WorldWideScience

Sample records for 3-d thermal evaluations

  1. Evaluation of Methods for Coregistration and Fusion of Rpas-Based 3d Point Clouds and Thermal Infrared Images

    Science.gov (United States)

    Hoegner, L.; Tuttas, S.; Xu, Y.; Eder, K.; Stilla, U.

    2016-06-01

    This paper discusses the automatic coregistration and fusion of 3d point clouds generated from aerial image sequences and corresponding thermal infrared (TIR) images. Both RGB and TIR images have been taken from a RPAS platform with a predefined flight path where every RGB image has a corresponding TIR image taken from the same position and with the same orientation with respect to the accuracy of the RPAS system and the inertial measurement unit. To remove remaining differences in the exterior orientation, different strategies for coregistering RGB and TIR images are discussed: (i) coregistration based on 2D line segments for every single TIR image and the corresponding RGB image. This method implies a mainly planar scene to avoid mismatches; (ii) coregistration of both the dense 3D point clouds from RGB images and from TIR images by coregistering 2D image projections of both point clouds; (iii) coregistration based on 2D line segments in every single TIR image and 3D line segments extracted from intersections of planes fitted in the segmented dense 3D point cloud; (iv) coregistration of both the dense 3D point clouds from RGB images and from TIR images using both ICP and an adapted version based on corresponding segmented planes; (v) coregistration of both image sets based on point features. The quality is measured by comparing the differences of the back projection of homologous points in both corrected RGB and TIR images.

  2. 3D Energy Harvester Evaluation

    Directory of Open Access Journals (Sweden)

    V. Janicek

    2013-04-01

    Full Text Available This paper discusses the characterization and evaluation of an MEMS based electrostatic generator, a part of the power supply unit of the self-powered microsystem[1,2,3]. The designed generator is based on electrostatic converter and uses the principle of conversion of non-electric energy into electrical energy by periodical modification of gap between electrodes of a capacitor [4]. The structure is designed and modeled as three-dimensional silicon based MEMS. Innovative approach involving the achievement of very low resonant frequency of the structure (about 100Hz by usage of modified long cantilever spring design, minimum area of the chip, 3D work mode, the ability to be tuned to reach desired parameters, proves promising directions of possible further development.

  3. Dynamics of 3D isolated thermal filaments

    CERN Document Server

    Walkden, N R; Militello, F; Omotani, J T

    2016-01-01

    Simulations have been carried out to establish how electron thermal physics, introduced in the form of a dynamic electron temperature, affects isolated filament motion and dynamics in 3D. It is found that thermal effects impact filament motion in two major ways when the filament has a significant temperature perturbation compared to its density perturbation: They lead to a strong increase in filament propagation in the bi-normal direction and a significant decrease in net radial propagation. Both effects arise from the temperature dependence of the sheath current which leads to a non-uniform floating potential, with the latter effect supplemented by faster pressure loss. The reduction in radial velocity can only occur when the filament cross-section loses angular symmetry. The behaviour is observed across different filament sizes and suggests that filaments with much larger temperature perturbations than density perturbations are more strongly confined to the near SOL region.

  4. 3D SURFACE GENERATION FROM AERIAL THERMAL IMAGERY

    Directory of Open Access Journals (Sweden)

    B. Khodaei

    2015-12-01

    Full Text Available Aerial thermal imagery has been recently applied to quantitative analysis of several scenes. For the mapping purpose based on aerial thermal imagery, high accuracy photogrammetric process is necessary. However, due to low geometric resolution and low contrast of thermal imaging sensors, there are some challenges in precise 3D measurement of objects. In this paper the potential of thermal video in 3D surface generation is evaluated. In the pre-processing step, thermal camera is geometrically calibrated using a calibration grid based on emissivity differences between the background and the targets. Then, Digital Surface Model (DSM generation from thermal video imagery is performed in four steps. Initially, frames are extracted from video, then tie points are generated by Scale-Invariant Feature Transform (SIFT algorithm. Bundle adjustment is then applied and the camera position and orientation parameters are determined. Finally, multi-resolution dense image matching algorithm is used to create 3D point cloud of the scene. Potential of the proposed method is evaluated based on thermal imaging cover an industrial area. The thermal camera has 640×480 Uncooled Focal Plane Array (UFPA sensor, equipped with a 25 mm lens which mounted in the Unmanned Aerial Vehicle (UAV. The obtained results show the comparable accuracy of 3D model generated based on thermal images with respect to DSM generated from visible images, however thermal based DSM is somehow smoother with lower level of texture. Comparing the generated DSM with the 9 measured GCPs in the area shows the Root Mean Square Error (RMSE value is smaller than 5 decimetres in both X and Y directions and 1.6 meters for the Z direction.

  5. 3D Energy Harvester Evaluation

    OpenAIRE

    V. Janicek; M. Husak

    2013-01-01

    This paper discusses the characterization and evaluation of an MEMS based electrostatic generator, a part of the power supply unit of the self-powered microsystem[1,2,3]. The designed generator is based on electrostatic converter and uses the principle of conversion of non-electric energy into electrical energy by periodical modification of gap between electrodes of a capacitor [4]. The structure is designed and modeled as three-dimensional silicon based MEMS. Innovative approach involving th...

  6. Multimodal Registration and Fusion for 3D Thermal Imaging

    Directory of Open Access Journals (Sweden)

    Moulay A. Akhloufi

    2015-01-01

    Full Text Available 3D vision is an area of computer vision that has attracted a lot of research interest and has been widely studied. In recent years we witness an increasing interest from the industrial community. This interest is driven by the recent advances in 3D technologies, which enable high precision measurements at an affordable cost. With 3D vision techniques we can conduct advanced manufactured parts inspections and metrology analysis. However, we are not able to detect subsurface defects. This kind of detection is achieved by other techniques, like infrared thermography. In this work, we present a new registration framework for 3D and thermal infrared multimodal fusion. The resulting fused data can be used for advanced 3D inspection in Nondestructive Testing and Evaluation (NDT&E applications. The fusion permits the simultaneous visible surface and subsurface inspections to be conducted in the same process. Experimental tests were conducted with different materials. The obtained results are promising and show how these new techniques can be used efficiently in a combined NDT&E-Metrology analysis of manufactured parts, in areas such as aerospace and automotive.

  7. Thermal Protection System Materials (TPSM): 3D MAT Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The 3D MAT Project seeks to design and develop a game changing Woven Thermal Protection System (TPS) technology tailored to meet the needs of the Orion...

  8. Evaluation of the thermal and hydraulic performances of a very thin sintered copper flat heat pipe for 3D microsystem packages

    CERN Document Server

    Tzanova, S; Avenas, Y; Schaeffer, Ch

    2008-01-01

    The reported research work presents numerical studies validated by experimental results of a flat micro heat pipe with sintered copper wick structure. The objectives of this project are to produce and demonstrate the efficiency of the passive cooling technology (heat pipe) integrated in a very thin electronic substrate that is a part of a multifunctional 3-D electronic package. The enhanced technology is dedicated to the thermal management of high dissipative microsystems having heat densities of more than 10W/cm2. Future applications are envisaged in the avionics sector. In this research 2D numerical hydraulic model has been developed to investigate the performance of a very thin flat micro heat pipe with sintered copper wick structure, using water as a refrigerant. Finite difference method has been used to develop the model. The model has been used to determine the mass transfer and fluid flow in order to evaluate the limits of heat transport capacity as functions of the dimensions of the wick and the vapou...

  9. Reduction of thermal conductivity by nanoscale 3D phononic crystal.

    Science.gov (United States)

    Yang, Lina; Yang, Nuo; Li, Baowen

    2013-01-01

    We studied how the period length and the mass ratio affect the thermal conductivity of isotopic nanoscale three-dimensional (3D) phononic crystal of Si. Simulation results by equilibrium molecular dynamics show isotopic nanoscale 3D phononic crystals can significantly reduce the thermal conductivity of bulk Si at high temperature (1000 K), which leads to a larger ZT than unity. The thermal conductivity decreases as the period length and mass ratio increases. The phonon dispersion curves show an obvious decrease of group velocities in 3D phononic crystals. The phonon's localization and band gap is also clearly observed in spectra of normalized inverse participation ratio in nanoscale 3D phononic crystal.

  10. Simulation of Missing Pellet Surface thermal behavior with 3D dynamic gap element

    International Nuclear Information System (INIS)

    Most of the fuel performance codes that are able to simulate a multidimensional analysis are used to calculate the radial temperature distribution and perform a multidimensional mechanical analysis based on a one-dimensional (1D) temperature result. The FRAPCON-FRAPTRAN code system incorporates a 1D thermal module and two-dimensional (2D) mechanical module when FEM option is activated. In this method, the multidimensional gap conductance model is not required because one-dimensional thermal analysis is carried out. On the other hand, a gap conductance model for a multi-dimension should be developed in the code to perform a multidimensional thermal analysis. ALCYONE developed by CEA introduces an equivalent heat convection coefficient that represents the multidimensional gap conductance. However, the code does not employ dynamic gap conductance which is a function of gap thickness and gap characteristics in direct. The BISON code, which has been developed by INL (Idaho National Laboratory), employed a thermo-mechanical contact method that is specifically designed for tightly-coupled implicit solutions that employ Jacobian-free solution methods. Owing to tightly-coupled implicit solutions, the BISON code solves gap conductance and gap thickness simultaneously with given boundary conditions. In this paper, 3D dynamic gap element has been proposed to resolve convergence issue and nonlinear characteristic of multidimensional gap conductance. To evaluate 3D dynamic gap element module, 3D thermomechanical module using FORTRAN77 has been implemented incorporating 3D dynamic gap element. To demonstrate effect of 3D dynamic gap element, thermal behavior of missing pellet surface (MPS) has been simulated by the developed module. LWR fuel performance codes should incorporate thermo-mechanical loop to solve gap conductance problem, iteratively. However, gap conductance in multidimensional model is difficult issue owing to its nonlinearity and convergence characteristics. In

  11. Performance Evaluation of 3d Modeling Software for Uav Photogrammetry

    Science.gov (United States)

    Yanagi, H.; Chikatsu, H.

    2016-06-01

    UAV (Unmanned Aerial Vehicle) photogrammetry, which combines UAV and freely available internet-based 3D modeling software, is widely used as a low-cost and user-friendly photogrammetry technique in the fields such as remote sensing and geosciences. In UAV photogrammetry, only the platform used in conventional aerial photogrammetry is changed. Consequently, 3D modeling software contributes significantly to its expansion. However, the algorithms of the 3D modelling software are black box algorithms. As a result, only a few studies have been able to evaluate their accuracy using 3D coordinate check points. With this motive, Smart3DCapture and Pix4Dmapper were downloaded from the Internet and commercial software PhotoScan was also employed; investigations were performed in this paper using check points and images obtained from UAV.

  12. An Evaluative Review of Simulated Dynamic Smart 3d Objects

    Science.gov (United States)

    Romeijn, H.; Sheth, F.; Pettit, C. J.

    2012-07-01

    Three-dimensional (3D) modelling of plants can be an asset for creating agricultural based visualisation products. The continuum of 3D plants models ranges from static to dynamic objects, also known as smart 3D objects. There is an increasing requirement for smarter simulated 3D objects that are attributed mathematically and/or from biological inputs. A systematic approach to plant simulation offers significant advantages to applications in agricultural research, particularly in simulating plant behaviour and the influences of external environmental factors. This approach of 3D plant object visualisation is primarily evident from the visualisation of plants using photographed billboarded images, to more advanced procedural models that come closer to simulating realistic virtual plants. However, few programs model physical reactions of plants to external factors and even fewer are able to grow plants based on mathematical and/or biological parameters. In this paper, we undertake an evaluation of plant-based object simulation programs currently available, with a focus upon the components and techniques involved in producing these objects. Through an analytical review process we consider the strengths and weaknesses of several program packages, the features and use of these programs and the possible opportunities in deploying these for creating smart 3D plant-based objects to support agricultural research and natural resource management. In creating smart 3D objects the model needs to be informed by both plant physiology and phenology. Expert knowledge will frame the parameters and procedures that will attribute the object and allow the simulation of dynamic virtual plants. Ultimately, biologically smart 3D virtual plants that react to changes within an environment could be an effective medium to visually represent landscapes and communicate land management scenarios and practices to planners and decision-makers.

  13. Thermal and mechanical properties of selected 3D printed thermoplastics in the cryogenic temperature regime

    Science.gov (United States)

    Weiss, K.-P.; Bagrets, N.; Lange, C.; Goldacker, W.; Wohlgemuth, J.

    2015-12-01

    Insulating materials for use in cryogenic boundary conditions are still limited to a proved selection as Polyamid, Glasfiber reinforced resins, PEEK, Vespel etc. These materials are usually formed to parts by mechanical machining or sometimes by cast methods. Shaping complex geometries in one piece is limited. Innovative 3D printing is now an upcoming revolutionary technology to construct functional parts from a couple of thermoplastic materials as ABS, Nylon and others which possess quite good mechanical stability and allow realizing very complex shapes with very subtle details. Even a wide range of material mixtures is an option and thermal treatments can be used to finish the material structure for higher performance. The use of such materials in cryogenic environment is very attractive but so far poor experience exists. In this paper, first investigations of the thermal conductivity, expansion and mechanical strength are presented for a few selected commercial 3D material samples to evaluate their application prospects in the cryogenic temperature regime.

  14. 3D thermal modeling of TRISO fuel coupled with neutronic simulation

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jianwei [Los Alamos National Laboratory; Uddin, Rizwan [UNIV OF ILLINIOS

    2010-01-01

    The Very High Temperature Gas Reactor (VHTR) is widely considered as one of the top candidates identified in the Next Generation Nuclear Power-plant (NGNP) Technology Roadmap under the U.S . Depanment of Energy's Generation IV program. TRlSO particle is a common element among different VHTR designs and its performance is critical to the safety and reliability of the whole reactor. A TRISO particle experiences complex thermo-mechanical changes during reactor operation in high temperature and high burnup conditions. TRISO fuel performance analysis requires evaluation of these changes on micro scale. Since most of these changes are temperature dependent, 3D thermal modeling of TRISO fuel is a crucial step of the whole analysis package. In this paper, a 3D numerical thermal model was developed to calculate temperature distribution inside TRISO and pebble under different scenarios. 3D simulation is required because pebbles or TRISOs are always subjected to asymmetric thermal conditions since they are randomly packed together. The numerical model was developed using finite difference method and it was benchmarked against ID analytical results and also results reported from literature. Monte-Carlo models were set up to calculate radial power density profile. Complex convective boundary condition was applied on the pebble outer surface. Three reactors were simulated using this model to calculate temperature distribution under different power levels. Two asymmetric boundary conditions were applied to the pebble to test the 3D capabilities. A gas bubble was hypothesized inside the TRISO kernel and 3D simulation was also carried out under this scenario. Intuition-coherent results were obtained and reported in this paper.

  15. Plastinated fetus: 3D CT scan (VRT) evaluation

    OpenAIRE

    Shilpi Tiwari; Nandlal, B; N M Shama Sundar

    2012-01-01

    Objective: The intent of this study was to evaluate the effect of plastination on the morphology and structure of stored organs, to find out how much accuracy a plastinated specimen has, and to look into the changes that occurred because of plastination. Materials and Methods: A human fetus of gestational age 24 weeks was plastinated, and 3D CT scan evaluation of the fetus was done. Results: The results showed normal, well-defined, clearly identifiable organs, with no alteration in morp...

  16. Development and Evaluation of Gold 3D Cylindrical Nanoelectrode Ensembles

    Institute of Scientific and Technical Information of China (English)

    CAO Li-Xin; YAN Pei-Sheng; SUN Ke-Ning; KIRK W Donald

    2007-01-01

    Gold 3D cylindrical nanoelectrode ensembles (NEEs), 100 nm in diameter and 500 nm in length were prepared by electroless template synthesis in polycarbonate filter membranes, followed by selective controlled chemical etching. The morphology of the nanowires and cylindrical NEEs was imaged by scanning electron microscopy. The protruding nanoelectrodes were in good parallel order. EDX study showed that the nanoelectrode elements consisted of pure gold. The electrochemical evaluation of the 3D electrodes was conducted using the well known [Fe(CN)6]3-/[Fe(CN)6]4- couple. Cyclic voltammgrams (CV) show a very low double layer charging current and a higher ratio of signal to background current than 2D disc NEEs. Electrochemical impedance spectroscopy (EIS) indicates that the 3D cylindrical NEEs effectively accelerate the charge transfer process, which is in consistent with the results of CV. The linear relationship with a slope of 0.5 between lg Ipc and lg v shows that linear diffusion is dominant on the 3D cylindrical NEEs at conventional scan rates.

  17. Subjective evaluation of a 3D videoconferencing system

    Science.gov (United States)

    Rizek, Hadi; Brunnström, Kjell; Wang, Kun; Andrén, Börje; Johanson, Mathias

    2014-03-01

    A shortcoming of traditional videoconferencing systems is that they present the user with a flat, two-dimensional image of the remote participants. Recent advances in autostereoscopic display technology now make it possible to develop video conferencing systems supporting true binocular depth perception. In this paper, we present a subjective evaluation of a prototype multiview autostereoscopic video conferencing system and suggest a number of possible improvements based on the results. Whereas methods for subjective evaluation of traditional 2D videoconferencing systems are well established, the introduction of 3D requires an extension of the test procedures to assess the quality of depth perception. For this purpose, two depth-based test tasks have been designed and experiments have been conducted with test subjects comparing the 3D system to a conventional 2D video conferencing system. The outcome of the experiments show that the perception of depth is significantly improved in the 3D system, but the overall quality of experience is higher in the 2D system.

  18. Evaluating lubricant performance by 3D profilometry of wear scars

    Science.gov (United States)

    Georgescu, C.; Deleanu, L.; Pirvu, C.

    2016-08-01

    Due to improvement in analysing surface texture and optical instruments for investigating the texture surface, the authors propose to evaluate the lubricant performance by analysing the change in several 3D parameters in comparison to an analysis on 2D profile. All the surface of the wear scar generated on the four ball machine is investigated and the conclusion is that from the tribological point of view, the 3D parameters reflect better the surface quality evolution after testing. Investigation was done on the wear scars generated on the three fixed balls, for five lubricants: a non-additivated transmission mineral oil (T90), two grades of rapeseed oil (coarse degummed and refined) and two grades of soybean oil (coarse and degummed).

  19. 3D printing of new biobased unsaturated polyesters by microstereo-thermal-lithography

    International Nuclear Information System (INIS)

    New micro three-dimensional (3D) scaffolds using biobased unsaturated polyesters (UPs) were prepared by microstereo-thermal-lithography (μSTLG). This advanced processing technique offers indubitable advantages over traditional printing methods. The accuracy and roughness of the 3D structures were evaluated by scanning electron microscopy and infinite focus microscopy, revealing a suitable roughness for cell attachment. UPs were synthesized by bulk polycondensation between biobased aliphatic diacids (succinic, adipic and sebacic acid) and two different glycols (propylene glycol and diethylene glycol) using fumaric acid as the source of double bonds. The chemical structures of the new oligomers were confirmed by proton nuclear magnetic resonance spectra, attenuated total reflectance Fourier transform infrared spectroscopy and matrix assisted laser desorption/ionization-time of flight mass spectrometry. The thermal and mechanical properties of the UPs were evaluated to determine the influence of the diacid/glycol ratio and the type of diacid in the polyester’s properties. In addition an extensive thermal characterization of the polyesters is reported. The data presented in this work opens the possibility for the use of biobased polyesters in additive manufacturing technologies as a route to prepare biodegradable tailor made scaffolds that have potential applications in a tissue engineering area. (paper)

  20. 3D Printing Fabrication of Amorphous Thermoelectric Materials with Ultralow Thermal Conductivity.

    Science.gov (United States)

    He, Minhong; Zhao, Yan; Wang, Biao; Xi, Qing; Zhou, Jun; Liang, Ziqi

    2015-11-25

    Thermoelectric materials are prepared by developing 3D printing technology. The 3D fabricated Bi0.5 Sb1.5 Te3 samples exhibit amorphous characteristics and thus show an ultralow thermal conductivity of 0.2 W m(-1) K(-1) . 3D printing fabrication readily generates bulk thermoelectric samples of any shape, which is not the case with traditional hot-pressing and spark plasma sintering methods.

  1. Study of the thermal properties of filaments for 3D printing

    Science.gov (United States)

    Trhlíková, Lucie; Zmeskal, Oldrich; Psencik, Petr; Florian, Pavel

    2016-07-01

    Various materials are used for 3D printing, most commonly Acrylonitrile butadiene styrene (ABS), Polylactic acid (PLA), Polyethylene (PET) and Polypropylene (PP). These materials differ mainly in their melting point, which significantly influences the properties of the final products. Filaments are melted in the print head during the printing process. The temperature range is from 150 °C to 250 °C depending on the technology used. The optimum temperature for the cooling substrate on which printing is carried out is chosen so as to ensure uniform cooling and deformation. It generally varies between (40 - 100) °C. From the above it is clear that both temperatures can significantly affect the properties of the printed 3D object. It is therefore important to determine the thermal parameters (thermal conductivity, specific heat and thermal diffusivity) of the materials used across the entire range of temperatures. For evaluating the properties of different types of PLA materials, the step transient method was used, which allows determination of all required parameters using a fractal heat transfer model.

  2. 3D neutronic/thermal-hydraulic coupled analysis of MYRRHA

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez, M.; Martin-Fuertes, F. [CIEMAT, Avda. Complutense 40, 28040 Madrid (Spain)

    2012-07-01

    The current tendency in multiphysics calculations applied to reactor physics is the use of already validated computer codes, coupled by means of an iterative approach. In this paper such an approach is explained concerning neutronics and thermal-hydraulics coupled analysis with MCNPX and COBRA-IV codes using a driver program and file exchange between codes. MCNPX provides the neutronic analysis of heterogeneous nuclear systems, both in critical and subcritical states, while COBRA-IV is a subchannel code that can be used for rod bundles or core thermal-hydraulics analysis. In our model, the MCNP temperature dependence of nuclear data is handled via pseudo-material approach, mixing pre-generated cross section data set to obtain the material with the desired cross section temperature. On the other hand, COBRA-IV has been updated to allow for the simulation of liquid metal cooled reactors. The coupled computational tool can be applied to any geometry and coolant, as it is the case of single fuel assembly, at pin-by-pin level, or full core simulation with the average pin of each fuel-assembly. The coupling tool has been applied to the critical core layout of the SCK-CEN MYRRHA concept, an experimental LBE cooled fast reactor presently in engineering design stage. (authors)

  3. Development of a coupled 1D-3D thermal-hydraulic code for nuclear power plant simulation and its application to a pressurized thermal shock scenario in PWR

    International Nuclear Information System (INIS)

    Thermal-hydraulic (TH) system codes are developed for the evaluation and improvement of the design and safety of nuclear facilities. Since the numerical modeling of the thermal-hydraulic processes is 1D in nature, these programs have only limited capabilities to predict in detail 3D flows and coolant mixing processes. In contrast, computational fluid dynamics (CFD) software tools are used for 3D flow calculations with high spatial resolution. In order to realistically and efficiently simulate the thermal-hydraulic phenomena in a nuclear power plant (NPP), GRS has developed a methodology for the coupling of the TH system code ATHLET with the 3D CFD software ANSYS CFX. Within the European project NURISP validation activities for the 1D-3D code ATHLET - ANSYS CFX based on a Pressurized Thermal Shock (PTS) related experiment are performed. (author)

  4. Evaluation of vision training using 3D play game

    Science.gov (United States)

    Kim, Jung-Ho; Kwon, Soon-Chul; Son, Kwang-Chul; Lee, Seung-Hyun

    2015-03-01

    The present study aimed to examine the effect of the vision training, which is a benefit of watching 3D video images (3D video shooting game in this study), focusing on its accommodative facility and vergence facility. Both facilities, which are the scales used to measure human visual performance, are very important factors for man in leading comfortable and easy life. This study was conducted on 30 participants in their 20s through 30s (19 males and 11 females at 24.53 ± 2.94 years), who can watch 3D video images and play 3D game. Their accommodative and vergence facility were measured before and after they watched 2D and 3D game. It turned out that their accommodative facility improved after they played both 2D and 3D games and more improved right after they played 3D game than 2D game. Likewise, their vergence facility was proved to improve after they played both 2D and 3D games and more improved soon after they played 3D game than 2D game. In addition, it was demonstrated that their accommodative facility improved to greater extent than their vergence facility. While studies have been so far conducted on the adverse effects of 3D contents, from the perspective of human factor, on the imbalance of visual accommodation and convergence, the present study is expected to broaden the applicable scope of 3D contents by utilizing the visual benefit of 3D contents for vision training.

  5. Catheter-Based Ultrasound for 3D Control of Thermal Therapy

    Science.gov (United States)

    Diederich, Chris; Chen, Xin; Wootton, Jeffery; Juang, Titania; Nau, Will H.; Kinsey, Adam; Hsu, I.-Chow; Rieke, Viola; Pauly, Kim Butts; Sommer, Graham; Bouley, Donna

    2009-04-01

    Catheter-based ultrasound applicators have been investigated for delivering hyperthermia and thermal ablation for the treatment of cancer and benign diseases. Technology includes an intrauterine applicator integrated with an HDR ring applicator, interstitial applicators for hyperthermia delivery during brachytherapy, interstitial applicators for tumor ablation, and transurethral devices for conformal prostate ablation. Arrays of multiple sectored tubular transducers have been fabricated for interstitial and intrauterine hyperthermia applicators. High-power interstitial versions have been evaluated for percutaneous implantation with directional or dynamic angular control of thermal ablation. Transurethral applicators include curvilinear transducers with rotational sweeping of narrow heating patterns, and multi-sectored tubular devices capable of dynamic angular control without applicator movement. Performance was evaluated in phantom, excised tissue, in vivo experiments in canine prostate under MR temperature monitoring, clinical hyperthermia, and 3D-biothermal simulations with patient anatomy. Interstitial and intrauterine devices can tailor hyperthermia to large treatment volumes, with multisectored control useful to limit exposure to rectum and bladder. Curvilinear transurethral devices with sequential rotation produce target conforming coagulation zones that can cover either the whole gland or defined focal regions. Multi-sectored transurethral applicators can dynamically control the angular heating profile and target large regions of the prostate without applicator manipulation. High-power interstitial implants with directional devices can be used to effectively ablate defined target regions while avoiding sensitive tissues. MR temperature monitoring can effectively define the extent of thermal damage and provided a means for real-time control of the applicators. In summary, these catheter-based ultrasound devices allow for dynamic control of heating profiles

  6. 3D thermal medical image visualization tool: Integration between MRI and thermographic images.

    Science.gov (United States)

    Abreu de Souza, Mauren; Chagas Paz, André Augusto; Sanches, Ionildo Jóse; Nohama, Percy; Gamba, Humberto Remigio

    2014-01-01

    Three-dimensional medical image reconstruction using different images modalities require registration techniques that are, in general, based on the stacking of 2D MRI/CT images slices. In this way, the integration of two different imaging modalities: anatomical (MRI/CT) and physiological information (infrared image), to generate a 3D thermal model, is a new methodology still under development. This paper presents a 3D THERMO interface that provides flexibility for the 3D visualization: it incorporates the DICOM parameters; different color scale palettes at the final 3D model; 3D visualization at different planes of sections; and a filtering option that provides better image visualization. To summarize, the 3D thermographc medical image visualization provides a realistic and precise medical tool. The merging of two different imaging modalities allows better quality and more fidelity, especially for medical applications in which the temperature changes are clinically significant.

  7. General 3D Lumped Thermal Model with Various Boundary Conditions for High Power IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2016-01-01

    Accurate thermal dynamics modeling of high power Insulated Gate Bipolar Transistor (IGBT) modules is important information for the reliability analysis and thermal design of power electronic systems. However, the existing thermal models have their limits to correctly predict these complicated...... thermal behaviors in the IGBTs. In this paper, a new three-dimensional (3D) lumped thermal model is proposed, which can easily be characterized from Finite Element Methods (FEM) based simulation and acquire the thermal distribution in critical points. Meanwhile the boundary conditions including...... the cooling system and power losses are modeled in the 3D thermal model, which can be adapted to different real field applications of power electronic converters. The accuracy of the proposed thermal model is verified by experimental results....

  8. Optimisation of trench isolated bipolar transistors on SOI substrates by 3D electro-thermal simulations

    Science.gov (United States)

    Nigrin, S.; Armstrong, G. A.; Kranti, A.

    2007-09-01

    This paper provides a comprehensive analysis of thermal resistance of trench isolated bipolar transistors on SOI substrates based on 3D electro-thermal simulations calibrated to experimental data. The impact of emitter length, width, spacing and number of emitter fingers on thermal resistance is analysed in detail. The results are used to design and optimise transistors with minimum thermal resistance and minimum transistor area.

  9. PERFORMANCE EVALUATION OF 3D MODELING SOFTWARE FOR UAV PHOTOGRAMMETRY

    OpenAIRE

    Yanagi, H; H. Chikatsu

    2016-01-01

    UAV (Unmanned Aerial Vehicle) photogrammetry, which combines UAV and freely available internet-based 3D modeling software, is widely used as a low-cost and user-friendly photogrammetry technique in the fields such as remote sensing and geosciences. In UAV photogrammetry, only the platform used in conventional aerial photogrammetry is changed. Consequently, 3D modeling software contributes significantly to its expansion. However, the algorithms of the 3D modelling software are black box algori...

  10. Performance evaluation of 3D-TV systems

    NARCIS (Netherlands)

    kaptein, R.G.; Kuijsters, A.; Lambooij, M.T.M.; IJsselsteijn, W.A.; Heynderickx, I.

    2008-01-01

    The image quality circle is a commonly accepted framework to model the relation between the technology variables of a display and the resulting image quality. 3D-TV systems, however, go beyond the concept of image quality. Research has shown that, although 3D scenes are clearly more appreciated by s

  11. TORT-TD/ATTICA3D: a coupled neutron transport and thermal hydraulics code system for 3-D transient analysis of gas cooled high temperature reactors

    International Nuclear Information System (INIS)

    Comprehensive safety studies of high temperature gas cooled reactors (HTR) require full three dimensional coupled treatments of both neutron kinetics and thermal-hydraulics. In a common effort, GRS and IKE developed the coupled code system TORT-TD/ATTICA3D for pebble bed type HTR that connects the 3-D transient discrete-ordinates transport code TORT-TD with the 3-D porous medium thermal-hydraulics code ATTICA3D. In this paper, the physical models and calculation capabilities of TORT-TD and ATTICA3D are presented, focusing on model improvements in ATTICA3D and extensions made in TORT-TD related to HTR application. For first applications, the OECD/NEA/NSC PBMR-400 benchmark has been chosen. Results obtained with TORT-TD/ATTICA3D will be shown for transient exercises, e.g. control rod withdrawal and a control rod ejection. Results are compared to other benchmark participants' solutions with special focus on fuel temperature modelling features of ATTICA3D. The provided “grey-curtain” nuclear cross section libraries have been used. First results on 3-D effects during a control rod withdrawal transient will be presented. (author)

  12. Computation of thermal properties via 3D homogenization of multiphase materials using FFT-based accelerated scheme

    CERN Document Server

    Lemaitre, Sophie; Choi, Daniel; Karamian, Philippe

    2015-01-01

    In this paper we study the thermal effective behaviour for 3D multiphase composite material consisting of three isotropic phases which are the matrix, the inclusions and the coating media. For this purpose we use an accelerated FFT-based scheme initially proposed in Eyre and Milton (1999) to evaluate the thermal conductivity tensor. Matrix and spherical inclusions media are polymers with similar properties whereas the coating medium is metallic hence better conducting. Thus, the contrast between the coating and the others media is very large. For our study, we use RVEs (Representative volume elements) generated by RSA (Random Sequential Adsorption) method developed in our previous works, then, we compute effective thermal properties using an FFT-based homogenization technique validated by comparison with the direct finite elements method. We study the thermal behaviour of the 3D-multiphase composite material and we show what features should be taken into account to make the computational approach efficient.

  13. Anisotropic thermal expansion of a 3D metal–organic framework with hydrophilic and hydrophobic pores

    International Nuclear Information System (INIS)

    A 3D flexible metal–organic framework (MOF) with 1D hydrophilic and hydrophobic pores shows anisotropic thermal expansion with relatively large thermal expansion coefficient (αa=−21×10−6 K−1 and αc=79×10−6 K−1) between 133 K and 383 K. Temperature change gives deformation of both pores, which expand in diameter and elongate in length on cooling and vice versa. The thermally induced structural change should be derived from a unique framework topology like “lattice fence”. Silica accommodation changes not only the nature of the MOF but also thermal responsiveness of the MOF. Since the hydrophobic pores in the material are selectively blocked by the silica, the MOF with the silica is considered as a hydrophilic microporous material. Furthermore, inclusion of silica resulted in a drastic pore contraction in diameter and anisotropically changed the thermal responsiveness of the MOF. - Graphical abstract: A 3D metal–organic framework with hydrophilic and hydrophobic pores shows anisotropic thermal expansion behavior. The influence of silica filler in the hydrophobic pore was investigated. - Highlights: • Thermally induced structural change of a 3D MOF with a lattice fence topology was investigated. • The structural change was analyzed by synchrotron X-ray diffraction patterns. • Temperature change induces anisotropic thermal expansion/contraction of the MOF. • Silica inclusion anisotropically changes the thermal responsiveness of the MOF

  14. Anisotropic thermal expansion of a 3D metal–organic framework with hydrophilic and hydrophobic pores

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, Atsushi, E-mail: kondoa@cc.tuat.ac.jp; Maeda, Kazuyuki

    2015-01-15

    A 3D flexible metal–organic framework (MOF) with 1D hydrophilic and hydrophobic pores shows anisotropic thermal expansion with relatively large thermal expansion coefficient (α{sub a}=−21×10{sup −6} K{sup −1} and α{sub c}=79×10{sup −6} K{sup −1}) between 133 K and 383 K. Temperature change gives deformation of both pores, which expand in diameter and elongate in length on cooling and vice versa. The thermally induced structural change should be derived from a unique framework topology like “lattice fence”. Silica accommodation changes not only the nature of the MOF but also thermal responsiveness of the MOF. Since the hydrophobic pores in the material are selectively blocked by the silica, the MOF with the silica is considered as a hydrophilic microporous material. Furthermore, inclusion of silica resulted in a drastic pore contraction in diameter and anisotropically changed the thermal responsiveness of the MOF. - Graphical abstract: A 3D metal–organic framework with hydrophilic and hydrophobic pores shows anisotropic thermal expansion behavior. The influence of silica filler in the hydrophobic pore was investigated. - Highlights: • Thermally induced structural change of a 3D MOF with a lattice fence topology was investigated. • The structural change was analyzed by synchrotron X-ray diffraction patterns. • Temperature change induces anisotropic thermal expansion/contraction of the MOF. • Silica inclusion anisotropically changes the thermal responsiveness of the MOF.

  15. A 3D gravity and thermal model for the Barents Sea and Kara Sea

    Science.gov (United States)

    Klitzke, Peter; Sippel, Judith; Faleide, Jan Inge; Scheck-Wenderoth, Magdalena

    2016-08-01

    In the frame of this study, we investigate the lithosphere-scale 3D physical state of the Barents Sea and Kara Sea region. Therefore, we test an existing 3D structural model against the gravitational field by considering the heterogeneous upper mantle to further assess the structural and density configuration of the continental crystalline crust. The resulting 3D density configuration of the crust is discussed in terms of its relationships with the spatial distribution of tectonically different domains. In addition, it provides the base for a lithology-controlled parameterisation of the crust with thermal properties to calculate the 3D conductive thermal field. The deeper thermal field is controlled by the depth configuration of the lithosphere-asthenosphere boundary. Accordingly, deeper isotherms such as the 450 °C isotherm deepen from below the rifted SW Barents Sea towards the intracratonic basins of the eastern Barents Sea and Kara Sea, indicating an increase of the lithospheric strength in the same direction. Temperature measurements of the upper 800 m below the SW Barents Sea reveal an increased thermal gradient which cannot be reproduced by a steady-state 3D conductive model alone. Beside fault-induced fluid flow to be active there, an alternative scenario could involve a phase of subsidence long enough to increase the temperature of the upper 800 m, followed by an uplift and erosion phase that prevented the positive thermal anomaly to propagate towards larger depths. The final lithosphere-scale 3D model is the first to integrate the geological, density and thermal configuration of the entire Barents Sea and Kara Sea region and hence provides an ideal base for future thermomechanical studies addressing, for instance, questions on the present-day, past and future relationships between lithospheric strength and deformation.

  16. Accuracy evaluation of 3D lidar data from small UAV

    Science.gov (United States)

    Tulldahl, H. M.; Bissmarck, Fredrik; Larsson, Hâkan; Grönwall, Christina; Tolt, Gustav

    2015-10-01

    A UAV (Unmanned Aerial Vehicle) with an integrated lidar can be an efficient system for collection of high-resolution and accurate three-dimensional (3D) data. In this paper we evaluate the accuracy of a system consisting of a lidar sensor on a small UAV. High geometric accuracy in the produced point cloud is a fundamental qualification for detection and recognition of objects in a single-flight dataset as well as for change detection using two or several data collections over the same scene. Our work presented here has two purposes: first to relate the point cloud accuracy to data processing parameters and second, to examine the influence on accuracy from the UAV platform parameters. In our work, the accuracy is numerically quantified as local surface smoothness on planar surfaces, and as distance and relative height accuracy using data from a terrestrial laser scanner as reference. The UAV lidar system used is the Velodyne HDL-32E lidar on a multirotor UAV with a total weight of 7 kg. For processing of data into a geographically referenced point cloud, positioning and orientation of the lidar sensor is based on inertial navigation system (INS) data combined with lidar data. The combination of INS and lidar data is achieved in a dynamic calibration process that minimizes the navigation errors in six degrees of freedom, namely the errors of the absolute position (x, y, z) and the orientation (pitch, roll, yaw) measured by GPS/INS. Our results show that low-cost and light-weight MEMS based (microelectromechanical systems) INS equipment with a dynamic calibration process can obtain significantly improved accuracy compared to processing based solely on INS data.

  17. In Situ Thermal Generation of Silver Nanoparticles in 3D Printed Polymeric Structures

    Directory of Open Access Journals (Sweden)

    Erika Fantino

    2016-07-01

    Full Text Available Polymer nanocomposites have always attracted the interest of researchers and industry because of their potential combination of properties from both the nanofillers and the hosting matrix. Gathering nanomaterials and 3D printing could offer clear advantages and numerous new opportunities in several application fields. Embedding nanofillers in a polymeric matrix could improve the final material properties but usually the printing process gets more difficult. Considering this drawback, in this paper we propose a method to obtain polymer nanocomposites by in situ generation of nanoparticles after the printing process. 3D structures were fabricated through a Digital Light Processing (DLP system by disolving metal salts in the starting liquid formulation. The 3D fabrication is followed by a thermal treatment in order to induce in situ generation of metal nanoparticles (NPs in the polymer matrix. Comprehensive studies were systematically performed on the thermo-mechanical characteristics, morphology and electrical properties of the 3D printed nanocomposites.

  18. Estimation of the thermal conductivity of hemp based insulation material from 3D tomographic images

    Science.gov (United States)

    El-Sawalhi, R.; Lux, J.; Salagnac, P.

    2016-08-01

    In this work, we are interested in the structural and thermal characterization of natural fiber insulation materials. The thermal performance of these materials depends on the arrangement of fibers, which is the consequence of the manufacturing process. In order to optimize these materials, thermal conductivity models can be used to correlate some relevant structural parameters with the effective thermal conductivity. However, only a few models are able to take into account the anisotropy of such material related to the fibers orientation, and these models still need realistic input data (fiber orientation distribution, porosity, etc.). The structural characteristics are here directly measured on a 3D tomographic image using advanced image analysis techniques. Critical structural parameters like porosity, pore and fiber size distribution as well as local fiber orientation distribution are measured. The results of the tested conductivity models are then compared with the conductivity tensor obtained by numerical simulation on the discretized 3D microstructure, as well as available experimental measurements. We show that 1D analytical models are generally not suitable for assessing the thermal conductivity of such anisotropic media. Yet, a few anisotropic models can still be of interest to relate some structural parameters, like the fiber orientation distribution, to the thermal properties. Finally, our results emphasize that numerical simulations on 3D realistic microstructure is a very interesting alternative to experimental measurements.

  19. Outcome evaluation in shoulder surgery using 3D kinematics sensors

    OpenAIRE

    Coley, B.; Jolles, B.; Farron, A.; Bourgeois, A; Nussbaumer, F.; Pichonnaz, C.; Aminian, K.

    2007-01-01

    A new method of scoring systems for the functional assessment of the shoulder is presented. 3D accelerometers and gyroscopes attached on the humerus were used to differentiate a healthy from a painful shoulder. The method was first tested on 10 healthy volunteer subjects without any shoulder pathologies. Then, the system was tested on 10 patients with unilateral shoulder pathology (rotator cuff disease, osteoarthritis) before and after surgery (3, 6 months). To evalua...

  20. First vapor explosion calculations performed with MC3D thermal-hydraulic code

    Energy Technology Data Exchange (ETDEWEB)

    Brayer, C.; Berthoud, G. [CEA Centre d`Etudes de Grenoble, 38 (France). Direction des Reacteurs Nucleaires

    1998-01-01

    This paper presents the first calculations performed with the `explosion` module of the multiphase computer code MC3D, which is devoted to the fine fragmentation and explosion phase of a fuel coolant interaction. A complete description of the physical laws included in this module is given. The fragmentation models, taking into account two fragmentation mechanisms, a thermal one and an hydrodynamic one, are also developed here. Results to some calculations to test the numerical behavior of MC3D and to test the explosion models in 1D or 2D are also presented. (author)

  1. Three-dimensional (3-D) thermal investigation below high Alpine topography

    Science.gov (United States)

    Kohl, T.; Signorelli, S.; Rybach, L.

    2001-11-01

    The characteristics of severe topography in active mountain belts represent a special challenge for the evaluation of subsurface temperatures. These conditions require in particular a proper treatment of possible thermally relevant mechanisms. In the present analysis temperature data from depths of up to 1.5 km are investigated which have been collected at the intermediate "point-of-attack" in the framework of the new Alpine transverse (NEAT) project in central Switzerland for the construction of a 57 km long base tunnel. Specially designed temperature measurements were used in a 800 m deep shaft and along a 1200 m long access adit. Additional thermal information was provided by temperature logs from two nearby exploration boreholes and from laboratory measurements of various samples. For a detailed investigation of the temperature data a transient finite element (FE) model has been used which accounts for fluid and mass advection (uplift) as well as for climatic changes. The uplift and exhumation scenario assumed the surface to be in steady-state conditions. Special emphasis was given to structural effects like topography and anisotropy. The 3-D numerical model extends over an area of ˜ 20 km×20 km and includes Alpine high topographic relief with altitudes between 1500 and 3000 m a.s.l. Without modifying petrophysical parameters determined from laboratory measurements, all reliable temperature data could be nearly perfectly fitted by adjusting the two principal thermal boundary conditions at the surface and at the bottom. This study reveals that hydraulic influence is generally negligible at depths below ˜500 m which is in contrast to results from lower-dimensional methods such as 1-D Péclet analyses. Vertical heat flow variations are rather due to topographic than to hydraulic impact. Sensitivity studies highlight the importance of uplift in the central Swiss Alps and of local ground surface temperature (GST) distribution which both can influence the

  2. 3D structure and conductive thermal field of the Upper Rhine Graben

    Science.gov (United States)

    Freymark, Jessica; Sippel, Judith; Scheck-Wenderoth, Magdalena; Bär, Kristian; Stiller, Manfred; Fritsche, Johann-Gerhard; Kracht, Matthias

    2016-04-01

    The Upper Rhine Graben (URG) was formed as part of the European Cenozoic Rift System in a complex extensional setting. At present-day, it has a large socioeconomic relevance as it provides a great potential for geothermal energy production in Germany and France. For the utilisation of this energy resource it is crucial to understand the structure and the observed temperature anomalies in the rift basin. In the framework of the EU-funded "IMAGE" project (Integrated Methods for Advanced Geothermal Exploration), we apply a data-driven numerical modelling approach to quantify the processes and properties controlling the spatial distribution of subsurface temperatures. Typically, reservoir-scale numerical models are developed for predictions on the subsurface hydrothermal conditions and for reducing the risk of drilling non-productive geothermal wells. One major problem related to such models is setting appropriate boundary conditions that define, for instance, how much heat enters the reservoir from greater depths. Therefore, we first build a regional lithospheric-scale 3D structural model, which covers not only the entire URG but also adjacent geological features like the Black Forest and the Vosges Mountains. In particular, we use a multidisciplinary dataset (e.g. well data, seismic reflection data, existing structural models, gravity) to construct the geometries of the sediments, the crust and the lithospheric mantle that control the spatial distribution of thermal conductivity and radiogenic heat production and hence temperatures. By applying a data-based and lithology-dependent parameterisation of this lithospheric-scale 3D structural model and a 3D finite element method, we calculate the steady-state conductive thermal field for the entire region. Available measured temperatures (down to depths of up to 5 km) are considered to validate the 3D thermal model. We present major characteristics of the lithospheric-scale 3D structural model and results of the 3D

  3. Cookoff Response of PBXN-109: Material Characterization and ALE3D Thermal Predictions

    Energy Technology Data Exchange (ETDEWEB)

    McClelland, M A; Tran, T D; Cunningham, B J; Weese, R K; Maienschein, J L

    2001-05-29

    Materials properties measurements are made for the RDX-based explosive, PBXN-109, and initial ALE3D model predictions are given for the cookoff temperature in a U.S. Navy test. This work is part of an effort in the U.S. Navy and Department of Energy (DOE) laboratories to understand the thermal explosion behavior of this material. Benchmark cookoff experiments are being performed by the U.S. Navy to validate DOE materials models and computer codes. The ALE3D computer code can model the coupled thermal, mechanical, and chemical behavior of heating, ignition, and explosion in cookoff tests. In our application, a standard three-step step model is selected for the chemical kinetics. The strength behavior of the solid constituents is represented by a Steinberg-Guinan model while polynomial and gamma-law expressions are used for the Equation Of State (EOS) for the solid and gas species, respectively. Materials characterization measurements are given for thermal expansion, heat capacity, shear modulus, bulk modulus, and One-Dimensional-Time-to-Explosion (ODTX). These measurements and those of the other project participants are used to determine parameters in the ALE3D chemical, mechanical, and thermal models. Time-dependent, two-dimensional results are given for the temperature and material expansion. The results show predicted cookoff temperatures slightly higher than the measured values.

  4. Cookoff Response of PBXN-109: Material Characterization and ALE3D Thermal Predictions

    Energy Technology Data Exchange (ETDEWEB)

    McClelland, M A; Tran, T D; Cunningham, B J; Weese, R K; Maienschein, J L

    2001-08-21

    Materials properties measurements are made for the RDX-based explosive, PBXN-109, and initial ALE3D model predictions are given for the cookoff temperature in a U.S. Navy test. This work is part of an effort in the U.S. Navy and Department of Energy (DOE) laboratories to understand the thermal explosion behavior of this material. Benchmark cookoff experiments are being performed by the U.S. Navy to validate DOE materials models and computer codes. The ALE3D computer code can model the coupled thermal, mechanical, and chemical behavior of heating, ignition, and explosion in cookoff tests. In our application, a standard three-step step model is selected for the chemical kinetics. The strength behavior of the solid constituents is represented by a Steinberg-Guinan model while polynomial and gamma-law expressions are used for the Equation Of State (EOS) for the solid and gas species, respectively. Materials characterization measurements are given for thermal expansion, heat capacity, shear modulus, bulk modulus, and One-Dimensional-Time-to-Explosion (ODTX). These measurements and those of the other project participants are used to determine parameters in the ALE3D chemical, mechanical, and thermal models. Time-dependent, two-dimensional results are given for the temperature and material expansion. The results show predicted cookoff temperatures slightly higher than the measured values.

  5. Thermal characterization of a liquid resin for 3D printing using photothermal techniques

    Science.gov (United States)

    Jiménez-Pérez, José L.; Pincel, Pavel Vieyra; Cruz-Orea, Alfredo; Correa-Pacheco, Zormy N.

    2016-05-01

    Thermal properties of a liquid resin were studied by thermal lens spectrometry (TLS) and open photoacoustic cell (OPC), respectively. In the case of the TLS technique, the two mismatched mode experimental configuration was used with a He-Ne laser, as a probe beam and an Argon laser was used as the excitation source. The characteristic time constant of the transient thermal lens was obtained by fitting the theoretical expression to the experimental data in order to obtain the thermal diffusivity ( α) of the resin. On the other hand, the sample thermal effusivity ( e) was obtained by using the OPC technique. In this technique, an Argon laser was used as the excitation source and was operated at 514 nm with an output power of 30 mW. From the obtained thermal diffusivity ( α) and thermal effusivity ( e) values, the thermal conductivity ( k) and specific heat capacity per unit volume ( ρc) of resin were calculated through the relationships k = e( α)1/2 and ρc = e/( α)1/2. The obtained thermal parameters were compared with the thermal parameters of the literature. To our knowledge, the thermal characterization of resin has not been reported until now. The present study has applications in laser stereo-lithography to manufacture 3D printing pieces.

  6. Evaluating 3D-printed biomaterials as scaffolds for vascularized bone tissue engineering.

    Science.gov (United States)

    Wang, Martha O; Vorwald, Charlotte E; Dreher, Maureen L; Mott, Eric J; Cheng, Ming-Huei; Cinar, Ali; Mehdizadeh, Hamidreza; Somo, Sami; Dean, David; Brey, Eric M; Fisher, John P

    2015-01-01

    There is an unmet need for a consistent set of tools for the evaluation of 3D-printed constructs. A toolbox developed to design, characterize, and evaluate 3D-printed poly(propylene fumarate) scaffolds is proposed for vascularized engineered tissues. This toolbox combines modular design and non-destructive fabricated design evaluation, evaluates biocompatibility and mechanical properties, and models angiogenesis.

  7. Extreme low thermal conductivity in nanoscale 3D Si phononic crystal with spherical pores.

    Science.gov (United States)

    Yang, Lina; Yang, Nuo; Li, Baowen

    2014-01-01

    In this work, we propose a nanoscale three-dimensional (3D) Si phononic crystal (PnC) with spherical pores, which can reduce the thermal conductivity of bulk Si by a factor up to 10,000 times at room temperature. Thermal conductivity of Si PnCs depends on the porosity, for example, the thermal conductivity of Si PnCs with porosity 50% is 300 times smaller than that of bulk Si. The phonon participation ratio spectra demonstrate that more phonons are localized as the porosity increases. The thermal conductivity is insensitive to the temperature changes from room temperature to 1100 K. The extreme-low thermal conductivity could lead to a larger value of ZT than unity as the periodic structure affects very little the electric conductivity.

  8. Thermal-Aware Post Layout Voltage-Island Generation for 3D ICs

    Institute of Scientific and Technical Information of China (English)

    Ning Xu; Yu-Chun Ma; Jia Liu; Shou-Chun Tao

    2013-01-01

    To reduce the interconnect delay and improve the chip performance,three-dimensional (3D) chip emerged with the rapid increasing of chip integration and chip power density.Therefore,thermal issue is one of the critical challenges in 3D IC design due to the high power density.Multiple Supply Voltages (MSV) technique provides an efficient way to optimize power consumption which in turn may alleviate the hotspots.But the voltage assignment is limited not only by the performance constraints of the design,but also by the physical layout of circuit modules since the modules with the same voltage should be gathered to reduce the power-network routing resource.Especially in 3D designs,the optimization using MSV technique becomes even more complicated since the high temperature also influences the power consumption and delay on paths.In this paper,we address the voltage-island generation problem for MSV designs in 3D ICs based on a mixed integer linear programming (MILP) model.First,we propose a general MILP formulation for voltage-island generation to optimize thermal distribution as well as power-network routing resources while maintaining the whole chip performance.With the thermal-power interdependency,an iterative optimization approach is proposed to obtain the convergence.Experimental results show that our thermal-aware voltage-island generation approach can reduce the maximal on-chip temperature by 23.64% with a reasonable runtime and save the power-network routing resources by 16.71%.

  9. 3D thermal analysis of rectangular microscale inorganic light-emitting diodes in a pulsed operation

    Science.gov (United States)

    Cui, Y.; Bian, Z.; Li, Y.; Xing, Y.; Song, J.

    2016-10-01

    Microscale inorganic light-emitting diodes (µ-ILEDs) have attracted much attention due to their excellent performance in biointegrated applications such as optogenetics. The thermal behaviors of µ-ILEDs are critically important since a certain temperature increase may degrade the LED performance and cause tissue lesion. The µ-ILEDs in a pulsed operation offer an advantage in thermal management. In this paper, a 3D analytic model, as validated by finite element analysis, is developed to study the thermal response of rectangular µ-ILEDs in a pulsed operation. A scaling law for the maximum normalized temperature increase of rectangular µ-ILEDs in terms of non-dimensional parameters is established. The influences of geometric (i.e. shape factor) and loading parameters (e.g. duty cycle and period) on the temperature increase are systematically investigated. These results are very helpful in designing µ-ILEDs by providing guidelines to avoid adverse thermal effects.

  10. A 3D visible evaluation of landslide risk degree under integration of GIS and artificial intelligence

    Institute of Scientific and Technical Information of China (English)

    QIAO; Jianping; ZHU; Axing; CHEN; Yongbo; WANG; Rongxun

    2003-01-01

    Artificial intelligence has been used to obtain background factors (basic environmental factors) from landslide specialists. A 3D visible evaluation map may be charted by fuzzy evaluation, and the traditional plane map may be decoded into a 3D map by using factor weight from specialists system and technology of RS and GIS for quantitative sampling of these factors.

  11. Thermal hydraulic analysis for the Oregon State TRIGA reactor using RELAP5-3D

    International Nuclear Information System (INIS)

    Thermal hydraulic analyses have being conducted at Oregon State University (OSU) in support of the conversion of the OSU TRIGA reactor (OSTR) core from high-enriched uranium (HEU) to low-enriched uranium (LEU) fuel as part of the Reduced Enrichment for Research and Test Reactors program. The goals of the thermal hydraulic analyses were to calculate natural circulation flow rates, coolant temperatures and fuel temperatures as a function of core power for both the HEU and LEU cores; calculate peak values of fuel temperature, cladding temperature, surface heat flux as well as departure from nuclear boiling ratio (DNBR) for steady state and pulse operation; and perform accident analyses for the accident scenarios identified in the OSTR safety analysis report. RELAP5-3D Version 2.4.2 was implemented to develop a model for the thermal hydraulic study. The OSTR core conversion is planned to take place in late 2008. (author)

  12. Reconstructing the Thermal Sunyaev-Zel'dovich Effect in 3D

    CERN Document Server

    Pratten, Geraint

    2014-01-01

    The thermal Sunyaev-Zel'dovich (tSZ) effect is one of the most promising tools we have for probing the baryonic Universe. Unfortunately, the tSZ effect is defined as a line of sight projection of the thermal pressure fluctuations of free-electrons, compromising our ability to probe the thermal history of the Universe by smearing out the tSZ observables. This results in a loss of redshift information diminishing the power of tSZ observations. It is hoped that by cross-correlating the tSZ effect with external tracers we can recover a good fraction of the lost information. Weak lensing (WL) is thought to provide a relatively unbiased probe of the dark Universe in 3D with many upcoming WL surveys having sky coverage that overlaps with current tSZ surveys. Generalising the commonly used tomographic approach, we advocate the use of the spherical Fourier-Bessel (sFB) expansion as a means to perform a full analysis of cross-correlations between the projected (2D) tSZ Compton y-parameter maps and 3D WL-convergence kap...

  13. Thermal-hydraulic characteristics and performance of 3D wavy channel based printed circuit heat exchanger

    International Nuclear Information System (INIS)

    CFD study is done here to propose an efficient PCHE (Printed Circuit Heat Exchanger) model; used as a recuperator in International Thermonuclear Experimental Reactor (ITER). 3D steady state conjugate heat-transfer numerical simulations are done; considering the variation of thermo-physical properties as a function of temperature. Helium is used as a working fluid and alloy 617 as solid substrate. The study is done for various angle of bend (θ = 0°(straight), 5°, 10° and 15°) and Reynolds number (Re = 350, 700, 1400 and 2100). Various types of flow patterns, within one wavy-section, are presented to analyze thermal-hydraulic characteristics. Thermal hydraulic performance parameters are presented for the various wavy-sections as well as within a section; and for the complete PCHE model. Heat transfer enhancement as compared to pressure penalty is higher for the wavy channel; and increases with increasing Re and θ. Wavy as compared to plane channel based PCHE is demonstrated here to give better thermal-hydraulic performance. A detailed characteristics as well as performance-parameters for thermal hydraulics in a 3D wavy channel based PCHE model − not found in the literature − is presented here. - Highlights: • Studied effect of Reynolds number and angle of bend. • Analyzed thermal-hydraulic characteristics, by various types of flow pat-terns. • Demonstrated an increase in local heat flux due to change in the flow-direction. • Demonstrated better performance of wavy as compared to plane channel based PCHE. • Proposed correlation for friction factor and Nusselt number

  14. Evaluation of field development plans using 3-D reservoir modelling

    Energy Technology Data Exchange (ETDEWEB)

    Seifert, D.; Lewis, J.J.M. [Heriot-Watt Univ., Edinburgh (United Kingdom); Newbery, J.D.H. [Conoco, UK Ltd., Aberdeen (United Kingdom)] [and others

    1997-08-01

    Three-dimensional reservoir modelling has become an accepted tool in reservoir description and is used for various purposes, such as reservoir performance prediction or integration and visualisation of data. In this case study, a small Northern North Sea turbiditic reservoir was to be developed with a line drive strategy utilising a series of horizontal producer and injector pairs, oriented north-south. This development plan was to be evaluated and the expected outcome of the wells was to be assessed and risked. Detailed analyses of core, well log and analogue data has led to the development of two geological {open_quotes}end member{close_quotes} scenarios. Both scenarios have been stochastically modelled using the Sequential Indicator Simulation method. The resulting equiprobable realisations have been subjected to detailed statistical well placement optimisation techniques. Based upon bivariate statistical evaluation of more than 1000 numerical well trajectories for each of the two scenarios, it was found that the wells inclinations and lengths had a great impact on the wells success, whereas the azimuth was found to have only a minor impact. After integration of the above results, the actual well paths were redesigned to meet external drilling constraints, resulting in substantial reductions in drilling time and costs.

  15. Task-specific evaluation of 3D image interpolation techniques

    Science.gov (United States)

    Grevera, George J.; Udupa, Jayaram K.; Miki, Yukio

    1998-06-01

    Image interpolation is an important operation that is widely used in medical imaging, image processing, and computer graphics. A variety of interpolation methods are available in the literature. However, their systematic evaluation is lacking. At a previous meeting, we presented a framework for the task independent comparison of interpolation methods based on a variety of medical image data pertaining to different parts of the human body taken from different modalities. In this new work, we present an objective, task-specific framework for evaluating interpolation techniques. The task considered is how the interpolation methods influence the accuracy of quantification of the total volume of lesions in the brain of Multiple Sclerosis (MS) patients. Sixty lesion detection experiments coming from ten patient studies, two subsampling techniques and the original data, and 3 interpolation methods is presented along with a statistical analysis of the results. This work comprises a systematic framework for the task-specific comparison of interpolation methods. Specifically, the influence of three interpolation methods in MS lesion quantification is compared.

  16. A 3D Finite Element evaluation of the exophthalmia reduction

    CERN Document Server

    Luboz, V; Boutault, F; Swider, P; Payan, Y; Luboz, Vincent; Pedrono, Annaig; Boutault, Franck; Swider, Pascal; Payan, Yohan

    2003-01-01

    This paper presents a first evaluation of the feasibility of Finite Element modelling of the orbital decompression, in the context of exophthalmia. First simulations are carried out with data extracted from a patient TDM exam. Results seem to qualitatively validate the feasibility of the simulations, with a Finite Element analysis that converges and provides a backward movement of the ocular globe associated with displacements of the fat tissues through the sinuses. This FE model can help a surgeon for the planning of the exophthalmia reduction, and especially for the position and the size of the decompression hole. To get an estimation of the fat tissues volume affected by the surgery, an analytical model seems to provide quicker results for an equivalent efficiency.

  17. Sodium Experiments on Natural Circulation Decay Heat Removal and 3D Simulation of Plenum Thermal Hydraulics

    International Nuclear Information System (INIS)

    Natural circulation decay heat removal is one of the significant issues for fast reactor safety, especially in long term station blackout events. Several sodium experiments were carried out using a 7-subassembly core model for core thermal hydraulics under natural circulation conditions and for onset transients of natural circulation in a decay heat removal system (DHRS) including natural draft. Significant heat removal via inter-wrapper flow was confirmed in the experiments. Solidification of sodium in an air cooler is one of key issues in loss of heat sink events. Natural circulation characteristics under long-term decay heat removal were also obtained. Multi-dimensional phenomena, e.g., thermal stratification and bypass flow in plenums and/or heat exchangers, may influence the natural circulation. Thus, 3D simulation method was developed for entire region in the primary loop. Comparison of temperature distributions in a DHRS heat exchanger between experiment and analysis was done. (author)

  18. Framework for quantitative evaluation of 3D vessel segmentation approaches using vascular phantoms in conjunction with 3D landmark localization and registration

    Science.gov (United States)

    Wörz, Stefan; Hoegen, Philipp; Liao, Wei; Müller-Eschner, Matthias; Kauczor, Hans-Ulrich; von Tengg-Kobligk, Hendrik; Rohr, Karl

    2016-03-01

    We introduce a framework for quantitative evaluation of 3D vessel segmentation approaches using vascular phantoms. Phantoms are designed using a CAD system and created with a 3D printer, and comprise realistic shapes including branches and pathologies such as abdominal aortic aneurysms (AAA). To transfer ground truth information to the 3D image coordinate system, we use a landmark-based registration scheme utilizing fiducial markers integrated in the phantom design. For accurate 3D localization of the markers we developed a novel 3D parametric intensity model that is directly fitted to the markers in the images. We also performed a quantitative evaluation of different vessel segmentation approaches for a phantom of an AAA.

  19. Modeling and simulation of 3D thermal stresses of large-sized castings in solidification processes

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    When heavy machines and large scaled receiver system of communication equipment are manufactured, it always needs to produce large- sized steel castings, aluminum castings and etc. Some defects of hot cracking by thermal stress often appear during solidification process as these castings are produced, which results in failure of castings.Therefore predicting the effects of technological parameters for production of castings on the thermal stress during solidification process becomes an important means. In this paper, the mathematical models have been established and numerical calculation of temperature fields by using finite difference method (FDM) and then thermal stress fields by using finite element method (FEM) during solidification process of castings have been carried out. The technological parameters of production have been optimized by the results of calculation and the defects of hot cracking have been eliminated. Modeling and simulation of 3D thermal stress during solidification processes of large-sized castings provided a scientific basis, which promoted further development of advanced manufacturing technique.

  20. 3D perfused brain phantom for interstitial ultrasound thermal therapy and imaging: design, construction and characterization

    International Nuclear Information System (INIS)

    Thermal therapy has emerged as an independent modality of treating some tumors. In many clinics the hyperthermia, one of the thermal therapy modalities, has been used adjuvant to radio- or chemotherapy to substantially improve the clinical treatment outcomes. In this work, a methodology for building a realistic brain phantom for interstitial ultrasound low dose-rate thermal therapy of the brain is proposed. A 3D brain phantom made of the tissue mimicking material (TMM) had the acoustic and thermal properties in the 20–32 °C range, which is similar to that of a brain at 37 °C. The phantom had 10–11% by mass of bovine gelatin powder dissolved in ethylene glycol. The TMM sonicated at 1 MHz, 1.6 MHz and 2.5 MHz yielded the amplitude attenuation coefficients of 62  ±  1 dB m−1, 115  ±  4 dB m−1 and 175  ±  9 dB m−1, respectively. The density and acoustic speed determination at room temperature (∼24 °C) gave 1040  ±  40 kg m−3 and 1545  ±  44 m s−1, respectively. The average thermal conductivity was 0.532 W m−1 K−1. The T1 and T2 values of the TMM were 207  ±  4 and 36.2  ±  0.4 ms, respectively. We envisage the use of our phantom for treatment planning and for quality assurance in MRI based temperature determination. Our phantom preparation methodology may be readily extended to other thermal therapy technologies. (paper)

  1. 3D neutronic codes coupled with thermal-hydraulic system codes for PWR, and BWR and VVER reactors

    Energy Technology Data Exchange (ETDEWEB)

    Langenbuch, S.; Velkov, K. [GRS, Garching (Germany); Lizorkin, M. [Kurchatov-Institute, Moscow (Russian Federation)] [and others

    1997-07-01

    This paper describes the objectives of code development for coupling 3D neutronics codes with thermal-hydraulic system codes. The present status of coupling ATHLET with three 3D neutronics codes for VVER- and LWR-reactors is presented. After describing the basic features of the 3D neutronic codes BIPR-8 from Kurchatov-Institute, DYN3D from Research Center Rossendorf and QUABOX/CUBBOX from GRS, first applications of coupled codes for different transient and accident scenarios are presented. The need of further investigations is discussed.

  2. 3D coexisting modes of thermal convection in the faulted Lower Yarmouk Gorge

    Science.gov (United States)

    Magri, Fabien; Inbar, Nimrod; Möller, Peter; Raggad, Marwan; Rödiger, Tino; Rosenthal, Eliyahu; Siebert, Christian

    2016-04-01

    Numerical investigations of 3D modes of large-scale convection in faulted aquifers are presented with the aim to infer possible transport mechanisms supporting the formation of thermal springs in the Lower Yarmouk Gorge (LYG), at the border between Israel and Jordan. The transient finite elements models are based on a geological model of the LYG that introduces more realistic structural features of the basin, compared to previous existing models of the area (Magri et al., submitted). The sensitivity analysis of the fault permeability showed that faults cross-cutting the main regional flow direction allow groundwater to be driven laterally by convective forces within the fault planes. Therein thermal waters can either discharge along the fault traces or exit the fault through adjacent permeable aquifers. The location of springs can migrate with time, is not strictly constrained to the damage zones and reflects the interplay between the wavelength of the multicellular regime in the fault zone and the regional flow toward discharge areas in the lowlands. The results presented here suggest that in the LYG case, crossing flow paths result from the coexistence of fault convection, that can develop for example along NE-SW oriented faults within the Gorge, and additional flow fields that can be induced either by topography N-S gradients, e.g. perpendicular to the major axe of the Gorge, or by local thermal convection in permeable aquifers below Eocene aquiclude. The sensitivity analysis is consistent with the analytical solutions based on viscous-dependent Rayleigh theory. It indicates that in the LYG coexisting transport processes likely occur at fault hydraulic conductivity ranging between 2.3e-7 m/s and 9.3e- 7 m/s (i.e. 7 m/yr and 30 m/yr). The LYG numerical example and the associated Rayleigh analysis can be applied to study the onset of thermal convection and resulting flow patterns of any fractured hydrothermal basin. References Magri F, Möller S, Inbar N, M

  3. Evaluation of isocenter reproducibility in telemedicine of 3D-radiotherapy treatment planning

    Energy Technology Data Exchange (ETDEWEB)

    Hirota, Saeko; Tsujino, Kayoko; Kimura, Kouji; Takada, Yoshiki; Hishikawa, Yoshio; Kono, Michio [Hyogo Medical Center for Adults, Akashi (Japan); Soejima, Toshinori; Kodama, Akihisa

    2000-09-01

    To evaluate the utility in telemedicine of Three-Dimensional Radiotherapy Treatment Planning (tele-3D-RTP) and to examine the accuracy of isocenter reproducibility in its offline trial. CT data of phantoms and patients in the satellite hospital were transferred to our hospital via floppy-disk and 3D-radiotherapy plans were generated by 3D-RTP computer in our hospital. Profile data of CT and treatment beams in the satellite hospital were pre-installed into the computer. Tele-3D-RTPs were performed in 3 phantom plans and 14 clinical plans for 13 patients. Planned isocenters were well reproduced, especially in the immobilized head and neck/brain tumor cases, whose 3D-vector of aberration was 1.96{+-}1.38 (SD) mm. This teletherapy system is well applicable for practical use and can provides cost-reduction through sharing the resources of expensive equipment and radiation oncologists. (author)

  4. On Fundamental Evaluation Using Uav Imagery and 3d Modeling Software

    Science.gov (United States)

    Nakano, K.; Suzuki, H.; Tamino, T.; Chikatsu, H.

    2016-06-01

    Unmanned aerial vehicles (UAVs), which have been widely used in recent years, can acquire high-resolution images with resolutions in millimeters; such images cannot be acquired with manned aircrafts. Moreover, it has become possible to obtain a surface reconstruction of a realistic 3D model using high-overlap images and 3D modeling software such as Context capture, Pix4Dmapper, Photoscan based on computer vision technology such as structure from motion and multi-view stereo. 3D modeling software has many applications. However, most of them seem to not have obtained appropriate accuracy control in accordance with the knowledge of photogrammetry and/or computer vision. Therefore, we performed flight tests in a test field using an UAV equipped with a gimbal stabilizer and consumer grade digital camera. Our UAV is a hexacopter and can fly according to the waypoints for autonomous flight and can record flight logs. We acquired images from different altitudes such as 10 m, 20 m, and 30 m. We obtained 3D reconstruction results of orthoimages, point clouds, and textured TIN models for accuracy evaluation in some cases with different image scale conditions using 3D modeling software. Moreover, the accuracy aspect was evaluated for different units of input image—course unit and flight unit. This paper describes the fundamental accuracy evaluation for 3D modeling using UAV imagery and 3D modeling software from the viewpoint of close-range photogrammetry.

  5. STAR 3D nodal kinetics and thermal-hydraulic model for the Pennsylvania State TRIGA reactor

    International Nuclear Information System (INIS)

    A detailed three-dimensional (3D) time-dependent STAR nodal kinetics model coupled to a one-dimensional (1 D) thermal-hydraulics WIGL model has been developed to describe conservatively the peak power and pulse behavior of the Penn State University (PSU) Breazeale TRIGA reactor. This paper describes how the STAR model and its cross section data input was developed and benchmarked against actual TRIGA pulse experiments. Different core configurations (i.e., different core loading patterns, and with/without the TRIGA core next to the D20 tank) were used for several TRIGA pulse tests with different reactivity insertion worths (1.5$, 2.0$ , 2.5$). This paper shows that the STAR nodal kinetics code adequately simulates TRIGA pulses when group constants are generated from physics codes (i.e., WIMS-D4) that can accurately model the TRIGA uranium-zirconium-hydride fuel. (author)

  6. Closed-loop high-speed 3D thermal probe nanolithography

    Science.gov (United States)

    Knoll, A. W.; Zientek, M.; Cheong, L. L.; Rawlings, C.; Paul, P.; Holzner, F.; Hedrick, J. L.; Coady, D. J.; Allen, R.; Dürig, U.

    2014-03-01

    Thermal Scanning Probe Lithography (tSPL) is an AFM based patterning technique, which uses heated tips to locally evaporate organic resists such as molecular glasses [1] or thermally sensitive polymers.[2][3] Organic resists offer the versatility of the lithography process known from the CMOS environment and simultaneously ensure a highly stable and low wear tip-sample contact due to the soft nature of the resists. Patterning quality is excellent up to a resolution of sub 15 nm,[1] at linear speeds of up to 20 mm/s and pixel rates of up to 500 kHz.[4] The patterning depth is proportional to the applied force which allows for the creation of 3-D profiles in a single patterning run.[2] In addition, non-destructive imaging can be done at pixel rates of more than 500 kHz.[4] If the thermal stimulus for writing the pattern is switched off the same tip can be used to record the written topography with Angstrom depth resolution. We utilize this unique feature of SPL to implement an efficient control system for reliable patterning at high speed and high resolution. We combine the writing and imaging process in a single raster scan of the surface. In this closed loop lithography (CLL) approach, we use the acquired data to optimize the writing parameters on the fly. Excellent control is in particular important for an accurate reproduction of complex 3D patterns. These novel patterning capabilities are equally important for a high quality transfer of two-dimensional patterns into the underlying substrate. We utilize an only 3-4 nm thick SiOx hardmask to amplify the 8±0.5 nm deep patterns created by tSPL into a 50 nm thick transfer polymer. The structures in the transfer polymer can be used to create metallic lines by a lift-off process or to further process the pattern into the substrate. Here we demonstrate the fabrication of 27 nm wide lines and trenches 60 nm deep into the Silicon substrate.[5] In addition, the combined read and write approach ensures that the lateral

  7. Network level pavement evaluation with 1 mm 3D survey system

    Directory of Open Access Journals (Sweden)

    Kelvin C.P. Wang

    2015-12-01

    Full Text Available The latest iteration of PaveVision3D Ultra can obtain true 1 mm resolution 3D data at full-lane coverage in all 3 directions at highway speed up to 60 mph. This paper introduces the PaveVision3D Ultra technology for rapid network level pavement survey on approximately 1280 center miles of Oklahoma interstate highways. With sophisticated automated distress analyzer (ADA software interface, the collected 1 mm 3D data provide Oklahoma Department of Transportation (ODOT with comprehensive solutions for automated evaluation of pavement surface including longitudinal profile for roughness, transverse profile for rutting, predicted hydroplaning speed for safety analysis, and cracking and various surface defects for distresses. The pruned exact linear time (PELT method, an optimal partitioning algorithm, is implemented to identify change points and dynamically determine homogeneous segments so as to assist ODOT effectively using the available 1 mm 3D pavement surface condition data for decision-making. The application of 1 mm 3D laser imaging technology for network survey is unprecedented. This innovative technology allows highway agencies to access its options in using the 1 mm 3D system for its design and management purposes, particularly to meet the data needs for pavement management system (PMS, pavement ME design and highway performance monitoring system (HPMS.

