WorldWideScience

Sample records for 2d pattern evolution

  1. From 2D Lithography to 3D Patterning

    NARCIS (Netherlands)

    Van Zeijl, H.W.; Wei, J.; Shen, C.; Verhaar, T.M.; Sarro, P.M.

    2010-01-01

    Lithography as developed for IC device fabrication is a high volume high accuracy patterning technology with strong 2 dimensional (2D) characteristics. This 2D nature makes it a challenge to integrate this technology in a 3 dimensional (3D) manufacturing environment. This article addresses the perfo

  2. Dynamic and approximate pattern matching in 2D

    DEFF Research Database (Denmark)

    Clifford, Raphaël; Fontaine, Allyx; Starikovskaya, Tatiana

    2016-01-01

    updates can be performed in O(log2 n) time and queries in O(log2 m) time. - We then consider a model where an update is a new 2D pattern and a query is a location in the text. For this setting we show that Hamming distance queries can be answered in O(log m + H) time, where H is the relevant Hamming...... distance. - Extending this work to allow approximation, we give an efficient algorithm which returns a (1+ε) approximation of the Hamming distance at a given location in O(ε−2 log2 m log log n) time. Finally, we consider a different setting inspired by previous work on locality sensitive hashing (LSH......). Given a threshold k and after building the 2D text index and receiving a 2D query pattern, we must output a location where the Hamming distance is at most (1 + ε)k as long as there exists a location where the Hamming distance is at most k. - For our LSH inspired 2D indexing problem, the text can...

  3. Planar maps, circle patterns and 2d gravity

    CERN Document Server

    David, Francois

    2013-01-01

    Via circle pattern techniques, random planar triangulations (with angle variables) are mapped onto Delaunay triangulations in the complex plane. The uniform measure on triangulations is mapped onto a conformally invariant spatial point process. We show that this measure can be expressed as: (1) a sum over 3-spanning-trees partitions of the edges of the Delaunay triangulations; (2) the volume form of a K\\"ahler metric over the space of Delaunay triangulations, whose prepotential has a simple formulation in term of ideal tessellations of the 3d hyperbolic space; (3) a discretized version (involving finite difference complex derivative operators) of Polyakov's conformal Fadeev-Popov determinant in 2d gravity; (4) a combination of Chern classes, thus also establishing a link with topological 2d gravity.

  4. Galaxy distribution and evolution around a sample of 2dF groups

    CERN Document Server

    Ribeiro, A L B; Lopes, P A A; Schilling, A C

    2009-01-01

    We study galaxy evolution and spatial patterns in the surroundings of a sample of 2dF groups. Our aim is to find evidence of galaxy evolution and clustering out to 10 times the virial radius of the groups and so redefine their properties according to the spatial patterns in the fields and relate them to galaxy evolution. Group members and interlopers were redefined after the identification of gaps in the redshift distribution. We then used exploratory spatial statistics based on the second moment of the Ripley function to probe the anisotropy in the galaxy distribution around the groups. We found an important anticorrelation between anisotropy and the fraction of early-type galaxies in these fields. Our results illustrate how the dynamical state of galaxy groups can be determined through the systematic study of their neighborhoods.

  5. Evolution of Matter Wave Interference of Bose-Condensed Gas in a 2D Optical Lattice

    Institute of Scientific and Technical Information of China (English)

    XUZhi-Jun; LINGuo-Cheng; XUJun; LIZhen

    2005-01-01

    We investigate the average particle-number distribution of the atoms in the combined potential of 2D optical lattices and 31) harmonic magnetic trap based on the Gross-Pitaevskii equation. After the combined potential is switched of[, and only the optical lattice is switched off, we give the analytical results of the wavefunction of the Bosecondensed gas at any time t by using a propagator method. For both disk-shaped and cigar-shaped Bose-condensed gas,we discuss the evolution process of the central and side peaks of the interference pattern.

  6. Galaxy distribution and evolution around a sample of 2dF groups

    Science.gov (United States)

    Ribeiro, A. L. B.; Trevisan, M.; Lopes, P. A. A.; Schilling, A. C.

    2009-10-01

    Context: We study galaxy evolution and spatial patterns in the surroundings of a sample of 2dF groups. Aims: Our aim is to find evidence of galaxy evolution and clustering out to 10 times the virial radius of the groups and so redefine their properties according to the spatial patterns in the fields and relate them to galaxy evolution. Methods: Group members and interlopers were redefined after the identification of gaps in the redshift distribution. We then used exploratory spatial statistics based on the the second moment of the Ripley function to probe the anisotropy in the galaxy distribution around the groups. Results: We found an important anticorrelation between anisotropy around groups and the fraction of early-type galaxies in these fields. Our results illustrate how the dynamical state of galaxy groups can be ascertained by the systematic study of their neighborhoods. This is an important achievement, since the correct estimate of the extent to which galaxies are affected by the group environment and follow large-scale filamentary structure is relevant to understanding the process of galaxy clustering and evolution in the Universe.

  7. 2-D traveling-wave patterns in binary fluid convection

    Energy Technology Data Exchange (ETDEWEB)

    Surko, C.M.; Porta, A.L. [Univ. of California, La Jolla, CA (United States)

    1996-12-31

    An overview is presented of recent experiments designed to study two-dimensional traveling-wave convection in binary fluid convection in a large aspect ratio container. Disordered patterns are observed when convection is initiated. As time proceeds, they evolve to more ordered patterns, consisting of several domains of traveling-waves separated by well-defined domain boundaries. The detailed character of the patterns depends sensitively on the Rayleigh number. Numerical techniques are described which were developed to provide a quantitative characterization of the traveling-wave patterns. Applications of complex demodulation techniques are also described, which make a detailed study of the structure and dynamics of the domain boundaries possible.

  8. Short local descriptors from 2D connected pattern spectra

    NARCIS (Netherlands)

    Bosilj, Petra; Kijak, Ewa; Wilkinson, Michael H. F.; Lefèvre, Sebastien

    2015-01-01

    We propose a local region descriptor based on connected pattern spectra, and combined with normalized central moments. The descriptors are calculated for MSER regions of the image, and their performance compared against SIFT. The MSER regions were chosen because they can be efficiently selected by c

  9. Groupware requirements evolution patterns

    NARCIS (Netherlands)

    Pumareja, Dulce Trinidad

    2013-01-01

    Requirements evolution is a generally known problem in software development. Requirements are known to change all throughout a system's lifecycle. Nevertheless, requirements evolution is a poorly understood phenomenon. Most studies on requirements evolution focus on changes to written specifications

  10. Differential patterns of 2D location versus depth decoding along the visual hierarchy.

    Science.gov (United States)

    Finlayson, Nonie J; Zhang, Xiaoli; Golomb, Julie D

    2017-02-15

    Visual information is initially represented as 2D images on the retina, but our brains are able to transform this input to perceive our rich 3D environment. While many studies have explored 2D spatial representations or depth perception in isolation, it remains unknown if or how these processes interact in human visual cortex. Here we used functional MRI and multi-voxel pattern analysis to investigate the relationship between 2D location and position-in-depth information. We stimulated different 3D locations in a blocked design: each location was defined by horizontal, vertical, and depth position. Participants remained fixated at the center of the screen while passively viewing the peripheral stimuli with red/green anaglyph glasses. Our results revealed a widespread, systematic transition throughout visual cortex. As expected, 2D location information (horizontal and vertical) could be strongly decoded in early visual areas, with reduced decoding higher along the visual hierarchy, consistent with known changes in receptive field sizes. Critically, we found that the decoding of position-in-depth information tracked inversely with the 2D location pattern, with the magnitude of depth decoding gradually increasing from intermediate to higher visual and category regions. Representations of 2D location information became increasingly location-tolerant in later areas, where depth information was also tolerant to changes in 2D location. We propose that spatial representations gradually transition from 2D-dominant to balanced 3D (2D and depth) along the visual hierarchy.

  11. Theoretical study of acoustic field patterns of 2-D ultrasound phased arrays for hyperthermia therapy

    Institute of Scientific and Technical Information of China (English)

    HUO Jian; ZHANG Wei; SHI Keren

    2005-01-01

    Acoustic field patterns of 2-D ultrasound phased arrays for the high intensity focused ultrasound (HIFU) hyperthermia therapy are studied, and controlling algorithms of field patterns are provided. The 2-D phased array using the conventional single-focus scanning pattern can exactly control the focal distance and the steering direction of the beam, but in general produce a single focus. Extremely high intensity levels will be needed when this pattern is used to treat large tumors. However, a direct synthesis method of the acoustic field based on the pseudo-inverse matrix can produce the multiple-focus field pattern. The rectangular radiator method of the acoustic field was used to simulate the single-focus scanning pattern and the multiple-focus pattern which are produced by a 2-D phased array consisting of 20×20 elements,and simulation results show that the 2-D array using the multiple-focus pattern can produce several foci with lower intensity levels simultaneously. Furthermore, the improved eigenvector algorithm was used to optimize the intensity gain of the multiple-focus pattern. It is shown to increase the power deposition in the target volume and eliminate the undesired interference.And the multiple-focus pattern also allows the complex excitation vector to be weighted to increase the array excitation efficiency, and therefore we can only control the phase distribution of the excitation vector to realize the phase-only multiple-focus pattern synthesis.

  12. Fast Computation of Wideband Beam Pattern for Designing Large-Scale 2-D Arrays.

    Science.gov (United States)

    Chi, Cheng; Li, Zhaohui

    2016-06-01

    For real-time and high-resolution 3-D ultrasound imaging, the design of sparse distribution and weights of elements of a large-scale wideband 2-D array is needed to reduce hardware cost and achieve better directivity. However, due to the high time consumption of computing the wideband beam pattern, the design methods that need massive iterations have rarely been applied to design large-scale wideband 2-D arrays by directly computing the wideband beam pattern. In this paper, a fast method is proposed to realize the computation of a wideband beam pattern of arbitrary 2-D arrays in the far field in order to design large-scale wideband 2-D arrays. The proposed fast method exploits two important techniques: 1) nonuniform fast Fourier transform (FFT) and 2) short inverse FFT. Compared with the commonly used ultrasound simulator Field II, two orders of magnitude improvement in computation speed is achieved with comparable accuracy. The proposed fast method enables massive iterations of direct wideband beam pattern computation of arbitrary large-scale 2-D arrays. A design example in this paper demonstrates that the proposed fast method can help achieve better performance in designing large-scale wideband 2-D arrays.

  13. EVOLUTION OF A 2-D DISTURBANCE IN A SUPERSONIC BOUNDARY LAYER AND THE GENERATION OF SHOCKLETS

    Institute of Scientific and Technical Information of China (English)

    黄章峰; 周恒

    2004-01-01

    Through direct numerical simulation, the evolution of a 2-D disturbance in a supersonic boundary layer has been investigated. At a chosen location, a small amplitude T-S wave was fed into the boundary layer to investigate its evolution. Characteristics of nonlinear evolution have been found. Two methods were applied for the detection of shocklets ,and it was found that when the amplitude of the disturbance reached a certain value,shocklets would be generated, which should be taken into consideration when nonlinear theory of hydrodynamic stability for compressible flows is to be established.

  14. 2D pattern evolution constrained by complex network dynamics

    CERN Document Server

    Rocha, L E C; Costa, Luciano da Fontoura; Rocha, Luis Enrique Correa da

    2006-01-01

    Complex networks have established themselves along the last years as being particularly suitable and flexible for representing and modeling several complex natural and human-made systems. At the same time in which the structural intricacies of such networks are being revealed and understood, efforts have also been directed at investigating how such connectivity properties define and constrain the dynamics of systems unfolding on such structures. However, lesser attention has been focused on hybrid systems, \\textit{i.e.} involving more than one type of network and/or dynamics. Because several real systems present such an organization (\\textit{e.g.} the dynamics of a disease coexisting with the dynamics of the immune system), it becomes important to address such hybrid systems. The current paper investigates a specific system involving a diffusive (linear and non-linear) dynamics taking place in a regular network while interacting with a complex network of defensive agents following Erd\\"os-R\\'enyi and Barab\\'a...

  15. Stochastic 2-D Models of Galaxy Disk Evolution. The Galaxy M33

    CERN Document Server

    Mineikis, Tadas

    2015-01-01

    We have developed a fast numerical 2-D model of galaxy disk evolution (resolved along the galaxy radius and azimuth) by adopting a scheme of parameterized stochastic self-propagating star formation. We explore the parameter space of the model and demonstrate its capability to reproduce 1-D radial profiles of the galaxy M33: gas surface density, surface brightness in the i and GALEX FUV passbands, and metallicity.

  16. Prolegomenon to patterns in evolution.

    Science.gov (United States)

    Kauffman, Stuart A

    2014-09-01

    Despite Darwin, we remain children of Newton and dream of a grand theory that is epistemologically complete and would allow prediction of the evolution of the biosphere. The main purpose of this article is to show that this dream is false, and bears on studying patterns of evolution. To do so, I must justify the use of the word "function" in biology, when physics has only happenings. The concept of "function" lifts biology irreducibly above physics, for as we shall see, we cannot prestate the ever new biological functions that arise and constitute the very phase space of evolution. Hence, we cannot mathematize the detailed becoming of the biosphere, nor write differential equations for functional variables we do not know ahead of time, nor integrate those equations, so no laws "entail" evolution. The dream of a grand theory fails. In place of entailing laws, I propose a post-entailing law explanatory framework in which Actuals arise in evolution that constitute new boundary conditions that are enabling constraints that create new, typically unprestatable, adjacent possible opportunities for further evolution, in which new Actuals arise, in a persistent becoming. Evolution flows into a typically unprestatable succession of adjacent possibles. Given the concept of function, the concept of functional closure of an organism making a living in its world becomes central. Implications for patterns in evolution include historical reconstruction, and statistical laws such as the distribution of extinction events, or species per genus, and the use of formal cause, not efficient cause, laws.

  17. Removal of Spectro-Polarimetric Fringes by 2D Pattern Recognition

    OpenAIRE

    Casini, R.; Judge, P. G.; Schad, T. A.

    2012-01-01

    We present a pattern-recognition based approach to the problem of removal of polarized fringes from spectro-polarimetric data. We demonstrate that 2D Principal Component Analysis can be trained on a given spectro-polarimetric map in order to identify and isolate fringe structures from the spectra. This allows us in principle to reconstruct the data without the fringe component, providing an effective and clean solution to the problem. The results presented in this paper point in the direction...

  18. Film flows and self-organized patterns of 2D-localized structures

    Energy Technology Data Exchange (ETDEWEB)

    Frenkel, A.L. [Univ. of Alabama, Tuscaloosa, AL (United States)

    1996-12-31

    Films flowing down an inclined plane are considered. An unconventional perturbation approach is discussed. It yields the most general evolution equation for film thickness and the least restrictive conditions for its validity. Results of numerical simulations of the dissipative-dispersive evolution equation indicate that novel, more complex type of spatiotemporal patterns can exist for strange attractors of nonequilibrium systems. It is suggested that real-life experiments satisfying the validity conditions of this theory are possible.

  19. 2D cellular automaton model for the evolution of active region coronal plasmas

    CERN Document Server

    Fuentes, Marcelo López

    2016-01-01

    We study a 2D cellular automaton (CA) model for the evolution of coronal loop plasmas. The model is based on the idea that coronal loops are made of elementary magnetic strands that are tangled and stressed by the displacement of their footpoints by photospheric motions. The magnetic stress accumulated between neighbor strands is released in sudden reconnection events or nanoflares that heat the plasma. We combine the CA model with the Enthalpy Based Thermal Evolution of Loops (EBTEL) model to compute the response of the plasma to the heating events. Using the known response of the XRT telescope on board Hinode we also obtain synthetic data. The model obeys easy to understand scaling laws relating the output (nanoflare energy, temperature, density, intensity) to the input parameters (field strength, strand length, critical misalignment angle). The nanoflares have a power-law distribution with a universal slope of -2.5, independent of the input parameters. The repetition frequency of nanoflares, expressed in t...

  20. Pruned Continuous Haar Transform of 2D Polygonal Patterns with Application to VLSI Layouts

    CERN Document Server

    Scheibler, Robin; Chebira, Amina

    2011-01-01

    We introduce an algorithm for the efficient computation of the continuous Haar transform of 2D patterns that can be described by polygons. These patterns are ubiquitous in VLSI processes where they are used to describe design and mask layouts. There, speed is of paramount importance due to the magnitude of the problems to be solved and hence very fast algorithms are needed. We show that by techniques borrowed from computational geometry we are not only able to compute the continuous Haar transform directly, but also to do it quickly. This is achieved by massively pruning the transform tree and thus dramatically decreasing the computational load when the number of vertices is small, as is the case for VLSI layouts. We call this new algorithm the pruned continuous Haar transform. We implement this algorithm and show that for patterns found in VLSI layouts the proposed algorithm was in the worst case as fast as its discrete counterpart and up to 12 times faster.

  1. Removal of Spectro-Polarimetric Fringes by 2D Pattern Recognition

    CERN Document Server

    Casini, R; Schad, T A

    2012-01-01

    We present a pattern-recognition based approach to the problem of removal of polarized fringes from spectro-polarimetric data. We demonstrate that 2D Principal Component Analysis can be trained on a given spectro-polarimetric map in order to identify and isolate fringe structures from the spectra. This allows us in principle to reconstruct the data without the fringe component, providing an effective and clean solution to the problem. The results presented in this paper point in the direction of revising the way that science and calibration data should be planned for a typical spectro-polarimetric observing run.

  2. Patterned Peeling 2D MoS2 off the Substrate.

    Science.gov (United States)

    Zhao, Jing; Yu, Hua; Chen, Wei; Yang, Rong; Zhu, Jianqi; Liao, Mengzhou; Shi, Dongxia; Zhang, Guangyu

    2016-07-01

    The performance of two-dimensional (2D) MoS2 devices depends largely on the quality of the MoS2 itself. Existing fabrication process for 2D MoS2 relies on lithography and etching. However, it is extremely difficult to achieve clean patterns without any contaminations or passivations. Here we report a peel-off pattering of MoS2 films on substrates based on a proper interface engineering. The peel-off process utilizes the strong adhesion between gold and MoS2 and removes the MoS2 film contact with gold directly, leading to clean MoS2 pattern generation without residuals. Significantly improved electrical performances including high mobility ∼17.1 ± 8.3 cm(2)/(V s) and on/off ratio ∼5.6 ± 3.6 × 10(6) were achieved. Such clean fabrication technique paves a way to high quality MoS2 devices for various electrical and optical applications.

  3. 2D-patterning of self-assembled silver nanoisland films.

    Science.gov (United States)

    Chervinskii, Semen; Reduto, Igor; Kamenskii, Alexander; Mukhin, Ivan S; Lipovskii, Andrey A

    2016-01-01

    The paper is dedicated to the recently developed by the authors technique of silver nanoisland growth, allowing self-arrangement of 2D-patterns of nanoislands. The technique employs silver out-diffusion from ion-exchanged glass in the course of annealing in hydrogen. To modify the silver ion distribution in the exchanged soda-lime glass we included the thermal poling of the ion-exchanged glass with a profiled electrode as an intermediate stage of the process. The resulting consequence consists of three steps: (i) during the ion exchange of the glass in the AgxNa1-xNO3 (x = 0.01-0.15) melt we enrich the subsurface layer of the glass with silver ions; (ii) under the thermal poling, the electric field displaces these ions deeper into the glass under the 2D profiled anodic electrode, the displacement is smaller under the hollows in the electrode where the intensity of the field is minimal; (iii) annealing in a reducing atmosphere of hydrogen results in silver out-diffusion only in the regions corresponding to the electrode hollows, as a result silver forms nanoislands following the shape of the electrode. Varying the electrode and mode of processing allows governing the nanoisland size distribution and self-arrangement of the isolated single nanoislands, pairs, triples or groups of several nanoislands-so-called plasmonic molecules.

  4. Design and testing of the first 2D Prototype Vertically Integrated Pattern Recognition Associative Memory

    Energy Technology Data Exchange (ETDEWEB)

    Liu, T.; Deptuch, G.; Hoff, J.; Jindariani, S.; Joshi, S.; Olsen, J.; Tran, N.; Trimpl, M.

    2015-02-01

    An associative memory-based track finding approach has been proposed for a Level 1 tracking trigger to cope with increasing luminosities at the LHC. The associative memory uses a massively parallel architecture to tackle the intrinsically complex combinatorics of track finding algorithms, thus avoiding the typical power law dependence of execution time on occupancy and solving the pattern recognition in times roughly proportional to the number of hits. This is of crucial importance given the large occupancies typical of hadronic collisions. The design of an associative memory system capable of dealing with the complexity of HL-LHC collisions and with the short latency required by Level 1 triggering poses significant, as yet unsolved, technical challenges. For this reason, an aggressive R&D program has been launched at Fermilab to advance state of-the-art associative memory technology, the so called VIPRAM (Vertically Integrated Pattern Recognition Associative Memory) project. The VIPRAM leverages emerging 3D vertical integration technology to build faster and denser Associative Memory devices. The first step is to implement in conventional VLSI the associative memory building blocks that can be used in 3D stacking, in other words, the building blocks are laid out as if it is a 3D design. In this paper, we report on the first successful implementation of a 2D VIPRAM demonstrator chip (protoVIPRAM00). The results show that these building blocks are ready for 3D stacking.

  5. Hydrothermal synthesis of 2D MoS 2 nanosheets for electrocatalytic hydrogen evolution reaction

    KAUST Repository

    Muralikrishna, S.

    2015-10-20

    Nanostructured molybdenum disulfide (MoS) is a very promising catalyst for producing molecular hydrogen by electrochemical methods. Herein, we have designed and synthesized highly electocatalytically active 2D MoS nanosheets (NS) from molybdenum trioxide (MoO) by a facile hydrothermal method and have compared their electrocatalytic activities for hydrogen evolution reaction (HER). The electrochemical characterization was performed using linear sweep voltammetry (LSV) in acidic medium. The MoS NS show a HER onset potential at about 80 mV vs. reversible hydrogen electrode (RHE) which is much lower than MoO (300 mV). The MoS NS and MoO show a current density of 25 mA cm and 0.3 mA cm, respectively at an overpotential of 280 mV vs. RHE. The MoS NS showed an 83 times higher current density when compared to MoO. The Tafel slopes of the MoS NS and MoO were about 90 mV per dec and 110 mV per dec respectively. This suggests that MoS NS are a better electrocatalyst when compared to MoO and follow the Volmer-Heyrovsky mechanism for HER.

  6. Evolution of Raman G and G'(2D) Modes in Folded Graphene Layers

    CERN Document Server

    Cong, Chunxiao

    2013-01-01

    Bernal- and non-Bernal-stacked graphene layers have been systematically studied by Raman imaging and spectroscopy. Two dominant Raman modes, G and G'(or 2D) of folded graphene layers exhibit three types of spectral features when interlayer lattice mismatch, defined by a rotational angle varies. Among these folded graphene layers, the most interesting one is the folded graphene layers that present an extremely strong G mode enhanced by a twist-induced Van Hove singularities. The evolution of Raman G and G' modes of such folded graphene layers are probed by changing the excitation photon energies. For the first time, doublet splitting of the G' mode in folded double-layer (1 + 1) and the G mode in folded tetra-layer (2 + 2) graphene are clearly observed. The G' mode splitting in folded double-layer graphene is attributed to the coexistence of inner and outer scattering processes and the trigonal warping effect. While the two peaks of the G mode in folded tetra-layer graphene are assigned to Raman-active mode (E...

  7. Dead Reckoning Using Play Patterns in a Simple 2D Multiplayer Online Game

    Directory of Open Access Journals (Sweden)

    Wei Shi

    2014-01-01

    Full Text Available In today’s gaming world, a player expects the same play experience whether playing on a local network or online with many geographically distant players on congested networks. Because of delay and loss, there may be discrepancies in the simulated environment from player to player, likely resulting in incorrect perception of events. It is desirable to develop methods that minimize this problem. Dead reckoning is one such method. Traditional dead reckoning schemes typically predict a player’s position linearly by assuming players move with constant force or velocity. In this paper, we consider team-based 2D online action games. In such games, player movement is rarely linear. Consequently, we implemented such a game to act as a test harness we used to collect a large amount of data from playing sessions involving a large number of experienced players. From analyzing this data, we identified play patterns, which we used to create three dead reckoning algorithms. We then used an extensive set of simulations to compare our algorithms with the IEEE standard dead reckoning algorithm and with the recent “Interest Scheme” algorithm. Our results are promising especially with respect to the average export error and the number of hits.

  8. Improved 2D Intelligent Driver Model simulating synchronized flow and evolution concavity in traffic flow

    CERN Document Server

    Tian, Junfang; Li, Geng; Treiber, Martin; Zhu, Chenqiang; Jia, Bin

    2016-01-01

    This paper firstly show that 2 Dimensional Intelligent Driver Model (Jiang et al., PloS one, 9(4), e94351, 2014) is not able to replicate the synchronized traffic flow. Then we propose an improved model by considering the difference between the driving behaviors at high speeds and that at low speeds. Simulations show that the improved model can reproduce the phase transition from synchronized flow to wide moving jams, the spatiotemporal patterns of traffic flow induced by traffic bottleneck, and the evolution concavity of traffic oscillations (i.e. the standard deviation of the velocities of vehicles increases in a concave/linear way along the platoon). Validating results show that the empirical time series of traffic speed obtained from Floating Car Data can be well simulated as well.

  9. High Luminescence White LEDs Prepared with 2D Island-Pattern of Quantum Dots Dispersed Photopolymer Films

    Directory of Open Access Journals (Sweden)

    Hyun-Guk Hong

    2015-01-01

    Full Text Available Since the reabsorption loss among different size quantum dots (QDs is a critical issue in the QD based white LEDs, we proposed and fabricated new film structure of 2D island-patterns consisting of separate green and red QDs dispersed photopolymer patterns in a zigzag form. A small air-gap such as 60 μm between QD islands helps to control the optical path at the interface to reduce the lateral reabsorption loss to enhance the optical efficiency of white LED. The 2D island-patterns of QD phosphor film were fabricated using a UV imprinting process and compared the optical efficiency with the other QD film structure prepared with same QD concentrations and thicknesses such as a mixed and separately layered QD structure. Experimental and simulation analysis were performed to confirm the better optical efficiency from the 2D island-patterns of QD films due to the reduced reabsorption loss. High luminescence white LED was finally realized with 2D island-patterns of QD film, resulting in a luminous efficiency of 62.2 lm/W and CRI of 83 with CCT of 4537 K at the operation current of 60 mA.

  10. 2D nanosheet molybdenum disulphide (MoS2) modified electrodes explored towards the hydrogen evolution reaction.

    Science.gov (United States)

    Rowley-Neale, Samuel J; Brownson, Dale A C; Smith, Graham C; Sawtell, David A G; Kelly, Peter J; Banks, Craig E

    2015-11-21

    We explore the use of two-dimensional (2D) MoS2 nanosheets as an electrocatalyst for the Hydrogen Evolution Reaction (HER). Using four commonly employed commercially available carbon based electrode support materials, namely edge plane pyrolytic graphite (EPPG), glassy carbon (GC), boron-doped diamond (BDD) and screen-printed graphite electrodes (SPE), we critically evaluate the reported electrocatalytic performance of unmodified and MoS2 modified electrodes towards the HER. Surprisingly, current literature focuses almost exclusively on the use of GC as an underlying support electrode upon which HER materials are immobilised. 2D MoS2 nanosheet modified electrodes are found to exhibit a coverage dependant electrocatalytic effect towards the HER. Modification of the supporting electrode surface with an optimal mass of 2D MoS2 nanosheets results in a lowering of the HER onset potential by ca. 0.33, 0.57, 0.29 and 0.31 V at EPPG, GC, SPE and BDD electrodes compared to their unmodified counterparts respectively. The lowering of the HER onset potential is associated with each supporting electrode's individual electron transfer kinetics/properties and is thus distinct. The effect of MoS2 coverage is also explored. We reveal that its ability to catalyse the HER is dependent on the mass deposited until a critical mass of 2D MoS2 nanosheets is achieved, after which its electrocatalytic benefits and/or surface stability curtail. The active surface site density and turn over frequency for the 2D MoS2 nanosheets is determined, characterised and found to be dependent on both the coverage of 2D MoS2 nanosheets and the underlying/supporting substrate. This work is essential for those designing, fabricating and consequently electrochemically testing 2D nanosheet materials for the HER.

  11. EXPRESSION PATTERN OF LUNG CANCER RELATED GENES IN MALIGNANT TRANSFORMATION OF BEP2D

    Institute of Scientific and Technical Information of China (English)

    范保星; 张开泰; 李刚; 谢玲; 马淑华; 葛世丽; 项小琼; 胡迎春; 王升启; 周平坤; 吴德昌

    2002-01-01

    Objective: To detect the expression difference of 60 lung cancer associated genes in human bronchial epithelial malignant transformation cell model (BEP2D) induced by alpha-particles. Methods: 60 lung cancer associated genes were collected and micro-arrayed onto the microscope slides using Cartesian PixSys5500 cDNA Microarray machine. Total RNA from BEP2D cells and passage 20 (Rl5H-20), passage 35 (R15H-35) cells derived from BEP2D following 1.5 Gy alpha-particles was extracted and labeled by fluorescent dye. The labeled probe was then hybridized with the cDNA. Results: 40, 47, 20 genes were detected in BEP2D, R15H-20 and R15H-35 respectively. The expression level of tumor suppressor genes decreased greatly in the transformed R15H-35. Most oncogenes decreased slightly in R15H-20. Most growth factors expressed only in R15H-20. Conclusion: In human bronchial epithelial malignant transformed cell model generated by alpha-particles, the loss-function of tumor suppressor genes at initiation stage was dominant, some related oncogenes and growth factors promoted the malignant transformation.

  12. A physical pattern recognition approach for 2D electromagnetic induction studies

    Directory of Open Access Journals (Sweden)

    D. Patella

    2000-06-01

    Full Text Available We present a new tomographic procedure for the analysis of natural source electromagnetic (EM induction field data collected over any complex 2D buried structure beneath a flat air-earth boundary. The tomography is developed in a pure physical context and the primary goal is the depiction of the space distribution of two occurrence probability functions for the induced electrical charge accumulations on resistivity discontinuities and current channelling inside conductive bodies, respectively. The procedure to obtain tomographic image consists of a scanning operation governed analytically by a set of multiple interference cross-correlations between the observed EM components and the corresponding synthetic components of a pair of elementary charge and dipole. To show the potentiality of the proposed physical tomography, we discuss the results from three 2D synthetic examples.

  13. MADS-box gene evolution - structure and transcription patterns

    DEFF Research Database (Denmark)

    Johansen, Bo; Pedersen, Louise Buchholt; Skipper, Martin;

    2002-01-01

    Mads-box genes, ABC model, Evolution, Phylogeny, Transcription patterns, Gene structure, Conserved motifs......Mads-box genes, ABC model, Evolution, Phylogeny, Transcription patterns, Gene structure, Conserved motifs...

  14. Phenols content and 2-D electrophoresis protein pattern: a promising tool to monitor Posidonia meadows health state

    Directory of Open Access Journals (Sweden)

    Randazzo Davide

    2007-07-01

    Full Text Available Abstract Background The endemic seagrass Posidonia oceanica (L. Delile colonizes soft bottoms producing highly productive meadows that play a crucial role in coastal ecosystems dynamics. Human activities and natural events are responsible for a widespread meadows regression; to date the identification of "diagnostic" tools to monitor conservation status is a critical issue. In this study the feasibility of a novel tool to evaluate ecological impacts on Posidonia meadows has been tested. Quantification of a putative stress indicator, i.e. phenols content, has been coupled to 2-D electrophoretic protein analysis of rhizome samples. Results The overall expression pattern from Posidonia rhizome was determined using a preliminary proteomic approach, 437 protein spots were characterized by pI and molecular weight. We found that protein expression differs in samples belonging to sites with high or low phenols: 22 unique protein spots are peculiar of "low phenols" and 27 other spots characterize "high phenols" samples. Conclusion Posidonia showed phenols variations within the meadow, that probably reflect the heterogeneity of environmental pressures. In addition, comparison of the 2-D electrophoresis patterns allowed to highlight qualitative protein expression differences in response to these pressures. These differences may account for changes in metabolic/physiological pathways as adaptation to stress. A combined approach, based on phenols content determination and 2-D electrophoresis protein pattern, seems a promising tool to monitor Posidonia meadows health state.

  15. Experimental stabilisation of 2D vortex patterns using time-dependent forcing

    NARCIS (Netherlands)

    Lauret, M.; Kamp, L. P. J.; van Heijst, G. J. F.; M.R. de Baar,; Nijmeijer, H.

    2013-01-01

    Experimental results of the effect of time-periodic and “chirped” (electro-magnetic) forcing on vortex patterns in shallow-water-layer flows are presented. Analogously to vibrational control, the use of a time-periodic forcing results in stabilisation of otherwise unstable vortex patterns. Chirped f

  16. 2D spatially controlled polymer micro patterning for cellular behavior studies

    Science.gov (United States)

    Dinca, V.; Palla-Papavlu, A.; Paraico, I.; Lippert, T.; Wokaun, A.; Dinescu, M.

    2011-04-01

    A simple and effective method to functionalize glass surfaces that enable polymer micropatterning and subsequent spatially controlled adhesion of cells is reported in this paper. The method involves the application of laser induced forward transfer (LIFT) to achieve polymer patterning in a single step onto cell repellent substrates (i.e. polyethyleneglycol (PEG)). This approach was used to produce micron-size polyethyleneimine (PEI)-patterns alternating with cell-repellent areas. The focus of this work is the ability of SH-SY5Y human neuroblastoma cells to orient, migrate, and produce organized cellular arrangements on laser generated PEI patterns.

  17. NUMERICAL TESTS ON PATTERN FORMATION IN 2D HETEROGENEOUS MEDIUMS: AN APPROACH USING THE SCHNAKENBERG MODEL

    Directory of Open Access Journals (Sweden)

    DIEGO A. GARZÓN-ALVARADO

    2012-01-01

    Full Text Available Este articulo presenta distintas pruebas numéricas en dominios que presenta variación de parámetros, de forma espacial, de la ecuación de reacción- difusión en el espacio de Turing. Las pruebas son desarrolladas en cuadrados de lado unitario 2D en el cual se realizan subdivisiones (subdominios. En cada subdomminio se ingresan parámetros que corresponden a los diferentes números de onda, por lo tanto presentan un medio heterogéneo. Cada número de onda fue predicho mediante la teoría lineal de estabilidad y corresponde a diferentes patrones de Turing. La ecuación de reacción elegida es Schnakenberg. Los resultados muestran patrones complejos de bandas mixtas y puntos, además, los patrones no corresponden a los patrones originales en cada subdominio.

  18. 2D spiral pattern recognition based on neural network covering algorithm

    Institute of Scientific and Technical Information of China (English)

    HUANG Guo-hong; XIONG Zhi-hua; SHAO Hui-he

    2007-01-01

    The main aim for a 2D spiral recognition algorithm is to learn to discriminate between data distributed on two distinct strands in the x - y plane. This problem is of critical importance since it incorporates temporal characteristics often found in real-time applications. Previous work with this benchmark has witnessed poor results with statistical methods such as discriminant analysis and tedious procedures for better results with neural networks. This paper presents a max-density covering learning algorithm based on constructive neural networks which is efficient in terms of the recognition rate and the speed of recognition. The results show that it is possible to solve the spiral problem instantaneously (up to 100% correct classification on the test set).

  19. The algorithm of decomposing superimposed 2-D Poisson processes and its application to the extracting earthquake clustering pattern

    Institute of Scientific and Technical Information of China (English)

    裴韬; 周成虎; 杨明; 骆剑承; 李全林

    2004-01-01

    Aiming at the complexity of seismic gestation mechanism and spatial distribution, we hypothesize that the seismic data are composed of background earthquakes and anomaly earthquakes in a certain temporal-spatial scope. Also the background earthquakes and anomaly earthquakes both satisfy the 2-D Poisson process of different parameters respectively. In the paper, the concept of N-th order distance is introduced in order to transform 2-D superimposed Poisson process into 1-D mixture density function. On the basis of choosing the distance, mixture density function is decomposed to recognize the anomaly earthquakes through genetic algorithm. Combined with the temporal scanning of C value, the algorithm is applied to the recognition on spatial pattern of foreshock anomalies by examples of Songpan and Longling sequences in the southwest of China.

  20. The Spitzer c2d Legacy Results: Star Formation Rates and Efficiencies; Evolution and Lifetimes

    CERN Document Server

    Evans, Neal J; Jørgensen, Jes K; Enoch, Melissa L; Merín, Bruno; van Dishoeck, Ewine F; Alcalá, Juan M; Myers, Philip C; Stapelfeldt, Karl R; Huard, Tracy L; Allen, Lori E; Harvey, Paul M; van Kempen, Tim; Blake, Geoffrey A; Koerner, David W; Mundy, Lee G; Padgett, Deborah L; Sargent, Anneila I

    2008-01-01

    (Abridged) The c2d Spitzer Legacy project obtained images and photometry with both IRAC and MIPS instruments for five large, nearby molecular clouds. This paper combines information drawn from studies of individual clouds into a combined and updated statistical analysis of star formation rates and efficiencies, numbers and lifetimes for SED classes, and clustering properties. Current star formation efficiencies range from 3% to 6%. Taken together, the five clouds are producing about 260 solar masses of stars per Myr. The star formation surface density is more than an order of magnitude larger than would be predicted from the Kennicutt relation used in extragalactic studies. Measured against the dense gas probed by the maps of dust continuum emission, the efficiencies are much higher, and the current stock of dense cores would be exhausted in 1.8 Myr on average. The derived lifetime for the Class I phase is 0.44 to 0.54 Myr, considerably longer than some estimates. Similarly, the lifetime for the Class 0 SED c...

  1. Pattern recognition using invariants defined from higher order spectra: 2-D image inputs.

    Science.gov (United States)

    Chandran, V; Carswell, B; Boashash, B; Elgar, S

    1997-01-01

    A new algorithm for extracting features from images for object recognition is described. The algorithm uses higher order spectra to provide desirable invariance properties, to provide noise immunity, and to incorporate nonlinearity into the feature extraction procedure thereby allowing the use of simple classifiers. An image can be reduced to a set of 1D functions via the Radon transform, or alternatively, the Fourier transform of each 1D projection can be obtained from a radial slice of the 2D Fourier transform of the image according to the Fourier slice theorem. A triple product of Fourier coefficients, referred to as the deterministic bispectrum, is computed for each 1D function and is integrated along radial lines in bifrequency space. Phases of the integrated bispectra are shown to be translation- and scale-invariant. Rotation invariance is achieved by a regrouping of these invariants at a constant radius followed by a second stage of invariant extraction. Rotation invariance is thus converted to translation invariance in the second step. Results using synthetic and actual images show that isolated, compact clusters are formed in feature space. These clusters are linearly separable, indicating that the nonlinearity required in the mapping from the input space to the classification space is incorporated well into the feature extraction stage. The use of higher order spectra results in good noise immunity, as verified with synthetic and real images. Classification of images using the higher order spectra-based algorithm compares favorably to classification using the method of moment invariants.

  2. Patterns and Processes of Vertebrate Evolution

    Science.gov (United States)

    Carroll, Robert Lynn

    1997-04-01

    This new text provides an integrated view of the forces that influence the patterns and rates of vertebrate evolution from the level of living populations and species to those that resulted in the origin of the major vertebrate groups. The evolutionary roles of behavior, development, continental drift, and mass extinctions are compared with the importance of variation and natural selection that were emphasized by Darwin. It is extensively illustrated, showing major transitions between fish and amphibians, dinosaurs and birds, and land mammals to whales. No book since Simpson's Major Features of Evolution has attempted such a broad study of the patterns and forces of evolutionary change. Undergraduate students taking a general or advanced course on evolution, and graduate students and professionals in evolutionary biology and paleontology will find the book of great interest.

  3. New adaptive routing pattern for 2D Mesh structure%2D Mesh结构中一种新的自适应路由模式

    Institute of Scientific and Technical Information of China (English)

    张麟麟; 李东生; 雍爱霞

    2012-01-01

    针对2D Mesh拓扑结构中的损坏节点会导致静态XY路由算法无法有效传输的问题,提出了一种新的路由算法——FTXY路由算法.首先对网络拓扑结构中的平均延时、理想平均吞吐量和能量消耗进行了理论评估,然后在NIRGAM仿真软平台上采用FTXY路由算法对上述三个参数进行验证,并与XY路由算法进行比较.实验结果显示,新的路由算法可以有效地绕过损坏节点,并且不会造成阻塞,提高了网络的传输性能.%For the problem that the static XY routing algorithm could not transmit effectively on account of the damaged nodes in 2D Mesh topology, this paper introduced a new routing algorithm; FTXY routing algorithm. Firstly,it evaluated the average latency, average throughput and the energy consumption theoretically, then used FTXY routing algorithm to validate the above three parameters in NIRGAM software, and compared with the XY routing algorithm. The experimental results show that the new routing algorithm can effectively round the damaged nodes and it cannot induce block, thus improving the transmission performance of the network.

  4. Formation and 2D-patterning of silver nanoisland film using thermal poling and out-diffusion from glass

    Science.gov (United States)

    Chervinskii, S.; Sevriuk, V.; Reduto, I.; Lipovskii, A.

    2013-12-01

    We fabricated silver nanoisland films and patterned silver nanoisland films using out-diffusion of silver from glass in the course of the ion-exchanged glass substrate annealing in reducing hydrogen atmosphere. The choice of the annealing conditions allows to provide prevailing of silver nanoisland formation over the formation of silver nanoparticles in the bulk of the glass. The procedure of the patterned film formation includes (i) silver-sodium ion exchange in the glass, (ii) thermal poling of the ion-exchanged glass with a profiled anodic electrode, and (iii) annealing the glass in hydrogen. The formation of silver nanoislands in unpoled regions on the glass surface allowed us to avoid any post-processing of very fragile silver island film in formation of 2D-patterned nanoisland structures. Poling of the glass with properly profiled electrode was used for the formation of random chains and ordered arrays of separate silver nanoislands. Depending on processing parameters, a typical island size in the films and chains varied from several to tens of nanometers, and was down to 200 nm in the arrays.

  5. Temporal evolution of magma flow and degassing conditions during dome growth, insights from 2D numerical modeling

    Science.gov (United States)

    Chevalier, Laure; Collombet, Marielle; Pinel, Virginie

    2017-03-01

    Understanding magma degassing evolution during an eruption is essential to improving forecasting of effusive/explosive regime transitions at andesitic volcanoes. Lava domes frequently form during effusive phases, inducing a pressure increase both within the conduit and within the surrounding rocks. To quantify the influence of dome height on magma flow and degassing, we couple magma and gas flow in a 2D numerical model. The deformation induced by magma flow evolution is also quantified. From realistic initial magma flow conditions in effusive regime (Collombet, 2009), we apply increasing pressure at the conduit top as the dome grows. Since volatile solubility increases with pressure, dome growth is then associated with an increase in magma dissolved water content at a given depth, which corresponds with a decrease in magma porosity and permeability. Magma flow evolution is associated with ground deflation of a few μrad in the near field. However this signal is not detectable as it is hidden by dome subsidence (a few mrad). A Darcy flow model is used to study the impact of pressure and permeability conditions on gas flow in the conduit and surrounding rock. We show that dome permeability has almost no influence on magma degassing. However, increasing pressure in the surrounding rock, due to dome loading, as well as decreasing magma permeability in the conduit limit permeable gas loss at the conduit walls, thus causing gas pressurization in the upper conduit by a few tens of MPa. Decreasing magma permeability and increasing gas pressure increase the likelihood of magma explosivity and hazard in the case of a rapid decompression due to dome collapse.

  6. Evaluation of spatial and temporal root water uptake patterns of a flood-irrigated pecan tree using the hydrus (2D/3D) model

    OpenAIRE

    Deb, SK; Shukla, MK; J. Šimůnek; Mexal, JG

    2013-01-01

    Quantitative information about the spatial and temporal patterns of compensatory root water uptake (RWU) in flood-irrigated pecan orchard is limited. We evaluated spatio-temporal compensated and uncompensated RWU patterns of mature pecan tree in a silty clay loam orchard using the HYDRUS (2D/3D) model. HYDRUS (2D/3D) simulations, which agreed well with measured water contents and temperatures at different soil depths and horizontal distances from the tree trunk, suggested that while both comp...

  7. Novel patterns of cancer genome evolution

    Institute of Scientific and Technical Information of China (English)

    Xia Zhang; Xiaodi Deng; Yu Zhang; Zhiguang Li

    2015-01-01

    Cells usually undergo a long journey of evolution during the progression from normal to precancerous cells and finally to full-fledged cancer cells. Multiple genomic aberrations are acquired during this journey that could either act as drivers to confer significant growth advantages or act as passengers with little effect on the tumor growth. Recent advances in sequencing technology have made it feasible to decipher the evolutionary course of a cancer cell on a genome-wide level by evaluating the relative number of mutated alleles. Novel terms such as chromothripsis and chromoplexy have been introduced to describe the newly identified patterns of cancer genome evolution. These new insights have greatly expanded our understanding of the initiation and progression of cancers, which should aid in improving the efficiency of cancer management and treatment.

  8. Orbital evolution of colliding star and pulsar winds in 2D and 3D: dimensionality, resolution, and grid size effects

    CERN Document Server

    Bosch-Ramon, V; Perucho, M

    2014-01-01

    The structure formed by the shocked winds of a massive star and a non-accreting pulsar in a binary system suffers periodic and random variations of orbital and non-linear dynamical origin. The characterization of the evolution of the two-wind interaction region is necessary to understand the non-thermal emission from radio to gamma rays. For the first time, we simulate in 3D the interaction of isotropic stellar and relativistic pulsar winds along one full orbit, on scales well beyond the binary size. We also investigate the impact of grid resolution and size. We carry out, with the code PLUTO, relativistic hydrodynamical simulations in 2 and 3D of the interaction of a slow dense wind and a mildly relativistic wind along one full orbit, up to ~100 times the binary size. The 2-dimensional simulations are carried out with equal and larger grid resolution and size than in 3D. The simulations in 3D confirm previous results in 2D, showing a strong shock induced by Coriolis forces that terminates the pulsar wind in ...

  9. Divide and Conquer Approach to Contact Map Overlap Problem Using 2D-Pattern Mining of Protein Contact Networks.

    Science.gov (United States)

    Koneru, Suvarna Vani; Bhavani, Durga S

    2015-01-01

    A novel approach to Contact Map Overlap (CMO) problem is proposed using the two dimensional clusters present in the contact maps. Each protein is represented as a set of the non-trivial clusters of contacts extracted from its contact map. The approach involves finding matching regions between the two contact maps using approximate 2D-pattern matching algorithm and dynamic programming technique. These matched pairs of small contact maps are submitted in parallel to a fast heuristic CMO algorithm. The approach facilitates parallelization at this level since all the pairs of contact maps can be submitted to the algorithm in parallel. Then, a merge algorithm is used in order to obtain the overall alignment. As a proof of concept, MSVNS, a heuristic CMO algorithm is used for global as well as local alignment. The divide and conquer approach is evaluated for two benchmark data sets that of Skolnick and Ding et al. It is interesting to note that along with achieving saving of time, better overlap is also obtained for certain protein folds.

  10. Mining Botnets and Their Evolution Patterns

    Institute of Scientific and Technical Information of China (English)

    Jaehoon Choi; Jaewoo Kang; Jinseung Lee; Chihwan Song; Qingsong Jin; Sunwon Lee; Jinsun Uh

    2013-01-01

    The botnet is the network of compromised computers that have fallen under the control of hackers after being infected by malicious programs such as trojan viruses.The compromised machines are mobilized to perform various attacks including mass spamming,distributed denial of service (DDoS) and additional trojans.This is becoming one of the most serious threats to the Internet infrastructure at present.We introduce a method to uncover compromised machines and characterize their behaviors using large email logs.We report various spam campaign variants with different characteristics and introduce a statistical method to combine them.We also report the long-term evolution patterns of the spam campaigns.

  11. Centimeter Scale Patterned Growth of Vertically Stacked Few Layer Only 2D MoS2/WS2 van der Waals Heterostructure

    Science.gov (United States)

    Choudhary, Nitin; Park, Juhong; Hwang, Jun Yeon; Chung, Hee-Suk; Dumas, Kenneth H.; Khondaker, Saiful I.; Choi, Wonbong; Jung, Yeonwoong

    2016-05-01

    Two-dimensional (2D) van der Waal (vdW) heterostructures composed of vertically-stacked multiple transition metal dichalcogenides (TMDs) such as molybdenum disulfide (MoS2) and tungsten disulfide (WS2) are envisioned to present unprecedented materials properties unobtainable from any other material systems. Conventional fabrications of these hybrid materials have relied on the low-yield manual exfoliation and stacking of individual 2D TMD layers, which remain impractical for scaled-up applications. Attempts to chemically synthesize these materials have been recently pursued, which are presently limited to randomly and scarcely grown 2D layers with uncontrolled layer numbers on very small areas. Here, we report the chemical vapor deposition (CVD) growth of large-area (>2 cm2) patterned 2D vdW heterostructures composed of few layer, vertically-stacked MoS2 and WS2. Detailed structural characterizations by Raman spectroscopy and high-resolution/scanning transmission electron microscopy (HRTEM/STEM) directly evidence the structural integrity of two distinct 2D TMD layers with atomically sharp vdW heterointerfaces. Electrical transport measurements of these materials reveal diode-like behavior with clear current rectification, further confirming the formation of high-quality heterointerfaces. The intrinsic scalability and controllability of the CVD method presented in this study opens up a wide range of opportunities for emerging applications based on the unconventional functionalities of these uniquely structured materials.

  12. Identification of characteristic ELM evolution patterns with Alfven-scale measurements and unsupervised machine learning analysis

    Science.gov (United States)

    Smith, David R.; Fonck, R. J.; McKee, G. R.; Diallo, A.; Kaye, S. M.; Leblanc, B. P.; Sabbagh, S. A.

    2016-10-01

    Edge localized mode (ELM) saturation mechanisms, filament dynamics, and multi-mode interactions require nonlinear models, and validation of nonlinear ELM models requires fast, localized measurements on Alfven timescales. Recently, we investigated characteristic ELM evolution patterns with Alfven-scale measurements from the NSTX/NSTX-U beam emission spectroscopy (BES) system. We applied clustering algorithms from the machine learning domain to ELM time-series data. The algorithms identified two or three groups of ELM events with distinct evolution patterns. In addition, we found that the identified ELM groups correspond to distinct parameter regimes for plasma current, shape, magnetic balance, and density pedestal profile. The observed characteristic evolution patterns and corresponding parameter regimes suggest genuine variation in the underlying physical mechanisms that influence the evolution of ELM events and motivate nonlinear MHD simulations. Here, we review the previous results for characteristic ELM evolution patterns and parameter regimes, and we report on a new effort to explore the identified ELM groups with 2D BES measurements and nonlinear MHD simulations. Supported by U.S. Department of Energy Award Numbers DE-SC0001288 and DE-AC02-09CH11466.

  13. Evolution of sexual dimorphism in the digit ratio 2D:4D--relationships with body size and microhabitat use in iguanian lizards.

    Directory of Open Access Journals (Sweden)

    Camilla M Gomes

    Full Text Available The ratio between lengths of digit II and IV (digit ratio 2D:4D is a morphological feature that likely affects tetrapod locomotor performances in different microhabitats. Modifications of this trait may be triggered by changes in steroids concentrations during embryo development, which might reflect direct selection acting on digit ratio or be solely a consequence of hormonal differences related for example to body size. Here we apply both conventional and phylogenetic analyses on morphological data from 25 lizard species of 3 families of Iguania (Iguanidae, Polychrotidae, and Tropiduridae, in order to verify whether selective pressures related to locomotion in different microhabitats could override the prenatal developmental cues imposed on the digit ratio 2D:4D by differences in body size between males and females. Data suggest that this trait evolved in association with ecological divergence in the species studied, despite the clear effect of body size on the digit ratio 2D:4D. The ecological associations of size-corrected digit ratios were restricted to one sex, and females of species that often use perches exhibited small digit ratios in the front limbs, which translated into larger sexual dimorphism indexes of arboreal species. The results, together with the subsequent discussion, provide outlines for further investigation about possible developmental mechanisms related to the evolution of adaptive changes in digit lengths that may have occurred during the evolution of ecological divergence in squamates.

  14. Statistical Description of Pattern Evolution in Damage- Fracture

    Institute of Scientific and Technical Information of China (English)

    夏蒙棼; 白以龙; 柯孚久

    1994-01-01

    A model of dynamical process and stochastic jump has been put forward to study the pattern evolution in damage-fracture According to the final states of evolution processes,the evolution modes can he classified as globally stable modes (GS modes) and evolution induced catastrophic modes (EIC modes); the latter are responsible for fracture A statistical description is introduced to clarify the pattern eolution in this paper It is indicated that the appearance of fracture in disordered materials should be depicted In probability distribution function.

  15. A numerical investigation of the evolution of 2-D disturbances in hypersonic boundary layers and the effect on the flow structure due to the existence of shocklets

    Institute of Scientific and Technical Information of China (English)

    CAO; Wei; ZHOU; Heng

    2004-01-01

    The evolution of 2-D disturbances in hypersonic boundary layer with Mach number 6,8, and 10 was investigated numerically by three different numerical schemes.At the entrance, second mode T-S waves with different amplitudes were introduced, and the relation between the Mach number and the amplitude of the disturbance when shocklets started to appear was investigated. By comparing the disturbance velocity profiles with those provided by linear stability theory, the effects of shocklets on flow structures were also investigated.

  16. Numerical investigation of flow and thermal pattern in unbounded flow using nanofluid - Case study: Laminar 2-D plane jet

    Directory of Open Access Journals (Sweden)

    Armaghani Taher

    2016-01-01

    Full Text Available In this article, a numerical study is carried out to analyze the effect of nanoparticle volume fraction over flow and thermal characteristics of laminar 2-D plane jet. Al2O3-water and TiO2-water nanofluids are considered in this investigation with lowest and highest values of particle volume concentration equals to 0 and 0.02 respectively. This paper propose four correlations for describing the relation between the solid volume fraction, δt and δu. The results show that the cross stream thermal diffusion depth and cross stream hydraulic diffusion depth are increased when particles volume concentration is increased and mean temperature and mean velocity decreases when the solid volume fraction is increased. The effects of nanoparticle volume fraction in velocity and temperature time histories are also studied and discussed.

  17. Calibrating OPC model with full CD profile data for 2D and 3D patterns using scatterometry

    Science.gov (United States)

    Dave, Aasutosh D.; Kritsun, Oleg; Deng, Yunfei; Yoshimoto, Kenji; Li, Jie; Hu, Jiangtao

    2009-03-01

    The ability to manage critical dimensions (CDs) of structures on IC devices is vital to improving product yield and performance. It is challenging to achieve accurate metrology data as the geometries shrink beyond 40 nm features. At this technology node CDSEM noise and resist LER are of significant concerns1. This paper examines the extendibility of scatterometry techniques to characterize structures that are close to limits of lithographic printing and to extract full profile information for 2D and 3D features for OPC model calibration2. The resist LER concerns are diminished because of the automatic averaging that scatterometry provides over the measurement pad; this represents a significant added value for proper OPC model calibration and verification. This work develops a comparison matrix to determine the impact of scatterometry data on OPC model calibration with conventional CDSEM measurements. The paper will report test results for the OPC model through process data for accuracy and predictability.

  18. Exploring the evolution of investment pattern on advanced manufacturing technology

    DEFF Research Database (Denmark)

    Yang, Cheng; Matthiesen, Rikke Vestergaard; Johansen, John

    2014-01-01

    This paper explores the evolution of investment pattern on advanced manufacturing technology in a manner that builds on a longitudinal perspective. Based on the data of investments in AMTs from 567 manufacturing companies this paper develops a longitudinal taxonomy defined by the evolution...

  19. Vitamin D [1,25(OH)2D3] Differentially Regulates Human Innate Cytokine Responses to Bacterial versus Viral Pattern Recognition Receptor Stimuli.

    Science.gov (United States)

    Fitch, Natascha; Becker, Allan B; HayGlass, Kent T

    2016-04-01

    Vitamin D plays multiple roles in regulation of protective and maladaptive immunity. Although epidemiologic studies link poor in vivo 25(OH)D status to increased viral respiratory infections, we poorly understand how vitamin D affects viral pattern recognition receptor (PRR)-driven cytokine production. In this study, we hypothesized that the biologically active metabolite of vitamin D, 1,25(OH)2D3, inhibits human proinflammatory and anti-inflammatory innate cytokine responses stimulated by representative bacterial or viral PRR ligands. Fresh PBMCs or CD14(+) monocytes were stimulated with TLR4, TLR7/8-selective ligands, or respiratory syncytial virus (RSV) ± 1,25(OH)2D3. Proinflammatory and anti-inflammatory responses resulting from TLR4 stimulation were inhibited ∼50% in the presence of 1,25(OH)2D3. Conversely, its usage at physiologic through pharmacologic concentrations inhibited neither proinflammatory nor anti-inflammatory responses evoked by viral PRR ligands or infectious RSV. This differential responsiveness was attributed to the finding that TLR7/8, but not TLR4, stimulation markedly inhibited vitamin D receptor mRNA and protein expression, selectively reducing the sensitivity of viral PRR responses to modulation. 1,25(OH)2D3 also enhanced expression of IkBa, a potent negative regulator of NF-κB and cytokine production, in TLR4-stimulated monocytes while not doing so upon TLR7/8 stimulation. Thus, 1,25(OH)2D3 inhibits both proinflammatory and a broad panel of anti-inflammatory responses elicited by TLR4 stimulation, arguing that the common view of it as an anti-inflammatory immune response modifier is an oversimplification. In viral responses, it consistently fails to modify TLR7/8- or RSV-stimulated innate cytokine production, even at supraphysiologic concentrations. Collectively, the data call into question the rationale for increasingly widespread self-medication with vitamin D supplements.

  20. A coupled 2$\\times$2D Babcock-Leighton solar dynamo model. I. Surface magnetic flux evolution

    CERN Document Server

    Lemerle, Alexandre; Carignan-Dugas, Arnaud

    2015-01-01

    The need for reliable predictions of the solar activity cycle motivates the development of dynamo models incorporating a representation of surface processes sufficiently detailed to allow assimilation of magnetographic data. In this series of papers we present one such dynamo model, and document its behavior and properties. This first paper focuses on one of the model's key components, namely surface magnetic flux evolution. Using a genetic algorithm, we obtain best-fit parameters of the transport model by least-squares minimization of the differences between the associated synthetic synoptic magnetogram and real magnetographic data for activity cycle 21. Our fitting procedure also returns Monte Carlo-like error estimates. We show that the range of acceptable surface meridional flow profiles is in good agreement with Doppler measurements, even though the latter are not used in the fitting process. Using a synthetic database of bipolar magnetic region (BMR) emergences reproducing the statistical properties of ...

  1. Plasmonic spectrum on 1D and 2D periodic arrays of rod-shape metal nanoparticle pairs with different core patterns for biosensor and solar cell applications

    Science.gov (United States)

    Kumara, N. T. R. N.; Chou Chau, Yuan-Fong; Huang, Jin-Wei; Huang, Hung Ji; Lin, Chun-Ting; Chiang, Hai-Pang

    2016-11-01

    Simulations of surface plasmon resonance (SPR) on the near field intensity and absorption spectra of one-dimensional (1D) and two-dimensional (2D) periodic arrays of rod-shape metal nanoparticle (MNP) pairs using the finite element method (FEM) and taking into account the different core patterns for biosensor and solar cell applications are investigated. A tunable optical spectrum corresponding to the transverse SPR modes is observed. The peak resonance wavelength (λ res) can be shifted to red as the core patterns in rod-shape MNPs have been changed. We find that the 2D periodic array of core-shell MNP pairs (case 2) exhibit a red shifted SPR that can be tuned the gap enhancement and absorption efficiency simultaneously over an extended wavelength range. The tunable optical performances give us a qualitative idea of the geometrical properties of the periodic array of rod-shape MNP pairs on SPRs that can be as a promising candidate for plasmonic biosensor and solar cell applications.

  2. Pattern evolution during ion beam sputtering; reductionistic view

    Science.gov (United States)

    Kim, J.-H.; Kim, J.-S.

    2016-09-01

    The development of the ripple pattern during the ion beam sputtering (IBS) is expounded via the evolution of its constituent ripples. For that purpose, we perform numerical simulation of the ripple evolution that is based on Bradley-Harper model and its non-linear extension. The ripples are found to evolve via various well-defined processes such as ripening, averaging, bifurcation and their combinations, depending on their neighboring ripples. Those information on the growth kinetics of each ripple allow the detailed description of the pattern development in real space that the instability argument and the diffraction study both made in k-space cannot provide.

  3. Evolutions of Wave Patterns in Whitham-Broer-Kaup Equation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Zheng-Di; BI Qin-Sheng

    2009-01-01

    Upon investigation of the parameter influence on the structure of WBK equation, transition boundaries are derived. All possible bounded waves as well as the existence conditions are obtained. The evolution of waves with variation of the parameters is discussed in detail, which reveals the bifurcation mechanism between different wave patterns.

  4. Time rescaling and pattern formation in biological evolution.

    Science.gov (United States)

    Igamberdiev, Abir U

    2014-09-01

    Biological evolution is analyzed as a process of continuous measurement in which biosystems interpret themselves in the environment resulting in changes of both. This leads to rescaling of internal time (heterochrony) followed by spatial reconstructions of morphology (heterotopy). The logical precondition of evolution is the incompleteness of biosystem's internal description, while the physical precondition is the uncertainty of quantum measurement. The process of evolution is based on perpetual changes in interpretation of information in the changing world. In this interpretation the external biospheric gradients are used for establishment of new features of organization. It is concluded that biological evolution involves the anticipatory epigenetic changes in the interpretation of genetic symbolism which cannot generally be forecasted but can provide canalization of structural transformations defined by the existing organization and leading to predictable patterns of form generation.

  5. Transcriptome-wide patterns of divergence during allopatric evolution.

    Science.gov (United States)

    Pereira, Ricardo J; Barreto, Felipe S; Pierce, N Tessa; Carneiro, Miguel; Burton, Ronald S

    2016-04-01

    Recent studies have revealed repeated patterns of genomic divergence associated with species formation. Such patterns suggest that natural selection tends to target a set of available genes, but is also indicative that closely related taxa share evolutionary constraints that limit genetic variability. Studying patterns of genomic divergence among populations within the same species may shed light on the underlying evolutionary processes. Here, we examine transcriptome-wide divergence and polymorphism in the marine copepod Tigriopus californicus, a species where allopatric evolution has led to replicate sets of populations with varying degrees of divergence and hybrid incompatibility. Our analyses suggest that relatively small effective population sizes have resulted in an exponential decline of shared polymorphisms during population divergence and also facilitated the fixation of slightly deleterious mutations within allopatric populations. Five interpopulation comparisons at three different stages of divergence show that nonsynonymous mutations tend to accumulate in a specific set of proteins. These include proteins with central roles in cellular metabolism, such as those encoded in mtDNA, but also include an additional set of proteins that repeatedly show signatures of positive selection during allopatric divergence. Although our results are consistent with a contribution of nonadaptive processes, such as genetic drift and gene expression levels, generating repeatable patterns of genomic divergence in closely related taxa, they also indicate that adaptive evolution targeting a specific set of genes contributes to this pattern. Our results yield insights into the predictability of evolution at the gene level.

  6. Spectral feature extraction of EEG signals and pattern recognition during mental tasks of 2-D cursor movements for BCI using SVM and ANN.

    Science.gov (United States)

    Bascil, M Serdar; Tesneli, Ahmet Y; Temurtas, Feyzullah

    2016-09-01

    Brain computer interface (BCI) is a new communication way between man and machine. It identifies mental task patterns stored in electroencephalogram (EEG). So, it extracts brain electrical activities recorded by EEG and transforms them machine control commands. The main goal of BCI is to make available assistive environmental devices for paralyzed people such as computers and makes their life easier. This study deals with feature extraction and mental task pattern recognition on 2-D cursor control from EEG as offline analysis approach. The hemispherical power density changes are computed and compared on alpha-beta frequency bands with only mental imagination of cursor movements. First of all, power spectral density (PSD) features of EEG signals are extracted and high dimensional data reduced by principle component analysis (PCA) and independent component analysis (ICA) which are statistical algorithms. In the last stage, all features are classified with two types of support vector machine (SVM) which are linear and least squares (LS-SVM) and three different artificial neural network (ANN) structures which are learning vector quantization (LVQ), multilayer neural network (MLNN) and probabilistic neural network (PNN) and mental task patterns are successfully identified via k-fold cross validation technique.

  7. Paleogene Tectonic Evolution Controls on Sequence Stratigraphic Patterns in the Fushan Sag, Northern South China Sea

    Institute of Scientific and Technical Information of China (English)

    Guanhong Wang; Hua Wang; Huajun Gan; Entao Liu; Cunyin Xia; Yingdong Zhao; Shanbin Chen; Chengcheng Zhang

    2016-01-01

    Tectonism is of extreme importance to sequence stratigraphic patterns in continental sedimentary basins, affecting both the architectures and internal makeup of sequences. Sequence stratigraphic framework of the Paleogene system in the Fushan sag, northern South China Sea, was built using 3D and 2D seismic data, complemented by drilling cores and well logs data. One first-order, three second-order and seven third-order sequences were identified. Analysis of paleotectonic stress field, unconformities and subsidence history showed that the Paleogene tectonic evolution presented significant characteristics of multistage and episode, and can be divided into three stages: rifting stage I (initial rifting period), rifting stage II (rapid subsidence period), rifting stage III (fault-depressed diver-sionary period). Partition of the west and east in tectonic activity was obvious. The west area showed relatively stronger tectonic activity than the east area, especially during the rifting stage II. Episodic rifting and lateral variations in tectonic activity resulted in a wide variety of structural slope break belts, which controlled both the sequence architectures and interval makeup, and strongly constrained the development of special facies zones or sand bodies that tended to form hydrocarbon accumulation. This paper classifies the genetic types of slope break belts and their relevant sequence stratigraphic patterns within the Fushan sag, and further discusses the tectonic evolution controls on sequence stratigraphic patterns, which suggests that vertical evolution paths of structural slope break belts and relevant sequence stratigraphic patterns as a response to the Paleogene tectonic evolution were strongly controlled by sag margin types and lateral variations of tectonic activity.

  8. Evolution of central pattern generators and rhythmic behaviours.

    Science.gov (United States)

    Katz, Paul S

    2016-01-01

    Comparisons of rhythmic movements and the central pattern generators (CPGs) that control them uncover principles about the evolution of behaviour and neural circuits. Over the course of evolutionary history, gradual evolution of behaviours and their neural circuitry within any lineage of animals has been a predominant occurrence. Small changes in gene regulation can lead to divergence of circuit organization and corresponding changes in behaviour. However, some behavioural divergence has resulted from large-scale rewiring of the neural network. Divergence of CPG circuits has also occurred without a corresponding change in behaviour. When analogous rhythmic behaviours have evolved independently, it has generally been with different neural mechanisms. Repeated evolution of particular rhythmic behaviours has occurred within some lineages due to parallel evolution or latent CPGs. Particular motor pattern generating mechanisms have also evolved independently in separate lineages. The evolution of CPGs and rhythmic behaviours shows that although most behaviours and neural circuits are highly conserved, the nature of the behaviour does not dictate the neural mechanism and that the presence of homologous neural components does not determine the behaviour. This suggests that although behaviour is generated by neural circuits, natural selection can act separately on these two levels of biological organization.

  9. Multi-level human evolution: ecological patterns in hominin phylogeny.

    Science.gov (United States)

    Parravicini, Andrea; Pievani, Telmo

    2016-06-20

    Evolution is a process that occurs at many different levels, from genes to ecosystems. Genetic variations and ecological pressures are hence two sides of the same coin; but due both to fragmentary evidence and to the influence of a gene-centered and gradualistic approach to evolutionary phenomena, the field of paleoanthropology has been slow to take the role of macro-evolutionary patterns (i.e. ecological and biogeographical at large scale) seriously. However, several very recent findings in paleoanthropology stress both climate instability and ecological disturbance as key factors affecting the highly branching hominin phylogeny, from the earliest hominins to the appearance of cognitively modern humans. Allopatric speciation due to geographic displacement, turnover-pulses of species, adaptive radiation, mosaic evolution of traits in several coeval species, bursts of behavioral innovation, serial dispersals out of Africa, are just some of the macro-evolutionary patterns emerging from the field. The multilevel approach to evolution proposed by paleontologist Niles Eldredge is adopted here as interpretative tool, and has yielded a larger picture of human evolution that integrates different levels of evolutionary change, from local adaptations in limited ecological niches to dispersal phenotypes able to colonize an unprecedented range of ecosystems. Changes in global climate and Earth's surface most greatly affected human evolution. Precisely because it is cognitively hard for us to appreciate the long-term common destiny we share with the whole biosphere, it is particularly valuable to highlight the accumulating evidence that human evolution has been deeply affected by global ecological changes that transformed our African continent of origin.

