topologies for negative sequence compensation in V/V and SCOTT traction systems, aiming for an optimal selection of the compensators. Performance criteria such as transformer requirement......, voltage stress and current stress of power switch, numbers of the power switches and capacitor are derived by analytical methods. Moreover, the numerical comparison of operating controllers is completed for modular RPCs. In addition, power losses of five modular RPCs are obtained by theoretical analysis...

  12. Traction coefficient in a roller-inner ring EHD contact in a jet engine roller bearing

    Sottomayor, A. [INEGI-CETRIB, Faculdade de Engenharia da Universidade do Porto (Portugal); Campos, A. [INEGI-CETRIB, Faculdade de Engenharia da Universidade do Porto (Portugal); Seabra, J. [Dept. de Engenharia Mecanica e Gestao Industrial, Faculdade de Engenharia da Universidade do Porto (Portugal)


    A simplified non-newtonian EHD model developed previously is used for the analysis of a roller-inner ring contact in a jet engine roller bearing. The lubricant behaves according to the viscoelastic rheological model, with a Ree-Eyring fluid, and the lubricant parameters are function of the pressure, temperature and rolling speed. The traction coefficient results obtained with this model are compared with previous experimental results obtained in a twin-disk machine. Finally, the influence of the operating conditions (pressure, temperature, rolling speed and slide-to-roll ratio) and of the waviness of the contacting surfaces, on the traction coefficient inside the roller-inner ring contact, is analysed. (orig.)

  13. Dynamics and Stability of Blind Grasping of a 3-Dimensional Object under Non-holonomic Constraints

    Suguru Arimoto; Morio Yoshida; Ji-Hun Bae


    A mathematical model expressing the motion of a pair of multi-DOF robot fingers with hemi-spherical ends,grasping a 3-D rigid object with parallel flat surfaces, is derived, together with non-holonomic constraints. By referring to the fact that humans grasp an object in the form of precision prehension, dynamically and stably by opposable forces, between the thumb and another finger (index or middle finger), a simple control signal constructed from finger-thumb opposition is proposed, and shown to realize stable grasping in a dynamic sense without using object information or external sensing (this is called "blind grasp" in this paper). The stability of grasping with force/torque balance under non-holonomic constraints is analyzed on the basis of a new concept named "stability on a manifold". Preliminary simulation results are shown to verify the validity of the theoretical results.


    Rotsos, Tryfon; Sagoo, Mandeep; da Cruz, Lyndon; Andrews, Richard; Dowler, Jonathan


    Abstract Purpose: To report the effect of intravitreal anti VEGF injections (IVI) on visual acuity (VA) in eyes with choroidal neovascularisation (CNVM) and coexistent vitreomacular traction (VMT) or when VMT has developed during the course of treatment. Methods: Retrospective interventional case series of 7 eyes in 7 patients. VMT was monitored with serial optical coherence tomography scans. Results: The aetiology of the CNVM was wet age-related macular degeneration in 5 e...


    Himanshi Sharma


    Full Text Available Background: Cervical radiculopathy is a dysfunction of nerve root of the cervical spine where C6& C7 nerve roots are the most commonly affected. It encompasses important symptoms other than pain, such as paresthesia, numbness and muscle weakness in dermatomal or myotomal distribution of an affected nerve root. A multitude of physical therapy interventions have been proposed to be effective in the management of cervical radiculopathy, including mechanical cervical traction, manipulation, therapeutic exercises and TENS. Studies to find out the effectiveness of TENS versus Intermittent Cervical Traction among patients with Cervical Radiculopathy are sparse. Hence the present study was undertaken to find out and compare effectiveness of TENS versus Intermittent Cervical Traction a newer technique towards betterment in treatment of cervical radiculopathy patients. Methodology: 30 patients from Baroda association for the blind (Lions club of Baroda, Subhanpura & Sushrut Physiotherapy Clinic, Akota were chosen based on the inclusion and exclusion criteria. Group A comprised of 15 people with cervical radiculopathy were given TENS with Isometric neck exercises and active neck movements. Group B comprised of 15 people with cervical radiculopathy were given Intermittent Cervical Traction with Isometric neck exercise and active neck movements. VAS Scale & Neck Disability Index (NDI were used as outcome measures pre & post treatment. Results: The pre test evaluation showed that, there is no significant difference (P> 0.05 between the two groups for all the variables measured. The post-test evaluation of both groups showed a very high significance (P< 0.05 within the group for all the outcome measurements. A post-test comparison of measured variables, between the groups showed that the Group A demonstrated a statistically significant (P< 0.05 reduction in pain and Neck Disability Index. Conclusion: From the above study concluded that TENS was more effective

  16. Radiographic evaluation of the use of transverse traction device in vertebral arthrodesis for degenerative diseases

    Edgar Takao Utino; João Paulo Machado Bergamaschi; Luciano Antonio Nassar Pellegrino; Ricardo Shigueaki Galhego Umeta; Maria Fernanda Silber Caffaro; Robert Meves; Osmar Avanzi


    OBJECTIVE: Perform radiographic analysis of the use of Transverse Traction Device (DTT) with respect to fusion rate in patients submitted to vertebral arthrodesis for degenerative lumbar diseases. METHODS: We selected x-ray images on anteroposterior, lateral and oblique views and with maximum flexion and extension dynamics of 23 patients submitted to posterolateral arthrodesis of the lumbar spine with a minimum follow-up period of six months. The images were evaluated and classified by the ...

  17. New Configuration of Traction Converter with Medium-Frequency Transformer: Primary Part

    Vojtech Blahnik


    Full Text Available This paper deals with new configuration of the traction converter with medium-frequency transformer intended for ac trolley wire fed locomotives. It is concerned to the primary serially connected single-phase voltage-source active rectifiers, which are directly connected to the trolley wire. This contribution presents the proposed control of the primary active rectifiers, simulation and experimental results of designed low-voltage laboratory prototype of converter of rated power of 12kW.

  18. Increases in COX II mRNA in the rat spinal cord induced by cauda equina traction.

    Hirabayashi, Kiyoko; Komagata, Masashi; Yamada, Jinzo; Isshiki, Atsushi; Watanabe, Yasuo


    This article investigated the time response of COX II induction by traction of the cauda equina assessed by a quantified RT-PCR method. Under deep GOI anesthesia, male Wistar rats were fixed in the prone position and a laminectomy of the dorsal part of the first and second sacral vertebrae was performed. Following, COX II-mRNA levels in the cervical, thoracic, lumbar, sacral, and caudal segments were measured at 2, 4, 6, and 24 h after traction by a quantified RT-PCR method. After cauda equina traction, significant levels of COX II mRNA were detected in all segments of the spinal cord examined. Maximum levels in each segment were determined 4 h after traction of the cauda equina. Particularly in the sacrocaudal segments significantly higher levels of COX II mRNA were measured 24 h after traction. These results indicate that significant induction of spinal COX II mRNA was caused by cauda equina traction and that such induction plays a regulatory role in the nociceptive pain pathway.

  19. Simultaneous Application of Fibrous Piezoresistive Sensors for Compression and Traction Detection in Glass Laminate Composites

    Nauman, Saad; Cristian, Irina; Koncar, Vladan


    This article describes further development of a novel Non Destructive Evaluation (NDE) approach described in one of our previous papers. Here these sensors have been used for the first time as a Piecewise Continuous System (PCS), which means that they are not only capable of following the deformation pattern but can also detect distinctive fracture events. In order to characterize the simultaneous compression and traction response of these sensors, multilayer glass laminate composite samples were prepared for 3-point bending tests. The laminate sample consisted of five layers of plain woven glass fabrics placed one over another. The sensors were placed at two strategic locations during the lay-up process so as to follow traction and compression separately. The reinforcements were then impregnated in epoxy resin and later subjected to 3-point bending tests. An appropriate data treatment and recording device has also been developed and used for simultaneous data acquisition from the two sensors. The results obtained, under standard testing conditions have shown that our textile fibrous sensors can not only be used for simultaneous detection of compression and traction in composite parts for on-line structural health monitoring but their sensitivity and carefully chosen location inside the composite ensures that each fracture event is indicated in real time by the output signal of the sensor. PMID:22163707

  20. Traction Converting Substation from Viewpoint of Feeding Interlocking Plant at Czech Railwayes

    Radovan Dolecek


    Full Text Available This paper presents analyses current and voltage harmonic in traction converting substation 3 kV. It researches their rise and influence to three-phase cable line 6 kV, 50 Hz that is used for feeding interlocking plant. Processing of this task is arisen from requirement practice for line Pěčky - Poříčany - Rostoklaty where happened to adverse ratio in particular transmission line of feeding system. It is meant especially about backward influence traction substation rectifier Pečky to three - phase cable line 6 kV, 50 Hz. At the determinate lenght of the cable line, when resonace frequency of circuit transformer 22 kV/6 kV and the cable line 6 kV, 50 Hz is approached frequency 550 Hz and 650 Hz (i.e. 11 and 13 harmonic are happened to socalled "annulations input reactance of this circuit". That is caused by the leakage of current resonace frequency from traction converting substation to cable line. That proceduces additional losses and deformation waveform of voltage too. This deformation can be reflected on how interlocking plant is working. 

  1. The evaluation of upper leg traction in lateral position for pediatric caudal block

    Mahin Seyedhejazi


    Full Text Available Purpose: A well-functioning caudal block is an excellent adjunct to general anesthesia, but misplaced injection results in poor analgesia as well as possibility of serious morbidity. Therefore, the purpose of this study was to evaluate the effectiveness of leg traction on success rate of caudal block in lateral position in children. Methods: Two hundred children, age 2 months to 6 years, ASA I and II, who underwent lower abdominal surgeries were randomized in prospective controlled clinical trial study in two groups. After induction of General anesthesia, the caudal block was performed in the lateral position with upper leg traction (L-T- or with the standard position (S-P (leg flexed 90΀. Hemodynamicchanges, movement of lower extremity in response to surgical stimulus were evaluated. Results: There was no significant difference in caudal block′s success rate between two groups at first attempt (P=0.25. In group (S-P the procedure was successful in 60% of cases at first attempt, 25% at second,10% at third attempt and 5% failure of caudal block, whereas in the first group it was 75%, 20%, 1% and 4% of cases respectively. There were no significant differences in heart rate and blood pressure changes between two groups (P>0.05. Conclusion: The success rate of pediatric caudal block in upper leg traction did not differ from that of the standard position.

  2. The nanoscale architecture of force-bearing focal adhesions.

    van Hoorn, Hedde; Harkes, Rolf; Spiesz, Ewa M; Storm, Cornelis; van Noort, Danny; Ladoux, Benoit; Schmidt, Thomas


    The combination of micropillar array technology to measure cellular traction forces with super-resolution imaging allowed us to obtain cellular traction force maps and simultaneously zoom in on individual focal adhesions with single-molecule accuracy. We achieved a force detection precision of 500 pN simultaneously with a mean single-molecule localization precision of 30 nm. Key to the achievement was a two-step etching process that provided an integrated spacer next to the micropillar array that permitted stable and reproducible observation of cells on micropillars within the short working distance of a high-magnification, high numerical aperture objective. In turn, we used the technology to characterize the super-resolved structure of focal adhesions during force exertion. Live-cell imaging on MCF-7 cells demonstrated the applicability of the inverted configuration of the micropillar arrays to dynamics measurements. Forces emanated from a molecular base that was localized on top of the micropillars. What appeared as a single adhesion in conventional microscopy were in fact multiple elongated adhesions emanating from only a small fraction of the adhesion on the micropillar surface. Focal adhesions were elongated in the direction of local cellular force exertion with structural features of 100-280 nm in 3T3 Fibroblasts and MCF-7 cells. The combined measure of nanoscale architecture and force exerted shows a high level of stress accumulation at a single site of adhesion.

  3. Editorial Commentary: Single-Image Slice Magnetic Resonance Imaging Assessments Do Not Predict 3-Dimensional Muscle Volume.

    Brand, Jefferson C


    No single-image magnetic resonance imaging (MRI) assessment-Goutallier classification, Fuchs classification, or cross-sectional area-is predictive of whole-muscle volume or fatty atrophy of the supraspinatus or infraspinatus. Rather, 3-dimensional MRI measurement of whole-muscle volume and fat-free muscle volume is required and is associated with shoulder strength, which is clinically relevant. Three-dimensional MRI may represent a new gold standard for assessment of the rotator cuff musculature using imaging and may help to predict the feasibility of repair of a rotator cuff tear as well as the postoperative outcome. Unfortunately, 3-dimensional MRI assessment of muscle volume is labor intensive and is not widely available for clinical use.

  4. Diagnosis of mitral valve cleft using real-time 3-dimensional echocardiography

    Zhou, Aiyun; Chen, Li; Zhang, Cheng; Zhang, Yan; Xu, Pan


    Background Mitral valve cleft (MVC) is the most common cause of congenital mitral insufficiency, and MVC may occur alone or in association with other congenital heart lesions. Direct suture and valvuloplasty are the major and effective treatments for mitral regurgitation (MR) caused by MVC. Therefore, it is important to determine the location and magnitude of the pathological damage due to MVC when selecting a surgical procedure for treatment. This study explored the application value of transthoracic real-time 3-dimensional (3D) echocardiography (RT-3DE) in the diagnosis of MVC. Methods From October 2012 to June 2016, 19 consecutive patients with MVC diagnosed by 2-dimensional (2D) echocardiography in our hospital were selected for this study. Full-volume RT-3DE was performed on all patients. The 3D-imaging data were cropped and rotated in 3 views (horizontal, sagittal, and coronal) with 6 directions to observe the position and shape of the MVC and the spatial position between the cleft and its surrounding structures. The maximum longitudinal diameter and the maximum width of the cleft were measured. The origin of the mitral regurgitant jet and the severity of MR were evaluated, and these RT-3DE data were compared with the intraoperative findings. Results Of the 19 patients studied, 4 patients had isolated cleft mitral valve, and cleft mitral valves combined with other congenital heart lesions were detected in 15 patients. The clefts of 6 patients were located in the A2 segment, the clefts of 4 patients were located in the A1 segment, the clefts of 4 patients were located in the A3 segment, the clefts of 4 patients were located in the A2–A3 segment, and the cleft of 1 patient was located in the P2 segment. Regarding the shape of the cleft, 13 patients had V-shaped clefts, and the others had C- or S-shaped clefts. The severity of the MR at presentation was mild in 2 patients, moderate in 9 and severe in 8. Two of the patients with mild MR did not undergo surgery

  5. Intelligent Layout Method of the Powerhouse for Tank & Armored Vehicles Based on 3-Dimensional Rectangular Packing Theory

    WANG Yan-long; MAO Ming; LU Yi-ping; BIE Jie-min


    Probes into a new and effective method in arranging the powerhouses of tank & armored vehicles. Theory and method of 3-dimensional rectangular packing are adapted to arrange effectively almost all the systems and components in the powerhouse of the vehicle, thus the study can be regarded as an attempt for the theory's engineering applications in the field of tank & armored vehicle design. It is proved that most parts of the solutions attained are reasonable, and some of the solutions are innovative.

  6. Study on the stability and 3-dimensional character for natural convection in a rectangular cavity heated from below


    Natural convection of air is numerically simulated in a 3-dimensional rectangular cavity heated from below using SIMPLE algorithm with a QUICK scheme.The results suggest that when all lateral walls are adiabatic,the fluid rolls occur along the long axis.When the Rayleigh number is smaller,the flow is of 2-dimensional character,and the rolls shapes are similar.The average Nusselt numbers in the central part of the cavity are similar.The average Nusselt numbers in the part near by the cavity are different.According to the comparison of 3-dimensional results with 2-dimensional results,the flow patterns and heat transfer in the central part of the cavity can be assumed as a 2-dimensional flow,While those in the part near by the cavity can not.With increasing Rayleigh number,the flow is 3-dimensional characteristic.The 3-dimensional result accords with the experimental result.When all lateral walls are adiabatic,the ten rolls occur along the long axis.But when lateral walls are heated or cooled,the rolls disappear along the long axis and two rolls occur along the short axis.The rotation direction of the rolls is reversed.When Rayleigh number is over some critical value,flow and heat transfer will be asymmetry,indicating unsteady oscillation occurs.By nonlinear analyses,it is shown that with increasing Rayleigh number,flow and heat transfer will change from steady state to unsteady state through HOPF bifurcation,and transition to chaos will occur through multi-periodical oscillation.

  7. Targeting FAK Radiosensitizes 3-Dimensional Grown Human HNSCC Cells Through Reduced Akt1 and MEK1/2 Signaling

    Hehlgans, Stephanie [OncoRay-National Center for Radiation Research in Oncology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden (Germany); Department of Radiotherapy and Oncology, University of Frankfurt, Frankfurt am Main (Germany); Institute of Radiopharmacy, Helmholtz Center Dresden-Rossendorf, Dresden (Germany); Eke, Iris [OncoRay-National Center for Radiation Research in Oncology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden (Germany); Cordes, Nils, E-mail: [OncoRay-National Center for Radiation Research in Oncology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden (Germany); Institute of Radiopharmacy, Helmholtz Center Dresden-Rossendorf, Dresden (Germany); Department of Radiation Oncology, University Hospital and Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden (Germany)


    Purpose: Focal adhesion kinase (FAK), a main regulator of integrin signaling and cell migration, is frequently overexpressed and hyperphosphorylated in human head-and-neck squamous cell carcinoma (HNSCC). We have previously shown that pharmacologic FAK inhibition leads to radiosensitization of 3-dimensionally grown HNSCC cell lines. To further evaluate the role of FAK in radioresistance and as a potential cancer target, we examined FAK and FAK downstream signaling in HNSCC cell lines grown in more physiologic extracellular matrix-based 3-dimensional cell cultures. Methods and Materials: Seven HNSCC cell lines were grown in 3-dimensional extracellular matrix and the clonogenic radiation survival, expression, and phosphorylation of FAK, paxillin, Akt1, extracellular signal-regulated kinase (ERK)1/2, and MEK1/2 were analyzed after siRNA-mediated knockdown of FAK, Akt1, MEK1, FAK+Akt1, or FAK+MEK1 compared with controls or stable overexpression of FAK. The role of MEK1/2 for clonogenic survival and signaling was investigated using the MEK inhibitor U0126 with or without irradiation. Results: FAK knockdown moderately or significantly enhanced the cellular radiosensitivity of 3-dimensionally grown HNSCC cells. The FAK downstream targets paxillin, Akt1, and ERK1/2 were substantially dephosphorylated under FAK depletion. FAK overexpression, in contrast, increased radiation survival and paxillin, Akt1, and ERK1/2 phosphorylation. The degree of radiosensitization upon Akt1, ERK1/2, or MEK1 depletion or U0126 was superimposable to FAK knockdown. Combination knockdown conditions (ie, Akt1/FAK, MEK1/FAK, or U0126/FAK) failed to provide additional radiosensitization. Conclusions: Our data provide further evidence for FAK as important determinant of radiation survival, which acts in the same signaling axis as Akt1 and ERK1/2. These data strongly support our hypothesis that FAK is a relevant molecular target for HNSCC radiotherapy.

  8. Unified description of magic numbers of metal clusters in terms of the 3-dimensional q-deformed harmonic oscillator

    Bonatsos, Dennis; Lenis, D; Raychev, P P; Roussev, R P; Terziev, P A


    Magic numbers predicted by a 3-dimensional q-deformed harmonic oscillator with Uq(3)>SOq(3) symmetry are compared to experimental data for atomic clusters of alkali metals (Li, Na, K, Rb, Cs), noble metals (Cu, Ag, Au), divalent metals (Zn, Cd), and trivalent metals (Al, In), as well as to theoretical predictions of jellium models, Woods-Saxon and wine bottle potentials, and to the classification scheme using the 3n+l pseudo quantum number. In alkali metal clusters and noble metal clusters the 3-dimensional q-deformed harmonic oscillator correctly predicts all experimentally observed magic numbers up to 1500 (which is the expected limit of validity for theories based on the filling of electronic shells), while in addition it gives satisfactory results for the magic numbers of clusters of divalent metals and trivalent metals, thus indicating that Uq(3), which is a nonlinear extension of the U(3) symmetry of the spherical (3-dimensional isotropic) harmonic oscillator, is a good candidate for being the symmetry ...

  9. Study on the Method of Traction Motor Load Simulation on Railway Vehicles%轨道车辆牵引电机负载模拟方法的研究

    孙湖; 陆峰; 徐龙; 杨中平


    在分析了轨道车辆运行过程中牵引电机与传动齿轮、轮对以及轮轨之间力的作用关系的基础上,分别从力和功率的角度建立牵引电机——轮对传动机构的数学模型,得到牵引电机实际负载转矩的表达式;将牵引电机的实际负载等效为阻力负载和惯性负载两个部分,提出了用负载电机转矩模拟阻力负载,用飞轮或负载电机转矩模拟惯性负载的方法;结合CRH2型动车组的实车参数及牵引特性曲线,对电机负载的推导结果进行了验证;结果表明车辆加速性能与实际性能曲线一致,此方法能够准确模拟实车牵引电机负载.%Based on the analysis of force interaction between traction motor, transmission gear, wheelset and wheel-rail during the operation of railway vehicles, established the mathematical model of motor-wheelset traction system, respectively from the perspective of mechanics and power, drawing out the expression of the actual load of traction motor; and equivalented the actual load to two parts as resistance load and inertial load, and put forwards a method, that is to simulate the resistance load with torque of load motor, inertia load with flywheel or load motor torque. Consulting with the actual parameters and the traction performance curve of CRH2 EMUs, it authenticates and simulates the derivation of the motor load results. The simulation results show the agreement of performance of simulated vehicles and the actual performance curve. It indicates that the method can exactly simulate the real vehicle traction motor load.