  8. Evaluation of Model Recognition for Grammar-Based Automatic 3d Building Model Reconstruction

    Science.gov (United States)

    Yu, Qian; Helmholz, Petra; Belton, David

    2016-06-01

    In recent years, 3D city models are in high demand by many public and private organisations, and the steadily growing capacity in both quality and quantity are increasing demand. The quality evaluation of these 3D models is a relevant issue both from the scientific and practical points of view. In this paper, we present a method for the quality evaluation of 3D building models which are reconstructed automatically from terrestrial laser scanning (TLS) data based on an attributed building grammar. The entire evaluation process has been performed in all the three dimensions in terms of completeness and correctness of the reconstruction. Six quality measures are introduced to apply on four datasets of reconstructed building models in order to describe the quality of the automatic reconstruction, and also are assessed on their validity from the evaluation point of view.

  9. Embodied collaboration support system for 3D shape evaluation in virtual space

    Science.gov (United States)

    Okubo, Masashi; Watanabe, Tomio

    2005-12-01

    Collaboration mainly consists of two tasks; one is each partner's task that is performed by the individual, the other is communication with each other. Both of them are very important objectives for all the collaboration support system. In this paper, a collaboration support system for 3D shape evaluation in virtual space is proposed on the basis of both studies in 3D shape evaluation and communication support in virtual space. The proposed system provides the two viewpoints for each task. One is the viewpoint of back side of user's own avatar for the smooth communication. The other is that of avatar's eye for 3D shape evaluation. Switching the viewpoints satisfies the task conditions for 3D shape evaluation and communication. The system basically consists of PC, HMD and magnetic sensors, and users can share the embodied interaction by observing interaction between their avatars in virtual space. However, the HMD and magnetic sensors, which are put on the users, would restrict the nonverbal communication. Then, we have tried to compensate the loss of nodding of partner's avatar by introducing the speech-driven embodied interactive actor InterActor. Sensory evaluation by paired comparison of 3D shapes in the collaborative situation in virtual space and in real space and the questionnaire are performed. The result demonstrates the effectiveness of InterActor's nodding in the collaborative situation.

  10. 3D thermal analysis of a permanent magnet motor with cooling fans

    Institute of Scientific and Technical Information of China (English)

    Zheng TAN; Xue-guan SONG; Bing JI; Zheng LIU; Ji-en MA; Wen-ping CAO

    2015-01-01

    Overheating of permanent magnet (PM) machines has become a major technical challenge as it gives rise to magnet demagnetization, degradation of insulation materials, and loss of motor efficiency. This paper proposes a state-of-the-art cooling system for an axial flux permanent magnet (AFPM) machine with the focus on its structural optimization. A computational fluid dynamics (CFD) simulation with thermal consideration has been shown to be an efficient approach in the literature and is thus employed in this work. Meanwhile, a simplified numerical approach to the AFPM machine with complex configuration in 3D consisting of conduction, forced convection, and conjugate heat transfer is taken as a case study. Different simplification meth-ods (including configuration and working conditions) and two optimized fans for forced convection cooling are designed and installed on the AFPM machine and compared to a natural convection cooling system. The results show that the proposed ap-proach is effective for analyzing the thermal performance of a complex AFPM machine and strikes a balance between reasona-ble simplification, accuracy, and computational resource.%目的:提出一种适合永磁电机的冷却系统设计方案,降低电机本体温度。  创新点:提出一种适合永磁电机热分析的CFD仿真模型。  方法:采用计算流体动力学方法对包含冷却风扇的永磁电机进行空间三维热力学分析和优化设计。  结论:本文提出并优化后的冷却风扇可有效降低永磁电机的最高和平均温度。

  11. FLOW3D model for below-core thermal mixing in the Oconee pressurised water reactor

    International Nuclear Information System (INIS)

    The computational fluid dynamics code FLOW3D is being used to develop a model for calculating the mixing of cold leg flows inside the vessel of a pressurised water reactor. To assess the capabilities of the model, a simulation was made of a thermal mixing test at the Oconee-1 Nuclear Station. The test measured temperature deviations at the core inlet produced by an imposed temperature difference between cold legs. Both the tests results and the simulation showed that most of the cold leg flows arrive unmixed at the core inlet. However, the simulation was unable to reproduce the asymmetric irregularities observed in the core inlet temperature distribution, and consequently the degree of mixing was under-predicted. Various sensitivity studies were carried out on the model, but these did not reveal the source of the asymmetry. It was therefore concluded that the asymmetry source was outside the scope of the model, but the model was nevertheless able to make plausible but pessimistic estimates of mixing. (author)

  12. Revitalizing the Space Shuttle's Thermal Protection System with Reverse Engineering and 3D Vision Technology

    Science.gov (United States)

    Wilson, Brad; Galatzer, Yishai

    2008-01-01

    The Space Shuttle is protected by a Thermal Protection System (TPS) made of tens of thousands of individually shaped heat protection tile. With every flight, tiles are damaged on take-off and return to earth. After each mission, the heat tiles must be fixed or replaced depending on the level of damage. As part of the return to flight mission, the TPS requirements are more stringent, leading to a significant increase in heat tile replacements. The replacement operation requires scanning tile cavities, and in some cases the actual tiles. The 3D scan data is used to reverse engineer each tile into a precise CAD model, which in turn, is exported to a CAM system for the manufacture of the heat protection tile. Scanning is performed while other activities are going on in the shuttle processing facility. Many technicians work simultaneously on the space shuttle structure, which results in structural movements and vibrations. This paper will cover a portable, ultra-fast data acquisition approach used to scan surfaces in this unstable environment.

  13. Interface requirements to couple thermal-hydraulic codes to 3D neutronic codes

    Energy Technology Data Exchange (ETDEWEB)

    Langenbuch, S.; Austregesilo, H.; Velkov, K. [GRS, Garching (Germany)] [and others

    1997-07-01

    The present situation of thermalhydraulics codes and 3D neutronics codes is briefly described and general considerations for coupling of these codes are discussed. Two different basic approaches of coupling are identified and their relative advantages and disadvantages are discussed. The implementation of the coupling for 3D neutronics codes in the system ATHLET is presented. Meanwhile, this interface is used for coupling three different 3D neutronics codes.

  14. Evaluation and assessment of the seismic responses of 3-D base-isolated structures

    Energy Technology Data Exchange (ETDEWEB)

    Hueffmann, G.K.; Sutton, W.T. [GERB Vibration Control Systems, Inc., Westmont, IL (United States)

    1995-12-01

    The 1994 Northridge earthquake offered the opportunity to evaluate and assess the seismic response of several base-isolated buildings. Assessment of 2-D base isolation is straightforward comparing separately the uncoupled horizontal and vertical building motions to the corresponding ground motions. With 3-D systems characterized by low vertical natural frequencies, the system assessment must include rocking of the structure. Neglecting this consideration leads to an erroneous conclusion that the system greatly amplifies vertical ground accelerations. The paper evaluates the seismic response of a 3-D base-isolated building as compared to the same structure on a 2-D system. The paper also shows that the vertical accelerations measured at extreme locations in the building on a 3-D base-isolation system develop mainly from rocking responses to the horizontal ground motion.

  15. Role of 3-D Conventional Angiography In Evaluation of Intra Carnial Aneurysms

    Directory of Open Access Journals (Sweden)

    Ahmed M Bassiouny*, Maher M Arafa*, Sameh M Abdelwahab*,

    2013-04-01

    Full Text Available Introduction: intracranial aneurysms are pathological enlargement of the brain arteries that are most commonly located in the circle of Willis. Intracranial aneurysms are relatively common with a prevalence of approximately 4%. The real danger of aneurysms is subarachnoid hemorrhage. 3D digital subtraction angiography has become a critical imaging tool in neuroradiology allowing for the visualization of detailed cerebral vasculature prior to any intervention. Aim of the work: The aim of this work is to evaluate the diagnostic performance of 3D conventional angiography in the evaluation of intracranial aneurysms compared with the conventional cerebral angiography. Methods: The studied group included 20 patients (5 men and 15 women with subarachnoid hemorrhage or known to have cerebral aneurysms. All patients were subjected to conventional cerebral angiography and 3D cerebral angiography, using C-arm (Toshiba rotational technique.Results: 3D digital subtraction angiography is superior to conventional digital subtraction angiography in 100% of the cases 3D imaging revealed the proper aneurysmal shape, size, precise assessment of its neck and relation to the surrounding vessels. Conclusion: Three-dimensional DSA improves the detection and delineation of intracranial aneurysms

  16. International training program: 3D S.UN.COP - Scaling, uncertainty and 3D thermal-hydraulics/neutron-kinetics coupled codes seminar

    International Nuclear Information System (INIS)

    Thermal-hydraulic system computer codes are extensively used worldwide for analysis of nuclear facilities by utilities, regulatory bodies, nuclear power plant designers and vendors, nuclear fuel companies, research organizations, consulting companies, and technical support organizations. The computer code user represents a source of uncertainty that can influence the results of system code calculations. This influence is commonly known as the 'user effect' and stems from the limitations embedded in the codes as well as from the limited capability of the analysts to use the codes. Code user training and qualification is an effective means for reducing the variation of results caused by the application of the codes by different users. This paper describes a systematic approach to training code users who, upon completion of the training, should be able to perform calculations making the best possible use of the capabilities of best estimate codes. In other words, the program aims at contributing towards solving the problem of user effect. The 3D S.UN.COP 2005 (Scaling, Uncertainty and 3D COuPled code calculations) seminar has been organized by University of Pisa and University of Zagreb as follow-up of the proposal to IAEA for the Permanent Training Course for System Code Users (D'Auria, 1998). It was recognized that such a course represented both a source of continuing education for current code users and a means for current code users to enter the formal training structure of a proposed 'permanent' stepwise approach to user training. The seminar-training was successfully held with the participation of 19 persons coming from 9 countries and 14 different institutions (universities, vendors, national laboratories and regulatory bodies). More than 15 scientists were involved in the organization of the seminar, presenting theoretical aspects of the proposed methodologies and holding the training and the final examination. A certificate (LA Code User grade) was released

  17. Evaluation of low-dose limits in 3D-2D rigid registration for surgical guidance

    Science.gov (United States)

    Uneri, A.; Wang, A. S.; Otake, Y.; Kleinszig, G.; Vogt, S.; Khanna, A. J.; Gallia, G. L.; Gokaslan, Z. L.; Siewerdsen, J. H.

    2014-09-01

    An algorithm for intensity-based 3D-2D registration of CT and C-arm fluoroscopy is evaluated for use in surgical guidance, specifically considering the low-dose limits of the fluoroscopic x-ray projections. The registration method is based on a framework using the covariance matrix adaptation evolution strategy (CMA-ES) to identify the 3D patient pose that maximizes the gradient information similarity metric. Registration performance was evaluated in an anthropomorphic head phantom emulating intracranial neurosurgery, using target registration error (TRE) to characterize accuracy and robustness in terms of 95% confidence upper bound in comparison to that of an infrared surgical tracking system. Three clinical scenarios were considered: (1) single-view image + guidance, wherein a single x-ray projection is used for visualization and 3D-2D guidance; (2) dual-view image + guidance, wherein one projection is acquired for visualization, combined with a second (lower-dose) projection acquired at a different C-arm angle for 3D-2D guidance; and (3) dual-view guidance, wherein both projections are acquired at low dose for the purpose of 3D-2D guidance alone (not visualization). In each case, registration accuracy was evaluated as a function of the entrance surface dose associated with the projection view(s). Results indicate that images acquired at a dose as low as 4 μGy (approximately one-tenth the dose of a typical fluoroscopic frame) were sufficient to provide TRE comparable or superior to that of conventional surgical tracking, allowing 3D-2D guidance at a level of dose that is at most 10% greater than conventional fluoroscopy (scenario #2) and potentially reducing the dose to approximately 20% of the level in a conventional fluoroscopically guided procedure (scenario #3).

  18. An Exploratory Evaluation of User Interfaces for 3D Audio Mixing

    DEFF Research Database (Denmark)

    Gelineck, Steven; Korsgaard, Dannie Michael

    2015-01-01

    The paper presents an exploratory evaluation comparing different versions of a mid-air gesture based interface for mixing 3D audio exploring: (1) how such an interface generally compares to a more traditional physical interface, (2) methods for grabbing/releasing audio channels in mid-air and (3...

  19. Ground truth evaluation of computer vision based 3D reconstruction of synthesized and real plant images

    DEFF Research Database (Denmark)

    Nielsen, Michael; Andersen, Hans Jørgen; Slaughter, David;

    2007-01-01

    There is an increasing interest in using 3D computer vision in precision agriculture. This calls for better quantitative evaluation and understanding of computer vision methods. This paper proposes a test framework using ray traced crop scenes that allows in-depth analysis of algorithm performanc...

  20. An Interactive 3D Virtual Anatomy Puzzle for Learning and Simulation - Initial Demonstration and Evaluation.

    Science.gov (United States)

    Messier, Erik; Wilcox, Jascha; Dawson-Elli, Alexander; Diaz, Gabriel; Linte, Cristian A

    2016-01-01

    To inspire young students (grades 6-12) to become medical practitioners and biomedical engineers, it is necessary to expose them to key concepts of the field in a way that is both exciting and informative. Recent advances in medical image acquisition, manipulation, processing, visualization, and display have revolutionized the approach in which the human body and internal anatomy can be seen and studied. It is now possible to collect 3D, 4D, and 5D medical images of patient specific data, and display that data to the end user using consumer level 3D stereoscopic display technology. Despite such advancements, traditional 2D modes of content presentation such as textbooks and slides are still the standard didactic equipment used to teach young students anatomy. More sophisticated methods of display can help to elucidate the complex 3D relationships between structures that are so often missed when viewing only 2D media, and can instill in students an appreciation for the interconnection between medicine and technology. Here we describe the design, implementation, and preliminary evaluation of a 3D virtual anatomy puzzle dedicated to helping users learn the anatomy of various organs and systems by manipulating 3D virtual data. The puzzle currently comprises several components of the human anatomy and can be easily extended to include additional organs and systems. The 3D virtual anatomy puzzle game was implemented and piloted using three display paradigms - a traditional 2D monitor, a 3D TV with active shutter glass, and the DK2 version Oculus Rift, as well as two different user interaction devices - a space mouse and traditional keyboard controls. PMID:27046584

  1. 3D thermal history and maturity modelling of the Levant Basin and Margin

    Science.gov (United States)

    Daher, Samer Bou; Ducros, Mathieu; Michel, Pauline; Nader, Fadi H.; Littke, Ralf

    2015-04-01

    The gas discoveries recorded in the Levant Basin in the last decade have redirected the industrial and academic communities' interest to this frontier basin and its surroundings. The reported gas in Miocene reservoirs has been assumed to be derived from biogenic sources, although little data has been published so far. The thickness of the sedimentary column and the presence of direct hydrocarbon indicators (DHI) observed in the seismic data suggest the presence of promising prospective thermogenic petroleum systems in deeper intervals in the Levant Basin and along its Margin. In this study we present a large scale 3D thermal history and maturity model of the Levant Basin and Margin, integrating all available calibration data, source rock information collected from onshore Lebanon, and published data. In the first part we will present the main input and assumptions that were made in terms of thicknesses, lithologies, and boundary conditions. In the second part we will discuss the analysed source rocks, their petroleum generation potential and their kinetics. In the third part we will present modelling results including depth maps for key isotherms in addition to transformation ratio and vitrinite reflectance maps for proven and speculative source rocks at different time steps. This will provide a comprehensive assessment of the potential thermogenic petroleum systems in the study area, and allow us to illustrate and discuss the differences between the basinal, marginal, and onshore part of the study area as well as the potential of the northern vis a vis the southern offshore Levant Basin. This model will also allow us to analyse the sensitivity of the system to the various poorly constrained parameters in frontier basins (e.g. crustal thickness, rifting phases, lithologies) and thus identify the most critical data to be collected for future exploration and de-risking strategies.

  2. Soft Tissue Stability around Single Implants Inserted to Replace Maxillary Lateral Incisors: A 3D Evaluation

    Science.gov (United States)

    Mangano, F. G.; Picciocchi, G.; Park, K. B.

    2016-01-01

    Purpose. To evaluate the soft tissue stability around single implants inserted to replace maxillary lateral incisors, using an innovative 3D method. Methods. We have used reverse-engineering software for the superimposition of 3D surface models of the dentogingival structures, obtained from intraoral scans of the same patients taken at the delivery of the final crown (S1) and 2 years later (S2). The assessment of soft tissues changes was performed via calculation of the Euclidean surface distances between the 3D models, after the superimposition of S2 on S1; colour maps were used for quantification of changes. Results. Twenty patients (8 males, 12 females) were selected, 10 with a failing/nonrestorable lateral incisor (test group: immediate placement in postextraction socket) and 10 with a missing lateral incisor (control group: conventional placement in healed ridge). Each patient received one immediately loaded implant (Anyridge®, Megagen, Gyeongbuk, South Korea). The superimposition of the 3D surface models taken at different times (S2 over S1) revealed a mean (±SD) reduction of 0.057 mm (±0.025) and 0.037 mm (±0.020) for test and control patients, respectively. This difference was not statistically significant (p = 0.069). Conclusions. The superimposition of the 3D surface models revealed an excellent peri-implant soft tissue stability in both groups of patients, with minimal changes registered along time. PMID:27298621

  3. On the evaluation of photogrammetric methods for dense 3D surface reconstruction in a metrological context

    Science.gov (United States)

    Toschi, I.; Capra, A.; De Luca, L.; Beraldin, J.-A.; Cournoyer, L.

    2014-05-01

    This paper discusses a methodology to evaluate the accuracy of recently developed image-based 3D modelling techniques. So far, the emergence of these novel methods has not been supported by the definition of an internationally recognized standard which is fundamental for user confidence and market growth. In order to provide an element of reflection and solution to the different communities involved in 3D imaging, a promising approach is presented in this paper for the assessment of both metric quality and limitations of an open-source suite of tools (Apero/MicMac), developed for the extraction of dense 3D point clouds from a set of unordered 2D images. The proposed procedural workflow is performed within a metrological context, through inter-comparisons with "reference" data acquired with two hemispherical laser scanners, one total station, and one laser tracker. The methodology is applied to two case studies, designed in order to analyse the software performances in dealing with both outdoor and environmentally controlled conditions, i.e. the main entrance of Cathédrale de la Major (Marseille, France) and a custom-made scene located at National Research Council of Canada 3D imaging Metrology Laboratory (Ottawa). Comparative data and accuracy evidence produced for both tests allow the study of some key factors affecting 3D model accuracy.

  4. 3D evaluation of palatal rugae for human identification using digital study models

    Science.gov (United States)

    Taneva, Emilia D.; Johnson, Andrew; Viana, Grace; Evans, Carla A.

    2015-01-01

    Background: While there is literature suggesting that the palatal rugae could be used for human identification, most of these studies use two-dimensional (2D) approach. Aim: The aims of this study were to evaluate palatal ruga patterns using three-dimensional (3D) digital models; compare the most clinically relevant digital model conversion techniques for identification of the palatal rugae; develop a protocol for overlay registration; determine changes in palatal ruga individual patterns through time; and investigate the efficiency and accuracy of 3D matching processes between different individuals’ patterns. Material and Methods: Five cross sections in the anteroposterior dimension and four cross sections in the transverse dimension were computed which generated 18 2D variables. In addition, 13 3D variables were defined: The posterior point of incisive papilla (IP), and the most medial and lateral end points of the palatal rugae (R1MR, R1ML, R1LR, R1LL, R2MR, R2ML, R2LR, R2LL, R3MR, R3ML, R3LR, and R3LL). The deviation magnitude for each variable was statistically analyzed in this study. Five different data sets with the same 31 landmarks were evaluated in this study. Results: The results demonstrated that 2D images and linear measurements in the anteroposterior and transverse dimensions were not sufficient for comparing different digital model conversion techniques using the palatal rugae. 3D digital models proved to be a highly effective tool in evaluating different palatal ruga patterns. The 3D landmarks showed no statistically significant mean differences over time or as a result of orthodontic treatment. No statistically significant mean differences were found between different digital model conversion techniques, that is, between OrthoCAD™ and Ortho Insight 3D™, and between Ortho Insight 3D™ and the iTero® scans, when using 12 3D palatal rugae landmarks for comparison. Conclusion: Although 12 palatal 3D landmarks could be used for human

  5. 3D evaluation of palatal rugae for human identification using digital study models

    Directory of Open Access Journals (Sweden)

    Emilia D Taneva

    2015-01-01

    Full Text Available Background: While there is literature suggesting that the palatal rugae could be used for human identification, most of these studies use two-dimensional (2D approach. Aim: The aims of this study were to evaluate palatal ruga patterns using three-dimensional (3D digital models; compare the most clinically relevant digital model conversion techniques for identification of the palatal rugae; develop a protocol for overlay registration; determine changes in palatal ruga individual patterns through time; and investigate the efficiency and accuracy of 3D matching processes between different individuals′ patterns. Material and Methods: Five cross sections in the anteroposterior dimension and four cross sections in the transverse dimension were computed which generated 18 2D variables. In addition, 13 3D variables were defined: The posterior point of incisive papilla (IP, and the most medial and lateral end points of the palatal rugae (R1MR, R1ML, R1LR, R1LL, R2MR, R2ML, R2LR, R2LL, R3MR, R3ML, R3LR, and R3LL. The deviation magnitude for each variable was statistically analyzed in this study. Five different data sets with the same 31 landmarks were evaluated in this study. Results: The results demonstrated that 2D images and linear measurements in the anteroposterior and transverse dimensions were not sufficient for comparing different digital model conversion techniques using the palatal rugae. 3D digital models proved to be a highly effective tool in evaluating different palatal ruga patterns. The 3D landmarks showed no statistically significant mean differences over time or as a result of orthodontic treatment. No statistically significant mean differences were found between different digital model conversion techniques, that is, between OrthoCAD™ and Ortho Insight 3D™, and between Ortho Insight 3D™ and the iTero; scans, when using 12 3D palatal rugae landmarks for comparison. Conclusion: Although 12 palatal 3D landmarks could be used for

  6. Evaluation of cartilage surface injuries using 3D-double echo steady state (3D-DESS): Effect of changing flip angle from 40 deg to 90 deg

    Energy Technology Data Exchange (ETDEWEB)

    Moriya, Susumu; Yokobayashi, Tsuneo; Ishikawa, Mitsunori (Ishikawa Clinic, Kyoto (Japan)), email: smoyari@yahoo.co.jp; Miki, Yukio (Dept. of Radiology, Osaka City Univ. Graduate School of Medicine, Osaka (Japan)); Kanagaki, Mitsunori; Yamamoto, Akira (Dept. of Diagnostic Imaging and Nuclear Medicine, Kyoto Univ., Kyoto (Japan)); Okudaira, Shuzo (Dept. of Orthopaedics, Kyoto Police Hospital, Kyoto (Japan)); Nakamura, Shinichiro (Center for Musculoskeletal Research, Univ. of Tennessee, Knoxville, TN (United States))

    2011-12-15

    Background. In magnetic resonance imaging (MRI) with 3D-double-echo steady-state (3D-DESS) sequences, the cartilage-synovial fluid contrast is reported to be better with a flip angle of 90 deg than with the conventional flip angle of 40 deg, and the detection rate of knee cartilage injury may be improved. Purpose. To compare the diagnostic performance and certainty of diagnosis with 3D-DESS images made using two flip angle settings, 40 deg and 90 deg, for knee cartilage surface lesions of Grade 2 or above confirmed by arthroscopy. Material and Methods. Images were obtained with 3D-DESS flip angles of 40 deg and 90 deg at 1.0T in 13 consecutive patients (2 men, 11 women, age range 18-68 years) evaluated for superficial cartilage injury by arthroscopy. Two radiologists classified the presence or absence of cartilage damage of >=Grade 2 as 'positive (p)' or 'negative (n)', respectively. The rate of agreement with arthroscopic diagnosis was then examined, and the diagnostic performance compared. Diagnostic confidence was assessed scoring the presence or absence of cartilage damage into three categories: 3 = can diagnose with absolute confidence; 2 = can diagnose with a level of certainty as probably present or probably absent; and 1 = cannot make a diagnosis. Results. In a comparison of the rate of agreement between diagnosis by 3D-DESS images and arthroscopy, the rate of agreement was significantly higher and diagnostic performance was better in 90 deg images for the medial femoral condyle only. Diagnostic confidence was significantly better with 90 deg flip angle images than with 40 deg flip angle images for all six cartilage surfaces. Conclusion. In evaluating knee cartilage surface lesions with 3D-DESS sequences, a flip angle setting of 90 deg is more effective than the conventional setting of 40 deg

  7. Applicability of RELAP5-3D for Thermal-Hydraulic Analyses of a Sodium-Cooled Actinide Burner Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    C. B. Davis

    2006-07-01

    The Actinide Burner Test Reactor (ABTR) is envisioned as a sodium-cooled, fast reactor that will burn the actinides generated in light water reactors to reduce nuclear waste and ease proliferation concerns. The RELAP5-3D computer code is being considered as the thermal-hydraulic system code to support the development of the ABTR. An evaluation was performed to determine the applicability of RELAP5-3D for the analysis of a sodium-cooled fast reactor. The applicability evaluation consisted of several steps, including identifying the important transients and phenomena expected in the ABTR, identifying the models and correlations that affect the code’s calculation of the important phenomena, and evaluating the applicability of the important models and correlations for calculating the important phenomena expected in the ABTR. The applicability evaluation identified code improvements and additional models needed to simulate the ABTR. The accuracy of the calculated thermodynamic and transport properties for sodium was also evaluated.

  8. A Novel 3D Thermal Impedance Model for High Power Modules Considering Multi-layer Thermal Coupling and Different Heating/Cooling Conditions

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2015-01-01

    accurate temperature estimation either vertically or horizontally inside the power devices is still hard to identify. This paper investigates the thermal behavior of high power module in various operating conditions by means of Finite Element Method (FEM). A novel 3D thermal impedance network considering...

  9. Evaluating 3D registration of CT-scan images using crest lines

    Science.gov (United States)

    Ayache, Nicholas; Gueziec, Andre P.; Thirion, Jean-Philippe; Gourdon, A.; Knoplioch, Jerome

    1993-06-01

    We consider the issue of matching 3D objects extracted from medical images. We show that crest lines computed on the object surfaces correspond to meaningful anatomical features, and that they are stable with respect to rigid transformations. We present the current chain of algorithmic modules which automatically extract the major crest lines in 3D CT-Scan images, and then use differential invariants on these lines to register together the 3D images with a high precision. The extraction of the crest lines is done by computing up to third order derivatives of the image intensity function with appropriate 3D filtering of the volumetric images, and by the 'marching lines' algorithm. The recovered lines are then approximated by splines curves, to compute at each point a number of differential invariants. Matching is finally performed by a new geometric hashing method. The whole chain is now completely automatic, and provides extremely robust and accurate results, even in the presence of severe occlusions. In this paper, we briefly describe the whole chain of processes, already presented to evaluate the accuracy of the approach on a couple of CT-scan images of a skull containing external markers.

  10. A method for the evaluation of thousands of automated 3D stem cell segmentations.

    Science.gov (United States)

    Bajcsy, P; Simon, M; Florczyk, S J; Simon, C G; Juba, D; Brady, M C

    2015-12-01

    There is no segmentation method that performs perfectly with any dataset in comparison to human segmentation. Evaluation procedures for segmentation algorithms become critical for their selection. The problems associated with segmentation performance evaluations and visual verification of segmentation results are exaggerated when dealing with thousands of three-dimensional (3D) image volumes because of the amount of computation and manual inputs needed. We address the problem of evaluating 3D segmentation performance when segmentation is applied to thousands of confocal microscopy images (z-stacks). Our approach is to incorporate experimental imaging and geometrical criteria, and map them into computationally efficient segmentation algorithms that can be applied to a very large number of z-stacks. This is an alternative approach to considering existing segmentation methods and evaluating most state-of-the-art algorithms. We designed a methodology for 3D segmentation performance characterization that consists of design, evaluation and verification steps. The characterization integrates manual inputs from projected surrogate 'ground truth' of statistically representative samples and from visual inspection into the evaluation. The novelty of the methodology lies in (1) designing candidate segmentation algorithms by mapping imaging and geometrical criteria into algorithmic steps, and constructing plausible segmentation algorithms with respect to the order of algorithmic steps and their parameters, (2) evaluating segmentation accuracy using samples drawn from probability distribution estimates of candidate segmentations and (3) minimizing human labour needed to create surrogate 'truth' by approximating z-stack segmentations with 2D contours from three orthogonal z-stack projections and by developing visual verification tools. We demonstrate the methodology by applying it to a dataset of 1253 mesenchymal stem cells. The cells reside on 10 different types of biomaterial

  11. Ice-Templated Assembly Strategy to Construct 3D Boron Nitride Nanosheet Networks in Polymer Composites for Thermal Conductivity Improvement.

    Science.gov (United States)

    Zeng, Xiaoliang; Yao, Yimin; Gong, Zhengyu; Wang, Fangfang; Sun, Rong; Xu, Jianbin; Wong, Ching-Ping

    2015-12-01

    Owing to the growing heat removal issue of modern electronic devices, polymer composites with high thermal conductivity have drawn much attention in the past few years. However, a traditional method to enhance the thermal conductivity of the polymers by addition of inorganic fillers usually creates composite with not only limited thermal conductivity but also other detrimental effects due to large amount of fillers required. Here, novel polymer composites are reported by first constructing 3D boron nitride nanosheets (3D-BNNS) network using ice-templated approach and then infiltrating them with epoxy matrix. The obtained polymer composites exhibit a high thermal conductivity (2.85 W m(-1) K(-1)), a low thermal expansion coefficient (24-32 ppm K(-1)), and an increased glass transition temperature (T(g)) at relatively low BNNSs loading (9.29 vol%). These results demonstrate that this approach opens a new avenue for design and preparation of polymer composites with high thermal conductivity. The polymer composites are potentially useful in advanced electronic packaging techniques, namely, thermal interface materials, underfill materials, molding compounds, and organic substrates.

  12. Ice-Templated Assembly Strategy to Construct 3D Boron Nitride Nanosheet Networks in Polymer Composites for Thermal Conductivity Improvement.

    Science.gov (United States)

    Zeng, Xiaoliang; Yao, Yimin; Gong, Zhengyu; Wang, Fangfang; Sun, Rong; Xu, Jianbin; Wong, Ching-Ping

    2015-12-01

    Owing to the growing heat removal issue of modern electronic devices, polymer composites with high thermal conductivity have drawn much attention in the past few years. However, a traditional method to enhance the thermal conductivity of the polymers by addition of inorganic fillers usually creates composite with not only limited thermal conductivity but also other detrimental effects due to large amount of fillers required. Here, novel polymer composites are reported by first constructing 3D boron nitride nanosheets (3D-BNNS) network using ice-templated approach and then infiltrating them with epoxy matrix. The obtained polymer composites exhibit a high thermal conductivity (2.85 W m(-1) K(-1)), a low thermal expansion coefficient (24-32 ppm K(-1)), and an increased glass transition temperature (T(g)) at relatively low BNNSs loading (9.29 vol%). These results demonstrate that this approach opens a new avenue for design and preparation of polymer composites with high thermal conductivity. The polymer composites are potentially useful in advanced electronic packaging techniques, namely, thermal interface materials, underfill materials, molding compounds, and organic substrates. PMID:26479262

  13. System-Level Thermal Modeling and Management for Multi-Core and 3D Microprocessors

    OpenAIRE

    Liu, Zao

    2014-01-01

    The continuously scaling down of CMOS technology inevitably increases the power density for high performance microprocessors, which makes thermal effects and related problems urgent and challenging. Unpredicted thermal behavior and on-chip thermal hot spots could lead to performance degradation of microprocessor chips, incurring reliability issues. Hence, it is becoming increasingly important to develop thermal modeling methods to predict the thermal behavior of microprocessor chips, and ther...

  14. Design and evaluation of a laboratory prototype system for 3D photoacoustic full breast tomography

    OpenAIRE

    Xia, W; Piras, D; Singh, M. K. A.; van Hespen, J. C. G.; Van Leeuwen, T. G.; Steenbergen, W Van; Manohar, S.

    2013-01-01

    Photoacoustic imaging can visualize vascularization-driven optical absorption contrast with great potential for breast cancer detection and diagnosis. State-of-the-art photoacoustic breast imaging systems are promising but are limited either by only a 2D imaging capability or by an insufficient imaging field-of-view (FOV). We present a laboratory prototype system designed for 3D photoacoustic full breast tomography, and comprehensively characterize it and evaluate its performance in imaging p...

  15. A 3D Osteoblast In Vitro Model for the Evaluation of Biomedical Materials

    OpenAIRE

    Luciana Restle; Daniela Costa-Silva; Emanuelle Stellet Lourenço; Rober Freitas Bachinski; Ana Carolina Batista; Adriana Brandão Ribeiro Linhares; Gutemberg Gomes Alves

    2015-01-01

    Biomedical materials for bone therapy are usually assessed for their biocompatibility and safety employing animal models or in vitro monolayer cell culture assays. However, alternative in vitro models may offer controlled conditions closer to physiological responses and reduce animal testing. In this work, we developed a 3D spheroidal cell culture with potential to evaluate simultaneously material-cell and cell-cell interactions. Different cell densities of murine MC3T3-E1 preosteoblasts or h...

  16. Investigation of seasonal thermal flow in a real dam reservoir using 3-D numerical modeling

    Directory of Open Access Journals (Sweden)

    Üneş Fatih

    2015-03-01

    Full Text Available Investigations indicate that correct estimation of seasonal thermal stratification in a dam reservoir is very important for the dam reservoir water quality modeling and water management problems. The main aim of this study is to develop a hydrodynamics model of an actual dam reservoir in three dimensions for simulating a real dam reservoir flows for different seasons. The model is developed using nonlinear and unsteady continuity, momentum, energy and k-ε turbulence model equations. In order to include the Coriolis force effect on the flow in a dam reservoir, Coriolis force parameter is also added the model equations. Those equations are constructed using actual dimensions, shape, boundary and initial conditions of the dam and reservoir. Temperature profiles and flow visualizations are used to evaluate flow conditions in the reservoir. Reservoir flow’s process and parameters are determined all over the reservoir. The mathematical model developed is capable of simulating the flow and thermal characteristics of the reservoir system for seasonal heat exchanges. Model simulations results obtained are compared with field measurements obtained from gauging stations for flows in different seasons. The results show a good agreement with the field measurements.

  17. Evaluation of an improved algorithm for producing realistic 3D breast software phantoms: Application for mammography

    Energy Technology Data Exchange (ETDEWEB)

    Bliznakova, K.; Suryanarayanan, S.; Karellas, A.; Pallikarakis, N. [Department of Medical Physics, School of Medicine, University of Patras, 26500 Rio-Patras (Greece); Department of Radiology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322 (United States); Department of Medical Physics, School of Medicine, University of Patras, 26500 Rio-Patras (Greece)

    2010-11-15

    Purpose: This work presents an improved algorithm for the generation of 3D breast software phantoms and its evaluation for mammography. Methods: The improved methodology has evolved from a previously presented 3D noncompressed breast modeling method used for the creation of breast models of different size, shape, and composition. The breast phantom is composed of breast surface, duct system and terminal ductal lobular units, Cooper's ligaments, lymphatic and blood vessel systems, pectoral muscle, skin, 3D mammographic background texture, and breast abnormalities. The key improvement is the development of a new algorithm for 3D mammographic texture generation. Simulated images of the enhanced 3D breast model without lesions were produced by simulating mammographic image acquisition and were evaluated subjectively and quantitatively. For evaluation purposes, a database with regions of interest taken from simulated and real mammograms was created. Four experienced radiologists participated in a visual subjective evaluation trial, as they judged the quality of the simulated mammograms, using the new algorithm compared to mammograms, obtained with the old modeling approach. In addition, extensive quantitative evaluation included power spectral analysis and calculation of fractal dimension, skewness, and kurtosis of simulated and real mammograms from the database. Results: The results from the subjective evaluation strongly suggest that the new methodology for mammographic breast texture creates improved breast models compared to the old approach. Calculated parameters on simulated images such as {beta} exponent deducted from the power law spectral analysis and fractal dimension are similar to those calculated on real mammograms. The results for the kurtosis and skewness are also in good coincidence with those calculated from clinical images. Comparison with similar calculations published in the literature showed good agreement in the majority of cases. Conclusions

  18. Uncertainty propagation in a 3-D thermal code for performance assessment of a nuclear waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Dutfoy, A. [Electricite de France (EDF), Research and Development Div., Safety and Reliability Branch, ESF, 92 - Clamart (France); Ritz, J.B. [Electricite de France (EDF), Research and Development Div., Fluid Mechanics and Heat Transfer, MFTT, 78 - Chatou (France)

    2001-07-01

    Given the very large time scale involved, the performance assessment of a nuclear waste repository requires numerical modelling. Because we are uncertain of the exact value of the input parameters, we have to analyse the impact of these uncertainties on the outcome of the physical models. The EDF Division Research and Development has set a reliability method to propagate these uncertainties or variability through models which requires much less physical simulations than the usual simulation methods. We apply the reliability method MEFISTO to a base case modelling the heat transfers in a virtual disposal in the future site of the French underground research laboratory, in the East of France. This study is led in collaboration with ANDRA which is the French Nuclear Waste Management Agency. With this exercise, we want to evaluate the thermal behaviour of a concept related to the variation of physical parameters and their uncertainty. (author)

  19. A comprehensive evaluation of the PRESAGE/optical-CT 3D dosimetry system

    Energy Technology Data Exchange (ETDEWEB)

    Sakhalkar, H. S.; Adamovics, J.; Ibbott, G.; Oldham, M. [Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710 (United States); Department of Chemistry and Biology, Rider University, Lawrenceville, New Jersey 08648 (United States); Department of Radiation Physics, M. D. Anderson Cancer Center, Houston, Texas 77030 (United States); Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710 (United States)

    2009-01-15

    This work presents extensive investigations to evaluate the robustness (intradosimeter consistency and temporal stability of response), reproducibility, precision, and accuracy of a relatively new 3D dosimetry system comprising a leuco-dye doped plastic 3D dosimeter (PRESAGE) and a commercial optical-CT scanner (OCTOPUS 5x scanner from MGS Research, Inc). Four identical PRESAGE 3D dosimeters were created such that they were compatible with the Radiologic Physics Center (RPC) head-and-neck (H and N) IMRT credentialing phantom. Each dosimeter was irradiated with a rotationally symmetric arrangement of nine identical small fields (1x3 cm{sup 2}) impinging on the flat circular face of the dosimeter. A repetitious sequence of three dose levels (4, 2.88, and 1.28 Gy) was delivered. The rotationally symmetric treatment resulted in a dose distribution with high spatial variation in axial planes but only gradual variation with depth along the long axis of the dosimeter. The significance of this treatment was that it facilitated accurate film dosimetry in the axial plane, for independent verification. Also, it enabled rigorous evaluation of robustness, reproducibility and accuracy of response, at the three dose levels. The OCTOPUS 5x commercial scanner was used for dose readout from the dosimeters at daily time intervals. The use of improved optics and acquisition technique yielded substantially improved noise characteristics (reduced to {approx}2%) than has been achieved previously. Intradosimeter uniformity of radiochromic response was evaluated by calculating a 3D gamma comparison between each dosimeter and axially rotated copies of the same dosimeter. This convenient technique exploits the rotational symmetry of the distribution. All points in the gamma comparison passed a 2% difference, 1 mm distance-to-agreement criteria indicating excellent intradosimeter uniformity even at low dose levels. Postirradiation, the dosimeters were all found to exhibit a slight increase in

  20. A magnetic resonance study of 3d transition metals and thermal donors in silicon

    International Nuclear Information System (INIS)

    This thesis describes a study of 3d-transition metal impurities in silicon (titanium and iron in particular) and a study of oxygen-related heat-treatment centers in silicon, both carried out mainly by magnetic resonances techniques like EPR and ENDOR. 119 refs.; 31 figs.; 14 tabs

  1. Role of 3D-CT for orthodontic and ENT evaluation in Goldenhar syndrome.

    Science.gov (United States)

    Saccomanno, S; Greco, F; D'Alatri, L; De Corso, E; Pandolfini, M; Sergi, B; Pirronti, T; Deli, R

    2014-08-01

    Goldenhar syndrome is a congenital condition that includes anomalies of the derivatives of the first and second brachial arches, vertebral defects and ocular abnormalities. It is also known as oculo-auriculo-vertebrale syndrome (OAVS), hemifacial microsomia, or first or second brachial arch syndrome. It was first described by Van Duyse in 1882 and better studied by M. Goldenhar in 1952. Its treatment requires a multidisciplinary approach. Herein, we describe the value of 3D-CT evaluation in a patient with Goldenhar syndrome, with particular regard to planning diagnostic and therapeutic approach. A 7-year-old boy with Goldenhar syndrome with definite post-natal genetic diagnosis was referred to our Department of Radiology for neuroimaging of the temporal bone. By 3D-CT evaluation of this young patient we observed the asymmetry of the condyles with the right one dysmorphic, short and wide; the auricle of the right ear was replaced by a dysmorphic rough; the right middle ear had a hypoplastic tympanic cavity and the internal auditory canal of right ear was atresic. In our experience, 3D-CT is a powerful diagnostic instrument and offers many advantages: volumetric reproduction of cranium and soft tissues, no overlap of anatomic parts that limits the visibility of various structures, high precision and assurance of images, and a constant and easily reproducible reference system. In our case, 3D-CT offered a very complete evaluation of all malformations of mandibular and temporal bone that characterize this syndrome and representing an important step for ENT and orthodontic therapeutic approaches.

  2. Two-dimensional evaluation of 3D needled Cf/SiC composite fiber bundle surface

    Science.gov (United States)

    Wei, Jinhua; Lin, Bin; Cao, Xiaoyan; Zhang, Xiaofeng; Fang, Sheng

    2015-11-01

    The variations of fiber bundle surface microstructure have direct influence on the material performance, especially the friction and wear properties. Therefore, fiber bundle is the smallest evaluation unit of Cf/SiC composite surface. However, due to the anisotropy and inhomogeneity of Cf/SiC composite, it is difficult to evaluate the surface characteristics. Researchers think that two-dimensional evaluation is not suitable for the composites surface assessment any more because of its complex composition and varied surface structure. In this paper, a novel method is introduced for the evaluation of 3D needled Cf/SiC composite fiber bundle surface. On the level of Cf/SiC composite fiber bundle surface, two-dimensional evaluation method is adopted, with which the fiber bundle surface quality can be quantitatively evaluated by the two-dimensional surface roughness Ra. As long as the extracted surface profiles averagely distributed on Cf/SiC composite fiber bundle surface, with appropriate sampling length and sampling number, the mean value of Ra can estimate the whole surface roughness, thus reflecting the roughness degree of surface accurately. This study not only benefits the detection of 3D needled Cf/SiC composite fiber bundle surface quality, and lays a foundation on the evaluation of material functional features in further. And it corresponds to the convenient application in engineering practice.

  3. Error Evaluation in a Stereovision-Based 3D Reconstruction System

    Directory of Open Access Journals (Sweden)

    Kohler Sophie

    2010-01-01

    Full Text Available The work presented in this paper deals with the performance analysis of the whole 3D reconstruction process of imaged objects, specifically of the set of geometric primitives describing their outline and extracted from a pair of images knowing their associated camera models. The proposed analysis focuses on error estimation for the edge detection process, the starting step for the whole reconstruction procedure. The fitting parameters describing the geometric features composing the workpiece to be evaluated are used as quality measures to determine error bounds and finally to estimate the edge detection errors. These error estimates are then propagated up to the final 3D reconstruction step. The suggested error analysis procedure for stereovision-based reconstruction tasks further allows evaluating the quality of the 3D reconstruction. The resulting final error estimates enable lastly to state if the reconstruction results fulfill a priori defined criteria, for example, fulfill dimensional constraints including tolerance information, for vision-based quality control applications for example.

  4. Automotive Underhood Thermal Management Analysis Using 3-D Coupled Thermal-Hydrodynamic Computer Models: Thermal Radiation Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Pannala, S; D' Azevedo, E; Zacharia, T

    2002-02-26

    The goal of the radiation modeling effort was to develop and implement a radiation algorithm that is fast and accurate for the underhood environment. As part of this CRADA, a net-radiation model was chosen to simulate radiative heat transfer in an underhood of a car. The assumptions (diffuse-gray and uniform radiative properties in each element) reduce the problem tremendously and all the view factors for radiation thermal calculations can be calculated once and for all at the beginning of the simulation. The cost for online integration of heat exchanges due to radiation is found to be less than 15% of the baseline CHAD code and thus very manageable. The off-line view factor calculation is constructed to be very modular and has been completely integrated to read CHAD grid files and the output from this code can be read into the latest version of CHAD. Further integration has to be performed to accomplish the same with STAR-CD. The main outcome of this effort is to obtain a highly scalable and portable simulation capability to model view factors for underhood environment (for e.g. a view factor calculation which took 14 hours on a single processor only took 14 minutes on 64 processors). The code has also been validated using a simple test case where analytical solutions are available. This simulation capability gives underhood designers in the automotive companies the ability to account for thermal radiation - which usually is critical in the underhood environment and also turns out to be one of the most computationally expensive components of underhood simulations. This report starts off with the original work plan as elucidated in the proposal in section B. This is followed by Technical work plan to accomplish the goals of the project in section C. In section D, background to the current work is provided with references to the previous efforts this project leverages on. The results are discussed in section 1E. This report ends with conclusions and future scope of

  5. Evaluation of Large Intracranial Aneurysms with Cine MRA and 3D Contrast-Enhanced MRA

    Institute of Scientific and Technical Information of China (English)

    朱文珍; 冯定义; 漆剑频; 夏黎明; 王承缘

    2004-01-01

    Summary: The value of combined application of both ECG-gated cine MRA and 3D-CEMRA in the detection of large intracranial aneurysms was evaluated and the findings were compared with those of conventional MRA and DSA. Twenty-four patients with 26 large intraeranial aneurysms underwent MRI and DSA. All these aneurysms, diameter from 15 to 39 mm, were located at internal cerebral artery (n = 12), vertebral artery (n = 3), basilar artery (n = 4), anterior cerebral artery (n =2), middle cerebral artery (n=2), anterior communicate artery (n=2) and posterior communicate artery (n= 1). Thirteen cases of hematoma or cavernoma were studied as control group. All patients were examined on GE 1.5T MR system. ECG-gated eine MRA was performed with 2D multi-phase fast gradient-recalled echo sequence in a single section. All the images were analyzed with signal intensity VS time curve for differentiating intraaneurysmal blood flow from static tissue.The results were analzsed by statistic "t" test. 3D-CEMRA was performed with spoiled gradient-recalled echo and one dose of Gd-DTPA. All data was processed with multi-plannar reformat (MPR)and tomography for the demonstration of aneurysms in detail. All 26 aneurysms were demonstrated successfully by combined application of both cine MRA and 3D-CEMRA. Compared to DSA and conventional 3D-MOTSA, its sensitivity and specificity figures were both 100 %. Cine MRA could differentiate the blood flow from the static tissue. The intensity VS time curves of intraaneurysmal blood flow offered fluctuating form and average signal change between systole and diastole period was about 89.8±37.4; However, under the control group, intraaneurysmal thrombus or cerebral hemorrhage or eavernomas had no significant signal change and the curves offered steady form with the average signal change being about 8.2 ± 6. 3. There was statistically significant difference between the intraaneurysmal blood flow and static tissue (P= 0. 025, <0.05). 3D-CEMRA was very

  6. On the Efficiency of Image Metrics for Evaluating the Visual Quality of 3D Models.

    Science.gov (United States)

    Lavoue, Guillaume; Larabi, Mohamed Chaker; Vasa, Libor

    2016-08-01

    3D meshes are deployed in a wide range of application processes (e.g., transmission, compression, simplification, watermarking and so on) which inevitably introduce geometric distortions that may alter the visual quality of the rendered data. Hence, efficient model-based perceptual metrics, operating on the geometry of the meshes being compared, have been recently introduced to control and predict these visual artifacts. However, since the 3D models are ultimately visualized on 2D screens, it seems legitimate to use images of the models (i.e., snapshots from different viewpoints) to evaluate their visual fidelity. In this work we investigate the use of image metrics to assess the visual quality of 3D models. For this goal, we conduct a wide-ranging study involving several 2D metrics, rendering algorithms, lighting conditions and pooling algorithms, as well as several mean opinion score databases. The collected data allow (1) to determine the best set of parameters to use for this image-based quality assessment approach and (2) to compare this approach to the best performing model-based metrics and determine for which use-case they are respectively adapted. We conclude by exploring several applications that illustrate the benefits of image-based quality assessment. PMID:26394428

  7. Heavy Ion Induced SEU Sensitivity Evaluation of 3D Integrated SRAMs

    CERN Document Server

    Cao, Xuebing; Huo, Mingxue; Wang, Tianqi; Li, Anlong; Qi, Chunhua; Wang, Jinxiang

    2016-01-01

    Heavy ions induced single event upset (SEU) sensitivity of three-dimensional integrated SRAMs are evaluated by using Monte Carlo sumulation methods based on Geant4. The cross sections of SEUs and Multi Cell Upsets (MCUs) for 3D SRAM are simulated by using heavy ions with different energies and LETs. The results show that the sensitivity of different die of 3D SRAM has obvious discrepancies at low LET. Average percentage of MCUs of 3D SRAMs rises from 17.2% to 32.95% when LET increases from 42.19 MeV cm2/mg to 58.57MeV cm2/mg. As for a certain LET, the percentage of MCUs shows a notable distinction between face-to-face structure and back-to-face structure. For back-to-face structure, the percentage of MCUs increases with the deeper die. However, the face-to-face die presents the relatively low percentage of MCUs. The comparison of SEU cross sections for planar SRAMs and experiment data are conducted to indicate the effectiveness of our simulation method. Finally, we compare the upset cross sections of planar p...

  8. Numerical Analysis of Thermal Remediation in 3D Field-Scale Fractured Geologic Media.

    Science.gov (United States)

    Chen, Fei; Falta, Ronald W; Murdoch, Lawrence C

    2015-01-01

    Thermal methods are promising for remediating fractured geologic media contaminated with volatile organic compounds, and the success of this process depends on the coupled heat transfer, multiphase flow, and thermodynamics. This study analyzed field-scale removal of trichloroethylene (TCE) and heat transfer behavior in boiling fractured geologic media using the multiple interacting continua method. This method can resolve local gradients in the matrix and is less computationally demanding than alternative methods like discrete fracture-matrix models. A 2D axisymmetric model was used to simulate a single element of symmetry in a repeated pattern of extraction wells inside a large heated zone and evaluate effects of parameter sensitivity on contaminant recovery. The results showed that the removal of TCE increased with matrix permeability, and the removal rate was more sensitive to matrix permeability than any other parameter. Increasing fracture density promoted TCE removal, especially when the matrix permeability was low (e.g., simulate an entire treatment zone and the surrounding groundwater in fractured material, with the interaction between them being considered. Boiling was initiated in the center of the upper part of the heated region and expanded toward the boundaries. This boiling process resulted in a large increase in the TCE removal rate and spread of TCE to the vadose zone and the peripheries of the heated zone. The incorporation of extraction wells helped control the contaminant from migrating to far regions. After 22 d, more than 99.3% of TCE mass was recovered in the simulation. PMID:25040727

  9. Mining 3D Patterns from Gene Expression Temporal Data: A New Tricluster Evaluation Measure

    Directory of Open Access Journals (Sweden)

    David Gutiérrez-Avilés

    2014-01-01

    Full Text Available Microarrays have revolutionized biotechnological research. The analysis of new data generated represents a computational challenge due to the characteristics of these data. Clustering techniques are applied to create groups of genes that exhibit a similar behavior. Biclustering emerges as a valuable tool for microarray data analysis since it relaxes the constraints for grouping, allowing genes to be evaluated only under a subset of the conditions. However, if a third dimension appears in the data, triclustering is the appropriate tool for the analysis. This occurs in longitudinal experiments in which the genes are evaluated under conditions at several time points. All clustering, biclustering, and triclustering techniques guide their search for solutions by a measure that evaluates the quality of clusters. We present an evaluation measure for triclusters called Mean Square Residue 3D. This measure is based on the classic biclustering measure Mean Square Residue. Mean Square Residue 3D has been applied to both synthetic and real data and it has proved to be capable of extracting groups of genes with homogeneous patterns in subsets of conditions and times, and these groups have shown a high correlation level and they are also related to their functional annotations extracted from the Gene Ontology project.

  10. Mining 3D patterns from gene expression temporal data: a new tricluster evaluation measure.

    Science.gov (United States)

    Gutiérrez-Avilés, David; Rubio-Escudero, Cristina

    2014-01-01

    Microarrays have revolutionized biotechnological research. The analysis of new data generated represents a computational challenge due to the characteristics of these data. Clustering techniques are applied to create groups of genes that exhibit a similar behavior. Biclustering emerges as a valuable tool for microarray data analysis since it relaxes the constraints for grouping, allowing genes to be evaluated only under a subset of the conditions. However, if a third dimension appears in the data, triclustering is the appropriate tool for the analysis. This occurs in longitudinal experiments in which the genes are evaluated under conditions at several time points. All clustering, biclustering, and triclustering techniques guide their search for solutions by a measure that evaluates the quality of clusters. We present an evaluation measure for triclusters called Mean Square Residue 3D. This measure is based on the classic biclustering measure Mean Square Residue. Mean Square Residue 3D has been applied to both synthetic and real data and it has proved to be capable of extracting groups of genes with homogeneous patterns in subsets of conditions and times, and these groups have shown a high correlation level and they are also related to their functional annotations extracted from the Gene Ontology project. PMID:25143987

  11. Investigation and evaluation of pointing modalities for interactive stereoscopic 3D TV

    OpenAIRE

    Haiyue Yuan,; Calic, J.; Fernando, A.; Kondoz, A

    2013-01-01

    The recent proliferation of stereoscopic three dimensional (3D) video technology has fostered a large body of research into 3D video capture, production, compression and delivery. However, little research has been dedicated to the design practices of stereoscopic 3D video interaction. Interaction tasks such as pointing and selection are critical to the consumer's experience of the 3D video technology. This paper presents investigation of pointing modalities in the context of stereoscopic 3D t...

  12. Evaluation of absolute phase for 3D profile measurement using fringe projection

    Institute of Scientific and Technical Information of China (English)

    Mengtao Huang; Zhuangde Jiang; Bing Li; Suping Fang

    2006-01-01

    A new method of absolute phase evaluation for three-dimensional (3D) profile measurement using fringe projection is presented, which combines the gray code and the phase shift technique. Two kinds of fringe patterns are projected onto the object surface respectively, one is sinusoidal intensity distribution used for phase demodulation and the other is gray code fringe pattern for unwrapping. These images are acquired by camera and stored into computer. The absolute phase is obtained by analyzing these images. The validity of this method is verified experimentally. The method is superior to other phase unwrapping methods.

  13. A preliminary evaluation work on a 3D ultrasound imaging system for 2D array transducer

    Science.gov (United States)

    Zhong, Xiaoli; Li, Xu; Yang, Jiali; Li, Chunyu; Song, Junjie; Ding, Mingyue; Yuchi, Ming

    2016-04-01

    This paper presents a preliminary evaluation work on a pre-designed 3-D ultrasound imaging system. The system mainly consists of four parts, a 7.5MHz, 24×24 2-D array transducer, the transmit/receive circuit, power supply, data acquisition and real-time imaging module. The row-column addressing scheme is adopted for the transducer fabrication, which greatly reduces the number of active channels . The element area of the transducer is 4.6mm by 4.6mm. Four kinds of tests were carried out to evaluate the imaging performance, including the penetration depth range, axial and lateral resolution, positioning accuracy and 3-D imaging frame rate. Several strong reflection metal objects , fixed in a water tank, were selected for the purpose of imaging due to a low signal-to-noise ratio of the transducer. The distance between the transducer and the tested objects , the thickness of aluminum, and the seam width of the aluminum sheet were measured by a calibrated micrometer to evaluate the penetration depth, the axial and lateral resolution, respectively. The experiment al results showed that the imaging penetration depth range was from 1.0cm to 6.2cm, the axial and lateral resolution were 0.32mm and 1.37mm respectively, the imaging speed was up to 27 frames per second and the positioning accuracy was 9.2%.

  14. Evaluation of PC-ISO for customized, 3D Printed, gynecologic 192-Ir HDR brachytherapy applicators.

    Science.gov (United States)

    Cunha, J Adam M; Mellis, Katherine; Sethi, Rajni; Siauw, Timmy; Sudhyadhom, Atchar; Garg, Animesh; Goldberg, Ken; Hsu, I-Chow; Pouliot, Jean

    2015-01-01

    The purpose of this study was to evaluate the radiation attenuation properties of PC-ISO, a commercially available, biocompatible, sterilizable 3D printing material, and its suitability for customized, single-use gynecologic (GYN) brachytherapy applicators that have the potential for accurate guiding of seeds through linear and curved internal channels. A custom radiochromic film dosimetry apparatus was 3D-printed in PC-ISO with a single catheter channel and a slit to hold a film segment. The apparatus was designed specifically to test geometry pertinent for use of this material in a clinical setting. A brachytherapy dose plan was computed to deliver a cylindrical dose distribution to the film. The dose plan used an 192Ir source and was normalized to 1500 cGy at 1 cm from the channel. The material was evaluated by comparing the film exposure to an identical test done in water. The Hounsfield unit (HU) distributions were computed from a CT scan of the apparatus and compared to the HU distribution of water and the HU distribution of a commercial GYN cylinder applicator. The dose depth curve of PC-ISO as measured by the radiochromic film was within 1% of water between 1 cm and 6 cm from the channel. The mean HU was -10 for PC-ISO and -1 for water. As expected, the honeycombed structure of the PC-ISO 3D printing process created a moderate spread of HU values, but the mean was comparable to water. PC-ISO is sufficiently water-equivalent to be compatible with our HDR brachytherapy planning system and clinical workflow and, therefore, it is suitable for creating custom GYN brachytherapy applicators. Our current clinical practice includes the use of custom GYN applicators made of commercially available PC-ISO when doing so can improve the patient's treatment.  PMID:25679174

  15. Development and Evaluation of High-Performance Decorrelation Algorithms for the Nonalternating 3D Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Quiles FJ

    2007-01-01

    Full Text Available We introduce and evaluate the implementations of three parallel video-sequences decorrelation algorithms. The proposed algorithms are based on the nonalternating classic three-dimensional wavelet transform (3D-WT. The parallel implementations of the algorithms are developed and tested on a shared memory system, an SGI origin 3800 supercomputer making use of a message-passing paradigm. We evaluate and analyze the performance of the implementations in terms of the response time and speed-up factor by varying the number of processors and various video coding parameters. The key points enabling the development of highly efficient implementations rely on the partitioning of the video sequences into groups of frames and a workload distribution strategy supplemented by the use of parallel I/O primitives, for better exploiting the inherent features of the application and computing platform. We also evaluate the effectiveness of our algorithms in terms of the first-order entropy.

  16. 3D COMSOL Simulations for Thermal Deflection of HFIR Fuel Plate in the "Cheverton-Kelley" Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Jain, Prashant K [ORNL; Freels, James D [ORNL; Cook, David Howard [ORNL

    2012-08-01

    Three dimensional simulation capabilities are currently being developed at Oak Ridge National Laboratory using COMSOL Multiphysics, a finite element modeling software, to investigate thermal expansion of High Flux Isotope Reactor (HFIR) s low enriched uranium fuel plates. To validate simulations, 3D models have also been developed for the experimental setup used by Cheverton and Kelley in 1968 to investigate the buckling and thermal deflections of HFIR s highly enriched uranium fuel plates. Results for several simulations are presented in this report, and comparisons with the experimental data are provided when data are available. A close agreement between the simulation results and experimental findings demonstrates that the COMSOL simulations are able to capture the thermal expansion physics accurately and that COMSOL could be deployed as a predictive tool for more advanced computations at realistic HFIR conditions to study temperature-induced fuel plate deflection behavior.

  17. THE PERFORMANCE EVALUATION OF MULTI-IMAGE 3D RECONSTRUCTION SOFTWARE WITH DIFFERENT SENSORS

    Directory of Open Access Journals (Sweden)

    V. Mousavi

    2015-12-01

    Full Text Available Today, multi-image 3D reconstruction is an active research field and generating three dimensional model of the objects is one the most discussed issues in Photogrammetry and Computer Vision that can be accomplished using range-based or image-based methods. Very accurate and dense point clouds generated by range-based methods such as structured light systems and laser scanners has introduced them as reliable tools in the industry. Image-based 3D digitization methodologies offer the option of reconstructing an object by a set of unordered images that depict it from different viewpoints. As their hardware requirements are narrowed down to a digital camera and a computer system, they compose an attractive 3D digitization approach, consequently, although range-based methods are generally very accurate, image-based methods are low-cost and can be easily used by non-professional users. One of the factors affecting the accuracy of the obtained model in image-based methods is the software and algorithm used to generate three dimensional model. These algorithms are provided in the form of commercial software, open source and web-based services. Another important factor in the accuracy of the obtained model is the type of sensor used. Due to availability of mobile sensors to the public, popularity of professional sensors and the advent of stereo sensors, a comparison of these three sensors plays an effective role in evaluating and finding the optimized method to generate three-dimensional models. Lots of research has been accomplished to identify a suitable software and algorithm to achieve an accurate and complete model, however little attention is paid to the type of sensors used and its effects on the quality of the final model. The purpose of this paper is deliberation and the introduction of an appropriate combination of a sensor and software to provide a complete model with the highest accuracy. To do this, different software, used in previous

  18. The Performance Evaluation of Multi-Image 3d Reconstruction Software with Different Sensors

    Science.gov (United States)

    Mousavi, V.; Khosravi, M.; Ahmadi, M.; Noori, N.; Naveh, A. Hosseini; Varshosaz, M.

    2015-12-01

    Today, multi-image 3D reconstruction is an active research field and generating three dimensional model of the objects is one the most discussed issues in Photogrammetry and Computer Vision that can be accomplished using range-based or image-based methods. Very accurate and dense point clouds generated by range-based methods such as structured light systems and laser scanners has introduced them as reliable tools in the industry. Image-based 3D digitization methodologies offer the option of reconstructing an object by a set of unordered images that depict it from different viewpoints. As their hardware requirements are narrowed down to a digital camera and a computer system, they compose an attractive 3D digitization approach, consequently, although range-based methods are generally very accurate, image-based methods are low-cost and can be easily used by non-professional users. One of the factors affecting the accuracy of the obtained model in image-based methods is the software and algorithm used to generate three dimensional model. These algorithms are provided in the form of commercial software, open source and web-based services. Another important factor in the accuracy of the obtained model is the type of sensor used. Due to availability of mobile sensors to the public, popularity of professional sensors and the advent of stereo sensors, a comparison of these three sensors plays an effective role in evaluating and finding the optimized method to generate three-dimensional models. Lots of research has been accomplished to identify a suitable software and algorithm to achieve an accurate and complete model, however little attention is paid to the type of sensors used and its effects on the quality of the final model. The purpose of this paper is deliberation and the introduction of an appropriate combination of a sensor and software to provide a complete model with the highest accuracy. To do this, different software, used in previous studies, were compared and

  19. Neutronic and thermal-hydraulic coupling for 3D reactor core modeling combining MCB and fluent

    Directory of Open Access Journals (Sweden)

    Królikowski Igor P.

    2015-09-01

    Full Text Available Three-dimensional simulations of neutronics and thermal hydraulics of nuclear reactors are a tool used to design nuclear reactors. The coupling of MCB and FLUENT is presented, MCB allows to simulate neutronics, whereas FLUENT is computational fluid dynamics (CFD code. The main purpose of the coupling is to exchange data such as temperature and power profile between both codes. Temperature required as an input parameter for neutronics is significant since cross sections of nuclear reactions depend on temperature. Temperature may be calculated in thermal hydraulics, but this analysis needs as an input the power profile, which is a result from neutronic simulations. Exchange of data between both analyses is required to solve this problem. The coupling is a better solution compared to the assumption of estimated values of the temperatures or the power profiles; therefore the coupled analysis was created. This analysis includes single transient neutronic simulation and several steady-state thermal simulations. The power profile is generated in defined points in time during the neutronic simulation for the thermal analysis to calculate temperature. The coupled simulation gives information about thermal behavior of the reactor, nuclear reactions in the core, and the fuel evolution in time. Results show that there is strong influence of neutronics on thermal hydraulics. This impact is stronger than the impact of thermal hydraulics on neutronics. Influence of the coupling on temperature and neutron multiplication factor is presented. The analysis has been performed for the ELECTRA reactor, which is lead-cooled fast reactor concept, where the coolant fl ow is generated only by natural convection

  20. Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model.

    Science.gov (United States)

    Simão, D; Pinto, C; Fernandes, P; Peddie, C J; Piersanti, S; Collinson, L M; Salinas, S; Saggio, I; Schiavo, G; Kremer, E J; Brito, C; Alves, P M

    2016-01-01

    Gene therapy is a promising approach with enormous potential for treatment of neurodegenerative disorders. Viral vectors derived from canine adenovirus type 2 (CAV-2) present attractive features for gene delivery strategies in the human brain, by preferentially transducing neurons, are capable of efficient axonal transport to afferent brain structures, have a 30-kb cloning capacity and have low innate and induced immunogenicity in preclinical tests. For clinical translation, in-depth preclinical evaluation of efficacy and safety in a human setting is primordial. Stem cell-derived human neural cells have a great potential as complementary tools by bridging the gap between animal models, which often diverge considerably from human phenotype, and clinical trials. Herein, we explore helper-dependent CAV-2 (hd-CAV-2) efficacy and safety for gene delivery in a human stem cell-derived 3D neural in vitro model. Assessment of hd-CAV-2 vector efficacy was performed at different multiplicities of infection, by evaluating transgene expression and impact on cell viability, ultrastructural cellular organization and neuronal gene expression. Under optimized conditions, hd-CAV-2 transduction led to stable long-term transgene expression with minimal toxicity. hd-CAV-2 preferentially transduced neurons, whereas human adenovirus type 5 (HAdV5) showed increased tropism toward glial cells. This work demonstrates, in a physiologically relevant 3D model, that hd-CAV-2 vectors are efficient tools for gene delivery to human neurons, with stable long-term transgene expression and minimal cytotoxicity.

  1. MAL Daylight Photodynamic Therapy for Actinic Keratosis: Clinical and Imaging Evaluation by 3D Camera

    Directory of Open Access Journals (Sweden)

    Carmen Cantisani

    2016-07-01

    Full Text Available Non-melanoma skin cancer is the most common skin cancer with an incidence that varies widely worldwide. Among them, actinic keratosis (AK, considered by some authors as in situ squamous cell carcinoma (SCC, are the most common and reflect an abnormal multistep skin cell development due to the chronic ultraviolet (UV light exposure. No ideal treatment exists, but the potential risk of their development in a more invasive form requires prompt treatment. As patients usually present with multiple AK on fields of actinic damage, there is a need for effective, safe, simple and short treatments which allow the treatment of large areas. To achieve this, daylight photodynamic therapy (DL-PDT is an innovative treatment for multiple mild actinic keratosis, well tolerated by patients. Patients allocated to the PDT unit, affected by multiple mild−moderate and severe actinic keratosis on sun-exposed areas treated with DL-PDT, were clinically evaluated at baseline and every three months with an Antera 3D, Miravex© camera. Clinical and 3D images were performed at each clinical check almost every three months. In this retrospective study, 331 patients (56.7% male, 43.3% female were treated with DL-PDT. We observed a full clearance in more than two-thirds of patients with one or two treatments. Different responses depend on the number of lesions and on their severity; for patients with 1–3 lesions and with grade I or II AK, a full clearance was reached in 85% of cases with a maximum of two treatments. DL-PDT in general improved skin tone and erased sun damage. Evaluating each Antera 3D images, hemoglobin concentration and pigmentation, a skin color and tone improvement in 310 patients was observed. DL-PDT appears as a promising, effective, simple, tolerable and practical treatment for actinic damage associated with AK, and even treatment of large areas can be with little or no pain. The 3D imaging allowed for quantifying in real time the aesthetic benefits

  2. MAL Daylight Photodynamic Therapy for Actinic Keratosis: Clinical and Imaging Evaluation by 3D Camera.

    Science.gov (United States)

    Cantisani, Carmen; Paolino, Giovanni; Pellacani, Giovanni; Didona, Dario; Scarno, Marco; Faina, Valentina; Gobello, Tommaso; Calvieri, Stefano

    2016-07-11

    Non-melanoma skin cancer is the most common skin cancer with an incidence that varies widely worldwide. Among them, actinic keratosis (AK), considered by some authors as in situ squamous cell carcinoma (SCC), are the most common and reflect an abnormal multistep skin cell development due to the chronic ultraviolet (UV) light exposure. No ideal treatment exists, but the potential risk of their development in a more invasive form requires prompt treatment. As patients usually present with multiple AK on fields of actinic damage, there is a need for effective, safe, simple and short treatments which allow the treatment of large areas. To achieve this, daylight photodynamic therapy (DL-PDT) is an innovative treatment for multiple mild actinic keratosis, well tolerated by patients. Patients allocated to the PDT unit, affected by multiple mild-moderate and severe actinic keratosis on sun-exposed areas treated with DL-PDT, were clinically evaluated at baseline and every three months with an Antera 3D, Miravex(©) camera. Clinical and 3D images were performed at each clinical check almost every three months. In this retrospective study, 331 patients (56.7% male, 43.3% female) were treated with DL-PDT. We observed a full clearance in more than two-thirds of patients with one or two treatments. Different responses depend on the number of lesions and on their severity; for patients with 1-3 lesions and with grade I or II AK, a full clearance was reached in 85% of cases with a maximum of two treatments. DL-PDT in general improved skin tone and erased sun damage. Evaluating each Antera 3D images, hemoglobin concentration and pigmentation, a skin color and tone improvement in 310 patients was observed. DL-PDT appears as a promising, effective, simple, tolerable and practical treatment for actinic damage associated with AK, and even treatment of large areas can be with little or no pain. The 3D imaging allowed for quantifying in real time the aesthetic benefits of DL

  3. Two-photon luminescence thermometry: towards 3D high-resolution thermal imaging of waveguides.

    Science.gov (United States)

    He, Ruiyun; Vázquez de Aldana, Javier Rodríguez; Pedrola, Ginés Lifante; Chen, Feng; Jaque, Daniel

    2016-07-11

    We report on the use of the Erbium-based luminescence thermometry to realize high resolution, three dimensional thermal imaging of optical waveguides. Proof of concept is demonstrated in a 980-nm laser pumped ultrafast laser inscribed waveguide in Er:Yb phosphate glass. Multi-photon microscopy images revealed the existence of well confined intra-waveguide temperature increments as large as 200 °C for moderate 980-nm pump powers of 120 mW. Numerical simulations and experimental data reveal that thermal loading can be substantially reduced if pump events are separated more than the characteristic thermal time that for the waveguides investigated is in the ms time scale. PMID:27410882

  4. Fatigue crack growth simulations of 3-D linear elastic cracks under thermal load by XFEM

    Institute of Scientific and Technical Information of China (English)

    Himanshu PATHAK[1; Akhilendra SINGH[2; I.V. SINGH[3; S. K. YADAV[3

    2015-01-01

    This paper deals with the fatigue crack growth simulations of three-dimensional linear elastic cracks by XFEM under cyclic thermal load. Both temperature and displacement approximations are extrinsically enriched by Heaviside and crack front enrichment functions. Crack growth is modelled by successive linear extensions, and the end points of these linear extensions are joined by cubic spline segments to obtain a modified crack front. Different crack geometries such as planer, non-planer and arbitrary spline shape cracks are simulated under thermal shock, adiabatic and isothermal loads to reveal the sturdiness and versatility of the XFEM approach.