  10. Pattern of LNAPL's migration and distribution in 2-D auriferous media%LNAPL在二维含水介质中运移规律的研究

    Institute of Scientific and Technical Information of China (English)

    宋超; 刘财; 张宇白; 鹿琪

    2014-01-01

    In order to study the pattern of Light Non-Aqueous Phase Liquid ( LNAPL) contaminant's migration and diffusion in homogeneous aqueous media , an infinitesimal model was set to derive the dispersion equation for LNAPL contaminant in homogeneous aqueous media .The authors built different media models , numerical simulate 2-D advection-dispersion equation with finite difference method to get numerical solution , and analyzed the features of LNAPL contaminant's migration to get the pattern of LNAPL contaminant's migration and diffusion in the homoge-neous media and homogeneous layered media .The pattern of LNAPL's migration and distribution in auriferous fol-low the advection-dispersion equation , and the dispersion coefficient of media is the main factor that influences the migration of LNAPL's contaminant .%为研究LNAPL (轻质非水相液体)污染物在均匀含水介质中的运移规律,本文建立微元模型推导出LNAPL在均匀含水介质中的对流--弥散方程。针对不同的介质模型,对二维对流--弥散方程运用差分法进行数值模拟,求其数值解。分析LNAPL污染物的运移特征,得出在均匀介质和非均匀层状介质中运移规律: LNAPL污染物在含水介质中的运移规律遵循对流--弥散方程,介质的弥散系数是影响LNAPL污染物运移的主要因素。

  11. Building the backbone: the development and evolution of vertebral patterning.

    Science.gov (United States)

    Fleming, Angeleen; Kishida, Marcia G; Kimmel, Charles B; Keynes, Roger J

    2015-05-15

    The segmented vertebral column comprises a repeat series of vertebrae, each consisting of two key components: the vertebral body (or centrum) and the vertebral arches. Despite being a defining feature of the vertebrates, much remains to be understood about vertebral development and evolution. Particular controversy surrounds whether vertebral component structures are homologous across vertebrates, how somite and vertebral patterning are connected, and the developmental origin of vertebral bone-mineralizing cells. Here, we assemble evidence from ichthyologists, palaeontologists and developmental biologists to consider these issues. Vertebral arch elements were present in early stem vertebrates, whereas centra arose later. We argue that centra are homologous among jawed vertebrates, and review evidence in teleosts that the notochord plays an instructive role in segmental patterning, alongside the somites, and contributes to mineralization. By clarifying the evolutionary relationship between centra and arches, and their varying modes of skeletal mineralization, we can better appreciate the detailed mechanisms that regulate and diversify vertebral patterning.

  12. D2D Technology Development and Its Impact on Cellular Network Evolution%D2D技术发展及其对蜂窝网络演进的影响

    Institute of Scientific and Technical Information of China (English)

    周伟; 宋玉

    2013-01-01

    It discusses the hybrid cellular network based on D2D communication, application scenarios and system requirements. It also discusses the implementation of LTE-D2D, analyzes the impact on network evolution and business model.%阐述了以端到端直通通信(D2D)为代表的混合蜂窝网络技术及应用场景、系统需求,探讨了LTE-D2D实现方案,分析了D2D对蜂窝网络和现商业模式的冲击。

  13. The evolution of isochore patterns in vertebrate genomes

    Directory of Open Access Journals (Sweden)

    Cammarano Rosalia

    2009-04-01

    Full Text Available Abstract Background Previous work from our laboratory showed that (i vertebrate genomes are mosaics of isochores, typically megabase-size DNA segments that are fairly homogeneous in base composition; (ii isochores belong to a small number of families (five in the human genome characterized by different GC levels; (iii isochore family patterns are different in fishes/amphibians and mammals/birds, the latter showing GC-rich isochore families that are absent or very scarce in the former; (iv there are two modes of genome evolution, a conservative one in which isochore patterns basically do not change (e.g., among mammalian orders, and a transitional one, in which they do change (e.g., between amphibians and mammals; and (v isochores are tightly linked to a number of basic biological properties, such as gene density, gene expression, replication timing and recombination. Results The present availability of a number of fully sequenced genomes ranging from fishes to mammals allowed us to carry out investigations that (i more precisely quantified our previous conclusions; (ii showed that the different isochore families of vertebrate genomes are largely conserved in GC levels and dinucleotide frequencies, as well as in isochore size; and (iii isochore family patterns can be either conserved or change within both warm- and cold-blooded vertebrates. Conclusion On the basis of the results presented, we propose that (i the large conservation of GC levels and dinucleotide frequencies may reflect the conservation of chromatin structures; (ii the conservation of isochore size may be linked to the role played by isochores in chromosome structure and replication; (iii the formation, the maintainance and the changes of isochore patterns are due to natural selection.

  14. Genetics and evolution of colour patterns in reptiles.

    Science.gov (United States)

    Olsson, Mats; Stuart-Fox, Devi; Ballen, Cissy

    2013-01-01

    The study of coloration in the polyphyletic reptilians has flourished in the last two decades, in particular with respect to the underlying genetics of colour traits, the function of colours in social interactions, and ongoing selection on these traits in the wild. The taxonomic bias, however, is profound: at this level of resolution almost all available information is for diurnal lizards. Therefore, we focus on case studies, for which there are as complete causal sequences of colour evolution as possible, from phenotypic expression of variation in colour, to ongoing selection in the wild. For work prior to 1992 and for a broader coverage of reptilian coloration we refer the readers to Cooper and Greenburg's (Biology of the Reptilia, 1992) review. There are seven major conclusions we would like to emphasise: (a) visual systems in diurnal lizards are broadly conserved but among the wider range of reptiles in general, there is functionally important variation in the number and type of photoreceptors, spectral tuning of photopigments and optical properties of the eye; (b) coloration in reptiles is a function of complex interactions between structural and pigmentary components, with implications for both proximate control and condition dependence of colour expression; (c) studies of colour-variable species have enabled estimates of heritability of colour and colour patterns, which often show a simple Mendelian pattern of inheritance; (d) colour-polymorphic lizard species sometimes, but not always, show striking differences in genetically encoded reproductive tactics and provide useful models for studying the evolution and maintenance of polymorphism; (e) both male and female colours are sometimes, but not always, a significant component of socio-sexual signalling, often based on multiple traits; (f) evidence for effects of hormones and condition on colour expression, and trade-offs with immunocompetence and parasite load, is variable; (g) lizards show fading of colours

  15. Evolution of dissolution patterns by mixing corrosion in karst systems

    Science.gov (United States)

    Cabeza, Yoar; Hidalgo, Juan J.; Dentz, Marco; Carrera, Jesús

    2014-05-01

    Conduit enlargement in a karst system is usually assumed to be controlled by non-linear kinetics that allow aggressive water to penetrate along fractures (Gabrovšek and Dreybrodt, 2000, Water. Resour. Res.). However, other mechanism known as mixing corrosion may be decisive for the geometry of the resulting dissolution patterns, at least at depth. Mixing corrosion is caused by the renovation of the dissolution capacity that happens when two waters saturated with respect to calcite but with different CO2 partial pressure mix. In this case, the reaction rate is mixing-controlled and can be quantified in terms of the mixing proportion of the conservative components of the chemical system (De Simoni et al. 2005, Water. Resour. Res.). Therefore, the porosity creation governed by the reaction rate will depend on the chemical differences between the end members and by the degree of mixing. The aim of this work is to study the evolution of the porosity and permeability within a carbonate matrix by mixing-driven dissolution under different diffusion regimes. The speciation of the chemical system is calculated using CHEPROO. Flow and transport are modeled using an ad hoc code that accounts for feedback between reactions, porosity creation and permeability changes. The effects of the initial porosity field, water chemistry and the resulting geometry of the dissolution patterns are explored for different scenarios.

  16. Evolution of anthropoid jaw loading and kinematic patterns.

    Science.gov (United States)

    Ravosa, M J; Vinyard, C J; Gagnon, M; Islam, S A

    2000-08-01

    Major transformations in the skull and masticatory system characterized the evolution of crown anthropoids. To offer further insight into the phylogenetic and arguably adaptive significance of specific primate mandibular loading and kinematic patterns, allometric analyses of metric parameters linked to masticatory function are performed within and between 47 strepsirhine and 45 recent anthropoid species. When possible, basal anthropoids are considered. These results are subsequently integrated with prior experimental and morphological work on primate skull form. As compared to strepsirhines, crown anthropoids have a vertically longer ascending ramus linked to a glenoid and condyle positioned relatively higher above the occlusal plane. Interestingly, anthropoids and strepsirhines do not exhibit different mean ratios of condylar to glenoid height, which suggests that both clades are similar in their ability to evenly distribute occlusal contacts and perhaps forces along the postcanine teeth. Thus, given the considerable suborder differences in the scaling of both glenoid and condylar height, we argue that much of this variation in jaw-joint height is linked to suborder differences in relative facial height due in turn to increased encephalization, basicranial flexion, and facial kyphosis in anthropoids. Due to a more elongate ascending ramus, anthropoids evince more vertically oriented masseters than like-sized strepsirhines. Having a relatively longer ramus and a more medially displaced lateral pterygoid plate, crown anthropoids exhibit medial pterygoids oriented similar to those of strepsirhines, but with a variably longer lever arm. As anthropoid masseters are less advantageously placed to effect transverse movements/forces, we argue that balancing-side deep-masseter activity underlying a wishboning loading regime serves to increase, or at least maintain, transverse levels of jaw movement and occlusal force at the end of the masticatory power stroke. Crown

  17. Peak alignment using wavelet pattern matching and differential evolution.

    Science.gov (United States)

    Zhang, Zhi-Min; Chen, Shan; Liang, Yi-Zeng

    2011-01-30

    Retention time shifts badly impair qualitative or quantitative results of chemometric analyses when entire chromatographic data are used. Hence, chromatograms should be aligned to perform further analysis. Being inspired and motivated by this purpose, a practical and handy peak alignment method (alignDE) is proposed, implemented in this research for one-way chromatograms, which basically consists of five steps: (1) chromatogram lengths equalization using linear interpolation; (2) accurate peak pattern matching by continuous wavelet transform (CWT) with the Mexican Hat and Haar wavelets as its mother wavelets; (3) flexible baseline fitting utilizing penalized least squares; (4) peak clustering when gap of two peaks is smaller than a certain threshold; (5) peak alignment using differential evolution (DE) to maximize linear correlation coefficient between reference signal and signal to be aligned. This method is demonstrated with both simulated chromatograms and real chromatograms, for example, chromatograms of fungal extracts and Red Peony Root obtained by HPLC-DAD. It is implemented in R language and available as open source software to a broad range of chromatograph users (http://code.google.com/p/alignde).

  18. [Metamorphosis in the Urodelan amphibians: patterns, regulation mechanisms, and evolution].

    Science.gov (United States)

    Smirnov, S V

    2006-01-01

    Patterns of metamorphosis and mechanisms of its regulation in primitive and advanced salamanders are compared. It is found that urodelan evolution was characterised by the following trends: 1) increase in the number of metamorphosing systems; 2) increase in the amplitude of metamorphic transformations of each particular system due to the progressive divergence of the larval and the adult morphology; 3) synchronization of metamorphic transformations and their concentration within a relatively short period of ontogeny; 4) increase in the role of the thyroid hormones (TH) in the regulation of metamorphosis. Structures that are induced by factors other than TH and develop independently of TH in primitive Urodela species acquire TH-dependence in phyletically more advanced salamanders. For instance, morphogenetic induction as a mechanism of ontogeny regulation is substituted by endocrine induction with TH as the inducing factor. The switch from morphogenetic to endocrine induction stimulates the following events: 1) optimization of ontogeny; 2) reduction of the metamorphosis duration; 3) formation of the dissociability of larval and post-metamorphic stages of ontogeny, which, in its turn, is a precondition for the swith to necrobiotic metamorphosis and to the direct development.

  19. Time evolution of the diffraction pattern of an ultrashort laser pulse.

    Science.gov (United States)

    Lefrancois, M; Pereira, S

    2003-05-19

    An analytical expression for the time evolution of the diffraction pattern of an ultrashort laser pulse passing through a circular aperture is obtained in the Fresnel regime. The diffraction is not constant in time as the pulse travels through the aperture. This may have implications in experiments involving fast dynamics. Examples of the evolution of the diffraction pattern are given.

  20. Alternate pathways of body shape evolution translate into common patterns of locomotor evolution in two clades of lizards.

    Science.gov (United States)

    Bergmann, Philip J; Irschick, Duncan J

    2010-06-01

    Body shape has a fundamental impact on organismal function, but it is unknown how functional morphology and locomotor performance and kinematics relate across a diverse array of body shapes. We showed that although patterns of body shape evolution differed considerably between lizards of the Phrynosomatinae and Lerista, patterns of locomotor evolution coincided between clades. Specifically, we found that the phrynosomatines evolved a stocky phenotype through body widening and limb shortening, whereas Lerista evolved elongation through body lengthening and limb shortening. In both clades, relative limb length played a key role in locomotor evolution and kinematic strategies, with long-limbed species moving faster and taking longer strides. In Lerista, the body axis also influenced locomotor evolution. Similar patterns of locomotor evolution were likely due to constraints on how the body can move. However, these common patterns of locomotor evolution between the two clades resulted in different kinematic strategies and levels of performance among species because of their morphological differences. Furthermore, we found no evidence that distinct body shapes are adaptations to different substrates, as locomotor kinematics did not change on loose or solid substrates. Our findings illustrate the importance of studying kinematics to understand the mechanisms of locomotor evolution and phenotype-function relationships.

  1. The warm ionized gas in CALIFA early-type galaxies: 2D emission-line patterns and kinematics for 32 galaxies

    CERN Document Server

    Gomes, J M; Kehrig, C; Vílchez, J M; Lehnert, M D; Sánchez, S F; Ziegler, B; Breda, I; Reis, S N dos; Iglesias-Páramo, J; Bland-Hawthorn, J; Galbany, L; Bomans, D J; Rosales-Ortega, F F; Fernandes, R Cid; Walcher, C J; Falcón-Barroso, J; García-Benito, R; Márquez, I; del Olmo, A; Masegosa, J; Mollá, M; Marino, R A; Delgado, R M González; López-Sánchez, Á R

    2015-01-01

    The morphological, spectroscopic and kinematical properties of the warm interstellar medium (wim) in early-type galaxies (ETGs) hold key observational constraints to nuclear activity and the buildup history of these massive, quiescent systems. High-quality integral field spectroscopy (IFS) data with a wide spectral and spatial coverage, such as those from the CALIFA survey, offer an unprecedented opportunity for advancing our understanding of the wim in ETGs. This article centers on a 2D investigation of the wim component in 32 nearby (<~150Mpc) ETGs from CALIFA, complementing a previous 1D analysis of the same sample (Papaderos et al. 2013; P13). We include here H\\alpha\\ intensity and equivalent width (EW) maps and radial profiles, diagnostic emission-line ratios, besides ionized-gas and stellar kinematics. This study is supplemented by \\tau-ratio maps as an efficient means to quantify the role of photoionization by pAGB stars, as compared to other mechanisms (e.g., AGN, low-level star formation). Additio...

  2. Comparisons of Damage Evolution between 2D C/SiC and SiC/SiC Ceramic-Matrix Composites under Tension-Tension Cyclic Fatigue Loading at Room and Elevated Temperatures

    Directory of Open Access Journals (Sweden)

    Longbiao Li

    2016-10-01

    Full Text Available In this paper, comparisons of damage evolution between 2D C/SiC and SiC/SiC ceramic-matrix composites (CMCs under tension–tension cyclic fatigue loading at room and elevated temperatures have been investigated. Fatigue hysteresis loops models considering multiple matrix cracking modes in 2D CMCs have been developed based on the damage mechanism of fiber sliding relative to the matrix in the interface debonded region. The relationships between the fatigue hysteresis loops, fatigue hysteresis dissipated energy, fatigue peak stress, matrix multiple cracking modes, and interface shear stress have been established. The effects of fiber volume fraction, fatigue peak stress and matrix cracking mode proportion on fatigue hysteresis dissipated energy and interface debonding and sliding have been analyzed. The experimental fatigue hysteresis dissipated energy of 2D C/SiC and SiC/SiC composites at room temperature, 550 °C, 800 °C, and 1100 °C in air, and 1200 °C in vacuum corresponding to different fatigue peak stresses and cycle numbers have been analyzed. The interface shear stress degradation rate has been obtained through comparing the experimental fatigue hysteresis dissipated energy with theoretical values. Fatigue damage evolution in C/SiC and SiC/SiC composites has been compared using damage parameters of fatigue hysteresis dissipated energy and interface shear stress degradation rate. It was found that the interface shear stress degradation rate increases at elevated temperature in air compared with that at room temperature, decreases with increasing loading frequency at room temperature, and increases with increasing fatigue peak stress at room and elevated temperatures.

  3. An evolution model of dislocation patterns in plastic deformation and its applications

    Institute of Scientific and Technical Information of China (English)

    高维林; 白光润; 周志敏

    1995-01-01

    By combining the classic dislocation theory with the principle of dissipative structure and synergetics, an evolution model of dislocation patterns has been developed. Using this model, the evolution of dislocation patterns and the corresponding mechanical behavior have been analyzed, discussed and simulated under different deformation conditions of constant strain rate, creep and static recovery. As one of the most essential problems in the plastic deformation, the evolution of dislocation patterns has been dealt with by using non-linear methods. Results show that various problems in plastic deformation may be solved in a unified theoretical framework.

  4. Dynamical patterning modules: a "pattern language" for development and evolution of multicellular form.

    Science.gov (United States)

    Newman, Stuart A; Bhat, Ramray

    2009-01-01

    This article considers the role played by a core set of "dynamical patterning modules" (DPMs) in the origination, development and evolution of complex organisms. These consist of the products of a subset of the genes of what has come to be known as the "developmental-genetic toolkit" in association with physical processes they mobilize. The physical processes are those characteristic of chemically and mechanically excitable mesoscopic systems like cell aggregates: cohesion, viscoelasticity, diffusion, spatiotemporal heterogeneity based on activator-inhibitor interaction, and multistable and oscillatory dynamics. We focus on the emergence of the Metazoa, and show how toolkit gene products and pathways that pre-existed the metazoans acquired novel morphogenetic functions simply by virtue of the change in scale and context inherent to multicellularity. We propose that DPMs, acting singly and in combination with each other, constitute a "pattern language" capable of generating all metazoan body plans and organ forms. This concept implies that the multicellular organisms of the late Precambrian-early Cambrian were phenotypically plastic, fluently exploring morphospace in a fashion decoupled from both function-based selection and genotypic change. The relatively stable developmental trajectories and morphological phenotypes of modern organisms, then, are considered to be products of stabilizing selection. This perspective solves the apparent "molecular homology-analogy paradox," whereby widely divergent modern animal types utilize the same molecular toolkit during development, but it does so by inverting the neo-Darwinian principle that phenotypic disparity was generated over long periods of time in concert with, and in proportion to genotypic change.

  5. Binary Bell Polynomials, Bilinear Approach to Exact Periodic Wave Solutions of (2 d- 1)-Dimensional Nonlinear Evolution Equations

    Institute of Scientific and Technical Information of China (English)

    王云虎; 陈勇

    2011-01-01

    In the present letter, we get the appropriate bilinear forms of (2 + 1)-dimensional KdV equation, extended (2 + 1)-dimensional shallow water wave equation and (2 + 1)-dimensional Sawada -Kotera equation in a quick and natural manner, namely by appling the binary Bell polynomials. Then the Hirota direct method and Riemann theta function are combined to construct the periodic wave solutions of the three types nonlinear evolution equations. And the corresponding figures of the periodic wave solutions are given. Furthermore, the asymptotic properties of the periodic wave solutions indicate that the soliton solutions can be derived from the periodic wave solutions.

  6. Small phase pattern 2D beam steering and a single LCOS design of 40 1 × 12 stacked wavelength selective switches.

    Science.gov (United States)

    Yang, Haining; Robertson, Brian; Wilkinson, Peter; Chu, Daping

    2016-05-30

    Two-dimensional beam steering by small, square, phase patterns as small as 50 × 50 pixels on a phase-only liquid crystal on silicon (LCOS) device is experimentally verified as suitable for the application of wavelength selective switches (WSSs), in terms of the diffraction efficiency and steering accuracy. This enables a proposed highly functional and versatile stacked switch architecture, where 40 independent 1 × 12 WSSs can be realised on a single 4k LCOS device. They can be configured to support a 1 × N WSSs with N≤144, or an N × N wavelength crossconnect with N≤12.

  7. Land use pattern evolution and optimization in the Farming-Pastoral Zone of Northern China

    Institute of Scientific and Technical Information of China (English)

    CHEN; Yunhao; SU; Wei; WU; Yongfeng; YU; Xiaomin; ZHANG; Jinshui

    2006-01-01

    Using information about the land cover of the Farming-Pastoral Zone of Northern China retrieved from multi-temporal NOAA/AVHRR and SPOT VEGETAN images obtained in 1989, 1994 and 1999, the authors analyzed land-use pattern evolution over this 10-year period and built a land-use pattern simulation model, based on which land-use pattern evolution and optimization modeling in this region were studied. Results showed that the proposed model can effectively simulate regional land-use patterns and help improve regional ecological environments.

  8. Discovering local patterns of co - evolution: computational aspects and biological examples

    Directory of Open Access Journals (Sweden)

    Tuller Tamir

    2010-01-01

    Full Text Available Abstract Background Co-evolution is the process in which two (or more sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn about the functional interdependencies between sets of genes and cellular functions and to predict physical interactions. More generally, it can be used for answering fundamental questions about the evolution of biological systems. Orthologs that exhibit a strong signal of co-evolution in a certain part of the evolutionary tree may show a mild signal of co-evolution in other branches of the tree. The major reasons for this phenomenon are noise in the biological input, genes that gain or lose functions, and the fact that some measures of co-evolution relate to rare events such as positive selection. Previous publications in the field dealt with the problem of finding sets of genes that co-evolved along an entire underlying phylogenetic tree, without considering the fact that often co-evolution is local. Results In this work, we describe a new set of biological problems that are related to finding patterns of local co-evolution. We discuss their computational complexity and design algorithms for solving them. These algorithms outperform other bi-clustering methods as they are designed specifically for solving the set of problems mentioned above. We use our approach to trace the co-evolution of fungal, eukaryotic, and mammalian genes at high resolution across the different parts of the corresponding phylogenetic trees. Specifically, we discover regions in the fungi tree that are enriched with positive evolution. We show that metabolic genes exhibit a remarkable level of co-evolution and different patterns of co-evolution in various biological datasets. In addition, we find that protein complexes that are related to gene expression exhibit non-homogenous levels of co-evolution across different parts of the fungi evolutionary line. In the case of mammalian evolution

  9. Influence of Intrusive vs. Extrusive Magmatism on Venus' Tectonics and long-term Mantle Evolution: 2D and 3D Simulations

    Science.gov (United States)

    Tackley, P. J.

    2014-12-01

    Here we extend the numerical convection models of Venus models of [1], which included melting, magmatism, decaying heat-producing elements, core cooling, realistic temperature-dependent viscosity and either stagnant lid or episodic lithospheric overturn. In [1] it was found that for stagnant lid convection the dominant mode of heat loss is magmatic heat pipe, which requires massive magmatism and produces very thick, cold crust, inconsistent with observations. In contrast, episodic lid overturn interspersed by periods of quiescence effectively loses Venus's heat while giving lower rates of volcanism and a thinner crust. Calculations predict 5-8 overturn events over Venus's history, each lasting ˜150 Myr, initiating in one place and then spreading globally. Venus-like amplitudes of topography and geoid can be produced in either stagnant or episodic modes, with a viscosity profile that is Earth-like but shifted to higher values. Here we extend [1] by considering intrusive magmatism as an alternative to the purely extrusive magmatism previously assumed. Intrusive magmatism warms and weakens the crust, resulting in substantial surface deformation and a thinner crust. This is further enhanced by using a basaltic rheology for the crust instead of assuming the same rheological parameters as for the mantle. In some cases massive intrusive magmatism can even lead to episodic lithospheric overturn events without plastic yielding. Here we quantitatively analyse the resulting surface deformation and other signatures, and compare to observations in order to constrain the likely ratio of intrusive to extrusive magmatism. [1] Armann, M., and P. J. Tackley (2012), Simulating the thermochemical magmatic and tectonic evolution of Venus's mantle and lithosphere: Two-dimensional models, J. Geophys. Res., 117, E12003, doi:10.1029/2012JE004231.

  10. Pigment cell interactions and differential xanthophore recruitment underlying zebrafish stripe reiteration and Danio pattern evolution.

    Science.gov (United States)

    Patterson, Larissa B; Bain, Emily J; Parichy, David M

    2014-11-06

    Fishes have diverse pigment patterns, yet mechanisms of pattern evolution remain poorly understood. In zebrafish, Danio rerio, pigment-cell autonomous interactions generate dark stripes of melanophores that alternate with light interstripes of xanthophores and iridophores. Here, we identify mechanisms underlying the evolution of a uniform pattern in D. albolineatus in which all three pigment cell classes are intermingled. We show that in this species xanthophores differentiate precociously over a wider area, and that cis regulatory evolution has increased expression of xanthogenic Colony Stimulating Factor-1 (Csf1). Expressing Csf1 similarly in D. rerio has cascading effects, driving the intermingling of all three pigment cell classes and resulting in the loss of stripes, as in D. albolineatus. Our results identify novel mechanisms of pattern development and illustrate how pattern diversity can be generated when a core network of pigment-cell autonomous interactions is coupled with changes in pigment cell differentiation.

  11. Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs.

    Science.gov (United States)

    Green, Richard E; Braun, Edward L; Armstrong, Joel; Earl, Dent; Nguyen, Ngan; Hickey, Glenn; Vandewege, Michael W; St John, John A; Capella-Gutiérrez, Salvador; Castoe, Todd A; Kern, Colin; Fujita, Matthew K; Opazo, Juan C; Jurka, Jerzy; Kojima, Kenji K; Caballero, Juan; Hubley, Robert M; Smit, Arian F; Platt, Roy N; Lavoie, Christine A; Ramakodi, Meganathan P; Finger, John W; Suh, Alexander; Isberg, Sally R; Miles, Lee; Chong, Amanda Y; Jaratlerdsiri, Weerachai; Gongora, Jaime; Moran, Christopher; Iriarte, Andrés; McCormack, John; Burgess, Shane C; Edwards, Scott V; Lyons, Eric; Williams, Christina; Breen, Matthew; Howard, Jason T; Gresham, Cathy R; Peterson, Daniel G; Schmitz, Jürgen; Pollock, David D; Haussler, David; Triplett, Eric W; Zhang, Guojie; Irie, Naoki; Jarvis, Erich D; Brochu, Christopher A; Schmidt, Carl J; McCarthy, Fiona M; Faircloth, Brant C; Hoffmann, Federico G; Glenn, Travis C; Gabaldón, Toni; Paten, Benedict; Ray, David A

    2014-12-12

    To provide context for the diversification of archosaurs--the group that includes crocodilians, dinosaurs, and birds--we generated draft genomes of three crocodilians: Alligator mississippiensis (the American alligator), Crocodylus porosus (the saltwater crocodile), and Gavialis gangeticus (the Indian gharial). We observed an exceptionally slow rate of genome evolution within crocodilians at all levels, including nucleotide substitutions, indels, transposable element content and movement, gene family evolution, and chromosomal synteny. When placed within the context of related taxa including birds and turtles, this suggests that the common ancestor of all of these taxa also exhibited slow genome evolution and that the comparatively rapid evolution is derived in birds. The data also provided the opportunity to analyze heterozygosity in crocodilians, which indicates a likely reduction in population size for all three taxa through the Pleistocene. Finally, these data combined with newly published bird genomes allowed us to reconstruct the partial genome of the common ancestor of archosaurs, thereby providing a tool to investigate the genetic starting material of crocodilians, birds, and dinosaurs.

  12. Color pattern evolution in Vanessa butterflies (Nymphalidae: Nymphalini): non-eyespot characters.

    Science.gov (United States)

    Abbasi, Roohollah; Marcus, Jeffrey M

    2015-01-01

    A phylogenetic approach was used to study color pattern evolution in Vanessa butterflies. Twenty-four color pattern elements from the Nymphalid ground plan were identified on the dorsal and ventral surfaces of the fore- and hind wings. Eyespot characters were excluded and will be examined elsewhere. The evolution of each character was traced over a Bayesian phylogeny of Vanessa reconstructed from 7750 DNA base pairs from 10 genes. Generally, the correspondence between character states on the same surface of the two wings is stronger on the ventral side compared to the dorsal side. The evolution of character states on both sides of a wing correspond with each other in most extant species, but the correspondence between dorsal and ventral character states is much stronger in the forewing than in the hindwing. The dorsal hindwing of many species of Vanessa is covered with an extended Basal Symmetry System and the Discalis I pattern element is highly variable between species, making this wing surface dissimilar to the other wing surfaces. The Basal Symmetry System and Discalis I may contribute to behavioral thermoregulation in Vanessa. Overall, interspecific directional character state evolution of non-eyespot color patterns is relatively rare in Vanessa, with a majority of color pattern elements showing non-variable, non-directional, or ambiguous character state evolution. The ease with which the development of color patterns can be modified, including character state reversals, has likely made important contributions to the production of color pattern diversity in Vanessa and other butterfly groups.

  13. Interlayer couplings, Moiré patterns, and 2D electronic superlattices in MoS2/WSe2 hetero-bilayers

    Science.gov (United States)

    Zhang, Chendong; Chuu, Chih-Piao; Ren, Xibiao; Li, Ming-Yang; Li, Lain-Jong; Jin, Chuanhong; Chou, Mei-Yin; Shih, Chih-Kang

    2017-01-01

    By using direct growth, we create a rotationally aligned MoS2/WSe2 hetero-bilayer as a designer van der Waals heterostructure. With rotational alignment, the lattice mismatch leads to a periodic variation of atomic registry between individual van der Waals layers, exhibiting a Moiré pattern with a well-defined periodicity. By combining scanning tunneling microscopy/spectroscopy, transmission electron microscopy, and first-principles calculations, we investigate interlayer coupling as a function of atomic registry. We quantitatively determine the influence of interlayer coupling on the electronic structure of the hetero-bilayer at different critical points. We show that the direct gap semiconductor concept is retained in the bilayer although the valence and conduction band edges are located at different layers. We further show that the local bandgap is periodically modulated in the X-Y direction with an amplitude of ~0.15 eV, leading to the formation of a two-dimensional electronic superlattice. PMID:28070558

  14. Interlayer couplings, Moiré patterns, and 2D electronic superlattices in MoS 2 /WSe 2 hetero-bilayers

    KAUST Repository

    Zhang, Chendong

    2017-01-07

    By using direct growth, we create a rotationally aligned MoS2/WSe2 hetero-bilayer as a designer van der Waals heterostructure. With rotational alignment, the lattice mismatch leads to a periodic variation of atomic registry between individual van der Waals layers, exhibiting a Moiré pattern with a well-defined periodicity. By combining scanning tunneling microscopy/spectroscopy, transmission electron microscopy, and first-principles calculations, we investigate interlayer coupling as a function of atomic registry. We quantitatively determine the influence of interlayer coupling on the electronic structure of the hetero-bilayer at different critical points. We show that the direct gap semiconductor concept is retained in the bilayer although the valence and conduction band edges are located at different layers. We further show that the local bandgap is periodically modulated in the X-Y direction with an amplitude of ~0.15 eV, leading to the formation of a two-dimensional electronic superlattice.

  15. 2D semiconductor optoelectronics

    Science.gov (United States)

    Novoselov, Kostya

    The advent of graphene and related 2D materials has recently led to a new technology: heterostructures based on these atomically thin crystals. The paradigm proved itself extremely versatile and led to rapid demonstration of tunnelling diodes with negative differential resistance, tunnelling transistors, photovoltaic devices, etc. By taking the complexity and functionality of such van der Waals heterostructures to the next level we introduce quantum wells engineered with one atomic plane precision. Light emission from such quantum wells, quantum dots and polaritonic effects will be discussed.

  16. Evolution of spiral wave and pattern formation in a vortical polarized electric field

    Institute of Scientific and Technical Information of China (English)

    Ma Jun; Yi Ming; Li Bing-Wei; Li Yan-Long

    2008-01-01

    In this paper, the evolution of the pattern transition induced by the vortical electric field (VEF) is investigated. Firstly, a scheme is suggested to generate the VEF by changing the spatial magnetic field. Secondly, the VEF is imposed on the whole medium, and the evolutions of the spiral wave and the spatiotemporal chaos are investigated by using the numerical simulation. The result confirms that the drift and the breakup of the spiral wave and the new net-like pattern are observed when different polarized fields are imposed on the whole medium respectively. Finally, the pattern transition induced by the polarized field is discussed theoretically.

  17. Shapes of isolated domains and field induced evolution of regular and random 2D domain structures in LiNbO{sub 3} and LiTaO{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Chernykh, A. [Ferroelectric Laboratory, Ural State University, 51 Lenin Ave., 620083 Ekaterinburg (Russian Federation); Shur, V. [Ferroelectric Laboratory, Ural State University, 51 Lenin Ave., 620083 Ekaterinburg (Russian Federation)]. E-mail: vladimir.shur@usu.ru; Nikolaeva, E. [Ferroelectric Laboratory, Ural State University, 51 Lenin Ave., 620083 Ekaterinburg (Russian Federation); Shishkin, E. [Ferroelectric Laboratory, Ural State University, 51 Lenin Ave., 620083 Ekaterinburg (Russian Federation); Shur, A. [Ferroelectric Laboratory, Ural State University, 51 Lenin Ave., 620083 Ekaterinburg (Russian Federation); Terabe, K. [Advanced Material Laboratory, National Institute for Materials Science, 305-0044 Tsukuba (Japan); Kurimura, S. [Advanced Material Laboratory, National Institute for Materials Science, 305-0044 Tsukuba (Japan); Kitamura, K. [Advanced Material Laboratory, National Institute for Materials Science, 305-0044 Tsukuba (Japan); Gallo, K. [Optical Research Center, University of Southampton, Highfield, Mountbatten Bldg., SO17 1BJ Southampton (United Kingdom)

    2005-07-15

    The variety of the shapes of isolated domains, revealed in congruent and stoichiometric LiTaO{sub 3} and LiNbO{sub 3} by chemical etching and visualized by optical and scanning probe microscopy, was obtained by computer simulation. The kinetic nature of the domain shape was clearly demonstrated. The kinetics of domain structure with the dominance of the growth of the steps formed at the domain walls as a result of domain merging was investigated experimentally in slightly distorted artificial regular two-dimensional (2D) hexagonal domain structure and random natural one. The artificial structure has been realized in congruent LiNbO{sub 3} by 2D electrode pattern produced by photolithography. The polarization reversal in congruent LiTaO{sub 3} was investigated as an example of natural domain growth limited by merging. The switching process defined by domain merging was studied by computer simulation. The crucial dependence of the switching kinetics on the nuclei concentration has been revealed.

  18. Tactile perception of nonpainful unpleasantness in relation to perceived roughness: effects of inter-element spacing and speed of relative motion of rigid 2-D raised-dot patterns at two body loci.

    Science.gov (United States)

    Kitada, Ryo; Sadato, Norihiro; Lederman, Susan J

    2012-01-01

    Rigid surfaces consisting of spatially jittered 2-D raised-dot patterns with different inter-element spacings were moved back and forth across the skin at three different speeds (10-fold range). Within each psychophysical experiment, participants numerically estimated the perceived magnitude of either unpleasantness (nonpainful) or roughness of 2-D raised-dot surfaces applied to two stationary body sites (experiment 1: fingers; experiment 2: forearm). The psychophysical functions for the two types of perceptual judgment were highly similar at both body loci; more specifically, the perceived magnitude of unpleasantness and roughness both increased monotonically as a power function of increasing inter-element spacing, with the rate of growth declining at the upper end of the continuum. These results suggest that inter-element spacing is a critical determinant of the perceived magnitude of unpleasantness (nonpainful), as well as of roughness. Each perceptual judgment also increased as a function of increasing relative speed at both body loci. However, the magnitude of this effect was significantly greater for perceived unpleasantness than for perceived roughness; conversely, the speed effect was significantly greater on the forearm than on the fingers. Several possible explanations for these findings are considered.

  19. Quantitative patterns of stylistic influence in the evolution of literature

    Science.gov (United States)

    Hughes, James M.; Foti, Nicholas J.; Krakauer, David C.; Rockmore, Daniel N.

    2012-01-01

    Literature is a form of expression whose temporal structure, both in content and style, provides a historical record of the evolution of culture. In this work we take on a quantitative analysis of literary style and conduct the first large-scale temporal stylometric study of literature by using the vast holdings in the Project Gutenberg Digital Library corpus. We find temporal stylistic localization among authors through the analysis of the similarity structure in feature vectors derived from content-free word usage, nonhomogeneous decay rates of stylistic influence, and an accelerating rate of decay of influence among modern authors. Within a given time period we also find evidence for stylistic coherence with a given literary topic, such that writers in different fields adopt different literary styles. This study gives quantitative support to the notion of a literary “style of a time” with a strong trend toward increasingly contemporaneous stylistic influence. PMID:22547796

  20. Pattern and process in the evolution of learning.

    Science.gov (United States)

    Papini, Mauricio R

    2002-01-01

    A century after E. L. Thorndike's (1898) dissertation on the comparative psychology of learning, the field seems ready for a reassessment of its metatheoretical foundations. The stability of learning phenotypes across species is shown to be similar to that of other biological characters, both genotypic (e.g., Hox genes) and phenotypic (e.g., vertebrate brain structure). Moreover, an analysis of some current lines of comparative research indicates that researchers use similar strategies when approaching problems from either an ecological view (emphasizing adaptive significance) or a general-process view (emphasizing commonality across species). An integration of learning and evolution requires the development of criteria for recognizing and studying the divergence, homology, and homoplasy of learning mechanisms, much as it is done in other branches of biological research.

  1. Dental patterning in the earliest sharks: Implications for tooth evolution.

    Science.gov (United States)

    Maisey, John G; Turner, Susan; Naylor, Gavin J P; Miller, Randall F

    2014-05-01

    Doliodus problematicus is the oldest known fossil shark-like fish with an almost intact dentition (Emsian, Lower Devonian, c. 397Ma). We provide a detailed description of the teeth and dentition in D. problematicus, based on tomographic analysis of NBMG 10127 (New Brunswick Museum, Canada). Comparisons with modern shark dentitions suggest that Doliodus was a ram-feeding predator with a dentition adapted to seizing and disabling prey. Doliodus provides several clues about the early evolution of the "shark-like" dentition in chondrichthyans and also raises new questions about the evolution of oral teeth in jawed vertebrates. As in modern sharks, teeth in Doliodus were replaced in a linguo-labial sequence within tooth families at fixed positions along the jaws (12-14 tooth families per jaw quadrant in NBMG 10127). Doliodus teeth were replaced much more slowly than in modern sharks. Nevertheless, its tooth formation was apparently as highly organized as in modern elasmobranchs, in which future tooth positions are indicated by synchronized expression of shh at fixed loci within the dental epithelium. Comparable dental arrays are absent in osteichthyans, placoderms, and many "acanthodians"; a "shark-like" dentition, therefore, may be a synapomorphy of chondrichthyans and gnathostomes such as Ptomacanthus. The upper anterior teeth in Doliodus were not attached to the palatoquadrates, but were instead supported by the ethmoid region of the prechordal basicranium, as in some other Paleozoic taxa (e.g., Triodus, Ptomacanthus). This suggests that the chondrichthyan dental lamina was originally associated with prechordal basicranial cartilage as well as jaw cartilage, and that the modern elasmobranch condition (in which the oral dentition is confined to the jaws) is phylogenetically advanced. Thus, oral tooth development in modern elasmobranchs does not provide a complete developmental model for chondrichthyans or gnathostomes.

  2. On the evolution of arterial vascular patterns of tetrapods.

    Science.gov (United States)

    Farmer, C G

    2011-11-01

    The factors that explain the diverse arrangement of the major arteries of tetrapods are not known. Here, I aim to illuminate some of the underpinnings of these patterns. I review the variation in the sauropsid left, right, and dorsal aortae regarding the origin of the gastrointestinal blood vessels and the relative diameters of left and right aortae where they join together to form the dorsal aorta. I focus on these features because the quality of blood that flows through these aortae can vary depending on the state of cardiac shunting and the size of the vessel can provide insight into the quantity of blood borne by the vessels. I then place the information in a phyletic, historical, and ecological context. The plesiomorphic pattern is for the gastrointestinal vessels to arise as segmental arteries from the dorsal aorta, which is formed from the confluence of left and right aortae with similar diameters. The pattern is well conserved with only two major variations. First, in several clades of reptiles (testudines, crocodilians, lizards of the genera Varanus and Hydrosaurus) a substantial portion of the gastrointestinal arteries arises from the left aorta, leaving the diameter of the left aorta smaller than the right at their confluence. I hypothesize that this vascular arrangement facilitates growth by allowing more alkaline blood to flow to the somatic (body wall) and appendicular circulations, which may promote bone deposition and inhibit resorption, whereas hypercapnic, acidic blood flows to the digestive viscera, which may provide CO(2) as a substrate for the synthesis of gastric acid, bicarbonate, fatty acids, glutamine, purine rings, as well as glucose from lactate. Second, in some snakes and lizards with snake-like body forms, such as Amphisbaenidae, the diameters of left and right aortae are asymmetrical at their confluence with the left aorta exceeding the right, but in members of the amphibian order Gymnophiona the right generally exceeds the left. This

  3. Evolution of Web Applications with Aspect-Oriented Design Patterns

    DEFF Research Database (Denmark)

    2007-01-01

    It is more convenient to talk about changes in a domainspecific way than to formulate them at the programming construct level or-even worse-purely lexical level. Using aspect-oriented programming, changes can be modularized and made reapplicable. In this paper, selected change types in web...... applications are analyzed. They are expressed in terms of general change types which, in turn, are implemented using aspect-oriented programming. Some of general change types match aspect-oriented design patterns or their combinations....

  4. 2D numerical modelling of meandering channel formation

    Indian Academy of Sciences (India)

    Y Xiao; G Zhou; F S Yang

    2016-03-01

    A 2D depth-averaged model for hydrodynamic sediment transport and river morphological adjustment was established. The sediment transport submodel takes into account the influence of non-uniform sediment with bed surface armoring and considers the impact of secondary flow in the direction of bed-loadtransport and transverse slope of the river bed. The bank erosion submodel incorporates a simple simulation method for updating bank geometry during either degradational or aggradational bed evolution. Comparison of the results obtained by the extended model with experimental and field data, and numericalpredictions validate that the proposed model can simulate grain sorting in river bends and duplicate the characteristics of meandering river and its development. The results illustrate that by using its control factors, the improved numerical model can be applied to simulate channel evolution under differentscenarios and improve understanding of patterning processes.

  5. Depletion patterns and dust evolution in the ISM

    CERN Document Server

    Jones, A P

    1999-01-01

    We review the use of elemental depletions in determining the composition of interstellar dust and present a new interpretation of the elemental depletion patterns for the dust forming elements in a range of diffuse cloud types. We discuss this within the context of dust processing in the ISM and show that Si and Mg are selectively eroded from dust, with respect to Fe, as expected for a sputtering erosion process. However, we find that Si is preferentially and non-stoichiometrically eroded from dust with respect to Mg by some as yet unidentified process that may act in conjunction with grain sputtering. On this basis a new way of interpreting the depletions in terms of `continuous' dust processing through erosion in the interstellar medium is presented. The observed depletion patterns can then be understood in terms of a gradually changing grain chemical composition as the erosion of the atoms proceeds non-stoichiometrically in the low-density interstellar medium. The stoichiometric erosion of multicomponent (...

  6. Quantitative analysis of macroevolutionary patterning in technological evolution: Bicycle design from 1800 to 2000

    OpenAIRE

    Lake, M. W.; Venti, J.

    2009-01-01

    Book description: This volume offers an integrative approach to the application of evolutionary theory in studies of cultural transmission and social evolution and reveals the enormous range of ways in which Darwinian ideas can lead to productive empirical research, the touchstone of any worthwhile theoretical perspective. While many recent works on cultural evolution adopt a specific theoretical framework, such as dual inheritance theory or human behavioral ecology, Pattern and Process in Cu...

  7. Dorsoventral patterning in hemichordates: insights into early chordate evolution.

    Directory of Open Access Journals (Sweden)

    Christopher J Lowe

    2006-09-01

    Full Text Available We have compared the dorsoventral development of hemichordates and chordates to deduce the organization of their common ancestor, and hence to identify the evolutionary modifications of the chordate body axis after the lineages split. In the hemichordate embryo, genes encoding bone morphogenetic proteins (Bmp 2/4 and 5/8, as well as several genes for modulators of Bmp activity, are expressed in a thin stripe of ectoderm on one midline, historically called "dorsal." On the opposite midline, the genes encoding Chordin and Anti-dorsalizing morphogenetic protein (Admp are expressed. Thus, we find a Bmp-Chordin developmental axis preceding and underlying the anatomical dorsoventral axis of hemichordates, adding to the evidence from Drosophila and chordates that this axis may be at least as ancient as the first bilateral animals. Numerous genes encoding transcription factors and signaling ligands are expressed in the three germ layers of hemichordate embryos in distinct dorsoventral domains, such as pox neuro, pituitary homeobox, distalless, and tbx2/3 on the Bmp side and netrin, mnx, mox, and single-minded on the Chordin-Admp side. When we expose the embryo to excess Bmp protein, or when we deplete endogenous Bmp by small interfering RNA injections, these expression domains expand or contract, reflecting their activation or repression by Bmp, and the embryos develop as dorsalized or ventralized limit forms. Dorsoventral patterning is independent of anterior/posterior patterning, as in Drosophila but not chordates. Unlike both chordates and Drosophila, neural gene expression in hemichordates is not repressed by high Bmp levels, consistent with their development of a diffuse rather than centralized nervous system. We suggest that the common ancestor of hemichordates and chordates did not use its Bmp-Chordin axis to segregate epidermal and neural ectoderm but to pattern many other dorsoventral aspects of the germ layers, including neural cell fates

  8. Neural crest patterning and the evolution of the jaw.

    Science.gov (United States)

    Kimmel, C B; Miller, C T; Keynes, R J

    2001-01-01

    Here we present ideas connecting the behaviour of the cranial neural crest during development with the venerable, perhaps incorrect, view that gill-supporting cartilages of an ancient agnathan evolved into the skeleton of an early gnathostome's jaw. We discuss the pattern of migration of the cranial neural crest ectomesenchyme in zebrafish, along with the subsequent arrangement of postmigratory crest and head mesoderm in the nascent pharyngeal segments (branchiomeres), in diverse gnathostomes and in lampreys. These characteristics provide for a plausible von Baerian explanation for the problematic inside-outside change in topology of the gills and their supports between these 2 major groups of vertebrates. We consider it likely that the jaw supports did indeed arise from branchiomeric cartilages.

  9. Evolution and Expression Patterns of TCP Genes in Asparagales.

    Science.gov (United States)

    Madrigal, Yesenia; Alzate, Juan F; Pabón-Mora, Natalia

    2017-01-01

    CYCLOIDEA-like genes are involved in the symmetry gene network, limiting cell proliferation in the dorsal regions of bilateral flowers in core eudicots. CYC-like and closely related TCP genes (acronym for TEOSINTE BRANCHED1, CYCLOIDEA, and PROLIFERATION CELL FACTOR) have been poorly studied in Asparagales, the largest order of monocots that includes both bilateral flowers in Orchidaceae (ca. 25.000 spp) and radially symmetrical flowers in Hypoxidaceae (ca. 200 spp). With the aim of assessing TCP gene evolution in the Asparagales, we isolated TCP-like genes from publicly available databases and our own transcriptomes of Cattleya trianae (Orchidaceae) and Hypoxis decumbens (Hypoxidaceae). Our matrix contains 452 sequences representing the three major clades of TCP genes. Besides the previously identified CYC specific core eudicot duplications, our ML phylogenetic analyses recovered an early CIN-like duplication predating all angiosperms, two CIN-like Asparagales-specific duplications and a duplication prior to the diversification of Orchidoideae and Epidendroideae. In addition, we provide evidence of at least three duplications of PCF-like genes in Asparagales. While CIN-like and PCF-like genes have multiplied in Asparagales, likely enhancing the genetic network for cell proliferation, CYC-like genes remain as single, shorter copies with low expression. Homogeneous expression of CYC-like genes in the labellum as well as the lateral petals suggests little contribution to the bilateral perianth in C. trianae. CIN-like and PCF-like gene expression suggests conserved roles in cell proliferation in leaves, sepals and petals, carpels, ovules and fruits in Asparagales by comparison with previously reported functions in core eudicots and monocots. This is the first large scale analysis of TCP-like genes in Asparagales that will serve as a platform for in-depth functional studies in emerging model monocots.

  10. Evolution and Expression Patterns of TCP Genes in Asparagales

    Science.gov (United States)

    Madrigal, Yesenia; Alzate, Juan F.; Pabón-Mora, Natalia

    2017-01-01

    CYCLOIDEA-like genes are involved in the symmetry gene network, limiting cell proliferation in the dorsal regions of bilateral flowers in core eudicots. CYC-like and closely related TCP genes (acronym for TEOSINTE BRANCHED1, CYCLOIDEA, and PROLIFERATION CELL FACTOR) have been poorly studied in Asparagales, the largest order of monocots that includes both bilateral flowers in Orchidaceae (ca. 25.000 spp) and radially symmetrical flowers in Hypoxidaceae (ca. 200 spp). With the aim of assessing TCP gene evolution in the Asparagales, we isolated TCP-like genes from publicly available databases and our own transcriptomes of Cattleya trianae (Orchidaceae) and Hypoxis decumbens (Hypoxidaceae). Our matrix contains 452 sequences representing the three major clades of TCP genes. Besides the previously identified CYC specific core eudicot duplications, our ML phylogenetic analyses recovered an early CIN-like duplication predating all angiosperms, two CIN-like Asparagales-specific duplications and a duplication prior to the diversification of Orchidoideae and Epidendroideae. In addition, we provide evidence of at least three duplications of PCF-like genes in Asparagales. While CIN-like and PCF-like genes have multiplied in Asparagales, likely enhancing the genetic network for cell proliferation, CYC-like genes remain as single, shorter copies with low expression. Homogeneous expression of CYC-like genes in the labellum as well as the lateral petals suggests little contribution to the bilateral perianth in C. trianae. CIN-like and PCF-like gene expression suggests conserved roles in cell proliferation in leaves, sepals and petals, carpels, ovules and fruits in Asparagales by comparison with previously reported functions in core eudicots and monocots. This is the first large scale analysis of TCP-like genes in Asparagales that will serve as a platform for in-depth functional studies in emerging model monocots. PMID:28144250

  11. Hunting for Livelihood in Northeast Gabon: Patterns, Evolution, and Sustainability

    Directory of Open Access Journals (Sweden)

    Robert Nasi

    2008-12-01

    Full Text Available We suggest an ethno-biological approach to analyze the cultural and social drivers of hunting activities and assess sustainability in villages near Makokou, northeast Gabon, based on interviews with hunters, participatory mapping of hunting territories, and daily records of offtakes for 1 yr. Hunting in villages of northeast Gabon is practiced for both local consumption and cash income to cover basic family expenses. There appears to be no clear tendency to abandon subsistence hunting for commercial hunting as in other regions of Africa. Cultural and socioeconomic factors explain the temporal and spatial variation in hunting activities. Hunting increases in the dry season during circumcision ceremonies, when it is practiced mainly at > 10 km from villages, and decreases during the rainy season because most hunters are occupied by other economic activities. Degraded forest such as secondary regrowth supplies 20% of the animals killed and the greatest diversity of species at short distances from villages. Mature forest supplies the species with the greatest commercial value, e.g., red river hog (Potamochoerus porcus, and is the preferred source of meat for traditional ceremonies. In the last 15 yr, hunting patterns have changed rapidly, mainly because of the spread of gun hunting, which had serious implications for the nature of offtakes. Our results suggest that there is potential to allow hunting for resistant species such as blue duiker (Cephalophus monticola and African brush-tailed porcupine (Atherurus africanus. Other species such as red river hog and small diurnal monkeys require more attention. Specific management systems could be discussed in participatory hunting management plans to identify possible solutions to maintain the population levels of the more critical species.

  12. Patterns of evolution of research strands in the hydrologic sciences

    Science.gov (United States)

    Schwartz, F. W.; Fang, Y. C.; Parthasarathy, S.

    2005-03-01

    This paper examines issues of impact and innovation in groundwater research by using bibliometric data and citation analysis.The analysis is based on 3120 papers from the journal Water Resources Research with full contents and their citation data from the ISI Web of Science. The research is designed to develop a better understanding of the way citation numbers can be interpreted by scientists. Not surprisingly, the most highly cited papers appear to be pioneers in the field with papers departing significantly from what has come before and to be effective in creating similar, follow-on papers. Papers that are early contributions to a new research strand that is highly influential will be on average highly cited. However, the importance of a research strand as measured by citations seems to fall with time. The citation patterns of some classic papers show that the activity in the topical area and impact of follow-on papers gradually decline with time, which has similarities with Kuhn's ideas of revolutionary and normal science. The results of this study reinforce the importance of being a pioneer in a research strand, strategically shifting research strands, adopting strategies that can facilitate really major research breakthroughs. L'article examine les problèmes d'impact et d'innovation dans la recherche des eaux souterraines en utilisant les données bibliométriques et l'analyse des citations. L'analyse a été faite sur 3120 articles parus dans Water Resources Research en tenant compte de leur texte complet et de toutes citations parues dans l' ISI Web de la Science. Le but de la recherche a été de mieux comprendre comment le nombre des citations peut être interprété par les scientifiques. Ce n'est pas une surprise que les plus cités articles soient les articles-pionniers dans leurs domaines, qui s'écartent d'une manière significative de ce qui a été écrit auparavant et qui ont été suivi par des nouveaux articles. Les articles qui présentent une

  13. Activated sludge model No. 2d, ASM2d

    DEFF Research Database (Denmark)

    Henze, M.

    1999-01-01

    The Activated Sludge Model No. 2d (ASM2d) presents a model for biological phosphorus removal with simultaneous nitrification-denitrification in activated sludge systems. ASM2d is based on ASM2 and is expanded to include the denitrifying activity of the phosphorus accumulating organisms (PAOs......). This extension of ASM2 allows for improved modeling of the processes, especially with respect to the dynamics of nitrate and phosphate. (C) 1999 IAWQ Published by Elsevier Science Ltd. All rights reserved....

  14. A preliminary analysis of correlated evolution in Mammalian chewing motor patterns.

    Science.gov (United States)

    Williams, Susan H; Vinyard, Christopher J; Wall, Christine E; Doherty, Alison H; Crompton, Alfred W; Hylander, William L

    2011-08-01

    Descriptive and quantitative analyses of electromyograms (EMG) from the jaw adductors during feeding in mammals have demonstrated both similarities and differences among species in chewing motor patterns. These observations have led to a number of hypotheses of the evolution of motor patterns, the most comprehensive of which was proposed by Weijs in 1994. Since then, new data have been collected and additional hypotheses for the evolution of motor patterns have been proposed. Here, we take advantage of these new data and a well-resolved species-level phylogeny for mammals to test for the correlated evolution of specific components of mammalian chewing motor patterns. We focus on the evolution of the coordination of working-side (WS) and balancing-side (BS) jaw adductors (i.e., Weijs' Triplets I and II), the evolution of WS and BS muscle recruitment levels, and the evolution of asynchrony between pairs of muscles. We converted existing chewing EMG data into binary traits to incorporate as much data as possible and facilitate robust phylogenetic analyses. We then tested hypotheses of correlated evolution of these traits across our phylogeny using a maximum likelihood method and the Bayesian Markov Chain Monte Carlo method. Both sets of analyses yielded similar results highlighting the evolutionary changes that have occurred across mammals in chewing motor patterns. We find support for the correlated evolution of (1) Triplets I and II, (2) BS deep masseter asynchrony and Triplets I and II, (3) a relative delay in the activity of the BS deep masseter and a decrease in the ratio of WS to BS muscle recruitment levels, and (4) a relative delay in the activity of the BS deep masseter and a delay in the activity of the BS posterior temporalis. In contrast, changes in relative WS and BS activity levels across mammals are not correlated with Triplets I and II. Results from this work can be integrated with dietary and morphological data to better understand how feeding and the

  15. Why colour in subterranean vertebrates? Exploring the evolution of colour patterns in caecilian amphibians.

    Science.gov (United States)

    Wollenberg, K C; Measey, C John

    2009-05-01

    The proximate functions of animal skin colour are difficult to assign as they can result from natural selection, sexual selection or neutral evolution under genetic drift. Most often colour patterns are thought to signal visual stimuli; so,their presence in subterranean taxa is perplexing. We evaluate the adaptive nature of colour patterns in nearly a third of all known species of caecilians, an order of amphibians most of which live in tropical soils and leaf litter. We found that certain colour pattern elements in caecilians can be explained based on characteristics concerning above-ground movement. Our study implies that certain caecilian colour patterns have convergently evolved under selection and we hypothesize their function most likely to be a synergy of aposematism and crypsis, related to periods when individuals move overground. In a wider context, our results suggest that very little exposure to daylight is required to evolve and maintain a varied array of colour patterns in animal skin.

  16. Stability and Surface Topography Evolution in Nanoimprinted Polymer Patterns under a Thermal Gradient

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Yifu; Qi, Jerry H.; Alvine, Kyle J.; Ro, Hyun W.; Ahn, Dae Up; Lin-Gibson, Sheng; Douglas, Jack F.; Soles, Christopher L.

    2010-09-06

    Nanostructures created in polymer films by nanoimprint lithography are subject to large stresses, both those from the imprinting processes as well as stresses arising from the intrinsic thermodynamic instabilities. These stresses can induce nanostructure deformation that can compromise the intended function of the imprinted pattern. Controlling these stresses, and thus the stability of the imprinted patterns, is a key scientific issue for this technology. The requirement of film stability against dewetting requires the use of entangled polymer films, which necessitates an understanding of complex viscoelastic response of these materials to large stresses. Here we investigate the evolution of the surface topography of nanoimprinted patterns in polystyrene films through a high throughput annealing approach in which the patterns are annealed for a fixed time on a controlled temperature gradient. Using principles of time-temperature superposition we systematically explore the effect of varying basic system variables such as pattern feature size, polymer molecular mass, imprinting temperature, on nanopattern stability and on the evolution of imprinted patterns driven by surface tension and internal stress. Nanostructure collapse generally occurs through a combination of a "slumping" instability, where the imprinted film simply relaxes towards a planar film and the film height decreases with time, and a lateral "zigzag" instability in the nanoimprinted lines.

  17. Post-orogenic evolution of the Sierras Septentrionales and the Sierras Australes and links to the evolution of the eastern Argentina South Atlantic passive continental margin constrained by low temperature thermochronometry and 2D thermokinematic modeling

    Science.gov (United States)

    Kollenz, Sebastian; Glasmacher, Ulrich Anton; Rossello, Eduardo A.

    2013-04-01

    The eastern Argentina South Atlantic passive continental margin is distinguished by a very flat topography. Out of the so called Pampean flat two mountain ranges are arising. These mountain ranges, the Sierras Australes and the Sierras Septentrionales, are located in the State of Buenos Aires south of the capital Buenos Aires. North of the Sierras Septentrionales the Salado basin is located. The Sierras Septentrionales and the Sierras Australes are also divided by a smaller intracratonic basin. Further in the South the Colorado basin is located. The Sierras Australes is a variscian fold belt originated by strong phases of metamorphosis, but till now it is unclear by how many tectonic phases the area was influenced (Tomezzoli & Vilas, 1999). It consists of Proterozoic to Paleozoic rocks. The Sierras Septentrionales consists mainly of Precambrian crystalline rocks. The Precambrian sequences are overlain by younger Sediments (Cingolani, 2010). The aim is to understand the long-term landscape evolution of the area by quantifiying erosion- and exhumation-rates and by dating ancient rock-uplift-events. Another goal is to find out how the opening of the south atlantic took effect on this region. To fulfill this goal, thermochronological techniques, such as fission-track dating and (U-Th-Sm)/He dating has been applied to samples from the region. Because there was no low-temperature thermochronology done in this area, both techniques were applied on apatites and zircons. Furthermore, numerical modeling of the cooling history has provided the data base for the quantification of the exhumation rates. The first data-set shows clusters of different ages which can be linked to tectonic activities during late Paleozoic times. Also the thermokinematic modeling is leading to new insights of the evolution of both mountain ranges. References: Renata Nela Tomezzoli and Juan Francisco Vilas (1999): Palaeomagnetic constraints on the age of deformation of the Sierras Australes thrust and

  18. Dopamine D1/D5, But not D2/D3, Receptor Dependency of Synaptic Plasticity at Hippocampal Mossy Fiber Synapses that Is Enabled by Patterned Afferent Stimulation, or Spatial Learning

    Science.gov (United States)

    Hagena, Hardy; Manahan-Vaughan, Denise

    2016-01-01

    Although the mossy fiber (MF) synapses of the hippocampal CA3 region display quite distinct properties in terms of the molecular mechanisms that underlie synaptic plasticity, they nonetheless exhibit persistent (>24 h) synaptic plasticity that is akin to that observed at the Schaffer collateral (SCH)-CA1 and perforant path (PP)-dentate gyrus (DG) synapses of freely behaving rats. In addition, they also respond to novel spatial learning with very enduring forms of long-term potentiation (LTP) and long-term depression (LTD). These latter forms of synaptic plasticity are directly related to the learning behavior: novel exploration of generalized changes in space facilitates the expression of LTP at MF-CA3 synapses, whereas exploration of novel configurations of large environmental features facilitates the expression of LTD. In the absence of spatial novelty, synaptic plasticity is not expressed. Motivation is a potent determinant of whether learning about the spatial experience effectively occurs and the neuromodulator dopamine (DA) plays a key role in motivation-based learning. Prior research on the regulation by DA receptors of long-term synaptic plasticity in CA1 and DG synapses in vivo suggests that whereas D2/D3 receptors may modulate a general predisposition toward expressing plasticity, D1/D5 receptors may directly regulate the direction of change in synaptic strength that occurs during learning. Although the CA3 region is believed to play a pivotal role in many forms of learning, the role of dopamine receptors in persistent (>24 h) forms of synaptic plasticity at MF-CA3 synapses is unknown. Here, we report that whereas pharmacological antagonism of D2/D3 receptors had no impact on LTP or LTD, antagonism of D1/D5 receptors significantly impaired LTP and LTD that were induced by solely by means of patterned afferent stimulation, or LTP/LTD that are typically enhanced by the conjunction of afferent stimulation and novel spatial learning. These data indicate an

  19. Dopamine D1/D5, but not D2/D3, receptor dependency of synaptic plasticity at hippocampal mossy fiber synapses that is enabled by patterned afferent stimulation, or spatial learning

    Directory of Open Access Journals (Sweden)

    Hardy Hagena

    2016-09-01

    Full Text Available Although the mossy fiber (MF synapses of the hippocampal CA3 region display quite distinct properties in terms of the molecular mechanisms that underlie synaptic plasticity, they nonetheless exhibit persistent (>24h synaptic plasticity that is akin to that observed at the Schaffer collateral (SCH-CA1 and perforant path (PP-dentate gyrus (DG synapses of freely behaving rats. In addition, they also respond to novel spatial learning with very enduring forms of long-term potentiation (LTP and long-term depression (LTD. These latter forms of synaptic plasticity are directly related to the learning behavior: novel exploration of generalized changes in space facilitates the expression of LTP at MF-CA3 synapses, whereas exploration of novel configurations of large environmental features facilitates the expression of LTD. In the absence of spatial novelty, synaptic plasticity is not expressed. Motivation is a potent determinant of whether learning about spatial experience effectively occurs and the neuromodulator dopamine plays a key role in motivation-based learning. Prior research on the regulation by dopamine receptors of long-term synaptic plasticity in CA1 and dentate gyrus synapses in vivo suggests that whereas D2/D3 receptors may modulate a general predisposition toward expressing plasticity, D1/D5 receptors may directly regulate the direction of change in synaptic strength that occurs during learning. Although the CA3 region is believed to play a pivotal role in many forms of learning, the role of these receptors in persistent (>24h forms of synaptic plasticity at MF-CA3 synapses is unknown. Here, we report that whereas pharmacological antagonism of D2/D3 receptors had no impact on LTP or LTD, antagonism of D1/D5 receptors significantly impaired LTP and LTD that were induced by solely by means of patterned afferent stimulation, or LTP/LTD that are typically enhanced by the conjunction of afferent stimulation and novel spatial learning. These data

  20. Orthotropic Piezoelectricity in 2D Nanocellulose

    Science.gov (United States)

    García, Y.; Ruiz-Blanco, Yasser B.; Marrero-Ponce, Yovani; Sotomayor-Torres, C. M.

    2016-10-01

    The control of electromechanical responses within bonding regions is essential to face frontier challenges in nanotechnologies, such as molecular electronics and biotechnology. Here, we present Iβ-nanocellulose as a potentially new orthotropic 2D piezoelectric crystal. The predicted in-layer piezoelectricity is originated on a sui-generis hydrogen bonds pattern. Upon this fact and by using a combination of ab-initio and ad-hoc models, we introduce a description of electrical profiles along chemical bonds. Such developments lead to obtain a rationale for modelling the extended piezoelectric effect originated within bond scales. The order of magnitude estimated for the 2D Iβ-nanocellulose piezoelectric response, ~pm V‑1, ranks this material at the level of currently used piezoelectric energy generators and new artificial 2D designs. Such finding would be crucial for developing alternative materials to drive emerging nanotechnologies.

  1. Time Curves: Folding Time to Visualize Patterns of Temporal Evolution in Data.

    Science.gov (United States)

    Bach, Benjamin; Shi, Conglei; Heulot, Nicolas; Madhyastha, Tara; Grabowski, Tom; Dragicevic, Pierre

    2016-01-01

    We introduce time curves as a general approach for visualizing patterns of evolution in temporal data. Examples of such patterns include slow and regular progressions, large sudden changes, and reversals to previous states. These patterns can be of interest in a range of domains, such as collaborative document editing, dynamic network analysis, and video analysis. Time curves employ the metaphor of folding a timeline visualization into itself so as to bring similar time points close to each other. This metaphor can be applied to any dataset where a similarity metric between temporal snapshots can be defined, thus it is largely datatype-agnostic. We illustrate how time curves can visually reveal informative patterns in a range of different datasets.

  2. Evolution of Spatial Pattern of China’s Urbanization and Its Impacts on Regional Development

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Along with the remarkable economic growth,China has been experiencing a rapid urbanization in the past 60 years.However,the development of urbanization was not coordinated with regional development and the distributions of population and economy were discrete.With the method of centroid analysis,this paper demonstrates the spatial pattern of China’s urbanization and its evolution thereof from 1952 to 2005.Two indices are set up to represent the coupling states of three centroids,by which the impacts of urbanization on regional development are analyzed.In the end,from the angle of spatial pattern,this paper summarizes the characteristics of China’s urbanization,its evolution and its interaction with economic development,and then gives several suggestions on the population policy for the balanced regional development in the country.

  3. Color-pattern evolution in response to environmental stress in butterflies

    Directory of Open Access Journals (Sweden)

    Atsuki eHiyama

    2012-02-01

    Full Text Available It is generally accepted that butterfly wing color patterns have ecological and behavioral functions that evolved through natural selection. However, particular wing color patterns may physiologically be produced in response to environmental stress without significant function. These patterns would represent an extreme expression of phenotypic plasticity and can eventually be fixed genetically in a population. Here, three such cases in butterflies are concisely reviewed and their possible mechanisms of genetic assimilation are discussed. First, certain modified color pattern of Vanessa indica induced by temperature treatments resembles the natural color patterns of its closely related species of the genus Vanessa (sensu stricto. Second, a different type of color-pattern modification can be induced in Vanessa cardui as a result of a general stress response, which is very similar to the natural color pattern of its sister species Vanessa kershawi. Third, a field observation was reported, together with experimental support, to show that the color-pattern diversity of a regional population of Zizeeria maha increased at the northern range margin of this species in response to temperature stress. In these three cases, modified color patterns are unlikely to have significant functions, and these cases suggest that phenotypic plasticity plays an important role in butterfly wing color-pattern evolution. A neutral or non-functional trait can be assimilated genetically if it is linked, like a parasitic trait, with another functional trait. In addition, it is possible that environmental stress causes epigenetic modifications of genes related to color patterns and that their transgenerational inheritance facilitates the process of genetic assimilation of a neutral or non-functional trait.

  4. Colour pattern homology and evolution in Vanessa butterflies (Nymphalidae: Nymphalini): eyespot characters.

    Science.gov (United States)

    Abbasi, R; Marcus, J M

    2015-11-01

    Ocelli are serially repeated colour patterns on the wings of many butterflies. Eyespots are elaborate ocelli that function in predator avoidance and deterrence as well as in mate choice. A phylogenetic approach was used to study ocelli and eyespot evolution in Vanessa butterflies, a genus exhibiting diverse phenotypes among these serial homologs. Forty-four morphological characters based on eyespot number, arrangement, shape and the number of elements in each eyespot were defined and scored. Ocelli from eight wing cells on the dorsal and ventral surfaces of the forewing and hindwing were evaluated. The evolution of these characters was traced over a phylogeny of Vanessa based on 7750 DNA base pairs from 10 genes. Our reconstruction predicts that the ancestral Vanessa had 5 serially arranged ocelli on all four wing surfaces. The ancestral state on the dorsal forewing and ventral hindwing was ocelli arranged in two heterogeneous groups. On the dorsal hindwing, the ancestral state was either homogenous or ocelli arranged in two heterogeneous groups. On the ventral forewing, we determined that the ancestral state was organized into three heterogeneous groups. In Vanessa, almost all ocelli are individuated and capable of independent evolution relative to other colour patterns except for the ocelli in cells -1 and 0 on the dorsal and ventral forewings, which appear to be constrained to evolve in parallel. The genus Vanessa is a good model system for the study of serial homology and the interaction of selective forces with developmental architecture to produce diversity in butterfly colour patterns.