    O. O. Matusevych


    Full Text Available Purpose. The study provides the methods and models development of reducing damages of traction energy systems (TES at electrified railways of Ukraine. Definition the indicator of preventing damage evaluation TES at electrified railways is necessary. Paper is aimed to search the modern methods and approaches to improve the system of TES monitoring, diagnosis and maintenance. Methodology. To achieve this purpose a study of foreign experience and publications that focus on problem-solving quality of TES using a linguistic approach based on the theory of fuzzy multiple numbers and linguistic variable were done. Findings. In result of research an algorithm to reduce TPS damages which operates under uncertainty was developed. It is found that the solution of this problem is possible by timely detection of actual technical condition of equipment in terms of quality maintenance, diagnostics and update resource of electrical equipment traction substations (TS power supply TES. The study examined the fuzzy inference scheme, which is based on the use of mechanisms to minimize the area of decision-making. It contributes not only to structural identification in the process of developing a database, but also can significantly improve the efficiency of finding the parameters of fuzzy model, which in turn reduces the efforts that are necessary for the analysis and the design of effective control systems maintenance and repair (M and R TES. Originality. For the first time the algorithm of reduction the damage of traction energy system of electrified railways of Ukraine was offered. The mathematical model of reduction the damage calculation of TES from TP power equipment failures by improving system maintenance (M and P was developed. Firstly evaluation index was proposed to prevent the damage of traction energy system. Practical value. The article describes the fuzzy inference scheme, which is based on the use of the mechanism to minimize the area of decision

  11. Application of optical coherence tomography (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells

    Thrane, Lars; Jørgensen, Thomas Martini; Jørgensen, Mikkel;


    The 3-dimensional imaging of complete polymer solar cells prepared by roll-to-roll coating was carried out using high-resolution 1322 nm optical coherence tomography (OCT) system. We found it possible to image the 3-dimensional structure of the entire solar cell that comprises UV-barrier, barrier...

  12. In vivo DTI longitudinal measurements of acute sciatic nerve traction injury and the association with pathological and functional changes

    Li, Xinchun [Department of Radiology, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiangxi Road, Guangzhou 510120 (China); Chen, Jingcong [Department of Radiology, The Center People Hospital of Huizhou, Huizhou 516001 (China); Hong, Goubin [Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000 (China); Sun, Congpeng; Wu, Xiaomen [Department of Radiology, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiangxi Road, Guangzhou 510120 (China); Peng, Matthew Jianqiao, E-mail: [Department of Joint Surgery, The First Affiliated Hospital of Guangzhou Medical University, Orthopedic Implantation Key Lab of Guangdong Province, 151 Yanjiangxi Road, Guangzhou 510120 (China); Zeng, Guangqiao, E-mail: [State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiangxi Road, Guangzhou 510120 (China)


    Objective: To explore the feasibility of longitudinally measuring acute traction injury to the sciatic nerve using 1.5 T clinical MRI scanner of diffusion tensor imaging (DTI) and to analyze the associations of the measurements [regarding fractional anisotropy (FA), apparent diffusion coefficient (ADC), eigenvalue (λ{sub ||} and λ{sub ⊥})] with limb function and pathology. Materials and methods: Acute traction injuries to the sciatic nerve were created in the right hind limbs of 32 New Zealand white rabbits, the left hind limbs were chosen as sham operation nerves. MRI scans were performed at intervals from pre-operation through 8 weeks post-operation follow up. Scanning sequences included T2WI, STIR, and single shot spin echo DTI with single shot EPI acquisition (SE-DTI-SSEPI). Parameters of FA, ADC, axial diffusivity (λ{sub ||}) and radial diffusivity (λ{sub ⊥}) were then calculated from the DTI. The limb functions and pathologic changes were evaluated and compared. Results: Diffusion Tensor Tractography (DTT) only revealed the proximal portion of the injured nerves 1–3 days after traction injury but did not reveal the nerve of the distal and traction portions at all. Nerve fibers of the distal and traction portions were not revealed by DTT until after the 1st week. They were elongated gradually and recovered almost to the normal at 8th week. The value of FA and λ{sub ⊥}of the injured nerves, which varied in different portions, were significantly different between the traction injury nerves and the sham operation nerves, whereas the value of ADC and λ{sub ||} were not significantly different. The curve lines of FA value-time for the proximal, traction and distal portions of the injured nerve correlated well to the functional and pathological changes of the limb affected, while the DTI parameters did not change that much in the sham-operated nerves. Conclusions: DTI obtained on a 1.5 T clinical MRI scanner can demonstrate early abnormal changes

  13. Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells.

    Reffay, M; Parrini, M C; Cochet-Escartin, O; Ladoux, B; Buguin, A; Coscoy, S; Amblard, F; Camonis, J; Silberzan, P


    The leading front of a collectively migrating epithelium often destabilizes into multicellular migration fingers where a cell initially similar to the others becomes a leader cell while its neighbours do not alter. The determinants of these leader cells include mechanical and biochemical cues, often under the control of small GTPases. However, an accurate dynamic cartography of both mechanical and biochemical activities remains to be established. Here, by mapping the mechanical traction forces exerted on the surface by MDCK migration fingers, we show that these structures are mechanical global entities with the leader cells exerting a large traction force. Moreover, the spatial distribution of RhoA differential activity at the basal plane strikingly mirrors this force cartography. We propose that RhoA controls the development of these fingers through mechanical cues: the leader cell drags the structure and the peripheral pluricellular acto-myosin cable prevents the initiation of new leader cells.

  14. Mechanical Hybrid KERS Based on Toroidal Traction Drives: An Example of Smart Tribological Design to Improve Terrestrial Vehicle Performance

    Francesco Bottiglione


    Full Text Available We analyse in terms of efficiency and traction capabilities a recently patented traction drive, referred to as the double roller full-toroidal variator (DFTV. We compare its performance with the single roller full-toroidal variator (SFTV and the single roller half-toroidal variator (SHTV. Modeling of these variators involves challenging tribological issues; the traction and efficiency performances depend on tribological phenomena occurring at the interface between rollers and disks, where the lubricant undergoes very severe elastohydrodynamic lubrication regimes. Interestingly, the DFTV shows an improvement of the mechanical efficiency over a wide range of transmission ratios and in particular at the unit speed ratio as in such conditions in which the DFTV allows for zero-spin, thus strongly enhancing its traction capabilities. The very high mechanical efficiency and traction performances of the DFTV are exploited to investigate the performance of a flywheel-based Kinetic Energy Recovery System (KERS, where the efficiency of the variator plays an important role in determining the overall energy recovery performance. The energy boost capabilities and the round-trip efficiency are calculated for the three different variators considered in this study. The results suggest that the energy recovery potential of the mechanical KERS can be improved with a proper choice of the variator.

  15. 3-dimensional thermohydraulic analysis of KALIMER reactor pool during unprotected accidents

    Lee, Yong Bum; Hahn Do Hee


    During a normal reactor scram, the heat generation is reduced almost instantaneously while the coolant flow rate follows the pump coastdown. This mismatch between power and flow results in a situation where the core flow entering the hot pool is at a lower temperature than the temperature of the bulk pool sodium. This temperature difference leads to thermal stratification. Thermal stratification can occur in the hot pool region if the entering coolant is colder than the existing hot pool coolant and the flow momentum is not large enough to overcome the negative buoyancy force. Since the fluid of hot pool enters IHXs, the temperature distribution of hot pool can alter the overall system response. Hence, it is necessary to predict the pool coolant temperature distribution with sufficient accuracy to determine the inlet temperature conditions for the IHXs and its contribution to the net buoyancy head. Therefore, two-dimensional hot pool thermohydraulic model named HP2D has been developed. In this report code-to-code comparison analysis between HP2D and COMMIX-1AR/P has been performed in the case of steady-state and UTOP.

  16. Research on surface traction calibration method of drum test-bed system%汽车转鼓试验台表面牵引力标定方法研究

    李宁; 赵树朋; 牛博英; 刘丹


    为了确保转鼓试验台系统的精度,需要对其系统进行标定.标定的主要问题是如何对确定量进行测量,并通过何种调节手段,达到显示值与实际值之间的偏差符合精度要求的目的.汽车转鼓试验台转鼓主轴与转鼓电机主轴是重合的,转鼓通过电机主轴将其表面上牵引力传递给电机转子,依靠转子和定子的相互作用,牵引力将被传至与定子固定连接的电机外壳上.因此在电机外壳上安装测力传感器测量电机外壳切线方向上的力实现对转鼓试验台表面牵引力的测量.设计采用双向标定臂可以减小额外扭矩的影响,确保了汽车转鼓试验台表面牵引力的测试精度要求.%The drum test-bed system needs to be calibrated in order to ensure its accuracy, The main problem of calibration is how to measure the determination of quantity so that deviation between the display and actual values can meet the accuracy requirements by some adjustment means, Drum shaft of automobile chassis dynamometer is coincident with the drum motor shaft, the traction of drum surface is transmitted to the motor rotor through the motor shaft, Eventually the traction is transmitted to the motor casing connected with the stator relying on the rotor and stator interaction. Therefore the drum test bench surface traction can be measured from the motor casing tangential force using force sensor mounted on the motor casing. The design adopts bidirectional calibration arm, it can decrease the effect of extra torque to ensure the test precision of automobile chassis dynamometer surface traction

  17. Perfluorocarbon-perfused 23 gauge three-dimensional vitrectomy for complicated diabetic tractional retinal detachment

    Velez-Montoya, Raul; Guerrero-Naranjo, Jose Luis; Garcia-Aguirre, Gerardo; Morales-Cantón, Virgilio; Fromow-Guerra, Jans; Quiroz-Mercado, Hugo


    Background Perfluorocarbon liquid (PCL)-perfused vitrectomy has been shown in previous studies to be feasible, safe, and to have advantages in managing complicated cases of tractional retinal detachment. The present study had the objectives of describing the anatomical results and measuring surgical time and PCL consumption when combining PCL-perfused techniques with modern vitrectomy equipment. Methods A prospective, interventional consecutive case series was investigated. We enrolled patients with diabetic tractional retinal detachment, complicated by proliferative vitreoretinopathy and poor vision. A 23 gauge PCL-perfused vitrectomy was done with three-dimensional settings. During the procedure, we assessed the degree of surgical bleeding, visualization quality, and difficulty of membrane dissections. Visual acuity, intraocular pressure, and anatomical success were assessed at one and 3 months of follow-up. Results Twelve patients were enrolled in this study. There were no statistical significant changes in intraocular pressure and visual acuity throughout the follow-up period. Surgery was performed in a hemorrhage-free environment in almost all cases, with good visualization and low technical difficulty. The mean complete surgical time was 94.92 ± 25.03 minutes. The mean effective vitrectomy time was 22.50 ± 19.04 minutes and the mean PCL consumption was 25.08 ± 9.76 mL, with a speed of 1.11 mL/minute. Anatomical success was 67% at 3 months. Conclusion Although the technique proved to have some advantages in managing complicated cases of diabetic tractional retinal detachment, there was a high consumption of PCL. A redesign of the entire system is needed in order to decrease the amount of PCL needed for the technique. PMID:22267907

  18. The efficacy of lumbar traction in the management of patients with low back pain.

    Borman, Pinar; Keskin, Dilek; Bodur, Hatice


    The literature on the efficacy of traction in the treatment of low back pain (LBP) is conflicting. The aim of this study was to examine its efficacy in this disorder. Forty-two patients with at least 6 weeks of nonspecific LBP were selected. Demographic data were obtained. All patients completed the Oswestry disability index (ODI) to assess disability and the 10-cm visual analog scale (VAS) for evaluation of pain. Subjects were randomly assigned into group 1, receiving only standard physical therapy, or group 2, receiving standard physical therapy with conventional lumbar traction. Standard physical therapy consisted of local heat, ultrasound for the lumbar region, and an active exercise program, given for ten sessions in all. The subjects received instruction on correct posture and recommended therapeutic exercises. They were reevaluated at the end of treatment and at 3-month follow-up. The mean outcome measures were global improvement and satisfaction with the therapy, as well as disability by ODI and pain by VAS. There were no group differences in terms of demographic and baseline clinical characteristics. There was a significant reduction in pain intensity and disability at the end of treatment in both groups. There was complete or mild improvement in 47.6% of group 1 and 40% of group 2. The satisfaction rate with both treatments was more than 70% immediately after the therapies. During the 3-month period, the outcome measures except disability remained statistically stable, with no difference amongst groups. Disability was significantly reduced at follow-up in both groups. Of the patients, 51% continued with the recommended exercises and had significantly lower disability scores than those who did not continue with the exercises. Pain and global improvement were also better in this group, but the difference was not statistically significant. In conclusion, no specific effect of traction on standard physical therapy was observed in our study group. We suggest

  19. Comparison of Different Parallel Implementaions of the 2+1-Dimensional KPZ Model and the 3-Dimensional KMC Model

    Kelling, Jeffrey; Ferenc, Máté Nagy; Schulz, Henrik; Heinig, Karl-Heinz


    We show that efficient simulations of the Kardar-Parisi-Zhang interface growth in 2 + 1 dimensions and of the 3-dimensional Kinetic Monte Carlo of thermally activated diffusion can be realized both on GPUs and modern CPUs. In this article we present results of different implementations on GPUs using CUDA and OpenCL and also on CPUs using OpenCL and MPI. We investigate the runtime and scaling behavior on different architectures to find optimal solutions for solving current simulation problems in the field of statistical physics and materials science.

  20. Numerical study of certain 3-dimensional effects in a sectioned MHD generator channel with successive inclusion of electrodes

    Ovchinnikov, V.L.


    In a 3-dimensional statement, a study is made of the effect of finite sectioning, shapes of electrodes and heterogeneity of the plasma parameters on the characteristics of the diagonal MHD generator. It is indicated that increase in specific electrical conductance of the plasma at the insulator wall results in a monotonic decrease in the voltage idling. There is an optimal specific electrical conductance of plasma at the electrode wall in which the voltage idling is the maximum. The expediency is shown of making channels with external commutation. There is an optimal ratio between the lengths of the electrode and the insulator.

  1. System design of the traction power supply for the high-speed line Beijing - Tianjin

    Altmann, Martin; Fischer, Andreas; Tornow, Torsten [Siemens AG, Erlangen (Germany)


    The high-speed line Beijing - Tianjin connecting the Capital Beijing with the harbour city Tianjin is the first high-speed line in China dedicated only to passenger traffic and is operated at 300 km/h. The commercial service started in due time for the Olympic games in 2008. For the system design and a reliable traction power supply the simulation software Sitras {sup registered} Sidytrac was used. The program incorporates all modules necessary for the overall system design and relating detailed investigations. Measurements during system integration test validated the simulation results. (orig.)

  2. [Brain abscess following the use of skull traction with Gardner-Wells tongs].

    Soyer, J; Iborra, J P; Fargues, P; Pries, P; Clarac, J P


    Brain abscess after insertion of skull traction is a rare and serious complication. Its development is secondary to superficial infection. Adequate preventive measures have to be taken: proper sterile dressing and daily care. Signs of local irritation are not always synonymous with skull migration. When gradual loosening of the skull occurs, especially associated with superficial infection, the pins must not be tightened. The more appropriate management is to investigate for penetration of the inner cranial cave. When in doubt, repositioning the pins may be necessary, as well as establishing an aggressive treatment against cutaneous infection.

  3. On parameters determination of multi-port equivalent scheme for multi-winding traction transformers

    Sobczyk Tadeusz J.


    Full Text Available This paper aims to present a new equivalent scheme of multi-windings traction transformers, based on multiport purely inductive circuit. The mathematical background of this equivalent scheme is described. The determination of the different scheme elements is made through a finite-elements calculation of both main and leakage inductances, for the case of a four-winding transformer. A procedure is defined, which allows to estimate the values of these elements from some measurements on the transformer at no-load and short-circuit operations. A specific strategy of short-circuit tests is described, allowing to determine all parameters in a rather simple way.

  4. Halo Gravity Traction Is Associated with Reduced Bone Mineral Density of Patients with Severe Kyphoscoliosis

    Xiao Han; Weixiang Sun; Yong Qiu; Leilei Xu; Shifu Sha; Benlong Shi; Huang Yan; Zhen Liu; Zezhang Zhu


    Background. Halo gravity traction (HGT) is one of the most commonly used perioperative techniques for the treatment of severe kyphoscoliosis. This study was to explore the influence of HGT on the BMD of these patients. Methods. Patients with severe kyphoscoliosis treated by preoperative HGT for at least 2 months were included. Patients' BMD were assessed by dual-energy X-ray absorptiometry at lumbar spine (LS, L2–L4) and femur neck (FN) of the nondominant side. The weight and duration of trac...

  5. Electric traction motion power and energy supply : basics and practical experience

    Steimel, Andreas


    This book has evolved from the lecture series ""Elektrische Bahnen" (""Electric railways") which has been held at Ruhr-Universität Bochum since 1996. Its primary audience are students of electrical energy technologies, control engineering and mechanical engineering as well as young engineers of electrical engineering, especially in the fields of power electronics, in railway industry and in railway-operating companies. The book intends to convey mechanical fundamentals of electric railway propulsion, which includes rail-bound guidance, transmission of traction effort from wheel to rail under t

  6. Solitary SH waves in two-layered traction-free plates

    Djeran-Maigre, Irini; Kuznetsov, Sergey


    A solitary wave, resembling a soliton wave, is observed when analyzing the linear problem of polarized shear (SH) surface acoustic waves propagating in elastic orthotropic two-layered traction-free plates. The analysis is performed by applying a special complex formalism and the Modified Transfer Matrix (MTM) method. Conditions for the existence of solitary SH waves are obtained. Analytical expressions for the phase speed of the solitary wave are derived. To cite this article: I. Djeran-Maigre, S. Kuznetsov, C. R. Mecanique 336 (2008).

  7. 3-dimensional Simulation of an Air-lift Pump from Bubbly to Slug Flow

    Jo, Hongrae; Jo, Daeseong [Kyungpook National Univ, Daegu (Korea, Republic of)


    The air-lift pump has been used in various applications with its merit that it can pump up without any moving parts. E.g. coffee percolator, petroleum industry, suction dredge, OTEC i.e. ocean thermal energy conversion and so on. By the merit, it has high durability for high temperature water or vapor, and fluid-solid mixture like waste water, muddy water and crude, which cause problems when it's pumped up with general pumps. In this regard, the air-lift pump has been one of the most desirable technology. A typical air-lift pump configuration is illustrated in Figure 01. The principle of this pump is very simple. When air is injected from the injector at bottom of a submerged tube, i.e., air bubbles are suspended in the liquid, the average density of the mixture in the tube is less than that of the surrounding fluid in the reservoir. Then hydrostatic pressure over the length of the tube is decreased. This buoyancy force causes a pumping action. The comparison of the simulated results, experimental result, and theoretical result is been able by data shown as Figure 04. They have similar trends but they also have a little differences because there are some limits of simulating the flow regimes. At the different flow condition, different coefficients for friction factor or pressure drop should be used, but this simulation uses a laminar condition and the theoretical equations are valid only for slug regime where the air flow rate is lower than the other regimes. From these causes, the differences has arisen, and difference comes bigger as the air flow rate increases, i.e., becoming annular flow regime or churn flow regime.

  8. Shell tension forces propel Dictyostelium slugs forward.

    Rieu, Jean-Paul; Delanoë-Ayari, Hélène


    The Dictyostelium slug is an excellent model system for studying collective movements, as it is comprised of about 10(5) cells all moving together in the same direction. It still remains unclear how this movement occurs and what the physical mechanisms behind it are. By applying our recently developed 3D traction force microscopy, we propose a simple explanation for slug propulsion. Most of the forces are exerted by the sheath surrounding the slug. This secreted shell is under a rather uniform tension (around 50 mN m(-1)) and will give rise to a tissue under pressure. Finally, we propose that this pressure will naturally push the slug tip forwards if a gradient of shell mechanical properties takes place in the very anterior part of the raised tip.

  9. The effect of material composition of 3-dimensional graphene oxide and self-doped polyaniline nanocomposites on DNA analytical sensitivity.

    Yang, Tao; Chen, Huaiyin; Yang, Ruirui; Wang, Xinxing; Nan, Fuxin; Jiao, Kui


    Until now, morphology effects of 2-dimensional or 3-dimensional graphene nanocomposites and the effect of material composition on the biosensors have been rarely reported. In this paper, the various nanocomposites based on graphene oxide and self-doped polyaniline nanofibres for studying the effect of morphology and material composition on DNA sensitivity were directly reported. The isolation and dispersion of graphene oxide were realized via intercalated self-doped polyaniline and ultrasonication, where the ultrasonication prompts the aggregates of graphite oxide to break up and self-doped polyaniline to diffuse into the stacked graphene oxide. Significant electrochemical enhancement has been observed due to the existence of self-doped polyaniline, which bridges the defects for electron transfer and, in the mean time, increases the basal spacing between graphene oxide sheets. Different morphologies can result in different ssDNA surface density, which can further influence the hybridization efficiency. Compared with 2-dimensional graphene oxide, self-doped polyaniline and other morphologies of nanocomposites, 3-dimensional graphene oxide-self-doped polyaniline nanowalls exhibited the highest surface density and hybridization efficiency. Furthermore, the fabricated biosensors presented the broad detection range with the low detection limit due to the specific surface area, a large number of electroactive species, and open accessible space supported by nanowalls.

  10. Cleft posterior mitral valve leaflet in an adult with Turner syndrome diagnosed with the use of 3-dimensional transesophageal echocardiography.

    Negrea, Stefania Luminita; Alexandrescu, Clara; Sabatier, Michel; Dreyfus, Gilles D


    Turner syndrome is a monosomy (45,X karyotype) in which the prevalence of cardiovascular anomalies is high. However, this aspect of Turner syndrome has received little attention outside of the pediatric medical literature, and the entire spectrum of cardiovascular conditions in adults remains unknown. We present the case of a 34-year-old woman who had Turner syndrome. When she was a teenager, her native bicuspid aortic valve was replaced with a mechanical prosthesis. Fifteen years later, during preoperative examination for prosthesis-patient mismatch, severe mitral regurgitation was detected, and a congenital cleft in the posterior leaflet of the mitral valve was diagnosed with use of 3-dimensional transesophageal echocardiography. The patient underwent concurrent mitral valve repair and aortic valve replacement. To our knowledge, this is the first report of a cleft in the posterior mitral valve leaflet as a cardiovascular defect observed in Turner syndrome, and the first such instance to have been diagnosed with the use of 3-dimensional echocardiography.