  5. Design and Performance Evaluation on Ultra-Wideband Time-Of-Arrival 3D Tracking System

    Science.gov (United States)

    Ni, Jianjun; Arndt, Dickey; Ngo, Phong; Dusl, John

    2012-01-01

    A three-dimensional (3D) Ultra-Wideband (UWB) Time--of-Arrival (TOA) tracking system has been studied at NASA Johnson Space Center (JSC) to provide the tracking capability inside the International Space Station (ISS) modules for various applications. One of applications is to locate and report the location where crew experienced possible high level of carbon-dioxide and felt upset. In order to accurately locate those places in a multipath intensive environment like ISS modules, it requires a robust real-time location system (RTLS) which can provide the required accuracy and update rate. A 3D UWB TOA tracking system with two-way ranging has been proposed and studied. The designed system will be tested in the Wireless Habitat Testbed which simulates the ISS module environment. In this presentation, we discuss the 3D TOA tracking algorithm and the performance evaluation based on different tracking baseline configurations. The simulation results show that two configurations of the tracking baseline are feasible. With 100 picoseconds standard deviation (STD) of TOA estimates, the average tracking error 0.2392 feet (about 7 centimeters) can be achieved for configuration Twisted Rectangle while the average tracking error 0.9183 feet (about 28 centimeters) can be achieved for configuration Slightly-Twisted Top Rectangle . The tracking accuracy can be further improved with the improvement of the STD of TOA estimates. With 10 picoseconds STD of TOA estimates, the average tracking error 0.0239 feet (less than 1 centimeter) can be achieved for configuration "Twisted Rectangle".

  6. Development of NSSS Thermal-Hydraulic Model for KNPEC-2 Simulator Using the Best-Estimate Code RETRAN-3D

    International Nuclear Information System (INIS)

    The Nuclear Steam Supply System (NSSS) thermal-hydraulic model adopted in the Korea Nuclear Plant Education Center (KNPEC)-2 simulator was provided in the early 1980s. The reference plant for KNPEC-2 is the Yong Gwang Nuclear Unit 1, which is a Westinghouse-type 3-loop, 950 MW(electric) pressurized water reactor. Because of the limited computational capability at that time, it uses overly simplified physical models and assumptions for a real-time simulation of NSSS thermal-hydraulic transients. This may entail inaccurate results and thus, the possibility of so-called ''negative training,'' especially for complicated two-phase flows in the reactor coolant system. To resolve the problem, we developed a realistic NSSS thermal-hydraulic program (named ARTS code) based on the best-estimate code RETRAN-3D. The systematic assessment of ARTS has been conducted by both a stand-alone test and an integrated test in the simulator environment. The non-integrated stand-alone test (NIST) results were reasonable in terms of accuracy, real-time simulation capability, and robustness. After successful completion of the NIST, ARTS was integrated with a 3-D reactor kinetics model and other system models. The site acceptance test (SAT) has been completed successively and confirmed to comply with the ANSI/ANS-3.5-1998 simulator software performance criteria. This paper presents our efforts for the ARTS development and some test results of the NIST and SAT

  7. Thermal Resistance across Interfaces Comprising Dimensionally Mismatched Carbon Nanotube-Graphene Junctions in 3D Carbon Nanomaterials

    Directory of Open Access Journals (Sweden)

    Jungkyu Park

    2014-01-01

    Full Text Available In the present study, reverse nonequilibrium molecular dynamics is employed to study thermal resistance across interfaces comprising dimensionally mismatched junctions of single layer graphene floors with (6,6 single-walled carbon nanotube (SWCNT pillars in 3D carbon nanomaterials. Results obtained from unit cell analysis indicate the presence of notable interfacial thermal resistance in the out-of-plane direction (along the longitudinal axis of the SWCNTs but negligible resistance in the in-plane direction along the graphene floor. The interfacial thermal resistance in the out-of-plane direction is understood to be due to the change in dimensionality as well as phonon spectra mismatch as the phonons propagate from SWCNTs to the graphene sheet and then back again to the SWCNTs. The thermal conductivity of the unit cells was observed to increase nearly linearly with an increase in cell size, that is, pillar height as well as interpillar distance, and approaches a plateau as the pillar height and the interpillar distance approach the critical lengths for ballistic thermal transport in SWCNT and single layer graphene. The results indicate that the thermal transport characteristics of these SWCNT-graphene hybrid structures can be tuned by controlling the SWCNT-graphene junction characteristics as well as the unit cell dimensions.

  8. A novel time dependent gamma evaluation function for dynamic 2D and 3D dose distributions.

    Science.gov (United States)

    Podesta, Mark; Persoon, Lucas C G G; Verhaegen, Frank

    2014-10-21

    Modern external beam radiotherapy requires detailed verification and quality assurance so that confidence can be placed on both the delivery of a single treatment fraction and on the consistency of delivery throughout the treatment course. To verify dose distributions, a comparison between prediction and measurement must be made. Comparisons between two dose distributions are commonly performed using a Gamma evaluation which is a calculation of two quantities on a pixel by pixel basis; the dose difference, and the distance to agreement. By providing acceptance criteria (e.g. 3%, 3 mm), the function will find the most appropriate match within its two degrees of freedom. For complex dynamic treatments such as IMRT or VMAT it is important to verify the dose delivery in a time dependent manner and so a gamma evaluation that includes a degree of freedom in the time domain via a third parameter, time to agreement, is presented here. A C++ (mex) based gamma function was created that could be run on either CPU and GPU computing platforms that would allow a degree of freedom in the time domain. Simple test cases were created in both 2D and 3D comprising of simple geometrical shapes with well-defined boundaries varying over time. Changes of varying magnitude in either space or time were introduced and repeated gamma analyses were performed varying the criteria. A clinical VMAT case was also included, artificial air bubbles of varying size were introduced to a patient geometry, along with shifts of varying magnitude in treatment time. For all test cases where errors in distance, dose or time were introduced, the time dependent gamma evaluation could accurately highlight the errors.The time dependent gamma function presented here allows time to be included as a degree of freedom in gamma evaluations. The function allows for 2D and 3D data sets which are varying over time to be compared using appropriate criteria without penalising minor offsets of subsequent radiation fields

  9. Evaluation of failing hemodialysis fistulas with multidetector CT angiography: Comparison of different 3D planes

    Energy Technology Data Exchange (ETDEWEB)

    Karadeli, E. [Department of Radiology, Baskent University, Faculty of Medicine, Ankara (Turkey); Tarhan, N.C. [Department of Radiology, Baskent University, Faculty of Medicine, Ankara (Turkey)], E-mail: caglat@baskent-ank.edu.tr; Ulu, E.M. Kayahan; Tutar, N.U. [Department of Radiology, Baskent University, Faculty of Medicine, Ankara (Turkey); Basaran, O. [Department of General Surgery, Baskent University, Faculty of Medicine, Ankara (Turkey); Coskun, M.; Niron, E.A. [Department of Radiology, Baskent University, Faculty of Medicine, Ankara (Turkey)

    2009-01-15

    Purpose: To evaluate failing hemodialysis fistula complications using 16-detector MDCTA, and to assess the accuracies of different 3D planes. Materials and methods: Thirty patients (16 men, 14 women, aged 27-79 years) were referred for hemodialysis access dysfunction. Thirty-one MDCTA exams were done prior to fistulography. For MDCTA, contrast was administered (2 mL/kg at 5 mL/s) via a peripheral vein in the contralateral arm. Axial MIP, coronal MIP, and VRT images were constructed. Venous complications were evaluated on axial source images, on each 3D plane, and on all-planes together. Results were analyzed using McNemar test. Results: Axial MIP, VRT and all-planes evaluations were most sensitive for fistula site detection (93%). Coronal MIP had the highest sensitivity, specificity and accuracy (35%, 96%, and 85%, respectively) for detecting venous stenosis. VRT and all-planes had the highest sensitivity and accuracy for detecting aneurysms (100%). All-planes and axial MIP were most sensitive for detecting venous occlusion (61% and 54%). Comparisons of detection frequencies for each venous pathology between the five categories of MDCTA revealed no significant differences (P > 0.05). MDCTA additionally showed 3 partially thrombosed aneurysms, 4 anastomosis site stenosis and 12 arterial complications. Conclusion: MDCTA overall gives low sensitivity for detection of central vein stenosis and moderate sensitivity for occlusion. For most pathology, all-planes evaluation of MDCTA gives highest sensitivity and accuracy rates when compared to other planes. For venous stenosis and occlusion, MDCTA should be considered when ultrasonography and fistulography are inconclusive. MDCTA is helpful in identifying aneurysms, collaterals, partial venous thromboses and additional arterial, anastomosis site pathologies.

  10. Evaluation of 3D printing and its potential impact on biotechnology and the chemical sciences.

    Science.gov (United States)

    Gross, Bethany C; Erkal, Jayda L; Lockwood, Sarah Y; Chen, Chengpeng; Spence, Dana M

    2014-04-01

    Nearing 30 years since its introduction, 3D printing technology is set to revolutionize research and teaching laboratories. This feature encompasses the history of 3D printing, reviews various printing methods, and presents current applications. The authors offer an appraisal of the future direction and impact this technology will have on laboratory settings as 3D printers become more accessible.

  11. Thermal-Aware Design and Runtime Management of 3D Stacked Multiprocessors

    NARCIS (Netherlands)

    Kumar, S.S.

    2015-01-01

    The sustained increase in computational performance demanded by next-generation applications drives the increasing core counts of modern multiprocessor systems. However, in the dark silicon era, the performance levels and integration density of such systems is limited by thermal constraints of their

  12. Can 3D ultrasound identify trochlea dysplasia in newborns? Evaluation and applicability of a technique

    International Nuclear Information System (INIS)

    Highlights: • We evaluated a possible screening method for trochlea dysplasia. • 3D ultrasound was used to perform the measurements on standardized axial planes. • The evaluation of the technique showed comparable results to other studies. • This technique may be used as a screening technique as it is quick and easy to perform. - Abstract: Femoro-patellar dysplasia is considered as a significant risk factor of patellar instability. Different studies suggest that the shape of the trochlea is already developed in early childhood. Therefore early identification of a dysplastic configuration might be relevant information for the treating physician. An easy applicable routine screening of the trochlea is yet not available. The purpose of this study was to establish and evaluate a screening method for femoro-patellar dysplasia using 3D ultrasound. From 2012 to 2013 we prospectively imaged 160 consecutive femoro-patellar joints in 80 newborns from the 36th to 61st gestational week that underwent a routine hip sonography (Graf). All ultrasounds were performed by a pediatric radiologist with only minimal additional time to the routine hip ultrasound. In 30° flexion of the knee, axial, coronal, and sagittal reformats were used to standardize a reconstructed axial plane through the femoral condyle and the mid-patella. The sulcus angle, the lateral-to-medial facet ratio of the trochlea and the shape of the patella (Wiberg Classification) were evaluated. In all examinations reconstruction of the standardized axial plane was achieved, the mean trochlea angle was 149.1° (SD 4.9°), the lateral-to-medial facet ratio of the trochlea ratio was 1.3 (SD 0.22), and a Wiberg type I patella was found in 95% of the newborn. No statistical difference was detected between boys and girls. Using standardized reconstructions of the axial plane allows measurements to be made with lower operator dependency and higher accuracy in a short time. Therefore 3D ultrasound is an easy

  13. Can 3D ultrasound identify trochlea dysplasia in newborns? Evaluation and applicability of a technique

    Energy Technology Data Exchange (ETDEWEB)

    Kohlhof, Hendrik, E-mail: Hendrik.Kohlhof@ukb.uni-bonn.de [Clinic for Orthopedics and Trauma Surgery, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn (Germany); Heidt, Christoph, E-mail: Christoph.heidt@kispi.uzh.ch [Department of Orthopedic Surgery, University Children' s Hospital Zurich, Steinwiesstrasse 74, 8032 Switzerland (Switzerland); Bähler, Alexandrine, E-mail: Alexandrine.baehler@insel.ch [Department of Pediatric Radiology, University Children' s Hospital Berne, Freiburgstrasse 18, 3010 Berne (Switzerland); Kohl, Sandro, E-mail: sandro.kohl@insel.ch [Department of Orthopedic Surgery, University Hospital Berne, Freiburgstrasse 18, 3010 Berne (Switzerland); Gravius, Sascha, E-mail: sascha.gravius@ukb.uni-bonn.de [Clinic for Orthopedics and Trauma Surgery, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn (Germany); Friedrich, Max J., E-mail: Max.Friedrich@ukb.uni-bonn.de [Clinic for Orthopedics and Trauma Surgery, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn (Germany); Ziebarth, Kai, E-mail: kai.ziebarth@insel.ch [Department of Orthopedic Surgery, University Hospital Berne, Freiburgstrasse 18, 3010 Berne (Switzerland); Stranzinger, Enno, E-mail: Enno.Stranzinger@insel.ch [Department of Pediatric Radiology, University Children' s Hospital Berne, Freiburgstrasse 18, 3010 Berne (Switzerland)

    2015-06-15

    Highlights: • We evaluated a possible screening method for trochlea dysplasia. • 3D ultrasound was used to perform the measurements on standardized axial planes. • The evaluation of the technique showed comparable results to other studies. • This technique may be used as a screening technique as it is quick and easy to perform. - Abstract: Femoro-patellar dysplasia is considered as a significant risk factor of patellar instability. Different studies suggest that the shape of the trochlea is already developed in early childhood. Therefore early identification of a dysplastic configuration might be relevant information for the treating physician. An easy applicable routine screening of the trochlea is yet not available. The purpose of this study was to establish and evaluate a screening method for femoro-patellar dysplasia using 3D ultrasound. From 2012 to 2013 we prospectively imaged 160 consecutive femoro-patellar joints in 80 newborns from the 36th to 61st gestational week that underwent a routine hip sonography (Graf). All ultrasounds were performed by a pediatric radiologist with only minimal additional time to the routine hip ultrasound. In 30° flexion of the knee, axial, coronal, and sagittal reformats were used to standardize a reconstructed axial plane through the femoral condyle and the mid-patella. The sulcus angle, the lateral-to-medial facet ratio of the trochlea and the shape of the patella (Wiberg Classification) were evaluated. In all examinations reconstruction of the standardized axial plane was achieved, the mean trochlea angle was 149.1° (SD 4.9°), the lateral-to-medial facet ratio of the trochlea ratio was 1.3 (SD 0.22), and a Wiberg type I patella was found in 95% of the newborn. No statistical difference was detected between boys and girls. Using standardized reconstructions of the axial plane allows measurements to be made with lower operator dependency and higher accuracy in a short time. Therefore 3D ultrasound is an easy

  14. Evaluation and application of 3D lung warping and registration model using HRCT images

    Science.gov (United States)

    Fan, Li; Chen, Chang W.; Reinhardt, Joseph M.; Hoffman, Eric A.

    2001-05-01

    Image-based study of structure-function relationships is a challenging problem in that the structure or region of interest may vary in position and shape on images captured over time. Such variation may be caused by the change in body posture or the motion of breathing and heart beating. Therefore, the structure or region of interest should be registered before any further regional study can be carried out. In this paper, we propose a novel approach to study the structure-function relationship of ventilation using a previously developed 3D lung warping and registration model. First, we evaluate the effectiveness of the lung warping and registration model using a set of criteria, including apparent lung motion patterns and ground truths. Then, we study the ventilation by integrating the warping model with air content calibration. The warping model is applied to three CT lung data sets, obtained under volume control of FRC, 40% and 75% vital capacity (VC). Dense displacement fields are obtained to represent deformation between different lung volume steps. For any specific region of interest, we first register it between images over time using the dense displacement, and then estimate the corresponding regional inspired air content. Assessments include change of regional volume during inspiration, change of regional air content, and the distribution of regional ventilation. This is the first time that 3D warping of lung images is applied to assess clinically significant pulmonary functions.

  15. A Numerical Study on the Thermal Conductivity of 3D Woven C/C Composites at High Temperature

    Science.gov (United States)

    Shigang, Ai; Rujie, He; Yongmao, Pei

    2015-12-01

    Experimental data for Carbon/Carbon (C/C) constituent materials are combined with a three dimensional steady state heat transfer finite element analysis to demonstrate the average in-plane and out-of-plane thermal conductivities (TCs) of C/C composites. The finite element analysis is carried out at two distinct length scales: (a) a micro scale comparable with the diameter of carbon fibres and (b) a meso scale comparable with the carbon fibre yarns. Micro-scale model calculate the TCs at the fibre yarn scale in the three orthogonal directions ( x, y and z). The output results from the micro-scale model are then incorporated in the meso-scale model to obtain the global TCs of the 3D C/C composite. The simulation results are quite consistent with the theoretical and experimental counterparts reported in references. Based on the numerical approach, TCs of the 3D C/C composite are calculated from 300 to 2500 K. Particular attention is given in elucidating the variations of the TCs with temperature. The multi-scale models provide an efficient approach to predict the TCs of 3D textile materials, which is helpful for the thermodynamic property analysis and structure design of the C/C composites.

  16. GeoFlow: 3D numerical simulation of supercritical thermal convective states

    Energy Technology Data Exchange (ETDEWEB)

    Futterer, B; Egbers, C [Department of Aerodynamics and Fluid Mechanics, Brandenburg University of Technology Cottbus, Siemens-Halske-Ring 14, 03046 Cottbus (Germany); Hollerbach, R [Department of Applied Mathematics, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT (United Kingdom)], E-mail: futterer@tu-cottbus.de

    2008-11-01

    'GeoFlow' is a thermal convection experiment in rotating spherical shell geometry, which is going to take place in microgravity environment of International Space Station. We present numerical preliminary studies of the spherical Rayleigh-Benard problem under an artificial central force field. Numerical simulation is done with a pseudospectral method. Special focus here is the simulation of flow states at selected parameter points of Rayleigh and Taylor number of a defined plan for experimental runs on ISS. One loop will contain thermal convection without rotation, i.e. rising temperature gradient between inner and outer sphere. Another loop investigates convection superimposed by rotation, i.e. fixing temperature gradient and then rising rotation rate. In such cases different transitions are expected to be observed. Just rising Rayleigh number shows different stable states depending on initial conditions. Fixing Rayleigh number and then rising up Taylor number leads to traverse of different convective states showing rich dynamics of the system.

  17. 3D modeling and simulation of the thermal performance of solid cyclotron targets

    Energy Technology Data Exchange (ETDEWEB)

    Avila-Rodriguez, M.A.; Sader, J.A.; McQuarrie, S.A. [Alberta Univ., Edmonton PET Centre, Cross Cancer Institute, AB (Canada); McQuarrie, S.A. [Alberta Univ., Faculty of Medicine and Dentistry, Div. of Oncologic Imaging, Edmonton, AB (Canada)

    2007-07-01

    COMSOL Multiphysics was used to model and simulate the thermal performance of solid targets irradiated with charged particles. Parametric solutions for beam power densities in the range from 1.5 10{sup 5} to 1.5 10{sup 6} W/m{sup 2} and cooling water flow velocities from 0.2 to 4.0 m/s were obtained for different plate materials. Results showed that materials with a high thermal conductivity to heat capacity ratio behave better in cooling dynamic systems requiring fast dissipation of heat. Results also showed that water flow rates greater than 2.6 L/min do not noticeably improve the heat dissipation of solid targets irradiated with charged particles. (authors)

  18. Thermal Conductivity of 3D CNT-Polymer Composites with Controlled Dispersion

    Science.gov (United States)

    Klittich, Mena; Wang, Xue; Dhinojwala, Ali

    The high thermal conductivity of isolated carbon nanotubes (CNTs) has inspired its use as a thermal filler for insulative polymers. However, the performance of these composites has consistently been sub par. Extensive analyses of these complex systems have resulted in the conclusion that resistance at the CNT/polymer interface due to phonon mismatch and poor physical binding, as well as the weakly bonded tube-tube interactions restrict the effectiveness of CNTs in practice. Experimental comparisons of CNT treatments, coatings, functionalization, and interactions with various polymers have proved challenging, due to the interconnected nature of the composite properties. Here, we have reversed the paradigm and used a constant CNT structure that is then modified post-growth to allow for direct comparisons of polymer composites.

  19. Full 3-D numerical modeling of borehole electric image logging and the evaluation model of fracture

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A full 3-D finite element method numerical modeling program is written based on the principle and technical specification of borehole electric image well logging tool. The response of well logging is computed in the formation media model with a single fracture. The effect of changing fracture aperture and resistivity ratio to the logging response is discussed. The identification ability for two parallel fractures is also present. A quantitative evaluation formula of fracture aperture from borehole electric image logging data is set up. A case study of the model well is done to verify the accuracy of the for-mula. The result indicates that the formula is more accurate than the foreign one.

  20. 3D scanning applied in the evaluation of large plastic deformation

    Directory of Open Access Journals (Sweden)

    Márcio Eduardo Silveira

    2012-01-01

    Full Text Available Crash test are experimental studies demanded by specialized agencies in order to evaluate the performance of a component (or entire vehicle when subjected to an impact. The results, often highly destructive, produce large deformations in the product. The use of numerical simulation in initial stages of a project is essential to reduce costs. One difficulty in validating numerical results involves the correlation between the level and the deformation mode of the component, since it is a highly nonlinear simulation in which various parameters can affect the results. The main objective of this study was to propose a methodology to correlate the result of crash tests of a fuel tank with the numerical simulations, using an optical 3D scanner. The results are promising, and the methodology implemented would be used for any products that involve large deformations.

  1. Evaluation of single photon and Geiger mode Lidar for the 3D Elevation Program

    Science.gov (United States)

    Stoker, Jason M.; Abdullah, Qassim; Nayegandhi, Amar; Winehouse, Jayna

    2016-01-01

    Data acquired by Harris Corporation’s (Melbourne, FL, USA) Geiger-mode IntelliEarth™ sensor and Sigma Space Corporation’s (Lanham-Seabrook, MD, USA) Single Photon HRQLS sensor were evaluated and compared to accepted 3D Elevation Program (3DEP) data and survey ground control to assess the suitability of these new technologies for the 3DEP. While not able to collect data currently to meet USGS lidar base specification, this is partially due to the fact that the specification was written for linear-mode systems specifically. With little effort on part of the manufacturers of the new lidar systems and the USGS Lidar specifications team, data from these systems could soon serve the 3DEP program and its users. Many of the shortcomings noted in this study have been reported to have been corrected or improved upon in the next generation sensors.

  2. 3D transient thermal modelling of laser microchannel fabrication in lime-soda glass

    OpenAIRE

    Issa, Ahmad,; Brabazon, Dermot; Hashmi, Saleem

    2008-01-01

    Laser-fabricated microchannels in glass offer a wide range of bioengineering and telecommunication applications. A 1.5 kW CO2 laser with 10.6 μm wavelength was used in this study to fabricate micorchannels on the surface of soda-lime glass sheets. A thermal model of the process was developed based on transient heat conduction due to a pulsed heat input. The resulting equation predicted the temperature distribution in the regions surrounding the laser focus. Temperature – time curves were draw...

  3. A Novel Methodology for Thermal Aware Silicon Area Estimation for 2D & 3D MPSoCs

    Directory of Open Access Journals (Sweden)

    Vinod Pangracious

    2012-01-01

    Full Text Available In a multiprocessor system on chip (MPSoC IC the processor is one of the highest heat dissipating devices. The temperature generated in an IC may vary with floor plan of the chip. This paper proposes an integration and thermal analysis methodology to extract the peak temperature and temperature distribution of 2-dimensional and 3-dimensional multiprocessor system-on-chip. As we know the peak temperature of chip increases in 3-dimensional structures compared to 2-dimensional ones due to the reduced space in intra-layer and inter-layer components. In sub-nanometre scale technologies, it is inevitable to analysis the heat developed in individual chip to extract the temperature distribution of the entire chip. With thetechnology scaling in new generation ICs more and more components are integrated to a smaller area. Along with the other parameters threshold voltage is also scaled down which results in exponential increase in leakage current. This has resulted in rise in hotspot temperature value due to increase inleakage power. In this paper, we have analysed the temperature developed in an IC with four identical processors at 2.4 GHz in different floorplans. The analysis has been done for both 2D and 3D arrangements. In the 3D arrangement, a three layered structure has been considered with two Silicon layers and a thermal interface material (TIM in between them. Based on experimental results the paperproposes a methodology to reduce the peak temperature developed in 2D and 3D integrated circuits .

  4. Methodology for thermal budget reduction of SPER down to 450 °C for 3D sequential integration

    Science.gov (United States)

    Luce, F. P.; Pasini, L.; Sklénard, B.; Mathieu, B.; Licitra, C.; Batude, P.; Mazen, F.

    2016-03-01

    3D sequential integration enables the full use of the third dimension thanks to its unique contact density far above the possibilities of 3D packaging solutions. However, as the transistors are sequentially stacked over each other, the thermal budget allowed for the fabrication of the top transistor is limited by the maximal temperature accepted by the already made bottom one. It was previously described that a thermal budget of T > 500 °C is enough to degrade the bottom transistors performance. So the technological challenge is to develop low temperature routines for the fabrication of the top devices. For that, different processes have to be adapted, mainly the dopant activation step, where the T > 1000 °C spike annealing must be replaced. In this contribution, we present the feasibility to dope by solid phase epitaxial regrowth (SPER) at 450 °C thin Si films (22 nm) containing high dopant concentration of 5 × 1020 at/cm3. For n- and p-type dopants, the 450 °C SPER rendered low sheet resistance values, as low as the ones obtained with the high temperature activation method.

  5. Thermal-hydraulic system study of a high pressure, high temperature helium loop using RELAP5-3D code

    International Nuclear Information System (INIS)

    Highlights: ► A thermal-hydraulic system analysis for a high pressure, high temperature helium loop has been investigated. ► The loop belongs to the Helium Loop Karlsruhe (HELOKA) facility, which contains the European Helium Cooled Pebble Beds Test Blanket Module (HCPB TBM) as the test module. ► The loop including all components has been modeled using the system code REALP5-3D, and the main control strategy has been implemented as well. ► With this model, the loop dynamics in conditions relevant for blanket module operation have been demonstrated. - Abstract: The thermal-hydraulic system analysis for the Helium Loop Karlsruhe (HELOKA) facility, a high pressure, high temperature experimental helium loop having the European Helium Cooled Pebble Beds Test Blanket Module (HCPB TBM) as the test module, was investigated. Using the system code REALP5-3D, all components in the loop are modeled as well as the main control strategy. With this model, the loop dynamics in conditions relevant for blanket module operation are simulated and analyzed.

  6. A new finite volume discretization scheme to solve 3D incompressible thermal flows on unstructured meshes

    Energy Technology Data Exchange (ETDEWEB)

    Perron, Sebastien [ARDC, Alcan, Applied Science Research Group, 1955 Mellon Blvd, P.O. Box 1250, Quebec G7S 4K8, Jonquiere (Canada); Boivin, Sylvain [Universite du Quebec a Chicoutimi, 555 Boulevard de l' universite, Quebec G7H 2B1, Chicoutimi (Canada); Herard, Jean-Marc [DRD, Electricite de France, 6, quai Watier 78400, Chatou (France)

    2004-09-01

    We present a new method to solve incompressible thermal flows and the transport of scalar quantities. It is a finite volume scheme for unstructured meshes whose time discretization is based upon the fractional time step method. The governing equations are discretized using a collocated, cell-centered arrangement of velocity and pressure. The solution variables are stored at the cell-circum-centers. This scheme is convergent, stable and allows computing solutions that does not violate the maximum principle when it applies. Theoretical results and numerical properties of the scheme are provided. Predictions of Boussinesq fluid flow, flow past a cylinder and heat transport in a cylinder are performed to validate the method. (authors)

  7. Fabrication of 3D Microfluidic Devices by Thermal Bonding of Thin Poly(methyl methacrylate) Films

    KAUST Repository

    Perez, Paul

    2012-07-01

    The use of thin-film techniques for the fabrication of microfluidic devices has gained attention over the last decade, particularly for three-dimensional channel structures. The reasons for this include effective use of chip volume, mechanical flexibility, dead volume reduction, enhanced design capabilities, integration of passive elements, and scalability. Several fabrication techniques have been adapted for use on thin films: laser ablation and hot embossing are popular for channel fabrication, and lamination is widely used for channel enclosure. However, none of the previous studies have been able to achieve a strong bond that is reliable under moderate positive pressures. The present work aims to develop a thin-film process that provides design versatility, speed, channel profile homogeneity, and the reliability that others fail to achieve. The three building blocks of the proposed baseline were fifty-micron poly(methyl methacrylate) thin films as substrates, channel patterning by laser ablation, and device assembly by thermal-fusion bonding. Channel fabrication was characterized and tuned to produce the desired dimensions and surface roughness. Thermal bonding was performed using an adapted mechanical testing device and optimized to produce the maximum bonding strength without significant channel deformation. Bonding multilayered devices, incorporating conduction lines, and integrating various types of membranes as passive elements demonstrated the versatility of the process. Finally, this baseline was used to fabricate a droplet generator and a DNA detection chip based on micro-bead agglomeration. It was found that a combination of low laser power and scanning speed produced channel surfaces with better uniformity than those obtained with higher values. In addition, the implemented bonding technique provided the process with the most reliable bond strength reported, so far, for thin-film microfluidics. Overall, the present work proved to be versatile

  8. CT colonography: evaluation of two 3D algorithms in a screening population

    International Nuclear Information System (INIS)

    Purpose: the purpose of this multicenter study was to compare a dissection display and an endoluminal display for CT colonography (CTC) by means of detection rates and evaluation time in a screening collective. Materials and methods: 4 blinded readers evaluated CTC datasets from 42 patients with 55 endoscopically confirmed polyps. The datasets were read in a randomized order using two different 3D visualization methods (endoluminal view vs. dissection display; EBW 2.0.1, Philips Medical Systems, Best/NL). Patients underwent cathartic cleansing as well as stool and fluid tagging. All readers except one were experienced in performing CTC. The per-lesion/per-patient sensitivity, per-patient specificity, and evaluation time were calculated. Results: the overall per-lesion sensitivity using the dissection display (and endoluminal view) was 60% (53%) for reader 1, 58% (60%) for reader 2, 67% (71%) for reader 3 and 55% (58%) for reader 4. The per-patient sensitivity using the dissection display (and endoluminal view) was 85% (85%) for reader 1, 80% (85%) for reader 2, 95% (90%) for reader 3 and 80% (80%) for reader 4. The per-patient specificity was 68% with dissection view (77% endoluminal view) for reader 1, 82% (82%) for reader 2, 59% (59%) for reader 3 and 82% (73%) for reader 4. The experienced readers were significantly faster using the perspective-filet view. (orig.)

  9. CCTV Coverage Index Based on Surveillance Resolution and Its Evaluation Using 3D Spatial Analysis

    Directory of Open Access Journals (Sweden)

    Kyoungah Choi

    2015-09-01

    Full Text Available We propose a novel approach to evaluating how effectively a closed circuit television (CCTV system can monitor a targeted area. With 3D models of the target area and the camera parameters of the CCTV system, the approach produces surveillance coverage index, which is newly defined in this study as a quantitative measure for surveillance performance. This index indicates the proportion of the space being monitored with a sufficient resolution to the entire space of the target area. It is determined by computing surveillance resolution at every position and orientation, which indicates how closely a specific object can be monitored with a CCTV system. We present full mathematical derivation for the resolution, which depends on the location and orientation of the object as well as the geometric model of a camera. With the proposed approach, we quantitatively evaluated the surveillance coverage of a CCTV system in an underground parking area. Our evaluation process provided various quantitative-analysis results, compelling us to examine the design of the CCTV system prior to its installation and understand the surveillance capability of an existing CCTV system.

  10. Multi-scale uncertainty and sensitivity analysis of the TALL-3D experiment using thermal-hydraulic coupled codes

    International Nuclear Information System (INIS)

    The simulation of complex thermal-hydraulic phenomena is a challenging task. On one hand Computational Fluid Dynamics (CFD) codes allow a fine resolution of 3D phenomena but have a computational cost which is still prohibitive for some applications. On the other hand, System Analysis codes are fast running but cannot account for 3D phenomena. The coupling of these two approaches provides a tool which combines their advantages. In the context of the European THINS Project (7th Framework Program) the Gesellschaft für Anlagen- und Reaktorsicherheit mbH (GRS) developed a coupling between ANSYS CFX and ATHLET. The validation of this coupled code is to be performed with the help of experimental data provided by KTH (Sweden), which has built the TALL-3D facility for this purpose. This facility investigates the transition from forced to natural circulation of the Lead-Bismuth Eutectic (LBE) in a pool connected to a 3-leg primary circuit with two heaters and a heat exchanger. TUM is responsible for the Uncertainty and Sensitivity Analysis (USA) of the coupled ATHLET-CFX simulations in the THINS Project. The influence of modeling uncertainty on the simulation results needs to be assessed because it can significantly impair their accuracy. USA is a powerful tool to assess the model output variability resulting from modeling uncertainty (Uncertainty Analysis) and to identify and rank the influential model input parameters (Sensitivity Analysis). TUM has developed a computational framework to propagate modeling uncertainty through coupled Systems Analysis – Computational Fluid Dynamics (CFD) codes. This framework is being applied to the simulation of the experiments performed on the TALL-3D facility. The uncertainty methodology used is based on the statistical sampling of the uncertain inputs and models used by the two codes, its propagation through coupled calculations, and the final processing of the output sample of variables of interest with non-parametric statistical

  11. Accuracy evaluation of initialization-free registration for intraoperative 3D-navigation

    International Nuclear Information System (INIS)

    Purpose An initialization-free approach for perioperative registration in functional endoscopic sinus surgery (FESS) is sought. The quality of surgical navigation relies on registration accuracy of preoperative images to the patient. Although landmark-based registration is fast, it is prone to human operator errors. This study evaluates the accuracy of two well-known methods for segmentation of the occipital bone from CT-images for use in surgical 3D-navigation. Method The occipital bone was segmented for registration without pre-defined correspondences, with the iterative closest point algorithm (ICP). The thresholding plus marching cubes segmentation (TMCS), and the deformable model segmentation (DMS) were compared quantitatively by overlaying the areas of the segmentations in cross-sectional slices, and visually by displaying the pointwise distances between the segmentations in a three-dimensional distance map relative to an expert manual segmentation, taken as a ''ground truth''. Results Excellent correspondence between the two methods was achieved; the results showed, however, that the TMCS is closer to the ''ground truth''. This is due to the sub-voxel accuracy of the marching cubes algorithm by definition, and the sensitivity of the DMS method to the choice of parameters. The DMS approach, as a gradient-based method, is insensitive to the thresholding initialization. For noisy images and soft tissue delineation a gradient-based method, like the deformable model, performs better. Both methods correspond within minute differences less than 4%. Conclusion These results will allow further minimization of human interaction in the planning phase for intraoperative 3D-navigation, by allowing to automatically create surface patches for registration purposes, ultimately allowing to build an initialization-free, fully automatic registration procedure for navigated Ear-, Nose-, Throat- (ENT) surgery. (orig.)

  12. Comparative evaluation between the Vitapan Classical and 3D-Master color scales

    Directory of Open Access Journals (Sweden)

    Rubens da Rocha Portal Junior

    2008-01-01

    Full Text Available Objective: To evaluate the use of two scales as regard efficiency of color selection and the selection technique used by dental surgeons that practice in the municipality of Belém in the State of Pará, and last year Dentistry students at the Centro Universitário do Pará – Brazil. Method: Four healthy maxillary anterior teeth were chosen in two volunteers. The teeth were submitted to color selection by threeprofessionals experienced in dental prosthesis. Among the interviewees, there were 30 were professionals and 15 academics, and the scales analyzed were Vitapan Classical and Vitapan 3D-Master. A questionnaire containing seven questions on the color selectiontechnique was applied, in which the following factors were analyzed: room, light source, ideal time, and whether the teeth were humid,as well as other requirements for correct color selection. The data obtained were submitted to the Mann-Whitney nonparametric test (5% as it concerned an independent variable and subjective data. Results: The results showed that there were no statistically significant differences between the scales researched when color selection wasmade with an unsuitable technique and that dental surgeons and academics need to improve their color selection technique. Conclusion: It was concluded that there is no difference between the use of the Vitapan Classical and Vitapan 3D-Master scales when thetechnique used does not follow ideal selection patterns, the number of errors being statistically higher than the number of correct choices, indicating a need for technical improvement in color selection by dental surgeons and academics.

  13. LBP and lower limb discrepancy: 3D evaluation of postural rebalancing via underfoot wedge correction.

    Science.gov (United States)

    D'Amico, Moreno; Roncoletta, Piero; Di Felice, Francesca; Porto, Daniele; Bellomo, Rosagrazia; Saggini, Raoul

    2012-01-01

    Leg Length Discrepancy (LLD) is very often associated to Low Back Pain (LBP), but still controversial is the use of underfoot wedge correction (heel rise) to re-balance pelvis and trunk posture. In a review of our last 5 years clinical activity we observed that more than 70% out of 300 LBP patients presented a LLD. In more than 80 % we ascertained, via Baropodography, the presence of underfoot asymmetric load, during standing. More durable therapy recovery effect has been observed when LLD correction had been adopted. These reasons led us to start a study to assess if a Full 3D multifactorial Posture evaluation approach, by means of Opto-electronic device associated to foot pressure maps recording, was able to quantitatively discriminate the clinically observed phenomena. On a 94 LBP (av. age 46.3±16 Y range 15-82 Y) patients sample, 83 (88%) have been found to improve posture when LLD was corrected. The 94 patients showed a mean lower limb discrepancy of μ=8±3.2mm associated to a mean scoliotic lumbar curve μ=10.5°±5.1° Cobb (frontal plane), mean Spinal offset μ=6.6±4.9mm and mean Global offset 10.7±8.8mm. The applied paired t-test comparison (indifferent vs. corrected orthostasis) showed significant (p < 0.05) postural improvements could be obtained in the whole or in a part of the considered parameters, both in rebalancing and in spine deformities reduction after the application of suitable under-foot wedge. The joint 3D opto-electronic and foot pressure map approach proved to be effective to control several clinical parameters with statistical significance.

  14. Ultrasound and 3D Skin Imaging: Methods to Evaluate Efficacy of Striae Distensae Treatment

    Directory of Open Access Journals (Sweden)

    Mariella Bleve

    2012-01-01

    Full Text Available Background. Over time, the striae rubra develop into striae alba that appear white, flat, and depressed. It is very important to determine the optimum striae management. In order to evaluate the effectiveness of these therapies, objective measurement tools are necessary. Objective. The aim of this study is to evaluate if ultrasonography and PRIMOS can be used to obtain an objective assessment of stretch marks type and stage; furthermore, we aim to apply these techniques to evaluate the efficacy of a topical treatment. Methods. 20 volunteers were enrolled with a two-month study. A marketed cosmetic product was used as the active over one body area. The controlateral area with stretch marks was treated with a “placebo” formulation without active, as a control. The instrumental evaluation was carried out at the beginning of the trial (baseline values or 0, after 1 month (1, and at the end of the study (2. Results. PRIMOS was able to measure and document striae distensae maturation; furthermore, ultrasound imaging permitted to visualize and diagnose the striae. Statistical analysis of skin roughness demonstrated a statistically significant reduction of Rp value only in a treated group. In fact, the Rp value represented a maximum peak height in the area selected. These results demonstrated that after two months of treatment only the striae rubra can be treated successfully. Conclusions. This work demonstrated that the 22MHz ultrasound can diagnose stretch marks; PRIMOS device can detect and measure striae distensae type and maturation. Furthermore, the high-frequency ultrasound and the 3D image device, described in this work, can be successfully employed in order to evaluate the efficacy of a topical treatment.

  15. A 3D Osteoblast In Vitro Model for the Evaluation of Biomedical Materials

    Directory of Open Access Journals (Sweden)

    Luciana Restle

    2015-01-01

    Full Text Available Biomedical materials for bone therapy are usually assessed for their biocompatibility and safety employing animal models or in vitro monolayer cell culture assays. However, alternative in vitro models may offer controlled conditions closer to physiological responses and reduce animal testing. In this work, we developed a 3D spheroidal cell culture with potential to evaluate simultaneously material-cell and cell-cell interactions. Different cell densities of murine MC3T3-E1 preosteoblasts or human primary osteoblasts (HOb were used to determine the ideal procedure of spheroidal cultures and their adequacy to material testing. Cells were seeded on 96-well plates coated with agar and incubated in agitation from 1 to 7 days. Aggregate morphology was qualitatively evaluated considering the shape, size, repeatability, handling, and stability of spheroids. Higher cell densities induced more stable spheroids, and handling was considered appropriate starting from 2 × 104 cells. Confocal microscopy and Scanning Electron Microscopy indicate that most cells within the aggregate core are viable. Exposure to positive controls has shown a dose dependent cell death as measured by XTT assay. Aggregates were stable and presented good viability when employed on standardized testing of metallic and polymer-based biomaterials. Therefore, osteoblast spheroids may provide a promising tool for material screening and biocompatibility testing.

  16. Wave propagation analysis of quasi-3D FG nanobeams in thermal environment based on nonlocal strain gradient theory

    Science.gov (United States)

    Ebrahimi, Farzad; Barati, Mohammad Reza

    2016-09-01

    This article examines the application of nonlocal strain gradient elasticity theory to wave dispersion behavior of a size-dependent functionally graded (FG) nanobeam in thermal environment. The theory contains two scale parameters corresponding to both nonlocal and strain gradient effects. A quasi-3D sinusoidal beam theory considering shear and normal deformations is employed to present the formulation. Mori-Tanaka micromechanical model is used to describe functionally graded material properties. Hamilton's principle is employed to obtain the governing equations of nanobeam accounting for thickness stretching effect. These equations are solved analytically to find the wave frequencies and phase velocities of the FG nanobeam. It is indicated that wave dispersion behavior of FG nanobeams is significantly affected by temperature rise, nonlocality, length scale parameter and material composition.

  17. 3D FE Analysis of Thermal Behavior of Billet in Rod and Wire Hot Continuous Rolling Process

    Institute of Scientific and Technical Information of China (English)

    YUAN Si-yu; ZHANG Li-wen; LIAO Shu-lun; QI Min; ZHEN Yu; GUO Shu-qi

    2007-01-01

    An FE model was developed to study thermal behavior during the rod and wire hot continuous rolling process. The FE code MSC.Marc was used in the simulation using implicit static arithmetic. The whole rolling process of 30 passes was separated and simulated with several continuous 3D elastic-plastic FE models. A rigid pushing body and a data transfer technique were introduced into this model. The on-line experiments were conducted on 304 stainless steel and GCr15 steel hot continuous rolling process to prove the results of simulation by implicit static FEM. The results show that the temperature results of finite element simulations are in good agreement with experiments, which indicate that the FE model developed in this study is effective and efficient.

  18. Survey on RGB, 3D, Thermal, and Multimodal Approaches for Facial Expression Recognition: History, Trends, and Affect-Related Applications.

    Science.gov (United States)

    Corneanu, Ciprian Adrian; Simon, Marc Oliu; Cohn, Jeffrey F; Guerrero, Sergio Escalera

    2016-08-01

    Facial expressions are an important way through which humans interact socially. Building a system capable of automatically recognizing facial expressions from images and video has been an intense field of study in recent years. Interpreting such expressions remains challenging and much research is needed about the way they relate to human affect. This paper presents a general overview of automatic RGB, 3D, thermal and multimodal facial expression analysis. We define a new taxonomy for the field, encompassing all steps from face detection to facial expression recognition, and describe and classify the state of the art methods accordingly. We also present the important datasets and the bench-marking of most influential methods. We conclude with a general discussion about trends, important questions and future lines of research. PMID:26761193

  19. An Evaluation of 3D Woven Orthogonal Composites' Potential in the Automotive Supply Chain

    Science.gov (United States)

    Taylor, Dalia

    The automotive supply chain and its management can be a very complex process and comprises a long dynamic and complex network that consists of four primary segments: original equipment manufacturers (OEMs), first tier suppliers, sub tiers suppliers, and infrastructure suppliers. During the analysis of the current automotive industry it was identified that textile industry importance is considerable increasing as a part of the global automotive supply chain, because textile products are used for interior, exterior and even suspension parts and components. Automotive industry has an increasing demand for higher quality exterior panels with better functional properties and reduced weight. One of the main potentials for this demand is based on the three-dimensional woven composites technology innovations which can replace an existing technology. The new role of the textile industry could make important changes in the automotive supply chain industry, such as: changes in the size of the supply chain, the time to the market and the position of textile industry in the automotive supply chain structure. 3D composite materials from high performance fibers, such as glass and carbon, have been used for automotive applications in a limited way due to the low production rate and the lack of research and development. This research will contribute to the understanding of textile composites in transportation and the textile parameters that affect the performance characteristics of these materials. The research examines the performance characteristics of lighter and stronger 3D woven fabric composites made from fiberglass with the aim to improve fuel efficiency by reducing the total vehicle weight while maintaining safety standards. The performance characteristics of the 3D woven fabric composite can be designed by changing different construction parameters, such as picks density, pick roving linear density, arrangements of warp and z-yarns, and the number of warp and picks layers

  20. Thermal-Hydraulic Calculation for Simplified Fuel Assembly of Super Fast Reactor Using Two-Fluid Model Analysis Code ACE-3D

    International Nuclear Information System (INIS)

    To evaluate thermal hydraulic characteristics of a fuel assembly of supercritical water-cooled fast reactor (Super Fast Reactor), a simplified fuel assembly was analyzed with a three-dimensional two-fluid model analysis code ACE-3D which has been enhanced by Japan Atomic Energy Agency. In the ACE-3D code, the two-phase flow turbulent model based on the k-ε model were adopted. The analytical geometry simulates a 19-rod fuel assembly, which is a simplified geometry of the 271-rod fuel assembly and includes all three kinds of different subchannel types; (1): adjoining to the channel box, (2): next to type (1), and (3): located inside types (1) and (2). In this calculation, one-twelfth model is adopted as the computational domain taking advantage of symmetry. As the boundary conditions, mass velocity, inlet enthalpy and power per rod are to be the same as the steady state condition of the Super Fast Reactor. Cross-sectional local power distribution in the fuel assembly is set to be flat. Rod surface temperatures take peak values near the top of the rods. Maximum clad surface temperature (MCST) is observed at the position facing to the narrowest gap on the center rod near the outlet and the value is 902 K (629 deg. C). It was confirmed that the predicted MCST satisfies a thermal design criteria to ensure fuel and cladding integrity: the MCST should be less than 650 deg. C. (author)

  1. Evaluation of the correctness of a 3D recording device for mandibular functional movement in laboratory

    Science.gov (United States)

    Zhao, Tian; Sui, Huaxin; Yang, Huifang; Wang, Yong; Sun, Yuchun

    2015-07-01

    Objectives: To quantitatively evaluate the correctness of a computer binocular vision mandibular 3D trajectory recording device. Methods: A specialized target shooting paper was neatly pasted on a high-precision three-axis electronic translation stage. A linear one-way movement was set at a speed of 1 mm/s along the X, Y, and Z directions for a distance of 10 mm each. The coordinates of 3 pre-set target points were recorded at the start and end by a computer binocular vision system with a frequency of 10 FPS and stored in TXT format. The TXT files were imported to Imageware 13.0, and the straight-line lengths between the start and end were measured. The mean difference between each length and 10 mm were calculated to evaluate the correctness of the distance measurement. The linear movement and recording procedure was repeated 3 times, but the speed was changed to 5 mm/s to simulate the human mandibular movement speed. The trajectories of the 3 target points were fitted and the vertical dimensions from each track point to the fitted lines were measured. The mean difference was calculated between the vertical dimensions and 0 mm to evaluate the correctness of recording trajectories using this device. Results: The correctness of distance measurements of the points 1, 2, and 3 were 0.06 mm, 0.16 mm, and 0.08 mm, respectively. The correctness of the trajectories of the points 1, 2, and 3 were 0.11 mm, 0.11 mm, and 0.10 mm, respectively. Conclusion: Using this computer binocular vision device, the correctness of the recorded linear trajectories in the range of 10 mm was better than 0.20 mm.

  2. Accuracy of 3D white light scanning of abutment teeth impressions: evaluation of trueness and precision

    Science.gov (United States)

    Jeon, Jin-Hun; Kim, Hae-Young; Kim, Ji-Hwan

    2014-01-01

    PURPOSE This study aimed to evaluate the accuracy of digitizing dental impressions of abutment teeth using a white light scanner and to compare the findings among teeth types. MATERIALS AND METHODS To assess precision, impressions of the canine, premolar, and molar prepared to receive all-ceramic crowns were repeatedly scanned to obtain five sets of 3-D data (STL files). Point clouds were compared and error sizes were measured (n=10 per type). Next, to evaluate trueness, impressions of teeth were rotated by 10°-20° and scanned. The obtained data were compared with the first set of data for precision assessment, and the error sizes were measured (n=5 per type). The Kruskal-Wallis test was performed to evaluate precision and trueness among three teeth types, and post-hoc comparisons were performed using the Mann-Whitney U test with Bonferroni correction (α=.05). RESULTS Precision discrepancies for the canine, premolar, and molar were 3.7 µm, 3.2 µm, and 7.3 µm, respectively, indicating the poorest precision for the molar (Pteeth types were 6.2 µm, 11.2 µm, and 21.8 µm, respectively, indicating the poorest trueness for the molar (P=.007). CONCLUSION In respect to accuracy the molar showed the largest discrepancies compared with the canine and premolar. Digitizing of dental impressions of abutment teeth using a white light scanner was assessed to be a highly accurate method and provided discrepancy values in a clinically acceptable range. Further study is needed to improve digitizing performance of white light scanning in axial wall. PMID:25551007

  3. 3D simulation of the thermal and chemical plumes using open source software; Simulacion 3D de las plumas termica y quimica mediante software de codigo libre

    Energy Technology Data Exchange (ETDEWEB)

    Saenz Temino, J. L.; Lerones Martin, J.; Gonzalez Delgado, J.

    2013-07-01

    The interaction of thermal and chemical plumes in the region of the Irish Sea near the site has been simulated using a finite element model representative of the local hydrodynamic regime, concluding how the method of selected cooling, open cycle, is physically and environmentally feasible. Furthermore, tunnel lengths required for each scenario under discussion have been preliminarily defined, varying in a range from 1800 to 2300 meters for a unit (1 tunnel), 4400-6300 meters of two units (2 tunnels) and 8000 meters to three units (2 tunnels), depending on the chosen technology.

  4. Mammogram synthesis using a 3D simulation. II. Evaluation of synthetic mammogram texture

    International Nuclear Information System (INIS)

    We have evaluated a method for synthesizing mammograms by comparing the texture of clinical and synthetic mammograms. The synthesis algorithm is based upon simulations of breast tissue and the mammographic imaging process. Mammogram texture was synthesized by projections of simulated adipose tissue compartments. It was hypothesized that the synthetic and clinical texture have similar properties, assuming that the mammogram texture reflects the 3D tissue distribution. The size of the projected compartments was computed by mathematical morphology. The texture energy and fractal dimension were also computed and analyzed in terms of the distribution of texture features within four different tissue regions in clinical and synthetic mammograms. Comparison of the cumulative distributions of the mean features computed from 95 mammograms showed that the synthetic images simulate the mean features of the texture of clinical mammograms. Correlation of clinical and synthetic texture feature histograms, averaged over all images, showed that the synthetic images can simulate the range of features seen over a large group of mammograms. The best agreement with clinical texture was achieved for simulated compartments with radii of 4-13.3 mm in predominantly adipose tissue regions, and radii of 2.7-5.33 and 1.3-2.7 mm in retroareolar and dense fibroglandular tissue regions, respectively

  5. Preparation and Evaluation of Gelatin-Chitosan-Nanobioglass 3D Porous Scaffold for Bone Tissue Engineering

    Directory of Open Access Journals (Sweden)

    Kanchan Maji

    2016-01-01

    Full Text Available The aim of the present study was to prepare and characterize bioglass-natural biopolymer based composite scaffold and evaluate its bone regeneration ability. Bioactive glass nanoparticles (58S in the size range of 20–30 nm were synthesized using sol-gel method. Porous scaffolds with varying bioglass composition from 10 to 30 wt% in chitosan, gelatin matrix were fabricated using the method of freeze drying of its slurry at 40 wt% solids loading. Samples were cross-linked with glutaraldehyde to obtain interconnected porous 3D microstructure with improved mechanical strength. The prepared scaffolds exhibited >80% porosity with a mean pore size range between 100 and 300 microns. Scaffold containing 30 wt% bioglass (GCB 30 showed a maximum compressive strength of 2.2±0.1 MPa. Swelling and degradation studies showed that the scaffold had excellent properties of hydrophilicity and biodegradability. GCB 30 scaffold was shown to be noncytotoxic and supported mesenchymal stem cell attachment, proliferation, and differentiation as indicated by MTT assay and RUNX-2 expression. Higher cellular activity was observed in GCB 30 scaffold as compared to GCB 0 scaffold suggesting the fact that 58S bioglass nanoparticles addition into the scaffold promoted better cell adhesion, proliferation, and differentiation. Thus, the study showed that the developed composite scaffolds are potential candidates for regenerating damaged bone tissue.

  6. Evaluating Dense 3d Reconstruction Software Packages for Oblique Monitoring of Crop Canopy Surface

    Science.gov (United States)

    Brocks, S.; Bareth, G.

    2016-06-01

    Crop Surface Models (CSMs) are 2.5D raster surfaces representing absolute plant canopy height. Using multiple CMSs generated from data acquired at multiple time steps, a crop surface monitoring is enabled. This makes it possible to monitor crop growth over time and can be used for monitoring in-field crop growth variability which is useful in the context of high-throughput phenotyping. This study aims to evaluate several software packages for dense 3D reconstruction from multiple overlapping RGB images on field and plot-scale. A summer barley field experiment located at the Campus Klein-Altendorf of University of Bonn was observed by acquiring stereo images from an oblique angle using consumer-grade smart cameras. Two such cameras were mounted at an elevation of 10 m and acquired images for a period of two months during the growing period of 2014. The field experiment consisted of nine barley cultivars that were cultivated in multiple repetitions and nitrogen treatments. Manual plant height measurements were carried out at four dates during the observation period. The software packages Agisoft PhotoScan, VisualSfM with CMVS/PMVS2 and SURE are investigated. The point clouds are georeferenced through a set of ground control points. Where adequate results are reached, a statistical analysis is performed.

  7. Synthesis, characterization, antifungal evaluation and 3D-QSAR study of phenylhydrazine substituted tetronic acid derivatives.

    Science.gov (United States)

    Hu, Ying; Wang, Junjun; Lu, Aimin; Yang, Chunlong

    2014-08-15

    A series of 3-(1-(2-(substituted phenyl)hydrazinyl)alkylidene)furan-2,4(3H,5H)-diones were designed and prepared using two synthetic routes. Their structures were confirmed by FT-IR, (1)H NMR, (13)C NMR, MS, elemental analysis and single-crystal X-ray diffraction. Their bioactivity was evaluated against Botrytis cinerea in vitro. Most target compounds exhibited remarkable antifungal activity. Two compounds 7f and 7h were highly effective and their EC50 values were 0.241 μg/mL and 0.167 μg/mL, respectively, close to that of the control drug procymidone. 3D-QSAR studies of CoMFA and CoMSIA were carried out. Models with good predictive ability were generated with the cross validated q(2) values for CoMFA and CoMSIA being 0.565 and 0.823. Conventional r(2) values were 0.983 and 0.945, respectively. The results provided a practical tool for guiding the design and synthesis of novel and more potent tetronic acid derivatives containing substituted phenylhydrazine moiety. PMID:25042337

  8. 3D kinematic analysis and clinical evaluation of neck movements in patients with whiplash injury.

    Science.gov (United States)

    Antonaci, F; Bulgheroni, M; Ghirmai, S; Lanfranchi, S; Dalla Toffola, E; Sandrini, G; Nappi, G

    2002-09-01

    In recent decades whiplash injuries, being a major reason for compensation claims, have become increasingly important in forensic medicine. In view of this, a reliable diagnostic method of assessing cervical range of motion (ROM) is needed. The aim of the present study was to evaluate neck function with a 3D kinematic method compared with clinical evaluation in whiplash injury. Seventy consecutive patients (M/F = 18/52) with a history of whiplash injury (WH) and 46 healthy volunteers (M/F = 24/22), mean age, respectively 33 +/- 9 and 28 +/- 6 years (mean+/-SD) entered the study. Patients suffered from neck pain and/or unilateral headache. A computerized kinematic analysis of the ROM (Elite system) using passive markers and two infrared TV cameras was used. Clinical evaluation of active ROM was also performed both in patients and in 61 controls (M/F = 23/38; mean age 47 +/- 18 years). Thirty out of 70 patients were tested at the time of their first consultation (T0) and 6 months later (T6), and 12 were also followed up after a year (T12). All neck movements, except extension, were significantly reduced in WH subjects compared with controls, in particular lateral bending. Comparing ROM at T0, T6 and T12, no significant differences were found. A global index of motion (GIM), obtained by calculating the sum of ROM in absolute value for all the movements acquired, was significantly reduced in WH compared with control subjects. The interobserver reliability of the clinical evaluation was globally acceptable. On the basis of the clinical evaluation, a significantly reduced ROM was found in all movements in WH subjects compared with an age-matched population. Computing the number of impaired cervical movements (ICMs), a significantly higher number was observed in WH patients than in controls, showing a decreasing trend at T6 and T12, with a significant improvement at T6 vs. T0. The computerized study of neck ROM may constitute a useful tool in the evaluation of WH at

  9. Evaluation of the 3d Urban Modelling Capabilities in Geographical Information Systems

    Science.gov (United States)

    Dogru, A. O.; Seker, D. Z.

    2010-12-01

    Geographical Information System (GIS) Technology, which provides successful solutions to basic spatial problems, is currently widely used in 3 dimensional (3D) modeling of physical reality with its developing visualization tools. The modeling of large and complicated phenomenon is a challenging problem in terms of computer graphics currently in use. However, it is possible to visualize that phenomenon in 3D by using computer systems. 3D models are used in developing computer games, military training, urban planning, tourism and etc. The use of 3D models for planning and management of urban areas is very popular issue of city administrations. In this context, 3D City models are produced and used for various purposes. However the requirements of the models vary depending on the type and scope of the application. While a high level visualization, where photorealistic visualization techniques are widely used, is required for touristy and recreational purposes, an abstract visualization of the physical reality is generally sufficient for the communication of the thematic information. The visual variables, which are the principle components of cartographic visualization, such as: color, shape, pattern, orientation, size, position, and saturation are used for communicating the thematic information. These kinds of 3D city models are called as abstract models. Standardization of technologies used for 3D modeling is now available by the use of CityGML. CityGML implements several novel concepts to support interoperability, consistency and functionality. For example it supports different Levels-of-Detail (LoD), which may arise from independent data collection processes and are used for efficient visualization and efficient data analysis. In one CityGML data set, the same object may be represented in different LoD simultaneously, enabling the analysis and visualization of the same object with regard to different degrees of resolution. Furthermore, two CityGML data sets

  10. Qualification of the 3D thermal hydraulics model of the code system TRACE based on plant data

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, V.H.; Jager, W. [Forschungzentrum Karlsruhe (FZK), Institute of Reactor Safety (IRS) (Germany); Kozlowski, T. [Royal Institute of Technology (KTH), Stockholm (Sweden)

    2007-07-01

    In the frame of the VVER-1000 Coolant Transient Benchmark Phase-1 the coupled code RELAP5/PARCS has been extensively assessed. The Phase-2 of this benchmark - currently underway - focuses on both multidimensional thermal hydraulics phenomena within the reactor pressure vessel (RPV) such as coolant mixing and core physics. Hence it is an excellent opportunity to qualify the prediction capability of the new coupled code system TRACE/PARCS taking into account plant data obtained from the Kozloduy nuclear power plant unit 6. In addition a lose coupling of CFX with RELAP5 is applied for the posttest calculation of the coolant mixing experiment. The developed multidimensional models of the VVER-1000 reactor pressure vessel as well as the performed calculations using these models are described in some detail. The predicted results are in good agreement with the data. It was demonstrated that the chosen 3D-nodalization of the RPV is adequate for the description of the coolant mixing phenomena in a VVER-1000 reactor. In addition selected results of the code TRACE/PARCS for a postulated main steam line transient (MSLB) are given. The investigations have shown that the multidimensional neutronics and thermal hydraulic model developed for the RPV of the VVER-1000 reactor are well qualified and consequently they are ready for their integration into a overall plant model so that the exercise 3 of the Phase 2 can be investigated as next. (authors)

  11. 3D simulations of the non-thermal broad-band emission from young supernova remnants including efficient particle acceleration

    CERN Document Server

    Ferrand, Gilles; Safi-Harb, Samar

    2014-01-01

    Supernova remnants are believed to be the major contributors to Galactic cosmic rays. In this paper, we explore how the non-thermal emission from young remnants can be used to probe the production of energetic particles at the shock (both protons and electrons). Our model couples hydrodynamic simulations of a supernova remnant with a kinetic treatment of particle acceleration. We include two important back-reaction loops upstream of the shock: energetic particles can (i) modify the flow structure and (ii) amplify the magnetic field. As the latter process is not fully understood, we use different limit cases that encompass a wide range of possibilities. We follow the history of the shock dynamics and of the particle transport downstream of the shock, which allows us to compute the non-thermal emission from the remnant at any given age. We do this in 3D, in order to generate projected maps that can be compared with observations. We observe that completely different recipes for the magnetic field can lead to sim...

  12. Study of the initiation and the propagation of cracks under 3D thermal cyclic loading; Etude de l'amorcage et de la propagation des fissures sous chargement thermique cyclique 3D

    Energy Technology Data Exchange (ETDEWEB)

    Ancelet, O

    2005-07-01

    The incident which has occurred on the Civaux power plant has shown the noxiousness of thermal loading and the difficulty to take it into account at design level. The objective of this report is to study the initiation and the propagation of crack under thermal loading. In this aim the CEA has developed a new experiment named FAT3D. The various experiments carried out showed the harmfulness of a thermal loading, which makes it possible to rapidly initiate a network of cracks and to propagate one (or some) cracks through the totally thickness of the component under certain conditions. These experimental results associated with a mechanical analysis put at fault the usual criteria of damage based on the variations of the equivalent strain. In addition, the study of the propagation stage shows the importance of the plasticity which, in the case of a thermal loading, slows down the propagation of the crack. (author)

  13. 3D FIESTA联合3D TOF MRA对三叉神经血管压迫的诊断价值%Diagnostic value of MRI 3D FIESTA combined with 3D TOF MRA sequence in evaluation of the trigeminal neurovas-cular compression

    Institute of Scientific and Technical Information of China (English)

    朱敏; 周小飞; 李平

    2015-01-01

    目的:探讨MRI 3D循环相位稳态采集快速成像(FIESTA)序列联合3D TOF MRA序列对三叉神经血管压迫的诊断价值。方法:选取以原发性三叉神经痛就诊的患者25例,均行3D FIESTA和3D TOF MRA。由2名有经验的影像诊断医师在不知道临床症状的情况下对图像进行观察,分析2种序列中三叉神经和邻近血管的走行关系,以评价2种序列联合显示神经血管压迫与临床症状的相关性。结果:20例行手术治疗,与手术结果对照,MRI对血管压迫诊断的阳性符合率为78.9%(15/19),另4例为假阳性(21.1%,4/19);1例术前MRI诊断未见明确神经血管压迫者术中得到证实。5例术前MRI诊断无神经血管压迫的患者未行手术治疗。结论:MRI 3D FIESTA联合3D TOF MRA可清晰显示三叉神经的血管压迫情况,且与临床症状具较好相关性,可帮助临床医师进行术前评估。%Objective:To investigate the value of MRI 3D fast imaging employing steady-state (3D FIESTA) sequence combined with 3D time of flight magnetic resonance angiography (3D TOF MRA) in diagnosis of trigeminal neurovascular compression. Methods:25 cases of primary trigeminal neuralgia patients were examined by MRI (including 3D FIESTA and 3D TOF MRA). The images were reviewed by two experienced radiologists. The spatial relationships between the trigeminal nerve and adjacent vessels were overviewed,in order to evaluate the relevance between neurovascular compression and clinical symptoms. Results:20 cases were received microvacular decompression surgery. The presence of vascular compression were confirmed in 15 cases , with the positive coincidence rate of 78.9% (15/19),another 4 cases of false positive (21.1%,4/19). While the remain 1 case with diagnosis of no neurovascular compression was proved by surgery. 5 cases with preoperative MRI diagnosis of no neu-rovascular compression did not receive operation treatment. Conclusions

  14. Exploring single-molecule interactions through 3D optical trapping and tracking: From thermal noise to protein refolding

    Science.gov (United States)

    Wong, Wesley Philip

    The focus of this thesis is the development and application of a novel technique for investigating the structure and dynamics of weak interactions between and within single-molecules. This approach is designed to explore unusual features in bi-directional transitions near equilibrium. The basic idea is to infer molecular events by observing changes in the three-dimensional Brownian fluctuations of a functionalized microsphere held weakly near a reactive substrate. Experimentally, I have developed a unique optical tweezers system that combines an interference technique for accurate 3D tracking (˜1 nm vertically, and ˜2-3 nm laterally) with a continuous autofocus system which stabilizes the trap height to within 1-2 mn over hours. A number of different physical and biological systems were investigated with this instrument. Data interpretation was assisted by a multi-scale Brownian Dynamics simulation that I have developed. I have explored the 3D signatures of different molecular tethers, distinguishing between single and multiple attachments, as well as between stiff and soft linkages. As well, I have developed a technique for measuring the force-dependent compliance of molecular tethers from thermal noise fluctuations and demonstrated this with a short ssDNA oligomer. Another practical approach that I have developed for extracting information from fluctuation measurements is Inverse Brownian Dynamics, which yields the underlying potential of mean force and position dependent diffusion coefficient from the Brownian motion of a particle. I have also developed a new force calibration method that takes into account video motion blur, and that uses this information to measure bead dynamics. Perhaps most significantly, I have trade the first direct observations of the refolding of spectrin repeats under mechanical force, and investigated the force-dependent kinetics of this transition.

  15. A hybrid radial basis function-pseudospectral method for thermal convection in a 3-D spherical shell

    KAUST Repository

    Wright, G. B.

    2010-07-01

    A novel hybrid spectral method that combines radial basis function (RBF) and Chebyshev pseudospectral methods in a "2 + 1" approach is presented for numerically simulating thermal convection in a 3-D spherical shell. This is the first study to apply RBFs to a full 3-D physical model in spherical geometry. In addition to being spectrally accurate, RBFs are not defined in terms of any surface-based coordinate system such as spherical coordinates. As a result, when used in the lateral directions, as in this study, they completely circumvent the pole issue with the further advantage that nodes can be "scattered" over the surface of a sphere. In the radial direction, Chebyshev polynomials are used, which are also spectrally accurate and provide the necessary clustering near the boundaries to resolve boundary layers. Applications of this new hybrid methodology are given to the problem of convection in the Earth\\'s mantle, which is modeled by a Boussinesq fluid at infinite Prandtl number. To see whether this numerical technique warrants further investigation, the study limits itself to an isoviscous mantle. Benchmark comparisons are presented with other currently used mantle convection codes for Rayleigh number (Ra) 7 × 103 and 105. Results from a Ra = 106 simulation are also given. The algorithmic simplicity of the code (mostly due to RBFs) allows it to be written in less than 400 lines of MATLAB and run on a single workstation. We find that our method is very competitive with those currently used in the literature. Copyright 2010 by the American Geophysical Union.

  16. Evaluation of 3D metrology potential using a multiple detector CDSEM

    Science.gov (United States)

    Hakii, Hidemitsu; Yonekura, Isao; Nishiyama, Yasushi; Tanaka, Keishi; Komoto, Kenji; Murakawa, Tsutomu; Hiroyama, Mitsuo; Shida, Soichi; Kuribara, Masayuki; Iwai, Toshimichi; Matsumoto, Jun; Nakamura, Takayuki

    2012-06-01

    As feature sizes of semiconductor device structures have continuously decreased, needs for metrology tools with high precision and excellent linearity over actual pattern sizes have been growing. And it has become important to measure not only two-dimensional (2D) but also three-dimensional (3D) shapes of patterns at 22 nm node and beyond. To meet requirements for 3D metrology capabilities, various pattern metrology tools have been developed. Among those, we assume that CDSEM metrology is the most qualified candidate in the light of its non-destructive, high throughput measurement capabilities that are expected to be extended to the much-awaited 3D metrology technology. On the basis of this supposition, we have developed the 3D metrology system, in which side wall angles and heights of photomask patterns can be measured with high accuracy through analyzing CDSEM images generated by multi-channel detectors. In this paper, we will discuss our attempts to measure 3D shapes of defect patterns on a photomask by using Advantest's "Multi Vision Metrology SEM" E3630 (MVM-SEM' E3630).

  17. Solar Thermal Concept Evaluation

    Science.gov (United States)

    Hawk, Clark W.; Bonometti, Joseph A.

    1995-01-01

    Concentrated solar thermal energy can be utilized in a variety of high temperature applications for both terrestrial and space environments. In each application, knowledge of the collector and absorber's heat exchange interaction is required. To understand this coupled mechanism, various concentrator types and geometries, as well as, their relationship to the physical absorber mechanics were investigated. To conduct experimental tests various parts of a 5,000 watt, thermal concentrator, facility were made and evaluated. This was in anticipation at a larger NASA facility proposed for construction. Although much of the work centered on solar thermal propulsion for an upper stage (less than one pound thrust range), the information generated and the facility's capabilities are applicable to material processing, power generation and similar uses. The numerical calculations used to design the laboratory mirror and the procedure for evaluating other solar collectors are presented here. The mirror design is based on a hexagonal faceted system, which uses a spherical approximation to the parabolic surface. The work began with a few two dimensional estimates and continued with a full, three dimensional, numerical algorithm written in FORTRAN code. This was compared to a full geometry, ray trace program, BEAM 4, which optimizes the curvatures, based on purely optical considerations. Founded on numerical results, the characteristics of a faceted concentrator were construed. The numerical methodologies themselves were evaluated and categorized. As a result, the three-dimensional FORTRAN code was the method chosen to construct the mirrors, due to its overall accuracy and superior results to the ray trace program. This information is being used to fabricate and subsequently, laser map the actual mirror surfaces. Evaluation of concentrator mirrors, thermal applications and scaling the results of the 10 foot diameter mirror to a much larger concentrator, were studied. Evaluations

  18. Occupant thermal comfort evaluation

    Science.gov (United States)

    Ghiardi, Gena L.

    1999-03-01

    Throughout the automotive industry there has been an increasing concern and focus on the thermal comfort of occupants. Manufacturers are continuously striving to improve heating and air conditioning performance to comply with expanding customer needs. To optimize these systems, the technology to acquire data must also be enhanced. In this evaluation, the standard use of isolated thermocouple location technology is compared to utilizing infrared thermal vision in an air conditioning performance assessment. Infrared data on an actual occupant is correlated to breath and air conditioning output temperatures measured by positioned thermocouples. The use of infrared thermal vision highlights various areas of comfort and discomfort experienced by the occupant. The evaluation involves utilizing an infrared thermal vision camera to film an occupant in the vehicle as the following test procedure is run. The vehicle is soaked in full sun load until the interior temperature reaches a minimum of 150 degrees F (65.6 degrees Celsius). The occupant enters the vehicle and takes an initial temperature reading. The air conditioning is turned on to full cold, full fan speed, and recirculation mode. While being filmed, the driver drives for sixty minutes at 30 miles per hour (48.3 kph). The thermocouples acquire data in one minute intervals while the infrared camera films the cooling process of the occupant.

  19. Evaluation of radiotherapy setup accuracy for head and neck cancer using a 3-D surface imaging system

    Science.gov (United States)

    Cho, H.-L.; Park, E.-T.; Kim, J.-Y.; Kwak, K.-S.; Kim, C.-J.; Ahn, K.-J.; Suh, T.-S.; Lee, Y.-K.; Kim, S.-W.; Kim, J.-K.; Lim, S.; Choi, Y.-M.; Park, S.-K.