  5. Antigenic Patterns and Evolution of the Human Influenza A (H1N1) Virus.

    Science.gov (United States)

    Liu, Mi; Zhao, Xiang; Hua, Sha; Du, Xiangjun; Peng, Yousong; Li, Xiyan; Lan, Yu; Wang, Dayan; Wu, Aiping; Shu, Yuelong; Jiang, Taijiao

    2015-09-28

    The influenza A (H1N1) virus causes seasonal epidemics that result in severe illnesses and deaths almost every year. A deep understanding of the antigenic patterns and evolution of human influenza A (H1N1) virus is extremely important for its effective surveillance and prevention. Through development of antigenicity inference method for human influenza A (H1N1), named PREDAC-H1, we systematically mapped the antigenic patterns and evolution of the human influenza A (H1N1) virus. Eight dominant antigenic clusters have been inferred for seasonal H1N1 viruses since 1977, which demonstrated sequential replacements over time with a similar pattern in Asia, Europe and North America. Among them, six clusters emerged first in Asia. As for China, three of the eight antigenic clusters were detected in South China earlier than in North China, indicating the leading role of South China in H1N1 transmission. The comprehensive view of the antigenic evolution of human influenza A (H1N1) virus can help formulate better strategy for its prevention and control.

  6. Periodic Pattern of Genetic and Fitness Diversity during Evolution of an Artificial Cell-Like System.

    Science.gov (United States)

    Ichihashi, Norikazu; Aita, Takuyo; Motooka, Daisuke; Nakamura, Shota; Yomo, Tetsuya

    2015-12-01

    Genetic and phenotypic diversity are the basis of evolution. Despite their importance, however, little is known about how they change over the course of evolution. In this study, we analyzed the dynamics of the adaptive evolution of a simple evolvable artificial cell-like system using single-molecule real-time sequencing technology that reads an entire single artificial genome. We found that the genomic RNA population increases in fitness intermittently, correlating with a periodic pattern of genetic and fitness diversity produced by repeated diversification and domination. In the diversification phase, a genomic RNA population spreads within a genetic space by accumulating mutations until mutants with higher fitness are generated, resulting in an increase in fitness diversity. In the domination phase, the mutants with higher fitness dominate, decreasing both the fitness and genetic diversity. This study reveals the dynamic nature of genetic and fitness diversity during adaptive evolution and demonstrates the utility of a simplified artificial cell-like system to study evolution at an unprecedented resolution.

  7. Generic patterns in the evolution of urban water networks: Evidence from a large Asian city

    Science.gov (United States)

    Krueger, Elisabeth; Klinkhamer, Christopher; Urich, Christian; Zhan, Xianyuan; Rao, P. Suresh C.

    2017-03-01

    We examine high-resolution urban infrastructure data using every pipe for the water distribution network (WDN) and sanitary sewer network (SSN) in a large Asian city (≈4 million residents) to explore the structure as well as the spatial and temporal evolution of these infrastructure networks. Network data were spatially disaggregated into multiple subnets to examine intracity topological differences for functional zones of the WDN and SSN, and time-stamped SSN data were examined to understand network evolution over several decades as the city expanded. Graphs were generated using a dual-mapping technique (Hierarchical Intersection Continuity Negotiation), which emphasizes the functional attributes of these networks. Network graphs for WDNs and SSNs are characterized by several network topological metrics, and a double Pareto (power-law) model approximates the node-degree distributions of both water infrastructure networks (WDN and SSN), across spatial and hierarchical scales relevant to urban settings, and throughout their temporal evolution over several decades. These results indicate that generic mechanisms govern the networks' evolution, similar to those of scale-free networks found in nature. Deviations from the general topological patterns are indicative of (1) incomplete establishment of network hierarchies and functional network evolution, (2) capacity for growth (expansion) or densification (e.g., in-fill), and (3) likely network vulnerabilities. We discuss the implications of our findings for the (re-)design of urban infrastructure networks to enhance their resilience to external and internal threats.

  8. Complex and changing patterns of natural selection explain the evolution of the human hip.

    Science.gov (United States)

    Grabowski, Mark; Roseman, Charles C

    2015-08-01

    Causal explanations for the dramatic changes that occurred during the evolution of the human hip focus largely on selection for bipedal function and locomotor efficiency. These hypotheses rest on two critical assumptions. The first-that these anatomical changes served functional roles in bipedalism-has been supported in numerous analyses showing how postcranial changes likely affected locomotion. The second-that morphological changes that did play functional roles in bipedalism were the result of selection for that behavior-has not been previously explored and represents a major gap in our understanding of hominin hip evolution. Here we use evolutionary quantitative genetic models to test the hypothesis that strong directional selection on many individual aspects of morphology was responsible for the large differences observed across a sample of fossil hominin hips spanning the Plio-Pleistocene. Our approach uses covariance among traits and the differences between relatively complete fossils to estimate the net selection pressures that drove the major transitions in hominin hip evolution. Our findings show a complex and changing pattern of natural selection drove hominin hip evolution, and that many, but not all, traits hypothesized to play functional roles in bipedalism evolved as a direct result of natural selection. While the rate of evolutionary change for all transitions explored here does not exceed the amount expected if evolution was occurring solely through neutral processes, it was far above rates of evolution for morphological traits in other mammalian groups. Given that stasis is the norm in the mammalian fossil record, our results suggest that large shifts in the adaptive landscape drove hominin evolution.

  9. MtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints.

    Science.gov (United States)

    Zhidkov, Ilia; Livneh, Erez A; Rubin, Eitan; Mishmar, Dan

    2009-04-01

    Multiple human mutational landscapes of normal and cancer conditions are currently available. However, while the unique mutational patterns of tumors have been extensively studied, little attention has been paid to similarities between malignant and normal conditions. Here we compared the pattern of mutations in the mitochondrial genomes (mtDNAs) of cancer (98 sequences) and natural populations (2400 sequences). De novo mtDNA mutations in cancer preferentially colocalized with ancient variants in human phylogeny. A significant portion of the cancer mutations was organized in recurrent combinations (COMs), reaching a length of seven mutations, which also colocalized with ancient variants. Thus, by analyzing similarities rather than differences in patterns of mtDNA mutations in tumor and human evolution, we discovered evidence for similar selective constraints, suggesting a functional potential for these mutations.

  10. Refractory nonconvulsive status epilepticus in coma: analysis of the evolution of ictal patterns

    Directory of Open Access Journals (Sweden)

    Paulo Breno Noronha Liberalesso

    2012-07-01

    Full Text Available OBJECTIVE: Nonconvulsive status epilepticus (NCSE is currently considered as one of the most frequent types of status epilepticus (SE. The objective of the present study was to identify the natural history of the electrographical evolution of refractory NCSE and to establish the relationship between ictal patterns and prognosis. METHODS: We analyzed, retrospectively, 14 patients with loss of consciousness and NCSE. The ictal patterns were classified as discrete seizures (DS, merging seizures (MS, continuous ictal discharges (CID, continuous ictal discharges with flat periods (CID-F, and periodic lateralized epileptiform discharges (PLEDs. RESULTS: The ictal patterns were DS (n=7; 50.0%, PLEDs (n=3; 1.4%, CID (n=2; 14.3%, MS (n=1; 7.1%, and CID-F (n=1; 7.1%. CONCLUSIONS: NCSE electrographic findings are heterogeneous and do not follow a stereotyped sequence. PLEDs were related to a higher probability of neurological morbidity and mortality.

  11. Evolution of Eurasian teleconnection pattern and its relationship to climate anomalies in China

    Science.gov (United States)

    Wang, Ning; Zhang, Yaocun

    2015-02-01

    The Eurasian teleconnection pattern (EU) is a major mode of low-frequency variability in the Northern Hemisphere winter, with notable impacts on the temperature and precipitation anomalies in Eurasia region. To investigate the structure, life cycle and dynamical mechanisms of EU pattern, diagnostic analyses are conducted to clarify EU pattern evolution, with an emphasis on EU development and decay. In the developing stage, a geopotential height anomaly over North Atlantic emerges 6 days before EU peak phase and other three geopotential height anomalies appear one by one in the following days. During this period, all geopotential height anomalies experience considerable growth and the four-center structure of EU pattern forms 2 days before peak phase. The obvious wave train structure appears at 300 hPa. The EU pattern growth is driven by both relative vorticity advection and transient eddy fluxes. After the peak phase, the geopotential height anomaly over North Atlantic becomes weak as it decays earlier than other anomaly centers, which leads to the classic three-center structure of EU teleconnection pattern. The complete life cycle of EU pattern experience considerable growth and decay within 10 days. During the decaying stage, the horizontal divergence and the transient eddy fluxes play important roles. Additionally, the relationship of EU pattern to winter climate anomalies in China is also analyzed focusing on the decaying stage. The impact of EU pattern on temperature and precipitation in China are significant in 2-4 days after EU peak phase and the distribution of temperature and precipitation anomaly has obvious regional differences.

  12. Changes in Diversification Patterns and Signatures of Selection during the Evolution of Murinae-Associated Hantaviruses

    Directory of Open Access Journals (Sweden)

    Guillaume Castel

    2014-03-01

    Full Text Available In the last 50 years, hantaviruses have significantly affected public health worldwide, but the exact extent of the distribution of hantavirus diseases, species and lineages and the risk of their emergence into new geographic areas are still poorly known. In particular, the determinants of molecular evolution of hantaviruses circulating in different geographical areas or different host species are poorly documented. Yet, this understanding is essential for the establishment of more accurate scenarios of hantavirus emergence under different climatic and environmental constraints. In this study, we focused on Murinae-associated hantaviruses (mainly Seoul Dobrava and Hantaan virus using sequences available in GenBank and conducted several complementary phylogenetic inferences. We sought for signatures of selection and changes in patterns and rates of diversification in order to characterize hantaviruses’ molecular evolution at different geographical scales (global and local. We then investigated whether these events were localized in particular geographic areas. Our phylogenetic analyses supported the assumption that RNA virus molecular variations were under strong evolutionary constraints and revealed changes in patterns of diversification during the evolutionary history of hantaviruses. These analyses provide new knowledge on the molecular evolution of hantaviruses at different scales of time and space.

  13. Using experimental evolution to explore natural patterns between bacterial motility and resistance to bacteriophages.

    Science.gov (United States)

    Koskella, Britt; Taylor, Tiffany B; Bates, Jennifer; Buckling, Angus

    2011-11-01

    Resistance of bacteria to phages may be gained by alteration of surface proteins to which phages bind, a mechanism that is likely to be costly as these molecules typically have critical functions such as movement or nutrient uptake. To address this potential trade-off, we combine a systematic study of natural bacteria and phage populations with an experimental evolution approach. We compare motility, growth rate and susceptibility to local phages for 80 bacteria isolated from horse chestnut leaves and, contrary to expectation, find no negative association between resistance to phages and bacterial motility or growth rate. However, because correlational patterns (and their absence) are open to numerous interpretations, we test for any causal association between resistance to phages and bacterial motility using experimental evolution of a subset of bacteria in both the presence and absence of naturally associated phages. Again, we find no clear link between the acquisition of resistance and bacterial motility, suggesting that for these natural bacterial populations, phage-mediated selection is unlikely to shape bacterial motility, a key fitness trait for many bacteria in the phyllosphere. The agreement between the observed natural pattern and the experimental evolution results presented here demonstrates the power of this combined approach for testing evolutionary trade-offs.

  14. Patterns of philopatry and longevity contribute to the evolution of post-reproductive lifespan in mammals.

    Science.gov (United States)

    Nichols, H J; Zecherle, L; Arbuckle, K

    2016-02-01

    While menopause has long been known as a characteristic trait of human reproduction, evidence for post-reproductive lifespan (PRLS) has recently been found in other mammals. Adaptive and non-adaptive hypotheses have been proposed to explain the evolution of PRLS, but formal tests of these are rare. We use a phylogenetic approach to evaluate hypotheses for the evolution of PRLS among mammals. In contrast to theoretical models predicting that PRLS may be promoted by male philopatry (which increases relatedness between a female and her group in old age), we find little evidence that male philopatry led to the evolution of a post-reproductive period. However, the proportion of life spent post-reproductive was related to lifespan and patterns of philopatry, suggesting that the duration of PRLS may be impacted by both non-adaptive and adaptive processes. Finally, the proportion of females experiencing PRLS was higher in species with male philopaty and larger groups, in accordance with adaptive models of PRLS. We suggest that the origin of PRLS primarily follows the non-adaptive 'mismatch' scenario, but that patterns of philopatry may subsequently confer adaptive benefits of late-life helping.

  15. Cell state switching factors and dynamical patterning modules: complementary mediators of plasticity in development and evolution

    Indian Academy of Sciences (India)

    Stuart A Newman; Ramray Bhat; Nadejda V Mezentseva

    2009-10-01

    Ancient metazoan organisms arose from unicellular eukaryotes that had billions of years of genetic evolution behind them. The transcription factor networks present in single-celled ancestors at the origin of the Metazoa (multicellular animals) were already capable of mediating the switching of the unicellular phenotype among alternative states of gene activity in response to environmental conditions. Cell differentiation, therefore, had its roots in phenotypic plasticity, with the ancient regulatory proteins acquiring new targets over time and evolving into the ``developmental transcription factors” (DTFs) of the ``developmental-genetic toolkit.” In contrast, the emergence of pattern formation and morphogenesis in the Metazoa had a different trajectory. Aggregation of unicellular metazoan ancestors changed the organisms’ spatial scale, leading to the first ``dynamical patterning module” (DPM): cell-cell adhesion. Following this, other DPMs (defined as physical forces and processes pertinent to the scale of the aggregates mobilized by a set of toolkit gene products distinct from the DTFs), transformed simple cell aggregates into hollow, multilayered, segmented, differentiated and additional complex structures, with minimal evolution of constituent genes. Like cell differentiation, therefore, metazoan morphologies also originated from plastic responses of cells and tissues. Here we describe examples of DTFs and most of the important DPMs, discussing their complementary roles in the evolution of developmental mechanisms. We also provide recently characterized examples of DTFs in cell type switching and DPMs in morphogenesis of avian limb bud mesenchyme, an embryo-derived tissue that retains a high degree of developmental plasticity.

  16. Distinctive patterns of evolution of the δ-globin gene (HBD in primates.

    Directory of Open Access Journals (Sweden)

    Ana Moleirinho

    Full Text Available In most vertebrates, hemoglobin (Hb is a heterotetramer composed of two dissimilar globin chains, which change during development according to the patterns of expression of α- and β-globin family members. In placental mammals, the β-globin cluster includes three early-expressed genes, ε(HBE-γ(HBG-ψβ(HBBP1, and the late expressed genes, δ (HBD and β (HBB. While HBB encodes the major adult β-globin chain, HBD is weakly expressed or totally silent. Paradoxically, in human populations HBD shows high levels of conservation typical of genes under strong evolutionary constraints, possibly due to a regulatory role in the fetal-to-adult switch unique of Anthropoid primates. In this study, we have performed a comprehensive phylogenetic and comparative analysis of the two adult β-like globin genes in a set of diverse mammalian taxa, focusing on the evolution and functional divergence of HBD in primates. Our analysis revealed that anthropoids are an exception to a general pattern of concerted evolution in placental mammals, showing a high level of sequence conservation at HBD, less frequent and shorter gene conversion events. Moreover, this lineage is unique in the retention of a functional GATA-1 motif, known to be involved in the control of the developmental expression of the β-like globin genes. We further show that not only the mode but also the rate of evolution of the δ-globin gene in higher primates are strictly associated with the fetal/adult β-cluster developmental switch. To gain further insight into the possible functional constraints that have been shaping the evolutionary history of HBD in primates, we calculated dN/dS (ω ratios under alternative models of gene evolution. Although our results indicate that HBD might have experienced different selective pressures throughout primate evolution, as shown by different ω values between apes and Old World Monkeys + New World Monkeys (0.06 versus 0.43, respectively, these estimates

  17. Evolution of the insect terminal patterning system--insights from the milkweed bug, Oncopeltus fasciatus.

    Science.gov (United States)

    Weisbrod, Anat; Cohen, Mira; Chipman, Ariel D

    2013-08-01

    The anterior and posterior ends of the insect embryo are patterned through the terminal patterning system, which is best known from the fruitfly Drosophila melanogaster. In Drosophila, the RTK receptor Torso and its presumed co-activator Torso-like initiate a signaling cascade, which activates two terminal gap genes, tailless and huckebein. These in turn interact with various patterning genes to define terminal structures. Work on other insect species has shown that this system is poorly conserved, and not all of its components have been found in all cases studied. We place the variability of the system within a broader phylogenetic framework. We describe the expression and knock-down phenotypes of the homologues of terminal patterning genes in the hemimetabolous Oncopeltus fasciatus. We have examined the interactions among these genes and between them and other patterning genes. We demonstrate that all of these genes have different roles in Oncopeltus relative to Drosophila; torso-like is expressed in follicle cells during oogenesis and is involved in the invagination of the blastoderm to form the germ band, and possibly also in defining the growth zone; tailless is regulated by orthodenticle and has a role only in anterior determination; huckebein is expressed only in the middle of the blastoderm; finally, torso was not found in Oncopeltus and its role in terminal patterning seems novel within holometabolous insects. We then use our data, together with published data on other insects, to reconstruct the evolution of the terminal patterning gene network in insects. We suggest that the Drosophila terminal patterning network evolved recently in the lineage leading to the Diptera, and represents an example of evolutionary "tinkering", where pre-existing pathways are co-opted for a new function.

  18. Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity.

    Directory of Open Access Journals (Sweden)

    Katja Pfafferott

    Full Text Available Cellular immune responses during acute Hepatitis C virus (HCV and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s within CD8+ T-cell epitopes allows these viruses to subvert host immune control. This study examined HCV evolution in 21 HCV genotype 1-infected subjects to characterise the level of viral adaptation during acute and early HCV infection. Of the total mutations observed 25% were within described CD8+ T-cell epitopes or at viral adaptation sites. Most mutations were maintained into the chronic phase of HCV infection (75%. The lack of reversion of adaptations and high proportion of silent substitutions suggests that HCV has structural and functional limitations that constrain evolution. These results were compared to the pattern of viral evolution observed in 98 subjects during a similar phase in HIV infection from a previous study. In contrast to HCV, evolution during acute HIV infection is marked by high levels of amino acid change relative to silent substitutions, including a higher proportion of adaptations, likely reflecting strong and continued CD8+ T-cell pressure combined with greater plasticity of the virus. Understanding viral escape dynamics for these two viruses is important for effective T cell vaccine design.

  19. HypGrid2D. A 2-d mesh generator

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, N.N.

    1998-03-01

    The implementation of a hyperbolic mesh generation procedure, based on an equation for orthogonality and an equation for the cell face area is described. The method is fast, robust and gives meshes with good smoothness and orthogonality. The procedure is implemented in a program called HypGrid2D. The HypGrid2D program is capable of generating C-, O- and `H`-meshes for use in connection with the EllipSys2D Navier-Stokes solver. To illustrate the capabilities of the program, some test examples are shown. First a series of C-meshes are generated around a NACA-0012 airfoil. Secondly a series of O-meshes are generated around a NACA-65-418 airfoil. Finally `H`-meshes are generated over a Gaussian hill and a linear escarpment. (au)

  20. The achaete-scute complex in Diptera: patterns of noncoding sequence evolution.

    Science.gov (United States)

    Negre, B; Simpson, P

    2015-10-01

    The achaete-scute complex (AS-C) has been a useful paradigm for the study of pattern formation and its evolution. achaete-scute genes have duplicated and evolved distinct expression patterns during the evolution of cyclorraphous Diptera. Are the expression patterns in different species driven by conserved regulatory elements? If so, when did such regulatory elements arise? Here, we have sequenced most of the AS-C of the fly Calliphora vicina (including the genes achaete, scute and lethal of scute) to compare noncoding sequences with known cis-regulatory sequences in Drosophila. The organization of the complex is conserved with respect to Drosophila species. There are numerous small stretches of conserved noncoding sequence that, in spite of high sequence turnover, display binding sites for known transcription factors. Synteny of the blocks of conserved noncoding sequences is maintained suggesting not only conservation of the position of regulatory elements but also an origin prior to the divergence between these two species. We propose that some of these enhancers originated by duplication with their target genes.

  1. Evolution-development congruence in pattern formation dynamics: Bifurcations in gene expression and regulation of networks structures.

    Science.gov (United States)

    Kohsokabe, Takahiro; Kaneko, Kunihiko

    2016-01-01

    Search for possible relationships between phylogeny and ontogeny is important in evolutionary-developmental biology. Here we uncover such relationships by numerical evolution and unveil their origin in terms of dynamical systems theory. By representing developmental dynamics of spatially located cells with gene expression dynamics with cell-to-cell interaction under external morphogen gradient, gene regulation networks are evolved under mutation and selection with the fitness to approach a prescribed spatial pattern of expressed genes. For most numerical evolution experiments, evolution of pattern over generations and development of pattern by an evolved network exhibit remarkable congruence. Both in the evolution and development pattern changes consist of several epochs where stripes are formed in a short time, while for other temporal regimes, pattern hardly changes. In evolution, these quasi-stationary regimes are generations needed to hit relevant mutations, while in development, they are due to some gene expression that varies slowly and controls the pattern change. The morphogenesis is regulated by combinations of feedback or feedforward regulations, where the upstream feedforward network reads the external morphogen gradient, and generates a pattern used as a boundary condition for the later patterns. The ordering from up to downstream is common in evolution and development, while the successive epochal changes in development and evolution are represented as common bifurcations in dynamical-systems theory, which lead to the evolution-development congruence. Mechanism of exceptional violation of the congruence is also unveiled. Our results provide a new look on developmental stages, punctuated equilibrium, developmental bottlenecks, and evolutionary acquisition of novelty in morphogenesis.

  2. Spatial pattern of reference evapotranspiration change and its temporal evolution over Southwest China

    Science.gov (United States)

    Sun, Shanlei; Wang, Guojie; Huang, Jin; Mu, Mengyuan; Yan, Guixia; Liu, Chunwei; Gao, Chujie; Li, Xing; Yin, Yixing; Zhang, Fangmin; Zhu, Siguang; Hua, Wenjian

    2016-09-01

    Due to the close relationship of climate change with reference evapotranspiration (ETo), detecting changes in ETo spatial distribution and its temporal evolution at local and regional levels is favorable to comprehensively understand climate change-induced impacts on hydrology and agriculture. In this study, the objective is to identify whether climate change has caused variation of ETo spatial distribution in different analysis periods [i.e., long- (20-year), medium- (10-year), and short-term (5-year)] and to investigate its temporal evolution (namely, when these changes happened) at annual and monthly scales in Southwest China (SWC). First, we estimated ETo values using the United Nations Food and Agriculture Organization (FAO) Penman-Monteith equation, based on historical climate data measured at 269 weather sites during 1973-2012. The analysis of variance (ANOVA) results indicated that the spatial pattern of annual ETo had significantly changed during the past 40 years, particularly in west SWC for the long-term analysis period, and west and southeast SWC in both medium- and short-term periods, which corresponded to the percent area of significant differences which were 21.9, 58.0, and 48.2 %, respectively. For investigating temporal evolution of spatial patterns of annual ETo, Duncan's multiple range test was used, and we found that the most significant changes appeared during 1988-2002 with the significant area of higher than 25.0 %. In addition, for long-, medium-, and short-term analysis periods, the spatial distribution has significantly changed during March, September, November, and December, especially in the corresponding periods of 1988-1997, 1983-1992, 1973-1977, and 1988-2002. All in all, climate change has resulted in significant ETo changes in SWC since the 1970s. Knowledge of climate change-induced spatial distribution of ETo and its temporal evolution would aid in formulating strategies for water resources and agricultural managements.

  3. Uncoupling of complex regulatory patterning during evolution of larval development in echinoderms

    Directory of Open Access Journals (Sweden)

    Jennings Charlotte K

    2010-11-01

    Full Text Available Abstract Background Conservation of orthologous regulatory gene expression domains, especially along the neuroectodermal anterior-posterior axis, in animals as disparate as flies and vertebrates suggests that common patterning mechanisms have been conserved since the base of Bilateria. The homology of axial patterning is far less clear for the many marine animals that undergo a radical transformation in body plan during metamorphosis. The embryos of these animals are microscopic, feeding within the plankton until they metamorphose into their adult forms. Results We describe here the localization of 14 transcription factors within the ectoderm during early embryogenesis in Patiria miniata, a sea star with an indirectly developing planktonic bipinnaria larva. We find that the animal-vegetal axis of this very simple embryo is surprisingly well patterned. Furthermore, the patterning that we observe throughout the ectoderm generally corresponds to that of "head/anterior brain" patterning known for hemichordates and vertebrates, which share a common ancestor with the sea star. While we suggest here that aspects of head/anterior brain patterning are generally conserved, we show that another suite of genes involved in retinal determination is absent from the ectoderm of these echinoderms and instead operates within the mesoderm. Conclusions Our findings therefore extend, for the first time, evidence of a conserved axial pattering to echinoderm embryos exhibiting maximal indirect development. The dissociation of head/anterior brain patterning from "retinal specification" in echinoderm blastulae might reflect modular changes to a developmental gene regulatory network within the ectoderm that facilitates the evolution of these microscopic larvae.

  4. Unique expression patterns of multiple key genes associated with the evolution of mammalian flight

    OpenAIRE

    2014-01-01

    Bats are the only mammals capable of true flight. Critical adaptations for flight include a pair of dramatically elongated hands with broad wing membranes. To study the molecular mechanisms of bat wing evolution, we perform genomewide mRNA sequencing and in situ hybridization for embryonic bat limbs. We identify seven key genes that display unique expression patterns in embryonic bat wings and feet, compared with mouse fore- and hindlimbs. The expression of all 5′HoxD genes (Hoxd9–13) and Tbx...

  5. TPR repeats and ELTR pattern: length variation as a function evolution mechanism.

    Science.gov (United States)

    Yang, Ke-Qian

    2007-12-01

    TPR repeat was originally defined as a 34 amino acid structural repeat (TPR-34). Equal length tandem repeats (ELTR) was proposed to represent the ancestral repeat pattern. Length polymorphism of TPR repeats was analyzed using PATTINPROT, two new versions of TPR repeat of 40 and 42 amino acids were identified. These 'long' TPRs endow new functional capacities to the resulting proteins. A strong correlation between varied lengths and new functions supports the hypothesis that length variation is an underlying mechanism for the function evolution of repeat containing proteins.

  6. Lineage tracing of the bivalve shell field with special interest in the descendants of the 2d blastomere.

    Science.gov (United States)

    Mohri, Masakuni; Hashimoto, Naoki; Wada, Hiroshi

    2016-03-01

    By evolving bilaterally separated shell plates, bivalves acquired a unique body plan in which their soft tissues are completely protected by hard shell plates. In this unique body plan, mobility between the separated shell plates is provided by novel structures such as a ligament and adductor muscles. As a first step towards understanding how the bivalve body plan was established, we investigated the development of the separated shell plates and ligament. Over 100 years ago, it was hypothesized that the development of separated shell plates is tightly linked with the unique cell cleavage (division) pattern of bivalves during development, wherein each bilateral daughter cell of the 2d descendant 2d(1121) develops into one of the bilateral shell fields. In this study, we tested this hypothesis by tracing the cell lineages of the Japanese purple mussel Septifer virgatus. Although the shell fields were found to be exclusively derived from the bilateral descendant cells of 2d: 2d(11211) and 2d(11212), the descendants of these cells were not restricted to shell fields alone, nor were they confined to the left or right side of the shell field based on their lineage. Our study demonstrated that ligament cells are also derived from 2d(11211) and 2d(11212), indicating that the ligament cells emerged as a subpopulation of shell field cells. This also suggests that the establishment of the novel developmental system for the ligament cells was critical for the evolution of the unique body plan of bivalves.

  7. The Repeat Pattern Toolkit (RPT): Analyzing the structure and evolution of the C. elegans genome

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, P.; States, D.J. [Washington Univ., St. Louis, MO (United States)

    1994-12-31

    Over 3.6 million bases of DNA sequence from chromosome III of the C. elegans have been determined. The availability of this extended region of contiguous sequence has allowed us to analyze the nature and prevalence of repetitive sequences in the genome of a eukaryotic organism with a high gene density. We have assembled a Repeat Pattern Toolkit (RPT) to analyze the patterns of repeats occurring in DNA. The tools include identifying significant local alignments (utilizing both two-way and three-way alignments), dividing the set of alignments into connected components (signifying repeat families), computing evolutionary distance between repeat family members, constructing minimum spanning trees from the connected components, and visualizing the evolution of the repeat families. Over 7000 families of repetitive sequences were identified. The size of the families ranged from isolated pairs to over 1600 segments of similar sequence. Approximately 12.3% of the analyzed sequence participates in a repeat element.

  8. Quasiparticle interference in unconventional 2D systems

    Science.gov (United States)

    Chen, Lan; Cheng, Peng; Wu, Kehui

    2017-03-01

    At present, research of 2D systems mainly focuses on two kinds of materials: graphene-like materials and transition-metal dichalcogenides (TMDs). Both of them host unconventional 2D electronic properties: pseudospin and the associated chirality of electrons in graphene-like materials, and spin-valley-coupled electronic structures in the TMDs. These exotic electronic properties have attracted tremendous interest for possible applications in nanodevices in the future. Investigation on the quasiparticle interference (QPI) in 2D systems is an effective way to uncover these properties. In this review, we will begin with a brief introduction to 2D systems, including their atomic structures and electronic bands. Then, we will discuss the formation of Friedel oscillation due to QPI in constant energy contours of electron bands, and show the basic concept of Fourier-transform scanning tunneling microscopy/spectroscopy (FT-STM/STS), which can resolve Friedel oscillation patterns in real space and consequently obtain the QPI patterns in reciprocal space. In the next two parts, we will summarize some pivotal results in the investigation of QPI in graphene and silicene, in which systems the low-energy quasiparticles are described by the massless Dirac equation. The FT-STM experiments show there are two different interference channels (intervalley and intravalley scattering) and backscattering suppression, which associate with the Dirac cones and the chirality of quasiparticles. The monolayer and bilayer graphene on different substrates (SiC and metal surfaces), and the monolayer and multilayer silicene on a Ag(1 1 1) surface will be addressed. The fifth part will introduce the FT-STM research on QPI in TMDs (monolayer and bilayer of WSe2), which allow us to infer the spin texture of both conduction and valence bands, and present spin-valley coupling by tracking allowed and forbidden scattering channels.

  9. Numerical study of IP3-induced Ca2+ spiral pattern evolution

    Institute of Scientific and Technical Information of China (English)

    Tang Jun; Ma Jun; Yi Ming; Jia Ya

    2008-01-01

    The effect of change in concentration of messenger molecule inositol 1,4,5-trisphosphate (IP3) on intracellular Ca2+spiral pattern evolution is studied numerically.The results indicate that when the IP3 concentration decreases from 0.27μM,a physiologically reasonable value,to different values,the spiral centre drifts to the edge of the medium and disappears for a small enough IP3 concentration.The instability of spiral pattern can be understood in terms of excitability-change controlled by the IP3 concentration.On the other hand,when the IP3 concentration increases from 0.27μM,a homogeneous area with a high Ca2+ concentration emerges and competes with the spiral pattern.A high enough IP3 concentration can lead the homogeneous area to occupy the whole medium.The instability of spiral pattern is ascribed to the change in stability of a stationary state with a high Ca2+ concentration.

  10. ChIP-Seq-Annotated Heliconius erato Genome Highlights Patterns of cis-Regulatory Evolution in Lepidoptera.

    Science.gov (United States)

    Lewis, James J; van der Burg, Karin R L; Mazo-Vargas, Anyi; Reed, Robert D

    2016-09-13

    Uncovering phylogenetic patterns of cis-regulatory evolution remains a fundamental goal for evolutionary and developmental biology. Here, we characterize the evolution of regulatory loci in butterflies and moths using chromatin immunoprecipitation sequencing (ChIP-seq) annotation of regulatory elements across three stages of head development. In the process we provide a high-quality, functionally annotated genome assembly for the butterfly, Heliconius erato. Comparing cis-regulatory element conservation across six lepidopteran genomes, we find that regulatory sequences evolve at a pace similar to that of protein-coding regions. We also observe that elements active at multiple developmental stages are markedly more conserved than elements with stage-specific activity. Surprisingly, we also find that stage-specific proximal and distal regulatory elements evolve at nearly identical rates. Our study provides a benchmark for genome-wide patterns of regulatory element evolution in insects, and it shows that developmental timing of activity strongly predicts patterns of regulatory sequence evolution.

  11. Unique expression patterns of multiple key genes associated with the evolution of mammalian flight.

    Science.gov (United States)

    Wang, Zhe; Dai, Mengyao; Wang, Yao; Cooper, Kimberly L; Zhu, Tengteng; Dong, Dong; Zhang, Junpeng; Zhang, Shuyi

    2014-05-22

    Bats are the only mammals capable of true flight. Critical adaptations for flight include a pair of dramatically elongated hands with broad wing membranes. To study the molecular mechanisms of bat wing evolution, we perform genomewide mRNA sequencing and in situ hybridization for embryonic bat limbs. We identify seven key genes that display unique expression patterns in embryonic bat wings and feet, compared with mouse fore- and hindlimbs. The expression of all 5'HoxD genes (Hoxd9-13) and Tbx3, six known crucial transcription factors for limb and digit development, is extremely high and prolonged in the elongating wing area. The expression of Fam5c, a tumour suppressor, in bat limbs is bat-specific and significantly high in all short digit regions (the thumb and foot digits). These results suggest multiple genetic changes occurred independently during the evolution of bat wings to elongate the hand digits, promote membrane growth and keep other digits short. Our findings also indicate that the evolution of limb morphology depends on the complex integration of multiple gene regulatory networks and biological processes that control digit formation and identity, chondrogenesis, and interdigital regression or retention.

  12. Convergence and divergence in the evolution of cat skulls: temporal and spatial patterns of morphological diversity.

    Directory of Open Access Journals (Sweden)

    Manabu Sakamoto

    Full Text Available BACKGROUND: Studies of biological shape evolution are greatly enhanced when framed in a phylogenetic perspective. Inclusion of fossils amplifies the scope of macroevolutionary research, offers a deep-time perspective on tempo and mode of radiations, and elucidates life-trait changes. We explore the evolution of skull shape in felids (cats through morphometric analyses of linear variables, phylogenetic comparative methods, and a new cladistic study of saber-toothed cats. METHODOLOGY/PRINCIPAL FINDINGS: A new phylogenetic analysis supports the monophyly of saber-toothed cats (Machairodontinae exclusive of Felinae and some basal felids, but does not support the monophyly of various saber-toothed tribes and genera. We quantified skull shape variation in 34 extant and 18 extinct species using size-adjusted linear variables. These distinguish taxonomic group membership with high accuracy. Patterns of morphospace occupation are consistent with previous analyses, for example, in showing a size gradient along the primary axis of shape variation and a separation between large and small-medium cats. By combining the new phylogeny with a molecular tree of extant Felinae, we built a chronophylomorphospace (a phylogeny superimposed onto a two-dimensional morphospace through time. The evolutionary history of cats was characterized by two major episodes of morphological divergence, one marking the separation between saber-toothed and modern cats, the other marking the split between large and small-medium cats. CONCLUSIONS/SIGNIFICANCE: Ancestors of large cats in the 'Panthera' lineage tend to occupy, at a much later stage, morphospace regions previously occupied by saber-toothed cats. The latter radiated out into new morphospace regions peripheral to those of extant large cats. The separation between large and small-medium cats was marked by considerable morphologically divergent trajectories early in feline evolution. A chronophylomorphospace has wider

  13. Phylogenetic patterns and the adaptive evolution of osmoregulation in fiddler crabs (Brachyura, Uca)

    Science.gov (United States)

    Faria, Samuel Coelho; Provete, Diogo Borges; Thurman, Carl Leo

    2017-01-01

    Salinity is the primary driver of osmoregulatory evolution in decapods, and may have influenced their diversification into different osmotic niches. In semi-terrestrial crabs, hyper-osmoregulatory ability favors sojourns into burrows and dilute media, and provides a safeguard against hemolymph dilution; hypo-osmoregulatory ability underlies emersion capability and a life more removed from water sources. However, most comparative studies have neglected the roles of the phylogenetic and environmental components of inter-specific physiological variation, hindering evaluation of phylogenetic patterns and the adaptive nature of osmoregulatory evolution. Semi-terrestrial fiddler crabs (Uca) inhabit fresh to hyper-saline waters, with species from the Americas occupying higher intertidal habitats than Indo-west Pacific species mainly found in the low intertidal zone. Here, we characterize numerous osmoregulatory traits in all ten fiddler crabs found along the Atlantic coast of Brazil, and we employ phylogenetic comparative methods using 24 species to test for: (i) similarities of osmoregulatory ability among closely related species; (ii) salinity as a driver of osmoregulatory evolution; (iii) correlation between salt uptake and secretion; and (iv) adaptive peaks in osmoregulatory ability in the high intertidal American lineages. Our findings reveal that osmoregulation in Uca exhibits strong phylogenetic patterns in salt uptake traits. Salinity does not correlate with hyper/hypo-regulatory abilities, but drives hemolymph osmolality at ambient salinities. Osmoregulatory traits have evolved towards three adaptive peaks, revealing a significant contribution of hyper/hypo-regulatory ability in the American clades. Thus, during the evolutionary history of fiddler crabs, salinity has driven some of the osmoregulatory transformations that underpin habitat diversification, although others are apparently constrained phylogenetically. PMID:28182764

  14. DESIGN METHODOLOGY OF NETWORKED SOFTWARE EVOLUTION GROWTH BASED ON SOFTWARE PATTERNS

    Institute of Scientific and Technical Information of China (English)

    Keqing HE; Rong PENG; Jing LIU; Fei HE; Peng LIANG; Bing LI

    2006-01-01

    Recently, some new characteristics of complex networks attract the attentions of scientists in different fields, and lead to many kinds of emerging research directions. So far, most of the research work has been limited in discovery of complex network characteristics by structure analysis in large-scale software systems. This paper presents the theoretical basis, design method, algorithms and experiment results of the research. It firstly emphasizes the significance of design method of evolution growth for network topology of Object Oriented (OO) software systems, and argues that the selection and modulation of network models with various topology characteristics will bring un-ignorable effect on the process of design and implementation of OO software systems. Then we analyze the similar discipline of "negation of negation and compromise" between the evolution of network models with different topology characteristics and the development of software modelling methods. According to the analysis of the growth features of software patterns, we propose an object-oriented software network evolution growth method and its algorithms in succession. In addition, we also propose the parameter systems for Oosoftware system metrics based on complex network theory. Based on these parameter systems, it can analyze the features of various nodes, links and local-world, modulate the network topology and guide the software metrics. All these can be helpful to the detailed design, implementation and performance analysis. Finally, we focus on the application of the evolution algorithms and demonstrate it by a case study.Comparing the results from our early experiments with methodologies in empirical software engineering, we believe that the proposed software engineering design method is a computational software engineering approach based on complex network theory. We argue that this method should be greatly beneficial for the design, implementation, modulation and metrics of

  15. Wing pattern evolution and the origins of mimicry among North American admiral butterflies (Nymphalidae: Limenitis).

    Science.gov (United States)

    Mullen, Sean P

    2006-06-01

    The evolution of wing pattern diversity in butterflies has emerged as a model system for understanding the origins and maintenance of adaptive phenotypic novelty. Admiral butterflies (genus Limenitis) are an attractive system for studying wing pattern diversity because mimicry is common among the North American species and hybrid zones occur wherever mimetic and non-mimetic wing pattern races meet. However, the utility of this system has been limited because the evolutionary relationships among these butterflies remain unclear. Here I present a robust species-level phylogeny of Limenitis based on 1911 bp of two mitochondrial genes (COI and COII) and 904 bp of EF1-alpha for all five of the Nearctic species/wing pattern races, the majority of the Palearctic species, and three outgroup genera; Athyma, Moduza (Limenitidini), and Neptis (Limenitidinae: Neptini). Maximum-likelihood and Bayesian analyses indicate that the North American species are a well-supported, monophyletic lineage that is most closely related to the widespread, Palearctic, Poplar admiral (L. populi). Within North America, the Viceroy (L. archippus) is the basal lineage while the relationships among the remaining species are not well resolved. A combined maximum-likelihood analysis, however, indicates that the two western North America species (L. lorquini and L. weidemeyerii) are sister taxa and closely related to the wing pattern subspecies of the polytypic Limenitis arthemis species complex. These results are consistent with (1) an ancestral host-shift to Salicaceae by the common ancestor of the Poplar admiral and the Nearctic admiral lineage, (2) a single colonization of the Nearctic, and (3) a subsequent radiation of the North American forms leading to at least three independent origins of mimicry.

  16. Patterns of evolution of MHC class II genes of crows (Corvus suggest trans-species polymorphism

    Directory of Open Access Journals (Sweden)

    John A. Eimes

    2015-03-01

    Full Text Available A distinguishing characteristic of genes that code for the major histocompatibility complex (MHC is that alleles often share more similarity between, rather than within species. There are two likely mechanisms that can explain this pattern: convergent evolution and trans-species polymorphism (TSP, in which ancient allelic lineages are maintained by balancing selection and retained by descendant species. Distinguishing between these two mechanisms has major implications in how we view adaptation of immune genes. In this study we analyzed exon 2 of the MHC class IIB in three passerine bird species in the genus Corvus: jungle crows (Corvus macrorhynchos japonensis American crows (C. brachyrhynchos and carrion crows (C. corone orientalis. Carrion crows and American crows are recently diverged, but allopatric, sister species, whereas carrion crows and jungle crows are more distantly related but sympatric species, and possibly share pathogens linked to MHC IIB polymorphisms. These patterns of evolutionary divergence and current geographic ranges enabled us to test for trans-species polymorphism and convergent evolution of the MHC IIB in crows. Phylogenetic reconstructions of MHC IIB sequences revealed several well supported interspecific clusters containing all three species, and there was no biased clustering of variants among the sympatric carrion crows and jungle crows. The topologies of phylogenetic trees constructed from putatively selected sites were remarkably different than those constructed from putatively neutral sites. In addition, trees constructed using non-synonymous substitutions from a continuous fragment of exon 2 had more, and generally more inclusive, supported interspecific MHC IIB variant clusters than those constructed from the same fragment using synonymous substitutions. These phylogenetic patterns suggest that recombination, especially gene conversion, has partially erased the signal of allelic ancestry in these species. While

  17. Flow pattern and lift evolution of hydrofoil with control of electro-magnetic forces

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The initial responses and evolutions of the flow pattern and lift coefficient of a hydrofoil under the action of electro-magnetic (Lorentz) force have been studied experimentally and numerically, and trace particle methods are employed for them. With the introduction of BVF (boundary vortex flux), the quantitative relation among Lorentz forces, BVF and lifts is deduced. The influences of flow patterns on the hydrofoil lift coefficient have been discussed based on the BVF distribution, and the flow control mechanism of Lorentz force for a hydrofoil has been elucidated. Our results show that the flow pattern and lift of the hydrofoil vary periodically without any force. However, with the action of streamwise Lorentz forces, the separation point on the hydrofoil surface moves backward with a certain velocity, which makes the flow field steady finally. The streamwise Lorentz force raises the foil lift due to the increase of BVF intensity. On the other hand, Lorentz force also increases the hydrofoil surface pressure, which makes the lift decrease. However, the factor leading to the lift enhancement is determinant, therefore, the Lorentz force on the suction side can increase the lift, and the stronger the Lorentz force, the larger the lift enhancement. Our results also show that the localized Lorentz force can also both suppress the flow separation and increase the hydrofoil lift coefficient, furthermore, the Lorentz force located on the tail acts better than that located on the front.

  18. Patterns of evolution and host gene mimicry in influenza and other RNA viruses.

    Directory of Open Access Journals (Sweden)

    Benjamin D Greenbaum

    2008-06-01

    Full Text Available It is well known that the dinucleotide CpG is under-represented in the genomic DNA of many vertebrates. This is commonly thought to be due to the methylation of cytosine residues in this dinucleotide and the corresponding high rate of deamination of 5-methycytosine, which lowers the frequency of this dinucleotide in DNA. Surprisingly, many single-stranded RNA viruses that replicate in these vertebrate hosts also have a very low presence of CpG dinucleotides in their genomes. Viruses are obligate intracellular parasites and the evolution of a virus is inexorably linked to the nature and fate of its host. One therefore expects that virus and host genomes should have common features. In this work, we compare evolutionary patterns in the genomes of ssRNA viruses and their hosts. In particular, we have analyzed dinucleotide patterns and found that the same patterns are pervasively over- or under-represented in many RNA viruses and their hosts suggesting that many RNA viruses evolve by mimicking some of the features of their host's genes (DNA and likely also their corresponding mRNAs. When a virus crosses a species barrier into a different host, the pressure to replicate, survive and adapt, leaves a footprint in dinucleotide frequencies. For instance, since human genes seem to be under higher pressure to eliminate CpG dinucleotide motifs than avian genes, this pressure might be reflected in the genomes of human viruses (DNA and RNA viruses when compared to those of the same viruses replicating in avian hosts. To test this idea we have analyzed the evolution of the influenza virus since 1918. We find that the influenza A virus, which originated from an avian reservoir and has been replicating in humans over many generations, evolves in a direction strongly selected to reduce the frequency of CpG dinucleotides in its genome. Consistent with this observation, we find that the influenza B virus, which has spent much more time in the human population, has

  19. Aero Fighter - 2D Gaming

    CERN Document Server

    Ahmed, Zeeshan

    2010-01-01

    Designing and developing quality based computer game is always a challenging task for developers. In this paper I briefly discuss aero fighting war game based on simple 2D gaming concepts and developed in C & C++ programming languages, using old bitmapping concepts. Going into the details of the game development, I discuss the designed strategies, flow of game and implemented prototype version of game, especially for beginners of game programming.

  20. Identification of Tumor Evolution Patterns by Means of Inductive Logic Programming

    Institute of Scientific and Technical Information of China (English)

    Vitoantonio Bevilacqua; Patrizia Chiarappa; Giuseppe Mastronardi; Filippo Menolascina; Angelo Paradiso; Stefania Tommasi

    2008-01-01

    In considering key events of genomic disorders in the development and progression of cancer, the correlation between genomic instability and carcinogenesis is currently under investigation. In this work, we propose an inductive logic programming approach to the problem of modeling evolution patterns for breast cancer. Using this approach, it is possible to extract fingerprints of stages of the disease that can be used in order to develop and deliver the most adequate therapies to patients. Furthermore, such a model can help physicians and biologists in the elucidation of molecular dynamics underlying the aberrations-waterfall model behind carcinogenesis. By showing results obtained on a real-world dataset, we try to give some hints about further approach to the knowledge-driven validations of such hypotheses.

  1. Distinct patterns in the regulation and evolution of human cancer genes.

    Science.gov (United States)

    Furney, Simon J; Madden, Stephen F; Kisiel, Tomasz A; Higgins, Desmond G; Lopez-Bigas, Nuria

    2008-01-01

    Understanding the mechanism of regulation of cancer genes and the constraints on their coding sequences is of fundamental importance in understanding the process of tumour development. Here we test the hypothesis that tumour suppressor genes and proto-oncogenes, due to their involvement in tumourigenesis, have distinct patterns of regulation and coding selective constraints compared to non-cancer genes. Indeed, we found significantly greater conservation in the promoter regions of proto-oncogenes, suggesting that these genes are more tightly regulated, i.e. they are more likely to contain a higher density of cis-regulatory elements. Furthermore, proto-oncogenes appear to be preferentially targeted by microRNAs and have longer 3' UTRs. In addition, proto-oncogene evolution appears to be highly constrained, compared to tumour suppressor genes and non-cancer genes. A number of these trends are confirmed in breast and colon cancer gene sets recently identified by mutational screening.

  2. Inferring directions of evolution from patterns of variation: the legacy of Sergei Meyen.

    Science.gov (United States)

    Sharov, Alexei A; Igamberdiev, Abir U

    2014-09-01

    In the era of the extended evolutionary synthesis, which no longer considers natural selection as the only leading factor of evolution, it is meaningful to revisit the legacy of biologists who discussed the role of alternative factors. Here we analyze the evolutionary views of Sergei Meyen (1935-1987), a paleobotanist who argued that the theory of evolution should incorporate a "nomothetical" approach which infers the laws of morphogenesis (i.e., form generation) from the observed patterns of variation in living organisms and in the fossil records. Meyen developed a theory of "repeated polymorphic sets" (RPSs), which he applied consistently to describe inter-organism variation in populations, intra-organism variation of metameric organs, variation of abnormalities, heterotopy, changes during embryo development, and inter-species variation within evolutionary lineages. The notion of RPS assumes the active nature of organisms that possess hidden morphogenic and behavioral capacities. Meyen's theory is compatible with Darwin's natural selection; however, Meyen emphasized the importance of other forms of selection (e.g., selection of developmental trajectories, habitats, and behaviors) in choosing specific elements from the RPS. Finally, Meyen developed a new typological concept of time, where time represents variability (i.e., change) of real objects such as living organisms or geological formations.

  3. Inferring directions of evolution from patterns of variation: The legacy of Sergei Meyen

    Science.gov (United States)

    Sharov, Alexei A.; Igamberdiev, Abir U.

    2014-01-01

    In the era of the Extended Evolutionary Synthesis, which no longer considers natural selection as the only leading factor of evolution, it is meaningful to revisit the legacy of biologists who discussed the role of alternative factors. Here we analyze the evolutionary views of Sergei Meyen (1935-1987), a paleobotanist who argued that the theory of evolution should incorporate a “nomothetical” approach which infers the laws of morphogenesis (i.e., form generation) from the observed patterns of variation in living organisms and in the fossil records. Meyen developed a theory of “repeated polymorphic sets” (RPSs), which he applied consistently to describe inter-organism variation in populations, intra-organism variation of metameric organs, variation of abnormalities, heterotopy, changes during embryo development, and inter-species variation within evolutionary lineages. The notion of RPS assumes the active nature of organisms that possess hidden morphogenic and behavioural capacities. Meyen's theory is compatible with Darwin's natural selection; however Meyen emphasized the importance of other forms of selection (e.g., selection of developmental trajectories, habitats, and behaviours) in choosing specific elements from the RPS. Finally, Meyen developed a new typological concept of time, where time represents variability (i.e., change) of real objects such as living organisms or geological formations. PMID:25072709

  4. Amphioxus and lamprey AP-2 genes: implications for neural crest evolution and migration patterns

    Science.gov (United States)

    Meulemans, Daniel; Bronner-Fraser, Marianne

    2002-01-01

    The neural crest is a uniquely vertebrate cell type present in the most basal vertebrates, but not in cephalochordates. We have studied differences in regulation of the neural crest marker AP-2 across two evolutionary transitions: invertebrate to vertebrate, and agnathan to gnathostome. Isolation and comparison of amphioxus, lamprey and axolotl AP-2 reveals its extensive expansion in the vertebrate dorsal neural tube and pharyngeal arches, implying co-option of AP-2 genes by neural crest cells early in vertebrate evolution. Expression in non-neural ectoderm is a conserved feature in amphioxus and vertebrates, suggesting an ancient role for AP-2 genes in this tissue. There is also common expression in subsets of ventrolateral neurons in the anterior neural tube, consistent with a primitive role in brain development. Comparison of AP-2 expression in axolotl and lamprey suggests an elaboration of cranial neural crest patterning in gnathostomes. However, migration of AP-2-expressing neural crest cells medial to the pharyngeal arch mesoderm appears to be a primitive feature retained in all vertebrates. Because AP-2 has essential roles in cranial neural crest differentiation and proliferation, the co-option of AP-2 by neural crest cells in the vertebrate lineage was a potentially crucial event in vertebrate evolution.

  5. The first 50Myr of dinosaur evolution: macroevolutionary pattern and morphological disparity.

    Science.gov (United States)

    Brusatte, Stephen L; Benton, Michael J; Ruta, Marcello; Lloyd, Graeme T

    2008-12-23

    The evolutionary radiation of dinosaurs in the Late Triassic and Early Jurassic was a pivotal event in the Earth's history but is poorly understood, as previous studies have focused on vague driving mechanisms and have not untangled different macroevolutionary components (origination, diversity, abundance and disparity). We calculate the morphological disparity (morphospace occupation) of dinosaurs throughout the Late Triassic and Early Jurassic and present new measures of taxonomic diversity. Crurotarsan archosaurs, the primary dinosaur 'competitors', were significantly more disparate than dinosaurs throughout the Triassic, but underwent a devastating extinction at the Triassic-Jurassic boundary. However, dinosaur disparity showed only a slight non-significant increase after this event, arguing against the hypothesis of ecological release-driven morphospace expansion in the Early Jurassic. Instead, the main jump in dinosaur disparity occurred between the Carnian and Norian stages of the Triassic. Conversely, dinosaur diversity shows a steady increase over this time, and measures of diversification and faunal abundance indicate that the Early Jurassic was a key episode in dinosaur evolution. Thus, different aspects of the dinosaur radiation (diversity, disparity and abundance) were decoupled, and the overall macroevolutionary pattern of the first 50Myr of dinosaur evolution is more complex than often considered.

  6. Using phylogenomic patterns and gene ontology to identify proteins of importance in plant evolution.

    Science.gov (United States)

    Cibrián-Jaramillo, Angélica; De la Torre-Bárcena, Jose E; Lee, Ernest K; Katari, Manpreet S; Little, Damon P; Stevenson, Dennis W; Martienssen, Rob; Coruzzi, Gloria M; DeSalle, Rob

    2010-07-12

    We use measures of congruence on a combined expressed sequenced tag genome phylogeny to identify proteins that have potential significance in the evolution of seed plants. Relevant proteins are identified based on the direction of partitioned branch and hidden support on the hypothesis obtained on a 16-species tree, constructed from 2,557 concatenated orthologous genes. We provide a general method for detecting genes or groups of genes that may be under selection in directions that are in agreement with the phylogenetic pattern. Gene partitioning methods and estimates of the degree and direction of support of individual gene partitions to the overall data set are used. Using this approach, we correlate positive branch support of specific genes for key branches in the seed plant phylogeny. In addition to basic metabolic functions, such as photosynthesis or hormones, genes involved in posttranscriptional regulation by small RNAs were significantly overrepresented in key nodes of the phylogeny of seed plants. Two genes in our matrix are of critical importance as they are involved in RNA-dependent regulation, essential during embryo and leaf development. These are Argonaute and the RNA-dependent RNA polymerase 6 found to be overrepresented in the angiosperm clade. We use these genes as examples of our phylogenomics approach and show that identifying partitions or genes in this way provides a platform to explain some of the more interesting organismal differences among species, and in particular, in the evolution of plants.

  7. Linking pattern to process in cultural evolution: explaining material culture diversity among the Northern Khanty of Northwest Siberia

    OpenAIRE

    Jordan, P.

    2009-01-01

    Book description: This volume offers an integrative approach to the application of evolutionary theory in studies of cultural transmission and social evolution and reveals the enormous range of ways in which Darwinian ideas can lead to productive empirical research, the touchstone of any worthwhile theoretical perspective. While many recent works on cultural evolution adopt a specific theoretical framework, such as dual inheritance theory or human behavioral ecology, Pattern and Process in Cu...

  8. Conserved phenotypic variation patterns, evolution along lines of least resistance, and departure due to selection in fossil rodents.

    Science.gov (United States)

    Renaud, Sabrina; Auffray, Jean-Christophe; Michaux, Jacques

    2006-08-01

    Within a group of organisms, some morphologies are more readily generated than others due to internal developmental constraints. Such constraints can channel evolutionary changes into directions corresponding to the greatest intraspecific variation. Long-term evolutionary outputs, however, depend on the stability of these intraspecific patterns of variation over time and from the interplay between internal constraints and selective regimes. To address these questions, the relationship between the structure of phenotypic variance covariance matrices and direction of morphological evolution was investigated using teeth of fossil rodents. One lineage considered here leads to Stephanomys, a highly specialized genus characterized by a dental pattern supposedly favoring grass eating. Stephanomys evolved in the context of directional selection related to the climatic trend of global cooling causing an increasing proportion of grasslands in southwestern Europe. The initial divergence (up to approximately 6.5 mya) was channeled along the direction of greatest intraspecific variation, whereas after 6.5 mya, morphological evolution departed from the direction favored by internal constraints. This departure from the "lines of least resistance" was likely the consequence of an environmental degradation causing a selective gradient strong enough to overwhelm the constraints to phenotypic evolution. However, in a context of stabilizing selection, these constraints actually channel evolution, as exemplified by the lineage of Apodemus. This lineage retained a primitive diet and dental pattern over the last 10 myr. Limited morphological changes occurred nevertheless in accordance with the main patterns of intraspecific variation. The importance of these lines of least resistance directing long-term morphological evolution may explain parallel evolution of some dental patterns in murine evolution.

  9. Non-linear power law approach for spatial and temporal pattern analysis of salt marsh evolution

    Science.gov (United States)

    Taramelli, A.; Cornacchia, L.; Valentini, E.; Bozzeda, F.

    2013-11-01

    Many complex systems on the Earth surface show non-equilibrium fluctuations, often determining the spontaneous evolution towards a critical state. In this context salt marshes are characterized by complex patterns both in geomorphological and ecological features, which often appear to be strongly correlated. A striking feature in salt marshes is vegetation distribution, which can self-organize in patterns over time and space. Self-organized patchiness of vegetation can often give rise to power law relationships in the frequency distribution of patch sizes. In cases where the whole distribution does not follow a power law, the variance of scale in its tail may often be disregarded. To this end, the research aims at how changes in the main climatic and hydrodynamic variables may influence such non-linearity, and how numerical thresholds can describe this. Since it would be difficult to simultaneously monitor the presence and typology of vegetation and channel sinuosity through in situ data, and even harder to analyze them over medium to large time-space scales, remote sensing offers the ability to analyze the scale invariance of patchiness distributions. Here, we focus on a densely vegetated and channelized salt marsh (Scheldt estuary Belgium-the Netherlands) by means of the sub-pixel analysis on satellite images to calculate the non-linearity in the values of the power law exponents due to the variance of scale. The deviation from power laws represents stochastic conditions under climate drivers that can be hybridized on the basis of a fuzzy Bayesian generative algorithm. The results show that the hybrid approach is able to simulate the non-linearity inherent to the system and clearly show the existence of a link between the autocorrelation level of the target variable (i.e. size of vegetation patches), due to its self-organization properties, and the influence exerted on it by the external drivers (i.e. climate and hydrology). Considering the results of the

  10. Head First 2D Geometry

    CERN Document Server

    Fallow), Stray

    2009-01-01

    Having trouble with geometry? Do Pi, The Pythagorean Theorem, and angle calculations just make your head spin? Relax. With Head First 2D Geometry, you'll master everything from triangles, quads and polygons to the time-saving secrets of similar and congruent angles -- and it'll be quick, painless, and fun. Through entertaining stories and practical examples from the world around you, this book takes you beyond boring problems. You'll actually use what you learn to make real-life decisions, like using angles and parallel lines to crack a mysterious CSI case. Put geometry to work for you, and

  11. 2D Cooling of Magnetized Neutron Stars

    CERN Document Server

    Aguilera, Deborah N; Miralles, Juan A

    2007-01-01

    Context: Many thermally emitting isolated neutron stars have magnetic fields larger than 10^{13}G. A realistic cooling model should be reconsidered including the presence of high magnetic fields. Aims: We investigate the effects of anisotropic temperature distribution and Joule heating on the cooling of magnetized neutron stars. Methods: The 2D heat transfer equation with anisotropic thermal conductivity tensor and including all relevant neutrino emission processes is solved for realistic models of the neutron star interior and crust. Results: The presence of the magnetic field affects significantly the thermal surface distribution and the cooling history during both, the early neutrino cooling era and the late photon cooling era. Conclusions: There is a huge effect of the Joule heating on the thermal evolution of strongly magnetized neutron stars. Magnetic fields and Joule heating play a key role in maintaining magnetars warm for a long time. Moreover, this effect is also important for intermediate field neu...

  12. Complex dynamics underlie the evolution of imperfect wing pattern convergence in butterflies.

    Science.gov (United States)

    Finkbeiner, Susan D; Briscoe, Adriana D; Mullen, Sean P

    2017-01-04

    Adaptive radiation is characterized by rapid diversification that is strongly associated with ecological specialization. However, understanding the evolutionary mechanisms fueling adaptive diversification requires a detailed knowledge of how natural selection acts at multiple life-history stages. Butterflies within the genus Adelpha represent one of the largest and most diverse butterfly lineages in the Neotropics. Although Adelpha species feed on an extraordinary diversity of larval hosts, convergent evolution is widespread in this group, suggesting that selection for mimicry may contribute to adaptive divergence among species. To investigate this hypothesis, we conducted predation studies in Costa Rica using artificial butterfly facsimiles. Specifically, we predicted that nontoxic, palatable Adelpha species that do not feed on host plants in the family Rubiaceae would benefit from sharing a locally convergent wing pattern with the presumably toxic Rubiaceae-feeding species via reduced predation. Contrary to expectations, we found that the presumed mimic was attacked significantly more than its locally convergent model at a frequency paralleling attack rates on both novel and palatable prey. Although these data reveal the first evidence for protection from avian predators by the supposed toxic, Rubiaceae-feeding Adelpha species, we conclude that imprecise mimetic patterns have high costs for Batesian mimics in the tropics.

  13. Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns

    LENUS (Irish Health Repository)

    Sen, Lin

    2011-06-03

    mutations put forward the conclusion that this evolutionary scenario has been possible through a complex interplay between adaptive mutations, often structurally destabilizing, and compensatory mutations. Our results unearth patterns of evolution that have likely optimized the Rubisco activity and uncover mutational dynamics useful in the molecular engineering of enzymatic activities. Reviewers This article was reviewed by Prof. Christian Blouin (nominated by Dr W Ford Doolittle), Dr Endre Barta (nominated by Dr Sandor Pongor), and Dr Nicolas Galtier.

  14. Multiple patterns of writing disorders in dementia of the Alzheimer type and their evolution.

    Science.gov (United States)

    Luzzatti, Claudio; Laiacona, Marcella; Agazzi, Daniela

    2003-01-01

    This paper reports the results obtained from a writing task given to 23 Italian patients suffering from mild to moderate dementia of the Alzheimer's type (DAT). Spelling performance was tested with a task that taps the sub-word-level (spelling of regular words and nonwords), and the lexical route (spelling of regular and irregular words), in line with contemporary models of writing. Each patient's performance was classified according to the emergence of dissociated patterns of damage between regular words and nonwords and between regular and irregular words. The 23 DAT patients span the whole spectrum of dysgraphic taxonomy; five showed the characteristic pattern of impairment of surface dysgraphia, two showed the characteristics of phonological dysgraphia, while a mixed pattern (i.e. better performance on regular words compared to irregular words and regular nonwords) emerged in seven cases. Three patients presented undifferentiated writing disorders, two were completely agraphic, while four patients showed only minimal or no writing defects. The rate of dissociated impairments in the lexical and the sub-word-level routine is very similar to that observed after acute focal brain damage, which contradicts the hypothesis that degenerative brain damage selectively impairs writing performance along the lexical-semantic route. To test the hypothesis that surface sub-word-level processing abilities are affected only during the evolution of the disease, nine patients were tested longitudinally after an interval of 6-12 months. Once again, the data showed high variability across subjects, and do not seem to support involvement of the sub-word-level spelling routine only at a late stage in the development of the disease.

  15. Flow pattern and lift evolution of hydrofoil with control of electro-magnetic forces

    Institute of Scientific and Technical Information of China (English)

    CHEN YaoHui; FAN BaoChun; CHEN ZhiHua; LI HongZhi

    2009-01-01

    The Initial responses and evolutions of the flow pattern and lift coefficient of a hydrofoil under the ac-tion of electro-magnetic (Lorentz) force have been studied experimentally and numerically,and trace particle methods are employed for them.With the introduction of BVF (boundary vortex flux),the quantitative relation among Lorentz forces,BVF and lifts is deduced.The influences of flow patterns on the hydrofoil lift coefficient have been discussed based on the BVF distribution,and the flow control mechanism of Lorentz force for a hydrofoil has been elucidated.Our results show that the flow pattern and lift of the hydrofoil vary periodically without any force.However,with the action of streamwise Lorentz forces,the separation point on the hydrofoil surface moves backward with a certain velocity,which makes the flow field steady finally.The streamwise Lorentz force raises the foil lift due to the Increase of BVF intensity.On the other hand,Lorentz force also increases the hydrofoil surface pres-sure,which makes the lift decrease.However,the factor leading to the lift enhancement is determinant,therefore,the Lorentz force on the suction side can increase the lift,and the stronger the Lorentz force,the larger the lift enhancement.Our results also show that the localized Lorentz force can also both suppress the flow separation and increase the hydrofoil lift coefficient,furthermore,the Lorentz force located on the tail acts better than that located on the front.

  16. 2D SIMPLIFIED SERVO VALVE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A novel pilot stage valve called simplified 2D valve, which utilizes both rotary and linear motions of a single spool, is presented.The rotary motion of the spool incorporating hydraulic resistance bridge, formed by a damper groove and a crescent overlap opening, is utilized as pilot to actuate linear motion of the spool.A criterion for stability is derived from the linear analysis of the valve.Special experiments are designed to acquire the mechanical stiffness, the pilot leakage and the step response.It is shown that the sectional size of the spiral groove affects the dynamic response and the stiffness contradictorily and is also very sensitive to the pilot leakage.Therefore, it is necessary to establish a balance between the static and dynamic characteristics in deciding the structural parameters.Nevertheless, it is possible to sustain the dynamic response at a fairly high level, while keeping the leakage of the pilot stage at an acceptable level.

  17. Personalized 2D color maps

    KAUST Repository

    Waldin, Nicholas

    2016-06-24

    2D color maps are often used to visually encode complex data characteristics such as heat or height. The comprehension of color maps in visualization is affected by the display (e.g., a monitor) and the perceptual abilities of the viewer. In this paper we present a novel method to measure a user\\'s ability to distinguish colors of a two-dimensional color map on a given monitor. We show how to adapt the color map to the user and display to optimally compensate for the measured deficiencies. Furthermore, we improve user acceptance of the calibration procedure by transforming the calibration into a game. The user has to sort colors along a line in a 3D color space in a competitive fashion. The errors the user makes in sorting these lines are used to adapt the color map to his perceptual capabilities.

  18. A Pattern Language for the Evolution of Component-based Software Architectures

    DEFF Research Database (Denmark)

    Ahmad, Aakash; Jamshidi, Pooyan; Pahl, Claus

    2013-01-01

    ) as a complementary and integrated phase to facilitate reuse-driven architecture change execution (pattern language application). Reuse-knowledge in the proposed pattern language is expressed as a formalised collection of interconnected-patterns. Individual patterns in the language build on each other to facilitate...... as a measure of selecting the most appropriate pattern(s) from the language collection. The pattern language itself continuously evolves with an incremental acquisition of new patterns from change logs over time....

  19. [Prediction method of rural landscape pattern evolution based on life cycle: a case study of Jinjing Town, Hunan Province, China].

    Science.gov (United States)

    Ji, Xiang; Liu, Li-Ming; Li, Hong-Qing

    2014-11-01

    Taking Jinjing Town in Dongting Lake area as a case, this paper analyzed the evolution of rural landscape patterns by means of life cycle theory, simulated the evolution cycle curve, and calculated its evolution period, then combining CA-Markov model, a complete prediction model was built based on the rule of rural landscape change. The results showed that rural settlement and paddy landscapes of Jinjing Town would change most in 2020, with the rural settlement landscape increased to 1194.01 hm2 and paddy landscape greatly reduced to 3090.24 hm2. The quantitative and spatial prediction accuracies of the model were up to 99.3% and 96.4%, respectively, being more explicit than single CA-Markov model. The prediction model of rural landscape patterns change proposed in this paper would be helpful for rural landscape planning in future.

  20. Quantum coherence selective 2D Raman-2D electronic spectroscopy.

    Science.gov (United States)

    Spencer, Austin P; Hutson, William O; Harel, Elad

    2017-03-10

    Electronic and vibrational correlations report on the dynamics and structure of molecular species, yet revealing these correlations experimentally has proved extremely challenging. Here, we demonstrate a method that probes correlations between states within the vibrational and electronic manifold with quantum coherence selectivity. Specifically, we measure a fully coherent four-dimensional spectrum which simultaneously encodes vibrational-vibrational, electronic-vibrational and electronic-electronic interactions. By combining near-impulsive resonant and non-resonant excitation, the desired fifth-order signal of a complex organic molecule in solution is measured free of unwanted lower-order contamination. A critical feature of this method is electronic and vibrational frequency resolution, enabling isolation and assignment of individual quantum coherence pathways. The vibronic structure of the system is then revealed within an otherwise broad and featureless 2D electronic spectrum. This method is suited for studying elusive quantum effects in which electronic transitions strongly couple to phonons and vibrations, such as energy transfer in photosynthetic pigment-protein complexes.