    Singh Varun


    Full Text Available Background : Low back pain is one of the most prevalent condition . According to the American Association of Orthopaedic Surgeons about 80 percent of people will have at least one bout with back pain during their lifetime . Various treatments methods have been used like traction SLR , posterior to anterior mobilization etc, but no study was done to compare the effects of posterior to anterior mobilization and traction SLR technique in reducing pain and increasing neurodynamic mobility in patients of low back pain. Purpose of study : To find out the effectiveness of traction SLR and posterior to Anterior mobilization in decreasing pain and increasing neurodynamic mobility of low back pain patients. Method : 20 subjects were taken as per selection criteria which included both male and female between the age of 25 to 45 years. They were randomly divided into two groups, group A (n=10 subjects received traction SLR and group B (n=10 received posterior to anterior mobilization. Range Of Motion and VAS were taken as outcome measurement parameters. Result: Comparison was made between pre and post reading within group using related t – test and between groups by using unrelated t-test for statistical analysis. Result showed statistically significant improvement between pre and post intervention VAS score for both group A and B. Result showed a statistically significant improvement between pre and post intervention ROM in for both Group A and B. Result shows statistically non significant difference between Group A and B in ROM and VAS scores. Conclusion: Traction SLR and posterior to anterior mobilization are effective in improving ROM and pain in patients suffering from low back pain. However there was no statistically significant difference between Traction SLR and posterior to anterior mobilization in improving Pain and ROM in patients suffering from low back pain.

  12. [Use of local injections of tolperisone (midocalm) in combination with tractional therapy in the treatment of vertebral static syndrome].

    Zakharov, Ia Iu; Kutarev, R V; Shelkov, S N; Suslov, S A


    A randomized double-blind study of the efficacy of midocalm combined with tractional therapy has been carried out in 24 patients (indexed group) comparing to the tractional therapy without midocalm (the drug has been substituted with placebo) in 25 patients (comparison group). The effective number of injections was 3-6 in the indexed group and 7 in the comparison group. A quantitative assessment revealed that in the indexed group treatment efficacy was 1,56 times higher and the effect achieved sooner than in the comparison group.

  13. Concepts of electrical traction equipments for the operation without overhead cables; Konzepte elektrischer Antriebsausruestungen fuer Betrieb ohne Oberleitung

    Fassbinder, Stefan [Deutsches Kupferinstitut, Duesseldorf (Germany)


    High energy costs and complex operating conditions meet the development of unusual drive concepts for locomotives and trainsets. In several areas, the traction accumulator could play an important role. There exist railway lines, at which electrification cannot be considered at present. Innovative traction concepts already are implemented or in principle available for the operation of these railway lines. These concepts aim to take along affordable energy for diesel-hybrid vehicles or also for electric vehicles by storage and/or to utilize the fuel for the diesel engine better.


    A. A. Sulim


    Full Text Available At present a great attention is paid to increasing of energy efficiency at operated electrified urban transport. Perspective direction for increasing energy efficiency at that type of transport is the application of regenerative braking. For additional increasing of energy efficiency there were suggested the use of capacitive drive on tires of traction substation. One of the main task is the analysis of energy recovery application  with drive and without it.These analysis demonstrated that the calculation algorithms don’t allow in the full volume to carry out calculations of amount and cost of energy recovery without drive and with it. That is why we see the current interest to this topic. The purpose of work is to create methods of algorithms calculation for definite amount and cost of consumed, redundant and recovery energy of electrified urban transport due to definite regime of motion on wayside. There is algorithm developed, which allow to calculate amount and cost of consumed, redundant and recovery energy of electrified urban transport on wayside during the installation capacitive drive at traction substation. On the basis of developed algorithm for the definite regime of wagon motion of subway there were fulfilled the example of energy recovery amount and its cost calculation, among them with limited energy intensity drive, when there are 4 trains on wayside simultaneously.

  15. Traction-assisted colonic endoscopic submucosal dissection using clip and line: a feasibility study

    Yamasaki, Yasushi; Takeuchi, Yoji; Uedo, Noriya; Kato, Minoru; Hamada, Kenta; Aoi, Kenji; Tonai, Yusuke; Matsuura, Noriko; Kanesaka, Takashi; Yamashina, Takeshi; Akasaka, Tomofumi; Hanaoka, Noboru; Higashino, Koji; Ishihara, Ryu; Iishi, Hiroyasu


    Background and study aims: Colonic endoscopic submucosal dissection (ESD) is a challenging procedure because it is often difficult to maintain good visualization of the submucosal layer. To facilitate colonic ESD, we designed a novel traction method, namely traction-assisted colonic ESD using clip and line (TAC), and investigated its feasibility. Patients and methods: We retrospectively analyzed 23 patients with large colonic superficial lesions who had undergone TAC. The main outcome was the procedural success rate of TAC, which we defined as successful, sustained application of clip and line to the lesion until the end of the procedure. Results: The procedural success rate of TAC was 87 % (20/23). In all three unsuccessful cases, the lesions were in the proximal colon and the procedure times over 100 minutes. The overall mean procedure time was 61 min (95 % confidence interval, 18 – 172 min). We achieved en bloc resections of all lesions. There were no perforations or fatal adverse events. Conclusions: TAC is feasible and safe for colonic ESD and may improve the ease of performing this procedure. PMID:26793785

  16. Transcondylar traction as a closed reduction technique in vertically unstable pelvic ring disruption.

    Thaunat, M; Laude, F; Paillard, P; Saillant, G; Catonné, Y


    Little information is provided in the literature describing an efficient reduction technique for pelvic ring disruption. The aim of this study is to assess the use of the transcondylar traction as a closed reduction technique for vertically unstable fracture-dislocations of the sacro-iliac joint. Twenty-four pelvic ring disruptions were treated with attempted closed reduction followed by percutaneous screw fixation. Transcondylar traction was used as a closed reduction technique. Closed reduction to within 1 cm of residual displacement was obtained in all cases. No incidence of infection, digestive, cutaneous, or vascular complications occurred. We observed secondary displacement in three patients. Correction of the vertical displacement is better achieved when performed within 8 days after the trauma. Two posterior screws and a complementary anterior fixation is typically required to avoid further displacement in case of sacral fractures. However, an open approach should be preferred in both cases of crescent iliac fracture-sacroiliac dislocation and transforaminal fracture associated with peripheral neurological deficit. A vertical sacral fracture should make the surgeon more wary of fixation failure and loss of reduction.

  17. Radiographic evaluation of the use of transverse traction device in vertebral arthrodesis for degenerative diseases

    Edgar Takao Utino


    Full Text Available OBJECTIVE: Perform radiographic analysis of the use of Transverse Traction Device (DTT with respect to fusion rate in patients submitted to vertebral arthrodesis for degenerative lumbar diseases. METHODS: We selected x-ray images on anteroposterior, lateral and oblique views and with maximum flexion and extension dynamics of 23 patients submitted to posterolateral arthrodesis of the lumbar spine with a minimum follow-up period of six months. The images were evaluated and classified by the Linovitz's system by two spine surgeons. RESULTS: We evaluated the radiographs of 23 patients after the minimum postoperative period of 6 months and of these, 11 have used DTT. With regard to the consolidation rate, seven patients (63.6% in the group of DTT were classified as fusion as well as six patients (50% who were not submitted to the treatment. There was no statistical difference between the groups regarding the consolidation rate. CONCLUSION: The use of transverse traction device in this study showed no significant difference in the rate of consolidation in radiographic evaluation. Studies on the effective participation of this device in the stability of pedicle fixation systems are still lacking in the literature.

  18. Methods of the aerodynamical experiments with simulation of massflow-traction ratio of the power unit

    Lokotko, A. V.


    Modeling massflow-traction characteristics of the power unit (PU) may be of interest in the study of aerodynamic characteristics (ADC) aircraft models with full dynamic likeness, and in the study of the effect of interference PU. These studies require the use of a number of processing methods. These include: 1) The method of delivery of the high-pressure body of jets model engines on the sensitive part of the aerodynamic balance. 2) The method of estimate accuracy and reliability of measurement thrust generated by the jet device. 3) The method of implementation of the simulator SU in modeling the external contours of the nacelle, and the conditions at the inlet and outlet. 4) The method of determining the traction simulator PU. 5) The method of determining the interference effect from the work of power unit on the ADC of model. 6) The method of producing hot jets of jet engines. The paper examines implemented in ITAM methodology applied to testing in a supersonic wind tunnel T-313.


    A. V. Matyuschenko


    Full Text Available Purpose. The study was conducted to analyze thermal state of the traction permanent magnet synchronous motor for mine electric battery locomotive when operating in continuous and short-time duty modes. These operating modes are selected for study, as they are typical for mine electric locomotives. Methodology. Thermal calculation was performed by means of FEM in three-dimensional formulation of problem using Jmag-Designer. Results. The modeling results of thermal state of the PMSM in continuous and short-time duty operation modes showed good agreement with experimental results. The results showed that the temperature of PM is higher than temperature of the stator winding in continuous operation mode. It was found that PM temperature might reach excessive values because of the high presence of eddy current losses in neodymium PM. Therefore, special attention in the design and testing of PMSM should be paid to the temperature of PM in various operation modes. Practical value. It was recommended to use high temperature permanent magnets in traction PMSM to avoid demagnetization of PM and performance degradation.

  20. Estudo laboratorial de teste de resistência ao tracionamento da resina composta fotopolimerizável Fill Magic® destinada à colagem de braquetes para tracionamento ortodôntico de dentes retidos Laboratorial study to test traction resistance of Fill Magic® light-cured resin intended for orthodontic traction of unerupted teeth

    Felipe Ladeira Pereira


    Full Text Available OBJETIVO: Avaliar a resistência à tração de duas resinas utilizadas para colagem de acessórios para tracionamento dentário. METODOLOGIA: o presente estudo comparou a adesividade e praticidade de duas resinas destinadas ao tracionamento ortodôntico de dentes impactados: a Concise® da 3M®, presente no mercado há alguns anos e tida como referência na realização deste procedimento; e a Fill Magic® da Vigodent®, cuja técnica é julgada mais simples pelo fabricante. Foram incluídos 40 terceiros molares em corpos de prova e estes divididos em dois grupos de 20, um para cada resina. Uma vez colados os braquetes, os corpos de prova foram submetidos à força de tração horizontal (10 de cada grupo e vertical (10 de cada grupo, até que os braquetes se soltassem. Os valores obtidos na máquina universal de ensaios foram registrados e comparados por meio de médias para que fosse possível estabelecer as vantagens e desvantagens de cada resina. RESULTADO E CONCLUSÃO: apesar dos valores obtidos com a resina Fill Magic® terem sido menores que os da resina Concise®, comprovou-se que eles são suficientes para a realização do tracionamento ortodôntico.AIM: comparisson of two composite adhesives used for orthodontic traction procedures. METHODS: this article compared the bonding capability and practice of two resins for direct orthodontic traction: the 3M®'s Concise®, been sold in the market for a few years and the reference for this kind of procedure; and Vigodent®'s Fill Magic®, which technique is much simpler according to the manufacturer. Forty third molars were included into acrylic resin and divided in two groups of 20, one for each resin. Once the brackets were bonded, the specimens were submitted to horizontal force (10 of each group and vertical (10 of each group, till the bracket got lost. The score obtained in the universal testing machine were recorded and compared by the average to set the advantages and disadvantages of

  1. The Effects of Stretching with Lumbar Traction on VAS and Oswestry Scales of Patients with Lumbar 4-5 Herniated Intervertebral Disc.

    Yang, Hae-Sun; Yoo, Won-Gyu


    [Purpose] This study investigated the effect of stretching with lumbar traction on VAS and Oswestry scale scores of lumbar 4-5 herniated intervertebral disc (HIVD) patients. [Subjects] We recruited 20 lumbar 4-5 HIVD patients. [Methods] We performed stretching with lumbar traction for lumbar 4-5 HIVD patients during 4 weeks. The VAS and Oswestry scales were measured before and 4 weeks after the intervention. [Results] The results showed a significant decrease in VAS scale scores for stretching with lumbar traction in lumbar 4-5 HIVD patients, from 18±1.29 to 2.1±1.35. The Oswestry scale scores also decreased significantly, from 20.35±2.01 to 3.5±2.84, after stretching with lumbar traction. [Conclusion] Thus, we suggest stretching with lumbar traction for lumbar 4-5 HIVD patients.

  2. Open reduction and internal fixation aided by intraoperative 3-dimensional imaging improved the articular reduction in 72 displaced acetabular fractures

    Eckardt, Henrik; Lind, Dennis; Toendevold, Erik


    Background and purpose - During acetabular fracture surgery, the acetabular roof is difficult to visualize with 2-dimensional fluoroscopic views. We assessed whether intraoperative 3-dimensional (3D) imaging can aid the surgeon to achieve better articular reduction and improve implant fixation....... Patients and methods - We operated on 72 acetabular fractures using intraoperative 3D imaging and compared the operative results, duration of surgery, and complications with those for 42 consecutive acetabular fracture operations conducted using conventional fluoroscopic imaging. Postoperative reduction...... was evaluated on reconstructed coronal and sagittal images of the acetabulum. Results - The fracture severity and patient characteristics were similar in the 2 groups. In the 3D group, 46 of 72 patients (0.6) had a perfect result after open reduction and internal fixation, and in the control group, 17 of 42 (0...

  3. A 3-dimensional digital atlas of the ascending sensory and the descending motor systems in the pigeon brain.

    Güntürkün, Onur; Verhoye, Marleen; De Groof, Geert; Van der Linden, Annemie


    Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-based atlas of the pigeon brain becomes essential. Using multiple imaging protocols, we delineated diverse ascending sensory and descending motor systems as well as the hippocampal formation. This pigeon brain atlas can easily be used to determine the stereotactic location of identified neural structures at any angle of the head. In addition, the atlas is useful to find the optimal angle of sectioning for slice experiments, stereotactic injections and electrophysiological recordings. This pigeon brain atlas is freely available for the scientific community.

  4. Numerical simulation of recalescence of 3-dimensional isothermal solidification for binary alloy using phase-field approach

    ZHU Chang-sheng; XIAO Rong-zhen; WANG Zhi-ping; FENG Li


    A accelerated arithmetic algorithm of the dynamic computing regions was designed, and 3-dimensional numerical simulation of isothermal solidification for a binary alloy was implemented. The dendritic growth and the recalescence of Ni-Cu binary alloy during the solidification at different cooling rates were investigated. The effects of cooling rate on dendritic patterns and microsegregation patterns were studied. The computed results indicate that, with the increment of the cooling rate, the dendritic growth velocity increases, both the main branch and side-branches become slender, the secondary dendrite arm spacing becomes smaller, the inadequate solute diffusion in solid aggravates, and the severity of microsegregation ahead of interface aggravates. At a higher cooling rate, the binary alloy presents recalescence; while the cooling rate is small, no recalescence occurs.

  5. Uterine volume and endometrial thickness in healthy girls evaluated by ultrasound (3-dimensional) and magnetic resonance imaging

    Hagen, Casper P; Mouritsen, Annette; Mieritz, Mikkel G;


    OBJECTIVE: To report normative data on uterine volume and endometrial thickness in girls, according to pubertal stages; to evaluate factors that affect uterine volume; and to compare transabdominal ultrasound (TAUS) and magnetic resonance imaging (MRI). DESIGN: Cross-sectional study of a nested...... cohort of girls participating in The Copenhagen Mother-Child Cohort. SETTING: General community. PATIENT(S): One hundred twenty-one healthy girls, aged 9.8-14.7 years. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Clinical examination, including pubertal breast stage (Tanner classification: B1-B5......). Uterine volume: ellipsoid TAUS (n = 112) and 3-dimensional TAUS (n = 111); ellipsoid MRI (n = 61). Endometrial thickness: TAUS (n = 110) and MRI (n = 60). RESULT(S): Uterine volume and endometrial thickness were positively correlated with pubertal stages; e.g., ellipsoid TAUS: r = 0.753, and endometrium...

  6. New insights into the coronary artery bifurcation hypothesis-generating concepts utilizing 3-dimensional optical frequency domain imaging.

    Farooq, Vasim; Serruys, Patrick W; Heo, Jung Ho; Gogas, Bill D; Okamura, Takayuki; Gomez-Lara, Josep; Brugaletta, Salvatore; Garcìa-Garcìa, Hector M; van Geuns, Robert Jan


    Coronary artery bifurcations are a common challenging lesion subset accounting for approximately 10% to 20% of all percutaneous coronary interventions. The provisional T-stenting approach is generally recommended as the first-line management of most lesions. Carina shift is suggested to be the predominant mechanism of side-branch pinching during provisional T-stenting and has been indirectly inferred from bench work and other intravascular imaging modalities. Offline 3-dimensional (3D) reconstructions of patients studied in the first-in-man trial of the high-frequency (160 frames/s) Terumo optical frequency domain imaging system were undertaken using volume-rendering software. Through a series of 3D reconstructions, several novel hypothesis-generating concepts are presented.

  7. 3-dimensional organic Dirac-line material due to non-symmorphic symmetry: a data mining approach

    Geilhufe, R Matthias; Borysov, Stanislav S; Balatsky, Alexander V


    A data mining study of electronic Kohn-Sham band structures was performed to identify Dirac materials within the Organic Materials Database (OMDB). Out of that, the 3-dimensional organic crystal 5,6-Bis(trifluoromethyl)-2-methoxy-1H-1,3-diazepine was found to host different Dirac line-nodes within the band structure. From a group theoretical analysis, it is possible to distinguish between Dirac line-nodes occurring due to 2-fold degenerate energy levels protected by the monoclinic crystalline symmetry and 2-fold degenerate accidental crossings protected by the topology of the electronic band structure. The obtained results can be generalized to all materials having the space group $P2_1/c$ ($\\#14$, $C^5_{2h}$) by introducing three distinct topological classes.

  8. 天津滨海二期车辆无牵引无制动故障分析%Failure Analysis on Traction and Brake for Tianjin Binhai Phase II Vehicle

    米志宏; 龙贤


    天津滨海二期车辆运行偶尔出现全车无常用制动力,还经常出现牵引时各级牵引力输出均为最大牵引力,司机按压紧急制动按钮停车,之后通过重新启动编码器电源的方式恢复。造成列车欠标停车和晚点,经过长时间跟踪调查,确定为编码器供电电源受外部干扰所致,为编码器电源增加浪涌抑制器后,该故障现象消除。%The Tianjin Binhai Phase II vehicles suffer occasional cases of running without braking force, and there are often happenings of towing traction output levels reaching maximum traction, which requires driver to press emergency stop button, then restart the encoder power supply to resume operation. This has caused train delays and parking not to sign position. After a long-term follow-up survey, the problem is identiifed as external interference on encoder power supply. The problem is solved after installing surge suppressor for encoder power supply.

  9. Monte Carlo Simulation of 3-dimensional Ising Model%三维Ising模型的蒙特卡罗模拟

    黄纯青; 邓绍军


    采用蒙特卡罗(Monte Cado)重点抽样法对三维Ising模型进行计算机模拟,测量无外磁场时三维Ising模型中自旋键链的能量、磁化强度、比热及磁化率的统计平均值与标准误差(不确定度).结果表明,三维Ising模型在无外磁场时存在自发磁化现象,铁磁→非铁磁相变临界点在J/(kBTc=0.222 0,或居里温度Tc=4.500 0处.并研究存在外磁场时上述物理量随温度与外磁场的变化规律,给出物理解释.%A 3-dimensional Ising model is simulated with Monte Carlo importance sampling method. Statistical values of energy, strength of magnetization, specific heat and rate of magnetization of spin links as well as their standard errors (uncertainties) are measured. 3-dimensional Ising model shows spontaneous magnetization with no exterior magnetic field. Critical point of phase transformation is at J/( k_BT_c ) = 0.222 0 or T_c = 4.500 0. Phase transformation at high temperature disappears with exterior magnetic field. Relationship between physical quantities, temperature and exterior magnetic field is investigated and analyzed.

  10. Influence of the implant diameter with different sizes of hexagon: analysis by 3-dimensional finite element method.

    Pellizzer, Eduardo Piza; Verri, Fellippo Ramos; de Moraes, Sandra Lúcia Dantas; Falcón-Antenucci, Rosse Mary; de Carvalho, Paulo Sérgio Perri; Noritomi, Pedro Yoshito


    The aim of this study was to evaluate the stress distribution in implants of regular platforms and of wide diameter with different sizes of hexagon by the 3-dimensional finite element method. We used simulated 3-dimensional models with the aid of Solidworks 2006 and Rhinoceros 4.0 software for the design of the implant and abutment and the InVesalius software for the design of the bone. Each model represented a block of bone from the mandibular molar region with an implant 10 mm in length and different diameters. Model A was an implant 3.75 mm/regular hexagon, model B was an implant 5.00 mm/regular hexagon, and model C was an implant 5.00 mm/expanded hexagon. A load of 200 N was applied in the axial, lateral, and oblique directions. At implant, applying the load (axial, lateral, and oblique), the 3 models presented stress concentration at the threads in the cervical and middle regions, and the stress was higher for model A. At the abutment, models A and B showed a similar stress distribution, concentrated at the cervical and middle third; model C showed the highest stresses. On the cortical bone, the stress was concentrated at the cervical region for the 3 models and was higher for model A. In the trabecular bone, the stresses were less intense and concentrated around the implant body, and were more intense for model A. Among the models of wide diameter (models B and C), model B (implant 5.00 mm/regular hexagon) was more favorable with regard to distribution of stresses. Model A (implant 3.75 mm/regular hexagon) showed the largest areas and the most intense stress, and model B (implant 5.00 mm/regular hexagon) showed a more favorable stress distribution. The highest stresses were observed in the application of lateral load.

  11. Bilateral flight muscle activity predicts wing kinematics and 3-dimensional body orientation of locusts responding to looming objects.

    McMillan, Glyn A; Loessin, Vicky; Gray, John R


    We placed locusts in a wind tunnel using a loose tether design that allowed for motion in all three rotational degrees of freedom during presentation of a computer-generated looming disc. High-speed video allowed us to extract wing kinematics, abdomen position and 3-dimensional body orientation. Concurrent electromyographic (EMG) recordings monitored bilateral activity from the first basalar depressor muscles (m97) of the forewings, which are implicated in flight steering. Behavioural responses to a looming disc included cessation of flight (wings folded over the body), glides and active steering during sustained flight in addition to a decrease and increase in wingbeat frequency prior to and during, respectively, an evasive turn. Active steering involved shifts in bilateral m97 timing, wing asymmetries and whole-body rotations in the yaw (ψ), pitch (χ) and roll (η) planes. Changes in abdomen position and hindwing asymmetries occurred after turns were initiated. Forewing asymmetry and changes in η were most highly correlated with m97 spike latency. Correlations also increased as the disc approached, peaking prior to collision. On the inside of a turn, m97 spikes occurred earlier relative to forewing stroke reversal and bilateral timing corresponded to forewing asymmetry as well as changes in whole-body rotation. Double spikes in each m97 occurred most frequently at or immediately prior to the time the locusts turned, suggesting a behavioural significance. These data provide information on mechanisms underlying 3-dimensional flight manoeuvres and will be used to drive a closed loop flight simulator to study responses of motion-sensitive visual neurons during production of realistic behaviours.