    2013-11-01

    The purpose of this study was to measure the accuracy of a three-dimensional surface imaging system (3-D SIS) in comparison to a 3-laser system by analyzing the setup errors obtained from a RANDO Phantom and head and neck cancer patients. The 3-D SIS used for the evaluation of the setup errors was a C-RAD Sentinel. In the phantom study, the OBI setup errors without the thermoplastic mask of the 3-laser system vs. the 3-D SIS were measured. Furthermore, the setup errors with the thermoplastic mask of the 3-laser system vs. the 3-D SIS were measured. After comparison of the CBCT, setup correction about 1 mm was performed in a few cases. The probability of the error without the thermoplastic mask exceeding 1 mm in the 3-laser system vs. the 3-D SIS was 75.00% vs. 35.00% on the X-axis, 80.00% vs. 40.00% on the Y-axis, and 80.00% vs. 65.00% on the Z-axis. Moreover, the probability of the error with the thermoplastic mask exceeding 1 mm in the 3-laser system vs. the 3-D SIS was 70.00% vs. 15.00% on the X-axis, 75.00% vs. 25.00% on the Y-axis, and 70.00% vs. 35.00% on the Z-axis. These results showed that the 3-D SIS has a lower probability of setup error than the 3-laser system for the phantom. For the patients, the setup errors of the 3-laser system vs. the 3-D SIS were measured. The probability of the error exceeding more than 1 mm in the 3-laser system vs. the 3-D SIS was shown to be 81.82% vs. 36.36% on the X-axis, 81.82% vs. 45.45% on the Y-axis, and 86.36% vs. 72.73% on the Z-axis. As a result, the 3-D SIS also exhibited a lower probability of setup error for the cancer patients. Therefore, this study confirmed that the 3-D SIS is a promising method for setup verification.

  20. Evaluation of the durability of 3D printed keys produced by computational processing of image data

    Science.gov (United States)

    Straub, Jeremy; Kerlin, Scott

    2016-05-01

    Possession of a working 3D printed key can, for most practical purposes, convince observers that an illicit attempt to gain premises access is authorized. This paper seeks to assess three things. First, work has been performed to determine how easily the data for making models of keys can be obtained through manual measurement. It then presents work done to create a model of the key and determine how easy key modeling could be (particularly after a first key of a given key `blank' has been made). Finally, it seeks to assess the durability of the keys produced using 3D printing.

  1. Thermal evaluation of buildings

    OpenAIRE

    Barajas, Luís M; Roset Calzada, Jaime; La Ferla, Giuseppe

    2015-01-01

    To COST ACTION TU 1104 "Smart Energy Regions" Prof. Aleksandra Djukic and Prof. Aleksandra Krstic-Furundzic of the Faculty of Architecture of the University of Belgrade, Serbia, that gave us the opportunity of be part of the training school imparted from Monday 20th to Thursday 23rd April 2015, where we can teach the topic. The convenience of the use of environmental building evaluation tools, to know design conditions and thermal behavior, by using bioclimatic strategies fo...

  2. Using Geometry-Based Metrics as Part of Fitness-for-Purpose Evaluations of 3D City Models

    Science.gov (United States)

    Wong, K.; Ellul, C.

    2016-10-01

    Three-dimensional geospatial information is being increasingly used in a range of tasks beyond visualisation. 3D datasets, however, are often being produced without exact specifications and at mixed levels of geometric complexity. This leads to variations within the models' geometric and semantic complexity as well as the degree of deviation from the corresponding real world objects. Existing descriptors and measures of 3D data such as CityGML's level of detail are perhaps only partially sufficient in communicating data quality and fitness-for-purpose. This study investigates whether alternative, automated, geometry-based metrics describing the variation of complexity within 3D datasets could provide additional relevant information as part of a process of fitness-for-purpose evaluation. The metrics include: mean vertex/edge/face counts per building; vertex/face ratio; minimum 2D footprint area and; minimum feature length. Each metric was tested on six 3D city models from international locations. The results show that geometry-based metrics can provide additional information on 3D city models as part of fitness-for-purpose evaluations. The metrics, while they cannot be used in isolation, may provide a complement to enhance existing data descriptors if backed up with local knowledge, where possible.

  3. Detailed Evaluation of Five 3D Speckle Tracking Algorithms Using Synthetic Echocardiographic Recordings.

    Science.gov (United States)

    Alessandrini, Martino; Heyde, Brecht; Queiros, Sandro; Cygan, Szymon; Zontak, Maria; Somphone, Oudom; Bernard, Olivier; Sermesant, Maxime; Delingette, Herve; Barbosa, Daniel; De Craene, Mathieu; ODonnell, Matthew; Dhooge, Jan

    2016-08-01

    A plethora of techniques for cardiac deformation imaging with 3D ultrasound, typically referred to as 3D speckle tracking techniques, are available from academia and industry. Although the benefits of single methods over alternative ones have been reported in separate publications, the intrinsic differences in the data and definitions used makes it hard to compare the relative performance of different solutions. To address this issue, we have recently proposed a framework to simulate realistic 3D echocardiographic recordings and used it to generate a common set of ground-truth data for 3D speckle tracking algorithms, which was made available online. The aim of this study was therefore to use the newly developed database to contrast non-commercial speckle tracking solutions from research groups with leading expertise in the field. The five techniques involved cover the most representative families of existing approaches, namely block-matching, radio-frequency tracking, optical flow and elastic image registration. The techniques were contrasted in terms of tracking and strain accuracy. The feasibility of the obtained strain measurements to diagnose pathology was also tested for ischemia and dyssynchrony. PMID:26960220

  4. The development and evaluation of RF TSV for 3D IPD applications

    NARCIS (Netherlands)

    Ebefors, T.; Fredlund, J.; Perttu, D.; Dijk, R. van; Cifola, L.; Kaunisto, M.; Rantakari, P.; Vähä-Heikkilä, T.

    2013-01-01

    In this paper, Silex Microsystems, the world's largest Pure-Play MEMS foundry, together with partners TNO and VTT, present our recent advancements in RF through silicon Vias (TSV) for 3D integrated passive devices (IPD) applications, achieved in conjunction with the European consortium EPAMO. A nove

  5. Evaluation of Gastric Volumes: Comparison of 3-D Ultrasound and Magnetic Resonance Imaging.

    Science.gov (United States)

    Buisman, Wijnand J; Mauritz, Femke A; Westerhuis, Wouter E; Gilja, Odd Helge; van der Zee, David C; van Herwaarden-Lindeboom, Maud Y A

    2016-07-01

    To investigate gastric accommodation, accurate measurements of gastric volumes are necessary. An excellent technique to measure gastric volumes is dynamic magnetic resonance imaging (MRI). Unfortunately, dynamic MRI is expensive and not always available. A new 3-D ultrasound (US) method using a matrix transducer was developed to measure gastric volumes. In this prospective study, 14 healthy volunteers underwent a dynamic MRI and a 3-D US. Gastric volumes were calculated with intra-gastric liquid content and total gastric volume. Mean postprandial liquid gastric content was 397 ± 96.5 mL. Mean volume difference was 1.0 mL with limits of agreement of -8.9 to 10.9 mL. When gastric air was taken into account, mean total gastric volume was 540 ± 115.4 mL SD. Mean volume difference was 2.3 mL with limits of agreement of -21.1 to 26.4 mL. The matrix 3-D US showed excellent agreement with dynamic MRI. Therefore matrix 3-D US is a reliable alternative to measure gastric volumes. PMID:27067418

  6. Evaluation and Performance Analysis of 3D Printing Technique for Ka-Band Antenna Production

    DEFF Research Database (Denmark)

    Armendariz, Unai; Rommel, Simon; Rodríguez Páez, Juan Sebastián;

    2016-01-01

    This paper presents the design and fabrication of 3D printed WR-28 waveguide horn antennas operating in the Ka-band frequency range between 26.5GHz and 40GHz. Three antennas are fabricated from polylactide acid filaments in conductive and non-conductive variants; the latter is covered...

  7. Evaluation of 2D and 3D glove input applied to medical image analysis

    NARCIS (Netherlands)

    E.V. Zudilova-Seinstra; P.J.H. de Koning; A. Suinesiaputra; B.W. van Schooten; R.J. van der Geest; J.H.C. Reiber; P.M.A. Sloot

    2010-01-01

    We describe a series of experiments that compared 2D/3D input methods for selection and positioning tasks related to medical image analysis. For our study, we chose a switchable P5 Glove Controller, which can be used to provide both 2DOF and 6DOF input control. Our results suggest that for both task

  8. Electrical impedance tomography in 3D using two electrode planes: characterization and evaluation.

    Science.gov (United States)

    Wagenaar, Justin; Adler, Andy

    2016-06-01

    Electrical impedance tomography (EIT) uses body surface electrical stimulation and measurements to create conductivity images; it shows promise as a non-invasive technology to monitor the distribution of lung ventilation. Most applications of EIT have placed electrodes in a 2D ring around the thorax, and thus produced 2D cross-sectional images. These images are unable to distinguish out-of-plane contributions, or to image volumetric effects. Volumetric EIT can be calculated using multiple electrode planes and a 3D reconstruction algorithm. However, while 3D reconstruction algorithms are available, little has been done to understand the performance of 3D EIT in terms of the measurement configurations available. The goal of this paper is to characterize the phantom and in vivo performance of 3D EIT with two electrode planes. First, phantom measurements are used to measure the reconstruction characteristics of seven stimulation and measurement configurations. Measurements were then performed on eight healthy volunteers as a function of body posture, postures, and with various electrode configurations. Phantom results indicate that 3D EIT using two rings of electrodes provides reasonable resolution in the electrode plane but low vertical resolution. For volunteers, functional EIT images are created from inhalation curve features to analyze the effect of posture (standing, sitting, supine and decline) on regional lung behaviour. An ability to detect vertical changes in lung volume distribution was shown for two electrode configurations. Based on tank and volunteer results, we recommend the use of the 'square' stimulation and measurement pattern for two electrode plane EIT.

  9. Atmospheric correction of thermal-infrared imagery of the 3-D urban environment acquired in oblique viewing geometry

    Directory of Open Access Journals (Sweden)

    F. Meier

    2010-12-01

    Full Text Available This research quantifies and discusses atmospheric effects that alter the radiance observed by a ground-based thermal-infrared (TIR camera mounted on top of a high-rise building in the city of Berlin, Germany. The study shows that atmospheric correction of ground-based TIR imagery of the three-dimensional (3-D urban environment acquired in oblique viewing geometry has to account for spatial variability of line-of-sight (LOS geometry. We present an atmospheric correction procedure that uses these spatially distributed LOS geometry parameters, the radiative transfer model MODTRAN 5.2 and atmospheric profile data derived from meteorological measurements in the field of view (FOV of the TIR camera. The magnitude of atmospheric effects varies during the analysed 24-hourly period (8 August 2009 and is particularly notable for surfaces showing a strong surface-to-air temperature difference. The differences between uncorrected and corrected TIR imagery reach up to 7.7 K at 12:00. Atmospheric effects are biased up to 4.3 K at 12:00 and up to 0.6 K at 24:00, if non-spatially distributed LOS parameters are used.

  10. Development and Evaluation of 2-D and 3-D Exocentric Synthetic Vision Navigation Display Concepts for Commercial Aircraft

    Science.gov (United States)

    Prinzel, Lawrence J., III; Kramer, Lynda J.; Arthur, J. J., III; Bailey, Randall E.; Sweeters, Jason L.

    2005-01-01

    NASA's Synthetic Vision Systems (SVS) project is developing technologies with practical applications that will help to eliminate low visibility conditions as a causal factor to civil aircraft accidents while replicating the operational benefits of clear day flight operations, regardless of the actual outside visibility condition. The paper describes experimental evaluation of a multi-mode 3-D exocentric synthetic vision navigation display concept for commercial aircraft. Experimental results evinced the situation awareness benefits of 2-D and 3-D exocentric synthetic vision displays over traditional 2-D co-planar navigation and vertical situation displays. Conclusions and future research directions are discussed.

  11. Evaluation of dosimetric misrepresentations from 3D conventional planning of liver SBRT using 4D deformable dose integration.

    Science.gov (United States)

    Yeo, Unjin A; Taylor, Michael L; Supple, Jeremy R; Siva, Shankar; Kron, Tomas; Pham, Daniel; Franich, Rick D

    2014-01-01

    The purpose of this study is to evaluate dosimetric errors in 3D conventional plan- ning of stereotactic body radiotherapy (SBRT) by using a 4D deformable image registration (DIR)-based dose-warping and integration technique. Respiratory- correlated 4D CT image sets with 10 phases were acquired for four consecutive patients with five liver tumors. Average intensity projection (AIP) images were used to generate 3D conventional plans of SBRT. Quasi-4D path-integrated dose accumulation was performed over all 10 phases using dose-warping techniques based on DIR. This result was compared to the conventional plan in order to evalu- ate the appropriateness of 3D (static) dose calculations. In addition, we consider whether organ dose metrics derived from contours defined on the average intensity projection (AIP), or on a reference phase, provide the better approximation of the 4D values. The impact of using fewer (3D planning approach overestimated doses to targets by 1.4% to 8.7% (mean 4.2%) and underestimated dose to normal liver by up to 8% (mean -5.5%; range -2.3% to -8.0%), compared to the 4D methodology. The homogeneity of the dose distribution was overestimated when using conventional 3D calculations by up to 24%. OAR doses estimated by 3D planning were, on average, within 10% of the 4D calculations; however, differences of up to 100% were observed. Four-dimensional dose calculation using 3 phases gave a reasonable approximation of that calculated from the full 10 phases for all patients, which is potentially useful from a workload perspective. 4D evaluation showed that conventional 3D planning on an AIP can significantly overestimate target dose (ITV and GTV+5mm), underestimate normal liver dose, and overestimate dose homogeneity. Implementing nonadaptive quasi- 4D dose calculation can highlight the potential limitation of 3D conventional SBRT planning and the resultant misrepresentations of dose in some regions affected by motion and deformation. Where the 4D

  12. Clinical evaluation of 3D/3D MRI-CBCT automatching on brain tumors for online patient setup verification - A step towards MRI-based treatment planning

    DEFF Research Database (Denmark)

    Buhl, Sune K.; Duun-Christensen, Anne Katrine; Kristensen, Brian H.;

    2010-01-01

    Background. Magnetic Resonance Imaging (MRI) is often used in modern day radiotherapy (RT) due to superior soft tissue contrast. However, treatment planning based solely on MRI is restricted due to e. g. the limitations of conducting online patient setup verification using MRI as reference....... In this study 3D/3D MRI-Cone Beam CT (CBCT) automatching for online patient setup verification was investigated. Material and methods. Initially, a multi-modality phantom was constructed and used for a quantitative comparison of CT-CBCT and MRI-CBCT automatching. Following the phantom experiment three patients...... undergoing postoperative radiotherapy for malignant brain tumors received a weekly CBCT. In total 18 scans was matched with both CT and MRI as reference. The CBCT scans were acquired using a Clinac iX 2300 linear accelerator (Varian Medical Systems) with an On-Board Imager (OBI). Results. For the phantom...

  13. Clinical evaluation of 3D/3D MRI-CBCT automatching on brain tumors for online patient setup verification - A step towards MRI-based treatment planning

    DEFF Research Database (Denmark)

    Buhl, S.K.; Duun-Christensen, Anne Katrine; Kristensen, B.H.;

    2010-01-01

    undergoing postoperative radiotherapy for malignant brain tumors received a weekly CBCT. In total 18 scans was matched with both CT and MRI as reference. The CBCT scans were acquired using a Clinac iX 2300 linear accelerator (Varian Medical Systems) with an On-Board Imager (OBI). Results. For the phantom......Background. Magnetic Resonance Imaging (MRI) is often used in modern day radiotherapy (RT) due to superior soft tissue contrast. However, treatment planning based solely on MRI is restricted due to e. g. the limitations of conducting online patient setup verification using MRI as reference....... In this study 3D/3D MRI-Cone Beam CT (CBCT) automatching for online patient setup verification was investigated. Material and methods. Initially, a multi-modality phantom was constructed and used for a quantitative comparison of CT-CBCT and MRI-CBCT automatching. Following the phantom experiment three patients...

  14. Building and Evaluating a 3D Scanning System for Measurementsand Estimation of Antennas and Propagation Channels

    OpenAIRE

    Aagaard Fransson, Erik Johannes; Wall-Horgen, Tobias

    2012-01-01

    Wireless communications rely, among other things, on theunderstanding of the properties of the radio propagationchannel, the antennas and their interplay. Adequate measurementsare required to verify theoretical models and togain knowledge of the channel behavior and antenna performance.As a result of this master thesis we built a 3D fieldscanner measurement system to predict multipath propagationand to measure antenna characteristics. The 3Dscanner allows measuring a signal at the point of in...

  15. Hausdorff Distance evaluation of orthodontic accessories' streaking artifacts in 3D model superimposition

    Directory of Open Access Journals (Sweden)

    José Rino Neto

    2012-10-01

    Full Text Available The aim of this study was to determine whether image artifacts caused by orthodontic metal accessories interfere with the accuracy of 3D CBCT model superimposition. A human dry skull was subjected three times to a CBCT scan: at first without orthodontic brackets (T1, then with stainless steel brackets bonded without (T2 and with orthodontic arch wires (T3 inserted into the brackets' slots. The registration of image surfaces and the superimposition of 3D models were performed. Within-subject surface distances between T1-T2, T1-T3 and T2-T3 were computed and calculated for comparison among the three data sets. The minimum and maximum Hausdorff Distance units (HDu computed between the corresponding data points of the T1 and T2 CBCT 3D surface images were 0.000000 and 0.049280 HDu, respectively, and the mean distance was 0.002497 HDu. The minimum and maximum Hausdorff Distances between T1 and T3 were 0.000000 and 0.047440 HDu, respectively, with a mean distance of 0.002585 HDu. In the comparison between T2 and T3, the minimum, maximum and mean Hausdorff Distances were 0.000000, 0.025616 and 0.000347 HDu, respectively. In the current study, the image artifacts caused by metal orthodontic accessories did not compromise the accuracy of the 3D model superimposition. Color-coded maps of overlaid structures complemented the computed Hausdorff Distances and demonstrated a precise fusion between the data sets.

  16. Development and validation of CONV-3D code for calculation of thermal and hydrodynamics of Fast Reactor at the Supercomputer

    International Nuclear Information System (INIS)

    In IBRAE 3D CFD modules (CONV code) for safety analysis of the operated Nuclear Power Plants (NPPs) are developed. These modules are based on the developed algorithms with small scheme diffusion, for which the discrete approximations are constructed with use of finite-volume methods and fully staggered grids. For solving of convection problem the regularized nonlinear monotonic operator-splitting scheme is developed. The Richardson iterative method with iterative Fast Fourier Transformation (FFT) solver for Laplace’s operator as preconditioner is applied for solving pressure equation. Such approach for solving of the elliptical equations with variable coefficients gives multiple acceleration in a comparison with a usual method of conjugate gradients. For modeling of 3D turbulent single-phase flows Quasi DNS approach is used. The CONV code is fully parallelized and highly effective at the high performance computers such as “Chebyshev”, “Lomonosov” (Moscow State University). The developed modules were validated on a series of the well known tests in a wide range of Rayleigh numbers from a range 106-1016 and Reynolds numbers from a range 103-105. The software has been applied to the analysis results of test LIVE-L1 (L1 is aimed at investigating the melt pool and crust behaviour during the stages of air circulation at the outer RPV surface with subsequent flooding of the lower head) and joint analyses on transient molten pool thermal hydraulics in the LIVE facility in the framework of ISTC project. Moreover CONV was validated successfully on a series of the experimental tests as: the blind test on simulation of flows in T-junction (OECD/NEA), ERCOFTAC experiment (world database on turbulent flows) natural convection in the closures under extremely high Rayleigh numbers. In all cases the good coincidence of numerical predictions with experimental data was reached, that specifies a possibility of application of the developed approach for a prediction of CFD

  17. 3D-TOF MRA与MRI联合应用在颅内动脉瘤的诊断价值%Evaluation of 3D-TOF MRA Combined with MRI in the Diagnosis of Intracranial Aneurysms

    Institute of Scientific and Technical Information of China (English)

    沈文东; 曹志宏; 吴立伟; 单海荣

    2012-01-01

    Objective To assess the Evaluation of 3D-TOF MRA combined with MRI in the diagnosis of intracranial aneurysms. Methods 18 cases of intracranial aneurysms were confirmed by digital subtraction angiography(DSA),To retrospectively analyze the MRA and MRI information. MRA was done with 3D-TOF sequences and MRI was performed with SET1 and T2 weighted suquences. Results 21 aneurysms were proved by in 18 cases, 19 aneurysms were found on 3D-TOF MRA. 17 aneurysms were found on MRI. all aneurysms were found on 3D-TOF MRA combined with MRi. Conclusion 3D-TOF MRA combined with MRI may improve the diagnostic accuracy.%目的 探讨3D-TOF MRA与MRI联合应用在颅内动脉瘤中的诊断价值.方法 选择经DSA证实为颅内动脉瘤且资料齐全的18例患者,回顾性分析其MRA、MRI资料.MRA采用三维时间飞跃法(3D-TOF),MRI采用SE T1WI、T2WI成像.结果 18例患者共计21个病灶,3D-TOF MRA显示19个病灶,MRI显示17个病灶,3D-TOF MRA联合MRI则全部显示病灶并确诊.结论 3D-TOF MRA与MRI联合应用可极大地提高颅内动脉瘤的发现率及确诊率.

  18. A global 3-D CTM evaluation of black carbon in the Tibetan Plateau

    Science.gov (United States)

    He, C.; Li, Q. B.; Liou, K. N.; Zhang, J.; Qi, L.; Mao, Y.; Gao, M.; Lu, Z.; Streets, D. G.; Zhang, Q.; Sarin, M. M.; Ram, K.

    2014-07-01

    We systematically evaluate the black carbon (BC) simulations for 2006 over the Tibetan Plateau by a global 3-D chemical transport model (CTM) (GEOS-Chem) driven by GEOS-5 assimilated meteorological fields, using in situ measurements of BC in surface air, BC in snow, and BC absorption aerosol optical depth (AAOD). Using improved anthropogenic BC emission inventories for Asia that account for rapid technology renewal and energy consumption growth (Zhang et al., 2009; Lu et al., 2011) and improved global biomass burning emission inventories that account for small fires (van der Werf et al., 2010; Randerson et al., 2012), we find that model results of both BC in surface air and in snow are statistically in good agreement with observations (biases factor of 2 of the observations at remote sites. Part of the discrepancy is explained by the deficiencies of the meteorological fields over the complex Tibetan terrain. We find that BC concentrations in snow computed from modeled BC deposition and GEOS-5 precipitation are spatiotemporally consistent with observations (r = 0.85). The computed BC concentrations in snow are a factor of 2-4 higher than the observations at several Himalayan sites because of excessive BC deposition. The BC concentrations in snow are biased low by a factor of 2 in the central plateau, which we attribute to the absence of snow aging in the CTM and strong local emissions unaccounted for in the emission inventories. Modeled BC AAOD is more than a factor of 2 lower than observations at most sites, particularly to the northwest of the plateau and along the southern slopes of the Himalayas in winter and spring, which is attributable in large part to underestimated emissions and the assumption of external mixing of BC aerosols in the model. We find that assuming a 50% increase of BC absorption associated with internal mixing reduces the bias in modeled BC AAOD by 57% in the Indo-Gangetic Plain and the northeastern plateau and to the northeast of the plateau

  19. In vivo 3D neuroanatomical evaluation of periprostatic nerve plexus with 3T-MR Diffusion Tensor Imaging

    International Nuclear Information System (INIS)

    Objectives: To evaluate if Diffusion Tensor Imaging technique (DTI) can improve the visualization of periprostatic nerve fibers describing the location and distribution of entire neurovascular plexus around the prostate in patients who are candidates for prostatectomy. Materials and methods: Magnetic Resonance Imaging (MRI), including a 2D T2-weighted FSE sequence in 3 planes, 3D T2-weighted and DTI using 16 gradient directions and b = 0 and 1000, was performed on 36 patients. Three out of 36 patients were excluded from the analysis due to poor image quality (blurring N = 2, artifact N = 1). The study was approved by local ethics committee and all patients gave an informed consent. Images were evaluated by two radiologists with different experience in MRI. DTI images were analyzed qualitatively using dedicated software. Also 2D and 3D T2 images were independently considered. Results: 3D-DTI allowed description of the entire plexus of the periprostatic nerve fibers in all directions, while 2D and 3D T2 morphological sequences depicted part of the fibers, in a plane by plane analysis of fiber courses. DTI demonstrated in all patients the dispersion of nerve fibers around the prostate on both sides including the significant percentage present in the anterior and anterolateral sectors. Conclusions: DTI offers optimal representation of the widely distributed periprostatic plexus. If validated, it may help guide nerve-sparing radical prostatectomy

  20. Evaluation of the use of 3D printing and imaging to create working replica keys

    Science.gov (United States)

    Straub, Jeremy; Kerlin, Scott

    2016-06-01

    This paper considers the efficacy of 3D scanning and printing technologies to produce duplicate keys. Duplication of keys, based on remote-sensed data represents a significant security threat, as it removes pathways to determining who illicitly gained access to a secured premises. Key to understanding the threat posed is the characterization of the easiness of gaining the required data for key production and an understanding of how well keys produced under this method work. The results of an experiment to characterize this are discussed and generalized to different key types. The effect of alternate sources of data on imaging requirements is considered.

  1. Entwicklung und Evaluation einer Kalibrierungsmethode für 3D-Ultraschall

    Science.gov (United States)

    Bergmeir, Christoph; Seitel, Mathias; Frank, Christian; de Simone, Raffaele; Meinzer, Hans-Peter; Wolf, Ivo

    Wir stellen eine Methode zur Kalibrierung einer 3D-Ultraschallsonde vor. Für Anwendungen in der minimalinvasiven Chirurgie wird die Ultraschallsonde mit einem Trackingsystem verbunden, um dem Aufnahmevolumen eine definierte räumliche Lage zu geben. Die Kalibrierung bringt die Koordinatensysteme des Trackingsystems und des Ultraschallbildes zur Deckung. Hierzu wird ein bekanntes Objekt, das Phantom, aufgenommen und im Ultraschallbild lokalisiert. Die Kalibrierungstransformation wird dann durch ein Verfahren der Hand-Auge-Kalibrierung errechnet. Ein oft übliches Anbringen zusätzlicher Trackingssensoren am Phantom ist damit nicht nötig, was die Kalibrierungsprozedur vereinfacht.

  2. CT virtual endoscopy and 3D stereoscopic visualisation in the evaluation of coronary stenting.

    Science.gov (United States)

    Sun, Z; Lawrence-Brown

    2009-10-01

    The aim of this case report is to present the additional value provided by CT virtual endoscopy and 3D stereoscopic visualisation when compared with 2D visualisations in the assessment of coronary stenting. A 64-year old patient was treated with left coronary stenting 8 years ago and recently followed up with multidetector row CT angiography. An in-stent restenosis of the left coronary artery was suspected based on 2D axial and multiplanar reformatted images. 3D virtual endoscopy was generated to demonstrate the smooth intraluminal surface of coronary artery wall, and there was no evidence of restenosis or intraluminal irregularity. Virtual fly-through of the coronary artery was produced to examine the entire length of the coronary artery with the aim of demonstrating the intraluminal changes following placement of the coronary stent. In addition, stereoscopic views were generated to show the relationship between coronary artery branches and the coronary stent. In comparison with traditional 2D visualisations, virtual endoscopy was useful for assessment of the intraluminal appearance of the coronary artery wall following coronary stent implantation, while stereoscopic visualisation improved observers' understanding of the complex cardiac structures. Thus, both methods could be used as a complementary tool in cardiac imaging.

  3. Evaluation of 3D-human skin equivalents for assessment of human dermal absorption of some brominated flame retardants.

    Science.gov (United States)

    Abdallah, Mohamed Abou-Elwafa; Pawar, Gopal; Harrad, Stuart

    2015-11-01

    Ethical and technical difficulties inherent to studies in human tissues are impeding assessment of the dermal bioavailability of brominated flame retardants (BFRs). This is further complicated by increasing restrictions on the use of animals in toxicity testing, and the uncertainties associated with extrapolating data from animal studies to humans due to inter-species variations. To overcome these difficulties, we evaluate 3D-human skin equivalents (3D-HSE) as a novel in vitro alternative to human and animal testing for assessment of dermal absorption of BFRs. The percutaneous penetration of hexabromocyclododecanes (HBCD) and tetrabromobisphenol-A (TBBP-A) through two commercially available 3D-HSE models was studied and compared to data obtained for human ex vivo skin according to a standard protocol. No statistically significant differences were observed between the results obtained using 3D-HSE and human ex vivo skin at two exposure levels. The absorbed dose was low (less than 7%) and was significantly correlated with log Kow of the tested BFR. Permeability coefficient values showed increasing dermal resistance to the penetration of γ-HBCD>β-HBCD>α-HBCD>TBBPA. The estimated long lag times (>30 min) suggests that frequent hand washing may reduce human exposure to HBCDs and TBBPA via dermal contact. PMID:26232142

  4. Evaluation of 3D-human skin equivalents for assessment of human dermal absorption of some brominated flame retardants.

    Science.gov (United States)

    Abdallah, Mohamed Abou-Elwafa; Pawar, Gopal; Harrad, Stuart

    2015-11-01

    Ethical and technical difficulties inherent to studies in human tissues are impeding assessment of the dermal bioavailability of brominated flame retardants (BFRs). This is further complicated by increasing restrictions on the use of animals in toxicity testing, and the uncertainties associated with extrapolating data from animal studies to humans due to inter-species variations. To overcome these difficulties, we evaluate 3D-human skin equivalents (3D-HSE) as a novel in vitro alternative to human and animal testing for assessment of dermal absorption of BFRs. The percutaneous penetration of hexabromocyclododecanes (HBCD) and tetrabromobisphenol-A (TBBP-A) through two commercially available 3D-HSE models was studied and compared to data obtained for human ex vivo skin according to a standard protocol. No statistically significant differences were observed between the results obtained using 3D-HSE and human ex vivo skin at two exposure levels. The absorbed dose was low (less than 7%) and was significantly correlated with log Kow of the tested BFR. Permeability coefficient values showed increasing dermal resistance to the penetration of γ-HBCD>β-HBCD>α-HBCD>TBBPA. The estimated long lag times (>30 min) suggests that frequent hand washing may reduce human exposure to HBCDs and TBBPA via dermal contact.

  5. Validation of a CFD code Star-CCM+ for liquid lead-bismuth eutectic thermal-hydraulics using TALL-3D experiment

    International Nuclear Information System (INIS)

    The engineering design, performance analysis and safety assessment of Generation IV heavy liquid metal cooled nuclear reactors calls for advanced and qualified numerical tools. These tools need to be qualified before used in decision making process. Computational Fluid Dynamics (CFD) codes provide detailed means for thermal-hydraulics analysis of pool-type nuclear reactors. This paper describes modeling of a forced to natural flow experiment in TALL-3D experimental facility using a commercial CFD code Star-CCM+. TALL-3D facility is 7 meters high LBE loop with two parallel hot legs and a cold leg. One of the hot legs accommodates the 3D test section, a cylindrical pool where the multi-dimensional flow conditions vary between thermal mixing and stratification depending on the mass flow rate and the power of the heater surrounding the pool. The pool outlet temperature which affects the natural convection flow rates in the system is governed by the flow structure in the pool. Therefore, in order to predict the dynamics of the TALL-3D facility it is crucial to resolve the flow inside the 3D test section. Specifically designed measurement instrumentation set-up provides steady state and transient data for calibration and validation of numerical models. The validity of the CFD model is assessed by comparing the computational results to experimental results. (author)

  6. Multimodal, 3D pathology-mimicking bladder phantom for evaluation of cystoscopic technologies (Conference Presentation)

    Science.gov (United States)

    Smith, Gennifer T.; Lurie, Kristen L.; Zlatev, Dimitar V.; Liao, Joseph C.; Ellerbee, Audrey K.

    2016-02-01

    Optical coherence tomography (OCT) and blue light cystoscopy (BLC) have shown significant potential as complementary technologies to traditional white light cystoscopy (WLC) for early bladder cancer detection. Three-dimensional (3D) organ-mimicking phantoms provide realistic imaging environments for testing new technology designs, the diagnostic potential of systems, and novel image processing algorithms prior to validation in real tissue. Importantly, the phantom should mimic features of healthy and diseased tissue as they appear under WLC, BLC, and OCT, which are sensitive to tissue color and structure, fluorescent contrast, and optical scattering of subsurface layers, respectively. We present a phantom posing the hollow shape of the bladder and fabricated using a combination of 3D-printing and spray-coating with Dragon Skin (DS) (Smooth-On Inc.), a highly elastic polymer to mimic the layered structure of the bladder. Optical scattering of DS was tuned by addition of titanium dioxide, resulting in scattering coefficients sufficient to cover the human bladder range (0.49 to 2.0 mm^-1). Mucosal vasculature and tissue coloration were mimicked with elastic cord and red dye, respectively. Urethral access was provided through a small hole excised from the base of the phantom. Inserted features of bladder pathology included altered tissue color (WLC), fluorescence emission (BLC), and variations in layered structure (OCT). The phantom surface and underlying material were assessed on the basis of elasticity, optical scattering, layer thicknesses, and qualitative image appearance. WLC, BLC, and OCT images of normal and cancerous features in the phantom qualitatively matched corresponding images from human bladders.

  7. Interaction with a 3D modeling tool through a gestural interface : An Evaluation of Effectiveness and Quality

    OpenAIRE

    Gustavsson, David

    2014-01-01

    Context. Gestural interfaces involves the ability of technology identifying and recognizing human body language and then interpret this into commands. This is usually used to ease our everyday life, but also to increase usability in for example mobile phones. Objectives. In this study the use of a gestural interface is evaluated as an interaction method to facilitate the introduction of new and novice users to 3D modeling tools. A gestural interface might reduce the modeling time without maki...

  8. Characterization of the 3D distribution of ozone and coarse aerosols in the Troposphere using IASI thermal infrared satellite observations

    Science.gov (United States)

    Cuesta, J.; Eremenko, M.; Dufour, G.; Hoepfner, M.; Orphal, J.

    2012-04-01

    Both tropospheric ozone and aerosols significantly affect air quality in megacities during pollution events. Moreover, living conditions may be seriously aggravated when such agglomerations are affected by wildfires (e.g. Russian fires over Moscow in 2010), which produce smoke and pollutant precursors, or even during dense desert dust outbreaks (e.g. recurrently over Beijing or Cairo). Moreover, since aerosols diffuse and absorb solar radiation, they have a direct impact on the photochemical production of tropospheric ozone. These interactions during extreme events of high aerosol loads are nowadays poorly known, even though they may significantly affect the tropospheric photochemical equilibrium. In order to address these issues, we have developed a new retrieval technique to jointly characterize the 3D distribution of both tropospheric ozone and coarse aerosols, using spaceborne observations of the infrared spectrometer IASI onboard MetOp-A satellite. Our methodology is based on the inversion of Earth radiance spectra in the atmospheric window from 8 to 12 μm measured by IASI and a «Tikhonov-Philipps»-type regularisation with constraints varying in altitude (as in [Eremenko et al., 2008, GRL; Dufour et al., 2010 ACP]) to simultaneously retrieve ozone profiles, aerosol optical depths at 10 μm and aerosol layer effective heights. Such joint retrieval prevents biases in the ozone profile retrieval during high aerosol load conditions. Aerosol retrievals using thermal infrared radiances mainly account for desert dust and the coarse fraction of biomass burning aerosols. We use radiances from 15 micro-windows within the 8-12 μm atmospheric window, which were carefully chosen (following [Worden et al., 2006 JGR]) for extracting the maximum information on aerosols and ozone and minimizing contamination by other species. We use the radiative transfer code KOPRA, including line-by-line calculations of gas absorption and single scattering for aerosols [Hoepfner et al

  9. Use of VAP3D software in the construction of pathological anthropomorphic phantoms for dosimetric evaluations; Uso do software VAP3D na construcao de fantomas antropomorficos patologicos para avaliacoes dosimetricas

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Lindeval Fernandes de [Universidade Federal de Pernambuco (DEM/UFPE), Recife, PE (Brazil). Dept. de Engenharia Mecanica; Vieira, Jose Wilson [Instituto Federal de Educacao, Ciencia e Tecnologia de Pernambuco, Recife, PE (Brazil); Lima, Fernando R.A., E-mail: falima@cnen.gov.b [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2011-10-26

    This paper performs a new type of dosimetric evaluation, where it was used a phantom of pathological voxels (representative phantom of sick person). The software VAP3D (Visualization and Analysis of Phantoms 3D) were used for, from a healthy phantom (phantom representative of healthy person), to introduce three dimensional regions to simulate tumors. It was used the Monte Carlo ESGnrc code to simulate the X ray photon transport, his interaction with matter and evaluation of absorbed dose in organs and tissues from thorax region of the healthy phantom and his pathological version. This is a computer model of typical exposure for programming the treatments in radiodiagnostic

  10. Acquired experience on organizing 3D S.UN.COP: international course to support nuclear license by user training in the areas of scaling, uncertainty, and 3D thermal-hydraulics/neutron-kinetics coupled codes

    International Nuclear Information System (INIS)

    Thermal-hydraulic system computer codes are extensively used worldwide for analysis of nuclear facilities by utilities, regulatory bodies, nuclear power plant designers, vendors, and research organizations. Computer code user represents a source of uncertainty that may significantly affect the results of system code calculations. Code user training and qualification represent an effective means for reducing the variation of results caused by the application of the codes by different users. This paper describes the experience in applying a systematic approach to training code users who, upon completion of the training, should be able to perform calculations making the best possible use of the capabilities of best estimate codes. In addition, this paper presents the organization and the main features of the 3D S.UN.COP (scaling, uncertainty, and 3D coupled code calculations) seminars during which particular emphasis is given to practical applications in connection with the licensing process of best estimate plus uncertainty methodologies, showing the designer, utility and regulatory approaches. (author)

  11. Acquired experience on organizing 3D S.UN.COP: international course to support nuclear license by user training in the areas of scaling, uncertainty, and 3D thermal-hydraulics/neutron-kinetics coupled codes

    Energy Technology Data Exchange (ETDEWEB)

    Petruzzi, Alessandro; D' Auria, Francesco [University of Pisa, San Piero a Grado (Italy). Nuclear Research Group San Piero a Grado (GRNSPG); Galetti, Regina, E-mail: regina@cnen.gov.b [National Commission for Nuclear Energy (CNEN), Rio de Janeiro, RJ (Brazil); Bajs, Tomislav [University of Zagreb (Croatia). Fac. of Electrical Engineering and Computing. Dept. of Power Systems; Reventos, Francesc [Technical University of Catalonia, Barcelona (Spain). Dept. of Physics and Nuclear Engineering

    2011-07-01

    Thermal-hydraulic system computer codes are extensively used worldwide for analysis of nuclear facilities by utilities, regulatory bodies, nuclear power plant designers, vendors, and research organizations. Computer code user represents a source of uncertainty that may significantly affect the results of system code calculations. Code user training and qualification represent an effective means for reducing the variation of results caused by the application of the codes by different users. This paper describes the experience in applying a systematic approach to training code users who, upon completion of the training, should be able to perform calculations making the best possible use of the capabilities of best estimate codes. In addition, this paper presents the organization and the main features of the 3D S.UN.COP (scaling, uncertainty, and 3D coupled code calculations) seminars during which particular emphasis is given to practical applications in connection with the licensing process of best estimate plus uncertainty methodologies, showing the designer, utility and regulatory approaches. (author)

  12. Close-range optical measurement of aircraft's 3D attitude and accuracy evaluation

    Institute of Scientific and Technical Information of China (English)

    Zhe Li; Zhenliang Ding; Feng Yuan

    2008-01-01

    A new screen-spot imaging method based on optical measurement is proposed, which is applicable to the close-range measurement of aircraft's three-dimensional (3D) attitude parameters. Laser tracker is used to finish the global calibrations of the high-speed cameras and the fixed screens on test site, as well as to establish media-coordinate-frames among various coordinate systems. The laser cooperation object mounted on the aircraft surface projects laser beams on the screens and the high-speed cameras syn-chronously record the light-spots' position changing with aircraft attitude. The recorded image sequences are used to compute the aircraft attitude parameters. Based on the matrix analysis, the error sources of the measurement accuracy are analyzed, and the maximum relative error of this mathematical model is estimated. The experimental result shows that this method effectively makes the change of aircraft position distinguishable, and the error of this method is no more than 3' while the rotation angles of three axes are within a certain range.

  13. Fabrication of imitative cracks by 3D printing for electromagnetic nondestructive testing and evaluations

    Directory of Open Access Journals (Sweden)

    Noritaka Yusa

    2016-05-01

    Full Text Available This study demonstrates that 3D printing technology offers a simple, easy, and cost-effective method to fabricate artificial flaws simulating real cracks from the viewpoint of eddy current testing. The method does not attempt to produce a flaw whose morphology mirrors that of a real crack but instead produces a relatively simple artificial flaw. The parameters of this flaw that have dominant effects on eddy current signals can be quantitatively controlled. Three artificial flaws in type 316L austenitic stainless steel plates were fabricated using a powderbed-based laser metal additive manufacturing machine. The three artificial flaws were designed to have the same length, depth, and opening but different branching and electrical contacts between flaw surfaces. The flaws were measured by eddy current testing using an absolute type pancake probe. The signals due to the three flaws clearly differed from each other although the flaws had the same length and depth. These results were supported by subsequent destructive tests and finite element analyses.

  14. Dual-projection 3D-2D registration for surgical guidance: preclinical evaluation of performance and minimum angular separation

    Science.gov (United States)

    Uneri, A.; Otake, Y.; Wang, A. S.; Kleinszig, G.; Vogt, S.; Gallia, G. L.; Rigamonti, D.; Wolinsky, J.-P.; Gokaslan, Ziya L.; Khanna, A. J.; Siewerdsen, J. H.

    2014-03-01

    An algorithm for 3D-2D registration of CT and x-ray projections has been developed using dual projection views to provide 3D localization with accuracy exceeding that of conventional tracking systems. The registration framework employs a normalized gradient information (NGI) similarity metric and covariance matrix adaptation evolution strategy (CMAES) to solve for the patient pose in 6 degrees of freedom. Registration performance was evaluated in anthropomorphic head and chest phantoms, as well as a human torso cadaver, using C-arm projection views acquired at angular separations (Δ𝜃) ranging 0-178°. Registration accuracy was assessed in terms target registration error (TRE) and compared to that of an electromagnetic tracker. Studies evaluated the influence of C-arm magnification, x-ray dose, and preoperative CT slice thickness on registration accuracy and the minimum angular separation required to achieve TRE ~2 mm. The results indicate that Δ𝜃 as small as 10-20° is adequate to achieve TRE <2 mm with 95% confidence, comparable or superior to that of commercial trackers. The method allows direct registration of preoperative CT and planning data to intraoperative fluoroscopy, providing 3D localization free from conventional limitations associated with external fiducial markers, stereotactic frames, trackers, and manual registration. The studies support potential application to percutaneous spine procedures and intracranial neurosurgery.

  15. Evaluation of usefulness and availability for orthopedic surgery using clavicle fracture model manufactured by desktop 3D printer

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Wang Kyun [Dept. of Diagnostic Radiology, Cheongju Medical Center, Cheongju (Korea, Republic of)

    2014-09-15

    Usefulness and clinical availability for surgery efficiency were evaluated by conducting pre-operative planning with a model manufactured by desktop 3D printer by using clavicle CT image. The patient-customized clavicle fracture model was manufactured by desktop 3D printer of FDM wire laminated processing method by converting the CT image into STL file in Open Source DICOM Viewer Osirix. Also, the model of the original shape before damaged was restored and manufactured by Mirror technique based on STL file of not fractured clavicle of the other side by using the symmetry feature of the human body. For the model, the position and size, degree of the fracture was equally printed out. Using the clavicle model directly manufactured with low cost and less time in Department of Radiology is considered to be useful because it can reduce secondary damage during surgery and increase surgery efficiency with Minimal invasive percutaneous plate osteosynthesis(MIPO)

  16. Evaluation of usefulness and availability for orthopedic surgery using clavicle fracture model manufactured by desktop 3D printer

    International Nuclear Information System (INIS)

    Usefulness and clinical availability for surgery efficiency were evaluated by conducting pre-operative planning with a model manufactured by desktop 3D printer by using clavicle CT image. The patient-customized clavicle fracture model was manufactured by desktop 3D printer of FDM wire laminated processing method by converting the CT image into STL file in Open Source DICOM Viewer Osirix. Also, the model of the original shape before damaged was restored and manufactured by Mirror technique based on STL file of not fractured clavicle of the other side by using the symmetry feature of the human body. For the model, the position and size, degree of the fracture was equally printed out. Using the clavicle model directly manufactured with low cost and less time in Department of Radiology is considered to be useful because it can reduce secondary damage during surgery and increase surgery efficiency with Minimal invasive percutaneous plate osteosynthesis(MIPO)

  17. Improved treatments for evaluating horizontal magnetic components through the 3-D FDM in E-polarization induction problems

    Institute of Scientific and Technical Information of China (English)

    陈伯舫

    2002-01-01

    To improve the accuracy of the numerical evaluation through the 3-D finite difference method, the surface boundary conditions are added to modify the old program. The author has tested the new program by making calculations for the model constructed by Wanamaker, et al (1984). The comparison between the numerical results obtained from this paper and those by Wannamaker, et al (1984) indicates that a pronounced improvement is realized in the evaluation of the horizontal magnetic components. Moreover, better calculations for the vertical magnetic components are also obtainable by using the new program.

  18. Technical Note: Immunohistochemical evaluation of mouse brain irradiation targeting accuracy with 3D-printed immobilization device

    International Nuclear Information System (INIS)

    Purpose: Small animal immobilization devices facilitate positioning of animals for reproducible imaging and accurate focal radiation therapy. In this study, the authors demonstrate the use of three-dimensional (3D) printing technology to fabricate a custom-designed mouse head restraint. The authors evaluate the accuracy of this device for the purpose of mouse brain irradiation. Methods: A mouse head holder was designed for a microCT couch using CAD software and printed in an acrylic based material. Ten mice received half-brain radiation while positioned in the 3D-printed head holder. Animal placement was achieved using on-board image guidance and computerized asymmetric collimators. To evaluate the precision of beam localization for half-brain irradiation, mice were sacrificed approximately 30 min after treatment and brain sections were stained for γ-H2AX, a marker for DNA breaks. The distance and angle of the γ-H2AX radiation beam border to longitudinal fissure were measured on histological samples. Animals were monitored for any possible trauma from the device. Results: Visualization of the radiation beam on ex vivo brain sections with γ-H2AX immunohistochemical staining showed a sharp radiation field within the tissue. Measurements showed a mean irradiation targeting error of 0.14 ± 0.09 mm (standard deviation). Rotation between the beam axis and mouse head was 1.2° ± 1.0° (standard deviation). The immobilization device was easily adjusted to accommodate different sizes of mice. No signs of trauma to the mice were observed from the use of tooth block and ear bars. Conclusions: The authors designed and built a novel 3D-printed mouse head holder with many desired features for accurate and reproducible radiation targeting. The 3D printing technology was found to be practical and economical for producing a small animal imaging and radiation restraint device and allows for customization for study specific needs

  19. Technical Note: Immunohistochemical evaluation of mouse brain irradiation targeting accuracy with 3D-printed immobilization device

    Energy Technology Data Exchange (ETDEWEB)

    Zarghami, Niloufar, E-mail: nzargham@uwo.ca; Jensen, Michael D. [Department of Medical Biophysics, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); Talluri, Srikanth; Dick, Frederick A. [Department of Biochemistry, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); London Regional Cancer Program, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 5W9 (Canada); Foster, Paula J. [Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Ontario N6A 5K8 (Canada); Department of Medical Biophysics, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); Chambers, Ann F. [Department of Medical Biophysics, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); Department of Oncology, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); London Regional Cancer Program, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 5W9 (Canada); Wong, Eugene [Department of Physics and Astronomy, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); Department of Medical Biophysics, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); Department of Oncology, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7 (Canada); London Regional Cancer Program, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 5W9 (Canada)

    2015-11-15

    Purpose: Small animal immobilization devices facilitate positioning of animals for reproducible imaging and accurate focal radiation therapy. In this study, the authors demonstrate the use of three-dimensional (3D) printing technology to fabricate a custom-designed mouse head restraint. The authors evaluate the accuracy of this device for the purpose of mouse brain irradiation. Methods: A mouse head holder was designed for a microCT couch using CAD software and printed in an acrylic based material. Ten mice received half-brain radiation while positioned in the 3D-printed head holder. Animal placement was achieved using on-board image guidance and computerized asymmetric collimators. To evaluate the precision of beam localization for half-brain irradiation, mice were sacrificed approximately 30 min after treatment and brain sections were stained for γ-H2AX, a marker for DNA breaks. The distance and angle of the γ-H2AX radiation beam border to longitudinal fissure were measured on histological samples. Animals were monitored for any possible trauma from the device. Results: Visualization of the radiation beam on ex vivo brain sections with γ-H2AX immunohistochemical staining showed a sharp radiation field within the tissue. Measurements showed a mean irradiation targeting error of 0.14 ± 0.09 mm (standard deviation). Rotation between the beam axis and mouse head was 1.2° ± 1.0° (standard deviation). The immobilization device was easily adjusted to accommodate different sizes of mice. No signs of trauma to the mice were observed from the use of tooth block and ear bars. Conclusions: The authors designed and built a novel 3D-printed mouse head holder with many desired features for accurate and reproducible radiation targeting. The 3D printing technology was found to be practical and economical for producing a small animal imaging and radiation restraint device and allows for customization for study specific needs.

  20. One-step reconstruction with a 3D-printed, biomechanically evaluated custom implant after complex pelvic tumor resection.

    Science.gov (United States)

    Wong, K C; Kumta, S M; Geel, N V; Demol, J

    2015-01-01

    Resection of a pelvic tumor is challenging because of its complex three-dimensional (3D) anatomy and deep-seated location with nearby vital structures. The resection is technically demanding if a custom implant is used for reconstruction of the bone defect as the surgeon needs to ensure the resection margin is sufficiently wide and the orientation of intended resection planes must match that of the custom implant. We describe a novel workflow of performing a partial acetabular resection in a patient with pelvic chondrosarcoma and reconstruction with a custom pelvic implant in a one-step operation. A multi-planar bone resection was virtually planned. A computer-aided design implant that both matched the bone defect and biomechanically evaluated was prefabricated with 3D printing technology. The 3D-printed patient-specific instruments (PSIs) were used to reproduce the same planned resection. The histology of the tumor specimen showed a clear resection margin. The errors of the achieved resection and implant position were deviating (1-4 mm) from the planned. The patient could walk unaided with a good hip function. No tumor recurrence and implant loosening were noted at 11 months after surgery. The use of this novel CT-based method for surgical planning, the engineering software for implant design and validation, together with 3D printing technology for implant and PSI fabrication makes it possible to generate a personalized, biomechanically evaluated implant for accurate reconstruction after a pelvic tumor resection in a one-step operation. Further study in a larger population is needed to assess the clinical efficacy of the workflow in complex bone tumor surgery.

  1. Emulation-Based Transient Thermal Modeling of 2D/3D Systems-on-Chip with Active Cooling

    OpenAIRE

    Atienza, David

    2009-01-01

    New tendencies envisage 2D and 3D Multi-Processor Systems-On-Chip (MPSoCs) as a promising solution for the consumer electronics market. MPSoCs are complex to design, as they must execute multiple applications (games, video), while meeting additional design constraints (energy consumption, time-to-market, etc.). Moreover, the rise of temperature in the die for MPSoCs, especially for forthcoming 3D chips, can seriously affect their final performance and reliability. In this context, transient t...

  2. Evaluation of occlusal rest seats with 3D technology in dental education.

    Science.gov (United States)

    Sampaio-Fernandes, Manuel António Ferreira; Sampaio-Fernandes, Maria M; Fonseca, Patrícia A; Almeida, Paulo R; Reis-Campos, José C; Figueiral, Maria H

    2015-02-01

    The preparation of rest seats must comply with specific sizes and shapes. Various technological systems such as Kavo PrepAssistant have been used as an auxiliary method to evaluate preclinical preparations more objectively. The aims of this study were to establish an alternative system for evaluating occlusal rest seats and to compare different types of assessment. Seventy-six undergraduate students at Oporto University Faculty of Dental Medicine in Portugal were selected as a convenience sample to prepare two occlusal rest seats in Kavo teeth #45 and #46 (FDI World Dental Federation ISO-3950) and were randomly assigned to two groups. Bearing in mind the ideal characteristics of rest seats, the investigators defined ten assessment parameters, and their evaluation weights were independently estimated by three evaluators. Four of these parameters were measured in Kavo PrepAssistant. The results of the different evaluation methods and evaluators varied considerably. The classical evaluation presented final results worse than those of the evaluations using parameters. In this study, carrying out the assessment with Kavo PrepAssistant helped to achieve a more objective and less evaluator-dependent final evaluation.

  3. RELAP5-3D{sup C} three dimensional neutron kinetics coupled thermal-hydraulics analyses of the Atucha-2 PHWR

    Energy Technology Data Exchange (ETDEWEB)

    Parisi, C.; D' Auria, F. [GRNSPG / University of Pisa, Pisa (Italy); Mazzantini, O. [NA-SA, Buenos Aires (Argentina); Ivanov, K.N. [RDFMG / The Pennsylvania State University, State College, PA (United States)

    2008-07-01

    In the framework of the Agreement 'NA-SA - University of Pisa', a detailed RELAP5-3D{sup C} model of the under construction Atucha-2 PHWR was developed. The aim of this activity was to have a state-of-the-art tool for performing realistic safety analyses for the licensing of Atucha-2. In this paper, the main steps for the development and the qualification of the RELAP5-3D{sup C} model as well as some sample applications for the safety analyses (0.1 LOCA, Fuel Channel blockage) are reported. After the definition of a relevant core status with fuel at the burnup equilibrium, a set of neutron cross section libraries were calculated by the lattice physics code HELIOS. These data were used for the setting up of a RELAP5-3D{sup C} Neutron Kinetic (NK) model of the core that was then coupled with a RELAP5-3D{sup C} Thermal-Hydraulic (TH) model of the whole plant. The TH model is based on a 280 Fuel Channels (FCs) and a 3D moderator tank nodalization. The 3D NK model is representing all the FCs, the reflectors and the oblique Control Rods (CR). The boundary conditions for the reconstruction of the boron clouds, injected in the moderator tank by the shut-down emergency system, were derived by previously executed Computational Fluid-dynamics (CFD) analyses by the CFX code. Finally, applications of the developed 3D NK-TH model to sample safety analyses demonstrated its state-of-the-art capabilities and its high level of realism. (authors)

  4. 3D thermal hydraulic simulation of the hot channel of a typical material testing reactor under normal operation conditions

    Energy Technology Data Exchange (ETDEWEB)

    El-Morshedy, Salah El-Din; Salama, Amgad [Atomic Energy Authority, Cairo (Egypt). Reactors Dept.

    2010-09-15

    The hot channel in a typical Material Testing Reactor (MTR) is subjected to 3D simulation. Because of the existence of similarity planes, only a quarter of the hot channel including meat thickness, clad, and coolant channel is considered for CFD analysis using the FLUENT code. For the simulation, steady state normal operation regime at the reactor nominal power is assumed. In order to build confidence in our modeling approach, the results obtained in this work are compared with those obtained from the one-dimensional simulation code, MTRTHA. That is, modified variables were generated in order to match those obtained by MTRTHA and to allow comparisons. Quite good agreement is generally observed, however, the maximum clad surface temperature predicted by the 3D calculations, located at the clad mid-width, is higher than the 1D prediction by about 8 C but still below the onset of subcooled boiling by adequate safety margin. The results show quite interesting 3D patterns in both the flow field and the heat transfer. Temperature profiles, velocity profiles and contours are all presented to highlight the essential 3D features of this system. (orig.)

  5. A protocol for evaluating the accuracy of 3D body scanners

    NARCIS (Netherlands)

    Kouchi, M.; Mochimaru, M.; Bradtmiller, B.; Daanen, H.A.M.; Li, P.; Nacher, B.A.; Nam, Y.

    2012-01-01

    Scan-derived landmarks locations and surface shapes are more and more used, but there is no commonly accepted protocol for evaluating the accuracy of these measurements. Therefore we propose a protocol for evaluating the accuracy of surface shape and the repeatability of scan-derived landmark locati

  6. Perceptual Evaluation of Photo-Realism in Real-Time 3D Augmented Reality

    DEFF Research Database (Denmark)

    Borg, Mathias; Paprocki, Martin Marko; Madsen, Claus B.

    2014-01-01

    We present a framework for creating photo-realism of three-dimensional augmented objects, as well as a perceptual evaluating of the scenes. A setup utilizing different lighting conditions is created. Different parameters affecting the realism are evaluated. These are camera artefacts, shadows...

  7. MDCT angiography with 3D image reconstructions in the evaluation of failing arteriovenous fistulas and grafts in hemodialysis patients

    Energy Technology Data Exchange (ETDEWEB)

    Dimopoulou, Angeliki; Raland, Hans; Magnusson, Anders (Dept. of Radiology, Univ. Hospital, Uppsala (Sweden)), email: angeliki.dimopoulou@akademiska.se; Wikstroem, Bjoern (Dept. of Medical Sciences, Renal Section, Univ. Hospital, Uppsala (Sweden))

    2011-11-15

    Background. Arteriovenous fistulas and grafts are the methods of choice for vascular access in renal failure patients in need of hemodialysis. Their major complication, however, is stenosis, which might lead to thrombosis. Purpose. To demonstrate the usefulness of 16-MDCTA with 3D image reconstructions, in long-term hemodialysis patients with dysfunctional arteriovenous fistulas and grafts (AVF and AVG). Material and Methods. During a 17-month period, 31 patients with dysfunctional AVF and AVG (24 AVF and seven AVG) were examined with MDCTA with 3D image postprocessing. Parameters such as comprehension of the anatomy, quality of contrast enhancement, and pathological vascular changes were measured. DSA was then performed in 24 patients. Results. MDCTA illustrated the anatomy of the AVF/AVG and the entire vascular tree to the heart, in a detailed and comprehensive manner in 93.5% of the evaluated segments, and depicted pathology of AVF/AVG or pathology of the associated vasculature. MDCTA demonstrated a total of 38 significant stenoses in 25 patients. DSA verified 37 stenoses in 24 patients and demonstrated two additional stenoses. MDCTA had thus a sensitivity of 95%. All 24 patients were treated with percutaneous transluminal angioplasty (PTA) with good technical results. Conclusion. MDCTA with 3D reconstructions of dysfunctioning AVFs and AVGs in hemodialysis patients is an accurate and reliable diagnostic method helping customize future intervention

  8. Plaque characterization in ex vivo MRI evaluated by dense 3D correspondence with histology

    DEFF Research Database (Denmark)

    Engelen, A. van; de Bruijne, Marleen; Klein, S.;

    2011-01-01

    registration of histology data with ex vivo MRI data, using non-rigid registration, both for training and evaluation. This is more objective than previously presented methods, as it eliminates selection bias that is introduced when 2D MRI slices are manually matched to histological slices before evaluation....... Histological slices of human atherosclerotic plaques were manually segmented into necrotic core, fibrous tissue and calcification. Classification of these three components was voxelwise evaluated. As features the intensity, gradient magnitude and Laplacian in four MRI sequences after different degrees...

  9. Evaluating the Potential of Rtk-Uav for Automatic Point Cloud Generation in 3d Rapid Mapping

    Science.gov (United States)

    Fazeli, H.; Samadzadegan, F.; Dadrasjavan, F.

    2016-06-01

    During disaster and emergency situations, 3D geospatial data can provide essential information for decision support systems. The utilization of geospatial data using digital surface models as a basic reference is mandatory to provide accurate quick emergency response in so called rapid mapping activities. The recipe between accuracy requirements and time restriction is considered critical in this situations. UAVs as alternative platforms for 3D point cloud acquisition offer potentials because of their flexibility and practicability combined with low cost implementations. Moreover, the high resolution data collected from UAV platforms have the capabilities to provide a quick overview of the disaster area. The target of this paper is to experiment and to evaluate a low-cost system for generation of point clouds using imagery collected from a low altitude small autonomous UAV equipped with customized single frequency RTK module. The customized multi-rotor platform is used in this study. Moreover, electronic hardware is used to simplify user interaction with the UAV as RTK-GPS/Camera synchronization, and beside the synchronization, lever arm calibration is done. The platform is equipped with a Sony NEX-5N, 16.1-megapixel camera as imaging sensor. The lens attached to camera is ZEISS optics, prime lens with F1.8 maximum aperture and 24 mm focal length to deliver outstanding images. All necessary calibrations are performed and flight is implemented over the area of interest at flight height of 120 m above the ground level resulted in 2.38 cm GSD. Earlier to image acquisition, 12 signalized GCPs and 20 check points were distributed in the study area and measured with dualfrequency GPS via RTK technique with horizontal accuracy of σ = 1.5 cm and vertical accuracy of σ = 2.3 cm. results of direct georeferencing are compared to these points and experimental results show that decimeter accuracy level for 3D points cloud with proposed system is achievable, that is suitable

  10. EVALUATION OF THE LIVER METASTASIS BY 3D-COMPUTED TOMOGRAPHY

    OpenAIRE

    Iuliana Eva; R.C. Tiutiuca

    2005-01-01

    Abdominal spiral computed tomography is the method of choice for the diagnosis of hepatic metastasis, evaluating lesions even under 10 mm. Treatment depends of the hepatic and extrahepatic spread of disease. Therapeutical options include surgical ablation (resection, enucleation, crioablation, radiofrequency, liver transplant) or non-surgical (embolization or chemoembolization, therapeutic aproach through the hepatic artery). Precise diagnostic and evaluation of the extension of the disease...

  11. A 3D Lumped Thermal Network Model for Long-term Load Profiles Analysis in High Power IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Ghimire, Pramod;

    2016-01-01

    )-based simulation is another method which is often used to analyze the steady-state thermal distribution of IGBT modules, but it is not possible to be used for long-term analysis of load profiles of power converter, which is needed for reliability assessments and better thermal design. This paper proposes a novel......The conventional RC lumped thermal networks are widely used to estimate the temperature of power devices, but they are lack of accuracy in addressing detailed thermal behaviors/couplings in different locations and layers of the high power IGBT modules. On the other hand, Finite Element (FE...... three-dimensional RC lumped thermal network for the high power IGBT modules. The thermal-coupling effects among the chips and among the critical layers are modelled, and boundary conditions including the cooling conditions are also taken into account. It is concluded that, the proposed thermal model...

  12. A 3D reconstruction method of the body envelope from biplanar X-rays: Evaluation of its accuracy and reliability

    OpenAIRE

    NEROT, Agathe; CHOISNE, Julie; AMABILE, Célia; TRAVERT, Christophe; PILLET, Hélène; WANG Xuguang; Skalli, W.

    2015-01-01

    The aim of this study was to propose a novel method for reconstructing the external body envelope from the low dose biplanar X-rays of a person. The 3D body envelope was obtained by deforming a template to match the surface profiles in two X-rays images in three successive steps: global morphing to adopt the position of a person and scale the templateós body segments, followed by a gross deformation and a fine deformation using two sets of pre-defined control points. To evaluate the method, a...

  13. Radiochromic 3D Detectors

    Science.gov (United States)

    Oldham, Mark

    2015-01-01

    Radiochromic materials exhibit a colour change when exposed to ionising radiation. Radiochromic film has been used for clinical dosimetry for many years and increasingly so recently, as films of higher sensitivities have become available. The two principle advantages of radiochromic dosimetry include greater tissue equivalence (radiologically) and the lack of requirement for development of the colour change. In a radiochromic material, the colour change arises direct from ionising interactions affecting dye molecules, without requiring any latent chemical, optical or thermal development, with important implications for increased accuracy and convenience. It is only relatively recently however, that 3D radiochromic dosimetry has become possible. In this article we review recent developments and the current state-of-the-art of 3D radiochromic dosimetry, and the potential for a more comprehensive solution for the verification of complex radiation therapy treatments, and 3D dose measurement in general.

  14. Sensors for 3D Imaging: Metric Evaluation and Calibration of a CCD/CMOS Time-of-Flight Camera

    Directory of Open Access Journals (Sweden)

    Fulvio Rinaudo

    2009-12-01

    Full Text Available 3D imaging with Time-of-Flight (ToF cameras is a promising recent technique which allows 3D point clouds to be acquired at video frame rates. However, the distance measurements of these devices are often affected by some systematic errors which decrease the quality of the acquired data. In order to evaluate these errors, some experimental tests on a CCD/CMOS ToF camera sensor, the SwissRanger (SR-4000 camera, were performed and reported in this paper. In particular, two main aspects are treated: the calibration of the distance measurements of the SR-4000 camera, which deals with evaluation of the camera warm up time period, the distance measurement error evaluation and a study of the influence on distance measurements of the camera orientation with respect to the observed object; the second aspect concerns the photogrammetric calibration of the amplitude images delivered by the camera using a purpose-built multi-resolution field made of high contrast targets.

  15. Sensors for 3D Imaging: Metric Evaluation and Calibration of a CCD/CMOS Time-of-Flight Camera.

    Science.gov (United States)

    Chiabrando, Filiberto; Chiabrando, Roberto; Piatti, Dario; Rinaudo, Fulvio

    2009-01-01

    3D imaging with Time-of-Flight (ToF) cameras is a promising recent technique which allows 3D point clouds to be acquired at video frame rates. However, the distance measurements of these devices are often affected by some systematic errors which decrease the quality of the acquired data. In order to evaluate these errors, some experimental tests on a CCD/CMOS ToF camera sensor, the SwissRanger (SR)-4000 camera, were performed and reported in this paper. In particular, two main aspects are treated: the calibration of the distance measurements of the SR-4000 camera, which deals with evaluation of the camera warm up time period, the distance measurement error evaluation and a study of the influence on distance measurements of the camera orientation with respect to the observed object; the second aspect concerns the photogrammetric calibration of the amplitude images delivered by the camera using a purpose-built multi-resolution field made of high contrast targets.

  16. Evaluation of a Backpack-Mounted 3D Mobile Scanning System

    Directory of Open Access Journals (Sweden)

    Helge A. Lauterbach

    2015-10-01

    Full Text Available Recently, several backpack-mounted systems, also known as personal laser scanning systems, have been developed. They consist of laser scanners or cameras that are carried by a human operator to acquire measurements of the environment while walking. These systems were first designed to overcome the challenges of mapping indoor environments with doors and stairs. While the human operator inherently has the ability to open doors and to climb stairs, the flexible movements introduce irregularities of the trajectory to the system. To compete with other mapping systems, the accuracy of these systems has to be evaluated. In this paper, we present an extensive evaluation of our backpack mobile mapping system in indoor environments. It is shown that the system can deal with the normal human walking motion, but has problems with irregular jittering. Moreover, we demonstrate the applicability of the backpack in a suitable urban scenario.

  17. Mining 3D Patterns from Gene Expression Temporal Data: A New Tricluster Evaluation Measure

    OpenAIRE

    David Gutiérrez-Avilés; Cristina Rubio-Escudero

    2014-01-01

    Microarrays have revolutionized biotechnological research. The analysis of new data generated represents a computational challenge due to the characteristics of these data. Clustering techniques are applied to create groups of genes that exhibit a similar behavior. Biclustering emerges as a valuable tool for microarray data analysis since it relaxes the constraints for grouping, allowing genes to be evaluated only under a subset of the conditions. However, if a third dimension appears in the ...

  18. Evaluating affective feedback of the 3D agent Max in a competitive cards game

    OpenAIRE

    Becker-Asano, Christian; Prendinger, Helmut; Ishizuka, Mitsuro; Wachsmuth, Ipke; Tao, Jianhua; Tan, Tieniu; Picard, Rosalind W.

    2005-01-01

    Within the field of Embodied Conversational Agents (ECAs), the simulation of emotions has been suggested as a means to enhance the believability of ECAs and also to effectively contribute to the goal of more intuitive human–computer interfaces. Although various emotion models have been proposed, results demonstrating the appropriateness of displaying particular emotions within ECA applications are scarce or even inconsistent. Worse, questionnaire methods often seem insufficient to evaluate th...

  19. 3D GIS BASED EVALUATION OF THE AVAILABLE SIGHT DISTANCE TO ASSESS SAFETY OF URBAN ROADS

    Directory of Open Access Journals (Sweden)

    M. Bassani

    2015-08-01

    Full Text Available The available sight distance (ASD in front of the driver to detect possible conflicts with unexpected obstacles is fundamental for traffic safety. In the last 20 years, road design software (RDS has been continuously updated with dedicated modules to estimate ASD, thus assessing the quality of project from a safety point of view. Unfortunately, the evaluation of ASD still represents an issue in the case of existing road, and the object of discussion in the research community. To avoid problems related to the limitation associated with the use of digital terrain models typically employed in RDS, the Geographic Information Systems (GIS software can use digital surface models (DSM which are more flexible in the modelling of sight obstruction due to vegetation, street furniture, and vertical surfaces largely diffused in urbanized areas. The paper deals with the evaluation of GIS in the estimation of ASD in a typical urban road where the density of sight obstruction along the roadside is relatively high. The work explores the case study of a collector road in the city of Turin (Italy. Results confirm the potentiality of GIS software in capturing the complex morphology of the urban environment, thus confirming that GIS could become an important analysis tool for road engineers in the field of road safety. The investigation here described is part of the Pro-VISION Project (funded in 2014 by the Regione Piemonte, Italy.

  20. Evaluation of a 3-D rockfall module within a forest patch model

    Directory of Open Access Journals (Sweden)

    W. Rammer

    2010-04-01

    Full Text Available Many slopes in the Alps are prone to rockfall and forests play a vital role in protecting objects such as (rail roads and infrastructure against rockfall. Decision support tools are required to assess rockfall processes and to quantify the rockfall protection effect of forest stands. This paper presents results of an iterative sequence of tests and improvements of a coupled rockfall and forest dynamics model with focus on the rockfall module. As evaluation data a real-size rockfall experiment in the French Alps and two 2-D rockfall trajectories from Austria and Switzerland were used. Modification of the rebound algorithm and the inclusion of an algorithm accounting for the sudden halt of falling rocks due to surface roughness greatly improved the correspondence between simulated and observed key rockfall variables like run-out distances, rebound heights and jump lengths for the real-size rockfall experiment. Moreover, the observed jump lengths and run-out distances of the 2-D trajectories were well within the stochastic range of variation yielded by the simulations. Based on evaluation results it is concluded that the rockfall model can be employed to assess the protective effect of forest vegetation.

  1. 3-D VARIABLE PARAMETER NUMERICAL MODEL FOR EVALUATION OF THE PLANNED EXPLOITABLE GROUNDWATER RESOURCE IN REGIONAL UNCONSOLIDATED SEDIMENTS

    Institute of Scientific and Technical Information of China (English)

    LUO Zu-jiang; WANG Yan

    2012-01-01

    In order to correctly evaluate the exploitable groundwater resource in regional complex,thick Quaternary unconsolidated sediments,the whole Quaternary unconsolidated sediments are considered as a unified hydrogeological unit and a 3-D unsteady groundwater flow numerical model is adopted.Meanwhile,with the consideration of the dynamic changes of the porosity,the hydraulic conductivity and the specific storage with the groundwater level dropping during the exploitation process,an improved composite element seepage matrix adjustment method is applied to solve the unsteady flow problem of free surface.In order to evaluate the exploitable groundwater resource in Cangzhou,Hebei Province,the hydrogeological conceptual model of Cangzhou is generalized to establish,a 3-D variable parameter numerical model of Cangzhou.Based on the prediction of the present groundwater exploitation,and by adjusting the groundwater exploitation layout,the exploitable groundwater resource is predicted.The model enjoys features like good convergence,good stability and high precision.

  2. Segmentation Based Classification of 3D Urban Point Clouds: A Super-Voxel Based Approach with Evaluation

    Directory of Open Access Journals (Sweden)

    Laurent Trassoudaine

    2013-03-01

    Full Text Available Segmentation and classification of urban range data into different object classes have several challenges due to certain properties of the data, such as density variation, inconsistencies due to missing data and the large data size that require heavy computation and large memory. A method to classify urban scenes based on a super-voxel segmentation of sparse 3D data obtained from LiDAR sensors is presented. The 3D point cloud is first segmented into voxels, which are then characterized by several attributes transforming them into super-voxels. These are joined together by using a link-chain method rather than the usual region growing algorithm to create objects. These objects are then classified using geometrical models and local descriptors. In order to evaluate the results, a new metric that combines both segmentation and classification results simultaneously is presented. The effects of voxel size and incorporation of RGB color and laser reflectance intensity on the classification results are also discussed. The method is evaluated on standard data sets using different metrics to demonstrate its efficacy.

  3. Fabrication and evaluation of electrohydrodynamic jet 3D printed polycaprolactone/chitosan cell carriers using human embryonic stem cell-derived fibroblasts.