  1. Development and evolution of dentition pattern and tooth order in the skates and rays (batoidea; chondrichthyes.

    Directory of Open Access Journals (Sweden)

    Charlie J Underwood

    Full Text Available Shark and ray (elasmobranch dentitions are well known for their multiple generations of teeth, with isolated teeth being common in the fossil record. However, how the diverse dentitions characteristic of elasmobranchs form is still poorly understood. Data on the development and maintenance of the dental patterning in this major vertebrate group will allow comparisons to other morphologically diverse taxa, including the bony fishes, in order to identify shared pattern characters for the vertebrate dentition as a whole. Data is especially lacking from the Batoidea (skates and rays, hence our objective is to compile data on embryonic and adult batoid tooth development contributing to ordering of the dentition, from cleared and stained specimens and micro-CT scans, with 3D rendered models. We selected species (adult and embryonic spanning phylogenetically significant batoid clades, such that our observations may raise questions about relationships within the batoids, particularly with respect to current molecular-based analyses. We include developmental data from embryos of recent model organisms Leucoraja erinacea and Raja clavata to evaluate the earliest establishment of the dentition. Characters of the batoid dentition investigated include alternate addition of teeth as offset successional tooth rows (versus single separate files, presence of a symphyseal initiator region (symphyseal tooth present, or absent, but with two parasymphyseal teeth and a restriction to tooth addition along each jaw reducing the number of tooth families, relative to addition of successor teeth within each family. Our ultimate aim is to understand the shared characters of the batoids, and whether or not these dental characters are shared more broadly within elasmobranchs, by comparing these to dentitions in shark outgroups. These developmental morphological analyses will provide a solid basis to better understand dental evolution in these important vertebrate groups as

  2. Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution.

    Directory of Open Access Journals (Sweden)

    Nelle Lambert

    Full Text Available The developmental mechanisms through which the cerebral cortex increased in size and complexity during primate evolution are essentially unknown. To uncover genetic networks active in the developing cerebral cortex, we combined three-dimensional reconstruction of human fetal brains at midgestation and whole genome expression profiling. This novel approach enabled transcriptional characterization of neurons from accurately defined cortical regions containing presumptive Broca and Wernicke language areas, as well as surrounding associative areas. We identified hundreds of genes displaying differential expression between the two regions, but no significant difference in gene expression between left and right hemispheres. Validation by qRTPCR and in situ hybridization confirmed the robustness of our approach and revealed novel patterns of area- and layer-specific expression throughout the developing cortex. Genes differentially expressed between cortical areas were significantly associated with fast-evolving non-coding sequences harboring human-specific substitutions that could lead to divergence in their repertoires of transcription factor binding sites. Strikingly, while some of these sequences were accelerated in the human lineage only, many others were accelerated in chimpanzee and/or mouse lineages, indicating that genes important for cortical development may be particularly prone to changes in transcriptional regulation across mammals. Genes differentially expressed between cortical regions were also enriched for transcriptional targets of FoxP2, a key gene for the acquisition of language abilities in humans. Our findings point to a subset of genes with a unique combination of cortical areal expression and evolutionary patterns, suggesting that they play important roles in the transcriptional network underlying human-specific neural traits.

  3. Phylogenomic analyses reveal convergent patterns of adaptive evolution in elephant and human ancestries.

    Science.gov (United States)

    Goodman, Morris; Sterner, Kirstin N; Islam, Munirul; Uddin, Monica; Sherwood, Chet C; Hof, Patrick R; Hou, Zhuo-Cheng; Lipovich, Leonard; Jia, Hui; Grossman, Lawrence I; Wildman, Derek E

    2009-12-01

    Specific sets of brain-expressed genes, such as aerobic energy metabolism genes, evolved adaptively in the ancestry of humans and may have evolved adaptively in the ancestry of other large-brained mammals. The recent addition of genomes from two afrotherians (elephant and tenrec) to the expanding set of publically available sequenced mammalian genomes provided an opportunity to test this hypothesis. Elephants resemble humans by having large brains and long life spans; tenrecs, in contrast, have small brains and short life spans. Thus, we investigated whether the phylogenomic patterns of adaptive evolution are more similar between elephant and human than between either elephant and tenrec lineages or human and mouse lineages, and whether aerobic energy metabolism genes are especially well represented in the elephant and human patterns. Our analyses encompassed approximately 6,000 genes in each of these lineages with each gene yielding extensive coding sequence matches in interordinal comparisons. Each gene's nonsynonymous and synonymous nucleotide substitution rates and dN/dS ratios were determined. Then, from gene ontology information on genes with the higher dN/dS ratios, we identified the more prevalent sets of genes that belong to specific functional categories and that evolved adaptively. Elephant and human lineages showed much slower nucleotide substitution rates than tenrec and mouse lineages but more adaptively evolved genes. In correlation with absolute brain size and brain oxygen consumption being largest in elephants and next largest in humans, adaptively evolved aerobic energy metabolism genes were most evident in the elephant lineage and next most evident in the human lineage.

  4. Development and evolution of dentition pattern and tooth order in the skates and rays (batoidea; chondrichthyes).

    Science.gov (United States)

    Underwood, Charlie J; Johanson, Zerina; Welten, Monique; Metscher, Brian; Rasch, Liam J; Fraser, Gareth J; Smith, Moya Meredith

    2015-01-01

    Shark and ray (elasmobranch) dentitions are well known for their multiple generations of teeth, with isolated teeth being common in the fossil record. However, how the diverse dentitions characteristic of elasmobranchs form is still poorly understood. Data on the development and maintenance of the dental patterning in this major vertebrate group will allow comparisons to other morphologically diverse taxa, including the bony fishes, in order to identify shared pattern characters for the vertebrate dentition as a whole. Data is especially lacking from the Batoidea (skates and rays), hence our objective is to compile data on embryonic and adult batoid tooth development contributing to ordering of the dentition, from cleared and stained specimens and micro-CT scans, with 3D rendered models. We selected species (adult and embryonic) spanning phylogenetically significant batoid clades, such that our observations may raise questions about relationships within the batoids, particularly with respect to current molecular-based analyses. We include developmental data from embryos of recent model organisms Leucoraja erinacea and Raja clavata to evaluate the earliest establishment of the dentition. Characters of the batoid dentition investigated include alternate addition of teeth as offset successional tooth rows (versus single separate files), presence of a symphyseal initiator region (symphyseal tooth present, or absent, but with two parasymphyseal teeth) and a restriction to tooth addition along each jaw reducing the number of tooth families, relative to addition of successor teeth within each family. Our ultimate aim is to understand the shared characters of the batoids, and whether or not these dental characters are shared more broadly within elasmobranchs, by comparing these to dentitions in shark outgroups. These developmental morphological analyses will provide a solid basis to better understand dental evolution in these important vertebrate groups as well as the

  5. Patterns of Protein Evolution in Cytochrome c Oxidase 1 (COI) from the Class Arachnida.

    Science.gov (United States)

    Young, Monica R; Hebert, Paul D N

    2015-01-01

    Because sequence information is now available for the 648bp barcode region of cytochrome c oxidase 1 (COI) from more than 400,000 animal species, this gene segment can be used to probe patterns of mitochondrial evolution. The present study examines levels of amino acid substitution and the frequency of indels in COI from 4177 species of arachnids, including representatives from all 16 orders and 43% of its families (267/625). It examines divergences at three taxonomic levels-among members of each order to an outgroup, among families in each order and among BINs, a species proxy, in each family. Order Distances vary fourfold (0.10-0.39), while the mean of the Family Distances for the ten orders ranges fivefold (0.07-0.35). BIN Distances show great variation, ranging from 0.01 or less in 12 families to more than 0.25 in eight families. Patterns of amino acid substitution in COI are generally congruent with previously reported variation in nucleotide substitution rates in arachnids, but provide some new insights, such as clear rate acceleration in the Opiliones. By revealing a strong association between elevated rates of nucleotide and amino acid substitution, this study builds evidence for the selective importance of the rate variation among arachnid lineages. Moreover, it establishes that groups whose COI genes have elevated levels of amino acid substitution also regularly possess indels, a dramatic form of protein reconfiguration. Overall, this study suggests that the mitochondrial genome of some arachnid groups is dynamic with high rates of amino acid substitution and frequent indels, while it is 'locked down' in others. Dynamic genomes are most prevalent in arachnids with short generation times, but the possible impact of breeding system deserves investigation since many of the rapidly evolving lineages reproduce by haplodiploidy, a mode of reproduction absent in 'locked down' taxa.

  6. Patterns of Protein Evolution in Cytochrome c Oxidase 1 (COI from the Class Arachnida.

    Directory of Open Access Journals (Sweden)

    Monica R Young

    Full Text Available Because sequence information is now available for the 648bp barcode region of cytochrome c oxidase 1 (COI from more than 400,000 animal species, this gene segment can be used to probe patterns of mitochondrial evolution. The present study examines levels of amino acid substitution and the frequency of indels in COI from 4177 species of arachnids, including representatives from all 16 orders and 43% of its families (267/625. It examines divergences at three taxonomic levels-among members of each order to an outgroup, among families in each order and among BINs, a species proxy, in each family. Order Distances vary fourfold (0.10-0.39, while the mean of the Family Distances for the ten orders ranges fivefold (0.07-0.35. BIN Distances show great variation, ranging from 0.01 or less in 12 families to more than 0.25 in eight families. Patterns of amino acid substitution in COI are generally congruent with previously reported variation in nucleotide substitution rates in arachnids, but provide some new insights, such as clear rate acceleration in the Opiliones. By revealing a strong association between elevated rates of nucleotide and amino acid substitution, this study builds evidence for the selective importance of the rate variation among arachnid lineages. Moreover, it establishes that groups whose COI genes have elevated levels of amino acid substitution also regularly possess indels, a dramatic form of protein reconfiguration. Overall, this study suggests that the mitochondrial genome of some arachnid groups is dynamic with high rates of amino acid substitution and frequent indels, while it is 'locked down' in others. Dynamic genomes are most prevalent in arachnids with short generation times, but the possible impact of breeding system deserves investigation since many of the rapidly evolving lineages reproduce by haplodiploidy, a mode of reproduction absent in 'locked down' taxa.

  7. Computational Experiment Approach to Controlled Evolution of Procurement Pattern in Cluster Supply Chain

    Directory of Open Access Journals (Sweden)

    Xiao Xue

    2015-01-01

    Full Text Available Companies have been aware of the benefits of developing Cluster Supply Chains (CSCs, and they are spending a great deal of time and money attempting to develop the new business pattern. Yet, the traditional techniques for identifying CSCs have strong theoretical antecedents, but seem to have little traction in the field. We believe this is because the standard techniques fail to capture evolution over time, nor provide useful intervention measures to reach goals. To address these problems, we introduce an agent-based modeling approach to evaluate CSCs. Taking collaborative procurement as research object, our approach is composed of three parts: model construction, model instantiation, and computational experiment. We use the approach to explore the service charging policy problem in collaborative procurement. Three kinds of service charging polices are compared in the same experiment environment. Finally, “Fixed Cost” is identified as the optimal policy under the stable market environment. The case study can help us to understand the workflow of applying the approach, and provide valuable decision support applications to industry.

  8. Skeletal development in sloths and the evolution of mammalian vertebral patterning.

    Science.gov (United States)

    Hautier, Lionel; Weisbecker, Vera; Sánchez-Villagra, Marcelo R; Goswami, Anjali; Asher, Robert J

    2010-11-02

    Mammals show a very low level of variation in vertebral count, particularly in the neck. Phenotypes exhibited at various stages during the development of the axial skeleton may play a key role in testing mechanisms recently proposed to explain this conservatism. Here, we provide osteogenetic data that identify developmental criteria with which to recognize cervical vs. noncervical vertebrae in mammals. Except for sloths, all mammals show the late ossification of the caudal-most centra in the neck after other centra and neural arches. In sloths with 8-10 ribless neck vertebrae, the caudal-most neck centra ossify early, matching the pattern observed in cranial thoracic vertebrae of other mammals. Accordingly, we interpret the ribless neck vertebrae of three-toed sloths caudal to V7 as thoracic based on our developmental criterion. Applied to the unusual vertebral phenotype of long-necked sloths, these data support the interpretation that elements of the axial skeleton with origins from distinct mesodermal tissues have repatterned over the course of evolution.

  9. Patterns of proliferative activity in the colonic crypt determine crypt stability and rates of somatic evolution.

    Directory of Open Access Journals (Sweden)

    Rui Zhao

    Full Text Available Epithelial cells in the colon are arranged in cylindrical structures called crypts in which cellular proliferation and migration are tightly regulated. We hypothesized that the proliferation patterns of cells may determine the stability of crypts as well as the rates of somatic evolution towards colorectal tumorigenesis. Here, we propose a linear process model of colonic epithelial cells that explicitly takes into account the proliferation kinetics of cells as a function of cell position within the crypt. Our results indicate that proliferation kinetics has significant influence on the speed of cell movement, kinetics of mutation propagation, and sensitivity of the system to selective effects of mutated cells. We found that, of all proliferation curves tested, those with mitotic activities concentrated near the stem cell, including the actual proliferation kinetics determined in in vivo labeling experiments, have a greater ability of delaying the rate of mutation accumulation in colonic stem cells compared to hypothetical proliferation curves with mitotic activities focused near the top of the crypt column. Our model can be used to investigate the dynamics of proliferation and mutation accumulation in spatially arranged tissues.

  10. Evolution of host utilization patterns in the seed beetle genus Mimosestes Bridwell (Coleoptera: Chrysomelidae: Bruchinae).

    Science.gov (United States)

    Kato, Toshihide; Bonet, Arturo; Yoshitake, Hiraku; Romero-Nápoles, Jesús; Jinbo, Utsugi; Ito, Motomi; Shimada, Masakazu

    2010-06-01

    The evolutionary history of diet breadth expansion and intergeneric host shifts in the seed beetle genus Mimosestes were reconstructed to investigate the process of host range expansion in phytophagous insects. The evolutionary correlation between diet breadth and variation in oviposition behavior of Mimosestes was also examined to estimate the process of generalist evolution within the genus. Ancestral state reconstruction based on a molecular phylogeny inferred from three mitochondrial markers (16S rRNA, 12S rRNA, and COI) and one nuclear marker (EF-1alpha) revealed that host utilization patterns were shaped by repeated colonizations to novel or pre-adapted host plants. Neither plant genus and species group level host conservatism nor an evolutionary tendency toward specialization was found in the genus, contrary to the expectations of plant-insect co-evolutionary theory. In addition, statistical analyses revealed that diet breadth was significantly correlated with oviposition behavior, suggesting that behavioral factors such as the oviposition preferences of female seed beetles affect the expansion of diet breadth in generalists.

  11. Patterns of microsatellite evolution inferred from the Helianthus annuus (Asteraceae) transcriptome

    Indian Academy of Sciences (India)

    Sreepriya Pramod; Andy D. Perkins; Mark E. Welch

    2014-08-01

    The distribution of microsatellites in exons, and their association with gene ontology (GO) terms is explored to elucidate patterns of microsatellite evolution in the common sunflower, Helianthus annuus. The relative position, motif, size and level of impurity were estimated for each microsatellite in the unigene database available from the Compositae Genome Project (CGP), and statistical analyses were performed to determine if differences in microsatellite distributions and enrichment within certain GO terms were significant. There are more translated than untranslated microsatellites, implying that many bring about structural changes in proteins. However, the greatest density is observed within the UTRs, particularly 5′UTRs. Further, UTR microsatellites are purer and longer than coding region microsatellites. This suggests that UTR microsatellites are either younger and under more relaxed constraints, or that purifying selection limits impurities, and directional selection favours their expansion. GOs associated with response to various environmental stimuli including water deprivation and salt stress were significantly enriched with microsatellites. This may suggest that these GOs are more labile in plant genomes, or that selection has favoured the maintenance of microsatellites in these genes over others. This study shows that the distribution of transcribed microsatellites in H. annuus is nonrandom, the coding region microsatellites are under greater constraint compared to the UTR microsatellites, and that these sequences are enriched within genes that regulate plant responses to environmental stress and stimuli.

  12. Patterns of microsatellite evolution inferred from the Helianthus annuus (Asteraceae) transcriptome.

    Science.gov (United States)

    Pramod, Sreepriya; Perkins, Andy D; Welch, Mark E

    2014-08-01

    The distribution of microsatellites in exons, and their association with gene ontology (GO) terms is explored to elucidate patterns of microsatellite evolution in the common sunflower, Helianthus annuus. The relative position, motif, size and level of impurity were estimated for each microsatellite in the unigene database available from the Compositae Genome Project (CGP), and statistical analyses were performed to determine if differences in microsatellite distributions and enrichment within certain GO terms were significant. There are more translated than untranslated microsatellites, implying that many bring about structural changes in proteins. However, the greatest density is observed within the UTRs, particularly 5'UTRs. Further, UTR microsatellites are purer and longer than coding region microsatellites. This suggests that UTR microsatellites are either younger and under more relaxed constraints, or that purifying selection limits impurities, and directional selection favours their expansion. GOs associated with response to various environmental stimuli including water deprivation and salt stress were significantly enriched with microsatellites. This may suggest that these GOs are more labile in plant genomes, or that selection has favoured the maintenance of microsatellites in these genes over others. This study shows that the distribution of transcribed microsatellites in H. annuus is nonrandom, the coding region microsatellites are under greater constraint compared to the UTR microsatellites, and that these sequences are enriched within genes that regulate plant responses to environmental stress and stimuli.

  13. First Principles Calculations of Electronic Excitations in 2D Materials

    DEFF Research Database (Denmark)

    Rasmussen, Filip Anselm

    -thin electronics and high efficiency solar cells. Contrary to many other nano-materials, methods for large scale fabrication and patterning have already been demonstrated and the first real technological applications have already be showcased. Still the technology is very young and the number of well-studied 2D...... materials are few. However as the list of 2D materials is growing it is necessary to investigate their fundamental structural, electronic and optical properties. These are determined by the atomic and electronic structure of the materials that can quite accurately predicted by computational quantum...... as if it is being screened by the electrons in the material. This method has been very successful for calculating quasiparticle energies of bulk materials but results have been more varying for 2D materials. The reason is that the 2D confined electrons are less able to screen the added charge and some...

  14. ChIP-Seq-Annotated Heliconius erato Genome Highlights Patterns of cis-Regulatory Evolution in Lepidoptera

    Directory of Open Access Journals (Sweden)

    James J. Lewis

    2016-09-01

    Full Text Available Uncovering phylogenetic patterns of cis-regulatory evolution remains a fundamental goal for evolutionary and developmental biology. Here, we characterize the evolution of regulatory loci in butterflies and moths using chromatin immunoprecipitation sequencing (ChIP-seq annotation of regulatory elements across three stages of head development. In the process we provide a high-quality, functionally annotated genome assembly for the butterfly, Heliconius erato. Comparing cis-regulatory element conservation across six lepidopteran genomes, we find that regulatory sequences evolve at a pace similar to that of protein-coding regions. We also observe that elements active at multiple developmental stages are markedly more conserved than elements with stage-specific activity. Surprisingly, we also find that stage-specific proximal and distal regulatory elements evolve at nearly identical rates. Our study provides a benchmark for genome-wide patterns of regulatory element evolution in insects, and it shows that developmental timing of activity strongly predicts patterns of regulatory sequence evolution.

  15. Learn Unity for 2D game development

    CERN Document Server

    Thorn, Alan

    2013-01-01

    The only Unity book specifically covering 2D game development Written by Alan Thorn, experience game developer and author of seven books on game programming Hands-on examples of all major aspects of 2D game development using Unity

  16. Handling and Use of Oxygen by Pancrustaceans: Conserved Patterns and the Evolution of Respiratory Structures.

    Science.gov (United States)

    Harrison, Jon F

    2015-11-01

    The handling and use of oxygen are central to physiological function of all pancrustaceans. Throughout the Pancrustacea, ventilation is controlled by a central oxygen-sensitive pattern generator. The ancestral condition was likely to achieve ventilation of the gills via leg-associated or mouth-associated muscles, but in insects and some air-breathing crustaceans, new muscles were recruited for this purpose, including intersegmental muscles likely used previously for posture and locomotion. Many aspects of the sensing of oxygen and the occurrence of responses to hypoxia (increased ventilation, depressed growth and metabolic rate, developmental changes that enhance the delivery of oxygen) appear common across most pancrustaceans, but there is tremendous variation across species. Some of this can be explained by habitat (e.g., ventilation of the internal medium occurs in terrestrial species and of the external medium in aquatic species; rearing under hypoxia induces tracheal proliferation in terrestrial insects and hemocyanin production in aquatic crustaceans); some plausibly by evolutionary origin of some responses to hypoxia within the Pancrustacea (the most basal arthropods may lack a ventilatory response to hypoxia); and some by the availability of environmental oxygen (animals adapted to survive hypoxia turn on the response to hypoxia at a lower PO2). On average, crustaceans and insects have similar tolerances to prolonged anoxia, but species or life stages from habitats with a danger of being trapped in hypoxia can tolerate longer durations of anoxia. Lactate is the primary anaerobic end-product in crustaceans but some insects have evolved a more diverse array of anaerobic end-products, including ethanol, alanine, succinate, and acetate. Most clades of Pancrustacea are small and lack obvious respiratory structures. Gilled stem-pancrustaceans likely evolved in the Cambrian, and gills persist in large Ostracoda, Malacostraca, and Branchiopoda. Based on currently

  17. Evidence of host-virus co-evolution in tetranucleotide usage patterns of bacteriophages and eukaryotic viruses

    Directory of Open Access Journals (Sweden)

    Ghose Chandrabali

    2006-01-01

    Full Text Available Abstract Background Virus taxonomy is based on morphologic characteristics, as there are no widely used non-phenotypic measures for comparison among virus families. We examined whether there is phylogenetic signal in virus nucleotide usage patterns that can be used to determine ancestral relationships. The well-studied model of tail morphology in bacteriophage classification was used for comparison with nucleotide usage patterns. Tetranucleotide usage deviation (TUD patterns were chosen since they have previously been shown to contain phylogenetic signal similar to that of 16S rRNA. Results We found that bacteriophages have unique TUD patterns, representing genomic signatures that are relatively conserved among those with similar host range. Analysis of TUD-based phylogeny indicates that host influences are important in bacteriophage evolution, and phylogenies containing both phages and their hosts support their co-evolution. TUD-based phylogeny of eukaryotic viruses indicates that they cluster largely based on nucleic acid type and genome size. Similarities between eukaryotic virus phylogenies based on TUD and gene content substantiate the TUD methodology. Conclusion Differences between phenotypic and TUD analysis may provide clues to virus ancestry not previously inferred. As such, TUD analysis provides a complementary approach to morphology-based systems in analysis of virus evolution.

  18. SWS2 visual pigment evolution as a test of historically contingent patterns of plumage color evolution in warblers.

    Science.gov (United States)

    Bloch, Natasha I; Morrow, James M; Chang, Belinda S W; Price, Trevor D

    2015-02-01

    Distantly related clades that occupy similar environments may differ due to the lasting imprint of their ancestors-historical contingency. The New World warblers (Parulidae) and Old World warblers (Phylloscopidae) are ecologically similar clades that differ strikingly in plumage coloration. We studied genetic and functional evolution of the short-wavelength-sensitive visual pigments (SWS2 and SWS1) to ask if altered color perception could contribute to the plumage color differences between clades. We show SWS2 is short-wavelength shifted in birds that occupy open environments, such as finches, compared to those in closed environments, including warblers. Phylogenetic reconstructions indicate New World warblers were derived from a finch-like form that colonized from the Old World 15-20 Ma. During this process, the SWS2 gene accumulated six substitutions in branches leading to New World warblers, inviting the hypothesis that passage through a finch-like ancestor resulted in SWS2 evolution. In fact, we show spectral tuning remained similar across warblers as well as the finch ancestor. Results reject the hypothesis of historical contingency based on opsin spectral tuning, but point to evolution of other aspects of visual pigment function. Using the approach outlined here, historical contingency becomes a generally testable theory in systems where genotype and phenotype can be connected.

  19. Patterns and Implications of Gene Gain and Loss in the Evolution of Prochlorococcus

    Energy Technology Data Exchange (ETDEWEB)

    Lapidus, Alla; Kettler, Gregory C.; Martiny, Adam C.; Huang, Katherine; Zucker, Jeremy; Coleman, Maureen L.; Rodrigue, Sebastien; Chen, Feng; Lapidus, Alla; Ferriera, Steven; Johnson, Justin; Steglich, Claudia; Church, George M.; Richardson, Paul; Chisholm, Sallie W.

    2007-07-30

    Prochlorococcus is a marine cyanobacterium that numerically dominates the mid-latitude oceans and is the smallest known oxygenic phototroph. Numerous isolatesfrom diverse areas of the world's oceans have been studied and shown to be physiologically and genetically distinct. All isolates described thus far can be assigned to either a tightly clustered high-light (HL)-adapted clade, or a more divergent low-light (LL)-adapted group. The 16S rRNA sequences of the entire Prochlorococcus group differ by at most 3percent, and the four initially published genomes revealed patterns of genetic differentiation that help explain physiological differences among the isolates. Here we describe the genomes of eight newly sequenced isolates and combine them with the first four genomes for a comprehensive analysis of the core (shared by all isolates) and flexible genes of the Prochlorococcus group, and the patterns of loss and gain of the flexible genes over the course of evolution. There are 1,273 genes that represent the core shared by all 12 genomes. They are apparently sufficient, according to metabolic reconstruction, to encode a functional cell. We describe a phylogeny for all 12 isolates by subjecting their complete proteomes to three different phylogenetic analyses. For each non-core gene, we used a maximum parsimony method to estimate which ancestor likely first acquired or lost each gene. Many of the genetic differences among isolates, especially for genes involved in outer membrane synthesis and nutrient transport, are found within the same clade. Nevertheless, we identified some genes defining HL and LL ecotypes, and clades within these broad ecotypes, helping to demonstrate the basis of HL and LL adaptations in Prochlorococcus. Furthermore, our estimates of gene gain events allow us to identify highly variable genomic islands that are not apparent through simple pairwise comparisons. These results emphasize the functional roles, especially those connected to outer

  20. Patterns and implications of gene gain and loss in the evolution of Prochlorococcus.

    Directory of Open Access Journals (Sweden)

    Gregory C Kettler

    2007-12-01

    Full Text Available Prochlorococcus is a marine cyanobacterium that numerically dominates the mid-latitude oceans and is the smallest known oxygenic phototroph. Numerous isolates from diverse areas of the world's oceans have been studied and shown to be physiologically and genetically distinct. All isolates described thus far can be assigned to either a tightly clustered high-light (HL-adapted clade, or a more divergent low-light (LL-adapted group. The 16S rRNA sequences of the entire Prochlorococcus group differ by at most 3%, and the four initially published genomes revealed patterns of genetic differentiation that help explain physiological differences among the isolates. Here we describe the genomes of eight newly sequenced isolates and combine them with the first four genomes for a comprehensive analysis of the core (shared by all isolates and flexible genes of the Prochlorococcus group, and the patterns of loss and gain of the flexible genes over the course of evolution. There are 1,273 genes that represent the core shared by all 12 genomes. They are apparently sufficient, according to metabolic reconstruction, to encode a functional cell. We describe a phylogeny for all 12 isolates by subjecting their complete proteomes to three different phylogenetic analyses. For each non-core gene, we used a maximum parsimony method to estimate which ancestor likely first acquired or lost each gene. Many of the genetic differences among isolates, especially for genes involved in outer membrane synthesis and nutrient transport, are found within the same clade. Nevertheless, we identified some genes defining HL and LL ecotypes, and clades within these broad ecotypes, helping to demonstrate the basis of HL and LL adaptations in Prochlorococcus. Furthermore, our estimates of gene gain events allow us to identify highly variable genomic islands that are not apparent through simple pairwise comparisons. These results emphasize the functional roles, especially those connected to

  1. Evolution of the insect body plan as revealed by the Sex combs reduced expression pattern.

    Science.gov (United States)

    Rogers, B T; Peterson, M D; Kaufman, T C

    1997-01-01

    The products of the HOM/Hox homeotic genes form a set of evolutionarily conserved transcription factors that control elaborate developmental processes and specify cell fates in many metazoans. We examined the expression of the ortholog of the homeotic gene Sex combs reduced (Scr) of Drosophila melanogaster in insects of three divergent orders: Hemiptera, Orthoptera and Thysanura. Our data reflect how the conservation and variation of Scr expression has affected the morphological evolution of insects. Whereas the anterior epidermal expression of Scr, in a small part of the posterior maxillary and all of the labial segment, is found to be in common among all four insect orders, the posterior (thoracic) expression domains vary. Unlike what is observed in flies, the Scr orthologs of other insects are not expressed broadly over the first thoracic segment, but are restricted to small patches. We show here that Scr is required for suppression of wings on the prothorax of Drosophila. Moreover, Scr expression at the dorsal base of the prothoracic limb in two other winged insects, crickets (Orthoptera) and milkweed bugs (Hemiptera), is consistent with Scr acting as a suppressor of prothoracic wings in these insects. Scr is also expressed in a small patch of cells near the basitarsal-tibial junction of milkweed bugs, precisely where a leg comb develops, suggesting that Scr promotes comb formation, as it does in Drosophila. Surprisingly, the dorsal prothoracic expression of Scr is also present in the primitively wingless firebrat (Thysanura) and the leg patch is seen in crickets, which have no comb. Mapping both gene expression patterns and morphological characters onto the insect phylogenetic tree demonstrates that in the cases of wing suppression and comb formation the appearance of expression of Scr in the prothorax apparently precedes these specific functions.

  2. Conserved substitution patterns around nucleosome footprints in eukaryotes and Archaea derive from frequent nucleosome repositioning through evolution.

    Directory of Open Access Journals (Sweden)

    Tobias Warnecke

    Full Text Available Nucleosomes, the basic repeat units of eukaryotic chromatin, have been suggested to influence the evolution of eukaryotic genomes, both by altering the propensity of DNA to mutate and by selection acting to maintain or exclude nucleosomes in particular locations. Contrary to the popular idea that nucleosomes are unique to eukaryotes, histone proteins have also been discovered in some archaeal genomes. Archaeal nucleosomes, however, are quite unlike their eukaryotic counterparts in many respects, including their assembly into tetramers (rather than octamers from histone proteins that lack N- and C-terminal tails. Here, we show that despite these fundamental differences the association between nucleosome footprints and sequence evolution is strikingly conserved between humans and the model archaeon Haloferax volcanii. In light of this finding we examine whether selection or mutation can explain concordant substitution patterns in the two kingdoms. Unexpectedly, we find that neither the mutation nor the selection model are sufficient to explain the observed association between nucleosomes and sequence divergence. Instead, we demonstrate that nucleosome-associated substitution patterns are more consistent with a third model where sequence divergence results in frequent repositioning of nucleosomes during evolution. Indeed, we show that nucleosome repositioning is both necessary and largely sufficient to explain the association between current nucleosome positions and biased substitution patterns. This finding highlights the importance of considering the direction of causality between genetic and epigenetic change.

  3. Three-dimensional shear-strain patterns induced by high-pressure torsion and their impact on hardness evolution

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Y.; Wang, Y.B. [School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW 2006 (Australia); Figueiredo, R.B. [Department of Metallurgical and Materials Engineering, Federal University of Minas Gerais, Belo Horizonte, MG 31270-901 (Brazil); Chang, L. [School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW 2006 (Australia); Liao, X.Z., E-mail: xiaozhou.liao@sydney.edu.au [School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW 2006 (Australia); Kawasaki, M. [Departments of Aerospace and Mechanical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089-1453 (United States); Zheng, W.L. [Shanghai Research Institute of Materials, 99 Handan Road, Shanghai 200437 (China); Ringer, S.P. [Australian Centre for Microscopy and Microanalysis, The University of Sydney, Sydney, NSW 2006 (Australia); Langdon, T.G. [Departments of Aerospace and Mechanical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089-1453 (United States); Materials Research Group, School of Engineering Sciences, University of Southampton, Southampton SO17 1BJ (United Kingdom); Zhu, Y.T. [Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695 (United States)

    2011-06-15

    Highlights: > Three-dimensional shear strain patterns were evaluated during high-pressure torsion. > Double-swirl patterns are visible on the top surfaces of discs in early stages of HPT. > Double-swirls ultimately evolve into a single swirl with increasing revolutions. > Microstructural evolution in HPT may deviate initially from rigid-body situation - Abstract: The shear strain imposed on austenite/ferrite duplex stainless steel discs at different stages of high-pressure torsion (HPT) processing was imaged in plan-view and cross-section using optical microscopy and scanning electron microscopy. The effect of the shear strain was correlated to the hardness evolution of the discs. The shear-strain patterns are complex and are different on the top and bottom surfaces of the discs. A double-swirl pattern emerged on the top surface in the early stages of HPT. These two centres of the swirl moved towards the centre of the disc as the numbers of HPT revolutions was increased and ultimately the double-swirl evolved into a single-swirl. Less regular shear-strain patterns were observed on the bottom surfaces of the discs. Multiple ring-like patterns with mirror symmetry over the central axes of the discs were visible from cross-sectional observations. Nanoindentation testing on the two surfaces and a cross-section of HPT discs showed that the hardness is insensitive to specific shear-strain patterns, but is closely related to the widths of the austenite and ferrite phase domains. Late in the deformation process, the hardness in the interior of an HPT disc may be higher than at either of the disc surfaces because of the development of finer microstructural phase distributions.

  4. Perspectives for spintronics in 2D materials

    Directory of Open Access Journals (Sweden)

    Wei Han

    2016-03-01

    Full Text Available The past decade has been especially creative for spintronics since the (rediscovery of various two dimensional (2D materials. Due to the unusual physical characteristics, 2D materials have provided new platforms to probe the spin interaction with other degrees of freedom for electrons, as well as to be used for novel spintronics applications. This review briefly presents the most important recent and ongoing research for spintronics in 2D materials.

  5. Inferring directions of evolution from patterns of variation: The legacy of Sergei Meyen

    OpenAIRE

    Sharov, Alexei A; Igamberdiev, Abir U.

    2014-01-01

    In the era of the Extended Evolutionary Synthesis, which no longer considers natural selection as the only leading factor of evolution, it is meaningful to revisit the legacy of biologists who discussed the role of alternative factors. Here we analyze the evolutionary views of Sergei Meyen (1935-1987), a paleobotanist who argued that the theory of evolution should incorporate a “nomothetical” approach which infers the laws of morphogenesis (i.e., form generation) from the obser...

  6. 2D-dynamic representation of DNA sequences as a graphical tool in bioinformatics

    Science.gov (United States)

    Bielińska-Wa̧Ż, D.; Wa̧Ż, P.

    2016-10-01

    2D-dynamic representation of DNA sequences is briefly reviewed. Some new examples of 2D-dynamic graphs which are the graphical tool of the method are shown. Using the examples of the complete genome sequences of the Zika virus it is shown that the present method can be applied for the study of the evolution of viral genomes.

  7. Models of Late-Type Disk Galaxies: 1-D Versus 2-D

    CERN Document Server

    Mineikis, Tadas

    2015-01-01

    We investigate the effects of stochasticity on the observed galaxy parameters by comparing our stochastic star formation two-dimensional (2-D) galaxy evolution models with the commonly used one-dimensional (1-D) models with smooth star formation. The 2-D stochastic models predict high variability of the star formation rate and the surface photometric parameters across the galactic disks and in time.

  8. Correlated evolution of life-history with size at maturity in Daphnia pulicaria: patterns within and between populations.

    Science.gov (United States)

    Baer, Charles F; Lynch, Michael

    2003-04-01

    Explaining the repeated evolution of similar sets of traits under similar environmental conditions is an important issue in evolutionary biology. The extreme alternative classes of explanations for correlated suites of traits are optimal adaptation and genetic constraint resulting from pleiotropy. Adaptive explanations presume that individual traits are free to evolve to their local optima and that convergent evolution represents particularly adaptive combinations of traits. Alternatively, if pleiotropy is strong and difficult to break, strong selection on one or a few particularly important characters would be expected to result in consistent correlated evolution of associated traits. If pleiotropy is common, we predict that the pattern of divergence among populations will consistently reflect the within-population genetic architecture. To test the idea that the multivariate life-history phenotype is largely a byproduct of strong selection on body size, we imposed divergent artificial selection on size at maturity upon two populations of the cladoceran Daphnia pulicaria, chosen on the basis of their extreme divergence in body size. Overall, the trajectory of divergence between the two natural populations did not differ from that predicted by the genetic architecture within each population. However, the pattern of correlated responses suggested the presence of strong pleiotropic constraints only for adult body size and not for other life-history traits. One trait, offspring size, appears to have evolved in a way different from that expected from the within-population genetic architecture and may be under stabilizing selection.

  9. Annotated Bibliography of EDGE2D Use

    Energy Technology Data Exchange (ETDEWEB)

    J.D. Strachan and G. Corrigan

    2005-06-24

    This annotated bibliography is intended to help EDGE2D users, and particularly new users, find existing published literature that has used EDGE2D. Our idea is that a person can find existing studies which may relate to his intended use, as well as gain ideas about other possible applications by scanning the attached tables.

  10. Port Adriano, 2D-Model Tests

    DEFF Research Database (Denmark)

    Burcharth, Hans F.; Andersen, Thomas Lykke; Jensen, Palle Meinert

    This report present the results of 2D physical model tests (length scale 1:50) carried out in a waveflume at Dept. of Civil Engineering, Aalborg University (AAU).......This report present the results of 2D physical model tests (length scale 1:50) carried out in a waveflume at Dept. of Civil Engineering, Aalborg University (AAU)....

  11. Implementation of 2D Discrete Wavelet Transform by Number Theoretic Transform and 2D Overlap-Save Method

    Directory of Open Access Journals (Sweden)

    Lina Yang

    2014-01-01

    Full Text Available To reduce the computation complexity of wavelet transform, this paper presents a novel approach to be implemented. It consists of two key techniques: (1 fast number theoretic transform(FNTT In the FNTT, linear convolution is replaced by the circular one. It can speed up the computation of 2D discrete wavelet transform. (2 In two-dimensional overlap-save method directly calculating the FNTT to the whole input sequence may meet two difficulties; namely, a big modulo obstructs the effective implementation of the FNTT and a long input sequence slows the computation of the FNTT down. To fight with such deficiencies, a new technique which is referred to as 2D overlap-save method is developed. Experiments have been conducted. The fast number theoretic transform and 2D overlap-method have been used to implement the dyadic wavelet transform and applied to contour extraction in pattern recognition.

  12. Evolution of aging: individual life history trade-offs and population heterogeneity account for mortality patterns across species.

    Science.gov (United States)

    Le Cunff, Y; Baudisch, A; Pakdaman, K

    2014-08-01

    A broad range of mortality patterns has been documented across species, some even including decreasing mortality over age. Whether there exist a common denominator to explain both similarities and differences in these mortality patterns remains an open question. The disposable soma theory, an evolutionary theory of aging, proposes that universal intracellular trade-offs between maintenance/lifespan and reproduction would drive aging across species. The disposable soma theory has provided numerous insights concerning aging processes in single individuals. Yet, which specific population mortality patterns it can lead to is still largely unexplored. In this article, we propose a model exploring the mortality patterns which emerge from an evolutionary process including only the disposable soma theory core principles. We adapt a well-known model of genomic evolution to show that mortality curves producing a kink or mid-life plateaus derive from a common minimal evolutionary framework. These mortality shapes qualitatively correspond to those of Drosophila melanogaster, Caenorhabditis elegans, medflies, yeasts and humans. Species evolved in silico especially differ in their population diversity of maintenance strategies, which itself emerges as an adaptation to the environment over generations. Based on this integrative framework, we also derive predictions and interpretations concerning the effects of diet changes and heat-shock treatments on mortality patterns.

  13. Unbounded growth patterns of reproducing, competing polymers—similarities to biological evolution

    Science.gov (United States)

    Gregor Worst, Emanuel; Zimmer, Philipp; Wollrab, Eva; Kruse, Karsten; Ott, Albrecht

    2016-10-01

    Since the origin of life the interplay between reproduction, variation, and selection has been driving the emergence of new species. The evolution of the Earth’s biosphere appears to innovate unceasingly instead of coming to a stall. Here, we introduce a model system of linear molecules where new polymers appear by spontaneous ligation. The polymers proliferate following a template-based mechanism. Our combined experimental and theoretical study shows that for sufficiently rapid autocatalysis the reproduction process selects particular lengths—while ever longer polymers emerge. We suggest similarities to biological evolution.

  14. Implications of the evolution pattern of human T-cell leukemia retroviruses on their pathogenic virulence (Review).

    Science.gov (United States)

    Azran, Inbal; Schavinsky-Khrapunsky, Yana; Priel, Esther; Huleihel, Mahmoud; Aboud, Mordechai

    2004-11-01

    Simian retroviruses pose a serious threat to public health, as two human pathogenic retroviruses, HIV and HTLV, have been already proved to originate from such non-human viruses. Therefore, studying their natural prevalence among wild non-human primates is important for planning strategies to prevent the emergence of additional human retroviral pathogens. This article is focused on tracing the origin and evolution of the human T-cell leukemia viruses HTLV-I and HTLV-II in comparison to that of the simian lymphotropic viruses STLV-I, STLV-II and STLV-L, which are phylo-genically classified into a common group called primate T-lymphotropic viruses (PTLV). Thus, HTLV-I and STLV-I are referred to as PTLV-I and HTLV-II and STLV-II as PTLV-II, whereas STLV-L, which is highly divergent from both HTLV types, comprises a third subgroup called PTLV-L. The phylogeny of PTLV indicates that both, HTLV-I and HTLV-II emerged from a simian origin, but their subsequent evolution continued in different patterns. HTLV-I includes 6 subtypes which evolved from STLV-I through several times of different geographic interspecies transmission between simian and human hosts. These repeated invasions to new primate species are likely to give rise to viral strains with increasing pathogenic potential. On the other hand, HTLV-II includes 4 subtypes which appear to originate from a common human ancestor virus that emerged from only one simian to human transmission, whereas the subsequent evolution of HTLV-II and STLV-II strains continued separately only within the Homo sapiens and Pan paniscus species respectively, without repeated interspecies jumps. Such evolution pattern likely involves less genetic changes and selection of viral strains with low pathogenic virulence that could co-exist with their hosts for long time. These different evolution patterns can explain the much wider implication of HTLV-I with human clinical disorders than HTLV-II. Of note, however, more recently HTLV-II started

  15. Pigment pattern evolution by differential deployment of neural crest and post-embryonic melanophore lineages in Danio fishes.

    Science.gov (United States)

    Quigley, Ian K; Turner, Jessica M; Nuckels, Richard J; Manuel, Joan L; Budi, Erine H; MacDonald, Erin L; Parichy, David M

    2004-12-01

    Latent precursors or stem cells of neural crest origin are present in a variety of post-embryonic tissues. Although these cells are of biomedical interest for roles in human health and disease, their potential evolutionary significance has been underappreciated. As a first step towards elucidating the contributions of such cells to the evolution of vertebrate form, we investigated the relative roles of neural crest cells and post-embryonic latent precursors during the evolutionary diversification of adult pigment patterns in Danio fishes. These pigment patterns result from the numbers and arrangements of embryonic melanophores that are derived from embryonic neural crest cells, as well as from post-embryonic metamorphic melanophores that are derived from latent precursors of presumptive neural crest origin. In the zebrafish D. rerio, a pattern of melanophore stripes arises during the larval-to-adult transformation by the recruitment of metamorphic melanophores from latent precursors. Using a comparative approach in the context of new phylogenetic data, we show that adult pigment patterns in five additional species also arise from metamorphic melanophores, identifying this as an ancestral mode of adult pigment pattern development. By contrast, superficially similar adult stripes of D. nigrofasciatus (a sister species to D. rerio) arise by the reorganization of melanophores that differentiated at embryonic stages, with a diminished contribution from metamorphic melanophores. Genetic mosaic and molecular marker analyses reveal evolutionary changes that are extrinsic to D. nigrofasciatus melanophore lineages, including a dramatic reduction of metamorphic melanophore precursors. Finally, interspecific complementation tests identify a candidate genetic pathway for contributing to the evolutionary reduction in metamorphic melanophores and the increased contribution of early larval melanophores to D. nigrofasciatus adult pigment pattern development. These results

  16. The Pattern and Evolution of the Permian Palaeobiogeography and Tectonic Palaeogeography in Jilin and Heilongjiang Orogenic Belt

    Institute of Scientific and Technical Information of China (English)

    Peng Xiangdong; Li Xiaomin; Liu Pengju

    2000-01-01

    The orogenic belt locates between the North China plate and Siberia plate. The Permian palaeobiogeography and tectonic palaeogeography changed quickly and clearly. The line from Changchun to Yanji is an important palaeobiogeographic provincing line, which may be the collission suture belt of the North China plate and north middle massifs. The orogenic belt has been divided into 2 regions: the North middle massif region and the North Margin of North China plate, the pattern and evolution of Permian palaeobiogeography in the present area were discussed and the Permian biota mixture and its significants were analysed. Then, Based on the above, the Permian tectonic palaeogeography of the orogenic belt is reconstructed.

  17. 2D materials for nanophotonic devices

    Science.gov (United States)

    Xu, Renjing; Yang, Jiong; Zhang, Shuang; Pei, Jiajie; Lu, Yuerui

    2015-12-01

    Two-dimensional (2D) materials have become very important building blocks for electronic, photonic, and phononic devices. The 2D material family has four key members, including the metallic graphene, transition metal dichalcogenide (TMD) layered semiconductors, semiconducting black phosphorous, and the insulating h-BN. Owing to the strong quantum confinements and defect-free surfaces, these atomically thin layers have offered us perfect platforms to investigate the interactions among photons, electrons and phonons. The unique interactions in these 2D materials are very important for both scientific research and application engineering. In this talk, I would like to briefly summarize and highlight the key findings, opportunities and challenges in this field. Next, I will introduce/highlight our recent achievements. We demonstrated atomically thin micro-lens and gratings using 2D MoS2, which is the thinnest optical component around the world. These devices are based on our discovery that the elastic light-matter interactions in highindex 2D materials is very strong. Also, I would like to introduce a new two-dimensional material phosphorene. Phosphorene has strongly anisotropic optical response, which creates 1D excitons in a 2D system. The strong confinement in phosphorene also enables the ultra-high trion (charged exciton) binding energies, which have been successfully measured in our experiments. Finally, I will briefly talk about the potential applications of 2D materials in energy harvesting.

  18. Shaped Beam Pattern Synthesis of Antenna Arrays Using Composite Differential Evolution with Eigenvector-Based Crossover Operator

    Directory of Open Access Journals (Sweden)

    Sotirios K. Goudos

    2015-01-01

    Full Text Available This paper addresses the problem of designing shaped beam patterns with arbitrary arrays subject to constraints. The constraints could include the sidelobe level suppression in specified angular intervals, the mainlobe halfpower beamwidth, and the predefined number of elements. In this paper, we propose a new Differential Evolution algorithm, which combines Composite DE with an eigenvector-based crossover operator (CODE-EIG. This operator utilizes eigenvectors of covariance matrix of individual solutions, which makes the crossover rotationally invariant. We apply this novel design method to shaped beam pattern synthesis for linear and conformal arrays. We compare this algorithm with other popular algorithms and DE variants. The results show CODE-EIG outperforms the other DE algorithms in terms of statistical results and convergence speed.

  19. The evolution of colour pattern complexity: selection for conspicuousness favours contrasting within-body colour combinations in lizards.

    Science.gov (United States)

    Pérez I de Lanuza, G; Font, E

    2016-05-01

    Many animals display complex colour patterns that comprise several adjacent, often contrasting colour patches. Combining patches of complementary colours increases the overall conspicuousness of the complex pattern, enhancing signal detection. Therefore, selection for conspicuousness may act not only on the design of single colour patches, but also on their combination. Contrasting long- and short-wavelength colour patches are located on the ventral and lateral surfaces of many lacertid lizards. As the combination of long- and short-wavelength-based colours generates local chromatic contrast, we hypothesized that selection may favour the co-occurrence of lateral and ventral contrasting patches, resulting in complex colour patterns that maximize the overall conspicuousness of the signal. To test this hypothesis, we performed a comparative phylogenetic study using a categorical colour classification based on spectral data and descriptive information on lacertid coloration collected from the literature. Our results demonstrate that conspicuous ventral (long-wavelength-based) and lateral (short-wavelength-based) colour patches co-occur throughout the lacertid phylogeny more often than expected by chance, especially in the subfamily Lacertini. These results suggest that selection promotes the evolution of the complex pattern rather than the acquisition of a single conspicuous colour patch, possibly due to the increased conspicuousness caused by the combination of colours with contrasting spectral properties.

  20. Patterns of maximum body size evolution in Cenozoic land mammals: eco-evolutionary processes and abiotic forcing

    Science.gov (United States)

    Saarinen, Juha J.; Boyer, Alison G.; Brown, James H.; Costa, Daniel P.; Ernest, S. K. Morgan; Evans, Alistair R.; Fortelius, Mikael; Gittleman, John L.; Hamilton, Marcus J.; Harding, Larisa E.; Lintulaakso, Kari; Lyons, S. Kathleen; Okie, Jordan G.; Sibly, Richard M.; Stephens, Patrick R.; Theodor, Jessica; Uhen, Mark D.; Smith, Felisa A.

    2014-01-01

    There is accumulating evidence that macroevolutionary patterns of mammal evolution during the Cenozoic follow similar trajectories on different continents. This would suggest that such patterns are strongly determined by global abiotic factors, such as climate, or by basic eco-evolutionary processes such as filling of niches by specialization. The similarity of pattern would be expected to extend to the history of individual clades. Here, we investigate the temporal distribution of maximum size observed within individual orders globally and on separate continents. While the maximum size of individual orders of large land mammals show differences and comprise several families, the times at which orders reach their maximum size over time show strong congruence, peaking in the Middle Eocene, the Oligocene and the Plio-Pleistocene. The Eocene peak occurs when global temperature and land mammal diversity are high and is best explained as a result of niche expansion rather than abiotic forcing. Since the Eocene, there is a significant correlation between maximum size frequency and global temperature proxy. The Oligocene peak is not statistically significant and may in part be due to sampling issues. The peak in the Plio-Pleistocene occurs when global temperature and land mammal diversity are low, it is statistically the most robust one and it is best explained by global cooling. We conclude that the macroevolutionary patterns observed are a result of the interplay between eco-evolutionary processes and abiotic forcing. PMID:24741007

  1. Patterns of maximum body size evolution in Cenozoic land mammals: eco-evolutionary processes and abiotic forcing.

    Science.gov (United States)

    Saarinen, Juha J; Boyer, Alison G; Brown, James H; Costa, Daniel P; Ernest, S K Morgan; Evans, Alistair R; Fortelius, Mikael; Gittleman, John L; Hamilton, Marcus J; Harding, Larisa E; Lintulaakso, Kari; Lyons, S Kathleen; Okie, Jordan G; Sibly, Richard M; Stephens, Patrick R; Theodor, Jessica; Uhen, Mark D; Smith, Felisa A

    2014-06-07

    There is accumulating evidence that macroevolutionary patterns of mammal evolution during the Cenozoic follow similar trajectories on different continents. This would suggest that such patterns are strongly determined by global abiotic factors, such as climate, or by basic eco-evolutionary processes such as filling of niches by specialization. The similarity of pattern would be expected to extend to the history of individual clades. Here, we investigate the temporal distribution of maximum size observed within individual orders globally and on separate continents. While the maximum size of individual orders of large land mammals show differences and comprise several families, the times at which orders reach their maximum size over time show strong congruence, peaking in the Middle Eocene, the Oligocene and the Plio-Pleistocene. The Eocene peak occurs when global temperature and land mammal diversity are high and is best explained as a result of niche expansion rather than abiotic forcing. Since the Eocene, there is a significant correlation between maximum size frequency and global temperature proxy. The Oligocene peak is not statistically significant and may in part be due to sampling issues. The peak in the Plio-Pleistocene occurs when global temperature and land mammal diversity are low, it is statistically the most robust one and it is best explained by global cooling. We conclude that the macroevolutionary patterns observed are a result of the interplay between eco-evolutionary processes and abiotic forcing.

  2. Temporal and spatial evolution characteristics of gas-liquid two-phase flow pattern based on image texture spectrum descriptor

    Institute of Scientific and Technical Information of China (English)

    ZHOU Xi-guo; JIN Ning-de; WANG Zhen-ya; ZHANG Wen-yin

    2009-01-01

    The dynamic image information of typical gas-liquid two-phase flow patterns in vertical upward pipe is captured by a high-speed dynamic camera. The texture spectrum descriptor is used to describe the texture characteristics of the processed images whose content is represented in the form of texture spectrum histogram, and four time-varying characteristic param-eter indexes which represent image texture structure of different flow patterns are extracted. The study results show that the amplitude fluctuation of texture characteristic parameter indexes of bubble flow is lowest and shows very random complex dynamic behavior; the amplitude fluctuation of slug flow is higher and shows intermittent motion behavior between gas slug and liquid slug, and the amplitude fluctuation of churn flow is the highest and shows better periodicity; the amplitude fluctuation of bubble-slug flow is from low to high and oscillating frequence is higher than that of slug flow, and includes the features of both slug flow and bubble flow; the slug-churn flow loses the periodicity of slug flow and churn flow, and the amplitude fluctuation is high. The results indicate that the image texture characteristic parameter indexes of different flow pattern can reflect the flow characteristics of gas-liquid two-phase flow, which provides a new approach to tmderstand the temporal and spatial evolution of flow pattern dynamics.

  3. Evolution of Courtship Songs in Xenopus : Vocal Pattern Generation and Sound Production.

    Science.gov (United States)

    Leininger, Elizabeth C; Kelley, Darcy B

    2015-01-01

    The extant species of African clawed frogs (Xenopus and Silurana) provide an opportunity to link the evolution of vocal characters to changes in the responsible cellular and molecular mechanisms. In this review, we integrate several robust lines of research: evolutionary trajectories of Xenopus vocalizations, cellular and circuit-level mechanisms of vocalization in selected Xenopus model species, and Xenopus evolutionary history and speciation mechanisms. Integrating recent findings allows us to generate and test specific hypotheses about the evolution of Xenopus vocal circuits. We propose that reduced vocal sex differences in some Xenopus species result from species-specific losses of sexually differentiated neural and neuromuscular features. Modification of sex-hormone-regulated developmental mechanisms is a strong candidate mechanism for reduced vocal sex differences.

  4. Patterns of vertebrate isochore evolution revealed by comparison of expressed mammalian, avian, and crocodilian genes.

    Science.gov (United States)

    Chojnowski, Jena L; Franklin, James; Katsu, Yoshinao; Iguchi, Taisen; Guillette, Louis J; Kimball, Rebecca T; Braun, Edward L

    2007-09-01

    Vertebrate genomes are mosaics of isochores, defined as long (>100 kb) regions with relatively homogeneous within-region base composition. Birds and mammals have more GC-rich isochores than amphibians and fish, and the GC-rich isochores of birds and mammals have been suggested to be an adaptation to homeothermy. If this hypothesis is correct, all poikilothermic (cold-blooded) vertebrates, including the nonavian reptiles, are expected to lack a GC-rich isochore structure. Previous studies using various methods to examine isochore structure in crocodilians, turtles, and squamates have led to different conclusions. We collected more than 6000 expressed sequence tags (ESTs) from the American alligator to overcome sample size limitations suggested to be the fundamental problem in the previous reptilian studies. The alligator ESTs were assembled and aligned with their human, mouse, chicken, and western clawed frog orthologs, resulting in 366 alignments. Analyses of third-codon-position GC content provided conclusive evidence that the poikilothermic alligator has GC-rich isochores, like homeothermic birds and mammals. We placed these results in a theoretical framework able to unify available models of isochore evolution. The data collected for this study allowed us to reject the models that explain the evolution of GC content using changes in body temperature associated with the transition from poikilothermy to homeothermy. Falsification of these models places fundamental constraints upon the plausible pathways for the evolution of isochores.

  5. An Analysis of Evolution of Lending Patterns of IFAD China’s Rural Financial Project

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    This paper tells us briefly the background and aims of the fundation of IFAD.It points out that IFAD plays an important part in helping the development of agriculture and food production in developing countries,and in reducing the poverty conditions in the poorest countries.It tells us that IFAD has offered donation to China for 8 times,with a total amount reaching to 56.839 million dollars.With the development of the economy of China,IFAD has changed its lending financial policies to China from a highly beneficial policy to a moderate lending policy.The operation of the loan projects have greatly improved the living conditions and of the local and the conditions of agricultural production,promoting the improvement of economy,social stability,and enviroment.It discusses several lending patterns of IFAD China’s rural financial projects.The government-leading model,which is represented by the IFAD financial lending loan.Market-oriented model of formal financial institutions,which is represented by IFAD Rural Credit Cooperatives,with market oriented.Government supporting as secondary model,which are dominated by IFAD Women’s lending patterns and Village Development Fund lending model.In this paper,advantages and disadvantages of lending patterns are analyzed and evaluated.It discusses the development trend of IFAD financial lending patterns in terms of Rural Credit Cooperatives and a pattern which is community-oriented and farmers-benefited.

  6. Bees, birds and yellow flowers: pollinator-dependent convergent evolution of UV patterns.

    Science.gov (United States)

    Papiorek, S; Junker, R R; Alves-Dos-Santos, I; Melo, G A R; Amaral-Neto, L P; Sazima, M; Wolowski, M; Freitas, L; Lunau, K

    2016-01-01

    Colour is one of the most obvious advertisements of flowers, and occurs in a huge diversity among the angiosperms. Flower colour is responsible for attraction from a distance, whereas contrasting colour patterns within flowers aid orientation of flower visitors after approaching the flowers. Due to the striking differences in colour vision systems and neural processing across animal taxa, flower colours evoke specific behavioural responses by different flower visitors. We tested whether and how yellow flowers differ in their spectral reflectance depending on the main pollinator. We focused on bees and birds and examined whether the presence or absence of the widespread UV reflectance pattern of yellow flowers predicts the main pollinator. Most bee-pollinated flowers displayed a pattern with UV-absorbing centres and UV-reflecting peripheries, whereas the majority of bird-pollinated flowers are entirely UV- absorbing. In choice experiments we found that bees did not show consistent preferences for any colour or pattern types. However, all tested bee species made their first antennal contact preferably at the UV-absorbing area of the artificial flower, irrespective of its spatial position within the flower. The appearance of UV patterns within flowers is the main difference in spectral reflectance between yellow bee- and bird-pollinated flowers, and affects the foraging behaviour of flower visitors. The results support the hypothesis that flower colours and the visual capabilities of their efficient pollinators are adapted to each other.

  7. Multi-Input Single Output SSSC based damping controller design by a hybrid Improved Differential Evolution-Pattern Search approach.

    Science.gov (United States)

    Panda, Sidhartha; Yegireddy, Narendra Kumar

    2015-09-01

    In this paper, a hybrid Improved Differential Evolution and Pattern Search (hIDEPS) approach is proposed for the design of a PI-Type Multi-Input Single Output (MISO) Static Synchronous Series Compensator (SSSC) based damping controller. The improvement in Differential Evolution (DE) algorithm is introduced by a simple but effective scheme of changing two of its most important control parameters i.e. step size and crossover probability with an objective of achieving improved performance. Pattern Search (PS) is subsequently employed to fine tune the best solution provided by modified DE algorithm. The superiority of a proposed hIDEPS technique over DE and improved DE has also been demonstrated. At the outset, this concept is applied to a SSSC connected in a Single Machine Infinite Bus (SMIB) power system and then extended to a multi-machine power system. To show the effectiveness and robustness of the proposed design approach, simulation results are presented and compared with DE and Particle Swarm Optimization (PSO) optimized Single Input Single Output (SISO) SSSC based damping controllers. It is observed that the proposed approach yield superior damping performance compared to some approaches available in the literature.

  8. DNA aneuploidy as a topographic malignant transformation pattern in a pleomorphic adenoma of long-term evolution: a case report

    Directory of Open Access Journals (Sweden)

    Gallego Lorena

    2011-11-01

    Full Text Available Abstract Introduction We present a case of long-term evolution of a submandibular pleomorphic adenoma. There is little information about topographic malignant transformation patterns of pleomorphic adenomas. Case presentation We extensively analyze a giant submandibular mixed tumor of 25-year evolution in a 57-year-old Caucasian woman. Deoxyribonucleic acid ploidy was evaluated in different superficial and deep areas using flow cytometry analysis and correlated with pathological and immunohistochemical characteristics. Superficial areas exhibited a typical histological pleomorphic adenoma pattern and were deoxyribonucleic acid diploid. Deep samples showed deoxyribonucleic acid aneuploidy, atypical histological benign features and expression of markers involved at an early-stage of malignant transformation, such as tumor protein 53 and antigen Ki67. Conclusion These findings revealed that deep tumor compartments may be involved in the initial stages of malignant transformation. Deoxyribonucleic acid ploidy analysis may provide an additional diagnosis tool and indicate 'uncertain' areas that require careful study to avoid diagnostic errors. Larger studies are needed to confirm our results and to evaluate the usefulness of the technique.

  9. 2D/3D switchable displays

    Science.gov (United States)

    Dekker, T.; de Zwart, S. T.; Willemsen, O. H.; Hiddink, M. G. H.; IJzerman, W. L.

    2006-02-01

    A prerequisite for a wide market acceptance of 3D displays is the ability to switch between 3D and full resolution 2D. In this paper we present a robust and cost effective concept for an auto-stereoscopic switchable 2D/3D display. The display is based on an LCD panel, equipped with switchable LC-filled lenticular lenses. We will discuss 3D image quality, with the focus on display uniformity. We show that slanting the lenticulars in combination with a good lens design can minimize non-uniformities in our 20" 2D/3D monitors. Furthermore, we introduce fractional viewing systems as a very robust concept to further improve uniformity in the case slanting the lenticulars and optimizing the lens design are not sufficient. We will discuss measurements and numerical simulations of the key optical characteristics of this display. Finally, we discuss 2D image quality, the switching characteristics and the residual lens effect.

  10. Matrix models of 2d gravity

    Energy Technology Data Exchange (ETDEWEB)

    Ginsparg, P.

    1991-01-01

    These are introductory lectures for a general audience that give an overview of the subject of matrix models and their application to random surfaces, 2d gravity, and string theory. They are intentionally 1.5 years out of date.

  11. Matrix models of 2d gravity

    Energy Technology Data Exchange (ETDEWEB)

    Ginsparg, P.

    1991-12-31

    These are introductory lectures for a general audience that give an overview of the subject of matrix models and their application to random surfaces, 2d gravity, and string theory. They are intentionally 1.5 years out of date.

  12. Applications of 2D helical vortex dynamics

    DEFF Research Database (Denmark)

    Okulov, Valery; Sørensen, Jens Nørkær

    2010-01-01

    In the paper, we show how the assumption of helical symmetry in the context of 2D helical vortices can be exploited to analyse and to model various cases of rotating flows. From theory, examples of three basic applications of 2D dynamics of helical vortices embedded in flows with helical symmetry...... of the vorticity field are addressed. These included some of the problems related to vortex breakdown, instability of far wakes behind rotors and vortex theory of ideal rotors....

  13. 2D Saturable Absorbers for Fibre Lasers

    Directory of Open Access Journals (Sweden)

    Robert I. Woodward

    2015-11-01

    Full Text Available Two-dimensional (2D nanomaterials are an emergent and promising platform for future photonic and optoelectronic applications. Here, we review recent progress demonstrating the application of 2D nanomaterials as versatile, wideband saturable absorbers for Q-switching and mode-locking fibre lasers. We focus specifically on the family of few-layer transition metal dichalcogenides, including MoS2, MoSe2 and WS2.

  14. Image processing of 2D crystal images.

    Science.gov (United States)

    Arheit, Marcel; Castaño-Díez, Daniel; Thierry, Raphaël; Gipson, Bryant R; Zeng, Xiangyan; Stahlberg, Henning

    2013-01-01

    Electron crystallography of membrane proteins uses cryo-transmission electron microscopy to image frozen-hydrated 2D crystals. The processing of recorded images exploits the periodic arrangement of the structures in the images to extract the amplitudes and phases of diffraction spots in Fourier space. However, image imperfections require a crystal unbending procedure to be applied to the image before evaluation in Fourier space. We here describe the process of 2D crystal image unbending, using the 2dx software system.

  15. Domestication and the mitochondrial genome: comparing patterns and rates of molecular evolution in domesticated mammals and birds and their wild relatives.

    Science.gov (United States)

    Moray, Camile; Lanfear, Robert; Bromham, Lindell

    2014-01-01

    Studies of domesticated animals have led to the suggestion that domestication could have significant effects on patterns of molecular evolution. In particular, analyses of mitochondrial genome sequences from domestic dogs and yaks have yielded higher ratios of non-synonymous to synonymous substitutions in the domesticated lineages than in their wild relatives. These results are important because they imply that changes to selection or population size operating over a short timescale can cause significant changes to the patterns of mitochondrial molecular evolution. In this study, our aim is to test whether the impact on mitochondrial genome evolution is a general feature of domestication or whether it is specific to particular examples. We test whether domesticated mammals and birds have consistently different patterns of molecular evolution than their wild relatives for 16 phylogenetically independent comparisons of mitochondrial genome sequences. We find no consistent difference in branch lengths or dN/dS between domesticated and wild lineages. We also find no evidence that our failure to detect a consistent pattern is due to the short timescales involved or low genetic distance between domesticated lineages and their wild relatives. However, removing comparisons where the wild relative may also have undergone a bottleneck does reveal a pattern consistent with reduced effective population size in domesticated lineages. Our results suggest that, although some domesticated lineages may have undergone changes to selective regime or effective population size that could have affected mitochondrial evolution, it is not possible to generalize these patterns over all domesticated mammals and birds.

  16. Variation in the Intensity of Selection on Codon Bias over Time Causes Contrasting Patterns of Base Composition Evolution in Drosophila

    Science.gov (United States)

    Jackson, Benjamin C.; Campos, José L.; Haddrill, Penelope R.; Charlesworth, Brian

    2017-01-01

    Four-fold degenerate coding sites form a major component of the genome, and are often used to make inferences about selection and demography, so that understanding their evolution is important. Despite previous efforts, many questions regarding the causes of base composition changes at these sites in Drosophila remain unanswered. To shed further light on this issue, we obtained a new whole-genome polymorphism data set from D. simulans. We analyzed samples from the putatively ancestral range of D. simulans, as well as an existing polymorphism data set from an African population of D. melanogaster. By using D. yakuba as an outgroup, we found clear evidence for selection on 4-fold sites along both lineages over a substantial period, with the intensity of selection increasing with GC content. Based on an explicit model of base composition evolution, we suggest that the observed AT-biased substitution pattern in both lineages is probably due to an ancestral reduction in selection intensity, and is unlikely to be the result of an increase in mutational bias towards AT alone. By using two polymorphism-based methods for estimating selection coefficients over different timescales, we show that the selection intensity on codon usage has been rather stable in D. simulans in the recent past, but the long-term estimates in D. melanogaster are much higher than the short-term ones, indicating a continuing decline in selection intensity, to such an extent that the short-term estimates suggest that selection is only active in the most GC-rich parts of the genome. Finally, we provide evidence for complex evolutionary patterns in the putatively neutral short introns, which cannot be explained by the standard GC-biased gene conversion model. These results reveal a dynamic picture of base composition evolution. PMID:28082609

  17. 2d index and surface operators

    Science.gov (United States)

    Gadde, Abhijit; Gukov, Sergei

    2014-03-01

    In this paper we compute the superconformal index of 2d (2, 2) supersymmetric gauge theories. The 2d superconformal index, a.k.a. flavored elliptic genus, is computed by a unitary matrix integral much like the matrix integral that computes the 4d superconformal index. We compute the 2d index explicitly for a number of examples. In the case of abelian gauge theories we see that the index is invariant under flop transition and under CY-LG correspondence. The index also provides a powerful check of the Seiberg-type duality for non-abelian gauge theories discovered by Hori and Tong. In the later half of the paper, we study half-BPS surface operators in = 2 super-conformal gauge theories. They are engineered by coupling the 2d (2, 2) supersymmetric gauge theory living on the support of the surface operator to the 4d = 2 theory, so that different realizations of the same surface operator with a given Levi type are related by a 2d analogue of the Seiberg duality. The index of this coupled system is computed by using the tools developed in the first half of the paper. The superconformal index in the presence of surface defect is expected to be invariant under generalized S-duality. We demonstrate that it is indeed the case. In doing so the Seiberg-type duality of the 2d theory plays an important role.

  18. Glitter in a 2D monolayer.

    Science.gov (United States)

    Yang, Li-Ming; Dornfeld, Matthew; Frauenheim, Thomas; Ganz, Eric

    2015-10-21

    We predict a highly stable and robust atomically thin gold monolayer with a hexagonal close packed lattice stabilized by metallic bonding with contributions from strong relativistic effects and aurophilic interactions. We have shown that the framework of the Au monolayer can survive 10 ps MD annealing simulations up to 1400 K. The framework is also able to survive large motions out of the plane. Due to the smaller number of bonds per atom in the 2D layer compared to the 3D bulk we observe significantly enhanced energy per bond (0.94 vs. 0.52 eV per bond). This is similar to the increase in bond strength going from 3D diamond to 2D graphene. It is a non-magnetic metal, and was found to be the global minima in the 2D space. Phonon dispersion calculations demonstrate high kinetic stability with no negative modes. This 2D gold monolayer corresponds to the top monolayer of the bulk Au(111) face-centered cubic lattice. The close-packed lattice maximizes the aurophilic interactions. We find that the electrons are completely delocalized in the plane and behave as 2D nearly free electron gas. We hope that the present work can inspire the experimental fabrication of novel free standing 2D metal systems.