  12. Changes in stature during and after spinal traction in young male subjects Alterações na estatura antes e após a tração vertebral em homens jovens

    ALF Rodacki


    Full Text Available BACKGROUND: Spinal traction is a relatively popular procedure for increasing the intervertebral space by applying separating forces. The parameters of time and magnitude of the traction forces may influence the outcomes from this procedure and need to be investigated. The duration of the benefits derived from traction is unknown and needs to be determined so that physiotherapists can provide better and more effective treatments. OBJECTIVE: This study analyzed the relationship between load magnitude and time during spinal traction in relation to stature variations. Traction effect duration was also analyzed. METHOD: Fifteen healthy male subjects (23.1 ± 5.77 years; 1.80 ± 0.17 m and 87.0 ± 9.6 kg were assessed under three traction conditions (0, 30 and 60% of body weight, BW of 42 minutes. Stature variation was used to determine intervertebral disc height variation. Stature was assessed every 7 minutes during traction of 42 minutes and every 5 minutes for 45 minutes after traction ceased. RESULTS: 0 and 30% BW traction produced similar gains (6.09 ± 1.89 mm, 5.70 ± 1.88 mm, respectively; p>0.05, while these were smaller (pCONTEXTUALIZAÇÃO: A tração sobre a coluna vertebral é um procedimento relativamente popular para aumentar o espaço inter-vertebral pela aplicação de forças de separação. Os parâmetros de tempo e magnitude da força aplicada podem influenciar os resultados desse procedimento e ainda precisam ser investigados. A duração dos benefícios derivados da tração não é conhecida e precisa ser determinada para que fisioterapeutas possam prover tratamentos melhores e mais eficientes. OBJETIVO: Este estudo analisou a relação entre a magnitude de carga e de tempo durante a tração vertebral sobre as variações de estatura, bem como a duração deste efeito. MÉTODOS: Quinze sujeitos saudáveis do sexo masculino (23,1 ± 5,77 anos; 1,80 ± 0,17 m e 87,0 ± 9,6 Kg foram mensurados sob três condições (0, 30 e 60% PC

  13. Labor Force

    Occupational Outlook Quarterly, 2012


    The labor force is the number of people ages 16 or older who are either working or looking for work. It does not include active-duty military personnel or the institutionalized population, such as prison inmates. Determining the size of the labor force is a way of determining how big the economy can get. The size of the labor force depends on two…

  14. Establishment of a finite element model of lumbar spine and simulation under different traction angles%腰椎有限元模型的建立与不同角度牵引条件下的仿真研究

    刘治华; 徐新伟; 管文浩; 黄玉锋; 王晓东; 苏建勇


    Aim: To explore the effect of traction in different angles on lumbar discs traction in different angles . Methods:A three-dimensional finite element model of human lumbar segments L 1~5 ,and S1 was established based on med-ical CT images , and there were 148 943 nodes and 91 636 units in the model .Forces of two groups which size were respec-tively 320 and 200 N were exerted on the model based on clinical experience to simulate the traction under different traction angles such as 0°,5°,10°,15°,20°and 25°when the human body was lying down .Results:When the traction angle was 10°,the change of L4/5 was the largest,which was 2.42 mm;when the traction angle was 15°,the change of L3/4 was the lar-gest,which was 2.44 mm;when the traction angle was 20°,the change of L2/3 was the largest,which was 2.43 mm;When the traction angle was 25°,the change of L1/2 was the largest,which was 2.46 mm.Conclusion:The specific lesion of in-tervertebral discs can be better treated by adjusting the traction angle .%目的:探讨不同角度牵引对腰椎间盘的影响。方法:基于医用CT图像建立人体腰椎L1~5、S1节段的三维有限元模型,模型共有148943个节点,91636个单元。对模型施加320 N的牵引力,模拟人体平躺时斜向上0°、5°、10°、15°、20°和25°牵引。结果:与其他几个牵引角度相比,当斜向上10°牵引时,椎间盘L4/5伸长量最大,为2.42 mm;斜向上15°牵引时,椎间盘L3/4伸长量最大,为2.44 mm;斜向上20°牵引时,椎间盘L2/3伸长量最大,为2.43 mm;斜向上25°牵引时,椎间盘L1/2伸长量最大,为2.46 mm。结论:通过调整牵引角度可以对病变的腰椎间盘进行有针对性的治疗。

  15. Rupture dynamics along bimaterial interfaces: a parametric study of the shear-normal traction coupling

    Scala, Antonio; Festa, Gaetano; Vilotte, Jean-Pierre


    Earthquake ruptures often develop along faults separating materials with dissimilar elastic properties. Due to the broken symmetry, the propagation of the rupture along the bimaterial interface is driven by the coupling between interfacial sliding and normal traction perturbations. We numerically investigate in-plane rupture growth along a planar interface, under slip weakening friction, separating two dissimilar isotropic linearly elastic half-spaces, and we perform a parametric study of the classical Prakash-Clifton regularisation, for different material contrasts. In particular the mesh-dependence and the regularisation-dependence of the numerical solutions are analysed in this parameter space. When the regularisation involves a slip-rate dependent relaxation time, a characteristic sliding distance is identified below which numerical solutions no longer depend on the regularisation parameter, i.e. they are physically well-posed solutions. Such regularisation provides an adaptive high-frequency filter of the slip-induced normal traction perturbations, following the dynamic shrinking of the dissipation zone during the acceleration phase. In contrast, a regularisation involving a constant relaxation time leads to numerical solutions that always depend on the regularisation parameter since it fails in adapting to the shrinking of the process zone. Dynamic regularisation is further investigated using a non-local regularisation based on a relaxation time that depends on the dynamic length of the dissipation zone. Such reformulation is shown to provide similar results as the dynamic time scale regularisation proposed by Prakash-Clifton when the slip rate is replaced by the maximum slip rate along the sliding interface. This leads to the identification of a dissipative length scale associated with the coupling between interfacial sliding and normal traction perturbations, together with a scaling law between the maximum slip rate and the dynamic size of the process zone

  16. Perfluorocarbon-perfused 23 gauge three-dimensional vitrectomy for complicated diabetic tractional retinal detachment

    Quiroz-Mercado H


    Full Text Available Raul Velez-Montoya1, Jose Luis Guerrero-Naranjo2, Gerardo Garcia-Aguirre2, Virgilio Morales-Cantón2, Jans Fromow-Guerra2, Hugo Quiroz-Mercado31Department of Ophthalmology, University of Colorado Health and Science Center, Rocky Mountain Lions Eye Institute, University of Colorado School of Medicine, CO, USA; 2Retina Department, Asociación para Evitar la Ceguera en México IAP, México City, México; 3Department of Ophthalmology, Denver Health Medical Center, University of Colorado School of Medicine, Denver, CO, USABackground: Perfluorocarbon liquid (PCL-perfused vitrectomy has been shown in previous studies to be feasible, safe, and to have advantages in managing complicated cases of tractional retinal detachment. The present study had the objectives of describing the anatomical results and measuring surgical time and PCL consumption when combining PCL-perfused techniques with modern vitrectomy equipment.Methods: A prospective, interventional consecutive case series was investigated. We enrolled patients with diabetic tractional retinal detachment, complicated by proliferative vitreoretinopathy and poor vision. A 23 gauge PCL-perfused vitrectomy was done with three-dimensional settings. During the procedure, we assessed the degree of surgical bleeding, visualization quality, and difficulty of membrane dissections. Visual acuity, intraocular pressure, and anatomical success were assessed at one and 3 months of follow-up.Results: Twelve patients were enrolled in this study. There were no statistical significant changes in intraocular pressure and visual acuity throughout the follow-up period. Surgery was performed in a hemorrhage-free environment in almost all cases, with good visualization and low technical difficulty. The mean complete surgical time was 94.92 ± 25.03 minutes. The mean effective vitrectomy time was 22.50 ± 19.04 minutes and the mean PCL consumption was 25.08 ± 9.76 mL, with a speed of 1.11 mL/minute. Anatomical success was

  17. MR findings associated with positive distraction of the hip joint achieved by axial traction

    Suter, Aline; Dietrich, Tobias J.; Maier, Matthias; Pfirrmann, Christian W.A. [Radiology, Orthopedic University Hospital Balgrist, Zurich (Switzerland); University of Zurich, Faculty of Medicine, Zurich (Switzerland); Dora, Claudio [Orthopedic University Hospital Balgrist, Orthopedic Surgery, Zurich (Switzerland); University of Zurich, Faculty of Medicine, Zurich (Switzerland)


    To determine which MR-arthrography findings are associated with positive hip joint distraction. One hundred patients with MR arthrography of the hip using axial traction were included. Traction was applied during the MR examination with an 8 kg (females) or 10 kg (males) water bag, attached to the ankle over a deflection pulley. Fifty patients showing joint space distraction were compared to an age- and gender-matched control group of 50 patients that did not show a joint distraction under axial traction. Two radiologists assessed the neck-shaft angle, lateral and anterior center-edge (CE) angles, CE angles in the transverse plane, extrusion index of the femoral head, acetabular depth, alpha angle, acetabular version, ligamentum teres, joint capsule and ligaments, iliopsoas tendon and the labrum. Mean joint space distraction in the study group was 0.9 ± 0.6 mm. Patients with positive joint space distraction had significantly higher neck-shaft angles (control group 131.6 ± 5.4 /study group 134.1 ± 6.1 , p < 0.05), smaller lateral CE angles (38.1 ± 5.9 /34.6 ± 7.2 , p < 0.05), smaller overall transverse CE angles (161.4 ± 9.9 /153.6 ± 9.6 , p < 0.001), smaller acetabular depth (4.1 ± 2.4 mm/5.8 ± 2.5 mm, p < 0.01), higher alpha angles (53.5 ± 7.8 /59.2 ± 10.1 , p < 0.01) and a thicker ligamentum teres (4.7 ± 1.4 mm/5.4 ± 1.8 mm, p < 0.05). The other parameters revealed no significant differences. ICC values for interobserver agreement were 0.71-0.95 and kappa values 0.43-0.92. Increased neck-shaft angles, small CE angles, small acetabular depth, higher alpha angles and a thick ligamentum teres are associated with positive joint distraction. (orig.)

  18. Transpalatal screw traction: a simple technique for the management of sagittal fractures of the maxilla and palate.

    Ma, D; Guo, X; Yao, H; Chen, J


    Sagittal fractures of the maxilla and palate are uncommon in clinical practice. Current methods for the management of such fractures have advantages and limitations. The authors present the simple and practical technique of bilateral transpalatal screw traction to manage this fracture type.

  19. Orthodontic Management with Traction and Asymmetric Extraction for Multiple Impacted Permanent Maxillary Teeth – A Case Report

    Niu, Qiannan; Zhang, Liang; Dai, Juan; Li, Feifei; Feng, Xue


    Multiple impacted teeth are a rare eruption disturbance that increases the case complexity. In this article, we described a 13-year-old boy whose 5 permanent maxillary teeth were not erupted although their root formation was complete. The orthodontic treatment with traction and asymmetric extraction was performed to achieve a significantly improved functional and esthetic result. PMID:27857816

  20. The effect of cervical traction combined with neural mobilization on pain and disability in cervical radiculopathy. A case report.

    Savva, Christos; Giakas, Giannis


    Cervical radiculopathy is the result of cervical nerve root pathology that may lead to chronic pain and disability. Although manual therapy interventions including cervical traction and neural mobilization have been advocated to decrease pain and disability caused by cervical radiculopathy, their analgesic effect has been questioned due to the low quality of research evidence. The purpose of this paper is to present the effect of cervical traction combined with neural mobilization on pain and disability in a patient experiencing cervical radiculopathy. A 52-year-old woman presented with a 2 month history of neurological cervico-brachial pain and whose presentation was consistent with cervical radiculopathy. Cervical traction and a slider neural mobilization of the medial nerve were applied simultaneously to reduce the patient's pain and disability measured at baseline and at 2 and 4 weeks using the Numeric Pain Rating Scale, the Neck Disability Index and the Patient-Specific Functional Scale. Improvements in all outcome measures were noted over a period of four weeks. Scores in all outcome measures revealed that the patient's pain had almost disappeared and that she was able to perform her household chores and job tasks without difficulties and limitations. In conclusion, the findings of this study support that the application of cervical traction combined with neural mobilization can produce significant improvements in terms of pain and disability in cervical radiculopathy.

  1. Inverse extraction of interfacial tractions from elastic and elasto-plastic far-fields by nonlinear field projection

    Chew, Huck Beng


    Determining the tractions along a surface or interface from measurement data in the far-fields of nonlinear materials is a challenging inverse problem which has significant engineering and nanoscience applications. Previously, a field projection method was established to identify the crack-tip cohesive zone constitutive relations in an isotropic elastic solid (Hong and Kim, 2003. J. Mech. Phys. Solids 51, 1267). In this paper, the field projection method is further generalized to extracting the tractions along interfaces bounded by nonlinear materials, both with and without pre-existing cracks. The new formulation is based on Maxwell-Betti's reciprocal theorem with a reciprocity gap associated with nonlinear materials. We express the unknown normal and shear tractions along the interface in terms of the Fourier series, and use specially constructed analytical auxiliary fields in the reciprocal theorem to extract the unknown Fourier coefficients from far-field data; the reciprocity gap in the formulation is iteratively determined with a set of numerical algorithms. Our detailed numerical experiments demonstrate that this nonlinear field projection method (NFPM) is well-suited for extracting the interfacial tractions from the far-field data of any nonlinear elastic or elasto-plastic material with known constitutive laws. Applications of the NFPM to experiments and atomistic simulations are discussed.

  2. A Combined Treatment of Scalp Acupuncture and Traction in 108 Cases of Prolapse of the Lumbar Intervertebral Disc


    @@ Prolapse of the lumbar intervertebral disc is a syndrome commonly seen in clinic. The main manifestation is pain in the lumbar region radiating to the lower limbs. In the treatment of this disease, the author has employed traction together with scalp needling, and obtained quite good therapeutic effects. A report follows.

  3. Regulation of unbalanced electromagnetic moment in mutual loading systems of electric machines of traction rolling stock and multiple unit of mainline and industrial transport

    A. M. Afanasov


    Full Text Available Purpose. The research data are aimed to identify the regulatory principles of unbalanced electromagnetic moment of mutually loaded electric machines of traction rolling stock and multiple unit of main and industrial transport. The purpose of this study is energy efficiency increase of the testing of traction electric machines of direct and pulse current using the improvement methods of their mutual loading, including the principles of automatic regulation of mutual loading system. Methodology. The general theoretical provisions and principles of system approach to the theoretical electric engineering, the theory of electric machines and theoretical mechanics are the methodological basis of this research. The known methods of analysis of electromagnetic and electromechanical processes in electrical machines of direct and pulse current are used in the study. Methods analysis of loading modes regulation of traction electric machines was conducted using the generalized scheme of mutual loading. It is universal for all known methods to cover the losses of idling using the electric power. Findings. The general management principles of mutual loading modes of the traction electric machines of direct and pulse current by regulating their unbalanced electric magnetic moment were developed. Regulatory options of unbalanced electromagnetic moment are examined by changing the difference of the magnetic fluxes of mutually loaded electric machines, the current difference of electric machines anchors, the difference of the angular velocities of electric machines shafts. Originality. It was obtained the scientific basis development to improve the energy efficiency test methods of traction electric machines of direct and pulse current. The management principles of mutual loading modes of traction electric machines were formulated. For the first time it is introduced the concept and developed the principles of regulation of unbalanced electromagnetic moment in

  4. Dispersion Forces

    Buhmann, Stefan Yoshi


    In this book, a modern unified theory of dispersion forces on atoms and bodies is presented which covers a broad range of advanced aspects and scenarios. Macroscopic quantum electrodynamics is shown to provide a powerful framework for dispersion forces which allows for discussing general properties like their non-additivity and the relation between microscopic and macroscopic interactions. It is demonstrated how the general results can be used to obtain dispersion forces on atoms in the presence of bodies of various shapes and materials. Starting with a brief recapitulation of volume I, this volume II deals especially with bodies of irregular shapes, universal scaling laws, dynamical forces on excited atoms, enhanced forces in cavity quantum electrodynamics, non-equilibrium forces in thermal environments and quantum friction. The book gives both the specialist and those new to the field a thorough overview over recent results in the field. It provides a toolbox for studying dispersion forces in various contex...

  5. The characteristics of the combustion process occurring under real operating conditions of traction

    Longwic, R.; Sander, P.


    The authors deal with the issues of the Diesel engine under dynamic conditions. The conditions of the dynamic operation of the engine have most frequently been mapped by the method of free acceleration of the engine caused by the change of the position of the fuel dose lever. The article presents the results of indication of the traction Diesel engine under real operating conditions. This allows for the use of a mobile system to indicate the AVL engine built in the vehicle in research. We analysed a number of thermodynamic parameters of the combustion process in various dynamic states, typical for the process of actual operation of the engine, such as working in start-up conditions and immediately after, working in conditions of acceleration and coasting. Formulated conclusions significantly expand the area of knowledge concerning the functioning of the internal combustion engine in dynamic conditions.

  6. Helical Configurations of Elastic Rods in the Presence of Interfacial Traction

    王永昭; 张琪昌; 王炜; 韩建鑫


    The Kirchhoff thin elastic rod models are always the important basis to explore the configuration mecha-nism of the flexible structures in both the macroscopic and microscopic scale. As a continuum model of DNA, a thin elastic rod subjected to interfacial interactions is used to investigate the helical equilibrium configuration of DNA in salt solution. In this paper, the Kirchhoff's equations in the presence of interfacial traction and the free energy density functions of different configurations are studied. The transition formula of the free energy between B-DNA and Z-DNA is obtained, and the results show that the free energy of the transition is mainly determined by the salt concentra-tion, which agrees well with the experimental data.

  7. First-order system least squares for the pure traction problem in planar linear elasticity

    Cai, Z.; Manteuffel, T.; McCormick, S.; Parter, S.


    This talk will develop two first-order system least squares (FOSLS) approaches for the solution of the pure traction problem in planar linear elasticity. Both are two-stage algorithms that first solve for the gradients of displacement, then for the displacement itself. One approach, which uses L{sup 2} norms to define the FOSLS functional, is shown under certain H{sup 2} regularity assumptions to admit optimal H{sup 1}-like performance for standard finite element discretization and standard multigrid solution methods that is uniform in the Poisson ratio for all variables. The second approach, which is based on H{sup -1} norms, is shown under general assumptions to admit optimal uniform performance for displacement flux in an L{sup 2} norm and for displacement in an H{sup 1} norm. These methods do not degrade as other methods generally do when the material properties approach the incompressible limit.

  8. Transurethral resection of tension-free vaginal tape under tactile traction.

    Quiroz, Lieschen H; Cundiff, Geoffrey W


    Urethral erosion is a rare complication after the tension-free vaginal tape (TVT) procedure. Surgical management of this complication is challenging due to the potential for significant patient morbidity. A 50-year-old patient presented with lower urinary tract symptoms (LUTS) and incomplete voiding, 6 years after a TVT procedure performed for stress incontinence. An attempt at cystoscopy revealed an almost complete occlusion of the urethral lumen by a urethral erosion of the polypropylene mesh. A transurethral resection was performed under tactile traction. This procedure is a minimally invasive approach that avoids the need for a transvaginal procedure. Careful cystourethroscopy should be performed in patients presenting with new lower LUTS after TVT in order to avoid a delay in diagnosing a mesh erosion.

  9. Lead-acid traction batteries for electric road vehicle propulsion Directions for research and development

    Rand, D. A. J.


    Little information exists on the behavior of lead-acid batteries operating under the duty cycles normal to electric road vehicle service. Important battery requirements for the propulsion of traffic-compatible electric vehicles include a deep-discharge capability at high efficiencies of active material utilization, and a long cycle life. In order to optimize power-source characteristics to meet these criteria, especially for passenger cars, it is necessary to gain full knowledge of the influence of actual vehicle service on the performance of traction batteries. This article defines areas in which both fundamental and applied work are required to achieve this aim based on the current performance of the lead-acid system.

  10. Sudden progression of lumbar disk protrusion during vertebral axial decompression traction therapy.

    Deen, H Gordon; Rizzo, Thomas D; Fenton, Douglas S


    Vertebral axial decompression (VAX-D) is a form of spinal traction that is widely promoted as an effective and safe treatment of degenerated and herniated lumbar intervertebral disks. Information targeted at the general public emphasizes that the treatment is completely risk-free. We describe a patient with a large lumbar disk protrusion who experienced sudden, severe exacerbation of radicular pain during a VAX-D therapy session. Follow-up magnetic resonance imaging of the lumbar region showed marked enlargement of the disk protrusion, and urgent microdiskectomy was required. To our knowledge, this is the first reported complication of VAX-D therapy. This case shows that VAX-D therapy has the potential to cause sudden deterioration requiring urgent surgical intervention.

  11. Finite strain response of crimped fibers under uniaxial traction: An analytical approach applied to collagen

    Marino, Michele; Wriggers, Peter


    Composite materials reinforced by crimped fibers intervene in a number of advanced structural applications. Accordingly, constitutive equations describing their anisotropic behavior and explicitly accounting for fiber properties are needed for modeling and design purposes. To this aim, the finite strain response of crimped beams under uniaxial traction is herein addressed by obtaining analytical relationships based on the Principle of Virtual Works. The model is applied to collagen fibers in soft biological tissues, coupling geometric nonlinearities related to fiber crimp with material nonlinearities due to nanoscale mechanisms. Several numerical applications are presented, addressing the influence of geometric and material features. Available experimental data for tendons are reproduced, integrating the proposed approach within an optimization procedure for data fitting. The obtained results highlight the effectiveness of the proposed approach in correlating fibers structure with composite material mechanics.

  12. PM Motor Parametric Design Analyses for a Hybrid Electric Vehicle Traction Drive Application

    Staunton, R.H.