    Science.gov (United States)

    Wu, Yang; Sriram, Gopu; Fawzy, Amr S; Fuh, Jerry Yh; Rosa, Vinicius; Cao, Tong; Wong, Yoke San

    2016-08-01

    Biological function of adherent cells depends on the cell-cell and cell-matrix interactions in three-dimensional space. To understand the behavior of cells in 3D environment and their interactions with neighboring cells and matrix requires 3D culture systems. Here, we present a novel 3D cell carrier scaffold that provides an environment for routine 3D cell growth in vitro We have developed thin, mechanically stable electrohydrodynamic jet (E-jet) 3D printed polycaprolactone and polycaprolactone/Chitosan macroporous scaffolds with precise fiber orientation for basic 3D cell culture application. We have evaluated the application of this technology by growing human embryonic stem cell-derived fibroblasts within these 3D scaffolds. Assessment of cell viability and proliferation of cells seeded on polycaprolactone and polycaprolactone/Chitosan 3D-scaffolds show that the human embryonic stem cell-derived fibroblasts could adhere and proliferate on the scaffolds over time. Further, using confocal microscopy we demonstrate the ability to use fluorescence-labelled cells that could be microscopically monitored in real-time. Hence, these 3D printed polycaprolactone and polycaprolactone/Chitosan scaffolds could be used as a cell carrier for in vitro 3D cell culture-, bioreactor- and tissue engineering-related applications in the future. PMID:27252227

  4. Development and Evaluation of a UAV-Photogrammetry System for Precise 3D Environmental Modeling

    Science.gov (United States)

    Shahbazi, Mozhdeh; Sohn, Gunho; Théau, Jérôme; Menard, Patrick

    2015-01-01

    The specific requirements of UAV-photogrammetry necessitate particular solutions for system development, which have mostly been ignored or not assessed adequately in recent studies. Accordingly, this paper presents the methodological and experimental aspects of correctly implementing a UAV-photogrammetry system. The hardware of the system consists of an electric-powered helicopter, a high-resolution digital camera and an inertial navigation system. The software of the system includes the in-house programs specifically designed for camera calibration, platform calibration, system integration, on-board data acquisition, flight planning and on-the-job self-calibration. The detailed features of the system are discussed, and solutions are proposed in order to enhance the system and its photogrammetric outputs. The developed system is extensively tested for precise modeling of the challenging environment of an open-pit gravel mine. The accuracy of the results is evaluated under various mapping conditions, including direct georeferencing and indirect georeferencing with different numbers, distributions and types of ground control points. Additionally, the effects of imaging configuration and network stability on modeling accuracy are assessed. The experiments demonstrated that 1.55 m horizontal and 3.16 m vertical absolute modeling accuracy could be achieved via direct geo-referencing, which was improved to 0.4 cm and 1.7 cm after indirect geo-referencing. PMID:26528976

  5. Development and Evaluation of a UAV-Photogrammetry System for Precise 3D Environmental Modeling.

    Science.gov (United States)

    Shahbazi, Mozhdeh; Sohn, Gunho; Théau, Jérôme; Menard, Patrick

    2015-10-30

    The specific requirements of UAV-photogrammetry necessitate particular solutions for system development, which have mostly been ignored or not assessed adequately in recent studies. Accordingly, this paper presents the methodological and experimental aspects of correctly implementing a UAV-photogrammetry system. The hardware of the system consists of an electric-powered helicopter, a high-resolution digital camera and an inertial navigation system. The software of the system includes the in-house programs specifically designed for camera calibration, platform calibration, system integration, on-board data acquisition, flight planning and on-the-job self-calibration. The detailed features of the system are discussed, and solutions are proposed in order to enhance the system and its photogrammetric outputs. The developed system is extensively tested for precise modeling of the challenging environment of an open-pit gravel mine. The accuracy of the results is evaluated under various mapping conditions, including direct georeferencing and indirect georeferencing with different numbers, distributions and types of ground control points. Additionally, the effects of imaging configuration and network stability on modeling accuracy are assessed. The experiments demonstrated that 1.55 m horizontal and 3.16 m vertical absolute modeling accuracy could be achieved via direct geo-referencing, which was improved to 0.4 cm and 1.7 cm after indirect geo-referencing.

  6. Development and Evaluation of a UAV-Photogrammetry System for Precise 3D Environmental Modeling

    Directory of Open Access Journals (Sweden)

    Mozhdeh Shahbazi

    2015-10-01

    Full Text Available The specific requirements of UAV-photogrammetry necessitate particular solutions for system development, which have mostly been ignored or not assessed adequately in recent studies. Accordingly, this paper presents the methodological and experimental aspects of correctly implementing a UAV-photogrammetry system. The hardware of the system consists of an electric-powered helicopter, a high-resolution digital camera and an inertial navigation system. The software of the system includes the in-house programs specifically designed for camera calibration, platform calibration, system integration, on-board data acquisition, flight planning and on-the-job self-calibration. The detailed features of the system are discussed, and solutions are proposed in order to enhance the system and its photogrammetric outputs. The developed system is extensively tested for precise modeling of the challenging environment of an open-pit gravel mine. The accuracy of the results is evaluated under various mapping conditions, including direct georeferencing and indirect georeferencing with different numbers, distributions and types of ground control points. Additionally, the effects of imaging configuration and network stability on modeling accuracy are assessed. The experiments demonstrated that 1.55 m horizontal and 3.16 m vertical absolute modeling accuracy could be achieved via direct geo-referencing, which was improved to 0.4 cm and 1.7 cm after indirect geo-referencing.

  7. Systematic assessment and evaluation of sliding interleaved kY (SLINKY) acquisition for 3D MRA.

    Science.gov (United States)

    Liu, K; Lee, D H; Rutt, B K

    1998-01-01

    In comparison with the conventional three-dimensional multiple overlapped thin slab acquisition (MOTSA) for magnetic resonance angiography (MRA), we have developed a novel sliding interleaved kY (SLINKY) acquisition technique, which can eliminate the slab boundary artifact (SBA) or venetian blind artifact without any a priori knowledge of blood flow. This work addresses the systematic assessment and evaluation of the SLINKY technique and verifies the advantages of SLINKY in the following several aspects: (a) scan time efficiency; (b) signal-to-noise ratio (SNR), and signal-difference-to-noise ratio (SDNR); (c) sensitivity to flow velocity range; (d) sensitivity to flow direction; (e) signal loss in slow/reversal flow regions; and (f) reconstruction efficiency and feasibility. Both phantom and in vivo experiments verify the clinical significance of the technique. The new MRA images acquired with this imaging technique in 31 volunteer/patient examinations show highly reliable mapping of vascular morphology without the SBA and reduction of signal voids in complex/slow flow regions. PMID:9702894

  8. Development and Evaluation of a UAV-Photogrammetry System for Precise 3D Environmental Modeling.

    Science.gov (United States)

    Shahbazi, Mozhdeh; Sohn, Gunho; Théau, Jérôme; Menard, Patrick

    2015-01-01

    The specific requirements of UAV-photogrammetry necessitate particular solutions for system development, which have mostly been ignored or not assessed adequately in recent studies. Accordingly, this paper presents the methodological and experimental aspects of correctly implementing a UAV-photogrammetry system. The hardware of the system consists of an electric-powered helicopter, a high-resolution digital camera and an inertial navigation system. The software of the system includes the in-house programs specifically designed for camera calibration, platform calibration, system integration, on-board data acquisition, flight planning and on-the-job self-calibration. The detailed features of the system are discussed, and solutions are proposed in order to enhance the system and its photogrammetric outputs. The developed system is extensively tested for precise modeling of the challenging environment of an open-pit gravel mine. The accuracy of the results is evaluated under various mapping conditions, including direct georeferencing and indirect georeferencing with different numbers, distributions and types of ground control points. Additionally, the effects of imaging configuration and network stability on modeling accuracy are assessed. The experiments demonstrated that 1.55 m horizontal and 3.16 m vertical absolute modeling accuracy could be achieved via direct geo-referencing, which was improved to 0.4 cm and 1.7 cm after indirect geo-referencing. PMID:26528976

  9. Evaluating Satellite Observed CO2 Column by a 3-D Atmospheric Transport Model

    International Nuclear Information System (INIS)

    Satellite remote sensing is the latest method of measuring atmospheric CO2, which covers a wide range and makes periodic observation. But due to lack of ground-based observation sites, global satellite observed CO2 column is not evaluated efficiently. This paper assess the applicability of using GEOS-Chem model to forward simulate atmospheric CO2 for verifying Greenhouse Gas Observation SATellite (GOSAT) observed CO2 column. It is shown that GEOS-Chem performs well in modelling atmospheric CO2 and there are generally no significant differences between ground-based observation and model results. According to the comparsion, the spatial and temporal distribution of XCO2 agrees well between GOSAT and GEOS-Chem. GOSAT XCO2 is turned out to be 2.6 ppm lower than the model results. The mean difference observed between GOSAT and GEOS-Chem varies from −1.8 to −3.1 ppm seasonally, with the standard deviation ranging from 1.4 to 2.1 ppm. And in general, the difference is larger in summer than that in winter, in land area than in sea area. It might have been caused by the different land-sea distribution and eco-system's changing with seasons

  10. Combining 3D human in vitro methods for a 3Rs evaluation of novel titanium surfaces in orthopaedic applications

    Science.gov (United States)

    Stevenson, G.; Rehman, S.; Draper, E.; Hernández‐Nava, E.; Hunt, J.

    2016-01-01

    ABSTRACT In this study, we report on a group of complementary human osteoblast in vitro test methods for the preclinical evaluation of 3D porous titanium surfaces. The surfaces were prepared by additive manufacturing (electron beam melting [EBM]) and plasma spraying, allowing the creation of complex lattice surface geometries. Physical properties of the surfaces were characterized by SEM and profilometry and 3D in vitro cell culture using human osteoblasts. Primary human osteoblast cells were found to elicit greater differences between titanium sample surfaces than an MG63 osteoblast‐like cell line, particularly in terms of cell survival. Surface morphology was associated with higher osteoblast metabolic activity and mineralization on rougher titanium plasma spray coated surfaces than smoother surfaces. Differences in osteoblast survival and metabolic activity on titanium lattice structures were also found, despite analogous surface morphology at the cellular level. 3D confocal microscopy identified osteoblast organization within complex titanium surface geometries, adhesion, spreading, and alignment to the biomaterial strut geometries. Mineralized nodule formation throughout the lattice structures was also observed, and indicative of early markers of bone in‐growth on such materials. Testing methods such as those presented are not traditionally considered by medical device manufacturers, but we suggest have value as an increasingly vital tool in efficiently translating pre‐clinical studies, especially in balance with current regulatory practice, commercial demands, the 3Rs, and the relative merits of in vitro and in vivo studies. Biotechnol. Bioeng. 2016;113: 1586–1599. © 2015 The Authors. Biotechnology and Bioengineering Published by Wiley Periodicals, Inc. PMID:26702609

  11. In vitro evaluation of the sinus sagittalis superior thrombosis model in the rat using 3D micro- and nanocomputed tomography

    International Nuclear Information System (INIS)

    Thrombosis of the cerebral veins and sinus are common causes of stroke. Animal models help us to understand the underlying pathophysiology of this condition. Therefore, the purpose of our study was to evaluate a well-established model for sinus sagittalis (SSS) thrombosis using micro- and nanocomputed tomography (CT) imaging. SSS thrombosis was performed in four rats. After contrast perfusion, brains were isolated and scanned using micro-CT at (8 μm)3 voxel size to generate 3D images of the cerebral vasculature. For more detailed information on vascular perfusion territories, nano-CT imaging was performed to investigate the boundary layer of contrast-enhanced vessels and the occluded veins. The venous and arterial vascular volume fraction and gray scale measurements were obtained in the SSS thrombosis group and compared to controls. The significance of differences in vascular volume fraction and gray scale measurements was tested with analysis of variance. Results were complemented with histology. Micro-CT proved to accurately visualize and differentiate vascular occlusion territories performed in the SSS thrombosis model. Moreover, 3D micro-CT provided quantitative information on arterial and venous vascular volume fraction. Micro-CT imaging enables a total 3D visualization of complications (ventricle rupture) in the SSS thrombosis model. We established gray scale measurements by which focal cerebral ischemia could be radiographically categorized (p < 0.001). Using nano-CT, the interface of contrast-perfused and occluded veins can be visualized. Micro-CT is feasible for analysis and differentiation of perfusion territories in an animal model of focal cerebral ischemia. (orig.)

  12. Evaluation and validation methods for intersubject nonrigid 3D image registration of the human brain

    Science.gov (United States)

    Guo, Ting; Starreveld, Yves P.; Peters, Terry M.

    2005-04-01

    This work presents methodologies for assessing the accuracy of non-rigid intersubject registration algorithms from both qualitative and quantitative perspectives. The first method was based on a set of 43 anatomical landmarks. MRI brain images of 12 subjects were non-rigidly registered to the standard MRI dataset. The "gold-standard" coordinates of the 43 landmarks in the target were estimated by averaging their coordinates after 6 tagging sessions. The Euclidean distance between each landmark of a subject after warping to the reference space and the homologous "gold-standard" landmark on the reference image was considered as the registration error. Another method based on visual inspection software displaying the spatial change of colour-coded spheres, before and after warping, was also developed to evaluate the performance of the non-rigid warping algorithms within the homogeneous regions in the deep-brain. Our methods were exemplified by assessing and comparing the accuracy of two intersubject non-rigid registration approaches, AtamaiWarp and ANIMAL algorithms. From the first method, the average registration error was 1.04mm +/- 0.65mm for AtamaiWarp, and 1.59mm +/- 1.47mm for ANIMAL. With maximum registration errors of 2.78mm and 3.90mm respectively, AtamaiWarp and ANIMAL located 58% and 35% landmarks respectively with registration errors less than 1mm. A paired t-test showed that the differences in registration error between AtamaiWarp and ANIMAL were significant (P ANIMAL, also provides more accurate results. From the second method, both algorithms treated the interior of homogeneous regions in an appropriate manner.

  13. Positional precision evaluation of 3 D laser scanner based on 3 D control field%基于三维控制场的三维激光扫描仪点位精度评定

    Institute of Scientific and Technical Information of China (English)

    史波; 郑敏

    2015-01-01

    为评定三维激光扫描仪的精度,设计了一个基于室内三维控制场的RIEGL VZ-400点位精度评定方案。通过实测得到其在距离10 m左右的外部、内部符合精度分别为±1.675 mm和±0.48 mm。详细介绍了室内全景三维控制场的布设、数据采集以及点位精度的评定方法。研究结果可为地面三维激光扫描仪的工程应用提供精度依据。%For evaluating the precision of a 3D laser scanner, we designed a positional precision evaluation solution for RIEGL VZ-400 on the basis of the 3D indoor panoramic control field. Through the evaluation, the precision of external and internal po-sition at distance of 10 m is ± 1. 675mm and ± 0. 48mm respectively. The layout, data collection way and the positional preci-sion evaluation method are introduced. The results could provide experiences and references for the application of ground 3D laser scanners.

  14. Research and Teaching: Methods for Creating and Evaluating 3D Tactile Images to Teach STEM Courses to the Visually Impaired

    Science.gov (United States)

    Hasper, Eric; Windhorst, Rogier; Hedgpeth, Terri; Van Tuyl, Leanne; Gonzales, Ashleigh; Martinez, Britta; Yu, Hongyu; Farkas, Zolton; Baluch, Debra P.

    2015-01-01

    Project 3D IMAGINE or 3D Image Arrays to Graphically Implement New Education is a pilot study that researches the effectiveness of incorporating 3D tactile images, which are critical for learning science, technology, engineering, and mathematics, into entry-level lab courses. The focus of this project is to increase the participation and…

  15. Configuration and Evaluation of a Dual-Doppler 3-D Wind Field System

    Science.gov (United States)

    Crawford, Winifred C.

    2014-01-01

    Current LSP, GSDO, and SLS space vehicle operations are halted when wind speeds from specific directions exceed defined thresholds and when lightning is a threat. Strong winds and lightning are difficult parameters for the 45th Weather Squadron (45 WS) to forecast, yet are important in the protection of customer vehicle operations and the personnel that conduct them. A display of the low-level horizontal wind field to reveal areas of high winds or convergence would be a valuable tool for forecasters in assessing the timing of high winds, or convection initiation and subsequent lightning occurrence. This is especially important for areas where no weather observation platforms exist. Developing a dual-Doppler radar capability would provide such a display to assist forecasters in predicting high winds and convection initiation. The wind fields can also be used to initialize a local mesoscale numerical weather prediction model to help improve the model forecast winds, convection initiation, and other phenomena. The 45 WS and NWS MLB tasked the Applied Meteorology Unit (AMU) to develop a dual- Doppler wind field display using data from the 45th Space Wing radar, known as the Weather Surveillance Radar (WSR), NWS MLB Weather Surveillance Radar 1988 Doppler (KMLB), and the Orlando International Airport Terminal Doppler Weather Radar (KMCO). They also stipulated that the software used should be freely available. The AMU evaluated two software packages and, with concurrence from NWS MLB and the 45 WS, chose the Warning Decision Support System-Integrated Information (WDSS-II). The AMU collected data from two significant weather cases: a tornadic event on 14 April 2013 and a severe wind and hail event on 12 February 2014. For the 14 April case, the data were from WSR and KMLB. For the 12 February case, the data were from KMCO and KMLB. The AMU installed WDSS-II on a Linux PC, then processed and quality controlled the radar data for display and analysis using WDSS-II tools

  16. Quantitative Evaluation of Tissue Surface Adaption of CAD-Designed and 3D Printed Wax Pattern of Maxillary Complete Denture

    Directory of Open Access Journals (Sweden)

    Hu Chen

    2015-01-01

    Full Text Available Objective. To quantitatively evaluate the tissue surface adaption of a maxillary complete denture wax pattern produced by CAD and 3DP. Methods. A standard edentulous maxilla plaster cast model was used, for which a wax pattern of complete denture was designed using CAD software developed in our previous study and printed using a 3D wax printer, while another wax pattern was manufactured by the traditional manual method. The cast model and the two wax patterns were scanned in the 3D scanner as “DataModel,” “DataWaxRP,” and “DataWaxManual.” After setting each wax pattern on the plaster cast, the whole model was scanned for registration. After registration, the deviations of tissue surface between “DataModel” and “DataWaxRP” and between “DataModel” and “DataWaxManual” were measured. The data was analyzed by paired t-test. Results. For both wax patterns produced by the CAD&RP method and the manual method, scanning data of tissue surface and cast surface showed a good fit in the majority. No statistically significant (P>0.05 difference was observed between the CAD&RP method and the manual method. Conclusions. Wax pattern of maxillary complete denture produced by the CAD&3DP method is comparable with traditional manual method in the adaption to the edentulous cast model.

  17. Extraction of 3D Femur Neck Trabecular Bone Architecture from Clinical CT Images in Osteoporotic Evaluation: a Novel Framework.

    Science.gov (United States)

    Sapthagirivasan, V; Anburajan, M; Janarthanam, S

    2015-08-01

    The early detection of osteoporosis risk enhances the lifespan and quality of life of an individual. A reasonable in-vivo assessment of trabecular bone strength at the proximal femur helps to evaluate the fracture risk and henceforth, to understand the associated structural dynamics on occurrence of osteoporosis. The main aim of our study was to develop a framework to automatically determine the trabecular bone strength from clinical femur CT images and thereby to estimate its correlation with BMD. All the 50 studied south Indian female subjects aged 30 to 80 years underwent CT and DXA measurements at right femur region. Initially, the original CT slices were intensified and active contour model was utilised for the extraction of the neck region. After processing through a novel process called trabecular enrichment approach (TEA), the three dimensional (3D) trabecular features were extracted. The extracted 3D trabecular features, such as volume fraction (VF), solidity of delta points (SDP) and boundness, demonstrated a significant correlation with femoral neck bone mineral density (r = 0.551, r = 0.432, r = 0.552 respectively) at p TEA method would be useful for spotting women vulnerable to osteoporotic risk.

  18. Failure Progress of 3D Reinforced GFRP Laminate during Static Bending, Evaluated by Means of Acoustic Emission and Vibrations Analysis

    Directory of Open Access Journals (Sweden)

    Mateusz Koziol

    2015-12-01

    Full Text Available The work aimed to assess the failure progress in a glass fiber-reinforced polymer laminate with a 3D-woven and (as a comparison plain-woven reinforcement, during static bending, using acoustic emission signals. The innovative method of the separation of the signal coming from the fiber fracture and the one coming from the matrix fracture with the use of the acoustic event’s energy as a criterion was applied. The failure progress during static bending was alternatively analyzed by evaluation of the vibration signal. It gave a possibility to validate the results of the acoustic emission. Acoustic emission, as well as vibration signal analysis proved to be good and effective tools for the registration of failure effects in composite laminates. Vibration analysis is more complicated methodologically, yet it is more precise. The failure progress of the 3D laminate is “safer” and more beneficial than that of the plain-woven laminate. It exhibits less rapid load capacity drops and a higher fiber effort contribution at the moment of the main laminate failure.

  19. FAT3D- An OECD/NEA benchmark on thermal fatigue in fluid mixing areas - CSNI integrity and ageing working group

    International Nuclear Information System (INIS)

    Thermal cycling is a widespread and recurring problem in nuclear power plants worldwide. Several incidents with leakage of primary water inside the containment challenged the integrity of nuclear power plants although no release outside of containment occurred. Thermal cycling was not taken into account at the design stage. Regulatory bodies, utilities and researchers have to address it for their operating plants. Thermal fatigue in a fluid mixing area is a well-known phenomenon that has already been studied in the past. Generally, this phenomenon is linked to turbulent mixing of two fluids at two different temperatures and creates 'elephant skin' type damage at the inner surface of the component and some cracks, which remain relatively small, compared to the thickness of the structure. However, this kind of fatigue damage can create cracks that propagate through the entire wall thickness. Some experts consider that 3D thermo-mechanical loading is a major factor influencing crack propagation through the thickness. This factor is linked to the complex thermal hydraulic loading and has an impact on the stress distribution in the structure and the damage or crack propagation estimates. For this reason an R and D program, based on a test and numerical interpretations, was launched by IRSN and conducted by CEA to quantify experimentally the influence of the 3D aspects on crack initiation and propagation. The main objective was to work on a configuration with a 3D thermal load easy enough to reproduce using numerical simulations, so that accurate mechanical studies could be carried out and assessment methodologies be validated or modified. Under the auspices of the OECD/NEA Committee for the Safety of Nuclear Installations (CSNI) and its Working Group on Integrity of Components and Structures (IAGE), a benchmark was launched in 2002. Seven organisations from four countries contributed to this effort aiming at comparing different approaches used for mechanical assessment

  20. LMFBR thermal-striping evaluation

    International Nuclear Information System (INIS)

    Thermal striping is defined as the fluctuating temperature field that is imposed on a structure when fluid streams at different temperatures mix in the vicinity of the structure surface. Because of the uncertainty in structural damage in LMFBR structures subject to thermal striping, EPRI has funded an effort for the Rockwell International Energy Systems Group to evaluate this problem. This interim report presents the following information: (1) a Thermal Striping Program Plan which identifies areas of analytic and experimental needs and presents a program of specific tasks to define damage experienced by ordinary materials of construction and to evaluate conservatism in the existing approach; (2) a description of the Thermal Striping Test Facility and its operation; and (3) results from the preliminary phase of testing to characterize the fluid environment to be applied in subsequent thermal striping damage experiments

  1. Evaluating integration of inland bathymetry in the U.S. Geological Survey 3D Elevation Program, 2014

    Science.gov (United States)

    Miller-Corbett, Cynthia

    2016-09-01

    Inland bathymetry survey collections, survey data types, features, sources, availability, and the effort required to integrate inland bathymetric data into the U.S. Geological Survey 3D Elevation Program are assessed to help determine the feasibility of integrating three-dimensional water feature elevation data into The National Map. Available data from wading, acoustic, light detection and ranging, and combined technique surveys are provided by the U.S. Geological Survey, National Oceanic and Atmospheric Administration, U.S. Army Corps of Engineers, and other sources. Inland bathymetric data accessed through Web-hosted resources or contacts provide useful baseline parameters for evaluating survey types and techniques used for collection and processing, and serve as a basis for comparing survey methods and the quality of results. Historically, boat-mounted acoustic surveys have provided most inland bathymetry data. Light detection and ranging techniques that are beneficial in areas hard to reach by boat, that can collect dense data in shallow water to provide comprehensive coverage, and that can be cost effective for surveying large areas with good water clarity are becoming more common; however, optimal conditions and techniques for collecting and processing light detection and ranging inland bathymetry surveys are not yet well defined.Assessment of site condition parameters important for understanding inland bathymetry survey issues and results, and an evaluation of existing inland bathymetry survey coverage are proposed as steps to develop criteria for implementing a useful and successful inland bathymetry survey plan in the 3D Elevation Program. These survey parameters would also serve as input for an inland bathymetry survey data baseline. Integration and interpolation techniques are important factors to consider in developing a robust plan; however, available survey data are usually in a triangulated irregular network format or other format compatible with

  2. Evaluation of effect of 3D video glasses on perceived pain and unpleasantness induced by restorative dental treatment

    DEFF Research Database (Denmark)

    Bentsen, Bo; Svensson, Peter; Wenzel, Ann

    2001-01-01

    -49 years) with a need for an occlusal dental restoration in two homologous teeth participated in the study, In this split-mouth design, the patient received the dental treatment wearing 3D video glasses and without video glasses (control situation) in a randomized order. The tooth cavities were prepared...... and control situation were tested by Student's t-test. There was no statistically significant effect on the perceived pain (p = 0.90) or unpleasantness (p = 0.39), but the majority (74%) of the patients would still prefer to wear video glasses if they were to have another dental filling, and 73% had expected......Previous studies on modulation of anxiety, pain and unpleasantness have documented a positive effect of video glasses (I-Glasses(TM), Virtual i-O(TM), Seattle, USA) on the perceived pain and unpleasantness under different laboratory and clinical conditions. The aim of this study was to evaluate...

  3. Construction method and application of 3D velocity model for evaluation of strong seismic motion and its cost performance

    International Nuclear Information System (INIS)

    Based on experiences of making subsurface structure models for seismic strong motion evaluation, the advantages and disadvantages in terms of convenience and cost for several methods used to make such models were reported. As for the details, gravity and micro-tremor surveys were considered to be highly valid in terms of convenience and cost. However, stratigraphy and seismic velocity structure are required to make accurate 3-D subsurface structures. To realize these, methods for directly examining subsurface ground or using controlled tremor sources (at high cost) are needed. As a result, it was summarized that in modeling subsurface structures, some sort of plan including both types of methods is desirable and that several methods must be combined to match one's intended purposes and budget. (authors)

  4. Evaluating integration of inland bathymetry in the U.S. Geological Survey 3D Elevation Program, 2014

    Science.gov (United States)

    Miller-Corbett, Cynthia

    2016-01-01

    Inland bathymetry survey collections, survey data types, features, sources, availability, and the effort required to integrate inland bathymetric data into the U.S. Geological Survey 3D Elevation Program are assessed to help determine the feasibility of integrating three-dimensional water feature elevation data into The National Map. Available data from wading, acoustic, light detection and ranging, and combined technique surveys are provided by the U.S. Geological Survey, National Oceanic and Atmospheric Administration, U.S. Army Corps of Engineers, and other sources. Inland bathymetric data accessed through Web-hosted resources or contacts provide useful baseline parameters for evaluating survey types and techniques used for collection and processing, and serve as a basis for comparing survey methods and the quality of results. Historically, boat-mounted acoustic surveys have provided most inland bathymetry data. Light detection and ranging techniques that are beneficial in areas hard to reach by boat, that can collect dense data in shallow water to provide comprehensive coverage, and that can be cost effective for surveying large areas with good water clarity are becoming more common; however, optimal conditions and techniques for collecting and processing light detection and ranging inland bathymetry surveys are not yet well defined.Assessment of site condition parameters important for understanding inland bathymetry survey issues and results, and an evaluation of existing inland bathymetry survey coverage are proposed as steps to develop criteria for implementing a useful and successful inland bathymetry survey plan in the 3D Elevation Program. These survey parameters would also serve as input for an inland bathymetry survey data baseline. Integration and interpolation techniques are important factors to consider in developing a robust plan; however, available survey data are usually in a triangulated irregular network format or other format compatible with

  5. Rheological variations across an active rift system -- results from lithosphere-scale 3D gravity and thermal models of the Kenya Rift

    Science.gov (United States)

    Meeßen, Christian; Sippel, Judith; Cacace, Mauro; Scheck-Wenderoth, Magdalena; Fishwick, Stewart; Heine, Christian; Strecker, Manfred R.

    2015-04-01

    Due to its tectono-volcanic activity and economic (geothermal and petroleum) potential, the eastern branch of the East African Rift System (EARS) is one of the best studied extensional systems worldwide and an important natural laboratory for the development of geodynamic concepts on rifting and nascent continental break-up. The Kenya Rift, an integral part of the eastern branch of the EARS, has formed in the area of weak Proterozoic crust of the Mozambique mobile belt adjacent to the rheologically stronger Archean Tanzania craton. To assess the variations in lithospheric strength between different tectonic domains and their influence on the tectonic evolution of the region, we developed a set of structural, density, thermal and rheological 3D models. For these models we integrated multi-disciplinary information, such as published geological field data, sediment thicknesses, well information, existing structural models, seismic refraction and reflection data, seismic tomography, gravity and heat-flow data. Our main approach focused on combined 3D isostatic and gravity modelling. The resulting lithosphere-scale 3D density model provides new insights into the depth distribution of the crust-mantle boundary and thickness variations of different crustal density domains. The latter further facilitate interpretations of variations of lithologies and related physical rock properties. By considering lithology-dependent heat production and thermal conductivity, we calculate the conductive thermal field across the region of the greater Kenya Rift. Finally, the assessed variations in lithology and temperature allow deriving differences in the integrated strength of the lithosphere across the different tectonic domains.

  6. On the Analysis and Evaluation of Direct Containment Heating with the Multidimensional Multiphase Flow Code MC3D

    Directory of Open Access Journals (Sweden)

    Renaud Meignen

    2010-01-01

    Full Text Available In the course of a postulated severe accident in an NPP, Direct Containment Heating (DCH may occur after an eventual failure of the vessel. DCH is related to dynamical, thermal, and chemical phenomena involved by the eventual fine fragmentation and dispersal of the corium melt out of the vessel pit. It may threaten the integrity of the containment by pressurization of its atmosphere. Several simplified modellings have been proposed in the past but they require a very strong fitting which renders any extrapolation regarding geometry, material, and scales rather doubtful. With the development of multidimensional multiphase flow computer codes, it is now possible to investigate the phenomenon numerically with more details. We present an analysis of the potential of the MC3D code to support the analysis of this phenomenon, restricting our discussion to the dynamical processes. The analysis is applied to the case of French 1300 MWe PWR reactors for which we derive a correlation for the corium dispersal rate for application in a Probabilistic Safety Analysis (PSA level 2 study.

  7. Probabilistic thermal-mechanical fatigue criterion for lost foam casting aluminium alloys based on 2D/3D porosities distribution

    Directory of Open Access Journals (Sweden)

    Szmytka F.

    2014-06-01

    Full Text Available A thermal-mechanical fatigue criterion is proposed to assess the lifetime of aluminium alloys produced by a lost foam casting process. It is based on the observed size distribution of pores sizes which are considered as critical zones for cracks initiation and gives reliable results when both pores sizes are identified from X-ray tomography and mean stresses are taken into account. Lifetime probabilities are finally successfully compared with experimental results.

  8. The Role and Practice of Property Optimisation to Help Evaluate 3D Geological Models using Gravity and Magnetic Data

    Science.gov (United States)

    Lane, R.

    2008-12-01

    As the shift from 2D to 3D geological mapping gathers strength and the number of multi-component potential field data sets increases, there is a need for greater sophistication in the gravity and magnetic modelling tools that can be used to help evaluate and refine the properties and geometry of the various units within these models. The hitherto standard approach of 2D forward modelling of selected cross-sections is progressively giving way to full 3D forward modelling. An example of a user-guided optimisation method to streamline what would otherwise be a time-consuming and frustrating manual iterative refinement process in 3D is presented. A combination of the density and magnetic properties assigned to each geological unit is derived such that the total calculated response best matches the supplied scalar, vector or tensor gravity and magnetic field observations, subject to specified levels of uncertainty (bounds) in the properties. Numerical optimisation is achieved with a standard linear least squares routine, subject to equality and bounds constraints. The user is presented with 3 standard options for every property, allowing the property values to be either (a) fixed, (b) free to vary within a specified range, or (c) free vary over a very broad range. Additionally, properties for a group of geological units can be linked so that they all return the same value. The parameterisation of density properties is relatively straight forward with a single property for each geological unit. Magnetic properties present more of a challenge. Three distinct scenarios are identified and a separate option can be selected for each geological unit. These assume (1) only induced susceptibility, (2) a combination of induced susceptibility and remanent magnetisation of know direction, or (3) a combination of induced susceptibility and remanent magnetisation of unknown direction. In this latter case, a solution is obtained for the total effective magnetisation in the form of 3

  9. Evaluation of the Heading Confinement Pressure Effect on Ground Settlement for EPBTBM Using Full 3D Numerical Analysis

    Directory of Open Access Journals (Sweden)

    Amir Hossein Haghi

    2013-06-01

    Full Text Available Ground settlement is often the most serious concern when tunneling under an old city with numerous historic monuments. A successful engineering design under these conditions would require getting the most out of the ground strength parameters and avoiding any weakening maneuver throughout the operation. Knowing that surface settlement is highly affected by tunneling parameters in EPB shield tunneling lead us to estimate the optimum values for the machine heading pressure with the lower amount of the ground settlement in fragile structure of the old city for the Esfahan Subway Project. Tunnels were dug underneath some of the most prominent historical sites along the path of the project. To improve precision and efficiency in tunneling operation, at the first step, tunnel heading confinement pressure is calculated by using an advanced 3D mathematical approach based on the limit equilibrium theory. Then, a promoted 3D finite element model is developed, taking into account the tunneling procedures and the designed heading confinement pressure from the first step. Settlements were pre-calculated and the surface displacement was checked at all sensitive locations. At the third step, settlement is estimated by exerting executed face supporting pressure to the tunnel face and the concluded amounts for displacement are compared with the outputs of extensometers. This comparison leads us to check the reliability of calculated settlements and the accuracy of the designed tunnel heading confinement pressure. Furthermore, evaluating the relation between extensometer outputs and executed tunnel face pressure at the points of extensometers stations validates the assumption that the safe face supporting pressure causes least surface displacement. Although the minimum pressure occurred in short term fluctuations, this approach confirms the sensibility of settlement with the least executed face supporting pressure.. It is also found that higher executed face

  10. Modelling of the steady state thermal behaviour of a permanent magnet direct current motor with commutator. 3D finite elements study

    Science.gov (United States)

    Bernard, R.; Glises, R.; Chamagne, D.; Cuchet, D.; Kauffmann, J. M.

    1999-08-01

    The aim of this work concerns the development and the validation of a thermal steady state model applied to a permanent magnet direct current motor with commutator. The rated power of the machine is 120 W. Design has been realized thanks to the thermal modulus of the computation software with the finite element method Flux3D. It is shown in this work how it is possible to use only the heat equation to simulate the thermal behaviour of the motor. It implies calculating of new fluid conductivities (considering also all thermal modes) by comparison of calculated and experimental temperatures. To realize these 3D modelizations, it is necessary to know and to locate all the losses of the motor which are considered as thermal sources. The experimental temperatures are given by 40 chromel-alumel thermocouples of 100 μm diameter located in the rotor and the stator of the machine. Numerical computations use Dirichlet boundary layer conditions given by an IR camera. Ce travail concerne le développement et la validation d'un modèle de simulation du comportement thermique tridimensionnel en régime permanent d'un moteur électrique de 120 watt à courant continu, à aimants permanents et à collecteur. Le logiciel est développé à partir du code de calculs par éléments finis Flux3D. L'équation de la chaleur modélise l'ensemble des transferts thermiques du moteur. Cela nécessite de recaler certains paramètres fluides par comparaison des températures simulées et expérimentales. Une séparation détaillée des différentes pertes est nécessaire pour obtenir une bonne précision finale. Un banc d'essais thermiques permet d'obtenir à l'aide de 40 thermocouples (chromel-alumel de 100 μm de diamètre) les températures au stator et au rotor. Une caméra thermographique infrarouge donne les conditions aux limites de Dirichlet nécessaires à la modélisation.

  11. IMRT 与3D-CRT 治疗胸部食管癌的剂量学评价∗%The Dosiology Evaluation of IMRT vs.3D-CRT for Thoracic Esophageal Cancer

    Institute of Scientific and Technical Information of China (English)

    刘锐锋; 张秋宁; 魏世鸿; 罗宏涛; 王小虎; 魏玺义

    2015-01-01

    Objective: To evaluate the dosimetry superiority of IMRT compared with 3D-CRT for thoracic esopha-geal cancer. Methods: Thirty patients with thoracic esophageal cancer who accepted radical radiotherapy in our hospital were included in this study. Varian Ecelipse treatment planing system was used to devise IMRT and 3D-CRT treatment plan. The target region of esophageal cancer was delineated according to target volume delineating principles of different segments. The prescription dose of IMRT were 51Gy/ 30F in CTV and 66Gy/ 30F in GTV, 50Gy/ 25F in CTV and 66Gy/33F in GTV for 3D-CRT. Main dosimetry parameters included target region dose and percentage by volume dose of OAR. Results: No significant difference was found in GTVmean and V10 when comparing IMRT with 3D-CRT, while the CTVmean, MLD, V30,V20 of lung , V40, V30 of heart, Dmax of spinal cord in IMRT were lower than those of 3D-CRT respectively with significant difference. V5 of lung in IMRT and 3D-CRT were 60. 9 ± 19. 2 and 53. 9 ± 12. 8 respectively with significant difference(P = 0. 004). Comparing the IMRT planning for middle-lower segment esophageal cancer with that for upper segment esophageal cancer, there was no statistical difference in GTVmean and CTVmean, while MLD , V30, V20, V10, V5 of lung, V40 ,V30 of heart for upper segment esophageal cancer were significantly lower than those of middle-lower segment esophageal cancer. Conclusion: IMRT is superior to 3D-CRT in dose distribution, especially for upper esophageal cancer. IMRT can obviously reduce Dmax and MLD of spinal cord,and percentage by volume dose of more than 10Gy for lung. While for V5 of lung, IMRT is higher than 3D-CRT.%目的::比较分析调强放疗(IMRT)和三维适形放疗(3D-CRT)计划在胸段食管癌治疗中的剂量学优劣。方法:选择我院行根治性放疗的胸段食管癌30例进行研究,根据不同部位进行亚组分析,瓦里安 Eclipse 计划系统制定放疗计划,按照不同部位食管癌的靶

  12. Spatial and Temporal Variability in the Circulation and Thermal Evolution of the Mantle in Subduction Zones: Insights From 3-D Laboratory Experiments.

    Science.gov (United States)

    Kincaid, C.; Griffiths, R. W.

    2003-12-01

    The subduction of oceanic lithosphere plays a key role in plate tectonics, the thermal evolution of the mantle and recycling processes between Earth's interior and surface. The majority of subduction models are two-dimensional (2-D), assuming limited variability in the direction parallel to the trench. Observationally based models increasingly appeal to three-dimensional (3-D) flow associated with trench migration and the sinking of oceanic plates with a translational component of motion (rollback). We report results from laboratory experiments that reveal fundamental differences in 3-D mantle circulation and temperature structure in response to subduction with and without a rollback component. In our experiments the upper mantle is simulated with glucose syrup and the subducting plate is represented with a Phenolic sheet that is forced to sink into the glucose along prescribed trajectories. An array of 40 thermisters embedded within the plate is used to monitor slab surface temperatures (SSTs). We vary the relative magnitude of downdip and translational components of slab motion and also consider cases where the plate steepens with time. Another parameter is the initial thickness of the thermal boundary layer (TBL) beneath the overriding plate. Without rollback motion, flow in the mantle wedge is sluggish, there is no mass flux around the plate, and plate edges heat up faster than plate centers. Rollback subduction drives flow around and beneath the sinking plate, velocities increase within the mantle wedge and are focussed towards the center of the plate and the surface of the plate heats more along the centerline. In addition to lateral variability in flow and mantle temperatures, results highlight temporal variability in SSTs and 3-D mantle flow trajectories associated with the initiation of subduction and variations between periods of predominantly downdip versus rollback sinking.

  13. Breas MRI: early experience with a 3-D fat-suppressed gradient echo sequence in the evaluation of breast lesion

    International Nuclear Information System (INIS)

    The early clinical experience with a 3-Dimensional Fourier Transform Gradient Echo sequence with fat suppression in the evaluation of breast masses is reported. Ten female patients with breast malignancies were pre-operatively evaluated with this sequence and the results compared with the pathological specimens. The scanning protocol included a noncontrast sequence followed by an immediate post-contrast sequence (completed 4.5min after intravenous contrast injection) and a delayed sequence. Images were assessed for maximum lesion and parenchymal enhancement, lesion size and additional enhancing abnormalities. In six patients, malignant masses enhanced maximally on the immediate postcontrast sequence with parenchyma enhancing maximally on delayed images. In three cases, there was preferential enhancement of malignant lesions over normal parenchyma but to a similar degree on both post-contrast sequences. In one case, both the lesion and parenchyma enhanced maximally on the delayed sequence. Magnetic resonance assessed lesion size accurately and also detected satellite malignancies in one case. However, lesion grade, associated in situ carcinoma and lymphovascular invasion did not impact on lesion enhancement. In this small series, a contrast-enhanced, fat-suppressed 3-D Gradient Echo Sequence detected breast carcinoma with high sensitivity. 16 refs., 2 tabs., 5 figs

  14. Constraints on the Lost City Hydrothermal System from borehole thermal data; 3-D models of heat flow and hydrothermal circulation in an oceanic core complex.

    Science.gov (United States)

    Titarenko, S.; McCaig, A. M.

    2014-12-01

    A perennial problem in near-ridge hydrothermal circulation is that the only directly measurable data to test models is often vent fluid temperature. Surface heat flow measurements may be available but without the underlying thermal structure it is not known if they are transient and affected by local hydrothermal flow, or conductive. The Atlantis Massif oceanic core complex at 30 °N on the mid-Atlantic Ridge, offers a unique opportunity to better constrain hydrothermal circulation models. The temperature profile in gabbroic rocks of IODP Hole 1309D was measured in IODPExpedition 340T, and found to be near-conductive, but with a slight inflexion at ~750 mbsf indicating downward advection of fluid above that level. The lack of deep convection is especially remarkable given that the long-lived Lost City Hydrothermal Field (LCHF) is located only 5km to the south. We have modelled hydrothermal circulation in the Massif using Comsol Multiphysics, comparing 2-D and 3-D topographic models and using temperature-dependent conductivity to give the best estimate of heatflow into the Massif. We can constrain maximum permeability in gabbro below 750 mbsf to 5e-17 m2. The thermal gradient in the upper part of the borehole can be matched with a permeability of 3e-14 m2 in a 750 m thick layer parallel to the surface of the massif, with upflow occurring in areas of high topography and downflow at the location of the borehole. However in 3-D the precise flow pattern is quite model dependent, and the thermal structure can be matched either by downflow centred on the borehole at lower permeability or centred a few hundred metres from the borehole at higher permeability. The borehole gradient is compatible with the longevity (>120 kyr) and outflow temperature (40-90 °C) of the LCHF either with a deep more permeable (1e-14 m2 to 1e-15 m2) domain beneath the vent site in 2-D or a permeable fault slot 500 to 1000m wide and parallel to the transform fault in 3-D. In both cases topography

  15. 3D computed tomographic evaluation of the upper airway space of patients undergoing mandibular distraction osteogenesis for micrognathia.

    Science.gov (United States)

    Bianchi, A; Betti, E; Badiali, G; Ricotta, F; Marchetti, C; Tarsitano, A

    2015-10-01

    Mandibular distraction osteogenesis (MDO) is currently an accepted method of treatment for patients requiring reconstruction of hypoplastic mandibles. To date one of the unsolved problems is how to assess the quantitative increase of mandible length needed to achieve a significant change in the volume of the posterior airway space (PAS) in children with mandibular micrognathia following distraction osteogenesis. The purpose of this study is to present quantitative volumetric evaluation of PAS in young patients having distraction osteogenesis for micrognathia using 3D-CT data sets and compare it with pre-operative situation. In this observational retrospective study, we report our experience in five consecutive patients who underwent MDO in an attempt to relieve severe upper airway obstruction. Each patient was evaluated before treatment (T0) and at the end of distraction procedure (T1) with computer tomography (CT) in axial, coronal, and sagittal planes and three-dimensional CT of the facial bones and upper airway. Using parameters to extract only data within anatomic constraints, a digital set of the edited upper airway volume was obtained. The volume determination was used for volumetric qualification of upper airway. The computed tomographic digital data were used to evaluate the upper airway volumes both pre-distraction and post-distraction. The mean length of distraction was 23 mm. Quantitative assessment of upper airway volume before and after distraction demonstrated increased volumes ranging from 84% to 3,087% with a mean of 536%. In conclusion, our study seems to show that DO can significantly increase the volume of the PAS in patients with upper airway obstruction following micrognathia, by an average of 5 times. Furthermore, the worse is the starting volume, the greater the increase in PAS to equal distraction.

  16. Measuring QoS in Web-Based Virtual Worlds : an evaluation of Unity 3D web builds

    OpenAIRE

    Bakri, Hussein; Allison, Colin

    2016-01-01

    Web Based Virtual Worlds (WBVW) provide users with an immersive 3D experience through their regular browser. They can be seen as prototypes for the 3D Web. This paper uses key Quality of Service metrics to compare and present measurements of two major formats for WBVW – Unity Web Player and WebGL. Significantly, in terms of realizing the 3D Web, the former requires a plug-in whereas the latter is now directly supported by major browsers. Metrics include Frames per Second, Frame Time, CPU usag...

  17. CAD/CAM-designed 3D-printed electroanalytical cell for the evaluation of nanostructured gas-diffusion electrodes

    Science.gov (United States)

    Chervin, Christopher N.; Parker, Joseph F.; Nelson, Eric S.; Rolison, Debra R.; Long, Jeffrey W.

    2016-04-01

    The ability to effectively screen and validate gas-diffusion electrodes is critical to the development of next-generation metal-air batteries and regenerative fuel cells. The limiting electrode in a classic two-terminal device such as a battery or fuel cell is difficult to discern without an internal reference electrode, but the flooded electrolyte characteristic of three-electrode electroanalytical cells negates the prime function of an air electrode—a void volume freely accessible to gases. The nanostructured catalysts that drive the energy-conversion reactions (e.g., oxygen reduction and evolution in the air electrode of metal-air batteries) are best evaluated in the electrode structure as-used in the practical device. We have designed, 3D-printed, and characterized an air-breathing, thermodynamically referenced electroanalytical cell that allows us to mimic the Janus arrangement of the gas-diffusion electrode in a metal-air cell: one face freely exposed to gases, the other wetted by electrolyte.

  18. A 3D reconstruction method of the body envelope from biplanar X-rays: Evaluation of its accuracy and reliability.

    Science.gov (United States)

    Nérot, Agathe; Choisne, Julie; Amabile, Célia; Travert, Christophe; Pillet, Hélène; Wang, Xuguang; Skalli, Wafa

    2015-12-16

    The aim of this study was to propose a novel method for reconstructing the external body envelope from the low dose biplanar X-rays of a person. The 3D body envelope was obtained by deforming a template to match the surface profiles in two X-rays images in three successive steps: global morphing to adopt the position of a person and scale the template׳s body segments, followed by a gross deformation and a fine deformation using two sets of pre-defined control points. To evaluate the method, a biplanar X-ray acquisition was obtained from head to foot for 12 volunteers in a standing posture. Up to 172 radio-opaque skin markers were attached to the body surface and used as reference positions. Each envelope was reconstructed three times by three operators. Results showed a bias lower than 7mm and a confidence interval (95%) of reproducibility lower than 6mm for all body parts, comparable to other existing methods matching a template onto stereographic photographs. The proposed method offers the possibility of reconstructing body shape in addition to the skeleton using a low dose biplanar X-rays system. PMID:26592437

  19. A 3D reconstruction method of the body envelope from biplanar X-rays: Evaluation of its accuracy and reliability.

    Science.gov (United States)

    Nérot, Agathe; Choisne, Julie; Amabile, Célia; Travert, Christophe; Pillet, Hélène; Wang, Xuguang; Skalli, Wafa

    2015-12-16

    The aim of this study was to propose a novel method for reconstructing the external body envelope from the low dose biplanar X-rays of a person. The 3D body envelope was obtained by deforming a template to match the surface profiles in two X-rays images in three successive steps: global morphing to adopt the position of a person and scale the template׳s body segments, followed by a gross deformation and a fine deformation using two sets of pre-defined control points. To evaluate the method, a biplanar X-ray acquisition was obtained from head to foot for 12 volunteers in a standing posture. Up to 172 radio-opaque skin markers were attached to the body surface and used as reference positions. Each envelope was reconstructed three times by three operators. Results showed a bias lower than 7mm and a confidence interval (95%) of reproducibility lower than 6mm for all body parts, comparable to other existing methods matching a template onto stereographic photographs. The proposed method offers the possibility of reconstructing body shape in addition to the skeleton using a low dose biplanar X-rays system.

  20. Measurements and ALE3D Simulations for Violence in a Scaled Thermal Explosion Experiment with LX-10 and AerMet 100 Steel

    Energy Technology Data Exchange (ETDEWEB)

    McClelland, M A; Maienschein, J L; Yoh, J J; deHaven, M R; Strand, O T

    2005-06-03

    We completed a Scaled Thermal Explosion Experiment (STEX) and performed ALE3D simulations for the HMX-based explosive, LX-10, confined in an AerMet 100 (iron-cobalt-nickel alloy) vessel. The explosive was heated at 1 C/h until cookoff at 182 C using a controlled temperature profile. During the explosion, the expansion of the tube and fragment velocities were measured with strain gauges, Photonic-Doppler-Velocimeters (PDVs), and micropower radar units. These results were combined to produce a single curve describing 15 cm of tube wall motion. A majority of the metal fragments were captured and cataloged. A fragment size distribution was constructed, and a typical fragment had a length scale of 2 cm. Based on these results, the explosion was considered to be a violent deflagration. ALE3D models for chemical, thermal, and mechanical behavior were developed for the heating and explosive processes. A four-step chemical kinetics model is employed for the HMX while a one-step model is used for the Viton. A pressure-dependent deflagration model is employed during the expansion. The mechanical behavior of the solid constituents is represented by a Steinberg-Guinan model while polynomial and gamma-law expressions are used for the equation of state of the solid and gas species, respectively. A gamma-law model is employed for the air in gaps, and a mixed material model is used for the interface between air and explosive. A Johnson-Cook model with an empirical rule for failure strain is used to describe fracture behavior. Parameters for the kinetics model were specified using measurements of the One-Dimensional-Time-to-Explosion (ODTX), while measurements for burn rate were employed to determine parameters in the burn front model. The ALE3D models provide good predictions for the thermal behavior and time to explosion, but the predicted wall expansion curve is higher than the measured curve. Possible contributions to this discrepancy include inaccuracies in the chemical models

  1. Non-destructive assay employing 2D and 3D digital radiographic imaging acquired with thermal neutrons and reactor-produced radioisotopes

    International Nuclear Information System (INIS)

    The inner structure of some objects can only be visualized by using suitable techniques, when safety reasons or expensive costs preclude the application of invasive procedures. The kind of agent rendering an object partially transparent, unveiling thus its features, depends upon the object size and composition. As a rough rule of thumb, light materials are transparent to gamma and X-rays while the heavy ones are transparent to neutrons. When, after traversing an object, they hit a proper 2-D detector, a radiograph is produced representing a convoluted cross section, called projection, of that object. Taking a large number of such projections for different object attitudes, it is possible to obtain a 3-D tomography of the object as a map of attenuation coefficients. This procedure however, besides a time-consuming task, requires specially tailored equipment and software, not always available or affordable. Yet, in some circumstances it is feasible to replace the 3-D tomography by a stereoscopy, allowing one to visualize the spatial configuration of the object under analysis. In this work, 2-D and 3-D radiographic images have been acquired using thermal neutrons and reactor-produced radioisotopes and proper imaging plates as detectors. The stereographic vision has been achieved by taking two radiographs of the same object at different angles, from the detector point of view. After a treatment to render them red-white and green-white they were properly merged to yield a single image capable to be watched with red-green glasses. All the image treatment and rendering has been performed with the software ImageJ. (author)

  2. Uncertainty and sensitivity analyses of the Kozloduy pump trip test using coupled thermal-hydraulic 3D kinetics code

    Energy Technology Data Exchange (ETDEWEB)

    Salah, Anis Bousbia [Facolta di Ingegneria, DIMNP, Universita di Pisa (Italy)]. E-mail: b.salah@ing.unipi.it; Kliem, Soeren [Forschungszentrum Rossendorf (FZR) (Germany); Rohde, Ulrich [Forschungszentrum Rossendorf (FZR) (Germany); D' Auria, Francesco [Facolta di Ingegneria, DIMNP, Universita di Pisa (Italy); Petruzzi, Alessandro [Facolta di Ingegneria, DIMNP, Universita di Pisa (Italy)

    2006-06-15

    The modeling of complex transients in nuclear power plants (NPP) remains a challenging topic for best estimate three-dimensional coupled code computational tools. This technique is, nowadays, extensively used since it allows decreasing conservatism in the calculation models and performs more realistic simulation and more precise consideration of multidimensional effects under complex transients in NPPs. Therefore, large international activities are in progress aiming to assess the capabilities of coupled codes and the new frontiers for the nuclear technology that could be opened by this technique. In the current paper, a contribution to the assessment and validation of coupled code technique through the Kozloduy VVER100 pump trip test is performed. For this purpose, the coupled RELAP5/3.3-PARCS/2.6 code is used. The code results were assessed against experimental data. Deviations between code predictions and measurements are mainly due to the used models for evaluating and modeling of the Doppler feedback effect. Further investigations through the use of two 'antagonist' uncertainty GRS and the CIAU methods, were considered in order to evaluate and quantify the origin of the observed discrepancies. It was revealed on one hand that relative error quantification discrepancies exist between the two approaches, and further enhancements for both methods are needed.

  3. Studies of a new class of high electro-thermal performing Polyimide embedded with 3D scaffold in the harsh environment of outer space

    Science.gov (United States)

    Loeblein, Manuela; Bolker, Asaf; Tsang, Siu Hon; Atar, Nurit; Uzan-Saguy, Cecile; Verker, Ronen; Gouzman, Irina; Grossman, Eitan; Teo, Edwin Hang Tong

    The polymer class of Polyimides (PIs) has been wide-spread in the use of outer space coatings due to their chemical stability and flexibility. Nevertheless, their poor thermal conductivity and completely electrically insulating characteristics have caused severe limitations, such as thermal management challenges and spacecraft electrostatic charging, which forces the use of additional materials such as brittle ITO in order to completely resist the harsh environment of space. For this reason, we developed a new composite material via infiltration of PI with a 3D scaffold which improves PIs performance and resilience and enables the use of only a single flexible material to protect spacecraft. Here we present a study of this new material based on outer-space environment simulated on ground. It includes an exhaustive range of tests simulating space environments in accordance with European Cooperation for Space Standard (ECSS), which includes atomic oxygen (AO) etching, Gamma-ray exposure and outgassing properties over extended periods of time and under strenuous mechanical bending and thermal annealing cycles. Measurement methods for the harsh environment of space and the obtained results will be presented.

  4. 3D Animation Essentials

    CERN Document Server

    Beane, Andy

    2012-01-01

    The essential fundamentals of 3D animation for aspiring 3D artists 3D is everywhere--video games, movie and television special effects, mobile devices, etc. Many aspiring artists and animators have grown up with 3D and computers, and naturally gravitate to this field as their area of interest. Bringing a blend of studio and classroom experience to offer you thorough coverage of the 3D animation industry, this must-have book shows you what it takes to create compelling and realistic 3D imagery. Serves as the first step to understanding the language of 3D and computer graphics (CG)Covers 3D anim

  5. 3D video

    CERN Document Server

    Lucas, Laurent; Loscos, Céline

    2013-01-01

    While 3D vision has existed for many years, the use of 3D cameras and video-based modeling by the film industry has induced an explosion of interest for 3D acquisition technology, 3D content and 3D displays. As such, 3D video has become one of the new technology trends of this century.The chapters in this book cover a large spectrum of areas connected to 3D video, which are presented both theoretically and technologically, while taking into account both physiological and perceptual aspects. Stepping away from traditional 3D vision, the authors, all currently involved in these areas, provide th

  6. A study of different approaches for multi-scale sensitivity analysis of the TALL-3D experiment using thermal-hydraulic computer codes

    International Nuclear Information System (INIS)

    In the context of the FP7 European THINS Project, complex thermal-hydraulic phenomena relevant for the Generation IV of nuclear reactors are investigated. KTH (Sweden) built the TALL-3D facility to investigate the transition from forced to natural circulation of the Lead-Bismuth Eutectic (LBE) in a pool connected to a 3-leg primary circuit with two heaters and a heat exchanger. The simulation of such 3D phenomena is a challenging task. GRS (Germany) developed the coupling between the Computational Fluid Dynamics (CFD) code ANSYS CFX and the System Analysis code ATHLET. Such coupled codes combine the advantages of CFD, which allow a fine resolution of 3D phenomena, and of System Analysis codes, which are fast running. TUM (Germany) is responsible for the Uncertainty and Sensitivity Analysis of the coupled ATHLET-CFX model in the THINS Project. The influence of modeling uncertainty on simulation results needs to be assessed to characterize and to improve the model and, eventually, to assess its performance against experimental data. TUM has developed a computational framework capable of propagating model input uncertainty through coupled codes. This framework can also be used to apply different approaches for the assessment of the influence of the uncertain input parameters on the model output (Sensitivity Analysis). The work reported in this paper focuses on three methods for the assessment of the sensitivity of the results to the modeling uncertainty. The first method (Morris) allows for the computation of the Elementary Effects resulting from the input parameters. This method is widely used to perform Screening Analysis. The second method (Spearman's rank correlation) relies on regression-based non-parametric measures. This method is suitable if the relation between the input and the output variables is at least monotonic, with the advantage of a low computational cost. The last method (Sobol') computes so-called total effect indices which account for

  7. Evaluation of the relationship between renal function and renal volume-vascular indices using 3D power Doppler ultrasound

    Energy Technology Data Exchange (ETDEWEB)

    Cansu, Aysegul, E-mail: drcansu@gmail.com; Kupeli, Ali; Kul, Sibel; Eyuboglu, Ilker; Oguz, Sukru; Ozturk, Mehmet Halil; Dinc, Hasan

    2014-07-15

    Purpose: To investigate the relationship between renal function and total renal volume-vascular indices using 3D power Doppler ultrasound (3DPDUS). Materials and methods: One hundred six patients with hypertensive proteinuric nephropathy (HPN) (49 male, 57 female) and 65 healthy controls (32 male, 33 female) were evaluated prospectively using 3DPDUS. Total renal volume (RV), vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using Virtual Organ Computer-aided Analysis (VOCAL). The estimated glomerular filtration rates (GFRs) of the patients with HPN and the control group were calculated. The patients with HPN were divided into two groups on the basis of GFR, normal (≥90) or reduced (<90). Differences between groups were compared using ANOVA. Correlations between GFR, renal volume and vascular indices were analyzed using Pearson's correlation analysis. Significance was set at p < 0.05. Results: The mean total RV, VI, FI and VFI values in the reduced GFR, normal GFR and control groups were RV (ml): 234.7, 280.7 and 294.6; VI: 17.6, 27.6 and 46.8; FI: 79.1, 88.7 and 93.9 and VFI: 7.1, 12.7 and 23.8. There were statistically significant differences between the groups (p < 0.001). Total RVs and vascular indices exhibited significant correlations with estimated GFR (r = 0.53–0.59, p < 0.001) Conclusion: Three-dimensional power Doppler ultrasound is a reliable predictive technique in renal function analysis.

  8. Global left ventricular function in cardiac CT. Evaluation of an automated 3D region-growing segmentation algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Muehlenbruch, Georg; Das, Marco; Hohl, Christian; Wildberger, Joachim E.; Guenther, Rolf W.; Mahnken, Andreas H. [University Hospital (RWTH) Aachen, Department of Diagnostic Radiology, Aachen (Germany); Rinck, Daniel; Flohr, Thomas G. [Siemens Medical Solutions, Forchheim (Germany); Koos, Ralf; Knackstedt, Christian [University Hospital (RWTH) Aachen, Department of Cardiology, Aachen (Germany)

    2006-05-15

    The purpose was to evaluate a new semi-automated 3D region-growing segmentation algorithm for functional analysis of the left ventricle in multislice CT (MSCT) of the heart. Twenty patients underwent contrast-enhanced MSCT of the heart (collimation 16 x 0.75 mm; 120 kV; 550 mAseff). Multiphase image reconstructions with 1-mm axial slices and 8-mm short-axis slices were performed. Left ventricular volume measurements (end-diastolic volume, end-systolic volume, ejection fraction and stroke volume) from manually drawn endocardial contours in the short axis slices were compared to semi-automated region-growing segmentation of the left ventricle from the 1-mm axial slices. The post-processing-time for both methods was recorded. Applying the new region-growing algorithm in 13/20 patients (65%), proper segmentation of the left ventricle was feasible. In these patients, the signal-to-noise ratio was higher than in the remaining patients (3.2{+-}1.0 vs. 2.6{+-}0.6). Volume measurements of both segmentation algorithms showed an excellent correlation (all P{<=}0.0001); the limits of agreement for the ejection fraction were 2.3{+-}8.3 ml. In the patients with proper segmentation the mean post-processing time using the region-growing algorithm was diminished by 44.2%. On the basis of a good contrast-enhanced data set, a left ventricular volume analysis using the new semi-automated region-growing segmentation algorithm is technically feasible, accurate and more time-effective. (orig.)

  9. Evaluation of accuracy of 3D reconstruction images using multi-detector CT and cone-beam CT

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mi Ja [Graduate School of Clinical Dentistry, Hallym University, Seoul (Korea, Republic of); Huh, Kyung Hoe; Yi, Won Jin; Heo, Min Suk; Lee, Sam Sun; Choi, Soon Chul [School of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    2012-03-15

    This study was performed to determine the accuracy of linear measurements on three-dimensional (3D) images using multi-detector computed tomography (MDCT) and cone-beam computed tomography (CBCT). MDCT and CBCT were performed using 24 dry skulls. Twenty-one measurements were taken on the dry skulls using digital caliper. Both types of CT data were imported into OnDemand software and identification of landmarks on the 3D surface rendering images and calculation of linear measurements were performed. Reproducibility of the measurements was assessed using repeated measures ANOVA and ICC, and the measurements were statistically compared using a Student t-test. All assessments under the direct measurement and image-based measurements on the 3D CT surface rendering images using MDCT and CBCT showed no statistically difference under the ICC examination. The measurements showed no differences between the direct measurements of dry skull and the image-based measurements on the 3D CT surface rendering images (P>.05). Three-dimensional reconstructed surface rendering images using MDCT and CBCT would be appropriate for 3D measurements.

  10. Bending and Thermal Expansion Properties of 3D-Cf/SiC Composites%3D-Cf/SiC复合材料的弯曲强度及热膨胀性能分析

    Institute of Scientific and Technical Information of China (English)

    殷晓光; 马天; 李正操; 苗伟

    2010-01-01

    采用料浆浸渗和CVI工艺制备了含有ZrB2陶瓷颗粒的3D-Cf/SiC复合材料,对其进行弯曲强度和线热膨胀系数测试,通过扫描电镜观察复合材料的表面及断口形貌.结果表明,3D-Cf/SiC复合材料的弯曲强度为107.99 MPa,满足一般热防护材料的使用要求;其线热膨胀系数随温度变化的规律是由于碳纤维和SiC陶瓷基体之间线热膨胀系数的不匹配及热残余应力造成的.

  11. 3D joint inversion using seismic data and marine controlled-source electromagnetic data for evaluating gas hydrate concentrations

    Science.gov (United States)

    Kim, B.; Byun, J.; Seol, S. J.; Jeong, S.; Chung, Y.; Kwon, T.

    2015-12-01

    For many decades, gas hydrates have been received great attention as a potential source of natural gas. Therefore, the detailed information of structures of buried gas hydrates and their concentrations are prerequisite for the production for the gas hydrate as a reliable source of alternate energy. Recently, for this reason, a lot of gas hydrate assessment methods have been proposed by many researchers. However, it is still necessary to establish as new method for the further improvement of the accuracy of the 3D gas hydrate distribution. In this study, we present a 3D joint inversion method that provides superior quantitative information of gas hydrate distributions using 3D seismic data obtained by ocean-bottom cable (OBC) and marine controlled-source electromagnetic (CSEM) data. To verify our inversion method, we first built the general 3D gas hydrate model containing vertical methane-flow pathways. With the described model, we generated synthetic 3D OBC data and marine CSEM data using finite element modeling algorithms, respectively. In the joint inversion process, to obtain the high-resolution volumetric P-wave velocity structure, we applied the 3D full waveform inversion algorithm to the acquired OBC data. After that, the obtained P-wave velocity model is used as the structure constraint to compute cross-gradients with the updated resistivity model in the EM inversion process. Finally, petrophysical relations were applied to estimate volumetric gas hydrate concentrations. The proposed joint inversion process makes possible to obtain more precise quantitative gas hydrate assessment than inversion processes using only seismic or EM data. This technique can be helpful for accurate decision-making in gas hydrate development as well as in their production monitoring.

  12. Thermal effusivity measurement based on analysis of 3D heat flow by modulated spot heating using a phase lag matrix with a combination of thermal effusivity and volumetric heat capacity

    Science.gov (United States)

    Ohta, Hiromichi; Hatori, Kimihito; Matsui, Genzou; Yagi, Takashi; Miyake, Shugo; Okamura, Takeo; Endoh, Ryo; Okada, Ryo; Morishita, Keisuke; Yokoyama, Shinichiro; Taguchi, Kohei; Kato, Hideyuki

    2016-11-01

    The study goal was to establish a standard industrial procedure for the measurement of thermal effusivity by a thermal microscope (TM), using a periodic heating method with a thermoreflectance (TR) technique. To accomplish this goal, a working group was organized that included four research institutes. Each institute followed the same procedure: a molybdenum (Mo) film was sputtered on the surface of Pyrex, yttria-stabilized zirconia (YSZ), alumina (Al2O3), Germanium (Ge), and silicon (Si) samples, and then the phase lag of the laser intensity modulation was measured by the resultant surface temperature. A procedure was proposed to calibrate the effect of 3D heat flow, based on the analytical solution of the heat conduction equation, and thermal effusivity was measured. The derived values show good agreement with literature values. As a result, the TM calibration procedure can be recommended for practical use in measuring the thermal effusivity in a small region of the materials.

  13. MNSR transient analyses and thermal hydraulic safety margins for HEU and LEU cores using the RELAP5-3D code

    International Nuclear Information System (INIS)

    For safety analyses to support conversion of MNSR reactors from HEU fuel to LEU fuel, a RELAP5-3D model was set up to simulate the entire MNSR system. This model includes the core, the beryllium reflectors, the water in the tank and the water in the surrounding pool. The MCNP code was used to obtain the power distributions in the core and to obtain reactivity feedback coefficients for the transient analyses. The RELAP5-3D model was validated by comparing measured and calculated data for the NIRR-1 reactor in Nigeria. Comparisons include normal operation at constant power and a 3.77 mk rod withdrawal transient. Excellent agreement was obtained for core coolant inlet and outlet temperatures for operation at constant power, and for power level, coolant inlet temperature, and coolant outlet temperature for the rod withdrawal transient. In addition to the negative reactivity feedbacks from increasing core moderator and fuel temperatures, it was necessary to calculate and include positive reactivity feedback from temperature changes in the radial beryllium reflector and changes in the temperature and density of the water in the tank above the core and at the side of the core. The validated RELAP5-3D model was then used to analyze 3.77 mk rod withdrawal transients for LEU cores with two UO2 fuel pin designs. The impact of cracking of oxide LEU fuel is discussed. In addition, steady-state power operation at elevated power levels was evaluated to determine steady-state safety margins for onset of nucleate boiling and for onset of significant voiding. (author)

  14. 3D Skeleton model derived from Kinect Depth Sensor Camera and its application to walking style quality evaluations

    Directory of Open Access Journals (Sweden)

    Kohei Arai

    2013-07-01

    Full Text Available Feature extraction for gait recognition has been created widely. The ancestor for this task is divided into two parts, model based and free-model based. Model-based approaches obtain a set of static or dynamic skeleton parameters via modeling or tracking body components such as limbs, legs, arms and thighs. Model-free approaches focus on shapes of silhouettes or the entire movement of physical bodies. Model-free approaches are insensitive to the quality of silhouettes. Its advantage is a low computational costs comparing to model-based approaches. However, they are usually not robust to viewpoints and scale. Imaging technology also developed quickly this decades. Motion capture (mocap device integrated with motion sensor has an expensive price and can only be owned by big animation studio. Fortunately now already existed Kinect camera equipped with depth sensor image in the market with very low price compare to any mocap device. Of course the accuracy not as good as the expensive one, but using some preprocessing we can remove the jittery and noisy in the 3D skeleton points. Our proposed method is part of model based feature extraction and we call it 3D Skeleton model. 3D skeleton model for extracting gait itself is a new model style considering all the previous model is using 2D skeleton model. The advantages itself is getting accurate coordinate of 3D point for each skeleton model rather than only 2D point. We use Kinect to get the depth data. We use Ipisoft mocap software to extract 3d skeleton model from Kinect video. From the experimental results shows 86.36% correctly classified instances using SVM.

  15. Evaluation of a 3-D interactive tooth atlas by dental students in dental anatomy and endodontics courses.

    Science.gov (United States)

    Wright, Edward F; Hendricson, William D

    2010-02-01

    Advances in information and communication technology continually offer innovations to assist faculty in their efforts to help students learn new information or develop new skills. However, faculty members are often hesitant to incorporate these innovations into their courses out of fear that these new methods may not provide the anticipated outcomes. Hence, students are often the subjects of educational trials to evaluate curriculum innovations by comparing a new teaching/learning method to traditional lecture-based instruction. The most typical finding is that students can learn equally well by either method. However, two questions that have not been studied extensively in dental education are whether dental students will actually use computer-based educational resources made available to them and whether students perceive these materials to provide a value-added learning experience. Accordingly, the goals of this study were to determine whether first-year dental students (D1), second-year dental students (D2), and third-year dental students (D3) would 1) use an interactive tooth atlas, available on a DVD, as a study aid and 2) perceive that the atlas provided sufficient value-added benefit for their dental anatomy (D1), preclinical laboratory endodontics (D2), and clinical endodontics (D3) courses to recommend adding it to their school's comprehensive electronic resources. A low percentage of the students (14 percent; 40/289) voluntarily downloaded the atlas from a DVD to their laptops prior to the addition of incentives in the form of atlas-related examination questions. Even after incentives were added, only 43 percent of the students (126/289) downloaded the DVD. After using the atlas, students responded to the statement "Using the 3D Interactive Tooth Atlas was beneficial for me" on a 0 to 10 scale with 0 representing strongly disagree, 5 representing unsure, and 10 representing strongly agree. The mean rankings were 5.34 for D1s, 6.79 for D2s, and 7.28 for D

  16. Non-invasive 3d magnetic resonance thermal mapping: determination of the lesion size during laser-therapy in ex vivo tissues

    International Nuclear Information System (INIS)

    Developments in open magnetic resonance imaging (MRI) magnets have made possible the use of reproducible thermosensitive sequences to determine temperature distribution inside biological tissue. This study aimed to compare MR thermal mapping during laser-induced interstitial thermal therapy (LITT) with macroscopically observed thermal lesions in order to estimate the 3D size of the coagulative necrosis. Laser irradiation was performed ex vivo with a 980-nm laser in pig liver in an open low-magnetic field (0.2 T) scanner. Laser light was transmitted through a 1,040/600 μm (outer/core diameter) bare-tipped silica fiber. Laser energy was applied in a pulsed mode (10 s laser-on, 10 s laser-off) for 12 min, power 6 W, energy 2,160 J. Gradient-echo images acquired during laser irradiation were used for real-time temperature mapping by the MR-T1 method. The method was then validated by a comparison between calculated 60 C isotherm and macroscopic lesion size. Temperature accuracy was 2.2 C, temporal resolution was 20 s. and spatial resolution was 2.5 x 2.5 x 2.5 mm3 (0.8% of the mean volume of coagulative necrosis). The mean lesion volume was 1830 mm3 ± 189 (standard error), σ (standard deviation) = 499 and range (min = 1281; max = 2591) mm3. Volumes calculated from MRI isotherms were correlated (correlation coefficient r 2 = 0.70) significantly (P = 0.08) to lesion size determined from macroscopic measurements. Using fast gradient-echo sequence, laser monitoring is achieved efficiently with fast temperature mapping. T1-weighted images appear promising in monitoring lesion size evolution in future low magnetic field in vivo studies. (orig.)