  19. Abd-B expression in Porcellio scaber Latreille, 1804 (Isopoda: Crustacea): conserved pattern versus novel roles in development and evolution.

    Science.gov (United States)

    Brena, C; Liu, P Z; Minelli, A; Kaufman, T C

    2005-01-01

    The Hox genes are intimately involved in patterning the animal body during development and are considered to have had a pivotal role in the evolution of different body plans among the metazoans. From this perspective, crustaceans, a group that has evolved an extreme diversity of body structures, represent a choice group in which to study the evolution of these genes and their expression. The expression of one of these genes, Abdominal-B (Abd-B), has only been studied in two distantly related crustaceans, Artemia and Sacculina, where it shows dissimilar patterns, highly differentiated from the one described in other arthropods. Moreover, we have no information for the Malacostraca. Thus, we cloned the gene Abd-B and followed its expression through development by in situ hybridization in the isopod Porcellio scaber. We found a highly dynamic expression pattern of PsAbd-B during embryonic development. In early stages, it is expressed in the posterior-most part of the germ band, in a domain common to several arthropods studied to date, and later it is expressed in the developing limb buds of the pleon and still later in the endopodites of the third to fifth pleopodites. This raises the interesting possibility of the involvement of this gene in the later respiratory specialization of these appendages. In association with the above expression domain, Abd-B appears to be expressed in later stages also in the ventral ectoderm, raising the further suggestion of its possible involvement in patterning the developing nervous system. Moreover, we show that the first pleopod and the endopodite of the second pleopod, whereas present as limb buds in early embryonic stages, are later reduced and actually absent in the first postembryonic stage, although they reappear again in adults. These appendages thus represent an example of Lazarus appendages. Our data show strong plasticity in the use of a key developmental gene and point out the necessity of further research that may end

  20. 2-D DOA Estimation Based on 2D-MUSIC%基于2D-MUSIC算法的DOA估计

    Institute of Scientific and Technical Information of China (English)

    康亚芳; 王静; 张清泉; 行小帅

    2014-01-01

    This paper discussed the performance of classical two-dimensional DOA estimation with 2D-MUSIC, based on the mathematical model of planar array and 2D-MUSIC DOA estimation, Taking uniform planar array for example, comput-er simulation experiment was carried for the effect of three kinds of different parameters on 2-D DOA estimation, and the simulation results were analyzed. And also verification test about the corresponding algorithm performance under the differ-ent parameters was discussed.%利用经典的2D-MUSIC算法对二维阵列的DOA估计进行了研究,在平面阵列数学模型以及2D-MUSIC算法的DOA估计模型基础上,以均匀平面阵列为例,对3种不同参数的DOA估计进行了计算机仿真,分析了仿真结果。得出了在不同参数变化趋势下DOA估计的相应变化情况。

  1. Strain localization band width evolution by electronic speckle pattern interferometry strain rate measurement

    Energy Technology Data Exchange (ETDEWEB)

    Guelorget, Bruno [Institut Charles Delaunay-LASMIS, Universite de technologie de Troyes, FRE CNRS 2848, 12 rue Marie Curie, B.P. 2060, 10010 Troyes Cedex (France)], E-mail: bruno.guelorget@utt.fr; Francois, Manuel; Montay, Guillaume [Institut Charles Delaunay-LASMIS, Universite de technologie de Troyes, FRE CNRS 2848, 12 rue Marie Curie, B.P. 2060, 10010 Troyes Cedex (France)

    2009-04-15

    In this paper, electronic speckle pattern interferometry strain rate measurements are used to quantify the width of the strain localization band, which occurs when a sheet specimen is submitted to tension. It is shown that the width of this band decreases with increasing strain. Just before fracture, this measured width is about five times wider than the shear band and the initial sheet thickness.

  2. Evolution of stationary wave patterns in mesospheric water vapor due to climate change

    Science.gov (United States)

    Demirhan Barı, Deniz; Gabriel, Axel; Sezginer Ünal, Yurdanur

    2016-07-01

    The variability in the observed stationary wave patterns of the mesospheric water vapor (H2O) is investigated using CMIP5 RCP 4.5 and RCP 8.5 projections. The change in the vertical and meridional wave structure at northern mid- and polar latitudes associated to the zonal and meridional eddy heat fluxes is discussed by analyzing the advection of H2O due to residual wind components. The alteration in the characteristics of the stationary wave-1 pattern of the lower mesospheric H2O (up to about 75km) related to change in the projected radiative forcing is observed for the years from 2006 to 2100. Additionally the remarkable effect of the increase in global temperature on the zonal asymmetries in small-scale transient waves and parameterized gravity waves, which largely contribute to the observed stationary wave patterns of H2O in the upper mesosphere, is analyzed. For validation purposes, the derived stratospheric patterns are verified against the eddy heat fluxes and residual advection terms derived from Aura/MLS satellite data between 2004-2010 and the reference period of the CMIP5 MPI dataset (1976-2005) providing confidence in the applied method.

  3. A comparative physical map reveals the pattern of chromosomal evolution between the turkey (Meleagris gallopavo and chicken (Gallus gallus genomes

    Directory of Open Access Journals (Sweden)

    Delany Mary E

    2011-09-01

    Full Text Available Abstract Background A robust bacterial artificial chromosome (BAC-based physical map is essential for many aspects of genomics research, including an understanding of chromosome evolution, high-resolution genome mapping, marker-assisted breeding, positional cloning of genes, and quantitative trait analysis. To facilitate turkey genetics research and better understand avian genome evolution, a BAC-based integrated physical, genetic, and comparative map was developed for this important agricultural species. Results The turkey genome physical map was constructed based on 74,013 BAC fingerprints (11.9 × coverage from two independent libraries, and it was integrated with the turkey genetic map and chicken genome sequence using over 41,400 BAC assignments identified by 3,499 overgo hybridization probes along with > 43,000 BAC end sequences. The physical-comparative map consists of 74 BAC contigs, with an average contig size of 13.6 Mb. All but four of the turkey chromosomes were spanned on this map by three or fewer contigs, with 14 chromosomes spanned by a single contig and nine chromosomes spanned by two contigs. This map predicts 20 to 27 major rearrangements distinguishing turkey and chicken chromosomes, despite up to 40 million years of separate evolution between the two species. These data elucidate the chromosomal evolutionary pattern within the Phasianidae that led to the modern turkey and chicken karyotypes. The predominant rearrangement mode involves intra-chromosomal inversions, and there is a clear bias for these to result in centromere locations at or near telomeres in turkey chromosomes, in comparison to interstitial centromeres in the orthologous chicken chromosomes. Conclusion The BAC-based turkey-chicken comparative map provides novel insights into the evolution of avian genomes, a framework for assembly of turkey whole genome shotgun sequencing data, and tools for enhanced genetic improvement of these important agricultural and

  4. 2D molybdenum disulphide (2D-MoS2) modified electrodes explored towards the oxygen reduction reaction

    Science.gov (United States)

    Rowley-Neale, Samuel J.; Fearn, Jamie M.; Brownson, Dale A. C.; Smith, Graham C.; Ji, Xiaobo; Banks, Craig E.

    2016-08-01

    Two-dimensional molybdenum disulphide nanosheets (2D-MoS2) have proven to be an effective electrocatalyst, with particular attention being focused on their use towards increasing the efficiency of the reactions associated with hydrogen fuel cells. Whilst the majority of research has focused on the Hydrogen Evolution Reaction (HER), herein we explore the use of 2D-MoS2 as a potential electrocatalyst for the much less researched Oxygen Reduction Reaction (ORR). We stray from literature conventions and perform experiments in 0.1 M H2SO4 acidic electrolyte for the first time, evaluating the electrochemical performance of the ORR with 2D-MoS2 electrically wired/immobilised upon several carbon based electrodes (namely; Boron Doped Diamond (BDD), Edge Plane Pyrolytic Graphite (EPPG), Glassy Carbon (GC) and Screen-Printed Electrodes (SPE)) whilst exploring a range of 2D-MoS2 coverages/masses. Consequently, the findings of this study are highly applicable to real world fuel cell applications. We show that significant improvements in ORR activity can be achieved through the careful selection of the underlying/supporting carbon materials that electrically wire the 2D-MoS2 and utilisation of an optimal mass of 2D-MoS2. The ORR onset is observed to be reduced to ca. +0.10 V for EPPG, GC and SPEs at 2D-MoS2 (1524 ng cm-2 modification), which is far closer to Pt at +0.46 V compared to bare/unmodified EPPG, GC and SPE counterparts. This report is the first to demonstrate such beneficial electrochemical responses in acidic conditions using a 2D-MoS2 based electrocatalyst material on a carbon-based substrate (SPEs in this case). Investigation of the beneficial reaction mechanism reveals the ORR to occur via a 4 electron process in specific conditions; elsewhere a 2 electron process is observed. This work offers valuable insights for those wishing to design, fabricate and/or electrochemically test 2D-nanosheet materials towards the ORR.Two-dimensional molybdenum disulphide nanosheets

  5. Dynamics of Quantum Particles in Perturbed Parabolic 2d Potential

    Directory of Open Access Journals (Sweden)

    A.S. Mazmanishvili

    2016-11-01

    Full Text Available 2d quantum-mechanical problem of the time evolution of a particle in a quadratic potential is studied. We suppose that the center of the potential is displaced in arbitrary way in time. An analytical expression for the wave function in arbitrary instant time was built. It is shown the dynamic shift of the center of the potential doesn’t change the variance. Moreover, the system can exhibit the resonance: when the frequency of the potential perturbation approaches to the natural frequency the amplitude of the wave packet of particle is increased.

  6. The impact of shifts in marine biodiversity hotspots on patterns of range evolution: Evidence from the Holocentridae (squirrelfishes and soldierfishes).

    Science.gov (United States)

    Dornburg, Alex; Moore, Jon; Beaulieu, Jeremy M; Eytan, Ron I; Near, Thomas J

    2015-01-01

    One of the most striking biodiversity patterns is the uneven distribution of marine species richness, with species diversity in the Indo-Australian Archipelago (IAA) exceeding all other areas. However, the IAA formed fairly recently, and marine biodiversity hotspots have shifted across nearly half the globe since the Paleogene. Understanding how lineages have responded to shifting biodiversity hotspots represents a necessary historic perspective on the formation and maintenance of global marine biodiversity. Such evolutionary inferences are often challenged by a lack of fossil evidence that provide insights into historic patterns of abundance and diversity. The greatest diversity of squirrelfishes and soldierfishes (Holocentridae) is in the IAA, yet these fishes also represent some of the most numerous fossil taxa in deposits of the former West Tethyan biodiversity hotspot. We reconstruct the pattern of holocentrid range evolution using time-calibrated phylogenies that include most living species and several fossil lineages, demonstrating the importance of including fossil species as terminal taxa in ancestral area reconstructions. Holocentrids exhibit increased range fragmentation following the West Tethyan hotspot collapse. However, rather than originating within the emerging IAA hotspot, the IAA has acted as a reservoir for holocentrid diversity that originated in adjacent regions over deep evolutionary time scales.

  7. Design of Spiking Central Pattern Generators for Multiple Locomotion Gaits in Hexapod Robots by Christiansen Grammar Evolution.

    Science.gov (United States)

    Espinal, Andres; Rostro-Gonzalez, Horacio; Carpio, Martin; Guerra-Hernandez, Erick I; Ornelas-Rodriguez, Manuel; Sotelo-Figueroa, Marco

    2016-01-01

    This paper presents a method to design Spiking Central Pattern Generators (SCPGs) to achieve locomotion at different frequencies on legged robots. It is validated through embedding its designs into a Field-Programmable Gate Array (FPGA) and implemented on a real hexapod robot. The SCPGs are automatically designed by means of a Christiansen Grammar Evolution (CGE)-based methodology. The CGE performs a solution for the configuration (synaptic weights and connections) for each neuron in the SCPG. This is carried out through the indirect representation of candidate solutions that evolve to replicate a specific spike train according to a locomotion pattern (gait) by measuring the similarity between the spike trains and the SPIKE distance to lead the search to a correct configuration. By using this evolutionary approach, several SCPG design specifications can be explicitly added into the SPIKE distance-based fitness function, such as looking for Spiking Neural Networks (SNNs) with minimal connectivity or a Central Pattern Generator (CPG) able to generate different locomotion gaits only by changing the initial input stimuli. The SCPG designs have been successfully implemented on a Spartan 6 FPGA board and a real time validation on a 12 Degrees Of Freedom (DOFs) hexapod robot is presented.

  8. Origins of adult pigmentation: diversity in pigment stem cell lineages and implications for pattern evolution.

    Science.gov (United States)

    Parichy, David M; Spiewak, Jessica E

    2015-01-01

    Teleosts comprise about half of all vertebrate species and exhibit an extraordinary diversity of adult pigment patterns that function in shoaling, camouflage, and mate choice and have played important roles in speciation. Here, we review studies that have identified several distinct neural crest lineages, with distinct genetic requirements, that give rise to adult pigment cells in fishes. These lineages include post-embryonic, peripheral nerve-associated stem cells that generate black melanophores and iridescent iridophores, cells derived directly from embryonic neural crest cells that generate yellow-orange xanthophores, and bipotent stem cells that generate both melanophores and xanthophores. This complexity in adult chromatophore lineages has implications for our understanding of adult traits, melanoma, and the evolutionary diversification of pigment cell lineages and patterns.

  9. Evolution of self-organized two-dimensional patterns of nanoclusters through demixing

    Science.gov (United States)

    Choudhuri, Madhumita; Iyengar, A. N. Sekar; Datta, Alokmay; Janaki, M. S.

    2015-09-01

    A mixture of dodecanethiol-capped Au nanoparticles (AuNPs) and the amphiphilic fatty acid, stearic acid, spread as a monomolecular layer on water surface, is observed with Brewster angle microscopy (BAM) to form a two-dimensional network of AuNP clusters through demixing, at concentration of AuNPs by weight (ρ ¯)>10 % and the surface pressure (π )≥10 mN m-1 . For π =15 mN m-1 , the number of nodes (n ) remains unchanged till ˜2 hours and then changes over to a lower n state, where the pattern consists of almost perfect circles with greater in-plane thickness of the AuNP lamellae. For the higher n state the mean-square fluctuation of BAM intensity remains flat and then decays as f (ξ ) =ξ2 α with α ˜0.6 (correlated fluctuations) over the length scales of 400 μ m -6 μ m and below 6 μ m , respectively. For the lower n state the fluctuation decays almost over the entire length scale with α =0.3 , indicating emergence of aperiodicity from quasiperiodicity and a changeover to anticorrelated fluctuations. These patterns can be looked at as two distinct chaotic trajectories in the I -I' phase space of the system (I being the scattered light intensity at any position of the pattern and I' its gradient) with characteristic Lyapunov exponents.

  10. 2d Index and Surface operators

    CERN Document Server

    Gadde, Abhijit

    2013-01-01

    In this paper we compute the superconformal index of 2d (2,2) supersymmetric gauge theories. The 2d superconformal index, a.k.a. flavored elliptic genus, is computed by a unitary matrix integral much like the matrix integral that computes 4d superconformal index. We compute the 2d index explicitly for a number of examples. In the case of abelian gauge theories we see that the index is invariant under flop transition and CY-LG correspondence. The index also provides a powerful check of the Seiberg-type duality for non-abelian gauge theories discovered by Hori and Tong. In the later half of the paper, we study half-BPS surface operators in N=2 superconformal gauge theories. They are engineered by coupling the 2d (2,2) supersymmetric gauge theory living on the support of the surface operator to the 4d N=2 theory, so that different realizations of the same surface operator with a given Levi type are related by a 2d analogue of the Seiberg duality. The index of this coupled system is computed by using the tools de...

  11. Homoplasy: from detecting pattern to determining process and mechanism of evolution.

    Science.gov (United States)

    Wake, David B; Wake, Marvalee H; Specht, Chelsea D

    2011-02-25

    Understanding the diversification of phenotypes through time--"descent with modification"--has been the focus of evolutionary biology for 150 years. If, contrary to expectations, similarity evolves in unrelated taxa, researchers are guided to uncover the genetic and developmental mechanisms responsible. Similar phenotypes may be retained from common ancestry (homology), but a phylogenetic context may instead reveal that they are independently derived, due to convergence or parallel evolution, or less likely, that they experienced reversal. Such examples of homoplasy present opportunities to discover the foundations of morphological traits. A common underlying mechanism may exist, and components may have been redeployed in a way that produces the "same" phenotype. New, robust phylogenetic hypotheses and molecular, genomic, and developmental techniques enable integrated exploration of the mechanisms by which similarity arises.

  12. The mind of primitive anthropologists: hemoglobin and HLA, patterns of molecular evolution.

    Science.gov (United States)

    Williams, Robert C

    2003-08-01

    Frank Livingstone played a central role in defining the population genetics of the sickle cell mutation at position 6 of the human beta globin gene, the most famous amino acid substitution in evolutionary biology. Its discovery occurred at a time when traditional, 19th-century principles of natural selection were being joined with the newly discovered mechanics of DNA structure and protein synthesis to produce Neo-Darwinian theory. When combined with the epidemiology of malaria in Africa, differential mortality for both homozygotes, and the resulting advantage of the heterozygote, sickle cell became the classic balanced polymorphism. Human HLA-A has 237 molecular alleles. The histocompatibility system has as its primary function the presentation of peptides to T-cell receptors and plays an essential role in the immune system. Nearly all of the alleles are codominant and fully functional. Despite almost 30 years of disease-association studies with HLA-A, no convincing evidence has been found for differential fertility or mortality at this locus. Yet the dogma in the histocompatibility field is that this extensive human polymorphism is maintained by "balancing selection." Explaining HLA-A polymorphism is what one might call the sickle-cell-effect. This one mutation, coming as it did at the historical convergence of Darwinian theory and modern genetics, and carrying with it the strong relationship between mutation, disease, and allele frequency, has conditioned our discussion of human genetic variation and population genetics. Has the strength of this early idea made evolutionary biologists uncritical of systems like HLA-A and retarded the search for new mechanisms of molecular evolution? Is it now time to move away from a focus on mutation and polymorphism in evolutionary genetics and toward a systems theory that would explain the origin and evolution of hemoglobin and HLA-A and the biochemical pathways that surround them?

  13. Automatic Contour Extraction from 2D Image

    Directory of Open Access Journals (Sweden)

    Panagiotis GIOANNIS

    2011-03-01

    Full Text Available Aim: To develop a method for automatic contour extraction from a 2D image. Material and Method: The method is divided in two basic parts where the user initially chooses the starting point and the threshold. Finally the method is applied to computed tomography of bone images. Results: An interesting method is developed which can lead to a successful boundary extraction of 2D images. Specifically data extracted from a computed tomography images can be used for 2D bone reconstruction. Conclusions: We believe that such an algorithm or part of it can be applied on several other applications for shape feature extraction in medical image analysis and generally at computer graphics.

  14. Optical modulators with 2D layered materials

    Science.gov (United States)

    Sun, Zhipei; Martinez, Amos; Wang, Feng

    2016-04-01

    Light modulation is an essential operation in photonics and optoelectronics. With existing and emerging technologies increasingly demanding compact, efficient, fast and broadband optical modulators, high-performance light modulation solutions are becoming indispensable. The recent realization that 2D layered materials could modulate light with superior performance has prompted intense research and significant advances, paving the way for realistic applications. In this Review, we cover the state of the art of optical modulators based on 2D materials, including graphene, transition metal dichalcogenides and black phosphorus. We discuss recent advances employing hybrid structures, such as 2D heterostructures, plasmonic structures, and silicon and fibre integrated structures. We also take a look at the future perspectives and discuss the potential of yet relatively unexplored mechanisms, such as magneto-optic and acousto-optic modulation.

  15. 2D microwave imaging reflectometer electronics

    Energy Technology Data Exchange (ETDEWEB)

    Spear, A. G.; Domier, C. W., E-mail: cwdomier@ucdavis.edu; Hu, X.; Muscatello, C. M.; Ren, X.; Luhmann, N. C. [Electrical and Computer Engineering, University of California, Davis, California 95616 (United States); Tobias, B. J. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States)

    2014-11-15

    A 2D microwave imaging reflectometer system has been developed to visualize electron density fluctuations on the DIII-D tokamak. Simultaneously illuminated at four probe frequencies, large aperture optics image reflections from four density-dependent cutoff surfaces in the plasma over an extended region of the DIII-D plasma. Localized density fluctuations in the vicinity of the plasma cutoff surfaces modulate the plasma reflections, yielding a 2D image of electron density fluctuations. Details are presented of the receiver down conversion electronics that generate the in-phase (I) and quadrature (Q) reflectometer signals from which 2D density fluctuation data are obtained. Also presented are details on the control system and backplane used to manage the electronics as well as an introduction to the computer based control program.

  16. Assessing 2D electrophoretic mobility spectroscopy (2D MOSY) for analytical applications.

    Science.gov (United States)

    Fang, Yuan; Yushmanov, Pavel V; Furó, István

    2016-12-08

    Electrophoretic displacement of charged entity phase modulates the spectrum acquired in electrophoretic NMR experiments, and this modulation can be presented via 2D FT as 2D mobility spectroscopy (MOSY) spectra. We compare in various mixed solutions the chemical selectivity provided by 2D MOSY spectra with that provided by 2D diffusion-ordered spectroscopy (DOSY) spectra and demonstrate, under the conditions explored, a superior performance of the former method. 2D MOSY compares also favourably with closely related LC-NMR methods. The shape of 2D MOSY spectra in complex mixtures is strongly modulated by the pH of the sample, a feature that has potential for areas such as in drug discovery and metabolomics. Copyright © 2016 The Authors. Magnetic Resonance in Chemistry published by John Wiley & Sons Ltd. StartCopTextCopyright © 2016 The Authors. Magnetic Resonance in Chemistry published by John Wiley & Sons Ltd.

  17. Evolution of Xylan Substitution Patterns in Gymnosperms and Angiosperms: Implications for Xylan Interaction with Cellulose.

    Science.gov (United States)

    Busse-Wicher, Marta; Li, An; Silveira, Rodrigo L; Pereira, Caroline S; Tryfona, Theodora; Gomes, Thiago C F; Skaf, Munir S; Dupree, Paul

    2016-08-01

    The interaction between cellulose and xylan is important for the load-bearing secondary cell wall of flowering plants. Based on the precise, evenly spaced pattern of acetyl and glucuronosyl (MeGlcA) xylan substitutions in eudicots, we recently proposed that an unsubstituted face of xylan in a 2-fold helical screw can hydrogen bond to the hydrophilic surfaces of cellulose microfibrils. In gymnosperm cell walls, any role for xylan is unclear, and glucomannan is thought to be the important cellulose-binding polysaccharide. Here, we analyzed xylan from the secondary cell walls of the four gymnosperm lineages (Conifer, Gingko, Cycad, and Gnetophyta). Conifer, Gingko, and Cycad xylan lacks acetylation but is modified by arabinose and MeGlcA. Interestingly, the arabinosyl substitutions are located two xylosyl residues from MeGlcA, which is itself placed precisely on every sixth xylosyl residue. Notably, the Gnetophyta xylan is more akin to early-branching angiosperms and eudicot xylan, lacking arabinose but possessing acetylation on alternate xylosyl residues. All these precise substitution patterns are compatible with gymnosperm xylan binding to hydrophilic surfaces of cellulose. Molecular dynamics simulations support the stable binding of 2-fold screw conifer xylan to the hydrophilic face of cellulose microfibrils. Moreover, the binding of multiple xylan chains to adjacent planes of the cellulose fibril stabilizes the interaction further. Our results show that the type of xylan substitution varies, but an even pattern of xylan substitution is maintained among vascular plants. This suggests that 2-fold screw xylan binds hydrophilic faces of cellulose in eudicots, early-branching angiosperm, and gymnosperm cell walls.

  18. Optimizing sparse sampling for 2D electronic spectroscopy

    Science.gov (United States)

    Roeding, Sebastian; Klimovich, Nikita; Brixner, Tobias

    2017-02-01

    We present a new data acquisition concept using optimized non-uniform sampling and compressed sensing reconstruction in order to substantially decrease the acquisition times in action-based multidimensional electronic spectroscopy. For this we acquire a regularly sampled reference data set at a fixed population time and use a genetic algorithm to optimize a reduced non-uniform sampling pattern. We then apply the optimal sampling for data acquisition at all other population times. Furthermore, we show how to transform two-dimensional (2D) spectra into a joint 4D time-frequency von Neumann representation. This leads to increased sparsity compared to the Fourier domain and to improved reconstruction. We demonstrate this approach by recovering transient dynamics in the 2D spectrum of a cresyl violet sample using just 25% of the originally sampled data points.

  19. Energetic constraints, not predation, influence the evolution of sleep patterning in mammals

    OpenAIRE

    Capellini, I.; Nunn, C L; McNamara, P; Preston, B T; Barton, R. A.

    2008-01-01

    Mammalian sleep is composed of two distinct states – rapid-eye-movement (REM) and non-REM (NREM) sleep – that alternate in cycles over a sleep bout. The duration of these cycles varies extensively across mammalian species. Because the end of a sleep cycle is often followed by brief arousals to waking, a shorter sleep cycle has been proposed to function as an anti-predator strategy. Similarly, higher predation risk could explain why many species exhibit a polyphasic sleep pattern (division of ...

  20. Three-dimensional effects in directional solidification in hele-shaw cells: nonlinear evolution and pattern selection

    Science.gov (United States)

    Ajaev; Davis

    2000-02-01

    Directional solidification of a dilute binary alloy in a Hele-Shaw cell is modeled by a long-wave nonlinear evolution equation with zero flux and contact-angle conditions at the walls. The basic steady-state solution and its linear stability criteria are found analytically, and the nonlinear system is solved numerically. Concave-down (toward the solid) interfaces under physically realistic conditions are found to be more unstable than the planar front. Weakly nonlinear analysis indicates that subcritical bifurcation is promoted, the domain of modulational instability is expanded and transition to three-dimensional patterns is delayed due to the contact-angle condition. In the strongly nonlinear regime fully three-dimensional steady-state solutions are found whose characteristic amplitude is larger than that for the two-dimensional problem. In the subcritical regime secondary bifurcation to stable solutions is promoted.

  1. 工作团队研究模式的演进%Evolution of Research Patterns of Work Team

    Institute of Scientific and Technical Information of China (English)

    薛继东

    2011-01-01

    从工作团队定义、分类入手,对已有工作团队研究成果进行归纳总结,指出工作团队研究主要经历三种递进模式:IPO、IMO和IMOI,这三种研究模式的演进体现了团队研究复杂、动态、适应和循环的特征,并为未来的团队研究提出建议.%Starting from the definition and types of work teams, the article summarizes three kinds of evolutionary patterns of work team research: IPO, IMO, IMOI. The evolution reflects four characteristics of work team research: complex, dynamic, adaptive and cycling. The article also concludes briefly emerging directions in work team research.

  2. Energetic constraints, not predation, influence the evolution of sleep patterning in mammals.

    Science.gov (United States)

    Capellini, I; Nunn, C L; McNamara, P; Preston, B T; Barton, R A

    2008-10-01

    Mammalian sleep is composed of two distinct states - rapid-eye-movement (REM) and non-REM (NREM) sleep - that alternate in cycles over a sleep bout. The duration of these cycles varies extensively across mammalian species. Because the end of a sleep cycle is often followed by brief arousals to waking, a shorter sleep cycle has been proposed to function as an anti-predator strategy. Similarly, higher predation risk could explain why many species exhibit a polyphasic sleep pattern (division of sleep into several bouts per day), as having multiple sleep bouts avoids long periods of unconsciousness, potentially reducing vulnerability.Using phylogenetic comparative methods, we tested these predictions in mammals, and also investigated the relationships among sleep phasing, sleep-cycle length, sleep durations and body mass.Neither sleep-cycle length nor phasing of sleep was significantly associated with three different measures of predation risk, undermining the idea that they represent anti-predator adaptations.Polyphasic sleep was associated with small body size, shorter sleep cycles and longer sleep durations. The correlation with size may reflect energetic constraints: small animals need to feed more frequently, preventing them from consolidating sleep into a single bout. The reduced daily sleep quotas in monophasic species suggests that the consolidation of sleep into one bout per day may deliver the benefits of sleep more efficiently and, since early mammals were small-bodied and polyphasic, a more efficient monophasic sleep pattern could be a hitherto unrecognized advantage of larger size.

  3. The nocturnal bottleneck and the evolution of activity patterns in mammals.

    Science.gov (United States)

    Gerkema, Menno P; Davies, Wayne I L; Foster, Russell G; Menaker, Michael; Hut, Roelof A

    2013-08-22

    In 1942, Walls described the concept of a 'nocturnal bottleneck' in placental mammals, where these species could survive only by avoiding daytime activity during times in which dinosaurs were the dominant taxon. Walls based this concept of a longer episode of nocturnality in early eutherian mammals by comparing the visual systems of reptiles, birds and all three extant taxa of the mammalian lineage, namely the monotremes, marsupials (now included in the metatherians) and placentals (included in the eutherians). This review describes the status of what has become known as the nocturnal bottleneck hypothesis, giving an overview of the chronobiological patterns of activity. We review the ecological plausibility that the activity patterns of (early) eutherian mammals were restricted to the night, based on arguments relating to endothermia, energy balance, foraging and predation, taking into account recent palaeontological information. We also assess genes, relating to light detection (visual and non-visual systems) and the photolyase DNA protection system that were lost in the eutherian mammalian lineage. Our conclusion presently is that arguments in favour of the nocturnal bottleneck hypothesis in eutherians prevail.

  4. The nocturnal bottleneck and the evolution of activity patterns in mammals

    Science.gov (United States)

    Gerkema, Menno P.; Davies, Wayne I. L.; Foster, Russell G.; Menaker, Michael; Hut, Roelof A.

    2013-01-01

    In 1942, Walls described the concept of a ‘nocturnal bottleneck’ in placental mammals, where these species could survive only by avoiding daytime activity during times in which dinosaurs were the dominant taxon. Walls based this concept of a longer episode of nocturnality in early eutherian mammals by comparing the visual systems of reptiles, birds and all three extant taxa of the mammalian lineage, namely the monotremes, marsupials (now included in the metatherians) and placentals (included in the eutherians). This review describes the status of what has become known as the nocturnal bottleneck hypothesis, giving an overview of the chronobiological patterns of activity. We review the ecological plausibility that the activity patterns of (early) eutherian mammals were restricted to the night, based on arguments relating to endothermia, energy balance, foraging and predation, taking into account recent palaeontological information. We also assess genes, relating to light detection (visual and non-visual systems) and the photolyase DNA protection system that were lost in the eutherian mammalian lineage. Our conclusion presently is that arguments in favour of the nocturnal bottleneck hypothesis in eutherians prevail. PMID:23825205

  5. Osteological evidence for the evolution of activity pattern and visual acuity in primates.

    Science.gov (United States)

    Kay, R F; Kirk, E C

    2000-10-01

    Examination of orbit size and optic foramen size in living primates reveals two adaptive phenomena. First, as noted by many authors, orbit size is strongly correlated with activity pattern. Comparisons of large samples of extant primates consistently reveal that nocturnal species exhibit proportionately larger orbits than diurnal species. Furthermore, nocturnal haplorhines (Tarsius and Aotus) have considerably larger orbits than similar-sized nocturnal strepsirrhines. Orbital hypertrophy in Tarsius and Aotus accommodates the enormously enlarged eyes of these taxa. This extreme ocular hypertrophy seen in extant nocturnal haplorhines is an adaptation for both enhanced visual acuity and sensitivity in conditions of low light intensity. Second, the relative size of the optic foramen is highly correlated with the degree of retinal summation and inferred visual acuity. Diurnal haplorhines exhibit proportionately larger optic foramina, less central retinal summation, and much higher visual acuity than do all other primates. Diurnal strepsirrhines exhibit a more subtle but significant parallel enlargement of the optic foramen and a decrease in retinal summation relative to the condition seen in nocturnal primates. These twin osteological variables of orbit size and optic foramen size may be used to draw inferences regarding the activity pattern, retinal anatomy, and visual acuity of fossil primates. Our measurements demonstrate that the omomyiforms Microchoerus, Necrolemur, Shoshonius, and Tetonius, adapiform Pronycticebus, and the possible lorisiform Plesiopithecus were likely nocturnal on the basis of orbit diameter. The adapiforms Leptadapis, Adapis, and Notharctus, the phylogenetically enigmatic Rooneyia, the early anthropoids Proteopithecus, Catopithecus, and Aegyptopithecus, and early platyrrhine Dolichocebus were likely diurnal. The activity pattern of the platyrrhine Tremacebus is obscure. Plesiopithecus, Pronycticebus, Microchoerus, and Necrolemur probably had

  6. Distinct patterns of HIV-1 evolution within metastatic tissues in patients with non-Hodgkins lymphoma.

    Directory of Open Access Journals (Sweden)

    Marco Salemi

    Full Text Available Despite highly active antiretroviral therapy (HAART, AIDS related lymphoma (ARL occurs at a significantly higher rate in patients infected with the Human Immunodeficiency Virus (HIV than in the general population. HIV-infected macrophages are a known viral reservoir and have been shown to have lymphomagenic potential in SCID mice; therefore, there is an interest in determining if a viral component to lymphomagenesis also exists. We sequenced HIV-1 envelope gp120 clones obtained post mortem from several tumor and non-tumor tissues of two patients who died with AIDS-related Non-Hodgkin's lymphoma (ARL-NH. Similar results were found in both patients: 1 high-resolution phylogenetic analysis showed a significant degree of compartmentalization between lymphoma and non-lymphoma viral sub-populations while viral sub-populations from lymph nodes appeared to be intermixed within sequences from tumor and non-tumor tissues, 2 a 100-fold increase in the effective HIV population size in tumor versus non-tumor tissues was associated with the emergence of lymphadenopathy and aggressive metastatic ARL, and 3 HIV gene flow among lymph nodes, normal and metastatic tissues was non-random. The different population dynamics between the viruses found in tumors versus the non-tumor associated viruses suggest that there is a significant relationship between HIV evolution and lymphoma pathogenesis. Moreover, the study indicates that HIV could be used as an effective marker to study the origin and dissemination of lymphomas in vivo.

  7. Lack of low frequency variants masks patterns of non-neutral evolution following domestication.

    Directory of Open Access Journals (Sweden)

    Céline H Frère

    Full Text Available Detecting artificial selection in the genome of domesticated species can not only shed light on human history but can also be beneficial to future breeding strategies. Evidence for selection has been documented in domesticated species including maize and rice, but few studies have to date detected signals of artificial selection in the Sorghum bicolor genome. Based on evidence that domesticated S. bicolor and its wild relatives show significant differences in endosperm structure and quality, we sequenced three candidate seed storage protein (kafirin loci and three candidate starch biosynthesis loci to test whether these genes show non-neutral evolution resulting from the domestication process. We found strong evidence of non-neutral selection at the starch synthase IIa gene, while both starch branching enzyme I and the beta kafirin gene showed weaker evidence of non-neutral selection. We argue that the power to detect consistent signals of non-neutral selection in our dataset is confounded by the absence of low frequency variants at four of the six candidate genes. A future challenge in the detection of positive selection associated with domestication in sorghum is to develop models that can accommodate for skewed frequency spectrums.

  8. Lack of low frequency variants masks patterns of non-neutral evolution following domestication.

    Science.gov (United States)

    Frère, Céline H; Prentis, Peter J; Gilding, Edward K; Mudge, Agnieszka M; Cruickshank, Alan; Godwin, Ian D

    2011-01-01

    Detecting artificial selection in the genome of domesticated species can not only shed light on human history but can also be beneficial to future breeding strategies. Evidence for selection has been documented in domesticated species including maize and rice, but few studies have to date detected signals of artificial selection in the Sorghum bicolor genome. Based on evidence that domesticated S. bicolor and its wild relatives show significant differences in endosperm structure and quality, we sequenced three candidate seed storage protein (kafirin) loci and three candidate starch biosynthesis loci to test whether these genes show non-neutral evolution resulting from the domestication process. We found strong evidence of non-neutral selection at the starch synthase IIa gene, while both starch branching enzyme I and the beta kafirin gene showed weaker evidence of non-neutral selection. We argue that the power to detect consistent signals of non-neutral selection in our dataset is confounded by the absence of low frequency variants at four of the six candidate genes. A future challenge in the detection of positive selection associated with domestication in sorghum is to develop models that can accommodate for skewed frequency spectrums.

  9. Episode-Based Evolution Pattern Analysis of Haze Pollution: Method Development and Results from Beijing, China.

    Science.gov (United States)

    Zheng, Guangjie; Duan, Fengkui; Ma, Yongliang; Zhang, Qiang; Huang, Tao; Kimoto, Takashi; Cheng, Yafang; Su, Hang; He, Kebin

    2016-05-01

    Haze episodes occurred in Beijing repeatedly in 2013, resulting in 189 polluted days. These episodes differed in terms of sources, formation processes, and chemical composition and thus required different control policies. Therefore, an overview of the similarities and differences among these episodes is needed. For this purpose, we conducted one-year online observations and developed a program that can simultaneously divide haze episodes and identify their shapes. A total of 73 episodes were identified, and their shapes were linked with synoptic conditions. Pure-haze events dominated in wintertime, whereas mixed haze-dust (PM2.5/PM10 haze-fog (Aerosol Water/PM2.5 ∼ 0.3) events dominated in spring and summer-autumn, respectively. For all types, increase of ratio of PM2.5 in PM10 was typically achieved before PM2.5 reached ∼150 μg/m(3). In all PM2.5 species observed, organic matter (OM) was always the most abundant component (18-60%), but it was rarely the driving factor: its relative contribution usually decreased as the pollution level increased. The only OM-driven episode observed was associated with intensive biomass-burning activities. In comparison, haze evolution generally coincided with increasing sulfur and nitrogen oxidation ratios (SOR and NOR), indicating the enhanced production of secondary inorganic species. Applicability of these conclusions required further tests with simultaneously multisite observations.

  10. Evolution of dislocation patterns and its application in prediction of flow stress

    Institute of Scientific and Technical Information of China (English)

    ZHOU Zhimin; SUN Yanrui

    2004-01-01

    The feature of dislocation patterns generated in plastic deformation is the ordered structure of alternative appearance of high and low dislocation density zones. With regard to the system of edge and screw dislocations, a nonlinear partial differential equation (eq. (13) in the text)including high order terms is established based on the reaction-diffusion equation. The contribution of cross slip of screw dislocations to the edge dislocation density is also considered in the analysis. The established equation has the typical feature of nonlinear system. Therefore, one does not need to deal with the complex expressions of the reaction and generation terms for dislocations. By theoretical analysis, the distance between adjacent high dislocation density zones (cell size or distance between cell walls) is obtained. By using this relationship, the flow stresses of ultrafine grained (UFG)copper and aluminum are predicted. The calculated results are well consistent with the experimental.

  11. Angiosperm n-alkane distribution patterns and the geologic record of C4 grassland evolution

    Science.gov (United States)

    Henderson, A.; Graham, H. V.; Patzkowsky, M.; Fox, D. L.; Freeman, K. H.

    2012-12-01

    n-Alkane average chain-length (ACL) patterns vary regionally with community composition and climate. To clarify the influence of phylogenetic and community patterns, we compiled and analyzed a global database of published n-alkane abundance for n-C27 to C35 homologs in modern plant specimens (n=205). ACL for waxes in C4 non-woody plants are longer than for woody plants, suggesting ACL can serve as an indicator of the three-dimensional structure of local vegetation. Further, these findings suggest compound-specific isotopic data for longer alkane homologs (C31, C33, C35) will proportionately represent non-woody vegetation and isotope measurements of C29 are more representative of woody vegetation. Thus, the combination of ACL and carbon isotope compositions should allow us to disentangle C3 woody, C3 non-woody, and C4 non-woody signals in terrestrial paleorecords. Application of this approach to the geologic record of Miocene C4 grassland expansion in the US Great Plains and the Siwaliks in Pakistan illustrate two very different transition scenarios. Alkane-specific isotopic data indicate C4 grasslands appeared 2.5 Ma in the Great Plains and 6.5 Ma in the Siwaliks, and ACL analysis indicates that this transition involved the replacement of woody vegetation in the US and the replacement of C3 grasses in Pakistan. Our analysis illustrates that, consistent with differences in the timing of C4 grassland, the drivers of change were likely not the same in these regions. Oxygen isotope records suggest that the more recent transition in the Great Plains was associated with climate cooling and possibly changes in disturbance regimes and that the transition in the Siwaliks was likely associated with warming and drying.

  12. Horns Rev II, 2-D Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Frigaard, Peter

    This report present the results of 2D physical model tests carried out in the shallow wave flume at Dept. of Civil Engineering, Aalborg University (AAU), on behalf of Energy E2 A/S part of DONG Energy A/S, Denmark. The objective of the tests was: to investigate the combined influence of the pile...

  13. 2D PIM Simulation Based on COMSOL

    DEFF Research Database (Denmark)

    Wang, Xinbo; Cui, Wanzhao; Wang, Jingyu;

    2011-01-01

    Passive intermodulation (PIM) is a problematic type of nonlinear distortion en- countered in many communication systems. To analyze the PIM distortion resulting from ma- terial nonlinearity, a 2D PIM simulation method based on COMSOL is proposed in this paper. As an example, a rectangular wavegui...

  14. Canonical structure of 2D black holes

    CERN Document Server

    Navarro-Salas, J; Talavera, C F

    1994-01-01

    We determine the canonical structure of two-dimensional black-hole solutions arising in $2D$ dilaton gravity. By choosing the Cauchy surface appropriately we find that the canonically conjugate variable to the black hole mass is given by the difference of local (Schwarzschild) time translations at right and left spatial infinities. This can be regarded as a generalization of Birkhoff's theorem.

  15. A new experimental approach for studying bacterial genomic island evolution identifies island genes with bacterial host-specific expression patterns

    Directory of Open Access Journals (Sweden)

    Nickerson Cheryl A

    2006-01-01

    Full Text Available Abstract Background Genomic islands are regions of bacterial genomes that have been acquired by horizontal transfer and often contain blocks of genes that function together for specific processes. Recently, it has become clear that the impact of genomic islands on the evolution of different bacterial species is significant and represents a major force in establishing bacterial genomic variation. However, the study of genomic island evolution has been mostly performed at the sequence level using computer software or hybridization analysis to compare different bacterial genomic sequences. We describe here a novel experimental approach to study the evolution of species-specific bacterial genomic islands that identifies island genes that have evolved in such a way that they are differentially-expressed depending on the bacterial host background into which they are transferred. Results We demonstrate this approach by using a "test" genomic island that we have cloned from the Salmonella typhimurium genome (island 4305 and transferred to a range of Gram negative bacterial hosts of differing evolutionary relationships to S. typhimurium. Systematic analysis of the expression of the island genes in the different hosts compared to proper controls allowed identification of genes with genera-specific expression patterns. The data from the analysis can be arranged in a matrix to give an expression "array" of the island genes in the different bacterial backgrounds. A conserved 19-bp DNA site was found upstream of at least two of the differentially-expressed island genes. To our knowledge, this is the first systematic analysis of horizontally-transferred genomic island gene expression in a broad range of Gram negative hosts. We also present evidence in this study that the IS200 element found in island 4305 in S. typhimurium strain LT2 was inserted after the island had already been acquired by the S. typhimurium lineage and that this element is likely not

  16. Evolution of large body size in abalones (Haliotis): Patterns and implications

    Science.gov (United States)

    Estes, J.A.; Lindberg, D.R.; Wray, C.

    2005-01-01

    Kelps and other fleshy macroalgae - dominant reef-inhabiting organisms in cool - seasmay have radiated extensively following late Cenozoic polar cooling, thus triggering a chain of evolutionary change in the trophic ecology of nearshore temperate ecosystems. We explore this hypothesis through an analysis of body size in the abalones (Gastropoda; Haliotidae), a widely distributed group in modern oceans that displays a broad range of body sizes and contains fossil representatives from the late Cretaceous (60-75 Ma). Geographic analysis of maximum shell length in living abalones showed that small-bodied species, while most common in the Tropics, have a cosmopolitan distribution, whereas large-bodied species occur exclusively in cold-water ecosystems dominated by kelps and other macroalgae. The phylogeography of body size evolution in extant abalones was assessed by constructing a molecular phylogeny in a mix of large and small species obtained from different regions of the world. This analysis demonstrates that small body size is the plesiomorphic state and largeness has likely arisen at least twice. Finally, we compiled data on shell length from the fossil record to determine how (slowly or suddenly) and when large body size arose in the abalones. These data indicate that large body size appears suddenly at the Miocene/Pliocene boundary. Our findings support the view that fleshy-algal dominated ecosystems radiated rapidly in the coastal oceans with the onset of the most recent glacial age. We conclude with a discussion of the broader implications of this change. ?? 2005 The Paleontological Society. All rights reserved.

  17. Design of Spiking Central Pattern Generators for Multiple Locomotion Gaits in Hexapod Robots by Christiansen Grammar Evolution

    Directory of Open Access Journals (Sweden)

    Andrés Espinal

    2016-07-01

    Full Text Available This paper deals with the design of Spiking Central Pattern Generators (SCPGs to achieve locomotion at different frequencies in legged robots and their hardware implementation in a FPGA and validation on a real hexapod robot. Herein, the SCPGs are automatically designed by a Christiansen Grammar Evolution (CGE-based methodology. It is, the CGE performs a solution for the configurations (synaptic weights and connections of each neuron in the SCPG. This is carried out through the indirect representation of a candidate solution that evolves to replicate a specific spike train according to a locomotion pattern (gait by measuring the similarity between the spike train with the SPIKE-Distance to drive the search to a correct configuration. By using this evolutionary approach, several SCPG design specifications can be explicitly added into the fitness function to achieve the SPIKE-distance criteria, such as: looking for SNNs with minimal connectivity or a CPG able to generate different locomotion gaits only by changing the initial input stimuli. The SCPG designs have been successfully implemented on a Spartan 6 FPGA board and a real time validation on a 12 DOFs hexapod robot is presented.

  18. Evolution of OTP-independent larval skeleton patterning in the direct-developing sea urchin, Heliocidaris erythrogramma.

    Science.gov (United States)

    Zhou, Na; Wilson, Keen A; Andrews, Mary E; Kauffman, Jeffery S; Raff, Rudolf A

    2003-12-15

    Heliocidaris erythrogramma is a direct-developing sea urchin that has evolved a modified ontogeny, a reduced larval skeleton, and accelerated development of the adult skeleton. The Orthopedia gene (Otp) encodes a homeodomain transcription factor crucial in patterning the larval skeleton of indirect-developing sea urchins. We compare the role of Otp in larvae of the indirect-developing sea urchin Heliocidaris tuberculata and its direct-developing congener H. erythrogramma. Otp is a single-copy gene with an identical protein sequence in these species. Expression of Otp is initiated by the late gastrula, initially in two cells of the oral ectoderm in H. tuberculata. These cells are restricted to oral ectoderm and exhibit left-right symmetry. There are about 266 copies of Otp mRNA per Otp- expressing cell in H. tuberculata. We tested OTP function in H. tuberculata and H. erythrogramma embryos by microinjection of Otp mRNA. Mis-expression of Otp mRNA in H. tuberculata radialized the embryos and caused defects during larval skeletogenesis. Mis-expression of Otp mRNA in H. erythrogramma embryos did not affect skeleton formation. This is consistent with the observation by in situ hybridization of no concentration of Otp transcript in any particular cells or region of the H. erythrogramma larva, and measurement of a level of less than one copy of endogenous Otp mRNA per cell in H. erythrogramma. OTP plays an important role in patterning the larval skeleton of H. tuberculata, but this role apparently has been lost in the evolution of the H. erythrogramma larva, and replaced by a new patterning mechanism.

  19. Bone microstructure and the evolution of growth patterns in Permo-Triassic therocephalians (Amniota, Therapsida of South Africa

    Directory of Open Access Journals (Sweden)

    Adam K. Huttenlocker

    2014-04-01

    Full Text Available Therocephalians were a speciose clade of nonmammalian therapsids whose ecological diversity and survivorship of the end-Permian mass extinction offer the potential to investigate the evolution of growth patterns across the clade and their underlying influences on post-extinction body size reductions, or ‘Lilliput effects’. We present a phylogenetic survey of limb bone histology and growth patterns in therocephalians from the Middle Permian through Middle Triassic of the Karoo Basin, South Africa. Histologic sections were prepared from 80 limb bones representing 11 genera of therocephalians. Histologic indicators of skeletal growth, including cortical vascularity (%CV and mean primary osteon diameters (POD, were evaluated in a phylogenetic framework and assessed for correlations with other biologically significant variables (e.g., size and robusticity. Changes in %CV and POD correlated strongly with evolutionary changes in body size (i.e., smaller-bodied descendants tended to have lower %CV than their larger-bodied ancestors across the tree. Bone wall thickness tended to be high in early therocephalians and lower in the gracile-limbed baurioids, but showed no general correlation with cross-sectional area or degree of vascularity (and, thus, growth. Clade-level patterns, however, deviated from previously studied within-lineage patterns. For example, Moschorhinus, one of few therapsid genera to have survived the extinction boundary, demonstrated higher %CV in the Triassic than in the Permian despite its smaller size in the extinction aftermath. Results support a synergistic model of size reductions for Triassic therocephalians, influenced both by within-lineage heterochronic shifts in survivor taxa (as reported in Moschorhinus and the dicynodont Lystrosaurus and phylogenetically inferred survival of small-bodied taxa that had evolved short growth durations (e.g., baurioids. These findings mirror the multi-causal Lilliput patterns described in

  20. Bone microstructure and the evolution of growth patterns in Permo-Triassic therocephalians (Amniota, Therapsida) of South Africa.

    Science.gov (United States)

    Huttenlocker, Adam K; Botha-Brink, Jennifer

    2014-01-01

    Therocephalians were a speciose clade of nonmammalian therapsids whose ecological diversity and survivorship of the end-Permian mass extinction offer the potential to investigate the evolution of growth patterns across the clade and their underlying influences on post-extinction body size reductions, or 'Lilliput effects'. We present a phylogenetic survey of limb bone histology and growth patterns in therocephalians from the Middle Permian through Middle Triassic of the Karoo Basin, South Africa. Histologic sections were prepared from 80 limb bones representing 11 genera of therocephalians. Histologic indicators of skeletal growth, including cortical vascularity (%CV) and mean primary osteon diameters (POD), were evaluated in a phylogenetic framework and assessed for correlations with other biologically significant variables (e.g., size and robusticity). Changes in %CV and POD correlated strongly with evolutionary changes in body size (i.e., smaller-bodied descendants tended to have lower %CV than their larger-bodied ancestors across the tree). Bone wall thickness tended to be high in early therocephalians and lower in the gracile-limbed baurioids, but showed no general correlation with cross-sectional area or degree of vascularity (and, thus, growth). Clade-level patterns, however, deviated from previously studied within-lineage patterns. For example, Moschorhinus, one of few therapsid genera to have survived the extinction boundary, demonstrated higher %CV in the Triassic than in the Permian despite its smaller size in the extinction aftermath. Results support a synergistic model of size reductions for Triassic therocephalians, influenced both by within-lineage heterochronic shifts in survivor taxa (as reported in Moschorhinus and the dicynodont Lystrosaurus) and phylogenetically inferred survival of small-bodied taxa that had evolved short growth durations (e.g., baurioids). These findings mirror the multi-causal Lilliput patterns described in marine faunas, but

  1. Morphotectonic analysis, structural evolution/pattern of a contractional ridge: Giouchtas Mt., Central Crete, Greece

    Indian Academy of Sciences (India)

    Kokinou Eleni; Skilodimou Hariklia D; Bathrellos George D; Antonarakou Assimina; Kamberis Evangelos

    2015-04-01

    The Giouchtas Mountain is situated south of Heraklion, Central Crete. It is a N–S trending morphological asymmetric ridge with a steep western slope, whilst its eastern slope is characterized by a smoother relief, composed of Mesozoic limestone and Eocene–lower Oligocene flysch of the Gavrovo–Tripolis zone. The present study focusses on the structural pattern and development of Giouchtas Mountain. Morphotectonic analyses in combination with field mapping and tectonic analysis were performed for this purpose. GIS techniques were used for mapping the spatial distribution of the geological features on the topographic relief of the area. Geomorphic indices, used in the present study, are the mountain front sinuosity index (Smf) and the valley floor/width ratio index (Vf). Based on Smf and Vf values, it is implied that this area can be assigned to a tectonic class I, corresponding to higher tectonic activity. However, spatial variations of the tectonic activity along the segmented fronts point to a general trend of increasing activity towards the north and especially, northeast. The model of this possibly active structural feature corresponds to a compressional mechanism followed by an earliest Mid. Miocene to Holocene late-stage deformation related to extensional faulting.

  2. Long bone histology and growth patterns in ankylosaurs: implications for life history and evolution.

    Science.gov (United States)

    Stein, Martina; Hayashi, Shoji; Sander, P Martin

    2013-01-01

    The ankylosaurs are one of the major dinosaur groups and are characterized by unique body armor. Previous studies on other dinosaur taxa have revealed growth patterns, life history and evolutionary mechanisms based on their long bone histology. However, to date nothing is known about long bone histology in the Ankylosauria. This study is the first description of ankylosaurian long bone histology based on several limb elements, which were sampled from different individuals from the Ankylosauridae and Nodosauridae. The histology is compared to that of other dinosaur groups, including other Thyreophora and Sauropodomorpha. Ankylosaur long bone histology is characterized by a fibrolamellar bone architecture. The bone matrix type in ankylosaurs is closest to that of Stegosaurus. A distinctive mixture of woven and parallel-fibered bone together with overall poor vascularization indicates slow growth rates compared to other dinosaurian taxa. Another peculiar characteristic of ankylosaur bone histology is the extensive remodeling in derived North American taxa. In contrast to other taxa, ankylosaurs substitute large amounts of their primary tissue early in ontogeny. This anomaly may be linked to the late ossification of the ankylosaurian body armor. Metabolically driven remodeling processes must have liberated calcium to ossify the protective osteodermal structures in juveniles to subadult stages, which led to further remodeling due to increased mechanical loading. Abundant structural fibers observed in the primary bone and even in remodeled bone may have improved the mechanical properties of the Haversian bone.

  3. Fluctuation-induced patterns and rapid evolution in predator-prey ecosystems

    Science.gov (United States)

    Goldenfeld, Nigel

    2014-03-01

    Predator-prey ecosystems exhibit noisy, persistent cycles that cannot be described by intuitive population-level differential equations such as the Lotka-Volterra equations. Traditionally this paradox has been met by including additional nonlinearities such as predator satiation to force limit cycle behavior. Over the last few years, it has been realized that individual-level descriptions, combined with systematic perturbation techniques can reproduce the key features of such systems in a minimal way, without requiring many additional assumptions or fine tunings. Here I review work in this area that uses these techniques to treat spatial patterns and the phenomenon of rapidly evolving prey sub-populations. In the latter case, I show how stochastic individual-level models reproduce the key features observed in chemostats and in the wild, including anomalous phase shifts between predator and prey species, evolutionary cycles and cryptic cycles. This work shows that stochastic individual-level models naturally describe systems where evolutionary time scales surprisingly match ecosystem time scales.

  4. Long bone histology and growth patterns in ankylosaurs: implications for life history and evolution.

    Directory of Open Access Journals (Sweden)

    Martina Stein

    Full Text Available The ankylosaurs are one of the major dinosaur groups and are characterized by unique body armor. Previous studies on other dinosaur taxa have revealed growth patterns, life history and evolutionary mechanisms based on their long bone histology. However, to date nothing is known about long bone histology in the Ankylosauria. This study is the first description of ankylosaurian long bone histology based on several limb elements, which were sampled from different individuals from the Ankylosauridae and Nodosauridae. The histology is compared to that of other dinosaur groups, including other Thyreophora and Sauropodomorpha. Ankylosaur long bone histology is characterized by a fibrolamellar bone architecture. The bone matrix type in ankylosaurs is closest to that of Stegosaurus. A distinctive mixture of woven and parallel-fibered bone together with overall poor vascularization indicates slow growth rates compared to other dinosaurian taxa. Another peculiar characteristic of ankylosaur bone histology is the extensive remodeling in derived North American taxa. In contrast to other taxa, ankylosaurs substitute large amounts of their primary tissue early in ontogeny. This anomaly may be linked to the late ossification of the ankylosaurian body armor. Metabolically driven remodeling processes must have liberated calcium to ossify the protective osteodermal structures in juveniles to subadult stages, which led to further remodeling due to increased mechanical loading. Abundant structural fibers observed in the primary bone and even in remodeled bone may have improved the mechanical properties of the Haversian bone.

  5. Application of 2D Non-Graphene Materials and 2D Oxide Nanostructures for Biosensing Technology.

    Science.gov (United States)

    Shavanova, Kateryna; Bakakina, Yulia; Burkova, Inna; Shtepliuk, Ivan; Viter, Roman; Ubelis, Arnolds; Beni, Valerio; Starodub, Nickolaj; Yakimova, Rositsa; Khranovskyy, Volodymyr

    2016-02-06

    The discovery of graphene and its unique properties has inspired researchers to try to invent other two-dimensional (2D) materials. After considerable research effort, a distinct "beyond graphene" domain has been established, comprising the library of non-graphene 2D materials. It is significant that some 2D non-graphene materials possess solid advantages over their predecessor, such as having a direct band gap, and therefore are highly promising for a number of applications. These applications are not limited to nano- and opto-electronics, but have a strong potential in biosensing technologies, as one example. However, since most of the 2D non-graphene materials have been newly discovered, most of the research efforts are concentrated on material synthesis and the investigation of the properties of the material. Applications of 2D non-graphene materials are still at the embryonic stage, and the integration of 2D non-graphene materials into devices is scarcely reported. However, in recent years, numerous reports have blossomed about 2D material-based biosensors, evidencing the growing potential of 2D non-graphene materials for biosensing applications. This review highlights the recent progress in research on the potential of using 2D non-graphene materials and similar oxide nanostructures for different types of biosensors (optical and electrochemical). A wide range of biological targets, such as glucose, dopamine, cortisol, DNA, IgG, bisphenol, ascorbic acid, cytochrome and estradiol, has been reported to be successfully detected by biosensors with transducers made of 2D non-graphene materials.

  6. Evolution of the binge drinking pattern in college students: neurophysiological correlates.

    Science.gov (United States)

    López-Caneda, Eduardo; Rodríguez Holguín, Socorro; Corral, Montserrat; Doallo, Sonia; Cadaveira, Fernando

    2014-08-01

    It is well known that alcohol impairs response inhibition and that adolescence is a critical period of neuromaturation where cognitive processes such as inhibitory control are still developing. In recent years, growing evidence has shown the negative consequences of alcohol binge drinking on the adolescent and young human brain. However, the effects of cessation of binge drinking on brain function remain unexplored. The objective of the present study was to examine brain activity during response execution and inhibition in young binge drinkers in relation to the progression of their drinking habits over time. Event-related potentials (ERPs) elicited by a Go/NoGo task were recorded twice within a 2-year interval in 57 undergraduate students (25 controls, 22 binge drinkers, and 10 ex-binge drinkers) with no personal or family history of alcoholism or psychopathological disorders. The results showed that the amplitude of NoGo-P3 over the frontal region correlated with an earlier age of onset of regular drinking as well as with greater quantity and speed of alcohol consumption. Regression analysis showed that NoGo-P3 amplitude was significantly predicted by the speed of alcohol intake and the age of onset of regular drinking. The group comparisons showed that, after maintaining a binge drinking pattern for at least 2 years, binge drinkers displayed significantly larger NoGo-P3 amplitudes than controls, whereas ex-binge drinkers were in an intermediate position between the two other groups (with no significant differences with respect to controls or binge drinkers). These findings suggest that binge drinking in young people may impair the neural functioning related to inhibitory processes, and that the cessation of binge drinking may act as a brake on the neurophysiological impairments related to response inhibition.

  7. Design Application Translates 2-D Graphics to 3-D Surfaces

    Science.gov (United States)

    2007-01-01

    Fabric Images Inc., specializing in the printing and manufacturing of fabric tension architecture for the retail, museum, and exhibit/tradeshow communities, designed software to translate 2-D graphics for 3-D surfaces prior to print production. Fabric Images' fabric-flattening design process models a 3-D surface based on computer-aided design (CAD) specifications. The surface geometry of the model is used to form a 2-D template, similar to a flattening process developed by NASA's Glenn Research Center. This template or pattern is then applied in the development of a 2-D graphic layout. Benefits of this process include 11.5 percent time savings per project, less material wasted, and the ability to improve upon graphic techniques and offer new design services. Partners include Exhibitgroup/Giltspur (end-user client: TAC Air, a division of Truman Arnold Companies Inc.), Jack Morton Worldwide (end-user client: Nickelodeon), as well as 3D Exhibits Inc., and MG Design Associates Corp.

  8. Schottky diodes from 2D germanane

    Science.gov (United States)

    Sahoo, Nanda Gopal; Esteves, Richard J.; Punetha, Vinay Deep; Pestov, Dmitry; Arachchige, Indika U.; McLeskey, James T.

    2016-07-01

    We report on the fabrication and characterization of a Schottky diode made using 2D germanane (hydrogenated germanene). When compared to germanium, the 2D structure has higher electron mobility, an optimal band-gap, and exceptional stability making germanane an outstanding candidate for a variety of opto-electronic devices. One-atom-thick sheets of hydrogenated puckered germanium atoms have been synthesized from a CaGe2 framework via intercalation and characterized by XRD, Raman, and FTIR techniques. The material was then used to fabricate Schottky diodes by suspending the germanane in benzonitrile and drop-casting it onto interdigitated metal electrodes. The devices demonstrate significant rectifying behavior and the outstanding potential of this material.

  9. 2D-Tasks for Cognitive Rehabilitation

    OpenAIRE

    Caballero Hernandez, Ruth; Martinez Moreno, Jose Maria; García Molina, A.; Ferrer Celma, S.; Solana Sánchez, Javier; Sanchez Carrion, R.; Fernandez Casado, E.; Pérez Rodríguez, Rodrigo; Gomez Pulido, A.; Anglès Tafalla, C.; Cáceres Taladriz, César; Ferre Vergada, M.; Roig Rovira, Teresa; Garcia Lopez, P.; Tormos Muñoz, Josep M.

    2011-01-01

    Neuropsychological Rehabilitation is a complex clinic process which tries to restore or compensate cognitive and behavioral disorders in people suffering from a central nervous system injury. Information and Communication Technologies (ICTs) in Biomedical Engineering play an essential role in this field, allowing improvement and expansion of present rehabilitation programs. This paper presents a set of cognitive rehabilitation 2D-Tasks for patients with Acquired Brain Injury (ABI). These t...

  10. 2D Metals by Repeated Size Reduction.

    Science.gov (United States)

    Liu, Hanwen; Tang, Hao; Fang, Minghao; Si, Wenjie; Zhang, Qinghua; Huang, Zhaohui; Gu, Lin; Pan, Wei; Yao, Jie; Nan, Cewen; Wu, Hui

    2016-10-01

    A general and convenient strategy for manufacturing freestanding metal nanolayers is developed on large scale. By the simple process of repeatedly folding and calendering stacked metal sheets followed by chemical etching, free-standing 2D metal (e.g., Ag, Au, Fe, Cu, and Ni) nanosheets are obtained with thicknesses as small as 1 nm and with sizes of the order of several micrometers.

  11. Engineering light outcoupling in 2D materials

    KAUST Repository

    Lien, Derhsien

    2015-02-11

    When light is incident on 2D transition metal dichalcogenides (TMDCs), it engages in multiple reflections within underlying substrates, producing interferences that lead to enhancement or attenuation of the incoming and outgoing strength of light. Here, we report a simple method to engineer the light outcoupling in semiconducting TMDCs by modulating their dielectric surroundings. We show that by modulating the thicknesses of underlying substrates and capping layers, the interference caused by substrate can significantly enhance the light absorption and emission of WSe2, resulting in a ∼11 times increase in Raman signal and a ∼30 times increase in the photoluminescence (PL) intensity of WSe2. On the basis of the interference model, we also propose a strategy to control the photonic and optoelectronic properties of thin-layer WSe2. This work demonstrates the utilization of outcoupling engineering in 2D materials and offers a new route toward the realization of novel optoelectronic devices, such as 2D LEDs and solar cells.

  12. Irreversibility-inversions in 2D turbulence

    Science.gov (United States)

    Bragg, Andrew; de Lillo, Filippo; Boffetta, Guido

    2016-11-01

    We consider a recent theoretical prediction that for inertial particles in 2D turbulence, the nature of the irreversibility of their pair dispersion inverts when the particle inertia exceeds a certain value. In particular, when the particle Stokes number, St , is below a certain value, the forward-in-time (FIT) dispersion should be faster than the backward-in-time (BIT) dispersion, but for St above this value, this should invert so that BIT becomes faster than FIT dispersion. This non-trivial behavior arises because of the competition between two physically distinct irreversibility mechanisms that operate in different regimes of St . In 3D turbulence, both mechanisms act to produce faster BIT than FIT dispersion, but in 2D, the two mechanisms have opposite effects because of the inverse energy cascade in the turbulent velocity field. We supplement the qualitative argument given by Bragg et al. by deriving quantitative predictions of this effect in the short-time dispersion limit. These predictions are then confirmed by results of inertial particle dispersion in a direct numerical simulation of 2D turbulence.

  13. Evolution of geographical place and niche space: Patterns of diversification in the North American sedge (Cyperaceae) flora.

    Science.gov (United States)

    Spalink, Daniel; Drew, Bryan T; Pace, Matthew C; Zaborsky, John G; Li, Pan; Cameron, Kenneth M; Givnish, Thomas J; Sytsma, Kenneth J

    2016-02-01

    The role of geography and ecology in speciation are often discussed in the context of phylogenetic niche conservatism (PNC), the propensity of lineages to retain ancestral niche related traits. However, a recent paradigm shift focuses instead on measuring divergence of these traits in conjunction with patterns of speciation. Under this framework, we analyzed the diversification of North America's third most diverse family, Cyperaceae ("sedges"), using a modified Parsimony Analysis of Endemicity approach to identify floristic regions and ordination statistics to quantify species distribution in a continuous manner. Utilizing over 200,000 georeferenced specimens, we characterized the geographical distribution and climatic and edaphic niche space occupied by each species. We constructed a supermatrix phylogeny of the North American sedge flora, aided in part by the sequencing of all sedges of Wisconsin, and employed a multifaceted approach to assess the role of geographical and ecological divergence on lineage diversification. In addition to measuring phylogenetic signal for these traits, we also measured pairwise phylogenetic distance of species within floristic regions, calculated rates of speciation, and tested for correlations of speciation rate to tempo of geographical and ecological evolution. Our analyses consistently show that evolutionarily related species tend to be geographically unrelated. Rates of geographical and ecological diversification are closely linked to tempo of speciation, and exploration of geographical place coincides with divergence in ecological niche space. We highlight the benefits of treating geography in a continuous manner, and stress the importance of employing a diverse suite of analytical approaches in testing hypotheses regarding the evolution of range and niche.

  14. Patterns in root traits of woody species hosting arbuscular and ectomycorrhizas: implications for the evolution of belowground strategies.

    Science.gov (United States)

    Comas, Louise H; Callahan, Hilary S; Midford, Peter E

    2014-08-01

    Root traits vary enormously among plant species but we have little understanding of how this variation affects their functioning. Of central interest is how root traits are related to plant resource acquisition strategies from soil. We examined root traits of 33 woody species from northeastern US forests that form two of the most common types of mutualisms with fungi, arbuscular mycorrhizas (AM) and ectomycorrhizas (EM). We examined root trait distribution with respect to plant phylogeny, quantifying the phylogenetic signal (K statistic) in fine root morphology and architecture, and used phylogenetically independent contrasts (PICs) to test whether taxa forming different mycorrhizal associations had different root traits. We found a pattern of species forming roots with thinner diameters as species diversified across time. Given moderate phylogenetic signals (K = 0.44-0.68), we used PICs to examine traits variation among taxa forming AM or EM, revealing that hosts of AM were associated with lower branching intensity (r PIC = -0.77) and thicker root diameter (r PIC = -0.41). Because EM evolved relatively more recently and intermittently across plant phylogenies, significant differences in root traits and colonization between plants forming AM and EM imply linkages between the evolution of these biotic interactions and root traits and suggest a history of selection pressures, with trade-offs for supporting different types of associations. Finally, across plant hosts of both EM and AM, species with thinner root diameters and longer specific root length (SRL) had less colonization (r PIC = 0.85, -0.87), suggesting constraints on colonization linked to the evolution of root morphology.

  15. Trends and patterns of anthropogenic evolution of chernozems in lands of agricultural afforestation within the territory of forest-steppe in the center of eastern Europe

    Science.gov (United States)

    The anthropogenic evolution of chernozems as a result of plowing and the creation of forest shelterbelts on three meadow-steppe areas of forest-steppe were studied. It was established, that in all areas there are similar patterns, caused by the transformation of virgin soils into arable soils and vi...