    The Department of Energy's (DOE) Office of FreedomCAR (Cooperative Automotive Research) and Vehicle Technologies office has a strong interest in making rapid progress in permanent magnet (PM) machine development. The DOE FreedomCAR program is directing various technology development projects that will advance the technology and hopefully lead to a near-term request for proposals (RFP) for a to-be-determined level of initial production. This aggressive approach is possible because the technology is clearly within reach and the approach is deemed essential, based on strong market demand, escalating fuel prices, and competitive considerations. In response, this study began parallel development paths that included a literature search/review, development and utilization of multiple parametric models, verification of the modeling methodology, development of an interior PM (IPM) machine baseline design, development of alternative machine baseline designs, and cost analyses for several candidate machines. This report summarizes the results of these activities as of September 2004. This report provides background and summary information for recent machine parametric studies and testing programs that demonstrate both the potential capabilities and technical limitations of brushless PM machines (axial gap and radial gap), the IPM machine, the surface-mount PM machines (interior or exterior rotor), induction machines, and switched-reluctance machines. The FreedomCAR program, while acknowledging the progress made by Oak Ridge National Laboratory (ORNL), Delphi, Delco-Remy International, and others in these programs, has redirected efforts toward a ''short path'' to a marketable and competitive PM motor for hybrid electric vehicle (HEV) traction applications. The program has developed a set of performance targets for the type of traction machine desired. The short-path approach entails a comprehensive design effort focusing on the IPM machine and meeting

  13. PM Motor Parametric Design Analyses for Hybrid Electric Vehicle Traction Drive Application: Interim Report

    Staunton, R.H.


    The Department of Energy's (DOE) Office of FreedomCAR (Cooperative Automotive Research) and Vehicle Technologies has a strong interest in making rapid progress in permanent magnet (PM) machine development. The program is directing various technology development projects that will advance the technology and lead to request for proposals (RFP) for manufacturer prototypes. This aggressive approach is possible because the technology is clearly within reach and the approach is deemed essential, based on strong market demand, escalating fuel prices, and competitive considerations. In response, this study began parallel development paths that included a literature search/review, development and utilization of multiple parametric models to determine the effects of design parameters, verification of the modeling methodology, development of an interior PM (IPM) machine baseline design, development of alternative machine baseline designs, and cost analyses for several candidate machines. This interim progress report summarizes the results of these activities as of June 2004. This report provides background and summary information for recent machine parametric studies and testing programs that demonstrate both the potential capabilities and technical limitations of brushless PM machines (axial gap and radial gap), the IPM machine, the surface-mount PM machines (interior or exterior rotor), induction machines, and switched reluctance machines. The FreedomCAR program, while acknowledging the progress made by Oak Ridge National Laboratory, Delphi, Delco-Remy International, and others in these programs, has redirected efforts toward a ''short path'' to a marketable and competitive PM motor for hybrid electric vehicle traction applications. The program has developed a set of performance targets for the type of traction machine desired. The short-path approach entails a comprehensive design effort focusing on the IPM machine and meeting the performance


    Kanwal Khan


    Full Text Available Background: Cervical radiculopathy, generally entitle as pinching of the nerves which causes severe shooting pain which mostly pass through the shoulder. Along with it causes muscle weakness and numbness into the arm and hand. In majority of the cases, cervical radiculopathy responds well to conservative mode of treatments which incorporate physical therapy with medical management. The aim of this study is to uncover the effective and evidence based conservative treatment of cervical radiculopathy. Method: Randomized controlled trial study conducted from January 2014 to December 2014. Participants were recruited from physiotherapy OPDs of tertiary care hospitals. A total number of, 100 subjects with a ratio of 50 men and 50 women were recruited between the ages of 25 and 55 years with unilateral cervical radiculopathy. Control group received combination of conventional AROM exercises and modalities including TENS and superficial thermotherapy as a treatment while experimental group received manual cervical traction and combination of conventional AROM exercises, modalities including TENS and superficial thermotherapy. For both groups, treatment was designed for two weeks (6 sessions/ week. Improvement in symptoms was assessed by evaluation of both groups on the basis of visual analogue scale (VAS. Results: After 2 weeks of treatment, patients with neck pain showed marked decreased in pain as compared with the control group (P<.001.For pre and post level a paired sample t-test was used and the results with p-value less than 0.05 were considered as significant. Mean difference of 0.94 (VAS with a significant p-value (P<0.01 was obtained shows the respective improvements in the numeric pain scale scores. Conclusion: Manual cervical traction when used with conventional AROM exercises and modalities were effective methods for decreasing pain in cervical radiculopathy. Recent literature supports such protocols involving multiple interventions. Results

  15. The efficacy of intermittent cervical traction in patents with chronic neck pain.

    Borman, Pinar; Keskin, Dilek; Ekici, Betul; Bodur, Hatice


    Previous studies about the usefulness of traction therapy have concluded with conflicting results. The aim of this study was to examine its efficacy in chronic neck pain. Forty-two patients with at least 6 weeks of nonspecific neck pain were selected for the study. Data about demographic characteristics including age, sex, body mass index, duration of cervical pain, working status, smoking status, and regular exercise were recorded. Each patient was randomly assigned to Group 1-receiving only standard physical therapy including hot pack, ultrasound therapy and exercise program and Group 2-treated with traction therapy in addition to standard physical therapy. The patients were reevaluated at the end of the therapy. The main outcome measures of the treatment were pain intensity by visual analog scale (VAS), disability by neck disability index (NDI), and quality of life assessed by Nottingham Health Profile (NHP). Twenty-four female and 18 male patients with mean age of 48.2+/-11.5 years and a mean disease duration of 4.3+/-2.9 years were included to the study. There were no differences between the groups in terms of age, sex, pain intensity, and scores of NHP and NDI at entry. There were 21 patients in both groups. Both groups improved significantly in pain intensity and the scores of NDI and physical subscles of NHP at the end of the therapies (ppain scores in both groups (pneck pain. We suggest the clinicians to consider this condition and to focus on exercise therapy in the management of patients suffering from this condition.

  16. PM Axial Flux Machine Design for Hybrid Traction Conception d’une machine à flux axial à aimants permanents pour la traction hybride

    de la Barrière O.


    Full Text Available the best ways in order to reduce fuel consumption for vehicles. It consists of associating an electric motor next to the classical thermal machine. In this embedded system, the efficiency and the torque per unit mass are very important. So it seems to be a good idea to use a permanent magnet synchronous machine, which is recognized for satisfying these two objectives. Since the allocated volume is rather flat, axial flux topologies are interesting. This paper’s goal is to propose an optimal first design method for such structures, given the allocated volume and the machine requirements. La traction hybride semble actuellement un des moyens les plus prometteurs pour réduire la consommation de carburant des véhicules. Ce procédé consiste à associer un moteur électrique au moteur thermique traditionnel. Pour une telle application embarquée, le rendement, ainsi que le couple massique, sont des critères de conception de première importance. Dans ce contexte, le recours à une machine synchrone à aimants permanents, reconnue pour satisfaire ces deux critères, semble être approprié. Vu que le volume alloué à la machine électrique est de forme discoïde, les topologies à flux axial semblent les plus intéressantes. L’objectif de cet article est de proposer une méthodologie de pré-dimensionnement de tels actionneurs, en ayant fixé au préalable le volume maximal permis ainsi que le cahier des charges de la machine.

  17. Probabilistic Analysis on Fault Tolerance of 3-Dimensional Mesh Networks%3-维Mesh网络容错性的概率分析研究

    王高才; 陈建二; 王国军; 陈松乔


    Mesh network is very popualr and important topological structure in parallel computing. In this paper,we focus on the fault tolerance of 3-dimensional mesh. We use the probability model to analyze the fault tolerance of mesh. To simplify our analysis, we assume the failure probability of each node is independent. We partition a 3-dimensional mesh into smaller submeshes and compute the probability with which each submesh satisfies the condition we define. If each submesh satisfies the condition, then the whole mesh is connected. We then compute the probability that a 3-dimensional mesh is connected assuming each node has a failure probability p. We use mathematical methods to derive a relationship between network node failure probability and network connectivity probability. Our simulations show that 3-dimensional mesh networks can remain connected with very high probability in practice. For example, the paper formally proves that when the network node failure probability is bounded by 0.05%, 3-dimensional mesh network of more than two hundred thousand nodes remain connected with probability larger than 99%. Theoretical and experimental results show that our method is powderful technique to calculate the lower bound of the connectivity probability of mesh network.

  18. Three-directed traction for extention type of supracondylar fracture of humerus in children%儿童伸直型肱骨髁上骨折的三向牵引治疗

    张敬东; 彭明惺; 索朗; 刘利君; 韦福康; 刘敏; 罗启成


    Objective To evaluate efficacy of three-directed traction ( olecranon skeletal traction on the horizontal, forearm traction on the upwards and humerus traction downwards) for extention type of supracondylar fractures humerus in children. Methods The efficacy and treatment of three-directed traction on 25 cases of extention type of supracondylar fractures of humerus in children were analyzed retrospectively. Results The efficacy was satisfactory in the time of follow-up; All displacements of fractures were be corrected gradually and none replacement in three-directed traction therapy time; Elbow joint function were fine after callus growth through 2 weeks of plaster fixation. Conclusion The three-directed traction is a good method for treatment in extention type of supracondylar fractures of humerus in children. This method is simpleness, credibility and reduction stabilization.

  19. A Novel Approach to Measure the Forces Exerted by Cells on Elastic Substrates

    Guan, E.; Muralidhar, Sravanesh; Ghosh, Kaustabh; Clark, Richard; Rafailovich, Miriam; Sokolov, Jonathan


    We have observed that the cytoskeleton of a cell is very sensitive to the mechanical rigidty of the substrate. Furthermore we have found that this rearrangement is correlated to the attempt by the cell to match its modulus, as closely as possible, to that of the substrate. We postulate that the driving force for this phenomenon is the minimization of the large forces exerted at the contact line by the substrate on the cell. It is therefore important to be able to measure both the modulus of the cell as well as the surface forces on the same sample. In this study, we introduced a novel approach to measure the traction force. Instead of just measuring the 2-dimensional displacement of patterned features on a surface [1], the three-dimensional displacement field inside the sample was measured with the help of z-scan function of confocal microscope. Three-dimensional strain at the substrate surface was then calculated with numerical differentiation. Knowing the shear modulus of substrate, the traction force was computed simply by the application of Hooke's law, which is a simple linear relation. In this method the Fredholm integral can be avoided and the force locations can be determined without specific staining of the adherins once the force field is obtained. [1] Karen Beningo and Yu-Li Wang, TRENDS in Cell Biology, Vol.12 No.2 Feb 2002, pp79-84.

  20. The Use of Biofiltration Technology and 3-dimensional Cubical Bamboo Shelter for Nursery Phase Productivity Improvement of Giant Freshwater Prawn

    Gede Suantika


    Full Text Available This experiment aimed to know the effect of nitrifying bacteria and Chlorellasp. addition and different number of 3-dimensional cubical bamboo shelter in enhancing growth performance of Giant Freshwater Prawn (Macrobrachium rosenbergii de Man during nursery phase in indoor system. During28 days of culture, treatment II (4 shelters addition~40% culture volume occupation resulted in better prawn growth and culture performance compared to control (no shelter addition (p<0,05. At the end of experiment, treatment II shown the highest biomass, SGR, mean body weight and length of the prawn with (1.96+0.05 g.cage-1,, (2.18 +0,89 g and (6.50 +0.91 cm, respectively. However, the results were not significantly different compared to treatment I (2 shelters addition~20%culture volume occupation. Survival rate the two treatments (treatment I="90"%, and treatment II="92"% was significantly higher compared to control (78%. During the experiments, increase of ammonium concentration and nitrate can be controlled and maintained by addition of nitrifying bacteria and microalgae which can keep the microbial loop between ammonium reduction by bacteria and nitrate uptake by microalgae in balance. Addition of nitrifying bacteria and microalgae and also availability of 40% bamboo shelter occupation in the culture can enhance prawn culture productivity.

  1. Quantitative analysis of 3-dimensional rootarchitecture based on image reconstruction and itsapplication to research on phosphorus uptake in soybean

    ZHU Tonglin; FANG Suqin; LI Zhiyuan; LIU Yutao; LIAO Hong; YAN Xiaolong


    Quantification of 3-dimensional (3-D) plant root architecture is one of the most important approaches to investigating plant root growth and its function in nutrient acquisition and utilization. However, no effective methods have been reported hitherto to quantify 3-D root architecture parameters, making it difficult to further study the 3-D characteristics of the root system and its function. In the present study, we created a rapid algorithm to reconstruct 3-D root system images based on the basic structural features of such linear objects as roots, using 2-D root images taken by digital CCD cameras at multi- viewing angles. This method is very effective in the reconstruction of plant root system images, thus enabling us to obtain the digital model of 3-D root architecture and its 3-D skeleton, based on which some major root architecture parameters can be calculated. Using this method, we were able to acquire 3-D parameters of soybean root architecture whose root diameter was more than 0.3 mm, including tap root length, total root length, average basal root angle, ratio of root width to root depth, percentage distribution of root length in different layers and root distribution in different 3-D regions of the growth medium. We also quantitatively analyzed the relationship between different root architecture parame-ters and such plant nutrition parameters as soybean biomass and phosphorus (P) uptake. Our study may provide a new tool in studying the growth and nutritional functions of plant root systems.

  2. A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles.

    Hoelting, Lisa; Scheinhardt, Benjamin; Bondarenko, Olesja; Schildknecht, Stefan; Kapitza, Marion; Tanavde, Vivek; Tan, Betty; Lee, Qian Yi; Mecking, Stefan; Leist, Marcel; Kadereit, Suzanne


    Nanoparticles (NPs) have been shown to accumulate in organs, cross the blood-brain barrier and placenta, and have the potential to elicit developmental neurotoxicity (DNT). Here, we developed a human embryonic stem cell (hESC)-derived 3-dimensional (3-D) in vitro model that allows for testing of potential developmental neurotoxicants. Early central nervous system PAX6(+) precursor cells were generated from hESCs and differentiated further within 3-D structures. The 3-D model was characterized for neural marker expression revealing robust differentiation toward neuronal precursor cells, and gene expression profiling suggested a predominantly forebrain-like development. Altered neural gene expression due to exposure to non-cytotoxic concentrations of the known developmental neurotoxicant, methylmercury, indicated that the 3-D model could detect DNT. To test for specific toxicity of NPs, chemically inert polyethylene NPs (PE-NPs) were chosen. They penetrated deep into the 3-D structures and impacted gene expression at non-cytotoxic concentrations. NOTCH pathway genes such as HES5 and NOTCH1 were reduced in expression, as well as downstream neuronal precursor genes such as NEUROD1 and ASCL1. FOXG1, a patterning marker, was also reduced. As loss of function of these genes results in severe nervous system impairments in mice, our data suggest that the 3-D hESC-derived model could be used to test for Nano-DNT.

  3. A 3-Dimensional study of the Local Environment of Bright IRAS Galaxies: The AGN/Starburst connection

    Koulouridis, E; Plionis, M; Krongold, Y; Dultzin-Hacyan, D; Koulouridis, Elias; Chavushyan, Vahram; Plionis, Manolis; Krongold, Yair; Dultzin-Hacyan, Deborah


    We present a 3-dimensional study of the local ($\\leq 100 h^{-1}$ kpc) and the large scale ($\\leq$ 1 $h^{-1}$ Mpc) environment of Bright IRAS Galaxies (BIRGs). For this purpose we use 87 BIRGs located at high galactic latitudes (with 0.008$\\leq z \\leq$0.018) as well as a control sample of non-active galaxies having the same morphological, redshift and diameter size distributions as the corresponding BIRG sample. Using the Center for Astrophysics (CfA2) and Southern Sky Redshift Survey (SSRS) galaxy catalogues ($m_b\\lesssim 15.5$)as well as our own spectroscopic observations ($m_b\\lesssim19.0$) for a subsample of the original BIRG sample, we find that the fraction of BIRGs with a close neighbor is significantly higher than that of their control sample. Comparing with a related analysis of Sy1 and Sy2 galaxies of Koulouridis et al. (2006) we find that BIRGs have a similar environment as Sy2s, although the fraction of BIRGs with a bright close neighbor is even higher than that of Sy2 galaxies. An additional analy...

  4. Heating-Rate-Triggered Carbon-Nanotube-based 3-Dimensional Conducting Networks for a Highly Sensitive Noncontact Sensing Device

    Tai, Yanlong


    Recently, flexible and transparent conductive films (TCFs) are drawing more attention for their central role in future applications of flexible electronics. Here, we report the controllable fabrication of TCFs for moisture-sensing applications based on heating-rate-triggered, 3-dimensional porous conducting networks through drop casting lithography of single-walled carbon nanotube (SWCNT)/poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT:PSS) ink. How ink formula and baking conditions influence the self-assembled microstructure of the TCFs is discussed. The sensor presents high-performance properties, including a reasonable sheet resistance (2.1 kohm/sq), a high visible-range transmittance (>69%, PET = 90%), and good stability when subjected to cyclic loading (>1000 cycles, better than indium tin oxide film) during processing, when formulation parameters are well optimized (weight ratio of SWCNT to PEDOT:PSS: 1:0.5, SWCNT concentration: 0.3 mg/ml, and heating rate: 36 °C/minute). Moreover, the benefits of these kinds of TCFs were verified through a fully transparent, highly sensitive, rapid response, noncontact moisture-sensing device (5 × 5 sensing pixels).

  5. Image-driven cardiac left ventricle segmentation for the evaluation of multiview fused real-time 3-dimensional echocardiography images.

    Rajpoot, Kashif; Noble, J Alison; Grau, Vicente; Szmigielski, Cezary; Becher, Harald


    Real-time 3-dimensional echocardiography (RT3DE) permits the acquisition and visualization of the beating heart in 3D. Despite a number of efforts to automate the left ventricle (LV) delineation from RT3DE images, this remains a challenging problem due to the poor nature of the acquired images usually containing missing anatomical information and high speckle noise. Recently, there have been efforts to improve image quality and anatomical definition by acquiring multiple single-view RT3DE images with small probe movements and fusing them together after alignment. In this work, we evaluate the quality of the multiview fused images using an image-driven semiautomatic LV segmentation method. The segmentation method is based on an edge-driven level set framework, where the edges are extracted using a local-phase inspired feature detector for low-contrast echocardiography boundaries. This totally image-driven segmentation method is applied for the evaluation of end-diastolic (ED) and end-systolic (ES) single-view and multiview fused images. Experiments were conducted on 17 cases and the results show that multiview fused images have better image segmentation quality, but large failures were observed on ED (88.2%) and ES (58.8%) single-view images.

  6. The Accuracy of Prostate Cancer Localization Diagnosed on Transrectal Ultrasound-Guided Biopsy Compared to 3-Dimensional Transperineal Approach

    Kevin Krughoff


    Full Text Available Background. Prostate cancer is often understaged following 12-core transrectal ultrasound- (TRUS- guided biopsies. Our goal is to understand where cancers are typically missed by this method. Methods. Transperineal 3-dimensional mapping biopsy (3DMB provides a more accurate depiction of disease status than transrectal ultrasound- (TRUS- guided biopsy. We compared 3DMB findings in men with prior TRUS-guided biopsies to determine grade and location of missed cancer. Results were evaluated for 161 men with low-risk organ confined prostate cancer. Results. The number of cancer-positive biopsy zones per patient with TRUS was 1.38 ± 1.21 compared to 3.33 ± 4.06 with 3DMB, with most newly discovered cancers originating from the middle lobe and apex. Approximately half of all newly discovered cancerous zones resulted from anterior 3DMB sampling. Gleason upgrade was recognized in 56 patients using 3DMB. When both biopsy methods found positive cores in a given zone, Gleason upgrades occurred most frequently in the middle left and right zones. TRUS cancer-positive zones not confirmed by 3DMB were most often the basal zones. Conclusion. Most cancer upgrades and cancers missed from TRUS biopsy originated in the middle left zone of the prostate, specifically in anterior regions. Anterior sampling may lead to more accurate diagnosis and appropriate followup.

  7. Cognitive functions and stereopsis in patients with Parkinson's disease and Alzheimer's disease using 3-dimensional television: a case controlled trial.

    Chan-Nyoung Lee

    Full Text Available Stereopsis or depth perception is an awareness of the distances of objects from the observer, and binocular disparity is a necessary component of recognizing objects through stereopsis. In the past studies, patients with neurodegenerative disease (Alzheimer dementia, AD; Parkinson's disease IPD have problems of stereopsis but they did not have actual stimulation of stereopsis. Therefore in this study, we used a 3-dimensional (3D movie on 3D television (TV for actual stereopsis stimulation. We propose research through analyzing differences between the three groups (AD, IPD, and Controls, and identified relations between the results from the Titmus Stereo Fly Test, and the 3D TV test. The study also looked into factors that affect the 3D TV test. Before allowing the patients to watch TV, we examined Titmus stereo Fly Test and cognitive test. We used the 3D version of a movie, of 17 minutes 1 second duration, and carried out a questionnaire about stereopsis. The scores of the stereopsis questionnaire were decreased in AD patients, compared with in IPD and controls, although they did not have any difference of Titmus Stereo Fly Test scores. In IPD patients, cognitive function (Montreal cognitive assessment, MoCA scores were correlated with the scores of the stereopsis questionnaire. We could conclude that Titmus fly test could not distinguish between the three groups and cognitive dysfunction contributes to actual stereopsis perception in IPD patients. Therefore the 3D TV test of AD and IPD patients was more effective than Titmus fly test.

  8. Metal organic framework derived magnetically separable 3-dimensional hierarchical Ni@C nanocomposites: Synthesis and adsorption properties

    Song, Yixuan; Qiang, Tingting; Ye, Ming; Ma, Qiuyang; Fang, Zhen


    Design an effective absorbent that has high surface area, and perfect recyclable is imperative for pollution elimination. Herein, we report a facile two-step strategy to fabricate magnetically separable 3-dimensional (3D) hierarchical carbon-coated nickel (Ni@C) nanocomposites by calcinating nickel based metal organic framework (Ni3(OH)2(C8H4O4)2(H2O)4). SEM and TEM images illuminate that the nanocomposites were constructed by 8 nm nickel nanoparticle encapsulated in 3D flake like carbon. The specific surface area of the obtained nanocomposites is up to 120.38 m2 g-1. Room temperature magnetic measurement indicates the nanocomposites show soft magnetism property, which endows the nanocomposites with an ideal fast magnetic separable property. The maximum adsorption capacity of the nanocomposites for rhodamine B is 84.5 mg g-1. Furthermore, the nanocomposites also exhibit a high adsorption capacity for heavy metal ions. The adsorbent can be very easily separated from the solution by using a common magnet without exterior energy. The as-prepared Ni@C nanocomposites can apply in waste water treatment on a large-scale as a new adsorbent with high efficiency and excellent recyclability.