  17. EUROPEANA AND 3D

    Directory of Open Access Journals (Sweden)

    D. Pletinckx

    2012-09-01

    Full Text Available The current 3D hype creates a lot of interest in 3D. People go to 3D movies, but are we ready to use 3D in our homes, in our offices, in our communication? Are we ready to deliver real 3D to a general public and use interactive 3D in a meaningful way to enjoy, learn, communicate? The CARARE project is realising this for the moment in the domain of monuments and archaeology, so that real 3D of archaeological sites and European monuments will be available to the general public by 2012. There are several aspects to this endeavour. First of all is the technical aspect of flawlessly delivering 3D content over all platforms and operating systems, without installing software. We have currently a working solution in PDF, but HTML5 will probably be the future. Secondly, there is still little knowledge on how to create 3D learning objects, 3D tourist information or 3D scholarly communication. We are still in a prototype phase when it comes to integrate 3D objects in physical or virtual museums. Nevertheless, Europeana has a tremendous potential as a multi-facetted virtual museum. Finally, 3D has a large potential to act as a hub of information, linking to related 2D imagery, texts, video, sound. We describe how to create such rich, explorable 3D objects that can be used intuitively by the generic Europeana user and what metadata is needed to support the semantic linking.

  18. Evaluation of grades 3 and 4 chondromalacia of the knee using T2*-weighted 3D gradient-echo articular cartilage imaging

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, B.J. [Dept. of Radiology, Univ. of Miami School of Medicine, FL (United States)

    2001-06-01

    Objective. To determine the accuracy of T2*-weighted three-dimensional (3D) gradient-echo articular cartilage imaging in the identification of grades 3 and 4 chondromalacia of the knee.Design and patients. A retrospective evaluation of 80 patients who underwent both arthroscopic and MRI evaluation was performed. The 3D images were interpreted by one observer without knowledge of the surgical results. The medial and lateral femoral condyles, the medial and lateral tibial plateau, the patellar cartilage and trochlear groove were evaluated. MR cartilage images were considered positive if focal reduction of cartilage thickness was present (grade 3 chondromalacia) or if complete loss of cartilage was present (grade 4 chondromalacia). Comparison of the 3D MR results with the arthroscopic findings was performed.Results. Eighty patients were included in the study group. A total of 480 articular cartilage sites were evaluated with MRI and arthroscopy. Results of MR identification of grades 3 and 4 chondromalacia, all sites combined, were: sensitivity 83%, specificity 97%, false negative rate 17%, false positive rate 3%, positive predictive value 87%, negative predictive value 95%, overall accuracy 93%.Conclusion. The results demonstrate that T2*-weighted 3D gradient-echo articular cartilage imaging can identify grades 3 and 4 chondromalacia of the knee. (orig.)

  19. Shaping 3-D boxes

    DEFF Research Database (Denmark)

    Stenholt, Rasmus; Madsen, Claus B.

    2011-01-01

    Enabling users to shape 3-D boxes in immersive virtual environments is a non-trivial problem. In this paper, a new family of techniques for creating rectangular boxes of arbitrary position, orientation, and size is presented and evaluated. These new techniques are based solely on position data......, making them different from typical, existing box shaping techniques. The basis of the proposed techniques is a new algorithm for constructing a full box from just three of its corners. The evaluation of the new techniques compares their precision and completion times in a 9 degree-of-freedom (Do......F) docking experiment against an existing technique, which requires the user to perform the rotation and scaling of the box explicitly. The precision of the users' box construction is evaluated by a novel error metric measuring the difference between two boxes. The results of the experiment strongly indicate...

  20. Solid works 3D

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Cheol Yeong

    2004-02-15

    This book explains modeling of solid works 3D and application of 3D CAD/CAM. The contents of this book are outline of modeling such as CAD and 2D and 3D, solid works composition, method of sketch, writing measurement fixing, selecting projection, choosing condition of restriction, practice of sketch, making parts, reforming parts, modeling 3D, revising 3D modeling, using pattern function, modeling necessaries, assembling, floor plan, 3D modeling method, practice floor plans for industrial engineer data aided manufacturing, processing of CAD/CAM interface.

  1. Solid works 3D

    International Nuclear Information System (INIS)

    This book explains modeling of solid works 3D and application of 3D CAD/CAM. The contents of this book are outline of modeling such as CAD and 2D and 3D, solid works composition, method of sketch, writing measurement fixing, selecting projection, choosing condition of restriction, practice of sketch, making parts, reforming parts, modeling 3D, revising 3D modeling, using pattern function, modeling necessaries, assembling, floor plan, 3D modeling method, practice floor plans for industrial engineer data aided manufacturing, processing of CAD/CAM interface.

  2. 磁共振3D-Tricks技术在评估舌动脉解剖中的应用%Anatomic evaluation of the lingual artery using magnetic resonance 3D-Tricks technique

    Institute of Scientific and Technical Information of China (English)

    王忠平; 李咏梅; 欧阳羽; 吕发金; 罗天友; 陈璇; 曾春; 侯焕新; 黄富洪

    2012-01-01

    Objective To evaluate the ability of three-dimensional time-resolved imaging of contrast kinetics (3D-Tricks) sequence for identifying the lingual artery with three-dimensional reformation technique. Methods Forty-three subjects without vascular disease of brain and neck (including 28 patients with suspected vertebrobasilar insufficiency and 15 patients who excluded metastatic brain tumor) underwent 3.0T MR scans using a 3D-Tricks sequence. Morphologic features of lingual artery were evaluated using the volume rendering (VR), multi-planar reformat (MPR) and maximum intensity projection (MIP) techniques. The distances of the origin of lingual artery from both the segment of the greater horn of hyoid bone and bifurcation of common carotid artery were measured. Results 86 lingual arteries were clearly displayed in forty-three subjects. The 58 lingual arteries directly originated from external carotid artery. 27 lingual arteries originated from the facial artery and only one arised from superior thyroid artery. The position between the lingual artery segment in the greater horn of hyoid bone and the greater hom of hyoid bone were relatively constant. 45 lingual arteries located in the superior to bifurcation of common carotid artery. 9 arteries ran forward in parallel with bifurcation of common carotid artery. 32 arteries located in the inferior to bifurcation of common carotid artery. The inner diameters of lingual artery from the origin of lingual artery were (2.88 ±0.46) mm. The distances of lingual artery from the bifurcation of common carotid artery to the segment of the greater hom of hyoid bone were (1.33±0.62) cm, (1.28±0.61) cm, respectively. Conclusions 3D-Tricks can clearly visualize the morphologic features of the lingual artery in vivo, which is a helpful instruction for clinical application.%目的 评价MR血管成像技术一三维时间分辨力对比剂动力成像(Three-dimenstional time-resolved imaging of contrast Kinetics,3D-Tricks)对舌

  3. Calcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model

    OpenAIRE

    Frandsen, Stine Krog; Gibot, Laure; Madi, Moinecha; Gehl, Julie; Rols, Marie-Pierre

    2015-01-01

    Background Calcium electroporation describes the use of high voltage electric pulses to introduce supraphysiological calcium concentrations into cells. This promising method is currently in clinical trial as an anti-cancer treatment. One very important issue is the relation between tumor cell kill efficacy–and normal cell sensitivity. Methods Using a 3D spheroid cell culture model we have tested the effect of calcium electroporation and electrochemotherapy using bleomycin on three different h...

  4. Graphic 3D ergonomic database in evaluation of virtual models of kitchen design/adaptation for needs of handicapped persons

    OpenAIRE

    Branowski, B.; Rychlik, M.; Sydor, M.; Zabłocki, M.

    2011-01-01

    The paper presents a concept for the utilisation of anthropometric and biomechanical graphic 3D database of a motorically handicapped person using a wheelchair for purposes of analysis and assessment of kitchen space design. Contemporary tendencies in kitchen design or adaptation for disabled persons or senior citizens were discussed. Methodological assumptions as well as a test station for measurements of reach of arms and forces for a male disabled person sitting in a wheelchair were presen...

  5. Microwave-Assisted Synthesis and Antimicrobial Evaluation of Novel Spiroisoquinoline and Spiropyrido[4,3-d]pyrimidine Derivatives

    Directory of Open Access Journals (Sweden)

    Rasha M. Faty

    2015-01-01

    Full Text Available Bromination of N-substituted homophthalimides and tetrahydropyrido[4,3-d]- pyrimidine-5,7-diones produces 4,4-dibromohomophthalimide and 8,8-dibromo-tetrahydropyrido[4,3-d]pyrimidine-5,7-dione derivatives, respectively, that can be used as precursors for spiro derivatives. The dibromo derivatives react with different binucleophilic reagents to produce several spiroisoquinoline and spirotetrahydropyrido[4,3-d]- pyrimidine-5,7-dione derivatives, respectively. Reaction of the dibromo derivatives with malononitrile produces dicyanomethylene derivatives which react with different binucleophiles to produce new spiro derivatives. All new compounds are prepared by using the usual chemical conditions and microwave assisted conditions. The latter conditions improved the reaction yields, reduced reaction times and ameliorated the effects on the surrounding environment as the reactions are carried out in closed systems. Structures of the newly synthesized compounds are proved using spectroscopic methods such as IR, MS, 1H-NMR and 13C-NMR and elemental analyses. Some of the newly synthesized compounds were tested for their antimicrobial activities, whereby four of them showed moderate activities and the rest showed low or no activities towards the investigated species.

  6. The value of 3D T1-weighted gradient-echo MR imaging for evaluation of the appendix during pregnancy: preliminary results

    International Nuclear Information System (INIS)

    Background The use of oral contrast has been essential for the identification of a normal appendix on MR imaging during pregnancy. However, stool could be used as a positive oral contrast as it is characterized by a relatively high signal on T1-weighted imaging, and 3D T1-weighted gradient-echo (T1W-GRE) MR imaging has been used to evaluate 3 mm diameter intestines in fetuses. Purpose To evaluate the added value of 3D T1W-GRE MR imaging in combination with T2-weighted imaging (T2WI) compared to T2WI alone for evaluating the appendix during pregnancy. Material and Methods Eighteen consecutive pregnant patients who were clinically suspected of having acute appendicitis underwent appendix MR imaging which included T2WI with or without spectral presaturation attenuated inversion-recovery (SPAIR) fat suppression, and 3D T1W-GRE with SPAIR fat suppression. Two radiologists reviewed the two image sets (the T2WI set and the combined set of T2WI and 3D T1W-GRE images). Pathologic and clinical results served as the reference standard. The differences in the degree of visibility of the appendix and confidence scale for diagnosing acute appendicitis between two image sets were compared by using the paired Wilcoxon signed rank test. Results For both reviewers, the degree of visibility of the appendix using the combined T2WI and 3D T1W-GRE images was significantly higher than using T2WI alone (P < 0.01), and the confidence levels for acute appendicitis using combined T2WI and 3D T1W-GRE images were significantly different from those using T2WI alone (P < 0.01). In the 13 patients with a normal appendix, both reviewers showed improved confidence levels for appendicitis using combined T2WI and 3D T1W-GRE images than T2WI alone. Conclusion Adding 3D T1W-GRE images to T2WI is helpful for identification of the appendix, as compared to T2WI alone in pregnant women without ingestion of oral contrast material. This may improve diagnostic confidence for acute appendicitis in pregnant

  7. The value of 3D T1-weighted gradient-echo MR imaging for evaluation of the appendix during pregnancy: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Kyung Mi; Kim, Seong Hyun; Choi, Dongil; Lee, Soon Jin; Rhim, Hyunchul; Park, Min Jung (Depts. of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), email: kshyun@skku.edu

    2011-10-15

    Background The use of oral contrast has been essential for the identification of a normal appendix on MR imaging during pregnancy. However, stool could be used as a positive oral contrast as it is characterized by a relatively high signal on T1-weighted imaging, and 3D T1-weighted gradient-echo (T1W-GRE) MR imaging has been used to evaluate 3 mm diameter intestines in fetuses. Purpose To evaluate the added value of 3D T1W-GRE MR imaging in combination with T2-weighted imaging (T2WI) compared to T2WI alone for evaluating the appendix during pregnancy. Material and Methods Eighteen consecutive pregnant patients who were clinically suspected of having acute appendicitis underwent appendix MR imaging which included T2WI with or without spectral presaturation attenuated inversion-recovery (SPAIR) fat suppression, and 3D T1W-GRE with SPAIR fat suppression. Two radiologists reviewed the two image sets (the T2WI set and the combined set of T2WI and 3D T1W-GRE images). Pathologic and clinical results served as the reference standard. The differences in the degree of visibility of the appendix and confidence scale for diagnosing acute appendicitis between two image sets were compared by using the paired Wilcoxon signed rank test. Results For both reviewers, the degree of visibility of the appendix using the combined T2WI and 3D T1W-GRE images was significantly higher than using T2WI alone (P < 0.01), and the confidence levels for acute appendicitis using combined T2WI and 3D T1W-GRE images were significantly different from those using T2WI alone (P < 0.01). In the 13 patients with a normal appendix, both reviewers showed improved confidence levels for appendicitis using combined T2WI and 3D T1W-GRE images than T2WI alone. Conclusion Adding 3D T1W-GRE images to T2WI is helpful for identification of the appendix, as compared to T2WI alone in pregnant women without ingestion of oral contrast material. This may improve diagnostic confidence for acute appendicitis in pregnant

  8. 3-D multi-observable probabilistic inversion for the compositional and thermal structure of the lithosphere and upper mantle. II: General methodology and resolution analysis

    Science.gov (United States)

    Afonso, J. C.; Fullea, J.; Yang, Y.; Connolly, J. A. D.; Jones, A. G.

    2013-04-01

    Here we present a 3-D multi-observable probabilistic inversion method, particularly designed for high-resolution (regional) thermal and compositional mapping of the lithosphere and sub-lithospheric upper mantle that circumvents the problems associated with traditional inversion methods. The key aspects of the method are as follows: (a) it exploits the increasing amount and quality of geophysical datasets; (b) it combines multiple geophysical observables (Rayleigh and Love dispersion curves, body-wave tomography, magnetotelluric, geothermal, petrological, gravity, elevation, and geoid) with different sensitivities to deep/shallow, thermal/compositional anomalies into a single thermodynamic-geophysical framework; (c) it uses a general probabilistic (Bayesian) formulation to appraise the data; (d) no initial model is needed; (e) compositional a priori information relies on robust statistical analyses of a large database of natural mantle samples; and (f) it provides a natural platform to estimate realistic uncertainties. In addition, the modular nature of the method/algorithm allows for incorporating or isolating specific forward operators according to available data. The strengths and limitations of the method are thoroughly explored with synthetic models. It is shown that the a posteriori probability density function (i.e., solution to the inverse problem) satisfactorily captures spatial variations in bulk composition and temperature with high resolution, as well as sharp discontinuities in these fields. Our results indicate that only temperature anomalies of ΔT ⪆150°C and large compositional anomalies of ΔMg# > 3 (or bulk ΔAl2O3 > 1.5) can be expected to be resolved simultaneously when combining high-quality geophysical data. This resolving power is sufficient to explore some long-standing problems regarding the nature and evolution of the lithosphere (e.g., vertical stratification of cratonic mantle, compositional versus temperature signatures in seismic

  9. Analyses of Instability Events in the Peach Bottom-2 BWR Using Thermal-Hydraulic and 3D Neutron Kinetic Coupled Codes Technique

    Directory of Open Access Journals (Sweden)

    Antonella Lombardi Costa

    2008-01-01

    Full Text Available Boiling water reactor (BWR instabilities may occur when, starting from a stable operating condition, changes in system parameters bring the reactor towards an unstable region. In order to design more stable and safer core configurations, experimental and theoretical studies about BWR stability have been performed to characterise the phenomenon and to predict the conditions for its occurrence. In this work, contributions to the study of BWR instability phenomena are presented. The RELAP5/MOD3.3 thermal-hydraulic (TH system code and the PARCS-2.4 3D neutron kinetic (NK code were coupled to simulate BWR transients. Different algorithms were used to calculate the decay ratio (DR and the natural frequency (NF from the power oscillation predicted by the transient calculations as two typical parameters used to provide a quantitative description of instabilities. The validation of the code model set up for the Peach Bottom Unit 2 BWR plant is performed against low-flow stability tests (LFSTs. The four series of LFST have been performed during the first quarter of 1977 at the end of cycle 2 in Pennsylvania. The tests were intended to measure the reactor core stability margins at the limiting conditions used in design and safety analyses.

  10. 3d-3d correspondence revisited

    Science.gov (United States)

    Chung, Hee-Joong; Dimofte, Tudor; Gukov, Sergei; Sułkowski, Piotr

    2016-04-01

    In fivebrane compactifications on 3-manifolds, we point out the importance of all flat connections in the proper definition of the effective 3d {N}=2 theory. The Lagrangians of some theories with the desired properties can be constructed with the help of homological knot invariants that categorify colored Jones polynomials. Higgsing the full 3d theories constructed this way recovers theories found previously by Dimofte-Gaiotto-Gukov. We also consider the cutting and gluing of 3-manifolds along smooth boundaries and the role played by all flat connections in this operation.

  11. Automatic segmentation and 3D reconstruction of intravascular ultrasound images for a fast preliminar evaluation of vessel pathologies.

    Science.gov (United States)

    Sanz-Requena, Roberto; Moratal, David; García-Sánchez, Diego Ramón; Bodí, Vicente; Rieta, José Joaquín; Sanchis, Juan Manuel

    2007-03-01

    Intravascular ultrasound (IVUS) imaging is used along with X-ray coronary angiography to detect vessel pathologies. Manual analysis of IVUS images is slow and time-consuming and it is not feasible for clinical purposes. A semi-automated method is proposed to generate 3D reconstructions from IVUS video sequences, so that a fast diagnose can be easily done, quantifying plaque length and severity as well as plaque volume of the vessels under study. The methodology described in this work has four steps: a pre-processing of IVUS images, a segmentation of media-adventitia contour, a detection of intima and plaque and a 3D reconstruction of the vessel. Preprocessing is intended to remove noise from the images without blurring the edges. Segmentation of media-adventitia contour is achieved using active contours (snakes). In particular, we use the gradient vector flow (GVF) as external force for the snakes. The detection of lumen border is obtained taking into account gray-level information of the inner part of the previously detected contours. A knowledge-based approach is used to determine which level of gray corresponds statistically to the different regions of interest: intima, plaque and lumen. The catheter region is automatically discarded. An estimate of plaque type is also given. Finally, 3D reconstruction of all detected regions is made. The suitability of this methodology has been verified for the analysis and visualization of plaque length, stenosis severity, automatic detection of the most problematic regions, calculus of plaque volumes and a preliminary estimation of plaque type obtaining for automatic measures of lumen and vessel area an average error smaller than 1mm(2) (equivalent aproximately to 10% of the average measure), for calculus of plaque and lumen volume errors smaller than 0.5mm(3) (equivalent approximately to 20% of the average measure) and for plaque type estimates a mismatch of less than 8% in the analysed frames. PMID:17215103

  12. Development of a 3D finite element model evaluating air-coupled ultrasonic measurements of nonlinear Rayleigh waves

    Science.gov (United States)

    Uhrig, Matthias P.; Kim, Jin-Yeon; Jacobs, Laurence J.

    2016-02-01

    This research presents a 3D numerical finite element (FE) model which, previously developed, precisely simulates non-contact, air-coupled measurements of nonlinear Rayleigh wave propagation. The commercial FE-solver ABAQUS is used to perform the simulations. First, frequency dependent pressure wave attenuation is investigated numerically to reconstruct the sound pressure distribution along the active surface of the non-contact receiver. Second, constitutive law and excitation source properties are optimized to match nonlinear ultrasonic experimental data. Finally, the FE-model data are fit with analytical solutions showing a good agreement and thus, indicating the significance of the study performed.

  13. IZDELAVA TISKALNIKA 3D

    OpenAIRE

    Brdnik, Lovro

    2015-01-01

    Diplomsko delo analizira trenutno stanje 3D tiskalnikov na trgu. Prikazan je razvoj in principi delovanja 3D tiskalnikov. Predstavljeni so tipi 3D tiskalnikov, njihove prednosti in slabosti. Podrobneje je predstavljena zgradba in delovanje koračnih motorjev. Opravljene so meritve koračnih motorjev. Opisana je programska oprema za rokovanje s 3D tiskalniki in komponente, ki jih potrebujemo za izdelavo. Diploma se oklepa vprašanja, ali je izdelava 3D tiskalnika bolj ekonomična kot pa naložba v ...

  14. A procedure for the evaluation of 2D radiographic texture analysis to assess 3D bone micro-architecture; Evaluation de l'analyse de la texture de radiographies 2D pour evaluer les micro architecture 3D d'os

    Energy Technology Data Exchange (ETDEWEB)

    Apostol, L.; Peyrin, F.; Yot, S.; Basset, O.; Odet, Ch. [CREATIS - Centre National de la Recherche Scientifique (UMR CNRS 5515), 69 - Villeurbanne (France); Apostal, L.; Boller, E. [European Synchrotron Radiation Facility (ESRF), 38 - Grenoble (France); Tabary, J.; Dinten, J.M. [CEA Grenoble, Lab. d' Electronique et de Technologie de l' Informatique (LETI), 38 (France); Boudousq, V.; Kotzki, P.O. [Faculte de Medecine, Lab. de Biophysique Medicale, 30 - Nimes (France)

    2004-07-01

    Although the diagnosis of osteoporosis is mainly based on Dual X-ray Absorptiometry, it has been shown that trabecular bone micro-architecture is also an important factor in regards of fracture risk, which can be efficiently assessed in vitro using three-dimensional x-ray microtomography ({mu}CT). In vivo, techniques based on high-resolution x-ray radiography associated to texture analysis have been proposed to investigate bone micro-architecture, but their relevance for giving pertinent 3D information is unclear. The purpose of this work was to develop a method for evaluating the relationships between 3D micro-architecture and 2D texture parameters, and optimizing the conditions for radiographic imaging. Bone sample images taken from cortical to cortical were acquired using 3D-synchrotron x-ray {mu}CT at the ESRF. The 3D digital images were further used for two purposes: 1) quantification of three-dimensional bone micro-architecture, 2) simulation of realistic x-ray radiographs under different acquisition conditions. Texture analysis was then applied to these 2D radiographs using a large variety of methods (co-occurrence, spectrum, fractal...). First results of the statistical analysis between 2D and 3D parameters allowed identifying the most relevant 2D texture parameters. (authors)

  15. Physics-based Simulation of Human Posture Using 3D Whole Body Scanning Technology for Astronaut Space Suit Evaluation

    Science.gov (United States)

    Kim, Kyu-Jung

    2005-01-01

    Over the past few years high precision three-dimensional (3D) full body laser scanners have been developed to be used as a powerful anthropometry tool for quantification of the morphology of the human body. The full body scanner can quickly extract body characteristics in non-contact fashion. It is required for the Anthropometry and Biomechanics Facility (ABF) to have capabilities for kinematics simulation of a digital human at various postures whereas the laser scanner only allows capturing a single static posture at each time. During this summer fellowship period a theoretical study has been conducted to estimate an arbitrary posture with a series of example postures through finite element (FE) approximation and found that four-point isoparametric FE approximation would result in reasonable maximum position errors less than 5%. Subsequent pilot scan experiments demonstrated that a bead marker with a nominal size of 6 mm could be used as a marker for digitizing 3-D coordinates of anatomical landmarks for further kinematic analysis. Two sessions of human subject testing were conducted for reconstruction of an arbitrary postures from a set of example postures for each joint motion for the forearm/hand complex and the whole upper extremity.

  16. Unassisted 3D camera calibration

    Science.gov (United States)

    Atanassov, Kalin; Ramachandra, Vikas; Nash, James; Goma, Sergio R.

    2012-03-01

    With the rapid growth of 3D technology, 3D image capture has become a critical part of the 3D feature set on mobile phones. 3D image quality is affected by the scene geometry as well as on-the-device processing. An automatic 3D system usually assumes known camera poses accomplished by factory calibration using a special chart. In real life settings, pose parameters estimated by factory calibration can be negatively impacted by movements of the lens barrel due to shaking, focusing, or camera drop. If any of these factors displaces the optical axes of either or both cameras, vertical disparity might exceed the maximum tolerable margin and the 3D user may experience eye strain or headaches. To make 3D capture more practical, one needs to consider unassisted (on arbitrary scenes) calibration. In this paper, we propose an algorithm that relies on detection and matching of keypoints between left and right images. Frames containing erroneous matches, along with frames with insufficiently rich keypoint constellations, are detected and discarded. Roll, pitch yaw , and scale differences between left and right frames are then estimated. The algorithm performance is evaluated in terms of the remaining vertical disparity as compared to the maximum tolerable vertical disparity.

  17. SLI Thermal Imaging Requirements Evaluation

    Science.gov (United States)

    Hoffman, E. H.; Woody, L. M.; Wirth, S. M.; Smith, D. S.

    2015-12-01

    The Landsat program has provided a continuous record of global terrestrial imagery since 1972. This data record is an invaluable resource for determining long term trends and monitoring rates of change in land usage, forest health, water quality, and glacier retreat. In 2014, the National Aeronautics and Space Administration (NASA), supported by the United States Geological Survey (USGS), initiated the sustainable land imaging (SLI) architecture study to develop an affordable system design for acquiring future terrestrial imagery compatible with the existing Landsat data record. The principal objective has been to leverage recent advances in focal plane technologies to enable smaller, lower-cost instruments and launch options. We present an evaluation of the trade space implied by the SLI thermal imaging requirements as well as the performance potential of enabling technologies. Multiple approaches, each incorporating measured performance data for state-of-the-art detectors, are investigated to simultaneously optimize instrument mass and volume, spatial response, radiometric sensitivity, and radiometric uncertainty.

  18. Preoperative evaluation of neurovascular relationship by using contrast-enhanced and unenhanced 3D time-of-flight MR angiography in patients with trigeminal neuralgia

    International Nuclear Information System (INIS)

    Background Microvascular decompression is an etiological strategy for the therapy of trigeminal neuralgia (TN). Preoperative identification of neurovascular compression, therefore, could have an impact on the determination of appropriate treatment for TN. Purpose To evaluate the value of contrast-enhanced and unenhanced three-dimensional (3D) time-of-flight (TOF) MR angiography in the visualization of neurovascular relationship in patients with TN. Material and Methods Thirty-seven patients with unilateral TN underwent unenhanced and contrast-enhanced 3D TOF MR angiography with a 3.0-T MR system. Images were reviewed by a radiologist blinded to clinical details. Vascular contact with the trigeminal nerve was identified, and the nature of the involved vessels (artery or vein) was determined. All patients underwent microvascular decompression. Results In 37 patients with TN, contrast-enhanced 3D TOF MR angiography identified surgically verified neurovascular contact in 35 of 36 symptomatic nerves, and there was no false-positive. Based on surgical findings, the sensitivity of MR imaging was 97.2% and specificity 100%. The nature of the offending vessel was correctly identified in 94.4% of the patients by using the combination of contrast-enhanced and unenhanced MR angiography. Conclusion Contrast-enhanced 3D TOF MR angiography is useful in the detection of vascular contact with the trigeminal nerve in patients with TN, and this MR imaging in combination with unenhanced MR angiography could help in the identification of the nature of the responsible vessels

  19. Preoperative evaluation of neurovascular relationship by using contrast-enhanced and unenhanced 3D time-of-flight MR angiography in patients with trigeminal neuralgia

    Energy Technology Data Exchange (ETDEWEB)

    Qin, Zhou; Zhiling, Liu; Chuanfu, Li; Qingshi Zeng (Dept. of Radiology, Qilu Hospital of Shandong Univ., Jinan (China)), email: zengqingshi@yahoo.cn; Chuncheng, Qu (Dept. of Neurosurgery, the Second Hospital of Shandong Univ., Jinan (China)); Shilei, Ni (Dept. of Neurosurgery, Qilu Hospital of Shandong Univ., Jinan (China))

    2011-10-15

    Background Microvascular decompression is an etiological strategy for the therapy of trigeminal neuralgia (TN). Preoperative identification of neurovascular compression, therefore, could have an impact on the determination of appropriate treatment for TN. Purpose To evaluate the value of contrast-enhanced and unenhanced three-dimensional (3D) time-of-flight (TOF) MR angiography in the visualization of neurovascular relationship in patients with TN. Material and Methods Thirty-seven patients with unilateral TN underwent unenhanced and contrast-enhanced 3D TOF MR angiography with a 3.0-T MR system. Images were reviewed by a radiologist blinded to clinical details. Vascular contact with the trigeminal nerve was identified, and the nature of the involved vessels (artery or vein) was determined. All patients underwent microvascular decompression. Results In 37 patients with TN, contrast-enhanced 3D TOF MR angiography identified surgically verified neurovascular contact in 35 of 36 symptomatic nerves, and there was no false-positive. Based on surgical findings, the sensitivity of MR imaging was 97.2% and specificity 100%. The nature of the offending vessel was correctly identified in 94.4% of the patients by using the combination of contrast-enhanced and unenhanced MR angiography. Conclusion Contrast-enhanced 3D TOF MR angiography is useful in the detection of vascular contact with the trigeminal nerve in patients with TN, and this MR imaging in combination with unenhanced MR angiography could help in the identification of the nature of the responsible vessels

  20. A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair

    Science.gov (United States)

    Holmes, Benjamin; Bulusu, Kartik; Plesniak, Michael; Zhang, Lijie Grace

    2016-02-01

    3D bioprinting has begun to show great promise in advancing the development of functional tissue/organ replacements. However, to realize the true potential of 3D bioprinted tissues for clinical use requires the fabrication of an interconnected and effective vascular network. Solving this challenge is critical, as human tissue relies on an adequate network of blood vessels to transport oxygen, nutrients, other chemicals, biological factors and waste, in and out of the tissue. Here, we have successfully designed and printed a series of novel 3D bone scaffolds with both bone formation supporting structures and highly interconnected 3D microvascular mimicking channels, for efficient and enhanced osteogenic bone regeneration as well as vascular cell growth. Using a chemical functionalization process, we have conjugated our samples with nano hydroxyapatite (nHA), for the creation of novel micro and nano featured devices for vascularized bone growth. We evaluated our scaffolds with mechanical testing, hydrodynamic measurements and in vitro human mesenchymal stem cell (hMSC) adhesion (4 h), proliferation (1, 3 and 5 d) and osteogenic differentiation (1, 2 and 3 weeks). These tests confirmed bone-like physical properties and vascular-like flow profiles, as well as demonstrated enhanced hMSC adhesion, proliferation and osteogenic differentiation. Additional in vitro experiments with human umbilical vein endothelial cells also demonstrated improved vascular cell growth, migration and organization on micro-nano featured scaffolds.

  1. SU-F-BRE-06: Evaluation of Patient CT Dose Reconstruction From 3D Diode Array Measurements Using Anthropomorphic Phantoms

    Energy Technology Data Exchange (ETDEWEB)

    Huang, M; Benhabib, S; Cardan, R; Brezovich, I; Popple, R [The University of Alabama at Birmingham, Birmingham, AL (United States); Faught, A; Followill, D [The University of Texas MD Anderson Cancer Center, Houston, TX (United States)

    2014-06-15

    Purpose: To compare 3D reconstructed dose of IMRT plans from 3D diode array measurements with measurements in anthropomorphic phantoms. Methods: Six IMRT plans were created for the IROC Houston (RPC) head and neck (H and N) and lung phantoms following IROC Houston planning protocols. The plans included flattened and unflattened beam energies ranging from 6 MV to 15 MV and both static and dynamic MLC tecH and Niques. Each plan was delivered three times to the respective anthropomorphic phantom, each of which contained thermoluminescent dosimeters (TLDs) and radiochromic films (RCFs). The plans were also delivered to a Delta4 diode array (Scandidos, Uppsala, Sweden). Irradiations were done using a TrueBeam STx (Varian Medical Systems, Palo Alto, CA). The dose in the patient was calculated by the Delta4 software, which used the diode measurements to estimate incident energy fluence and a kernel-based pencil beam algorithm to calculate dose. The 3D dose results were compared with the TLD and RCF measurements. Results: In the lung, the average difference between TLDs and Delta4 calculations was 5% (range 2%–7%). For the H and N, the average differences were 2.4% (range 0%–4.5%) and 1.1% (range 0%–2%) for the high- and low-dose targets, respectively, and 12% (range 10%-13%) for the organ-at-risk simulating the spinal cord. For the RCF and criteria of 7%/4mm, 5%/3mm, and 3%/3mm, the average gamma-index pass rates were 95.4%, 85.7%, and 76.1%, respectively for the H and N and 76.2%, 57.8%, and 49.5% for the lung. The pass-rate in the lung decreased with increasing beam energy, as expected for a pencil beam algorithm. Conclusion: The H and N phantom dose reconstruction met the IROC Houston acceptance criteria for clinical trials; however, the lung phantom dose did not, most likely due to the inaccuracy of the pencil beam algorithm in the presence of low-density inhomogeneities. Work supported by PHS grant CA10953 and CA81647 (NCI, DHHS)

  2. 3D and Education

    Science.gov (United States)

    Meulien Ohlmann, Odile

    2013-02-01

    Today the industry offers a chain of 3D products. Learning to "read" and to "create in 3D" becomes an issue of education of primary importance. 25 years professional experience in France, the United States and Germany, Odile Meulien set up a personal method of initiation to 3D creation that entails the spatial/temporal experience of the holographic visual. She will present some different tools and techniques used for this learning, their advantages and disadvantages, programs and issues of educational policies, constraints and expectations related to the development of new techniques for 3D imaging. Although the creation of display holograms is very much reduced compared to the creation of the 90ies, the holographic concept is spreading in all scientific, social, and artistic activities of our present time. She will also raise many questions: What means 3D? Is it communication? Is it perception? How the seeing and none seeing is interferes? What else has to be taken in consideration to communicate in 3D? How to handle the non visible relations of moving objects with subjects? Does this transform our model of exchange with others? What kind of interaction this has with our everyday life? Then come more practical questions: How to learn creating 3D visualization, to learn 3D grammar, 3D language, 3D thinking? What for? At what level? In which matter? for whom?

  3. The evaluation of 3D-CISS sequence in diagnosis of midbrain aqueduct obstruction%磁共振3D-CISS 序列在中脑导水管梗阻诊断中的应用

    Institute of Scientific and Technical Information of China (English)

    付汪星; 车英玉; 程敬亮

    2014-01-01

    目的:探讨磁共振3D-CISS 序列在中脑导水管梗阻诊断中的应用价值。方法利用3.0T 超导 MR 扫描仪对46例中脑导水管梗阻患者脑部进行 FLASH T1 WI、TSE T2 WI 和3D-CISS 序列扫描,并对3D-CISS 序列原始图像进行重建,观察3种序列对中脑导水管结构的显示情况,进行对比分析。结果 FLASH T1 WI、TSE T2 WI 及3D-CISS 序列对中脑导水管梗阻病变显示率分别为13%、71.7%、100%。3种序列两两对比均有显著差异(P <0.0167)。结论3D-CISS 序列在显示中脑导水管梗阻病变方面较常规序列存在优势。%Objective To explore the value of three-dimensional constructive inference in steady state sequence (3D-CISS se-quence)in case of midbrain aqueduct obstruction.Methods 46 cases with midbrain aqueduct obstruction were scanned with FLASH T1 WI、TSE T2 WI and 3D-CISS sequence at 3.0T superconductive MR scanner.The original images of the 3D-CISS sequence were reconstructed.The images of three sequences showing midbrain aqueduct obstruction were observed and analyzed.Results The de-tection rate of the midbrain aqueduct obstruction was 13% 、71.7% and 100% in FLASH T1 WI、TSE T2 WI and 3D-CISS sequence, respectively.The difference between the three sequences were significant (P <0.01 67).Conclusion 3D-CISS sequence shows mid-brain aqueduct obstruction more accurately.

  4. Evaluation of LOCA in a swimming-pool type reactor using the 3D-AIRLOCA code

    International Nuclear Information System (INIS)

    The 3D-AIRLOCA code was used to calculate core temperature evolution curves in the wake of a full LOCA in a swimming pool type reactor, resulting in complete core exposure and dryout within about 1000 sec of the initiating event. The results show that fuel integrity loss thresholds (450 C for softening and 650 C for melting) are reached and exceeded over large fractions of the core at powr levels as low as 2 MW. At 4.5 MW, the softening threshold is reached even when the accident occurs up to 12 hours after reactor shutdown for continuous operation, and up to 2 hrs after shutdown for intermittent (6 hrs/day, 4 days a week) operation. The situation is even more severe in blockage cases, when the air flow through the core is blocked by residual water at the grid plate level. It is concluded that substantial fission product releases are quite likely in this class of accidents. (orig.)

  5. Development, Calibration and Evaluation of a Portable and Direct Georeferenced Laser Scanning System for Kinematic 3D Mapping

    Science.gov (United States)

    Heinz, Erik; Eling, Christian; Wieland, Markus; Klingbeil, Lasse; Kuhlmann, Heiner

    2015-12-01

    In recent years, kinematic laser scanning has become increasingly popular because it offers many benefits compared to static laser scanning. The advantages include both saving of time in the georeferencing and a more favorable scanning geometry. Often mobile laser scanning systems are installed on wheeled platforms, which may not reach all parts of the object. Hence, there is an interest in the development of portable systems, which remain operational even in inaccessible areas. The development of such a portable laser scanning system is presented in this paper. It consists of a lightweight direct georeferencing unit for the position and attitude determination and a small low-cost 2D laser scanner. This setup provides advantages over existing portable systems that employ heavy and expensive 3D laser scanners in a profiling mode. A special emphasis is placed on the system calibration, i. e. the determination of the transformation between the coordinate frames of the direct georeferencing unit and the 2D laser scanner. To this end, a calibration field is used, which consists of differently orientated georeferenced planar surfaces, leading to estimates for the lever arms and boresight angles with an accuracy of mm and one-tenth of a degree. Finally, point clouds of the mobile laser scanning system are compared with georeferenced point clouds of a high-precision 3D laser scanner. Accordingly, the accuracy of the system is in the order of cm to dm. This is in good agreement with the expected accuracy, which has been derived from the error propagation of previously estimated variance components.

  6. Comprehensive evaluation of high-steep slope stability and optimal high-steep slope design by 3D physical modeling

    Institute of Scientific and Technical Information of China (English)

    Xing-ping Lai; Peng-fei Shan; Mei-feng Cai; Fen-hua Ren; Wen-hui Tan

    2015-01-01

    High-steep slope stability and its optimal excavation design in Shuichang open pit iron mine were analyzed based on a large 3D physical simulation technique. An optimal excavation scheme with a relatively steeper slope angle was successfully implemented at the northwest wall between Nos. 4 and 5 exploration lines of Shuichang Iron Mine, taking into account the 3D scale effect. The phys-ico-mechanical properties of rock materials were obtained by laboratory tests conducted on sample cores from exploration drilling directly from the iron mine. A porous rock-like composite material was formed for the model, and the mechanical parameters of the material were assessed experimentally;specifically, the effect of water on the sample was quantitatively determined. We adopted an experimental setup using stiff modular applied static loading to carry out a visual excavation of the slope at a random depth. The setup was equipped with acous-tic emission (AE) sensors, and the experiments were monitored by crack optical acquirement, ground penetrating radar, and close-field pho-togrammetry to investigate the mechanisms of rock-mass destabilization in the high-steep slope. For the complex study area, the model re-sults indicated a clear correlation between the model’s destabilization resulting from slope excavation and the collected monitoring informa-tion. During the model simulation, the overall angle of the slope increased by 1–6 degrees in different sections. Dramatically, the modeled excavation scheme saved over 80 million tons of rock from extraction, generating enormous economic and ecological benefits.

  7. Design and Evaluation of a Fiber-Optic Grip Force Sensor with Compliant 3D-Printable Structure for (f)MRI Applications

    OpenAIRE

    Bützer, Tobias L.; Rinderknecht, Mike D.; Johannes, Gunda H.; Popp, Werner L.; Rea Lehner; Olivier Lambercy; Roger Gassert

    2016-01-01

    Grip force sensors compatible with magnetic resonance imaging (MRI) are used in human motor control and decision-making research, providing objective and sensitive behavioral outcome measures. Commercial sensors are expensive, cover limited force ranges, rely on pneumatic force transmission that cannot detect fast force changes, or are electrically active, which increases the risk of electromagnetic interference. We present the design and evaluation of a low-cost, 3D-printed, inherently MRI-c...

  8. Synthesis, activity evaluation and 3D-QSAR study of some novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine

    Institute of Scientific and Technical Information of China (English)

    Die Cheng; Deng Ke Liu; Mo Liu; Ying Liu; Wei Ren Xu; Chang Xiao Liu

    2008-01-01

    A series of novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine were synthesized and strucmrally characterized by 1H NMR and MS. Their in vivo anti-platelet aggregation activities were evaluated. A 3D-QSAR was performed using the CoMFA and the CoMSIA. This model provided useful guidelines for novel anti-platelet thienopyridines design.

  9. Evaluation of the use of laser scanning to create key models for 3D printing separate from and augmenting visible light sensing

    Science.gov (United States)

    Straub, Jeremy; Kerlin, Scott

    2016-05-01

    The illicit creation of 3D printed keys is problematic as it can allow intruders nearly undetectable access to secure facilities. Prior work has discussed how keys can be created using visible light sensing. This paper builds on this work by evaluating the utility of keys produced with laser scanning. The quality of the model produced using a structured laser scanning approach is compared to the quality of a model produced using a similarly robust visible light sensing approach.

  10. The meaning and measurement of work fatigue: Development and evaluation of the Three-Dimensional Work Fatigue Inventory (3D-WFI).

    Science.gov (United States)

    Frone, Michael R; Tidwell, Marie-Cecile O

    2015-07-01

    Although work fatigue represents an important construct in several substantive areas, prior conceptual definitions and measures have been inadequate in a number of ways. The goals of the present study were to develop a conceptual definition and outline the desirable characteristics of a work fatigue measure, briefly examine several prior measures of work fatigue-related constructs, and develop and evaluate a new measure of work fatigue. The Three-Dimensional Work Fatigue Inventory (3D-WFI) provides separate and commensurate assessments of physical, mental, and emotional work fatigue. Results from a pilot study (n = 207) and a broader evaluative study of U.S. wage and salary workers (n = 2,477) suggest that the 3D-WFI is psychometrically sound and evinces a meaningful pattern of relations with variables that comprise the nomological network of work fatigue. As with all new measures, additional research is required to evaluate fully the utility of the 3D-WFI in research on work fatigue.

  11. DRACCAR, a new 3D-thermal mechanical computer code to simulate LOCA transient on nuclear power plants. Status of the development and the validation

    International Nuclear Information System (INIS)

    IRSN is developing the DRACCAR computational software within the scope of its safety analyses on pressurised water reactors (PWR). This software is used to study loss-of-coolant accidents in the reactor core (LOCA) or in a spent fuel storage tank, for example. During such an accident, the coolant vaporises and the fuel rods dry out, which leads to an increase of their temperature, a swelling and fuel cladding failure. This swelling is responsible for major blockage in port of the core and can jeopardize the possibility of core cooling by means of back-up systems. The 3D multi-rod software is designed to model a fuel assembly so as to assess rod cooling and the blockage rate caused by deformed rods, by taking into account mechanical and thermal interactions between rods. The software can provide a consistent interpretation of the entire experimental database for a 'single-rod' configuration or a 'rod-bundle' configuration with either real or simulator fuel, transpose these results onto a reactor scale to determine what kind of research still needs to be conducted and finally, carry out safety studies. The models developed for this software cover: Heat transfers by conduction, convection and radiation. Oxidation of Zircaloy elements (cladding, guide tubes, inner shroud layer..) as well as hydriding process which can change mechanical properties. Thermomechanical behavior of fuel cladding (deformation and failure), including bowing phenomenon. Thermohydraulics on the scale of an assembly (to couple with an appropriate software), including a reflooding model. Fuel relocation and release of fission gases. A first version (DRACCAR V1) was delivered in March 2008 and is being validated on the basis of available experimental data (EDGAR, PHEBUS LOCA, PERICLES, REBEKA, HALDEN, etc.). A second version will be released in 2012 for which a coupling, in particular in the frame of the European NURISP project, is planned to an advanced sub-channel thermal-hydraulics code CATHARE

  12. SU-E-T-624: Quantitative Evaluation of 2D Versus 3D Dosimetry for Stereotactic Volumetric Modulated Arc Delivery Using COMPASS

    Energy Technology Data Exchange (ETDEWEB)

    Vikraman, S; Karrthick, K; Rajesh, T; Sambasivaselli, R; Senniandanvar, V; Kataria, T [Medanta The Medicity, Gurgaon, Haryana (India); Manigandan, D [Sri Siddhivinayak Ganapathi Cancer hospital, Miraj, Maharastra (India); Karthikeyan, N [St Johns Medical College, Bangalore, Karnataka (India); Muthukumaran, M [Apollo Super Speciality Hospital, Chennai, Tamil Nadu (India)

    2014-06-15

    Purpose: The purpose of this study was to evaluate quantitatively 2D versus 3D dosimetry for stereotactic volumetric modulated arc delivery using COMPASS with 2D array. Methods: Twenty-five patients CT images and RT structures of different sites like brain, head and neck, thorax, abdomen and spine were taken from Multiplan planning system for this study. All these patients underwent radical stereotactic treatment in Cyberknife. For each patient, linac based VMAT stereotactic plans were generated in Monaco TPS v 3.1 using Elekta Beam Modulator MLC. Dose prescription was in the range of 5-20Gy/fraction.TPS calculated VMAT plan delivery accuracy was quantitatively evaluated with COMPASS measured dose and calculated dose based on DVH metrics. In order to ascertain the potential of COMPASS 3D dosimetry for stereotactic plan delivery, 2D fluence verification was performed with MatriXX using Multicube. Results: For each site, D{sub 9} {sub 5} was achieved with 100% of prescription dose with maximum 0.05SD. Conformity index (CI) was observed closer to 1.15 in all cases. Maximum deviation of 2.62 % was observed for D{sub 9} {sub 5} when compared TPS versus COMPASS measured. Considerable deviations were observed in head and neck cases compare to other sites. The maximum mean and standard deviation for D{sub 9} {sub 5}, average target dose and average gamma were -0.78±1.72, -1.10±1.373 and 0.39±0.086 respectively. Numbers of pixels passing 2D fluence verification were observed as a mean of 99.36% ±0.455 SD with 3% dose difference and 3mm DTA. For critical organs in head and neck cases, significant dose differences were observed in 3D dosimetry while the target doses were matched well within limit in both 2D and 3D dosimetry. Conclusion: The quantitative evaluations of 2D versus 3D dosimetry for stereotactic volumetric modulated plans showed the potential of highlighting the delivery errors. This study reveals that COMPASS 3D dosimetry is an effective tool for patient

  13. SU-C-213-05: Evaluation of a Composite Copper-Plastic Material for a 3D Printed Radiation Therapy Bolus

    Energy Technology Data Exchange (ETDEWEB)

    Vitzthum, L; Ehler, E; Sterling, D; Reynolds, T; Higgins, P; Dusenbery, K [University of Minnesota, Minneapolis, MN (United States)

    2015-06-15

    Purpose: To evaluate a novel 3D printed bolus fabricated from a copper-plastic composite as a thin flexible, custom fitting device that can replicate doses achieved with conventional bolus techniques. Methods: Two models of bolus were created on a 3D printer using a composite copper-PLA/PHA. Firstly, boluses were constructed at thicknesses of 0.4, 0.6 and 0.8 mm. Relative dose measurements were performed under the bolus with an Attix Chamber as well as with radiochromic film. Results were compared to superficial Attix Chamber measurements in a water equivalent material to determine the dosimetric water equivalence of the copper-PLA/PHA plastic. Secondly, CT images of a RANDO phantom were used to create a custom fitting bolus across the anterolateral scalp. Surface dose with the bolus placed on the RANDO phantom was measured with radiochromic film at tangential angles with 6, 10, 10 flattening filter free (FFF) and 18 MV photon beams. Results: Mean surface doses for 6, 10, 10FFF and 18 MV were measured as a percent of Dmax for the flat bolus devices of each thickness. The 0.4 mm thickness bolus was determined to be near equivalent to 2.5 mm depth in water for all four energies. Surface doses ranged from 59–63% without bolus and 85–90% with the custom 0.4 mm copper-plastic bolus relative to the prescribed dose for an oblique tangential beam arrangement on the RANDO phantom. Conclusion: Sub-millimeter thickness, 3D printed composite copper-PLA/PHA bolus can provide a build-up effect equivalent to conventional bolus. At this thickness, the 3D printed bolus allows a level of flexure that may provide more patient comfort than current 3D printing materials used in bolus fabrication while still retaining the CT based custom patient shape. Funding provided by an intra-department grant of the University of Minnesota Department of Radiation Oncology.

  14. SU-C-213-05: Evaluation of a Composite Copper-Plastic Material for a 3D Printed Radiation Therapy Bolus

    International Nuclear Information System (INIS)

    Purpose: To evaluate a novel 3D printed bolus fabricated from a copper-plastic composite as a thin flexible, custom fitting device that can replicate doses achieved with conventional bolus techniques. Methods: Two models of bolus were created on a 3D printer using a composite copper-PLA/PHA. Firstly, boluses were constructed at thicknesses of 0.4, 0.6 and 0.8 mm. Relative dose measurements were performed under the bolus with an Attix Chamber as well as with radiochromic film. Results were compared to superficial Attix Chamber measurements in a water equivalent material to determine the dosimetric water equivalence of the copper-PLA/PHA plastic. Secondly, CT images of a RANDO phantom were used to create a custom fitting bolus across the anterolateral scalp. Surface dose with the bolus placed on the RANDO phantom was measured with radiochromic film at tangential angles with 6, 10, 10 flattening filter free (FFF) and 18 MV photon beams. Results: Mean surface doses for 6, 10, 10FFF and 18 MV were measured as a percent of Dmax for the flat bolus devices of each thickness. The 0.4 mm thickness bolus was determined to be near equivalent to 2.5 mm depth in water for all four energies. Surface doses ranged from 59–63% without bolus and 85–90% with the custom 0.4 mm copper-plastic bolus relative to the prescribed dose for an oblique tangential beam arrangement on the RANDO phantom. Conclusion: Sub-millimeter thickness, 3D printed composite copper-PLA/PHA bolus can provide a build-up effect equivalent to conventional bolus. At this thickness, the 3D printed bolus allows a level of flexure that may provide more patient comfort than current 3D printing materials used in bolus fabrication while still retaining the CT based custom patient shape. Funding provided by an intra-department grant of the University of Minnesota Department of Radiation Oncology

  15. Systematical Evaluation of Mechanically Strong 3D Printed Diluted magnesium Doping Wollastonite Scaffolds on Osteogenic Capacity in Rabbit Calvarial Defects

    Science.gov (United States)

    Sun, Miao; Liu, An; Shao, Huifeng; Yang, Xianyan; Ma, Chiyuan; Yan, Shigui; Liu, Yanming; He, Yong; Gou, Zhongru

    2016-01-01

    Wollastonite (CaSiO3; CSi) ceramic is a promising bioactive material for bone defect repair due to slightly fast degradation of its porous constructs in vivo. In our previous strategy some key features of CSi ceramic have been significantly improved by dilute magnesium doping for regulating mechanical properties and biodegradation. Here we demonstrate that 6 ~ 14% of Ca substituted by Mg in CSi (CSi-Mgx, x = 6, 10, 14) can enhance the mechanical strength (>40 MPa) but not compromise biological performances of the 3D printed porous scaffolds with open porosity of 60‒63%. The in vitro cell culture tests in vitro indicated that the dilute Mg doping into CSi was beneficial for ALP activity and high expression of osteogenic marker genes of MC3T3-E1 cells in the scaffolds. A good bone tissue regeneration response and elastoplastic response in mechanical strength in vivo were determined after implantation in rabbit calvarial defects for 6‒12 weeks. Particularly, the CSi-Mg10 and CSi-Mg14 scaffolds could enhance new bone regeneration with a significant increase of newly formed bone tissue (18 ~ 22%) compared to the pure CSi (~14%) at 12 weeks post-implantation. It is reasonable to consider that, therefore, such CSi-Mgx scaffolds possessing excellent strength and reasonable degradability are promising for bone reconstruction in thin-wall bone defects. PMID:27658481

  16. Novel substituted benzothiophene and thienothiophene carboxanilides and quinolones: synthesis, photochemical synthesis, DNA-binding properties, antitumor evaluation and 3D-derived QSAR analysis.

    Science.gov (United States)

    Aleksić, Maja; Bertoša, Branimir; Nhili, Raja; Uzelac, Lidija; Jarak, Ivana; Depauw, Sabine; David-Cordonnier, Marie-Hélène; Kralj, Marijeta; Tomić, Sanja; Karminski-Zamola, Grace

    2012-06-14

    A series of new N,N-dimethylaminopropyl- and 2-imidazolinyl-substituted derivatives of benzo[b]thienyl- and thieno[2,3-b]thienylcarboxanilides and benzo[b]thieno[2,3-c]- and thieno[3',2':4,5]thieno[2,3-c]quinolones were prepared. Quinolones were prepared by the reaction of photochemical dehydrohalogenation of corresponding anilides. Carboxanilides and quinolones were tested for the antiproliferative activity. 2-Imidazolinyl-substituted derivatives showed very prominent activity. By use of the experimentally obtained antitumor measurements, 3D-derived QSAR analysis was performed for the set of compounds. Highly predictive 3D-derived QSAR models were obtained, and molecular properties that have the highest impact on antitumor activity were identified. Carboxanilides 6a-c and quinolones 9a-c and 11a were evaluated for DNA binding propensities and topoisomerases I and II inhibition as part of their mechanism of action assessment. The evaluated differences in the mode of action nicely correlate with the results of the 3D-QSAR analysis. Taken together, the results indicate which modifications of the compounds from the series should further improve their anticancer properties.

  17. Evaluation of polynomial image deformation for matching of 3D- abdominal MR-images using anatomical landmarks and for atlas construction

    CERN Document Server

    Kimiaei, S; Jonsson, E; Crafoord, J; Maguire, G Q

    1999-01-01

    The aim of this study is to compare and evaluate the potential usability of linear and non-linear (polynomial) 3D-warping for constructing an atlas by matching abdominal MR-images from a number of different individuals using manually picked anatomical landmarks. The significance of this study lies in the fact that it illustrates the potential to use polynomial matching at a local or organ level. This is a necessary requirement for constructing an atlas and for fine intra-patient image matching and fusion. Finally 3D-image warping using anatomical landmark for inter-patient intra-modality image co-registration and fusion was found to be a very powerful and robust method. Additionally it can be used for intra-patient inter- modality image matching.

  18. Synthesis, 3D-QSAR analysis and biological evaluation of quinoxaline 1,4-di-N-oxide derivatives as antituberculosis agents.

    Science.gov (United States)

    Pan, Yuanhu; Li, Panpan; Xie, Shuyu; Tao, Yanfei; Chen, Dongmei; Dai, Menghong; Hao, Haihong; Huang, Lingli; Wang, Yulian; Wang, Liye; Liu, Zhenli; Yuan, Zonghui

    2016-08-15

    A series of quinoxaline 1,4-di-N-oxide derivatives variously substituted at C-2 position were synthesized and evaluated for in vitro antimycobacterial activity. Seventeen compounds exhibited potential activity (MIC ⩽6.25μg/mL) against Mycobacterium tuberculosis (H37Rv), in particular the compounds 3d and 3j having an MIC value of 0.39μg/mL. None of the compounds exhibited cytotoxicity when using an MTT assay in VERO cells. To further investigate the structure-activity relationship, CoMFA (q(2)=0.507, r(2)=0.923) and CoMSIA (q(2)=0.665, r(2)=0.977) models were performed on the basis of antimycobacterial activity data. The 3D-QSAR study of these compounds can provide useful information for further rational design of novel quinoxaline 1,4-di-N-oxides for treatment of tuberculosis.

  19. 3D Printable Graphene Composite.

    Science.gov (United States)

    Wei, Xiaojun; Li, Dong; Jiang, Wei; Gu, Zheming; Wang, Xiaojuan; Zhang, Zengxing; Sun, Zhengzong

    2015-07-08

    In human being's history, both the Iron Age and Silicon Age thrived after a matured massive processing technology was developed. Graphene is the most recent superior material which could potentially initialize another new material Age. However, while being exploited to its full extent, conventional processing methods fail to provide a link to today's personalization tide. New technology should be ushered in. Three-dimensional (3D) printing fills the missing linkage between graphene materials and the digital mainstream. Their alliance could generate additional stream to push the graphene revolution into a new phase. Here we demonstrate for the first time, a graphene composite, with a graphene loading up to 5.6 wt%, can be 3D printable into computer-designed models. The composite's linear thermal coefficient is below 75 ppm·°C(-1) from room temperature to its glass transition temperature (Tg), which is crucial to build minute thermal stress during the printing process.

  20. 3D virtuel udstilling

    DEFF Research Database (Denmark)

    Tournay, Bruno; Rüdiger, Bjarne

    2006-01-01

    3d digital model af Arkitektskolens gård med virtuel udstilling af afgangsprojekter fra afgangen sommer 2006. 10 s.......3d digital model af Arkitektskolens gård med virtuel udstilling af afgangsprojekter fra afgangen sommer 2006. 10 s....

  1. On the Analysis and Evaluation of Direct Containment Heating with the Multidimensional Multiphase Flow Code MC3D

    OpenAIRE

    Tanguy Janin; Renaud Meignen

    2010-01-01

    In the course of a postulated severe accident in an NPP, Direct Containment Heating (DCH) may occur after an eventual failure of the vessel. DCH is related to dynamical, thermal, and chemical phenomena involved by the eventual fine fragmentation and dispersal of the corium melt out of the vessel pit. It may threaten the integrity of the containment by pressurization of its atmosphere. Several simplified modellings have been proposed in the past but they require a very strong fitting which ren...

  2. Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations

    International Nuclear Information System (INIS)

    Introduction: Three-dimensional (3D) real-time fluoroscopy cone beam CT is a promising new technique for image-guided biopsy of solid tumors. We evaluated the technical feasibility, diagnostic accuracy, and complications of this technique for guidance of large-core needle biopsy in patients with suspicious renal masses. Methods: Thirteen patients with 13 suspicious renal masses underwent large-core needle biopsy under 3D real-time fluoroscopy cone beam CT guidance. Imaging acquisition and subsequent 3D reconstruction was done by a mobile flat-panel detector (FD) C-arm system to plan the needle path. Large-core needle biopsies were taken by the interventional radiologist. Technical success, accuracy, and safety were evaluated according to the Innovation, Development, Exploration, Assessment, Long-term study (IDEAL) recommendations. Results: Median tumor size was 2.6 (range, 1.0–14.0) cm. In ten (77%) patients, the histological diagnosis corresponded to the imaging findings: five were malignancies, five benign lesions. Technical feasibility was 77% (10/13); in three patients biopsy results were inconclusive. The lesion size of these three patients was <2.5 cm. One patient developed a minor complication. Median follow-up was 16.0 (range, 6.4–19.8) months. Conclusions: 3D real-time fluoroscopy cone beam CT-guided biopsy of renal masses is feasible and safe. However, these first results suggest that diagnostic accuracy may be limited in patients with renal masses <2.5 cm.

  3. Calcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model.

    Directory of Open Access Journals (Sweden)

    Stine Krog Frandsen

    Full Text Available Calcium electroporation describes the use of high voltage electric pulses to introduce supraphysiological calcium concentrations into cells. This promising method is currently in clinical trial as an anti-cancer treatment. One very important issue is the relation between tumor cell kill efficacy-and normal cell sensitivity.Using a 3D spheroid cell culture model we have tested the effect of calcium electroporation and electrochemotherapy using bleomycin on three different human cancer cell lines: a colorectal adenocarcinoma (HT29, a bladder transitional cell carcinoma (SW780, and a breast adenocarcinoma (MDA-MB231, as well as on primary normal human dermal fibroblasts (HDF-n.The results showed a clear reduction in spheroid size in all three cancer cell spheroids three days after treatment with respectively calcium electroporation (p<0.0001 or electrochemotherapy using bleomycin (p<0.0001. Strikingly, the size of normal fibroblast spheroids was neither affected after calcium electroporation nor electrochemotherapy using bleomycin, indicating that calcium electroporation, like electrochemotherapy, will have limited adverse effects on the surrounding normal tissue when treating with calcium electroporation. The intracellular ATP level, which has previously been shown to be depleted after calcium electroporation, was measured in the spheroids after treatment. The results showed a dramatic decrease in the intracellular ATP level (p<0.01 in all four spheroid types-malignant as well as normal.In conclusion, calcium electroporation seems to be more effective in inducing cell death in cancer cell spheroids than in a normal fibroblast spheroid, even though intracellular ATP level is depleted in all spheroid types after treatment. These results may indicate an important therapeutic window for this therapy; although further studies are needed in vivo and in patients to investigate the effect of calcium electroporation on surrounding normal tissue when

  4. Face Detection with a 3D Model

    OpenAIRE

    Barbu, Adrian; Lay, Nathan; Gramajo, Gary

    2014-01-01

    This paper presents a part-based face detection approach where the spatial relationship between the face parts is represented by a hidden 3D model with six parameters. The computational complexity of the search in the six dimensional pose space is addressed by proposing meaningful 3D pose candidates by image-based regression from detected face keypoint locations. The 3D pose candidates are evaluated using a parameter sensitive classifier based on difference features relative to the 3D pose. A...

  5. 3-D multiobservable probabilistic inversion for the compositional and thermal structure of the lithosphere and upper mantle. I: a priori petrological information and geophysical observables

    Science.gov (United States)

    Afonso, J. C.; Fullea, J.; Griffin, W. L.; Yang, Y.; Jones, A. G.; D. Connolly, J. A.; O'Reilly, S. Y.

    2013-05-01

    of natural mantle samples collected from different tectonic settings (xenoliths, abyssal peridotites, ophiolite samples, etc.). This strategy relaxes more typical and restrictive assumptions such as the use of local/limited xenolith data or compositional regionalizations based on age-composition relations. We demonstrate that the combination of our ρ(m) with a L(m) that exploits the differential sensitivities of specific geophysical observables provides a general and robust inference platform to address the thermochemical structure of the lithosphere and sublithospheric upper mantle. An accompanying paper deals with the integration of these two functions into a general 3-D multiobservable Bayesian inversion method and its computational implementation.

  6. Evaluation of the User Strategy on 2d and 3d City Maps Based on Novel Scanpath Comparison Method and Graph Visualization

    Science.gov (United States)

    Dolezalova, J.; Popelka, S.

    2016-06-01

    The paper is dealing with scanpath comparison of eye-tracking data recorded during case study focused on the evaluation of 2D and 3D city maps. The experiment contained screenshots from three map portals. Two types of maps were used - standard map and 3D visualization. Respondents' task was to find particular point symbol on the map as fast as possible. Scanpath comparison is one group of the eye-tracking data analyses methods used for revealing the strategy of the respondents. In cartographic studies, the most commonly used application for scanpath comparison is eyePatterns that output is hierarchical clustering and a tree graph representing the relationships between analysed sequences. During an analysis of the algorithm generating a tree graph, it was found that the outputs do not correspond to the reality. We proceeded to the creation of a new tool called ScanGraph. This tool uses visualization of cliques in simple graphs and is freely available at www.eyetracking.upol.cz/scangraph. Results of the study proved the functionality of the tool and its suitability for analyses of different strategies of map readers. Based on the results of the tool, similar scanpaths were selected, and groups of respondents with similar strategies were identified. With this knowledge, it is possible to analyse the relationship between belonging to the group with similar strategy and data gathered from the questionnaire (age, sex, cartographic knowledge, etc.) or type of stimuli (2D, 3D map).

  7. Evaluation of the User Strategy on 2d and 3d City Maps Based on Novel Scanpath Comparison Method and Graph Visualization

    Science.gov (United States)

    Dolezalova, J.; Popelka, S.

    2016-06-01

    The paper is dealing with scanpath comparison of eye-tracking data recorded during case study focused on the evaluation of 2D and 3D city maps. The experiment contained screenshots from three map portals. Two types of maps were used - standard map and 3D visualization. Respondents' task was to find particular point symbol on the map as fast as possible. Scanpath comparison is one group of the eye-tracking data analyses methods used for revealing the strategy of the respondents. In cartographic studies, the most commonly used application for scanpath comparison is eyePatterns that output is hierarchical clustering and a tree graph representing the relationships between analysed sequences. During an analysis of the algorithm generating a tree graph, it was found that the outputs do not correspond to the reality. We proceeded to the creation of a new tool called ScanGraph. This tool uses visualization of cliques in simple graphs and is freely available at www.eyetracking.upol.cz/scangraph"target="_blank">www.eyetracking.upol.cz/scangraph. Results of the study proved the functionality of the tool and its suitability for analyses of different strategies of map readers. Based on the results of the tool, similar scanpaths were selected, and groups of respondents with similar strategies were identified. With this knowledge, it is possible to analyse the relationship between belonging to the group with similar strategy and data gathered from the questionnaire (age, sex, cartographic knowledge, etc.) or type of stimuli (2D, 3D map).

  8. Evaluation of expansion algorithm of measurement range suited for 3D shape measurement using two pitches of projected grating with light source-stepping method

    Science.gov (United States)

    Sakaguchi, Toshimasa; Fujigaki, Motoharu; Murata, Yorinobu

    2015-03-01

    Accurate and wide-range shape measurement method is required in industrial field. The same technique is possible to be used for a shape measurement of a human body for the garment industry. Compact 3D shape measurement equipment is also required for embedding in the inspection system. A shape measurement by a phase shifting method can measure the shape with high spatial resolution because the coordinates can be obtained pixel by pixel. A key-device to develop compact equipment is a grating projector. Authors developed a linear LED projector and proposed a light source stepping method (LSSM) using the linear LED projector. The shape measurement euipment can be produced with low-cost and compact without any phase-shifting mechanical systems by using this method. Also it enables us to measure 3D shape in very short time by switching the light sources quickly. A phase unwrapping method is necessary to widen the measurement range with constant accuracy for phase shifting method. A general phase unwrapping method with difference grating pitches is often used. It is one of a simple phase unwrapping method. It is, however, difficult to apply the conventional phase unwrapping algorithm to the LSSM. Authors, therefore, developed an expansion unwrapping algorithm for the LSSM. In this paper, an expansion algorithm of measurement range suited for 3D shape measurement using two pitches of projected grating with the LSSM was evaluated.

  9. Three-Dimensional Numerical Evaluation of Thermal Performance of Uninsulated Wall Assemblies

    Energy Technology Data Exchange (ETDEWEB)

    Ridouane, El Hassan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bianchi, Marcus V.A. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2011-11-01

    This study describes a detailed 3D computational fluid dynamics model that evaluates the thermal performance of uninsulated wall assemblies. It accounts for conduction through framing, convection, and radiation and allows for material property variations with temperature. This research was presented at the ASME 2011 International Mechanical Engineering Congress and Exhibition; Denver, Colorado; November 11-17, 2011

  10. Blender 3D cookbook

    CERN Document Server

    Valenza, Enrico

    2015-01-01

    This book is aimed at the professionals that already have good 3D CGI experience with commercial packages and have now decided to try the open source Blender and want to experiment with something more complex than the average tutorials on the web. However, it's also aimed at the intermediate Blender users who simply want to go some steps further.It's taken for granted that you already know how to move inside the Blender interface, that you already have 3D modeling knowledge, and also that of basic 3D modeling and rendering concepts, for example, edge-loops, n-gons, or samples. In any case, it'

  11. Application of 3D Scanned Imaging Methodology for Volume, Surface Area, and Envelope Density Evaluation of Densified Biomass

    Science.gov (United States)

    Measurement of surface area, volume, and density is an essential for quantifying, evaluating, and designing the biomass densification, storage, and transport operations. Acquiring accurate and repeated measurements of these parameters for hygroscopic densified biomass are not straightforward and on...

  12. On Evaluating circulation and temperature stratification under changing water levels in Lake Mead with a 3D hydrodynamic model

    Science.gov (United States)

    Li, Y.; Acharya, K.; Chen, D.; Stone, M.; Yu, Z.; Young, M.; Zhu, J.; Shafer, D. S.; Warwick, J. J.

    2009-12-01

    Sustained drought in the western United States since 2000 has led to a significant drop (about 35 meters) in the water level of Lake Mead, the largest reservoir by volume in United States. The drought combined with rapid urban development in southern Nevada and emergence of invasive species has threatened the water quality and ecological processes in Lake Mead. A three-dimensional hydrodynamic model, Environmental Fluid Dynamics Code (EFDC), was applied to investigate lake circulation and temperature stratification in parts of Lake Mead (Las Vegas Bay and Boulder Basin) under changing water levels. Besides the inflow from Las Vegas Wash and the Colorado River, the model considered atmospheric changes as well as the boundary conditions restricted by the operation of Hoover Dam. The model was calibrated and verified by using observed data including water level, velocity, and temperature from 2003 and 2005. The model was applied to study the hydrodynamic processes at water level 366.8 m (year 2000) and at water level 338.2 m (year 2008). The high-stage simulation described the pre-drought lake hydrodynamic processes while the low-stage simulation highlighted the drawdown impact on such processes. The results showed that both inflow and wind-driven mixing process played major roles in the thermal stratification and lake circulation in both cases. However, the atmospheric boundary played a more important role than inflow temperature on thermal stratification of Lake Mead during water level decline. Further, the thermal stratification regime and flow circulation pattern in shallow lake regions (e.g.., the Boulder Basin area) were most impacted. The temperature of the lake at the high-stage was more sensitive to inflow temperatures than at low-stage. Furthermore, flow velocities decreased with the decreasing water level due to reduction in wind impacts, particularly in shallow areas of the lake. Such changes in temperature and lake current due to present drought have a

  13. Use of combined Hartree–Fock–Roothaan theory in evaluation of lowest states of $K[Ar]4s^0 3d^1$ and $Cr^+ [Ar]4s^0 3d^5$ isoelectronic series over noninteger -Slater type orbitals

    Indian Academy of Sciences (India)

    I I Guseinov; M Erturk; E Sahin

    2011-01-01

    By using noninteger n-Slater type orbitals in combined Hartree–Fock–Roothaan method, self-consistent field calculations of orbital and lowest states energies have been performed for the isoelectronic series of open shell systems $K[Ar]4s^0 3d^1 ({}^2D) (Z = 19–30)$ and $Cr^+[Ar]4s^0 3d^5 ({}^6 S) (Z = 24–30)$. The results of the calculations for the orbital and total energies obtained by using minimal basis-sets of noninteger -Slater type orbitals are given in the tables. The results are compared with the extended-basis Hartree–Fock computations. The orbital and total energies are in good agreement with those presented in the literature. The results can be useful in the study of various properties of heavy atomic systems when the combined Hartree–Fock–Roothaan approach is employed.

  14. A systematic method for using 3D echocardiography to evaluate tricuspid valve insufficiency in hypoplastic left heart syndrome

    Directory of Open Access Journals (Sweden)

    Christopher Robin Mart

    2014-01-01

    We have proposed a systematic method for evaluating and displaying the TV using 3DE which can provide significant insight into the mechanisms causing TVI in HLHS. This has the potential to improve both the surgical approach to repairing the valve and, ultimately, patient outcomes.

  15. Comparative evaluation of the accuracy of linear measurements between cone beam computed tomography and 3D microtomography

    OpenAIRE

    Francesca Mangione; Deborah Meleo; Marco Talocco; Raffaella Pecci; Luciano Pacifici; Rossella Bedini

    2013-01-01

    OBJECTIVE: The aim of this study was to evaluate the influence of artifacts on the accuracy of linear measurements estimated with a common cone beam computed tomography (CBCT) system used in dental clinical practice, by comparing it with microCT system as standard reference. MATERIALS AND METHODS: Ten bovine bone cylindrical samples containing one implant each, able to provide both points of reference and image quality degradation, have been scanned by CBCT and microCT systems. Thanks to the ...