  16. 2D superconductivity by ionic gating

    Science.gov (United States)

    Iwasa, Yoshi

    2D superconductivity is attracting a renewed interest due to the discoveries of new highly crystalline 2D superconductors in the past decade. Superconductivity at the oxide interfaces triggered by LaAlO3/SrTiO3 has become one of the promising routes for creation of new 2D superconductors. Also, the MBE grown metallic monolayers including FeSe are also offering a new platform of 2D superconductors. In the last two years, there appear a variety of monolayer/bilayer superconductors fabricated by CVD or mechanical exfoliation. Among these, electric field induced superconductivity by electric double layer transistor (EDLT) is a unique platform of 2D superconductivity, because of its ability of high density charge accumulation, and also because of the versatility in terms of materials, stemming from oxides to organics and layered chalcogenides. In this presentation, the following issues of electric filed induced superconductivity will be addressed; (1) Tunable carrier density, (2) Weak pinning, (3) Absence of inversion symmetry. (1) Since the sheet carrier density is quasi-continuously tunable from 0 to the order of 1014 cm-2, one is able to establish an electronic phase diagram of superconductivity, which will be compared with that of bulk superconductors. (2) The thickness of superconductivity can be estimated as 2 - 10 nm, dependent on materials, and is much smaller than the in-plane coherence length. Such a thin but low resistance at normal state results in extremely weak pinning beyond the dirty Boson model in the amorphous metallic films. (3) Due to the electric filed, the inversion symmetry is inherently broken in EDLT. This feature appears in the enhancement of Pauli limit of the upper critical field for the in-plane magnetic fields. In transition metal dichalcogenide with a substantial spin-orbit interactions, we were able to confirm the stabilization of Cooper pair due to its spin-valley locking. This work has been supported by Grant-in-Aid for Specially

  17. The Influence of Facial Characteristics on the Relation between Male 2D:4D and Dominance.

    Directory of Open Access Journals (Sweden)

    Jan Ryckmans

    Full Text Available Although relations between 2D:4D and dominance rank in both baboons and rhesus macaques have been observed, evidence in humans is mixed. Whereas behavioral patterns in humans have been discovered that are consistent with these animal findings, the evidence for a relation between dominance and 2D:4D is weak or inconsistent. The present study provides experimental evidence that male 2D:4D is related to dominance after (fictitious male-male interaction when the other man has a dominant, but not a submissive or neutral face. This finding provides evidence that the relationship between 2D:4D and dominance emerges in particular, predictable situations and that merely dominant facial characteristics of another person are enough to activate supposed relationships between 2D:4D and dominance.

  18. Sequence, evolution and tissue expression patterns of an epidermal type I keratin from the shark Scyliorhinus stellaris.

    Science.gov (United States)

    Schaffeld, Michael; Höffling, Simon; Jürgen, Markl

    2004-08-01

    From the shark Scyliorhinus stellaris we cloned and sequenced a cDNA encoding a novel type I keratin, termed SstK10. By MALDI-MS peptide mass fingerprinting of cytoskeletal proteins separated on polyacrylamide gels, we assigned SstK10 to a 46-kDa protein which is the major epidermal type I ("IE") keratin in this fish and is specifically expressed in stratified epithelia. In a phylogenetic tree based on type I keratin sequences and with lamprey keratins applied as outgroup, SstK10 branches off in a rather basal position. This tree strongly supports the concept that teleost keratins and tetrapod keratins resulted from two independent gene radiation processes. The only exception is human K18 because its orthologs have been found in all jawed vertebrates (Gnathostomata) studied; in the tree, they form a common, most early branch, with the shark version, SstK18, in the most basal position. Thus, the sequences of SstK10 and SstK18 also favor the classical view of vertebrate evolution that considers the cartilaginous fishes as the most ancient living Gnathostomata. To determine the overall expression patterns of epidermal ("E") and simple epithelial ("S") keratins in this shark, we furthermore tested a panel of monoclonal anti-keratin antibodies by immunofluorescence microscopy of frozen tissue sections, and in immunoblots of cytoskeletal preparations, demonstrating that immunodetection of specific keratins is a convenient method to characterize epithelial tissues in shark.

  19. GBL-2D Version 1.0: a 2D geometry boolean library.

    Energy Technology Data Exchange (ETDEWEB)

    McBride, Cory L. (Elemental Technologies, American Fort, UT); Schmidt, Rodney Cannon; Yarberry, Victor R.; Meyers, Ray J. (Elemental Technologies, American Fort, UT)

    2006-11-01

    This report describes version 1.0 of GBL-2D, a geometric Boolean library for 2D objects. The library is written in C++ and consists of a set of classes and routines. The classes primarily represent geometric data and relationships. Classes are provided for 2D points, lines, arcs, edge uses, loops, surfaces and mask sets. The routines contain algorithms for geometric Boolean operations and utility functions. Routines are provided that incorporate the Boolean operations: Union(OR), XOR, Intersection and Difference. A variety of additional analytical geometry routines and routines for importing and exporting the data in various file formats are also provided. The GBL-2D library was originally developed as a geometric modeling engine for use with a separate software tool, called SummitView [1], that manipulates the 2D mask sets created by designers of Micro-Electro-Mechanical Systems (MEMS). However, many other practical applications for this type of software can be envisioned because the need to perform 2D Boolean operations can arise in many contexts.

  20. Mining of the Topic Evolution Pattern of Network News%网络新闻话题演化模式挖掘

    Institute of Scientific and Technical Information of China (English)

    赵旭剑; 张立; 李波; 张晖; 杨春明; 喻琼; 王耀彬

    2015-01-01

    针对特定主题的新闻话题演化模式挖掘对于话题动态演化研究具有重要的研究意义和应用价值,能帮助人们清晰地梳理话题事件的来龙去脉,直观地展现话题演化轨迹的逻辑结构。针对该需求,本文提出一种面向特定话题的网络新闻话题演化模式挖掘方法,拟从挖掘话题演化逻辑的角度出发,针对特定话题(矿难事件)进行话题演化一般规律的深入分析,对话题演变过程进行阶段化表示,建立话题演化模式。实验结果表明,本文构建的特定话题演化模式具有较强的语义表达能力,符合话题逻辑。%Patterns mining for topic evolution of topic-specific news is of great significance and value in the research on topic dynamic evolution. It can help people clearly sort out topics of the whole story and intuitively show the logical structure of the topic evolution track. According to the requirement, this paper proposes a pattern mining method for topic-specific news evolution. Firstly, this method takes the in-depth analysis to the general rules of the topic evolution for the specific topic from the logical point of view of the topic evolution discovery, and then studies the topic evolution stage representation to establish the topic evolution patterns. Experimental results show that the topic-specific evolution pattern constructed in this paper has strong semantic expression ability, and accords with the topic logic.

  1. Another solution of 2D Ising model

    Science.gov (United States)

    Vergeles, S. N.

    2009-04-01

    The partition function of the Ising model on a two-dimensional regular lattice is calculated by using the matrix representation of a Clifford algebra (the Dirac algebra), with number of generators equal to the number of lattice sites. It is shown that the partition function over all loops in a 2D lattice including self-intersecting ones is the trace of a polynomial in terms of Dirac matrices. The polynomial is an element of the rotation group in the spinor representation. Thus, the partition function is a function of a character on an orthogonal group of a high degree in the spinor representation.

  2. Instant HTMl5 2D platformer

    CERN Document Server

    Temple, Aidan

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. The step-by-step approach taken by this book will show you how to develop a 2D HTML5 platformer-based game that you will be able to publish to multiple devices.This book is great for anyone who has an interest in HTML5 games development, and who already has a basic to intermediate grasp on both the HTML markup and JavaScript programming languages. Therefore, due to this requirement, the book will not discuss the inner workings of either of these languages but will instead attempt to

  3. Robust and resistant 2D shape alignment

    DEFF Research Database (Denmark)

    Larsen, Rasmus; Eiriksson, Hrafnkell

    2001-01-01

    \\_\\$\\backslash\\$infty\\$ norm alignments are formulated as linear programming problems. The linear vector function formulation along with the different norms results in alignment methods that are both resistant from influence from outliers, robust wrt. errors in the annotation and capable of handling missing datapoints......We express the alignment of 2D shapes as the minimization of the norm of a linear vector function. The minimization is done in the \\$l\\_1\\$, \\$l\\_2\\$ and the \\$l\\_\\$\\backslash\\$infty\\$ norms using well known standard numerical methods. In particular, the \\$l\\_1\\$ and the \\$l...

  4. Extrinsic curvature induced 2-d gravity

    CERN Document Server

    Viswanathan, K S

    1993-01-01

    Abtract: 2-dimensional fermions are coupled to extrinsic geometry of a conformally immersed surface in ${\\bf R}^3$ through gauge coupling. By integrating out the fermions, we obtain a WZNW action involving extrinsic curvature of the surface. Restricting the resulting effective action to surfaces of $h\\sqrt g=1$, an explicit form of the action invariant under Virasaro symmetry is obtained. This action is a sum of the geometric action for the Virasaro group and the light-cone action of 2-d gravity plus an interaction term. The central charges of the theory in both the left and right sectors are calculated.

  5. 2D vibrational properties of epitaxial silicene on Ag(111)

    Science.gov (United States)

    Solonenko, Dmytro; Gordan, Ovidiu D.; Le Lay, Guy; Sahin, Hasan; Cahangirov, Seymur; Zahn, Dietrich R. T.; Vogt, Patrick

    2017-03-01

    The two-dimensional silicon allotrope, silicene, could spur the development of new and original concepts in Si-based nanotechnology. Up to now silicene can only be epitaxially synthesized on a supporting substrate such as Ag(111). Even though the structural and electronic properties of these epitaxial silicene layers have been intensively studied, very little is known about its vibrational characteristics. Here, we present a detailed study of epitaxial silicene on Ag(111) using in situ Raman spectroscopy, which is one of the most extensively employed experimental techniques to characterize 2D materials, such as graphene, transition metal dichalcogenides, and black phosphorous. The vibrational fingerprint of epitaxial silicene, in contrast to all previous interpretations, is characterized by three distinct phonon modes with A and E symmetries. Both, energies and symmetries of theses modes are confirmed by ab initio theory calculations. The temperature dependent spectral evolution of these modes demonstrates unique thermal properties of epitaxial silicene and a significant electron-phonon coupling. These results unambiguously support the purely two-dimensional character of epitaxial silicene up to about 300 °C, whereupon a 2D-to-3D phase transition takes place. The detailed fingerprint of epitaxial silicene will allow us to identify it in different environments or to study its modifications.

  6. Optimal Control of 1D and 2D Circuit QED

    CERN Document Server

    Fisher, R; Glaser, S J; Marquardt, F; Schulte-Herbrueggen, T

    2009-01-01

    Optimal control can be used to significantly improve multi-qubit gates in quantum information processing hardware architectures based on superconducting circuit quantum electrodynamics. We apply this approach not only to dispersive gates of two qubits inside a cavity, but, more generally, to architectures based on two-dimensional arrays of cavities and qubits. For high-fidelity gate operations, simultaneous evolutions of controls and couplings in the two coupling dimensions of cavity grids are shown to be significantly faster than conventional sequential implementations. Even under experimentally realistic conditions speedups by a factor of three can be gained. The methods immediately scale to large grids and indirect gates between arbitrary pairs of qubits on the grid. They are anticipated to be paradigmatic for 2D arrays and lattices of controllable qubits.

  7. Human NKG2D-ligands: cell biology strategies to ensure immune recognition

    Directory of Open Access Journals (Sweden)

    Lola eFernández-Messina

    2012-09-01

    Full Text Available Immune recognition mediated by the activating receptor NKG2D plays an important role for the elimination of stressed cells, including tumours and virus-infected cells. On the other hand, the ligands for NKG2D can also be shed into the sera of cancer patients where they weaken the immune response by downmodulating the receptor on effector cells, mainly NK and T cells. Although both families of NKG2D-ligands, MICA/B and ULBPs, are related to MHC molecules and their expression is increased after stress, many differences are observed in terms of their biochemical properties and cell trafficking. In this paper, we summarise the variety of NKG2D-ligands and propose that selection pressure has driven evolution of diversity in their trafficking and shedding, but not receptor binding affinity. However, it is also possible to identify functional properties common to individual ULBP molecules and MICA/B alleles, but not generally conserved within the MIC or ULBP families. These characteristics likely represent examples of convergent evolution for efficient immune recognition, but are also attractive targets for pathogen immune evasion strategies. Categorization of NKG2D-ligands according to their biological features, rather than their genetic family, may help to achieve a better understanding of NKG2D-ligand association with disease.

  8. Buckling in quasi-2D polymers

    NARCIS (Netherlands)

    Edmondson, S; Frieda, K; Comrie, JE; Onck, PR; Huck, WTS

    2006-01-01

    Buckle-driven delamination and subsequent collapse of strained thin polymer films upon triggered release from the substrate is exploited to fabricate striking, well-defined ridging patterns (see figure). An analysis of these patterns is presented, including the effects of film thickness and the exte

  9. A Comprehensive Analysis of Fermi Gamma-ray Burst Data: II. $E_{\\rm p}$-Evolution Patterns and Implications for the Observed Spectrum-Luminosity Relations

    CERN Document Server

    Lu, Rui-Jing; Liang, En-Wei; Zhang, Bin-Bin; Lü, Hou-Jun; Lian-Zhong,; Lü,; Lei, Wei-Hua; Zhang, Bing

    2012-01-01

    We present a time-resolved spectral analysis of 51 long and 11 short bright GRBs observed with the {\\em Femri}/GBM, paying special attention to $E_{\\rm p}$ evolution within a same burst. Among 8 single-pulse long GRBs, 5 show hard-to-soft evolution, while 3 show intensity-tracking. The multi-pulse long GRBs have more complicated patterns. Among the GRBs whose time-resolved spectrum is available for the first pulse, almost half (15/32 GRBs) show clear hard-to-soft evolution, and the other half (17/32 GRBs) show clear intensity-tracking. Later pulses typically show the tracking behavior, although a hard-to-soft evolution pattern was identified in the 2nd pulse of 2 GRBs whose pulses are well separated. Statistically, the hard-to-soft evolution pulses tend to be more asymmetric than the intensity-tracking ones, with a steeper rising wing than the falling wing. Short GRBs have $E_{\\rm p}$ tracking intensity exclusively with the 16ms time resolution analysis. We performed a simulation analysis, and suggest that at...

  10. Comments on Thermalization in 2D CFT

    CERN Document Server

    de Boer, Jan

    2016-01-01

    We revisit certain aspects of thermalization in 2D CFT. In particular, we consider similarities and differences between the time dependence of correlation functions in various states in rational and non-rational CFTs. We also consider the distinction between global and local thermalization and explain how states obtained by acting with a diffeomorphism on the ground state can appear locally thermal, and we review why the time-dependent expectation value of the energy-momentum tensor is generally a poor diagnostic of global thermalization. Since all 2D CFTs have an infinite set of commuting conserved charges, generic initial states might be expected to give rise to a generalized Gibbs ensemble rather than a pure thermal ensemble at late times. We construct the holographic dual of the generalized Gibbs ensemble and show that, to leading order, it is still described by a BTZ black hole. The extra conserved charges, while rendering $c < 1$ theories essentially integrable, therefore seem to have little effect o...

  11. Remarks on thermalization in 2D CFT

    Science.gov (United States)

    de Boer, Jan; Engelhardt, Dalit

    2016-12-01

    We revisit certain aspects of thermalization in 2D conformal field theory (CFT). In particular, we consider similarities and differences between the time dependence of correlation functions in various states in rational and non-rational CFTs. We also consider the distinction between global and local thermalization and explain how states obtained by acting with a diffeomorphism on the ground state can appear locally thermal, and we review why the time-dependent expectation value of the energy-momentum tensor is generally a poor diagnostic of global thermalization. Since all 2D CFTs have an infinite set of commuting conserved charges, generic initial states might be expected to give rise to a generalized Gibbs ensemble rather than a pure thermal ensemble at late times. We construct the holographic dual of the generalized Gibbs ensemble and show that, to leading order, it is still described by a Banados-Teitelboim-Zanelli black hole. The extra conserved charges, while rendering c <1 theories essentially integrable, therefore seem to have little effect on large-c conformal field theories.

  12. WFR-2D: an analytical model for PWAS-generated 2D ultrasonic guided wave propagation

    Science.gov (United States)

    Shen, Yanfeng; Giurgiutiu, Victor

    2014-03-01

    This paper presents WaveFormRevealer 2-D (WFR-2D), an analytical predictive tool for the simulation of 2-D ultrasonic guided wave propagation and interaction with damage. The design of structural health monitoring (SHM) systems and self-aware smart structures requires the exploration of a wide range of parameters to achieve best detection and quantification of certain types of damage. Such need for parameter exploration on sensor dimension, location, guided wave characteristics (mode type, frequency, wavelength, etc.) can be best satisfied with analytical models which are fast and efficient. The analytical model was constructed based on the exact 2-D Lamb wave solution using Bessel and Hankel functions. Damage effects were inserted in the model by considering the damage as a secondary wave source with complex-valued directivity scattering coefficients containing both amplitude and phase information from wave-damage interaction. The analytical procedure was coded with MATLAB, and a predictive simulation tool called WaveFormRevealer 2-D was developed. The wave-damage interaction coefficients (WDICs) were extracted from harmonic analysis of local finite element model (FEM) with artificial non-reflective boundaries (NRB). The WFR-2D analytical simulation results were compared and verified with full scale multiphysics finite element models and experiments with scanning laser vibrometer. First, Lamb wave propagation in a pristine aluminum plate was simulated with WFR-2D, compared with finite element results, and verified by experiments. Then, an inhomogeneity was machined into the plate to represent damage. Analytical modeling was carried out, and verified by finite element simulation and experiments. This paper finishes with conclusions and suggestions for future work.

  13. HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of apobec

    Energy Technology Data Exchange (ETDEWEB)

    Korber, Bette [Los Alamos National Laboratory; Bhattacharya, Tanmoy [Los Alamos National Laboratory; Giorgi, Elena [Los Alamos National Laboratory; Gaschen, B [Los Alamos National Laboratory; Daniels, M [Los Alamos National Laboratory

    2009-01-01

    The pattern of viral diversification in newly infected individuals provides information about the host environment and immune responses typically experienced by the newly transmitted virus. For example, sites that tend to evolve rapidly across multiple early-infection patients could be involved in enabling escape from common early immune responses, represent adaptation for rapid growth in a newly infected host, or reversion from less fit forms of the virus that were selected for immune escape in previous hosts. Here we investigated the diversification of HIV -I env coding sequences in 81 very early B SUbtype infections previously shown to have resulted from transmission or expansion of single viruses (n=78) or two closely related viruses (n=3). In these cases the sequence of the infecting virus can be estimated accurately, enabling inference of both the direction of substitutions as well as distinction between insertion and deletion events. By integrating information across multiple acutely infected hosts, we find evidence of adaptive evolution of HIV-1 envand identified a subset of codon sites that diversified more rapidly than can be explained by a model of neutral evolution. Of 24 such rapidly diversifying sites, 14 were either (i) clustered and embedded in CTL epitopes that were verified experimentally or predicted based on the individual's HLA or (ii) in a nucleotide context indicative of APOBEC mediated G-to-A substitutions, despite having excluded heavily hypermutated sequences prior to the analysis. In several cases, a rapidly evolving site was both embedded in an APOBEC motif and in a CTL epitope, suggesting that APOBEC may facilitate early immune escape. Ten rapidly diversifying sites could not be explained by CTL escape or APOBEC hypermutation, including the most frequently mutated site, in the fusion peptide of gp4l. We also examined the distribution, extent, and sequence context of insertions and deletions and provide evidence that the length

  14. Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients.

    Directory of Open Access Journals (Sweden)

    Matthias Merker

    Full Text Available Multidrug-resistant (MDR Mycobacterium tuberculosis complex (MTBC strains represent a major threat for tuberculosis (TB control. Treatment of MDR-TB patients is long and less effective, resulting in a significant number of treatment failures. The development of further resistances leads to extensively drug-resistant (XDR variants. However, data on the individual reasons for treatment failure, e.g. an induced mutational burst, and on the evolution of bacteria in the patient are only sparsely available. To address this question, we investigated the intra-patient evolution of serial MTBC isolates obtained from three MDR-TB patients undergoing longitudinal treatment, finally leading to XDR-TB. Sequential isolates displayed identical IS6110 fingerprint patterns, suggesting the absence of exogenous re-infection. We utilized whole genome sequencing (WGS to screen for variations in three isolates from Patient A and four isolates from Patient B and C, respectively. Acquired polymorphisms were subsequently validated in up to 15 serial isolates by Sanger sequencing. We determined eight (Patient A and nine (Patient B polymorphisms, which occurred in a stepwise manner during the course of the therapy and were linked to resistance or a potential compensatory mechanism. For both patients, our analysis revealed the long-term co-existence of clonal subpopulations that displayed different drug resistance allele combinations. Out of these, the most resistant clone was fixed in the population. In contrast, baseline and follow-up isolates of Patient C were distinguished each by eleven unique polymorphisms, indicating an exogenous re-infection with an XDR strain not detected by IS6110 RFLP typing. Our study demonstrates that intra-patient microevolution of MDR-MTBC strains under longitudinal treatment is more complex than previously anticipated. However, a mutator phenotype was not detected. The presence of different subpopulations might confound phenotypic and

  15. DEPTH-AVERAGED 2-D CALCULATION OF FLOW AND SEDIMENT TRANSPORT IN CURVED CHANNELS

    Institute of Scientific and Technical Information of China (English)

    Weiming WU; Sam S. Y. WANG

    2004-01-01

    The helical flow significantly affects the flow, sediment transport and morphological evolution in curved channels. A semi-empirical formula is proposed to determine the cross-stream distribution of the helical flow intensity in the developed regions of a channel bend. It is then used to evaluate the dispersion terms in the depth-averaged 2-D momentum equations and suspended-load transport equation as well as the bed-load transport angle, thus enhancing the depth-averaged 2-D model to account for the effect of helical flow. The tests in several experimental and field cases show that the enhanced depth-averaged 2-D model can much more reasonably predict the shifting of main flow from inner bank to outer bank, the erosion along outer bank and deposition along inner bank than the depth-averaged 2-D model without considering this effect.

  16. Some Aspects of 2D Integrability

    CERN Document Server

    Sedra, M B; Erguig, H; Zerouaoui, J

    2006-01-01

    We study the KdV and Burgers nonlinear systems and show in a consistent way that they can be mapped to each other through a strong requirement about their evolutions's flows to be connected. We expect that the established mapping between these particular systems should shed more light towards accomplishing some unification's mechanism for KdV hierarchy's integrable systems.

  17. The Co-Evolution of Asian Aquifers and Arsenic: How Understanding Sedimentary History can Help Predict Patterns of Arsenic Heterogeneity

    Science.gov (United States)

    Weinman, B. A.; Goodbred, S. L.; Savage, K.; Zheng, Y.; Radloff, K.; Singhvi, A.; Charlet, L.; Berg, M.; Eiche, E.; Cribb, W.; van Geen, A.

    2008-12-01

    After a decade of research, there is still no broad-scale understanding of why Asian aquifers support such heterogeneous distributions of groundwater arsenic. In countries like Bangladesh, Nepal, and Vietnam, it is often the case that wells spaced a few meters apart and drilled to the same depth have vastly different concentrations of dissolved arsenic (i.e., 100μg/L). While there is a general consensus that older Pleistocene sediments are typically depleted in arsenic relative to younger aquifer sediments, little is known about either the geological and geochemical evolution of these aquifers with time or the exact nature of their 3-dimensional stratigraphy. To better, and more broadly, understand why local groundwater arsenic patterns exhibit such heterogeneity, sedimentological investigations were undertaken in three arsenic-contaminated Asian villages, including: (1) a hyper-avulsive floodplain in Nepal's Terai, (2) an abandoned portion of the Brahmaputra River in Bangladesh, and (3) a meander bend along Vietnam's stable, fault-controlled Red River complex. Stratigraphic cross-sections, facies determinations, and luminescence dating of the aquifer sands along transects (~1 km long and ~15 m deep) from each of these villages indicate that the aquifer deposits are not uniform, that they vary in the subsurface, and that their depositional ages correspond to concentrations of arsenic dissolved in the groundwater. Comparisons of arsenic concentrations with aquifer age show that there is an inverse relationship, indicating that the age of the sediment does play a role in arsenic's availability and distribution. While there is still much to be learned about the exact mechanism(s) and rate(s) by which arsenic is being liberated, our investigations overall support a geologic model where much of the arsenic variance is explainable by stratigraphic variations over small distances (~10 meters) that results from the dynamic depositional conditions created by these active

  18. 2D Electrostatic Actuation of Microshutter Arrays

    Science.gov (United States)

    Burns, Devin E.; Oh, Lance H.; Li, Mary J.; Jones, Justin S.; Kelly, Daniel P.; Zheng, Yun; Kutyrev, Alexander S.; Moseley, Samuel H.

    2015-01-01

    An electrostatically actuated microshutter array consisting of rotational microshutters (shutters that rotate about a torsion bar) were designed and fabricated through the use of models and experiments. Design iterations focused on minimizing the torsional stiffness of the microshutters, while maintaining their structural integrity. Mechanical and electromechanical test systems were constructed to measure the static and dynamic behavior of the microshutters. The torsional stiffness was reduced by a factor of four over initial designs without sacrificing durability. Analysis of the resonant behavior of the microshutter arrays demonstrates that the first resonant mode is a torsional mode occurring around 3000 Hz. At low vacuum pressures, this resonant mode can be used to significantly reduce the drive voltage necessary for actuation requiring as little as 25V. 2D electrostatic latching and addressing was demonstrated using both a resonant and pulsed addressing scheme.

  19. 2-d Simulations of Test Methods

    DEFF Research Database (Denmark)

    Thrane, Lars Nyholm

    2004-01-01

    approach is presented by showing initial results from 2-d simulations of the empirical test methods slump flow and L-box. This method assumes a homogeneous material, which is expected to correspond to particle suspensions e.g. concrete, when it remains stable. The simulations have been carried out when......One of the main obstacles for the further development of self-compacting concrete is to relate the fresh concrete properties to the form filling ability. Therefore, simulation of the form filling ability will provide a powerful tool in obtaining this goal. In this paper, a continuum mechanical...... using both a Newton and Bingham model for characterisation of the rheological properties of the concrete. From the results, it is expected that both the slump flow and L-box can be simulated quite accurately when the model is extended to 3-d and the concrete is characterised according to the Bingham...

  20. Alignment free characterization of 2D gratings

    CERN Document Server

    Madsen, Morten Hannibal; Hansen, Poul-Erik; Jørgensen, Jan Friis

    2015-01-01

    Fast characterization of 2-dimensional gratings is demonstrated using a Fourier lens optical system and a differential optimization algorithm. It is shown that both the grating specific parameters such as the basis vectors and the angle between them and the alignment of the sample, such as the rotation of the sample around the x-, y-, and z-axis, can be deduced from a single measurement. More specifically, the lattice vectors and the angle between them have been measured, while the corrections of the alignment parameters are used to improve the quality of the measurement, and hence reduce the measurement uncertainty. Alignment free characterization is demonstrated on both a 2D hexagonal grating with a period of 700 nm and a checkerboard grating with a pitch of 3000 nm. The method can also be used for both automatic alignment and in-line characterization of gratings.

  1. Lie symmetries and 2D Material Physics

    CERN Document Server

    Belhaj, Adil

    2014-01-01

    Inspired from Lie symmetry classification, we establish a correspondence between rank two Lie symmetries and 2D material physics. The material unit cell is accordingly interpreted as the geometry of a root system. The hexagonal cells, appearing in graphene like models, are analyzed in some details and are found to be associated with A_2 and G_2 Lie symmetries. This approach can be applied to Lie supersymmetries associated with fermionic degrees of freedom. It has been suggested that these extended symmetries can offer a new way to deal with doping material geometries. Motivated by Lie symmetry applications in high energy physics, we speculate on a possible connection with (p,q) brane networks used in the string theory compactification on singular Calabi-Yau manifolds.

  2. Metrology for graphene and 2D materials

    Science.gov (United States)

    Pollard, Andrew J.

    2016-09-01

    The application of graphene, a one atom-thick honeycomb lattice of carbon atoms with superlative properties, such as electrical conductivity, thermal conductivity and strength, has already shown that it can be used to benefit metrology itself as a new quantum standard for resistance. However, there are many application areas where graphene and other 2D materials, such as molybdenum disulphide (MoS2) and hexagonal boron nitride (h-BN), may be disruptive, areas such as flexible electronics, nanocomposites, sensing and energy storage. Applying metrology to the area of graphene is now critical to enable the new, emerging global graphene commercial world and bridge the gap between academia and industry. Measurement capabilities and expertise in a wide range of scientific areas are required to address this challenge. The combined and complementary approach of varied characterisation methods for structural, chemical, electrical and other properties, will allow the real-world issues of commercialising graphene and other 2D materials to be addressed. Here, examples of metrology challenges that have been overcome through a multi-technique or new approach are discussed. Firstly, the structural characterisation of defects in both graphene and MoS2 via Raman spectroscopy is described, and how nanoscale mapping of vacancy defects in graphene is also possible using tip-enhanced Raman spectroscopy (TERS). Furthermore, the chemical characterisation and removal of polymer residue on chemical vapour deposition (CVD) grown graphene via secondary ion mass spectrometry (SIMS) is detailed, as well as the chemical characterisation of iron films used to grow large domain single-layer h-BN through CVD growth, revealing how contamination of the substrate itself plays a role in the resulting h-BN layer. In addition, the role of international standardisation in this area is described, outlining the current work ongoing in both the International Organization of Standardization (ISO) and the

  3. 2D Gridded Surface Data Value-Added Product

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Q [Lawrence Livermore National Laboratory; Xie, S [Lawrence Livermore National Laboratory

    2015-08-30

    This report describes the Atmospheric Radiation Measurement (ARM) Best Estimate (ARMBE) 2-dimensional (2D) gridded surface data (ARMBE2DGRID) value-added product. Spatial variability is critically important to many scientific studies, especially those that involve processes of great spatial variations at high temporal frequency (e.g., precipitation, clouds, radiation, etc.). High-density ARM sites deployed at the Southern Great Plains (SGP) allow us to observe the spatial patterns of variables of scientific interests. The upcoming megasite at SGP with its enhanced spatial density will facilitate the studies at even finer scales. Currently, however, data are reported only at individual site locations at different time resolutions for different datastreams. It is difficult for users to locate all the data they need and requires extra effort to synchronize the data. To address these problems, the ARMBE2DGRID value-added product merges key surface measurements at the ARM SGP sites and interpolates the data to a regular 2D grid to facilitate the data application.

  4. Reconstruction of a 2D seismic wavefield by seismic gradiometry

    Science.gov (United States)

    Maeda, Takuto; Nishida, Kiwamu; Takagi, Ryota; Obara, Kazushige

    2016-12-01

    We reconstructed a 2D seismic wavefield and obtained its propagation properties by using the seismic gradiometry method together with dense observations of the Hi-net seismograph network in Japan. The seismic gradiometry method estimates the wave amplitude and its spatial derivative coefficients at any location from a discrete station record by using a Taylor series approximation. From the spatial derivatives in horizontal directions, the properties of a propagating wave packet, including the arrival direction, slowness, geometrical spreading, and radiation pattern can be obtained. In addition, by using spatial derivatives together with free-surface boundary conditions, the 2D vector elastic wavefield can be decomposed into divergence and rotation components. First, as a feasibility test, we performed an analysis with a synthetic seismogram dataset computed by a numerical simulation for a realistic 3D medium and the actual Hi-net station layout. We confirmed that the wave amplitude and its spatial derivatives were very well-reproduced for period bands longer than 25 s. Applications to a real large earthquake showed that the amplitude and phase of the wavefield were well reconstructed, along with slowness vector. The slowness of the reconstructed wavefield showed a clear contrast between body and surface waves and regional non-great-circle-path wave propagation, possibly owing to scattering. Slowness vectors together with divergence and rotation decomposition are expected to be useful for determining constituents of observed wavefields in inhomogeneous media.

  5. Grazing incidence neutron diffraction from large scale 2D structures

    Energy Technology Data Exchange (ETDEWEB)

    Toperverg, B. P.; Felcher, G. P.; Metlushko, V. V.; Leiner, V.; Siebrecht, R.; Nikonov, O.

    2000-01-13

    The distorted wave Born approximation (DWBA) is applied to evaluate the diffraction pattern of neutrons (or X-rays) from a 2D array of dots deposited onto a dissimilar substrate. With the radiation impinging on the surface at a grazing incidence angle {alpha}, the intensities diffracted both in and out the plane of specular reflection are calculated as a function of the periodicity of the array, height and diameter of the dots. The results are presented in the form of diffracted intensity contours in a plane with coordinates {alpha} and {alpha}{prime}, the latter being the glancing angle of scattering. The optimization of the experimental conditions for polarized neutron experiments on submicron dots is discussed. The feasibility of such measurements is confirmed by a test experiment.

  6. Printable ink lenses, diffusers, and 2D gratings.

    Science.gov (United States)

    Ahmed, Rajib; Yetisen, Ali K; Khoury, Anthony El; Butt, Haider

    2017-01-07

    Advances in holography have led to applications including data storage, displays, security labels, and colorimetric sensors. However, existing top-down approaches for the fabrication of holographic devices are complex, expensive, and expertise dependent, limiting their use in practical applications. Here, ink-based holographic devices have been created for a wide range of applications in diffraction optics. A single pulse of a 3.5 ns Nd:YAG laser allowed selective ablation of ink to nanofabricate planar optical devices. The practicality of this method is demonstrated by fabricating ink-based diffraction gratings, 2D holographic patterns, optical diffusers, and Fresnel zone plate (FZP) lenses by using the ink. The fabrication processes were rationally designed using predictive computational modeling and the devices were fabricated within a few minutes demonstrating amenability for large scale printable optics through industrial manufacturing. It is anticipated that ink will be a promising diffraction optical material for the rapid printing of low-cost planar nanophotonic devices.

  7. Analysis of the IEA 2D test. 2D, 3D, steady or unsteady airflow?

    DEFF Research Database (Denmark)

    Cortes, Ines Olmedo; Nielsen, Peter V.

    The “IEA Annex 20 two-dimensional test case” was defined by proffesor Peter V. Nielsen (1990) and was originally considered two-dimensional and steady flow. However, some recent works considering the case as three dimensional have shown different solutions from the 2D case as well as different so...

  8. Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications

    Directory of Open Access Journals (Sweden)

    Jimenez-Perez Miriam I

    2012-02-01

    Full Text Available Abstract Background Cervical cancer represents the third most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths in women worldwide. Natural killer (NK cells play an important role in the defense against viruses, intracellular bacteria and tumors. NKG2D, an activating receptor on NK cells, recognizes MHC class I chain-related molecules, such as MICA/B and members of the ULBP/RAET1 family. Tumor-derived soluble NKG2D-ligands have been shown to down-modulate the expression of NKG2D on NK cells. In addition to the down-modulation induced by soluble NKG2D-ligands, it has recently been described that persistent cell-cell contact can also down-modulate NKG2D expression. The goal of this study was to determine whether the NKG2D receptor is down-modulated by cell-cell contact with cervical cancer cells and whether this down-modulation might be associated with changes in NK cell activity. Results We demonstrate that NKG2D expressed on NKL cells is down-modulated by direct cell contact with cervical cancer cell lines HeLa, SiHa, and C33A, but not with non-tumorigenic keratinocytes (HaCaT. Moreover, this down-modulation had functional implications. We found expression of NKG2D-ligands in all cervical cancer cell lines, but the patterns of ligand distribution were different in each cell line. Cervical cancer cell lines co-cultured with NKL cells or fresh NK cells induced a marked diminution of NKG2D expression on NKL cells. Additionally, the cytotoxic activity of NKL cells against K562 targets was compromised after co-culture with HeLa and SiHa cells, while co-culture with C33A increased the cytotoxic activity of the NKL cells. Conclusions Our results suggest that differential expression of NKG2D-ligands in cervical cancer cell lines might be associated with the down-modulation of NKG2D, as well as with changes in the cytotoxic activity of NKL cells after cell-cell contact with the tumor cells.

  9. Seepage Analysis of Upper Gotvand Dam Concerning Gypsum Karstification (2D and 3D Approaches)

    DEFF Research Database (Denmark)

    Sadrekarimi, Jamshid; Kiyani, Majid; Fakhri, Behnam;

    2011-01-01

    Upper Gotvand Dam is constructed on the Karun River at the south west of Iran. In this paper, 2D and 3D models of the dam together with the foundation and abutments were established, and several seepage analyses were carried out. Then, the gypsum veins that are scattered throughout the foundation...... ground were included in the models, and the seepage pattern, considering the dissolution law of gypsum, was analyzed. It was disclosed that the discharge fluxes obtained from 2D and 3D analyses are not similar, and the discharge flux in 3D model is about four times that of the 2D model. Also, the 3D...... model locates the phreatic surface somewhat higher than the 2D model. This means that the 2D model estimates lower pore water pressure pattern in comparison with the 3D model. These may be attributed to the fact that with 2D model the lateral components of vectors of seepage velocity are ignored...

  10. Analysis list: Kmt2d [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Kmt2d Adipocyte,Pluripotent stem cell + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Kmt2d....1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Kmt2d.5.tsv http://dbarchiv...e.biosciencedbc.jp/kyushu-u/mm9/target/Kmt2d.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Kmt2d....Adipocyte.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Kmt2d.Pluripo

  11. Analysis list: KMT2D [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available KMT2D Blood,Digestive tract + hg19 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/KM...T2D.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/KMT2D.5.tsv http://dbarchive.biosc...iencedbc.jp/kyushu-u/hg19/target/KMT2D.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/KMT2D.Blo...od.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/KMT2D.Digestive_tract

  12. Ion Transport in 2-D Graphene Nanochannels

    Science.gov (United States)

    Xie, Quan; Foo, Elbert; Duan, Chuanhua

    2015-11-01

    Graphene membranes have recently attracted wide attention due to its great potential in water desalination and selective molecular sieving. Further developments of these membranes, including enhancing their mass transport rate and/or molecular selectivity, rely on the understanding of fundamental transport mechanisms through graphene membranes, which has not been studied experimentally before due to fabrication and measurement difficulties. Herein we report the fabrication of the basic constituent of graphene membranes, i.e. 2-D single graphene nanochannels (GNCs) and the study of ion transport in these channels. A modified bonding technique was developed to form GNCs with well-defined geometry and uniform channel height. Ion transport in such GNCs was studied using DC conductance measurement. Our preliminary results showed that the ion transport in GNCs is still governed by surface charge at low concentrations (10-6M to 10-4M). However, GNCs exhibits much higher ionic conductances than silica nanochannels with the same geometries in the surface-charge-governed regime. This conductance enhancement can be attributed to the pre-accumulation of charges on graphene surfaces. The work is supported by the Faculty Startup Fund (Boston University, USA).

  13. 2D DIGITAL SIMPLIFIED FLOW VALVE

    Institute of Scientific and Technical Information of China (English)

    Ruan Jian; Li Sheng; Pei Xiang; Burton R; Ukrainetz P; Bitner D

    2004-01-01

    The 2D digital simplified flow valve is composed of a pilot-operated valve designed with both rotary and linear motions of a single spool,and a stepper motor under continual control.How the structural parameters affect the static and dynamic characteristics of the valve is first clarified and a criterion for stability is presented.Experiments are designed to test the performance of the valve.It is necessary to establish a balance between the static and dynamic characteristics in deciding the structural parameters.Nevertheless,it is possible to maintain the dynamic response at a fairly high level,while keeping the leakage of the pilot stage at an acceptable level.One of the features of the digital valve is stage control.In stage control the nonlinearities,such as electromagnetic saturation and hysteresis,are greatly reduced.To a large extent the dynamic response of the valve is decided by the executing cycle of the control algorithm.

  14. Competing coexisting phases in 2D water

    Science.gov (United States)

    Zanotti, Jean-Marc; Judeinstein, Patrick; Dalla-Bernardina, Simona; Creff, Gaëlle; Brubach, Jean-Blaise; Roy, Pascale; Bonetti, Marco; Ollivier, Jacques; Sakellariou, Dimitrios; Bellissent-Funel, Marie-Claire

    2016-05-01

    The properties of bulk water come from a delicate balance of interactions on length scales encompassing several orders of magnitudes: i) the Hydrogen Bond (HBond) at the molecular scale and ii) the extension of this HBond network up to the macroscopic level. Here, we address the physics of water when the three dimensional extension of the HBond network is frustrated, so that the water molecules are forced to organize in only two dimensions. We account for the large scale fluctuating HBond network by an analytical mean-field percolation model. This approach provides a coherent interpretation of the different events experimentally (calorimetry, neutron, NMR, near and far infra-red spectroscopies) detected in interfacial water at 160, 220 and 250 K. Starting from an amorphous state of water at low temperature, these transitions are respectively interpreted as the onset of creation of transient low density patches of 4-HBonded molecules at 160 K, the percolation of these domains at 220 K and finally the total invasion of the surface by them at 250 K. The source of this surprising behaviour in 2D is the frustration of the natural bulk tetrahedral local geometry and the underlying very significant increase in entropy of the interfacial water molecules.

  15. Intermittency in 2D soap film turbulence

    CERN Document Server

    Cerbus, R T

    2013-01-01

    The Reynolds number dependency of intermittency for 2D turbulence is studied in a flowing soap film. The Reynolds number used here is the Taylor microscale Reynolds number R_{\\lambda}, which ranges from 20 to 800. Strong intermittency is found for both the inverse energy and direct enstrophy cascades as measured by (a) the pdf of velocity differences P(\\delta u(r)) at inertial scales r, (b) the kurtosis of P(\\partial_x u), and (c) the scaling of the so-called intermittency exponent \\mu, which is zero if intermittency is absent. Measures (b) and (c) are quantitative, while (a) is qualitative. These measurements are in disagreement with some previous results but not all. The velocity derivatives are nongaussian at all R_{\\lambda} but show signs of becoming gaussian as R_{\\lambda} increases beyond the largest values that could be reached. The kurtosis of P(\\delta u(r)) at various r indicates that the intermittency is scale dependent. The structure function scaling exponents also deviate strongly from the Kraichn...

  16. 2-D blood vector velocity estimation using a phase shift estimator

    DEFF Research Database (Denmark)

    Udesen, Jesper

    2006-01-01

    In this PhD thesis a method for 2-D blood velocity estimation called \\textit{the transverse oscillation method} (TO) is investigated. The thesis is divided into two parts. In the first part the basic principles in conventional 1-D flow estimation are described, and the state of the art for 2-D...... velocity estimation is discussed. The TO method is introduced, and the basic theory behind the method is explained. This includes the creation of the acoustic fields, beamforming, echo-canceling and the velocity estimator. In the second part of the thesis the eight papers produced during this PhD project...... when the angle between the blood and the ultrasound beam is above $50^\\circ$. Furthermore, the TO method is tested in-vivo where the scannings are performed by skilled sonographers. The in-vivo scannings resulted in a sequence of 2-D vector CFM images which showed 2-D flow patterns in the bifurcation...

  17. Similar patterns of rDNA evolution in synthetic and recently formed natural populations of Tragopogon (Asteraceae allotetraploids

    Directory of Open Access Journals (Sweden)

    Soltis Pamela S

    2010-09-01

    homeologous rRNA gene copies occurred in both synthetic and natural populations of Tragopogon allopolyploids. The extent of these rDNA changes was generally higher in natural populations than in the synthetic lines. We hypothesize that locus-specific and chromosomal changes in early generations of allopolyploids may influence patterns of rDNA evolution in later generations.

  18. Physical Parameters of a Flare Derived from Multi-line 2D Spectroscopy

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Time series of 2D spectra of Hα and CaII λ8542 for a flare of 1999 December 22 are obtained and analyzed with a new fitting technique. The method we proposed can simultaneously yield the four parameters: the line source function, the optical thickness at line center, the line-of-sight velocity and the Doppler width. We present the spatial distributions of the physical parameters and their temporal evolutions determined from the 2D spectra. Our results are consistent with the general picture predicted by the flare dynamic models.

  19. Coalescence of Anderson-localized modes at an exceptional point in 2D random media

    CERN Document Server

    Bachelard, Nicolas; Arlandis, Julien; Touzani, Rachid; Sebbah, Patrick

    2014-01-01

    In non-hermitian systems, the particular position at which two eigenstates coalesce under a variation of a parameter in the complex plane is called an exceptional point. A non-perturbative theory is proposed which describes the evolution of modes in 2D open dielectric systems when permittivity distribution is modified. We successfully test this theory in a 2D disordered system to predict the position in the parameter space of the exceptional point between two Anderson-localized states. We observe that the accuracy of the prediction depends on the number of localized states accounted for. Such an exceptional point is experimentally accessible in practically relevant disordered photonic systems

  20. 2D to 3D transition of polymeric carbon nitride nanosheets

    Energy Technology Data Exchange (ETDEWEB)

    Chamorro-Posada, Pedro [Dpto. de Teoría de la Señal y Comunicaciones e IT, Universidad de Valladolid, ETSI Telecomunicación, Paseo Belén 15, 47011 Valladolid (Spain); Vázquez-Cabo, José [Dpto. de Teoría de la Señal y Comunicaciones, Universidad de Vigo, ETSI Telecomunicación, Lagoas Marcosende s/n, Vigo (Spain); Sánchez-Arévalo, Francisco M. [Instituto de Investigaciones en Materiales (IIM), Universidad Nacional Autónoma de México, Apdo. Postal 70–360, Cd. Universitaria, México D.F. 04510 (Mexico); Martín-Ramos, Pablo [Dpto. de Teoría de la Señal y Comunicaciones e IT, Universidad de Valladolid, ETSI Telecomunicación, Paseo Belén 15, 47011 Valladolid (Spain); Laboratorio de Materiales Avanzados (Advanced Materials Laboratory) ETSIIAA, Universidad de Valladolid, Avenida de Madrid 44, 34004 Palencia (Spain); Martín-Gil, Jesús; Navas-Gracia, Luis M. [Laboratorio de Materiales Avanzados (Advanced Materials Laboratory) ETSIIAA, Universidad de Valladolid, Avenida de Madrid 44, 34004 Palencia (Spain); Dante, Roberto C., E-mail: rcdante@yahoo.com [Laboratorio de Materiales Avanzados (Advanced Materials Laboratory) ETSIIAA, Universidad de Valladolid, Avenida de Madrid 44, 34004 Palencia (Spain)

    2014-11-15

    The transition from a prevalent turbostratic arrangement with low planar interactions (2D) to an array of polymeric carbon nitride nanosheets with stronger interplanar interactions (3D), occurring for samples treated above 650 °C, was detected by terahertz-time domain spectroscopy (THz-TDS). The simulated 3D material made of stacks of shifted quasi planar sheets composed of zigzagged polymer ribbons, delivered a XRD simulated pattern in relatively good agreement with the experimental one. The 2D to 3D transition was also supported by the simulation of THz-TDS spectra obtained from quantum chemistry calculations, in which the same broad bands around 2 THz and 1.5 THz were found for 2D and 3D arrays, respectively. This transition was also in accordance with the tightening of the interplanar distance probably due to an interplanar π bond contribution, as evidenced also by a broad absorption around 2.6 eV in the UV–vis spectrum, which appeared in the sample treated at 650 °C, and increased in the sample treated at 700 °C. The band gap was calculated for 1D and 2D cases. The value of 3.374 eV for the 2D case is, within the model accuracy and precision, in a relative good agreement with the value of 3.055 eV obtained from the experimental results. - Graphical abstract: 2D lattice mode vibrations and structural changes correlated with the so called “2D to 3D transition”. - Highlights: • A 2D to 3D transition has been detected for polymeric carbon nitride. • THz-TDS allowed us to discover and detect the 2D to 3D transition of polymeric carbon nitride. • We propose a structure for polymeric carbon nitride confirming it with THz-TDS.

  1. Power loss analysis of n-PASHA cells validated by 2D simulations

    Energy Technology Data Exchange (ETDEWEB)

    Janssen, G.J.M.; Gutjahr, A.; Burgers, A.R.; Saynova, D.S.; Cesar, I.; Romijn, I.G.

    2013-10-15

    To reach >21% efficiency for the n-Pasha (passivated all sides H-pattern) cell of ECN, reliable power-loss analyses are essential. A power-loss analysis is presented that is based on experimental data but validated and completed by 2D simulations. The analysis is used to identify the key factors that will contribute most to achieving >21% efficiency.

  2. Synthesis of 2D Hexagonal Mesoporous Silica Using Amino Acid-based Surfactant Templating

    Directory of Open Access Journals (Sweden)

    Xu Hailan

    2016-01-01

    Full Text Available Ordered 2D hexagonal and parallel arranged pore channel mesoporous silica materials with homogeneous size and spherical shape have been synthesized by using amino acid-based surfactant templating, their ordered mesostructures were characterized by infrared spectroscopy, X-ray diffraction patterns (XRD, scanning electron microscopy (SEM, transmission electron microscopy (TEM and nitrogen sorption analysis.

  3. Analysis list: Mef2d [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Mef2d Muscle + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Mef2d.1.ts...v http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Mef2d.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Mef2d....10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Mef2d.Muscle.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Muscle.gml ...

  4. Stability Test for 2-D Continuous-Discrete Systems

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Models of 2-D continuous-discrete systems are introduced, which can be used to describe some complex systems. Different from classical 2-D continuous systems or 2-D discrete systems, the asymptotic stability of the continuous-discrete systems is determined by Hurwitz-Schur stability (hybrid one) of 2-D characteristic polynomials of the systems. An algebraic algorithm with simpler test procedure for Hurwitz-Schur stability test of 2-D polynomials is developed. An example to illustrate the applications of the test approach is provided.

  5. Pharm GKB: CYP2D6 [PharmGKB

    Lifescience Database Archive (English)

    Full Text Available el for vortioxetine and CYP2D6 FDA Label for acetaminophen,tramadol and CYP2D6 FDA Label for dextromethorphan... Label for vortioxetine and CYP2D6 European Medicines Agency (EMA) Label for dextromethorphan,quinidine and ...ore of this label. Read more. last updated 10/25/2013 FDA Label for dextromethorphan, quinidine and CYP2D6 O...of NUEDEXTA is a CYP2D6 inhibitor used to increase the plasma availability of dextromethorphan, which is met... 05/02/2014 European Medicines Agency (EMA) Label for dextromethorphan, quinidine

  6. 3D/2D Registration of medical images

    OpenAIRE

    Tomaževič, D.

    2008-01-01

    The topic of this doctoral dissertation is registration of 3D medical images to corresponding projective 2D images, referred to as 3D/2D registration. There are numerous possible applications of 3D/2D registration in image-aided diagnosis and treatment. In most of the applications, 3D/2D registration provides the location and orientation of the structures in a preoperative 3D CT or MR image with respect to intraoperative 2D X-ray images. The proposed doctoral dissertation tries to find origin...

  7. Genome-wide analysis reveals diverged patterns of codon bias, gene expression, and rates of sequence evolution in picea gene families.

    Science.gov (United States)

    De La Torre, Amanda R; Lin, Yao-Cheng; Van de Peer, Yves; Ingvarsson, Pär K

    2015-03-05

    The recent sequencing of several gymnosperm genomes has greatly facilitated studying the evolution of their genes and gene families. In this study, we examine the evidence for expression-mediated selection in the first two fully sequenced representatives of the gymnosperm plant clade (Picea abies and Picea glauca). We use genome-wide estimates of gene expression (>50,000 expressed genes) to study the relationship between gene expression, codon bias, rates of sequence divergence, protein length, and gene duplication. We found that gene expression is correlated with rates of sequence divergence and codon bias, suggesting that natural selection is acting on Picea protein-coding genes for translational efficiency. Gene expression, rates of sequence divergence, and codon bias are correlated with the size of gene families, with large multicopy gene families having, on average, a lower expression level and breadth, lower codon bias, and higher rates of sequence divergence than single-copy gene families. Tissue-specific patterns of gene expression were more common in large gene families with large gene expression divergence than in single-copy families. Recent family expansions combined with large gene expression variation in paralogs and increased rates of sequence evolution suggest that some Picea gene families are rapidly evolving to cope with biotic and abiotic stress. Our study highlights the importance of gene expression and natural selection in shaping the evolution of protein-coding genes in Picea species, and sets the ground for further studies investigating the evolution of individual gene families in gymnosperms.

  8. Climate and evolution: implications of some extinction patterns in African and European Machairodontine Cats of the Plio-Pleistocene

    Directory of Open Access Journals (Sweden)

    Antón, M.

    1998-12-01

    Full Text Available Estudios recientes sobre las correlaciones entre cambios climáticos globales y la evolución de la biota del Plio-Pleistoceno Africano han revelado aparentes discrepancias entre las fechas y la significación de eventos registrados en distintas fuentes. Las diferencias mas notables se refieren a un importante cambio en la proporción de isótopos de oxígeno marinas hace 2,5 millones de años, y a la posibilidad de una transición biótica relacionada causalmente con dicho cambio. Cambios en la vegetación detectados a través de los valores de isótopos estables en los paleosuelos sugieren que el principal cambio hacia una vegetación mas abierta ocurrió mas tarde, hace ∼1,7 millones de años. Nosotros estudiamos el problema refiriendonos en particular a los eventos de hace 1,7 millones de años, y a la extinción en Africa de los félidos con dientes de sable que se produce poco después, puesto que las extinciones de taxones euritópicos como estos probablemente señala cambios significativos en las condiciones ambientales. Nosotros comparamos el patrón de dichas extinciones con los de taxones semejantes 0 idénticos, en Eurasia y América, y sugerimos que en cada caso hay claros indicios de importantes cambios ambientales. Es probable que los cambios en la vegetación de Africa registrados hace ∼1,7 millones de años representen una respuesta en el medio terrestre alas cambios climáticos globales reflejados en el registro marino hace ∼1,9 millones de años.Recent discussions of correlations between global climatic change and evolution of the African Plio-Pleistocene biota have revealed apparent discrepancies between the timing and significance of events recorded in different data sets. The most notable differences have occurred in relation to a major shift in the ratio of marine oxygen isotopes by 2.5 myr and claims for a causally related transition in the biota. Vegetational changes recorded in palaeosol stable isotope

  9. CYP2D7 sequence variation interferes with TaqMan CYP2D6*15 and *35 genotyping

    Directory of Open Access Journals (Sweden)

    Amanda K Riffel

    2016-01-01

    Full Text Available TaqMan™ genotyping assays are widely used to genotype CYP2D6, which encodes a major drug metabolizing enzyme. Assay design for CYP2D6 can be challenging owing to the presence of two pseudogenes, CYP2D7 and CYP2D8, structural and copy number variation and numerous single nucleotide polymorphisms (SNPs some of which reflect the wild-type sequence of the CYP2D7 pseudogene. The aim of this study was to identify the mechanism causing false positive CYP2D6*15 calls and remediate those by redesigning and validating alternative TaqMan genotype assays. Among 13,866 DNA samples genotyped by the CompanionDx® lab on the OpenArray platform, 70 samples were identified as heterozygotes for 137Tins, the key SNP of CYP2D6*15. However, only 15 samples were confirmed when tested with the Luminex xTAG CYP2D6 Kit and sequencing of CYP2D6-specific long range (XL-PCR products. Genotype and gene resequencing of CYP2D6 and CYP2D7-specific XL-PCR products revealed a CC>GT dinucleotide SNP in exon 1 of CYP2D7 that reverts the sequence to CYP2D6 and allows a TaqMan assay PCR primer to bind. Because CYP2D7 also carries a Tins, a false-positive mutation signal is generated. This CYP2D7 SNP was also responsible for generating false-positive signals for rs769258 (CYP2D6*35 which is also located in exon 1. Although alternative CYP2D6*15 and *35 assays resolved the issue, we discovered a novel CYP2D6*15 subvariant in one sample that carries additional SNPs preventing detection with the alternate assay. The frequency of CYP2D6*15 was 0.1% in this ethnically diverse U.S. population sample. In addition, we also discovered linkage between the CYP2D7 CC>GT dinucleotide SNP and the 77G>A (rs28371696 SNP of CYP2D6*43. The frequency of this tentatively functional allele was 0.2%. Taken together, these findings emphasize that regardless of how careful genotyping assays are designed and evaluated before being commercially marketed, rare or unknown SNPs underneath primer and/or probe

  10. Time scales of pattern evolution from cross-spectrum analysis of advanced very high resolution radiometer and coastal zone color scanner imagery

    Science.gov (United States)

    Denman, Kenneth L.; Abbott, Mark R.

    1994-01-01

    We have selected square subareas (110 km on a side) from coastal zone color scanner (CZCS) and advanced very high resolution radiometer (AVHRR) images for 1981 in the California Current region off northern California for which we could identify sequences of cloud-free data over periods of days to weeks. We applied a two-dimensional fast Fourier transformation to images after median filtering, (x, y) plane removal, and cosine tapering. We formed autospectra and coherence spectra as functions of a scalar wavenumber. Coherence estimates between pairs of images were plotted against time separation between images for several wide wavenumber bands to provide a temporal lagged coherence function. The temporal rate of loss of correlation (decorrelation time scale) in surface patterns provides a measure of the rate of pattern change or evolution as a function of spatial dimension. We found that patterns evolved (or lost correlation) approximately twice as rapidly in upwelling jets as in the 'quieter' regions between jets. The rapid evolution of pigment patterns (lifetime of about 1 week or less for scales of 50-100 km) ought to hinder biomass transfer to zooplankton predators compared with phytoplankton patches that persist for longer times. We found no significant differences between the statistics of CZCS and AVHRR images (spectral shape or rate of decorrelation). In addition, in two of the three areas studied, the peak correlation between AVHRR and CZCS images from the same area occurred at zero lag, indicating that the patterns evolved simutaneously. In the third area, maximum coherence between thermal and pigment patterns occurred when pigment images lagged thermal images by 1-2 days, mirroring the expected lag of high pigment behind low temperatures (and high nutrients) in recently upwelled water. We conclude that in dynamic areas such as coastal upwelling systems, the phytoplankton cells (identified by pigment color patterns) behave largely as passive scalars at the

  11. Backscattering in a 2D topological insulator and the conductivity of a 2D strip

    Science.gov (United States)

    Magarill, L. I.; Entin, M. V.

    2015-01-01

    A strip of the 2D HgTe topological insulator is studied. The same-spin edge states in an ideal system propagate in opposite directions on different sides of the strip and do not mix by tunneling. Impurities, edge irregularities, and phonons produce transitions between the counterpropagating edge states on different edges. This backscattering determines the conductivity of an infinitely long strip. The conductivity at finite temperature is determined in the framework of the kinetic equation. It is found that the conductivity exponentially grows with the strip width. In the same approximation the nonlocal resistance coefficients of a four-terminal strip are found.

  12. Digit ratio (2D:4D), lateral preferences, and performance in fencing.

    Science.gov (United States)

    Voracek, Martin; Reimer, Barbara; Ertl, Clara; Dressler, Stefan G

    2006-10-01

    The second to fourth digit ratio (2D:4D) is a sexually dimorphic trait (men tend to have lower values than women) and a likely biomarker for the organizational (permanent) effects of prenatal androgens on the human brain and body. Prenatal testosterone, as reflected by 2D:4D, has many extragenital effects, including its relevance for the formation of an efficient cardiovascular system. Previous research, reviewed here, has therefore investigated possible associations of 2D:4D with sport performance. Several studies found more masculinized digit ratio patterns (low 2D:4D values or a negative right-minus-left difference in 2D:4D) to be related to high performance in running, soccer, and skiing. The present research tested this hypothesis in a sample of 54 tournament fencers, predominantly from Austria. For men, negative right-left differences in 2D:4D corresponded significantly to better current as well as highest national fencing rankings, independent of training intensity and fencing experience. The mean 2D:4D values of these fencers were significantly lower and the proportion of left-handers was elevated relative to the local general population. For the right hand, the ratio was somewhat lower in male sabre fencers than in male epée and foil fencers combined and significantly lower in left-handed compared to right-handed fencers. Although nonsignificant due to low statistical power, effect sizes suggested that crossed versus congruent hand-eye and hand-foot preferences might also be related to fencing performance. The present findings add to the evidence that 2D:4D might be a performance indicator for men across a variety of sports.

  13. Streamflow recession patterns can help unravel the role of climate and humans in landscape co-evolution

    Science.gov (United States)

    Bogaart, Patrick W.; van der Velde, Ype; Lyon, Steve W.; Dekker, Stefan C.

    2016-04-01

    Traditionally, long-term predictions of river discharges and their extremes include constant relationships between landscape properties and model parameters. However, due to the co-evolution of many landscape properties more sophisticated methods are necessary to quantify future landscape-hydrological model relationships. As a first step towards such an approach we use the Brutsaert and Nieber (1977) analysis method to characterize streamflow recession behaviour of ≈ 200 Swedish catchments within the context of global change and landscape co-evolution. Results suggest that the Brutsaert-Nieber parameters are strongly linked to the climate, soil, land use, and their interdependencies. Many catchments show a trend towards more non-linear behaviour, meaning not only faster initial recession but also slower recession towards base flow. This trend has been found to be independent from climate change. Instead, we suggest that land cover change, both natural (restoration of natural soil profiles in forested areas) and anthropogenic (reforestation and optimized water management), is probably responsible. Both change types are characterised by system adaptation and change, towards more optimal ecohydrological conditions, suggesting landscape co-evolution is at play. Given the observed magnitudes of recession changes during the past 50 years, predictions of future river discharge critically need to include the effects of landscape co-evolution. The interconnections between the controls of land cover and climate on river recession behaviour, as we have quantified in this paper, provide first-order handles to do so.

  14. Streamflow recession patterns can help unravel the role of climate and humans in landscape co-evolution

    NARCIS (Netherlands)

    Bogaart, Patrick W.; Van Der Velde, Ype; Lyon, Steve W.; Dekker, Stefan C.

    2016-01-01

    Traditionally, long-term predictions of river discharges and their extremes include constant relationships between landscape properties and model parameters. However, due to the co-evolution of many landscape properties more sophisticated methods are necessary to quantify future landscape-hydrologic

  15. Residual lens effects in 2D mode of auto-stereoscopic lenticular-based switchable 2D/3D displays

    Science.gov (United States)

    Sluijter, M.; IJzerman, W. L.; de Boer, D. K. G.; de Zwart, S. T.

    2006-04-01

    We discuss residual lens effects in multi-view switchable auto-stereoscopic lenticular-based 2D/3D displays. With the introduction of a switchable lenticular, it is possible to switch between a 2D mode and a 3D mode. The 2D mode displays conventional content, whereas the 3D mode provides the sensation of depth to the viewer. The uniformity of a display in the 2D mode is quantified by the quality parameter modulation depth. In order to reduce the modulation depth in the 2D mode, birefringent lens plates are investigated analytically and numerically, by ray tracing. We can conclude that the modulation depth in the 2D mode can be substantially decreased by using birefringent lens plates with a perfect index match between lens material and lens plate. Birefringent lens plates do not disturb the 3D performance of a switchable 2D/3D display.

  16. The evolution of the induction air conditioning. For any use the optimal flow patterns; Die Evolution der Induktionsklimaanlage. Fuer jede Nutzung die optimalen Stroemungsformen

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Ralf; Roth, Hans Werner [LTG Aktiengesellschaft, Stuttgart (Germany)

    2011-07-01

    Why are induction air conditioning systems hardly remediated in the same system and rarely incorporated in new office buildings? Perhaps it is also due to a lack of information on how to build and operate induction units according to current knowledge in order to meet the enhanced requirements for high comfort and low energy consumption. The authors of the contribution under consideration present a new concept according to an energy-saving and sustainable implementation of the basic principle 'induction' in a building by means of equipment modules and flow patterns on very different utilization and expense.

  17. Shared human-chimpanzee pattern of perinatal femoral shaft morphology and its implications for the evolution of hominin locomotor adaptations.

    Directory of Open Access Journals (Sweden)

    Naoki Morimoto

    Full Text Available BACKGROUND: Acquisition of bipedality is a hallmark of human evolution. How bipedality evolved from great ape-like locomotor behaviors, however, is still highly debated. This is mainly because it is difficult to infer locomotor function, and even more so locomotor kinematics, from fossil hominin long bones. Structure-function relationships are complex, as long bone morphology reflects phyletic history, developmental programs, and loading history during an individual's lifetime. Here we discriminate between these factors by investigating the morphology of long bones in fetal and neonate great apes and humans, before the onset of locomotion. METHODOLOGY/PRINCIPAL FINDINGS: Comparative morphometric analysis of the femoral diaphysis indicates that its morphology reflects phyletic relationships between hominoid taxa to a greater extent than taxon-specific locomotor adaptations. Diaphyseal morphology in humans and chimpanzees exhibits several shared-derived features, despite substantial differences in locomotor adaptations. Orangutan and gorilla morphologies are largely similar, and likely represent the primitive hominoid state. CONCLUSIONS/SIGNIFICANCE: These findings are compatible with two possible evolutionary scenarios. Diaphyseal morphology may reflect retained adaptive traits of ancestral taxa, hence human-chimpanzee shared-derived features may be indicative of the locomotor behavior of our last common ancestor. Alternatively, diaphyseal morphology might reflect evolution by genetic drift (neutral evolution rather than selection, and might thus be more informative about phyletic relationships between taxa than about locomotor adaptations. Both scenarios are consistent with the hypothesis that knuckle-walking in chimpanzees and gorillas resulted from convergent evolution, and that the evolution of human bipedality is unrelated to extant great ape locomotor specializations.

  18. Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49.

    Directory of Open Access Journals (Sweden)

    Hua Cai

    Full Text Available The CYP2D family members are instrumental in the metabolism of 20-25% of commonly prescribed drugs. Although many CYP2D isoforms have been well characterized in other animal models, research concerning the chicken CYP2Ds is limited. In this study, a cDNA encoding a novel CYP2D enzyme (CYP2D49 was cloned from the chicken liver for the first time. The CYP2D49 cDNA contained an open reading frame of 502 amino acids that shared 52%-57% identities with other CYP2Ds. The gene structure and neighboring genes of CYP2D49 are conserved and similar to those of human CYP2D6. Additionally, similar to human CYP2D6, CYP2D49 is un-inducible in the liver and expressed predominantly in the liver, kidney and small intestine, with detectable levels in several other tissues. Metabolic assays of the CYP2D49 protein heterologously expressed in E. coli and Hela cells indicated that CYP2D49 metabolized the human CYP2D6 substrate, bufuralol, but not debrisoquine. Moreover, quinidine, a potent inhibitor of human CYP2D6, only inhibited the bufuralol 1'-hydroxylation activity of CYP2D49 to a negligible degree. All these results indicated that CYP2D49 had functional characteristics similar to those of human CYP2D6 but measurably differed in the debrisoquine 4'-hydroxylation and quinidine inhibitory profile. Further structure-function investigations that employed site-directed mutagenesis and circular dichroism spectroscopy identified the importance of Val-126, Glu-222, Asp-306, Phe-486 and Phe-488 in keeping the enzymatic activity of CYP2D49 toward bufuralol as well as the importance of Asp-306, Phe-486 and Phe-488 in maintaining the conformation of CYP2D49 protein. The current study is only the first step in characterizing the metabolic mechanism of CYP2D49; further studies are still required.

  19. Combining the switched-beam and beam-steering capabilities in a 2-D phased array antenna system

    Science.gov (United States)

    Tsai, Yi-Che; Chen, Yin-Bing; Hwang, Ruey-Bing

    2016-01-01

    This paper presents the development, fabrication, and measurement of a novel beam-forming system consisting of 16 subarray antennas, each containing four aperture-coupled patch antennas, and the application of this system in smart wireless communication systems. The beam patterns of each of the subarray antennas can be switched toward one of nine zones over a half space by adjusting the specific phase delay angles among the four antenna elements. Furthermore, when all subarrays are pointed at the same zone, slightly continuous beam steering in around 1° increments can be achieved by dynamically altering the progressive phase delay angle among the subarrays. Phase angle calibration was implemented by coupling each transmitter output and down converter into the in-phase/quadrature baseband to calculate the correction factor to the weight. In addition, to validate the proposed concepts and the fabricated 2-D phased array antenna system, this study measured the far-field radiation patterns of the aperture-coupled patch array integrated with feeding networks and a phase-calibration system to carefully verify its spatially switched-beam and beam-steering characteristics at a center frequency of 2.4 GHz which can cover the industrial, scientific, and medical band and some long-term evolution applications. In addition, measured results were compared with calculated results, and agreement between them was observed.

  20. 2D wave-front shaping in optical superlattices using nonlinear volume holography.

    Science.gov (United States)

    Yang, Bo; Hong, Xu-Hao; Lu, Rong-Er; Yue, Yang-Yang; Zhang, Chao; Qin, Yi-Qiang; Zhu, Yong-Yuan

    2016-07-01

    Nonlinear volume holography is employed to realize arbitrary wave-front shaping during nonlinear processes with properly designed 2D optical superlattices. The concept of a nonlinear polarization wave in nonlinear volume holography is investigated. The holographic imaging of irregular patterns was performed using 2D LiTaO3 crystals with fundamental wave propagating along the spontaneous polarization direction, and the results agree well with the theoretical predictions. This Letter not only extends the application area of optical superlattices, but also offers an efficient method for wave-front shaping technology.

  1. Fabrication of 2D and 3D dendritic nanoarchitectures of CdS

    Institute of Scientific and Technical Information of China (English)

    GU Li

    2008-01-01

    The controlled preparation of two-dimensional (2D) and three-dimensional (3D) dendritic nanostructures of CdS was reported. 2D dendritic patterns are obtained through the self-assembly of nanoparticles under the entropy-driven force. 3D dendritic needle-like nanocrystals are prepared through an aqueous solution synthesis regulated by oleic acid molecules. Their growth mechanism is presumed to be the selective binding of OA molecules onto growing crystal planes. Techniques such as SEM, TEM, XRD, and FT-IR were employed to characterize the morphologies and structures of the obtained products.