  9. Arrays of ZnO nanocolumns for 3-dimensional very thin amorphous and microcrystalline silicon solar cells

    Neykova, Neda, E-mail: [Institute of Physics, Academy of Sciences of the Czech Republic, Cukrovarnicka 10, 16253 Prague 6 (Czech Republic); Czech Technical University in Prague, Faculty of Nuclear Sciences and Physical Engineering Trojanova 13, 120 00 Prague 2 (Czech Republic); Hruska, Karel; Holovsky, Jakub; Remes, Zdenek; Vanecek, Milan [Institute of Physics, Academy of Sciences of the Czech Republic, Cukrovarnicka 10, 16253 Prague 6 (Czech Republic)


    We report on the hydrothermal growth of high quality arrays of single crystalline zinc oxide (ZnO) nanocolumns, oriented perpendicularly to the transparent conductive oxide substrate. In order to obtain precisely defined spacing and arrangement of ZnO nanocolumns over an area up to 0.5 cm{sup 2}, we used electron beam lithography. Vertically aligned ZnO (multicrystalline or single crystals) nanocolumns were grown in an aqueous solution of zinc nitrate hexahydrate and hexamethylenetetramine at 95 °C, with a growth rate 0.5 ÷ 1 μm/h. The morphology of the nanostructures was visualized by scanning electron microscopy. Such nanostructured ZnO films were used as a substrate for the recently developed 3-dimensional thin film silicon (amorphous, microcrystalline) solar cell, with a high efficiency potential. The photoelectrical and optical properties of the ZnO nanocolumns and the silicon absorber layers of these type nanostructured solar cells were investigated in details. - Highlights: • Vertically-oriented ZnO nanocolumns were grown by hydrothermal method. • The ZnO nanocolumns were grown over an area of 0.5 cm{sup 2}. • For precise arrangement of the ZnO nanocolumns electron beam lithography was used. • We report on 3-D design of nanostructured solar cell. • Optical thickness of nanostructured cell was three times higher compared to flat cell.

  10. Morphological analysis and preoperative simulation of a double-chambered right ventricle using 3-dimensional printing technology.

    Shirakawa, Takashi; Koyama, Yasushi; Mizoguchi, Hiroki; Yoshitatsu, Masao


    We present a case of a double-chambered right ventricle in adulthood, in which we tried a detailed morphological assessment and preoperative simulation using 3-dimensional (3D) heart models for improved surgical planning. Polygonal object data for the heart were constructed from computed tomography images of this patient, and transferred to a desktop 3D printer to print out models in actual size. Medical staff completed all of the work processes. Because the 3D heart models were examined by hand, observed from various viewpoints and measured by callipers with ease, we were able to create an image of the complete form of the heart. The anatomical structure of an anomalous bundle was clearly observed, and surgical approaches to the lesion were simulated accurately. During surgery, we used an incision on the pulmonary infundibulum and resected three muscular components of the stenosis. The similarity between the models and the actual heart was excellent. As a result, the operation for this rare defect was performed safely and successfully. We concluded that the custom-made model was useful for morphological analysis and preoperative simulation.

  11. Traction-transport components integrated in fuel cells; running constraints, lifetime, reliability; Les composants traction-transport integres dans les systemes PAC; contraintes de mission, duree de vie, fiabilite

    Coquery, G. [Institut National de Recherche sur les transports et leur Securite, INRETS LTN, 94 - Arcueil (France)


    The future systems 'fuel cell' on-board in transport vehicles 'SPACT' will be optimized by the control of energy fluxes: of generation, of traction, of recovery to braking and of stored energy. The aim is to reach the level required for the user in terms of reliability, availability, maintainability and safety for a transport vehicle answering to economical and environmental criteria. Despite the obvious necessity of the research and industrialization studies on the 'SPACT' technologies, the current technological advances on the integration of the electronics for traction and the energy storage by super-capacitors and batteries are also determining factors for the industrialization of these hybrid systems. The proposed study presents the constraints of the transport applications, lifetime and reliability, the technologies of the power integration and the future developments of these new components for the transport sector. (O.M.)

  12. Strong Force

    Without the strong force, there could be no life. The carbon in living matter is synthesised in stars via the strong force. Lighter atomic nuclei become bound together in a process called nuclear fusion. A minor change in this interaction would make life impossible. As its name suggests, the strong force is the most powerful of the 4 forces, yet its sphere of influence is limited to within the atomic nucleus. Indeed it is the strong force that holds together the quarks inside the positively charged protons. Without this glue, the quarks would fly apart repulsed by electromagnetism. In fact, it is impossible to separate 2 quarks : so much energy is needed, that a second pair of quarks is produced. Text for the interactive: Can you pull apart the quarks inside a proton?

  13. Image Quality of the 3 Dimensional Phase-Contrast Technique in an Intracranial Magnetic Resonance Angiography with Artifacts Caused by Orthodontic Devices: A Comparison with 3 Dimensional Time-of-Flight Technique

    Kang, Seong Jin; Kim, Young Soo; Hong, Hyun Sook [Dept. of Radiology, Soonchunhyang University College of Medicine, Bucheon (Korea, Republic of); Kim, Dong Hun [Dept. of Radiology, Chosun University School of Medicine, Kwangju (Korea, Republic of)


    To evaluate the degree of image distortion caused by orthodontic devices during a intracranial magnetic resonance angiography (MRA), and to determine the effectiveness of the 3 dimensional phase-contrast (3D PC). Subjects were divided into group A (n = 20) wearing a home-made orthodontic device, and group B (n = 10) with an actual orthodontic device. A 3.0T MR scanner was used, applying 3D time-of-flight (TOF) and 3D PC. Two board-certified radiologists evaluated images independently based on a four point scale classifying segments of the circle of Willis. Magnetic susceptibility variations and contrast-to-noise ratio (CNR) on maximum intensity projection images were measured. In group A, scores of the 3D TOF and 3D PC were 2.84 {+-} 0.1 vs. 2.88 {+-} 0.1 (before) and 1.8 {+-} 0.4 vs 2.83 {+-} 0.1 (after wearing device), respectively. In group B, the scores of 3D TOF and 3D PC were 1.86 {+-} 0.43 and 2.81 {+-} 0.15 (p = 0.005), respectively. Magnetic susceptibility variations showed meaningful results after wearing the device (p = 0.0001). CNRs of the 3D PC before and after wearing device were 142.9 {+-} 6.6 vs. 140.8 {+-} 7.2 (p = 0.7507), respectively. In the 3D TOF, CNRs were 324.8 {+-} 25.4 vs. 466.3 {+-} 41.7 (p = 0.0001). The 3D PC may be a solution method for distorted images by magnetic susceptibility in the intracranial MRA compared with 3D TOF.

  14. The Effects of Stretching with Lumbar Traction on VAS and Oswestry Scales of Patients with Lumbar 4–5 Herniated Intervertebral Disc

    Yang, Hae-sun; Yoo, Won-gyu


    [Purpose] This study investigated the effect of stretching with lumbar traction on VAS and Oswestry scale scores of lumbar 4–5 herniated intervertebral disc (HIVD) patients. [Subjects] We recruited 20 lumbar 4–5 HIVD patients. [Methods] We performed stretching with lumbar traction for lumbar 4–5 HIVD patients during 4 weeks. The VAS and Oswestry scales were measured before and 4 weeks after the intervention. [Results] The results showed a significant decrease in VAS scale scores for stretchin...

  15. Influences of spinal decompression therapy and general traction therapy on the pain, disability, and straight leg raising of patients with intervertebral disc herniation

    Choi, Jioun; Lee, Sangyong; Hwangbo, Gak


    [Purpose] The purpose of this study was to identify how spinal decompression therapy and general traction therapy influence the pain, disability, and straight leg raise (SLR) ability of patients with intervertebral disc herniation. [Subjects] The subjects were 30 patients with chronic lumbar pain who were divided into a spinal decompression therapy group (SDTG, n=15), and a general traction therapy group (GTTG, n=15). [Methods] The SDTG used a spinal decompression device, and the GTTG used a ...

  16. A clinical prediction rule for classifying patients with low back pain who demonstrate short-term improvement with mechanical lumbar traction

    Cai, Congcong; Pua, Yong Hao; Lim, Kian Chong


    The objective of the study was to develop a clinical prediction rule for identifying patients with low back pain, who improved with mechanical lumbar traction. A prospective, cohort study was conducted in a physiotherapy clinic at a local hospital. Patients with low back pain, referred to physiotherapy were included in the study. The intervention was a standardized mechanical lumbar traction program, which comprised three sessions provided within 9 days. Patient demographic information, stand...

  17. Identification of Magnetizing Inrush and Internal Short-Circuit Fault Current in V/x-Type Traction Transformer

    Y. H. Li


    Full Text Available This paper deals with the fault diagnosis methodology for the V/x-type traction transformer in railway passenger-dedicated lines. A kind of the protection methodology to combine empirical mode decomposition (EMD, energy weight, and information entropy is proposed. This method can sensitively reflect the dynamic information changes of traction transformer differential current, so it can not only effectively identify internal short-circuit fault current from magnetizing inrush but also better identify fault current accompanied with magnetizing inrush. In this method, the differential current is decomposed by EMD and the energy weight of each intrinsic mode function (IMF is calculated, and the feature vector of the fault pattern recognition is obtained by constructing IMF energy entropy. The field-measured data illustrate that the new method not only has the advantages of high sensitivity, faster identification speed, and clear concept but also is available for the diagnosis of the complicated dynamic system.


    Zailiang Li; Cheng Wang


    Although boundary displacement and traction are independent field variables in boundary conditions of an elasticity problem at a non-singular boundary point,there exist definite relations of singularity intensities between boundary displacement derivatives and tractions at a singular boundary point.The analytical forms of the relations at a singular smooth point for 2D isotropic elastic problems have been established in this work.By using the relations,positions of the singular boundary points and the corresponding singularity intensities of the unknown boundary field variables can be determined a priori.Therefore,more appropriate shape functions of the unknown boundary field variables in singular elements can be constructed.A numerical example shows that the accuracy of the BEM analysis using the developed theory is greatly increased.

  19. 高原电力机车IGBT主变流器%IGBT Traction Convertor of Electric Locomotives for Altiplano

    范荣辉; 秦方方; 郭君博; 李华


    Main technic parameters, power circuit and it's converter module characteristics of IGBT traction convenor of electric locomotives for altiplano were introduced. The adaptability design for altiplano was presented such as the working principle of heater, and so on. The traction converter was validated satisfying altiplano locomotive applying requirement by the test data.%介绍了应用于高原环境下的电力机车IGBT主变流器的主要技术参数、主电路及其变流器模块特点,并叙述了主变流器高原环境适应性相关设计,如内置加热器的工作原理等.型式试验数据表明,该变流器相关技术参数能够满足高原电力机车应用要求.

  20. Weak Force

    Without the weak force, the sun wouldn't shine. The weak force causes beta decay, a form of radioactivity that triggers nuclear fusion in the heart of the sun. The weak force is unlike other forces: it is characterised by disintegration. In beta decay, a down quark transforms into an up quark and an electron is emitted. Some materials are more radioactive than others because the delicate balance between the strong force and the weak force varies depending on the number of particles in the atomic nucleus. We live in the midst of a natural radioactive background that varies from region to region. For example, in Cornwall where there is a lot of granite, levels of background radiation are much higher than in the Geneva region. Text for the interactive: Move the Geiger counter to find out which samples are radioactive - you may be surprised. It is the weak force that is responsible for the Beta radioactivity here. The electrons emitted do not cross the plastic cover. Why do you think there is some detected radioa...

  1. Properties and toxicological effects of particles from the interaction between tyres, road pavement and winter traction material

    Gustafsson, Mats [Swedish National Road and Transport Research Institute (VTI), SE-581 95 Linkoeping (Sweden)], E-mail:; Blomqvist, Goeran [Swedish National Road and Transport Research Institute (VTI), SE-581 95 Linkoeping (Sweden); Gudmundsson, Anders; Dahl, Andreas [Division of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, P.O. Box 118, SE-221 00 Lund (Sweden); Swietlicki, Erik [Division of Nuclear Physics, Department of Physics, Lund University, P.O. Box 118, SE-221 00 Lund (Sweden); Bohgard, Mats [Division of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, P.O. Box 118, SE-221 00 Lund (Sweden); Lindbom, John; Ljungman, Anders [Faculty of Health Sciences, Department of Molecular and Clinical Medicine, Division of Occupational and Environmental Medicine, SE-581 85 Linkoeping (Sweden)


    In regions where studded tyres and traction material are used during winter, e.g. the Nordic countries, northern part of USA, Canada, and Japan, mechanically generated particles from traffic are the main reason for high particle mass concentrations in busy street and road environments. In many Nordic municipalities the European environmental quality standard for inhalable particles (PM{sub 10}) is exceeded due to these particles. In this study, particles from the wear of studded and studless friction tyres on two pavements and traction sanding were generated using a road simulator. The particles were characterized using particle sizers, Particle Induced X-Ray Emission Analysis and electron microscopy. Cell studies were conducted on particles sampled from the tests with studded tyres and compared with street environment, diesel exhaust and subway PM{sub 10}, respectively. The results show that in the road simulator, where resuspension is minimized, studded tyres produce tens of times more particles than friction tyres. Chemical analysis of the sampled particles shows that the generated wear particles consist almost entirely of minerals from the pavement stone material, but also that Sulfur is enriched for the submicron particles and that Zink is enriched for friction tyres for all particles sizes. The chemical data can be used for source identification and apportionment in urban aerosol studies. A mode of ultra-fine particles was also present and is hypothesised to originate in the tyres. Further, traction material properties affect PM{sub 10} emission. The inflammatory potential of the particles from wear of pavements seems to depend on type of pavement and can be at least as potent as diesel exhaust particles. The results imply that there is a need and a good potential to reduce particle emission from pavement wear and winter time road and street operation by adjusting both studded tyre use as well as pavement and traction material properties.

  2. Effect of joint traction on functional improvement and quality of life in patients with severe knee osteoarthritis

    Sedigheh Sadat Naeimee; Abbas Rahimi; Mehdi Rezaee; Alireza Akbarzadeh Baghban; Khosro Khademi Kalantari; ُSomayeh Mahmoudi Aghdam


    Background and aim: Osteoarthritis (OA) is the most prevalent joint disease in adults around the world and its incidence rises with age. Patients with severe knee osteoarthritis often complain of pain and severe functional disability. Most of conservative treatments used in this group of patients induce poor improvements. This study evaluated the effect of joint traction on quality of life of patients with severe knee osteoarthritis.Materials and Methods: In this clinical trial study, forty f...

  3. Measuring of Traction and Speed Characteristics as Well as of Fuel Economy of a Car in Road Conditions

    Krivtsov, Sergey N.; Syrbakov, Andrey P.; Korchuganova, Marina A.


    This article is devoted to the identification of traction and speed characteristics as well as of fuel economy of motor vehicles in road conditions. Among common variants of measuring of the above stated values, the preference was given to the immediate gaining of factors by means of a computer-aided measuring system. There is a theoretical justification given to the suggested approach as well as methods and results allowing to provide a practically sufficient solution accuracy of the problem.

  4. Lumbar extension exercises in conjunction with mechanical traction for the management of a patient with a lumbar herniated disc.

    Gagne, Allison R; Hasson, Scott M


    Low back pain resulting from lumbar disc herniation is a common reason for referral for physical therapy. There is no evidence to support the management of lumbar disc herniation and derangement using mechanical traction combined with lumbar extension exercises. Therefore, the purpose of this case report was to describe and discuss the use of mechanical traction in conjunction with lumbar extension exercises for a patient with a lumbar herniated disc. The patient was a 49-year-old male referred to physical therapy with a medical diagnosis of a lumbar herniated disc at L5-S1 with compression of the L5 nerve root confirmed by MRI. The patient's chief complaint was pain over the left lumbosacral and central lumbar region with radiating pain into the left buttock accompanied by numbness and tingling in the left lower leg and foot. The patient was seen for a total of 14 visits. The first 5 days (2 weeks) of therapy consisted of lumbar extension exercises. For the following nine visits (over a 3-week period), mechanical traction was added as an adjunct to the extension exercises. Outcome measures included the Oswestry Disability Questionnaire, Back Pain Function Scale (BPFS), and the Numeric Pain Rating Scale (NPRS). Results from initial evaluation to discharge (Oswestry: 36% to 0%; BPFS: 33/60 to 57/60; NPRS: 7/10 to 0/10) demonstrated that the patient no longer experienced low back pain and improved in terms of functional status and pain-related disability. The patient no longer complained of numbness and tingling in the left lower extremity and the goals for the patient had been attained. The data from this case report suggests lumbar extension exercises in conjunction with mechanical traction facilitated the patient's improvement in pain and return to prior level of function.

  5. Theoretical aspects and methods of the parameters identification of the electric traction system devices. the instantaneous powers method; series connection of elements

    T.M. Mishchenko


    Full Text Available Introduction: By means of the mathematical or computer (imitating modeling the emergency, especially stochastic, transient electromagnetic and / or electro energetic processes in the electric traction system of the alternating current should be investigated. It allows expanding the research opportunities, as well as simplifying and reducing the actual testing, because it permits the wide variation of values and parameters reality of the elements of electric power circuits in the traction system without considerable material costs. Purpose: For this purpose the mathematical model of the nonlinear dynamical system "traction substation – electric traction network – electric rolling stock» as a passive two-terminal network with the given input voltage and input current is proposed. Task: The identification problem of the device under study, therefore the two-terminal network, is the determination electrical parameters (active resistance to inductance and capacity of the passive elements, which substitute the two-terminal network. The scheme of its substitution looks like the series connection of passive elements. Methodology: The method of solving this problem for the passive two-terminal network in the traction mode with alternating, nonsinusoidal, deterministic periodic input voltage and input current is proposed. The calculations are executed for the electric locomotives DS3 and 2ES5K. Results: The results for the parameters can be applied in the further calculations of the more complex electric traction systems of the alternating current.

  6. Construction of 3-dimensional ZnO-nanoflower structures for high quantum and photocurrent efficiency in dye sensitized solar cell

    Kilic, Bayram, E-mail: [Yalova University, Department of Energy Systems Engineering, Faculty of Engineering, 77100 Yalova (Turkey); Günes, Taylan; Besirli, Ilknur; Sezginer, Merve [Yalova University, Department of Energy Systems Engineering, Faculty of Engineering, 77100 Yalova (Turkey); Tuzemen, Sebahattin [Department of Physics, Faculty of Science, Atatürk University, Erzurum 25240 (Turkey)


    Graphical abstract: - Highlights: • The structural and optical characterizations of ZnO nanoflowers were carried out on ITO by hydrothermal method. • Dye sensitized solar cell based ZnO nanoflowers were constructed on substrate. • The surface morphology effect on quantum efficiency and solar conversion efficiency were investigated. - Abstract: 3-dimensional ZnO nanoflower were obtained on FTO (F:SnO{sub 2}) substrate by hydrothermal method in order to produce high efficiency dye sensitized solar cells (DSSCs). We showed that nanoflowers structures have nanoscale branches that stretch to fill gaps on the substrate and these branches of nano-leaves provide both a larger surface area and a direct pathway for electron transport along the channels. It was found that the solar conversion efficiency and quantum efficiency (QE) or incident photon to current conversion efficiencies (IPCE) is highly dependent on nanoflower surface due to high electron injection process. The highest solar conversion efficiency of 5.119 and QE of 60% was obtained using ZnO nanoflowers/N719 dye/I{sup −}/I{sup −}{sub 3} electrolyte. In this study, three dimensional (3D)-nanoflower and one dimensional (1D)-nanowires ZnO nanostructures were also compared against each other in respect to solar conversion efficiency and QE measurements. In the case of the 1D-ZnO nanowire conversion efficiency (η) of 2.222% and IPCE 47% were obtained under an illumination of 100 mW/cm{sup 2}. It was confirmed that the performance of the 3D-nanoflowers was better than about 50% that of the 1D-nanowire dye-sensitized solar cells.

  7. Accuracy Evaluation of a 3-Dimensional Surface Imaging System for Guidance in Deep-Inspiration Breath-Hold Radiation Therapy

    Alderliesten, Tanja; Sonke, Jan-Jakob; Betgen, Anja; Honnef, Joeri; Vliet-Vroegindeweij, Corine van [Department of Radiation Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands); Remeijer, Peter, E-mail: [Department of Radiation Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands)


    Purpose: To investigate the applicability of 3-dimensional (3D) surface imaging for image guidance in deep-inspiration breath-hold radiation therapy (DIBH-RT) for patients with left-sided breast cancer. For this purpose, setup data based on captured 3D surfaces was compared with setup data based on cone beam computed tomography (CBCT). Methods and Materials: Twenty patients treated with DIBH-RT after breast-conserving surgery (BCS) were included. Before the start of treatment, each patient underwent a breath-hold CT scan for planning purposes. During treatment, dose delivery was preceded by setup verification using CBCT of the left breast. 3D surfaces were captured by a surface imaging system concurrently with the CBCT scan. Retrospectively, surface registrations were performed for CBCT to CT and for a captured 3D surface to CT. The resulting setup errors were compared with linear regression analysis. For the differences between setup errors, group mean, systematic error, random error, and 95% limits of agreement were calculated. Furthermore, receiver operating characteristic (ROC) analysis was performed. Results: Good correlation between setup errors was found: R{sup 2}=0.70, 0.90, 0.82 in left-right, craniocaudal, and anterior-posterior directions, respectively. Systematic errors were {<=}0.17 cm in all directions. Random errors were {<=}0.15 cm. The limits of agreement were -0.34-0.48, -0.42-0.39, and -0.52-0.23 cm in left-right, craniocaudal, and anterior-posterior directions, respectively. ROC analysis showed that a threshold between 0.4 and 0.8 cm corresponds to promising true positive rates (0.78-0.95) and false positive rates (0.12-0.28). Conclusions: The results support the application of 3D surface imaging for image guidance in DIBH-RT after BCS.