  16. Retrospective evaluation of dosimetric quality for prostate carcinomas treated with 3D conformal, intensity modulated and volumetric modulated arc radiotherapy

    International Nuclear Information System (INIS)

    This study examines and compares the dosimetric quality of radiotherapy treatment plans for prostate carcinoma across a cohort of 163 patients treated across five centres: 83 treated with three-dimensional conformal radiotherapy (3DCRT), 33 treated with intensity modulated radiotherapy (IMRT) and 47 treated with volumetric modulated arc therapy (VMAT). Treatment plan quality was evaluated in terms of target dose homogeneity and organs at risk (OAR), through the use of a set of dose metrics. These included the mean, maximum and minimum doses; the homogeneity and conformity indices for the target volumes; and a selection of dose coverage values that were relevant to each OAR. Statistical significance was evaluated using two-tailed Welch's T-tests. The Monte Carlo DICOM ToolKit software was adapted to permit the evaluation of dose metrics from DICOM data exported from a commercial radiotherapy treatment planning system. The 3DCRT treatment plans offered greater planning target volume dose homogeneity than the other two treatment modalities. The IMRT and VMAT plans offered greater dose reduction in the OAR: with increased compliance with recommended OAR dose constraints, compared to conventional 3DCRT treatments. When compared to each other, IMRT and VMAT did not provide significantly different treatment plan quality for like-sized tumour volumes. This study indicates that IMRT and VMAT have provided similar dosimetric quality, which is superior to the dosimetric quality achieved with 3DCRT

  17. Adaptation, Commissioning, and Evaluation of a 3D Treatment Planning System for High-Resolution Small-Animal Irradiation.

    Science.gov (United States)

    Jeong, Jeho; Chen, Qing; Febo, Robert; Yang, Jie; Pham, Hai; Xiong, Jian-Ping; Zanzonico, Pat B; Deasy, Joseph O; Humm, John L; Mageras, Gig S

    2016-06-01

    Although spatially precise systems are now available for small-animal irradiations, there are currently limited software tools available for treatment planning for such irradiations. We report on the adaptation, commissioning, and evaluation of a 3-dimensional treatment planning system for use with a small-animal irradiation system. The 225-kV X-ray beam of the X-RAD 225Cx microirradiator (Precision X-Ray) was commissioned using both ion-chamber and radiochromic film for 10 different collimators ranging in field size from 1 mm in diameter to 40 × 40 mm(2) A clinical 3-dimensional treatment planning system (Metropolis) developed at our institution was adapted to small-animal irradiation by making it compatible with the dimensions of mice and rats, modeling the microirradiator beam orientations and collimators, and incorporating the measured beam data for dose calculation. Dose calculations in Metropolis were verified by comparison with measurements in phantoms. Treatment plans for irradiation of a tumor-bearing mouse were generated with both the Metropolis and the vendor-supplied software. The calculated beam-on times and the plan evaluation tools were compared. The dose rate at the central axis ranges from 74 to 365 cGy/min depending on the collimator size. Doses calculated with Metropolis agreed with phantom measurements within 3% for all collimators. The beam-on times calculated by Metropolis and the vendor-supplied software agreed within 1% at the isocenter. The modified 3-dimensional treatment planning system provides better visualization of the relationship between the X-ray beams and the small-animal anatomy as well as more complete dosimetric information on target tissues and organs at risk. It thereby enhances the potential of image-guided microirradiator systems for evaluation of dose-response relationships and for preclinical experimentation generally. PMID:25948321

  18. Description of an evaluation system for knee kinematics in ligament lesions, by means of optical tracking and 3D tomography,

    Directory of Open Access Journals (Sweden)

    Tiago Lazzaretti Fernandes

    2014-10-01

    Full Text Available Objective:To describe and demonstrate the viability of a method for evaluating knee kine matics, by means of a continuous passive motion (CPM machine, before and after anterio cruciate ligament (ACL injury.Methods:This study was conducted on a knee from a cadaver, in a mechanical pivot-shif simulator, with evaluations using optical tracking, and also using computed tomography.Results:This study demonstrated the viability of a protocol for measuring the rotation an translation of the knee, using reproducible and objective tools (error<0.2mm. The mech anized provocation system of the pivot-shift test was independent of the examiner an always allowed the same angular velocity and traction of 20 N throughout the movement.Conclusion:The clinical relevance of this method lies in making inferences about the in viv behavior of a knee with an ACL injury and providing greater methodological quality in futur studies for measuring surgical techniques with grafts in relatively close positions.

  19. Unwrapped wavefront evaluation in phase-shifting interferometry based on 3D dynamic fringe processing in state space.

    Science.gov (United States)

    Garifullin, Azat; Gurov, Igor; Volynsky, Maxim

    2016-08-01

    Recovery of an unwrapped wavefront in phase-shifting interferometry is considered when the wavefront phase increments are determined between previous and subsequent fringe patterns as well as between adjacent pixels of the current fringe pattern. A parametric model of a three-dimensional interferometric signal and the recurrence processing algorithm in state space are utilized, providing an evaluation of an unwrapped wavefront phase at each phase shift step in dynamic mode. Estimates of the achievable accuracy and experimental results of the wavefront recovery are presented. Comparison with the conventional seven-frame phase-shifting algorithm, which is one of the most accurate, confirmed the high accuracy and noise immunity of the proposed method. PMID:27505660

  20. Thermally activated 3D to 2D structural transformation of [Ni{sub 2}(en){sub 2}(H{sub 2}O){sub 6}(pyr)]·4H{sub 2}O flexible coordination polymer

    Energy Technology Data Exchange (ETDEWEB)

    Begović, Nebojša N. [Faculty of Physical Chemistry, University of Belgrade (Serbia); Institute of General and Physical Chemistry, Belgrade (Serbia); Blagojević, Vladimir A. [Faculty of Physical Chemistry, University of Belgrade (Serbia); Ostojić, Sanja B.; Radulović, Aleksandra M. [Institute of General and Physical Chemistry, Belgrade (Serbia); Poleti, Dejan [Faculty of Technology and Metallurgy, University of Belgrade (Serbia); Minić, Dragica M., E-mail: dminic@ffh.bg.ac.rs [Faculty of Physical Chemistry, University of Belgrade (Serbia); Department of Biomedical Sciences, State University of Novi Pazar (Serbia)

    2015-01-15

    Thermally activated 3D to 2D structural transformation of the binuclear [Ni{sub 2}(en){sub 2}(H{sub 2}O){sub 6}(pyr)]·4H{sub 2}O complex was investigated using a combination of theoretical and experimental methods. Step-wise thermal degradation (dehydration followed by release of ethylene diamine) results in two layered flexible coordination polymer structures. Dehydration process around 365 K results in a conjugated 2D structure with weak interlayer connectivity. It was shown to be a reversible 3D to 2D framework transformation by a guest molecule, and rehydration of the dehydration product occurs at room temperature in saturated water vapor. Rehydrated complex exhibits lower dehydration temperature, due to decreased average crystalline size, with higher surface area resulting in easier release and diffusion of water during dehydration. Thermal degradation of dehydration around 570 K, results in loss of ethylene diamine, producing a related 2D layered polymer structure, without interconnectivity between individual polymer layers. - Highlights: • Reversible 3D to 2D framework topochemical transformation on dehydration around 365 K. • Resulting polymer exhibits 2D layered structure with weak interlayer connectivity. • Dehydration is fully reversible in saturated water vapor at room temperature. • Further degradation around 570 K yields 2D polymer without interlayer connectivity. • 2D polymer exhibits conjugated electronic system.

  1. 3D Projection Installations

    DEFF Research Database (Denmark)

    Halskov, Kim; Johansen, Stine Liv; Bach Mikkelsen, Michelle

    2014-01-01

    Three-dimensional projection installations are particular kinds of augmented spaces in which a digital 3-D model is projected onto a physical three-dimensional object, thereby fusing the digital content and the physical object. Based on interaction design research and media studies, this article...... contributes to the understanding of the distinctive characteristics of such a new medium, and identifies three strategies for designing 3-D projection installations: establishing space; interplay between the digital and the physical; and transformation of materiality. The principal empirical case, From...... Fingerplan to Loop City, is a 3-D projection installation presenting the history and future of city planning for the Copenhagen area in Denmark. The installation was presented as part of the 12th Architecture Biennale in Venice in 2010....

  2. Evaluation of a prototype 3D ultrasound system for multimodality imaging of cervical nodes for adaptive radiation therapy

    Science.gov (United States)

    Fraser, Danielle; Fava, Palma; Cury, Fabio; Vuong, Te; Falco, Tony; Verhaegen, Frank

    2007-03-01

    Sonography has good topographic accuracy for superficial lymph node assessment in patients with head and neck cancers. It is therefore an ideal non-invasive tool for precise inter-fraction volumetric analysis of enlarged cervical nodes. In addition, when registered with computed tomography (CT) images, ultrasound information may improve target volume delineation and facilitate image-guided adaptive radiation therapy. A feasibility study was developed to evaluate the use of a prototype ultrasound system capable of three dimensional visualization and multi-modality image fusion for cervical node geometry. A ceiling-mounted optical tracking camera recorded the position and orientation of a transducer in order to synchronize the transducer's position with respect to the room's coordinate system. Tracking systems were installed in both the CT-simulator and radiation therapy treatment rooms. Serial images were collected at the time of treatment planning and at subsequent treatment fractions. Volume reconstruction was performed by generating surfaces around contours. The quality of the spatial reconstruction and semi-automatic segmentation was highly dependent on the system's ability to track the transducer throughout each scan procedure. The ultrasound information provided enhanced soft tissue contrast and facilitated node delineation. Manual segmentation was the preferred method to contour structures due to their sonographic topography.

  3. Evaluation of planar 3D electrical capacitance tomography: from single-plane to dual-plane configuration

    International Nuclear Information System (INIS)

    Electrical capacitance tomography (ECT) is a non-invasive imaging technique that is sensitive to the dielectric permittivity property of an object. Conventional ECT systems have a circular/cylindrical or rectangular geometry, in which the electrode plates are usually spaced equally around the tank. It is the most common configuration as it can be easily applied to industrial pipelines. However, under some circumstances, the full access to the imaging geometry may not be applicable due to the limitation of the process area. In those cases, and with limited access, planar ECT sensors can fit the process structure if access to only one side is possible. A single-plane ECT configuration has been proposed for such applications. However, the planar array often suffers from a lack of sensitivity and difficulty with depth detection. To better understand these limitations we investigate the imaging performance from the single-plane ECT to dual-plane ECT structure. The limitations and constraints of the planar configuration will also be discussed. Several experiments were conducted using both single-plane and dual-plane configurations to evaluate the potential applications. The initial results are promising, and the quality of the reconstructed images are compared with the real condition for process validation. (paper)

  4. Comparative evaluation of the accuracy of linear measurements between cone beam computed tomography and 3D microtomography

    Directory of Open Access Journals (Sweden)

    Francesca Mangione

    2013-09-01

    Full Text Available OBJECTIVE: The aim of this study was to evaluate the influence of artifacts on the accuracy of linear measurements estimated with a common cone beam computed tomography (CBCT system used in dental clinical practice, by comparing it with microCT system as standard reference. MATERIALS AND METHODS: Ten bovine bone cylindrical samples containing one implant each, able to provide both points of reference and image quality degradation, have been scanned by CBCT and microCT systems. Thanks to the software of the two systems, for each cylindrical sample, two diameters taken at different levels, by using implants different points as references, have been measured. Results have been analyzed by ANOVA and a significant statistically difference has been found. RESULTS AND DISCUSSION: Due to the obtained results, in this work it is possible to say that the measurements made with the two different instruments are still not statistically comparable, although in some samples were obtained similar performances and therefore not statistically significant. CONCLUSION: With the improvement of the hardware and software of CBCT systems, in the near future the two instruments will be able to provide similar performances.

  5. Simulation of at-sensor radiance over land for proposed thermal channels of Imager payload onboard INSAT-3D satellite using MODTRAN model

    Indian Academy of Sciences (India)

    M R Pandya; D B Shah; H J Trivedi; S Panigrahy

    2011-02-01

    INSAT-3D is the new generation Indian satellite designed for improved Earth observations through two payloads – Imager and Sounder. Study was conducted with an aim of simulating satellite level signal over land in the infrared channels of the Imager payload using a radiative transfer model MODTRAN. Satellite level at-sensor radiance corresponding to all four infrared channels of INSAT-3D Imager payload is obtained using MODTRAN and sensitivity of at-sensor radiance was inferred as a function of input parameters namely, surface temperature, emissivity, view angle and atmospheric water vapour, which is helpful in understanding the signal simulation scheme needed for retrieving a very critical parameter namely, land surface temperature.

  6. Herramientas SIG 3D

    Directory of Open Access Journals (Sweden)

    Francisco R. Feito Higueruela

    2010-04-01

    Full Text Available Applications of Geographical Information Systems on several Archeology fields have been increasing during the last years. Recent avances in these technologies make possible to work with more realistic 3D models. In this paper we introduce a new paradigm for this system, the GIS Thetrahedron, in which we define the fundamental elements of GIS, in order to provide a better understanding of their capabilities. At the same time the basic 3D characteristics of some comercial and open source software are described, as well as the application to some samples on archeological researchs

  7. TOWARDS: 3D INTERNET

    OpenAIRE

    Ms. Swapnali R. Ghadge

    2013-01-01

    In today’s ever-shifting media landscape, it can be a complex task to find effective ways to reach your desired audience. As traditional media such as television continue to lose audience share, one venue in particular stands out for its ability to attract highly motivated audiences and for its tremendous growth potential the 3D Internet. The concept of '3D Internet' has recently come into the spotlight in the R&D arena, catching the attention of many people, and leading to a lot o...

  8. Bootstrapping 3D fermions

    Science.gov (United States)

    Iliesiu, Luca; Kos, Filip; Poland, David; Pufu, Silviu S.; Simmons-Duffin, David; Yacoby, Ran

    2016-03-01

    We study the conformal bootstrap for a 4-point function of fermions in 3D. We first introduce an embedding formalism for 3D spinors and compute the conformal blocks appearing in fermion 4-point functions. Using these results, we find general bounds on the dimensions of operators appearing in the ψ × ψ OPE, and also on the central charge C T . We observe features in our bounds that coincide with scaling dimensions in the GrossNeveu models at large N . We also speculate that other features could coincide with a fermionic CFT containing no relevant scalar operators.

  9. Interaktiv 3D design

    DEFF Research Database (Denmark)

    Villaume, René Domine; Ørstrup, Finn Rude

    2002-01-01

    Projektet undersøger potentialet for interaktiv 3D design via Internettet. Arkitekt Jørn Utzons projekt til Espansiva blev udviklet som et byggesystem med det mål, at kunne skabe mangfoldige planmuligheder og mangfoldige facade- og rumudformninger. Systemets bygningskomponenter er digitaliseret som...... 3D elementer og gjort tilgængelige. Via Internettet er det nu muligt at sammenstille og afprøve en uendelig  række bygningstyper som  systemet blev tænkt og udviklet til....

  10. Evaluating a 3-D transport model of atmospheric CO2 using ground-based, aircraft, and space-borne data

    Directory of Open Access Journals (Sweden)

    J.-D. Paris

    2010-07-01

    Full Text Available We evaluate the GEOS-Chem atmospheric transport model (v8-02-01 of CO2 over 2003–2006, driven by GEOS-4 and GEOS-5 meteorology from the NASA Goddard Global Modelling and Assimilation Office, using surface, aircraft and space-borne concentration measurements of CO2. We use an established ensemble Kalman filter to estimate a posteriori biospheric+biomass burning (BS+BB and oceanic (OC CO2 fluxes from 22 geographical regions, following the TransCom 3 protocol, using boundary layer CO2 data from a subset of GLOBALVIEW surface sites. Global annual net BS+BB+OC CO2 fluxes over 2004–2006 for GEOS-4 (GEOS-5 meteorology are −4.4±0.9 (−4.2±0.9, −3.9±0.9 (−4.5±0.9, and −5.2±0.9 (−4.9±0.9 Pg C yr−1 , respectively. The regional a posteriori fluxes are broadly consistent in the sign and magnitude of the TransCom-3 study for 1992–1996, but we find larger net sinks over northern and southern continents. We find large departures from our a priori over Europe during summer 2003, over temperate Eurasia during 2004, and over North America during 2005, reflecting an incomplete description of terrestrial carbon dynamics. We find GEOS-4 (GEOS-5 a posteriori CO2 concentrations reproduce the observed surface trend of 1.91–2.43 ppm yr−1, depending on latitude, within 0.15 ppm yr−1 (0.2 ppm yr−1 and the seasonal cycle within 0.2 ppm (0.2 ppm at all latitudes. We find the a posteriori model reproduces the aircraft vertical profile measurements of CO2 over North America and Siberia generally within 1.5 ppm in the free and upper troposphere but can be biased by up to 4–5 ppm in the boundary layer at the start and end of the growing season. The model has a small negative bias in the free troposphere CO2 trend (1.95–2.19 ppm yr−1 compared to AIRS data which has a trend of 2.21–2.63 ppm yr−1 during 2004–2006, consistent with surface data. Model CO2 concentrations in the upper troposphere, evaluated using CONTRAIL (Comprehensive

  11. Evaluating a 3-D transport model of atmospheric CO2 using ground-based, aircraft, and space-borne data

    Directory of Open Access Journals (Sweden)

    J.-D. Paris

    2011-03-01

    Full Text Available We evaluate the GEOS-Chem atmospheric transport model (v8-02-01 of CO2 over 2003–2006, driven by GEOS-4 and GEOS-5 meteorology from the NASA Goddard Global Modeling and Assimilation Office, using surface, aircraft and space-borne concentration measurements of CO2. We use an established ensemble Kalman Filter to estimate a posteriori biospheric+biomass burning (BS + BB and oceanic (OC CO2 fluxes from 22 geographical regions, following the TransCom-3 protocol, using boundary layer CO2 data from a subset of GLOBALVIEW surface sites. Global annual net BS + BB + OC CO2 fluxes over 2004–2006 for GEOS-4 (GEOS-5 meteorology are −4.4 ± 0.9 (−4.2 ± 0.9, −3.9 ± 0.9 (−4.5 ± 0.9, and −5.2 ± 0.9 (−4.9 ± 0.9 PgC yr−1, respectively. After taking into account anthropogenic fossil fuel and bio-fuel emissions, the global annual net CO2 emissions for 2004–2006 are estimated to be 4.0 ± 0.9 (4.2 ± 0.9, 4.8 ± 0.9 (4.2 ± 0.9, and 3.8 ± 0.9 (4.1 ± 0.9 PgC yr−1, respectively. The estimated 3-yr total net emission for GEOS-4 (GEOS-5 meteorology is equal to 12.5 (12.4 PgC, agreeing with other recent top-down estimates (12–13 PgC. The regional a posteriori fluxes are broadly consistent in the sign and magnitude of the TransCom-3 study for 1992–1996, but we find larger net sinks over northern and southern continents. We find large departures from our a priori over Europe during summer 2003, over temperate Eurasia during 2004, and over North America during 2005, reflecting an incomplete description of terrestrial carbon dynamics. We find GEOS-4 (GEOS-5 a posteriori CO2 concentrations reproduce the observed surface trend of 1.91–2.43 ppm yr−1 (parts per million per year, depending on latitude, within 0.15 ppm yr−1 (0.2 ppm yr−1 and the seasonal cycle within 0.2 ppm (0.2 ppm at all latitudes. We find the a posteriori model reproduces the aircraft vertical profile measurements of CO2 over North America and Siberia generally within 1

  12. DYNA3D2000*, Explicit 3-D Hydrodynamic FEM Program

    International Nuclear Information System (INIS)

    1 - Description of program or function: DYNA3D2000 is a nonlinear explicit finite element code for analyzing 3-D structures and solid continuum. The code is vectorized and available on several computer platforms. The element library includes continuum, shell, beam, truss and spring/damper elements to allow maximum flexibility in modeling physical problems. Many materials are available to represent a wide range of material behavior, including elasticity, plasticity, composites, thermal effects and rate dependence. In addition, DYNA3D has a sophisticated contact interface capability, including frictional sliding, single surface contact and automatic contact generation. 2 - Method of solution: Discretization of a continuous model transforms partial differential equations into algebraic equations. A numerical solution is then obtained by solving these algebraic equations through a direct time marching scheme. 3 - Restrictions on the complexity of the problem: Recent software improvements have eliminated most of the user identified limitations with dynamic memory allocation and a very large format description that has pushed potential problem sizes beyond the reach of most users. The dominant restrictions remain in code execution speed and robustness, which the developers constantly strive to improve

  13. VIRTUAL ANTI-BULLYING VILLAGE PROJECT FOR COPING WITH BULLYING AND CYBERBULLYING WITHIN A 3D VIRTUAL LEARNING ENVIRONMENT: EVALUATION RESEARCH

    Directory of Open Access Journals (Sweden)

    Dorit Olenik Shemesh

    2014-12-01

    Full Text Available The current study aims to evaluate the implementation of a unique educational project- The Virtual Anti-Bullying Village for Kids and Teens (ABV4KIDS that was designed and operated by the European Commission. A 3D virtual environment as an innovative, international project for adolescents, focused on knowledge acquisition and new ways of coping with bullying and cyberbullying. Sixty seventh graders-Israeli adolescents-completed five questionnaires before and after the project to assess its impacts regarding cyberbullying and socio-emotional variables. They evaluated the project as important, enjoyable, and increasing their knowledge about cyberbullying, but expressed a need for more practical tools for coping. At the end of the project, the control group reported more cyberbullying experiences, as well as a decrease in social support, whereas the research group reported no changes in cyberbullying experiences and in socio-emotional aspects.

  14. Performance evaluation of CCD- and mobile-phone-based near-infrared fluorescence imaging systems with molded and 3D-printed phantoms

    Science.gov (United States)

    Wang, Bohan; Ghassemi, Pejhman; Wang, Jianting; Wang, Quanzeng; Chen, Yu; Pfefer, Joshua

    2016-03-01

    Increasing numbers of devices are emerging which involve biophotonic imaging on a mobile platform. Therefore, effective test methods are needed to ensure that these devices provide a high level of image quality. We have developed novel phantoms for performance assessment of near infrared fluorescence (NIRF) imaging devices. Resin molding and 3D printing techniques were applied for phantom fabrication. Comparisons between two imaging approaches - a CCD-based scientific camera and an NIR-enabled mobile phone - were made based on evaluation of the contrast transfer function and penetration depth. Optical properties of the phantoms were evaluated, including absorption and scattering spectra and fluorescence excitation-emission matrices. The potential viability of contrastenhanced biological NIRF imaging with a mobile phone is demonstrated, and color-channel-specific variations in image quality are documented. Our results provide evidence of the utility of novel phantom-based test methods for quantifying image quality in emerging NIRF devices.

  15. The evaluation of thermal hotels' online reviews

    OpenAIRE

    BERTAN, Serkan; Bayram, Murat; Benzergil, Nisan

    2015-01-01

    The main objective of this study was to evaluate the perceptions related to the online user reviews of thermal hotels. Specifically, it was investigated whether perceptions towards value (V), location (L), sleep quality (SQ), rooms (R), cleanliness (C), service (S) and factors influencing general evaluation depend on the star numbers of hotels, the location of the hotels and the nationalities of participants. In order to obtain data on perceptions of consumers towards thermal hotels in Turkey...

  16. Tangible 3D Modelling

    DEFF Research Database (Denmark)

    Hejlesen, Aske K.; Ovesen, Nis

    2012-01-01

    This paper presents an experimental approach to teaching 3D modelling techniques in an Industrial Design programme. The approach includes the use of tangible free form models as tools for improving the overall learning. The paper is based on lecturer and student experiences obtained through facil...

  17. 3D Harmonic Echocardiography:

    NARCIS (Netherlands)

    M.M. Voormolen

    2007-01-01

    textabstractThree dimensional (3D) echocardiography has recently developed from an experimental technique in the ’90 towards an imaging modality for the daily clinical practice. This dissertation describes the considerations, implementation, validation and clinical application of a unique

  18. High-resolution cartilage imaging of the knee at 3 T: Basic evaluation of modern isotropic 3D MR-sequences

    International Nuclear Information System (INIS)

    Purpose: To evaluate qualitative and quantitative image quality parameters of isotropic three-dimensional (3D) cartilage-imaging magnetic resonance (MR)-sequences at 3 T. Materials and methods: The knees of 10 healthy volunteers (mean age, 24.4 ± 5.6 years) were scanned at a 3 T MR scanner with water-excited 3D Fast-Low Angle Shot (FLASH), True Fast Imaging with Steady-state Precession (TrueFISP), Sampling Perfection with Application-optimized Contrast using different flip-angle Evolutions (SPACE) as well as conventional and two individually weighted Double-Echo Steady-State (DESS) sequences. The MR images were evaluated qualitatively and quantitatively (signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), SNR efficiency, CNR efficiency). Quantitative parameters were compared by means of a Tukey-test and sequences were ranked according to SNR/CNR, SNR/CNR efficiency and qualitative image grading. Results: The highest SNR was measured for SPACE (34.0 ± 5.6), the highest CNR/CNR efficiency (cartilage/fluid) for the individually weighted DESS (46.9 ± 18.0/2.18 ± 0.84). SPACE, individually weighted and conventional DESS were ranked best with respect to SNR/CNR and SNR/CNR efficiency. The DESS sequences also performed best in the qualitative evaluation. TrueFISP performed worse, FLASH worst. The individually weighted DESS sequences were generally better than the conventional DESS with the significant increase of cartilage-fluid contrast (46.9 ± 18.0/31.9 ± 11.4 versus 22.0 ± 7.3) as main advantage. Conclusion: Individually weighted DESS is the most promising candidate; all tested sequences performed better than FLASH.

  19. Feasibility of Using Volumetric Contrast-Enhanced Ultrasound with a 3-D Transducer to Evaluate Therapeutic Response after Targeted Therapy in Rabbit Hepatic VX2 Carcinoma.

    Science.gov (United States)

    Kim, Jeehyun; Kim, Jung Hoon; Yoon, Soon Ho; Choi, Won Seok; Kim, Young Jae; Han, Joon Koo; Choi, Byung-Ihn

    2015-12-01

    The aim of this study was to assess the feasibility of using dynamic contrast-enhanced ultrasound (DCE-US) with a 3-D transducer to evaluate therapeutic responses to targeted therapy. Rabbits with hepatic VX2 carcinomas, divided into a treatment group (n = 22, 30 mg/kg/d sorafenib) and a control group (n = 13), were evaluated with DCE-US using 2-D and 3-D transducers and computed tomography (CT) perfusion imaging at baseline and 1 d after the first treatment. Perfusion parameters were collected, and correlations between parameters were analyzed. In the treatment group, both volumetric and 2-D DCE-US perfusion parameters, including peak intensity (33.2 ± 19.9 vs. 16.6 ± 10.7, 63.7 ± 20.0 vs. 30.1 ± 19.8), slope (15.3 ± 12.4 vs. 5.7 ± 4.5, 37.3 ± 20.4 vs. 15.7 ± 13.0) and area under the curve (AUC; 1004.1 ± 560.3 vs. 611.4 ± 421.1, 1332.2 ± 708.3 vs. 670.4 ± 388.3), had significantly decreased 1 d after the first treatment (p = 0.00). In the control group, 2-D DCE-US revealed that peak intensity, time to peak and slope had significantly changed (p AUC, AUC during wash-in and AUC during wash-out had significantly changed (p = 0.00). CT perfusion imaging parameters, including blood flow, blood volume and permeability of the capillary vessel surface, had significantly decreased in the treatment group (p = 0.00); however, in the control group, peak intensity and blood volume had significantly increased (p = 0.00). It is feasible to use DCE-US with a 3-D transducer to predict early therapeutic response after targeted therapy because perfusion parameters, including peak intensity, slope and AUC, significantly decreased, which is similar to the trend observed for 2-D DCE-US and CT perfusion imaging parameters. PMID:26365926

  20. Histopathological evaluation of tissue undergoing thermal insult

    Science.gov (United States)

    Chaudhary, Minal; Bonde, Dushyant; Patil, Swati; Gawande, Madhuri; Hande, Alka; Jain, Deepali

    2016-01-01

    Context: Thermal insult is the major cause of thermal injury or death and in case of death due to thermal injury the body often has to be recovered from the site. Histologically, one can predict whether the victim was alive or dead when the fire was on going. However, determination of probable cause of thermal insult to which victim subjected to be difficult when the victim's body is found somewhere else from the crime scene or accident site or found alone. Hence, histopathological evaluation of the tissue which has undergone thermal insult in such conditions could help to place evidence in front of law officials, regarding probable condition, or scenario at time of burn of victim. Aims: Keeping this as a criteria in this study we aim to evaluate burnt tissue histopathologically, that undergone various degree of thermal insult, which simulates various real life scenario for mortality in burn cases. Settings and Design: We evaluate the changes in hematoxylin and eosin staining pattern of tissue which has undergone thermal insult compared to normal tissue and also the progressive changes in staining pattern, architectural, and cellular details. Materials and Methods: Samples were taken from the patients, in various surgical procedures. Each sample was cut into five parts with close margins so that each burnt tissue is evaluated for same field or region. The tissue that obtained was immediately subjected to varying degree of temperature over a specific period so as to simulate the various real-life condition. Then the tissues were fixed, processed, and stained with routine H and E staining. The processed slides of tissue were examined under the microscope, and the staining, and architectural changes were evaluated and described. Results: Results show that there was a progressive changes in the architectural pattern of the epithelium and connective tissue showing cleft formation and vacuolization, staining pattern also shows mixing of stains progressively as the

  1. 3D Printable Graphene Composite

    Science.gov (United States)

    Wei, Xiaojun; Li, Dong; Jiang, Wei; Gu, Zheming; Wang, Xiaojuan; Zhang, Zengxing; Sun, Zhengzong

    2015-07-01

    In human being’s history, both the Iron Age and Silicon Age thrived after a matured massive processing technology was developed. Graphene is the most recent superior material which could potentially initialize another new material Age. However, while being exploited to its full extent, conventional processing methods fail to provide a link to today’s personalization tide. New technology should be ushered in. Three-dimensional (3D) printing fills the missing linkage between graphene materials and the digital mainstream. Their alliance could generate additional stream to push the graphene revolution into a new phase. Here we demonstrate for the first time, a graphene composite, with a graphene loading up to 5.6 wt%, can be 3D printable into computer-designed models. The composite’s linear thermal coefficient is below 75 ppm·°C-1 from room temperature to its glass transition temperature (Tg), which is crucial to build minute thermal stress during the printing process.

  2. The Extended-OPQ Method for User-Centered Quality of Experience Evaluation: A Study for Mobile 3D Video Broadcasting over DVB-H

    Directory of Open Access Journals (Sweden)

    Jumisko-Pyykkö Satu

    2011-01-01

    Full Text Available Abstract The Open Profiling of Quality (OPQ is a mixed methods approach combining a conventional quantitative psychoperceptual evaluation and qualitative descriptive quality evaluation based on naïve participants' individual vocabulary. The method targets evaluation of heterogeneous and multimodal stimulus material. The current OPQ data collection procedure provides a rich pool of data, but full benefit of it has neither been taken in the analysis to build up completeness in understanding the phenomenon under the study nor has the procedure in the analysis been probed with alternative methods. The goal of this paper is to extend the original OPQ method with advanced research methods that have become popular in related research and the component model to be able to generalize individual attributes into a terminology of Quality of Experience. We conduct an extensive subjective quality evaluation study for 3D video on mobile device with heterogeneous stimuli. We vary factors on content, media (coding, concealments, and slice modes, and transmission levels (channel loss rate. The results showed that advanced procedures in the analysis cannot only complement each other but also draw deeper understanding on Quality of Experience.

  3. Evaluation of New Thermally Conductive Geopolymer in Thermal Energy Storage

    Science.gov (United States)

    Černý, Matěj; Uhlík, Jan; Nosek, Jaroslav; Lachman, Vladimír; Hladký, Radim; Franěk, Jan; Brož, Milan

    This paper describes an evaluation of a newly developed thermally conductive geopolymer (TCG), consisting of a mixture of sodium silicate and carbon micro-particles. The TCG is intended to be used as a component of high temperature energy storage (HTTES) to improve its thermal diffusivity. Energy storage is crucial for both ecological and economical sustainability. HTTES plays a vital role in solar energy technologies and in waste heat recovery. The most advanced HTTES technologies are based on phase change materials or molten salts, but suffer with economic and technological limitations. Rock or concrete HTTES are cheaper, but they have low thermal conductivity without incorporation of TCG. It was observed that TCG is stable up to 400 °C. The thermal conductivity was measured in range of 20-23 W m-1 K-1. The effect of TCG was tested by heating a granite block with an artificial fissure. One half of the fissure was filled with TCG and the other with ballotini. 28 thermometers, 5 dilatometers and strain sensors were installed on the block. The heat transport experiment was evaluated with COMSOL Multiphysics software.

  4. Study of hybrid laser / MAG welding process: characterization of the geometry and the hydrodynamics of the melt pool and development of a 3D thermal model

    International Nuclear Information System (INIS)

    Hybrid laser/MIG-MAG welding shows high advantages compared to laser welding or GMAW arc welding used separately. Thanks to this process, higher productivity can be gained through higher welding speed, higher squeeze tolerance moreover possible improvement of the metallurgical properties of the weld seam can be obtained. However, many operating parameters have to be set up in order to achieve optimal process. The complex physical phenomena, which govern welding process, have to be understood in order to use efficiently this technique in mass production. Understanding of these phenomena is also necessary to program numerical simulations which fit to this process. In the first step, experimental studies have been carried out with GMAW, laser and hybrid welding on samples of S355 steel. Influence of operating parameters has been analyzed through films performed with speed camera and macro-graphies of weld seam cross section. Surface deformations of the melt pool, induced by the arc pressure, weld pool length, droplet detachment and welding speed, have been analyzed precisely from images of the surface melt pool. In a second step, a numerical model was developed using the COMSOL Multiphysics software for MAG, laser and hybrid laser/MAG welding processes. A 3D quasi-stationary model has been calculated from the temperature field within the metal. The originality of the MAG and hybrid model lies in the prediction of the melt pool surface profile used to determine the 3D geometry, by taking into account the material input. The influence of different parameters such as arc power and speed welding on the efficiency as well as the distribution radius of the arc power and the arc pressure are analyzed through validations with different experimental results and different calculation configurations. (author)

  5. Evaluation of anti-HER2 scFv-conjugated PLGA-PEG nanoparticles on 3D tumor spheroids of BT474 and HCT116 cancer cells

    Science.gov (United States)

    Thuy Duong Le, Thi; Pham, Thu Hong; Nghia Nguyen, Trong; Giang Ngo, Thi Hong; Nhung Hoang, Thi My; Huan Le, Quang

    2016-06-01

    Three-dimensional culture cells (spheroids) are one of the multicellular culture models that can be applied to anticancer chemotherapeutic development. Multicellular spheroids more closely mimic in vivo tumor-like patterns of physiologic environment and morphology. In previous research, we designed docetaxel-loaded pegylated poly(D, L-lactide-co-glycolide) nanoparticles conjugated with anti-HER2 single chain antibodies (scFv-Doc-PLGA-PEG) and evaluated them in 2D cell culture. In this study, we continuously evaluate the cellular uptake and cytotoxic effect of scFv-Doc-PLGA-PEG on a 3D tumor spheroid model of BT474 (HER2-overexpressing) and HCT116 (HER2-underexpressing) cancer cells. The results showed that the nanoparticle formulation conjugated with scFv had a significant internalization effect on the spheroids of HER2-overexpressing cancer cells as compared to the spheroids of HER2-underexpressing cancer cells. Therefore, cytotoxic effects of targeted nanoparticles decreased the size and increased necrotic score of HER2-overexpressing tumor spheroids. Thus, these scFv-Doc-PLGA-PEG nanoparticles have potential for active targeting for HER2-overexpressing cancer therapy. In addition, BT474 and HCT116 spheroids can be used as a tumor model for evaluation of targeting therapies.

  6. Evaluation of the quantitative accuracy of 3D reconstruction of edentulous jaw models with jaw relation based on reference point system alignment.

    Directory of Open Access Journals (Sweden)

    Weiwei Li

    Full Text Available OBJECTIVES: To apply contact measurement and reference point system (RPS alignment techniques to establish a method for 3D reconstruction of the edentulous jaw models with centric relation and to quantitatively evaluate its accuracy. METHODS: Upper and lower edentulous jaw models were clinically prepared, 10 pairs of resin cylinders with same size were adhered to axial surfaces of upper and lower models. The occlusal bases and the upper and lower jaw models were installed in the centric relation position. Faro Edge 1.8m was used to directly obtain center points of the base surface of the cylinders (contact method. Activity 880 dental scanner was used to obtain 3D data of the cylinders and the center points were fitted (fitting method. 3 pairs of center points were used to align the virtual model to centric relation. An observation coordinate system was interactively established. The straight-line distances in the X (horizontal left/right, Y (horizontal anterior/posterior, and Z (vertical between the remaining 7 pairs of center points derived from contact method and fitting method were measured respectively and analyzed using a paired t-test. RESULTS: The differences of the straight-line distances of the remaining 7 pairs of center points between the two methods were X: 0.074 ± 0.107 mm, Y: 0.168 ± 0.176 mm, and Z: -0.003± 0.155 mm. The results of paired t-test were X and Z: p >0.05, Y: p <0.05. CONCLUSION: By using contact measurement and the reference point system alignment technique, highly accurate reconstruction of the vertical distance and centric relation of a digital edentulous jaw model can be achieved, which meets the design and manufacturing requirements of the complete dentures. The error of horizontal anterior/posterior jaw relation was relatively large.

  7. An aerial 3D printing test mission

    Science.gov (United States)

    Hirsch, Michael; McGuire, Thomas; Parsons, Michael; Leake, Skye; Straub, Jeremy

    2016-05-01

    This paper provides an overview of an aerial 3D printing technology, its development and its testing. This technology is potentially useful in its own right. In addition, this work advances the development of a related in-space 3D printing technology. A series of aerial 3D printing test missions, used to test the aerial printing technology, are discussed. Through completing these test missions, the design for an in-space 3D printer may be advanced. The current design for the in-space 3D printer involves focusing thermal energy to heat an extrusion head and allow for the extrusion of molten print material. Plastics can be used as well as composites including metal, allowing for the extrusion of conductive material. A variety of experiments will be used to test this initial 3D printer design. High altitude balloons will be used to test the effects of microgravity on 3D printing, as well as parabolic flight tests. Zero pressure balloons can be used to test the effect of long 3D printing missions subjected to low temperatures. Vacuum chambers will be used to test 3D printing in a vacuum environment. The results will be used to adapt a current prototype of an in-space 3D printer. Then, a small scale prototype can be sent into low-Earth orbit as a 3-U cube satellite. With the ability to 3D print in space demonstrated, future missions can launch production hardware through which the sustainability and durability of structures in space will be greatly improved.

  8. Massive 3D Supergravity

    CERN Document Server

    Andringa, Roel; de Roo, Mees; Hohm, Olaf; Sezgin, Ergin; Townsend, Paul K

    2009-01-01

    We construct the N=1 three-dimensional supergravity theory with cosmological, Einstein-Hilbert, Lorentz Chern-Simons, and general curvature squared terms. We determine the general supersymmetric configuration, and find a family of supersymmetric adS vacua with the supersymmetric Minkowski vacuum as a limiting case. Linearizing about the Minkowski vacuum, we find three classes of unitary theories; one is the supersymmetric extension of the recently discovered `massive 3D gravity'. Another is a `new topologically massive supergravity' (with no Einstein-Hilbert term) that propagates a single (2,3/2) helicity supermultiplet.

  9. Massive 3D supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Andringa, Roel; Bergshoeff, Eric A; De Roo, Mees; Hohm, Olaf [Centre for Theoretical Physics, University of Groningen, Nijenborgh 4, 9747 AG Groningen (Netherlands); Sezgin, Ergin [George and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Townsend, Paul K, E-mail: E.A.Bergshoeff@rug.n, E-mail: O.Hohm@rug.n, E-mail: sezgin@tamu.ed, E-mail: P.K.Townsend@damtp.cam.ac.u [Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WA (United Kingdom)

    2010-01-21

    We construct the N=1 three-dimensional supergravity theory with cosmological, Einstein-Hilbert, Lorentz Chern-Simons, and general curvature squared terms. We determine the general supersymmetric configuration, and find a family of supersymmetric adS vacua with the supersymmetric Minkowski vacuum as a limiting case. Linearizing about the Minkowski vacuum, we find three classes of unitary theories; one is the supersymmetric extension of the recently discovered 'massive 3D gravity'. Another is a 'new topologically massive supergravity' (with no Einstein-Hilbert term) that propagates a single (2,3/2) helicity supermultiplet.

  10. 3D Digital Modelling

    DEFF Research Database (Denmark)

    Hundebøl, Jesper

    ABSTRACT: Lack of productivity in construction is a well known issue. Despite the fact that causes hereof are multiple, the introduction of information technology is a frequently observed response to almost any challenge. ICT in construction is a thoroughly researched matter, however, the current...... important to appreciate the analysis. Before turning to the presentation of preliminary findings and a discussion of 3D digital modelling, it begins, however, with an outline of industry specific ICT strategic issues. Paper type. Multi-site field study...

  11. Quantitative evaluation of ultrasonic wave propagation in inhomogeneous anisotropic austenitic welds using 3D ray tracing method. Numerical and experimental validation

    International Nuclear Information System (INIS)

    Austenitic welds and dissimilar welds are extensively used in primary circuit pipes and pressure vessels in nuclear power plants, chemical industries and fossil fuelled power plants because of their high fracture toughness, resistance to corrosion and creep at elevated temperatures. However, cracks may initiate in these weld materials during fabrication process or stress operations in service. Thus, it is very important to evaluate the structural integrity of these materials using highly reliable non-destructive testing (NDT) methods. Ultrasonic non-destructive inspection of austenitic welds and dissimilar weld components is complicated because of anisotropic columnar grain structure leading to beam splitting and beam deflection. Simulation tools play an important role in developing advanced reliable ultrasonic testing (UT) techniques and optimizing experimental parameters for inspection of austenitic welds and dissimilar weld components. The main aim of the thesis is to develop a 3D ray tracing model for quantitative evaluation of ultrasonic wave propagation in an inhomogeneous anisotropic austenitic weld material. Inhomogenity in the anisotropic weld material is represented by discretizing into several homogeneous layers. According to ray tracing model, ultrasonic ray paths are traced during its energy propagation through various discretized layers of the material and at each interface the problem of reflection and transmission is solved. The influence of anisotropy on ultrasonic reflection and transmission behaviour in an anisotropic austenitic weld material are quantitatively analyzed in three dimensions. The ultrasonic beam directivity in columnar grained austenitic steel material is determined three dimensionally using Lamb's reciprocity theorem. The developed ray tracing model evaluates the transducer excited ultrasonic fields accurately by taking into account the directivity of the transducer, divergence of the ray bundle, density of rays and phase

  12. 基于 PDMS 的三维电缆设计方法在火力发电厂的应用%3D Cable Design for Thermal Power Plants Based on the PDMS

    Institute of Scientific and Technical Information of China (English)

    王继洋

    2016-01-01

    依据对 PDMS 软件多年的应用经验,结合俄罗斯特洛伊茨克项目,介绍了 PDMS 软件在火力发电厂三维电缆设计方面的应用情况。%Based on application experience of PDMS for many years,combined with TROITSKGRES project,the application of 3D cable design In the thermal power plant with PDMS software are introduced.

  13. TOWARDS: 3D INTERNET

    Directory of Open Access Journals (Sweden)

    Ms. Swapnali R. Ghadge

    2013-08-01

    Full Text Available In today’s ever-shifting media landscape, it can be a complex task to find effective ways to reach your desired audience. As traditional media such as television continue to lose audience share, one venue in particular stands out for its ability to attract highly motivated audiences and for its tremendous growth potential the 3D Internet. The concept of '3D Internet' has recently come into the spotlight in the R&D arena, catching the attention of many people, and leading to a lot of discussions. Basically, one can look into this matter from a few different perspectives: visualization and representation of information, and creation and transportation of information, among others. All of them still constitute research challenges, as no products or services are yet available or foreseen for the near future. Nevertheless, one can try to envisage the directions that can be taken towards achieving this goal. People who take part in virtual worlds stay online longer with a heightened level of interest. To take advantage of that interest, diverse businesses and organizations have claimed an early stake in this fast-growing market. They include technology leaders such as IBM, Microsoft, and Cisco, companies such as BMW, Toyota, Circuit City, Coca Cola, and Calvin Klein, and scores of universities, including Harvard, Stanford and Penn State.

  14. Thin slice three dimentional (3D reconstruction versus CT 3D reconstruction of human breast cancer

    Directory of Open Access Journals (Sweden)

    Yi Zhang

    2013-01-01

    Full Text Available Background & objectives: With improvement in the early diagnosis of breast cancer, breast conserving therapy (BCT is being increasingly used. Precise preoperative evaluation of the incision margin is, therefore, very important. Utilizing three dimentional (3D images in a preoperative evaluation for breast conserving surgery has considerable significance, but the currently 3D CT scan reconstruction commonly used has problems in accurately displaying breast cancer. Thin slice 3D reconstruction is also widely used now to delineate organs and tissues of breast cancers. This study was aimed to compare 3D CT with thin slice 3D reconstruction in breast cancer patients to find a better technique for accurate evaluation of breast cancer. Methods: A total of 16-slice spiral CT scans and 3D reconstructions were performed on 15 breast cancer patients. All patients had been treated with modified radical mastectomy; 2D and 3D images of breast and tumours were obtained. The specimens were fixed and sliced at 2 mm thickness to obtain serial thin slice images, and reconstructed using 3D DOCTOR software to gain 3D images. Results: Compared with 2D CT images, thin slice images showed more clearly the morphological characteristics of tumour, breast tissues and the margins of different tissues in each slice. After 3D reconstruction, the tumour shapes obtained by the two reconstruction methods were basically the same, but the thin slice 3D reconstruction showed the tumour margins more clearly. Interpretation & conclusions: Compared with 3D CT reconstruction, thin slice 3D reconstruction of breast tumour gave clearer images, which could provide guidance for the observation and application of CT 3D reconstructed images and contribute to the accurate evaluation of tumours using CT imaging technology.

  15. Evaluation of left atrial function by multidetector computed tomography before left atrial radiofrequency-catheter ablation: Comparison of a manual and automated 3D volume segmentation method

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, Florian, E-mail: florian.wolf@meduniwien.ac.a [Department of Radiology, Medical University of Vienna, Vienna (Austria); Ourednicek, Petr [Philips Medical Systems, Prague (Czech Republic); Loewe, Christian [Department of Radiology, Medical University of Vienna, Vienna (Austria); Richter, Bernhard; Goessinger, Heinz David; Gwechenberger, Marianne [Department of Cardiology, Medical University of Vienna, Vienna (Austria); Plank, Christina; Schernthaner, Ruediger Egbert; Toepker, Michael; Lammer, Johannes [Department of Radiology, Medical University of Vienna, Vienna (Austria); Feuchtner, Gudrun M. [Department of Radiology, Innsbruck Medical University, Innsbruck (Austria); Institute of Diagnostic Radiology, University Hospital Zurich (Switzerland)

    2010-08-15

    Introduction: The purpose of this study was to compare a manual and automated 3D volume segmentation tool for evaluation of left atrial (LA) function by 64-slice multidetector-CT (MDCT). Methods and materials: In 33 patients with paroxysmal atrial fibrillation a MDCT scan was performed before radiofrequency-catheter ablation. Atrial function (minimal volume (LAmin), maximal volume (LAmax), stroke volume (SV), ejection fraction (EF)) was evaluated by two readers using a manual and an automatic tool and measurement time was evaluated. Results: Automated LA volume segmentation failed in one patient due to low LA enhancement (103HU). Mean LAmax, LAmin, SV and EF were 127.7 ml, 93 ml, 34.7 ml, 27.1% by the automated, and 122.7 ml, 89.9 ml, 32.8 ml, 26.3% by the manual method with no significant difference (p > 0.05) and high Pearsons correlation coefficients (r = 0.94, r = 0.94, r = 0.82 and r = 0.85, p < 0.0001), respectively. The automated method was significantly faster (p < 0.001). Interobserver variability was low for both methods with Pearson's correlation coefficients between 0.98 and 0.99 (p < 0.0001). Conclusions: Evaluation of LA volume and function with 64-slice MDCT is feasible with a very low interobserver variability. The automatic method is as accurate as the manual method but significantly less time consuming permitting a routine use in clinical practice before RF-catheter ablation.

  16. Evaluated neutron data for thermal reactor calculations

    International Nuclear Information System (INIS)

    The paper describes a library of evaluated neutron data designed for thermal reactor calculations and other low energy neutron physics applications. The name of the library is KORT (Evaluated Thermal Reactor Constants). The following information is given in KORT: a general characterization of the nucleus (mass, energy of capture and fission reactions, parameters of radioactive decay); partial cross-sections for neutrons of thermal energy, and the number of secondary fission neutrons (estimated errors in the measurements of these quantities are indicated); coefficients defining the deviation of capture and fission cross-sections from the 1/v law in a Maxwellian spectrum; resonance capture and fission integrals and the estimated errors in these quantities (for nuclei with Z>=90); detailed energy dependence of the cross-sections in the 10-4-5 eV region at T=300 K

  17. 3D hydro-mechanical scenario analysis to evaluate changes of the recent stress field as a result of geological CO2 storage

    Science.gov (United States)

    Magri, Fabien; Tillner, Elena; Kempka, Thomas; Wang, Wenqing; Watanabe, Norihiro; Zimmermann, Günter

    2013-04-01

    CO2 storage in deep saline aquifers is one of the strategies used to reduce greenhouse gas emissions into the atmosphere. However, pressure buildup due to the CO2 injection process and subsequent pressure dissipation alter the recent stress field in and around the reservoir. These stress changes may lead to ground uplift, rock fracturing or fault reactivation. In order to study these phenomena by numerical simulations, flow and mechanical equations have to be solved together, requiring a hydro-mechanical coupling. In the present study, a prospective CO2 storage site located in the Northeast German Basin serves as 3D geological framework for a numerical evaluation of deformations and in situ stress changes induced by CO2 injection into the Middle Bunter sandstone. For that purpose, two open-source simulators are coupled: TOUGH2 (Pruess et al., 1999) is applied to calculate reservoir pore pressures which are subsequently transferred into the hydro-geomechanical simulator OpenGeoSys (Wang et al., 2009) to solve the hydro-mechanical equations. A scenario analysis was undertaken to evaluate the mechanical effects of CO2 injection on the reservoir and caprock stability. The results show that under specific assumptions the vertical movement of the top reservoir is negligible. Furthermore, the changes in the recent stress field predicted by geomechanical modeling are limited to the surrounding of the injection well and not significant enough to endanger the mechanical stability of the reservoir and caprock considering the geological boundary conditions of the study area and the proposed injection scheme The presented study demonstrates the hydro-mechanical effects of CO2 storage in a well-constrained 3D geological regional-scale model based on the characterization of residual rocks, and can therefore be representative for CO2 storage in the Northeast German Basin. References Pruess, K., C.M. Oldenburg, and G. Moridis, "TOUGH2 User's Guide, Version 2.0", Lawrence Berkeley

  18. Virtual Realization using 3D Password

    Directory of Open Access Journals (Sweden)

    A.B.Gadicha

    2012-03-01

    Full Text Available Current authentication systems suffer from many weaknesses. Textual passwords are commonly used; however, users do not follow their requirements. Users tend to choose meaningful words from dictionaries, which make textual passwords easy to break and vulnerable to dictionary or brute force attacks. Many available graphical passwords have a password space that is less than or equal to the textual password space. Smart cards or tokens can be stolen. Many biometric authentications have been proposed; however, users tend to resist using biometrics because of their intrusiveness and the effect on their privacy. Moreover, biometrics cannot be revoked. In this paper, we present and evaluate our contribution, i.e., the 3D password. The 3D password is a multifactor authentication scheme. To be authenticated, we present a 3D virtual environment where the user navigates and interacts with various objects. The sequence of actions and interactions toward the objects inside the 3D environment constructs the user’s 3D password. The 3D password can combine most existing authentication schemes such as textual passwords, graphical passwords, and various types of biometrics into a 3D virtual environment. The design of the 3D virtual environment and the type of objects selected determine the 3D password key space.

  19. Imaging mesenchymal stem cells containing single wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography

    Science.gov (United States)

    Connolly, Emma; Subhash, Hrebesh M.; Leahy, Martin; Rooney, Niall; Barry, Frank; Murphy, Mary; Barron, Valerie

    2014-02-01

    Despite the fact, that a range of clinically viable imaging modalities, such as magnetic resonance imaging (MRI), computed tomography (CT), photo emission tomography (PET), ultrasound and bioluminescence imaging are being optimised to track cells in vivo, many of these techniques are subject to limitations such as the levels of contrast agent required, toxic effects of radiotracers, photo attenuation of tissue and backscatter. With the advent of nanotechnology, nanoprobes are leading the charge to overcome these limitations. In particular, single wall nanotubes (SWNT) have been shown to be taken up by cells and as such are effective nanoprobes for cell imaging. Consequently, the main aim of this research is to employ mesenchymal stem cells (MSC) containing SWNT nanoprobes to image cell distribution in a 3D scaffold for cartilage repair. To this end, MSC were cultured in the presence of 32μg/ml SWNT in cell culture medium (αMEM, 10% FBS, 1% penicillin/streptomycin) for 24 hours. Upon confirmation of cell viability, the MSC containing SWNT were encapsulated in hyaluronic acid gels and loaded on polylactic acid polycaprolactone scaffolds. After 28 days in complete chondrogenic medium, with medium changes every 2 days, chondrogenesis was confirmed by the presence of glycosaminoglycan. Moreover, using photothermal optical coherence tomography (PT-OCT), the cells were seen to be distributed through the scaffold with high resolution. In summary, these data reveal that MSC containing SWNT nanoprobes in combination with PT-OCT offer an exciting opportunity for stem cell tracking in vitro for assessing seeding scaffolds and in vivo for determining biodistribution.

  20. A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT). Part II: On 3D model accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Liang Xin, E-mail: Xin.Liang@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); College of Stomatology, Dalian Medical University (China); Lambrichts, Ivo, E-mail: Ivo.Lambrichts@uhasselt.b [Department of Basic Medical Sciences, Histology and Electron Microscopy, Faculty of Medicine, University of Hasselt, Diepenbeek (Belgium); Sun Yi, E-mail: Sunyihello@hotmail.co [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Denis, Kathleen, E-mail: kathleen.denis@groept.b [Department of Industrial Sciences and Techology-Engineering (IWT), XIOS Hogeschool Limburg, Hasselt (Belgium); Hassan, Bassam, E-mail: b.hassan@acta.n [Department of Oral Radiology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam (Netherlands); Li Limin, E-mail: Limin.Li@uz.kuleuven.b [Department of Paediatric Dentistry and Special Dental Care, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Pauwels, Ruben, E-mail: Ruben.Pauwels@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Jacobs, Reinhilde, E-mail: Reinhilde.Jacobs@uz.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium)

    2010-08-15

    Aim: The study aim was to compare the geometric accuracy of three-dimensional (3D) surface model reconstructions between five Cone Beam Computed Tomography (CBCT) scanners and one Multi-Slice CT (MSCT) system. Materials and methods: A dry human mandible was scanned with five CBCT systems (NewTom 3G, Accuitomo 3D, i-CAT, Galileos, Scanora 3D) and one MSCT scanner (Somatom Sensation 16). A 3D surface bone model was created from the six systems. The reference (gold standard) 3D model was obtained with a high resolution laser surface scanner. The 3D models from the five systems were compared with the gold standard using a point-based rigid registration algorithm. Results: The mean deviation from the gold standard for MSCT was 0.137 mm and for CBCT were 0.282, 0.225, 0.165, 0.386 and 0.206 mm for the i-CAT, Accuitomo, NewTom, Scanora and Galileos, respectively. Conclusion: The results show that the accuracy of CBCT 3D surface model reconstructions is somewhat lower but acceptable comparing to MSCT from the gold standard.

  1. Evaluation of potential human health effects associated with the agricultural uses of 1,3-D: Spatial and temporal stochastic risk analysis.

    Science.gov (United States)

    Driver, Jeffrey H; Price, Paul S; Van Wesenbeeck, Ian; Ross, John H; Gehen, Sean; Holden, Larry R; Landenberger, Bryce; Hastings, Kerry; Yan, Zhongyu June; Rasoulpour, Reza

    2016-11-15

    Dow AgroSciences (DAS) markets and sells 1,3-Dichloropropene (1,3-D), the active ingredient in Telone®, which is used as a pre-plant soil fumigant nematicide in economically important crops in California. 1,3-D has been regulated as a "probable human carcinogen" and the California Department of Pesticide Regulation limits use of 1,3-D based on human health risk assessments for bystanders. This paper presents a risk characterization for bystanders based on advances in the assessment of both exposure and hazard. The revised bystander risk assessment incorporates significant advances: 1) new data on residency duration and mobility in communities where 1,3-D is in high demand; 2) new information on spatial and temporal concentrations of 1,3-D in air based on multi-year modeling using a validated model; and 3) a new stochastic spatial and temporal model of long-term exposures. Predicted distributions of long-term, chronic exposures indicate that current, and anticipated uses of 1,3-D would result in lifetime average daily doses lower than 0.002mg/kg/d, a dose associated with theoretical lifetime excess cancer risk of 95% of the local population based on a non-threshold risk assessment approach. Additionally, examination of 1,3-D toxicity studies including new chronic toxicity data and mechanism of action supports the use of a non-linear, threshold based risk assessment approach. The estimated maximum annual average daily dose of 1000-fold, a clear indication of acceptable risk for human health. In summary, the best available science supports 1,3-D's threshold nature of hazard and the revised exposure assessment supports that current agricultural uses of 1,3-D are associated with reasonable certainty of no harm, i.e., estimated long-term exposures pose insignificant health risks to bystanders even when the non-threshold approach is assumed.

  2. Design and Evaluation of a Fiber-Optic Grip Force Sensor with Compliant 3D-Printable Structure for (fMRI Applications

    Directory of Open Access Journals (Sweden)

    Tobias L. Bützer

    2016-01-01

    Full Text Available Grip force sensors compatible with magnetic resonance imaging (MRI are used in human motor control and decision-making research, providing objective and sensitive behavioral outcome measures. Commercial sensors are expensive, cover limited force ranges, rely on pneumatic force transmission that cannot detect fast force changes, or are electrically active, which increases the risk of electromagnetic interference. We present the design and evaluation of a low-cost, 3D-printed, inherently MRI-compatible grip force sensor based on a commercial intensity-based fiber-optic sensor. A compliant monobloc structure with flexible hinges transduces grip force to a linear displacement captured by the fiber-optic sensor. The structure can easily be adapted for different force ranges by changing the hinge thickness. A prototype designed for forces up to 800 N was manufactured and showed a highly linear behavior (nonlinearity of 2.37% and an accuracy of 1.57% in a range between zero and 500 N. It can be printed and assembled within one day and for less than $300. Accurate performance was confirmed, both inside and outside a 3 T MRI scanner within a pilot study. Given its simple design allowing for customization of sensing properties and ergonomics for different applications and requirements, the proposed grip force handle offers researchers a valuable scientific tool.

  3. Evaluation of serum immonogiobulins (A,G,M and complement components (C3 d in Isfahan dental clinics patients with recurrent aphlus stomatitis

    Directory of Open Access Journals (Sweden)

    Ghalayani Isfahani P

    2000-06-01

    Full Text Available Recurrent aphtus stomatitis (RAS is an oral mucous lesion in patients with no other signs of disease. Investigators have always notified the role of immune system especially humoral immunity in aphtus immunopathogenesis. The aim of this case-controlled study was to measure amount of serum immonogiobulins (A,G,M and complement component (C3 d in patients with RAS and to evaluate any relation between differences in these factors and pathogenesis of RAS. Immonogiobulins (A,G,M and complement components (C3 Ci of 50 patients with RAS was measured using single radial immuno diffusion technique. The results were compared with immonogiobulins (A,G,M and complement components (C3 Cj of 50 healthy people whom were similar in age and sex with the patients group. Results showed that the patients group had higher level of IgA and IgM while serum lgG was similar in both groups. The C$ was lower in aphtus patients while no significant difference was found in amount of C,|. The sex had no significant effect on serum level of measured factors. From the results it can be concluded that the humoral immunity reaction has an important role in immunopathogenesis of RAS. This humoral response might accurse as a result of cellular immunity reaction.

  4. 3D nanocomposite chitosan/bioactive glass scaffolds obtained using two different routes: an evaluation of the porous structure and mechanical properties

    Directory of Open Access Journals (Sweden)

    Elke M. F. Lemos

    2016-05-01

    Full Text Available Porous synthetic substrates are developed through tissue engineering technologies to grow new tissue, restoring the function of tissue or an organ. For bone regeneration, these scaffolds must support the dynamic load exerted on this tissue, achieved primarily by increasing their compression strength, as established in the literature. The aim of this paper was to incorporate an inorganic composite bioactive glass (60%SiO2 - 36%CaO - 4%P2O5 as a reinforcing agent in mechanical 3D scaffolds that must remain porous. Two strategies were adopted: a co-precipitation method to obtain a nanoparticulate dispersion of bioactive glass (BGNP and a sol-gel method to combine a bioactive glass solution (BG with a previously prepared chitosan polymer solution. Moreover, a lyophilization process was also used, generating highly porous scaffolds. Various aspects of the scaffold were evaluated, including the morphology, orientation and size of the pores, and mechanical strength, as obtained using the two synthetic methods. The data for compressive strength revealed increased strength after the incorporation of bioactive glass, which was more pronounced when utilizing the nanoscale bioactive glass.

  5. The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation.

    Science.gov (United States)

    Ma, Ying; Jin, Yuan-Yuan; Wang, Ye-Liu; Wang, Run-Ling; Lu, Xin-Hua; Kong, De-Xin; Xu, Wei-Ren

    2014-06-01

    Given the special role of insulin and leptin signaling in various biological responses, protein-tyrosine phosphatase-1B (PTP1B) was regarded as a novel therapeutic target for treating type 2 diabetes and obesity. However, owing to the highly conserved (sequence identity of about 74%) in active pocket, targeting PTP1B for drug discovery is a great challenge. In this study, we employed the software package Discovery Studio to develop 3D QSAR pharmacophore models for PTP1B and TCPTP inhibitors. It was further validated by three methods (cost analysis, test set prediction, and Fisher's test) to show that the models can be used to predict the biological activities of compounds without costly and time-consuming synthesis. The criteria for virtual screening were also validated by testing the selective PTP1B inhibitors. Virtual screening experiments and subsequent in vitro evaluation of promising hits revealed a novel and selective inhibitor of PTP1B over TCPTP. After that, a most likely binding mode was proposed. Thus, the findings reported here may provide a new strategy in discovering selective PTP1B inhibitors.

  6. Synthesis, antitumor evaluation and 3D-QSAR studies of [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives.

    Science.gov (United States)

    Xu, Feng; Yang, Zhen-Zhen; Ke, Zhong-Lu; Xi, Li-Min; Yan, Qi-Dong; Yang, Wei-Qiang; Zhu, Li-Qing; Lin, Fei-Lei; Lv, Wei-Ke; Wu, Han-Gui; Wang, John; Li, Hai-Bo

    2016-10-01

    A series of [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives have been synthesized and their structures were confirmed by single-crystal X-ray diffraction. Compared to some reported structures of 1,6-dihydro-1,2,4,5-tetrazine, these compounds can't be considered as having homoaromaticity. Their antiproliferative activities were evaluated against MCF-7, Bewo and HL-60 cells in vitro. Two compounds were highly effective against MCF-7, Bewo and HL-60 cells with IC50 values in 0.63-13.12μM. Three-dimensional quantitative structure-activity relationship (3D-QSAR) studies of comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were carried out on 51 [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives with antiproliferative activity against MCF-7 cell. Models with good predictive abilities were generated with the cross validated q(2) values for CoMFA and CoMSIA being 0.716 and 0.723, respectively. Conventional r(2) values were 0.985 and 0.976, respectively. The results provide the tool for guiding the design and synthesis of novel and more potent tetrazine derivatives. PMID:27597251

  7. 3D J-Integral Capability in Grizzly

    Energy Technology Data Exchange (ETDEWEB)

    Benjamin Spencer; Marie Backman; Pritam Chakraborty; William Hoffman

    2014-09-01

    This report summarizes work done to develop a capability to evaluate fracture contour J-Integrals in 3D in the Grizzly code. In the current fiscal year, a previously-developed 2D implementation of a J-Integral evaluation capability has been extended to work in 3D, and to include terms due both to mechanically-induced strains and due to gradients in thermal strains. This capability has been verified against a benchmark solution on a model of a curved crack front in 3D. The thermal term in this integral has been verified against a benchmark problem with a thermal gradient. These developments are part of a larger effort to develop Grizzly as a tool that can be used to predict the evolution of aging processes in nuclear power plant systems, structures, and components, and assess their capacity after being subjected to those aging processes. The capabilities described here have been developed to enable evaluations of Mode- stress intensity factors on axis-aligned flaws in reactor pressure vessels. These can be compared with the fracture toughness of the material to determine whether a pre-existing flaw would begin to propagate during a pos- tulated pressurized thermal shock accident. This report includes a demonstration calculation to show how Grizzly is used to perform a deterministic assessment of such a flaw propagation in a degraded reactor pressure vessel under pressurized thermal shock conditions. The stress intensity is calculated from J, and the toughness is computed using the fracture master curve and the degraded ductile to brittle transition temperature.

  8. Wireless 3D Chocolate Printer

    Directory of Open Access Journals (Sweden)

    FROILAN G. DESTREZA

    2014-02-01

    Full Text Available This study is for the BSHRM Students of Batangas State University (BatStateU ARASOF for the researchers believe that the Wireless 3D Chocolate Printer would be helpful in their degree program especially on making creative, artistic, personalized and decorative chocolate designs. The researchers used the Prototyping model as procedural method for the successful development and implementation of the hardware and software. This method has five phases which are the following: quick plan, quick design, prototype construction, delivery and feedback and communication. This study was evaluated by the BSHRM Students and the assessment of the respondents regarding the software and hardware application are all excellent in terms of Accuracy, Effecitveness, Efficiency, Maintainability, Reliability and User-friendliness. Also, the overall level of acceptability of the design project as evaluated by the respondents is excellent. With regard to the observation about the best raw material to use in 3D printing, the chocolate is good to use as the printed material is slightly distorted,durable and very easy to prepare; the icing is also good to use as the printed material is not distorted and is very durable but consumes time to prepare; the flour is not good as the printed material is distorted, not durable but it is easy to prepare. The computation of the economic viability level of 3d printer with reference to ROI is 37.14%. The recommendation of the researchers in the design project are as follows: adding a cooling system so that the raw material will be more durable, development of a more simplified version and improving the extrusion process wherein the user do not need to stop the printing process just to replace the empty syringe with a new one.

  9. 3-D thermal analysis using finite difference technique with finite element model for improved design of components of rocket engine turbomachines for Space Shuttle Main Engine SSME

    Science.gov (United States)

    Sohn, Kiho D.; Ip, Shek-Se P.

    1988-01-01

    Three-dimensional finite element models were generated and transferred into three-dimensional finite difference models to perform transient thermal analyses for the SSME high pressure fuel turbopump's first stage nozzles and rotor blades. STANCOOL was chosen to calculate the heat transfer characteristics (HTCs) around the airfoils, and endwall effects were included at the intersections of the airfoils and platforms for the steady-state boundary conditions. Free and forced convection due to rotation effects were also considered in hollow cores. Transient HTCs were calculated by taking ratios of the steady-state values based on the flow rates and fluid properties calculated at each time slice. Results are presented for both transient plots and three-dimensional color contour isotherm plots; they were also converted into universal files to be used for FEM stress analyses.

  10. Evaluation of brain perfusion in specific Brodmann areas in Frontotemporal dementia and Alzheimer disease using automated 3-D voxel based analysis

    Energy Technology Data Exchange (ETDEWEB)

    Valotassiou, V; Tsougos, I; Tzavara, C; Georgoulias, P [Nuclear Medicine Dpt, University Hospital of Larissa, Larissa (Greece); Papatriantafyllou, J; Karageorgiou, C [Neurology Dpt, General Hospital ' G. Gennimatas' , Athens (Greece); Sifakis, N; Zerva, C [Nuclear Medicine Dpt, ' Alexandra' University Hospital, Athens (Greece)], E-mail: vanvalot@yahoo.gr

    2009-05-15

    Introduction. Brain perfusion studies with single-photon emission computed tomography (SPECT) have been applied in demented patients to provide better discrimination between frontotemporal dementia (FTD) and Alzheimer's disease (AD). Aim. To assess the perfusion of specific Brodmann (Br) areas of the brain cortex in FTD and AD patients, using NeuroGam processing program to provide 3D voxel-by-voxel cerebral SPECT analysis. Material and methods. We studied 34 consecutive patients. We used the established criteria for the diagnosis of dementia and the specific established criteria for the diagnosis of FTD and AD. All the patients had a neuropsychological evaluation with a battery of tests including the mini-mental state examination (MMSE).Twenty-six patients (16 males, 10 females, mean age 68.76{+-}6.51 years, education 11.81{+-}4.25 years, MMSE 16.69{+-}9.89) received the diagnosis of FTD and 8 patients (all females, mean age 71.25{+-}10.48 years, education 10{+-}4.6 years, MMSE 12.5{+-}3.89) the diagnosis of AD. All the patients underwent a brain SPECT. We applied the NeuroGam Software for the evaluation of brain perfusion in specific Br areas in the left (L) and right (R) hemispheres. Results. Statistically significant hypoperfusion in FTD compared to AD patients, was found in the following Br areas: 11L (p<0.0001), 11R, 20L, 20R, 32L, 38L, 38R, 44L (p<0.001), 32R, 36L, 36R, 45L, 45R, 47R (p<0.01), 9L, 21L, 39R, 44R, 46R, 47L (p<0.05). On the contrary, AD patients presented significant (p<0.05) hypoperfusion in 7R and 39R Br areas. Conclusion. NeuroGam processing program of brain perfusion SPECT could result in enhanced accuracy for the differential diagnosis between AD and FTD patients.

  11. 3D printing for dummies

    CERN Document Server

    Hausman, Kalani Kirk

    2014-01-01

    Get started printing out 3D objects quickly and inexpensively! 3D printing is no longer just a figment of your imagination. This remarkable technology is coming to the masses with the growing availability of 3D printers. 3D printers create 3-dimensional layered models and they allow users to create prototypes that use multiple materials and colors.  This friendly-but-straightforward guide examines each type of 3D printing technology available today and gives artists, entrepreneurs, engineers, and hobbyists insight into the amazing things 3D printing has to offer. You'll discover methods for

  12. Martian terrain - 3D

    Science.gov (United States)

    1997-01-01

    This area of terrain near the Sagan Memorial Station was taken on Sol 3 by the Imager for Mars Pathfinder (IMP). 3D glasses are necessary to identify surface detail.The IMP is a stereo imaging system with color capability provided by 24 selectable filters -- twelve filters per 'eye.' It stands 1.8 meters above the Martian surface, and has a resolution of two millimeters at a range of two meters.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.Click below to see the left and right views individually. [figure removed for brevity, see original site] Left [figure removed for brevity, see original site] Right

  13. 3D monitor

    OpenAIRE

    Szkandera, Jan

    2009-01-01

    Tato bakalářská práce se zabývá návrhem a realizací systému, který umožní obraz scény zobrazovaný na ploše vnímat prostorově. Prostorové vnímání 2D obrazové informace je umožněno jednak stereopromítáním a jednak tím, že se obraz mění v závislosti na poloze pozorovatele. Tato práce se zabývá hlavně druhým z těchto problémů. This Bachelor's thesis goal is to design and realize system, which allows user to perceive 2D visual information as three-dimensional. 3D visual preception of 2D image i...