  2. Optimization and practical implementation of ultrafast 2D NMR experiments

    OpenAIRE

    Queiroz Júnior,Luiz H. K.; Antonio G. Ferreira; Patrick Giraudeau

    2013-01-01

    Ultrafast 2D NMR is a powerful methodology that allows recording of a 2D NMR spectrum in a fraction of second. However, due to the numerous non-conventional parameters involved in this methodology its implementation is no trivial task. Here, an optimized experimental protocol is carefully described to ensure efficient implementation of ultrafast NMR. The ultrafast spectra resulting from this implementation are presented based on the example of two widely used 2D NMR experiments, COSY and HSQC...

  3. Stream flow recession patterns can help unravel the role of climate and humans in landscape co-evolution

    Directory of Open Access Journals (Sweden)

    P. W. Bogaart

    2015-09-01

    Brutsaert and Nieber (1977 analysis method to characterize streamflow recession behaviour of ≈ 200 Swedish catchments within the context of global change and landscape co-evolution. Results suggest that the Brutsaert–Nieber parameters are strongly linked to the climate, soil, land-use and their interdependencies. Many catchments show a trend towards more non-linear behaviour, meaning faster initial recession, but also slower recession towards baseflow. This trend has been found to be independent from climate change. Instead, we suggest that land cover change, both natural (restoration of natural soil profiles in forested areas and anthropogenic (reforestation and optimized water management, is probably responsible. Both change types are characterised by system adaptation and change, towards more optimal ecohydrological conditions, suggesting landscape co-evolution is at play. Given the observed magnitudes of recession changes during the past 50 years, predictions of future river discharge critically need to include effects of landscape co-evolution. The interconnections between the controls of land cover and climate on river recession behaviour, as we have quantified in this paper, provide first-order handles to do so.

  4. Age, distance, and geochemical evolution within a monogenetic volcanic field: Analyzing patterns in the Auckland Volcanic Field eruption sequence

    Science.gov (United States)

    Corvec, Nicolas Le; Bebbington, Mark S.; Lindsay, Jan M.; McGee, Lucy E.

    2013-09-01

    The Auckland Volcanic Field (AVF) is a young active monogenetic basaltic field, which contains ˜50 volcanoes scattered across the Auckland metropolitan area. Understanding the temporal, spatial, and chemical evolution of the AVF during the last c.a. 250 ka is crucial in order to forecast a future eruption. Recent studies have provided new age constraints and potential temporal sequences of the past eruptions within the AVF. We use this information to study how the spatial distribution of the volcanic centers evolves with time, and how the chemical composition of the erupted magmas evolves with time and space. We seek to develop a methodology which compares successive eruptions to describe the link between geochemical and spatiotemporal evolution of volcanic centers within a monogenetic volcanic field. This methodology is tested with the present day data of the AVF. The Poisson nearest neighbor analysis shows that the spatial behavior of the field has been constant overtime, with the spatial distribution of the volcanic centers fitting the Poisson model within the significance levels. The results of the meta-analysis show the existence of correlations between the chemical composition of the erupted magmas and distance, volume, and time. The apparent randomness of the spatiotemporal evolution of the volcanic centers observed at the surface is probably influenced by the activity of the source. The methodology developed in this study can be used to identify possible relationships between composition trends and volume, time and/or distance to the behavior of the source, for successive eruptions of the AVF.

  5. Topological Toughening of graphene and other 2D materials

    Science.gov (United States)

    Gao, Huajian

    It has been claimed that graphene, with the elastic modulus of 1TPa and theoretical strength as high as 130 GPa, is the strongest material. However, from an engineering point of view, it is the fracture toughness that determines the actual strength of materials, as crack-like flaws (i.e., cracks, holes, notches, corners, etc.) are inevitable in the design, fabrication, and operation of practical devices and systems. Recently, it has been demonstrated that graphene has very low fracture toughness, in fact close to that of ideally brittle solids. These findings have raised sharp questions and are calling for efforts to explore effective methods to toughen graphene. Recently, we have been exploring the potential use of topological effects to enhance the fracture toughness of graphene. For example, it has been shown that a sinusoidal graphene containing periodically distributed disclination quadrupoles can achieve a mode I fracture toughness nearly twice that of pristine graphene. Here we report working progresses on further studies of topological toughening of graphene and other 2D materials. A phase field crystal method is adopted to generate the atomic coordinates of material with specific topological patterns. We then perform molecular dynamics simulations of fracture in the designed samples, and observe a variety of toughening mechanisms, including crack tip blunting, crack trapping, ligament bridging, crack deflection and daughter crack initiation and coalescence.

  6. CYP2D6 polymorphism in relation to tramadol metabolism

    DEFF Research Database (Denmark)

    Halling, Jónrit; Weihe, Pál; Brosen, Kim

    2008-01-01

    to investigate whether the previously observed frequency of CYP2D6 poor metabolizers (PMs) in the Faroese, which was shown to be double that of other Europeans, was evident in a patient group medicated with a CYP2D6 substrate. The patients were CYP2D6-phenotyped by the intake of sparteine, followed by urine...... European populations (7%-10%). The concentrations of (+)-M1 when corrected for dose (nM/mg) and the (+)-M1/(+)-tramadol ratio were approximately 14-fold higher in the extensive metabolizers (EMs) than in the PMs. In conclusion, the impact of the CYP2D6 polymorphism on the pharmacokinetics of tramadol...

  7. Sparse Non-negative Matrix Factor 2-D Deconvolution

    DEFF Research Database (Denmark)

    Mørup, Morten; Schmidt, Mikkel N.

    2006-01-01

    We introduce the non-negative matrix factor 2-D deconvolution (NMF2D) model, which decomposes a matrix into a 2-dimensional convolution of two factor matrices. This model is an extension of the non-negative matrix factor deconvolution (NMFD) recently introduced by Smaragdis (2004). We derive...... and prove the convergence of two algorithms for NMF2D based on minimizing the squared error and the Kullback-Leibler divergence respectively. Next, we introduce a sparse non-negative matrix factor 2-D deconvolution model that gives easy interpretable decompositions and devise two algorithms for computing...

  8. Self-leveling 2D DPN probe arrays

    Science.gov (United States)

    Haaheim, Jason R.; Val, Vadim; Solheim, Ed; Bussan, John; Fragala, J.; Nelson, Mike

    2010-02-01

    Dip Pen Nanolithography® (DPN®) is a direct write scanning probe-based technique which operates under ambient conditions, making it suitable to deposit a wide range of biological and inorganic materials. Precision nanoscale deposition is a fundamental requirement to advance nanoscale technology in commercial applications, and tailoring chemical composition and surface structure on the sub-100 nm scale benefits researchers in areas ranging from cell adhesion to cell-signaling and biomimetic membranes. These capabilities naturally suggest a "Desktop Nanofab" concept - a turnkey system that allows a non-expert user to rapidly create high resolution, scalable nanostructures drawing upon well-characterized ink and substrate pairings. In turn, this system is fundamentally supported by a portfolio of MEMS devices tailored for microfluidic ink delivery, directed placement of nanoscale materials, and cm2 tip arrays for high-throughput nanofabrication. Massively parallel two-dimensional nanopatterning is now commercially available via NanoInk's 2D nano PrintArray™, making DPN a high-throughput (>3×107 μm2 per hour), flexible and versatile method for precision nanoscale pattern formation. However, cm2 arrays of nanoscopic tips introduce the nontrivial problem of getting them all evenly touching the surface to ensure homogeneous deposition; this requires extremely precise leveling of the array. Herein, we describe how we have made the process simple by way of a selfleveling gimbal attachment, coupled with semi-automated software leveling routines which bring the cm^2 chip to within 0.002 degrees of co-planarity. This excellent co-planarity yields highly homogeneous features across a square centimeter, with standard deviation. We have engineered the devices to be easy to use, wire-free, and fully integrated with both of our patterning tools: the DPN 5000, and the NLP 2000.

  9. Comprehensive analysis of long non-coding RNAs highlights their spatio-temporal expression patterns and evolutional conservation in Sus scrofa

    Science.gov (United States)

    Tang, Zhonglin; Wu, Yang; Yang, Yalan; Yang, Yu-Cheng T.; Wang, Zishuai; Yuan, Jiapei; Yang, Yang; Hua, Chaoju; Fan, Xinhao; Niu, Guanglin; Zhang, Yubo; Lu, Zhi John; Li, Kui

    2017-01-01

    Despite modest sequence conservation and rapid evolution, long non-coding RNAs (lncRNAs) appear to be conserved in expression pattern and function. However, analysis of lncRNAs across tissues and developmental stages remains largely uncharacterized in mammals. Here, we systematically investigated the lncRNAs of the Guizhou miniature pig (Sus scrofa), which was widely used as biomedical model. We performed RNA sequencing across 9 organs and 3 developmental skeletal muscle, and developed a filtering pipeline to identify 10,813 lncRNAs (9,075 novel). Conservation patterns analysis revealed that 57% of pig lncRNAs showed homology to humans and mice based on genome alignment. 5,455 lncRNAs exhibited typical hallmarks of regulatory molecules, such as high spatio-temporal specificity. Notably, conserved lncRNAs exhibited higher tissue specificity than pig-specific lncRNAs and were significantly enriched in testis and ovary. Weighted co-expression network analysis revealed a set of conserved lncRNAs that are likely involved in postnatal muscle development. Based on the high degree of similarity in the structure, organization, and dynamic expression of pig lncRNAs compared with human and mouse lncRNAs, we propose that these lncRNAs play an important role in organ physiology and development in mammals. Our results provide a resource for studying animal evolution, morphological complexity, breeding, and biomedical research. PMID:28233874

  10. Comprehensive analysis of long non-coding RNAs highlights their spatio-temporal expression patterns and evolutional conservation in Sus scrofa.

    Science.gov (United States)

    Tang, Zhonglin; Wu, Yang; Yang, Yalan; Yang, Yu-Cheng T; Wang, Zishuai; Yuan, Jiapei; Yang, Yang; Hua, Chaoju; Fan, Xinhao; Niu, Guanglin; Zhang, Yubo; Lu, Zhi John; Li, Kui

    2017-02-24

    Despite modest sequence conservation and rapid evolution, long non-coding RNAs (lncRNAs) appear to be conserved in expression pattern and function. However, analysis of lncRNAs across tissues and developmental stages remains largely uncharacterized in mammals. Here, we systematically investigated the lncRNAs of the Guizhou miniature pig (Sus scrofa), which was widely used as biomedical model. We performed RNA sequencing across 9 organs and 3 developmental skeletal muscle, and developed a filtering pipeline to identify 10,813 lncRNAs (9,075 novel). Conservation patterns analysis revealed that 57% of pig lncRNAs showed homology to humans and mice based on genome alignment. 5,455 lncRNAs exhibited typical hallmarks of regulatory molecules, such as high spatio-temporal specificity. Notably, conserved lncRNAs exhibited higher tissue specificity than pig-specific lncRNAs and were significantly enriched in testis and ovary. Weighted co-expression network analysis revealed a set of conserved lncRNAs that are likely involved in postnatal muscle development. Based on the high degree of similarity in the structure, organization, and dynamic expression of pig lncRNAs compared with human and mouse lncRNAs, we propose that these lncRNAs play an important role in organ physiology and development in mammals. Our results provide a resource for studying animal evolution, morphological complexity, breeding, and biomedical research.

  11. Decoupled Estimation of 2D DOA for Coherently Distributed Sources Using 3D Matrix Pencil Method

    Directory of Open Access Journals (Sweden)

    Tang Bin

    2008-08-01

    Full Text Available A new 2D DOA estimation method for coherently distributed (CD source is proposed. CD sources model is constructed by using Taylor approximation to the generalized steering vector (GSV, whereas the angular and angular spread are separated from signal pattern. The angular information is in the phase part of the GSV, and the angular spread information is in the module part of the GSV, thus enabling to decouple the estimation of 2D DOA from that of the angular spread. The array received data is used to construct three-dimensional (3D enhanced data matrix. The 2D DOA for coherently distributed sources could be estimated from the enhanced matrix by using 3D matrix pencil method. Computer simulation validated the efficiency of the algorithm.

  12. Fabrication and magnetic behaviour of 2D ordered Fe/SiO2 nanodots array

    Science.gov (United States)

    Liu, W.; Zhong, W.; Qiu, L. J.; Lü, L. Y.; Du, Y. W.

    2006-06-01

    We have demonstrated a simple and universal morphology-controlled growth of 2D ordered Fe/SiO2 magnetic nanodots array, which was based on 2D colloidal monolayer template composed of polystyrene (PS) spheres and one-step sol-gel spin-coating technique. The Fe/SiO2 nanodots have a well-ordered structure arranged in a hexagonal pattern. The dots have the shape of quasi-pyramidal tetrahedron, which reside in the interstitial region between three PS spheres and the substrate. Magnetic measurements reveal that the nanodots array exhibits the in-plane easy magnetization direction. Compared with the unpatterned Fe/SiO2 thin film, the dots array has lower saturated field, higher remanence and coercivity. The present method is applicable to 2D ordered nanodots array of other magnetic materials.

  13. Follicular lymphoma (in situ) pattern in the bone marrow: does it indicate an early stage in disease evolution?

    Science.gov (United States)

    Alobeid, Bachir; Mears, John Gregory; Bhagat, Govind

    2015-01-01

    Key Clinical Message Bone marrow involvement by an isolated interstitial lymphoid aggregate exhibiting the pattern and phenotype described for follicular lymphoma in situ (FLIS) has not been reported before. The detection of clinically silent FL in this case highlights the necessity of complete staging workup when such lesions are encountered in biopsies. PMID:26185645

  14. Graph-Based Transform for 2D Piecewise Smooth Signals With Random Discontinuity Locations.

    Science.gov (United States)

    Zhang, Dong; Liang, Jie

    2017-04-01

    The graph-based block transform recently emerged as an effective tool for compressing some special signals such as depth images in 3D videos. However, in existing methods, overheads are required to describe the graph of the block, from which the decoder has to calculate the transform via time-consuming eigendecomposition. To address these problems, in this paper, we aim to develop a single graph-based transform for a class of 2D piecewise smooth signals with similar discontinuity patterns. We first consider the deterministic case with a known discontinuity location in each row. We propose a 2D first-order autoregression (2D AR1) model and a 2D graph for this type of signals. We show that the closed-form expression of the inverse of a biased Laplacian matrix of the proposed 2D graph is exactly the covariance matrix of the proposed 2D AR1 model. Therefore, the optimal transform for the signal are the eigenvectors of the proposed graph Laplacian. Next, we show that similar results hold in the random case, where the locations of the discontinuities in different rows are randomly distributed within a confined region, and we derive the closed-form expression of the corresponding optimal 2D graph Laplacian. The theory developed in this paper can be used to design both pre-computed transforms and signal-dependent transforms with low complexities. Finally, depth image coding experiments demonstrate that our methods can achieve similar performance to the state-of-the-art method, but our complexity is much lower.

  15. An Incompressible 2D Didactic Model with Singularity and Explicit Solutions of the 2D Boussinesq Equations

    Science.gov (United States)

    Chae, Dongho; Constantin, Peter; Wu, Jiahong

    2014-09-01

    We give an example of a well posed, finite energy, 2D incompressible active scalar equation with the same scaling as the surface quasi-geostrophic equation and prove that it can produce finite time singularities. In spite of its simplicity, this seems to be the first such example. Further, we construct explicit solutions of the 2D Boussinesq equations whose gradients grow exponentially in time for all time. In addition, we introduce a variant of the 2D Boussinesq equations which is perhaps a more faithful companion of the 3D axisymmetric Euler equations than the usual 2D Boussinesq equations.

  16. The evolution pattern of rDNA ITS in Avena and phylogenetic relationship of the Avena species (Poaceae: Aveneae).

    Science.gov (United States)

    Peng, Yuan-Ying; Baum, Bernard R; Ren, Chang-Zhong; Jiang, Qian-Tao; Chen, Guo-Yue; Zheng, You-Liang; Wei, Yu-Ming

    2010-10-01

    Ribosomal ITS sequences are commonly used for phylogenetic reconstruction because they are included in rDNA repeats, and these repeats often undergo rapid concerted evolution within and between arrays. Therefore, the rDNA ITS copies appear to be virtually identical and can sometimes be treated as a single gene. In this paper we examined ITS polymorphism within and among 13 diploid (A and C genomes), seven tetraploid (AB, AC and CC genomes) and four hexaploid (ACD genome) to infer the extent and direction of concerted evolution, and to reveal the phylogenetic and genome relationship among species of Avena. A total of 170 clones of the ITS1-5.8S-ITS2 fragment were sequenced to carry out haplotype and phylogenetic analysis. In addition, 111 Avena ITS sequences retrieved from GenBank were combined with 170 clones to construct a phylogeny and a network. We demonstrate the major divergence between the A and C genomes whereas the distinction among the A and B/D genomes was generally not possible. High affinity among the A(d) genome species A. damascena and the ACD genome species A. fatua was found, whereas the rest of the ACD genome hexaploids and the AACC tetraploids were highly affiliated with the A(l) genome diploid A. longiglumis. One of the AACC species A. murphyi showed the closest relationship with most of the hexaploid species. Both C(v) and C(p) genome species have been proposed as paternal donors of the C-genome carrying polyploids. Incomplete concerted evolution is responsible for the observed differences among different clones of a single Avena individual. The elimination of C-genome rRNA sequences and the resulting evolutionary inference of hexaploid species are discussed.

  17. Dissociation of expression patterns of homeodomain transcription factors in the evolution of developmental mode in the sea urchins Heliocidaris tuberculata and H. erythrogramma.

    Science.gov (United States)

    Wilson, Keen A; Andrews, Mary E; Raff, Rudolf A

    2005-01-01

    The direct-developing sea urchin species Heliocidaris erythrogramma has a radically modified ontogeny. Along with gains of novel features, its entire ectoderm has been reorganized, resulting in the apparent absence of a differentiated oral ectoderm, a major module present in the pluteus of indirect-developing species, such as H. tuberculata. The restoration of an obvious oral ectoderm in H. erythrogrammaxH. tuberculata hybrids, indicates the action of dominant regulatory factors from the H. tuberculata genome. We sought candidate regulatory genes based on the prediction that they should include genes that govern development of the oral ectoderm in the pluteus, but play different roles in H. erythrogramma. Such genes may have a large effect in the evolution of development. Goosecoid (Gsc), Msx, and the sea urchin Abd-B-like gene (Hox11/13b) are present and expressed in both species and the hybrid embryos. Both Gsc and Msx are oral ectoderm specific in H. tuberculata, and show novel and distinct expression patterns in H. erythrogramma. Gsc assumes a novel ectodermal pattern and Msx shifts to a novel and largely mesodermal pattern. Both Gsc and Msx show a restoration of oral ectoderm expression in hybrids. Hox11/13b is not expressed in oral ectoderm in H. tuberculata, but is conserved in posterior spatial expression among H. tuberculata, H. erythrogramma and hybrids, serving as a control. Competitive RT-PCR shows that Gsc, Msx, and Hox11/13b are under different quantitative and temporal controls in the Heliocidaris species and the hybrids. The implications for the involvement of these genes in the rapid evolution of a direct developing larva are discussed.

  18. Acute myocarditis with normal wall motion detected with 2D speckle tracking echocardiography

    Directory of Open Access Journals (Sweden)

    Thomas Sturmberger

    2016-05-01

    Full Text Available We present the case of a 26-year-old male with acute tonsillitis who was referred for coronary angiography because of chest pain, elevated cardiac biomarkers, and biphasic T waves. The patient had no cardiovascular risk factors. Echocardiography showed no wall motion abnormalities and no pericardial effusion. 2D speckle tracking revealed distinct decreased regional peak longitudinal systolic strain in the lateral and posterior walls. Ischemic disease was extremely unlikely in view of his young age, negative family history regarding coronary artery disease, and lack of regional wall motion abnormalities on the conventional 2D echocardiogram. Coronary angiography was deferred as myocarditis was suspected. To confirm the diagnosis, cardiac magnetic resonance tomography (MRT was performed, showing subepicardial delayed hyperenhancement in the lateral and posterior walls correlating closely with the strain pattern obtained by 2D speckle tracking echocardiography. With a working diagnosis of acute myocarditis associated with acute tonsillitis, we prescribed antibiotics and nonsteroidal anti-inflammatory drugs. The patient’s clinical signs resolved along with normalization of serum creatine kinase (CK levels, and the patient was discharged on the third day after admission. Learning points: • Acute myocarditis can mimic acute coronary syndromes. • Conventional 2D echocardiography lacks specific features for detection of subtle regional wall motion abnormalities. • 2D speckle tracking expands the scope of echocardiography in identifying myocardial dysfunction derived from edema in acute myocarditis.

  19. Distinctive expression patterns of Hedgehog pathway genes in the Ciona intestinalis larva: implications for a role of Hedgehog signaling in postembryonic development and chordate evolution.

    Science.gov (United States)

    Islam, A F M Tariqul; Moly, Pricila Khan; Miyamoto, Yuki; Kusakabe, Takehiro G

    2010-02-01

    Members of the Hedgehog (Hh) family are soluble ligands that orchestrate a wide spectrum of developmental processes ranging from left-right axis determination of the embryo to tissue patterning and organogenesis. Tunicates, including ascidians, are the closest relatives of vertebrates, and elucidation of Hh signaling in ascidians should provide an important clue towards better understanding the role of this pathway in development. In previous studies, expression patterns of genes encoding Hh and its downstream factor Gli have been examined up to the tailbud stage in the ascidian embryo, but their expression in the larva has not been reported. Here we show the spatial expression patterns of hedgehog (Ci-hh1, Ci-hh2), patched (Ci-ptc), smoothened (Ci-smo), and Gli (Ci-Gli) orthologs in larvae of the ascidian Ciona intestinalis. The expression patterns of Ci-hh2 and Ci-Gli dramatically change during the period between the late tailbud embryo and the swimming larva. At the larval stage, expression of Ci-Gli was found in a central part of the endoderm and in the visceral ganglion, while Ci-hh2 was expressed in two discrete endodermal regions, anteriorly and posteriorly adjacent to the cells expressing Gli. The expression patterns of these genes suggest that the Hh ligand controls postembryonic development of the endoderm and the central nervous system. Expression of a gene encoding Hh in the anterior and/or pharyngeal endoderm is probably an ancient chordate character; diversification of regulation and targets of the Hh signaling in this region may have played a major role in the evolution of chordate body structures.

  20. Energy Efficiency of D2D Multi-User Cooperation.

    Science.gov (United States)

    Zhang, Zufan; Wang, Lu; Zhang, Jie

    2017-03-28

    The Device-to-Device (D2D) communication system is an important part of heterogeneous networks. It has great potential to improve spectrum efficiency, throughput and energy efficiency cooperation of multiple D2D users with the advantage of direct communication. When cooperating, D2D users expend extraordinary energy to relay data to other D2D users. Hence, the remaining energy of D2D users determines the life of the system. This paper proposes a cooperation scheme for multiple D2D users who reuse the orthogonal spectrum and are interested in the same data by aiming to solve the energy problem of D2D users. Considering both energy availability and the Signal to Noise Ratio (SNR) of each D2D user, the Kuhn-Munkres algorithm is introduced in the cooperation scheme to solve relay selection problems. Thus, the cooperation issue is transformed into a maximum weighted matching (MWM) problem. In order to enhance energy efficiency without the deterioration of Quality of Service (QoS), the link outage probability is derived according to the Shannon Equation by considering the data rate and delay. The simulation studies the relationships among the number of cooperative users, the length of shared data, the number of data packets and energy efficiency.

  1. Cascading Constrained 2-D Arrays using Periodic Merging Arrays

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Laursen, Torben Vaarby

    2003-01-01

    We consider a method for designing 2-D constrained codes by cascading finite width arrays using predefined finite width periodic merging arrays. This provides a constructive lower bound on the capacity of the 2-D constrained code. Examples include symmetric RLL and density constrained codes....... Numerical results for the capacities are presented....

  2. Animación 2D: curriculum vitae animado

    OpenAIRE

    CANTOS BELMONTE, CONSUELO

    2015-01-01

    Trabajo Fin de Grado de animación 2D donde un personaje (alter ego de la animadora) expone, mediante la interación con una Voz en Off y su sombra, el curriclum vitae de la animadora. Cantos Belmonte, C. (2014). Animación 2D: curriculum vitae animado. http://hdl.handle.net/10251/45910. Archivo delegado

  3. Symmetries and solvable models for evaporating 2D black holes

    CERN Document Server

    Cruz, J; Navarro-Salas, J; Talavera, C F

    1997-01-01

    We study the evaporation process of a 2D black hole in thermal equilibrium when the ingoing radiation is switched off suddenly. We also introduce global symmetries of generic 2D dilaton gravity models which generalize the extra symmetry of the CGHS model.

  4. New Type of 2-D Laser Doppler Vibrometer

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The fundamentals and method of 2-D laser Doppler vibrometer are introduced.The factors influencing the measuring accuracy are analyzed. Moreover, the circuit for signal processing is designed. The vibrating amplitude and frequency of 2-D vibration in wider range can be measured simultaneously in non-contact means,the measuring results are accurate.

  5. The relation between Euclidean and Lorentzian 2D quantum gravity

    NARCIS (Netherlands)

    Ambjørn, J.; Correia, J.; Kristjansen, C.; Loll, R.

    2006-01-01

    Starting from 2D Euclidean quantum gravity, we show that one recovers 2D Lorentzian quantum gravity by removing all baby universes. Using a peeling procedure to decompose the discrete, triangulated geometries along a one-dimensional path, we explicitly associate with each Euclidean space-time a (gen

  6. Sensitivity of 2-D complex resistivity measurements to subsurface anisotropy

    Science.gov (United States)

    Kenkel, J.; Kemna, A.

    2017-02-01

    In general, the complex electrical resistivity in the subsurface is anisotropic. Despite this, algorithms for the tomographic inversion of complex resistivity data commonly assume isotropy, mainly due to the lack of anisotropic modelling and inversion schemes, potentially leading to artefacts in the inversion results in the presence of anisotropy. The development of an effective anisotropic complex resistivity inversion algorithm which utilizes the gradient information of some cost function benefits from understanding the characteristics of the problem's sensitivities, that is, the partial derivative of the impedance forward response with respect to the complex conductivities in the different spatial directions, as well as with respect to the different ratios of complex conductivities, that is, the different anisotropy ratios. We here derive expressions for these sensitivities and, based on a 2.5-D finite-element modelling algorithm, we compute and discuss sensitivity distributions as well as measurement response curves of typical surface and cross-borehole measurement configurations for 2-D subsurface anisotropic complex resistivity distributions. Depending on the electrode layout and measurement configuration, the sensitivity with respect to the conductivity in a particular direction shows a unique pattern, while for other directions sensitivity patterns are qualitatively similar. These sensitivity characteristics translate into important equivalences between impedance responses of local anisotropic and isotropic anomalies, for both magnitude and phase. Accordingly, with collinear surface arrays only the complex conductivity in the direction of the electrode layout can be unambiguously resolved, and with cross-borehole arrays only the conductivity in the vertical direction, provided an in-hole current injection is used. Nevertheless, anisotropy ratios involving these resolvable conductivity components are likewise detectable. The distinct shape of the measurement

  7. 2D materials and van der Waals heterostructures.

    Science.gov (United States)

    Novoselov, K S; Mishchenko, A; Carvalho, A; Castro Neto, A H

    2016-07-29

    The physics of two-dimensional (2D) materials and heterostructures based on such crystals has been developing extremely fast. With these new materials, truly 2D physics has begun to appear (for instance, the absence of long-range order, 2D excitons, commensurate-incommensurate transition, etc.). Novel heterostructure devices--such as tunneling transistors, resonant tunneling diodes, and light-emitting diodes--are also starting to emerge. Composed from individual 2D crystals, such devices use the properties of those materials to create functionalities that are not accessible in other heterostructures. Here we review the properties of novel 2D crystals and examine how their properties are used in new heterostructure devices.

  8. Evolution of seismic signals and slip patterns along subduction zones: insights from a friction lab scale experiment

    CERN Document Server

    Voisin, Christophe; Larose, Eric; Renard, François

    2008-01-01

    Continuous GPS and broadband seismic monitoring have revealed a variety of disparate slip patterns especially in shallow dipping subduction zones, among which regular earthquakes, slow slip events and silent quakes1,2. Slow slip events are sometimes accompanied by Non Volcanic Tremors (NVT), which origin remains unclear3, either related to fluid migration or to friction. The present understanding of the whole menagerie of slip patterns is based upon numerical simulations imposing ad hoc values of the rate and state parameters a and b4-6 derived from the temperature dependence of a and b of a wet granite gouge7. Here we investigate the influence of the cumulative slip on the frictional and acoustic patterns of a lab scale subduction zone. Shallow loud earthquakes (stick-slip events), medium depth slow, deeper silent quakes (smooth sliding oscillations) and deepest steady-state creep (continuous sliding) are reproduced by the ageing of contact interface with cumulative displacement8. The Acoustic Emission evolv...

  9. Sub-wavelength Lithography of Complex 2D and 3D Nanostructures without Dyes

    CERN Document Server

    Chaudhary, Raghvendra P; Ummethala, Govind; Hawal, Suyog R; Saxena, Sumit; Shukla, Shobha

    2016-01-01

    One-photon or two photon absorption by dye molecules in photopolymers enable direct 2D & 3D lithography of micro/nano structures with high spatial resolution and can be used effectively in fabricating artificially structured nanomaterials. However, the major bottleneck in unleashing the potential of this useful technique is the indispensable usage of dyes that are extremely expensive, highly toxic and usually insoluble in commercially available photopolymers. Here we report a simple, inexpensive and one-step technique for direct-writing of micro/nanostructures, with sub-wavelength resolution at extremely high speeds without using any one photon or two photon absorbing dye. We incorporated large amount (20 weight %) of inexpensive photoinitiator into the photopolymer and utilized its two-photon absorbing property for sub-wavelength patterning. Complex 2D and 3D patterns were fabricated with sub-micron resolution, in commercially available liquid photopolymer to show the impact/versatility of this technique...

  10. Low band gap frequencies and multiplexing properties in 1D and 2D mass spring structures

    Science.gov (United States)

    Aly, Arafa H.; Mehaney, Ahmed

    2016-11-01

    This study reports on the propagation of elastic waves in 1D and 2D mass spring structures. An analytical and computation model is presented for the 1D and 2D mass spring systems with different examples. An enhancement in the band gap values was obtained by modeling the structures to obtain low frequency band gaps at small dimensions. Additionally, the evolution of the band gap as a function of mass value is discussed. Special attention is devoted to the local resonance property in frequency ranges within the gaps in the band structure for the corresponding infinite periodic lattice in the 1D and 2D mass spring system. A linear defect formed of a row of specific masses produces an elastic waveguide that transmits at the narrow pass band frequency. The frequency of the waveguides can be selected by adjusting the mass and stiffness coefficients of the materials constituting the waveguide. Moreover, we pay more attention to analyze the wave multiplexer and DE-multiplexer in the 2D mass spring system. We show that two of these tunable waveguides with alternating materials can be employed to filter and separate specific frequencies from a broad band input signal. The presented simulation data is validated through comparison with the published research, and can be extended in the development of resonators and MEMS verification.

  11. A new approach to river bank retreat and advance in 2D numerical models of fluvial morphodynamics

    NARCIS (Netherlands)

    Spruyt, A.; Mosselman, E.; Jagers, B.

    2011-01-01

    River bank retreat and advance are modes of morphological evolution in addition to bed level changes and changes in bed sediment composition. They produce planform changes such as width adjustment and meander bend migration. However, their reproduction in a 2D numerical model still remains a challen

  12. 2D vs. 3D mammography observer study

    Science.gov (United States)

    Fernandez, James Reza F.; Hovanessian-Larsen, Linda; Liu, Brent

    2011-03-01

    Breast cancer is the most common type of non-skin cancer in women. 2D mammography is a screening tool to aid in the early detection of breast cancer, but has diagnostic limitations of overlapping tissues, especially in dense breasts. 3D mammography has the potential to improve detection outcomes by increasing specificity, and a new 3D screening tool with a 3D display for mammography aims to improve performance and efficiency as compared to 2D mammography. An observer study using a mammography phantom was performed to compare traditional 2D mammography with this ne 3D mammography technique. In comparing 3D and 2D mammography there was no difference in calcification detection, and mass detection was better in 2D as compared to 3D. There was a significant decrease in reading time for masses, calcifications, and normals in 3D compared to 2D, however, as well as more favorable confidence levels in reading normal cases. Given the limitations of the mammography phantom used, however, a clearer picture in comparing 3D and 2D mammography may be better acquired with the incorporation of human studies in the future.

  13. An automated pipeline to screen membrane protein 2D crystallization.

    Science.gov (United States)

    Kim, Changki; Vink, Martin; Hu, Minghui; Love, James; Stokes, David L; Ubarretxena-Belandia, Iban

    2010-06-01

    Electron crystallography relies on electron cryomicroscopy of two-dimensional (2D) crystals and is particularly well suited for studying the structure of membrane proteins in their native lipid bilayer environment. To obtain 2D crystals from purified membrane proteins, the detergent in a protein-lipid-detergent ternary mixture must be removed, generally by dialysis, under conditions favoring reconstitution into proteoliposomes and formation of well-ordered lattices. To identify these conditions a wide range of parameters such as pH, lipid composition, lipid-to-protein ratio, ionic strength and ligands must be screened in a procedure involving four steps: crystallization, specimen preparation for electron microscopy, image acquisition, and evaluation. Traditionally, these steps have been carried out manually and, as a result, the scope of 2D crystallization trials has been limited. We have therefore developed an automated pipeline to screen the formation of 2D crystals. We employed a 96-well dialysis block for reconstitution of the target protein over a wide range of conditions designed to promote crystallization. A 96-position magnetic platform and a liquid handling robot were used to prepare negatively stained specimens in parallel. Robotic grid insertion into the electron microscope and computerized image acquisition ensures rapid evaluation of the crystallization screen. To date, 38 2D crystallization screens have been conducted for 15 different membrane proteins, totaling over 3000 individual crystallization experiments. Three of these proteins have yielded diffracting 2D crystals. Our automated pipeline outperforms traditional 2D crystallization methods in terms of throughput and reproducibility.

  14. Evolution of Xylan Substitution Patterns in Gymnosperms and Angiosperms: Implications for Xylan Interaction with Cellulose1[OPEN

    Science.gov (United States)

    Li, An; Gomes, Thiago C.F.

    2016-01-01

    The interaction between cellulose and xylan is important for the load-bearing secondary cell wall of flowering plants. Based on the precise, evenly spaced pattern of acetyl and glucuronosyl (MeGlcA) xylan substitutions in eudicots, we recently proposed that an unsubstituted face of xylan in a 2-fold helical screw can hydrogen bond to the hydrophilic surfaces of cellulose microfibrils. In gymnosperm cell walls, any role for xylan is unclear, and glucomannan is thought to be the important cellulose-binding polysaccharide. Here, we analyzed xylan from the secondary cell walls of the four gymnosperm lineages (Conifer, Gingko, Cycad, and Gnetophyta). Conifer, Gingko, and Cycad xylan lacks acetylation but is modified by arabinose and MeGlcA. Interestingly, the arabinosyl substitutions are located two xylosyl residues from MeGlcA, which is itself placed precisely on every sixth xylosyl residue. Notably, the Gnetophyta xylan is more akin to early-branching angiosperms and eudicot xylan, lacking arabinose but possessing acetylation on alternate xylosyl residues. All these precise substitution patterns are compatible with gymnosperm xylan binding to hydrophilic surfaces of cellulose. Molecular dynamics simulations support the stable binding of 2-fold screw conifer xylan to the hydrophilic face of cellulose microfibrils. Moreover, the binding of multiple xylan chains to adjacent planes of the cellulose fibril stabilizes the interaction further. Our results show that the type of xylan substitution varies, but an even pattern of xylan substitution is maintained among vascular plants. This suggests that 2-fold screw xylan binds hydrophilic faces of cellulose in eudicots, early-branching angiosperm, and gymnosperm cell walls. PMID:27325663

  15. 2-D Versus 3-D Magnetotelluric Data Interpretation

    Science.gov (United States)

    Ledo, Juanjo

    2005-09-01

    In recent years, the number of publications dealing with the mathematical and physical 3-D aspects of the magnetotelluric method has increased drastically. However, field experiments on a grid are often impractical and surveys are frequently restricted to single or widely separated profiles. So, in many cases we find ourselves with the following question: is the applicability of the 2-D hypothesis valid to extract geoelectric and geological information from real 3-D environments? The aim of this paper is to explore a few instructive but general situations to understand the basics of a 2-D interpretation of 3-D magnetotelluric data and to determine which data subset (TE-mode or TM-mode) is best for obtaining the electrical conductivity distribution of the subsurface using 2-D techniques. A review of the mathematical and physical fundamentals of the electromagnetic fields generated by a simple 3-D structure allows us to prioritise the choice of modes in a 2-D interpretation of responses influenced by 3-D structures. This analysis is corroborated by numerical results from synthetic models and by real data acquired by other authors. One important result of this analysis is that the mode most unaffected by 3-D effects depends on the position of the 3-D structure with respect to the regional 2-D strike direction. When the 3-D body is normal to the regional strike, the TE-mode is affected mainly by galvanic effects, while the TM-mode is affected by galvanic and inductive effects. In this case, a 2-D interpretation of the TM-mode is prone to error. When the 3-D body is parallel to the regional 2-D strike the TE-mode is affected by galvanic and inductive effects and the TM-mode is affected mainly by galvanic effects, making it more suitable for 2-D interpretation. In general, a wise 2-D interpretation of 3-D magnetotelluric data can be a guide to a reasonable geological interpretation.

  16. Kalman Filter for Generalized 2-D Roesser Models

    Institute of Scientific and Technical Information of China (English)

    SHENG Mei; ZOU Yun

    2007-01-01

    The design problem of the state filter for the generalized stochastic 2-D Roesser models, which appears when both the state and measurement are simultaneously subjected to the interference from white noise, is discussed. The wellknown Kalman filter design is extended to the generalized 2-D Roesser models. Based on the method of "scanning line by line", the filtering problem of generalized 2-D Roesser models with mode-energy reconstruction is solved. The formula of the optimal filtering, which minimizes the variance of the estimation error of the state vectors, is derived. The validity of the designed filter is verified by the calculation steps and the examples are introduced.

  17. Harvest Survive : Game Mechanics of Unity 2D Game

    OpenAIRE

    2014-01-01

    The purpose of this project was to learn how to create Games in Unity 2D, to see the work-flow and to test if the new Unity 2D feature of the Unity engine was a good alternative for developing 2D games. A further aspect was to learn the different steps and mechanics of the Unity environment. The goal was to create a survival game, in which the player would have to grow plants in order to get food and money to stay alive in a hostile environment. The player has to survive in six different...

  18. Optimization and practical implementation of ultrafast 2D NMR experiments

    Energy Technology Data Exchange (ETDEWEB)

    Queiroz Junior, Luiz H. K., E-mail: professorkeng@gmail.com [Universidade Federal de Sao Carlos (UFSC), SP (Brazil). Departamento de Quimica; Universidade Federal de Goias (UFGO), Goiania, GO (Brazil). Inst. de Quimica; Ferreira, Antonio G. [Universidade Federal de Sao Carlos (UFSC), SP (Brazil). Departamento de Quimica; Giraudeau, Patrick [Universite de Nantes (France). CNRS, Chimie et Interdisciplinarite: Synthese, Analyse, Modelisation

    2013-09-01

    Ultrafast 2D NMR is a powerful methodology that allows recording of a 2D NMR spectrum in a fraction of second. However, due to the numerous non-conventional parameters involved in this methodology its implementation is no trivial task. Here, an optimized experimental protocol is carefully described to ensure efficient implementation of ultrafast NMR. The ultrafast spectra resulting from this implementation are presented based on the example of two widely used 2D NMR experiments, COSY and HSQC, obtained in 0.2 s and 41 s, respectively. (author)

  19. Spin Waves in 2D ferromagnetic square lattice stripe

    OpenAIRE

    Ahmed, Maher Z.

    2011-01-01

    In this work, the area and edges spin wave calculations were carried out using the Heisenberg Hamiltonian and the tridiagonal method for the 2D ferromagnetic square lattice stripe, where the SW modes are characterized by a 1D in-plane wave vector $q_x$. The results show a general and an unexpected feature that the area and edge spin waves only exist as optic modes. This behavior is also seen in 2D Heisenberg antiferromagnetic square lattice. This absence of the acoustic modes in the 2D square...

  20. Optimization and practical implementation of ultrafast 2D NMR experiments

    Directory of Open Access Journals (Sweden)

    Luiz H. K. Queiroz Júnior

    2013-01-01

    Full Text Available Ultrafast 2D NMR is a powerful methodology that allows recording of a 2D NMR spectrum in a fraction of second. However, due to the numerous non-conventional parameters involved in this methodology its implementation is no trivial task. Here, an optimized experimental protocol is carefully described to ensure efficient implementation of ultrafast NMR. The ultrafast spectra resulting from this implementation are presented based on the example of two widely used 2D NMR experiments, COSY and HSQC, obtained in 0.2 s and 41 s, respectively.

  1. Introduction to game physics with Box2D

    CERN Document Server

    Parberry, Ian

    2013-01-01

    Written by a pioneer of game development in academia, Introduction to Game Physics with Box2D covers the theory and practice of 2D game physics in a relaxed and entertaining yet instructional style. It offers a cohesive treatment of the topics and code involved in programming the physics for 2D video games. Focusing on writing elementary game physics code, the first half of the book helps you grasp the challenges of programming game physics from scratch, without libraries or outside help. It examines the mathematical foundation of game physics and illustrates how it is applied in practice thro

  2. 2D electron cyclotron emission imaging at ASDEX Upgrade (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Classen, I. G. J. [Max Planck Institut fuer Plasmaphysik, 85748 Garching (Germany); FOM-Institute for Plasma Physics, Rijnhuizen, 3430 BE Nieuwegein (Netherlands); Boom, J. E.; Vries, P. C. de [FOM-Institute for Plasma Physics, Rijnhuizen, 3430 BE Nieuwegein (Netherlands); Suttrop, W.; Schmid, E.; Garcia-Munoz, M.; Schneider, P. A. [Max Planck Institut fuer Plasmaphysik, 85748 Garching (Germany); Tobias, B.; Domier, C. W.; Luhmann, N. C. Jr. [University of California at Davis, Davis, California 95616 (United States); Donne, A. J. H. [FOM-Institute for Plasma Physics, Rijnhuizen, 3430 BE Nieuwegein (Netherlands); Eindhoven University of Technology, 5600 MB Eindhoven (Netherlands); Jaspers, R. J. E. [Eindhoven University of Technology, 5600 MB Eindhoven (Netherlands); Park, H. K. [POSTECH, Pohang, Gyeongbuk, 790-784 (Korea, Republic of); Munsat, T. [University of Colorado, Boulder, Colorado 80309 (United States)

    2010-10-15

    The newly installed electron cyclotron emission imaging diagnostic on ASDEX Upgrade provides measurements of the 2D electron temperature dynamics with high spatial and temporal resolution. An overview of the technical and experimental properties of the system is presented. These properties are illustrated by the measurements of the edge localized mode and the reversed shear Alfven eigenmode, showing both the advantage of having a two-dimensional (2D) measurement, as well as some of the limitations of electron cyclotron emission measurements. Furthermore, the application of singular value decomposition as a powerful tool for analyzing and filtering 2D data is presented.

  3. Phylogeography, Interaction Patterns and the Evolution of Host Choice in Drosophila-Parasitoid Systems in Ryukyu Archipelago and Taiwan.

    Directory of Open Access Journals (Sweden)

    Biljana Novković

    Full Text Available Island biotas provide a great opportunity to study not only the phylogeographic patterns of a group of species, but also to explore the differentiation in their coevolutionary interactions. Drosophila and their parasitoids are exemplary systems for studying complex interaction patterns. However, there is a lack of studies combining interaction-based and molecular marker-based methods. We applied an integrated approach combining phylogeography, interaction, and host-choice behavior studies, with the aim to understand how coevolutionary interactions evolve in Drosophila-parasitoid island populations. The study focused on the three most abundant Drosophila species in Ryukyu archipelago and Taiwan: D. albomicans, D. bipectinata, and D. takahashii, and the Drosophila-parasitoid Leptopilina ryukyuensis. We determined mitochondrial COI haplotypes for samples representing five island populations of Drosophila and four island populations of L. ryukyuensis. We additionally sequenced parts of the autosomal Gpdh for Drosophila samples, and the ITS2 for parasitoid samples. Phylogenetic and coalescent analyses were used to test for demographic events and to place them in a temporal framework. Geographical differences in Drosophila-parasitoid interactions were studied in host-acceptance, host-suitability, and host-choice experiments. All four species showed species-specific phylogeographic patterns. A general trend of the haplotype diversity increasing towards the south was observed. D. albomicans showed very high COI haplotype diversity, and had the most phylogeographically structured populations, with differentiation into the northern and the southern population-group, divided by the Kerama gap. Differentiation in host suitability was observed only between highly structured populations of D. albomicans, possibly facilitated by restricted gene flow. Differentiation in host-acceptance in D. takahashii, and host-acceptance and host-choice in L. ryukyuensis was

  4. Molecular characterization and developmental expression pattern of the chicken apolipoprotein D gene: implications for the evolution of vertebrate lipocalins.

    Science.gov (United States)

    Ganfornina, María D; Sánchez, Diego; Pagano, Aldo; Tonachini, Laura; Descalzi-Cancedda, Fiorella; Martínez, Salvador

    2005-01-01

    The insect Lazarillo and the mammalian apolipoprotein D (ApoD) are orthologous members of the lipocalin protein family. We report the cloning and embryonic expression of chicken ApoD, the first molecularly characterized nonmammalian ApoD. We also report the ApoD expression in mouse during postnatal development and some novel aspects of the expression of the paralogous lipocalin prostaglandin D-synthase (PGDS) and discuss these results in view of the lipocalin family evolution in vertebrates. ApoD is expressed in subsets of central nervous system (CNS) neurons and glia during late chicken embryogenesis. Contrary to mouse ApoD, no expression appears in neural crest-derived cephalic mesenchyme and blood vessel pericytes. Also, ApoD is expressed in developing chicken feathers. These expressions are corroborated by quantitative reverse transcriptase-polymerase chain reaction profiles. ApoD is expressed during mouse postnatal development in a subset of CNS neurons, astrocytes and oligodendrocytes, but also in meninges and pericytes. Chicken PGDS is expressed in brain meninges and perivascular cells. Our results suggest that the amniote last common ancestor expressed ApoD and PGDS in the brain during embryogenesis. ApoD appears restricted to ectodermal derivatives, whereas PGDS is expressed by derivatives of the three germ layers.

  5. Classic Maya bloodletting and the cultural evolution of religious rituals: quantifying patterns of variation in hieroglyphic texts.

    Science.gov (United States)

    Munson, Jessica; Amati, Viviana; Collard, Mark; Macri, Martha J

    2014-01-01

    Religious rituals that are painful or highly stressful are hypothesized to be costly signs of commitment essential for the evolution of complex society. Yet few studies have investigated how such extreme ritual practices were culturally transmitted in past societies. Here, we report the first study to analyze temporal and spatial variation in bloodletting rituals recorded in Classic Maya (ca. 250-900 CE) hieroglyphic texts. We also identify the sociopolitical contexts most closely associated with these ancient recorded rituals. Sampling an extensive record of 2,480 hieroglyphic texts, this study identifies every recorded instance of the logographic sign for the word ch'ahb' that is associated with ritual bloodletting. We show that documented rituals exhibit low frequency whose occurrence cannot be predicted by spatial location. Conversely, network ties better capture the distribution of bloodletting rituals across the southern Maya region. Our results indicate that bloodletting rituals by Maya nobles were not uniformly recorded, but were typically documented in association with antagonistic statements and may have signaled royal commitments among connected polities.

  6. Wind patterns as a potential driver in the evolution and maintenance of a North American migratory suture zone.

    Science.gov (United States)

    McCabe, Jennifer D; Olsen, Brian J; Hiebeler, David

    2016-09-01

    Suture zones are areas where range contact zones and hybrid zones of multiple taxa are clustered. Migratory divides, contact zones between divergent populations that breed adjacent to one another but use different migratory routes, are a particular case of suture zones. Although multiple hypotheses for both the formation and maintenance of migratory divides have been suggested, quantitative tests are scarce. Here, we tested whether a novel factor, prevailing winds, was sufficient to explain both the evolution and maintenance of the Cordilleran migratory divide using individual-based models. Empirical observations of eastern birds suggest a circuitous migratory route across Canada before heading south. Western breeders, however, travel south along the Pacific coast to their wintering grounds. We modeled the effect of wind on bird migratory flights by allowing them to float at elevation using spatially explicit modeled wind data. Modeled eastern birds had easterly mean trajectories, whereas western breeders showed significantly more southern trajectories. We also determined that a mean airspeed of 18.5 m s(-1) would be necessary to eliminate this difference in trajectory, a speed that is achieved by waterfowl and shorebirds, but is faster than songbird flight speeds. These results lend support for the potential importance of wind in shaping the phylogeographic history of North American songbirds.

  7. Mechanical Modelling of Pultrusion Process: 2D and 3D Numerical Approaches

    DEFF Research Database (Denmark)

    Baran, Ismet; Hattel, Jesper Henri; Akkerman, Remko

    2015-01-01

    The process induced variations such as residual stresses and distortions are a critical issue in pultrusion, since they affect the structural behavior as well as the mechanical properties and geometrical precision of the final product. In order to capture and investigate these variations......, a mechanical analysis should be performed. In the present work, the two dimensional (2D) quasi-static plane strain mechanical model for the pultrusion of a thick square profile developed by the authors is further improved using generalized plane strain elements. In addition to that, a more advanced 3D thermo......-chemical-mechanical analysis is carried out using 3D quadratic elements which is a novel application for the numerical modelling of the pultrusion process. It is found that the 2D mechanical models give relatively reasonable and accurate stress and displacement evolutions in the transverse direction as compared to the 3D...

  8. Cellular automaton model with dynamical 2D speed-gap relation reproduces empirical and experimental features of traffic flow

    CERN Document Server

    Tian, Junfang; Ma, Shoufeng; Zhu, Chenqiang; Jiang, Rui; Ding, YaoXian

    2015-01-01

    This paper proposes an improved cellular automaton traffic flow model based on the brake light model, which takes into account that the desired time gap of vehicles is remarkably larger than one second. Although the hypothetical steady state of vehicles in the deterministic limit corresponds to a unique relationship between speeds and gaps in the proposed model, the traffic states of vehicles dynamically span a two-dimensional region in the plane of speed versus gap, due to the various randomizations. It is shown that the model is able to well reproduce (i) the free flow, synchronized flow, jam as well as the transitions among the three phases; (ii) the evolution features of disturbances and the spatiotemporal patterns in a car-following platoon; (iii) the empirical time series of traffic speed obtained from NGSIM data. Therefore, we argue that a model can potentially reproduce the empirical and experimental features of traffic flow, provided that the traffic states are able to dynamically span a 2D speed-gap...

  9. Orbifold Reduction and 2d (0,2) Gauge Theories

    CERN Document Server

    Franco, Sebastian; Seong, Rak-Kyeong

    2016-01-01

    We introduce Orbifold Reduction, a new method for generating $2d$ $(0,2)$ gauge theories associated to D1-branes probing singular toric Calabi-Yau 4-folds starting from $4d$ $\\mathcal{N}=1$ gauge theories on D3-branes probing toric Calabi-Yau 3-folds. The new procedure generalizes dimensional reduction and orbifolding. In terms of T-dual configurations, it generates brane brick models starting from brane tilings. Orbifold reduction provides an agile approach for generating $2d$ $(0,2)$ theories with a brane realization. We present three practical applications of the new algorithm: the connection between $4d$ Seiberg duality and $2d$ triality, a combinatorial method for generating theories related by triality and a $2d$ $(0,2)$ generalization of the Klebanov-Witten mass deformation.

  10. Emerging and potential opportunities for 2D flexible nanoelectronics

    Science.gov (United States)

    Zhu, Weinan; Park, Saungeun; Akinwande, Deji

    2016-05-01

    The last 10 years have seen the emergence of two-dimensional (2D) nanomaterials such as graphene, transition metal dichalcogenides (TMDs), and black phosphorus (BP) among the growing portfolio of layered van der Waals thin films. Graphene, the prototypical 2D material has advanced rapidly in device, circuit and system studies that has resulted in commercial large-area applications. In this work, we provide a perspective of the emerging and potential translational applications of 2D materials including semiconductors, semimetals, and insulators that comprise the basic material set for diverse nanosystems. Applications include RF transceivers, smart systems, the so-called internet of things, and neurotechnology. We will review the DC and RF electronic performance of graphene and BP thin film transistors. 2D materials at sub-um channel length have so far enabled cut-off frequencies from baseband to 100GHz suitable for low-power RF and sub-THz concepts.

  11. 2-D electromagnetic simulation of passive microstrip circuits

    CERN Document Server

    Dueñas Jiménez, Alejandro

    2009-01-01

    A reference for circuit design engineers and microwave engineers. It uses a simple 2-D electromagnetic simulation procedure to provide basic knowledge and practical insight into quotidian problems of microstrip passive circuits applied to microwave systems and digital technologies.

  12. 2D gels still have a niche in proteomics

    DEFF Research Database (Denmark)

    Rogowska-Wrzesinska, Adelina; Le Bihan, Marie-Catherine; Thaysen-Andersen, Morten;

    2013-01-01

    ) alternative detection methods for modification specific proteomics; 3) identification of protein isoforms and modified proteins. With an example of the glycoprotein TIMP-1 protein we illustrate the unique properties of 2D gels for the separation and characterisation of multiply modified proteins. We also show......With the rapid advance of MS-based proteomics one might think that 2D gel-based proteomics is dead. This is far from the truth. Current research has shown that there are still a number of places in the field of protein and molecular biology where 2D gels still play a leading role. The aim...... of this review is to highlight some of these applications. Examples from our own research as well as from other published works are used to illustrate the 2D gel driven research in the areas of: 1) de novo sequencing and protein identification from organisms with no or incomplete genome sequences available; 2...

  13. Illumination Compensation for 2-D Barcode Recognition Basing Morphologic

    Directory of Open Access Journals (Sweden)

    Jian-Hua Li

    2013-04-01

    Full Text Available Improvement of image quality has been highly demanded in digital imaging systems. This study presents a novel illumination normalization approach for 2-D barcode recognition under varying lighting conditions. MMs (Morphological transformations are employed to original images using big scale multiple SEs (structuring elements. Then we make use of entropy to fuse images. The performance of proposed methodology is illustrated through the processing of images with different kinds of 2-D barcodes under different backgrounds. The experimental results show that this approach can process different kinds of 2-D barcodes under varying lighting conditions adaptively. Compared with other conventional methods, our proposed approach does a better job in processing 2-D barcode under non-uniform illumination.

  14. Generating a 2D Representation of a Complex Data Structure

    Science.gov (United States)

    James, Mark

    2006-01-01

    A computer program, designed to assist in the development and debugging of other software, generates a two-dimensional (2D) representation of a possibly complex n-dimensional (where n is an integer >2) data structure or abstract rank-n object in that other software. The nature of the 2D representation is such that it can be displayed on a non-graphical output device and distributed by non-graphical means.

  15. Maximizing the Optical Band Gap in 2D Photonic Crystals

    DEFF Research Database (Denmark)

    Hougaard, Kristian G.; Sigmund, Ole

    Topology optimization is used to find the 2D photonic crystal designs with the largest relative photonic band gaps. Starting points for the topology optimization are found with an exhaustive binary search on a low resolution grid.......Topology optimization is used to find the 2D photonic crystal designs with the largest relative photonic band gaps. Starting points for the topology optimization are found with an exhaustive binary search on a low resolution grid....

  16. New design of 2-D photonic crystal waveguide couplers

    Institute of Scientific and Technical Information of China (English)

    ZHONG Zhi-rong; ZHANG Li-hua; YANG Hong-qin; JIANG Yun-kun

    2006-01-01

    @@ Based on couple wave equation and finite-difference time-domain (FDTD) algorithm,the strong couple characteristic of 2-D photonic crystal couplers is calculated.Theoretical analysis and numerical simulated results indicate that the energy in a 2-D photonic crystal coupler can not be totally transferred between two wave-guides.Compared with the result of weak coupling theory,our result is more accurate.

  17. QSAR Models for P-450 (2D6) Substrate Activity

    DEFF Research Database (Denmark)

    Ringsted, Tine; Nikolov, Nikolai Georgiev; Jensen, Gunde Egeskov;

    2009-01-01

    activity relationship (QSAR) modelling systems. They cross validated (leave-groups-out) with concordances of 71%, 81% and 82%, respectively. Discrete organic European Inventory of Existing Commercial Chemical Substances (EINECS) chemicals were screened to predict an approximate percentage of CYP 2D6...... substrates. These chemicals are potentially present in the environment. The biological importance of the CYP 2D6 and the use of the software mentioned above were discussed....

  18. Collins Model and Phase Diagram of 2D Ternary System

    Institute of Scientific and Technical Information of China (English)

    XIE Chuan-Mei; CHEN Li-Rong

    2004-01-01

    The Collins model is introduced into the two-dimensional (2D) alternative ternary system having the Lennard-Jones (L-J) potential. The Gibbs free energy of this ternary system is calculated, and according to thermodynamic theory, a group of equations that determine the solid-liquid diagram of ternary system are derived, some isothermal sectional diagrams of the 2D ternary system are obtained. The results are quite similar to the behavior of three-dimensional substances.

  19. A simultaneous 2D/3D autostereo workstation

    Science.gov (United States)

    Chau, Dennis; McGinnis, Bradley; Talandis, Jonas; Leigh, Jason; Peterka, Tom; Knoll, Aaron; Sumer, Aslihan; Papka, Michael; Jellinek, Julius

    2012-03-01

    We present a novel immersive workstation environment that scientists can use for 3D data exploration and as their everyday 2D computer monitor. Our implementation is based on an autostereoscopic dynamic parallax barrier 2D/3D display, interactive input devices, and a software infrastructure that allows client/server software modules to couple the workstation to scientists' visualization applications. This paper describes the hardware construction and calibration, software components, and a demonstration of our system in nanoscale materials science exploration.

  20. Constructing 2D layered hybrid CdS nanosheets/MoS2 heterojunctions for enhanced visible-light photocatalytic H2 generation

    Science.gov (United States)

    Ma, Song; Xie, Jun; Wen, Jiuqing; He, Kelin; Li, Xin; Liu, Wei; Zhang, Xiangchao

    2017-01-01

    In this work, a 2D hybrid CdS nanosheets(NSs)/MoS2 layered heterojunctions were successfully synthesized by a two-step hydrothermal method and subsequent ultrasonic treatment. The results showed that the loading ultrathin MoS2 NSs as co-catalysts could significantly boost the photocatalytic H2-evolution activity of CdS NSs. It is demonstrated that the optimized 2D CdS NSs/MoS2 (1.0 wt%) layered heterojunctions could achieve the highest photocatalytic H2-evolution activity of 1.75 mmol g-1 h-1 from an aqueous solution containing sulfide and sulfite under visible light, which is 2.03 times as high as that of the pristine CdS NSs. It is believed that the deposition of ultrathin MoS2 NSs and intimate 2D-2D coupling interfaces are mainly responsible for the excellent H2-evolution performance of 2D CdS NSs/MoS2 layered heterojunctions, owing to the effectively promoted separation and transportation of charge carriers and the enhanced following surface H2-evolution kinetics. Interestingly, the lactic acid and formic acid have also been demonstrated to be better sacrificial reagents than the Na2S/Na2SO3, for the photocatalytic H2 evolution over the 2D CdS NSs/MoS2 layered heterojunctions. It is hoped that the strategy of 2D-2D interfacical coupling based on CdS NSs can become a general strategy to improve the H2-evolution activity over various kinds of conventional semiconductor NSs.

  1. Technique of Embedding Depth Maps into 2D Images

    Institute of Scientific and Technical Information of China (English)

    Kazutake Uehira; Hiroshi Unno; Youichi Takashima

    2014-01-01

    This paper proposes a new technique that is used to embed depth maps into corresponding 2-dimensional (2D) images. Since a 2D image and its depth map are integrated into one type of image format, they can be treated as if they were one 2D image. Thereby, it can reduce the amount of data in 3D images by half and simplify the processes for sending them through networks because the synchronization between images for the left and right eyes becomes unnecessary. We embed depth maps in the quantized discrete cosine transform (DCT) data of 2D images. The key to this technique is whether the depth maps could be embedded into 2D images without perceivably deteriorating their quality. We try to reduce their deterioration by compressing the depth map data by using the differences from the next pixel to the left. We assume that there is only one non-zero pixel at most on one horizontal line in the DCT block because the depth map values change abruptly. We conduct an experiment to evaluate the quality of the 2D images embedded with depth maps and find that satisfactory quality could be achieved.

  2. CYP2D6 variability in populations from Venezuela.

    Science.gov (United States)

    Moreno, Nancy; Flores-Angulo, Carlos; Villegas, Cecilia; Mora, Yuselin

    2016-12-01

    CYP2D6 is an important cytochrome P450 enzyme that plays an important role in the metabolism of about 25% of currently prescribed drugs. The presence of polymorphisms in the CYP2D6 gene may modulate enzyme level and activity, thereby affecting individual responses to pharmacological treatments. The most prevalent diseases in the admixed population from Venezuela are cardiovascular and cancer, whereas viral, bacterial and parasitic diseases, particularly malaria, are prevalent in Amerindian populations; in the treatment of these diseases, several drugs that are metabolized by CYP2D6 are used. In this work, we reviewed the data on CYP2D6 variability and predicted metabolizer phenotypes, in healthy volunteers of two admixed and five Amerindian populations from Venezuela. The Venezuelan population is very heterogeneous as a result of the genetic admixture of three major ethnical components: Europeans, Africans and Amerindians. There are noticeable inter-regional and inter-population differences in the process of mixing of this population. Hitherto, there are few published studies in Venezuela on CYP2D6; therefore, it is necessary to increase research in this regard, in particular to develop studies with a larger sample size. There is a considerable amount of work remaining before CYP2D6 is integrated into clinical practice in Venezuela.

  3. Heterochromatin patterns and ribosomal DNA loci distribution in diploid and polyploid Crotalaria species (Leguminosae, Papilionoideae), and inferences on karyotype evolution.

    Science.gov (United States)

    Mondin, Mateus; Aguiar-Perecin, Margarida L R

    2011-09-01

    Most Crotalaria species display a symmetric karyotype with 2n = 16, but 2n = 14 is found in Chrysocalycinae subsection Incanae and 2n = 32 in American species of the section Calycinae. Seven species of the sections Chrysocalycinae, Calycinae, and Crotalaria were analyzed for the identification of heterochromatin types with GC- and AT-specific fluorochromes and chromosomal location of ribosomal DNA loci using fluorescent in situ hybridization (FISH). A major 45S rDNA locus was observed on chromosome 1 in all the species, and a variable number of minor ones were revealed. Only one 5S rDNA locus was observed in the species investigated. Chromomycin A(3) (CMA) revealed CMA(+) bands colocalized with most rDNA loci, small bands unrelated to ribosomal DNA on two chromosome pairs in Crotalaria incana, and CMA(+) centromeric bands that were quenched by distamycin A were detected in species of Calycinae and Crotalaria sections. DAPI(+) bands were detected in C. incana. The results support the species relationships based on flower specialization and were useful for providing insight into mechanisms of karyotype evolution. The heterochromatin types revealed by fluorochromes suggest the occurrence of rearrangements in repetitive DNA families in these heterochromatic blocks during species diversification. This DNA sequence turnover and the variability in number/position of rDNA sites could be interpreted as resulting from unequal crossing over and (or) transposition events. The occurrence of only one 5S rDNA locus and the smaller chromosome size in the polyploids suggest that DNA sequence losses took place following polyploidization events.

  4. Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC

    Directory of Open Access Journals (Sweden)

    Engelen Stefan

    2012-02-01

    Full Text Available Abstract Background Bacterial genomes displaying a strong bias between the leading and the lagging strand of DNA replication encode two DNA polymerases III, DnaE and PolC, rather than a single one. Replication is a highly unsymmetrical process, and the presence of two polymerases is therefore not unexpected. Using comparative genomics, we explored whether other processes have evolved in parallel with each polymerase. Results Extending previous in silico heuristics for the analysis of gene co-evolution, we analyzed the function of genes clustering with dnaE and polC. Clusters were highly informative. DnaE co-evolves with the ribosome, the transcription machinery, the core of intermediary metabolism enzymes. It is also connected to the energy-saving enzyme necessary for RNA degradation, polynucleotide phosphorylase. Most of the proteins of this co-evolving set belong to the persistent set in bacterial proteomes, that is fairly ubiquitously distributed. In contrast, PolC co-evolves with RNA degradation enzymes that are present only in the A+T-rich Firmicutes clade, suggesting at least two origins for the degradosome. Conclusion DNA replication involves two machineries, DnaE and PolC. DnaE co-evolves with the core functions of bacterial life. In contrast PolC co-evolves with a set of RNA degradation enzymes that does not derive from the degradosome identified in gamma-Proteobacteria. This suggests that at least two independent RNA degradation pathways existed in the progenote community at the end of the RNA genome world.

  5. Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity

    Science.gov (United States)

    Lyons, Robert P.; Scholz, Christopher A.; Cohen, Andrew S.; King, John W.; Brown, Erik T.; Ivory, Sarah J.; Johnson, Thomas C.; Deino, Alan L.; Reinthal, Peter N.; McGlue, Michael M.; Blome, Margaret W.

    2015-12-01

    The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9-15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world's largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species.

  6. Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network.

    Directory of Open Access Journals (Sweden)

    François Lapraz

    2009-11-01

    Full Text Available Formation of the dorsal-ventral axis of the sea urchin embryo relies on cell interactions initiated by the TGFbeta Nodal. Intriguingly, although nodal expression is restricted to the ventral side of the embryo, Nodal function is required for specification of both the ventral and the dorsal territories and is able to restore both ventral and dorsal regions in nodal morpholino injected embryos. The molecular basis for the long-range organizing activity of Nodal is not understood. In this paper, we provide evidence that the long-range organizing activity of Nodal is assured by a relay molecule synthesized in the ventral ectoderm, then translocated to the opposite side of the embryo. We identified this relay molecule as BMP2/4 based on the following arguments. First, blocking BMP2/4 function eliminated the long-range organizing activity of an activated Nodal receptor in an axis rescue assay. Second, we demonstrate that BMP2/4 and the corresponding type I receptor Alk3/6 functions are both essential for specification of the dorsal region of the embryo. Third, using anti-phospho-Smad1/5/8 immunostaining, we show that, despite its ventral transcription, the BMP2/4 ligand triggers receptor mediated signaling exclusively on the dorsal side of the embryo, one of the most extreme cases of BMP translocation described so far. We further report that the pattern of pSmad1/5/8 is graded along the dorsal-ventral axis and that two BMP2/4 target genes are expressed in nested patterns centered on the region with highest levels of pSmad1/5/8, strongly suggesting that BMP2/4 is acting as a morphogen. We also describe the very unusual ventral co-expression of chordin and bmp2/4 downstream of Nodal and demonstrate that Chordin is largely responsible for the spatial restriction of BMP2/4 signaling to the dorsal side. Thus, unlike in most organisms, in the sea urchin, a single ventral signaling centre is responsible for induction of ventral and dorsal cell fates. Finally

  7. Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network.

    Science.gov (United States)

    Lapraz, François; Besnardeau, Lydia; Lepage, Thierry

    2009-11-01

    Formation of the dorsal-ventral axis of the sea urchin embryo relies on cell interactions initiated by the TGFbeta Nodal. Intriguingly, although nodal expression is restricted to the ventral side of the embryo, Nodal function is required for specification of both the ventral and the dorsal territories and is able to restore both ventral and dorsal regions in nodal morpholino injected embryos. The molecular basis for the long-range organizing activity of Nodal is not understood. In this paper, we provide evidence that the long-range organizing activity of Nodal is assured by a relay molecule synthesized in the ventral ectoderm, then translocated to the opposite side of the embryo. We identified this relay molecule as BMP2/4 based on the following arguments. First, blocking BMP2/4 function eliminated the long-range organizing activity of an activated Nodal receptor in an axis rescue assay. Second, we demonstrate that BMP2/4 and the corresponding type I receptor Alk3/6 functions are both essential for specification of the dorsal region of the embryo. Third, using anti-phospho-Smad1/5/8 immunostaining, we show that, despite its ventral transcription, the BMP2/4 ligand triggers receptor mediated signaling exclusively on the dorsal side of the embryo, one of the most extreme cases of BMP translocation described so far. We further report that the pattern of pSmad1/5/8 is graded along the dorsal-ventral axis and that two BMP2/4 target genes are expressed in nested patterns centered on the region with highest levels of pSmad1/5/8, strongly suggesting that BMP2/4 is acting as a morphogen. We also describe the very unusual ventral co-expression of chordin and bmp2/4 downstream of Nodal and demonstrate that Chordin is largely responsible for the spatial restriction of BMP2/4 signaling to the dorsal side. Thus, unlike in most organisms, in the sea urchin, a single ventral signaling centre is responsible for induction of ventral and dorsal cell fates. Finally, we show that

  8. Evaluation of low-dose limits in 3D-2D rigid registration for surgical guidance

    Science.gov (United States)

    Uneri, A.; Wang, A. S.; Otake, Y.; Kleinszig, G.; Vogt, S.; Khanna, A. J.; Gallia, G. L.; Gokaslan, Z. L.; Siewerdsen, J. H.