  8. Chondroregulatory action of prolactin on proliferation and differentiation of mouse chondrogenic ATDC5 cells in 3-dimensional micromass cultures

    Seriwatanachai, Dutmanee [Center of Calcium and Bone Research (COCAB), Faculty of Science, Mahidol University, Bangkok (Thailand); Krishnamra, Nateetip [Center of Calcium and Bone Research (COCAB), Faculty of Science, Mahidol University, Bangkok (Thailand); Department of Physiology, Faculty of Science, Mahidol University, Bangkok (Thailand); Charoenphandhu, Narattaphol, E-mail: [Center of Calcium and Bone Research (COCAB), Faculty of Science, Mahidol University, Bangkok (Thailand); Department of Physiology, Faculty of Science, Mahidol University, Bangkok (Thailand)


    Highlights: Black-Right-Pointing-Pointer Mouse chondrogenic ATDC5 cells expressed PRL receptor mRNAs and proteins. Black-Right-Pointing-Pointer Low PRL concentration (10 ng/mL) increased chondrocyte viability and differentiation. Black-Right-Pointing-Pointer Higher PRL concentrations ( Greater-Than-Or-Slanted-Equal-To 100 ng/mL) decreased viability and increased apoptosis. -- Abstract: A recent investigation in lactating rats has provided evidence that the lactogenic hormone prolactin (PRL) increases endochondral bone growth and bone elongation, presumably by accelerating apoptosis of hypertrophic chondrocytes in the growth plate and/or subsequent chondrogenic matrix mineralization. Herein, we demonstrated the direct chondroregulatory action of PRL on proliferation, differentiation and apoptosis of chondrocytes in 3-dimensional micromass culture of mouse chondrogenic ATDC5 cell line. The results showed that ATDC5 cells expressed PRL receptor (PRLR) transcripts, and responded typically to PRL by downregulating PRLR expression. Exposure to a low PRL concentration of 10 ng/mL, comparable to the normal levels in male and non-pregnant female rats, increased chondrocyte viability, differentiation, proteoglycan accumulation, and mRNA expression of several chondrogenic differentiation markers, such as Sox9, ALP and Hspg2. In contrast, high PRL concentrations of Greater-Than-Or-Slanted-Equal-To 100 ng/mL, comparable to the levels in pregnancy or lactation, decreased chondrocyte viability by inducing apoptosis, with no effect on chondrogenic marker expression. It could be concluded that chondrocytes directly but differentially responded to non-pregnant and pregnant/lactating levels of PRL, thus suggesting the stimulatory effect of PRL on chondrogenesis in young growing individuals, and supporting the hypothesis of hypertrophic chondrocyte apoptosis in the growth plate of lactating rats.

  9. Endodontic Treatment of an Anomalous Anterior Tooth with the Aid of a 3-dimensional Printed Physical Tooth Model.

    Byun, Chanhee; Kim, Changhwan; Cho, Seungryong; Baek, Seung Hoon; Kim, Gyutae; Kim, Sahng G; Kim, Sun-Young


    Endodontic treatment of tooth formation anomalies is a challenge to clinicians and as such requires a complete understanding of the aberrant root canal anatomy followed by careful root canal disinfection and obturation. Here, we report the use of a 3-dimensional (3D) printed physical tooth model including internal root canal structures for the endodontic treatment of a challenging tooth anomaly. A 12-year-old boy was referred for endodontic treatment of tooth #8. The tooth showed class II mobility with swelling and a sinus tract in the buccal mucosa and periapical radiolucency. The tooth presented a very narrow structure between the crown and root by distal concavity and a severely dilacerated root. Moreover, a perforation site with bleeding and another ditching site were identified around the cervical area in the access cavity. A translucent physical tooth model carrying the information on internal root canal structures was built through a 3-step process: data acquisition by cone-beam computed tomographic scanning, virtual modeling by image processing, and manufacturing by 3D printing. A custom-made guide jig was then fabricated to achieve a safe and precise working path to the root canal. Endodontic procedures including access cavity preparation were performed using the physical tooth model and the guide jig. At the 7-month follow-up, the endodontically treated tooth showed complete periapical healing with no clinical signs and symptoms. This case report describes a novel method of endodontic treatment of an anomalous maxillary central incisor with the aid of a physical tooth model and a custom-made guide jig via 3D printing technique.

  10. Cost-Effectiveness Analysis of Intensity Modulated Radiation Therapy Versus 3-Dimensional Conformal Radiation Therapy for Anal Cancer

    Hodges, Joseph C., E-mail: [Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas (United States); Beg, Muhammad S. [Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, Texas (United States); Das, Prajnan [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Meyer, Jeffrey [Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas (United States)


    Purpose: To compare the cost-effectiveness of intensity modulated radiation therapy (IMRT) and 3-dimensional conformal radiation therapy (3D-CRT) for anal cancer and determine disease, patient, and treatment parameters that influence the result. Methods and Materials: A Markov decision model was designed with the various disease states for the base case of a 65-year-old patient with anal cancer treated with either IMRT or 3D-CRT and concurrent chemotherapy. Health states accounting for rates of local failure, colostomy failure, treatment breaks, patient prognosis, acute and late toxicities, and the utility of toxicities were informed by existing literature and analyzed with deterministic and probabilistic sensitivity analysis. Results: In the base case, mean costs and quality-adjusted life expectancy in years (QALY) for IMRT and 3D-CRT were $32,291 (4.81) and $28,444 (4.78), respectively, resulting in an incremental cost-effectiveness ratio of $128,233/QALY for IMRT compared with 3D-CRT. Probabilistic sensitivity analysis found that IMRT was cost-effective in 22%, 47%, and 65% of iterations at willingness-to-pay thresholds of $50,000, $100,000, and $150,000 per QALY, respectively. Conclusions: In our base model, IMRT was a cost-ineffective strategy despite the reduced acute treatment toxicities and their associated costs of management. The model outcome was sensitive to variations in local and colostomy failure rates, as well as patient-reported utilities relating to acute toxicities.

  11. Joint environmental assessment for western NPR-1 3-dimensional seismic project at Naval Petroleum Reserve No. 1, Kern County, California



    The Department of Energy (DOE), in conjunction with the Bureau of Land Management (BLM), has prepared an Environmental Assessment (DOE/EA-1124) to identify and evaluate the potential environmental impacts of the proposed geophysical seismic survey on and adjacent to the Naval Petroleum Reserve No.1 (NPR-1), located approximately 35 miles west of Bakersfield, California. NPR-1 is jointly owned and operated by the federal government and Chevron U.S.A. Production Company. The federal government owns about 78 percent of NPR-1, while Chevron owns the remaining 22 percent. The government`s interest is under the jurisdiction of DOE, which has contracted with Bechtel Petroleum Operations, Inc. (BPOI) for the operation and management of the reserve. The 3-dimensional seismic survey would take place on NPR-1 lands and on public and private lands adjacent to NPR-1. This project would involve lands owned by BLM, California Department of Fish and Game (CDFG), California Energy Commission (CEC), The Nature Conservancy, the Center for Natural Lands Management, oil companies (Chevron, Texaco, and Mobil), and several private individuals. The proposed action is designed to provide seismic data for the analysis of the subsurface geology extant in western NPR-1 with the goal of better defining the commercial limits of a currently producing reservoir (Northwest Stevens) and three prospective hydrocarbon bearing zones: the {open_quotes}A Fan{close_quotes} in Section 7R, the 19R Structure in Section 19R, and the 13Z Structure in Section 13Z. Interpreting the data is expected to provide NPR-1 owners with more accurate locations of structural highs, faults, and pinchouts to maximize the recovery of the available hydrocarbon resources in western NPR-1. Completion of this project is expected to increase NPR-1 recoverable reserves, and reduce the risks and costs associated with further exploration and development in the area.

  12. Rectal planning risk volume correlation with acute and late toxicity in 3-dimensional conformal radiation therapy for prostate cancer.

    Dias, R S; Giordani, A J; Souhami, L; Segreto, R A; Segreto, H R C


    The purpose of this study was to evaluate rectum motion during 3-Dimensional conformal radiation therapy (3D-CRT) in prostate cancer patients, to derive a planning volume at risk (PRV) and to correlate the PRV dose-volume histograms (DVH) with treatment complications.This study was conducted in two phases. Initially, the PRV was defined prospectively in 50 consecutive prostate cancer patients (Group 1) who received a radical course of 3-D CRT. Then, the obtained PRV was used in the radiotherapy planning of these same 50 patients plus another 59 prostate cancer patients (Group 2) previously treated between 2004 and 2008. All these patients' data, including the rectum and PRV DVHs, were correlated to acute and late complications, according to the Common Toxicity Criteria (CTC) v4.0.The largest displacement occurred in the anterior axis. Long-term gastrointestinal (GI) complications grade ≥ 2 were seen in 9.2% of the cases. Factors that influenced acute GI reactions were: doses at 25% (p 5 0.011) and 40% (p 5 0.005) of the rectum volume and at 40% of the PRV (p 5 0.012). The dose at 25% of the rectum volume (p 5 0.033) and acute complications ≥ grade 2 (p 5 0.018) were prognostic factors for long-term complications. The PRV DVH did not correlate with late toxicity. The rectum showed a significant inter-fraction motion during 3D-CRT for prostate cancer. PRV dose correlated with acute gastrointestinal complications and may be a useful tool to predict and reduce their occurrence.

  13. Optical coherence tomography (OCT) as a 3-dimensional imaging technique for non-destructive testing of roll-to-roll coated polymer solar cells

    Thrane, Lars; Jørgensen, Thomas Martini; Jørgensen, Mikkel


    We have recently demonstrated the first application of optical coherence tomography (OCT) as a 3-dimensional (3D) imaging technique to visualize the internal structure of complete multilayered polymer solar cell modules (Thrane et al., Solar Energy Materials & Solar Cells 97, 181-185 (2012)). The...

  14. Nanostructural evolution of Cr-rich precipitates in a Cu-Cr-Zr alloy during heat treatment studied by 3 dimensional atom probe

    Hatakeyama, Masahiko; Toyama, Takeshi; Nagai, Yasuyoshi;


    Nanostructural evolution of Cr (Cr-rich) precipitates in a Cu-0.78%Cr-0.13%Zr alloy has been studied after aging and overaging (reaging) by laser assisted local electrode 3 dimensional atom probe (Laser-LEAP). This material is a candidate for the first wall and divertor components of future fusion...

  15. Application of a parallel 3-dimensional hydrogeochemistry HPF code to a proposed waste disposal site at the Oak Ridge National Laboratory

    Gwo, Jin-Ping [Oak Ridge National Lab., TN (United States); Yeh, Gour-Tsyh [Pennsylvania State Univ., University Park, PA (United States). Dept. of Civil and Environmental Engineering


    The objectives of this study are (1) to parallelize a 3-dimensional hydrogeochemistry code and (2) to apply the parallel code to a proposed waste disposal site at the Oak Ridge National Laboratory (ORNL). The 2-dimensional hydrogeochemistry code HYDROGEOCHEM, developed at the Pennsylvania State University for coupled subsurface solute transport and chemical equilibrium processes, was first modified to accommodate 3-dimensional problem domains. A bi-conjugate gradient stabilized linear matrix solver was then incorporated to solve the matrix equation. We chose to parallelize the 3-dimensional code on the Intel Paragons at ORNL by using an HPF (high performance FORTRAN) compiler developed at PGI. The data- and task-parallel algorithms available in the HPF compiler proved to be highly efficient for the geochemistry calculation. This calculation can be easily implemented in HPF formats and is perfectly parallel because the chemical speciation on one finite-element node is virtually independent of those on the others. The parallel code was applied to a subwatershed of the Melton Branch at ORNL. Chemical heterogeneity, in addition to physical heterogeneities of the geological formations, has been identified as one of the major factors that affect the fate and transport of contaminants at ORNL. This study demonstrated an application of the 3-dimensional hydrogeochemistry code on the Melton Branch site. A uranium tailing problem that involved in aqueous complexation and precipitation-dissolution was tested. Performance statistics was collected on the Intel Paragons at ORNL. Implications of these results on the further optimization of the code were discussed.

  16. The proton-proton scattering without Coulomb force renormalization

    Glöckle W.


    Full Text Available We demonstrate numerically that proton-proton (pp scattering observables can be determined directly by standard short range methods using a screened pp Coulomb force without renormalization. We numerically investigate solutions of the 3-dimensional Lippmann-Schwinger (LS equation for an exponentially screened Coulomb potential. For the limit of large screening radii we confirm analytically predicted properties for off-shell, half-shell and on-shell elements of the Coulomb t-matrix.

  17. MR evaluation of the articular cartilage of the femoral head during traction. Correlation with resected femoral head

    Nakanishi, K. [Osaka Seamens Insurance Hospital (Japan). Dept. of Radiology; Tanaka, H.; Narumi, Y.; Nakamura, H. [Osaka Univ. Medical School (Japan). Dept. of Radiology; Nishii, T.; Masuhara, K. [Osaka Univ. Medical School (Japan). Dept. of Orthopedic Surgery


    Objective: The purpose was to evaluate the articular cartilage of the hip joint with MR during traction and compare the findings with the resected specimen or arthroscopic findings. Material and Methods: Eight healthy volunteers, 5 patients with osteonecrosis, 5 with acetabular dysplasia, and 5 with advanced osteoarthrosis underwent MR imaging to evaluate the articular cartilage of the hip joint. Coronal fat-suppressed 3D spoiled gradient-echo (SPGR) images were obtained during traction. Identical imaging was performed of all the resected femoral heads of the osteonecrosis and advanced osteoarthrosis patients, and was correlated with the macroscopic pathological findings. Results: The traction was effective and the femoral articular cartilage was clearly identified in all 8 control subjects, and in all cases of osteonecrosis and acetabular dysplasia. In 4 cases of osteonecrosis, chondral fracture was identified in the boundary between the necrosis and the normal area. In all cases of advanced osteoarthrosis, cartilage was identified only at the medial side. The MR images of osteonecrosis and advanced osteoarthrosis corresponded well with the MR images of the resected femoral heads and the macroscopic findings. (orig.)


    LI Qingwen; GUO Yi; WANG Huiqin; ZHENG Wanpeng; ZHENG Kunlun


    Purpose: To observe the therapeutic effect of acupuncture combined with traction and Qigong exercise for treatment of nerve-root type cervical spondylosis. Methods: A total of 130 nerve-root type cervical spondylosis patients were randomly divided into acupuncture + traction + Qigong-exercise (ATQE) group (n= 59), acupuncture +Qigong-exercise (AQE) group (n= 40) and traction + Qigong-exercise (TQE) group (n = 31 ). Main acupoints used were Fengchi (GB 20) and cervical Jiaji (EX-B 2) on the affected side. Results: After one month's treatment, in ATQE, AQE and TQE groups, 43 (72.88%), 18 (45.00%) and 12 (45. 16%) had remarkable amelioration, 14(23.72%), 14 (35.00%) and 10 (32.26%) were effective, and 2 (3.39%), 8 (20.00%) and 7 (22.58%) had no apparent changes with the total effective rates being 96.61%, 80.00 % and 77.41% respectively. The therapeutic effect of ATQE group was significantly superior to that of AQE and TQE groups (P< 0.01 ).

  19. Theoretical aspects and methods of parameters identification of the electric traction system devices. method of cyclic current-voltage characteristics



    Full Text Available Purpose. To define the characteristics of numerical calculations of mathematical model with one or more cyclic current voltage characteristics (CVC. This is an urgent problem, since any electric traction system device and electrified track in general, like non-linear passive or active two-terminal network in the present operating mode is described by current-voltage characteristic (CVC, which is based on the given input voltage and input current. Me-thodology. The electromagnetic process calculation in the power circuits of traction electric energy supply is the probabilistic task with solving nonlinear stochastic differential equations requiring for the development of special methods. Given the calculation difficulty, it is reasonable to perform them either by real CVC graph bypass or initially by applying its equivalent replacement with, for example, an ellipse. Findings. Numerical calculations of the mathematical model with one or more cyclic CVC can be performed by “real” CVC bypass or by "idealization" i. e. approximate replacement of real cyclic CVC. Originality. This paper presents the dynamic CVC of the DS3 and 2ES5K electric locomotives at different currents of electric locomotives. Practical value. Cyclic CVC normally and definitely can be applied in the system of electromagnetic state equations while transient state calculating in the traction system. Therefore while calculating the experimentally obtained CVC for the most “difficult and complex” (or/and the “easiest” mode is applied.

  20. In vivo MRI monitoring nerve regeneration of acute peripheral nerve traction injury following mesenchymal stem cell transplantation

    Duan, Xiao-Hui, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Cheng, Li-Na, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Zhang, Fang, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Liu, Jun, E-mail: [Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Guo, Ruo-Mi, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Zhong, Xiao-Mei, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Wen, Xue-Hua, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China); Shen, Jun, E-mail: [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)


    Objective: To assess the continuous process of nerve regeneration in acute peripheral nerve traction injury treated with mesenchymal stem cells (MSCs) transplantation using MRI. Materials and methods: 1 week after acute nerve traction injury was established in the sciatic nerve of 48 New Zealand white rabbits, 5 × 10{sup 5} MSCs and vehicle alone were grafted to the acutely distracted sciatic nerves each in 24 animals. Serial MRI and T1 and T2 measurements of the injured nerves were performed with a 1.5-T scanner and functional recovery was recorded over a 10-week follow-up period, with histological assessments performed at regular intervals. Results: Compared with vehicle control, nerves grafted with MSCs had better functional recovery and showed improved nerve regeneration, with a sustained increase of T1 and T2 values during the phase of regeneration. Conclusion: MRI could be used to monitor the enhanced nerve regeneration in acute peripheral nerve traction injury treated with MSC transplantation, reflected by a prolonged increase in T1 and T2 values of the injured nerves.

  1. The effectiveness of motorised lumbar traction in the management of LBP with lumbo sacral nerve root involvement: a feasibility study

    Gracey Jacqueline H


    Full Text Available Abstract Background Traction is commonly used for the treatment of low back pain (LBP, predominately with nerve root involvement; however its benefits remain to be established. The aim of this study was to test the feasibility of a pragmatic randomized controlled trial to compare the difference between two treatment protocols (manual therapy, exercise and advice, with or without traction in the management of acute/sub acute LBP with 'nerve root' involvement. Methods 30 LBP patients with nerve root pain were recruited and randomly assigned to one of two treatment groups. Primary outcome measures were the: McGill pain questionnaire, Roland Morris disability questionnaire, and the SF36 Questionnaire; recorded at baseline, discharge, 3 and 6 months post-discharge. Results 27 patients completed treatment with a loss of another four patients at follow up. Intention to treat analysis demonstrated an improvement in all outcomes at follow up points but there appeared to be little difference between the groups. Conclusion This study has shown that a trial recruiting patients with 'nerve root' problems is feasible. Further research based upon a fully powered trial is required to ascertain if the addition of traction has any benefit in the management of these patients. Trial Registration Registration number: ISRCTN78417198

  2. The role of optical coherence tomography in the diagnosis and treatment selection for proliferative diabetic retinopathy complicated by vitreomacular traction

    M. I. Kerimov


    Full Text Available Purpose: Identification of proliferative diabetic retinopathy complicated by vitreomacular traction syndrome and performance evaluation of 23 gauge (G pars plana vitrectomy using a spectral optical tomography (OCT.Material and methods: 18 eyes of 15 patients underwent 23 G pars plana vitrectomy for complications of proliferative diabetic retinopathy in 2009‑2012. Vitreomacular interface examination was performed by OCT with Spectral Cirrus HD (Carl Zeiss Meditec, Germany. Follow-up was 6 months to 3 years.Results: Mean visual acuity in operated eyes was 1,34±0,30 in LogMAR units, after surgery improved to 0,75±0,34. OCT showed normalization of macular anatomy with reduction of macular thickness.Conclusion: OCT remains a valuable tool as for anatomical localization of vitreomacular interface pathology, as well for surgical planning and changes after surgery in patients with proliferative diabetic retinopathy complicated by vitreomacular traction syndrome. 23 G vitrectomy allows to obtain satisfactory anatomical and functional results in different types of vitreomacular traction in patients with proliferative diabetic retinopathy.

  3. The role of optical coherence tomography in the diagnosis and treatment selection for proliferative diabetic retinopathy complicated by vitreomacular traction

    M. I. Kerimov


    Full Text Available Purpose: Identification of proliferative diabetic retinopathy complicated by vitreomacular traction syndrome and performance evaluation of 23 gauge (G pars plana vitrectomy using a spectral optical tomography (OCT.Material and methods: 18 eyes of 15 patients underwent 23 G pars plana vitrectomy for complications of proliferative diabetic retinopathy in 2009‑2012. Vitreomacular interface examination was performed by OCT with Spectral Cirrus HD (Carl Zeiss Meditec, Germany. Follow-up was 6 months to 3 years.Results: Mean visual acuity in operated eyes was 1,34±0,30 in LogMAR units, after surgery improved to 0,75±0,34. OCT showed normalization of macular anatomy with reduction of macular thickness.Conclusion: OCT remains a valuable tool as for anatomical localization of vitreomacular interface pathology, as well for surgical planning and changes after surgery in patients with proliferative diabetic retinopathy complicated by vitreomacular traction syndrome. 23 G vitrectomy allows to obtain satisfactory anatomical and functional results in different types of vitreomacular traction in patients with proliferative diabetic retinopathy.

  4. A generalized traction integral equation for Stokes flow, with applications to near-wall particle mobility and viscous erosion

    Mitchell, William H.; Spagnolie, Saverio E.


    A double-layer integral equation for the surface tractions on a body moving in a viscous fluid is derived which allows for the incorporation of a background flow and/or the presence of a plane wall. The Lorentz reciprocal theorem is used to link the surface tractions on the body to integrals involving the background velocity and stress fields on an imaginary bounding sphere (or hemisphere for wall-bounded flows). The derivation requires the velocity and stress fields associated with numerous fundamental singularity solutions which we provide for free-space and wall-bounded domains. Two sample applications of the method are discussed: we study the tractions on an ellipsoid moving near a plane wall, which provides a more detailed understanding of the well-studied glancing and reversing trajectories in the context of particle sedimentation, and the erosion of bodies by a viscous flow, in which the surface is ablated at a rate proportional to the local viscous shear stress. Simulations and analytical estimates suggest that a spherical body in a uniform flow first reduces nearly but not exactly to the drag minimizing profile and then vanishes in finite time. The shape dynamics of an eroding body in a shear flow and near a wall are also investigated. Stagnation points on the body surface lead generically to the formation of cusps, whose number depends on the flow configuration and/or the presence of nearby boundaries.