  14. Thermal processes evaluation for RWMC wastes

    International Nuclear Information System (INIS)

    The objective of this activity was to provide a white paper that identifies, collects information, and presents a preliminary evaluation of ''core'' thermal technologies that could be applied to RWMC stored and buried mixed waste. This paper presents the results of the following activities: General thermal technology identification, collection of technical and cost information on each technology, identification of thermal technologies applicable to RWMC waste, evaluation of each technology as applied to RWMC waste in seven process attributes, scoring each technology on a one to five scale (five highest) in each process attribute. Reaching conclusions about the superiority of one technology over others is not advised based on this preliminary study alone. However, the highly rated technologies (i.e., overall score of 2.9 or better) are worthy of a more detailed evaluation. The next step should be a more detailed evaluation of the technologies that includes onsite visits with operational facilities, preconceptual treatment facility design analysis, and visits with developers for emerging technologies. 2 figs., 6 tabs

  15. Evaluation of the scale dependent dynamic SGS model in the open source code caffa3d.MBRi in wall-bounded flows

    Science.gov (United States)

    Draper, Martin; Usera, Gabriel

    2015-04-01

    The Scale Dependent Dynamic Model (SDDM) has been widely validated in large-eddy simulations using pseudo-spectral codes [1][2][3]. The scale dependency, particularly the potential law, has been proved also in a priori studies [4][5]. To the authors' knowledge there have been only few attempts to use the SDDM in finite difference (FD) and finite volume (FV) codes [6][7], finding some improvements with the dynamic procedures (scale independent or scale dependent approach), but not showing the behavior of the scale-dependence parameter when using the SDDM. The aim of the present paper is to evaluate the SDDM in the open source code caffa3d.MBRi, an updated version of the code presented in [8]. caffa3d.MBRi is a FV code, second-order accurate, parallelized with MPI, in which the domain is divided in unstructured blocks of structured grids. To accomplish this, 2 cases are considered: flow between flat plates and flow over a rough surface with the presence of a model wind turbine, taking for this case the experimental data presented in [9]. In both cases the standard Smagorinsky Model (SM), the Scale Independent Dynamic Model (SIDM) and the SDDM are tested. As presented in [6][7] slight improvements are obtained with the SDDM. Nevertheless, the behavior of the scale-dependence parameter supports the generalization of the dynamic procedure proposed in the SDDM, particularly taking into account that no explicit filter is used (the implicit filter is unknown). [1] F. Porté-Agel, C. Meneveau, M.B. Parlange. "A scale-dependent dynamic model for large-eddy simulation: application to a neutral atmospheric boundary layer". Journal of Fluid Mechanics, 2000, 415, 261-284. [2] E. Bou-Zeid, C. Meneveau, M. Parlante. "A scale-dependent Lagrangian dynamic model for large eddy simulation of complex turbulent flows". Physics of Fluids, 2005, 17, 025105 (18p). [3] R. Stoll, F. Porté-Agel. "Dynamic subgrid-scale models for momentum and scalar fluxes in large-eddy simulations of

  16. 3D game environments create professional 3D game worlds

    CERN Document Server

    Ahearn, Luke

    2008-01-01

    The ultimate resource to help you create triple-A quality art for a variety of game worlds; 3D Game Environments offers detailed tutorials on creating 3D models, applying 2D art to 3D models, and clear concise advice on issues of efficiency and optimization for a 3D game engine. Using Photoshop and 3ds Max as his primary tools, Luke Ahearn explains how to create realistic textures from photo source and uses a variety of techniques to portray dynamic and believable game worlds.From a modern city to a steamy jungle, learn about the planning and technological considerations for 3D modelin

  17. X3D: Extensible 3D Graphics Standard

    OpenAIRE

    Daly, Leonard; Brutzman, Don

    2007-01-01

    The article of record as published may be located at http://dx.doi.org/10.1109/MSP.2007.905889 Extensible 3D (X3D) is the open standard for Web-delivered three-dimensional (3D) graphics. It specifies a declarative geometry definition language, a run-time engine, and an application program interface (API) that provide an interactive, animated, real-time environment for 3D graphics. The X3D specification documents are freely available, the standard can be used without paying any royalties,...

  18. Quantitative evaluation of ultrasonic wave propagation in inhomogeneous anisotropic austenitic welds using 3D ray tracing method. Numerical and experimental validation

    Energy Technology Data Exchange (ETDEWEB)

    Kolkoori, Sanjeevareddy

    2014-07-01

    Austenitic welds and dissimilar welds are extensively used in primary circuit pipes and pressure vessels in nuclear power plants, chemical industries and fossil fuelled power plants because of their high fracture toughness, resistance to corrosion and creep at elevated temperatures. However, cracks may initiate in these weld materials during fabrication process or stress operations in service. Thus, it is very important to evaluate the structural integrity of these materials using highly reliable non-destructive testing (NDT) methods. Ultrasonic non-destructive inspection of austenitic welds and dissimilar weld components is complicated because of anisotropic columnar grain structure leading to beam splitting and beam deflection. Simulation tools play an important role in developing advanced reliable ultrasonic testing (UT) techniques and optimizing experimental parameters for inspection of austenitic welds and dissimilar weld components. The main aim of the thesis is to develop a 3D ray tracing model for quantitative evaluation of ultrasonic wave propagation in an inhomogeneous anisotropic austenitic weld material. Inhomogenity in the anisotropic weld material is represented by discretizing into several homogeneous layers. According to ray tracing model, ultrasonic ray paths are traced during its energy propagation through various discretized layers of the material and at each interface the problem of reflection and transmission is solved. The influence of anisotropy on ultrasonic reflection and transmission behaviour in an anisotropic austenitic weld material are quantitatively analyzed in three dimensions. The ultrasonic beam directivity in columnar grained austenitic steel material is determined three dimensionally using Lamb's reciprocity theorem. The developed ray tracing model evaluates the transducer excited ultrasonic fields accurately by taking into account the directivity of the transducer, divergence of the ray bundle, density of rays and phase

  19. 3D Printing an Octohedron

    OpenAIRE

    Aboufadel, Edward F.

    2014-01-01

    The purpose of this short paper is to describe a project to manufacture a regular octohedron on a 3D printer. We assume that the reader is familiar with the basics of 3D printing. In the project, we use fundamental ideas to calculate the vertices and faces of an octohedron. Then, we utilize the OPENSCAD program to create a virtual 3D model and an STereoLithography (.stl) file that can be used by a 3D printer.

  20. Salient Local 3D Features for 3D Shape Retrieval

    CERN Document Server

    Godil, Afzal

    2011-01-01

    In this paper we describe a new formulation for the 3D salient local features based on the voxel grid inspired by the Scale Invariant Feature Transform (SIFT). We use it to identify the salient keypoints (invariant points) on a 3D voxelized model and calculate invariant 3D local feature descriptors at these keypoints. We then use the bag of words approach on the 3D local features to represent the 3D models for shape retrieval. The advantages of the method are that it can be applied to rigid as well as to articulated and deformable 3D models. Finally, this approach is applied for 3D Shape Retrieval on the McGill articulated shape benchmark and then the retrieval results are presented and compared to other methods.

  1. Estimating the relationship between urban 3D morphology and land surface temperature using airborne LiDAR and Landsat-8 Thermal Infrared Sensor data

    Science.gov (United States)

    Lee, J. H.

    2015-12-01

    Urban forests are known for mitigating the urban heat island effect and heat-related health issues by reducing air and surface temperature. Beyond the amount of the canopy area, however, little is known what kind of spatial patterns and structures of urban forests best contributes to reducing temperatures and mitigating the urban heat effects. Previous studies attempted to find the relationship between the land surface temperature and various indicators of vegetation abundance using remote sensed data but the majority of those studies relied on two dimensional area based metrics, such as tree canopy cover, impervious surface area, and Normalized Differential Vegetation Index, etc. This study investigates the relationship between the three-dimensional spatial structure of urban forests and urban surface temperature focusing on vertical variance. We use a Landsat-8 Thermal Infrared Sensor image (acquired on July 24, 2014) to estimate the land surface temperature of the City of Sacramento, CA. We extract the height and volume of urban features (both vegetation and non-vegetation) using airborne LiDAR (Light Detection and Ranging) and high spatial resolution aerial imagery. Using regression analysis, we apply empirical approach to find the relationship between the land surface temperature and different sets of variables, which describe spatial patterns and structures of various urban features including trees. Our analysis demonstrates that incorporating vertical variance parameters improve the accuracy of the model. The results of the study suggest urban tree planting is an effective and viable solution to mitigate urban heat by increasing the variance of urban surface as well as evaporative cooling effect.

  2. 3D modelling and recognition

    OpenAIRE

    Rodrigues, Marcos; Robinson, Alan; Alboul, Lyuba; Brink, Willie

    2006-01-01

    3D face recognition is an open field. In this paper we present a method for 3D facial recognition based on Principal Components Analysis. The method uses a relatively large number of facial measurements and ratios and yields reliable recognition. We also highlight our approach to sensor development for fast 3D model acquisition and automatic facial feature extraction.

  3. mTOR-inhibitor treatment of metastatic renal cell carcinoma: contribution of Choi and modified Choi criteria assessed in 2D or 3D to evaluate tumor response

    Energy Technology Data Exchange (ETDEWEB)

    Lamuraglia, M. [Laboratoire d' Imagerie Biomedicale, Sorbonne Universites, UPMC Univ Paris 06, INSERM, CNRS, Paris (France); Raslan, S.; Penna, R.R.; Wagner, M. [Groupe Hospitalier Pitie-Salpetriere, APHP UPMC, Service de Radiologie Polyvalente et Oncologique, Paris Cedex 13 (France); Elaidi, R.; Oudard, S. [APHP, Oncology Unit, Georges-Pompidou Hospital, Paris (France); Escudier, B. [Gustave-Roussy Institute, Medical Oncology Department, Villejuif (France); Slimane, K. [Novartis Pharma, Rueil-Malmaison (France); Lucidarme, O. [Groupe Hospitalier Pitie-Salpetriere, APHP UPMC, Service de Radiologie Polyvalente et Oncologique, Paris Cedex 13 (France); Laboratoire d' Imagerie Biomedicale, Sorbonne Universites, UPMC Univ Paris 06, INSERM, CNRS, Paris (France)

    2016-01-15

    To determine whether 2D or 3D Choi and modified Choi (mChoi) criteria could assess the efficacy of everolimus against metastatic renal cell carcinoma (mRCC). RECIST-1.1, Choi, and mChoi criteria were applied retrospectively to analyse baseline and 2-month contrast-enhanced computed tomography (CECT) images in 48 patients with mRCC enrolled in the everolimus arm of the French randomized double-blind multicentre phase III trial comparing everolimus versus placebo (RECORD-1). The primary endpoint was centrally reviewed progression-free survival (PFS) calculated from the initial RECORD-1 analysis. Mean attenuation was determined for 2D target lesion regions of interest drawn on CECT sections whose largest diameters had been measured, and for the 3D whole target lesion. The median PFS was 5.5 months. The median PFS for everolimus responders defined using 3D mChoi criteria was significantly longer than for non-responders (7.6 versus 5.4 months, respectively), corresponding to a hazard ratio for progression of 0.45 (95 % CI: 0.22-0.92), with respective 1-year survival rates of 31 % and 9 %. No other 2D or 3D imaging criteria at 2 months identified patients who would benefit from everolimus. At 2 months, only 3D mChoi criteria were able to identify mRCC patients with a PFS benefit from everolimus. (orig.)

  4. Experimental evaluations of the accuracy of 3D and 4D planning in robotic tracking stereotactic body radiotherapy for lung cancers

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Mark K. H. [Department of Clinical Oncology, The University of Hong Kong and Department of Clinical Oncology, Tuen Mun Hospital, Hong Kong Special Administrative Region, 999077 (Hong Kong); Kwong, Dora L. W.; Ng, Sherry C. Y. [Department of Clinical Oncology, Queen Mary Hospital, Hong Kong Special Administrative Region, 999077 (Hong Kong); Tong, Anthony S. M.; Tam, Eric K. W. [Theresa Po CyberKnife Center, Hong Kong Special Administrative Region, 999077 (Hong Kong)

    2013-04-15

    Purpose: Due to the complexity of 4D target tracking radiotherapy, the accuracy of this treatment strategy should be experimentally validated against established standard 3D technique. This work compared the accuracy of 3D and 4D dose calculations in respiration tracking stereotactic body radiotherapy (SBRT). Methods: Using the 4D planning module of the CyberKnife treatment planning system, treatment plans for a moving target and a static off-target cord structure were created on different four-dimensional computed tomography (4D-CT) datasets of a thorax phantom moving in different ranges. The 4D planning system used B-splines deformable image registrations (DIR) to accumulate dose distributions calculated on different breathing geometries, each corresponding to a static 3D-CT image of the 4D-CT dataset, onto a reference image to compose a 4D dose distribution. For each motion, 4D optimization was performed to generate a 4D treatment plan of the moving target. For comparison with standard 3D planning, each 4D plan was copied to the reference end-exhale images and a standard 3D dose calculation was followed. Treatment plans of the off-target structure were first obtained by standard 3D optimization on the end-exhale images. Subsequently, they were applied to recalculate the 4D dose distributions using DIRs. All dose distributions that were initially obtained using the ray-tracing algorithm with equivalent path-length heterogeneity correction (3D{sub EPL} and 4D{sub EPL}) were recalculated by a Monte Carlo algorithm (3D{sub MC} and 4D{sub MC}) to further investigate the effects of dose calculation algorithms. The calculated 3D{sub EPL}, 3D{sub MC}, 4D{sub EPL}, and 4D{sub MC} dose distributions were compared to measurements by Gafchromic EBT2 films in the axial and coronal planes of the moving target object, and the coronal plane for the static off-target object based on the {gamma} metric at 5%/3mm criteria ({gamma}{sub 5%/3mm}). Treatment plans were considered

  5. Thermally-induced single-crystal-to-single-crystal transformations from a 2D two-fold interpenetrating square lattice layer to a 3D four-fold interpenetrating diamond framework and its application in dye-sensitized solar cells.

    Science.gov (United States)

    Gao, Song; Fan, Rui Qing; Wang, Xin Ming; Wei, Li Guo; Song, Yang; Du, Xi; Xing, Kai; Wang, Ping; Yang, Yu Lin

    2016-07-28

    In this work, a rare 2D → 3D single-crystal-to-single-crystal transformation (SCSC) is observed in metal-organic coordination complexes, which is triggered by thermal treatment. The 2D two-fold interpenetrating square lattice layer [Cd(IBA)2]n (1) is irreversibly converted into a 3D four-fold interpenetrating diamond framework {[Cd(IBA)2(H2O)]·2.5H2O}n (2) (HIBA = 4-(1H-imidazol-1-yl)benzoic acid). Consideration is given to these two complexes with different interpenetrating structures and dimensionality, and their influence on photovoltaic properties are studied. Encouraged by the UV-visible absorption and HOMO-LUMO energy states matched for sensitizing TiO2, the two complexes are employed in combination with N719 in dye-sensitized solar cells (DSSCs) to compensate absorption in the ultraviolet and blue-violet region, offset competitive visible light absorption of I3(-) and reducing charge the recombination of injected electrons. After co-sensitization with 1 and 2, the device co-sensitized by 1/N719 and 2/N719 to yield overall efficiencies of 7.82% and 8.39%, which are 19.94% and 28.68% higher than that of the device sensitized only by N719 (6.52%). Consequently, high dimensional interpenetrating complexes could serve as excellent co-sensitizers and have application in DSSCs. PMID:27356177

  6. Feasibility and evaluation of dual-source transmit 3D imaging of the orbits: Comparison to high-resolution conventional MRI at 3T

    Energy Technology Data Exchange (ETDEWEB)

    Seeger, Achim, E-mail: achim.seeger@gmx.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Schulze, Maximilian, E-mail: maximilian.schulze@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Schuettauf, Frank, E-mail: fschuettauf@uni-tuebingen.de [University Eye Hospital, Department of Ophthalmology, Eberhard-Karls-University, Schleichstrasse 12, Tübingen 72076 (Germany); Klose, Uwe, E-mail: uwe.klose@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Ernemann, Ulrike, E-mail: ulrike.ernemann@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany); Hauser, Till-Karsten, E-mail: till-karsten.hauser@med.uni-tuebingen.de [Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076 (Germany)

    2015-06-15

    Highlights: • Reduced FOV imaging enables a 3D approach for a very fast assessment of the orbits. • Conventional MRI exhibited higher eSNR values and consecutively higher scores for overall image quality in the subjective readers’ analysis. • All pathologies could be detected compared to high-resolution conventional MRI making 3D pTX SPACE to a potential alternative and fast imaging technique. - Abstract: Purpose: To prospectively compare the image quality and diagnostic performance of orbital MR images obtained by using a dual-source parallel transmission (pTX) 3D sequence (Sampling Perfection with Application optimized Contrasts using different flip angle Evolution, SPACE) with the image quality of conventional high-resolution standard protocol for clinical use in patients at 3T. Materials and methods: After obtaining institutional review board approval and patient consent, 32 patients with clinical indication for orbital MRI were examined using a high-resolution conventional sequences and 3D pTX SPACE sequences. Quantitative measurements, image quality of the healthy orbit, incidence of artifacts, and the subjective diagnostic performance to establish diagnosis was rated. Statistical significance was calculated by using a Student's t-test and nonparametric Wilcoxon signed rank test. Results: Length measurements were comparable in the two techniques, 3D pTX SPACE resulted in significant faster image acquisition with higher spatial resolution and less motion artifacts as well as better delineation of the optic nerve sheath. However, estimated contrast-to-noise and signal-to-noise and overall image quality as well as subjective scores of the conventional TSE imaging were rated significantly higher. The conventional MR sequences were the preferred techniques by the readers. Conclusion: This study demonstrates the feasibility of 3D pTX SPACE of the orbit resulting in a rapid acquisition of isotropic high-resolution images. Although no pathology was

  7. The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance.

    OpenAIRE

    O'Driscoll, Lorraine

    2016-01-01

    PUBLISHED 2016 Jun 10. doi: 10.18632/oncotarget.9935. [Epub ahead of print] Solid tumours naturally grow in 3D wherein the spatial arrangement of cells affects how they interact with each other. This suggests that 3D cell culture may mimic the natural in vivo setting better than traditional monolayer (2D) cell culture, where cells are grown attached to plastic. Here, using HER2-positive breast cancer cell lines as models (BT474, HCC1954, EFM192A), the effects of culturing c...

  8. 3 D Temperature Field Computation and Thermal Structure Design of Power Inverter for Electric Motor Applications%电机功率逆变器三维温度场计算及散热结构设计

    Institute of Scientific and Technical Information of China (English)

    李争; 邢殿辉; 高培峰

    2015-01-01

    As the core components of electric drive power supply,the power inverter has high power density and more heat production,so it is important to study the thermal safety of power inverter.In this paper, based on the finite volume method,a new electric drive power inverter's thermal performance was analyzed and its thermal structure was analyzed and investigated using 3D temperature field calculation.The designed thermal structure has satisfied heat dissipation performance,which validated by the simulation results.This study provided the basic reference for the integrated design and optimization of the thermal structure of power inverter,and improved the efficiency of design.%功率逆变器作为常用电机驱动电源的核心部件由于其功率密度大、发热量多,对其热安全性的研究显得尤为重要。本文基于有限体积法,对电驱动用功率逆变器进行三维温度场分析,并在此基础上对散热模式和结构进行了分析探讨,所设计结构经仿真分析验证,具有良好的散热性能。在提高设计效率的同时,为功率逆变器散热结构的集成和优化设计提供了借鉴和参考。

  9. Crystal Structure, Thermal Decomposition Behavior and the Standard Molar Enthalpy of Formation of a Novel 3D Hydrogen Bonded Supramolecular [Co(HnicO)2·(H2O)2

    Institute of Scientific and Technical Information of China (English)

    ZENG,Ming-Hua; WU,Mei-Chun; ZHU,Li-Hong; LIANG,Hong; YANG Xu-Wu

    2007-01-01

    Hydrothermal synthesis and X-ray characterized 3D supramolecular networks were constructed by [Co(HnicO)2·(H2O)2] (HnicOH=2-hydroxynicotinic acid) (1) as building block via abundant dimeric homomeric (N-H…O) and unusually cyclic tetrameric heteromeric (O-H…O) hydrogen-bonds. It is noted that there exist unusually linear metal-water chains comprised of tetrameric units linked by vertexes sharing cobalt centers through hydrogen-bonding. TG-DTG curves illustrated that thermal decomposition was completed by two steps, one is the loss of two terminal water molecules in the range of 156-234 ℃, and the other is the pyrolysis of HnicO ligand in the range of 234-730 ℃. The standard molar enthalpy of formation of the complex was determined to be (-1845.43±2.77) kJ·mol-1 by a rotary-bomb combustion calorimeter.

  10. A new bioactive Schiff base ligands derived from propylazo-N-pyrimidin-2-yl-benzenesulfonamides Mn(II) and Cu(II) complexes: Synthesis, thermal and spectroscopic characterization biological studies and 3D modeling structures

    Science.gov (United States)

    Tawfik, Abdelrazak M.; El-ghamry, Mosad A.; Abu-El-Wafa, Samy M.; Ahmed, Naglaa M.

    2012-11-01

    New series of Schiff base ligand H2L and their Cu(II) and Mn(II) complexes derived from azosulfapyrimidine were synthesized and characterized by elemental and thermal studies conductance measurements IR, electronic and EPR spectra. 3D modeling of the ligand indicate that azo group does not participate in complex formation and surface potential on one of the ligand under study indicate that electron density around azomethine groups are much higher than the azo group therefore coordination takes place around azomethine groups. The variety in the geometrical structures depends on the nature of both the metal ions and the Schiff base ligands. The thermo kinetic parameters are calculated and discussed. The biological activities of the ligands and complexes have been screened in vitro against some bacteria and fungi to study their capacity to inhibit their growth and to study the toxicity of the compounds.

  11. Combination of 2D/3D Ligand-Based Similarity Search in Rapid Virtual Screening from Multimillion Compound Repositories. Selection and Biological Evaluation of Potential PDE4 and PDE5 Inhibitors

    Directory of Open Access Journals (Sweden)

    Krisztina Dobi

    2014-05-01

    Full Text Available Rapid in silico selection of target focused libraries from commercial repositories is an attractive and cost effective approach. If structures of active compounds are available rapid 2D similarity search can be performed on multimillion compound databases but the generated library requires further focusing by various 2D/3D chemoinformatics tools. We report here a combination of the 2D approach with a ligand-based 3D method (Screen3D which applies flexible matching to align reference and target compounds in a dynamic manner and thus to assess their structural and conformational similarity. In the first case study we compared the 2D and 3D similarity scores on an existing dataset derived from the biological evaluation of a PDE5 focused library. Based on the obtained similarity metrices a fusion score was proposed. The fusion score was applied to refine the 2D similarity search in a second case study where we aimed at selecting and evaluating a PDE4B focused library. The application of this fused 2D/3D similarity measure led to an increase of the hit rate from 8.5% (1st round, 47% inhibition at 10 µM to 28.5% (2nd round at 50% inhibition at 10 µM and the best two hits had 53 nM inhibitory activities.

  12. Thermal Environment evaluation in Commercial kitchens

    DEFF Research Database (Denmark)

    Simone, Angela; Olesen, Bjarne W.

    2012-01-01

    The indoor climate in commercial kitchens is often unsatisfactory and the working conditions can have a significant effect on employees’ comfort and productivity. The type (fast food, casual, etc.) and climatic zone can influence the thermal conditions in the kitchens. Moreover, size...... and arrangement of the kitchen zones, appliances, etc., complicate further an evaluation of the indoor thermal environment in kitchens. In general, comfort criteria are expressed in international standards such as ASHRAE 55 or ISO EN7730. But are these standardised methods applicable for such environments...... as commercial kitchens? There is therefore a need to study the indoor environment in commercial kitchens and to establish standardized methods and procedures for setting criteria that have to be met for the design and operation of kitchens. The present paper introduces a data collection protocol based...

  13. A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT). Part II: On 3D model accuracy

    NARCIS (Netherlands)

    X. Liang; I. Lambrichts; Y. Sun; K. Denis; B. Hassan; L. Li; R. Pauwels; R. Jacobs

    2010-01-01

    Aim: The study aim was to compare the geometric accuracy of three-dimensional (3D) surface model reconstructions between five Cone Beam Computed Tomography (CBCT) scanners and one Multi-Slice CT (MSCT) system. Materials and methods: A dry human mandible was scanned with five CBCT systems (NewTom 3G,

  14. Evaluation of electric and magnetic fields distribution and SAR induced in 3D models of water containers by radiofrequency radiation using FDTD and FEM simulation techniques

    CERN Document Server

    Abdelsamie, Maher A A; Mustafa, Shuhaimi; Hashim, Dzulkifly

    2014-01-01

    In this study, two software packages using different numerical techniques FEKO 6.3 with Finite-Element Method (FEM) and XFDTD 7 with Finite Difference Time Domain Method (FDTD) were used to assess exposure of 3D models of square, rectangular, and pyramidal shaped water containers to electromagnetic waves at 300, 900, and 2400 MHz frequencies. Using the FEM simulation technique, the peak electric field of 25, 4.5, and 2 V/m at 300 MHz and 15.75, 1.5, and 1.75 V/m at 900 MHz were observed in pyramidal, rectangular, and square shaped 3D container models, respectively. The FDTD simulation method confirmed a peak electric field of 12.782, 10.907, and 10.625 V/m at 2400 MHz in the pyramidal, square, and rectangular shaped 3D models, respectively. The study demonstrated an exceptionally high level of electric field in the water in the two identical pyramid shaped 3D models analyzed using the two different simulation techniques. Both FEM and FDTD simulation techniques indicated variations in the distribution of elect...

  15. Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones

    DEFF Research Database (Denmark)

    Kunick, Conrad; Lauenroth, Kathrin; Wieking, Karen;

    2004-01-01

    With a view to the rational design of selective GSK-3beta inhibitors, 3D-QSAR CoMSIA models were developed for the inhibition of the three serine/threonine kinases CDK1/cyclin B, CDK5/p25, and GSK-3beta by compounds from the paullone inhibitor family. The models are based on the kinase inhibition...

  16. 2D/3D Program work summary report

    International Nuclear Information System (INIS)

    The 2D/3D Program was carried out by Germany, Japan and the United States to investigate the thermal-hydraulics of a PWR large-break LOCA. A contributory approach was utilized in which each country contributed significant effort to the program and all three countries shared the research results. Germany constructed and operated the Upper Plenum Test Facility (UPTF), and Japan constructed and operated the Cylindrical Core Test Facility (CCTF) and the Slab Core Test Facility (SCTF). The US contribution consisted of provision of advanced instrumentation to each of the three test facilities, and assessment of the TRAC computer code against the test results. Evaluations of the test results were carried out in all three countries. This report summarizes the 2D/3D Program in terms of the contributing efforts of the participants, and was prepared in a coordination among three countries. US and Germany have published the report as NUREG/IA-0126 and GRS-100, respectively. (author)

  17. Quantitative evaluation of 3D mouse behaviors and motor function in the open-field after spinal cord injury using markerless motion tracking.

    Directory of Open Access Journals (Sweden)

    Alison L Sheets

    Full Text Available Thousands of scientists strive to identify cellular mechanisms that could lead to breakthroughs in developing ameliorative treatments for debilitating neural and muscular conditions such as spinal cord injury (SCI. Most studies use rodent models to test hypotheses, and these are all limited by the methods available to evaluate animal motor function. This study's goal was to develop a behavioral and locomotor assessment system in a murine model of SCI that enables quantitative kinematic measurements to be made automatically in the open-field by applying markerless motion tracking approaches. Three-dimensional movements of eight naïve, five mild, five moderate, and four severe SCI mice were recorded using 10 cameras (100 Hz. Background subtraction was used in each video frame to identify the animal's silhouette, and the 3D shape at each time was reconstructed using shape-from-silhouette. The reconstructed volume was divided into front and back halves using k-means clustering. The animal's front Center of Volume (CoV height and whole-body CoV speed were calculated and used to automatically classify animal behaviors including directed locomotion, exploratory locomotion, meandering, standing, and rearing. More detailed analyses of CoV height, speed, and lateral deviation during directed locomotion revealed behavioral differences and functional impairments in animals with mild, moderate, and severe SCI when compared with naïve animals. Naïve animals displayed the widest variety of behaviors including rearing and crossing the center of the open-field, the fastest speeds, and tallest rear CoV heights. SCI reduced the range of behaviors, and decreased speed (r = .70 p<.005 and rear CoV height (r = .65 p<.01 were significantly correlated with greater lesion size. This markerless tracking approach is a first step toward fundamentally changing how rodent movement studies are conducted. By providing scientists with sensitive, quantitative

  18. Evaluation of 3D tensor tractography of pyramidal tract depicted by 3T MRI in patients with lacunar infarcts. For prediction of motor function outcome

    International Nuclear Information System (INIS)

    3D tensor tractography (DTT) has been applied to central nervous system (CNS) diseases to depict neuronal fibers. In this study with 3 tesla MRI, we have evaluated DTT to predict outcome of motor function in patients with lacunar infarcts. Fifteen patients with New lacunar infarcts, underwent DTTs with at least one in the acute (mean 1.4 days) and another in the subacute phase (mean 18.7 days). Patients were separated to 2 groups, recovery and non-recovery. Patients in former group had almost complete recovery in motor function 3 month later, while those to latter had a residual hemiparesis. Motor function was assessed with MMT score, which was uniquely stratefied into 12 levels by a modified MMT (manual muscle testing) protocol. DTT was implemented with 3 tesla MRI (Signa Excite; GE) and analyzed with dTV. IISR which was produced by the Department of Radiology, Tokyo University. The pyramidal tract was delineated by setting each region of interest (ROI), with the cerebral peduncle as the seed point and the motor cortex as the target point. The number of pyramidal fibers was identified as drawn lines obtained from a result display. The ratio of the number of fibers (RF) was calculated based on the number of fibers in the injured side relative to the number of fibers in the intact side x 100. In acute phase mean RFs the recovery (70.8±21.6%) and non-recovery (63.5±23.4%) groups were not significantly different. RF of recovery group in subacute phase was 100.5±28.3%, which was significantly higher with that in acute phase, meanwhile there was no significance difference between RFs of non-recovery group in two phases. In addition there was a significant correlation (R2=0.89) between MMT score 3 month later and RF in subacute phase in all patients group. There seems to be a correlation between long-term recovery of motor function and increased numbers in pyramidal fibers defected by DTT. Therefore, DTT may have a potential use in predicting the outcome of patients

  19. Study on the Influence of the Refinement of a 3-D Finite Element Mesh in Springback Evaluation of Plane-Strain Channel Sections

    Science.gov (United States)

    Padmanabhan, R.; Oliveira, M. C.; Baptista, A. J.; Alves, J. L.; Menezes, L. F.

    2007-05-01

    Springback phenomenon associated with the elastic properties of sheet metals makes the design of forming dies a complex task. Thus, to develop consistent algorithms for springback compensation an accurate prediction of the amount of springback is mandatory. The numerical simulation using the finite element method is consensually the only feasible method to predict springback. However, springback prediction is a very complicated task and highly sensitive to various numerical parameters of finite elements (FE), such as: type, order, integration scheme, shape and size, as well the time integration formulae and the unloading strategy. All these numerical parameters make numerical simulation of springback more sensitive to numerical tolerances than the forming operation. In case of an unconstrained cylindrical bending, the in-plane to thickness FE size ratio is more relevant than the number of FE layers through-thickness, for the numerical prediction of final stress and strain states, variables of paramount importance for an accurate springback prediction. The aim of the present work is to evaluate the influence of the refinement of a 3-D FE mesh, namely the in-plane mesh refinement and the number of through-thickness FE layers, in springback prediction. The selected example corresponds to the first stage of the "Numisheet'05 Benchmark♯3", which consists basically in the sheet forming of a channel section in an industrial-scale channel draw die. The physical drawbeads are accurately taken into account in the numerical model in order to accurately reproduce its influence during the forming process simulation. FEM simulations were carried out with the in-house code DD3IMP. Solid finite elements were used. They are recommended for accuracy in FE springback simulation when the ratio between the tool radius and blank thickness is lower than 5-6. In the selected example the drawbead radius is 4.0 mm. The influence of the FE mesh refinement in springback prediction is

  20. LOTT RANCH 3D PROJECT

    International Nuclear Information System (INIS)

    , and scout ticket data were integrated with the 3D interpretations to evaluate drilling opportunities resulting in an initial three well drilling program. Thousands of miles of signed bit data exist. Much of this data was processed during a time when software and hardware capabilities were either incapable or cost prohibitive to glean the full potential of the data. In fact in some circles signed bit gained an undeserved reputation for being less than optimum. As a consequence much of the older signed bit data sits on the shelf long forgotten or overlooked. With the high cost of new acquisition and permitting it might behoove other exploration companies to reconsider resurrecting perfectly viable existing volumes and have them reprocessed at a fraction of the cost of new acquisition

  1. Computation of 3D form factors in complex environments

    International Nuclear Information System (INIS)

    The calculation of radiant interchange among opaque surfaces in a complex environment poses the general problem of determining the visible and hidden parts of the environment. In many thermal engineering applications, surfaces are separated by radiatively non-participating media and may be idealized as diffuse emitters and reflectors. Consenquently the net radiant energy fluxes are intimately related to purely geometrical quantities called form factors, that take into account hidden parts: the problem is reduced to the form factor evaluation. This paper presents the method developed for the computation of 3D form factors in the finite-element module of the system TRIO, which is a general computer code for thermal and fluid flow analysis. The method is derived from an algorithm devised for synthetic image generation. A comparison is performed with the standard contour integration method also implemented and suited to convex geometries. Several illustrative examples of finite-element thermal calculations in radiating enclosures are given

  2. 3D VISUALIZATION FOR VIRTUAL MUSEUM DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    M. Skamantzari

    2016-06-01

    Full Text Available The interest in the development of virtual museums is nowadays rising rapidly. During the last decades there have been numerous efforts concerning the 3D digitization of cultural heritage and the development of virtual museums, digital libraries and serious games. The realistic result has always been the main concern and a real challenge when it comes to 3D modelling of monuments, artifacts and especially sculptures. This paper implements, investigates and evaluates the results of the photogrammetric methods and 3D surveys that were used for the development of a virtual museum. Moreover, the decisions, the actions, the methodology and the main elements that this kind of application should include and take into consideration are described and analysed. It is believed that the outcomes of this application will be useful to researchers who are planning to develop and further improve the attempts made on virtual museums and mass production of 3D models.

  3. Measuring Visual Closeness of 3-D Models

    KAUST Repository

    Morales, Jose A.

    2012-09-01

    Measuring visual closeness of 3-D models is an important issue for different problems and there is still no standardized metric or algorithm to do it. The normal of a surface plays a vital role in the shading of a 3-D object. Motivated by this, we developed two applications to measure visualcloseness, introducing normal difference as a parameter in a weighted metric in Metro’s sampling approach to obtain the maximum and mean distance between 3-D models using 3-D and 6-D correspondence search structures. A visual closeness metric should provide accurate information on what the human observers would perceive as visually close objects. We performed a validation study with a group of people to evaluate the correlation of our metrics with subjective perception. The results were positive since the metrics predicted the subjective rankings more accurately than the Hausdorff distance.

  4. Morphologic Analysis of the Temporomandibular Joint Between Patients With Facial Asymmetry and Asymptomatic Subjects by 2D and 3D Evaluation: A Preliminary Study.

    Science.gov (United States)

    Zhang, Yuan-Li; Song, Jin-Lin; Xu, Xian-Chao; Zheng, Lei-Lei; Wang, Qing-Yuan; Fan, Yu-Bo; Liu, Zhan

    2016-03-01

    Signs and symptoms of temporomandibular joint (TMJ) dysfunction are commonly found in patients with facial asymmetry. Previous studies on the TMJ position have been limited to 2-dimensional (2D) radiographs, computed tomography (CT), or cone-beam computed tomography (CBCT). The purpose of this study was to compare the differences of TMJ position by using 2D CBCT and 3D model measurement methods. In addition, the differences of TMJ positions between patients with facial asymmetry and asymptomatic subjects were investigated. We prospectively recruited 5 patients (cases, mean age, 24.8 ± 2.9 years) diagnosed with facial asymmetry and 5 asymptomatic subjects (controls, mean age, 26 ± 1.2 years). The TMJ spaces, condylar and ramus angles were assessed by using 2D and 3D methods. The 3D models of mandible, maxilla, and teeth were reconstructed with the 3D image software. The variables in each group were assessed by t-test and the level of significance was 0.05. There was a significant difference in the horizontal condylar angle (HCA), coronal condylar angle (CCA), sagittal ramus angle (SRA), medial joint space (MJS), lateral joint space (LJS), superior joint space (SJS), and anterior joint space (AJS) measured in the 2D CBCT and in the 3D models (P < 0.05). The case group had significantly smaller SJS compared to the controls on both nondeviation side (P = 0.009) and deviation side (P = 0.004). In the case group, the nondeviation SRA was significantly larger than the deviation side (P = 0.009). There was no significant difference in the coronal condylar width (CCW) in either group. In addition, the anterior disc displacement (ADD) was more likely to occur on the deviated side in the case group. In conclusion, the 3D measurement method is more accurate and effective for clinicians to investigate the morphology of TMJ than the 2D method. PMID:27043669

  5. 3D-skannaukseen perehtyminen

    OpenAIRE

    Santaluoto, Olli

    2012-01-01

    Tässä insinöörityössä tarkastellaan erilaisia 3D-skannaustekniikoita ja menetelmiä. Työssä myös kerrotaan esimerkkien avulla eri 3D-skannaustekniikoiden käyttökohteista. 3D-skannaus on Suomessa vielä melko harvinaista, siksi eri tekniikat ja käyttömahdollisuudet ovat monille tuntemattomia. 3D-skanneri on laite, jolla tutkitaan reaalimaailman esineitä tai ympäristöä keräämällä dataa kohteen muodoista. 3D-skannerit ovat hyvin paljon vastaavia tavallisen kameran kanssa. Kuten kameroilla, 3D...

  6. 3D Printing Functional Nanocomposites

    OpenAIRE

    Leong, Yew Juan

    2016-01-01

    3D printing presents the ability of rapid prototyping and rapid manufacturing. Techniques such as stereolithography (SLA) and fused deposition molding (FDM) have been developed and utilized since the inception of 3D printing. In such techniques, polymers represent the most commonly used material for 3D printing due to material properties such as thermo plasticity as well as its ability to be polymerized from monomers. Polymer nanocomposites are polymers with nanomaterials composited into the ...

  7. 3D Elevation Program—Virtual USA in 3D

    Science.gov (United States)

    Lukas, Vicki; Stoker, J.M.

    2016-01-01

    The U.S. Geological Survey (USGS) 3D Elevation Program (3DEP) uses a laser system called ‘lidar’ (light detection and ranging) to create a virtual reality map of the Nation that is very accurate. 3D maps have many uses with new uses being discovered all the time.  

  8. 3D IBFV : Hardware-Accelerated 3D Flow Visualization

    NARCIS (Netherlands)

    Telea, Alexandru; Wijk, Jarke J. van

    2003-01-01

    We present a hardware-accelerated method for visualizing 3D flow fields. The method is based on insertion, advection, and decay of dye. To this aim, we extend the texture-based IBFV technique for 2D flow visualization in two main directions. First, we decompose the 3D flow visualization problem in a

  9. Interactive 3D multimedia content

    CERN Document Server

    Cellary, Wojciech

    2012-01-01

    The book describes recent research results in the areas of modelling, creation, management and presentation of interactive 3D multimedia content. The book describes the current state of the art in the field and identifies the most important research and design issues. Consecutive chapters address these issues. These are: database modelling of 3D content, security in 3D environments, describing interactivity of content, searching content, visualization of search results, modelling mixed reality content, and efficient creation of interactive 3D content. Each chapter is illustrated with example a

  10. 3D Bayesian contextual classifiers

    DEFF Research Database (Denmark)

    Larsen, Rasmus

    2000-01-01

    We extend a series of multivariate Bayesian 2-D contextual classifiers to 3-D by specifying a simultaneous Gaussian distribution for the feature vectors as well as a prior distribution of the class variables of a pixel and its 6 nearest 3-D neighbours.......We extend a series of multivariate Bayesian 2-D contextual classifiers to 3-D by specifying a simultaneous Gaussian distribution for the feature vectors as well as a prior distribution of the class variables of a pixel and its 6 nearest 3-D neighbours....

  11. 3-D printers for libraries

    CERN Document Server

    Griffey, Jason

    2014-01-01

    As the maker movement continues to grow and 3-D printers become more affordable, an expanding group of hobbyists is keen to explore this new technology. In the time-honored tradition of introducing new technologies, many libraries are considering purchasing a 3-D printer. Jason Griffey, an early enthusiast of 3-D printing, has researched the marketplace and seen several systems first hand at the Consumer Electronics Show. In this report he introduces readers to the 3-D printing marketplace, covering such topics asHow fused deposition modeling (FDM) printing workBasic terminology such as build

  12. 3D for Graphic Designers

    CERN Document Server

    Connell, Ellery

    2011-01-01

    Helping graphic designers expand their 2D skills into the 3D space The trend in graphic design is towards 3D, with the demand for motion graphics, animation, photorealism, and interactivity rapidly increasing. And with the meteoric rise of iPads, smartphones, and other interactive devices, the design landscape is changing faster than ever.2D digital artists who need a quick and efficient way to join this brave new world will want 3D for Graphic Designers. Readers get hands-on basic training in working in the 3D space, including product design, industrial design and visualization, modeling, ani

  13. Using 3D in Visualization

    DEFF Research Database (Denmark)

    Wood, Jo; Kirschenbauer, Sabine; Döllner, Jürgen;

    2005-01-01

    to display 3D imagery. The extra cartographic degree of freedom offered by using 3D is explored and offered as a motivation for employing 3D in visualization. The use of VR and the construction of virtual environments exploit navigational and behavioral realism, but become most usefil when combined...... with abstracted representations embedded in a 3D space. The interactions between development of geovisualization, the technology used to implement it and the theory surrounding cartographic representation are explored. The dominance of computing technologies, driven particularly by the gaming industry...

  14. Synthesis of 2-substituted methylthieno [2,3- d]pyrimidin-4(3 h-ones and evaluation for antihyperlipidemic activity

    Directory of Open Access Journals (Sweden)

    Murumkar P

    2007-01-01

    Full Text Available A series of nicotinyl 4-oxathieno[2,3- d ]pyridine-2-ylmethyl esters, title compounds were synthesized. Compound IIIa was subjected to in vivo antihyperlipidemic activity in Wistar rats. The activity exhibited by synthesized compound was found to be less as compared to that produced by a standard, atorvastatin, administered in the form of suspension in 2% gum acacia. The activity was even lesser than that produced by the lead IIa.

  15. SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System

    International Nuclear Information System (INIS)

    Purpose: To design, construct and commission a prototype in-house three dimensional (3D) dose verification system for stereotatic body radiotherapy (SBRT) verification at an off-site partner institution. To investigate the potential of this system to achieve sufficient performance (1mm resolution, 3% noise, within 3% of true dose reading) for SBRT verification. Methods: The system was designed utilizing a parallel ray geometry instigated by precision telecentric lenses and an LED 630nm light source. Using a radiochromic dosimeter, a 3D dosimetric comparison with our gold-standard system and treatment planning software (Eclipse) was done for a four-field box treatment, under gamma passing criteria of 3%/3mm/10% dose threshold. Post off-site installation, deviations in the system’s dose readout performance was assessed by rescanning the four-field box irradiated dosimeter and using line-profiles to compare on-site and off-site mean and noise levels in four distinct dose regions. As a final step, an end-to-end test of the system was completed at the off-site location, including CT-simulation, irradiation of the dosimeter and a 3D dosimetric comparison of the planned (Pinnacle3) to delivered dose for a spinal SBRT treatment(12 Gy per fraction). Results: The noise level in the high and medium dose regions of the four field box treatment was relatively 5% pre and post installation. This reflects the reduction in positional uncertainty through the new design. This At 1mm dose voxels, the gamma pass rates(3%,3mm) for our in-house gold standard system and the off-site system were comparable at 95.8% and 93.2% respectively. Conclusion: This work will describe the end-to-end process and results of designing, installing, and commissioning a state-of-the-art 3D dosimetry system created for verification of advanced radiation treatments including spinal radiosurgery

  16. Development of a Hausdorff distance based 3D quantification technique to evaluate the CT imaging system impact on depiction of lesion morphology

    Science.gov (United States)

    Sahbaee, Pooyan; Robins, Marthony; Solomon, Justin; Samei, Ehsan

    2016-04-01

    The purpose of this study was to develop a 3D quantification technique to assess the impact of imaging system on depiction of lesion morphology. Regional Hausdorff Distance (RHD) was computed from two 3D volumes: virtual mesh models of synthetic nodules or "virtual nodules" and CT images of physical nodules or "physical nodules". The method can be described in following steps. First, the synthetic nodule was inserted into anthropomorphic Kyoto thorax phantom and scanned in a Siemens scanner (Flash). Then, nodule was segmented from the image. Second, in order to match the orientation of the nodule, the digital models of the "virtual" and "physical" nodules were both geometrically translated to the origin. Then, the "physical" was gradually rotated at incremental 10 degrees. Third, the Hausdorff Distance was calculated from each pair of "virtual" and "physical" nodules. The minimum HD value represented the most matching pair. Finally, the 3D RHD map and the distribution of RHD were computed for the matched pair. The technique was scalarized using the FWHM of the RHD distribution. The analysis was conducted for various shapes (spherical, lobular, elliptical, and speculated) of nodules. The calculated FWHM values of RHD distribution for the 8-mm spherical, lobular, elliptical, and speculated "virtual" and "physical" nodules were 0.23, 0.42, 0.33, and 0.49, respectively.

  17. 3D-PRINTING OF BUILD OBJECTS

    Directory of Open Access Journals (Sweden)

    SAVYTSKYI M. V.

    2016-03-01

    Full Text Available Raising of problem. Today, in all spheres of our life we can constate the permanent search for new, modern methods and technologies that meet the principles of sustainable development. New approaches need to be, on the one hand more effective in terms of conservation of exhaustible resources of our planet, have minimal impact on the environment and on the other hand to ensure a higher quality of the final product. Construction is not exception. One of the new promising technology is the technology of 3D -printing of individual structures and buildings in general. 3Dprinting - is the process of real object recreating on the model of 3D. Unlike conventional printer which prints information on a sheet of paper, 3D-printer allows you to display three-dimensional information, i.e. creates certain physical objects. Currently, 3D-printer finds its application in many areas of production: machine building elements, a variety of layouts, interior elements, various items. But due to the fact that this technology is fairly new, it requires the creation of detailed and accurate technologies, efficient equipment and materials, and development of common vocabulary and regulatory framework in this field. Research Aim. The analysis of existing methods of creating physical objects using 3D-printing and the improvement of technology and equipment for the printing of buildings and structures. Conclusion. 3D-printers building is a new generation of equipment for the construction of buildings, structures, and structural elements. A variety of building printing technics opens up wide range of opportunities in the construction industry. At this stage, printers design allows to create low-rise buildings of different configurations with different mortars. The scientific novelty of this work is to develop proposals to improve the thermal insulation properties of constructed 3D-printing objects and technological equipment. The list of key terms and notions of construction

  18. Improvement of 3D Scanner

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The disadvantage remaining in 3D scanning system and its reasons are discussed. A new host-and-slave structure with high speed image acquisition and processing system is proposed to quicken the image processing and improve the performance of 3D scanning system.

  19. 3D Printing for Bricks

    OpenAIRE

    ECT Team, Purdue

    2015-01-01

    Building Bytes, by Brian Peters, is a project that uses desktop 3D printers to print bricks for architecture. Instead of using an expensive custom-made printer, it uses a normal standard 3D printer which is available for everyone and makes it more accessible and also easier for fabrication.

  20. 40 CFR 91.427 - Catalyst thermal stress resistance evaluation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Catalyst thermal stress resistance... Procedures § 91.427 Catalyst thermal stress resistance evaluation. (a)(1) The purpose of the evaluation procedure specified in this section is to determine the effect of thermal stress on catalyst...

  1. 3D printing in dentistry.

    Science.gov (United States)

    Dawood, A; Marti Marti, B; Sauret-Jackson, V; Darwood, A

    2015-12-01

    3D printing has been hailed as a disruptive technology which will change manufacturing. Used in aerospace, defence, art and design, 3D printing is becoming a subject of great interest in surgery. The technology has a particular resonance with dentistry, and with advances in 3D imaging and modelling technologies such as cone beam computed tomography and intraoral scanning, and with the relatively long history of the use of CAD CAM technologies in dentistry, it will become of increasing importance. Uses of 3D printing include the production of drill guides for dental implants, the production of physical models for prosthodontics, orthodontics and surgery, the manufacture of dental, craniomaxillofacial and orthopaedic implants, and the fabrication of copings and frameworks for implant and dental restorations. This paper reviews the types of 3D printing technologies available and their various applications in dentistry and in maxillofacial surgery. PMID:26657435

  2. 3D printing in dentistry.

    Science.gov (United States)

    Dawood, A; Marti Marti, B; Sauret-Jackson, V; Darwood, A

    2015-12-01

    3D printing has been hailed as a disruptive technology which will change manufacturing. Used in aerospace, defence, art and design, 3D printing is becoming a subject of great interest in surgery. The technology has a particular resonance with dentistry, and with advances in 3D imaging and modelling technologies such as cone beam computed tomography and intraoral scanning, and with the relatively long history of the use of CAD CAM technologies in dentistry, it will become of increasing importance. Uses of 3D printing include the production of drill guides for dental implants, the production of physical models for prosthodontics, orthodontics and surgery, the manufacture of dental, craniomaxillofacial and orthopaedic implants, and the fabrication of copings and frameworks for implant and dental restorations. This paper reviews the types of 3D printing technologies available and their various applications in dentistry and in maxillofacial surgery.

  3. PLOT3D user's manual

    Science.gov (United States)

    Walatka, Pamela P.; Buning, Pieter G.; Pierce, Larry; Elson, Patricia A.

    1990-01-01

    PLOT3D is a computer graphics program designed to visualize the grids and solutions of computational fluid dynamics. Seventy-four functions are available. Versions are available for many systems. PLOT3D can handle multiple grids with a million or more grid points, and can produce varieties of model renderings, such as wireframe or flat shaded. Output from PLOT3D can be used in animation programs. The first part of this manual is a tutorial that takes the reader, keystroke by keystroke, through a PLOT3D session. The second part of the manual contains reference chapters, including the helpfile, data file formats, advice on changing PLOT3D, and sample command files.

  4. Evaluating 3D printing to solve the sample-to-device interface for LRS and POC diagnostics: example of an interlock meter-mix device for metering and lysing clinical urine samples.

    Science.gov (United States)

    Jue, Erik; Schoepp, Nathan G; Witters, Daan; Ismagilov, Rustem F

    2016-05-21

    This paper evaluates the potential of 3D printing, a semi-automated additive prototyping technology, as a means to design and prototype a sample-to-device interface, amenable to diagnostics in limited-resource settings, where speed, accuracy and user-friendly design are critical components. As a test case, we built and validated an interlock meter-mix device for accurately metering and lysing human urine samples for use in downstream nucleic acid amplification. Two plungers and a multivalve generated and controlled fluid flow through the device and demonstrate the utility of 3D printing to create leak-free seals. Device operation consists of three simple steps that must be performed sequentially, eliminating manual pipetting and vortexing to provide rapid (5 to 10 s) and accurate metering and mixing. Bretherton's prediction was applied, using the bond number to guide a design that prevents potentially biohazardous samples from leaking from the device. We employed multi-material 3D printing technology, which allows composites with rigid and elastomeric properties to be printed as a single part. To validate the meter-mix device with a clinically relevant sample, we used urine spiked with inactivated Chlamydia trachomatis and Neisseria gonorrhoeae. A downstream nucleic acid amplification by quantitative PCR (qPCR) confirmed there was no statistically significant difference between samples metered and mixed using the standard protocol and those prepared with the meter-mix device, showing the 3D-printed device could accurately meter, mix and dispense a human urine sample without loss of nucleic acids. Although there are some limitations to 3D printing capabilities (e.g. dimension limitations related to support material used in the printing process), the advantages of customizability, modularity and rapid prototyping illustrate the utility of 3D printing for developing sample-to-device interfaces for diagnostics. PMID:27122199

  5. Evaluating 3D printing to solve the sample-to-device interface for LRS and POC diagnostics: example of an interlock meter-mix device for metering and lysing clinical urine samples.

    Science.gov (United States)

    Jue, Erik; Schoepp, Nathan G; Witters, Daan; Ismagilov, Rustem F

    2016-05-21

    This paper evaluates the potential of 3D printing, a semi-automated additive prototyping technology, as a means to design and prototype a sample-to-device interface, amenable to diagnostics in limited-resource settings, where speed, accuracy and user-friendly design are critical components. As a test case, we built and validated an interlock meter-mix device for accurately metering and lysing human urine samples for use in downstream nucleic acid amplification. Two plungers and a multivalve generated and controlled fluid flow through the device and demonstrate the utility of 3D printing to create leak-free seals. Device operation consists of three simple steps that must be performed sequentially, eliminating manual pipetting and vortexing to provide rapid (5 to 10 s) and accurate metering and mixing. Bretherton's prediction was applied, using the bond number to guide a design that prevents potentially biohazardous samples from leaking from the device. We employed multi-material 3D printing technology, which allows composites with rigid and elastomeric properties to be printed as a single part. To validate the meter-mix device with a clinically relevant sample, we used urine spiked with inactivated Chlamydia trachomatis and Neisseria gonorrhoeae. A downstream nucleic acid amplification by quantitative PCR (qPCR) confirmed there was no statistically significant difference between samples metered and mixed using the standard protocol and those prepared with the meter-mix device, showing the 3D-printed device could accurately meter, mix and dispense a human urine sample without loss of nucleic acids. Although there are some limitations to 3D printing capabilities (e.g. dimension limitations related to support material used in the printing process), the advantages of customizability, modularity and rapid prototyping illustrate the utility of 3D printing for developing sample-to-device interfaces for diagnostics.

  6. OECD benchmark on thermal fatigue problem - Second step: Evaluation based on FEM

    International Nuclear Information System (INIS)

    In the context of the OECD benchmark on thermal fatigue problem, this report corresponds to the second step of the procedure, i.e. integrity assessment in thermo-mechanical test interpretations. In this second step, participants were asked to estimate the number of cycles to crack initiation on the inner surface, without any initial notch. This report consists of evaluations based on FEM. Thermal and stress calculations are done by 3D-FEM, and based on these results, the number of cycles to crack initiation and propagation are estimated. The main conclusions are the following. Three dimensional Finite Element Analysis with JNC fatigue evaluation procedure estimated the most likely average crack initiation cycle as 2.8 x 104. The maximum Von Mises stress was 708 MPa, and the stress range was 653 MPa. The total strain was 0.48 pc. The estimated cracks are multiple longitudinal ones. Cracking area is from Z=213 to 198 mm and θ is equal to +/- 30 degrees. The cycle number for penetrating the thickness is estimated to be 4.6 x 103 and the crack will reach the outer surface during the planning test period. A detailed estimation of heat transfer coefficients Hwater and Houter is inevitable for a precise stress prediction. Precise estimations of thermal and mechanical properties, especially thermal conductivity, are important for a precise stress prediction. The difference among 3D, 2D, and 1D FEM is large; only 3D FEM can consider global circumstantial temperature difference, which leads to generate large membrane stress. With this membrane stress, the cycle number for crack penetration becomes 9 times shorter than the one without membrane stress. This effect is quite large and the precise estimation of the membrane stress is important

  7. Non-destructive Determination of Residual Stress for the Evaluation of Reliability of 3D-integrated Contact Structures in Silicon

    OpenAIRE

    Zschenderlein, Uwe

    2014-01-01

    Die Arbeit behandelt die zerstörungsfreie Eigenspannungsbestimmung in Silizium von 3D-integrierten Mikrosystemen am Beispiel Wolfram gefüllter TSVs. Dafür wurden die Verfahren der röntgenographischen Spannungsanalyse und der Raman-Spektroskopie genutzt. Interpretiert und verglichen wurden die Ergebnisse mit FE-Simulationen. Als Proben standen Querschliffe eines Doppelchip-Systems zur Verfügung, in denen der obere Chip Wolfram-TSVs enthielt. Beide Chips wurden mit dem Kupfer-Zinn-SLID-Verfahre...

  8. An integrated multidisciplinary re-evaluation of the geothermal system at Valles Caldera, New Mexico, using an immersive three-dimensional (3D) visualization environment

    Science.gov (United States)

    Fowler, A.; Bennett, S. E.; Wildgoose, M.; Cantwell, C.; Elliott, A. J.

    2012-12-01

    We describe an approach to explore the spatial relationships of a geothermal resource by examining diverse geological, geophysical, and geochemical data sets using the immersive 3-dimensional (3D) visualization capabilities of the UC Davis Keck Center for Active Visualization in the Earth Sciences (KeckCAVES). The KeckCAVES is a facility where stereoscopic images are projected onto four, surfaces (three walls and a floor), which the user perceives as a seamless 3D image of the data. The user can manipulate and interact with the data, allowing a more intuitive interpretation of data set relationships than is possible with traditional 2-dimensional techniques. We incorporate multiple data sets of the geothermal system at Valles Caldera, New Mexico: topography, lithology, faults, temperature, alteration mineralogy, and magnetotellurics. With the ability to rapidly and intuitively observe data relationships, we are able to efficiently and rapidly draw conclusions about the subsurface architecture of the Valles Caldera geothermal system. We identify two high-temperature anomalies, one that corresponds with normal faults along the western caldera ring fracture, and one that with the resurgent dome. A cold-temperature anomaly identified adjacent to the resurgent dome high-temperature anomaly appears to relate to a fault controlled graben valley that acts as a recharge zone, likely funneling cold meteoric water into the subsurface along normal faults observed on published maps and cross sections. These high-temperature anomalies broadly correspond to subsurface regions where previous magnetotelluric studies have identified low apparent resistivity. Existing hot springs in the Sulfur Springs area correspond to the only location where our modeled 100°C isotherm intersects the ground surface. Correlation between the first occurrence of key alteration minerals (pyrite, chlorite, epidote) in previously drilled boreholes and our temperature model vary, with chlorite showing a

  9. 3D View of Death Valley, California

    Science.gov (United States)

    2000-01-01

    This 3-D perspective view looking north over Death Valley, California, was produced by draping ASTER nighttime thermal infrared data over topographic data from the US Geological Survey. The ASTER data were acquired April 7, 2000 with the multi-spectral thermal infrared channels, and cover an area of 60 by 80 km (37 by 50 miles). Bands 13, 12, and 10 are displayed in red, green and blue respectively. The data have been computer enhanced to exaggerate the color variations that highlight differences in types of surface materials. Salt deposits on the floor of Death Valley appear in shades of yellow, green, purple, and pink, indicating presence of carbonate, sulfate, and chloride minerals. The Panamint Mtns. to the west, and the Black Mtns. to the east, are made up of sedimentary limestones, sandstones, shales, and metamorphic rocks. The bright red areas are dominated by the mineral quartz, such as is found in sandstones; green areas are limestones. In the lower center part of the image is Badwater, the lowest point in North America.Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of International Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, Calif., is the U.S. Science team leader; Moshe Pniel of JPL is the project manager. ASTER is the only high resolution imaging sensor on Terra. The primary goal of the ASTER mission is to obtain high-resolution image data in 14 channels over the entire land surface, as well as black and white stereo images. With revisit time of between 4 and 16 days, ASTER will provide the capability for repeat coverage of changing areas on Earth's surface.The broad spectral coverage and high spectral resolution of ASTER will provide

  10. Scoops3D: software to analyze 3D slope stability throughout a digital landscape

    Science.gov (United States)

    Reid, Mark E.; Christian, Sarah B.; Brien, Dianne L.; Henderson, Scott T.

    2015-01-01

    The computer program, Scoops3D, evaluates slope stability throughout a digital landscape represented by a digital elevation model (DEM). The program uses a three-dimensional (3D) method of columns approach to assess the stability of many (typically millions) potential landslides within a user-defined size range. For each potential landslide (or failure), Scoops3D assesses the stability of a rotational, spherical slip surface encompassing many DEM cells using a 3D version of either Bishop’s simplified method or the Ordinary (Fellenius) method of limit-equilibrium analysis. Scoops3D has several options for the user to systematically and efficiently search throughout an entire DEM, thereby incorporating the effects of complex surface topography. In a thorough search, each DEM cell is included in multiple potential failures, and Scoops3D records the lowest stability (factor of safety) for each DEM cell, as well as the size (volume or area) associated with each of these potential landslides. It also determines the least-stable potential failure for the entire DEM. The user has a variety of options for building a 3D domain, including layers or full 3D distributions of strength and pore-water pressures, simplistic earthquake loading, and unsaturated suction conditions. Results from Scoops3D can be readily incorporated into a geographic information system (GIS) or other visualization software. This manual includes information on the theoretical basis for the slope-stability analysis, requirements for constructing and searching a 3D domain, a detailed operational guide (including step-by-step instructions for using the graphical user interface [GUI] software, Scoops3D-i) and input/output file specifications, practical considerations for conducting an analysis, results of verification tests, and multiple examples illustrating the capabilities of Scoops3D. Easy-to-use software installation packages are available for the Windows or Macintosh operating systems; these packages

  11. Spectroradiometric characterization of autostereoscopic 3D displays

    Science.gov (United States)

    Rubiño, Manuel; Salas, Carlos; Pozo, Antonio M.; Castro, J. J.; Pérez-Ocón, Francisco

    2013-11-01

    Spectroradiometric measurements have been made for the experimental characterization of the RGB channels of autostereoscopic 3D displays, giving results for different measurement angles with respect to the normal direction of the plane of the display. In the study, 2 different models of autostereoscopic 3D displays of different sizes and resolutions were used, making measurements with a spectroradiometer (model PR-670 SpectraScan of PhotoResearch). From the measurements made, goniometric results were recorded for luminance contrast, and the fundamental hypotheses have been evaluated for the characterization of the displays: independence of the RGB channels and their constancy. The results show that the display with the lower angle variability in the contrast-ratio value and constancy of the chromaticity coordinates nevertheless presented the greatest additivity deviations with the measurement angle. For both displays, when the parameters evaluated were taken into account, lower angle variability consistently resulted in the 2D mode than in the 3D mode.

  12. 3-D Video Processing for 3-D TV

    Science.gov (United States)

    Sohn, Kwanghoon; Kim, Hansung; Kim, Yongtae

    One of the most desirable ways of realizing high quality information and telecommunication services has been called "The Sensation of Reality," which can be achieved by visual communication based on 3-D (Three-dimensional) images. These kinds of 3-D imaging systems have revealed potential applications in the fields of education, entertainment, medical surgery, video conferencing, etc. Especially, three-dimensional television (3-D TV) is believed to be the next generation of TV technology. Figure 13.1 shows how TV's display technologies have evolved , and Fig. 13.2 details the evolution of TV broadcasting as forecasted by the ETRI (Electronics and Telecommunications Research Institute). It is clear that 3-D TV broadcasting will be the next development in this field, and realistic broadcasting will soon follow.

  13. 3D-OCT对早期原发性青光眼黄斑区视网膜神经节细胞复合体及神经纤维层结构变化的评估%Evaluation of macular ganglion cell complex and peripheral retinal nerve fiber layer structural damage in early primary glaucomous eyes by 3D-OCT

    Institute of Scientific and Technical Information of China (English)

    严钰洁; 孙心铨; 陈术; 施爱群; 王志军

    2016-01-01

    常或轻微变薄.结论 原发性青光眼mGCC层厚度变薄早于视盘周围RNFL的变薄,提示青光眼视神经结构的损害始于RGCs的细胞体并早于轴突的损伤或丢失.%Background In previous study,peripheral retinal nerve fiber layer (RNFL) thickness is considered to be the earliest structural changes which can be detected.3D-OCT can measure the thickness of macular ganglion cell complex (mGCC),which makes the detection of primary glaucoma possible in the early stage.Objective This study was to measure the thickness of mGCC and disc-peripheral RNFL in early stage of primary glaucomous eyes by 3D-OCT and assess the anatomic basis of glaucoma-induced optical nerve damage.Methods 3D-OCT images from 10 patients with advanced stage primary glaucoma in one lateral eye and early stage glaucoma in fellow eye from December 2010 to December 2012 were prospectively analyzed in China-Japan Friendship Hospital.The patients were diagnosed based on the recommended standard of National glaucoma group (1987 version) and received routine eye examination.3D-OCT scanning was performed using 3D-macular mode,3D-macular Wide mode and 3D-disc mode with TOPCON 3D-OCT 2000 system,and the images at macular 6 mm×6 mm area were analyzed.The posterior pole area was divided into 5 concentric rings from fovea toward periphery and equally subdivided into 100 small checks,with the area of 0.6 mm×0.6 mm for each.The probable values in each check were calculated as the ratio of each figure and corresponding normal value.The probable values were expressed as red color (P< 1%),yellow color (P<5%) and gray color (P≥ 5%).Then the disc-periphery RNFL thickness and disc cup were evaluated.Results No evident abnormality was found in the thicknesses of photoreceptors layer and bipolar cell layer in both advanced glaucomous eyes and the early stage of glaucomous eyes in the 10 patients.Serious damage of visual field was seen in the advanced glaucomous eyes and presented with red color in the

  14. ADT-3D Tumor Detection Assistant in 3D

    Directory of Open Access Journals (Sweden)

    Jaime Lazcano Bello

    2008-12-01

    Full Text Available The present document describes ADT-3D (Three-Dimensional Tumor Detector Assistant, a prototype application developed to assist doctors diagnose, detect and locate tumors in the brain by using CT scan. The reader may find on this document an introduction to tumor detection; ADT-3D main goals; development details; description of the product; motivation for its development; result’s study; and areas of applicability.

  15. Development and evaluation of a new 3-D digitization and computer graphic system to study the anatomic tissue and restoration surfaces.

    Science.gov (United States)

    Dastane, A; Vaidyanathan, T K; Vaidyanathan, J; Mehra, R; Hesby, R

    1996-01-01

    It is necessary to visualize and reconstruct tissue anatomic surfaces accurately for a variety of oral rehabilitation applications such as surface wear characterization and automated fabrication of dental restorations, accuracy of reproduction of impression and die materials, etc. In this investigation, a 3-D digitization and computer-graphic system was developed for surface characterization. The hardware consists of a profiler assembly for digitization in an MTS biomechanical test system with an artificial mouth, an IBM PS/2 computer model 70 for data processing and a Hewlett-Packard laser printer for hardcopy outputs. The software used includes a commercially available Surfer 3-D graphics package, a public domain data-fitting alignment software and an inhouse Pascal program for intercommunication plus some other limited tasks. Surfaces were digitized before and after rotation by angular displacement, the digital data were interpolated by Surfer to provide a data grid and the surfaces were computer graphically reconstructed: Misaligned surfaces were aligned by the data-fitting alignment software under different choices of parameters. The effect of different interpolation parameters (e.g. grid size, method of interpolation) and extent of rotation on the alignment accuracy was determined. The results indicate that improved alignment accuracy results from optimization of interpolation parameters and minimization of the initial misorientation between the digitized surfaces. The method provides important advantages for surface reconstruction and visualization, such as overlay of sequentially generated surfaces and accurate alignment of pairs of surfaces with small misalignment.

  16. Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of TS and AICARFTase and as potential antitumor agents.

    Science.gov (United States)

    Liu, Yi; Li, Meng; Zhang, Hongying; Yuan, Jiangsong; Zhang, Congying; Zhang, Kai; Guo, Huicai; Zhao, Lijuan; Du, Yumin; Wang, Lei; Ren, Leiming

    2016-06-10

    A new series of 2-amino-4-oxo-6-substituted pyrrolo[2,3-d]pyrimidines, with an isosteric replacement of the side chain amide moiety to a sulfur atom, were designed and synthesized as multitargeted antifolates as well as potential antitumor agents. Starting from previously synthesized 2-amino-4-oxo-pyrrolo[2,3-d]pyrimidin-6-yl-acetic acid, a reduction by lithium triethylborohydride and successive mesylation afforded the key mesylate. Nucleophilic substitution by mercaptoacetic or mercaptopropionic acid methyl esters, followed by hydrolysis and condensation with pyridinyl-methylamines provided the nonclassical compounds 1-6, whereas condensation with glutamic acid diethyl ester hydrochloride and saponification afforded the classical analogs 7-8. All target compounds exhibited inhibitory activities toward KB, SW620 and A549 tumor cell lines. The most potent compounds of this series, 7 and 8, are better inhibitors against A549 cells than methotrexate (MTX) and pemetrexed (PMX). Nucleoside protection assays establish compound 8 a dual inhibitor of thymidylate synthase (TS) and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFTase) targeting both de novo thymidylate and purine nucleotide biosynthesis, which is further verified by the molecular modeling studies. Analogous to PMX, target compound 8 alternates the cell cycle of SW620 cells with S-phase accumulation and induces apoptosis, leading to cell death. PMID:27017552

  17. Handbook of 3D integration

    CERN Document Server

    Garrou , Philip; Ramm , Peter

    2014-01-01

    Edited by key figures in 3D integration and written by top authors from high-tech companies and renowned research institutions, this book covers the intricate details of 3D process technology.As such, the main focus is on silicon via formation, bonding and debonding, thinning, via reveal and backside processing, both from a technological and a materials science perspective. The last part of the book is concerned with assessing and enhancing the reliability of the 3D integrated devices, which is a prerequisite for the large-scale implementation of this emerging technology. Invaluable reading fo

  18. Tuotekehitysprojekti: 3D-tulostin

    OpenAIRE

    Pihlajamäki, Janne

    2011-01-01

    Opinnäytetyössä tutustuttiin 3D-tulostamisen teknologiaan. Työssä käytiin läpi 3D-tulostimesta tehty tuotekehitysprojekti. Sen lisäksi esiteltiin yleisellä tasolla tuotekehitysprosessi ja syntyneiden tulosten mahdollisia suojausmenetelmiä. Tavoitteena tässä työssä oli kehittää markkinoilta jo löytyvää kotitulostin-tasoista 3D-laiteteknologiaa lähemmäksi ammattilaistason ratkaisua. Tavoitteeseen pyrittiin keskittymällä parantamaan laitteella saavutettavaa tulostustarkkuutta ja -nopeutt...

  19. 3D on the internet

    OpenAIRE

    Puntar, Matej

    2012-01-01

    The purpose of this thesis is the presentation of already established and new technologies of displaying 3D content in a web browser. The thesis begins with a short presentation of the history of 3D content available on the internet and its development together with advantages and disadvantages of individual technologies. The latter two are described in detail as well is their use and the differences among them. Special emphasis has been given to WebGL, the newest technology of 3D conte...

  20. Color 3D Reverse Engineering

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper presents a principle and a method of col or 3D laser scanning measurement. Based on the fundamental monochrome 3D measureme nt study, color information capture, color texture mapping, coordinate computati on and other techniques are performed to achieve color 3D measurement. The syste m is designed and composed of a line laser light emitter, one color CCD camera, a motor-driven rotary filter, a circuit card and a computer. Two steps in captu ring object's images in the measurement process: Firs...

  1. Exploration of 3D Printing

    OpenAIRE

    Lin, Zeyu

    2014-01-01

    3D printing technology is introduced and defined in this Thesis. Some methods of 3D printing are illustrated and their principles are explained with pictures. Most of the essential parts are presented with pictures and their effects are explained within the whole system. Problems on Up! Plus 3D printer are solved and a DIY product is made with this machine. The processes of making product are recorded and the items which need to be noticed during the process are the highlight in this th...

  2. 计入三维热效应对可倾瓦推力轴承动力特性的影响%Influence of Considering 3D Thermal Effects on Dynamic Characteristics of Tilting Pad Thrust Bearing

    Institute of Scientific and Technical Information of China (English)

    何加猛; 王小静; 祁高安; 黄敏

    2012-01-01

    在考虑三维热效应的情况下,研究线支撑可倾瓦推力轴承的动力特性.建立广义雷诺方程、完整的三维能量方程、瓦体的热传导方程和温粘关系,联立求解非线性偏微分方程组,计算油膜的刚度和阻尼系数.研究表明:温度变化对可倾瓦推力轴承的动力特性有较大影响;与不计入热效应的线支撑可倾瓦推力轴承相比,计入三维热流体的可倾瓦推力轴承的油膜刚度和阻尼系数会增大,其理论计算结果更接近实际工况;随着载荷、入口温度的增加以及转速的减小,油膜的刚度和阻尼也会随之增大.%The dynamic characteristics of the line-supported tilting pad thrust bearing are studied by taking thermal effects into account. The generalized Reynolds equation, the complete 3D energy equation, the heat conduction equation of the pad, and the temperature viscosity relation are established to derive the stiffness and damping coefficient of the oil film on the tilting pad. It is shown that the thermal effects have significant influence on the dynamic characteristics of tilting thrust pads. Compared to the line-supported tilting pad without including the thermal effect, stiffness and damping coefficient of the oil film including the thermal effect increases so that it becomes closer to the actual operating conditions. With the increase of load and inlet temperature and the decrease of angular velocity, stiffness and the damping coefficient of the oil film will increase.

  3. 视频立体增强现实系统舒适度评价方法研究%Study on Video 3D AR Systems Comfort Evaluation Method

    Institute of Scientific and Technical Information of China (English)

    李壮恒; 王涌天; 翁冬冬

    2012-01-01

    The evaluation of the effectiveness of stereo images ss a hot issue. Many researchers made intensive studies of this. However, few researches are focused on the 3D effects of 3D augmented reality system. In this paper we studied on Comfort Level Evaluation in see - through 3D augmented reality systems. We designed three experiments for the analysis the factors that impact the comfort level of see - through 3D augmented reality systems. The experiments show that the matching of virtual camera and real camera parameters affects the comfort level. This paper has a certain reference value for 3D augmented reality system design.%立体图像效果的评价是一个热点问题,许多文献对此进行了深入的探讨.但是,对于立体增强现实系统的立体效果进行研究的文献比较少,针对视频透射式立体增强现实系统,对