    2014-09-01

    An algorithm for intensity-based 3D-2D registration of CT and C-arm fluoroscopy is evaluated for use in surgical guidance, specifically considering the low-dose limits of the fluoroscopic x-ray projections. The registration method is based on a framework using the covariance matrix adaptation evolution strategy (CMA-ES) to identify the 3D patient pose that maximizes the gradient information similarity metric. Registration performance was evaluated in an anthropomorphic head phantom emulating intracranial neurosurgery, using target registration error (TRE) to characterize accuracy and robustness in terms of 95% confidence upper bound in comparison to that of an infrared surgical tracking system. Three clinical scenarios were considered: (1) single-view image + guidance, wherein a single x-ray projection is used for visualization and 3D-2D guidance; (2) dual-view image + guidance, wherein one projection is acquired for visualization, combined with a second (lower-dose) projection acquired at a different C-arm angle for 3D-2D guidance; and (3) dual-view guidance, wherein both projections are acquired at low dose for the purpose of 3D-2D guidance alone (not visualization). In each case, registration accuracy was evaluated as a function of the entrance surface dose associated with the projection view(s). Results indicate that images acquired at a dose as low as 4 μGy (approximately one-tenth the dose of a typical fluoroscopic frame) were sufficient to provide TRE comparable or superior to that of conventional surgical tracking, allowing 3D-2D guidance at a level of dose that is at most 10% greater than conventional fluoroscopy (scenario #2) and potentially reducing the dose to approximately 20% of the level in a conventional fluoroscopically guided procedure (scenario #3).

  9. Soil evolution dynamics and cultural response: Transformation of habitation patterns in the southern Netherlands (1000 BC-500 AD)

    Science.gov (United States)

    Roymans, Nico; Kluiving, Sjoerd; Bekkema, Marijke; van Puijenbroek, Florens

    2013-04-01

    Long-term archaeological data gathering in the southern Netherlands may deliver an interesting scale model that is suitable for the Pleistocene sand areas of the Northwest European Plain. On a micro-scale level it has become clear that Bronze Age and Iron Age farmers intensively used the landscape, resulting in relatively dense distribution patterns of settlements all over the sand plateaus. However, this agricultural use of the landscape - related to the 'celtic field' system - led to a process of soil degeneration during which initially brown moder podzols gradually transformed into degenerated humus podzols that could no longer be used as farmland. According to established 'models', this process of 'secondary podzolisation' particularly affected those sections of the landscape that were dominated by dry sandy soils with a low loam content (between c. 10 and 20%). In the later Iron Age the changing soil conditions resulted in a dramatic shift in the habitation pattern that clearly manifests itself in the Roman period; on the local scale the habitation moved from the degenerated soils to nearby zones with better soil conditions (higher loam content), which became more densely inhabited now than in the Bronze Age/Early Iron Age. The zones where the Roman period settlements concentrated became also the zones where we can find the early medieval habitation and where in the late medieval period the plaggen soils started to develop. Measured loam values of soil samples (n=181) in Veldhoven, southern Netherlands, are in agreement with the described model that the plaggen cover is located on soils containing high loam% and that humus podzolsoils of former heath areas have low loam content. Local spatial as well as vertical variations in loam content of sand layers is shown to occur, warning against single parameter research. Other potential causes for the deviation of the model are: a) the impact of fluctuating groundwater levels, b) impact of older formations with

  10. Evolution and biogeography of an emerging quasispecies: diversity patterns of the fish Viral Hemorrhagic Septicemia virus (VHSv).

    Science.gov (United States)

    Pierce, Lindsey R; Stepien, Carol A

    2012-05-01

    Viral Hemorrhagic Septicemia virus (VHSv) is an RNA rhabdovirus that causes one of the most important finfish diseases, affecting over 70 marine and freshwater species. It was discovered in European cultured fish in 1938 and since has been described across the Northern Hemisphere. Four strains and several substrains have been hypothesized, whose phylogenetic relationships and evolutionary radiation are evaluated here in light of a quasispecies model, including an in-depth analysis of the novel and especially virulent new substrain (IVb) that first appeared in the North American Laurentian Great Lakes in 2003. We analyze the evolutionary patterns, genetic diversity, and biogeography of VHSv using all available RNA sequences from the glycoprotein (G), nucleoprotein (N), and non-virion (Nv) genes, with Maximum Likelihood and bayesian approaches. Results indicate that the G gene evolves at an estimated rate of μ=2.58×10(-4) nucleotide substitutions per site per year, the N gene at μ=4.26×10(-4), and Nv fastest at μ=1.25×10(-3). Phylogenetic trees from the three genes largely are congruent, distinguishing strains I-IV as reciprocally monophyletic with high bootstrap and posterior probability support. VHSv appears to have originated from a marine ancestor in the North Atlantic Ocean, diverging into two primary clades: strain IV in North America (the Northwestern Atlantic Ocean), and strains I-III in the Northeastern Atlantic region (Europe). Strain II may comprise the basal group of the latter clade and diverged in Baltic Sea estuarine waters; strains I and III appear to be sister groups (according to the G and Nv genes), with the former mostly in European freshwaters and the latter in North Sea marine/estuarine waters. Strain IV is differentiated into three monophyletic substrains, with IVa infecting Northeastern Pacific salmonids and many marine fishes (with 44 unique G gene haplotypes), IVb endemic to the freshwater Great Lakes (11 haplotypes), and a newly

  11. Evolution of central pattern generators for the control of a five-link planar bipedal walking mechanism

    CERN Document Server

    Baydin, Atilim Gunes

    2008-01-01

    With the aim of producing a stable human-like bipedal gait, a five-link planar walking mechanism was coupled with a central pattern generator (CPG) network, consisting of units based on Matsuoka's half-center oscillator model. As a minimalistic approach to bipedal walking, this type of walking mechanism contains only four actuators (two in the hip joints and two in the knee joints), and is lacking feet and ankles. Firstly, the mechanism was designed and built as a physical simulation programmed from scratch, providing a platform for hand-tuned tests and the creation of a CPG controller by genetic algorithms (GA). The oscillatory characteristics of the CPG network together with its internal connection structure and the feedback pathways from the environment were subject to GA optimization. The approach proved successful and the results were then transferred to a hardware realization of the five-link walking mechanism, to test how well these perform under real-world dynamics. Results suggest that the biological...

  12. Intercalation of organic molecules in 2D copper (II) nitroprusside: Intermolecular interactions and magnetic properties

    Energy Technology Data Exchange (ETDEWEB)

    Osiry, H.; Cano, A.; Lemus-Santana, A.A.; Rodríguez, A. [Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Unidad Legaria, Instituto Politécnico Nacional (Mexico); Carbonio, R.E. [INFIQC-CONICET, Departamento de Físico Química, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA Córdoba (Argentina); Reguera, E., E-mail: edilso.reguera@gmail.com [Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Unidad Legaria, Instituto Politécnico Nacional (Mexico)

    2015-10-15

    This contribution discusses the intercalation of imidazole and its 2-ethyl derivative, and pyridine in 2D copper nitroprusside. In the interlayer region, neighboring molecules remain interacting throu gh their dipole and quadrupole moments, which supports the solid 3D crystal structure. The crystal structure of this series of intercalation compounds was solved and refined from powder X-ray diffraction patterns complemented with spectroscopic information. The intermolecular interactions were studied from the refined crystal structures and low temperature magnetic measurements. Due to strong attractive forces between neighboring molecules, the resulting π–π cloud overlapping enables the ferromagnetic coupling between metal centers on neighboring layers, which was actually observed for the solids containing imidazole and pyridine as intercalated molecules. For these two solids, the magnetic data were properly described with a model of six neighbors. For the solid containing 2-ethylimidazole and for 2D copper nitroprusside, a model of four neighbors in a plane is sufficient to obtain a reliable data fitting. - Highlights: • Intercalation of organic molecules in 2D copper (II) nitroprusside. • Molecular properties of intercalation compounds of 2D copper (II) nitroprusside. • Magnetic properties of hybrid inorganic–organic solids. • Hybrid inorganic–organic 3D framework.

  13. Patterns of structural dynamics in RACK1 protein retained throughout evolution: A hydrogen-deuterium exchange study of three orthologs

    Science.gov (United States)

    Tarnowski, Krzysztof; Fituch, Kinga; Szczepanowski, Roman H; Dadlez, Michal; Kaus-Drobek, Magdalena

    2014-01-01

    RACK1 is a member of the WD repeat family of proteins and is involved in multiple fundamental cellular processes. An intriguing feature of RACK1 is its ability to interact with at least 80 different protein partners. Thus, the structural features enabling such interactomic flexibility are of great interest. Several previous studies of the crystal structures of RACK1 orthologs described its detailed architecture and confirmed predictions that RACK1 adopts a seven-bladed β-propeller fold. However, this did not explain its ability to bind to multiple partners. We performed hydrogen-deuterium (H-D) exchange mass spectrometry on three orthologs of RACK1 (human, yeast, and plant) to obtain insights into the dynamic properties of RACK1 in solution. All three variants retained similar patterns of deuterium uptake, with some pronounced differences that can be attributed to RACK1's divergent biological functions. In all cases, the most rigid structural elements were confined to B-C turns and, to some extent, strands B and C, while the remaining regions retained much flexibility. We also compared the average rate constants for H-D exchange in different regions of RACK1 and found that amide protons in some regions exchanged at least 1000-fold faster than in others. We conclude that its evolutionarily retained structural architecture might have allowed RACK1 to accommodate multiple molecular partners. This was exemplified by our additional analysis of yeast RACK1 dimer, which showed stabilization, as well as destabilization, of several interface regions upon dimer formation. PMID:24591271

  14. Patterns of structural dynamics in RACK1 protein retained throughout evolution: a hydrogen-deuterium exchange study of three orthologs.

    Science.gov (United States)

    Tarnowski, Krzysztof; Fituch, Kinga; Szczepanowski, Roman H; Dadlez, Michal; Kaus-Drobek, Magdalena

    2014-05-01

    RACK1 is a member of the WD repeat family of proteins and is involved in multiple fundamental cellular processes. An intriguing feature of RACK1 is its ability to interact with at least 80 different protein partners. Thus, the structural features enabling such interactomic flexibility are of great interest. Several previous studies of the crystal structures of RACK1 orthologs described its detailed architecture and confirmed predictions that RACK1 adopts a seven-bladed β-propeller fold. However, this did not explain its ability to bind to multiple partners. We performed hydrogen-deuterium (H-D) exchange mass spectrometry on three orthologs of RACK1 (human, yeast, and plant) to obtain insights into the dynamic properties of RACK1 in solution. All three variants retained similar patterns of deuterium uptake, with some pronounced differences that can be attributed to RACK1's divergent biological functions. In all cases, the most rigid structural elements were confined to B-C turns and, to some extent, strands B and C, while the remaining regions retained much flexibility. We also compared the average rate constants for H-D exchange in different regions of RACK1 and found that amide protons in some regions exchanged at least 1000-fold faster than in others. We conclude that its evolutionarily retained structural architecture might have allowed RACK1 to accommodate multiple molecular partners. This was exemplified by our additional analysis of yeast RACK1 dimer, which showed stabilization, as well as destabilization, of several interface regions upon dimer formation.

  15. 2D Numerical simulations of intraoceanic subduction: the case study of the Ligurian Alps.

    Science.gov (United States)

    Malatesta, Cristina; Gerya, Taras; Federico, Laura; Scambelluri, Marco; Crispini, Laura; Capponi, Giovanni

    2010-05-01

    Intraoceanic subduction is an important part of the present and past subduction systems, and some features of such process are not yet fully understood. We therefore studied intraoceanic subduction zones with the help of 2D numerical models, analyzing the parameters influencing their evolution in time and space. We applied the finite differences method on a rectangular grid, to calculate properties such as pressure, temperatures and velocities inside the models solving a set of equations. The latter comprise the Stokes equation of motion, the continuity equation and the heat transport equation. Temperature and velocities are computed on the nodes of the grid whereas pressures are calculated for the geometrical centers of the cells. We defined material properties such as density or viscosity on marker points, initially positioned on a regular rectangular grid. The markers and therefore the material properties are moved through the mesh according to the velocity field using the forth order Runge-Kutta method (Gerya et al. 2002). Subduction is forced to begin at a weak zone in the lithospheric mantle within an oceanic basin of prescribed width. The effect of different arrangements of rock bodies inside the subducting lithosphere on the evolution of the process was carefully analyzed. In particular we reproduced two distinct structures of the oceanic lithosphere: i) the layered oceanic crust made up of a stratified succession typical of fast-spreading ridges and ii) the oceanic lithosphere typical of slow and ultra-slow spreading centers, where an incomplete sequence is observable. The latter structure lacks a sheeted dike complex, has a low volume of gabbros and basalts and gabbros form discrete intrusions in variably serpentinized peridotites (Lagabrielle et al., 1997; Mével, 2003). Such an "heterogeneous" structure is characteristic of the Alpine and Appennine ophiolites that characterized the Mesozoic Ligurian Tethys located between Europe and Adria. The depth of

  16. Developmental evolution of flowering plant pollen tube cell walls: callose synthase (CalS gene expression patterns

    Directory of Open Access Journals (Sweden)

    Abercrombie Jason M

    2011-07-01

    and pollen-specific functions in early seed plants and was then recruited to novel expression patterns and functions within pollen tube walls in an ancestor of extant angiosperms.

  17. IGUANA A high-performance 2D and 3D visualisation system

    CERN Document Server

    Alverson, G; Muzaffar, S; Osborne, I; Taylor, L; Tuura, L A

    2004-01-01

    The IGUANA project has developed visualisation tools for multiple high-energy experiments. At the core of IGUANA is a generic, high- performance visualisation system based on OpenInventor and OpenGL. This paper describes the back-end and a feature-rich 3D visualisation system built on it, as well as a new 2D visualisation system that can automatically generate 2D views from 3D data, for example to produce R/Z or X/Y detector displays from existing 3D display with little effort. IGUANA has collaborated with the open-source gl2ps project to create a high-quality vector postscript output that can produce true vector graphics output from any OpenGL 2D or 3D display, complete with surface shading and culling of invisible surfaces. We describe how it works. We also describe how one can measure the memory and performance costs of various OpenInventor constructs and how to test scene graphs. We present good patterns to follow and bad patterns to avoid. We have added more advanced tools such as per-object clipping, sl...

  18. The NH$_2$D hyperfine structure revealed by astrophysical observations

    CERN Document Server

    Daniel, F; Punanova, A; Harju, J; Faure, A; Roueff, E; Sipilä, O; Caselli, P; Güsten, R; Pon, A; Pineda, J E

    2016-01-01

    The 1$_{11}$-1$_{01}$ lines of ortho and para--NH$_2$D (o/p-NH$_2$D), respectively at 86 and 110 GHz, are commonly observed to provide constraints on the deuterium fractionation in the interstellar medium. In cold regions, the hyperfine structure due to the nitrogen ($^{14}$N) nucleus is resolved. To date, this splitting is the only one which is taken into account in the NH$_2$D column density estimates. We investigate how the inclusion of the hyperfine splitting caused by the deuterium (D) nucleus affects the analysis of the rotational lines of NH$_2$D. We present 30m IRAM observations of the above mentioned lines, as well as APEX o/p-NH$_2$D observations of the 1$_{01}$-0$_{00}$ lines at 333 GHz. The hyperfine spectra are first analyzed with a line list that only includes the hyperfine splitting due to the $^{14}$N nucleus. We find inconsistencies between the line widths of the 1$_{01}$-0$_{00}$ and 1$_{11}$-1$_{01}$ lines, the latter being larger by a factor of $\\sim$1.6$\\pm0.3$. Such a large difference is...

  19. 2D nanostructures for water purification: graphene and beyond.

    Science.gov (United States)

    Dervin, Saoirse; Dionysiou, Dionysios D; Pillai, Suresh C

    2016-08-18

    Owing to their atomically thin structure, large surface area and mechanical strength, 2D nanoporous materials are considered to be suitable alternatives for existing desalination and water purification membrane materials. Recent progress in the development of nanoporous graphene based materials has generated enormous potential for water purification technologies. Progress in the development of nanoporous graphene and graphene oxide (GO) membranes, the mechanism of graphene molecular sieve action, structural design, hydrophilic nature, mechanical strength and antifouling properties and the principal challenges associated with nanopore generation are discussed in detail. Subsequently, the recent applications and performance of newly developed 2D materials such as 2D boron nitride (BN) nanosheets, graphyne, molybdenum disulfide (MoS2), tungsten chalcogenides (WS2) and titanium carbide (Ti3C2Tx) are highlighted. In addition, the challenges affecting 2D nanostructures for water purification are highlighted and their applications in the water purification industry are discussed. Though only a few 2D materials have been explored so far for water treatment applications, this emerging field of research is set to attract a great deal of attention in the near future.

  20. Twin characterisation using 2D and 3D EBSD

    Institute of Scientific and Technical Information of China (English)

    M. D. NAVE; J. J. L. MULDERS; A. GHOLINIA

    2005-01-01

    Electron backscatter diffraction (EBSD) is a superior technique for twin characterisation due to its ability to provide highly detailed classification (by generation, system and variant) of a significant number of twins in a relatively short time. 2D EBSD is now widely used for twin characterisation and provides quite good estimates of twin volume fractions under many conditions. Nevertheless, its accuracy is limited by assumptions that have to be made due to the 2D nature of the technique. With 3D EBSD, two key assumptions are no longer required, as additional information can be derived from the 3D map. This paper compares the benefits and limitations of 2D and 3D EBSD for twin characterisation. 2D EBSD enables a larger number of twins to be mapped in a given space of time, giving better statistics. 3D EBSD provides more comprehensive twin characterisation and will be a valuable tool for validation of 2D stereological methods and microstructural models of twinning during deformation.

  1. New Reductions and Nonlinear Systems for 2D Schrodinger Operators

    CERN Document Server

    Mironov, A

    2010-01-01

    New Completely Integrable (2+1)-System is studied. It is based on the so-called L-A-B-triples $L_t=[H,L]-fL$ where L is a 2D Schrodinger Operator. This approach was invented by S.Manakov and B.Dubrovin, I.Krichever, S.Novikov(DKN) in the works published in 1976. A nonstandard reduction for the 2D Schrodinger Operator (completely different from the one found by S.Novikov and A.Veselov in 1984) compatible with time dynamics of the new Nonlinear System, is studied here. It can be naturally treated as a 2D extension of the famous Burgers System. The Algebro-Geometric (AG) Periodic Solutions here are very specific and unusual (for general and reduced cases). The reduced system is linearizable like Burgers. However, the general one (and probably the reduced one also) certainly lead in the stationary AG case to the nonstandard examples of algebraic curves $\\Gamma\\subset W$ in the full complex 2D manifold of Bloch-Floquet functions W for the periodic elliptic 2D operator H where $H\\psi(x,y,P)=\\lambda(P)\\psi(x,y,P),P\\...

  2. Failure Mechanism of True 2D Granular Flows

    CERN Document Server

    Nguyen, Cuong T; Fukagawa, R

    2015-01-01

    Most previous experimental investigations of two-dimensional (2D) granular column collapses have been conducted using three-dimensional (3D) granular materials in narrow horizontal channels (i.e., quasi-2D condition). Our recent research on 2D granular column collapses by using 2D granular materials (i.e., aluminum rods) has revealed results that differ markedly from those reported in the literature. We assume a 2D column with an initial height of h0 and initial width of d0, a defined as their ratio (a =h0/d0), a final height of h , and maximum run-out distance of d . The experimental data suggest that for the low a regime (a 0.65), the ratio of a to (d-d0)/d0, h0/h , or d/d0 is expressed by power-law relations. In particular, the following power-function ratios (h0/h=1.42a^2/3 and d/d0=4.30a^0.72) are proposed for every a >0.65. In contrast, the ratio (d-d0)/d0=3.25a^0.96 only holds for 0.651.5. In addition, the influence of ground contact surfaces (hard or soft beds) on the final run-out distance and destru...

  3. Probing S-state advancements and recombination pathways in photosystem II with a global fit program for flash-induced oxygen evolution pattern.

    Science.gov (United States)

    Pham, Long Vo; Messinger, Johannes

    2016-06-01

    The oxygen-evolving complex (OEC) in photosystem II catalyzes the oxidation of water to molecular oxygen. Four decades ago, measurements of flash-induced oxygen evolution have shown that the OEC steps through oxidation states S(0), S(1), S(2), S(3) and S(4) before O(2) is released and the S(0) state is reformed. The light-induced transitions between these states involve misses and double hits. While it is widely accepted that the miss parameter is S state dependent and may be further modulated by the oxidation state of the acceptor side, the traditional way of analyzing each flash-induced oxygen evolution pattern (FIOP) individually did not allow using enough free parameters to thoroughly test this proposal. Furthermore, this approach does not allow assessing whether the presently known recombination processes in photosystem II fully explain all measured oxygen yields during Si state lifetime measurements. Here we present a global fit program that simultaneously fits all flash-induced oxygen yields of a standard FIOP (2 Hz flash frequency) and of 11-18 FIOPs each obtained while probing the S(0), S(2) and S(3) state lifetimes in spinach thylakoids at neutral pH. This comprehensive data treatment demonstrates the presence of a very slow phase of S(2) decay, in addition to the commonly discussed fast and slow reduction of S(2) by YD and QB(-), respectively. Our data support previous suggestions that the S(0)→S(1) and S(1)→S(2) transitions involve low or no misses, while high misses occur in the S(2)→S(3) or S(3)→S(0) transitions.

  4. The four hexamerin genes in the honey bee: structure, molecular evolution and function deduced from expression patterns in queens, workers and drones

    Directory of Open Access Journals (Sweden)

    Martins Juliana R

    2010-03-01

    Full Text Available Abstract Background Hexamerins are hemocyanin-derived proteins that have lost the ability to bind copper ions and transport oxygen; instead, they became storage proteins. The current study aimed to broaden our knowledge on the hexamerin genes found in the honey bee genome by exploring their structural characteristics, expression profiles, evolution, and functions in the life cycle of workers, drones and queens. Results The hexamerin genes of the honey bee (hex 70a, hex 70b, hex 70c and hex 110 diverge considerably in structure, so that the overall amino acid identity shared among their deduced protein subunits varies from 30 to 42%. Bioinformatics search for motifs in the respective upstream control regions (UCRs revealed six overrepresented motifs including a potential binding site for Ultraspiracle (Usp, a target of juvenile hormone (JH. The expression of these genes was induced by topical application of JH on worker larvae. The four genes are highly transcribed by the larval fat body, although with significant differences in transcript levels, but only hex 110 and hex 70a are re-induced in the adult fat body in a caste- and sex-specific fashion, workers showing the highest expression. Transcripts for hex 110, hex 70a and hex70b were detected in developing ovaries and testes, and hex 110 was highly transcribed in the ovaries of egg-laying queens. A phylogenetic analysis revealed that HEX 110 is located at the most basal position among the holometabola hexamerins, and like HEX 70a and HEX 70c, it shares potential orthology relationship with hexamerins from other hymenopteran species. Conclusions Striking differences were found in the structure and developmental expression of the four hexamerin genes in the honey bee. The presence of a potential binding site for Usp in the respective 5' UCRs, and the results of experiments on JH level manipulation in vivo support the hypothesis of regulation by JH. Transcript levels and patterns in the fat body

  5. Joint 2-D DOA and Noncircularity Phase Estimation Method

    Directory of Open Access Journals (Sweden)

    Wang Ling

    2012-03-01

    Full Text Available Classical joint estimation methods need large calculation quantity and multidimensional search. In order to avoid these shortcoming, a novel joint two-Dimension (2-D Direction Of Arrival (DOA and noncircularity phase estimation method based on three orthogonal linear arrays is proposed. The problem of 3-D parameter estimation can be transformed to three parallel 2-D parameter estimation according to the characteristic of three orthogonal linear arrays. Further more, the problem of 2-D parameter estimation can be transformed to 1-D parameter estimation by using the rotational invariance property among signal subspace and orthogonal property of noise subspace at the same time in every subarray. Ultimately, the algorithm can realize joint estimation and pairing parameters by one eigen-decomposition of extended covariance matrix. The proposed algorithm can be applicable for low SNR and small snapshot scenarios, and can estiame 2(M −1 signals. Simulation results verify that the proposed algorithm is effective.

  6. Genetics, genomics, and evolutionary biology of NKG2D ligands.

    Science.gov (United States)

    Carapito, Raphael; Bahram, Seiamak

    2015-09-01

    Human and mouse NKG2D ligands (NKG2DLs) are absent or only poorly expressed by most normal cells but are upregulated by cell stress, hence, alerting the immune system in case of malignancy or infection. Although these ligands are numerous and highly variable (at genetic, genomic, structural, and biochemical levels), they all belong to the major histocompatibility complex class I gene superfamily and bind to a single, invariant, receptor: NKG2D. NKG2D (CD314) is an activating receptor expressed on NK cells and subsets of T cells that have a key role in the recognition and lysis of infected and tumor cells. Here, we review the molecular diversity of NKG2DLs, discuss the increasing appreciation of their roles in a variety of medical conditions, and propose several explanations for the evolutionary force(s) that seem to drive the multiplicity and diversity of NKG2DLs while maintaining their interaction with a single invariant receptor.

  7. Cluster algebras in Scattering Amplitudes with special 2D kinematics

    CERN Document Server

    Torres, Marcus A C

    2013-01-01

    We study the cluster algebra of the kinematic configuration space $Conf_n(\\mathbb{P}^3)$ of a n-particle scattering amplitude restricted to the special 2D kinematics. We found that the n-points two loop MHV remainder function found in special 2D kinematics depend on a selection of \\XX-coordinates that are part of a special structure of the cluster algebra related to snake triangulations of polygons. This structure forms a necklace of hypercubes beads in the corresponding Stasheff polytope. Furthermore in $n = 12$, the cluster algebra and the selection of \\XX-coordinates in special 2D kinematics replicates the cluster algebra and the selection of \\XX-coordinates of $n=6$ two loop MHV amplitude in 4D kinematics.

  8. Simultaneous 2D Strain Sensing Using Polymer Planar Bragg Gratings

    Directory of Open Access Journals (Sweden)

    Manuel Rosenberger

    2015-02-01

    Full Text Available We demonstrate the application of polymer planar Bragg gratings for multi-axial strain sensing and particularly highlight simultaneous 2D strain measurement. A polymer planar Bragg grating (PPBG fabricated with a single writing step in bulk polymethylmethacrylate is used for measuring both tensile and compressive strain at various angles. It is shown that the sensitivity of the PPBG strongly depends on the angle between the optical waveguide into which the grating is inscribed and the direction along which the mechanical load is applied. Additionally, a 2D PPBG fabricated by writing two Bragg gratings angularly displaced from each other into a single polymer platelet is bonded to a stainless steel plate. The two reflected wavelengths exhibit different sensitivities while tested toward tensile and compressive strain. These characteristics make 2D PPBG suitable for measuring multi-axial tensile and compressive strain.

  9. Design and Realization of Dynamic Obstacle on URWPSSim2D

    Directory of Open Access Journals (Sweden)

    Xiao Chen

    2013-07-01

    Full Text Available Simulation system is charged with the strategy validation and dual team meets, and as the 2-dimensional simulation platform for underwater robotic fish game, URWPGSim2D is the assigned platform for Chinese underwater robot contest and Robot cup underwater program. By now on URWPGSim2D, there is only static obstacles,thus short of changeableness. In order to improve the changeableness and innovation of robotic fish contest, to extend the space for the programming of contest strategy, and to increase the interest, this paper study the design of dynamic obstacles on URWPGSim2D, and design and implement two kinds of dynamic obstacles, which are the evadible dynamic obstacle and the forcing dribbling obstacle.  

  10. Applications of Doppler Tomography in 2D and 3D

    Science.gov (United States)

    Richards, M.; Budaj, J.; Agafonov, M.; Sharova, O.

    2010-12-01

    Over the past few years, the applications of Doppler tomography have been extended beyond the usual calculation of 2D velocity images of circumstellar gas flows. This technique has now been used with the new Shellspec spectrum synthesis code to demonstrate the effective modeling of the accretion disk and gas stream in the TT Hya Algol binary. The 2D tomography procedure projects all sources of emission onto a single central (Vx, Vy) velocity plane even though the gas is expected to flow beyond that plane. So, new 3D velocity images were derived with the Radioastronomical Approach method by assuming a grid of Vz values transverse to the central 2D plane. The 3D approach has been applied to the U CrB and RS Vul Algol-type binaries to reveal substantial flow structures beyond the central velocity plane.

  11. UPLAND EROSION MODELING WITH CASC2D-SED

    Institute of Scientific and Technical Information of China (English)

    Pierre JULIEN; Rosalía ROJAS

    2002-01-01

    Developed at Colorado State University, CASC2D-SED is a physically-based model simulating the hydrologic response of a watershed to a distributed rainfall field. The time-dependent processes include:precipitation, interception, infiltration, surface runoff and channel routing, upland erosion, transport and sedimentation. CASC2D-SED is applied to Goodwin Creek, Mississippi. The watershed covers 21 km2and has been extensively monitored both at the outlet and at several internal locations by the ARS-NSL at Oxford, MS. The model has been calibrated and validated using rainfall data from 16 meteorological stations, 6 stream gauging stations and 6 sediment gauging stations. Sediment erosion/deposition rates by size fraction are predicted both in space and time. Geovisualization, a powerful data exploration technique based on GIS technology, is used to analyze and display the dynamic output time series generated by the CASC2D-SED model.

  12. Chemical Sensing of 2D Graphene/MoS2 Heterostructure device.

    Science.gov (United States)

    Cho, Byungjin; Yoon, Jongwon; Lim, Sung Kwan; Kim, Ah Ra; Kim, Dong-Ho; Park, Sung-Gyu; Kwon, Jung-Dae; Lee, Young-Joo; Lee, Kyu-Hwan; Lee, Byoung Hun; Ko, Heung Cho; Hahm, Myung Gwan

    2015-08-05

    We report the production of a two-dimensional (2D) heterostructured gas sensor. The gas-sensing characteristics of exfoliated molybdenum disulfide (MoS2) connected to interdigitated metal electrodes were investigated. The MoS2 flake-based sensor detected a NO2 concentration as low as 1.2 ppm and exhibited excellent gas-sensing stability. Instead of metal electrodes, patterned graphene was used for charge collection in the MoS2-based sensing devices. An equation based on variable resistance terms was used to describe the sensing mechanism of the graphene/MoS2 device. Furthermore, the gas response characteristics of the heterostructured device on a flexible substrate were retained without serious performance degradation, even under mechanical deformation. This novel sensing structure based on a 2D heterostructure promises to provide a simple route to an essential sensing platform for wearable electronics.

  13. A Neural-FEM tool for the 2-D magnetic hysteresis modeling

    Energy Technology Data Exchange (ETDEWEB)

    Cardelli, E. [University of Perugia, Department of Engineering, Via G. Duranti 93, 06125 Perugia (Italy); Faba, A., E-mail: antonio.faba@unipg.it [University of Perugia, Department of Engineering, Via G. Duranti 93, 06125 Perugia (Italy); Laudani, A.; Lozito, G.M.; Riganti Fulginei, F.; Salvini, A. [Department of Engineering, Roma Tre University, Via V. Volterra 62, 00146 Rome (Italy)

    2016-04-01

    The aim of this work is to present a new tool for the analysis of magnetic field problems considering 2-D magnetic hysteresis. In particular, this tool makes use of the Finite Element Method to solve the magnetic field problem in real device, and fruitfully exploits a neural network (NN) for the modeling of 2-D magnetic hysteresis of materials. The NS has as input the magnetic inductions components B at the k-th simulation step and returns as output the corresponding values of the magnetic field H corresponding to the input pattern. It is trained by vector measurements performed on the magnetic material to be modeled. This input/output scheme is directly implemented in a FEM code employing the magnetic potential vector A formulation. Validations through measurements on a real device have been performed.

  14. Tracking objects outside the line of sight using 2D intensity images

    Science.gov (United States)

    Klein, Jonathan; Peters, Christoph; Martín, Jaime; Laurenzis, Martin; Hullin, Matthias B.

    2016-08-01

    The observation of objects located in inaccessible regions is a recurring challenge in a wide variety of important applications. Recent work has shown that using rare and expensive optical setups, indirect diffuse light reflections can be used to reconstruct objects and two-dimensional (2D) patterns around a corner. Here we show that occluded objects can be tracked in real time using much simpler means, namely a standard 2D camera and a laser pointer. Our method fundamentally differs from previous solutions by approaching the problem in an analysis-by-synthesis sense. By repeatedly simulating light transport through the scene, we determine the set of object parameters that most closely fits the measured intensity distribution. We experimentally demonstrate that this approach is capable of following the translation of unknown objects, and translation and orientation of a known object, in real time.

  15. Elastomeric 2D Grating and Hemispherical Optofluidic Chamber for Multifunctional Fluidic Sensing

    CERN Document Server

    Xu, Zhida

    2014-01-01

    We present an optofluidic sensor based on an elastomeric two-dimensional (2D) grating integrated inside a hemispherical fluid chamber. Laser beam is diffracted before (reflection) and after (transmission) going through the grating and liquid in the dome chamber. The sensing mechanism is investigated and simulated with a finite difference time domain (FDTD) based electromagnetic (EM) method. For experiment, by analyzing the size, power and shape of the 2D diffraction patterns, we can retrieve multiple parameters of the liquid including the refractive index, pressure and opacity with high sensitivity. We demonstrate that glucose concentration can be monitored when mixed in different concentrated phosphate buffered saline (PBS) solution. The free-solution binding of bovine serum albumin (BSA) and anti-BSA IgG is detected with this optical sensor. This low-cost, multifunctional and reliable optofluidic sensor has the potential to be used as monitor of biofluid such as blood in hemodialysis.

  16. Characteristic Evolution and Matching

    Directory of Open Access Journals (Sweden)

    Winicour Jeffrey

    2005-12-01

    Full Text Available I review the development of numerical evolution codes for general relativity based upon the characteristic initial value problem. Progress is traced from the early stage of 1D feasibility studies to 2D axisymmetric codes that accurately simulate the oscillations and gravitational collapse of relativistic stars and to current 3D codes that provide pieces of a binary black hole spacetime. A prime application of characteristic evolution is to compute waveforms via Cauchy-characteristic matching, which is also reviewed.

  17. Creating bio-inspired hierarchical 3D-2D photonic stacks via planar lithography on self-assembled inverse opals.

    Science.gov (United States)

    Burgess, Ian B; Aizenberg, Joanna; Lončar, Marko

    2013-12-01

    Structural hierarchy and complex 3D architecture are characteristics of biological photonic designs that are challenging to reproduce in synthetic materials. Top-down lithography allows for designer patterning of arbitrary shapes, but is largely restricted to planar 2D structures. Self-assembly techniques facilitate easy fabrication of 3D photonic crystals, but controllable defect-integration is difficult. In this paper we combine the advantages of top-down and bottom-up fabrication, developing two techniques to deposit 2D-lithographically-patterned planar layers on top of or in between inverse-opal 3D photonic crystals and creating hierarchical structures that resemble the architecture of the bright green wing scales of the butterfly, Parides sesostris. These fabrication procedures, combining advantages of both top-down and bottom-up fabrication, may prove useful in the development of omnidirectional coloration elements and 3D-2D photonic crystal devices.

  18. Creating bio-inspired hierarchical 3D-2D photonic stacks via planar lithography on self-assembled inverse opals

    CERN Document Server

    Burgess, Ian B; Loncar, Marko

    2012-01-01

    Structural hierarchy and complex 3D architecture are characteristics of biological photonic designs that are challenging to reproduce in synthetic materials. Top-down lithography allows for designer patterning of arbitrary shapes, but is largely restricted to planar 2D structures. Self-assembly techniques facilitate easy fabrication of 3D photonic crystals, but controllable defect-integration is difficult. In this paper we combine the advantages of top-down and bottom-up fabrication, developing two techniques to deposit 2D-lithographically-patterned planar layers on top of or in between inverse-opal 3D photonic crystals and creating hierarchical structures that resemble the architecture of the bright green wing scales of the butterfly, Parides sesostris. These fabrication procedures, combining advantages of both top-down and bottom-up fabrication, may prove useful in the development of omnidirectional coloration elements and 3D-2D photonic crystal devices.

  19. CH2D+, the Search for the Holy Grail

    CERN Document Server

    Roueff, E; Lis, D C; Wootten, A; Marcelino, N; cernicharo, J; Tercero, B

    2013-01-01

    CH2D+, the singly deuterated counterpart of CH3+, offers an alternative way to mediate formation of deuterated species at temperatures of several tens of K, as compared to the release of deuterated species from grains. We report a longstanding observational search for this molecular ion, whose rotational spectroscopy is not yet completely secure. We summarize the main spectroscopic properties of this molecule and discuss the chemical network leading to the formation of CH2D+, with explicit account of the ortho/para forms of H2, H3+ and CH3+. Astrochemical models support the presence of this molecular ion in moderately warm environments at a marginal level.

  20. EEG simulation by 2D interconnected chaotic oscillators

    Energy Technology Data Exchange (ETDEWEB)

    Kubany, Adam, E-mail: adamku@bgu.ac.i [Department of Industrial Engineering and Management, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 84105 (Israel); Mhabary, Ziv; Gontar, Vladimir [Department of Industrial Engineering and Management, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 84105 (Israel)

    2011-01-15

    Research highlights: ANN of 2D interconnected chaotic oscillators is explored for EEG simulation. An inverse problem solution (PRCGA) is proposed. Good matching between the simulated and experimental EEG signals has been achieved. - Abstract: An artificial neuronal network composed by 2D interconnected chaotic oscillators is explored for brain waves (EEG) simulation. For the inverse problem solution a parallel real-coded genetic algorithm (PRCGA) is proposed. In order to conduct thorough comparison between the simulated and target signal characteristics, a spectrum analysis of the signals is undertaken. A good matching between the theoretical and experimental EEG signals has been achieved. Numerical results of calculations are presented and discussed.

  1. 2D fluid simulations of interchange turbulence with ion dynamics

    DEFF Research Database (Denmark)

    Nielsen, Anders Henry; Madsen, Jens; Xu, G. S.

    2013-01-01

    In this paper we present a first principle global two-dimensional fluid model. The HESEL (Hot Edge SOL Electrostatic) model is a 2D numerical fluid code, based on interchange dynamics and includes besides electron also the ion pressure dynamic. In the limit of cold ions the model almost reduces......B vorticity as well as the ion diamagnetic vorticity. The 2D domain includes both open and closed field lines and is located on the out-board midplane of a tokamak. On open field field lines the parallel dynamics are parametrized as sink terms depending on the dynamic quantities; density, electron and ion...

  2. Recording 2-D Nutation NQR Spectra by Random Sampling Method.

    Science.gov (United States)

    Glotova, Olga; Sinyavsky, Nikolaj; Jadzyn, Maciej; Ostafin, Michal; Nogaj, Boleslaw

    2010-10-01

    The method of random sampling was introduced for the first time in the nutation nuclear quadrupole resonance (NQR) spectroscopy where the nutation spectra show characteristic singularities in the form of shoulders. The analytic formulae for complex two-dimensional (2-D) nutation NQR spectra (I = 3/2) were obtained and the condition for resolving the spectral singularities for small values of an asymmetry parameter η was determined. Our results show that the method of random sampling of a nutation interferogram allows significant reduction of time required to perform a 2-D nutation experiment and does not worsen the spectral resolution.

  3. Exact computation of scalar 2D aerial imagery

    Science.gov (United States)

    Gordon, Ronald L.

    2002-07-01

    An exact formulation of the problem of imaging a 2D object through a Koehler illumination system is presented; the accurate simulation of a real layout is then not time- limited but memory-limited. The main idea behind the algorithm is that the boundary of the region that comprise a typical TCC Is made up of circular arcs, and therefore the area - which determines the value of the TCC - should be exactly computable in terms of elementary analytical functions. A change to integration around the boundary leads to an expression with minimal dependence on expensive functions such as arctangents and square roots. Numerical comparisons are made for a simple 2D structure.

  4. GENERALIZED VARIATIONAL OPTIMAZATION ANALYSIS FOR 2-D FLOW FIELD

    Institute of Scientific and Technical Information of China (English)

    HUANG Si-xun; XU Ding-hua; LAN Wei-ren; TENG Jia-jun

    2005-01-01

    The Variational Optimization Analysis Method (VOAM) for 2-D flow field suggested by Sasaki was reviewed first. It is known that the VOAM can be used efficiently in most cases. However, in the cases where there are high frequency noises in 2-D flow field, it appears to be inefficient. In the present paper, based on Sasaki's VOAM, a Generalized Variational Optimization Analysis Method (GVOAM) was proposed with regularization ideas, which could deal well with flow fields containing high frequency noises. A numerical test shows that observational data can be both variationally optimized and filtered, and therefore the GVOAM is an efficient method.

  5. Isotropic 2D quadrangle meshing with size and orientation control

    KAUST Repository

    Pellenard, Bertrand

    2011-12-01

    We propose an approach for automatically generating isotropic 2D quadrangle meshes from arbitrary domains with a fine control over sizing and orientation of the elements. At the heart of our algorithm is an optimization procedure that, from a coarse initial tiling of the 2D domain, enforces each of the desirable mesh quality criteria (size, shape, orientation, degree, regularity) one at a time, in an order designed not to undo previous enhancements. Our experiments demonstrate how well our resulting quadrangle meshes conform to a wide range of input sizing and orientation fields.

  6. On the Nonrelativistic 2D Purely Magnetic Supersymmetric Pauli Operator

    OpenAIRE

    Grinevich, P.; Mironov, A.(Lebedev Physics Institute; ITEP, Moscow, Russia); Novikov, S.

    2011-01-01

    The Complete Manifold of Ground State Eigenfunctions for the Purely Magnetic 2D Pauli Operator is considered as a by-product of the new reduction found by the present authors few years ago for the Algebrogeometric Inverse Spectral Data (i.e. Riemann Surfaces and Divisors). This reduction is associated with the (2+1) Soliton Hierarhy containing a 2D analog of the famous "Burgers System". This article contains also exposition of the previous works made since 1980 including the first topological...

  7. Discrete tomographic reconstruction of 2D polycrystal orientation maps from X-ray diffraction projections using Gibbs priors

    DEFF Research Database (Denmark)

    Rodek, L.; Knudsen, E.; Poulsen, H.F.;

    2005-01-01

    The determination of crystalline structures is a demanding and fundamental task of crystallography. This paper offers a new approach for rendering a 2D grain map of a polycrystal based on an orientation map reconstructed from X-ray diffraction patterns. The orientation map is produced by a Bayesian...

  8. Distinctive Features and Evolution of the Prehistoric Settlement Pattern in the Liyang Plain%澧阳平原史前聚落形态的特点与演变

    Institute of Scientific and Technical Information of China (English)

    裴安平

    2004-01-01

    A large number of Neolithic settlements have been discovered in the Liyang Plain of northwestern Hunan. Based upon investigation on the distribution and size of settlements and study into their entire pattern, house forms, burial ranks and organization modes, the evolution of the prehistoric settlement pattern in this region can be divided into three stages represented by ditch-surrounded settlements, walled ones and settlement groups. This developmental course reflects the influence of natural environments, agricultural production, the origination and growth of private ownership and the development and organization structure of human society upon the evolution of the settlement pattern. It also demonstrates the stages and distinctive features of the advance of prehistoric local settlements towards civilized society.

  9. Adaptive reorganization of 2D molecular nanoporous network induced by coadsorbed guest molecule.

    Science.gov (United States)

    Zheng, Qing-Na; Wang, Lei; Zhong, Yu-Wu; Liu, Xuan-He; Chen, Ting; Yan, Hui-Juan; Wang, Dong; Yao, Jian-Nian; Wan, Li-Jun

    2014-03-25

    The ordered array of nanovoids in nanoporous networks, such as honeycomb, Kagome, and square, provides a molecular template for the accommodation of "guest molecules". Compared with the commonly studied guest molecules featuring high symmetry evenly incorporated into the template, guest molecules featuring lower symmetry are rare to report. Herein, we report the formation of a distinct patterned superlattice of guest molecules by selective trapping of guest molecules into the honeycomb network of trimesic acid (TMA). Two distinct surface patterns have been achieved by the guest inclusion induced adaptive reconstruction of a 2D molecular nanoporous network. The honeycomb networks can synergetically tune the arrangement upon inclusion of the guest molecules with different core size but similar peripherals groups, resulting in a trihexagonal Kagome or triangular patterns.

  10. Patterning mechanisms in the evolution of derived developmental life histories: the role of Wnt signaling in axis formation of the direct-developing sea urchin Heliocidaris erythrogramma.

    Science.gov (United States)

    Kauffman, Jeffrey S; Raff, Rudolf A

    2003-12-01

    A number of echinoderm species have replaced indirect development with highly modified direct-developmental modes, and provide models for the study of the evolution of early embryonic development. These divergent early ontogenies may differ significantly in life history, oogenesis, cleavage pattern, cell lineage, and timing of cell fate specification compared with those of indirect-developing species. No direct-developing echinoderm species has been studied at the level of molecular specification of embryonic axes. Here we report the first functional analysis of Wnt pathway components in Heliocidaris erythrogramma, a direct-developing sea urchin. We show by misexpression and dominant negative knockout construct expression that Wnt8 and TCF are functionally conserved in the generation of the primary (animal/vegetal) axis in two independently evolved direct-developing sea urchins. Thus, Wnt pathway signaling is an overall deeply conserved mechanism for axis formation that transcends radical changes to early developmental ontogenies. However, the timing of expression and linkages between Wnt8, TCF, and components of the PMC-specification pathway have changed. These changes correlate with the transition from an indirect- to a direct-developing larval life history.

  11. Some remarks on the role of the boundary layers in decaying 2D turbulence in containers no-slip walls

    Energy Technology Data Exchange (ETDEWEB)

    Clercx, H.J.H.; Van Heijst, G.J.F. [Eindhoven University of Technology, Eindhoven (Netherlands). J.M. Burges Centre for Fluid Dynamics, Dept. of Physics

    1999-12-01

    Direct numerical simulations of decaying two-dimensional (2D) turbulence inside a square container with no-slip boundaries have been carried out for Reynolds numbers up to 2000. The role of the boundary layers during the decay process has been illustrated with ensemble-averaged results for the power law behaviour of several characteristic properties of the coherent vortices which emerge during the decay of 2D turbulence. The evolution of the vortex density, the average vortex radius, the enstrophy and the vorticity extrema have been computed. An algebraic decay regime has been observed during the initial turbulent decay stage. The computed decay exponents disagree, however, with the exponents from the classical scaling theory for 2D decaying turbulence on an unbounded domain.

  12. Fast 2D-DCT implementations for VLIW processors

    OpenAIRE

    Sohm, OP; Canagarajah, CN; Bull, DR

    1999-01-01

    This paper analyzes various fast 2D-DCT algorithms regarding their suitability for VLIW processors. Operations for truncation or rounding which are usually neglected in proposals for fast algorithms have also been taken into consideration. Loeffler's algorithm with parallel multiplications was found to be most suitable due to its parallel structure

  13. 2D nanomaterials based electrochemical biosensors for cancer diagnosis.

    Science.gov (United States)

    Wang, Lu; Xiong, Qirong; Xiao, Fei; Duan, Hongwei

    2017-03-15

    Cancer is a leading cause of death in the world. Increasing evidence has demonstrated that early diagnosis holds the key towards effective treatment outcome. Cancer biomarkers are extensively used in oncology for cancer diagnosis and prognosis. Electrochemical sensors play key roles in current laboratory and clinical analysis of diverse chemical and biological targets. Recent development of functional nanomaterials offers new possibilities of improving the performance of electrochemical sensors. In particular, 2D nanomaterials have stimulated intense research due to their unique array of structural and chemical properties. The 2D materials of interest cover broadly across graphene, graphene derivatives (i.e., graphene oxide and reduced graphene oxide), and graphene-like nanomaterials (i.e., 2D layered transition metal dichalcogenides, graphite carbon nitride and boron nitride nanomaterials). In this review, we summarize recent advances in the synthesis of 2D nanomaterials and their applications in electrochemical biosensing of cancer biomarkers (nucleic acids, proteins and some small molecules), and present a personal perspective on the future direction of this area.

  14. The partition function of 2d string theory

    CERN Document Server

    Dijkgraaf, R; Plesser, R

    1993-01-01

    We derive a compact and explicit expression for the generating functional of all correlation functions of tachyon operators in 2D string theory. This expression makes manifest relations of the $c=1$ system to KP flow and $W_{1+\\infty}$ constraints. Moreover we derive a Kontsevich-Penner integral representation of this generating functional.

  15. The toroidal Hausdorff dimension of 2d Euclidean quantum gravity

    DEFF Research Database (Denmark)

    Ambjorn, Jan; Budd, Timothy George

    2013-01-01

    The lengths of shortest non-contractible loops are studied numerically in 2d Euclidean quantum gravity on a torus coupled to conformal field theories with central charge less than one. We find that the distribution of these geodesic lengths displays a scaling in agreement with a Hausdorff dimension...

  16. Validation of minor species of the MIPAS2D database

    Directory of Open Access Journals (Sweden)

    Enzo Papandrea

    2014-01-01

    Full Text Available The MIPAS2D [Dinelli et al., 2010] database has been developed applying the tomographic analysis technique GMTR [Carlotti et al., 2001] to measurements acquired in the nominal observation mode of the complete MIPAS (Michelson Interferometer for Passive Atmosphere Sounding [Fischer et al., 2008] mission. […

  17. The 2D Boussinesq equations with logarithmically supercritical velocities

    CERN Document Server

    Chae, Dongho

    2011-01-01

    This paper investigates the global (in time) regularity of solutions to a system of equations that generalize the vorticity formulation of the 2D Boussinesq-Navier-Stokes equations. The velocity $u$ in this system is related to the vorticity $\\omega$ through the relations $u=\

  18. 2D InP photonic crystal fabrication process development

    NARCIS (Netherlands)

    Rong, B.; Van der Drift, E.; Van der Heijden, R.W.; Salemink, H.W.M.

    2006-01-01

    We have developed a reliable process to fabricate high quality 2D air-hole and dielectric column InP photonic crystals with a high aspect ratio on a STS production tool using ICP N2+Cl2 plasma. The photonic crystals have a triangular lattice with lattice constant of 400 nm and air-hole and dielectri

  19. The Analytical Approximate Solution of the 2D Thermal Displacement

    Institute of Scientific and Technical Information of China (English)

    Chu-QuanGuan; Zeng-YuanGuo; 等

    1996-01-01

    The 2D plane gas flow under heating (with nonentity boundary condition)has been discussed by the analytical approach in this paper.The approximate analytical solutions have been obtained for the flow passing various kinds of heat sources.Solutions demonstrate the thermal displacement phenomena are strongly depend on the heating intensity.

  20. Band Alignment of 2D Transition Metal Dichalcogenide Heterojunctions

    KAUST Repository

    Chiu, Ming Hui

    2016-09-20

    It is critically important to characterize the band alignment in semiconductor heterojunctions (HJs) because it controls the electronic and optical properties. However, the well-known Anderson\\'s model usually fails to predict the band alignment in bulk HJ systems due to the presence of charge transfer at the interfacial bonding. Atomically thin 2D transition metal dichalcogenide materials have attracted much attention recently since the ultrathin HJs and devices can be easily built and they are promising for future electronics. The vertical HJs based on 2D materials can be constructed via van der Waals stacking regardless of the lattice mismatch between two materials. Despite the defect-free characteristics of the junction interface, experimental evidence is still lacking on whether the simple Anderson rule can predict the band alignment of HJs. Here, the validity of Anderson\\'s model is verified for the 2D heterojunction systems and the success of Anderson\\'s model is attributed to the absence of dangling bonds (i.e., interface dipoles) at the van der Waal interface. The results from the work set a foundation allowing the use of powerful Anderson\\'s rule to determine the band alignments of 2D HJs, which is beneficial to future electronic, photonic, and optoelectronic devices. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Rheological Properties of Quasi-2D Fluids in Microgravity

    Science.gov (United States)

    Stannarius, Ralf; Trittel, Torsten; Eremin, Alexey; Harth, Kirsten; Clark, Noel; Maclennan, Joseph; Glaser, Matthew; Park, Cheol; Hall, Nancy; Tin, Padetha

    2015-01-01

    In recent years, research on complex fluids and fluids in restricted geometries has attracted much attention in the scientific community. This can be attributed not only to the development of novel materials based on complex fluids but also to a variety of important physical phenomena which have barely been explored. One example is the behavior of membranes and thin fluid films, which can be described by two-dimensional (2D) rheology behavior that is quite different from 3D fluids. In this study, we have investigated the rheological properties of freely suspended films of a thermotropic liquid crystal in microgravity experiments. This model system mimics isotropic and anisotropic quasi 2D fluids [46]. We use inkjet printing technology to dispense small droplets (inclusions) onto the film surface. The motion of these inclusions provides information on the rheological properties of the films and allows the study of a variety of flow instabilities. Flat films have been investigated on a sub-orbital rocket flight and curved films (bubbles) have been studied in the ISS project OASIS. Microgravity is essential when the films are curved in order to avoid sedimentation. The experiments yield the mobility of the droplets in the films as well as the mutual mobility of pairs of particles. Experimental results will be presented for 2D-isotropic (smectic-A) and 2D-nematic (smectic-C) phases.

  2. Research Synthesis and Characterization of 2D Conjugated Polymers

    Science.gov (United States)

    2007-07-13

    polythiophene chain on the Scheme should necessarily result in a continuous brick wall 2D structure). Furthermore, the design should eliminate any...Photoelectron Spectroscopy and Ultraviolet Photoelectron Spectroscopy are under way. We have also conducted preliminary experiments on the two other low

  3. Design of the LRP airfoil series using 2D CFD

    DEFF Research Database (Denmark)

    Zahle, Frederik; Bak, Christian; Sørensen, Niels N.;

    2014-01-01

    This paper describes the design and wind tunnel testing of a high-Reynolds number, high lift airfoil series designed for wind turbines. The airfoils were designed using direct gradient- based numerical multi-point optimization based on a Bezier parameterization of the shape, coupled to the 2D Nav...

  4. BPS black holes in N=2 D=4 gauged supergravities

    NARCIS (Netherlands)

    Hristov, K.; Looyestijn, H.T.; Vandoren, S.J.G.

    2010-01-01

    We construct and analyze BPS black hole solutions in gauged N=2, D=4 supergravity with charged hypermultiplets. A class of solutions can be found through spontaneous symmetry breaking in vacua that preserve maximal supersymmetry. The resulting black holes do not carry any hair for the scalars. We de

  5. Maximizing entropy of image models for 2-D constrained coding

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Danieli, Matteo; Burini, Nino;

    2010-01-01

    £ 2 squares contains all 0s or all 1s. The maximum values of the entropy for the constraints are estimated and binary PRF satisfying the constraint are characterized and optimized w.r.t. the entropy. The maximum binary PRF entropy is 0.839 bits/symbol for the no uniform squares constraint. The entropy...... of the Markov random field defined by the 2-D constraint is estimated to be (upper bounded by) 0.8570 bits/symbol using the iterative technique of Belief Propagation on 2 £ 2 finite lattices. Based on combinatorial bounding techniques the maximum entropy for the constraint was determined to be 0.848.......This paper considers estimating and maximizing the entropy of two-dimensional (2-D) fields with application to 2-D constrained coding. We consider Markov random fields (MRF), which have a non-causal description, and the special case of Pickard random fields (PRF). The PRF are 2-D causal finite...

  6. The Anglo-Australian Observatory's 2dF Facility

    CERN Document Server

    Lewis, I J; Taylor, K; Glazebrook, K; Bailey, J A; Baldry, I K; Barton, J R; Bridges, T J; Dalton, G B; Farrell, T J; Gray, P M; Lankshear, A; McCowage, C; Parry, I R; Sharples, R M; Shortridge, K; Smith, G A; Stevenson, J; Straede, J O; Waller, L G; Whittard, J D; Wilcox, J K; Willis, K C

    2002-01-01

    The 2dF (Two-degree Field) facility at the prime focus of the Anglo-Australian Telescope provides multiple object spectroscopy over a 2 degree field of view. Up to 400 target fibres can be independently positioned by a complex robot. Two spectrographs provide spectra with resolutions of between 500 and 2000, over wavelength ranges of 440nm and 110nm respectively. The 2dF facility began routine observations in 1997. 2dF was designed primarily for galaxy redshift surveys and has a number of innovative features. The large corrector lens incorporates an atmospheric dispersion compensator, essential for wide wavelength coverage with small diameter fibres. The instrument has two full sets of fibres on separate field plates, so that re-configuring can be done in parallel with observing. The robot positioner places one fibre every 6 seconds, to a precision of 0.3 arcsec (20micron) over the full field. All components of 2dF, including the spectrographs, are mounted on a 5-m diameter telescope top-end ring for ease of ...

  7. Nonlinear excursions of particles in ideal 2D flows

    DEFF Research Database (Denmark)

    Aref, Hassan; Pedersen, Johan Rønby; Stremler, Mark A.;

    2010-01-01

    A number of problems related to particle trajectories in ideal 2D flows are discussed. Both regular particle paths, corresponding to integrable dynamics, and irregular or chaotic paths may arise. Examples of both types are shown. Sometimes, in the same flow, certain particles will follow regular ...

  8. Approximate 2D inversion of airborne TEM data

    DEFF Research Database (Denmark)

    Christensen, N.B.; Wolfgram, Peter

    2006-01-01

    We propose an approximate two-dimensional inversion procedure for transient electromagnetic data. The method is a two-stage procedure, where data are first inverted with 1D multi-layer models. The 1D model section is then considered as data for the next inversion stage that produces the 2D model ....... Application to GEOTEM data over the Harmony nickel sulphide deposit recovered the three dipping conductors in the 2D section despite their complex structure and high conductivity contrast.......We propose an approximate two-dimensional inversion procedure for transient electromagnetic data. The method is a two-stage procedure, where data are first inverted with 1D multi-layer models. The 1D model section is then considered as data for the next inversion stage that produces the 2D model...... section. For moving platform data there is translational invariance and the second part of the inversion becomes a deconvolution. The convolution kernels are computed by perturbing one model element in an otherwise homogeneous 2D section and calculating full nonlinear responses. These responses...

  9. CFD code comparison for 2D airfoil flows

    DEFF Research Database (Denmark)

    Sørensen, Niels N.; Méndez, B.; Muñoz, A.;

    2016-01-01

    The current paper presents the effort, in the EU AVATAR project, to establish the necessary requirements to obtain consistent lift over drag ratios among seven CFD codes. The flow around a 2D airfoil case is studied, for both transitional and fully turbulent conditions at Reynolds numbers of 3 × ...

  10. Discrepant Results in a 2-D Marble Collision

    Science.gov (United States)

    Kalajian, Peter

    2013-01-01

    Video analysis of 2-D collisions is an excellent way to investigate conservation of linear momentum. The often-desired experimental design goal is to minimize the momentum loss in order to demonstrate the conservation law. An air table with colliding pucks is an ideal medium for this experiment, but such equipment is beyond the budget of many…

  11. CANONICAL COMPUTATIONAL FORMS FOR AR 2-D SYSTEMS

    NARCIS (Netherlands)

    ROCHA, P; WILLEMS, JC

    1990-01-01

    A canonical form for AR 2-D systems representations is introduced. This yields a method for computing the system trajectories by means of a line-by-line recursion, and displays some relevant information about the system structure such as the choice of inputs and initial conditions.

  12. A VARIATIONAL MODEL FOR 2-D MICROPOLAR BLOOD FLOW

    Institute of Scientific and Technical Information of China (English)

    He Ji-huan

    2003-01-01

    The micropolar fluid model is an essential generalization of the well-established Navier-Stokes model in the sense that it takes into account the microstructure of the fluid.This paper is devolted to establishing a variational principle for 2-D incompressible micropolar blood flow.

  13. Computational study of interfaces and edges of 2D materials

    NARCIS (Netherlands)

    Farmanbar Gelepordsari, M.

    2016-01-01

    The discovery of graphene and its intriguing properties has given birth to the field of two-dimensional (2D) materials. These materials are characterized by a strong covalent bonding between the atoms within a plane, but weak, van derWaals, bonding between the planes. Such materials can be isolated

  14. Horns Rev II, 2D-Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Brorsen, Michael

    This report is an extension of the study presented in Lykke Andersen and Brorsen, 2006 and includes results from the irregular wave tests, where Lykke Andersen & Brorsen, 2006 focused on regular waves. The 2D physical model tests were carried out in the shallow wave flume at Dept. of Civil...

  15. Geodesic patterns

    KAUST Repository

    Pottmann, Helmut

    2010-07-26

    Geodesic curves in surfaces are not only minimizers of distance, but they are also the curves of zero geodesic (sideways) curvature. It turns out that this property makes patterns of geodesics the basic geometric entity when dealing with the cladding of a freeform surface with wooden panels which do not bend sideways. Likewise a geodesic is the favored shape of timber support elements in freeform architecture, for reasons of manufacturing and statics. Both problem areas are fundamental in freeform architecture, but so far only experimental solutions have been available. This paper provides a systematic treatment and shows how to design geodesic patterns in different ways: The evolution of geodesic curves is good for local studies and simple patterns; the level set formulation can deal with the global layout of multiple patterns of geodesics; finally geodesic vector fields allow us to interactively model geodesic patterns and perform surface segmentation into panelizable parts. © 2010 ACM.

  16. Cytochrome P-450 2D6 (CYP2D6) Genotype and Breast Cancer Recurrence in Tamoxifen-Treated Patients

    DEFF Research Database (Denmark)

    Ahern, Thomas P; Hertz, Daniel L; Damkier, Per;

    2017-01-01

    -infiltrated tissues, all of which showed excellent CYP2D6 genotype agreement. We applied these concordance data to a quantitative bias analysis of the subset of the 31 studies that were based on genotypes from tumor-infiltrated tissue to examine whether genotyping errors substantially biased estimates of association....... The bias analysis showed negligible bias by discordant genotypes. Summary estimates of association, with or without bias adjustment, indicated no clinically important association between CYP2D6 genotype and breast cancer survival in tamoxifen-treated women....

  17. WE-AB-BRA-07: Quantitative Evaluation of 2D-2D and 2D-3D Image Guided Radiation Therapy for Clinical Trial Credentialing, NRG Oncology/RTOG

    Energy Technology Data Exchange (ETDEWEB)

    Giaddui, T; Yu, J; Xiao, Y [Thomas Jefferson University, Philadelphia, PA (United States); Jacobs, P [MIM Software, Inc, Cleavland, Ohio (United States); Manfredi, D; Linnemann, N [IROC Philadelphia, RTQA Center, Philadelphia, PA (United States)

    2015-06-15

    Purpose: 2D-2D kV image guided radiation therapy (IGRT) credentialing evaluation for clinical trial qualification was historically qualitative through submitting screen captures of the fusion process. However, as quantitative DICOM 2D-2D and 2D-3D image registration tools are implemented in clinical practice for better precision, especially in centers that treat patients with protons, better IGRT credentialing techniques are needed. The aim of this work is to establish methodologies for quantitatively reviewing IGRT submissions based on DICOM 2D-2D and 2D-3D image registration and to test the methodologies in reviewing 2D-2D and 2D-3D IGRT submissions for RTOG/NRG Oncology clinical trials qualifications. Methods: DICOM 2D-2D and 2D-3D automated and manual image registration have been tested using the Harmony tool in MIM software. 2D kV orthogonal portal images are fused with the reference digital reconstructed radiographs (DRR) in the 2D-2D registration while the 2D portal images are fused with DICOM planning CT image in the 2D-3D registration. The Harmony tool allows alignment of the two images used in the registration process and also calculates the required shifts. Shifts calculated using MIM are compared with those submitted by institutions for IGRT credentialing. Reported shifts are considered to be acceptable if differences are less than 3mm. Results: Several tests have been performed on the 2D-2D and 2D-3D registration. The results indicated good agreement between submitted and calculated shifts. A workflow for reviewing these IGRT submissions has been developed and will eventually be used to review IGRT submissions. Conclusion: The IROC Philadelphia RTQA center has developed and tested a new workflow for reviewing DICOM 2D-2D and 2D-3D IGRT credentialing submissions made by different cancer clinical centers, especially proton centers. NRG Center for Innovation in Radiation Oncology (CIRO) and IROC RTQA center continue their collaborative efforts to enhance

  18. Regional Distribution and Its Pattern Evolution of the Winter Olympics Gold Medals%冬奥会金牌区域归属与格局演变

    Institute of Scientific and Technical Information of China (English)

    刘志华

    2014-01-01

    Through the quantitative statistics and regional distribution of the 22 games' gold medals of Winter Olympics from 1924 to 2014,the paper analyzes the dynamic change and pattern evolution of various regional gold medals. It draws a conclusion that the competitive pattern shows the strong is always strong,the polarization is serious with the legible boundary between strong area and weak area,a weak one is difficult to upgrade into strong area for a long time. European and American powers represented by Russia,Germany,Norway and USA have long-term regional monopoly with balanced development. The common countries obviously show selective advantage with unbalanced development, and the weak countries have well development trend by giving priority to choose the breakthrough according to respective national conditions.The fierce competition in the strong area and the rise of some weak ones result in a dispersed trend of gold medals distribution,the difference of competitive strength in various areas is diminishing in the shift. It should be to achieve the harmonious development of winter and summer Olympics in China by project planning based on the regional characteristics according to the evolution rule of competitive pattern.%通过对1924~2014年举办过的22届冬季奥运会金牌数及区域归属进行分类统计,分析各区域金牌的动态变化及竞技格局的演变。得出结论:竞技格局呈现出强者恒强的态势,强势区域与弱势区域界限清晰,两级分化严重,长时间内会继续维持,弱势区域很难升级到强势区域。以俄罗斯、德国、挪威、美国为代表的欧美强势国形成长期性区域垄断,项目发展相对均衡;较强国家项目发展不均衡,存在明显的选择性优势;弱势国家根据各自的国情,有重点地选择性突破,形成了良好的发展态势。强势区域的激烈竞争,弱势区域的突破崛起,导致金牌分布趋于分散,各区域的竞

  19. 2d-LCA - an alternative to x-wires

    Science.gov (United States)

    Puczylowski, Jaroslaw; Hölling, Michael; Peinke, Joachim

    2014-11-01

    The 2d-Laser Cantilever Anemometer (2d-LCA) is an innovative sensor for two-dimensional velocity measurements in fluids. It uses a micostructured cantilever made of silicon and SU-8 as a sensing element and is capable of performing mesurements with extremly high temporal resolutions up to 150 kHz. The size of the cantilever defines its spatial resolution, which is in the order of 150 μm only. Another big feature is a large angular range of 180° in total. The 2d-LCA has been developed as an alternative measurement method to x-wires with the motivation to create a sensor that can operate in areas where the use of hot-wire anemometry is difficult. These areas include measurements in liquids and in near-wall or particle-laden flows. Unlike hot-wires, the resolution power of the 2d-LCA does not decrease with increasing flow velocity, making it particularly suitable for measurements in high speed flows. Comparative measurements with the 2d-LCA and hot-wires have been carried out in order to assess the performance of the new anemometer. The data of both measurement techniques were analyzed using the same stochastic methods including a spectral analysis as well as an inspection of increment statistics and structure functions. Furthermore, key parameters, such as mean values of both velocity components, angles of attack and the characteristic length scales were determined from both data sets. The analysis reveals a great agreement between both anemometers and thus confirms the new approach.

  20. Half-metallicity in 2D organometallic honeycomb frameworks

    Science.gov (United States)

    Sun, Hao; Li, Bin; Zhao, Jin

    2016-10-01

    Half-metallic materials with a high Curie temperature (T C) have many potential applications in spintronics. Magnetic metal free two-dimensional (2D) half-metallic materials with a honeycomb structure contain graphene-like Dirac bands with π orbitals and show excellent aspects in transport properties. In this article, by investigating a series of 2D organometallic frameworks with a honeycomb structure using first principles calculations, we study the origin of forming half-metallicity in this kind of 2D organometallic framework. Our analysis shows that charge transfer and covalent bonding are two crucial factors in the formation of half-metallicity in organometallic frameworks. (i) Sufficient charge transfer from metal atoms to the molecules is essential to form the magnetic centers. (ii) These magnetic centers need to be connected through covalent bonding, which guarantee the strong ferromagnetic (FM) coupling. As examples, the organometallic frameworks composed by (1,3,5)-benzenetricarbonitrile (TCB) molecules with noble metals (Au, Ag, Cu) show half-metallic properties with T C as high as 325 K. In these organometallic frameworks, the strong electronegative cyano-groups (CN groups) drive the charge transfer from metal atoms to the TCB molecules, forming the local magnetic centers. These magnetic centers experience strong FM coupling through the d-p covalent bonding. We propose that most of the 2D organometallic frameworks composed by molecule—CN—noble metal honeycomb structures contain similar half metallicity. This is verified by replacing TCB molecules with other organic molecules. Although the TCB-noble metal organometallic framework has not yet been synthesized, we believe the development of synthesizing techniques and facility will enable the realization of them. Our study provides new insight into the 2D half-metallic material design for the potential applications in nanotechnology.