  5. Hydraulic system of traction bed for maintenance%牵引床液压系统的故障维修



    Neck lumbar traction bed is through the computer control motor and hydraulic transmission device, implementation of traditional Chinese medicine traction, Angle rotation and manual reduction action of a device, etc. Saving time and effort can well meet the needs of the treatment on lumbar disease. Based on the failure phenomenon of traction bed hydraulic transmission device, the composition and working principle analysis of the hydraulic system, concluded that failure of the hydraulic transmission device is due to the pressure gauge damaged or blocked between the tubing and the overflow valve, which allows users to quickly troubleshoot.%颈腰椎牵引床是通过计算机控制电机和液压传动装置,实现中医牵引、角度转动及手法复位等动作的治疗设备。该设备省时省力,能较好地满足治疗腰椎疾病的需要。根据牵引床液压传动装置出现的故障现象,分析液压系统的组成及其工作原理,判断造成液压传动装置的故障是由于压力表损坏或出油管与溢流阀之间的堵塞而引起,从而快捷地排除故障。

  6. Multiple incipient sensor faults diagnosis with application to high-speed railway traction devices.

    Wu, Yunkai; Jiang, Bin; Lu, Ningyun; Yang, Hao; Zhou, Yang


    This paper deals with the problem of incipient fault diagnosis for a class of Lipschitz nonlinear systems with sensor biases and explores further results of total measurable fault information residual (ToMFIR). Firstly, state and output transformations are introduced to transform the original system into two subsystems. The first subsystem is subject to system disturbances and free from sensor faults, while the second subsystem contains sensor faults but without any system disturbances. Sensor faults in the second subsystem are then formed as actuator faults by using a pseudo-actuator based approach. Since the effects of system disturbances on the residual are completely decoupled, multiple incipient sensor faults can be detected by constructing ToMFIR, and the fault detectability condition is then derived for discriminating the detectable incipient sensor faults. Further, a sliding-mode observers (SMOs) based fault isolation scheme is designed to guarantee accurate isolation of multiple sensor faults. Finally, simulation results conducted on a CRH2 high-speed railway traction device are given to demonstrate the effectiveness of the proposed approach.

  7. Microincision Vitrectomy Surgery in Vitreomacular Traction Syndrome of Retinitis Pigmentosa Patients

    Enzo Maria Vingolo


    Full Text Available Purpose. To investigate long-term retinal changes after microincision pars plana vitrectomy surgery (MIVS and internal limiting membrane (ILM peeling outcome in retinitis pigmentosa (RP patients affected by vitreomacular traction syndrome (VMT with higher vitreous surface adhesion or coexisting epiretinal membrane (ERM. Methods. Eight RP patients suffering from VMT were evaluated by means of best corrected visual acuity (BCVA, anterior and posterior binocular examination, spectral-domain optical coherence tomography (SD-OCT, MP-1 microperimetry (MP-1, and full-field electroretinogram (ERG, before MIVS and ILM peeling and during the 36-month follow-up. Patients were hospitalized for two days after the surgery. Surgical procedure was performed following this schedule: surgical removal of crystalline lens (MICS, MIVS with 23-gauge sutureless system trocars, core vitreous body removal, and balanced-sterile-salin-solution- (BSS- air-gas (SF6 exchange. Results. All patients presented visual acuity (VA increase after MIVS. None of the patients developed ocular hypertension or vitreomacular adhesions during the 3-year follow-up. MP-1 bivariate contour ellipse area (BCEA was reduced in its dimensions and improved in all patients demonstrating a better fixation. Conclusions. MIVS could be the gold standard therapy in RP patients with VMT and higher vitreous surface adhesion or coexisting ERM if medical therapy is not applicable or not effective.

  8. Treatment effects of Fränkel, activator and extraoral traction appliances.

    Righellis, E G


    The effects of the Fränkel appliance on the treatment of Class II, Division 1 malocclusion were compared with the activator, high-pull headgear, cervical traction and a control group. A sample of 16 Fränkel cases treated in the mixed dentition was tested in four craniofacial areas, with findings as follows: a. Maxillae, no significant horizontal effect b. Mandibular length, significantly increased c. Lower face height, widely variable effects. d. Less upper molar eruption and more lower molar eruption. Although the findings of this study should be interpreted as tentative, they do show the Fränkel appliance to have some different mean effects on the craniofacial complex. Variability is a most important aspect of the findings of this study. Future studies must deal not only with mean changes, but with the Fränkel appliance's variable effects on differential individuals. Optimal application of this appliance requires judgment in case selection and careful analysis of progress, using adequate follow-up records and a firm knowledge of normal growth and development of the craniofacial complex.

  9. Effect of moisture on the traction-separation behavior of cellulose nanocrystal interfaces

    Sinko, Robert [Department of Mechanical Engineering, Northwestern University, 2145 Sheridan Road, Room B224 Evanston, Illinois 60208 (United States); Keten, Sinan, E-mail: [Department of Mechanical Engineering, Northwestern University, 2145 Sheridan Road, Room B224 Evanston, Illinois 60208 (United States); Department of Civil and Environmental Engineering, Northwestern University, 2145 Sheridan Road, Room A136, Evanston, Illinois 60208 (United States)


    Interfaces and stress transfer between cellulose nanocrystals (CNCs) dictate the mechanical properties of hierarchical cellulose materials such as neat films and nanocomposites. An interesting question that remains is how the behavior of these interfaces changes due to environmental stimuli, most notably moisture. We present analyses on the traction-separation behavior between Iβ CNC elementary fibrils, providing insight into how the presence of a single atomic layer of water at these interfaces can drastically change the mechanical behavior. We find that molecular water at the interface between hydrophilic CNC surfaces has a negligible effect on the tensile separation adhesion energy. However, when water cannot hydrogen bond easily to the surface (i.e., hydrophobic surface), it tends to maintain hydrogen bonds with other water molecules across the interface and form a capillary bridge that serves to increase the energy required to separate the crystals. Under shear loading, water lowers the energy barriers to sliding by reducing the atomic friction and consequently the interlayer shear modulus between crystals. Our simulations indicate that these nanoscale interfaces and physical phenomena such as interfacial adhesion, interlayer shear properties, and stick-slip friction behavior can be drastically altered by the presence of water.

  10. Aspects of implementing constant traction boundary conditions in computational homogenization via semi-Dirichlet boundary conditions

    Javili, A.; Saeb, S.; Steinmann, P.


    In the past decades computational homogenization has proven to be a powerful strategy to compute the overall response of continua. Central to computational homogenization is the Hill-Mandel condition. The Hill-Mandel condition is fulfilled via imposing displacement boundary conditions (DBC), periodic boundary conditions (PBC) or traction boundary conditions (TBC) collectively referred to as canonical boundary conditions. While DBC and PBC are widely implemented, TBC remains poorly understood, with a few exceptions. The main issue with TBC is the singularity of the stiffness matrix due to rigid body motions. The objective of this manuscript is to propose a generic strategy to implement TBC in the context of computational homogenization at finite strains. To eliminate rigid body motions, we introduce the concept of semi-Dirichlet boundary conditions. Semi-Dirichlet boundary conditions are non-homogeneous Dirichlet-type constraints that simultaneously satisfy the Neumann-type conditions. A key feature of the proposed methodology is its applicability for both strain-driven as well as stress-driven homogenization. The performance of the proposed scheme is demonstrated via a series of numerical examples.

  11. Function of Train Traction Department and Railway Vehicles in Logistic Centres

    Velimir Kolar


    Full Text Available The increasing globalization has spread the production locationsto every part of the world thus increasing even more therole of transport in determining the price and quality of a product.Therefore, the producers and carriers join together moreand more frequently through the supply chains. Railway carriershave a very significant role in supply chains, both throughorganization of transport and forming the trains as final products,and through forming the logistic centres. Logistic centresare the starting and the final railway stations but also the meetingpoints of the national carrier with other carriers (sea, road,river as well as other railway carriers and they also represent informationcentres. For the quality of service at logistic centres, itis important to have well organized operation of train traction.In order to keep up the regulmity of trains and the quality oftransport at logistic centres, among other things, it is necessaryto provide an optimal number of locomotives and to providethe technical inspection place. Special attention should be paidto the organization of work peiformed by the engine staff At logisticcentres it is possible to organize high-quality technical inspectionof wagons thus increasing the traffic safety.

  12. Simulation of Induction Traction Drive with Supercapacitor Energy Storage System Test Bench

    Stana Girts


    Full Text Available The paper describes the application of supercapacitor energy storage system for induction traction drive test bench that replaces a real electric public transport for performing testing and researches. The suitability and usage of such bench for research purposes is explained and the importance of the development of software mathematical model for performing simulations to be done before physical implementation measures is reasoned. The working principle of the bench and applied components are described. A virtual model of the bench was built and simulations were performed using Matlab/Simulink software. The basic topology of the virtual bench model is described as well. The calculations of this work show the scaling of supercapacitor energy storage system by setting different limits of working voltage range in order to adjust them to test bench parameters, whereas the modelling compares two simulation cases – the application of less supercapacitors and the application of more supercapacitors with the same common rated voltage. The autonomous mode simulations were also performed. Simulation results are analyzed and recommendations for the application of the supercapacitor energy storage system, with respect to initial supercapacitor circuit voltage, are given.

  13. Redesigning services for the management of vitreomacular traction and macular hole.

    Amoaku, W; Cackett, P; Tyagi, A; Mahmood, U; Nosek, J; Mennie, G; Rumney, N


    Vitreomacular traction (VMT) and VMT with macular hole (MH) are serious conditions, being associated with visual disturbance, for example, metamorphopsia, and diminished visual acuity (VA). Pars plana vitrectomy is the routine treatment for symptomatic VMT and VMT+MH. However, ocriplasmin has demonstrated favourable efficacy and safety in specific patient groups with VMT/MH and is now recommended as a treatment option for certain patients by the National Institute of Health and Care Excellence. This means that services for managing patients with VMT/MH may need to be revised, as patients can now potentially receive treatment earlier in the course of the disease. VMT triage clinics could provide a more efficient way of managing VMT/MH patients. Patient assessment should always include high-definition optical coherence tomography, as this is the most accurate means of assessing abnormalities in the vitreoretinal (VR) interface, and an accurate measurement of best-corrected VA. It has been proposed that patients with VMT+MH be managed as a routine 6-week referral, with the complete patient journey-from initial referral to treatment-taking no longer than 6 months. It is important that patients are entered onto VR surgical lists so that there is no delay if ocriplasmin treatment is unsuccessful. Patients will need appropriate counselling about the expected outcomes and possible side effects of ocriplasmin treatment. One-year follow-up data should be collected by treatment centres in order to evaluate the new VMT service.

  14. Speed Ratio Prediction and Performance Analysis of Single Ball Traction Drive for CVT

    Kunal S. Marathe


    Full Text Available Drives are basically used to transmit power and speed from the prime mover to the machine. The power transmission and speed reduction between the prime-mover and the driven machine can be achieved by using conventional drives like Belt drive, Rope drive, Chain drive, Gears, etc. with their numerous advantages and disadvantages. There are many machines and mechanical units that under varying circumstances make it desirable to be able to drive at a barely perceptible speed, an intermediate speed or a high speed. Thus an infinitely variable (step less speed variation in which it is possible to get any desirable speed. Some mechanical, hydraulic, drives serve as such step less drives. However the torque versus speed characteristics of these drives do not match torque at low speeds. Hence the need of a step less or infinitely variable speed drive came into existence. The drive presented by the end of this research work is single ball traction drive for continuously variable transmission systems. Dissertation includes the brief history of existing drives, speed prediction methodology and performance analysis of the drive developed.

  15. Usefulness of MR arthrography of the hip with leg traction in the evaluation of ligamentum teres injuries

    Cerezal, Luis; Fernandez-Hernando, Moises [Department of Radiology, Diagnostico Medico Cantabria, Santander, Cantabria (Spain); Perez Carro, Luis [Learnig Trauma Med. Centro de Consultas Medicas CCM, Orthopedic Surgery department, Santander (Spain); Llorca, Javier [University of Cantabria - IDIVAL, Santander (Spain); CIBER Epidemiology and Public Health, Santander (Spain); Llopis, Eva [Alzira Hospital, Department of Radiology, Valencia (Spain); Montero, Juan Antonio [Cantabria University, Anatomy and Cell Biology, Santander (Spain); Canga, Ana [Cantabria University, Anatomy and Cell Biology, Santander (Spain); Department of Radiology Marques de Valdecilla University Hospital, Santander, Cantabria (Spain)


    To retrospectively evaluate the diagnostic accuracy of magnetic resonance (MR) arthrography of the hip with leg traction in the evaluation of ligamentum teres lesions and to evaluate whether there is increased articular distraction, possibly indicating secondary instability, in hips with ligamentum teres injuries. Institutional review board approval and informed consent were obtained for this retrospective study. MR arthrograms of the hip with leg traction of 184 consecutive patients, including 108 men (mean age, 32.6 years; range, 19-53 years) and 76 women (mean age, 38.5 years; range, 18-56 years), who underwent hip arthroscopy were assessed for the presence of ligamentum teres lesions. The MR arthrographic findings were independently assessed by two radiologists who were blinded to the arthroscopic results. The inclusion criteria stipulated no previous surgery, arthroscopy within 1 month after MR arthrography, and availability of a detailed surgical report with ligamentum teres findings. The arthroscopy findings served as the reference standard. Sensitivity, specificity, accuracy, and K statistics for interobserver and intraobserver agreement were calculated. At arthroscopy, 32 ligamentum teres injuries were found. The ligamentum teres was normal in 152 (82.6 %) patients and had suffered low-grade partial tears in 15 (8.1 %) patients, high-grade partial tears in 10 (5.4 %) patients, and complete ruptures in 7 (3.8 %) patients. MR arthrography with axial traction demonstrated moderate sensitivity and high specificity for both low-grade (62/93 %) and high-grade (66/96 %) partial tears. Grouping low- and high-grade partial tears increased the diagnostic performance of MR arthrography, yielding a sensitivity of 87 % and a specificity of 95 %. For complete ligamentum teres tears, MR arthrography with leg traction demonstrated high sensitivity (92 %) and specificity (98 %). Articular distraction was significantly increased in patients with complete ruptures of the

  16. Hydrogel Based 3-Dimensional (3D System for Toxicity and High-Throughput (HTP Analysis for Cultured Murine Ovarian Follicles.

    Hong Zhou

    Full Text Available Various toxicants, drugs and their metabolites carry potential ovarian toxicity. Ovarian follicles, the functional unit of the ovary, are susceptible to this type of damage at all stages of their development. However, despite of the large scale of potential negative impacts, assays that study ovarian toxicity are limited. Exposure of cultured ovarian follicles to toxicants of interest served as an important tool for evaluation of toxic effects for decades. Mouse follicles cultured on the bottom of a culture dish continue to serve an important approach for mechanistic studies. In this paper, we demonstrated the usefulness of a hydrogel based 3-dimensional (3D mouse ovarian follicle culture as a tool to study ovarian toxicity in a different setup. The 3D in vitro culture, based on fibrin alginate interpenetrating network (FA-IPN, preserves the architecture of the ovarian follicle and physiological structure-function relationship. We applied the novel 3D high-throughput (HTP in vitro ovarian follicle culture system to study the ovotoxic effects of an anti-cancer drug, Doxorobucin (DXR. The fibrin component in the system is degraded by plasmin and appears as a clear circle around the encapsulated follicle. The degradation area of the follicle is strongly correlated with follicle survival and growth. To analyze fibrin degradation in a high throughput manner, we created a custom MATLAB® code that converts brightfield micrographs of follicles encapsulated in FA-IPN to binary images, followed by image analysis. We did not observe any significant difference between manually processed images to the automated MATLAB® method, thereby confirming that the automated program is suitable to measure fibrin degradation to evaluate follicle health. The cultured follicles were treated with DXR at concentrations ranging from 0.005 nM to 200 nM, corresponding to the therapeutic plasma levels of DXR in patients. Follicles treated with DXR demonstrated decreased

  17. In-Core-Instrumentation Methods for 3-Dimensional Distribution Information of Reactor Core Temperatures and Melt-down

    Shin, Yeong Cheol [KHNP, Daejeon (Korea, Republic of); Eun, Myoung; Kim, Sung Jun [Woojin Inc., Hwaseong (Korea, Republic of)


    The tsunami-induced nuclear accident at Japanese Fukushima power plants in March 2011 has revealed some weaknesses in the severe accident monitoring system. The plant instrumentation did not provide utility, safety experts, and government officials with adequate and reliable information. The information on the reactor core damage and coolability is critical for making decisions correctly as well as in a timely manner during the course of the mitigation of severe accidents. Current Pressurized Water Reactor (PWR)s have an In-Core-Instrumentation (ICI) system that measures the temperature distribution of the top surface (i.e. Core Exit Temperatures) of the reactor core mainly to indicate when to begin Severe Accident Mitigation Guidelines (SAMG). This design concept giving only the core exit temperature has limitations in terms of sufficiency as well as availability of the information necessary for diagnosis on the status of the degraded core and the effectiveness of the measures taken as mitigation strategies. The reactor core exit temperatures are not sufficient to support the assessment of the degree of the core damage and the location of the molten core debris and recognition whether the core damage progresses on or it is mitigated. The ICI location being at the top of the reactor core also makes the ICI thermocouples vulnerable to melt-down because the upper part of the reactor core uncovers first, thereby melt down at the early stage of the accident. This means that direct indication of reactor core temperature will be lost and unavailable during the later stages of severe accident. To address the aforementioned weaknesses of the current ICIs, it is necessary to develop a new ICI system that provides information that is more expanded and more reliable for accident mitigation. With the enhanced information available, the SAMG can be prepared in more refined and effective way based on the direct and suitable indication of status of damages and the 3-dimensional

  18. On the Need for Comprehensive Validation of Deformable Image Registration, Investigated With a Novel 3-Dimensional Deformable Dosimeter

    Juang, Titania [Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina (United States); Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina (United States); Das, Shiva [Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina (United States); Adamovics, John; Benning, Ron [Department of Chemistry and Biology, Rider University, Lawrenceville, New Jersey (United States); Oldham, Mark, E-mail: [Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina (United States)


    Purpose: To introduce and evaluate a novel deformable 3-dimensional (3D) dosimetry system (Presage-Def/Optical-CT) and its application toward investigating the accuracy of dose deformation in a commercial deformable image registration (DIR) package. Methods and Materials: Presage-Def is a new dosimetry material consisting of an elastic polyurethane matrix doped with radiochromic leuco dye. Radiologic and mechanical properties were characterized using standard techniques. Dose-tracking feasibility was evaluated by comparing dose distributions between dosimeters irradiated with and without 27% lateral compression. A checkerboard plan of 5-mm square fields enabled precise measurement of true deformation using 3D dosimetry. Predicted deformation was determined from a commercial DIR algorithm. Results: Presage-Def exhibited a linear dose response with sensitivity of 0.0032 ΔOD/(Gy∙cm). Mass density is 1.02 g/cm{sup 3}, and effective atomic number is within 1.5% of water over a broad (0.03-10 MeV) energy range, indicating good water-equivalence. Elastic characteristics were close to that of liver tissue, with Young's modulus of 13.5-887 kPa over a stress range of 0.233-303 kPa, and Poisson's ratio of 0.475 (SE, 0.036). The Presage-Def/Optical-CT system successfully imaged the nondeformed and deformed dose distributions, with isotropic resolution of 1 mm. Comparison with the predicted deformed 3D dose distribution identified inaccuracies in the commercial DIR algorithm. Although external contours were accurately deformed (submillimeter accuracy), volumetric dose deformation was poor. Checkerboard field positioning and dimension errors of up to 9 and 14 mm, respectively, were identified, and the 3D DIR-deformed dose γ passing rate was only γ{sub 3%/3} {sub mm} = 60.0%. Conclusions: The Presage-Def/Optical-CT system shows strong potential for comprehensive investigation of DIR algorithm accuracy. Substantial errors in a commercial DIR were found in the

  19. A 3-Dimensional Model of Water-Bearing Sequences in the Dominguez Gap Region, Long Beach, California

    Ponti, Daniel J.; Ehman, Kenneth D.; Edwards, Brian D.; Tinsley, John C.; Hildenbrand, Thomas; Hillhouse, John W.; Hanson, Randall T.; McDougall, Kristen; Powell, Charles L.; Wan, Elmira; Land, Michael; Mahan, Shannon; Sarna-Wojcicki, Andrei M.


    A 3-dimensional computer model of the Quaternary sequence stratigraphy in the Dominguez gap region of Long Beach, California has been developed to provide a robust chronostratigraphic framework for hydrologic and tectonic studies. The model consists of 13 layers within a 16.5 by 16.1 km (10.25 by 10 mile) square area and extends downward to an altitude of -900 meters (-2952.76 feet). Ten sequences of late Pliocene to Holocene age are identified and correlated within the model. Primary data to build the model comes from five reference core holes, extensive high-resolution seismic data obtained in San Pedro Bay, and logs from several hundred water and oil wells drilled in the region. The model is best constrained in the vicinity of the Dominguez gap seawater intrusion barrier where a dense network of subsurface data exist. The resultant stratigraphic framework and geologic structure differs significantly from what has been proposed in earlier studies. An important new discovery from this approach is the recognition of ongoing tectonic deformation throughout nearly all of Quaternary time that has impacted the geometry and character of the sequences. Anticlinal folding along a NW-SE trend, probably associated with Quaternary reactivation of the Wilmington anticline, has uplifted and thinned deposits along the fold crest, which intersects the Dominguez gap seawater barrier near Pacific Coast Highway. A W-NW trending fault system that approximately parallels the fold crest has also been identified. This fault progressively displaces all but the youngest sequences down to the north and serves as the southern termination of the classic Silverado aquifer. Uplift and erosion of fining-upward paralic sequences along the crest of the young fold has removed or thinned many of the fine-grained beds that serve to protect the underlying Silverado aquifer from seawater contaminated shallow groundwater. As a result of this process, the potential exists for vertical migration of

  20. Forced Snaking

    Ponedel, Benjamin; Knobloch, Edgar


    We study spatial localization in the real subcritical Ginzburg-Landau equation ut =m0 u +m1 cos2/π l x u +uxx +d | u | 2 u -| u | 4 u with spatially periodic forcing. When d > 0 and m1 = 0 this equation exhibits bistability between the trivial state u = 0 and a homogeneous nontrivial state u =u0 with stationary localized structures which accumulate at the Maxwell point m0 = - 3d2 / 16 . When spatial forcing is included its wavelength is imprinted on u0 creating conditions favorable to front pinning and hence spatial localization. We use numerical continuation to show that under appropriate conditions such forcing generates a sequence of localized states organized within a snakes-and-ladders structure centered on the Maxwell point, and refer to this phenomenon as forced snaking. We determine the stability properties of these states and show that longer lengthscale forcing leads to stationary trains consisting of a finite number of strongly localized, weakly interacting pulses exhibiting foliated snaking.